ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A01 compound treatment -0.0818 0.176 0.65 -0.0842 0.171 0.63 0.9094 0.9999 SpOx1.1_003873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A02 compound treatment -0.0589 0.199 0.74 -0.0662 0.189 0.7 1.0164 0.9997 SpOx1.1_003874 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A03 compound treatment -0.0509 0.207 0.77 -0.1053 0.15 0.56 0.9349 0.9876 SpOx1.1_003875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A04 compound treatment -0.0668 0.191 0.71 -0.1013 0.154 0.57 0.9038 0.9943 SpOx1.1_003876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A05 compound treatment -0.0599 0.198 0.73 -0.0802 0.175 0.65 0.9771 0.9982 SpOx1.1_003877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A06 compound treatment -0.0649 0.193 0.71 -0.0952 0.16 0.59 0.9247 0.9957 SpOx1.1_003878 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A07 compound treatment -0.0459 0.212 0.78 -0.0993 0.156 0.58 0.9637 0.9887 2144277 SpOx1.1_003879 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A08 compound treatment -0.0589 0.199 0.74 -0.0892 0.166 0.62 0.9561 0.996 SpOx1.1_003880 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A09 compound treatment -0.0758 0.182 0.67 -0.0722 0.183 0.68 0.9565 1.0 SpOx1.1_003881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A10 compound treatment -0.0859 0.172 0.64 -0.0872 0.168 0.62 0.8908 0.9999 SpOx1.1_003882 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A11 compound treatment -0.0829 0.175 0.65 -0.0752 0.18 0.67 0.93 0.9999 SpOx1.1_003883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A12 compound treatment -0.0789 0.179 0.66 -0.0792 0.176 0.65 0.93 1.0 SpOx1.1_003884 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A13 compound treatment -0.0839 0.174 0.64 -0.0882 0.167 0.62 0.8934 0.9998 SpOx1.1_003885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A14 compound treatment -0.0998 0.158 0.59 -0.0882 0.167 0.62 0.8518 0.9996 SpOx1.1_003886 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A15 compound treatment -0.0869 0.171 0.63 -0.0842 0.171 0.63 0.896 1.0 SpOx1.1_003887 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A16 compound treatment -0.0909 0.167 0.62 -0.0982 0.157 0.58 0.8489 0.9995 SpOx1.1_003888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A17 compound treatment -0.0949 0.163 0.6 -0.0942 0.161 0.6 0.8489 1.0 SpOx1.1_003889 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A18 compound treatment -0.0919 0.166 0.61 -0.0842 0.171 0.63 0.8829 0.9999 SpOx1.1_003890 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A19 compound treatment -0.0939 0.164 0.61 -0.0882 0.167 0.62 0.8672 1.0 SpOx1.1_003891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A20 compound treatment -0.0889 0.169 0.63 -0.0942 0.161 0.6 0.8646 0.9997 SpOx1.1_003892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A21 compound treatment -0.1068 0.151 0.56 -0.0852 0.17 0.63 0.8413 0.9982 SpOx1.1_003893 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A22 compound treatment -0.1078 0.15 0.56 -0.0922 0.163 0.6 0.8204 0.9991 SpOx1.1_003894 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A23 mock treatment -0.0839 0.174 0.64 -0.0822 0.173 0.64 0.9091 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 A24 mock treatment -0.5121 -0.254 -0.94 -0.5059 -0.251 -0.93 -1.3206 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B01 compound treatment -0.0189 0.239 0.88 -0.0092 0.246 0.91 1.2702 0.9999 SpOx1.1_003895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B02 compound treatment -0.0069 0.251 0.93 -0.0012 0.254 0.94 1.3227 1.0 2143117 SpOx1.1_003896 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCN(C)Cc9ccccc9)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B03 compound treatment 0.0041 0.262 0.97 -0.0012 0.254 0.94 1.3515 0.9999 SpOx1.1_003897 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B04 compound treatment 0.0141 0.272 1.01 -0.0062 0.249 0.92 1.3644 0.9991 SpOx1.1_003898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B05 compound treatment 0.0201 0.278 1.03 0.0108 0.266 0.99 1.4247 0.9998 SpOx1.1_003899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B06 compound treatment -0.0059 0.252 0.93 0.0028 0.258 0.96 1.3359 0.9999 SpOx1.1_003900 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B07 compound treatment 0.0071 0.265 0.98 -0.0022 0.253 0.94 1.3567 0.9998 SpOx1.1_003901 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B08 compound treatment 0.0151 0.273 1.01 0.0168 0.272 1.01 1.4274 1.0 SpOx1.1_003902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B09 compound treatment -0.0029 0.255 0.94 0.0138 0.269 1.0 1.3725 0.9996 SpOx1.1_003903 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B10 compound treatment 0.0061 0.264 0.98 0.0128 0.268 0.99 1.3933 1.0 SpOx1.1_003904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B11 compound treatment 0.0041 0.262 0.97 0.0078 0.263 0.97 1.375 1.0 SpOx1.1_003905 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B12 compound treatment -0.0029 0.255 0.94 0.0048 0.26 0.96 1.349 0.9999 SpOx1.1_003906 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B13 compound treatment 0.0091 0.267 0.99 0.0178 0.273 1.01 1.4143 0.9999 SpOx1.1_003907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B14 compound treatment 0.0121 0.27 1.0 -0.0032 0.252 0.93 1.367 0.9994 SpOx1.1_003908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B15 compound treatment 0.0091 0.267 0.99 8.0E-4 0.256 0.95 1.3697 0.9998 SpOx1.1_003909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B16 compound treatment 0.0061 0.264 0.98 -0.0012 0.254 0.94 1.3566 0.9998 SpOx1.1_003910 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B17 compound treatment 0.0191 0.277 1.03 0.0068 0.262 0.97 1.4116 0.9996 SpOx1.1_003911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B18 compound treatment 0.0141 0.272 1.01 0.0018 0.257 0.95 1.3855 0.9996 SpOx1.1_003912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B19 compound treatment 0.0111 0.269 1.0 0.0138 0.269 1.0 1.4091 1.0 SpOx1.1_003913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B20 compound treatment 0.0061 0.264 0.98 0.0138 0.269 1.0 1.396 0.9999 2143725 SpOx1.1_003914 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B21 compound treatment 0.0141 0.272 1.01 0.0208 0.276 1.02 1.4352 1.0 SpOx1.1_003915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B22 compound treatment -0.0049 0.253 0.94 -0.0062 0.249 0.92 1.3148 1.0 SpOx1.1_003916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B23 mock treatment 0.0171 0.275 1.02 -0.0042 0.251 0.93 1.3774 0.999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 B24 mock treatment -0.5101 -0.252 -0.93 -0.5049 -0.25 -0.92 -1.3127 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C01 compound treatment -0.0189 0.239 0.88 -0.0072 0.248 0.92 1.2756 0.9998 SpOx1.1_003917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C02 compound treatment 0.0031 0.261 0.97 -0.0092 0.246 0.91 1.3278 0.9996 SpOx1.1_003918 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C03 compound treatment -0.0049 0.253 0.94 -0.0082 0.247 0.92 1.3096 0.9999 SpOx1.1_003919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C04 compound treatment 0.0011 0.259 0.96 -0.0192 0.236 0.87 1.2964 0.999 SpOx1.1_003920 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C05 compound treatment 0.0061 0.264 0.98 -0.0212 0.234 0.87 1.3043 0.9982 SpOx1.1_003921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C06 compound treatment -0.0209 0.237 0.88 -0.0062 0.249 0.92 1.2729 0.9997 SpOx1.1_003922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C07 compound treatment -0.0149 0.243 0.9 -0.0062 0.249 0.92 1.2886 0.9999 SpOx1.1_003923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C08 compound treatment -0.0079 0.25 0.93 0.0038 0.259 0.96 1.3332 0.9998 SpOx1.1_003924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C09 compound treatment -0.0099 0.248 0.92 -0.0022 0.253 0.94 1.3122 0.9999 SpOx1.1_003925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C10 compound treatment -0.0099 0.248 0.92 0.0068 0.262 0.97 1.3359 0.9996 SpOx1.1_003926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C11 compound treatment 0.0011 0.259 0.96 -2.0E-4 0.255 0.95 1.3462 1.0 SpOx1.1_003927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C12 compound treatment -0.0019 0.256 0.95 -0.0082 0.247 0.92 1.3174 0.9999 SpOx1.1_003928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C13 compound treatment -0.0059 0.252 0.93 -0.0032 0.252 0.93 1.3201 1.0 SpOx1.1_003929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C14 compound treatment -0.0159 0.242 0.9 -0.0122 0.243 0.9 1.2703 1.0 SpOx1.1_003930 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C15 compound treatment -0.0119 0.246 0.91 -0.0072 0.248 0.92 1.294 1.0 SpOx1.1_003931 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C16 compound treatment -0.0069 0.251 0.93 -0.0092 0.246 0.91 1.3017 1.0 SpOx1.1_003932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C17 compound treatment 0.0041 0.262 0.97 0.0048 0.26 0.96 1.3672 1.0 SpOx1.1_003933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C18 compound treatment -0.0039 0.254 0.94 -0.0022 0.253 0.94 1.328 1.0 SpOx1.1_003934 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C19 compound treatment 0.0011 0.259 0.96 0.0058 0.261 0.97 1.3619 1.0 SpOx1.1_003935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C20 compound treatment -0.0079 0.25 0.93 -2.0E-4 0.255 0.95 1.3228 0.9999 SpOx1.1_003936 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C21 compound treatment -0.0139 0.244 0.9 0.0068 0.262 0.97 1.3253 0.9993 SpOx1.1_003937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C22 compound treatment -0.0069 0.251 0.93 -0.0062 0.249 0.92 1.3095 1.0 SpOx1.1_003938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C23 mock treatment -0.0099 0.248 0.92 -0.0152 0.24 0.89 1.2781 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 C24 mock treatment -0.5091 -0.251 -0.93 -0.5059 -0.251 -0.93 -1.3128 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D01 compound treatment -0.0119 0.246 0.91 -0.0112 0.244 0.9 1.2834 1.0 SpOx1.1_003939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D02 compound treatment -0.0029 0.255 0.94 0.0048 0.26 0.96 1.3489 0.9999 SpOx1.1_003940 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D03 compound treatment -0.0119 0.246 0.91 -0.0042 0.251 0.93 1.3017 0.9999 SpOx1.1_003941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D04 compound treatment -0.0289 0.229 0.85 0.0058 0.261 0.97 1.2836 0.9978 SpOx1.1_003942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D05 compound treatment -0.0359 0.222 0.82 -0.0222 0.233 0.86 1.1919 0.9997 SpOx1.1_003943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D06 compound treatment -0.0119 0.246 0.91 -0.0172 0.238 0.88 1.2677 0.9999 SpOx1.1_003944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D07 compound treatment -0.0129 0.245 0.91 -0.0162 0.239 0.89 1.2676 0.9999 SpOx1.1_003945 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D08 compound treatment -0.0059 0.252 0.93 0.0068 0.262 0.97 1.3463 0.9998 SpOx1.1_003946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D09 compound treatment -0.0119 0.246 0.91 -0.0132 0.242 0.9 1.2782 1.0 SpOx1.1_003947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D10 compound treatment -0.0219 0.236 0.87 -0.0132 0.242 0.9 1.2519 0.9999 SpOx1.1_003948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D11 compound treatment 0.0061 0.264 0.98 0.0038 0.259 0.96 1.3698 1.0 SpOx1.1_003949 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D12 compound treatment -0.0139 0.244 0.9 -2.0E-4 0.255 0.95 1.3071 0.9997 SpOx1.1_003950 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D13 compound treatment 0.0051 0.263 0.97 -0.0042 0.251 0.93 1.3461 0.9997 SpOx1.1_003951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D14 compound treatment -0.0059 0.252 0.93 0.0228 0.278 1.03 1.3882 0.9988 SpOx1.1_003952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D15 compound treatment -0.0199 0.238 0.88 -0.0152 0.24 0.89 1.252 1.0 SpOx1.1_003953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D16 compound treatment -0.0039 0.254 0.94 0.0098 0.265 0.98 1.3594 0.9998 SpOx1.1_003954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D17 compound treatment -0.0249 0.233 0.86 -2.0E-4 0.255 0.95 1.2783 0.999 SpOx1.1_003955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D18 compound treatment -0.0089 0.249 0.92 -0.0022 0.253 0.94 1.3149 1.0 SpOx1.1_003956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D19 compound treatment -0.0149 0.243 0.9 -0.0062 0.249 0.92 1.2887 0.9999 SpOx1.1_003957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D20 compound treatment 0.0011 0.259 0.96 -0.0062 0.249 0.92 1.3305 0.9998 SpOx1.1_003958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D21 compound treatment -0.0259 0.232 0.86 -0.0022 0.253 0.94 1.2704 0.999 SpOx1.1_003959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D22 compound treatment 0.0011 0.259 0.96 -0.0012 0.254 0.94 1.3436 1.0 SpOx1.1_003960 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D23 mock treatment -0.0069 0.251 0.93 0.0088 0.264 0.98 1.3488 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 D24 mock treatment -0.5101 -0.252 -0.93 -0.5039 -0.249 -0.92 -1.3101 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E01 compound treatment -0.0149 0.243 0.9 0.0038 0.259 0.96 1.315 0.9995 SpOx1.1_003961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E02 compound treatment 0.0051 0.263 0.97 0.0068 0.262 0.97 1.375 1.0 SpOx1.1_003962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E03 compound treatment 0.0051 0.263 0.97 -0.0042 0.251 0.93 1.3462 0.9997 SpOx1.1_003963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E04 compound treatment -0.0029 0.255 0.94 -0.0122 0.243 0.9 1.3042 0.9997 SpOx1.1_003964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E05 compound treatment 0.0011 0.259 0.96 0.0048 0.26 0.96 1.3593 1.0 SpOx1.1_003965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E06 compound treatment -0.0109 0.247 0.91 -0.0072 0.248 0.92 1.2965 1.0 SpOx1.1_003966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E07 compound treatment 1.0E-4 0.258 0.95 0.0078 0.263 0.97 1.3646 0.9999 SpOx1.1_003967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E08 compound treatment 0.0161 0.274 1.01 0.0108 0.266 0.99 1.4142 0.9999 SpOx1.1_003968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E09 compound treatment 0.0071 0.265 0.98 0.0038 0.259 0.96 1.3723 0.9999 SpOx1.1_003969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E10 compound treatment 0.0161 0.274 1.01 0.0168 0.272 1.01 1.43 1.0 SpOx1.1_003970 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E11 compound treatment -0.0139 0.244 0.9 0.0028 0.258 0.96 1.3148 0.9996 SpOx1.1_003971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E12 compound treatment 0.0071 0.265 0.98 -0.0042 0.251 0.93 1.3514 0.9997 SpOx1.1_003972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E13 compound treatment 0.0251 0.283 1.05 0.0168 0.272 1.01 1.4535 0.9998 SpOx1.1_003973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E14 compound treatment 0.0061 0.264 0.98 0.0168 0.272 1.01 1.4038 0.9999 SpOx1.1_003974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E15 compound treatment 0.0281 0.286 1.06 0.0038 0.259 0.96 1.4272 0.9988 SpOx1.1_003975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E16 compound treatment -0.0039 0.254 0.94 0.0068 0.262 0.97 1.3516 0.9999 SpOx1.1_003976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E17 compound treatment -0.0169 0.241 0.89 0.0198 0.275 1.02 1.3517 0.9978 SpOx1.1_003977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E18 compound treatment 0.0101 0.268 0.99 0.0188 0.274 1.02 1.4195 0.9999 SpOx1.1_003978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E19 compound treatment 0.0081 0.266 0.98 0.0158 0.271 1.0 1.4065 0.9999 SpOx1.1_003979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E20 compound treatment 0.0051 0.263 0.97 0.0118 0.267 0.99 1.3881 1.0 SpOx1.1_003980 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E21 compound treatment 0.0211 0.279 1.03 0.0178 0.273 1.01 1.4457 1.0 SpOx1.1_003981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E22 compound treatment 0.0191 0.277 1.03 0.0088 0.264 0.98 1.4168 0.9997 SpOx1.1_003982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E23 mock treatment 0.0091 0.267 0.99 0.0078 0.263 0.97 1.3881 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 E24 mock treatment -0.5091 -0.251 -0.93 -0.5029 -0.248 -0.92 -1.3049 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F01 compound treatment -0.0219 0.236 0.87 -0.0122 0.243 0.9 1.2546 0.9999 SpOx1.1_003983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F02 compound treatment 0.0021 0.26 0.96 -0.0042 0.251 0.93 1.3383 0.9999 SpOx1.1_003984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F03 compound treatment -0.0039 0.254 0.94 8.0E-4 0.256 0.95 1.3358 1.0 SpOx1.1_003985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F04 compound treatment -0.0259 0.232 0.86 -0.0052 0.25 0.93 1.2626 0.9993 SpOx1.1_003986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F05 compound treatment -0.0029 0.255 0.94 -0.0202 0.235 0.87 1.2833 0.9992 SpOx1.1_003987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F06 compound treatment 0.0041 0.262 0.97 0.0098 0.265 0.98 1.3803 1.0 SpOx1.1_003988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F07 compound treatment -0.0089 0.249 0.92 -0.0052 0.25 0.93 1.3071 1.0 SpOx1.1_003989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F08 compound treatment 0.0101 0.268 0.99 0.0138 0.269 1.0 1.4064 1.0 SpOx1.1_003990 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F09 compound treatment -0.0169 0.241 0.89 0.0128 0.268 0.99 1.3332 0.9986 SpOx1.1_003991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F10 compound treatment 0.0111 0.269 1.0 8.0E-4 0.256 0.95 1.3749 0.9997 SpOx1.1_003992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F11 compound treatment -0.0049 0.253 0.94 0.0018 0.257 0.95 1.3357 1.0 SpOx1.1_003993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F12 compound treatment 1.0E-4 0.258 0.95 -0.0052 0.25 0.93 1.3305 0.9999 SpOx1.1_003994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F13 compound treatment 0.0171 0.275 1.02 0.0098 0.265 0.98 1.4142 0.9998 SpOx1.1_003995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F14 compound treatment -0.0079 0.25 0.93 0.0048 0.26 0.96 1.3358 0.9998 SpOx1.1_003996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F15 compound treatment -0.0019 0.256 0.95 0.0208 0.276 1.02 1.3935 0.9993 SpOx1.1_003997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F16 compound treatment 0.0111 0.269 1.0 0.0158 0.271 1.0 1.4143 1.0 SpOx1.1_003998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F17 compound treatment -0.0089 0.249 0.92 -0.0072 0.248 0.92 1.3017 1.0 SpOx1.1_003999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F18 compound treatment -0.0109 0.247 0.91 0.0108 0.266 0.99 1.3438 0.9993 SpOx1.1_004000 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F19 compound treatment 0.0151 0.273 1.01 0.0068 0.262 0.97 1.4012 0.9998 SpOx1.1_004001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F20 compound treatment 0.0011 0.259 0.96 0.0058 0.261 0.97 1.362 1.0 SpOx1.1_004002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F21 compound treatment 0.0051 0.263 0.97 0.0128 0.268 0.99 1.3907 0.9999 SpOx1.1_004003 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F22 compound treatment 0.0021 0.26 0.96 0.0178 0.273 1.01 1.3961 0.9997 SpOx1.1_004004 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F23 mock treatment 0.0171 0.275 1.02 -0.0082 0.247 0.92 1.3671 0.9986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 F24 mock treatment -0.5101 -0.252 -0.93 -0.505 -0.25 -0.93 -1.313 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G01 compound treatment 0.0011 0.259 0.96 -0.0142 0.241 0.89 1.3094 0.9994 SpOx1.1_004005 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G02 compound treatment -0.0129 0.245 0.91 -0.0052 0.25 0.93 1.2966 0.9999 SpOx1.1_004006 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G03 compound treatment -0.0219 0.236 0.87 -0.0132 0.242 0.9 1.252 0.9999 SpOx1.1_004007 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G04 compound treatment -0.0069 0.251 0.93 -0.0142 0.241 0.89 1.2886 0.9998 SpOx1.1_004008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G05 compound treatment -0.0269 0.231 0.86 -0.0132 0.242 0.9 1.239 0.9997 SpOx1.1_004009 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G06 compound treatment -0.0139 0.244 0.9 -0.0062 0.249 0.92 1.2913 0.9999 SpOx1.1_004010 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G07 compound treatment 0.0101 0.268 0.99 8.0E-4 0.256 0.95 1.3724 0.9998 SpOx1.1_004011 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G08 compound treatment -0.0049 0.253 0.94 -0.0052 0.25 0.93 1.3174 1.0 SpOx1.1_004012 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G09 compound treatment -0.0099 0.248 0.92 -2.0E-4 0.255 0.95 1.3175 0.9999 SpOx1.1_004013 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G10 compound treatment -0.0069 0.251 0.93 0.0088 0.264 0.98 1.3489 0.9997 SpOx1.1_004014 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G11 compound treatment -0.0159 0.242 0.9 -0.0112 0.244 0.9 1.2729 1.0 SpOx1.1_004015 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G12 compound treatment -9.0E-4 0.257 0.95 0.0098 0.265 0.98 1.3672 0.9999 SpOx1.1_004016 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G13 compound treatment -0.0029 0.255 0.94 -0.0062 0.249 0.92 1.3199 0.9999 SpOx1.1_004017 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G14 compound treatment -0.0109 0.247 0.91 -0.0082 0.247 0.92 1.294 1.0 SpOx1.1_004018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G15 compound treatment 1.0E-4 0.258 0.95 0.0028 0.258 0.96 1.3515 1.0 SpOx1.1_004019 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G16 compound treatment -0.0139 0.244 0.9 -0.0182 0.237 0.88 1.2598 0.9999 SpOx1.1_004020 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G17 compound treatment 0.0011 0.259 0.96 -0.0082 0.247 0.92 1.3253 0.9997 SpOx1.1_004021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G18 compound treatment -0.0109 0.247 0.91 -0.0102 0.245 0.91 1.2887 1.0 SpOx1.1_004022 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G19 compound treatment -0.0049 0.253 0.94 -0.0172 0.238 0.88 1.286 0.9996 SpOx1.1_004023 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G20 compound treatment -0.0289 0.229 0.85 -0.0092 0.246 0.91 1.2442 0.9993 2142345 SpOx1.1_004024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G21 compound treatment -9.0E-4 0.257 0.95 -0.0122 0.243 0.9 1.3096 0.9996 SpOx1.1_004025 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G22 compound treatment -0.0179 0.24 0.89 -0.0062 0.249 0.92 1.2807 0.9998 SpOx1.1_004026 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G23 mock treatment -0.0059 0.252 0.93 -0.0022 0.253 0.94 1.3226 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 G24 mock treatment -0.5111 -0.253 -0.94 -0.5049 -0.25 -0.92 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H01 compound treatment -0.0179 0.24 0.89 -0.0152 0.24 0.89 1.2573 1.0 SpOx1.1_004027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H02 compound treatment -0.0269 0.231 0.86 0.0028 0.258 0.96 1.281 0.9984 SpOx1.1_004028 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H03 compound treatment -0.0129 0.245 0.91 -0.0972 0.158 0.59 1.0554 0.9776 SpOx1.1_004029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H04 compound treatment -0.0329 0.225 0.83 -0.0132 0.242 0.9 1.2234 0.9993 SpOx1.1_004030 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H05 compound treatment -0.0169 0.241 0.89 -0.0132 0.242 0.9 1.2651 1.0 SpOx1.1_004031 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H06 compound treatment -0.0049 0.253 0.94 -0.0032 0.252 0.93 1.3227 1.0 SpOx1.1_004032 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H07 compound treatment -0.0109 0.247 0.91 0.0058 0.261 0.97 1.3307 0.9996 2144713 SpOx1.1_004033 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H08 compound treatment -0.0209 0.237 0.88 -0.0142 0.241 0.89 1.2521 1.0 SpOx1.1_004034 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H09 compound treatment -0.0049 0.253 0.94 -0.0172 0.238 0.88 1.286 0.9996 SpOx1.1_004035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H10 compound treatment -0.0129 0.245 0.91 0.0078 0.263 0.97 1.3306 0.9993 SpOx1.1_004036 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H11 compound treatment -0.0199 0.238 0.88 -0.0012 0.254 0.94 1.2886 0.9994 SpOx1.1_004037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H12 compound treatment -0.0099 0.248 0.92 -0.0142 0.241 0.89 1.2808 0.9999 SpOx1.1_004038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H13 compound treatment -0.0029 0.255 0.94 -0.0192 0.236 0.87 1.286 0.9993 SpOx1.1_004039 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H14 compound treatment -0.0119 0.246 0.91 -0.0062 0.249 0.92 1.2965 1.0 SpOx1.1_004040 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H15 compound treatment -0.0079 0.25 0.93 -0.0032 0.252 0.93 1.3148 1.0 SpOx1.1_004041 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H16 compound treatment -0.0069 0.251 0.93 -0.0032 0.252 0.93 1.3175 1.0 SpOx1.1_004042 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H17 compound treatment -0.0029 0.255 0.94 -0.0112 0.244 0.9 1.3069 0.9998 SpOx1.1_004043 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H18 compound treatment -0.0199 0.238 0.88 -0.0162 0.239 0.89 1.2493 1.0 SpOx1.1_004044 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H19 compound treatment -0.0139 0.244 0.9 -0.0122 0.243 0.9 1.2756 1.0 SpOx1.1_004045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H20 compound treatment -0.0079 0.25 0.93 -0.0062 0.249 0.92 1.3069 1.0 SpOx1.1_004046 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H21 compound treatment -0.0159 0.242 0.9 -0.0082 0.247 0.92 1.2808 0.9999 SpOx1.1_004047 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H22 compound treatment -0.0059 0.252 0.93 0.0068 0.262 0.97 1.3463 0.9998 SpOx1.1_004048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H23 mock treatment -0.0129 0.245 0.91 0.0128 0.268 0.99 1.3436 0.999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 H24 mock treatment -0.5101 -0.252 -0.93 -0.5059 -0.251 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I01 compound treatment 0.0031 0.261 0.97 -0.0022 0.253 0.94 1.3461 0.9999 SpOx1.1_004049 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I02 compound treatment -0.0099 0.248 0.92 0.0028 0.258 0.96 1.3254 0.9998 SpOx1.1_004050 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I03 compound treatment 0.0061 0.264 0.98 -0.0052 0.25 0.93 1.3461 0.9997 SpOx1.1_004051 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I04 compound treatment -0.0199 0.238 0.88 -0.0172 0.238 0.88 1.2468 1.0 SpOx1.1_004052 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I05 compound treatment -0.0149 0.243 0.9 0.0048 0.26 0.96 1.3175 0.9994 SpOx1.1_004053 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I06 compound treatment -0.0289 0.229 0.85 -0.0212 0.234 0.87 1.2128 0.9999 SpOx1.1_004054 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I07 compound treatment -0.0169 0.241 0.89 -0.0042 0.251 0.93 1.2887 0.9998 SpOx1.1_004055 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I08 compound treatment -0.0179 0.24 0.89 -0.0232 0.232 0.86 1.2364 0.9999 SpOx1.1_004056 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I09 compound treatment 0.0031 0.261 0.97 -0.0202 0.235 0.87 1.299 0.9987 SpOx1.1_004057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I10 compound treatment 0.0031 0.261 0.97 0.0118 0.267 0.99 1.3829 0.9999 SpOx1.1_004058 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I11 compound treatment -0.0159 0.242 0.9 0.0028 0.258 0.96 1.3097 0.9995 SpOx1.1_004059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I12 compound treatment -0.0109 0.247 0.91 -0.0102 0.245 0.91 1.2885 1.0 SpOx1.1_004060 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I13 compound treatment -0.0019 0.256 0.95 -0.0132 0.242 0.9 1.3043 0.9996 SpOx1.1_004061 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I14 compound treatment -0.0129 0.245 0.91 -0.0092 0.246 0.91 1.2861 1.0 SpOx1.1_004062 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I15 compound treatment -0.0229 0.235 0.87 -0.0092 0.246 0.91 1.2598 0.9997 SpOx1.1_004063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I16 compound treatment -0.0379 0.22 0.81 -0.0232 0.232 0.86 1.184 0.9996 SpOx1.1_004064 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I17 compound treatment 0.0061 0.264 0.98 -0.0162 0.239 0.89 1.3173 0.9988 SpOx1.1_004065 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I18 compound treatment 0.0041 0.262 0.97 -0.0172 0.238 0.88 1.3095 0.9989 SpOx1.1_004066 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I19 compound treatment -0.0149 0.243 0.9 0.0028 0.258 0.96 1.3123 0.9995 SpOx1.1_004067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I20 compound treatment -0.0129 0.245 0.91 -0.0152 0.24 0.89 1.2703 1.0 SpOx1.1_004068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I21 compound treatment 0.0041 0.262 0.97 -0.0192 0.236 0.87 1.3043 0.9987 SpOx1.1_004069 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I22 compound treatment -0.0099 0.248 0.92 -0.0012 0.254 0.94 1.3149 0.9999 SpOx1.1_004070 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I23 mock treatment 0.0071 0.265 0.98 0.0028 0.258 0.96 1.3697 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 I24 mock treatment -0.5111 -0.253 -0.94 -0.5049 -0.25 -0.92 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J01 compound treatment -0.0199 0.238 0.88 -0.0192 0.236 0.87 1.2415 1.0 SpOx1.1_004071 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J02 compound treatment -0.0559 0.202 0.75 -0.0222 0.233 0.86 1.1395 0.9974 2143289 SpOx1.1_004072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J03 compound treatment -0.0249 0.233 0.86 -0.0302 0.225 0.83 1.1996 0.9999 SpOx1.1_004073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J04 compound treatment -0.0139 0.244 0.9 -0.0062 0.249 0.92 1.2913 0.9999 SpOx1.1_004074 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J05 compound treatment -0.0279 0.23 0.85 -0.0152 0.24 0.89 1.2311 0.9998 SpOx1.1_004075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J06 compound treatment -0.0189 0.239 0.88 -2.0E-4 0.255 0.95 1.294 0.9995 SpOx1.1_004076 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J07 compound treatment -0.0169 0.241 0.89 -0.0272 0.228 0.85 1.2284 0.9996 SpOx1.1_004077 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J08 compound treatment -0.0059 0.252 0.93 -0.0162 0.239 0.89 1.286 0.9997 SpOx1.1_004078 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J09 compound treatment -0.0149 0.243 0.9 -0.0192 0.236 0.87 1.2546 0.9999 SpOx1.1_004079 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J10 compound treatment -0.0409 0.217 0.8 -0.0352 0.22 0.82 1.1448 1.0 SpOx1.1_004080 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J11 compound treatment -0.0189 0.239 0.88 -0.0122 0.243 0.9 1.2624 1.0 2144733 SpOx1.1_004081 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J12 compound treatment -0.0159 0.242 0.9 -0.0062 0.249 0.92 1.2861 0.9999 SpOx1.1_004082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J13 compound treatment -0.0379 0.22 0.81 -0.0112 0.244 0.9 1.2153 0.9986 SpOx1.1_004083 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J14 compound treatment -0.0189 0.239 0.88 -0.0082 0.247 0.92 1.273 0.9999 2144725 SpOx1.1_004084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J15 compound treatment -0.0049 0.253 0.94 -0.0212 0.234 0.87 1.2755 0.9993 SpOx1.1_004085 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J16 compound treatment -0.0199 0.238 0.88 -0.0202 0.235 0.87 1.2389 1.0 SpOx1.1_004086 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J17 compound treatment 0.0021 0.26 0.96 -0.0192 0.236 0.87 1.2991 0.9989 SpOx1.1_004087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J18 compound treatment -0.0169 0.241 0.89 -0.0062 0.249 0.92 1.2833 0.9999 SpOx1.1_004088 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J19 compound treatment 0.0051 0.263 0.97 -0.0062 0.249 0.92 1.3409 0.9996 SpOx1.1_004089 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J20 compound treatment 0.0021 0.26 0.96 -0.0072 0.248 0.92 1.3304 0.9997 SpOx1.1_004090 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J21 compound treatment -0.0209 0.237 0.88 -0.0152 0.24 0.89 1.2494 1.0 SpOx1.1_004091 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J22 compound treatment 1.0E-4 0.258 0.95 -0.0162 0.239 0.89 1.3017 0.9993 SpOx1.1_004092 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J23 mock treatment -0.0119 0.246 0.91 -0.0152 0.24 0.89 1.2729 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 J24 mock treatment -0.5121 -0.254 -0.94 -0.5049 -0.25 -0.92 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K01 compound treatment 0.0031 0.261 0.97 -2.0E-4 0.255 0.95 1.3514 0.9999 SpOx1.1_004093 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K02 compound treatment -0.0459 0.212 0.78 -0.0432 0.212 0.79 1.1107 1.0 SpOx1.1_004094 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K03 compound treatment -0.0019 0.256 0.95 -0.0082 0.247 0.92 1.3174 0.9999 2144737 SpOx1.1_004095 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K04 compound treatment -0.0149 0.243 0.9 -0.0072 0.248 0.92 1.2861 0.9999 SpOx1.1_004096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K05 compound treatment -0.0119 0.246 0.91 -0.0042 0.251 0.93 1.3018 0.9999 SpOx1.1_004097 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K06 compound treatment 1.0E-4 0.258 0.95 -0.0032 0.252 0.93 1.3357 0.9999 SpOx1.1_004098 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K07 compound treatment -0.0469 0.211 0.78 -0.0022 0.253 0.94 1.2155 0.9959 SpOx1.1_004099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K08 compound treatment -0.0149 0.243 0.9 0.0028 0.258 0.96 1.3122 0.9995 SpOx1.1_004100 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K09 compound treatment -0.0249 0.233 0.86 -0.0182 0.237 0.88 1.2312 1.0 SpOx1.1_004101 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K10 compound treatment -0.0149 0.243 0.9 -0.0132 0.242 0.9 1.2703 1.0 SpOx1.1_004102 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K11 compound treatment -0.0139 0.244 0.9 -0.0132 0.242 0.9 1.273 1.0 SpOx1.1_004103 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K12 compound treatment -0.0289 0.229 0.85 -0.0072 0.248 0.92 1.2495 0.9992 SpOx1.1_004104 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K13 compound treatment -0.0349 0.223 0.83 -0.0142 0.241 0.89 1.2153 0.9992 SpOx1.1_004105 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K14 compound treatment -0.0079 0.25 0.93 -0.0142 0.241 0.89 1.286 0.9998 SpOx1.1_004106 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K15 compound treatment 0.0011 0.259 0.96 -2.0E-4 0.255 0.95 1.3462 1.0 SpOx1.1_004107 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K16 compound treatment -0.0029 0.255 0.94 0.0038 0.259 0.96 1.3463 1.0 SpOx1.1_004108 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K17 compound treatment -0.0189 0.239 0.88 -0.0132 0.242 0.9 1.2597 1.0 SpOx1.1_004109 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K18 compound treatment -0.0089 0.249 0.92 -0.0272 0.228 0.85 1.2494 0.9991 SpOx1.1_004110 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K19 compound treatment -0.0109 0.247 0.91 -0.0232 0.232 0.86 1.2546 0.9995 SpOx1.1_004111 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K20 compound treatment -0.0149 0.243 0.9 -0.0042 0.251 0.93 1.2938 0.9999 SpOx1.1_004112 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K21 compound treatment -0.0149 0.243 0.9 -0.0272 0.228 0.85 1.2337 0.9995 SpOx1.1_004113 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K22 compound treatment 0.0081 0.266 0.98 0.0108 0.266 0.99 1.3933 1.0 SpOx1.1_004114 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K23 mock treatment -0.0049 0.253 0.94 -0.0012 0.254 0.94 1.3278 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 K24 mock treatment -0.5101 -0.252 -0.93 -0.5059 -0.251 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L01 compound treatment -0.0259 0.232 0.86 -0.0032 0.252 0.93 1.2679 0.9991 SpOx1.1_004115 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L02 compound treatment -0.0019 0.256 0.95 0.0088 0.264 0.98 1.362 0.9999 SpOx1.1_004116 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L03 compound treatment -0.0079 0.25 0.93 0.0058 0.261 0.97 1.3385 0.9998 SpOx1.1_004117 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L04 compound treatment 0.0081 0.266 0.98 0.0088 0.264 0.98 1.3881 1.0 SpOx1.1_004118 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L05 compound treatment -0.0079 0.25 0.93 0.0088 0.264 0.98 1.3463 0.9996 SpOx1.1_004119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L06 compound treatment 0.0111 0.269 1.0 -0.0152 0.24 0.89 1.3331 0.9984 SpOx1.1_004120 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L07 compound treatment -0.0049 0.253 0.94 -0.0102 0.245 0.91 1.3043 0.9999 SpOx1.1_004121 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L08 compound treatment -0.0049 0.253 0.94 -0.0082 0.247 0.92 1.3096 0.9999 SpOx1.1_004122 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L09 compound treatment 0.0111 0.269 1.0 0.0068 0.262 0.97 1.3907 0.9999 SpOx1.1_004123 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L10 compound treatment -0.0149 0.243 0.9 0.0048 0.26 0.96 1.3175 0.9994 SpOx1.1_004124 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L11 compound treatment 1.0E-4 0.258 0.95 0.0148 0.27 1.0 1.3829 0.9997 SpOx1.1_004125 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L12 compound treatment 0.0081 0.266 0.98 0.0078 0.263 0.97 1.3855 1.0 2142609 SpOx1.1_004126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L13 compound treatment -0.0029 0.255 0.94 -0.0022 0.253 0.94 1.3305 1.0 SpOx1.1_004127 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L14 compound treatment -0.0209 0.237 0.88 0.0028 0.258 0.96 1.2966 0.9991 SpOx1.1_004128 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L15 compound treatment 0.0081 0.266 0.98 0.0018 0.257 0.95 1.3697 0.9999 SpOx1.1_004129 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L16 compound treatment -0.0059 0.252 0.93 0.0048 0.26 0.96 1.3411 0.9999 SpOx1.1_004130 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L17 compound treatment 0.0021 0.26 0.96 0.0158 0.271 1.0 1.3908 0.9998 SpOx1.1_004131 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L18 compound treatment 0.0111 0.269 1.0 0.0048 0.26 0.96 1.3855 0.9999 SpOx1.1_004132 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L19 compound treatment 0.0021 0.26 0.96 0.0058 0.261 0.97 1.3646 1.0 SpOx1.1_004133 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L20 compound treatment 0.0071 0.265 0.98 0.0058 0.261 0.97 1.3776 1.0 SpOx1.1_004134 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L21 compound treatment -0.0099 0.248 0.92 0.0118 0.267 0.99 1.349 0.9993 SpOx1.1_004135 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L22 compound treatment 0.0171 0.275 1.02 0.0168 0.272 1.01 1.4326 1.0 SpOx1.1_004136 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L23 mock treatment 0.0121 0.27 1.0 0.0158 0.271 1.0 1.4169 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 L24 mock treatment -0.5111 -0.253 -0.94 -0.507 -0.252 -0.93 -1.3209 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M01 compound treatment -0.0109 0.247 0.91 0.0038 0.259 0.96 1.3253 0.9997 SpOx1.1_004137 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M02 compound treatment 0.0051 0.263 0.97 -0.0032 0.252 0.93 1.3488 0.9998 SpOx1.1_004138 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M03 compound treatment -9.0E-4 0.257 0.95 0.0078 0.263 0.97 1.362 0.9999 SpOx1.1_004139 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M04 compound treatment -0.0039 0.254 0.94 -0.0072 0.248 0.92 1.3148 0.9999 SpOx1.1_004140 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M05 compound treatment 0.0051 0.263 0.97 0.0058 0.261 0.97 1.3724 1.0 SpOx1.1_004141 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M06 compound treatment 0.0041 0.262 0.97 8.0E-4 0.256 0.95 1.3567 0.9999 SpOx1.1_004142 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M07 compound treatment 0.0021 0.26 0.96 0.0058 0.261 0.97 1.3645 1.0 SpOx1.1_004143 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M08 compound treatment 0.0041 0.262 0.97 -0.0022 0.253 0.94 1.3488 0.9999 SpOx1.1_004144 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M09 compound treatment -0.0079 0.25 0.93 -2.0E-4 0.255 0.95 1.3227 0.9999 SpOx1.1_004145 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M10 compound treatment -0.0139 0.244 0.9 -0.0112 0.244 0.9 1.2781 1.0 SpOx1.1_004146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M11 compound treatment 1.0E-4 0.258 0.95 -0.0072 0.248 0.92 1.3253 0.9998 SpOx1.1_004147 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M12 compound treatment -0.0019 0.256 0.95 -0.0132 0.242 0.9 1.3043 0.9996 SpOx1.1_004148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M13 compound treatment -0.0269 0.231 0.86 -0.0262 0.229 0.85 1.205 1.0 SpOx1.1_004149 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M14 compound treatment -0.0029 0.255 0.94 0.0108 0.266 0.99 1.3646 0.9998 SpOx1.1_004150 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M15 compound treatment -0.0039 0.254 0.94 -0.0192 0.236 0.87 1.2833 0.9994 SpOx1.1_004151 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M16 compound treatment -0.0209 0.237 0.88 -0.0452 0.21 0.78 1.1709 0.9982 SpOx1.1_004152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M17 compound treatment -0.0089 0.249 0.92 0.0068 0.262 0.97 1.3384 0.9997 SpOx1.1_004153 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M18 compound treatment -0.0029 0.255 0.94 0.0058 0.261 0.97 1.3515 0.9999 SpOx1.1_004154 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M19 compound treatment 0.0081 0.266 0.98 -0.0032 0.252 0.93 1.3567 0.9997 SpOx1.1_004155 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M20 compound treatment -0.0089 0.249 0.92 -2.0E-4 0.255 0.95 1.3202 0.9999 SpOx1.1_004156 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M21 compound treatment -0.0019 0.256 0.95 -0.0022 0.253 0.94 1.3332 1.0 SpOx1.1_004157 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M22 compound treatment 0.0031 0.261 0.97 0.0058 0.261 0.97 1.3672 1.0 SpOx1.1_004158 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M23 mock treatment 0.0081 0.266 0.98 0.0018 0.257 0.95 1.3696 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 M24 mock treatment -0.5111 -0.253 -0.94 -0.5069 -0.252 -0.93 -1.3206 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N01 compound treatment -0.0289 0.229 0.85 -0.0022 0.253 0.94 1.2626 0.9987 SpOx1.1_004159 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N02 compound treatment -0.0269 0.231 0.85 -0.0152 0.24 0.89 1.2336 0.9998 SpOx1.1_004160 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N03 compound treatment -0.0099 0.248 0.92 -0.0322 0.223 0.83 1.2335 0.9986 SpOx1.1_004161 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N04 compound treatment -0.0219 0.236 0.87 -0.0192 0.236 0.87 1.2363 1.0 SpOx1.1_004162 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N05 compound treatment -0.0059 0.252 0.93 -0.0022 0.253 0.94 1.3227 1.0 SpOx1.1_004163 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N06 compound treatment -0.0149 0.243 0.9 -0.0112 0.244 0.9 1.2757 1.0 SpOx1.1_004164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N07 compound treatment -0.0349 0.223 0.83 -0.0082 0.247 0.92 1.2311 0.9987 SpOx1.1_004165 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N08 compound treatment -0.0389 0.219 0.81 -0.0122 0.243 0.9 1.2102 0.9986 SpOx1.1_004166 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N09 compound treatment -0.0469 0.211 0.78 -0.0272 0.228 0.85 1.15 0.9992 SpOx1.1_004167 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N10 compound treatment -0.0069 0.251 0.93 -0.0042 0.251 0.93 1.3149 1.0 SpOx1.1_004168 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N11 compound treatment -0.0299 0.228 0.84 -0.0172 0.238 0.88 1.2206 0.9998 SpOx1.1_004169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N12 compound treatment -0.0059 0.252 0.93 -0.0112 0.244 0.9 1.2991 0.9999 SpOx1.1_004170 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N13 compound treatment -0.0189 0.239 0.88 -0.0262 0.229 0.85 1.2258 0.9998 SpOx1.1_004171 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N14 compound treatment -9.0E-4 0.257 0.95 -0.0162 0.239 0.89 1.2991 0.9994 SpOx1.1_004172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N15 compound treatment -0.0299 0.228 0.84 -2.0E-4 0.255 0.95 1.2652 0.9984 SpOx1.1_004173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N16 compound treatment -0.0029 0.255 0.94 -0.0042 0.251 0.93 1.3253 1.0 SpOx1.1_004174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N17 compound treatment -0.0159 0.242 0.9 -0.0222 0.233 0.86 1.2441 0.9998 SpOx1.1_004175 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N18 compound treatment -0.0189 0.239 0.88 -0.0202 0.235 0.87 1.2415 1.0 SpOx1.1_004176 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N19 compound treatment -0.0149 0.243 0.9 -0.0112 0.244 0.9 1.2756 1.0 SpOx1.1_004177 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N20 compound treatment -0.0199 0.238 0.88 -0.0122 0.243 0.9 1.26 0.9999 SpOx1.1_004178 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N21 compound treatment 0.0111 0.269 1.0 0.0068 0.262 0.97 1.3907 0.9999 SpOx1.1_004179 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N22 compound treatment -0.0059 0.252 0.93 -0.0012 0.254 0.94 1.3254 1.0 SpOx1.1_004180 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N23 mock treatment 0.0021 0.26 0.96 0.0028 0.258 0.96 1.3567 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 N24 mock treatment -0.5111 -0.253 -0.94 -0.5069 -0.252 -0.93 -1.3206 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O01 compound treatment -0.0129 0.245 0.91 -0.0032 0.252 0.93 1.3018 0.9999 SpOx1.1_004181 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O02 compound treatment 0.0081 0.266 0.98 0.0018 0.257 0.95 1.3698 0.9999 SpOx1.1_004182 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O03 compound treatment -0.0079 0.25 0.93 -0.0112 0.244 0.9 1.2938 0.9999 SpOx1.1_004183 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O04 compound treatment -0.0039 0.254 0.94 -0.0112 0.244 0.9 1.3043 0.9998 SpOx1.1_004184 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O05 compound treatment 0.0011 0.259 0.96 -0.0032 0.252 0.93 1.3384 0.9999 SpOx1.1_004185 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O06 compound treatment 0.0061 0.264 0.98 -0.0052 0.25 0.93 1.3462 0.9997 SpOx1.1_004186 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O07 compound treatment -0.0119 0.246 0.91 0.0018 0.257 0.95 1.3176 0.9997 SpOx1.1_004187 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O08 compound treatment 0.0011 0.259 0.96 -0.0082 0.247 0.92 1.3253 0.9997 SpOx1.1_004188 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O09 compound treatment -0.0039 0.254 0.94 -0.0032 0.252 0.93 1.3253 1.0 SpOx1.1_004189 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O10 compound treatment -0.0149 0.243 0.9 -0.0172 0.238 0.88 1.2599 1.0 SpOx1.1_004190 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O11 compound treatment -0.0189 0.239 0.88 -0.0202 0.235 0.87 1.2415 1.0 SpOx1.1_004191 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O12 compound treatment -0.0089 0.249 0.92 -0.0202 0.235 0.87 1.2676 0.9996 SpOx1.1_004192 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O13 compound treatment -0.0299 0.228 0.84 -0.0092 0.246 0.91 1.2417 0.9993 SpOx1.1_004193 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O14 compound treatment -0.0049 0.253 0.94 -2.0E-4 0.255 0.95 1.3305 1.0 SpOx1.1_004194 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O15 compound treatment 0.0141 0.272 1.01 -2.0E-4 0.255 0.95 1.3802 0.9995 SpOx1.1_004195 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O16 compound treatment -0.0109 0.247 0.91 0.0068 0.262 0.97 1.3333 0.9995 SpOx1.1_004196 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O17 compound treatment 0.0011 0.259 0.96 0.0038 0.259 0.96 1.3567 1.0 SpOx1.1_004197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O18 compound treatment 0.0051 0.263 0.97 -0.0112 0.244 0.9 1.3279 0.9993 SpOx1.1_004198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O19 compound treatment -0.0109 0.247 0.91 -0.0092 0.246 0.91 1.2912 1.0 SpOx1.1_004199 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O20 compound treatment -0.0259 0.232 0.86 -0.0192 0.236 0.87 1.2259 1.0 SpOx1.1_004200 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O21 compound treatment 0.0101 0.268 0.99 -0.0012 0.254 0.94 1.367 0.9997 SpOx1.1_004201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O22 compound treatment 0.0081 0.266 0.98 8.0E-4 0.256 0.95 1.3672 0.9998 SpOx1.1_004202 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O23 mock treatment 0.0111 0.269 1.0 -0.0022 0.253 0.94 1.367 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 O24 mock treatment -0.5111 -0.253 -0.94 -0.5059 -0.251 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P01 compound treatment -0.0469 0.211 0.78 -0.0152 0.24 0.89 1.1813 0.9979 SpOx1.1_004203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P02 compound treatment -0.0149 0.243 0.9 -0.0072 0.248 0.92 1.286 0.9999 SpOx1.1_004204 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P03 compound treatment -0.0239 0.234 0.87 -0.0052 0.25 0.93 1.2677 0.9994 SpOx1.1_004205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P04 compound treatment -0.0179 0.24 0.89 -0.0202 0.235 0.87 1.2441 1.0 SpOx1.1_004206 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P05 compound treatment -0.0179 0.24 0.89 -0.0252 0.23 0.85 1.231 0.9998 SpOx1.1_004207 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P06 compound treatment -0.0029 0.255 0.94 -0.0202 0.235 0.87 1.2833 0.9992 SpOx1.1_004208 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P07 compound treatment -0.0429 0.215 0.8 -0.0302 0.225 0.83 1.1525 0.9997 SpOx1.1_004209 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P08 compound treatment -0.0239 0.234 0.87 -0.0102 0.245 0.91 1.2546 0.9997 SpOx1.1_004210 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P09 compound treatment -0.0489 0.209 0.77 -0.0582 0.197 0.73 1.0635 0.9996 SpOx1.1_004211 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P10 compound treatment -0.0249 0.233 0.86 -0.0532 0.202 0.75 1.1394 0.9975 SpOx1.1_004212 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P11 compound treatment -0.0429 0.215 0.8 -0.0452 0.21 0.78 1.1133 0.9999 SpOx1.1_004213 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P12 compound treatment -0.0279 0.23 0.85 -0.0192 0.236 0.87 1.2205 0.9999 SpOx1.1_004214 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P13 compound treatment -0.0239 0.234 0.87 -0.0302 0.225 0.83 1.2023 0.9998 SpOx1.1_004215 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P14 compound treatment -0.0189 0.239 0.88 -0.0212 0.234 0.87 1.2389 1.0 SpOx1.1_004216 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P15 compound treatment -0.0289 0.229 0.85 -0.0152 0.24 0.89 1.2284 0.9997 SpOx1.1_004217 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P16 compound treatment -0.0259 0.232 0.86 -0.0262 0.229 0.85 1.2074 1.0 SpOx1.1_004218 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P17 compound treatment -0.0159 0.242 0.9 -0.0302 0.225 0.83 1.2231 0.9994 SpOx1.1_004219 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P18 compound treatment -0.0319 0.226 0.84 -0.0092 0.246 0.91 1.2363 0.9991 SpOx1.1_004220 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P19 compound treatment -0.0209 0.237 0.88 -0.0122 0.243 0.9 1.2572 0.9999 SpOx1.1_004221 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P20 compound treatment -0.0129 0.245 0.91 -0.0142 0.241 0.89 1.2729 1.0 SpOx1.1_004222 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P21 compound treatment -0.0189 0.239 0.88 -0.0032 0.252 0.93 1.2861 0.9996 SpOx1.1_004223 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P22 compound treatment -0.0239 0.234 0.87 -0.0112 0.244 0.9 1.2519 0.9998 SpOx1.1_004224 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P23 mock treatment -0.0359 0.222 0.82 -0.0032 0.252 0.93 1.2415 0.998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1289 P24 mock treatment -0.5121 -0.254 -0.94 -0.5069 -0.252 -0.93 -1.3232 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A01 compound treatment -0.1023 0.155 0.57 -0.0775 0.179 0.66 0.8734 0.9973 SpOx1.1_004225 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A02 compound treatment -0.0954 0.162 0.6 -0.0705 0.186 0.69 0.9098 0.9975 SpOx1.1_004226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A03 compound treatment -0.0844 0.173 0.64 -0.1006 0.156 0.58 0.8597 0.9987 SpOx1.1_004227 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A04 compound treatment -0.0983 0.159 0.59 -0.1006 0.156 0.58 0.8233 1.0 SpOx1.1_004228 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A05 compound treatment -0.0944 0.163 0.6 -0.0815 0.175 0.65 0.8835 0.9993 SpOx1.1_004229 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A06 compound treatment -0.1033 0.154 0.57 -0.0966 0.16 0.59 0.8207 0.9998 SpOx1.1_004230 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A07 compound treatment -0.0724 0.185 0.68 -0.0966 0.16 0.59 0.9015 0.9975 SpOx1.1_004231 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A08 compound treatment -0.0944 0.163 0.6 -0.0805 0.176 0.65 0.8861 0.9992 SpOx1.1_004232 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A09 compound treatment -0.1103 0.147 0.54 -0.0565 0.2 0.74 0.9074 0.9883 SpOx1.1_004233 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A10 compound treatment -0.0974 0.16 0.59 -0.0875 0.169 0.63 0.86 0.9996 SpOx1.1_004234 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A11 compound treatment -0.0894 0.168 0.62 -0.0725 0.184 0.68 0.9202 0.9989 SpOx1.1_004235 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A12 compound treatment -0.0874 0.17 0.63 -0.0705 0.186 0.69 0.9307 0.9989 SpOx1.1_004236 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A13 compound treatment -0.0934 0.164 0.61 -0.0785 0.178 0.66 0.894 0.9991 SpOx1.1_004237 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A14 compound treatment -0.0973 0.16 0.59 -0.0825 0.174 0.64 0.8734 0.9991 SpOx1.1_004238 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A15 compound treatment -0.0854 0.172 0.63 -0.0735 0.183 0.68 0.928 0.9995 SpOx1.1_004239 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A16 compound treatment -0.0924 0.165 0.61 -0.0775 0.179 0.66 0.8993 0.9991 SpOx1.1_004240 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A17 compound treatment -0.0864 0.171 0.63 -0.0815 0.175 0.65 0.9045 0.9999 SpOx1.1_004241 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A18 compound treatment -0.0894 0.168 0.62 -0.0845 0.172 0.64 0.8888 0.9999 SpOx1.1_004242 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A19 compound treatment -0.0944 0.163 0.6 -0.0805 0.176 0.65 0.8862 0.9992 SpOx1.1_004243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A20 compound treatment -0.0844 0.173 0.64 -0.0735 0.183 0.68 0.9306 0.9996 SpOx1.1_004244 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A21 compound treatment -0.0993 0.158 0.58 -0.0575 0.199 0.74 0.9336 0.9933 SpOx1.1_004245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A22 compound treatment -0.0903 0.167 0.62 -0.0775 0.179 0.66 0.9048 0.9994 SpOx1.1_004246 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A23 mock treatment -0.0814 0.176 0.65 -0.0695 0.187 0.69 0.949 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 A24 mock treatment -0.5081 -0.251 -0.93 -0.5069 -0.251 -0.93 -1.3128 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B01 compound treatment -0.0214 0.236 0.87 0.0016 0.258 0.96 1.292 0.9989 SpOx1.1_004247 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B02 compound treatment -0.0054 0.252 0.93 -0.0064 0.25 0.93 1.3129 1.0 2144697 SpOx1.1_004248 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B03 compound treatment 0.0056 0.263 0.97 0.0135 0.27 1.0 1.3939 0.9999 SpOx1.1_004249 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B04 compound treatment 0.0066 0.264 0.97 -0.0024 0.254 0.94 1.3547 0.9998 SpOx1.1_004250 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B05 compound treatment 0.0056 0.263 0.97 0.0016 0.258 0.96 1.3626 1.0 SpOx1.1_004251 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B06 compound treatment -0.0144 0.243 0.9 -0.0044 0.252 0.93 1.2946 0.9998 SpOx1.1_004252 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B07 compound treatment -0.0034 0.254 0.94 -0.0064 0.25 0.93 1.3182 1.0 SpOx1.1_004253 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B08 compound treatment 0.0126 0.27 1.0 0.0135 0.27 1.0 1.4123 1.0 SpOx1.1_004254 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B09 compound treatment -0.0054 0.252 0.93 0.0105 0.267 0.99 1.3574 0.9995 SpOx1.1_004255 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B10 compound treatment -4.0E-4 0.257 0.95 0.0105 0.267 0.99 1.3705 0.9998 SpOx1.1_004256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B11 compound treatment -0.0014 0.256 0.95 0.0036 0.26 0.96 1.3496 1.0 SpOx1.1_004257 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B12 compound treatment -0.0064 0.251 0.93 0.0025 0.259 0.96 1.3338 0.9999 SpOx1.1_004258 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B13 compound treatment 0.0016 0.259 0.96 0.0205 0.277 1.03 1.4019 0.9994 SpOx1.1_004259 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B14 compound treatment 0.0116 0.269 0.99 0.0046 0.261 0.97 1.3861 0.9999 SpOx1.1_004260 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B15 compound treatment -0.0024 0.255 0.94 0.0046 0.261 0.97 1.3496 0.9999 SpOx1.1_004261 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B16 compound treatment 0.0016 0.259 0.96 0.0036 0.26 0.96 1.3574 1.0 SpOx1.1_004262 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B17 compound treatment 0.0126 0.27 1.0 0.0105 0.267 0.99 1.4044 1.0 SpOx1.1_004263 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B18 compound treatment 0.0036 0.261 0.96 0.0055 0.262 0.97 1.3677 1.0 SpOx1.1_004264 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B19 compound treatment 0.0066 0.264 0.98 0.0155 0.272 1.01 1.4019 0.9999 SpOx1.1_004265 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B20 compound treatment 0.0036 0.261 0.96 0.0135 0.27 1.0 1.3888 0.9998 SpOx1.1_004266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B21 compound treatment 0.0036 0.261 0.96 0.0215 0.278 1.03 1.4097 0.9995 SpOx1.1_004267 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B22 compound treatment -0.0054 0.252 0.93 -0.0024 0.254 0.94 1.3234 1.0 SpOx1.1_004268 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B23 mock treatment 0.0136 0.271 1.0 0.0036 0.26 0.96 1.3887 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 B24 mock treatment -0.5081 -0.251 -0.93 -0.5069 -0.251 -0.93 -1.3128 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C01 compound treatment -0.0134 0.244 0.9 -0.0054 0.251 0.93 1.2946 0.9999 SpOx1.1_004269 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C02 compound treatment -0.0084 0.249 0.92 -0.0145 0.242 0.9 1.284 0.9999 SpOx1.1_004270 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C03 compound treatment -0.0144 0.243 0.9 -0.0054 0.251 0.93 1.2919 0.9998 SpOx1.1_004271 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C04 compound treatment -0.0064 0.251 0.93 -0.0195 0.237 0.88 1.2762 0.9996 SpOx1.1_004272 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C05 compound treatment 0.0046 0.262 0.97 -0.0195 0.237 0.88 1.3049 0.9988 SpOx1.1_004273 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C06 compound treatment -0.0174 0.24 0.89 -0.0054 0.251 0.93 1.2841 0.9997 SpOx1.1_004274 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C07 compound treatment -0.0154 0.242 0.89 0.0036 0.26 0.96 1.313 0.9993 SpOx1.1_004275 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C08 compound treatment -0.0034 0.254 0.94 0.0056 0.262 0.97 1.3496 0.9999 SpOx1.1_004276 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C09 compound treatment -0.0104 0.247 0.91 0.0016 0.258 0.96 1.3208 0.9997 SpOx1.1_004277 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C10 compound treatment -0.0154 0.242 0.89 0.0035 0.26 0.96 1.3128 0.9993 SpOx1.1_004278 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C11 compound treatment -0.0064 0.251 0.93 -0.0014 0.255 0.94 1.3234 1.0 SpOx1.1_004279 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C12 compound treatment -4.0E-4 0.257 0.95 0.0026 0.259 0.96 1.3496 1.0 SpOx1.1_004280 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C13 compound treatment -0.0184 0.239 0.88 0.0025 0.259 0.96 1.3024 0.9991 SpOx1.1_004281 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C14 compound treatment -0.0054 0.252 0.93 0.0185 0.275 1.02 1.3783 0.999 SpOx1.1_004282 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C15 compound treatment -0.0094 0.248 0.92 6.0E-4 0.257 0.95 1.3208 0.9998 SpOx1.1_004283 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C16 compound treatment -0.0054 0.252 0.93 0.0025 0.259 0.96 1.3364 0.9999 SpOx1.1_004284 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C17 compound treatment 6.0E-4 0.258 0.95 0.0135 0.27 1.0 1.3808 0.9997 SpOx1.1_004285 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C18 compound treatment -0.0074 0.25 0.92 0.0025 0.259 0.96 1.331 0.9998 SpOx1.1_004286 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C19 compound treatment -0.0034 0.254 0.94 0.0105 0.267 0.99 1.3626 0.9997 SpOx1.1_004287 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C20 compound treatment -0.0134 0.244 0.9 -5.0E-4 0.256 0.95 1.3075 0.9997 SpOx1.1_004288 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C21 compound treatment -0.0034 0.254 0.94 0.0205 0.277 1.03 1.3888 0.999 SpOx1.1_004289 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C22 compound treatment -0.0114 0.246 0.91 -0.0024 0.254 0.94 1.3076 0.9998 SpOx1.1_004290 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C23 mock treatment -0.0104 0.247 0.91 -0.0115 0.245 0.91 1.2866 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 C24 mock treatment -0.5091 -0.252 -0.93 -0.5059 -0.25 -0.92 -1.3128 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D01 compound treatment -0.0134 0.244 0.9 -0.0074 0.249 0.92 1.2894 0.9999 SpOx1.1_004291 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D02 compound treatment -0.0144 0.243 0.9 -0.0094 0.247 0.91 1.2815 1.0 SpOx1.1_004292 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D03 compound treatment -0.0154 0.242 0.89 6.0E-4 0.257 0.95 1.305 0.9995 SpOx1.1_004293 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D04 compound treatment -0.0294 0.228 0.84 0.0085 0.265 0.98 1.2893 0.9971 SpOx1.1_004294 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D05 compound treatment -0.0134 0.244 0.9 0.0046 0.261 0.97 1.3207 0.9994 SpOx1.1_004295 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D06 compound treatment -0.0094 0.248 0.92 -0.0114 0.245 0.91 1.2894 1.0 SpOx1.1_004296 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D07 compound treatment -0.0054 0.252 0.93 0.0025 0.259 0.96 1.3364 0.9999 SpOx1.1_004297 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D08 compound treatment -0.0314 0.226 0.83 -0.0095 0.247 0.91 1.2369 0.999 SpOx1.1_004298 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D09 compound treatment 0.0016 0.259 0.96 -0.0104 0.246 0.91 1.3207 0.9997 SpOx1.1_004299 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D10 compound treatment -0.0174 0.24 0.89 -0.0024 0.254 0.94 1.292 0.9996 SpOx1.1_004300 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D11 compound treatment 0.0166 0.274 1.01 0.0165 0.273 1.01 1.4305 1.0 SpOx1.1_004301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D12 compound treatment -0.0144 0.243 0.9 0.0025 0.259 0.96 1.3128 0.9994 SpOx1.1_004302 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D13 compound treatment -0.0054 0.252 0.93 -0.0014 0.255 0.94 1.326 1.0 SpOx1.1_004303 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D14 compound treatment -0.0074 0.25 0.92 0.0295 0.286 1.06 1.4018 0.9977 SpOx1.1_004304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D15 compound treatment -0.0184 0.239 0.88 -0.0034 0.253 0.94 1.2867 0.9996 SpOx1.1_004305 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D16 compound treatment -0.0244 0.233 0.86 -0.0065 0.25 0.93 1.2631 0.9993 SpOx1.1_004306 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D17 compound treatment -0.0244 0.233 0.86 0.0025 0.259 0.96 1.2867 0.9985 SpOx1.1_004307 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D18 compound treatment -0.0124 0.245 0.9 -0.0015 0.255 0.94 1.3076 0.9998 SpOx1.1_004308 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D19 compound treatment -0.0224 0.235 0.87 -0.0075 0.249 0.92 1.2657 0.9995 SpOx1.1_004309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D20 compound treatment -4.0E-4 0.257 0.95 -0.0065 0.25 0.93 1.3259 0.9999 SpOx1.1_004310 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D21 compound treatment -0.0234 0.234 0.86 0.0055 0.262 0.97 1.297 0.9983 SpOx1.1_004311 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D22 compound treatment -0.0024 0.255 0.94 -0.0024 0.254 0.94 1.3313 1.0 SpOx1.1_004312 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D23 mock treatment -0.0074 0.25 0.92 0.0115 0.268 0.99 1.3547 0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 D24 mock treatment -0.5081 -0.251 -0.93 -0.5079 -0.252 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E01 compound treatment -0.0104 0.247 0.91 0.0085 0.265 0.98 1.3391 0.9993 SpOx1.1_004313 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E02 compound treatment -4.0E-4 0.257 0.95 0.0056 0.262 0.97 1.3574 0.9999 SpOx1.1_004314 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E03 compound treatment -0.0014 0.256 0.95 0.0046 0.261 0.97 1.3522 0.9999 SpOx1.1_004315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E04 compound treatment 0.0026 0.26 0.96 -4.0E-4 0.256 0.95 1.3496 1.0 SpOx1.1_004316 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E05 compound treatment 0.0086 0.266 0.98 0.0185 0.275 1.02 1.4148 0.9998 SpOx1.1_004317 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E06 compound treatment 0.0106 0.268 0.99 0.0115 0.268 0.99 1.4018 1.0 SpOx1.1_004318 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E07 compound treatment 0.0076 0.265 0.98 0.0135 0.27 1.0 1.3991 0.9999 SpOx1.1_004319 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E08 compound treatment 0.0156 0.273 1.01 0.0125 0.269 1.0 1.4174 1.0 SpOx1.1_004320 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E09 compound treatment 0.0076 0.265 0.98 5.0E-4 0.257 0.95 1.365 0.9999 SpOx1.1_004321 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E10 compound treatment 0.0196 0.277 1.02 0.0235 0.28 1.04 1.4567 1.0 SpOx1.1_004322 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E11 compound treatment -0.0154 0.242 0.89 0.0195 0.276 1.02 1.3546 0.9978 SpOx1.1_004323 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E12 compound treatment 0.0046 0.262 0.97 5.0E-4 0.257 0.95 1.3573 1.0 SpOx1.1_004324 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E13 compound treatment 0.0066 0.264 0.98 -0.0395 0.217 0.8 1.2576 0.9954 SpOx1.1_004325 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E14 compound treatment 6.0E-4 0.258 0.95 0.0135 0.27 1.0 1.3809 0.9997 SpOx1.1_004326 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E15 compound treatment 0.0136 0.271 1.0 0.0015 0.258 0.96 1.3833 0.9997 SpOx1.1_004327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E16 compound treatment 0.0036 0.261 0.96 0.0125 0.269 1.0 1.3861 0.9999 SpOx1.1_004328 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E17 compound treatment -0.0084 0.249 0.92 0.0235 0.28 1.04 1.3835 0.9982 SpOx1.1_004329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E18 compound treatment 0.0046 0.262 0.97 0.0165 0.273 1.01 1.3991 0.9998 SpOx1.1_004330 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E19 compound treatment 6.0E-4 0.258 0.95 0.0135 0.27 1.0 1.3808 0.9997 SpOx1.1_004331 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E20 compound treatment -0.0034 0.254 0.94 0.0125 0.269 1.0 1.3677 0.9995 SpOx1.1_004332 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E21 compound treatment 0.0056 0.263 0.97 0.0145 0.271 1.0 1.3965 0.9999 SpOx1.1_004333 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E22 compound treatment 0.0106 0.268 0.99 0.0095 0.266 0.99 1.3965 1.0 SpOx1.1_004334 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E23 mock treatment 0.0076 0.265 0.98 0.0115 0.268 0.99 1.394 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 E24 mock treatment -0.5081 -0.251 -0.93 -0.507 -0.251 -0.93 -1.3131 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F01 compound treatment -0.0204 0.237 0.88 -0.0104 0.246 0.91 1.2631 0.9998 SpOx1.1_004335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F02 compound treatment -0.0114 0.246 0.91 -0.0125 0.244 0.9 1.2814 1.0 SpOx1.1_004336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F03 compound treatment -0.0054 0.252 0.93 0.0036 0.26 0.96 1.3391 0.9999 SpOx1.1_004337 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F04 compound treatment -0.0124 0.245 0.9 0.0115 0.268 0.99 1.3416 0.9989 SpOx1.1_004338 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F05 compound treatment 0.0146 0.272 1.0 -0.0045 0.252 0.93 1.3703 0.9993 SpOx1.1_004339 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F06 compound treatment 0.0026 0.26 0.96 -5.0E-4 0.256 0.95 1.3493 1.0 SpOx1.1_004340 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F07 compound treatment -0.0044 0.253 0.93 -0.0215 0.235 0.87 1.2761 0.9994 SpOx1.1_004341 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F08 compound treatment 0.0056 0.263 0.97 0.0065 0.263 0.97 1.3755 1.0 SpOx1.1_004342 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F09 compound treatment -0.0194 0.238 0.88 0.0115 0.268 0.99 1.3233 0.9982 SpOx1.1_004343 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F10 compound treatment 0.0166 0.274 1.01 0.0095 0.266 0.99 1.4122 0.9999 SpOx1.1_004344 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F11 compound treatment -0.0124 0.245 0.9 0.0045 0.261 0.97 1.3234 0.9995 SpOx1.1_004345 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F12 compound treatment -0.0074 0.25 0.92 -0.0054 0.251 0.93 1.3103 1.0 SpOx1.1_004346 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F13 compound treatment 0.0056 0.263 0.97 0.0175 0.274 1.01 1.4044 0.9998 SpOx1.1_004347 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F14 compound treatment -0.0024 0.255 0.94 0.0125 0.269 1.0 1.3703 0.9996 SpOx1.1_004348 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F15 compound treatment 0.0076 0.265 0.98 0.0325 0.289 1.07 1.4489 0.999 SpOx1.1_004349 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F16 compound treatment 0.0146 0.272 1.0 0.0245 0.281 1.04 1.4462 0.9998 SpOx1.1_004350 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F17 compound treatment -0.0044 0.253 0.93 0.0015 0.258 0.96 1.3363 0.9999 SpOx1.1_004351 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F18 compound treatment 0.0096 0.267 0.99 0.0335 0.29 1.07 1.4567 0.9991 SpOx1.1_004352 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F19 compound treatment 0.0096 0.267 0.99 0.0065 0.263 0.97 1.3861 1.0 SpOx1.1_004353 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F20 compound treatment -4.0E-4 0.257 0.95 0.0045 0.261 0.97 1.3546 1.0 SpOx1.1_004354 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F21 compound treatment 0.0066 0.264 0.97 0.0195 0.276 1.02 1.4122 0.9997 SpOx1.1_004355 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F22 compound treatment 0.0046 0.262 0.97 0.0175 0.274 1.01 1.4018 0.9997 SpOx1.1_004356 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F23 mock treatment 0.0116 0.269 0.99 -0.0054 0.251 0.93 1.3599 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 F24 mock treatment -0.5091 -0.252 -0.93 -0.508 -0.252 -0.93 -1.3183 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G01 compound treatment -0.0034 0.254 0.94 -0.0105 0.246 0.91 1.3076 0.9999 SpOx1.1_004357 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G02 compound treatment -0.0104 0.247 0.91 -0.0034 0.253 0.94 1.3077 0.9999 SpOx1.1_004358 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G03 compound treatment -0.0184 0.239 0.88 -0.0024 0.254 0.94 1.2893 0.9995 SpOx1.1_004359 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G04 compound treatment 0.0126 0.27 1.0 0.0055 0.262 0.97 1.3913 0.9999 SpOx1.1_004360 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G05 compound treatment -0.0244 0.233 0.86 -0.0085 0.248 0.92 1.2579 0.9995 SpOx1.1_004361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G06 compound treatment -0.0164 0.241 0.89 -0.0034 0.253 0.94 1.292 0.9997 SpOx1.1_004362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G07 compound treatment 0.0066 0.264 0.98 0.0105 0.267 0.99 1.3886 1.0 SpOx1.1_004363 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G08 compound treatment 6.0E-4 0.258 0.95 -0.0054 0.251 0.93 1.3312 0.9999 SpOx1.1_004364 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G09 compound treatment -0.0054 0.252 0.93 0.0025 0.259 0.96 1.3365 0.9999 SpOx1.1_004365 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G10 compound treatment -0.0104 0.247 0.91 0.0105 0.267 0.99 1.3443 0.9992 SpOx1.1_004366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G11 compound treatment 6.0E-4 0.258 0.95 -0.0074 0.249 0.92 1.326 0.9999 2142233 SpOx1.1_004367 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCn9nnc%10ccccc9%10)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G12 compound treatment -0.0024 0.255 0.94 0.0135 0.27 1.0 1.373 0.9996 SpOx1.1_004368 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G13 compound treatment 0.0076 0.265 0.98 -5.0E-4 0.256 0.95 1.3624 0.9999 SpOx1.1_004369 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G14 compound treatment -0.0104 0.247 0.91 -4.0E-4 0.256 0.95 1.3156 0.9998 SpOx1.1_004370 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G15 compound treatment -0.0154 0.242 0.89 0.0085 0.265 0.98 1.3258 0.9989 SpOx1.1_004371 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G16 compound treatment 0.0126 0.27 1.0 -0.0144 0.242 0.9 1.339 0.9986 SpOx1.1_004372 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G17 compound treatment -0.0084 0.249 0.92 -0.0025 0.254 0.94 1.3153 0.9999 SpOx1.1_004373 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G18 compound treatment -0.0054 0.252 0.93 -0.0054 0.251 0.93 1.3155 1.0 SpOx1.1_004374 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G19 compound treatment 0.0026 0.26 0.96 -0.0095 0.247 0.91 1.3257 0.9997 SpOx1.1_004375 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G20 compound treatment -0.0304 0.227 0.84 -0.0055 0.251 0.93 1.2499 0.9987 SpOx1.1_004376 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G21 compound treatment -0.0094 0.248 0.92 -0.0135 0.243 0.9 1.284 1.0 SpOx1.1_004377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G22 compound treatment -0.0134 0.244 0.9 -0.0024 0.254 0.94 1.3025 0.9998 SpOx1.1_004378 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G23 mock treatment -0.0094 0.248 0.92 -0.0034 0.253 0.94 1.3103 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 G24 mock treatment -0.5081 -0.251 -0.93 -0.5079 -0.252 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H01 compound treatment -0.0104 0.247 0.91 -0.0114 0.245 0.91 1.2868 1.0 SpOx1.1_004379 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H02 compound treatment -0.0284 0.229 0.85 0.0105 0.267 0.99 1.2972 0.997 SpOx1.1_004380 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H03 compound treatment -0.0074 0.25 0.92 -0.0055 0.251 0.93 1.3102 1.0 SpOx1.1_004381 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H04 compound treatment -0.0124 0.245 0.9 -0.0034 0.253 0.94 1.3024 0.9998 SpOx1.1_004382 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H05 compound treatment -0.0144 0.243 0.9 -0.0125 0.244 0.9 1.2735 1.0 SpOx1.1_004383 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H06 compound treatment -0.0044 0.253 0.93 -0.0115 0.245 0.91 1.3024 0.9999 SpOx1.1_004384 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H07 compound treatment 6.0E-4 0.258 0.95 0.0125 0.269 1.0 1.3783 0.9998 SpOx1.1_004385 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H08 compound treatment -0.0134 0.244 0.9 -0.0064 0.25 0.93 1.292 0.9999 SpOx1.1_004386 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H09 compound treatment -0.0094 0.248 0.92 -0.0094 0.247 0.91 1.2946 1.0 SpOx1.1_004387 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H10 compound treatment -0.0094 0.248 0.92 0.0185 0.275 1.02 1.3678 0.9986 SpOx1.1_004388 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H11 compound treatment -0.0114 0.246 0.91 6.0E-4 0.257 0.95 1.3155 0.9997 SpOx1.1_004389 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H12 compound treatment -0.0064 0.251 0.93 -0.0124 0.244 0.9 1.2946 0.9999 SpOx1.1_004390 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H13 compound treatment 0.0016 0.259 0.96 -0.0175 0.239 0.89 1.3023 0.9992 SpOx1.1_004391 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H14 compound treatment -0.0014 0.256 0.95 -4.0E-4 0.256 0.95 1.3391 1.0 SpOx1.1_004392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H15 compound treatment -0.0044 0.253 0.93 0.0055 0.262 0.97 1.3469 0.9998 SpOx1.1_004393 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H16 compound treatment -4.0E-4 0.257 0.95 -0.0025 0.254 0.94 1.3363 1.0 SpOx1.1_004394 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H17 compound treatment 6.0E-4 0.258 0.95 -0.0115 0.245 0.91 1.3154 0.9997 SpOx1.1_004395 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H18 compound treatment -0.0174 0.24 0.89 -0.0175 0.239 0.89 1.2527 1.0 SpOx1.1_004396 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H19 compound treatment -0.0074 0.25 0.92 -0.0065 0.25 0.93 1.3076 1.0 SpOx1.1_004397 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H20 compound treatment -0.0064 0.251 0.93 -0.0035 0.253 0.94 1.3179 1.0 SpOx1.1_004398 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H21 compound treatment -0.0154 0.242 0.89 -0.0085 0.248 0.92 1.2815 0.9999 SpOx1.1_004399 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H22 compound treatment -0.0074 0.25 0.92 0.0025 0.259 0.96 1.3311 0.9998 SpOx1.1_004400 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H23 mock treatment -0.0144 0.243 0.9 0.0125 0.269 1.0 1.339 0.9986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 H24 mock treatment -0.5081 -0.251 -0.93 -0.5079 -0.252 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I01 compound treatment 0.0016 0.259 0.96 -0.0054 0.251 0.93 1.3338 0.9999 SpOx1.1_004401 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I02 compound treatment -0.0184 0.239 0.88 -0.0034 0.253 0.94 1.2867 0.9996 SpOx1.1_004402 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I03 compound treatment 0.0066 0.264 0.97 0.0085 0.265 0.98 1.3834 1.0 SpOx1.1_004403 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I04 compound treatment -0.0234 0.234 0.86 -0.0195 0.237 0.88 1.2316 1.0 SpOx1.1_004404 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I05 compound treatment -0.0184 0.239 0.88 0.0065 0.263 0.97 1.3128 0.9988 SpOx1.1_004405 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I06 compound treatment -0.0184 0.239 0.88 -0.0085 0.248 0.92 1.2736 0.9998 SpOx1.1_004406 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I07 compound treatment -0.0084 0.249 0.92 0.0045 0.261 0.97 1.3337 0.9997 SpOx1.1_004407 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I08 compound treatment -0.0104 0.247 0.91 -0.0134 0.243 0.9 1.2815 1.0 SpOx1.1_004408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I09 compound treatment -0.0074 0.25 0.92 -0.0114 0.245 0.91 1.2945 1.0 SpOx1.1_004409 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I10 compound treatment -0.0014 0.256 0.95 0.0115 0.268 0.99 1.3704 0.9997 SpOx1.1_004410 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I11 compound treatment -0.0064 0.251 0.93 0.0105 0.267 0.99 1.3548 0.9995 SpOx1.1_004411 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I12 compound treatment -0.0114 0.246 0.91 -0.0044 0.252 0.93 1.3025 0.9999 SpOx1.1_004412 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I13 compound treatment 0.0036 0.261 0.96 0.0025 0.259 0.96 1.3599 1.0 SpOx1.1_004413 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I14 compound treatment -0.0074 0.25 0.92 -0.0044 0.252 0.93 1.3129 1.0 SpOx1.1_004414 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I15 compound treatment -0.0164 0.241 0.89 -4.0E-4 0.256 0.95 1.2998 0.9995 SpOx1.1_004415 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I16 compound treatment -0.0274 0.23 0.85 -0.0075 0.249 0.92 1.2526 0.9992 SpOx1.1_004416 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I17 compound treatment 0.0066 0.264 0.98 -0.0055 0.251 0.93 1.3468 0.9997 SpOx1.1_004417 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I18 compound treatment -0.0014 0.256 0.95 -0.0295 0.227 0.84 1.2629 0.9983 SpOx1.1_004418 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I19 compound treatment -0.0244 0.233 0.86 0.0025 0.259 0.96 1.2867 0.9985 SpOx1.1_004419 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I20 compound treatment -0.0034 0.254 0.94 -0.0125 0.244 0.9 1.3022 0.9998 SpOx1.1_004420 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I21 compound treatment -0.0224 0.235 0.87 -0.0405 0.216 0.8 1.1792 0.9992 SpOx1.1_004421 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I22 compound treatment -0.0084 0.249 0.92 0.0035 0.26 0.96 1.3312 0.9997 SpOx1.1_004422 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I23 mock treatment 0.0076 0.265 0.98 0.0046 0.261 0.97 1.3757 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 I24 mock treatment -0.5091 -0.252 -0.93 -0.5079 -0.252 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J01 compound treatment -0.0164 0.241 0.89 -0.0165 0.24 0.89 1.2578 1.0 SpOx1.1_004423 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J02 compound treatment -0.0354 0.222 0.82 -0.0125 0.244 0.9 1.2186 0.9988 SpOx1.1_004424 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J03 compound treatment -0.0214 0.236 0.87 -0.0395 0.217 0.8 1.1845 0.9992 SpOx1.1_004425 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J04 compound treatment -0.0074 0.25 0.92 -0.0074 0.249 0.92 1.3051 1.0 SpOx1.1_004426 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J05 compound treatment -0.0154 0.242 0.89 -0.0105 0.246 0.91 1.2761 1.0 SpOx1.1_004427 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J06 compound treatment -0.0204 0.237 0.88 -0.0105 0.246 0.91 1.2631 0.9998 SpOx1.1_004428 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J07 compound treatment -0.0324 0.225 0.83 -0.0435 0.213 0.79 1.1453 0.9997 SpOx1.1_004429 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J08 compound treatment -0.0044 0.253 0.93 -0.0135 0.243 0.9 1.297 0.9998 SpOx1.1_004430 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J09 compound treatment -0.0134 0.244 0.9 -0.0125 0.244 0.9 1.2761 1.0 SpOx1.1_004431 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J10 compound treatment -0.0274 0.23 0.85 -0.0024 0.254 0.94 1.2658 0.9987 SpOx1.1_004432 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J11 compound treatment -0.0054 0.252 0.93 6.0E-4 0.257 0.95 1.3313 0.9999 SpOx1.1_004433 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J12 compound treatment -0.0124 0.245 0.9 -0.0014 0.255 0.94 1.3078 0.9998 SpOx1.1_004434 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J13 compound treatment -0.0354 0.222 0.82 -0.0084 0.248 0.92 1.2292 0.9984 SpOx1.1_004435 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J14 compound treatment -0.0164 0.241 0.89 -0.0054 0.251 0.93 1.2867 0.9998 SpOx1.1_004436 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J15 compound treatment -0.0064 0.251 0.93 -0.0084 0.248 0.92 1.3051 1.0 SpOx1.1_004437 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J16 compound treatment -0.0314 0.226 0.83 -0.0225 0.234 0.87 1.2029 0.9998 SpOx1.1_004438 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J17 compound treatment -0.0024 0.255 0.94 -0.0215 0.235 0.87 1.2814 0.9992 SpOx1.1_004439 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J18 compound treatment -0.0144 0.243 0.9 0.0025 0.259 0.96 1.3129 0.9994 SpOx1.1_004440 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J19 compound treatment -0.0084 0.249 0.92 -0.0185 0.238 0.88 1.2736 0.9998 SpOx1.1_004441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J20 compound treatment -0.0034 0.254 0.94 -0.0124 0.244 0.9 1.3025 0.9998 SpOx1.1_004442 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J21 compound treatment -0.0714 0.186 0.69 -0.0575 0.199 0.74 1.0065 0.9994 SpOx1.1_004443 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J22 compound treatment -0.0064 0.251 0.93 -0.0235 0.233 0.86 1.2657 0.9994 SpOx1.1_004444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J23 mock treatment -0.0114 0.246 0.91 -0.0175 0.239 0.89 1.2683 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 J24 mock treatment -0.5091 -0.252 -0.93 -0.5079 -0.252 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K01 compound treatment 0.0036 0.261 0.96 -0.0014 0.255 0.94 1.3495 0.9999 SpOx1.1_004445 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K02 compound treatment -0.0164 0.241 0.89 -0.0165 0.24 0.89 1.2578 1.0 SpOx1.1_004446 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K03 compound treatment -0.0024 0.255 0.94 -0.0044 0.252 0.93 1.326 1.0 SpOx1.1_004447 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K04 compound treatment -0.0044 0.253 0.93 -0.0095 0.247 0.91 1.3076 0.9999 SpOx1.1_004448 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K05 compound treatment -0.0204 0.237 0.88 -0.0115 0.245 0.91 1.2604 0.9998 SpOx1.1_004449 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K06 compound treatment -4.0E-4 0.257 0.95 -0.0105 0.246 0.91 1.3154 0.9998 SpOx1.1_004450 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K07 compound treatment -0.0534 0.204 0.75 -0.0135 0.243 0.9 1.1688 0.9961 SpOx1.1_004451 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K08 compound treatment -0.0194 0.238 0.88 -0.0035 0.253 0.94 1.284 0.9995 SpOx1.1_004452 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K09 compound treatment -0.0154 0.242 0.89 6.0E-4 0.257 0.95 1.305 0.9995 SpOx1.1_004453 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K10 compound treatment -0.0094 0.248 0.92 -0.0025 0.254 0.94 1.3128 0.9999 SpOx1.1_004454 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K11 compound treatment -0.0064 0.251 0.93 -0.0034 0.253 0.94 1.3182 1.0 SpOx1.1_004455 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K12 compound treatment -0.0174 0.24 0.89 -0.0044 0.252 0.93 1.2868 0.9997 SpOx1.1_004456 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K13 compound treatment -0.0314 0.226 0.83 -0.0064 0.25 0.93 1.2449 0.9987 SpOx1.1_004457 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K14 compound treatment -0.0034 0.254 0.94 -0.0035 0.253 0.94 1.3259 1.0 SpOx1.1_004458 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K15 compound treatment 0.0026 0.26 0.96 0.0045 0.261 0.97 1.3626 1.0 SpOx1.1_004459 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K16 compound treatment -0.0034 0.254 0.94 0.0035 0.26 0.96 1.3442 0.9999 SpOx1.1_004460 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K17 compound treatment -0.0254 0.232 0.86 -0.0124 0.244 0.9 1.2448 0.9996 SpOx1.1_004461 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K18 compound treatment -0.0104 0.247 0.91 -0.0215 0.235 0.87 1.2604 0.9997 SpOx1.1_004462 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K19 compound treatment -0.0224 0.235 0.87 -0.0325 0.224 0.83 1.2002 0.9997 SpOx1.1_004463 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K20 compound treatment -0.0154 0.242 0.89 -0.0045 0.252 0.93 1.2919 0.9998 SpOx1.1_004464 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K21 compound treatment -0.0154 0.242 0.89 -0.0175 0.239 0.89 1.2579 1.0 SpOx1.1_004465 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K22 compound treatment -0.0054 0.252 0.93 0.0015 0.258 0.96 1.3337 0.9999 SpOx1.1_004466 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K23 mock treatment -0.0054 0.252 0.93 -0.0034 0.253 0.94 1.3207 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 K24 mock treatment -0.5081 -0.251 -0.93 -0.5079 -0.252 -0.93 -1.3154 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L01 compound treatment -0.0124 0.245 0.9 -0.0025 0.254 0.94 1.3049 0.9998 SpOx1.1_004467 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L02 compound treatment 6.0E-4 0.258 0.95 0.0075 0.264 0.98 1.3652 0.9999 SpOx1.1_004468 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L03 compound treatment -0.0024 0.255 0.94 0.0185 0.275 1.02 1.3862 0.9992 SpOx1.1_004469 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L04 compound treatment -0.0014 0.256 0.95 -0.0055 0.251 0.93 1.3258 1.0 SpOx1.1_004470 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L05 compound treatment -0.0074 0.25 0.92 0.0055 0.262 0.97 1.339 0.9997 SpOx1.1_004471 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L06 compound treatment 0.0116 0.269 0.99 -0.0065 0.25 0.93 1.3571 0.9994 SpOx1.1_004472 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L07 compound treatment -0.0104 0.247 0.91 -0.0105 0.246 0.91 1.2893 1.0 SpOx1.1_004473 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L08 compound treatment 6.0E-4 0.258 0.95 -0.0084 0.248 0.92 1.3234 0.9998 SpOx1.1_004474 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L09 compound treatment 0.0116 0.269 0.99 0.0085 0.265 0.98 1.3964 1.0 SpOx1.1_004475 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L10 compound treatment -0.0144 0.243 0.9 0.0175 0.274 1.01 1.352 0.9981 SpOx1.1_004476 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L11 compound treatment -0.0034 0.254 0.94 0.0075 0.264 0.98 1.3547 0.9998 SpOx1.1_004477 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L12 compound treatment -0.0184 0.239 0.88 0.0015 0.258 0.96 1.2997 0.9992 2143533 SpOx1.1_004478 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCn%10nnc%11ccccc%10%11)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L13 compound treatment -0.0034 0.254 0.94 0.0085 0.265 0.98 1.3572 0.9997 SpOx1.1_004479 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L14 compound treatment -0.0074 0.25 0.92 0.0045 0.261 0.97 1.3363 0.9997 SpOx1.1_004480 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L15 compound treatment 0.0056 0.263 0.97 0.0055 0.262 0.97 1.373 1.0 SpOx1.1_004481 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L16 compound treatment 6.0E-4 0.258 0.95 6.0E-4 0.257 0.95 1.347 1.0 SpOx1.1_004482 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L17 compound treatment -0.0044 0.253 0.93 0.0025 0.259 0.96 1.3389 0.9999 SpOx1.1_004483 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L18 compound treatment 0.0096 0.267 0.99 0.0035 0.26 0.96 1.3781 0.9999 SpOx1.1_004484 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L19 compound treatment 0.0056 0.263 0.97 0.0055 0.262 0.97 1.3729 1.0 SpOx1.1_004485 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L20 compound treatment 0.0086 0.266 0.98 5.0E-4 0.257 0.95 1.3676 0.9999 SpOx1.1_004486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L21 compound treatment -0.0124 0.245 0.9 0.0035 0.26 0.96 1.3207 0.9995 SpOx1.1_004487 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L22 compound treatment 0.0026 0.26 0.96 0.0075 0.264 0.98 1.3703 1.0 SpOx1.1_004488 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L23 mock treatment 0.0136 0.271 1.0 0.0155 0.272 1.01 1.4201 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 L24 mock treatment -0.509 -0.252 -0.93 -0.509 -0.253 -0.94 -1.3207 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M01 compound treatment 0.0076 0.265 0.98 0.0115 0.268 0.99 1.3938 1.0 SpOx1.1_004489 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M02 compound treatment 0.0096 0.267 0.99 -0.0014 0.255 0.94 1.3652 0.9998 SpOx1.1_004490 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M03 compound treatment 0.0056 0.263 0.97 0.0345 0.291 1.08 1.449 0.9987 SpOx1.1_004491 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M04 compound treatment 0.0126 0.27 1.0 0.0065 0.263 0.97 1.3938 0.9999 SpOx1.1_004492 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M05 compound treatment 0.0056 0.263 0.97 0.0025 0.259 0.96 1.365 1.0 SpOx1.1_004493 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M06 compound treatment 0.0086 0.266 0.98 0.0135 0.27 1.0 1.4017 1.0 SpOx1.1_004494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M07 compound treatment 0.0036 0.261 0.96 0.0105 0.267 0.99 1.3808 0.9999 SpOx1.1_004495 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M08 compound treatment -0.0134 0.244 0.9 -0.0135 0.243 0.9 1.2734 1.0 SpOx1.1_004496 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M09 compound treatment -0.0044 0.253 0.93 0.0065 0.263 0.97 1.3496 0.9998 SpOx1.1_004497 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M10 compound treatment -0.0114 0.246 0.91 -0.0114 0.245 0.91 1.2842 1.0 SpOx1.1_004498 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M11 compound treatment 0.0086 0.266 0.98 -0.0035 0.253 0.94 1.3572 0.9997 SpOx1.1_004499 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M12 compound treatment -0.0074 0.25 0.92 -0.0115 0.245 0.91 1.2944 1.0 SpOx1.1_004500 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M13 compound treatment -0.0014 0.256 0.95 -0.0014 0.255 0.94 1.3365 1.0 SpOx1.1_004501 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M14 compound treatment 0.0066 0.264 0.98 0.0175 0.274 1.01 1.407 0.9998 SpOx1.1_004502 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M15 compound treatment -0.0094 0.248 0.92 -0.0115 0.245 0.91 1.2893 1.0 SpOx1.1_004503 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M16 compound treatment -0.0074 0.25 0.92 -0.0265 0.23 0.85 1.2552 0.9992 SpOx1.1_004504 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M17 compound treatment -0.0084 0.249 0.92 -5.0E-4 0.256 0.95 1.3206 0.9999 SpOx1.1_004505 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M18 compound treatment 0.0036 0.261 0.96 0.0095 0.266 0.99 1.3781 0.9999 SpOx1.1_004506 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M19 compound treatment 0.0156 0.273 1.01 0.0125 0.269 1.0 1.4174 1.0 SpOx1.1_004507 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M20 compound treatment -0.0124 0.245 0.9 -5.0E-4 0.256 0.95 1.3102 0.9997 SpOx1.1_004508 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M21 compound treatment 0.0016 0.259 0.96 0.0025 0.259 0.96 1.3546 1.0 SpOx1.1_004509 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M22 compound treatment -0.0064 0.251 0.93 -0.0015 0.255 0.94 1.3232 1.0 SpOx1.1_004510 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M23 mock treatment 0.0106 0.268 0.99 -0.0014 0.255 0.94 1.3678 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 M24 mock treatment -0.5091 -0.252 -0.93 -0.5079 -0.252 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N01 compound treatment -0.0314 0.226 0.83 -0.0035 0.253 0.94 1.2526 0.9983 SpOx1.1_004511 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N02 compound treatment -0.0204 0.237 0.88 -0.0125 0.244 0.9 1.2578 0.9999 SpOx1.1_004512 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N03 compound treatment 6.0E-4 0.258 0.95 -0.0155 0.241 0.89 1.3049 0.9995 SpOx1.1_004513 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N04 compound treatment -0.0134 0.244 0.9 -0.0135 0.243 0.9 1.2736 1.0 SpOx1.1_004514 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N05 compound treatment -0.0024 0.255 0.94 6.0E-4 0.257 0.95 1.3391 1.0 SpOx1.1_004515 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N06 compound treatment -0.0234 0.234 0.86 -0.0065 0.25 0.93 1.2657 0.9994 SpOx1.1_004516 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N07 compound treatment -0.0294 0.228 0.84 -0.0075 0.249 0.92 1.2473 0.999 SpOx1.1_004517 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N08 compound treatment -0.0334 0.224 0.83 -0.0025 0.254 0.94 1.2499 0.9979 SpOx1.1_004518 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N09 compound treatment -0.0434 0.214 0.79 -0.0215 0.235 0.87 1.1741 0.9988 SpOx1.1_004519 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N10 compound treatment -0.0294 0.228 0.84 -0.0195 0.237 0.88 1.216 0.9998 SpOx1.1_004520 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N11 compound treatment -0.0254 0.232 0.86 -0.0175 0.239 0.89 1.2317 0.9999 SpOx1.1_004521 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N12 compound treatment -0.0114 0.246 0.91 -0.0015 0.255 0.94 1.3101 0.9998 SpOx1.1_004522 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N13 compound treatment -0.0074 0.25 0.92 -0.0104 0.246 0.91 1.2972 1.0 SpOx1.1_004523 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N14 compound treatment -0.0144 0.243 0.9 -0.0095 0.247 0.91 1.2814 1.0 SpOx1.1_004524 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N15 compound treatment -0.0294 0.228 0.84 0.0055 0.262 0.97 1.2815 0.9975 SpOx1.1_004525 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N16 compound treatment -0.0274 0.23 0.85 -0.0285 0.228 0.84 1.1977 1.0 SpOx1.1_004526 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N17 compound treatment -0.0214 0.236 0.87 -0.0245 0.232 0.86 1.2239 1.0 SpOx1.1_004527 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N18 compound treatment -0.0164 0.241 0.89 -0.0155 0.241 0.89 1.2603 1.0 SpOx1.1_004528 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N19 compound treatment -0.0204 0.237 0.88 -0.0185 0.238 0.88 1.2422 1.0 SpOx1.1_004529 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N20 compound treatment -0.0174 0.24 0.89 -0.0075 0.249 0.92 1.2787 0.9998 SpOx1.1_004530 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N21 compound treatment 0.0066 0.264 0.98 -0.0015 0.255 0.94 1.3572 0.9999 SpOx1.1_004531 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N22 compound treatment -0.0074 0.25 0.92 -0.0025 0.254 0.94 1.3179 1.0 SpOx1.1_004532 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N23 mock treatment 0.0036 0.261 0.96 -0.0054 0.251 0.93 1.3391 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 N24 mock treatment -0.5091 -0.252 -0.93 -0.5079 -0.252 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O01 compound treatment -0.0134 0.244 0.9 0.0025 0.259 0.96 1.3154 0.9995 SpOx1.1_004533 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O02 compound treatment 0.0016 0.259 0.96 -4.0E-4 0.256 0.95 1.3469 1.0 SpOx1.1_004534 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O03 compound treatment 6.0E-4 0.258 0.95 -0.0135 0.243 0.9 1.3101 0.9996 SpOx1.1_004535 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O04 compound treatment -4.0E-4 0.257 0.95 0.0015 0.258 0.96 1.3467 1.0 SpOx1.1_004536 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O05 compound treatment 0.0036 0.261 0.96 -0.0025 0.254 0.94 1.3467 0.9999 SpOx1.1_004537 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O06 compound treatment -0.0094 0.248 0.92 -0.0105 0.246 0.91 1.2918 1.0 SpOx1.1_004538 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O07 compound treatment -0.0094 0.248 0.92 0.0085 0.265 0.98 1.3415 0.9994 SpOx1.1_004539 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O08 compound treatment 0.0076 0.265 0.98 -0.0055 0.251 0.93 1.3494 0.9997 SpOx1.1_004540 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O09 compound treatment 0.0016 0.259 0.96 0.0015 0.258 0.96 1.352 1.0 SpOx1.1_004541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O10 compound treatment -0.0114 0.246 0.91 -0.0185 0.238 0.88 1.2657 0.9999 SpOx1.1_004542 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O11 compound treatment -0.0084 0.249 0.92 -0.0165 0.24 0.89 1.2786 0.9999 SpOx1.1_004543 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O12 compound treatment 6.0E-4 0.258 0.95 -0.0205 0.236 0.87 1.2918 0.9991 SpOx1.1_004544 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O13 compound treatment -0.0104 0.247 0.91 -0.0025 0.254 0.94 1.3102 0.9999 SpOx1.1_004545 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O14 compound treatment -0.0044 0.253 0.93 -5.0E-4 0.256 0.95 1.3311 1.0 SpOx1.1_004546 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O15 compound treatment 0.0136 0.271 1.0 -0.0015 0.255 0.94 1.3755 0.9996 SpOx1.1_004547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O16 compound treatment -0.0144 0.243 0.9 0.0045 0.261 0.97 1.318 0.9993 SpOx1.1_004548 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O17 compound treatment -0.0054 0.252 0.93 -0.0025 0.254 0.94 1.3232 1.0 SpOx1.1_004549 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O18 compound treatment -0.0014 0.256 0.95 -0.0135 0.243 0.9 1.3049 0.9997 SpOx1.1_004550 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O19 compound treatment -0.0044 0.253 0.93 -0.0015 0.255 0.94 1.3284 1.0 SpOx1.1_004551 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O20 compound treatment -0.0184 0.239 0.88 -0.0095 0.247 0.91 1.2709 0.9998 SpOx1.1_004552 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O21 compound treatment 0.0116 0.269 0.99 -0.0045 0.252 0.93 1.3624 0.9995 SpOx1.1_004553 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O22 compound treatment 0.0116 0.269 0.99 0.0065 0.263 0.97 1.3912 1.0 SpOx1.1_004554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O23 mock treatment 0.0166 0.274 1.01 -0.0074 0.249 0.92 1.3677 0.9989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 O24 mock treatment -0.5091 -0.252 -0.93 -0.5079 -0.252 -0.93 -1.318 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P01 compound treatment -0.0344 0.223 0.82 -0.0305 0.226 0.84 1.1741 1.0 SpOx1.1_004555 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P02 compound treatment -0.0134 0.244 0.9 -0.0154 0.241 0.89 1.2683 1.0 SpOx1.1_004556 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P03 compound treatment -0.0264 0.231 0.85 -0.0084 0.248 0.92 1.2527 0.9993 SpOx1.1_004557 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P04 compound treatment -0.0224 0.235 0.87 -0.0295 0.227 0.84 1.208 0.9999 SpOx1.1_004558 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P05 compound treatment -0.0174 0.24 0.89 -0.0415 0.215 0.8 1.1896 0.9986 SpOx1.1_004559 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P06 compound treatment -0.0124 0.245 0.9 -0.0225 0.234 0.87 1.2526 0.9998 SpOx1.1_004560 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P07 compound treatment -0.0384 0.219 0.81 -0.0195 0.237 0.88 1.1924 0.9992 SpOx1.1_004561 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P08 compound treatment -0.0264 0.231 0.85 -0.0114 0.245 0.91 1.2448 0.9995 SpOx1.1_004562 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P09 compound treatment -0.0194 0.238 0.88 -0.0325 0.224 0.83 1.208 0.9996 SpOx1.1_004563 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P10 compound treatment -0.0264 0.231 0.85 -0.0275 0.229 0.85 1.2028 1.0 SpOx1.1_004564 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P11 compound treatment -0.0384 0.219 0.81 -0.0445 0.212 0.79 1.1269 0.9999 SpOx1.1_004565 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P12 compound treatment -0.0344 0.223 0.82 -0.0194 0.237 0.88 1.203 0.9995 SpOx1.1_004566 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P13 compound treatment -0.0234 0.234 0.86 -0.0395 0.217 0.8 1.1792 0.9993 SpOx1.1_004567 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P14 compound treatment -0.0114 0.246 0.91 -0.0275 0.229 0.85 1.2421 0.9994 SpOx1.1_004568 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P15 compound treatment -0.0334 0.224 0.83 -0.0175 0.239 0.89 1.2107 0.9994 SpOx1.1_004569 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P16 compound treatment -0.0274 0.23 0.85 -0.0305 0.226 0.84 1.1923 1.0 SpOx1.1_004570 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P17 compound treatment -0.0234 0.234 0.86 -0.0395 0.217 0.8 1.1792 0.9993 SpOx1.1_004571 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P18 compound treatment -0.0454 0.212 0.78 -0.0175 0.239 0.89 1.1794 0.9981 SpOx1.1_004572 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P19 compound treatment -0.0234 0.234 0.86 -0.0215 0.235 0.87 1.2264 1.0 SpOx1.1_004573 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P20 compound treatment -0.0284 0.229 0.85 -0.0175 0.239 0.89 1.2238 0.9997 SpOx1.1_004574 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P21 compound treatment -0.0344 0.223 0.82 -0.0205 0.236 0.87 1.2003 0.9996 SpOx1.1_004575 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P22 compound treatment -0.0284 0.229 0.85 -0.5019 -0.246 -0.91 -0.0454 -0.0366 SpOx1.1_004576 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P23 mock treatment -0.0334 0.224 0.83 -0.0114 0.245 0.91 1.2265 0.9989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1290 P24 mock treatment -0.5091 -0.252 -0.93 -0.5109 -0.255 -0.94 -1.3259 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A01 compound treatment -0.0751 0.178 0.66 -0.0869 0.167 0.62 0.9025 0.9996 SpOx1.1_004577 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A02 compound treatment -0.055 0.198 0.73 -0.08 0.174 0.64 0.973 0.998 SpOx1.1_004578 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A03 compound treatment -0.0933 0.16 0.59 -0.077 0.177 0.66 0.8808 0.9986 SpOx1.1_004579 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A04 compound treatment -0.0863 0.167 0.62 -0.0849 0.169 0.63 0.8784 1.0 SpOx1.1_004580 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A05 compound treatment -0.074 0.179 0.66 -0.081 0.173 0.64 0.9207 0.9999 SpOx1.1_004581 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A06 compound treatment -0.084 0.169 0.62 -0.0859 0.168 0.62 0.8818 1.0 SpOx1.1_004582 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A07 compound treatment -0.0962 0.157 0.58 -0.064 0.19 0.7 0.9072 0.9953 SpOx1.1_004583 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A08 compound treatment -0.0761 0.177 0.65 -0.076 0.178 0.66 0.9284 1.0 SpOx1.1_004584 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A09 compound treatment -0.064 0.189 0.7 -0.0859 0.168 0.62 0.9339 0.9984 SpOx1.1_004585 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A10 compound treatment -0.0721 0.181 0.67 -0.08 0.174 0.64 0.9285 0.9998 SpOx1.1_004586 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A11 compound treatment -0.068 0.185 0.68 -0.076 0.178 0.66 0.9494 0.9998 SpOx1.1_004587 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A12 compound treatment -0.0621 0.191 0.71 -0.073 0.181 0.67 0.973 0.9997 SpOx1.1_004588 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A13 compound treatment -0.074 0.179 0.66 -0.082 0.172 0.64 0.9181 0.9998 SpOx1.1_004589 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A14 compound treatment -0.0701 0.183 0.68 -0.0839 0.17 0.63 0.9233 0.9994 SpOx1.1_004590 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A15 compound treatment -0.0761 0.177 0.65 -0.084 0.17 0.63 0.9075 0.9998 SpOx1.1_004591 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A16 compound treatment -0.063 0.19 0.7 -0.079 0.175 0.65 0.9546 0.9992 SpOx1.1_004592 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A17 compound treatment -0.0841 0.169 0.62 -0.077 0.177 0.66 0.9049 0.9997 SpOx1.1_004593 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A18 compound treatment -0.0721 0.181 0.67 -0.08 0.174 0.64 0.9283 0.9998 SpOx1.1_004594 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A19 compound treatment -0.0771 0.176 0.65 -0.0849 0.169 0.63 0.9024 0.9998 SpOx1.1_004595 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A20 compound treatment -0.0811 0.172 0.63 -0.079 0.175 0.65 0.9074 0.9999 SpOx1.1_004596 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A21 compound treatment -0.0611 0.192 0.71 -0.0829 0.171 0.63 0.9496 0.9984 SpOx1.1_004597 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A22 compound treatment -0.0721 0.181 0.67 -0.0869 0.167 0.62 0.9102 0.9993 SpOx1.1_004598 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A23 mock treatment -0.0701 0.183 0.68 -0.076 0.178 0.66 0.9442 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 A24 mock treatment -0.5018 -0.249 -0.92 -0.5041 -0.25 -0.93 -1.3064 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B01 compound treatment -0.005 0.248 0.92 -0.0089 0.245 0.91 1.2898 1.0 SpOx1.1_004599 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B02 compound treatment -0.007 0.246 0.91 -9.0E-4 0.253 0.94 1.3055 0.9999 2142913 SpOx1.1_004600 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B03 compound treatment 0.012 0.265 0.98 0.011 0.265 0.98 1.3866 1.0 SpOx1.1_004601 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B04 compound treatment -0.0121 0.241 0.89 0.015 0.269 1.0 1.3343 0.9984 SpOx1.1_004602 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B05 compound treatment 0.005 0.258 0.95 0.013 0.267 0.99 1.3735 0.9998 SpOx1.1_004603 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B06 compound treatment -0.0021 0.251 0.93 -0.006 0.248 0.92 1.3055 1.0 SpOx1.1_004604 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B07 compound treatment -0.006 0.247 0.91 0.005 0.259 0.96 1.3239 0.9997 SpOx1.1_004605 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B08 compound treatment 0.0149 0.268 0.99 0.014 0.268 0.99 1.4021 1.0 SpOx1.1_004606 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B09 compound treatment 0.014 0.267 0.99 1.0E-4 0.254 0.94 1.3631 0.9997 SpOx1.1_004607 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B10 compound treatment 0.013 0.266 0.98 0.004 0.258 0.96 1.3709 0.9999 SpOx1.1_004608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B11 compound treatment 0.004 0.257 0.95 -0.0019 0.252 0.93 1.3317 1.0 SpOx1.1_004609 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B12 compound treatment 0.0089 0.262 0.97 -0.0029 0.251 0.93 1.342 0.9998 SpOx1.1_004610 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B13 compound treatment 0.0139 0.267 0.99 0.001 0.255 0.94 1.3655 0.9998 SpOx1.1_004611 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B14 compound treatment 0.0029 0.256 0.95 0.016 0.27 1.0 1.3761 0.9996 SpOx1.1_004612 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B15 compound treatment -0.004 0.249 0.92 0.006 0.26 0.96 1.3316 0.9997 SpOx1.1_004613 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B16 compound treatment -0.001 0.252 0.93 0.0021 0.256 0.95 1.3291 1.0 SpOx1.1_004614 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B17 compound treatment 0.013 0.266 0.98 0.013 0.267 0.99 1.3944 1.0 SpOx1.1_004615 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B18 compound treatment 0.008 0.261 0.96 0.012 0.266 0.99 1.3787 0.9999 SpOx1.1_004616 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B19 compound treatment 0.0069 0.26 0.96 0.001 0.255 0.94 1.3472 1.0 SpOx1.1_004617 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B20 compound treatment 0.01 0.263 0.97 0.0021 0.256 0.95 1.3578 0.9999 SpOx1.1_004618 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B21 compound treatment 0.0159 0.269 0.99 0.007 0.261 0.97 1.3864 0.9999 SpOx1.1_004619 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B22 compound treatment -0.007 0.246 0.91 -0.005 0.249 0.92 1.2951 1.0 SpOx1.1_004620 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B23 mock treatment -0.0021 0.251 0.93 0.018 0.272 1.01 1.3683 0.9991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 B24 mock treatment -0.5008 -0.248 -0.92 -0.5011 -0.247 -0.92 -1.2959 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C01 compound treatment -0.0121 0.241 0.89 -0.01 0.244 0.9 1.2688 1.0 SpOx1.1_004621 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C02 compound treatment -0.017 0.236 0.87 -0.0019 0.252 0.93 1.2768 0.9994 SpOx1.1_004622 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C03 compound treatment -0.015 0.238 0.88 -0.015 0.239 0.89 1.2479 1.0 SpOx1.1_004623 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C04 compound treatment -0.02 0.233 0.86 1.0E-4 0.254 0.94 1.2742 0.999 SpOx1.1_004624 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C05 compound treatment -0.02 0.233 0.86 0.009 0.263 0.97 1.2977 0.9981 SpOx1.1_004625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C06 compound treatment -0.0021 0.251 0.93 -0.017 0.237 0.88 1.2766 0.9996 SpOx1.1_004626 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C07 compound treatment -0.0091 0.244 0.9 0.004 0.258 0.96 1.3131 0.9996 SpOx1.1_004627 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C08 compound treatment 0.0049 0.258 0.95 -0.0049 0.249 0.92 1.3263 0.9999 SpOx1.1_004628 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C09 compound treatment -0.0171 0.236 0.87 -0.023 0.231 0.86 1.2216 1.0 SpOx1.1_004629 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C10 compound treatment 0.007 0.26 0.96 -0.016 0.238 0.88 1.3029 0.9991 SpOx1.1_004630 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C11 compound treatment -0.0021 0.251 0.93 0.003 0.257 0.95 1.3289 0.9999 SpOx1.1_004631 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C12 compound treatment -0.0081 0.245 0.9 -0.009 0.245 0.91 1.2818 1.0 SpOx1.1_004632 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C13 compound treatment 0.001 0.254 0.94 -0.015 0.239 0.89 1.2898 0.9996 SpOx1.1_004633 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C14 compound treatment -0.0181 0.235 0.87 -0.015 0.239 0.89 1.2399 0.9999 SpOx1.1_004634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C15 compound treatment -0.0041 0.249 0.92 -0.015 0.239 0.89 1.2765 0.9998 SpOx1.1_004635 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C16 compound treatment 0.0019 0.255 0.94 0.002 0.256 0.95 1.3367 1.0 SpOx1.1_004636 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C17 compound treatment 0.0079 0.261 0.96 -0.005 0.249 0.92 1.334 0.9998 SpOx1.1_004637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C18 compound treatment 9.0E-4 0.254 0.94 0.002 0.256 0.95 1.334 1.0 SpOx1.1_004638 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C19 compound treatment 0.003 0.256 0.95 -0.011 0.243 0.9 1.3056 0.9997 SpOx1.1_004639 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C20 compound treatment 0.0 0.253 0.93 -0.013 0.241 0.89 1.2924 0.9997 SpOx1.1_004640 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C21 compound treatment 0.012 0.265 0.98 -0.015 0.239 0.89 1.3185 0.9987 SpOx1.1_004641 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C22 compound treatment -0.0091 0.244 0.9 -0.011 0.243 0.9 1.274 1.0 SpOx1.1_004642 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C23 mock treatment -0.024 0.229 0.85 -0.017 0.237 0.88 1.2191 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 C24 mock treatment -0.4988 -0.246 -0.91 -0.5011 -0.247 -0.92 -1.2907 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D01 compound treatment -0.008 0.245 0.91 -0.0069 0.247 0.92 1.2872 1.0 SpOx1.1_004643 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D02 compound treatment -0.006 0.247 0.91 -0.011 0.243 0.9 1.2819 1.0 SpOx1.1_004644 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D03 compound treatment -0.0031 0.25 0.92 -0.014 0.24 0.89 1.2819 0.9998 SpOx1.1_004645 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D04 compound treatment 0.015 0.268 0.99 -0.024 0.23 0.85 1.3027 0.9972 SpOx1.1_004646 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D05 compound treatment 0.0029 0.256 0.95 -0.0079 0.246 0.91 1.3134 0.9998 SpOx1.1_004647 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D06 compound treatment -0.0111 0.242 0.89 -0.01 0.244 0.9 1.2715 1.0 SpOx1.1_004648 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D07 compound treatment -0.0211 0.232 0.86 -0.021 0.233 0.86 1.2163 1.0 SpOx1.1_004649 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D08 compound treatment -0.0011 0.252 0.93 -0.011 0.243 0.9 1.2948 0.9999 SpOx1.1_004650 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D09 compound treatment -0.0141 0.239 0.88 -0.011 0.243 0.9 1.261 1.0 SpOx1.1_004651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D10 compound treatment -0.0021 0.251 0.93 -0.045 0.209 0.77 1.2032 0.996 SpOx1.1_004652 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D11 compound treatment 0.0139 0.267 0.99 0.007 0.261 0.97 1.3812 1.0 SpOx1.1_004653 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D12 compound treatment -0.0021 0.251 0.93 -0.0119 0.242 0.9 1.2898 0.9999 SpOx1.1_004654 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D13 compound treatment -0.004 0.249 0.92 1.0E-4 0.254 0.94 1.316 0.9999 SpOx1.1_004655 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D14 compound treatment 0.0159 0.269 0.99 -0.009 0.245 0.91 1.3445 0.999 SpOx1.1_004656 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D15 compound treatment -0.0111 0.242 0.89 -0.02 0.234 0.87 1.2452 0.9999 SpOx1.1_004657 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D16 compound treatment 0.018 0.271 1.0 0.005 0.259 0.96 1.3866 0.9998 SpOx1.1_004658 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D17 compound treatment 0.004 0.257 0.95 -0.01 0.244 0.9 1.3107 0.9997 SpOx1.1_004659 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D18 compound treatment 0.0079 0.261 0.96 -0.005 0.249 0.92 1.3341 0.9998 SpOx1.1_004660 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D19 compound treatment -0.0041 0.249 0.92 -0.019 0.235 0.87 1.266 0.9996 SpOx1.1_004661 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D20 compound treatment -0.0111 0.242 0.89 -0.004 0.25 0.93 1.2872 0.9998 SpOx1.1_004662 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D21 compound treatment 0.012 0.265 0.98 -0.017 0.237 0.88 1.3132 0.9985 2143753 SpOx1.1_004663 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCN(C)Cc9ccccc9)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D22 compound treatment 0.006 0.259 0.96 0.008 0.262 0.97 1.363 1.0 SpOx1.1_004664 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D23 mock treatment 0.01 0.263 0.97 -0.01 0.244 0.9 1.3263 0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 D24 mock treatment -0.5008 -0.248 -0.92 -0.5011 -0.247 -0.92 -1.2959 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E01 compound treatment 0.0029 0.256 0.95 -0.0069 0.247 0.92 1.3158 0.9999 SpOx1.1_004665 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E02 compound treatment 0.0019 0.255 0.94 0.005 0.259 0.96 1.3447 1.0 SpOx1.1_004666 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E03 compound treatment 0.0019 0.255 0.94 1.0E-4 0.254 0.94 1.3317 1.0 SpOx1.1_004667 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E04 compound treatment -0.007 0.246 0.91 0.008 0.262 0.97 1.329 0.9995 SpOx1.1_004668 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E05 compound treatment 0.014 0.267 0.99 0.018 0.272 1.01 1.4101 0.9999 SpOx1.1_004669 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E06 compound treatment 0.016 0.269 0.99 0.018 0.272 1.01 1.4155 1.0 SpOx1.1_004670 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E07 compound treatment -0.002 0.251 0.93 -0.006 0.248 0.92 1.3055 1.0 SpOx1.1_004671 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E08 compound treatment 0.0029 0.256 0.95 0.009 0.263 0.97 1.3576 0.9999 SpOx1.1_004672 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E09 compound treatment 0.005 0.258 0.95 0.011 0.265 0.98 1.3683 0.9999 SpOx1.1_004673 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E10 compound treatment 0.0209 0.274 1.01 0.01 0.264 0.98 1.4073 0.9999 SpOx1.1_004674 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E11 compound treatment 0.0089 0.262 0.97 -0.021 0.233 0.86 1.2948 0.9984 SpOx1.1_004675 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E12 compound treatment 0.0029 0.256 0.95 0.0091 0.263 0.97 1.3578 0.9999 SpOx1.1_004676 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E13 compound treatment 0.012 0.265 0.98 0.008 0.262 0.97 1.3787 1.0 SpOx1.1_004677 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E14 compound treatment 0.0119 0.265 0.98 -0.0069 0.247 0.92 1.3394 0.9994 SpOx1.1_004678 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E15 compound treatment 0.0069 0.26 0.96 0.021 0.275 1.02 1.3995 0.9996 SpOx1.1_004679 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E16 compound treatment 0.0079 0.261 0.96 0.0 0.254 0.94 1.3471 0.9999 SpOx1.1_004680 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E17 compound treatment 0.0209 0.274 1.01 -0.0069 0.247 0.92 1.3629 0.9987 SpOx1.1_004681 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E18 compound treatment 0.021 0.274 1.01 0.007 0.261 0.97 1.3997 0.9997 SpOx1.1_004682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E19 compound treatment 0.0039 0.257 0.95 -0.0069 0.247 0.92 1.3185 0.9998 SpOx1.1_004683 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E20 compound treatment 0.0119 0.265 0.98 0.0 0.254 0.94 1.3576 0.9998 SpOx1.1_004684 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E21 compound treatment 0.0149 0.268 0.99 0.005 0.259 0.96 1.3785 0.9999 SpOx1.1_004685 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E22 compound treatment 0.0079 0.261 0.96 0.013 0.267 0.99 1.3812 0.9999 SpOx1.1_004686 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E23 mock treatment 0.0069 0.26 0.96 0.0041 0.258 0.96 1.3552 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 E24 mock treatment -0.4998 -0.247 -0.91 -0.5011 -0.247 -0.92 -1.2933 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F01 compound treatment -0.0111 0.242 0.89 -0.016 0.238 0.88 1.2557 1.0 SpOx1.1_004687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F02 compound treatment -0.015 0.238 0.88 -0.006 0.248 0.92 1.2715 0.9998 SpOx1.1_004688 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F03 compound treatment 0.0019 0.255 0.94 0.001 0.255 0.94 1.3342 1.0 SpOx1.1_004689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F04 compound treatment 0.01 0.263 0.97 -0.0089 0.245 0.91 1.329 0.9994 SpOx1.1_004690 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F05 compound treatment -0.0091 0.244 0.9 0.019 0.273 1.01 1.3525 0.9983 SpOx1.1_004691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F06 compound treatment 0.0089 0.262 0.97 0.004 0.258 0.96 1.3603 1.0 SpOx1.1_004692 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F07 compound treatment -0.0031 0.25 0.92 -0.004 0.25 0.93 1.308 1.0 SpOx1.1_004693 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F08 compound treatment 0.0149 0.268 0.99 0.01 0.264 0.98 1.3916 1.0 SpOx1.1_004694 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F09 compound treatment 0.0099 0.263 0.97 -0.019 0.235 0.87 1.3026 0.9985 SpOx1.1_004695 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F10 compound treatment 0.0119 0.265 0.98 0.017 0.271 1.0 1.4022 0.9999 SpOx1.1_004696 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F11 compound treatment 0.0079 0.261 0.96 -0.0069 0.247 0.92 1.3289 0.9997 SpOx1.1_004697 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F12 compound treatment -0.0041 0.249 0.92 0.004 0.258 0.96 1.3262 0.9998 SpOx1.1_004698 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F13 compound treatment 0.0019 0.255 0.94 0.008 0.262 0.97 1.3525 0.9999 SpOx1.1_004699 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F14 compound treatment 0.0199 0.273 1.01 0.0011 0.255 0.95 1.3813 0.9995 SpOx1.1_004700 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F15 compound treatment 0.0279 0.281 1.04 -0.0039 0.25 0.93 1.3891 0.9984 SpOx1.1_004701 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F16 compound treatment 0.0169 0.27 1.0 0.01 0.264 0.98 1.3968 1.0 SpOx1.1_004702 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F17 compound treatment 0.0059 0.259 0.96 1.0E-4 0.254 0.94 1.342 1.0 SpOx1.1_004703 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F18 compound treatment 0.0399 0.293 1.08 0.003 0.257 0.95 1.4387 0.998 SpOx1.1_004704 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F19 compound treatment 0.0099 0.263 0.97 0.005 0.259 0.96 1.3654 1.0 SpOx1.1_004705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F20 compound treatment 0.0119 0.265 0.98 0.01 0.264 0.98 1.3838 1.0 SpOx1.1_004706 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F21 compound treatment 0.0129 0.266 0.98 0.0011 0.255 0.95 1.363 0.9998 SpOx1.1_004707 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F22 compound treatment 0.0209 0.274 1.01 0.007 0.261 0.97 1.3995 0.9997 SpOx1.1_004708 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F23 mock treatment -0.008 0.245 0.91 0.015 0.269 1.0 1.3448 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 F24 mock treatment -0.501 -0.248 -0.92 -0.5021 -0.248 -0.92 -1.299 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G01 compound treatment -0.015 0.238 0.88 0.004 0.258 0.96 1.2977 0.9991 SpOx1.1_004709 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G02 compound treatment -0.0031 0.25 0.92 -0.008 0.246 0.91 1.2976 1.0 SpOx1.1_004710 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G03 compound treatment -0.02 0.233 0.86 -0.025 0.229 0.85 1.2086 1.0 SpOx1.1_004711 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G04 compound treatment -0.0111 0.242 0.89 -0.002 0.252 0.93 1.2923 0.9998 SpOx1.1_004712 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G05 compound treatment -0.0061 0.247 0.91 -0.015 0.239 0.89 1.2713 0.9999 SpOx1.1_004713 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G06 compound treatment -0.0021 0.251 0.93 -0.014 0.24 0.89 1.2845 0.9998 SpOx1.1_004714 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G07 compound treatment 0.0049 0.258 0.95 0.004 0.258 0.96 1.3497 1.0 SpOx1.1_004715 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G08 compound treatment -0.0081 0.245 0.9 -0.0069 0.247 0.92 1.2871 1.0 SpOx1.1_004716 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G09 compound treatment 0.0059 0.259 0.96 -0.0069 0.247 0.92 1.3237 0.9998 2143933 SpOx1.1_004717 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G10 compound treatment 0.0109 0.264 0.98 -0.0069 0.247 0.92 1.3368 0.9995 SpOx1.1_004718 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G11 compound treatment -0.017 0.236 0.87 -0.008 0.246 0.91 1.261 0.9998 SpOx1.1_004719 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G12 compound treatment 0.005 0.258 0.95 -0.0049 0.249 0.92 1.3264 0.9999 SpOx1.1_004720 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G13 compound treatment -0.0101 0.243 0.9 -0.0069 0.247 0.92 1.282 1.0 SpOx1.1_004721 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G14 compound treatment -0.0091 0.244 0.9 -0.01 0.244 0.9 1.2767 1.0 SpOx1.1_004722 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G15 compound treatment 0.004 0.257 0.95 -0.0069 0.247 0.92 1.3186 0.9998 SpOx1.1_004723 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G16 compound treatment -0.0191 0.234 0.86 -0.012 0.242 0.9 1.2453 0.9998 SpOx1.1_004724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G17 compound treatment -0.01 0.243 0.9 -0.054 0.2 0.74 1.1588 0.9955 SpOx1.1_004725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G18 compound treatment -0.0181 0.235 0.87 -0.024 0.23 0.85 1.2163 1.0 SpOx1.1_004726 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G19 compound treatment -0.0181 0.235 0.87 -0.0069 0.247 0.92 1.2609 0.9996 SpOx1.1_004727 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G20 compound treatment -0.013 0.24 0.89 -0.029 0.225 0.83 1.2165 0.9995 2144681 SpOx1.1_004728 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G21 compound treatment -0.0171 0.236 0.87 -0.015 0.239 0.89 1.2425 1.0 SpOx1.1_004729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G22 compound treatment -0.0041 0.249 0.92 -0.0129 0.241 0.89 1.2818 0.9999 SpOx1.1_004730 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G23 mock treatment -0.005 0.248 0.92 -0.012 0.242 0.9 1.2819 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 G24 mock treatment -0.5018 -0.249 -0.92 -0.5031 -0.249 -0.92 -1.3038 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H01 compound treatment -0.008 0.245 0.91 -0.0089 0.245 0.91 1.282 1.0 SpOx1.1_004731 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H02 compound treatment 0.014 0.267 0.99 -0.02 0.234 0.87 1.3106 0.9979 SpOx1.1_004732 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H03 compound treatment -0.0141 0.239 0.88 -0.011 0.243 0.9 1.261 1.0 SpOx1.1_004733 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H04 compound treatment -0.008 0.245 0.91 -0.0129 0.241 0.89 1.2716 1.0 SpOx1.1_004734 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H05 compound treatment -0.0041 0.249 0.92 -0.003 0.251 0.93 1.3079 1.0 SpOx1.1_004735 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H06 compound treatment -0.016 0.237 0.88 -0.017 0.237 0.88 1.2402 1.0 SpOx1.1_004736 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H07 compound treatment -0.018 0.235 0.87 -0.006 0.248 0.92 1.2638 0.9996 SpOx1.1_004737 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H08 compound treatment -0.0021 0.251 0.93 -0.028 0.226 0.84 1.2477 0.9987 SpOx1.1_004738 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H09 compound treatment -0.0081 0.245 0.9 -0.0039 0.25 0.93 1.295 0.9999 SpOx1.1_004739 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H10 compound treatment 0.0239 0.277 1.02 -0.0049 0.249 0.92 1.376 0.9987 SpOx1.1_004740 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H11 compound treatment -0.005 0.248 0.92 -0.021 0.233 0.86 1.2583 0.9996 SpOx1.1_004741 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H12 compound treatment 0.0019 0.255 0.94 -0.008 0.246 0.91 1.3107 0.9999 SpOx1.1_004742 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H13 compound treatment -0.0111 0.242 0.89 -0.0029 0.251 0.93 1.2899 0.9998 SpOx1.1_004743 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H14 compound treatment 0.0069 0.26 0.96 -0.008 0.246 0.91 1.3237 0.9997 SpOx1.1_004744 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H15 compound treatment 0.0029 0.256 0.95 -0.01 0.244 0.9 1.308 0.9998 SpOx1.1_004745 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H16 compound treatment -1.0E-4 0.253 0.93 -0.0059 0.248 0.92 1.3106 1.0 SpOx1.1_004746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H17 compound treatment -0.0021 0.251 0.93 0.004 0.258 0.96 1.3315 0.9999 SpOx1.1_004747 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H18 compound treatment -0.0071 0.246 0.91 -0.018 0.236 0.87 1.2608 0.9998 SpOx1.1_004748 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H19 compound treatment -0.0101 0.243 0.9 -0.022 0.232 0.86 1.2425 0.9998 SpOx1.1_004749 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H20 compound treatment -0.0141 0.239 0.88 -0.017 0.237 0.88 1.2451 1.0 SpOx1.1_004750 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H21 compound treatment -0.0081 0.245 0.9 -0.014 0.24 0.89 1.2687 1.0 SpOx1.1_004751 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H22 compound treatment -0.003 0.25 0.92 -0.006 0.248 0.92 1.3029 1.0 SpOx1.1_004752 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H23 mock treatment 0.013 0.266 0.98 -0.01 0.244 0.9 1.3342 0.9991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 H24 mock treatment -0.5008 -0.248 -0.92 -0.5021 -0.248 -0.92 -1.2985 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I01 compound treatment -0.0091 0.244 0.9 -0.003 0.251 0.93 1.2949 0.9999 SpOx1.1_004753 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I02 compound treatment -0.0101 0.243 0.9 -0.014 0.24 0.89 1.2635 1.0 SpOx1.1_004754 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I03 compound treatment -0.0071 0.246 0.91 0.001 0.255 0.94 1.3106 0.9998 SpOx1.1_004755 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I04 compound treatment -0.0201 0.233 0.86 -0.014 0.24 0.89 1.2373 0.9999 SpOx1.1_004756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I05 compound treatment 9.0E-4 0.254 0.94 -0.012 0.242 0.9 1.2975 0.9997 SpOx1.1_004757 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I06 compound treatment -0.0131 0.24 0.89 -0.02 0.234 0.87 1.2399 0.9999 SpOx1.1_004758 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I07 compound treatment -0.0181 0.235 0.87 -0.039 0.215 0.8 1.1769 0.9991 SpOx1.1_004759 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I08 compound treatment -0.0211 0.232 0.86 -0.02 0.234 0.87 1.2189 1.0 SpOx1.1_004760 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I09 compound treatment -0.0061 0.247 0.91 0.008 0.262 0.97 1.3315 0.9995 SpOx1.1_004761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I10 compound treatment 0.006 0.259 0.96 0.0021 0.256 0.95 1.3474 1.0 SpOx1.1_004762 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I11 compound treatment 0.0089 0.262 0.97 -0.014 0.24 0.89 1.3132 0.9991 SpOx1.1_004763 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I12 compound treatment -0.0031 0.25 0.92 -0.004 0.25 0.93 1.308 1.0 SpOx1.1_004764 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I13 compound treatment -0.0101 0.243 0.9 0.001 0.255 0.94 1.3027 0.9997 SpOx1.1_004765 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I14 compound treatment -0.0021 0.251 0.93 -0.012 0.242 0.9 1.2898 0.9999 SpOx1.1_004766 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I15 compound treatment -0.004 0.249 0.92 -0.021 0.233 0.86 1.2609 0.9995 SpOx1.1_004767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I16 compound treatment -0.007 0.246 0.91 -0.025 0.229 0.85 1.2426 0.9994 SpOx1.1_004768 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I17 compound treatment -0.0131 0.24 0.89 0.005 0.259 0.96 1.3054 0.9992 SpOx1.1_004769 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I18 compound treatment -0.0181 0.235 0.87 -0.0049 0.249 0.92 1.2663 0.9995 SpOx1.1_004770 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I19 compound treatment 0.0069 0.26 0.96 -0.019 0.235 0.87 1.2948 0.9988 SpOx1.1_004771 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I20 compound treatment -1.0E-4 0.253 0.93 -0.002 0.252 0.93 1.321 1.0 SpOx1.1_004772 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I21 compound treatment -0.0181 0.235 0.87 -0.006 0.248 0.92 1.2634 0.9996 SpOx1.1_004773 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I22 compound treatment 0.0029 0.256 0.95 -0.018 0.236 0.87 1.2869 0.9992 SpOx1.1_004774 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I23 mock treatment 0.001 0.254 0.94 0.0031 0.257 0.95 1.3369 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 I24 mock treatment -0.5008 -0.248 -0.92 -0.5031 -0.249 -0.92 -1.3011 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J01 compound treatment -0.017 0.236 0.87 -0.011 0.243 0.9 1.2532 0.9999 SpOx1.1_004775 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J02 compound treatment -0.008 0.245 0.91 -0.036 0.218 0.81 1.2111 0.9984 SpOx1.1_004776 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J03 compound treatment -0.029 0.224 0.83 -0.014 0.24 0.89 1.2139 0.9994 SpOx1.1_004777 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J04 compound treatment -0.0081 0.245 0.9 -0.0029 0.251 0.93 1.2975 0.9999 SpOx1.1_004778 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J05 compound treatment -0.0131 0.24 0.89 -0.027 0.227 0.84 1.2215 0.9997 SpOx1.1_004779 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J06 compound treatment 9.0E-4 0.254 0.94 -0.016 0.238 0.88 1.2869 0.9995 SpOx1.1_004780 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J07 compound treatment -0.019 0.234 0.86 -0.019 0.235 0.87 1.2271 1.0 SpOx1.1_004781 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J08 compound treatment -0.0091 0.244 0.9 -0.035 0.219 0.81 1.2111 0.9986 SpOx1.1_004782 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J09 compound treatment -0.001 0.252 0.93 -0.012 0.242 0.9 1.2923 0.9998 SpOx1.1_004783 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J10 compound treatment -0.0101 0.243 0.9 -0.0169 0.237 0.88 1.2558 0.9999 SpOx1.1_004784 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J11 compound treatment 0.0089 0.262 0.97 -0.015 0.239 0.89 1.3106 0.999 SpOx1.1_004785 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J12 compound treatment 9.0E-4 0.254 0.94 -0.011 0.243 0.9 1.3001 0.9998 SpOx1.1_004786 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J13 compound treatment -0.007 0.246 0.91 -0.039 0.215 0.8 1.2059 0.9978 SpOx1.1_004787 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J14 compound treatment -0.001 0.252 0.93 -0.019 0.235 0.87 1.274 0.9994 SpOx1.1_004788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J15 compound treatment -0.015 0.238 0.88 -0.0089 0.245 0.91 1.2637 0.9999 SpOx1.1_004789 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J16 compound treatment -0.017 0.236 0.87 -0.014 0.24 0.89 1.2453 0.9999 SpOx1.1_004790 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J17 compound treatment -0.0131 0.24 0.89 -0.021 0.233 0.86 1.2374 0.9999 SpOx1.1_004791 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J18 compound treatment -1.0E-4 0.253 0.93 -0.026 0.228 0.84 1.2581 0.9987 SpOx1.1_004792 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J19 compound treatment -0.0251 0.228 0.84 -0.026 0.228 0.84 1.1928 1.0 SpOx1.1_004793 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J20 compound treatment -0.011 0.242 0.89 -0.05 0.204 0.76 1.1667 0.9965 SpOx1.1_004794 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J21 compound treatment -0.001 0.252 0.93 -0.008 0.246 0.91 1.3028 0.9999 SpOx1.1_004795 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J22 compound treatment -0.008 0.245 0.91 0.009 0.263 0.97 1.329 0.9993 SpOx1.1_004796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J23 mock treatment -0.0141 0.239 0.88 -0.01 0.244 0.9 1.2636 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 J24 mock treatment -0.5008 -0.248 -0.92 -0.5021 -0.248 -0.92 -1.2985 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K01 compound treatment -0.0111 0.242 0.89 0.006 0.26 0.96 1.3132 0.9993 SpOx1.1_004797 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K02 compound treatment -0.0261 0.227 0.84 -0.015 0.239 0.89 1.2191 0.9996 SpOx1.1_004798 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K03 compound treatment -0.024 0.229 0.85 -0.014 0.24 0.89 1.227 0.9997 SpOx1.1_004799 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K04 compound treatment -0.0121 0.241 0.89 -0.013 0.241 0.89 1.2608 1.0 SpOx1.1_004800 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K05 compound treatment -0.033 0.22 0.81 -0.04 0.214 0.79 1.1355 0.9999 SpOx1.1_004801 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K06 compound treatment -0.0021 0.251 0.93 0.0 0.254 0.94 1.321 1.0 SpOx1.1_004802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K07 compound treatment -0.006 0.247 0.91 -0.05 0.204 0.76 1.1798 0.9956 SpOx1.1_004803 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K08 compound treatment -1.0E-4 0.253 0.93 -0.021 0.233 0.86 1.2714 0.9992 SpOx1.1_004804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K09 compound treatment -0.004 0.249 0.92 -0.017 0.237 0.88 1.2714 0.9997 SpOx1.1_004805 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K10 compound treatment 0.006 0.259 0.96 -0.001 0.253 0.94 1.3394 0.9999 SpOx1.1_004806 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K11 compound treatment 9.0E-4 0.254 0.94 -0.0049 0.249 0.92 1.316 1.0 SpOx1.1_004807 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K12 compound treatment -0.0031 0.25 0.92 -0.0049 0.249 0.92 1.3054 1.0 SpOx1.1_004808 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K13 compound treatment -0.005 0.248 0.92 -0.039 0.215 0.8 1.2111 0.9976 SpOx1.1_004809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K14 compound treatment -0.0021 0.251 0.93 -0.0059 0.248 0.92 1.3054 1.0 SpOx1.1_004810 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K15 compound treatment -0.001 0.252 0.93 0.004 0.258 0.96 1.3343 0.9999 SpOx1.1_004811 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K16 compound treatment 0.0059 0.259 0.96 -0.0019 0.252 0.93 1.3368 0.9999 SpOx1.1_004812 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K17 compound treatment -0.006 0.247 0.91 -0.039 0.215 0.8 1.2085 0.9977 SpOx1.1_004813 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K18 compound treatment -0.0141 0.239 0.88 0.009 0.263 0.97 1.3133 0.9988 SpOx1.1_004814 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K19 compound treatment -0.0191 0.234 0.86 -0.019 0.235 0.87 1.2268 1.0 SpOx1.1_004815 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K20 compound treatment -0.0141 0.239 0.88 -0.03 0.224 0.83 1.2111 0.9995 SpOx1.1_004816 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K21 compound treatment -0.023 0.23 0.85 -0.019 0.235 0.87 1.2166 0.9999 SpOx1.1_004817 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K22 compound treatment 0.0049 0.258 0.95 0.001 0.255 0.94 1.3419 1.0 SpOx1.1_004818 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K23 mock treatment -0.006 0.247 0.91 -0.009 0.245 0.91 1.2871 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 K24 mock treatment -0.5008 -0.248 -0.92 -0.5021 -0.248 -0.92 -1.2985 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L01 compound treatment 0.0039 0.257 0.95 -0.014 0.24 0.89 1.3001 0.9995 SpOx1.1_004819 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L02 compound treatment 0.008 0.261 0.96 0.001 0.255 0.94 1.3501 0.9999 SpOx1.1_004820 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L03 compound treatment 0.0069 0.26 0.96 0.005 0.259 0.96 1.3577 1.0 SpOx1.1_004821 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L04 compound treatment 0.0029 0.256 0.95 0.002 0.256 0.95 1.3393 1.0 SpOx1.1_004822 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L05 compound treatment 0.0029 0.256 0.95 -0.006 0.248 0.92 1.3183 0.9999 SpOx1.1_004823 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L06 compound treatment -0.0071 0.246 0.91 0.003 0.257 0.95 1.3158 0.9997 SpOx1.1_004824 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L07 compound treatment -0.018 0.235 0.87 -0.022 0.232 0.86 1.2217 1.0 SpOx1.1_004825 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L08 compound treatment -0.024 0.229 0.85 -0.019 0.235 0.87 1.2139 0.9999 SpOx1.1_004826 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L09 compound treatment 0.0179 0.271 1.0 0.005 0.259 0.96 1.3864 0.9998 SpOx1.1_004827 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L10 compound treatment 0.0229 0.276 1.02 -0.017 0.237 0.88 1.3418 0.9972 SpOx1.1_004828 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L11 compound treatment 0.0169 0.27 1.0 -0.003 0.251 0.93 1.3628 0.9994 SpOx1.1_004829 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L12 compound treatment 0.0119 0.265 0.98 -0.001 0.253 0.94 1.355 0.9998 2142517 SpOx1.1_004830 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L13 compound treatment 0.0129 0.266 0.98 -0.003 0.251 0.93 1.3523 0.9996 SpOx1.1_004831 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L14 compound treatment 0.017 0.27 1.0 0.001 0.255 0.94 1.3735 0.9996 SpOx1.1_004832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L15 compound treatment 0.004 0.257 0.95 0.013 0.267 0.99 1.3709 0.9998 SpOx1.1_004833 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L16 compound treatment 0.0119 0.265 0.98 0.0 0.254 0.94 1.3576 0.9998 SpOx1.1_004834 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L17 compound treatment 0.0199 0.273 1.01 0.01 0.264 0.98 1.4047 0.9999 SpOx1.1_004835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L18 compound treatment 0.002 0.255 0.94 0.008 0.262 0.97 1.3526 0.9999 SpOx1.1_004836 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L19 compound treatment 0.004 0.257 0.95 -0.008 0.246 0.91 1.316 0.9998 SpOx1.1_004837 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L20 compound treatment -0.0011 0.252 0.93 0.004 0.258 0.96 1.3341 0.9999 SpOx1.1_004838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L21 compound treatment 0.0059 0.259 0.96 -0.015 0.239 0.89 1.3027 0.9993 SpOx1.1_004839 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L22 compound treatment 0.0169 0.27 1.0 0.009 0.263 0.97 1.3942 0.9999 SpOx1.1_004840 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L23 mock treatment 0.017 0.27 1.0 0.016 0.27 1.0 1.4127 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 L24 mock treatment -0.502 -0.249 -0.92 -0.503 -0.249 -0.92 -1.304 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M01 compound treatment 0.0099 0.263 0.97 0.011 0.265 0.98 1.3812 1.0 SpOx1.1_004841 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M02 compound treatment -0.0091 0.244 0.9 0.01 0.264 0.98 1.329 0.9992 SpOx1.1_004842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M03 compound treatment 0.0059 0.259 0.96 -0.0049 0.249 0.92 1.3289 0.9998 SpOx1.1_004843 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M04 compound treatment 0.001 0.254 0.94 0.008 0.262 0.97 1.35 0.9999 SpOx1.1_004844 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M05 compound treatment -0.0051 0.248 0.92 -0.005 0.249 0.92 1.3 1.0 SpOx1.1_004845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M06 compound treatment 0.0039 0.257 0.95 -0.006 0.248 0.92 1.3209 0.9999 SpOx1.1_004846 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M07 compound treatment 0.001 0.254 0.94 -0.005 0.249 0.92 1.316 1.0 SpOx1.1_004847 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M08 compound treatment -0.009 0.244 0.9 -0.006 0.248 0.92 1.2872 1.0 SpOx1.1_004848 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M09 compound treatment 0.0049 0.258 0.95 -0.012 0.242 0.9 1.3078 0.9995 SpOx1.1_004849 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M10 compound treatment -0.0091 0.244 0.9 -0.02 0.234 0.87 1.2505 0.9998 SpOx1.1_004850 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M11 compound treatment -0.001 0.252 0.93 0.003 0.257 0.95 1.3316 0.9999 SpOx1.1_004851 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M12 compound treatment -0.0031 0.25 0.92 -0.001 0.253 0.94 1.3158 1.0 SpOx1.1_004852 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M13 compound treatment 0.0029 0.256 0.95 -0.009 0.245 0.91 1.3105 0.9998 SpOx1.1_004853 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M14 compound treatment 0.0169 0.27 1.0 0.003 0.257 0.95 1.3785 0.9997 SpOx1.1_004854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M15 compound treatment -0.007 0.246 0.91 -0.006 0.248 0.92 1.2924 1.0 SpOx1.1_004855 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M16 compound treatment -0.0221 0.231 0.85 0.0011 0.255 0.95 1.2716 0.9987 SpOx1.1_004856 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M17 compound treatment 0.0199 0.273 1.01 -0.0059 0.248 0.92 1.3631 0.9989 SpOx1.1_004857 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M18 compound treatment 0.014 0.267 0.99 0.001 0.255 0.94 1.3657 0.9998 SpOx1.1_004858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M19 compound treatment 0.0029 0.256 0.95 0.0 0.254 0.94 1.334 1.0 SpOx1.1_004859 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M20 compound treatment 0.0119 0.265 0.98 0.0 0.254 0.94 1.3576 0.9998 SpOx1.1_004860 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M21 compound treatment -0.0031 0.25 0.92 -0.004 0.25 0.93 1.3079 1.0 SpOx1.1_004861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M22 compound treatment 0.005 0.258 0.95 0.001 0.255 0.94 1.3421 1.0 SpOx1.1_004862 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M23 mock treatment -0.0021 0.251 0.93 0.008 0.262 0.97 1.3421 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 M24 mock treatment -0.4998 -0.247 -0.91 -0.5031 -0.249 -0.92 -1.2985 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N01 compound treatment -0.0011 0.252 0.93 -0.017 0.237 0.88 1.2791 0.9996 SpOx1.1_004863 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N02 compound treatment -0.015 0.238 0.88 -0.023 0.231 0.86 1.2269 0.9999 SpOx1.1_004864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N03 compound treatment -0.0271 0.226 0.83 -0.005 0.249 0.92 1.2425 0.9987 SpOx1.1_004865 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N04 compound treatment -0.0071 0.246 0.91 -0.009 0.245 0.91 1.2844 1.0 SpOx1.1_004866 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N05 compound treatment -0.0021 0.251 0.93 -0.0129 0.241 0.89 1.2871 0.9998 SpOx1.1_004867 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N06 compound treatment -0.03 0.223 0.82 -0.048 0.206 0.76 1.1223 0.9993 SpOx1.1_004868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N07 compound treatment -0.0131 0.24 0.89 -0.037 0.217 0.8 1.1953 0.9988 SpOx1.1_004869 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N08 compound treatment 9.0E-4 0.254 0.94 -0.033 0.221 0.82 1.2423 0.9977 SpOx1.1_004870 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N09 compound treatment -0.0211 0.232 0.86 -0.044 0.21 0.78 1.1561 0.9988 SpOx1.1_004871 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N10 compound treatment 0.0079 0.261 0.96 -0.025 0.229 0.85 1.2816 0.998 SpOx1.1_004872 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N11 compound treatment -0.015 0.238 0.88 -0.015 0.239 0.89 1.2479 1.0 SpOx1.1_004873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N12 compound treatment 0.0049 0.258 0.95 -0.0069 0.247 0.92 1.3211 0.9998 SpOx1.1_004874 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N13 compound treatment 9.0E-4 0.254 0.94 -0.007 0.247 0.92 1.3106 0.9999 SpOx1.1_004875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N14 compound treatment -0.008 0.245 0.91 -0.005 0.249 0.92 1.2924 1.0 SpOx1.1_004876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N15 compound treatment 0.0199 0.273 1.01 -0.019 0.235 0.87 1.3288 0.9973 SpOx1.1_004877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N16 compound treatment -0.0021 0.251 0.93 0.002 0.256 0.95 1.3263 0.9999 SpOx1.1_004878 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N17 compound treatment -0.0091 0.244 0.9 -0.0149 0.239 0.89 1.2636 1.0 SpOx1.1_004879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N18 compound treatment -0.0091 0.244 0.9 -0.011 0.243 0.9 1.2738 1.0 SpOx1.1_004880 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N19 compound treatment -0.009 0.244 0.9 -0.017 0.237 0.88 1.2585 0.9999 SpOx1.1_004881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N20 compound treatment 0.0099 0.263 0.97 -0.01 0.244 0.9 1.3262 0.9994 SpOx1.1_004882 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N21 compound treatment -0.0071 0.246 0.91 -0.001 0.253 0.94 1.3053 0.9999 SpOx1.1_004883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N22 compound treatment -0.0071 0.246 0.91 -0.016 0.238 0.88 1.266 0.9999 SpOx1.1_004884 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N23 mock treatment 0.0029 0.256 0.95 0.004 0.258 0.96 1.3447 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 N24 mock treatment -0.4998 -0.247 -0.91 -0.5031 -0.249 -0.92 -1.2985 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O01 compound treatment 0.006 0.259 0.96 -0.0129 0.241 0.89 1.3081 0.9994 SpOx1.1_004885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O02 compound treatment -0.0071 0.246 0.91 0.004 0.258 0.96 1.3184 0.9997 SpOx1.1_004886 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O03 compound treatment -0.0131 0.24 0.89 -0.007 0.247 0.92 1.2739 0.9999 SpOx1.1_004887 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O04 compound treatment 0.0039 0.257 0.95 0.006 0.26 0.96 1.3524 1.0 SpOx1.1_004888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O05 compound treatment -0.014 0.239 0.88 -0.007 0.247 0.92 1.2715 0.9998 SpOx1.1_004889 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O06 compound treatment -0.007 0.246 0.91 -0.01 0.244 0.9 1.282 1.0 SpOx1.1_004890 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O07 compound treatment -0.0011 0.252 0.93 -0.049 0.205 0.76 1.1953 0.9949 SpOx1.1_004891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O08 compound treatment -0.0021 0.251 0.93 0.0 0.254 0.94 1.321 1.0 SpOx1.1_004892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O09 compound treatment -0.0101 0.243 0.9 -0.015 0.239 0.89 1.2607 1.0 SpOx1.1_004893 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O10 compound treatment -0.016 0.237 0.88 -0.011 0.243 0.9 1.2557 0.9999 SpOx1.1_004894 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O11 compound treatment -0.0051 0.248 0.92 -0.011 0.243 0.9 1.2843 1.0 SpOx1.1_004895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O12 compound treatment -0.0161 0.237 0.88 -0.003 0.251 0.93 1.2766 0.9995 SpOx1.1_004896 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O13 compound treatment 0.0059 0.259 0.96 -0.011 0.243 0.9 1.3131 0.9995 SpOx1.1_004897 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O14 compound treatment 0.0099 0.263 0.97 1.0E-4 0.254 0.94 1.3525 0.9999 SpOx1.1_004898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O15 compound treatment 0.0109 0.264 0.98 0.012 0.266 0.99 1.3864 1.0 SpOx1.1_004899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O16 compound treatment 0.0169 0.27 1.0 -0.0059 0.248 0.92 1.3551 0.9992 SpOx1.1_004900 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O17 compound treatment 0.012 0.265 0.98 0.0 0.254 0.94 1.3578 0.9998 SpOx1.1_004901 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O18 compound treatment -0.0141 0.239 0.88 0.0 0.254 0.94 1.2896 0.9995 SpOx1.1_004902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O19 compound treatment -0.0011 0.252 0.93 -0.009 0.245 0.91 1.3001 0.9999 SpOx1.1_004903 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O20 compound treatment -0.0041 0.249 0.92 -0.0159 0.238 0.88 1.274 0.9998 SpOx1.1_004904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O21 compound treatment 0.0039 0.257 0.95 0.006 0.26 0.96 1.3524 1.0 SpOx1.1_004905 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O22 compound treatment 0.0069 0.26 0.96 0.011 0.265 0.98 1.3733 0.9999 SpOx1.1_004906 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O23 mock treatment -0.001 0.252 0.93 0.017 0.271 1.0 1.3683 0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 O24 mock treatment -0.5008 -0.248 -0.92 -0.5031 -0.249 -0.92 -1.3011 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P01 compound treatment -0.0351 0.218 0.81 -0.03 0.224 0.83 1.1562 0.9999 SpOx1.1_004907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P02 compound treatment -0.0121 0.241 0.89 -0.0139 0.24 0.89 1.2583 1.0 SpOx1.1_004908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P03 compound treatment -0.0041 0.249 0.92 -0.024 0.23 0.85 1.2529 0.9993 SpOx1.1_004909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P04 compound treatment -0.028 0.225 0.83 -0.026 0.228 0.84 1.1852 1.0 SpOx1.1_004910 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P05 compound treatment -0.0251 0.228 0.84 -0.017 0.237 0.88 1.2164 0.9998 SpOx1.1_004911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P06 compound treatment -0.0251 0.228 0.84 -0.018 0.236 0.87 1.2137 0.9998 SpOx1.1_004912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P07 compound treatment -0.0191 0.234 0.86 -0.033 0.221 0.82 1.1901 0.9996 SpOx1.1_004913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P08 compound treatment -0.1488 0.104 0.38 -0.047 0.207 0.77 0.8143 0.9491 SpOx1.1_004914 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P09 compound treatment -0.0271 0.226 0.83 -0.025 0.229 0.85 1.1902 1.0 SpOx1.1_004915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P10 compound treatment -0.0261 0.227 0.84 -0.03 0.224 0.83 1.1798 1.0 SpOx1.1_004916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P11 compound treatment -0.034 0.219 0.81 -0.041 0.213 0.79 1.13 0.9999 SpOx1.1_004917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P12 compound treatment -0.0151 0.238 0.88 -0.029 0.225 0.83 1.2111 0.9997 SpOx1.1_004918 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P13 compound treatment -0.025 0.228 0.84 -0.023 0.231 0.86 1.2008 1.0 SpOx1.1_004919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P14 compound treatment -0.0121 0.241 0.89 -0.01 0.244 0.9 1.2687 1.0 SpOx1.1_004920 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P15 compound treatment -0.005 0.248 0.92 -0.023 0.231 0.86 1.253 0.9994 SpOx1.1_004921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P16 compound treatment -0.0191 0.234 0.86 -0.0129 0.241 0.89 1.2426 0.9999 SpOx1.1_004922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P17 compound treatment -0.024 0.229 0.85 -0.015 0.239 0.89 1.2244 0.9997 SpOx1.1_004923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P18 compound treatment -0.008 0.245 0.91 -0.031 0.223 0.83 1.2244 0.999 SpOx1.1_004924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P19 compound treatment -0.0071 0.246 0.91 -0.024 0.23 0.85 1.2451 0.9995 SpOx1.1_004925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P20 compound treatment -0.002 0.251 0.93 -0.011 0.243 0.9 1.2925 0.9999 SpOx1.1_004926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P21 compound treatment 9.0E-4 0.254 0.94 -0.02 0.234 0.87 1.2765 0.9992 SpOx1.1_004927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P22 compound treatment -0.005 0.248 0.92 -0.016 0.238 0.88 1.2714 0.9998 SpOx1.1_004928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P23 mock treatment 0.0019 0.255 0.94 -0.031 0.223 0.83 1.2504 0.9979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1291 P24 mock treatment -0.4998 -0.247 -0.91 -0.5021 -0.248 -0.92 -1.2959 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A01 compound treatment -0.0964 0.155 0.57 -0.086 0.166 0.61 0.8409 0.9994 SpOx1.1_004929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A02 compound treatment -0.0865 0.165 0.61 -0.0778 0.174 0.64 0.8883 0.9996 SpOx1.1_004930 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A03 compound treatment -0.0845 0.167 0.62 -0.0798 0.172 0.64 0.8883 0.9999 SpOx1.1_004931 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A04 compound treatment -0.0904 0.161 0.6 -0.082 0.17 0.63 0.867 0.9997 SpOx1.1_004932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A05 compound treatment -0.0785 0.173 0.64 -0.0778 0.174 0.64 0.9092 1.0 SpOx1.1_004933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A06 compound treatment -0.0825 0.169 0.63 -0.0828 0.169 0.63 0.8856 1.0 SpOx1.1_004934 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A07 compound treatment -0.0675 0.184 0.68 -0.0638 0.188 0.7 0.9747 0.9999 SpOx1.1_004935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A08 compound treatment -0.0815 0.17 0.63 -0.0738 0.178 0.66 0.9118 0.9997 SpOx1.1_004936 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A09 compound treatment -0.1024 0.149 0.55 -0.096 0.156 0.58 0.799 0.9998 SpOx1.1_004937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A10 compound treatment -0.0835 0.168 0.62 -0.0788 0.173 0.64 0.8935 0.9999 SpOx1.1_004938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A11 compound treatment -0.0795 0.172 0.64 -0.0748 0.177 0.66 0.9144 0.9999 SpOx1.1_004939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A12 compound treatment -0.0745 0.177 0.66 -0.0648 0.187 0.69 0.9537 0.9996 SpOx1.1_004940 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A13 compound treatment -0.0915 0.16 0.59 -0.0798 0.172 0.64 0.87 0.9993 SpOx1.1_004941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A14 compound treatment -0.0884 0.163 0.6 -0.084 0.168 0.62 0.867 0.9999 SpOx1.1_004942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A15 compound treatment -0.0815 0.17 0.63 -0.0698 0.182 0.67 0.9223 0.9994 SpOx1.1_004943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A16 compound treatment -0.0815 0.17 0.63 -0.0768 0.175 0.65 0.9039 0.9999 SpOx1.1_004944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A17 compound treatment -0.0755 0.176 0.65 -0.0728 0.179 0.66 0.9301 1.0 SpOx1.1_004945 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A18 compound treatment -0.0805 0.171 0.63 -0.0698 0.182 0.67 0.9249 0.9995 SpOx1.1_004946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A19 compound treatment -0.0815 0.17 0.63 -0.0768 0.175 0.65 0.9039 0.9999 SpOx1.1_004947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A20 compound treatment -0.0765 0.175 0.65 -0.0678 0.184 0.68 0.9406 0.9997 SpOx1.1_004948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A21 compound treatment -0.0944 0.157 0.58 -0.092 0.16 0.59 0.8304 1.0 SpOx1.1_004949 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A22 compound treatment -0.0864 0.165 0.61 -0.0838 0.168 0.62 0.8728 1.0 SpOx1.1_004950 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A23 mock treatment -0.0745 0.177 0.66 -0.0878 0.164 0.61 0.8934 0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 A24 mock treatment -0.4971 -0.245 -0.91 -0.4968 -0.245 -0.91 -1.2832 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B01 compound treatment -0.0205 0.231 0.86 -0.0118 0.24 0.89 1.2338 0.9998 SpOx1.1_004951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B02 compound treatment -0.0064 0.245 0.91 0.0022 0.254 0.94 1.3072 0.9998 2142173 SpOx1.1_004952 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCN(C)Cc%10ccccc%10)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B03 compound treatment 0.0045 0.256 0.95 0.0142 0.266 0.99 1.3672 0.9998 SpOx1.1_004953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B04 compound treatment 0.0135 0.265 0.98 0.0182 0.27 1.0 1.4012 1.0 SpOx1.1_004954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B05 compound treatment 0.0145 0.266 0.98 0.0192 0.271 1.0 1.4065 1.0 SpOx1.1_004955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B06 compound treatment 0.0016 0.253 0.94 0.0042 0.256 0.95 1.3333 1.0 SpOx1.1_004956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B07 compound treatment 5.0E-4 0.252 0.93 0.0062 0.258 0.96 1.3358 0.9999 SpOx1.1_004957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B08 compound treatment 0.0125 0.264 0.98 0.0192 0.271 1.0 1.4012 0.9999 SpOx1.1_004958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B09 compound treatment -5.0E-4 0.251 0.93 0.0112 0.263 0.97 1.3464 0.9997 SpOx1.1_004959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B10 compound treatment -0.0015 0.25 0.93 0.0052 0.257 0.95 1.328 0.9999 SpOx1.1_004960 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B11 compound treatment -5.0E-4 0.251 0.93 0.0062 0.258 0.96 1.3332 0.9999 SpOx1.1_004961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B12 compound treatment -0.0095 0.242 0.9 -0.0048 0.247 0.92 1.2809 0.9999 SpOx1.1_004962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B13 compound treatment -0.0085 0.243 0.9 0.0022 0.254 0.94 1.3019 0.9997 SpOx1.1_004963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B14 compound treatment 0.0065 0.258 0.96 0.0162 0.268 0.99 1.3778 0.9998 SpOx1.1_004964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B15 compound treatment -0.0034 0.248 0.92 0.0012 0.253 0.94 1.3124 0.9999 SpOx1.1_004965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B16 compound treatment -0.0015 0.25 0.93 0.0082 0.26 0.96 1.3358 0.9998 SpOx1.1_004966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B17 compound treatment 0.0055 0.257 0.95 0.0102 0.262 0.97 1.3594 0.9999 SpOx1.1_004967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B18 compound treatment 0.0055 0.257 0.95 0.0112 0.263 0.97 1.362 0.9999 SpOx1.1_004968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B19 compound treatment 6.0E-4 0.252 0.93 0.0032 0.255 0.94 1.3281 1.0 SpOx1.1_004969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B20 compound treatment -4.0E-4 0.251 0.93 0.0072 0.259 0.96 1.336 0.9999 SpOx1.1_004970 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B21 compound treatment -0.0014 0.25 0.93 0.0062 0.258 0.96 1.3307 0.9999 SpOx1.1_004971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B22 compound treatment -0.0064 0.245 0.91 -0.0058 0.246 0.91 1.2862 1.0 SpOx1.1_004972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B23 mock treatment 0.0135 0.265 0.98 0.0152 0.267 0.99 1.3935 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 B24 mock treatment -0.4971 -0.245 -0.91 -0.4978 -0.246 -0.91 -1.2858 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C01 compound treatment -0.0134 0.238 0.88 -0.0058 0.246 0.91 1.2679 0.9999 SpOx1.1_004973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C02 compound treatment -0.0084 0.243 0.9 -0.0038 0.248 0.92 1.2862 0.9999 SpOx1.1_004974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C03 compound treatment -0.0185 0.233 0.86 -0.0108 0.241 0.89 1.2416 0.9999 SpOx1.1_004975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C04 compound treatment -0.0075 0.244 0.9 -0.0018 0.25 0.93 1.294 0.9999 SpOx1.1_004976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C05 compound treatment 0.0065 0.258 0.96 0.0112 0.263 0.97 1.3646 1.0 SpOx1.1_004977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C06 compound treatment -0.0195 0.232 0.86 -0.0098 0.242 0.9 1.2417 0.9998 SpOx1.1_004978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C07 compound treatment -0.0185 0.233 0.86 -0.0128 0.239 0.89 1.2364 0.9999 SpOx1.1_004979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C08 compound treatment 5.0E-4 0.252 0.93 0.0022 0.254 0.94 1.3253 1.0 SpOx1.1_004980 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C09 compound treatment -0.0155 0.236 0.87 -0.0098 0.242 0.9 1.2521 0.9999 SpOx1.1_004981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C10 compound treatment -0.0195 0.232 0.86 -0.0108 0.241 0.89 1.239 0.9998 SpOx1.1_004982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C11 compound treatment -0.0285 0.223 0.83 -0.0188 0.233 0.86 1.1945 0.9998 SpOx1.1_004983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C12 compound treatment -0.0065 0.245 0.91 0.0012 0.253 0.94 1.3045 0.9999 SpOx1.1_004984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C13 compound treatment -0.0155 0.236 0.87 -0.0118 0.24 0.89 1.2469 1.0 SpOx1.1_004985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C14 compound treatment -0.0205 0.231 0.86 -0.0128 0.239 0.89 1.2312 0.9999 SpOx1.1_004986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C15 compound treatment -0.0185 0.233 0.86 -0.0188 0.233 0.86 1.2207 1.0 SpOx1.1_004987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C16 compound treatment -0.0045 0.247 0.91 0.0022 0.254 0.94 1.3122 0.9999 SpOx1.1_004988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C17 compound treatment -0.0125 0.239 0.89 2.0E-4 0.252 0.93 1.2861 0.9996 SpOx1.1_004989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C18 compound treatment -5.0E-4 0.251 0.93 -8.0E-4 0.251 0.93 1.3148 1.0 SpOx1.1_004990 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C19 compound treatment -0.0095 0.242 0.9 -0.0068 0.245 0.91 1.2757 1.0 SpOx1.1_004991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C20 compound treatment -0.0125 0.239 0.89 -0.0138 0.238 0.88 1.2495 1.0 SpOx1.1_004992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C21 compound treatment -0.0205 0.231 0.86 -0.0088 0.243 0.9 1.2416 0.9997 SpOx1.1_004993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C22 compound treatment -0.0175 0.234 0.87 -0.0118 0.24 0.89 1.2416 0.9999 SpOx1.1_004994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C23 mock treatment -0.0135 0.238 0.88 -0.0158 0.236 0.87 1.2416 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 C24 mock treatment -0.4971 -0.245 -0.91 -0.4978 -0.246 -0.91 -1.2858 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D01 compound treatment -0.0135 0.238 0.88 -0.0068 0.245 0.91 1.2652 0.9999 SpOx1.1_004995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D02 compound treatment -0.0084 0.243 0.9 -0.0058 0.246 0.91 1.281 1.0 SpOx1.1_004996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D03 compound treatment -0.0145 0.237 0.88 -0.0118 0.24 0.89 1.2495 1.0 SpOx1.1_004997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D04 compound treatment -0.0315 0.22 0.81 -0.0198 0.232 0.86 1.184 0.9996 SpOx1.1_004998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D05 compound treatment -0.0185 0.233 0.86 -0.0148 0.237 0.88 1.2312 1.0 SpOx1.1_004999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D06 compound treatment -0.0085 0.243 0.9 -8.0E-4 0.251 0.93 1.294 0.9999 SpOx1.1_005000 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D07 compound treatment -0.0045 0.247 0.91 0.0032 0.255 0.94 1.3149 0.9999 SpOx1.1_005001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D08 compound treatment -0.0115 0.24 0.89 -0.0058 0.246 0.91 1.273 0.9999 SpOx1.1_005002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D09 compound treatment -0.0165 0.235 0.87 -0.0098 0.242 0.9 1.2495 0.9999 SpOx1.1_005003 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D10 compound treatment -0.0134 0.238 0.88 -0.0098 0.242 0.9 1.2574 1.0 SpOx1.1_005004 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D11 compound treatment -5.0E-4 0.251 0.93 0.0052 0.257 0.95 1.3306 0.9999 SpOx1.1_005005 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D12 compound treatment -0.0135 0.238 0.88 -0.0068 0.245 0.91 1.2651 0.9999 SpOx1.1_005006 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D13 compound treatment 0.0025 0.254 0.94 0.0042 0.256 0.95 1.3358 1.0 SpOx1.1_005007 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D14 compound treatment -0.0215 0.23 0.85 -0.0098 0.242 0.9 1.2364 0.9997 SpOx1.1_005008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D15 compound treatment -0.0235 0.228 0.84 -0.0228 0.229 0.85 1.1971 1.0 SpOx1.1_005009 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D16 compound treatment -0.0235 0.228 0.84 -0.0048 0.247 0.92 1.2442 0.9992 SpOx1.1_005010 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D17 compound treatment -0.0255 0.226 0.84 -0.0108 0.241 0.89 1.2234 0.9995 SpOx1.1_005011 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D18 compound treatment -0.0115 0.24 0.89 -0.0028 0.249 0.92 1.2809 0.9998 SpOx1.1_005012 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D19 compound treatment -0.0195 0.232 0.86 -0.0118 0.24 0.89 1.2364 0.9999 SpOx1.1_005013 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D20 compound treatment -0.0065 0.245 0.91 0.0012 0.253 0.94 1.3045 0.9999 SpOx1.1_005014 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D21 compound treatment -0.0225 0.229 0.85 -0.0168 0.235 0.87 1.2155 0.9999 SpOx1.1_005015 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D22 compound treatment 0.0026 0.254 0.94 0.0012 0.253 0.94 1.3281 1.0 SpOx1.1_005016 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D23 mock treatment -0.0065 0.245 0.91 -0.0108 0.241 0.89 1.273 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 D24 mock treatment -0.4981 -0.246 -0.91 -0.4978 -0.246 -0.91 -1.2884 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E01 compound treatment -0.0125 0.239 0.89 -0.0038 0.248 0.92 1.2757 0.9998 SpOx1.1_005017 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E02 compound treatment -0.0044 0.247 0.91 0.0052 0.257 0.95 1.3203 0.9998 SpOx1.1_005018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E03 compound treatment 5.0E-4 0.252 0.93 0.0092 0.261 0.97 1.3437 0.9998 SpOx1.1_005019 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E04 compound treatment -0.0045 0.247 0.91 0.0012 0.253 0.94 1.3097 0.9999 SpOx1.1_005020 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E05 compound treatment -0.0025 0.249 0.92 0.0052 0.257 0.95 1.3253 0.9999 SpOx1.1_005021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E06 compound treatment 0.0015 0.253 0.94 0.0092 0.261 0.97 1.3463 0.9999 SpOx1.1_005022 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E07 compound treatment 0.0025 0.254 0.94 0.0072 0.259 0.96 1.3437 0.9999 SpOx1.1_005023 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E08 compound treatment 0.0075 0.259 0.96 0.0152 0.267 0.99 1.3777 0.9999 SpOx1.1_005024 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E09 compound treatment -0.0045 0.247 0.91 -0.0038 0.248 0.92 1.2965 1.0 SpOx1.1_005025 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E10 compound treatment 0.0045 0.256 0.95 0.0142 0.266 0.99 1.3672 0.9998 SpOx1.1_005026 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E11 compound treatment -0.0245 0.227 0.84 -0.0228 0.229 0.85 1.1945 1.0 SpOx1.1_005027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E12 compound treatment 0.0055 0.257 0.95 0.0062 0.258 0.96 1.3489 1.0 SpOx1.1_005028 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E13 compound treatment 5.0E-4 0.252 0.93 0.0082 0.26 0.96 1.341 0.9999 SpOx1.1_005029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E14 compound treatment -0.0124 0.239 0.89 -0.0068 0.245 0.91 1.2679 0.9999 SpOx1.1_005030 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E15 compound treatment 0.0245 0.276 1.02 0.0282 0.28 1.04 1.4562 1.0 SpOx1.1_005031 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E16 compound treatment -0.0335 0.218 0.81 0.0012 0.253 0.94 1.2338 0.9972 SpOx1.1_005032 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E17 compound treatment -0.0105 0.241 0.89 -0.0068 0.245 0.91 1.2731 1.0 SpOx1.1_005033 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E18 compound treatment 5.0E-4 0.252 0.93 0.0122 0.264 0.98 1.3515 0.9997 SpOx1.1_005034 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E19 compound treatment -0.0075 0.244 0.9 -0.0028 0.249 0.92 1.2913 0.9999 SpOx1.1_005035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E20 compound treatment -0.0125 0.239 0.89 -0.0098 0.242 0.9 1.2599 1.0 SpOx1.1_005036 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E21 compound treatment 0.0015 0.253 0.94 0.0082 0.26 0.96 1.3437 0.9999 SpOx1.1_005037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E22 compound treatment 5.0E-4 0.252 0.93 0.0102 0.262 0.97 1.3463 0.9998 SpOx1.1_005038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E23 mock treatment 0.0036 0.255 0.94 0.0032 0.255 0.94 1.3359 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 E24 mock treatment -0.5011 -0.249 -0.92 -0.4988 -0.247 -0.92 -1.2989 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F01 compound treatment -0.0215 0.23 0.85 -0.0168 0.235 0.87 1.2181 0.9999 SpOx1.1_005039 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F02 compound treatment -0.0044 0.247 0.91 -0.0018 0.25 0.93 1.3019 1.0 SpOx1.1_005040 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F03 compound treatment -0.0045 0.247 0.91 -0.0018 0.25 0.93 1.3018 1.0 SpOx1.1_005041 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F04 compound treatment -0.0185 0.233 0.86 -0.0118 0.24 0.89 1.239 0.9999 SpOx1.1_005042 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F05 compound treatment 0.0145 0.266 0.98 0.0332 0.285 1.06 1.4432 0.9994 SpOx1.1_005043 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F06 compound treatment -0.0075 0.244 0.9 -0.0028 0.249 0.92 1.2913 0.9999 SpOx1.1_005044 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F07 compound treatment -0.0215 0.23 0.85 -0.0178 0.234 0.87 1.2155 1.0 SpOx1.1_005045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F08 compound treatment -0.0025 0.249 0.92 0.0012 0.253 0.94 1.3149 1.0 SpOx1.1_005046 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F09 compound treatment -0.0275 0.224 0.83 -0.0238 0.228 0.84 1.184 1.0 SpOx1.1_005047 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F10 compound treatment 0.0045 0.256 0.95 0.0092 0.261 0.97 1.3541 0.9999 SpOx1.1_005048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F11 compound treatment -0.0175 0.234 0.87 -0.0038 0.248 0.92 1.2626 0.9996 SpOx1.1_005049 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F12 compound treatment 0.0015 0.253 0.94 0.0032 0.255 0.94 1.3306 1.0 SpOx1.1_005050 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F13 compound treatment 0.0045 0.256 0.95 0.0142 0.266 0.99 1.3672 0.9998 SpOx1.1_005051 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F14 compound treatment -0.0045 0.247 0.91 2.0E-4 0.252 0.93 1.307 0.9999 SpOx1.1_005052 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F15 compound treatment -0.0065 0.245 0.91 -0.0038 0.248 0.92 1.2914 1.0 SpOx1.1_005053 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F16 compound treatment -0.0055 0.246 0.91 0.0052 0.257 0.95 1.3175 0.9998 SpOx1.1_005054 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F17 compound treatment -0.0095 0.242 0.9 0.0022 0.254 0.94 1.2992 0.9997 SpOx1.1_005055 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F18 compound treatment -0.0065 0.245 0.91 0.0022 0.254 0.94 1.3071 0.9998 SpOx1.1_005056 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F19 compound treatment -0.0105 0.241 0.89 0.0172 0.269 1.0 1.3359 0.9985 SpOx1.1_005057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F20 compound treatment 0.0085 0.26 0.96 0.0072 0.259 0.96 1.3593 1.0 SpOx1.1_005058 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F21 compound treatment 0.0025 0.254 0.94 -0.0058 0.246 0.91 1.3096 0.9999 SpOx1.1_005059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F22 compound treatment 0.0056 0.257 0.95 0.0012 0.253 0.94 1.3359 1.0 SpOx1.1_005060 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F23 mock treatment 0.0105 0.262 0.97 0.0092 0.261 0.97 1.3699 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 F24 mock treatment -0.4981 -0.246 -0.91 -0.4978 -0.246 -0.91 -1.2884 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G01 compound treatment -0.0085 0.243 0.9 0.0012 0.253 0.94 1.2992 0.9998 SpOx1.1_005061 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G02 compound treatment -0.0135 0.238 0.88 -0.0068 0.245 0.91 1.2652 0.9999 SpOx1.1_005062 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G03 compound treatment -0.0355 0.216 0.8 -0.0298 0.222 0.82 1.1474 0.9999 SpOx1.1_005063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G04 compound treatment -0.0225 0.229 0.85 -0.0138 0.238 0.88 1.2233 0.9998 SpOx1.1_005064 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G05 compound treatment -0.0255 0.226 0.84 -0.0148 0.237 0.88 1.2129 0.9997 SpOx1.1_005065 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G06 compound treatment -0.0235 0.228 0.84 -0.0138 0.238 0.88 1.2207 0.9998 SpOx1.1_005066 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G07 compound treatment -0.0045 0.247 0.91 -0.0048 0.247 0.92 1.2939 1.0 SpOx1.1_005067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G08 compound treatment -0.0025 0.249 0.92 -0.0038 0.248 0.92 1.3018 1.0 SpOx1.1_005068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G09 compound treatment -0.0345 0.217 0.8 -0.0318 0.22 0.82 1.1448 1.0 SpOx1.1_005069 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G10 compound treatment -0.0064 0.245 0.91 -0.0118 0.24 0.89 1.2705 0.9999 SpOx1.1_005070 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G11 compound treatment -0.0185 0.233 0.86 -0.0158 0.236 0.87 1.2286 1.0 SpOx1.1_005071 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G12 compound treatment -0.0065 0.245 0.91 -0.0028 0.249 0.92 1.294 1.0 SpOx1.1_005072 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G13 compound treatment -0.0075 0.244 0.9 -0.0068 0.245 0.91 1.2809 1.0 SpOx1.1_005073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G14 compound treatment -0.0205 0.231 0.86 -0.0208 0.231 0.86 1.2102 1.0 SpOx1.1_005074 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G15 compound treatment -0.0075 0.244 0.9 -0.0068 0.245 0.91 1.2809 1.0 SpOx1.1_005075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G16 compound treatment -0.0115 0.24 0.89 -0.0148 0.237 0.88 1.2495 1.0 SpOx1.1_005076 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G17 compound treatment -0.0095 0.242 0.9 -0.0048 0.247 0.92 1.2808 0.9999 SpOx1.1_005077 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G18 compound treatment -0.0195 0.232 0.86 -0.0088 0.243 0.9 1.2442 0.9997 SpOx1.1_005078 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G19 compound treatment -0.0135 0.238 0.88 -0.0078 0.244 0.9 1.2625 0.9999 SpOx1.1_005079 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G20 compound treatment -0.0205 0.231 0.86 -0.0288 0.223 0.83 1.1893 0.9998 2142689 SpOx1.1_005080 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G21 compound treatment -0.0115 0.24 0.89 -0.0108 0.241 0.89 1.26 1.0 SpOx1.1_005081 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G22 compound treatment -0.0235 0.228 0.84 -0.0228 0.229 0.85 1.1971 1.0 SpOx1.1_005082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G23 mock treatment -0.0145 0.237 0.88 -0.0098 0.242 0.9 1.2547 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 G24 mock treatment -0.4991 -0.247 -0.91 -0.4978 -0.246 -0.91 -1.291 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H01 compound treatment -0.0115 0.24 0.89 -0.0048 0.247 0.92 1.2757 0.9999 SpOx1.1_005083 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H02 compound treatment -0.0255 0.226 0.84 -0.0188 0.233 0.86 1.2024 0.9999 SpOx1.1_005084 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H03 compound treatment -0.0185 0.233 0.86 -0.0048 0.247 0.92 1.2574 0.9996 SpOx1.1_005085 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H04 compound treatment -0.0325 0.219 0.81 -0.0238 0.228 0.84 1.171 0.9998 SpOx1.1_005086 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H05 compound treatment -0.0165 0.235 0.87 -0.0078 0.244 0.9 1.2547 0.9998 SpOx1.1_005087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H06 compound treatment -0.0205 0.231 0.86 -0.0138 0.238 0.88 1.2285 0.9999 SpOx1.1_005088 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H07 compound treatment -0.0095 0.242 0.9 -8.0E-4 0.251 0.93 1.2913 0.9998 SpOx1.1_005089 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H08 compound treatment -0.0225 0.229 0.85 -0.0158 0.236 0.87 1.2181 0.9999 SpOx1.1_005090 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H09 compound treatment -0.0205 0.231 0.86 -0.0118 0.24 0.89 1.2338 0.9998 SpOx1.1_005091 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H10 compound treatment -0.0155 0.236 0.87 -0.0118 0.24 0.89 1.2468 1.0 SpOx1.1_005092 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H11 compound treatment -0.0155 0.236 0.87 -0.0138 0.238 0.88 1.2416 1.0 SpOx1.1_005093 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H12 compound treatment -0.0054 0.246 0.91 -0.0038 0.248 0.92 1.2941 1.0 SpOx1.1_005094 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H13 compound treatment -0.0085 0.243 0.9 -0.0038 0.248 0.92 1.2861 0.9999 SpOx1.1_005095 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H14 compound treatment -0.0105 0.241 0.89 -0.0018 0.25 0.93 1.2862 0.9998 SpOx1.1_005096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H15 compound treatment -0.0104 0.241 0.89 -0.0058 0.246 0.91 1.2758 0.9999 SpOx1.1_005097 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H16 compound treatment -0.0085 0.243 0.9 -0.0038 0.248 0.92 1.2861 0.9999 SpOx1.1_005098 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H17 compound treatment -0.0055 0.246 0.91 0.0032 0.255 0.94 1.3123 0.9998 SpOx1.1_005099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H18 compound treatment -0.0275 0.224 0.83 -0.0208 0.231 0.86 1.1919 0.9999 SpOx1.1_005100 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H19 compound treatment -0.0175 0.234 0.87 -0.0148 0.237 0.88 1.2338 1.0 SpOx1.1_005101 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H20 compound treatment -0.0175 0.234 0.87 -0.0158 0.236 0.87 1.2312 1.0 SpOx1.1_005102 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H21 compound treatment -0.0135 0.238 0.88 -0.0128 0.239 0.89 1.2495 1.0 SpOx1.1_005103 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H22 compound treatment -0.0115 0.24 0.89 -0.0158 0.236 0.87 1.2469 1.0 SpOx1.1_005104 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H23 mock treatment -0.0105 0.241 0.89 -0.0118 0.24 0.89 1.2599 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 H24 mock treatment -0.4981 -0.246 -0.91 -0.4998 -0.248 -0.92 -1.2936 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I01 compound treatment -5.0E-4 0.251 0.93 0.0032 0.255 0.94 1.3253 1.0 SpOx1.1_005105 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I02 compound treatment -0.0145 0.237 0.88 -0.0048 0.247 0.92 1.2678 0.9998 SpOx1.1_005106 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I03 compound treatment 5.0E-4 0.252 0.93 0.0062 0.258 0.96 1.3358 0.9999 SpOx1.1_005107 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I04 compound treatment -0.0225 0.229 0.85 -0.0118 0.24 0.89 1.2286 0.9997 SpOx1.1_005108 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I05 compound treatment -0.1201 0.132 0.49 -0.1178 0.134 0.5 0.6957 1.0 SpOx1.1_005109 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I06 compound treatment -0.0315 0.22 0.81 -0.0248 0.227 0.84 1.171 0.9999 SpOx1.1_005110 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I07 compound treatment -0.0215 0.23 0.85 -0.0238 0.228 0.84 1.1997 1.0 SpOx1.1_005111 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I08 compound treatment -0.0195 0.232 0.86 -0.0138 0.238 0.88 1.2312 0.9999 SpOx1.1_005112 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I09 compound treatment -0.0105 0.241 0.89 -0.0028 0.249 0.92 1.2835 0.9999 SpOx1.1_005113 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I10 compound treatment -0.0035 0.248 0.92 -8.0E-4 0.251 0.93 1.307 1.0 SpOx1.1_005114 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I11 compound treatment -0.0144 0.237 0.88 -0.0118 0.24 0.89 1.2496 1.0 SpOx1.1_005115 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I12 compound treatment -0.0125 0.239 0.89 -0.0268 0.225 0.83 1.2153 0.9996 SpOx1.1_005116 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I13 compound treatment -0.0025 0.249 0.92 -8.0E-4 0.251 0.93 1.3096 1.0 SpOx1.1_005117 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I14 compound treatment -0.0134 0.238 0.88 -0.0098 0.242 0.9 1.2574 1.0 SpOx1.1_005118 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I15 compound treatment -0.0335 0.218 0.81 -0.0268 0.225 0.83 1.1605 0.9999 SpOx1.1_005119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I16 compound treatment -0.0255 0.226 0.84 -0.0248 0.227 0.84 1.1867 1.0 SpOx1.1_005120 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I17 compound treatment 0.0015 0.253 0.94 0.0052 0.257 0.95 1.3358 1.0 SpOx1.1_005121 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I18 compound treatment -5.0E-4 0.251 0.93 0.0122 0.264 0.98 1.3489 0.9997 SpOx1.1_005122 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I19 compound treatment -0.0104 0.241 0.89 -0.0208 0.231 0.86 1.2365 0.9998 SpOx1.1_005123 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I20 compound treatment -0.0175 0.234 0.87 -0.0088 0.243 0.9 1.2494 0.9998 SpOx1.1_005124 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I21 compound treatment -0.0025 0.249 0.92 -0.0068 0.245 0.91 1.2939 1.0 SpOx1.1_005125 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I22 compound treatment -0.0065 0.245 0.91 -0.0098 0.242 0.9 1.2757 1.0 SpOx1.1_005126 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I23 mock treatment 0.0046 0.256 0.95 0.0042 0.256 0.95 1.3412 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 I24 mock treatment -0.4981 -0.246 -0.91 -0.4988 -0.247 -0.92 -1.291 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J01 compound treatment -0.0225 0.229 0.85 -0.0098 0.242 0.9 1.2338 0.9996 SpOx1.1_005127 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J02 compound treatment -0.0395 0.212 0.79 -0.0368 0.215 0.8 1.1186 1.0 SpOx1.1_005128 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J03 compound treatment -0.0185 0.233 0.86 -0.0148 0.237 0.88 1.2312 1.0 SpOx1.1_005129 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J04 compound treatment -0.0175 0.234 0.87 -0.0078 0.244 0.9 1.2521 0.9998 SpOx1.1_005130 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J05 compound treatment -0.0295 0.222 0.82 -0.0208 0.231 0.86 1.1867 0.9998 SpOx1.1_005131 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J06 compound treatment -0.0215 0.23 0.85 -0.0138 0.238 0.88 1.226 0.9998 SpOx1.1_005132 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J07 compound treatment -0.0285 0.223 0.83 -0.0288 0.223 0.83 1.1684 1.0 SpOx1.1_005133 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J08 compound treatment -0.0085 0.243 0.9 -0.0078 0.244 0.9 1.2756 1.0 SpOx1.1_005134 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J09 compound treatment -0.0245 0.227 0.84 -0.0168 0.235 0.87 1.2103 0.9998 SpOx1.1_005135 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J10 compound treatment -0.0155 0.236 0.87 -0.0148 0.237 0.88 1.239 1.0 SpOx1.1_005136 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J11 compound treatment -0.0154 0.236 0.87 -0.0078 0.244 0.9 1.2574 0.9999 SpOx1.1_005137 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J12 compound treatment -0.0114 0.24 0.89 -0.0118 0.24 0.89 1.2574 1.0 SpOx1.1_005138 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J13 compound treatment -0.0375 0.214 0.79 -0.0338 0.218 0.81 1.1317 1.0 SpOx1.1_005139 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J14 compound treatment -0.0145 0.237 0.88 -0.0118 0.24 0.89 1.2495 1.0 SpOx1.1_005140 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J15 compound treatment -0.0134 0.238 0.88 -0.0068 0.245 0.91 1.2653 0.9999 SpOx1.1_005141 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J16 compound treatment -0.0144 0.237 0.88 -0.0098 0.242 0.9 1.2548 0.9999 SpOx1.1_005142 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J17 compound treatment -0.0085 0.243 0.9 -0.0088 0.243 0.9 1.273 1.0 SpOx1.1_005143 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J18 compound treatment -0.0155 0.236 0.87 -0.0098 0.242 0.9 1.2521 0.9999 SpOx1.1_005144 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J19 compound treatment -0.0205 0.231 0.86 -0.0298 0.222 0.82 1.1866 0.9998 SpOx1.1_005145 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J20 compound treatment -0.0015 0.25 0.93 -0.0048 0.247 0.92 1.3018 1.0 SpOx1.1_005146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J21 compound treatment -0.0035 0.248 0.92 -0.0098 0.242 0.9 1.2834 0.9999 SpOx1.1_005147 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J22 compound treatment -0.0065 0.245 0.91 -0.0038 0.248 0.92 1.2914 1.0 SpOx1.1_005148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J23 mock treatment -0.0085 0.243 0.9 -0.0078 0.244 0.9 1.2756 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 J24 mock treatment -0.4981 -0.246 -0.91 -0.4978 -0.246 -0.91 -1.2884 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K01 compound treatment -0.0025 0.249 0.92 0.0102 0.262 0.97 1.3384 0.9997 SpOx1.1_005149 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K02 compound treatment -0.0134 0.238 0.88 -0.0058 0.246 0.91 1.2679 0.9999 SpOx1.1_005150 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K03 compound treatment -0.0245 0.227 0.84 -0.0048 0.247 0.92 1.2417 0.9991 SpOx1.1_005151 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K04 compound treatment -0.0245 0.227 0.84 -0.0218 0.23 0.85 1.1972 1.0 SpOx1.1_005152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K05 compound treatment -0.0205 0.231 0.86 -0.0168 0.235 0.87 1.2207 1.0 SpOx1.1_005153 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K06 compound treatment -0.0065 0.245 0.91 -0.0048 0.247 0.92 1.2887 1.0 SpOx1.1_005154 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K07 compound treatment -0.0515 0.2 0.74 -0.0538 0.198 0.73 1.0426 1.0 SpOx1.1_005155 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K08 compound treatment -0.0205 0.231 0.86 -0.0208 0.231 0.86 1.2102 1.0 SpOx1.1_005156 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K09 compound treatment -0.0174 0.234 0.87 -0.0188 0.233 0.86 1.2234 1.0 SpOx1.1_005157 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K10 compound treatment -0.0105 0.241 0.89 -0.0108 0.241 0.89 1.2626 1.0 SpOx1.1_005158 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K11 compound treatment -0.0104 0.241 0.89 -0.0118 0.24 0.89 1.26 1.0 SpOx1.1_005159 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K12 compound treatment -0.0125 0.239 0.89 -0.0068 0.245 0.91 1.2678 0.9999 SpOx1.1_005160 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K13 compound treatment -0.0385 0.213 0.79 -0.0358 0.216 0.8 1.1239 1.0 SpOx1.1_005161 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K14 compound treatment -0.0055 0.246 0.91 -0.0018 0.25 0.93 1.2992 1.0 SpOx1.1_005162 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K15 compound treatment -0.0054 0.246 0.91 -0.0018 0.25 0.93 1.2993 1.0 SpOx1.1_005163 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K16 compound treatment -0.0065 0.245 0.91 -0.0038 0.248 0.92 1.2914 1.0 SpOx1.1_005164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K17 compound treatment -0.0245 0.227 0.84 -0.0208 0.231 0.86 1.1998 1.0 SpOx1.1_005165 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K18 compound treatment 0.0025 0.254 0.94 0.0032 0.255 0.94 1.3332 1.0 SpOx1.1_005166 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K19 compound treatment -0.0195 0.232 0.86 -0.0268 0.225 0.83 1.1971 0.9999 SpOx1.1_005167 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K20 compound treatment -0.0185 0.233 0.86 -0.0238 0.228 0.84 1.2076 0.9999 SpOx1.1_005168 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K21 compound treatment -0.0074 0.244 0.9 -0.0148 0.237 0.88 1.26 0.9999 SpOx1.1_005169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K22 compound treatment 0.0055 0.257 0.95 0.0042 0.256 0.95 1.3436 1.0 SpOx1.1_005170 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K23 mock treatment -0.0115 0.24 0.89 -0.0098 0.242 0.9 1.2626 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 K24 mock treatment -0.4971 -0.245 -0.91 -0.4978 -0.246 -0.91 -1.2858 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L01 compound treatment -0.0165 0.235 0.87 -0.0138 0.238 0.88 1.239 1.0 SpOx1.1_005171 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L02 compound treatment -0.0055 0.246 0.91 0.0012 0.253 0.94 1.3071 0.9999 SpOx1.1_005172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L03 compound treatment -0.0025 0.249 0.92 0.0052 0.257 0.95 1.3254 0.9999 SpOx1.1_005173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L04 compound treatment -0.0025 0.249 0.92 0.0062 0.258 0.96 1.328 0.9998 SpOx1.1_005174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L05 compound treatment -0.0265 0.225 0.83 -0.0228 0.229 0.85 1.1892 1.0 SpOx1.1_005175 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L06 compound treatment 0.0035 0.255 0.94 0.0152 0.267 0.99 1.3672 0.9997 SpOx1.1_005176 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L07 compound treatment -0.0104 0.241 0.89 -0.0118 0.24 0.89 1.26 1.0 SpOx1.1_005177 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L08 compound treatment -0.0065 0.245 0.91 -0.0018 0.25 0.93 1.2965 0.9999 SpOx1.1_005178 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L09 compound treatment 0.0115 0.263 0.97 0.0122 0.264 0.98 1.3803 1.0 SpOx1.1_005179 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L10 compound treatment -0.0114 0.24 0.89 -0.0118 0.24 0.89 1.2574 1.0 SpOx1.1_005180 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L11 compound treatment -0.0045 0.247 0.91 -0.0038 0.248 0.92 1.2965 1.0 SpOx1.1_005181 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L12 compound treatment -0.0225 0.229 0.85 -0.0158 0.236 0.87 1.218 0.9999 SpOx1.1_005182 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L13 compound treatment -0.0035 0.248 0.92 0.0042 0.256 0.95 1.3201 0.9999 SpOx1.1_005183 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L14 compound treatment -0.0014 0.25 0.93 0.0042 0.256 0.95 1.3255 0.9999 SpOx1.1_005184 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L15 compound treatment 6.0E-4 0.252 0.93 0.0062 0.258 0.96 1.336 0.9999 SpOx1.1_005185 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L16 compound treatment -0.0035 0.248 0.92 0.0052 0.257 0.95 1.3227 0.9998 SpOx1.1_005186 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L17 compound treatment 0.0105 0.262 0.97 0.0132 0.265 0.98 1.3803 1.0 SpOx1.1_005187 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L18 compound treatment -0.0075 0.244 0.9 -0.0018 0.25 0.93 1.2939 0.9999 SpOx1.1_005188 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L19 compound treatment 0.0085 0.26 0.96 -0.0018 0.25 0.93 1.3358 0.9998 SpOx1.1_005189 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L20 compound treatment 0.0155 0.267 0.99 0.0122 0.264 0.98 1.3907 1.0 SpOx1.1_005190 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L21 compound treatment -0.0065 0.245 0.91 -0.0168 0.235 0.87 1.2572 0.9998 SpOx1.1_005191 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L22 compound treatment 0.0065 0.258 0.96 0.0092 0.261 0.97 1.3594 1.0 SpOx1.1_005192 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L23 mock treatment 0.0145 0.266 0.98 0.0152 0.267 0.99 1.3961 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 L24 mock treatment -0.497 -0.245 -0.91 -0.498 -0.246 -0.91 -1.286 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M01 compound treatment 0.0065 0.258 0.96 0.0092 0.261 0.97 1.3594 1.0 SpOx1.1_005193 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M02 compound treatment 0.0075 0.259 0.96 0.0112 0.263 0.97 1.3672 1.0 SpOx1.1_005194 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M03 compound treatment -0.0024 0.249 0.92 -0.0018 0.25 0.93 1.3072 1.0 SpOx1.1_005195 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M04 compound treatment 0.0035 0.255 0.94 0.0082 0.26 0.96 1.3489 0.9999 SpOx1.1_005196 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M05 compound treatment -0.0115 0.24 0.89 -0.0058 0.246 0.91 1.2731 0.9999 SpOx1.1_005197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M06 compound treatment -0.0205 0.231 0.86 -0.0228 0.229 0.85 1.2049 1.0 SpOx1.1_005198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M07 compound treatment -0.0085 0.243 0.9 -0.0058 0.246 0.91 1.2808 1.0 SpOx1.1_005199 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M08 compound treatment -0.0125 0.239 0.89 -0.0078 0.244 0.9 1.2651 0.9999 SpOx1.1_005200 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M09 compound treatment -0.0125 0.239 0.89 -0.0148 0.237 0.88 1.2468 1.0 SpOx1.1_005201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M10 compound treatment -0.0115 0.24 0.89 -0.0178 0.234 0.87 1.2416 0.9999 SpOx1.1_005202 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M11 compound treatment -0.0055 0.246 0.91 -0.0068 0.245 0.91 1.2861 1.0 SpOx1.1_005203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M12 compound treatment -0.0045 0.247 0.91 -0.0068 0.245 0.91 1.2887 1.0 SpOx1.1_005204 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M13 compound treatment -0.0155 0.236 0.87 -0.0098 0.242 0.9 1.2521 0.9999 SpOx1.1_005205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M14 compound treatment 0.0045 0.256 0.95 0.0052 0.257 0.95 1.3436 1.0 SpOx1.1_005206 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M15 compound treatment -0.0084 0.243 0.9 -0.0058 0.246 0.91 1.281 1.0 SpOx1.1_005207 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M16 compound treatment 5.0E-4 0.252 0.93 0.0032 0.255 0.94 1.3279 1.0 SpOx1.1_005208 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M17 compound treatment -0.0054 0.246 0.91 -0.0118 0.24 0.89 1.2731 0.9999 SpOx1.1_005209 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M18 compound treatment 0.0075 0.259 0.96 0.0082 0.26 0.96 1.3593 1.0 SpOx1.1_005210 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M19 compound treatment 0.0065 0.258 0.96 -0.0018 0.25 0.93 1.3305 0.9999 SpOx1.1_005211 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M20 compound treatment 0.0055 0.257 0.95 0.0062 0.258 0.96 1.3489 1.0 SpOx1.1_005212 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M21 compound treatment -0.0035 0.248 0.92 -0.0048 0.247 0.92 1.2965 1.0 SpOx1.1_005213 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M22 compound treatment -0.0105 0.241 0.89 -0.0118 0.24 0.89 1.2599 1.0 SpOx1.1_005214 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M23 mock treatment 0.0075 0.259 0.96 0.0122 0.264 0.98 1.3699 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 M24 mock treatment -0.4981 -0.246 -0.91 -0.4978 -0.246 -0.91 -1.2884 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N01 compound treatment -0.0315 0.22 0.81 -0.0228 0.229 0.85 1.1762 0.9998 SpOx1.1_005215 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N02 compound treatment -0.0265 0.225 0.83 -0.0238 0.228 0.84 1.1866 1.0 SpOx1.1_005216 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N03 compound treatment -0.0045 0.247 0.91 2.0E-4 0.252 0.93 1.307 0.9999 SpOx1.1_005217 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N04 compound treatment -0.0155 0.236 0.87 -0.0128 0.239 0.89 1.2442 1.0 SpOx1.1_005218 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N05 compound treatment -0.0165 0.235 0.87 -0.0148 0.237 0.88 1.2364 1.0 SpOx1.1_005219 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N06 compound treatment -0.0335 0.218 0.81 -0.0368 0.215 0.8 1.1343 1.0 SpOx1.1_005220 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N07 compound treatment -0.0355 0.216 0.8 -0.0318 0.22 0.82 1.1421 1.0 SpOx1.1_005221 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N08 compound treatment -0.0445 0.207 0.77 -0.0388 0.213 0.79 1.1002 0.9999 SpOx1.1_005222 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N09 compound treatment -0.0355 0.216 0.8 -0.0428 0.209 0.77 1.1133 0.9999 SpOx1.1_005223 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N10 compound treatment -0.0085 0.243 0.9 -0.0038 0.248 0.92 1.2861 0.9999 SpOx1.1_005224 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N11 compound treatment -0.0195 0.232 0.86 -0.0188 0.233 0.86 1.2181 1.0 SpOx1.1_005225 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N12 compound treatment 5.0E-4 0.252 0.93 0.0012 0.253 0.94 1.3227 1.0 SpOx1.1_005226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N13 compound treatment -0.0125 0.239 0.89 -0.0028 0.249 0.92 1.2782 0.9998 SpOx1.1_005227 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N14 compound treatment -0.0035 0.248 0.92 0.0062 0.258 0.96 1.3254 0.9998 SpOx1.1_005228 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N15 compound treatment -0.0175 0.234 0.87 -0.0158 0.236 0.87 1.2312 1.0 SpOx1.1_005229 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N16 compound treatment -0.0175 0.234 0.87 0.0032 0.255 0.94 1.2809 0.9991 SpOx1.1_005230 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N17 compound treatment -0.0144 0.237 0.88 -0.0148 0.237 0.88 1.2417 1.0 SpOx1.1_005231 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N18 compound treatment 5.0E-4 0.252 0.93 2.0E-4 0.252 0.93 1.3201 1.0 SpOx1.1_005232 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N19 compound treatment -0.0144 0.237 0.88 -0.0178 0.234 0.87 1.2339 1.0 SpOx1.1_005233 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N20 compound treatment -0.0065 0.245 0.91 -0.0078 0.244 0.9 1.2808 1.0 SpOx1.1_005234 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N21 compound treatment 0.0095 0.261 0.97 0.0132 0.265 0.98 1.3777 1.0 SpOx1.1_005235 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N22 compound treatment -5.0E-4 0.251 0.93 0.0062 0.258 0.96 1.3332 0.9999 SpOx1.1_005236 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N23 mock treatment 0.0056 0.257 0.95 0.0112 0.263 0.97 1.3621 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 N24 mock treatment -0.4981 -0.246 -0.91 -0.5018 -0.25 -0.93 -1.2989 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O01 compound treatment -0.0315 0.22 0.81 -0.0088 0.243 0.9 1.2129 0.9988 SpOx1.1_005237 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O02 compound treatment 0.0045 0.256 0.95 0.0072 0.259 0.96 1.3489 1.0 SpOx1.1_005238 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O03 compound treatment -0.0155 0.236 0.87 -0.0248 0.227 0.84 1.2127 0.9998 SpOx1.1_005239 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O04 compound treatment -0.0075 0.244 0.9 -0.0098 0.242 0.9 1.273 1.0 SpOx1.1_005240 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O05 compound treatment -0.0085 0.243 0.9 -0.0188 0.233 0.86 1.2468 0.9998 SpOx1.1_005241 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O06 compound treatment -0.0325 0.219 0.81 -0.0388 0.213 0.79 1.1316 0.9999 SpOx1.1_005242 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O07 compound treatment -0.0195 0.232 0.86 -0.0198 0.232 0.86 1.2155 1.0 SpOx1.1_005243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O08 compound treatment -0.0015 0.25 0.93 -8.0E-4 0.251 0.93 1.3122 1.0 SpOx1.1_005244 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O09 compound treatment -0.0075 0.244 0.9 -0.0048 0.247 0.92 1.2861 1.0 SpOx1.1_005245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O10 compound treatment -0.0175 0.234 0.87 -0.0218 0.23 0.85 1.2155 1.0 SpOx1.1_005246 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O11 compound treatment -0.0135 0.238 0.88 -0.0098 0.242 0.9 1.2574 1.0 SpOx1.1_005247 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O12 compound treatment -0.0045 0.247 0.91 -0.0018 0.25 0.93 1.3018 1.0 SpOx1.1_005248 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O13 compound treatment -0.0135 0.238 0.88 -0.0078 0.244 0.9 1.2626 0.9999 SpOx1.1_005249 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O14 compound treatment -0.0055 0.246 0.91 -8.0E-4 0.251 0.93 1.3019 0.9999 SpOx1.1_005250 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O15 compound treatment 0.0135 0.265 0.98 0.0132 0.265 0.98 1.3881 1.0 SpOx1.1_005251 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O16 compound treatment -0.0094 0.242 0.9 -0.0088 0.243 0.9 1.2705 1.0 SpOx1.1_005252 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O17 compound treatment -0.0055 0.246 0.91 -0.0088 0.243 0.9 1.2808 1.0 SpOx1.1_005253 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O18 compound treatment 0.0025 0.254 0.94 -0.0058 0.246 0.91 1.3096 0.9999 SpOx1.1_005254 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O19 compound treatment -0.0075 0.244 0.9 -0.0128 0.239 0.89 1.2652 0.9999 SpOx1.1_005255 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O20 compound treatment -0.0205 0.231 0.86 -0.0238 0.228 0.84 1.2024 1.0 SpOx1.1_005256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O21 compound treatment 0.0115 0.263 0.97 0.0112 0.263 0.97 1.3777 1.0 SpOx1.1_005257 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O22 compound treatment 0.0075 0.259 0.96 0.0052 0.257 0.95 1.3515 1.0 SpOx1.1_005258 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O23 mock treatment 0.0165 0.268 0.99 0.0192 0.271 1.0 1.4117 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 O24 mock treatment -0.4981 -0.246 -0.91 -0.4988 -0.247 -0.92 -1.291 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P01 compound treatment -0.0325 0.219 0.81 -0.0338 0.218 0.81 1.1448 1.0 SpOx1.1_005259 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P02 compound treatment -0.0245 0.227 0.84 -0.0128 0.239 0.89 1.2207 0.9997 SpOx1.1_005260 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P03 compound treatment -0.0315 0.22 0.81 -0.0288 0.223 0.83 1.1604 1.0 SpOx1.1_005261 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P04 compound treatment -0.0185 0.233 0.86 -0.0218 0.23 0.85 1.2128 1.0 SpOx1.1_005262 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P05 compound treatment -0.0675 0.184 0.68 -0.0708 0.181 0.67 0.9563 1.0 SpOx1.1_005263 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P06 compound treatment -0.0135 0.238 0.88 -0.0158 0.236 0.87 1.2416 1.0 SpOx1.1_005264 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P07 compound treatment -0.0385 0.213 0.79 -0.0368 0.215 0.8 1.1212 1.0 SpOx1.1_005265 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P08 compound treatment -0.0415 0.21 0.78 -0.0398 0.212 0.79 1.1055 1.0 SpOx1.1_005266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P09 compound treatment -0.0255 0.226 0.84 -0.0218 0.23 0.85 1.1945 1.0 SpOx1.1_005267 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P10 compound treatment -0.0225 0.229 0.85 -0.0178 0.234 0.87 1.2129 0.9999 SpOx1.1_005268 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P11 compound treatment -0.0415 0.21 0.78 -0.0408 0.211 0.78 1.1028 1.0 SpOx1.1_005269 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P12 compound treatment -0.0275 0.224 0.83 -0.0208 0.231 0.86 1.1918 0.9999 SpOx1.1_005270 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P13 compound treatment -0.0155 0.236 0.87 -0.0108 0.241 0.89 1.2495 0.9999 SpOx1.1_005271 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P14 compound treatment -0.0074 0.244 0.9 -0.0048 0.247 0.92 1.2862 1.0 SpOx1.1_005272 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P15 compound treatment -0.0305 0.221 0.82 -0.0258 0.226 0.84 1.171 0.9999 SpOx1.1_005273 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P16 compound treatment -0.0195 0.232 0.86 -0.0198 0.232 0.86 1.2155 1.0 SpOx1.1_005274 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P17 compound treatment -0.0144 0.237 0.88 -0.0178 0.234 0.87 1.2339 1.0 SpOx1.1_005275 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P18 compound treatment -0.0265 0.225 0.83 -0.0338 0.218 0.81 1.1605 0.9999 SpOx1.1_005276 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P19 compound treatment -0.0205 0.231 0.86 -0.0158 0.236 0.87 1.2233 0.9999 SpOx1.1_005277 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P20 compound treatment -0.0085 0.243 0.9 -0.0128 0.239 0.89 1.2626 1.0 SpOx1.1_005278 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P21 compound treatment -0.0185 0.233 0.86 -0.0158 0.236 0.87 1.2286 1.0 SpOx1.1_005279 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P22 compound treatment -0.0265 0.225 0.83 -0.0158 0.236 0.87 1.2076 0.9997 SpOx1.1_005280 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P23 mock treatment -0.0275 0.224 0.83 -0.0208 0.231 0.86 1.1919 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1292 P24 mock treatment -0.4981 -0.246 -0.91 -0.4978 -0.246 -0.91 -1.2884 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A01 compound treatment -0.0706 0.177 0.66 -0.064 0.184 0.68 0.9454 0.9998 SpOx1.1_005281 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A02 compound treatment -0.0626 0.185 0.68 -0.065 0.183 0.68 0.9637 1.0 SpOx1.1_005282 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A03 compound treatment -0.0917 0.156 0.58 -0.0947 0.153 0.57 0.8099 1.0 SpOx1.1_005283 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A04 compound treatment -0.0977 0.15 0.56 -0.0917 0.156 0.58 0.802 0.9998 SpOx1.1_005284 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A05 compound treatment -0.0746 0.173 0.64 -0.079 0.169 0.63 0.8957 0.9999 SpOx1.1_005285 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A06 compound treatment -0.0907 0.157 0.58 -0.0797 0.168 0.62 0.8518 0.9994 SpOx1.1_005286 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A07 compound treatment -0.0987 0.149 0.55 -0.0987 0.149 0.55 0.7811 1.0 SpOx1.1_005287 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A08 compound treatment -0.0786 0.169 0.63 -0.0837 0.164 0.61 0.8729 0.9999 SpOx1.1_005288 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A09 compound treatment -0.0726 0.175 0.65 -0.068 0.18 0.67 0.9298 0.9999 SpOx1.1_005289 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A10 compound treatment -0.0786 0.169 0.63 -0.076 0.172 0.64 0.8931 1.0 SpOx1.1_005290 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A11 compound treatment -0.0696 0.178 0.66 -0.069 0.179 0.66 0.935 1.0 SpOx1.1_005291 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A12 compound treatment -0.0716 0.176 0.65 -0.07 0.178 0.66 0.9271 1.0 SpOx1.1_005292 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A13 compound treatment -0.0887 0.159 0.59 -0.0807 0.167 0.62 0.8544 0.9997 SpOx1.1_005293 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A14 compound treatment -0.0766 0.171 0.63 -0.0847 0.163 0.61 0.8755 0.9997 SpOx1.1_005294 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A15 compound treatment -0.0816 0.166 0.61 -0.082 0.166 0.62 0.8695 1.0 SpOx1.1_005295 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A16 compound treatment -0.0766 0.171 0.63 -0.076 0.172 0.64 0.8983 1.0 SpOx1.1_005296 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A17 compound treatment -0.0877 0.16 0.59 -0.0817 0.166 0.62 0.8544 0.9998 SpOx1.1_005297 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A18 compound treatment -0.0776 0.17 0.63 -0.073 0.175 0.65 0.9036 0.9999 SpOx1.1_005298 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A19 compound treatment -0.0786 0.169 0.63 -0.08 0.168 0.62 0.8826 1.0 2144451 SpOx1.1_005299 COC(=O)[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A20 compound treatment -0.0827 0.165 0.61 -0.0857 0.162 0.6 0.857 1.0 SpOx1.1_005300 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A21 compound treatment -0.0716 0.176 0.65 -0.071 0.177 0.66 0.9245 1.0 SpOx1.1_005301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A22 compound treatment -0.0826 0.165 0.61 -0.078 0.17 0.63 0.8774 0.9999 SpOx1.1_005302 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A23 mock treatment -0.0756 0.172 0.64 -0.076 0.172 0.64 0.9009 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 A24 mock treatment -0.4889 -0.241 -0.89 -0.4883 -0.24 -0.89 -1.26 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B01 compound treatment -0.0156 0.232 0.86 -0.015 0.233 0.86 1.2178 1.0 SpOx1.1_005303 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B02 compound treatment -0.0126 0.235 0.87 -0.008 0.24 0.89 1.244 0.9999 SpOx1.1_005304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B03 compound treatment 0.0054 0.253 0.94 0.007 0.255 0.94 1.3301 1.0 SpOx1.1_005305 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B04 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2413 1.0 SpOx1.1_005306 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B05 compound treatment 0.0024 0.25 0.93 0.003 0.251 0.93 1.312 1.0 SpOx1.1_005307 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B06 compound treatment -0.0236 0.224 0.83 -0.026 0.222 0.82 1.168 1.0 SpOx1.1_005308 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B07 compound treatment -0.0106 0.237 0.88 -0.01 0.238 0.88 1.244 1.0 SpOx1.1_005309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B08 compound treatment 0.0144 0.262 0.97 0.012 0.26 0.96 1.3668 1.0 SpOx1.1_005310 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B09 compound treatment 0.0064 0.254 0.94 0.008 0.256 0.95 1.3354 1.0 SpOx1.1_005311 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B10 compound treatment 0.0074 0.255 0.94 0.006 0.254 0.94 1.3329 1.0 SpOx1.1_005312 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B11 compound treatment -0.0056 0.242 0.9 -0.008 0.24 0.89 1.2622 1.0 SpOx1.1_005313 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B12 compound treatment -0.0046 0.243 0.9 -0.007 0.241 0.89 1.2675 1.0 SpOx1.1_005314 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B13 compound treatment 4.0E-4 0.248 0.92 0.002 0.25 0.93 1.3041 1.0 SpOx1.1_005315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B14 compound treatment -0.0096 0.238 0.88 -0.005 0.243 0.9 1.2596 0.9999 SpOx1.1_005316 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B15 compound treatment -0.0116 0.236 0.87 -0.009 0.239 0.89 1.2439 1.0 SpOx1.1_005317 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B16 compound treatment -0.0076 0.24 0.89 -0.006 0.242 0.9 1.2623 1.0 SpOx1.1_005318 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B17 compound treatment -6.0E-4 0.247 0.91 0.0 0.248 0.92 1.2963 1.0 SpOx1.1_005319 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B18 compound treatment 4.0E-4 0.248 0.92 0.001 0.249 0.92 1.3015 1.0 SpOx1.1_005320 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B19 compound treatment 0.0014 0.249 0.92 0.001 0.249 0.92 1.304 1.0 SpOx1.1_005321 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B20 compound treatment -0.0016 0.246 0.91 0.003 0.251 0.93 1.3015 0.9999 SpOx1.1_005322 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B21 compound treatment 0.0104 0.258 0.95 0.02 0.268 0.99 1.3773 0.9998 SpOx1.1_005323 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B22 compound treatment -0.0056 0.242 0.9 -0.004 0.244 0.9 1.2727 1.0 SpOx1.1_005324 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B23 mock treatment -0.0056 0.242 0.9 -0.007 0.241 0.89 1.2649 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 B24 mock treatment -0.4889 -0.241 -0.89 -0.4873 -0.239 -0.89 -1.2573 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C01 compound treatment -0.0126 0.235 0.87 -0.01 0.238 0.88 1.2385 1.0 SpOx1.1_005325 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C02 compound treatment -0.0156 0.232 0.86 -0.012 0.236 0.87 1.2255 1.0 SpOx1.1_005326 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C03 compound treatment -0.0336 0.214 0.79 -0.033 0.215 0.8 1.1234 1.0 SpOx1.1_005327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C04 compound treatment -0.0196 0.228 0.84 -0.014 0.234 0.87 1.2098 0.9999 SpOx1.1_005328 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C05 compound treatment -0.0216 0.226 0.84 -0.024 0.224 0.83 1.1783 1.0 SpOx1.1_005329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C06 compound treatment -0.0076 0.24 0.89 -0.007 0.241 0.89 1.2596 1.0 SpOx1.1_005330 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C07 compound treatment -0.0026 0.245 0.91 0.005 0.253 0.94 1.3041 0.9999 SpOx1.1_005331 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C08 compound treatment 0.0014 0.249 0.92 -0.001 0.247 0.92 1.2988 1.0 SpOx1.1_005332 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C09 compound treatment -0.0086 0.239 0.88 -0.009 0.239 0.89 1.2518 1.0 SpOx1.1_005333 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C10 compound treatment -0.0056 0.242 0.9 -0.006 0.242 0.9 1.2674 1.0 SpOx1.1_005334 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C11 compound treatment -0.0096 0.238 0.88 -0.007 0.241 0.89 1.2544 1.0 SpOx1.1_005335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C12 compound treatment -0.0086 0.239 0.88 -0.004 0.244 0.9 1.2649 0.9999 SpOx1.1_005336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C13 compound treatment -0.0096 0.238 0.88 -0.005 0.243 0.9 1.2596 0.9999 SpOx1.1_005337 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C14 compound treatment -0.0066 0.241 0.89 -0.005 0.243 0.9 1.2675 1.0 SpOx1.1_005338 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C15 compound treatment -0.0056 0.242 0.9 -0.005 0.243 0.9 1.2702 1.0 SpOx1.1_005339 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C16 compound treatment -0.0056 0.242 0.9 -0.003 0.245 0.91 1.2753 1.0 SpOx1.1_005340 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C17 compound treatment -0.0046 0.243 0.9 -0.003 0.245 0.91 1.2779 1.0 SpOx1.1_005341 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C18 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2414 1.0 SpOx1.1_005342 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C19 compound treatment -0.0026 0.245 0.91 -0.006 0.242 0.9 1.2752 1.0 SpOx1.1_005343 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C20 compound treatment -0.0096 0.238 0.88 -0.013 0.235 0.87 1.2387 1.0 SpOx1.1_005344 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C21 compound treatment 0.0044 0.252 0.93 0.0 0.248 0.92 1.3093 1.0 SpOx1.1_005345 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C22 compound treatment -0.0136 0.234 0.87 -0.012 0.236 0.87 1.2308 1.0 SpOx1.1_005346 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C23 mock treatment -0.0196 0.228 0.84 -0.025 0.223 0.83 1.1809 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 C24 mock treatment -0.4889 -0.241 -0.89 -0.4883 -0.24 -0.89 -1.26 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D01 compound treatment -0.0156 0.232 0.86 -0.012 0.236 0.87 1.2256 1.0 SpOx1.1_005347 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D02 compound treatment -0.0116 0.236 0.87 -0.013 0.235 0.87 1.2334 1.0 SpOx1.1_005348 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D03 compound treatment -0.0096 0.238 0.88 -0.01 0.238 0.88 1.2466 1.0 SpOx1.1_005349 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D04 compound treatment 0.0014 0.249 0.92 0.002 0.25 0.93 1.3066 1.0 SpOx1.1_005350 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D05 compound treatment -0.0116 0.236 0.87 -0.012 0.236 0.87 1.2361 1.0 SpOx1.1_005351 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D06 compound treatment -0.0106 0.237 0.88 -0.015 0.233 0.86 1.2309 1.0 SpOx1.1_005352 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D07 compound treatment -0.0066 0.241 0.89 -0.009 0.239 0.89 1.2571 1.0 SpOx1.1_005353 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D08 compound treatment -0.0066 0.241 0.89 -0.011 0.237 0.88 1.2517 1.0 SpOx1.1_005354 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D09 compound treatment -0.0256 0.222 0.82 -0.023 0.225 0.83 1.1705 1.0 SpOx1.1_005355 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D10 compound treatment -0.0216 0.226 0.84 -0.022 0.226 0.84 1.1838 1.0 SpOx1.1_005356 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D11 compound treatment 0.0014 0.249 0.92 0.0 0.248 0.92 1.3014 1.0 SpOx1.1_005357 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D12 compound treatment -0.0046 0.243 0.9 -0.002 0.246 0.91 1.2805 1.0 SpOx1.1_005358 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D13 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2413 1.0 SpOx1.1_005359 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D14 compound treatment 0.0074 0.255 0.94 0.01 0.258 0.96 1.3432 1.0 SpOx1.1_005360 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D15 compound treatment -0.0216 0.226 0.84 -0.021 0.227 0.84 1.1864 1.0 SpOx1.1_005361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D16 compound treatment -0.0046 0.243 0.9 -0.005 0.243 0.9 1.2726 1.0 SpOx1.1_005362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D17 compound treatment -0.0026 0.245 0.91 -0.007 0.241 0.89 1.2726 1.0 SpOx1.1_005363 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D18 compound treatment -0.0046 0.243 0.9 -0.009 0.239 0.89 1.2621 1.0 SpOx1.1_005364 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D19 compound treatment -0.0136 0.234 0.87 -0.012 0.236 0.87 1.2308 1.0 SpOx1.1_005365 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D20 compound treatment -0.0186 0.229 0.85 -0.025 0.223 0.83 1.1838 0.9999 SpOx1.1_005366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D21 compound treatment -0.0216 0.226 0.84 -0.018 0.23 0.85 1.1943 1.0 SpOx1.1_005367 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D22 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2414 1.0 SpOx1.1_005368 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D23 mock treatment 0.0074 0.255 0.94 0.001 0.249 0.92 1.3198 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 D24 mock treatment -0.4889 -0.241 -0.89 -0.4863 -0.238 -0.88 -1.2547 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E01 compound treatment 4.0E-4 0.248 0.92 0.007 0.255 0.94 1.317 0.9999 SpOx1.1_005369 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E02 compound treatment 0.0044 0.252 0.93 0.004 0.252 0.93 1.3197 1.0 SpOx1.1_005370 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E03 compound treatment 0.0014 0.249 0.92 0.0 0.248 0.92 1.3014 1.0 SpOx1.1_005371 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E04 compound treatment -0.0106 0.237 0.88 -0.012 0.236 0.87 1.2387 1.0 SpOx1.1_005372 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E05 compound treatment -0.0026 0.245 0.91 -0.004 0.244 0.9 1.2805 1.0 SpOx1.1_005373 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E06 compound treatment -0.0026 0.245 0.91 0.001 0.249 0.92 1.2936 1.0 SpOx1.1_005374 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E07 compound treatment -0.0036 0.244 0.9 0.001 0.249 0.92 1.2909 0.9999 SpOx1.1_005375 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E08 compound treatment 0.0014 0.249 0.92 0.003 0.251 0.93 1.3093 1.0 SpOx1.1_005376 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E09 compound treatment -0.0036 0.244 0.9 0.0 0.248 0.92 1.2884 1.0 SpOx1.1_005377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E10 compound treatment 0.0114 0.259 0.96 0.013 0.261 0.97 1.3616 1.0 SpOx1.1_005378 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E11 compound treatment -0.0046 0.243 0.9 -0.003 0.245 0.91 1.2779 1.0 SpOx1.1_005379 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E12 compound treatment -0.0196 0.228 0.84 -0.023 0.225 0.83 1.1862 1.0 SpOx1.1_005380 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E13 compound treatment -6.0E-4 0.247 0.91 -0.004 0.244 0.9 1.2857 1.0 SpOx1.1_005381 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E14 compound treatment -0.0066 0.241 0.89 -0.01 0.238 0.88 1.2543 1.0 SpOx1.1_005382 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E15 compound treatment -6.0E-4 0.247 0.91 0.002 0.25 0.93 1.3014 1.0 SpOx1.1_005383 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E16 compound treatment -6.0E-4 0.247 0.91 0.001 0.249 0.92 1.2988 1.0 SpOx1.1_005384 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E17 compound treatment 0.0084 0.256 0.95 0.007 0.255 0.94 1.338 1.0 SpOx1.1_005385 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E18 compound treatment 0.0024 0.25 0.93 0.006 0.254 0.94 1.3197 1.0 SpOx1.1_005386 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E19 compound treatment 0.0024 0.25 0.93 0.0 0.248 0.92 1.304 1.0 SpOx1.1_005387 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E20 compound treatment -0.0076 0.24 0.89 0.004 0.252 0.93 1.2883 0.9997 SpOx1.1_005388 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E21 compound treatment 0.0034 0.251 0.93 0.002 0.25 0.93 1.3119 1.0 SpOx1.1_005389 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E22 compound treatment 0.0044 0.252 0.93 0.002 0.25 0.93 1.3146 1.0 SpOx1.1_005390 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E23 mock treatment -0.0026 0.245 0.91 0.001 0.249 0.92 1.2937 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 E24 mock treatment -0.4889 -0.241 -0.89 -0.4873 -0.239 -0.89 -1.2573 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F01 compound treatment -0.0446 0.203 0.75 -0.008 0.24 0.89 1.1602 0.9965 SpOx1.1_005391 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F02 compound treatment -0.0176 0.23 0.85 -0.018 0.23 0.85 1.2046 1.0 SpOx1.1_005392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F03 compound treatment -0.0016 0.246 0.91 -0.008 0.24 0.89 1.2726 0.9999 SpOx1.1_005393 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F04 compound treatment -0.0076 0.24 0.89 -0.015 0.233 0.86 1.2386 0.9999 SpOx1.1_005394 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F05 compound treatment -0.0156 0.232 0.86 -0.01 0.238 0.88 1.2309 0.9999 SpOx1.1_005395 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F06 compound treatment 0.0024 0.25 0.93 -0.002 0.246 0.91 1.2988 1.0 SpOx1.1_005396 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F07 compound treatment -0.0086 0.239 0.88 -0.006 0.242 0.9 1.2597 1.0 SpOx1.1_005397 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F08 compound treatment -0.0316 0.216 0.8 -0.026 0.222 0.82 1.147 0.9999 SpOx1.1_005398 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F09 compound treatment 0.0034 0.251 0.93 0.008 0.256 0.95 1.3275 0.9999 SpOx1.1_005399 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F10 compound treatment 0.0024 0.25 0.93 0.005 0.253 0.94 1.3172 1.0 SpOx1.1_005400 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F11 compound treatment -0.0046 0.243 0.9 -0.001 0.247 0.92 1.2832 1.0 SpOx1.1_005401 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F12 compound treatment -0.0146 0.233 0.86 -0.008 0.24 0.89 1.2387 0.9999 SpOx1.1_005402 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F13 compound treatment 0.0074 0.255 0.94 0.002 0.25 0.93 1.3223 1.0 SpOx1.1_005403 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F14 compound treatment 0.0054 0.253 0.94 0.01 0.258 0.96 1.3381 0.9999 SpOx1.1_005404 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F15 compound treatment -0.0026 0.245 0.91 -0.003 0.245 0.91 1.2831 1.0 SpOx1.1_005405 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F16 compound treatment 0.0104 0.258 0.95 0.012 0.26 0.96 1.3564 1.0 SpOx1.1_005406 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F17 compound treatment -0.0036 0.244 0.9 -0.005 0.243 0.9 1.2752 1.0 SpOx1.1_005407 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F18 compound treatment 0.0104 0.258 0.95 0.009 0.257 0.95 1.3485 1.0 SpOx1.1_005408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F19 compound treatment -0.0036 0.244 0.9 -0.005 0.243 0.9 1.2752 1.0 SpOx1.1_005409 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F20 compound treatment -6.0E-4 0.247 0.91 -0.002 0.246 0.91 1.2909 1.0 SpOx1.1_005410 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F21 compound treatment 0.0054 0.253 0.94 0.003 0.251 0.93 1.3197 1.0 SpOx1.1_005411 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F22 compound treatment 4.0E-4 0.248 0.92 0.003 0.251 0.93 1.3066 1.0 SpOx1.1_005412 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F23 mock treatment -0.0076 0.24 0.89 -0.011 0.237 0.88 1.249 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 F24 mock treatment -0.494 -0.246 -0.91 -0.488 -0.24 -0.89 -1.2725 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G01 compound treatment -0.0276 0.22 0.81 -0.025 0.223 0.83 1.16 1.0 SpOx1.1_005413 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G02 compound treatment -0.0156 0.232 0.86 -0.013 0.235 0.87 1.223 1.0 SpOx1.1_005414 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G03 compound treatment -0.0326 0.215 0.8 -0.019 0.229 0.85 1.1627 0.9995 SpOx1.1_005415 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G04 compound treatment -0.0056 0.242 0.9 -0.011 0.237 0.88 1.2544 1.0 2142371 SpOx1.1_005416 COC(=O)[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G05 compound treatment -0.0096 0.238 0.88 -0.012 0.236 0.87 1.2412 1.0 SpOx1.1_005417 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G06 compound treatment 0.0014 0.249 0.92 -0.006 0.242 0.9 1.2857 0.9999 SpOx1.1_005418 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G07 compound treatment -0.0016 0.246 0.91 -0.002 0.246 0.91 1.2883 1.0 SpOx1.1_005419 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G08 compound treatment -0.0096 0.238 0.88 -0.015 0.233 0.86 1.2335 1.0 SpOx1.1_005420 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G09 compound treatment -0.0026 0.245 0.91 0.002 0.25 0.93 1.2962 0.9999 SpOx1.1_005421 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G10 compound treatment -0.0116 0.236 0.87 -0.011 0.237 0.88 1.2386 1.0 SpOx1.1_005422 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G11 compound treatment -0.0216 0.226 0.84 -0.02 0.228 0.84 1.189 1.0 SpOx1.1_005423 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G12 compound treatment 0.0024 0.25 0.93 0.0 0.248 0.92 1.304 1.0 SpOx1.1_005424 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G13 compound treatment -0.0256 0.222 0.82 -0.024 0.224 0.83 1.1681 1.0 SpOx1.1_005425 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G14 compound treatment -0.0286 0.219 0.81 -0.034 0.214 0.79 1.134 0.9999 SpOx1.1_005426 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G15 compound treatment -0.0236 0.224 0.83 -0.025 0.223 0.83 1.1705 1.0 SpOx1.1_005427 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G16 compound treatment -0.0356 0.212 0.78 -0.036 0.212 0.79 1.1105 1.0 SpOx1.1_005428 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G17 compound treatment -0.0096 0.238 0.88 -0.014 0.234 0.87 1.2361 1.0 SpOx1.1_005429 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G18 compound treatment -0.0096 0.238 0.88 -0.011 0.237 0.88 1.244 1.0 SpOx1.1_005430 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G19 compound treatment -0.0206 0.227 0.84 -0.02 0.228 0.84 1.1916 1.0 SpOx1.1_005431 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G20 compound treatment -0.0716 0.176 0.65 -0.073 0.175 0.65 0.9194 1.0 SpOx1.1_005432 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G21 compound treatment -0.0166 0.231 0.86 -0.018 0.23 0.85 1.2073 1.0 SpOx1.1_005433 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G22 compound treatment -0.0036 0.244 0.9 -0.005 0.243 0.9 1.2753 1.0 SpOx1.1_005434 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G23 mock treatment -0.0076 0.24 0.89 -0.006 0.242 0.9 1.2623 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 G24 mock treatment -0.4889 -0.241 -0.89 -0.4873 -0.239 -0.89 -1.2573 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H01 compound treatment -0.0196 0.228 0.84 -0.013 0.235 0.87 1.2125 0.9999 SpOx1.1_005435 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H02 compound treatment -0.0096 0.238 0.88 -0.012 0.236 0.87 1.2412 1.0 SpOx1.1_005436 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H03 compound treatment -0.0376 0.21 0.78 -0.034 0.214 0.79 1.1103 0.9999 SpOx1.1_005437 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H04 compound treatment -0.0076 0.24 0.89 -0.008 0.24 0.89 1.2571 1.0 SpOx1.1_005438 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H05 compound treatment -0.0076 0.24 0.89 -0.003 0.245 0.91 1.27 0.9999 SpOx1.1_005439 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H06 compound treatment -0.0796 0.168 0.62 -0.075 0.173 0.64 0.8933 0.9999 SpOx1.1_005440 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H07 compound treatment -0.0386 0.209 0.77 -0.032 0.216 0.8 1.113 0.9999 SpOx1.1_005441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H08 compound treatment -0.0176 0.23 0.85 -0.018 0.23 0.85 1.2046 1.0 SpOx1.1_005442 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H09 compound treatment -0.0146 0.233 0.86 -0.014 0.234 0.87 1.2228 1.0 SpOx1.1_005443 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H10 compound treatment 0.0044 0.252 0.93 0.001 0.249 0.92 1.3119 1.0 SpOx1.1_005444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H11 compound treatment -0.0176 0.23 0.85 -0.026 0.222 0.82 1.1838 0.9999 SpOx1.1_005445 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H12 compound treatment -0.0156 0.232 0.86 -0.014 0.234 0.87 1.2204 1.0 SpOx1.1_005446 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H13 compound treatment -0.0306 0.217 0.8 -0.017 0.231 0.86 1.1732 0.9995 SpOx1.1_005447 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H14 compound treatment -0.0026 0.245 0.91 -0.007 0.241 0.89 1.2726 1.0 SpOx1.1_005448 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H15 compound treatment -0.0136 0.234 0.87 -0.016 0.232 0.86 1.2204 1.0 SpOx1.1_005449 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H16 compound treatment -0.0146 0.233 0.86 -0.017 0.231 0.86 1.2152 1.0 SpOx1.1_005450 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H17 compound treatment -0.0216 0.226 0.84 -0.023 0.225 0.83 1.1811 1.0 SpOx1.1_005451 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H18 compound treatment -0.0286 0.219 0.81 -0.027 0.221 0.82 1.1524 1.0 SpOx1.1_005452 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H19 compound treatment -0.0156 0.232 0.86 -0.016 0.232 0.86 1.2152 1.0 SpOx1.1_005453 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H20 compound treatment -0.0196 0.228 0.84 -0.027 0.221 0.82 1.1759 0.9999 SpOx1.1_005454 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H21 compound treatment -0.0146 0.233 0.86 -0.023 0.225 0.83 1.1993 0.9999 SpOx1.1_005455 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H22 compound treatment -0.0096 0.238 0.88 -0.011 0.237 0.88 1.244 1.0 SpOx1.1_005456 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H23 mock treatment 0.0094 0.257 0.95 -0.015 0.233 0.86 1.283 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 H24 mock treatment -0.4909 -0.243 -0.9 -0.4883 -0.24 -0.89 -1.2652 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I01 compound treatment -0.0136 0.234 0.87 -0.018 0.23 0.85 1.2152 1.0 SpOx1.1_005457 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I02 compound treatment -0.0116 0.236 0.87 -0.011 0.237 0.88 1.2386 1.0 SpOx1.1_005458 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I03 compound treatment 0.0024 0.25 0.93 0.0 0.248 0.92 1.304 1.0 SpOx1.1_005459 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I04 compound treatment -0.0256 0.222 0.82 -0.025 0.223 0.83 1.1655 1.0 SpOx1.1_005460 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I05 compound treatment -0.0036 0.244 0.9 0.0 0.248 0.92 1.2883 1.0 SpOx1.1_005461 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I06 compound treatment -0.0136 0.234 0.87 -0.013 0.235 0.87 1.2281 1.0 SpOx1.1_005462 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I07 compound treatment -0.0026 0.245 0.91 -0.003 0.245 0.91 1.2831 1.0 SpOx1.1_005463 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I08 compound treatment -0.0296 0.218 0.81 -0.026 0.222 0.82 1.1524 1.0 SpOx1.1_005464 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I09 compound treatment -0.0196 0.228 0.84 -0.018 0.23 0.85 1.1995 1.0 SpOx1.1_005465 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I10 compound treatment -0.0096 0.238 0.88 -0.01 0.238 0.88 1.2464 1.0 SpOx1.1_005466 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I11 compound treatment -0.0026 0.245 0.91 -0.001 0.247 0.92 1.2884 1.0 SpOx1.1_005467 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I12 compound treatment -0.0166 0.231 0.86 -0.014 0.234 0.87 1.2178 1.0 SpOx1.1_005468 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I13 compound treatment -0.0066 0.241 0.89 -0.008 0.24 0.89 1.2595 1.0 SpOx1.1_005469 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I14 compound treatment -0.0136 0.234 0.87 -0.012 0.236 0.87 1.2309 1.0 SpOx1.1_005470 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I15 compound treatment -0.0166 0.231 0.86 -0.012 0.236 0.87 1.2229 0.9999 SpOx1.1_005471 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I16 compound treatment -0.0186 0.229 0.85 -0.031 0.217 0.8 1.168 0.9997 SpOx1.1_005472 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I17 compound treatment -0.0246 0.223 0.83 -0.025 0.223 0.83 1.1679 1.0 SpOx1.1_005473 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I18 compound treatment -0.0336 0.214 0.79 -0.034 0.214 0.79 1.1208 1.0 SpOx1.1_005474 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I19 compound treatment -0.0016 0.246 0.91 0.001 0.249 0.92 1.2962 1.0 SpOx1.1_005475 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I20 compound treatment -0.0646 0.183 0.68 -0.059 0.189 0.7 0.9744 0.9999 SpOx1.1_005476 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I21 compound treatment -0.0216 0.226 0.84 -0.021 0.227 0.84 1.1864 1.0 SpOx1.1_005477 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I22 compound treatment -6.0E-4 0.247 0.91 0.0 0.248 0.92 1.2962 1.0 SpOx1.1_005478 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I23 mock treatment 4.0E-4 0.248 0.92 0.002 0.25 0.93 1.3042 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 I24 mock treatment -0.4889 -0.241 -0.89 -0.4873 -0.239 -0.89 -1.2573 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J01 compound treatment -0.0206 0.227 0.84 -0.019 0.229 0.85 1.194 1.0 SpOx1.1_005479 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J02 compound treatment -0.0176 0.23 0.85 -0.011 0.237 0.88 1.223 0.9999 SpOx1.1_005480 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J03 compound treatment -0.0486 0.199 0.74 -0.05 0.198 0.73 1.0397 1.0 SpOx1.1_005481 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J04 compound treatment -0.0266 0.221 0.82 -0.022 0.226 0.84 1.1707 0.9999 SpOx1.1_005482 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J05 compound treatment -0.0166 0.231 0.86 -0.014 0.234 0.87 1.2178 1.0 SpOx1.1_005483 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J06 compound treatment -0.0026 0.245 0.91 -0.004 0.244 0.9 1.2805 1.0 SpOx1.1_005484 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J07 compound treatment -0.0236 0.224 0.83 -0.023 0.225 0.83 1.1758 1.0 SpOx1.1_005485 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J08 compound treatment -0.0256 0.222 0.82 -0.018 0.23 0.85 1.1838 0.9998 SpOx1.1_005486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J09 compound treatment -0.0136 0.234 0.87 -0.015 0.233 0.86 1.223 1.0 SpOx1.1_005487 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J10 compound treatment -0.0576 0.19 0.7 -0.059 0.189 0.7 0.9927 1.0 SpOx1.1_005488 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J11 compound treatment -0.0206 0.227 0.84 -0.016 0.232 0.86 1.2021 0.9999 SpOx1.1_005489 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J12 compound treatment -0.0206 0.227 0.84 -0.019 0.229 0.85 1.1942 1.0 SpOx1.1_005490 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J13 compound treatment -0.0296 0.218 0.81 -0.03 0.218 0.81 1.1419 1.0 SpOx1.1_005491 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J14 compound treatment -0.0136 0.234 0.87 -0.019 0.229 0.85 1.2124 0.9999 SpOx1.1_005492 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J15 compound treatment -0.0196 0.228 0.84 -0.017 0.231 0.86 1.2019 1.0 SpOx1.1_005493 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J16 compound treatment -0.0336 0.214 0.79 -0.03 0.218 0.81 1.1314 1.0 SpOx1.1_005494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J17 compound treatment -0.0236 0.224 0.83 -0.022 0.226 0.84 1.1783 1.0 SpOx1.1_005495 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J18 compound treatment -0.0156 0.232 0.86 -0.017 0.231 0.86 1.2124 1.0 SpOx1.1_005496 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J19 compound treatment -0.0096 0.238 0.88 -0.007 0.241 0.89 1.2545 1.0 SpOx1.1_005497 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J20 compound treatment -0.0176 0.23 0.85 -0.022 0.226 0.84 1.1942 1.0 SpOx1.1_005498 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J21 compound treatment -0.0766 0.171 0.63 -0.068 0.18 0.67 0.9194 0.9997 SpOx1.1_005499 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J22 compound treatment -0.0326 0.215 0.8 -0.027 0.221 0.82 1.1419 0.9999 SpOx1.1_005500 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J23 mock treatment -0.0126 0.235 0.87 -0.011 0.237 0.88 1.2359 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 J24 mock treatment -0.4899 -0.242 -0.9 -0.4873 -0.239 -0.89 -1.26 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K01 compound treatment -0.0076 0.24 0.89 -0.005 0.243 0.9 1.2649 1.0 SpOx1.1_005501 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K02 compound treatment -0.0206 0.227 0.84 -0.02 0.228 0.84 1.1916 1.0 SpOx1.1_005502 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K03 compound treatment -0.0106 0.237 0.88 -0.015 0.233 0.86 1.2309 1.0 SpOx1.1_005503 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K04 compound treatment -0.0106 0.237 0.88 -0.01 0.238 0.88 1.2439 1.0 SpOx1.1_005504 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K05 compound treatment -0.0176 0.23 0.85 -0.014 0.234 0.87 1.215 1.0 SpOx1.1_005505 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K06 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2414 1.0 SpOx1.1_005506 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K07 compound treatment -0.0026 0.245 0.91 0.001 0.249 0.92 1.2936 1.0 SpOx1.1_005507 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K08 compound treatment -0.0066 0.241 0.89 -0.002 0.246 0.91 1.2752 0.9999 SpOx1.1_005508 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K09 compound treatment -0.0176 0.23 0.85 -0.012 0.236 0.87 1.2204 0.9999 SpOx1.1_005509 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K10 compound treatment -0.0036 0.244 0.9 -0.003 0.245 0.91 1.2806 1.0 SpOx1.1_005510 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K11 compound treatment -0.0116 0.236 0.87 -0.017 0.231 0.86 1.2231 0.9999 SpOx1.1_005511 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K12 compound treatment -0.0076 0.24 0.89 -0.01 0.238 0.88 1.2518 1.0 SpOx1.1_005512 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K13 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2414 1.0 SpOx1.1_005513 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K14 compound treatment -0.0116 0.236 0.87 -0.009 0.239 0.89 1.2439 1.0 SpOx1.1_005514 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K15 compound treatment -0.0126 0.235 0.87 -0.003 0.245 0.91 1.257 0.9998 SpOx1.1_005515 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K16 compound treatment 0.0014 0.249 0.92 0.005 0.253 0.94 1.3145 1.0 SpOx1.1_005516 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K17 compound treatment -0.0196 0.228 0.84 -0.017 0.231 0.86 1.2021 1.0 SpOx1.1_005517 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K18 compound treatment -0.0266 0.221 0.82 -0.027 0.221 0.82 1.1576 1.0 SpOx1.1_005518 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K19 compound treatment -0.0426 0.205 0.76 -0.044 0.204 0.76 1.0711 1.0 SpOx1.1_005519 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K20 compound treatment -0.0156 0.232 0.86 -0.013 0.235 0.87 1.223 1.0 SpOx1.1_005520 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K21 compound treatment -0.0296 0.218 0.81 -0.028 0.22 0.82 1.1471 1.0 SpOx1.1_005521 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K22 compound treatment 0.0024 0.25 0.93 0.001 0.249 0.92 1.3067 1.0 SpOx1.1_005522 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K23 mock treatment -0.0076 0.24 0.89 -0.008 0.24 0.89 1.257 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 K24 mock treatment -0.4889 -0.241 -0.89 -0.4883 -0.24 -0.89 -1.26 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L01 compound treatment -0.0096 0.238 0.88 -0.014 0.234 0.87 1.236 1.0 SpOx1.1_005523 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L02 compound treatment -6.0E-4 0.247 0.91 0.008 0.256 0.95 1.3171 0.9998 SpOx1.1_005524 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L03 compound treatment 0.0134 0.261 0.97 0.013 0.261 0.97 1.3668 1.0 SpOx1.1_005525 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L04 compound treatment -0.0036 0.244 0.9 -0.001 0.247 0.92 1.2857 1.0 SpOx1.1_005526 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L05 compound treatment -0.0026 0.245 0.91 0.003 0.251 0.93 1.2988 0.9999 SpOx1.1_005527 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L06 compound treatment -0.0126 0.235 0.87 -0.01 0.238 0.88 1.2386 1.0 SpOx1.1_005528 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L07 compound treatment -0.0186 0.229 0.85 -0.015 0.233 0.86 1.21 1.0 SpOx1.1_005529 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L08 compound treatment -0.0146 0.233 0.86 -0.02 0.228 0.84 1.2072 0.9999 SpOx1.1_005530 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L09 compound treatment 0.0024 0.25 0.93 0.002 0.25 0.93 1.3093 1.0 SpOx1.1_005531 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L10 compound treatment 0.0044 0.252 0.93 0.008 0.256 0.95 1.3302 1.0 SpOx1.1_005532 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L11 compound treatment -0.0036 0.244 0.9 -0.005 0.243 0.9 1.2752 1.0 SpOx1.1_005533 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L12 compound treatment -0.0016 0.246 0.91 0.001 0.249 0.92 1.2962 1.0 SpOx1.1_005534 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L13 compound treatment -0.0106 0.237 0.88 -0.012 0.236 0.87 1.2386 1.0 SpOx1.1_005535 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L14 compound treatment -0.0036 0.244 0.9 0.0 0.248 0.92 1.2883 1.0 SpOx1.1_005536 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L15 compound treatment -0.0076 0.24 0.89 -0.003 0.245 0.91 1.2701 0.9999 SpOx1.1_005537 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L16 compound treatment 0.0024 0.25 0.93 0.005 0.253 0.94 1.317 1.0 SpOx1.1_005538 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L17 compound treatment 0.0124 0.26 0.96 0.016 0.264 0.98 1.3721 1.0 SpOx1.1_005539 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L18 compound treatment -0.0016 0.246 0.91 0.0 0.248 0.92 1.2936 1.0 SpOx1.1_005540 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L19 compound treatment 4.0E-4 0.248 0.92 -0.003 0.245 0.91 1.2909 1.0 SpOx1.1_005541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L20 compound treatment 0.0044 0.252 0.93 0.001 0.249 0.92 1.3119 1.0 SpOx1.1_005542 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L21 compound treatment -6.0E-4 0.247 0.91 -0.002 0.246 0.91 1.2909 1.0 SpOx1.1_005543 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L22 compound treatment 0.0104 0.258 0.95 0.014 0.262 0.97 1.3616 1.0 SpOx1.1_005544 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L23 mock treatment 0.0204 0.268 0.99 0.021 0.269 1.0 1.406 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 L24 mock treatment -0.49 -0.242 -0.9 -0.488 -0.24 -0.89 -1.2621 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M01 compound treatment -0.0086 0.239 0.88 -0.014 0.234 0.87 1.2386 1.0 SpOx1.1_005545 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M02 compound treatment -0.0666 0.181 0.67 -0.076 0.172 0.64 0.9246 0.9997 SpOx1.1_005546 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M03 compound treatment 0.0084 0.256 0.95 -0.004 0.244 0.9 1.3092 0.9997 SpOx1.1_005547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M04 compound treatment 0.0044 0.252 0.93 0.006 0.254 0.94 1.325 1.0 SpOx1.1_005548 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M05 compound treatment -0.0066 0.241 0.89 -0.002 0.246 0.91 1.2752 0.9999 SpOx1.1_005549 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M06 compound treatment 0.0024 0.25 0.93 0.004 0.252 0.93 1.3145 1.0 SpOx1.1_005550 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M07 compound treatment 0.0014 0.249 0.92 0.002 0.25 0.93 1.3066 1.0 SpOx1.1_005551 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M08 compound treatment 4.0E-4 0.248 0.92 0.002 0.25 0.93 1.304 1.0 SpOx1.1_005552 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M09 compound treatment -0.0056 0.242 0.9 -0.008 0.24 0.89 1.2621 1.0 SpOx1.1_005553 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M10 compound treatment -0.0236 0.224 0.83 -0.023 0.225 0.83 1.1759 1.0 SpOx1.1_005554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M11 compound treatment -0.0066 0.241 0.89 -0.007 0.241 0.89 1.2621 1.0 SpOx1.1_005555 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M12 compound treatment -0.0106 0.237 0.88 -0.015 0.233 0.86 1.2309 1.0 SpOx1.1_005556 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M13 compound treatment -0.0216 0.226 0.84 -0.029 0.219 0.81 1.1654 0.9999 2143703 SpOx1.1_005557 COC(=O)[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CC8(O)CCCCCC8)ccc17)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M14 compound treatment 4.0E-4 0.248 0.92 0.0 0.248 0.92 1.2988 1.0 SpOx1.1_005558 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M15 compound treatment -0.0166 0.231 0.86 -0.015 0.233 0.86 1.2152 1.0 SpOx1.1_005559 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M16 compound treatment -0.0356 0.212 0.78 -0.036 0.212 0.79 1.1105 1.0 SpOx1.1_005560 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M17 compound treatment -0.0036 0.244 0.9 -0.006 0.242 0.9 1.2726 1.0 SpOx1.1_005561 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M18 compound treatment 0.0044 0.252 0.93 -0.002 0.246 0.91 1.304 0.9999 SpOx1.1_005562 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M19 compound treatment -0.0076 0.24 0.89 -0.01 0.238 0.88 1.2517 1.0 SpOx1.1_005563 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M20 compound treatment -0.0146 0.233 0.86 -0.013 0.235 0.87 1.2255 1.0 2143863 SpOx1.1_005564 COC(=O)[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#Cc8ccc(OC)cc8)ccc17)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M21 compound treatment 0.0144 0.262 0.97 0.002 0.25 0.93 1.3406 0.9997 SpOx1.1_005565 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M22 compound treatment 0.0034 0.251 0.93 0.003 0.251 0.93 1.3145 1.0 SpOx1.1_005566 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M23 mock treatment 0.0024 0.25 0.93 0.005 0.253 0.94 1.3172 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 M24 mock treatment -0.4919 -0.244 -0.9 -0.4883 -0.24 -0.89 -1.2678 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N01 compound treatment 0.0064 0.254 0.94 0.001 0.249 0.92 1.3172 1.0 SpOx1.1_005567 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N02 compound treatment -0.0206 0.227 0.84 -0.019 0.229 0.85 1.1942 1.0 SpOx1.1_005568 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N03 compound treatment -0.0146 0.233 0.86 -0.02 0.228 0.84 1.2071 0.9999 SpOx1.1_005569 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N04 compound treatment -0.0166 0.231 0.86 -0.017 0.231 0.86 1.21 1.0 SpOx1.1_005570 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N05 compound treatment -0.0146 0.233 0.86 -0.01 0.238 0.88 1.2334 0.9999 SpOx1.1_005571 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N06 compound treatment -0.0136 0.234 0.87 -0.012 0.236 0.87 1.2307 1.0 SpOx1.1_005572 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N07 compound treatment -0.0226 0.225 0.83 -0.022 0.226 0.84 1.1812 1.0 SpOx1.1_005573 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N08 compound treatment -0.0216 0.226 0.84 -0.021 0.227 0.84 1.1862 1.0 SpOx1.1_005574 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N09 compound treatment -0.0336 0.214 0.79 -0.029 0.219 0.81 1.1339 0.9999 SpOx1.1_005575 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N10 compound treatment -0.0056 0.242 0.9 -0.004 0.244 0.9 1.2726 1.0 SpOx1.1_005576 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N11 compound treatment -0.0416 0.206 0.76 -0.037 0.211 0.78 1.0922 0.9999 SpOx1.1_005577 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N12 compound treatment -0.0086 0.239 0.88 -0.013 0.235 0.87 1.2412 1.0 SpOx1.1_005578 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N13 compound treatment -0.0076 0.24 0.89 -0.01 0.238 0.88 1.2517 1.0 SpOx1.1_005579 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N14 compound treatment -0.0286 0.219 0.81 -0.027 0.221 0.82 1.1524 1.0 SpOx1.1_005580 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N15 compound treatment 0.0074 0.255 0.94 0.005 0.253 0.94 1.3302 1.0 SpOx1.1_005581 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N16 compound treatment -0.0016 0.246 0.91 -0.002 0.246 0.91 1.2883 1.0 SpOx1.1_005582 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N17 compound treatment -0.0346 0.213 0.79 -0.028 0.22 0.82 1.1339 0.9999 SpOx1.1_005583 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N18 compound treatment 0.0024 0.25 0.93 -0.003 0.245 0.91 1.2962 1.0 SpOx1.1_005584 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N19 compound treatment -0.0046 0.243 0.9 -0.008 0.24 0.89 1.2649 1.0 SpOx1.1_005585 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N20 compound treatment 0.0054 0.253 0.94 -0.001 0.247 0.92 1.3092 0.9999 SpOx1.1_005586 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N21 compound treatment -0.0276 0.22 0.81 -0.027 0.221 0.82 1.1548 1.0 SpOx1.1_005587 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N22 compound treatment -0.0076 0.24 0.89 -0.007 0.241 0.89 1.2595 1.0 SpOx1.1_005588 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N23 mock treatment 0.0044 0.252 0.93 0.003 0.251 0.93 1.3172 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 N24 mock treatment -0.4899 -0.242 -0.9 -0.4893 -0.241 -0.89 -1.2652 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O01 compound treatment -0.0296 0.218 0.81 -0.033 0.215 0.8 1.134 1.0 SpOx1.1_005589 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O02 compound treatment 0.0034 0.251 0.93 0.008 0.256 0.95 1.3275 0.9999 SpOx1.1_005590 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O03 compound treatment -0.0016 0.246 0.91 0.0 0.248 0.92 1.2937 1.0 SpOx1.1_005591 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O04 compound treatment -0.0046 0.243 0.9 -0.002 0.246 0.91 1.2805 1.0 SpOx1.1_005592 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O05 compound treatment -0.0076 0.24 0.89 -0.007 0.241 0.89 1.2595 1.0 SpOx1.1_005593 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O06 compound treatment -0.0076 0.24 0.89 -0.007 0.241 0.89 1.2595 1.0 SpOx1.1_005594 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O07 compound treatment -0.0076 0.24 0.89 -0.002 0.246 0.91 1.2726 0.9999 SpOx1.1_005595 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O08 compound treatment -0.0106 0.237 0.88 -0.006 0.242 0.9 1.2543 0.9999 SpOx1.1_005596 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O09 compound treatment -0.0316 0.216 0.8 -0.029 0.219 0.81 1.1392 1.0 SpOx1.1_005597 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O10 compound treatment -0.0156 0.232 0.86 -0.019 0.229 0.85 1.2073 1.0 SpOx1.1_005598 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O11 compound treatment -0.0256 0.222 0.82 -0.027 0.221 0.82 1.1601 1.0 SpOx1.1_005599 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O12 compound treatment -0.0246 0.223 0.83 -0.023 0.225 0.83 1.1733 1.0 SpOx1.1_005600 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O13 compound treatment -0.0016 0.246 0.91 0.0 0.248 0.92 1.2936 1.0 SpOx1.1_005601 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O14 compound treatment 0.0024 0.25 0.93 0.002 0.25 0.93 1.3093 1.0 SpOx1.1_005602 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O15 compound treatment -0.0036 0.244 0.9 0.0 0.248 0.92 1.2883 1.0 SpOx1.1_005603 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O16 compound treatment -0.0076 0.24 0.89 -0.006 0.242 0.9 1.2621 1.0 SpOx1.1_005604 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O17 compound treatment -0.0066 0.241 0.89 -0.008 0.24 0.89 1.2595 1.0 SpOx1.1_005605 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O18 compound treatment -0.0206 0.227 0.84 -0.015 0.233 0.86 1.2047 0.9999 SpOx1.1_005606 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O19 compound treatment -0.0056 0.242 0.9 -0.006 0.242 0.9 1.2674 1.0 SpOx1.1_005607 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O20 compound treatment -0.0066 0.241 0.89 -0.009 0.239 0.89 1.2569 1.0 SpOx1.1_005608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O21 compound treatment -0.0126 0.235 0.87 -0.013 0.235 0.87 1.2307 1.0 SpOx1.1_005609 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O22 compound treatment 0.0104 0.258 0.95 0.014 0.262 0.97 1.3616 1.0 SpOx1.1_005610 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O23 mock treatment 0.0034 0.251 0.93 0.002 0.25 0.93 1.312 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 O24 mock treatment -0.4909 -0.243 -0.9 -0.4903 -0.242 -0.9 -1.2704 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P01 compound treatment -0.0286 0.219 0.81 -0.024 0.224 0.83 1.1602 0.9999 SpOx1.1_005611 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P02 compound treatment -0.0056 0.242 0.9 -0.01 0.238 0.88 1.257 1.0 SpOx1.1_005612 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P03 compound treatment -6.0E-4 0.247 0.91 -0.004 0.244 0.9 1.2858 1.0 SpOx1.1_005613 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P04 compound treatment -0.0196 0.228 0.84 -0.017 0.231 0.86 1.2019 1.0 SpOx1.1_005614 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P05 compound treatment -0.0236 0.224 0.83 -0.032 0.216 0.8 1.1522 0.9998 SpOx1.1_005615 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P06 compound treatment -0.0286 0.219 0.81 -0.027 0.221 0.82 1.1522 1.0 SpOx1.1_005616 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P07 compound treatment -0.0226 0.225 0.83 -0.021 0.227 0.84 1.1836 1.0 SpOx1.1_005617 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P08 compound treatment -0.0106 0.237 0.88 -0.011 0.237 0.88 1.2413 1.0 SpOx1.1_005618 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P09 compound treatment -0.0366 0.211 0.78 -0.042 0.206 0.76 1.092 0.9999 SpOx1.1_005619 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P10 compound treatment -0.0356 0.212 0.78 -0.039 0.209 0.77 1.1025 1.0 SpOx1.1_005620 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P11 compound treatment -0.0396 0.208 0.77 -0.039 0.209 0.77 1.092 1.0 SpOx1.1_005621 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P12 compound treatment -0.0226 0.225 0.83 -0.022 0.226 0.84 1.1812 1.0 SpOx1.1_005622 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P13 compound treatment -0.0416 0.206 0.76 -0.037 0.211 0.78 1.092 0.9999 SpOx1.1_005623 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P14 compound treatment -0.0236 0.224 0.83 -0.02 0.228 0.84 1.1838 1.0 SpOx1.1_005624 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P15 compound treatment -0.0186 0.229 0.85 -0.022 0.226 0.84 1.1916 1.0 SpOx1.1_005625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P16 compound treatment -0.0216 0.226 0.84 -0.018 0.23 0.85 1.1941 1.0 SpOx1.1_005626 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P17 compound treatment -0.0286 0.219 0.81 -0.032 0.216 0.8 1.1391 1.0 SpOx1.1_005627 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P18 compound treatment -0.0066 0.241 0.89 -0.009 0.239 0.89 1.2569 1.0 SpOx1.1_005628 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P19 compound treatment -0.0096 0.238 0.88 -0.013 0.235 0.87 1.2387 1.0 SpOx1.1_005629 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P20 compound treatment -0.0096 0.238 0.88 -0.011 0.237 0.88 1.2439 1.0 SpOx1.1_005630 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P21 compound treatment 4.0E-4 0.248 0.92 0.003 0.251 0.93 1.3066 1.0 SpOx1.1_005631 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P22 compound treatment -0.0056 0.242 0.9 -0.007 0.241 0.89 1.2649 1.0 SpOx1.1_005632 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P23 mock treatment -6.0E-4 0.247 0.91 0.0 0.248 0.92 1.2962 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1294 P24 mock treatment -0.4899 -0.242 -0.9 -0.4923 -0.244 -0.91 -1.2731 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A01 compound treatment -0.0979 0.149 0.55 -0.0813 0.165 0.61 0.82 0.9987 SpOx1.1_005633 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A02 compound treatment -0.0899 0.157 0.58 -0.0763 0.17 0.63 0.854 0.9992 SpOx1.1_005634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A03 compound treatment -0.0814 0.165 0.61 -0.0663 0.18 0.67 0.9025 0.9991 SpOx1.1_005635 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A04 compound treatment -0.0929 0.154 0.57 -0.0783 0.168 0.62 0.8409 0.999 SpOx1.1_005636 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A05 compound treatment -0.0784 0.168 0.62 -0.0743 0.172 0.64 0.8893 0.9999 SpOx1.1_005637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A06 compound treatment -0.0949 0.152 0.56 -0.0792 0.167 0.62 0.8333 0.9989 SpOx1.1_005638 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A07 compound treatment -0.0714 0.175 0.65 -0.0603 0.186 0.69 0.9443 0.9996 SpOx1.1_005639 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A08 compound treatment -0.0874 0.159 0.59 -0.0763 0.17 0.63 0.8606 0.9995 SpOx1.1_005640 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A09 compound treatment -0.1039 0.143 0.53 -0.0902 0.156 0.58 0.7809 0.999 SpOx1.1_005641 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A10 compound treatment -0.0889 0.158 0.58 -0.0753 0.171 0.63 0.8592 0.9992 SpOx1.1_005642 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A11 compound treatment -0.0904 0.156 0.58 -0.0733 0.173 0.64 0.8606 0.9987 SpOx1.1_005643 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A12 compound treatment -0.0844 0.162 0.6 -0.0663 0.18 0.67 0.8946 0.9987 SpOx1.1_005644 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A13 compound treatment -0.0939 0.153 0.56 -0.0753 0.171 0.63 0.8461 0.9984 SpOx1.1_005645 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A14 compound treatment -0.1069 0.14 0.52 -0.0842 0.162 0.6 0.7889 0.9973 SpOx1.1_005646 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A15 compound treatment -0.0834 0.163 0.6 -0.0683 0.178 0.66 0.8919 0.9991 SpOx1.1_005647 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A16 compound treatment -0.0834 0.163 0.6 -0.0723 0.174 0.64 0.8815 0.9995 SpOx1.1_005648 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A17 compound treatment -0.0909 0.156 0.58 -0.0753 0.171 0.63 0.854 0.9989 SpOx1.1_005649 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A18 compound treatment -0.0794 0.167 0.62 -0.0683 0.178 0.66 0.9024 0.9995 SpOx1.1_005650 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A19 compound treatment -0.0869 0.16 0.59 -0.0723 0.174 0.64 0.8723 0.9991 SpOx1.1_005651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A20 compound treatment -0.0834 0.163 0.6 -0.0763 0.17 0.63 0.871 0.9998 SpOx1.1_005652 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A21 compound treatment -0.1119 0.135 0.5 -0.0992 0.147 0.54 0.7365 0.9991 SpOx1.1_005653 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A22 compound treatment -0.0899 0.157 0.58 -0.0763 0.17 0.63 0.854 0.9992 SpOx1.1_005654 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A23 mock treatment -0.0774 0.169 0.63 -0.0643 0.182 0.67 0.9181 0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 A24 mock treatment -0.4845 -0.238 -0.88 -0.4881 -0.242 -0.9 -1.2567 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B01 compound treatment -0.0194 0.227 0.84 -0.0063 0.24 0.89 1.2219 0.9996 SpOx1.1_005655 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B02 compound treatment -0.0074 0.239 0.88 0.0047 0.251 0.93 1.282 0.9997 2142147 SpOx1.1_005656 COC(=O)[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCN(C)Cc8ccccc8)ccc17)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B03 compound treatment 0.0026 0.249 0.92 0.0097 0.256 0.95 1.3212 0.9999 SpOx1.1_005657 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B04 compound treatment 0.0066 0.253 0.94 0.0167 0.263 0.97 1.35 0.9998 SpOx1.1_005658 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B05 compound treatment 0.0036 0.25 0.93 0.0177 0.264 0.98 1.3448 0.9996 SpOx1.1_005659 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B06 compound treatment -0.0174 0.229 0.85 -0.0023 0.244 0.9 1.2376 0.9995 SpOx1.1_005660 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B07 compound treatment -0.0064 0.24 0.89 0.0077 0.254 0.94 1.2924 0.9996 SpOx1.1_005661 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B08 compound treatment 0.0026 0.249 0.92 0.0207 0.267 0.99 1.35 0.9994 SpOx1.1_005662 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B09 compound treatment -0.0084 0.238 0.88 0.0097 0.256 0.95 1.2923 0.9993 SpOx1.1_005663 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B10 compound treatment -0.0074 0.239 0.88 0.0087 0.255 0.94 1.2924 0.9995 SpOx1.1_005664 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B11 compound treatment -0.0304 0.216 0.8 -0.0123 0.234 0.87 1.1772 0.9992 SpOx1.1_005665 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B12 compound treatment -0.0164 0.23 0.85 0.0037 0.25 0.92 1.2557 0.9991 SpOx1.1_005666 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B13 compound treatment -0.0104 0.236 0.87 0.0057 0.252 0.93 1.2766 0.9995 SpOx1.1_005667 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B14 compound treatment -0.0014 0.245 0.91 0.0137 0.26 0.96 1.3212 0.9996 SpOx1.1_005668 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B15 compound treatment -0.0104 0.236 0.87 -0.0043 0.242 0.89 1.2505 0.9999 SpOx1.1_005669 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B16 compound treatment -4.0E-4 0.246 0.91 0.0057 0.252 0.93 1.3028 0.9999 SpOx1.1_005670 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B17 compound treatment 6.0E-4 0.247 0.91 0.0147 0.261 0.97 1.329 0.9996 SpOx1.1_005671 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B18 compound treatment -0.0114 0.235 0.87 0.0087 0.255 0.94 1.2819 0.9992 SpOx1.1_005672 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B19 compound treatment -0.0104 0.236 0.87 0.0087 0.255 0.94 1.2845 0.9993 SpOx1.1_005673 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B20 compound treatment -0.0124 0.234 0.87 -3.0E-4 0.246 0.91 1.2556 0.9997 SpOx1.1_005674 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B21 compound treatment 0.0046 0.251 0.93 0.0147 0.261 0.97 1.3395 0.9998 SpOx1.1_005675 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B22 compound treatment -0.0074 0.239 0.88 0.0057 0.252 0.93 1.2846 0.9997 SpOx1.1_005676 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B23 mock treatment 0.0066 0.253 0.94 0.0177 0.264 0.98 1.3526 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 B24 mock treatment -0.4865 -0.24 -0.89 -0.4871 -0.241 -0.89 -1.2594 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C01 compound treatment -0.0174 0.229 0.85 -0.0033 0.243 0.9 1.2349 0.9996 SpOx1.1_005677 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C02 compound treatment -0.0204 0.226 0.84 -0.0153 0.231 0.85 1.1955 0.9999 SpOx1.1_005678 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C03 compound treatment -0.0184 0.228 0.84 -0.0073 0.239 0.88 1.2218 0.9997 SpOx1.1_005679 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C04 compound treatment -0.0074 0.239 0.88 0.0047 0.251 0.93 1.282 0.9997 SpOx1.1_005680 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C05 compound treatment -0.0024 0.244 0.9 0.0117 0.258 0.95 1.3134 0.9996 SpOx1.1_005681 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C06 compound treatment -0.0174 0.229 0.85 -0.0063 0.24 0.89 1.227 0.9997 SpOx1.1_005682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C07 compound treatment -0.0194 0.227 0.84 -0.0073 0.239 0.88 1.2192 0.9997 SpOx1.1_005683 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C08 compound treatment -0.0094 0.237 0.88 0.0027 0.249 0.92 1.2714 0.9997 SpOx1.1_005684 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C09 compound treatment -0.0134 0.233 0.86 0.0027 0.249 0.92 1.2609 0.9995 SpOx1.1_005685 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C10 compound treatment -0.0224 0.224 0.83 -0.0153 0.231 0.85 1.1904 0.9999 SpOx1.1_005686 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C11 compound treatment -0.0194 0.227 0.84 -0.0063 0.24 0.89 1.2219 0.9996 SpOx1.1_005687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C12 compound treatment -0.0154 0.231 0.85 -0.0023 0.244 0.9 1.2426 0.9996 SpOx1.1_005688 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C13 compound treatment -0.0274 0.219 0.81 -0.0113 0.235 0.87 1.1877 0.9994 SpOx1.1_005689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C14 compound treatment -0.0294 0.217 0.8 -0.0203 0.226 0.84 1.159 0.9998 SpOx1.1_005690 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C15 compound treatment -0.0274 0.219 0.81 -0.0183 0.228 0.84 1.1694 0.9998 SpOx1.1_005691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C16 compound treatment -0.0104 0.236 0.87 -0.1461 0.0997 0.37 0.8789 0.9267 SpOx1.1_005692 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C17 compound treatment -0.0104 0.236 0.87 0.0027 0.249 0.92 1.2688 0.9997 SpOx1.1_005693 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C18 compound treatment -0.0124 0.234 0.87 -0.0053 0.241 0.89 1.2426 0.9999 SpOx1.1_005694 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C19 compound treatment -0.0134 0.233 0.86 -0.0053 0.241 0.89 1.2402 0.9999 SpOx1.1_005695 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C20 compound treatment -0.0274 0.219 0.81 -0.0173 0.229 0.85 1.172 0.9998 SpOx1.1_005696 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C21 compound treatment -0.0094 0.237 0.88 -0.0053 0.241 0.89 1.2505 1.0 SpOx1.1_005697 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C22 compound treatment -0.0204 0.226 0.84 -0.0213 0.225 0.83 1.1799 1.0 SpOx1.1_005698 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C23 mock treatment -0.0204 0.226 0.84 -0.0093 0.237 0.88 1.2113 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 C24 mock treatment -0.4865 -0.24 -0.89 -0.4871 -0.241 -0.89 -1.2594 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D01 compound treatment -0.0184 0.228 0.84 -0.0033 0.243 0.9 1.2323 0.9995 SpOx1.1_005699 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D02 compound treatment -0.0224 0.224 0.83 -0.0083 0.238 0.88 1.2088 0.9996 SpOx1.1_005700 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D03 compound treatment -0.0214 0.225 0.83 -0.0063 0.24 0.89 1.2166 0.9995 SpOx1.1_005701 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D04 compound treatment -0.0364 0.21 0.78 -0.0203 0.226 0.84 1.1407 0.9993 SpOx1.1_005702 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D05 compound treatment -0.0234 0.223 0.83 -0.0093 0.237 0.88 1.2034 0.9995 SpOx1.1_005703 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D06 compound treatment -0.0224 0.224 0.83 -0.0023 0.244 0.9 1.2243 0.9991 SpOx1.1_005704 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D07 compound treatment -0.0134 0.233 0.86 -0.0073 0.239 0.88 1.2348 0.9999 SpOx1.1_005705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D08 compound treatment -0.0214 0.225 0.83 -0.0113 0.235 0.87 1.2034 0.9998 SpOx1.1_005706 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D09 compound treatment -0.0204 0.226 0.84 -0.0093 0.237 0.88 1.2112 0.9997 SpOx1.1_005707 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D10 compound treatment -0.0204 0.226 0.84 -0.0163 0.23 0.85 1.193 1.0 SpOx1.1_005708 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D11 compound treatment -0.0044 0.242 0.9 0.0057 0.252 0.93 1.2924 0.9998 SpOx1.1_005709 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D12 compound treatment -0.0204 0.226 0.84 -0.0053 0.241 0.89 1.2217 0.9995 SpOx1.1_005710 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D13 compound treatment -0.0164 0.23 0.85 -0.0023 0.244 0.9 1.24 0.9996 SpOx1.1_005711 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D14 compound treatment -0.0214 0.225 0.83 -0.0123 0.234 0.87 1.2009 0.9998 SpOx1.1_005712 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D15 compound treatment -0.0344 0.212 0.78 -0.0213 0.225 0.83 1.1432 0.9996 SpOx1.1_005713 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D16 compound treatment -0.0154 0.231 0.85 -0.0073 0.239 0.88 1.2295 0.9999 SpOx1.1_005714 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D17 compound treatment -0.0224 0.224 0.83 -0.0143 0.232 0.86 1.1929 0.9999 SpOx1.1_005715 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D18 compound treatment -0.0224 0.224 0.83 -0.0053 0.241 0.89 1.2164 0.9993 SpOx1.1_005716 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D19 compound treatment -0.0264 0.22 0.81 -0.0183 0.228 0.84 1.172 0.9998 SpOx1.1_005717 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D20 compound treatment -0.0184 0.228 0.84 -0.0093 0.237 0.88 1.2164 0.9998 SpOx1.1_005718 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D21 compound treatment -0.0254 0.221 0.82 -0.0173 0.229 0.85 1.1773 0.9999 SpOx1.1_005719 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D22 compound treatment -0.0014 0.245 0.91 0.0067 0.253 0.94 1.3028 0.9999 SpOx1.1_005720 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D23 mock treatment -0.0124 0.234 0.87 -0.0063 0.24 0.89 1.2401 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 D24 mock treatment -0.4875 -0.241 -0.89 -0.4861 -0.24 -0.89 -1.2593 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E01 compound treatment -0.0254 0.221 0.82 -0.0033 0.243 0.9 1.2139 0.9989 SpOx1.1_005721 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E02 compound treatment -0.0024 0.244 0.9 0.0107 0.257 0.95 1.3107 0.9997 SpOx1.1_005722 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E03 compound treatment -0.0054 0.241 0.89 7.0E-4 0.247 0.91 1.2767 0.9999 SpOx1.1_005723 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E04 compound treatment -0.0114 0.235 0.87 0.0017 0.248 0.92 1.2637 0.9996 SpOx1.1_005724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E05 compound treatment -0.0104 0.236 0.87 0.0067 0.253 0.94 1.2793 0.9994 SpOx1.1_005725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E06 compound treatment -0.0024 0.244 0.9 0.0107 0.257 0.95 1.3107 0.9997 SpOx1.1_005726 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E07 compound treatment -0.0044 0.242 0.9 0.0077 0.254 0.94 1.2976 0.9997 SpOx1.1_005727 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E08 compound treatment 0.0066 0.253 0.94 0.0117 0.258 0.95 1.3368 1.0 SpOx1.1_005728 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E09 compound treatment -0.0024 0.244 0.9 0.0127 0.259 0.96 1.3159 0.9996 SpOx1.1_005729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E10 compound treatment -0.0134 0.233 0.86 -0.0103 0.236 0.87 1.2269 1.0 SpOx1.1_005730 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E11 compound treatment -0.0334 0.213 0.79 -0.0163 0.23 0.85 1.1589 0.9993 SpOx1.1_005731 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E12 compound treatment -0.0154 0.231 0.85 -0.0023 0.244 0.9 1.2426 0.9996 SpOx1.1_005732 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E13 compound treatment -0.0074 0.239 0.88 0.0067 0.253 0.94 1.2871 0.9996 SpOx1.1_005733 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E14 compound treatment -0.0114 0.235 0.87 -0.0053 0.241 0.89 1.2453 0.9999 SpOx1.1_005734 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E15 compound treatment 0.0136 0.26 0.96 0.0167 0.263 0.97 1.3682 1.0 SpOx1.1_005735 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E16 compound treatment -0.0014 0.245 0.91 0.0037 0.25 0.92 1.295 1.0 SpOx1.1_005736 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E17 compound treatment -0.0254 0.221 0.82 -0.0133 0.233 0.86 1.1877 0.9997 SpOx1.1_005737 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E18 compound treatment 6.0E-4 0.247 0.91 0.0107 0.257 0.95 1.3185 0.9998 SpOx1.1_005738 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E19 compound treatment -0.0164 0.23 0.85 -0.0143 0.232 0.86 1.2086 1.0 SpOx1.1_005739 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E20 compound treatment -0.0104 0.236 0.87 0.0027 0.249 0.92 1.2688 0.9997 SpOx1.1_005740 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E21 compound treatment -0.0064 0.24 0.89 0.0057 0.252 0.93 1.2871 0.9997 SpOx1.1_005741 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E22 compound treatment -0.0044 0.242 0.9 -0.0013 0.245 0.91 1.274 1.0 SpOx1.1_005742 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E23 mock treatment -0.0054 0.241 0.89 0.0047 0.251 0.93 1.2872 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 E24 mock treatment -0.4865 -0.24 -0.89 -0.4861 -0.24 -0.89 -1.2567 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F01 compound treatment -0.0184 0.228 0.84 -0.0063 0.24 0.89 1.2245 0.9997 SpOx1.1_005743 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F02 compound treatment -0.0074 0.239 0.88 0.0047 0.251 0.93 1.2818 0.9997 SpOx1.1_005744 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F03 compound treatment -0.0114 0.235 0.87 -0.0053 0.241 0.89 1.2452 0.9999 SpOx1.1_005745 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F04 compound treatment -0.0174 0.229 0.85 -0.0053 0.241 0.89 1.2296 0.9997 SpOx1.1_005746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F05 compound treatment -0.0054 0.241 0.89 0.0107 0.257 0.95 1.3029 0.9995 SpOx1.1_005747 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F06 compound treatment -4.0E-4 0.246 0.91 0.0107 0.257 0.95 1.3159 0.9998 SpOx1.1_005748 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F07 compound treatment -0.0104 0.236 0.87 0.0017 0.248 0.92 1.2661 0.9997 SpOx1.1_005749 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F08 compound treatment -0.0014 0.245 0.91 0.0097 0.256 0.95 1.3107 0.9998 SpOx1.1_005750 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F09 compound treatment -0.0224 0.224 0.83 -0.0133 0.233 0.86 1.1956 0.9998 SpOx1.1_005751 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F10 compound treatment 0.0026 0.249 0.92 0.0087 0.255 0.94 1.3185 0.9999 SpOx1.1_005752 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F11 compound treatment -0.0224 0.224 0.83 -0.0043 0.242 0.9 1.2191 0.9993 SpOx1.1_005753 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F12 compound treatment -0.0124 0.234 0.87 -0.0043 0.242 0.89 1.2452 0.9999 SpOx1.1_005754 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F13 compound treatment -0.0284 0.218 0.81 -0.0203 0.226 0.84 1.1615 0.9998 SpOx1.1_005755 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F14 compound treatment -0.0074 0.239 0.88 0.0017 0.248 0.92 1.274 0.9998 SpOx1.1_005756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F15 compound treatment -0.0124 0.234 0.87 -0.0043 0.242 0.89 1.2452 0.9999 SpOx1.1_005757 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F16 compound treatment 0.0036 0.25 0.93 0.0067 0.253 0.94 1.3159 1.0 SpOx1.1_005758 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F17 compound treatment -0.0054 0.241 0.89 -0.0143 0.232 0.86 1.2373 0.9998 SpOx1.1_005759 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F18 compound treatment -0.0024 0.244 0.9 7.0E-4 0.247 0.91 1.2845 1.0 SpOx1.1_005760 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F19 compound treatment 0.0036 0.25 0.93 0.0097 0.256 0.95 1.3238 0.9999 SpOx1.1_005761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F20 compound treatment -0.0564 0.19 0.7 -0.0483 0.198 0.73 1.0148 0.9998 SpOx1.1_005762 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F21 compound treatment -0.0074 0.239 0.88 0.0037 0.25 0.92 1.2792 0.9998 SpOx1.1_005763 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F22 compound treatment 6.0E-4 0.247 0.91 7.0E-4 0.247 0.91 1.2923 1.0 SpOx1.1_005764 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F23 mock treatment 0.0086 0.255 0.94 0.0157 0.262 0.97 1.3526 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 F24 mock treatment -0.4865 -0.24 -0.89 -0.4861 -0.24 -0.89 -1.2567 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G01 compound treatment -0.0034 0.243 0.9 0.0077 0.254 0.94 1.3003 0.9998 SpOx1.1_005765 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G02 compound treatment -0.0074 0.239 0.88 7.0E-4 0.247 0.91 1.2713 0.9999 SpOx1.1_005766 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G03 compound treatment -0.0394 0.207 0.77 -0.0183 0.228 0.84 1.138 0.9989 SpOx1.1_005767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G04 compound treatment -0.0184 0.228 0.84 -0.0033 0.243 0.9 1.2322 0.9995 SpOx1.1_005768 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G05 compound treatment -0.0324 0.214 0.79 -0.0063 0.24 0.89 1.1877 0.9984 SpOx1.1_005769 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G06 compound treatment -0.0244 0.222 0.82 -0.0133 0.233 0.86 1.1903 0.9997 SpOx1.1_005770 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G07 compound treatment -0.0064 0.24 0.89 0.0057 0.252 0.93 1.2871 0.9997 SpOx1.1_005771 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G08 compound treatment -0.0204 0.226 0.84 -0.0143 0.232 0.86 1.1981 0.9999 SpOx1.1_005772 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G09 compound treatment -0.0214 0.225 0.83 -0.0113 0.235 0.87 1.2034 0.9998 SpOx1.1_005773 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G10 compound treatment -0.0154 0.231 0.85 -0.0013 0.245 0.91 1.2453 0.9996 SpOx1.1_005774 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G11 compound treatment -0.0154 0.231 0.85 -0.0053 0.241 0.89 1.2349 0.9998 SpOx1.1_005775 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G12 compound treatment -0.0074 0.239 0.88 -0.0053 0.241 0.89 1.2558 1.0 SpOx1.1_005776 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G13 compound treatment -0.0184 0.228 0.84 -0.0033 0.243 0.9 1.2323 0.9995 SpOx1.1_005777 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G14 compound treatment -0.0304 0.216 0.8 -0.0103 0.236 0.87 1.1825 0.999 SpOx1.1_005778 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G15 compound treatment -0.0144 0.232 0.86 -0.0093 0.237 0.88 1.2269 0.9999 SpOx1.1_005779 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G16 compound treatment -0.0394 0.207 0.77 -0.0263 0.22 0.81 1.117 0.9996 SpOx1.1_005780 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G17 compound treatment -0.0204 0.226 0.84 -0.0133 0.233 0.86 1.2007 0.9999 SpOx1.1_005781 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G18 compound treatment -0.0174 0.229 0.85 -0.0133 0.233 0.86 1.2085 1.0 SpOx1.1_005782 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G19 compound treatment -0.0204 0.226 0.84 -0.0143 0.232 0.86 1.1981 0.9999 SpOx1.1_005783 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G20 compound treatment -0.0334 0.213 0.79 -0.0313 0.215 0.79 1.1197 1.0 2144923 SpOx1.1_005784 COC(=O)[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G21 compound treatment -0.0184 0.228 0.84 -0.0113 0.235 0.87 1.2112 0.9999 SpOx1.1_005785 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G22 compound treatment -0.0204 0.226 0.84 -0.0113 0.235 0.87 1.2061 0.9998 SpOx1.1_005786 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G23 mock treatment -0.0164 0.23 0.85 -0.0103 0.236 0.87 1.2191 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 G24 mock treatment -0.4865 -0.24 -0.89 -0.4861 -0.24 -0.89 -1.2567 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H01 compound treatment -0.0174 0.229 0.85 -0.0053 0.241 0.89 1.2296 0.9997 SpOx1.1_005787 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H02 compound treatment -0.0224 0.224 0.83 -0.0183 0.228 0.84 1.1825 1.0 SpOx1.1_005788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H03 compound treatment -0.0124 0.234 0.87 -0.0053 0.241 0.89 1.2426 0.9999 SpOx1.1_005789 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H04 compound treatment -0.0154 0.231 0.85 -0.0053 0.241 0.89 1.2348 0.9998 SpOx1.1_005790 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H05 compound treatment -0.0204 0.226 0.84 -0.0083 0.238 0.88 1.2138 0.9997 SpOx1.1_005791 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H06 compound treatment -0.0164 0.23 0.85 -0.0073 0.239 0.88 1.2269 0.9998 SpOx1.1_005792 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H07 compound treatment -0.0204 0.226 0.84 -0.0093 0.237 0.88 1.2112 0.9997 SpOx1.1_005793 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H08 compound treatment -0.0164 0.23 0.85 -0.0463 0.2 0.74 1.1249 0.9975 SpOx1.1_005794 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H09 compound treatment -0.0094 0.237 0.88 0.0027 0.249 0.92 1.2715 0.9997 SpOx1.1_005795 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H10 compound treatment -0.0244 0.222 0.82 -0.0173 0.229 0.85 1.1798 0.9999 SpOx1.1_005796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H11 compound treatment -0.0204 0.226 0.84 -0.0093 0.237 0.88 1.2112 0.9997 SpOx1.1_005797 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H12 compound treatment -0.0204 0.226 0.84 -0.0063 0.24 0.89 1.2191 0.9996 SpOx1.1_005798 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H13 compound treatment -0.0094 0.237 0.88 -0.0013 0.245 0.91 1.261 0.9999 SpOx1.1_005799 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H14 compound treatment -0.0024 0.244 0.9 -0.0013 0.245 0.91 1.2793 1.0 SpOx1.1_005800 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H15 compound treatment -0.0164 0.23 0.85 -0.0033 0.243 0.9 1.2374 0.9996 SpOx1.1_005801 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H16 compound treatment -0.0094 0.237 0.88 -0.0043 0.242 0.89 1.253 0.9999 SpOx1.1_005802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H17 compound treatment -0.0084 0.238 0.88 -0.0093 0.237 0.88 1.2426 1.0 SpOx1.1_005803 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H18 compound treatment -0.0264 0.22 0.81 -0.0253 0.221 0.82 1.1536 1.0 SpOx1.1_005804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H19 compound treatment -0.0174 0.229 0.85 -0.0143 0.232 0.86 1.206 1.0 SpOx1.1_005805 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H20 compound treatment -0.0214 0.225 0.83 -0.0293 0.217 0.8 1.1562 0.9998 SpOx1.1_005806 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H21 compound treatment -0.0304 0.216 0.8 -0.0223 0.224 0.83 1.1511 0.9998 SpOx1.1_005807 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H22 compound treatment -0.0134 0.233 0.86 -0.0053 0.241 0.89 1.2401 0.9999 SpOx1.1_005808 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H23 mock treatment -0.0164 0.23 0.85 -0.0123 0.234 0.87 1.2139 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 H24 mock treatment -0.4855 -0.239 -0.88 -0.4881 -0.242 -0.9 -1.2594 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I01 compound treatment -0.0014 0.245 0.91 0.0077 0.254 0.94 1.3055 0.9998 SpOx1.1_005809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I02 compound treatment -0.0124 0.234 0.87 -0.0073 0.239 0.88 1.2374 0.9999 SpOx1.1_005810 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I03 compound treatment 0.0036 0.25 0.93 0.0107 0.257 0.95 1.3265 0.9999 SpOx1.1_005811 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I04 compound treatment -0.0324 0.214 0.79 -0.0333 0.213 0.79 1.117 1.0 SpOx1.1_005812 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I05 compound treatment -0.0314 0.215 0.8 -0.0243 0.222 0.82 1.1432 0.9999 SpOx1.1_005813 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I06 compound treatment -0.0174 0.229 0.85 -0.0073 0.239 0.88 1.2244 0.9998 SpOx1.1_005814 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I07 compound treatment -0.0484 0.198 0.73 -0.0373 0.209 0.77 1.0647 0.9996 SpOx1.1_005815 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I08 compound treatment -0.0324 0.214 0.79 -0.0253 0.221 0.82 1.1379 0.9999 SpOx1.1_005816 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I09 compound treatment -0.0024 0.244 0.9 0.0077 0.254 0.94 1.3028 0.9998 SpOx1.1_005817 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I10 compound treatment -0.0124 0.234 0.87 -0.0033 0.243 0.9 1.2479 0.9998 SpOx1.1_005818 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I11 compound treatment -0.0134 0.233 0.86 -0.0123 0.234 0.87 1.2217 1.0 SpOx1.1_005819 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I12 compound treatment -0.0514 0.195 0.72 -0.0463 0.2 0.74 1.0332 0.9999 SpOx1.1_005820 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I13 compound treatment -0.0144 0.232 0.86 -0.0093 0.237 0.88 1.2269 0.9999 SpOx1.1_005821 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I14 compound treatment -0.0204 0.226 0.84 -0.0103 0.236 0.87 1.2086 0.9998 SpOx1.1_005822 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I15 compound treatment -0.0414 0.205 0.76 -0.0173 0.229 0.85 1.1353 0.9985 SpOx1.1_005823 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I16 compound treatment -0.0384 0.208 0.77 -0.0203 0.226 0.84 1.1353 0.9992 SpOx1.1_005824 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I17 compound treatment -4.0E-4 0.246 0.91 -0.0013 0.245 0.91 1.2845 1.0 SpOx1.1_005825 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I18 compound treatment -0.0264 0.22 0.81 -0.0143 0.232 0.86 1.1824 0.9997 SpOx1.1_005826 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I19 compound treatment -0.0224 0.224 0.83 -0.0183 0.228 0.84 1.1824 1.0 SpOx1.1_005827 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I20 compound treatment -0.0194 0.227 0.84 -0.0143 0.232 0.86 1.2007 0.9999 SpOx1.1_005828 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I21 compound treatment -0.0094 0.237 0.88 -0.0073 0.239 0.88 1.2452 1.0 SpOx1.1_005829 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I22 compound treatment -0.0384 0.208 0.77 -0.0493 0.197 0.73 1.0594 0.9996 SpOx1.1_005830 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I23 mock treatment 6.0E-4 0.247 0.91 0.0027 0.249 0.92 1.2976 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 I24 mock treatment -0.4895 -0.243 -0.9 -0.4871 -0.241 -0.89 -1.2672 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J01 compound treatment -0.0174 0.229 0.85 -0.0123 0.234 0.87 1.2114 0.9999 SpOx1.1_005831 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J02 compound treatment -0.0024 0.244 0.9 -0.0343 0.212 0.78 1.1928 0.9975 SpOx1.1_005832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J03 compound treatment -0.0154 0.231 0.86 -0.0073 0.239 0.88 1.2297 0.9999 SpOx1.1_005833 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J04 compound treatment -0.0074 0.239 0.88 -3.0E-4 0.246 0.91 1.2689 0.9999 SpOx1.1_005834 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J05 compound treatment -0.0324 0.214 0.79 -0.0203 0.226 0.84 1.151 0.9996 SpOx1.1_005835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J06 compound treatment -0.0174 0.229 0.85 -0.0093 0.237 0.88 1.2191 0.9999 SpOx1.1_005836 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J07 compound treatment -0.0194 0.227 0.84 -0.0113 0.235 0.87 1.2086 0.9999 SpOx1.1_005837 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J08 compound treatment -0.0194 0.227 0.84 -0.0143 0.232 0.86 1.2007 0.9999 SpOx1.1_005838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J09 compound treatment -0.0134 0.233 0.86 -0.0053 0.241 0.89 1.2401 0.9999 SpOx1.1_005839 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J10 compound treatment -0.0244 0.222 0.82 -0.0173 0.229 0.85 1.1799 0.9999 SpOx1.1_005840 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J11 compound treatment -0.0104 0.236 0.87 -0.0063 0.24 0.89 1.2453 1.0 SpOx1.1_005841 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J12 compound treatment -0.0174 0.229 0.85 -0.0093 0.237 0.88 1.2192 0.9999 SpOx1.1_005842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J13 compound treatment -0.0474 0.199 0.74 -0.0323 0.214 0.79 1.0804 0.9994 SpOx1.1_005843 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J14 compound treatment -0.0234 0.223 0.83 -0.0163 0.23 0.85 1.1851 0.9999 SpOx1.1_005844 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J15 compound treatment -0.0104 0.236 0.87 -0.0093 0.237 0.88 1.2375 1.0 SpOx1.1_005845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J16 compound treatment -0.0214 0.225 0.83 -0.0143 0.232 0.86 1.1957 0.9999 SpOx1.1_005846 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J17 compound treatment -0.0044 0.242 0.9 -0.0023 0.244 0.9 1.2715 1.0 SpOx1.1_005847 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J18 compound treatment -0.0164 0.23 0.85 -0.0163 0.23 0.85 1.2035 1.0 SpOx1.1_005848 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J19 compound treatment 0.0016 0.248 0.92 -0.0043 0.242 0.89 1.2819 0.9999 SpOx1.1_005849 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J20 compound treatment -0.0084 0.238 0.88 -0.0083 0.238 0.88 1.2452 1.0 SpOx1.1_005850 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J21 compound treatment -0.0104 0.236 0.87 -0.0033 0.243 0.9 1.253 0.9999 SpOx1.1_005851 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J22 compound treatment -0.0014 0.245 0.91 0.0017 0.248 0.92 1.2897 1.0 SpOx1.1_005852 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J23 mock treatment -0.0114 0.235 0.87 -0.0073 0.239 0.88 1.2401 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 J24 mock treatment -0.4885 -0.242 -0.89 -0.4871 -0.241 -0.89 -1.2646 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K01 compound treatment -0.0144 0.232 0.86 -3.0E-4 0.246 0.91 1.2504 0.9996 SpOx1.1_005853 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K02 compound treatment -0.0174 0.229 0.85 -0.0083 0.238 0.88 1.2218 0.9998 SpOx1.1_005854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K03 compound treatment -0.0154 0.231 0.85 -0.0113 0.235 0.87 1.2191 1.0 SpOx1.1_005855 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K04 compound treatment -0.0144 0.232 0.86 -0.0093 0.237 0.88 1.2269 0.9999 SpOx1.1_005856 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K05 compound treatment -0.0204 0.226 0.84 -0.0153 0.231 0.85 1.1955 0.9999 SpOx1.1_005857 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K06 compound treatment -0.0014 0.245 0.91 0.0057 0.252 0.93 1.3002 0.9999 SpOx1.1_005858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K07 compound treatment -0.0374 0.209 0.77 -0.0333 0.213 0.79 1.104 1.0 SpOx1.1_005859 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K08 compound treatment -0.0174 0.229 0.85 -0.0123 0.234 0.87 1.2113 0.9999 SpOx1.1_005860 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K09 compound treatment -0.0264 0.22 0.81 -0.0103 0.236 0.87 1.1931 0.9994 SpOx1.1_005861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K10 compound treatment -0.0114 0.235 0.87 -0.0053 0.241 0.89 1.2452 0.9999 SpOx1.1_005862 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K11 compound treatment -0.0154 0.231 0.86 -0.0063 0.24 0.89 1.2323 0.9998 SpOx1.1_005863 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K12 compound treatment -0.0274 0.219 0.81 -0.0063 0.24 0.89 1.2008 0.999 SpOx1.1_005864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K13 compound treatment -0.0464 0.2 0.74 -0.0363 0.21 0.78 1.0725 0.9997 SpOx1.1_005865 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K14 compound treatment -0.0024 0.244 0.9 -0.0033 0.243 0.9 1.2741 1.0 SpOx1.1_005866 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K15 compound treatment -0.0024 0.244 0.9 -0.0073 0.239 0.88 1.2636 0.9999 SpOx1.1_005867 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K16 compound treatment -0.0164 0.23 0.85 -0.0153 0.231 0.85 1.206 1.0 SpOx1.1_005868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K17 compound treatment -0.0284 0.218 0.81 -0.0143 0.232 0.86 1.1773 0.9995 SpOx1.1_005869 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K18 compound treatment -0.0194 0.227 0.84 -0.0153 0.231 0.85 1.198 1.0 SpOx1.1_005870 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K19 compound treatment -0.0184 0.228 0.84 -0.0223 0.224 0.83 1.1824 1.0 SpOx1.1_005871 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K20 compound treatment -0.0254 0.221 0.82 -0.0203 0.226 0.84 1.1694 0.9999 SpOx1.1_005872 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K21 compound treatment -0.0154 0.231 0.86 -0.0153 0.231 0.85 1.2086 1.0 SpOx1.1_005873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K22 compound treatment -0.0254 0.221 0.82 -0.0323 0.214 0.79 1.1379 0.9999 SpOx1.1_005874 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K23 mock treatment -0.0114 0.235 0.87 -0.0083 0.238 0.88 1.2375 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 K24 mock treatment -0.4865 -0.24 -0.89 -0.4871 -0.241 -0.89 -1.2594 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L01 compound treatment -0.0174 0.229 0.85 -0.0063 0.24 0.89 1.227 0.9997 SpOx1.1_005875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L02 compound treatment -4.0E-4 0.246 0.91 0.0187 0.265 0.98 1.3369 0.9993 SpOx1.1_005876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L03 compound treatment -0.0074 0.239 0.88 0.0047 0.251 0.93 1.2819 0.9997 SpOx1.1_005877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L04 compound treatment -0.0044 0.242 0.9 0.0067 0.253 0.94 1.295 0.9998 SpOx1.1_005878 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L05 compound treatment -0.0104 0.236 0.87 -0.0143 0.232 0.86 1.2244 1.0 SpOx1.1_005879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L06 compound treatment -0.0124 0.234 0.87 -0.0033 0.243 0.9 1.2479 0.9998 SpOx1.1_005880 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L07 compound treatment -0.0314 0.215 0.8 -0.0353 0.211 0.78 1.1143 1.0 SpOx1.1_005881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L08 compound treatment -0.0044 0.242 0.9 -3.0E-4 0.246 0.91 1.2766 1.0 SpOx1.1_005882 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L09 compound treatment -0.0024 0.244 0.9 0.0107 0.257 0.95 1.3107 0.9997 SpOx1.1_005883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L10 compound treatment -0.0234 0.223 0.83 -0.0123 0.234 0.87 1.1955 0.9997 SpOx1.1_005884 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L11 compound treatment -0.0034 0.243 0.9 7.0E-4 0.247 0.91 1.2819 1.0 SpOx1.1_005885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L12 compound treatment -0.0304 0.216 0.8 -0.0263 0.22 0.81 1.1406 1.0 2143583 SpOx1.1_005886 COC(=O)[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CCNC(=O)N)ccc17)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L13 compound treatment 0.0026 0.249 0.92 0.0067 0.253 0.94 1.3133 1.0 SpOx1.1_005887 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L14 compound treatment -0.0034 0.243 0.9 0.0037 0.25 0.92 1.2897 0.9999 SpOx1.1_005888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L15 compound treatment 0.0146 0.261 0.97 0.0137 0.26 0.96 1.363 1.0 SpOx1.1_005889 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L16 compound treatment -0.0084 0.238 0.88 -0.0113 0.235 0.87 1.2374 1.0 SpOx1.1_005890 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L17 compound treatment 0.0056 0.252 0.93 0.0067 0.253 0.94 1.3211 1.0 SpOx1.1_005891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L18 compound treatment 0.0026 0.249 0.92 -0.0033 0.243 0.9 1.2871 0.9999 SpOx1.1_005892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L19 compound treatment -4.0E-4 0.246 0.91 -0.0033 0.243 0.9 1.2792 1.0 SpOx1.1_005893 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L20 compound treatment -0.0314 0.215 0.8 -0.0383 0.208 0.77 1.1065 0.9999 SpOx1.1_005894 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L21 compound treatment -0.0064 0.24 0.89 -0.0053 0.241 0.89 1.2583 1.0 SpOx1.1_005895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L22 compound treatment 0.0156 0.262 0.97 0.0187 0.265 0.98 1.3787 1.0 SpOx1.1_005896 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L23 mock treatment 0.0136 0.26 0.96 0.0157 0.262 0.97 1.3657 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 L24 mock treatment -0.4885 -0.242 -0.89 -0.4891 -0.243 -0.9 -1.2698 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M01 compound treatment -0.0024 0.244 0.9 0.0117 0.258 0.95 1.3133 0.9996 SpOx1.1_005897 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M02 compound treatment 0.0116 0.258 0.95 0.0157 0.262 0.97 1.3604 1.0 SpOx1.1_005898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M03 compound treatment -4.0E-4 0.246 0.91 -0.0023 0.244 0.9 1.2819 1.0 SpOx1.1_005899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M04 compound treatment 0.0016 0.248 0.92 0.0087 0.255 0.94 1.3159 0.9999 SpOx1.1_005900 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M05 compound treatment -0.0134 0.233 0.86 -0.0113 0.235 0.87 1.2243 1.0 SpOx1.1_005901 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M06 compound treatment -0.0054 0.241 0.89 0.0057 0.252 0.93 1.2897 0.9998 SpOx1.1_005902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M07 compound treatment 0.0026 0.249 0.92 -3.0E-4 0.246 0.91 1.2949 1.0 SpOx1.1_005903 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M08 compound treatment -0.0084 0.238 0.88 -0.0033 0.243 0.9 1.2583 1.0 SpOx1.1_005904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M09 compound treatment -0.0144 0.232 0.86 -0.0033 0.243 0.9 1.2426 0.9997 SpOx1.1_005905 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M10 compound treatment -0.0144 0.232 0.86 -0.0103 0.236 0.87 1.2242 1.0 SpOx1.1_005906 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M11 compound treatment -0.0014 0.245 0.91 7.0E-4 0.247 0.91 1.2871 1.0 SpOx1.1_005907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M12 compound treatment -0.0824 0.164 0.61 -0.0763 0.17 0.63 0.8735 0.9999 SpOx1.1_005908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M13 compound treatment -0.0104 0.236 0.87 -0.0043 0.242 0.9 1.2506 0.9999 SpOx1.1_005909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M14 compound treatment -0.0104 0.236 0.87 0.0077 0.254 0.94 1.2819 0.9993 SpOx1.1_005910 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M15 compound treatment -0.0224 0.224 0.83 -0.0233 0.223 0.82 1.1693 1.0 SpOx1.1_005911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M16 compound treatment -0.0084 0.238 0.88 -0.0053 0.241 0.89 1.2532 1.0 SpOx1.1_005912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M17 compound treatment -0.0114 0.235 0.87 -0.0103 0.236 0.87 1.2321 1.0 SpOx1.1_005913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M18 compound treatment 6.0E-4 0.247 0.91 0.0037 0.25 0.92 1.3002 1.0 SpOx1.1_005914 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M19 compound treatment 0.0086 0.255 0.94 0.0117 0.258 0.95 1.3421 1.0 SpOx1.1_005915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M20 compound treatment -0.0254 0.221 0.82 -0.0293 0.217 0.8 1.1457 1.0 SpOx1.1_005916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M21 compound treatment 0.0076 0.254 0.94 0.0027 0.249 0.92 1.316 0.9999 SpOx1.1_005917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M22 compound treatment 0.0016 0.248 0.92 -0.0053 0.241 0.89 1.2792 0.9999 SpOx1.1_005918 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M23 mock treatment 0.0086 0.255 0.94 0.0077 0.254 0.94 1.3317 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 M24 mock treatment -0.4855 -0.239 -0.88 -0.4891 -0.243 -0.9 -1.262 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N01 compound treatment -0.0294 0.217 0.8 -0.0183 0.228 0.84 1.1642 0.9997 SpOx1.1_005919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N02 compound treatment -0.0154 0.231 0.85 -0.0153 0.231 0.85 1.2086 1.0 SpOx1.1_005920 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N03 compound treatment -4.0E-4 0.246 0.91 0.0087 0.255 0.94 1.3108 0.9998 SpOx1.1_005921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N04 compound treatment -0.0344 0.212 0.78 -0.0453 0.201 0.74 1.0802 0.9996 SpOx1.1_005922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N05 compound treatment -0.0104 0.236 0.87 -0.0093 0.237 0.88 1.2374 1.0 SpOx1.1_005923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N06 compound treatment -0.0194 0.227 0.84 -0.0203 0.226 0.84 1.1851 1.0 SpOx1.1_005924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N07 compound treatment -0.0414 0.205 0.76 -0.0433 0.203 0.75 1.0672 1.0 SpOx1.1_005925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N08 compound treatment -0.0574 0.189 0.7 -0.0493 0.197 0.73 1.0097 0.9998 SpOx1.1_005926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N09 compound treatment -0.0414 0.205 0.76 -0.0403 0.206 0.76 1.075 1.0 SpOx1.1_005927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N10 compound treatment -0.0104 0.236 0.87 -0.0033 0.243 0.9 1.2531 0.9999 SpOx1.1_005928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N11 compound treatment -0.0244 0.222 0.82 -0.0183 0.228 0.84 1.1771 0.9999 SpOx1.1_005929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N12 compound treatment 0.0016 0.248 0.92 0.0027 0.249 0.92 1.3002 1.0 SpOx1.1_005930 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N13 compound treatment -4.0E-4 0.246 0.91 -0.0103 0.236 0.87 1.261 0.9998 SpOx1.1_005931 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N14 compound treatment 0.0076 0.254 0.94 0.0047 0.251 0.93 1.3212 1.0 SpOx1.1_005932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N15 compound treatment -0.0214 0.225 0.83 -0.0213 0.225 0.83 1.1773 1.0 SpOx1.1_005933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N16 compound treatment -0.0124 0.234 0.87 -0.0153 0.231 0.85 1.2164 1.0 SpOx1.1_005934 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N17 compound treatment -0.0084 0.238 0.88 -0.0153 0.231 0.85 1.2269 0.9999 SpOx1.1_005935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N18 compound treatment -0.0114 0.235 0.87 -0.0133 0.233 0.86 1.2243 1.0 SpOx1.1_005936 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N19 compound treatment -0.0124 0.234 0.87 -0.0183 0.228 0.84 1.2086 0.9999 SpOx1.1_005937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N20 compound treatment -0.0044 0.242 0.9 -0.0113 0.235 0.87 1.2479 0.9999 SpOx1.1_005938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N21 compound treatment 0.0156 0.262 0.97 0.0187 0.265 0.98 1.3787 1.0 SpOx1.1_005939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N22 compound treatment -0.0024 0.244 0.9 7.0E-4 0.247 0.91 1.2846 1.0 SpOx1.1_005940 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N23 mock treatment 0.0136 0.26 0.96 0.0067 0.253 0.94 1.3421 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 N24 mock treatment -0.4905 -0.244 -0.9 -0.4901 -0.244 -0.91 -1.2777 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O01 compound treatment -0.0284 0.218 0.81 -0.0103 0.236 0.87 1.1876 0.9992 SpOx1.1_005941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O02 compound treatment 0.0036 0.25 0.93 0.0117 0.258 0.95 1.329 0.9999 SpOx1.1_005942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O03 compound treatment -0.0014 0.245 0.91 0.0037 0.25 0.92 1.295 1.0 SpOx1.1_005943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O04 compound treatment -4.0E-4 0.246 0.91 0.0037 0.25 0.92 1.2976 1.0 SpOx1.1_005944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O05 compound treatment -0.0074 0.239 0.88 -3.0E-4 0.246 0.91 1.2688 0.9999 SpOx1.1_005945 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O06 compound treatment -0.0024 0.244 0.9 -0.0043 0.242 0.89 1.2714 1.0 SpOx1.1_005946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O07 compound treatment -0.0334 0.213 0.79 -0.0333 0.213 0.79 1.1144 1.0 SpOx1.1_005947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O08 compound treatment -0.0024 0.244 0.9 0.0037 0.25 0.92 1.2924 0.9999 SpOx1.1_005948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O09 compound treatment -0.0214 0.225 0.83 -0.0163 0.23 0.85 1.1904 0.9999 SpOx1.1_005949 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O10 compound treatment -0.0244 0.222 0.82 -0.0143 0.232 0.86 1.1876 0.9998 SpOx1.1_005950 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O11 compound treatment -0.0064 0.24 0.89 -0.0123 0.234 0.87 1.2401 0.9999 SpOx1.1_005951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O12 compound treatment 0.0026 0.249 0.92 -0.0013 0.245 0.91 1.2923 1.0 SpOx1.1_005952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O13 compound treatment -0.0094 0.237 0.88 -0.0113 0.235 0.87 1.2348 1.0 SpOx1.1_005953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O14 compound treatment -0.0204 0.226 0.84 -0.0143 0.232 0.86 1.198 0.9999 SpOx1.1_005954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O15 compound treatment 0.0126 0.259 0.96 0.0077 0.254 0.94 1.3421 0.9999 SpOx1.1_005955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O16 compound treatment -0.0074 0.239 0.88 -0.0123 0.234 0.87 1.2374 0.9999 SpOx1.1_005956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O17 compound treatment -0.0074 0.239 0.88 -0.0083 0.238 0.88 1.2478 1.0 SpOx1.1_005957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O18 compound treatment -0.0074 0.239 0.88 -0.0083 0.238 0.88 1.2478 1.0 SpOx1.1_005958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O19 compound treatment -0.0254 0.221 0.82 -0.0253 0.221 0.82 1.1562 1.0 SpOx1.1_005959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O20 compound treatment 6.0E-4 0.247 0.91 -0.0193 0.227 0.84 1.2399 0.9991 SpOx1.1_005960 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O21 compound treatment 0.0186 0.265 0.98 0.0127 0.259 0.96 1.3708 0.9999 SpOx1.1_005961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O22 compound treatment 0.0056 0.252 0.93 0.0057 0.252 0.93 1.3185 1.0 SpOx1.1_005962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O23 mock treatment 0.0186 0.265 0.98 0.0137 0.26 0.96 1.3735 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 O24 mock treatment -0.4885 -0.242 -0.89 -0.4871 -0.241 -0.89 -1.2646 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P01 compound treatment -0.0374 0.209 0.77 -0.0203 0.226 0.84 1.138 0.9993 SpOx1.1_005963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P02 compound treatment -0.0184 0.228 0.84 -0.0083 0.238 0.88 1.2191 0.9998 SpOx1.1_005964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P03 compound treatment -0.0254 0.221 0.82 -0.0263 0.22 0.81 1.1537 1.0 SpOx1.1_005965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P04 compound treatment -0.0154 0.231 0.85 -0.0133 0.233 0.86 1.2138 1.0 SpOx1.1_005966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P05 compound treatment -0.0354 0.211 0.78 -0.0373 0.209 0.77 1.0986 1.0 SpOx1.1_005967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P06 compound treatment -0.0154 0.231 0.85 -0.0123 0.234 0.87 1.2164 1.0 SpOx1.1_005968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P07 compound treatment -0.0374 0.209 0.77 -0.0373 0.209 0.77 1.0934 1.0 SpOx1.1_005969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P08 compound treatment -0.0304 0.216 0.8 -0.0243 0.222 0.82 1.1458 0.9999 SpOx1.1_005970 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P09 compound treatment -0.0174 0.229 0.85 -0.0183 0.228 0.84 1.1955 1.0 SpOx1.1_005971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P10 compound treatment -0.0284 0.218 0.81 -0.0313 0.215 0.79 1.1326 1.0 SpOx1.1_005972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P11 compound treatment -0.0954 0.151 0.56 -0.0853 0.161 0.59 0.816 0.9995 2142863 SpOx1.1_005973 COC(=O)[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CCn8nnc9ccccc89)ccc17)C(C)C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P12 compound treatment -0.0204 0.226 0.84 -0.0273 0.219 0.81 1.1641 0.9999 SpOx1.1_005974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P13 compound treatment -0.0194 0.227 0.84 -0.0233 0.223 0.82 1.1772 1.0 SpOx1.1_005975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P14 compound treatment -0.0104 0.236 0.87 -0.0063 0.24 0.89 1.2453 1.0 SpOx1.1_005976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P15 compound treatment -0.0264 0.22 0.81 -0.0253 0.221 0.82 1.1537 1.0 SpOx1.1_005977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P16 compound treatment -0.0204 0.226 0.84 -0.0223 0.224 0.83 1.1771 1.0 SpOx1.1_005978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P17 compound treatment -0.0124 0.234 0.87 -0.0203 0.226 0.84 1.2033 0.9998 SpOx1.1_005979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P18 compound treatment -0.0294 0.217 0.8 -0.0303 0.216 0.8 1.1328 1.0 SpOx1.1_005980 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P19 compound treatment -0.0144 0.232 0.86 -0.0203 0.226 0.84 1.1981 0.9999 SpOx1.1_005981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P20 compound treatment -0.0144 0.232 0.86 -0.0133 0.233 0.86 1.2164 1.0 SpOx1.1_005982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P21 compound treatment -0.0154 0.231 0.85 -0.0133 0.233 0.86 1.2138 1.0 SpOx1.1_005983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P22 compound treatment -0.0194 0.227 0.84 -0.0173 0.229 0.85 1.1929 1.0 SpOx1.1_005984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P23 mock treatment 0.0016 0.248 0.92 -0.0313 0.215 0.79 1.2111 0.9974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1295 P24 mock treatment -0.4855 -0.239 -0.88 -0.4901 -0.244 -0.91 -1.2646 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A01 compound treatment -0.0565 0.186 0.69 -0.082 0.161 0.59 0.9066 0.9974 SpOx1.1_005985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A02 compound treatment -0.0515 0.191 0.71 -0.076 0.166 0.62 0.9353 0.9978 SpOx1.1_005986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A03 compound treatment -0.0885 0.154 0.57 -0.057 0.185 0.69 0.8883 0.9956 SpOx1.1_005987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A04 compound treatment -0.0795 0.163 0.6 -0.07 0.172 0.64 0.8778 0.9996 SpOx1.1_005988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A05 compound treatment -0.0705 0.172 0.64 -0.07 0.172 0.64 0.9013 1.0 SpOx1.1_005989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A06 compound treatment -0.0735 0.169 0.62 -0.074 0.169 0.62 0.883 1.0 SpOx1.1_005990 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A07 compound treatment -0.0959 0.146 0.54 -0.032 0.21 0.78 0.9344 0.9841 SpOx1.1_005991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A08 compound treatment -0.0625 0.18 0.67 -0.063 0.179 0.67 0.9406 1.0 SpOx1.1_005992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A09 compound treatment -0.0555 0.187 0.69 -0.084 0.159 0.59 0.9039 0.9967 SpOx1.1_005993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A10 compound treatment -0.0665 0.176 0.65 -0.081 0.162 0.6 0.883 0.9991 SpOx1.1_005994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A11 compound treatment -0.0595 0.183 0.68 -0.076 0.166 0.62 0.9144 0.999 SpOx1.1_005995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A12 compound treatment -0.0585 0.184 0.68 -0.074 0.168 0.62 0.9222 0.9991 SpOx1.1_005996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A13 compound treatment -0.0735 0.169 0.62 -0.085 0.158 0.58 0.8542 0.9994 SpOx1.1_005997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A14 compound treatment -0.0655 0.177 0.65 -0.0863 0.156 0.58 0.8718 0.9981 SpOx1.1_005998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A15 compound treatment -0.0625 0.18 0.67 -0.062 0.181 0.67 0.9433 1.0 2144728 SpOx1.1_005999 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A16 compound treatment -0.0665 0.176 0.65 -0.0833 0.159 0.59 0.877 0.9988 SpOx1.1_006000 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A17 compound treatment -0.0775 0.165 0.61 -0.082 0.161 0.59 0.8516 0.9999 SpOx1.1_006001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A18 compound treatment -0.0635 0.179 0.66 -0.078 0.164 0.61 0.8987 0.9992 SpOx1.1_006002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A19 compound treatment -0.0695 0.173 0.64 -0.077 0.166 0.61 0.8856 0.9998 SpOx1.1_006003 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A20 compound treatment -0.0815 0.161 0.59 -0.077 0.166 0.61 0.8542 0.9999 SpOx1.1_006004 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A21 compound treatment -0.0635 0.179 0.66 -0.0893 0.153 0.57 0.8691 0.9971 SpOx1.1_006005 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A22 compound treatment -0.0745 0.168 0.62 -0.0913 0.151 0.56 0.8351 0.9987 SpOx1.1_006006 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A23 mock treatment -0.0595 0.183 0.68 -0.071 0.172 0.64 0.9275 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 A24 mock treatment -0.4786 -0.236 -0.87 -0.4787 -0.236 -0.88 -1.2366 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B01 compound treatment -0.0035 0.239 0.88 -0.006 0.237 0.88 1.2442 1.0 SpOx1.1_006007 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B02 compound treatment -0.0035 0.239 0.88 -0.003 0.24 0.89 1.2521 1.0 2142980 SpOx1.1_006008 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)N(C(=O)N[C@H](C)c7ccccc7)c8ccc(C#CCNC(=O)N)cc86)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B03 compound treatment 0.0085 0.251 0.93 0.013 0.256 0.95 1.3253 0.9999 SpOx1.1_006009 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B04 compound treatment -0.0045 0.238 0.88 0.012 0.255 0.94 1.2888 0.9994 SpOx1.1_006010 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B05 compound treatment -5.0E-4 0.242 0.89 0.003 0.246 0.91 1.2756 1.0 SpOx1.1_006011 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B06 compound treatment -0.0355 0.207 0.76 -0.054 0.189 0.7 1.0347 0.999 SpOx1.1_006012 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B07 compound treatment -0.0095 0.233 0.86 -0.009 0.234 0.87 1.2207 1.0 SpOx1.1_006013 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B08 compound treatment 0.0145 0.257 0.95 0.012 0.254 0.94 1.3383 1.0 SpOx1.1_006014 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B09 compound treatment -5.0E-4 0.242 0.89 -0.023 0.22 0.81 1.2075 0.9989 SpOx1.1_006015 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B10 compound treatment 0.0135 0.256 0.95 -0.001 0.242 0.89 1.3017 0.9996 SpOx1.1_006016 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B11 compound treatment -0.0045 0.238 0.88 -0.019 0.224 0.83 1.2076 0.9996 SpOx1.1_006017 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B12 compound treatment 0.0025 0.245 0.91 -0.01 0.233 0.86 1.2495 0.9997 SpOx1.1_006018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B13 compound treatment 0.0145 0.257 0.95 -0.005 0.238 0.88 1.2939 0.9993 SpOx1.1_006019 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B14 compound treatment 0.0025 0.245 0.91 0.007 0.25 0.92 1.2939 0.9999 SpOx1.1_006020 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B15 compound treatment 0.0015 0.244 0.9 -0.001 0.242 0.89 1.2704 1.0 SpOx1.1_006021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B16 compound treatment -0.0065 0.236 0.87 -0.005 0.238 0.88 1.239 1.0 SpOx1.1_006022 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B17 compound treatment 0.0115 0.254 0.94 0.013 0.256 0.95 1.3332 1.0 SpOx1.1_006023 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B18 compound treatment -0.0045 0.238 0.88 0.001 0.244 0.9 1.2599 0.9999 SpOx1.1_006024 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B19 compound treatment 0.0065 0.249 0.92 -0.008 0.235 0.87 1.2651 0.9996 SpOx1.1_006025 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B20 compound treatment 0.0155 0.258 0.95 0.006 0.248 0.92 1.3252 0.9998 SpOx1.1_006026 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B21 compound treatment 0.0245 0.267 0.99 0.005 0.248 0.92 1.3462 0.9993 SpOx1.1_006027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B22 compound treatment -0.0105 0.232 0.86 -0.02 0.223 0.82 1.1893 0.9998 2143544 SpOx1.1_006028 COc1ccc(C#Cc2ccc3N(C(=O)N[C@H](C)c4ccccc4)C(=O)[C@]5([C@@H]([C@@H]6N([C@@H]5c7cccc(OCCO)c7)[C@H]([C@H](OC6=O)c8ccccc8)c9ccccc9)C(=O)O)c3c2)cc1 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B23 mock treatment 5.0E-4 0.243 0.9 0.013 0.255 0.95 1.3044 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 B24 mock treatment -0.4796 -0.237 -0.88 -0.4797 -0.237 -0.88 -1.2418 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C01 compound treatment -0.0075 0.235 0.87 -0.005 0.238 0.88 1.2364 1.0 SpOx1.1_006029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C02 compound treatment -0.0105 0.232 0.86 0.006 0.249 0.92 1.2573 0.9994 SpOx1.1_006030 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C03 compound treatment -0.0145 0.228 0.84 -0.007 0.236 0.87 1.2129 0.9998 SpOx1.1_006031 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C04 compound treatment -0.0325 0.21 0.78 -0.017 0.226 0.84 1.1396 0.9993 SpOx1.1_006032 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C05 compound treatment -0.0275 0.215 0.79 -0.006 0.237 0.88 1.1814 0.9988 SpOx1.1_006033 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C06 compound treatment -0.0015 0.241 0.89 -0.009 0.234 0.87 1.2416 0.9999 SpOx1.1_006034 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C07 compound treatment -0.0065 0.236 0.87 -0.01 0.233 0.86 1.2259 1.0 SpOx1.1_006035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C08 compound treatment 0.0025 0.245 0.91 -0.002 0.241 0.89 1.2704 1.0 SpOx1.1_006036 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C09 compound treatment -0.0035 0.239 0.88 -0.01 0.233 0.86 1.2338 0.9999 SpOx1.1_006037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C10 compound treatment -0.0285 0.214 0.79 -0.052 0.191 0.71 1.0583 0.9984 SpOx1.1_006038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C11 compound treatment -0.0075 0.235 0.87 -0.009 0.234 0.87 1.2259 1.0 SpOx1.1_006039 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C12 compound treatment -0.0095 0.233 0.86 -0.014 0.229 0.85 1.2077 1.0 SpOx1.1_006040 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C13 compound treatment -0.0055 0.237 0.88 -0.014 0.229 0.85 1.2181 0.9999 SpOx1.1_006041 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C14 compound treatment -0.0025 0.24 0.89 -0.025 0.218 0.81 1.197 0.9989 SpOx1.1_006042 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C15 compound treatment -0.0035 0.239 0.88 -0.013 0.23 0.85 1.2259 0.9998 SpOx1.1_006043 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C16 compound treatment -0.0025 0.24 0.89 -0.006 0.237 0.88 1.2468 1.0 SpOx1.1_006044 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C17 compound treatment 0.0065 0.249 0.92 0.0 0.243 0.9 1.2861 0.9999 SpOx1.1_006045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C18 compound treatment -0.0015 0.241 0.89 -0.005 0.238 0.88 1.252 1.0 SpOx1.1_006046 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C19 compound treatment 0.0065 0.249 0.92 -0.01 0.233 0.86 1.2598 0.9995 SpOx1.1_006047 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C20 compound treatment -5.0E-4 0.242 0.89 -0.012 0.23 0.85 1.2362 0.9997 SpOx1.1_006048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C21 compound treatment 0.0055 0.248 0.92 -0.013 0.229 0.85 1.2493 0.9993 SpOx1.1_006049 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C22 compound treatment -0.0505 0.192 0.71 -0.059 0.184 0.68 0.9824 0.9998 SpOx1.1_006050 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C23 mock treatment -0.0205 0.222 0.82 -0.02 0.222 0.82 1.1631 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 C24 mock treatment -0.4806 -0.238 -0.88 -0.4777 -0.235 -0.87 -1.2392 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D01 compound treatment -0.0195 0.223 0.82 -0.017 0.226 0.84 1.1735 1.0 SpOx1.1_006051 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D02 compound treatment -0.0155 0.227 0.84 -0.025 0.218 0.81 1.1631 0.9998 SpOx1.1_006052 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D03 compound treatment -0.0045 0.238 0.88 -0.018 0.225 0.83 1.2102 0.9996 SpOx1.1_006053 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D04 compound treatment 0.0025 0.245 0.91 -0.041 0.202 0.75 1.1682 0.9954 SpOx1.1_006054 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D05 compound treatment -0.0065 0.236 0.87 -0.027 0.216 0.8 1.1814 0.999 SpOx1.1_006055 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D06 compound treatment -0.0185 0.224 0.83 -0.017 0.226 0.84 1.1762 1.0 SpOx1.1_006056 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D07 compound treatment -0.0135 0.229 0.85 -0.007 0.236 0.87 1.2155 0.9999 SpOx1.1_006057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D08 compound treatment 0.0105 0.253 0.93 -0.013 0.23 0.85 1.2624 0.9989 SpOx1.1_006058 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D09 compound treatment -0.0135 0.229 0.85 -0.02 0.223 0.82 1.1815 0.9999 SpOx1.1_006059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D10 compound treatment -5.0E-4 0.242 0.89 -0.035 0.207 0.77 1.176 0.9972 SpOx1.1_006060 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D11 compound treatment 0.0085 0.251 0.93 -0.007 0.236 0.87 1.273 0.9995 SpOx1.1_006061 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D12 compound treatment 5.0E-4 0.243 0.9 -0.02 0.222 0.82 1.218 0.9991 SpOx1.1_006062 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D13 compound treatment -0.0065 0.236 0.87 0.001 0.244 0.9 1.2548 0.9999 SpOx1.1_006063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D14 compound treatment 0.0165 0.259 0.96 -0.02 0.222 0.82 1.2597 0.9972 SpOx1.1_006064 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D15 compound treatment -0.0055 0.237 0.88 -0.023 0.22 0.81 1.1946 0.9993 SpOx1.1_006065 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D16 compound treatment 0.0105 0.253 0.93 -0.009 0.234 0.87 1.273 0.9993 SpOx1.1_006066 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D17 compound treatment 0.0015 0.244 0.9 -0.017 0.226 0.84 1.2284 0.9993 SpOx1.1_006067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D18 compound treatment 0.0015 0.244 0.9 -0.01 0.233 0.86 1.2468 0.9997 SpOx1.1_006068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D19 compound treatment -0.0405 0.202 0.75 -0.052 0.191 0.71 1.0269 0.9996 SpOx1.1_006069 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D20 compound treatment -0.0075 0.235 0.87 -0.006 0.237 0.88 1.2337 1.0 SpOx1.1_006070 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D21 compound treatment -0.0375 0.205 0.76 -0.068 0.175 0.65 0.9928 0.9969 SpOx1.1_006071 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D22 compound treatment -5.0E-4 0.242 0.89 -0.005 0.238 0.88 1.2547 1.0 SpOx1.1_006072 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D23 mock treatment 0.0105 0.253 0.94 -0.007 0.235 0.87 1.2782 0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 D24 mock treatment -0.4796 -0.237 -0.88 -0.4777 -0.235 -0.87 -1.2366 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E01 compound treatment -5.0E-4 0.242 0.89 -0.005 0.238 0.88 1.2546 1.0 SpOx1.1_006073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E02 compound treatment -0.0275 0.215 0.79 -0.036 0.207 0.77 1.1028 0.9998 SpOx1.1_006074 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E03 compound treatment -0.0115 0.231 0.85 0.004 0.247 0.91 1.2495 0.9994 SpOx1.1_006075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E04 compound treatment -0.0345 0.208 0.77 -0.028 0.215 0.79 1.1055 0.9999 SpOx1.1_006076 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E05 compound treatment 0.0035 0.246 0.91 0.012 0.255 0.94 1.3096 0.9998 SpOx1.1_006077 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E06 compound treatment 0.0085 0.251 0.93 0.014 0.256 0.95 1.3279 0.9999 SpOx1.1_006078 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E07 compound treatment 0.0015 0.244 0.9 0.006 0.249 0.92 1.2887 0.9999 SpOx1.1_006079 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E08 compound treatment -0.0015 0.241 0.89 0.012 0.255 0.94 1.2967 0.9996 SpOx1.1_006080 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E09 compound treatment -5.0E-4 0.242 0.89 0.004 0.247 0.91 1.2782 0.9999 SpOx1.1_006081 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E10 compound treatment 0.0105 0.253 0.93 -0.002 0.241 0.89 1.2913 0.9997 SpOx1.1_006082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E11 compound treatment -5.0E-4 0.242 0.89 -0.028 0.214 0.79 1.1943 0.9983 SpOx1.1_006083 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E12 compound treatment 0.0015 0.244 0.9 0.001 0.244 0.9 1.2756 1.0 SpOx1.1_006084 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E13 compound treatment 0.0055 0.248 0.92 0.008 0.251 0.93 1.3044 1.0 SpOx1.1_006085 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E14 compound treatment 0.0075 0.25 0.92 -0.009 0.234 0.87 1.2652 0.9995 SpOx1.1_006086 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E15 compound treatment 0.0115 0.254 0.94 0.026 0.268 0.99 1.3672 0.9996 SpOx1.1_006087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E16 compound treatment 0.0085 0.251 0.93 -0.005 0.238 0.88 1.2782 0.9997 SpOx1.1_006088 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E17 compound treatment 0.0195 0.262 0.97 -0.007 0.236 0.87 1.3017 0.9987 SpOx1.1_006089 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E18 compound treatment 0.0205 0.263 0.97 0.01 0.252 0.94 1.3488 0.9998 SpOx1.1_006090 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E19 compound treatment 0.0075 0.25 0.92 -0.011 0.232 0.86 1.2598 0.9993 SpOx1.1_006091 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E20 compound treatment 5.0E-4 0.243 0.9 -0.001 0.242 0.89 1.2677 1.0 SpOx1.1_006092 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E21 compound treatment 0.0055 0.248 0.92 -0.004 0.239 0.88 1.273 0.9998 SpOx1.1_006093 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E22 compound treatment -0.0125 0.23 0.85 -0.026 0.217 0.8 1.1682 0.9996 2142264 SpOx1.1_006094 COc1ccc(C#Cc2ccc3N(C(=O)N[C@H](C)c4ccccc4)C(=O)[C@@]5([C@H]([C@H]6N([C@H]5c7cccc(OCCO)c7)[C@@H]([C@@H](OC6=O)c8ccccc8)c9ccccc9)C(=O)O)c3c2)cc1 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E23 mock treatment 0.0065 0.249 0.92 0.002 0.245 0.91 1.2914 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 E24 mock treatment -0.4786 -0.236 -0.87 -0.4777 -0.235 -0.87 -1.2339 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F01 compound treatment -0.0105 0.232 0.86 -0.013 0.23 0.85 1.2076 1.0 SpOx1.1_006095 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F02 compound treatment -0.0185 0.224 0.83 -0.01 0.233 0.86 1.1945 0.9998 SpOx1.1_006096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F03 compound treatment -5.0E-4 0.242 0.89 -0.002 0.241 0.89 1.2625 1.0 SpOx1.1_006097 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F04 compound treatment -0.0145 0.228 0.84 -0.039 0.204 0.75 1.129 0.9985 SpOx1.1_006098 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F05 compound treatment -0.0155 0.227 0.84 0.005 0.248 0.92 1.2416 0.999 SpOx1.1_006099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F06 compound treatment 0.0135 0.256 0.95 0.012 0.255 0.94 1.3358 1.0 SpOx1.1_006100 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F07 compound treatment -5.0E-4 0.242 0.89 0.004 0.247 0.91 1.2783 0.9999 SpOx1.1_006101 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F08 compound treatment 0.0155 0.258 0.95 0.007 0.249 0.92 1.3279 0.9999 SpOx1.1_006102 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F09 compound treatment 0.0105 0.253 0.94 -0.018 0.224 0.83 1.2493 0.9983 SpOx1.1_006103 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F10 compound treatment 0.0125 0.255 0.94 0.002 0.245 0.91 1.3071 0.9998 SpOx1.1_006104 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F11 compound treatment 0.0085 0.251 0.93 -0.015 0.228 0.84 1.2521 0.9989 SpOx1.1_006105 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F12 compound treatment -5.0E-4 0.242 0.89 -0.006 0.237 0.88 1.2522 0.9999 SpOx1.1_006106 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F13 compound treatment 0.0105 0.253 0.94 0.017 0.26 0.96 1.3411 0.9999 SpOx1.1_006107 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F14 compound treatment 0.0165 0.259 0.96 -0.007 0.236 0.87 1.2939 0.9989 SpOx1.1_006108 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F15 compound treatment 0.0215 0.264 0.98 0.002 0.245 0.91 1.3305 0.9993 SpOx1.1_006109 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F16 compound treatment 0.0165 0.259 0.96 0.005 0.248 0.92 1.3253 0.9998 SpOx1.1_006110 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F17 compound treatment -0.0045 0.238 0.88 -0.014 0.229 0.85 1.2207 0.9998 SpOx1.1_006111 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F18 compound treatment 0.0155 0.258 0.95 -0.012 0.231 0.85 1.2782 0.9985 SpOx1.1_006112 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F19 compound treatment 0.0025 0.245 0.91 -0.4487 -0.206 -0.76 0.0999 0.0844 SpOx1.1_006113 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F20 compound treatment 0.0065 0.249 0.92 -0.009 0.234 0.87 1.2625 0.9995 SpOx1.1_006114 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F21 compound treatment 0.0165 0.259 0.96 -0.001 0.242 0.89 1.3096 0.9994 SpOx1.1_006115 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F22 compound treatment 0.0135 0.256 0.95 0.0 0.243 0.9 1.3044 0.9997 SpOx1.1_006116 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F23 mock treatment -0.0055 0.237 0.88 0.01 0.253 0.94 1.2809 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 F24 mock treatment -0.479 -0.237 -0.88 -0.4787 -0.236 -0.88 -1.2376 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G01 compound treatment -0.0165 0.226 0.84 0.0 0.243 0.9 1.2259 0.9993 SpOx1.1_006117 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G02 compound treatment -0.0105 0.232 0.86 -0.012 0.23 0.85 1.2102 1.0 SpOx1.1_006118 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G03 compound treatment -0.0105 0.232 0.86 -0.013 0.23 0.85 1.2076 1.0 SpOx1.1_006119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G04 compound treatment -0.0125 0.23 0.85 -0.003 0.24 0.89 1.2285 0.9998 SpOx1.1_006120 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G05 compound treatment -0.0015 0.241 0.89 0.0 0.243 0.9 1.2652 1.0 SpOx1.1_006121 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G06 compound treatment 0.0025 0.245 0.91 -0.003 0.24 0.89 1.2677 1.0 SpOx1.1_006122 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G07 compound treatment 0.0055 0.248 0.92 0.017 0.259 0.96 1.3279 0.9997 SpOx1.1_006123 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G08 compound treatment -0.0055 0.237 0.88 0.001 0.244 0.9 1.2574 0.9999 SpOx1.1_006124 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G09 compound treatment 0.0045 0.247 0.91 -0.004 0.239 0.88 1.2704 0.9999 SpOx1.1_006125 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G10 compound treatment 0.0085 0.251 0.93 -0.016 0.227 0.84 1.2494 0.9988 SpOx1.1_006126 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G11 compound treatment -0.0135 0.229 0.85 -0.012 0.231 0.85 1.2025 1.0 2144744 SpOx1.1_006127 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19)c%10ccccc%10 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G12 compound treatment -0.0015 0.241 0.89 -0.017 0.226 0.84 1.2207 0.9995 SpOx1.1_006128 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G13 compound treatment -0.0025 0.24 0.89 0.006 0.249 0.92 1.2783 0.9998 SpOx1.1_006129 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G14 compound treatment -0.0035 0.239 0.88 -0.02 0.223 0.82 1.2077 0.9994 SpOx1.1_006130 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G15 compound treatment -0.0015 0.241 0.89 -0.007 0.236 0.87 1.2469 0.9999 SpOx1.1_006131 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G16 compound treatment -0.0135 0.229 0.85 -0.022 0.221 0.82 1.1763 0.9998 SpOx1.1_006132 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G17 compound treatment -0.0185 0.224 0.83 -0.023 0.22 0.81 1.1605 1.0 SpOx1.1_006133 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G18 compound treatment -0.0075 0.235 0.87 -0.011 0.232 0.86 1.2207 1.0 SpOx1.1_006134 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G19 compound treatment -0.0145 0.228 0.84 -0.016 0.227 0.84 1.1894 1.0 SpOx1.1_006135 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G20 compound treatment -0.0045 0.238 0.88 -0.032 0.21 0.78 1.1734 0.9982 SpOx1.1_006136 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G21 compound treatment -0.0175 0.225 0.83 -0.018 0.225 0.83 1.1762 1.0 SpOx1.1_006137 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G22 compound treatment -0.0195 0.223 0.82 -0.034 0.209 0.77 1.129 0.9995 SpOx1.1_006138 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G23 mock treatment -0.0065 0.236 0.87 -0.01 0.232 0.86 1.2259 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 G24 mock treatment -0.4796 -0.237 -0.88 -0.4787 -0.236 -0.88 -1.2392 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H01 compound treatment -0.0075 0.235 0.87 -0.006 0.237 0.88 1.2337 1.0 SpOx1.1_006139 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H02 compound treatment -0.0015 0.241 0.89 -0.029 0.214 0.79 1.1891 0.9983 SpOx1.1_006140 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H03 compound treatment -0.0205 0.222 0.82 -0.007 0.236 0.87 1.1972 0.9995 SpOx1.1_006141 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H04 compound treatment -0.0125 0.23 0.85 -0.023 0.22 0.81 1.1762 0.9998 SpOx1.1_006142 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H05 compound treatment -0.0015 0.241 0.89 -0.005 0.238 0.88 1.252 1.0 SpOx1.1_006143 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H06 compound treatment -0.0175 0.225 0.83 -0.017 0.226 0.84 1.1788 1.0 SpOx1.1_006144 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H07 compound treatment -0.0035 0.239 0.88 -0.018 0.225 0.83 1.2128 0.9996 SpOx1.1_006145 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H08 compound treatment 5.0E-4 0.243 0.9 -0.019 0.224 0.83 1.2207 0.9992 SpOx1.1_006146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H09 compound treatment -0.0115 0.231 0.85 -0.017 0.226 0.84 1.1946 0.9999 SpOx1.1_006147 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H10 compound treatment 0.0165 0.259 0.96 -0.018 0.225 0.83 1.2651 0.9976 SpOx1.1_006148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H11 compound treatment 0.0015 0.244 0.9 -0.025 0.217 0.81 1.2075 0.9984 SpOx1.1_006149 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H12 compound treatment -0.0055 0.237 0.88 -0.04 0.203 0.75 1.15 0.997 SpOx1.1_006150 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H13 compound treatment -0.0145 0.228 0.84 -0.005 0.238 0.88 1.2181 0.9998 SpOx1.1_006151 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H14 compound treatment -5.0E-4 0.242 0.89 -0.004 0.239 0.88 1.2573 1.0 SpOx1.1_006152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H15 compound treatment 0.0015 0.244 0.9 -0.015 0.228 0.84 1.2338 0.9994 SpOx1.1_006153 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H16 compound treatment -0.0025 0.24 0.89 -0.01 0.233 0.86 1.2363 0.9999 SpOx1.1_006154 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H17 compound treatment -0.0355 0.207 0.76 -0.041 0.202 0.75 1.0688 0.9999 SpOx1.1_006155 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H18 compound treatment -0.0105 0.232 0.86 -0.022 0.22 0.82 1.1839 0.9997 SpOx1.1_006156 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H19 compound treatment 0.0025 0.245 0.91 -0.011 0.232 0.86 1.2468 0.9996 SpOx1.1_006157 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H20 compound treatment 5.0E-4 0.243 0.9 -0.015 0.227 0.84 1.2311 0.9995 SpOx1.1_006158 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H21 compound treatment -0.0095 0.233 0.86 -0.026 0.217 0.8 1.1762 0.9994 SpOx1.1_006159 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H22 compound treatment -0.0085 0.234 0.86 -0.024 0.219 0.81 1.184 0.9995 SpOx1.1_006160 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H23 mock treatment 0.0135 0.256 0.95 -0.014 0.228 0.85 1.2677 0.9985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 H24 mock treatment -0.4826 -0.24 -0.89 -0.4807 -0.238 -0.88 -1.2523 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I01 compound treatment -0.0035 0.239 0.88 0.012 0.254 0.94 1.2913 0.9995 SpOx1.1_006161 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I02 compound treatment -0.0115 0.231 0.85 -0.02 0.223 0.82 1.1866 0.9999 SpOx1.1_006162 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I03 compound treatment -0.0065 0.236 0.87 0.013 0.256 0.95 1.2861 0.9992 SpOx1.1_006163 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I04 compound treatment -0.0295 0.213 0.79 -0.02 0.223 0.82 1.1396 0.9997 SpOx1.1_006164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I05 compound treatment 0.0075 0.25 0.92 -0.005 0.238 0.88 1.2757 0.9997 SpOx1.1_006165 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I06 compound treatment -0.0055 0.237 0.88 -0.011 0.232 0.86 1.2259 0.9999 SpOx1.1_006166 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I07 compound treatment 0.0015 0.244 0.9 -0.002 0.241 0.89 1.2678 1.0 SpOx1.1_006167 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I08 compound treatment -0.0145 0.228 0.84 -0.054 0.189 0.7 1.0898 0.9957 SpOx1.1_006168 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I09 compound treatment -0.0085 0.234 0.86 0.009 0.252 0.93 1.2705 0.9993 SpOx1.1_006169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I10 compound treatment 0.0125 0.255 0.94 0.003 0.245 0.91 1.3096 0.9998 SpOx1.1_006170 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I11 compound treatment 0.0075 0.25 0.92 -0.027 0.216 0.8 1.218 0.9974 SpOx1.1_006171 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I12 compound treatment -0.0055 0.237 0.88 -0.008 0.235 0.87 1.2339 1.0 SpOx1.1_006172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I13 compound treatment 0.0015 0.244 0.9 -0.018 0.225 0.83 1.2259 0.9992 SpOx1.1_006173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I14 compound treatment -0.0025 0.24 0.89 -0.015 0.228 0.84 1.2234 0.9997 SpOx1.1_006174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I15 compound treatment -0.0045 0.238 0.88 -0.031 0.212 0.78 1.1762 0.9983 SpOx1.1_006175 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I16 compound treatment -0.0135 0.229 0.85 -0.03 0.212 0.79 1.1552 0.9994 2143744 SpOx1.1_006176 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CCN(C)Cc8ccccc8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I17 compound treatment -0.0125 0.23 0.85 -0.002 0.241 0.89 1.2311 0.9997 SpOx1.1_006177 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I18 compound treatment -0.0415 0.201 0.74 -0.018 0.225 0.83 1.1134 0.9984 SpOx1.1_006178 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I19 compound treatment -0.0375 0.205 0.76 -0.093 0.15 0.55 0.9273 0.9882 SpOx1.1_006179 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I20 compound treatment -0.0045 0.238 0.88 -0.009 0.234 0.87 1.2338 1.0 SpOx1.1_006180 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I21 compound treatment -0.0155 0.227 0.84 -0.001 0.242 0.89 1.226 0.9995 SpOx1.1_006181 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I22 compound treatment 0.0025 0.245 0.91 -0.015 0.228 0.84 1.2364 0.9994 SpOx1.1_006182 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I23 mock treatment 5.0E-4 0.243 0.9 0.005 0.248 0.92 1.2835 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 I24 mock treatment -0.4796 -0.237 -0.88 -0.4807 -0.238 -0.88 -1.2444 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J01 compound treatment -0.0185 0.224 0.83 -0.009 0.234 0.87 1.1972 0.9998 SpOx1.1_006183 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J02 compound treatment -0.0205 0.222 0.82 -0.018 0.225 0.83 1.1683 1.0 SpOx1.1_006184 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J03 compound treatment -0.0395 0.203 0.75 -0.021 0.222 0.82 1.1108 0.999 SpOx1.1_006185 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J04 compound treatment -0.0255 0.217 0.8 -0.027 0.216 0.8 1.1317 1.0 SpOx1.1_006186 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J05 compound treatment -0.0245 0.218 0.81 -0.03 0.213 0.79 1.1265 0.9999 SpOx1.1_006187 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J06 compound treatment -0.0065 0.236 0.87 -0.02 0.223 0.82 1.1997 0.9996 SpOx1.1_006188 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J07 compound treatment -0.0165 0.226 0.84 -0.01 0.233 0.86 1.1998 0.9999 SpOx1.1_006189 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J08 compound treatment -0.0165 0.226 0.84 -0.018 0.225 0.83 1.1788 1.0 SpOx1.1_006190 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J09 compound treatment -0.0055 0.237 0.88 -0.014 0.229 0.85 1.2181 0.9999 SpOx1.1_006191 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J10 compound treatment -0.0015 0.241 0.89 -0.028 0.215 0.79 1.1918 0.9984 SpOx1.1_006192 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J11 compound treatment -5.0E-4 0.242 0.89 -0.016 0.227 0.84 1.226 0.9995 SpOx1.1_006193 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J12 compound treatment -5.0E-4 0.242 0.89 -0.016 0.226 0.84 1.2257 0.9995 SpOx1.1_006194 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J13 compound treatment -0.0075 0.235 0.87 -0.037 0.205 0.76 1.1525 0.9978 SpOx1.1_006195 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J14 compound treatment -0.0045 0.238 0.88 -0.023 0.22 0.81 1.197 0.9992 SpOx1.1_006196 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J15 compound treatment -0.0165 0.226 0.84 0.0 0.243 0.9 1.226 0.9993 SpOx1.1_006197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J16 compound treatment -0.0125 0.23 0.85 -0.026 0.217 0.8 1.1684 0.9996 SpOx1.1_006198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J17 compound treatment -0.0175 0.225 0.83 -0.011 0.232 0.86 1.1946 0.9999 SpOx1.1_006199 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J18 compound treatment -0.0055 0.237 0.88 -0.014 0.229 0.85 1.2181 0.9999 SpOx1.1_006200 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J19 compound treatment 0.0035 0.246 0.91 0.003 0.246 0.91 1.2861 1.0 SpOx1.1_006201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J20 compound treatment -0.0025 0.24 0.89 -0.002 0.241 0.89 1.2574 1.0 SpOx1.1_006202 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J21 compound treatment 0.0025 0.245 0.91 -0.012 0.23 0.85 1.2441 0.9996 2143288 SpOx1.1_006203 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J22 compound treatment -0.0185 0.224 0.83 -0.019 0.224 0.83 1.171 1.0 SpOx1.1_006204 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J23 mock treatment -0.0135 0.229 0.85 -0.006 0.237 0.88 1.2181 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 J24 mock treatment -0.4796 -0.237 -0.88 -0.4807 -0.238 -0.88 -1.2444 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K01 compound treatment -0.0075 0.235 0.87 0.011 0.254 0.94 1.2783 0.9992 SpOx1.1_006205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K02 compound treatment -0.0185 0.224 0.83 -0.008 0.235 0.87 1.1997 0.9997 SpOx1.1_006206 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K03 compound treatment -0.0255 0.217 0.8 -0.005 0.238 0.88 1.1893 0.9989 SpOx1.1_006207 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K04 compound treatment -0.0165 0.226 0.84 -0.019 0.224 0.83 1.1762 1.0 SpOx1.1_006208 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K05 compound treatment -0.0065 0.236 0.87 -0.004 0.239 0.88 1.2416 1.0 SpOx1.1_006209 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K06 compound treatment -5.0E-4 0.242 0.89 0.005 0.248 0.92 1.2808 0.9999 SpOx1.1_006210 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K07 compound treatment -0.0025 0.24 0.89 -0.034 0.208 0.77 1.1733 0.9976 SpOx1.1_006211 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K08 compound treatment 5.0E-4 0.243 0.9 -0.013 0.23 0.85 1.2363 0.9996 2144736 SpOx1.1_006212 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K09 compound treatment -0.0015 0.241 0.89 -0.015 0.228 0.84 1.2259 0.9996 SpOx1.1_006213 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K10 compound treatment 0.0045 0.247 0.91 -0.006 0.237 0.88 1.2651 0.9998 SpOx1.1_006214 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K11 compound treatment -0.0045 0.238 0.88 -0.007 0.236 0.87 1.239 1.0 SpOx1.1_006215 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K12 compound treatment -0.0055 0.237 0.88 -0.011 0.232 0.86 1.2259 0.9999 SpOx1.1_006216 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K13 compound treatment -0.0055 0.237 0.88 -0.041 0.201 0.75 1.1472 0.9968 SpOx1.1_006217 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K14 compound treatment -0.0025 0.24 0.89 -0.017 0.226 0.84 1.2181 0.9996 SpOx1.1_006218 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K15 compound treatment 0.0025 0.245 0.91 0.005 0.247 0.92 1.2887 1.0 SpOx1.1_006219 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K16 compound treatment 0.0035 0.246 0.91 -0.004 0.239 0.88 1.2677 0.9999 SpOx1.1_006220 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K17 compound treatment -0.0115 0.231 0.85 -0.022 0.22 0.82 1.1813 0.9998 SpOx1.1_006221 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K18 compound treatment -0.0185 0.224 0.83 -0.008 0.235 0.87 1.1998 0.9997 SpOx1.1_006222 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K19 compound treatment -0.0235 0.219 0.81 -0.017 0.225 0.84 1.1631 0.9999 SpOx1.1_006223 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K20 compound treatment -0.0065 0.236 0.87 -0.027 0.215 0.8 1.1813 0.999 SpOx1.1_006224 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K21 compound treatment -0.0295 0.213 0.79 -0.034 0.209 0.77 1.1029 1.0 SpOx1.1_006225 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K22 compound treatment -0.0035 0.239 0.88 -0.011 0.232 0.86 1.2312 0.9999 SpOx1.1_006226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K23 mock treatment -0.0035 0.239 0.88 -0.006 0.236 0.88 1.2442 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 K24 mock treatment -0.4796 -0.237 -0.88 -0.4807 -0.238 -0.88 -1.2444 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L01 compound treatment -0.0045 0.238 0.88 -0.018 0.225 0.83 1.2102 0.9996 SpOx1.1_006227 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L02 compound treatment 0.0025 0.245 0.91 0.003 0.246 0.91 1.2835 1.0 SpOx1.1_006228 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L03 compound treatment -5.0E-4 0.242 0.89 -0.001 0.242 0.89 1.2651 1.0 SpOx1.1_006229 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L04 compound treatment 5.0E-4 0.243 0.9 -0.003 0.24 0.89 1.2625 1.0 SpOx1.1_006230 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L05 compound treatment -0.0115 0.231 0.85 -0.012 0.231 0.85 1.2075 1.0 SpOx1.1_006231 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L06 compound treatment -0.0265 0.216 0.8 -0.018 0.225 0.83 1.1526 0.9998 SpOx1.1_006232 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L07 compound treatment -0.0045 0.238 0.88 -0.002 0.241 0.89 1.252 1.0 SpOx1.1_006233 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L08 compound treatment -0.0075 0.235 0.87 -0.006 0.237 0.88 1.2337 1.0 SpOx1.1_006234 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L09 compound treatment 0.0135 0.256 0.95 0.012 0.254 0.94 1.3357 1.0 SpOx1.1_006235 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L10 compound treatment 0.0175 0.26 0.96 -0.019 0.223 0.83 1.2649 0.9973 SpOx1.1_006236 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L11 compound treatment 0.0165 0.259 0.96 -0.003 0.24 0.89 1.3043 0.9993 SpOx1.1_006237 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L12 compound treatment 0.0035 0.246 0.91 -0.003 0.24 0.89 1.2703 0.9999 2142568 SpOx1.1_006238 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4cccc(OCCO)c4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCn8nnc9ccccc89)ccc17)c%10ccccc%10 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L13 compound treatment 0.0065 0.249 0.92 0.0 0.243 0.9 1.2861 0.9999 SpOx1.1_006239 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L14 compound treatment -0.0055 0.237 0.88 -0.009 0.234 0.87 1.2311 1.0 SpOx1.1_006240 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L15 compound treatment 0.0035 0.246 0.91 0.01 0.252 0.94 1.3043 0.9999 SpOx1.1_006241 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L16 compound treatment 5.0E-4 0.243 0.9 -0.011 0.232 0.86 1.2416 0.9997 SpOx1.1_006242 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L17 compound treatment 0.0255 0.268 0.99 0.001 0.244 0.9 1.3383 0.9989 SpOx1.1_006243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L18 compound treatment 5.0E-4 0.243 0.9 0.01 0.253 0.94 1.2966 0.9998 SpOx1.1_006244 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L19 compound treatment 5.0E-4 0.243 0.9 -0.014 0.229 0.85 1.2337 0.9996 SpOx1.1_006245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L20 compound treatment 0.0055 0.248 0.92 -0.005 0.238 0.88 1.2703 0.9998 SpOx1.1_006246 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L21 compound treatment 0.0135 0.256 0.95 -0.01 0.233 0.86 1.2782 0.9989 SpOx1.1_006247 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L22 compound treatment -0.0295 0.213 0.79 -0.011 0.232 0.86 1.1631 0.9991 SpOx1.1_006248 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L23 mock treatment 0.0115 0.254 0.94 0.012 0.254 0.94 1.3306 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 L24 mock treatment -0.481 -0.239 -0.88 -0.4817 -0.239 -0.89 -1.2507 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M01 compound treatment -5.0E-4 0.242 0.89 0.013 0.256 0.95 1.3018 0.9996 SpOx1.1_006249 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M02 compound treatment -0.0455 0.197 0.73 -0.023 0.22 0.81 1.0898 0.9985 SpOx1.1_006250 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M03 compound treatment 0.0015 0.244 0.9 0.007 0.25 0.92 1.2913 0.9999 SpOx1.1_006251 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M04 compound treatment 0.0125 0.255 0.94 0.02 0.262 0.97 1.3541 0.9999 SpOx1.1_006252 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M05 compound treatment -0.0055 0.237 0.88 0.01 0.253 0.94 1.2809 0.9995 SpOx1.1_006253 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M06 compound treatment 0.0025 0.245 0.91 0.003 0.246 0.91 1.2835 1.0 SpOx1.1_006254 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M07 compound treatment 5.0E-4 0.243 0.9 0.001 0.244 0.9 1.273 1.0 SpOx1.1_006255 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M08 compound treatment -0.0605 0.182 0.67 -0.065 0.178 0.66 0.9406 0.9999 SpOx1.1_006256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M09 compound treatment -0.0045 0.238 0.88 -0.015 0.228 0.84 1.218 0.9998 SpOx1.1_006257 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M10 compound treatment -0.0125 0.23 0.85 -0.008 0.235 0.87 1.2156 0.9999 SpOx1.1_006258 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M11 compound treatment 0.0045 0.247 0.91 0.011 0.253 0.94 1.3096 0.9999 SpOx1.1_006259 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M12 compound treatment -0.0075 0.235 0.87 -0.01 0.233 0.86 1.2233 1.0 SpOx1.1_006260 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M13 compound treatment -5.0E-4 0.242 0.89 -0.01 0.233 0.86 1.2416 0.9998 SpOx1.1_006261 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M14 compound treatment 5.0E-4 0.243 0.9 -0.011 0.232 0.86 1.2416 0.9997 SpOx1.1_006262 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M15 compound treatment -0.0105 0.232 0.86 -0.011 0.232 0.86 1.2129 1.0 SpOx1.1_006263 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M16 compound treatment -0.0665 0.176 0.65 -0.063 0.18 0.67 0.9301 0.9999 SpOx1.1_006264 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M17 compound treatment 0.0015 0.244 0.9 -0.016 0.227 0.84 1.2311 0.9994 SpOx1.1_006265 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M18 compound treatment 0.0055 0.248 0.92 -0.003 0.24 0.89 1.2756 0.9999 SpOx1.1_006266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M19 compound treatment -0.0235 0.219 0.81 -0.014 0.229 0.85 1.1709 0.9997 SpOx1.1_006267 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M20 compound treatment -5.0E-4 0.242 0.89 -0.016 0.227 0.84 1.2259 0.9995 SpOx1.1_006268 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M21 compound treatment -0.0035 0.239 0.88 -0.002 0.241 0.89 1.2547 1.0 SpOx1.1_006269 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M22 compound treatment -5.0E-4 0.242 0.89 -0.003 0.24 0.89 1.26 1.0 SpOx1.1_006270 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M23 mock treatment -0.0025 0.24 0.89 0.009 0.251 0.93 1.2861 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 M24 mock treatment -0.4816 -0.239 -0.88 -0.4837 -0.241 -0.89 -1.2575 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N01 compound treatment -0.0115 0.231 0.85 -0.029 0.214 0.79 1.1631 0.9993 SpOx1.1_006271 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N02 compound treatment -0.2716 -0.0293 -0.11 -0.033 0.21 0.78 0.4725 0.6028 SpOx1.1_006272 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N03 compound treatment -0.0315 0.211 0.78 -0.003 0.24 0.89 1.1788 0.9979 SpOx1.1_006273 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N04 compound treatment -0.0175 0.225 0.83 -0.014 0.229 0.85 1.1867 1.0 SpOx1.1_006274 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N05 compound treatment -0.0185 0.224 0.83 -0.018 0.225 0.83 1.1735 1.0 SpOx1.1_006275 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N06 compound treatment -0.0165 0.226 0.84 -0.027 0.216 0.8 1.1552 0.9998 SpOx1.1_006276 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N07 compound treatment -0.0285 0.214 0.79 -0.043 0.2 0.74 1.082 0.9994 SpOx1.1_006277 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N08 compound treatment -0.0055 0.237 0.88 -0.046 0.197 0.73 1.1341 0.9958 SpOx1.1_006278 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N09 compound treatment -0.0295 0.213 0.79 -0.048 0.195 0.72 1.0662 0.999 SpOx1.1_006279 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N10 compound treatment -0.0045 0.238 0.88 -0.015 0.228 0.84 1.2181 0.9998 2144720 SpOx1.1_006280 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(Cc8ccc9OCOc9c8)CC7)c%10ccccc1%10)c%11ccccc%11 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N11 compound treatment -0.0195 0.223 0.82 -0.021 0.221 0.82 1.163 1.0 SpOx1.1_006281 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N12 compound treatment -0.0095 0.233 0.86 -0.011 0.232 0.86 1.2154 1.0 SpOx1.1_006282 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N13 compound treatment -0.0215 0.221 0.82 -0.014 0.229 0.85 1.1762 0.9998 SpOx1.1_006283 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N14 compound treatment -0.0075 0.235 0.87 0.0 0.243 0.9 1.2494 0.9999 SpOx1.1_006284 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N15 compound treatment 0.0045 0.247 0.91 -0.035 0.208 0.77 1.1892 0.9964 SpOx1.1_006285 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N16 compound treatment -0.0385 0.204 0.75 -0.053 0.19 0.7 1.0296 0.9994 SpOx1.1_006286 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N17 compound treatment -0.0165 0.226 0.84 -0.017 0.226 0.84 1.1815 1.0 SpOx1.1_006287 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N18 compound treatment -0.0075 0.235 0.87 -0.012 0.231 0.85 1.218 1.0 SpOx1.1_006288 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N19 compound treatment -0.0155 0.227 0.84 -0.026 0.217 0.8 1.1605 0.9998 SpOx1.1_006289 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N20 compound treatment 5.0E-4 0.243 0.9 -0.017 0.226 0.84 1.2259 0.9994 SpOx1.1_006290 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N21 compound treatment -0.0265 0.216 0.8 -0.03 0.213 0.79 1.1212 1.0 SpOx1.1_006291 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N22 compound treatment -0.0065 0.236 0.87 -0.015 0.228 0.84 1.2128 0.9999 SpOx1.1_006292 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N23 mock treatment 5.0E-4 0.243 0.9 0.004 0.246 0.91 1.2808 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 N24 mock treatment -0.4796 -0.237 -0.88 -0.4837 -0.241 -0.89 -1.2523 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O01 compound treatment -0.0876 0.155 0.57 -0.011 0.232 0.86 1.0113 0.9806 SpOx1.1_006293 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O02 compound treatment -0.0095 0.233 0.86 0.003 0.246 0.91 1.2521 0.9996 SpOx1.1_006294 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O03 compound treatment -0.0125 0.23 0.85 0.013 0.256 0.95 1.2704 0.9985 SpOx1.1_006295 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O04 compound treatment -5.0E-4 0.242 0.89 0.002 0.245 0.91 1.273 1.0 SpOx1.1_006296 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O05 compound treatment -0.0145 0.228 0.84 0.004 0.247 0.91 1.2416 0.9992 SpOx1.1_006297 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O06 compound treatment -0.0015 0.241 0.89 0.001 0.244 0.9 1.2678 1.0 SpOx1.1_006298 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O07 compound treatment -0.0275 0.215 0.79 -0.048 0.195 0.72 1.0715 0.9988 SpOx1.1_006299 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O08 compound treatment -0.0125 0.23 0.85 -0.005 0.238 0.88 1.2233 0.9998 SpOx1.1_006300 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O09 compound treatment -0.0045 0.238 0.88 -0.003 0.24 0.89 1.2494 1.0 SpOx1.1_006301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O10 compound treatment -0.0195 0.223 0.82 -0.018 0.225 0.83 1.171 1.0 SpOx1.1_006302 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O11 compound treatment -0.0105 0.232 0.86 -0.002 0.241 0.89 1.2364 0.9998 SpOx1.1_006303 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O12 compound treatment -0.0155 0.227 0.84 -0.003 0.24 0.89 1.2207 0.9996 SpOx1.1_006304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O13 compound treatment 0.0015 0.244 0.9 -0.009 0.234 0.87 1.2495 0.9998 SpOx1.1_006305 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O14 compound treatment -0.0025 0.24 0.89 -0.007 0.236 0.87 1.2442 1.0 SpOx1.1_006306 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O15 compound treatment -0.0095 0.233 0.86 0.001 0.244 0.9 1.2468 0.9997 SpOx1.1_006307 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O16 compound treatment 0.0025 0.245 0.91 -0.02 0.223 0.82 1.2232 0.9989 SpOx1.1_006308 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O17 compound treatment 5.0E-4 0.243 0.9 -0.01 0.233 0.86 1.2442 0.9998 SpOx1.1_006309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O18 compound treatment -0.0205 0.222 0.82 -0.018 0.225 0.83 1.1683 1.0 SpOx1.1_006310 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O19 compound treatment -0.0195 0.223 0.82 -0.027 0.216 0.8 1.1474 0.9999 SpOx1.1_006311 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O20 compound treatment -0.0135 0.229 0.85 -0.002 0.241 0.89 1.2285 0.9997 SpOx1.1_006312 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O21 compound treatment -0.0105 0.232 0.86 -0.002 0.241 0.89 1.2364 0.9998 SpOx1.1_006313 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O22 compound treatment 5.0E-4 0.243 0.9 0.006 0.249 0.92 1.2861 0.9999 SpOx1.1_006314 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O23 mock treatment -0.0045 0.238 0.88 0.014 0.257 0.95 1.2941 0.9992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 O24 mock treatment -0.4806 -0.238 -0.88 -0.4847 -0.242 -0.9 -1.2575 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P01 compound treatment -0.0265 0.216 0.8 -0.031 0.212 0.78 1.1186 1.0 SpOx1.1_006315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P02 compound treatment -0.0115 0.231 0.85 -0.011 0.232 0.86 1.2102 1.0 SpOx1.1_006316 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P03 compound treatment -0.0125 0.23 0.85 -0.024 0.219 0.81 1.1736 0.9997 SpOx1.1_006317 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P04 compound treatment -0.0225 0.22 0.81 -0.025 0.218 0.81 1.1448 1.0 SpOx1.1_006318 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P05 compound treatment -0.0335 0.209 0.77 -0.017 0.226 0.84 1.137 0.9992 SpOx1.1_006319 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P06 compound treatment -0.0285 0.214 0.79 -0.018 0.225 0.83 1.1474 0.9997 SpOx1.1_006320 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P07 compound treatment -0.0245 0.218 0.81 -0.04 0.203 0.75 1.1002 0.9994 SpOx1.1_006321 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P08 compound treatment -0.0175 0.225 0.83 -0.032 0.211 0.78 1.1395 0.9995 SpOx1.1_006322 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P09 compound treatment -0.0265 0.216 0.8 -0.024 0.219 0.81 1.1369 1.0 SpOx1.1_006323 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P10 compound treatment -0.0265 0.216 0.8 -0.031 0.212 0.78 1.1185 1.0 SpOx1.1_006324 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P11 compound treatment -0.0395 0.203 0.75 -0.041 0.202 0.75 1.0584 1.0 SpOx1.1_006325 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P12 compound treatment -0.0225 0.22 0.81 -0.028 0.215 0.79 1.1369 0.9999 SpOx1.1_006326 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P13 compound treatment -0.0305 0.212 0.78 -0.028 0.215 0.79 1.116 1.0 SpOx1.1_006327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P14 compound treatment -0.0205 0.222 0.82 -0.016 0.227 0.84 1.1736 0.9999 SpOx1.1_006328 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P15 compound treatment -0.0105 0.232 0.86 -0.032 0.211 0.78 1.1578 0.9989 SpOx1.1_006329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P16 compound treatment -0.0165 0.226 0.84 -0.026 0.217 0.8 1.1579 0.9998 SpOx1.1_006330 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P17 compound treatment -0.0405 0.202 0.75 -0.03 0.213 0.79 1.0846 0.9996 SpOx1.1_006331 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P18 compound treatment -0.0025 0.24 0.89 -0.036 0.207 0.77 1.1682 0.9973 SpOx1.1_006332 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P19 compound treatment -0.0175 0.225 0.83 -0.031 0.212 0.78 1.1422 0.9996 SpOx1.1_006333 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P20 compound treatment -0.0015 0.241 0.89 -0.022 0.221 0.82 1.2075 0.9991 SpOx1.1_006334 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P21 compound treatment -0.0115 0.231 0.85 -0.034 0.209 0.77 1.15 0.9988 SpOx1.1_006335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P22 compound treatment -0.0265 0.216 0.8 -0.041 0.202 0.75 1.0924 0.9994 SpOx1.1_006336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P23 mock treatment -0.0035 0.239 0.88 -0.006 0.237 0.88 1.2443 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1296 P24 mock treatment -0.4796 -0.237 -0.88 -0.4837 -0.241 -0.89 -1.2523 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A01 compound treatment -0.0891 0.155 0.57 -0.0817 0.16 0.59 0.8263 0.9998 SpOx1.1_006337 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A02 compound treatment -0.0771 0.167 0.62 -0.0767 0.165 0.61 0.8707 1.0 SpOx1.1_006338 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A03 compound treatment -0.0691 0.175 0.65 -0.0667 0.175 0.65 0.9179 1.0 SpOx1.1_006339 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A04 compound treatment -0.0911 0.153 0.57 -0.0957 0.146 0.54 0.7843 0.9998 SpOx1.1_006340 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A05 compound treatment -0.0721 0.172 0.64 -0.0567 0.185 0.69 0.9362 0.9993 SpOx1.1_006341 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A06 compound treatment -0.0831 0.161 0.6 -0.0697 0.172 0.64 0.8734 0.9994 SpOx1.1_006342 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A07 compound treatment -0.0631 0.181 0.67 -0.0597 0.182 0.68 0.9519 1.0 SpOx1.1_006343 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A08 compound treatment -0.0741 0.17 0.63 -0.0747 0.167 0.62 0.8837 1.0 SpOx1.1_006344 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A09 compound treatment -0.0905 0.154 0.57 -0.0889 0.153 0.57 0.8037 1.0 SpOx1.1_006345 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A10 compound treatment -0.0771 0.167 0.62 -0.0717 0.17 0.63 0.8838 0.9999 SpOx1.1_006346 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A11 compound treatment -0.0731 0.171 0.63 -0.0647 0.177 0.66 0.9126 0.9998 SpOx1.1_006347 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A12 compound treatment -0.0731 0.171 0.63 -0.0607 0.181 0.67 0.9231 0.9995 SpOx1.1_006348 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A13 compound treatment -0.0791 0.165 0.61 -0.0757 0.166 0.62 0.8681 1.0 SpOx1.1_006349 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A14 compound treatment -0.0855 0.159 0.59 -0.0787 0.163 0.61 0.8435 0.9999 SpOx1.1_006350 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A15 compound treatment -0.0781 0.166 0.61 -0.0657 0.176 0.65 0.8969 0.9995 SpOx1.1_006351 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A16 compound treatment -0.0771 0.167 0.62 -0.0687 0.173 0.64 0.8917 0.9998 SpOx1.1_006352 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A17 compound treatment -0.0721 0.172 0.64 -0.0687 0.173 0.64 0.9048 1.0 SpOx1.1_006353 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A18 compound treatment -0.0791 0.165 0.61 -0.0727 0.169 0.63 0.876 0.9999 SpOx1.1_006354 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A19 compound treatment -0.0801 0.164 0.61 -0.0777 0.164 0.61 0.8603 1.0 SpOx1.1_006355 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A20 compound treatment -0.0761 0.168 0.62 -0.0717 0.17 0.63 0.8864 1.0 SpOx1.1_006356 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A21 compound treatment -0.0945 0.15 0.55 -0.0959 0.146 0.54 0.7749 0.9999 SpOx1.1_006357 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A22 compound treatment -0.0811 0.163 0.6 -0.0779 0.164 0.61 0.8571 1.0 SpOx1.1_006358 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A23 mock treatment -0.0711 0.173 0.64 -0.0697 0.172 0.64 0.9048 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 A24 mock treatment -0.4836 -0.239 -0.88 -0.4768 -0.235 -0.87 -1.2404 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B01 compound treatment -0.0141 0.23 0.85 -0.0077 0.234 0.87 1.2162 0.9999 SpOx1.1_006359 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B02 compound treatment -0.0011 0.243 0.9 3.0E-4 0.242 0.9 1.2711 1.0 2143744 SpOx1.1_006360 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CCN(C)Cc8ccccc8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B03 compound treatment -0.0031 0.241 0.89 0.0043 0.246 0.91 1.2764 0.9999 SpOx1.1_006361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B04 compound treatment 0.0139 0.258 0.95 0.0183 0.26 0.96 1.3575 1.0 SpOx1.1_006362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B05 compound treatment 0.0059 0.25 0.93 0.0053 0.247 0.92 1.3026 1.0 2143624 SpOx1.1_006363 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CCCO)ccc17)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B06 compound treatment -0.0171 0.227 0.84 -0.0077 0.234 0.87 1.2083 0.9999 2144024 SpOx1.1_006364 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CC8(O)CCCCCC8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B07 compound treatment -0.0021 0.242 0.9 -7.0E-4 0.241 0.89 1.2659 1.0 SpOx1.1_006365 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B08 compound treatment 0.0209 0.265 0.98 0.0283 0.27 1.0 1.4021 0.9999 SpOx1.1_006366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B09 compound treatment -0.0101 0.234 0.87 -0.0047 0.237 0.88 1.2346 1.0 SpOx1.1_006367 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B10 compound treatment 0.0029 0.247 0.91 0.0113 0.253 0.94 1.3104 0.9999 SpOx1.1_006368 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B11 compound treatment -0.0011 0.243 0.9 0.0043 0.246 0.91 1.2817 1.0 SpOx1.1_006369 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B12 compound treatment -0.0031 0.241 0.89 0.0023 0.244 0.91 1.2711 1.0 SpOx1.1_006370 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B13 compound treatment -0.0091 0.235 0.87 -0.0087 0.233 0.87 1.2267 1.0 2144304 SpOx1.1_006371 COC(=O)C(CC#Cc1ccc2N(C(=O)N[C@H](C)c3ccccc3)C(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c2c1)C(=O)OC 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B14 compound treatment 0.0099 0.254 0.94 0.0153 0.257 0.95 1.3392 1.0 SpOx1.1_006372 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B15 compound treatment -0.0141 0.23 0.85 -0.0147 0.227 0.84 1.1979 1.0 SpOx1.1_006373 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B16 compound treatment -0.0011 0.243 0.9 0.0093 0.251 0.93 1.2947 0.9998 SpOx1.1_006374 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B17 compound treatment 0.0129 0.257 0.95 0.0173 0.259 0.96 1.3523 1.0 SpOx1.1_006375 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B18 compound treatment 0.0049 0.249 0.92 0.0133 0.255 0.95 1.3209 0.9999 SpOx1.1_006376 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B19 compound treatment 0.0029 0.247 0.91 0.0133 0.255 0.95 1.3156 0.9998 SpOx1.1_006377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B20 compound treatment -0.0091 0.235 0.87 -0.0017 0.24 0.89 1.245 0.9999 SpOx1.1_006378 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B21 compound treatment 0.0029 0.247 0.91 0.0143 0.256 0.95 1.3183 0.9998 SpOx1.1_006379 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B22 compound treatment -0.0061 0.238 0.88 0.0043 0.246 0.91 1.2685 0.9998 SpOx1.1_006380 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B23 mock treatment 0.0099 0.254 0.94 0.0193 0.261 0.97 1.3497 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 B24 mock treatment -0.4826 -0.238 -0.88 -0.4778 -0.236 -0.87 -1.2404 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C01 compound treatment -0.0381 0.206 0.76 -0.0357 0.206 0.76 1.0801 1.0 SpOx1.1_006381 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C02 compound treatment -0.0161 0.228 0.84 -0.0037 0.238 0.88 1.2214 0.9997 SpOx1.1_006382 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C03 compound treatment -0.0271 0.217 0.8 -0.0257 0.216 0.8 1.1351 1.0 SpOx1.1_006383 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C04 compound treatment -1.0E-4 0.244 0.9 -7.0E-4 0.241 0.89 1.2712 1.0 SpOx1.1_006384 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C05 compound treatment 0.0039 0.248 0.92 0.0043 0.246 0.91 1.2947 1.0 SpOx1.1_006385 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C06 compound treatment -0.0151 0.229 0.85 -0.0117 0.23 0.85 1.2031 1.0 SpOx1.1_006386 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C07 compound treatment -0.0181 0.226 0.84 -0.0137 0.228 0.85 1.1901 1.0 SpOx1.1_006387 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C08 compound treatment -0.0021 0.242 0.9 0.0023 0.244 0.91 1.2738 1.0 SpOx1.1_006388 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C09 compound treatment -0.0111 0.233 0.86 -0.0057 0.236 0.88 1.2292 1.0 SpOx1.1_006389 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C10 compound treatment -0.0121 0.232 0.86 -0.0087 0.233 0.87 1.2189 1.0 SpOx1.1_006390 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C11 compound treatment -0.0181 0.226 0.84 -0.0077 0.234 0.87 1.2057 0.9998 SpOx1.1_006391 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C12 compound treatment -0.0051 0.239 0.88 -0.0027 0.239 0.89 1.2529 1.0 SpOx1.1_006392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C13 compound treatment -0.0261 0.218 0.81 -0.0107 0.231 0.86 1.1769 0.9995 SpOx1.1_006393 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C14 compound treatment -0.0161 0.228 0.84 -0.0097 0.232 0.86 1.2057 0.9999 SpOx1.1_006394 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C15 compound treatment -0.0171 0.227 0.84 -0.0117 0.23 0.85 1.1978 1.0 SpOx1.1_006395 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C16 compound treatment -0.0071 0.237 0.88 0.0053 0.247 0.92 1.2686 0.9998 SpOx1.1_006396 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C17 compound treatment -0.0071 0.237 0.88 -0.0037 0.238 0.88 1.2449 1.0 SpOx1.1_006397 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C18 compound treatment -0.0021 0.242 0.9 0.0083 0.25 0.93 1.2895 0.9998 SpOx1.1_006398 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C19 compound treatment 9.0E-4 0.245 0.91 0.0043 0.246 0.91 1.2869 1.0 SpOx1.1_006399 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C20 compound treatment -0.0141 0.23 0.85 -0.0097 0.232 0.86 1.2109 1.0 SpOx1.1_006400 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C21 compound treatment -0.0111 0.233 0.86 -0.0077 0.234 0.87 1.224 1.0 SpOx1.1_006401 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C22 compound treatment -0.0181 0.226 0.84 -0.0097 0.232 0.86 1.2005 0.9999 SpOx1.1_006402 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C23 mock treatment -0.0211 0.223 0.83 -0.0177 0.224 0.83 1.1717 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 C24 mock treatment -0.4816 -0.237 -0.88 -0.4788 -0.237 -0.88 -1.2404 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D01 compound treatment -0.0111 0.233 0.86 -0.0017 0.24 0.89 1.2397 0.9999 SpOx1.1_006403 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D02 compound treatment -0.0101 0.234 0.87 -0.0017 0.24 0.89 1.2423 0.9999 SpOx1.1_006404 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D03 compound treatment -0.0121 0.232 0.86 -0.0067 0.235 0.87 1.224 1.0 SpOx1.1_006405 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D04 compound treatment -0.0391 0.205 0.76 -0.0277 0.214 0.79 1.0985 0.9997 SpOx1.1_006406 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D05 compound treatment -0.0161 0.228 0.84 -0.0087 0.233 0.87 1.2084 0.9999 SpOx1.1_006407 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D06 compound treatment -0.0121 0.232 0.86 -0.0037 0.238 0.88 1.2319 0.9999 SpOx1.1_006408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D07 compound treatment -0.0181 0.226 0.84 -0.0127 0.229 0.85 1.1927 1.0 SpOx1.1_006409 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D08 compound treatment -0.0041 0.24 0.89 -0.0067 0.235 0.87 1.245 1.0 SpOx1.1_006410 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D09 compound treatment -0.0221 0.222 0.82 -0.0137 0.228 0.85 1.1796 0.9999 2143704 SpOx1.1_006411 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CC8(O)CCCCCC8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D10 compound treatment -0.0181 0.226 0.84 -0.0107 0.231 0.86 1.1978 0.9999 2143768 SpOx1.1_006412 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCN(C)Cc8ccccc8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D11 compound treatment 0.0019 0.246 0.91 0.0133 0.255 0.95 1.313 0.9998 SpOx1.1_006413 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D12 compound treatment -0.0111 0.233 0.86 -0.0057 0.236 0.88 1.2292 1.0 SpOx1.1_006414 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D13 compound treatment -0.0181 0.226 0.84 0.0013 0.243 0.9 1.2293 0.9993 SpOx1.1_006415 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D14 compound treatment -0.0161 0.228 0.84 -0.0097 0.232 0.86 1.2057 0.9999 SpOx1.1_006416 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D15 compound treatment -0.0221 0.222 0.82 -0.0187 0.223 0.83 1.1664 1.0 SpOx1.1_006417 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D16 compound treatment -0.0121 0.232 0.86 -0.0057 0.236 0.88 1.2266 1.0 SpOx1.1_006418 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D17 compound treatment -0.0161 0.228 0.84 -0.0057 0.236 0.88 1.2162 0.9998 SpOx1.1_006419 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D18 compound treatment -0.0161 0.228 0.84 -0.0077 0.234 0.87 1.211 0.9999 SpOx1.1_006420 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D19 compound treatment -0.0271 0.217 0.8 -0.0237 0.218 0.81 1.1403 1.0 SpOx1.1_006421 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D20 compound treatment -0.0051 0.239 0.88 0.0013 0.243 0.9 1.2634 1.0 SpOx1.1_006422 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D21 compound treatment -0.0201 0.224 0.83 -0.0097 0.232 0.86 1.1952 0.9998 SpOx1.1_006423 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D22 compound treatment -0.0061 0.238 0.88 3.0E-4 0.242 0.9 1.258 1.0 SpOx1.1_006424 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D23 mock treatment -0.0101 0.234 0.87 -0.0077 0.234 0.87 1.2266 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 D24 mock treatment -0.4826 -0.238 -0.88 -0.4788 -0.237 -0.88 -1.2431 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E01 compound treatment -0.0071 0.237 0.88 -7.0E-4 0.241 0.89 1.2528 1.0 SpOx1.1_006425 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E02 compound treatment -0.0021 0.242 0.9 0.0063 0.248 0.92 1.2842 0.9999 SpOx1.1_006426 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E03 compound treatment -0.0011 0.243 0.9 0.0023 0.244 0.91 1.2764 1.0 SpOx1.1_006427 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E04 compound treatment 9.0E-4 0.245 0.91 0.0053 0.247 0.92 1.2895 1.0 SpOx1.1_006428 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E05 compound treatment 9.0E-4 0.245 0.91 0.0053 0.247 0.92 1.2895 1.0 SpOx1.1_006429 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E06 compound treatment 0.0119 0.256 0.95 0.0113 0.253 0.94 1.334 1.0 SpOx1.1_006430 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E07 compound treatment 0.0039 0.248 0.92 3.0E-4 0.242 0.9 1.2843 0.9999 SpOx1.1_006431 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E08 compound treatment 9.0E-4 0.245 0.91 0.0073 0.249 0.92 1.2948 1.0 SpOx1.1_006432 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E09 compound treatment 0.0079 0.252 0.93 0.0053 0.247 0.92 1.3078 1.0 SpOx1.1_006433 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E10 compound treatment 0.0099 0.254 0.94 0.0183 0.26 0.96 1.347 0.9999 SpOx1.1_006434 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E11 compound treatment -0.0231 0.221 0.82 -0.0147 0.227 0.84 1.1743 0.9999 SpOx1.1_006435 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E12 compound treatment 9.0E-4 0.245 0.91 0.0133 0.255 0.95 1.3104 0.9998 SpOx1.1_006436 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E13 compound treatment -1.0E-4 0.244 0.9 0.0083 0.25 0.93 1.2948 0.9999 SpOx1.1_006437 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E14 compound treatment -0.0081 0.236 0.87 -0.0017 0.24 0.89 1.2476 1.0 SpOx1.1_006438 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E15 compound treatment 0.0189 0.263 0.97 0.0213 0.263 0.98 1.3785 1.0 SpOx1.1_006439 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E16 compound treatment -0.0051 0.239 0.88 0.0083 0.25 0.93 1.2816 0.9997 SpOx1.1_006440 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E17 compound treatment -0.0081 0.236 0.87 -0.0017 0.24 0.89 1.2476 1.0 SpOx1.1_006441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E18 compound treatment 0.0109 0.255 0.94 0.0203 0.262 0.97 1.355 0.9999 SpOx1.1_006442 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E19 compound treatment -0.0111 0.233 0.86 -0.0087 0.233 0.86 1.2214 1.0 SpOx1.1_006443 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E20 compound treatment 9.0E-4 0.245 0.91 0.0093 0.251 0.93 1.2999 0.9999 SpOx1.1_006444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E21 compound treatment -0.0051 0.239 0.88 3.0E-4 0.242 0.9 1.2607 1.0 SpOx1.1_006445 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E22 compound treatment 0.0149 0.259 0.96 0.0123 0.254 0.94 1.3444 1.0 SpOx1.1_006446 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E23 mock treatment 0.0039 0.248 0.92 0.0023 0.244 0.91 1.2894 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 E24 mock treatment -0.4816 -0.237 -0.88 -0.4798 -0.238 -0.88 -1.2431 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F01 compound treatment -0.0171 0.227 0.84 -0.0117 0.23 0.85 1.1979 1.0 SpOx1.1_006447 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F02 compound treatment -0.0181 0.226 0.84 -0.0207 0.221 0.82 1.1717 1.0 SpOx1.1_006448 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F03 compound treatment -1.0E-4 0.244 0.9 -0.0027 0.239 0.89 1.2659 1.0 SpOx1.1_006449 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F04 compound treatment -0.0201 0.224 0.83 -0.0117 0.23 0.85 1.1901 0.9999 SpOx1.1_006450 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F05 compound treatment 0.0109 0.255 0.94 0.0203 0.262 0.97 1.3549 0.9999 SpOx1.1_006451 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F06 compound treatment -1.0E-4 0.244 0.9 0.0043 0.246 0.91 1.2843 1.0 SpOx1.1_006452 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F07 compound treatment -0.0141 0.23 0.85 -0.0117 0.23 0.85 1.2058 1.0 SpOx1.1_006453 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F08 compound treatment 0.0079 0.252 0.93 0.0073 0.249 0.92 1.3131 1.0 SpOx1.1_006454 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F09 compound treatment -0.0211 0.223 0.83 -0.0157 0.226 0.84 1.1769 1.0 SpOx1.1_006455 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F10 compound treatment 0.0079 0.252 0.93 0.0173 0.259 0.96 1.3392 0.9999 SpOx1.1_006456 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F11 compound treatment -0.0061 0.238 0.88 -7.0E-4 0.241 0.89 1.2554 1.0 SpOx1.1_006457 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F12 compound treatment 0.0019 0.246 0.91 0.0103 0.252 0.94 1.3052 0.9999 SpOx1.1_006458 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F13 compound treatment 0.0109 0.255 0.94 0.0133 0.255 0.95 1.3366 1.0 SpOx1.1_006459 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F14 compound treatment -1.0E-4 0.244 0.9 0.0053 0.247 0.92 1.2868 1.0 SpOx1.1_006460 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F15 compound treatment -0.0071 0.237 0.88 3.0E-4 0.242 0.9 1.2554 0.9999 SpOx1.1_006461 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F16 compound treatment 0.0079 0.252 0.93 0.0193 0.261 0.97 1.3444 0.9998 SpOx1.1_006462 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F17 compound treatment -0.0011 0.243 0.9 0.0053 0.247 0.92 1.2842 1.0 SpOx1.1_006463 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F18 compound treatment -0.0081 0.236 0.87 -0.0047 0.237 0.88 1.2398 1.0 SpOx1.1_006464 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F19 compound treatment 9.0E-4 0.245 0.91 0.0133 0.255 0.95 1.3104 0.9998 SpOx1.1_006465 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F20 compound treatment 0.0079 0.252 0.93 0.0133 0.255 0.95 1.3287 1.0 SpOx1.1_006466 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F21 compound treatment -0.0041 0.24 0.89 0.0063 0.248 0.92 1.279 0.9998 SpOx1.1_006467 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F22 compound treatment -0.0051 0.239 0.88 -7.0E-4 0.241 0.89 1.2581 1.0 SpOx1.1_006468 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F23 mock treatment 0.0119 0.256 0.95 0.0133 0.255 0.95 1.3392 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 F24 mock treatment -0.4836 -0.239 -0.88 -0.4818 -0.24 -0.89 -1.2535 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G01 compound treatment -0.0051 0.239 0.88 0.0023 0.244 0.91 1.266 0.9999 SpOx1.1_006469 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G02 compound treatment -0.0621 0.182 0.67 -0.0507 0.191 0.71 0.9781 0.9997 SpOx1.1_006470 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G03 compound treatment -0.0271 0.217 0.8 -0.0267 0.215 0.8 1.1325 1.0 SpOx1.1_006471 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G04 compound treatment -1.0E-4 0.244 0.9 0.0043 0.246 0.91 1.2842 1.0 SpOx1.1_006472 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G05 compound treatment -0.0211 0.223 0.83 -0.0207 0.221 0.82 1.1639 1.0 SpOx1.1_006473 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G06 compound treatment -0.0191 0.225 0.83 -0.0167 0.225 0.84 1.1796 1.0 SpOx1.1_006474 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G07 compound treatment -1.0E-4 0.244 0.9 -0.0027 0.239 0.89 1.2659 1.0 SpOx1.1_006475 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G08 compound treatment -0.0071 0.237 0.88 -7.0E-4 0.241 0.89 1.2529 1.0 SpOx1.1_006476 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G09 compound treatment -0.0091 0.235 0.87 -0.0047 0.237 0.88 1.2371 1.0 SpOx1.1_006477 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G10 compound treatment -0.0061 0.238 0.88 -0.0017 0.24 0.89 1.2528 1.0 SpOx1.1_006478 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G11 compound treatment -0.0141 0.23 0.85 -0.0027 0.239 0.89 1.2293 0.9998 SpOx1.1_006479 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G12 compound treatment -0.0031 0.241 0.89 -0.0027 0.239 0.89 1.258 1.0 SpOx1.1_006480 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G13 compound treatment -0.0061 0.238 0.88 -0.0067 0.235 0.87 1.2397 1.0 SpOx1.1_006481 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G14 compound treatment -0.0101 0.234 0.87 -0.0087 0.233 0.86 1.224 1.0 SpOx1.1_006482 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G15 compound treatment -0.0031 0.241 0.89 -0.0037 0.238 0.88 1.2554 1.0 2143108 SpOx1.1_006483 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCN(C)Cc8ccccc8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G16 compound treatment -0.0091 0.235 0.87 -0.0077 0.234 0.87 1.2292 1.0 SpOx1.1_006484 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G17 compound treatment -0.0091 0.235 0.87 0.0023 0.244 0.91 1.2555 0.9998 SpOx1.1_006485 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G18 compound treatment -0.0271 0.217 0.8 -0.0187 0.223 0.83 1.1534 0.9999 SpOx1.1_006486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G19 compound treatment -0.0081 0.236 0.87 -0.0057 0.236 0.88 1.2372 1.0 SpOx1.1_006487 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G20 compound treatment -0.0411 0.203 0.75 -0.0377 0.204 0.76 1.067 1.0 2141944 SpOx1.1_006488 COc1ccc(C#Cc2ccc3N(C(=O)N[C@H](C)c4ccccc4)C(=O)[C@@]5([C@H]([C@H]6N([C@H]5c7ccc(OCCO)cc7)[C@@H]([C@@H](OC6=O)c8ccccc8)c9ccccc9)C(=O)O)c3c2)cc1 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G21 compound treatment -0.0121 0.232 0.86 -0.0107 0.231 0.86 1.2136 1.0 SpOx1.1_006489 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G22 compound treatment -0.0161 0.228 0.84 -0.0087 0.233 0.86 1.2083 0.9999 SpOx1.1_006490 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G23 mock treatment -0.0151 0.229 0.85 -0.0127 0.229 0.85 1.2004 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 G24 mock treatment -0.4816 -0.237 -0.88 -0.4808 -0.239 -0.88 -1.2457 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H01 compound treatment -0.0181 0.226 0.84 -0.0137 0.228 0.85 1.1901 1.0 SpOx1.1_006491 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H02 compound treatment -0.0311 0.213 0.79 -0.0257 0.216 0.8 1.1246 1.0 SpOx1.1_006492 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H03 compound treatment -0.0221 0.222 0.82 -0.0207 0.221 0.82 1.1613 1.0 SpOx1.1_006493 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H04 compound treatment -0.0181 0.226 0.84 -0.0167 0.225 0.84 1.1822 1.0 SpOx1.1_006494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H05 compound treatment -0.0091 0.235 0.87 -0.0047 0.237 0.88 1.2372 1.0 SpOx1.1_006495 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H06 compound treatment -0.0111 0.233 0.86 -0.0027 0.239 0.89 1.2371 0.9999 SpOx1.1_006496 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H07 compound treatment -0.0161 0.228 0.84 -0.0097 0.232 0.86 1.2058 0.9999 SpOx1.1_006497 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H08 compound treatment -0.0101 0.234 0.87 -0.1048 0.137 0.51 0.9723 0.9679 SpOx1.1_006498 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H09 compound treatment -0.0091 0.235 0.87 -0.0017 0.24 0.89 1.245 0.9999 SpOx1.1_006499 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H10 compound treatment -0.0131 0.231 0.86 0.0013 0.243 0.9 1.2424 0.9996 SpOx1.1_006500 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H11 compound treatment -0.0191 0.225 0.83 -0.0127 0.229 0.85 1.19 0.9999 SpOx1.1_006501 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H12 compound treatment -0.0061 0.238 0.88 3.0E-4 0.242 0.9 1.258 1.0 SpOx1.1_006502 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H13 compound treatment -0.0031 0.241 0.89 -0.0037 0.238 0.88 1.2554 1.0 SpOx1.1_006503 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H14 compound treatment -0.0101 0.234 0.87 -0.0017 0.24 0.89 1.2423 0.9999 SpOx1.1_006504 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H15 compound treatment -0.0091 0.235 0.87 -0.0067 0.235 0.87 1.2319 1.0 SpOx1.1_006505 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H16 compound treatment -0.0081 0.236 0.87 3.0E-4 0.242 0.9 1.2528 0.9999 SpOx1.1_006506 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H17 compound treatment 0.0019 0.246 0.91 0.0073 0.249 0.92 1.2974 1.0 SpOx1.1_006507 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H18 compound treatment -0.0501 0.194 0.72 -0.0407 0.201 0.75 1.0357 0.9998 SpOx1.1_006508 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H19 compound treatment -0.0141 0.23 0.85 -0.0137 0.228 0.85 1.2004 1.0 SpOx1.1_006509 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H20 compound treatment -0.0121 0.232 0.86 -0.0057 0.236 0.88 1.2267 0.9999 SpOx1.1_006510 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H21 compound treatment -0.0151 0.229 0.85 -0.0117 0.23 0.85 1.2031 1.0 SpOx1.1_006511 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H22 compound treatment -0.0161 0.228 0.84 -0.0117 0.23 0.85 1.2005 1.0 SpOx1.1_006512 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H23 mock treatment -0.0121 0.232 0.86 -0.0087 0.233 0.86 1.2188 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 H24 mock treatment -0.4826 -0.238 -0.88 -0.4788 -0.237 -0.88 -1.2431 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I01 compound treatment -0.0021 0.242 0.9 0.0013 0.243 0.9 1.2712 1.0 SpOx1.1_006513 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I02 compound treatment -0.0271 0.217 0.8 -0.0257 0.216 0.8 1.1351 1.0 SpOx1.1_006514 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I03 compound treatment -0.0031 0.241 0.89 -0.0107 0.231 0.86 1.2371 0.9998 SpOx1.1_006515 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I04 compound treatment -0.0371 0.207 0.77 -0.0337 0.208 0.77 1.088 1.0 SpOx1.1_006516 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I05 compound treatment -0.0161 0.228 0.84 -0.0127 0.229 0.85 1.1979 1.0 SpOx1.1_006517 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I06 compound treatment -0.0121 0.232 0.86 -0.0127 0.229 0.85 1.2083 1.0 SpOx1.1_006518 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I07 compound treatment -0.0271 0.217 0.8 -0.0197 0.222 0.82 1.1508 0.9999 SpOx1.1_006519 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I08 compound treatment -0.0181 0.226 0.84 -0.0227 0.219 0.81 1.1665 0.9999 SpOx1.1_006520 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I09 compound treatment 0.0039 0.248 0.92 -7.0E-4 0.241 0.89 1.2816 0.9999 SpOx1.1_006521 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I10 compound treatment -0.0051 0.239 0.88 -0.0057 0.236 0.88 1.2449 1.0 SpOx1.1_006522 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I11 compound treatment -0.0131 0.231 0.86 -0.0057 0.236 0.88 1.224 0.9999 SpOx1.1_006523 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I12 compound treatment -0.0111 0.233 0.86 0.0013 0.243 0.9 1.2476 0.9997 SpOx1.1_006524 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I13 compound treatment 9.0E-4 0.245 0.91 0.0043 0.246 0.91 1.2868 1.0 SpOx1.1_006525 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I14 compound treatment -0.0131 0.231 0.86 -0.0057 0.236 0.88 1.224 0.9999 SpOx1.1_006526 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I15 compound treatment -0.0261 0.218 0.81 -0.0197 0.222 0.82 1.1533 0.9999 SpOx1.1_006527 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I16 compound treatment -0.0251 0.219 0.81 -0.0217 0.22 0.82 1.1507 1.0 SpOx1.1_006528 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I17 compound treatment 9.0E-4 0.245 0.91 0.0053 0.247 0.92 1.2895 1.0 SpOx1.1_006529 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I18 compound treatment -0.0081 0.236 0.87 -0.0057 0.236 0.88 1.2372 1.0 SpOx1.1_006530 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I19 compound treatment -0.0151 0.229 0.85 -0.0207 0.221 0.82 1.1796 0.9999 SpOx1.1_006531 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I20 compound treatment -0.0091 0.235 0.87 -0.0107 0.231 0.86 1.2215 1.0 SpOx1.1_006532 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I21 compound treatment 0.0049 0.249 0.92 0.0033 0.245 0.91 1.2947 1.0 SpOx1.1_006533 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I22 compound treatment -0.0051 0.239 0.88 -0.0037 0.238 0.88 1.2502 1.0 SpOx1.1_006534 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I23 mock treatment 0.0289 0.273 1.01 0.0073 0.249 0.92 1.3679 0.999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 I24 mock treatment -0.4816 -0.237 -0.88 -0.4788 -0.237 -0.88 -1.2404 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J01 compound treatment -0.0021 0.242 0.9 -0.0147 0.227 0.84 1.2293 0.9995 SpOx1.1_006535 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J02 compound treatment -0.0481 0.196 0.73 -0.0517 0.19 0.71 1.0121 0.9999 SpOx1.1_006536 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J03 compound treatment -0.0281 0.216 0.8 -0.0257 0.216 0.8 1.1325 1.0 SpOx1.1_006537 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J04 compound treatment -0.0171 0.227 0.84 -0.0077 0.234 0.87 1.2084 0.9999 SpOx1.1_006538 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J05 compound treatment -0.0201 0.224 0.83 -0.0077 0.234 0.87 1.2005 0.9997 SpOx1.1_006539 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J06 compound treatment -0.0171 0.227 0.84 -0.0097 0.232 0.86 1.2031 0.9999 SpOx1.1_006540 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J07 compound treatment -0.0221 0.222 0.82 -0.0117 0.23 0.85 1.1848 0.9998 SpOx1.1_006541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J08 compound treatment -0.0181 0.226 0.84 -0.0047 0.237 0.88 1.2136 0.9997 SpOx1.1_006542 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J09 compound treatment -0.0181 0.226 0.84 -0.0127 0.229 0.85 1.1927 1.0 SpOx1.1_006543 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J10 compound treatment -0.0211 0.223 0.83 -0.0117 0.23 0.85 1.1874 0.9999 SpOx1.1_006544 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J11 compound treatment -0.0121 0.232 0.86 -0.0017 0.24 0.89 1.2371 0.9998 SpOx1.1_006545 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J12 compound treatment -0.0141 0.23 0.85 -0.0037 0.238 0.88 1.2266 0.9998 SpOx1.1_006546 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J13 compound treatment -0.0351 0.209 0.77 -0.0257 0.216 0.8 1.1141 0.9998 SpOx1.1_006547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J14 compound treatment -0.0191 0.225 0.83 -0.0077 0.234 0.87 1.2031 0.9998 SpOx1.1_006548 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J15 compound treatment -0.0081 0.236 0.87 0.0033 0.245 0.91 1.2607 0.9998 SpOx1.1_006549 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J16 compound treatment -0.0141 0.23 0.85 -0.0077 0.234 0.87 1.2162 0.9999 SpOx1.1_006550 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J17 compound treatment -0.0061 0.238 0.88 0.0013 0.243 0.9 1.2607 0.9999 SpOx1.1_006551 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J18 compound treatment -0.0201 0.224 0.83 -0.0067 0.235 0.87 1.2032 0.9997 SpOx1.1_006552 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J19 compound treatment -1.0E-4 0.244 0.9 -0.0037 0.238 0.88 1.2633 0.9999 SpOx1.1_006553 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J20 compound treatment -0.0021 0.242 0.9 0.0063 0.248 0.92 1.2843 0.9999 SpOx1.1_006554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J21 compound treatment -0.0181 0.226 0.84 -0.0017 0.24 0.89 1.2215 0.9995 SpOx1.1_006555 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J22 compound treatment -0.0071 0.237 0.88 -0.0027 0.239 0.89 1.2476 1.0 SpOx1.1_006556 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J23 mock treatment -0.0091 0.235 0.87 -0.0057 0.236 0.88 1.2345 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 J24 mock treatment -0.4836 -0.239 -0.88 -0.4808 -0.239 -0.88 -1.2509 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K01 compound treatment 0.0039 0.248 0.92 0.0043 0.246 0.91 1.2947 1.0 SpOx1.1_006557 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K02 compound treatment -0.0251 0.219 0.81 -0.0207 0.221 0.82 1.1534 1.0 SpOx1.1_006558 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K03 compound treatment -0.0261 0.218 0.81 -0.0277 0.214 0.79 1.1325 1.0 SpOx1.1_006559 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K04 compound treatment -0.0181 0.226 0.84 -0.0097 0.232 0.86 1.2005 0.9999 SpOx1.1_006560 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K05 compound treatment -0.0181 0.226 0.84 -0.0237 0.218 0.81 1.1639 0.9999 SpOx1.1_006561 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K06 compound treatment -0.0211 0.223 0.83 -0.0227 0.219 0.81 1.1586 1.0 SpOx1.1_006562 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K07 compound treatment -0.0461 0.198 0.73 -0.0357 0.206 0.76 1.0591 0.9998 SpOx1.1_006563 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K08 compound treatment -0.0301 0.214 0.79 -0.0207 0.221 0.82 1.1403 0.9998 SpOx1.1_006564 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K09 compound treatment -0.0171 0.227 0.84 -0.0127 0.229 0.85 1.1952 1.0 SpOx1.1_006565 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K10 compound treatment -0.0041 0.24 0.89 0.0033 0.245 0.91 1.2711 0.9999 SpOx1.1_006566 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K11 compound treatment -0.0121 0.232 0.86 -0.0047 0.237 0.88 1.2293 0.9999 SpOx1.1_006567 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K12 compound treatment -0.0071 0.237 0.88 -0.0027 0.239 0.89 1.2476 1.0 SpOx1.1_006568 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K13 compound treatment -0.0371 0.207 0.77 -0.0307 0.211 0.78 1.0958 0.9999 SpOx1.1_006569 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K14 compound treatment -0.0041 0.24 0.89 0.0023 0.244 0.91 1.2685 1.0 SpOx1.1_006570 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K15 compound treatment 0.0039 0.248 0.92 0.0013 0.243 0.9 1.2868 1.0 SpOx1.1_006571 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K16 compound treatment -0.0051 0.239 0.88 0.0023 0.244 0.91 1.2659 0.9999 SpOx1.1_006572 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K17 compound treatment -0.0211 0.223 0.83 -0.0207 0.221 0.82 1.1638 1.0 SpOx1.1_006573 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K18 compound treatment -0.0031 0.241 0.89 0.0023 0.244 0.91 1.2711 1.0 SpOx1.1_006574 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K19 compound treatment -0.0111 0.233 0.86 -0.0167 0.225 0.84 1.2005 0.9999 SpOx1.1_006575 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K20 compound treatment -0.0231 0.221 0.82 -0.0197 0.222 0.82 1.1612 1.0 SpOx1.1_006576 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K21 compound treatment -0.0141 0.23 0.85 -0.0117 0.23 0.85 1.2058 1.0 SpOx1.1_006577 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K22 compound treatment -0.0031 0.241 0.89 -0.0127 0.229 0.85 1.2319 0.9997 SpOx1.1_006578 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K23 mock treatment -0.0111 0.233 0.86 -0.0067 0.235 0.87 1.2266 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 K24 mock treatment -0.4816 -0.237 -0.88 -0.4798 -0.238 -0.88 -1.2431 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L01 compound treatment -0.0211 0.223 0.83 -0.0857 0.156 0.58 0.9936 0.9851 SpOx1.1_006579 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L02 compound treatment -0.0051 0.239 0.88 -0.0107 0.231 0.86 1.2319 0.9999 SpOx1.1_006580 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L03 compound treatment -0.0721 0.172 0.64 -0.0847 0.157 0.58 0.8628 0.999 SpOx1.1_006581 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L04 compound treatment -0.0081 0.236 0.87 0.0013 0.243 0.9 1.2555 0.9999 SpOx1.1_006582 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L05 compound treatment -0.0271 0.217 0.8 -0.0237 0.218 0.81 1.1403 1.0 SpOx1.1_006583 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L06 compound treatment 0.0019 0.246 0.91 0.0073 0.249 0.92 1.2974 1.0 SpOx1.1_006584 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L07 compound treatment -0.0121 0.232 0.86 0.0023 0.244 0.91 1.2477 0.9996 SpOx1.1_006585 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L08 compound treatment -0.0091 0.235 0.87 0.0023 0.244 0.91 1.2555 0.9998 SpOx1.1_006586 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L09 compound treatment 0.0019 0.246 0.91 0.0113 0.253 0.94 1.3079 0.9999 SpOx1.1_006587 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L10 compound treatment -0.0141 0.23 0.85 -0.0057 0.236 0.88 1.2214 0.9999 SpOx1.1_006588 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L11 compound treatment -0.0041 0.24 0.89 0.0023 0.244 0.91 1.2686 1.0 SpOx1.1_006589 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L12 compound treatment -0.0011 0.243 0.9 0.0143 0.256 0.95 1.3078 0.9996 2142296 SpOx1.1_006590 COc1ccc(C#Cc2ccc3N(C(=O)N[C@H](C)c4ccccc4)C(=O)[C@@]5([C@H]([C@H]6N([C@H]5c7cccc(OCCO)c7)[C@@H]([C@@H](OC6=O)c8ccccc8)c9ccccc9)C(=O)N%10CCN(CC%10)c%11ncccn%11)c3c2)cc1 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L13 compound treatment -0.0091 0.235 0.87 0.0073 0.249 0.92 1.2685 0.9995 SpOx1.1_006591 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L14 compound treatment -0.0041 0.24 0.89 0.0103 0.252 0.94 1.2895 0.9997 SpOx1.1_006592 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L15 compound treatment -0.0041 0.24 0.89 0.0183 0.26 0.96 1.3104 0.9991 SpOx1.1_006593 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L16 compound treatment -0.0161 0.228 0.84 -0.0077 0.234 0.87 1.211 0.9999 SpOx1.1_006594 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L17 compound treatment 9.0E-4 0.245 0.91 0.0083 0.25 0.93 1.2974 0.9999 SpOx1.1_006595 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L18 compound treatment 0.0029 0.247 0.91 0.0163 0.258 0.96 1.3236 0.9997 SpOx1.1_006596 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L19 compound treatment 0.0029 0.247 0.91 -0.0017 0.24 0.89 1.2763 0.9999 SpOx1.1_006597 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L20 compound treatment 0.0059 0.25 0.93 0.0043 0.246 0.91 1.2999 1.0 SpOx1.1_006598 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L21 compound treatment -0.0131 0.231 0.86 -0.0107 0.231 0.86 1.211 1.0 SpOx1.1_006599 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L22 compound treatment 0.0029 0.247 0.91 -7.0E-4 0.241 0.89 1.279 0.9999 SpOx1.1_006600 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L23 mock treatment 0.0139 0.258 0.95 0.0133 0.255 0.95 1.3444 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 L24 mock treatment -0.485 -0.241 -0.89 -0.4808 -0.239 -0.88 -1.2546 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M01 compound treatment 0.0099 0.254 0.94 0.0183 0.26 0.97 1.3471 0.9999 SpOx1.1_006601 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M02 compound treatment -0.0261 0.218 0.81 -0.0147 0.227 0.84 1.1665 0.9998 SpOx1.1_006602 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M03 compound treatment -0.0121 0.232 0.86 -0.0187 0.223 0.83 1.1927 0.9998 SpOx1.1_006603 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M04 compound treatment 0.0039 0.248 0.92 0.0113 0.253 0.94 1.313 0.9999 SpOx1.1_006604 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M05 compound treatment -0.0071 0.237 0.88 -0.0107 0.231 0.86 1.2267 0.9999 SpOx1.1_006605 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M06 compound treatment -0.0071 0.237 0.88 -0.0037 0.238 0.88 1.245 1.0 SpOx1.1_006606 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M07 compound treatment -0.0121 0.232 0.86 -0.0077 0.234 0.87 1.2215 1.0 SpOx1.1_006607 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M08 compound treatment -0.0181 0.226 0.84 -0.0167 0.225 0.84 1.1822 1.0 SpOx1.1_006608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M09 compound treatment -0.0111 0.233 0.86 -0.0077 0.234 0.87 1.2241 1.0 SpOx1.1_006609 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M10 compound treatment -0.0261 0.218 0.81 -0.0087 0.233 0.86 1.1822 0.9994 SpOx1.1_006610 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M11 compound treatment 9.0E-4 0.245 0.91 0.0063 0.248 0.92 1.2921 1.0 SpOx1.1_006611 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M12 compound treatment -0.0101 0.234 0.87 -7.0E-4 0.241 0.89 1.245 0.9999 SpOx1.1_006612 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M13 compound treatment -0.0101 0.234 0.87 -0.0057 0.236 0.88 1.2319 1.0 SpOx1.1_006613 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M14 compound treatment -1.0E-4 0.244 0.9 0.0193 0.261 0.97 1.3235 0.9994 SpOx1.1_006614 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M15 compound treatment -0.0131 0.231 0.86 -0.0027 0.239 0.89 1.2319 0.9998 SpOx1.1_006615 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M16 compound treatment -0.0031 0.241 0.89 0.0043 0.246 0.91 1.2764 0.9999 SpOx1.1_006616 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M17 compound treatment -0.0141 0.23 0.85 -0.0037 0.238 0.88 1.2266 0.9998 SpOx1.1_006617 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M18 compound treatment -0.0071 0.237 0.88 0.0073 0.249 0.92 1.2738 0.9997 SpOx1.1_006618 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M19 compound treatment 0.0049 0.249 0.92 3.0E-4 0.242 0.9 1.2869 0.9999 SpOx1.1_006619 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M20 compound treatment -0.0121 0.232 0.86 -0.0117 0.23 0.85 1.211 1.0 SpOx1.1_006620 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M21 compound treatment -0.0061 0.238 0.88 0.0013 0.243 0.9 1.2607 0.9999 SpOx1.1_006621 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M22 compound treatment 0.0019 0.246 0.91 0.0103 0.252 0.94 1.3052 0.9999 SpOx1.1_006622 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M23 mock treatment 0.0049 0.249 0.92 0.0043 0.246 0.91 1.2974 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 M24 mock treatment -0.4826 -0.238 -0.88 -0.4818 -0.24 -0.89 -1.2509 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N01 compound treatment -0.0311 0.213 0.79 -0.0187 0.223 0.83 1.1429 0.9997 SpOx1.1_006623 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N02 compound treatment -0.0281 0.216 0.8 -0.0207 0.221 0.82 1.1456 0.9999 SpOx1.1_006624 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N03 compound treatment -0.0221 0.222 0.82 -0.0057 0.236 0.88 1.2006 0.9995 SpOx1.1_006625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N04 compound treatment -0.0271 0.217 0.8 -0.0127 0.229 0.85 1.1691 0.9996 SpOx1.1_006626 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N05 compound treatment -0.0241 0.22 0.81 -0.0177 0.224 0.83 1.1639 0.9999 SpOx1.1_006627 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N06 compound treatment -0.0291 0.215 0.8 -0.0227 0.219 0.81 1.1377 0.9999 SpOx1.1_006628 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N07 compound treatment -0.0361 0.208 0.77 -0.0347 0.207 0.77 1.0879 1.0 SpOx1.1_006629 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N08 compound treatment -0.0481 0.196 0.73 -0.0377 0.204 0.76 1.0487 0.9998 SpOx1.1_006630 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N09 compound treatment -0.0451 0.199 0.74 -0.0377 0.204 0.76 1.0565 0.9999 SpOx1.1_006631 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N10 compound treatment -0.0171 0.227 0.84 -0.0087 0.233 0.87 1.2058 0.9999 SpOx1.1_006632 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N11 compound treatment -0.0331 0.211 0.78 -0.0127 0.229 0.85 1.1534 0.9991 SpOx1.1_006633 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N12 compound treatment -0.0061 0.238 0.88 0.0093 0.251 0.93 1.2816 0.9996 SpOx1.1_006634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N13 compound treatment -0.0191 0.225 0.83 0.0043 0.246 0.91 1.2345 0.9989 SpOx1.1_006635 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N14 compound treatment -0.0031 0.241 0.89 0.0063 0.248 0.92 1.2816 0.9999 SpOx1.1_006636 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N15 compound treatment -0.0311 0.213 0.79 -0.0107 0.231 0.86 1.1639 0.9991 SpOx1.1_006637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N16 compound treatment -0.0191 0.225 0.83 -0.0167 0.225 0.84 1.1796 1.0 SpOx1.1_006638 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N17 compound treatment -0.0271 0.217 0.8 -0.0217 0.22 0.82 1.1456 1.0 SpOx1.1_006639 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N18 compound treatment -0.0121 0.232 0.86 -0.0027 0.239 0.89 1.2346 0.9999 SpOx1.1_006640 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N19 compound treatment -0.0281 0.216 0.8 -0.0247 0.217 0.81 1.1351 1.0 SpOx1.1_006641 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N20 compound treatment -0.0301 0.214 0.79 -0.0317 0.21 0.78 1.1115 1.0 SpOx1.1_006642 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N21 compound treatment 0.0069 0.251 0.93 0.0133 0.255 0.95 1.3262 1.0 SpOx1.1_006643 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N22 compound treatment -0.0051 0.239 0.88 -0.0017 0.24 0.89 1.2555 1.0 SpOx1.1_006644 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N23 mock treatment 0.0029 0.247 0.91 0.0073 0.249 0.92 1.2999 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 N24 mock treatment -0.4836 -0.239 -0.88 -0.4828 -0.241 -0.89 -1.2562 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O01 compound treatment -0.0261 0.218 0.81 -0.0217 0.22 0.82 1.1482 1.0 SpOx1.1_006645 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O02 compound treatment -1.0E-4 0.244 0.9 0.0023 0.244 0.91 1.279 1.0 SpOx1.1_006646 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O03 compound treatment -0.0171 0.227 0.84 -0.0217 0.22 0.82 1.1717 0.9999 SpOx1.1_006647 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O04 compound treatment -0.0011 0.243 0.9 3.0E-4 0.242 0.9 1.2712 1.0 SpOx1.1_006648 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O05 compound treatment -0.0041 0.24 0.89 -0.0077 0.234 0.87 1.2424 0.9999 SpOx1.1_006649 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O06 compound treatment -0.0111 0.233 0.86 -0.0097 0.232 0.86 1.2188 1.0 SpOx1.1_006650 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O07 compound treatment -0.0281 0.216 0.8 -0.0267 0.215 0.8 1.1299 1.0 SpOx1.1_006651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O08 compound treatment -0.0041 0.24 0.89 -0.0037 0.238 0.88 1.2529 1.0 SpOx1.1_006652 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O09 compound treatment -0.0141 0.23 0.85 -0.0137 0.228 0.85 1.2005 1.0 SpOx1.1_006653 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O10 compound treatment -0.0221 0.222 0.82 -0.0147 0.227 0.84 1.177 0.9999 SpOx1.1_006654 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O11 compound treatment -0.0241 0.22 0.81 -0.0087 0.233 0.87 1.1875 0.9995 SpOx1.1_006655 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O12 compound treatment -0.0121 0.232 0.86 -0.0057 0.236 0.88 1.2267 0.9999 SpOx1.1_006656 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O13 compound treatment -0.0641 0.18 0.67 -0.0067 0.235 0.87 1.0881 0.9912 SpOx1.1_006657 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O14 compound treatment -0.0111 0.233 0.86 -7.0E-4 0.241 0.89 1.2423 0.9998 SpOx1.1_006658 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O15 compound treatment 0.0129 0.257 0.95 0.0203 0.262 0.97 1.3602 0.9999 SpOx1.1_006659 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O16 compound treatment -0.0201 0.224 0.83 -0.0137 0.228 0.85 1.1848 0.9999 SpOx1.1_006660 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O17 compound treatment -0.0181 0.226 0.84 -0.0167 0.225 0.84 1.1822 1.0 SpOx1.1_006661 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O18 compound treatment -0.0051 0.239 0.88 3.0E-4 0.242 0.9 1.2607 1.0 SpOx1.1_006662 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O19 compound treatment -0.0201 0.224 0.83 -0.0307 0.211 0.78 1.1403 0.9996 SpOx1.1_006663 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O20 compound treatment -0.0221 0.222 0.82 -0.0187 0.223 0.83 1.1665 1.0 SpOx1.1_006664 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O21 compound treatment 0.0079 0.252 0.93 0.0243 0.266 0.99 1.3576 0.9996 SpOx1.1_006665 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O22 compound treatment 0.0109 0.255 0.94 0.0093 0.251 0.93 1.3262 1.0 SpOx1.1_006666 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O23 mock treatment 0.0129 0.257 0.95 0.0183 0.26 0.97 1.355 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 O24 mock treatment -0.4836 -0.239 -0.88 -0.4798 -0.238 -0.88 -1.2483 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P01 compound treatment -0.0351 0.209 0.77 -0.0397 0.202 0.75 1.0774 0.9999 SpOx1.1_006667 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P02 compound treatment -0.0201 0.224 0.83 -0.0157 0.226 0.84 1.1796 1.0 SpOx1.1_006668 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P03 compound treatment -0.0281 0.216 0.8 -0.0197 0.222 0.82 1.1481 0.9999 SpOx1.1_006669 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P04 compound treatment -0.0261 0.218 0.81 -0.0207 0.221 0.82 1.1508 1.0 SpOx1.1_006670 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P05 compound treatment -0.0361 0.208 0.77 -0.0277 0.214 0.79 1.1063 0.9999 SpOx1.1_006671 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P06 compound treatment -0.0141 0.23 0.85 -0.0067 0.235 0.87 1.2189 0.9999 SpOx1.1_006672 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P07 compound treatment -0.0381 0.206 0.76 -0.0317 0.21 0.78 1.0906 0.9999 SpOx1.1_006673 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P08 compound treatment -0.0331 0.211 0.78 -0.0177 0.224 0.83 1.1404 0.9995 SpOx1.1_006674 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P09 compound treatment -0.0261 0.218 0.81 -0.0157 0.226 0.84 1.1638 0.9998 SpOx1.1_006675 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P10 compound treatment -0.0361 0.208 0.77 -0.0277 0.214 0.79 1.1063 0.9999 SpOx1.1_006676 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P11 compound treatment -0.0401 0.204 0.76 -0.0267 0.215 0.8 1.0984 0.9996 SpOx1.1_006677 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P12 compound treatment -0.0281 0.216 0.8 -0.0167 0.225 0.84 1.156 0.9998 SpOx1.1_006678 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P13 compound treatment -0.0571 0.187 0.69 -0.0417 0.2 0.74 1.0147 0.9994 SpOx1.1_006679 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P14 compound treatment -0.0171 0.227 0.84 -0.0027 0.239 0.89 1.2215 0.9996 SpOx1.1_006680 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P15 compound treatment -0.0271 0.217 0.8 -0.0237 0.218 0.81 1.1403 1.0 SpOx1.1_006681 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P16 compound treatment -0.0201 0.224 0.83 -0.0127 0.229 0.85 1.1874 0.9999 SpOx1.1_006682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P17 compound treatment -0.0271 0.217 0.8 -0.0227 0.219 0.81 1.143 1.0 SpOx1.1_006683 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P18 compound treatment -0.0361 0.208 0.77 -0.0367 0.205 0.76 1.0827 1.0 SpOx1.1_006684 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P19 compound treatment -0.0261 0.218 0.81 -0.0157 0.226 0.84 1.1639 0.9998 SpOx1.1_006685 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P20 compound treatment -0.0141 0.23 0.85 -0.0097 0.232 0.86 1.211 1.0 SpOx1.1_006686 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P21 compound treatment -0.0241 0.22 0.81 -0.0167 0.225 0.84 1.1665 0.9999 SpOx1.1_006687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P22 compound treatment -0.0231 0.221 0.82 -0.0197 0.222 0.82 1.1613 1.0 SpOx1.1_006688 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P23 mock treatment -0.0311 0.213 0.79 -0.0257 0.216 0.8 1.1245 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1297 P24 mock treatment -0.4856 -0.241 -0.89 -0.481 -0.239 -0.89 -1.2567 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A01 compound treatment -0.0668 0.171 0.63 -0.0616 0.175 0.65 0.9052 0.9999 SpOx1.1_006689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A02 compound treatment -0.0618 0.176 0.65 -0.0616 0.175 0.65 0.9184 1.0 SpOx1.1_006690 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A03 compound treatment -0.096 0.142 0.52 -0.0901 0.146 0.54 0.7543 0.9998 SpOx1.1_006691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A04 compound treatment -0.088 0.15 0.55 -0.0881 0.148 0.55 0.7804 1.0 SpOx1.1_006692 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A05 compound treatment -0.0688 0.169 0.62 -0.0666 0.17 0.63 0.887 1.0 SpOx1.1_006693 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A06 compound treatment -0.0418 0.196 0.72 -0.0346 0.202 0.75 1.0414 0.9999 SpOx1.1_006694 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A07 compound treatment -0.097 0.141 0.52 -0.0891 0.147 0.55 0.7543 0.9997 SpOx1.1_006695 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A08 compound treatment -0.0758 0.162 0.6 -0.0726 0.164 0.61 0.8528 1.0 SpOx1.1_006696 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A09 compound treatment -0.0728 0.165 0.61 -0.0646 0.172 0.64 0.8818 0.9998 SpOx1.1_006697 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A10 compound treatment -0.0738 0.164 0.61 -0.0746 0.162 0.6 0.8529 1.0 SpOx1.1_006698 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A11 compound treatment -0.0538 0.184 0.68 -0.0526 0.184 0.68 0.9628 1.0 SpOx1.1_006699 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A12 compound treatment -0.0698 0.168 0.62 -0.0706 0.166 0.61 0.8738 1.0 SpOx1.1_006700 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A13 compound treatment -0.0758 0.162 0.6 -0.0676 0.169 0.63 0.8659 0.9997 SpOx1.1_006701 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A14 compound treatment -0.0748 0.163 0.6 -0.0746 0.162 0.6 0.8503 1.0 SpOx1.1_006702 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A15 compound treatment -0.0688 0.169 0.62 -0.0546 0.182 0.67 0.9184 0.9993 SpOx1.1_006703 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A16 compound treatment -0.0628 0.175 0.65 -0.0616 0.175 0.65 0.9158 1.0 SpOx1.1_006704 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A17 compound treatment -0.0858 0.152 0.56 -0.0806 0.156 0.58 0.8058 0.9999 SpOx1.1_006705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A18 compound treatment -0.0658 0.172 0.64 -0.0626 0.174 0.64 0.9052 1.0 SpOx1.1_006706 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A19 compound treatment -0.0788 0.159 0.59 -0.0736 0.163 0.6 0.8425 0.9999 SpOx1.1_006707 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A20 compound treatment -0.0838 0.154 0.57 -0.0736 0.163 0.6 0.8294 0.9996 SpOx1.1_006708 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A21 compound treatment -0.0758 0.162 0.6 -0.0616 0.175 0.65 0.8818 0.9992 SpOx1.1_006709 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A22 compound treatment -0.0818 0.156 0.58 -0.0746 0.162 0.6 0.8319 0.9998 SpOx1.1_006710 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A23 mock treatment -0.0768 0.161 0.59 -0.0696 0.167 0.62 0.8582 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 A24 mock treatment -0.4688 -0.231 -0.85 -0.4655 -0.229 -0.85 -1.204 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B01 compound treatment -0.0108 0.227 0.84 -0.0076 0.229 0.85 1.1932 1.0 2141444 SpOx1.1_006711 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCCc8ccccn8)c2c1 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B02 compound treatment -0.0038 0.234 0.86 0.0024 0.239 0.89 1.2376 0.9999 SpOx1.1_006712 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B03 compound treatment 0.0022 0.24 0.89 0.0074 0.244 0.9 1.2664 1.0 SpOx1.1_006713 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B04 compound treatment -0.0068 0.231 0.85 -0.0086 0.228 0.84 1.201 1.0 SpOx1.1_006714 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B05 compound treatment 0.0032 0.241 0.89 0.0094 0.246 0.91 1.2743 0.9999 SpOx1.1_006715 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B06 compound treatment -0.0088 0.229 0.85 -0.0086 0.228 0.84 1.1958 1.0 SpOx1.1_006716 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B07 compound treatment -0.0268 0.211 0.78 -0.0236 0.213 0.79 1.1095 1.0 SpOx1.1_006717 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B08 compound treatment 0.0132 0.251 0.93 0.0114 0.248 0.92 1.3057 1.0 SpOx1.1_006718 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B09 compound treatment 0.0042 0.242 0.89 0.0074 0.244 0.9 1.2717 1.0 SpOx1.1_006719 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B10 compound treatment 0.0102 0.248 0.92 0.0074 0.244 0.9 1.2874 1.0 SpOx1.1_006720 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B11 compound treatment 0.0102 0.248 0.92 0.0154 0.252 0.93 1.3083 1.0 SpOx1.1_006721 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B12 compound treatment -0.0038 0.234 0.86 -0.0056 0.231 0.86 1.2168 1.0 SpOx1.1_006722 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B13 compound treatment 0.0142 0.252 0.93 0.0214 0.258 0.96 1.3345 0.9999 SpOx1.1_006723 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B14 compound treatment -0.0088 0.229 0.85 -0.0026 0.234 0.87 1.2115 0.9999 SpOx1.1_006724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B15 compound treatment -0.0198 0.218 0.81 -0.0176 0.219 0.81 1.1436 1.0 SpOx1.1_006725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B16 compound treatment -0.0078 0.23 0.85 -0.0076 0.229 0.85 1.2011 1.0 SpOx1.1_006726 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B17 compound treatment -0.0028 0.235 0.87 0.0024 0.239 0.89 1.2403 1.0 SpOx1.1_006727 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B18 compound treatment 0.0012 0.239 0.88 0.0044 0.241 0.89 1.256 1.0 SpOx1.1_006728 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B19 compound treatment 0.0032 0.241 0.89 0.0064 0.243 0.9 1.2664 1.0 SpOx1.1_006729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B20 compound treatment 0.0032 0.241 0.89 0.0084 0.245 0.91 1.2717 1.0 SpOx1.1_006730 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B21 compound treatment 0.0192 0.257 0.95 0.0234 0.26 0.96 1.3528 1.0 SpOx1.1_006731 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B22 compound treatment -8.0E-4 0.237 0.88 0.0014 0.238 0.88 1.2429 1.0 SpOx1.1_006732 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B23 mock treatment -0.0058 0.232 0.86 -0.0036 0.233 0.86 1.2167 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 B24 mock treatment -0.4688 -0.231 -0.85 -0.4675 -0.231 -0.86 -1.2093 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C01 compound treatment -0.0148 0.223 0.82 -0.0096 0.227 0.84 1.1775 0.9999 SpOx1.1_006733 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C02 compound treatment -0.0208 0.217 0.8 -0.0156 0.221 0.82 1.146 0.9999 SpOx1.1_006734 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C03 compound treatment -0.0098 0.228 0.84 -0.0026 0.234 0.87 1.2089 0.9999 SpOx1.1_006735 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C04 compound treatment -0.0358 0.202 0.75 -0.0356 0.201 0.74 1.0545 1.0 SpOx1.1_006736 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C05 compound treatment -0.0278 0.21 0.78 -0.0236 0.213 0.79 1.1068 1.0 SpOx1.1_006737 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C06 compound treatment 0.0042 0.242 0.89 0.0054 0.242 0.9 1.2664 1.0 SpOx1.1_006738 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C07 compound treatment -0.0098 0.228 0.84 4.0E-4 0.237 0.88 1.2168 0.9998 SpOx1.1_006739 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C08 compound treatment -0.0038 0.234 0.86 -0.0016 0.235 0.87 1.2272 1.0 SpOx1.1_006740 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C09 compound treatment -0.0028 0.235 0.87 0.0054 0.242 0.9 1.2482 0.9999 SpOx1.1_006741 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C10 compound treatment -0.0018 0.236 0.87 -0.0026 0.234 0.87 1.2298 1.0 SpOx1.1_006742 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C11 compound treatment -0.0088 0.229 0.85 -0.0036 0.233 0.86 1.2089 1.0 SpOx1.1_006743 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C12 compound treatment -0.0088 0.229 0.85 -0.0076 0.229 0.85 1.1985 1.0 SpOx1.1_006744 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C13 compound treatment -0.0018 0.236 0.87 0.0024 0.239 0.89 1.2429 1.0 SpOx1.1_006745 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C14 compound treatment -8.0E-4 0.237 0.88 4.0E-4 0.237 0.88 1.2403 1.0 SpOx1.1_006746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C15 compound treatment -0.0158 0.222 0.82 -0.0106 0.226 0.84 1.1723 0.9999 SpOx1.1_006747 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C16 compound treatment -0.0038 0.234 0.86 0.0044 0.241 0.89 1.2429 0.9999 SpOx1.1_006748 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C17 compound treatment 0.0112 0.249 0.92 0.0499 0.286 1.06 1.4014 0.9975 SpOx1.1_006749 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C18 compound treatment -0.0068 0.231 0.85 -0.0016 0.235 0.87 1.2195 1.0 SpOx1.1_006750 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C19 compound treatment 0.0012 0.239 0.88 0.0074 0.244 0.9 1.2638 0.9999 SpOx1.1_006751 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C20 compound treatment -0.0088 0.229 0.85 -0.0086 0.228 0.84 1.1958 1.0 SpOx1.1_006752 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C21 compound treatment 0.0172 0.255 0.94 0.0134 0.25 0.93 1.3213 1.0 SpOx1.1_006753 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C22 compound treatment 0.0032 0.241 0.89 -6.0E-4 0.236 0.87 1.2481 1.0 SpOx1.1_006754 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C23 mock treatment -0.0218 0.216 0.8 -0.0206 0.216 0.8 1.1303 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 C24 mock treatment -0.4698 -0.232 -0.86 -0.4655 -0.229 -0.85 -1.2067 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D01 compound treatment -0.0168 0.221 0.82 -0.0126 0.224 0.83 1.1645 1.0 SpOx1.1_006755 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D02 compound treatment -0.0168 0.221 0.82 -0.0106 0.226 0.84 1.1696 0.9999 SpOx1.1_006756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D03 compound treatment -0.0088 0.229 0.85 -0.0086 0.228 0.84 1.1959 1.0 SpOx1.1_006757 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D04 compound treatment 0.0082 0.246 0.91 0.0124 0.249 0.92 1.2953 1.0 SpOx1.1_006758 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D05 compound treatment -0.0068 0.231 0.85 -6.0E-4 0.236 0.87 1.222 0.9999 SpOx1.1_006759 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D06 compound treatment -0.0128 0.225 0.83 -0.0136 0.223 0.83 1.1723 1.0 SpOx1.1_006760 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D07 compound treatment -0.0168 0.221 0.82 -0.0136 0.223 0.83 1.1619 1.0 SpOx1.1_006761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D08 compound treatment -0.0028 0.235 0.87 -0.0016 0.235 0.87 1.2299 1.0 SpOx1.1_006762 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D09 compound treatment -0.0168 0.221 0.82 -0.0206 0.216 0.8 1.1434 0.9999 SpOx1.1_006763 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D10 compound treatment -0.0228 0.215 0.79 -0.0226 0.214 0.79 1.1225 1.0 SpOx1.1_006764 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D11 compound treatment 0.0032 0.241 0.89 0.0054 0.242 0.9 1.2639 1.0 SpOx1.1_006765 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D12 compound treatment -0.0068 0.231 0.85 -0.0076 0.229 0.85 1.2037 1.0 SpOx1.1_006766 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D13 compound treatment -0.0228 0.215 0.79 -0.0096 0.227 0.84 1.1566 0.9996 SpOx1.1_006767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D14 compound treatment 0.0072 0.245 0.91 0.0094 0.246 0.91 1.2848 1.0 SpOx1.1_006768 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D15 compound treatment -0.0188 0.219 0.81 -0.0186 0.218 0.81 1.1434 1.0 SpOx1.1_006769 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D16 compound treatment 0.0012 0.239 0.88 4.0E-4 0.237 0.88 1.2455 1.0 SpOx1.1_006770 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D17 compound treatment 0.0012 0.239 0.88 0.0024 0.239 0.89 1.2508 1.0 SpOx1.1_006771 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D18 compound treatment -0.0038 0.234 0.86 -0.0026 0.234 0.87 1.2246 1.0 2141884 SpOx1.1_006772 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCCc4ccccn4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D19 compound treatment -8.0E-4 0.237 0.88 0.0024 0.239 0.89 1.2455 1.0 SpOx1.1_006773 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D20 compound treatment -0.0108 0.227 0.84 -0.0086 0.228 0.84 1.1906 1.0 SpOx1.1_006774 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D21 compound treatment 0.0102 0.248 0.92 0.0094 0.246 0.91 1.2926 1.0 SpOx1.1_006775 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D22 compound treatment -0.0048 0.233 0.86 4.0E-4 0.237 0.88 1.2299 1.0 SpOx1.1_006776 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D23 mock treatment 0.0032 0.241 0.89 0.0054 0.242 0.9 1.2638 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 D24 mock treatment -0.4698 -0.232 -0.86 -0.4665 -0.23 -0.85 -1.2093 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E01 compound treatment -0.0018 0.236 0.87 -0.0086 0.228 0.84 1.214 0.9999 SpOx1.1_006777 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E02 compound treatment -8.0E-4 0.237 0.88 0.0054 0.242 0.9 1.2534 0.9999 SpOx1.1_006778 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E03 compound treatment 0.0012 0.239 0.88 0.0044 0.241 0.89 1.256 1.0 SpOx1.1_006779 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E04 compound treatment -0.0058 0.232 0.86 -0.0036 0.233 0.86 1.2167 1.0 SpOx1.1_006780 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E05 compound treatment 0.0072 0.245 0.91 0.0114 0.248 0.92 1.2901 1.0 SpOx1.1_006781 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E06 compound treatment 0.0052 0.243 0.9 0.0094 0.246 0.91 1.2795 1.0 SpOx1.1_006782 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E07 compound treatment -0.0078 0.23 0.85 -0.0056 0.231 0.86 1.2063 1.0 2141884 SpOx1.1_006783 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCCc4ccccn4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E08 compound treatment 0.0092 0.247 0.91 0.0074 0.244 0.9 1.2848 1.0 SpOx1.1_006784 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E09 compound treatment 0.0052 0.243 0.9 0.0094 0.246 0.91 1.2795 1.0 SpOx1.1_006785 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E10 compound treatment 0.0112 0.249 0.92 0.0194 0.256 0.95 1.3214 0.9999 SpOx1.1_006786 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E11 compound treatment 0.0022 0.24 0.89 0.0034 0.24 0.89 1.256 1.0 SpOx1.1_006787 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E12 compound treatment -0.0048 0.233 0.86 -0.0036 0.233 0.86 1.2194 1.0 SpOx1.1_006788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E13 compound treatment -0.0058 0.232 0.86 4.0E-4 0.237 0.88 1.2272 0.9999 SpOx1.1_006789 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E14 compound treatment -0.0058 0.232 0.86 0.0044 0.241 0.89 1.2376 0.9998 SpOx1.1_006790 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E15 compound treatment -0.0018 0.236 0.87 0.0024 0.239 0.89 1.2429 1.0 SpOx1.1_006791 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E16 compound treatment 0.0012 0.239 0.88 0.0024 0.239 0.89 1.2507 1.0 SpOx1.1_006792 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E17 compound treatment 0.0092 0.247 0.91 0.0154 0.252 0.93 1.3058 0.9999 SpOx1.1_006793 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E18 compound treatment 0.0012 0.239 0.88 0.0034 0.24 0.89 1.2534 1.0 SpOx1.1_006794 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E19 compound treatment 0.0012 0.239 0.88 0.0044 0.241 0.89 1.256 1.0 SpOx1.1_006795 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E20 compound treatment 0.0102 0.248 0.92 0.0124 0.249 0.92 1.3005 1.0 SpOx1.1_006796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E21 compound treatment 0.0092 0.247 0.91 0.0104 0.247 0.92 1.2926 1.0 SpOx1.1_006797 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E22 compound treatment 0.0142 0.252 0.93 0.0164 0.253 0.94 1.3215 1.0 SpOx1.1_006798 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E23 mock treatment -0.0028 0.235 0.87 -0.0016 0.235 0.87 1.2298 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 E24 mock treatment -0.4698 -0.232 -0.86 -0.4655 -0.229 -0.85 -1.2067 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F01 compound treatment -0.0128 0.225 0.83 -0.0076 0.229 0.85 1.1881 0.9999 SpOx1.1_006799 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F02 compound treatment -0.0158 0.222 0.82 -0.0096 0.227 0.84 1.1749 0.9999 SpOx1.1_006800 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F03 compound treatment 0.0082 0.246 0.91 0.0124 0.249 0.92 1.2953 1.0 SpOx1.1_006801 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F04 compound treatment 0.0092 0.247 0.91 0.0104 0.247 0.92 1.2927 1.0 SpOx1.1_006802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F05 compound treatment -0.0148 0.223 0.82 -0.0156 0.221 0.82 1.1618 1.0 SpOx1.1_006803 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F06 compound treatment 0.0012 0.239 0.88 0.0014 0.238 0.88 1.2481 1.0 SpOx1.1_006804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F07 compound treatment -0.0148 0.223 0.82 -0.0116 0.225 0.83 1.1724 1.0 SpOx1.1_006805 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F08 compound treatment 0.0052 0.243 0.9 0.0074 0.244 0.9 1.2743 1.0 SpOx1.1_006806 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F09 compound treatment 0.0082 0.246 0.91 0.0084 0.245 0.91 1.2848 1.0 SpOx1.1_006807 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F10 compound treatment 2.0E-4 0.238 0.88 0.0034 0.24 0.89 1.2507 1.0 SpOx1.1_006808 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F11 compound treatment -0.0088 0.229 0.85 -0.0096 0.227 0.84 1.1932 1.0 SpOx1.1_006809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F12 compound treatment -0.0188 0.219 0.81 -0.0116 0.225 0.83 1.1618 0.9999 SpOx1.1_006810 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F13 compound treatment 0.0072 0.245 0.91 0.0104 0.247 0.92 1.2874 1.0 SpOx1.1_006811 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F14 compound treatment 0.0062 0.244 0.9 0.0124 0.249 0.92 1.2901 0.9999 SpOx1.1_006812 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F15 compound treatment 0.0062 0.244 0.9 0.0084 0.245 0.91 1.2796 1.0 SpOx1.1_006813 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F16 compound treatment 0.0142 0.252 0.93 0.0124 0.249 0.92 1.311 1.0 SpOx1.1_006814 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F17 compound treatment 0.0012 0.239 0.88 0.0064 0.243 0.9 1.2613 1.0 SpOx1.1_006815 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F18 compound treatment 0.0202 0.258 0.95 0.0384 0.275 1.02 1.3948 0.9995 SpOx1.1_006816 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F19 compound treatment -0.0028 0.235 0.87 -0.0026 0.234 0.87 1.2272 1.0 SpOx1.1_006817 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F20 compound treatment -0.0068 0.231 0.85 -0.0026 0.234 0.87 1.2168 1.0 SpOx1.1_006818 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F21 compound treatment -0.0118 0.226 0.84 -0.0096 0.227 0.84 1.1854 1.0 2141884 SpOx1.1_006819 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCCc4ccccn4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F22 compound treatment 0.0092 0.247 0.91 0.0104 0.247 0.92 1.2927 1.0 SpOx1.1_006820 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F23 mock treatment -0.0078 0.23 0.85 -0.0116 0.225 0.83 1.1905 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 F24 mock treatment -0.471 -0.233 -0.86 -0.465 -0.228 -0.85 -1.2085 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G01 compound treatment -0.0178 0.22 0.81 -0.0086 0.228 0.84 1.1723 0.9998 SpOx1.1_006821 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G02 compound treatment -0.0248 0.213 0.79 -0.0206 0.216 0.8 1.1226 1.0 SpOx1.1_006822 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G03 compound treatment -0.0038 0.234 0.86 -0.0016 0.235 0.87 1.2272 1.0 SpOx1.1_006823 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G04 compound treatment -0.0088 0.229 0.85 -0.0056 0.231 0.86 1.2037 1.0 SpOx1.1_006824 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G05 compound treatment -0.0268 0.211 0.78 -0.0156 0.221 0.82 1.1305 0.9997 SpOx1.1_006825 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G06 compound treatment -0.0068 0.231 0.85 -0.0056 0.231 0.86 1.2089 1.0 SpOx1.1_006826 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G07 compound treatment 0.0092 0.247 0.91 0.0064 0.243 0.9 1.2822 1.0 SpOx1.1_006827 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G08 compound treatment -0.0138 0.224 0.83 -0.0116 0.225 0.83 1.1749 1.0 SpOx1.1_006828 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G09 compound treatment 0.0022 0.24 0.89 0.0064 0.243 0.9 1.2639 1.0 SpOx1.1_006829 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G10 compound treatment 2.0E-4 0.238 0.88 0.0024 0.239 0.89 1.2481 1.0 SpOx1.1_006830 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G11 compound treatment -0.0108 0.227 0.84 -0.0106 0.226 0.84 1.1854 1.0 SpOx1.1_006831 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G12 compound treatment -8.0E-4 0.237 0.88 0.0014 0.238 0.88 1.2429 1.0 SpOx1.1_006832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G13 compound treatment -0.0058 0.232 0.86 -0.0046 0.232 0.86 1.2141 1.0 SpOx1.1_006833 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G14 compound treatment -0.0108 0.227 0.84 -0.0086 0.228 0.84 1.1906 1.0 SpOx1.1_006834 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G15 compound treatment -0.0118 0.226 0.84 4.0E-4 0.237 0.88 1.2115 0.9997 SpOx1.1_006835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G16 compound treatment -0.0238 0.214 0.79 -0.0206 0.216 0.8 1.1251 1.0 SpOx1.1_006836 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G17 compound treatment -0.0058 0.232 0.86 -0.0046 0.232 0.86 1.2141 1.0 SpOx1.1_006837 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G18 compound treatment -0.0068 0.231 0.85 -0.0106 0.226 0.84 1.1959 1.0 SpOx1.1_006838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G19 compound treatment -0.0128 0.225 0.83 -0.0146 0.222 0.82 1.1695 1.0 SpOx1.1_006839 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G20 compound treatment -0.0138 0.224 0.83 -0.0156 0.221 0.82 1.1644 1.0 SpOx1.1_006840 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G21 compound treatment -0.0108 0.227 0.84 -0.0096 0.227 0.84 1.188 1.0 SpOx1.1_006841 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G22 compound treatment 2.0E-4 0.238 0.88 -0.0036 0.233 0.86 1.2325 1.0 SpOx1.1_006842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G23 mock treatment -0.0068 0.231 0.85 -0.0056 0.231 0.86 1.2089 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 G24 mock treatment -0.4708 -0.233 -0.86 -0.4665 -0.23 -0.85 -1.2119 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H01 compound treatment -0.0308 0.207 0.76 -0.0186 0.218 0.81 1.1122 0.9996 SpOx1.1_006843 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H02 compound treatment 0.0022 0.24 0.89 0.0034 0.24 0.89 1.256 1.0 SpOx1.1_006844 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H03 compound treatment -0.0168 0.221 0.82 -0.0136 0.223 0.83 1.1619 1.0 SpOx1.1_006845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H04 compound treatment -0.0038 0.234 0.86 -0.0066 0.23 0.85 1.2142 1.0 SpOx1.1_006846 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H05 compound treatment -0.0148 0.223 0.82 -0.0126 0.224 0.83 1.1697 1.0 SpOx1.1_006847 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H06 compound treatment -0.0218 0.216 0.8 -0.0186 0.218 0.81 1.1357 1.0 SpOx1.1_006848 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H07 compound treatment 0.0012 0.239 0.88 0.0034 0.24 0.89 1.2534 1.0 SpOx1.1_006849 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H08 compound treatment -0.0128 0.225 0.83 -0.0136 0.223 0.83 1.1723 1.0 SpOx1.1_006850 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H09 compound treatment -0.0128 0.225 0.83 -0.0106 0.226 0.84 1.18 1.0 SpOx1.1_006851 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H10 compound treatment 0.0042 0.242 0.89 0.0054 0.242 0.9 1.2665 1.0 SpOx1.1_006852 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H11 compound treatment -0.0108 0.227 0.84 -0.0086 0.228 0.84 1.1906 1.0 SpOx1.1_006853 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H12 compound treatment -0.0078 0.23 0.85 -0.0076 0.229 0.85 1.2011 1.0 SpOx1.1_006854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H13 compound treatment -0.0148 0.223 0.82 -0.0096 0.227 0.84 1.1775 0.9999 SpOx1.1_006855 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H14 compound treatment 2.0E-4 0.238 0.88 4.0E-4 0.237 0.88 1.2429 1.0 SpOx1.1_006856 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H15 compound treatment -0.0038 0.234 0.86 -0.0016 0.235 0.87 1.2273 1.0 SpOx1.1_006857 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H16 compound treatment -0.0018 0.236 0.87 -0.0036 0.233 0.86 1.2272 1.0 SpOx1.1_006858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H17 compound treatment -0.0148 0.223 0.82 -0.0126 0.224 0.83 1.1697 1.0 SpOx1.1_006859 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H18 compound treatment -0.0118 0.226 0.84 -0.0156 0.221 0.82 1.1697 1.0 SpOx1.1_006860 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H19 compound treatment -0.0168 0.221 0.82 -0.0196 0.217 0.8 1.1462 1.0 SpOx1.1_006861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H20 compound treatment -0.0118 0.226 0.84 -0.0076 0.229 0.85 1.1906 1.0 SpOx1.1_006862 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H21 compound treatment -0.0118 0.226 0.84 -0.0156 0.221 0.82 1.1696 1.0 SpOx1.1_006863 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H22 compound treatment -0.0018 0.236 0.87 -6.0E-4 0.236 0.87 1.2351 1.0 SpOx1.1_006864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H23 mock treatment 0.0102 0.248 0.92 0.0114 0.248 0.92 1.2978 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 H24 mock treatment -0.4698 -0.232 -0.86 -0.4675 -0.231 -0.86 -1.2119 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I01 compound treatment -0.0128 0.225 0.83 -0.0066 0.23 0.85 1.1906 0.9999 SpOx1.1_006865 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I02 compound treatment 0.0042 0.242 0.89 0.0054 0.242 0.9 1.2665 1.0 SpOx1.1_006866 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I03 compound treatment -0.0018 0.236 0.87 0.0064 0.243 0.9 1.2533 0.9999 SpOx1.1_006867 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I04 compound treatment -0.0268 0.211 0.78 -0.0236 0.213 0.79 1.1094 1.0 SpOx1.1_006868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I05 compound treatment 0.0032 0.241 0.89 0.0114 0.248 0.92 1.2796 0.9999 SpOx1.1_006869 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I06 compound treatment -0.0088 0.229 0.85 -0.0076 0.229 0.85 1.1984 1.0 SpOx1.1_006870 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I07 compound treatment -8.0E-4 0.237 0.88 0.0054 0.242 0.9 1.2533 0.9999 SpOx1.1_006871 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I08 compound treatment -0.0268 0.211 0.78 -0.0256 0.211 0.78 1.1041 1.0 2141884 SpOx1.1_006872 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCCc4ccccn4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I09 compound treatment -0.0078 0.23 0.85 -0.0046 0.232 0.86 1.2089 1.0 SpOx1.1_006873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I10 compound treatment 0.0022 0.24 0.89 0.0044 0.241 0.89 1.2586 1.0 SpOx1.1_006874 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I11 compound treatment -0.0018 0.236 0.87 4.0E-4 0.237 0.88 1.2377 1.0 SpOx1.1_006875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I12 compound treatment -0.0068 0.231 0.85 -0.0056 0.231 0.86 1.2089 1.0 SpOx1.1_006876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I13 compound treatment -0.0028 0.235 0.87 4.0E-4 0.237 0.88 1.2351 1.0 SpOx1.1_006877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I14 compound treatment -0.0138 0.224 0.83 -0.0046 0.232 0.86 1.1932 0.9998 SpOx1.1_006878 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I15 compound treatment -0.0198 0.218 0.81 -0.0156 0.221 0.82 1.1487 1.0 SpOx1.1_006879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I16 compound treatment -0.0138 0.224 0.83 -0.0186 0.218 0.81 1.1564 0.9999 SpOx1.1_006880 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I17 compound treatment -0.0078 0.23 0.85 -0.0026 0.234 0.87 1.2142 1.0 SpOx1.1_006881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I18 compound treatment -0.0338 0.204 0.75 -0.0246 0.212 0.79 1.0885 0.9998 SpOx1.1_006882 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I19 compound treatment 0.0042 0.242 0.89 0.0054 0.242 0.9 1.2665 1.0 SpOx1.1_006883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I20 compound treatment -0.0118 0.226 0.84 -0.0086 0.228 0.84 1.188 1.0 SpOx1.1_006884 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I21 compound treatment -0.0068 0.231 0.85 -0.0046 0.232 0.86 1.2115 1.0 SpOx1.1_006885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I22 compound treatment -8.0E-4 0.237 0.88 0.0044 0.241 0.89 1.2508 1.0 SpOx1.1_006886 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I23 mock treatment 2.0E-4 0.238 0.88 0.0034 0.24 0.89 1.2508 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 I24 mock treatment -0.4708 -0.233 -0.86 -0.4665 -0.23 -0.85 -1.2119 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J01 compound treatment -0.0218 0.216 0.8 -0.0206 0.216 0.8 1.1305 1.0 SpOx1.1_006887 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J02 compound treatment -0.0168 0.221 0.82 -0.0156 0.221 0.82 1.1565 1.0 SpOx1.1_006888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J03 compound treatment -0.0338 0.204 0.75 -0.0276 0.209 0.77 1.0806 0.9999 SpOx1.1_006889 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J04 compound treatment 2.0E-4 0.238 0.88 0.0054 0.242 0.9 1.2559 1.0 SpOx1.1_006890 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J05 compound treatment -0.0068 0.231 0.85 -0.0066 0.23 0.85 1.2063 1.0 SpOx1.1_006891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J06 compound treatment 0.0012 0.239 0.88 0.0024 0.239 0.89 1.2508 1.0 SpOx1.1_006892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J07 compound treatment -0.0138 0.224 0.83 -0.0196 0.217 0.8 1.1538 0.9999 SpOx1.1_006893 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J08 compound treatment -0.0088 0.229 0.85 -0.0146 0.222 0.82 1.1801 0.9999 SpOx1.1_006894 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J09 compound treatment -0.0138 0.224 0.83 -0.0136 0.223 0.83 1.1695 1.0 SpOx1.1_006895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J10 compound treatment -0.0118 0.226 0.84 -0.0156 0.221 0.82 1.1697 1.0 SpOx1.1_006896 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J11 compound treatment 0.0022 0.24 0.89 -0.0026 0.234 0.87 1.2403 0.9999 SpOx1.1_006897 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J12 compound treatment -8.0E-4 0.237 0.88 -0.0046 0.232 0.86 1.2272 1.0 SpOx1.1_006898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J13 compound treatment -0.0208 0.217 0.8 -0.0206 0.216 0.8 1.1331 1.0 SpOx1.1_006899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J14 compound treatment -0.0068 0.231 0.85 -0.0076 0.229 0.85 1.2037 1.0 SpOx1.1_006900 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J15 compound treatment -0.0178 0.22 0.81 -0.0216 0.215 0.8 1.1381 0.9999 SpOx1.1_006901 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J16 compound treatment -0.0278 0.21 0.78 -0.0286 0.208 0.77 1.0936 1.0 SpOx1.1_006902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J17 compound treatment -0.0218 0.216 0.8 -0.0266 0.21 0.78 1.1146 0.9999 SpOx1.1_006903 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J18 compound treatment -0.0018 0.236 0.87 -0.0126 0.224 0.83 1.2037 0.9997 SpOx1.1_006904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J19 compound treatment -0.0048 0.233 0.86 -0.0166 0.22 0.82 1.1854 0.9996 SpOx1.1_006905 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J20 compound treatment -8.0E-4 0.237 0.88 -0.0046 0.232 0.86 1.2272 1.0 SpOx1.1_006906 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J21 compound treatment 0.0022 0.24 0.89 -0.0016 0.235 0.87 1.2429 1.0 SpOx1.1_006907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J22 compound treatment -0.0378 0.2 0.74 -0.0386 0.198 0.73 1.0414 1.0 SpOx1.1_006908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J23 mock treatment -0.0098 0.228 0.84 -0.0086 0.228 0.84 1.1931 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 J24 mock treatment -0.4708 -0.233 -0.86 -0.4665 -0.23 -0.85 -1.2119 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K01 compound treatment -0.0148 0.223 0.82 -0.0086 0.228 0.84 1.1802 0.9999 SpOx1.1_006909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K02 compound treatment -0.0208 0.217 0.8 -0.0186 0.218 0.81 1.1383 1.0 SpOx1.1_006910 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K03 compound treatment -0.0198 0.218 0.81 -0.0146 0.222 0.82 1.1512 0.9999 SpOx1.1_006911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K04 compound treatment -0.0198 0.218 0.81 -0.0096 0.227 0.84 1.1644 0.9998 SpOx1.1_006912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K05 compound treatment -0.0038 0.234 0.86 0.0024 0.239 0.89 1.2377 0.9999 SpOx1.1_006913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K06 compound treatment -0.0138 0.224 0.83 -0.0086 0.228 0.84 1.1827 0.9999 SpOx1.1_006914 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K07 compound treatment 0.0042 0.242 0.89 0.0044 0.241 0.89 1.2638 1.0 SpOx1.1_006915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K08 compound treatment -0.0028 0.235 0.87 -6.0E-4 0.236 0.87 1.2324 1.0 SpOx1.1_006916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K09 compound treatment -0.0098 0.228 0.84 -0.0086 0.228 0.84 1.1932 1.0 SpOx1.1_006917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K10 compound treatment -0.0148 0.223 0.82 -0.0116 0.225 0.83 1.1724 1.0 SpOx1.1_006918 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K11 compound treatment -0.0038 0.234 0.86 0.0084 0.245 0.91 1.2533 0.9997 SpOx1.1_006919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K12 compound treatment -8.0E-4 0.237 0.88 4.0E-4 0.237 0.88 1.2403 1.0 SpOx1.1_006920 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K13 compound treatment -0.0188 0.219 0.81 -0.0116 0.225 0.83 1.1618 0.9999 SpOx1.1_006921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K14 compound treatment -0.0068 0.231 0.85 -0.0076 0.229 0.85 1.2036 1.0 SpOx1.1_006922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K15 compound treatment -0.0028 0.235 0.87 -0.0016 0.235 0.87 1.2298 1.0 SpOx1.1_006923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K16 compound treatment 2.0E-4 0.238 0.88 -0.0056 0.231 0.86 1.2273 0.9999 SpOx1.1_006924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K17 compound treatment -0.0158 0.222 0.82 -0.0156 0.221 0.82 1.1591 1.0 SpOx1.1_006925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K18 compound treatment -0.0208 0.217 0.8 -0.0206 0.216 0.8 1.1329 1.0 SpOx1.1_006926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K19 compound treatment -0.0218 0.216 0.8 -0.0176 0.219 0.81 1.1381 1.0 SpOx1.1_006927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K20 compound treatment -0.0098 0.228 0.84 -0.0096 0.227 0.84 1.1907 1.0 SpOx1.1_006928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K21 compound treatment -0.0168 0.221 0.82 -0.0156 0.221 0.82 1.1566 1.0 SpOx1.1_006929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K22 compound treatment -0.0058 0.232 0.86 -0.0036 0.233 0.86 1.2168 1.0 SpOx1.1_006930 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K23 mock treatment -0.0038 0.234 0.86 -0.0046 0.232 0.86 1.2193 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 K24 mock treatment -0.4698 -0.232 -0.86 -0.4665 -0.23 -0.85 -1.2093 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L01 compound treatment -0.0308 0.207 0.76 -0.0216 0.215 0.8 1.1042 0.9998 SpOx1.1_006931 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L02 compound treatment 0.0012 0.239 0.88 0.0044 0.241 0.89 1.256 1.0 SpOx1.1_006932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L03 compound treatment 0.0022 0.24 0.89 0.0074 0.244 0.9 1.2665 1.0 SpOx1.1_006933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L04 compound treatment -0.0058 0.232 0.86 -0.0026 0.234 0.87 1.2194 1.0 SpOx1.1_006934 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L05 compound treatment 0.0062 0.244 0.9 0.0074 0.244 0.9 1.277 1.0 SpOx1.1_006935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L06 compound treatment -0.0058 0.232 0.86 -0.0066 0.23 0.85 1.209 1.0 SpOx1.1_006936 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L07 compound treatment -0.0218 0.216 0.8 -0.0226 0.214 0.79 1.1252 1.0 SpOx1.1_006937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L08 compound treatment -0.0168 0.221 0.82 -0.0166 0.22 0.82 1.154 1.0 SpOx1.1_006938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L09 compound treatment 0.0062 0.244 0.9 0.0044 0.241 0.89 1.2691 1.0 SpOx1.1_006939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L10 compound treatment 0.0062 0.244 0.9 0.0044 0.241 0.89 1.2691 1.0 SpOx1.1_006940 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L11 compound treatment 0.0042 0.242 0.89 0.0064 0.243 0.9 1.269 1.0 SpOx1.1_006941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L12 compound treatment 0.0072 0.245 0.91 0.0054 0.242 0.9 1.2743 1.0 SpOx1.1_006942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L13 compound treatment 0.0032 0.241 0.89 0.0044 0.241 0.89 1.2613 1.0 SpOx1.1_006943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L14 compound treatment 0.0112 0.249 0.92 0.0064 0.243 0.9 1.2874 0.9999 SpOx1.1_006944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L15 compound treatment -0.0048 0.233 0.86 -0.0086 0.228 0.84 1.2063 1.0 SpOx1.1_006945 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L16 compound treatment 0.0072 0.245 0.91 0.0014 0.238 0.88 1.2639 0.9999 SpOx1.1_006946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L17 compound treatment 0.0162 0.254 0.94 0.0134 0.25 0.93 1.3188 1.0 SpOx1.1_006947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L18 compound treatment -0.0078 0.23 0.85 -0.0066 0.23 0.85 1.2037 1.0 SpOx1.1_006948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L19 compound treatment -0.0018 0.236 0.87 4.0E-4 0.237 0.88 1.2377 1.0 SpOx1.1_006949 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L20 compound treatment 0.0042 0.242 0.89 0.0044 0.241 0.89 1.2639 1.0 SpOx1.1_006950 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L21 compound treatment 0.0042 0.242 0.89 0.0044 0.241 0.89 1.2639 1.0 SpOx1.1_006951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L22 compound treatment 0.0122 0.25 0.92 0.0084 0.245 0.91 1.2953 1.0 SpOx1.1_006952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L23 mock treatment 0.0172 0.255 0.94 0.0064 0.243 0.9 1.3031 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 L24 mock treatment -0.471 -0.233 -0.86 -0.476 -0.239 -0.89 -1.2373 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M01 compound treatment 0.0162 0.254 0.94 0.0194 0.256 0.95 1.3346 1.0 SpOx1.1_006953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M02 compound treatment -8.0E-4 0.237 0.88 0.0014 0.238 0.88 1.2429 1.0 SpOx1.1_006954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M03 compound treatment 0.0132 0.251 0.93 0.0184 0.255 0.94 1.3241 1.0 SpOx1.1_006955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M04 compound treatment 0.0092 0.247 0.91 0.0134 0.25 0.93 1.3004 1.0 SpOx1.1_006956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M05 compound treatment 0.0032 0.241 0.89 0.0064 0.243 0.9 1.2665 1.0 SpOx1.1_006957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M06 compound treatment -0.0098 0.228 0.84 -0.0036 0.233 0.86 1.2063 0.9999 SpOx1.1_006958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M07 compound treatment 0.0092 0.247 0.91 0.0134 0.25 0.93 1.3005 1.0 SpOx1.1_006959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M08 compound treatment 0.0082 0.246 0.91 0.0054 0.242 0.9 1.277 1.0 SpOx1.1_006960 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M09 compound treatment 0.0132 0.251 0.93 0.0104 0.247 0.92 1.3031 1.0 SpOx1.1_006961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M10 compound treatment -0.0118 0.226 0.84 -0.0076 0.229 0.85 1.1907 1.0 SpOx1.1_006962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M11 compound treatment -8.0E-4 0.237 0.88 4.0E-4 0.237 0.88 1.2403 1.0 SpOx1.1_006963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M12 compound treatment -0.0098 0.228 0.84 -0.0106 0.226 0.84 1.1881 1.0 SpOx1.1_006964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M13 compound treatment -0.0038 0.234 0.86 -0.0036 0.233 0.86 1.2221 1.0 SpOx1.1_006965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M14 compound treatment 0.0082 0.246 0.91 0.0074 0.244 0.9 1.2822 1.0 SpOx1.1_006966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M15 compound treatment -0.0018 0.236 0.87 -0.0066 0.23 0.85 1.2194 0.9999 SpOx1.1_006967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M16 compound treatment -0.0198 0.218 0.81 -0.0206 0.216 0.8 1.1355 1.0 SpOx1.1_006968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M17 compound treatment 0.0212 0.259 0.96 0.0164 0.253 0.94 1.3398 0.9999 SpOx1.1_006969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M18 compound treatment 0.0122 0.25 0.92 0.0114 0.248 0.92 1.3031 1.0 SpOx1.1_006970 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M19 compound treatment -0.0038 0.234 0.86 -0.0106 0.226 0.84 1.2037 0.9999 SpOx1.1_006971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M20 compound treatment -0.0048 0.233 0.86 -6.0E-4 0.236 0.87 1.2272 1.0 SpOx1.1_006972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M21 compound treatment 0.0152 0.253 0.94 0.0114 0.248 0.92 1.311 1.0 SpOx1.1_006973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M22 compound treatment 0.0012 0.239 0.88 0.0064 0.243 0.9 1.2613 1.0 SpOx1.1_006974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M23 mock treatment 0.0072 0.245 0.91 0.0064 0.243 0.9 1.2769 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 M24 mock treatment -0.4688 -0.231 -0.85 -0.4685 -0.232 -0.86 -1.2119 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N01 compound treatment -0.0098 0.228 0.84 -0.0046 0.232 0.86 1.2037 1.0 SpOx1.1_006975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N02 compound treatment -0.0228 0.215 0.79 -0.0176 0.219 0.81 1.1357 0.9999 SpOx1.1_006976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N03 compound treatment -0.0088 0.229 0.85 -0.0026 0.234 0.87 1.2115 0.9999 SpOx1.1_006977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N04 compound treatment -0.0138 0.224 0.83 -0.0096 0.227 0.84 1.18 1.0 SpOx1.1_006978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N05 compound treatment -8.0E-4 0.237 0.88 0.0054 0.242 0.9 1.2534 0.9999 SpOx1.1_006979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N06 compound treatment -0.0198 0.218 0.81 -0.0196 0.217 0.8 1.1382 1.0 SpOx1.1_006980 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N07 compound treatment -0.0128 0.225 0.83 -0.0096 0.227 0.84 1.1828 1.0 SpOx1.1_006981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N08 compound treatment -0.0098 0.228 0.84 -0.0066 0.23 0.85 1.1984 1.0 SpOx1.1_006982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N09 compound treatment -0.0268 0.211 0.78 -0.0266 0.21 0.78 1.1015 1.0 SpOx1.1_006983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N10 compound treatment 0.0022 0.24 0.89 0.0014 0.238 0.88 1.2508 1.0 SpOx1.1_006984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N11 compound treatment -0.0178 0.22 0.81 -0.0216 0.215 0.8 1.1383 0.9999 SpOx1.1_006985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N12 compound treatment -0.0058 0.232 0.86 -0.0046 0.232 0.86 1.2141 1.0 SpOx1.1_006986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N13 compound treatment 2.0E-4 0.238 0.88 -0.0016 0.235 0.87 1.2377 1.0 SpOx1.1_006987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N14 compound treatment -0.0098 0.228 0.84 -0.0106 0.226 0.84 1.188 1.0 SpOx1.1_006988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N15 compound treatment 0.0072 0.245 0.91 0.0034 0.24 0.89 1.2691 1.0 SpOx1.1_006989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N16 compound treatment 0.0032 0.241 0.89 0.0014 0.238 0.88 1.2534 1.0 SpOx1.1_006990 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N17 compound treatment -0.0108 0.227 0.84 -0.0126 0.224 0.83 1.1802 1.0 SpOx1.1_006991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N18 compound treatment 0.0072 0.245 0.91 0.0024 0.239 0.89 1.2665 0.9999 SpOx1.1_006992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N19 compound treatment -0.0028 0.235 0.87 -0.0036 0.233 0.86 1.2246 1.0 SpOx1.1_006993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N20 compound treatment 0.0022 0.24 0.89 -6.0E-4 0.236 0.87 1.2455 1.0 SpOx1.1_006994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N21 compound treatment -0.0068 0.231 0.85 -0.0076 0.229 0.85 1.2037 1.0 SpOx1.1_006995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N22 compound treatment 0.0022 0.24 0.89 0.0014 0.238 0.88 1.2508 1.0 SpOx1.1_006996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N23 mock treatment 0.0042 0.242 0.89 0.0064 0.243 0.9 1.2691 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 N24 mock treatment -0.4698 -0.232 -0.86 -0.4685 -0.232 -0.86 -1.2145 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O01 compound treatment -0.0138 0.224 0.83 0.0054 0.242 0.9 1.2194 0.9992 SpOx1.1_006997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O02 compound treatment -0.0068 0.231 0.85 0.0034 0.24 0.89 1.2325 0.9998 SpOx1.1_006998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O03 compound treatment -0.0028 0.235 0.87 0.0054 0.242 0.9 1.2482 0.9999 SpOx1.1_006999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O04 compound treatment 2.0E-4 0.238 0.88 0.0024 0.239 0.89 1.2482 1.0 SpOx1.1_007000 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O05 compound treatment -0.0028 0.235 0.87 0.0034 0.24 0.89 1.243 0.9999 SpOx1.1_007001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O06 compound treatment -0.0088 0.229 0.85 -0.0046 0.232 0.86 1.2063 1.0 SpOx1.1_007002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O07 compound treatment 2.0E-4 0.238 0.88 0.0044 0.241 0.89 1.2534 1.0 SpOx1.1_007003 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O08 compound treatment 0.0152 0.253 0.94 0.0104 0.247 0.92 1.3084 0.9999 SpOx1.1_007004 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O09 compound treatment -0.0088 0.229 0.85 -0.0076 0.229 0.85 1.1985 1.0 SpOx1.1_007005 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O10 compound treatment -0.0108 0.227 0.84 -0.0066 0.23 0.85 1.1958 1.0 SpOx1.1_007006 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O11 compound treatment 2.0E-4 0.238 0.88 -6.0E-4 0.236 0.87 1.2403 1.0 SpOx1.1_007007 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O12 compound treatment -0.0168 0.221 0.82 -0.0066 0.23 0.85 1.1801 0.9998 SpOx1.1_007008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O13 compound treatment 2.0E-4 0.238 0.88 0.0034 0.24 0.89 1.2508 1.0 SpOx1.1_007009 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O14 compound treatment 0.0052 0.243 0.9 0.0034 0.24 0.89 1.2639 1.0 SpOx1.1_007010 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O15 compound treatment 0.0122 0.25 0.92 0.0064 0.243 0.9 1.29 0.9999 SpOx1.1_007011 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O16 compound treatment 0.0152 0.253 0.94 0.0134 0.25 0.93 1.3162 1.0 SpOx1.1_007012 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O17 compound treatment 0.0062 0.244 0.9 0.0074 0.244 0.9 1.277 1.0 SpOx1.1_007013 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O18 compound treatment -0.0098 0.228 0.84 -0.0106 0.226 0.84 1.188 1.0 SpOx1.1_007014 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O19 compound treatment 0.0122 0.25 0.92 0.0094 0.246 0.91 1.2979 1.0 SpOx1.1_007015 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O20 compound treatment -0.0088 0.229 0.85 -0.0066 0.23 0.85 1.2011 1.0 SpOx1.1_007016 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O21 compound treatment 0.0032 0.241 0.89 0.0024 0.239 0.89 1.256 1.0 SpOx1.1_007017 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O22 compound treatment 0.0052 0.243 0.9 0.0074 0.244 0.9 1.2743 1.0 SpOx1.1_007018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O23 mock treatment 0.0022 0.24 0.89 0.0034 0.24 0.89 1.2559 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 O24 mock treatment -0.4698 -0.232 -0.86 -0.4685 -0.232 -0.86 -1.2145 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P01 compound treatment -0.0198 0.218 0.81 -0.0146 0.222 0.82 1.1513 0.9999 SpOx1.1_007019 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P02 compound treatment -0.0148 0.223 0.82 -0.0126 0.224 0.83 1.1696 1.0 SpOx1.1_007020 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P03 compound treatment -0.0128 0.225 0.83 -0.0186 0.218 0.81 1.1592 0.9999 SpOx1.1_007021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P04 compound treatment -0.0138 0.224 0.83 -0.0166 0.22 0.82 1.1617 1.0 SpOx1.1_007022 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P05 compound treatment -0.0418 0.196 0.72 -0.0396 0.197 0.73 1.0283 1.0 SpOx1.1_007023 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P06 compound treatment -0.0248 0.213 0.79 -0.0266 0.21 0.78 1.1067 1.0 SpOx1.1_007024 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P07 compound treatment -0.0228 0.215 0.79 -0.0186 0.218 0.81 1.1331 1.0 SpOx1.1_007025 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P08 compound treatment -0.0208 0.217 0.8 -0.0206 0.216 0.8 1.1331 1.0 SpOx1.1_007026 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P09 compound treatment -0.0238 0.214 0.79 -0.0166 0.22 0.82 1.1357 0.9999 SpOx1.1_007027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P10 compound treatment -0.0338 0.204 0.75 -0.0336 0.203 0.75 1.065 1.0 SpOx1.1_007028 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P11 compound treatment -0.0338 0.204 0.75 -0.0376 0.199 0.74 1.0545 0.9999 SpOx1.1_007029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P12 compound treatment -0.0198 0.218 0.81 -0.0156 0.221 0.82 1.1488 1.0 SpOx1.1_007030 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P13 compound treatment -0.0258 0.212 0.78 -0.0276 0.209 0.77 1.1015 1.0 SpOx1.1_007031 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P14 compound treatment -0.0118 0.226 0.84 -0.0186 0.218 0.81 1.1619 0.9999 SpOx1.1_007032 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P15 compound treatment -0.0048 0.233 0.86 -0.0126 0.224 0.83 1.1959 0.9998 SpOx1.1_007033 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P16 compound treatment -0.0208 0.217 0.8 -0.0236 0.213 0.79 1.1252 1.0 SpOx1.1_007034 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P17 compound treatment -0.0258 0.212 0.78 -0.0306 0.206 0.76 1.0937 0.9999 SpOx1.1_007035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P18 compound treatment -0.0108 0.227 0.84 -0.0126 0.224 0.83 1.1801 1.0 SpOx1.1_007036 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P19 compound treatment -0.0108 0.227 0.84 -0.0096 0.227 0.84 1.188 1.0 SpOx1.1_007037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P20 compound treatment -0.0148 0.223 0.82 -0.0206 0.216 0.8 1.1487 0.9999 SpOx1.1_007038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P21 compound treatment 0.0142 0.252 0.93 0.0074 0.244 0.9 1.2979 0.9999 SpOx1.1_007039 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P22 compound treatment -0.0108 0.227 0.84 -0.0166 0.22 0.82 1.1696 0.9999 SpOx1.1_007040 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P23 mock treatment 0.0022 0.24 0.89 -0.0046 0.232 0.86 1.2351 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1298 P24 mock treatment -0.4678 -0.23 -0.85 -0.4725 -0.236 -0.87 -1.2198 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A01 compound treatment -0.0787 0.159 0.59 -0.0436 0.192 0.71 0.9204 0.9955 SpOx1.1_007041 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A02 compound treatment -0.0593 0.179 0.66 -0.0476 0.188 0.7 0.9606 0.9996 SpOx1.1_007042 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A03 compound treatment -0.0423 0.196 0.72 -0.0696 0.166 0.62 0.9474 0.9968 SpOx1.1_007043 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A04 compound treatment -0.0203 0.218 0.81 -0.0446 0.191 0.71 1.0704 0.998 SpOx1.1_007044 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A05 compound treatment -0.0523 0.186 0.69 -0.0506 0.185 0.69 0.9711 1.0 SpOx1.1_007045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A06 compound treatment -0.0593 0.179 0.66 -0.0706 0.165 0.61 0.9003 0.9993 SpOx1.1_007046 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A07 compound treatment -0.0313 0.207 0.76 -0.0636 0.172 0.64 0.9919 0.996 SpOx1.1_007047 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A08 compound treatment -0.0253 0.213 0.79 -0.0066 0.229 0.85 1.1569 0.9993 SpOx1.1_007048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A09 compound treatment -0.0727 0.165 0.61 -0.0486 0.187 0.69 0.923 0.998 SpOx1.1_007049 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A10 compound treatment -0.0673 0.171 0.63 -0.0486 0.187 0.69 0.9371 0.9989 SpOx1.1_007050 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A11 compound treatment -0.0553 0.183 0.68 -0.0516 0.184 0.68 0.9606 1.0 SpOx1.1_007051 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A12 compound treatment -0.0573 0.181 0.67 -0.0466 0.189 0.7 0.9685 0.9997 SpOx1.1_007052 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A13 compound treatment -0.0463 0.192 0.71 -0.0506 0.185 0.69 0.9867 0.9999 SpOx1.1_007053 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A14 compound treatment -0.0857 0.152 0.56 -0.0696 0.166 0.62 0.8339 0.999 SpOx1.1_007054 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A15 compound treatment -0.0523 0.186 0.69 -0.0546 0.181 0.67 0.9606 0.9999 SpOx1.1_007055 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A16 compound treatment -0.0723 0.166 0.61 -0.0506 0.185 0.69 0.9188 0.9984 SpOx1.1_007056 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A17 compound treatment -0.0573 0.181 0.67 -0.0376 0.198 0.73 0.992 0.9989 SpOx1.1_007057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A18 compound treatment -0.0563 0.182 0.67 -0.0586 0.177 0.66 0.9396 0.9999 SpOx1.1_007058 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A19 compound treatment -0.0343 0.204 0.75 -0.0196 0.216 0.8 1.0993 0.9995 SpOx1.1_007059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A20 compound treatment -0.0613 0.177 0.65 -0.0706 0.165 0.61 0.8951 0.9995 SpOx1.1_007060 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A21 compound treatment -0.0807 0.157 0.58 -0.0566 0.179 0.66 0.8811 0.9978 SpOx1.1_007061 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A22 compound treatment -0.0747 0.163 0.6 -0.0706 0.165 0.61 0.8601 1.0 SpOx1.1_007062 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A23 mock treatment -0.0733 0.165 0.61 -0.0676 0.168 0.62 0.8716 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 A24 mock treatment -0.4676 -0.23 -0.85 -0.466 -0.23 -0.85 -1.2032 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B01 compound treatment 0.0107 0.249 0.92 0.0164 0.252 0.93 1.3113 1.0 SpOx1.1_007063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B02 compound treatment 0.0097 0.248 0.92 0.0094 0.245 0.91 1.2904 1.0 2141853 SpOx1.1_007064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCc4nc5ccccc5[nH]4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B03 compound treatment 0.0257 0.264 0.98 0.0204 0.256 0.95 1.361 0.9999 SpOx1.1_007065 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B04 compound treatment 0.0287 0.267 0.99 0.0204 0.256 0.95 1.3689 0.9998 SpOx1.1_007066 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B05 compound treatment 0.0227 0.261 0.96 0.0204 0.256 0.95 1.3532 1.0 SpOx1.1_007067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B06 compound treatment 0.0077 0.246 0.91 0.0214 0.257 0.95 1.3166 0.9997 SpOx1.1_007068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B07 compound treatment 0.0217 0.26 0.96 0.0154 0.251 0.93 1.3375 0.9999 SpOx1.1_007069 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B08 compound treatment 0.0407 0.279 1.03 0.0484 0.284 1.05 1.4736 0.9999 SpOx1.1_007070 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B09 compound treatment 0.0197 0.258 0.95 0.0354 0.271 1.01 1.3847 0.9996 SpOx1.1_007071 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B10 compound treatment 0.0147 0.253 0.93 0.0294 0.265 0.98 1.3559 0.9997 SpOx1.1_007072 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B11 compound treatment 0.0247 0.263 0.97 0.0354 0.271 1.01 1.3977 0.9999 SpOx1.1_007073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B12 compound treatment 0.0147 0.253 0.93 0.0234 0.259 0.96 1.3401 0.9999 SpOx1.1_007074 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B13 compound treatment 0.0087 0.247 0.91 0.0664 0.302 1.12 1.4371 0.9948 SpOx1.1_007075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B14 compound treatment 0.0297 0.268 0.99 0.0254 0.261 0.97 1.3846 0.9999 SpOx1.1_007076 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B15 compound treatment 0.0027 0.241 0.89 -0.0026 0.233 0.86 1.2406 0.9999 SpOx1.1_007077 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B16 compound treatment 0.0177 0.256 0.95 0.0214 0.257 0.95 1.3428 1.0 SpOx1.1_007078 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B17 compound treatment 0.0237 0.262 0.97 0.0144 0.25 0.93 1.3401 0.9998 SpOx1.1_007079 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B18 compound treatment 0.0107 0.249 0.92 0.0184 0.254 0.94 1.3166 0.9999 SpOx1.1_007080 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B19 compound treatment 0.0157 0.254 0.94 0.0284 0.264 0.98 1.3559 0.9998 SpOx1.1_007081 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B20 compound treatment 0.0187 0.257 0.95 0.0224 0.258 0.96 1.348 1.0 SpOx1.1_007082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B21 compound treatment 0.0137 0.252 0.93 0.0604 0.296 1.1 1.4345 0.9966 SpOx1.1_007083 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B22 compound treatment 0.0027 0.241 0.89 0.0174 0.253 0.94 1.2931 0.9997 SpOx1.1_007084 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B23 mock treatment 0.0067 0.245 0.9 -0.0046 0.231 0.86 1.2459 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 B24 mock treatment -0.4706 -0.233 -0.86 -0.467 -0.231 -0.86 -1.2137 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C01 compound treatment 0.0167 0.255 0.94 0.0204 0.256 0.95 1.3375 1.0 SpOx1.1_007085 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C02 compound treatment 0.0157 0.254 0.94 0.0034 0.239 0.89 1.2904 0.9996 SpOx1.1_007086 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C03 compound treatment 0.0067 0.245 0.9 0.0044 0.24 0.89 1.2694 1.0 SpOx1.1_007087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C04 compound treatment 0.0167 0.255 0.94 -0.0066 0.229 0.85 1.2668 0.9987 SpOx1.1_007088 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C05 compound treatment 0.0287 0.267 0.99 -0.0046 0.231 0.86 1.3034 0.9975 SpOx1.1_007089 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C06 compound treatment -0.0023 0.236 0.87 0.0084 0.244 0.91 1.2564 0.9998 SpOx1.1_007090 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C07 compound treatment 0.0137 0.252 0.93 0.0174 0.253 0.94 1.3218 1.0 SpOx1.1_007091 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C08 compound treatment 0.0207 0.259 0.96 0.0294 0.265 0.98 1.3716 0.9999 SpOx1.1_007092 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C09 compound treatment 0.0337 0.272 1.0 0.0434 0.279 1.03 1.4422 0.9999 SpOx1.1_007093 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C10 compound treatment -0.0043 0.234 0.86 0.0174 0.253 0.94 1.2748 0.9992 SpOx1.1_007094 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C11 compound treatment 0.0197 0.258 0.95 0.0304 0.266 0.99 1.3716 0.9999 SpOx1.1_007095 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C12 compound treatment 0.0227 0.261 0.96 0.0264 0.262 0.97 1.3689 1.0 SpOx1.1_007096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C13 compound treatment 0.0037 0.242 0.89 0.0154 0.251 0.93 1.2904 0.9998 SpOx1.1_007097 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C14 compound treatment -0.0013 0.237 0.88 0.0144 0.25 0.93 1.2747 0.9996 SpOx1.1_007098 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C15 compound treatment 0.0057 0.244 0.9 0.0164 0.252 0.93 1.2983 0.9998 SpOx1.1_007099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C16 compound treatment 0.0087 0.247 0.91 0.0174 0.253 0.94 1.3087 0.9999 SpOx1.1_007100 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C17 compound treatment -0.0063 0.232 0.86 -0.0026 0.233 0.86 1.2171 1.0 SpOx1.1_007101 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C18 compound treatment 0.0157 0.254 0.94 0.0294 0.265 0.98 1.3585 0.9997 SpOx1.1_007102 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C19 compound treatment -0.0033 0.235 0.87 0.0284 0.264 0.98 1.3062 0.9982 SpOx1.1_007103 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C20 compound treatment 0.0037 0.242 0.89 0.0104 0.246 0.91 1.2773 0.9999 SpOx1.1_007104 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C21 compound treatment -3.0E-4 0.238 0.88 0.0194 0.255 0.95 1.2904 0.9993 SpOx1.1_007105 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C22 compound treatment 0.0017 0.24 0.89 0.0114 0.247 0.92 1.2747 0.9999 SpOx1.1_007106 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C23 mock treatment -0.0183 0.22 0.81 -0.0216 0.214 0.79 1.136 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 C24 mock treatment -0.4696 -0.232 -0.86 -0.468 -0.232 -0.86 -1.2137 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D01 compound treatment 7.0E-4 0.239 0.88 0.0034 0.239 0.89 1.2511 1.0 SpOx1.1_007107 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D02 compound treatment -0.0103 0.228 0.84 0.0074 0.243 0.9 1.2329 0.9994 SpOx1.1_007108 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D03 compound treatment 0.0017 0.24 0.89 0.0134 0.249 0.92 1.28 0.9998 SpOx1.1_007109 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D04 compound treatment -0.0163 0.222 0.82 0.0204 0.256 0.95 1.2512 0.9973 SpOx1.1_007110 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D05 compound treatment -3.0E-4 0.238 0.88 0.0074 0.243 0.9 1.259 0.9999 SpOx1.1_007111 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D06 compound treatment -0.0053 0.233 0.86 0.0014 0.237 0.88 1.2302 0.9999 SpOx1.1_007112 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D07 compound treatment 0.0077 0.246 0.91 0.0094 0.245 0.91 1.2852 1.0 SpOx1.1_007113 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D08 compound treatment 0.0027 0.241 0.89 0.0234 0.259 0.96 1.3088 0.9993 SpOx1.1_007114 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D09 compound treatment 0.0067 0.245 0.9 0.0024 0.238 0.88 1.2642 0.9999 SpOx1.1_007115 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D10 compound treatment -0.0093 0.229 0.85 0.0054 0.241 0.89 1.2302 0.9996 SpOx1.1_007116 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D11 compound treatment 0.0157 0.254 0.94 0.0234 0.259 0.96 1.3427 0.9999 SpOx1.1_007117 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D12 compound treatment -0.0013 0.237 0.88 0.0204 0.256 0.95 1.2905 0.9992 SpOx1.1_007118 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D13 compound treatment 0.0137 0.252 0.93 0.0184 0.254 0.94 1.3244 1.0 SpOx1.1_007119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D14 compound treatment -0.0033 0.235 0.87 0.0314 0.267 0.99 1.314 0.9978 SpOx1.1_007120 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D15 compound treatment -0.0063 0.232 0.86 0.0044 0.24 0.89 1.2354 0.9998 SpOx1.1_007121 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D16 compound treatment 0.0097 0.248 0.92 0.0284 0.264 0.98 1.3402 0.9994 SpOx1.1_007122 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D17 compound treatment 0.0227 0.261 0.96 0.0794 0.315 1.17 1.5078 0.9955 SpOx1.1_007123 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D18 compound treatment 0.0017 0.24 0.89 0.0184 0.254 0.94 1.2931 0.9995 SpOx1.1_007124 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D19 compound treatment -0.0023 0.236 0.87 0.0104 0.246 0.91 1.2616 0.9997 SpOx1.1_007125 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D20 compound treatment 0.0067 0.245 0.9 0.0054 0.241 0.89 1.2721 1.0 SpOx1.1_007126 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D21 compound treatment -0.0213 0.217 0.8 0.0024 0.238 0.88 1.191 0.9988 SpOx1.1_007127 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D22 compound treatment 0.0177 0.256 0.95 0.0194 0.255 0.95 1.3375 1.0 SpOx1.1_007128 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D23 mock treatment -0.0083 0.23 0.85 0.0034 0.239 0.89 1.2276 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 D24 mock treatment -0.4676 -0.23 -0.85 -0.467 -0.231 -0.86 -1.2058 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E01 compound treatment 0.0177 0.256 0.95 0.0214 0.257 0.95 1.3427 1.0 SpOx1.1_007129 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E02 compound treatment 0.0197 0.258 0.95 0.0204 0.256 0.95 1.3454 1.0 SpOx1.1_007130 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E03 compound treatment 0.0297 0.268 0.99 0.0204 0.256 0.95 1.3715 0.9998 SpOx1.1_007131 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E04 compound treatment 0.0227 0.261 0.96 0.0134 0.249 0.92 1.3349 0.9998 SpOx1.1_007132 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E05 compound treatment 0.0237 0.262 0.97 0.0214 0.257 0.95 1.3584 1.0 SpOx1.1_007133 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E06 compound treatment 0.0217 0.26 0.96 0.0304 0.266 0.99 1.3768 0.9999 SpOx1.1_007134 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E07 compound treatment 0.0277 0.266 0.98 0.0224 0.258 0.96 1.3715 0.9999 SpOx1.1_007135 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E08 compound treatment 0.0317 0.27 1.0 0.0314 0.267 0.99 1.4056 1.0 SpOx1.1_007136 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E09 compound treatment 0.0287 0.267 0.99 0.0204 0.256 0.95 1.3689 0.9998 SpOx1.1_007137 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E10 compound treatment 0.0257 0.264 0.98 0.0414 0.277 1.03 1.4161 0.9997 SpOx1.1_007138 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E11 compound treatment -0.0033 0.235 0.87 0.0244 0.26 0.96 1.2957 0.9986 SpOx1.1_007139 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E12 compound treatment 0.0267 0.265 0.98 0.0154 0.251 0.93 1.3506 0.9997 SpOx1.1_007140 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E13 compound treatment 0.0107 0.249 0.92 0.0184 0.254 0.94 1.3166 0.9999 SpOx1.1_007141 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E14 compound treatment -0.0033 0.235 0.87 0.0184 0.254 0.94 1.28 0.9992 SpOx1.1_007142 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E15 compound treatment 0.0397 0.278 1.03 0.0244 0.26 0.96 1.4081 0.9995 SpOx1.1_007143 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E16 compound treatment 0.0137 0.252 0.93 0.0214 0.257 0.95 1.3323 0.9999 SpOx1.1_007144 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E17 compound treatment 0.0037 0.242 0.89 0.0254 0.261 0.97 1.3166 0.9992 SpOx1.1_007145 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E18 compound treatment 0.0177 0.256 0.95 0.0204 0.256 0.95 1.3401 1.0 SpOx1.1_007146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E19 compound treatment 0.0137 0.252 0.93 0.0224 0.258 0.96 1.3349 0.9999 SpOx1.1_007147 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E20 compound treatment 0.0097 0.248 0.92 0.0214 0.257 0.95 1.3218 0.9998 SpOx1.1_007148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E21 compound treatment -0.0043 0.234 0.86 0.0134 0.249 0.92 1.2642 0.9994 SpOx1.1_007149 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E22 compound treatment 0.0267 0.265 0.98 0.0274 0.263 0.98 1.382 1.0 SpOx1.1_007150 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E23 mock treatment 0.0017 0.24 0.89 -0.0026 0.233 0.86 1.238 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 E24 mock treatment -0.4676 -0.23 -0.85 -0.467 -0.231 -0.86 -1.2058 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F01 compound treatment 0.0097 0.248 0.92 0.0104 0.246 0.91 1.293 1.0 SpOx1.1_007151 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F02 compound treatment 0.0077 0.246 0.91 0.0124 0.248 0.92 1.293 1.0 SpOx1.1_007152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F03 compound treatment 0.0167 0.255 0.94 0.0224 0.258 0.96 1.3428 1.0 SpOx1.1_007153 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F04 compound treatment -0.0113 0.227 0.84 0.0214 0.257 0.95 1.2669 0.998 SpOx1.1_007154 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F05 compound treatment 0.0267 0.265 0.98 0.0114 0.247 0.92 1.3401 0.9995 SpOx1.1_007155 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F06 compound treatment 0.0097 0.248 0.92 0.0204 0.256 0.95 1.3192 0.9998 SpOx1.1_007156 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F07 compound treatment 0.0087 0.247 0.91 0.0104 0.246 0.91 1.2904 1.0 SpOx1.1_007157 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F08 compound treatment 0.0097 0.248 0.92 0.0324 0.268 0.99 1.3507 0.9992 SpOx1.1_007158 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F09 compound treatment -0.0133 0.225 0.83 0.0244 0.26 0.96 1.2695 0.9973 SpOx1.1_007159 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F10 compound treatment 0.0287 0.267 0.99 0.0234 0.259 0.96 1.3768 0.9999 SpOx1.1_007160 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F11 compound treatment 0.0027 0.241 0.89 0.0174 0.253 0.94 1.293 0.9997 SpOx1.1_007161 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F12 compound treatment 0.0097 0.248 0.92 0.0084 0.244 0.91 1.2878 1.0 SpOx1.1_007162 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F13 compound treatment 0.0267 0.265 0.98 0.0274 0.263 0.98 1.382 1.0 SpOx1.1_007163 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F14 compound treatment 0.0157 0.254 0.94 0.0454 0.281 1.04 1.4004 0.9986 SpOx1.1_007164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F15 compound treatment 0.0127 0.251 0.93 0.0344 0.27 1.0 1.3637 0.9993 SpOx1.1_007165 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F16 compound treatment 0.0207 0.259 0.96 0.0294 0.265 0.98 1.3716 0.9999 SpOx1.1_007166 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F17 compound treatment 0.0087 0.247 0.91 0.0184 0.254 0.94 1.3114 0.9999 SpOx1.1_007167 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F18 compound treatment 0.0077 0.246 0.91 0.0324 0.268 0.99 1.3454 0.999 SpOx1.1_007168 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F19 compound treatment 0.0157 0.254 0.94 0.0214 0.257 0.95 1.3375 1.0 SpOx1.1_007169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F20 compound treatment 0.0157 0.254 0.94 0.0154 0.251 0.93 1.3218 1.0 SpOx1.1_007170 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F21 compound treatment 0.0147 0.253 0.93 0.0274 0.263 0.98 1.3506 0.9998 SpOx1.1_007171 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F22 compound treatment 0.0247 0.263 0.97 0.0324 0.268 0.99 1.3899 0.9999 SpOx1.1_007172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F23 mock treatment 0.0137 0.252 0.93 -0.0096 0.226 0.84 1.2511 0.9986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 F24 mock treatment -0.4686 -0.231 -0.85 -0.467 -0.231 -0.86 -1.2084 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G01 compound treatment 0.0197 0.258 0.95 0.0044 0.24 0.89 1.3034 0.9994 SpOx1.1_007173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G02 compound treatment 7.0E-4 0.239 0.88 0.0124 0.248 0.92 1.2747 0.9998 SpOx1.1_007174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G03 compound treatment 0.0157 0.254 0.94 0.0224 0.258 0.96 1.3401 1.0 SpOx1.1_007175 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G04 compound treatment 0.0207 0.259 0.96 0.0084 0.244 0.91 1.3165 0.9996 SpOx1.1_007176 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G05 compound treatment 0.0017 0.24 0.89 0.0084 0.244 0.91 1.2669 0.9999 SpOx1.1_007177 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G06 compound treatment 7.0E-4 0.239 0.88 0.0114 0.247 0.92 1.2721 0.9998 SpOx1.1_007178 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G07 compound treatment 0.0297 0.268 0.99 0.0244 0.26 0.96 1.382 0.9999 SpOx1.1_007179 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G08 compound treatment 0.0097 0.248 0.92 0.0094 0.245 0.91 1.2904 1.0 SpOx1.1_007180 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G09 compound treatment 0.0027 0.241 0.89 0.0224 0.258 0.96 1.3062 0.9993 SpOx1.1_007181 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G10 compound treatment 0.0107 0.249 0.92 0.0274 0.263 0.98 1.3402 0.9996 SpOx1.1_007182 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G11 compound treatment -0.0063 0.232 0.86 0.0174 0.253 0.94 1.2695 0.999 SpOx1.1_007183 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G12 compound treatment 0.0177 0.256 0.95 0.0064 0.242 0.9 1.3034 0.9997 SpOx1.1_007184 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G13 compound treatment 0.0157 0.254 0.94 -0.0056 0.23 0.85 1.2668 0.9989 SpOx1.1_007185 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G14 compound treatment -0.0063 0.232 0.86 0.0034 0.239 0.89 1.2328 0.9999 SpOx1.1_007186 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G15 compound treatment 0.0077 0.246 0.91 0.0124 0.248 0.92 1.293 1.0 SpOx1.1_007187 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G16 compound treatment -0.0133 0.225 0.83 -0.0046 0.231 0.86 1.1936 0.9999 SpOx1.1_007188 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G17 compound treatment 0.0117 0.25 0.92 0.0084 0.244 0.91 1.293 0.9999 SpOx1.1_007189 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G18 compound treatment 0.0027 0.241 0.89 0.0174 0.253 0.94 1.2931 0.9997 SpOx1.1_007190 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G19 compound treatment 0.0207 0.259 0.96 -6.0E-4 0.235 0.87 1.293 0.9989 SpOx1.1_007191 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G20 compound treatment -0.0203 0.218 0.81 0.0174 0.253 0.94 1.2329 0.9971 2141864 SpOx1.1_007192 OCCOc1cccc(c1)[C@@H]2N3[C@H]([C@H](C(=O)NCc4nc5ccccc5[nH]4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G21 compound treatment 7.0E-4 0.239 0.88 0.0024 0.238 0.88 1.2485 1.0 SpOx1.1_007193 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G22 compound treatment -3.0E-4 0.238 0.88 0.0134 0.249 0.92 1.2747 0.9997 SpOx1.1_007194 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G23 mock treatment -0.0113 0.227 0.84 -0.0016 0.234 0.87 1.2067 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 G24 mock treatment -0.4666 -0.229 -0.85 -0.468 -0.232 -0.86 -1.2058 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H01 compound treatment 0.0067 0.245 0.9 -0.0076 0.228 0.85 1.238 0.9994 SpOx1.1_007195 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H02 compound treatment -0.0073 0.231 0.85 0.0204 0.256 0.95 1.2748 0.9986 SpOx1.1_007196 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H03 compound treatment 0.0047 0.243 0.9 0.0014 0.237 0.88 1.2564 0.9999 SpOx1.1_007197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H04 compound treatment -3.0E-4 0.238 0.88 0.0044 0.24 0.89 1.2511 1.0 SpOx1.1_007198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H05 compound treatment 7.0E-4 0.239 0.88 0.0084 0.244 0.91 1.2642 0.9999 SpOx1.1_007199 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H06 compound treatment -0.0013 0.237 0.88 -6.0E-4 0.235 0.87 1.2354 1.0 SpOx1.1_007200 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H07 compound treatment 0.0037 0.242 0.89 0.0204 0.256 0.95 1.3035 0.9995 SpOx1.1_007201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H08 compound treatment -0.0123 0.226 0.83 0.0014 0.237 0.88 1.2119 0.9997 SpOx1.1_007202 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H09 compound treatment 0.0077 0.246 0.91 0.0054 0.241 0.89 1.2747 1.0 SpOx1.1_007203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H10 compound treatment 7.0E-4 0.239 0.88 0.0274 0.263 0.98 1.314 0.9988 SpOx1.1_007204 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H11 compound treatment 0.0037 0.242 0.89 -0.0046 0.231 0.86 1.238 0.9998 SpOx1.1_007205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H12 compound treatment 0.0027 0.241 0.89 -0.0056 0.23 0.85 1.2328 0.9998 SpOx1.1_007206 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H13 compound treatment 0.0097 0.248 0.92 -0.0146 0.221 0.82 1.2275 0.9985 SpOx1.1_007207 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H14 compound treatment 0.0327 0.271 1.0 0.0404 0.276 1.02 1.4318 0.9999 SpOx1.1_007208 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H15 compound treatment 0.0037 0.242 0.89 0.0104 0.246 0.91 1.2773 0.9999 SpOx1.1_007209 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H16 compound treatment -0.0033 0.235 0.87 0.0034 0.239 0.89 1.2407 0.9999 SpOx1.1_007210 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H17 compound treatment 0.0047 0.243 0.9 0.0054 0.241 0.89 1.2668 1.0 SpOx1.1_007211 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H18 compound treatment -0.0013 0.237 0.88 0.0074 0.243 0.9 1.2564 0.9999 SpOx1.1_007212 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H19 compound treatment 0.0177 0.256 0.95 0.0164 0.252 0.93 1.3297 1.0 SpOx1.1_007213 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H20 compound treatment -3.0E-4 0.238 0.88 0.0084 0.244 0.91 1.2616 0.9999 SpOx1.1_007214 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H21 compound treatment -0.0013 0.237 0.88 0.0044 0.24 0.89 1.2485 1.0 SpOx1.1_007215 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H22 compound treatment 0.0087 0.247 0.91 0.0134 0.249 0.92 1.2983 1.0 SpOx1.1_007216 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H23 mock treatment -0.0103 0.228 0.84 0.0084 0.244 0.91 1.2355 0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 H24 mock treatment -0.4706 -0.233 -0.86 -0.467 -0.231 -0.86 -1.2137 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I01 compound treatment 0.0217 0.26 0.96 0.0164 0.252 0.93 1.3401 0.9999 SpOx1.1_007217 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I02 compound treatment 0.0057 0.244 0.9 0.0144 0.25 0.93 1.293 0.9999 SpOx1.1_007218 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I03 compound treatment 0.0497 0.288 1.06 0.0354 0.271 1.01 1.4631 0.9996 SpOx1.1_007219 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I04 compound treatment -0.0043 0.234 0.86 -0.0056 0.23 0.85 1.2145 1.0 SpOx1.1_007220 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I05 compound treatment 0.0047 0.243 0.9 0.0204 0.256 0.95 1.3061 0.9996 SpOx1.1_007221 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I06 compound treatment -0.0013 0.237 0.88 0.0074 0.243 0.9 1.2564 0.9999 SpOx1.1_007222 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I07 compound treatment 0.0157 0.254 0.94 0.0204 0.256 0.95 1.3349 1.0 SpOx1.1_007223 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I08 compound treatment 0.0047 0.243 0.9 4.0E-4 0.236 0.88 1.2537 0.9999 SpOx1.1_007224 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I09 compound treatment 0.0297 0.268 0.99 -0.0086 0.227 0.84 1.2955 0.9968 SpOx1.1_007225 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I10 compound treatment 0.0117 0.25 0.92 0.0214 0.257 0.95 1.3271 0.9999 SpOx1.1_007226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I11 compound treatment 0.0197 0.258 0.95 0.0334 0.269 1.0 1.3794 0.9997 SpOx1.1_007227 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I12 compound treatment 0.0127 0.251 0.93 0.0174 0.253 0.94 1.3192 1.0 SpOx1.1_007228 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I13 compound treatment 0.0207 0.259 0.96 0.0284 0.264 0.98 1.3689 0.9999 SpOx1.1_007229 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I14 compound treatment -0.0203 0.218 0.81 0.0064 0.242 0.9 1.2041 0.9985 SpOx1.1_007230 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I15 compound treatment -0.0133 0.225 0.83 0.0034 0.239 0.89 1.2145 0.9995 SpOx1.1_007231 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I16 compound treatment -0.0263 0.212 0.78 -0.0026 0.233 0.86 1.1648 0.9988 SpOx1.1_007232 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I17 compound treatment 0.0067 0.245 0.9 -0.0076 0.228 0.85 1.238 0.9994 SpOx1.1_007233 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I18 compound treatment 0.0207 0.259 0.96 0.0064 0.242 0.9 1.3113 0.9995 SpOx1.1_007234 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I19 compound treatment -0.0033 0.235 0.87 0.0144 0.25 0.93 1.2695 0.9995 SpOx1.1_007235 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I20 compound treatment -0.0053 0.233 0.86 0.0094 0.245 0.91 1.2512 0.9996 SpOx1.1_007236 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I21 compound treatment 0.0197 0.258 0.95 4.0E-4 0.236 0.88 1.293 0.9991 SpOx1.1_007237 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I22 compound treatment 0.0117 0.25 0.92 0.0244 0.26 0.96 1.3349 0.9998 SpOx1.1_007238 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I23 mock treatment 0.0017 0.24 0.89 0.0014 0.237 0.88 1.2485 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 I24 mock treatment -0.4706 -0.233 -0.86 -0.467 -0.231 -0.86 -1.2137 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J01 compound treatment 0.0057 0.244 0.9 0.0044 0.24 0.89 1.2668 1.0 SpOx1.1_007239 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J02 compound treatment 0.0037 0.242 0.89 -0.0056 0.23 0.85 1.2354 0.9997 SpOx1.1_007240 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J03 compound treatment 0.0017 0.24 0.89 -0.0106 0.225 0.83 1.2171 0.9995 SpOx1.1_007241 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J04 compound treatment 0.0097 0.248 0.92 0.0044 0.24 0.89 1.2773 0.9999 SpOx1.1_007242 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J05 compound treatment -0.0033 0.235 0.87 0.0064 0.242 0.9 1.2485 0.9999 SpOx1.1_007243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J06 compound treatment -0.0023 0.236 0.87 0.0214 0.257 0.95 1.2905 0.999 SpOx1.1_007244 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J07 compound treatment 0.0017 0.24 0.89 4.0E-4 0.236 0.88 1.2459 1.0 SpOx1.1_007245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J08 compound treatment -0.0033 0.235 0.87 -0.0056 0.23 0.85 1.2171 1.0 SpOx1.1_007246 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J09 compound treatment 0.0057 0.244 0.9 0.0084 0.244 0.91 1.2773 1.0 SpOx1.1_007247 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J10 compound treatment -0.0063 0.232 0.86 0.0084 0.244 0.91 1.2459 0.9996 SpOx1.1_007248 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J11 compound treatment -0.0033 0.235 0.87 0.0184 0.254 0.94 1.28 0.9992 SpOx1.1_007249 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J12 compound treatment -0.0063 0.232 0.86 0.0104 0.246 0.91 1.2512 0.9995 SpOx1.1_007250 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J13 compound treatment -0.0233 0.215 0.79 -0.0136 0.222 0.82 1.1438 0.9998 SpOx1.1_007251 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J14 compound treatment -0.0103 0.228 0.84 0.0074 0.243 0.9 1.2329 0.9994 SpOx1.1_007252 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J15 compound treatment -0.0043 0.234 0.86 -0.0166 0.219 0.81 1.1857 0.9995 SpOx1.1_007253 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J16 compound treatment -0.0133 0.225 0.83 -0.0226 0.213 0.79 1.1464 0.9997 SpOx1.1_007254 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J17 compound treatment 0.0097 0.248 0.92 -0.0036 0.232 0.86 1.2563 0.9995 SpOx1.1_007255 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J18 compound treatment -0.0033 0.235 0.87 0.0044 0.24 0.89 1.2433 0.9999 SpOx1.1_007256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J19 compound treatment 0.0027 0.241 0.89 0.0104 0.246 0.91 1.2747 0.9999 SpOx1.1_007257 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J20 compound treatment 0.0137 0.252 0.93 0.0144 0.25 0.93 1.314 1.0 SpOx1.1_007258 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J21 compound treatment 0.0027 0.241 0.89 0.0164 0.252 0.93 1.2904 0.9997 SpOx1.1_007259 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J22 compound treatment 0.0167 0.255 0.94 -0.0016 0.234 0.87 1.2799 0.9992 SpOx1.1_007260 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J23 mock treatment -0.0113 0.227 0.84 -0.0096 0.226 0.84 1.1857 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 J24 mock treatment -0.4676 -0.23 -0.85 -0.467 -0.231 -0.86 -1.2058 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K01 compound treatment 0.0257 0.264 0.98 0.0134 0.249 0.92 1.3427 0.9996 SpOx1.1_007261 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K02 compound treatment 0.0107 0.249 0.92 0.0044 0.24 0.89 1.2799 0.9999 SpOx1.1_007262 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K03 compound treatment 0.0267 0.265 0.98 0.0124 0.248 0.92 1.3427 0.9995 SpOx1.1_007263 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K04 compound treatment 0.0017 0.24 0.89 0.0084 0.244 0.91 1.2669 0.9999 SpOx1.1_007264 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K05 compound treatment 0.0117 0.25 0.92 0.0174 0.253 0.94 1.3166 1.0 SpOx1.1_007265 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K06 compound treatment 0.0107 0.249 0.92 4.0E-4 0.236 0.88 1.2694 0.9997 SpOx1.1_007266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K07 compound treatment -0.0213 0.217 0.8 0.0294 0.265 0.98 1.2617 0.9949 2141611 SpOx1.1_007267 OCCOc1cccc(c1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4nc5ccccc5[nH]4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K08 compound treatment -0.0013 0.237 0.88 0.0174 0.253 0.94 1.2826 0.9994 SpOx1.1_007268 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K09 compound treatment -0.0183 0.22 0.81 -0.0076 0.228 0.85 1.1726 0.9998 SpOx1.1_007269 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K10 compound treatment 0.0077 0.246 0.91 0.0164 0.252 0.93 1.3035 0.9999 SpOx1.1_007270 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K11 compound treatment -3.0E-4 0.238 0.88 0.0144 0.25 0.93 1.2773 0.9996 SpOx1.1_007271 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K12 compound treatment -0.0053 0.233 0.86 0.0034 0.239 0.89 1.2355 0.9999 SpOx1.1_007272 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K13 compound treatment -0.0163 0.222 0.82 0.0134 0.249 0.92 1.2329 0.9982 SpOx1.1_007273 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K14 compound treatment 0.0127 0.251 0.93 0.0104 0.246 0.91 1.3009 1.0 SpOx1.1_007274 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K15 compound treatment 0.0017 0.24 0.89 -0.0026 0.233 0.86 1.238 0.9999 SpOx1.1_007275 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K16 compound treatment 0.0107 0.249 0.92 0.0144 0.25 0.93 1.3061 1.0 SpOx1.1_007276 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K17 compound treatment -0.0013 0.237 0.88 -6.0E-4 0.235 0.87 1.2354 1.0 SpOx1.1_007277 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K18 compound treatment 0.0097 0.248 0.92 -0.0066 0.229 0.85 1.2485 0.9993 SpOx1.1_007278 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K19 compound treatment 0.0037 0.242 0.89 0.0074 0.243 0.9 1.2694 1.0 SpOx1.1_007279 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K20 compound treatment -0.0183 0.22 0.81 0.0084 0.244 0.91 1.2145 0.9986 SpOx1.1_007280 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K21 compound treatment -3.0E-4 0.238 0.88 -0.0056 0.23 0.85 1.225 0.9999 SpOx1.1_007281 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K22 compound treatment 0.0027 0.241 0.89 0.0114 0.247 0.92 1.2773 0.9999 SpOx1.1_007282 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K23 mock treatment -0.0113 0.227 0.84 -0.0026 0.233 0.86 1.204 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 K24 mock treatment -0.4726 -0.235 -0.87 -0.467 -0.231 -0.86 -1.2189 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L01 compound treatment 0.0027 0.241 0.89 0.0204 0.256 0.95 1.3009 0.9995 SpOx1.1_007283 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L02 compound treatment 0.0287 0.267 0.99 0.0334 0.269 1.0 1.403 1.0 SpOx1.1_007284 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L03 compound treatment 0.0137 0.252 0.93 0.0264 0.262 0.97 1.3454 0.9998 SpOx1.1_007285 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L04 compound treatment 0.0217 0.26 0.96 0.0204 0.256 0.95 1.3506 1.0 SpOx1.1_007286 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L05 compound treatment 0.0197 0.258 0.95 0.0244 0.26 0.96 1.3558 1.0 SpOx1.1_007287 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L06 compound treatment 0.0187 0.257 0.95 0.0104 0.246 0.91 1.3165 0.9998 2141908 SpOx1.1_007288 OCCOc1cccc(c1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4nc5ccccc5[nH]4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L07 compound treatment 0.0217 0.26 0.96 0.0134 0.249 0.92 1.3322 0.9998 SpOx1.1_007289 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L08 compound treatment 0.0037 0.242 0.89 0.0034 0.239 0.89 1.259 1.0 SpOx1.1_007290 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L09 compound treatment 0.0147 0.253 0.93 0.0244 0.26 0.96 1.3428 0.9999 SpOx1.1_007291 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L10 compound treatment -0.0063 0.232 0.86 0.0294 0.265 0.98 1.301 0.9977 SpOx1.1_007292 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L11 compound treatment -0.0023 0.236 0.87 0.0224 0.258 0.96 1.2931 0.9989 SpOx1.1_007293 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L12 compound treatment 0.0127 0.251 0.93 0.0224 0.258 0.96 1.3323 0.9999 2141611 SpOx1.1_007294 OCCOc1cccc(c1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4nc5ccccc5[nH]4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L13 compound treatment 0.0057 0.244 0.9 0.0234 0.259 0.96 1.3166 0.9995 SpOx1.1_007295 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L14 compound treatment 0.0157 0.254 0.94 0.0284 0.264 0.98 1.3559 0.9998 SpOx1.1_007296 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L15 compound treatment 0.0137 0.252 0.93 0.0074 0.243 0.9 1.2956 0.9999 SpOx1.1_007297 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L16 compound treatment 0.0037 0.242 0.89 0.0164 0.252 0.93 1.293 0.9998 SpOx1.1_007298 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L17 compound treatment 0.0047 0.243 0.9 0.0274 0.263 0.98 1.3245 0.9991 SpOx1.1_007299 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L18 compound treatment 0.0257 0.264 0.98 0.0124 0.248 0.92 1.3401 0.9996 SpOx1.1_007300 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L19 compound treatment 0.0217 0.26 0.96 0.0284 0.264 0.98 1.3715 1.0 SpOx1.1_007301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L20 compound treatment 0.0197 0.258 0.95 0.0224 0.258 0.96 1.3506 1.0 SpOx1.1_007302 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L21 compound treatment 0.0087 0.247 0.91 0.0264 0.262 0.97 1.3323 0.9995 SpOx1.1_007303 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L22 compound treatment 0.0257 0.264 0.98 0.0394 0.275 1.02 1.4108 0.9997 SpOx1.1_007304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L23 mock treatment 0.0137 0.252 0.93 0.0214 0.257 0.95 1.3323 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 L24 mock treatment -0.4716 -0.234 -0.86 -0.469 -0.233 -0.86 -1.2215 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M01 compound treatment 0.0317 0.27 1.0 0.0184 0.254 0.94 1.3715 0.9996 SpOx1.1_007305 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M02 compound treatment 0.0367 0.275 1.02 0.0124 0.248 0.92 1.3688 0.9988 SpOx1.1_007306 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M03 compound treatment 0.0407 0.279 1.03 0.0314 0.267 0.99 1.4291 0.9998 SpOx1.1_007307 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M04 compound treatment 0.0377 0.276 1.02 0.0304 0.266 0.99 1.4186 0.9999 SpOx1.1_007308 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M05 compound treatment 0.0497 0.288 1.06 0.0354 0.271 1.01 1.4631 0.9996 SpOx1.1_007309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M06 compound treatment 0.0267 0.265 0.98 0.0354 0.271 1.01 1.403 0.9999 SpOx1.1_007310 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M07 compound treatment 0.0247 0.263 0.97 0.0254 0.261 0.97 1.3715 1.0 SpOx1.1_007311 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M08 compound treatment 0.0177 0.256 0.95 0.0264 0.262 0.97 1.3558 0.9999 SpOx1.1_007312 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M09 compound treatment 0.0137 0.252 0.93 0.0244 0.26 0.96 1.3401 0.9998 SpOx1.1_007313 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M10 compound treatment 0.0117 0.25 0.92 0.0144 0.25 0.93 1.3087 1.0 SpOx1.1_007314 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M11 compound treatment 0.0247 0.263 0.97 0.0174 0.253 0.94 1.3505 0.9999 SpOx1.1_007315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M12 compound treatment 0.0157 0.254 0.94 0.0014 0.237 0.88 1.2851 0.9995 SpOx1.1_007316 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M13 compound treatment -0.0093 0.229 0.85 0.0134 0.249 0.92 1.2512 0.999 SpOx1.1_007317 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M14 compound treatment 0.0107 0.249 0.92 0.0304 0.266 0.99 1.348 0.9994 SpOx1.1_007318 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M15 compound treatment 0.0177 0.256 0.95 0.0034 0.239 0.89 1.2956 0.9995 SpOx1.1_007319 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M16 compound treatment 0.0057 0.244 0.9 -0.0036 0.232 0.86 1.2459 0.9997 SpOx1.1_007320 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M17 compound treatment 0.0087 0.247 0.91 0.0284 0.264 0.98 1.3376 0.9994 SpOx1.1_007321 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M18 compound treatment 0.0267 0.265 0.98 0.0344 0.27 1.0 1.4003 0.9999 SpOx1.1_007322 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M19 compound treatment 0.0247 0.263 0.97 0.0244 0.26 0.96 1.3689 1.0 SpOx1.1_007323 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M20 compound treatment 0.0037 0.242 0.89 0.0214 0.257 0.95 1.3062 0.9995 SpOx1.1_007324 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M21 compound treatment 0.0207 0.259 0.96 0.0324 0.268 0.99 1.3794 0.9998 SpOx1.1_007325 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M22 compound treatment 0.0227 0.261 0.96 0.0304 0.266 0.99 1.3794 0.9999 SpOx1.1_007326 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M23 mock treatment 0.0097 0.248 0.92 0.0084 0.244 0.91 1.2878 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 M24 mock treatment -0.4706 -0.233 -0.86 -0.468 -0.232 -0.86 -1.2163 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N01 compound treatment -0.0103 0.228 0.84 0.0124 0.248 0.92 1.246 0.999 SpOx1.1_007327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N02 compound treatment -0.0013 0.237 0.88 0.0014 0.237 0.88 1.2407 1.0 SpOx1.1_007328 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N03 compound treatment 0.0217 0.26 0.96 -0.0056 0.23 0.85 1.2824 0.9983 SpOx1.1_007329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N04 compound treatment -3.0E-4 0.238 0.88 0.0044 0.24 0.89 1.2511 1.0 SpOx1.1_007330 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N05 compound treatment 0.0157 0.254 0.94 0.0154 0.251 0.93 1.3218 1.0 SpOx1.1_007331 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N06 compound treatment 0.0067 0.245 0.9 0.0174 0.253 0.94 1.3035 0.9998 SpOx1.1_007332 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N07 compound treatment -0.0113 0.227 0.84 0.0084 0.244 0.91 1.2329 0.9993 SpOx1.1_007333 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N08 compound treatment -0.0263 0.212 0.78 0.0154 0.251 0.93 1.212 0.9963 SpOx1.1_007334 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N09 compound treatment -0.0353 0.203 0.75 -0.0156 0.22 0.82 1.1072 0.9991 SpOx1.1_007335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N10 compound treatment 0.0117 0.25 0.92 0.0204 0.256 0.95 1.3244 0.9999 SpOx1.1_007336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N11 compound treatment -0.0023 0.236 0.87 4.0E-4 0.236 0.88 1.2354 1.0 SpOx1.1_007337 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N12 compound treatment 0.0097 0.248 0.92 0.0114 0.247 0.92 1.2956 1.0 SpOx1.1_007338 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N13 compound treatment 0.0107 0.249 0.92 0.0164 0.252 0.93 1.3113 1.0 SpOx1.1_007339 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N14 compound treatment 0.0137 0.252 0.93 0.0044 0.24 0.89 1.2878 0.9998 SpOx1.1_007340 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N15 compound treatment -0.0023 0.236 0.87 0.0234 0.259 0.96 1.2957 0.9988 SpOx1.1_007341 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N16 compound treatment 0.0107 0.249 0.92 0.0174 0.253 0.94 1.314 0.9999 SpOx1.1_007342 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N17 compound treatment -0.0023 0.236 0.87 0.0024 0.238 0.88 1.2407 1.0 SpOx1.1_007343 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N18 compound treatment 0.0107 0.249 0.92 0.0184 0.254 0.94 1.3166 0.9999 SpOx1.1_007344 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N19 compound treatment -0.0053 0.233 0.86 0.0124 0.248 0.92 1.259 0.9994 SpOx1.1_007345 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N20 compound treatment 0.0027 0.241 0.89 0.0214 0.257 0.95 1.3035 0.9994 SpOx1.1_007346 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N21 compound treatment 0.0227 0.261 0.96 0.0244 0.26 0.96 1.3637 1.0 SpOx1.1_007347 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N22 compound treatment 0.0137 0.252 0.93 0.0214 0.257 0.95 1.3323 0.9999 SpOx1.1_007348 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N23 mock treatment 0.0047 0.243 0.9 0.0034 0.239 0.89 1.2616 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 N24 mock treatment -0.4736 -0.236 -0.87 -0.468 -0.232 -0.86 -1.2241 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O01 compound treatment 0.0047 0.243 0.9 0.0184 0.254 0.94 1.3009 0.9997 SpOx1.1_007349 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O02 compound treatment 0.0337 0.272 1.0 0.0214 0.257 0.95 1.3846 0.9997 SpOx1.1_007350 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O03 compound treatment 0.0207 0.259 0.96 0.0074 0.243 0.9 1.3139 0.9996 SpOx1.1_007351 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O04 compound treatment 0.0277 0.266 0.98 0.0174 0.253 0.94 1.3584 0.9997 SpOx1.1_007352 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O05 compound treatment 0.0287 0.267 0.99 0.0144 0.25 0.93 1.3531 0.9995 SpOx1.1_007353 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O06 compound treatment 0.0207 0.259 0.96 0.0104 0.246 0.91 1.3217 0.9997 SpOx1.1_007354 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O07 compound treatment 0.0157 0.254 0.94 0.0254 0.261 0.97 1.348 0.9999 SpOx1.1_007355 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O08 compound treatment 0.0247 0.263 0.97 0.0144 0.25 0.93 1.3427 0.9997 SpOx1.1_007356 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O09 compound treatment 0.0237 0.262 0.97 0.0284 0.264 0.98 1.3768 1.0 SpOx1.1_007357 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O10 compound treatment 0.0117 0.25 0.92 0.0104 0.246 0.91 1.2982 1.0 SpOx1.1_007358 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O11 compound treatment 0.0157 0.254 0.94 0.0104 0.246 0.91 1.3087 0.9999 SpOx1.1_007359 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O12 compound treatment 0.0097 0.248 0.92 -0.0026 0.233 0.86 1.259 0.9996 SpOx1.1_007360 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O13 compound treatment 0.0037 0.242 0.89 0.0174 0.253 0.94 1.2957 0.9997 SpOx1.1_007361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O14 compound treatment 0.0097 0.248 0.92 0.0164 0.252 0.93 1.3087 0.9999 SpOx1.1_007362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O15 compound treatment 0.0487 0.287 1.06 0.0334 0.269 1.0 1.4552 0.9995 SpOx1.1_007363 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O16 compound treatment 0.0027 0.241 0.89 0.0174 0.253 0.94 1.2931 0.9997 SpOx1.1_007364 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O17 compound treatment 0.0047 0.243 0.9 0.0324 0.268 0.99 1.3376 0.9987 SpOx1.1_007365 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O18 compound treatment 0.0177 0.256 0.95 0.0204 0.256 0.95 1.3401 1.0 SpOx1.1_007366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O19 compound treatment 0.0057 0.244 0.9 0.0234 0.259 0.96 1.3166 0.9995 SpOx1.1_007367 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O20 compound treatment 0.0167 0.255 0.94 0.0154 0.251 0.93 1.3244 1.0 SpOx1.1_007368 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O21 compound treatment 0.0257 0.264 0.98 0.0154 0.251 0.93 1.3479 0.9997 SpOx1.1_007369 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O22 compound treatment 0.0207 0.259 0.96 0.0244 0.26 0.96 1.3585 1.0 SpOx1.1_007370 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O23 mock treatment 0.0107 0.249 0.92 0.0044 0.24 0.89 1.2799 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 O24 mock treatment -0.4746 -0.237 -0.87 -0.469 -0.233 -0.86 -1.2294 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P01 compound treatment -0.0103 0.228 0.84 -0.0086 0.227 0.84 1.1909 1.0 SpOx1.1_007371 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P02 compound treatment -0.0083 0.23 0.85 -0.0016 0.234 0.87 1.2145 0.9999 SpOx1.1_007372 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P03 compound treatment 0.0027 0.241 0.89 0.0134 0.249 0.92 1.2825 0.9998 SpOx1.1_007373 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P04 compound treatment -0.0023 0.236 0.87 -0.0076 0.228 0.85 1.2145 0.9999 SpOx1.1_007374 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P05 compound treatment 0.0047 0.243 0.9 -0.0096 0.226 0.84 1.2275 0.9994 SpOx1.1_007375 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P06 compound treatment 0.0047 0.243 0.9 -0.0046 0.231 0.86 1.2406 0.9997 SpOx1.1_007376 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P07 compound treatment -0.0193 0.219 0.81 -0.0126 0.223 0.83 1.1569 0.9999 SpOx1.1_007377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P08 compound treatment -0.0043 0.234 0.86 0.0104 0.246 0.91 1.2564 0.9996 SpOx1.1_007378 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P09 compound treatment -0.0053 0.233 0.86 -0.0126 0.223 0.83 1.1935 0.9998 SpOx1.1_007379 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P10 compound treatment -0.0023 0.236 0.87 0.0054 0.241 0.89 1.2485 0.9999 SpOx1.1_007380 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P11 compound treatment -0.0253 0.213 0.79 -0.0256 0.21 0.78 1.1072 1.0 SpOx1.1_007381 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P12 compound treatment -0.0123 0.226 0.83 4.0E-4 0.236 0.88 1.2093 0.9997 SpOx1.1_007382 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P13 compound treatment -0.0083 0.23 0.85 -0.0116 0.224 0.83 1.1883 0.9999 SpOx1.1_007383 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P14 compound treatment 0.0017 0.24 0.89 -0.0066 0.229 0.85 1.2276 0.9998 SpOx1.1_007384 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P15 compound treatment -0.0173 0.221 0.82 4.0E-4 0.236 0.88 1.1962 0.9994 SpOx1.1_007385 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P16 compound treatment -0.0173 0.221 0.82 -0.0146 0.221 0.82 1.1569 1.0 SpOx1.1_007386 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P17 compound treatment 0.0077 0.246 0.91 -0.0016 0.234 0.87 1.2563 0.9997 SpOx1.1_007387 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P18 compound treatment -0.0153 0.223 0.82 0.0144 0.25 0.93 1.2381 0.9983 SpOx1.1_007388 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P19 compound treatment -0.0123 0.226 0.83 4.0E-4 0.236 0.88 1.2093 0.9997 SpOx1.1_007389 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P20 compound treatment -3.0E-4 0.238 0.88 0.0064 0.242 0.9 1.2564 0.9999 SpOx1.1_007390 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P21 compound treatment -0.0043 0.234 0.86 0.0184 0.254 0.94 1.2774 0.9991 SpOx1.1_007391 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P22 compound treatment -0.0103 0.228 0.84 0.0084 0.244 0.91 1.2355 0.9994 SpOx1.1_007392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P23 mock treatment -0.0123 0.226 0.83 0.0014 0.237 0.88 1.2119 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1299 P24 mock treatment -0.4736 -0.236 -0.87 -0.468 -0.232 -0.86 -1.2241 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A01 compound treatment -0.0921 0.145 0.54 -0.0767 0.159 0.59 0.7957 0.9989 SpOx1.1_007745 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A02 compound treatment -0.0319 0.205 0.76 -0.0277 0.208 0.77 1.0816 1.0 SpOx1.1_007746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A03 compound treatment -0.0859 0.151 0.56 -0.0717 0.164 0.61 0.825 0.9991 SpOx1.1_007747 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A04 compound treatment -0.0981 0.139 0.51 -0.0797 0.156 0.58 0.7723 0.9983 SpOx1.1_007748 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A05 compound treatment -0.0899 0.147 0.54 -0.0797 0.156 0.58 0.7937 0.9995 SpOx1.1_007749 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A06 compound treatment -0.0469 0.19 0.7 -0.0447 0.191 0.71 0.9977 1.0 SpOx1.1_007750 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A07 compound treatment -0.0419 0.195 0.72 -0.0427 0.193 0.72 1.016 1.0 SpOx1.1_007751 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A08 compound treatment -0.0779 0.159 0.59 -0.0707 0.165 0.61 0.8486 0.9998 SpOx1.1_007752 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A09 compound treatment -0.1171 0.12 0.44 -0.1091 0.127 0.47 0.6455 0.9996 SpOx1.1_007753 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A10 compound treatment -0.0779 0.159 0.59 -0.0737 0.162 0.6 0.8407 1.0 SpOx1.1_007754 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A11 compound treatment -0.0349 0.202 0.75 -0.0377 0.198 0.73 1.0475 1.0 SpOx1.1_007755 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A12 compound treatment -0.0499 0.187 0.69 -0.0447 0.191 0.71 0.9899 0.9999 SpOx1.1_007756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A13 compound treatment -0.1059 0.131 0.49 -0.1047 0.131 0.49 0.6863 1.0 SpOx1.1_007757 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A14 compound treatment -0.0659 0.171 0.63 -0.0577 0.178 0.66 0.914 0.9998 SpOx1.1_007758 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A15 compound treatment -0.0379 0.199 0.74 -0.0357 0.2 0.74 1.0448 1.0 SpOx1.1_007759 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A16 compound treatment -0.0779 0.159 0.59 -0.0827 0.153 0.57 0.8171 0.9998 SpOx1.1_007760 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A17 compound treatment -0.1371 0.1 0.37 -0.1411 0.0946 0.35 0.5093 0.9996 SpOx1.1_007761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A18 compound treatment -0.1269 0.11 0.41 -0.1247 0.111 0.41 0.5789 1.0 SpOx1.1_007762 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A19 compound treatment -0.0839 0.153 0.57 -0.0787 0.157 0.58 0.8119 0.9999 SpOx1.1_007763 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A20 compound treatment -0.0889 0.148 0.55 -0.0911 0.145 0.54 0.7663 0.9999 SpOx1.1_007764 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A21 compound treatment -0.0941 0.143 0.53 -0.0961 0.14 0.52 0.7396 0.9999 SpOx1.1_007765 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A22 compound treatment -0.1091 0.128 0.47 -0.1021 0.134 0.49 0.6847 0.9998 SpOx1.1_007766 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A23 mock treatment -0.0779 0.159 0.59 -0.0741 0.162 0.6 0.8396 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 A24 mock treatment -0.4668 -0.23 -0.85 -0.4656 -0.23 -0.85 -1.203 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B01 compound treatment -0.0079 0.229 0.85 -0.0037 0.232 0.86 1.2071 1.0 SpOx1.1_007767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B02 compound treatment -0.0039 0.233 0.86 -0.0017 0.234 0.87 1.2228 1.0 SpOx1.1_007768 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B03 compound treatment -0.0029 0.234 0.87 0.0033 0.239 0.89 1.2385 0.9999 SpOx1.1_007769 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B04 compound treatment 0.0071 0.244 0.9 0.0093 0.245 0.91 1.2804 1.0 SpOx1.1_007770 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B05 compound treatment -9.0E-4 0.236 0.87 -0.0017 0.234 0.87 1.2307 1.0 SpOx1.1_007771 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B06 compound treatment -0.0119 0.225 0.83 -0.0087 0.227 0.84 1.1835 1.0 SpOx1.1_007772 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B07 compound treatment -0.0289 0.208 0.77 -0.0277 0.208 0.77 1.0893 1.0 SpOx1.1_007773 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B08 compound treatment 0.0101 0.247 0.91 0.0083 0.244 0.9 1.2856 1.0 SpOx1.1_007774 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B09 compound treatment -0.0029 0.234 0.87 -0.0017 0.234 0.87 1.2254 1.0 SpOx1.1_007775 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B10 compound treatment -0.0029 0.234 0.87 0.0013 0.237 0.88 1.2332 1.0 SpOx1.1_007776 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B11 compound treatment -0.0029 0.234 0.87 0.0043 0.24 0.89 1.2411 0.9999 SpOx1.1_007777 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B12 compound treatment -0.0069 0.23 0.85 -7.0E-4 0.235 0.87 1.2175 0.9999 SpOx1.1_007778 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B13 compound treatment -0.0119 0.225 0.83 -0.0097 0.226 0.84 1.1809 1.0 SpOx1.1_007779 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B14 compound treatment -0.0019 0.235 0.87 -7.0E-4 0.235 0.87 1.2307 1.0 SpOx1.1_007780 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B15 compound treatment -0.0909 0.146 0.54 -0.0847 0.151 0.56 0.7779 0.9999 SpOx1.1_007781 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B16 compound treatment -0.0159 0.221 0.82 -0.0157 0.22 0.82 1.1548 1.0 SpOx1.1_007782 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B17 compound treatment 0.0071 0.244 0.9 0.0083 0.244 0.9 1.2778 1.0 SpOx1.1_007783 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B18 compound treatment -0.0679 0.169 0.63 -0.0687 0.167 0.62 0.8799 1.0 SpOx1.1_007784 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B19 compound treatment -0.0109 0.226 0.84 -0.0117 0.224 0.83 1.1783 1.0 SpOx1.1_007785 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B20 compound treatment -0.0079 0.229 0.85 -0.0067 0.229 0.85 1.1993 1.0 SpOx1.1_007786 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B21 compound treatment -0.0029 0.234 0.87 0.0033 0.239 0.89 1.2385 0.9999 SpOx1.1_007787 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B22 compound treatment -0.0099 0.227 0.84 -0.0057 0.23 0.85 1.1967 1.0 SpOx1.1_007788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B23 mock treatment 0.0051 0.242 0.9 0.0123 0.248 0.92 1.2831 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 B24 mock treatment -0.4678 -0.231 -0.85 -0.4656 -0.23 -0.85 -1.2056 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C01 compound treatment -0.0159 0.221 0.82 -0.0057 0.23 0.85 1.181 0.9998 SpOx1.1_007789 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C02 compound treatment -0.0119 0.225 0.83 -0.0107 0.225 0.83 1.1782 1.0 SpOx1.1_007790 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C03 compound treatment -0.0169 0.22 0.81 -0.0127 0.223 0.83 1.16 1.0 SpOx1.1_007791 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C04 compound treatment -0.0089 0.228 0.84 -0.0107 0.225 0.83 1.1862 1.0 SpOx1.1_007792 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C05 compound treatment 0.0211 0.258 0.95 0.0273 0.263 0.97 1.3642 0.9999 SpOx1.1_007793 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C06 compound treatment -0.0179 0.219 0.81 -0.0067 0.229 0.85 1.1731 0.9997 SpOx1.1_007794 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C07 compound treatment -0.0219 0.215 0.8 -0.0197 0.216 0.8 1.1286 1.0 SpOx1.1_007795 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C08 compound treatment -0.0089 0.228 0.84 -0.0077 0.228 0.84 1.194 1.0 SpOx1.1_007796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C09 compound treatment -0.0099 0.227 0.84 -0.0037 0.232 0.86 1.2019 0.9999 SpOx1.1_007797 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C10 compound treatment -0.0169 0.22 0.81 -0.0167 0.219 0.81 1.1496 1.0 SpOx1.1_007798 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C11 compound treatment -0.0349 0.202 0.75 -0.0287 0.207 0.77 1.071 0.9999 SpOx1.1_007799 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C12 compound treatment -0.0019 0.235 0.87 -0.0017 0.234 0.87 1.228 1.0 SpOx1.1_007800 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C13 compound treatment -0.0389 0.198 0.73 -0.0337 0.202 0.75 1.0475 0.9999 SpOx1.1_007801 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C14 compound treatment -0.0309 0.206 0.76 -0.0297 0.206 0.76 1.0788 1.0 SpOx1.1_007802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C15 compound treatment -0.0229 0.214 0.79 -0.0247 0.211 0.78 1.1129 1.0 SpOx1.1_007803 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C16 compound treatment -0.0039 0.233 0.86 -0.0037 0.232 0.86 1.2175 1.0 SpOx1.1_007804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C17 compound treatment -0.0139 0.223 0.83 -0.0127 0.223 0.83 1.1679 1.0 SpOx1.1_007805 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C18 compound treatment -0.0119 0.225 0.83 -0.0057 0.23 0.85 1.1913 0.9999 SpOx1.1_007806 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C19 compound treatment -0.0099 0.227 0.84 -0.0117 0.224 0.83 1.181 1.0 SpOx1.1_007807 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C20 compound treatment -0.0189 0.218 0.81 -0.0167 0.219 0.81 1.1443 1.0 SpOx1.1_007808 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C21 compound treatment -0.0179 0.219 0.81 -0.0187 0.217 0.8 1.1417 1.0 SpOx1.1_007809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C22 compound treatment -0.0199 0.217 0.8 -0.0237 0.212 0.79 1.1234 0.9999 SpOx1.1_007810 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C23 mock treatment -0.0249 0.212 0.78 -0.0207 0.215 0.8 1.1182 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 C24 mock treatment -0.4678 -0.231 -0.85 -0.4666 -0.231 -0.86 -1.2082 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D01 compound treatment -0.0179 0.219 0.81 -0.0147 0.221 0.82 1.1522 1.0 SpOx1.1_007811 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D02 compound treatment -0.0259 0.211 0.78 -0.0197 0.216 0.8 1.1181 0.9999 SpOx1.1_007812 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D03 compound treatment -0.0229 0.214 0.79 -0.0177 0.218 0.81 1.1312 1.0 SpOx1.1_007813 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D04 compound treatment -0.0309 0.206 0.76 -0.0307 0.205 0.76 1.0762 1.0 SpOx1.1_007814 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D05 compound treatment -0.0249 0.212 0.78 -0.0237 0.212 0.79 1.1102 1.0 SpOx1.1_007815 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D06 compound treatment -0.0219 0.215 0.8 -0.0207 0.215 0.8 1.126 1.0 SpOx1.1_007816 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D07 compound treatment -0.0199 0.217 0.8 -0.0197 0.216 0.8 1.1338 1.0 SpOx1.1_007817 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D08 compound treatment -0.0209 0.216 0.8 0.0013 0.237 0.88 1.1862 0.9989 SpOx1.1_007818 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D09 compound treatment -0.0209 0.216 0.8 -0.0257 0.21 0.78 1.1155 0.9999 SpOx1.1_007819 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D10 compound treatment -0.0239 0.213 0.79 -0.0227 0.213 0.79 1.1155 1.0 SpOx1.1_007820 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D11 compound treatment -0.0199 0.217 0.8 -0.0247 0.211 0.78 1.1207 0.9999 SpOx1.1_007821 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D12 compound treatment -0.0189 0.218 0.81 -0.0227 0.213 0.79 1.1286 0.9999 SpOx1.1_007822 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D13 compound treatment -0.0119 0.225 0.83 -0.0077 0.228 0.84 1.1862 1.0 SpOx1.1_007823 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D14 compound treatment -0.0289 0.208 0.77 -0.0287 0.207 0.77 1.0867 1.0 SpOx1.1_007824 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D15 compound treatment -0.0219 0.215 0.8 -0.0237 0.212 0.79 1.1181 1.0 SpOx1.1_007825 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D16 compound treatment 1.0E-4 0.237 0.88 -0.0097 0.226 0.84 1.2123 0.9997 SpOx1.1_007826 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D17 compound treatment -0.0159 0.221 0.82 -0.0187 0.217 0.8 1.1469 1.0 SpOx1.1_007827 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D18 compound treatment -0.0179 0.219 0.81 -0.0117 0.224 0.83 1.16 0.9999 SpOx1.1_007828 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D19 compound treatment -0.0359 0.201 0.74 -0.0317 0.204 0.76 1.0605 1.0 SpOx1.1_007829 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D20 compound treatment -0.0579 0.179 0.66 -0.0517 0.184 0.68 0.9506 0.9999 SpOx1.1_007830 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D21 compound treatment -0.0589 0.178 0.66 -0.0537 0.182 0.67 0.9428 0.9999 SpOx1.1_007831 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D22 compound treatment 0.0201 0.257 0.95 0.0173 0.253 0.94 1.3354 1.0 SpOx1.1_007832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D23 mock treatment -0.0119 0.225 0.83 -0.0107 0.225 0.83 1.1783 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 D24 mock treatment -0.4688 -0.232 -0.86 -0.4666 -0.231 -0.86 -1.2108 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E01 compound treatment -0.0219 0.215 0.8 -0.0137 0.222 0.82 1.1443 0.9999 SpOx1.1_007833 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E02 compound treatment -0.0059 0.231 0.85 -0.0017 0.234 0.87 1.2176 1.0 SpOx1.1_007834 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E03 compound treatment -0.0109 0.226 0.84 -0.0067 0.229 0.85 1.1914 1.0 SpOx1.1_007835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E04 compound treatment -0.0049 0.232 0.86 -0.0057 0.23 0.85 1.2097 1.0 SpOx1.1_007836 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E05 compound treatment -0.0079 0.229 0.85 -0.0017 0.234 0.87 1.2124 0.9999 SpOx1.1_007837 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E06 compound treatment -0.0199 0.217 0.8 -0.0177 0.218 0.81 1.1391 1.0 SpOx1.1_007838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E07 compound treatment -0.0519 0.185 0.68 -0.0507 0.185 0.69 0.9689 1.0 SpOx1.1_007839 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E08 compound treatment 0.0051 0.242 0.9 0.0063 0.242 0.9 1.2673 1.0 SpOx1.1_007840 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E09 compound treatment 0.0031 0.24 0.89 -0.0017 0.234 0.87 1.2411 0.9999 SpOx1.1_007841 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E10 compound treatment 0.0091 0.246 0.91 0.0063 0.242 0.9 1.2778 1.0 SpOx1.1_007842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E11 compound treatment -0.0269 0.21 0.78 -0.0247 0.211 0.78 1.1024 1.0 SpOx1.1_007843 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E12 compound treatment -0.0059 0.231 0.85 -0.0037 0.232 0.86 1.2123 1.0 SpOx1.1_007844 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E13 compound treatment 0.0021 0.239 0.88 0.0043 0.24 0.89 1.2542 1.0 SpOx1.1_007845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E14 compound treatment -0.0149 0.222 0.82 -0.0167 0.219 0.81 1.1548 1.0 SpOx1.1_007846 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E15 compound treatment 0.0021 0.239 0.88 0.0073 0.243 0.9 1.2621 1.0 SpOx1.1_007847 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E16 compound treatment -0.0119 0.225 0.83 -0.0137 0.222 0.82 1.1705 1.0 SpOx1.1_007848 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E17 compound treatment -0.0159 0.221 0.82 -0.0217 0.214 0.79 1.139 0.9999 SpOx1.1_007849 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E18 compound treatment 0.0041 0.241 0.89 0.0013 0.237 0.88 1.2516 1.0 SpOx1.1_007850 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E19 compound treatment -0.0119 0.225 0.83 -0.0177 0.218 0.81 1.16 0.9999 SpOx1.1_007851 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E20 compound treatment -0.0019 0.235 0.87 3.0E-4 0.236 0.87 1.2333 1.0 SpOx1.1_007852 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E21 compound treatment -0.0039 0.233 0.86 3.0E-4 0.236 0.87 1.228 1.0 SpOx1.1_007853 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E22 compound treatment 0.0021 0.239 0.88 0.0083 0.244 0.9 1.2647 0.9999 SpOx1.1_007854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E23 mock treatment -0.0029 0.234 0.87 -0.0037 0.232 0.86 1.2202 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 E24 mock treatment -0.4678 -0.231 -0.85 -0.4676 -0.232 -0.86 -1.2108 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F01 compound treatment -0.0159 0.221 0.82 -0.0217 0.214 0.79 1.139 0.9999 SpOx1.1_007855 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F02 compound treatment -0.0059 0.231 0.85 0.0043 0.24 0.89 1.2333 0.9998 2144737 SpOx1.1_007856 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F03 compound treatment -0.0059 0.231 0.85 -0.0067 0.229 0.85 1.2045 1.0 SpOx1.1_007857 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F04 compound treatment -0.0149 0.222 0.82 -0.0117 0.224 0.83 1.1679 1.0 SpOx1.1_007858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F05 compound treatment 0.0101 0.247 0.91 0.0123 0.248 0.92 1.2961 1.0 SpOx1.1_007859 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F06 compound treatment 0.0051 0.242 0.9 0.0113 0.247 0.92 1.2804 0.9999 SpOx1.1_007860 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F07 compound treatment 0.0011 0.238 0.88 0.0013 0.237 0.88 1.2438 1.0 SpOx1.1_007861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F08 compound treatment 0.0071 0.244 0.9 0.0113 0.247 0.92 1.2856 1.0 SpOx1.1_007862 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F09 compound treatment -0.0239 0.213 0.79 -0.0207 0.215 0.8 1.1208 1.0 SpOx1.1_007863 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F10 compound treatment 0.0031 0.24 0.89 0.0053 0.241 0.89 1.2595 1.0 SpOx1.1_007864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F11 compound treatment -0.0059 0.231 0.85 -0.0087 0.227 0.84 1.1993 1.0 SpOx1.1_007865 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F12 compound treatment -0.0039 0.233 0.86 -7.0E-4 0.235 0.87 1.2255 1.0 SpOx1.1_007866 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F13 compound treatment -0.0019 0.235 0.87 3.0E-4 0.236 0.87 1.2333 1.0 SpOx1.1_007867 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F14 compound treatment -0.0159 0.221 0.82 -0.0127 0.223 0.83 1.1626 1.0 SpOx1.1_007868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F15 compound treatment -0.0189 0.218 0.81 -0.0187 0.217 0.8 1.1391 1.0 SpOx1.1_007869 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F16 compound treatment 0.0061 0.243 0.9 0.0053 0.241 0.89 1.2673 1.0 SpOx1.1_007870 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F17 compound treatment -0.0119 0.225 0.83 -0.0037 0.232 0.86 1.1967 0.9999 SpOx1.1_007871 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F18 compound treatment -0.0149 0.222 0.82 -0.0137 0.222 0.82 1.1626 1.0 SpOx1.1_007872 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F19 compound treatment 0.0071 0.244 0.9 0.0133 0.249 0.92 1.2909 0.9999 SpOx1.1_007873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F20 compound treatment -9.0E-4 0.236 0.87 0.0043 0.24 0.89 1.2463 1.0 SpOx1.1_007874 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F21 compound treatment -0.0149 0.222 0.82 -0.0167 0.219 0.81 1.1548 1.0 SpOx1.1_007875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F22 compound treatment -0.0049 0.232 0.86 -0.0047 0.231 0.86 1.2123 1.0 SpOx1.1_007876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F23 mock treatment 0.0091 0.246 0.91 0.0073 0.243 0.9 1.2804 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 F24 mock treatment -0.4688 -0.232 -0.86 -0.4676 -0.232 -0.86 -1.2134 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G01 compound treatment -0.0059 0.231 0.85 -7.0E-4 0.235 0.87 1.2202 1.0 SpOx1.1_007877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G02 compound treatment -0.0229 0.214 0.79 -0.0177 0.218 0.81 1.1312 1.0 SpOx1.1_007878 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G03 compound treatment -0.0289 0.208 0.77 -0.0257 0.21 0.78 1.0946 1.0 SpOx1.1_007879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G04 compound treatment 0.0021 0.239 0.88 0.0043 0.24 0.89 1.2543 1.0 SpOx1.1_007880 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G05 compound treatment -0.0229 0.214 0.79 -0.0207 0.215 0.8 1.1234 1.0 SpOx1.1_007881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G06 compound treatment -0.0239 0.213 0.79 -0.0187 0.217 0.8 1.126 1.0 SpOx1.1_007882 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G07 compound treatment -0.0109 0.226 0.84 -0.0117 0.224 0.83 1.1783 1.0 SpOx1.1_007883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G08 compound treatment -0.0029 0.234 0.87 -0.0027 0.233 0.86 1.2228 1.0 SpOx1.1_007884 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G09 compound treatment -0.0129 0.224 0.83 -0.0087 0.227 0.84 1.181 1.0 SpOx1.1_007885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G10 compound treatment -0.0239 0.213 0.79 -0.0227 0.213 0.79 1.1155 1.0 SpOx1.1_007886 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G11 compound treatment -0.0179 0.219 0.81 -0.0177 0.218 0.81 1.1443 1.0 SpOx1.1_007887 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G12 compound treatment -9.0E-4 0.236 0.87 3.0E-4 0.236 0.87 1.2359 1.0 SpOx1.1_007888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G13 compound treatment -0.0079 0.229 0.85 -0.0117 0.224 0.83 1.1862 0.9999 SpOx1.1_007889 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G14 compound treatment -0.0239 0.213 0.79 -0.0227 0.213 0.79 1.1155 1.0 SpOx1.1_007890 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G15 compound treatment -0.0129 0.224 0.83 -0.0147 0.221 0.82 1.1652 1.0 SpOx1.1_007891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G16 compound treatment -0.0209 0.216 0.8 -0.0167 0.219 0.81 1.1391 1.0 SpOx1.1_007892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G17 compound treatment -0.0049 0.232 0.86 -0.0037 0.232 0.86 1.2149 1.0 SpOx1.1_007893 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G18 compound treatment -0.0089 0.228 0.84 -0.0067 0.229 0.85 1.1966 1.0 SpOx1.1_007894 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G19 compound treatment -0.0139 0.223 0.83 -0.0137 0.222 0.82 1.1652 1.0 SpOx1.1_007895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G20 compound treatment -0.0329 0.204 0.76 -0.0317 0.204 0.76 1.0684 1.0 2144873 SpOx1.1_007896 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G21 compound treatment -0.0119 0.225 0.83 -0.0147 0.221 0.82 1.1678 1.0 SpOx1.1_007897 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G22 compound treatment -0.0169 0.22 0.81 -0.0197 0.216 0.8 1.1418 1.0 SpOx1.1_007898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G23 mock treatment -0.0169 0.22 0.81 -0.0147 0.221 0.82 1.1548 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 G24 mock treatment -0.4688 -0.232 -0.86 -0.4676 -0.232 -0.86 -1.2134 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H01 compound treatment -0.0099 0.227 0.84 -0.0087 0.227 0.84 1.1887 1.0 SpOx1.1_007899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H02 compound treatment -0.0279 0.209 0.77 -0.0237 0.212 0.79 1.1024 1.0 SpOx1.1_007900 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H03 compound treatment -0.0069 0.23 0.85 -0.0057 0.23 0.85 1.2045 1.0 SpOx1.1_007901 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H04 compound treatment -0.0129 0.224 0.83 -0.0107 0.225 0.83 1.1757 1.0 SpOx1.1_007902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H05 compound treatment -0.0159 0.221 0.82 -0.0067 0.229 0.85 1.1783 0.9998 SpOx1.1_007903 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H06 compound treatment -0.0089 0.228 0.84 -0.0047 0.231 0.86 1.2019 1.0 SpOx1.1_007904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H07 compound treatment -0.0029 0.234 0.87 3.0E-4 0.236 0.87 1.2307 1.0 SpOx1.1_007905 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H08 compound treatment -0.0119 0.225 0.83 -0.0147 0.221 0.82 1.1678 1.0 SpOx1.1_007906 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H09 compound treatment -0.0069 0.23 0.85 -0.0047 0.231 0.86 1.2071 1.0 SpOx1.1_007907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H10 compound treatment -0.0119 0.225 0.83 -0.0127 0.223 0.83 1.1731 1.0 SpOx1.1_007908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H11 compound treatment -0.0119 0.225 0.83 -0.0097 0.226 0.84 1.181 1.0 SpOx1.1_007909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H12 compound treatment -0.0069 0.23 0.85 -0.0047 0.231 0.86 1.2071 1.0 SpOx1.1_007910 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H13 compound treatment -0.0059 0.231 0.85 3.0E-4 0.236 0.87 1.2229 0.9999 SpOx1.1_007911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H14 compound treatment -0.0039 0.233 0.86 -0.0047 0.231 0.86 1.215 1.0 SpOx1.1_007912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H15 compound treatment -0.0129 0.224 0.83 -0.0137 0.222 0.82 1.1679 1.0 SpOx1.1_007913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H16 compound treatment -0.0119 0.225 0.83 -0.0087 0.227 0.84 1.1836 1.0 SpOx1.1_007914 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H17 compound treatment -0.0019 0.235 0.87 3.0E-4 0.236 0.87 1.2332 1.0 SpOx1.1_007915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H18 compound treatment -0.0229 0.214 0.79 -0.0217 0.214 0.79 1.1207 1.0 SpOx1.1_007916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H19 compound treatment -0.0129 0.224 0.83 -0.0167 0.219 0.81 1.16 0.9999 SpOx1.1_007917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H20 compound treatment -0.0349 0.202 0.75 -0.0327 0.203 0.75 1.0605 1.0 SpOx1.1_007918 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H21 compound treatment -0.0189 0.218 0.81 -0.0157 0.22 0.82 1.1469 1.0 SpOx1.1_007919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H22 compound treatment -0.0159 0.221 0.82 -0.0147 0.221 0.82 1.1574 1.0 SpOx1.1_007920 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H23 mock treatment -0.0169 0.22 0.81 -0.0157 0.22 0.82 1.1522 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 H24 mock treatment -0.4698 -0.233 -0.86 -0.4686 -0.233 -0.86 -1.2187 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I01 compound treatment -0.0039 0.233 0.86 0.0043 0.24 0.89 1.2385 0.9999 SpOx1.1_007921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I02 compound treatment -0.0199 0.217 0.8 -0.0167 0.219 0.81 1.1417 1.0 SpOx1.1_007922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I03 compound treatment 0.0011 0.238 0.88 0.0033 0.239 0.89 1.2489 1.0 SpOx1.1_007923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I04 compound treatment -0.0249 0.212 0.78 -0.0247 0.211 0.78 1.1076 1.0 2143753 SpOx1.1_007924 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4cccc(OCCO)c4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCN(C)Cc9ccccc9)ccc18 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I05 compound treatment -0.0049 0.232 0.86 -0.0087 0.227 0.84 1.2019 0.9999 SpOx1.1_007925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I06 compound treatment -0.0109 0.226 0.84 -0.0137 0.222 0.82 1.1731 1.0 SpOx1.1_007926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I07 compound treatment -0.0139 0.223 0.83 -0.0067 0.229 0.85 1.1836 0.9999 SpOx1.1_007927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I08 compound treatment -0.0229 0.214 0.79 -0.0187 0.217 0.8 1.1286 1.0 SpOx1.1_007928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I09 compound treatment 0.0011 0.238 0.88 0.0043 0.24 0.89 1.2516 1.0 SpOx1.1_007929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I10 compound treatment -0.0049 0.232 0.86 -0.0037 0.232 0.86 1.215 1.0 SpOx1.1_007930 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I11 compound treatment -0.0159 0.221 0.82 -0.0147 0.221 0.82 1.1574 1.0 SpOx1.1_007931 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I12 compound treatment -9.0E-4 0.236 0.87 -0.0067 0.229 0.85 1.2176 0.9999 SpOx1.1_007932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I13 compound treatment -0.0089 0.228 0.84 -0.0027 0.233 0.86 1.2071 0.9999 SpOx1.1_007933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I14 compound treatment -0.0229 0.214 0.79 -0.0187 0.217 0.8 1.1286 1.0 SpOx1.1_007934 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I15 compound treatment -0.0279 0.209 0.77 -0.0237 0.212 0.79 1.1023 1.0 SpOx1.1_007935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I16 compound treatment -0.0459 0.191 0.71 -0.0497 0.186 0.69 0.9872 0.9999 SpOx1.1_007936 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I17 compound treatment -0.0089 0.228 0.84 -0.0077 0.228 0.84 1.194 1.0 SpOx1.1_007937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I18 compound treatment -9.0E-4 0.236 0.87 -0.0017 0.234 0.87 1.2307 1.0 SpOx1.1_007938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I19 compound treatment -0.0169 0.22 0.81 -0.0147 0.221 0.82 1.1548 1.0 SpOx1.1_007939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I20 compound treatment -0.0219 0.215 0.8 -0.0257 0.21 0.78 1.1129 0.9999 SpOx1.1_007940 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I21 compound treatment 1.0E-4 0.237 0.88 0.0023 0.238 0.88 1.2438 1.0 SpOx1.1_007941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I22 compound treatment -0.0109 0.226 0.84 -0.0087 0.227 0.84 1.1862 1.0 SpOx1.1_007942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I23 mock treatment 1.0E-4 0.237 0.88 0.0023 0.238 0.88 1.2438 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 I24 mock treatment -0.4688 -0.232 -0.86 -0.4676 -0.232 -0.86 -1.2134 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J01 compound treatment -0.0189 0.218 0.81 -0.0127 0.223 0.83 1.1547 0.9999 SpOx1.1_007943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J02 compound treatment -0.0499 0.187 0.69 -0.0507 0.185 0.69 0.9742 1.0 SpOx1.1_007944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J03 compound treatment -0.0279 0.209 0.77 -0.0257 0.21 0.78 1.0972 1.0 SpOx1.1_007945 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J04 compound treatment -0.0219 0.215 0.8 -0.0197 0.216 0.8 1.1286 1.0 SpOx1.1_007946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J05 compound treatment -0.0329 0.204 0.75 -0.0307 0.205 0.76 1.071 1.0 SpOx1.1_007947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J06 compound treatment -0.0239 0.213 0.79 -0.0197 0.216 0.8 1.1234 1.0 SpOx1.1_007948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J07 compound treatment -0.0319 0.205 0.76 -0.0317 0.204 0.76 1.071 1.0 SpOx1.1_007949 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J08 compound treatment -0.0319 0.205 0.76 -0.0277 0.208 0.77 1.0815 1.0 SpOx1.1_007950 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J09 compound treatment -0.0099 0.227 0.84 -0.0037 0.232 0.86 1.2019 0.9999 SpOx1.1_007951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J10 compound treatment -0.0179 0.219 0.81 -0.0137 0.222 0.82 1.1547 1.0 SpOx1.1_007952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J11 compound treatment -0.0369 0.2 0.74 -0.0387 0.197 0.73 1.0396 1.0 SpOx1.1_007953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J12 compound treatment -0.0179 0.219 0.81 -0.0177 0.218 0.81 1.1443 1.0 SpOx1.1_007954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J13 compound treatment -0.0369 0.2 0.74 -0.0377 0.198 0.73 1.0422 1.0 SpOx1.1_007955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J14 compound treatment -0.0239 0.213 0.79 -0.0167 0.219 0.81 1.1312 0.9999 SpOx1.1_007956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J15 compound treatment -0.0109 0.226 0.84 -0.0057 0.23 0.85 1.1941 1.0 SpOx1.1_007957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J16 compound treatment -0.0199 0.217 0.8 -0.0167 0.219 0.81 1.1417 1.0 SpOx1.1_007958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J17 compound treatment -0.0089 0.228 0.84 -0.0067 0.229 0.85 1.1967 1.0 SpOx1.1_007959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J18 compound treatment -0.0119 0.225 0.83 -0.0147 0.221 0.82 1.1679 1.0 SpOx1.1_007960 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J19 compound treatment -0.0139 0.223 0.83 -0.0177 0.218 0.81 1.1547 0.9999 SpOx1.1_007961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J20 compound treatment -0.0089 0.228 0.84 -0.0117 0.224 0.83 1.1835 1.0 SpOx1.1_007962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J21 compound treatment -0.0299 0.207 0.77 -0.0137 0.222 0.82 1.1233 0.9994 SpOx1.1_007963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J22 compound treatment -0.0069 0.23 0.85 -0.0117 0.224 0.83 1.1888 0.9999 SpOx1.1_007964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J23 mock treatment -0.0149 0.222 0.82 -0.0127 0.223 0.83 1.1653 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 J24 mock treatment -0.4688 -0.232 -0.86 -0.4666 -0.231 -0.86 -1.2108 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K01 compound treatment -0.0449 0.192 0.71 -0.0597 0.176 0.65 0.9636 0.9991 SpOx1.1_007965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K02 compound treatment -0.0179 0.219 0.81 -0.0217 0.214 0.79 1.1338 0.9999 SpOx1.1_007966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K03 compound treatment -0.0279 0.209 0.77 -0.0337 0.202 0.75 1.0762 0.9999 SpOx1.1_007967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K04 compound treatment -0.1029 0.134 0.5 -0.0987 0.137 0.51 0.7098 0.9999 SpOx1.1_007968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K05 compound treatment -0.0409 0.196 0.73 -0.0377 0.198 0.73 1.0318 1.0 SpOx1.1_007969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K06 compound treatment -0.0069 0.23 0.85 -0.0057 0.23 0.85 1.2045 1.0 SpOx1.1_007970 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K07 compound treatment -0.1169 0.12 0.44 -0.1227 0.113 0.42 0.6103 0.9996 SpOx1.1_007971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K08 compound treatment -0.0289 0.208 0.77 -0.0257 0.21 0.78 1.0946 1.0 SpOx1.1_007972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K09 compound treatment -0.0339 0.203 0.75 -0.0447 0.191 0.71 1.0317 0.9996 SpOx1.1_007973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K10 compound treatment -0.0099 0.227 0.84 -0.0077 0.228 0.84 1.1914 1.0 SpOx1.1_007974 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K11 compound treatment -0.0229 0.214 0.79 -0.0227 0.213 0.79 1.1181 1.0 SpOx1.1_007975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K12 compound treatment -0.0159 0.221 0.82 -0.0137 0.222 0.82 1.16 1.0 SpOx1.1_007976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K13 compound treatment -0.0599 0.177 0.66 -0.0537 0.182 0.67 0.9402 0.9999 SpOx1.1_007977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K14 compound treatment -0.0039 0.233 0.86 -0.0027 0.233 0.86 1.2202 1.0 SpOx1.1_007978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K15 compound treatment -0.0139 0.223 0.83 -0.0087 0.227 0.84 1.1783 1.0 SpOx1.1_007979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K16 compound treatment 0.0011 0.238 0.88 -0.0067 0.229 0.85 1.2228 0.9998 SpOx1.1_007980 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K17 compound treatment -0.0559 0.181 0.67 -0.0537 0.182 0.67 0.9506 1.0 SpOx1.1_007981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K18 compound treatment -0.0109 0.226 0.84 -0.0137 0.222 0.82 1.1731 1.0 SpOx1.1_007982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K19 compound treatment -0.0209 0.216 0.8 -0.0237 0.212 0.79 1.1207 1.0 SpOx1.1_007983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K20 compound treatment -0.0439 0.193 0.71 -0.0517 0.184 0.68 0.9872 0.9997 SpOx1.1_007984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K21 compound treatment -0.0289 0.208 0.77 -0.0357 0.2 0.74 1.0684 0.9998 SpOx1.1_007985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K22 compound treatment -0.0109 0.226 0.84 -0.0127 0.223 0.83 1.1757 1.0 SpOx1.1_007986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K23 mock treatment -0.0109 0.226 0.84 -0.0117 0.224 0.83 1.1783 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 K24 mock treatment -0.4688 -0.232 -0.86 -0.4686 -0.233 -0.86 -1.2161 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L01 compound treatment -0.0339 0.203 0.75 -0.0307 0.205 0.76 1.0684 1.0 SpOx1.1_007987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L02 compound treatment -0.0159 0.221 0.82 -0.0167 0.219 0.81 1.1521 1.0 SpOx1.1_007988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L03 compound treatment -0.0179 0.219 0.81 -0.0237 0.212 0.79 1.1286 0.9999 SpOx1.1_007989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L04 compound treatment -0.0109 0.226 0.84 -0.0127 0.223 0.83 1.1757 1.0 SpOx1.1_007990 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L05 compound treatment -0.0179 0.219 0.81 -0.0187 0.217 0.8 1.1417 1.0 SpOx1.1_007991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L06 compound treatment -0.0029 0.234 0.87 -0.0037 0.232 0.86 1.2202 1.0 SpOx1.1_007992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L07 compound treatment -0.0049 0.232 0.86 -0.0017 0.234 0.87 1.2201 1.0 SpOx1.1_007993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L08 compound treatment -0.0149 0.222 0.82 -0.0127 0.223 0.83 1.1652 1.0 SpOx1.1_007994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L09 compound treatment -0.0169 0.22 0.81 -0.0137 0.222 0.82 1.1574 1.0 SpOx1.1_007995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L10 compound treatment -0.0669 0.17 0.63 -0.0657 0.17 0.63 0.8904 1.0 SpOx1.1_007996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L11 compound treatment -0.0039 0.233 0.86 -0.0047 0.231 0.86 1.215 1.0 SpOx1.1_007997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L12 compound treatment 0.0021 0.239 0.88 -0.0027 0.233 0.86 1.2359 0.9999 2142996 SpOx1.1_007998 C[C@@H](NC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L13 compound treatment -0.0089 0.228 0.84 -0.0127 0.223 0.83 1.1809 0.9999 SpOx1.1_007999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L14 compound treatment -0.0059 0.231 0.85 -0.0017 0.234 0.87 1.2175 1.0 SpOx1.1_008000 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L15 compound treatment 0.0041 0.241 0.89 0.0103 0.246 0.91 1.2751 0.9999 SpOx1.1_008001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L16 compound treatment 1.0E-4 0.237 0.88 0.0033 0.239 0.89 1.2463 1.0 SpOx1.1_008002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L17 compound treatment 0.0031 0.24 0.89 0.0023 0.238 0.88 1.2516 1.0 SpOx1.1_008003 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L18 compound treatment 0.0071 0.244 0.9 0.0043 0.24 0.89 1.2673 1.0 SpOx1.1_008004 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L19 compound treatment 0.0021 0.239 0.88 3.0E-4 0.236 0.87 1.2437 1.0 SpOx1.1_008005 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L20 compound treatment 0.0061 0.243 0.9 0.0053 0.241 0.89 1.2673 1.0 SpOx1.1_008006 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L21 compound treatment -0.0119 0.225 0.83 -0.0147 0.221 0.82 1.1678 1.0 SpOx1.1_008007 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L22 compound treatment 0.0021 0.239 0.88 -0.0017 0.234 0.87 1.2385 1.0 SpOx1.1_008008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L23 mock treatment 0.0131 0.25 0.93 0.0153 0.251 0.93 1.3118 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 L24 mock treatment -0.4678 -0.231 -0.85 -0.4666 -0.231 -0.86 -1.2082 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M01 compound treatment -0.0029 0.234 0.87 0.0063 0.242 0.9 1.2464 0.9998 SpOx1.1_008009 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M02 compound treatment -0.0808 0.156 0.58 -0.0836 0.152 0.56 0.8072 0.9999 SpOx1.1_008010 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M03 compound treatment -0.0109 0.226 0.84 -0.0087 0.227 0.84 1.1862 1.0 SpOx1.1_008011 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M04 compound treatment -0.0029 0.234 0.87 -0.0017 0.234 0.87 1.2254 1.0 SpOx1.1_008012 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M05 compound treatment -0.0199 0.217 0.8 -0.0077 0.228 0.84 1.1653 0.9997 SpOx1.1_008013 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M06 compound treatment -0.0279 0.209 0.77 -0.0147 0.221 0.82 1.126 0.9996 SpOx1.1_008014 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M07 compound treatment -0.0169 0.22 0.81 -0.0177 0.218 0.81 1.1469 1.0 SpOx1.1_008015 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M08 compound treatment -0.0169 0.22 0.81 -0.0177 0.218 0.81 1.1469 1.0 SpOx1.1_008016 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M09 compound treatment -0.0309 0.206 0.76 -0.0287 0.207 0.77 1.0815 1.0 2144024 SpOx1.1_008017 C[C@@H](NC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)O)c7cc(C#CC8(O)CCCCCC8)ccc17)c9ccccc9 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M10 compound treatment -0.0139 0.223 0.83 -0.0157 0.22 0.82 1.16 1.0 SpOx1.1_008018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M11 compound treatment -0.0059 0.231 0.85 -0.0097 0.226 0.84 1.1966 0.9999 SpOx1.1_008019 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M12 compound treatment -0.0109 0.226 0.84 -0.0127 0.223 0.83 1.1757 1.0 SpOx1.1_008020 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M13 compound treatment -0.0199 0.217 0.8 -0.0207 0.215 0.8 1.1312 1.0 SpOx1.1_008021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M14 compound treatment -0.0029 0.234 0.87 -0.0027 0.233 0.86 1.2228 1.0 SpOx1.1_008022 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M15 compound treatment -0.0059 0.231 0.85 0.0083 0.244 0.9 1.2438 0.9996 SpOx1.1_008023 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M16 compound treatment -0.0329 0.204 0.75 -0.0297 0.206 0.76 1.0736 1.0 SpOx1.1_008024 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M17 compound treatment -0.0459 0.191 0.71 -0.0427 0.193 0.72 1.0056 1.0 SpOx1.1_008025 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M18 compound treatment -0.0099 0.227 0.84 -0.0087 0.227 0.84 1.1888 1.0 SpOx1.1_008026 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M19 compound treatment 0.0101 0.247 0.91 0.0113 0.247 0.92 1.2935 1.0 SpOx1.1_008027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M20 compound treatment -0.0039 0.233 0.86 -0.0017 0.234 0.87 1.2228 1.0 SpOx1.1_008028 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M21 compound treatment 0.0041 0.241 0.89 -7.0E-4 0.235 0.87 1.2464 0.9999 SpOx1.1_008029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M22 compound treatment 1.0E-4 0.237 0.88 3.0E-4 0.236 0.87 1.2385 1.0 SpOx1.1_008030 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M23 mock treatment 0.0121 0.249 0.92 0.0123 0.248 0.92 1.3014 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 M24 mock treatment -0.4668 -0.23 -0.85 -0.4646 -0.229 -0.85 -1.2004 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N01 compound treatment -0.0259 0.211 0.78 -0.0247 0.211 0.78 1.105 1.0 SpOx1.1_008031 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N02 compound treatment -0.0249 0.212 0.78 -0.0197 0.216 0.8 1.1207 1.0 SpOx1.1_008032 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N03 compound treatment -0.0019 0.235 0.87 -7.0E-4 0.235 0.87 1.2307 1.0 SpOx1.1_008033 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N04 compound treatment -0.0069 0.23 0.85 -0.0037 0.232 0.86 1.2098 1.0 SpOx1.1_008034 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N05 compound treatment -0.0119 0.225 0.83 -0.0027 0.233 0.86 1.1993 0.9998 SpOx1.1_008035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N06 compound treatment -0.0209 0.216 0.8 -0.0107 0.225 0.83 1.1548 0.9998 SpOx1.1_008036 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N07 compound treatment -0.0209 0.216 0.8 -0.0207 0.215 0.8 1.1286 1.0 SpOx1.1_008037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N08 compound treatment -0.0389 0.198 0.73 -0.0337 0.202 0.75 1.0475 0.9999 SpOx1.1_008038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N09 compound treatment -0.0339 0.203 0.75 -0.0297 0.206 0.76 1.071 1.0 SpOx1.1_008039 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N10 compound treatment -0.0079 0.229 0.85 -0.0037 0.232 0.86 1.2071 1.0 SpOx1.1_008040 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N11 compound treatment -0.0189 0.218 0.81 -0.0157 0.22 0.82 1.1469 1.0 SpOx1.1_008041 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N12 compound treatment -0.0029 0.234 0.87 3.0E-4 0.236 0.87 1.2307 1.0 SpOx1.1_008042 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N13 compound treatment -0.0049 0.232 0.86 -0.0017 0.234 0.87 1.2202 1.0 SpOx1.1_008043 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N14 compound treatment -0.0019 0.235 0.87 -0.0017 0.234 0.87 1.228 1.0 SpOx1.1_008044 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N15 compound treatment -0.0119 0.225 0.83 -0.0117 0.224 0.83 1.1757 1.0 SpOx1.1_008045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N16 compound treatment -0.0019 0.235 0.87 0.0013 0.237 0.88 1.2359 1.0 SpOx1.1_008046 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N17 compound treatment -0.0169 0.22 0.81 -0.0117 0.224 0.83 1.1626 1.0 SpOx1.1_008047 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N18 compound treatment -0.0109 0.226 0.84 -0.0067 0.229 0.85 1.1914 1.0 SpOx1.1_008048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N19 compound treatment -0.0129 0.224 0.83 -0.0147 0.221 0.82 1.1652 1.0 SpOx1.1_008049 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N20 compound treatment -0.0039 0.233 0.86 -0.0047 0.231 0.86 1.215 1.0 SpOx1.1_008050 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N21 compound treatment 0.0161 0.253 0.94 0.0153 0.251 0.93 1.3197 1.0 SpOx1.1_008051 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N22 compound treatment 0.0021 0.239 0.88 0.0043 0.24 0.89 1.2543 1.0 SpOx1.1_008052 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N23 mock treatment 0.0141 0.251 0.93 0.0113 0.247 0.92 1.304 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 N24 mock treatment -0.4668 -0.23 -0.85 -0.4666 -0.231 -0.86 -1.2056 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O01 compound treatment -0.0229 0.214 0.79 -0.0097 0.226 0.84 1.1522 0.9996 SpOx1.1_008053 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O02 compound treatment 0.0021 0.239 0.88 0.0023 0.238 0.88 1.249 1.0 SpOx1.1_008054 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O03 compound treatment -0.0019 0.235 0.87 -7.0E-4 0.235 0.87 1.2307 1.0 SpOx1.1_008055 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O04 compound treatment 0.0011 0.238 0.88 -7.0E-4 0.235 0.87 1.2385 1.0 SpOx1.1_008056 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O05 compound treatment 0.0131 0.25 0.93 0.0123 0.248 0.92 1.3039 1.0 SpOx1.1_008057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O06 compound treatment 0.0071 0.244 0.9 0.0083 0.244 0.9 1.2778 1.0 SpOx1.1_008058 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O07 compound treatment -0.0249 0.212 0.78 -0.0257 0.21 0.78 1.105 1.0 SpOx1.1_008059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O08 compound treatment 0.0111 0.248 0.92 0.0103 0.246 0.91 1.2935 1.0 SpOx1.1_008060 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O09 compound treatment -0.0079 0.229 0.85 -0.0097 0.226 0.84 1.1914 1.0 SpOx1.1_008061 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O10 compound treatment -0.0119 0.225 0.83 -0.0147 0.221 0.82 1.1678 1.0 SpOx1.1_008062 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O11 compound treatment 1.0E-4 0.237 0.88 3.0E-4 0.236 0.87 1.2385 1.0 SpOx1.1_008063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O12 compound treatment -9.0E-4 0.236 0.87 0.0013 0.237 0.88 1.2385 1.0 SpOx1.1_008064 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O13 compound treatment -0.0059 0.231 0.85 -0.0067 0.229 0.85 1.2045 1.0 SpOx1.1_008065 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O14 compound treatment 0.0031 0.24 0.89 0.0023 0.238 0.88 1.2516 1.0 SpOx1.1_008066 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O15 compound treatment 0.0181 0.255 0.94 0.0193 0.255 0.94 1.3354 1.0 SpOx1.1_008067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O16 compound treatment -0.0069 0.23 0.85 -0.0027 0.233 0.86 1.2124 1.0 SpOx1.1_008068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O17 compound treatment 0.0051 0.242 0.9 0.0063 0.242 0.9 1.2673 1.0 SpOx1.1_008069 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O18 compound treatment -9.0E-4 0.236 0.87 0.0033 0.239 0.89 1.2438 1.0 SpOx1.1_008070 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O19 compound treatment -0.0059 0.231 0.85 -7.0E-4 0.235 0.87 1.2202 1.0 SpOx1.1_008071 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O20 compound treatment 0.0061 0.243 0.9 0.0033 0.239 0.89 1.2621 1.0 SpOx1.1_008072 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O21 compound treatment 0.0131 0.25 0.93 0.0123 0.248 0.92 1.3039 1.0 SpOx1.1_008073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O22 compound treatment 0.0151 0.252 0.93 0.0113 0.247 0.92 1.3066 1.0 SpOx1.1_008074 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O23 mock treatment 0.0211 0.258 0.95 0.0233 0.259 0.96 1.3537 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 O24 mock treatment -0.4678 -0.231 -0.85 -0.4656 -0.23 -0.85 -1.2056 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P01 compound treatment -0.0299 0.207 0.77 -0.0287 0.207 0.77 1.0841 1.0 SpOx1.1_008075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P02 compound treatment -0.0089 0.228 0.84 -0.0137 0.222 0.82 1.1783 0.9999 SpOx1.1_008076 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P03 compound treatment -0.0239 0.213 0.79 -0.0247 0.211 0.78 1.1103 1.0 SpOx1.1_008077 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P04 compound treatment -0.0149 0.222 0.82 -0.0157 0.22 0.82 1.1574 1.0 SpOx1.1_008078 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P05 compound treatment -0.0199 0.217 0.8 -0.0167 0.219 0.81 1.1417 1.0 SpOx1.1_008079 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P06 compound treatment -0.0119 0.225 0.83 -0.0117 0.224 0.83 1.1757 1.0 SpOx1.1_008080 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P07 compound treatment -0.0379 0.199 0.74 -0.0347 0.201 0.74 1.0474 1.0 SpOx1.1_008081 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P08 compound treatment -0.0329 0.204 0.75 -0.0187 0.217 0.8 1.1025 0.9995 SpOx1.1_008082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P09 compound treatment -0.0209 0.216 0.8 -0.0197 0.216 0.8 1.1312 1.0 SpOx1.1_008083 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P10 compound treatment -0.0269 0.21 0.78 -0.0227 0.213 0.79 1.1076 1.0 SpOx1.1_008084 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P11 compound treatment -0.0379 0.199 0.74 -0.0327 0.203 0.75 1.0527 0.9999 SpOx1.1_008085 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P12 compound treatment -0.0179 0.219 0.81 -0.0107 0.225 0.83 1.1626 0.9999 SpOx1.1_008086 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P13 compound treatment -0.0119 0.225 0.83 -0.0107 0.225 0.83 1.1782 1.0 SpOx1.1_008087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P14 compound treatment -0.0059 0.231 0.85 -0.0057 0.23 0.85 1.2071 1.0 SpOx1.1_008088 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P15 compound treatment -0.0279 0.209 0.77 -0.0247 0.211 0.78 1.0998 1.0 SpOx1.1_008089 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P16 compound treatment -0.0149 0.222 0.82 -0.0137 0.222 0.82 1.1626 1.0 SpOx1.1_008090 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P17 compound treatment -0.0079 0.229 0.85 -0.0117 0.224 0.83 1.1862 0.9999 SpOx1.1_008091 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P18 compound treatment -0.0289 0.208 0.77 -0.0297 0.206 0.76 1.0841 1.0 SpOx1.1_008092 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P19 compound treatment -0.0109 0.226 0.84 -0.0127 0.223 0.83 1.1757 1.0 SpOx1.1_008093 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P20 compound treatment -0.0069 0.23 0.85 -0.0097 0.226 0.84 1.194 1.0 SpOx1.1_008094 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P21 compound treatment -0.0119 0.225 0.83 -0.0117 0.224 0.83 1.1757 1.0 SpOx1.1_008095 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P22 compound treatment -0.0159 0.221 0.82 -0.0167 0.219 0.81 1.1521 1.0 SpOx1.1_008096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P23 mock treatment 0.0051 0.242 0.9 0.0063 0.242 0.9 1.2673 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1302 P24 mock treatment -0.4678 -0.231 -0.85 -0.4666 -0.231 -0.86 -1.2082 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A01 compound treatment -0.149 -0.144 -0.53 -0.1425 -0.138 -0.51 -0.7381 -0.9998 2020352 DHPC4_000001 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(F)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A02 compound treatment -0.087 -0.0817 -0.3 -0.0735 -0.0694 -0.26 -0.3953 -0.9968 2023548 DHPC4_000002 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A03 compound treatment -0.2 -0.195 -0.72 -0.2047 -0.201 -0.74 -1.0344 -0.9999 2023549 DHPC4_000003 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(F)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A04 compound treatment -0.089 -0.0837 -0.31 -0.0947 -0.0905 -0.34 -0.456 -0.9992 2021793 DHPC4_000004 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A05 compound treatment -0.131 -0.126 -0.46 -0.1405 -0.136 -0.51 -0.6858 -0.9991 2020460 DHPC4_000005 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(F)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A06 compound treatment -0.12 -0.115 -0.42 -0.1307 -0.127 -0.47 -0.6314 -0.9988 2021415 DHPC4_000006 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A07 compound treatment -0.09 -0.0847 -0.31 -0.1327 -0.129 -0.48 -0.5582 -0.9793 2021702 DHPC4_000007 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A08 compound treatment -0.093 -0.0877 -0.32 -0.0885 -0.0844 -0.31 -0.4503 -0.9998 2023550 DHPC4_000008 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A09 compound treatment -0.12 -0.115 -0.42 -0.0955 -0.0913 -0.34 -0.5392 -0.9937 2023551 DHPC4_000009 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A10 compound treatment -0.096 -0.0907 -0.34 -0.0875 -0.0834 -0.31 -0.4556 -0.9992 2021523 DHPC4_000010 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A11 mock treatment -0.066 -0.0607 -0.22 -0.0685 -0.0643 -0.24 -0.3272 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A12 mock treatment -0.068 -0.0627 -0.23 -0.0595 -0.0553 -0.2 -0.3089 -0.9981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A13 mock treatment -0.073 -0.0677 -0.25 -0.0755 -0.0713 -0.26 -0.3639 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A14 mock treatment -0.086 -0.0807 -0.3 -0.0725 -0.0683 -0.25 -0.39 -0.9966 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A15 mock treatment -0.068 -0.0627 -0.23 -0.0705 -0.0663 -0.25 -0.3377 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A16 mock treatment -0.08 -0.0747 -0.28 -0.0695 -0.0653 -0.24 -0.3664 -0.9978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A17 mock treatment -0.073 -0.0677 -0.25 -0.0757 -0.0715 -0.26 -0.3644 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A18 mock treatment -0.071 -0.0657 -0.24 -0.0645 -0.0603 -0.22 -0.3298 -0.9991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A19 mock treatment -0.075 -0.0697 -0.26 -0.0715 -0.0673 -0.25 -0.3586 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A20 mock treatment -0.071 -0.0657 -0.24 -0.0737 -0.0695 -0.26 -0.3539 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A21 mock treatment -0.082 -0.0767 -0.28 -0.0615 -0.0573 -0.21 -0.3507 -0.9898 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A22 mock treatment -0.077 -0.0717 -0.27 -0.0745 -0.0703 -0.26 -0.3717 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A23 mock treatment -0.454 -0.449 -1.66 -0.4548 -0.451 -1.67 -2.3538 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 A24 mock treatment -0.457 -0.452 -1.67 -0.4548 -0.451 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B01 compound treatment -0.063 -0.0577 -0.21 -0.0525 -0.0483 -0.18 -0.2775 -0.9962 2023552 DHPC4_000011 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B02 compound treatment -0.039 -0.0337 -0.12 -0.0495 -0.0453 -0.17 -0.2068 -0.9893 2023553 DHPC4_000012 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B03 compound treatment -0.044 -0.0387 -0.14 -0.0475 -0.0433 -0.16 -0.2147 -0.9984 2020339 DHPC4_000013 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCC(CC2)N3CCCCC3)c4ccccc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B04 compound treatment -0.021 -0.0157 -0.06 -0.0465 -0.0423 -0.16 -0.1519 -0.9087 2023554 DHPC4_000014 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B05 compound treatment -0.05 -0.0447 -0.17 -0.0635 -0.0593 -0.22 -0.2723 -0.9901 2023555 DHPC4_000015 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCC(CC2)N3CCCCC3)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B06 compound treatment -0.038 -0.0327 -0.12 -0.0415 -0.0373 -0.14 -0.1833 -0.9978 2023556 DHPC4_000016 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B07 compound treatment -0.109 -0.104 -0.38 -0.1148 -0.111 -0.41 -0.561 -0.9994 2020447 DHPC4_000017 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCC(CC2)N3CCCCC3)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B08 compound treatment -0.058 -0.0527 -0.19 -0.0605 -0.0563 -0.21 -0.2853 -0.9994 2023557 DHPC4_000018 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B09 compound treatment -0.065 -0.0597 -0.22 -0.0575 -0.0533 -0.2 -0.2958 -0.9985 2021689 DHPC4_000019 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B10 compound treatment -0.043 -0.0377 -0.14 -0.0565 -0.0523 -0.19 -0.2356 -0.987 2023558 DHPC4_000020 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B11 mock treatment 0.001 0.00629 0.02 0.0015 0.00566 0.02 0.0313 0.9987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B12 mock treatment -0.002 0.00328 0.01 0.0025 0.00666 0.02 0.026 0.9466 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B13 mock treatment 0.001 0.00629 0.02 0.0095 0.0137 0.05 0.0522 0.9377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B14 mock treatment 0.014 0.0193 0.07 -0.0025 0.00166 0.01 0.0548 0.7651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B15 mock treatment 0.005 0.0103 0.04 -0.0055 -0.00135 -0.01 0.0234 0.6087 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B16 mock treatment 0.004 0.00929 0.03 -0.0025 0.00166 0.01 0.0286 0.8205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B17 mock treatment 0.013 0.0183 0.07 0.0045 0.00866 0.03 0.0705 0.9419 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B18 mock treatment 0.013 0.0183 0.07 0.0045 0.00866 0.03 0.0705 0.9419 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B19 mock treatment 0.008 0.0133 0.05 0.0085 0.0127 0.05 0.0679 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B20 mock treatment 0.005 0.0103 0.04 0.0065 0.0107 0.04 0.0548 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B21 mock treatment 0.009 0.0143 0.05 0.0195 0.0236 0.09 0.0993 0.9707 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B22 mock treatment 0.003 0.00828 0.03 5.0E-4 0.00466 0.02 0.0339 0.9633 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B23 mock treatment -0.454 -0.449 -1.66 -0.4558 -0.452 -1.67 -2.3565 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 B24 mock treatment -0.456 -0.451 -1.67 -0.4558 -0.452 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C01 compound treatment -0.043 -0.0377 -0.14 -0.0485 -0.0443 -0.16 -0.2147 -0.9967 2021810 DHPC4_000021 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C02 compound treatment -0.057 -0.0517 -0.19 -0.0715 -0.0673 -0.25 -0.3116 -0.9914 2023559 DHPC4_000022 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Br)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C03 compound treatment -0.082 -0.0767 -0.28 -0.0805 -0.0763 -0.28 -0.4005 -1.0 2021432 DHPC4_000023 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C04 compound treatment -0.084 -0.0787 -0.29 -0.1005 -0.0963 -0.36 -0.4582 -0.9949 2023560 DHPC4_000024 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Br)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C05 compound treatment -0.03 -0.0247 -0.09 -0.0595 -0.0553 -0.2 -0.2095 -0.9338 2023561 DHPC4_000025 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C06 compound treatment -0.062 -0.0567 -0.21 -0.0515 -0.0473 -0.18 -0.2722 -0.996 2023562 DHPC4_000026 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Br)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C07 compound treatment -0.089 -0.0837 -0.31 -0.0745 -0.0703 -0.26 -0.4031 -0.9963 2021540 DHPC4_000027 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C08 compound treatment -0.01 -0.00471 -0.02 -0.0165 -0.0123 -0.05 -0.0446 -0.913 2023563 DHPC4_000028 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C09 compound treatment -0.113 -0.108 -0.4 -0.1065 -0.102 -0.38 -0.5497 -0.9997 2023564 DHPC4_000029 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2cccc(F)c2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C10 compound treatment -0.03 -0.0247 -0.09 -0.0245 -0.0203 -0.08 -0.1178 -0.9954 2023565 DHPC4_000030 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C11 mock treatment -0.006 -7.03E-4 0.0 -0.0025 0.00165 0.01 0.0025 0.3734 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C12 mock treatment -0.005 2.82E-4 0.0 -5.0E-4 0.00366 0.01 0.0103 0.7593 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C13 mock treatment -0.011 -0.0057 -0.02 5.0E-4 0.00466 0.02 -0.0027 -0.0994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C14 mock treatment -0.019 -0.0137 -0.05 0.0015 0.00566 0.02 -0.021 -0.3832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C15 mock treatment -0.015 -0.0097 -0.04 -0.0035 6.57E-4 0.0 -0.0236 -0.6576 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C16 mock treatment -0.001 0.00428 0.02 0.0035 0.00766 0.03 0.0313 0.962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C17 mock treatment 0.004 0.00928 0.03 0.0065 0.0107 0.04 0.0522 0.9975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C18 mock treatment 0.0 0.00528 0.02 5.0E-4 0.00466 0.02 0.026 0.9981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C19 mock treatment -0.003 0.00229 0.01 0.0035 0.00766 0.03 0.026 0.8796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C20 mock treatment -0.011 -0.0057 -0.02 -0.0035 6.57E-4 0.0 -0.0132 -0.6213 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C21 mock treatment -0.009 -0.0037 -0.01 0.0085 0.0127 0.05 0.0235 0.4806 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C22 mock treatment -0.003 0.00229 0.01 -0.0045 -3.43E-4 0.0 0.0051 0.5942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C23 mock treatment -0.457 -0.452 -1.67 -0.4548 -0.451 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 C24 mock treatment -0.456 -0.451 -1.67 -0.4548 -0.451 -1.67 -2.3591 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D01 compound treatment -0.071 -0.0657 -0.24 -0.0785 -0.0743 -0.28 -0.3665 -0.9981 2023566 DHPC4_000031 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D02 compound treatment -0.041 -0.0357 -0.13 -0.0405 -0.0363 -0.13 -0.1885 -1.0 2023567 DHPC4_000032 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)N[C@@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D03 compound treatment -0.104 -0.0987 -0.36 -0.0975 -0.0933 -0.35 -0.5025 -0.9996 2021797 DHPC4_000033 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D04 compound treatment -0.073 -0.0677 -0.25 -0.0475 -0.0433 -0.16 -0.2905 -0.9769 2023568 DHPC4_000034 C[C@@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2ccccc2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D05 compound treatment -0.118 -0.113 -0.42 -0.1108 -0.107 -0.4 -0.574 -0.9996 2021419 DHPC4_000035 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D06 compound treatment -0.044 -0.0387 -0.14 -0.0495 -0.0453 -0.17 -0.2199 -0.9968 2023569 DHPC4_000036 C[C@@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2cccs2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D07 compound treatment -0.111 -0.106 -0.39 -0.1108 -0.107 -0.4 -0.5557 -1.0 2023570 DHPC4_000037 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D08 compound treatment -0.069 -0.0637 -0.24 -0.0605 -0.0563 -0.21 -0.3141 -0.9982 2023571 DHPC4_000038 C[C@@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2ccsc2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D09 compound treatment -0.066 -0.0607 -0.22 -0.0745 -0.0703 -0.26 -0.343 -0.9972 2021527 DHPC4_000039 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)N3CCC(CC3)N4CCCCC4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D10 compound treatment -0.063 -0.0577 -0.21 -0.0615 -0.0573 -0.21 -0.301 -1.0 2023572 DHPC4_000040 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D11 mock treatment 0.007 0.0123 0.05 0.0065 0.0107 0.04 0.06 0.9976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D12 mock treatment -0.012 -0.00671 -0.02 0.0035 0.00766 0.03 0.0025 0.067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D13 mock treatment -0.001 0.00429 0.02 -0.0025 0.00166 0.01 0.0156 0.9148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D14 mock treatment -0.009 -0.0037 -0.01 0.0165 0.0206 0.08 0.0444 0.5715 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D15 mock treatment -0.016 -0.0107 -0.04 -0.0135 -0.00935 -0.03 -0.0525 -0.9978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D16 mock treatment -0.001 0.00428 0.02 0.0065 0.0107 0.04 0.0391 0.9195 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D17 mock treatment -0.009 -0.00372 -0.01 0.0115 0.0156 0.06 0.0313 0.5249 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D18 mock treatment 0.0 0.00528 0.02 0.0055 0.00966 0.04 0.0391 0.9594 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D19 mock treatment -0.008 -0.0027 -0.01 5.0E-4 0.00466 0.02 0.0051 0.2575 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D20 mock treatment -0.001 0.00429 0.02 -0.0095 -0.00535 -0.02 -0.0028 -0.1109 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D21 mock treatment -0.016 -0.0107 -0.04 0.0055 0.00966 0.04 -0.0027 -0.0503 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D22 mock treatment 0.006 0.0113 0.04 -5.0E-4 0.00366 0.01 0.0391 0.891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D23 mock treatment -0.456 -0.451 -1.67 -0.4558 -0.452 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 D24 mock treatment -0.455 -0.45 -1.66 -0.4548 -0.451 -1.67 -2.3565 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E01 compound treatment -0.096 -0.0907 -0.34 -0.0968 -0.0926 -0.34 -0.4798 -0.9999 2023573 DHPC4_000041 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2cccc(F)c2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E02 compound treatment -0.005 2.87E-4 0.0 -0.0145 -0.0103 -0.04 -0.0262 -0.6872 2023574 DHPC4_000042 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E03 compound treatment -0.084 -0.0787 -0.29 -0.0865 -0.0823 -0.3 -0.4214 -0.9997 2023575 DHPC4_000043 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2cccc(F)c2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E04 compound treatment -0.045 -0.0397 -0.15 -0.0355 -0.0313 -0.12 -0.1859 -0.9932 2023576 DHPC4_000044 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E05 compound treatment -0.043 -0.0377 -0.14 -0.0505 -0.0463 -0.17 -0.2199 -0.9947 2023577 DHPC4_000045 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E06 compound treatment -0.01 -0.0047 -0.02 -0.0075 -0.00331 -0.01 -0.021 -0.9855 2023578 DHPC4_000046 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E07 compound treatment -0.031 -0.0257 -0.1 -0.0495 -0.0453 -0.17 -0.1859 -0.9637 2023579 DHPC4_000047 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E08 compound treatment -0.01 -0.0047 -0.02 -0.0165 -0.0123 -0.05 -0.0446 -0.9126 2023580 DHPC4_000048 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccc(Br)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E09 compound treatment -0.024 -0.0187 -0.07 -0.0245 -0.0203 -0.08 -0.1021 -0.9991 2023581 DHPC4_000049 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E10 compound treatment -0.071 -0.0657 -0.24 -0.0595 -0.0553 -0.2 -0.3167 -0.9964 2023582 DHPC4_000050 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(I)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E11 mock treatment -0.015 -0.0097 -0.04 0.0115 0.0157 0.06 0.0157 0.2295 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E12 mock treatment 0.009 0.0143 0.05 -5.0E-4 0.00366 0.01 0.047 0.8605 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E13 mock treatment 0.01 0.0153 0.06 0.0055 0.00966 0.04 0.0653 0.9756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E14 mock treatment -0.007 -0.0017 -0.01 0.0045 0.00866 0.03 0.0182 0.5577 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E15 mock treatment 0.022 0.0273 0.1 0.0075 0.0117 0.04 0.1019 0.9283 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E16 mock treatment 0.001 0.00629 0.02 0.0085 0.0126 0.05 0.0496 0.9477 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E17 mock treatment -0.01 -0.00471 -0.02 0.0185 0.0226 0.08 0.047 0.5487 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E18 mock treatment 0.011 0.0163 0.06 0.0145 0.0186 0.07 0.0915 0.9977 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E19 mock treatment 0.0 0.00529 0.02 0.0145 0.0186 0.07 0.0627 0.8729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E20 mock treatment 0.003 0.00828 0.03 0.0095 0.0136 0.05 0.0574 0.9711 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E21 mock treatment 0.009 0.0143 0.05 0.0155 0.0196 0.07 0.0888 0.9876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E22 mock treatment 0.012 0.0173 0.06 0.0095 0.0137 0.05 0.081 0.9933 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E23 mock treatment -0.456 -0.451 -1.67 -0.4558 -0.452 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 E24 mock treatment -0.457 -0.452 -1.67 -0.4558 -0.452 -1.67 -2.3643 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F01 compound treatment -0.119 -0.114 -0.42 -0.1308 -0.127 -0.47 -0.629 -0.9985 2023583 DHPC4_000051 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc3OCOc3c2)c4ccccc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F02 compound treatment -0.009 -0.00372 -0.01 -0.0225 -0.0184 -0.07 -0.0578 -0.8332 2023584 DHPC4_000052 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F03 compound treatment -0.16 -0.155 -0.57 -0.1618 -0.158 -0.58 -0.8175 -0.9999 2023585 DHPC4_000053 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc3OCOc3c2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F04 compound treatment -0.027 -0.0217 -0.08 -0.0185 -0.0143 -0.05 -0.0942 -0.9797 2023586 DHPC4_000054 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F05 compound treatment -0.11 -0.105 -0.39 -0.1388 -0.135 -0.5 -0.6264 -0.9922 2023587 DHPC4_000055 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc3OCOc3c2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F06 compound treatment -0.041 -0.0357 -0.13 -0.0415 -0.0373 -0.14 -0.1911 -0.9997 2023588 DHPC4_000056 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F07 compound treatment -0.189 -0.184 -0.68 -0.1948 -0.191 -0.71 -0.9797 -0.9998 2023589 DHPC4_000057 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F08 compound treatment -0.023 -0.0177 -0.07 -0.0225 -0.0183 -0.07 -0.0943 -0.9998 2023590 DHPC4_000058 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F09 compound treatment -0.129 -0.124 -0.46 -0.1068 -0.103 -0.38 -0.5923 -0.9958 2023591 DHPC4_000059 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F10 compound treatment -0.025 -0.0197 -0.07 -0.0305 -0.0263 -0.1 -0.1204 -0.9897 2023592 DHPC4_000060 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)N[C@H](C)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F11 mock treatment -0.007 -0.0017 -0.01 0.0015 0.00566 0.02 0.0104 0.4738 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F12 mock treatment 0.002 0.00729 0.03 -0.0085 -0.00435 -0.02 0.0076 0.2435 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F13 mock treatment 0.014 0.0193 0.07 0.0055 0.00966 0.04 0.0758 0.9491 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F14 mock treatment 0.003 0.00828 0.03 0.0185 0.0226 0.08 0.081 0.9067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F15 mock treatment -0.003 0.00229 0.01 0.0165 0.0206 0.08 0.0601 0.7805 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F16 mock treatment 0.015 0.0203 0.08 0.0195 0.0236 0.09 0.115 0.997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F17 mock treatment 0.002 0.00729 0.03 0.0135 0.0176 0.07 0.0653 0.9232 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F18 mock treatment 0.005 0.0103 0.04 0.0255 0.0296 0.11 0.1046 0.8995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F19 mock treatment 0.014 0.0193 0.07 0.0065 0.0107 0.04 0.0784 0.9611 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F20 mock treatment 0.01 0.0153 0.06 0.0075 0.0117 0.04 0.0705 0.9912 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F21 mock treatment 0.004 0.00929 0.03 0.0105 0.0146 0.05 0.0627 0.9756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F22 mock treatment 0.009 0.0143 0.05 0.0105 0.0146 0.05 0.0757 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F23 mock treatment -0.456 -0.451 -1.67 -0.4568 -0.453 -1.68 -2.3643 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 F24 mock treatment -0.456 -0.451 -1.67 -0.456 -0.452 -1.67 -2.3622 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G01 compound treatment -0.094 -0.0887 -0.33 -0.1168 -0.113 -0.42 -0.527 -0.9929 2023593 DHPC4_000061 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G02 compound treatment -0.086 -0.0807 -0.3 -0.0885 -0.0843 -0.31 -0.4319 -0.9997 2023594 DHPC4_000062 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(I)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G03 compound treatment -0.062 -0.0567 -0.21 -0.0545 -0.0503 -0.19 -0.2801 -0.9983 2023595 DHPC4_000063 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G04 compound treatment -0.061 -0.0557 -0.21 -0.0705 -0.0663 -0.25 -0.3194 -0.9962 2023596 DHPC4_000064 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(I)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G05 compound treatment -0.073 -0.0677 -0.25 -0.0675 -0.0633 -0.23 -0.3429 -0.9995 2023597 DHPC4_000065 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3cccc(F)c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G06 compound treatment -0.039 -0.0337 -0.12 -0.0355 -0.0313 -0.12 -0.1702 -0.9993 2023598 DHPC4_000066 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G07 compound treatment 0.011 0.0163 0.06 0.0055 0.00966 0.04 0.0679 0.9691 2023599 DHPC4_000067 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2F)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G08 compound treatment -0.026 -0.0207 -0.08 -0.0325 -0.0283 -0.1 -0.1283 -0.988 2023600 DHPC4_000068 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G09 compound treatment -0.1 -0.0947 -0.35 -0.0958 -0.0916 -0.34 -0.4877 -0.9999 2023601 DHPC4_000069 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G10 compound treatment -0.03 -0.0247 -0.09 -0.0175 -0.0133 -0.05 -0.0995 -0.9581 2023602 DHPC4_000070 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G11 mock treatment -0.005 2.97E-4 0.0 0.0045 0.00866 0.03 0.0235 0.7309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G12 mock treatment 0.003 0.00829 0.03 0.0055 0.00966 0.04 0.047 0.997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G13 mock treatment 0.001 0.00629 0.02 -0.0105 -0.00635 -0.02 -2.0E-4 -0.0063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G14 mock treatment -0.009 -0.0037 -0.01 -0.0105 -0.00634 -0.02 -0.0263 -0.967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G15 mock treatment -0.006 -7.13E-4 0.0 -0.0015 0.00266 0.01 0.0051 0.5002 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G16 mock treatment -0.01 -0.00471 -0.02 -0.0165 -0.0124 -0.05 -0.0447 -0.9125 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G17 mock treatment 0.002 0.00729 0.03 0.0015 0.00566 0.02 0.0339 0.9923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G18 mock treatment -0.001 0.00428 0.02 0.0015 0.00566 0.02 0.026 0.9904 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G19 mock treatment 0.0 0.00529 0.02 -0.0095 -0.00535 -0.02 -2.0E-4 -0.0073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G20 mock treatment -0.023 -0.0177 -0.07 -0.0025 0.00166 0.01 -0.0419 -0.638 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G21 mock treatment -0.007 -0.0017 -0.01 -0.0105 -0.00635 -0.02 -0.0211 -0.8658 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G22 mock treatment -0.012 -0.0067 -0.02 -0.0015 0.00266 0.01 -0.0106 -0.3961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G23 mock treatment -0.456 -0.451 -1.67 -0.4568 -0.453 -1.68 -2.3643 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 G24 mock treatment -0.456 -0.451 -1.67 -0.4558 -0.452 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H01 compound treatment -0.057 -0.0517 -0.19 -0.0655 -0.0613 -0.23 -0.2958 -0.9963 2023603 DHPC4_000071 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H02 mock treatment -0.015 -0.0097 -0.04 0.0085 0.0127 0.05 0.0078 0.132 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H03 compound treatment -0.143 -0.138 -0.51 -0.1528 -0.149 -0.55 -0.7495 -0.9992 2023604 DHPC4_000072 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H04 mock treatment -0.009 -0.00371 -0.01 -0.0065 -0.00235 -0.01 -0.0159 -0.9761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H05 compound treatment -0.105 -0.0997 -0.37 -0.0995 -0.0953 -0.35 -0.5104 -0.9998 2023605 DHPC4_000073 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H06 mock treatment -0.006 -7.13E-4 0.0 -0.0035 6.57E-4 0.0 -1.0E-4 -0.0398 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H07 compound treatment -0.12 -0.115 -0.42 -0.1068 -0.103 -0.38 -0.5688 -0.9985 2023606 DHPC4_000074 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H08 mock treatment -0.012 -0.0067 -0.02 -5.0E-4 0.00366 0.01 -0.0079 -0.2812 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H09 compound treatment -0.034 -0.0287 -0.11 -0.0375 -0.0333 -0.12 -0.1624 -0.9972 2023607 DHPC4_000075 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCc3ccccc3C2)c4ccccc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H10 mock treatment -0.001 0.00428 0.02 0.0165 0.0206 0.08 0.0653 0.8357 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H11 mock treatment -0.013 -0.0077 -0.03 -0.0055 -0.00135 -0.01 -0.0237 -0.819 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H12 mock treatment -0.009 -0.00371 -0.01 -0.0035 6.57E-4 0.0 -0.008 -0.5727 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H13 mock treatment -0.002 0.00328 0.01 -0.0145 -0.0104 -0.04 -0.0185 -0.4609 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H14 mock treatment 0.005 0.0103 0.04 0.0045 0.00866 0.03 0.0496 0.9964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H15 mock treatment -0.005 2.97E-4 0.0 -0.0035 6.57E-4 0.0 0.0025 0.9352 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H16 mock treatment -0.005 2.82E-4 0.0 -0.0065 -0.00234 -0.01 -0.0054 -0.6177 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H17 mock treatment 0.005 0.0103 0.04 -0.0055 -0.00134 0.0 0.0234 0.6096 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H18 mock treatment -0.009 -0.0037 -0.01 -0.0095 -0.00534 -0.02 -0.0237 -0.9838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H19 mock treatment -0.007 -0.00171 -0.01 -0.0055 -0.00134 0.0 -0.008 -0.9928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H20 mock treatment -0.007 -0.00172 -0.01 -0.0065 -0.00235 -0.01 -0.0107 -0.9879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H21 mock treatment -0.004 0.0013 0.0 -0.0055 -0.00135 -0.01 -2.0E-4 -0.0222 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H22 mock treatment -0.004 0.00129 0.0 5.0E-4 0.00466 0.02 0.0156 0.8696 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H23 mock treatment -0.457 -0.452 -1.67 -0.4578 -0.454 -1.68 -2.3696 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 H24 mock treatment -0.458 -0.453 -1.67 -0.4558 -0.452 -1.67 -2.3669 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I01 compound treatment -0.072 -0.0667 -0.25 -0.0845 -0.0803 -0.3 -0.3848 -0.9957 2023608 DHPC4_000076 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2F)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I02 compound treatment -0.039 -0.0337 -0.12 -0.0335 -0.0293 -0.11 -0.1649 -0.9976 2023609 DHPC4_000077 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I03 compound treatment -0.042 -0.0367 -0.14 -0.0555 -0.0513 -0.19 -0.2304 -0.9864 2023610 DHPC4_000078 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I04 compound treatment -0.044 -0.0387 -0.14 -0.0435 -0.0393 -0.15 -0.2042 -1.0 2023611 DHPC4_000079 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I05 compound treatment -0.068 -0.0627 -0.23 -0.0485 -0.0443 -0.16 -0.2801 -0.9857 2023612 DHPC4_000080 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I06 compound treatment -0.026 -0.0207 -0.08 -0.0195 -0.0153 -0.06 -0.0943 -0.9891 2023613 DHPC4_000081 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccc(I)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I07 compound treatment -0.097 -0.0917 -0.34 -0.0875 -0.0833 -0.31 -0.4581 -0.9989 2023614 DHPC4_000082 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I08 compound treatment -0.1 -0.0947 -0.35 -0.1035 -0.0993 -0.37 -0.5079 -0.9997 2023615 DHPC4_000083 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I09 compound treatment -0.107 -0.102 -0.38 -0.1238 -0.12 -0.44 -0.5793 -0.9967 2023616 DHPC4_000084 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I10 compound treatment -0.133 -0.128 -0.47 -0.1248 -0.121 -0.45 -0.6499 -0.9996 2023617 DHPC4_000085 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I11 mock treatment -0.011 -0.0057 -0.02 0.0035 0.00766 0.03 0.0052 0.146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I12 mock treatment -0.006 -7.13E-4 0.0 -0.0065 -0.00234 -0.01 -0.008 -0.8822 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I13 mock treatment 0.0 0.00529 0.02 -5.0E-4 0.00366 0.01 0.0234 0.984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I14 mock treatment -0.009 -0.00372 -0.01 -0.0035 6.57E-4 0.0 -0.008 -0.5729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I15 mock treatment -0.022 -0.0167 -0.06 -0.0075 -0.00335 -0.01 -0.0525 -0.8327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I16 mock treatment -0.017 -0.0117 -0.04 -0.0075 -0.00334 -0.01 -0.0394 -0.8744 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I17 mock treatment 0.005 0.0103 0.04 -0.0185 -0.0144 -0.05 -0.0107 -0.1638 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I18 mock treatment 0.013 0.0183 0.07 -0.0075 -0.00334 -0.01 0.0391 0.5682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I19 mock treatment -0.012 -0.0067 -0.02 0.0065 0.0107 0.04 0.0104 0.223 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I20 mock treatment -0.005 2.82E-4 0.0 -0.0045 -3.41E-4 0.0 -2.0E-4 -0.0947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I21 mock treatment 0.006 0.0113 0.04 -0.0085 -0.00435 -0.02 0.0181 0.4045 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I22 mock treatment -0.001 0.00428 0.02 0.0095 0.0137 0.05 0.047 0.886 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I23 mock treatment -0.457 -0.452 -1.67 -0.4568 -0.453 -1.68 -2.3669 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 I24 mock treatment -0.457 -0.452 -1.67 -0.4558 -0.452 -1.67 -2.3643 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J01 compound treatment -0.058 -0.0527 -0.19 -0.0775 -0.0733 -0.27 -0.3299 -0.9867 2023618 DHPC4_000086 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCc3ccccc3C2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J02 mock treatment 0.007 0.0123 0.05 -0.0075 -0.00335 -0.01 0.0233 0.4955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J03 compound treatment -0.106 -0.101 -0.37 -0.1215 -0.117 -0.43 -0.5707 -0.997 2023619 DHPC4_000087 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCc3ccccc3C2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J04 mock treatment 0.001 0.00629 0.02 -0.0045 -3.53E-4 0.0 0.0155 0.6663 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J05 compound treatment -0.205 -0.2 -0.74 -0.1928 -0.189 -0.7 -1.0163 -0.9996 2023620 DHPC4_000088 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J06 mock treatment -0.006 -7.13E-4 0.0 0.0055 0.00966 0.04 0.0234 0.6532 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J07 compound treatment -0.06 -0.0547 -0.2 -0.0695 -0.0653 -0.24 -0.3142 -0.996 2023621 DHPC4_000089 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J08 mock treatment -0.002 0.00329 0.01 -0.0085 -0.00435 -0.02 -0.0028 -0.1392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J09 compound treatment -0.088 -0.0827 -0.31 -0.0975 -0.0933 -0.35 -0.4607 -0.9981 2023622 DHPC4_000090 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J10 mock treatment -0.014 -0.00871 -0.03 -0.0055 -0.00134 0.0 -0.0263 -0.8068 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J11 mock treatment -0.008 -0.0027 -0.01 0.0035 0.00766 0.03 0.013 0.432 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J12 mock treatment -0.01 -0.0047 -0.02 -0.0025 0.00166 0.01 -0.0079 -0.4305 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J13 mock treatment -0.033 -0.0277 -0.1 -0.0135 -0.00935 -0.03 -0.0969 -0.8964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J14 mock treatment -0.014 -0.0087 -0.03 -0.0085 -0.00434 -0.02 -0.0341 -0.9486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J15 mock treatment -0.003 0.00228 0.01 -0.0135 -0.00935 -0.03 -0.0185 -0.5197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J16 mock treatment -0.014 -0.00871 -0.03 -0.0195 -0.0154 -0.06 -0.063 -0.9637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J17 mock treatment 0.001 0.00629 0.02 -0.0185 -0.0144 -0.05 -0.0212 -0.3647 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J18 mock treatment -0.006 -7.13E-4 0.0 -0.0015 0.00266 0.01 0.0051 0.5001 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J19 mock treatment 0.004 0.00928 0.03 -0.0015 0.00266 0.01 0.0312 0.8747 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J20 mock treatment 0.008 0.0133 0.05 -0.0015 0.00266 0.01 0.0417 0.8326 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J21 mock treatment 0.003 0.00828 0.03 0.0135 0.0176 0.07 0.0679 0.9402 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J22 mock treatment 0.0 0.00528 0.02 -0.0135 -0.00935 -0.03 -0.0107 -0.2689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J23 mock treatment -0.456 -0.451 -1.67 -0.4568 -0.453 -1.68 -2.3643 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 J24 mock treatment -0.458 -0.453 -1.67 -0.4568 -0.453 -1.68 -2.3696 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K01 compound treatment -0.044 -0.0387 -0.14 -0.0525 -0.0483 -0.18 -0.2278 -0.9939 2023623 DHPC4_000091 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K02 compound treatment -0.067 -0.0617 -0.23 -0.0765 -0.0723 -0.27 -0.3508 -0.9968 2023624 DHPC4_000092 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K03 compound treatment -0.043 -0.0377 -0.14 -0.0535 -0.0493 -0.18 -0.2278 -0.9911 2023625 DHPC4_000093 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccccc3F 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K04 compound treatment -0.04 -0.0347 -0.13 -0.0255 -0.0213 -0.08 -0.1466 -0.9727 2023626 DHPC4_000094 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K05 compound treatment -0.172 -0.167 -0.62 -0.1608 -0.157 -0.58 -0.8462 -0.9995 2023627 DHPC4_000095 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)OCc2ccc(F)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K06 compound treatment -0.022 -0.0167 -0.06 -0.0305 -0.0263 -0.1 -0.1126 -0.9758 2023628 DHPC4_000096 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K07 compound treatment -0.105 -0.0997 -0.37 -0.0635 -0.0593 -0.22 -0.4161 -0.9695 2023629 DHPC4_000097 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)OCc2ccc(F)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K08 compound treatment -0.054 -0.0487 -0.18 -0.0325 -0.0283 -0.1 -0.2015 -0.9669 2023630 DHPC4_000098 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K09 compound treatment -0.13 -0.125 -0.46 -0.1188 -0.115 -0.42 -0.6263 -0.9992 2023631 DHPC4_000099 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)OCc2ccc(F)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K10 compound treatment -0.048 -0.0427 -0.16 -0.0405 -0.0363 -0.13 -0.2068 -0.9968 2023632 DHPC4_000100 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K11 mock treatment -0.01 -0.0047 -0.02 -0.0025 0.00166 0.01 -0.008 -0.4313 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K12 mock treatment -0.004 0.00129 0.0 -0.0045 -3.43E-4 0.0 0.0025 0.5008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K13 mock treatment -0.03 -0.0247 -0.09 -0.0075 -0.00334 -0.01 -0.0733 -0.7957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K14 mock treatment 0.002 0.00729 0.03 -0.0045 -3.41E-4 0.0 0.0182 0.6732 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K15 mock treatment -0.001 0.00428 0.02 -0.0055 -0.00134 0.0 0.0077 0.4626 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K16 mock treatment 0.0 0.00529 0.02 0.0015 0.00566 0.02 0.0286 0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K17 mock treatment -0.018 -0.0127 -0.05 -0.0075 -0.00335 -0.01 -0.042 -0.8644 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K18 mock treatment 0.0 0.00529 0.02 -0.0195 -0.0154 -0.06 -0.0264 -0.4389 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K19 mock treatment -0.007 -0.00172 -0.01 -0.0155 -0.0114 -0.04 -0.0342 -0.8048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K20 mock treatment -0.019 -0.0137 -0.05 -0.0045 -3.41E-4 0.0 -0.0367 -0.7245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K21 mock treatment -0.006 -7.13E-4 0.0 -0.0125 -0.00835 -0.03 -0.0238 -0.7646 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K22 mock treatment 0.005 0.0103 0.04 0.0085 0.0127 0.05 0.0601 0.9946 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K23 mock treatment -0.456 -0.451 -1.67 -0.4558 -0.452 -1.67 -2.3617 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 K24 mock treatment -0.458 -0.453 -1.67 -0.4578 -0.454 -1.68 -2.3722 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L01 compound treatment -0.258 -0.253 -0.93 -0.2948 -0.291 -1.08 -1.4222 -0.9975 2023633 DHPC4_000101 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L02 mock treatment 0.007 0.0123 0.05 0.0155 0.0196 0.07 0.0836 0.9743 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L03 compound treatment -0.063 -0.0577 -0.21 -0.0525 -0.0483 -0.18 -0.2775 -0.9962 2023634 DHPC4_000102 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L04 mock treatment 0.01 0.0153 0.06 0.0025 0.00666 0.02 0.0575 0.9309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L05 compound treatment -0.092 -0.0867 -0.32 -0.0845 -0.0803 -0.3 -0.4371 -0.9993 2023635 DHPC4_000103 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)N3CCc4ccccc4C3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L06 mock treatment 0.014 0.0193 0.07 -5.0E-4 0.00366 0.01 0.06 0.8266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L07 compound treatment -0.197 -0.192 -0.71 -0.1978 -0.194 -0.72 -1.0085 -1.0 2023636 DHPC4_000104 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2ccc(F)cc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L08 mock treatment 0.002 0.00729 0.03 -0.0025 0.00166 0.01 0.0234 0.8466 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L09 compound treatment -0.149 -0.144 -0.53 -0.1478 -0.144 -0.53 -0.752 -1.0 2023637 DHPC4_000105 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2ccc(F)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L10 mock treatment -0.008 -0.00271 -0.01 0.0135 0.0176 0.07 0.0391 0.5917 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L11 mock treatment 0.002 0.00729 0.03 0.0115 0.0156 0.06 0.0601 0.9392 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L12 mock treatment 0.006 0.0113 0.04 0.0065 0.0106 0.04 0.0574 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L13 mock treatment 0.009 0.0143 0.05 -0.0235 -0.0193 -0.07 -0.0132 -0.1486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L14 mock treatment 0.005 0.0103 0.04 0.0075 0.0116 0.04 0.0574 0.998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L15 mock treatment 0.011 0.0163 0.06 -5.0E-4 0.00366 0.01 0.0522 0.8451 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L16 mock treatment 0.004 0.0093 0.03 0.0035 0.00765 0.03 0.0443 0.9954 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L17 mock treatment 0.012 0.0173 0.06 0.0195 0.0236 0.09 0.1072 0.988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L18 mock treatment 0.022 0.0273 0.1 0.0025 0.00665 0.02 0.0888 0.8546 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L19 mock treatment 0.007 0.0123 0.05 0.0055 0.00965 0.04 0.0574 0.9929 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L20 mock treatment 0.011 0.0163 0.06 0.0085 0.0126 0.05 0.0757 0.9923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L21 mock treatment 0.003 0.00828 0.03 0.0165 0.0206 0.08 0.0758 0.9192 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L22 mock treatment 0.018 0.0233 0.09 0.0215 0.0256 0.1 0.1281 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L23 mock treatment -0.458 -0.453 -1.67 -0.4558 -0.452 -1.67 -2.3669 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 L24 mock treatment -0.457 -0.452 -1.67 -0.457 -0.453 -1.68 -2.3675 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M01 compound treatment -0.023 -0.0177 -0.07 -0.0415 -0.0373 -0.14 -0.1441 -0.9417 2023638 DHPC4_000106 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M02 compound treatment -0.004 0.0013 0.0 -0.0225 -0.0183 -0.07 -0.0446 -0.6555 2023639 DHPC4_000107 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M03 compound treatment -0.01 -0.0047 -0.02 -0.0125 -0.00831 -0.03 -0.0341 -0.9634 2023640 DHPC4_000108 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M04 compound treatment -0.021 -0.0157 -0.06 -0.0215 -0.0173 -0.06 -0.0864 -0.9988 2023641 DHPC4_000109 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCc3ccc(Cl)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M05 compound treatment -0.008 -0.0027 -0.01 -0.0155 -0.0113 -0.04 -0.0367 -0.8518 2023642 DHPC4_000110 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M06 compound treatment -0.012 -0.0067 -0.02 -0.0055 -0.00131 0.0 -0.021 -0.83 2023643 DHPC4_000111 CN(Cc1ccc(F)cc1)C(=O)C2=C[C@H](C[C@@H](OCCCCO)O2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M07 compound treatment -0.094 -0.0887 -0.33 -0.0795 -0.0753 -0.28 -0.4293 -0.9968 2023644 DHPC4_000112 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M08 compound treatment -0.028 -0.0227 -0.08 -0.0225 -0.0183 -0.07 -0.1073 -0.9944 2023645 DHPC4_000113 CN(Cc1ccc(F)cc1)C(=O)C2=C[C@H](C[C@@H](OCCCCO)O2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M09 compound treatment -0.065 -0.0597 -0.22 -0.0525 -0.0483 -0.18 -0.2827 -0.9946 2023646 DHPC4_000114 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M10 compound treatment -0.06 -0.0547 -0.2 -0.0585 -0.0543 -0.2 -0.2853 -1.0 2023647 DHPC4_000115 CN(Cc1ccc(F)cc1)C(=O)C2=C[C@H](C[C@@H](OCCCCO)O2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M11 mock treatment 0.006 0.0113 0.04 -0.0045 -3.41E-4 0.0 0.0286 0.6854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M12 mock treatment 0.006 0.0113 0.04 -0.0065 -0.00234 -0.01 0.0234 0.5483 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M13 mock treatment -0.003 0.00229 0.01 0.0015 0.00566 0.02 0.0208 0.9202 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M14 mock treatment 0.008 0.0133 0.05 0.0105 0.0146 0.05 0.0731 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M15 mock treatment 0.001 0.00629 0.02 -0.0095 -0.00535 -0.02 0.0024 0.0789 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M16 mock treatment 0.004 0.00928 0.03 -0.0125 -0.00835 -0.03 0.0024 0.0516 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M17 mock treatment -0.001 0.00428 0.02 0.0095 0.0136 0.05 0.047 0.8861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M18 mock treatment 0.012 0.0173 0.06 0.0115 0.0156 0.06 0.0862 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M19 mock treatment 0.011 0.0163 0.06 0.0035 0.00766 0.03 0.0627 0.941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M20 mock treatment -0.001 0.00428 0.02 0.0035 0.00766 0.03 0.0313 0.962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M21 mock treatment 0.009 0.0143 0.05 0.0115 0.0156 0.06 0.0784 0.9989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M22 mock treatment 0.018 0.0233 0.09 0.0155 0.0196 0.07 0.1124 0.9965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M23 mock treatment -0.457 -0.452 -1.67 -0.4568 -0.453 -1.68 -2.3669 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 M24 mock treatment -0.458 -0.453 -1.67 -0.4578 -0.454 -1.68 -2.3722 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N01 compound treatment -0.106 -0.101 -0.37 -0.0945 -0.0903 -0.33 -0.4999 -0.9986 2023648 DHPC4_000116 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2ccc(F)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N02 mock treatment -0.009 -0.00371 -0.01 -0.0175 -0.0134 -0.05 -0.0447 -0.8705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N03 compound treatment -0.072 -0.0667 -0.25 -0.1015 -0.0973 -0.36 -0.4294 -0.9828 2023649 DHPC4_000117 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N04 mock treatment -0.005 2.87E-4 0.0 -0.0095 -0.00535 -0.02 -0.0133 -0.6683 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N05 compound treatment -0.033 -0.0277 -0.1 -0.0275 -0.0233 -0.09 -0.1335 -0.9964 2023650 DHPC4_000118 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N06 mock treatment -0.008 -0.00271 -0.01 -0.0015 0.00266 0.01 -1.0E-4 -0.0081 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N07 compound treatment -0.074 -0.0687 -0.25 -0.0615 -0.0573 -0.21 -0.3298 -0.996 2023651 DHPC4_000119 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N08 mock treatment -0.034 -0.0287 -0.11 0.0015 0.00566 0.02 -0.0602 -0.5566 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N09 compound treatment -0.114 -0.109 -0.4 -0.0995 -0.0953 -0.35 -0.534 -0.9979 2023652 DHPC4_000120 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N10 mock treatment 0.0 0.00529 0.02 5.0E-4 0.00466 0.02 0.026 0.9981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N11 mock treatment -0.013 -0.0077 -0.03 -0.0155 -0.0114 -0.04 -0.0499 -0.982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N12 mock treatment 0.002 0.00729 0.03 -0.0035 6.62E-4 0.0 0.0208 0.7683 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N13 mock treatment 0.005 0.0103 0.04 5.0E-4 0.00466 0.02 0.0391 0.9361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N14 mock treatment 0.011 0.0163 0.06 -0.0185 -0.0143 -0.05 0.0051 0.064 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N15 mock treatment -0.013 -0.0077 -0.03 0.0115 0.0156 0.06 0.0209 0.3229 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N16 mock treatment 0.005 0.0103 0.04 0.0015 0.00566 0.02 0.0417 0.9606 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N17 mock treatment -0.003 0.00229 0.01 -0.0125 -0.00835 -0.03 -0.0159 -0.4957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N18 mock treatment 0.006 0.0113 0.04 0.0045 0.00865 0.03 0.0522 0.9914 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N19 mock treatment -0.009 -0.00371 -0.01 -0.0015 0.00266 0.01 -0.0027 -0.1622 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N20 mock treatment -0.004 0.00129 0.0 0.0055 0.00965 0.04 0.0286 0.7942 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N21 mock treatment 0.016 0.0213 0.08 0.0095 0.0136 0.05 0.0914 0.9771 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N22 mock treatment 0.008 0.0133 0.05 0.0035 0.00766 0.03 0.0548 0.9659 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N23 mock treatment -0.458 -0.453 -1.67 -0.4568 -0.453 -1.68 -2.3696 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 N24 mock treatment -0.459 -0.454 -1.68 -0.4578 -0.454 -1.68 -2.3748 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O01 compound treatment -0.078 -0.0727 -0.27 -0.0525 -0.0483 -0.18 -0.3167 -0.9805 2023653 DHPC4_000121 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)OCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O02 compound treatment -0.003 0.0023 0.01 -0.0145 -0.0103 -0.04 -0.021 -0.5367 2023654 DHPC4_000122 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O03 compound treatment -0.059 -0.0537 -0.2 -0.0695 -0.0653 -0.24 -0.3115 -0.9952 2020335 DHPC4_000123 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2)c3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O04 compound treatment 0.0 0.0053 0.02 -0.0025 0.00166 0.01 0.0182 0.8863 2023655 DHPC4_000124 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2cccs2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O05 compound treatment -0.048 -0.0427 -0.16 -0.0505 -0.0463 -0.17 -0.233 -0.9991 2023656 DHPC4_000125 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O06 compound treatment -0.003 0.0023 0.01 -0.0065 -0.0023 -0.01 0.0 -0.0024 2023657 DHPC4_000126 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccsc2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O07 compound treatment -0.105 -0.0997 -0.37 -0.0958 -0.0916 -0.34 -0.5008 -0.9991 2020443 DHPC4_000127 OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ccccc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O08 compound treatment -0.029 -0.0237 -0.09 -0.0335 -0.0293 -0.11 -0.1388 -0.9944 2023658 DHPC4_000128 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccccc2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O09 compound treatment -0.058 -0.0527 -0.19 -0.0605 -0.0563 -0.21 -0.2853 -0.9994 2021685 DHPC4_000129 CCO[C@H]1OC(=C[C@H]([C@H]1CCOCCOCCO)c2ccccc2)C(=O)NCc3ccccc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O10 compound treatment -0.022 -0.0167 -0.06 -0.0215 -0.0173 -0.06 -0.089 -0.9998 2023659 DHPC4_000130 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)N(C)Cc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O11 mock treatment 0.003 0.00829 0.03 -0.0045 -3.43E-4 0.0 0.0208 0.6772 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O12 mock treatment 0.006 0.0113 0.04 -0.0115 -0.00735 -0.03 0.0103 0.206 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O13 mock treatment -0.001 0.00428 0.02 0.0055 0.00965 0.04 0.0365 0.9329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O14 mock treatment 0.007 0.0123 0.05 0.0045 0.00865 0.03 0.0548 0.9854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O15 mock treatment 0.021 0.0263 0.1 0.0035 0.00766 0.03 0.0888 0.8769 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O16 mock treatment 0.001 0.00629 0.02 0.0125 0.0166 0.06 0.0601 0.911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O17 mock treatment 0.001 0.00629 0.02 0.0105 0.0146 0.05 0.0548 0.9284 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O18 mock treatment 0.007 0.0123 0.05 -0.0105 -0.00634 -0.02 0.0155 0.3035 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O19 mock treatment 0.0 0.00529 0.02 0.0035 0.00766 0.03 0.0339 0.9835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O20 mock treatment 0.011 0.0163 0.06 0.0035 0.00765 0.03 0.0626 0.9408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O21 mock treatment 0.023 0.0283 0.1 0.0055 0.00966 0.04 0.0993 0.8979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O22 mock treatment 0.016 0.0213 0.08 0.0125 0.0166 0.06 0.0993 0.9927 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O23 mock treatment -0.458 -0.453 -1.67 -0.4568 -0.453 -1.68 -2.3696 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 O24 mock treatment -0.458 -0.453 -1.67 -0.4568 -0.453 -1.68 -2.3696 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P01 compound treatment -0.046 -0.0407 -0.15 -0.0525 -0.0483 -0.18 -0.233 -0.9963 2023660 DHPC4_000131 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2cccs2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P02 mock treatment -0.006 -7.13E-4 0.0 -0.0055 -0.00134 0.0 -0.0054 -0.9561 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P03 compound treatment -0.057 -0.0517 -0.19 -0.0395 -0.0353 -0.13 -0.2277 -0.9829 2023661 DHPC4_000132 CCO[C@H]1OC(=C[C@H]([C@H]1CCCO)c2ccsc2)C(=O)NCCc3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P04 mock treatment -0.009 -0.00372 -0.01 -0.0115 -0.00735 -0.03 -0.029 -0.9499 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P05 compound treatment -0.112 -0.107 -0.39 -0.1245 -0.12 -0.45 -0.5943 -0.9981 2023662 DHPC4_000133 C[C@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2ccccc2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P06 mock treatment -0.002 0.00329 0.01 -0.0195 -0.0154 -0.06 -0.0316 -0.5438 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P07 compound treatment -0.159 -0.154 -0.57 -0.1508 -0.147 -0.54 -0.786 -0.9997 2023663 DHPC4_000134 C[C@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2cccs2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P08 mock treatment -0.016 -0.0107 -0.04 -0.0095 -0.00534 -0.02 -0.042 -0.9486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P09 compound treatment -0.096 -0.0907 -0.34 -0.1065 -0.102 -0.38 -0.5053 -0.9981 2023664 DHPC4_000135 C[C@H](NC(=O)C1=C[C@H](C[C@@H](OCCCCO)O1)c2ccsc2)c3ccc(F)cc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P10 mock treatment -0.017 -0.0117 -0.04 -0.0235 -0.0194 -0.07 -0.0813 -0.9708 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P11 mock treatment -0.027 -0.0217 -0.08 -0.0355 -0.0314 -0.12 -0.1389 -0.9837 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P12 mock treatment -0.012 -0.00671 -0.02 -0.0195 -0.0154 -0.06 -0.0578 -0.9309 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P13 mock treatment -0.01 -0.00471 -0.02 -0.0275 -0.0234 -0.09 -0.0735 -0.8328 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P14 mock treatment -0.002 0.00329 0.01 -0.0125 -0.00834 -0.03 -0.0133 -0.3994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P15 mock treatment -0.011 -0.00571 -0.02 -0.0095 -0.00534 -0.02 -0.0289 -0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P16 mock treatment -0.004 0.00129 0.0 -0.0165 -0.0123 -0.05 -0.029 -0.6301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P17 mock treatment -0.001 0.00429 0.02 -0.0245 -0.0204 -0.08 -0.0421 -0.5465 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P18 mock treatment -0.021 -0.0157 -0.06 -0.0035 6.97E-4 0.0 -0.0392 -0.675 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P19 mock treatment -0.007 -0.00171 -0.01 -0.0045 -3.43E-4 0.0 -0.0054 -0.8323 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P20 mock treatment -0.004 0.00129 0.0 -0.0035 6.97E-4 0.0 0.0052 0.9588 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P21 mock treatment -0.005 2.87E-4 0.0 0.0065 0.0107 0.04 0.0288 0.7258 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P22 mock treatment -0.009 -0.00371 -0.01 5.0E-4 0.00466 0.02 0.0025 0.1131 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P23 mock treatment -0.459 -0.454 -1.68 -0.4588 -0.455 -1.68 -2.3774 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1317 P24 mock treatment -0.459 -0.454 -1.68 -0.4578 -0.454 -1.68 -2.3748 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A01 compound treatment -0.0844 -0.0784 -0.29 -0.1055 -0.1 -0.37 -0.4673 -0.9926 2023665 DHPC5_000001 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)Nc3cccc(O)c3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A02 compound treatment -0.0843 -0.0784 -0.29 -0.1055 -0.1 -0.37 -0.4673 -0.9925 2023666 DHPC5_000002 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)Nc3cccc(O)c3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A03 compound treatment -0.1255 -0.12 -0.44 -0.1175 -0.112 -0.42 -0.6062 -0.9995 2023667 DHPC5_000003 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)Nc3ccc(O)cc3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A04 compound treatment -0.1305 -0.125 -0.46 -0.1212 -0.116 -0.43 -0.629 -0.9994 2023668 DHPC5_000004 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A05 compound treatment -0.0734 -0.0674 -0.25 -0.0795 -0.0741 -0.27 -0.3705 -0.9988 2023669 DHPC5_000005 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)NCc3ncc[nH]3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A06 compound treatment -0.1045 -0.0985 -0.36 -0.1015 -0.0961 -0.36 -0.5093 -0.9999 2023670 DHPC5_000006 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)NCc3ncc[nH]3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A07 compound treatment -0.1155 -0.109 -0.4 -0.1215 -0.116 -0.43 -0.5905 -0.9995 2023671 DHPC5_000007 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)NC3(CC4CC5CC(C4)C3)C5)c(=O)n(c6ccccc6)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A08 compound treatment -0.1084 -0.102 -0.38 -0.1105 -0.105 -0.39 -0.5432 -0.9999 2023672 DHPC5_000008 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)NC3(CC4CC5CC(C4)C3)C5)c(=O)n(c6ccccc6)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A09 compound treatment -0.0794 -0.0734 -0.27 -0.1082 -0.103 -0.38 -0.4613 -0.9861 2023673 DHPC5_000009 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)NCCc3c[nH]cn3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A10 compound treatment -0.0984 -0.0924 -0.34 -0.1125 -0.107 -0.4 -0.5223 -0.9972 2023674 DHPC5_000010 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)NCCc3c[nH]cn3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A11 mock treatment -0.0704 -0.0644 -0.24 -0.0675 -0.0621 -0.23 -0.3312 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A12 mock treatment -0.0654 -0.0594 -0.22 -0.0645 -0.0591 -0.22 -0.3102 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A13 mock treatment -0.0854 -0.0794 -0.29 -0.0795 -0.0741 -0.27 -0.4018 -0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A14 mock treatment -0.0804 -0.0744 -0.28 -0.0832 -0.0778 -0.29 -0.3985 -0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A15 mock treatment -0.0784 -0.0724 -0.27 -0.0705 -0.0651 -0.24 -0.36 -0.9987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A16 mock treatment -0.0684 -0.0624 -0.23 -0.0815 -0.0761 -0.28 -0.3626 -0.995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A17 mock treatment -0.0765 -0.0705 -0.26 -0.0735 -0.0681 -0.25 -0.3628 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A18 mock treatment -0.0704 -0.0644 -0.24 -0.0755 -0.0701 -0.26 -0.3522 -0.9991 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A19 mock treatment -0.0734 -0.0674 -0.25 -0.0782 -0.0728 -0.27 -0.3671 -0.9992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A20 mock treatment -0.0805 -0.0745 -0.28 -0.0765 -0.0711 -0.26 -0.3812 -0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A21 mock treatment -0.0694 -0.0634 -0.23 -0.0922 -0.0868 -0.32 -0.3933 -0.9879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A22 mock treatment -0.0785 -0.0725 -0.27 -0.0892 -0.0838 -0.31 -0.4092 -0.9973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A23 mock treatment -0.4499 -0.444 -1.64 -0.4533 -0.448 -1.66 -2.3342 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 A24 mock treatment -0.4489 -0.443 -1.64 -0.4543 -0.449 -1.66 -2.3343 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B01 compound treatment -0.0174 -0.0114 -0.04 -0.0245 -0.0191 -0.07 -0.0799 -0.9688 2023675 DHPC5_000011 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)Nc3cccc(O)c3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B02 compound treatment -0.0294 -0.0234 -0.09 -0.0315 -0.0261 -0.1 -0.1296 -0.9984 2023676 DHPC5_000012 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)Nc3cccc(O)c3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B03 compound treatment -0.0304 -0.0244 -0.09 -0.0225 -0.0171 -0.06 -0.1087 -0.9851 2023677 DHPC5_000013 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)Nc3ccc(O)cc3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B04 compound treatment -0.0674 -0.0614 -0.23 -0.0575 -0.0521 -0.19 -0.2971 -0.9968 2023678 DHPC5_000014 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B05 compound treatment -0.0414 -0.0354 -0.13 -0.0335 -0.0281 -0.1 -0.1662 -0.9937 2023679 DHPC5_000015 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)NCc3ncc[nH]3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B06 compound treatment -0.0374 -0.0314 -0.12 -0.0445 -0.0391 -0.14 -0.1845 -0.9939 2023680 DHPC5_000016 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)NCc3ncc[nH]3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B07 compound treatment -0.0614 -0.0554 -0.2 -0.0525 -0.0471 -0.17 -0.2684 -0.9969 2023681 DHPC5_000017 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)NC3(CC4CC5CC(C4)C3)C5)c(=O)n(c6ccccc6)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B08 compound treatment -0.0364 -0.0304 -0.11 -0.0355 -0.0301 -0.11 -0.1584 -1.0 2023682 DHPC5_000018 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)NC3(CC4CC5CC(C4)C3)C5)c(=O)n(c6ccccc6)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B09 compound treatment -0.0414 -0.0354 -0.13 -0.0565 -0.0511 -0.19 -0.2265 -0.9836 2023683 DHPC5_000019 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)NCCc3c[nH]cn3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B10 compound treatment -0.0454 -0.0394 -0.15 -0.0465 -0.0411 -0.15 -0.2109 -0.9997 2023684 DHPC5_000020 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)NCCc3c[nH]cn3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B11 mock treatment -3.0E-4 0.00568 0.02 5.0E-4 0.00583 0.02 0.0301 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B12 mock treatment 7.0E-4 0.00668 0.02 -0.0056 -1.69E-4 0.0 0.017 0.689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B13 mock treatment 0.0056 0.0116 0.04 4.0E-4 0.00583 0.02 0.0457 0.9492 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B14 mock treatment -0.0053 6.77E-4 0.0 0.0104 0.0158 0.06 0.0432 0.7366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B15 mock treatment -0.0053 6.37E-4 0.0 0.0014 0.00683 0.03 0.0196 0.7696 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B16 mock treatment -3.0E-4 0.00568 0.02 0.0014 0.00683 0.03 0.0327 0.9957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B17 mock treatment -3.0E-4 0.00568 0.02 0.0115 0.0169 0.06 0.059 0.8955 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B18 mock treatment -3.0E-4 0.00568 0.02 0.0075 0.0128 0.05 0.0485 0.9325 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B19 mock treatment 7.0E-4 0.00668 0.02 -6.0E-4 0.00483 0.02 0.0301 0.9875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B20 mock treatment 0.0057 0.0117 0.04 0.0035 0.00883 0.03 0.0537 0.9907 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B21 mock treatment 0.0127 0.0186 0.07 -5.0E-4 0.00483 0.02 0.0614 0.8622 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B22 mock treatment -0.0033 0.00267 0.01 -0.0076 -0.00217 -0.01 0.0013 0.1027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B23 mock treatment -0.4489 -0.443 -1.64 -0.4493 -0.444 -1.64 -2.3212 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 B24 mock treatment -0.4499 -0.444 -1.64 -0.4543 -0.449 -1.66 -2.3369 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C01 compound treatment -0.0314 -0.0254 -0.09 -0.0375 -0.0321 -0.12 -0.1507 -0.9931 2023685 DHPC5_000021 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C02 compound treatment -0.0323 -0.0264 -0.1 -0.0165 -0.0111 -0.04 -0.0981 -0.9268 2023686 DHPC5_000022 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C03 compound treatment -0.0223 -0.0164 -0.06 -0.0215 -0.0161 -0.06 -0.085 -1.0 2023687 DHPC5_000023 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C04 compound treatment -0.0444 -0.0384 -0.14 -0.0245 -0.0191 -0.07 -0.1506 -0.9486 2023688 DHPC5_000024 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C05 compound treatment -0.0284 -0.0224 -0.08 0.0084 0.0138 0.05 -0.0222 -0.2285 2023689 DHPC5_000025 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C06 compound treatment -0.0053 6.37E-4 0.0 -0.0075 -0.00212 -0.01 -0.0039 -0.4741 2023690 DHPC5_000026 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C07 compound treatment -0.0143 -0.00832 -0.03 -0.0215 -0.0161 -0.06 -0.064 -0.9523 2023691 DHPC5_000027 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccc6OCOc6c5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C08 compound treatment -0.0594 -0.0534 -0.2 -0.0315 -0.0261 -0.1 -0.2081 -0.9464 2023692 DHPC5_000028 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccc6OCOc6c5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C09 compound treatment -0.0114 -0.00536 -0.02 -0.0095 -0.00414 -0.02 -0.0249 -0.9919 2023693 DHPC5_000029 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C10 compound treatment -0.0053 6.77E-4 0.0 -0.0155 -0.0101 -0.04 -0.0248 -0.6585 2023694 DHPC5_000030 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C11 mock treatment -0.0104 -0.00436 -0.02 -0.0125 -0.00714 -0.03 -0.0301 -0.9719 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C12 mock treatment -0.0043 0.00167 0.01 -0.0066 -0.00117 0.0 0.0013 0.174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C13 mock treatment -0.0043 0.00168 0.01 -0.0145 -0.00914 -0.03 -0.0196 -0.5682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C14 mock treatment -0.0013 0.00468 0.02 -0.0115 -0.00612 -0.02 -0.0038 -0.1334 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C15 mock treatment -0.0073 -0.00132 0.0 -0.0165 -0.0111 -0.04 -0.0326 -0.7854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C16 mock treatment -0.0033 0.00268 0.01 -0.0035 0.00183 0.01 0.0118 0.9831 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C17 mock treatment -3.0E-4 0.00568 0.02 -0.0046 8.29E-4 0.0 0.017 0.8021 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C18 mock treatment -0.0023 0.00368 0.01 -0.0036 0.00183 0.01 0.0144 0.9482 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C19 mock treatment 0.0017 0.00768 0.03 -0.0085 -0.00314 -0.01 0.0119 0.3864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C20 mock treatment -0.0073 -0.00136 -0.01 -0.0125 -0.00714 -0.03 -0.0223 -0.8269 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C21 mock treatment -3.0E-4 0.00568 0.02 -0.0175 -0.0121 -0.04 -0.017 -0.3417 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C22 mock treatment -0.0094 -0.00336 -0.01 -0.0135 -0.00814 -0.03 -0.0301 -0.9233 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C23 mock treatment -0.4519 -0.446 -1.65 -0.4523 -0.447 -1.66 -2.3369 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 C24 mock treatment -0.4509 -0.445 -1.65 -0.4523 -0.447 -1.66 -2.3343 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D01 compound treatment -0.0204 -0.0144 -0.05 -0.0195 -0.0141 -0.05 -0.0747 -1.0 2023695 DHPC5_000031 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D02 compound treatment -0.0334 -0.0274 -0.1 -0.0425 -0.0371 -0.14 -0.1689 -0.9887 2023696 DHPC5_000032 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D03 compound treatment -0.0364 -0.0304 -0.11 -0.0415 -0.0361 -0.13 -0.1741 -0.9962 2023697 DHPC5_000033 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D04 compound treatment -0.0224 -0.0164 -0.06 -0.0575 -0.0521 -0.19 -0.1795 -0.8866 2023698 DHPC5_000034 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D05 compound treatment -3.0E-4 0.00568 0.02 -5.0E-4 0.00488 0.02 0.0276 0.9972 2023699 DHPC5_000035 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D06 compound treatment -0.0083 -0.00236 -0.01 -0.0055 -1.39E-4 0.0 -0.0065 -0.7474 2023700 DHPC5_000036 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D07 compound treatment -0.0394 -0.0334 -0.12 -0.0535 -0.0481 -0.18 -0.2134 -0.9838 2023701 DHPC5_000037 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccc6OCOc6c5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D08 compound treatment -0.0424 -0.0364 -0.13 -0.0635 -0.0581 -0.22 -0.2475 -0.9743 2023702 DHPC5_000038 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccc6OCOc6c5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D09 compound treatment -0.0184 -0.0124 -0.05 -0.0026 0.00283 0.01 -0.0249 -0.531 2023703 DHPC5_000039 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D10 compound treatment -0.0043 0.00168 0.01 -0.0056 -1.69E-4 0.0 0.0039 0.6326 2023704 DHPC5_000040 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D11 mock treatment 0.0057 0.0117 0.04 0.0075 0.0128 0.05 0.0641 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D12 mock treatment 0.0037 0.00967 0.04 -0.0115 -0.00614 -0.02 0.0092 0.2172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D13 mock treatment -0.0053 6.77E-4 0.0 -0.0026 0.00283 0.01 0.0092 0.8519 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D14 mock treatment 0.0147 0.0206 0.08 -0.0095 -0.00412 -0.02 0.0432 0.5547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D15 mock treatment -0.0134 -0.00736 -0.03 -0.0175 -0.0121 -0.04 -0.051 -0.9712 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D16 mock treatment 0.0066 0.0126 0.05 -0.0046 8.31E-4 0.0 0.0352 0.7521 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D17 mock treatment 0.0097 0.0156 0.06 -0.0105 -0.00514 -0.02 0.0274 0.4504 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D18 mock treatment 0.0047 0.0107 0.04 -0.0046 8.29E-4 0.0 0.0301 0.7599 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D19 mock treatment -0.0043 0.00167 0.01 -0.0135 -0.00814 -0.03 -0.0169 -0.5505 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D20 mock treatment -0.0104 -0.00436 -0.02 -0.0026 0.00283 0.01 -0.004 -0.2073 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D21 mock treatment 0.0037 0.00968 0.04 -0.0225 -0.0171 -0.06 -0.0196 -0.2689 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D22 mock treatment -0.0043 0.00167 0.01 -5.0E-4 0.00483 0.02 0.017 0.8994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D23 mock treatment -0.4489 -0.443 -1.64 -0.4483 -0.443 -1.64 -2.3186 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 D24 mock treatment -0.4499 -0.444 -1.64 -0.4493 -0.444 -1.64 -2.3238 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E01 compound treatment -0.0164 -0.0104 -0.04 -0.0185 -0.0131 -0.05 -0.0616 -0.993 2023705 DHPC5_000041 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E02 compound treatment -0.0234 -0.0174 -0.06 -0.0255 -0.0201 -0.07 -0.0982 -0.9972 2023706 DHPC5_000042 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E03 compound treatment -0.0184 -0.0124 -0.05 -0.0265 -0.0211 -0.08 -0.0877 -0.9673 2023707 DHPC5_000043 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E04 compound treatment -0.0404 -0.0344 -0.13 -0.0485 -0.0431 -0.16 -0.203 -0.9936 2023708 DHPC5_000044 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E05 compound treatment 7.0E-4 0.00668 0.02 0.0155 0.0208 0.08 0.072 0.8889 2023709 DHPC5_000045 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E06 compound treatment 0.0087 0.0147 0.05 0.0245 0.0299 0.11 0.1166 0.9462 2023710 DHPC5_000046 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E07 compound treatment -0.0534 -0.0474 -0.18 -0.1393 -0.134 -0.5 -0.4748 -0.9022 2023711 DHPC5_000047 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccsc5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E08 compound treatment -0.0684 -0.0624 -0.23 -0.0425 -0.0371 -0.14 -0.2603 -0.9695 2023712 DHPC5_000048 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccsc5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E09 compound treatment -0.0033 0.00268 0.01 0.0045 0.00986 0.04 0.0328 0.8674 2023713 DHPC5_000049 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E10 compound treatment 0.0126 0.0186 0.07 0.0105 0.0159 0.06 0.0902 0.997 2023714 DHPC5_000050 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E11 mock treatment 0.0047 0.0107 0.04 -0.0145 -0.00914 -0.03 0.004 0.0764 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E12 mock treatment -0.0063 -3.23E-4 0.0 0.0055 0.0109 0.04 0.0276 0.6858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E13 mock treatment 0.0017 0.00768 0.03 0.0095 0.0149 0.06 0.059 0.9525 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E14 mock treatment 0.0047 0.0107 0.04 -0.0015 0.00386 0.01 0.038 0.9057 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E15 mock treatment 0.0017 0.00768 0.03 0.0235 0.0289 0.11 0.0957 0.8648 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E16 mock treatment 0.0037 0.00964 0.04 0.0014 0.00683 0.03 0.0431 0.986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E17 mock treatment 0.0147 0.0206 0.08 -0.0105 -0.00514 -0.02 0.0405 0.5149 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E18 mock treatment 0.0107 0.0166 0.06 0.0125 0.0179 0.07 0.0903 0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E19 mock treatment 0.0086 0.0146 0.05 -0.0015 0.00383 0.01 0.0483 0.8634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E20 mock treatment 0.0097 0.0156 0.06 4.0E-4 0.00583 0.02 0.0562 0.9099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E21 mock treatment 0.0117 0.0176 0.07 -6.0E-4 0.00483 0.02 0.0588 0.8691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E22 mock treatment 0.0027 0.00868 0.03 0.0084 0.0138 0.05 0.0589 0.9746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E23 mock treatment -0.4509 -0.445 -1.65 -0.4503 -0.445 -1.65 -2.329 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 E24 mock treatment -0.4489 -0.443 -1.64 -0.4493 -0.444 -1.64 -2.3212 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F01 compound treatment -0.0564 -0.0504 -0.19 -0.0455 -0.0401 -0.15 -0.2369 -0.9938 2023715 DHPC5_000051 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F02 compound treatment -0.0303 -0.0244 -0.09 -0.0175 -0.0121 -0.05 -0.0955 -0.9486 2023716 DHPC5_000052 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F03 compound treatment -0.0284 -0.0224 -0.08 -0.0235 -0.0181 -0.07 -0.106 -0.9947 2023717 DHPC5_000053 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F04 compound treatment -0.0364 -0.0304 -0.11 -0.0635 -0.0581 -0.22 -0.2319 -0.954 2023718 DHPC5_000054 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F05 compound treatment -0.0103 -0.00432 -0.02 0.0155 0.0209 0.08 0.0434 0.5493 2023719 DHPC5_000055 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F06 compound treatment 0.0086 0.0146 0.05 0.0085 0.0139 0.05 0.0746 0.9997 2023720 DHPC5_000056 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F07 compound treatment -0.0484 -0.0424 -0.16 -0.0405 -0.0351 -0.13 -0.2029 -0.9958 2023721 DHPC5_000057 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccsc5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F08 compound treatment -0.0799 -0.0739 -0.27 -0.0815 -0.0761 -0.28 -0.3927 -0.9999 2023722 DHPC5_000058 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccsc5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F09 compound treatment 0.0036 0.00959 0.04 -0.0185 -0.0131 -0.05 -0.0094 -0.1554 2023723 DHPC5_000059 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F10 compound treatment 7.0E-4 0.00668 0.02 0.0085 0.0139 0.05 0.0538 0.9435 2023724 DHPC5_000060 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F11 mock treatment 0.0017 0.00767 0.03 -0.0035 0.00186 0.01 0.0249 0.8541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F12 mock treatment -0.0063 -3.23E-4 0.0 0.0024 0.00783 0.03 0.0197 0.6774 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F13 mock treatment 0.0066 0.0126 0.05 0.0195 0.0249 0.09 0.0982 0.9504 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F14 mock treatment 0.0156 0.0216 0.08 0.0045 0.00983 0.04 0.0822 0.9369 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F15 mock treatment 0.0157 0.0216 0.08 0.0014 0.00683 0.03 0.0745 0.8875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F16 mock treatment 0.0167 0.0226 0.08 0.0125 0.0179 0.07 0.106 0.9932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F17 mock treatment 0.0086 0.0146 0.05 0.0014 0.00683 0.03 0.0562 0.94 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F18 mock treatment 0.0237 0.0296 0.11 0.0014 0.00683 0.03 0.0954 0.8481 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F19 mock treatment 0.0027 0.00868 0.03 0.0055 0.0108 0.04 0.0511 0.9938 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F20 mock treatment 0.0067 0.0127 0.05 0.0064 0.0118 0.04 0.0641 0.9994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F21 mock treatment 0.0117 0.0176 0.07 -5.0E-4 0.00483 0.02 0.0588 0.8691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F22 mock treatment 0.0086 0.0146 0.05 0.0034 0.00883 0.03 0.0614 0.9709 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F23 mock treatment -0.4489 -0.443 -1.64 -0.4513 -0.446 -1.65 -2.3264 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 F24 mock treatment -0.451 -0.445 -1.65 -0.4483 -0.443 -1.64 -2.3241 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G01 compound treatment -0.0664 -0.0604 -0.22 -0.0555 -0.0501 -0.19 -0.2894 -0.9958 2023725 DHPC5_000061 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G02 compound treatment -0.0334 -0.0274 -0.1 -0.0445 -0.0391 -0.15 -0.1742 -0.9846 2023726 DHPC5_000062 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G03 compound treatment -0.0374 -0.0314 -0.12 -0.0435 -0.0381 -0.14 -0.182 -0.9953 2023727 DHPC5_000063 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G04 compound treatment -0.0814 -0.0754 -0.28 -0.0675 -0.0621 -0.23 -0.3598 -0.9955 2023728 DHPC5_000064 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G05 compound treatment -0.0053 6.81E-4 0.0 0.0014 0.00683 0.03 0.0197 0.7736 2023729 DHPC5_000065 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G06 compound treatment -0.0033 0.00268 0.01 -0.0026 0.00283 0.01 0.0144 0.9996 2023730 DHPC5_000066 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G07 compound treatment -0.0334 -0.0274 -0.1 -0.0245 -0.0191 -0.07 -0.1217 -0.9848 2023731 DHPC5_000067 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5cccs5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G08 compound treatment -0.1079 -0.102 -0.38 -0.0895 -0.0841 -0.31 -0.4868 -0.9956 2023732 DHPC5_000068 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5cccs5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G09 compound treatment -0.0164 -0.0104 -0.04 -0.0155 -0.0101 -0.04 -0.0537 -1.0 2023733 DHPC5_000069 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G10 compound treatment 0.0017 0.00768 0.03 -0.0076 -0.00217 -0.01 0.0144 0.4878 2023734 DHPC5_000070 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G11 mock treatment 0.0017 0.00768 0.03 5.0E-4 0.00583 0.02 0.0354 0.9909 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G12 mock treatment 0.0047 0.0107 0.04 0.0055 0.0108 0.04 0.0563 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G13 mock treatment -0.0104 -0.00437 -0.02 0.0075 0.0129 0.05 0.0223 0.4429 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G14 mock treatment -0.0093 -0.00333 -0.01 -0.0066 -0.00117 0.0 -0.0118 -0.9018 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G15 mock treatment -0.0043 0.00167 0.01 0.0014 0.00683 0.03 0.0223 0.8548 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G16 mock treatment -0.0174 -0.0114 -0.04 -0.0106 -0.00517 -0.02 -0.0433 -0.9367 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G17 mock treatment -0.0053 6.77E-4 0.0 4.0E-4 0.00583 0.02 0.017 0.7838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G18 mock treatment -0.0023 0.00368 0.01 0.0055 0.0109 0.04 0.0381 0.8961 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G19 mock treatment -0.0144 -0.00836 -0.03 4.0E-4 0.00583 0.02 -0.0066 -0.1746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G20 mock treatment -0.0063 -3.23E-4 0.0 -0.0275 -0.0221 -0.08 -0.0589 -0.7173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G21 mock treatment -0.0114 -0.00536 -0.02 -0.0125 -0.00714 -0.03 -0.0327 -0.9899 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G22 mock treatment -0.0043 0.00168 0.01 -0.0145 -0.00914 -0.03 -0.0196 -0.5682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G23 mock treatment -0.4519 -0.446 -1.65 -0.4483 -0.443 -1.64 -2.3264 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 G24 mock treatment -0.4509 -0.445 -1.65 -0.4473 -0.442 -1.64 -2.3212 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H01 compound treatment -0.0384 -0.0324 -0.12 -0.0405 -0.0351 -0.13 -0.1768 -0.9991 2023735 DHPC5_000071 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H02 compound treatment -0.0294 -0.0234 -0.09 -0.0465 -0.0411 -0.15 -0.1688 -0.9639 2023736 DHPC5_000072 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2cccc(O)c2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H03 compound treatment -0.0434 -0.0374 -0.14 -0.0385 -0.0331 -0.12 -0.1847 -0.9982 2023737 DHPC5_000073 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H04 compound treatment -0.1034 -0.0974 -0.36 -0.1025 -0.0971 -0.36 -0.5091 -1.0 2023738 DHPC5_000074 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H05 compound treatment -0.0053 6.81E-4 0.0 -6.0E-4 0.00483 0.02 0.0144 0.7987 2023739 DHPC5_000075 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H06 compound treatment -0.0123 -0.00632 -0.02 -0.0046 8.29E-4 0.0 -0.0144 -0.6089 2023740 DHPC5_000076 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ncc[nH]2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H07 compound treatment -0.0284 -0.0224 -0.08 -0.0325 -0.0271 -0.1 -0.1297 -0.9954 2023741 DHPC5_000077 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5cccs5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H08 compound treatment -0.1249 -0.119 -0.44 -0.1323 -0.127 -0.47 -0.6434 -0.9994 2023742 DHPC5_000078 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NC2(CC3CC4CC(C3)C2)C4)c5cccs5 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H09 compound treatment -0.0314 -0.0254 -0.09 -0.0175 -0.0121 -0.05 -0.0983 -0.9432 2023743 DHPC5_000079 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H10 compound treatment 6.0E-4 0.00659 0.02 -0.0245 -0.0191 -0.07 -0.033 -0.4392 2023744 DHPC5_000080 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]cn2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H11 mock treatment -0.0043 0.00164 0.01 -0.0106 -0.00517 -0.02 -0.0093 -0.4611 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H12 mock treatment -0.0033 0.00268 0.01 0.0024 0.00783 0.03 0.0275 0.8975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H13 mock treatment -0.0123 -0.00632 -0.02 4.0E-4 0.00583 0.02 -0.0013 -0.0394 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H14 mock treatment 0.0047 0.0107 0.04 0.0055 0.0108 0.04 0.0563 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H15 mock treatment -0.0063 -3.23E-4 0.0 0.0015 0.00688 0.03 0.0172 0.6733 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H16 mock treatment -0.0023 0.00367 0.01 5.0E-4 0.00588 0.02 0.025 0.9741 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H17 mock treatment -0.0063 -3.26E-4 0.0 5.0E-4 0.00583 0.02 0.0144 0.6666 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H18 mock treatment -0.0114 -0.00537 -0.02 -0.0145 -0.00914 -0.03 -0.038 -0.9675 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H19 mock treatment -0.0053 6.77E-4 0.0 -0.0026 0.00283 0.01 0.0092 0.8519 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H20 mock treatment -0.0083 -0.00236 -0.01 -0.0125 -0.00714 -0.03 -0.0249 -0.8932 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H21 mock treatment -0.0073 -0.00136 -0.01 -0.0115 -0.00614 -0.02 -0.0196 -0.8433 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H22 mock treatment -3.0E-4 0.00568 0.02 -0.0065 -0.00114 0.0 0.0119 0.5539 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H23 mock treatment -0.4499 -0.444 -1.64 -0.4473 -0.442 -1.64 -2.3186 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 H24 mock treatment -0.4499 -0.444 -1.64 -0.4493 -0.444 -1.64 -2.3238 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I01 compound treatment -0.0314 -0.0254 -0.09 -0.0195 -0.0141 -0.05 -0.1033 -0.962 2020835 DHPC5_000081 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)Nc3ccccc3O)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I02 compound treatment -0.0304 -0.0244 -0.09 -0.0315 -0.0261 -0.1 -0.1322 -0.9993 2023745 DHPC5_000082 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)Nc3ccccc3O)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I03 compound treatment -0.0204 -0.0144 -0.05 0.0055 0.0109 0.04 -0.0091 -0.1367 2020833 DHPC5_000083 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)NCc3nc4ccccc4[nH]3)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I04 compound treatment -0.0844 -0.0784 -0.29 -0.0755 -0.0701 -0.26 -0.3887 -0.9985 2023746 DHPC5_000084 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)NCc3nc4ccccc4[nH]3)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I05 compound treatment -0.0214 -0.0154 -0.06 -0.0245 -0.0191 -0.07 -0.0904 -0.994 2020841 DHPC5_000085 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)N3CCCCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I06 compound treatment -0.0664 -0.0604 -0.22 -0.0625 -0.0571 -0.21 -0.3076 -0.9997 2023747 DHPC5_000086 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)N3CCCCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I07 compound treatment -0.0674 -0.0614 -0.23 -6.0E-4 0.00483 0.02 -0.1478 -0.6493 2023748 DHPC5_000087 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)N3CCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I08 compound treatment -0.0744 -0.0684 -0.25 -0.0585 -0.0531 -0.2 -0.3181 -0.9923 2023749 DHPC5_000088 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)N3CCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I09 compound treatment -0.0964 -0.0904 -0.33 -0.0635 -0.0581 -0.22 -0.3887 -0.9774 2023750 DHPC5_000089 Cc1c([C@H]2C[C@@H](OCCOCCO)OC(=C2)C(=O)NCCc3c[nH]c4ccccc34)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I10 compound treatment -0.1109 -0.105 -0.39 -0.1013 -0.0959 -0.36 -0.5257 -0.9991 2023751 DHPC5_000090 Cc1c([C@H]2C[C@@H](OCCCO)OC(=C2)C(=O)NCCc3c[nH]c4ccccc34)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I11 mock treatment 7.0E-4 0.00668 0.02 -0.0105 -0.00514 -0.02 0.004 0.1282 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I12 mock treatment -0.0073 -0.00132 0.0 0.0065 0.0118 0.04 0.0275 0.6243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I13 mock treatment -0.0013 0.00468 0.02 0.0065 0.0118 0.04 0.0432 0.9173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I14 mock treatment -0.0023 0.00368 0.01 -0.0035 0.00183 0.01 0.0144 0.9486 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I15 mock treatment -0.0094 -0.00336 -0.01 -0.0165 -0.0111 -0.04 -0.038 -0.881 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I16 mock treatment -0.0083 -0.00232 -0.01 -0.0175 -0.0121 -0.04 -0.0379 -0.8272 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I17 mock treatment -0.0193 -0.0134 -0.05 0.0095 0.0149 0.06 0.0041 0.0547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I18 mock treatment -0.0144 -0.00836 -0.03 0.0245 0.0299 0.11 0.0564 0.4908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I19 mock treatment 0.0047 0.0107 0.04 -0.0036 0.00183 0.01 0.0327 0.8167 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I20 mock treatment -0.0043 0.00168 0.01 0.0014 0.00683 0.03 0.0223 0.8551 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I21 mock treatment -0.0114 -0.00541 -0.02 0.0055 0.0108 0.04 0.0142 0.3172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I22 mock treatment 0.0047 0.0107 0.04 -0.0046 8.29E-4 0.0 0.0301 0.7599 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I23 mock treatment -0.4509 -0.445 -1.65 -0.4463 -0.441 -1.63 -2.3185 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 I24 mock treatment -0.4499 -0.444 -1.64 -0.4463 -0.441 -1.63 -2.3159 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J01 compound treatment -0.0504 -0.0444 -0.16 -0.0455 -0.0401 -0.15 -0.2213 -0.9988 2019755 DHPC5_000091 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)Nc3ccccc3O)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J02 compound treatment -0.0464 -0.0404 -0.15 -0.0295 -0.0241 -0.09 -0.1689 -0.9699 2023752 DHPC5_000092 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)Nc3ccccc3O)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J03 compound treatment -0.0854 -0.0794 -0.29 -0.0625 -0.0571 -0.21 -0.3573 -0.9871 2019753 DHPC5_000093 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)NCc3nc4ccccc4[nH]3)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J04 compound treatment -0.0664 -0.0604 -0.22 -0.0525 -0.0471 -0.17 -0.2814 -0.9926 2023753 DHPC5_000094 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)NCc3nc4ccccc4[nH]3)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J05 compound treatment -0.0624 -0.0564 -0.21 -0.0545 -0.0491 -0.18 -0.2761 -0.9977 2019761 DHPC5_000095 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)N3CCCCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J06 compound treatment -0.0724 -0.0664 -0.25 -0.0845 -0.0791 -0.29 -0.381 -0.9961 2023754 DHPC5_000096 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)N3CCCCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J07 compound treatment -0.0444 -0.0384 -0.14 -0.0445 -0.0391 -0.14 -0.2029 -0.9999 2023755 DHPC5_000097 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)N3CCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J08 compound treatment -0.0764 -0.0704 -0.26 -0.0765 -0.0711 -0.26 -0.3704 -1.0 2023756 DHPC5_000098 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)N3CCCCC3)c(=O)n(c4ccccc4)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J09 compound treatment -0.0834 -0.0774 -0.29 -0.0815 -0.0761 -0.28 -0.4018 -1.0 2023757 DHPC5_000099 Cc1c([C@@H]2C[C@H](OCCOCCO)OC(=C2)C(=O)NCCc3c[nH]c4ccccc34)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J10 compound treatment -0.0634 -0.0574 -0.21 -0.0645 -0.0591 -0.22 -0.3049 -0.9999 2023758 DHPC5_000100 Cc1c([C@@H]2C[C@H](OCCCO)OC(=C2)C(=O)NCCc3c[nH]c4ccccc34)c(=O)n(c5ccccc5)n1C 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J11 mock treatment 0.0037 0.00968 0.04 -0.0046 8.29E-4 0.0 0.0275 0.765 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J12 mock treatment -0.0013 0.00468 0.02 -0.0086 -0.00317 -0.01 0.0039 0.1879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J13 mock treatment -0.0154 -0.00937 -0.03 -0.0285 -0.0231 -0.09 -0.0851 -0.9205 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J14 mock treatment -0.0043 0.00168 0.01 -0.0116 -0.00617 -0.02 -0.0118 -0.4973 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J15 mock treatment -0.0164 -0.0104 -0.04 -0.0046 8.31E-4 0.0 -0.0249 -0.6482 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J16 mock treatment -0.0193 -0.0134 -0.05 -0.0135 -0.00814 -0.03 -0.0563 -0.972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J17 mock treatment -0.0174 -0.0114 -0.04 0.0014 0.00683 0.03 -0.0118 -0.2409 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J18 mock treatment -0.0013 0.00468 0.02 -0.0085 -0.00314 -0.01 0.004 0.1922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J19 mock treatment -0.0023 0.00368 0.01 4.0E-4 0.00583 0.02 0.0249 0.9751 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J20 mock treatment -0.0013 0.00468 0.02 0.0125 0.0179 0.07 0.059 0.8629 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J21 mock treatment 0.0087 0.0147 0.05 -0.0026 0.00283 0.01 0.0458 0.8285 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J22 mock treatment -0.0164 -0.0104 -0.04 -0.0015 0.00383 0.01 -0.0171 -0.4174 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J23 mock treatment -0.4499 -0.444 -1.64 -0.4493 -0.444 -1.64 -2.3238 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 J24 mock treatment -0.4509 -0.445 -1.65 -0.4473 -0.442 -1.64 -2.3212 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K01 compound treatment -0.0174 -0.0114 -0.04 0.0055 0.0108 0.04 -0.0014 -0.0233 2020700 DHPC5_000101 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K02 compound treatment -0.0333 -0.0274 -0.1 -0.0126 -0.00717 -0.03 -0.0903 -0.8635 2023759 DHPC5_000102 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K03 compound treatment -0.0394 -0.0334 -0.12 -0.0275 -0.0221 -0.08 -0.1454 -0.9803 2020698 DHPC5_000103 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K04 compound treatment -0.1164 -0.11 -0.41 -0.1373 -0.132 -0.49 -0.6344 -0.996 2023760 DHPC5_000104 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K05 compound treatment -0.0494 -0.0434 -0.16 -0.0315 -0.0261 -0.1 -0.1819 -0.9709 2020706 DHPC5_000105 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K06 compound treatment -0.0284 -0.0224 -0.08 -0.0245 -0.0191 -0.07 -0.1087 -0.997 2023761 DHPC5_000106 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K07 compound treatment -0.0434 -0.0374 -0.14 -0.0905 -0.0851 -0.32 -0.3207 -0.9314 2023762 DHPC5_000107 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K08 compound treatment -0.0334 -0.0274 -0.1 -0.0545 -0.0491 -0.18 -0.2003 -0.9616 2023763 DHPC5_000108 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K09 compound treatment -0.0344 -0.0284 -0.1 -0.0295 -0.0241 -0.09 -0.1374 -0.9968 2023764 DHPC5_000109 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K10 compound treatment -0.0504 -0.0444 -0.16 -0.0425 -0.0371 -0.14 -0.2134 -0.9961 2023765 DHPC5_000110 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K11 mock treatment -0.0043 0.00167 0.01 -0.0105 -0.00514 -0.02 -0.0091 -0.454 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K12 mock treatment -0.0073 -0.00132 0.0 -6.0E-4 0.00483 0.02 0.0092 0.4957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K13 mock treatment -0.0124 -0.00636 -0.02 -0.0305 -0.0251 -0.09 -0.0825 -0.8587 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K14 mock treatment -0.0053 6.77E-4 0.0 0.0084 0.0138 0.05 0.038 0.7408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K15 mock treatment -0.0054 6.27E-4 0.0 0.0014 0.00683 0.03 0.0195 0.7687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K16 mock treatment 7.0E-4 0.00668 0.02 -6.0E-4 0.00483 0.02 0.0301 0.9875 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K17 mock treatment -0.0124 -0.00637 -0.02 -0.0175 -0.0121 -0.04 -0.0484 -0.9544 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K18 mock treatment -0.0174 -0.0114 -0.04 -0.0015 0.00383 0.01 -0.0197 -0.4435 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K19 mock treatment -0.0204 -0.0144 -0.05 -0.0085 -0.00314 -0.01 -0.0458 -0.842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K20 mock treatment -0.0053 6.77E-4 0.0 -0.0175 -0.0121 -0.04 -0.03 -0.6667 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K21 mock treatment -0.0144 -0.00836 -0.03 -0.0105 -0.00514 -0.02 -0.0353 -0.9729 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K22 mock treatment 7.0E-4 0.00668 0.02 0.0014 0.00683 0.03 0.0354 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K23 mock treatment -0.4509 -0.445 -1.65 -0.4473 -0.442 -1.64 -2.3212 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 K24 mock treatment -0.4489 -0.443 -1.64 -0.4483 -0.443 -1.64 -2.3186 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L01 compound treatment -0.0074 -0.00137 -0.01 -0.0066 -0.00117 0.0 -0.0067 -0.9969 2019620 DHPC5_000111 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L02 compound treatment -3.0E-4 0.00568 0.02 -0.0026 0.00283 0.01 0.0223 0.9486 2023766 DHPC5_000112 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L03 compound treatment -0.0084 -0.00241 -0.01 -0.0085 -0.00315 -0.01 -0.0146 -0.9912 2019618 DHPC5_000113 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L04 compound treatment -0.0294 -0.0234 -0.09 -0.0205 -0.0151 -0.06 -0.1008 -0.9782 2023767 DHPC5_000114 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L05 compound treatment -0.0184 -0.0124 -0.05 -0.0145 -0.00912 -0.03 -0.0562 -0.9889 2019626 DHPC5_000115 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L06 compound treatment -0.1009 -0.0949 -0.35 -0.0783 -0.0729 -0.27 -0.4391 -0.9917 2023768 DHPC5_000116 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L07 compound treatment -0.0764 -0.0704 -0.26 -0.0615 -0.0561 -0.21 -0.3311 -0.9939 2023769 DHPC5_000117 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L08 compound treatment -0.0714 -0.0654 -0.24 -0.0575 -0.0521 -0.19 -0.3076 -0.9938 2023770 DHPC5_000118 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3ccc4OCOc4c3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L09 compound treatment -0.0494 -0.0434 -0.16 -0.0395 -0.0341 -0.13 -0.2029 -0.993 2023771 DHPC5_000119 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L10 compound treatment -0.0674 -0.0614 -0.23 -0.0015 0.00383 0.01 -0.1505 -0.6616 2023772 DHPC5_000120 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccc5OCOc5c4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L11 mock treatment 0.0107 0.0166 0.06 0.0045 0.00983 0.04 0.0693 0.9687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L12 mock treatment 0.0076 0.0136 0.05 0.0095 0.0149 0.06 0.0746 0.999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L13 mock treatment 0.0037 0.00964 0.04 0.0095 0.0149 0.06 0.0641 0.9778 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L14 mock treatment 0.0066 0.0126 0.05 0.0084 0.0138 0.05 0.0693 0.9989 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L15 mock treatment -0.0013 0.00467 0.02 0.0155 0.0209 0.08 0.0669 0.8444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L16 mock treatment 0.0066 0.0126 0.05 0.0045 0.00983 0.04 0.0588 0.9924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L17 mock treatment 0.0207 0.0266 0.1 0.0095 0.0149 0.06 0.1086 0.9623 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L18 mock treatment 0.0027 0.00868 0.03 0.0155 0.0209 0.08 0.0774 0.924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L19 mock treatment 0.0067 0.0127 0.05 0.0105 0.0159 0.06 0.0747 0.9937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L20 mock treatment 0.0086 0.0146 0.05 0.0085 0.0139 0.05 0.0746 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L21 mock treatment 0.0157 0.0216 0.08 4.0E-4 0.00583 0.02 0.0719 0.867 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L22 mock treatment 0.0167 0.0226 0.08 0.0185 0.0239 0.09 0.1217 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L23 mock treatment -0.4509 -0.445 -1.65 -0.445 -0.44 -1.63 -2.3151 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 L24 mock treatment -0.452 -0.446 -1.65 -0.447 -0.442 -1.64 -2.3233 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M01 compound treatment 0.0016 0.00759 0.03 0.0185 0.0239 0.09 0.0824 0.8878 2020727 DHPC5_000121 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M02 compound treatment -0.0224 -0.0164 -0.06 0.0075 0.0129 0.05 -0.0091 -0.1175 2023773 DHPC5_000122 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M03 compound treatment 0.0056 0.0116 0.04 -0.0035 0.00185 0.01 0.0353 0.8096 2020725 DHPC5_000123 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M04 compound treatment -0.1409 -0.135 -0.5 -0.1153 -0.11 -0.41 -0.6407 -0.9949 2023774 DHPC5_000124 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M05 compound treatment -0.0264 -0.0204 -0.08 -0.0045 8.81E-4 0.0 -0.051 -0.6758 2020733 DHPC5_000125 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M06 compound treatment -0.0434 -0.0374 -0.14 -0.0735 -0.0681 -0.25 -0.2763 -0.9599 2023775 DHPC5_000126 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M07 compound treatment -0.0784 -0.0724 -0.27 -0.0775 -0.0721 -0.27 -0.3783 -1.0 2023776 DHPC5_000127 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M08 compound treatment -0.0864 -0.0804 -0.3 -0.0745 -0.0691 -0.26 -0.3914 -0.9972 2023777 DHPC5_000128 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M09 compound treatment -0.0414 -0.0354 -0.13 -0.0385 -0.0331 -0.12 -0.1793 -0.9995 2023778 DHPC5_000129 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M10 compound treatment -0.0424 -0.0364 -0.13 -0.0455 -0.0401 -0.15 -0.2003 -0.9987 2023779 DHPC5_000130 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M11 mock treatment -0.0063 -3.26E-4 0.0 0.0125 0.0179 0.07 0.0459 0.6941 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M12 mock treatment -0.0113 -0.00532 -0.02 0.0064 0.0118 0.04 0.0171 0.3554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M13 mock treatment -3.0E-4 0.00568 0.02 0.0025 0.00786 0.03 0.0354 0.9871 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M14 mock treatment 0.0097 0.0156 0.06 0.0135 0.0188 0.07 0.0902 0.9956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M15 mock treatment -0.0094 -0.00336 -0.01 0.0095 0.0148 0.05 0.0301 0.5336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M16 mock treatment -0.0134 -0.00736 -0.03 0.0064 0.0118 0.04 0.0117 0.2276 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M17 mock treatment 0.0097 0.0156 0.06 0.0045 0.00983 0.04 0.0666 0.9752 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M18 mock treatment 0.0127 0.0186 0.07 0.0155 0.0209 0.08 0.1034 0.9984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M19 mock treatment 0.0047 0.0107 0.04 0.0165 0.0219 0.08 0.0852 0.9454 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M20 mock treatment 0.0047 0.0107 0.04 4.0E-4 0.00583 0.02 0.0432 0.9598 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M21 mock treatment 0.0117 0.0176 0.07 0.0115 0.0168 0.06 0.0902 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M22 mock treatment 0.0137 0.0196 0.07 0.0155 0.0209 0.08 0.106 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M23 mock treatment -0.4509 -0.445 -1.65 -0.4433 -0.438 -1.62 -2.3107 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 M24 mock treatment -0.4499 -0.444 -1.64 -0.4423 -0.437 -1.62 -2.3055 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N01 compound treatment -0.0064 -3.73E-4 0.0 -0.0185 -0.0131 -0.05 -0.0354 -0.7268 2019647 DHPC5_000131 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N02 compound treatment -0.0364 -0.0304 -0.11 -0.0285 -0.0231 -0.09 -0.14 -0.9911 2023780 DHPC5_000132 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N03 compound treatment -0.0263 -0.0204 -0.08 0.0014 0.00683 0.03 -0.0353 -0.4449 2019645 DHPC5_000133 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N04 compound treatment -0.0494 -0.0434 -0.16 -0.0475 -0.0421 -0.16 -0.2239 -0.9999 2023781 DHPC5_000134 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N05 compound treatment -0.0304 -0.0244 -0.09 -0.0345 -0.0291 -0.11 -0.1401 -0.9959 2019653 DHPC5_000135 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N06 compound treatment -0.0874 -0.0814 -0.3 -0.0895 -0.0841 -0.31 -0.4332 -0.9998 2023782 DHPC5_000136 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N07 compound treatment -0.0794 -0.0734 -0.27 -0.1153 -0.11 -0.41 -0.4798 -0.9805 2023783 DHPC5_000137 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N08 compound treatment -0.0384 -0.0324 -0.12 -0.0795 -0.0741 -0.27 -0.2788 -0.9307 2023784 DHPC5_000138 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3ccsc3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N09 compound treatment -0.1024 -0.0964 -0.36 -0.1423 -0.137 -0.51 -0.6108 -0.9851 2023785 DHPC5_000139 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N10 compound treatment -0.1369 -0.131 -0.48 -0.1403 -0.135 -0.5 -0.6958 -0.9999 2023786 DHPC5_000140 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4ccsc4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N11 mock treatment -0.0193 -0.0134 -0.05 -0.0095 -0.00414 -0.02 -0.0458 -0.8849 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N12 mock treatment -0.0053 6.81E-4 0.0 0.0055 0.0108 0.04 0.0302 0.75 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N13 mock treatment 7.0E-4 0.00668 0.02 0.0055 0.0109 0.04 0.0459 0.9725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N14 mock treatment -0.0063 -3.26E-4 0.0 0.0105 0.0159 0.06 0.0407 0.6925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N15 mock treatment 0.0157 0.0216 0.08 -0.0125 -0.00714 -0.03 0.0379 0.4494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N16 mock treatment 0.0027 0.00868 0.03 0.0034 0.00883 0.03 0.0458 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N17 mock treatment -0.0073 -0.00136 -0.01 4.0E-4 0.00583 0.02 0.0117 0.528 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N18 mock treatment 0.0066 0.0126 0.05 0.0105 0.0159 0.06 0.0746 0.9935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N19 mock treatment -0.0013 0.00468 0.02 -0.0095 -0.00417 -0.02 0.0013 0.0564 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N20 mock treatment 0.0086 0.0146 0.05 -0.0015 0.00383 0.01 0.0483 0.8634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N21 mock treatment 0.0116 0.0176 0.07 0.0145 0.0199 0.07 0.0981 0.9982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N22 mock treatment 0.0027 0.00868 0.03 0.0085 0.0139 0.05 0.059 0.9743 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N23 mock treatment -0.4479 -0.442 -1.63 -0.4433 -0.438 -1.62 -2.3028 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 N24 mock treatment -0.4499 -0.444 -1.64 -0.4433 -0.438 -1.62 -2.3081 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O01 compound treatment -0.0234 -0.0174 -0.06 -0.0115 -0.00615 -0.02 -0.0615 -0.9028 2023787 DHPC5_000141 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O02 compound treatment -0.0114 -0.00537 -0.02 5.0E-4 0.00588 0.02 0.0014 0.0462 2023788 DHPC5_000142 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O03 compound treatment -0.0133 -0.00732 -0.03 0.0105 0.0159 0.06 0.0225 0.3468 2023789 DHPC5_000143 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O04 compound treatment -0.0984 -0.0924 -0.34 -0.0973 -0.0919 -0.34 -0.4823 -1.0 2023790 DHPC5_000144 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O05 compound treatment -0.0294 -0.0234 -0.09 -0.0215 -0.0161 -0.06 -0.1034 -0.9836 2023791 DHPC5_000145 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O06 compound treatment -0.0264 -0.0204 -0.08 -0.0235 -0.0181 -0.07 -0.1007 -0.9984 2023792 DHPC5_000146 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O07 compound treatment -0.0394 -0.0334 -0.12 -0.0555 -0.0501 -0.19 -0.2188 -0.9803 2023793 DHPC5_000147 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O08 compound treatment -0.0404 -0.0344 -0.13 -0.0255 -0.0201 -0.07 -0.1426 -0.9677 2023794 DHPC5_000148 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)N2CCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O09 compound treatment -0.0614 -0.0554 -0.2 -0.0615 -0.0561 -0.21 -0.2918 -1.0 2023795 DHPC5_000149 OCCOCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O10 compound treatment -0.0434 -0.0374 -0.14 -0.0535 -0.0481 -0.18 -0.224 -0.9921 2023796 DHPC5_000150 OCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O11 mock treatment -0.0043 0.00168 0.01 0.0075 0.0128 0.05 0.038 0.7926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O12 mock treatment -0.0154 -0.00941 -0.03 0.0115 0.0169 0.06 0.0196 0.2736 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O13 mock treatment 0.0046 0.0106 0.04 0.0024 0.00783 0.03 0.0483 0.9888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O14 mock treatment 0.0046 0.0106 0.04 0.0074 0.0128 0.05 0.0614 0.9956 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O15 mock treatment 0.0027 0.00868 0.03 0.0245 0.0299 0.11 0.1009 0.8761 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O16 mock treatment 0.0097 0.0156 0.06 0.0034 0.00883 0.03 0.064 0.9637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O17 mock treatment 0.0056 0.0116 0.04 0.0075 0.0128 0.05 0.064 0.9988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O18 mock treatment -0.0093 -0.00332 -0.01 0.0095 0.0149 0.06 0.0303 0.5362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O19 mock treatment 7.0E-4 0.00668 0.02 -0.0016 0.00383 0.01 0.0275 0.9654 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O20 mock treatment 0.0037 0.00964 0.04 0.0125 0.0179 0.07 0.072 0.9578 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O21 mock treatment 0.0067 0.0127 0.05 0.0235 0.0289 0.11 0.1088 0.9315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O22 mock treatment 0.0097 0.0156 0.06 0.0185 0.0239 0.09 0.1034 0.9788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O23 mock treatment -0.4499 -0.444 -1.64 -0.441 -0.436 -1.61 -2.302 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 O24 mock treatment -0.4499 -0.444 -1.64 -0.4383 -0.433 -1.6 -2.295 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P01 compound treatment -0.0234 -0.0174 -0.06 -0.0325 -0.0271 -0.1 -0.1166 -0.9769 2023797 DHPC5_000151 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P02 compound treatment -0.0294 -0.0234 -0.09 -0.0175 -0.0121 -0.05 -0.093 -0.9536 2023798 DHPC5_000152 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P03 compound treatment -0.0124 -0.00637 -0.02 -0.0175 -0.0121 -0.04 -0.0485 -0.9545 2023799 DHPC5_000153 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P04 compound treatment -0.0494 -0.0434 -0.16 -0.0405 -0.0351 -0.13 -0.2056 -0.9946 2023800 DHPC5_000154 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2nc3ccccc3[nH]2)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P05 compound treatment -0.0434 -0.0374 -0.14 -0.0265 -0.0211 -0.08 -0.1532 -0.9638 2023801 DHPC5_000155 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P06 compound treatment -0.0364 -0.0304 -0.11 -0.0315 -0.0261 -0.1 -0.1479 -0.9973 2023802 DHPC5_000156 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P07 compound treatment -0.1094 -0.103 -0.38 -0.1363 -0.131 -0.49 -0.6134 -0.9931 2023803 DHPC5_000157 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P08 compound treatment -0.0554 -0.0494 -0.18 -0.0785 -0.0731 -0.27 -0.3208 -0.9815 2023804 DHPC5_000158 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCC2)c3cccs3 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P09 compound treatment -0.0434 -0.0374 -0.14 -0.0415 -0.0361 -0.13 -0.1925 -0.9999 2023805 DHPC5_000159 OCCOCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P10 compound treatment -0.1034 -0.0974 -0.36 -0.0665 -0.0611 -0.23 -0.4148 -0.975 2023806 DHPC5_000160 OCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCCc2c[nH]c3ccccc23)c4cccs4 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P11 mock treatment -0.0353 -0.0294 -0.11 -0.0265 -0.0211 -0.08 -0.1322 -0.9872 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P12 mock treatment -0.0184 -0.0124 -0.05 -0.0135 -0.00814 -0.03 -0.0536 -0.9796 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P13 mock treatment -0.0233 -0.0174 -0.06 -0.0115 -0.00614 -0.02 -0.0615 -0.9027 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P14 mock treatment -0.0164 -0.0104 -0.04 4.0E-4 0.00583 0.02 -0.0118 -0.2686 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P15 mock treatment -0.0093 -0.00332 -0.01 -0.0145 -0.00914 -0.03 -0.0326 -0.9059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P16 mock treatment -0.0184 -0.0124 -0.05 -0.0086 -0.00317 -0.01 -0.0406 -0.8608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P17 mock treatment -0.0263 -0.0204 -0.08 -5.0E-4 0.00483 0.02 -0.0406 -0.5243 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P18 mock treatment -0.0063 -3.23E-4 0.0 -0.0285 -0.0231 -0.09 -0.0615 -0.7169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P19 mock treatment -0.0093 -0.00332 -0.01 -0.0086 -0.00317 -0.01 -0.017 -0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P20 mock treatment -0.0073 -0.00132 0.0 4.0E-4 0.00583 0.02 0.0118 0.5335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P21 mock treatment 0.0066 0.0126 0.05 4.0E-4 0.00583 0.02 0.0482 0.9391 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P22 mock treatment -0.0043 0.00168 0.01 -0.0076 -0.00217 -0.01 -0.0013 -0.1278 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P23 mock treatment -0.4469 -0.441 -1.63 -0.4443 -0.439 -1.63 -2.3028 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.1337 P24 mock treatment -0.4509 -0.445 -1.65 -0.441 -0.436 -1.61 -2.3047 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A01 mock treatment -0.0307 -0.0259 -0.1 -0.0586 -0.0533 -0.2 -0.2072 -0.9447 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A02 mock treatment -0.0567 -0.0519 -0.19 -0.0796 -0.0743 -0.28 -0.3302 -0.9845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A03 mock treatment -0.09 -0.0852 -0.31 -0.0656 -0.0603 -0.22 -0.3806 -0.9858 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A04 mock treatment -0.09 -0.0852 -0.31 -0.0857 -0.0804 -0.3 -0.4333 -0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A05 mock treatment -0.0597 -0.0549 -0.2 -0.0726 -0.0673 -0.25 -0.3198 -0.9948 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A06 mock treatment -0.0847 -0.0799 -0.3 -0.0726 -0.0673 -0.25 -0.3851 -0.9964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A07 mock treatment -0.0827 -0.0779 -0.29 -0.0606 -0.0553 -0.2 -0.3485 -0.9861 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A08 mock treatment -0.0747 -0.0699 -0.26 -0.0716 -0.0663 -0.25 -0.3563 -0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A09 mock treatment -0.0537 -0.0489 -0.18 -0.0877 -0.0824 -0.31 -0.3436 -0.9688 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A10 mock treatment -0.0737 -0.0689 -0.25 -0.0786 -0.0733 -0.27 -0.372 -0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A11 mock treatment -0.0607 -0.0559 -0.21 -0.0686 -0.0633 -0.23 -0.3119 -0.998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A12 mock treatment -0.0647 -0.0599 -0.22 -0.0646 -0.0593 -0.22 -0.3118 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A13 mock treatment -0.0697 -0.0649 -0.24 -0.0816 -0.0763 -0.28 -0.3695 -0.9967 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A14 mock treatment -0.0677 -0.0629 -0.23 -0.0816 -0.0763 -0.28 -0.3642 -0.9953 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A15 mock treatment -0.0647 -0.0599 -0.22 -0.0716 -0.0663 -0.25 -0.3302 -0.9987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A16 mock treatment -0.0687 -0.0639 -0.24 -0.0796 -0.0743 -0.28 -0.3616 -0.9971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A17 mock treatment -0.0777 -0.0729 -0.27 -0.0706 -0.0653 -0.24 -0.3615 -0.9985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A18 mock treatment -0.0697 -0.0649 -0.24 -0.0696 -0.0643 -0.24 -0.338 -1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A19 mock treatment -0.0677 -0.0629 -0.23 -0.0616 -0.0563 -0.21 -0.3118 -0.9985 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A20 mock treatment -0.0807 -0.0759 -0.28 -0.0736 -0.0683 -0.25 -0.3773 -0.9987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A21 mock treatment -0.0607 -0.0559 -0.21 -0.0877 -0.0824 -0.31 -0.3619 -0.982 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A22 mock treatment -0.0747 -0.0699 -0.26 -0.0817 -0.0764 -0.28 -0.3828 -0.999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A23 mock treatment -0.0637 -0.0589 -0.22 -0.0776 -0.0723 -0.27 -0.3433 -0.9947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base A24 mock treatment -0.5767 -0.572 -2.11 -0.1177 -0.112 -0.42 -1.7897 -0.8304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B01 mock treatment -0.0047 1.52E-4 0.0 -0.0086 -0.00328 -0.01 -0.0082 -0.6737 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B02 mock treatment -7.0E-4 0.00415 0.02 0.0094 0.0147 0.05 0.0494 0.8724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B03 mock treatment 0.0193 0.0241 0.09 0.0184 0.0237 0.09 0.1252 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B04 mock treatment -7.0E-4 0.00415 0.02 0.0234 0.0287 0.11 0.0861 0.8008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B05 mock treatment 0.0083 0.0131 0.05 0.0254 0.0307 0.11 0.1149 0.928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B06 mock treatment -0.0017 0.00315 0.01 4.0E-4 0.0057 0.02 0.0232 0.9608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B07 mock treatment 0.0033 0.00815 0.03 0.0124 0.0177 0.07 0.0677 0.9377 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B08 mock treatment 0.0193 0.0241 0.09 0.0224 0.0277 0.1 0.1357 0.9975 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B09 mock treatment 0.0203 0.0251 0.09 0.0134 0.0187 0.07 0.1147 0.9896 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B10 mock treatment 0.0073 0.0121 0.04 0.0134 0.0187 0.07 0.0807 0.9777 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B11 mock treatment 0.0083 0.0132 0.05 0.0064 0.0117 0.04 0.065 0.9984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B12 mock treatment 0.0053 0.0101 0.04 0.0044 0.0097 0.04 0.0519 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B13 mock treatment 0.0203 0.0251 0.09 0.0094 0.0147 0.05 0.1042 0.9678 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B14 mock treatment 0.0033 0.00815 0.03 0.0214 0.0267 0.1 0.0913 0.8824 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B15 mock treatment 0.0043 0.00915 0.03 0.0044 0.0097 0.04 0.0493 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B16 mock treatment -0.0057 -8.49E-4 0.0 0.0124 0.0177 0.07 0.0442 0.6725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B17 mock treatment 0.0073 0.0121 0.04 0.0144 0.0197 0.07 0.0834 0.9725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B18 mock treatment 0.0043 0.00915 0.03 0.0084 0.0137 0.05 0.0599 0.9804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B19 mock treatment 0.0123 0.0171 0.06 0.0114 0.0167 0.06 0.0885 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B20 mock treatment 0.0153 0.0201 0.07 0.0074 0.0127 0.05 0.0859 0.9756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B21 mock treatment 0.0233 0.0281 0.1 0.0114 0.0167 0.06 0.1173 0.9694 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B22 mock treatment -0.0067 -0.00185 -0.01 0.0024 0.0077 0.03 0.0153 0.5226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B23 mock treatment 3.0E-4 0.00515 0.02 0.0184 0.0237 0.09 0.0756 0.8408 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base B24 mock treatment 0.0013 0.00615 0.02 0.0124 0.0177 0.07 0.0625 0.8996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C01 mock treatment -0.0047 1.51E-4 0.0 -0.0066 -0.00128 0.0 -0.003 -0.6198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C02 mock treatment -0.0077 -0.00288 -0.01 0.0024 0.0077 0.03 0.0126 0.4152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C03 mock treatment 3.0E-4 0.00515 0.02 -0.0056 -2.82E-4 0.0 0.0127 0.6673 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C04 mock treatment -0.0137 -0.00888 -0.03 0.0064 0.0117 0.04 0.0074 0.1366 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C05 mock treatment -0.0137 -0.00888 -0.03 0.0134 0.0187 0.07 0.0258 0.3362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C06 mock treatment 0.0013 0.00615 0.02 -0.0046 7.18E-4 0.0 0.018 0.7845 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C07 mock treatment 0.0033 0.00815 0.03 -0.0086 -0.00328 -0.01 0.0127 0.3911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C08 mock treatment 0.0053 0.0101 0.04 0.0074 0.0127 0.05 0.0598 0.9937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C09 mock treatment 0.0043 0.00915 0.03 0.0104 0.0157 0.06 0.0651 0.9666 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C10 mock treatment -0.0017 0.00315 0.01 -0.0066 -0.00128 0.0 0.0049 0.3879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C11 mock treatment -0.0037 0.00115 0.0 0.0014 0.0067 0.02 0.0206 0.8164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C12 mock treatment -0.0037 0.00115 0.0 0.0024 0.0077 0.03 0.0232 0.8037 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C13 mock treatment 0.0073 0.0122 0.04 -0.0036 0.0017 0.01 0.0362 0.7983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C14 mock treatment 0.0013 0.00615 0.02 -0.0076 -0.00228 -0.01 0.0101 0.4164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C15 mock treatment 0.0053 0.0101 0.04 -0.0086 -0.00328 -0.01 0.0179 0.4547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C16 mock treatment 0.0053 0.0102 0.04 0.0044 0.0097 0.04 0.052 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C17 mock treatment 0.0063 0.0111 0.04 0.0054 0.0107 0.04 0.0571 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C18 mock treatment 0.0033 0.00815 0.03 0.0054 0.0107 0.04 0.0493 0.9908 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C19 mock treatment 0.0123 0.0171 0.06 0.0014 0.0067 0.02 0.0623 0.9164 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C20 mock treatment 0.0043 0.00915 0.03 -0.0076 -0.00228 -0.01 0.0179 0.5146 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C21 mock treatment 0.0143 0.0191 0.07 -0.0066 -0.0013 0.0 0.0466 0.6573 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C22 mock treatment -0.0017 0.00315 0.01 -0.0056 -3.02E-4 0.0 0.0074 0.6363 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C23 mock treatment -0.0097 -0.00488 -0.02 -0.0096 -0.00428 -0.02 -0.024 -0.998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base C24 mock treatment -0.0057 -8.49E-4 0.0 -6.0E-4 0.00469 0.02 0.0101 0.5703 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D01 mock treatment -0.0097 -0.00488 -0.02 -0.0036 0.0017 0.01 -0.0083 -0.4348 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D02 mock treatment -7.0E-4 0.00415 0.02 4.0E-4 0.0057 0.02 0.0258 0.9877 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D03 mock treatment 0.0073 0.0122 0.04 -0.0066 -0.00128 0.0 0.0284 0.6288 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D04 mock treatment 0.0173 0.0221 0.08 -0.0156 -0.0103 -0.04 0.0309 0.3424 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D05 mock treatment -7.0E-4 0.00415 0.02 -6.0E-4 0.0047 0.02 0.0232 0.998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D06 mock treatment -0.0237 -0.0189 -0.07 -0.0036 0.00172 0.01 -0.0449 -0.64 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D07 mock treatment 0.0013 0.00615 0.02 0.0034 0.0087 0.03 0.0389 0.9854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D08 mock treatment 0.0033 0.00815 0.03 -0.0016 0.0037 0.01 0.031 0.9364 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D09 mock treatment -0.0077 -0.00288 -0.01 0.0024 0.0077 0.03 0.0126 0.4152 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D10 mock treatment -7.0E-4 0.00415 0.02 -0.0126 -0.00728 -0.03 -0.0082 -0.2651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D11 mock treatment 0.0113 0.0162 0.06 0.0154 0.0207 0.08 0.0965 0.9923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D12 mock treatment 0.0023 0.00715 0.03 -0.0066 -0.0013 0.0 0.0153 0.5687 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D13 mock treatment 0.0013 0.00615 0.02 0.0074 0.0127 0.05 0.0494 0.9444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D14 mock treatment 0.0223 0.0271 0.1 -0.0046 7.18E-4 0.0 0.0728 0.7256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D15 mock treatment -0.0037 0.00115 0.0 -0.0186 -0.0133 -0.05 -0.0318 -0.6436 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D16 mock treatment 0.0103 0.0151 0.06 -6.0E-4 0.0047 0.02 0.0518 0.8853 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D17 mock treatment 0.0143 0.0191 0.07 -0.0056 -3.03E-4 0.0 0.0492 0.6958 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D18 mock treatment 0.0013 0.00615 0.02 -0.0026 0.0027 0.01 0.0231 0.9318 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D19 mock treatment -7.0E-4 0.00415 0.02 -0.0106 -0.00528 -0.02 -0.003 -0.1201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D20 mock treatment -0.0037 0.00112 0.0 0.0034 0.0087 0.03 0.0257 0.7915 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D21 mock treatment 0.0093 0.0142 0.05 -0.0156 -0.0103 -0.04 0.0101 0.1554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D22 mock treatment -0.0027 0.00215 0.01 0.0064 0.0117 0.04 0.0363 0.8231 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D23 mock treatment 0.0103 0.0152 0.06 -0.0026 0.0027 0.01 0.0467 0.8203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base D24 mock treatment 0.0113 0.0161 0.06 0.0024 0.0077 0.03 0.0623 0.943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E01 mock treatment 0.0063 0.0111 0.04 -0.0036 0.0017 0.01 0.0335 0.8059 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E02 mock treatment 0.0083 0.0132 0.05 0.0124 0.0177 0.07 0.0808 0.9892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E03 mock treatment 0.0093 0.0141 0.05 0.0094 0.0147 0.05 0.0755 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E04 mock treatment 0.0043 0.00915 0.03 0.0124 0.0177 0.07 0.0703 0.9526 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E05 mock treatment 0.0113 0.0161 0.06 0.0154 0.0207 0.08 0.0964 0.9922 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E06 mock treatment 0.0103 0.0151 0.06 0.0194 0.0247 0.09 0.1043 0.972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E07 mock treatment 0.0133 0.0181 0.07 0.0164 0.0217 0.08 0.1043 0.9959 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E08 mock treatment 0.0063 0.0111 0.04 0.0244 0.0297 0.11 0.1069 0.9098 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E09 mock treatment 0.0073 0.0121 0.04 0.0164 0.0217 0.08 0.0886 0.9618 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E10 mock treatment 0.0183 0.0231 0.09 0.0154 0.0207 0.08 0.1147 0.9986 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E11 mock treatment 0.0083 0.0131 0.05 -0.0196 -0.0143 -0.05 -0.0031 -0.0434 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E12 mock treatment -0.0017 0.00315 0.01 0.0114 0.0167 0.06 0.052 0.8256 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E13 mock treatment 0.0083 0.0131 0.05 0.0144 0.0197 0.07 0.086 0.9804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E14 mock treatment 0.0123 0.0171 0.06 -0.0036 0.0017 0.01 0.0492 0.7736 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E15 mock treatment 0.0153 0.0201 0.07 0.0274 0.0327 0.12 0.1383 0.9725 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E16 mock treatment 0.0063 0.0111 0.04 0.0064 0.0117 0.04 0.0598 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E17 mock treatment 0.0183 0.0231 0.09 -0.0036 0.0017 0.01 0.0649 0.7571 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E18 mock treatment 0.0143 0.0191 0.07 0.0114 0.0167 0.06 0.0938 0.9978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E19 mock treatment 0.0143 0.0191 0.07 0.0024 0.0077 0.03 0.0702 0.9203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E20 mock treatment 0.0143 0.0191 0.07 0.0084 0.0137 0.05 0.0859 0.9869 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E21 mock treatment 0.0223 0.0271 0.1 0.0134 0.0187 0.07 0.1199 0.9838 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E22 mock treatment 0.0083 0.0132 0.05 0.0144 0.0197 0.07 0.086 0.9804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E23 mock treatment 0.0093 0.0142 0.05 0.0044 0.0097 0.04 0.0624 0.9832 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base E24 mock treatment 0.0263 0.0311 0.12 0.0064 0.0117 0.04 0.112 0.911 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F01 mock treatment -0.0067 -0.00188 -0.01 -0.0046 6.98E-4 0.0 -0.0031 -0.416 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F02 mock treatment -0.0107 -0.00588 -0.02 0.0064 0.0117 0.04 0.0153 0.3151 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F03 mock treatment 0.0133 0.0181 0.07 0.0034 0.0087 0.03 0.0702 0.9437 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F04 mock treatment 0.0133 0.0181 0.07 -0.0016 0.0037 0.01 0.0571 0.8345 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F05 mock treatment 0.0083 0.0131 0.05 0.0274 0.0327 0.12 0.1201 0.9194 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F06 mock treatment 0.0013 0.00615 0.02 0.0114 0.0167 0.06 0.0599 0.9075 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F07 mock treatment -0.0087 -0.00385 -0.01 0.0074 0.0127 0.05 0.0232 0.4721 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F08 mock treatment 0.0133 0.0181 0.07 0.0204 0.0257 0.1 0.1148 0.9851 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F09 mock treatment 0.0153 0.0201 0.07 -0.0116 -0.00628 -0.02 0.0361 0.4637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F10 mock treatment 0.0023 0.00715 0.03 0.0204 0.0257 0.1 0.0861 0.8704 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F11 mock treatment 0.0053 0.0102 0.04 -0.0016 0.0037 0.01 0.0362 0.9067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F12 mock treatment -0.0047 1.49E-4 0.0 0.0064 0.0117 0.04 0.0311 0.716 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F13 mock treatment 0.0153 0.0201 0.07 0.0174 0.0227 0.08 0.1121 0.9981 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F14 mock treatment 0.0203 0.0251 0.09 0.0084 0.0137 0.05 0.1016 0.9596 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F15 mock treatment 0.0303 0.0351 0.13 0.0014 0.0067 0.02 0.1094 0.8273 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F16 mock treatment 0.0223 0.0271 0.1 0.0154 0.0207 0.08 0.1252 0.9913 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F17 mock treatment 0.0173 0.0221 0.08 0.0074 0.0127 0.05 0.0911 0.9655 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F18 mock treatment 0.0273 0.0321 0.12 0.0044 0.00972 0.04 0.1094 0.8819 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F19 mock treatment 0.0113 0.0161 0.06 0.0084 0.0137 0.05 0.0781 0.9969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F20 mock treatment 0.0113 0.0161 0.06 0.0134 0.0187 0.07 0.0912 0.9972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F21 mock treatment 0.0173 0.0221 0.08 0.0074 0.0127 0.05 0.0911 0.9655 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F22 mock treatment 0.0143 0.0191 0.07 0.0084 0.0137 0.05 0.0859 0.9868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F23 mock treatment -0.0077 -0.00288 -0.01 0.0134 0.0187 0.07 0.0415 0.5916 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base F24 mock treatment 0.0243 0.0291 0.11 0.0034 0.0087 0.03 0.0989 0.8802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G01 mock treatment -0.0167 -0.0119 -0.04 0.0044 0.0097 0.04 -0.0056 -0.0995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G02 mock treatment -7.0E-4 0.00415 0.02 0.0024 0.0077 0.03 0.031 0.9577 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G03 mock treatment 0.0043 0.00915 0.03 -0.0136 -0.00828 -0.03 0.0022 0.0487 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G04 mock treatment 0.0073 0.0122 0.04 0.0104 0.0157 0.06 0.0729 0.9919 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G05 mock treatment 0.0063 0.0111 0.04 -0.0026 0.0027 0.01 0.0361 0.8541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G06 mock treatment 0.0023 0.00715 0.03 -0.0136 -0.0083 -0.03 -0.0031 -0.0755 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G07 mock treatment 0.0033 0.00815 0.03 0.0084 0.0137 0.05 0.0572 0.969 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G08 mock treatment -0.0067 -0.00185 -0.01 0.0044 0.0097 0.04 0.0206 0.5625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G09 mock treatment 0.0043 0.00915 0.03 4.0E-4 0.0057 0.02 0.0389 0.9742 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G10 mock treatment 0.0103 0.0151 0.06 4.0E-4 0.0057 0.02 0.0545 0.9113 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G11 mock treatment -0.0087 -0.00388 -0.01 -0.0106 -0.00528 -0.02 -0.024 -0.9883 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G12 mock treatment 0.0113 0.0161 0.06 0.0034 0.0087 0.03 0.0649 0.9583 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G13 mock treatment 3.0E-4 0.00511 0.02 -0.0036 0.0017 0.01 0.0178 0.8943 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G14 mock treatment -0.0047 1.51E-4 0.0 -0.0126 -0.00728 -0.03 -0.0187 -0.6923 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G15 mock treatment 0.0063 0.0112 0.04 -0.0066 -0.0013 0.0 0.0257 0.6201 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G16 mock treatment -0.0127 -0.00788 -0.03 -0.0076 -0.0023 -0.01 -0.0266 -0.8773 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G17 mock treatment 0.0063 0.0111 0.04 0.0054 0.0107 0.04 0.0572 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G18 mock treatment -0.0057 -8.49E-4 0.0 0.0044 0.0097 0.04 0.0232 0.6429 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G19 mock treatment -0.0117 -0.00688 -0.03 0.0074 0.0127 0.05 0.0153 0.2864 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G20 mock treatment 0.0043 0.00915 0.03 -0.0306 -0.0253 -0.09 -0.0423 -0.4248 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G21 mock treatment -0.0087 -0.00388 -0.01 -0.0036 0.0017 0.01 -0.0057 -0.3637 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G22 mock treatment -0.0027 0.00215 0.01 -0.0086 -0.00328 -0.01 -0.003 -0.2048 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G23 mock treatment -0.0067 -0.00188 -0.01 -0.0076 -0.00228 -0.01 -0.0109 -0.9952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base G24 mock treatment -0.0097 -0.00488 -0.02 -0.0246 -0.0193 -0.07 -0.0633 -0.8587 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H01 mock treatment -0.0137 -0.00888 -0.03 -6.0E-4 0.0047 0.02 -0.0109 -0.2935 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H02 mock treatment 0.0123 0.0171 0.06 -0.0106 -0.00528 -0.02 0.0309 0.4667 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H03 mock treatment -0.0037 0.00115 0.0 -0.0016 0.00374 0.01 0.0128 0.8836 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H04 mock treatment 0.0043 0.00915 0.03 -0.0046 7.18E-4 0.0 0.0258 0.7604 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H05 mock treatment -0.0047 1.49E-4 0.0 0.0044 0.0097 0.04 0.0258 0.7179 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H06 mock treatment -0.0147 -0.00988 -0.04 -0.0046 6.98E-4 0.0 -0.024 -0.6554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H07 mock treatment 0.0113 0.0161 0.06 0.0054 0.0107 0.04 0.0702 0.9804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H08 mock treatment -0.1987 -0.194 -0.72 -0.0076 -0.0023 -0.01 -0.5129 -0.7155 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H09 mock treatment -0.0067 -0.00185 -0.01 -0.0056 -3.02E-4 0.0 -0.0056 -0.8119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H10 mock treatment 0.0163 0.0211 0.08 -0.0046 6.98E-4 0.0 0.0571 0.7301 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H11 mock treatment 0.0023 0.00715 0.03 -0.0116 -0.00628 -0.02 0.0022 0.0634 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H12 mock treatment -0.0137 -0.00888 -0.03 -0.0026 0.0027 0.01 -0.0161 -0.4705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H13 mock treatment -0.0127 -0.00788 -0.03 -6.0E-4 0.0047 0.02 -0.0083 -0.2443 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H14 mock treatment 0.0013 0.00615 0.02 0.0024 0.0077 0.03 0.0363 0.9937 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H15 mock treatment 0.0073 0.0122 0.04 -0.0086 -0.00328 -0.01 0.0232 0.4978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H16 mock treatment -0.0017 0.00315 0.01 4.0E-4 0.0057 0.02 0.0232 0.9607 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H17 mock treatment -0.0097 -0.00488 -0.02 0.0054 0.0107 0.04 0.0153 0.3513 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H18 mock treatment -0.0167 -0.0119 -0.04 -0.0186 -0.0133 -0.05 -0.0659 -0.9984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H19 mock treatment 0.0023 0.00715 0.03 -0.0086 -0.0033 -0.01 0.01 0.3448 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H20 mock treatment -0.0057 -8.51E-4 0.0 -0.0086 -0.0033 -0.01 -0.0109 -0.8609 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H21 mock treatment -0.0047 1.51E-4 0.0 -0.0056 -3.02E-4 0.0 -4.0E-4 -0.3173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H22 mock treatment 0.0023 0.00715 0.03 -0.0036 0.0017 0.01 0.0231 0.8516 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H23 mock treatment 0.0153 0.0201 0.07 -0.0096 -0.00428 -0.02 0.0414 0.5441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base H24 mock treatment -7.0E-4 0.00415 0.02 -0.0036 0.0017 0.01 0.0153 0.9225 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I01 mock treatment -0.0077 -0.00285 -0.01 0.0074 0.0127 0.05 0.0258 0.5355 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I02 mock treatment -0.0087 -0.00385 -0.01 -0.0046 7.18E-4 0.0 -0.0082 -0.5651 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I03 mock treatment 0.0043 0.00915 0.03 0.0174 0.0227 0.08 0.0835 0.9198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I04 mock treatment -0.0057 -8.79E-4 0.0 -0.0066 -0.00126 0.0 -0.0056 -0.9842 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I05 mock treatment 0.0123 0.0171 0.06 -0.0046 6.98E-4 0.0 0.0466 0.7354 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I06 mock treatment -0.0037 0.00115 0.0 -0.0086 -0.00328 -0.01 -0.0056 -0.4336 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I07 mock treatment 0.0063 0.0111 0.04 -0.0026 0.0027 0.01 0.0361 0.8541 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I08 mock treatment -0.0117 -0.00688 -0.03 -0.0036 0.0017 0.01 -0.0135 -0.5166 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I09 mock treatment 0.0033 0.00815 0.03 0.0074 0.0127 0.05 0.0546 0.9767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I10 mock treatment 0.0123 0.0171 0.06 4.0E-4 0.00569 0.02 0.0597 0.8944 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I11 mock treatment 0.0123 0.0171 0.06 -0.0076 -0.0023 -0.01 0.0387 0.6063 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I12 mock treatment -0.0087 -0.00385 -0.01 -0.0026 0.0027 0.01 -0.003 -0.1724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I13 mock treatment 0.0013 0.00615 0.02 0.0054 0.0107 0.04 0.0442 0.965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I14 mock treatment -0.0047 1.51E-4 0.0 -0.0076 -0.0023 -0.01 -0.0056 -0.6594 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I15 mock treatment 0.0013 0.00615 0.02 -0.0206 -0.0153 -0.06 -0.024 -0.3926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I16 mock treatment -0.0117 -0.00688 -0.03 -0.0256 -0.0203 -0.08 -0.0711 -0.8965 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I17 mock treatment -0.0107 -0.00588 -0.02 0.0064 0.0117 0.04 0.0153 0.3157 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I18 mock treatment -0.0157 -0.0109 -0.04 0.0124 0.0177 0.07 0.018 0.2335 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I19 mock treatment 0.0103 0.0152 0.06 -0.0136 -0.00828 -0.03 0.0179 0.2804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I20 mock treatment -7.0E-4 0.00415 0.02 -0.0016 0.00369 0.01 0.0205 0.9984 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I21 mock treatment -0.0137 -0.00888 -0.03 0.0144 0.0197 0.07 0.0284 0.3552 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I22 mock treatment 0.0063 0.0112 0.04 -0.0046 6.98E-4 0.0 0.031 0.75 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I23 mock treatment 0.0013 0.00615 0.02 0.0074 0.0127 0.05 0.0494 0.9444 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base I24 mock treatment -0.0257 -0.0209 -0.08 -0.0066 -0.0013 0.0 -0.058 -0.7498 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J01 mock treatment -0.0207 -0.0159 -0.06 -0.0096 -0.00428 -0.02 -0.0527 -0.8671 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J02 mock treatment -0.0087 -0.00385 -0.01 -0.0296 -0.0243 -0.09 -0.0736 -0.809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J03 mock treatment -0.0237 -0.0189 -0.07 -0.0056 -2.62E-4 0.0 -0.05 -0.7169 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J04 mock treatment 3.0E-4 0.00515 0.02 4.0E-4 0.0057 0.02 0.0284 0.9987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J05 mock treatment -0.0037 0.00115 0.0 -0.0066 -0.0013 0.0 -4.0E-4 -0.0625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J06 mock treatment 0.0023 0.00715 0.03 -0.0126 -0.00728 -0.03 -4.0E-4 -0.0101 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J07 mock treatment -0.0157 -0.0109 -0.04 -0.0056 -3.03E-4 0.0 -0.0292 -0.7266 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J08 mock treatment -0.0097 -0.00485 -0.02 4.0E-4 0.0057 0.02 0.0023 0.0813 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J09 mock treatment -0.0077 -0.00285 -0.01 -0.0086 -0.0033 -0.01 -0.0161 -0.9972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J10 mock treatment -7.0E-4 0.00415 0.02 -0.0176 -0.0123 -0.05 -0.0213 -0.4441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J11 mock treatment -0.0037 0.00115 0.0 -0.0066 -0.0013 0.0 -4.0E-4 -0.0625 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J12 mock treatment -0.0017 0.00315 0.01 -0.0106 -0.0053 -0.02 -0.0057 -0.2474 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J13 mock treatment -0.0067 -0.00188 -0.01 -0.0366 -0.0313 -0.12 -0.0869 -0.7481 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J14 mock treatment -0.0047 1.49E-4 0.0 -0.0146 -0.00928 -0.03 -0.0239 -0.6957 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J15 mock treatment -0.0077 -0.00288 -0.01 -0.0086 -0.0033 -0.01 -0.0162 -0.9976 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J16 mock treatment -0.0207 -0.0159 -0.06 -0.0156 -0.0103 -0.04 -0.0685 -0.9781 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J17 mock treatment -0.0187 -0.0139 -0.05 -0.0036 0.0017 0.01 -0.0318 -0.6159 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J18 mock treatment -0.0107 -0.00585 -0.02 -0.0076 -0.0023 -0.01 -0.0213 -0.9172 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J19 mock treatment -0.0017 0.00312 0.01 0.0044 0.0097 0.04 0.0336 0.8895 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J20 mock treatment -0.0267 -0.0219 -0.08 0.0024 0.0077 0.03 -0.037 -0.4315 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J21 mock treatment 0.0093 0.0142 0.05 0.0024 0.0077 0.03 0.0572 0.9593 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J22 mock treatment -0.0197 -0.0149 -0.06 -0.0026 0.0027 0.01 -0.0318 -0.5693 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J23 mock treatment -0.0197 -0.0149 -0.06 -0.0096 -0.00428 -0.02 -0.0501 -0.8753 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base J24 mock treatment -0.0017 0.00315 0.01 -6.0E-4 0.0047 0.02 0.0205 0.9809 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K01 mock treatment -0.0067 -0.00185 -0.01 0.0104 0.0157 0.06 0.0363 0.6197 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K02 mock treatment -0.0217 -0.0169 -0.06 -0.0036 0.00172 0.01 -0.0396 -0.6317 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K03 mock treatment -0.0117 -0.00688 -0.03 -0.0016 0.0037 0.01 -0.0083 -0.2873 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K04 mock treatment -0.0057 -8.49E-4 0.0 -0.0026 0.0027 0.01 0.0048 0.4628 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K05 mock treatment 0.0043 0.00915 0.03 -0.0036 0.0017 0.01 0.0284 0.8245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K06 mock treatment -0.0067 -0.00185 -0.01 0.0014 0.0067 0.02 0.0127 0.4939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K07 mock treatment 0.0123 0.0171 0.06 -0.0336 -0.0283 -0.1 -0.0293 -0.2396 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K08 mock treatment 0.0033 0.00815 0.03 -0.0146 -0.00928 -0.03 -0.003 -0.0659 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K09 mock treatment -0.0067 -0.00185 -0.01 -0.0146 -0.00928 -0.03 -0.0292 -0.8314 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K10 mock treatment 0.0013 0.00615 0.02 -0.0026 0.0027 0.01 0.0232 0.9319 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K11 mock treatment 0.0103 0.0152 0.06 -0.0076 -0.0023 -0.01 0.0336 0.5926 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K12 mock treatment -0.0047 1.51E-4 0.0 -0.0056 -3.02E-4 0.0 -4.0E-4 -0.3173 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K13 mock treatment -0.0037 0.00115 0.0 -0.0316 -0.0263 -0.1 -0.0659 -0.6756 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K14 mock treatment -0.0067 -0.00185 -0.01 0.0014 0.0067 0.02 0.0127 0.4939 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K15 mock treatment 0.0033 0.00815 0.03 0.0044 0.0097 0.04 0.0467 0.9962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K16 mock treatment 0.0033 0.00815 0.03 0.0024 0.0077 0.03 0.0415 0.9996 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K17 mock treatment -0.0087 -0.00385 -0.01 -0.0216 -0.0163 -0.06 -0.0527 -0.8506 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K18 mock treatment -0.0177 -0.0129 -0.05 0.0054 0.0107 0.04 -0.0056 -0.0902 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K19 mock treatment -0.0147 -0.00988 -0.04 -0.0076 -0.0023 -0.01 -0.0319 -0.8494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K20 mock treatment -0.0027 0.00215 0.01 -0.0186 -0.0133 -0.05 -0.0292 -0.5852 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K21 mock treatment -0.0127 -0.00788 -0.03 -0.0036 0.0017 0.01 -0.0162 -0.542 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K22 mock treatment 3.0E-4 0.00515 0.02 0.0034 0.0087 0.03 0.0363 0.9685 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K23 mock treatment -0.0057 -8.79E-4 0.0 -0.0056 -3.02E-4 0.0 -0.0031 -0.8988 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base K24 mock treatment 0.0043 0.00915 0.03 -0.0126 -0.00728 -0.03 0.0048 0.1119 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L01 mock treatment -7.0E-4 0.00415 0.02 -0.0046 6.98E-4 0.0 0.0127 0.8148 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L02 mock treatment 0.0083 0.0131 0.05 0.0094 0.0147 0.05 0.0728 0.9983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L03 mock treatment 0.0103 0.0151 0.06 0.0094 0.0147 0.05 0.078 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L04 mock treatment 0.0053 0.0102 0.04 0.0154 0.0207 0.08 0.0808 0.9458 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L05 mock treatment 0.0133 0.0181 0.07 -0.0016 0.0037 0.01 0.0571 0.8344 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L06 mock treatment -0.0057 -8.49E-4 0.0 0.0284 0.0337 0.12 0.0861 0.6891 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L07 mock treatment -0.0017 0.00315 0.01 -0.0016 0.00369 0.01 0.0179 0.9968 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L08 mock treatment -0.0067 -0.00185 -0.01 0.0064 0.0117 0.04 0.0259 0.5885 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L09 mock treatment 0.0103 0.0151 0.06 0.0194 0.0247 0.09 0.1043 0.972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L10 mock treatment 0.0133 0.0181 0.07 -0.0096 -0.0043 -0.02 0.0361 0.5242 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L11 mock treatment 0.0143 0.0191 0.07 0.0044 0.00972 0.04 0.0755 0.951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L12 mock treatment 0.0023 0.00715 0.03 0.0024 0.00772 0.03 0.0389 0.9992 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L13 mock treatment 0.0103 0.0151 0.06 0.0074 0.0127 0.05 0.0729 0.9964 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L14 mock treatment 0.0103 0.0151 0.06 0.0044 0.0097 0.04 0.0649 0.9772 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L15 mock treatment 0.0043 0.00915 0.03 0.0084 0.0137 0.05 0.0599 0.9804 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L16 mock treatment -0.0107 -0.00586 -0.02 -0.0076 -0.00228 -0.01 -0.0213 -0.9158 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L17 mock treatment 0.0223 0.0271 0.1 0.0144 0.0197 0.07 0.1226 0.9879 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L18 mock treatment 0.0023 0.00715 0.03 0.0164 0.0217 0.08 0.0756 0.8925 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L19 mock treatment 0.0033 0.00815 0.03 0.0074 0.0127 0.05 0.0546 0.9767 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L20 mock treatment -7.0E-4 0.00415 0.02 0.0164 0.0217 0.08 0.0678 0.827 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L21 mock treatment 0.0093 0.0142 0.05 4.0E-4 0.00569 0.02 0.0519 0.9203 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L22 mock treatment 0.0113 0.0161 0.06 0.0104 0.0157 0.06 0.0833 0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L23 mock treatment 0.0143 0.0191 0.07 0.0164 0.0217 0.08 0.1069 0.9979 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base L24 mock treatment 0.0253 0.0301 0.11 0.0234 0.0287 0.11 0.154 0.9997 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M01 mock treatment 0.0113 0.0161 0.06 0.0134 0.0187 0.07 0.0912 0.9971 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M02 mock treatment 0.0053 0.0102 0.04 0.0184 0.0237 0.09 0.0887 0.928 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M03 mock treatment 0.0213 0.0261 0.1 0.0054 0.0107 0.04 0.0963 0.9226 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M04 mock treatment 0.0083 0.0131 0.05 0.0184 0.0237 0.09 0.0965 0.9608 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M05 mock treatment 0.0143 0.0191 0.07 0.0064 0.0117 0.04 0.0806 0.9724 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M06 mock treatment 0.0063 0.0112 0.04 0.0124 0.0177 0.07 0.0756 0.9749 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M07 mock treatment 0.0113 0.0161 0.06 0.0024 0.0077 0.03 0.0623 0.9431 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M08 mock treatment -0.0037 0.00115 0.0 0.0024 0.0077 0.03 0.0232 0.8038 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M09 mock treatment 0.0103 0.0151 0.06 0.0014 0.0067 0.02 0.0571 0.9332 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M10 mock treatment -0.0187 -0.0139 -0.05 -0.0156 -0.0103 -0.04 -0.0632 -0.9892 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M11 mock treatment -0.0057 -8.48E-4 0.0 0.0114 0.0167 0.06 0.0416 0.6705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M12 mock treatment -0.0057 -8.49E-4 0.0 0.0024 0.0077 0.03 0.0179 0.6255 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M13 mock treatment 3.0E-4 0.00515 0.02 -0.0056 -3.04E-4 0.0 0.0127 0.6641 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M14 mock treatment 0.0073 0.0121 0.04 0.0034 0.0087 0.03 0.0545 0.987 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M15 mock treatment -0.0077 -0.00285 -0.01 -0.0016 0.00369 0.01 0.0022 0.1289 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M16 mock treatment -0.0217 -0.0169 -0.06 -0.0016 0.0037 0.01 -0.0344 -0.539 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M17 mock treatment 0.0153 0.0201 0.07 -0.0016 0.0037 0.01 0.0623 0.8235 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M18 mock treatment 0.0143 0.0191 0.07 0.0134 0.0187 0.07 0.099 1.0 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M19 mock treatment 0.0013 0.00615 0.02 0.0154 0.0207 0.08 0.0704 0.8788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M20 mock treatment 0.0043 0.00915 0.03 -0.0036 0.0017 0.01 0.0284 0.8245 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M21 mock treatment 0.0123 0.0171 0.06 0.0054 0.0107 0.04 0.0728 0.9746 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M22 mock treatment 0.0103 0.0152 0.06 0.0104 0.0157 0.06 0.0808 0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M23 mock treatment -0.0037 0.00115 0.0 0.0104 0.0157 0.06 0.0442 0.7568 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base M24 mock treatment -0.0057 -8.51E-4 0.0 -0.0136 -0.0083 -0.03 -0.024 -0.7754 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N01 mock treatment -7.0E-4 0.00415 0.02 -0.0176 -0.0123 -0.05 -0.0213 -0.4441 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N02 mock treatment -0.0117 -0.00685 -0.03 -0.0236 -0.0183 -0.07 -0.0658 -0.9099 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N03 mock treatment -0.0137 -0.00888 -0.03 0.0104 0.0157 0.06 0.0179 0.2682 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N04 mock treatment -0.0157 -0.0109 -0.04 -0.0046 6.98E-4 0.0 -0.0266 -0.6603 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N05 mock treatment 0.0103 0.0151 0.06 -0.0076 -0.0023 -0.01 0.0335 0.5924 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N06 mock treatment -0.0037 0.00115 0.0 -0.0096 -0.0043 -0.02 -0.0083 -0.5008 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N07 mock treatment 0.0013 0.00615 0.02 -0.0196 -0.0143 -0.05 -0.0213 -0.3705 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N08 mock treatment -0.0057 -8.48E-4 0.0 -0.0306 -0.0253 -0.09 -0.0685 -0.7304 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N09 mock treatment -0.0287 -0.0239 -0.09 -0.0376 -0.0323 -0.12 -0.147 -0.9888 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N10 mock treatment 0.0033 0.00815 0.03 -0.0056 -3.04E-4 0.0 0.0205 0.6802 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N11 mock treatment -0.0217 -0.0169 -0.06 -0.0156 -0.0103 -0.04 -0.0711 -0.972 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N12 mock treatment -7.0E-4 0.00415 0.02 -6.0E-4 0.00474 0.02 0.0233 0.9978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N13 mock treatment -0.0077 -0.00285 -0.01 -0.0046 6.98E-4 0.0 -0.0056 -0.5181 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N14 mock treatment -0.0087 -0.00385 -0.01 0.0034 0.00872 0.03 0.0128 0.362 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N15 mock treatment 0.0133 0.0181 0.07 -0.0176 -0.0123 -0.05 0.0152 0.1876 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N16 mock treatment -0.0097 -0.00485 -0.02 -0.0016 0.0037 0.01 -0.003 -0.1327 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N17 mock treatment -0.0147 -0.00988 -0.04 -0.0086 -0.0033 -0.01 -0.0345 -0.8951 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N18 mock treatment -0.0037 0.00115 0.0 0.0054 0.0107 0.04 0.0311 0.7783 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N19 mock treatment -0.0187 -0.0139 -0.05 -0.0136 -0.0083 -0.03 -0.058 -0.97 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N20 mock treatment 0.0053 0.0102 0.04 -0.0016 0.0037 0.01 0.0362 0.9067 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N21 mock treatment 3.0E-4 0.00515 0.02 0.0174 0.0227 0.08 0.073 0.8457 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N22 mock treatment -0.0277 -0.0229 -0.08 0.0014 0.0067 0.02 -0.0422 -0.4792 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N23 mock treatment 3.0E-4 0.00511 0.02 0.0044 0.00972 0.04 0.0388 0.9547 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base N24 mock treatment 0.0063 0.0111 0.04 0.0074 0.0127 0.05 0.0625 0.9978 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O01 mock treatment 0.0023 0.00711 0.03 -6.0E-4 0.0047 0.02 0.0309 0.98 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O02 mock treatment 0.0063 0.0111 0.04 0.0144 0.0197 0.07 0.0807 0.963 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O03 mock treatment -0.0037 0.00115 0.0 0.0044 0.0097 0.04 0.0284 0.7854 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O04 mock treatment 0.0103 0.0152 0.06 0.0074 0.0127 0.05 0.0729 0.9962 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O05 mock treatment 0.0083 0.0131 0.05 0.0054 0.0107 0.04 0.0623 0.995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O06 mock treatment 3.0E-4 0.00515 0.02 0.0134 0.0187 0.07 0.0625 0.8691 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O07 mock treatment 0.0173 0.0221 0.08 -0.0106 -0.0053 -0.02 0.0439 0.5224 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O08 mock treatment -7.0E-4 0.00415 0.02 0.0164 0.0217 0.08 0.0678 0.8271 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O09 mock treatment 0.0023 0.00715 0.03 0.0014 0.0067 0.02 0.0362 0.9995 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O10 mock treatment -0.0147 -0.00988 -0.04 -0.0076 -0.0023 -0.01 -0.0319 -0.8494 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O11 mock treatment -0.0037 0.00115 0.0 4.0E-4 0.0057 0.02 0.0179 0.8329 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O12 mock treatment -0.0127 -0.00788 -0.03 0.0014 0.0067 0.02 -0.0031 -0.0798 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O13 mock treatment 0.0023 0.00715 0.03 -0.0086 -0.0033 -0.01 0.01 0.3448 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O14 mock treatment 0.0023 0.00715 0.03 0.0034 0.0087 0.03 0.0415 0.9952 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O15 mock treatment 0.0043 0.00915 0.03 0.0204 0.0257 0.1 0.0913 0.9029 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O16 mock treatment 0.0133 0.0181 0.07 -0.0046 6.98E-4 0.0 0.0492 0.7339 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O17 mock treatment 0.0053 0.0101 0.04 0.0014 0.0067 0.02 0.044 0.9801 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O18 mock treatment -0.0137 -0.00888 -0.03 0.0034 0.00872 0.03 -4.0E-4 -0.0082 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O19 mock treatment -0.0087 -0.00385 -0.01 -0.0036 0.0017 0.01 -0.0056 -0.361 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O20 mock treatment -0.0067 -0.00185 -0.01 -0.0246 -0.0193 -0.07 -0.0554 -0.7712 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O21 mock treatment 3.0E-4 0.00515 0.02 0.0154 0.0207 0.08 0.0677 0.8565 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O22 mock treatment 0.0073 0.0121 0.04 0.0154 0.0207 0.08 0.086 0.9672 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O23 mock treatment -0.0107 -0.00588 -0.02 0.0204 0.0257 0.1 0.052 0.5321 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base O24 mock treatment -0.0147 -0.00988 -0.04 -0.0046 6.98E-4 0.0 -0.024 -0.6554 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P01 mock treatment -0.0187 -0.0139 -0.05 -0.0286 -0.0233 -0.09 -0.0973 -0.9692 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P02 mock treatment -0.0147 -0.00985 -0.04 -0.0046 7.18E-4 0.0 -0.0239 -0.6537 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P03 mock treatment 3.0E-4 0.00515 0.02 -0.0196 -0.0143 -0.05 -0.024 -0.4259 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P04 mock treatment -0.0147 -0.00988 -0.04 -0.0156 -0.0103 -0.04 -0.0528 -0.9998 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P05 mock treatment -0.0207 -0.0159 -0.06 -0.0146 -0.00928 -0.03 -0.0658 -0.9676 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P06 mock treatment -0.0237 -0.0189 -0.07 -0.0066 -0.0013 0.0 -0.0528 -0.7542 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P07 mock treatment -0.0227 -0.0179 -0.07 -0.0326 -0.0273 -0.1 -0.1182 -0.9788 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P08 mock treatment -0.0057 -8.51E-4 0.0 -0.0226 -0.0173 -0.06 -0.0475 -0.741 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P09 mock treatment -0.0257 -0.0209 -0.08 -0.0196 -0.0143 -0.05 -0.092 -0.983 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P10 mock treatment -0.0277 -0.0229 -0.08 -0.0276 -0.0223 -0.08 -0.1182 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P11 mock treatment -0.0397 -0.0349 -0.13 -0.0336 -0.0283 -0.1 -0.1653 -0.9947 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P12 mock treatment -0.0237 -0.0189 -0.07 -0.0256 -0.0203 -0.08 -0.1025 -0.9993 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P13 mock treatment -0.0377 -0.0329 -0.12 -0.0156 -0.0103 -0.04 -0.1129 -0.8862 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P14 mock treatment -0.0217 -0.0169 -0.06 -0.0056 -3.04E-4 0.0 -0.0449 -0.7198 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P15 mock treatment -0.0187 -0.0139 -0.05 -0.0246 -0.0193 -0.07 -0.0868 -0.9868 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P16 mock treatment -0.0217 -0.0169 -0.06 -0.0226 -0.0173 -0.06 -0.0894 -0.9999 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P17 mock treatment -0.0397 -0.0349 -0.13 -0.0126 -0.0073 -0.03 -0.1103 -0.8372 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P18 mock treatment -0.0117 -0.00685 -0.03 -0.0276 -0.0223 -0.08 -0.0763 -0.8834 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P19 mock treatment -0.0207 -0.0159 -0.06 -0.0176 -0.0123 -0.05 -0.0737 -0.9921 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P20 mock treatment -0.0157 -0.0109 -0.04 -0.0126 -0.0073 -0.03 -0.0476 -0.9814 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P21 mock treatment -0.0067 -0.00185 -0.01 -0.0076 -0.0023 -0.01 -0.0109 -0.994 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P22 mock treatment -0.0147 -0.00988 -0.04 -0.0196 -0.0143 -0.05 -0.0633 -0.9835 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P23 mock treatment -0.0097 -0.00488 -0.02 -0.0306 -0.0253 -0.09 -0.079 -0.8281 1021.0016 Calc(E1-E2)(1021.0016) DihydroorotateDehydrogenase 1021.0016.Base P24 mock treatment -0.0137 -0.00888 -0.03 0.0134 0.0187 0.07 0.0259 0.337