ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A01 mock treatment 0.342 -0.00365 -0.3 0.339 -0.00309 -0.27 -0.4079 -0.9988 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A02 mock treatment 0.347 0.00135 0.11 0.354 0.0119 1.06 0.8256 0.7781 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A03 compound treatment 0.34 -0.00565 -0.47 0.339 -0.00309 -0.27 -0.5253 -0.9674 1513241 CBMicro_030081 O=C(CSc1nnnn1c2ccccc2)N3c4ccccc4Sc5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A04 compound treatment 0.346 3.55E-4 0.03 0.342 -9.37E-5 -0.01 0.015 0.4886 1940634 CBMicro_030082 Cc1sc2nc(SCC(=O)NCCO)[nH]c(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A05 compound treatment 0.328 -0.0176 -1.46 0.325 -0.0171 -1.51 -2.107 -0.9999 1589114 CBMicro_030083 CC(C)c1cc(NS(=O)(=O)c2ccc(Cl)cc2)cc(C(C)C)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A06 compound treatment 0.36 0.0144 1.19 0.365 0.0229 2.03 2.2781 0.9678 1940635 CBMicro_030084 Brc1ccc(cc1)N(CC(=O)NCCOc2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A07 compound treatment 0.344 -0.00165 -0.14 0.353 0.0109 0.97 0.5869 0.6012 1940636 CBMicro_030085 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A08 compound treatment 0.267 -0.0786 -6.53 0.253 -0.0891 -7.9 -10.1998 -0.9955 1940637 CBMicro_030086 [O-][N+](=O)c1ccc(o1)C(=O)/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A09 compound treatment 0.335 -0.0106 -0.88 0.331 -0.0111 -0.98 -1.3201 -0.9986 1940638 CBMicro_030087 C=CCSc1nnc2sc3ccccc3n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A10 compound treatment 0.343 -0.00265 -0.22 0.338 -0.00409 -0.36 -0.4118 -0.9711 1366099 CBMicro_030088 CCc1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A11 compound treatment 0.458 0.112 9.33 0.468 0.126 11.16 14.4855 0.996 1940639 CBMicro_030089 O=C(Nc1ccc(cc1)C(=O)/C=C/c2cccc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A12 compound treatment 0.345 -6.45E-4 -0.05 0.341 -0.00109 -0.1 -0.1064 -0.9609 1149566 CBMicro_030090 COc1ccccc1C(=O)Nc2nc[nH]n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A13 compound treatment 0.388 0.0424 3.52 0.376 0.0339 3.0 4.6111 0.9969 1940640 CBMicro_030091 O=C(Nc1ccc(NC(=O)c2ccco2)cc1)/C=C\c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A14 compound treatment 0.34 -0.00565 -0.47 0.326 -0.0161 -1.43 -1.3399 -0.8925 1442838 CBMicro_030092 Cc1cc(OCC(=O)OCc2ccccc2)c3c4CCCCc4c(=O)oc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A15 compound treatment 0.319 -0.0266 -2.21 0.317 -0.0251 -2.22 -3.1367 -1.0 1940641 CBMicro_030093 CC/1=CC(=O)C=C\C1=N/S(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A16 compound treatment 0.343 -0.00265 -0.22 0.345 0.00291 0.26 0.0268 0.0793 1440360 CBMicro_030094 CC(=O)NC(c1ccc2OCOc2c1)c3ccc4cccnc4c3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A17 compound treatment 0.422 0.0764 6.34 0.406 0.0639 5.66 8.487 0.9984 1268225 CBMicro_030095 Cc1cccc(N2C(=O)c3ccc(NC(=O)C(c4ccccc4)c5ccccc5)cc3C2=O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A18 compound treatment 0.343 -0.00265 -0.22 0.342 -9.37E-5 -0.01 -0.1612 -0.7333 1492474 CBMicro_030096 COc1ccc(CCC(=O)NCCc2ccc(OC)c(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A19 compound treatment 0.304 -0.0416 -3.46 0.3 -0.0421 -3.73 -5.0825 -0.9993 1940642 CBMicro_030097 Cc1ccc(cc1)S(=O)(=O)/N=C\2/C=C(Sc3nnnn3c4ccccc4)C(=O)c5ccccc25 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A20 compound treatment 0.347 0.00135 0.11 0.351 0.00891 0.79 0.6376 0.7998 1128797 CBMicro_030098 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A21 compound treatment 0.378 0.0324 2.69 0.375 0.0329 2.92 3.9614 0.9992 1783492 CBMicro_030099 Cc1nccn1c2c([N+](=O)[O-])c(=O)n(C)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A22 compound treatment 0.345 -6.45E-4 -0.05 0.338 -0.00409 -0.36 -0.2944 -0.8028 1940643 CBMicro_030100 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3cccc(c3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A23 positive control 0.085 -0.261 -21.64 0.084 -0.258 -22.87 -31.4742 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 A24 positive control 0.085 -0.261 -21.64 0.087 -0.255 -22.61 -31.2862 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B01 mock treatment 0.341 -0.00465 -0.39 0.333 -0.00909 -0.81 -0.8425 -0.9431 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B02 mock treatment 0.35 0.00435 0.36 0.342 -9.37E-5 -0.01 0.2498 0.6907 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B03 compound treatment 0.339 -0.00665 -0.55 0.335 -0.00709 -0.63 -0.8346 -0.9979 1210492 CBMicro_030101 CCOc1ccc(cc1)C(=O)NCc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B04 compound treatment 0.331 -0.0146 -1.22 0.326 -0.0161 -1.43 -1.8682 -0.9968 1414827 CBMicro_030102 COC(=O)c1cccc(NC(=O)COc2ccc(Br)c(C)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B05 compound treatment 0.394 0.0484 4.01 0.397 0.0549 4.87 6.2793 0.9954 1476660 CBMicro_030103 COc1ccc(cc1)c2cc(C(=O)Nc3ccccc3Br)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B06 compound treatment 0.344 -0.00165 -0.14 0.339 -0.00309 -0.27 -0.2904 -0.9482 1278115 CBMicro_030104 COc1ccc2nc(NC(=O)c3ccccc3O)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B07 compound treatment 0.345 -6.45E-4 -0.05 0.338 -0.00409 -0.36 -0.2944 -0.8028 1940644 CBMicro_030105 CC(=O)c1cccc(NC(=O)COc2ccc(cc2)C(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B08 compound treatment 0.34 -0.00565 -0.47 0.335 -0.00709 -0.63 -0.7759 -0.9895 1148308 CBMicro_030106 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B09 compound treatment 0.304 -0.0416 -3.46 0.298 -0.0441 -3.91 -5.2078 -0.9981 1443854 CBMicro_030107 Cc1ccc(cc1)S(=O)(=O)Nc2cc(Cl)c(O)c(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B10 compound treatment 0.279 -0.0666 -5.53 0.304 -0.0381 -3.38 -6.2994 -0.9719 1940645 CBMicro_030108 Cc1ccc(cc1)C(=O)/C=C/c2ccc(o2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B11 compound treatment 0.356 0.0104 0.86 0.355 0.0129 1.14 1.4166 0.9901 1940646 CBMicro_030109 COc1cc(OC)cc(c1)C(=O)Nc2ccc(cn2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B12 compound treatment 0.438 0.0924 7.67 0.415 0.0729 6.46 9.9902 0.9964 1940647 CBMicro_030110 CCN(CC)c1ccc(/C=N/NC(=O)CSc2nc3ccccc3n2Cc4ccccc4)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B13 compound treatment 0.339 -0.00665 -0.55 0.342 -9.37E-5 -0.01 -0.396 -0.7177 1940648 CBMicro_030111 Brc1ccc2nc(NC(=O)/C=C/c3ccco3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B14 compound treatment 0.325 -0.0206 -1.71 0.323 -0.0191 -1.69 -2.4085 -1.0 1390170 CBMicro_030112 CCc1ccccc1NC(=O)c2cc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B15 compound treatment 0.368 0.0224 1.86 0.361 0.0189 1.68 2.4971 0.9987 1940649 CBMicro_030113 Cc1ccc(OCC(=O)Nc2ncc(s2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-])c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B16 compound treatment 0.339 -0.00665 -0.55 0.335 -0.00709 -0.63 -0.8346 -0.9979 1269973 CBMicro_030114 O=C(Oc1cc(c2ccccc2)c3oc(=O)sc3c1)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B17 compound treatment 0.338 -0.00765 -0.63 0.344 0.00191 0.17 -0.3293 -0.5014 1940650 CBMicro_030115 C(Sc1nncn1/N=C/c2ccco2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B18 compound treatment 0.342 -0.00365 -0.3 0.334 -0.00809 -0.72 -0.7212 -0.9264 1327424 CBMicro_030116 COC(=O)c1cc(Cl)c(NC(=O)COc2ccc(C)cc2C(C)(C)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B19 compound treatment 0.338 -0.00765 -0.63 0.336 -0.00609 -0.54 -0.8307 -0.9968 1678022 CBMicro_030117 CC(C)OC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B20 compound treatment 0.343 -0.00265 -0.22 0.334 -0.00809 -0.72 -0.6625 -0.8831 1940651 CBMicro_030118 COC(=O)C(C)NC(=O)CCC1CCCCC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B21 compound treatment 0.343 -0.00265 -0.22 0.339 -0.00309 -0.27 -0.3491 -0.9939 1940652 CBMicro_030119 CC(=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B22 compound treatment 0.335 -0.0106 -0.88 0.334 -0.00809 -0.72 -1.1321 -0.9946 1376079 CBMicro_030120 Fc1cccc(NC(=O)C2CN(C(=O)C2)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B23 positive control 0.082 -0.264 -21.89 0.084 -0.258 -22.87 -31.6503 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 B24 positive control 0.084 -0.262 -21.72 0.086 -0.256 -22.7 -31.4076 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C01 mock treatment 0.34 -0.00565 -0.47 0.338 -0.00409 -0.36 -0.5879 -0.992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C02 mock treatment 0.355 0.00935 0.78 0.348 0.00591 0.52 0.9193 0.9816 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C03 compound treatment 0.342 -0.00365 -0.3 0.34 -0.00209 -0.19 -0.3452 -0.9724 1354807 CBMicro_030121 Cc1cc(C)nc(SCC(=O)Nc2nncs2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C04 compound treatment 0.344 -0.00165 -0.14 0.345 0.00291 0.26 0.0855 0.2934 1278611 CBMicro_030122 COc1ccc(NC(=O)C2CCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C05 compound treatment 0.344 -0.00165 -0.14 0.339 -0.00309 -0.27 -0.2904 -0.9482 1500945 CBMicro_030123 OCCOc1ccc2c3CCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C06 compound treatment 0.356 0.0104 0.86 0.366 0.0239 2.12 2.106 0.9211 1417155 CBMicro_030124 CCc1nnc(NC(=O)CC(c2ccccc2)c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C07 compound treatment 0.395 0.0494 4.1 0.391 0.0489 4.33 5.962 0.9996 1040656 CBMicro_030125 CCOC(=O)c1cc2cc(ccc2oc1=O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C08 compound treatment 0.344 -0.00165 -0.14 0.34 -0.00209 -0.19 -0.2278 -0.9886 1940653 CBMicro_030126 Cc1ccc(/C=C/C(=O)c2ccc(cc2)[N+](=O)[O-])s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C09 compound treatment 0.33 -0.0156 -1.3 0.319 -0.0231 -2.05 -2.3656 -0.9759 1940654 CBMicro_030127 CC(C)C1=CC(=NS(=O)(=O)c2ccc(Cl)cc2)C=C(C(C)C)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C10 compound treatment 0.378 0.0324 2.69 0.379 0.0369 3.27 4.2121 0.9952 1940655 CBMicro_030128 Cn1c(=O)c([N+](=O)[O-])c(NCc2ccccc2)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C11 compound treatment 0.341 -0.00465 -0.39 0.338 -0.00409 -0.36 -0.5292 -0.9995 1149864 CBMicro_030129 Cc1cc(OCC(=O)NCc2ccco2)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C12 compound treatment 0.36 0.0144 1.19 0.355 0.0129 1.14 1.6514 0.9998 1567971 CBMicro_030130 Cc1ccc(cc1)c2csc(NC(=O)C3(CC4CC5CC(C4)C3)C5)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C13 compound treatment 0.335 -0.0106 -0.88 0.329 -0.0131 -1.16 -1.4454 -0.991 1940656 CBMicro_030131 Cc1cnnn1c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C14 compound treatment 0.347 0.00135 0.11 0.338 -0.00409 -0.36 -0.177 -0.466 1940657 CBMicro_030132 CCOc1ccccc1C(=O)Nc2ccc(Cl)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C15 compound treatment 0.331 -0.0146 -1.22 0.321 -0.0211 -1.87 -2.1816 -0.9783 1284688 CBMicro_030133 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C16 compound treatment 0.341 -0.00465 -0.39 0.339 -0.00309 -0.27 -0.4666 -0.986 1601164 CBMicro_030134 Cc1cccc2sc(NC(=O)c3ccc(cc3)C(=O)c4ccccc4)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C17 compound treatment 0.625 0.279 23.19 0.65 0.308 27.29 35.694 0.9967 1940658 CBMicro_030135 COc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C18 compound treatment 0.349 0.00335 0.28 0.348 0.00591 0.52 0.5671 0.9564 1940659 CBMicro_030136 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2ccco2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C19 compound treatment 0.336 -0.00965 -0.8 0.339 -0.00309 -0.27 -0.7601 -0.898 1940660 CBMicro_030137 CC(=C)CSc1nnc2nc(C)cc(C)n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C20 compound treatment 0.343 -0.00265 -0.22 0.341 -0.00109 -0.1 -0.2238 -0.9324 1940661 CBMicro_030138 Cc1cc(O)nc(SCC(=O)Nc2ccccc2[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C21 compound treatment 0.34 -0.00565 -0.47 0.338 -0.00409 -0.36 -0.5879 -0.992 1940662 CBMicro_030139 CCOC(=O)c1c(C)c(C)sc1NC(=O)/C=C/c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C22 compound treatment 0.336 -0.00965 -0.8 0.337 -0.00509 -0.45 -0.8854 -0.9632 1206447 CBMicro_030140 COc1ccc(cc1OC)C(=O)Nc2sc(C(=O)OC(C)C)c(C)c2C(=O)OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C23 positive control 0.081 -0.265 -21.97 0.082 -0.26 -23.05 -31.8343 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 C24 positive control 0.081 -0.265 -21.97 0.087 -0.255 -22.61 -31.521 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D01 mock treatment 0.347 0.00135 0.11 0.344 0.00191 0.17 0.199 0.9805 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D02 mock treatment 0.347 0.00135 0.11 0.343 9.06E-4 0.08 0.1363 0.9864 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D03 compound treatment 0.346 3.55E-4 0.03 0.341 -0.00109 -0.1 -0.0477 -0.4709 1479426 CBMicro_030141 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Br)cc2)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D04 compound treatment 0.341 -0.00465 -0.39 0.343 9.06E-4 0.08 -0.2159 -0.5481 1864224 CBMicro_030142 CCOC(=O)c1sc(NC(=O)CCN2C(=O)c3cccc([N+](=O)[O-])c3C2=O)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D05 compound treatment 0.38 0.0344 2.85 0.37 0.0279 2.47 3.7655 0.9975 1209048 CBMicro_030143 CCOC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D06 compound treatment 0.331 -0.0146 -1.22 0.33 -0.0121 -1.07 -1.6176 -0.998 1940663 CBMicro_030144 CC1CN=C(Nc2ccc(Cl)cc2C)S1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D07 compound treatment 0.321 -0.0246 -2.05 0.307 -0.0351 -3.11 -3.6459 -0.9794 1607806 CBMicro_030145 COc1cccc(NC(=O)COc2ccc(cc2)C(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D08 compound treatment 0.34 -0.00565 -0.47 0.352 0.00991 0.88 0.2894 0.2908 1940664 CBMicro_030146 COc1cc(OC)cc(c1)C(=O)Nc2ccc(cc2OC)c3ccc(NC(=O)c4cc(OC)cc(OC)c4)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D09 compound treatment 0.097 -0.249 -20.64 0.087 -0.255 -22.61 -30.5818 -0.999 1940665 CBMicro_030147 CC1=C/C(=N/S(=O)(=O)c2ccc(C)cc2)/C=C(Cl)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D10 compound treatment 0.523 0.177 14.72 0.506 0.164 14.53 20.6825 1.0 1940666 CBMicro_030148 O=C(/C=C\Nc1ccccn1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D11 compound treatment 0.348 0.00235 0.2 0.35 0.00791 0.7 0.6337 0.8711 1222074 CBMicro_030149 CC(Oc1ccc(Cl)cc1Cl)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D12 compound treatment 0.34 -0.00565 -0.47 0.338 -0.00409 -0.36 -0.5879 -0.992 1940667 CBMicro_030150 CCn1c(SCC(=O)N/N=C/c2cccc(CC=C)c2O)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D13 compound treatment 0.365 0.0194 1.61 0.357 0.0149 1.32 2.0703 0.9953 1263214 CBMicro_030151 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D14 compound treatment 0.342 -0.00365 -0.3 0.332 -0.0101 -0.89 -0.8465 -0.8964 1569257 CBMicro_030152 COC(=O)c1cccc(NC(=O)c2c(Cl)ccc(Cl)c2OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D15 compound treatment 0.359 0.0134 1.11 0.345 0.00291 0.26 0.9661 0.8488 1940668 CBMicro_030153 CC(=O)c1cccc(NC(=O)Nc2ccc(C)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D16 compound treatment 0.347 0.00135 0.11 0.349 0.00691 0.61 0.5123 0.8233 1136302 CBMicro_030154 Cc1ccc(Br)cc1S(=O)(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D17 compound treatment 0.333 -0.0126 -1.05 0.326 -0.0161 -1.43 -1.7508 -0.9886 1940669 CBMicro_030155 CSc1nncn1/N=C/c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D18 compound treatment 0.336 -0.00965 -0.8 0.331 -0.0111 -0.98 -1.2614 -0.9948 1219584 CBMicro_030156 Cc1cc(=O)cc(C)n1c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D19 compound treatment 0.329 -0.0166 -1.38 0.332 -0.0101 -0.89 -1.6097 -0.9778 1350965 CBMicro_030157 COC(=O)c1c(C)c(C)sc1NC(=O)c2sc3cc(C)ccc3c2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D20 compound treatment 0.337 -0.00865 -0.72 0.34 -0.00209 -0.19 -0.6387 -0.8616 1940670 CBMicro_030158 COC(=O)C(NC(=O)CCC1CCCCC1)C2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D21 compound treatment 0.342 -0.00365 -0.3 0.334 -0.00809 -0.72 -0.7212 -0.9264 1538527 CBMicro_030159 O=C(NCCC(c1ccccc1)c2ccccc2)c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D22 compound treatment 0.361 0.0154 1.27 0.36 0.0179 1.59 2.0235 0.9941 1581756 CBMicro_030160 OCCSC1=NS(=O)(=O)c2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D23 positive control 0.082 -0.264 -21.89 0.084 -0.258 -22.87 -31.6503 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 D24 positive control 0.085 -0.261 -21.64 0.088 -0.254 -22.52 -31.2235 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E01 mock treatment 0.335 -0.0106 -0.88 0.332 -0.0101 -0.89 -1.2574 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E02 mock treatment 0.346 3.55E-4 0.03 0.342 -9.37E-5 -0.01 0.015 0.4886 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E03 compound treatment 0.405 0.0594 4.93 0.389 0.0469 4.16 6.4237 0.9964 1526498 CBMicro_030161 Brc1ccc(cc1)C(=O)Cn2c(nc3ccccc23)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E04 compound treatment 0.342 -0.00365 -0.3 0.34 -0.00209 -0.19 -0.3452 -0.9724 1716833 CBMicro_030162 COC(=O)c1ccccc1NC(=O)C2CCC(C)(C(=O)O)C2(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E05 compound treatment 0.335 -0.0106 -0.88 0.337 -0.00509 -0.45 -0.9441 -0.9514 1592010 CBMicro_030163 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccccc3Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E06 compound treatment 0.339 -0.00665 -0.55 0.345 0.00291 0.26 -0.208 -0.3416 1671593 CBMicro_030164 COc1ccc(Cl)cc1C(=O)Nc2nc(cs2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E07 compound treatment 0.331 -0.0146 -1.22 0.321 -0.0211 -1.87 -2.1816 -0.9783 1231261 CBMicro_030165 CN(Cc1ccccc1)C(=O)COc2ccc(cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E08 compound treatment 0.347 0.00135 0.11 0.349 0.00691 0.61 0.5123 0.8233 1940671 CBMicro_030166 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)C(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E09 compound treatment 0.321 -0.0246 -2.05 0.303 -0.0391 -3.46 -3.8966 -0.9684 1267276 CBMicro_030167 Cc1ccc(cc1)S(=O)(=O)Nc2cc(C)c(O)c(c2)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E10 compound treatment 0.357 0.0114 0.94 0.337 -0.00509 -0.45 0.3474 0.3324 1940672 CBMicro_030168 CCCCOc1ccc(cc1)S(=O)(=O)n2ccnc2C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E11 compound treatment 0.33 -0.0156 -1.3 0.321 -0.0211 -1.87 -2.2403 -0.9842 1139872 CBMicro_030169 COc1ccccc1NC(=O)c2cc3c(ccc4ccccc43)oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E12 compound treatment 0.346 3.55E-4 0.03 0.348 0.00591 0.52 0.3909 0.7457 1554668 CBMicro_030170 COc1ccc(Cl)cc1C(=O)N2CCN(CC2)c3cccc(C)c3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E13 compound treatment 0.353 0.00735 0.61 0.348 0.00591 0.52 0.8019 0.9971 1726457 CBMicro_030171 CC(C)(C)c1cnnn1c2ccc(N)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E14 compound treatment 0.378 0.0324 2.69 0.367 0.0249 2.21 3.4601 0.9952 1940673 CBMicro_030172 Clc1ccc(C(=O)Nc2cccc(NC(=O)c3cccc4ccccc34)c2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E15 compound treatment 0.359 0.0134 1.11 0.346 0.00391 0.35 1.0288 0.8857 1448951 CBMicro_030173 COc1cc(C)c(Nc2ccccc2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E16 compound treatment 0.349 0.00335 0.28 0.335 -0.00709 -0.63 -0.2476 -0.3601 1422155 CBMicro_030174 O=C1C2C(C3c4ccccc4C2c5ccccc35)C(=O)N1Cc6ccco6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E17 compound treatment 0.317 -0.0286 -2.38 0.313 -0.0291 -2.58 -3.5047 -0.9992 1609140 CBMicro_030175 Cc1cc(NC2CCCCC2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E18 compound treatment 0.333 -0.0126 -1.05 0.327 -0.0151 -1.34 -1.6882 -0.9928 1634482 CBMicro_030176 CCc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E19 compound treatment 0.3 -0.0456 -3.79 0.297 -0.0451 -4.0 -5.5053 -0.9996 1940674 CBMicro_030177 CC1=CC(=NS(=O)(=O)c2ccc(C)cc2)C=C(C)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E20 compound treatment 0.352 0.00635 0.53 0.339 -0.00309 -0.27 0.1792 0.3014 1940675 CBMicro_030178 COc1ccc(OCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E21 compound treatment 0.317 -0.0286 -2.38 0.316 -0.0261 -2.31 -3.3167 -0.9999 1506669 CBMicro_030179 Nc1ccc2[nH]nc3-c4ccccc4C(=O)c1c32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E22 compound treatment 0.34 -0.00565 -0.47 0.34 -0.00209 -0.19 -0.4626 -0.9178 1505323 CBMicro_030180 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2OC)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E23 positive control 0.083 -0.263 -21.8 0.084 -0.258 -22.87 -31.5916 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 E24 positive control 0.087 -0.259 -21.47 0.09 -0.252 -22.34 -30.9808 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F01 mock treatment 0.341 -0.00465 -0.39 0.337 -0.00509 -0.45 -0.5919 -0.9969 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F02 mock treatment 0.346 3.55E-4 0.03 0.345 0.00291 0.26 0.203 0.7829 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F03 compound treatment 0.346 3.55E-4 0.03 0.34 -0.00209 -0.19 -0.1104 -0.5875 1940676 CBMicro_030181 CC(C)OC(=O)c1sc(NC(=O)c2ccc(Br)o2)c(C(=O)OC(C)C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F04 compound treatment 0.347 0.00135 0.11 0.337 -0.00509 -0.45 -0.2397 -0.5152 1782797 CBMicro_030182 [O-][N+](=O)c1cccc2C(=O)N(CCC(=O)Nc3nccs3)C(=O)c21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F05 compound treatment 0.337 -0.00865 -0.72 0.336 -0.00609 -0.54 -0.8894 -0.9902 1187534 CBMicro_030183 O=C(Nc1nncs1)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F06 compound treatment 0.341 -0.00465 -0.39 0.355 0.0129 1.14 0.5361 0.4441 1304489 CBMicro_030184 Sc1ccc(cc1)N2C(=O)c3ccc(Oc4ccc5C(=O)N(C(=O)c5c4)c6ccc(S)cc6)cc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F07 compound treatment 0.353 0.00735 0.61 0.337 -0.00509 -0.45 0.1126 0.1482 1940677 CBMicro_030185 CC(C)OC(=O)C(C)Sc1n[nH]c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F08 compound treatment 0.342 -0.00365 -0.3 0.34 -0.00209 -0.19 -0.3452 -0.9724 1940678 CBMicro_030186 Fc1ccc(cc1)c2csc(NC(=O)c3cccs3)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F09 compound treatment 0.361 0.0154 1.27 0.347 0.00491 0.43 1.2088 0.8975 1940679 CBMicro_030187 Cc1cc(C)n2c(SCc3ccc(Br)cc3)nnc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F10 compound treatment 0.313 -0.0326 -2.71 0.324 -0.0181 -1.6 -3.0502 -0.9686 1940680 CBMicro_030188 CC(C)C1=CC(=NS(=O)(=O)c2ccc(C)cc2)C=C(C(C)C)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F11 compound treatment 0.341 -0.00465 -0.39 0.34 -0.00209 -0.19 -0.4039 -0.9438 1190852 CBMicro_030189 CCOC(=O)c1sc(NC(=O)c2ccc(Cl)c(Cl)c2)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F12 compound treatment 0.4 0.0544 4.51 0.405 0.0629 5.57 7.1328 0.9945 1940681 CBMicro_030190 COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F13 compound treatment 0.354 0.00835 0.69 0.336 -0.00609 -0.54 0.1086 0.1235 1229824 CBMicro_030191 Brc1ccccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F14 compound treatment 0.346 3.55E-4 0.03 0.339 -0.00309 -0.27 -0.173 -0.6275 1368628 CBMicro_030192 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F15 compound treatment 0.328 -0.0176 -1.46 0.316 -0.0261 -2.31 -2.671 -0.9757 1456670 CBMicro_030193 CC(C)(C)SCC(O)Cn1c2ccccc2c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F16 compound treatment 0.343 -0.00265 -0.22 0.334 -0.00809 -0.72 -0.6625 -0.8831 1716335 CBMicro_030194 Clc1cccc(OCC(=O)Nc2ccc3OCCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F17 compound treatment 0.355 0.00935 0.78 0.388 0.0459 4.07 3.4259 0.8272 1685338 CBMicro_030195 COc1ccc(CSc2nnc3c4ccccc4[nH]c3n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F18 compound treatment 0.367 0.0214 1.77 0.346 0.00391 0.35 1.4984 0.8295 1940682 CBMicro_030196 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Nc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F19 compound treatment 0.395 0.0494 4.1 0.385 0.0429 3.8 5.586 0.9993 1656963 CBMicro_030197 CCC(Oc1ccccc1)C(=O)Nc2sc3CC(CCc3c2C(=O)N)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F20 compound treatment 0.346 3.55E-4 0.03 0.345 0.00291 0.26 0.203 0.7829 1439103 CBMicro_030198 COc1cc(NC(=O)COc2cccc(Cl)c2)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F21 compound treatment 0.344 -0.00165 -0.14 0.34 -0.00209 -0.19 -0.2278 -0.9886 1647725 CBMicro_030199 CCCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)sc4CC(C)CCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F22 compound treatment 0.345 -6.45E-4 -0.05 0.339 -0.00309 -0.27 -0.2317 -0.8296 1244638 CBMicro_030200 COc1cc(cc(OC)c1OC)c2nc3nnc(C)n3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F23 positive control 0.085 -0.261 -21.64 0.087 -0.255 -22.61 -31.2862 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 F24 positive control 0.084 -0.262 -21.72 0.089 -0.253 -22.43 -31.2196 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G01 mock treatment 0.336 -0.00965 -0.8 0.336 -0.00609 -0.54 -0.9481 -0.9816 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G02 mock treatment 0.339 -0.00665 -0.55 0.337 -0.00509 -0.45 -0.7093 -0.995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G03 compound treatment 0.323 -0.0226 -1.88 0.321 -0.0211 -1.87 -2.6512 -1.0 1940683 CBMicro_030201 CCOC(=O)C1C(CC(=CC1=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G04 compound treatment 0.373 0.0274 2.27 0.373 0.0309 2.74 3.5426 0.9957 1501827 CBMicro_030202 Nc1nc(c(s1)C(=O)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G05 compound treatment 0.373 0.0274 2.27 0.371 0.0289 2.56 3.4172 0.9982 1335990 CBMicro_030203 COc1ccc(C)cc1NC(=O)c2cc(Cl)ccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G06 compound treatment 0.339 -0.00665 -0.55 0.334 -0.00809 -0.72 -0.8973 -0.9916 1940684 CBMicro_030204 CCOC(=O)Nc1nc(C)c(s1)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G07 compound treatment 0.335 -0.0106 -0.88 0.337 -0.00509 -0.45 -0.9441 -0.9514 1056602 CBMicro_030205 OC(=O)c1ccccc1SCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G08 compound treatment 0.375 0.0294 2.44 0.378 0.0359 3.18 3.9733 0.9913 1525092 CBMicro_030206 Cn1ccnc1SCC(=O)c2ccc(O)c(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G09 compound treatment 0.341 -0.00465 -0.39 0.331 -0.0111 -0.98 -0.9679 -0.9165 1940685 CBMicro_030207 Cc1cc(C)n2c(SCC=C)nnc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G10 compound treatment 0.36 0.0144 1.19 0.356 0.0139 1.23 1.7141 0.9999 1289208 CBMicro_030208 Cc1onc(c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4c(Cl)cccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G11 compound treatment 0.34 -0.00565 -0.47 0.332 -0.0101 -0.89 -0.9639 -0.9545 1940686 CBMicro_030209 CN1CCN(CC1)C(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/NC(=O)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G12 compound treatment 0.429 0.0834 6.92 0.418 0.0759 6.73 9.6499 0.9999 1408358 CBMicro_030210 COc1ccc(cc1OC)c2cc(C(=O)Nc3nc(C)c(C)s3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G13 compound treatment 0.42 0.0744 6.17 0.411 0.0689 6.11 8.6829 1.0 1782093 CBMicro_030211 OC(=O)c1cccc(NC(=O)c2cc3cc(ccc3oc2=O)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G14 compound treatment 0.342 -0.00365 -0.3 0.332 -0.0101 -0.89 -0.8465 -0.8964 1940687 CBMicro_030212 CC(C)(C)c1ccc(OCC(=O)Nc2cccc(c2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G15 compound treatment 0.276 -0.0696 -5.78 0.278 -0.0641 -5.68 -8.1048 -1.0 1284746 CBMicro_030213 Cc1ccc(Nc2cc(C)c(O)c(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G16 compound treatment 0.333 -0.0126 -1.05 0.339 -0.00309 -0.27 -0.9362 -0.8628 1382751 CBMicro_030214 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3nc(cs3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G17 compound treatment 0.374 0.0284 2.35 0.378 0.0359 3.18 3.9146 0.989 1563164 CBMicro_030215 NC(=O)c1c(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3)sc4CCCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G18 compound treatment 0.329 -0.0166 -1.38 0.326 -0.0161 -1.43 -1.9856 -0.9999 1373952 CBMicro_030216 COc1ccc2C(Nc3cc(C)ccc3O)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G19 compound treatment 0.163 -0.183 -15.16 0.164 -0.178 -15.78 -21.8821 -0.9998 1709569 CBMicro_030217 COc1cc(NS(=O)(=O)c2ccc(C)cc2)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G20 compound treatment 0.348 0.00235 0.2 0.345 0.00291 0.26 0.3204 0.9907 1940688 CBMicro_030218 CC(=O)c1sc(NC(=O)c2ccoc2C)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G21 compound treatment 0.35 0.00435 0.36 0.351 0.00891 0.79 0.8138 0.9373 1940689 CBMicro_030219 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(C/C=C/c5ccccc5)CC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G22 compound treatment 0.346 3.55E-4 0.03 0.333 -0.00909 -0.81 -0.549 -0.6808 1739847 CBMicro_030220 CCOC(=O)c1c(CC)c(C)sc1NC(=O)c2cc(OC)cc(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G23 positive control 0.084 -0.262 -21.72 0.086 -0.256 -22.7 -31.4076 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 G24 positive control 0.088 -0.258 -21.39 0.093 -0.249 -22.08 -30.7341 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H01 mock treatment 0.335 -0.0106 -0.88 0.336 -0.00609 -0.54 -1.0068 -0.9721 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H02 mock treatment 0.345 -6.45E-4 -0.05 0.334 -0.00809 -0.72 -0.5451 -0.7578 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H03 compound treatment 0.345 -6.45E-4 -0.05 0.342 -9.37E-5 -0.01 -0.0437 -0.8071 1940690 CBMicro_030221 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)o2)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H04 compound treatment 0.344 -0.00165 -0.14 0.338 -0.00409 -0.36 -0.3531 -0.9109 1940691 CBMicro_030222 COc1ccc(cc1)C(=O)CSc2nnc(c3ccc(Br)cc3)n2CC(=C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H05 compound treatment 0.387 0.0414 3.43 0.394 0.0519 4.6 5.6804 0.9896 1940692 CBMicro_030223 [O-][N+](=O)c1cc(Cl)ccc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H06 compound treatment 0.364 0.0184 1.52 0.358 0.0159 1.41 2.0743 0.9992 1940693 CBMicro_030224 CCOc1ccccc1NC(=O)COc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H07 compound treatment 0.367 0.0214 1.77 0.359 0.0169 1.5 2.313 0.9965 1253838 CBMicro_030225 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(N3C(=O)c4ccc(Cl)cc4C3=O)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H08 compound treatment 0.334 -0.0116 -0.97 0.338 -0.00409 -0.36 -0.9401 -0.9105 1132516 CBMicro_030226 COc1cc(Br)c(Nc2nc(cs2)c3cccnc3)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H09 compound treatment 0.451 0.105 8.75 0.474 0.132 11.69 14.4506 0.9898 1940694 CBMicro_030227 CCOc1cc(cc(OCC)c1OCC)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H10 compound treatment 0.35 0.00435 0.36 0.343 9.06E-4 0.08 0.3124 0.8436 1216420 CBMicro_030228 COc1ccc(cc1)C(=O)Oc2ccc3c4CCCc4c(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H11 compound treatment 0.351 0.00535 0.44 0.347 0.00491 0.43 0.6218 0.9999 1411256 CBMicro_030229 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(Br)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H12 compound treatment 0.557 0.211 17.55 0.519 0.177 15.68 23.4931 0.9984 1784111 CBMicro_030230 NS(=O)(=O)c1ccc(cc1)N2N=C(CC2c3ccc(F)cc3)/C=C/c4ccc(F)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H13 compound treatment 0.339 -0.00665 -0.55 0.359 0.0169 1.5 0.6693 0.4192 1227616 CBMicro_030231 CCN(CC)C(=O)c1sc(NC(=O)c2ccc(C)c(C)c2)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H14 compound treatment 0.34 -0.00565 -0.47 0.335 -0.00709 -0.63 -0.7759 -0.9895 1940695 CBMicro_030232 COc1ccc(cc1)C2=NN(CN3C(=O)C(=O)c4cc(Br)ccc34)C(C2)c5cccc(c5)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H15 compound treatment 0.335 -0.0106 -0.88 0.346 0.00391 0.35 -0.3801 -0.4005 1940696 CBMicro_030233 CC(C)(C)c1cc(CCC(=O)NNC(=O)c2ccccc2)cc(c1O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H16 compound treatment 0.353 0.00735 0.61 0.352 0.00991 0.88 1.0525 0.9843 1665657 CBMicro_030234 COc1ccc(cc1)C(=O)NCC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H17 compound treatment 0.332 -0.0136 -1.13 0.332 -0.0101 -0.89 -1.4335 -0.9932 1161161 CBMicro_030235 CN(C)c1ccc(cc1)C(C2=C(O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H18 compound treatment 0.336 -0.00965 -0.8 0.332 -0.0101 -0.89 -1.1987 -0.9985 1940697 CBMicro_030236 CSc1nnc2sc3ccccc3n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H19 compound treatment 0.36 0.0144 1.19 0.358 0.0159 1.41 1.8394 0.9965 1157472 CBMicro_030237 COc1cccc(NC(=O)c2sc3ccccc3c2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H20 compound treatment 0.331 -0.0146 -1.22 0.336 -0.00609 -0.54 -1.2416 -0.9333 1123542 CBMicro_030238 CC(C)c1ccccc1NC(=O)C(C)N2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H21 compound treatment 0.349 0.00335 0.28 0.333 -0.00909 -0.81 -0.3729 -0.4374 1503054 CBMicro_030239 O=C(Nc1ccc(Oc2ccccc2)cc1)c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H22 compound treatment 0.336 -0.00965 -0.8 0.331 -0.0111 -0.98 -1.2614 -0.9948 1291451 CBMicro_030240 CCOc1ccc2nc(SCC(=O)Nc3cc(Cl)ccc3C)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H23 positive control 0.086 -0.26 -21.56 0.086 -0.256 -22.7 -31.2902 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 H24 positive control 0.091 -0.255 -21.14 0.092 -0.25 -22.16 -30.6207 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I01 mock treatment 0.348 0.00235 0.2 0.345 0.00291 0.26 0.3204 0.9907 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I02 mock treatment 0.364 0.0184 1.52 0.346 0.00391 0.35 1.3223 0.8462 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I03 compound treatment 0.342 -0.00365 -0.3 0.334 -0.00809 -0.72 -0.7212 -0.9264 1589894 CBMicro_030241 Oc1ccc(cc1O)c2cn3CCSc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I04 compound treatment 0.346 3.55E-4 0.03 0.336 -0.00609 -0.54 -0.361 -0.6675 1940698 CBMicro_030242 CC1=C(C(N2C(=O)CSC2=N1)c3ccc(cc3)[N+](=O)[O-])C(=O)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I05 compound treatment 0.354 0.00835 0.69 0.347 0.00491 0.43 0.7979 0.9747 1727416 CBMicro_030243 COC(=O)c1sccc1NC(=O)c2cccc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I06 compound treatment 0.341 -0.00465 -0.39 0.334 -0.00809 -0.72 -0.7799 -0.9576 1689138 CBMicro_030244 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(NC(=O)C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I07 compound treatment 0.364 0.0184 1.52 0.335 -0.00709 -0.63 0.633 0.384 1940699 CBMicro_030245 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I08 compound treatment 0.381 0.0354 2.94 0.352 0.00991 0.88 2.6962 0.8801 1940700 CBMicro_030246 CCOC(=O)C1C(CC(=CC1=O)c2ccc(OC)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I09 compound treatment 0.335 -0.0106 -0.88 0.352 0.00991 0.88 -0.0041 -0.0033 1491135 CBMicro_030247 CC(=O)N1N=C(C)CC1(O)c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I10 compound treatment 0.369 0.0234 1.94 0.374 0.0319 2.83 3.3704 0.9831 1940701 CBMicro_030248 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccc(F)c(c3)[N+](=O)[O-])c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I11 compound treatment 0.352 0.00635 0.53 0.348 0.00591 0.52 0.7432 1.0 1940702 CBMicro_030249 CC(=O)c1ccc(NC(=O)c2cc3c(ccc4ccccc43)oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I12 compound treatment 0.345 -6.45E-4 -0.05 0.377 0.0349 3.09 2.1495 0.6948 1162238 CBMicro_030250 Cc1onc(c1C(=O)N2CCN(CC2)c3cccc(C)c3C)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I13 compound treatment 0.364 0.0184 1.52 0.349 0.00691 0.61 1.5103 0.9197 1940703 CBMicro_030251 Oc1ccccc1NC(=O)CSc2nnnn2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I14 compound treatment 0.36 0.0144 1.19 0.36 0.0179 1.59 1.9648 0.99 1346320 CBMicro_030252 COc1cc(cc(OC)c1OC)C(=O)c2cc(Br)ccc2NC(=O)COc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I15 compound treatment 0.367 0.0214 1.77 0.363 0.0209 1.85 2.5637 0.9998 1397942 CBMicro_030253 Cc1cc(=O)oc2cc(OC(=O)C(c3ccccc3)c4ccccc4)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I16 compound treatment 0.361 0.0154 1.27 0.356 0.0139 1.23 1.7728 0.9999 1527325 CBMicro_030254 Clc1ccc(NC(=O)c2ccco2)c(c1)C(=O)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I17 compound treatment 0.345 -6.45E-4 -0.05 0.351 0.00891 0.79 0.5202 0.6576 1940704 CBMicro_030255 CCOC(=O)c1c(NC(=O)CN2C(=O)c3cccc4cccc(C2=O)c34)sc5CCCCc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I18 compound treatment 0.349 0.00335 0.28 0.358 0.0159 1.41 1.1937 0.8308 1288555 CBMicro_030256 COc1ccc(OC)c(NC(=O)c2cc3ccccc3o2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I19 compound treatment 0.342 -0.00365 -0.3 0.337 -0.00509 -0.45 -0.5332 -0.9811 1495861 CBMicro_030257 COc1cccc(NC(=O)C2COc3ccccc3O2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I20 compound treatment 0.349 0.00335 0.28 0.353 0.0109 0.97 0.8804 0.8753 1279684 CBMicro_030258 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I21 compound treatment 0.346 3.55E-4 0.03 0.351 0.00891 0.79 0.5789 0.733 1940705 CBMicro_030259 COc1ccc(cc1[N+](=O)[O-])S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I22 compound treatment 0.347 0.00135 0.11 0.346 0.00391 0.35 0.3243 0.891 1216380 CBMicro_030260 NC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)c(Cl)c4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I23 positive control 0.084 -0.262 -21.72 0.088 -0.254 -22.52 -31.2822 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 I24 positive control 0.089 -0.257 -21.31 0.092 -0.25 -22.16 -30.7381 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J01 mock treatment 0.325 -0.0206 -1.71 0.341 -0.00109 -0.1 -1.2805 -0.7459 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J02 mock treatment 0.349 0.00335 0.28 0.352 0.00991 0.88 0.8177 0.8878 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J03 compound treatment 0.339 -0.00665 -0.55 0.329 -0.0131 -1.16 -1.2106 -0.9422 1127525 CBMicro_030261 COC(=O)c1sc(NC(=O)c2ccccc2F)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J04 compound treatment 0.349 0.00335 0.28 0.339 -0.00309 -0.27 0.0031 0.0079 1940706 CBMicro_030262 ON1C(Nc2ccccc2C1=O)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J05 compound treatment 0.363 0.0174 1.44 0.363 0.0209 1.85 2.3289 0.9923 1399491 CBMicro_030263 Cc1cccnc1NC(=O)c2cc(nc3ccccc23)c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J06 compound treatment 0.353 0.00735 0.61 0.341 -0.00109 -0.1 0.3632 0.5875 1940707 CBMicro_030264 COc1ccc(/C=C/C(=O)NCC=C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J07 compound treatment 0.352 0.00635 0.53 0.345 0.00291 0.26 0.5552 0.9456 1940708 CBMicro_030265 COCCOC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J08 compound treatment 0.343 -0.00265 -0.22 0.33 -0.0121 -1.07 -0.9131 -0.8346 1121474 CBMicro_030266 COc1cc(OC)cc(c1)C(=O)Nc2ccc(C)cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J09 compound treatment 0.358 0.0124 1.03 0.353 0.0109 0.97 1.4087 0.9996 1940709 CBMicro_030267 COc1ccc(NC(=O)c2sc3cc(C)ccc3c2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J10 compound treatment 0.343 -0.00265 -0.22 0.342 -9.37E-5 -0.01 -0.1612 -0.7333 1462835 CBMicro_030268 COC(=O)CC1(NC(=O)C(=C1C(=O)OC)N)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J11 compound treatment 0.333 -0.0126 -1.05 0.335 -0.00709 -0.63 -1.1868 -0.9699 1940710 CBMicro_030269 COc1ccc(CSc2nc3ccccc3o2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J12 compound treatment 0.354 0.00835 0.69 0.336 -0.00609 -0.54 0.1086 0.1235 1161800 CBMicro_030270 Nc1ccc(cc1)c2cn3ccsc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J13 compound treatment 0.345 -6.45E-4 -0.05 0.343 9.06E-4 0.08 0.0189 0.196 1940711 CBMicro_030271 COCCOC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J14 compound treatment 0.376 0.0304 2.52 0.345 0.00291 0.26 1.964 0.7753 1582019 CBMicro_030272 COc1cc(NC(=O)COc2ccc(C)c(C)c2)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J15 compound treatment 0.351 0.00535 0.44 0.34 -0.00209 -0.19 0.1831 0.3802 1404109 CBMicro_030273 COc1ccccc1C(=O)Nc2ccc(F)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J16 compound treatment 0.348 0.00235 0.2 0.345 0.00291 0.26 0.3204 0.9907 1484216 CBMicro_030274 Brc1ccc(OCC(=O)NCC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J17 compound treatment 0.353 0.00735 0.61 0.346 0.00391 0.35 0.6765 0.9639 1940712 CBMicro_030275 O=C(Nc1ccc(cc1)N2CCOCC2)/C=C/c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J18 compound treatment 0.378 0.0324 2.69 0.38 0.0379 3.36 4.2747 0.9939 1262888 CBMicro_030276 CN(C)c1ccc(NC(=O)COc2c(C)cccc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J19 compound treatment 0.344 -0.00165 -0.14 0.35 0.00791 0.7 0.3989 0.5588 1614106 CBMicro_030277 COc1cc(OC)cc(c1)C(=O)NC2CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J20 compound treatment 0.343 -0.00265 -0.22 0.344 0.00191 0.17 -0.0358 -0.1293 1387522 CBMicro_030278 OC(=O)c1c2CCCCCc2nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J21 compound treatment 0.412 0.0664 5.51 0.4 0.0579 5.13 7.5239 0.9994 1421235 CBMicro_030279 COc1ccc2C(CC(=O)c3ccc(cc3)N(C)C)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J22 compound treatment 0.384 0.0384 3.18 0.355 0.0129 1.14 3.0603 0.9045 1940713 CBMicro_030280 O=C(c1ccccc1)c2cccc(NC3=NS(=O)(=O)c4ccccc34)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J23 positive control 0.084 -0.262 -21.72 0.087 -0.255 -22.61 -31.3449 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 J24 positive control 0.088 -0.258 -21.39 0.093 -0.249 -22.08 -30.7341 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K01 mock treatment 0.339 -0.00665 -0.55 0.344 0.00191 0.17 -0.2706 -0.4691 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K02 mock treatment 0.346 3.55E-4 0.03 0.344 0.00191 0.17 0.1403 0.8181 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K03 compound treatment 0.341 -0.00465 -0.39 0.333 -0.00909 -0.81 -0.8425 -0.9431 1940714 CBMicro_030281 CC(C)(C)c1nnc(NC(=O)CSc2nnnn2c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K04 compound treatment 0.35 0.00435 0.36 0.343 9.06E-4 0.08 0.3124 0.8436 1940715 CBMicro_030282 COc1ccc(cc1)C2=NN(C(C2)c3ccc(cc3)[N+](=O)[O-])C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K05 compound treatment 0.366 0.0204 1.69 0.362 0.0199 1.76 2.4423 0.9998 1940716 CBMicro_030283 CC(=O)c1sc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K06 compound treatment 0.332 -0.0136 -1.13 0.329 -0.0131 -1.16 -1.6215 -0.9999 1940717 CBMicro_030284 COc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K07 compound treatment 0.336 -0.00965 -0.8 0.326 -0.0161 -1.43 -1.5747 -0.9627 1433952 CBMicro_030285 Cc1ccc(cc1)S(=O)(=O)Nc2cc(C)c(O)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K08 compound treatment 0.331 -0.0146 -1.22 0.325 -0.0171 -1.51 -1.9309 -0.9941 1587192 CBMicro_030286 C=CCn1c(n[nH]c1=S)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K09 compound treatment 0.348 0.00235 0.2 0.346 0.00391 0.35 0.383 0.9634 1940718 CBMicro_030287 COc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K10 compound treatment 0.34 -0.00565 -0.47 0.336 -0.00609 -0.54 -0.7133 -0.9975 1551602 CBMicro_030288 CCc1nnc(NC(=O)C2CCCO2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K11 compound treatment 0.381 0.0354 2.94 0.392 0.0499 4.42 5.2028 0.9802 1408506 CBMicro_030289 Cc1cc(C)nc(SCC(=O)N2c3ccccc3Sc4ccc(Cl)cc24)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K12 compound treatment 0.411 0.0654 5.43 0.43 0.0879 7.79 9.3452 0.9844 1473696 CBMicro_030290 Cc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K13 compound treatment 0.414 0.0684 5.67 0.415 0.0729 6.46 8.5813 0.9979 1940719 CBMicro_030291 COc1ccc(/C=C/C(=O)Nc2ccc(Br)cc2C(=O)c3cc(OC)c(OC)c(OC)c3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K14 compound treatment 0.337 -0.00865 -0.72 0.335 -0.00709 -0.63 -0.952 -0.9978 1324829 CBMicro_030292 CC1(C)C(CCC1(C)C(=O)O)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K15 compound treatment 0.356 0.0104 0.86 0.362 0.0199 1.76 1.8553 0.9454 1940720 CBMicro_030293 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(C)cc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K16 compound treatment 0.324 -0.0216 -1.8 0.316 -0.0261 -2.31 -2.9058 -0.9922 1587992 CBMicro_030294 Cc1ccc(NC2c3ccccc3Oc4ccccc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K17 compound treatment 0.352 0.00635 0.53 0.347 0.00491 0.43 0.6805 0.9954 1439944 CBMicro_030295 CCOc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K18 compound treatment 0.342 -0.00365 -0.3 0.347 0.00491 0.43 0.0935 0.1764 1580108 CBMicro_030296 Fc1ccccc1NC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K19 compound treatment 0.409 0.0634 5.26 0.414 0.0719 6.37 8.2252 0.9955 1940721 CBMicro_030297 Cn1c(=O)c([N+](=O)[O-])c(NCCCO)c2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K20 compound treatment 0.339 -0.00665 -0.55 0.338 -0.00409 -0.36 -0.6466 -0.9793 1673546 CBMicro_030298 O=C(Nc1nc2ccccc2[nH]1)C3CCCO3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K21 compound treatment 0.365 0.0194 1.61 0.372 0.0299 2.65 3.0103 0.9712 1940722 CBMicro_030299 Cn1c(=O)c([N+](=O)[O-])c(N2CCN(CC2)C(=O)c3ccccc3)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K22 compound treatment 0.344 -0.00165 -0.14 0.339 -0.00309 -0.27 -0.2904 -0.9482 1646146 CBMicro_030300 COc1ccc(OC)c(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K23 positive control 0.083 -0.263 -21.8 0.086 -0.256 -22.7 -31.4663 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 K24 positive control 0.088 -0.258 -21.39 0.096 -0.246 -21.81 -30.5461 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L01 mock treatment 0.343 -0.00265 -0.22 0.343 9.06E-4 0.08 -0.0985 -0.4212 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L02 mock treatment 0.346 3.55E-4 0.03 0.342 -9.37E-5 -0.01 0.015 0.4886 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L03 compound treatment 0.348 0.00235 0.2 0.342 -9.37E-5 -0.01 0.1324 0.6764 1685291 CBMicro_030301 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L04 compound treatment 0.336 -0.00965 -0.8 0.33 -0.0121 -1.07 -1.3241 -0.9897 1940723 CBMicro_030302 CN(/C(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2)c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L05 compound treatment 0.356 0.0104 0.86 0.363 0.0209 1.85 1.918 0.939 1940724 CBMicro_030303 Cc1ccc(c2csc(NC(=O)c3ccc(Cl)cc3[N+](=O)[O-])n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L06 compound treatment 0.339 -0.00665 -0.55 0.336 -0.00609 -0.54 -0.772 -0.9999 1940725 CBMicro_030304 CC1CCN(CC1)S(=O)(=O)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L07 compound treatment 0.364 0.0184 1.52 0.342 -9.37E-5 -0.01 1.0716 0.7032 1940726 CBMicro_030305 Cc1cc(NC(=O)c2ccc(cc2)[N+](=O)[O-])ccc1c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L08 compound treatment 0.344 -0.00165 -0.14 0.334 -0.00809 -0.72 -0.6038 -0.8269 1637374 CBMicro_030306 Cc1cccc(C)c1OCC(=O)Nc2sc3CCCc3c2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L09 compound treatment 0.348 0.00235 0.2 0.342 -9.37E-5 -0.01 0.1324 0.6764 1119722 CBMicro_030307 CN(C)c1ccc(NC(=O)c2cccnc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L10 compound treatment 0.335 -0.0106 -0.88 0.333 -0.00909 -0.81 -1.1948 -0.9989 1196232 CBMicro_030308 Cc1cccc(C)c1OCC(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L11 compound treatment 0.349 0.00335 0.28 0.338 -0.00409 -0.36 -0.0596 -0.1303 1940727 CBMicro_030309 Cc1sc2nc(NC(=O)c3ccccc3)sc(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L12 compound treatment 0.331 -0.0146 -1.22 0.33 -0.0121 -1.07 -1.6176 -0.998 1493753 CBMicro_030310 CC(C)c1ccc(cc1)C2NC(=S)NC(=C2C(=O)Nc3ccccc3Cl)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L13 compound treatment 0.341 -0.00465 -0.39 0.333 -0.00909 -0.81 -0.8425 -0.9431 1940728 CBMicro_030311 COCCOC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L14 compound treatment 0.334 -0.0116 -0.97 0.325 -0.0171 -1.51 -1.7548 -0.9765 1272761 CBMicro_030312 COC(=O)c1cccc(NC(=O)CCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L15 compound treatment 0.35 0.00435 0.36 0.352 0.00991 0.88 0.8764 0.9231 1940729 CBMicro_030313 COc1ccc(/C=N\N2CCN(CC2)c3ccc(Cl)cc3)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L16 compound treatment 0.332 -0.0136 -1.13 0.327 -0.0151 -1.34 -1.7469 -0.9966 1187280 CBMicro_030314 Cc1cc(OCC(=O)Nc2ccc(F)cc2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L17 compound treatment 0.328 -0.0176 -1.46 0.333 -0.00909 -0.81 -1.6057 -0.9604 1940730 CBMicro_030315 O=C(Nc1ccc2OCCOc2c1)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L18 compound treatment 0.415 0.0694 5.76 0.411 0.0689 6.11 8.3894 0.9996 1940731 CBMicro_030316 COc1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L19 compound treatment 0.34 -0.00565 -0.47 0.347 0.00491 0.43 -0.0239 -0.0374 1195108 CBMicro_030317 CC(=C)Cn1c(SCC(=O)O)nnc1c2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L20 compound treatment 0.335 -0.0106 -0.88 0.341 -0.00109 -0.1 -0.6934 -0.78 1940732 CBMicro_030318 Cc1ccc(NC(=O)C(=O)NCCOC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L21 compound treatment 0.361 0.0154 1.27 0.353 0.0109 0.97 1.5848 0.9907 1777870 CBMicro_030319 COc1ccc2C(Nc3cccc(c3)[N+](=O)[O-])OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L22 compound treatment 0.342 -0.00365 -0.3 0.344 0.00191 0.17 -0.0945 -0.2727 1149641 CBMicro_030320 Brc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L23 positive control 0.085 -0.261 -21.64 0.087 -0.255 -22.61 -31.2862 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 L24 positive control 0.088 -0.258 -21.39 0.093 -0.249 -22.08 -30.7341 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M01 mock treatment 0.345 -6.45E-4 -0.05 0.341 -0.00109 -0.1 -0.1064 -0.9609 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M02 mock treatment 0.344 -0.00165 -0.14 0.34 -0.00209 -0.19 -0.2278 -0.9886 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M03 compound treatment 0.343 -0.00265 -0.22 0.336 -0.00609 -0.54 -0.5371 -0.9214 1940733 CBMicro_030321 CCOC(=O)c1sc(NC(=O)c2cccc3ccccc23)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M04 compound treatment 0.342 -0.00365 -0.3 0.336 -0.00609 -0.54 -0.5958 -0.9625 1625075 CBMicro_030322 CC(Oc1cccc(Cl)c1)C(=O)Nc2cccc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M05 compound treatment 0.327 -0.0186 -1.55 0.331 -0.0111 -0.98 -1.7897 -0.976 1738829 CBMicro_030323 Cc1sc(NC(=O)c2ccc(C)cc2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M06 compound treatment 0.341 -0.00465 -0.39 0.341 -0.00109 -0.1 -0.3412 -0.8581 1940734 CBMicro_030324 Cc1sc(NC(=O)c2cccc(Br)c2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M07 compound treatment 0.342 -0.00365 -0.3 0.32 -0.0221 -1.96 -1.5985 -0.8068 1940735 CBMicro_030325 CN(C)C1=C/C(=N/S(=O)(=O)c2ccccc2)/c3ccccc3C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M08 compound treatment 0.336 -0.00965 -0.8 0.332 -0.0101 -0.89 -1.1987 -0.9985 1555280 CBMicro_030326 CCc1nccn1S(=O)(=O)c2cc(Cl)ccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M09 compound treatment 0.333 -0.0126 -1.05 0.332 -0.0101 -0.89 -1.3748 -0.9968 1486172 CBMicro_030327 C(Sc1nnnn1c2ccccc2)c3cccc(Oc4ccccc4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M10 compound treatment 0.379 0.0334 2.77 0.375 0.0329 2.92 4.0201 0.9997 1523066 CBMicro_030328 COc1ccc(c(OC)c1)c2cc(C(=O)Nc3ccccc3F)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M11 compound treatment 0.331 -0.0146 -1.22 0.34 -0.00209 -0.19 -0.9909 -0.8057 1144845 CBMicro_030329 Cn1ccnc1SCC(=O)c2ccc(cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M12 compound treatment 0.354 0.00835 0.69 0.361 0.0189 1.68 1.6752 0.9238 1427046 CBMicro_030330 COc1ccc(Cl)cc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M13 compound treatment 0.368 0.0224 1.86 0.394 0.0519 4.6 4.565 0.9203 1940736 CBMicro_030331 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Br)cc2C(=O)c3cc(OC)c(OC)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M14 compound treatment 0.342 -0.00365 -0.3 0.339 -0.00309 -0.27 -0.4079 -0.9988 1940737 CBMicro_030332 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(Br)cc2C(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M15 compound treatment 0.336 -0.00965 -0.8 0.338 -0.00409 -0.36 -0.8227 -0.9359 1248192 CBMicro_030333 Cc1cc(O)c(cc1C)C(=O)c2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M16 compound treatment 0.33 -0.0156 -1.3 0.335 -0.00709 -0.63 -1.363 -0.9445 1940738 CBMicro_030334 OC(=O)c1ccc(NS(=O)(=O)c2cc(ccc2Br)C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M17 compound treatment 0.339 -0.00665 -0.55 0.335 -0.00709 -0.63 -0.8346 -0.9979 1687344 CBMicro_030335 CCCOC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M18 compound treatment 0.338 -0.00765 -0.63 0.334 -0.00809 -0.72 -0.956 -0.9981 1940739 CBMicro_030336 CCN(CC)c1ccc(/C=N\N2CCN(CC2)c3ccc(Cl)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M19 compound treatment 0.368 0.0224 1.86 0.367 0.0249 2.21 2.8731 0.9963 1940740 CBMicro_030337 Cn1c(=O)c([N+](=O)[O-])c(N2CCN(CC2)c3ccccn3)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M20 compound treatment 0.332 -0.0136 -1.13 0.335 -0.00709 -0.63 -1.2455 -0.9614 1340847 CBMicro_030338 COc1ccc(cc1)C(=O)Nc2nc(C)cs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M21 compound treatment 0.377 0.0314 2.6 0.374 0.0319 2.83 3.84 0.9991 1940741 CBMicro_030339 CCCCNc1c([N+](=O)[O-])c(=O)n(C)c2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M22 compound treatment 0.374 0.0284 2.35 0.358 0.0159 1.41 2.6613 0.9699 1940742 CBMicro_030340 CCOC(=O)c1sc(NC(=O)c2ccc(Br)o2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M23 positive control 0.084 -0.262 -21.72 0.088 -0.254 -22.52 -31.2822 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 M24 positive control 0.088 -0.258 -21.39 0.094 -0.248 -21.99 -30.6714 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N01 mock treatment 0.355 0.00935 0.78 0.345 0.00291 0.26 0.7313 0.8937 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N02 mock treatment 0.348 0.00235 0.2 0.348 0.00591 0.52 0.5084 0.9098 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N03 compound treatment 0.354 0.00835 0.69 0.35 0.00791 0.7 0.9859 1.0 1940743 CBMicro_030341 Clc1ccc(cc1)C(=O)Nc2nc(cs2)c3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N04 compound treatment 0.353 0.00735 0.61 0.343 9.06E-4 0.08 0.4885 0.7933 1397248 CBMicro_030342 CCOc1ccc(cc1)N2C(=O)CC(Nc3ccc(cc3)N4CCOCC4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N05 compound treatment 0.346 3.55E-4 0.03 0.344 0.00191 0.17 0.1403 0.8181 1266909 CBMicro_030343 CCc1nnc(NC(=O)c2ccc(OC)cc2OC)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N06 compound treatment 0.349 0.00335 0.28 0.345 0.00291 0.26 0.3791 0.9992 1940744 CBMicro_030344 ON(C(=O)c1ccco1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N07 compound treatment 0.341 -0.00465 -0.39 0.336 -0.00609 -0.54 -0.6546 -0.9864 1217815 CBMicro_030345 COc1ccc(OCC(=O)Nc2ccc(F)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N08 compound treatment 0.351 0.00535 0.44 0.348 0.00591 0.52 0.6845 0.9967 1260672 CBMicro_030346 CCOC(=O)Cc1csc(NC(=O)COc2c(C)cccc2C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N09 compound treatment 0.339 -0.00665 -0.55 0.325 -0.0171 -1.51 -1.4613 -0.9064 1240523 CBMicro_030347 CC(C)(C)c1ccc(OCC(=O)Nc2nccs2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N10 compound treatment 0.341 -0.00465 -0.39 0.342 -9.37E-5 -0.01 -0.2786 -0.7222 1940745 CBMicro_030348 COc1ccc(CSc2nc(C)cc(O)n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N11 compound treatment 0.367 0.0214 1.77 0.354 0.0119 1.06 1.9997 0.9693 1940746 CBMicro_030349 CSc1nncn1/N=C/c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N12 compound treatment 0.381 0.0354 2.94 0.379 0.0369 3.27 4.3882 0.9985 1940747 CBMicro_030350 CCOC(=O)c1sc(NC(=O)c2ccc(s2)[N+](=O)[O-])nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N13 compound treatment 0.345 -6.45E-4 -0.05 0.346 0.00391 0.35 0.2069 0.5907 1940748 CBMicro_030351 Clc1ccc(NC(=O)CC2SC(=N)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N14 compound treatment 0.368 0.0224 1.86 0.358 0.0159 1.41 2.3091 0.9908 1940749 CBMicro_030352 COc1cc(ccc1NC(=O)COc2ccccc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N15 compound treatment 0.344 -0.00165 -0.14 0.335 -0.00709 -0.63 -0.5411 -0.8411 1940750 CBMicro_030353 Brc1ccccc1/C=N\NC(=O)c2cnccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N16 compound treatment 0.377 0.0314 2.6 0.38 0.0379 3.36 4.216 0.9921 1940751 CBMicro_030354 Clc1ccc(NC(=O)Nc2nnc(s2)C(c3ccccc3)c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N17 compound treatment 0.351 0.00535 0.44 0.349 0.00691 0.61 0.7471 0.9877 1940752 CBMicro_030355 CC(C)(C)c1cnnn1c2ccc(/C=C/C(=O)c3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N18 compound treatment 0.333 -0.0126 -1.05 0.332 -0.0101 -0.89 -1.3748 -0.9968 1354196 CBMicro_030356 CC(C)c1cc(NS(=O)(=O)c2ccccc2N)cc(C(C)C)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N19 compound treatment 0.341 -0.00465 -0.39 0.336 -0.00609 -0.54 -0.6546 -0.9864 1371467 CBMicro_030357 CCOC(=O)c1ccc2[nH]cc(C(=O)OCC)c(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N20 compound treatment 0.376 0.0304 2.52 0.377 0.0349 3.09 3.9693 0.9948 1940753 CBMicro_030358 OC(CNC(=O)C(=O)Nc1ccccc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N21 compound treatment 0.347 0.00135 0.11 0.351 0.00891 0.79 0.6376 0.7998 1940754 CBMicro_030359 CC(=O)N(c1nnc(C)s1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N22 compound treatment 0.356 0.0104 0.86 0.346 0.00391 0.35 0.8526 0.9201 1940755 CBMicro_030360 CC(=O)Nc1ccc(cc1)C2=N/C(=C/c3ccc(Br)cc3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N23 positive control 0.085 -0.261 -21.64 0.09 -0.252 -22.34 -31.0982 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 N24 positive control 0.089 -0.257 -21.31 0.093 -0.249 -22.08 -30.6754 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O01 mock treatment 0.348 0.00235 0.2 0.346 0.00391 0.35 0.383 0.9634 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O02 mock treatment 0.346 3.55E-4 0.03 0.346 0.00391 0.35 0.2656 0.7645 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O03 compound treatment 0.341 -0.00465 -0.39 0.339 -0.00309 -0.27 -0.4666 -0.986 1445916 CBMicro_030361 CCOC(=O)c1sc(NC(=O)CC(c2ccccc2)c3ccccc3)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O04 compound treatment 0.351 0.00535 0.44 0.348 0.00591 0.52 0.6845 0.9967 1242908 CBMicro_030362 COc1cccc(c1)c2cc(C(=O)Nc3nnn[nH]3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O05 compound treatment 0.356 0.0104 0.86 0.36 0.0179 1.59 1.73 0.9585 1163144 CBMicro_030363 Cc1sc(NC(=O)Cc2ccccc2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O06 compound treatment 0.348 0.00235 0.2 0.352 0.00991 0.88 0.759 0.8439 1940756 CBMicro_030364 COc1ccc(NC(=O)/C=C/c2ccc(C)o2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O07 compound treatment 0.413 0.0674 5.59 0.401 0.0589 5.22 7.6453 0.9994 1581792 CBMicro_030365 CC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O08 compound treatment 0.336 -0.00965 -0.8 0.342 -9.37E-5 -0.01 -0.5721 -0.7144 1625251 CBMicro_030366 COc1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O09 compound treatment 0.381 0.0354 2.94 0.381 0.0389 3.45 4.5135 0.9968 1940757 CBMicro_030367 CCOc1cc(ccc1NC(=O)C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O10 compound treatment 0.34 -0.00565 -0.47 0.34 -0.00209 -0.19 -0.4626 -0.9178 1196105 CBMicro_030368 Cc1occc1C(=O)NCC2CCCO2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O11 compound treatment 0.351 0.00535 0.44 0.349 0.00691 0.61 0.7471 0.9877 1940758 CBMicro_030369 Cc1cc(O)nc(SCC(=O)Nc2ccccc2Br)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O12 compound treatment 0.35 0.00435 0.36 0.347 0.00491 0.43 0.5631 0.9958 1080225 CBMicro_030370 COc1ccc(CCNC(=O)c2ccc(Cl)c(Cl)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O13 compound treatment 0.343 -0.00265 -0.22 0.343 9.06E-4 0.08 -0.0985 -0.4212 1467811 CBMicro_030371 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O14 compound treatment 0.352 0.00635 0.53 0.35 0.00791 0.7 0.8685 0.9902 1542102 CBMicro_030372 Clc1ccc2nc(Nc3cccc(c3)C(=O)N4CCOCC4)nc(c5ccccc5)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O15 compound treatment 0.358 0.0124 1.03 0.362 0.0199 1.76 1.9727 0.9667 1322119 CBMicro_030373 O=c1oc2cc(OCC#C)ccc2c3CCCc31 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O16 compound treatment 0.393 0.0474 3.93 0.386 0.0439 3.89 5.5313 1.0 1603826 CBMicro_030374 COc1ccc(cc1)c2cc(C(=O)Nc3ccccn3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O17 compound treatment 0.333 -0.0126 -1.05 0.331 -0.0111 -0.98 -1.4375 -0.9995 1184105 CBMicro_030375 Cc1ccc(cc1)S(=O)(=O)c2cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc4c2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O18 compound treatment 0.344 -0.00165 -0.14 0.349 0.00691 0.61 0.3362 0.5361 1176597 CBMicro_030376 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ncccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O19 compound treatment 0.413 0.0674 5.59 0.406 0.0639 5.66 7.9586 1.0 1940759 CBMicro_030377 Cn1c(=O)c([N+](=O)[O-])c(NCCO)c2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O20 compound treatment 0.345 -6.45E-4 -0.05 0.352 0.00991 0.88 0.5829 0.6627 1241370 CBMicro_030378 COc1cccc(c1)c2cc(C(=O)Nc3ncccn3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O21 compound treatment 0.345 -6.45E-4 -0.05 0.347 0.00491 0.43 0.2696 0.6154 1279391 CBMicro_030379 CC1(C)CC(CC(=O)O)(Cc2ccccc2)CCO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O22 compound treatment 0.355 0.00935 0.78 0.353 0.0109 0.97 1.2326 0.9941 1706850 CBMicro_030380 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(F)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O23 positive control 0.085 -0.261 -21.64 0.088 -0.254 -22.52 -31.2235 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 O24 positive control 0.09 -0.256 -21.22 0.092 -0.25 -22.16 -30.6794 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P01 mock treatment 0.35 0.00435 0.36 0.34 -0.00209 -0.19 0.1244 0.3062 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P02 mock treatment 0.352 0.00635 0.53 0.344 0.00191 0.17 0.4925 0.8891 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P03 compound treatment 0.358 0.0124 1.03 0.339 -0.00309 -0.27 0.5314 0.5005 1940760 CBMicro_030381 COc1ccc(cc1OC)c2cc(C(=O)Nc3cc(ccc3Cl)[N+](=O)[O-])c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P04 compound treatment 0.343 -0.00265 -0.22 0.336 -0.00609 -0.54 -0.5371 -0.9214 1940761 CBMicro_030382 CN(/C(=N/S(=O)(=O)c1ccccc1)/c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P05 compound treatment 0.348 0.00235 0.2 0.352 0.00991 0.88 0.759 0.8439 1940762 CBMicro_030383 [O-][N+](=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P06 compound treatment 0.338 -0.00765 -0.63 0.342 -9.37E-5 -0.01 -0.4547 -0.7163 1940763 CBMicro_030384 Cc1cccc(NC(=O)CC2SC(=N)NC2=O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P07 compound treatment 0.358 0.0124 1.03 0.346 0.00391 0.35 0.9701 0.8961 1940764 CBMicro_030385 COc1ccc(CCNC(=O)COc2ccccc2[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P08 compound treatment 0.346 3.55E-4 0.03 0.342 -9.37E-5 -0.01 0.015 0.4886 1407384 CBMicro_030386 CC(=O)Oc1ccc(cc1)c2cccc(c2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P09 compound treatment 0.339 -0.00665 -0.55 0.34 -0.00209 -0.19 -0.5213 -0.8956 1443519 CBMicro_030387 Cc1cc(=O)oc2cc(OCC(=O)OCc3ccccc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P10 compound treatment 0.334 -0.0116 -0.97 0.337 -0.00509 -0.45 -1.0028 -0.9399 1137644 CBMicro_030388 CCOC(=O)c1c(NC(=O)c2cc3ccccc3o2)sc4CC(C)CCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P11 compound treatment 0.611 0.265 22.03 0.62 0.278 24.63 32.9922 0.9985 1940765 CBMicro_030389 OC(=O)CC1S/C(=N\N=C\c2ccc(cc2)[N+](=O)[O-])/NC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P12 compound treatment 0.386 0.0404 3.35 0.37 0.0279 2.47 4.1177 0.9888 1940766 CBMicro_030390 [O-][N+](=O)c1ccc(/C=C/C(=O)c2ccc(OC(F)F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P13 compound treatment 0.352 0.00635 0.53 0.353 0.0109 0.97 1.0565 0.9594 1305491 CBMicro_030391 COC(=O)c1ccc(COc2ccc3c(C)cc(=O)oc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P14 compound treatment 0.344 -0.00165 -0.14 0.344 0.00191 0.17 0.0229 0.1053 1195984 CBMicro_030392 COc1ccc(NC(=O)CCOc2ccccc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P15 compound treatment 0.372 0.0264 2.19 0.342 -9.37E-5 -0.01 1.5412 0.7044 1940767 CBMicro_030393 [O-][N+](=O)c1cccc(c1)N2C(=O)c3ccc(cc3C2=O)c4nc5cc(Cl)ccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P16 compound treatment 0.338 -0.00765 -0.63 0.338 -0.00409 -0.36 -0.7053 -0.9648 1231213 CBMicro_030394 Cc1cccc(CSCc2nnc(NC(=O)Nc3cccc(Cl)c3)s2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P17 compound treatment 0.345 -6.45E-4 -0.05 0.345 0.00291 0.26 0.1442 0.5483 1782258 CBMicro_030395 Cc1ccc(NC(=O)c2cc3cc(ccc3oc2=O)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P18 compound treatment 0.351 0.00535 0.44 0.349 0.00691 0.61 0.7471 0.9877 1203042 CBMicro_030396 COC(=O)c1cc(Cl)c(NC(=O)c2c(C)onc2c3ccccc3Cl)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P19 compound treatment 0.349 0.00335 0.28 0.35 0.00791 0.7 0.6924 0.9183 1940768 CBMicro_030397 COc1cc(NC(=O)c2cccnc2)c(OC)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P20 compound treatment 0.345 -6.45E-4 -0.05 0.341 -0.00109 -0.1 -0.1064 -0.9609 1781212 CBMicro_030398 [O-][N+](=O)c1ccc2nc(SCC(=O)NCC3CCCO3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P21 compound treatment 0.36 0.0144 1.19 0.352 0.00991 0.88 1.4635 0.9887 1355599 CBMicro_030399 CCOC(=O)c1c(c2ccccc2)n(Cc3ccccc3)c4ccc(OC(=O)C)cc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P22 compound treatment 0.336 -0.00965 -0.8 0.348 0.00591 0.52 -0.1961 -0.205 1940769 CBMicro_030400 [O-][N+](=O)c1ccc2nc(SCC(=O)NCCc3ccccc3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P23 positive control 0.089 -0.257 -21.31 0.091 -0.251 -22.25 -30.8007 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.1244 P24 positive control 0.09 -0.256 -21.22 0.094 -0.248 -21.99 -30.554 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A01 mock treatment 0.346 -0.0111 -0.92 0.33 -0.0184 -1.63 -1.8004 -0.9633 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A02 mock treatment 0.344 -0.0131 -1.08 0.334 -0.0144 -1.27 -1.6671 -0.9968 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A03 compound treatment 0.343 -0.0141 -1.17 0.344 -0.00437 -0.39 -1.0992 -0.8937 1938665 CBMicro_026241 Oc1ccccc1C(=O)N/N=C/c2c[nH]c3ccc(Br)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A04 compound treatment 0.347 -0.0101 -0.84 0.339 -0.00937 -0.83 -1.1777 -1.0 1938666 CBMicro_026242 C/C(=N\Nc1cccc2cccnc12)/c3cc(cs3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A05 compound treatment 0.327 -0.0301 -2.5 0.324 -0.0244 -2.16 -3.2917 -0.9974 1938667 CBMicro_026243 Clc1ccc(CSc2n[nH]c(=O)[nH]c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A06 compound treatment 0.339 -0.0181 -1.5 0.339 -0.00937 -0.83 -1.6473 -0.9611 1144371 CBMicro_026244 COc1ccc(CC(NC(=O)Cc2ccc(OC)c(OC)c2)C(=O)O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A07 compound treatment 0.35 -0.00706 -0.59 0.36 0.0116 1.03 0.3144 0.2651 1570931 CBMicro_026245 Cc1cccc2c3nnc(NN)nc3[nH]c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A08 compound treatment 0.337 -0.0201 -1.67 0.338 -0.0104 -0.92 -1.8274 -0.9607 1606945 CBMicro_026246 Cc1ccc(NC(=O)C2CC=CCC2C(=O)O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A09 compound treatment 0.344 -0.0131 -1.08 0.34 -0.00837 -0.74 -1.2911 -0.9828 1938668 CBMicro_026247 Cc1cccc2c3nnc(N/N=C\c4ccc(o4)c5ccccc5Cl)nc3[nH]c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A10 compound treatment 0.339 -0.0181 -1.5 0.336 -0.0124 -1.1 -1.8353 -0.9881 1938669 CBMicro_026248 C/C=C/COC(=O)C1=C(C)NC(=O)NC1c2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A11 compound treatment 0.342 -0.0151 -1.25 0.337 -0.0114 -1.01 -1.5965 -0.9943 1938670 CBMicro_026249 CC1(C)CC(CC(C)(C)N1)NC(=O)C(=O)NCCc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A12 compound treatment 0.419 0.0619 5.14 0.418 0.0696 6.17 7.9995 0.9959 1938671 CBMicro_026250 CC(NC(=O)OC(C)(C)C)C(=O)Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A13 compound treatment 0.396 0.0389 3.23 0.388 0.0396 3.51 4.7694 0.9991 1938672 CBMicro_026251 CCOc1cccc(/C=N/c2cccc3nsnc23)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A14 compound treatment 0.348 -0.00906 -0.75 0.345 -0.00337 -0.3 -0.743 -0.918 1938673 CBMicro_026252 COc1ccc(NC(=O)/C=C/c2cc(OC)ccc2OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A15 compound treatment 0.341 -0.0161 -1.33 0.333 -0.0154 -1.36 -1.9059 -0.9999 1938674 CBMicro_026253 COc1ccc(/C=C/C(=O)NCCc2nc3ccccc3[nH]2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A16 compound treatment 0.338 -0.0191 -1.58 0.34 -0.00837 -0.74 -1.6433 -0.9403 1938675 CBMicro_026254 Cc1cc(NC(=O)CN2C(=O)S/C(=C\c3ccccc3)/C2=O)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A17 compound treatment 0.342 -0.0151 -1.25 0.337 -0.0114 -1.01 -1.5965 -0.9943 1710330 CBMicro_026255 Cc1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A18 compound treatment 0.34 -0.0171 -1.42 0.334 -0.0144 -1.27 -1.9019 -0.9986 1693745 CBMicro_026256 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCc2ccco2)c3cc(C)cc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A19 compound treatment 0.34 -0.0171 -1.42 0.333 -0.0154 -1.36 -1.9646 -0.9998 1938676 CBMicro_026257 OC(=O)c1ccc(/N=C\2/SC(Cc3ccccc3)C(=O)N2CC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A20 compound treatment 0.337 -0.0201 -1.67 0.335 -0.0134 -1.18 -2.0154 -0.9861 1938677 CBMicro_026258 CC(=O)C1=C(C)NC(=O)NC1c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A21 compound treatment 0.335 -0.0221 -1.83 0.328 -0.0204 -1.8 -2.5714 -1.0 1938678 CBMicro_026259 Cc1cc2/C(=N\Nc3cccc4cccnc34)/C(=O)Nc2c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A22 compound treatment 0.337 -0.0201 -1.67 0.331 -0.0174 -1.54 -2.266 -0.9992 1938679 CBMicro_026260 Oc1ccccc1/C=N/NC(=O)CSc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A23 positive control 0.085 -0.272 -22.59 0.086 -0.262 -23.25 -32.4122 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 A24 positive control 0.086 -0.271 -22.5 0.088 -0.26 -23.07 -32.2282 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B01 mock treatment 0.358 9.37E-4 0.08 0.328 -0.0204 -1.8 -1.2212 -0.676 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B02 mock treatment 0.358 9.37E-4 0.08 0.346 -0.00237 -0.21 -0.0933 -0.4169 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B03 compound treatment 0.534 0.177 14.69 0.517 0.169 14.94 20.9542 1.0 1938680 CBMicro_026261 N(/N=C/C=C/c1ccco1)c2cccc3cccnc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B04 compound treatment 0.363 0.00594 0.49 0.359 0.0106 0.94 1.0149 0.9543 1938681 CBMicro_026262 O=C(NCc1ccccc1)/C(=C/c2ccco2)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B05 compound treatment 0.355 -0.00206 -0.17 0.348 -3.67E-4 -0.03 -0.1441 -0.8265 1938682 CBMicro_026263 Cc1ccc2[nH]c3nc(N/N=C/c4ccc(o4)c5ccc(Cl)cc5)nnc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B06 compound treatment 0.364 0.00694 0.58 0.353 0.00463 0.41 0.6976 0.9862 1938683 CBMicro_026264 COc1cc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)c(cc1OC)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B07 compound treatment 0.371 0.0139 1.16 0.354 0.00563 0.5 1.1712 0.9294 1058072 CBMicro_026265 COc1cc(ccc1NC(=O)c2ccccc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B08 compound treatment 0.357 -6.25E-5 -0.01 0.35 0.00163 0.14 0.0987 0.6813 1544042 CBMicro_026266 Cc1cc(c2nc3ccccc3[nH]2)c4ccccc4n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B09 compound treatment 0.358 9.37E-4 0.08 0.352 0.00363 0.32 0.2827 0.8534 1938684 CBMicro_026267 CC/1=NN(C(=O)\C1=C\Nc2ccc(Cl)cc2Cl)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B10 compound treatment 0.359 0.00194 0.16 0.358 0.00963 0.85 0.7174 0.8258 1723614 CBMicro_026268 CCOC(=O)c1ccc(NC(=S)NCC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B11 compound treatment 0.501 0.144 11.95 0.455 0.107 9.45 15.1318 0.9932 1938685 CBMicro_026269 Oc1ccccc1C(=O)N/N=C/2\C(=O)Nc3ccc(F)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B12 compound treatment 0.369 0.0119 0.99 0.364 0.0156 1.39 1.6804 0.9865 1938686 CBMicro_026270 Cc1ccccc1OCC(=O)Nc2cccc(c2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B13 compound treatment 0.355 -0.00206 -0.17 0.358 0.00963 0.85 0.4826 0.5542 1938687 CBMicro_026271 Brc1ccc(cc1)N2CC(CC2=O)C(=O)NCCCCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B14 compound treatment 0.35 -0.00706 -0.59 0.35 0.00163 0.14 -0.3122 -0.517 1938688 CBMicro_026272 Cc1cc(C)nc(SCC(=O)N/N=C/c2ccc(Cl)cc2Cl)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B15 compound treatment 0.363 0.00594 0.49 0.356 0.00763 0.68 0.8269 0.9879 1938689 CBMicro_026273 Oc1ccc(/C=N/n2c(S)nnc2c3ccccc3)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B16 compound treatment 0.354 -0.00306 -0.25 0.347 -0.00137 -0.12 -0.2654 -0.9425 1414672 CBMicro_026274 COc1ccc(CCNC(=O)C2CC2(c3ccccc3)c4ccccc4)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B17 compound treatment 0.429 0.0719 5.97 0.428 0.0796 7.06 9.2132 0.9966 1938690 CBMicro_026275 CN1C(=O)N(C)C(=O)C(=Cc2c(C)nn(c2O)c3ccccc3)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B18 compound treatment 0.356 -0.00106 -0.09 0.35 0.00163 0.14 0.04 0.2359 1636888 CBMicro_026276 COc1ccc(cc1NC(=O)C(C)Oc2ccccc2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B19 compound treatment 0.349 -0.00806 -0.67 0.348 -3.67E-4 -0.03 -0.4963 -0.7406 1518856 CBMicro_026277 CCN(CC)c1ccc(NC(=O)COc2cccc(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B20 compound treatment 0.355 -0.00206 -0.17 0.346 -0.00237 -0.21 -0.2694 -0.9949 1327739 CBMicro_026278 COC(=O)c1ccc(cc1NC(=O)C(C)Oc2ccccc2)C(=O)Nc3cc(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B21 compound treatment 0.353 -0.00406 -0.34 0.352 0.00363 0.32 -0.0108 -0.0232 1938691 CBMicro_026279 Cc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(C)c3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B22 compound treatment 0.346 -0.0111 -0.92 0.346 -0.00237 -0.21 -0.7977 -0.8468 1298202 CBMicro_026280 CC(Oc1ccc(Cl)cc1C)C(=O)NCCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B23 positive control 0.087 -0.27 -22.42 0.086 -0.262 -23.25 -32.2948 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 B24 positive control 0.085 -0.272 -22.59 0.085 -0.263 -23.34 -32.4749 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C01 mock treatment 0.366 0.00894 0.74 0.344 -0.00437 -0.39 0.251 0.3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C02 mock treatment 0.365 0.00794 0.66 0.351 0.00263 0.23 0.631 0.9026 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C03 compound treatment 0.365 0.00794 0.66 0.36 0.0116 1.03 1.195 0.9766 1938692 CBMicro_026281 O=C(Oc1cccc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)c1)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C04 compound treatment 0.362 0.00494 0.41 0.364 0.0156 1.39 1.2695 0.8787 1224521 CBMicro_026282 Brc1ccc2c(Br)c(OCC(=O)NCc3ccccc3)ccc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C05 compound treatment 0.368 0.0109 0.91 0.356 0.00763 0.68 1.1204 0.9895 1306097 CBMicro_026283 Cc1ccc(N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cccc(C)c4C)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C06 compound treatment 0.361 0.00394 0.33 0.34 -0.00837 -0.74 -0.2932 -0.3618 1938693 CBMicro_026284 CN1CCN(CC1)c2ccc([N+](=O)[O-])c(NCCOc3ccc(Cl)cc3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C07 compound treatment 0.361 0.00394 0.33 0.35 0.00163 0.14 0.3335 0.9329 1654706 CBMicro_026285 OC(=O)C1CCCCC1C(=O)NCCc2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C08 compound treatment 0.39 0.0329 2.73 0.393 0.0446 3.96 4.7305 0.9837 1938694 CBMicro_026286 Cc1ccc(CC2S/C(=N\N=C\c3ccco3)/N(CC=C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C09 compound treatment 0.411 0.0539 4.48 0.379 0.0306 2.71 5.0859 0.9712 1938695 CBMicro_026287 Cc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(O)c3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C10 compound treatment 0.359 0.00194 0.16 0.35 0.00163 0.14 0.2161 0.9986 1938696 CBMicro_026288 O=C(N/N=C/c1ccco1)C(=O)N2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C11 compound treatment 0.443 0.0859 7.13 0.436 0.0876 7.77 10.5364 0.9991 1938697 CBMicro_026289 [O-][N+](=O)c1cccc(c1)c2ccc(/C=C/C(=O)Nc3ccc(Cl)cc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C12 compound treatment 0.53 0.173 14.36 0.515 0.167 14.77 20.5941 0.9999 1938698 CBMicro_026290 O=C(/C=C/c1ccc(o1)c2ccccc2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C13 compound treatment 0.388 0.0309 2.57 0.379 0.0306 2.71 3.7358 0.9996 1938699 CBMicro_026291 CCOc1cc(/C=N/NC(=O)COc2cccc(C)c2)ccc1OC(=O)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C14 compound treatment 0.358 9.37E-4 0.08 0.35 0.00163 0.14 0.1574 0.9577 1567194 CBMicro_026292 CN(C)c1ccc(NC(=O)c2ccc(F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C15 compound treatment 0.362 0.00494 0.41 0.354 0.00563 0.5 0.6429 0.9952 1938700 CBMicro_026293 CCCCC(CC)CNC(=O)C(=O)NCC1CCCO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C16 compound treatment 0.369 0.0119 0.99 0.372 0.0236 2.09 2.1818 0.9416 1938701 CBMicro_026294 CCOc1cc(/C=C\2/SC(=O)N(CC=C)C2=O)cc(Br)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C17 compound treatment 0.358 9.37E-4 0.08 0.353 0.00463 0.41 0.3454 0.8264 1187956 CBMicro_026295 CCSc1nnc-2c(OC(Nc3ccccc32)c4ccc(O)c(O)c4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C18 compound treatment 0.358 9.37E-4 0.08 0.354 0.00563 0.5 0.408 0.8076 1938702 CBMicro_026296 Brc1cccc(c1)N2C(=O)/C(=C\c3cccs3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C19 compound treatment 0.359 0.00194 0.16 0.353 0.00463 0.41 0.4041 0.9163 1938703 CBMicro_026297 COc1cc(/C=N/Nc2ncc(C)c(=O)[nH]2)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C20 compound treatment 0.36 0.00294 0.24 0.35 0.00163 0.14 0.2748 0.969 1510766 CBMicro_026298 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)c5ccccc5C4=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C21 compound treatment 0.42 0.0629 5.23 0.409 0.0606 5.37 7.4942 0.9999 1938704 CBMicro_026299 COc1ccccc1/C=C/2\SC(=S)N(CC(=O)NNc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C22 compound treatment 0.358 9.37E-4 0.08 0.361 0.0126 1.12 0.8467 0.7544 1394320 CBMicro_026300 CC(=C1C(=O)c2ccccc2C1=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C23 positive control 0.085 -0.272 -22.59 0.083 -0.265 -23.52 -32.6002 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 C24 positive control 0.085 -0.272 -22.59 0.088 -0.26 -23.07 -32.2869 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D01 mock treatment 0.362 0.00494 0.41 0.349 6.33E-4 0.06 0.3295 0.7965 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D02 mock treatment 0.355 -0.00206 -0.17 0.349 6.33E-4 0.06 -0.0814 -0.4517 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D03 compound treatment 0.467 0.11 9.13 0.366 0.0176 1.56 7.5587 0.8163 1938705 CBMicro_026301 CSCCC(N1C(=O)/C(=C/c2ccccc2Cl)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D04 compound treatment 0.375 0.0179 1.49 0.373 0.0246 2.18 2.5966 0.9826 1938706 CBMicro_026302 CC/1=NN(C(=O)\C1=C/Nc2ccccc2C(=O)O)c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D05 compound treatment 0.386 0.0289 2.4 0.369 0.0206 1.83 2.9917 0.9909 1618890 CBMicro_026303 Brc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D06 compound treatment 0.37 0.0129 1.07 0.362 0.0136 1.21 1.6138 0.9983 1938707 CBMicro_026304 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D07 compound treatment 0.359 0.00194 0.16 0.359 0.0106 0.94 0.7801 0.816 1135301 CBMicro_026305 CCc1ccc(NC(=O)C2CN(C3CCCCC3)C(=O)C2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D08 compound treatment 0.36 0.00294 0.24 0.358 0.00963 0.85 0.7761 0.8741 1938708 CBMicro_026306 Cc1nc2ccccc2c(=O)n1/N=C/c3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D09 compound treatment 0.363 0.00594 0.49 0.358 0.00963 0.85 0.9522 0.9659 1227210 CBMicro_026307 Cc1cccc(OCC(=O)Nc2ccc(cc2)N3CCOCC3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D10 compound treatment 0.367 0.00994 0.83 0.347 -0.00137 -0.12 0.4977 0.5969 1938709 CBMicro_026308 OC(=O)CCC(=O)NNC(=O)c1ccncc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D11 compound treatment 0.402 0.0449 3.73 0.391 0.0426 3.78 5.3096 1.0 1303410 CBMicro_026309 Cc1ccc(cc1)C(=O)NCC(=O)c2ccc(cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D12 compound treatment 0.359 0.00194 0.16 0.35 0.00163 0.14 0.2161 0.9986 1345947 CBMicro_026310 O=C1C2C3C=CC(C2C(=O)N1Cc4ccccc4)C3=C5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D13 compound treatment 0.675 0.318 26.39 0.683 0.335 29.66 39.6338 0.9983 1938710 CBMicro_026311 CCOc1cc(/C=C/2\SC(=S)N(NC(=O)c3cccc(c3)[N+](=O)[O-])C2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D14 compound treatment 0.367 0.00994 0.83 0.354 0.00563 0.5 0.9364 0.971 1555195 CBMicro_026312 O=C(Nc1nnc(COc2ccccc2)s1)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D15 compound treatment 0.384 0.0269 2.24 0.376 0.0276 2.45 3.313 0.999 1150220 CBMicro_026313 Clc1cccc(c1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D16 compound treatment 0.355 -0.00206 -0.17 0.35 0.00163 0.14 -0.0187 -0.0835 1938711 CBMicro_026314 O=C(N1CCOCC1)C(=O)c2c[nH]c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D17 compound treatment 0.5 0.143 11.87 0.506 0.158 13.97 18.269 0.9967 1938712 CBMicro_026315 Cc1nn(c(O)c1/C=N/Nc2ccccn2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D18 compound treatment 0.354 -0.00306 -0.25 0.346 -0.00237 -0.21 -0.3281 -0.9954 1938713 CBMicro_026316 COc1ccc(CCNC=C2C(=O)NC(=O)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D19 compound treatment 0.363 0.00594 0.49 0.354 0.00563 0.5 0.7016 1.0 1938714 CBMicro_026317 COc1ccccc1/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(C)c3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D20 compound treatment 0.357 -6.25E-5 -0.01 0.355 0.00663 0.59 0.412 0.7008 1177358 CBMicro_026318 CC1(C)CC(=O)C=C(C1)NCCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D21 compound treatment 0.363 0.00594 0.49 0.354 0.00563 0.5 0.7016 1.0 1938715 CBMicro_026319 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(cc2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D22 compound treatment 0.351 -0.00606 -0.5 0.353 0.00463 0.41 -0.0655 -0.1009 1478860 CBMicro_026320 Fc1ccc(cc1)C(=O)N(C2CS(=O)(=O)C=C2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D23 positive control 0.085 -0.272 -22.59 0.084 -0.264 -23.43 -32.5375 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 D24 positive control 0.086 -0.271 -22.5 0.089 -0.259 -22.99 -32.1655 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E01 mock treatment 0.361 0.00394 0.33 0.349 6.33E-4 0.06 0.2708 0.8166 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E02 mock treatment 0.359 0.00194 0.16 0.351 0.00263 0.23 0.2788 0.9835 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E03 compound treatment 0.362 0.00494 0.41 0.357 0.00863 0.77 0.8309 0.9572 1938716 CBMicro_026321 CCN(CC)CCOC(=O)c1ccc(O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E04 compound treatment 0.356 -0.00106 -0.09 0.352 0.00363 0.32 0.1653 0.4952 1779209 CBMicro_026322 [O-][N+](=O)c1cccc(c1)C(=O)Nc2ncc(Cc3ccc(Cl)c(Cl)c3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E05 compound treatment 0.355 -0.00206 -0.17 0.354 0.00563 0.5 0.2319 0.4395 1517631 CBMicro_026323 Cc1nnc(s1)N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E06 compound treatment 0.351 -0.00606 -0.5 0.35 0.00163 0.14 -0.2535 -0.4841 1938717 CBMicro_026324 Nc1nonc1C(=O)N/N=C/c2cccc(OCC(=O)O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E07 compound treatment 0.398 0.0409 3.4 0.393 0.0446 3.96 5.2001 0.9971 1938718 CBMicro_026325 O=C/1OC(=C\C1=C\c2ccc3OCOc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E08 compound treatment 0.397 0.0399 3.32 0.391 0.0426 3.78 5.0161 0.9979 1938719 CBMicro_026326 CC/1=NN(C(=O)\C1=C\Nc2cccc(Cl)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E09 compound treatment 0.366 0.00894 0.74 0.358 0.00963 0.85 1.1283 0.9976 1938720 CBMicro_026327 OC(=O)/C(=C/c1ccccc1)/c2c(F)c(F)c(F)c(F)c2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E10 compound treatment 0.407 0.0499 4.15 0.402 0.0536 4.75 6.2924 0.9977 1938721 CBMicro_026328 O=C(CSc1nc2ccccc2s1)CSc3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E11 compound treatment 0.116 -0.241 -20.01 0.104 -0.244 -21.66 -29.4644 -0.9992 1084506 CBMicro_026329 CC(=O)c1ccc(cc1)N2C(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E12 compound treatment 0.356 -0.00106 -0.09 0.353 0.00463 0.41 0.228 0.5428 1318187 CBMicro_026330 CCC(=O)Nc1ccc(cc1)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E13 compound treatment 0.368 0.0109 0.91 0.37 0.0216 1.92 1.9977 0.9417 1938722 CBMicro_026331 COc1ccc(/C=N/NC(=S)NC2CCS(=O)(=O)C2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E14 compound treatment 0.355 -0.00206 -0.17 0.35 0.00163 0.14 -0.0187 -0.0835 1136987 CBMicro_026332 CC(C)(C)NCC(O)COC1CCC(CC1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E15 compound treatment 0.373 0.0159 1.32 0.372 0.0236 2.09 2.4166 0.9755 1938723 CBMicro_026333 CC/1=NN(C(=O)\C1=C\c2c(C)nn(c2O)c3cccc(Cl)c3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E16 compound treatment 0.396 0.0389 3.23 0.367 0.0186 1.65 3.4534 0.9514 1159420 CBMicro_026334 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(Cl)c(c2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E17 compound treatment 0.367 0.00994 0.83 0.364 0.0156 1.39 1.563 0.9693 1605213 CBMicro_026335 CCOC(=O)Cc1csc(NC(=O)COc2cc(C)ccc2C(C)C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E18 compound treatment 0.356 -0.00106 -0.09 0.347 -0.00137 -0.12 -0.148 -0.9879 1938724 CBMicro_026336 COc1ccccc1C(=O)Oc2ccc(C)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E19 compound treatment 0.384 0.0269 2.24 0.388 0.0396 3.51 4.0649 0.9762 1388898 CBMicro_026337 Clc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E20 compound treatment 0.365 0.00794 0.66 0.357 0.00863 0.77 1.007 0.9972 1938725 CBMicro_026338 CC(Oc1ccccc1)C(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E21 compound treatment 0.357 -6.25E-5 -0.01 0.353 0.00463 0.41 0.2867 0.6981 1271198 CBMicro_026339 CC(C)c1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E22 compound treatment 0.353 -0.00406 -0.34 0.352 0.00363 0.32 -0.0108 -0.0232 1705607 CBMicro_026340 Cc1ccc(C)c(c1)N2C(=O)C3C4C=CC(C3C2=O)C4=C5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E23 positive control 0.086 -0.271 -22.5 0.084 -0.264 -23.43 -32.4788 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 E24 positive control 0.088 -0.269 -22.34 0.09 -0.258 -22.9 -31.9854 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F01 mock treatment 0.358 9.37E-4 0.08 0.344 -0.00437 -0.39 -0.2186 -0.5538 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F02 mock treatment 0.355 -0.00206 -0.17 0.349 6.33E-4 0.06 -0.0814 -0.4517 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F03 compound treatment 0.559 0.202 16.76 0.557 0.209 18.49 24.9284 0.9988 1938726 CBMicro_026341 COc1cccc(/C=C/2\SC(=S)N(NC(=O)c3cccc(c3)[N+](=O)[O-])C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F04 compound treatment 0.374 0.0169 1.41 0.364 0.0156 1.39 1.974 1.0 1688825 CBMicro_026342 COc1ccc2oc(=O)c(cc2c1)c3csc(Nc4ccccc4C)n3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F05 compound treatment 0.354 -0.00306 -0.25 0.356 0.00763 0.68 0.2986 0.4131 1621772 CBMicro_026343 COc1ccc(cc1)N2CC(CC2=O)C(=O)OCC(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F06 compound treatment 0.353 -0.00406 -0.34 0.358 0.00963 0.85 0.3652 0.3978 1741280 CBMicro_026344 COC(=O)c1ccc(CN(c2cccc3cccnc23)S(=O)(=O)c4ccc(C)cc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F07 compound treatment 0.443 0.0859 7.13 0.42 0.0716 6.35 9.5337 0.9983 1938727 CBMicro_026345 CCOC(=O)c1ccc(NC(=O)CN2C(=O)/C(=C/c3ccc(C)cc3)/SC2=S)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F08 compound treatment 0.195 -0.162 -13.45 0.186 -0.162 -14.39 -19.6883 -0.9994 1465994 CBMicro_026346 CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F09 compound treatment 0.418 0.0609 5.06 0.398 0.0496 4.4 6.6875 0.9976 1938728 CBMicro_026347 [O-][N+](=O)c1cc2n(Cc3ccccc3Cl)c(=O)n(Cc4ccccc4Cl)c2cc1N5CCOCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F10 compound treatment 0.363 0.00594 0.49 0.382 0.0336 2.98 2.4562 0.813 1938729 CBMicro_026348 CC(C)(C)c1ccc(cc1)C(=O)Nc2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F11 compound treatment 0.391 0.0339 2.82 0.376 0.0276 2.45 3.7239 0.9976 1938730 CBMicro_026349 FC(F)(F)c1cccc(CCNC(=O)C(=O)Nc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F12 compound treatment 0.356 -0.00106 -0.09 0.37 0.0216 1.92 1.2933 0.6739 1938731 CBMicro_026350 CCN(CC)CC(O)COc1ccccc1C(=O)CCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F13 compound treatment 0.368 0.0109 0.91 0.372 0.0236 2.09 2.1231 0.93 1671068 CBMicro_026351 CCN(CC)c1ccc(NC(=O)COc2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F14 compound treatment 0.359 0.00194 0.16 0.354 0.00563 0.5 0.4668 0.8899 1938732 CBMicro_026352 CC(=C1C2C=CC1C3C2C(=O)N(C3=O)c4ccc(F)cc4)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F15 compound treatment 0.361 0.00394 0.33 0.353 0.00463 0.41 0.5215 0.9936 1938733 CBMicro_026353 N(c1nc(cs1)c2ccccn2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F16 compound treatment 0.358 9.37E-4 0.08 0.356 0.00763 0.68 0.5334 0.7833 1938734 CBMicro_026354 Brc1ccc(cc1)C(=O)NNc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F17 compound treatment 0.361 0.00394 0.33 0.357 0.00863 0.77 0.7722 0.9281 1233037 CBMicro_026355 COc1ccc(CC(=O)N(c2ccccc2)c3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F18 compound treatment 0.377 0.0199 1.66 0.364 0.0156 1.39 2.1501 0.9961 1328855 CBMicro_026356 COc1ccc(OC)c(NC(=O)c2ccccc2CCc3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F19 compound treatment 0.388 0.0309 2.57 0.401 0.0526 4.66 5.1144 0.9605 1938735 CBMicro_026357 OC(=O)C1CSC(N1)c2ccc(Cl)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F20 compound treatment 0.357 -6.25E-5 -0.01 0.356 0.00763 0.68 0.4747 0.7017 1231322 CBMicro_026358 Cc1c(NC(=S)NCc2ccco2)c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F21 compound treatment 0.354 -0.00306 -0.25 0.354 0.00563 0.5 0.1732 0.3092 1533825 CBMicro_026359 O=C(NCc1cccnc1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F22 compound treatment 0.355 -0.00206 -0.17 0.35 0.00163 0.14 -0.0187 -0.0835 1938736 CBMicro_026360 COc1ccc(OC)c(/C=N/NC(=O)CSc2ncccn2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F23 positive control 0.087 -0.27 -22.42 0.085 -0.263 -23.34 -32.3575 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 F24 positive control 0.086 -0.271 -22.5 0.089 -0.259 -22.99 -32.1655 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G01 mock treatment 0.358 9.37E-4 0.08 0.343 -0.00537 -0.48 -0.2813 -0.5836 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G02 mock treatment 0.35 -0.00706 -0.59 0.345 -0.00337 -0.3 -0.6256 -0.9509 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G03 compound treatment 0.355 -0.00206 -0.17 0.343 -0.00537 -0.48 -0.4574 -0.9048 1653903 CBMicro_026361 O=C(Cc1ccccc1)Nc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G04 compound treatment 0.353 -0.00406 -0.34 0.348 -3.67E-4 -0.03 -0.2615 -0.7717 1381802 CBMicro_026362 O=C(OCC#C)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G05 compound treatment 0.361 0.00394 0.33 0.358 0.00963 0.85 0.8348 0.9132 1643055 CBMicro_026363 CCN(CC(O)Cn1c2ccccc2c3ccccc13)S(=O)(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G06 compound treatment 0.372 0.0149 1.24 0.367 0.0186 1.65 2.0445 0.99 1666764 CBMicro_026364 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccc(OC)cc2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G07 compound treatment 0.353 -0.00406 -0.34 0.345 -0.00337 -0.3 -0.4495 -0.9981 1938737 CBMicro_026365 COc1ccc(OC)c(/C=C/C(=O)NCCc2nc3ccccc3[nH]2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G08 compound treatment 0.68 0.323 26.81 0.662 0.314 27.79 38.6114 0.9998 1938738 CBMicro_026366 COc1ccccc1/C=C/2\SC(=S)N(NC(=O)c3cccc(c3)[N+](=O)[O-])C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G09 compound treatment 0.369 0.0119 0.99 0.357 0.00863 0.77 1.2418 0.9918 1211344 CBMicro_026367 CCN(CC)c1ccc(NC(=O)c2ccc(F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G10 compound treatment 0.417 0.0599 4.98 0.4 0.0516 4.58 6.7541 0.9991 1938739 CBMicro_026368 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)NNC(=O)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G11 compound treatment 0.353 -0.00406 -0.34 0.352 0.00363 0.32 -0.0108 -0.0232 1938740 CBMicro_026369 Cc1ccc2[nH]c3nc(N/N=C/4\C(=O)Nc5c4cc(Br)cc5Br)nnc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G12 compound treatment 0.41 0.0529 4.39 0.408 0.0596 5.28 6.8445 0.9958 1938741 CBMicro_026370 COc1ccc(/C=C\2/C=C(OC2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G13 compound treatment 0.355 -0.00206 -0.17 0.358 0.00963 0.85 0.4826 0.5542 1938742 CBMicro_026371 COc1ccc(/C=N\NC(=O)CNc2ccccc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G14 compound treatment 0.398 0.0409 3.4 0.403 0.0546 4.84 5.8268 0.985 1475621 CBMicro_026372 COn1c(C)c(C)c2c1ccc3nonc32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G15 compound treatment 0.459 0.102 8.46 0.457 0.109 9.63 12.7916 0.9979 1938743 CBMicro_026373 COc1cc(/C=C/2\SC(=NC2=O)c3ccc(C)cc3)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G16 compound treatment 0.351 -0.00606 -0.5 0.347 -0.00137 -0.12 -0.4415 -0.8529 1938744 CBMicro_026374 COC(=O)C1=NNC2C1C(=O)N(Cc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G17 compound treatment 0.342 -0.0151 -1.25 0.365 0.0166 1.47 0.1581 0.0818 1133426 CBMicro_026375 COc1ccc(CCNC(=O)COc2ccccc2C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G18 compound treatment 0.372 0.0149 1.24 0.376 0.0276 2.45 2.6085 0.9503 1398048 CBMicro_026376 OC(=O)c1c(NS(=O)(=O)c2ccccc2)sc3CCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G19 compound treatment 0.35 -0.00706 -0.59 0.352 0.00363 0.32 -0.1869 -0.2794 1938745 CBMicro_026377 Cc1cc(=O)[nH]c(N/N=C/c2ccc(O)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G20 compound treatment 0.35 -0.00706 -0.59 0.354 0.00563 0.5 -0.0616 -0.08 1938746 CBMicro_026378 Clc1ccccc1Cc2cnc(NC(=O)CCN3C(=O)/C(=C/c4ccccc4Cl)/SC3=S)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G21 compound treatment 0.352 -0.00506 -0.42 0.355 0.00663 0.59 0.1185 0.164 1382204 CBMicro_026379 CCN(CC)c1ccc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G22 compound treatment 0.351 -0.00606 -0.5 0.345 -0.00337 -0.3 -0.5669 -0.9688 1938747 CBMicro_026380 COc1ccc(cc1Cl)N(CC(=O)NN=C2CCN(C)CC2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G23 positive control 0.087 -0.27 -22.42 0.085 -0.263 -23.34 -32.3575 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 G24 positive control 0.087 -0.27 -22.42 0.092 -0.256 -22.72 -31.9188 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H01 mock treatment 0.358 9.37E-4 0.08 0.343 -0.00537 -0.48 -0.2813 -0.5836 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H02 mock treatment 0.353 -0.00406 -0.34 0.34 -0.00837 -0.74 -0.7628 -0.9364 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H03 compound treatment 0.352 -0.00506 -0.42 0.346 -0.00237 -0.21 -0.4455 -0.9484 1386456 CBMicro_026381 Cc1ccc(cc1)C(=O)NCC(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H04 compound treatment 0.368 0.0109 0.91 0.364 0.0156 1.39 1.6217 0.979 1677109 CBMicro_026382 NS(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H05 compound treatment 0.352 -0.00506 -0.42 0.351 0.00263 0.23 -0.1322 -0.2749 1938748 CBMicro_026383 c1ccc(nc1)c2nnc([nH]2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H06 compound treatment 0.358 9.37E-4 0.08 0.361 0.0126 1.12 0.8467 0.7544 1938749 CBMicro_026384 NC(=O)N/N=C\1/C(=O)N(Cc2ccccc2)c3ccc(Br)cc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H07 compound treatment 0.355 -0.00206 -0.17 0.341 -0.00737 -0.65 -0.5827 -0.8634 1520409 CBMicro_026385 CCc1ccc(NC(=O)C2CCCCC2C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H08 compound treatment 0.441 0.0839 6.97 0.439 0.0906 8.03 10.607 0.9975 1938750 CBMicro_026386 CC/1=NN(C(=O)\C1=C/Nc2nnc(s2)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H09 compound treatment 0.347 -0.0101 -0.84 0.356 0.00763 0.68 -0.1124 -0.1045 1938751 CBMicro_026387 OCCN1C(=O)C2C(C3C(=O)CC2c4ccccc34)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H10 compound treatment 0.358 9.37E-4 0.08 0.354 0.00563 0.5 0.408 0.8076 1938752 CBMicro_026388 Clc1c(Cl)c(N2CCOCC2)c3C(=O)c4ccccc4C(=O)c3c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H11 compound treatment 0.348 -0.00906 -0.75 0.349 6.33E-4 0.06 -0.4923 -0.6525 1406360 CBMicro_026389 O=C(Nc1ccc(cc1)N2CCOCC2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H12 compound treatment 0.376 0.0189 1.57 0.355 0.00663 0.59 1.5274 0.91 1938753 CBMicro_026390 FC(F)(F)c1cccc(NC(=O)C2C3CCC=CCCC23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H13 compound treatment 0.353 -0.00406 -0.34 0.355 0.00663 0.59 0.1772 0.2615 1286135 CBMicro_026391 CC(C)(C)C(=O)Nc1ccc(cc1)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H14 compound treatment 0.387 0.0299 2.49 0.384 0.0356 3.16 3.9904 0.993 1337245 CBMicro_026392 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)c4cccc(F)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H15 compound treatment 0.37 0.0129 1.07 0.351 0.00263 0.23 0.9245 0.8411 1222486 CBMicro_026393 Brc1ccc(cc1)C(=O)CNC(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H16 compound treatment 0.353 -0.00406 -0.34 0.359 0.0106 0.94 0.4279 0.4275 1594034 CBMicro_026394 COc1ccc(OC)c(NC(=O)C(C)Oc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H17 compound treatment 0.351 -0.00606 -0.5 0.342 -0.00637 -0.56 -0.7549 -0.9984 1406654 CBMicro_026395 Cc1ccc(NC(=O)c2ccco2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H18 compound treatment 0.349 -0.00806 -0.67 0.343 -0.00537 -0.48 -0.8096 -0.986 1938754 CBMicro_026396 CCc1c(C)n[n+]2cnn(Cc3ccccc3Cl)c2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H19 compound treatment 0.481 0.124 10.29 0.523 0.175 15.48 18.219 0.9803 1938755 CBMicro_026397 COc1ccc(/C=C/2\SC(=O)N(CC(=O)Nc3nccs3)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H20 compound treatment 0.437 0.0799 6.64 0.487 0.139 12.29 13.3801 0.9582 1938756 CBMicro_026398 Oc1ccc(/C=N/NC(=O)c2cnccn2)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H21 compound treatment 0.347 -0.0101 -0.84 0.344 -0.00437 -0.39 -0.8643 -0.9388 1779731 CBMicro_026399 OC(=O)c1cccnc1SCc2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H22 compound treatment 0.35 -0.00706 -0.59 0.349 6.33E-4 0.06 -0.3749 -0.6365 1456174 CBMicro_026400 COC(=O)CN(c1cc(OC)ccc1OC)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H23 positive control 0.088 -0.269 -22.34 0.085 -0.263 -23.34 -32.2988 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 H24 positive control 0.087 -0.27 -22.42 0.092 -0.256 -22.72 -31.9188 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I01 mock treatment 0.361 0.00394 0.33 0.35 0.00163 0.14 0.3335 0.9329 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I02 mock treatment 0.354 -0.00306 -0.25 0.351 0.00263 0.23 -0.0148 -0.0428 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I03 compound treatment 0.363 0.00594 0.49 0.358 0.00963 0.85 0.9522 0.9659 1938757 CBMicro_026401 Clc1ccc(cc1)N2C(=O)CC(N3CCN(CC3)c4ccccc4Cl)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I04 compound treatment 0.364 0.00694 0.58 0.359 0.0106 0.94 1.0736 0.9721 1938758 CBMicro_026402 Clc1ccccc1C(=O)NN2C(=O)CSC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I05 compound treatment 0.363 0.00594 0.49 0.355 0.00663 0.59 0.7642 0.9962 1938759 CBMicro_026403 COc1ccc(OC)c(c1)N2C(=O)CCC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I06 compound treatment 0.38 0.0229 1.9 0.377 0.0286 2.54 3.1408 0.99 1480968 CBMicro_026404 OC(=O)c1ccc(cc1)N2Cc3ccccc3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I07 compound treatment 0.359 0.00194 0.16 0.34 -0.00837 -0.74 -0.4106 -0.5411 1439611 CBMicro_026405 COc1cccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I08 compound treatment 0.369 0.0119 0.99 0.358 0.00963 0.85 1.3044 0.9972 1150996 CBMicro_026406 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I09 compound treatment 0.393 0.0359 2.98 0.398 0.0496 4.4 5.2199 0.9821 1938760 CBMicro_026407 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2c(Cl)cccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I10 compound treatment 0.387 0.0299 2.49 0.399 0.0506 4.49 4.9304 0.9612 1742897 CBMicro_026408 CCN(CC)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I11 compound treatment 0.362 0.00494 0.41 0.357 0.00863 0.77 0.8309 0.9572 1938761 CBMicro_026409 Oc1ccccc1/C=N/n2c(S)nnc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I12 compound treatment 0.34 -0.0171 -1.42 0.357 0.00863 0.77 -0.4606 -0.2861 1938762 CBMicro_026410 COc1cccc(/C=N/n2c(S)nnc2c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I13 compound treatment 0.4 0.0429 3.56 0.416 0.0676 5.99 6.7588 0.9692 1938763 CBMicro_026411 Clc1ccc(cc1)c2ccc(/C=C/C(=O)c3ccccc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I14 compound treatment 0.392 0.0349 2.9 0.38 0.0316 2.8 4.0333 0.9999 1938764 CBMicro_026412 Cc1cccc(c1)N2C(=O)/C(=C/c3ccccc3[N+](=O)[O-])/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I15 compound treatment 0.587 0.23 19.09 0.503 0.155 13.7 23.1882 0.9868 1938765 CBMicro_026413 CN1C(=O)/C(=N\Nc2ccccn2)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I16 compound treatment 0.362 0.00494 0.41 0.347 -0.00137 -0.12 0.2042 0.4778 1938766 CBMicro_026414 COC(=O)CSc1nc(C)cc(C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I17 compound treatment 0.361 0.00394 0.33 0.359 0.0106 0.94 0.8975 0.8998 1445039 CBMicro_026415 OC(=O)c1ccc(cc1)S(=O)(=O)n2cnc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I18 compound treatment 0.362 0.00494 0.41 0.357 0.00863 0.77 0.8309 0.9572 1938767 CBMicro_026416 CCc1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I19 compound treatment 0.36 0.00294 0.24 0.354 0.00563 0.5 0.5255 0.9457 1938768 CBMicro_026417 CCOc1ccccc1NC(=O)C(=O)NCCOC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I20 compound treatment 0.36 0.00294 0.24 0.361 0.0126 1.12 0.9641 0.8414 1938769 CBMicro_026418 S=C1NC(=NCN1c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I21 compound treatment 0.374 0.0169 1.41 0.357 0.00863 0.77 1.5353 0.9591 1938770 CBMicro_026419 Fc1ccc2NC(=O)/C(=N\Nc3ccccn3)/c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I22 compound treatment 0.364 0.00694 0.58 0.352 0.00363 0.32 0.6349 0.9623 1660143 CBMicro_026420 OC(=O)Cn1nnc(n1)c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I23 positive control 0.089 -0.268 -22.25 0.087 -0.261 -23.16 -32.1147 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 I24 positive control 0.089 -0.268 -22.25 0.093 -0.255 -22.63 -31.7387 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J01 mock treatment 0.361 0.00394 0.33 0.344 -0.00437 -0.39 -0.0425 -0.0839 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J02 mock treatment 0.357 -6.25E-5 -0.01 0.357 0.00863 0.77 0.5373 0.7023 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J03 compound treatment 0.361 0.00394 0.33 0.319 -0.0294 -2.6 -1.6091 -0.6135 1938771 CBMicro_026421 [O-][N+](=O)c1ccc(CSCCC(=O)OCC(=O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J04 compound treatment 0.368 0.0109 0.91 0.358 0.00963 0.85 1.2457 0.9995 1938772 CBMicro_026422 COCCNC(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J05 compound treatment 0.377 0.0199 1.66 0.375 0.0266 2.36 2.8394 0.9849 1228957 CBMicro_026423 Cc1cc(C)cc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J06 compound treatment 0.367 0.00994 0.83 0.342 -0.00637 -0.56 0.1844 0.1845 1938773 CBMicro_026424 COc1ccc(cc1Cl)N(CC(=O)N/N=C(\C)/c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J07 compound treatment 0.343 -0.0141 -1.17 0.364 0.0156 1.39 0.1542 0.0851 1459251 CBMicro_026425 COc1ccc(cc1)c2nc(=S)c3CCCCc3n2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J08 compound treatment 0.36 0.00294 0.24 0.358 0.00963 0.85 0.7761 0.8741 1357916 CBMicro_026426 COc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J09 compound treatment 0.379 0.0219 1.82 0.375 0.0266 2.36 2.9568 0.9918 1130670 CBMicro_026427 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J10 compound treatment 0.363 0.00594 0.49 0.32 -0.0284 -2.51 -1.4291 -0.5578 1938774 CBMicro_026428 O=C(N1N=C(CC1c2ccccc2)c3ccccc3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J11 compound treatment 0.408 0.0509 4.23 0.396 0.0476 4.22 5.9751 1.0 1938775 CBMicro_026429 COc1cccc(NC(=O)CCN2C(=O)/C(=C/c3ccc(C)cc3)/SC2=S)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J12 compound treatment 0.365 0.00794 0.66 0.351 0.00263 0.23 0.631 0.9026 1938776 CBMicro_026430 C1SCC1Oc2ccc(/C=N/n3cnnc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J13 compound treatment 0.359 0.00194 0.16 0.359 0.0106 0.94 0.7801 0.816 1938777 CBMicro_026431 COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)NCCO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J14 compound treatment 0.366 0.00894 0.74 0.365 0.0166 1.47 1.567 0.9495 1938778 CBMicro_026432 O=C/1/C(=C/c2cccnc2)/CN(Cc3ccccc3)C\C1=C\c4cccnc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J15 compound treatment 0.345 -0.0121 -1.0 0.352 0.00363 0.32 -0.4804 -0.4567 1258015 CBMicro_026433 CCOC(=O)Cc1csc(NC(=O)c2ccco2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J16 compound treatment 0.36 0.00294 0.24 0.352 0.00363 0.32 0.4001 0.9906 1278424 CBMicro_026434 CC1(C2C(C3c4ccccc41)C(=O)N(CCO)C2=O)c5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J17 compound treatment 0.392 0.0349 2.9 0.416 0.0676 5.99 6.2892 0.9445 1297215 CBMicro_026435 Clc1ccc(Cc2cnc(NC(=O)Cc3ccccc3)s2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J18 compound treatment 0.381 0.0239 1.99 0.352 0.00363 0.32 1.6329 0.8111 1938779 CBMicro_026436 Cc1ccccc1OCCSc2ncnc3[nH]cnc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J19 compound treatment 0.362 0.00494 0.41 0.357 0.00863 0.77 0.8309 0.9572 1715378 CBMicro_026437 Cc1ccc(cc1)N2CC(CC2=O)C(=O)NCC3CCCO3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J20 compound treatment 0.358 9.37E-4 0.08 0.362 0.0136 1.21 0.9094 0.7511 1938780 CBMicro_026438 COc1ccccc1NC(=O)C(=O)N/N=C\2/C(=O)N(CC(=O)Nc3ccccc3)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J21 compound treatment 0.362 0.00494 0.41 0.363 0.0146 1.3 1.2068 0.8873 1938781 CBMicro_026439 Cc1ccccc1OCC(=O)NNC(=O)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J22 compound treatment 0.352 -0.00506 -0.42 0.318 -0.0304 -2.69 -2.2001 -0.8077 1938782 CBMicro_026440 Clc1cc(Cl)c(NNC(=O)c2cccs2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J23 positive control 0.087 -0.27 -22.42 0.087 -0.261 -23.16 -32.2321 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 J24 positive control 0.088 -0.269 -22.34 0.092 -0.256 -22.72 -31.8601 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K01 mock treatment 0.354 -0.00306 -0.25 0.356 0.00763 0.68 0.2986 0.4131 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K02 mock treatment 0.35 -0.00706 -0.59 0.35 0.00163 0.14 -0.3122 -0.517 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K03 compound treatment 0.352 -0.00506 -0.42 0.347 -0.00137 -0.12 -0.3828 -0.8753 1938783 CBMicro_026441 Sc1nnc(c2ccccc2)n1/N=C/c3ccc(o3)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K04 compound treatment 0.362 0.00494 0.41 0.35 0.00163 0.14 0.3922 0.9022 1656083 CBMicro_026442 Brc1ccc(OCC(=O)Nc2ccc(cc2)c3nc4ccccc4s3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K05 compound treatment 0.36 0.00294 0.24 0.356 0.00763 0.68 0.6508 0.905 1325266 CBMicro_026443 CCN(CC)c1ccc(NC(=O)COc2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K06 compound treatment 0.362 0.00494 0.41 0.356 0.00763 0.68 0.7682 0.9712 1230057 CBMicro_026444 CS(=O)(=O)N(CC(=O)N1CCOCC1)c2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K07 compound treatment 0.456 0.0989 8.21 0.442 0.0936 8.3 11.6755 1.0 1938784 CBMicro_026445 OC(=O)C(Cc1ccccc1)N2C(=O)/C(=C/c3ccc(Cl)cc3Cl)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K08 compound treatment 0.374 0.0169 1.41 0.373 0.0246 2.18 2.5379 0.9774 1938785 CBMicro_026446 [O-][N+](=O)c1cccc(c1)N(Cc2ccccc2)C(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K09 compound treatment 0.356 -0.00106 -0.09 0.353 0.00463 0.41 0.228 0.5428 1311611 CBMicro_026447 COC(=O)c1ccccc1NC(=O)C2CN(C3CCCCC3)C(=O)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K10 compound treatment 0.449 0.0919 7.63 0.454 0.106 9.36 12.0166 0.9949 1938786 CBMicro_026448 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2ccccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K11 compound treatment 0.396 0.0389 3.23 0.401 0.0526 4.66 5.584 0.984 1938787 CBMicro_026449 COc1ccc(OC)c(NC(=O)/C=C/c2cc(OC)ccc2OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K12 compound treatment 0.365 0.00794 0.66 0.365 0.0166 1.47 1.5083 0.9341 1699391 CBMicro_026450 CCN(CC)c1ccc(NC(=O)COc2cc(C)c(Cl)c(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K13 compound treatment 0.394 0.0369 3.07 0.39 0.0416 3.69 4.7773 0.9958 1938788 CBMicro_026451 COc1cccc(/C=C/2\SC(=O)N(CCC(=O)NNC(=O)c3cccc(Cl)c3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K14 compound treatment 0.346 -0.0111 -0.92 0.347 -0.00137 -0.12 -0.735 -0.7935 1938789 CBMicro_026452 C/C(=N\NC(=O)c1ccc(Cl)c(Cl)c1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K15 compound treatment 0.317 -0.0401 -3.33 0.362 0.0136 1.21 -1.4975 -0.4232 1938790 CBMicro_026453 Clc1ccc(OCC(=O)NNC(=O)CN2C(=O)/C(=C/c3ccc(Cl)cc3Cl)/SC2=S)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K16 compound treatment 0.351 -0.00606 -0.5 0.36 0.0116 1.03 0.3731 0.3252 1938791 CBMicro_026454 CCOC(=O)/C=C(\C)/N1N=C(CC1c2ccccc2[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K17 compound treatment 0.37 0.0129 1.07 0.364 0.0156 1.39 1.7391 0.9921 1938792 CBMicro_026455 CN1C(=O)C2(OCCO2)c3cc(ccc13)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K18 compound treatment 0.371 0.0139 1.16 0.374 0.0256 2.27 2.4245 0.951 1317443 CBMicro_026456 COc1ccc(cc1NS(=O)(=O)c2ccc(cc2)C(C)(C)C)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K19 compound treatment 0.355 -0.00206 -0.17 0.353 0.00463 0.41 0.1693 0.3805 1249483 CBMicro_026457 Clc1ccccc1C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K20 compound treatment 0.461 0.104 8.63 0.462 0.114 10.07 13.2223 0.997 1938793 CBMicro_026458 Nc1nonc1N/N=C/c2ccc3nsnc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K21 compound treatment 0.354 -0.00306 -0.25 0.349 6.33E-4 0.06 -0.1401 -0.5381 1309647 CBMicro_026459 Cc1cccc(NC(=O)C2CC=CCC2C(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K22 compound treatment 0.355 -0.00206 -0.17 0.351 0.00263 0.23 0.0439 0.1518 1277054 CBMicro_026460 O=C(COc1ccccc1)Nc2nnc(Cc3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K23 positive control 0.089 -0.268 -22.25 0.086 -0.262 -23.25 -32.1774 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 K24 positive control 0.088 -0.269 -22.34 0.095 -0.253 -22.45 -31.6721 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L01 mock treatment 0.359 0.00194 0.16 0.347 -0.00137 -0.12 0.0281 0.1395 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L02 mock treatment 0.359 0.00194 0.16 0.356 0.00763 0.68 0.5921 0.8515 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L03 compound treatment 0.361 0.00394 0.33 0.351 0.00263 0.23 0.3962 0.9864 1938794 CBMicro_026461 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(OC)ccc3OC)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L04 compound treatment 0.359 0.00194 0.16 0.352 0.00363 0.32 0.3414 0.9486 1779068 CBMicro_026462 [O-][N+](=O)c1cccc(c1)N2C(=O)C3C4C=CC(C3C2=O)C4=C5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L05 compound treatment 0.354 -0.00306 -0.25 0.354 0.00563 0.5 0.1732 0.3092 1316080 CBMicro_026463 COc1ccc(Cc2cnc(NC(=O)c3ccccc3Cl)s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L06 compound treatment 0.36 0.00294 0.24 0.354 0.00563 0.5 0.5255 0.9457 1938795 CBMicro_026464 COc1ccc(CC(=O)NNC(=O)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L07 compound treatment 0.362 0.00494 0.41 0.354 0.00563 0.5 0.6429 0.9952 1468413 CBMicro_026465 Brc1ccccc1C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L08 compound treatment 0.354 -0.00306 -0.25 0.355 0.00663 0.59 0.2359 0.3683 1688863 CBMicro_026466 O=S(=O)(N1CCCC1)c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L09 compound treatment 0.433 0.0759 6.3 0.426 0.0776 6.88 9.3227 0.999 1938796 CBMicro_026467 COc1ccc(OC)c(/C=C\2/SC(=S)N(C2=O)c3ccccc3OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L10 compound treatment 0.388 0.0309 2.57 0.371 0.0226 2.01 3.2345 0.9925 1938797 CBMicro_026468 [O-][N+](=O)c1ccccc1NC(=O)C2C(c3ccccc3)C2(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L11 compound treatment 0.395 0.0379 3.15 0.388 0.0396 3.51 4.7107 0.9985 1938798 CBMicro_026469 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)N/N=C/2\C(=O)Nc3ccccc23)c4cc(C)cc(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L12 compound treatment 0.37 0.0129 1.07 0.368 0.0196 1.74 1.9898 0.9731 1471256 CBMicro_026470 CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)c4ccccc4C3=O)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L13 compound treatment 0.358 9.37E-4 0.08 0.359 0.0106 0.94 0.7214 0.7629 1938799 CBMicro_026471 COc1ccc(NC(=O)C(=O)NCC2CCCO2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L14 compound treatment 0.359 0.00194 0.16 0.349 6.33E-4 0.06 0.1534 0.9006 1938800 CBMicro_026472 C/C(=N\NC(=O)c1ccc(Br)cc1)/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L15 compound treatment 0.363 0.00594 0.49 0.352 0.00363 0.32 0.5762 0.9787 1229704 CBMicro_026473 O=C(COc1ccccc1)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L16 compound treatment 0.36 0.00294 0.24 0.355 0.00663 0.59 0.5881 0.9241 1395937 CBMicro_026474 O=C(NCc1cccnc1)C2CCC(=O)N2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L17 compound treatment 0.362 0.00494 0.41 0.36 0.0116 1.03 1.0189 0.9183 1938801 CBMicro_026475 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(o4)[N+](=O)[O-])C(=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L18 compound treatment 0.363 0.00594 0.49 0.365 0.0166 1.47 1.3909 0.8949 1717725 CBMicro_026476 CCOC(=O)c1cccc(NC(=O)C(C)Oc2ccc(Cl)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L19 compound treatment 0.352 -0.00506 -0.42 0.356 0.00763 0.68 0.1812 0.2275 1284268 CBMicro_026477 O=C(NCc1ccco1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L20 compound treatment 0.365 0.00794 0.66 0.367 0.0186 1.65 1.6336 0.9188 1938802 CBMicro_026478 OC(=O)CN1C(=O)/C(=C/c2c(Cl)cccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L21 compound treatment 0.363 0.00594 0.49 0.354 0.00563 0.5 0.7016 1.0 1376845 CBMicro_026479 Oc1cccc(c1)N2C(=O)CSC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L22 compound treatment 0.354 -0.00306 -0.25 0.355 0.00663 0.59 0.2359 0.3683 1395470 CBMicro_026480 Cc1ccc(C)c(c1)N2C(=O)C3C4C=CC(C3C2=O)C54CC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L23 positive control 0.088 -0.269 -22.34 0.087 -0.261 -23.16 -32.1734 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 L24 positive control 0.089 -0.268 -22.25 0.093 -0.255 -22.63 -31.7387 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M01 mock treatment 0.357 -6.25E-5 -0.01 0.346 -0.00237 -0.21 -0.152 -0.7244 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M02 mock treatment 0.351 -0.00606 -0.5 0.349 6.33E-4 0.06 -0.3162 -0.6244 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M03 compound treatment 0.351 -0.00606 -0.5 0.343 -0.00537 -0.48 -0.6922 -0.9996 1675419 CBMicro_026481 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M04 compound treatment 0.36 0.00294 0.24 0.352 0.00363 0.32 0.4001 0.9906 1938803 CBMicro_026482 Cc1ccc(cc1)C2=NC(=O)/C(=C/c3ccc4OCOc4c3)/S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M05 compound treatment 0.351 -0.00606 -0.5 0.354 0.00563 0.5 -0.0029 -0.0041 1938804 CBMicro_026483 CN(C)S(=O)(=O)c1ccc(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M06 compound treatment 0.354 -0.00306 -0.25 0.359 0.0106 0.94 0.4866 0.4985 1938805 CBMicro_026484 C/C=C/COC(=O)C1=C(C)NC(=O)NC1c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M07 compound treatment 0.363 0.00594 0.49 0.354 0.00563 0.5 0.7016 1.0 1938806 CBMicro_026485 Fc1ccc(cc1)C2=NN(C(C2)c3ccco3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M08 compound treatment 0.371 0.0139 1.16 0.36 0.0116 1.03 1.5472 0.9983 1938807 CBMicro_026486 CN(C)c1ccc(/C=C(\C#N)/c2nc(cs2)c3ccc4OCOc4c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M09 compound treatment 0.363 0.00594 0.49 0.358 0.00963 0.85 0.9522 0.9659 1712755 CBMicro_026487 CCSc1nnc-2c(OC(C)(C)Nc3ccccc32)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M10 compound treatment 0.435 0.0779 6.47 0.471 0.123 10.87 12.26 0.9693 1938808 CBMicro_026488 CC/1=NN(C(=O)\C1=C/Nc2ccc(O)cc2C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M11 compound treatment 0.361 0.00394 0.33 0.354 0.00563 0.5 0.5842 0.9789 1938809 CBMicro_026489 Cc1ccc(/C=C/2\SC(=O)N(CCC(=O)Nc3ccccc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M12 compound treatment 0.379 0.0219 1.82 0.372 0.0236 2.09 2.7688 0.9976 1175572 CBMicro_026490 COc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M13 compound treatment 0.428 0.0709 5.89 0.44 0.0916 8.12 9.9065 0.9876 1938810 CBMicro_026491 COc1cc(/C=N/NC(=O)/C(=C\C=C\c2ccccc2)/NC(=O)c3ccccc3)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M14 compound treatment 0.366 0.00894 0.74 0.367 0.0186 1.65 1.6923 0.9348 1938811 CBMicro_026492 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3ccc4OCOc4c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M15 compound treatment 0.35 -0.00706 -0.59 0.352 0.00363 0.32 -0.1869 -0.2794 1418158 CBMicro_026493 C1CCC2(CC1)Nc3ccccc3NC4CCCCC42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M16 compound treatment 0.352 -0.00506 -0.42 0.353 0.00463 0.41 -0.0068 -0.0116 1938812 CBMicro_026494 COc1nccnc1NS(=O)(=O)c2ccc(N/C=C\3/C(=NN(C3=O)c4ccc(C)c(C)c4)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M17 compound treatment 0.359 0.00194 0.16 0.359 0.0106 0.94 0.7801 0.816 1938813 CBMicro_026495 COc1ccc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M18 compound treatment 0.358 9.37E-4 0.08 0.351 0.00263 0.23 0.2201 0.8945 1938814 CBMicro_026496 Cc1cc(C)nc(SCC(=O)N/N=C/c2c(Cl)cccc2Cl)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M19 compound treatment 0.427 0.0699 5.81 0.44 0.0916 8.12 9.8478 0.9865 1938815 CBMicro_026497 Cc1cccc(Nc2ccc([N+](=O)[O-])c3nonc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M20 compound treatment 0.348 -0.00906 -0.75 0.352 0.00363 0.32 -0.3043 -0.3719 1183932 CBMicro_026498 CCCCC1(CC(=C(C)CC1C(=O)O)C)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M21 compound treatment 0.356 -0.00106 -0.09 0.348 -3.67E-4 -0.03 -0.0853 -0.9079 1582070 CBMicro_026499 OC(=O)c1ccc(cc1)S(=O)(=O)NCC2CCCO2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M22 compound treatment 0.352 -0.00506 -0.42 0.351 0.00263 0.23 -0.1322 -0.2749 1476002 CBMicro_026500 CC(Oc1ccccc1)C(=O)Nc2ccc(cc2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M23 positive control 0.088 -0.269 -22.34 0.088 -0.26 -23.07 -32.1108 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 M24 positive control 0.089 -0.268 -22.25 0.095 -0.253 -22.45 -31.6134 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N01 mock treatment 0.365 0.00794 0.66 0.349 6.33E-4 0.06 0.5056 0.7646 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N02 mock treatment 0.356 -0.00106 -0.09 0.355 0.00663 0.59 0.3533 0.5944 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N03 compound treatment 0.392 0.0349 2.9 0.386 0.0376 3.34 4.4092 0.9976 1938816 CBMicro_026501 CC(=O)NN1C(=O)/C(=C\c2ccc(F)cc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N04 compound treatment 0.36 0.00294 0.24 0.35 0.00163 0.14 0.2748 0.969 1938817 CBMicro_026502 Clc1ccc(CNC=C2C(=O)NC(=O)NC2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N05 compound treatment 0.357 -6.25E-5 -0.01 0.356 0.00763 0.68 0.4747 0.7017 1568300 CBMicro_026503 CCOc1ccccc1NC(=O)CN(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N06 compound treatment 0.366 0.00894 0.74 0.362 0.0136 1.21 1.379 0.9726 1779052 CBMicro_026504 [O-][N+](=O)c1ccccc1S(=O)(=O)N(CC(=O)N2CCCCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N07 compound treatment 0.361 0.00394 0.33 0.349 6.33E-4 0.06 0.2708 0.8166 1938818 CBMicro_026505 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N08 compound treatment 0.366 0.00894 0.74 0.355 0.00663 0.59 0.9403 0.9934 1938819 CBMicro_026506 CC1(C)CC(=O)C=C(C1)Nc2ccc(F)c(F)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N09 compound treatment 0.373 0.0159 1.32 0.362 0.0136 1.21 1.7899 0.999 1606760 CBMicro_026507 Cc1ccc(NC(=O)COc2ccccc2C)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N10 compound treatment 0.36 0.00294 0.24 0.361 0.0126 1.12 0.9641 0.8414 1938820 CBMicro_026508 CCCCOc1ccc(/C=C/2\N=C(OC2=O)c3ccc(Cl)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N11 compound treatment 0.381 0.0239 1.99 0.36 0.0116 1.03 2.1342 0.9533 1938821 CBMicro_026509 [O-][N+](=O)c1ccc(NC(=O)C(=O)N/N=C\2/C(=O)N(CC(=O)Nc3ccccc3)c4ccccc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N12 compound treatment 0.396 0.0389 3.23 0.4 0.0516 4.58 5.5214 0.9855 1341059 CBMicro_026510 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2OCC)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N13 compound treatment 0.498 0.141 11.7 0.474 0.126 11.13 16.1463 0.9997 1938822 CBMicro_026511 CCOC(=O)c1c(C)c(C)sc1NC(=S)NC(=O)c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N14 compound treatment 0.4 0.0429 3.56 0.386 0.0376 3.34 4.8789 0.9994 1938823 CBMicro_026512 NS(=O)(=O)c1ccc(NC=C2C(=O)N(C3CCCCC3)C(=O)N(C4CCCCC4)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N15 compound treatment 0.356 -0.00106 -0.09 0.358 0.00963 0.85 0.5413 0.6307 1938824 CBMicro_026513 COc1ccc(OC)c(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N16 compound treatment 0.367 0.00994 0.83 0.365 0.0166 1.47 1.6257 0.9624 1207932 CBMicro_026514 CC1CC(N(C(=O)COc2ccc(Cl)cc2Cl)c3ccccc3)c4ccccc4N1C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N17 compound treatment 0.36 0.00294 0.24 0.373 0.0246 2.18 1.7161 0.7812 1293763 CBMicro_026515 Cc1cc(C)nc(SCC(=O)Nc2ccc(C)c(NC(=O)CSc3nc(C)cc(C)n3)c2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N18 compound treatment 0.365 0.00794 0.66 0.357 0.00863 0.77 1.007 0.9972 1938825 CBMicro_026516 Cc1ccc(N2CCCCC2)c3C(=O)c4ccccc4C(=O)c13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N19 compound treatment 0.363 0.00594 0.49 0.356 0.00763 0.68 0.8269 0.9879 1938826 CBMicro_026517 Cc1ccc(N2CCOCC2)c3C(=O)c4ccccc4C(=O)c13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N20 compound treatment 0.361 0.00394 0.33 0.355 0.00663 0.59 0.6468 0.9616 1938827 CBMicro_026518 CC/1=NN(C(=O)\C1=C/O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N21 compound treatment 0.374 0.0169 1.41 0.371 0.0226 2.01 2.4126 0.9849 1938828 CBMicro_026519 COc1ccc(OC)c(/C=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N22 compound treatment 0.365 0.00794 0.66 0.356 0.00763 0.68 0.9443 0.9999 1147930 CBMicro_026520 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(OC)c(OC)c2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N23 positive control 0.088 -0.269 -22.34 0.087 -0.261 -23.16 -32.1734 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 N24 positive control 0.09 -0.267 -22.17 0.094 -0.254 -22.54 -31.6174 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O01 mock treatment 0.361 0.00394 0.33 0.351 0.00263 0.23 0.3962 0.9864 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O02 mock treatment 0.353 -0.00406 -0.34 0.355 0.00663 0.59 0.1772 0.2615 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O03 compound treatment 0.357 -6.25E-5 -0.01 0.355 0.00663 0.59 0.412 0.7008 1243277 CBMicro_026521 Cc1cc(Br)cc2c1NC(=O)C32OCCO3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O04 compound treatment 0.363 0.00594 0.49 0.356 0.00763 0.68 0.8269 0.9879 1938829 CBMicro_026522 Cc1ccc(/C=C/2\SC(=S)N(NC(=O)c3cccc(c3)[N+](=O)[O-])C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O05 compound treatment 0.363 0.00594 0.49 0.366 0.0176 1.56 1.4535 0.8871 1938830 CBMicro_026523 Clc1cc2c(cc(=O)oc2cc1OC(=O)CCNC(=O)OCc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O06 compound treatment 0.354 -0.00306 -0.25 0.357 0.00863 0.77 0.3612 0.448 1543318 CBMicro_026524 CC1CCN(CC(O)COc2ccc(OCC(O)CN3CCC(C)CC3)cc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O07 compound treatment 0.367 0.00994 0.83 0.349 6.33E-4 0.06 0.6231 0.7535 1523547 CBMicro_026525 CCSc1nnc-2c(OC(Nc3ccccc32)c4ccc(cc4)C(=O)O)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O08 compound treatment 0.396 0.0389 3.23 0.407 0.0586 5.2 5.96 0.9739 1090042 CBMicro_026526 COc1ccc(cc1OC)C2CC(=Nc3ccccc3S2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O09 compound treatment 0.37 0.0129 1.07 0.361 0.0126 1.12 1.5511 0.9998 1938831 CBMicro_026527 CCOc1ccc(/C=C\2/SC(=S)N(C2=O)c3ccccc3OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O10 compound treatment 0.354 -0.00306 -0.25 0.354 0.00563 0.5 0.1732 0.3092 1304298 CBMicro_026528 Brc1ccc(cc1)C(=O)NCC(=O)c2ccc(cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O11 compound treatment 0.358 9.37E-4 0.08 0.353 0.00463 0.41 0.3454 0.8264 1938832 CBMicro_026529 CC(C)(C)c1ccc(cc1)C(=O)N2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O12 compound treatment 0.367 0.00994 0.83 0.353 0.00463 0.41 0.8737 0.9481 1406569 CBMicro_026530 CCSc1nnc-2c(OC(Nc3ccccc32)c4ccc(OCc5ccccc5)cc4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O13 compound treatment 0.377 0.0199 1.66 0.362 0.0136 1.21 2.0247 0.988 1938833 CBMicro_026531 Cc1c2NC(=O)/C(=N\Nc3ccccn3)/c2ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O14 compound treatment 0.362 0.00494 0.41 0.352 0.00363 0.32 0.5175 0.9929 1938834 CBMicro_026532 Cc1cccc(c1)C(=O)N/N=C/c2ccc(OC3CSC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O15 compound treatment 0.358 9.37E-4 0.08 0.361 0.0126 1.12 0.8467 0.7544 1406508 CBMicro_026533 COc1cc(cc(OC)c1OC)C(=O)N2N=C(CC2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O16 compound treatment 0.355 -0.00206 -0.17 0.353 0.00463 0.41 0.1693 0.3805 1699134 CBMicro_026534 Cc1ccc(cc1C)N(C2CS(=O)(=O)C=C2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O17 compound treatment 0.361 0.00394 0.33 0.359 0.0106 0.94 0.8975 0.8998 1498988 CBMicro_026535 COc1cc2cc(=O)n(Cc3ccccc3)c(C)c2cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O18 compound treatment 0.352 -0.00506 -0.42 0.354 0.00563 0.5 0.0558 0.0855 1938835 CBMicro_026536 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O19 compound treatment 0.354 -0.00306 -0.25 0.354 0.00563 0.5 0.1732 0.3092 1152220 CBMicro_026537 Clc1ccc(cc1)C(=O)CNC(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O20 compound treatment 0.35 -0.00706 -0.59 0.353 0.00463 0.41 -0.1242 -0.1736 1639492 CBMicro_026538 CCCNC(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O21 compound treatment 0.355 -0.00206 -0.17 0.358 0.00963 0.85 0.4826 0.5542 1148480 CBMicro_026539 CCOc1ccccc1C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O22 compound treatment 0.356 -0.00106 -0.09 0.355 0.00663 0.59 0.3533 0.5944 1137477 CBMicro_026540 O=C(NN1C(=O)C2C3C=CC(C2C1=O)C43CC4)c5ccncc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O23 positive control 0.086 -0.271 -22.5 0.088 -0.26 -23.07 -32.2282 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 O24 positive control 0.09 -0.267 -22.17 0.096 -0.252 -22.37 -31.492 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P01 mock treatment 0.364 0.00694 0.58 0.345 -0.00337 -0.3 0.1963 0.3026 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P02 mock treatment 0.358 9.37E-4 0.08 0.353 0.00463 0.41 0.3454 0.8264 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P03 compound treatment 0.358 9.37E-4 0.08 0.352 0.00363 0.32 0.2827 0.8534 1938836 CBMicro_026541 CCCOc1ccccc1NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P04 compound treatment 0.348 -0.00906 -0.75 0.34 -0.00837 -0.74 -1.0563 -1.0 1187836 CBMicro_026542 Brc1cccc(NC(=O)C2C3CCC=CCCC23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P05 compound treatment 0.342 -0.0151 -1.25 0.362 0.0136 1.21 -0.0299 -0.0172 1938837 CBMicro_026543 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccc(c4)[N+](=O)[O-])C(=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P06 compound treatment 0.35 -0.00706 -0.59 0.365 0.0166 1.47 0.6277 0.3957 1938838 CBMicro_026544 CC/1=NN(C(=O)\C1=C/NNC(=O)c2ccccc2[N+](=O)[O-])c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P07 compound treatment 0.364 0.00694 0.58 0.341 -0.00737 -0.65 -0.0544 -0.0625 1318576 CBMicro_026545 Clc1ccc(cc1)C(=O)CNC(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P08 compound treatment 0.351 -0.00606 -0.5 0.351 0.00263 0.23 -0.1909 -0.3441 1353365 CBMicro_026546 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2cc(C(=O)N)c(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P09 compound treatment 0.349 -0.00806 -0.67 0.358 0.00963 0.85 0.1304 0.1202 1055830 CBMicro_026547 OC(=O)C(C(c1ccccc1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P10 compound treatment 0.346 -0.0111 -0.92 0.357 0.00863 0.77 -0.1084 -0.0907 1220795 CBMicro_026548 COC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P11 compound treatment 0.35 -0.00706 -0.59 0.35 0.00163 0.14 -0.3122 -0.517 1719296 CBMicro_026549 CS(=O)(=O)N(CC(=O)Nc1cccnc1)c2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P12 compound treatment 0.353 -0.00406 -0.34 0.352 0.00363 0.32 -0.0108 -0.0232 1938839 CBMicro_026550 C/C(=N\NC(=O)c1cccc(Br)c1)/c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P13 compound treatment 0.366 0.00894 0.74 0.362 0.0136 1.21 1.379 0.9726 1938840 CBMicro_026551 Cc1ccc(cc1)N2NC(=O)/C(=C/c3ccc(cc3)N4CCOCC4)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P14 compound treatment 0.364 0.00694 0.58 0.36 0.0116 1.03 1.1363 0.9622 1448827 CBMicro_026552 COC(=O)c1ccc(NC(=O)C(C)Oc2ccc(Cl)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P15 compound treatment 0.387 0.0299 2.49 0.372 0.0236 2.09 3.2384 0.9964 1938841 CBMicro_026553 CCOc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P16 compound treatment 0.357 -6.25E-5 -0.01 0.35 0.00163 0.14 0.0987 0.6813 1938842 CBMicro_026554 Clc1ccc(NC=C2C(=O)NC(=S)NC2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P17 compound treatment 0.522 0.165 13.69 0.525 0.177 15.65 20.7511 0.9978 1938843 CBMicro_026555 Oc1ccc(Cl)cc1NC=C2C(=O)NC(=S)NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P18 compound treatment 0.352 -0.00506 -0.42 0.344 -0.00437 -0.39 -0.5708 -0.9992 1612455 CBMicro_026556 COC(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P19 compound treatment 0.344 -0.0131 -1.08 0.352 0.00363 0.32 -0.5391 -0.4766 1361258 CBMicro_026557 CN(C)c1ccc(NC(=O)COc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P20 compound treatment 0.379 0.0219 1.82 0.381 0.0326 2.89 3.3328 0.9752 1938844 CBMicro_026558 COc1cc(O)cc(Br)c1/C=N/Nc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P21 compound treatment 0.348 -0.00906 -0.75 0.351 0.00263 0.23 -0.367 -0.4659 1270527 CBMicro_026559 CN(C)CC(Oc1ccc(Cl)cc1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P22 compound treatment 0.348 -0.00906 -0.75 0.357 0.00863 0.77 0.009 0.0084 1327824 CBMicro_026560 Cc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)c3ccccc3C(=O)NCc4cccnc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P23 positive control 0.086 -0.271 -22.5 0.089 -0.259 -22.99 -32.1655 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.768 P24 positive control 0.09 -0.267 -22.17 0.093 -0.255 -22.63 -31.68 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A01 mock treatment 0.33 -0.0163 -1.36 0.328 -0.0191 -1.69 -2.153 -0.994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A02 mock treatment 0.332 -0.0143 -1.19 0.332 -0.0151 -1.34 -1.7849 -0.9983 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A03 compound treatment 0.337 -0.00932 -0.77 0.338 -0.00907 -0.8 -1.1154 -0.9998 1296973 CBMicro_026561 CCN(CC)c1ccc(NC(=O)c2cccs2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A04 compound treatment 0.338 -0.00832 -0.69 0.338 -0.00907 -0.8 -1.0567 -0.9972 1938845 CBMicro_026562 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(C)c3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A05 compound treatment 0.337 -0.00932 -0.77 0.336 -0.0111 -0.98 -1.2408 -0.9931 1938846 CBMicro_026563 CC(C)c1ccc(/N=C/c2ccc(OC3CSC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A06 compound treatment 0.336 -0.0103 -0.86 0.337 -0.0101 -0.89 -1.2368 -0.9998 1241766 CBMicro_026564 COc1cc(NC(=O)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A07 compound treatment 0.333 -0.0133 -1.11 0.34 -0.00707 -0.63 -1.2249 -0.9637 1938847 CBMicro_026565 O=C1C2C3CC(C=C3)C2C(=O)N1c4ncccn4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A08 compound treatment 0.342 -0.00432 -0.36 0.345 -0.00207 -0.18 -0.3833 -0.9513 1938848 CBMicro_026566 CN(c1c(cc(NC(=O)C)c2ccccc12)[N+](=O)[O-])S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A09 compound treatment 0.333 -0.0133 -1.11 0.334 -0.0131 -1.16 -1.6009 -0.9997 1938849 CBMicro_026567 CCOC(=O)/C(=C(\C=C\N(C)C)/N(C)C)/C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A10 compound treatment 0.333 -0.0133 -1.11 0.336 -0.0111 -0.98 -1.4756 -0.9982 1333992 CBMicro_026568 Clc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A11 compound treatment 0.378 0.0317 2.63 0.373 0.0259 2.3 3.4847 0.9977 1938850 CBMicro_026569 Cc1ccc(cc1)N2NC(=O)/C(=C/c3c[nH]c4ccccc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A12 compound treatment 0.333 -0.0133 -1.11 0.337 -0.0101 -0.89 -1.4129 -0.9943 1938851 CBMicro_026570 [O-][N+](=O)c1ccc(cc1)C(=O)N/N=C\2/C(=O)N(CC(=O)Nc3ccccc3)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A13 compound treatment 0.342 -0.00432 -0.36 0.34 -0.00707 -0.63 -0.6966 -0.9651 1938852 CBMicro_026571 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c4ccc(C)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A14 compound treatment 0.34 -0.00632 -0.52 0.336 -0.0111 -0.98 -1.0647 -0.9571 1938853 CBMicro_026572 Cc1cc(C)nc(SCC(=O)NN=C2CCCCCC2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A15 compound treatment 0.338 -0.00832 -0.69 0.337 -0.0101 -0.89 -1.1194 -0.992 1627565 CBMicro_026573 C=CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A16 compound treatment 0.362 0.0157 1.3 0.346 -0.00107 -0.09 0.8535 0.654 1228185 CBMicro_026574 CCOC(=O)c1ccc2[nH]c3C(=O)CCCCc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A17 compound treatment 0.345 -0.00132 -0.11 0.34 -0.00707 -0.63 -0.5205 -0.8186 1938854 CBMicro_026575 COC(=O)C(Cc1ccc(O)cc1)/N=C/c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A18 compound treatment 0.335 -0.0113 -0.94 0.336 -0.0111 -0.98 -1.3582 -0.9998 1938855 CBMicro_026576 COc1ccc(cc1)N(C(C)C(=O)N/N=C/c2cccnc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A19 compound treatment 0.339 -0.00732 -0.61 0.336 -0.0111 -0.98 -1.1234 -0.9735 1938856 CBMicro_026577 [O-][N+](=O)c1ccccc1C(=O)N/N=C\2/C(=O)N(Cc3ccccc3)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A20 compound treatment 0.333 -0.0133 -1.11 0.335 -0.0121 -1.07 -1.5382 -0.9999 1247898 CBMicro_026578 Cc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)c3ccccc3C(=O)NC4CCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A21 compound treatment 0.326 -0.0203 -1.69 0.324 -0.0231 -2.04 -2.6385 -0.9955 1317998 CBMicro_026579 CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3c(C)cccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A22 compound treatment 0.338 -0.00832 -0.69 0.33 -0.0171 -1.51 -1.558 -0.937 1938857 CBMicro_026580 Clc1ccc(C(=O)N/N=C/2\C(=O)Nc3ccc(Br)cc23)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A23 positive control 0.083 -0.263 -21.86 0.085 -0.262 -23.22 -31.8803 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 A24 positive control 0.084 -0.262 -21.78 0.088 -0.259 -22.96 -31.6336 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B01 mock treatment 0.342 -0.00432 -0.36 0.342 -0.00507 -0.45 -0.5713 -0.9938 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B02 mock treatment 0.349 0.00268 0.22 0.343 -0.00407 -0.36 -0.0977 -0.2307 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B03 compound treatment 0.349 0.00268 0.22 0.351 0.00393 0.35 0.4037 0.9764 1403663 CBMicro_026581 Cc1nnc(NC(=O)COc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B04 compound treatment 0.353 0.00668 0.55 0.349 0.00193 0.17 0.5131 0.8844 1710552 CBMicro_026582 COC(=O)c1cc(NC(=O)C(C)Oc2ccccc2)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B05 compound treatment 0.376 0.0297 2.46 0.389 0.0419 3.72 4.3699 0.9801 1938858 CBMicro_026583 COc1cc(ccc1O)C(=O)N/N=C/c2cc(Cl)ccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B06 compound treatment 0.348 0.00168 0.14 0.347 -6.67E-5 -0.01 0.0943 0.6765 1600781 CBMicro_026584 Cc1ccc(C)c(NC(=O)C2C3CCC=CCCC23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B07 compound treatment 0.35 0.00368 0.31 0.349 0.00193 0.17 0.337 0.9627 1938859 CBMicro_026585 O=C(Nc1nnc(CCOCCc2nnc(NC(=O)c3cccs3)s2)s1)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B08 compound treatment 0.351 0.00468 0.39 0.351 0.00393 0.35 0.5211 0.9985 1938860 CBMicro_026586 COc1ccc(/C=C/C(=O)n2nnc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B09 compound treatment 0.364 0.0177 1.47 0.362 0.0149 1.32 1.9735 0.9987 1938861 CBMicro_026587 NC1=C(Nc2ccccc2)C(=O)c3ccccc3C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B10 compound treatment 0.351 0.00468 0.39 0.349 0.00193 0.17 0.3957 0.9324 1938862 CBMicro_026588 COc1ccc(cc1)c2cc(NC=C(C(=O)C)C(=O)C)n(n2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B11 compound treatment 0.359 0.0127 1.05 0.349 0.00193 0.17 0.8654 0.8115 1938863 CBMicro_026589 CC(=O)c1cnc2c(c(C)nn2c1C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B12 compound treatment 0.347 6.77E-4 0.06 0.346 -0.00107 -0.09 -0.0271 -0.2462 1938864 CBMicro_026590 Cc1onc(c1C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B13 compound treatment 0.348 0.00168 0.14 0.349 0.00193 0.17 0.2196 0.9947 1938865 CBMicro_026591 Clc1cccc(CSCC(=O)N/N=C/c2ccc(OCC(=O)N3CCCCC3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B14 compound treatment 0.347 6.77E-4 0.06 0.351 0.00393 0.35 0.2862 0.8107 1319222 CBMicro_026592 CC(=C1C(=O)CC(C)(C)CC1=O)NCCN2CCNCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B15 compound treatment 0.349 0.00268 0.22 0.345 -0.00207 -0.18 0.0277 0.0961 1142113 CBMicro_026593 Cc1c(NC(=S)NCCc2ccccc2)c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B16 compound treatment 0.352 0.00568 0.47 0.348 9.33E-4 0.08 0.3918 0.8187 1129589 CBMicro_026594 Oc1c(Br)cc(Br)cc1C(=O)Nc2ccc(cc2Cl)C(=O)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B17 compound treatment 0.346 -3.23E-4 -0.03 0.351 0.00393 0.35 0.2275 0.6509 1938866 CBMicro_026595 O=C(CSc1ncccn1)NN=C2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B18 compound treatment 0.349 0.00268 0.22 0.345 -0.00207 -0.18 0.0277 0.0961 1938867 CBMicro_026596 [O-][N+](=O)c1cccc(c1)S(=O)(=O)N2CC(=O)NC(=O)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B19 compound treatment 0.346 -3.23E-4 -0.03 0.345 -0.00207 -0.18 -0.1484 -0.802 1938868 CBMicro_026597 Cc1cc(C)nc(SCC(=O)N/N=C/c2ccc(cc2)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B20 compound treatment 0.361 0.0147 1.22 0.36 0.0129 1.15 1.6721 0.9995 1938869 CBMicro_026598 COC(=O)c1ccc(/C=N/Nc2nc(C)c(C)s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B21 compound treatment 0.349 0.00268 0.22 0.349 0.00193 0.17 0.2783 0.9917 1938870 CBMicro_026599 C/C(=N\NC(=O)c1cccc(Br)c1)/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B22 compound treatment 0.345 -0.00132 -0.11 0.347 -6.67E-5 -0.01 -0.0818 -0.7441 1938871 CBMicro_026600 COc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)N/N=C/c3ccncc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B23 positive control 0.082 -0.264 -21.94 0.084 -0.263 -23.31 -32.0017 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 B24 positive control 0.085 -0.261 -21.69 0.085 -0.262 -23.22 -31.7629 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C01 mock treatment 0.351 0.00468 0.39 0.347 -6.67E-5 -0.01 0.2704 0.6963 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C02 mock treatment 0.36 0.0137 1.14 0.35 0.00293 0.26 0.9867 0.8471 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C03 compound treatment 0.332 -0.0143 -1.19 0.352 0.00493 0.44 -0.5316 -0.4196 1550939 CBMicro_026601 Cc1ccc2[nH]c(nc2c1)c3nonc3N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C04 compound treatment 0.356 0.00968 0.8 0.362 0.0149 1.32 1.5039 0.9714 1938872 CBMicro_026602 Cc1cc(C)nc(SCC(=O)NC(C)(C)C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C05 compound treatment 0.38 0.0337 2.8 0.372 0.0249 2.21 3.5394 0.9932 1938873 CBMicro_026603 COc1cc(ccc1O)c2nc3cc(Br)c(C)nc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C06 compound treatment 0.33 -0.0163 -1.36 0.342 -0.00507 -0.45 -1.2757 -0.8936 1782661 CBMicro_026604 CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cccc(c4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C07 compound treatment 0.349 0.00268 0.22 0.352 0.00493 0.44 0.4663 0.9508 1938874 CBMicro_026605 Oc1ccc(cc1)C(=O)NN2C(=O)C3CCCCC3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C08 compound treatment 0.354 0.00768 0.64 0.353 0.00593 0.53 0.8225 0.9954 1627956 CBMicro_026606 Ic1ccccc1C(=O)Nc2nnc(s2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C09 compound treatment 0.152 -0.194 -16.13 0.142 -0.205 -18.17 -24.2579 -0.9982 1070152 CBMicro_026607 COC(=O)c1ccc(cc1)N2C(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C10 compound treatment 0.349 0.00268 0.22 0.354 0.00693 0.61 0.5917 0.9055 1938875 CBMicro_026608 Clc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C11 compound treatment 0.347 6.77E-4 0.06 0.349 0.00193 0.17 0.1609 0.8924 1603539 CBMicro_026609 COC(=O)c1ccc(cc1NC(=O)c2cccs2)C(=O)Nc3cc(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C12 compound treatment 0.371 0.0247 2.05 0.373 0.0259 2.3 3.0738 0.9984 1938876 CBMicro_026610 Cc1ccc(cc1)C2=CC(=O)N(C2=O)c3cccc(c3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C13 compound treatment 0.403 0.0567 4.71 0.388 0.0409 3.63 5.8922 0.9917 1938877 CBMicro_026611 O=C(N/N=C/c1ccc(OC2CSC2)cc1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C14 compound treatment 0.354 0.00768 0.64 0.348 9.33E-4 0.08 0.5092 0.7922 1938878 CBMicro_026612 C=CCN1C(=O)/C(=N\NC(=O)c2ccc3ccccc3n2)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C15 compound treatment 0.352 0.00568 0.47 0.35 0.00293 0.26 0.5171 0.9607 1938879 CBMicro_026613 Cc1ccnc(/N=C/c2ccc(\C=N\c3cc(C)ccn3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C16 compound treatment 0.352 0.00568 0.47 0.356 0.00893 0.79 0.8931 0.9693 1938880 CBMicro_026614 Cc1ccc(cc1N2C(=O)C3C4C=CC(C3C2=O)C54CC5)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C17 compound treatment 0.35 0.00368 0.31 0.352 0.00493 0.44 0.525 0.9846 1333661 CBMicro_026615 OC(=O)CCn1c(SCCc2ccccc2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C18 compound treatment 0.35 0.00368 0.31 0.352 0.00493 0.44 0.525 0.9846 1725693 CBMicro_026616 CC(Oc1ccccc1)C(=O)Nc2cccc(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C19 compound treatment 0.364 0.0177 1.47 0.359 0.0119 1.06 1.7855 0.9871 1260441 CBMicro_026617 CC(Oc1ccccc1)C(=O)Nc2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C20 compound treatment 0.352 0.00568 0.47 0.35 0.00293 0.26 0.5171 0.9607 1938881 CBMicro_026618 Cc1cc(C)cc(OCC(=O)NNC(=O)c2c(C)cc(C)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C21 compound treatment 0.354 0.00768 0.64 0.35 0.00293 0.26 0.6345 0.9218 1501300 CBMicro_026619 COc1ccc(cc1OC)c2nnc(NC(=O)c3cccs3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C22 compound treatment 0.349 0.00268 0.22 0.348 9.33E-4 0.08 0.2157 0.9093 1721524 CBMicro_026620 CCN(CC)C(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C23 positive control 0.081 -0.265 -22.03 0.082 -0.265 -23.49 -32.1857 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 C24 positive control 0.084 -0.262 -21.78 0.087 -0.26 -23.05 -31.6963 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D01 mock treatment 0.349 0.00268 0.22 0.349 0.00193 0.17 0.2783 0.9917 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D02 mock treatment 0.353 0.00668 0.55 0.349 0.00193 0.17 0.5131 0.8844 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D03 compound treatment 0.353 0.00668 0.55 0.35 0.00293 0.26 0.5758 0.9404 1938882 CBMicro_026621 Cc1c(NC(=S)NCc2ccccc2)c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D04 compound treatment 0.348 0.00168 0.14 0.353 0.00593 0.53 0.4703 0.8646 1462589 CBMicro_026622 Clc1cccc(c1)N2C3CS(=O)(=O)CC3N(C2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D05 compound treatment 0.354 0.00768 0.64 0.348 9.33E-4 0.08 0.5092 0.7922 1938883 CBMicro_026623 Cc1cccc(c1)C(=O)N/N=C/c2ccc(OCC(=O)N3CCCCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D06 compound treatment 0.348 0.00168 0.14 0.348 9.33E-4 0.08 0.157 0.9691 1938884 CBMicro_026624 Ic1ccc(/N=C/c2ccc(OC3CSC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D07 compound treatment 0.351 0.00468 0.39 0.356 0.00893 0.79 0.8344 0.9462 1395634 CBMicro_026625 COc1ccc(Nc2nc(cs2)c3cc4cc(OC)ccc4oc3=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D08 compound treatment 0.349 0.00268 0.22 0.356 0.00893 0.79 0.717 0.8719 1423892 CBMicro_026626 COC(=O)CN(c1cccc(Cl)c1Cl)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D09 compound treatment 0.352 0.00568 0.47 0.349 0.00193 0.17 0.4544 0.9061 1938885 CBMicro_026627 CC(C)(C)c1nnc(NC(=O)c2cccs2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D10 compound treatment 0.353 0.00668 0.55 0.348 9.33E-4 0.08 0.4505 0.8037 1676728 CBMicro_026628 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(Cc5cccnc5)C2=O)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D11 compound treatment 0.361 0.0147 1.22 0.35 0.00293 0.26 1.0454 0.8391 1320466 CBMicro_026629 NC(=O)CSc1nc2ccccc2n1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D12 compound treatment 0.351 0.00468 0.39 0.348 9.33E-4 0.08 0.3331 0.8389 1938886 CBMicro_026630 CN1CCN(CC1)NC(=O)CN2C(=O)S/C(=C/c3ccccc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D13 compound treatment 0.363 0.0167 1.38 0.359 0.0119 1.06 1.7268 0.9912 1305816 CBMicro_026631 Cc1cccc(c1)C(=O)Oc2ccc3c(C)cc(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D14 compound treatment 0.354 0.00768 0.64 0.351 0.00393 0.35 0.6972 0.9597 1938887 CBMicro_026632 C/C(=N\NC(=O)CSc1ncccn1)/c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D15 compound treatment 0.355 0.00868 0.72 0.34 -0.00707 -0.63 0.0666 0.0697 1938888 CBMicro_026633 CCc1c(C)n[n+]2cnn(Cc3ccc(Cl)cc3)c2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D16 compound treatment 0.323 -0.0233 -1.94 0.338 -0.00907 -0.8 -1.9373 -0.9241 1260900 CBMicro_026634 Cc1ccc(c2csc(Nc3cccc(O)c3)n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D17 compound treatment 0.363 0.0167 1.38 0.361 0.0139 1.23 1.8522 0.9984 1332866 CBMicro_026635 Cc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)c5ccccc5C4=O)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D18 compound treatment 0.352 0.00568 0.47 0.35 0.00293 0.26 0.5171 0.9607 1938889 CBMicro_026636 CC(Sc1nc(C)cc(C)n1)C(=O)N/N=C/c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D19 compound treatment 0.35 0.00368 0.31 0.35 0.00293 0.26 0.3997 0.9968 1298377 CBMicro_026637 CC(=O)N(C1CS(=O)(=O)C=C1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D20 compound treatment 0.374 0.0277 2.3 0.37 0.0229 2.03 3.0619 0.9981 1525028 CBMicro_026638 CS(=O)(=O)N(CC(=O)Nc1cccc(Br)c1)c2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D21 compound treatment 0.354 0.00768 0.64 0.345 -0.00207 -0.18 0.3212 0.4843 1938890 CBMicro_026639 CCOC(=O)C(NC(=O)CC)C(O)c1cccc(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D22 compound treatment 0.349 0.00268 0.22 0.346 -0.00107 -0.09 0.0903 0.374 1126131 CBMicro_026640 OCCN(CCO)c1cccc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D23 positive control 0.082 -0.264 -21.94 0.082 -0.265 -23.49 -32.127 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 D24 positive control 0.085 -0.261 -21.69 0.087 -0.26 -23.05 -31.6376 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E01 mock treatment 0.343 -0.00332 -0.28 0.342 -0.00507 -0.45 -0.5125 -0.9726 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E02 mock treatment 0.355 0.00868 0.72 0.349 0.00193 0.17 0.6305 0.8515 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E03 compound treatment 0.375 0.0287 2.38 0.386 0.0389 3.45 4.1232 0.9836 1938891 CBMicro_026641 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3cccc(Br)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E04 compound treatment 0.347 6.77E-4 0.06 0.348 9.33E-4 0.08 0.0983 0.9823 1938892 CBMicro_026642 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E05 compound treatment 0.346 -3.23E-4 -0.03 0.346 -0.00107 -0.09 -0.0858 -0.8731 1938893 CBMicro_026643 O=C(NCCCN1CCOCC1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E06 compound treatment 0.345 -0.00132 -0.11 0.35 0.00293 0.26 0.1062 0.3763 1938894 CBMicro_026644 COc1cccc(NC(=O)/C=C(\C(=O)O)/c2ccc(Cl)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E07 compound treatment 0.356 0.00968 0.8 0.352 0.00493 0.44 0.8772 0.9591 1412523 CBMicro_026645 CC(C)c1ccc(OC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E08 compound treatment 0.355 0.00868 0.72 0.364 0.0169 1.5 1.5705 0.9435 1938895 CBMicro_026646 COc1ccc(cc1)N(C(C)C(=O)N/N=C/c2cccs2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E09 compound treatment 0.402 0.0557 4.62 0.392 0.0449 3.98 6.0842 0.9972 1412116 CBMicro_026647 COc1ccc(cc1Cl)N(CC(=O)Nc2ccccc2OC)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E10 compound treatment 0.357 0.0107 0.89 0.357 0.00993 0.88 1.2493 1.0 1649764 CBMicro_026648 Brc1ccc(cc1)C(=O)N2CCC(C2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E11 compound treatment 0.359 0.0127 1.05 0.357 0.00993 0.88 1.3667 0.9961 1938896 CBMicro_026649 COc1cc(ccc1OC(=O)c2ccc(cc2Cl)[N+](=O)[O-])C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E12 compound treatment 0.347 6.77E-4 0.06 0.356 0.00893 0.79 0.5996 0.7554 1709109 CBMicro_026650 CCOc1ccc2N(C(=O)CN3C(=O)c4ccccc4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E13 compound treatment 0.367 0.0207 1.72 0.371 0.0239 2.12 2.7136 0.9945 1938897 CBMicro_026651 [O-][N+](=O)c1ccc(c(c1)C(F)(F)F)n2cnc3ccccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E14 compound treatment 0.357 0.0107 0.89 0.348 9.33E-4 0.08 0.6853 0.7697 1729858 CBMicro_026652 Cc1cccc(c1)C2(CC2C(=O)N3CCCCC3)c4cccc(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E15 compound treatment 0.35 0.00368 0.31 0.368 0.0209 1.86 1.5277 0.8125 1938898 CBMicro_026653 CC(C)(C)c1ccc2[nH]c3/C(=N/O)/CCCc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E16 compound treatment 0.352 0.00568 0.47 0.346 -0.00107 -0.09 0.2664 0.5543 1779201 CBMicro_026654 Cc1cc(=O)oc2cc(OC(=O)c3ccc(cc3Cl)[N+](=O)[O-])ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E17 compound treatment 0.351 0.00468 0.39 0.343 -0.00407 -0.36 0.0197 0.0373 1938899 CBMicro_026655 Nn1cnc2scc(c3ccccc3)c2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E18 compound treatment 0.355 0.00868 0.72 0.348 9.33E-4 0.08 0.5679 0.7832 1938900 CBMicro_026656 COc1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E19 compound treatment 0.345 -0.00132 -0.11 0.342 -0.00507 -0.45 -0.3951 -0.8548 1938901 CBMicro_026657 CC/1=NN(C(=O)\C1=C/NNc2ccc(C)cc2C)c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E20 compound treatment 0.331 -0.0153 -1.27 0.351 0.00393 0.35 -0.653 -0.4951 1938902 CBMicro_026658 [O-][N+](=O)c1cc(ccc1Cl)C(=O)N/N=C/2\C(=O)N(CC=C)c3ccc(Br)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E21 compound treatment 0.356 0.00968 0.8 0.357 0.00993 0.88 1.1906 0.999 1938903 CBMicro_026659 Cc1nnc(N/N=C/c2ccc(Cl)c(c2)[N+](=O)[O-])[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E22 compound treatment 0.344 -0.00232 -0.19 0.35 0.00293 0.26 0.0475 0.1467 1938904 CBMicro_026660 [O-][N+](=O)c1ccc(C(=O)N/N=C/c2ccccn2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E23 positive control 0.083 -0.263 -21.86 0.085 -0.262 -23.22 -31.8803 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 E24 positive control 0.087 -0.259 -21.53 0.091 -0.256 -22.69 -31.2695 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F01 mock treatment 0.343 -0.00332 -0.28 0.344 -0.00307 -0.27 -0.3872 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F02 mock treatment 0.348 0.00168 0.14 0.348 9.33E-4 0.08 0.157 0.9691 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F03 compound treatment 0.352 0.00568 0.47 0.353 0.00593 0.53 0.7051 0.9985 1165528 CBMicro_026661 COC(=O)CN(c1ccc(Cl)cc1Cl)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F04 compound treatment 0.353 0.00668 0.55 0.345 -0.00207 -0.18 0.2625 0.4496 1727308 CBMicro_026662 O=C(Nc1cccc2ccccc12)N3CCCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F05 compound treatment 0.348 0.00168 0.14 0.353 0.00593 0.53 0.4703 0.8646 1360410 CBMicro_026663 COc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)c5ccccc5C4=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F06 compound treatment 0.348 0.00168 0.14 0.355 0.00793 0.7 0.5956 0.831 1648740 CBMicro_026664 CC(Oc1ccccc1)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F07 compound treatment 0.351 0.00468 0.39 0.349 0.00193 0.17 0.3957 0.9324 1938905 CBMicro_026665 CN1C(=O)N(C)C(=O)C(=CNC2CC(C)(C)NC(C)(C)C2)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F08 compound treatment 0.373 0.0267 2.21 0.382 0.0349 3.1 3.7552 0.9865 1938906 CBMicro_026666 CC(C)c1ccc(C)cc1OCC(=O)NNC(=O)/C=C/c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F09 compound treatment 0.352 0.00568 0.47 0.343 -0.00407 -0.36 0.0784 0.1322 1189643 CBMicro_026667 COc1ccc(cc1)C2NC(=S)NC3=C2N4CCC3CC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F10 compound treatment 0.355 0.00868 0.72 0.367 0.0199 1.77 1.7585 0.9218 1721317 CBMicro_026668 CCCc1ccc2c(N)c(sc2n1)C(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F11 compound treatment 0.354 0.00768 0.64 0.353 0.00593 0.53 0.8225 0.9954 1778401 CBMicro_026669 [O-][N+](=O)c1ccc(cc1)c2nnc(NC(=O)c3cccs3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F12 compound treatment 0.348 0.00168 0.14 0.35 0.00293 0.26 0.2823 0.9572 1160328 CBMicro_026670 CC1(C)CC(=O)C=C(C1)NC2CC(C)(C)NC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F13 compound treatment 0.346 -3.23E-4 -0.03 0.35 0.00293 0.26 0.1649 0.6309 1938907 CBMicro_026671 C/C(=N\NC(=O)c1ccccc1Cl)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F14 compound treatment 0.351 0.00468 0.39 0.353 0.00593 0.53 0.6464 0.9889 1188488 CBMicro_026672 COC(=O)CN(c1ccccc1C)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F15 compound treatment 0.469 0.123 10.18 0.459 0.112 9.92 14.2159 0.9999 1938908 CBMicro_026673 CCN(CC)c1ccc(/C=N/NC(=O)c2cc(Br)ccc2O)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F16 compound treatment 0.413 0.0667 5.54 0.408 0.0609 5.4 7.7326 0.9999 1938909 CBMicro_026674 COc1ccc(cc1OC)C(=O)N/N=C/c2cc(OC)c(O)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F17 compound treatment 0.37 0.0237 1.97 0.368 0.0209 1.86 2.7017 0.9996 1938910 CBMicro_026675 [O-][N+](=O)c1cccc(c1)C2=CC(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F18 compound treatment 0.365 0.0187 1.55 0.348 9.33E-4 0.08 1.1549 0.7438 1355530 CBMicro_026676 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NC2CCCCC2)c3cc(C)cc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F19 compound treatment 0.336 -0.0103 -0.86 0.354 0.00693 0.61 -0.1715 -0.1626 1338180 CBMicro_026677 CCOc1ccc(cc1)N(CC(=O)N2CCOCC2)S(=O)(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F20 compound treatment 0.394 0.0477 3.96 0.395 0.0479 4.25 5.8026 0.9994 1743124 CBMicro_026678 O=C(Nc1ccc(cc1)S(=O)c2ccc(NC(=O)c3cccs3)cc2)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F21 compound treatment 0.37 0.0237 1.97 0.374 0.0269 2.39 3.0777 0.9954 1938911 CBMicro_026679 Cc1cc(C)cc(OC(=O)COc2ccc(Br)cc2Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F22 compound treatment 0.352 0.00568 0.47 0.344 -0.00307 -0.27 0.1411 0.2594 1573803 CBMicro_026680 COc1ccc(cc1)N2C(=O)C3C4C=CC(C3C2=O)C4=C5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F23 positive control 0.085 -0.261 -21.69 0.085 -0.262 -23.22 -31.7629 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 F24 positive control 0.087 -0.259 -21.53 0.089 -0.258 -22.87 -31.3949 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G01 mock treatment 0.334 -0.0123 -1.02 0.343 -0.00407 -0.36 -0.9782 -0.9019 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G02 mock treatment 0.341 -0.00532 -0.44 0.342 -0.00507 -0.45 -0.63 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G03 compound treatment 0.348 0.00168 0.14 0.351 0.00393 0.35 0.345 0.919 1938912 CBMicro_026681 CCOc1cc(/C=N/NC(=O)CSc2nc(C)cc(C)n2)ccc1OCc3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G04 compound treatment 0.352 0.00568 0.47 0.347 -6.67E-5 -0.01 0.3291 0.6982 1592283 CBMicro_026682 CCC(=O)Nc1nnc(COc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G05 compound treatment 0.347 6.77E-4 0.06 0.344 -0.00307 -0.27 -0.1524 -0.5491 1205301 CBMicro_026683 CCCCC(=O)Nc1nnc(Cc2ccc(Cl)cc2Cl)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G06 compound treatment 0.351 0.00468 0.39 0.346 -0.00107 -0.09 0.2077 0.5198 1651359 CBMicro_026684 O=C1C2C3CC(C=C3)C2C(=O)N1CCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G07 compound treatment 0.342 -0.00432 -0.36 0.358 0.0109 0.97 0.4314 0.4175 1938913 CBMicro_026685 Clc1cccc(/N=C/c2ccc(OC3CSC3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G08 compound treatment 0.356 0.00968 0.8 0.347 -6.67E-5 -0.01 0.5639 0.7019 1284096 CBMicro_026686 OC(=O)c1cc(NS(=O)(=O)c2ccc3OCCOc3c2)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G09 compound treatment 0.35 0.00368 0.31 0.35 0.00293 0.26 0.3997 0.9968 1618576 CBMicro_026687 COc1ccc(cc1)c2cc(O)cc(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G10 compound treatment 0.357 0.0107 0.89 0.348 9.33E-4 0.08 0.6853 0.7697 1938914 CBMicro_026688 [O-][N+](=O)c1cccc(NC(=O)C(=O)N/N=C\2/C(=O)N(CC(=O)Nc3ccccc3)c4ccccc24)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G11 compound treatment 0.421 0.0747 6.2 0.431 0.0839 7.44 9.6435 0.9959 1938915 CBMicro_026689 COc1ccc(OC)c(/C=C/C(=O)Nc2ccc(cc2)N(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G12 compound treatment 0.361 0.0147 1.22 0.359 0.0119 1.06 1.6094 0.9975 1938916 CBMicro_026690 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/C=C/c3cccc(c3)[N+](=O)[O-])/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G13 compound treatment 0.348 0.00168 0.14 0.348 9.33E-4 0.08 0.157 0.9691 1938917 CBMicro_026691 CC(=O)Nc1ccc(I)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G14 compound treatment 0.445 0.0987 8.19 0.443 0.0959 8.5 11.8044 0.9998 1321113 CBMicro_026692 COc1ccc2NC(C)(C)c3sn(c4cc(C)cc(C)c4)c(=S)c3-c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G15 compound treatment 0.498 0.152 12.59 0.458 0.111 9.83 15.8556 0.9925 1938918 CBMicro_026693 O=C1NC(=S)NC(=O)C1=CNc2ccccc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G16 compound treatment 0.342 -0.00432 -0.36 0.355 0.00793 0.7 0.2434 0.3083 1248206 CBMicro_026694 COc1ccc(cc1Cl)N(CC(=O)NCc2ccco2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G17 compound treatment 0.348 0.00168 0.14 0.351 0.00393 0.35 0.345 0.919 1938919 CBMicro_026695 COc1ccc(cc1)N(C(C)C(=O)NN=C2CCN(C)CC2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G18 compound treatment 0.366 0.0197 1.63 0.361 0.0139 1.23 2.0283 0.9905 1938920 CBMicro_026696 CC/1=NN(C(=O)\C1=C/NNC(=O)c2cccc(c2)[N+](=O)[O-])c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G19 compound treatment 0.347 6.77E-4 0.06 0.353 0.00593 0.53 0.4116 0.7783 1938921 CBMicro_026697 O=c1cnnc(N/N=C/C=C/c2ccccc2)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G20 compound treatment 0.352 0.00568 0.47 0.354 0.00693 0.61 0.7678 0.9914 1387211 CBMicro_026698 CCn1c2ccccc2c3nnc(SCC(=O)N)nc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G21 compound treatment 0.356 0.00968 0.8 0.358 0.0109 0.97 1.2532 0.9957 1530627 CBMicro_026699 COc1ccc(NC(=O)CC(C)Cc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G22 compound treatment 0.346 -3.23E-4 -0.03 0.342 -0.00507 -0.45 -0.3364 -0.748 1219950 CBMicro_026700 Cc1cc(ccc1NC(=O)c2cccs2)C3CCC(CC3)c4ccc(NC(=O)c5cccs5)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G23 positive control 0.085 -0.261 -21.69 0.088 -0.259 -22.96 -31.5749 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 G24 positive control 0.09 -0.256 -21.28 0.092 -0.255 -22.6 -31.0308 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H01 mock treatment 0.339 -0.00732 -0.61 0.343 -0.00407 -0.36 -0.6847 -0.9688 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H02 mock treatment 0.346 -3.23E-4 -0.03 0.34 -0.00707 -0.63 -0.4618 -0.7367 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H03 compound treatment 0.342 -0.00432 -0.36 0.345 -0.00207 -0.18 -0.3833 -0.9513 1938922 CBMicro_026701 CCN(CC)c1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H04 compound treatment 0.349 0.00268 0.22 0.349 0.00193 0.17 0.2783 0.9917 1938923 CBMicro_026702 COC(=O)CN(c1ccc(Cl)cc1Cl)S(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H05 compound treatment 0.407 0.0607 5.04 0.404 0.0569 5.05 7.1297 1.0 1938924 CBMicro_026703 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(F)F)cc3)C(=O)CC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H06 compound treatment 0.351 0.00468 0.39 0.343 -0.00407 -0.36 0.0197 0.0373 1938925 CBMicro_026704 Cc1cccc(c1)C(=O)N2c3ccc(cc3-c4c(ssc4=S)C2(C)C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H07 compound treatment 0.353 0.00668 0.55 0.347 -6.67E-5 -0.01 0.3878 0.6995 1938926 CBMicro_026705 CCOc1ccccc1N2C(=O)C3C(C4C=CC3C5CC54)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H08 compound treatment 0.346 -3.23E-4 -0.03 0.345 -0.00207 -0.18 -0.1484 -0.802 1311133 CBMicro_026706 CCOC(=O)Cc1nnc(NC(=O)c2cccs2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H09 compound treatment 0.432 0.0857 7.11 0.393 0.0459 4.07 7.908 0.9649 1938927 CBMicro_026707 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3cc(OC)c(OC)cc3Br)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H10 compound treatment 0.35 0.00368 0.31 0.337 -0.0101 -0.89 -0.415 -0.4401 1938928 CBMicro_026708 CCOC(=O)C(NS(=O)(=O)c1ccc-2c(Cc3ccccc32)c1)C(O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H11 compound treatment 0.343 -0.00332 -0.28 0.348 9.33E-4 0.08 -0.1366 -0.4742 1233429 CBMicro_026709 COc1ccc(cc1)c2nnc(NC(=O)c3ccc(Cl)cc3Cl)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H12 compound treatment 0.341 -0.00532 -0.44 0.323 -0.0241 -2.13 -1.8206 -0.8359 1938929 CBMicro_026710 CCOC(=O)/C=C(\C)/N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H13 compound treatment 0.337 -0.00932 -0.77 0.353 0.00593 0.53 -0.1755 -0.1875 1938930 CBMicro_026711 C(=N/c1nc2ccccc2s1)\c3ccc(/C=N/c4nc5ccccc5s4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H14 compound treatment 0.344 -0.00232 -0.19 0.348 9.33E-4 0.08 -0.0779 -0.3711 1938931 CBMicro_026712 Cc1ccc(/N=C/c2ccc(OC3CSC3)cc2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H15 compound treatment 0.395 0.0487 4.04 0.389 0.0419 3.72 5.4853 0.9991 1938932 CBMicro_026713 CCc1nnc(NS(=O)(=O)c2ccc(N/C=C\3/C(=NN(C3=O)c4ccc(Cl)cc4)C)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H16 compound treatment 0.35 0.00368 0.31 0.339 -0.00807 -0.71 -0.2896 -0.3726 1938933 CBMicro_026714 Cc1ccc(cc1)N2C(=O)/C(=C/NC3CCCCC3)/c4ccccc4C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H17 compound treatment 0.345 -0.00132 -0.11 0.348 9.33E-4 0.08 -0.0192 -0.1393 1938934 CBMicro_026715 C(Cc1ccccc1)/N=C/c2ccc(OC3CSC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H18 compound treatment 0.403 0.0567 4.71 0.395 0.0479 4.25 6.3309 0.9987 1938935 CBMicro_026716 COc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)N/N=C/c3sccc3C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H19 compound treatment 0.343 -0.00332 -0.28 0.343 -0.00407 -0.36 -0.4499 -0.9913 1741729 CBMicro_026717 COC(=O)CN(c1ccc(OC)cc1OC)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H20 compound treatment 0.378 0.0317 2.63 0.378 0.0309 2.74 3.798 0.9998 1938936 CBMicro_026718 COc1cccc(/C=N/NC(=O)c2cnccn2)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H21 compound treatment 0.352 0.00568 0.47 0.348 9.33E-4 0.08 0.3918 0.8187 1938937 CBMicro_026719 CN(C)c1ccc(N/C=C\2/C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H22 compound treatment 0.346 -3.23E-4 -0.03 0.345 -0.00207 -0.18 -0.1484 -0.802 1237768 CBMicro_026720 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Br)c(=O)n2C1c5ccc(OC)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H23 positive control 0.086 -0.26 -21.61 0.086 -0.261 -23.14 -31.6416 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 H24 positive control 0.09 -0.256 -21.28 0.092 -0.255 -22.6 -31.0308 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I01 mock treatment 0.349 0.00268 0.22 0.352 0.00493 0.44 0.4663 0.9508 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I02 mock treatment 0.352 0.00568 0.47 0.352 0.00493 0.44 0.6424 0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I03 compound treatment 0.361 0.0147 1.22 0.353 0.00593 0.53 1.2334 0.9294 1938938 CBMicro_026721 COc1ccc(cc1)c2nnc(N/C=C\3/C(=NN(C3=O)c4ccc(C)c(C)c4)C)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I04 compound treatment 0.345 -0.00132 -0.11 0.342 -0.00507 -0.45 -0.3951 -0.8548 1180345 CBMicro_026722 NC(=O)c1cccc2Cc3ccccc3-c21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I05 compound treatment 0.357 0.0107 0.89 0.354 0.00693 0.61 1.0613 0.984 1938939 CBMicro_026723 C/C(=N\NC(=O)c1cc(Br)ccc1O)/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I06 compound treatment 0.368 0.0217 1.8 0.348 9.33E-4 0.08 1.331 0.7388 1352837 CBMicro_026724 CCOc1ccc2N(C(=O)CN3C(=O)c4ccccc4C3=O)C(C)(C)C=C(C)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I07 compound treatment 0.374 0.0277 2.3 0.563 0.216 19.14 15.1562 0.7864 1938940 CBMicro_026725 CCc1nnc(N/C=C\2/C(=NN(C2=O)c3ccc(C)c(C)c3)C)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I08 compound treatment 0.356 0.00968 0.8 0.357 0.00993 0.88 1.1906 0.999 1938941 CBMicro_026726 Cc1ccc(C/N=C/c2ccc(OC3CSC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I09 compound treatment 0.477 0.131 10.85 0.485 0.138 12.22 16.3148 0.9982 1938942 CBMicro_026727 COc1cc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)cc(Br)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I10 compound treatment 0.352 0.00568 0.47 0.356 0.00893 0.79 0.8931 0.9693 1516248 CBMicro_026728 COc1ccc(cc1OC)C(=O)Nc2nnc(Cc3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I11 compound treatment 0.348 0.00168 0.14 0.349 0.00193 0.17 0.2196 0.9947 1132008 CBMicro_026729 COC12CCCCC2OC3(CCCCC3O1)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I12 compound treatment 0.343 -0.00332 -0.28 0.351 0.00393 0.35 0.0514 0.1157 1083981 CBMicro_026730 Cc1cc(NC(=O)Nc2ccccc2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I13 compound treatment 0.357 0.0107 0.89 0.353 0.00593 0.53 0.9986 0.9689 1049846 CBMicro_026731 O=C(Nc1ccccc1)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I14 compound treatment 0.351 0.00468 0.39 0.356 0.00893 0.79 0.8344 0.9462 1938943 CBMicro_026732 Cc1cc(C)nc(SCC(=O)N/N=C/c2ccc(O)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I15 compound treatment 0.349 0.00268 0.22 0.349 0.00193 0.17 0.2783 0.9917 1441343 CBMicro_026733 Clc1ccc(cc1)N2C3CS(=O)(=O)CC3N(C2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I16 compound treatment 0.362 0.0157 1.3 0.353 0.00593 0.53 1.2921 0.9205 1580695 CBMicro_026734 CCn1c2ccccc2c3nnc(SCC(=O)NC(C)c4ccccc4)nc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I17 compound treatment 0.419 0.0727 6.03 0.432 0.0849 7.53 9.5888 0.994 1938944 CBMicro_026735 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccc(C)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I18 compound treatment 0.389 0.0427 3.54 0.412 0.0649 5.75 6.5744 0.9729 1674624 CBMicro_026736 COC(=O)c1ccc(cc1NC(=O)c2cc3cccc(O)c3cc2O)C(=O)Nc4cc(Cl)ccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I19 compound treatment 0.358 0.0117 0.97 0.354 0.00693 0.61 1.12 0.9758 1938945 CBMicro_026737 COc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)N/N=C/c3ccccn3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I20 compound treatment 0.351 0.00468 0.39 0.35 0.00293 0.26 0.4584 0.981 1316152 CBMicro_026738 CN1CCN(CC1)C(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I21 compound treatment 0.387 0.0407 3.38 0.395 0.0479 4.25 5.3916 0.9935 1210596 CBMicro_026739 CC(C)CC(=O)Nc1nnc(Cc2ccc(Cl)cc2Cl)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I22 compound treatment 0.349 0.00268 0.22 0.351 0.00393 0.35 0.4037 0.9764 1363125 CBMicro_026740 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N4C2c5ccccc5C4=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I23 positive control 0.084 -0.262 -21.78 0.086 -0.261 -23.14 -31.759 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 I24 positive control 0.089 -0.257 -21.36 0.093 -0.254 -22.52 -31.0268 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J01 mock treatment 0.303 -0.0433 -3.6 0.329 -0.0181 -1.6 -3.6753 -0.9336 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J02 mock treatment 0.344 -0.00232 -0.19 0.352 0.00493 0.44 0.1728 0.3616 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J03 compound treatment 0.351 0.00468 0.39 0.339 -0.00807 -0.71 -0.2309 -0.2838 1938946 CBMicro_026741 CC(=C1C2C=CC1C3C2C(=O)N(C3=O)c4cccc(Br)c4)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J04 compound treatment 0.358 0.0117 0.97 0.353 0.00593 0.53 1.0573 0.9587 1938947 CBMicro_026742 Cc1cccc(Cc2cnc(NC(=O)CCN3C(=O)/C(=C/c4ccccc4Cl)/SC3=S)s2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J05 compound treatment 0.364 0.0177 1.47 0.359 0.0119 1.06 1.7855 0.9871 1938948 CBMicro_026743 Cc1cccc(N2C(=O)/C(=C/c3ccccc3[N+](=O)[O-])/SC2=S)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J06 compound treatment 0.37 0.0237 1.97 0.352 0.00493 0.44 1.6991 0.8438 1557111 CBMicro_026744 Cc1nn(c(N2CCCCC2)c1C=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J07 compound treatment 0.34 -0.00632 -0.52 0.355 0.00793 0.7 0.126 0.1436 1175088 CBMicro_026745 CN(C)c1ccc(NC(=O)COc2cccc(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J08 compound treatment 0.356 0.00968 0.8 0.358 0.0109 0.97 1.2532 0.9957 1603593 CBMicro_026746 Fc1ccccc1C(=O)N(C2CS(=O)(=O)C=C2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J09 compound treatment 0.358 0.0117 0.97 0.366 0.0189 1.68 1.872 0.966 1938949 CBMicro_026747 CC(NC(=O)CSC(=O)c1ccccc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J10 compound treatment 0.084 -0.262 -21.78 0.083 -0.264 -23.4 -31.947 -0.9994 1938950 CBMicro_026748 Clc1cc(Cl)c(NN2C(=O)C=CC2=O)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J11 compound treatment 0.357 0.0107 0.89 0.35 0.00293 0.26 0.8106 0.8775 1938951 CBMicro_026749 Cc1cccc(NC(=O)/C=C(\C(=O)O)/c2ccc(Cl)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J12 compound treatment 0.392 0.0457 3.79 0.391 0.0439 3.89 5.4345 0.9999 1938952 CBMicro_026750 COc1ccc(/C=C\2/N3CCC(CC3)C2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J13 compound treatment 0.345 -0.00132 -0.11 0.347 -6.67E-5 -0.01 -0.0818 -0.7441 1641214 CBMicro_026751 COC(=O)CN(c1ccccc1OC)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J14 compound treatment 0.359 0.0127 1.05 0.358 0.0109 0.97 1.4293 0.9991 1938953 CBMicro_026752 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J15 compound treatment 0.385 0.0387 3.21 0.402 0.0549 4.87 5.7129 0.9796 1660963 CBMicro_026753 Clc1ccc(c2nnc(NC(=O)c3ccccc3Br)s2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J16 compound treatment 0.36 0.0137 1.14 0.349 0.00193 0.17 0.9241 0.8047 1665408 CBMicro_026754 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4ccc(OC)c(OC)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J17 compound treatment 0.386 0.0397 3.29 0.375 0.0279 2.48 4.0796 0.9901 1271662 CBMicro_026755 Clc1ccc(C(=O)Nc2nnc(s2)c3ccccc3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J18 compound treatment 0.357 0.0107 0.89 0.355 0.00793 0.7 1.1239 0.9934 1503455 CBMicro_026756 CN1CCN(CC1)C(=O)c2cc3cccc(CC=C)c3oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J19 compound treatment 0.4 0.0537 4.46 0.402 0.0549 4.87 6.5934 0.999 1938954 CBMicro_026757 CCN(CC)S(=O)(=O)c1ccc(N/C=C\2/C(=NN(C2=O)c3ccc(Cl)cc3)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J20 compound treatment 0.358 0.0117 0.97 0.344 -0.00307 -0.27 0.4933 0.49 1938955 CBMicro_026758 CC1CCCCN1C(=O)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J21 compound treatment 0.362 0.0157 1.3 0.361 0.0139 1.23 1.7934 0.9997 1479794 CBMicro_026759 OC(=O)c1ccc2C(=O)N(Nc3c(Cl)cc(Cl)cc3Cl)C(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J22 compound treatment 0.34 -0.00632 -0.52 0.358 0.0109 0.97 0.314 0.2849 1938956 CBMicro_026760 [O-][N+](=O)c1cc(C=c2sc3nc4ccccc4n3c2=O)c(cc1N5CCOCC5)N6CCOCC6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J23 positive control 0.085 -0.261 -21.69 0.086 -0.261 -23.14 -31.7003 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 J24 positive control 0.089 -0.257 -21.36 0.119 -0.228 -20.21 -29.3975 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K01 mock treatment 0.345 -0.00132 -0.11 0.349 0.00193 0.17 0.0435 0.2138 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K02 mock treatment 0.353 0.00668 0.55 0.347 -6.67E-5 -0.01 0.3878 0.6995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K03 compound treatment 0.348 0.00168 0.14 0.342 -0.00507 -0.45 -0.219 -0.4659 1938957 CBMicro_026761 C/C(=N/NC(=O)Cc1ccccc1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K04 compound treatment 0.354 0.00768 0.64 0.348 9.33E-4 0.08 0.5092 0.7922 1938958 CBMicro_026762 COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)Nc2ccc(C(=O)O)c(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K05 compound treatment 0.449 0.103 8.52 0.435 0.0879 7.79 11.5379 0.999 1938959 CBMicro_026763 Oc1ccc(/C=C/C(=O)c2ccc(NC3=C(N4CCCCC4)C(=O)c5ccccc5C3=O)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K06 compound treatment 0.357 0.0107 0.89 0.351 0.00393 0.35 0.8733 0.9168 1938960 CBMicro_026764 O=C(CN1C(=O)/C(=N/NC(=S)Nc2ccccc2)/c3ccccc13)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K07 compound treatment 0.354 0.00768 0.64 0.341 -0.00607 -0.54 0.0705 0.0846 1304431 CBMicro_026765 Cc1cc(C)nc(n1)N2C(=O)c3ccc(cc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K08 compound treatment 0.353 0.00668 0.55 0.344 -0.00307 -0.27 0.1998 0.3236 1741759 CBMicro_026766 COc1ccc(cc1)C(=O)Nc2ccc(cc2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K09 compound treatment 0.346 -3.23E-4 -0.03 0.343 -0.00407 -0.36 -0.2738 -0.7576 1481039 CBMicro_026767 NC(=O)c1cc(NC(=O)c2cccs2)c(Cl)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K10 compound treatment 0.36 0.0137 1.14 0.355 0.00793 0.7 1.3001 0.9734 1938961 CBMicro_026768 Oc1c2CCCc2nn1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K11 compound treatment 0.376 0.0297 2.46 0.366 0.0189 1.68 2.9286 0.9825 1938962 CBMicro_026769 CC1=NN(C(=O)C1C(c2c(C)nn(c2O)c3ccc(C)cc3)c4ccccc4O)c5ccc(C)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K12 compound treatment 0.351 0.00468 0.39 0.355 0.00793 0.7 0.7717 0.9608 1199850 CBMicro_026770 Clc1ccc(OCC(=O)Nc2nnc(s2)c3ccco3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K13 compound treatment 0.347 6.77E-4 0.06 0.349 0.00193 0.17 0.1609 0.8924 1938963 CBMicro_026771 COc1ccc(Cl)cc1/N=C/c2ccc(OC3CSC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K14 compound treatment 0.356 0.00968 0.8 0.36 0.0129 1.15 1.3786 0.9849 1473766 CBMicro_026772 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(Cl)cc4)C(=O)Cc5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K15 compound treatment 0.358 0.0117 0.97 0.351 0.00393 0.35 0.932 0.9047 1938964 CBMicro_026773 CC/1=NN(C(=O)\C1=C/NNC(=O)c2ccccc2[N+](=O)[O-])c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K16 compound treatment 0.376 0.0297 2.46 0.381 0.0339 3.01 3.8686 0.9951 1938965 CBMicro_026774 CCOc1ccc(NC(=O)C2C(c3ccccc3)C2(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K17 compound treatment 0.381 0.0347 2.88 0.365 0.0179 1.59 3.1595 0.9608 1938966 CBMicro_026775 Fc1ccc(NC=C2C(=O)NC(=O)NC2=O)cc1F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K18 compound treatment 0.365 0.0187 1.55 0.36 0.0129 1.15 1.9069 0.9889 1123324 CBMicro_026776 O=C(N1CCCc2ccccc12)c3ccccc3CCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K19 compound treatment 0.336 -0.0103 -0.86 0.325 -0.0221 -1.96 -1.9888 -0.9315 1672264 CBMicro_026777 CCCC(=O)Nc1nnc(COc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K20 compound treatment 0.362 0.0157 1.3 0.356 0.00893 0.79 1.4801 0.9716 1938967 CBMicro_026778 Fc1ccccc1NC(=O)c2ccc(CSc3ccc(Cl)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K21 compound treatment 0.355 0.00868 0.72 0.348 9.33E-4 0.08 0.5679 0.7832 1938968 CBMicro_026779 Cc1ccc(/C=N/NC(=O)CSc2ncccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K22 compound treatment 0.351 0.00468 0.39 0.35 0.00293 0.26 0.4584 0.981 1938969 CBMicro_026780 Clc1ccc(C(=O)NN2C(=O)C3C4C=CC(C3C2=O)C54CC5)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K23 positive control 0.087 -0.259 -21.53 0.088 -0.259 -22.96 -31.4575 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 K24 positive control 0.09 -0.256 -21.28 0.097 -0.25 -22.16 -30.7174 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L01 mock treatment 0.344 -0.00232 -0.19 0.35 0.00293 0.26 0.0475 0.1467 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L02 mock treatment 0.348 0.00168 0.14 0.349 0.00193 0.17 0.2196 0.9947 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L03 compound treatment 0.353 0.00668 0.55 0.348 9.33E-4 0.08 0.4505 0.8037 1938970 CBMicro_026781 Cc1ccccc1N2C(=O)/C(=C\c3cccs3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L04 compound treatment 0.357 0.0107 0.89 0.357 0.00993 0.88 1.2493 1.0 1938971 CBMicro_026782 Clc1ccc(OCCSc2ncnc3[nH]cnc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L05 compound treatment 0.347 6.77E-4 0.06 0.353 0.00593 0.53 0.4116 0.7783 1938972 CBMicro_026783 Cc1cc(NC(=O)CCN2C(=O)/C(=C/c3ccccc3)/SC2=S)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L06 compound treatment 0.349 0.00268 0.22 0.354 0.00693 0.61 0.5917 0.9055 1938973 CBMicro_026784 COc1ccc(C/N=C/c2ccc(OC3CSC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L07 compound treatment 0.359 0.0127 1.05 0.353 0.00593 0.53 1.116 0.9486 1735579 CBMicro_026785 CC(C)c1ccc(NC(=O)c2ccccc2CCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L08 compound treatment 0.349 0.00268 0.22 0.355 0.00793 0.7 0.6543 0.8874 1938974 CBMicro_026786 COc1ccc(cc1)N(C(C)C(=O)N/N=C/c2ccc(N(C)C)c(Br)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L09 compound treatment 0.369 0.0227 1.88 0.365 0.0179 1.59 2.455 0.9964 1938975 CBMicro_026787 CC1(C)C(C(=O)Nc2ccc(Br)cc2)C1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L10 compound treatment 0.35 0.00368 0.31 0.347 -6.67E-5 -0.01 0.2117 0.6933 1509605 CBMicro_026788 CN(C)c1ccc(NC(=O)COc2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L11 compound treatment 0.413 0.0667 5.54 0.41 0.0629 5.58 7.8579 1.0 1461529 CBMicro_026789 Cn1c(=O)c(N)c2-c3ccccc3C(=O)c4c(Br)ccc1c42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L12 compound treatment 0.355 0.00868 0.72 0.357 0.00993 0.88 1.1319 0.995 1938976 CBMicro_026790 CCOc1ccc(/C=C(/NC(=O)c2ccc(C)cc2)\C(=O)NCCO)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L13 compound treatment 0.357 0.0107 0.89 0.351 0.00393 0.35 0.8733 0.9168 1938977 CBMicro_026791 Cc1cccc(/N=C/c2ccc(OC3CSC3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L14 compound treatment 0.352 0.00568 0.47 0.343 -0.00407 -0.36 0.0784 0.1322 1938978 CBMicro_026792 C/C(=N\NC(=O)c1ccc(O)cc1O)/c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L15 compound treatment 0.357 0.0107 0.89 0.349 0.00193 0.17 0.748 0.8284 1938979 CBMicro_026793 COC(=O)CN(c1ccc(Cl)c(Cl)c1)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L16 compound treatment 0.349 0.00268 0.22 0.347 -6.67E-5 -0.01 0.153 0.6881 1938980 CBMicro_026794 CC(C)c1nccn1S(=O)(=O)c2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L17 compound treatment 0.13 -0.216 -17.96 0.136 -0.211 -18.71 -25.9254 -0.9998 1938981 CBMicro_026795 OC(=O)COc1ccc(cc1)N2C(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L18 compound treatment 0.427 0.0807 6.7 0.442 0.0949 8.41 10.685 0.9936 1938982 CBMicro_026796 Oc1ccc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L19 compound treatment 0.347 6.77E-4 0.06 0.346 -0.00107 -0.09 -0.0271 -0.2462 1938983 CBMicro_026797 COc1cc(/C=N/Nc2nonc2N)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L20 compound treatment 0.348 0.00168 0.14 0.355 0.00793 0.7 0.5956 0.831 1938984 CBMicro_026798 COc1ccc(cc1F)C2=CSC3=NCCN23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L21 compound treatment 0.355 0.00868 0.72 0.348 9.33E-4 0.08 0.5679 0.7832 1938985 CBMicro_026799 COC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L22 compound treatment 0.348 0.00168 0.14 0.352 0.00493 0.44 0.4076 0.8884 1371773 CBMicro_026800 COc1ccc(cc1OC)C(=O)NC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L23 positive control 0.087 -0.259 -21.53 0.087 -0.26 -23.05 -31.5202 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 L24 positive control 0.09 -0.256 -21.28 0.093 -0.254 -22.52 -30.9681 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M01 mock treatment 0.343 -0.00332 -0.28 0.35 0.00293 0.26 -0.0112 -0.0296 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M02 mock treatment 0.343 -0.00332 -0.28 0.347 -6.67E-5 -0.01 -0.1992 -0.7221 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M03 compound treatment 0.349 0.00268 0.22 0.343 -0.00407 -0.36 -0.0977 -0.2307 1938986 CBMicro_026801 O=C1CCCc2nn(nc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M04 compound treatment 0.356 0.00968 0.8 0.355 0.00793 0.7 1.0652 0.9978 1938987 CBMicro_026802 COC(=O)c1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M05 compound treatment 0.447 0.101 8.36 0.454 0.107 9.48 12.6111 0.998 1938988 CBMicro_026803 Cc1nn(c(O)c1/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M06 compound treatment 0.359 0.0127 1.05 0.359 0.0119 1.06 1.492 1.0 1064616 CBMicro_026804 OCCNc1ccc(NCCO)c2C(=O)c3ccccc3C(=O)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M07 compound treatment 0.354 0.00768 0.64 0.347 -6.67E-5 -0.01 0.4465 0.7005 1938989 CBMicro_026805 CCSc1nnc(NC(=O)COC(=O)C(CCSC)NC(=O)C)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M08 compound treatment 0.348 0.00168 0.14 0.348 9.33E-4 0.08 0.157 0.9691 1197179 CBMicro_026806 CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3cc(C)cc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M09 compound treatment 0.354 0.00768 0.64 0.353 0.00593 0.53 0.8225 0.9954 1938990 CBMicro_026807 COc1ccccc1/C=N/NC(=O)CSc2nc(C)cc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M10 compound treatment 0.344 -0.00232 -0.19 0.341 -0.00607 -0.54 -0.5165 -0.9043 1938991 CBMicro_026808 O=C(CN1CCOCC1)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M11 compound treatment 0.35 0.00368 0.31 0.351 0.00393 0.35 0.4624 0.9978 1938992 CBMicro_026809 C/C(=N\NC(=O)c1ccc(C)cc1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M12 compound treatment 0.354 0.00768 0.64 0.351 0.00393 0.35 0.6972 0.9597 1281556 CBMicro_026810 NC(=O)c1cc(NC(=O)c2cccs2)cc(c1)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M13 compound treatment 0.345 -0.00132 -0.11 0.348 9.33E-4 0.08 -0.0192 -0.1393 1397912 CBMicro_026811 Cc1cc(C)cc(c1)N(CC(=O)O)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M14 compound treatment 0.356 0.00968 0.8 0.352 0.00493 0.44 0.8772 0.9591 1245781 CBMicro_026812 COc1ccc(cc1)c2nnc(NC(=O)c3cccs3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M15 compound treatment 0.356 0.00968 0.8 0.359 0.0119 1.06 1.3159 0.9908 1727084 CBMicro_026813 Cc1ccc(NC2CS(=O)(=O)C=C2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M16 compound treatment 0.344 -0.00232 -0.19 0.351 0.00393 0.35 0.1101 0.2765 1340674 CBMicro_026814 CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M17 compound treatment 0.394 0.0477 3.96 0.393 0.0459 4.07 5.6772 0.9999 1132373 CBMicro_026815 Cc1ccccc1C(=O)Nc2nnc(s2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M18 compound treatment 0.358 0.0117 0.97 0.353 0.00593 0.53 1.0573 0.9587 1938993 CBMicro_026816 COc1ccc(CCNC=C2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M19 compound treatment 0.353 0.00668 0.55 0.351 0.00393 0.35 0.6385 0.975 1938994 CBMicro_026817 COc1ccc(Br)cc1/C=N/NC(=O)C(C)Sc2nc(C)cc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M20 compound treatment 0.391 0.0447 3.71 0.395 0.0479 4.25 5.6265 0.9977 1938995 CBMicro_026818 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M21 compound treatment 0.349 0.00268 0.22 0.347 -6.67E-5 -0.01 0.153 0.6881 1938996 CBMicro_026819 C/C(=N\NC(=O)c1cccc(Cl)c1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M22 compound treatment 0.351 0.00468 0.39 0.35 0.00293 0.26 0.4584 0.981 1938997 CBMicro_026820 [O-][N+](=O)c1ccccc1/C=N/NC(=O)CSc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M23 positive control 0.087 -0.259 -21.53 0.088 -0.259 -22.96 -31.4575 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 M24 positive control 0.092 -0.254 -21.11 0.093 -0.254 -22.52 -30.8507 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N01 mock treatment 0.352 0.00568 0.47 0.349 0.00193 0.17 0.4544 0.9061 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N02 mock treatment 0.35 0.00368 0.31 0.355 0.00793 0.7 0.713 0.9302 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N03 compound treatment 0.35 0.00368 0.31 0.351 0.00393 0.35 0.4624 0.9978 1231887 CBMicro_026821 COc1ccc(cc1OC)c2nnc(NC(=O)c3ccc(Cl)cc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N04 compound treatment 0.356 0.00968 0.8 0.351 0.00393 0.35 0.8146 0.9301 1731002 CBMicro_026822 Cc1ccc(cc1)c2nnc(NC(=O)c3cccs3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N05 compound treatment 0.351 0.00468 0.39 0.354 0.00693 0.61 0.7091 0.9755 1938998 CBMicro_026823 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N06 compound treatment 0.357 0.0107 0.89 0.354 0.00693 0.61 1.0613 0.984 1938999 CBMicro_026824 CC(=O)c1ccc(NC(=O)COc2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N07 compound treatment 0.358 0.0117 0.97 0.35 0.00293 0.26 0.8693 0.8661 1607232 CBMicro_026825 CC(Oc1ccccc1)C(=O)Nc2ccc(Cl)c(c2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N08 compound treatment 0.207 -0.139 -11.57 0.209 -0.138 -12.24 -16.8307 -0.9996 1939000 CBMicro_026826 OC(=O)c1cc(ccc1Cl)N2C(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N09 compound treatment 0.364 0.0177 1.47 0.354 0.00693 0.61 1.4722 0.9253 1939001 CBMicro_026827 CN(C)c1ccc(/C=N/n2cnc3sc4CCCCc4c3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N10 compound treatment 0.358 0.0117 0.97 0.35 0.00293 0.26 0.8693 0.8661 1428035 CBMicro_026828 Cc1onc(c1C(=O)Nc2cc(cc(c2)C(=O)N)C(=O)N)c3c(Cl)cccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N11 compound treatment 0.406 0.0597 4.95 0.4 0.0529 4.69 6.8203 0.9996 1939002 CBMicro_026829 CC(C)c1ccc(/C=C/C(=O)Nc2ccc(cc2)C(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N12 compound treatment 0.355 0.00868 0.72 0.364 0.0169 1.5 1.5705 0.9435 1638564 CBMicro_026830 CCOc1ccccc1NC(=O)c2ccc(cc2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N13 compound treatment 0.357 0.0107 0.89 0.356 0.00893 0.79 1.1866 0.9984 1939003 CBMicro_026831 CCOC(=O)C1=NNC2C1C(=O)N(Cc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N14 compound treatment 0.372 0.0257 2.13 0.362 0.0149 1.32 2.4431 0.9737 1246044 CBMicro_026832 CCOC(=O)c1cnc2c(c(C)nn2c1C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N15 compound treatment 0.355 0.00868 0.72 0.346 -0.00107 -0.09 0.4425 0.6091 1527821 CBMicro_026833 CC(Oc1ccccc1)C(=O)Nc2cc(C(=O)N)c(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N16 compound treatment 0.217 -0.129 -10.74 0.214 -0.133 -11.79 -15.9303 -0.9989 1939004 CBMicro_026834 Oc1ccc(/C=N/NC(=O)c2ccc(Cl)cc2Cl)c(O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N17 compound treatment 0.359 0.0127 1.05 0.36 0.0129 1.15 1.5547 0.9991 1779200 CBMicro_026835 Cc1cccc(C)c1OC(=O)c2ccc(cc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N18 compound treatment 0.355 0.00868 0.72 0.361 0.0139 1.23 1.3825 0.9671 1781077 CBMicro_026836 COc1ccc(cc1OC)C(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N19 compound treatment 0.375 0.0287 2.38 0.37 0.0229 2.03 3.1206 0.9969 1149301 CBMicro_026837 COC(=O)c1ccc(CN(c2ccccc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N20 compound treatment 0.56 0.214 17.74 0.552 0.205 18.16 25.3857 0.9999 1939005 CBMicro_026838 COc1cc(/C=C(\C#N)/c2nc3ccccc3[nH]2)c(Br)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N21 compound treatment 0.361 0.0147 1.22 0.363 0.0159 1.41 1.8601 0.9973 1939006 CBMicro_026839 CC(Sc1nc(C)cc(C)n1)C(=O)N/N=C/c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N22 compound treatment 0.36 0.0137 1.14 0.356 0.00893 0.79 1.3627 0.9845 1939007 CBMicro_026840 CC(C)(C)NC(=O)C(=O)N/N=C/c1c(Cl)cccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N23 positive control 0.087 -0.259 -21.53 0.088 -0.259 -22.96 -31.4575 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 N24 positive control 0.091 -0.255 -21.2 0.096 -0.251 -22.25 -30.7214 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O01 mock treatment 0.348 0.00168 0.14 0.35 0.00293 0.26 0.2823 0.9572 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O02 mock treatment 0.35 0.00368 0.31 0.352 0.00493 0.44 0.525 0.9846 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O03 compound treatment 0.353 0.00668 0.55 0.351 0.00393 0.35 0.6385 0.975 1739146 CBMicro_026841 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccccc5Cl)C(=O)CC(C)(C)C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O04 compound treatment 0.352 0.00568 0.47 0.35 0.00293 0.26 0.5171 0.9607 1939008 CBMicro_026842 S=c1[nH]cnc2sc3CCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O05 compound treatment 0.534 0.188 15.58 0.515 0.168 14.88 21.5408 0.9997 1939009 CBMicro_026843 OC1=c2ccccc2=C(O)C31Nn4c(S)nnc4N=N3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O06 compound treatment 0.352 0.00568 0.47 0.356 0.00893 0.79 0.8931 0.9693 1939010 CBMicro_026844 O=C(N/N=C/1\C(=O)N(Cc2ccccc2)c3ccccc13)c4ccc5ccccc5n4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O07 compound treatment 0.363 0.0167 1.38 0.355 0.00793 0.7 1.4762 0.9506 1939011 CBMicro_026845 C=CCN1C(=O)/C(=C\c2cccs2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O08 compound treatment 0.351 0.00468 0.39 0.358 0.0109 0.97 0.9597 0.9194 1545243 CBMicro_026846 COc1ccc(cc1)C(=O)Nc2nnc(s2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O09 compound treatment 0.361 0.0147 1.22 0.352 0.00493 0.44 1.1708 0.9044 1939012 CBMicro_026847 CC(Oc1ccccc1)C(=O)Nc2ccc(cc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O10 compound treatment 0.352 0.00568 0.47 0.352 0.00493 0.44 0.6424 0.9993 1939013 CBMicro_026848 CC(Sc1nc(C)cc(C)n1)C(=O)N/N=C(\C)/c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O11 compound treatment 0.355 0.00868 0.72 0.353 0.00593 0.53 0.8812 0.988 1939014 CBMicro_026849 CCOC(=O)C(C)N(c1ccc(OC)cc1)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O12 compound treatment 0.36 0.0137 1.14 0.352 0.00493 0.44 1.1121 0.914 1194268 CBMicro_026850 CC1=CC(C)(C)N(C(=O)CN2C(=O)c3ccccc3C2=O)c4cc(C)ccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O13 compound treatment 0.353 0.00668 0.55 0.347 -6.67E-5 -0.01 0.3878 0.6995 1939015 CBMicro_026851 Fc1cccc(/C=N/NC(=O)Cc2c[nH]c3ccccc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O14 compound treatment 0.356 0.00968 0.8 0.354 0.00693 0.61 1.0026 0.9912 1939016 CBMicro_026852 Fc1ccc(/C=N/NC(=O)CSc2ncccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O15 compound treatment 0.359 0.0127 1.05 0.362 0.0149 1.32 1.68 0.9936 1939017 CBMicro_026853 Nc1nc(/N=C/c2ccc(F)cc2)n[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O16 compound treatment 0.355 0.00868 0.72 0.352 0.00493 0.44 0.8185 0.9714 1939018 CBMicro_026854 COc1ccc(/C=C/C(=O)Nc2ccc3c(c2)oc4ccccc43)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O17 compound treatment 0.391 0.0447 3.71 0.379 0.0319 2.83 4.6238 0.9911 1360642 CBMicro_026855 COc1ccc(Cl)cc1NC(=O)c2ccccc2N(Cc3ccccc3)S(=O)(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O18 compound treatment 0.349 0.00268 0.22 0.353 0.00593 0.53 0.529 0.9266 1939019 CBMicro_026856 COC(=O)CN(c1ccc(C)cc1)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O19 compound treatment 0.36 0.0137 1.14 0.352 0.00493 0.44 1.1121 0.914 1939020 CBMicro_026857 CCOc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O20 compound treatment 0.364 0.0177 1.47 0.37 0.0229 2.03 2.4748 0.9872 1939021 CBMicro_026858 O=C/1Nc2ccccc2\C1=C/3\S/C(=N\Nc4ccccc4)/N(C3=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O21 compound treatment 0.352 0.00568 0.47 0.358 0.0109 0.97 1.0184 0.9452 1711876 CBMicro_026859 COC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O22 compound treatment 0.356 0.00968 0.8 0.354 0.00693 0.61 1.0026 0.9912 1939022 CBMicro_026860 CC(=O)NNc1nc2ccccc2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O23 positive control 0.086 -0.26 -21.61 0.086 -0.261 -23.14 -31.6416 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 O24 positive control 0.092 -0.254 -21.11 0.094 -0.253 -22.43 -30.788 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P01 mock treatment 0.348 0.00168 0.14 0.344 -0.00307 -0.27 -0.0937 -0.3068 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P02 mock treatment 0.352 0.00568 0.47 0.351 0.00393 0.35 0.5798 0.989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P03 compound treatment 0.369 0.0227 1.88 0.357 0.00993 0.88 1.9537 0.9401 1939023 CBMicro_026861 COc1ccc2oc(=O)c(cc2c1)c3csc(/N=C/c4ccccc4O)n3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P04 compound treatment 0.38 0.0337 2.8 0.384 0.0369 3.27 4.2914 0.9969 1939024 CBMicro_026862 CC(C)c1ccc2[nH]c3/C(=N/NC(=O)c4ccncc4)/CCCc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P05 compound treatment 0.337 -0.00932 -0.77 0.361 0.0139 1.23 0.3259 0.2236 1939025 CBMicro_026863 Clc1ccccc1/C=N/NC(=O)CSc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P06 compound treatment 0.361 0.0147 1.22 0.364 0.0169 1.5 1.9227 0.9947 1463463 CBMicro_026864 Cc1ccc2-c3c(sn(c4ccc(Cl)c(F)c4)c3=S)C(C)(C)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P07 compound treatment 0.357 0.0107 0.89 0.354 0.00693 0.61 1.0613 0.984 1662866 CBMicro_026865 Cc1ccc(cc1)c2nnc(NC(=O)c3ccccc3C)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P08 compound treatment 0.356 0.00968 0.8 0.356 0.00893 0.79 1.1279 1.0 1939026 CBMicro_026866 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)cc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P09 compound treatment 0.352 0.00568 0.47 0.354 0.00693 0.61 0.7678 0.9914 1577310 CBMicro_026867 Cc1ccnc(c1)N2C(=O)c3ccc(cc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P10 compound treatment 0.346 -3.23E-4 -0.03 0.354 0.00693 0.61 0.4155 0.6756 1939027 CBMicro_026868 CC(=O)c1ccc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P11 compound treatment 0.344 -0.00232 -0.19 0.351 0.00393 0.35 0.1101 0.2765 1647138 CBMicro_026869 COc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P12 compound treatment 0.344 -0.00232 -0.19 0.353 0.00593 0.53 0.2355 0.4204 1138545 CBMicro_026870 C(N1CCOCC1)C2(CC3CC4C2)CC(C3)CC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P13 compound treatment 0.371 0.0247 2.05 0.366 0.0189 1.68 2.6351 0.9951 1612162 CBMicro_026871 Clc1ccc(c2nnc(NC(=O)Nc3ccccc3)s2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P14 compound treatment 0.36 0.0137 1.14 0.362 0.0149 1.32 1.7387 0.9971 1235996 CBMicro_026872 COc1cc2c(cc1NC(=O)c3c(C)onc3c4ccccc4Cl)oc5ccccc52 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P15 compound treatment 0.376 0.0297 2.46 0.386 0.0389 3.45 4.1819 0.9864 1368071 CBMicro_026873 Cc1cccc(N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P16 compound treatment 0.347 6.77E-4 0.06 0.359 0.0119 1.06 0.7876 0.7437 1670415 CBMicro_026874 CC1=NN(C(C1)c2ccc(O)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P17 compound treatment 0.35 0.00368 0.31 0.359 0.0119 1.06 0.9637 0.8755 1939028 CBMicro_026875 C/C(=N\NC(=O)COc1ccc(Cl)cc1Cl)/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P18 compound treatment 0.357 0.0107 0.89 0.352 0.00493 0.44 0.9359 0.9469 1122276 CBMicro_026876 COc1ccc2oc(=O)c(cc2c1)C(=O)N3CCN(C)CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P19 compound treatment 0.362 0.0157 1.3 0.356 0.00893 0.79 1.4801 0.9716 1317046 CBMicro_026877 COc1ccc(cc1OC)c2nnc(NC(=O)c3ccc(C)cc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P20 compound treatment 0.374 0.0277 2.3 0.369 0.0219 1.94 2.9992 0.9965 1939029 CBMicro_026878 Brc1ccc(cc1)C2SCCN2S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P21 compound treatment 0.352 0.00568 0.47 0.355 0.00793 0.7 0.8304 0.9811 1939030 CBMicro_026879 Fc1ccc(/C=C/C(=O)Nc2ccc(cc2)N3CCOCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P22 compound treatment 0.357 0.0107 0.89 0.344 -0.00307 -0.27 0.4346 0.4688 1939031 CBMicro_026880 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C\c3ccccc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P23 positive control 0.088 -0.258 -21.45 0.089 -0.258 -22.87 -31.3362 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.769 P24 positive control 0.093 -0.253 -21.03 0.094 -0.253 -22.43 -30.7293 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A01 mock treatment 0.325 -0.0183 -1.52 0.326 -0.0145 -1.29 -1.9843 -0.9966 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A02 mock treatment 0.33 -0.0133 -1.1 0.335 -0.00553 -0.49 -1.1268 -0.9333 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A03 compound treatment 0.33 -0.0133 -1.1 0.336 -0.00453 -0.4 -1.0641 -0.9063 1939032 CBMicro_026881 COc1ccccc1OCCSc2nc3ccccc3n2CCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A04 compound treatment 0.334 -0.00929 -0.77 0.334 -0.00653 -0.58 -0.9547 -0.99 1939033 CBMicro_026882 CN(C)c1ccc(cc1)n2c(C)c(C(=O)C)c3cc(O)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A05 compound treatment 0.333 -0.0103 -0.85 0.334 -0.00653 -0.58 -1.0134 -0.982 1155149 CBMicro_026883 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCc2ccc(Cl)cc2)c3cc(C)cc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A06 compound treatment 0.329 -0.0143 -1.19 0.333 -0.00753 -0.67 -1.3108 -0.963 1255971 CBMicro_026884 Cc1oc(cc1COc2ccc(cc2)C(=O)N)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A07 compound treatment 0.328 -0.0153 -1.27 0.337 -0.00353 -0.31 -1.1189 -0.8558 1939034 CBMicro_026885 C/C(=N\NC(=O)C(O)(c1ccccc1)c2ccccc2)/c3ccc(Cl)s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A08 compound treatment 0.328 -0.0153 -1.27 0.334 -0.00653 -0.58 -1.3069 -0.9367 1939035 CBMicro_026886 CCN(CC)c1ccc(/C=C/2\SC(=S)NC2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A09 compound treatment 0.329 -0.0143 -1.19 0.327 -0.0135 -1.2 -1.6868 -1.0 1939036 CBMicro_026887 OCCCCCCOC(=O)/C=C/C(=O)OCCCCCCOC(=O)\C=C\C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A10 compound treatment 0.336 -0.00729 -0.61 0.31 -0.0305 -2.71 -2.3412 -0.8444 1939037 CBMicro_026888 Fc1ccc(cc1)c2ccc(/C=C\3/SC(=S)NC3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A11 compound treatment 0.338 -0.00529 -0.44 0.353 0.0125 1.11 0.4708 0.3959 1939038 CBMicro_026889 CN(C)c1ccc(NC(=O)/C=C/c2ccccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A12 compound treatment 0.335 -0.00829 -0.69 0.338 -0.00253 -0.22 -0.6453 -0.8914 1939039 CBMicro_026890 COc1ccc2n(C)c(SCc3ccccc3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A13 compound treatment 0.334 -0.00929 -0.77 0.332 -0.00853 -0.76 -1.08 -1.0 1283938 CBMicro_026891 COc1ccc(cc1OC)c2nnc(NC(=O)c3ccccc3C)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A14 compound treatment 0.336 -0.00729 -0.61 0.331 -0.00953 -0.84 -1.0252 -0.9866 1564216 CBMicro_026892 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4ccc(cc4)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A15 compound treatment 0.333 -0.0103 -0.85 0.334 -0.00653 -0.58 -1.0134 -0.982 1872897 CBMicro_026893 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A16 compound treatment 0.33 -0.0133 -1.1 0.333 -0.00753 -0.67 -1.2521 -0.971 1662960 CBMicro_026894 COc1ccc(OC)c(c1)S(=O)(=O)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A17 compound treatment 0.335 -0.00829 -0.69 0.331 -0.00953 -0.84 -1.0839 -0.9948 1700587 CBMicro_026895 Brc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A18 compound treatment 0.331 -0.0123 -1.02 0.333 -0.00753 -0.67 -1.1934 -0.9788 1939040 CBMicro_026896 c1ccc(cc1)C(c2nnc(o2)C(c3ccccc3)c4ccccc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A19 compound treatment 0.33 -0.0133 -1.1 0.332 -0.00853 -0.76 -1.3148 -0.983 1939041 CBMicro_026897 CC(=O)Nc1nnc(Cc2ccc(Cl)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A20 compound treatment 0.329 -0.0143 -1.19 0.33 -0.0105 -0.93 -1.4988 -0.9929 1939042 CBMicro_026898 [O-][N+](=O)c1ccc2NC(=O)/C(=C/3\S/C(=N\c4ccccc4)/N(C3=O)c5ccccc5)/c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A21 compound treatment 0.326 -0.0173 -1.44 0.326 -0.0145 -1.29 -1.9256 -0.9985 1939043 CBMicro_026899 COc1ccc(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A22 compound treatment 0.332 -0.0113 -0.94 0.324 -0.0165 -1.47 -1.6987 -0.9767 1633386 CBMicro_026900 CCOC(=O)COc1ccc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A23 positive control 0.093 -0.25 -20.78 0.095 -0.246 -21.76 -30.0791 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 A24 positive control 0.084 -0.259 -21.53 0.087 -0.254 -22.47 -31.1088 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B01 mock treatment 0.323 -0.0203 -1.68 0.333 -0.00753 -0.67 -1.6631 -0.9179 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B02 mock treatment 0.353 0.00971 0.81 0.343 0.00247 0.22 0.7247 0.8676 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B03 compound treatment 0.345 0.00171 0.14 0.343 0.00247 0.22 0.2551 0.9781 1939044 CBMicro_026901 [O-][N+](=O)c1ccc(cc1)c2ccc(N/C=C\3/N=C(OC3=O)c4ccccc4)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B04 compound treatment 0.352 0.00871 0.72 0.346 0.00547 0.48 0.854 0.9811 1939045 CBMicro_026902 CCCCCCOc1ccc(cc1)N2C(=O)CC(NCCc3ccc(OC)c(OC)c3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B05 compound treatment 0.341 -0.00229 -0.19 0.347 0.00647 0.57 0.2709 0.4485 1939046 CBMicro_026903 Fc1cccc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B06 compound treatment 0.342 -0.00129 -0.11 0.34 -5.31E-4 -0.05 -0.109 -0.9319 1939047 CBMicro_026904 COc1ccc(Br)cc1c2nc3nnc(C)n3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B07 compound treatment 0.354 0.0107 0.89 0.338 -0.00253 -0.22 0.4701 0.5126 1652946 CBMicro_026905 COc1ccccc1C2SCCN2S(=O)(=O)c3ccc4ccccc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B08 compound treatment 0.347 0.00371 0.31 0.341 4.69E-4 0.04 0.2471 0.7953 1229637 CBMicro_026906 CC(=O)Nc1nc2ccccc2n1Cc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B09 compound treatment 0.368 0.0247 2.05 0.356 0.0155 1.37 2.4199 0.9808 1939048 CBMicro_026907 Cc1ccc2[nH]c(nc2c1)/C(=C/c3cc(Br)ccc3OCc4ccccc4)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B10 compound treatment 0.344 7.1E-4 0.06 0.34 -5.31E-4 -0.05 0.0084 0.111 1575527 CBMicro_026908 Cc1nc2c(=O)[nH]c3ccccc3c2o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B11 compound treatment 0.359 0.0157 1.3 0.34 -5.31E-4 -0.05 0.8889 0.6811 1939049 CBMicro_026909 Cc1ccc(cc1)c2noc(n2)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B12 compound treatment 0.358 0.0147 1.22 0.351 0.0105 0.93 1.5195 0.9908 1939050 CBMicro_026910 Ic1ccc2NC(=O)/C(=C/3\NC(=S)NC3=O)/c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B13 compound treatment 0.35 0.00671 0.56 0.348 0.00747 0.66 0.8619 0.9963 1939051 CBMicro_026911 CCCCCCCc1ccc(cc1)C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B14 compound treatment 0.518 0.175 14.5 0.523 0.182 16.17 21.6905 0.9985 1939052 CBMicro_026912 Cc1c(cc2nc(O)c(O)nc2c1[N+](=O)[O-])[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B15 compound treatment 0.351 0.00771 0.64 0.343 0.00247 0.22 0.6073 0.8978 1703779 CBMicro_026913 Clc1cccc(c1)N2CCN(CC2)C(=O)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B16 compound treatment 0.681 0.338 28.04 0.681 0.34 30.17 41.1602 0.9993 1939053 CBMicro_026914 OCC1(CO)COC(=O)/C(=N/Nc2ccc(cc2)[N+](=O)[O-])/N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B17 compound treatment 0.341 -0.00229 -0.19 0.344 0.00347 0.31 0.0829 0.2294 1939054 CBMicro_026915 OC(=O)CCCNS(=O)(=O)c1ccc(Br)c(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B18 compound treatment 0.35 0.00671 0.56 0.343 0.00247 0.22 0.5486 0.9167 1491540 CBMicro_026916 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5nnn[nH]5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B19 compound treatment 0.341 -0.00229 -0.19 0.34 -5.31E-4 -0.05 -0.1677 -0.8563 1175042 CBMicro_026917 COc1ccc(cc1)C(=O)Nc2nc(c(C)s2)C3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B20 compound treatment 0.346 0.00271 0.22 0.343 0.00247 0.22 0.3138 0.9999 1939055 CBMicro_026918 CC(=C)C1CC=C(C)C(=NNC(=O)c2cccc(c2)[N+](=O)[O-])C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B21 compound treatment 0.398 0.0547 4.54 0.358 0.0175 1.55 4.3063 0.8974 1939056 CBMicro_026919 COc1cc(/C=C/2\SC(=S)NC2=O)ccc1OCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B22 compound treatment 0.338 -0.00529 -0.44 0.337 -0.00353 -0.31 -0.5318 -0.9862 1864103 CBMicro_026920 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B23 positive control 0.081 -0.262 -21.78 0.085 -0.256 -22.65 -31.4102 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 B24 positive control 0.091 -0.252 -20.94 0.094 -0.247 -21.85 -30.2592 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C01 mock treatment 0.349 0.00571 0.47 0.341 4.69E-4 0.04 0.3646 0.7661 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C02 mock treatment 0.356 0.0127 1.06 0.346 0.00547 0.48 1.0888 0.9377 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C03 compound treatment 0.373 0.0297 2.47 0.372 0.0315 2.79 3.716 0.9981 1939057 CBMicro_026921 Cc1cc(C)nc(SCC(=O)N/N=C/c2cc(ccc2O)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C04 compound treatment 0.349 0.00571 0.47 0.353 0.0125 1.11 1.1165 0.9286 1407408 CBMicro_026922 Brc1cccc(NC(=O)c2ccc(cc2)N3C(=O)c4cccnc4C3=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C05 compound treatment 0.348 0.00471 0.39 0.339 -0.00153 -0.14 0.1805 0.4362 1939058 CBMicro_026923 COC(=O)COc1ccc(/C=N/NC(=O)CSc2nc(C)cc(C)n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C06 compound treatment 0.348 0.00471 0.39 0.343 0.00247 0.22 0.4312 0.9624 1939059 CBMicro_026924 O=S(=O)(N1CCCCC1)c2ccc(cc2)C3=CSC4=NCCN34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C07 compound treatment 0.354 0.0107 0.89 0.356 0.0155 1.37 1.598 0.978 1939060 CBMicro_026925 CC(Sc1nc(C)cc(C)n1)C(=O)N/N=C(\C)/c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C08 compound treatment 0.373 0.0297 2.47 0.373 0.0325 2.88 3.7787 0.9971 1315483 CBMicro_026926 COc1ccc(OC)c(NCC(O)Cn2c3ccccc3c4ccccc24)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C09 compound treatment 0.361 0.0177 1.47 0.354 0.0135 1.19 1.8836 0.9947 1939061 CBMicro_026927 Cc1cc(C)cc(OCC(=O)NNC(=O)CN2C(=O)c3ccccc3C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C10 compound treatment 0.358 0.0147 1.22 0.351 0.0105 0.93 1.5195 0.9908 1939062 CBMicro_026928 COc1ccc(/C=N\NC(=O)c2ccc(cc2)S(=O)(=O)c3ccc(cc3)C(=O)N/N=C\c4ccc(OC)cc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C11 compound treatment 0.378 0.0347 2.88 0.349 0.00847 0.75 2.5683 0.8625 1939063 CBMicro_026929 CCOC(=O)C1=C(C)NC(=S)NC1c2cn(nc2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C12 compound treatment 0.349 0.00571 0.47 0.349 0.00847 0.75 0.8659 0.9754 1939064 CBMicro_026930 CCCOc1ccc(cc1)N2C(=O)CC(N3CCN(CC3)C(=O)OCC)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C13 compound treatment 0.394 0.0507 4.21 0.379 0.0385 3.41 5.3875 0.9945 1501283 CBMicro_026931 COc1ccc2c(C)cc(=S)[nH]c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C14 compound treatment 0.35 0.00671 0.56 0.342 0.00147 0.13 0.4859 0.8495 1738533 CBMicro_026932 O=C(CNC(=O)c1ccccc1)N2CC(=O)NC(=O)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C15 compound treatment 0.348 0.00471 0.39 0.343 0.00247 0.22 0.4312 0.9624 1692978 CBMicro_026933 CS(=O)(=O)N(CC(=O)NCc1cccnc1)c2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C16 compound treatment 0.392 0.0487 4.04 0.388 0.0475 4.21 5.8341 0.9998 1939065 CBMicro_026934 CC(=O)c1cccc(N/C=C/2\N=C(OC2=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C17 compound treatment 0.35 0.00671 0.56 0.35 0.00947 0.84 0.9872 0.9802 1939066 CBMicro_026935 O=C(NCCN1CCNCC1)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C18 compound treatment 0.35 0.00671 0.56 0.349 0.00847 0.75 0.9246 0.9892 1357605 CBMicro_026936 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3ccccc3I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C19 compound treatment 0.349 0.00571 0.47 0.347 0.00647 0.57 0.7405 0.9955 1524634 CBMicro_026937 CC1=CC(C)(C)N(C(=O)CN2C(=O)CCC2=O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C20 compound treatment 0.351 0.00771 0.64 0.344 0.00347 0.31 0.67 0.9435 1939067 CBMicro_026938 COc1ccc(cc1)C2C3C(ON2c4ccccc4)C(=O)N(C3=O)c5ccc(F)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C21 compound treatment 0.343 -2.9E-4 -0.02 0.332 -0.00853 -0.76 -0.5517 -0.7293 1250355 CBMicro_026939 CC1(C)Cc2c(CO1)sc3nc(NN)n(c4ccccc4)c(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C22 compound treatment 0.359 0.0157 1.3 0.359 0.0185 1.64 2.0796 0.9937 1939068 CBMicro_026940 Cc1cc2nc(NCCCO)n(CC(=O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C23 positive control 0.084 -0.259 -21.53 0.087 -0.254 -22.47 -31.1088 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 C24 positive control 0.085 -0.258 -21.44 0.09 -0.251 -22.2 -30.8621 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D01 mock treatment 0.342 -0.00129 -0.11 0.345 0.00447 0.4 0.2043 0.4979 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D02 mock treatment 0.35 0.00671 0.56 0.342 0.00147 0.13 0.4859 0.8495 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D03 compound treatment 0.355 0.0117 0.97 0.353 0.0125 1.11 1.4688 0.998 1939069 CBMicro_026941 CCOc1cc(/C=C(\C#N)/c2nc3ccccc3[nH]2)cc(I)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D04 compound treatment 0.347 0.00371 0.31 0.346 0.00547 0.48 0.5605 0.976 1939070 CBMicro_026942 CCOc1ccc(cc1)N2C(=O)CC(NCc3ccc(cc3)S(=O)(=O)N)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D05 compound treatment 0.346 0.00271 0.22 0.346 0.00547 0.48 0.5018 0.9391 1562227 CBMicro_026943 CC(=O)OCC1(COC(C2C1)c3ccccc3OC(=O)C)CC=C2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D06 compound treatment 0.364 0.0207 1.72 0.366 0.0255 2.26 2.8117 0.991 1939071 CBMicro_026944 Cn1c(N)c(/C=N/Nc2ccccc2)c(=O)n(C)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D07 compound treatment 0.352 0.00871 0.72 0.36 0.0195 1.73 1.7313 0.9255 1662449 CBMicro_026945 Nc1nc2CCCCCCc2c(c1C#N)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D08 compound treatment 0.349 0.00571 0.47 0.359 0.0185 1.64 1.4925 0.8759 1939072 CBMicro_026946 CCOC(=O)c1c(C)c(C)sc1/N=C/c2c(O)c(cc3oc4CCCCc4c23)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D09 compound treatment 0.353 0.00971 0.81 0.352 0.0115 1.02 1.2887 0.9934 1939073 CBMicro_026947 COC(=O)c1cc(ccc1Cl)c2ccc(/C=N/n3cnnc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D10 compound treatment 0.354 0.0107 0.89 0.342 0.00147 0.13 0.7207 0.8021 1939074 CBMicro_026948 CCOc1ccc(NC(=O)C(=O)NC(C)c2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D11 compound treatment 0.349 0.00571 0.47 0.341 4.69E-4 0.04 0.3646 0.7661 1939075 CBMicro_026949 COC(=O)c1ccc(/C=N/Nc2nncc(n2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D12 compound treatment 0.342 -0.00129 -0.11 0.349 0.00847 0.75 0.4549 0.6001 1385531 CBMicro_026950 Cc1ccc(cc1C)C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D13 compound treatment 0.343 -2.9E-4 -0.02 0.352 0.0115 1.02 0.7016 0.6901 1780005 CBMicro_026951 COc1cc(F)ccc1S(=O)(=O)n2cnc3cc(ccc23)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D14 compound treatment 0.351 0.00771 0.64 0.355 0.0145 1.28 1.3593 0.9485 1721017 CBMicro_026952 Cc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D15 compound treatment 0.348 0.00471 0.39 0.337 -0.00353 -0.31 0.0552 0.1102 1705701 CBMicro_026953 COc1cc(OC)cc(c1)C(=O)N2CCN(C)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D16 compound treatment 0.346 0.00271 0.22 0.357 0.0165 1.46 1.1911 0.8066 1648885 CBMicro_026954 Clc1cccc(c1)N2CCN(CC2)C(=O)c3ccccc3I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D17 compound treatment 0.366 0.0227 1.89 0.358 0.0175 1.55 2.4278 0.9952 1939076 CBMicro_026955 CN(C)/N=C/c1ccc(o1)c2ccc(Cl)c(c2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D18 compound treatment 0.351 0.00771 0.64 0.344 0.00347 0.31 0.67 0.9435 1779297 CBMicro_026956 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4ccc(cc4)[N+](=O)[O-])c(=O)n2C1c5ccc6OCOc6c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D19 compound treatment 0.346 0.00271 0.22 0.344 0.00347 0.31 0.3764 0.9882 1939077 CBMicro_026957 CC(=O)c1c(C)nn2c1n(C)c3ccccc32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D20 compound treatment 0.356 0.0127 1.06 0.361 0.0205 1.81 2.0288 0.9668 1489434 CBMicro_026958 COC(=O)COc1ccc(cc1)C(=O)CSc2nc3cc(OC)ccc3n2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D21 compound treatment 0.354 0.0107 0.89 0.348 0.00747 0.66 1.0967 0.9894 1939078 CBMicro_026959 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)Nc3ccc(Br)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D22 compound treatment 0.348 0.00471 0.39 0.347 0.00647 0.57 0.6818 0.9826 1658671 CBMicro_026960 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D23 positive control 0.082 -0.261 -21.69 0.084 -0.257 -22.73 -31.4142 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 D24 positive control 0.086 -0.257 -21.36 0.09 -0.251 -22.2 -30.8034 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E01 mock treatment 0.339 -0.00429 -0.36 0.334 -0.00653 -0.58 -0.6611 -0.9728 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E02 mock treatment 0.351 0.00771 0.64 0.343 0.00247 0.22 0.6073 0.8978 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E03 compound treatment 0.401 0.0577 4.79 0.348 0.00747 0.66 3.8558 0.7972 1939079 CBMicro_026961 O=C(CN1C(=O)/C(=N/NC(=O)C(=O)NCc2ccccc2)/c3ccccc13)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E04 compound treatment 0.344 7.1E-4 0.06 0.343 0.00247 0.22 0.1964 0.8666 1939080 CBMicro_026962 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C/c3c[nH]c4ccccc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E05 compound treatment 0.343 -2.9E-4 -0.02 0.348 0.00747 0.66 0.451 0.6809 1939081 CBMicro_026963 [O-][N+](=O)c1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E06 compound treatment 0.366 0.0227 1.89 0.348 0.00747 0.66 1.8012 0.9014 1939082 CBMicro_026964 Oc1cccc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E07 compound treatment 0.372 0.0287 2.38 0.366 0.0255 2.26 3.2814 0.9996 1939083 CBMicro_026965 Fc1ccc(/C=N/NC(=O)c2cccc(Br)c2)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E08 compound treatment 0.358 0.0147 1.22 0.353 0.0125 1.11 1.6449 0.9988 1780063 CBMicro_026966 Cc1sc(cc1[N+](=O)[O-])c2c(C#N)c(N)nc3CCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E09 compound treatment 0.492 0.149 12.35 0.483 0.142 12.63 17.6576 0.9999 1939084 CBMicro_026967 OC(=O)CCCN1C(=O)/C(=C/c2ccccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E10 compound treatment 0.36 0.0167 1.39 0.358 0.0175 1.55 2.0756 0.9985 1587857 CBMicro_026968 Oc1ccc(NC(=O)C(c2ccccc2)c3ccccc3)cc1c4nc5ccccc5s4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E11 compound treatment 0.355 0.0117 0.97 0.356 0.0155 1.37 1.6567 0.9858 1153217 CBMicro_026969 COc1ccc2[nH]c3C(=O)CCCc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E12 compound treatment 0.342 -0.00129 -0.11 0.345 0.00447 0.4 0.2043 0.4979 1423387 CBMicro_026970 CC(N1C(=O)c2ccccc2C1=O)C(=O)NCc3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E13 compound treatment 0.344 7.1E-4 0.06 0.347 0.00647 0.57 0.447 0.7757 1541296 CBMicro_026971 CCN(CC)c1ccc(C=c2sc3nc4ccccc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E14 compound treatment 0.34 -0.00329 -0.27 0.338 -0.00253 -0.22 -0.3518 -0.9952 1473242 CBMicro_026972 Clc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E15 compound treatment 0.355 0.0117 0.97 0.356 0.0155 1.37 1.6567 0.9858 1399085 CBMicro_026973 Cc1cccc(c1)C2(CC2C(=O)NCc3ccco3)c4cccc(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E16 compound treatment 0.35 0.00671 0.56 0.35 0.00947 0.84 0.9872 0.9802 1092193 CBMicro_026974 Cn1c(=O)n(C)c2nc(N)c(C#N)cc2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E17 compound treatment 0.349 0.00571 0.47 0.341 4.69E-4 0.04 0.3646 0.7661 1431026 CBMicro_026975 COC(=O)C1C(C(C(=O)OC)C(C)(O)CC1=O)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E18 compound treatment 0.372 0.0287 2.38 0.369 0.0285 2.52 3.4693 0.9996 1939085 CBMicro_026976 CN(C)N/C=C/1\C(=O)N(C(=O)c2ccccc12)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E19 compound treatment 0.378 0.0347 2.88 0.366 0.0255 2.26 3.6336 0.9927 1319460 CBMicro_026977 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)c(Cl)c5)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E20 compound treatment 0.35 0.00671 0.56 0.345 0.00447 0.4 0.6739 0.986 1603670 CBMicro_026978 Cc1cc(NCc2cccnc2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E21 compound treatment 0.348 0.00471 0.39 0.345 0.00447 0.4 0.5565 1.0 1939086 CBMicro_026979 CC1(C)Cc2c(CO1)sc3[nH]c(=O)n(c4ccccc4)c(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E22 compound treatment 0.354 0.0107 0.89 0.351 0.0105 0.93 1.2847 0.9998 1939087 CBMicro_026980 Fc1ccc(NC2CC(=O)N(C2=O)c3ccccc3C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E23 positive control 0.083 -0.26 -21.61 0.083 -0.258 -22.82 -31.4181 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 E24 positive control 0.087 -0.256 -21.28 0.091 -0.25 -22.11 -30.682 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F01 mock treatment 0.339 -0.00429 -0.36 0.337 -0.00353 -0.31 -0.4731 -0.9979 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F02 mock treatment 0.344 7.1E-4 0.06 0.34 -5.31E-4 -0.05 0.0084 0.111 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F03 compound treatment 0.345 0.00171 0.14 0.346 0.00547 0.48 0.4431 0.8773 1268188 CBMicro_026981 CCOC(=O)C1=C(C)NC(=S)NC1c2cc(OC)c(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F04 compound treatment 0.347 0.00371 0.31 0.342 0.00147 0.13 0.3098 0.9266 1334245 CBMicro_026982 Oc1c(CC(=O)NCc2ccc(Cl)cc2)c(=O)[nH]c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F05 compound treatment 0.344 7.1E-4 0.06 0.355 0.0145 1.28 0.9483 0.7388 1939088 CBMicro_026983 Clc1cccc(c1)c2ccc(/C=N/n3cnnc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F06 compound treatment 0.344 7.1E-4 0.06 0.351 0.0105 0.93 0.6977 0.7505 1450402 CBMicro_026984 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F07 compound treatment 0.352 0.00871 0.72 0.361 0.0205 1.81 1.794 0.9187 1939089 CBMicro_026985 Oc1ccc(/C=N/Nc2nncc(n2)c3ccccc3)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F08 compound treatment 0.351 0.00771 0.64 0.354 0.0135 1.19 1.2966 0.9573 1939090 CBMicro_026986 NS(=O)(=O)c1ccc(CNC2CC(=O)N(C2=O)c3cccc(Br)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F09 compound treatment 0.358 0.0147 1.22 0.361 0.0205 1.81 2.1462 0.9815 1139718 CBMicro_026987 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3O)c(=O)n2C1c4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F10 compound treatment 0.408 0.0647 5.37 0.408 0.0675 5.98 8.0266 0.9986 1939091 CBMicro_026988 Oc1ccccc1N/C=C/2\Sc3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F11 compound treatment 0.371 0.0277 2.3 0.383 0.0425 3.76 4.288 0.9721 1261220 CBMicro_026989 Cc1nn(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)c(C)c1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F12 compound treatment 0.349 0.00571 0.47 0.331 -0.00953 -0.84 -0.2621 -0.2706 1939092 CBMicro_026990 Oc1ccccc1/C=N/c2nc3ccccc3n2Cc4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F13 compound treatment 0.373 0.0297 2.47 0.358 0.0175 1.55 2.8387 0.9748 1939093 CBMicro_026991 COc1cccc(/C=N/NC(=O)Cn2c(nc3ccccc23)c4nonc4N)c1OCc5ccc(Cl)cc5Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F14 compound treatment 0.377 0.0337 2.8 0.371 0.0305 2.7 3.8882 0.9998 1939094 CBMicro_026992 O=C/1N(C(=O)c2ccccc2\C1=C/N3CCCCC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F15 compound treatment 0.354 0.0107 0.89 0.345 0.00447 0.4 0.9087 0.9336 1939095 CBMicro_026993 O=C(NCc1ccccn1)C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F16 compound treatment 0.355 0.0117 0.97 0.35 0.00947 0.84 1.2808 0.9973 1360431 CBMicro_026994 Cc1nn2c(c1C(=O)NN)n(C)c3ccccc32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F17 compound treatment 0.354 0.0107 0.89 0.346 0.00547 0.48 0.9714 0.9593 1939096 CBMicro_026995 Cc1ccc(cc1)C(=O)N/C(=C/c2cccnc2)/C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F18 compound treatment 0.355 0.0117 0.97 0.342 0.00147 0.13 0.7794 0.7947 1351444 CBMicro_026996 Cc1ccc(c2csc(N)n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F19 compound treatment 0.363 0.0197 1.64 0.371 0.0305 2.7 3.0664 0.9712 1189588 CBMicro_026997 O=c1c(=Cc2c[nH]nc2c3ccccc3)sc4nc5ccccc5n14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F20 compound treatment 0.347 0.00371 0.31 0.347 0.00647 0.57 0.6231 0.9575 1692150 CBMicro_026998 COc1cc(OC)cc(c1)C(=O)Nc2cccc(NC(=O)C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F21 compound treatment 0.349 0.00571 0.47 0.342 0.00147 0.13 0.4272 0.8691 1187961 CBMicro_026999 COc1ccc(C(=O)Nc2ccc(Br)cc2F)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F22 compound treatment 0.346 0.00271 0.22 0.337 -0.00353 -0.31 -0.0622 -0.1614 1487372 CBMicro_027000 COc1ccc(cc1)C(=O)CC(C2CCCCC2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F23 positive control 0.084 -0.259 -21.53 0.089 -0.252 -22.29 -30.9834 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 F24 positive control 0.088 -0.255 -21.19 0.091 -0.25 -22.11 -30.6233 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G01 mock treatment 0.335 -0.00829 -0.69 0.335 -0.00553 -0.49 -0.8333 -0.9862 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G02 mock treatment 0.34 -0.00329 -0.27 0.336 -0.00453 -0.4 -0.4771 -0.9824 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G03 compound treatment 0.338 -0.00529 -0.44 0.341 4.69E-4 0.04 -0.2812 -0.6374 1939097 CBMicro_027001 COc1cc(ccc1OC(=O)CN2C(=O)c3ccccc3C2=O)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G04 compound treatment 0.363 0.0197 1.64 0.369 0.0285 2.52 2.941 0.978 1621640 CBMicro_027002 Fc1ccc(cc1)c2csc(Nc3ccc4OCOc4c3)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G05 compound treatment 0.345 0.00171 0.14 0.344 0.00347 0.31 0.3177 0.9384 1939098 CBMicro_027003 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G06 compound treatment 0.344 7.1E-4 0.06 0.344 0.00347 0.31 0.259 0.8276 1939099 CBMicro_027004 COc1cc(/C=N/NC(=O)N)ccc1OCC(=O)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G07 compound treatment 0.357 0.0137 1.14 0.355 0.0145 1.28 1.7115 0.9982 1939100 CBMicro_027005 CCOc1ccc(cc1)N(CC(=O)Nc2cccc(c2)C(=O)C)S(=O)(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G08 compound treatment 0.341 -0.00229 -0.19 0.347 0.00647 0.57 0.2709 0.4485 1416539 CBMicro_027006 COC(=O)c1ccc(NC(=O)c2ccc3nccnc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G09 compound treatment 0.332 -0.0113 -0.94 0.328 -0.0125 -1.11 -1.4481 -0.9964 1939101 CBMicro_027007 C/C(=N/NC(=O)Cc1ccc(Cl)cc1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G10 compound treatment 0.354 0.0107 0.89 0.355 0.0145 1.28 1.5354 0.984 1419028 CBMicro_027008 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G11 compound treatment 0.431 0.0877 7.28 0.443 0.102 9.08 11.5701 0.994 1939102 CBMicro_027009 Cc1ccc(cc1)N2NC(=O)/C(=C/c3ccc(O)c(O)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G12 compound treatment 0.371 0.0277 2.3 0.376 0.0355 3.14 3.8493 0.9882 1939103 CBMicro_027010 CCCCc1ccc(/C=C\2/C(=O)ON=C2c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G13 compound treatment 0.47 0.127 10.52 0.486 0.145 12.89 16.5541 0.9949 1939104 CBMicro_027011 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=C(\C#N)/C(=O)N3CCCCC3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G14 compound treatment 0.346 0.00271 0.22 0.341 4.69E-4 0.04 0.1884 0.8238 1939105 CBMicro_027012 COc1cccc(c1)N2C(=O)CC(NCc3ccc(cc3)S(=O)(=O)N)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G15 compound treatment 0.346 0.00271 0.22 0.342 0.00147 0.13 0.2511 0.9662 1007322 CBMicro_027013 CCOC(=O)c1[nH]c(C)c(C(=O)O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G16 compound treatment 0.351 0.00771 0.64 0.355 0.0145 1.28 1.3593 0.9485 1496641 CBMicro_027014 COc1ccc(cc1)C2SCCN2S(=O)(=O)c3ccc4ccccc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G17 compound treatment 0.336 -0.00729 -0.61 0.346 0.00547 0.48 -0.0853 -0.11 1939106 CBMicro_027015 OC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3N=C1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G18 compound treatment 0.435 0.0917 7.61 0.388 0.0475 4.21 8.3583 0.9609 1705939 CBMicro_027016 COc1ccc(NCC(O)Cn2c3ccc(Br)cc3c4cc(Br)ccc24)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G19 compound treatment 0.335 -0.00829 -0.69 0.344 0.00347 0.31 -0.2693 -0.3573 1939107 CBMicro_027017 O=C1N(C(=O)c2ccccc12)c3cccc(c3)S(=O)(=O)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G20 compound treatment 0.355 0.0117 0.97 0.355 0.0145 1.28 1.5941 0.9907 1471788 CBMicro_027018 CCCCn1c2nc(C)c(C(=O)OC)n2c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G21 compound treatment 0.34 -0.00329 -0.27 0.344 0.00347 0.31 0.0242 0.0589 1482929 CBMicro_027019 CC1(C)Cc2c(C#N)c(=O)[nH]c(c3ccccc3)c2CO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G22 compound treatment 0.388 0.0447 3.71 0.382 0.0415 3.68 5.2232 1.0 1709409 CBMicro_027020 CCOc1ccc(cc1)C(=O)Nc2cccc(NC(=O)c3cccc4ccccc34)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G23 positive control 0.085 -0.258 -21.44 0.087 -0.254 -22.47 -31.0501 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 G24 positive control 0.09 -0.253 -21.03 0.093 -0.248 -21.94 -30.3805 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H01 mock treatment 0.334 -0.00929 -0.77 0.337 -0.00353 -0.31 -0.7667 -0.9211 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H02 mock treatment 0.345 0.00171 0.14 0.337 -0.00353 -0.31 -0.1209 -0.3519 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H03 compound treatment 0.337 -0.00629 -0.52 0.339 -0.00153 -0.14 -0.4652 -0.8622 1939108 CBMicro_027021 COc1ccc(/C=C/C(=O)Nc2nc3ccccc3n2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H04 compound treatment 0.34 -0.00329 -0.27 0.339 -0.00153 -0.14 -0.2891 -0.9479 1516767 CBMicro_027022 Oc1c(CC(=O)NCCc2ccccc2)c(=O)[nH]c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H05 compound treatment 0.341 -0.00229 -0.19 0.346 0.00547 0.48 0.2083 0.4 1939109 CBMicro_027023 OC(=O)COc1ccc(Br)cc1/C=N/NC(=O)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H06 compound treatment 0.336 -0.00729 -0.61 0.344 0.00347 0.31 -0.2106 -0.3102 1939110 CBMicro_027024 O=C(NCc1ccncc1)C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H07 compound treatment 0.542 0.199 16.5 0.551 0.21 18.65 24.854 0.9981 1939111 CBMicro_027025 Nc1ccccc1N/C=C/2\N=C(OC2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H08 compound treatment 0.336 -0.00729 -0.61 0.34 -5.31E-4 -0.05 -0.4613 -0.7598 1939112 CBMicro_027026 CC(=O)c1c(C)nn2c1n(CCN3CCCCC3)c4ccccc42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H09 compound treatment 0.345 0.00171 0.14 0.337 -0.00353 -0.31 -0.1209 -0.3519 1939113 CBMicro_027027 Cc1cc(C)c2nc(NC(=O)c3ccc(F)c(F)c3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H10 compound treatment 0.344 7.1E-4 0.06 0.334 -0.00653 -0.58 -0.3676 -0.6319 1178082 CBMicro_027028 CCc1ccc(cc1)C(=O)CC(C2CCCCC2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H11 compound treatment 0.34 -0.00329 -0.27 0.345 0.00447 0.4 0.0869 0.1806 1405180 CBMicro_027029 COc1cccc(c1)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Br)cc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H12 compound treatment 0.339 -0.00429 -0.36 0.341 4.69E-4 0.04 -0.2225 -0.6204 1781053 CBMicro_027030 CN1CCN(CC1)C(=O)c2ccc(Cl)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H13 compound treatment 0.343 -2.9E-4 -0.02 0.356 0.0155 1.37 0.9523 0.6946 1306059 CBMicro_027031 Nc1nc2CCCCCCc2c(c3ccc(Br)s3)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H14 compound treatment 0.337 -0.00629 -0.52 0.34 -5.31E-4 -0.05 -0.4026 -0.7677 1532109 CBMicro_027032 O=C(NCc1ccccc1)c2ccc3nccnc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H15 compound treatment 0.379 0.0357 2.96 0.379 0.0385 3.41 4.5069 0.9976 1939114 CBMicro_027033 CCc1ccc(/C=C(/C#N)\C(=O)N)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H16 compound treatment 0.368 0.0247 2.05 0.37 0.0295 2.61 3.2972 0.9929 1939115 CBMicro_027034 CCOc1ccc(Nc2nc(cs2)c3cccs3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H17 compound treatment 0.339 -0.00429 -0.36 0.346 0.00547 0.48 0.0908 0.151 1939116 CBMicro_027035 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4cc(ccc4C)[N+](=O)[O-])c(=O)n2C1c5ccc6OCOc6c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H18 compound treatment 0.361 0.0177 1.47 0.348 0.00747 0.66 1.5076 0.9351 1331507 CBMicro_027036 Cc1ccc(cc1C)c2csc(Nc3cccc4ccccc34)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H19 compound treatment 0.343 -2.9E-4 -0.02 0.341 4.69E-4 0.04 0.0123 0.2568 1421773 CBMicro_027037 COc1cc(OC)cc(c1)C(=O)NC2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H20 compound treatment 0.522 0.179 14.84 0.532 0.191 16.97 22.4893 0.9978 1939117 CBMicro_027038 OC(=O)c1cc(ccc1Cl)c2ccc(/C=N/Nc3ccc(Cl)c(Cl)c3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H21 compound treatment 0.349 0.00571 0.47 0.354 0.0135 1.19 1.1792 0.9182 1433316 CBMicro_027039 ON=C(c1nc2ccccc2[nH]1)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H22 compound treatment 0.344 7.1E-4 0.06 0.339 -0.00153 -0.14 -0.0543 -0.367 1939118 CBMicro_027040 CCOC(=O)C1CCN(CC1)C2CC(=O)N(C2=O)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H23 positive control 0.086 -0.257 -21.36 0.089 -0.252 -22.29 -30.866 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 H24 positive control 0.092 -0.251 -20.86 0.095 -0.246 -21.76 -30.1378 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I01 mock treatment 0.345 0.00171 0.14 0.348 0.00747 0.66 0.5684 0.8396 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I02 mock treatment 0.349 0.00571 0.47 0.343 0.00247 0.22 0.4899 0.9383 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I03 compound treatment 0.353 0.00971 0.81 0.355 0.0145 1.28 1.4767 0.975 1939119 CBMicro_027041 COC(=O)CN(c1ccc(Cl)cc1C)S(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I04 compound treatment 0.396 0.0527 4.38 0.375 0.0345 3.05 5.2542 0.9846 1939120 CBMicro_027042 NC(=S)NN=C1c2cc(ccc2-c3ccc(cc13)S(=O)(=O)NCc4ccco4)S(=O)(=O)NCc5ccco5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I05 compound treatment 0.352 0.00871 0.72 0.35 0.00947 0.84 1.1046 0.9973 1939121 CBMicro_027043 CC(C)NC(=O)CN(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I06 compound treatment 0.348 0.00471 0.39 0.347 0.00647 0.57 0.6818 0.9826 1218858 CBMicro_027044 CCOC(=O)c1c(NC(=O)c2ccc(C)cc2)scc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I07 compound treatment 0.345 0.00171 0.14 0.319 -0.0215 -1.91 -1.2489 -0.6527 1939122 CBMicro_027045 Oc1cc(OCC=C)ccc1/C=N/NC(=O)CSc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I08 compound treatment 0.352 0.00871 0.72 0.346 0.00547 0.48 0.854 0.9811 1435998 CBMicro_027046 COc1ccc(cc1OC)c2nnc(NC(=O)c3ccccc3OC)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I09 compound treatment 0.344 7.1E-4 0.06 0.353 0.0125 1.11 0.823 0.7438 1939123 CBMicro_027047 Cc1cc(C)cc(/N=C/c2ccc(OC3CSC3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I10 compound treatment 0.353 0.00971 0.81 0.33 -0.0105 -0.93 -0.09 -0.0729 1149129 CBMicro_027048 Cc1ccc(cc1C)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I11 compound treatment 0.343 -2.9E-4 -0.02 0.351 0.0105 0.93 0.639 0.6885 1524430 CBMicro_027049 Cc1nnc2c3c4CC(C)(C)OCc4sc3nc(c5ccccc5)n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I12 compound treatment 0.339 -0.00429 -0.36 0.344 0.00347 0.31 -0.0345 -0.0733 1939124 CBMicro_027050 COc1ccc(C(=O)NC2=NCCS2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I13 compound treatment 0.343 -2.9E-4 -0.02 0.357 0.0165 1.46 1.015 0.6953 1122069 CBMicro_027051 CC1(C)CC(=O)c2c(c3ccccc3)c4c(=O)[nH]c(=O)[nH]c4nc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I14 compound treatment 0.348 0.00471 0.39 0.34 -5.31E-4 -0.05 0.2432 0.6175 1939125 CBMicro_027052 CCN(CC)c1ccc(/C=N/Nc2nncc(n2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I15 compound treatment 0.399 0.0557 4.62 0.399 0.0585 5.18 6.9343 0.9984 1939126 CBMicro_027053 Fc1cccc(c1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I16 compound treatment 0.346 0.00271 0.22 0.342 0.00147 0.13 0.2511 0.9662 1939127 CBMicro_027054 C(=N/n1cnnc1)\c2c[nH]nc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I17 compound treatment 0.348 0.00471 0.39 0.358 0.0175 1.55 1.3712 0.8587 1939128 CBMicro_027055 Nc1nccc(Nc2ccc(F)cc2)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I18 compound treatment 0.358 0.0147 1.22 0.356 0.0155 1.37 1.8329 0.9983 1939129 CBMicro_027056 CCCOc1ccc(cc1)N2C(=O)CC(N3CCC(CC3)C(=O)OCC)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I19 compound treatment 0.346 0.00271 0.22 0.35 0.00947 0.84 0.7524 0.8661 1939130 CBMicro_027057 Cc1ccc(cc1)S(=O)(=O)C(CC(=O)c2ccccc2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I20 compound treatment 0.341 -0.00229 -0.19 0.354 0.0135 1.19 0.7096 0.5871 1130388 CBMicro_027058 Clc1c(sc2ccccc12)C(=O)Nc3nnc(s3)c4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I21 compound treatment 0.36 0.0167 1.39 0.367 0.0265 2.35 2.6396 0.9686 1550755 CBMicro_027059 CCc1ccc(s1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I22 compound treatment 0.414 0.0707 5.87 0.417 0.0765 6.78 8.9428 0.9974 1352410 CBMicro_027060 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(O)c3)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I23 positive control 0.085 -0.258 -21.44 0.089 -0.252 -22.29 -30.9247 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 I24 positive control 0.09 -0.253 -21.03 0.095 -0.246 -21.76 -30.2552 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J01 mock treatment 0.333 -0.0103 -0.85 0.325 -0.0155 -1.38 -1.5773 -0.9737 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J02 mock treatment 0.347 0.00371 0.31 0.349 0.00847 0.75 0.7485 0.9226 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J03 compound treatment 0.347 0.00371 0.31 0.349 0.00847 0.75 0.7485 0.9226 1939131 CBMicro_027061 CCOC(=O)N1CCN(CC1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J04 compound treatment 0.354 0.0107 0.89 0.351 0.0105 0.93 1.2847 0.9998 1939132 CBMicro_027062 CCOC(=O)C(CC)C(=NNC(=O)c1ccc(cc1)[N+](=O)[O-])C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J05 compound treatment 0.356 0.0127 1.06 0.357 0.0165 1.46 1.7781 0.9873 1504325 CBMicro_027063 CC1CC(=C)CC(O1)c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J06 compound treatment 0.365 0.0217 1.8 0.352 0.0115 1.02 1.9931 0.9633 1939133 CBMicro_027064 CC1(CC(=O)N/N=C/c2cc(Br)c(O)cc2O)OCCO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J07 compound treatment 0.345 0.00171 0.14 0.349 0.00847 0.75 0.6311 0.8262 1939134 CBMicro_027065 NS(=O)(=O)c1ccc(CNC2CC(=O)N(CCc3ccccc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J08 compound treatment 0.35 0.00671 0.56 0.344 0.00347 0.31 0.6112 0.9607 1939135 CBMicro_027066 Cc1ccc(Br)cc1S(=O)(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J09 compound treatment 0.342 -0.00129 -0.11 0.327 -0.0135 -1.2 -0.9237 -0.7672 1778457 CBMicro_027067 COc1ccc(cc1)C(C[N+](=O)[O-])c2c[nH]c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J10 compound treatment 0.408 0.0647 5.37 0.41 0.0695 6.16 8.1519 0.9977 1939136 CBMicro_027068 Clc1ccc(cc1)C(=O)CSC2=NCCS2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J11 compound treatment 0.36 0.0167 1.39 0.356 0.0155 1.37 1.9503 1.0 1939137 CBMicro_027069 COC(=O)C1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J12 compound treatment 0.347 0.00371 0.31 0.349 0.00847 0.75 0.7485 0.9226 1416494 CBMicro_027070 COc1ccc(NC(=O)c2cc3cccc(OC)c3oc2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J13 compound treatment 0.362 0.0187 1.55 0.351 0.0105 0.93 1.7543 0.9697 1939138 CBMicro_027071 CC(=O)c1nc2cc(ccc2n1Cc3ccccc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J14 compound treatment 0.482 0.139 11.52 0.475 0.134 11.92 16.5692 0.9999 1939139 CBMicro_027072 O=C/1NC(=S)S\C1=C\c2ccccc2OCC#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J15 compound treatment 0.35 0.00671 0.56 0.35 0.00947 0.84 0.9872 0.9802 1939140 CBMicro_027073 COC(=O)C1(CCCC1)S(=O)(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J16 compound treatment 0.55 0.207 17.16 0.568 0.227 20.16 26.3889 0.9968 1939141 CBMicro_027074 [O-][N+](=O)c1cc(/C=C/2\SC(=S)NC2=O)ccc1N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J17 compound treatment 0.325 -0.0183 -1.52 0.315 -0.0255 -2.26 -2.6736 -0.9812 1939142 CBMicro_027075 c1nc2ccccc2n1c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J18 compound treatment 0.383 0.0397 3.3 0.374 0.0335 2.97 4.4284 0.9986 1939143 CBMicro_027076 OCCNC(=O)c1ccc2nc3c4ccccc4c5ccccc5c3nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J19 compound treatment 0.352 0.00871 0.72 0.351 0.0105 0.93 1.1673 0.9924 1455687 CBMicro_027077 COc1ccc2n(C)c(SCC(=O)c3ccccc3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J20 compound treatment 0.351 0.00771 0.64 0.352 0.0115 1.02 1.1713 0.9751 1939144 CBMicro_027078 COc1ccccc1C(=O)N/C(=C\c2ccc(Br)cc2)/c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J21 compound treatment 0.365 0.0217 1.8 0.348 0.00747 0.66 1.7425 0.9075 1939145 CBMicro_027079 COc1ccc(CCNC2CC(=O)N(C2=O)c3ccc(F)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J22 compound treatment 0.349 0.00571 0.47 0.362 0.0215 1.9 1.6805 0.8571 1939146 CBMicro_027080 Cc1ccc(cc1)N2C(=O)/C(=C/N3CCOCC3)/c4ccccc4C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J23 positive control 0.086 -0.257 -21.36 0.089 -0.252 -22.29 -30.866 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 J24 positive control 0.091 -0.252 -20.94 0.094 -0.247 -21.85 -30.2592 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K01 mock treatment 0.338 -0.00529 -0.44 0.344 0.00347 0.31 -0.0932 -0.1738 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K02 mock treatment 0.344 7.1E-4 0.06 0.339 -0.00153 -0.14 -0.0543 -0.367 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K03 compound treatment 0.348 0.00471 0.39 0.346 0.00547 0.48 0.6192 0.9943 1939147 CBMicro_027081 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccco4)C(=O)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K04 compound treatment 0.35 0.00671 0.56 0.345 0.00447 0.4 0.6739 0.986 1156929 CBMicro_027082 CCOc1ccc(NC(=O)CN(Cc2ccccc2)S(=O)(=O)c3ccc(OC)c(OC)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K05 compound treatment 0.348 0.00471 0.39 0.345 0.00447 0.4 0.5565 1.0 1242491 CBMicro_027083 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(OCC)cc2)S(=O)(=O)c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K06 compound treatment 0.349 0.00571 0.47 0.347 0.00647 0.57 0.7405 0.9955 1939148 CBMicro_027084 Cc1sc(cc1Br)c2c(C#N)c(N)nc3CCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K07 compound treatment 0.347 0.00371 0.31 0.338 -0.00253 -0.22 0.0591 0.1552 1591262 CBMicro_027085 Cc1ccc(cc1)c2csc3[nH]c(=S)n(CC=C)c(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K08 compound treatment 0.352 0.00871 0.72 0.355 0.0145 1.28 1.418 0.9633 1939149 CBMicro_027086 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)CCC3=O)c4ccccc24)S1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K09 compound treatment 0.339 -0.00429 -0.36 0.341 4.69E-4 0.04 -0.2225 -0.6204 1939150 CBMicro_027087 O/N=C/c1ccc(cn1)C(=O)NCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K10 compound treatment 0.353 0.00971 0.81 0.354 0.0135 1.19 1.414 0.9817 1242803 CBMicro_027088 Cc1ccc2cc(C)c(NCc3ccccn3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K11 compound treatment 0.358 0.0147 1.22 0.34 -5.31E-4 -0.05 0.8302 0.6793 1939151 CBMicro_027089 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K12 compound treatment 0.349 0.00571 0.47 0.342 0.00147 0.13 0.4272 0.8691 1343194 CBMicro_027090 COc1ccc(C(=O)NCC2CCCO2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K13 compound treatment 0.348 0.00471 0.39 0.347 0.00647 0.57 0.6818 0.9826 1256513 CBMicro_027091 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(C)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K14 compound treatment 0.344 7.1E-4 0.06 0.349 0.00847 0.75 0.5724 0.7603 1443921 CBMicro_027092 CCOC(=O)c1c(NC(=O)c2ccc(cc2)C(=O)c3ccccc3)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K15 compound treatment 0.345 0.00171 0.14 0.35 0.00947 0.84 0.6937 0.8151 1939152 CBMicro_027093 CSc1nnc2n(C)c(=O)c3c4CC(C)(C)OCc4sc3n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K16 compound treatment 0.356 0.0127 1.06 0.346 0.00547 0.48 1.0888 0.9377 1939153 CBMicro_027094 Oc1ccc2cccc(/C=C/3\C(=O)Oc4ccccc4C3=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K17 compound treatment 0.349 0.00571 0.47 0.354 0.0135 1.19 1.1792 0.9182 1343267 CBMicro_027095 Nc1c(C#N)c2CCCCn2c1C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K18 compound treatment 0.35 0.00671 0.56 0.356 0.0155 1.37 1.3632 0.9213 1629397 CBMicro_027096 COc1cc(F)ccc1S(=O)(=O)N2CCC(C)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K19 compound treatment 0.363 0.0197 1.64 0.368 0.0275 2.43 2.8784 0.9813 1939154 CBMicro_027097 O=C(Nc1ccc(cc1)N2CCCCC2)/C=C/c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K20 compound treatment 0.393 0.0497 4.13 0.391 0.0505 4.47 6.0808 0.9992 1939155 CBMicro_027098 C/C(=N\NC(=O)c1cc2ccccc2cc1O)/c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K21 compound treatment 0.343 -2.9E-4 -0.02 0.352 0.0115 1.02 0.7016 0.6901 1271909 CBMicro_027099 Cc1c(N(CC(=O)Nc2ccc(C)cc2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K22 compound treatment 0.346 0.00271 0.22 0.352 0.0115 1.02 0.8778 0.8432 1503162 CBMicro_027100 COc1ccc(OC)c(c1)N(CC(=O)N2CCc3ccccc3C2)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K23 positive control 0.087 -0.256 -21.28 0.09 -0.251 -22.2 -30.7447 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 K24 positive control 0.092 -0.251 -20.86 0.095 -0.246 -21.76 -30.1378 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L01 mock treatment 0.339 -0.00429 -0.36 0.343 0.00247 0.22 -0.0972 -0.2324 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L02 mock treatment 0.346 0.00271 0.22 0.344 0.00347 0.31 0.3764 0.9882 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L03 compound treatment 0.345 0.00171 0.14 0.344 0.00347 0.31 0.3177 0.9384 1413611 CBMicro_027101 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc4ccccc4c3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L04 compound treatment 0.371 0.0277 2.3 0.366 0.0255 2.26 3.2227 1.0 1939156 CBMicro_027102 COc1ccccc1NC2C=CC(=O)C2Nc3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L05 compound treatment 0.344 7.1E-4 0.06 0.344 0.00347 0.31 0.259 0.8276 1458425 CBMicro_027103 COc1cccc2cc(C(=O)N)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L06 compound treatment 0.341 -0.00229 -0.19 0.355 0.0145 1.28 0.7722 0.5957 1939157 CBMicro_027104 Clc1ccccc1N2CCN(CC2)C3CC(=O)N(C3=O)c4cccc(Br)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L07 compound treatment 0.354 0.0107 0.89 0.348 0.00747 0.66 1.0967 0.9894 1442923 CBMicro_027105 COc1ccc(NCc2nc3ccccc3n2Cc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L08 compound treatment 0.373 0.0297 2.47 0.363 0.0225 1.99 3.1521 0.9944 1939158 CBMicro_027106 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3ccc(Cl)cc3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L09 compound treatment 0.358 0.0147 1.22 0.375 0.0345 3.05 3.0235 0.9191 1939159 CBMicro_027107 COc1cccc(NC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L10 compound treatment 0.349 0.00571 0.47 0.354 0.0135 1.19 1.1792 0.9182 1310602 CBMicro_027108 CSc1ccc(cc1)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L11 compound treatment 0.348 0.00471 0.39 0.344 0.00347 0.31 0.4938 0.9929 1939160 CBMicro_027109 COc1cc(/C=N/NC(=O)CC(=O)NC(C)C)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L12 compound treatment 0.347 0.00371 0.31 0.344 0.00347 0.31 0.4351 1.0 1206815 CBMicro_027110 OC(=O)c1ccccc1N2C(=O)C3CC=CCC3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L13 compound treatment 0.371 0.0277 2.3 0.37 0.0295 2.61 3.4733 0.998 1475805 CBMicro_027111 CCOC(=O)c1c(NC(=O)C(C)C)scc1c2ccc(cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L14 compound treatment 0.35 0.00671 0.56 0.337 -0.00353 -0.31 0.1726 0.2701 1939161 CBMicro_027112 COC(=O)C1(CCOCC1)S(=O)(=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L15 compound treatment 0.381 0.0377 3.13 0.37 0.0295 2.61 4.0603 0.9959 1939162 CBMicro_027113 COc1cc(/C=C/2\Sc3ccccc3C2=O)ccc1OCC#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L16 compound treatment 0.349 0.00571 0.47 0.343 0.00247 0.22 0.4899 0.9383 1939163 CBMicro_027114 CC1CC2(CCCC2)N(Cc3ccccc13)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L17 compound treatment 0.353 0.00971 0.81 0.351 0.0105 0.93 1.226 0.9975 1624422 CBMicro_027115 OC(=O)c1cc(ccc1Cl)c2ccc(C=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L18 compound treatment 0.526 0.183 15.17 0.5 0.159 14.13 20.7188 0.9994 1939164 CBMicro_027116 COc1cc(/C=C/2\Sc3ccccc3C2=O)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L19 compound treatment 0.346 0.00271 0.22 0.346 0.00547 0.48 0.5018 0.9391 1703276 CBMicro_027117 CCOC(=O)c1c(NC(=O)c2ccc(C)cc2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L20 compound treatment 0.352 0.00871 0.72 0.348 0.00747 0.66 0.9793 0.999 1939165 CBMicro_027118 Clc1ccc(cc1)N2CCN(CC2)C3CC(=O)N(C3=O)c4cccc(Br)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L21 compound treatment 0.349 0.00571 0.47 0.345 0.00447 0.4 0.6152 0.996 1939166 CBMicro_027119 COc1ccc(C(=O)Nc2ccc(OC)cc2[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L22 compound treatment 0.363 0.0197 1.64 0.355 0.0145 1.28 2.0637 0.9927 1659877 CBMicro_027120 Fc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L23 positive control 0.089 -0.254 -21.11 0.09 -0.251 -22.2 -30.6272 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 L24 positive control 0.092 -0.251 -20.86 0.096 -0.245 -21.67 -30.0751 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M01 mock treatment 0.339 -0.00429 -0.36 0.341 4.69E-4 0.04 -0.2225 -0.6204 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M02 mock treatment 0.343 -2.9E-4 -0.02 0.342 0.00147 0.13 0.075 0.5665 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M03 compound treatment 0.357 0.0137 1.14 0.34 -5.31E-4 -0.05 0.7715 0.6773 1939167 CBMicro_027121 C/C(=N/NC(=O)c1ccc(Cl)cc1)/Cn2nnc(n2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M04 compound treatment 0.349 0.00571 0.47 0.349 0.00847 0.75 0.8659 0.9754 1939168 CBMicro_027122 CCOC(=O)N1CCN(CC1)C2CC(=O)N(C2=O)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M05 compound treatment 0.346 0.00271 0.22 0.346 0.00547 0.48 0.5018 0.9391 1939169 CBMicro_027123 Clc1ccc(CNC=C2C(=O)c3ccccc3C2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M06 compound treatment 0.345 0.00171 0.14 0.358 0.0175 1.55 1.195 0.7687 1348013 CBMicro_027124 CCOc1ccc(cc1)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M07 compound treatment 0.348 0.00471 0.39 0.349 0.00847 0.75 0.8072 0.9538 1939170 CBMicro_027125 COc1ccc(CCNC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)c3ccc(OC)c(OC)c3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M08 compound treatment 0.346 0.00271 0.22 0.345 0.00447 0.4 0.4391 0.9641 1939171 CBMicro_027126 O=c1n2CCSc2nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M09 compound treatment 0.352 0.00871 0.72 0.344 0.00347 0.31 0.7287 0.9274 1525337 CBMicro_027127 Cc1c(NC(=S)NC(C)(C)C)c(=O)n(c2ccccc2)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M10 compound treatment 0.347 0.00371 0.31 0.341 4.69E-4 0.04 0.2471 0.7953 1119326 CBMicro_027128 OCCNC(=O)c1cccc2Cc3cc(I)ccc3-c21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M11 compound treatment 0.361 0.0177 1.47 0.366 0.0255 2.26 2.6356 0.9784 1647037 CBMicro_027129 OC(=O)c1cc2nc(cc(c3ccccc3)n2n1)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M12 compound treatment 0.345 0.00171 0.14 0.354 0.0135 1.19 0.9444 0.7857 1939172 CBMicro_027130 CC/C(=N\NC(=O)N)/C1CC(CC=C1C)C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M13 compound treatment 0.343 -2.9E-4 -0.02 0.352 0.0115 1.02 0.7016 0.6901 1260855 CBMicro_027131 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)Nc3ccc(C)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M14 compound treatment 0.352 0.00871 0.72 0.349 0.00847 0.75 1.042 0.9998 1779272 CBMicro_027132 COc1ccc(cc1)c2nnc(NC(=O)c3ccccc3OC)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M15 compound treatment 0.342 -0.00129 -0.11 0.346 0.00547 0.48 0.267 0.5378 1939173 CBMicro_027133 CSc1nc(C)cc(n1)n2ccc(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M16 compound treatment 0.351 0.00771 0.64 0.361 0.0205 1.81 1.7353 0.9021 1245140 CBMicro_027134 COc1ccc(NC(=O)c2cccc3Cc4cc(I)ccc4-c32)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M17 compound treatment 0.349 0.00571 0.47 0.342 0.00147 0.13 0.4272 0.8691 1939174 CBMicro_027135 COc1ccc(CSC2=NCCN2)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M18 compound treatment 0.353 0.00971 0.81 0.346 0.00547 0.48 0.9127 0.9704 1225191 CBMicro_027136 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M19 compound treatment 0.343 -2.9E-4 -0.02 0.345 0.00447 0.4 0.263 0.6628 1553233 CBMicro_027137 COc1ccc(cc1OC)C(=O)Nc2ccccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M20 compound treatment 0.34 -0.00329 -0.27 0.328 -0.0125 -1.11 -0.9784 -0.8555 1251048 CBMicro_027138 Cc1cccc(c1)S(=O)(=O)N2CCSC2c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M21 compound treatment 0.339 -0.00429 -0.36 0.347 0.00647 0.57 0.1535 0.2275 1271767 CBMicro_027139 COC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3)C(=O)CCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M22 compound treatment 0.348 0.00471 0.39 0.351 0.0105 0.93 0.9325 0.9262 1939175 CBMicro_027140 CC(=C)C1CCC(=C1CC(C)(C)/C=N\n2cnnc2)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M23 positive control 0.089 -0.254 -21.11 0.091 -0.25 -22.11 -30.5646 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 M24 positive control 0.093 -0.25 -20.78 0.097 -0.244 -21.58 -29.9538 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N01 mock treatment 0.351 0.00771 0.64 0.346 0.00547 0.48 0.7953 0.9906 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N02 mock treatment 0.349 0.00571 0.47 0.35 0.00947 0.84 0.9285 0.9634 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N03 compound treatment 0.348 0.00471 0.39 0.352 0.0115 1.02 0.9952 0.9138 1411305 CBMicro_027141 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N04 compound treatment 0.356 0.0127 1.06 0.353 0.0125 1.11 1.5275 0.9997 1646193 CBMicro_027142 COc1ccc(CNC(=O)c2cccc(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N05 compound treatment 0.357 0.0137 1.14 0.354 0.0135 1.19 1.6488 0.9997 1939176 CBMicro_027143 COc1ccc(CNS(=O)(=O)c2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N06 compound treatment 0.357 0.0137 1.14 0.357 0.0165 1.46 1.8368 0.9924 1501867 CBMicro_027144 CC1CCN(CC1)C(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N07 compound treatment 0.359 0.0157 1.3 0.347 0.00647 0.57 1.3276 0.9319 1939177 CBMicro_027145 CCN(CC)CCCNC(=O)c1cc(ccc1Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N08 compound treatment 0.368 0.0247 2.05 0.362 0.0215 1.9 2.7959 0.9993 1298323 CBMicro_027146 CCOc1ccc(Nc2nc(cs2)c3ccccn3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N09 compound treatment 0.352 0.00871 0.72 0.334 -0.00653 -0.58 0.102 0.1101 1939178 CBMicro_027147 Cc1ccc(Cn2c(/N=C/c3ccccc3O)nc4ccccc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N10 compound treatment 0.36 0.0167 1.39 0.355 0.0145 1.28 1.8876 0.9992 1145474 CBMicro_027148 Nc1nc2CCCCCc2c(c1C#N)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N11 compound treatment 0.389 0.0457 3.79 0.365 0.0245 2.17 4.2166 0.9648 1939179 CBMicro_027149 CCCCCCOc1ccc(cc1)N2C(=O)CC(NCc3ccc(OC)cc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N12 compound treatment 0.392 0.0487 4.04 0.366 0.0255 2.26 4.4554 0.9621 1939180 CBMicro_027150 CC(C)c1ccc(cc1)c2nn(cc2/C=N/O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N13 compound treatment 0.371 0.0277 2.3 0.366 0.0255 2.26 3.2227 1.0 1939181 CBMicro_027151 Clc1ccc(cc1)c2ccc(/C=N/Nc3nncc(n3)c4ccccc4)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N14 compound treatment 0.382 0.0387 3.21 0.374 0.0335 2.97 4.3697 0.9992 1939182 CBMicro_027152 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(Br)cc3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N15 compound treatment 0.351 0.00771 0.64 0.341 4.69E-4 0.04 0.482 0.7514 1939183 CBMicro_027153 OC(=O)CCCCC(=O)NC1=NCCS1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N16 compound treatment 0.35 0.00671 0.56 0.353 0.0125 1.11 1.1752 0.9497 1939184 CBMicro_027154 Clc1ccc(cc1Cl)N2NC(=O)/C(=C\3/C(=O)Nc4ccccc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N17 compound treatment 0.364 0.0207 1.72 0.369 0.0285 2.52 2.9997 0.9825 1397338 CBMicro_027155 COc1ccc(OC)c(NC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N18 compound treatment 0.352 0.00871 0.72 0.349 0.00847 0.75 1.042 0.9998 1408574 CBMicro_027156 Cc1sc(NC(=O)c2ccc(C)cc2)nc1C3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N19 compound treatment 0.396 0.0527 4.38 0.37 0.0295 2.61 4.9409 0.9696 1448233 CBMicro_027157 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Cl)cc3)c(=O)n2C1c4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N20 compound treatment 0.35 0.00671 0.56 0.352 0.0115 1.02 1.1126 0.9599 1717329 CBMicro_027158 COc1ccc(C(=O)NCc2cccnc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N21 compound treatment 0.368 0.0247 2.05 0.366 0.0255 2.26 3.0465 0.9989 1939185 CBMicro_027159 COc1cc(ccc1c2ccc(/C=C(\C#N)/C(=O)N)o2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N22 compound treatment 0.366 0.0227 1.89 0.358 0.0175 1.55 2.4278 0.9952 1939186 CBMicro_027160 Ic1ccc(N/N=C/c2ccc(cc2)N3CCOCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N23 positive control 0.09 -0.253 -21.03 0.089 -0.252 -22.29 -30.6312 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 N24 positive control 0.093 -0.25 -20.78 0.094 -0.247 -21.85 -30.1418 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O01 mock treatment 0.344 7.1E-4 0.06 0.346 0.00547 0.48 0.3844 0.7873 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O02 mock treatment 0.348 0.00471 0.39 0.342 0.00147 0.13 0.3685 0.8943 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O03 compound treatment 0.35 0.00671 0.56 0.349 0.00847 0.75 0.9246 0.9892 1939187 CBMicro_027161 Cc1ccccc1C(=O)N/N=C/c2ccc(OCC(=O)N3CCCCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O04 compound treatment 0.351 0.00771 0.64 0.35 0.00947 0.84 1.0459 0.9911 1939188 CBMicro_027162 CCN/C(=N\CC)/SC1CC(=O)N(C1=O)c2cccc(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O05 compound treatment 0.349 0.00571 0.47 0.353 0.0125 1.11 1.1165 0.9286 1705025 CBMicro_027163 CC(C)NC(=O)c1ccccc1N(Cc2ccccc2)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O06 compound treatment 0.353 0.00971 0.81 0.354 0.0135 1.19 1.414 0.9817 1939189 CBMicro_027164 Clc1ccc(cc1Cl)N2NC(=O)/C(=C\c3cccs3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O07 compound treatment 0.353 0.00971 0.81 0.342 0.00147 0.13 0.662 0.8108 1362885 CBMicro_027165 Clc1ccc(cc1)C(=O)N(C2CS(=O)(=O)C=C2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O08 compound treatment 0.368 0.0247 2.05 0.367 0.0265 2.35 3.1092 0.9978 1535745 CBMicro_027166 Clc1ccc(cc1Cl)c2ccc(o2)C(=S)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O09 compound treatment 0.391 0.0477 3.96 0.387 0.0465 4.12 5.7127 0.9998 1939190 CBMicro_027167 CCc1nnc(NS(=O)(=O)c2ccc(N/C=C\3/C(=NN(C3=O)c4ccc(C)cc4)C)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O10 compound treatment 0.351 0.00771 0.64 0.346 0.00547 0.48 0.7953 0.9906 1939191 CBMicro_027168 CCOC(=O)c1c(NC(=O)c2ccco2)scc1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O11 compound treatment 0.664 0.321 26.62 0.669 0.328 29.11 39.4102 0.999 1939192 CBMicro_027169 CCN1CCN(CC1)c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O12 compound treatment 0.356 0.0127 1.06 0.351 0.0105 0.93 1.4021 0.9979 1939193 CBMicro_027170 Brc1cccc(c1)N2C(=O)CC(NCc3ccc4OCOc4c3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O13 compound treatment 0.353 0.00971 0.81 0.346 0.00547 0.48 0.9127 0.9704 1939194 CBMicro_027171 OC(=O)CC1S/C(=N/N=C/c2ccco2)/NC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O14 compound treatment 0.353 0.00971 0.81 0.349 0.00847 0.75 1.1007 0.9994 1322813 CBMicro_027172 C=CCc1cccc2cc(C(=O)N3CCN(Cc4ccccc4)CC3)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O15 compound treatment 0.35 0.00671 0.56 0.353 0.0125 1.11 1.1752 0.9497 1939195 CBMicro_027173 Cc1ccc(CN2CCN(CCNC(=O)C(=O)Nc3ccc(F)cc3)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O16 compound treatment 0.455 0.112 9.27 0.441 0.1 8.9 12.8536 0.9998 1939196 CBMicro_027174 Oc1cccc(/C=N/Nc2nncc(n2)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O17 compound treatment 0.358 0.0147 1.22 0.352 0.0115 1.02 1.5822 0.9958 1939197 CBMicro_027175 COc1ccccc1/C=C(/NC(=O)c2ccc(C)cc2)\C(=O)Nc3ccc(cc3)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O18 compound treatment 0.343 -2.9E-4 -0.02 0.347 0.00647 0.57 0.3883 0.6768 1939198 CBMicro_027176 COc1ccc(CCNC(=O)CC(=O)N/N=C/c2ccco2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O19 compound treatment 0.352 0.00871 0.72 0.35 0.00947 0.84 1.1046 0.9973 1939199 CBMicro_027177 NC(=O)/C(=C/c1ccc(o1)c2ccc(cc2Br)[N+](=O)[O-])/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O20 compound treatment 0.345 0.00171 0.14 0.349 0.00847 0.75 0.6311 0.8262 1442205 CBMicro_027178 Oc1c(CC(=O)NCc2ccncc2)c(=O)[nH]c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O21 compound treatment 0.35 0.00671 0.56 0.353 0.0125 1.11 1.1752 0.9497 1577031 CBMicro_027179 CCC(NS(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)NC(CC)C(=O)O)c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O22 compound treatment 0.352 0.00871 0.72 0.35 0.00947 0.84 1.1046 0.9973 1629511 CBMicro_027180 COc1ccc(cc1)C2SCCN2S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O23 positive control 0.087 -0.256 -21.28 0.09 -0.251 -22.2 -30.7447 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 O24 positive control 0.093 -0.25 -20.78 0.094 -0.247 -21.85 -30.1418 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P01 mock treatment 0.344 7.1E-4 0.06 0.339 -0.00153 -0.14 -0.0543 -0.367 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P02 mock treatment 0.351 0.00771 0.64 0.346 0.00547 0.48 0.7953 0.9906 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P03 compound treatment 0.355 0.0117 0.97 0.349 0.00847 0.75 1.2181 0.9918 1317419 CBMicro_027181 COc1ccc(C(=O)N2CCN(CC2)c3ccccc3)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P04 compound treatment 0.35 0.00671 0.56 0.348 0.00747 0.66 0.8619 0.9963 1939200 CBMicro_027182 COc1ccccc1NC(=O)/C(=C\c2cccnc2)/NC(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P05 compound treatment 0.339 -0.00429 -0.36 0.358 0.0175 1.55 0.8428 0.5306 1939201 CBMicro_027183 COc1ccc(OC)c(c1)N(CC(=O)NC(C)(C)CO)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P06 compound treatment 0.348 0.00471 0.39 0.351 0.0105 0.93 0.9325 0.9262 1695003 CBMicro_027184 COc1ccc(cc1)C(=O)Nc2nc(cs2)C3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P07 compound treatment 0.358 0.0147 1.22 0.355 0.0145 1.28 1.7702 0.9997 1939202 CBMicro_027185 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P08 compound treatment 0.348 0.00471 0.39 0.357 0.0165 1.46 1.3085 0.866 1244734 CBMicro_027186 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P09 compound treatment 0.355 0.0117 0.97 0.355 0.0145 1.28 1.5941 0.9907 1780047 CBMicro_027187 OC1C2CCC1C(CC2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P10 compound treatment 0.348 0.00471 0.39 0.356 0.0155 1.37 1.2458 0.8739 1623334 CBMicro_027188 CCCS(=O)(=O)c1c(C(=O)c2ccc(OC)cc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P11 compound treatment 0.344 7.1E-4 0.06 0.351 0.0105 0.93 0.6977 0.7505 1939203 CBMicro_027189 O=C(CN1CCOCC1)NCC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P12 compound treatment 0.349 0.00571 0.47 0.344 0.00347 0.31 0.5525 0.978 1313537 CBMicro_027190 OC(c1nc2ccccc2n1CC=C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P13 compound treatment 0.393 0.0497 4.13 0.396 0.0555 4.92 6.3941 0.9962 1263797 CBMicro_027191 N(c1nc(cs1)c2ccncc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P14 compound treatment 0.185 -0.158 -13.14 0.189 -0.152 -13.43 -18.7879 -0.9999 1657909 CBMicro_027192 OC(=O)C1Nc2ccc3ccccc3c2C4C=CCC41 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P15 compound treatment 0.349 0.00571 0.47 0.35 0.00947 0.84 0.9285 0.9634 1939204 CBMicro_027193 CC1(CC(=O)N/N=C/c2ccc(o2)c3ccc(Cl)cc3)OCCO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P16 compound treatment 0.382 0.0387 3.21 0.381 0.0405 3.59 4.8084 0.9985 1939205 CBMicro_027194 COc1ccccc1N2C(=O)C3ON(C(C3C2=O)c4cccc(Br)c4)c5ccccc5C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P17 compound treatment 0.352 0.00871 0.72 0.353 0.0125 1.11 1.2926 0.9789 1443034 CBMicro_027195 Cc1cc(nc2ccccc12)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P18 compound treatment 0.417 0.0737 6.12 0.343 0.00247 0.22 4.4817 0.7319 1939206 CBMicro_027196 CC(C)c1ccc(/C=C/C(=O)Nc2sc3CCCCc3c2C(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P19 compound treatment 0.354 0.0107 0.89 0.348 0.00747 0.66 1.0967 0.9894 1656128 CBMicro_027197 O=C(CSc1cccc2cccnc12)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P20 compound treatment 0.354 0.0107 0.89 0.349 0.00847 0.75 1.1594 0.9964 1939207 CBMicro_027198 COc1ccc(cc1c2ccc(/C=C(\C#N)/c3nc4cc(C)ccc4[nH]3)o2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P21 compound treatment 0.354 0.0107 0.89 0.356 0.0155 1.37 1.598 0.978 1939208 CBMicro_027199 CN1CCC(=NNC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)c3ccccc3)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P22 compound treatment 0.351 0.00771 0.64 0.351 0.0105 0.93 1.1086 0.9836 1781175 CBMicro_027200 Cc1cc(ccc1[N+](=O)[O-])C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P23 positive control 0.089 -0.254 -21.11 0.091 -0.25 -22.11 -30.5646 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.770 P24 positive control 0.095 -0.248 -20.61 0.096 -0.245 -21.67 -29.899 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A01 mock treatment 0.321 -0.0199 -1.65 0.328 -0.0152 -1.34 -2.118 -0.9947 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A02 mock treatment 0.332 -0.0089 -0.74 0.33 -0.0132 -1.17 -1.3469 -0.9758 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A03 compound treatment 0.332 -0.0089 -0.74 0.331 -0.0122 -1.08 -1.2842 -0.9831 1242357 CBMicro_027201 CCOC(=O)c1c(NC(=O)c2cccc(F)c2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A04 compound treatment 0.327 -0.0139 -1.15 0.33 -0.0132 -1.17 -1.6404 -1.0 1939209 CBMicro_027202 Oc1ccc(/C=N/NC(=O)NC2(CC3CC4CC(C3)C2)C4)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A05 compound treatment 0.332 -0.0089 -0.74 0.331 -0.0122 -1.08 -1.2842 -0.9831 1939210 CBMicro_027203 [O-][N+](=O)c1cc2OCOc2cc1/C=N/Nc3nc4nonc4nc3Nc5ccc(F)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A06 compound treatment 0.332 -0.0089 -0.74 0.333 -0.0102 -0.9 -1.1589 -0.9952 1780764 CBMicro_027204 Cc1cc(ccc1[N+](=O)[O-])C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A07 compound treatment 0.329 -0.0119 -0.99 0.339 -0.00416 -0.37 -0.959 -0.9096 1939211 CBMicro_027205 CCOC(=O)C1=NN(C(=O)c2cccc(Br)c2)C(O)(C1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A08 compound treatment 0.325 -0.0159 -1.32 0.331 -0.0122 -1.08 -1.6952 -0.9949 1573665 CBMicro_027206 C(Nc1ccc2ccccc2n1)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A09 compound treatment 0.343 0.0021 0.17 0.34 -0.00316 -0.28 -0.0745 -0.2261 1939212 CBMicro_027207 C/C(=N\O)/CCc1oc2ccc(Cl)cc2c1c3ccc(C)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A10 compound treatment 0.329 -0.0119 -0.99 0.329 -0.0142 -1.25 -1.5857 -0.993 1779831 CBMicro_027208 COc1ccc(cc1c2ccc(C=c3sc4nc5cc(C)c(C)cc5n4c3=O)o2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A11 compound treatment 0.45 0.109 9.06 0.46 0.117 10.35 13.7266 0.9978 1939213 CBMicro_027209 Oc1ccc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A12 compound treatment 0.335 -0.0059 -0.49 0.335 -0.00816 -0.72 -0.8575 -0.982 1406938 CBMicro_027210 COc1cc(OC)cc(c1)C(=O)NCC2CCCO2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A13 compound treatment 0.338 -0.0029 -0.24 0.333 -0.0102 -0.9 -0.8067 -0.8658 1397294 CBMicro_027211 CCOC(=O)COc1ccc(C=c2sc3nc4ccccc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A14 compound treatment 0.336 -0.0049 -0.41 0.323 -0.0202 -1.79 -1.5507 -0.8465 1939214 CBMicro_027212 COc1ccc(cc1)N2C(=O)CC(N3CCSCC3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A15 compound treatment 0.349 0.0081 0.67 0.344 8.44E-4 0.07 0.5284 0.7809 1939215 CBMicro_027213 COc1ccc(cc1NC(=O)c2ccc(cc2)N(C)C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A16 compound treatment 0.333 -0.0079 -0.66 0.331 -0.0122 -1.08 -1.2255 -0.9717 1718569 CBMicro_027214 CCOc1ccc(NS(=O)(=O)c2ccc3nsnc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A17 compound treatment 0.39 0.0491 4.08 0.384 0.0408 3.62 5.4418 0.9982 1939216 CBMicro_027215 CC1(C)CC(=O)C/C(=N/NC(=O)c2cc3ccccc3cc2O)/C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A18 compound treatment 0.35 0.0091 0.76 0.349 0.00584 0.52 0.9004 0.983 1939217 CBMicro_027216 FC(F)(F)c1cccc(N/N=C\2/C(=O)Nc3ccccc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A19 compound treatment 0.342 0.0011 0.09 0.341 -0.00216 -0.19 -0.0705 -0.3331 1939218 CBMicro_027217 Clc1ccc(cc1Cl)N2NC(=O)/C(=C\c3cccc(Br)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A20 compound treatment 0.334 -0.0069 -0.57 0.334 -0.00916 -0.81 -0.9788 -0.9855 1939219 CBMicro_027218 Oc1cccc(/C=C\2/NC(=S)NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A21 compound treatment 0.323 -0.0179 -1.49 0.322 -0.0212 -1.87 -2.3765 -0.9934 1939220 CBMicro_027219 Fc1ccccc1C(=O)Nc2ccc(cc2)C(=O)/C=C/c3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A22 compound treatment 0.329 -0.0119 -0.99 0.326 -0.0172 -1.52 -1.7737 -0.9782 1148298 CBMicro_027220 CCOc1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A23 positive control 0.083 -0.258 -21.41 0.085 -0.258 -22.88 -31.317 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 A24 positive control 0.085 -0.256 -21.24 0.087 -0.256 -22.7 -31.0742 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B01 mock treatment 0.329 -0.0119 -0.99 0.333 -0.0102 -0.9 -1.335 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B02 mock treatment 0.345 0.0041 0.34 0.339 -0.00416 -0.37 -0.0198 -0.0394 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B03 compound treatment 0.343 0.0021 0.17 0.342 -0.00116 -0.1 0.0508 0.2513 1939221 CBMicro_027221 CCOC(=O)c1[nH]c(C)c(C(=O)N/N=C/c2ccc(o2)c3ccc(Cl)cc3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B04 compound treatment 0.346 0.0051 0.42 0.347 0.00384 0.34 0.5403 0.9942 1588044 CBMicro_027222 COc1ccccc1CNC(=O)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B05 compound treatment 0.295 -0.0459 -3.81 0.288 -0.0552 -4.89 -6.1509 -0.9924 1939222 CBMicro_027223 OC(=O)C1Nc2c(cccc2C3C=CCC31)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B06 compound treatment 0.322 -0.0189 -1.57 0.338 -0.00516 -0.46 -1.4326 -0.8766 1730467 CBMicro_027224 Cc1ccc(c2csc(Nc3ccc(O)cc3)n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B07 compound treatment 0.345 0.0041 0.34 0.339 -0.00416 -0.37 -0.0198 -0.0394 1521733 CBMicro_027225 O=C1CN(CC(=O)N1)S(=O)(=O)c2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B08 compound treatment 0.346 0.0051 0.42 0.347 0.00384 0.34 0.5403 0.9942 1939223 CBMicro_027226 CCc1ccc(cc1)c2csc(n2)N3N=C(CC3c4ccc(F)cc4)c5cccs5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B09 compound treatment 0.347 0.0061 0.51 0.344 8.44E-4 0.07 0.411 0.8028 1939224 CBMicro_027227 COc1ccccc1OCC(=O)N/N=C/c2ccccc2Sc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B10 compound treatment 0.344 0.0031 0.26 0.342 -0.00116 -0.1 0.1095 0.3954 1615227 CBMicro_027228 Fc1ccc(cc1)C(=O)Nc2nnc(s2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B11 compound treatment 0.352 0.0111 0.92 0.346 0.00284 0.25 0.8298 0.8686 1385197 CBMicro_027229 Clc1cccc(c1)C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B12 compound treatment 0.381 0.0401 3.33 0.39 0.0468 4.15 5.2895 0.994 1939225 CBMicro_027230 COc1ccc(cc1)N(CC(=O)N/N=C\c2ccccc2O)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B13 compound treatment 0.351 0.0101 0.84 0.358 0.0148 1.32 1.5231 0.9763 1520218 CBMicro_027231 O=C(NCc1ccco1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B14 compound treatment 0.342 0.0011 0.09 0.348 0.00484 0.43 0.3681 0.8388 1939226 CBMicro_027232 Cc1cc(nn1CC(=O)Nc2ccc(OC(F)(F)F)cc2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B15 compound treatment 0.351 0.0101 0.84 0.345 0.00184 0.16 0.7084 0.8293 1939227 CBMicro_027233 [O-][N+](=O)c1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccco4)cc(Oc5cccnc5)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B16 compound treatment 0.344 0.0031 0.26 0.339 -0.00416 -0.37 -0.0785 -0.1746 1393579 CBMicro_027234 Fc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B17 compound treatment 0.344 0.0031 0.26 0.347 0.00384 0.34 0.4228 0.9904 1939228 CBMicro_027235 CC1CCCCN1C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B18 compound treatment 0.488 0.147 12.21 0.474 0.131 11.6 16.8346 0.9997 1939229 CBMicro_027236 Cc1ccc(C)c(/N=C\2/NC(=O)/C(=C/c3ccc(cc3)N4CCOCC4)/S2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B19 compound treatment 0.341 1.0E-4 0.01 0.337 -0.00616 -0.55 -0.3799 -0.6963 1939230 CBMicro_027237 Fc1ccc(/C=C/C(=O)c2nc3ccccc3s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B20 compound treatment 0.345 0.0041 0.34 0.34 -0.00316 -0.28 0.0429 0.0974 1939231 CBMicro_027238 O=C(CSc1nnnn1c2ccccc2)CSc3nnnn3c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B21 compound treatment 0.345 0.0041 0.34 0.342 -0.00116 -0.1 0.1682 0.4733 1516290 CBMicro_027239 CC(C)c1ccc(cc1)c2nn(cc2c3nnc(N)o3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B22 compound treatment 0.34 -9.0E-4 -0.07 0.341 -0.00216 -0.19 -0.188 -0.9161 1939232 CBMicro_027240 COc1ccc(cc1)C(O)(C(=O)NCCCCOc2ccccc2)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B23 positive control 0.081 -0.26 -21.58 0.085 -0.258 -22.88 -31.4344 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 B24 positive control 0.084 -0.257 -21.33 0.087 -0.256 -22.7 -31.1329 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C01 mock treatment 0.347 0.0061 0.51 0.343 -1.56E-4 -0.01 0.3483 0.6875 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C02 mock treatment 0.354 0.0131 1.09 0.353 0.00984 0.87 1.3859 0.994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C03 compound treatment 0.312 -0.0289 -2.4 0.347 0.00384 0.34 -1.4557 -0.6007 1540825 CBMicro_027241 COc1ccc(NC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C04 compound treatment 0.351 0.0101 0.84 0.359 0.0158 1.4 1.5858 0.9696 1939233 CBMicro_027242 Clc1cccc(/C=C/C(=O)c2ccc3OCCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C05 compound treatment 0.238 -0.103 -8.54 0.195 -0.148 -13.13 -15.3248 -0.9783 1248538 CBMicro_027243 Cc1c(Cl)ccc2C3C=CCC3C(Nc12)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C06 compound treatment 0.312 -0.0289 -2.4 0.342 -0.00116 -0.1 -1.769 -0.7366 1658023 CBMicro_027244 Cc1ccc(N2C(=O)c3ccc(cc3C2=O)C(=O)O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C07 compound treatment 0.357 0.0161 1.34 0.349 0.00584 0.52 1.3113 0.9148 1939234 CBMicro_027245 [O-][N+](=O)c1ccc(Br)c(c1)c2ccc(/C=C/3\NC(=S)NC3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C08 compound treatment 0.349 0.0081 0.67 0.352 0.00884 0.78 1.0297 0.9971 1159952 CBMicro_027246 Cc1sc(NC(=O)Nc2ccccc2)nc1C3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C09 compound treatment 0.35 0.0091 0.76 0.345 0.00184 0.16 0.6497 0.8406 1939235 CBMicro_027247 COc1ccc(Cl)cc1N(CC(=O)Nc2cc(C)ccc2C)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C10 compound treatment 0.413 0.0721 5.99 0.404 0.0608 5.39 8.0453 0.9986 1939236 CBMicro_027248 CC(C)OC(=O)/C(=C\c1ccc(C)o1)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C11 compound treatment 0.344 0.0031 0.26 0.346 0.00284 0.25 0.3602 0.9999 1685299 CBMicro_027249 COc1cc(OC)cc(c1)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C12 compound treatment 0.339 -0.0019 -0.16 0.345 0.00184 0.16 0.004 0.0176 1939237 CBMicro_027250 CCOC(=O)c1c(NC(=O)c2cc(ccc2Cl)[N+](=O)[O-])sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C13 compound treatment 0.426 0.0851 7.06 0.438 0.0948 8.41 10.939 0.9963 1130529 CBMicro_027251 COc1cc(ccc1OCC#N)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C14 compound treatment 0.343 0.0021 0.17 0.34 -0.00316 -0.28 -0.0745 -0.2261 1575834 CBMicro_027252 CC(CC(=O)c1cccs1)CC(=O)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C15 compound treatment 0.344 0.0031 0.26 0.344 8.44E-4 0.07 0.2349 0.8763 1294186 CBMicro_027253 Cc1nc2ccccn2c1C(=O)NC3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C16 compound treatment 0.344 0.0031 0.26 0.352 0.00884 0.78 0.7362 0.8924 1939238 CBMicro_027254 COc1ccc(cc1)N(CC(=O)NCC=C)S(=O)(=O)c2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C17 compound treatment 0.343 0.0021 0.17 0.346 0.00284 0.25 0.3015 0.9838 1297440 CBMicro_027255 Cc1ccc2c(nc3sc(=Cc4cccc(Cl)c4Cl)c(=O)n32)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C18 compound treatment 0.344 0.0031 0.26 0.349 0.00584 0.52 0.5482 0.9479 1529760 CBMicro_027256 CC(O)c1nc2ccccc2n1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C19 compound treatment 0.352 0.0111 0.92 0.355 0.0118 1.05 1.3938 0.9979 1523075 CBMicro_027257 COc1ccc(CNC(=O)c2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C20 compound treatment 0.372 0.0311 2.58 0.393 0.0498 4.42 4.9491 0.9673 1048497 CBMicro_027258 N1C(Nc2cccc3cccc1c23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C21 compound treatment 0.347 0.0061 0.51 0.343 -1.56E-4 -0.01 0.3483 0.6875 1939239 CBMicro_027259 Brc1ccc(OCc2ccccc2)c(/C=C(\C#N)/c3nc4ccccc4[nH]3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C22 compound treatment 0.344 0.0031 0.26 0.34 -0.00316 -0.28 -0.0158 -0.0416 1578978 CBMicro_027260 CCN(CC)CCn1c(SCc2ccccc2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C23 positive control 0.081 -0.26 -21.58 0.084 -0.259 -22.97 -31.497 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 C24 positive control 0.085 -0.256 -21.24 0.089 -0.254 -22.52 -30.9489 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D01 mock treatment 0.343 0.0021 0.17 0.346 0.00284 0.25 0.3015 0.9838 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D02 mock treatment 0.346 0.0051 0.42 0.346 0.00284 0.25 0.4776 0.9693 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D03 compound treatment 0.347 0.0061 0.51 0.347 0.00384 0.34 0.599 0.9814 1939240 CBMicro_027261 Cc1ccc(o1)c2ccccc2N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D04 compound treatment 0.341 1.0E-4 0.01 0.345 0.00184 0.16 0.1214 0.7421 1939241 CBMicro_027262 Cc1c([N+](=O)[O-])c(nn1CC(=O)Nc2sc3CCCCc3c2C#N)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D05 compound treatment 0.367 0.0261 2.17 0.351 0.00784 0.7 2.0237 0.8893 1939242 CBMicro_027263 CCCCSc1nc(=O)c(n[nH]1)c2ccccc2N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D06 compound treatment 0.347 0.0061 0.51 0.343 -1.56E-4 -0.01 0.3483 0.6875 1939243 CBMicro_027264 Fc1ccc(NC=C2C(=O)CC(CC2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D07 compound treatment 0.353 0.0121 1.0 0.341 -0.00216 -0.19 0.5752 0.5625 1734898 CBMicro_027265 Oc1ccc(cc1)N2C(=O)c3cc4ccccc4cc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D08 compound treatment 0.373 0.0321 2.66 0.37 0.0268 2.38 3.5665 0.9984 1939244 CBMicro_027266 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C\c3cccnc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D09 compound treatment 0.413 0.0721 5.99 0.389 0.0458 4.06 7.1053 0.9822 1692742 CBMicro_027267 CCc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D10 compound treatment 0.332 -0.0089 -0.74 0.348 0.00484 0.43 -0.2189 -0.2562 1324903 CBMicro_027268 CCc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D11 compound treatment 0.348 0.0071 0.59 0.35 0.00684 0.61 0.8457 0.9999 1492925 CBMicro_027269 COC(=O)CN(Cc1ccccc1)S(=O)(=O)c2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D12 compound treatment 0.343 0.0021 0.17 0.342 -0.00116 -0.1 0.0508 0.2513 1325785 CBMicro_027270 CN(C)CCCN1C(SCC1=O)c2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D13 compound treatment 0.349 0.0081 0.67 0.354 0.0108 0.96 1.155 0.9848 1939245 CBMicro_027271 Cc1nc(NNC(=O)c2ccc(Cl)cc2)cc(n1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D14 compound treatment 0.344 0.0031 0.26 0.338 -0.00516 -0.46 -0.1411 -0.2691 1329153 CBMicro_027272 Cc1cc(C)nc(SCCN2CCCCC2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D15 compound treatment 0.359 0.0181 1.5 0.355 0.0118 1.05 1.8047 0.9846 1939246 CBMicro_027273 COc1ccc(OC)c(/C=C\2/C=C(OC2=O)c3cccc4ccccc34)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D16 compound treatment 0.376 0.0351 2.91 0.372 0.0288 2.56 3.868 0.9979 1628833 CBMicro_027274 Cc1cc(Nc2ccccc2)nn1C(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D17 compound treatment 0.351 0.0101 0.84 0.343 -1.56E-4 -0.01 0.5831 0.6953 1316313 CBMicro_027275 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1OCc5ccc(C)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D18 compound treatment 0.344 0.0031 0.26 0.34 -0.00316 -0.28 -0.0158 -0.0416 1939247 CBMicro_027276 Cc1cccc(Oc2cc(NC(=O)c3cccc(F)c3)cc(c2)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D19 compound treatment 0.355 0.0141 1.17 0.353 0.00984 0.87 1.4446 0.9895 1939248 CBMicro_027277 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccc(OC)cc3)c4ccc(OC)cc24)S1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D20 compound treatment 0.356 0.0151 1.25 0.356 0.0128 1.14 1.6913 0.9988 1939249 CBMicro_027278 CCOC(=O)/C(=C/1\NC(C)(C)Cc2ccccc12)/C(=O)Nc3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D21 compound treatment 0.349 0.0081 0.67 0.34 -0.00316 -0.28 0.2777 0.3813 1939250 CBMicro_027279 COc1ccc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D22 compound treatment 0.345 0.0041 0.34 0.347 0.00384 0.34 0.4816 1.0 1156231 CBMicro_027280 COc1ccc(cc1)c2c(Cc3ccccc3)nn4c(=O)c5CCCc5[nH]c24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D23 positive control 0.082 -0.259 -21.49 0.087 -0.256 -22.7 -31.2503 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 D24 positive control 0.087 -0.254 -21.08 0.091 -0.252 -22.35 -30.7062 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E01 mock treatment 0.336 -0.0049 -0.41 0.336 -0.00716 -0.63 -0.7361 -0.977 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E02 mock treatment 0.347 0.0061 0.51 0.344 8.44E-4 0.07 0.411 0.8028 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E03 compound treatment 0.349 0.0081 0.67 0.348 0.00484 0.43 0.779 0.9765 1516056 CBMicro_027281 O=C1c2ccccc2-c3ccc(cc13)S(=O)(=O)N4CC(=O)NC(=O)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E04 compound treatment 0.346 0.0051 0.42 0.348 0.00484 0.43 0.6029 1.0 1639103 CBMicro_027282 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E05 compound treatment 0.342 0.0011 0.09 0.34 -0.00316 -0.28 -0.1332 -0.4527 1939251 CBMicro_027283 O=C(CC(=O)NC1CCCCC1)N/N=C/c2ccccc2OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E06 compound treatment 0.335 -0.0059 -0.49 0.344 8.44E-4 0.07 -0.2935 -0.5923 1939252 CBMicro_027284 O=C1CN=C(Nc2nc3ccccc3o2)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E07 compound treatment 0.31 -0.0309 -2.57 0.344 8.44E-4 0.07 -1.7611 -0.6862 1939253 CBMicro_027285 Oc1ccc(/C=N/Nc2nncc(n2)c3ccccc3)c(O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E08 compound treatment 0.35 0.0091 0.76 0.348 0.00484 0.43 0.8377 0.9641 1939254 CBMicro_027286 Nc1nonc1C(=O)N/N=C/c2c[nH]nc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E09 compound treatment 0.346 0.0051 0.42 0.345 0.00184 0.16 0.4149 0.9143 1492954 CBMicro_027287 COc1ccc(OC)c(c1)S(=O)(=O)n2nnc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E10 compound treatment 0.347 0.0061 0.51 0.346 0.00284 0.25 0.5363 0.9481 1665118 CBMicro_027288 O=C(CCN1C(=O)c2ccccc2C1=O)NCc3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E11 compound treatment 0.352 0.0111 0.92 0.342 -0.00116 -0.1 0.5791 0.6246 1320395 CBMicro_027289 Ic1ccccc1C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E12 compound treatment 0.338 -0.0029 -0.24 0.347 0.00384 0.34 0.0706 0.1693 1274251 CBMicro_027290 O=C(CN(c1ccccc1)S(=O)(=O)c2ccccc2)NCc3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E13 compound treatment 0.895 0.554 46.0 0.902 0.559 49.53 67.5475 0.9993 1939255 CBMicro_027291 CCOC(=O)/C(=C\c1cccn1C)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E14 compound treatment 0.344 0.0031 0.26 0.34 -0.00316 -0.28 -0.0158 -0.0416 1518114 CBMicro_027292 COc1ccc(OC)c(c1)S(=O)(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E15 compound treatment 0.385 0.0441 3.66 0.395 0.0518 4.59 5.8376 0.9937 1939256 CBMicro_027293 C/C(=N/NC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c2ccccc2)/c3ccccc3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E16 compound treatment 0.43 0.0891 7.4 0.427 0.0838 7.43 10.4845 1.0 1612201 CBMicro_027294 Cc1cc(c2ccccc2)c3ccc(O)cc3n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E17 compound treatment 0.352 0.0111 0.92 0.343 -1.56E-4 -0.01 0.6418 0.6964 1939257 CBMicro_027295 CC(=O)CCc1oc2ccc(C)cc2c1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E18 compound treatment 0.613 0.272 22.59 0.529 0.186 16.47 27.6191 0.9879 1939258 CBMicro_027296 CCN(CC)c1ccc(/C=N/NC(=O)c2nonc2N)c(OCc3ccc(Cl)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E19 compound treatment 0.315 -0.0259 -2.15 0.34 -0.00316 -0.28 -1.7182 -0.7924 1939259 CBMicro_027297 Cc1ccc(SC2CC(=O)N(C2=O)c3ccccc3C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E20 compound treatment 0.345 0.0041 0.34 0.34 -0.00316 -0.28 0.0429 0.0974 1939260 CBMicro_027298 O=C1N(CCN2CCN(CC2)S(=O)(=O)c3cccc4cccnc34)C(=O)c5cccc6cccc1c56 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E21 compound treatment 0.365 0.0241 2.0 0.364 0.0208 1.85 2.7209 0.9992 1939261 CBMicro_027299 Cc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(F)cc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E22 compound treatment 0.339 -0.0019 -0.16 0.345 0.00184 0.16 0.004 0.0176 1939262 CBMicro_027300 NC(=O)C1CCN(CC1)C2CC(=O)N(C2=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E23 positive control 0.082 -0.259 -21.49 0.089 -0.254 -22.52 -31.125 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 E24 positive control 0.088 -0.253 -21.0 0.093 -0.25 -22.17 -30.5221 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F01 mock treatment 0.338 -0.0029 -0.24 0.339 -0.00416 -0.37 -0.4307 -0.9788 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F02 mock treatment 0.339 -0.0019 -0.16 0.344 8.44E-4 0.07 -0.0587 -0.3361 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F03 compound treatment 0.367 0.0261 2.17 0.364 0.0208 1.85 2.8383 0.9968 1939263 CBMicro_027301 Cc1ccc(o1)C(c2ccc(C)o2)c3cc(Br)cc([N+](=O)[O-])c3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F04 compound treatment 0.346 0.0051 0.42 0.337 -0.00616 -0.55 -0.0864 -0.1251 1939264 CBMicro_027302 CNC(=S)N(C)/N=C/C(=N\N(C)C(=S)NC)/C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F05 compound treatment 0.352 0.0111 0.92 0.365 0.0218 1.94 2.0204 0.9424 1128719 CBMicro_027303 COc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)OCc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F06 compound treatment 0.343 0.0021 0.17 0.348 0.00484 0.43 0.4268 0.9212 1226551 CBMicro_027304 Fc1ccc(COc2cc3oc(=O)c4CCCc4c3cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F07 compound treatment 0.338 -0.0029 -0.24 0.345 0.00184 0.16 -0.0547 -0.188 1157179 CBMicro_027305 Oc1cccc(Nc2nc(cs2)c3ccccn3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F08 compound treatment 0.363 0.0221 1.83 0.383 0.0398 3.53 3.7942 0.9535 1551062 CBMicro_027306 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3n(cnc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F09 compound treatment 0.359 0.0181 1.5 0.336 -0.00716 -0.63 0.6141 0.3765 1728640 CBMicro_027307 CN(C)C(=S)NC(=O)C1(CC2CC3(C)CC(C)(C2)C1)C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F10 compound treatment 0.341 1.0E-4 0.01 0.353 0.00984 0.87 0.6227 0.7138 1939265 CBMicro_027308 COc1ccc(cc1)N(CC(=O)NC(C)c2ccccc2)S(=O)(=O)c3ccc(OC)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F11 compound treatment 0.363 0.0221 1.83 0.358 0.0148 1.32 2.2275 0.9867 1939266 CBMicro_027309 COc1ccccc1/N=C/c2c(O)c(Br)cc3oc4CCCCc4c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F12 compound treatment 0.355 0.0141 1.17 0.342 -0.00116 -0.1 0.7553 0.6428 1939267 CBMicro_027310 Cc1cc(C)c2nc3sc(=Cc4ccc(o4)c5cc(C)c(C)cc5[N+](=O)[O-])c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F13 compound treatment 0.347 0.0061 0.51 0.358 0.0148 1.32 1.2883 0.9139 1939268 CBMicro_027311 CC(C)C1=NN(C(=O)c2ccccc2)C(O)(C1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F14 compound treatment 0.356 0.0151 1.25 0.359 0.0158 1.4 1.8793 0.9984 1238468 CBMicro_027312 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC)c(OC)c3)c(=O)n2C1c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F15 compound treatment 0.356 0.0151 1.25 0.345 0.00184 0.16 1.002 0.7926 1939269 CBMicro_027313 Cc1c(Br)c(nn1CC(=O)Nc2c(F)cc(F)cc2Br)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F16 compound treatment 0.363 0.0221 1.83 0.363 0.0198 1.76 2.5409 0.9998 1939270 CBMicro_027314 Cc1cc([N+](=O)[O-])c(C)c(c1)c2ccc(C=c3sc4nc5c(C)cc(C)cc5n4c3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F17 compound treatment 0.401 0.0601 4.99 0.406 0.0628 5.57 7.4662 0.9985 1939271 CBMicro_027315 COCc1cc(C)nc(N/N=C/c2c[nH]c3ccccc23)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F18 compound treatment 0.205 -0.136 -11.28 0.238 -0.105 -9.32 -14.5674 -0.9955 1454114 CBMicro_027316 CC1(OC2(C)C=C1)C3C2C(=O)N(C3=O)c4ccc(F)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F19 compound treatment 0.372 0.0311 2.58 0.383 0.0398 3.53 4.3225 0.9882 1939272 CBMicro_027317 FC(F)(F)c1cc(nc2nc(nn12)C(=O)NCc3cccs3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F20 compound treatment 0.367 0.0261 2.17 0.365 0.0218 1.94 2.901 0.9984 1939273 CBMicro_027318 COc1ccc(OC)c(c1)C2=C/C(=C/c3cc(OC)c(OC)c(OC)c3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F21 compound treatment 0.362 0.0211 1.75 0.356 0.0128 1.14 2.0435 0.9782 1588596 CBMicro_027319 CCc1ccccc1NC(=O)CC2Sc3ccccc3NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F22 compound treatment 0.35 0.0091 0.76 0.34 -0.00316 -0.28 0.3364 0.4176 1241267 CBMicro_027320 COc1ccc(cc1)N(CC(=O)NCC2CCCO2)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F23 positive control 0.085 -0.256 -21.24 0.087 -0.256 -22.7 -31.0742 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 F24 positive control 0.088 -0.253 -21.0 0.096 -0.247 -21.9 -30.3341 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G01 mock treatment 0.328 -0.0129 -1.07 0.337 -0.00616 -0.55 -1.1431 -0.951 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G02 mock treatment 0.337 -0.0039 -0.32 0.339 -0.00416 -0.37 -0.4894 -0.9979 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G03 compound treatment 0.341 1.0E-4 0.01 0.335 -0.00816 -0.72 -0.5052 -0.6989 1218893 CBMicro_027321 COc1ccc(NC(C)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G04 compound treatment 0.345 0.0041 0.34 0.345 0.00184 0.16 0.3562 0.9435 1939274 CBMicro_027322 CCC1=NN(C(=O)c2ccccc2Cl)C(O)(C1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G05 compound treatment 0.342 0.0011 0.09 0.34 -0.00316 -0.28 -0.1332 -0.4527 1939275 CBMicro_027323 Fc1ccccc1N2CCN(CC2)C3CC(=O)N(C3=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G06 compound treatment 0.347 0.0061 0.51 0.345 0.00184 0.16 0.4736 0.8901 1701019 CBMicro_027324 CC(C)(C)c1ccc(CSc2nc3ccccc3c(=O)[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G07 compound treatment 0.396 0.0551 4.57 0.4 0.0568 5.04 6.7967 0.9988 1939276 CBMicro_027325 COc1ccc(NC(=O)/C(=C\c2ccc(Br)cc2)/NC(=O)c3ccccc3F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G08 compound treatment 0.359 0.0181 1.5 0.365 0.0218 1.94 2.4314 0.9922 1939277 CBMicro_027326 O=C1/C(=C/c2c3ccccc3nc4ccccc24)/Sc5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G09 compound treatment 0.346 0.0051 0.42 0.343 -1.56E-4 -0.01 0.2896 0.6836 1432137 CBMicro_027327 COc1cc(F)ccc1S(=O)(=O)N2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G10 compound treatment 0.336 -0.0049 -0.41 0.347 0.00384 0.34 -0.0468 -0.0882 1939278 CBMicro_027328 CCOC(=O)C1=C(N)OC(=C(C1c2cccnc2)C(=O)OC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G11 compound treatment 0.335 -0.0059 -0.49 0.348 0.00484 0.43 -0.0428 -0.0657 1322823 CBMicro_027329 COc1ccc(cc1)C(=O)Cn2cnc3c(C#N)c4CCCCCn4c3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G12 compound treatment 0.354 0.0131 1.09 0.358 0.0148 1.32 1.6992 0.9955 1322151 CBMicro_027330 CCOc1ccc(cc1)C(=O)Nc2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G13 compound treatment 0.488 0.147 12.21 0.506 0.163 14.43 18.8399 0.9965 1939279 CBMicro_027331 CCOc1cc(/C=C(\C#N)/c2nc3cc(C)ccc3[nH]2)cc(I)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G14 compound treatment 0.361 0.0201 1.67 0.367 0.0238 2.11 2.6741 0.9932 1338871 CBMicro_027332 COc1ccc(CNC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G15 compound treatment 0.377 0.0361 3.0 0.383 0.0398 3.53 4.616 0.9967 1939280 CBMicro_027333 CC(=O)CCc1oc2ccc(C)cc2c1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G16 compound treatment 0.375 0.0341 2.83 0.381 0.0378 3.35 4.3733 0.9964 1258109 CBMicro_027334 Clc1ccc(cc1Cl)c2csc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G17 compound treatment 0.382 0.0411 3.41 0.384 0.0408 3.62 4.9722 0.9996 1939281 CBMicro_027335 N(c1nc(cs1)c2cccs2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G18 compound treatment 0.343 0.0021 0.17 0.358 0.0148 1.32 1.0535 0.7939 1342248 CBMicro_027336 COc1ccc2n(C)c(SCC(O)c3ccccc3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G19 compound treatment 0.397 0.0561 4.66 0.406 0.0628 5.57 7.2314 0.996 1597036 CBMicro_027337 COc1cc(C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5)c(Br)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G20 compound treatment 0.38 0.0391 3.25 0.389 0.0458 4.06 5.1681 0.9938 1939282 CBMicro_027338 COc1ccc(OC)c(c1)C2=C/C(=C/c3ccc4OCOc4c3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G21 compound treatment 0.339 -0.0019 -0.16 0.347 0.00384 0.34 0.1293 0.3445 1418399 CBMicro_027339 COc1cc(cc(OC)c1OC)c2nnc(S)n2CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G22 compound treatment 0.35 0.0091 0.76 0.346 0.00284 0.25 0.7124 0.8945 1939283 CBMicro_027340 CCn1c(/N=C/c2cccc(CC=C)c2O)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G23 positive control 0.085 -0.256 -21.24 0.088 -0.255 -22.61 -31.0116 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 G24 positive control 0.092 -0.249 -20.66 0.096 -0.247 -21.9 -30.0993 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H01 mock treatment 0.333 -0.0079 -0.66 0.34 -0.00316 -0.28 -0.6615 -0.9278 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H02 mock treatment 0.337 -0.0039 -0.32 0.347 0.00384 0.34 0.0119 0.0254 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H03 compound treatment 0.336 -0.0049 -0.41 0.345 0.00184 0.16 -0.1721 -0.3926 1939284 CBMicro_027341 Clc1ccc(NC(=O)Nc2ccc(cc2)c3nc4ccccc4s3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H04 compound treatment 0.344 0.0031 0.26 0.345 0.00184 0.16 0.2975 0.976 1939285 CBMicro_027342 COc1ccc(/C=C\2/C=C(OC2=O)c3ccc(OC)cc3OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H05 compound treatment 0.378 0.0371 3.08 0.38 0.0368 3.27 4.4867 0.9996 1517656 CBMicro_027343 O=C(Nc1nc2ccccc2s1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H06 compound treatment 0.349 0.0081 0.67 0.352 0.00884 0.78 1.0297 0.9971 1939286 CBMicro_027344 CCCCSc1nnc-2c(OC(Nc3ccccc32)/C=C/c4ccccc4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H07 compound treatment 0.341 1.0E-4 0.01 0.325 -0.0182 -1.61 -1.1319 -0.7034 1939287 CBMicro_027345 CC(C)/C=C/1\CCCC\C1=N/NC(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H08 compound treatment 0.358 0.0171 1.42 0.353 0.00984 0.87 1.6207 0.9727 1939288 CBMicro_027346 [O-][N+](=O)c1cc(ccc1Oc2cccc(C=c3sc4nc5ccccc5n4c3=O)c2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H09 compound treatment 0.33 -0.0109 -0.9 0.345 0.00184 0.16 -0.5243 -0.5702 1939289 CBMicro_027347 COc1ccc(CCNC(=O)CC(=O)N/N=C/c2ccc(cc2)C(C)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H10 compound treatment 0.338 -0.0029 -0.24 0.36 0.0168 1.49 0.8853 0.5855 1939290 CBMicro_027348 Cc1c(cnn1c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H11 compound treatment 0.343 0.0021 0.17 0.361 0.0178 1.58 1.2415 0.7803 1939291 CBMicro_027349 Clc1ccc(cc1)C(CC(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H12 compound treatment 0.507 0.166 13.79 0.478 0.135 11.95 18.2006 0.9975 1939292 CBMicro_027350 Cc1ccc(cc1Cl)c2ccc(/C=N/n3nnnc3N)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H13 compound treatment 0.342 0.0011 0.09 0.347 0.00384 0.34 0.3054 0.8661 1939293 CBMicro_027351 Cc1cc(cc(C)c1NC(=O)CN2CCCCC2)C3(CCCCC3)c4cc(C)c(NC(=O)CN5CCCCC5)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H14 compound treatment 0.337 -0.0039 -0.32 0.34 -0.00316 -0.28 -0.4267 -0.9973 1939294 CBMicro_027352 [O-][N+](=O)c1ccc(CSc2n[nH]c(=O)[nH]c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H15 compound treatment 0.408 0.0671 5.57 0.417 0.0738 6.54 8.5664 0.9968 1480973 CBMicro_027353 Cc1cc(NC(=O)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H16 compound treatment 0.335 -0.0059 -0.49 0.343 -1.56E-4 -0.01 -0.3561 -0.7268 1939295 CBMicro_027354 Cc1nn(CC(=O)Nc2ccccc2C(F)(F)F)c(C)c1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H17 compound treatment 0.789 0.448 37.2 0.777 0.434 38.45 53.4918 0.9999 1939296 CBMicro_027355 CC1CN(CCN1)c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H18 compound treatment 0.356 0.0151 1.25 0.344 8.44E-4 0.07 0.9393 0.748 1939297 CBMicro_027356 COc1ccc(NC(=O)Cn2nc(c(Br)c2C)C(F)(F)F)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H19 compound treatment 0.368 0.0271 2.25 0.366 0.0228 2.02 3.0224 0.9986 1504219 CBMicro_027357 COc1ccccc1NC(=O)c2c(NC(=O)Cc3ccccc3)sc4CCCCCc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H20 compound treatment 0.337 -0.0039 -0.32 0.343 -1.56E-4 -0.01 -0.2387 -0.7367 1542438 CBMicro_027358 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc3ccccc3oc2=O)C(=O)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H21 compound treatment 0.341 1.0E-4 0.01 0.339 -0.00416 -0.37 -0.2546 -0.691 1506520 CBMicro_027359 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H22 compound treatment 0.335 -0.0059 -0.49 0.341 -0.00216 -0.19 -0.4815 -0.9157 1939298 CBMicro_027360 CCCN(C=O)/N=C/c1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H23 positive control 0.086 -0.255 -21.16 0.088 -0.255 -22.61 -30.9529 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 H24 positive control 0.092 -0.249 -20.66 0.099 -0.244 -21.64 -29.9113 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I01 mock treatment 0.343 0.0021 0.17 0.354 0.0108 0.96 0.8028 0.822 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I02 mock treatment 0.346 0.0051 0.42 0.348 0.00484 0.43 0.6029 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I03 compound treatment 0.356 0.0151 1.25 0.352 0.00884 0.78 1.4406 0.9744 1939299 CBMicro_027361 Brc1cccc(c1)N2C(=O)CC(N3CCC(Cc4ccccc4)CC3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I04 compound treatment 0.341 1.0E-4 0.01 0.343 -1.56E-4 -0.01 -0.0039 -0.2429 1939300 CBMicro_027362 Fc1ccccc1N2CCN(CC2)C3CC(=O)N(C3=O)c4cccc(Cl)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I05 compound treatment 0.352 0.0111 0.92 0.347 0.00384 0.34 0.8925 0.9084 1174163 CBMicro_027363 COc1cccc(c1)C(=O)NCc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I06 compound treatment 0.36 0.0191 1.59 0.348 0.00484 0.43 1.4248 0.8673 1939301 CBMicro_027364 CC(=O)c1c(O)c(cc(c1O)C(C)(C)C)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I07 compound treatment 0.349 0.0081 0.67 0.34 -0.00316 -0.28 0.2777 0.3813 1939302 CBMicro_027365 COc1ccc2n(C)c(SCc3ccc(Cl)cc3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I08 compound treatment 0.384 0.0431 3.58 0.387 0.0438 3.89 5.2776 0.9992 1199681 CBMicro_027366 Nc1nc2CCCCc2c(c1C#N)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I09 compound treatment 0.34 -9.0E-4 -0.07 0.356 0.0128 1.14 0.752 0.6593 1939303 CBMicro_027367 Nc1ccccc1C(=O)N/N=C\c2ccc(Br)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I10 compound treatment 0.339 -0.0019 -0.16 0.352 0.00884 0.78 0.4427 0.5537 1387357 CBMicro_027368 Cn1c(=O)n(Cc2ccc(Cl)cc2)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I11 compound treatment 0.347 0.0061 0.51 0.349 0.00584 0.52 0.7243 0.9999 1501305 CBMicro_027369 CCOC(=O)CSc1nc2cc(OCC)ccc2n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I12 compound treatment 0.347 0.0061 0.51 0.356 0.0128 1.14 1.1629 0.9335 1275996 CBMicro_027370 Clc1cccc(c1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I13 compound treatment 0.732 0.391 32.47 0.747 0.404 35.79 48.2658 0.9988 1939304 CBMicro_027371 CCOc1cc(/C=C/2\SC(=S)NC2=O)ccc1OC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I14 compound treatment 0.366 0.0251 2.08 0.368 0.0248 2.2 3.0303 0.9996 1939305 CBMicro_027372 FC(F)(F)c1ccc2SC(CC(=O)Nc3ccccc3Cl)C(=O)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I15 compound treatment 0.362 0.0211 1.75 0.359 0.0158 1.4 2.2315 0.994 1939306 CBMicro_027373 C=CCOc1cccc(/C=N/NC(=O)CC(=O)NC2CCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I16 compound treatment 0.397 0.0561 4.66 0.382 0.0388 3.44 5.7274 0.9889 1939307 CBMicro_027374 COc1ccc(NC(=O)/C(=C\c2ccccc2OC)/NC(=O)c3ccccc3OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I17 compound treatment 0.347 0.0061 0.51 0.347 0.00384 0.34 0.599 0.9814 1133193 CBMicro_027375 COc1cc(cc(OC)c1OC)C2NC(=S)NC(=C2C(=O)Nc3cccc(C)c3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I18 compound treatment 0.349 0.0081 0.67 0.349 0.00584 0.52 0.8417 0.9917 1939308 CBMicro_027376 COC(=O)C1(CC1)S(=O)(=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I19 compound treatment 0.363 0.0221 1.83 0.356 0.0128 1.14 2.1022 0.9736 1614172 CBMicro_027377 COc1ccc(cc1)n2cnc3cc(NS(=O)(=O)c4ccc(C)cc4)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I20 compound treatment 0.373 0.0321 2.66 0.371 0.0278 2.47 3.6292 0.9993 1939309 CBMicro_027378 CCOC(=O)c1c(NC(=O)CNCc2ccccc2)sc3CCCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I21 compound treatment 0.351 0.0101 0.84 0.353 0.00984 0.87 1.2098 0.9998 1575308 CBMicro_027379 COc1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c3ncccc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I22 compound treatment 0.381 0.0401 3.33 0.381 0.0378 3.35 4.7255 1.0 1677069 CBMicro_027380 COc1ccc(NC(=O)c2ccc(cc2)N(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I23 positive control 0.085 -0.256 -21.24 0.089 -0.254 -22.52 -30.9489 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 I24 positive control 0.093 -0.248 -20.58 0.093 -0.25 -22.17 -30.2286 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J01 mock treatment 0.307 -0.0339 -2.81 0.338 -0.00516 -0.46 -2.3132 -0.8113 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J02 mock treatment 0.342 0.0011 0.09 0.352 0.00884 0.78 0.6188 0.7842 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J03 compound treatment 0.343 0.0021 0.17 0.334 -0.00916 -0.81 -0.4505 -0.5428 1939310 CBMicro_027381 CC(C(=O)c1ccc(C)cc1)[n+]2cccc(c2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J04 compound treatment 0.353 0.0121 1.0 0.35 0.00684 0.61 1.1392 0.9708 1939311 CBMicro_027382 [O-][N+](=O)c1cccc(/C=N/NC(=O)C(=O)N2CCCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J05 compound treatment 0.403 0.0621 5.16 0.438 0.0948 8.41 9.5889 0.9725 1939312 CBMicro_027383 Oc1ccc(Cl)cc1/C=C\2/SC(=S)N(Cc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J06 compound treatment 0.338 -0.0029 -0.24 0.353 0.00984 0.87 0.4466 0.4935 1939313 CBMicro_027384 CCOC(=O)c1c(NC(=O)CNC(C)C)sc2CCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J07 compound treatment 0.34 -9.0E-4 -0.07 0.351 0.00784 0.7 0.4387 0.6275 1939314 CBMicro_027385 C/C(=N\O)/CCc1oc2ccc(C)cc2c1c3ccc(C)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J08 compound treatment 0.396 0.0551 4.57 0.397 0.0538 4.77 6.6087 0.9998 1484562 CBMicro_027386 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3)c(=O)n2C1c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J09 compound treatment 0.666 0.325 26.99 0.669 0.326 28.88 39.5035 0.9994 1939315 CBMicro_027387 OCCN1CCN(CC1)c2cc(ccc2[N+](=O)[O-])N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J10 compound treatment 0.568 0.227 18.85 0.595 0.252 22.32 29.1133 0.9965 1939316 CBMicro_027388 CCN1C(=O)/C(=C\c2ccc(O)cc2O)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J11 compound treatment 0.34 -9.0E-4 -0.07 0.349 0.00584 0.52 0.3134 0.5989 1939317 CBMicro_027389 CC(C)c1ccc(NC(=O)C(=O)NCCCN2CCOCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J12 compound treatment 0.368 0.0271 2.25 0.365 0.0218 1.94 2.9597 0.9972 1127619 CBMicro_027390 COc1ccc(OC)c(Nc2nc3nonc3nc2N4CCCCC4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J13 compound treatment 0.333 -0.0079 -0.66 0.351 0.00784 0.7 0.0278 0.0291 1425652 CBMicro_027391 COc1ccc(cc1)C2SC(C)C(=O)N2c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J14 compound treatment 0.395 0.0541 4.49 0.391 0.0478 4.24 6.174 0.9996 1939318 CBMicro_027392 Clc1ccc(/C=N/NC(=O)CN(Cc2ccccc2)Oc3ccccc3)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J15 compound treatment 0.346 0.0051 0.42 0.361 0.0178 1.58 1.4176 0.8659 1939319 CBMicro_027393 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)ccc1OCc4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J16 compound treatment 0.411 0.0701 5.82 0.422 0.0788 6.99 9.0559 0.9959 1939320 CBMicro_027394 CC(=O)c1cccc(NC(=O)c2nn3c(cc(nc3c2Cl)c4cccs4)C(F)(F)F)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J17 compound treatment 0.341 1.0E-4 0.01 0.344 8.44E-4 0.07 0.0587 0.7808 1316350 CBMicro_027395 O=C(NC1CCCCC1)C2COc3ccccc3O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J18 compound treatment 0.348 0.0071 0.59 0.345 0.00184 0.16 0.5323 0.8703 1939321 CBMicro_027396 Cc1cc(C)c2nc3sc(=Cc4cc5OCOc5cc4[N+](=O)[O-])c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J19 compound treatment 0.414 0.0731 6.07 0.399 0.0558 4.95 7.7907 0.9949 1939322 CBMicro_027397 CC1(C)Cc2ccccc2/C(=C(\C#N)/C(=O)Nc3cccc(c3)[N+](=O)[O-])/N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J20 compound treatment 0.375 0.0341 2.83 0.374 0.0308 2.73 3.9346 0.9998 1939323 CBMicro_027398 [O-][N+](=O)c1cc(Cl)ccc1N2CCN(CC2)C(=O)c3c(F)c(F)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J21 compound treatment 0.352 0.0111 0.92 0.348 0.00484 0.43 0.9551 0.9396 1939324 CBMicro_027399 COc1ccccc1NC(=O)C(=O)NNC(=O)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J22 compound treatment 0.38 0.0391 3.25 0.374 0.0308 2.73 4.2281 0.9963 1939325 CBMicro_027400 Cc1ccc(NC(=S)NNC(=O)CCn2c3ccccc3c4ccccc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J23 positive control 0.086 -0.255 -21.16 0.09 -0.253 -22.44 -30.8275 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 J24 positive control 0.094 -0.247 -20.5 0.095 -0.248 -21.99 -30.0446 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K01 mock treatment 0.338 -0.0029 -0.24 0.345 0.00184 0.16 -0.0547 -0.188 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K02 mock treatment 0.341 1.0E-4 0.01 0.341 -0.00216 -0.19 -0.1293 -0.6757 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K03 compound treatment 0.345 0.0041 0.34 0.34 -0.00316 -0.28 0.0429 0.0974 1358323 CBMicro_027401 Oc1c(CC(=O)N2CCOCC2)c(=O)[nH]c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K04 compound treatment 0.278 -0.0629 -5.22 0.282 -0.0612 -5.42 -7.5248 -0.9998 1643434 CBMicro_027402 Oc1ccc(Nc2nc(cs2)c3ccccn3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K05 compound treatment 0.345 0.0041 0.34 0.347 0.00384 0.34 0.4816 1.0 1939326 CBMicro_027403 COc1ccc(cc1)N2C(=O)CC(N3CCN(CC3)c4ccccc4F)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K06 compound treatment 0.372 0.0311 2.58 0.367 0.0238 2.11 3.3198 0.9951 1939327 CBMicro_027404 O=C/1N(C(=O)c2ccccc2\C1=C\N3CCOCC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K07 compound treatment 0.348 0.0071 0.59 0.335 -0.00816 -0.72 -0.0943 -0.1011 1438618 CBMicro_027405 Cc1cc(NC(=O)c2ccccc2)n(n1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K08 compound treatment 0.464 0.123 10.22 0.453 0.11 9.73 14.1097 0.9997 1169335 CBMicro_027406 CCOC(=O)C1=C(C)N=c2sc(=Cc3c(OC)ccc4ccccc34)c(=O)n2C1c5ccc6OCOc6c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K09 compound treatment 0.341 1.0E-4 0.01 0.337 -0.00616 -0.55 -0.3799 -0.6963 1939328 CBMicro_027407 COc1cccc(c1)C(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K10 compound treatment 0.326 -0.0149 -1.24 0.329 -0.0142 -1.25 -1.7618 -1.0 1939329 CBMicro_027408 OC(=O)C1Nc2ccc(cc2C3C=CCC31)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K11 compound treatment 0.411 0.0701 5.82 0.407 0.0638 5.66 8.1159 0.9999 1939330 CBMicro_027409 COc1ccc(N/C=C/C(=O)c2ccc(Cl)cc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K12 compound treatment 0.376 0.0351 2.91 0.375 0.0318 2.82 4.056 0.9999 1939331 CBMicro_027410 CCOC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(Br)cc2)C(=O)OCC)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K13 compound treatment 0.344 0.0031 0.26 0.342 -0.00116 -0.1 0.1095 0.3954 1578402 CBMicro_027411 COc1cccc(c1)n2cnc3cccc(N)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K14 compound treatment 0.344 0.0031 0.26 0.345 0.00184 0.16 0.2975 0.976 1161809 CBMicro_027412 COc1ccccc1N2CCN(CC2)C(=O)c3ccccc3I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K15 compound treatment 0.341 1.0E-4 0.01 0.342 -0.00116 -0.1 -0.0666 -0.6477 1939332 CBMicro_027413 CC1=NN(C(=O)COc2ccccc2)C(O)(C1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K16 compound treatment 0.353 0.0121 1.0 0.346 0.00284 0.25 0.8885 0.8579 1193889 CBMicro_027414 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K17 compound treatment 0.35 0.0091 0.76 0.351 0.00784 0.7 1.0257 0.9991 1781190 CBMicro_027415 CN(C)c1ccc(cc1)C(=O)NCc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K18 compound treatment 0.388 0.0471 3.91 0.408 0.0648 5.75 6.8284 0.9824 1939333 CBMicro_027416 O=C(Nc1ccc(cc1)N2CCCCC2)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K19 compound treatment 0.341 1.0E-4 0.01 0.339 -0.00416 -0.37 -0.2546 -0.691 1504335 CBMicro_027417 COc1ccc(OC)c(c1)S(=O)(=O)N2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K20 compound treatment 0.36 0.0191 1.59 0.352 0.00884 0.78 1.6754 0.9472 1939334 CBMicro_027418 CC1=C(C(NC(=S)N1)c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K21 compound treatment 0.443 0.102 8.48 0.435 0.0918 8.14 11.749 0.9998 1939335 CBMicro_027419 COc1cc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)ccc1OCC#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K22 compound treatment 0.573 0.232 19.27 0.572 0.229 20.28 27.9656 0.9997 1939336 CBMicro_027420 Cc1ccc(cc1)N2C(=O)/C(=C\Nn3cnnc3)/c4ccccc4C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K23 positive control 0.088 -0.253 -21.0 0.088 -0.255 -22.61 -30.8355 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 K24 positive control 0.094 -0.247 -20.5 0.097 -0.246 -21.81 -29.9192 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L01 mock treatment 0.339 -0.0019 -0.16 0.35 0.00684 0.61 0.3173 0.5064 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L02 mock treatment 0.342 0.0011 0.09 0.344 8.44E-4 0.07 0.1174 0.9951 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L03 compound treatment 0.396 0.0551 4.57 0.384 0.0408 3.62 5.794 0.9933 1250267 CBMicro_027421 S=C(Nc1cccc2ccccc12)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L04 compound treatment 0.347 0.0061 0.51 0.34 -0.00316 -0.28 0.1603 0.2771 1939337 CBMicro_027422 COCCCNC(=O)CC(=O)N/N=C/c1cccc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L05 compound treatment 0.356 0.0151 1.25 0.362 0.0188 1.67 2.0673 0.99 1939338 CBMicro_027423 CCC1=NN(C(=O)c2ccncc2)C(O)(C1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L06 compound treatment 0.339 -0.0019 -0.16 0.371 0.0278 2.47 1.6333 0.6606 1939339 CBMicro_027424 CCCCSc1nnc-2c(OC3(Nc4ccccc42)C(=O)Nc5ccc(Br)cc53)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L07 compound treatment 0.349 0.0081 0.67 0.346 0.00284 0.25 0.6537 0.9103 1939340 CBMicro_027425 CCCCNC(=O)c1c(O)c2ccccc2n(C)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L08 compound treatment 0.347 0.0061 0.51 0.348 0.00484 0.43 0.6616 0.9966 1741043 CBMicro_027426 Fc1ccc(cc1)c2nnc(NC(=O)c3ccc(Cl)cc3Cl)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L09 compound treatment 0.353 0.0121 1.0 0.347 0.00384 0.34 0.9512 0.8967 1255110 CBMicro_027427 COc1ccc(CCN2C(SCC2=O)c3ccc(Cl)c(Cl)c3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L10 compound treatment 0.407 0.0661 5.49 0.418 0.0748 6.63 8.5704 0.9956 1939341 CBMicro_027428 COc1cc(C=c2sc3nc4c(C)cc(C)cc4n3c2=O)cc(Br)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L11 compound treatment 0.38 0.0391 3.25 0.374 0.0308 2.73 4.2281 0.9963 1939342 CBMicro_027429 COC(=O)c1ccccc1NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L12 compound treatment 0.349 0.0081 0.67 0.344 8.44E-4 0.07 0.5284 0.7809 1939343 CBMicro_027430 CCCCNC(=O)Cn1nc(c(Br)c1C)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L13 compound treatment 0.386 0.0451 3.74 0.375 0.0318 2.82 4.643 0.9903 1939344 CBMicro_027431 FC(F)(F)c1cc(nc2cc(nn12)C(=O)Nc3ccncc3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L14 compound treatment 0.375 0.0341 2.83 0.37 0.0268 2.38 3.6839 0.9963 1939345 CBMicro_027432 Nc1c(C#N)c(nn1CCO)/C(=C/c2ccco2)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L15 compound treatment 0.387 0.0461 3.83 0.375 0.0318 2.82 4.7017 0.9888 1939346 CBMicro_027433 COc1ccc(/C=C/C(=O)Nc2ccc(cc2)N3CCOCC3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L16 compound treatment 0.334 -0.0069 -0.57 0.34 -0.00316 -0.28 -0.6028 -0.9457 1939347 CBMicro_027434 Sc1nnc(c2ccco2)n1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L17 compound treatment 0.349 0.0081 0.67 0.346 0.00284 0.25 0.6537 0.9103 1939348 CBMicro_027435 Cc1ccccc1OCCSc2nc3ccccc3n2CCO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L18 compound treatment 0.343 0.0021 0.17 0.347 0.00384 0.34 0.3641 0.9516 1488224 CBMicro_027436 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L19 compound treatment 0.375 0.0341 2.83 0.369 0.0258 2.29 3.6213 0.9945 1736047 CBMicro_027437 CCOc1ccc(cc1)c2nnc(NC(=O)CSCc3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L20 compound treatment 0.371 0.0301 2.5 0.369 0.0258 2.29 3.3865 0.9991 1939349 CBMicro_027438 CCOc1cc(Br)c(Br)c(/C=C\2/SC(=O)NC2=O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L21 compound treatment 0.362 0.0211 1.75 0.349 0.00584 0.52 1.6048 0.8786 1703408 CBMicro_027439 COC(=O)C1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L22 compound treatment 0.805 0.464 38.53 0.81 0.467 41.37 56.499 0.9994 1939350 CBMicro_027440 CC1CN(CCN1S(=O)(=O)C)c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L23 positive control 0.09 -0.251 -20.83 0.088 -0.255 -22.61 -30.718 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 L24 positive control 0.101 -0.24 -19.92 0.096 -0.247 -21.9 -29.571 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M01 mock treatment 0.338 -0.0029 -0.24 0.342 -0.00116 -0.1 -0.2427 -0.9275 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M02 mock treatment 0.338 -0.0029 -0.24 0.342 -0.00116 -0.1 -0.2427 -0.9275 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M03 compound treatment 0.345 0.0041 0.34 0.342 -0.00116 -0.1 0.1682 0.4733 1939351 CBMicro_027441 OC(=O)c1ccc(cc1)N2C(=O)CC(N3CCN(CC3)c4ccccc4F)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M04 compound treatment 0.352 0.0111 0.92 0.343 -1.56E-4 -0.01 0.6418 0.6964 1939352 CBMicro_027442 Brc1cccc(c1)N2C(=O)CC(N3CCN(CC3)C(c4ccccc4)c5ccccc5)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M05 compound treatment 0.291 -0.0499 -4.14 0.313 -0.0302 -2.67 -4.819 -0.9775 1939353 CBMicro_027443 Cc1ccc2nc([nH]c2c1)/C(=C\c3ccc(o3)[N+](=O)[O-])/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M06 compound treatment 0.351 0.0101 0.84 0.346 0.00284 0.25 0.7711 0.8807 1410912 CBMicro_027444 COc1ccc(OC)c(NC(=O)c2ccc(OC)cc2OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M07 compound treatment 0.351 0.0101 0.84 0.343 -1.56E-4 -0.01 0.5831 0.6953 1467611 CBMicro_027445 OC(=O)C1CC=CCC1C(=O)Nc2cccc(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M08 compound treatment 0.352 0.0111 0.92 0.348 0.00484 0.43 0.9551 0.9396 1373941 CBMicro_027446 COc1ccc(cc1OC)C(=O)Nc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M09 compound treatment 0.349 0.0081 0.67 0.345 0.00184 0.16 0.591 0.8541 1107193 CBMicro_027447 CC1C(O)C(C)C(N(C)C1c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M10 compound treatment 0.335 -0.0059 -0.49 0.338 -0.00516 -0.46 -0.6695 -0.9994 1939354 CBMicro_027448 CNS(=O)(=O)c1ccccc1C(=O)NNC2=NS(=O)(=O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M11 compound treatment 0.386 0.0451 3.74 0.421 0.0778 6.9 7.5256 0.9588 1939355 CBMicro_027449 CCN(CC)c1ccc(/C=C/2\SC(=N)NC2=O)c(OCc3ccc(Cl)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M12 compound treatment 0.646 0.305 25.33 0.636 0.293 25.95 36.2615 0.9999 1939356 CBMicro_027450 OC(=O)c1cc(ccc1Cl)c2ccc(/C=N/Nc3ccc(Cl)cc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M13 compound treatment 0.369 0.0281 2.33 0.364 0.0208 1.85 2.9557 0.9933 1939357 CBMicro_027451 C/C(=N\O)/CCc1oc2c(Br)cc(Br)cc2c1c3ccc(C)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M14 compound treatment 0.355 0.0141 1.17 0.345 0.00184 0.16 0.9433 0.7981 1939358 CBMicro_027452 Oc1ccccc1/C=C/2\C(=O)Oc3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M15 compound treatment 0.344 0.0031 0.26 0.337 -0.00616 -0.55 -0.2038 -0.3379 1939359 CBMicro_027453 CC1=NN(C(=O)c2ccccc2Cl)C(O)(C1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M16 compound treatment 0.334 -0.0069 -0.57 0.337 -0.00616 -0.55 -0.7908 -0.9997 1392681 CBMicro_027454 COc1cc(cc(OC)c1OC)C2NC(=S)NC(=C2C(=O)Nc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M17 compound treatment 0.398 0.0571 4.74 0.38 0.0368 3.27 5.6608 0.9834 1939360 CBMicro_027455 Oc1ccc(/C=N/Nc2nncc(n2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M18 compound treatment 0.345 0.0041 0.34 0.341 -0.00216 -0.19 0.1056 0.2704 1366485 CBMicro_027456 Cc1ccc(cc1C)S(=O)(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M19 compound treatment 0.402 0.0611 5.07 0.377 0.0338 3.0 5.7076 0.9686 1939361 CBMicro_027457 CCOc1ccc(NC(=O)/C(=C\c2ccccc2Cl)/NC(=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M20 compound treatment 0.365 0.0241 2.0 0.373 0.0298 2.64 3.2849 0.9905 1119192 CBMicro_027458 COc1ccc(cc1)C(=O)Nc2nnc(Cc3ccc(OC)c(OC)c3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M21 compound treatment 0.393 0.0521 4.33 0.375 0.0318 2.82 5.0539 0.9786 1476188 CBMicro_027459 Cc1ccc(NC(=O)CC2Sc3ccccc3NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M22 compound treatment 0.347 0.0061 0.51 0.344 8.44E-4 0.07 0.411 0.8028 1939362 CBMicro_027460 CC(=NNC(=O)CN(C1=NS(=O)(=O)c2ccccc12)c3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M23 positive control 0.088 -0.253 -21.0 0.09 -0.253 -22.44 -30.7101 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 M24 positive control 0.094 -0.247 -20.5 0.096 -0.247 -21.9 -29.9819 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N01 mock treatment 0.347 0.0061 0.51 0.346 0.00284 0.25 0.5363 0.9481 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N02 mock treatment 0.344 0.0031 0.26 0.35 0.00684 0.61 0.6108 0.9271 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N03 compound treatment 0.346 0.0051 0.42 0.346 0.00284 0.25 0.4776 0.9693 1939363 CBMicro_027461 S=C(NCC1(CC2CC3CC(C2)CC1)C3)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N04 compound treatment 0.377 0.0361 3.0 0.372 0.0288 2.56 3.9267 0.9969 1420854 CBMicro_027462 Clc1ccccc1C2NC(=O)c3sc(=S)n(c3N2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N05 compound treatment 0.391 0.0501 4.16 0.404 0.0608 5.39 6.7538 0.9918 1939364 CBMicro_027463 Brc1ccccc1C(=O)ON=C2C=CC(=O)C=C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N06 compound treatment 0.353 0.0121 1.0 0.351 0.00784 0.7 1.2018 0.9838 1781412 CBMicro_027464 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=O)c3ccc(cc3)[N+](=O)[O-])sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N07 compound treatment 0.35 0.0091 0.76 0.345 0.00184 0.16 0.6497 0.8406 1939365 CBMicro_027465 O=C1CC(CC(=O)C1=CNC2CCCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N08 compound treatment 0.387 0.0461 3.83 0.382 0.0388 3.44 5.1404 0.9986 1939366 CBMicro_027466 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(cc3)C(=O)O)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N09 compound treatment 0.362 0.0211 1.75 0.345 0.00184 0.16 1.3542 0.7697 1939367 CBMicro_027467 COc1ccc(CNC(=O)/C=C/c2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N10 compound treatment 0.379 0.0381 3.16 0.381 0.0378 3.35 4.6081 0.9996 1520657 CBMicro_027468 CC(C)(C)c1csc(NC(=O)C(c2ccccc2)c3ccccc3)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N11 compound treatment 0.359 0.0181 1.5 0.342 -0.00116 -0.1 0.9901 0.6574 1431114 CBMicro_027469 COc1ccc(cc1OC)c2nnc(NC(=O)c3ccc(F)cc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N12 compound treatment 0.351 0.0101 0.84 0.352 0.00884 0.78 1.1471 0.9994 1939368 CBMicro_027470 COc1cccc(/C=N/NC(=O)C(=O)N2CCCCCC2)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N13 compound treatment 0.405 0.0641 5.32 0.384 0.0408 3.62 6.3224 0.9824 1939369 CBMicro_027471 CCOc1ccc(Oc2cc(NC(=O)c3ccco3)cc(c2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N14 compound treatment 0.358 0.0171 1.42 0.343 -1.56E-4 -0.01 0.994 0.7002 1939370 CBMicro_027472 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N15 compound treatment 0.598 0.257 21.34 0.585 0.242 21.43 30.2478 1.0 1939371 CBMicro_027473 CC(=C1C(=O)c2ccccc2C1=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N16 compound treatment 0.358 0.0171 1.42 0.355 0.0118 1.05 1.746 0.989 1529447 CBMicro_027474 O=C1NC(Nc2c1sc(=S)n2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N17 compound treatment 0.368 0.0271 2.25 0.371 0.0278 2.47 3.3357 0.9989 1939372 CBMicro_027475 CCCCSc1nnc-2c(OC3(Nc4ccccc42)C(=O)Nc5ccc(F)cc53)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N18 compound treatment 0.353 0.0121 1.0 0.347 0.00384 0.34 0.9512 0.8967 1244614 CBMicro_027476 CCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(OC)c(OC)c2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N19 compound treatment 0.357 0.0161 1.34 0.343 -1.56E-4 -0.01 0.9353 0.6997 1939373 CBMicro_027477 Brc1ccc(cc1)C2=C/C(=C/c3ccc4OCOc4c3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N20 compound treatment 0.404 0.0631 5.24 0.404 0.0608 5.39 7.517 0.9999 1939374 CBMicro_027478 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)ccc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N21 compound treatment 0.377 0.0361 3.0 0.373 0.0298 2.64 3.9894 0.9981 1939375 CBMicro_027479 CSc1ccc(/C=C\2/SC(=O)N(CN3CCOCC3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N22 compound treatment 0.361 0.0201 1.67 0.349 0.00584 0.52 1.5461 0.8849 1146480 CBMicro_027480 CCOC(=O)c1sc(NC(=O)C2COc3ccccc3O2)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N23 positive control 0.088 -0.253 -21.0 0.09 -0.253 -22.44 -30.7101 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 N24 positive control 0.093 -0.248 -20.58 0.094 -0.249 -22.08 -30.1659 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O01 mock treatment 0.344 0.0031 0.26 0.348 0.00484 0.43 0.4855 0.9701 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O02 mock treatment 0.343 0.0021 0.17 0.346 0.00284 0.25 0.3015 0.9838 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O03 compound treatment 0.364 0.0231 1.92 0.352 0.00884 0.78 1.9102 0.9221 1939376 CBMicro_027481 FC(F)(F)c1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O04 compound treatment 0.35 0.0091 0.76 0.348 0.00484 0.43 0.8377 0.9641 1939377 CBMicro_027482 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)NCC4CCCO4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O05 compound treatment 0.343 0.0021 0.17 0.348 0.00484 0.43 0.4268 0.9212 1939378 CBMicro_027483 O=C(N1CCOCC1)c2ccc3nc4c5ccccc5c6ccccc6c4nc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O06 compound treatment 0.352 0.0111 0.92 0.351 0.00784 0.7 1.1431 0.9903 1939379 CBMicro_027484 CCCn1c(=O)c(C(=O)NNC(=O)COc2ccccc2)c(O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O07 compound treatment 0.448 0.107 8.89 0.441 0.0978 8.67 12.4185 0.9999 1939380 CBMicro_027485 Cn1c(/C=N/Nc2nc3ccccc3[nH]2)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O08 compound treatment 0.397 0.0561 4.66 0.406 0.0628 5.57 7.2314 0.996 1939381 CBMicro_027486 O=C/1C(=CC(Nc2ccccc2)\C1=C/c3ccccc3)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O09 compound treatment 0.38 0.0391 3.25 0.358 0.0148 1.32 3.2255 0.9209 1247743 CBMicro_027487 C(Oc1ccc(cc1)C2Nc3cccc4cccc(N2)c34)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O10 compound treatment 0.349 0.0081 0.67 0.344 8.44E-4 0.07 0.5284 0.7809 1679381 CBMicro_027488 Cn1c(=O)c(C(=O)NC2CCCCC2)c(O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O11 compound treatment 0.47 0.129 10.72 0.466 0.123 10.89 15.2766 1.0 1939382 CBMicro_027489 COC(=O)C1(CC(=O)C(C)(C)C)NN=C(S1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O12 compound treatment 0.352 0.0111 0.92 0.343 -1.56E-4 -0.01 0.6418 0.6964 1939383 CBMicro_027490 CCOC(=O)C1CCN(CC1)C2CC(=O)N(C2=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O13 compound treatment 0.372 0.0311 2.58 0.37 0.0268 2.38 3.5078 0.9992 1939384 CBMicro_027491 Clc1ccc(Nc2nc(cs2)c3cccs3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O14 compound treatment 0.349 0.0081 0.67 0.343 -1.56E-4 -0.01 0.4657 0.6924 1647327 CBMicro_027492 COc1ccc(OC)c(c1)S(=O)(=O)n2ccnc2C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O15 compound treatment 0.385 0.0441 3.66 0.392 0.0488 4.33 5.6496 0.9965 1939385 CBMicro_027493 O=C(N/N=C/c1nc2ccccc2n1Cc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O16 compound treatment 0.35 0.0091 0.76 0.349 0.00584 0.52 0.9004 0.983 1549523 CBMicro_027494 CCOc1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O17 compound treatment 0.351 0.0101 0.84 0.343 -1.56E-4 -0.01 0.5831 0.6953 1592986 CBMicro_027495 COc1ccc(cc1OC)C(=O)N2CCCc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O18 compound treatment 0.353 0.0121 1.0 0.355 0.0118 1.05 1.4525 0.9998 1139586 CBMicro_027496 COc1ccc2n(Cc3ccccc3)c(SCC(=O)c4ccc(OC)c(OC)c4)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O19 compound treatment 0.389 0.0481 3.99 0.337 -0.00616 -0.55 2.4378 0.6049 1939386 CBMicro_027497 CCOC(=O)C1CCN(CC1)C2CC(=O)N(C2=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O20 compound treatment 0.345 0.0041 0.34 0.348 0.00484 0.43 0.5442 0.9934 1939387 CBMicro_027498 O=C(CN1C(=O)c2cccc3cccc(C1=O)c23)NCCN4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O21 compound treatment 0.386 0.0451 3.74 0.384 0.0408 3.62 5.207 0.9999 1939388 CBMicro_027499 COc1ccccc1NC(=O)/C(=C\c2ccc(Br)cc2)/NC(=O)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O22 compound treatment 0.353 0.0121 1.0 0.35 0.00684 0.61 1.1392 0.9708 1147478 CBMicro_027500 CN1c2ccccc2N(C)C1(C)c3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O23 positive control 0.086 -0.255 -21.16 0.091 -0.252 -22.35 -30.7649 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 O24 positive control 0.093 -0.248 -20.58 0.094 -0.249 -22.08 -30.1659 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P01 mock treatment 0.345 0.0041 0.34 0.345 0.00184 0.16 0.3562 0.9435 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P02 mock treatment 0.346 0.0051 0.42 0.346 0.00284 0.25 0.4776 0.9693 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P03 compound treatment 0.358 0.0171 1.42 0.347 0.00384 0.34 1.2447 0.8526 1939389 CBMicro_027501 COc1ccc2ccccc2c1/C=C/3\SC(=S)N(Cc4ccccc4)C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P04 compound treatment 0.378 0.0371 3.08 0.368 0.0248 2.2 3.7347 0.9865 1939390 CBMicro_027502 CC(C)c1cc(C)ccc1OCCSc2nc3ccccc3n2CCO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P05 compound treatment 0.446 0.105 8.73 0.458 0.115 10.18 13.3664 0.9971 1939391 CBMicro_027503 NC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P06 compound treatment 0.358 0.0171 1.42 0.359 0.0158 1.4 1.9967 1.0 1459525 CBMicro_027504 Clc1ccc(NC(=O)C2CN(C(=O)C2)c3ccc(Br)cc3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P07 compound treatment 0.312 -0.0289 -2.4 0.281 -0.0622 -5.51 -5.5916 -0.9306 1939392 CBMicro_027505 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(C3=O)c4ccc(cc4)[N+](=O)[O-])o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P08 compound treatment 0.348 0.0071 0.59 0.35 0.00684 0.61 0.8457 0.9999 1681323 CBMicro_027506 Clc1ccc(cc1)N(C2CCS(=O)(=O)C2)C(=O)Nc3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P09 compound treatment 0.371 0.0301 2.5 0.368 0.0248 2.2 3.3238 0.998 1939393 CBMicro_027507 COc1cc(/C=N/NC(=O)N)ccc1Oc2nc(Nc3ccc(C)cc3Br)nc(n2)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P10 compound treatment 0.393 0.0521 4.33 0.4 0.0568 5.04 6.6206 0.9971 1939394 CBMicro_027508 CN(c1ccccc1)c2ccc(cc2)C3NN=C(S3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P11 compound treatment 0.347 0.0061 0.51 0.347 0.00384 0.34 0.599 0.9814 1417096 CBMicro_027509 CCCSc1nc2ccccc2n1CCO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P12 compound treatment 0.368 0.0271 2.25 0.376 0.0328 2.91 3.649 0.9919 1688348 CBMicro_027510 CC1CC(Nc2ccc(C)cc2)c3cc(C)ccc3N1C(=O)c4ccc(F)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P13 compound treatment 0.348 0.0071 0.59 0.349 0.00584 0.52 0.783 0.9979 1939395 CBMicro_027511 Cc1cc(nn1CC(=O)Nc2ccccc2C(F)(F)F)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P14 compound treatment 0.443 0.102 8.48 0.437 0.0938 8.32 11.8743 1.0 1426316 CBMicro_027512 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P15 compound treatment 0.347 0.0061 0.51 0.348 0.00484 0.43 0.6616 0.9966 1939396 CBMicro_027513 Cc1cc(C)c2nc3sc(=Cc4cccc(Br)c4)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P16 compound treatment 0.35 0.0091 0.76 0.352 0.00884 0.78 1.0884 0.9998 1780253 CBMicro_027514 [O-][N+](=O)c1cccc(c1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P17 compound treatment 0.383 0.0421 3.5 0.375 0.0318 2.82 4.4669 0.9944 1432900 CBMicro_027515 CCC(=O)Nc1sc2CC(C)CCc2c1C(=O)Nc3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P18 compound treatment 0.355 0.0141 1.17 0.338 -0.00516 -0.46 0.5046 0.4016 1214704 CBMicro_027516 Fc1ccccc1C(=O)Nc2ccc(OCC(=O)N3CCOCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P19 compound treatment 0.346 0.0051 0.42 0.343 -1.56E-4 -0.01 0.2896 0.6836 1251562 CBMicro_027517 Nc1nonc1C(=O)OCc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P20 compound treatment 0.364 0.0231 1.92 0.353 0.00984 0.87 1.9729 0.9364 1939397 CBMicro_027518 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C\3/C(=O)Nc4ccccc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P21 compound treatment 0.35 0.0091 0.76 0.351 0.00784 0.7 1.0257 0.9991 1939398 CBMicro_027519 FC(F)(F)c1ccccc1/C=N/NC(=O)C(=O)NCc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P22 compound treatment 0.352 0.0111 0.92 0.348 0.00484 0.43 0.9551 0.9396 1939399 CBMicro_027520 Clc1ccc(/C=N/N(Cc2ccccc2)C=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P23 positive control 0.088 -0.253 -21.0 0.091 -0.252 -22.35 -30.6475 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.771 P24 positive control 0.095 -0.246 -20.41 0.096 -0.247 -21.9 -29.9232 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A01 mock treatment 0.327 -0.0141 -1.17 0.325 -0.00945 -0.84 -1.4179 -0.9867 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A02 mock treatment 0.332 -0.00906 -0.75 0.335 5.48E-4 0.05 -0.4978 -0.6601 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A03 compound treatment 0.336 -0.00506 -0.42 0.334 -4.52E-4 -0.04 -0.3256 -0.7709 1660831 CBMicro_027521 Nc1nonc1C(=O)OCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A04 compound treatment 0.333 -0.00806 -0.67 0.336 0.00155 0.14 -0.3764 -0.5507 1637709 CBMicro_027522 CCOC(=O)c1[nH]cnc1C(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A05 compound treatment 0.331 -0.0101 -0.84 0.331 -0.00345 -0.31 -0.8071 -0.9071 1939400 CBMicro_027523 C/C(=N\N1C(N(Cc2ccccc2)CC1=O)c3ccccc3)/c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A06 compound treatment 0.334 -0.00706 -0.59 0.331 -0.00345 -0.31 -0.631 -0.954 1939401 CBMicro_027524 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=O)Cn2nnc(n2)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A07 compound treatment 0.345 0.00394 0.33 0.343 0.00855 0.76 0.7667 0.9293 1939402 CBMicro_027525 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCOCC3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A08 compound treatment 0.333 -0.00806 -0.67 0.322 -0.0125 -1.1 -1.2537 -0.9713 1939403 CBMicro_027526 CC1=C(C(NC(=O)N1)c2cccs2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A09 compound treatment 0.331 -0.0101 -0.84 0.33 -0.00445 -0.39 -0.8698 -0.9413 1120642 CBMicro_027527 O=C(N1CCOCC1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A10 compound treatment 0.329 -0.0121 -1.0 0.322 -0.0125 -1.1 -1.4885 -0.9988 1494857 CBMicro_027528 CC(=O)Nc1nc2CC(C)(C)CNC(=O)c2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A11 compound treatment 0.333 -0.00806 -0.67 0.323 -0.0115 -1.01 -1.191 -0.9796 1338736 CBMicro_027529 Fc1ccc(cc1)c2nnc(NC(=O)Nc3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A12 compound treatment 0.345 0.00394 0.33 0.341 0.00655 0.58 0.6414 0.9631 1939404 CBMicro_027530 COc1cccc(/C=C/2\SC(=O)N(C2=O)c3ccc(Cl)cc3)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A13 compound treatment 0.297 -0.0441 -3.66 0.233 -0.101 -8.99 -8.9442 -0.9215 1939405 CBMicro_027531 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(C3=O)c4cccc(c4)C(F)(F)F)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A14 compound treatment 0.326 -0.0151 -1.25 0.315 -0.0195 -1.72 -2.1033 -0.9876 1272424 CBMicro_027532 CNC(=S)NCCc1ccc(OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A15 compound treatment 0.338 -0.00306 -0.25 0.326 -0.00845 -0.75 -0.7095 -0.897 1939406 CBMicro_027533 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(OC)c(Cl)c3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A16 compound treatment 0.327 -0.0141 -1.17 0.322 -0.0125 -1.1 -1.6059 -0.9996 1939407 CBMicro_027534 CN1/C(=C\C(=O)Nc2ccccc2Br)/c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A17 compound treatment 0.338 -0.00306 -0.25 0.332 -0.00245 -0.22 -0.3335 -0.9969 1605146 CBMicro_027535 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(F)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A18 compound treatment 0.336 -0.00506 -0.42 0.336 0.00155 0.14 -0.2003 -0.4528 1939408 CBMicro_027536 COc1ccc(/C=C/C(=O)n2nc(C)cc2C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A19 compound treatment 0.333 -0.00806 -0.67 0.33 -0.00445 -0.39 -0.7524 -0.9682 1939409 CBMicro_027537 CCOC(=O)c1cccc(c1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A20 compound treatment 0.336 -0.00506 -0.42 0.334 -4.52E-4 -0.04 -0.3256 -0.7709 1939410 CBMicro_027538 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCOCC3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A21 compound treatment 0.336 -0.00506 -0.42 0.307 -0.0275 -2.43 -2.0176 -0.8172 1939411 CBMicro_027539 OCCNCC(O)Cn1c2ccc(I)cc2c3cc(I)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A22 compound treatment 0.325 -0.0161 -1.33 0.325 -0.00945 -0.84 -1.5353 -0.9749 1357104 CBMicro_027540 CC(=O)Nc1nc2CCCC(=O)c2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A23 positive control 0.084 -0.257 -21.34 0.083 -0.251 -22.28 -30.8478 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 A24 positive control 0.085 -0.256 -21.26 0.086 -0.248 -22.02 -30.6011 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B01 mock treatment 0.318 -0.0231 -1.91 0.33 -0.00445 -0.39 -1.6329 -0.8353 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B02 mock treatment 0.34 -0.00106 -0.09 0.338 0.00355 0.31 0.1599 0.4894 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B03 compound treatment 0.344 0.00294 0.24 0.343 0.00855 0.76 0.708 0.8897 1632047 CBMicro_027541 Cc1cc(C)cc(c1)N(CC(=O)NCc2ccco2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B04 compound treatment 0.347 0.00594 0.49 0.342 0.00755 0.67 0.8215 0.9887 1658484 CBMicro_027542 Oc1cccc(NC(=O)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B05 compound treatment 0.395 0.0539 4.48 0.374 0.0395 3.5 5.6445 0.9927 1939412 CBMicro_027543 Oc1ccc(cc1/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B06 compound treatment 0.375 0.0339 2.82 0.372 0.0375 3.33 4.3451 0.9966 1939413 CBMicro_027544 CSc1ccc(/C=C\2/SC(=O)N(CN3CCCCC3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B07 compound treatment 0.338 -0.00306 -0.25 0.327 -0.00745 -0.66 -0.6469 -0.914 1739259 CBMicro_027545 Fc1ccc(CN2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B08 compound treatment 0.336 -0.00506 -0.42 0.326 -0.00845 -0.75 -0.8269 -0.9627 1274747 CBMicro_027546 Cc1cc(C)c2nc3sc(=Cc4ccc(o4)c5ccccc5C(=O)O)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B09 compound treatment 0.354 0.0129 1.07 0.345 0.0105 0.93 1.4204 0.9976 1503875 CBMicro_027547 CCCC(=O)Nc1sc(C)c(C)c1C(=O)Nc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B10 compound treatment 0.325 -0.0161 -1.33 0.315 -0.0195 -1.72 -2.162 -0.992 1939414 CBMicro_027548 Sc1nc2ccccc2n1CCOc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B11 compound treatment 0.342 9.35E-4 0.08 0.337 0.00255 0.23 0.2146 0.8986 1939415 CBMicro_027549 Clc1ccc(c2nnc(SCC(=O)NC3CCCCC3)o2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B12 compound treatment 0.336 -0.00506 -0.42 0.326 -0.00845 -0.75 -0.8269 -0.9627 1939416 CBMicro_027550 CC(=O)Oc1c(c2ccccc2)c3nc4ccccc4nc3c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B13 compound treatment 0.345 0.00394 0.33 0.344 0.00955 0.85 0.8294 0.9143 1243375 CBMicro_027551 CCOc1cccc2sc(NC(=O)C(C)C)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B14 compound treatment 0.353 0.0119 0.99 0.346 0.0115 1.02 1.4243 0.9999 1939417 CBMicro_027552 COc1ccc(NC(=O)c2nn3c(cc(nc3c2Br)c4cccs4)C(F)(F)F)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B15 compound treatment 0.355 0.0139 1.16 0.342 0.00755 0.67 1.2911 0.9661 1351637 CBMicro_027553 CC(C)(C)c1ccc2[nH]c3C(=O)CCCc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B16 compound treatment 0.349 0.00794 0.66 0.337 0.00255 0.23 0.6255 0.8982 1939418 CBMicro_027554 C/C(=N\N1C(N(Cc2ccccc2)CC1=O)c3ccc(Br)cc3)/c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B17 compound treatment 1.058 0.717 59.52 1.035 0.701 62.08 85.9864 0.9998 1939419 CBMicro_027555 CC[n+]1c(/C=C/c2ccc(OC)cc2)sc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B18 compound treatment 0.336 -0.00506 -0.42 0.331 -0.00345 -0.31 -0.5136 -0.9878 1939420 CBMicro_027556 C1CC(=NN1c2ccccc2)/N=C/N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B19 compound treatment 0.34 -0.00106 -0.09 0.335 5.48E-4 0.05 -0.0281 -0.2789 1939421 CBMicro_027557 CC(CC(=O)Nc1cc(C)ccc1C)Cc2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B20 compound treatment 0.338 -0.00306 -0.25 0.339 0.00455 0.4 0.1051 0.2206 1350553 CBMicro_027558 O=C1CNC(=O)c2c(N1)ncn2Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B21 compound treatment 0.336 -0.00506 -0.42 0.344 0.00955 0.85 0.301 0.3186 1939422 CBMicro_027559 OS(=O)(=O)c1nc2ccccc2n1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B22 compound treatment 0.354 0.0129 1.07 0.345 0.0105 0.93 1.4204 0.9976 1939423 CBMicro_027560 OC1(CC(=NN1C(=S)c2ccccc2)c3ccccc3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B23 positive control 0.084 -0.257 -21.34 0.084 -0.25 -22.2 -30.7851 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 B24 positive control 0.084 -0.257 -21.34 0.085 -0.249 -22.11 -30.7224 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C01 mock treatment 0.341 -6.45E-5 -0.01 0.338 0.00355 0.31 0.2186 0.695 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C02 mock treatment 0.343 0.00194 0.16 0.338 0.00355 0.31 0.336 0.9514 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C03 compound treatment 0.346 0.00494 0.41 0.341 0.00655 0.58 0.7001 0.9855 1939424 CBMicro_027561 [O-][N+](=O)c1ccc(c2ccc(C=c3sc4nc5cc(Br)cnc5n4c3=O)o2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C04 compound treatment 0.354 0.0129 1.07 0.346 0.0115 1.02 1.483 0.9997 1939425 CBMicro_027562 COc1nc(Nc2ccc(cc2)C(=O)C)nc(OC)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C05 compound treatment 0.32 -0.0211 -1.75 0.314 -0.0205 -1.81 -2.5182 -0.9998 1939426 CBMicro_027563 Clc1ccc(CSCCNC(=S)Nc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C06 compound treatment 0.399 0.0579 4.81 0.377 0.0425 3.77 6.0673 0.9927 1939427 CBMicro_027564 Cc1cc(cc(C)c1O)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C07 compound treatment 0.351 0.00994 0.82 0.344 0.00955 0.85 1.1816 0.9999 1292537 CBMicro_027565 CC(C)c1ccccc1NC(=O)C2CN(C(=O)C2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C08 compound treatment 0.35 0.00894 0.74 0.345 0.0105 0.93 1.1856 0.9934 1496394 CBMicro_027566 COC(=O)c1ccc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C09 compound treatment 0.352 0.0109 0.91 0.342 0.00755 0.67 1.115 0.9887 1780348 CBMicro_027567 COc1ccc(CCN2C(SCC2=O)c3ccccc3[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C10 compound treatment 0.33 -0.0111 -0.92 0.314 -0.0205 -1.81 -1.9311 -0.9504 1939428 CBMicro_027568 COc1ccccc1OCCSc2nc3ccc(Br)cc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C11 compound treatment 0.313 -0.0281 -2.33 0.301 -0.0335 -2.96 -3.7437 -0.9929 1939429 CBMicro_027569 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C12 compound treatment 0.323 -0.0181 -1.5 0.314 -0.0205 -1.81 -2.342 -0.9956 1939430 CBMicro_027570 Sc1nc2ccccc2n1CCOc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C13 compound treatment 0.342 9.35E-4 0.08 0.335 5.48E-4 0.05 0.0893 0.9745 1780193 CBMicro_027571 Cc1c(Br)c(nn1CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C14 compound treatment 0.523 0.182 15.1 0.509 0.175 15.47 21.6183 0.9999 1939431 CBMicro_027572 Cc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C/c3ccco3)/S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C15 compound treatment 0.346 0.00494 0.41 0.334 -4.52E-4 -0.04 0.2614 0.635 1562035 CBMicro_027573 C[N+]1=C(CC(=O)Nc2ccccc2Cl)c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C16 compound treatment 0.351 0.00994 0.82 0.345 0.0105 0.93 1.2443 0.9981 1647299 CBMicro_027574 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C17 compound treatment 0.35 0.00894 0.74 0.342 0.00755 0.67 0.9976 0.9987 1939432 CBMicro_027575 Cc1cc(nn1CC(=O)Nc2sc3CCCCc3c2C#N)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C18 compound treatment 0.424 0.0829 6.89 0.465 0.131 11.57 13.0494 0.9693 1939433 CBMicro_027576 CCN1C(=O)/C(=C\c2cc(Br)cc([N+](=O)[O-])c2O)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C19 compound treatment 0.343 0.00194 0.16 0.341 0.00655 0.58 0.524 0.8702 1939434 CBMicro_027577 CSc1ccccc1NC(=O)Cn2nc(cc2C)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C20 compound treatment 0.337 -0.00406 -0.34 0.348 0.0135 1.2 0.6104 0.4894 1939435 CBMicro_027578 Cc1cc(C)c(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C21 compound treatment 0.344 0.00294 0.24 0.346 0.0115 1.02 0.896 0.8517 1939436 CBMicro_027579 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCC3CCCO3)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C22 compound treatment 0.258 -0.0831 -6.9 0.258 -0.0765 -6.78 -9.667 -1.0 1939437 CBMicro_027580 COc1ccc(N/C(=C\C(=O)Nc2ccccc2)/C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C23 positive control 0.082 -0.259 -21.51 0.082 -0.252 -22.37 -31.0278 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 C24 positive control 0.087 -0.254 -21.09 0.089 -0.245 -21.75 -30.2957 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D01 mock treatment 0.345 0.00394 0.33 0.337 0.00255 0.23 0.3907 0.9837 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D02 mock treatment 0.344 0.00294 0.24 0.334 -4.52E-4 -0.04 0.144 0.5832 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D03 compound treatment 0.346 0.00494 0.41 0.336 0.00155 0.14 0.3868 0.8951 1674641 CBMicro_027581 Cn1c(CNC2CCCCC2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D04 compound treatment 0.346 0.00494 0.41 0.348 0.0135 1.2 1.1387 0.8976 1939438 CBMicro_027582 COc1ccc(CNC(=O)c2cnn3c(cc(nc23)c4ccccc4)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D05 compound treatment 0.341 -6.45E-5 -0.01 0.345 0.0105 0.93 0.6572 0.703 1939439 CBMicro_027583 CCOC(=O)N1CCN(CC1)C2CC(=O)N(C2=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D06 compound treatment 0.329 -0.0121 -1.0 0.323 -0.0115 -1.01 -1.4258 -1.0 1939440 CBMicro_027584 Oc1ccc(cc1)C2NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D07 compound treatment 0.353 0.0119 0.99 0.345 0.0105 0.93 1.3617 0.9996 1939441 CBMicro_027585 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D08 compound treatment 0.381 0.0399 3.32 0.366 0.0315 2.8 4.3213 0.9964 1939442 CBMicro_027586 [O-][N+](=O)c1cccc(Cl)c1C2NN=C(Cc3ccccc3)S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D09 compound treatment 0.371 0.0299 2.49 0.368 0.0335 2.97 3.8596 0.996 1444238 CBMicro_027587 Cc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D10 compound treatment 0.338 -0.00306 -0.25 0.329 -0.00545 -0.48 -0.5215 -0.9551 1939443 CBMicro_027588 CC(=O)CSc1nnnn1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D11 compound treatment 0.343 0.00194 0.16 0.34 0.00555 0.49 0.4613 0.8918 1939444 CBMicro_027589 CC(C)N1C(=O)c2cccc3c(ccc(C1=O)c23)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D12 compound treatment 0.337 -0.00406 -0.34 0.334 -4.52E-4 -0.04 -0.2669 -0.7855 1776486 CBMicro_027590 COc1ccccc1NC(=O)/C=C/2\N(C)C(C)(C)Cc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D13 compound treatment 0.356 0.0149 1.24 0.358 0.0235 2.09 2.3524 0.9691 1939445 CBMicro_027591 CC(=O)N(CCc1ccccc1)C2(CC=C)CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D14 compound treatment 0.391 0.0499 4.15 0.371 0.0365 3.24 5.2217 0.9925 1939446 CBMicro_027592 COCc1cc(C)nc(NNC(=S)Nc2ccccc2)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D15 compound treatment 0.36 0.0189 1.57 0.35 0.0155 1.38 2.0859 0.9978 1939447 CBMicro_027593 CCCCCc1nnc(NC(=O)COc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D16 compound treatment 0.342 9.35E-4 0.08 0.334 -4.52E-4 -0.04 0.0266 0.3046 1939448 CBMicro_027594 Clc1cc2OCOc2cc1C=C3C(=O)NC(=S)NC3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D17 compound treatment 0.373 0.0319 2.65 0.366 0.0315 2.8 3.8517 0.9996 1939449 CBMicro_027595 Clc1ccc(Sc2c(nc3sccn23)c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D18 compound treatment 0.35 0.00894 0.74 0.35 0.0155 1.38 1.4989 0.9578 1425654 CBMicro_027596 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=O)COc3ccccc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D19 compound treatment 0.35 0.00894 0.74 0.351 0.0165 1.47 1.5615 0.9501 1244511 CBMicro_027597 OC(=O)c1ccc(cc1)c2ccc(C=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D20 compound treatment 0.351 0.00994 0.82 0.348 0.0135 1.2 1.4323 0.9832 1441042 CBMicro_027598 CN(CCC(=O)NC1CC(C)(C)N(C)C(C)(C)C1)C2CC(C)(C)N(C)C(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D21 compound treatment 0.385 0.0439 3.65 0.366 0.0315 2.8 4.5561 0.9914 1939450 CBMicro_027599 COc1cc(/C=C\2/SC(=S)NC2=O)c(cc1OC)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D22 compound treatment 0.342 9.35E-4 0.08 0.341 0.00655 0.58 0.4653 0.7947 1776487 CBMicro_027600 Cc1ccc(NC(=O)/C(=C/2\NC(C)(C)Cc3ccccc23)/C#N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D23 positive control 0.079 -0.262 -21.76 0.082 -0.252 -22.37 -31.204 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 D24 positive control 0.086 -0.255 -21.18 0.087 -0.247 -21.93 -30.4797 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E01 mock treatment 0.331 -0.0101 -0.84 0.326 -0.00845 -0.75 -1.1204 -0.9985 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E02 mock treatment 0.343 0.00194 0.16 0.33 -0.00445 -0.39 -0.1653 -0.3881 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E03 compound treatment 0.35 0.00894 0.74 0.343 0.00855 0.76 1.0602 0.9999 1587121 CBMicro_027601 OCc1nc2ccccc2n1CCOc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E04 compound treatment 0.339 -0.00206 -0.17 0.338 0.00355 0.31 0.1012 0.2825 1939451 CBMicro_027602 COc1ccc(cc1C2NN=C(S2)c3ccccc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E05 compound treatment 0.34 -0.00106 -0.09 0.332 -0.00245 -0.22 -0.2161 -0.9214 1777217 CBMicro_027603 Cc1cc(C)c2nc3sc(=Cc4ccc(cc4)[N+](=O)[O-])c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E06 compound treatment 0.343 0.00194 0.16 0.34 0.00555 0.49 0.4613 0.8918 1508446 CBMicro_027604 CCCC1=C(C(NC(=O)N1)c2ccccc2Cl)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E07 compound treatment 0.344 0.00294 0.24 0.332 -0.00245 -0.22 0.0187 0.0573 1939452 CBMicro_027605 CC(=O)Oc1c(c2ccc(Cl)cc2)c3nc4ccccc4nc3c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E08 compound treatment 0.372 0.0309 2.57 0.355 0.0205 1.82 3.1037 0.9858 1939453 CBMicro_027606 CC1=C(C(NC(=S)N1)c2ccc(Br)cc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E09 compound treatment 0.351 0.00994 0.82 0.339 0.00455 0.4 0.8683 0.9458 1939454 CBMicro_027607 CN(C)/N=C/c1c(C)nn(c1O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E10 compound treatment 0.361 0.0199 1.66 0.351 0.0165 1.47 2.2073 0.9982 1939455 CBMicro_027608 COc1ccc(/C=C/C(=O)Nc2ccc(OC)cc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E11 compound treatment 0.363 0.0219 1.82 0.339 0.00455 0.4 1.5727 0.8432 1515873 CBMicro_027609 Fc1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E12 compound treatment 0.339 -0.00206 -0.17 0.339 0.00455 0.4 0.1638 0.374 1777738 CBMicro_027610 CSc1ccccc1NC(=O)Cn2nc(cc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E13 compound treatment 0.341 -6.45E-5 -0.01 0.343 0.00855 0.76 0.5319 0.7021 1939456 CBMicro_027611 CC(=O)/C=C\1/SCC(=O)N1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E14 compound treatment 0.338 -0.00306 -0.25 0.345 0.0105 0.93 0.4811 0.4966 1939457 CBMicro_027612 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCN3CCOCC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E15 compound treatment 0.315 -0.0261 -2.16 0.3 -0.0345 -3.05 -3.689 -0.9858 1939458 CBMicro_027613 COc1ccc(OCCSc2nnnn2c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E16 compound treatment 0.346 0.00494 0.41 0.345 0.0105 0.93 0.9507 0.9315 1164839 CBMicro_027614 O=C(NC1CCCC1)c2ccc(CN(c3ccccn3)S(=O)(=O)c4ccccc4)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E17 compound treatment 0.357 0.0159 1.32 0.363 0.0285 2.53 2.7245 0.9543 1287360 CBMicro_027615 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=O)c3ccccc3Cl)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E18 compound treatment 0.333 -0.00806 -0.67 0.325 -0.00945 -0.84 -1.0657 -0.9938 1939459 CBMicro_027616 [O-][N+](=O)c1ccc(COC(=O)CSc2nc3ccccc3s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E19 compound treatment 0.384 0.0429 3.56 0.384 0.0495 4.39 5.6254 0.9946 1939460 CBMicro_027617 Cc1ccc(o1)C2(C)NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E20 compound treatment 0.51 0.169 14.02 0.483 0.149 13.16 19.2259 0.9995 1939461 CBMicro_027618 [O-][N+](=O)c1ccc(NCCCNS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E21 compound treatment 0.349 0.00794 0.66 0.343 0.00855 0.76 1.0015 0.9976 1939462 CBMicro_027619 CC1=NN(C(=O)c2ccccc2)C(C)(O)C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E22 compound treatment 0.344 0.00294 0.24 0.342 0.00755 0.67 0.6453 0.9064 1683071 CBMicro_027620 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E23 positive control 0.081 -0.26 -21.59 0.083 -0.251 -22.28 -31.0239 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 E24 positive control 0.086 -0.255 -21.18 0.091 -0.243 -21.58 -30.229 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F01 mock treatment 0.338 -0.00306 -0.25 0.329 -0.00545 -0.48 -0.5215 -0.9551 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F02 mock treatment 0.34 -0.00106 -0.09 0.332 -0.00245 -0.22 -0.2161 -0.9214 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F03 compound treatment 0.345 0.00394 0.33 0.333 -0.00145 -0.13 0.1401 0.3989 1591999 CBMicro_027621 C=CCC(Nc1ccccc1)c2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F04 compound treatment 0.342 9.35E-4 0.08 0.334 -4.52E-4 -0.04 0.0266 0.3046 1939463 CBMicro_027622 CCOc1cc(/C=N/NC(=O)c2cccs2)ccc1OCc3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F05 compound treatment 0.35 0.00894 0.74 0.339 0.00455 0.4 0.8096 0.9589 1163670 CBMicro_027623 Cc1ccc(o1)c2c(C#N)c(N)nc3CCCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F06 compound treatment 0.345 0.00394 0.33 0.341 0.00655 0.58 0.6414 0.9631 1939464 CBMicro_027624 Clc1ccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F07 compound treatment 0.343 0.00194 0.16 0.341 0.00655 0.58 0.524 0.8702 1346082 CBMicro_027625 O=C1C2C3C=CC(C2C(=O)N1c4ccncc4)C53CC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F08 compound treatment 0.343 0.00194 0.16 0.327 -0.00745 -0.66 -0.3533 -0.5199 1939465 CBMicro_027626 [O-][N+](=O)c1ccccc1c2ccc(C=c3sc4nc5cc(Br)cnc5n4c3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F09 compound treatment 0.34 -0.00106 -0.09 0.332 -0.00245 -0.22 -0.2161 -0.9214 1563429 CBMicro_027627 COc1ccc(OC)c(c1)S(=O)(=O)N2CCN(C)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F10 compound treatment 0.466 0.125 10.37 0.459 0.125 11.04 15.139 0.9995 1939466 CBMicro_027628 COC(=O)C/1=C(C)N(C)C(=O)\C1=C/c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F11 compound treatment 0.475 0.134 11.12 0.469 0.135 11.92 16.2939 0.9994 1782417 CBMicro_027629 Cn1c2nc(cn2c3ccccc13)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F12 compound treatment 0.35 0.00894 0.74 0.327 -0.00745 -0.66 0.0576 0.058 1592808 CBMicro_027630 O=C1N(CCS(=O)(=O)NCc2ccccc2)C(=O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F13 compound treatment 0.351 0.00994 0.82 0.352 0.0175 1.56 1.6829 0.956 1939467 CBMicro_027631 COc1ccc(OC)c(NC(=O)C(=O)NNC(=O)c2cccs2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F14 compound treatment 0.347 0.00594 0.49 0.325 -0.00945 -0.84 -0.2439 -0.2509 1939468 CBMicro_027632 OC(C(=O)NCCCCOc1ccccc1)(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F15 compound treatment 0.348 0.00694 0.58 0.343 0.00855 0.76 0.9428 0.9908 1779873 CBMicro_027633 CCC(=O)N1C(C)CC(N(C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-])c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F16 compound treatment 0.495 0.154 12.78 0.47 0.136 12.01 17.5307 0.9995 1939469 CBMicro_027634 CC1(NN=C(S1)c2ccccc2)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F17 compound treatment 0.34 -0.00106 -0.09 0.341 0.00655 0.58 0.3479 0.5926 1939470 CBMicro_027635 COc1cc(cc(OC)c1OC)C2NC(=S)NC(=C2C(=O)Nc3ccc(Br)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F18 compound treatment 0.349 0.00794 0.66 0.344 0.00955 0.85 1.0642 0.9923 1939471 CBMicro_027636 Cc1nn(c(O)c1C=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F19 compound treatment 0.401 0.0599 4.98 0.385 0.0505 4.48 6.686 0.9986 1468646 CBMicro_027637 Clc1ccccc1NC(=O)Nc2cccc3cccnc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F20 compound treatment 0.346 0.00494 0.41 0.344 0.00955 0.85 0.8881 0.9446 1778415 CBMicro_027638 COc1cc(NC(=O)c2cc3nc(cc(C)n3n2)c4ccccc4)cc(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F21 compound treatment 0.343 0.00194 0.16 0.341 0.00655 0.58 0.524 0.8702 1333726 CBMicro_027639 O=C(Nc1ccc(cc1)C2CCCCC2)C3=C4Nc5ccccc5N4CCC3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F22 compound treatment 0.337 -0.00406 -0.34 0.331 -0.00345 -0.31 -0.4549 -0.9988 1939472 CBMicro_027640 CC1=NN(C(=N)c2ccccc2)C(O)(C1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F23 positive control 0.085 -0.256 -21.26 0.085 -0.249 -22.11 -30.6637 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 F24 positive control 0.088 -0.253 -21.01 0.089 -0.245 -21.75 -30.237 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G01 mock treatment 0.337 -0.00406 -0.34 0.329 -0.00545 -0.48 -0.5802 -0.9846 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G02 mock treatment 0.334 -0.00706 -0.59 0.325 -0.00945 -0.84 -1.007 -0.9848 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G03 compound treatment 0.337 -0.00406 -0.34 0.335 5.48E-4 0.05 -0.2042 -0.5991 1939473 CBMicro_027641 [O-][N+](=O)c1ccc(cc1)C2NC(=O)c3sc(=S)n(c3N2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G04 compound treatment 0.378 0.0369 3.07 0.37 0.0355 3.15 4.3959 0.9999 1939474 CBMicro_027642 CCOC(=O)CC(=O)c1cc(C(=O)C)c(Nc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G05 compound treatment 0.348 0.00694 0.58 0.342 0.00755 0.67 0.8802 0.9972 1556602 CBMicro_027643 CC(C)C(=O)N1C(C)CC(Nc2ccc(C)cc2)c3cc(C)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G06 compound treatment 0.339 -0.00206 -0.17 0.332 -0.00245 -0.22 -0.2748 -0.9931 1301724 CBMicro_027644 Cc1ccc2c(nc3sc(=Cc4cc5OCOc5cc4Br)c(=O)n32)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G07 compound treatment 0.349 0.00794 0.66 0.334 -4.52E-4 -0.04 0.4375 0.6629 1488467 CBMicro_027645 CC(C)N1C(C)CC(O)N1C(=O)CC#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G08 compound treatment 0.344 0.00294 0.24 0.333 -0.00145 -0.13 0.0814 0.2952 1103055 CBMicro_027646 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(cc2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G09 compound treatment 0.341 -6.45E-5 -0.01 0.328 -0.00645 -0.57 -0.4081 -0.7137 1939475 CBMicro_027647 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(F)c(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G10 compound treatment 0.34 -0.00106 -0.09 0.339 0.00455 0.4 0.2225 0.5393 1939476 CBMicro_027648 Cc1ccc(c2ccc(/C=C/3\Sc4ccccc4C3=O)o2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G11 compound treatment 0.365 0.0239 1.99 0.348 0.0135 1.2 2.2541 0.9709 1939477 CBMicro_027649 Brc1ccc(cc1)C2=C/C(=C/c3cccs3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G12 compound treatment 0.582 0.241 20.0 0.554 0.22 19.46 27.9017 0.9999 1939478 CBMicro_027650 CCOC(=O)CC1(C)NN=C(S1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G13 compound treatment 0.354 0.0129 1.07 0.339 0.00455 0.4 1.0444 0.9105 1939479 CBMicro_027651 [O-][N+](=O)c1cccc(c1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G14 compound treatment 0.338 -0.00306 -0.25 0.333 -0.00145 -0.13 -0.2709 -0.9501 1939480 CBMicro_027652 Cc1c([N+](=O)[O-])c(nn1CC(=O)N2CCOCC2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G15 compound treatment 0.342 9.35E-4 0.08 0.336 0.00155 0.14 0.1519 0.9637 1939481 CBMicro_027653 Brc1cccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G16 compound treatment 0.361 0.0199 1.66 0.343 0.00855 0.76 1.706 0.9373 1341533 CBMicro_027654 COC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G17 compound treatment 0.385 0.0439 3.65 0.374 0.0395 3.5 5.0575 0.9998 1939482 CBMicro_027655 COc1ccc(cc1)c2c(C)nn3c(cc(nc23)C(F)(F)F)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G18 compound treatment 0.347 0.00594 0.49 0.336 0.00155 0.14 0.4455 0.8709 1345417 CBMicro_027656 CCc1cccc(C)c1NC(=O)CSc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G19 compound treatment 0.344 0.00294 0.24 0.331 -0.00345 -0.31 -0.044 -0.1124 1939483 CBMicro_027657 Cc1nn(CC(=O)Nc2c(F)cc(F)cc2Br)c(C)c1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G20 compound treatment 0.355 0.0139 1.16 0.357 0.0225 2.0 2.2311 0.9662 1939484 CBMicro_027658 Cc1cc(nn1CC(=O)Nc2ccc(Cl)cc2Cl)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G21 compound treatment 0.401 0.0599 4.98 0.38 0.0455 4.04 6.3727 0.9946 1707342 CBMicro_027659 COc1ccccc1C2NC(=O)c3sc(=S)n(c3N2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G22 compound treatment 0.342 9.35E-4 0.08 0.337 0.00255 0.23 0.2146 0.8986 1700629 CBMicro_027660 CCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G23 positive control 0.085 -0.256 -21.26 0.085 -0.249 -22.11 -30.6637 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 G24 positive control 0.09 -0.251 -20.84 0.091 -0.243 -21.58 -29.9942 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H01 mock treatment 0.34 -0.00106 -0.09 0.327 -0.00745 -0.66 -0.5294 -0.7947 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H02 mock treatment 0.332 -0.00906 -0.75 0.325 -0.00945 -0.84 -1.1244 -0.9986 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H03 compound treatment 0.339 -0.00206 -0.17 0.335 5.48E-4 0.05 -0.0868 -0.4874 1149192 CBMicro_027661 CCOc1ccc2nc(NC(=O)c3ccccc3C(=O)O)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H04 compound treatment 0.34 -0.00106 -0.09 0.334 -4.52E-4 -0.04 -0.0908 -0.9358 1420145 CBMicro_027662 O=C(CC(CC(=O)c1nc2ccccc2s1)c3ccccn3)c4nc5ccccc5s4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H05 compound treatment 0.335 -0.00606 -0.5 0.336 0.00155 0.14 -0.259 -0.4963 1549063 CBMicro_027663 COc1ccc(cc1)n2c(S)nnc2c3cc(OC)c(OC)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H06 compound treatment 0.341 -6.45E-5 -0.01 0.335 5.48E-4 0.05 0.0306 0.6254 1939485 CBMicro_027664 CCCCNC(=O)Cn1nc(cc1C)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H07 compound treatment 0.333 -0.00806 -0.67 0.327 -0.00745 -0.66 -0.9404 -1.0 1030972 CBMicro_027665 S=C(NCc1ccco1)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H08 compound treatment 0.297 -0.0441 -3.66 0.291 -0.0435 -3.85 -5.3096 -0.9997 1939486 CBMicro_027666 Clc1ccc(Cn2nnc(n2)c3ccccc3Cl)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H09 compound treatment 0.363 0.0219 1.82 0.35 0.0155 1.38 2.262 0.9905 1939487 CBMicro_027667 Oc1ccc(/C=N/N2C(=O)c3ccccc3C2=O)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H10 compound treatment 0.346 0.00494 0.41 0.342 0.00755 0.67 0.7627 0.9723 1939488 CBMicro_027668 CNC(=S)N(C)/N=C/C(=O)c1ccccc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H11 compound treatment 0.328 -0.0131 -1.08 0.318 -0.0165 -1.46 -1.7979 -0.9894 1688235 CBMicro_027669 Cn1c(CNc2ccccc2O)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H12 compound treatment 0.361 0.0199 1.66 0.331 -0.00345 -0.31 0.954 0.5668 1519124 CBMicro_027670 CC1CCc2c(C(=O)Nc3cccc(Cl)c3)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H13 compound treatment 0.353 0.0119 0.99 0.359 0.0245 2.18 2.239 0.9366 1191944 CBMicro_027671 CCOC(=O)c1c(C)nc2n(CC=C)c3ccccc3n12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H14 compound treatment 0.38 0.0389 3.23 0.384 0.0495 4.39 5.3906 0.9886 1939489 CBMicro_027672 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCOCC4)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H15 compound treatment 0.35 0.00894 0.74 0.35 0.0155 1.38 1.4989 0.9578 1663780 CBMicro_027673 CCOc1ccc(OCC)c(c1)c2c(C#N)c(N)nc3CCCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H16 compound treatment 0.437 0.0959 7.96 0.439 0.105 9.27 12.1833 0.9972 1939490 CBMicro_027674 COc1cc(Br)cc(/C=N/NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H17 compound treatment 0.333 -0.00806 -0.67 0.319 -0.0155 -1.37 -1.4417 -0.9458 1594744 CBMicro_027675 Cc1ccc(Br)cc1S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H18 compound treatment 0.533 0.192 15.93 0.485 0.151 13.34 20.7014 0.9961 1939491 CBMicro_027676 Cc1cc(/C=C(/C(=O)c2ccccc2)\c3nc4ccccc4[nH]3)c(C)n1c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H19 compound treatment 0.336 -0.00506 -0.42 0.336 0.00155 0.14 -0.2003 -0.4528 1272680 CBMicro_027677 CCOc1cc(ccc1OCc2ccccc2)C(=S)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H20 compound treatment 0.374 0.0329 2.73 0.358 0.0235 2.09 3.4091 0.9911 1939492 CBMicro_027678 [O-][N+](=O)c1ccc(Sc2c(nc3sccn23)c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H21 compound treatment 0.339 -0.00206 -0.17 0.333 -0.00145 -0.13 -0.2122 -0.99 1939493 CBMicro_027679 Cc1ccc(/N=C/c2c(O)c(cc3oc4CCCCc4c23)[N+](=O)[O-])cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H22 compound treatment 0.334 -0.00706 -0.59 0.325 -0.00945 -0.84 -1.007 -0.9848 1939494 CBMicro_027680 CN(C)CCCN1C(SCC1=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H23 positive control 0.085 -0.256 -21.26 0.085 -0.249 -22.11 -30.6637 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 H24 positive control 0.091 -0.25 -20.76 0.092 -0.242 -21.49 -29.8729 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I01 mock treatment 0.35 0.00894 0.74 0.338 0.00355 0.31 0.7469 0.927 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I02 mock treatment 0.344 0.00294 0.24 0.341 0.00655 0.58 0.5827 0.9257 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I03 compound treatment 0.4 0.0589 4.89 0.4 0.0655 5.81 7.5673 0.9964 1720425 CBMicro_027681 O=C(Nc1nc(cs1)c2ccccc2)c3ccc(cc3)S(=O)(=O)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I04 compound treatment 0.343 0.00194 0.16 0.317 -0.0175 -1.55 -0.98 -0.6303 1939495 CBMicro_027682 CC(C)CC(NC(=O)/C(=C/c1ccccc1F)/NC(=O)c2ccccc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I05 compound treatment 0.351 0.00994 0.82 0.349 0.0145 1.29 1.4949 0.9767 1939496 CBMicro_027683 CC1CCN(CC1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I06 compound treatment 0.352 0.0109 0.91 0.35 0.0155 1.38 1.6163 0.9795 1623983 CBMicro_027684 CC1CC(Nc2ccc(C)cc2)c3cc(C)ccc3N1C(=O)CN4C(=O)c5ccccc5C4=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I07 compound treatment 0.41 0.0689 5.72 0.398 0.0635 5.63 8.029 1.0 1276466 CBMicro_027685 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4cccc(c4)C(=O)O)c(=O)n2C1c5ccc(OC)c(OC)c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I08 compound treatment 0.361 0.0199 1.66 0.332 -0.00245 -0.22 1.0166 0.6091 1509193 CBMicro_027686 COc1ccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc4CC(C)CCc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I09 compound treatment 0.345 0.00394 0.33 0.331 -0.00345 -0.31 0.0147 0.0329 1939497 CBMicro_027687 [O-][N+](=O)c1ccc(cc1)C2NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I10 compound treatment 0.343 0.00194 0.16 0.355 0.0205 1.82 1.4013 0.7665 1939498 CBMicro_027688 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccco4)cc(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I11 compound treatment 0.494 0.153 12.7 0.503 0.169 14.94 19.5399 0.9967 1939499 CBMicro_027689 CC1(C)Cc2ccccc2/C(=C/C(=S)Nc3ccccc3)/N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I12 compound treatment 0.354 0.0129 1.07 0.338 0.00355 0.31 0.9817 0.8773 1939500 CBMicro_027690 CCCCSc1nnc-2c(OC(Nc3ccccc32)c4ccc(O)cc4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I13 compound treatment 0.546 0.205 17.01 0.548 0.214 18.93 25.4124 0.9986 1939501 CBMicro_027691 Cc1cc(/C=N/NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c(C)n1c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I14 compound treatment 0.333 -0.00806 -0.67 0.348 0.0135 1.2 0.3756 0.2732 1939502 CBMicro_027692 CCSC(C)CC1C/C(=N/O)/c2c(CC)noc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I15 compound treatment 0.36 0.0189 1.57 0.356 0.0215 1.91 2.4619 0.9953 1939503 CBMicro_027693 CC(=O)/C=C\1/SC=C(N1c2ccccc2)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I16 compound treatment 0.353 0.0119 0.99 0.331 -0.00345 -0.31 0.4844 0.4671 1204665 CBMicro_027694 CCCC1=C(C(NC(=O)N1)c2ccc3OCOc3c2)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I17 compound treatment 0.359 0.0179 1.49 0.353 0.0185 1.64 2.2152 0.9988 1313077 CBMicro_027695 CCCC1=C(C(NC(=O)N1)c2ccc(OC)cc2OC)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I18 compound treatment 0.37 0.0289 2.4 0.364 0.0295 2.62 3.5503 0.9991 1407789 CBMicro_027696 CCOc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I19 compound treatment 0.408 0.0669 5.56 0.402 0.0675 5.99 8.1623 0.9993 1939504 CBMicro_027697 O=C(CSCc1ccccc1)Nc2nnc(/C=C/c3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I20 compound treatment 0.363 0.0219 1.82 0.353 0.0185 1.64 2.45 0.9987 1939505 CBMicro_027698 Clc1ccc(/C=C(/NC(=O)c2ccco2)\c3nc4ccccc4[nH]3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I21 compound treatment 0.357 0.0159 1.32 0.349 0.0145 1.29 1.8471 0.9999 1939506 CBMicro_027699 Nc1cn(C2OC(CO)C(O)C(O)C2O)c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I22 compound treatment 0.37 0.0289 2.4 0.362 0.0275 2.44 3.4249 1.0 1939507 CBMicro_027700 CCOC(=O)/C(=C\c1ccncc1)/C(=O)c2cc(C(=O)C)c(Nc3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I23 positive control 0.086 -0.255 -21.18 0.085 -0.249 -22.11 -30.605 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 I24 positive control 0.092 -0.249 -20.68 0.091 -0.243 -21.58 -29.8768 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J01 mock treatment 0.328 -0.0131 -1.08 0.294 -0.0405 -3.58 -3.3018 -0.8816 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J02 mock treatment 0.352 0.0109 0.91 0.35 0.0155 1.38 1.6163 0.9795 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J03 compound treatment 0.399 0.0579 4.81 0.374 0.0395 3.5 5.8793 0.9879 1217631 CBMicro_027701 CCOC(=O)COc1cc(Br)c(cc1OC)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J04 compound treatment 0.351 0.00994 0.82 0.33 -0.00445 -0.39 0.3043 0.3328 1192415 CBMicro_027702 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2Cl)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J05 compound treatment 0.383 0.0419 3.48 0.364 0.0295 2.62 4.3134 0.9901 1939508 CBMicro_027703 CC(=O)c1cccc(NC(=O)/C(=C\c2cccnc2)/NC(=O)c3ccc(C)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J06 compound treatment 0.532 0.191 15.85 0.517 0.183 16.18 22.648 0.9999 1939509 CBMicro_027704 CCOc1cc(Br)cc(/C=C\2/SC(=S)NC2=O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J07 compound treatment 0.35 0.00894 0.74 0.341 0.00655 0.58 0.9349 0.9926 1082249 CBMicro_027705 OC(=O)CN1C(=O)C2CC=CCC2C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J08 compound treatment 0.383 0.0419 3.48 0.366 0.0315 2.8 4.4387 0.9941 1939510 CBMicro_027706 COc1ccc(/C=C/C(=O)OCC(=O)c2cccc(c2)[N+](=O)[O-])cc1S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J09 compound treatment 0.363 0.0219 1.82 0.347 0.0125 1.11 2.074 0.972 1619780 CBMicro_027707 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccc(O)c(O)c4)C(=O)c5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J10 compound treatment 0.66 0.319 26.48 0.644 0.31 27.43 38.1204 0.9998 1939511 CBMicro_027708 OC(=O)c1ccccc1c2ccc(/C=C/3\S/C(=N\c4ccccc4)/N(C3=O)c5ccccc5)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J11 compound treatment 0.527 0.186 15.44 0.525 0.191 16.89 22.8558 0.999 1939512 CBMicro_027709 COc1cc(Br)c(/C=C\2/SC(=S)NC2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J12 compound treatment 0.359 0.0179 1.49 0.346 0.0115 1.02 1.7766 0.9833 1939513 CBMicro_027710 CCCN/N=C/c1c(C)nn(c1O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J13 compound treatment 0.333 -0.00806 -0.67 0.313 -0.0215 -1.9 -1.8177 -0.9018 1343489 CBMicro_027711 N(c1nc(cs1)c2ccccn2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J14 compound treatment 0.39 0.0489 4.06 0.38 0.0455 4.04 5.727 1.0 1939514 CBMicro_027712 COc1ccc(/C=C/C(=O)NCCSCc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J15 compound treatment 0.341 -6.45E-5 -0.01 0.337 0.00255 0.23 0.1559 0.6901 1939515 CBMicro_027713 Cc1cc(cc(C)c1N)C(O)(C(F)(F)F)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J16 compound treatment 0.344 0.00294 0.24 0.337 0.00255 0.23 0.332 0.9993 1939516 CBMicro_027714 Cc1ccc(cc1)n2c(S)nnc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J17 compound treatment 0.355 0.0139 1.16 0.347 0.0125 1.11 1.6044 0.9998 1554413 CBMicro_027715 O=C(CCN1C(=O)c2ccccc2C1=O)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J18 compound treatment 0.347 0.00594 0.49 0.332 -0.00245 -0.22 0.1948 0.3617 1939517 CBMicro_027716 C(C1=NNC(S1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J19 compound treatment 0.415 0.0739 6.14 0.408 0.0735 6.52 8.9492 0.9995 1165467 CBMicro_027717 Cc1ccc(s1)c2c(C#N)c(N)nc3CCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J20 compound treatment 0.486 0.145 12.03 0.474 0.14 12.37 17.253 0.9999 1939518 CBMicro_027718 Nc1c(C#N)c(nn1CCO)/C(=C/c2c[nH]c3ccccc23)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J21 compound treatment 0.377 0.0359 2.98 0.369 0.0345 3.06 4.2745 0.9999 1939519 CBMicro_027719 O=c1c(=NNc2c[nH]c(=O)[nH]c2=O)c(=O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J22 compound treatment 0.354 0.0129 1.07 0.355 0.0205 1.82 2.047 0.9683 1939520 CBMicro_027720 COc1ccc(/C=C/C(=O)Nc2ccc(OC)c(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J23 positive control 0.086 -0.255 -21.18 0.086 -0.248 -22.02 -30.5424 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 J24 positive control 0.092 -0.249 -20.68 0.092 -0.242 -21.49 -29.8142 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K01 mock treatment 0.346 0.00494 0.41 0.335 5.48E-4 0.05 0.3241 0.7855 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K02 mock treatment 0.341 -6.45E-5 -0.01 0.332 -0.00245 -0.22 -0.1574 -0.7243 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K03 compound treatment 0.347 0.00594 0.49 0.346 0.0115 1.02 1.0721 0.9439 1939521 CBMicro_027721 OC(=O)c1ccc(cc1)c2ccc(/C=N/NC(=O)Cn3nnc(n3)c4ccccc4)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K04 compound treatment 0.383 0.0419 3.48 0.375 0.0405 3.59 5.0027 0.9999 1939522 CBMicro_027722 OCCN1CCN(CC1)c2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K05 compound treatment 0.355 0.0139 1.16 0.344 0.00955 0.85 1.4164 0.9882 1939523 CBMicro_027723 CCOc1cc(cc(/C=C\2/SC(=S)NC2=O)c1O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K06 compound treatment 0.344 0.00294 0.24 0.33 -0.00445 -0.39 -0.1066 -0.23 1939524 CBMicro_027724 Cc1cc(c2ccccc2)n(n1)C(=S)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K07 compound treatment 0.362 0.0209 1.74 0.357 0.0225 2.0 2.642 0.9976 1939525 CBMicro_027725 Brc1ccccc1C(=O)Nc2nnc(/C=C/c3ccccc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K08 compound treatment 0.351 0.00994 0.82 0.341 0.00655 0.58 0.9936 0.9852 1939526 CBMicro_027726 CC(=O)OCCNC(=O)/C(=C\c1ccc(Br)cc1)/NC(=O)c2ccc(Br)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K09 compound treatment 0.4 0.0589 4.89 0.379 0.0445 3.95 6.2513 0.9943 1939527 CBMicro_027727 CCc1ccc2NC(=O)C3(NN=C(S3)c4ccccc4)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K10 compound treatment 0.301 -0.0401 -3.33 0.318 -0.0165 -1.46 -3.3829 -0.9315 1939528 CBMicro_027728 [O-][N+](=O)c1ccc(/C=C/C(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K11 compound treatment 0.241 -0.1 -8.31 0.234 -0.1 -8.9 -12.1689 -0.9994 1939529 CBMicro_027729 CCN1C(=O)/C(=C\c2ccc(o2)c3cccc(Cl)c3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K12 compound treatment 0.351 0.00994 0.82 0.345 0.0105 0.93 1.2443 0.9981 1939530 CBMicro_027730 COc1ccc(/C=C/C(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K13 compound treatment 0.393 0.0519 4.31 0.379 0.0445 3.95 5.8404 0.999 1434375 CBMicro_027731 CC1CCc2c(C(=O)Nc3ccccc3C)c(NC(=O)Cc4ccccc4)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K14 compound treatment 0.383 0.0419 3.48 0.376 0.0415 3.68 5.0654 0.9996 1939531 CBMicro_027732 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCc3cccnc3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K15 compound treatment 0.396 0.0549 4.56 0.391 0.0565 5.01 6.7685 0.9989 1939532 CBMicro_027733 Clc1ccc(Cn2cc(/C=N/N=C\3/NC(=O)CS3)c(n2)c4ccccc4)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K16 compound treatment 0.345 0.00394 0.33 0.344 0.00955 0.85 0.8294 0.9143 1258438 CBMicro_027734 NC(=O)CSc1nc2ccccc2n1CCOc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K17 compound treatment 0.418 0.0769 6.39 0.393 0.0585 5.19 8.1853 0.9947 1939533 CBMicro_027735 [O-][N+](=O)c1cc([N+](=O)[O-])c2cccnc2c1Sc3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K18 compound treatment 0.35 0.00894 0.74 0.348 0.0135 1.2 1.3736 0.9732 1678703 CBMicro_027736 Cc1nc2ccc(Cl)cc2c(c3ccccc3)c1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K19 compound treatment 0.34 -0.00106 -0.09 0.331 -0.00345 -0.31 -0.2788 -0.8756 1939534 CBMicro_027737 CC(Nc1ccc([N+](=O)[O-])c2cccnc12)C3(C[C@H]4C[C@@H]5C[C@H](C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K20 compound treatment 0.438 0.0969 8.05 0.43 0.0955 8.47 11.678 0.9997 1939535 CBMicro_027738 COc1ccc(cc1OC)C(=O)/C=C/c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K21 compound treatment 0.345 0.00394 0.33 0.341 0.00655 0.58 0.6414 0.9631 1939536 CBMicro_027739 Cc1cccc(C)c1NC(=O)CSCc2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K22 compound treatment 0.345 0.00394 0.33 0.339 0.00455 0.4 0.5161 0.9946 1474336 CBMicro_027740 Cc1cc(C)c2nc3sc(=Cc4ccccc4)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K23 positive control 0.086 -0.255 -21.18 0.086 -0.248 -22.02 -30.5424 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 K24 positive control 0.093 -0.248 -20.59 0.094 -0.24 -21.31 -29.6301 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L01 mock treatment 0.344 0.00294 0.24 0.335 5.48E-4 0.05 0.2067 0.8317 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L02 mock treatment 0.34 -0.00106 -0.09 0.333 -0.00145 -0.13 -0.1535 -0.9832 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L03 compound treatment 0.321 -0.0201 -1.67 0.309 -0.0255 -2.26 -2.7728 -0.9889 1939537 CBMicro_027741 C1CN2C(=CSC2=N1)c3ccc(cc3)C4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L04 compound treatment 0.316 -0.0251 -2.08 0.305 -0.0295 -2.61 -3.317 -0.9937 1939538 CBMicro_027742 [O-][N+](=O)c1cccc(Cl)c1C2NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L05 compound treatment 0.362 0.0209 1.74 0.362 0.0275 2.44 2.9553 0.9861 1939539 CBMicro_027743 Cc1ccc(cc1)C(=O)N/C(=C/c2ccc(Br)cc2)/C(=O)NCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L06 compound treatment 0.347 0.00594 0.49 0.341 0.00655 0.58 0.7588 0.9967 1939540 CBMicro_027744 COC(=O)c1ccc(/C=C\2/C=C(OC2=O)c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L07 compound treatment 0.345 0.00394 0.33 0.346 0.0115 1.02 0.9547 0.8887 1939541 CBMicro_027745 CC1CCN(CC1)c2ccc(/C=N/N=C/3\NC(=O)CS3)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L08 compound treatment 0.345 0.00394 0.33 0.356 0.0215 1.91 1.5814 0.8162 1939542 CBMicro_027746 COc1ccc(cc1)N2C(=O)/C(=C\C(=C\c3ccccc3)\Br)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L09 compound treatment 0.36 0.0189 1.57 0.353 0.0185 1.64 2.2739 0.9998 1939543 CBMicro_027747 COc1ccc(cc1)N(CC(=O)N/N=C/c2cccs2)S(=O)(=O)c3ccc(OC)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L10 compound treatment 0.378 0.0369 3.07 0.366 0.0315 2.8 4.1452 0.9989 1939544 CBMicro_027748 CN1CCN(CC1)C(=O)c2nn3c(cc(nc3c2Cl)c4ccccc4)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L11 compound treatment 0.358 0.0169 1.41 0.355 0.0205 1.82 2.2818 0.9918 1282148 CBMicro_027749 Brc1ccc(c2ccccc12)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L12 compound treatment 0.361 0.0199 1.66 0.35 0.0155 1.38 2.1446 0.9959 1939545 CBMicro_027750 CC1(C)Cc2ccccc2/C(=C(\C#N)/C(=O)Nc3ccccc3)/N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L13 compound treatment 0.335 -0.00606 -0.5 0.33 -0.00445 -0.39 -0.635 -0.9927 1677556 CBMicro_027751 Clc1ccc(cc1)S(=O)(=O)NCc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L14 compound treatment 0.339 -0.00206 -0.17 0.337 0.00255 0.23 0.0385 0.1358 1310802 CBMicro_027752 COC(=O)C1C(N(OC1(C)O)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L15 compound treatment 0.351 0.00994 0.82 0.34 0.00555 0.49 0.9309 0.9694 1472170 CBMicro_027753 Nc1ccc(cc1)c2nnc(o2)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L16 compound treatment 0.351 0.00994 0.82 0.348 0.0135 1.2 1.4323 0.9832 1491350 CBMicro_027754 Cc1cc(nc2cc(nn12)C(=O)N)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L17 compound treatment 0.349 0.00794 0.66 0.343 0.00855 0.76 1.0015 0.9976 1939546 CBMicro_027755 Cc1cc2nc3sc(=Cc4ccc(o4)c5ccc(Cl)cc5)c(=O)n3c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L18 compound treatment 0.338 -0.00306 -0.25 0.325 -0.00945 -0.84 -0.7722 -0.8821 1356973 CBMicro_027756 CCCn1c(SCc2nc3ccccc3[nH]2)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L19 compound treatment 0.398 0.0569 4.73 0.401 0.0665 5.9 7.5126 0.994 1939547 CBMicro_027757 CCOc1c(Br)cc(Br)cc1/C=C/2\SC(=S)NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L20 compound treatment 0.347 0.00594 0.49 0.34 0.00555 0.49 0.6961 1.0 1613502 CBMicro_027758 CC1=C(C(NC(=O)N1)c2ccc(Br)cc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L21 compound treatment 0.342 9.35E-4 0.08 0.338 0.00355 0.31 0.2773 0.856 1379521 CBMicro_027759 CC(=O)Nc1ccc2n(cnc2c1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L22 compound treatment 0.359 0.0179 1.49 0.34 0.00555 0.49 1.4006 0.8932 1851757 CBMicro_027760 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L23 positive control 0.087 -0.254 -21.09 0.086 -0.248 -22.02 -30.4837 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 L24 positive control 0.092 -0.249 -20.68 0.094 -0.24 -21.31 -29.6888 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M01 mock treatment 0.344 0.00294 0.24 0.335 5.48E-4 0.05 0.2067 0.8317 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M02 mock treatment 0.34 -0.00106 -0.09 0.333 -0.00145 -0.13 -0.1535 -0.9832 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M03 compound treatment 0.34 -0.00106 -0.09 0.334 -4.52E-4 -0.04 -0.0908 -0.9358 1670478 CBMicro_027761 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccc(Br)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M04 compound treatment 0.361 0.0199 1.66 0.347 0.0125 1.11 1.9566 0.9813 1472172 CBMicro_027762 Clc1ccc(C2NC(=O)c3sc(=S)n(c3N2)c4ccccc4)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M05 compound treatment 0.34 -0.00106 -0.09 0.339 0.00455 0.4 0.2225 0.5393 1939548 CBMicro_027763 CN1C(=O)N(C)C(=O)C(=CNCC2CCCO2)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M06 compound treatment 0.358 0.0169 1.41 0.352 0.0175 1.56 2.0938 0.9987 1166001 CBMicro_027764 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4ccc(cc4)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M07 compound treatment 0.339 -0.00206 -0.17 0.332 -0.00245 -0.22 -0.2748 -0.9931 1779943 CBMicro_027765 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(c3)[N+](=O)[O-])c(=O)n2C1c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M08 compound treatment 0.342 9.35E-4 0.08 0.33 -0.00445 -0.39 -0.224 -0.5572 1939549 CBMicro_027766 C/C(=C\C(=O)ONC(=O)c1ccccc1)/NCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M09 compound treatment 0.359 0.0179 1.49 0.35 0.0155 1.38 2.0272 0.9993 1939550 CBMicro_027767 COCCCN1C(=C(C(=O)OC)/C(=C/c2ccc(OCC=C)c(OC)c2)/C1=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M10 compound treatment 0.335 -0.00606 -0.5 0.331 -0.00345 -0.31 -0.5723 -0.9715 1776213 CBMicro_027768 Cc1nn(CC(=O)NCCN2CCOCC2)c(C)c1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M11 compound treatment 0.349 0.00794 0.66 0.347 0.0125 1.11 1.2522 0.9688 1939551 CBMicro_027769 Oc1ccccc1/C=N/NC(=O)C(=O)N2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M12 compound treatment 0.351 0.00994 0.82 0.348 0.0135 1.2 1.4323 0.9832 1939552 CBMicro_027770 CC(=O)Oc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)NCC(=O)OCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M13 compound treatment 0.352 0.0109 0.91 0.358 0.0235 2.09 2.1176 0.9305 1481035 CBMicro_027771 COc1ccc(NC(=O)Nc2ccc(Cc3ccncc3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M14 compound treatment 0.344 0.00294 0.24 0.342 0.00755 0.67 0.6453 0.9064 1939553 CBMicro_027772 COCCCNC(=O)CC(=O)N/N=C/c1cc(OC)c(OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M15 compound treatment 0.346 0.00494 0.41 0.341 0.00655 0.58 0.7001 0.9855 1275465 CBMicro_027773 CCCC1=C(C(NC(=O)N1)c2ccc(OC)c(OC)c2)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M16 compound treatment 0.343 0.00194 0.16 0.345 0.0105 0.93 0.7746 0.8167 1583488 CBMicro_027774 COc1cc2CC(C)(C)n3c(nnc3-c2cc1OC)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M17 compound treatment 0.342 9.35E-4 0.08 0.335 5.48E-4 0.05 0.0893 0.9745 1528779 CBMicro_027775 Cc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M18 compound treatment 0.465 0.124 10.29 0.411 0.0765 6.78 12.0723 0.9796 1939554 CBMicro_027776 CN(/N=C/c1ccc(cc1)[N+](=O)[O-])C(=S)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M19 compound treatment 0.334 -0.00706 -0.59 0.33 -0.00445 -0.39 -0.6937 -0.9814 1939555 CBMicro_027777 CC(C)c1ccc(cc1)C2NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M20 compound treatment 0.347 0.00594 0.49 0.338 0.00355 0.31 0.5708 0.9765 1439116 CBMicro_027778 CC1(C)Cc2ccccc2-c3nnc(c4cccnc4)n31 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M21 compound treatment 0.337 -0.00406 -0.34 0.33 -0.00445 -0.39 -0.5176 -0.997 1939556 CBMicro_027779 [O-][N+](=O)c1cc2OCOc2cc1C3NN=C(S3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M22 compound treatment 0.346 0.00494 0.41 0.343 0.00855 0.76 0.8254 0.9584 1384167 CBMicro_027780 CCOC(=O)N1CCc2c(C(=O)OCC)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M23 positive control 0.088 -0.253 -21.01 0.089 -0.245 -21.75 -30.237 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 M24 positive control 0.094 -0.247 -20.51 0.095 -0.239 -21.22 -29.5088 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N01 mock treatment 0.349 0.00794 0.66 0.339 0.00455 0.4 0.7509 0.9722 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N02 mock treatment 0.348 0.00694 0.58 0.341 0.00655 0.58 0.8175 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N03 compound treatment 0.357 0.0159 1.32 0.346 0.0115 1.02 1.6591 0.992 1939557 CBMicro_027781 Fc1cccc(NC(=S)NC(=O)c2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N04 compound treatment 0.371 0.0299 2.49 0.369 0.0345 3.06 3.9223 0.9946 1939558 CBMicro_027782 CCNC(=S)NNC(=O)CCn1c2ccccc2c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N05 compound treatment 0.348 0.00694 0.58 0.342 0.00755 0.67 0.8802 0.9972 1228856 CBMicro_027783 Cc1ccc(cc1)C(=O)CSc2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N06 compound treatment 0.391 0.0499 4.15 0.382 0.0475 4.21 5.911 1.0 1939559 CBMicro_027784 CC(C)(C)c1cc(C=C2C(=O)NC(=S)NC2=O)cc(c1O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N07 compound treatment 0.344 0.00294 0.24 0.344 0.00955 0.85 0.7707 0.8752 1939560 CBMicro_027785 CCOC(=O)C(CCc1nnc(N)s1)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N08 compound treatment 0.355 0.0139 1.16 0.351 0.0165 1.47 1.8551 0.9931 1939561 CBMicro_027786 COc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N09 compound treatment 0.345 0.00394 0.33 0.338 0.00355 0.31 0.4534 0.9998 1548306 CBMicro_027787 Cc1ccc2c(nc3sc(=Cc4ccc(Cl)cc4Cl)c(=O)n32)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N10 compound treatment 0.391 0.0499 4.15 0.392 0.0575 5.1 6.5377 0.9947 1939562 CBMicro_027788 COc1ccc(/C=C\2/C=C(OC2=O)c3ccc(C)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N11 compound treatment 0.36 0.0189 1.57 0.361 0.0265 2.35 2.7752 0.9808 1574996 CBMicro_027789 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(OC)c(OC)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N12 compound treatment 0.872 0.531 44.08 0.868 0.534 47.28 64.6025 0.9994 1939563 CBMicro_027790 Cc1cc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccs3)cc2)nc(C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N13 compound treatment 0.353 0.0119 0.99 0.349 0.0145 1.29 1.6123 0.9915 1939564 CBMicro_027791 Cc1cc(C)c2nc3sc(=Cc4ccc(o4)c5cccc(Cl)c5)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N14 compound treatment 0.42 0.0789 6.55 0.416 0.0815 7.23 9.744 0.9988 1939565 CBMicro_027792 Clc1ccc(/C=C(/NC(=O)c2ccccc2)\c3nc4ccccc4[nH]3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N15 compound treatment 0.347 0.00594 0.49 0.341 0.00655 0.58 0.7588 0.9967 1939566 CBMicro_027793 CCOC(=O)C1CCN(CC1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N16 compound treatment 0.359 0.0179 1.49 0.35 0.0155 1.38 2.0272 0.9993 1939567 CBMicro_027794 Clc1ccc(cc1)C2NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N17 compound treatment 0.381 0.0399 3.32 0.372 0.0375 3.33 4.6973 1.0 1939568 CBMicro_027795 O/N=C/C(=N/NC(=O)c1cccc(Br)c1)/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N18 compound treatment 0.428 0.0869 7.22 0.404 0.0695 6.16 9.4617 0.9969 1939569 CBMicro_027796 CCOC(=O)/C(=C/1\NC(C)(C)Cc2ccccc12)/C(=O)Nc3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N19 compound treatment 0.347 0.00594 0.49 0.336 0.00155 0.14 0.4455 0.8709 1780066 CBMicro_027797 CCc1sc(cc1[N+](=O)[O-])c2c(C#N)c(N)nc3CCCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N20 compound treatment 0.349 0.00794 0.66 0.334 -4.52E-4 -0.04 0.4375 0.6629 1778821 CBMicro_027798 [O-][N+](=O)c1ncn(CC(=O)Nc2cc(Sc3ccc(Br)cc3)cc(c2)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N21 compound treatment 0.354 0.0129 1.07 0.35 0.0155 1.38 1.7337 0.9924 1939570 CBMicro_027799 Clc1ccc(cc1Cl)N2C(=O)CC(N3CCN(C/C=C/c4ccccc4)CC3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N22 compound treatment 0.345 0.00394 0.33 0.342 0.00755 0.67 0.704 0.9457 1939571 CBMicro_027800 CCOC(=O)c1c(NC(=O)CN2CCN(C)CC2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N23 positive control 0.088 -0.253 -21.01 0.088 -0.246 -21.84 -30.2996 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 N24 positive control 0.091 -0.25 -20.76 0.093 -0.241 -21.4 -29.8102 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O01 mock treatment 0.349 0.00794 0.66 0.342 0.00755 0.67 0.9389 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O02 mock treatment 0.345 0.00394 0.33 0.338 0.00355 0.31 0.4534 0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O03 compound treatment 0.346 0.00494 0.41 0.338 0.00355 0.31 0.5121 0.9915 1939572 CBMicro_027801 Fc1ccccc1/C=C(/NC(=O)c2ccccc2)\C(=O)NCC(=O)OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O04 compound treatment 0.349 0.00794 0.66 0.342 0.00755 0.67 0.9389 1.0 1939573 CBMicro_027802 COc1cc(NC(=O)Cn2nc(c(Br)c2C)C(F)(F)F)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O05 compound treatment 0.337 -0.00406 -0.34 0.328 -0.00645 -0.57 -0.6429 -0.9684 1939574 CBMicro_027803 CN1/C(=C\C(=O)Nc2ccc(Cl)cc2)/c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O06 compound treatment 0.348 0.00694 0.58 0.342 0.00755 0.67 0.8802 0.9972 1939575 CBMicro_027804 O=C(NCc1ccc2OCOc2c1)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O07 compound treatment 0.341 -6.45E-5 -0.01 0.332 -0.00245 -0.22 -0.1574 -0.7243 1939576 CBMicro_027805 CC1=C(C(NC(=S)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O08 compound treatment 0.385 0.0439 3.65 0.39 0.0555 4.92 6.0601 0.9891 1712399 CBMicro_027806 COc1ccc(cc1)c2nc(NC(=O)c3ccco3)sc2c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O09 compound treatment 0.354 0.0129 1.07 0.349 0.0145 1.29 1.671 0.9959 1939577 CBMicro_027807 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3nn4c(cc(nc4c3Br)c5cccs5)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O10 compound treatment 0.342 9.35E-4 0.08 0.331 -0.00345 -0.31 -0.1614 -0.5114 1392959 CBMicro_027808 CN(C)CCCN1C(SCC1=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O11 compound treatment 0.349 0.00794 0.66 0.34 0.00555 0.49 0.8135 0.9896 1275169 CBMicro_027809 CN(C)c1ccc(C=c2sc3nc4c(C)cc(C)cc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O12 compound treatment 0.353 0.0119 0.99 0.35 0.0155 1.38 1.675 0.9869 1939578 CBMicro_027810 CC(=O)NN1C(=O)/C(=C/2\C(=O)Nc3ccc(C)cc23)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O13 compound treatment 0.344 0.00294 0.24 0.34 0.00555 0.49 0.52 0.9476 1939579 CBMicro_027811 CC(=O)NC1=NN(C(=O)C)C(C)(S1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O14 compound treatment 0.344 0.00294 0.24 0.34 0.00555 0.49 0.52 0.9476 1939580 CBMicro_027812 Cc1c(Cl)c(nn1CC(=O)NCCCn2ccnc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O15 compound treatment 0.366 0.0249 2.07 0.346 0.0115 1.02 2.1875 0.9473 1939581 CBMicro_027813 CCOC(=O)/C(=C/1\NC(C)(C)Cc2ccccc12)/C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O16 compound treatment 0.326 -0.0151 -1.25 0.32 -0.0145 -1.28 -1.7899 -0.9999 1939582 CBMicro_027814 Clc1cccc(CSCCNC(=O)/C=C/c2ccc3OCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O17 compound treatment 0.276 -0.0651 -5.4 0.26 -0.0745 -6.6 -8.485 -0.9951 1939583 CBMicro_027815 O=C/1N(C2CCCCC2)C(=S)S\C1=C\c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O18 compound treatment 0.35 0.00894 0.74 0.346 0.0115 1.02 1.2482 0.9875 1939584 CBMicro_027816 OCCCNC(=O)/C(=C/c1ccc2OCOc2c1)/NC(=O)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O19 compound treatment 0.362 0.0209 1.74 0.351 0.0165 1.47 2.266 0.9964 1722477 CBMicro_027817 Nc1sc2CCCc2c1C(=O)Nc3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O20 compound treatment 0.367 0.0259 2.15 0.362 0.0275 2.44 3.2488 0.998 1939585 CBMicro_027818 COc1cccc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O21 compound treatment 0.337 -0.00406 -0.34 0.33 -0.00445 -0.39 -0.5176 -0.997 1519141 CBMicro_027819 CN1C(CC(=O)Nc2ccc(Br)cc2)c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O22 compound treatment 0.349 0.00794 0.66 0.343 0.00855 0.76 1.0015 0.9976 1157314 CBMicro_027820 COc1ccccc1c2nnc(NC(=O)c3ccc(F)cc3)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O23 positive control 0.087 -0.254 -21.09 0.087 -0.247 -21.93 -30.421 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 O24 positive control 0.092 -0.249 -20.68 0.092 -0.242 -21.49 -29.8142 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P01 mock treatment 0.341 -6.45E-5 -0.01 0.338 0.00355 0.31 0.2186 0.695 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P02 mock treatment 0.345 0.00394 0.33 0.34 0.00555 0.49 0.5787 0.9803 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P03 compound treatment 0.346 0.00494 0.41 0.341 0.00655 0.58 0.7001 0.9855 1939586 CBMicro_027821 [O-][N+](=O)c1ccccc1/C=C/2\SC(=S)N(C2=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P04 compound treatment 0.347 0.00594 0.49 0.337 0.00255 0.23 0.5081 0.9374 1939587 CBMicro_027822 Cc1ccc(COc2c(Br)cc(/C=C(\C#N)/c3nn(c(N)c3C#N)c4ccccc4)cc2Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P05 compound treatment 0.356 0.0149 1.24 0.351 0.0165 1.47 1.9138 0.9965 1939588 CBMicro_027823 COc1cc(C(c2ccc(C)o2)c3ccc(C)o3)c(O)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P06 compound treatment 0.353 0.0119 0.99 0.345 0.0105 0.93 1.3617 0.9996 1541600 CBMicro_027824 COc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccc(C)cc3)c4cc(C)ccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P07 compound treatment 0.305 -0.0361 -2.99 0.321 -0.0135 -1.19 -2.9601 -0.9185 1163343 CBMicro_027825 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc6OCOc6c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P08 compound treatment 0.364 0.0229 1.9 0.35 0.0155 1.38 2.3207 0.9874 1939589 CBMicro_027826 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P09 compound treatment 0.348 0.00694 0.58 0.341 0.00655 0.58 0.8175 1.0 1939590 CBMicro_027827 Cc1ccc(Nc2nc(cs2)c3cccs3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P10 compound treatment 0.369 0.0279 2.32 0.359 0.0245 2.18 3.1782 0.9995 1939591 CBMicro_027828 CC1(C)Cc2ccccc2/C(=C/C(=O)Nc3ccc(cc3)[N+](=O)[O-])/N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P11 compound treatment 0.348 0.00694 0.58 0.338 0.00355 0.31 0.6295 0.9595 1939592 CBMicro_027829 O=C(CN1CCCCC1)OCC2CCCO2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P12 compound treatment 0.339 -0.00206 -0.17 0.333 -0.00145 -0.13 -0.2122 -0.99 1939593 CBMicro_027830 Cc1c(Br)c(nn1CC(=O)Nc2cccc(O)c2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P13 compound treatment 0.35 0.00894 0.74 0.343 0.00855 0.76 1.0602 0.9999 1939594 CBMicro_027831 Cc1sc(cc1[N+](=O)[O-])C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P14 compound treatment 0.361 0.0199 1.66 0.359 0.0245 2.18 2.7086 0.9909 1939595 CBMicro_027832 CSCCC(NC(=O)c1cc(COc2ccc(cc2)c3ccccc3)c(C)o1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P15 compound treatment 0.324 -0.0171 -1.42 0.307 -0.0275 -2.43 -2.722 -0.9669 1939596 CBMicro_027833 CN(C)c1ccc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P16 compound treatment 0.366 0.0249 2.07 0.363 0.0285 2.53 3.2528 0.995 1939597 CBMicro_027834 Oc1ccc2ccccc2c1C3NN=C(S3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P17 compound treatment 0.367 0.0259 2.15 0.339 0.00455 0.4 1.8075 0.8251 1698978 CBMicro_027835 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P18 compound treatment 0.352 0.0109 0.91 0.348 0.0135 1.2 1.491 0.9905 1939598 CBMicro_027836 CN1C(=O)C2(NN=C(S2)c3ccccc3)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P19 compound treatment 0.351 0.00994 0.82 0.339 0.00455 0.4 0.8683 0.9458 1939599 CBMicro_027837 [O-][N+](=O)c1cccc(/C=C/C(=O)Nc2ccc(cc2)N3CCCCC3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P20 compound treatment 0.352 0.0109 0.91 0.35 0.0155 1.38 1.6163 0.9795 1939600 CBMicro_027838 C1CC(=NN1c2ccccc2)/N=C/N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P21 compound treatment 0.35 0.00894 0.74 0.336 0.00155 0.14 0.6216 0.8239 1939601 CBMicro_027839 COC(=O)Cn1c2/C(=N/Cc3ccccc3)/CCCc2c4cc(C)ccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P22 compound treatment 0.359 0.0179 1.49 0.364 0.0295 2.62 2.9045 0.9642 1939602 CBMicro_027840 COc1cc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)cc(Br)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P23 positive control 0.091 -0.25 -20.76 0.093 -0.241 -21.4 -29.8102 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.772 P24 positive control 0.091 -0.25 -20.76 0.093 -0.241 -21.4 -29.8102 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A01 mock treatment 0.321 -0.012 -1.0 0.322 -0.0131 -1.16 -1.5272 -0.997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A02 mock treatment 0.33 -0.003 -0.25 0.329 -0.00613 -0.54 -0.5602 -0.9375 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A03 compound treatment 0.326 -0.007 -0.58 0.322 -0.0131 -1.16 -1.2337 -0.9485 1644715 CBMicro_027841 Cn1c(=O)c(C(=O)NC2CCCC2)c(O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A04 compound treatment 0.33 -0.003 -0.25 0.326 -0.00913 -0.81 -0.7482 -0.8839 1939603 CBMicro_027842 CCc1cccc(C)c1NC(=O)CSc2nnnn2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A05 compound treatment 0.329 -0.004 -0.33 0.332 -0.00313 -0.28 -0.4309 -0.996 1430468 CBMicro_027843 Clc1ccccc1C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A06 compound treatment 0.354 0.021 1.74 0.355 0.0199 1.76 2.478 1.0 1939604 CBMicro_027844 COc1ccc(O)c(c1)C2NN=C(Cc3ccccc3)S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A07 compound treatment 0.374 0.041 3.4 0.366 0.0309 2.74 4.3414 0.9941 1939605 CBMicro_027845 Cc1sc(/C=C(/C#N)\C(=S)N)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A08 compound treatment 0.327 -0.006 -0.5 0.336 8.71E-4 0.08 -0.2976 -0.5905 1462940 CBMicro_027846 Cc1cc(nc(n1)c2ccccc2O)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A09 compound treatment 0.326 -0.007 -0.58 0.328 -0.00713 -0.63 -0.8577 -0.9991 1939606 CBMicro_027847 CCCn1c(/N=C/c2cccc(CC=C)c2O)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A10 compound treatment 0.301 -0.032 -2.66 0.311 -0.0241 -2.14 -3.3906 -0.9942 1939607 CBMicro_027848 CC1=C(C(NC(=S)N1)c2cccc3ccccc23)C(=O)Nc4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A11 compound treatment 0.334 0.001 0.08 0.337 0.00187 0.17 0.1759 0.9489 1939608 CBMicro_027849 CC12CCCCC2C1C(=O)N/N=C\c3ccc(o3)c4ccc(cc4)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A12 compound treatment 0.327 -0.006 -0.5 0.324 -0.0111 -0.99 -1.0496 -0.9499 1445174 CBMicro_027850 COC(=O)C1=NN(C(=O)c2cccc(OC)c2)C(C)(O)C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A13 compound treatment 0.324 -0.009 -0.75 0.331 -0.00413 -0.37 -0.7871 -0.946 1939609 CBMicro_027851 COc1cc(/C=N/NC(=O)C(=O)N2CCCCCC2)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A14 compound treatment 0.337 0.004 0.33 0.337 0.00187 0.17 0.3521 0.9485 1939610 CBMicro_027852 CCCCSc1nnc-2c(OC(Nc3ccccc32)/C=C/c4ccc(o4)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A15 compound treatment 0.326 -0.007 -0.58 0.327 -0.00813 -0.72 -0.9203 -0.9943 1939611 CBMicro_027853 NC(=O)C(Cc1ccccc1)N2CC(=O)NC(=O)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A16 compound treatment 0.345 0.012 1.0 0.338 0.00287 0.25 0.8843 0.8601 1545868 CBMicro_027854 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2C)c3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A17 compound treatment 0.351 0.018 1.49 0.351 0.0159 1.41 2.0512 0.9995 1358654 CBMicro_027855 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(C)cc3)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A18 compound treatment 0.333 0.0 0.0 0.332 -0.00313 -0.28 -0.1961 -0.7071 1939612 CBMicro_027856 COc1ccc(cc1)C2NN=C(Cc3ccccc3)S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A19 compound treatment 0.336 0.003 0.25 0.333 -0.00213 -0.19 0.0427 0.1366 1939613 CBMicro_027857 Cc1ccc(NC(=O)/C(=C\c2cccnc2)/NC(=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A20 compound treatment 0.322 -0.011 -0.91 0.322 -0.0131 -1.16 -1.4685 -0.9928 1138141 CBMicro_027858 COc1ccccc1OCC(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A21 compound treatment 0.321 -0.012 -1.0 0.326 -0.00913 -0.81 -1.2765 -0.9947 1579819 CBMicro_027859 Nc1nnc(s1)c2ccccc2c3nnc(N)s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A22 compound treatment 0.327 -0.006 -0.5 0.327 -0.00813 -0.72 -0.8616 -0.9838 1939614 CBMicro_027860 COc1cccc2c(Cl)c(CC=C(Cl)Cl)c(C)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A23 positive control 0.082 -0.251 -20.84 0.083 -0.252 -22.34 -30.5342 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 A24 positive control 0.083 -0.25 -20.75 0.084 -0.251 -22.26 -30.4128 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B01 mock treatment 0.332 -0.001 -0.08 0.33 -0.00513 -0.45 -0.3801 -0.8226 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B02 mock treatment 0.335 0.002 0.17 0.343 0.00787 0.7 0.6106 0.8516 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B03 compound treatment 0.335 0.002 0.17 0.333 -0.00213 -0.19 -0.016 -0.0637 1578137 CBMicro_027861 Cc1cc(C)cc(NC(=O)c2cc(nc3ccccc23)c4cccs4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B04 compound treatment 0.344 0.011 0.91 0.34 0.00487 0.43 0.951 0.9415 1939615 CBMicro_027862 CCN(CC)c1nc(C)cc(COC)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B05 compound treatment 0.32 -0.013 -1.08 0.322 -0.0131 -1.16 -1.5859 -0.9993 1939616 CBMicro_027863 CCCCCCCc1ccc(nc1)c2ccc(O)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B06 compound treatment 0.39 0.057 4.73 0.39 0.0549 4.86 6.7846 0.9999 1928605 CBMicro_027864 COCC(O)CN1CCN(CC1)c2ccc(cc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B07 compound treatment 0.337 0.004 0.33 0.342 0.00687 0.61 0.6654 0.9593 1310022 CBMicro_027865 COc1ccc(OCC(=O)Nc2ccc(OC)cc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B08 compound treatment 0.345 0.012 1.0 0.346 0.0109 0.96 1.3857 0.9999 1156305 CBMicro_027866 CC1=CC(C)(C)Nc2ccc(OC(=O)Cc3cccc4ccccc34)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B09 compound treatment 0.328 -0.005 -0.42 0.331 -0.00413 -0.37 -0.5523 -0.998 1939617 CBMicro_027867 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B10 compound treatment 0.343 0.01 0.83 0.324 -0.0111 -0.99 -0.1104 -0.0856 1667411 CBMicro_027868 Cc1cccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc4CCCc24)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B11 compound treatment 0.335 0.002 0.17 0.333 -0.00213 -0.19 -0.016 -0.0637 1939618 CBMicro_027869 CC(=O)CCc1c(C)nc2ccc(Br)cc2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B12 compound treatment 0.327 -0.006 -0.5 0.334 -0.00113 -0.1 -0.423 -0.8325 1939619 CBMicro_027870 OC(C(=O)NCCCCOc1ccccc1)(c2ccc(Cl)cc2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B13 compound treatment 0.327 -0.006 -0.5 0.312 -0.0231 -2.05 -1.8016 -0.8541 1939620 CBMicro_027871 Fc1ccccc1c2nc(no2)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B14 compound treatment 0.381 0.048 3.98 0.365 0.0299 2.65 4.6896 0.9803 1939621 CBMicro_027872 CCN(CC)c1ccc(/C=N/NC(=O)Cn2nnc(n2)c3ccccc3)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B15 compound treatment 0.339 0.006 0.5 0.339 0.00387 0.34 0.5948 0.9834 1939622 CBMicro_027873 Clc1ccc(OCCCC(=O)Nc2ccc3C(=O)OCc3c2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B16 compound treatment 0.341 0.008 0.66 0.342 0.00687 0.61 0.9002 0.9991 1939623 CBMicro_027874 CSCCC(NC1=NC(C)(C)Cc2c1ccc3ccccc23)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B17 compound treatment 0.337 0.004 0.33 0.333 -0.00213 -0.19 0.1014 0.2655 1939624 CBMicro_027875 COc1cc(cc(OC)c1OC)C(=O)N/N=C/c2ccc(C)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B18 compound treatment 0.338 0.005 0.42 0.34 0.00487 0.43 0.5988 0.9998 1582631 CBMicro_027876 O=C1N(Cc2ccccc2)c3ccccc3C1=c4sc5nc6ccccc6n5c4=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B19 compound treatment 0.328 -0.005 -0.42 0.327 -0.00813 -0.72 -0.8029 -0.9657 1939625 CBMicro_027877 CC(N)C(=O)c1c(C)cc(C)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B20 compound treatment 0.184 -0.149 -12.37 0.199 -0.136 -12.06 -17.2773 -0.9999 1533387 CBMicro_027878 CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc3CN(Cc4ccccc4)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B21 compound treatment 0.338 0.005 0.42 0.339 0.00387 0.34 0.5361 0.9955 1608221 CBMicro_027879 CCOc1cccc(c1)C(=O)Nc2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B22 compound treatment 0.333 0.0 0.0 0.335 -1.29E-4 -0.01 -0.0081 -0.7071 1479237 CBMicro_027880 CC1(C)CNC(=O)c2sc(N)nc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B23 positive control 0.081 -0.252 -20.92 0.084 -0.251 -22.26 -30.5303 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 B24 positive control 0.083 -0.25 -20.75 0.087 -0.248 -21.99 -30.2249 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C01 mock treatment 0.339 0.006 0.5 0.339 0.00387 0.34 0.5948 0.9834 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C02 mock treatment 0.343 0.01 0.83 0.351 0.0159 1.41 1.5816 0.9684 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C03 compound treatment 0.325 -0.008 -0.66 0.334 -0.00113 -0.1 -0.5404 -0.8046 1779823 CBMicro_027881 Cc1cc2nc3sc(=Cc4ccc(cc4)[N+](=O)[O-])c(=O)n3c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C04 compound treatment 0.353 0.02 1.66 0.352 0.0169 1.5 2.2313 0.9986 1147646 CBMicro_027882 Cc1ccc(NC(=O)c2[nH]cnc2C(=O)N3CCCCC3)c(c1)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C05 compound treatment 0.354 0.021 1.74 0.353 0.0179 1.58 2.3527 0.9989 1743142 CBMicro_027883 COc1ccccc1C(=O)Nc2nnc(s2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C06 compound treatment 0.489 0.156 12.95 0.509 0.174 15.41 20.0534 0.9963 1939626 CBMicro_027884 Oc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C07 compound treatment 0.345 0.012 1.0 0.345 0.00987 0.87 1.323 0.9979 1939627 CBMicro_027885 CC1CN(CC(C)N1/C(=N\O)/c2nonc2N)c3ccc(cc3Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C08 compound treatment 0.512 0.179 14.86 0.504 0.169 14.97 21.0902 1.0 1939628 CBMicro_027886 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)cc([N+](=O)[O-])c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C09 compound treatment 0.46 0.127 10.54 0.454 0.119 10.53 14.9044 1.0 1939629 CBMicro_027887 NCCNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C10 compound treatment 0.354 0.021 1.74 0.351 0.0159 1.41 2.2273 0.9943 1939630 CBMicro_027888 Fc1ccc(NC(=O)C(=O)N/N=C/c2ccc3OCCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C11 compound treatment 0.374 0.041 3.4 0.374 0.0389 3.44 4.8427 1.0 1440925 CBMicro_027889 CCOc1ccc(cc1)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C12 compound treatment 0.344 0.011 0.91 0.348 0.0129 1.14 1.4523 0.9939 1939631 CBMicro_027890 CC1(C)CC2(CCO1)NN=C(S2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C13 compound treatment 0.377 0.044 3.65 0.367 0.0319 2.82 4.5801 0.9919 1939632 CBMicro_027891 COc1cccc(/C=C/2\SC(=S)N(C2=O)c3cccc(F)c3)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C14 compound treatment 0.386 0.053 4.4 0.385 0.0499 4.42 6.2364 1.0 1939633 CBMicro_027892 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)NCCCN3CCOCC3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C15 compound treatment 0.347 0.014 1.16 0.349 0.0139 1.23 1.6911 0.9996 1939634 CBMicro_027893 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4c[nH]nc4c5ccccc5)C(=O)CC(C)(C)C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C16 compound treatment 0.341 0.008 0.66 0.342 0.00687 0.61 0.9002 0.9991 1939635 CBMicro_027894 C/C(=N\NC(=O)C1(CC2CC3CC(C2)C1)C3)/CC(=O)NCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C17 compound treatment 0.341 0.008 0.66 0.343 0.00787 0.7 0.9629 0.9997 1939636 CBMicro_027895 Clc1ccc(Cc2noc(n2)c3cccs3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C18 compound treatment 0.36 0.027 2.24 0.356 0.0209 1.85 2.8929 0.9954 1939637 CBMicro_027896 CCOC(=O)c1cc2nc(cc(C)n2n1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C19 compound treatment 0.35 0.017 1.41 0.341 0.00587 0.52 1.3659 0.908 1939638 CBMicro_027897 CCCCc1sc(cc1[N+](=O)[O-])c2c(C#N)c(N)nc3CCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C20 compound treatment 0.348 0.015 1.25 0.346 0.0109 0.96 1.5618 0.992 1939639 CBMicro_027898 COc1ccc(cc1OC)C(=O)NNC(=O)c2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C21 compound treatment 0.351 0.018 1.49 0.354 0.0189 1.67 2.2392 0.9984 1939640 CBMicro_027899 Clc1ccccc1c2ccc(o2)C(=S)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C22 compound treatment 0.345 0.012 1.0 0.345 0.00987 0.87 1.323 0.9979 1493218 CBMicro_027900 COc1cccc(OCC(=O)Nc2ccc(OC)c(OC)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C23 positive control 0.083 -0.25 -20.75 0.083 -0.252 -22.34 -30.4755 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 C24 positive control 0.088 -0.245 -20.34 0.086 -0.249 -22.08 -29.994 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D01 mock treatment 0.333 0.0 0.0 0.335 -1.29E-4 -0.01 -0.0081 -0.7071 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D02 mock treatment 0.342 0.009 0.75 0.342 0.00687 0.61 0.9589 0.9948 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D03 compound treatment 0.343 0.01 0.83 0.34 0.00487 0.43 0.8923 0.9536 1448478 CBMicro_027901 COc1ccc(CNC(=O)COc2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D04 compound treatment 0.329 -0.004 -0.33 0.331 -0.00413 -0.37 -0.4936 -0.9988 1521079 CBMicro_027902 CCCC1=C(C(NC(=O)N1)c2ccc(CC)cc2)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D05 compound treatment 0.334 0.001 0.08 0.329 -0.00613 -0.54 -0.3254 -0.5922 1694708 CBMicro_027903 O=C(CCc1ccccc1)Nc2nc(cs2)c3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D06 compound treatment 0.34 0.007 0.58 0.339 0.00387 0.34 0.6535 0.9684 1720905 CBMicro_027904 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(F)c(F)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D07 compound treatment 0.337 0.004 0.33 0.341 0.00587 0.52 0.6027 0.9765 1939641 CBMicro_027905 [O-][N+](=O)c1ccc2[nH]c(SCC(=O)c3ccc(F)cc3)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D08 compound treatment 0.345 0.012 1.0 0.349 0.0139 1.23 1.5737 0.9946 1257729 CBMicro_027906 COc1ccccc1NC(=O)c2c(NC(=O)Cc3ccccc3)sc4CCCc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D09 compound treatment 0.339 0.006 0.5 0.338 0.00287 0.25 0.5321 0.9514 1494057 CBMicro_027907 COc1ccccc1OCC(=O)NCc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D10 compound treatment 0.361 0.028 2.32 0.35 0.0149 1.32 2.5756 0.9639 1513770 CBMicro_027908 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC)c(=O)n2C1c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D11 compound treatment 0.356 0.023 1.91 0.366 0.0309 2.74 3.2847 0.9845 1939642 CBMicro_027909 CCCc1c(C)nc2ccc(OC)cc2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D12 compound treatment 0.333 0.0 0.0 0.336 8.71E-4 0.08 0.0546 0.7071 1939643 CBMicro_027910 CN(C)c1ccc(cc1)C2NC(=S)NC(=C2C(=O)Nc3ccc(Cl)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D13 compound treatment 0.334 0.001 0.08 0.337 0.00187 0.17 0.1759 0.9489 1392513 CBMicro_027911 COc1ccc(OCC(=O)Nc2ccccc2CO)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D14 compound treatment 0.328 -0.005 -0.42 0.343 0.00787 0.7 0.1997 0.246 1939644 CBMicro_027912 Clc1ccccc1Cn2cc(/C=C/3\Sc4ccccc4C3=O)c5ccccc25 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D15 compound treatment 0.332 -0.001 -0.08 0.335 -1.29E-4 -0.01 -0.0668 -0.797 1939645 CBMicro_027913 CCCN1CCC(=NNC(=O)c2c[nH]c3ccccc23)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D16 compound treatment 0.335 0.002 0.17 0.338 0.00287 0.25 0.2973 0.9786 1405419 CBMicro_027914 Fc1cnc(nc1N2CCOCC2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D17 compound treatment 0.343 0.01 0.83 0.342 0.00687 0.61 1.0176 0.9884 1404931 CBMicro_027915 COc1ccc(NC(=O)COc2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D18 compound treatment 0.39 0.057 4.73 0.38 0.0449 3.98 6.1579 0.9963 1355280 CBMicro_027916 CC1(C)CC(=O)C(=C2C=C(OC(=C2)c3ccccc3)c4ccccc4)C(=O)C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D19 compound treatment 0.336 0.003 0.25 0.336 8.71E-4 0.08 0.2307 0.8847 1939646 CBMicro_027917 CCCN1CCC(=NNC(=O)c2cccc3ccccc23)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D20 compound treatment 0.34 0.007 0.58 0.34 0.00487 0.43 0.7162 0.9893 1257707 CBMicro_027918 CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D21 compound treatment 0.349 0.016 1.33 0.348 0.0129 1.14 1.7458 0.9971 1939647 CBMicro_027919 [O-][N+](=O)c1cccc(c1)C(=O)N2CCN(CC2)c3cccc(c3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D22 compound treatment 0.268 -0.065 -5.4 0.268 -0.0671 -5.95 -8.0224 -0.9988 1939648 CBMicro_027920 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D23 positive control 0.081 -0.252 -20.92 0.083 -0.252 -22.34 -30.5929 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 D24 positive control 0.085 -0.248 -20.59 0.087 -0.248 -21.99 -30.1074 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E01 mock treatment 0.326 -0.007 -0.58 0.327 -0.00813 -0.72 -0.9203 -0.9943 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E02 mock treatment 0.338 0.005 0.42 0.339 0.00387 0.34 0.5361 0.9955 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E03 compound treatment 0.341 0.008 0.66 0.341 0.00587 0.52 0.8375 0.9927 1939649 CBMicro_027921 [O-][N+](=O)c1ccccc1C(=O)NN2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E04 compound treatment 0.339 0.006 0.5 0.34 0.00487 0.43 0.6575 0.9975 1939650 CBMicro_027922 Clc1ccc(cc1)C(=O)COC(=O)CSc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E05 compound treatment 0.332 -0.001 -0.08 0.335 -1.29E-4 -0.01 -0.0668 -0.797 1939651 CBMicro_027923 O=C/1ON=C(\C1=C\c2cccnc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E06 compound treatment 0.332 -0.001 -0.08 0.33 -0.00513 -0.45 -0.3801 -0.8226 1939652 CBMicro_027924 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)/N=C/2\S/C(=C/3\C(=O)Nc4ccccc34)/C(=O)N2CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E07 compound treatment 0.405 0.072 5.98 0.422 0.0869 7.7 9.6704 0.9922 1939653 CBMicro_027925 Cc1cc(Nc2ccc(cc2)[N+](=O)[O-])nc(n1)c3ccccc3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E08 compound treatment 0.357 0.024 1.99 0.383 0.0479 4.24 4.4087 0.9406 1939654 CBMicro_027926 COc1cc(/C=N/NC(=O)CC2(C)OCCO2)cc(Br)c1OCc3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E09 compound treatment 0.364 0.031 2.57 0.378 0.0429 3.8 4.5063 0.982 1722556 CBMicro_027927 Cc1ccc(O)c(NC(=O)c2cc3nc(cc(C)n3n2)c4ccccc4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E10 compound treatment 0.341 0.008 0.66 0.343 0.00787 0.7 0.9629 0.9997 1235810 CBMicro_027928 COc1ccccc1NC(=O)c2c(NC(=O)Cc3ccccc3)sc4CC(C)CCc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E11 compound treatment 0.34 0.007 0.58 0.34 0.00487 0.43 0.7162 0.9893 1727211 CBMicro_027929 CCOC(=O)c1c(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E12 compound treatment 0.334 0.001 0.08 0.338 0.00287 0.25 0.2386 0.8916 1713875 CBMicro_027930 COc1ccc(cc1)N2C(SCC2=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E13 compound treatment 0.314 -0.019 -1.58 0.319 -0.0161 -1.43 -2.1261 -0.9988 1939655 CBMicro_027931 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E14 compound treatment 0.342 0.009 0.75 0.343 0.00787 0.7 1.0216 0.9994 1939656 CBMicro_027932 COc1ccc(OC)c(c1)C2NC(=S)NC(=C2C(=O)Nc3ccc(Cl)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E15 compound treatment 0.355 0.022 1.83 0.353 0.0179 1.58 2.4114 0.9975 1939657 CBMicro_027933 FC(F)(F)c1ccc2SC(CC(=O)Nc3ccc(cc3)N4CCOCC4)C(=O)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E16 compound treatment 0.345 0.012 1.0 0.34 0.00487 0.43 1.0097 0.93 1630085 CBMicro_027934 Cc1cc(OCC(=O)N2CCC(CC2)C(=O)N)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E17 compound treatment 0.366 0.033 2.74 0.358 0.0229 2.03 3.3704 0.989 1939658 CBMicro_027935 CN(C)c1ccc(/C=C/2\N=C(OC2=O)c3cc4ccccc4oc3=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E18 compound treatment 0.332 -0.001 -0.08 0.333 -0.00213 -0.19 -0.1921 -0.932 1538775 CBMicro_027936 CCc1ccc2NC(=O)C(O)(CC(=O)c3ccc(Br)cc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E19 compound treatment 0.339 0.006 0.5 0.341 0.00587 0.52 0.7201 0.9998 1939659 CBMicro_027937 CC1CCN(CC1)c2ccc(C=C3C(=O)c4ccccc4C3=O)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E20 compound treatment 0.349 0.016 1.33 0.348 0.0129 1.14 1.7458 0.9971 1122218 CBMicro_027938 COc1ccc(CCNC(=O)COc2ccccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E21 compound treatment 0.323 -0.01 -0.83 0.326 -0.00913 -0.81 -1.1591 -0.9999 1258373 CBMicro_027939 CC(NC1CCCCC1)C(O)C2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E22 compound treatment 0.334 0.001 0.08 0.334 -0.00113 -0.1 -0.012 -0.0927 1692427 CBMicro_027940 COc1cccc(c1)C(=O)Nc2cc(OC)cc(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E23 positive control 0.082 -0.251 -20.84 0.083 -0.252 -22.34 -30.5342 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 E24 positive control 0.086 -0.247 -20.51 0.091 -0.244 -21.64 -29.7981 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F01 mock treatment 0.327 -0.006 -0.5 0.33 -0.00513 -0.45 -0.6736 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F02 mock treatment 0.329 -0.004 -0.33 0.334 -0.00113 -0.1 -0.3056 -0.881 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F03 compound treatment 0.328 -0.005 -0.42 0.331 -0.00413 -0.37 -0.5523 -0.998 1446744 CBMicro_027941 CCC1CCc2c(C#N)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F04 compound treatment 0.319 -0.014 -1.16 0.323 -0.0121 -1.07 -1.5819 -0.9992 1939660 CBMicro_027942 CN1/C(=C/C(=O)Nc2ccccc2)/c3ccccc3CC41CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F05 compound treatment 0.338 0.005 0.42 0.337 0.00187 0.17 0.4108 0.919 1939661 CBMicro_027943 CCOC(=O)c1ccc2nc(C)c(C/C=C(/C)\Cl)c(Cl)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F06 compound treatment 0.354 0.021 1.74 0.348 0.0129 1.14 2.0393 0.9789 1939662 CBMicro_027944 COc1ccc(C2=C/C(=C/c3ccc(o3)[N+](=O)[O-])/C(=O)O2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F07 compound treatment 0.332 -0.001 -0.08 0.331 -0.00413 -0.37 -0.3174 -0.846 1939663 CBMicro_027945 CCN(CC)CCCNC(=O)c1cccc(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F08 compound treatment 0.337 0.004 0.33 0.336 8.71E-4 0.08 0.2894 0.8488 1128653 CBMicro_027946 CN1C(C)(C)CC(CC1(C)C)NC(=O)CCC(=O)NC2CC(C)(C)N(C)C(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F09 compound treatment 0.333 0.0 0.0 0.336 8.71E-4 0.08 0.0546 0.7071 1939664 CBMicro_027947 CC(C)N1CCC(=NNC(=O)COc2ccc(Cl)cc2Cl)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F10 compound treatment 0.348 0.015 1.25 0.36 0.0249 2.2 2.4391 0.9635 1322798 CBMicro_027948 CCOC(=O)c1ccc(Nc2cc(ncn2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F11 compound treatment 0.326 -0.007 -0.58 0.325 -0.0101 -0.9 -1.0457 -0.9779 1469894 CBMicro_027949 COc1ccc(C)cc1NC(=O)COc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F12 compound treatment 0.332 -0.001 -0.08 0.332 -0.00313 -0.28 -0.2548 -0.8802 1939665 CBMicro_027950 COc1ccc(cc1OC)C2NC(=S)NC(=C2C(=O)Nc3ccc(Cl)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F13 compound treatment 0.341 0.008 0.66 0.34 0.00487 0.43 0.7749 0.9782 1701786 CBMicro_027951 COc1ccc(OCC(=O)N2CCN(C)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F14 compound treatment 0.342 0.009 0.75 0.342 0.00687 0.61 0.9589 0.9948 1939666 CBMicro_027952 COC(=O)c1ccc(/C=C\2/SC(=O)N(CNc3ccc(OC)c(Cl)c3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F15 compound treatment 0.448 0.115 9.55 0.47 0.135 11.95 15.2026 0.9938 1939667 CBMicro_027953 Cc1cc(C)cc(OCC(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F16 compound treatment 0.345 0.012 1.0 0.336 8.71E-4 0.08 0.759 0.7596 1939668 CBMicro_027954 COc1ccc(cc1)c2nnc(S)n2c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F17 compound treatment 0.344 0.011 0.91 0.338 0.00287 0.25 0.8256 0.8709 1490014 CBMicro_027955 CS(=O)(=O)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F18 compound treatment 0.409 0.076 6.31 0.401 0.0659 5.84 8.5893 0.9992 1245858 CBMicro_027956 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc(C)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F19 compound treatment 0.334 0.001 0.08 0.374 0.0389 3.44 2.4946 0.7239 1939669 CBMicro_027957 CCOC(=O)c1ccc2nc(C)c(CCC(=O)C)c(Cl)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F20 compound treatment 0.337 0.004 0.33 0.339 0.00387 0.34 0.4774 0.9999 1939670 CBMicro_027958 Cc1ccc(cc1)c2nnc(o2)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F21 compound treatment 0.342 0.009 0.75 0.34 0.00487 0.43 0.8336 0.966 1703687 CBMicro_027959 COc1ccc(OCC(=O)NC2CC(C)(C)NC(C)(C)C2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F22 compound treatment 0.348 0.015 1.25 0.349 0.0139 1.23 1.7498 1.0 1174602 CBMicro_027960 COc1ccc(cc1OC)C2(CNC(=O)C(c3ccccc3)c4ccccc4)CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F23 positive control 0.082 -0.251 -20.84 0.085 -0.25 -22.17 -30.4089 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 F24 positive control 0.087 -0.246 -20.42 0.093 -0.242 -21.46 -29.614 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G01 mock treatment 0.322 -0.011 -0.91 0.323 -0.0121 -1.07 -1.4058 -0.9967 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G02 mock treatment 0.335 0.002 0.17 0.33 -0.00513 -0.45 -0.204 -0.4216 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G03 compound treatment 0.324 -0.009 -0.75 0.318 -0.0171 -1.52 -1.6017 -0.9467 1939671 CBMicro_027961 CN1/C(=C\C(=O)Nc2ccc(Br)cc2)/c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G04 compound treatment 0.341 0.008 0.66 0.335 -1.29E-4 -0.01 0.4615 0.6948 1939672 CBMicro_027962 O=C1C2C(C3C=CC2C4CC43)C(=O)N1Cc5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G05 compound treatment 0.337 0.004 0.33 0.336 8.71E-4 0.08 0.2894 0.8488 1301397 CBMicro_027963 NC(=O)c1c(NC(=O)c2cccc(Oc3ccccc3)c2)sc4CCCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G06 compound treatment 0.351 0.018 1.49 0.35 0.0149 1.32 1.9885 0.998 1939673 CBMicro_027964 Cc1nn(c(O)c1/C=N/NCc2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G07 compound treatment 0.33 -0.003 -0.25 0.33 -0.00513 -0.45 -0.4975 -0.9599 1615293 CBMicro_027965 Cc1cc(C)c2nc3sc(=Cc4cc5OCOc5cc4Br)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G08 compound treatment 0.352 0.019 1.58 0.347 0.0119 1.05 1.8593 0.9806 1939674 CBMicro_027966 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(o4)c5ccc(Br)cc5)C(=O)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G09 compound treatment 0.305 -0.028 -2.32 0.307 -0.0281 -2.49 -3.4064 -0.9994 1909360 CBMicro_027967 CC1=C(C(NC(=S)N1)c2ccc(Cl)cc2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G10 compound treatment 0.329 -0.004 -0.33 0.324 -0.0111 -0.99 -0.9322 -0.8958 1939675 CBMicro_027968 Cc1cccc(OCCSc2nc3ccccc3n2CCO)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G11 compound treatment 0.328 -0.005 -0.42 0.349 0.0139 1.23 0.5757 0.4437 1184052 CBMicro_027969 Cc1nc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc2n1Cc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G12 compound treatment 0.336 0.003 0.25 0.331 -0.00413 -0.37 -0.0826 -0.1867 1502259 CBMicro_027970 CCOC(=O)C1=C(NC(=O)NC1c2ccc(CC)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G13 compound treatment 0.326 -0.007 -0.58 0.327 -0.00813 -0.72 -0.9203 -0.9943 1563083 CBMicro_027971 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(F)cc2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G14 compound treatment 0.33 -0.003 -0.25 0.328 -0.00713 -0.63 -0.6229 -0.9172 1939676 CBMicro_027972 Cc1ccc(cc1)n2c(S)nnc2c3cccc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G15 compound treatment 0.403 0.07 5.81 0.389 0.0539 4.77 7.4851 0.9952 1939677 CBMicro_027973 O=C1N/C(=N\c2ccccn2)/SC1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G16 compound treatment 0.38 0.047 3.9 0.397 0.0619 5.48 6.6362 0.9861 1349130 CBMicro_027974 CCCCc1c(C)nc2ccc(OC)cc2c1S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G17 compound treatment 0.379 0.046 3.82 0.38 0.0449 3.98 5.5122 0.9998 1690158 CBMicro_027975 COc1ccc(Cl)cc1N(CC(=O)Nc2cccc3cccnc23)S(=O)(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G18 compound treatment 0.323 -0.01 -0.83 0.334 -0.00113 -0.1 -0.6578 -0.7866 1241596 CBMicro_027976 CCOC(=O)C1=C(C)NC(=S)NC1c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G19 compound treatment 0.367 0.034 2.82 0.384 0.0489 4.33 5.0584 0.9785 1939678 CBMicro_027977 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCc3ccco3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G20 compound treatment 0.334 0.001 0.08 0.333 -0.00213 -0.19 -0.0747 -0.3624 1939679 CBMicro_027978 COc1cccc(c1)c2nc(no2)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G21 compound treatment 0.343 0.01 0.83 0.345 0.00987 0.87 1.2056 0.9997 1521963 CBMicro_027979 CCc1sc(cc1Br)c2c(C#N)c(N)nc3CCCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G22 compound treatment 0.336 0.003 0.25 0.338 0.00287 0.25 0.356 0.9999 1939680 CBMicro_027980 COc1ccc(Cl)cc1C(=O)NN=C2CCN(C)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G23 positive control 0.083 -0.25 -20.75 0.085 -0.25 -22.17 -30.3502 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 G24 positive control 0.09 -0.243 -20.17 0.092 -0.243 -21.55 -29.5006 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H01 mock treatment 0.324 -0.009 -0.75 0.327 -0.00813 -0.72 -1.0377 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H02 mock treatment 0.333 0.0 0.0 0.335 -1.29E-4 -0.01 -0.0081 -0.7071 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H03 compound treatment 0.326 -0.007 -0.58 0.325 -0.0101 -0.9 -1.0457 -0.9779 1939681 CBMicro_027981 CC(CNC(=O)COc1cc(C)cc(C)c1)CN(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H04 compound treatment 0.332 -0.001 -0.08 0.334 -0.00113 -0.1 -0.1295 -0.9957 1110501 CBMicro_027982 CCOC(=O)CNS(=O)(=O)CCN1C(=O)c2ccccc2C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H05 compound treatment 0.339 0.006 0.5 0.338 0.00287 0.25 0.5321 0.9514 1728748 CBMicro_027983 COc1ccc(OCC(=O)Nc2cc(C)ccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H06 compound treatment 0.325 -0.008 -0.66 0.327 -0.00813 -0.72 -0.979 -0.9992 1628981 CBMicro_027984 O=C1CSC(N1)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H07 compound treatment 0.332 -0.001 -0.08 0.328 -0.00713 -0.63 -0.5054 -0.7932 1546234 CBMicro_027985 OC(=O)C1CCCCC1C(=O)Nc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H08 compound treatment 0.348 0.015 1.25 0.352 0.0169 1.5 1.9378 0.9959 1199603 CBMicro_027986 COc1cc(NC(=O)c2cc3nc(cc(C)n3n2)c4ccccc4)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H09 compound treatment 0.318 -0.015 -1.25 0.321 -0.0141 -1.25 -1.7659 -1.0 1939682 CBMicro_027987 Cc1nc(NC(=O)c2ccccc2Br)sc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H10 compound treatment 0.325 -0.008 -0.66 0.322 -0.0131 -1.16 -1.2924 -0.9646 1694148 CBMicro_027988 CCCC1=C(C(NC(=O)N1)c2ccc(Cl)cc2Cl)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H11 compound treatment 0.319 -0.014 -1.16 0.333 -0.00213 -0.19 -0.9553 -0.8113 1939683 CBMicro_027989 COC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3N=C1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H12 compound treatment 0.337 0.004 0.33 0.347 0.0119 1.05 0.9787 0.8872 1939684 CBMicro_027990 COc1ccc(CCNC(=O)/C=C/c2ccc3OCOc3c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H13 compound treatment 0.322 -0.011 -0.91 0.323 -0.0121 -1.07 -1.4058 -0.9967 1674651 CBMicro_027991 COc1ccc(cc1OC)C(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H14 compound treatment 0.326 -0.007 -0.58 0.327 -0.00813 -0.72 -0.9203 -0.9943 1939685 CBMicro_027992 CC(C)N/C(=C/C(=O)ONC(=O)c1ccccc1)/C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H15 compound treatment 0.334 0.001 0.08 0.326 -0.00913 -0.81 -0.5134 -0.6312 1939686 CBMicro_027993 COc1ccc(cc1)C(=O)NNC(=O)c2ccc(OC)cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H16 compound treatment 0.331 -0.002 -0.17 0.329 -0.00613 -0.54 -0.5015 -0.8829 1939687 CBMicro_027994 Cc1nn(c(O)c1C(=O)c2cccc(F)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H17 compound treatment 0.334 0.001 0.08 0.332 -0.00313 -0.28 -0.1374 -0.4746 1939688 CBMicro_027995 COc1ccccc1OCC(=O)NNC(=O)c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H18 compound treatment 0.308 -0.025 -2.08 0.308 -0.0271 -2.4 -3.1676 -0.9973 1728009 CBMicro_027996 CN(C)CCCN1C(SCC1=O)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H19 compound treatment 0.331 -0.002 -0.17 0.329 -0.00613 -0.54 -0.5015 -0.8829 1307122 CBMicro_027997 COc1ccccc1c2nc(no2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H20 compound treatment 0.35 0.017 1.41 0.345 0.00987 0.87 1.6165 0.9735 1195591 CBMicro_027998 CCOc1ccc(Cc2c(C)nc3c(C)cccc3c2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H21 compound treatment 0.356 0.023 1.91 0.355 0.0199 1.76 2.5954 0.9992 1152469 CBMicro_027999 COc1ccc(OCC(=O)Nc2cc3oc4ccccc4c3cc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H22 compound treatment 0.334 0.001 0.08 0.336 8.71E-4 0.08 0.1133 0.9993 1478812 CBMicro_028000 CCSc1nc(NN)c2c3CCN(C)Cc3sc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H23 positive control 0.086 -0.247 -20.51 0.087 -0.248 -21.99 -30.0487 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 H24 positive control 0.09 -0.243 -20.17 0.095 -0.24 -21.28 -29.3126 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I01 mock treatment 0.334 0.001 0.08 0.336 8.71E-4 0.08 0.1133 0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I02 mock treatment 0.336 0.003 0.25 0.342 0.00687 0.61 0.6067 0.9222 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I03 compound treatment 0.408 0.075 6.23 0.414 0.0789 6.99 9.3452 0.9983 1939689 CBMicro_028001 O=C1Nc2ccccc2C31NN=C(S3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I04 compound treatment 0.319 -0.014 -1.16 0.329 -0.00613 -0.54 -1.2059 -0.94 1939690 CBMicro_028002 COc1ccc(cc1)C2SCC(=O)N2c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I05 compound treatment 0.338 0.005 0.42 0.341 0.00587 0.52 0.6614 0.9937 1939691 CBMicro_028003 Fc1ccc(cc1)N2C(=O)CC(NCc3ccc4OCOc4c3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I06 compound treatment 0.433 0.1 8.3 0.434 0.0989 8.76 12.0661 0.9996 1939692 CBMicro_028004 COC(=O)C/1=C(C)NC(=O)\C1=C/c2cccc(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I07 compound treatment 0.32 -0.013 -1.08 0.335 -1.29E-4 -0.01 -0.7712 -0.7146 1295611 CBMicro_028005 CCc1ccc2NC(=O)C(O)(CC(=O)c3ccc(Cl)cc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I08 compound treatment 0.371 0.038 3.15 0.371 0.0359 3.18 4.4786 1.0 1939693 CBMicro_028006 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCc3cccnc3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I09 compound treatment 0.438 0.105 8.72 0.468 0.133 11.78 14.4902 0.989 1939694 CBMicro_028007 CC/1=NN(C(=O)\C1=C/NCCc2c[nH]c3ccccc23)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I10 compound treatment 0.406 0.073 6.06 0.422 0.0869 7.7 9.7291 0.993 1939695 CBMicro_028008 Oc1ccc(/C=C/2\SC(=S)N(C3CCCCC3)C2=O)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I11 compound treatment 0.345 0.012 1.0 0.345 0.00987 0.87 1.323 0.9979 1939696 CBMicro_028009 COc1ccc2n(Cc3ccccc3)c(C)nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I12 compound treatment 0.322 -0.011 -0.91 0.316 -0.0191 -1.7 -1.8445 -0.9579 1939697 CBMicro_028010 COc1ccccc1C(=O)NNC(=O)C(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I13 compound treatment 0.306 -0.027 -2.24 0.312 -0.0231 -2.05 -3.0344 -0.999 1688843 CBMicro_028011 CC(=C)COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I14 compound treatment 0.318 -0.015 -1.25 0.318 -0.0171 -1.52 -1.9539 -0.9952 1496585 CBMicro_028012 Cc1ncc([nH]1)C2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I15 compound treatment 0.408 0.075 6.23 0.398 0.0629 5.57 8.3426 0.9985 1939698 CBMicro_028013 CCN/C(=N\CC)/SC1CC(=O)N(C1=O)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I16 compound treatment 0.339 0.006 0.5 0.336 8.71E-4 0.08 0.4068 0.807 1608491 CBMicro_028014 CN1CCN(CC1)C(=O)COc2ccc(C)cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I17 compound treatment 0.333 0.0 0.0 0.339 0.00387 0.34 0.2426 0.7071 1939699 CBMicro_028015 CC1=C(C(NC(=S)N1)c2ccc(Cl)cc2Cl)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I18 compound treatment 0.319 -0.014 -1.16 0.318 -0.0171 -1.52 -1.8952 -0.9913 1939700 CBMicro_028016 CC1=C(C(NC(=S)N1)c2cccc3ccccc23)C(=O)Nc4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I19 compound treatment 0.319 -0.014 -1.16 0.32 -0.0151 -1.34 -1.7699 -0.9975 1720426 CBMicro_028017 CCOC(=O)C1=C(C)NC(=S)NC1c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I20 compound treatment 0.349 0.016 1.33 0.347 0.0119 1.05 1.6831 0.9933 1514628 CBMicro_028018 Clc1ccc(NCc2ccccc2)c(c1)C(=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I21 compound treatment 0.344 0.011 0.91 0.344 0.00887 0.79 1.2016 0.9972 1939701 CBMicro_028019 Cc1cc2nc3sc(=Cc4ccc(N5CCOCC5)c(c4)[N+](=O)[O-])c(=O)n3c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I22 compound treatment 0.346 0.013 1.08 0.343 0.00787 0.7 1.2564 0.9777 1939702 CBMicro_028020 COc1cc(OC)cc(c1)C(=O)NNC(=O)c2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I23 positive control 0.085 -0.248 -20.59 0.085 -0.25 -22.17 -30.2328 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 I24 positive control 0.089 -0.244 -20.26 0.091 -0.244 -21.64 -29.622 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J01 mock treatment 0.301 -0.032 -2.66 0.309 -0.0261 -2.32 -3.5159 -0.9977 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J02 mock treatment 0.333 0.0 0.0 0.341 0.00587 0.52 0.3679 0.7071 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J03 compound treatment 0.334 0.001 0.08 0.337 0.00187 0.17 0.1759 0.9489 1939703 CBMicro_028021 Clc1ccc(C(=O)N/N=C/2\CC3CCC2C3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J04 compound treatment 0.357 0.024 1.99 0.354 0.0189 1.67 2.5914 0.9962 1350262 CBMicro_028022 COc1cc(cc(OC)c1OC)c2nnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J05 compound treatment 0.3 -0.033 -2.74 0.3 -0.0351 -3.11 -4.1386 -0.998 1939704 CBMicro_028023 COc1cc(OC)cc(c1)C(=O)N/N=C(\C)/CC(=O)Nc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J06 compound treatment 0.343 0.01 0.83 0.343 0.00787 0.7 1.0803 0.9963 1473248 CBMicro_028024 CC1(C)Cc2ccccc2-c3nnc(c4cccc(N)c4)n31 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J07 compound treatment 0.333 0.0 0.0 0.345 0.00987 0.87 0.6186 0.7071 1939705 CBMicro_028025 C/C(=N\NC(=O)C(=O)NC1CCCCC1)/CC(=O)Nc2cccc3CCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J08 compound treatment 0.342 0.009 0.75 0.365 0.0299 2.65 2.4002 0.8726 1939706 CBMicro_028026 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2cc(F)c(F)cc2Cl)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J09 compound treatment 0.336 0.003 0.25 0.334 -0.00113 -0.1 0.1054 0.3925 1058129 CBMicro_028027 OC(=O)c1cc(nc2ccccc12)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J10 compound treatment 0.333 0.0 0.0 0.342 0.00687 0.61 0.4306 0.7071 1939707 CBMicro_028028 CCOC(=O)C1=C(C)N=C2SCC(=O)N2C1c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J11 compound treatment 0.367 0.034 2.82 0.376 0.0409 3.62 4.5571 0.9924 1437517 CBMicro_028029 CCCCc1c(C)nc2ccc(cc2c1S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J12 compound treatment 0.37 0.037 3.07 0.36 0.0249 2.2 3.7306 0.9867 1939708 CBMicro_028030 COc1ccc(cc1)c2cc(n3nc(C(=O)N4CCCCC4)c(Br)c3n2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J13 compound treatment 0.34 0.007 0.58 0.337 0.00187 0.17 0.5282 0.874 1939709 CBMicro_028031 COc1cccc(OCC(=O)NNC(=O)COc2ccccc2OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J14 compound treatment 0.368 0.035 2.91 0.354 0.0189 1.67 3.2372 0.9656 1245090 CBMicro_028032 COc1ccc(Cl)cc1NC(=O)c2cc3nc(cc(C)n3n2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J15 compound treatment 0.34 0.007 0.58 0.336 8.71E-4 0.08 0.4655 0.7941 1308916 CBMicro_028033 COc1cccc(OCC(=O)N2CCN(C)CC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J16 compound treatment 0.34 0.007 0.58 0.342 0.00687 0.61 0.8415 0.9997 1939710 CBMicro_028034 CC(C)C(=O)NNC1(C)CC(=NN1C(=O)C(C)C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J17 compound treatment 0.341 0.008 0.66 0.341 0.00587 0.52 0.8375 0.9927 1252341 CBMicro_028035 COc1cccc2c3SC(C)Cc3c(C)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J18 compound treatment 0.343 0.01 0.83 0.342 0.00687 0.61 1.0176 0.9884 1939711 CBMicro_028036 CN1C(=O)N(C)C(=O)C(=CNCc2cccs2)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J19 compound treatment 0.504 0.171 14.2 0.506 0.171 15.14 20.7459 0.9995 1939712 CBMicro_028037 Nc1ccc(Br)cc1/C(=N/O)/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J20 compound treatment 0.353 0.02 1.66 0.346 0.0109 0.96 1.8553 0.9665 1939713 CBMicro_028038 Cc1nnc(NC(=O)/C=C/c2ccc(F)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J21 compound treatment 0.342 0.009 0.75 0.316 -0.0191 -1.7 -0.6704 -0.3619 1939714 CBMicro_028039 Cc1cc(NC(=O)c2ccccc2Br)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J22 compound treatment 0.349 0.016 1.33 0.346 0.0109 0.96 1.6205 0.9876 1642744 CBMicro_028040 NNc1nc2sc3CCCCc3c2c(=O)n1Cc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J23 positive control 0.086 -0.247 -20.51 0.085 -0.25 -22.17 -30.1741 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 J24 positive control 0.091 -0.242 -20.09 0.092 -0.243 -21.55 -29.4419 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K01 mock treatment 0.329 -0.004 -0.33 0.331 -0.00413 -0.37 -0.4936 -0.9988 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K02 mock treatment 0.33 -0.003 -0.25 0.336 8.71E-4 0.08 -0.1215 -0.4661 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K03 compound treatment 0.316 -0.017 -1.41 0.32 -0.0151 -1.34 -1.946 -0.9997 1939715 CBMicro_028041 CCNC(=S)N(Cc1ccccc1)/N=C\c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K04 compound treatment 0.413 0.08 6.64 0.422 0.0869 7.7 10.14 0.9973 1939716 CBMicro_028042 FC(F)(F)C1(CC(=O)c2ccccc2)NN=C(S1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K05 compound treatment 0.349 0.016 1.33 0.352 0.0169 1.5 1.9965 0.9983 1657729 CBMicro_028043 COC(=O)C1=C(C)NC2=C(C1c3cccs3)C(=O)CC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K06 compound treatment 0.339 0.006 0.5 0.35 0.0149 1.32 1.2841 0.9114 1577297 CBMicro_028044 Cc1ccc(OCCn2c(SCC(=O)N)nc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K07 compound treatment 0.328 -0.005 -0.42 0.336 8.71E-4 0.08 -0.2389 -0.5659 1939717 CBMicro_028045 CC(C)(C)c1csc(NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K08 compound treatment 0.337 0.004 0.33 0.338 0.00287 0.25 0.4147 0.9914 1453550 CBMicro_028046 Cc1nc2ccccc2c(=O)n1c3ccccc3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K09 compound treatment 0.333 0.0 0.0 0.337 0.00187 0.17 0.1172 0.7071 1225017 CBMicro_028047 CC1CC(Nc2ccccc2)N(N1c3ccccc3)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K10 compound treatment 0.339 0.006 0.5 0.339 0.00387 0.34 0.5948 0.9834 1939718 CBMicro_028048 COc1ccc(cc1OC)C2NN=C(Cc3ccccc3)S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K11 compound treatment 0.339 0.006 0.5 0.35 0.0149 1.32 1.2841 0.9114 1939719 CBMicro_028049 CCOC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K12 compound treatment 0.332 -0.001 -0.08 0.331 -0.00413 -0.37 -0.3174 -0.846 1939720 CBMicro_028050 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K13 compound treatment 0.336 0.003 0.25 0.341 0.00587 0.52 0.544 0.9431 1939721 CBMicro_028051 CC1(C)Cc2ccccc2-c3nnc(c4ccccc4Cl)n31 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K14 compound treatment 0.39 0.057 4.73 0.398 0.0629 5.57 7.2859 0.9967 1939722 CBMicro_028052 OC(=O)c1cccc(c1)c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K15 compound treatment 0.338 0.005 0.42 0.343 0.00787 0.7 0.7868 0.9693 1939723 CBMicro_028053 Cc1cc(C)c2nc3sc(=Cc4cc(Br)ccc4O)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K16 compound treatment 0.346 0.013 1.08 0.348 0.0129 1.14 1.5697 0.9996 1150085 CBMicro_028054 O=C(Nc1ccc(cc1)C(=O)Nc2ccncc2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K17 compound treatment 0.313 -0.02 -1.66 0.312 -0.0231 -2.05 -2.6234 -0.9945 1939724 CBMicro_028055 Cc1ccc(OCCCCNC(=O)C(O)(c2ccc(F)cc2)c3ccc(F)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K18 compound treatment 0.91 0.577 47.9 0.912 0.577 51.12 70.0215 0.9995 1939725 CBMicro_028056 COc1cc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccs3)cc2)nc(OC)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K19 compound treatment 0.359 0.026 2.16 0.381 0.0459 4.07 4.4008 0.9561 1592303 CBMicro_028057 CC(C)C(=O)Nc1ccc2oc3ccccc3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K20 compound treatment 0.372 0.039 3.24 0.376 0.0409 3.62 4.8506 0.9984 1686932 CBMicro_028058 c1ccc(cc1)c2ccc(cc2)c3nc(no3)c4cccnc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K21 compound treatment 0.334 0.001 0.08 0.34 0.00487 0.43 0.3639 0.8279 1153282 CBMicro_028059 OC(=O)c1[nH]cnc1C(=O)Nc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K22 compound treatment 0.34 0.007 0.58 0.338 0.00287 0.25 0.5908 0.9313 1162567 CBMicro_028060 OC(=O)c1cccc(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K23 positive control 0.09 -0.243 -20.17 0.087 -0.248 -21.99 -29.8139 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 K24 positive control 0.093 -0.24 -19.92 0.095 -0.24 -21.28 -29.1365 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L01 mock treatment 0.329 -0.004 -0.33 0.332 -0.00313 -0.28 -0.4309 -0.996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L02 mock treatment 0.332 -0.001 -0.08 0.336 8.71E-4 0.08 -0.0041 -0.0364 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L03 compound treatment 0.334 0.001 0.08 0.329 -0.00613 -0.54 -0.3254 -0.5922 1939726 CBMicro_028061 [O-][N+](=O)c1cc(cc(c1)c2nnc(o2)c3ccc(Br)o3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L04 compound treatment 0.335 0.002 0.17 0.338 0.00287 0.25 0.2973 0.9786 1939727 CBMicro_028062 CC1=C(C(NC(=O)N1)c2cccc3ccccc23)C(=O)Nc4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L05 compound treatment 0.338 0.005 0.42 0.34 0.00487 0.43 0.5988 0.9998 1673935 CBMicro_028063 COc1ccccc1OCC(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L06 compound treatment 0.35 0.017 1.41 0.386 0.0509 4.51 4.1858 0.8861 1336851 CBMicro_028064 CC1CC(Nc2ccc(C)cc2)c3cc(C)ccc3N1C(=O)c4cccc(F)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L07 compound treatment 0.336 0.003 0.25 0.332 -0.00313 -0.28 -0.02 -0.0536 1585160 CBMicro_028065 CCCOc1ccc2nc(C)c(CCC)c(Cl)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L08 compound treatment 0.336 0.003 0.25 0.335 -1.29E-4 -0.01 0.168 0.6739 1939728 CBMicro_028066 Clc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L09 compound treatment 0.331 -0.002 -0.17 0.331 -0.00413 -0.37 -0.3762 -0.9361 1662417 CBMicro_028067 Cc1ccc(nc1)N2C(=O)c3ccc(cc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L10 compound treatment 0.411 0.078 6.48 0.423 0.0879 7.79 10.0853 0.9958 1939729 CBMicro_028068 CC(Nc1cc(ccc1[N+](=O)[O-])N2CCN(CCO)CC2)C3(C[C@H]4C[C@@H]5C[C@H](C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L11 compound treatment 0.331 -0.002 -0.17 0.327 -0.00813 -0.72 -0.6268 -0.8479 1408587 CBMicro_028069 CCC(C)(C)C1CCc2c(C#N)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L12 compound treatment 0.339 0.006 0.5 0.332 -0.00313 -0.28 0.1561 0.2739 1939730 CBMicro_028070 CN(C)/C=N/C1=NN(CC1)c2cccc(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L13 compound treatment 0.347 0.014 1.16 0.347 0.0119 1.05 1.5657 0.9988 1939731 CBMicro_028071 CCSc1nnc(NC(=O)/C=C/c2ccc(F)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L14 compound treatment 0.335 0.002 0.17 0.336 8.71E-4 0.08 0.172 0.9393 1726857 CBMicro_028072 CC1(C)Cc2c(CO1)sc3[nH]c(=S)n(Cc4ccccc4)c(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L15 compound treatment 0.343 0.01 0.83 0.343 0.00787 0.7 1.0803 0.9963 1552961 CBMicro_028073 COc1cc(cc(OC)c1OC)C(=O)OCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L16 compound treatment 0.35 0.017 1.41 0.369 0.0339 3.0 3.1205 0.9408 1555923 CBMicro_028074 NNc1nc2sc3CCCc3c2c(=O)n1Cc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L17 compound treatment 0.353 0.02 1.66 0.352 0.0169 1.5 2.2313 0.9986 1939732 CBMicro_028075 CCOc1ccc2nc(C)c(C/C=C(/C)\Cl)c(Cl)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L18 compound treatment 0.37 0.037 3.07 0.368 0.0329 2.91 4.2319 0.9996 1776488 CBMicro_028076 CCOC(=O)c1ccc(NC(=O)/C(=C/2\NC(C)(C)Cc3ccccc23)/C#N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L19 compound treatment 0.36 0.027 2.24 0.349 0.0139 1.23 2.4542 0.96 1663055 CBMicro_028077 CC(C)(C)C1CCc2c(C#N)c(NC(=O)C3CCCO3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L20 compound treatment 0.358 0.025 2.08 0.35 0.0149 1.32 2.3995 0.976 1939733 CBMicro_028078 Cc1ccc(NC(=S)NC(=O)/C=C/c2ccco2)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L21 compound treatment 0.376 0.043 3.57 0.38 0.0449 3.98 5.3361 0.9986 1164095 CBMicro_028079 Ic1ccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L22 compound treatment 0.346 0.013 1.08 0.343 0.00787 0.7 1.2564 0.9777 1939734 CBMicro_028080 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L23 positive control 0.085 -0.248 -20.59 0.091 -0.244 -21.64 -29.8568 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 L24 positive control 0.091 -0.242 -20.09 0.095 -0.24 -21.28 -29.2539 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M01 mock treatment 0.33 -0.003 -0.25 0.331 -0.00413 -0.37 -0.4349 -0.9824 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M02 mock treatment 0.329 -0.004 -0.33 0.334 -0.00113 -0.1 -0.3056 -0.881 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M03 compound treatment 0.677 0.344 28.56 0.665 0.33 29.23 40.8653 0.9999 1939735 CBMicro_028081 CCCN(C=O)/N=C/c1ccc(cc1O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M04 compound treatment 0.335 0.002 0.17 0.335 -1.29E-4 -0.01 0.1093 0.6569 1780351 CBMicro_028082 CN(C)CCCN1C(SCC1=O)c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M05 compound treatment 0.323 -0.01 -0.83 0.326 -0.00913 -0.81 -1.1591 -0.9999 1939736 CBMicro_028083 O=C/1N(Cc2ccccc2)C(=S)S\C1=C/c3c[nH]c4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M06 compound treatment 0.34 0.007 0.58 0.339 0.00387 0.34 0.6535 0.9684 1602331 CBMicro_028084 CCNC(=S)Nc1sc2CCCc2c1C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M07 compound treatment 0.407 0.074 6.14 0.403 0.0679 6.01 8.5972 0.9999 1939737 CBMicro_028085 COc1ccc(OC)c(c1)C2=C/C(=C/c3cccc(OC)c3O)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M08 compound treatment 0.336 0.003 0.25 0.329 -0.00613 -0.54 -0.208 -0.348 1400314 CBMicro_028086 OC(=O)c1ccc(CN2CCOCC2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M09 compound treatment 0.339 0.006 0.5 0.332 -0.00313 -0.28 0.1561 0.2739 1939738 CBMicro_028087 COC(=O)C1=C(C)NC(=O)NC1c2ccccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M10 compound treatment 0.328 -0.005 -0.42 0.323 -0.0121 -1.07 -1.0536 -0.9144 1939739 CBMicro_028088 Cc1c(Br)c(nn1CC(=O)NCc2cccs2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M11 compound treatment 0.343 0.01 0.83 0.339 0.00387 0.34 0.8296 0.9236 1939740 CBMicro_028089 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=O)CN3CCN(C)CC3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M12 compound treatment 0.334 0.001 0.08 0.331 -0.00413 -0.37 -0.2 -0.5331 1780762 CBMicro_028090 Cc1c(cccc1[N+](=O)[O-])C(=O)NCCC2=CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M13 compound treatment 0.325 -0.008 -0.66 0.328 -0.00713 -0.63 -0.9164 -0.9997 1650792 CBMicro_028091 COc1ccc(OC)c(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M14 compound treatment 0.356 0.023 1.91 0.336 8.71E-4 0.08 1.4048 0.7351 1743304 CBMicro_028092 COc1ccc(cc1)c2c3C(=O)c4ccccc4C(=O)c3c(c5ccccc5)n2c6ccc(cc6)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M15 compound treatment 0.399 0.066 5.48 0.395 0.0599 5.31 7.6262 0.9999 1939741 CBMicro_028093 COC(=O)C/1=C(C)N(CC(C)C)C(=O)\C1=C/c2cc(OC)c(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M16 compound treatment 0.341 0.008 0.66 0.337 0.00187 0.17 0.5869 0.8573 1146196 CBMicro_028094 COc1cc(OC)cc(c1)C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M17 compound treatment 0.343 0.01 0.83 0.337 0.00187 0.17 0.7043 0.8319 1939742 CBMicro_028095 Cc1ccc(OCCSc2nc3ccccc3n2CCO)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M18 compound treatment 0.339 0.006 0.5 0.336 8.71E-4 0.08 0.4068 0.807 1939743 CBMicro_028096 Cc1cc(C)c2nc3sc(=Cc4ccc(Br)cc4)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M19 compound treatment 0.339 0.006 0.5 0.333 -0.00213 -0.19 0.2188 0.4108 1939744 CBMicro_028097 CC1=C(C(NC(=O)N1)c2cccc(Br)c2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M20 compound treatment 0.367 0.034 2.82 0.354 0.0189 1.67 3.1785 0.9688 1939745 CBMicro_028098 Clc1ccc(/C=N/N=C(c2ccccc2)c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M21 compound treatment 0.277 -0.056 -4.65 0.267 -0.0681 -6.04 -7.5567 -0.9917 1939746 CBMicro_028099 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(C3=O)c4cccc(F)c4)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M22 compound treatment 0.341 0.008 0.66 0.336 8.71E-4 0.08 0.5242 0.784 1309549 CBMicro_028100 COc1ccccc1OCC(=O)Nc2cc3oc4ccccc4c3cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M23 positive control 0.085 -0.248 -20.59 0.09 -0.245 -21.72 -29.9195 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 M24 positive control 0.091 -0.242 -20.09 0.099 -0.236 -20.93 -29.0032 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N01 mock treatment 0.339 0.006 0.5 0.34 0.00487 0.43 0.6575 0.9975 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N02 mock treatment 0.335 0.002 0.17 0.339 0.00387 0.34 0.36 0.9445 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N03 compound treatment 0.341 0.008 0.66 0.341 0.00587 0.52 0.8375 0.9927 1939747 CBMicro_028101 C/C(=N\NC(=O)c1ccccc1Cl)/CC(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N04 compound treatment 0.349 0.016 1.33 0.35 0.0149 1.32 1.8711 1.0 1939748 CBMicro_028102 COc1cccc(/C=C\2/C=C(OC2=O)c3ccc(C)cc3)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N05 compound treatment 0.339 0.006 0.5 0.343 0.00787 0.7 0.8455 0.9864 1939749 CBMicro_028103 Cc1ccc(cc1)c2nnc(o2)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N06 compound treatment 0.342 0.009 0.75 0.339 0.00387 0.34 0.7709 0.9377 1939750 CBMicro_028104 COCc1cccc(c1)N2C(=O)c3cccc([N+](=O)[O-])c3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N07 compound treatment 0.346 0.013 1.08 0.341 0.00587 0.52 1.131 0.944 1609732 CBMicro_028105 COc1ccc(OCC(=O)N2CCC(CC2)C(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N08 compound treatment 0.349 0.016 1.33 0.347 0.0119 1.05 1.6831 0.9933 1300282 CBMicro_028106 CCOC(=O)c1c(NC(=S)NCc2ccccc2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N09 compound treatment 0.356 0.023 1.91 0.349 0.0139 1.23 2.2194 0.9773 1939751 CBMicro_028107 COc1ccccc1c2nc(no2)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N10 compound treatment 0.411 0.078 6.48 0.397 0.0619 5.48 8.456 0.9966 1939752 CBMicro_028108 Oc1ccc(/C=C/2\Sc3ccccc3C2=O)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N11 compound treatment 0.353 0.02 1.66 0.345 0.00987 0.87 1.7926 0.9552 1477699 CBMicro_028109 COc1ccc(cc1)C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N12 compound treatment 0.375 0.042 3.49 0.371 0.0359 3.18 4.7134 0.9989 1939753 CBMicro_028110 Cc1nn(c(N2CCCCC2)c1/C=N/O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N13 compound treatment 0.357 0.024 1.99 0.358 0.0229 2.03 2.8421 1.0 1939754 CBMicro_028111 CC(C)N1CCC(=NNC(=O)c2cccc(c2)[N+](=O)[O-])CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N14 compound treatment 0.361 0.028 2.32 0.358 0.0229 2.03 3.0769 0.9977 1368352 CBMicro_028112 CCn1c(SCC(=O)OC)nc2sc3CCCc3c2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N15 compound treatment 0.33 -0.003 -0.25 0.331 -0.00413 -0.37 -0.4349 -0.9824 1939755 CBMicro_028113 Fc1cc(Br)ccc1NC(=O)C(Sc2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N16 compound treatment 0.326 -0.007 -0.58 0.321 -0.0141 -1.25 -1.2963 -0.9391 1622757 CBMicro_028114 CCSc1nc2sc3CN(C)CCc3c2c4nncn14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N17 compound treatment 0.334 0.001 0.08 0.333 -0.00213 -0.19 -0.0747 -0.3624 1408211 CBMicro_028115 CN(C)CCNC(=O)c1ccccc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N18 compound treatment 0.372 0.039 3.24 0.366 0.0309 2.74 4.224 0.9965 1298264 CBMicro_028116 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5ccc(OC)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N19 compound treatment 0.393 0.06 4.98 0.386 0.0509 4.51 6.71 0.9988 1939756 CBMicro_028117 CC(=O)CCc1c(C)nc2ccc(Br)cc2c1S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N20 compound treatment 0.344 0.011 0.91 0.341 0.00587 0.52 1.0136 0.9644 1457330 CBMicro_028118 COc1ccccc1OCC(=O)NCc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N21 compound treatment 0.376 0.043 3.57 0.393 0.0579 5.13 6.1507 0.9843 1939757 CBMicro_028119 CC(=O)Nc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6cc(ccc65)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N22 compound treatment 0.345 0.012 1.0 0.34 0.00487 0.43 1.0097 0.93 1537095 CBMicro_028120 CCc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N23 positive control 0.087 -0.246 -20.42 0.087 -0.248 -21.99 -29.99 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 N24 positive control 0.09 -0.243 -20.17 0.095 -0.24 -21.28 -29.3126 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O01 mock treatment 0.337 0.004 0.33 0.338 0.00287 0.25 0.4147 0.9914 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O02 mock treatment 0.341 0.008 0.66 0.34 0.00487 0.43 0.7749 0.9782 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O03 compound treatment 0.373 0.04 3.32 0.37 0.0349 3.09 4.5333 0.9994 1625183 CBMicro_028121 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)Cc4cccc5ccccc45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O04 compound treatment 0.34 0.007 0.58 0.34 0.00487 0.43 0.7162 0.9893 1681480 CBMicro_028122 CC(C)Cc1nn2c(=O)cc(O)nc2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O05 compound treatment 0.336 0.003 0.25 0.337 0.00187 0.17 0.2934 0.9805 1295962 CBMicro_028123 CCc1sc(cc1Br)c2c(C#N)c(N)nc3CCCCc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O06 compound treatment 0.344 0.011 0.91 0.342 0.00687 0.61 1.0763 0.9806 1939758 CBMicro_028124 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O07 compound treatment 0.384 0.051 4.23 0.43 0.0949 8.41 8.939 0.9496 1370166 CBMicro_028125 CCOc1ccc2-c3c(ssc3=Nc4ccccc4O)C(C)(C)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O08 compound treatment 0.334 0.001 0.08 0.332 -0.00313 -0.28 -0.1374 -0.4746 1777764 CBMicro_028126 COc1ccc(CNC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O09 compound treatment 0.162 -0.171 -14.2 0.17 -0.165 -14.63 -20.3861 -0.9999 1939759 CBMicro_028127 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C/c3nc4ccccc4[nH]3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O10 compound treatment 0.338 0.005 0.42 0.335 -1.29E-4 -0.01 0.2854 0.6874 1939760 CBMicro_028128 Cc1ccc(OCC(=O)NCCCN2CCOCC2)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O11 compound treatment 0.346 0.013 1.08 0.341 0.00587 0.52 1.131 0.944 1939761 CBMicro_028129 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4)cc(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O12 compound treatment 0.354 0.021 1.74 0.352 0.0169 1.5 2.29 0.9971 1491294 CBMicro_028130 CCc1cccc(C)c1NC(=O)c2c(C)onc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O13 compound treatment 0.359 0.026 2.16 0.356 0.0209 1.85 2.8342 0.997 1939762 CBMicro_028131 CC1(NN=C(S1)c2ccccc2)C3CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O14 compound treatment 0.35 0.017 1.41 0.347 0.0119 1.05 1.7419 0.9895 1542079 CBMicro_028132 COc1ccc(OCC(=O)Nc2ccc(OC)c(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O15 compound treatment 0.334 0.001 0.08 0.328 -0.00713 -0.63 -0.388 -0.609 1638402 CBMicro_028133 CN(C)CCCN1C(SCC1=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O16 compound treatment 0.35 0.017 1.41 0.352 0.0169 1.5 2.0552 0.9996 1260587 CBMicro_028134 Fc1ccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O17 compound treatment 0.342 0.009 0.75 0.34 0.00487 0.43 0.8336 0.966 1939763 CBMicro_028135 CC1CC(O)N(N1C)C(=O)c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O18 compound treatment 0.341 0.008 0.66 0.324 -0.0111 -0.99 -0.2278 -0.1916 1689014 CBMicro_028136 Cc1onc(c1C(=O)Nc2cccc(Br)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O19 compound treatment 0.347 0.014 1.16 0.34 0.00487 0.43 1.1271 0.9091 1939764 CBMicro_028137 COc1cc(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O20 compound treatment 0.34 0.007 0.58 0.34 0.00487 0.43 0.7162 0.9893 1939765 CBMicro_028138 CC(=O)CCc1c(C)c2cccc(C)c2[nH]c1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O21 compound treatment 0.346 0.013 1.08 0.344 0.00887 0.79 1.319 0.9879 1939766 CBMicro_028139 CN1CCN(CC1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O22 compound treatment 0.343 0.01 0.83 0.34 0.00487 0.43 0.8923 0.9536 1321701 CBMicro_028140 COc1ccccc1C(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O23 positive control 0.086 -0.247 -20.51 0.086 -0.249 -22.08 -30.1114 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 O24 positive control 0.091 -0.242 -20.09 0.093 -0.242 -21.46 -29.3792 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P01 mock treatment 0.339 0.006 0.5 0.336 8.71E-4 0.08 0.4068 0.807 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P02 mock treatment 0.341 0.008 0.66 0.341 0.00587 0.52 0.8375 0.9927 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P03 compound treatment 0.347 0.014 1.16 0.346 0.0109 0.96 1.5031 0.9957 1331001 CBMicro_028141 COc1cc(OC)cc(c1)C(=O)Nc2cc3oc4ccccc4c3cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P04 compound treatment 0.347 0.014 1.16 0.344 0.00887 0.79 1.3777 0.9819 1939767 CBMicro_028142 CCOC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P05 compound treatment 0.343 0.01 0.83 0.341 0.00587 0.52 0.9549 0.9747 1709093 CBMicro_028143 COc1ccccc1OCC(=O)NCCc2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P06 compound treatment 0.359 0.026 2.16 0.359 0.0239 2.12 3.0222 0.9999 1939768 CBMicro_028144 COc1ccc(NCN2C(=O)S/C(=C/c3ccc(SC)cc3)/C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P07 compound treatment 0.342 0.009 0.75 0.343 0.00787 0.7 1.0216 0.9994 1577566 CBMicro_028145 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3cccs3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P08 compound treatment 0.384 0.051 4.23 0.374 0.0389 3.44 5.4297 0.9948 1394480 CBMicro_028146 CSc1nc2sc3CN(C)CCc3c2c4nnnn14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P09 compound treatment 0.444 0.111 9.22 0.441 0.106 9.38 13.1505 1.0 1243534 CBMicro_028147 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(F)c(F)c3)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P10 compound treatment 0.339 0.006 0.5 0.338 0.00287 0.25 0.5321 0.9514 1939769 CBMicro_028148 Cc1ccc(SC(CC(=O)O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P11 compound treatment 0.357 0.024 1.99 0.363 0.0279 2.47 3.1554 0.9943 1939770 CBMicro_028149 COc1ccc(cc1)C(=O)NNC(=O)c2cc(OC)cc(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P12 compound treatment 0.331 -0.002 -0.17 0.332 -0.00313 -0.28 -0.3135 -0.9699 1939771 CBMicro_028150 Cc1cc(C)c2nc3sc(=Cc4ccc(Cl)cc4)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P13 compound treatment 0.349 0.016 1.33 0.35 0.0149 1.32 1.8711 1.0 1780773 CBMicro_028151 CCOc1ccccc1N2CCN(CC2)C(=O)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P14 compound treatment 0.345 0.012 1.0 0.34 0.00487 0.43 1.0097 0.93 1456691 CBMicro_028152 CC1(C)CC2(CCO1)NCCN3C2SCC3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P15 compound treatment 0.369 0.036 2.99 0.365 0.0299 2.65 3.9852 0.9982 1741201 CBMicro_028153 Cc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc(Br)o4)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P16 compound treatment 0.347 0.014 1.16 0.339 0.00387 0.34 1.0644 0.8784 1727840 CBMicro_028154 CCOC(=O)CSCc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P17 compound treatment 0.339 0.006 0.5 0.341 0.00587 0.52 0.7201 0.9998 1686524 CBMicro_028155 Cc1cccc(N2CCN(CC2)C(=O)c3ccc(Cl)cc3Cl)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P18 compound treatment 0.331 -0.002 -0.17 0.332 -0.00313 -0.28 -0.3135 -0.9699 1668155 CBMicro_028156 O=c1[nH]c(=S)[nH]c2-c3ccccc3CC4(CCCC4)c21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P19 compound treatment 0.336 0.003 0.25 0.333 -0.00213 -0.19 0.0427 0.1366 1264178 CBMicro_028157 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P20 compound treatment 0.368 0.035 2.91 0.364 0.0289 2.56 3.8638 0.998 1469455 CBMicro_028158 CCCCc1c(C)nc2ccc(OC)cc2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P21 compound treatment 0.341 0.008 0.66 0.341 0.00587 0.52 0.8375 0.9927 1939772 CBMicro_028159 O=C(NCc1cccnc1)C(=O)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P22 compound treatment 0.338 0.005 0.42 0.337 0.00187 0.17 0.4108 0.919 1939773 CBMicro_028160 COc1cccc(c1)c2nc(no2)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P23 positive control 0.088 -0.245 -20.34 0.091 -0.244 -21.64 -29.6807 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.773 P24 positive control 0.093 -0.24 -19.92 0.094 -0.241 -21.37 -29.1992 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A01 mock treatment 0.323 -0.0134 -1.11 0.32 -0.0207 -1.83 -2.0811 -0.9709 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A02 mock treatment 0.322 -0.0144 -1.19 0.333 -0.0077 -0.68 -1.3252 -0.965 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A03 compound treatment 0.322 -0.0144 -1.19 0.321 -0.0197 -1.75 -2.0772 -0.9827 1939774 CBMicro_028161 COc1cccc(/C=C/2\SC(=S)N(C3CCCCC3)C2=O)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A04 compound treatment 0.323 -0.0134 -1.11 0.327 -0.0137 -1.21 -1.6425 -0.999 1665140 CBMicro_028162 Clc1ccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A05 compound treatment 0.323 -0.0134 -1.11 0.321 -0.0197 -1.75 -2.0185 -0.976 1939775 CBMicro_028163 COc1ccccc1C(=O)N/N=C(\C)/c2ccc(C)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A06 compound treatment 0.325 -0.0114 -0.94 0.325 -0.0157 -1.39 -1.6504 -0.982 1161566 CBMicro_028164 COC(=O)c1ccc(C(=O)OC)c(NC(=O)C(C)Oc2ccc(Cl)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A07 compound treatment 0.332 -0.00435 -0.36 0.336 -0.0047 -0.42 -0.5502 -0.9975 1939776 CBMicro_028165 C(=N/N=C(c1ccccc1)c2ccccc2)\c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A08 compound treatment 0.32 -0.0164 -1.36 0.317 -0.0237 -2.1 -2.4452 -0.9777 1939777 CBMicro_028166 CCc1ccc(OCCSc2nc3ccccc3[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A09 compound treatment 0.311 -0.0254 -2.1 0.312 -0.0287 -2.54 -3.2869 -0.9956 1939778 CBMicro_028167 OC(=O)c1ccc(/C=N/NC(=O)C(=O)N2CCCCCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A10 compound treatment 0.324 -0.0124 -1.03 0.326 -0.0147 -1.3 -1.6464 -0.993 1612728 CBMicro_028168 Cc1sc(NC(=O)COc2ccccc2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A11 compound treatment 0.317 -0.0194 -1.61 0.316 -0.0247 -2.19 -2.684 -0.9884 1350126 CBMicro_028169 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A12 compound treatment 0.318 -0.0184 -1.52 0.317 -0.0237 -2.1 -2.5627 -0.9876 1329676 CBMicro_028170 COc1ccc(OCC(=O)Nc2ccccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A13 compound treatment 0.32 -0.0164 -1.36 0.324 -0.0167 -1.48 -2.0066 -0.9991 1939779 CBMicro_028171 CCOc1cc(Br)cc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A14 compound treatment 0.323 -0.0134 -1.11 0.317 -0.0237 -2.1 -2.2691 -0.9554 1357497 CBMicro_028172 O=C(Nc1sc2CCCCCc2c1C#N)C3CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A15 compound treatment 0.332 -0.00435 -0.36 0.323 -0.0177 -1.57 -1.3648 -0.8479 1599023 CBMicro_028173 Cc1cccc(N2CCN(CC2)C(=O)c3cccs3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A16 compound treatment 0.322 -0.0144 -1.19 0.324 -0.0167 -1.48 -1.8892 -0.9942 1939780 CBMicro_028174 COc1ccc(cc1)C(=O)NNC(=O)c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A17 compound treatment 0.317 -0.0194 -1.61 0.319 -0.0217 -1.92 -2.496 -0.996 1694944 CBMicro_028175 COc1cccc(c1)C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A18 compound treatment 0.325 -0.0114 -0.94 0.321 -0.0197 -1.75 -1.9011 -0.9582 1051780 CBMicro_028176 OC(=O)C1CCCCC1C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A19 compound treatment 0.332 -0.00435 -0.36 0.328 -0.0127 -1.13 -1.0515 -0.8895 1441263 CBMicro_028177 COC(=O)C1=C(C)N(C(=C(C1c2ccc(OC)cc2)C(=O)OC)C)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A20 compound treatment 0.346 0.00965 0.8 0.348 0.0073 0.65 1.0237 0.9944 1611933 CBMicro_028178 NC(=O)c1c(NS(=O)(=O)c2ccc(Br)cc2)sc3CCCCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A21 compound treatment 0.311 -0.0254 -2.1 0.313 -0.0277 -2.45 -3.2242 -0.9971 1939781 CBMicro_028179 COc1cccc(c1)c2nc(no2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A22 compound treatment 0.321 -0.0154 -1.27 0.318 -0.0227 -2.01 -2.3239 -0.9758 1268823 CBMicro_028180 CCSc1nnc(NC(=O)CCC2CCCCC2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A23 positive control 0.082 -0.254 -21.12 0.082 -0.259 -22.93 -31.1429 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 A24 positive control 0.084 -0.252 -20.95 0.086 -0.255 -22.57 -30.7749 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B01 mock treatment 0.324 -0.0124 -1.03 0.333 -0.0077 -0.68 -1.2078 -0.9804 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B02 mock treatment 0.337 6.45E-4 0.05 0.347 0.0063 0.56 0.4327 0.7714 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B03 compound treatment 0.332 -0.00435 -0.36 0.329 -0.0117 -1.04 -0.9888 -0.9005 1939782 CBMicro_028181 [O-][N+](=O)c1ccc(cc1)c2csc(NC(=O)CCCOc3ccc(Cl)cc3Cl)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B04 compound treatment 0.339 0.00265 0.22 0.335 -0.0057 -0.51 -0.2019 -0.3666 1939783 CBMicro_028182 CCn1c(SCC(=O)c2ccc(Cl)cc2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B05 compound treatment 0.329 -0.00735 -0.61 0.325 -0.0157 -1.39 -1.4156 -0.9317 1517551 CBMicro_028183 CCOC(=O)c1c(C)c(sc1NC(=O)C(C)C)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B06 compound treatment 0.331 -0.00535 -0.44 0.325 -0.0157 -1.39 -1.2982 -0.8888 1652401 CBMicro_028184 O=C(c1ccc(cc1)S(=O)(=O)N2CCCCC2)n3c(SCC#C)nc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B07 compound treatment 0.337 6.45E-4 0.05 0.335 -0.0057 -0.51 -0.3193 -0.6286 1628945 CBMicro_028185 Cc1c(NS(=O)(=O)c2ccc(C)cc2C)c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B08 compound treatment 0.323 -0.0134 -1.11 0.315 -0.0257 -2.28 -2.3945 -0.9453 1939784 CBMicro_028186 Clc1ccc(C2NN=C(Cc3ccccc3)S2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B09 compound treatment 0.351 0.0146 1.22 0.344 0.0033 0.29 1.0665 0.8529 1939785 CBMicro_028187 [O-][N+](=O)c1ccc(NC(=O)CCC2CCCCC2)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B10 compound treatment 0.326 -0.0104 -0.86 0.324 -0.0167 -1.48 -1.6544 -0.9666 1939786 CBMicro_028188 CC(=O)Nc1cc(Oc2cccc(C)c2)cc(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B11 compound treatment 0.338 0.00165 0.14 0.334 -0.0067 -0.59 -0.3233 -0.5306 1617992 CBMicro_028189 CCOC(=O)c1sc(NC(=O)c2ccc(C)o2)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B12 compound treatment 0.33 -0.00635 -0.53 0.325 -0.0157 -1.39 -1.3569 -0.9119 1939787 CBMicro_028190 COC(=O)c1sccc1NS(=O)(=O)c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B13 compound treatment 0.356 0.0196 1.63 0.353 0.0123 1.09 1.924 0.9808 1508236 CBMicro_028191 CCC(C)(C)C1CCc2c(C#N)c(NC(=O)C(C)C)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B14 compound treatment 0.355 0.0186 1.55 0.366 0.0253 2.24 2.68 0.9836 1939788 CBMicro_028192 CCOC(=O)c1c(NC(=O)Nc2ccccc2)sc3CCCCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B15 compound treatment 0.378 0.0416 3.46 0.352 0.0113 1.0 3.1528 0.8759 1939789 CBMicro_028193 Clc1ccc(/C=N/NC(=O)CCC(=O)N\N=C\c2ccc(Cl)s2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B16 compound treatment 0.341 0.00465 0.39 0.342 0.0013 0.12 0.3542 0.8799 1459825 CBMicro_028194 OC(=O)C1CCCCC1C(=O)N2CCN(CC2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B17 compound treatment 0.342 0.00565 0.47 0.343 0.0023 0.2 0.4755 0.9305 1241535 CBMicro_028195 CC1CC(C)CN(C1)C(=O)c2cc(nc3ccccc23)c4ccc(C)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B18 compound treatment 0.371 0.0346 2.88 0.363 0.0223 1.98 3.4312 0.9832 1218535 CBMicro_028196 COc1ccc(c(OC)c1)c2cc(C(=O)Nc3ccc(Br)cc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B19 compound treatment 0.347 0.0106 0.88 0.348 0.0073 0.65 1.0824 0.9882 1707914 CBMicro_028197 COc1ccc(c(OC)c1)c2cc(C(=O)NCCN3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B20 compound treatment 0.33 -0.00635 -0.53 0.326 -0.0147 -1.3 -1.2942 -0.9208 1291389 CBMicro_028198 Clc1cc(Cl)cc(NC(=O)c2ccc3OCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B21 compound treatment 0.335 -0.00135 -0.11 0.331 -0.0097 -0.86 -0.6874 -0.7929 1358919 CBMicro_028199 COc1cc(OC)cc(c1)C(=O)Nc2ccccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B22 compound treatment 0.345 0.00865 0.72 0.341 3.0E-4 0.03 0.5263 0.7328 1477998 CBMicro_028200 COC(=O)c1cc(NC(=O)C(C)Oc2ccc(Cl)cc2C)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B23 positive control 0.083 -0.253 -21.03 0.082 -0.259 -22.93 -31.0842 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 B24 positive control 0.084 -0.252 -20.95 0.083 -0.258 -22.84 -30.9629 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C01 mock treatment 0.339 0.00265 0.22 0.342 0.0013 0.12 0.2367 0.9547 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C02 mock treatment 0.347 0.0106 0.88 0.356 0.0153 1.36 1.5837 0.9785 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C03 compound treatment 0.317 -0.0194 -1.61 0.304 -0.0367 -3.25 -3.436 -0.9472 1939790 CBMicro_028201 [O-][N+](=O)c1ncn(CC(=O)N2CCN(Cc3ccccc3)CC2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C04 compound treatment 0.337 6.45E-4 0.05 0.333 -0.0077 -0.68 -0.4446 -0.6496 1939791 CBMicro_028202 CCCN1CCC(=NNC(=O)CCC(=O)NN=C2CCN(CCC)CC2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C05 compound treatment 0.337 6.45E-4 0.05 0.333 -0.0077 -0.68 -0.4446 -0.6496 1143913 CBMicro_028203 Cc1onc(c1C(=O)N2CCc3ccccc23)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C06 compound treatment 0.33 -0.00635 -0.53 0.323 -0.0177 -1.57 -1.4822 -0.8956 1141209 CBMicro_028204 CN(Cc1ccccc1)C(=O)c2cc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C07 compound treatment 0.337 6.45E-4 0.05 0.332 -0.0087 -0.77 -0.5073 -0.6564 1939792 CBMicro_028205 O=C(NCC1CCCO1)/C=C/c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C08 compound treatment 0.327 -0.00935 -0.78 0.324 -0.0167 -1.48 -1.5957 -0.9547 1939793 CBMicro_028206 CN(C)c1ccc(/C=C\2/SC(=S)N(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C09 compound treatment 0.381 0.0446 3.71 0.377 0.0363 3.22 4.8956 0.9975 1939794 CBMicro_028207 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C3CC(=O)N(C3=O)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C10 compound treatment 0.356 0.0196 1.63 0.352 0.0113 1.0 1.8614 0.9726 1939795 CBMicro_028208 COc1ccc(cc1)c2cc(C(=O)Nc3ccccc3C(F)(F)F)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C11 compound treatment 0.346 0.00965 0.8 0.329 -0.0117 -1.04 -0.167 -0.1275 1669456 CBMicro_028209 CCc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3cc(C)cc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C12 compound treatment 0.344 0.00765 0.63 0.341 3.0E-4 0.03 0.4676 0.7361 1939796 CBMicro_028210 O=C(NCCCc1ccccc1)c2cc3ccccc3oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C13 compound treatment 0.327 -0.00935 -0.78 0.323 -0.0177 -1.57 -1.6583 -0.9474 1367047 CBMicro_028211 CN1C(CC(=O)Nc2ccccc2C)c3ccccc3CC1(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C14 compound treatment 0.348 0.0116 0.97 0.343 0.0023 0.2 0.8277 0.8378 1939797 CBMicro_028212 O=S(=O)(N1CCN(C/C=C/c2ccccc2)CC1)c3cccc4cccnc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C15 compound treatment 0.352 0.0156 1.3 0.38 0.0393 3.48 3.3812 0.9096 1939798 CBMicro_028213 Cc1nc(NC(=O)/C=C/c2ccc(F)cc2)sc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C16 compound treatment 0.336 -3.55E-4 -0.03 0.335 -0.0057 -0.51 -0.378 -0.7471 1626241 CBMicro_028214 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3CCCO3)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C17 compound treatment 0.336 -3.55E-4 -0.03 0.334 -0.0067 -0.59 -0.4407 -0.7413 1146519 CBMicro_028215 COc1ccc(cc1OC)C(=O)Nc2ccccc2CO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C18 compound treatment 0.336 -3.55E-4 -0.03 0.333 -0.0077 -0.68 -0.5034 -0.7369 1939799 CBMicro_028216 N/C(=N\C(=O)c1ccccc1)/Nc2nc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C19 compound treatment 0.333 -0.00335 -0.28 0.331 -0.0097 -0.86 -0.8048 -0.8906 1939800 CBMicro_028217 CC(C)N1CCC(=NNC(=O)c2ccc(cc2)C(C)(C)C)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C20 compound treatment 0.338 0.00165 0.14 0.338 -0.0027 -0.24 -0.0726 -0.2636 1939801 CBMicro_028218 COC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2Cl)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C21 compound treatment 0.343 0.00665 0.55 0.338 -0.0027 -0.24 0.2209 0.3673 1939802 CBMicro_028219 C/C(=N\NC(=O)c1ccccc1I)/CC(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C22 compound treatment 0.334 -0.00235 -0.2 0.333 -0.0077 -0.68 -0.6208 -0.8745 1650558 CBMicro_028220 Cc1cccc(c1)c2cc(C(=O)n3cccn3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C23 positive control 0.083 -0.253 -21.03 0.081 -0.26 -23.02 -31.1469 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 C24 positive control 0.088 -0.248 -20.62 0.086 -0.255 -22.57 -30.54 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D01 mock treatment 0.336 -3.55E-4 -0.03 0.339 -0.0017 -0.15 -0.1274 -0.8297 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D02 mock treatment 0.341 0.00465 0.39 0.346 0.0053 0.47 0.6048 0.9952 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D03 compound treatment 0.343 0.00665 0.55 0.34 -7.0E-4 -0.06 0.3462 0.6237 1153596 CBMicro_028221 OC(=O)C1CCCCC1C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D04 compound treatment 0.347 0.0106 0.88 0.344 0.0033 0.29 0.8317 0.8935 1939803 CBMicro_028222 CSc1nc2sc3CN(Cc4ccccc4)CCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D05 compound treatment 0.317 -0.0194 -1.61 0.316 -0.0247 -2.19 -2.684 -0.9884 1939804 CBMicro_028223 Nc1cc(Cl)c(cc1S(=O)(=O)Nc2ccccc2)S(=O)(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D06 compound treatment 0.524 0.188 15.58 0.525 0.184 16.33 22.5646 0.9997 1939805 CBMicro_028224 Oc1ccccc1C2=NNC3(S2)C(=O)Nc4ccccc43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D07 compound treatment 0.323 -0.0134 -1.11 0.318 -0.0227 -2.01 -2.2065 -0.9606 1399608 CBMicro_028225 COC(=O)c1sccc1NC(=O)CCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D08 compound treatment 0.34 0.00365 0.3 0.331 -0.0097 -0.86 -0.3939 -0.4322 1939806 CBMicro_028226 Oc1ccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D09 compound treatment 0.338 0.00165 0.14 0.335 -0.0057 -0.51 -0.2606 -0.498 1382149 CBMicro_028227 CCOc1cc(cc(OCC)c1OCC)C(=O)NC2CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D10 compound treatment 0.35 0.0136 1.13 0.346 0.0053 0.47 1.1331 0.924 1939807 CBMicro_028228 COc1cccc(/C=N/NC(=O)C(=O)N2CCCCCC2)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D11 compound treatment 0.351 0.0146 1.22 0.347 0.0063 0.56 1.2545 0.9377 1466006 CBMicro_028229 Cc1ccc2c(Cl)c(sc2c1)C(=O)N3CCN(CC3)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D12 compound treatment 0.35 0.0136 1.13 0.345 0.0043 0.38 1.0705 0.8957 1463525 CBMicro_028230 Cc1occc1C(=O)Nc2sc3CC(CCc3c2C(=O)N)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D13 compound treatment 0.336 -3.55E-4 -0.03 0.331 -0.0097 -0.86 -0.6287 -0.7309 1939808 CBMicro_028231 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(C)c2)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D14 compound treatment 0.342 0.00565 0.47 0.339 -0.0017 -0.15 0.2249 0.4568 1278901 CBMicro_028232 Cc1onc(c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccc(C)n3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D15 compound treatment 0.341 0.00465 0.39 0.326 -0.0147 -1.3 -0.6485 -0.4773 1339388 CBMicro_028233 CCc1ccc(NC(=O)c2c(C)onc2c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D16 compound treatment 0.325 -0.0114 -0.94 0.334 -0.0067 -0.59 -1.0864 -0.9752 1502888 CBMicro_028234 Cc1onc(c1C(=O)NCCC(c2ccccc2)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D17 compound treatment 0.345 0.00865 0.72 0.354 0.0133 1.18 1.3409 0.9717 1371073 CBMicro_028235 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cc(ccc2C(=O)OC)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D18 compound treatment 0.348 0.0116 0.97 0.345 0.0043 0.38 0.9531 0.9172 1601161 CBMicro_028236 Clc1ccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D19 compound treatment 0.344 0.00765 0.63 0.345 0.0043 0.38 0.7183 0.9702 1365704 CBMicro_028237 O=C(Nc1nc(cs1)c2ccc(cc2)c3ccccc3)C4CC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D20 compound treatment 0.343 0.00665 0.55 0.345 0.0043 0.38 0.6596 0.9837 1661462 CBMicro_028238 CC(C)(C)c1ccc(cc1)C(=O)Nc2sc3CCCCCCc3c2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D21 compound treatment 0.353 0.0166 1.38 0.357 0.0163 1.44 1.9986 0.9998 1939809 CBMicro_028239 O=C(Nc1nc(cs1)c2ccc3ccccc3c2)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D22 compound treatment 0.332 -0.00435 -0.36 0.326 -0.0147 -1.3 -1.1768 -0.8704 1264917 CBMicro_028240 NC(=O)c1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D23 positive control 0.085 -0.251 -20.87 0.082 -0.259 -22.93 -30.9668 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 D24 positive control 0.089 -0.247 -20.54 0.087 -0.254 -22.48 -30.4187 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E01 mock treatment 0.323 -0.0134 -1.11 0.331 -0.0097 -0.86 -1.3918 -0.9921 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E02 mock treatment 0.349 0.0126 1.05 0.347 0.0063 0.56 1.1371 0.9563 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E03 compound treatment 0.303 -0.0334 -2.77 0.318 -0.0227 -2.01 -3.3805 -0.9877 1939810 CBMicro_028241 Cc1cc(C)c2nc3sc(=Cc4ccc(o4)c5ccc(Cl)c(c5)C(=O)O)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E04 compound treatment 0.331 -0.00535 -0.44 0.322 -0.0187 -1.66 -1.4862 -0.8662 1249176 CBMicro_028242 Cc1onc(c1C(=O)NCc2ccc(Cl)c(Cl)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E05 compound treatment 0.305 -0.0314 -2.6 0.299 -0.0417 -3.7 -4.4538 -0.9853 1939811 CBMicro_028243 C/C(=N/NC(=O)c1c[nH]c2ccccc12)/c3cccc(NC(=O)c4ccco4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E06 compound treatment 0.324 -0.0124 -1.03 0.319 -0.0217 -1.92 -2.0851 -0.9567 1939812 CBMicro_028244 COC(=O)c1cc(NC(=O)/C=C/c2ccc(F)cc2)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E07 compound treatment 0.335 -0.00135 -0.11 0.337 -0.0037 -0.33 -0.3114 -0.8983 1632110 CBMicro_028245 CCC(=O)N1CC(=O)Nc2ccc(C)cc2C1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E08 compound treatment 0.354 0.0176 1.46 0.331 -0.0097 -0.86 0.428 0.252 1939813 CBMicro_028246 Oc1ccc(Br)cc1/C=N/Nc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E09 compound treatment 0.316 -0.0204 -1.69 0.311 -0.0297 -2.63 -3.056 -0.9771 1939814 CBMicro_028247 CC1=C(C(NC(=S)N1)c2cccc(Br)c2)C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E10 compound treatment 0.352 0.0156 1.3 0.34 -7.0E-4 -0.06 0.8746 0.6726 1367265 CBMicro_028248 CCC(C(=O)Nc1sc(C(=O)OC(C)C)c(C)c1C#N)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E11 compound treatment 0.35 0.0136 1.13 0.327 -0.0137 -1.21 -0.0575 -0.0346 1939815 CBMicro_028249 OC(=O)c1cccc(c1)c2ccc(/C=C/3\SC(=S)N(C3=O)c4cccc(F)c4)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E12 compound treatment 0.33 -0.00635 -0.53 0.334 -0.0067 -0.59 -0.7929 -0.9983 1620576 CBMicro_028250 c1ccc(cc1)c2ccc(cc2)c3nc(no3)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E13 compound treatment 0.325 -0.0114 -0.94 0.332 -0.0087 -0.77 -1.2118 -0.995 1132979 CBMicro_028251 COc1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3ccc(Cl)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E14 compound treatment 0.329 -0.00735 -0.61 0.332 -0.0087 -0.77 -0.9769 -0.9933 1939816 CBMicro_028252 COc1ccccc1c2nc(no2)c3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E15 compound treatment 0.284 -0.0524 -4.35 0.279 -0.0617 -5.47 -6.9398 -0.9935 1939817 CBMicro_028253 CCOC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E16 compound treatment 0.341 0.00465 0.39 0.335 -0.0057 -0.51 -0.0845 -0.133 1939818 CBMicro_028254 C/C(=N\NC(=O)c1ccc(cc1)c2ccccc2)/CC(=O)NC3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E17 compound treatment 0.345 0.00865 0.72 0.354 0.0133 1.18 1.3409 0.9717 1487874 CBMicro_028255 COc1ccc(cc1OC)C(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E18 compound treatment 0.333 -0.00335 -0.28 0.339 -0.0017 -0.15 -0.3035 -0.9584 1293601 CBMicro_028256 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2nnn[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E19 compound treatment 0.326 -0.0104 -0.86 0.324 -0.0167 -1.48 -1.6544 -0.9666 1939819 CBMicro_028257 CCOC(=O)c1ccc2nc(C)c(CCC(=O)C)c(O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E20 compound treatment 0.334 -0.00235 -0.2 0.335 -0.0057 -0.51 -0.4954 -0.9147 1197906 CBMicro_028258 OC(=O)C1C(C2OC1C=C2)C(=O)NCc3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E21 compound treatment 0.358 0.0216 1.8 0.35 0.0093 0.82 1.8534 0.9375 1213359 CBMicro_028259 COc1ccc(cc1OC)c2cc(C(=O)NC3CCCCCCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E22 compound treatment 0.32 -0.0164 -1.36 0.329 -0.0117 -1.04 -1.6933 -0.9911 1170060 CBMicro_028260 CCc1ccc(cc1)c2cc(C(=O)NC3CC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E23 positive control 0.084 -0.252 -20.95 0.082 -0.259 -22.93 -31.0255 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 E24 positive control 0.088 -0.248 -20.62 0.088 -0.253 -22.39 -30.4147 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F01 mock treatment 0.33 -0.00635 -0.53 0.334 -0.0067 -0.59 -0.7929 -0.9983 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F02 mock treatment 0.336 -3.55E-4 -0.03 0.341 3.0E-4 0.03 -0.002 -0.0512 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F03 compound treatment 0.376 0.0396 3.29 0.372 0.0313 2.77 4.2887 0.9964 1327167 CBMicro_028261 COc1ccc(CCNC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F04 compound treatment 0.331 -0.00535 -0.44 0.33 -0.0107 -0.95 -0.9849 -0.9404 1666191 CBMicro_028262 COc1cccc(c1)C(=O)NCc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F05 compound treatment 0.323 -0.0134 -1.11 0.32 -0.0207 -1.83 -2.0811 -0.9709 1425752 CBMicro_028263 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F06 compound treatment 0.344 0.00765 0.63 0.343 0.0023 0.2 0.5929 0.8895 1939820 CBMicro_028264 CNC(=S)N(C)/N=C/c1c(Cl)cccc1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F07 compound treatment 0.357 0.0206 1.71 0.354 0.0133 1.18 2.0454 0.9833 1388523 CBMicro_028265 COc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F08 compound treatment 0.345 0.00865 0.72 0.344 0.0033 0.29 0.7143 0.9217 1939821 CBMicro_028266 COc1ccc(OC)c(/C=N/NC(=O)C(=O)N2CCCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F09 compound treatment 0.37 0.0336 2.79 0.378 0.0373 3.31 4.3125 0.9965 1939822 CBMicro_028267 Cc1ccc(cc1)S(=O)(=O)NNc2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F10 compound treatment 0.319 -0.0174 -1.44 0.325 -0.0157 -1.39 -2.0026 -0.9998 1939823 CBMicro_028268 Oc1cccc(/C=N/NC(=O)C(=O)N2CCCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F11 compound treatment 0.346 0.00965 0.8 0.349 0.0083 0.74 1.0863 0.9991 1475223 CBMicro_028269 COc1ccc(Cl)cc1NC(=O)c2cc(nc3ccccc23)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F12 compound treatment 0.327 -0.00935 -0.78 0.322 -0.0187 -1.66 -1.721 -0.9403 1939824 CBMicro_028270 Cc1cc(NC(=O)c2ccc(Cl)cc2[N+](=O)[O-])no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F13 compound treatment 0.355 0.0186 1.55 0.355 0.0143 1.27 1.9906 0.9951 1324497 CBMicro_028271 O=C(Nc1sc2CCCCCc2c1C#N)C3c4ccccc4Oc5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F14 compound treatment 0.378 0.0416 3.46 0.381 0.0403 3.57 4.9701 0.9999 1653372 CBMicro_028272 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cc(nc4ccccc34)c5ccc(Br)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F15 compound treatment 0.384 0.0476 3.96 0.378 0.0373 3.31 5.1343 0.996 1711314 CBMicro_028273 CC1CCc2c(C(=O)N)c(NC(=O)CC(c3ccccc3)c4ccccc4)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F16 compound treatment 0.344 0.00765 0.63 0.343 0.0023 0.2 0.5929 0.8895 1277710 CBMicro_028274 CC(C)OC(=O)c1sc(NC(=O)c2ccccc2F)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F17 compound treatment 0.331 -0.00535 -0.44 0.333 -0.0077 -0.68 -0.7969 -0.9784 1939825 CBMicro_028275 Fc1ccc(/C=C/C(=O)N2CCN(CC2)c3ccc(Cl)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F18 compound treatment 0.362 0.0256 2.13 0.359 0.0183 1.62 2.6522 0.991 1939826 CBMicro_028276 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F19 compound treatment 0.326 -0.0104 -0.86 0.316 -0.0247 -2.19 -2.1557 -0.9166 1939827 CBMicro_028277 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F20 compound treatment 0.349 0.0126 1.05 0.361 0.0203 1.8 2.0144 0.9671 1385444 CBMicro_028278 CCOc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F21 compound treatment 0.314 -0.0224 -1.86 0.319 -0.0217 -1.92 -2.6721 -0.9998 1939828 CBMicro_028279 CC1=CC(C)(C)N(C(=S)NC(=O)c2ccccc2)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F22 compound treatment 0.334 -0.00235 -0.2 0.337 -0.0037 -0.33 -0.3701 -0.9695 1245112 CBMicro_028280 CCOc1ccc(cc1)c2cc(C(=O)Nc3cc(OC)c(Cl)cc3OC)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F23 positive control 0.084 -0.252 -20.95 0.084 -0.257 -22.75 -30.9002 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 F24 positive control 0.088 -0.248 -20.62 0.087 -0.254 -22.48 -30.4774 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G01 mock treatment 0.322 -0.0144 -1.19 0.326 -0.0147 -1.3 -1.7639 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G02 mock treatment 0.333 -0.00335 -0.28 0.337 -0.0037 -0.33 -0.4288 -0.9967 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G03 compound treatment 0.35 0.0136 1.13 0.348 0.0073 0.65 1.2585 0.9647 1939829 CBMicro_028281 COc1cc(/C=N\n2nnnc2N)ccc1OCc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G04 compound treatment 0.335 -0.00135 -0.11 0.333 -0.0077 -0.68 -0.5621 -0.8127 1406537 CBMicro_028282 CCOc1ccc2nc(SCC(=O)c3ccc(F)cc3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G05 compound treatment 0.34 0.00365 0.3 0.342 0.0013 0.12 0.2954 0.9124 1326555 CBMicro_028283 Clc1ccc2nc(NC(=O)C3CC3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G06 compound treatment 0.332 -0.00435 -0.36 0.334 -0.0067 -0.59 -0.6755 -0.9717 1620676 CBMicro_028284 Clc1ccc(NC(=O)N2CCN(CC2)c3ccc(Cl)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G07 compound treatment 0.342 0.00565 0.47 0.341 3.0E-4 0.03 0.3502 0.746 1939830 CBMicro_028285 Cn1cccc1CC(=O)N/N=C/c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G08 compound treatment 0.315 -0.0214 -1.77 0.321 -0.0197 -1.75 -2.4881 -1.0 1939831 CBMicro_028286 COc1ccc(/N=C/c2cccc(C)c2O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G09 compound treatment 0.326 -0.0104 -0.86 0.325 -0.0157 -1.39 -1.5917 -0.9732 1939832 CBMicro_028287 CC(=O)c1c(C)nn(c1O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G10 compound treatment 0.327 -0.00935 -0.78 0.326 -0.0147 -1.3 -1.4703 -0.9695 1463877 CBMicro_028288 Clc1ccc(NC(=O)NN2CCOCC2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G11 compound treatment 0.33 -0.00635 -0.53 0.322 -0.0187 -1.66 -1.5449 -0.8883 1939833 CBMicro_028289 FC(F)(F)c1cc(nc2c(cnn12)C(=O)Nc3sc4CCCCc4c3C#N)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G12 compound treatment 0.349 0.0126 1.05 0.334 -0.0067 -0.59 0.3225 0.2674 1939834 CBMicro_028290 FC(F)(F)c1ccccc1/C=N/NC(=O)CCC(=O)N\N=C\c2ccccc2C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G13 compound treatment 0.324 -0.0124 -1.03 0.329 -0.0117 -1.04 -1.4585 -1.0 1781224 CBMicro_028291 [O-][N+](=O)c1cccc(c1)C(=O)COC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G14 compound treatment 0.329 -0.00735 -0.61 0.327 -0.0137 -1.21 -1.2903 -0.9494 1939835 CBMicro_028292 COc1ccccc1OCC(=O)NNC(=O)Cc2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G15 compound treatment 0.336 -3.55E-4 -0.03 0.342 0.0013 0.12 0.0606 0.5099 1939836 CBMicro_028293 COc1ccc(Br)cc1/C=N/NC(=O)c2c[nH]c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G16 compound treatment 0.333 -0.00335 -0.28 0.328 -0.0127 -1.13 -0.9928 -0.8563 1939837 CBMicro_028294 COc1ccc(/C=C(\NC(=O)c2ccccc2Br)/C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G17 compound treatment 0.331 -0.00535 -0.44 0.332 -0.0087 -0.77 -0.8595 -0.9658 1939838 CBMicro_028295 COc1ccc(OCC(=O)NCCCN2CCOCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G18 compound treatment 0.33 -0.00635 -0.53 0.327 -0.0137 -1.21 -1.2316 -0.9303 1939839 CBMicro_028296 O/N=C(\C(=O)NCCN1CCCCC1)/c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G19 compound treatment 0.282 -0.0544 -4.51 0.284 -0.0567 -5.02 -6.7439 -0.9986 1534613 CBMicro_028297 COc1ccc(cc1OC)C(=O)NCCN(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G20 compound treatment 0.326 -0.0104 -0.86 0.326 -0.0147 -1.3 -1.529 -0.9796 1373307 CBMicro_028298 COc1ccc(cc1OC)c2cc(C(=O)NN3CCN(C)CC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G21 compound treatment 0.355 0.0186 1.55 0.348 0.0073 0.65 1.552 0.9251 1939840 CBMicro_028299 Oc1cccc(NC(=S)NC(=O)/C=C/c2ccc(F)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G22 compound treatment 0.32 -0.0164 -1.36 0.32 -0.0207 -1.83 -2.2573 -0.989 1939841 CBMicro_028300 NC(=O)c1c(NC(=O)c2ccccc2[N+](=O)[O-])sc3CCCCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G23 positive control 0.086 -0.25 -20.78 0.086 -0.255 -22.57 -30.6575 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 G24 positive control 0.093 -0.243 -20.2 0.092 -0.249 -22.04 -29.8705 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H01 mock treatment 0.327 -0.00935 -0.78 0.331 -0.0097 -0.86 -1.157 -0.9987 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H02 mock treatment 0.341 0.00465 0.39 0.345 0.0043 0.38 0.5421 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H03 compound treatment 0.326 -0.0104 -0.86 0.322 -0.0187 -1.66 -1.7797 -0.9533 1600442 CBMicro_028301 O=S(=O)(Nc1nccs1)c2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H04 compound treatment 0.341 0.00465 0.39 0.341 3.0E-4 0.03 0.2915 0.7541 1208501 CBMicro_028302 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H05 compound treatment 0.316 -0.0204 -1.69 0.314 -0.0267 -2.37 -2.8681 -0.9864 1939842 CBMicro_028303 Clc1ccc(NC(=O)NCCCn2ccnc2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H06 compound treatment 0.37 0.0336 2.79 0.342 0.0013 0.12 2.0565 0.7356 1939843 CBMicro_028304 CSc1ccccc1NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H07 compound treatment 0.308 -0.0284 -2.35 0.302 -0.0387 -3.43 -4.0897 -0.9831 1428974 CBMicro_028305 Nc1cc(Cl)c(cc1S(=O)(=O)NC2CCCCC2)S(=O)(=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H08 compound treatment 0.347 0.0106 0.88 0.33 -0.0107 -0.95 -0.0456 -0.0352 1264978 CBMicro_028306 Fc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H09 compound treatment 0.335 -0.00135 -0.11 0.326 -0.0147 -1.3 -1.0007 -0.7653 1445742 CBMicro_028307 CCOc1ccccc1N2CCN(CC2)C(=O)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H10 compound treatment 0.324 -0.0124 -1.03 0.326 -0.0147 -1.3 -1.6464 -0.993 1939844 CBMicro_028308 [O-][N+](=O)c1cc(Cl)ccc1c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H11 compound treatment 0.308 -0.0284 -2.35 0.305 -0.0357 -3.16 -3.9017 -0.9894 1170872 CBMicro_028309 Clc1ccc(Cl)c(c1)C(=O)NCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H12 compound treatment 0.324 -0.0124 -1.03 0.318 -0.0227 -2.01 -2.1478 -0.9511 1939845 CBMicro_028310 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H13 compound treatment 0.389 0.0526 4.37 0.407 0.0663 5.88 7.2451 0.9894 1939846 CBMicro_028311 [O-][N+](=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H14 compound treatment 0.33 -0.00635 -0.53 0.33 -0.0107 -0.95 -1.0436 -0.9617 1517333 CBMicro_028312 Cc1onc(c1C(=O)NCCC(c2ccccc2)c3ccccc3)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H15 compound treatment 0.328 -0.00835 -0.69 0.319 -0.0217 -1.92 -1.8503 -0.9051 1939847 CBMicro_028313 O=C(N/N=C\c1ccc[nH]1)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H16 compound treatment 0.323 -0.0134 -1.11 0.323 -0.0177 -1.57 -1.8931 -0.9856 1191126 CBMicro_028314 COc1cccc(OC)c1C(=O)Nc2sc(C)c(C)c2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H17 compound treatment 0.372 0.0356 2.96 0.372 0.0313 2.77 4.0539 0.9995 1939848 CBMicro_028315 Cc1ccc(cc1)c2csc(NC(=O)c3sc4cc(C)ccc4c3Cl)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H18 compound treatment 0.393 0.0566 4.7 0.397 0.0563 4.99 6.8533 0.9996 1725472 CBMicro_028316 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H19 compound treatment 0.307 -0.0294 -2.44 0.307 -0.0337 -2.99 -3.835 -0.9949 1939849 CBMicro_028317 [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)/N=C/2\C=CC(=O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H20 compound treatment 0.351 0.0146 1.22 0.351 0.0103 0.91 1.5052 0.99 1939850 CBMicro_028318 OC(=O)c1ccc(cc1)N2C(=O)c3cccc4c([N+](=O)[O-])c(O)cc(C2=O)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H21 compound treatment 0.384 0.0476 3.96 0.378 0.0373 3.31 5.1343 0.996 1216844 CBMicro_028319 CC(Oc1ccc(Cl)cc1Cl)C(=O)N2CCN(CC2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H22 compound treatment 0.335 -0.00135 -0.11 0.334 -0.0067 -0.59 -0.4994 -0.8264 1733450 CBMicro_028320 O=C(NCc1ccccc1)c2cc(nc3ccccc23)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H23 positive control 0.086 -0.25 -20.78 0.085 -0.256 -22.66 -30.7201 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 H24 positive control 0.092 -0.244 -20.29 0.092 -0.249 -22.04 -29.9292 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I01 mock treatment 0.339 0.00265 0.22 0.34 -7.0E-4 -0.06 0.1114 0.4882 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I02 mock treatment 0.344 0.00765 0.63 0.347 0.0063 0.56 0.8436 0.998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I03 compound treatment 0.339 0.00265 0.22 0.337 -0.0037 -0.33 -0.0766 -0.1941 1939851 CBMicro_028321 Cc1cc(C)c2nc3sc(=Cc4ccc(o4)c5cc([N+](=O)[O-])c(C)cc5C)c(=O)n3c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I04 compound treatment 0.334 -0.00235 -0.2 0.327 -0.0137 -1.21 -0.9967 -0.8105 1939852 CBMicro_028322 c1ccc(cc1)c2noc(n2)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I05 compound treatment 0.332 -0.00435 -0.36 0.327 -0.0137 -1.21 -1.1142 -0.8795 1244834 CBMicro_028323 COc1ccc(OCC(=O)Nc2cc(OC)cc(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I06 compound treatment 0.317 -0.0194 -1.61 0.314 -0.0267 -2.37 -2.8094 -0.9822 1939853 CBMicro_028324 O=S(=O)(NNc1ccccc1)c2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I07 compound treatment 0.332 -0.00435 -0.36 0.33 -0.0107 -0.95 -0.9262 -0.9126 1939854 CBMicro_028325 COc1ccc(cc1OC)C(=O)NNC(=O)c2cccc(C)c2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I08 compound treatment 0.5 0.164 13.59 0.663 0.322 28.56 29.8035 0.9423 1939855 CBMicro_028326 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I09 compound treatment 0.308 -0.0284 -2.35 0.305 -0.0357 -3.16 -3.9017 -0.9894 1508843 CBMicro_028327 CN1C(C)(C)CC(CC1(C)C)OC(=O)c2ccccc2C(=O)OC3CC(C)(C)N(C)C(C)(C)C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I10 compound treatment 0.327 -0.00935 -0.78 0.321 -0.0197 -1.75 -1.7837 -0.9335 1939856 CBMicro_028328 C/C(=N/NC(=O)c1ccccc1C)/c2ccc(NC(=O)C(F)(F)F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I11 compound treatment 0.351 0.0146 1.22 0.345 0.0043 0.38 1.1292 0.8862 1939857 CBMicro_028329 CCCCOC(=O)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I12 compound treatment 0.426 0.0896 7.44 0.42 0.0793 7.03 10.2318 0.9996 1939858 CBMicro_028330 CC(=O)CCc1c(C)c2ccccc2[nH]c1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I13 compound treatment 0.322 -0.0144 -1.19 0.326 -0.0147 -1.3 -1.7639 -0.999 1939859 CBMicro_028331 CN1CCC(=NNC(=O)c2cccc(C)c2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I14 compound treatment 0.329 -0.00735 -0.61 0.325 -0.0157 -1.39 -1.4156 -0.9317 1613520 CBMicro_028332 COc1cccc(OCC(=O)Nc2cc(OC)cc(OC)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I15 compound treatment 0.344 0.00765 0.63 0.353 0.0123 1.09 1.2196 0.9669 1289339 CBMicro_028333 CCNc1ccc(Br)cc1C(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I16 compound treatment 0.348 0.0116 0.97 0.349 0.0083 0.74 1.2037 0.9909 1217594 CBMicro_028334 CCCCc1c(C)nc2ccc(cc2c1Cl)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I17 compound treatment 0.335 -0.00135 -0.11 0.334 -0.0067 -0.59 -0.4994 -0.8264 1594155 CBMicro_028335 COc1ccccc1OCC(=O)Nc2ccc(cc2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I18 compound treatment 0.334 -0.00235 -0.2 0.339 -0.0017 -0.15 -0.2448 -0.9917 1939860 CBMicro_028336 CC1CCc2c(C#N)c(NC(=O)Nc3cccc(Cl)c3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I19 compound treatment 0.331 -0.00535 -0.44 0.328 -0.0127 -1.13 -1.1102 -0.9174 1239949 CBMicro_028337 COc1cccc(c1)C(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I20 compound treatment 0.343 0.00665 0.55 0.341 3.0E-4 0.03 0.4089 0.7403 1660930 CBMicro_028338 CCc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I21 compound treatment 0.333 -0.00335 -0.28 0.33 -0.0107 -0.95 -0.8675 -0.8777 1606871 CBMicro_028339 COc1cccc(c1)C(=O)Nc2ccccc2CO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I22 compound treatment 0.335 -0.00135 -0.11 0.338 -0.0027 -0.24 -0.2487 -0.9407 1445216 CBMicro_028340 OC(=O)C1CC=CCC1C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I23 positive control 0.086 -0.25 -20.78 0.086 -0.255 -22.57 -30.6575 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 I24 positive control 0.091 -0.245 -20.37 0.092 -0.249 -22.04 -29.9879 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J01 mock treatment 0.31 -0.0264 -2.19 0.308 -0.0327 -2.9 -3.5963 -0.9904 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J02 mock treatment 0.338 0.00165 0.14 0.343 0.0023 0.2 0.2407 0.981 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J03 compound treatment 0.344 0.00765 0.63 0.348 0.0073 0.65 0.9063 1.0 1939861 CBMicro_028341 CCN(CC)C(=O)c1sc(NC(=O)/C=C/c2cccs2)c(C(=O)OC(C)C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J04 compound treatment 0.335 -0.00135 -0.11 0.335 -0.0057 -0.51 -0.4367 -0.8439 1939862 CBMicro_028342 CN1C2CCC1CC(=NOC(=O)c3ccc(F)cc3)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J05 compound treatment 0.333 -0.00335 -0.28 0.334 -0.0067 -0.59 -0.6168 -0.9405 1939863 CBMicro_028343 CC1CCc2c(C#N)c(NC(=O)c3c(F)c(F)c(F)c(F)c3F)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J06 compound treatment 0.436 0.0996 8.27 0.44 0.0993 8.8 12.0721 0.9995 1939864 CBMicro_028344 OC(=O)c1nn2c(cc(nc2c1Cl)c3cccs3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J07 compound treatment 0.341 0.00465 0.39 0.335 -0.0057 -0.51 -0.0845 -0.133 1495723 CBMicro_028345 O=C(Nc1sc2CCCCCCc2c1C#N)C3CC4CCC3C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J08 compound treatment 0.341 0.00465 0.39 0.341 3.0E-4 0.03 0.2915 0.7541 1939865 CBMicro_028346 OC(=O)CNC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J09 compound treatment 0.34 0.00365 0.3 0.341 3.0E-4 0.03 0.2328 0.7663 1939866 CBMicro_028347 Cc1ccc(Cl)cc1NC(=O)c2cnccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J10 compound treatment 0.321 -0.0154 -1.27 0.314 -0.0267 -2.37 -2.5745 -0.9579 1939867 CBMicro_028348 ClC1=CCC2C(C1)C(=O)N(CCc3c[nH]c4ccccc34)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J11 compound treatment 0.332 -0.00435 -0.36 0.323 -0.0177 -1.57 -1.3648 -0.8479 1939868 CBMicro_028349 CC(=O)c1cccc(NC(=O)c2ccc3OCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J12 compound treatment 0.329 -0.00735 -0.61 0.33 -0.0107 -0.95 -1.1023 -0.9773 1635003 CBMicro_028350 NC(=O)c1c(NC(=O)C2(CC3CC4CC(C3)C2)C4)sc5CCCCCCc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J13 compound treatment 0.329 -0.00735 -0.61 0.328 -0.0127 -1.13 -1.2276 -0.9587 1120095 CBMicro_028351 CN1CCN(CC1)NC(=O)Nc2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J14 compound treatment 0.365 0.0286 2.38 0.359 0.0183 1.62 2.8283 0.9826 1325041 CBMicro_028352 CCOC(=O)c1c(C)c(sc1NC(=O)C(C)Oc2ccc(Cl)cc2Cl)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J15 compound treatment 0.326 -0.0104 -0.86 0.333 -0.0077 -0.68 -1.0904 -0.9935 1939869 CBMicro_028353 COc1ccccc1C(=O)N/N=C(\C)/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J16 compound treatment 0.351 0.0146 1.22 0.352 0.0113 1.0 1.5678 0.9954 1939870 CBMicro_028354 CCOc1ccccc1N2CCN(CC2)C(=O)c3cc(Cl)ccc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J17 compound treatment 0.362 0.0256 2.13 0.362 0.0213 1.89 2.8402 0.9982 1339008 CBMicro_028355 CCN(CC)c1ccc(NC(=O)c2ccncc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J18 compound treatment 0.336 -3.55E-4 -0.03 0.336 -0.0047 -0.42 -0.3154 -0.7552 1939871 CBMicro_028356 Fc1ccc(NC(=O)c2cnccn2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J19 compound treatment 0.334 -0.00235 -0.2 0.342 0.0013 0.12 -0.0568 -0.2502 1518771 CBMicro_028357 Cc1cc(C)nc(NC(=O)Nc2ccc(Cl)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J20 compound treatment 0.336 -3.55E-4 -0.03 0.34 -7.0E-4 -0.06 -0.0647 -0.9421 1565158 CBMicro_028358 Cc1onc(c1C(=O)Nc2sc(C)c(C)c2C#N)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J21 compound treatment 0.285 -0.0514 -4.26 0.301 -0.0397 -3.52 -5.5025 -0.9954 1939872 CBMicro_028359 CCOc1ccc(cc1)S(=O)(=O)NNc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J22 compound treatment 0.365 0.0286 2.38 0.366 0.0253 2.24 3.267 0.9996 1939873 CBMicro_028360 COc1ccc(/C=C/C(=O)NCc2ccc(C)cc2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J23 positive control 0.086 -0.25 -20.78 0.085 -0.256 -22.66 -30.7201 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 J24 positive control 0.091 -0.245 -20.37 0.091 -0.25 -22.13 -30.0506 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K01 mock treatment 0.331 -0.00535 -0.44 0.337 -0.0037 -0.33 -0.5462 -0.9888 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K02 mock treatment 0.338 0.00165 0.14 0.341 3.0E-4 0.03 0.1154 0.8292 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K03 compound treatment 0.321 -0.0154 -1.27 0.321 -0.0197 -1.75 -2.1359 -0.9881 1939874 CBMicro_028361 Cc1ccc(OCCn2c(S)nc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K04 compound treatment 0.335 -0.00135 -0.11 0.336 -0.0047 -0.42 -0.3741 -0.867 1939875 CBMicro_028362 O=C1CC(CC(=C2C(=O)CCCC2=O)N3CCCC3)CC(=O)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K05 compound treatment 0.33 -0.00635 -0.53 0.327 -0.0137 -1.21 -1.2316 -0.9303 1939876 CBMicro_028363 COC(C(=O)NNC(=O)COc1ccccc1OC)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K06 compound treatment 0.372 0.0356 2.96 0.379 0.0383 3.39 4.4926 0.9977 1939877 CBMicro_028364 Fc1ccc(cc1)C2C3(OC(c4ccc(Cl)cc4)C25C(=O)c6ccccc6C5=O)C(=O)c7ccccc7C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K07 compound treatment 0.354 0.0176 1.46 0.344 0.0033 0.29 1.2426 0.8319 1330468 CBMicro_028365 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)C3CCCO3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K08 compound treatment 0.324 -0.0124 -1.03 0.323 -0.0177 -1.57 -1.8344 -0.9788 1442896 CBMicro_028366 Cc1c(NCc2ccccc2)[nH]c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K09 compound treatment 0.372 0.0356 2.96 0.368 0.0273 2.42 3.8032 0.995 1362022 CBMicro_028367 CC(=O)Nc1ccc(cc1)N2Cc3ccccc3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K10 compound treatment 0.324 -0.0124 -1.03 0.321 -0.0197 -1.75 -1.9598 -0.9679 1939878 CBMicro_028368 O=C(NNC(=O)c1ccc2OCOc2c1)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K11 compound treatment 0.334 -0.00235 -0.2 0.328 -0.0127 -1.13 -0.9341 -0.8177 1939879 CBMicro_028369 CC(C)OC(=O)c1sc2cc(ccc2c1Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K12 compound treatment 0.326 -0.0104 -0.86 0.329 -0.0117 -1.04 -1.341 -0.9957 1702269 CBMicro_028370 CCOc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K13 compound treatment 0.346 0.00965 0.8 0.34 -7.0E-4 -0.06 0.5223 0.6504 1939880 CBMicro_028371 COc1ccc2nc(C)c(CCC(=O)C)c(Cl)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K14 compound treatment 0.335 -0.00135 -0.11 0.346 0.0053 0.47 0.2526 0.523 1407035 CBMicro_028372 CCCC1CCc2c(C(=O)N)c(NC(=O)C3c4ccccc4Oc5ccccc35)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K15 compound treatment 0.342 0.00565 0.47 0.335 -0.0057 -0.51 -0.0258 -0.0374 1939881 CBMicro_028373 C/C(=N/NC(=O)c1ccoc1C)/C2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K16 compound treatment 0.338 0.00165 0.14 0.334 -0.0067 -0.59 -0.3233 -0.5306 1939882 CBMicro_028374 COc1cccc(c1)c2nc(no2)c3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K17 compound treatment 0.336 -3.55E-4 -0.03 0.337 -0.0037 -0.33 -0.2527 -0.7675 1939883 CBMicro_028375 Fc1ccc(NC(=O)/C=C/c2ccc(F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K18 compound treatment 0.31 -0.0264 -2.19 0.322 -0.0187 -1.66 -2.719 -0.9906 1939884 CBMicro_028376 Cc1ccc(cc1[N+](=O)[O-])C(=O)N/N=C/c2c3ccccc3cc4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K19 compound treatment 0.327 -0.00935 -0.78 0.332 -0.0087 -0.77 -1.0943 -1.0 1939885 CBMicro_028377 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K20 compound treatment 0.319 -0.0174 -1.44 0.325 -0.0157 -1.39 -2.0026 -0.9998 1655554 CBMicro_028378 Clc1ccc(NC(=O)NCCN2CCOCC2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K21 compound treatment 0.332 -0.00435 -0.36 0.332 -0.0087 -0.77 -0.8008 -0.9404 1473199 CBMicro_028379 COc1cccc(c1)C(=O)Nc2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K22 compound treatment 0.347 0.0106 0.88 0.349 0.0083 0.74 1.145 0.9958 1153370 CBMicro_028380 O=C(NCCN1CCOCC1)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K23 positive control 0.088 -0.248 -20.62 0.087 -0.254 -22.48 -30.4774 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 K24 positive control 0.095 -0.241 -20.04 0.092 -0.249 -22.04 -29.7531 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L01 mock treatment 0.335 -0.00135 -0.11 0.339 -0.0017 -0.15 -0.1861 -0.9896 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L02 mock treatment 0.338 0.00165 0.14 0.342 0.0013 0.12 0.178 0.9964 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L03 compound treatment 0.344 0.00765 0.63 0.341 3.0E-4 0.03 0.4676 0.7361 1560652 CBMicro_028381 CCOC(=O)c1c(C)c(sc1NC(=O)c2c(C)onc2c3ccccc3)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L04 compound treatment 0.332 -0.00435 -0.36 0.332 -0.0087 -0.77 -0.8008 -0.9404 1253009 CBMicro_028382 O=C(Cc1cccc2ccccc12)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L05 compound treatment 0.328 -0.00835 -0.69 0.33 -0.0107 -0.95 -1.161 -0.9882 1264692 CBMicro_028383 Cc1ccc(o1)c2cc(C(=O)Nc3nccs3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L06 compound treatment 0.335 -0.00135 -0.11 0.328 -0.0127 -1.13 -0.8754 -0.7739 1939886 CBMicro_028384 CCn1c(SC)nc2sc3CCCCc3c2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L07 compound treatment 0.327 -0.00935 -0.78 0.325 -0.0157 -1.39 -1.533 -0.9621 1162900 CBMicro_028385 Fc1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L08 compound treatment 0.36 0.0236 1.96 0.356 0.0153 1.36 2.3468 0.9837 1939887 CBMicro_028386 COc1ccc2nc(C)c(C/C=C(/C)\Cl)c(S)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L09 compound treatment 0.34 0.00365 0.3 0.339 -0.0017 -0.15 0.1075 0.3179 1939888 CBMicro_028387 COC(=O)c1sc(NC(=O)c2ccc(Br)o2)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L10 compound treatment 0.356 0.0196 1.63 0.354 0.0133 1.18 1.9867 0.9873 1939889 CBMicro_028388 CCCCSCc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L11 compound treatment 0.379 0.0426 3.54 0.371 0.0303 2.69 4.4022 0.9907 1939890 CBMicro_028389 CCOC(=O)c1ccc(NC(=O)/C=C/c2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L12 compound treatment 0.358 0.0216 1.8 0.373 0.0323 2.86 3.2947 0.9748 1661735 CBMicro_028390 Clc1cccc(c1)N2CCN(CC2)C(=O)C3c4ccccc4Oc5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L13 compound treatment 0.357 0.0206 1.71 0.354 0.0133 1.18 2.0454 0.9833 1307247 CBMicro_028391 CCOc1ccc(cc1)c2cc(C(=O)Nc3ccncc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L14 compound treatment 0.349 0.0126 1.05 0.348 0.0073 0.65 1.1998 0.973 1188946 CBMicro_028392 CC(C)CNC(=O)c1cc(nc2ccccc12)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L15 compound treatment 0.345 0.00865 0.72 0.347 0.0063 0.56 0.9023 0.9923 1183949 CBMicro_028393 COc1ccc(cc1OC)c2cc(C(=O)N3CCCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L16 compound treatment 0.329 -0.00735 -0.61 0.328 -0.0127 -1.13 -1.2276 -0.9587 1448664 CBMicro_028394 CC(=O)NS(=O)(=O)c1ccc(NC(=O)CCC2CCCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L17 compound treatment 0.358 0.0216 1.8 0.35 0.0093 0.82 1.8534 0.9375 1410926 CBMicro_028395 CCOC(=O)c1c(NC(=O)C2C(C3CC2C=C3)C(=O)O)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L18 compound treatment 0.349 0.0126 1.05 0.335 -0.0057 -0.51 0.3851 0.3306 1851720 CBMicro_028396 Cc1csc(NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L19 compound treatment 0.329 -0.00735 -0.61 0.334 -0.0067 -0.59 -0.8516 -0.9999 1597923 CBMicro_028397 CCC(C(=O)Nc1cc(OC)c(Cl)cc1OC)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L20 compound treatment 0.372 0.0356 2.96 0.378 0.0373 3.31 4.4299 0.9985 1939891 CBMicro_028398 Clc1ccc(/C=C/C(=O)Nc2ccc3OCOc3c2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L21 compound treatment 0.34 0.00365 0.3 0.341 3.0E-4 0.03 0.2328 0.7663 1939892 CBMicro_028399 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CC)c3ccc(OCC)cc23)S1)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L22 compound treatment 0.333 -0.00335 -0.28 0.334 -0.0067 -0.59 -0.6168 -0.9405 1939893 CBMicro_028400 COc1cc(cc(OC)c1OC)C(=O)NN=C2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L23 positive control 0.087 -0.249 -20.7 0.088 -0.253 -22.39 -30.4734 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 L24 positive control 0.093 -0.243 -20.2 0.092 -0.249 -22.04 -29.8705 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M01 mock treatment 0.339 0.00265 0.22 0.337 -0.0037 -0.33 -0.0766 -0.1941 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M02 mock treatment 0.336 -3.55E-4 -0.03 0.339 -0.0017 -0.15 -0.1274 -0.8297 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M03 compound treatment 0.321 -0.0154 -1.27 0.319 -0.0217 -1.92 -2.2612 -0.9801 1173943 CBMicro_028401 CCOc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M04 compound treatment 0.341 0.00465 0.39 0.34 -7.0E-4 -0.06 0.2288 0.5858 1221917 CBMicro_028402 COc1ccc(OCC(=O)N2CCN(CC2)c3ccccn3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M05 compound treatment 0.323 -0.0134 -1.11 0.321 -0.0197 -1.75 -2.0185 -0.976 1437651 CBMicro_028403 CCc1c(C)sc(NC(=O)c2c(C)onc2c3ccccc3Cl)c1C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M06 compound treatment 0.336 -3.55E-4 -0.03 0.334 -0.0067 -0.59 -0.4407 -0.7413 1939894 CBMicro_028404 COc1ccc(CCNC(=O)c2ccccc2[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M07 compound treatment 0.326 -0.0104 -0.86 0.326 -0.0147 -1.3 -1.529 -0.9796 1939895 CBMicro_028405 COc1ccc(NC(=O)c2sc3cc(C)ccc3c2Cl)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M08 compound treatment 0.374 0.0376 3.13 0.359 0.0183 1.62 3.3567 0.9533 1939896 CBMicro_028406 Cc1ccsc1/C=C(/C#N)\c2nc(cs2)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M09 compound treatment 0.344 0.00765 0.63 0.337 -0.0037 -0.33 0.2169 0.3037 1781760 CBMicro_028407 [O-][N+](=O)c1cccc(c1)C2NC(=O)c3sc(=S)n(c3N2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M10 compound treatment 0.322 -0.0144 -1.19 0.32 -0.0207 -1.83 -2.1398 -0.9782 1408679 CBMicro_028408 COc1ccc(CCC(=O)Nc2cc(Cl)ccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M11 compound treatment 0.328 -0.00835 -0.69 0.33 -0.0107 -0.95 -1.161 -0.9882 1939897 CBMicro_028409 Fc1ccc(cc1)C(=O)NCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M12 compound treatment 0.343 0.00665 0.55 0.343 0.0023 0.2 0.5342 0.9083 1129065 CBMicro_028410 COc1ccc(cc1OC)c2cc(C(=O)N3CCN(C)CC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M13 compound treatment 0.338 0.00165 0.14 0.336 -0.0047 -0.42 -0.1979 -0.4516 1602579 CBMicro_028411 COc1ccc(OCC(=O)NCCc2ccc(OC)c(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M14 compound treatment 0.333 -0.00335 -0.28 0.329 -0.0117 -1.04 -0.9301 -0.8663 1158951 CBMicro_028412 CCC(Oc1ccccc1)C(=O)Nc2cc(C)ccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M15 compound treatment 0.35 0.0136 1.13 0.347 0.0063 0.56 1.1958 0.9469 1939898 CBMicro_028413 c1ccc(cc1)c2noc(n2)c3ccc4ccccc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M16 compound treatment 0.336 -3.55E-4 -0.03 0.333 -0.0077 -0.68 -0.5034 -0.7369 1221938 CBMicro_028414 COC(=O)c1ccc(C(=O)OC)c(NC(=O)Nc2ccc(Cl)c(Cl)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M17 compound treatment 0.33 -0.00635 -0.53 0.331 -0.0097 -0.86 -0.9809 -0.9725 1939899 CBMicro_028415 OC(=O)CC/C(=N/NC(=O)c1c[nH]c2ccccc12)/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M18 compound treatment 0.343 0.00665 0.55 0.339 -0.0017 -0.15 0.2836 0.4958 1210643 CBMicro_028416 O=C(Nc1nc2ccccc2[nH]1)C3CC3c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M19 compound treatment 0.352 0.0156 1.3 0.356 0.0153 1.36 1.8772 0.9998 1939900 CBMicro_028417 Nc1cccc(c1)C(=O)/C=C/c2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M20 compound treatment 0.342 0.00565 0.47 0.341 3.0E-4 0.03 0.3502 0.746 1480400 CBMicro_028418 COC(=O)c1sc(NC(=O)C2CC3CCC2C3)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M21 compound treatment 0.36 0.0236 1.96 0.348 0.0073 0.65 1.8455 0.8929 1409484 CBMicro_028419 CCOc1cc(cc(OCC)c1OCC)c2nnc(o2)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M22 compound treatment 0.333 -0.00335 -0.28 0.33 -0.0107 -0.95 -0.8675 -0.8777 1551037 CBMicro_028420 CCN(CC)C(=O)c1sc(NC(=O)c2cccc(F)c2)c(C(=O)OC(C)C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M23 positive control 0.087 -0.249 -20.7 0.088 -0.253 -22.39 -30.4734 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 M24 positive control 0.092 -0.244 -20.29 0.092 -0.249 -22.04 -29.9292 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N01 mock treatment 0.344 0.00765 0.63 0.344 0.0033 0.29 0.6556 0.9381 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N02 mock treatment 0.343 0.00665 0.55 0.347 0.0063 0.56 0.7849 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N03 compound treatment 0.332 -0.00435 -0.36 0.332 -0.0087 -0.77 -0.8008 -0.9404 1729248 CBMicro_028421 COc1ccc(cc1)C(=O)Nc2sc3CC(CCc3c2C(=O)N)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N04 compound treatment 0.328 -0.00835 -0.69 0.327 -0.0137 -1.21 -1.349 -0.9647 1939901 CBMicro_028422 Cc1ccc(/C=N/N=C(c2ccccc2)c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N05 compound treatment 0.334 -0.00235 -0.2 0.333 -0.0077 -0.68 -0.6208 -0.8745 1939902 CBMicro_028423 CCOC(=O)c1sc(NC(=O)c2ccc(Cl)cc2Cl)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N06 compound treatment 0.346 0.00965 0.8 0.344 0.0033 0.29 0.773 0.9068 1393977 CBMicro_028424 O=C(NCC1(CCCC1)c2ccccc2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N07 compound treatment 0.439 0.103 8.52 0.343 0.0023 0.2 6.1697 0.7238 1634362 CBMicro_028425 CCCOC(=O)c1c(NC(=O)c2cnccn2)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N08 compound treatment 0.335 -0.00135 -0.11 0.333 -0.0077 -0.68 -0.5621 -0.8127 1939903 CBMicro_028426 CCCc1cnc(nc1)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N09 compound treatment 0.36 0.0236 1.96 0.373 0.0323 2.86 3.4121 0.9831 1423356 CBMicro_028427 COc1ccc(cc1OC)n2sc3c(-c4ccccc4NC3(C)C)c2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N10 compound treatment 0.334 -0.00235 -0.2 0.332 -0.0087 -0.77 -0.6834 -0.8592 1291223 CBMicro_028428 CC1(C)CC(Cc2ccccc2)(CCO1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N11 compound treatment 0.35 0.0136 1.13 0.35 0.0093 0.82 1.3838 0.9878 1534704 CBMicro_028429 NS(=O)(=O)c1ccc(NC(=O)CCC2CCCCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N12 compound treatment 0.377 0.0406 3.37 0.359 0.0183 1.62 3.5328 0.9436 1596362 CBMicro_028430 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccc(OC)cc4OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N13 compound treatment 0.349 0.0126 1.05 0.348 0.0073 0.65 1.1998 0.973 1939904 CBMicro_028431 Cc1onc(c1C(=O)Nc2cc(ccc2C)[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N14 compound treatment 0.353 0.0166 1.38 0.357 0.0163 1.44 1.9986 0.9998 1235569 CBMicro_028432 CCN(CC)C(=O)c1sc(NC(=O)c2ccco2)c(C(=O)OC(C)C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N15 compound treatment 0.399 0.0626 5.2 0.39 0.0493 4.37 6.7669 0.9962 1240984 CBMicro_028433 COc1ccc(cc1)c2cc(C(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)C)c5ccccc5n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N16 compound treatment 0.365 0.0286 2.38 0.364 0.0233 2.06 3.1417 0.9975 1642068 CBMicro_028434 Brc1cccc(c1)c2cc(C(=O)N3CCCCCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N17 compound treatment 0.345 0.00865 0.72 0.335 -0.0057 -0.51 0.1503 0.1713 1396660 CBMicro_028435 COc1cc(cc(OC)c1OC)C(=O)Nc2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N18 compound treatment 0.331 -0.00535 -0.44 0.332 -0.0087 -0.77 -0.8595 -0.9658 1662202 CBMicro_028436 Cc1occc1C(=O)Nc2ccc(F)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N19 compound treatment 0.346 0.00965 0.8 0.347 0.0063 0.56 0.961 0.9845 1483606 CBMicro_028437 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N20 compound treatment 0.351 0.0146 1.22 0.35 0.0093 0.82 1.4425 0.9821 1555914 CBMicro_028438 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3cccc(C)c3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N21 compound treatment 0.344 0.00765 0.63 0.343 0.0023 0.2 0.5929 0.8895 1939905 CBMicro_028439 O=C(NCCN1CCOCC1)/C=C/c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N22 compound treatment 0.339 0.00265 0.22 0.336 -0.0047 -0.42 -0.1392 -0.2957 1218483 CBMicro_028440 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3c(Cl)cccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N23 positive control 0.088 -0.248 -20.62 0.087 -0.254 -22.48 -30.4774 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 N24 positive control 0.092 -0.244 -20.29 0.092 -0.249 -22.04 -29.9292 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O01 mock treatment 0.341 0.00465 0.39 0.344 0.0033 0.29 0.4795 0.9907 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O02 mock treatment 0.342 0.00565 0.47 0.344 0.0033 0.29 0.5382 0.9742 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O03 compound treatment 0.334 -0.00235 -0.2 0.332 -0.0087 -0.77 -0.6834 -0.8592 1939906 CBMicro_028441 COc1cc(cc(OC)c1OC)C(=O)N/N=C/c2ccsc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O04 compound treatment 0.339 0.00265 0.22 0.335 -0.0057 -0.51 -0.2019 -0.3666 1008333 CBMicro_028442 Nc1ccc(Oc2ccc(N)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O05 compound treatment 0.333 -0.00335 -0.28 0.332 -0.0087 -0.77 -0.7421 -0.9053 1561043 CBMicro_028443 Cc1nnc(NC(=O)C(Sc2ccccc2)c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O06 compound treatment 0.326 -0.0104 -0.86 0.326 -0.0147 -1.3 -1.529 -0.9796 1662026 CBMicro_028444 Clc1ccc(NC(=O)Nc2ncccc2Cl)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O07 compound treatment 0.333 -0.00335 -0.28 0.33 -0.0107 -0.95 -0.8675 -0.8777 1529253 CBMicro_028445 Cc1ccc(cc1NC(=O)c2ccc(Br)o2)c3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O08 compound treatment 0.333 -0.00335 -0.28 0.333 -0.0077 -0.68 -0.6795 -0.9219 1939907 CBMicro_028446 O=C(Nc1nnc(CCSCCc2nnc(NC(=O)c3ccco3)s2)s1)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O09 compound treatment 0.338 0.00165 0.14 0.338 -0.0027 -0.24 -0.0726 -0.2636 1939908 CBMicro_028447 COc1ccc(cc1)c2noc(n2)c3cccc(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O10 compound treatment 0.338 0.00165 0.14 0.336 -0.0047 -0.42 -0.1979 -0.4516 1387349 CBMicro_028448 COc1ccc(Cl)cc1C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O11 compound treatment 0.367 0.0306 2.54 0.372 0.0313 2.77 3.7604 0.9991 1913067 CBMicro_028449 O=C(CSc1nc2ccccc2s1)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O12 compound treatment 0.349 0.0126 1.05 0.349 0.0083 0.74 1.2624 0.9849 1221475 CBMicro_028450 COc1ccc(cc1OC)C(=O)Nc2cc(C)cc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O13 compound treatment 0.333 -0.00335 -0.28 0.333 -0.0077 -0.68 -0.6795 -0.9219 1939909 CBMicro_028451 [O-][N+](=O)c1cccc(c1)c2noc(n2)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O14 compound treatment 0.365 0.0286 2.38 0.363 0.0223 1.98 3.079 0.9958 1939910 CBMicro_028452 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)/C=C/C(=O)O)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O15 compound treatment 0.329 -0.00735 -0.61 0.326 -0.0147 -1.3 -1.3529 -0.9404 1939911 CBMicro_028453 CC(C)N1CCC(=NNC(=O)C(O)c2ccccc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O16 compound treatment 0.358 0.0216 1.8 0.355 0.0143 1.27 2.1668 0.9854 1939912 CBMicro_028454 Cc1onc(c1C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O17 compound treatment 0.333 -0.00335 -0.28 0.333 -0.0077 -0.68 -0.6795 -0.9219 1939913 CBMicro_028455 CC(=O)Nc1ccc(OCC=C(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O18 compound treatment 0.339 0.00265 0.22 0.338 -0.0027 -0.24 -0.0139 -0.0428 1939914 CBMicro_028456 FC(F)(F)C(=O)Nc1ccc(Cc2ccc(NC(=O)C(F)(F)F)c(Cl)c2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O19 compound treatment 0.33 -0.00635 -0.53 0.329 -0.0117 -1.04 -1.1062 -0.9509 1477090 CBMicro_028457 COc1cccc(c1)c2nc(no2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O20 compound treatment 0.339 0.00265 0.22 0.338 -0.0027 -0.24 -0.0139 -0.0428 1656939 CBMicro_028458 Cc1onc(c1C(=O)Nc2sc(C)c(C)c2C(=O)N)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O21 compound treatment 0.333 -0.00335 -0.28 0.331 -0.0097 -0.86 -0.8048 -0.8906 1939915 CBMicro_028459 COc1ccc(cc1)c2nc(no2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O22 compound treatment 0.346 0.00965 0.8 0.346 0.0053 0.47 0.8983 0.9677 1154265 CBMicro_028460 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O23 positive control 0.089 -0.247 -20.54 0.086 -0.255 -22.57 -30.4813 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 O24 positive control 0.093 -0.243 -20.2 0.092 -0.249 -22.04 -29.8705 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P01 mock treatment 0.344 0.00765 0.63 0.343 0.0023 0.2 0.5929 0.8895 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P02 mock treatment 0.345 0.00865 0.72 0.346 0.0053 0.47 0.8396 0.9789 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P03 compound treatment 0.343 0.00665 0.55 0.354 0.0133 1.18 1.2235 0.9402 1939916 CBMicro_028461 Clc1ccc(Cl)c(c1)C(=O)NCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P04 compound treatment 0.334 -0.00235 -0.2 0.334 -0.0067 -0.59 -0.5581 -0.8928 1632451 CBMicro_028462 CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P05 compound treatment 0.342 0.00565 0.47 0.338 -0.0027 -0.24 0.1622 0.3082 1151391 CBMicro_028463 O=C(CC(c1ccccc1)c2ccccc2)NCc3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P06 compound treatment 0.321 -0.0154 -1.27 0.324 -0.0167 -1.48 -1.9479 -0.9972 1317884 CBMicro_028464 CCSc1nc(SCC)c2c3CCN(C)Cc3sc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P07 compound treatment 0.327 -0.00935 -0.78 0.329 -0.0117 -1.04 -1.2823 -0.9899 1939917 CBMicro_028465 COc1ccc(cc1)C(=O)Nc2ccc(cn2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P08 compound treatment 0.332 -0.00435 -0.36 0.333 -0.0077 -0.68 -0.7382 -0.9559 1713499 CBMicro_028466 Cc1ccnc(NC(=O)C2CCCCC2C(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P09 compound treatment 0.385 0.0486 4.04 0.385 0.0443 3.93 5.6317 0.9999 1939918 CBMicro_028467 OC(=O)C1CCCCC1C(=O)Nc2nc(cs2)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P10 compound treatment 0.382 0.0456 3.79 0.385 0.0443 3.93 5.4556 0.9998 1210928 CBMicro_028468 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P11 compound treatment 0.359 0.0226 1.88 0.363 0.0223 1.98 2.7268 0.9997 1568792 CBMicro_028469 CCOC(=O)c1sc(NC(=O)c2ccc(cc2)C(C)C)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P12 compound treatment 0.334 -0.00235 -0.2 0.329 -0.0117 -1.04 -0.8714 -0.8259 1724038 CBMicro_028470 O=C(CC(c1ccccc1)c2ccccc2)Nc3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P13 compound treatment 0.343 0.00665 0.55 0.346 0.0053 0.47 0.7222 0.9968 1395585 CBMicro_028471 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P14 compound treatment 0.331 -0.00535 -0.44 0.333 -0.0077 -0.68 -0.7969 -0.9784 1619230 CBMicro_028472 CCC1CCc2c(C(=O)N)c(NC(=O)Nc3ccccc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P15 compound treatment 0.345 0.00865 0.72 0.351 0.0103 0.91 1.1529 0.9929 1584049 CBMicro_028473 Cc1ccc(c2csc(NC(=O)C3CCCCC3C(=O)O)n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P16 compound treatment 0.334 -0.00235 -0.2 0.337 -0.0037 -0.33 -0.3701 -0.9695 1698689 CBMicro_028474 Cc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(Br)cc4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P17 compound treatment 0.33 -0.00635 -0.53 0.326 -0.0147 -1.3 -1.2942 -0.9208 1174509 CBMicro_028475 Cc1sc(NC(=O)C2CC2c3ccccc3)nc1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P18 compound treatment 0.355 0.0186 1.55 0.352 0.0113 1.0 1.8026 0.9778 1939919 CBMicro_028476 C/C(=N/NC(=O)c1ccoc1C)/c2cccc(NC(=O)c3ccc(Cl)cc3Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P19 compound treatment 0.341 0.00465 0.39 0.341 3.0E-4 0.03 0.2915 0.7541 1141862 CBMicro_028477 Clc1cccc(c1)N2CCN(CC2)C(=O)C3CCCO3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P20 compound treatment 0.343 0.00665 0.55 0.341 3.0E-4 0.03 0.4089 0.7403 1939920 CBMicro_028478 CCOC(=O)c1c(NC(=O)C2CC=CCC2C(=O)O)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P21 compound treatment 0.335 -0.00135 -0.11 0.33 -0.0107 -0.95 -0.7501 -0.7855 1207203 CBMicro_028479 COc1ccc(C)cc1NC(=O)C2CC2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P22 compound treatment 0.343 0.00665 0.55 0.329 -0.0117 -1.04 -0.3431 -0.2921 1939921 CBMicro_028480 CC(C)OC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(C)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P23 positive control 0.09 -0.246 -20.45 0.088 -0.253 -22.39 -30.2973 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.774 P24 positive control 0.094 -0.242 -20.12 0.094 -0.247 -21.86 -29.6865 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A01 mock treatment 0.322 -0.0208 -1.73 0.325 -0.0188 -1.66 -2.397 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A02 mock treatment 0.33 -0.0128 -1.06 0.337 -0.00677 -0.6 -1.1754 -0.9633 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A03 compound treatment 0.319 -0.0238 -1.98 0.324 -0.0198 -1.75 -2.6358 -0.9982 1669092 CBMicro_028481 CCOC(=O)c1c(NC(=O)C2CC2c3ccccc3)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A04 compound treatment 0.32 -0.0228 -1.89 0.327 -0.0168 -1.49 -2.3891 -0.9928 1355471 CBMicro_028482 CCc1nnc(NC(=O)CCc2ccc(OC)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A05 compound treatment 0.326 -0.0168 -1.39 0.332 -0.0118 -1.04 -1.7236 -0.9897 1739714 CBMicro_028483 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A06 compound treatment 0.335 -0.0078 -0.65 0.334 -0.00977 -0.87 -1.0699 -0.9898 1578721 CBMicro_028484 CCN(CC)C(=O)c1sc(NC(=O)c2ccc(Cl)cc2)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A07 compound treatment 0.338 -0.0048 -0.4 0.335 -0.00877 -0.78 -0.8311 -0.9519 1523258 CBMicro_028485 Cc1sc(NC(=O)CCC2CCCCC2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A08 compound treatment 0.317 -0.0258 -2.14 0.32 -0.0238 -2.11 -3.0039 -1.0 1939922 CBMicro_028486 COc1cccc(OCc2nc(no2)c3ccccn3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A09 compound treatment 0.313 -0.0298 -2.47 0.318 -0.0258 -2.28 -3.364 -0.9992 1480280 CBMicro_028487 Clc1cccc(Cl)c1C(=O)NCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A10 compound treatment 0.336 -0.0068 -0.56 0.335 -0.00877 -0.78 -0.9485 -0.9877 1138351 CBMicro_028488 CC(C)CNC(=O)c1cc(nc2ccccc12)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A11 compound treatment 0.323 -0.0198 -1.64 0.328 -0.0158 -1.4 -2.1503 -0.9967 1459173 CBMicro_028489 Fc1ccc(cc1)N2CCN(CC2)C(=O)C3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A12 compound treatment 0.333 -0.0098 -0.81 0.337 -0.00677 -0.6 -0.9993 -0.9887 1145971 CBMicro_028490 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)C3CC4CCC3C4)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A13 compound treatment 0.326 -0.0168 -1.39 0.326 -0.0178 -1.57 -2.0996 -0.9982 1939923 CBMicro_028491 O=C(COc1ccccc1)NCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A14 compound treatment 0.347 0.0042 0.35 0.343 -7.67E-4 -0.07 0.1985 0.5588 1939924 CBMicro_028492 COC(=O)c1sc(NC(=O)c2sc3cc(C)ccc3c2Cl)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A15 compound treatment 0.327 -0.0158 -1.31 0.333 -0.0108 -0.95 -1.6022 -0.9878 1372165 CBMicro_028493 CCc1ccc(cc1)c2cc(C(=O)N3CCN(CC3)c4cccc(Cl)c4)c5ccccc5n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A16 compound treatment 0.32 -0.0228 -1.89 0.331 -0.0128 -1.13 -2.1385 -0.9697 1531587 CBMicro_028494 Brc1cccc(NC(=O)c2cnccn2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A17 compound treatment 0.323 -0.0198 -1.64 0.33 -0.0138 -1.22 -2.025 -0.9892 1939925 CBMicro_028495 OC(=O)CC/C(=N\NS(=O)(=O)c1ccccc1)/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A18 compound treatment 0.321 -0.0218 -1.81 0.334 -0.00977 -0.87 -1.8918 -0.943 1337874 CBMicro_028496 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A19 compound treatment 0.338 -0.0048 -0.4 0.334 -0.00977 -0.87 -0.8938 -0.938 1203701 CBMicro_028497 CCOC(=O)c1c(C)c(sc1NC(=O)C(CC)Oc2ccccc2)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A20 compound treatment 0.322 -0.0208 -1.73 0.328 -0.0158 -1.4 -2.209 -0.9945 1939926 CBMicro_028498 COc1cccc(/C=N/N=C(\N)/c2nonc2N)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A21 compound treatment 0.322 -0.0208 -1.73 0.328 -0.0158 -1.4 -2.209 -0.9945 1939927 CBMicro_028499 CCOC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2C)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A22 compound treatment 0.322 -0.0208 -1.73 0.327 -0.0168 -1.49 -2.2717 -0.9972 1170194 CBMicro_028500 CC1(C)N(O)C(N(O)C1(C)C)c2ccc[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A23 positive control 0.083 -0.26 -21.57 0.085 -0.259 -22.93 -31.4668 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 A24 positive control 0.086 -0.257 -21.32 0.087 -0.257 -22.76 -31.1653 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B01 mock treatment 0.331 -0.0118 -0.98 0.333 -0.0108 -0.95 -1.3674 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B02 mock treatment 0.345 0.0022 0.18 0.347 0.00323 0.29 0.3318 0.9763 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B03 compound treatment 0.329 -0.0138 -1.15 0.336 -0.00777 -0.69 -1.2968 -0.9703 1710407 CBMicro_028501 CCOc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B04 compound treatment 0.412 0.0692 5.74 0.407 0.0632 5.6 8.0248 0.9999 1703746 CBMicro_028502 CCOc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B05 compound treatment 0.318 -0.0248 -2.06 0.328 -0.0158 -1.4 -2.4439 -0.9822 1603305 CBMicro_028503 OC(CN1CCNCC1)Cn2c3ccccc3c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B06 compound treatment 0.326 -0.0168 -1.39 0.333 -0.0108 -0.95 -1.6609 -0.9829 1939928 CBMicro_028504 C/C(=N\NC(=O)Cc1ccc(cc1)[N+](=O)[O-])/c2ccc(Br)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B07 compound treatment 0.327 -0.0158 -1.31 0.333 -0.0108 -0.95 -1.6022 -0.9878 1939929 CBMicro_028505 Clc1ccc(cc1)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B08 compound treatment 0.334 -0.0088 -0.73 0.336 -0.00777 -0.69 -1.0033 -0.9996 1640676 CBMicro_028506 CC(C)CNC(=O)c1c(C)onc1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B09 compound treatment 0.303 -0.0398 -3.3 0.31 -0.0338 -2.99 -4.4524 -0.9988 1939930 CBMicro_028507 CCc1ccc(cc1)S(=O)(=O)NNc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B10 compound treatment 0.343 2.0E-4 0.02 0.356 0.0122 1.08 0.7783 0.7179 1939931 CBMicro_028508 COc1cccc(c1)C(=O)N/N=C(/C)\c2cccc(NC(=O)c3ccc(Cl)cc3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B11 compound treatment 0.31 -0.0328 -2.72 0.326 -0.0178 -1.57 -3.0388 -0.9661 1939932 CBMicro_028509 [O-][N+](=O)c1cccc(c1)S(=O)(=O)/N=C/2\C=CC(=O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B12 compound treatment 0.366 0.0232 1.93 0.373 0.0292 2.59 3.1938 0.9893 1939933 CBMicro_028510 CCOc1ccc(NC(=O)c2cc(OCC)c(OCC)c(OCC)c2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B13 compound treatment 0.354 0.0112 0.93 0.355 0.0112 1.0 1.3614 0.9994 1277385 CBMicro_028511 CCCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B14 compound treatment 0.339 -0.0038 -0.32 0.343 -7.67E-4 -0.07 -0.2711 -0.8401 1591794 CBMicro_028512 CCOC(=O)c1sc(NC(=O)c2ccc(Br)o2)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B15 compound treatment 0.332 -0.0108 -0.9 0.336 -0.00777 -0.69 -1.1207 -0.9915 1597312 CBMicro_028513 Clc1cccnc1NC(=O)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B16 compound treatment 0.33 -0.0128 -1.06 0.34 -0.00377 -0.33 -0.9874 -0.8865 1428936 CBMicro_028514 COC(=O)c1sccc1NC(=O)c2sc3ccccc3c2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B17 compound treatment 0.327 -0.0158 -1.31 0.341 -0.00277 -0.25 -1.1009 -0.825 1345285 CBMicro_028515 CC(NC(=O)Nc1ccc(Cl)c(Cl)c1)C2CC3CCC2C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B18 compound treatment 0.341 -0.0018 -0.15 0.34 -0.00377 -0.33 -0.3417 -0.9343 1872639 CBMicro_028516 CCc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6cccc(Cl)c6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B19 compound treatment 0.33 -0.0128 -1.06 0.337 -0.00677 -0.6 -1.1754 -0.9633 1448488 CBMicro_028517 CCOC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B20 compound treatment 0.327 -0.0158 -1.31 0.337 -0.00677 -0.6 -1.3515 -0.9371 1284011 CBMicro_028518 Brc1cccc(c1)c2cc(C(=O)Nc3nncs3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B21 compound treatment 0.344 0.0012 0.1 0.341 -0.00277 -0.25 -0.1029 -0.3889 1534114 CBMicro_028519 COc1ccc(cc1OC)C(=O)NCCc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B22 compound treatment 0.284 -0.0588 -4.88 0.289 -0.0548 -4.85 -6.8837 -1.0 1348536 CBMicro_028520 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cc(nc4ccccc34)c5ccccc5Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B23 positive control 0.087 -0.256 -21.24 0.084 -0.26 -23.02 -31.2946 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 B24 positive control 0.091 -0.252 -20.9 0.092 -0.252 -22.31 -30.5585 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C01 mock treatment 0.342 -8.0E-4 -0.07 0.34 -0.00377 -0.33 -0.283 -0.8315 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C02 mock treatment 0.348 0.0052 0.43 0.351 0.00723 0.64 0.7585 0.9815 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C03 compound treatment 0.329 -0.0138 -1.15 0.337 -0.00677 -0.6 -1.2341 -0.9544 1939934 CBMicro_028521 Cc1ccc(cc1NC(=O)Cc2ccccc2)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C04 compound treatment 0.361 0.0182 1.51 0.363 0.0192 1.7 2.2737 0.9982 1341319 CBMicro_028522 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3cccnc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C05 compound treatment 0.306 -0.0368 -3.06 0.314 -0.0298 -2.64 -4.0256 -0.9973 1242932 CBMicro_028523 Cc1onc(c1C(=O)Nc2ccc(cc2)C(=O)N)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C06 compound treatment 0.344 0.0012 0.1 0.355 0.0112 1.0 0.7744 0.774 1208957 CBMicro_028524 Cc1sc(NC(=O)C2CC2c3ccccc3)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C07 compound treatment 0.35 0.0072 0.6 0.343 -7.67E-4 -0.07 0.3746 0.6227 1481503 CBMicro_028525 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C08 compound treatment 0.327 -0.0158 -1.31 0.333 -0.0108 -0.95 -1.6022 -0.9878 1071747 CBMicro_028526 OC(=O)C(CC(=O)c1ccccc1)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C09 compound treatment 0.342 -8.0E-4 -0.07 0.341 -0.00277 -0.25 -0.2203 -0.8674 1736880 CBMicro_028527 Brc1ccc(cc1)c2cc(C(=O)NCCN3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C10 compound treatment 0.334 -0.0088 -0.73 0.341 -0.00277 -0.25 -0.69 -0.8953 1241584 CBMicro_028528 CCOC(=O)c1c(NC(=O)c2ccoc2C)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C11 compound treatment 0.36 0.0172 1.43 0.368 0.0242 2.15 2.5283 0.9803 1939935 CBMicro_028529 Cc1sc(NC(=O)c2cc(Cl)ccc2Cl)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C12 compound treatment 0.343 2.0E-4 0.02 0.344 2.33E-4 0.02 0.0264 0.9941 1939936 CBMicro_028530 CCN(CC)C(=O)c1sc(NC(=O)/C=C/C(=O)O)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C13 compound treatment 0.342 -8.0E-4 -0.07 0.344 2.33E-4 0.02 -0.0323 -0.4649 1166995 CBMicro_028531 O=C(C1CCCO1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C14 compound treatment 0.334 -0.0088 -0.73 0.341 -0.00277 -0.25 -0.69 -0.8953 1173707 CBMicro_028532 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3nccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C15 compound treatment 0.387 0.0442 3.67 0.394 0.0502 4.45 5.7426 0.9954 1939937 CBMicro_028533 CC(C)c1ccc(/C=C/C(=O)Nc2ccc(cc2)C(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C16 compound treatment 0.371 0.0282 2.34 0.383 0.0392 3.48 4.114 0.9815 1143242 CBMicro_028534 Cc1ccc(o1)C(=O)Nc2sc3CCCCCCc3c2C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C17 compound treatment 0.345 0.0022 0.18 0.346 0.00223 0.2 0.2691 0.9992 1458704 CBMicro_028535 Cc1onc(c1C(=O)N2CCN(CC2)c3ccc(Cl)cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C18 compound treatment 0.349 0.0062 0.51 0.364 0.0202 1.79 1.6319 0.8748 1939938 CBMicro_028536 COc1ccc(CCNC(=O)/C=C/c2ccc(cc2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C19 compound treatment 0.324 -0.0188 -1.56 0.333 -0.0108 -0.95 -1.7783 -0.9721 1228647 CBMicro_028537 Cc1sc(NC(=O)NC2CCCCC2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C20 compound treatment 0.335 -0.0078 -0.65 0.341 -0.00277 -0.25 -0.6313 -0.9117 1939939 CBMicro_028538 COc1ccc(cc1)N2C(=O)/C(=C/c3cc4OCOc4cc3Br)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C21 compound treatment 0.339 -0.0038 -0.32 0.342 -0.00177 -0.16 -0.3338 -0.9477 1738625 CBMicro_028539 COC(=O)c1sc(NC(=O)c2c(C)onc2c3ccccc3)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C22 compound treatment 0.335 -0.0078 -0.65 0.341 -0.00277 -0.25 -0.6313 -0.9117 1939940 CBMicro_028540 Cc1ccccc1NCC(=O)N/N=C\c2cc(cc(Br)c2O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C23 positive control 0.146 -0.197 -16.34 0.134 -0.21 -18.59 -24.6979 -0.9979 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 C24 positive control 0.089 -0.254 -21.07 0.09 -0.254 -22.49 -30.8012 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D01 mock treatment 0.344 0.0012 0.1 0.347 0.00323 0.29 0.2731 0.9001 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D02 mock treatment 0.346 0.0032 0.27 0.343 -7.67E-4 -0.07 0.1398 0.5099 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D03 compound treatment 0.332 -0.0108 -0.9 0.337 -0.00677 -0.6 -1.058 -0.9809 1641205 CBMicro_028541 CC(=O)Nc1ccc(NS(=O)(=O)c2c(C)cc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D04 compound treatment 0.331 -0.0118 -0.98 0.34 -0.00377 -0.33 -0.9287 -0.8974 1346493 CBMicro_028542 Cc1ccc2c(Cl)c(sc2c1)C(=O)NCc3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D05 compound treatment 0.352 0.0092 0.76 0.352 0.00823 0.73 1.056 0.9997 1939941 CBMicro_028543 CCOc1ccccc1C(=O)Nc2cc(ccc2C)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D06 compound treatment 0.33 -0.0128 -1.06 0.336 -0.00777 -0.69 -1.2381 -0.9779 1398309 CBMicro_028544 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D07 compound treatment 0.318 -0.0248 -2.06 0.344 2.33E-4 0.02 -1.4412 -0.7 1195548 CBMicro_028545 CCOc1ccc(NC(=O)c2ccc3OCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D08 compound treatment 0.371 0.0282 2.34 0.38 0.0362 3.21 3.926 0.9879 1529920 CBMicro_028546 COc1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D09 compound treatment 0.334 -0.0088 -0.73 0.342 -0.00177 -0.16 -0.6273 -0.8396 1619101 CBMicro_028547 Cc1onc(c1C(=O)Nc2ccc(C)c(C)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D10 compound treatment 0.346 0.0032 0.27 0.359 0.0152 1.35 1.1424 0.8303 1939942 CBMicro_028548 Cc1onc(c1C(=O)Nc2ccc(cc2Br)[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D11 compound treatment 0.343 2.0E-4 0.02 0.355 0.0112 1.0 0.7157 0.7188 1315975 CBMicro_028549 O=C(CN1C(=O)c2ccccc2C1=O)n3c4CCCCc4c5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D12 compound treatment 0.37 0.0272 2.26 0.375 0.0312 2.77 3.554 0.9949 1939943 CBMicro_028550 Cc1ccc(c2csc(NC(=O)c3ccc(cc3Cl)[N+](=O)[O-])n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D13 compound treatment 0.333 -0.0098 -0.81 0.343 -7.67E-4 -0.07 -0.6233 -0.7635 1475478 CBMicro_028551 COc1ccc(CCC(=O)Nc2nccs2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D14 compound treatment 0.329 -0.0138 -1.15 0.339 -0.00477 -0.42 -1.1088 -0.9081 1522764 CBMicro_028552 CCC(Oc1ccccc1)C(=O)Nc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D15 compound treatment 0.328 -0.0148 -1.23 0.338 -0.00577 -0.51 -1.2302 -0.9244 1939944 CBMicro_028553 Cc1ccc(cc1NC(=O)CCCOc2ccc(Cl)cc2Cl)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D16 compound treatment 0.34 -0.0028 -0.23 0.343 -7.67E-4 -0.07 -0.2124 -0.8771 1646115 CBMicro_028554 COc1ccc(CC(=O)NCc2ccc(F)cc2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D17 compound treatment 0.338 -0.0048 -0.4 0.345 0.00123 0.11 -0.2045 -0.4949 1189808 CBMicro_028555 CC1CCc2c(C#N)c(NC(=O)c3cccc(F)c3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D18 compound treatment 0.358 0.0152 1.26 0.374 0.0302 2.68 2.7869 0.941 1431128 CBMicro_028556 Cc1ccc(o1)c2cc(C(=O)Nc3ccc(Br)cc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D19 compound treatment 0.399 0.0562 4.67 0.402 0.0582 5.16 6.9483 0.9987 1526188 CBMicro_028557 Cc1ccc(c2csc(NC(=O)c3sc4ccccc4c3Cl)n2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D20 compound treatment 0.338 -0.0048 -0.4 0.342 -0.00177 -0.16 -0.3925 -0.9167 1321678 CBMicro_028558 COc1ccc(Cl)cc1C(=O)Nc2sc(C)c(C)c2C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D21 compound treatment 0.332 -0.0108 -0.9 0.339 -0.00477 -0.42 -0.9327 -0.941 1590217 CBMicro_028559 COC(=O)c1cc(NC(=O)c2ccc3OCOc3c2)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D22 compound treatment 0.342 -8.0E-4 -0.07 0.346 0.00223 0.2 0.093 0.4454 1617099 CBMicro_028560 CN1CCN(CC1)C(=O)c2c(C)onc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D23 positive control 0.084 -0.259 -21.49 0.085 -0.259 -22.93 -31.4081 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 D24 positive control 0.09 -0.253 -20.99 0.092 -0.252 -22.31 -30.6172 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E01 mock treatment 0.334 -0.0088 -0.73 0.337 -0.00677 -0.6 -0.9406 -0.9952 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E02 mock treatment 0.343 2.0E-4 0.02 0.343 -7.67E-4 -0.07 -0.0363 -0.519 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E03 compound treatment 0.34 -0.0028 -0.23 0.351 0.00723 0.64 0.2889 0.4237 1512721 CBMicro_028561 CCOc1ccc(cc1)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E04 compound treatment 0.392 0.0492 4.08 0.389 0.0452 4.01 5.7228 1.0 1353191 CBMicro_028562 Cc1cccc(N2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E05 compound treatment 0.337 -0.0058 -0.48 0.338 -0.00577 -0.51 -0.7018 -0.9996 1043142 CBMicro_028563 CN(C)c1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E06 compound treatment 0.289 -0.0538 -4.47 0.297 -0.0468 -4.14 -6.0889 -0.9993 1939945 CBMicro_028564 Cc1cc(C)c(c(C)c1)S(=O)(=O)NNc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E07 compound treatment 0.365 0.0222 1.84 0.361 0.0172 1.53 2.3831 0.9956 1939946 CBMicro_028565 CC/C(=N\NC(=O)c1ccc(C)o1)/c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E08 compound treatment 0.336 -0.0068 -0.56 0.337 -0.00677 -0.6 -0.8232 -0.9995 1541402 CBMicro_028566 COc1ccc(OCC(=O)NCc2ccc3OCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E09 compound treatment 0.355 0.0122 1.01 0.349 0.00523 0.46 1.0441 0.9373 1713491 CBMicro_028567 CCOc1ccccc1N2CCN(CC2)C(=O)CCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E10 compound treatment 0.361 0.0182 1.51 0.35 0.00623 0.55 1.459 0.9069 1225086 CBMicro_028568 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(F)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E11 compound treatment 0.325 -0.0178 -1.48 0.342 -0.00177 -0.16 -1.1556 -0.7777 1525103 CBMicro_028569 COc1ccc(Cl)cc1C(=O)Nc2ccc(cc2)S(=O)(=O)NC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E12 compound treatment 0.346 0.0032 0.27 0.343 -7.67E-4 -0.07 0.1398 0.5099 1414900 CBMicro_028570 COc1ccc(CCNC(=O)C2CC2c3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E13 compound treatment 0.365 0.0222 1.84 0.383 0.0392 3.48 3.7618 0.9559 1738483 CBMicro_028571 COc1ccc(Cl)cc1C(=O)Nc2cc(C)cc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E14 compound treatment 0.335 -0.0078 -0.65 0.339 -0.00477 -0.42 -0.7566 -0.9786 1369083 CBMicro_028572 Cc1ccc(cc1)N2C(=O)c3cccc4c(ccc(C2=O)c34)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E15 compound treatment 0.379 0.0362 3.01 0.386 0.0422 3.74 4.7716 0.9941 1400581 CBMicro_028573 Clc1ccc(NC(=O)Nc2ccc3OCCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E16 compound treatment 0.335 -0.0078 -0.65 0.34 -0.00377 -0.33 -0.6939 -0.9525 1939947 CBMicro_028574 Cc1sc(NC(=O)C2CC=CCC2C(=O)O)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E17 compound treatment 0.41 0.0672 5.58 0.401 0.0572 5.07 7.5314 0.9989 1939948 CBMicro_028575 Cc1sc(NC(=O)/C=C/c2ccc(C)cc2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E18 compound treatment 0.326 -0.0168 -1.39 0.336 -0.00777 -0.69 -1.4729 -0.947 1360719 CBMicro_028576 Cc1occc1C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E19 compound treatment 0.33 -0.0128 -1.06 0.333 -0.0108 -0.95 -1.4261 -0.9986 1939949 CBMicro_028577 COc1ccc(CCNC(=O)c2cc(Cl)ccc2[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E20 compound treatment 0.335 -0.0078 -0.65 0.338 -0.00577 -0.51 -0.8193 -0.9931 1003531 CBMicro_028578 OC(=O)c1ccccc1NC(=O)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E21 compound treatment 0.341 -0.0018 -0.15 0.344 2.33E-4 0.02 -0.091 -0.6035 1609758 CBMicro_028579 CCOC(=O)c1ccccc1NC(=O)c2cnccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E22 compound treatment 0.331 -0.0118 -0.98 0.336 -0.00777 -0.69 -1.1794 -0.9851 1939950 CBMicro_028580 CCn1c(/N=C/c2ccc(OC)c3cccc(OC)c23)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E23 positive control 0.084 -0.259 -21.49 0.086 -0.258 -22.84 -31.3454 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 E24 positive control 0.092 -0.251 -20.82 0.091 -0.253 -22.4 -30.5624 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F01 mock treatment 0.341 -0.0018 -0.15 0.339 -0.00477 -0.42 -0.4044 -0.9024 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F02 mock treatment 0.342 -8.0E-4 -0.07 0.344 2.33E-4 0.02 -0.0323 -0.4649 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F03 compound treatment 0.324 -0.0188 -1.56 0.342 -0.00177 -0.16 -1.2143 -0.7742 1602757 CBMicro_028581 COc1ccc(OC)c(NC(=O)CC(c2ccccc2)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F04 compound treatment 0.338 -0.0048 -0.4 0.34 -0.00377 -0.33 -0.5178 -0.9961 1611578 CBMicro_028582 COc1ccc(C(=O)N2CCN(CC2)c3cccc(C)c3C)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F05 compound treatment 0.347 0.0042 0.35 0.346 0.00223 0.2 0.3865 0.964 1522317 CBMicro_028583 COc1ccc(C)cc1NC(=O)c2cc(OC)c(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F06 compound treatment 0.325 -0.0178 -1.48 0.328 -0.0158 -1.4 -2.0329 -0.9996 1213789 CBMicro_028584 COC(=O)c1sccc1NC(=O)c2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F07 compound treatment 0.347 0.0042 0.35 0.344 2.33E-4 0.02 0.2612 0.7477 1551427 CBMicro_028585 CCOc1ccccc1N2CCN(CC2)C(=O)c3cccc(F)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F08 compound treatment 0.347 0.0042 0.35 0.355 0.0112 1.0 0.9505 0.9011 1189096 CBMicro_028586 CCN(CC)C(=O)c1sc(NC(=O)c2cc(Cl)ccc2OC)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F09 compound treatment 0.408 0.0652 5.41 0.417 0.0732 6.49 8.4166 0.9959 1939951 CBMicro_028587 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F10 compound treatment 0.35 0.0072 0.6 0.357 0.0132 1.17 1.2519 0.9511 1696976 CBMicro_028588 Cc1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F11 compound treatment 0.326 -0.0168 -1.39 0.351 0.00723 0.64 -0.5329 -0.3472 1312525 CBMicro_028589 CCc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F12 compound treatment 0.335 -0.0078 -0.65 0.346 0.00223 0.2 -0.3179 -0.4695 1145659 CBMicro_028590 CCN(CC)C(=O)c1sc(NC(=O)C2c3ccccc3Oc4ccccc24)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F13 compound treatment 0.375 0.0322 2.67 0.386 0.0422 3.74 4.5368 0.9864 1118141 CBMicro_028591 COc1ccc(CCNC(=O)c2sc3cc(C)ccc3c2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F14 compound treatment 0.388 0.0452 3.75 0.394 0.0502 4.45 5.8013 0.9964 1939952 CBMicro_028592 Cc1csc(NC(=O)c2cc(nc3ccccc23)c4cccc(Br)c4)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F15 compound treatment 0.346 0.0032 0.27 0.343 -7.67E-4 -0.07 0.1398 0.5099 1203521 CBMicro_028593 CC(Oc1ccc(Cl)cc1C)C(=O)NCc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F16 compound treatment 0.36 0.0172 1.43 0.387 0.0432 3.83 3.7189 0.9095 1165603 CBMicro_028594 CCc1c(C)sc(NC(=O)c2ccccc2F)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F17 compound treatment 0.339 -0.0038 -0.32 0.341 -0.00277 -0.25 -0.3964 -0.9922 1223105 CBMicro_028595 Cc1ccccc1N2C(=O)c3cccc4c(ccc(C2=O)c34)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F18 compound treatment 0.343 2.0E-4 0.02 0.343 -7.67E-4 -0.07 -0.0363 -0.519 1568128 CBMicro_028596 CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2c(C)c(nc3ccccc23)c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F19 compound treatment 0.357 0.0142 1.18 0.386 0.0422 3.74 3.4801 0.8869 1939953 CBMicro_028597 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nc2ccccc2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F20 compound treatment 0.366 0.0232 1.93 0.364 0.0202 1.79 2.6298 0.9994 1622635 CBMicro_028598 CC(C)(C)C1CCc2c(C#N)c(NC(=O)c3ccncc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F21 compound treatment 0.339 -0.0038 -0.32 0.343 -7.67E-4 -0.07 -0.2711 -0.8401 1939954 CBMicro_028599 CC(C)OC(=O)c1sc(NC(=O)c2cccc(F)c2)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F22 compound treatment 0.33 -0.0128 -1.06 0.336 -0.00777 -0.69 -1.2381 -0.9779 1493713 CBMicro_028600 CCOC(=O)c1ccccc1NC(=O)CCC2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F23 positive control 0.086 -0.257 -21.32 0.087 -0.257 -22.76 -31.1653 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 F24 positive control 0.09 -0.253 -20.99 0.091 -0.253 -22.4 -30.6798 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G01 mock treatment 0.337 -0.0058 -0.48 0.341 -0.00277 -0.25 -0.5139 -0.951 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G02 mock treatment 0.337 -0.0058 -0.48 0.362 0.0182 1.62 0.8021 0.4757 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G03 compound treatment 0.342 -8.0E-4 -0.07 0.386 0.0422 3.74 2.5996 0.6944 1684835 CBMicro_028601 CCOC(=O)c1sc(NC(=O)CCC2CCCC2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G04 compound treatment 0.373 0.0302 2.51 0.425 0.0812 7.2 6.8633 0.9003 1556543 CBMicro_028602 COC(=O)c1cc(NC(=O)C(Sc2ccccc2)c3ccccc3)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G05 compound treatment 0.366 0.0232 1.93 0.409 0.0652 5.78 5.4498 0.8944 1681880 CBMicro_028603 CCC(C(=O)Nc1nc(c(C)s1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G06 compound treatment 0.346 0.0032 0.27 0.391 0.0472 4.19 3.1477 0.7505 1291869 CBMicro_028604 COc1ccc(cc1OC)c2cc(C(=O)NC3(CC4CC5CC(C4)C3)C5)c6ccccc6n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G07 compound treatment 0.326 -0.0168 -1.39 0.366 0.0222 1.97 0.407 0.1686 1451608 CBMicro_028605 Cc1cccc(N2CCN(CC2)C(=O)c3cccc(Br)c3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G08 compound treatment 0.333 -0.0098 -0.81 0.351 0.00723 0.64 -0.122 -0.1178 1333292 CBMicro_028606 CCOC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3NC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G09 compound treatment 0.325 -0.0178 -1.48 0.34 -0.00377 -0.33 -1.281 -0.8455 1939955 CBMicro_028607 Clc1ccc(cc1)C(=O)NCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G10 compound treatment 0.331 -0.0118 -0.98 0.339 -0.00477 -0.42 -0.9914 -0.9293 1484575 CBMicro_028608 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cc(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G11 compound treatment 0.339 -0.0038 -0.32 0.339 -0.00477 -0.42 -0.5218 -0.9897 1491155 CBMicro_028609 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3Cl)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G12 compound treatment 0.323 -0.0198 -1.64 0.335 -0.00877 -0.78 -1.7117 -0.9415 1939956 CBMicro_028610 CN(C)CCCNC(=O)c1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G13 compound treatment 0.345 0.0022 0.18 0.343 -7.67E-4 -0.07 0.0811 0.4162 1414213 CBMicro_028611 CCc1c(C)sc(NC(=O)C2CCCCC2C(=O)O)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G14 compound treatment 0.314 -0.0288 -2.39 0.324 -0.0198 -1.75 -2.9293 -0.9883 1939957 CBMicro_028612 CC(C)(C)c1ccc(cc1)S(=O)(=O)NNc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G15 compound treatment 0.356 0.0132 1.1 0.362 0.0182 1.62 1.9175 0.9821 1302600 CBMicro_028613 CCC1CCc2c(C(=O)N)c(NC(=O)c3cnccn3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G16 compound treatment 0.351 0.0082 0.68 0.359 0.0152 1.35 1.436 0.9498 1939958 CBMicro_028614 COc1ccc(cc1OC)C(=O)Nc2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G17 compound treatment 0.358 0.0152 1.26 0.354 0.0102 0.91 1.5336 0.9869 1698960 CBMicro_028615 CCOc1ccccc1N2CCN(CC2)C(=O)C(Sc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G18 compound treatment 0.318 -0.0248 -2.06 0.332 -0.0118 -1.04 -2.1932 -0.9503 1939959 CBMicro_028616 Fc1ccc(/C=C/C(=O)N2CCN(CC2)c3cccc(Cl)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G19 compound treatment 0.341 -0.0018 -0.15 0.343 -7.67E-4 -0.07 -0.1537 -0.9364 1566909 CBMicro_028617 COc1ccc(CCNC(=O)c2ccc3OCOc3c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G20 compound treatment 0.357 0.0142 1.18 0.355 0.0112 1.0 1.5375 0.9965 1939960 CBMicro_028618 COc1cccc(/C=N/Nc2nc(cc(n2)c3ccc(OC)c(OC)c3)c4ccc(C)cc4)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G21 compound treatment 0.35 0.0072 0.6 0.348 0.00423 0.38 0.6879 0.9748 1339080 CBMicro_028619 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(cc2)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G22 compound treatment 0.326 -0.0168 -1.39 0.334 -0.00977 -0.87 -1.5982 -0.9737 1289497 CBMicro_028620 CCCCn1c(=O)c(C(=O)Nc2cccc(O)c2)c(O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G23 positive control 0.086 -0.257 -21.32 0.087 -0.257 -22.76 -31.1653 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 G24 positive control 0.093 -0.25 -20.74 0.094 -0.25 -22.13 -30.3157 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H01 mock treatment 0.338 -0.0048 -0.4 0.346 0.00223 0.2 -0.1418 -0.3188 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H02 mock treatment 0.344 0.0012 0.1 0.344 2.33E-4 0.02 0.0851 0.8361 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H03 compound treatment 0.322 -0.0208 -1.73 0.331 -0.0128 -1.13 -2.0211 -0.979 1939961 CBMicro_028621 Fc1ccc(/C=C/C(=O)NC2CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H04 compound treatment 0.348 0.0052 0.43 0.363 0.0192 1.7 1.5105 0.8591 1256534 CBMicro_028622 Cc1cccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H05 compound treatment 0.318 -0.0248 -2.06 0.332 -0.0118 -1.04 -2.1932 -0.9503 1939962 CBMicro_028623 CC(=O)Nc1ccc(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H06 compound treatment 0.325 -0.0178 -1.48 0.337 -0.00677 -0.6 -1.469 -0.9211 1939963 CBMicro_028624 C/C(=N\NC(=O)C(O)c1ccccc1)/c2cccc(NC(=O)c3ccco3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H07 compound treatment 0.344 0.0012 0.1 0.354 0.0102 0.91 0.7117 0.7801 1939964 CBMicro_028625 COc1ccc(/C=C/C(=O)Nc2cc(ccc2C)S(=O)(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H08 compound treatment 0.322 -0.0208 -1.73 0.341 -0.00277 -0.25 -1.3944 -0.7995 1615340 CBMicro_028626 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ncccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H09 compound treatment 0.349 0.0062 0.51 0.357 0.0132 1.17 1.1932 0.9317 1462102 CBMicro_028627 Cc1ccc(o1)c2cc(C(=O)N3CCCCCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H10 compound treatment 0.325 -0.0178 -1.48 0.331 -0.0128 -1.13 -1.8449 -0.9913 1939965 CBMicro_028628 O=C(NCCCn1ccnc1)NC2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H11 compound treatment 0.333 -0.0098 -0.81 0.336 -0.00777 -0.69 -1.062 -0.9965 1939966 CBMicro_028629 O=C(/C=C/c1ccc2OCOc2c1)N3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H12 compound treatment 0.326 -0.0168 -1.39 0.328 -0.0158 -1.4 -1.9742 -1.0 1939967 CBMicro_028630 NC(=O)c1c(NC(=O)C2C(C3CC2C=C3)C(=O)O)sc4CCCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H13 compound treatment 0.337 -0.0058 -0.48 0.341 -0.00277 -0.25 -0.5139 -0.951 1939968 CBMicro_028631 COc1cc(OC)cc(c1)C(=O)NCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H14 compound treatment 0.342 -8.0E-4 -0.07 0.348 0.00423 0.38 0.2183 0.573 1406591 CBMicro_028632 Cn1c(NC(=O)c2cc(nc3ccccc23)c4ccc(Br)cc4)cc(=O)n(C)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H15 compound treatment 0.352 0.0092 0.76 0.384 0.0402 3.57 3.0613 0.8395 1147723 CBMicro_028633 CN(C)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H16 compound treatment 0.332 -0.0108 -0.9 0.339 -0.00477 -0.42 -0.9327 -0.941 1939969 CBMicro_028634 Fc1ccc(/C=C/C(=O)NCc2ccccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H17 compound treatment 0.344 0.0012 0.1 0.346 0.00223 0.2 0.2104 0.9495 1139600 CBMicro_028635 Clc1cccc(c1)N2CCN(CC2)C(=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H18 compound treatment 0.364 0.0212 1.76 0.373 0.0292 2.59 3.0764 0.9823 1609148 CBMicro_028636 CCN(CC)c1ccc(NC(=O)Cc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H19 compound treatment 0.331 -0.0118 -0.98 0.333 -0.0108 -0.95 -1.3674 -0.9999 1560739 CBMicro_028637 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H20 compound treatment 0.432 0.0892 7.41 0.446 0.102 9.06 11.6428 0.995 1638556 CBMicro_028638 CN(C)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H21 compound treatment 0.374 0.0312 2.59 0.381 0.0372 3.3 4.1648 0.9928 1656934 CBMicro_028639 Cc1sc(NC(=O)CC(c2ccccc2)c3ccccc3)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H22 compound treatment 0.375 0.0322 2.67 0.375 0.0312 2.77 3.8475 0.9998 1939970 CBMicro_028640 COc1ccc(/C=C/C(=O)\C=C\c2ccc(cc2)N(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H23 positive control 0.087 -0.256 -21.24 0.087 -0.257 -22.76 -31.1066 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 H24 positive control 0.096 -0.247 -20.49 0.094 -0.25 -22.13 -30.1396 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I01 mock treatment 0.346 0.0032 0.27 0.351 0.00723 0.64 0.6411 0.9239 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I02 mock treatment 0.346 0.0032 0.27 0.354 0.0102 0.91 0.8291 0.8774 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I03 compound treatment 0.343 2.0E-4 0.02 0.352 0.00823 0.73 0.5277 0.723 1495745 CBMicro_028641 CC(C)CNC(=O)c1cc(nc2ccccc12)c3ccc(C)cc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I04 compound treatment 0.327 -0.0158 -1.31 0.331 -0.0128 -1.13 -1.7275 -0.9973 1591200 CBMicro_028642 Clc1ccc(NC(=O)C2CCCO2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I05 compound treatment 0.336 -0.0068 -0.56 0.338 -0.00577 -0.51 -0.7606 -0.9988 1385161 CBMicro_028643 Cc1ccc(cc1C)c2cc(C(=O)Nc3ccncc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I06 compound treatment 0.376 0.0332 2.76 0.378 0.0342 3.03 4.0942 0.9989 1381687 CBMicro_028644 CC1CCc2c(C#N)c(NC(=O)c3ccoc3C)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I07 compound treatment 0.364 0.0212 1.76 0.38 0.0362 3.21 3.5151 0.9599 1445974 CBMicro_028645 Clc1c(sc2ccccc12)C(=O)Nc3nccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I08 compound treatment 0.353 0.0102 0.85 0.361 0.0172 1.53 1.6787 0.9613 1557594 CBMicro_028646 COc1ccc(CCNC(=O)c2cnccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I09 compound treatment 0.351 0.0082 0.68 0.357 0.0132 1.17 1.3106 0.9665 1939971 CBMicro_028647 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)c3sc4cc(C)ccc4c3Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I10 compound treatment 0.339 -0.0038 -0.32 0.343 -7.67E-4 -0.07 -0.2711 -0.8401 1939972 CBMicro_028648 Cc1ccc(c(C)c1)S(=O)(=O)n2nnc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I11 compound treatment 0.346 0.0032 0.27 0.351 0.00723 0.64 0.6411 0.9239 1939973 CBMicro_028649 Cc1onc(c1C(=O)Nc2ccc3ccccc3c2)c4c(Cl)cccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I12 compound treatment 0.348 0.0052 0.43 0.347 0.00323 0.29 0.5079 0.9802 1405421 CBMicro_028650 COc1ccc(c(OC)c1)c2cc(C(=O)NCCc3ccc(OC)c(OC)c3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I13 compound treatment 0.345 0.0022 0.18 0.353 0.00923 0.82 0.7078 0.8442 1399586 CBMicro_028651 COc1cc(OC)cc(c1)C(=O)Nc2ccc(cc2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I14 compound treatment 0.316 -0.0268 -2.22 0.34 -0.00377 -0.33 -1.8093 -0.8042 1939974 CBMicro_028652 CCc1ccc(/C=N/NC(=O)c2c[nH]c3ccccc23)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I15 compound treatment 0.351 0.0082 0.68 0.325 -0.0188 -1.66 -0.6946 -0.3865 1939975 CBMicro_028653 Cc1cc(Cl)ccc1OCC(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I16 compound treatment 0.342 -8.0E-4 -0.07 0.343 -7.67E-4 -0.07 -0.095 -0.9999 1518296 CBMicro_028654 Cc1ccc(cc1)c2csc(NC(=O)CCCC(=O)O)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I17 compound treatment 0.351 0.0082 0.68 0.357 0.0132 1.17 1.3106 0.9665 1540504 CBMicro_028655 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(C)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I18 compound treatment 0.342 -8.0E-4 -0.07 0.348 0.00423 0.38 0.2183 0.573 1939976 CBMicro_028656 Clc1ccccc1/C=C/C(=O)NCc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I19 compound treatment 0.356 0.0132 1.1 0.359 0.0152 1.35 1.7295 0.9946 1939977 CBMicro_028657 COC(=O)c1sccc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I20 compound treatment 0.388 0.0452 3.75 0.401 0.0572 5.07 6.2399 0.989 1939978 CBMicro_028658 Oc1ccc(cc1/C=C/2\C(=O)NN(C2=O)c3ccc(Cl)c(Cl)c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I21 compound treatment 0.345 0.0022 0.18 0.344 2.33E-4 0.02 0.1438 0.7822 1939979 CBMicro_028659 Cc1sc(NC(=O)/C=C/c2cccc(Cl)c2)nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I22 compound treatment 0.336 -0.0068 -0.56 0.341 -0.00277 -0.25 -0.5726 -0.9303 1939980 CBMicro_028660 COC(=O)C1=C(C)NC(=O)CC1c2ccccc2C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I23 positive control 0.089 -0.254 -21.07 0.087 -0.257 -22.76 -30.9892 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 I24 positive control 0.094 -0.249 -20.66 0.094 -0.25 -22.13 -30.257 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J01 mock treatment 0.318 -0.0248 -2.06 0.327 -0.0168 -1.49 -2.5065 -0.9872 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J02 mock treatment 0.35 0.0072 0.6 0.351 0.00723 0.64 0.8759 0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J03 compound treatment 0.321 -0.0218 -1.81 0.329 -0.0148 -1.31 -2.2051 -0.9873 1450024 CBMicro_028661 Cc1onc(c1C(=O)Nc2nnn[nH]2)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J04 compound treatment 0.335 -0.0078 -0.65 0.339 -0.00477 -0.42 -0.7566 -0.9786 1154823 CBMicro_028662 COc1ccc(CCNC(=O)C2CCCC2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J05 compound treatment 0.363 0.0202 1.68 0.373 0.0292 2.59 3.0177 0.9778 1665583 CBMicro_028663 CCOC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J06 compound treatment 0.33 -0.0128 -1.06 0.342 -0.00177 -0.16 -0.8621 -0.8026 1939981 CBMicro_028664 CCSc1nnc(NC(=O)/C=C/c2ccc(Cl)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J07 compound treatment 0.347 0.0042 0.35 0.347 0.00323 0.29 0.4492 0.9953 1737003 CBMicro_028665 CCOc1ccccc1N2CCN(CC2)C(=O)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J08 compound treatment 0.34 -0.0028 -0.23 0.356 0.0122 1.08 0.6022 0.5431 1939982 CBMicro_028666 CN1CCN(CC1)NC(=O)c2ccc(Cl)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J09 compound treatment 0.372 0.0292 2.42 0.39 0.0462 4.1 4.6114 0.9686 1717200 CBMicro_028667 CCc1c(C)sc(NC(=O)CCc2ccc(OC)cc2)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J10 compound treatment 0.331 -0.0118 -0.98 0.34 -0.00377 -0.33 -0.9287 -0.8974 1939983 CBMicro_028668 CCN1CCC(=NNS(=O)(=O)c2ccc(Cl)cc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J11 compound treatment 0.349 0.0062 0.51 0.353 0.00923 0.82 0.9426 0.975 1242477 CBMicro_028669 CCSc1nnc(NC(=O)c2c(OC)cccc2OC)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J12 compound treatment 0.34 -0.0028 -0.23 0.342 -0.00177 -0.16 -0.2751 -0.9815 1120384 CBMicro_028670 Cc1ccc2nc(NC(=O)C3CCCO3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J13 compound treatment 0.349 0.0062 0.51 0.35 0.00623 0.55 0.7546 0.9994 1394771 CBMicro_028671 CCC(Oc1ccccc1)C(=O)N2CCN(CC2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J14 compound treatment 0.371 0.0282 2.34 0.376 0.0322 2.86 3.6753 0.9951 1939984 CBMicro_028672 COc1ccc(/C=C/C(=O)Nc2ccc(C)cc2C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J15 compound treatment 0.346 0.0032 0.27 0.359 0.0152 1.35 1.1424 0.8303 1377301 CBMicro_028673 O=C1CCCC(=O)C1c2cc(NS(=O)(=O)c3ccccc3)ccc2NS(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J16 compound treatment 0.369 0.0262 2.18 0.376 0.0322 2.86 3.5579 0.991 1939985 CBMicro_028674 COC(=O)c1sccc1NC(=O)/C=C/c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J17 compound treatment 0.347 0.0042 0.35 0.377 0.0332 2.95 2.3291 0.7853 1293383 CBMicro_028675 COc1ccc(Cl)cc1C(=O)Nc2ccc(cc2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J18 compound treatment 0.375 0.0322 2.67 0.378 0.0342 3.03 4.0355 0.998 1216929 CBMicro_028676 CC1CCc2c(C#N)c(NC(=O)c3ccc(C)c(C)c3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J19 compound treatment 0.342 -8.0E-4 -0.07 0.358 0.0142 1.26 0.845 0.6689 1939986 CBMicro_028677 Cc1ccc(c(C)c1)S(=O)(=O)Nc2ccc(NS(=O)(=O)c3ccc(C)cc3C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J20 compound treatment 0.324 -0.0188 -1.56 0.342 -0.00177 -0.16 -1.2143 -0.7742 1231270 CBMicro_028678 Cc1c(NS(=O)(=O)c2ccccc2C)c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J21 compound treatment 0.34 -0.0028 -0.23 0.344 2.33E-4 0.02 -0.1497 -0.6417 1436106 CBMicro_028679 O=C(N1CCOCC1)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J22 compound treatment 0.355 0.0122 1.01 0.355 0.0112 1.0 1.4201 1.0 1939987 CBMicro_028680 COc1ccc2N(C(=O)/C=C/C)C(C)(C)C=C(C)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J23 positive control 0.088 -0.255 -21.15 0.091 -0.253 -22.4 -30.7972 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 J24 positive control 0.094 -0.249 -20.66 0.094 -0.25 -22.13 -30.257 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K01 mock treatment 0.344 0.0012 0.1 0.346 0.00223 0.2 0.2104 0.9495 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K02 mock treatment 0.344 0.0012 0.1 0.348 0.00423 0.38 0.3357 0.8649 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K03 compound treatment 0.332 -0.0108 -0.9 0.332 -0.0118 -1.04 -1.3714 -0.9972 1939988 CBMicro_028681 COC(=O)c1sc(NC(=O)/C=C/c2cccc(c2)[N+](=O)[O-])c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K04 compound treatment 0.349 0.0062 0.51 0.361 0.0172 1.53 1.4439 0.8959 1662042 CBMicro_028682 CC1CC(N(C(=O)c2ccc(Cl)cc2)c3ccccc3)c4ccccc4N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K05 compound treatment 0.333 -0.0098 -0.81 0.34 -0.00377 -0.33 -0.8113 -0.9226 1357061 CBMicro_028683 Cc1cc(C)nc(NC(=O)C2C(C3CC2C=C3)C(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K06 compound treatment 0.343 2.0E-4 0.02 0.349 0.00523 0.46 0.3397 0.732 1381614 CBMicro_028684 CCOC(=O)Nc1sc2CC(C)CCc2c1C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K07 compound treatment 0.338 -0.0048 -0.4 0.342 -0.00177 -0.16 -0.3925 -0.9167 1124645 CBMicro_028685 Cc1cccc(N2CCN(CC2)C(=O)c3cccnc3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K08 compound treatment 0.344 0.0012 0.1 0.341 -0.00277 -0.25 -0.1029 -0.3889 1672797 CBMicro_028686 CCN(CC)C(=O)c1sc(NC(=O)c2ccc(OC)cc2)c(C(=O)OC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K09 compound treatment 0.33 -0.0128 -1.06 0.332 -0.0118 -1.04 -1.4888 -1.0 1457254 CBMicro_028687 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ncccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K10 compound treatment 0.34 -0.0028 -0.23 0.346 0.00223 0.2 -0.0244 -0.08 1644771 CBMicro_028688 CC(Oc1ccc(Cl)cc1Cl)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K11 compound treatment 0.403 0.0602 5.0 0.403 0.0592 5.25 7.2458 0.9997 1939989 CBMicro_028689 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)/C=C/c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K12 compound treatment 0.363 0.0202 1.68 0.377 0.0332 2.95 3.2684 0.9644 1440663 CBMicro_028690 CC1CCc2c(C#N)c(NC(=O)c3cccnc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K13 compound treatment 0.416 0.0732 6.08 0.417 0.0732 6.49 8.8863 0.9995 1648687 CBMicro_028691 CCOc1ccc(cc1)c2cc(C(=O)Nc3c(C)cccc3CC)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K14 compound treatment 0.339 -0.0038 -0.32 0.342 -0.00177 -0.16 -0.3338 -0.9477 1939990 CBMicro_028692 COc1ccc(C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K15 compound treatment 0.334 -0.0088 -0.73 0.344 2.33E-4 0.02 -0.502 -0.6868 1324194 CBMicro_028693 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K16 compound treatment 0.387 0.0442 3.67 0.395 0.0512 4.54 5.8052 0.9944 1939991 CBMicro_028694 Fc1ccc(cc1)C2C3(OC(c4ccc(Br)cc4)C25C(=O)c6ccccc6C5=O)C(=O)c7ccccc7C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K17 compound treatment 0.327 -0.0158 -1.31 0.336 -0.00777 -0.69 -1.4142 -0.9547 1939992 CBMicro_028695 CC(=O)Nc1ccc(cc1)S(=O)(=O)/N=C/2\C=CC(=O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K18 compound treatment 0.422 0.0792 6.58 0.428 0.0842 7.46 9.9278 0.998 1223770 CBMicro_028696 Cc1ccc(s1)c2cc(C(=O)Nc3cc(C)cc(C)n3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K19 compound treatment 0.336 -0.0068 -0.56 0.338 -0.00577 -0.51 -0.7606 -0.9988 1939993 CBMicro_028697 CC(C)N1CCC(=NNC(=O)C2CC2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K20 compound treatment 0.364 0.0212 1.76 0.359 0.0152 1.35 2.1991 0.9914 1939994 CBMicro_028698 CCOc1cc(cc(/C=C/2\SC(=S)N(C)C2=O)c1O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K21 compound treatment 0.349 0.0062 0.51 0.352 0.00823 0.73 0.8799 0.9854 1332403 CBMicro_028699 CCSc1nnc(NC(=O)C2CC2c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K22 compound treatment 0.326 -0.0168 -1.39 0.334 -0.00977 -0.87 -1.5982 -0.9737 1782893 CBMicro_028700 COc1ccc(CNCc2ccc(cc2)[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K23 positive control 0.088 -0.255 -21.15 0.088 -0.256 -22.67 -30.9852 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 K24 positive control 0.098 -0.245 -20.32 0.095 -0.249 -22.05 -29.9596 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L01 mock treatment 0.342 -8.0E-4 -0.07 0.348 0.00423 0.38 0.2183 0.573 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L02 mock treatment 0.345 0.0022 0.18 0.342 -0.00177 -0.16 0.0184 0.0766 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L03 compound treatment 0.333 -0.0098 -0.81 0.341 -0.00277 -0.25 -0.7487 -0.8811 1623986 CBMicro_028701 O=C(NCc1ccco1)c2cc(nc3ccccc23)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L04 compound treatment 0.331 -0.0118 -0.98 0.335 -0.00877 -0.78 -1.2421 -0.9934 1561564 CBMicro_028702 COc1ccc(Cl)cc1C(=O)NCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L05 compound treatment 0.333 -0.0098 -0.81 0.347 0.00323 0.29 -0.3727 -0.4321 1637075 CBMicro_028703 O=C(C1c2ccccc2Oc3ccccc13)N4CCN(CC4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L06 compound treatment 0.338 -0.0048 -0.4 0.344 2.33E-4 0.02 -0.2672 -0.6695 1569956 CBMicro_028704 Cc1nnc(NC(=O)c2cc(nc3ccccc23)c4cccs4)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L07 compound treatment 0.327 -0.0158 -1.31 0.336 -0.00777 -0.69 -1.4142 -0.9547 1589554 CBMicro_028705 CN1CCN(CC1)NC(=O)COc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L08 compound treatment 0.359 0.0162 1.34 0.373 0.0292 2.59 2.7829 0.9534 1520379 CBMicro_028706 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L09 compound treatment 0.365 0.0222 1.84 0.386 0.0422 3.74 3.9498 0.9467 1526548 CBMicro_028707 O=C(Nc1sc2CCCCCCc2c1C#N)C3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L10 compound treatment 0.353 0.0102 0.85 0.346 0.00223 0.2 0.7387 0.8495 1149171 CBMicro_028708 CCCC1CCc2c(C(=O)N)c(NC(=O)c3ccccc3F)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L11 compound treatment 0.344 0.0012 0.1 0.338 -0.00577 -0.51 -0.2909 -0.5587 1245547 CBMicro_028709 O=C(CC#N)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L12 compound treatment 0.34 -0.0028 -0.23 0.34 -0.00377 -0.33 -0.4004 -0.9844 1526955 CBMicro_028710 Cc1ccccc1c2cc(C(=O)N3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L13 compound treatment 0.34 -0.0028 -0.23 0.35 0.00623 0.55 0.2262 0.3775 1939995 CBMicro_028711 COC(=O)c1cc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L14 compound treatment 0.361 0.0182 1.51 0.352 0.00823 0.73 1.5843 0.9442 1306187 CBMicro_028712 Cc1ccc(s1)c2cc(C(=O)N(CC=C)CC=C)c3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L15 compound treatment 0.326 -0.0168 -1.39 0.339 -0.00477 -0.42 -1.2849 -0.8817 1939996 CBMicro_028713 Brc1ccc(o1)C(=O)NCCCn2ccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L16 compound treatment 0.354 0.0112 0.93 0.353 0.00923 0.82 1.2361 0.998 1135230 CBMicro_028714 Clc1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L17 compound treatment 0.349 0.0062 0.51 0.352 0.00823 0.73 0.8799 0.9854 1675628 CBMicro_028715 CC1CCc2c(C(=O)N)c(NC(=O)c3ccc(Cl)c(Cl)c3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L18 compound treatment 0.344 0.0012 0.1 0.343 -7.67E-4 -0.07 0.0224 0.1858 1636439 CBMicro_028716 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L19 compound treatment 0.353 0.0102 0.85 0.361 0.0172 1.53 1.6787 0.9613 1295624 CBMicro_028717 CCOc1ccc(cc1)C(=O)Nc2ccsc2C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L20 compound treatment 0.353 0.0102 0.85 0.352 0.00823 0.73 1.1147 0.9973 1633723 CBMicro_028718 COc1ccc(CC(=O)Nc2nc(cs2)c3ccc4ccccc4c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L21 compound treatment 0.338 -0.0048 -0.4 0.34 -0.00377 -0.33 -0.5178 -0.9961 1939997 CBMicro_028719 COc1ccc(OC)c(NC(=O)C2C(C3CC2C=C3)C(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L22 compound treatment 0.329 -0.0138 -1.15 0.337 -0.00677 -0.6 -1.2341 -0.9544 1939998 CBMicro_028720 CCCN(CCC)CCCNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L23 positive control 0.089 -0.254 -21.07 0.088 -0.256 -22.67 -30.9265 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 L24 positive control 0.095 -0.248 -20.57 0.097 -0.247 -21.87 -30.0103 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M01 mock treatment 0.343 2.0E-4 0.02 0.342 -0.00177 -0.16 -0.099 -0.6286 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M02 mock treatment 0.341 -0.0018 -0.15 0.341 -0.00277 -0.25 -0.279 -0.9718 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M03 compound treatment 0.321 -0.0218 -1.81 0.331 -0.0128 -1.13 -2.0798 -0.9744 1690182 CBMicro_028721 Clc1ccc(NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M04 compound treatment 0.337 -0.0058 -0.48 0.339 -0.00477 -0.42 -0.6392 -0.9979 1186837 CBMicro_028722 CCNC(=O)c1cc(nc2ccccc12)c3ccc(Cl)s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M05 compound treatment 0.335 -0.0078 -0.65 0.346 0.00223 0.2 -0.3179 -0.4695 1939999 CBMicro_028723 COC(=O)c1sccc1NC(=O)/C=C/c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M06 compound treatment 0.342 -8.0E-4 -0.07 0.348 0.00423 0.38 0.2183 0.573 1940000 CBMicro_028724 Fc1ccc(cc1)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M07 compound treatment 0.342 -8.0E-4 -0.07 0.352 0.00823 0.73 0.469 0.6401 1368397 CBMicro_028725 CCOC(=O)c1sc(NC(=O)C2c3ccccc3Oc4ccccc24)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M08 compound treatment 0.406 0.0632 5.25 0.417 0.0732 6.49 8.2992 0.9944 1940001 CBMicro_028726 [O-][N+](=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccco4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M09 compound treatment 0.328 -0.0148 -1.23 0.336 -0.00777 -0.69 -1.3555 -0.9625 1510842 CBMicro_028727 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M10 compound treatment 0.326 -0.0168 -1.39 0.329 -0.0148 -1.31 -1.9116 -0.9995 1704821 CBMicro_028728 COC(=O)c1cc(NC(=O)CCCC(=O)O)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M11 compound treatment 0.347 0.0042 0.35 0.353 0.00923 0.82 0.8252 0.9277 1371013 CBMicro_028729 Cc1ccc2nc(NC(=O)C3CC3c4ccccc4)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M12 compound treatment 0.358 0.0152 1.26 0.371 0.0272 2.41 2.5989 0.9543 1507566 CBMicro_028730 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(Cl)ccc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M13 compound treatment 0.33 -0.0128 -1.06 0.342 -0.00177 -0.16 -0.8621 -0.8026 1282224 CBMicro_028731 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M14 compound treatment 0.333 -0.0098 -0.81 0.339 -0.00477 -0.42 -0.874 -0.9534 1281423 CBMicro_028732 O=C(C(Sc1ccccc1)c2ccccc2)N3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M15 compound treatment 0.346 0.0032 0.27 0.35 0.00623 0.55 0.5785 0.9437 1940002 CBMicro_028733 COC(=O)c1sccc1NC(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M16 compound treatment 0.346 0.0032 0.27 0.36 0.0162 1.44 1.2051 0.8238 1872633 CBMicro_028734 [O-][N+](=O)c1ccc(cc1)C(=O)n2c3CCCCc3c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M17 compound treatment 0.355 0.0122 1.01 0.356 0.0122 1.08 1.4828 0.9994 1940003 CBMicro_028735 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2ccc(cc2)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M18 compound treatment 0.329 -0.0138 -1.15 0.338 -0.00577 -0.51 -1.1715 -0.9338 1592641 CBMicro_028736 COc1ccc(C)cc1NC(=O)CCC2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M19 compound treatment 0.351 0.0082 0.68 0.349 0.00523 0.46 0.8093 0.9825 1144137 CBMicro_028737 CCOC(=O)c1ccc(NC(=O)c2ccc3OCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M20 compound treatment 0.369 0.0262 2.18 0.366 0.0222 1.97 2.9313 0.9988 1382290 CBMicro_028738 Fc1ccc(CC(=O)Nc2cccc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M21 compound treatment 0.337 -0.0058 -0.48 0.338 -0.00577 -0.51 -0.7018 -0.9996 1940004 CBMicro_028739 CC(=O)NS(=O)(=O)c1ccc(NC(=O)/C=C/c2ccc(F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M22 compound treatment 0.345 0.0022 0.18 0.343 -7.67E-4 -0.07 0.0811 0.4162 1538124 CBMicro_028740 Cc1ncsc1CCOC(=O)C2(CC3CC4CC(C)(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M23 positive control 0.089 -0.254 -21.07 0.092 -0.252 -22.31 -30.6759 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 M24 positive control 0.095 -0.248 -20.57 0.097 -0.247 -21.87 -30.0103 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N01 mock treatment 0.347 0.0042 0.35 0.346 0.00223 0.2 0.3865 0.964 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N02 mock treatment 0.349 0.0062 0.51 0.348 0.00423 0.38 0.6292 0.9879 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N03 compound treatment 0.337 -0.0058 -0.48 0.343 -7.67E-4 -0.07 -0.3885 -0.799 1224510 CBMicro_028741 CCOC(=O)c1sc(NC(=O)C2CCCCC2)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N04 compound treatment 0.333 -0.0098 -0.81 0.336 -0.00777 -0.69 -1.062 -0.9965 1174045 CBMicro_028742 Cc1ccc2c(Cl)c(sc2c1)C(=O)NCc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N05 compound treatment 0.351 0.0082 0.68 0.352 0.00823 0.73 0.9973 0.9994 1630716 CBMicro_028743 Clc1c(sc2ccccc12)C(=O)N3CCN(Cc4ccccc4)CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N06 compound treatment 0.346 0.0032 0.27 0.345 0.00123 0.11 0.2651 0.923 1169967 CBMicro_028744 CC(Oc1cccc(Cl)c1)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N07 compound treatment 0.343 2.0E-4 0.02 0.344 2.33E-4 0.02 0.0264 0.9941 1545906 CBMicro_028745 COc1ccccc1N2CCN(CC2)C(=O)c3sc4cc(C)ccc4c3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N08 compound treatment 0.352 0.0092 0.76 0.36 0.0162 1.44 1.5573 0.9561 1610113 CBMicro_028746 COc1ccc(cc1)c2cc(C(=O)NCc3ccc(C)cc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N09 compound treatment 0.358 0.0152 1.26 0.369 0.0252 2.24 2.4735 0.9633 1940005 CBMicro_028747 COc1cc(cc(OC)c1OC)C(=O)N/N=C(\C)/c2ccc(NC(=O)c3cccs3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N10 compound treatment 0.352 0.0092 0.76 0.348 0.00423 0.38 0.8054 0.9464 1421388 CBMicro_028748 CCOc1cc(cc(OCC)c1OCC)C(=O)N2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N11 compound treatment 0.348 0.0052 0.43 0.351 0.00723 0.64 0.7585 0.9815 1557380 CBMicro_028749 CCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N12 compound treatment 0.346 0.0032 0.27 0.346 0.00223 0.2 0.3278 0.9895 1940006 CBMicro_028750 Cc1c(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)c(=O)n(c5ccccc5)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N13 compound treatment 0.344 0.0012 0.1 0.35 0.00623 0.55 0.4611 0.8214 1940007 CBMicro_028751 Cc1cc(ccc1[N+](=O)[O-])C(=O)NCCCn2ccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N14 compound treatment 0.352 0.0092 0.76 0.36 0.0162 1.44 1.5573 0.9561 1686325 CBMicro_028752 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)OC)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N15 compound treatment 0.34 -0.0028 -0.23 0.342 -0.00177 -0.16 -0.2751 -0.9815 1318883 CBMicro_028753 O=C(CCC1CCCCC1)NCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N16 compound treatment 0.359 0.0162 1.34 0.359 0.0152 1.35 1.9056 1.0 1556552 CBMicro_028754 NC(=O)c1c(NC(=O)c2ccc(Br)cc2)sc3CCCCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N17 compound treatment 0.353 0.0102 0.85 0.357 0.0132 1.17 1.428 0.9872 1275921 CBMicro_028755 CCc1c(C)sc(NC(=O)C(C)Oc2cccc(Cl)c2)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N18 compound treatment 0.351 0.0082 0.68 0.368 0.0242 2.15 2.0 0.8877 1532014 CBMicro_028756 Cc1c(nc2ccccc2c1C(=O)NCc3ccc4OCOc4c3)c5ccc(Cl)cc5Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N19 compound treatment 0.354 0.0112 0.93 0.353 0.00923 0.82 1.2361 0.998 1176640 CBMicro_028757 CCN(CC)C(=O)c1sc(NC(=O)c2cc(Cl)ccc2Cl)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N20 compound treatment 0.35 0.0072 0.6 0.349 0.00523 0.46 0.7506 0.9921 1141384 CBMicro_028758 COc1ccccc1NC(=O)c2ccc(cc2)N(Cc3ccccc3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N21 compound treatment 0.453 0.11 9.15 0.448 0.104 9.24 13.0009 1.0 1540982 CBMicro_028759 COc1ccc(cc1OC)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N22 compound treatment 0.339 -0.0038 -0.32 0.338 -0.00577 -0.51 -0.5844 -0.9731 1940008 CBMicro_028760 COc1ccc(cc1)N(CC(=O)NC(C)(C)C)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N23 positive control 0.089 -0.254 -21.07 0.09 -0.254 -22.49 -30.8012 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 N24 positive control 0.094 -0.249 -20.66 0.094 -0.25 -22.13 -30.257 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O01 mock treatment 0.348 0.0052 0.43 0.345 0.00123 0.11 0.3825 0.859 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O02 mock treatment 0.348 0.0052 0.43 0.344 2.33E-4 0.02 0.3199 0.7401 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O03 compound treatment 0.337 -0.0058 -0.48 0.341 -0.00277 -0.25 -0.5139 -0.951 1940009 CBMicro_028761 CC(C)c1ccc(/C=C/C(=O)N2CCN(CC2)c3ccc(F)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O04 compound treatment 0.333 -0.0098 -0.81 0.342 -0.00177 -0.16 -0.686 -0.828 1940010 CBMicro_028762 Cc1c(nc2ccccc2c1C(=O)NCCCc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O05 compound treatment 0.353 0.0102 0.85 0.358 0.0142 1.26 1.4907 0.9812 1451718 CBMicro_028763 Cc1cc(Cl)ccc1OCC(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O06 compound treatment 0.335 -0.0078 -0.65 0.341 -0.00277 -0.25 -0.6313 -0.9117 1940011 CBMicro_028764 COC(=O)c1sc(NC(=O)C(Sc2ccccc2)c3ccccc3)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O07 compound treatment 0.341 -0.0018 -0.15 0.344 2.33E-4 0.02 -0.091 -0.6035 1730733 CBMicro_028765 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CCc2ccc(OC)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O08 compound treatment 0.338 -0.0048 -0.4 0.344 2.33E-4 0.02 -0.2672 -0.6695 1338449 CBMicro_028766 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CCC(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O09 compound treatment 0.344 0.0012 0.1 0.35 0.00623 0.55 0.4611 0.8214 1416799 CBMicro_028767 O=C(NC1CCCCC1)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O10 compound treatment 0.332 -0.0108 -0.9 0.334 -0.00977 -0.87 -1.246 -0.9998 1340739 CBMicro_028768 CN(C)S(=O)(=O)c1cc(c(Cl)cc1N)S(=O)(=O)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O11 compound treatment 0.335 -0.0078 -0.65 0.338 -0.00577 -0.51 -0.8193 -0.9931 1146415 CBMicro_028769 COC(=O)c1sc(NC(=O)C2CCCCC2)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O12 compound treatment 0.338 -0.0048 -0.4 0.345 0.00123 0.11 -0.2045 -0.4949 1642936 CBMicro_028770 COc1ccc(NC(=O)Nc2ccccc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O13 compound treatment 0.344 0.0012 0.1 0.347 0.00323 0.29 0.2731 0.9001 1940012 CBMicro_028771 O=C(N/C(=N\C(=O)c1ccccc1)/Nc2nc3ccccc3o2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O14 compound treatment 0.347 0.0042 0.35 0.347 0.00323 0.29 0.4492 0.9953 1415895 CBMicro_028772 COc1ccc(CCC(=O)NCc2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O15 compound treatment 0.345 0.0022 0.18 0.351 0.00723 0.64 0.5824 0.8738 1940013 CBMicro_028773 COC(=O)c1sccc1NC(=O)/C=C/c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O16 compound treatment 0.358 0.0152 1.26 0.355 0.0112 1.0 1.5962 0.9931 1390365 CBMicro_028774 COC(=O)c1sc(NC(=O)COc2ccc3ccccc3c2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O17 compound treatment 0.334 -0.0088 -0.73 0.344 2.33E-4 0.02 -0.502 -0.6868 1253361 CBMicro_028775 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O18 compound treatment 0.367 0.0242 2.01 0.385 0.0412 3.65 4.0045 0.9603 1940014 CBMicro_028776 Cc1ccc(o1)C(=O)Nc2nc(cs2)c3cccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O19 compound treatment 0.343 2.0E-4 0.02 0.344 2.33E-4 0.02 0.0264 0.9941 1940015 CBMicro_028777 Cc1cccc(N2CCN(CC2)C(=O)CCCOc3ccc(Cl)cc3C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O20 compound treatment 0.359 0.0162 1.34 0.367 0.0232 2.06 2.4069 0.9787 1284418 CBMicro_028778 Cc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccccc3Cl)c4ccccc4)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O21 compound treatment 0.345 0.0022 0.18 0.347 0.00323 0.29 0.3318 0.9763 1599820 CBMicro_028779 Nc1cc(Cl)c(cc1S(=O)(=O)N2CCOCC2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O22 compound treatment 0.847 0.504 41.86 0.838 0.494 43.8 60.5694 0.9997 1940016 CBMicro_028780 NC/1=NNC(=N)\C1=N\Nc2ccccc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O23 positive control 0.09 -0.253 -20.99 0.09 -0.254 -22.49 -30.7425 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 O24 positive control 0.096 -0.247 -20.49 0.094 -0.25 -22.13 -30.1396 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P01 mock treatment 0.341 -0.0018 -0.15 0.342 -0.00177 -0.16 -0.2164 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P02 mock treatment 0.348 0.0052 0.43 0.346 0.00223 0.2 0.4452 0.9375 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P03 compound treatment 0.376 0.0332 2.76 0.379 0.0352 3.12 4.1568 0.9981 1940017 CBMicro_028781 CN1CCC(=NNC(=O)c2cc3ccccc3cc2O)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P04 compound treatment 0.373 0.0302 2.51 0.385 0.0412 3.65 4.3567 0.9831 1485549 CBMicro_028782 COc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P05 compound treatment 0.342 -8.0E-4 -0.07 0.346 0.00223 0.2 0.093 0.4454 1167837 CBMicro_028783 Cc1ccc(cc1)c2cc(C(=O)NCCN3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P06 compound treatment 0.345 0.0022 0.18 0.351 0.00723 0.64 0.5824 0.8738 1940018 CBMicro_028784 Fc1ccc(cc1)N2CCN(CC2)C(=O)/C=C/c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P07 compound treatment 0.268 -0.0748 -6.21 0.347 0.00323 0.29 -4.1884 -0.6738 1294541 CBMicro_028785 COc1ccccc1N2C(=O)c3cccc4c(Cl)ccc(C2=O)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P08 compound treatment 0.34 -0.0028 -0.23 0.342 -0.00177 -0.16 -0.2751 -0.9815 1504285 CBMicro_028786 CCC(Oc1ccccc1)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P09 compound treatment 0.366 0.0232 1.93 0.371 0.0272 2.41 3.0685 0.9938 1940019 CBMicro_028787 COc1ccc(Cl)cc1NC(=O)c2c(C)onc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P10 compound treatment 0.348 0.0052 0.43 0.35 0.00623 0.55 0.6959 0.9926 1940020 CBMicro_028788 CC(C)(C)c1ccc(cc1)C(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P11 compound treatment 0.33 -0.0128 -1.06 0.336 -0.00777 -0.69 -1.2381 -0.9779 1737927 CBMicro_028789 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC(CC(=O)O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P12 compound treatment 0.365 0.0222 1.84 0.38 0.0362 3.21 3.5738 0.9653 1328262 CBMicro_028790 COc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P13 compound treatment 0.344 0.0012 0.1 0.35 0.00623 0.55 0.4611 0.8214 1940021 CBMicro_028791 O=C(COc1ccccc1)NCCCn2ccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P14 compound treatment 0.396 0.0532 4.42 0.382 0.0382 3.39 5.5189 0.9914 1940022 CBMicro_028792 CCOC(=O)CNC(=O)c1cc(nc2ccccc12)c3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P15 compound treatment 0.359 0.0162 1.34 0.381 0.0372 3.3 3.2842 0.9217 1940023 CBMicro_028793 [O-][N+](=O)c1cc(NC(=O)c2ccc3OCOc3c2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P16 compound treatment 0.351 0.0082 0.68 0.36 0.0162 1.44 1.4986 0.9416 1940024 CBMicro_028794 COc1ccc(/C=N/OCC(=O)N\N=C\2/C(=O)N(CN(C)C)c3ccc(Br)cc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P17 compound treatment 0.354 0.0112 0.93 0.367 0.0232 2.06 2.1134 0.9355 1940025 CBMicro_028795 Cc1sc(NC(=O)c2cccs2)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P18 compound treatment 0.343 2.0E-4 0.02 0.337 -0.00677 -0.6 -0.4123 -0.6873 1560909 CBMicro_028796 CCOC(=O)c1c(C)nc2CC(C)(C)CC(=O)c2c1c3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P19 compound treatment 0.34 -0.0028 -0.23 0.351 0.00723 0.64 0.2889 0.4237 1940026 CBMicro_028797 [O-][N+](=O)c1ccc(Cl)cc1C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P20 compound treatment 0.401 0.0582 4.83 0.399 0.0552 4.89 6.8777 1.0 1551867 CBMicro_028798 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(F)cc3)C(=O)OCC4CCCO4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P21 compound treatment 0.341 -0.0018 -0.15 0.344 2.33E-4 0.02 -0.091 -0.6035 1940027 CBMicro_028799 NC(=O)N/N=C(\C1CC1)/c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P22 compound treatment 0.354 0.0112 0.93 0.36 0.0162 1.44 1.6747 0.9777 1940028 CBMicro_028800 O=C/1N\C(=N\c2ccccc2)\S\C1=C\c3ccsc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P23 positive control 0.091 -0.252 -20.9 0.092 -0.252 -22.31 -30.5585 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.775 P24 positive control 0.097 -0.246 -20.41 0.096 -0.248 -21.96 -29.9556 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A01 mock treatment 0.332 -0.00919 -0.76 0.323 -0.0145 -1.28 -1.447 -0.9691 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A02 mock treatment 0.333 -0.00819 -0.68 0.337 -4.84E-4 -0.04 -0.511 -0.7502 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A03 compound treatment 0.319 -0.0222 -1.84 0.317 -0.0205 -1.82 -2.5861 -1.0 1156143 CBMicro_028801 Cc1sc(NC(=O)c2cc(nc3ccccc23)c4cccs4)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A04 compound treatment 0.334 -0.00719 -0.6 0.328 -0.00948 -0.84 -1.0162 -0.9859 1434460 CBMicro_028802 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCC4CCCO4)c(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A05 compound treatment 0.325 -0.0162 -1.34 0.321 -0.0165 -1.46 -1.9832 -0.9991 1409457 CBMicro_028803 COc1ccc(cc1)C(=O)Nc2sc3CCCCCc3c2C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A06 compound treatment 0.317 -0.0242 -2.01 0.315 -0.0225 -1.99 -2.8288 -1.0 1940029 CBMicro_028804 CCOC(=O)c1sc(NC(=O)Nc2cccc(Cl)c2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A07 compound treatment 0.334 -0.00719 -0.6 0.326 -0.0115 -1.02 -1.1416 -0.9676 1727207 CBMicro_028805 CCOc1cc(cc(OCC)c1OCC)C(=O)N2CCc3ccccc3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A08 compound treatment 0.314 -0.0272 -2.26 0.309 -0.0285 -2.52 -3.3809 -0.9984 1655502 CBMicro_028806 Cc1ccc(o1)c2cc(C(=O)Nc3cc(C)on3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A09 compound treatment 0.321 -0.0202 -1.68 0.313 -0.0245 -2.17 -2.7194 -0.9919 1413771 CBMicro_028807 COc1ccccc1N2CCN(CC2)C(=O)C3C(C4CC3C=C4)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A10 compound treatment 0.338 -0.00319 -0.26 0.331 -0.00648 -0.57 -0.5934 -0.9381 1461078 CBMicro_028808 Cc1ccc(o1)c2cc(C(=O)N3CCC(Cc4ccccc4)CC3)c5ccccc5n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A11 compound treatment 0.32 -0.0212 -1.76 0.317 -0.0205 -1.82 -2.5274 -0.9999 1147698 CBMicro_028809 Cc1onc(c1C(=O)NCc2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A12 compound treatment 0.326 -0.0152 -1.26 0.322 -0.0155 -1.37 -1.8619 -0.9991 1136859 CBMicro_028810 CCC1CCc2c(C#N)c(NC(=O)c3cc4ccccc4oc3=O)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A13 compound treatment 0.34 -0.00119 -0.1 0.332 -0.00548 -0.49 -0.4134 -0.8336 1712418 CBMicro_028811 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A14 compound treatment 0.319 -0.0222 -1.84 0.31 -0.0275 -2.44 -3.0248 -0.9905 1323721 CBMicro_028812 CCc1ccccc1NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A15 compound treatment 0.327 -0.0142 -1.18 0.317 -0.0205 -1.82 -2.1165 -0.9781 1702064 CBMicro_028813 CCOC(=O)CSc1nnc2c3ccccc3n(C)c2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A16 compound treatment 0.325 -0.0162 -1.34 0.316 -0.0215 -1.9 -2.2965 -0.9855 1444072 CBMicro_028814 Cc1ccc(NC(=O)C2C(C3C=CC2C4CC43)C(=O)O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A17 compound treatment 0.318 -0.0232 -1.93 0.313 -0.0245 -2.17 -2.8955 -0.9982 1940030 CBMicro_028815 COc1ccccc1NCC(=O)N/N=C/c2ccccc2OCc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A18 compound treatment 0.335 -0.00619 -0.51 0.327 -0.0105 -0.93 -1.0202 -0.961 1940031 CBMicro_028816 Cc1cc(/C=C\2/SC(=S)NC2=O)c(C)n1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A19 compound treatment 0.326 -0.0152 -1.26 0.316 -0.0215 -1.9 -2.2378 -0.98 1731862 CBMicro_028817 CCOc1ccc(cc1)N(CC(=O)NC2CCCCC2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A20 compound treatment 0.324 -0.0172 -1.43 0.317 -0.0205 -1.82 -2.2926 -0.9929 1703966 CBMicro_028818 O=C(N1CCOCC1)c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A21 compound treatment 0.323 -0.0182 -1.51 0.316 -0.0215 -1.9 -2.414 -0.9934 1461930 CBMicro_028819 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(Cl)cc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A22 compound treatment 0.327 -0.0142 -1.18 0.317 -0.0205 -1.82 -2.1165 -0.9781 1490766 CBMicro_028820 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2cc(C)ccc2C)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A23 positive control 0.083 -0.258 -21.43 0.082 -0.255 -22.64 -31.1664 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 A24 positive control 0.085 -0.256 -21.27 0.084 -0.253 -22.46 -30.9236 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B01 mock treatment 0.337 -0.00419 -0.35 0.335 -0.00248 -0.22 -0.4015 -0.9757 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B02 mock treatment 0.341 -1.87E-4 -0.02 0.341 0.00352 0.31 0.2093 0.6709 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B03 compound treatment 0.333 -0.00819 -0.68 0.328 -0.00948 -0.84 -1.0749 -0.9945 1396518 CBMicro_028821 COc1ccc2CN(C(=O)c2c1OC)c3ccc(I)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B04 compound treatment 0.336 -0.00519 -0.43 0.332 -0.00548 -0.49 -0.6482 -0.9982 1613378 CBMicro_028822 C=CCc1cccc2cc(C(=O)NC3=C(CCC3)C#N)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B05 compound treatment 0.335 -0.00619 -0.51 0.325 -0.0125 -1.11 -1.1455 -0.9391 1256740 CBMicro_028823 CCOc1ccc(cc1)N(CC(=O)Nc2cccc(C)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B06 compound treatment 0.332 -0.00919 -0.76 0.326 -0.0115 -1.02 -1.259 -0.9899 1155064 CBMicro_028824 CCOC(=O)C1=C(C)NC(=O)CC1c2ccccc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B07 compound treatment 0.334 -0.00719 -0.6 0.33 -0.00748 -0.66 -0.8909 -0.9986 1658761 CBMicro_028825 Cc1ccc2oc(nc2c1)c3ccc(NC(=O)Cc4ccccc4)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B08 compound treatment 0.349 0.00781 0.65 0.34 0.00252 0.22 0.6163 0.8986 1730424 CBMicro_028826 Cc1ccc2N(C(=O)COc3nc4ccccc4s3)C(C)(C)c5ssc(=S)c5-c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B09 compound treatment 0.334 -0.00719 -0.6 0.325 -0.0125 -1.11 -1.2042 -0.958 1940032 CBMicro_028827 Clc1ccc(cc1)c2nc(=O)[nH]c3ccc(Cl)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B10 compound treatment 0.333 -0.00819 -0.68 0.326 -0.0115 -1.02 -1.2003 -0.9807 1940033 CBMicro_028828 O=C1N(Cc2ccccc12)c3nccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B11 compound treatment 0.347 0.00581 0.48 0.342 0.00452 0.4 0.6242 0.9957 1298178 CBMicro_028829 COc1ccc(cc1)N(CC(=O)N2CCCC2)S(=O)(=O)c3ccc(NC(=O)C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B12 compound treatment 0.336 -0.00519 -0.43 0.332 -0.00548 -0.49 -0.6482 -0.9982 1724674 CBMicro_028830 CCN(CC)C(=O)c1c(C)onc1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B13 compound treatment 0.325 -0.0162 -1.34 0.318 -0.0195 -1.73 -2.1712 -0.9923 1940034 CBMicro_028831 O=C(/C=C/c1ccc(OC2CSC2)cc1)c3ccc4OCCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B14 compound treatment 0.312 -0.0292 -2.42 0.307 -0.0305 -2.7 -3.6237 -0.9985 1454128 CBMicro_028832 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B15 compound treatment 0.447 0.106 8.78 0.44 0.103 9.09 12.6357 0.9999 1188179 CBMicro_028833 CC(C)(C)c1cc(C(C#N)C#N)c(c(O)c1O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B16 compound treatment 0.336 -0.00519 -0.43 0.332 -0.00548 -0.49 -0.6482 -0.9982 1128834 CBMicro_028834 CC(=O)Nc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B17 compound treatment 0.331 -0.0102 -0.85 0.326 -0.0115 -1.02 -1.3177 -0.9958 1167246 CBMicro_028835 Cc1nc2ccccn2c1C(=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B18 compound treatment 0.338 -0.00319 -0.26 0.331 -0.00648 -0.57 -0.5934 -0.9381 1619081 CBMicro_028836 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(C)cc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B19 compound treatment 0.393 0.0518 4.3 0.388 0.0505 4.48 6.2072 0.9998 1940035 CBMicro_028837 CCOc1cc(cc(Cl)c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C(=O)OCCSCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B20 compound treatment 0.32 -0.0212 -1.76 0.313 -0.0245 -2.17 -2.7781 -0.9946 1940036 CBMicro_028838 CCN(CC)c1ccc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B21 compound treatment 0.343 0.00181 0.15 0.339 0.00152 0.13 0.2014 0.9984 1940037 CBMicro_028839 O=C(NCCCCCCNC(=O)c1ccc(CN2CCOCC2)cc1)c3ccc(CN4CCOCC4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B22 compound treatment 0.333 -0.00819 -0.68 0.328 -0.00948 -0.84 -1.0749 -0.9945 1940038 CBMicro_028840 C/C(=C/C(=O)Nc1c(C)n(C)n(c2ccccc2)c1=O)/C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B23 positive control 0.082 -0.259 -21.52 0.083 -0.254 -22.55 -31.1624 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 B24 positive control 0.084 -0.257 -21.35 0.082 -0.255 -22.64 -31.1077 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C01 mock treatment 0.347 0.00581 0.48 0.341 0.00352 0.31 0.5616 0.9776 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C02 mock treatment 0.35 0.00881 0.73 0.352 0.0145 1.29 1.427 0.9642 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C03 compound treatment 0.328 -0.0132 -1.09 0.308 -0.0295 -2.61 -2.6218 -0.9254 1716275 CBMicro_028841 O=C(Nc1nc(cs1)c2ccccc2)C3c4ccccc4Oc5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C04 compound treatment 0.37 0.0288 2.39 0.36 0.0225 2.0 3.1024 0.9959 1733245 CBMicro_028842 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(F)cc4)C(=O)OCC(C)C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C05 compound treatment 0.35 0.00881 0.73 0.319 -0.0185 -1.64 -0.641 -0.3573 1257334 CBMicro_028843 CC(Oc1cccc(Cl)c1)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C06 compound treatment 0.37 0.0288 2.39 0.361 0.0235 2.08 3.165 0.9976 1940039 CBMicro_028844 O=C1N(CC#CCN2CCN(CC2)C(c3ccccc3)c4ccccc4)C(=O)c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C07 compound treatment 0.341 -1.87E-4 -0.02 0.337 -4.84E-4 -0.04 -0.0413 -0.9059 1671999 CBMicro_028845 CS(=O)(=O)c1ccc2nc(NC(=O)c3cc(nc4ccccc34)c5cccc(Br)c5)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C08 compound treatment 0.341 -1.87E-4 -0.02 0.335 -0.00248 -0.22 -0.1667 -0.7552 1488948 CBMicro_028846 Clc1ccc(C(=O)Nc2ccccc2c3nc4ccccc4[nH]3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C09 compound treatment 0.365 0.0238 1.98 0.361 0.0235 2.08 2.8715 0.9997 1561207 CBMicro_028847 COc1ccccc1N2CCN(CC2)C(=O)C(Sc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C10 compound treatment 0.337 -0.00419 -0.35 0.326 -0.0115 -1.02 -0.9655 -0.8977 1221514 CBMicro_028848 CN1CCN(CC1)NC(=O)c2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C11 compound treatment 0.334 -0.00719 -0.6 0.327 -0.0105 -0.93 -1.0789 -0.9771 1450101 CBMicro_028849 COc1ccc(cc1OC)C(=O)Nc2nc(c(C)s2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C12 compound treatment 0.34 -0.00119 -0.1 0.333 -0.00448 -0.4 -0.3507 -0.8566 1940040 CBMicro_028850 Cc1onc(c1C(=O)NCCNc2c(Cl)cccc2[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C13 compound treatment 0.34 -0.00119 -0.1 0.342 0.00452 0.4 0.2133 0.5175 1940041 CBMicro_028851 Cc1occc1C(=O)NNC(=O)Nc2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C14 compound treatment 0.345 0.00381 0.32 0.339 0.00152 0.13 0.3188 0.9272 1185664 CBMicro_028852 COC(=O)C1=C(C)NC(=S)NC1c2ccc(OCC(=O)N3CCCCC3)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C15 compound treatment 0.345 0.00381 0.32 0.338 5.16E-4 0.05 0.2561 0.801 1311275 CBMicro_028853 COc1cc(NC(=O)CCN2C(=O)c3ccccc3C2=O)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C16 compound treatment 0.352 0.0108 0.9 0.342 0.00452 0.4 0.9177 0.9338 1699607 CBMicro_028854 CCCOc1ccc(cc1OC)C2NC(=O)N(C)C(=C2C(=O)OCC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C17 compound treatment 0.334 -0.00719 -0.6 0.333 -0.00448 -0.4 -0.7029 -0.9805 1260245 CBMicro_028855 COC(=O)c1cc(NC(=O)c2cc3ccccc3oc2=O)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C18 compound treatment 0.356 0.0148 1.23 0.352 0.0145 1.29 1.7792 0.9997 1940042 CBMicro_028856 CCOC(=O)C1=C(C)Nc2ccccc2S1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C19 compound treatment 0.603 0.262 21.74 0.603 0.266 23.53 32.0079 0.9992 1940043 CBMicro_028857 CCC(Nc1ccccc1)C(=O)N/N=C/c2cc(ccc2O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C20 compound treatment 0.386 0.0448 3.72 0.378 0.0405 3.59 5.1696 0.9998 1940044 CBMicro_028858 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C21 compound treatment 0.314 -0.0272 -2.26 0.296 -0.0415 -3.68 -4.1956 -0.9726 1486364 CBMicro_028859 Clc1cccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C22 compound treatment 0.346 0.00481 0.4 0.336 -0.00148 -0.13 0.1895 0.4506 1940045 CBMicro_028860 COc1cc(/C=C\2/S/C(=N\c3ccccc3Cl)/NC2=O)ccc1OC(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C23 positive control 0.082 -0.259 -21.52 0.082 -0.255 -22.64 -31.2251 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 C24 positive control 0.084 -0.257 -21.35 0.083 -0.254 -22.55 -31.045 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D01 mock treatment 0.344 0.00281 0.23 0.339 0.00152 0.13 0.2601 0.9656 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D02 mock treatment 0.345 0.00381 0.32 0.341 0.00352 0.31 0.4441 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D03 compound treatment 0.334 -0.00719 -0.6 0.329 -0.00848 -0.75 -0.9536 -0.9934 1940046 CBMicro_028861 CC(=O)c1ccc(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D04 compound treatment 0.332 -0.00919 -0.76 0.328 -0.00948 -0.84 -1.1336 -0.9988 1445999 CBMicro_028862 CC(C1CC1)N2C(=O)C3C4C=CC(C3C2=O)C54CC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D05 compound treatment 0.317 -0.0242 -2.01 0.313 -0.0245 -2.17 -2.9542 -0.9993 1781376 CBMicro_028863 CC(=O)Nc1ccc(cc1)N2C(=O)c3cccc4c(ccc(C2=O)c34)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D06 compound treatment 0.362 0.0208 1.73 0.348 0.0105 0.93 1.8808 0.958 1940047 CBMicro_028864 CC(Nc1ccc(Br)cc1)C(=O)N/N=C/c2cccc(CC=C)c2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D07 compound treatment 0.208 -0.133 -11.06 0.288 -0.0495 -4.39 -10.9195 -0.918 1940048 CBMicro_028865 Cn1cc(/C=C\2/SC(=S)N(C2=O)c3cccc(Cl)c3)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D08 compound treatment 0.394 0.0528 4.38 0.387 0.0495 4.39 6.2032 1.0 1940049 CBMicro_028866 COc1ccc(cc1)c2csc(Nc3ccccc3OC)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D09 compound treatment 0.336 -0.00519 -0.43 0.327 -0.0105 -0.93 -0.9615 -0.9389 1360376 CBMicro_028867 Brc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3cc4ccccc4o3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D10 compound treatment 0.35 0.00881 0.73 0.332 -0.00548 -0.49 0.1737 0.1977 1442107 CBMicro_028868 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccco4)C(=O)c5ccc(Cl)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D11 compound treatment 0.336 -0.00519 -0.43 0.329 -0.00848 -0.75 -0.8362 -0.965 1464144 CBMicro_028869 CCOC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D12 compound treatment 0.411 0.0698 5.8 0.4 0.0625 5.54 8.0158 0.9997 1940050 CBMicro_028870 Cc1c(/C=C/c2nc3ccccc3c(=O)[nH]2)c4ccccc4n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D13 compound treatment 0.331 -0.0102 -0.85 0.317 -0.0205 -1.82 -1.8817 -0.9396 1940051 CBMicro_028871 Oc1ccccc1C(=S)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D14 compound treatment 0.351 0.00981 0.81 0.343 0.00552 0.49 0.9217 0.9702 1534284 CBMicro_028872 COc1ccccc1N2CCN(CC2)C(=S)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D15 compound treatment 0.342 8.13E-4 0.07 0.332 -0.00548 -0.49 -0.296 -0.6032 1940052 CBMicro_028873 CCN1C(=C(C(NC1=O)c2ccccc2[N+](=O)[O-])C(=O)OCCOC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D16 compound treatment 0.35 0.00881 0.73 0.341 0.00352 0.31 0.7377 0.9276 1940053 CBMicro_028874 CC(C)(C)C1C(=O)C(=O)C(=CC1=C(C#N)C#N)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D17 compound treatment 0.354 0.0128 1.06 0.348 0.0105 0.93 1.4111 0.9978 1126209 CBMicro_028875 Cc1cccc(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D18 compound treatment 0.343 0.00181 0.15 0.344 0.00652 0.58 0.5147 0.8626 1940054 CBMicro_028876 O=C(NCCCNC(=O)c1ccc(CN2CCOCC2)cc1)c3ccc(CN4CCOCC4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D19 compound treatment 0.327 -0.0142 -1.18 0.324 -0.0135 -1.19 -1.6778 -1.0 1940055 CBMicro_028877 CC(Nc1cccc2ccccc12)C(=O)N/N=C/c3ccc(C)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D20 compound treatment 0.334 -0.00719 -0.6 0.33 -0.00748 -0.66 -0.8909 -0.9986 1049811 CBMicro_028878 Brc1cccc(c1)c2nnc(o2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D21 compound treatment 0.339 -0.00219 -0.18 0.335 -0.00248 -0.22 -0.2841 -0.9954 1384742 CBMicro_028879 O=C(NCc1ccco1)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D22 compound treatment 0.341 -1.87E-4 -0.02 0.336 -0.00148 -0.13 -0.104 -0.7853 1940056 CBMicro_028880 CCSCCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D23 positive control 0.085 -0.256 -21.27 0.084 -0.253 -22.46 -30.9236 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 D24 positive control 0.086 -0.255 -21.19 0.085 -0.252 -22.38 -30.8023 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E01 mock treatment 0.329 -0.0122 -1.01 0.331 -0.00648 -0.57 -1.1218 -0.9641 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E02 mock treatment 0.348 0.00681 0.57 0.343 0.00552 0.49 0.7456 0.9974 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E03 compound treatment 0.338 -0.00319 -0.26 0.325 -0.0125 -1.11 -0.9694 -0.8522 1622893 CBMicro_028881 COC(=O)c1ccc(NC(=O)c2ccoc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E04 compound treatment 0.413 0.0718 5.96 0.369 0.0315 2.79 6.1906 0.9403 1345756 CBMicro_028882 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OCC(C)C)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E05 compound treatment 0.338 -0.00319 -0.26 0.333 -0.00448 -0.4 -0.4681 -0.9805 1279117 CBMicro_028883 O=C(NC1CCCCC1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E06 compound treatment 0.418 0.0768 6.38 0.38 0.0425 3.77 7.1734 0.9685 1361744 CBMicro_028884 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccccc4)c(OC)c3)C(=O)CC(C2)c5ccc(OC)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E07 compound treatment 0.347 0.00581 0.48 0.338 5.16E-4 0.05 0.3736 0.7707 1940057 CBMicro_028885 CCc1c(C)sc(NC(=O)c2ccc(Cl)cc2Cl)c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E08 compound treatment 0.371 0.0298 2.48 0.356 0.0185 1.64 2.9104 0.9801 1940058 CBMicro_028886 COc1ccc(/C=C\2/NC(=S)NC2=O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E09 compound treatment 0.337 -0.00419 -0.35 0.331 -0.00648 -0.57 -0.6521 -0.971 1121713 CBMicro_028887 Clc1cccc(c1)C(=O)Nc2ncccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E10 compound treatment 0.345 0.00381 0.32 0.349 0.0115 1.02 0.9455 0.8848 1940059 CBMicro_028888 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E11 compound treatment 0.273 -0.0682 -5.66 0.314 -0.0235 -2.08 -5.4744 -0.9077 1678054 CBMicro_028889 OC(=O)C1CCCCC1C(=O)Nc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E12 compound treatment 0.352 0.0108 0.9 0.344 0.00652 0.58 1.0431 0.9772 1548049 CBMicro_028890 COc1cc(cc(Br)c1O)C2NC(=O)N(C)C(=C2C(=O)OC3CCCC3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E13 compound treatment 0.337 -0.00419 -0.35 0.331 -0.00648 -0.57 -0.6521 -0.971 1672089 CBMicro_028891 Cc1ccc(o1)C(=O)Nc2sc3CCCCCc3c2C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E14 compound treatment 0.175 -0.166 -13.8 0.165 -0.172 -15.29 -20.5645 -0.9987 1940060 CBMicro_028892 OC(=O)c1ccc(cc1Cl)N2C(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E15 compound treatment 0.346 0.00481 0.4 0.338 5.16E-4 0.05 0.3149 0.7829 1940061 CBMicro_028893 Cc1cc(NCCCCO)n2c3ccccc3nc2c1C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E16 compound treatment 0.341 -1.87E-4 -0.02 0.329 -0.00848 -0.75 -0.5426 -0.7216 1169926 CBMicro_028894 Cc1ccc(cc1NC(=O)c2cccc3c(Br)cccc23)c4nc5ncccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E17 compound treatment 0.325 -0.0162 -1.34 0.322 -0.0155 -1.37 -1.9206 -0.9999 1450085 CBMicro_028895 COC(=O)c1ccc(NC(=S)NC(=O)c2ccn(C)n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E18 compound treatment 0.412 0.0708 5.88 0.393 0.0555 4.92 7.6359 0.9961 1940062 CBMicro_028896 Oc1c(I)cc(/C=C\2/SC(=S)NC2=O)cc1I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E19 compound treatment 0.345 0.00381 0.32 0.341 0.00352 0.31 0.4441 1.0 1940063 CBMicro_028897 CCOC(=O)C1=C(C)N=C2SCCN2C1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E20 compound treatment 0.33 -0.0112 -0.93 0.334 -0.00348 -0.31 -0.8751 -0.8941 1940064 CBMicro_028898 NS(=O)(=O)c1ccc(N/N=C/2\C(=O)N(N=C2c3ccccc3)c4nc(cs4)c5ccccc5)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E21 compound treatment 0.368 0.0268 2.23 0.369 0.0315 2.79 3.5489 0.9937 1225262 CBMicro_028899 COc1ccc2C(CC(=O)c3cc(F)ccc3O)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E22 compound treatment 0.327 -0.0142 -1.18 0.321 -0.0165 -1.46 -1.8658 -0.9943 1322666 CBMicro_028900 Nc1c2-c3ccccc3C(=O)c4c(Cl)ccc([nH]c1=O)c42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E23 positive control 0.087 -0.254 -21.1 0.082 -0.255 -22.64 -30.9316 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 E24 positive control 0.09 -0.251 -20.85 0.089 -0.248 -22.02 -30.3168 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F01 mock treatment 0.339 -0.00219 -0.18 0.334 -0.00348 -0.31 -0.3467 -0.968 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F02 mock treatment 0.341 -1.87E-4 -0.02 0.335 -0.00248 -0.22 -0.1667 -0.7552 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F03 compound treatment 0.218 -0.123 -10.23 0.241 -0.0965 -8.55 -13.2777 -0.996 1940065 CBMicro_028901 Cn1cc(/C=C\2/SC(=S)N(CC=C)C2=O)c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F04 compound treatment 0.338 -0.00319 -0.26 0.331 -0.00648 -0.57 -0.5934 -0.9381 1185830 CBMicro_028902 O=C(NCc1cccs1)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F05 compound treatment 0.315 -0.0262 -2.17 0.312 -0.0255 -2.26 -3.1342 -0.9998 1155438 CBMicro_028903 COc1cccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F06 compound treatment 0.335 -0.00619 -0.51 0.333 -0.00448 -0.4 -0.6442 -0.9919 1278610 CBMicro_028904 CCOc1ccc(cc1)N(CC(=O)N2CCCCC2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F07 compound treatment 0.337 -0.00419 -0.35 0.33 -0.00748 -0.66 -0.7148 -0.9546 1940066 CBMicro_028905 Brc1cccc2c(cccc12)C(=O)Nc3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F08 compound treatment 0.34 -0.00119 -0.1 0.329 -0.00848 -0.75 -0.6014 -0.793 1220231 CBMicro_028906 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)c4cc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F09 compound treatment 0.364 0.0228 1.89 0.357 0.0195 1.73 2.5621 0.999 1544117 CBMicro_028907 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F10 compound treatment 0.324 -0.0172 -1.43 0.317 -0.0205 -1.82 -2.2926 -0.9929 1542361 CBMicro_028908 CN(C)CCNc1ncnc2n(ncc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F11 compound treatment 0.318 -0.0232 -1.93 0.306 -0.0315 -2.79 -3.3341 -0.9836 1340774 CBMicro_028909 COc1ccccc1NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F12 compound treatment 0.364 0.0228 1.89 0.366 0.0285 2.53 3.1261 0.9899 1940067 CBMicro_028910 CCN1C(=O)/C(=C/c2nc3ccccc3c(=O)n2c4cccc(C)c4)/c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F13 compound treatment 0.365 0.0238 1.98 0.357 0.0195 1.73 2.6209 0.9978 1206373 CBMicro_028911 COc1ccc(NC2SC(=O)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F14 compound treatment 0.335 -0.00619 -0.51 0.327 -0.0105 -0.93 -1.0202 -0.961 1340023 CBMicro_028912 CCc1nccn1S(=O)(=O)c2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F15 compound treatment 0.346 0.00481 0.4 0.338 5.16E-4 0.05 0.3149 0.7829 1940068 CBMicro_028913 Cc1ccc(cc1)S(=O)(=O)N=C2NCN(Cc3ccccc3)CN2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F16 compound treatment 0.348 0.00681 0.57 0.338 5.16E-4 0.05 0.4323 0.7618 1940069 CBMicro_028914 N/C(=N/C(=O)c1ccccc1)/Nc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F17 compound treatment 0.349 0.00781 0.65 0.34 0.00252 0.22 0.6163 0.8986 1940070 CBMicro_028915 COc1ccc(/C(=C\N2CCOCC2)/C#N)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F18 compound treatment 0.386 0.0448 3.72 0.381 0.0435 3.86 5.3576 0.9998 1598990 CBMicro_028916 CCOc1cc(cc(Br)c1O)c2nc3ccccc3c(=O)[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F19 compound treatment 0.32 -0.0212 -1.76 0.309 -0.0285 -2.52 -3.0287 -0.9844 1650582 CBMicro_028917 CCCOc1cccc(NC(=O)c2c(C)onc2c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F20 compound treatment 0.515 0.174 14.43 0.522 0.185 16.35 21.7661 0.9981 1940071 CBMicro_028918 Cn1cc(/C=C\2/S/C(=N\c3ccccc3)/NC2=O)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F21 compound treatment 0.331 -0.0102 -0.85 0.328 -0.00948 -0.84 -1.1923 -1.0 1004968 CBMicro_028919 C(Nc1ncnc2n(ncc12)c3ccccc3)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F22 compound treatment 0.359 0.0178 1.48 0.365 0.0275 2.44 2.77 0.9713 1940072 CBMicro_028920 COc1ccc(/C=N/NC(=O)C(C)Nc2ccc(Cl)cc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F23 positive control 0.089 -0.252 -20.94 0.083 -0.254 -22.55 -30.7515 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 F24 positive control 0.087 -0.254 -21.1 0.086 -0.251 -22.29 -30.6809 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G01 mock treatment 0.333 -0.00819 -0.68 0.326 -0.0115 -1.02 -1.2003 -0.9807 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G02 mock treatment 0.339 -0.00219 -0.18 0.333 -0.00448 -0.4 -0.4094 -0.937 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G03 compound treatment 0.331 -0.0102 -0.85 0.323 -0.0145 -1.28 -1.5057 -0.9795 1940073 CBMicro_028921 Cc1onc(c1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-])c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G04 compound treatment 0.333 -0.00819 -0.68 0.326 -0.0115 -1.02 -1.2003 -0.9807 1940074 CBMicro_028922 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3c4ccccc4cc5ccccc35)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G05 compound treatment 0.344 0.00281 0.23 0.343 0.00552 0.49 0.5108 0.9428 1508047 CBMicro_028923 Cc1onc(c1C(=O)Nc2ccc(I)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G06 compound treatment 0.327 -0.0142 -1.18 0.326 -0.0115 -1.02 -1.5525 -0.9974 1940075 CBMicro_028924 O=C(NC(=S)N1CCOCC1)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G07 compound treatment 0.326 -0.0152 -1.26 0.328 -0.00948 -0.84 -1.4859 -0.9806 1940076 CBMicro_028925 Cc1nc(NC(=O)c2ccc(Cl)cc2[N+](=O)[O-])sc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G08 compound treatment 0.338 -0.00319 -0.26 0.33 -0.00748 -0.66 -0.6561 -0.9188 1563291 CBMicro_028926 CCOc1ccc(cc1)N(CC(=O)Nc2ccccc2OC)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G09 compound treatment 0.356 0.0148 1.23 0.346 0.00852 0.75 1.4032 0.9725 1333432 CBMicro_028927 CCC1CCc2c(C(=O)N)c(NC(=O)c3c(C)onc3c4ccccc4)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G10 compound treatment 0.361 0.0198 1.64 0.345 0.00752 0.67 1.6341 0.9208 1940077 CBMicro_028928 CCOc1ccccc1N2CCN(CC2)C(=O)c3ccc(cc3Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G11 compound treatment 0.323 -0.0182 -1.51 0.317 -0.0205 -1.82 -2.3513 -0.9958 1940078 CBMicro_028929 Clc1c(sc2ccccc12)C(=O)Nc3nncs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G12 compound treatment 0.323 -0.0182 -1.51 0.327 -0.0105 -0.93 -1.7246 -0.9728 1267099 CBMicro_028930 COc1ccc(cc1)c2cc(nc(SC)c2C#N)C3CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G13 compound treatment 0.326 -0.0152 -1.26 0.319 -0.0185 -1.64 -2.0498 -0.9916 1940079 CBMicro_028931 CCOC(=O)c1sc(NC(=O)c2cc(ccc2Cl)[N+](=O)[O-])c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G14 compound treatment 0.341 -1.87E-4 -0.02 0.336 -0.00148 -0.13 -0.104 -0.7853 1158340 CBMicro_028932 CCOc1ccc(cc1)N(CC(=O)Nc2cc(C)ccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G15 compound treatment 0.343 0.00181 0.15 0.333 -0.00448 -0.4 -0.1746 -0.4109 1436016 CBMicro_028933 CC(=O)Nc1ccc(Nc2c3CCCc3c(C#N)c4nc5ccccc5n24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G16 compound treatment 0.216 -0.125 -10.39 0.226 -0.111 -9.88 -14.3351 -0.9997 1940080 CBMicro_028934 CCN(CC)c1ccc(/C=C\2/SC(=S)N(CC=C)C2=O)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G17 compound treatment 0.341 -1.87E-4 -0.02 0.336 -0.00148 -0.13 -0.104 -0.7853 1940081 CBMicro_028935 CCSCCOC(=O)C1=C(C)N(C)C(=O)NC1c2cc3OCOc3cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G18 compound treatment 0.332 -0.00919 -0.76 0.327 -0.0105 -0.93 -1.1963 -0.9952 1504203 CBMicro_028936 Cc1nccn1S(=O)(=O)c2cc(Cl)ccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G19 compound treatment 0.302 -0.0392 -3.25 0.297 -0.0405 -3.59 -4.8374 -0.9988 1940082 CBMicro_028937 Clc1ccccc1CSCCNC(=O)/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G20 compound treatment 0.355 0.0138 1.15 0.352 0.0145 1.29 1.7205 0.9984 1940083 CBMicro_028938 O=C1C(=CNCCN2CCN(CC2)C(=S)Nc3ccccc3)C(=O)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G21 compound treatment 0.333 -0.00819 -0.68 0.33 -0.00748 -0.66 -0.9496 -0.9999 1940084 CBMicro_028939 CCN1C(=O)/C(=C\c2ccccc2Sc3ccc(Cl)cc3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G22 compound treatment 0.322 -0.0192 -1.59 0.32 -0.0175 -1.55 -2.222 -0.9999 1407975 CBMicro_028940 Clc1cccc(NC(=O)c2cccc(NC(=O)c3ccco3)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G23 positive control 0.086 -0.255 -21.19 0.083 -0.254 -22.55 -30.9276 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 G24 positive control 0.09 -0.251 -20.85 0.089 -0.248 -22.02 -30.3168 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H01 mock treatment 0.336 -0.00519 -0.43 0.329 -0.00848 -0.75 -0.8362 -0.965 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H02 mock treatment 0.341 -1.87E-4 -0.02 0.334 -0.00348 -0.31 -0.2293 -0.7418 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H03 compound treatment 0.335 -0.00619 -0.51 0.329 -0.00848 -0.75 -0.8949 -0.9827 1661422 CBMicro_028941 O=C(N1CCCC1)c2ccc(CN3CCOCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H04 compound treatment 0.364 0.0228 1.89 0.348 0.0105 0.93 1.9982 0.9467 1940085 CBMicro_028942 Br/C(=C\c1ccccc1)/C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H05 compound treatment 0.338 -0.00319 -0.26 0.331 -0.00648 -0.57 -0.5934 -0.9381 1940086 CBMicro_028943 Cc1ccc(o1)C(=O)N2CCN(CC2)c3c(Cl)cccc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H06 compound treatment 0.131 -0.21 -17.45 0.135 -0.202 -17.94 -25.0274 -0.9999 1940087 CBMicro_028944 Cn1cc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H07 compound treatment 0.316 -0.0252 -2.09 0.302 -0.0355 -3.14 -3.7022 -0.9803 1669587 CBMicro_028945 Cc1ccoc1C(=O)Nc2ccccc2Oc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H08 compound treatment 0.323 -0.0182 -1.51 0.323 -0.0145 -1.28 -1.9753 -0.9967 1780776 CBMicro_028946 CCOC(=O)C1=C(C)NC(=O)CC1c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H09 compound treatment 0.353 0.0118 0.98 0.343 0.00552 0.49 1.0391 0.9483 1637052 CBMicro_028947 CCOc1ccc(NC(=O)c2cccc3c(Br)cccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H10 compound treatment 0.323 -0.0182 -1.51 0.317 -0.0205 -1.82 -2.3513 -0.9958 1603602 CBMicro_028948 O=C(NCc1ccccc1)c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H11 compound treatment 0.312 -0.0292 -2.42 0.31 -0.0275 -2.44 -3.4357 -1.0 1940088 CBMicro_028949 CN1C(=O)/C(=C\c2ccccc2Sc3ccc(Cl)cc3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H12 compound treatment 0.335 -0.00619 -0.51 0.331 -0.00648 -0.57 -0.7695 -0.9984 1940089 CBMicro_028950 COc1ccc2n(C)c(C)c(/C=C/c3nc4ccccc4c(=O)n3c5cccc(C)c5)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H13 compound treatment 0.352 0.0108 0.9 0.359 0.0215 1.91 1.983 0.9409 1780775 CBMicro_028951 CCOC(=O)C1=C(C)NC(=O)CC1c2cc3OCOc3cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H14 compound treatment 0.346 0.00481 0.4 0.343 0.00552 0.49 0.6282 0.995 1940090 CBMicro_028952 CN(CCCC(=O)O)S(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)N(C)CCCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H15 compound treatment 0.36 0.0188 1.56 0.359 0.0215 1.91 2.4527 0.9951 1584130 CBMicro_028953 COc1ccc(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H16 compound treatment 0.336 -0.00519 -0.43 0.329 -0.00848 -0.75 -0.8362 -0.965 1663778 CBMicro_028954 O=C(NCC1CCCO1)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H17 compound treatment 0.325 -0.0162 -1.34 0.317 -0.0205 -1.82 -2.2339 -0.989 1286688 CBMicro_028955 CCCOc1cccc(NC(=O)c2ccc(C)o2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H18 compound treatment 0.524 0.183 15.18 0.523 0.186 16.44 22.3571 0.9992 1940091 CBMicro_028956 CCOC(=O)C/1=C(C)N(CCOC)C(=O)\C1=C/c2cc(OC)c(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H19 compound treatment 0.321 -0.0202 -1.68 0.325 -0.0125 -1.11 -1.9674 -0.9797 1940092 CBMicro_028957 Clc1cccc(Cl)c1/C=N/NC(=O)CC(=O)NCc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H20 compound treatment 0.336 -0.00519 -0.43 0.327 -0.0105 -0.93 -0.9615 -0.9389 1552279 CBMicro_028958 COc1cc(NC(=O)c2ccc(Cl)c(Cl)c2)c(OC)cc1NC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H21 compound treatment 0.375 0.0338 2.81 0.36 0.0225 2.0 3.3959 0.986 1940093 CBMicro_028959 COc1ccc(/C=C\2/S/C(=N\c3ccccc3Cl)/NC2=O)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H22 compound treatment 0.33 -0.0112 -0.93 0.328 -0.00948 -0.84 -1.2511 -0.9988 1940094 CBMicro_028960 CC(C)OC1N/C(=N\[N+](=O)[O-])/N(C)C1OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H23 positive control 0.088 -0.253 -21.02 0.085 -0.252 -22.38 -30.6849 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 H24 positive control 0.089 -0.252 -20.94 0.09 -0.247 -21.93 -30.3128 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I01 mock treatment 0.35 0.00881 0.73 0.338 5.16E-4 0.05 0.5497 0.7499 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I02 mock treatment 0.349 0.00781 0.65 0.343 0.00552 0.49 0.8043 0.9903 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I03 compound treatment 0.312 -0.0292 -2.42 0.304 -0.0335 -2.97 -3.8117 -0.9949 1940095 CBMicro_028961 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2C(C3CC2C=C3)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I04 compound treatment 0.33 -0.0112 -0.93 0.322 -0.0155 -1.37 -1.627 -0.9819 1940096 CBMicro_028962 Cc1cc2nc(oc2cc1C)c3cc(NC(=O)c4cccc(c4)[N+](=O)[O-])ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I05 compound treatment 0.344 0.00281 0.23 0.336 -0.00148 -0.13 0.0721 0.2691 1399368 CBMicro_028963 CCOC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I06 compound treatment 0.414 0.0728 6.04 0.412 0.0745 6.6 8.9439 0.999 1161372 CBMicro_028964 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccncc4)C(=O)OCCc5ccccc5)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I07 compound treatment 0.364 0.0228 1.89 0.345 0.00752 0.67 1.8102 0.9017 1188570 CBMicro_028965 CN1CCN(CC1)C(=O)c2cc(nc3ccccc23)c4ccc(Cl)c(Cl)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I08 compound treatment 0.374 0.0328 2.72 0.365 0.0275 2.44 3.6505 0.9985 1356931 CBMicro_028966 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I09 compound treatment 0.341 -1.87E-4 -0.02 0.345 0.00752 0.67 0.46 0.6904 1658719 CBMicro_028967 Cc1occc1C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I10 compound treatment 0.343 0.00181 0.15 0.346 0.00852 0.75 0.6401 0.8317 1448632 CBMicro_028968 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I11 compound treatment 0.329 -0.0122 -1.01 0.328 -0.00948 -0.84 -1.3098 -0.9958 1631447 CBMicro_028969 CN(C)CCNC(=O)c1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I12 compound treatment 0.364 0.0228 1.89 0.356 0.0185 1.64 2.4995 0.9974 1940097 CBMicro_028970 O=C(NCc1ccco1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I13 compound treatment 0.336 -0.00519 -0.43 0.332 -0.00548 -0.49 -0.6482 -0.9982 1940098 CBMicro_028971 CCCN1C(=O)C2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I14 compound treatment 0.328 -0.0132 -1.09 0.328 -0.00948 -0.84 -1.3685 -0.9915 1940099 CBMicro_028972 C/C(=C/1\C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2)/NCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I15 compound treatment 0.344 0.00281 0.23 0.333 -0.00448 -0.4 -0.1159 -0.2514 1313972 CBMicro_028973 O=c1n(c2ccccc2)c(nc3ccccc13)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I16 compound treatment 0.382 0.0408 3.39 0.373 0.0355 3.15 4.6214 0.9993 1319731 CBMicro_028974 CC1=C(C(C2=C(CC(CC2=O)c3ccc(Cl)cc3)N1)c4cccc(O)c4)C(=O)OC5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I17 compound treatment 0.367 0.0258 2.14 0.366 0.0285 2.53 3.3022 0.9966 1370411 CBMicro_028975 Clc1ccc(NC(=O)c2cc3ccccc3o2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I18 compound treatment 0.332 -0.00919 -0.76 0.34 0.00252 0.22 -0.3817 -0.4803 1236435 CBMicro_028976 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N2CCOCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I19 compound treatment 0.344 0.00281 0.23 0.339 0.00152 0.13 0.2601 0.9656 1698196 CBMicro_028977 COc1ccc2C(=O)C(Cc2c1)C3(O)C(=O)N(C)c4ccccc43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I20 compound treatment 0.339 -0.00219 -0.18 0.35 0.0125 1.11 0.6559 0.5836 1303449 CBMicro_028978 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(=O)Nc4cccc(Cl)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I21 compound treatment 0.344 0.00281 0.23 0.339 0.00152 0.13 0.2601 0.9656 1250241 CBMicro_028979 COc1ccc(OC)c(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I22 compound treatment 0.366 0.0248 2.06 0.362 0.0245 2.17 2.9929 0.9996 1365489 CBMicro_028980 CC(=O)Nc1ccc(Cl)c(c1)c2nc3cc(C)c(C)cc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I23 positive control 0.085 -0.256 -21.27 0.083 -0.254 -22.55 -30.9863 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 I24 positive control 0.09 -0.251 -20.85 0.088 -0.249 -22.11 -30.3795 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J01 mock treatment 0.323 -0.0182 -1.51 0.307 -0.0305 -2.7 -2.9779 -0.9622 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J02 mock treatment 0.342 8.13E-4 0.07 0.345 0.00752 0.67 0.5187 0.7748 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J03 compound treatment 0.337 -0.00419 -0.35 0.308 -0.0295 -2.61 -2.0934 -0.7942 1555771 CBMicro_028981 CCOC(=O)COc1ccc(cc1OC)C2NC(=S)NC(=C2C(=O)OC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J04 compound treatment 0.349 0.00781 0.65 0.333 -0.00448 -0.4 0.1776 0.2335 1940100 CBMicro_028982 FC(F)(F)c1cc(NC(=O)C(=O)NCc2cccnc2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J05 compound treatment 0.34 -0.00119 -0.1 0.366 0.0285 2.53 1.7173 0.679 1940101 CBMicro_028983 CCOCCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(OCc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J06 compound treatment 0.354 0.0128 1.06 0.348 0.0105 0.93 1.4111 0.9978 1493633 CBMicro_028984 CCOc1ccc(cc1)N(CC(=O)Nc2cc(C)cc(C)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J07 compound treatment 0.355 0.0138 1.15 0.327 -0.0105 -0.93 0.1539 0.1043 1940102 CBMicro_028985 CC(=O)c1cccc(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J08 compound treatment 0.331 -0.0102 -0.85 0.308 -0.0295 -2.61 -2.4457 -0.8905 1234839 CBMicro_028986 CC1=C(C(C2=C(CC(CC2=O)c3ccc(Cl)cc3)N1)c4ccccc4)C(=O)OC5CCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J09 compound treatment 0.329 -0.0122 -1.01 0.323 -0.0145 -1.28 -1.6231 -0.9931 1137816 CBMicro_028987 Cc1cc(NC(=O)c2cc3ccccc3o2)ccc1NC(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J10 compound treatment 0.37 0.0288 2.39 0.36 0.0225 2.0 3.1024 0.9959 1776743 CBMicro_028988 C(/C=C/c1ccccc1)N2CCN(CC2)c3ncnc4n(ncc34)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J11 compound treatment 0.337 -0.00419 -0.35 0.33 -0.00748 -0.66 -0.7148 -0.9546 1455633 CBMicro_028989 O=C(NC1CCCCC1)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J12 compound treatment 0.346 0.00481 0.4 0.345 0.00752 0.67 0.7535 0.9701 1940103 CBMicro_028990 Cc1ccc(cc1)n2c(/C=C\3/C(=O)Nc4ccccc34)nc5ccccc5c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J13 compound treatment 0.34 -0.00119 -0.1 0.395 0.0575 5.1 3.5345 0.6933 1940104 CBMicro_028991 CN1C(=O)/C(=C\c2ccc(cc2)[N+](=O)[O-])/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J14 compound treatment 0.353 0.0118 0.98 0.355 0.0175 1.55 1.7911 0.9755 1940105 CBMicro_028992 CN1C(=C(C(NC1=O)c2ccccc2[N+](=O)[O-])C(=O)OCCOc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J15 compound treatment 0.332 -0.00919 -0.76 0.327 -0.0105 -0.93 -1.1963 -0.9952 1704775 CBMicro_028993 CCOc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3cccc(C)c3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J16 compound treatment 0.371 0.0298 2.48 0.354 0.0165 1.46 2.7851 0.9686 1377591 CBMicro_028994 O=C(C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J17 compound treatment 0.323 -0.0182 -1.51 0.31 -0.0275 -2.44 -2.7899 -0.9736 1553300 CBMicro_028995 CCOc1ccc(cc1)N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J18 compound treatment 0.355 0.0138 1.15 0.348 0.0105 0.93 1.4698 0.9947 1940106 CBMicro_028996 Oc1c(Br)cc(cc1/C=N/Nc2nc3ccccc3[nH]2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J19 compound treatment 0.344 0.00281 0.23 0.347 0.00952 0.84 0.7614 0.8701 1422483 CBMicro_028997 CN(Cc1ccccc1)C(=O)c2ccc(CN3CCc4ccccc4C3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J20 compound treatment 0.343 0.00181 0.15 0.335 -0.00248 -0.22 -0.0493 -0.1847 1940107 CBMicro_028998 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J21 compound treatment 0.354 0.0128 1.06 0.353 0.0155 1.38 1.7245 0.9919 1864113 CBMicro_028999 [O-][N+](=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J22 compound treatment 0.338 -0.00319 -0.26 0.338 5.16E-4 0.05 -0.1548 -0.5763 1711785 CBMicro_029000 CCOC(=O)c1c(C)nc2CC(C)(C)CC(=O)c2c1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J23 positive control 0.086 -0.255 -21.19 0.085 -0.252 -22.38 -30.8023 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 J24 positive control 0.089 -0.252 -20.94 0.088 -0.249 -22.11 -30.4382 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K01 mock treatment 0.34 -0.00119 -0.1 0.335 -0.00248 -0.22 -0.2254 -0.9344 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K02 mock treatment 0.342 8.13E-4 0.07 0.338 5.16E-4 0.05 0.08 0.9821 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K03 compound treatment 0.347 0.00581 0.48 0.343 0.00552 0.49 0.6869 1.0 1440592 CBMicro_029001 CC(C)C(=O)Nc1sc2CCCCCc2c1C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K04 compound treatment 0.369 0.0278 2.31 0.363 0.0255 2.26 3.2317 0.9999 1482466 CBMicro_029002 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4cc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K05 compound treatment 0.359 0.0178 1.48 0.352 0.0145 1.29 1.9553 0.9976 1525626 CBMicro_029003 Cc1onc(c1C(=O)Nc2sc3CCCCc3c2C(=O)N)c4c(Cl)cccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K06 compound treatment 0.34 -0.00119 -0.1 0.339 0.00152 0.13 0.0253 0.1518 1132503 CBMicro_029004 CCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCc4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K07 compound treatment 0.3 -0.0412 -3.42 0.302 -0.0355 -3.14 -4.6414 -0.9991 1940108 CBMicro_029005 [O-][N+](=O)c1cccc(c1)S(=O)(=O)NNc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K08 compound treatment 0.331 -0.0102 -0.85 0.33 -0.00748 -0.66 -1.067 -0.9928 1410033 CBMicro_029006 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K09 compound treatment 0.301 -0.0402 -3.34 0.296 -0.0415 -3.68 -4.9587 -0.9988 1392367 CBMicro_029007 COc1ccccc1NC(=O)C(C)Oc2ccc(Cl)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K10 compound treatment 0.326 -0.0152 -1.26 0.325 -0.0125 -1.11 -1.6739 -0.9979 1940109 CBMicro_029008 CC1(C)Cc2[nH]c(=O)c(C#N)cc2CO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K11 compound treatment 0.263 -0.0782 -6.49 0.184 -0.153 -13.6 -14.2079 -0.9427 1516775 CBMicro_029009 CC1(C)CC(Cc2ccccc2)(CCO1)C(CO)CNCc3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K12 compound treatment 0.488 0.147 12.19 0.489 0.152 13.43 18.1132 0.9988 1249091 CBMicro_029010 COc1ccc2C(CC(=O)c3cc(Cl)ccc3O)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K13 compound treatment 0.348 0.00681 0.57 0.343 0.00552 0.49 0.7456 0.9974 1940110 CBMicro_029011 O=C/1N(Cc2ccccc2)c3ccccc3\C1=C/c4nc5ccccc5c(=O)n4c6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K14 compound treatment 0.364 0.0228 1.89 0.345 0.00752 0.67 1.8102 0.9017 1940111 CBMicro_029012 Clc1ccc(/C=N/NC(=O)Cn2nc3ccccc3n2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K15 compound treatment 0.35 0.00881 0.73 0.335 -0.00248 -0.22 0.3617 0.4734 1940112 CBMicro_029013 Brc1ccc(cc1)n2c(nc3ccccc3c2=O)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K16 compound treatment 0.35 0.00881 0.73 0.344 0.00652 0.58 0.9257 0.9931 1455364 CBMicro_029014 Clc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3cc4ccccc4o3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K17 compound treatment 0.33 -0.0112 -0.93 0.33 -0.00748 -0.66 -1.1257 -0.9864 1314172 CBMicro_029015 CC(C)(C)NC(=O)C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K18 compound treatment 0.325 -0.0162 -1.34 0.321 -0.0165 -1.46 -1.9832 -0.9991 1135905 CBMicro_029016 CCOc1ccccc1NC(=O)c2c(C)onc2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K19 compound treatment 0.331 -0.0102 -0.85 0.328 -0.00948 -0.84 -1.1923 -1.0 1940113 CBMicro_029017 Oc1cnc(Nc2nc3ccccc3s2)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K20 compound treatment 0.324 -0.0172 -1.43 0.33 -0.00748 -0.66 -1.4779 -0.9393 1940114 CBMicro_029018 C/C(=C(/C(=O)C)\c1cc(c(O)c(O)c1C(C)(C)C)C(C)(C)C)/O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K21 compound treatment 0.355 0.0138 1.15 0.359 0.0215 1.91 2.1591 0.9704 1940115 CBMicro_029019 CC(C)(C)c1ccc(cc1)C2=N/C(=C\c3ccc(C#N)cc3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K22 compound treatment 0.343 0.00181 0.15 0.335 -0.00248 -0.22 -0.0493 -0.1847 1940116 CBMicro_029020 NC(=N)NS(=O)(=O)c1ccc(NC(=S)NC(=O)/C=C/c2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K23 positive control 0.088 -0.253 -21.02 0.087 -0.25 -22.2 -30.5595 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 K24 positive control 0.091 -0.25 -20.77 0.09 -0.247 -21.93 -30.1954 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L01 mock treatment 0.346 0.00481 0.4 0.337 -4.84E-4 -0.04 0.2522 0.6276 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L02 mock treatment 0.342 8.13E-4 0.07 0.338 5.16E-4 0.05 0.08 0.9821 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L03 compound treatment 0.35 0.00881 0.73 0.351 0.0135 1.2 1.3643 0.972 1455140 CBMicro_029021 CSc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCCC2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L04 compound treatment 0.348 0.00681 0.57 0.347 0.00952 0.84 0.9962 0.9811 1399555 CBMicro_029022 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccccn4)C(=O)c5ccc(Cl)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L05 compound treatment 0.362 0.0208 1.73 0.355 0.0175 1.55 2.3194 0.9986 1201205 CBMicro_029023 Clc1ccc(NC2SC(=O)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L06 compound treatment 0.337 -0.00419 -0.35 0.331 -0.00648 -0.57 -0.6521 -0.971 1267583 CBMicro_029024 COc1cc(cc(Br)c1O)C2NC(=O)N(C)C(=C2C(=O)OCc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L07 compound treatment 0.355 0.0138 1.15 0.35 0.0125 1.11 1.5952 0.9999 1940117 CBMicro_029025 CC(=O)c1ccc(NC(=O)c2ccc(cc2)N(Cc3ccccc3)S(=O)(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L08 compound treatment 0.326 -0.0152 -1.26 0.325 -0.0125 -1.11 -1.6739 -0.9979 1330784 CBMicro_029026 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(Nc5ccc(C=O)cc5)ccc1c24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L09 compound treatment 0.337 -0.00419 -0.35 0.339 0.00152 0.13 -0.1508 -0.4046 1940118 CBMicro_029027 FC(F)(F)c1cccc(/C=C\2/S/C(=N\c3ccccc3)/NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L10 compound treatment 0.338 -0.00319 -0.26 0.339 0.00152 0.13 -0.0921 -0.3104 1940119 CBMicro_029028 C1CN(CCN1C2c3ccccc3-c4ccccc24)c5ncnc6n(ncc56)c7ccccc7 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L11 compound treatment 0.391 0.0498 4.14 0.381 0.0435 3.86 5.6511 0.9994 1415474 CBMicro_029029 CC1=C(C#N)C(C2=C(CC(CC2=O)c3ccc(Cl)cc3)N1)c4ccc(OCc5ccccc5)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L12 compound treatment 0.348 0.00681 0.57 0.346 0.00852 0.75 0.9336 0.9899 1940120 CBMicro_029030 Cc1ccc(cc1)n2c(/C=C\3/C(=O)Nc4ccc(Br)cc34)nc5ccccc5c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L13 compound treatment 0.349 0.00781 0.65 0.331 -0.00648 -0.57 0.0523 0.0604 1603469 CBMicro_029031 CC(=O)Nc1ccc2oc(nc2c1)c3ccc(F)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L14 compound treatment 0.362 0.0208 1.73 0.354 0.0165 1.46 2.2567 0.9966 1940121 CBMicro_029032 CN1CCN(CC1)c2c([N+](=O)[O-])c(=O)n(C)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L15 compound treatment 0.358 0.0168 1.4 0.353 0.0155 1.38 1.9593 1.0 1940122 CBMicro_029033 CC(=C1C(=O)c2ccccc2C1=O)Nc3ccccc3C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L16 compound treatment 0.338 -0.00319 -0.26 0.34 0.00252 0.22 -0.0294 -0.0851 1258089 CBMicro_029034 Clc1cccc(NC(=O)c2ccc(CN3CCOCC3)cc2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L17 compound treatment 0.227 -0.114 -9.48 0.243 -0.0945 -8.37 -12.624 -0.9981 1940123 CBMicro_029035 COc1ccc(OC)c(/C=C\2/SC(=S)N(C)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L18 compound treatment 0.317 -0.0242 -2.01 0.317 -0.0205 -1.82 -2.7035 -0.9987 1695848 CBMicro_029036 CCOc1ccc(Cc2nnc(S)n2N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L19 compound treatment 0.347 0.00581 0.48 0.349 0.0115 1.02 1.0629 0.9415 1740454 CBMicro_029037 CSc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCOCC2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L20 compound treatment 0.349 0.00781 0.65 0.345 0.00752 0.67 0.9296 0.9999 1940124 CBMicro_029038 C/C(=C(/C(=O)C)\C1=C(C(=O)C(=O)C(=C1)C(C)(C)C)C(C)(C)C)/O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L21 compound treatment 0.347 0.00581 0.48 0.345 0.00752 0.67 0.8122 0.9875 1145695 CBMicro_029039 CN(c1ccc(cc1)C(=O)N2CCCC2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L22 compound treatment 0.338 -0.00319 -0.26 0.329 -0.00848 -0.75 -0.7188 -0.9018 1940125 CBMicro_029040 Cc1ccc(cc1)C2=Nc3ccccc3Nc4c(cc(cc24)[N+](=O)[O-])[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L23 positive control 0.087 -0.254 -21.1 0.086 -0.251 -22.29 -30.6809 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 L24 positive control 0.091 -0.25 -20.77 0.091 -0.246 -21.84 -30.1328 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M01 mock treatment 0.341 -1.87E-4 -0.02 0.335 -0.00248 -0.22 -0.1667 -0.7552 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M02 mock treatment 0.339 -0.00219 -0.18 0.335 -0.00248 -0.22 -0.2841 -0.9954 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M03 compound treatment 0.334 -0.00719 -0.6 0.328 -0.00948 -0.84 -1.0162 -0.9859 1273487 CBMicro_029041 COC(=O)c1sccc1NC(=O)c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M04 compound treatment 0.319 -0.0222 -1.84 0.317 -0.0205 -1.82 -2.5861 -1.0 1196708 CBMicro_029042 Cn1c(=O)c(N2CCOCC2)c3-c4ccccc4C(=O)c5cccc1c53 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M05 compound treatment 0.33 -0.0112 -0.93 0.323 -0.0145 -1.28 -1.5644 -0.9874 1940126 CBMicro_029043 COC(=O)c1cc(NC(=O)CCCOc2ccc(Cl)cc2C)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M06 compound treatment 0.332 -0.00919 -0.76 0.33 -0.00748 -0.66 -1.0083 -0.9976 1466675 CBMicro_029044 COc1ccc2C(=O)N(C(=O)c2c1OC)c3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M07 compound treatment 0.345 0.00381 0.32 0.348 0.0105 0.93 0.8828 0.8969 1319838 CBMicro_029045 CCOc1cc(cc(OCC)c1OCC)C(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M08 compound treatment 0.235 -0.106 -8.82 0.249 -0.0885 -7.84 -11.7784 -0.9983 1940127 CBMicro_029046 Cn1cc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M09 compound treatment 0.362 0.0208 1.73 0.346 0.00852 0.75 1.7554 0.931 1940128 CBMicro_029047 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2ccc(F)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M10 compound treatment 0.33 -0.0112 -0.93 0.333 -0.00448 -0.4 -0.9377 -0.9282 1940129 CBMicro_029048 CC(Nc1ccc(Cl)cc1)C(=O)N/N=C/c2ccc(C)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M11 compound treatment 0.324 -0.0172 -1.43 0.32 -0.0175 -1.55 -2.1046 -0.9992 1342862 CBMicro_029049 CC1CN(C)C(C)CC1NCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M12 compound treatment 0.324 -0.0172 -1.43 0.329 -0.00848 -0.75 -1.5406 -0.9552 1940130 CBMicro_029050 Cc1ccc(cc1)S(=O)(=O)N=C2NCN(CC=C)CN2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M13 compound treatment 0.318 -0.0232 -1.93 0.313 -0.0245 -2.17 -2.8955 -0.9982 1555422 CBMicro_029051 CC1(CNCC2(C)CN(Cc3ccc(Br)cc3)C1)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M14 compound treatment 0.341 -1.87E-4 -0.02 0.335 -0.00248 -0.22 -0.1667 -0.7552 1353854 CBMicro_029052 COc1cc(OC)c(C(=O)N2CC(=O)Nc3ccccc23)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M15 compound treatment 0.349 0.00781 0.65 0.351 0.0135 1.2 1.3056 0.9585 1940131 CBMicro_029053 Cc1cc(C=C2C(=O)NC(=O)NC2=O)c(C)n1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M16 compound treatment 0.32 -0.0212 -1.76 0.32 -0.0175 -1.55 -2.3394 -0.998 1940132 CBMicro_029054 COc1ccc(/C=N/NC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M17 compound treatment 0.331 -0.0102 -0.85 0.328 -0.00948 -0.84 -1.1923 -1.0 1940133 CBMicro_029055 Brc1ccc(/N=C/2\NC(=O)CS2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M18 compound treatment 0.333 -0.00819 -0.68 0.33 -0.00748 -0.66 -0.9496 -0.9999 1940134 CBMicro_029056 CCCOC1NC(=N[N+](=O)[O-])NC1OCCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M19 compound treatment 0.355 0.0138 1.15 0.36 0.0225 2.0 2.2218 0.9654 1940135 CBMicro_029057 C[C@@]12CCC3C(CCC4CCCC[C@@]43C)C2CC[C@@]1(O)CC#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M20 compound treatment 0.329 -0.0122 -1.01 0.323 -0.0145 -1.28 -1.6231 -0.9931 1563200 CBMicro_029058 Oc1ncnc2n(CCOc3ccccc3)ncc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M21 compound treatment 0.558 0.217 18.0 0.542 0.205 18.12 25.5436 1.0 1940136 CBMicro_029059 CCOc1ccc(NCC(=O)N/N=C/c2cc(ccc2O)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M22 compound treatment 0.335 -0.00619 -0.51 0.328 -0.00948 -0.84 -0.9575 -0.9721 1940137 CBMicro_029060 COc1ccc(/N=C/2\NC(=O)CS2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M23 positive control 0.088 -0.253 -21.02 0.086 -0.251 -22.29 -30.6222 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 M24 positive control 0.092 -0.249 -20.69 0.092 -0.245 -21.76 -30.0114 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N01 mock treatment 0.349 0.00781 0.65 0.342 0.00452 0.4 0.7416 0.9731 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N02 mock treatment 0.343 0.00181 0.15 0.339 0.00152 0.13 0.2014 0.9984 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N03 compound treatment 0.235 -0.106 -8.82 0.231 -0.106 -9.44 -12.9064 -0.9994 1940138 CBMicro_029061 CC(C)(C)C1=C/C(=C\c2ccccc2)/C(=C(O)C1=O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N04 compound treatment 0.335 -0.00619 -0.51 0.333 -0.00448 -0.4 -0.6442 -0.9919 1940139 CBMicro_029062 CC1(C)CC(=O)C(=CNCCc2ccc(cc2)S(=O)(=O)N)C(=O)C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N05 compound treatment 0.366 0.0248 2.06 0.357 0.0195 1.73 2.6796 0.9962 1177706 CBMicro_029063 COc1ccccc1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N06 compound treatment 0.336 -0.00519 -0.43 0.335 -0.00248 -0.22 -0.4602 -0.9515 1170556 CBMicro_029064 O=C(C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3)N4CCCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N07 compound treatment 0.344 0.00281 0.23 0.34 0.00252 0.22 0.3228 0.9997 1940140 CBMicro_029065 CCOC(=O)c1cnn(Cc2cccc(Cl)c2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N08 compound treatment 0.313 -0.0282 -2.34 0.309 -0.0285 -2.52 -3.4396 -0.9993 1940141 CBMicro_029066 Clc1ccccc1CSCCNC(=S)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N09 compound treatment 0.365 0.0238 1.98 0.358 0.0205 1.82 2.6835 0.9991 1299432 CBMicro_029067 COc1cccc(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N10 compound treatment 0.361 0.0198 1.64 0.354 0.0165 1.46 2.198 0.9983 1940142 CBMicro_029068 O=C(CSc1nnc[nH]1)n2c3ccccc3c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N11 compound treatment 0.352 0.0108 0.9 0.351 0.0135 1.2 1.4817 0.9899 1195977 CBMicro_029069 C(c1ccccc1)n2ncc3c(ncnc23)N4CCN(CC4)c5ccccn5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N12 compound treatment 0.324 -0.0172 -1.43 0.316 -0.0215 -1.9 -2.3553 -0.9899 1940143 CBMicro_029070 Oc1c(CC=C)cccc1/C=N/NC(=O)CSc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N13 compound treatment 0.334 -0.00719 -0.6 0.329 -0.00848 -0.75 -0.9536 -0.9934 1940144 CBMicro_029071 CC(Nc1cccc2ccccc12)C(=O)N/N=C/c3ccc(O)cc3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N14 compound treatment 0.335 -0.00619 -0.51 0.336 -0.00148 -0.13 -0.4562 -0.8604 1940145 CBMicro_029072 COc1ccc(cc1)C2NC(=S)NC(=C2C(=O)OCCOc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N15 compound treatment 0.341 -1.87E-4 -0.02 0.345 0.00752 0.67 0.46 0.6904 1320499 CBMicro_029073 COc1ccc(OC)c(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N16 compound treatment 0.361 0.0198 1.64 0.347 0.00952 0.84 1.7594 0.9518 1940146 CBMicro_029074 CCOc1ccc2nc(NC(=O)c3ccccc3[N+](=O)[O-])sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N17 compound treatment 0.392 0.0508 4.22 0.395 0.0575 5.1 6.5871 0.9956 1680162 CBMicro_029075 Cc1cc2nc(oc2cc1C)c3cc(NC(=O)c4ccco4)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N18 compound treatment 0.332 -0.00919 -0.76 0.327 -0.0105 -0.93 -1.1963 -0.9952 1672448 CBMicro_029076 CN(Cc1ccccc1)c2nc(C)cc(O)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N19 compound treatment 0.429 0.0878 7.29 0.431 0.0935 8.29 11.0151 0.998 1940147 CBMicro_029077 OC(=O)CN1C(=O)/C(=C\c2ccccc2Sc3ccc(Cl)cc3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N20 compound treatment 0.321 -0.0202 -1.68 0.317 -0.0205 -1.82 -2.4687 -0.9992 1204767 CBMicro_029078 CC(C)COc1ccc(Cc2c(O)nc(S)nc2O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N21 compound treatment 0.342 8.13E-4 0.07 0.341 0.00352 0.31 0.268 0.8407 1002463 CBMicro_029079 CCCCNc1ncnc2n(ncc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N22 compound treatment 0.428 0.0868 7.21 0.423 0.0855 7.58 10.4551 0.9997 1412026 CBMicro_029080 CCN1C(=O)c2cccc3c(NC(=O)c4cccs4)ccc1c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N23 positive control 0.088 -0.253 -21.02 0.087 -0.25 -22.2 -30.5595 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 N24 positive control 0.091 -0.25 -20.77 0.091 -0.246 -21.84 -30.1328 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O01 mock treatment 0.344 0.00281 0.23 0.341 0.00352 0.31 0.3854 0.9899 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O02 mock treatment 0.342 8.13E-4 0.07 0.341 0.00352 0.31 0.268 0.8407 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O03 compound treatment 0.35 0.00881 0.73 0.35 0.0125 1.11 1.3016 0.9796 1940148 CBMicro_029081 Clc1ccc(CC(=O)N2CCN(C/C=C/c3ccccc3)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O04 compound treatment 0.351 0.00981 0.81 0.345 0.00752 0.67 1.047 0.995 1940149 CBMicro_029082 COc1ccc(cc1OC)C(=O)/C=C/c2ccc(OC3CSC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O05 compound treatment 0.344 0.00281 0.23 0.34 0.00252 0.22 0.3228 0.9997 1209049 CBMicro_029083 COC(=O)c1ccccc1NC(=O)c2cnccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O06 compound treatment 0.337 -0.00419 -0.35 0.335 -0.00248 -0.22 -0.4015 -0.9757 1940150 CBMicro_029084 CC(=O)Nc1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O07 compound treatment 0.369 0.0278 2.31 0.363 0.0255 2.26 3.2317 0.9999 1484832 CBMicro_029085 O=C(N1CCN(CC1)c2ccccc2)c3cc(nc4ccccc34)c5cccs5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O08 compound treatment 0.426 0.0848 7.04 0.428 0.0905 8.02 10.651 0.9979 1940151 CBMicro_029086 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O09 compound treatment 0.341 -1.87E-4 -0.02 0.338 5.16E-4 0.05 0.0213 0.4416 1331963 CBMicro_029087 OC(=O)c1ccc2C(=O)N(C(=O)c3cccc1c32)c4cccc5ccccc45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O10 compound treatment 0.329 -0.0122 -1.01 0.325 -0.0125 -1.11 -1.4977 -0.999 1940152 CBMicro_029088 CN1CCN(CC1)C(=S)NC(=O)/C=C/c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O11 compound treatment 0.332 -0.00919 -0.76 0.328 -0.00948 -0.84 -1.1336 -0.9988 1401909 CBMicro_029089 CC1(CN2CC3(C)CN(C1)C42CCCC4)C3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O12 compound treatment 0.344 0.00281 0.23 0.338 5.16E-4 0.05 0.1974 0.8299 243072 CBMicro_029090 O=C(N1CCCCC1)c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O13 compound treatment 0.358 0.0168 1.4 0.359 0.0215 1.91 2.3353 0.9882 1940153 CBMicro_029091 COc1cccc(/C=C/c2nc3ccccc3c(=O)[nH]2)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O14 compound treatment 0.355 0.0138 1.15 0.36 0.0225 2.0 2.2218 0.9654 1940154 CBMicro_029092 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O15 compound treatment 0.352 0.0108 0.9 0.349 0.0115 1.02 1.3564 0.998 1940155 CBMicro_029093 Cc1cc(C=C2C(=O)NC(=S)NC2=O)c(C)n1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O16 compound treatment 0.33 -0.0112 -0.93 0.327 -0.0105 -0.93 -1.3137 -1.0 1940156 CBMicro_029094 CCOc1ccc(NCC(=O)N/N=C/c2c[nH]c3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O17 compound treatment 0.343 0.00181 0.15 0.338 5.16E-4 0.05 0.1387 0.8822 1449239 CBMicro_029095 O=C(Nc1cccc2ccccc12)c3ccc(CN4CCOCC4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O18 compound treatment 0.327 -0.0142 -1.18 0.325 -0.0125 -1.11 -1.6152 -0.9995 1441615 CBMicro_029096 Clc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O19 compound treatment 0.337 -0.00419 -0.35 0.331 -0.00648 -0.57 -0.6521 -0.971 1364220 CBMicro_029097 Cc1c(NC(=O)c2cc3ccccc3o2)cccc1c4nc5ncccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O20 compound treatment 0.338 -0.00319 -0.26 0.332 -0.00548 -0.49 -0.5308 -0.9592 1147896 CBMicro_029098 Ic1ccc(NC(=O)c2ccc(CN3CCOCC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O21 compound treatment 0.421 0.0798 6.63 0.407 0.0695 6.16 9.0415 0.9993 1550627 CBMicro_029099 CC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccccc4Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O22 compound treatment 0.339 -0.00219 -0.18 0.334 -0.00348 -0.31 -0.3467 -0.968 1940157 CBMicro_029100 CC(Nc1ccc(Br)cc1)C(=O)N/N=C/c2ccc(O)cc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O23 positive control 0.087 -0.254 -21.1 0.086 -0.251 -22.29 -30.6809 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 O24 positive control 0.092 -0.249 -20.69 0.091 -0.246 -21.84 -30.0741 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P01 mock treatment 0.343 0.00181 0.15 0.339 0.00152 0.13 0.2014 0.9984 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P02 mock treatment 0.348 0.00681 0.57 0.342 0.00452 0.4 0.6829 0.9857 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P03 compound treatment 0.344 0.00281 0.23 0.343 0.00552 0.49 0.5108 0.9428 1940158 CBMicro_029101 CCC(=O)/N=C(/N)\Nc1nc2ccccc2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P04 compound treatment 0.351 0.00981 0.81 0.342 0.00452 0.4 0.859 0.9465 1732111 CBMicro_029102 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(C)c(C)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P05 compound treatment 0.348 0.00681 0.57 0.338 5.16E-4 0.05 0.4323 0.7618 1425714 CBMicro_029103 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P06 compound treatment 0.332 -0.00919 -0.76 0.33 -0.00748 -0.66 -1.0083 -0.9976 1940159 CBMicro_029104 CC(=O)N/C(=N/C(=O)C)/Nc1nc2ccccc2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P07 compound treatment 0.329 -0.0122 -1.01 0.33 -0.00748 -0.66 -1.1844 -0.979 1940160 CBMicro_029105 CCC(=O)/N=C(\N)/Nc1nc(OC)c2cc(C)ccc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P08 compound treatment 0.33 -0.0112 -0.93 0.323 -0.0145 -1.28 -1.5644 -0.9874 1940161 CBMicro_029106 [O-][N+](=O)c1ccc(/C=C/C(=O)NCCSCc2ccccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P09 compound treatment 0.38 0.0388 3.22 0.373 0.0355 3.15 4.504 0.9999 1940162 CBMicro_029107 Clc1ccc(Sc2ccccc2/C=C\3/SC(=S)NC3=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P10 compound treatment 0.394 0.0528 4.38 0.371 0.0335 2.97 5.2006 0.982 1300823 CBMicro_029108 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)COc4nc5ccccc5s4)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P11 compound treatment 0.33 -0.0112 -0.93 0.334 -0.00348 -0.31 -0.8751 -0.8941 1940163 CBMicro_029109 COCCCNC(=O)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P12 compound treatment 0.336 -0.00519 -0.43 0.327 -0.0105 -0.93 -0.9615 -0.9389 1940164 CBMicro_029110 COc1ccc(CCNC(=O)C(=O)N2CCCCCC2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P13 compound treatment 0.349 0.00781 0.65 0.343 0.00552 0.49 0.8043 0.9903 1140270 CBMicro_029111 CCOC(=O)N1CCN(CC1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P14 compound treatment 0.335 -0.00619 -0.51 0.325 -0.0125 -1.11 -1.1455 -0.9391 1940165 CBMicro_029112 CN(C)C(=O)NCCSCc1ccccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P15 compound treatment 0.338 -0.00319 -0.26 0.331 -0.00648 -0.57 -0.5934 -0.9381 1940166 CBMicro_029113 CC(=O)c1ccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P16 compound treatment 0.343 0.00181 0.15 0.339 0.00152 0.13 0.2014 0.9984 1588101 CBMicro_029114 Clc1cccc(c2nc3cc(NC(=O)c4ccco4)ccc3o2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P17 compound treatment 0.33 -0.0112 -0.93 0.326 -0.0115 -1.02 -1.3764 -0.999 1417897 CBMicro_029115 Cc1nn(Cc2cccc(Cl)c2)c(N)c1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P18 compound treatment 0.356 0.0148 1.23 0.354 0.0165 1.46 1.9045 0.9962 1664584 CBMicro_029116 CC1(C)Cc2c(CO1)sc3nc(c4ccccc4Cl)n(N)c(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P19 compound treatment 0.336 -0.00519 -0.43 0.328 -0.00948 -0.84 -0.8988 -0.9518 1407900 CBMicro_029117 CC(=O)Nc1ccc(cc1)N2C(=O)C3=C(C4CC3C=C4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P20 compound treatment 0.335 -0.00619 -0.51 0.329 -0.00848 -0.75 -0.8949 -0.9827 1940167 CBMicro_029118 CCCNC(=S)N1CC2(C)CN(CC(C)(C1)C2=O)C(=O)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P21 compound treatment 0.341 -1.87E-4 -0.02 0.335 -0.00248 -0.22 -0.1667 -0.7552 1940168 CBMicro_029119 CCOCCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P22 compound treatment 0.346 0.00481 0.4 0.342 0.00452 0.4 0.5655 1.0 1012021 CBMicro_029120 Oc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P23 positive control 0.091 -0.25 -20.77 0.088 -0.249 -22.11 -30.3208 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.776 P24 positive control 0.093 -0.248 -20.6 0.092 -0.245 -21.76 -29.9527 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A01 mock treatment 0.321 -0.0144 -1.19 0.321 -0.018 -1.59 -1.9686 -0.9898 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A02 mock treatment 0.334 -0.00135 -0.11 0.333 -0.00597 -0.53 -0.4534 -0.8388 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A03 compound treatment 0.368 0.0326 2.71 0.361 0.022 1.95 3.2971 0.9871 1725399 CBMicro_029121 Clc1ccccc1C(=O)Nc2ccc(cc2)c3nc4cc(ccc4[nH]3)C(=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A04 compound treatment 0.317 -0.0184 -1.52 0.318 -0.021 -1.86 -2.3914 -0.9951 1940169 CBMicro_029122 Cc1nc(nc(Nc2ccc(Br)cc2)c1C#N)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A05 compound treatment 0.338 0.00265 0.22 0.333 -0.00597 -0.53 -0.2186 -0.3818 1940170 CBMicro_029123 OCCCCNc1c2CCCc2c(C#N)c3nc4ccccc4n13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A06 compound treatment 0.338 0.00265 0.22 0.335 -0.00397 -0.35 -0.0933 -0.2251 1940171 CBMicro_029124 CCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(OCC)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A07 compound treatment 0.351 0.0156 1.3 0.341 0.00203 0.18 1.0458 0.7976 1256150 CBMicro_029125 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A08 compound treatment 0.322 -0.0134 -1.11 0.32 -0.019 -1.68 -1.9725 -0.9796 1158896 CBMicro_029126 CCOc1ccc(cc1)n2c(nc3ccccc3c2=O)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A09 compound treatment 0.31 -0.0254 -2.1 0.313 -0.026 -2.3 -3.1156 -0.999 1940172 CBMicro_029127 COCCNC(=O)C(C)Sc1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A10 compound treatment 0.324 -0.0114 -0.94 0.338 -9.67E-4 -0.09 -0.7271 -0.7682 1940173 CBMicro_029128 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCCSc2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A11 compound treatment 0.332 -0.00335 -0.28 0.33 -0.00897 -0.79 -0.7588 -0.9012 1940174 CBMicro_029129 COc1ccc(CC(=O)Nc2ccc(cc2)C(=O)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A12 compound treatment 0.329 -0.00635 -0.53 0.352 0.013 1.16 0.4437 0.3494 1248479 CBMicro_029130 COc1ccc(OC)c(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(F)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A13 compound treatment 0.336 6.45E-4 0.05 0.337 -0.00197 -0.17 -0.0854 -0.4682 1147568 CBMicro_029131 COc1ccc(cc1OC)c2nnc(o2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A14 compound treatment 0.306 -0.0294 -2.44 0.312 -0.027 -2.39 -3.4131 -1.0 1940175 CBMicro_029132 O=Cc1ccc(o1)c2nc3c4ccccc4ccn3c2C=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A15 compound treatment 0.313 -0.0224 -1.86 0.316 -0.023 -2.04 -2.7515 -0.9989 1526780 CBMicro_029133 CC(C)Oc1ccc(Cc2cnc(N)nc2N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A16 compound treatment 0.346 0.0106 0.88 0.351 0.012 1.07 1.379 0.9956 1940176 CBMicro_029134 CC(=O)Nc1cccc(c1)c2nnc(o2)c3cccc(NC(=O)C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A17 compound treatment 0.327 -0.00835 -0.69 0.331 -0.00797 -0.71 -0.9897 -1.0 1940177 CBMicro_029135 Ic1ccc(NCN2C(=O)S/C(=C/c3ccccc3)/C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A18 compound treatment 0.349 0.0136 1.13 0.344 0.00503 0.45 1.1164 0.917 1167992 CBMicro_029136 Cc1ccc(Cl)cc1NC(=O)c2ccc(cc2)N(Cc3ccccc3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A19 compound treatment 0.319 -0.0164 -1.36 0.323 -0.016 -1.41 -1.9606 -0.9998 1781603 CBMicro_029137 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A20 compound treatment 0.316 -0.0194 -1.61 0.32 -0.019 -1.68 -2.3247 -0.9997 1592263 CBMicro_029138 Cc1ccc(cc1)N(CC(=O)Nc2ccccc2C)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A21 compound treatment 0.314 -0.0214 -1.77 0.313 -0.026 -2.3 -2.8808 -0.9917 1940178 CBMicro_029139 COc1ccc(Cl)cc1NCN2C(=O)S/C(=C/c3ccccc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A22 compound treatment 0.316 -0.0194 -1.61 0.321 -0.018 -1.59 -2.2621 -1.0 1672514 CBMicro_029140 CCOc1ccc(cc1OCC)C(=O)Nc2cc(Cl)ccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A23 positive control 0.083 -0.252 -20.95 0.083 -0.256 -22.68 -30.8542 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 A24 positive control 0.085 -0.25 -20.78 0.086 -0.253 -22.42 -30.5488 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B01 mock treatment 0.33 -0.00535 -0.44 0.33 -0.00897 -0.79 -0.8762 -0.9623 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B02 mock treatment 0.34 0.00465 0.39 0.335 -0.00397 -0.35 0.0241 0.0462 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B03 compound treatment 0.336 6.45E-4 0.05 0.336 -0.00297 -0.26 -0.148 -0.5517 1940179 CBMicro_029141 [O-][N+](=O)c1cnc(Nc2ccc3ccccc3c2)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B04 compound treatment 0.329 -0.00635 -0.53 0.333 -0.00597 -0.53 -0.747 -1.0 1455107 CBMicro_029142 CC1CN(CC(C)O1)C(=O)c2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B05 compound treatment 0.348 0.0126 1.05 0.352 0.013 1.16 1.559 0.9989 1277827 CBMicro_029143 O=C(Cc1ccccc1)Nc2ccc(NC(=O)c3ccco3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B06 compound treatment 0.329 -0.00635 -0.53 0.328 -0.011 -0.97 -1.0603 -0.9588 1175402 CBMicro_029144 COc1cccc2cc(C(=O)Nc3cccc(c3)C(=O)O)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B07 compound treatment 0.315 -0.0204 -1.69 0.326 -0.013 -1.15 -2.0075 -0.9823 1785065 CBMicro_029145 COc1cccc(NC(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B08 compound treatment 0.318 -0.0174 -1.44 0.316 -0.023 -2.04 -2.458 -0.9857 1112982 CBMicro_029146 [O-][N+](=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B09 compound treatment 0.425 0.0896 7.44 0.416 0.077 6.83 10.0898 0.9991 1593775 CBMicro_029147 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)cc3)c(=O)n2C1c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B10 compound treatment 0.359 0.0236 1.96 0.351 0.012 1.07 2.1421 0.9589 1624516 CBMicro_029148 O=C(Nc1nccs1)C2CC2(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B11 compound treatment 0.337 0.00165 0.14 0.33 -0.00897 -0.79 -0.4653 -0.5771 1303398 CBMicro_029149 CC1=CC(C)(C)N(C(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O)c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B12 compound treatment 0.328 -0.00735 -0.61 0.335 -0.00397 -0.35 -0.6803 -0.9656 1537931 CBMicro_029150 Cc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B13 compound treatment 0.36 0.0246 2.05 0.365 0.026 2.31 3.0781 0.9982 1639082 CBMicro_029151 O=C(Nc1cccc(c1)c2nc3ccccc3s2)c4cc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B14 compound treatment 0.332 -0.00335 -0.28 0.337 -0.00197 -0.17 -0.3202 -0.9745 1222866 CBMicro_029152 Cc1ccccc1C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B15 compound treatment 0.345 0.00965 0.8 0.347 0.00803 0.71 1.0696 0.9983 1666786 CBMicro_029153 CC1(C)N(C(=O)COc2nc3ccccc3s2)c4ccccc4-c5c1ssc5=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B16 compound treatment 0.383 0.0476 3.96 0.384 0.045 3.99 5.6189 1.0 1940180 CBMicro_029154 CCC(=O)Nc1nc(cs1)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B17 compound treatment 0.401 0.0656 5.45 0.396 0.057 5.05 7.4276 0.9993 1940181 CBMicro_029155 Cc1cc(N/C=C/C(=O)c2ccc(Cl)s2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B18 compound treatment 0.326 -0.00935 -0.78 0.327 -0.012 -1.06 -1.2991 -0.9883 1569893 CBMicro_029156 Clc1ccc(Cl)c(c1)C(=O)Nc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B19 compound treatment 0.328 -0.00735 -0.61 0.327 -0.012 -1.06 -1.1816 -0.9656 1940182 CBMicro_029157 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)NC2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B20 compound treatment 0.351 0.0156 1.3 0.38 0.041 3.64 3.4898 0.9037 1940183 CBMicro_029158 Nc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B21 compound treatment 0.333 -0.00235 -0.2 0.341 0.00203 0.18 -0.0108 -0.0407 1121413 CBMicro_029159 Cc1onc(c1C(=O)Nc2cccc(Oc3ccccc3)c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B22 compound treatment 0.331 -0.00435 -0.36 0.33 -0.00897 -0.79 -0.8175 -0.9365 1116936 CBMicro_029160 Oc1ccccc1C(=O)Nc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B23 positive control 0.083 -0.252 -20.95 0.086 -0.253 -22.42 -30.6662 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 B24 positive control 0.084 -0.251 -20.87 0.084 -0.255 -22.6 -30.7329 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C01 mock treatment 0.334 -0.00135 -0.11 0.335 -0.00397 -0.35 -0.3281 -0.889 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C02 mock treatment 0.343 0.00765 0.63 0.343 0.00403 0.36 0.7015 0.9631 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C03 compound treatment 0.34 0.00465 0.39 0.348 0.00903 0.8 0.8388 0.9439 1940184 CBMicro_029161 COCCCNC(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C04 compound treatment 0.334 -0.00135 -0.11 0.338 -9.67E-4 -0.09 -0.1401 -0.991 1780839 CBMicro_029162 COc1cc2nc(oc(=O)c2cc1OC)c3ccc([N+](=O)[O-])c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C05 compound treatment 0.333 -0.00235 -0.2 0.335 -0.00397 -0.35 -0.3868 -0.9616 1659807 CBMicro_029163 CCCc1c(C)nc2ccc(NC(=O)C)cc2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C06 compound treatment 0.309 -0.0264 -2.19 0.314 -0.025 -2.21 -3.1117 -1.0 1940185 CBMicro_029164 CN(c1ccc(cc1)C(=O)NCCSCc2cccc(Cl)c2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C07 compound treatment 0.329 -0.00635 -0.53 0.336 -0.00297 -0.26 -0.559 -0.9483 1940186 CBMicro_029165 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)/C=C/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C08 compound treatment 0.328 -0.00735 -0.61 0.33 -0.00897 -0.79 -0.9937 -0.9915 1350001 CBMicro_029166 Fc1ccc(cc1)N(CC(=O)NCc2ccco2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C09 compound treatment 0.366 0.0306 2.54 0.364 0.025 2.22 3.3677 0.9977 1564475 CBMicro_029167 O=C(CSc1nc2ccccc2s1)N3c4ccccc4Sc5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C10 compound treatment 0.323 -0.0124 -1.03 0.324 -0.015 -1.33 -1.6632 -0.9919 1940187 CBMicro_029168 COc1ccc(NC(=O)c2cc(Cl)ccc2Cl)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C11 compound treatment 0.348 0.0126 1.05 0.345 0.00603 0.53 1.1204 0.951 1435047 CBMicro_029169 CN(C)c1cccc(c1)C(=O)Nc2cc(Cl)ccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C12 compound treatment 0.328 -0.00735 -0.61 0.331 -0.00797 -0.71 -0.931 -0.9974 1586178 CBMicro_029170 COc1ccc(cc1)N2C(=O)c3ccccc3C2(O)c4ncc[nH]4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C13 compound treatment 0.315 -0.0204 -1.69 0.319 -0.02 -1.77 -2.4461 -0.9997 1940188 CBMicro_029171 Cc1ccc(OCCNC(C)(C)C)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C14 compound treatment 0.377 0.0416 3.46 0.363 0.024 2.13 3.9508 0.9729 1940189 CBMicro_029172 COC(=O)C/1=C(C)NC(=O)\C1=C/c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C15 compound treatment 0.331 -0.00435 -0.36 0.33 -0.00897 -0.79 -0.8175 -0.9365 1583643 CBMicro_029173 CCOc1ccc(cc1)c2cnc(S)nc2N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C16 compound treatment 0.323 -0.0124 -1.03 0.329 -0.00997 -0.88 -1.3498 -0.9972 1230387 CBMicro_029174 CCN(CC)c1ccc(cc1)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C17 compound treatment 0.318 -0.0174 -1.44 0.318 -0.021 -1.86 -2.3327 -0.9921 1940190 CBMicro_029175 Cc1cc(C)c(OCCCCN2CCCCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C18 compound treatment 0.377 0.0416 3.46 0.371 0.032 2.84 4.4521 0.9952 1135720 CBMicro_029176 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)Nc3ccc(Oc4ccccc4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C19 compound treatment 0.338 0.00265 0.22 0.336 -0.00297 -0.26 -0.0306 -0.0894 1940191 CBMicro_029177 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(cc2)c3nc4cc5ccccc5cc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C20 compound treatment 0.342 0.00665 0.55 0.34 0.00103 0.09 0.4548 0.8134 1940192 CBMicro_029178 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C21 compound treatment 0.342 0.00665 0.55 0.341 0.00203 0.18 0.5175 0.8917 1595093 CBMicro_029179 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N2CCCCCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C22 compound treatment 0.327 -0.00835 -0.69 0.336 -0.00297 -0.26 -0.6764 -0.9118 1940193 CBMicro_029180 CC(NC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(F)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C23 positive control 0.081 -0.254 -21.12 0.082 -0.257 -22.77 -31.0343 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 C24 positive control 0.086 -0.249 -20.7 0.086 -0.253 -22.42 -30.4901 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D01 mock treatment 0.338 0.00265 0.22 0.34 0.00103 0.09 0.22 0.9248 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D02 mock treatment 0.336 6.45E-4 0.05 0.34 0.00103 0.09 0.1026 0.9674 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D03 compound treatment 0.323 -0.0124 -1.03 0.328 -0.011 -0.97 -1.4125 -0.9996 1432919 CBMicro_029181 Nc1ccc(cc1)c2ccc(cc2)N3C(=O)c4cccc5c(ccc(C3=O)c45)C(=O)c6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D04 compound treatment 0.333 -0.00235 -0.2 0.335 -0.00397 -0.35 -0.3868 -0.9616 1568820 CBMicro_029182 CCOc1ccc(cc1)N(CC(=O)NCc2ccccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D05 compound treatment 0.327 -0.00835 -0.69 0.332 -0.00697 -0.62 -0.927 -0.9983 1178350 CBMicro_029183 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(C)cc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D06 compound treatment 0.341 0.00565 0.47 0.344 0.00503 0.45 0.6468 0.9997 1501805 CBMicro_029184 Cc1ccc(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D07 compound treatment 0.357 0.0216 1.8 0.361 0.022 1.95 2.6514 0.9991 1266596 CBMicro_029185 CCCOc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D08 compound treatment 0.337 0.00165 0.14 0.334 -0.00497 -0.44 -0.2147 -0.4658 1046115 CBMicro_029186 CC(=O)C(=Cc1ccccc1O)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D09 compound treatment 0.354 0.0186 1.55 0.354 0.015 1.33 2.0366 0.9972 1575327 CBMicro_029187 COc1ccc2C3CC(=Nc4ccccc4N3C(=O)c2c1OC)c5ccc(Cl)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D10 compound treatment 0.317 -0.0184 -1.52 0.329 -0.00997 -0.88 -1.7021 -0.9664 1940194 CBMicro_029188 C(CCSc1nc2ccccc2o1)CSc3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D11 compound treatment 0.402 0.0666 5.53 0.406 0.067 5.94 8.1129 0.9994 1940195 CBMicro_029189 [O-][N+](=O)c1cc([N+](=O)[O-])c2Nc3ccccc3N=C(c4ccc(Br)cc4)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D12 compound treatment 0.325 -0.0104 -0.86 0.326 -0.013 -1.15 -1.4204 -0.9898 1940196 CBMicro_029190 Clc1ccccc1NC(=O)c2ccccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D13 compound treatment 0.334 -0.00135 -0.11 0.338 -9.67E-4 -0.09 -0.1401 -0.991 1721901 CBMicro_029191 O=C(N1CCN(CC1)S(=O)(=O)c2ccccc2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D14 compound treatment 0.329 -0.00635 -0.53 0.334 -0.00497 -0.44 -0.6843 -0.9959 1394032 CBMicro_029192 Cc1ccccc1OCC(=O)N2CCCc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D15 compound treatment 0.361 0.0256 2.13 0.359 0.02 1.78 2.7608 0.9959 1210826 CBMicro_029193 COc1ccc(CCNC(=O)c2cc3ccccc3oc2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D16 compound treatment 0.335 -3.55E-4 -0.03 0.337 -0.00197 -0.17 -0.1441 -0.8151 1940197 CBMicro_029194 Cc1cc(C)c2nc(NC(=O)c3ccccc3[N+](=O)[O-])sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D17 compound treatment 0.355 0.0196 1.63 0.345 0.00603 0.53 1.5313 0.8922 1501005 CBMicro_029195 COc1ccc(cc1OC)C2N(C(=O)c3ccc(Cl)cc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D18 compound treatment 0.353 0.0176 1.46 0.367 0.028 2.48 2.7925 0.9683 1940198 CBMicro_029196 Cc1ccc(o1)C(=O)N/N=C/c2ccc(o2)c3ccc(Br)cc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D19 compound treatment 0.372 0.0366 3.04 0.364 0.025 2.22 3.7199 0.988 1940199 CBMicro_029197 COc1ccc(/C=C/2\S/C(=N\c3ccc(C)cc3)/N(C2=O)c4ccc(C)cc4)cc1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D20 compound treatment 0.339 0.00365 0.3 0.341 0.00203 0.18 0.3414 0.9693 1940200 CBMicro_029198 N#CCCC1(CCC#N)c2ccccc2-c3ncccc31 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D21 compound treatment 0.333 -0.00235 -0.2 0.333 -0.00597 -0.53 -0.5121 -0.9084 1610052 CBMicro_029199 COC(=O)C1=C(C)NC(=S)NC1c2ccc(OCC(=O)N3CCOCC3)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D22 compound treatment 0.335 -3.55E-4 -0.03 0.339 3.33E-5 0.0 -0.0187 -0.633 1487707 CBMicro_029200 CCc1nnc(NC(=O)C2CC3CCC2C3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D23 positive control 0.082 -0.253 -21.03 0.083 -0.256 -22.68 -30.9129 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 D24 positive control 0.087 -0.248 -20.62 0.088 -0.251 -22.24 -30.3061 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E01 mock treatment 0.328 -0.00735 -0.61 0.331 -0.00797 -0.71 -0.931 -0.9974 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E02 mock treatment 0.335 -3.55E-4 -0.03 0.34 0.00103 0.09 0.0439 0.4566 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E03 compound treatment 0.336 6.45E-4 0.05 0.338 -9.67E-4 -0.09 -0.0227 -0.2247 1940201 CBMicro_029201 Oc1ccccc1C2CC(=NN2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E04 compound treatment 0.313 -0.0224 -1.86 0.314 -0.025 -2.21 -2.8768 -0.9962 1498822 CBMicro_029202 CCOC(=O)c1ccccc1NC(=O)CC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E05 compound treatment 0.327 -0.00835 -0.69 0.327 -0.012 -1.06 -1.2403 -0.9788 1507762 CBMicro_029203 Cc1ccc(cc1NC(=O)CN2C(=O)c3ccccc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E06 compound treatment 0.195 -0.14 -11.65 0.198 -0.141 -12.49 -17.073 -0.9994 1940202 CBMicro_029204 Brc1ccc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E07 compound treatment 0.328 -0.00735 -0.61 0.323 -0.016 -1.41 -1.4323 -0.9294 1940203 CBMicro_029205 CN(C)CCCNC(=O)c1ccc(NC(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E08 compound treatment 0.332 -0.00335 -0.28 0.331 -0.00797 -0.71 -0.6962 -0.9173 1579560 CBMicro_029206 CCOc1ccc(cc1)N(CC(=O)Nc2c(C)cccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E09 compound treatment 0.319 -0.0164 -1.36 0.312 -0.027 -2.39 -2.65 -0.9641 1940204 CBMicro_029207 CC(C)(C)NCCOc1ccc(Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E10 compound treatment 0.32 -0.0154 -1.27 0.327 -0.012 -1.06 -1.6513 -0.9958 1940205 CBMicro_029208 COc1cc(OC)c(NS(=O)(=O)c2ccc(F)cc2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E11 compound treatment 0.293 -0.0424 -3.52 0.316 -0.023 -2.04 -3.9256 -0.9662 1940206 CBMicro_029209 CCOC(=O)C1=C(C)N(C(=S)NC1c2ccc(OC)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E12 compound treatment 0.344 0.00865 0.72 0.349 0.01 0.89 1.1362 0.9944 1133888 CBMicro_029210 CC1CCN(CC1)C(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E13 compound treatment 0.346 0.0106 0.88 0.337 -0.00197 -0.17 0.5017 0.5569 1711928 CBMicro_029211 CC(=O)Nc1ccc(cc1)C(=O)N2CCC(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E14 compound treatment 0.336 6.45E-4 0.05 0.336 -0.00297 -0.26 -0.148 -0.5517 1940207 CBMicro_029212 CCOc1ccccc1NC(=O)c2cc(cc(c2)[N+](=O)[O-])C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E15 compound treatment 0.34 0.00465 0.39 0.341 0.00203 0.18 0.4001 0.94 1940208 CBMicro_029213 O=c1[nH]c(SCC#C)nc2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E16 compound treatment 0.323 -0.0124 -1.03 0.326 -0.013 -1.15 -1.5378 -0.9984 1940209 CBMicro_029214 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(Br)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E17 compound treatment 0.363 0.0276 2.3 0.368 0.029 2.57 3.4422 0.9984 1940210 CBMicro_029215 CCOc1ccc(/C=C/2\S/C(=N\Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E18 compound treatment 0.315 -0.0204 -1.69 0.332 -0.00697 -0.62 -1.6315 -0.9068 1940211 CBMicro_029216 CC(C)(C)NCCOc1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E19 compound treatment 0.329 -0.00635 -0.53 0.327 -0.012 -1.06 -1.1229 -0.948 1557589 CBMicro_029217 CC(Nc1cc(=O)n(C)c(=O)[nH]1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E20 compound treatment 0.346 0.0106 0.88 0.344 0.00503 0.45 0.9403 0.9499 1940212 CBMicro_029218 COc1ccc(N(CC(=O)NC(C)(C)C)S(=O)(=O)c2ccccc2[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E21 compound treatment 0.347 0.0116 0.97 0.348 0.00903 0.8 1.2497 0.9956 1940213 CBMicro_029219 [O-][N+](=O)c1ccc(cc1)c2ccc(o2)C(=S)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E22 compound treatment 0.335 -3.55E-4 -0.03 0.334 -0.00497 -0.44 -0.3321 -0.7527 1271895 CBMicro_029220 Clc1cccc(Cl)c1C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E23 positive control 0.085 -0.25 -20.78 0.083 -0.256 -22.68 -30.7368 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 E24 positive control 0.089 -0.246 -20.45 0.09 -0.249 -22.06 -30.0634 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F01 mock treatment 0.332 -0.00335 -0.28 0.334 -0.00497 -0.44 -0.5082 -0.9756 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F02 mock treatment 0.333 -0.00235 -0.2 0.339 3.33E-5 0.0 -0.1361 -0.6963 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F03 compound treatment 0.322 -0.0134 -1.11 0.331 -0.00797 -0.71 -1.2832 -0.9763 1940214 CBMicro_029221 Cc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)c(C)n1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F04 compound treatment 0.343 0.00765 0.63 0.339 3.33E-5 0.0 0.4509 0.7104 1211448 CBMicro_029222 CCOc1ccc(cc1OCC)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F05 compound treatment 0.276 -0.0594 -4.93 0.282 -0.057 -5.05 -7.0541 -0.9999 1576669 CBMicro_029223 COCc1cc(c(O)c(O)c1C(C)(C)C)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F06 compound treatment 0.319 -0.0164 -1.36 0.325 -0.014 -1.24 -1.8353 -0.9989 1145175 CBMicro_029224 Fc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F07 compound treatment 0.324 -0.0114 -0.94 0.332 -0.00697 -0.62 -1.1031 -0.9789 1940215 CBMicro_029225 FC(F)(F)c1cc(NC(=O)C(=O)NCC2CCCO2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F08 compound treatment 0.329 -0.00635 -0.53 0.327 -0.012 -1.06 -1.1229 -0.948 1033137 CBMicro_029226 CC(=O)Nc1cc(cc(c1)C(=O)O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F09 compound treatment 0.369 0.0336 2.79 0.362 0.023 2.04 3.4185 0.9881 1411938 CBMicro_029227 CC(C)OC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F10 compound treatment 0.351 0.0156 1.3 0.361 0.022 1.95 2.2991 0.9804 1940216 CBMicro_029228 Cc1ccc(cc1)C(=O)NC(NC(=S)Nc2ccccc2Cl)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F11 compound treatment 0.335 -3.55E-4 -0.03 0.333 -0.00597 -0.53 -0.3947 -0.7453 1259112 CBMicro_029229 COc1ccccc1c2nc3ccccc3nc2c4ccccc4OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F12 compound treatment 0.326 -0.00935 -0.78 0.331 -0.00797 -0.71 -1.0484 -0.9989 1940217 CBMicro_029230 Cc1ccc(NC(=O)c2ccccc2Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F13 compound treatment 0.347 0.0116 0.97 0.35 0.011 0.98 1.375 1.0 1186632 CBMicro_029231 CCN(CC)c1ccc(cc1)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F14 compound treatment 0.341 0.00565 0.47 0.351 0.012 1.07 1.0855 0.9318 1679286 CBMicro_029232 CC(C)c1ccc(OC(=O)CCN2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F15 compound treatment 0.362 0.0266 2.21 0.362 0.023 2.04 3.0075 0.9992 1410771 CBMicro_029233 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(SC)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F16 compound treatment 0.414 0.0786 6.53 0.427 0.088 7.8 10.1333 0.9961 1940218 CBMicro_029234 CCOC(=O)c1c(C)c(C)sc1NC(=S)NC(=O)Cc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F17 compound treatment 0.336 6.45E-4 0.05 0.337 -0.00197 -0.17 -0.0854 -0.4682 1327047 CBMicro_029235 CCOC(=O)c1ccc(cc1)N2C(=O)c3cccc4c(ccc(C2=O)c34)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F18 compound treatment 0.349 0.0136 1.13 0.344 0.00503 0.45 1.1164 0.917 1940219 CBMicro_029236 Cc1ccc(cc1N2C(=O)c3ccc(Oc4cccc(c4)[N+](=O)[O-])cc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F19 compound treatment 0.343 0.00765 0.63 0.336 -0.00297 -0.26 0.2629 0.3827 1680923 CBMicro_029237 CC1=CC(C)(C)N(C(=O)COc2nc3ccccc3s2)c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F20 compound treatment 0.351 0.0156 1.3 0.354 0.015 1.33 1.8605 0.9999 1066060 CBMicro_029238 CN1C(CC(=NO)CC1c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F21 compound treatment 0.428 0.0926 7.69 0.426 0.087 7.71 10.8925 1.0 1940220 CBMicro_029239 NC(=S)N1N=C(/C(=N\Nc2ccc(cc2)C(=O)O)/C1=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F22 compound treatment 0.323 -0.0124 -1.03 0.33 -0.00897 -0.79 -1.2872 -0.992 1255560 CBMicro_029240 Cc1ccc(NC(=O)c2cccc(C)c2)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F23 positive control 0.084 -0.251 -20.87 0.088 -0.251 -22.24 -30.4822 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 F24 positive control 0.088 -0.247 -20.54 0.089 -0.25 -22.15 -30.1847 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G01 mock treatment 0.33 -0.00535 -0.44 0.331 -0.00797 -0.71 -0.8136 -0.9751 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G02 mock treatment 0.329 -0.00635 -0.53 0.333 -0.00597 -0.53 -0.747 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G03 compound treatment 0.339 0.00365 0.3 0.352 0.013 1.16 1.0307 0.8632 1940221 CBMicro_029241 O=C1C(C(=O)c2ccccc12)C3=CC(C(N=N3)c4ccccc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G04 compound treatment 0.318 -0.0174 -1.44 0.32 -0.019 -1.68 -2.2073 -0.9971 1940222 CBMicro_029242 CC(C)(C)NCCOc1cccc(Cl)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G05 compound treatment 0.323 -0.0124 -1.03 0.328 -0.011 -0.97 -1.4125 -0.9996 1660896 CBMicro_029243 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(cc3)C(=O)Nc4cccc(O)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G06 compound treatment 0.323 -0.0124 -1.03 0.321 -0.018 -1.59 -1.8512 -0.9774 1651226 CBMicro_029244 Cc1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G07 compound treatment 0.312 -0.0234 -1.94 0.327 -0.012 -1.06 -2.1209 -0.9597 1379497 CBMicro_029245 Clc1cccc(c1)N2CCN(CC2)C(=O)c3c(Cl)cccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G08 compound treatment 0.311 -0.0244 -2.02 0.329 -0.00997 -0.88 -2.0543 -0.931 1940223 CBMicro_029246 CC(C)CNC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G09 compound treatment 0.322 -0.0134 -1.11 0.324 -0.015 -1.33 -1.7219 -0.996 1147685 CBMicro_029247 COc1ccc(NC(=O)c2ccc(NC(=O)C)cc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G10 compound treatment 0.359 0.0236 1.96 0.379 0.04 3.55 3.8967 0.961 1702560 CBMicro_029248 CCOc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4cccc(F)c4)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G11 compound treatment 0.33 -0.00535 -0.44 0.329 -0.00997 -0.88 -0.9389 -0.9495 1597762 CBMicro_029249 COc1ccccc1CC(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G12 compound treatment 0.305 -0.0304 -2.52 0.309 -0.03 -2.66 -3.6598 -0.9997 1940224 CBMicro_029250 Cc1cc(Cl)c(OCCCN2CCCCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G13 compound treatment 0.342 0.00665 0.55 0.341 0.00203 0.18 0.5175 0.8917 1137327 CBMicro_029251 Cc1ccc(cc1)N2CCN(CC2)C(=O)Nc3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G14 compound treatment 0.326 -0.00935 -0.78 0.329 -0.00997 -0.88 -1.1737 -0.9979 1940225 CBMicro_029252 [O-][N+](=O)c1ccc(cc1)c2ccc(cc2)N3C(=O)c4ccc(cc4C3=O)c5nc6ccccc6c(=O)o5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G15 compound treatment 0.332 -0.00335 -0.28 0.339 3.33E-5 0.0 -0.1949 -0.6996 1940226 CBMicro_029253 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2cc(ccc2Cl)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G16 compound treatment 0.35 0.0146 1.22 0.358 0.019 1.69 2.0524 0.9871 1657503 CBMicro_029254 COC(=O)c1ccccc1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G17 compound treatment 0.334 -0.00135 -0.11 0.337 -0.00197 -0.17 -0.2028 -0.9775 1206781 CBMicro_029255 Cc1c(NC(=O)c2ccccc2N(Cc3ccccc3)S(=O)(=O)C)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G18 compound treatment 0.34 0.00465 0.39 0.34 0.00103 0.09 0.3374 0.8513 1672223 CBMicro_029256 COc1ccccc1N2CCN(CC2)C(=O)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G19 compound treatment 0.339 0.00365 0.3 0.34 0.00103 0.09 0.2787 0.8816 1441223 CBMicro_029257 CC(=O)Oc1cc(cc(c1)c2nc3ccccc3c(=O)o2)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G20 compound treatment 0.353 0.0176 1.46 0.357 0.018 1.6 2.1659 0.9991 1940227 CBMicro_029258 COC(=O)c1ccccc1NC(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G21 compound treatment 0.336 6.45E-4 0.05 0.337 -0.00197 -0.17 -0.0854 -0.4682 1310382 CBMicro_029259 CC(=O)Nc1ccc(cc1)C(=O)N2CCCc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G22 compound treatment 0.336 6.45E-4 0.05 0.335 -0.00397 -0.35 -0.2107 -0.5925 1781762 CBMicro_029260 COc1ccc(N(CC(=O)N2CCOCC2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G23 positive control 0.084 -0.251 -20.87 0.086 -0.253 -22.42 -30.6075 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 G24 positive control 0.09 -0.245 -20.37 0.093 -0.246 -21.8 -29.8167 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H01 mock treatment 0.332 -0.00335 -0.28 0.335 -0.00397 -0.35 -0.4455 -0.9934 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H02 mock treatment 0.331 -0.00435 -0.36 0.337 -0.00197 -0.17 -0.3789 -0.944 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H03 compound treatment 0.32 -0.0154 -1.27 0.328 -0.011 -0.97 -1.5886 -0.991 1226394 CBMicro_029261 CCOC(=O)C1=C(C)NC(=O)CC1c2ccccc2I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H04 compound treatment 0.32 -0.0154 -1.27 0.315 -0.024 -2.12 -2.4033 -0.9702 1204596 CBMicro_029262 COc1ccc(cc1)C(=O)Nc2cccc(c2)C(=O)Nc3cccc(O)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H05 compound treatment 0.339 0.00365 0.3 0.345 0.00603 0.53 0.5921 0.9637 1940228 CBMicro_029263 Nc1ccc2oc(nc2c1)c3cccc4c(Br)cccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H06 compound treatment 0.321 -0.0144 -1.19 0.318 -0.021 -1.86 -2.1566 -0.977 1940229 CBMicro_029264 OCCNCCOc1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H07 compound treatment 0.33 -0.00535 -0.44 0.325 -0.014 -1.24 -1.1896 -0.9045 1940230 CBMicro_029265 CCOc1ccc(NCC(=O)N/N=C/c2cccc(c2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H08 compound treatment 0.314 -0.0214 -1.77 0.318 -0.021 -1.86 -2.5675 -0.9997 1940231 CBMicro_029266 Cc1c(NC(=O)/C=C\C(=O)O)c(=O)n(c2ccccc2)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H09 compound treatment 0.318 -0.0174 -1.44 0.323 -0.016 -1.41 -2.0193 -1.0 1332423 CBMicro_029267 CCOC(=O)C1=C(C)NC(=O)CC1c2cc3OCOc3cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H10 compound treatment 0.344 0.00865 0.72 0.357 0.018 1.6 1.6376 0.9347 1940232 CBMicro_029268 CCOc1ccc(NC(=S)NC(NC(=O)c2ccccc2)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H11 compound treatment 0.318 -0.0174 -1.44 0.327 -0.012 -1.06 -1.7687 -0.9886 1940233 CBMicro_029269 CCSCCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H12 compound treatment 0.317 -0.0184 -1.52 0.323 -0.016 -1.41 -2.078 -0.9993 1487286 CBMicro_029270 COC(=O)c1cccc(NC(=O)c2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H13 compound treatment 0.342 0.00665 0.55 0.343 0.00403 0.36 0.6428 0.9779 1940234 CBMicro_029271 CN(c1ccc(cc1)C(=O)NCc2ccccc2C)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H14 compound treatment 0.32 -0.0154 -1.27 0.326 -0.013 -1.15 -1.7139 -0.9987 1439649 CBMicro_029272 CC1CCN(CC1)S(=O)(=O)c2cccc3cccnc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H15 compound treatment 0.331 -0.00435 -0.36 0.339 3.33E-5 0.0 -0.2536 -0.7013 1717532 CBMicro_029273 NNC(=O)COc1ccc2CCCCc2c1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H16 compound treatment 0.364 0.0286 2.38 0.373 0.034 3.02 3.8143 0.9931 1781225 CBMicro_029274 CCOc1ccc2nc(SCC(=O)c3cccc(c3)[N+](=O)[O-])sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H17 compound treatment 0.364 0.0286 2.38 0.356 0.017 1.51 2.749 0.9759 1367389 CBMicro_029275 Nc1ccc(cc1)c2ccc(cc2)N3C(=O)c4cccc5c(Cl)ccc(C3=O)c45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H18 compound treatment 0.324 -0.0114 -0.94 0.324 -0.015 -1.33 -1.6045 -0.986 1940235 CBMicro_029276 Cc1ccc(c(C)c1N2CCc3cn[nH]c23)S(=O)(=O)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H19 compound treatment 0.398 0.0626 5.2 0.398 0.059 5.23 7.3768 1.0 1940236 CBMicro_029277 CN(C)c1ccc(/C=N/NC(=O)c2ccco2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H20 compound treatment 0.349 0.0136 1.13 0.347 0.00803 0.71 1.3044 0.9749 1940237 CBMicro_029278 FC(F)(F)c1cccc(c1)N2C(=O)C3C(C4C=CC3C5CC54)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H21 compound treatment 0.33 -0.00535 -0.44 0.336 -0.00297 -0.26 -0.5003 -0.9686 1203250 CBMicro_029279 CC(=O)Nc1ccc2oc(nc2c1)c3cccc4c(Br)cccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H22 compound treatment 0.328 -0.00735 -0.61 0.331 -0.00797 -0.71 -0.931 -0.9974 1940238 CBMicro_029280 Cc1cccc(NC(=O)c2cc(ccc2Cl)[N+](=O)[O-])c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H23 positive control 0.084 -0.251 -20.87 0.086 -0.253 -22.42 -30.6075 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 H24 positive control 0.091 -0.244 -20.29 0.092 -0.247 -21.89 -29.8206 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I01 mock treatment 0.339 0.00365 0.3 0.345 0.00603 0.53 0.5921 0.9637 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I02 mock treatment 0.338 0.00265 0.22 0.342 0.00303 0.27 0.3454 0.995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I03 compound treatment 0.359 0.0236 1.96 0.363 0.024 2.13 2.8941 0.9992 1940239 CBMicro_029281 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCCSCc2ccccc2Cl)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I04 compound treatment 0.332 -0.00335 -0.28 0.331 -0.00797 -0.71 -0.6962 -0.9173 1549210 CBMicro_029282 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I05 compound treatment 0.662 0.327 27.12 0.64 0.301 26.68 38.0394 1.0 1940240 CBMicro_029283 OC(=O)CN1C(=O)/C(=C\c2ccccc2OCc3ccccc3)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I06 compound treatment 0.357 0.0216 1.8 0.347 0.00803 0.71 1.7741 0.9178 1730823 CBMicro_029284 CCN(CC)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I07 compound treatment 0.322 -0.0134 -1.11 0.326 -0.013 -1.15 -1.5965 -0.9998 1420021 CBMicro_029285 CCOc1cc(C=O)cc(Br)c1OCc2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I08 compound treatment 0.33 -0.00535 -0.44 0.326 -0.013 -1.15 -1.1269 -0.9146 1343138 CBMicro_029286 CS(=O)(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I09 compound treatment 0.325 -0.0104 -0.86 0.336 -0.00297 -0.26 -0.7938 -0.883 1571732 CBMicro_029287 CCN1CCN(CC1)C(=O)C2(C)CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I10 compound treatment 0.319 -0.0164 -1.36 0.316 -0.023 -2.04 -2.3993 -0.9806 1940241 CBMicro_029288 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I11 compound treatment 0.326 -0.00935 -0.78 0.344 0.00503 0.45 -0.2337 -0.261 1940242 CBMicro_029289 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I12 compound treatment 0.211 -0.124 -10.32 0.236 -0.103 -9.13 -13.7525 -0.9981 1940243 CBMicro_029290 [O-][N+](=O)c1ccc(cc1)N2C(=O)/C(=C/c3ccc(I)o3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I13 compound treatment 0.833 0.498 41.31 0.805 0.466 41.3 58.4174 1.0 1940244 CBMicro_029291 CCOc1ccc(/C=C\2/SC(=S)N(CN3CCOCC3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I14 compound treatment 0.364 0.0286 2.38 0.38 0.041 3.64 4.2529 0.9788 1940245 CBMicro_029292 COc1cc(/C=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc(Br)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I15 compound treatment 0.337 0.00165 0.14 0.338 -9.67E-4 -0.09 0.036 0.2233 1940246 CBMicro_029293 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)N[C@@H]3C[C@H]4CC[C@@H]3C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I16 compound treatment 0.31 -0.0254 -2.1 0.311 -0.028 -2.48 -3.2409 -0.9967 1940247 CBMicro_029294 CCCCNCCOc1cccc(Cl)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I17 compound treatment 0.338 0.00265 0.22 0.341 0.00203 0.18 0.2827 0.9952 1940248 CBMicro_029295 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCCC(C)C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I18 compound treatment 0.332 -0.00335 -0.28 0.335 -0.00397 -0.35 -0.4455 -0.9934 1940249 CBMicro_029296 Sc1nnc(c2cccnc2)n1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I19 compound treatment 0.339 0.00365 0.3 0.341 0.00203 0.18 0.3414 0.9693 1584275 CBMicro_029297 OC(=O)c1cc(NC(=O)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I20 compound treatment 0.339 0.00365 0.3 0.343 0.00403 0.36 0.4667 0.9966 1092196 CBMicro_029298 Cn1c(NCc2ccccc2)cc(=O)n(C)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I21 compound treatment 0.378 0.0426 3.54 0.367 0.028 2.48 4.2601 0.985 1940250 CBMicro_029299 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I22 compound treatment 0.327 -0.00835 -0.69 0.33 -0.00897 -0.79 -1.0524 -0.9977 1940251 CBMicro_029300 COCCCNC(=O)c1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I23 positive control 0.086 -0.249 -20.7 0.086 -0.253 -22.42 -30.4901 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 I24 positive control 0.091 -0.244 -20.29 0.095 -0.244 -21.62 -29.6326 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J01 mock treatment 0.31 -0.0254 -2.1 0.311 -0.028 -2.48 -3.2409 -0.9967 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J02 mock treatment 0.34 0.00465 0.39 0.346 0.00703 0.62 0.7134 0.9734 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J03 compound treatment 0.319 -0.0164 -1.36 0.323 -0.016 -1.41 -1.9606 -0.9998 1481819 CBMicro_029301 CCOc1ccc(cc1)N(CC(=O)Nc2ccccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J04 compound treatment 0.347 0.0116 0.97 0.341 0.00203 0.18 0.811 0.8247 1479635 CBMicro_029302 COc1cccc(OC)c1C(=O)Nc2cccc(c2)C(=O)Nc3ccccc3C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J05 compound treatment 0.355 0.0196 1.63 0.359 0.02 1.78 2.4086 0.9991 1257464 CBMicro_029303 Cn1c(=O)c(N)c2-c3ccccc3C(=O)c4cccc1c42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J06 compound treatment 0.386 0.0506 4.2 0.382 0.043 3.81 5.6697 0.9988 1940252 CBMicro_029304 COc1cc(/C=N/N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J07 compound treatment 0.336 6.45E-4 0.05 0.313 -0.026 -2.3 -1.5893 -0.6905 1711609 CBMicro_029305 CN(C)C(=O)c1ccc(CN2CCc3ccccc3C2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J08 compound treatment 0.289 -0.0464 -3.85 0.31 -0.029 -2.57 -4.5364 -0.9806 1206869 CBMicro_029306 OC(CNCC1(CCCC1)c2ccc3OCCOc3c2)COc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J09 compound treatment 0.328 -0.00735 -0.61 0.346 0.00703 0.62 0.009 0.0103 1940253 CBMicro_029307 CC(C)CNC(=O)C(=O)Nc1ccc(Oc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J10 compound treatment 0.326 -0.00935 -0.78 0.333 -0.00597 -0.53 -0.9231 -0.9824 1940254 CBMicro_029308 C(Cc1nc2ccccc2s1)SCCc3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J11 compound treatment 0.343 0.00765 0.63 0.344 0.00503 0.45 0.7642 0.9851 1940255 CBMicro_029309 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)CN4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J12 compound treatment 0.334 -0.00135 -0.11 0.334 -0.00497 -0.44 -0.3908 -0.8602 1031427 CBMicro_029310 CC(=O)OC(OC(=O)C)c1ccc(cc1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J13 compound treatment 0.385 0.0496 4.12 0.397 0.058 5.14 6.551 0.994 1282276 CBMicro_029311 CC(C)N(C(C)C)C(=O)c1ccc(CN(c2cc(Cl)ccc2C)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J14 compound treatment 0.341 0.00565 0.47 0.35 0.011 0.98 1.0228 0.9433 1226546 CBMicro_029312 CC(C)OC(=O)c1sc(NC(=O)c2cccc(Cl)c2)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J15 compound treatment 0.351 0.0156 1.3 0.351 0.012 1.07 1.6725 0.9952 1129499 CBMicro_029313 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J16 compound treatment 0.333 -0.00235 -0.2 0.343 0.00403 0.36 0.1145 0.2811 1706111 CBMicro_029314 CCOC(=O)c1nc[nH]c1C(=O)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J17 compound treatment 0.351 0.0156 1.3 0.347 0.00803 0.71 1.4218 0.9599 1940256 CBMicro_029315 O=C(Cn1nnc2ccccc12)NNC(=S)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J18 compound treatment 0.351 0.0156 1.3 0.351 0.012 1.07 1.6725 0.9952 1372809 CBMicro_029316 C(Nn1c(CN2CCOCC2)nc3ccccc13)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J19 compound treatment 0.333 -0.00235 -0.2 0.338 -9.67E-4 -0.09 -0.1988 -0.9315 1634882 CBMicro_029317 COc1ccc(NC(=O)C(C)Sc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J20 compound treatment 0.346 0.0106 0.88 0.345 0.00603 0.53 1.003 0.971 1515241 CBMicro_029318 OC(=O)c1ccccc1NS(=O)(=O)c2cccc3cccnc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J21 compound treatment 0.342 0.00665 0.55 0.339 3.33E-5 0.0 0.3922 0.7109 1634475 CBMicro_029319 Clc1ccccc1C(=O)Nc2ccc3C(=O)N(C(=O)c3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J22 compound treatment 0.335 -3.55E-4 -0.03 0.338 -9.67E-4 -0.09 -0.0814 -0.8986 1660165 CBMicro_029320 CNC1(Oc2ccccc2C(=C1C)C#Cc3ccccc3)c4ccc(OC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J23 positive control 0.086 -0.249 -20.7 0.087 -0.252 -22.33 -30.4275 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 J24 positive control 0.092 -0.243 -20.2 0.098 -0.241 -21.35 -29.3859 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K01 mock treatment 0.34 0.00465 0.39 0.339 3.33E-5 0.0 0.2748 0.7125 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K02 mock treatment 0.334 -0.00135 -0.11 0.34 0.00103 0.09 -0.0148 -0.1019 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K03 compound treatment 0.322 -0.0134 -1.11 0.336 -0.00297 -0.26 -0.9699 -0.8512 1646033 CBMicro_029321 Cc1ccc(cc1)N(CC(=O)Nc2cccc3ccccc23)S(=O)(=O)c4ccc(F)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K04 compound treatment 0.33 -0.00535 -0.44 0.339 3.33E-5 0.0 -0.3123 -0.7024 1940257 CBMicro_029322 O=C/1C2CC(C\C1=C\c3ccco3)C(=O)/C(=C\c4ccco4)/C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K05 compound treatment 0.349 0.0136 1.13 0.375 0.036 3.19 3.059 0.9028 1940258 CBMicro_029323 CC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K06 compound treatment 0.32 -0.0154 -1.27 0.319 -0.02 -1.77 -2.1526 -0.987 1940259 CBMicro_029324 Cc1cc(C)c(OCCNC(C)(C)C)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K07 compound treatment 0.327 -0.00835 -0.69 0.332 -0.00697 -0.62 -0.927 -0.9983 1735546 CBMicro_029325 COc1ccccc1CC(=O)Nc2ccc(Br)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K08 compound treatment 0.326 -0.00935 -0.78 0.33 -0.00897 -0.79 -1.1111 -0.9999 1739612 CBMicro_029326 COc1cc(NC(=O)COc2ccc(Cl)cc2Cl)c3ncccc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K09 compound treatment 0.326 -0.00935 -0.78 0.331 -0.00797 -0.71 -1.0484 -0.9989 1141988 CBMicro_029327 CCN(CC)c1ccc(cc1)C(=O)NCc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K10 compound treatment 0.389 0.0536 4.45 0.387 0.048 4.26 6.1592 0.9997 1940260 CBMicro_029328 [O-][N+](=O)c1ccc(COc2ccccc2/C=N/Nc3nc4ccccc4s3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K11 compound treatment 0.35 0.0146 1.22 0.356 0.017 1.51 1.9271 0.9942 1514323 CBMicro_029329 CCN(CC)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K12 compound treatment 0.26 -0.0754 -6.26 0.28 -0.059 -5.23 -8.1187 -0.996 1940261 CBMicro_029330 CCN1C(=O)/C(=C/c2ccc(o2)c3ccccc3[N+](=O)[O-])/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K13 compound treatment 0.355 0.0196 1.63 0.371 0.032 2.84 3.1606 0.9654 1940262 CBMicro_029331 Cc1cc(C)nc(N/C(=N/C(=O)c2ccccc2)/Nc3ccccc3)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K14 compound treatment 0.316 -0.0194 -1.61 0.319 -0.02 -1.77 -2.3874 -0.9988 1940263 CBMicro_029332 COc1ccccc1CC(=O)n2nnc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K15 compound treatment 0.361 0.0256 2.13 0.373 0.034 3.02 3.6382 0.9855 1739506 CBMicro_029333 COc1ccc(cc1NC(=O)c2cccc(F)c2)C(=O)Nc3cc(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K16 compound treatment 0.383 0.0476 3.96 0.391 0.052 4.61 6.0576 0.9971 1940264 CBMicro_029334 COc1ccc(cc1)C2CC(=NN2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K17 compound treatment 0.339 0.00365 0.3 0.343 0.00403 0.36 0.4667 0.9966 1546706 CBMicro_029335 COc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)c3ccccc3C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K18 compound treatment 0.331 -0.00435 -0.36 0.331 -0.00797 -0.71 -0.7549 -0.9517 1586045 CBMicro_029336 COc1ccc(CNC(=O)c2c(Cl)cccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K19 compound treatment 0.372 0.0366 3.04 0.364 0.025 2.22 3.7199 0.988 1489394 CBMicro_029337 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccc(C)cc4-c5c(ssc5=S)C3(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K20 compound treatment 0.324 -0.0114 -0.94 0.327 -0.012 -1.06 -1.4165 -0.9983 1477254 CBMicro_029338 CN(C)c1cccc(c1)C(=O)Nc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K21 compound treatment 0.335 -3.55E-4 -0.03 0.336 -0.00297 -0.26 -0.2067 -0.7814 1940265 CBMicro_029339 COc1ccc(Cl)cc1N(CC(=O)N2CCCCC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K22 compound treatment 0.342 0.00665 0.55 0.34 0.00103 0.09 0.4548 0.8134 1558720 CBMicro_029340 Cc1ccc(cc1)N(CC(=O)N2CCCC2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K23 positive control 0.085 -0.25 -20.78 0.088 -0.251 -22.24 -30.4235 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 K24 positive control 0.098 -0.237 -19.7 0.094 -0.245 -21.71 -29.2844 -0.9988 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L01 mock treatment 0.338 0.00265 0.22 0.342 0.00303 0.27 0.3454 0.995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L02 mock treatment 0.335 -3.55E-4 -0.03 0.342 0.00303 0.27 0.1693 0.6259 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L03 compound treatment 0.324 -0.0114 -0.94 0.333 -0.00597 -0.53 -1.0405 -0.9626 1362371 CBMicro_029341 COc1ccc(cc1O)C2Nc3cccc4cccc(N2)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L04 compound treatment 0.334 -0.00135 -0.11 0.342 0.00303 0.27 0.1106 0.3794 1228980 CBMicro_029342 COc1ccccc1CNC(=O)CC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L05 compound treatment 0.335 -3.55E-4 -0.03 0.339 3.33E-5 0.0 -0.0187 -0.633 1723486 CBMicro_029343 COc1ccc(CCNC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L06 compound treatment 0.343 0.00765 0.63 0.347 0.00803 0.71 0.9522 0.9984 1940266 CBMicro_029344 COc1ccc(OC)c(/C=C/2\C(=NN(C2=O)c3ccc(C)cc3)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L07 compound treatment 0.321 -0.0144 -1.19 0.324 -0.015 -1.33 -1.7806 -0.9986 1278804 CBMicro_029345 O=C(Nc1cccc2ccccc12)c3ccc(CN4CCc5ccccc5C4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L08 compound treatment 0.341 0.00565 0.47 0.342 0.00303 0.27 0.5215 0.9652 1940267 CBMicro_029346 Brc1ccc(OCC(=O)Nc2ccc(cc2)N3CCOCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L09 compound treatment 0.338 0.00265 0.22 0.346 0.00703 0.62 0.596 0.9019 1940268 CBMicro_029347 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(C)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L10 compound treatment 0.326 -0.00935 -0.78 0.327 -0.012 -1.06 -1.2991 -0.9883 1940269 CBMicro_029348 CC(=O)c1ccc(NS(=O)(=O)c2ccccc2[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L11 compound treatment 0.322 -0.0134 -1.11 0.327 -0.012 -1.06 -1.5339 -0.9998 1534647 CBMicro_029349 CN1CCN(CC1)C(=O)c2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L12 compound treatment 0.312 -0.0234 -1.94 0.319 -0.02 -1.77 -2.6222 -0.999 1017279 CBMicro_029350 Cc1ccc(cc1)S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L13 compound treatment 0.332 -0.00335 -0.28 0.333 -0.00597 -0.53 -0.5708 -0.9552 1940270 CBMicro_029351 COC(=O)c1ccc(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L14 compound treatment 0.343 0.00765 0.63 0.344 0.00503 0.45 0.7642 0.9851 1151659 CBMicro_029352 Clc1ccc(cc1)c2cc(C(=O)NCCN3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L15 compound treatment 0.328 -0.00735 -0.61 0.331 -0.00797 -0.71 -0.931 -0.9974 1740124 CBMicro_029353 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L16 compound treatment 0.361 0.0256 2.13 0.367 0.028 2.48 3.2622 0.997 1940271 CBMicro_029354 COc1ccc(/C=C/C(=O)Nc2nc(cs2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L17 compound treatment 0.308 -0.0274 -2.27 0.309 -0.03 -2.66 -3.4837 -0.997 1940272 CBMicro_029355 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NCCSCc2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L18 compound treatment 0.333 -0.00235 -0.2 0.339 3.33E-5 0.0 -0.1361 -0.6963 1940273 CBMicro_029356 C/C(=N\NC(=O)CN(Cc1ccco1)S(=O)(=O)c2ccccc2)/CCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L19 compound treatment 0.336 6.45E-4 0.05 0.338 -9.67E-4 -0.09 -0.0227 -0.2247 1940274 CBMicro_029357 CCNC(=S)NNc1nc(nc(n1)N2CCOCC2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L20 compound treatment 0.336 6.45E-4 0.05 0.339 3.33E-5 0.0 0.04 0.745 1486013 CBMicro_029358 Cc1ccc(cc1)N2C(=O)C(O)C(O)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L21 compound treatment 0.35 0.0146 1.22 0.348 0.00903 0.8 1.4258 0.9794 1476747 CBMicro_029359 CCOc1ccc(cc1OCC)C(=O)Nc2ccc(OC)cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L22 compound treatment 0.333 -0.00235 -0.2 0.339 3.33E-5 0.0 -0.1361 -0.6963 1564084 CBMicro_029360 COc1ccc(Cl)cc1C(=O)Nc2nc(cs2)c3ccc(C)cc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L23 positive control 0.085 -0.25 -20.78 0.086 -0.253 -22.42 -30.5488 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 L24 positive control 0.092 -0.243 -20.2 0.095 -0.244 -21.62 -29.5739 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M01 mock treatment 0.336 6.45E-4 0.05 0.34 0.00103 0.09 0.1026 0.9674 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M02 mock treatment 0.333 -0.00235 -0.2 0.339 3.33E-5 0.0 -0.1361 -0.6963 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M03 compound treatment 0.325 -0.0104 -0.86 0.329 -0.00997 -0.88 -1.2324 -0.9999 1417353 CBMicro_029361 CCOc1ccccc1OCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M04 compound treatment 0.328 -0.00735 -0.61 0.33 -0.00897 -0.79 -0.9937 -0.9915 1129985 CBMicro_029362 Cc1cccc2c(=O)oc(nc12)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M05 compound treatment 0.305 -0.0304 -2.52 0.305 -0.034 -3.01 -3.9105 -0.9961 1781374 CBMicro_029363 CCC(=O)N1N=C2C(C1c3cccc(c3)[N+](=O)[O-])N4CCC2CC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M06 compound treatment 0.335 -3.55E-4 -0.03 0.34 0.00103 0.09 0.0439 0.4566 1493337 CBMicro_029364 Cc1cc(C)c(C(=O)c2ccc(cc2)C(=O)Nc3cc(C)c(O)c(C)c3)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M07 compound treatment 0.315 -0.0204 -1.69 0.319 -0.02 -1.77 -2.4461 -0.9997 1940275 CBMicro_029365 COc1ccccc1CC(=O)Nc2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M08 compound treatment 0.325 -0.0104 -0.86 0.331 -0.00797 -0.71 -1.1071 -0.9952 1940276 CBMicro_029366 COc1ccccc1CC(=O)Nc2cc(ccc2OC)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M09 compound treatment 0.341 0.00565 0.47 0.342 0.00303 0.27 0.5215 0.9652 1602682 CBMicro_029367 CCOc1ccc(cc1OCC)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M10 compound treatment 0.335 -3.55E-4 -0.03 0.339 3.33E-5 0.0 -0.0187 -0.633 1786040 CBMicro_029368 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(O)C[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M11 compound treatment 0.34 0.00465 0.39 0.345 0.00603 0.53 0.6508 0.9871 1458370 CBMicro_029369 CCN(CC)c1ccc(cc1)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M12 compound treatment 0.354 0.0186 1.55 0.355 0.016 1.42 2.0993 0.9991 1462540 CBMicro_029370 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)NC3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M13 compound treatment 0.356 0.0206 1.71 0.371 0.032 2.84 3.2193 0.9708 1940277 CBMicro_029371 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(cc(c2)[N+](=O)[O-])C(=O)OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M14 compound treatment 0.332 -0.00335 -0.28 0.334 -0.00497 -0.44 -0.5082 -0.9756 1367161 CBMicro_029372 CCN(CC)c1ccc(cc1)C(=O)NCC(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M15 compound treatment 0.376 0.0406 3.37 0.374 0.035 3.1 4.5814 0.9991 1940278 CBMicro_029373 COc1cc(/C=C/2\S/C(=N\Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc(Br)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M16 compound treatment 0.324 -0.0114 -0.94 0.33 -0.00897 -0.79 -1.2285 -0.9964 1715776 CBMicro_029374 Clc1cccc(c1)N2CCN(CC2)C(=O)CC(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M17 compound treatment 0.329 -0.00635 -0.53 0.328 -0.011 -0.97 -1.0603 -0.9588 1940279 CBMicro_029375 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(C)cc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M18 compound treatment 0.332 -0.00335 -0.28 0.335 -0.00397 -0.35 -0.4455 -0.9934 1395414 CBMicro_029376 CCN(CC)c1ccc(cc1)C(=O)Nc2ccc(F)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M19 compound treatment 0.312 -0.0234 -1.94 0.313 -0.026 -2.3 -2.9982 -0.9964 1940280 CBMicro_029377 CC(C)c1ccccc1OCCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M20 compound treatment 0.331 -0.00435 -0.36 0.331 -0.00797 -0.71 -0.7549 -0.9517 1622480 CBMicro_029378 CC(=O)Nc1ccc(cc1)C(=O)Nc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M21 compound treatment 0.33 -0.00535 -0.44 0.331 -0.00797 -0.71 -0.8136 -0.9751 1940281 CBMicro_029379 COc1cc(Br)c(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M22 compound treatment 0.342 0.00665 0.55 0.345 0.00603 0.53 0.7682 0.9999 1940282 CBMicro_029380 Cc1ccc(s1)c2ccc(s2)c3nnc(N)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M23 positive control 0.088 -0.247 -20.54 0.088 -0.251 -22.24 -30.2474 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 M24 positive control 0.099 -0.236 -19.62 0.094 -0.245 -21.71 -29.2257 -0.9987 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N01 mock treatment 0.339 0.00365 0.3 0.341 0.00203 0.18 0.3414 0.9693 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N02 mock treatment 0.343 0.00765 0.63 0.348 0.00903 0.8 1.0149 0.9934 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N03 compound treatment 0.467 0.132 10.93 0.459 0.12 10.64 15.2499 0.9999 1940283 CBMicro_029381 Cc1ccc(o1)C(=O)NCCNc2ccc(cc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N04 compound treatment 0.338 0.00265 0.22 0.348 0.00903 0.8 0.7214 0.869 1940284 CBMicro_029382 FC(F)(F)c1cccc(c1)c2ccc(/C=N/NC(=O)c3ccco3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N05 compound treatment 0.317 -0.0184 -1.52 0.326 -0.013 -1.15 -1.89 -0.9903 1124739 CBMicro_029383 Cc1ccc(o1)C(=O)Nc2cccc(Oc3ccccc3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N06 compound treatment 0.37 0.0346 2.88 0.371 0.032 2.84 4.0412 1.0 1199358 CBMicro_029384 Cc1ccccc1CNC(=O)c2ccc(cc2)N(Cc3ccccc3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N07 compound treatment 0.329 -0.00635 -0.53 0.332 -0.00697 -0.62 -0.8096 -0.9969 1355356 CBMicro_029385 COc1ccccc1NC(=O)c2ccc(CN3CCOCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N08 compound treatment 0.352 0.0166 1.38 0.351 0.012 1.07 1.7312 0.9918 1649110 CBMicro_029386 CCCc1ccc(OCC(=O)Nc2ccc(cc2)N3CCOCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N09 compound treatment 0.342 0.00665 0.55 0.344 0.00503 0.45 0.7055 0.9944 1940285 CBMicro_029387 CC(C)NNC(=O)c1nc(cc(n1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N10 compound treatment 0.385 0.0496 4.12 0.385 0.046 4.08 5.799 1.0 1374796 CBMicro_029388 COc1ccc(cc1)n2cnc3ccc(C)c4nc(C)cc2c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N11 compound treatment 0.369 0.0336 2.79 0.367 0.028 2.48 3.7318 0.9983 1940286 CBMicro_029389 COc1cc(/C=N/NC(=O)C(C)Nc2ccc(Cl)cc2)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N12 compound treatment 0.363 0.0276 2.3 0.373 0.034 3.02 3.7556 0.9909 1940287 CBMicro_029390 Brc1ccc(/C=C/2\SC(=N)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N13 compound treatment 0.353 0.0176 1.46 0.367 0.028 2.48 2.7925 0.9683 1940288 CBMicro_029391 COc1cc(/C=C/2\C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N14 compound treatment 0.329 -0.00635 -0.53 0.332 -0.00697 -0.62 -0.8096 -0.9969 1503267 CBMicro_029392 CC(C)(CN1CCCCC1)NS(=O)(=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N15 compound treatment 0.34 0.00465 0.39 0.341 0.00203 0.18 0.4001 0.94 1588078 CBMicro_029393 Cc1ccc(Cl)cc1N(Cc2ccc(cc2)C(=O)O)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N16 compound treatment 0.342 0.00665 0.55 0.351 0.012 1.07 1.1442 0.9529 1940289 CBMicro_029394 CN(C)c1ccc(/C=C/C(=O)c2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N17 compound treatment 0.345 0.00965 0.8 0.341 0.00203 0.18 0.6936 0.8451 1273689 CBMicro_029395 O=C(N1CCN(CC1)c2ccccc2)c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N18 compound treatment 0.357 0.0216 1.8 0.358 0.019 1.69 2.4634 0.9995 1415935 CBMicro_029396 OC(=O)CNS(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)NCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N19 compound treatment 0.324 -0.0114 -0.94 0.331 -0.00797 -0.71 -1.1658 -0.9899 1690449 CBMicro_029397 Cc1cc(OCCN2CCCC2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N20 compound treatment 0.443 0.108 8.94 0.444 0.105 9.31 12.901 0.9998 1738593 CBMicro_029398 COc1nccnc1NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(F)c(F)c3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N21 compound treatment 0.339 0.00365 0.3 0.352 0.013 1.16 1.0307 0.8632 1258307 CBMicro_029399 CCN(CC)c1ccc(cc1)C(=O)Nc2cccc(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N22 compound treatment 0.337 0.00165 0.14 0.341 0.00203 0.18 0.224 0.9907 1940290 CBMicro_029400 CCc1nnc(NC(=O)c2cnccn2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N23 positive control 0.089 -0.246 -20.45 0.089 -0.25 -22.15 -30.126 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 N24 positive control 0.094 -0.241 -20.04 0.093 -0.246 -21.8 -29.5818 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O01 mock treatment 0.342 0.00665 0.55 0.343 0.00403 0.36 0.6428 0.9779 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O02 mock treatment 0.339 0.00365 0.3 0.343 0.00403 0.36 0.4667 0.9966 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O03 compound treatment 0.331 -0.00435 -0.36 0.331 -0.00797 -0.71 -0.7549 -0.9517 1166656 CBMicro_029401 Nc1ccccc1C(=O)Nc2ccc(cc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O04 compound treatment 0.333 -0.00235 -0.2 0.336 -0.00297 -0.26 -0.3241 -0.9894 1311985 CBMicro_029402 CCOC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O05 compound treatment 0.349 0.0136 1.13 0.348 0.00903 0.8 1.3671 0.9856 1402429 CBMicro_029403 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)N3CCN(CC3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O06 compound treatment 0.343 0.00765 0.63 0.343 0.00403 0.36 0.7015 0.9631 1940291 CBMicro_029404 Cc1cccc2c(Nc3ccc(cc3)S(=O)(=O)N)c4ccc(cc4nc12)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O07 compound treatment 0.32 -0.0154 -1.27 0.325 -0.014 -1.24 -1.7766 -0.9999 1940292 CBMicro_029405 COc1cc(/C=C/2\SC(=S)N(C3CCCCC3)C2=O)ccc1OC(=O)c4cccc(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O08 compound treatment 0.338 0.00265 0.22 0.342 0.00303 0.27 0.3454 0.995 1476979 CBMicro_029406 COc1ccc(CC(=O)Nc2ccccc2F)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O09 compound treatment 0.41 0.0746 6.2 0.413 0.074 6.56 9.0212 0.9996 1940293 CBMicro_029407 COc1cc(/C=C/2\S\C(=N\c3ccccc3)\NC2=O)ccc1OCC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O10 compound treatment 0.326 -0.00935 -0.78 0.331 -0.00797 -0.71 -1.0484 -0.9989 1940294 CBMicro_029408 COCCNC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O11 compound treatment 0.35 0.0146 1.22 0.347 0.00803 0.71 1.3631 0.9675 1669272 CBMicro_029409 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)N3CCc4ccccc4C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O12 compound treatment 0.335 -3.55E-4 -0.03 0.338 -9.67E-4 -0.09 -0.0814 -0.8986 1738893 CBMicro_029410 O=C(NCC1CCCO1)c2ccc3C(=O)N(N4C(=O)c5ccccc5C4=O)C(=O)c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O13 compound treatment 0.343 0.00765 0.63 0.344 0.00503 0.45 0.7642 0.9851 1308929 CBMicro_029411 Cc1ccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(F)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O14 compound treatment 0.34 0.00465 0.39 0.342 0.00303 0.27 0.4628 0.9844 1940295 CBMicro_029412 Brc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O15 compound treatment 0.361 0.0256 2.13 0.358 0.019 1.69 2.6982 0.9934 1940296 CBMicro_029413 COc1ccc(cc1NC(=O)Cc2ccc(OC)c(OC)c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O16 compound treatment 0.342 0.00665 0.55 0.343 0.00403 0.36 0.6428 0.9779 1940297 CBMicro_029414 CCOc1ccc(cc1)N(CC(=O)Nc2ccccc2C(F)(F)F)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O17 compound treatment 0.342 0.00665 0.55 0.339 3.33E-5 0.0 0.3922 0.7109 1940298 CBMicro_029415 Clc1cccc(OCCCN2CCOCC2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O18 compound treatment 0.336 6.45E-4 0.05 0.339 3.33E-5 0.0 0.04 0.745 1940299 CBMicro_029416 CCOc1ccc(cc1)N(CC(=O)N[C@@H]2CCCC[C@H]2O)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O19 compound treatment 0.328 -0.00735 -0.61 0.328 -0.011 -0.97 -1.119 -0.9749 1575667 CBMicro_029417 COc1ccc(CC(=O)N2CCOCC2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O20 compound treatment 0.349 0.0136 1.13 0.349 0.01 0.89 1.4298 0.9928 1303899 CBMicro_029418 CC(=O)Nc1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O21 compound treatment 0.355 0.0196 1.63 0.354 0.015 1.33 2.0953 0.995 1940300 CBMicro_029419 CC(Sc1ccc(Cl)cc1)C(=O)Nc2ccc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O22 compound treatment 0.32 -0.0154 -1.27 0.328 -0.011 -0.97 -1.5886 -0.991 1940301 CBMicro_029420 Cc1ccc(OCCCN2CCCC2)c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O23 positive control 0.087 -0.248 -20.62 0.089 -0.25 -22.15 -30.2434 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 O24 positive control 0.091 -0.244 -20.29 0.093 -0.246 -21.8 -29.758 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P01 mock treatment 0.336 6.45E-4 0.05 0.34 0.00103 0.09 0.1026 0.9674 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P02 mock treatment 0.338 0.00265 0.22 0.343 0.00403 0.36 0.408 0.9726 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P03 compound treatment 0.336 6.45E-4 0.05 0.34 0.00103 0.09 0.1026 0.9674 1619167 CBMicro_029421 CC(C)CNC(=O)C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P04 compound treatment 0.345 0.00965 0.8 0.347 0.00803 0.71 1.0696 0.9983 1940302 CBMicro_029422 COc1ccc(Cl)cc1N(CC(=O)N2CCOCC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P05 compound treatment 0.341 0.00565 0.47 0.345 0.00603 0.53 0.7095 0.9978 1322860 CBMicro_029423 COc1ccc(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P06 compound treatment 0.378 0.0426 3.54 0.383 0.044 3.9 5.2628 0.9988 1183587 CBMicro_029424 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2ccc3OCOc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P07 compound treatment 0.344 0.00865 0.72 0.35 0.011 0.98 1.1989 0.9884 1940303 CBMicro_029425 CCC(Nc1ccc(Br)cc1)C(=O)N/N=C/c2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P08 compound treatment 0.337 0.00165 0.14 0.332 -0.00697 -0.62 -0.34 -0.5377 1342057 CBMicro_029426 O=C(Nc1ccc(cc1)N2CCOCC2)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P09 compound treatment 0.332 -0.00335 -0.28 0.333 -0.00597 -0.53 -0.5708 -0.9552 1940304 CBMicro_029427 [O-][N+](=O)c1ccc(cc1)c2nnc(o2)c3ccccc3I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P10 compound treatment 0.343 0.00765 0.63 0.375 0.036 3.19 2.7068 0.8314 1327668 CBMicro_029428 CC1CC(N(C(=O)c2cccs2)c3ccccc3)c4ccccc4N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P11 compound treatment 0.342 0.00665 0.55 0.337 -0.00197 -0.17 0.2669 0.4612 1537012 CBMicro_029429 Ic1ccc2nc(CN3C(=O)c4ccccc4C3=O)oc(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P12 compound treatment 0.323 -0.0124 -1.03 0.327 -0.012 -1.06 -1.4752 -0.9999 1431164 CBMicro_029430 O=C(Nc1ccccc1C(=O)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P13 compound treatment 0.334 -0.00135 -0.11 0.338 -9.67E-4 -0.09 -0.1401 -0.991 1271564 CBMicro_029431 COc1cc(NS(=O)(=O)c2ccc(F)cc2)c(OC)cc1NC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P14 compound treatment 0.351 0.0156 1.3 0.359 0.02 1.78 2.1738 0.9882 1701201 CBMicro_029432 Cc1ccc(NCC(O)Cn2c3ccccc3c4ccccc24)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P15 compound treatment 0.529 0.194 16.08 0.499 0.16 14.18 21.3961 0.998 1940305 CBMicro_029433 OC(=O)CN1C(=O)/C(=C\c2ccc(o2)c3cccc4C(=O)c5ccccc5C(=O)c34)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P16 compound treatment 0.33 -0.00535 -0.44 0.331 -0.00797 -0.71 -0.8136 -0.9751 1684400 CBMicro_029434 COc1ccc(cc1)C(=O)n2nc(C)c(Sc3ccccc3)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P17 compound treatment 0.322 -0.0134 -1.11 0.326 -0.013 -1.15 -1.5965 -0.9998 1940306 CBMicro_029435 Cc1ccc(Cl)c(OCCCCNC(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P18 compound treatment 0.376 0.0406 3.37 0.377 0.038 3.37 4.7694 1.0 1550831 CBMicro_029436 NC(=O)c1c(NC(=O)c2ccccc2F)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P19 compound treatment 0.332 -0.00335 -0.28 0.336 -0.00297 -0.26 -0.3828 -0.9996 1940307 CBMicro_029437 O=C(CSc1nc2ccccc2s1)NNC(=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P20 compound treatment 0.358 0.0226 1.88 0.363 0.024 2.13 2.8354 0.9981 1940308 CBMicro_029438 CCOc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P21 compound treatment 0.33 -0.00535 -0.44 0.332 -0.00697 -0.62 -0.7509 -0.987 1940309 CBMicro_029439 [O-][N+](=O)c1cccc(c1)N(CC(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P22 compound treatment 0.339 0.00365 0.3 0.337 -0.00197 -0.17 0.0907 0.2598 1124928 CBMicro_029440 CC(C)NC(=O)c1cc(nc2ccccc12)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P23 positive control 0.089 -0.246 -20.45 0.09 -0.249 -22.06 -30.0634 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.777 P24 positive control 0.092 -0.243 -20.2 0.093 -0.246 -21.8 -29.6993 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A01 mock treatment 0.32 -0.0199 -1.65 0.323 -0.0159 -1.41 -2.163 -0.9969 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A02 mock treatment 0.323 -0.0169 -1.4 0.334 -0.00491 -0.43 -1.2976 -0.885 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A03 compound treatment 0.313 -0.0269 -2.23 0.316 -0.0229 -2.03 -3.0126 -0.9989 1940310 CBMicro_029441 Cc1ccc(cc1)C(=O)Nc2ccccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A04 compound treatment 0.326 -0.0139 -1.15 0.329 -0.00991 -0.88 -1.4348 -0.9911 1484558 CBMicro_029442 CCCc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A05 compound treatment 0.319 -0.0209 -1.73 0.318 -0.0209 -1.85 -2.535 -0.9994 1779918 CBMicro_029443 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A06 compound treatment 0.333 -0.00687 -0.57 0.33 -0.00891 -0.79 -0.9612 -0.9872 1211338 CBMicro_029444 COc1ccc(CC(=O)Nc2cc(C)cc(C)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A07 compound treatment 0.311 -0.0289 -2.4 0.319 -0.0199 -1.76 -2.942 -0.9886 1607633 CBMicro_029445 Oc1ccccc1C(=O)N2CCCc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A08 compound treatment 0.323 -0.0169 -1.4 0.325 -0.0139 -1.23 -1.8616 -0.998 1940311 CBMicro_029446 COc1ccc(/C=C\2/SC(=O)N(CNc3ccc(I)cc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A09 compound treatment 0.313 -0.0269 -2.23 0.316 -0.0229 -2.03 -3.0126 -0.9989 1940312 CBMicro_029447 Clc1cccc(Cl)c1OCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A10 compound treatment 0.303 -0.0369 -3.06 0.302 -0.0369 -3.27 -4.4769 -0.9995 1184500 CBMicro_029448 Oc1cccc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A11 compound treatment 0.322 -0.0179 -1.48 0.324 -0.0149 -1.32 -1.9829 -0.9983 1727470 CBMicro_029449 O=C(NCc1ccco1)C2CC3CCC2C3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A12 compound treatment 0.312 -0.0279 -2.31 0.313 -0.0259 -2.3 -3.2593 -1.0 1940313 CBMicro_029450 O/N=C(\c1cc2/C(=N\O)/CCCCc2s1)/c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A13 compound treatment 0.319 -0.0209 -1.73 0.315 -0.0239 -2.12 -2.723 -0.995 1940314 CBMicro_029451 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A14 compound treatment 0.351 0.0111 0.92 0.348 0.00909 0.81 1.2234 0.9977 1386824 CBMicro_029452 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2ccc(F)c(Cl)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A15 compound treatment 0.319 -0.0209 -1.73 0.314 -0.0249 -2.21 -2.7857 -0.9928 1043938 CBMicro_029453 Oc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A16 compound treatment 0.349 0.00913 0.76 0.361 0.0221 1.96 1.9207 0.9147 1650213 CBMicro_029454 Cc1ccc(cc1)N(CC(=O)NC2CCCC2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A17 compound treatment 0.326 -0.0139 -1.15 0.322 -0.0169 -1.5 -1.8735 -0.9915 1940315 CBMicro_029455 O=C(/C=C/c1ccccc1)n2nnc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A18 compound treatment 0.374 0.0341 2.83 0.381 0.0421 3.73 4.6415 0.9908 1393052 CBMicro_029456 CSC1=C(C#N)C(C=C(N1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A19 compound treatment 0.355 0.0151 1.26 0.345 0.00609 0.54 1.2702 0.9289 1940316 CBMicro_029457 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A20 compound treatment 0.339 -8.67E-4 -0.07 0.337 -0.00191 -0.17 -0.1703 -0.9276 1046948 CBMicro_029458 NNc1nc(nc(n1)N2CCCCC2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A21 compound treatment 0.321 -0.0189 -1.57 0.316 -0.0229 -2.03 -2.543 -0.9918 1940317 CBMicro_029459 CC(=O)N/C(=C/c1ccc(Cl)cc1)/C(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A22 compound treatment 0.328 -0.0119 -0.99 0.323 -0.0159 -1.41 -1.6934 -0.9847 1347336 CBMicro_029460 O=C(CN1C(=O)c2ccccc2C1=O)N3CCN(CC3)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A23 positive control 0.082 -0.258 -21.41 0.083 -0.256 -22.68 -31.174 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 A24 positive control 0.085 -0.255 -21.16 0.086 -0.253 -22.41 -30.8099 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B01 mock treatment 0.333 -0.00687 -0.57 0.33 -0.00891 -0.79 -0.9612 -0.9872 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B02 mock treatment 0.346 0.00613 0.51 0.343 0.00409 0.36 0.6166 0.9862 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B03 compound treatment 0.329 -0.0109 -0.9 0.332 -0.00691 -0.61 -1.0707 -0.9821 1940318 CBMicro_029461 CCOc1ccccc1NC=C2C(=O)N(C)C(=O)N(C)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B04 compound treatment 0.333 -0.00687 -0.57 0.337 -0.00191 -0.17 -0.5226 -0.8789 1473538 CBMicro_029462 Cc1onc(c1C(=O)Nc2cc(C)cc(C)n2)c3c(Cl)cccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B05 compound treatment 0.328 -0.0119 -0.99 0.332 -0.00691 -0.61 -1.1294 -0.9738 1178737 CBMicro_029463 COc1ccc(cc1NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B06 compound treatment 0.332 -0.00787 -0.65 0.323 -0.0159 -1.41 -1.4586 -0.9388 1940319 CBMicro_029464 CCN1C(=C(C(NC1=O)c2ccc(cc2)[N+](=O)[O-])C(=O)OCCOc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B07 compound treatment 0.356 0.0161 1.34 0.355 0.0161 1.43 1.9556 0.9995 1452619 CBMicro_029465 CN(C)c1cccc(c1)C(=O)NC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B08 compound treatment 0.343 0.00313 0.26 0.345 0.00609 0.54 0.5658 0.9439 1940320 CBMicro_029466 COCCNC(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B09 compound treatment 0.331 -0.00887 -0.74 0.329 -0.00991 -0.88 -1.1413 -0.9962 1780844 CBMicro_029467 CC(=O)Oc1ccc2nc(oc(=O)c2c1)c3ccc(C)c(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B10 compound treatment 0.403 0.0631 5.24 0.429 0.0901 7.98 9.3519 0.9792 1940321 CBMicro_029468 COc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccc(O)c(OC)c3)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B11 compound treatment 0.317 -0.0229 -1.9 0.315 -0.0239 -2.12 -2.8404 -0.9985 1376495 CBMicro_029469 O=C(NCc1ccccc1)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B12 compound treatment 0.328 -0.0119 -0.99 0.324 -0.0149 -1.32 -1.6307 -0.9896 1940322 CBMicro_029470 Ic1ccccc1/C=N/N2C(=O)C3C(C4CCC3C=C4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B13 compound treatment 0.322 -0.0179 -1.48 0.322 -0.0169 -1.5 -2.1083 -1.0 1557804 CBMicro_029471 CN(C)c1cccc(c1)C(=O)Nc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B14 compound treatment 0.347 0.00713 0.59 0.351 0.0121 1.07 1.1766 0.9609 1786037 CBMicro_029472 [O-][N+](=O)c1ccc2OC3(CCCCC3C(C#Cc4ccccc4)c2c1)N5CCOCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B15 compound treatment 0.352 0.0121 1.01 0.347 0.00809 0.72 1.2195 0.9862 1940323 CBMicro_029473 CC(C)(C)OC(=O)N/N=C\1/S/C(=C\C(=O)O)/C(=O)N1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B16 compound treatment 0.338 -0.00187 -0.15 0.33 -0.00891 -0.79 -0.6677 -0.8301 1402118 CBMicro_029474 COc1ccc(CNC(=O)c2cccc(c2)N(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B17 compound treatment 0.363 0.0231 1.92 0.372 0.0331 2.93 3.4318 0.9789 1780843 CBMicro_029475 CC(=O)Oc1ccc2nc(oc(=O)c2c1)c3ccc([N+](=O)[O-])c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B18 compound treatment 0.334 -0.00587 -0.49 0.329 -0.00991 -0.88 -0.9652 -0.9614 1363387 CBMicro_029476 Cc1cc(C)c(N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B19 compound treatment 0.334 -0.00587 -0.49 0.332 -0.00691 -0.61 -0.7772 -0.9936 1940324 CBMicro_029477 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B20 compound treatment 0.346 0.00613 0.51 0.334 -0.00491 -0.43 0.0526 0.0786 1295630 CBMicro_029478 COc1ccccc1CC(=O)Nc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B21 compound treatment 0.325 -0.0149 -1.23 0.325 -0.0139 -1.23 -1.7442 -1.0 1363101 CBMicro_029479 COc1ccccc1CC(=O)Nc2cccc(F)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B22 compound treatment 0.328 -0.0119 -0.99 0.329 -0.00991 -0.88 -1.3174 -0.9983 1311126 CBMicro_029480 Cc1cc(C)c(C(=O)c2ccc(cc2)C(=O)N)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B23 positive control 0.081 -0.259 -21.49 0.084 -0.255 -22.59 -31.1701 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 B24 positive control 0.088 -0.252 -20.91 0.085 -0.254 -22.5 -30.6965 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C01 mock treatment 0.34 1.33E-4 0.01 0.336 -0.00291 -0.26 -0.1743 -0.6761 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C02 mock treatment 0.357 0.0171 1.42 0.348 0.00909 0.81 1.5756 0.9638 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C03 compound treatment 0.316 -0.0239 -1.98 0.332 -0.00691 -0.61 -1.8338 -0.8843 1233131 CBMicro_029481 COc1ccc(cc1)N2C(=O)c3ccc(OC)c(OC)c3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C04 compound treatment 0.344 0.00413 0.34 0.349 0.0101 0.89 0.8752 0.9135 1781596 CBMicro_029482 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2cc(C)ccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C05 compound treatment 0.372 0.0321 2.67 0.36 0.0211 1.87 3.2082 0.9849 1779729 CBMicro_029483 [O-][N+](=O)c1ccc2nc(SCC#C)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C06 compound treatment 0.336 -0.00387 -0.32 0.336 -0.00291 -0.26 -0.4091 -0.994 1722308 CBMicro_029484 COc1ccc(NC(=O)CC(c2ccccc2)c3ccccc3)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C07 compound treatment 0.331 -0.00887 -0.74 0.33 -0.00891 -0.79 -1.0786 -0.9994 1517725 CBMicro_029485 COc1ccc(CCNC(=O)C2CC2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C08 compound treatment 0.347 0.00713 0.59 0.345 0.00609 0.54 0.8006 0.9989 1781591 CBMicro_029486 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCN(CC2)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C09 compound treatment 0.347 0.00713 0.59 0.346 0.00709 0.63 0.8633 0.9996 1718396 CBMicro_029487 CN(C)c1cccc(c1)C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C10 compound treatment 0.347 0.00713 0.59 0.341 0.00209 0.19 0.55 0.8862 1215713 CBMicro_029488 CC1CCN(CC1)C(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C11 compound treatment 0.328 -0.0119 -0.99 0.328 -0.0109 -0.97 -1.3801 -1.0 1449242 CBMicro_029489 Clc1ccccc1NC(=O)c2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C12 compound treatment 0.364 0.0241 2.0 0.361 0.0221 1.96 2.8012 0.9999 1940325 CBMicro_029490 CCOC(=O)C(=Cc1ccc(OCc2ccc(cc2)[N+](=O)[O-])c(OC)c1)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C13 compound treatment 0.344 0.00413 0.34 0.34 0.00109 0.1 0.3112 0.8727 1470090 CBMicro_029491 COc1ccc(CC(=O)N2CCN(CC2)c3cccc(Cl)c3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C14 compound treatment 0.332 -0.00787 -0.65 0.327 -0.0119 -1.06 -1.2079 -0.9734 1940326 CBMicro_029492 COc1cccc(/C=C\2/SC(=O)N(CNc3ccc(I)cc3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C15 compound treatment 0.326 -0.0139 -1.15 0.326 -0.0129 -1.14 -1.6228 -1.0 1940327 CBMicro_029493 [O-][N+](=O)c1cccc(c1)C(=O)NC(NC(=S)N2CCOCC2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C16 compound treatment 0.349 0.00913 0.76 0.345 0.00609 0.54 0.918 0.9862 1356811 CBMicro_029494 CCC(C)c1ccc(NC(=O)Cc2ccccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C17 compound treatment 0.33 -0.00987 -0.82 0.33 -0.00891 -0.79 -1.1373 -0.9998 1940328 CBMicro_029495 NS(=O)(=O)c1ccc(NC(=O)c2ccccc2[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C18 compound treatment 0.34 1.33E-4 0.01 0.337 -0.00191 -0.17 -0.1116 -0.6594 1504101 CBMicro_029496 CN(c1ccc(cc1)C(=O)Nc2cccnc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C19 compound treatment 0.334 -0.00587 -0.49 0.332 -0.00691 -0.61 -0.7772 -0.9936 1779917 CBMicro_029497 CC(C)COC(=O)C(C)Nc1n[nH]c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C20 compound treatment 0.377 0.0371 3.08 0.374 0.0351 3.11 4.379 1.0 1940329 CBMicro_029498 COc1ccc(cc1NC(=O)CC(c2ccccc2)c3ccccc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C21 compound treatment 0.34 1.33E-4 0.01 0.335 -0.00391 -0.35 -0.237 -0.6841 1940330 CBMicro_029499 CCOc1cccc2sc(NC(=O)c3cccc(c3)[N+](=O)[O-])nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C22 compound treatment 0.322 -0.0179 -1.48 0.33 -0.00891 -0.79 -1.6069 -0.9564 1940331 CBMicro_029500 Cc1cc(C)c(/C=C\2/SC(=N)NC2=O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C23 positive control 0.084 -0.256 -21.24 0.082 -0.257 -22.77 -31.1193 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 C24 positive control 0.092 -0.248 -20.58 0.088 -0.251 -22.24 -30.2737 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D01 mock treatment 0.34 1.33E-4 0.01 0.34 0.00109 0.1 0.0764 0.7828 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D02 mock treatment 0.345 0.00513 0.43 0.341 0.00209 0.19 0.4325 0.9306 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D03 compound treatment 0.333 -0.00687 -0.57 0.335 -0.00391 -0.35 -0.6479 -0.9714 1940332 CBMicro_029501 CC(=O)C1=C(C)NC(=O)NC1c2ccccc2OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D04 compound treatment 0.342 0.00213 0.18 0.341 0.00209 0.19 0.2564 0.9997 1640150 CBMicro_029502 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D05 compound treatment 0.345 0.00513 0.43 0.335 -0.00391 -0.35 0.0566 0.103 1940333 CBMicro_029503 CCOc1ccc(cc1)N(CC(=O)Nc2cccc(c2)C(=O)C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D06 compound treatment 0.368 0.0281 2.34 0.368 0.0291 2.58 3.4747 0.9988 1324587 CBMicro_029504 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D07 compound treatment 0.336 -0.00387 -0.32 0.338 -9.06E-4 -0.08 -0.2838 -0.8576 1740415 CBMicro_029505 COc1ccc(CC(=O)Nc2cccc(F)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D08 compound treatment 0.365 0.0251 2.09 0.361 0.0221 1.96 2.8599 0.9995 1940334 CBMicro_029506 COc1ccc(/C=C/2\S/C(=N\Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D09 compound treatment 0.354 0.0141 1.17 0.343 0.00409 0.36 1.0862 0.8844 1647654 CBMicro_029507 CC1CC(N(c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3)c4ccccc4N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D10 compound treatment 0.31 -0.0299 -2.48 0.317 -0.0219 -1.94 -3.126 -0.9927 1781894 CBMicro_029508 CC(C)c1ccc(OCC(=O)Nc2ncc(s2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D11 compound treatment 0.434 0.0941 7.81 0.398 0.0591 5.24 9.2291 0.981 1308337 CBMicro_029509 Cc1ccc2-c3c(sn(Cc4ccc(Cl)cc4)c3=S)C(C)(C)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D12 compound treatment 0.331 -0.00887 -0.74 0.327 -0.0119 -1.06 -1.2666 -0.9845 1413381 CBMicro_029510 CC(=O)Nc1cccc(NC(=O)c2cc(Cl)ccc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D13 compound treatment 0.363 0.0231 1.92 0.364 0.0251 2.22 2.9305 0.9973 1940335 CBMicro_029511 COc1cc(/C=N/N2C(=O)C3C4CC(C=C4)C3C2=O)cc(I)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D14 compound treatment 0.339 -8.67E-4 -0.07 0.333 -0.00591 -0.52 -0.421 -0.7968 1730858 CBMicro_029512 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(C(=O)O)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D15 compound treatment 0.327 -0.0129 -1.07 0.321 -0.0179 -1.59 -1.8774 -0.9814 1184366 CBMicro_029513 COc1ccccc1CC(=O)Nc2ccc(F)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D16 compound treatment 0.308 -0.0319 -2.65 0.301 -0.0379 -3.36 -4.2461 -0.993 1699256 CBMicro_029514 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccc(Cl)cc2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D17 compound treatment 0.375 0.0351 2.92 0.375 0.0361 3.2 4.3243 0.9989 1786038 CBMicro_029515 [O-][N+](=O)c1ccc2OC3(CCCCC3=Cc2c1)NCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D18 compound treatment 0.324 -0.0159 -1.32 0.323 -0.0159 -1.41 -1.9282 -0.9994 1476932 CBMicro_029516 Clc1cccc(Cl)c1OCCN2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D19 compound treatment 0.345 0.00513 0.43 0.344 0.00509 0.45 0.6205 0.9996 1940336 CBMicro_029517 COc1ccc(N(CC(=O)N2CCCC2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D20 compound treatment 0.347 0.00713 0.59 0.347 0.00809 0.72 0.9259 0.9955 1940337 CBMicro_029518 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)N[C@@H]2CCCC[C@H]2O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D21 compound treatment 0.356 0.0161 1.34 0.338 -9.06E-4 -0.08 0.8903 0.6635 1240998 CBMicro_029519 Cc1ccc(cc1)N(CC(=O)N2CCCCC2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D22 compound treatment 0.339 -8.67E-4 -0.07 0.335 -0.00391 -0.35 -0.2957 -0.8362 1244655 CBMicro_029520 COc1cccc(OC)c1C(=O)Nc2cccc(Oc3ccc4C(=O)N(C(=O)c4c3)c5ccccc5)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D23 positive control 0.085 -0.255 -21.16 0.083 -0.256 -22.68 -30.9979 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 D24 positive control 0.09 -0.25 -20.74 0.092 -0.247 -21.88 -30.1404 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E01 mock treatment 0.327 -0.0129 -1.07 0.33 -0.00891 -0.79 -1.3134 -0.9889 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E02 mock treatment 0.345 0.00513 0.43 0.342 0.00309 0.27 0.4952 0.9773 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E03 compound treatment 0.343 0.00313 0.26 0.34 0.00109 0.1 0.2525 0.9095 1940338 CBMicro_029521 COc1ccc2[nH]c3ccc(cc3c(=O)c2c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E04 compound treatment 0.312 -0.0279 -2.31 0.303 -0.0359 -3.18 -3.8859 -0.9877 1940339 CBMicro_029522 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCCSc2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E05 compound treatment 0.328 -0.0119 -0.99 0.329 -0.00991 -0.88 -1.3174 -0.9983 1940340 CBMicro_029523 COc1ccc(CCNC(=O)/C=C/c2ccc(Cl)cc2Cl)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E06 compound treatment 0.312 -0.0279 -2.31 0.33 -0.00891 -0.79 -2.194 -0.8976 1940341 CBMicro_029524 CN(C)C1(C)C(=O)c2ccccc2C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E07 compound treatment 0.343 0.00313 0.26 0.344 0.00509 0.45 0.5031 0.9657 1243358 CBMicro_029525 Clc1c(sc2cc(Cl)ccc12)C(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E08 compound treatment 0.349 0.00913 0.76 0.333 -0.00591 -0.52 0.166 0.1802 1313703 CBMicro_029526 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2ccc(CC#N)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E09 compound treatment 0.353 0.0131 1.09 0.353 0.0141 1.25 1.6542 0.9977 1645689 CBMicro_029527 COc1ccccc1CC(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E10 compound treatment 0.334 -0.00587 -0.49 0.333 -0.00591 -0.52 -0.7145 -0.9994 1211835 CBMicro_029528 COc1ccc(CC(=O)Nc2cccc(Br)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E11 compound treatment 0.327 -0.0129 -1.07 0.329 -0.00991 -0.88 -1.3761 -0.9953 1940342 CBMicro_029529 Cc1ccccc1NC(=O)/C=C/c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E12 compound treatment 0.312 -0.0279 -2.31 0.313 -0.0259 -2.3 -3.2593 -1.0 1940343 CBMicro_029530 CCN(CC)CCCOc1ccc(C)cc1C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E13 compound treatment 0.341 0.00113 0.09 0.342 0.00309 0.27 0.2604 0.8983 1940344 CBMicro_029531 [O-][N+](=O)c1ccc(OC/C=C/2\Oc3c(cc(Cl)cc3Cl)C2N4CCOCC4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E14 compound treatment 0.33 -0.00987 -0.82 0.314 -0.0249 -2.21 -2.14 -0.9089 1110035 CBMicro_029532 CN(C)S(=O)(=O)N=C1C=CC(=NS(=O)(=O)N(C)C)C=C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E15 compound treatment 0.334 -0.00587 -0.49 0.358 0.0191 1.69 0.8521 0.4839 1940345 CBMicro_029533 COc1cccc(c1)C(=O)NC(NC(=S)Nc2ccc(C)cc2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E16 compound treatment 0.355 0.0151 1.26 0.349 0.0101 0.89 1.5209 0.9861 1286916 CBMicro_029534 Cc1cc(C)c(N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccccc4C(=O)O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E17 compound treatment 0.339 -8.67E-4 -0.07 0.331 -0.00791 -0.7 -0.5463 -0.7756 1879212 CBMicro_029535 [O-][N+](=O)c1cc(ccc1Cl)C(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E18 compound treatment 0.322 -0.0179 -1.48 0.323 -0.0159 -1.41 -2.0456 -0.9997 1940346 CBMicro_029536 COC(C(=O)N/N=C/c1cc(ccc1Cl)[N+](=O)[O-])c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E19 compound treatment 0.327 -0.0129 -1.07 0.325 -0.0139 -1.23 -1.6268 -0.9975 1612338 CBMicro_029537 Cc1cc(NC(=O)c2cccc(C)c2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E20 compound treatment 0.355 0.0151 1.26 0.366 0.0271 2.4 2.5862 0.9543 1940347 CBMicro_029538 Brc1ccc(cc1)c2ccc(/C=C\C(=O)N3CCOCC3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E21 compound treatment 0.338 -0.00187 -0.15 0.334 -0.00491 -0.43 -0.417 -0.9035 1851849 CBMicro_029539 [O-][N+](=O)c1cccc(c1)C(=O)Nc2nc(cs2)c3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E22 compound treatment 0.359 0.0191 1.59 0.365 0.0261 2.31 2.7584 0.9832 1940348 CBMicro_029540 COc1cc(/C=N/N2C(=O)C3C(C4CCC3C=C4)C2=O)cc(I)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E23 positive control 0.082 -0.258 -21.41 0.083 -0.256 -22.68 -31.174 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 E24 positive control 0.088 -0.252 -20.91 0.09 -0.249 -22.06 -30.3831 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F01 mock treatment 0.333 -0.00687 -0.57 0.334 -0.00491 -0.43 -0.7105 -0.9911 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F02 mock treatment 0.34 1.33E-4 0.01 0.338 -9.06E-4 -0.08 -0.049 -0.6039 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F03 compound treatment 0.336 -0.00387 -0.32 0.335 -0.00391 -0.35 -0.4718 -0.9993 1296201 CBMicro_029541 CCN(CC)C(=O)C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F04 compound treatment 0.332 -0.00787 -0.65 0.323 -0.0159 -1.41 -1.4586 -0.9388 1940349 CBMicro_029542 NC(=O)c1ccccc1NC(=O)c2ccc(Cl)cc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F05 compound treatment 0.351 0.0111 0.92 0.357 0.0181 1.6 1.7874 0.9657 1337116 CBMicro_029543 Cc1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F06 compound treatment 0.34 1.33E-4 0.01 0.341 0.00209 0.19 0.139 0.748 1743375 CBMicro_029544 Cc1cc(NC(=O)c2ccc(I)cc2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F07 compound treatment 0.331 -0.00887 -0.74 0.33 -0.00891 -0.79 -1.0786 -0.9994 1940350 CBMicro_029545 COCCCNC(=O)c1c(Cl)cccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F08 compound treatment 0.33 -0.00987 -0.82 0.331 -0.00791 -0.7 -1.0747 -0.997 1781593 CBMicro_029546 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)NCc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F09 compound treatment 0.335 -0.00487 -0.4 0.332 -0.00691 -0.61 -0.7185 -0.9797 1940351 CBMicro_029547 CC1=NN(C(=O)C1C(C(C#N)C#N)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F10 compound treatment 0.364 0.0241 2.0 0.374 0.0351 3.11 3.6159 0.9774 1375184 CBMicro_029548 Cc1ccc(cc1)C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F11 compound treatment 0.337 -0.00287 -0.24 0.326 -0.0129 -1.14 -0.9771 -0.8363 1940352 CBMicro_029549 OCCNC(=O)C(=O)Nc1ccc(Oc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F12 compound treatment 0.375 0.0351 2.92 0.377 0.0381 3.38 4.4496 0.9973 1940353 CBMicro_029550 Cc1ccc2N(C(=O)CN3C(=O)C4CCCCC4C3=O)C(C)(C)CC(C)(c5ccccc5)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F13 compound treatment 0.333 -0.00687 -0.57 0.332 -0.00691 -0.61 -0.8359 -0.9994 1644856 CBMicro_029551 CC(=O)Nc1ccc(cc1)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F14 compound treatment 0.309 -0.0309 -2.56 0.306 -0.0329 -2.92 -3.874 -0.9979 1940354 CBMicro_029552 CCCCNCCCOc1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F15 compound treatment 0.368 0.0281 2.34 0.355 0.0161 1.43 2.66 0.972 1524794 CBMicro_029553 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)NCc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F16 compound treatment 0.349 0.00913 0.76 0.339 9.38E-5 0.01 0.542 0.7148 1940355 CBMicro_029554 COc1ccc(CC(=O)Nc2cc(ccc2C)[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F17 compound treatment 0.314 -0.0259 -2.15 0.309 -0.0299 -2.65 -3.3925 -0.9946 1940356 CBMicro_029555 CC(C)c1ccccc1OCCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F18 compound treatment 0.357 0.0171 1.42 0.348 0.00909 0.81 1.5756 0.9638 1265154 CBMicro_029556 CC(=O)Nc1ccc(cc1)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F19 compound treatment 0.334 -0.00587 -0.49 0.34 0.00109 0.1 -0.2759 -0.5555 1940357 CBMicro_029557 COC(=O)CN(c1ccc(OC)cc1OC)S(=O)(=O)c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F20 compound treatment 0.339 -8.67E-4 -0.07 0.341 0.00209 0.19 0.0803 0.4036 1940358 CBMicro_029558 Cc1ccc(OCCCN2CCOCC2)c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F21 compound treatment 0.348 0.00813 0.68 0.344 0.00509 0.45 0.7967 0.9808 1338080 CBMicro_029559 COc1ccc(NC(=O)CC(c2ccccc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F22 compound treatment 0.356 0.0161 1.34 0.347 0.00809 0.72 1.4543 0.9572 1940359 CBMicro_029560 CC(=O)c1ccc2NC(C3CC=CC3c2c1)c4cccc(c4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F23 positive control 0.084 -0.256 -21.24 0.086 -0.253 -22.41 -30.8686 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 F24 positive control 0.088 -0.252 -20.91 0.093 -0.246 -21.79 -30.1951 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G01 mock treatment 0.327 -0.0129 -1.07 0.335 -0.00391 -0.35 -1.0001 -0.8907 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G02 mock treatment 0.336 -0.00387 -0.32 0.334 -0.00491 -0.43 -0.5344 -0.9889 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G03 compound treatment 0.335 -0.00487 -0.4 0.332 -0.00691 -0.61 -0.7185 -0.9797 1736761 CBMicro_029561 O=S(=O)(N1CCOCC1)c2ccc-3c(Cc4cc(ccc43)S(=O)(=O)N5CCOCC5)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G04 compound treatment 0.34 1.33E-4 0.01 0.345 0.00609 0.54 0.3897 0.7214 1940360 CBMicro_029562 Cc1ccc(cc1N2C(=O)c3ccc(Oc4ccc(cc4)[N+](=O)[O-])cc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G05 compound treatment 0.325 -0.0149 -1.23 0.323 -0.0159 -1.41 -1.8695 -0.9978 1779730 CBMicro_029563 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G06 compound treatment 0.337 -0.00287 -0.24 0.332 -0.00691 -0.61 -0.6011 -0.9153 1781590 CBMicro_029564 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G07 compound treatment 0.346 0.00613 0.51 0.338 -9.06E-4 -0.08 0.3033 0.5883 1940361 CBMicro_029565 COCCOC(=O)C1=C(C)NC(=O)NC1c2cccc(OCc3ccccc3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G08 compound treatment 0.319 -0.0209 -1.73 0.318 -0.0209 -1.85 -2.535 -0.9994 1250832 CBMicro_029566 COc1ccccc1CC(=O)Nc2cccc(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G09 compound treatment 0.332 -0.00787 -0.65 0.366 0.0271 2.4 1.236 0.4967 1940362 CBMicro_029567 COc1cc(cc(OC)c1OC)C(=O)Nc2c(C)cc(C)c(NC(=O)c3cc(OC)c(OC)c(OC)c3)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G10 compound treatment 0.317 -0.0229 -1.9 0.321 -0.0179 -1.59 -2.4644 -0.996 1940363 CBMicro_029568 NC(=O)c1cc(NS(=O)(=O)c2ccc(F)cc2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G11 compound treatment 0.317 -0.0229 -1.9 0.318 -0.0209 -1.85 -2.6524 -0.9999 1940364 CBMicro_029569 CCOC(=O)C1=C(C)N=C2SCC(=O)N2C1c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G12 compound treatment 0.344 0.00413 0.34 0.349 0.0101 0.89 0.8752 0.9135 1402394 CBMicro_029570 COc1cc2CC(=O)c3cc(OC)c(OC)cc3Cc2cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G13 compound treatment 0.359 0.0191 1.59 0.359 0.0201 1.78 2.3824 0.9984 1940365 CBMicro_029571 CC(=O)/C(=N\Nc1cc(C(=O)N)c(Cl)cc1Cl)/Nc2ccc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G14 compound treatment 0.339 -8.67E-4 -0.07 0.336 -0.00291 -0.26 -0.233 -0.8713 1281318 CBMicro_029572 Cc1cccc(C)c1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G15 compound treatment 0.311 -0.0289 -2.4 0.344 0.00509 0.45 -1.3754 -0.564 1940366 CBMicro_029573 CCOc1ccc(NC(=S)NC(NC(=O)CC(C)C)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G16 compound treatment 0.324 -0.0159 -1.32 0.325 -0.0139 -1.23 -1.8029 -0.9994 1940367 CBMicro_029574 Fc1ccccc1/C=C\2/SC(=O)N(CNc3ccc(I)cc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G17 compound treatment 0.336 -0.00387 -0.32 0.347 0.00809 0.72 0.2802 0.3566 1308020 CBMicro_029575 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G18 compound treatment 0.334 -0.00587 -0.49 0.334 -0.00491 -0.43 -0.6518 -0.9984 1781537 CBMicro_029576 [O-][N+](=O)c1ccccc1S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G19 compound treatment 0.325 -0.0149 -1.23 0.325 -0.0139 -1.23 -1.7442 -1.0 1112629 CBMicro_029577 [O-][N+](=O)c1ccccc1NC(=O)c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G20 compound treatment 0.336 -0.00387 -0.32 0.342 0.00309 0.27 -0.0331 -0.0784 1940368 CBMicro_029578 Cc1cc(Br)ccc1NCN2C(=O)S/C(=C/c3ccc4OCOc4c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G21 compound treatment 0.398 0.0581 4.83 0.388 0.0491 4.35 6.4891 0.9987 1940369 CBMicro_029579 CCOC(=O)c1c(C)c(C)sc1NC(=S)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G22 compound treatment 0.339 -8.67E-4 -0.07 0.332 -0.00691 -0.61 -0.4837 -0.7848 1940370 CBMicro_029580 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2cccc(c2)[N+](=O)[O-])SCC(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G23 positive control 0.085 -0.255 -21.16 0.085 -0.254 -22.5 -30.8726 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 G24 positive control 0.091 -0.249 -20.66 0.093 -0.246 -21.79 -30.019 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H01 mock treatment 0.333 -0.00687 -0.57 0.333 -0.00591 -0.52 -0.7732 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H02 mock treatment 0.345 0.00513 0.43 0.339 9.38E-5 0.01 0.3072 0.7208 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H03 compound treatment 0.333 -0.00687 -0.57 0.342 0.00309 0.27 -0.2092 -0.3308 1198590 CBMicro_029581 COc1ccc(OC)c(NC(=O)c2ccc(CN3CCOCC3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H04 compound treatment 0.354 0.0141 1.17 0.346 0.00709 0.63 1.2742 0.9572 1227395 CBMicro_029582 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)C)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H05 compound treatment 0.338 -0.00187 -0.15 0.335 -0.00391 -0.35 -0.3544 -0.9343 1940371 CBMicro_029583 O=C(NCc1ccccn1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H06 compound treatment 0.337 -0.00287 -0.24 0.335 -0.00391 -0.35 -0.4131 -0.9833 1940372 CBMicro_029584 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccccc3Cl)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H07 compound treatment 0.331 -0.00887 -0.74 0.333 -0.00591 -0.52 -0.8906 -0.986 1940373 CBMicro_029585 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N[C@@H]2CCCC[C@H]2O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H08 compound treatment 0.319 -0.0209 -1.73 0.321 -0.0179 -1.59 -2.347 -0.999 1129147 CBMicro_029586 COc1ccc(OC)c(NC(=O)Cc2ccccc2OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H09 compound treatment 0.32 -0.0199 -1.65 0.331 -0.00791 -0.7 -1.6617 -0.9273 1187711 CBMicro_029587 CCOC(=O)c1ccccc1NC(=O)c2cccc(c2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H10 compound treatment 0.312 -0.0279 -2.31 0.31 -0.0289 -2.56 -3.4473 -0.9987 1230218 CBMicro_029588 Cc1cc(NC(=O)c2ccc(Br)o2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H11 compound treatment 0.324 -0.0159 -1.32 0.328 -0.0109 -0.97 -1.6149 -0.9884 1940374 CBMicro_029589 COC(=O)C1=C(C)N2C(=O)CSC2=NC1c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H12 compound treatment 0.321 -0.0189 -1.57 0.325 -0.0139 -1.23 -1.979 -0.993 1940375 CBMicro_029590 O=C1C2C(C3CCC2C=C3)C(=O)N1/N=C/c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H13 compound treatment 0.335 -0.00487 -0.4 0.347 0.00809 0.72 0.2215 0.2691 1247811 CBMicro_029591 COc1ccc(CC(=O)Nc2ccc(Br)cc2C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H14 compound treatment 0.322 -0.0179 -1.48 0.325 -0.0139 -1.23 -1.9203 -0.9958 1498109 CBMicro_029592 Cc1cc(Br)ccc1N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H15 compound treatment 0.333 -0.00687 -0.57 0.349 0.0101 0.89 0.2294 0.2163 1324371 CBMicro_029593 CN(c1ccc(cc1)C(=O)Nc2c(C)cccc2C)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H16 compound treatment 0.325 -0.0149 -1.23 0.323 -0.0159 -1.41 -1.8695 -0.9978 1741151 CBMicro_029594 CC(=C)C(C)(OC(=O)C)C#CCN1CCOCC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H17 compound treatment 0.333 -0.00687 -0.57 0.335 -0.00391 -0.35 -0.6479 -0.9714 1255574 CBMicro_029595 COc1ccccc1CNC(=O)c2cccc(c2)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H18 compound treatment 0.333 -0.00687 -0.57 0.327 -0.0119 -1.06 -1.1492 -0.9582 1507968 CBMicro_029596 Cc1ccc(cc1NC(=O)C(c2ccccc2)c3ccccc3)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H19 compound treatment 0.335 -0.00487 -0.4 0.335 -0.00391 -0.35 -0.5305 -0.997 1700247 CBMicro_029597 CN(c1ccc(cc1)C(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H20 compound treatment 0.316 -0.0239 -1.98 0.321 -0.0179 -1.59 -2.5231 -0.9939 1605693 CBMicro_029598 Cc1cccc(NC(=O)c2cc(Cl)ccc2Cl)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H21 compound treatment 0.334 -0.00587 -0.49 0.335 -0.00391 -0.35 -0.5892 -0.986 1781602 CBMicro_029599 CCOC(=O)C1CCN(CC1)C(=O)c2cc(cc(c2)[N+](=O)[O-])C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H22 compound treatment 0.333 -0.00687 -0.57 0.335 -0.00391 -0.35 -0.6479 -0.9714 1642009 CBMicro_029600 Clc1cccc(OCCN2CCOCC2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H23 positive control 0.092 -0.248 -20.58 0.086 -0.253 -22.41 -30.399 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 H24 positive control 0.091 -0.249 -20.66 0.093 -0.246 -21.79 -30.019 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I01 mock treatment 0.341 0.00113 0.09 0.344 0.00509 0.45 0.3857 0.8365 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I02 mock treatment 0.347 0.00713 0.59 0.346 0.00709 0.63 0.8633 0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I03 compound treatment 0.317 -0.0229 -1.9 0.313 -0.0259 -2.3 -2.9658 -0.9955 1940376 CBMicro_029601 Cc1csc(NC(=O)c2ccc(cc2Cl)[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I04 compound treatment 0.34 1.33E-4 0.01 0.327 -0.0119 -1.06 -0.7383 -0.6997 1940377 CBMicro_029602 COc1cc(C=C2C(=O)N(C(=S)N(C2=O)c3ccc(C)cc3)c4ccc(C)cc4)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I05 compound treatment 0.362 0.0221 1.84 0.358 0.0191 1.69 2.4958 0.9992 1779210 CBMicro_029603 Cc1ccc(Cc2cnc(NC(=O)c3cccc(c3)[N+](=O)[O-])s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I06 compound treatment 0.351 0.0111 0.92 0.345 0.00609 0.54 1.0354 0.9673 1373173 CBMicro_029604 COc1ccc2N(C(=O)C(C)N3C(=O)c4ccccc4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I07 compound treatment 0.333 -0.00687 -0.57 0.327 -0.0119 -1.06 -1.1492 -0.9582 1940378 CBMicro_029605 Clc1ccccc1N2C(=O)C3C4C=CC(C3C2=O)C54CC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I08 compound treatment 0.337 -0.00287 -0.24 0.33 -0.00891 -0.79 -0.7264 -0.8811 1250730 CBMicro_029606 OC(=O)c1cc(NC(=O)COc2ccccc2)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I09 compound treatment 0.341 0.00113 0.09 0.342 0.00309 0.27 0.2604 0.8983 1683456 CBMicro_029607 COc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCCC2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I10 compound treatment 0.327 -0.0129 -1.07 0.321 -0.0179 -1.59 -1.8774 -0.9814 1356467 CBMicro_029608 CCN(CC)CCOc1c(Cl)cccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I11 compound treatment 0.342 0.00213 0.18 0.327 -0.0119 -1.06 -0.6209 -0.5803 1008120 CBMicro_029609 Clc1ccc(NC(=S)NC(=O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I12 compound treatment 0.321 -0.0189 -1.57 0.337 -0.00191 -0.17 -1.227 -0.7789 1203523 CBMicro_029610 CS(=O)(=O)Nc1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I13 compound treatment 0.327 -0.0129 -1.07 0.336 -0.00291 -0.26 -0.9374 -0.8532 1290954 CBMicro_029611 OC(=O)CC(NC(=O)c1ccc(Cl)cc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I14 compound treatment 0.349 0.00913 0.76 0.351 0.0121 1.07 1.294 0.9856 1173904 CBMicro_029612 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4cc(C)ccc4C(=CC3(C)C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I15 compound treatment 0.323 -0.0169 -1.4 0.324 -0.0149 -1.32 -1.9242 -0.9996 1940379 CBMicro_029613 COc1cccc(/C=N/N=C\2/NC(=O)CS2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I16 compound treatment 0.339 -8.67E-4 -0.07 0.337 -0.00191 -0.17 -0.1703 -0.9276 1940380 CBMicro_029614 COc1cc(/C=N/N2C(=O)c3cccc4cccc(C2=O)c34)cc(I)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I17 compound treatment 0.348 0.00813 0.68 0.358 0.0191 1.69 1.674 0.9188 1940381 CBMicro_029615 COc1ccccc1CC2S/C(=N\N=C\c3cccc(c3)[N+](=O)[O-])/NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I18 compound treatment 0.332 -0.00787 -0.65 0.338 -9.06E-4 -0.08 -0.5186 -0.7881 1361069 CBMicro_029616 COc1ccccc1CC(=O)Nc2cc(C)ccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I19 compound treatment 0.331 -0.00887 -0.74 0.33 -0.00891 -0.79 -1.0786 -0.9994 1171316 CBMicro_029617 Cc1cccc(c1)C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I20 compound treatment 0.344 0.00413 0.34 0.35 0.0111 0.98 0.9378 0.9006 1940382 CBMicro_029618 COCCNC(=O)CN(c1ccc(OC)cc1OC)S(=O)(=O)c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I21 compound treatment 0.342 0.00213 0.18 0.348 0.00909 0.81 0.6951 0.8424 1940383 CBMicro_029619 CCOC(=O)c1c(C)c(C)sc1NC(=O)/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I22 compound treatment 0.341 0.00113 0.09 0.339 9.38E-5 0.01 0.0724 0.7666 1940384 CBMicro_029620 CCOC(=O)CNC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I23 positive control 0.085 -0.255 -21.16 0.086 -0.253 -22.41 -30.8099 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 I24 positive control 0.09 -0.25 -20.74 0.092 -0.247 -21.88 -30.1404 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J01 mock treatment 0.315 -0.0249 -2.06 0.323 -0.0159 -1.41 -2.4565 -0.9827 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J02 mock treatment 0.346 0.00613 0.51 0.348 0.00909 0.81 0.9299 0.9755 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J03 compound treatment 0.307 -0.0329 -2.73 0.302 -0.0369 -3.27 -4.2421 -0.9959 1940385 CBMicro_029621 Nc1ccc(cc1Cl)C(c2ccccc2)c3ccc(N)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J04 compound treatment 0.326 -0.0139 -1.15 0.316 -0.0229 -2.03 -2.2494 -0.9639 1940386 CBMicro_029622 COc1ccc(cc1)S(=O)(=O)Nc2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J05 compound treatment 0.314 -0.0259 -2.15 0.348 0.00909 0.81 -0.9486 -0.4136 1301232 CBMicro_029623 Cc1oc(NC(=O)CCCC(=O)O)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J06 compound treatment 0.349 0.00913 0.76 0.332 -0.00691 -0.61 0.1034 0.1061 1940387 CBMicro_029624 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J07 compound treatment 0.337 -0.00287 -0.24 0.337 -0.00191 -0.17 -0.2877 -0.9859 1413142 CBMicro_029625 Clc1ccc(cc1)C(=O)c2ccccc2C(=O)n3nnc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J08 compound treatment 0.312 -0.0279 -2.31 0.329 -0.00991 -0.88 -2.2566 -0.912 1657551 CBMicro_029626 Cc1cc(OCCN2CCCCC2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J09 compound treatment 0.304 -0.0359 -2.98 0.313 -0.0259 -2.3 -3.7289 -0.9917 1226489 CBMicro_029627 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(C)c(Cl)c2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J10 compound treatment 0.283 -0.0569 -4.72 0.284 -0.0549 -4.87 -6.779 -0.9999 1940388 CBMicro_029628 C/C(=C\c1ccccc1)/C=C/2\SC(=O)N(C2=O)c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J11 compound treatment 0.341 0.00113 0.09 0.343 0.00409 0.36 0.3231 0.862 1940389 CBMicro_029629 CN(C)NC1S/C(=C/C(=O)O)/C(=O)N1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J12 compound treatment 0.319 -0.0209 -1.73 0.318 -0.0209 -1.85 -2.535 -0.9994 1403321 CBMicro_029630 CCN(CC)CCOc1c(C)cc(C)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J13 compound treatment 0.33 -0.00987 -0.82 0.323 -0.0159 -1.41 -1.576 -0.9666 1940390 CBMicro_029631 CCOc1cc(C=O)cc(I)c1OCc2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J14 compound treatment 0.309 -0.0309 -2.56 0.313 -0.0259 -2.3 -3.4354 -0.9985 1940391 CBMicro_029632 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cccc4ccccc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J15 compound treatment 0.321 -0.0189 -1.57 0.325 -0.0139 -1.23 -1.979 -0.993 1940392 CBMicro_029633 COC(=O)/C(=C\c1ccc(Cl)cc1)/[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J16 compound treatment 0.316 -0.0239 -1.98 0.332 -0.00691 -0.61 -1.8338 -0.8843 1940393 CBMicro_029634 Cc1ccc(cc1)N2C(=O)C(=Cc3ccc(O)cc3)C(=O)N(C2=S)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J17 compound treatment 0.342 0.00213 0.18 0.361 0.0221 1.96 1.5097 0.7679 1425367 CBMicro_029635 COc1ccc(CC(=O)N2CCN(CC2)c3ccc(F)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J18 compound treatment 0.863 0.523 43.43 0.86 0.521 46.18 63.364 0.9995 1940394 CBMicro_029636 COc1ccc(/C=C/2\SC(=S)NC2=O)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J19 compound treatment 0.341 0.00113 0.09 0.359 0.0201 1.78 1.3257 0.7434 1118598 CBMicro_029637 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J20 compound treatment 0.331 -0.00887 -0.74 0.348 0.00909 0.81 0.0494 0.0452 1260878 CBMicro_029638 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3c(Cl)cccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J21 compound treatment 0.462 0.122 10.14 0.48 0.141 12.5 16.0113 0.9946 1940395 CBMicro_029639 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(/C=C/C(=O)c3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J22 compound treatment 0.319 -0.0209 -1.73 0.313 -0.0259 -2.3 -2.8484 -0.9904 1781239 CBMicro_029640 Cn1c(=O)cc(NC2CCCCC2)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J23 positive control 0.085 -0.255 -21.16 0.087 -0.252 -22.32 -30.7472 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 J24 positive control 0.09 -0.25 -20.74 0.095 -0.244 -21.62 -29.9524 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K01 mock treatment 0.338 -0.00187 -0.15 0.341 0.00209 0.19 0.0216 0.0895 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K02 mock treatment 0.342 0.00213 0.18 0.344 0.00509 0.45 0.4444 0.9165 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K03 compound treatment 0.327 -0.0129 -1.07 0.325 -0.0139 -1.23 -1.6268 -0.9975 1406639 CBMicro_029641 CCC1CCc2c(C(=O)OC)c(NC(=O)c3ccccc3Br)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K04 compound treatment 0.335 -0.00487 -0.4 0.329 -0.00991 -0.88 -0.9065 -0.938 1940396 CBMicro_029642 Ic1ccccc1/C=N/N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K05 compound treatment 0.323 -0.0169 -1.4 0.315 -0.0239 -2.12 -2.4882 -0.9798 1940397 CBMicro_029643 CCC1(C2C(C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])C4(CC)C1=O)C(=C4c5ccccc5)c6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K06 compound treatment 0.341 0.00113 0.09 0.339 9.38E-5 0.01 0.0724 0.7666 1493689 CBMicro_029644 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(cc3)c4nnc(o4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K07 compound treatment 0.342 0.00213 0.18 0.34 0.00109 0.1 0.1938 0.9598 1940398 CBMicro_029645 Fc1ccc(/C=C/C(=O)n2cnc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K08 compound treatment 0.368 0.0281 2.34 0.368 0.0291 2.58 3.4747 0.9988 1242739 CBMicro_029646 Cc1cc2N(C(=O)CN3C(=O)c4ccccc4C3=O)C(C)(C)c5ssc(=S)c5-c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K09 compound treatment 0.352 0.0121 1.01 0.377 0.0381 3.38 3.0994 0.8798 1940399 CBMicro_029647 COc1cc(/C=C/2\SC(=N)NC2=O)ccc1OCC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K10 compound treatment 0.334 -0.00587 -0.49 0.333 -0.00591 -0.52 -0.7145 -0.9994 1940400 CBMicro_029648 Cc1cc(OCCCN2CCOCC2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K11 compound treatment 0.344 0.00413 0.34 0.349 0.0101 0.89 0.8752 0.9135 1940401 CBMicro_029649 CC(NC(=O)C(=O)Nc1ccc(F)cc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K12 compound treatment 0.365 0.0251 2.09 0.39 0.0511 4.53 4.6772 0.9381 1940402 CBMicro_029650 CCOC(=O)C1=CSC2(S1)C=C(SC3=C2c4cc(C)ccc4N(C(=O)CC)C3(C)C)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K13 compound treatment 0.326 -0.0139 -1.15 0.328 -0.0109 -0.97 -1.4975 -0.9962 1940403 CBMicro_029651 CCCCNc1cc(=O)n(C)c(=O)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K14 compound treatment 0.334 -0.00587 -0.49 0.337 -0.00191 -0.17 -0.4638 -0.8998 1521964 CBMicro_029652 Cc1ccc(cc1)N(CC(=O)O)S(=O)(=O)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K15 compound treatment 0.343 0.00313 0.26 0.351 0.0121 1.07 0.9418 0.8539 1569221 CBMicro_029653 Clc1ccc(C(=O)NCCN2CCN(CC2)C(=O)c3ccc(Cl)cc3Cl)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K16 compound treatment 0.316 -0.0239 -1.98 0.321 -0.0179 -1.59 -2.5231 -0.9939 1373721 CBMicro_029654 COc1ccccc1CC(=O)Nc2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K17 compound treatment 0.311 -0.0289 -2.4 0.307 -0.0319 -2.83 -3.694 -0.9966 1940404 CBMicro_029655 CC(C)c1ccc(C)cc1OC(=O)c2ccccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K18 compound treatment 0.168 -0.172 -14.27 0.174 -0.165 -14.61 -20.423 -0.9999 1940405 CBMicro_029656 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)c4ccc([N+](=O)[O-])c(C)c4)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K19 compound treatment 0.343 0.00313 0.26 0.347 0.00809 0.72 0.6911 0.9058 1940406 CBMicro_029657 CCc1nnc(NC(=O)c2ccc(Cl)cc2Cl)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K20 compound treatment 0.336 -0.00387 -0.32 0.335 -0.00391 -0.35 -0.4718 -0.9993 1530807 CBMicro_029658 CC1CC(Nc2ccccc2)c3cccc(C)c3N1C(=O)c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K21 compound treatment 0.322 -0.0179 -1.48 0.327 -0.0119 -1.06 -1.7949 -0.9861 1940407 CBMicro_029659 COC(=O)c1sccc1NS(=O)(=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K22 compound treatment 0.336 -0.00387 -0.32 0.331 -0.00791 -0.7 -0.7224 -0.9374 1940408 CBMicro_029660 COC(=O)c1ccc(/C=C/2\S/C(=N\Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K23 positive control 0.087 -0.253 -20.99 0.086 -0.253 -22.41 -30.6925 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 K24 positive control 0.092 -0.248 -20.58 0.094 -0.245 -21.7 -29.8977 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L01 mock treatment 0.338 -0.00187 -0.15 0.34 0.00109 0.1 -0.041 -0.2245 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L02 mock treatment 0.342 0.00213 0.18 0.345 0.00609 0.54 0.5071 0.8922 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L03 compound treatment 0.345 0.00513 0.43 0.34 0.00109 0.1 0.3699 0.8463 1940409 CBMicro_029661 CCN(CC)C(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L04 compound treatment 0.324 -0.0159 -1.32 0.32 -0.0189 -1.68 -2.1162 -0.9929 1371420 CBMicro_029662 COc1ccc(CCNS(=O)(=O)c2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L05 compound treatment 0.349 0.00913 0.76 0.356 0.0171 1.51 1.6073 0.9488 1233503 CBMicro_029663 CCOc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3cccc(C)c3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L06 compound treatment 0.342 0.00213 0.18 0.345 0.00609 0.54 0.5071 0.8922 1940410 CBMicro_029664 [O-][N+](=O)c1cccc2C(=O)N(C(=O)c21)c3ccc(cc3)C(=O)Nc4nccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L07 compound treatment 0.324 -0.0159 -1.32 0.328 -0.0109 -0.97 -1.6149 -0.9884 1168690 CBMicro_029665 Nc1cccc(c1)C(=O)Nc2ccc(cc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L08 compound treatment 0.334 -0.00587 -0.49 0.328 -0.0109 -0.97 -1.0278 -0.9497 1196346 CBMicro_029666 CC(=O)Nc1cccc(NC(=O)CC(c2ccccc2)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L09 compound treatment 0.345 0.00513 0.43 0.347 0.00809 0.72 0.8085 0.9691 1455382 CBMicro_029667 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N2CCc3ccccc3C2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L10 compound treatment 0.365 0.0251 2.09 0.355 0.0161 1.43 2.4839 0.9828 1453157 CBMicro_029668 Clc1ccc(NC(=O)c2ccc(Br)cc2)cc1c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L11 compound treatment 0.35 0.0101 0.84 0.333 -0.00591 -0.52 0.2247 0.2268 1940411 CBMicro_029669 COC(=O)c1ccc(/C=C(/C#N)\C(=O)Nc2ccc(O)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L12 compound treatment 0.348 0.00813 0.68 0.34 0.00109 0.1 0.546 0.8004 1576491 CBMicro_029670 COc1ccc(CC(=O)Nc2ccc(Br)c(C)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L13 compound treatment 0.371 0.0311 2.58 0.368 0.0291 2.58 3.6508 1.0 1940412 CBMicro_029671 Cc1onc(c1C(=O)N2CCN(CC2)c3ccc(Cl)cc3[N+](=O)[O-])c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L14 compound treatment 0.35 0.0101 0.84 0.346 0.00709 0.63 1.0394 0.9897 1601265 CBMicro_029672 Cc1ccc(cc1)N(CC(=O)NC2CCCCC2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L15 compound treatment 0.331 -0.00887 -0.74 0.328 -0.0109 -0.97 -1.2039 -0.991 1497563 CBMicro_029673 Cc1nnc(NS(=O)(=O)c2ccc(F)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L16 compound treatment 0.33 -0.00987 -0.82 0.326 -0.0129 -1.14 -1.388 -0.9866 1260073 CBMicro_029674 Brc1cccc(c1)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L17 compound treatment 0.375 0.0351 2.92 0.385 0.0461 4.08 4.9509 0.9864 1940413 CBMicro_029675 COc1ccc(CC(=O)N/N=C/c2ccc(o2)c3cc(Cl)ccc3C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L18 compound treatment 0.325 -0.0149 -1.23 0.331 -0.00791 -0.7 -1.3682 -0.964 1940414 CBMicro_029676 COc1cccc(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L19 compound treatment 0.321 -0.0189 -1.57 0.32 -0.0189 -1.68 -2.2923 -0.9994 1528381 CBMicro_029677 CCOc1ccccc1NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L20 compound treatment 0.34 1.33E-4 0.01 0.344 0.00509 0.45 0.327 0.7242 1659490 CBMicro_029678 COc1cccc2cc(C(=O)Nc3ccccc3C(=O)O)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L21 compound treatment 0.321 -0.0189 -1.57 0.318 -0.0209 -1.85 -2.4176 -0.9965 1740545 CBMicro_029679 Clc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L22 compound treatment 0.351 0.0111 0.92 0.352 0.0131 1.16 1.4741 0.9936 1940415 CBMicro_029680 CCOC(=O)C(=Cc1cc(OC)c(OC)cc1Br)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L23 positive control 0.087 -0.253 -20.99 0.087 -0.252 -22.32 -30.6298 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 L24 positive control 0.092 -0.248 -20.58 0.094 -0.245 -21.7 -29.8977 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M01 mock treatment 0.336 -0.00387 -0.32 0.342 0.00309 0.27 -0.0331 -0.0784 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M02 mock treatment 0.338 -0.00187 -0.15 0.339 9.38E-5 0.01 -0.1037 -0.6682 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M03 compound treatment 0.335 -0.00487 -0.4 0.326 -0.0129 -1.14 -1.0945 -0.9022 1940416 CBMicro_029681 Cc1ccc(cc1NC(=O)c2ccc(cc2Cl)[N+](=O)[O-])S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M04 compound treatment 0.316 -0.0239 -1.98 0.312 -0.0269 -2.38 -3.0871 -0.9958 1940417 CBMicro_029682 CCCCNCCOc1cc(C)c(Cl)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M05 compound treatment 0.332 -0.00787 -0.65 0.337 -0.00191 -0.17 -0.5813 -0.8617 1940418 CBMicro_029683 COC(=O)c1ccc(cc1)N2C(=O)C3C(C4C=CC3C5CC54)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M06 compound treatment 0.33 -0.00987 -0.82 0.336 -0.00291 -0.26 -0.7613 -0.8866 1940419 CBMicro_029684 FC(F)(F)c1ccccc1/C=N/NC(=O)c2ccc(CN3CCOCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M07 compound treatment 0.343 0.00313 0.26 0.339 9.38E-5 0.01 0.1898 0.7293 1222525 CBMicro_029685 CC(C)(C)NC(=O)C1(C)CC2c3ccccc3C1c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M08 compound treatment 0.346 0.00613 0.51 0.348 0.00909 0.81 0.9299 0.9755 1506517 CBMicro_029686 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(cc3)N(Cc4ccccc4)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M09 compound treatment 0.326 -0.0139 -1.15 0.333 -0.00591 -0.52 -1.1841 -0.9364 1940420 CBMicro_029687 O/N=C/1\c2ccccc2-c3c1cccc3C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M10 compound treatment 0.345 0.00513 0.43 0.342 0.00309 0.27 0.4952 0.9773 1940421 CBMicro_029688 COc1ccccc1N2N=C(CC2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M11 compound treatment 0.327 -0.0129 -1.07 0.327 -0.0119 -1.06 -1.5014 -1.0 1940422 CBMicro_029689 Cc1ccc(cc1)C(=O)Nc2nnc[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M12 compound treatment 0.567 0.227 18.86 0.569 0.23 20.39 27.7523 0.9992 1940423 CBMicro_029690 CCOC(=O)C(=Cc1cc(OC)c(O)c(c1)[N+](=O)[O-])C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M13 compound treatment 0.324 -0.0159 -1.32 0.328 -0.0109 -0.97 -1.6149 -0.9884 1940424 CBMicro_029691 CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2cc(ccc2Cl)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M14 compound treatment 0.372 0.0321 2.67 0.364 0.0251 2.22 3.4588 0.9959 1940425 CBMicro_029692 COc1ccc(OC)c(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M15 compound treatment 0.331 -0.00887 -0.74 0.337 -0.00191 -0.17 -0.64 -0.8474 1779916 CBMicro_029693 CC(C)OC(=O)C(C)Nc1n[nH]c(=S)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M16 compound treatment 0.319 -0.0209 -1.73 0.327 -0.0119 -1.06 -1.971 -0.9717 1498444 CBMicro_029694 Cc1ccc(cc1C)N2C(=O)c3cccnc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M17 compound treatment 0.329 -0.0109 -0.9 0.335 -0.00391 -0.35 -0.8827 -0.9135 1462744 CBMicro_029695 CCOC(=O)c1cc2COC(C)(C)Cc2nc1NC(=S)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M18 compound treatment 0.338 -0.00187 -0.15 0.332 -0.00691 -0.61 -0.5424 -0.859 1940426 CBMicro_029696 Cc1cccc(N/C(=N\C(=O)c2ccccc2)/Nc3nc(C)cc(C)n3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M19 compound treatment 0.36 0.0201 1.67 0.364 0.0251 2.22 2.7544 0.9901 1730791 CBMicro_029697 Cc1ccccc1C(=O)Nc2nc3ccc(Cl)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M20 compound treatment 0.327 -0.0129 -1.07 0.323 -0.0159 -1.41 -1.7521 -0.9906 1940427 CBMicro_029698 CC(C)c1ccccc1OCCCN2CCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M21 compound treatment 0.348 0.00813 0.68 0.35 0.0111 0.98 1.1726 0.9832 1298098 CBMicro_029699 CCOC(=O)c1c(NC(=O)c2cccc(OC)c2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M22 compound treatment 0.333 -0.00687 -0.57 0.334 -0.00491 -0.43 -0.7105 -0.9911 1560952 CBMicro_029700 COc1cc(NC(=O)C2CCCCC2)c3ncccc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M23 positive control 0.086 -0.254 -21.08 0.089 -0.25 -22.15 -30.5632 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 M24 positive control 0.091 -0.249 -20.66 0.094 -0.245 -21.7 -29.9564 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N01 mock treatment 0.344 0.00413 0.34 0.343 0.00409 0.36 0.4992 0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N02 mock treatment 0.343 0.00313 0.26 0.347 0.00809 0.72 0.6911 0.9058 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N03 compound treatment 0.327 -0.0129 -1.07 0.33 -0.00891 -0.79 -1.3134 -0.9889 1940428 CBMicro_029701 Oc1ccc(NC(=O)/C(=C\c2ccc(Cl)cc2)/C#N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N04 compound treatment 0.341 0.00113 0.09 0.35 0.0111 0.98 0.7617 0.7713 1507154 CBMicro_029702 CCSc1nnc(NC(=O)c2cnccn2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N05 compound treatment 0.331 -0.00887 -0.74 0.328 -0.0109 -0.97 -1.2039 -0.991 1190088 CBMicro_029703 CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N06 compound treatment 0.345 0.00513 0.43 0.349 0.0101 0.89 0.9339 0.9425 1940429 CBMicro_029704 CC1=C(C(NC(=S)N1)c2ccc(C)cc2)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N07 compound treatment 0.327 -0.0129 -1.07 0.323 -0.0159 -1.41 -1.7521 -0.9906 1159063 CBMicro_029705 Cc1cc(C)c(OCCN2CCCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N08 compound treatment 0.32 -0.0199 -1.65 0.319 -0.0199 -1.76 -2.4137 -0.9994 1940430 CBMicro_029706 Cc1ccc(Cl)c(OCCNC(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N09 compound treatment 0.337 -0.00287 -0.24 0.334 -0.00491 -0.43 -0.4757 -0.9598 1537383 CBMicro_029707 CC(C1CC(=O)N(C1=O)c2ccc(I)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N10 compound treatment 0.341 0.00113 0.09 0.339 9.38E-5 0.01 0.0724 0.7666 1041387 CBMicro_029708 S=C(Nc1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N11 compound treatment 0.338 -0.00187 -0.15 0.334 -0.00491 -0.43 -0.417 -0.9035 1727731 CBMicro_029709 Clc1ccc(NC(=O)c2cc3cccc(CC=C)c3oc2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N12 compound treatment 0.308 -0.0319 -2.65 0.316 -0.0229 -2.03 -3.3061 -0.9914 1940431 CBMicro_029710 Cc1ccc(OCCCNC(C)(C)C)c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N13 compound treatment 0.341 0.00113 0.09 0.345 0.00609 0.54 0.4484 0.818 1619206 CBMicro_029711 CC(=O)Nc1ccccc1C(=O)N2CCN(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N14 compound treatment 0.339 -8.67E-4 -0.07 0.333 -0.00591 -0.52 -0.421 -0.7968 1866008 CBMicro_029712 COc1ccc2oc(=O)c(cc2c1)C(=O)Nc3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N15 compound treatment 0.335 -0.00487 -0.4 0.328 -0.0109 -0.97 -0.9691 -0.9251 1295881 CBMicro_029713 COc1ccc(NC(=O)Cc2ccccc2OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N16 compound treatment 0.339 -8.67E-4 -0.07 0.328 -0.0109 -0.97 -0.7343 -0.7576 1940432 CBMicro_029714 Cc1ccc2oc(nc2c1)c3ccc(Cl)c(NC(=O)c4ccc(o4)[N+](=O)[O-])c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N17 compound treatment 0.322 -0.0179 -1.48 0.335 -0.00391 -0.35 -1.2936 -0.8493 1940433 CBMicro_029715 O=C(CSc1nc2ccccc2s1)NNC(=S)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N18 compound treatment 0.336 -0.00387 -0.32 0.337 -0.00191 -0.17 -0.3464 -0.9551 1311726 CBMicro_029716 COc1cc2ccccc2cc1C(=O)Nc3cc(ccc3C)c4nc5cc(C)ccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N19 compound treatment 0.332 -0.00787 -0.65 0.333 -0.00591 -0.52 -0.8319 -0.994 1940434 CBMicro_029717 OC(=O)c1ccc(C(=O)Nc2ccccc2Br)c(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N20 compound treatment 0.327 -0.0129 -1.07 0.332 -0.00691 -0.61 -1.1881 -0.9651 1555212 CBMicro_029718 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(C)c(Cl)c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N21 compound treatment 0.36 0.0201 1.67 0.364 0.0251 2.22 2.7544 0.9901 1940435 CBMicro_029719 C=CCc1cccc2cc(C(=O)NNC(=O)CC#N)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N22 compound treatment 0.348 0.00813 0.68 0.345 0.00609 0.54 0.8593 0.9939 1176953 CBMicro_029720 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N23 positive control 0.087 -0.253 -20.99 0.088 -0.251 -22.24 -30.5672 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 N24 positive control 0.091 -0.249 -20.66 0.092 -0.247 -21.88 -30.0817 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O01 mock treatment 0.342 0.00213 0.18 0.344 0.00509 0.45 0.4444 0.9165 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O02 mock treatment 0.341 0.00113 0.09 0.343 0.00409 0.36 0.3231 0.862 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O03 compound treatment 0.336 -0.00387 -0.32 0.337 -0.00191 -0.17 -0.3464 -0.9551 1940436 CBMicro_029721 [O-][N+](=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O04 compound treatment 0.346 0.00613 0.51 0.349 0.0101 0.89 0.9926 0.9643 1306191 CBMicro_029722 COc1ccc(CC(=O)N2CCN(CC2)c3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O05 compound treatment 0.331 -0.00887 -0.74 0.336 -0.00291 -0.26 -0.7026 -0.901 1666819 CBMicro_029723 CCSC(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O06 compound treatment 0.338 -0.00187 -0.15 0.339 9.38E-5 0.01 -0.1037 -0.6682 1940437 CBMicro_029724 Clc1ccc(SCCCN2CCOCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O07 compound treatment 0.329 -0.0109 -0.9 0.327 -0.0119 -1.06 -1.384 -0.997 1775865 CBMicro_029725 Cc1[nH]c(=O)c(C#N)c2CC(C)(C)OCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O08 compound treatment 0.31 -0.0299 -2.48 0.316 -0.0229 -2.03 -3.1887 -0.9951 1940438 CBMicro_029726 CC(C)(C)NCCCCOc1cc(Cl)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O09 compound treatment 0.331 -0.00887 -0.74 0.335 -0.00391 -0.35 -0.7653 -0.9408 1165185 CBMicro_029727 OC(=O)Cc1csc(n1)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O10 compound treatment 0.39 0.0501 4.16 0.392 0.0531 4.71 6.2701 0.9981 1940439 CBMicro_029728 COC(=O)C1=C(C)N/C(=C/c2ccccc2)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O11 compound treatment 0.327 -0.0129 -1.07 0.329 -0.00991 -0.88 -1.3761 -0.9953 1940440 CBMicro_029729 Cc1cc(C)n(n1)S(=O)(=O)c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O12 compound treatment 0.361 0.0211 1.75 0.36 0.0211 1.87 2.5624 0.9995 1940441 CBMicro_029730 CC(=O)c1cccc(NC(=O)c2cc3cccc(CC=C)c3oc2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O13 compound treatment 0.334 -0.00587 -0.49 0.332 -0.00691 -0.61 -0.7772 -0.9936 1940442 CBMicro_029731 [O-][N+](=O)c1cccc(/C=C/C(=O)NCCN2CCOCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O14 compound treatment 0.342 0.00213 0.18 0.339 9.38E-5 0.01 0.1311 0.7395 1940443 CBMicro_029732 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCCc2ccccc2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O15 compound treatment 0.361 0.0211 1.75 0.378 0.0391 3.46 3.6904 0.9503 1488327 CBMicro_029733 Clc1ccc(C(=O)Nc2cccc(c2)c3nc4ccccc4s3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O16 compound treatment 0.365 0.0251 2.09 0.372 0.0331 2.93 3.5492 0.9861 1364047 CBMicro_029734 Cc1ccc(NCC(O)COc2ccc(OCC(O)CNc3ccc(C)c(C)c3)cc2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O17 compound treatment 0.336 -0.00387 -0.32 0.334 -0.00491 -0.43 -0.5344 -0.9889 1302752 CBMicro_029735 CCCOc1ccc(Cc2c(O)nc(N)nc2O)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O18 compound treatment 0.352 0.0121 1.01 0.353 0.0141 1.25 1.5955 0.9943 1280089 CBMicro_029736 COc1ccc(Cl)cc1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O19 compound treatment 0.348 0.00813 0.68 0.342 0.00309 0.27 0.6713 0.9212 1485216 CBMicro_029737 O=C(Nc1cccc2ccccc12)c3cnccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O20 compound treatment 0.333 -0.00687 -0.57 0.34 0.00109 0.1 -0.3346 -0.5786 1417008 CBMicro_029738 CCOc1ccc(cc1OCC)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O21 compound treatment 0.329 -0.0109 -0.9 0.335 -0.00391 -0.35 -0.8827 -0.9135 1468782 CBMicro_029739 CCOc1cccc2sc(NC(=O)c3ccc(Br)cc3)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O22 compound treatment 0.336 -0.00387 -0.32 0.333 -0.00591 -0.52 -0.5971 -0.9725 1940444 CBMicro_029740 [O-][N+](=O)c1ccccc1Nc2nnc(c3ccccc3)c(n2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O23 positive control 0.086 -0.254 -21.08 0.088 -0.251 -22.24 -30.6259 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 O24 positive control 0.092 -0.248 -20.58 0.093 -0.246 -21.79 -29.9603 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P01 mock treatment 0.342 0.00213 0.18 0.338 -9.06E-4 -0.08 0.0684 0.352 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P02 mock treatment 0.346 0.00613 0.51 0.338 -9.06E-4 -0.08 0.3033 0.5883 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P03 compound treatment 0.341 0.00113 0.09 0.331 -0.00791 -0.7 -0.4289 -0.6067 1940445 CBMicro_029741 Oc1ccccc1/C=N/Nc2ncnc3n(Cc4ccccc4)ncc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P04 compound treatment 0.333 -0.00687 -0.57 0.332 -0.00691 -0.61 -0.8359 -0.9994 1940446 CBMicro_029742 O=C(NNC(=O)c1ccc2C(=O)N(N3C(=O)c4ccccc4C3=O)C(=O)c2c1)c5ccco5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P05 compound treatment 0.332 -0.00787 -0.65 0.342 0.00309 0.27 -0.2679 -0.3783 1130855 CBMicro_029743 CN(C)c1cccc(c1)C(=O)Nc2ccc(Br)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P06 compound treatment 0.346 0.00613 0.51 0.357 0.0181 1.6 1.4939 0.888 1940447 CBMicro_029744 Clc1ccc(NC(=S)NNC(=O)CSc2nc3ccccc3s2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P07 compound treatment 0.331 -0.00887 -0.74 0.329 -0.00991 -0.88 -1.1413 -0.9962 1940448 CBMicro_029745 Ic1ccccc1NC(=O)c2nc[nH]n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P08 compound treatment 0.356 0.0161 1.34 0.346 0.00709 0.63 1.3916 0.9405 1940449 CBMicro_029746 O=C(CC1S/C(=N\c2ccccc2)/N(C1=O)c3ccccc3)Nc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P09 compound treatment 0.335 -0.00487 -0.4 0.338 -9.06E-4 -0.08 -0.3425 -0.8314 1519940 CBMicro_029747 COc1ccccc1NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P10 compound treatment 0.4 0.0601 4.99 0.37 0.0311 2.76 5.4785 0.9608 1940450 CBMicro_029748 [O-][N+](=O)c1cc(/C=N/NC(=O)c2cc3ccccc3o2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P11 compound treatment 0.325 -0.0149 -1.23 0.333 -0.00591 -0.52 -1.2428 -0.9271 1940451 CBMicro_029749 Clc1ccc(NC(=O)NNc2nc(Nc3ccccc3)nc(n2)N4CCOCC4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P12 compound treatment 0.344 0.00413 0.34 0.353 0.0141 1.25 1.1258 0.8692 1689372 CBMicro_029750 COc1ccccc1CC(=O)Nc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P13 compound treatment 0.331 -0.00887 -0.74 0.336 -0.00291 -0.26 -0.7026 -0.901 1655739 CBMicro_029751 CN(C)c1cccc(c1)C(=O)Nc2ccc(F)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P14 compound treatment 0.337 -0.00287 -0.24 0.347 0.00809 0.72 0.3389 0.4485 1940452 CBMicro_029752 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P15 compound treatment 0.345 0.00513 0.43 0.35 0.0111 0.98 0.9965 0.93 1469077 CBMicro_029753 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)N3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P16 compound treatment 0.34 1.33E-4 0.01 0.347 0.00809 0.72 0.515 0.7179 1940453 CBMicro_029754 CCCCOc1ccc(cc1)C(=O)Nc2cccc(NC(=O)c3ccccc3Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P17 compound treatment 0.338 -0.00187 -0.15 0.341 0.00209 0.19 0.0216 0.0895 1940454 CBMicro_029755 [O-][N+](=O)c1ccccc1S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P18 compound treatment 0.183 -0.157 -13.02 0.185 -0.154 -13.64 -18.8531 -0.9997 1940455 CBMicro_029756 COc1ccc(/C=C/2\SC(=S)N(Nc3ccccc3)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P19 compound treatment 0.326 -0.0139 -1.15 0.322 -0.0169 -1.5 -1.8735 -0.9915 1940456 CBMicro_029757 Clc1cccc(OCCCCN2CCOCC2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P20 compound treatment 0.332 -0.00787 -0.65 0.333 -0.00591 -0.52 -0.8319 -0.994 1269121 CBMicro_029758 CCCN(CCC)c1ccc(cc1)C2NC(=O)c3c4CCN(C)Cc4sc3N2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P21 compound treatment 0.338 -0.00187 -0.15 0.338 -9.06E-4 -0.08 -0.1664 -0.9532 1568214 CBMicro_029759 OC(=O)c1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P22 compound treatment 0.334 -0.00587 -0.49 0.334 -0.00491 -0.43 -0.6518 -0.9984 1781935 CBMicro_029760 CCN1C(=C(C(NC1=O)c2ccc(cc2)[N+](=O)[O-])C(=O)OCC=C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P23 positive control 0.089 -0.251 -20.83 0.091 -0.248 -21.97 -30.2618 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.778 P24 positive control 0.094 -0.246 -20.41 0.094 -0.245 -21.7 -29.7803 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A01 mock treatment 0.32 -0.021 -1.75 0.322 -0.0206 -1.83 -2.5264 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A02 mock treatment 0.332 -0.00903 -0.75 0.338 -0.00461 -0.41 -0.8194 -0.9593 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A03 compound treatment 0.333 -0.00803 -0.67 0.334 -0.00861 -0.76 -1.0113 -0.9977 1667357 CBMicro_029761 COc1ccc(CC(=O)Nc2ccc(Br)cc2F)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A04 compound treatment 0.318 -0.023 -1.91 0.318 -0.0246 -2.18 -2.8945 -0.9978 1095009 CBMicro_029762 Cn1c(=O)[nH]c2[nH]c(nc2c1=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A05 compound treatment 0.312 -0.029 -2.41 0.32 -0.0226 -2.0 -3.1214 -0.9958 1940457 CBMicro_029763 COc1ccccc1N2N=C(CC2c3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A06 compound treatment 0.32 -0.021 -1.75 0.326 -0.0166 -1.47 -2.2758 -0.9964 1389897 CBMicro_029764 OC(=O)c1cc(Br)ccc1NC(=O)C2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A07 compound treatment 0.319 -0.022 -1.83 0.332 -0.0106 -0.94 -1.9585 -0.9522 1425268 CBMicro_029765 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A08 compound treatment 0.31 -0.031 -2.58 0.319 -0.0236 -2.09 -3.3015 -0.9947 1940458 CBMicro_029766 CCOc1ccccc1OCCCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A09 compound treatment 0.332 -0.00903 -0.75 0.337 -0.00561 -0.5 -0.882 -0.9801 1781611 CBMicro_029767 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ncccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A10 compound treatment 0.319 -0.022 -1.83 0.323 -0.0196 -1.74 -2.5225 -0.9997 1940459 CBMicro_029768 COc1cc(C=O)cc(Br)c1OCc2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A11 compound treatment 0.321 -0.02 -1.66 0.325 -0.0176 -1.56 -2.2797 -0.9995 1192123 CBMicro_029769 Cc1c(NC(=O)c2cccs2)cccc1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A12 compound treatment 0.363 0.022 1.82 0.364 0.0214 1.9 2.6297 0.9998 1592642 CBMicro_029770 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCc2ccc(Cl)cc2Cl)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A13 compound treatment 0.328 -0.013 -1.08 0.331 -0.0116 -1.03 -1.4928 -0.9997 1940460 CBMicro_029771 Cc1ccc(C)c(OCCCCN2CCOCC2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A14 compound treatment 0.351 0.00997 0.83 0.352 0.00939 0.83 1.1733 1.0 1940461 CBMicro_029772 COc1ccc(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A15 compound treatment 0.362 0.021 1.74 0.365 0.0224 1.98 2.6337 0.9979 1610140 CBMicro_029773 Cc1ccccc1CNC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A16 compound treatment 0.325 -0.016 -1.33 0.329 -0.0136 -1.21 -1.7943 -0.9988 1940462 CBMicro_029774 OC(=O)C1=CNC=C(C1c2ccc(O)cc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A17 compound treatment 0.322 -0.019 -1.58 0.325 -0.0176 -1.56 -2.221 -1.0 1940463 CBMicro_029775 COc1ccc(C=C2C(=O)N(C(=O)N(C2=O)c3ccccc3)c4ccccc4)cc1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A18 compound treatment 0.319 -0.022 -1.83 0.328 -0.0146 -1.3 -2.2091 -0.9857 1688398 CBMicro_029776 Cc1ccc(cc1N2C(=O)c3ccccc3C2=O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A19 compound treatment 0.324 -0.017 -1.41 0.328 -0.0146 -1.3 -1.9156 -0.999 1940464 CBMicro_029777 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nc2c[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A20 compound treatment 0.323 -0.018 -1.5 0.328 -0.0146 -1.3 -1.9743 -0.9974 1351542 CBMicro_029778 Cc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A21 compound treatment 0.339 -0.00203 -0.17 0.322 -0.0206 -1.83 -1.4111 -0.7692 1940465 CBMicro_029779 COc1ccc(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A22 compound treatment 0.323 -0.018 -1.5 0.323 -0.0196 -1.74 -2.2877 -0.9972 1166087 CBMicro_029780 CC(C)(C)C(C)(O)C#CCN1CCOCC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A23 positive control 0.083 -0.258 -21.42 0.084 -0.259 -22.92 -31.3534 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 A24 positive control 0.085 -0.256 -21.26 0.087 -0.256 -22.65 -31.048 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B01 mock treatment 0.334 -0.00703 -0.58 0.328 -0.0146 -1.3 -1.3286 -0.9353 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B02 mock treatment 0.351 0.00997 0.83 0.342 -6.13E-4 -0.05 0.5467 0.6593 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B03 compound treatment 0.315 -0.026 -2.16 0.327 -0.0156 -1.38 -2.5066 -0.9768 1653413 CBMicro_029781 CCOc1ccccc1NC(=O)COc2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B04 compound treatment 0.318 -0.023 -1.91 0.327 -0.0156 -1.38 -2.3305 -0.9874 1128140 CBMicro_029782 CCOc1ccc2cc(ccc2c1)S(=O)(=O)N3CCCCC3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B05 compound treatment 0.329 -0.012 -1.0 0.34 -0.00261 -0.23 -0.8701 -0.8485 1940466 CBMicro_029783 Nc1cccc(c1)c2nnc(o2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B06 compound treatment 0.301 -0.04 -3.32 0.314 -0.0286 -2.54 -4.1431 -0.9911 1940467 CBMicro_029784 CN1C(=O)C(=CNC(C)(CO)CO)C(=O)N(C)C1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B07 compound treatment 0.382 0.041 3.4 0.382 0.0394 3.49 4.8731 0.9999 1547912 CBMicro_029785 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccc(Br)o4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B08 compound treatment 0.321 -0.02 -1.66 0.334 -0.00861 -0.76 -1.7158 -0.9376 1125622 CBMicro_029786 CC1(C)CC(=O)C=C(C1)Nc2ccc3CCCc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B09 compound treatment 0.341 -3.33E-5 0.0 0.36 0.0174 1.54 1.0876 0.7058 1940468 CBMicro_029787 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cccc4ccccc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B10 compound treatment 0.324 -0.017 -1.41 0.333 -0.00961 -0.85 -1.6023 -0.9706 1507316 CBMicro_029788 Brc1ccc(nc1)N2C(=O)c3cccc4cccc(C2=O)c34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B11 compound treatment 0.384 0.043 3.57 0.395 0.0524 4.64 5.8051 0.9915 1940469 CBMicro_029789 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cccc(c2)c3nc4cc(CC)ccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B12 compound treatment 0.424 0.083 6.89 0.418 0.0754 6.68 9.5946 0.9999 1940470 CBMicro_029790 COc1cc(/C=C/c2cc([nH]c(=O)n2)C(F)(F)F)ccc1OCc3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B13 compound treatment 0.343 0.00197 0.16 0.353 0.0104 0.92 0.7664 0.8197 1648564 CBMicro_029791 COc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B14 compound treatment 0.321 -0.02 -1.66 0.334 -0.00861 -0.76 -1.7158 -0.9376 1617447 CBMicro_029792 Cc1ccccc1CN2CCN(Cc3ccc(F)cc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B15 compound treatment 0.331 -0.01 -0.83 0.336 -0.00661 -0.59 -1.0034 -0.9852 1485478 CBMicro_029793 Cc1nc2ccccc2c(=O)n1c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B16 compound treatment 0.345 0.00397 0.33 0.345 0.00239 0.21 0.3824 0.9771 1684177 CBMicro_029794 CC(C)N(C(C)C)C(=O)c1ccc(cc1)c2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B17 compound treatment 0.323 -0.018 -1.5 0.339 -0.00361 -0.32 -1.285 -0.8394 1940471 CBMicro_029795 [O-][N+](=O)c1ccc(C(=O)Nc2cccc(Br)c2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B18 compound treatment 0.351 0.00997 0.83 0.35 0.00739 0.65 1.048 0.9933 1940472 CBMicro_029796 CCN(CC)c1ccc(NC=C2C(=O)N(C)C(=S)N(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B19 compound treatment 0.334 -0.00703 -0.58 0.338 -0.00461 -0.41 -0.7019 -0.9848 1940473 CBMicro_029797 CC1CCCCN1C(=O)/C=C/c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B20 compound treatment 0.362 0.021 1.74 0.373 0.0304 2.69 3.135 0.9777 1940474 CBMicro_029798 COc1cccc(/C=C/2\N=C(OC2=O)c3cccs3)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B21 compound treatment 0.35 0.00897 0.74 0.351 0.00839 0.74 1.052 1.0 1650363 CBMicro_029799 COC(=O)c1c(N)sc2CCCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B22 compound treatment 0.334 -0.00703 -0.58 0.336 -0.00661 -0.59 -0.8273 -1.0 1940475 CBMicro_029800 C=CCNCC1OCc2ccccc2CO1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B23 positive control 0.082 -0.259 -21.5 0.084 -0.259 -22.92 -31.4121 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 B24 positive control 0.083 -0.258 -21.42 0.085 -0.258 -22.83 -31.2907 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C01 mock treatment 0.342 9.67E-4 0.08 0.34 -0.00261 -0.23 -0.107 -0.4366 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C02 mock treatment 0.351 0.00997 0.83 0.346 0.00339 0.3 0.7973 0.9059 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C03 compound treatment 0.314 -0.027 -2.24 0.34 -0.00261 -0.23 -1.7507 -0.7759 1940476 CBMicro_029801 CC(=O)c1c(C)nc(C)c(C(=O)C)c1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C04 compound treatment 0.332 -0.00903 -0.75 0.347 0.00439 0.39 -0.2554 -0.3023 1387394 CBMicro_029802 COc1ccccc1CNC(=O)c2cc(Cl)ccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C05 compound treatment 0.331 -0.01 -0.83 0.312 -0.0306 -2.71 -2.5074 -0.8835 1940477 CBMicro_029803 O=C(C(c1ccccc1)c2ccccc2)C/3C(=O)c4ccccc4\C3=N\N=C\c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C06 compound treatment 0.329 -0.012 -1.0 0.34 -0.00261 -0.23 -0.8701 -0.8485 1940478 CBMicro_029804 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCc2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C07 compound treatment 0.349 0.00797 0.66 0.343 3.87E-4 0.03 0.4919 0.7428 1940479 CBMicro_029805 CN(C)c1ccc(/C=N/NC(=O)c2ccc(CN3CCOCC3)cc2)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C08 compound treatment 0.343 0.00197 0.16 0.349 0.00639 0.57 0.5157 0.8754 1405979 CBMicro_029806 Cc1cc(Br)ccc1N2C(=O)c3ccc(cc3C2=O)S(=O)(=O)c4ccc(cc4)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C09 compound treatment 0.343 0.00197 0.16 0.345 0.00239 0.21 0.265 0.9918 1345712 CBMicro_029807 Cc1ccc(cc1)N(CC(=O)N2CCOCC2)S(=O)(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C10 compound treatment 0.331 -0.01 -0.83 0.34 -0.00261 -0.23 -0.7527 -0.8707 1467596 CBMicro_029808 CC(C1CC(=O)N(C1=O)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C11 compound treatment 0.328 -0.013 -1.08 0.337 -0.00561 -0.5 -1.1168 -0.9378 1940480 CBMicro_029809 Fc1ccccc1NCN2C(=O)S/C(=C/c3ccccc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C12 compound treatment 0.352 0.011 0.91 0.357 0.0144 1.28 1.5453 0.9864 1243511 CBMicro_029810 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4-c5c(ssc5=S)C3(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C13 compound treatment 0.333 -0.00803 -0.67 0.363 0.0204 1.81 0.806 0.4185 1940481 CBMicro_029811 N/C(=N\C(=O)c1ccc(F)cc1)/Nc2nc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C14 compound treatment 0.344 0.00297 0.25 0.346 0.00339 0.3 0.3864 0.9952 1940482 CBMicro_029812 COc1ccc(C=C2C(=O)N(C(=S)N(C2=O)c3ccc(C)cc3)c4ccc(C)cc4)cc1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C15 compound treatment 0.336 -0.00503 -0.42 0.349 0.00639 0.57 0.1048 0.1489 1692402 CBMicro_029813 COc1ccc(OC)c(NC(=O)c2cc3cccc(CC=C)c3oc2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C16 compound treatment 0.343 0.00197 0.16 0.349 0.00639 0.57 0.5157 0.8754 1362404 CBMicro_029814 CN(C)c1cccc(c1)C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C17 compound treatment 0.338 -0.00303 -0.25 0.345 0.00239 0.21 -0.0285 -0.0866 1484068 CBMicro_029815 CC(C)N(C(C)C)C(=O)c1ccc(cc1)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C18 compound treatment 0.338 -0.00303 -0.25 0.345 0.00239 0.21 -0.0285 -0.0866 1940483 CBMicro_029816 COc1cc2C=C(C)OS(=O)(=O)c2cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C19 compound treatment 0.342 9.67E-4 0.08 0.345 0.00239 0.21 0.2063 0.9119 1725957 CBMicro_029817 Nc1cccc(c1)C(=O)Nc2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C20 compound treatment 0.361 0.02 1.66 0.354 0.0114 1.01 1.8857 0.9717 1940484 CBMicro_029818 CN(C)S(=O)(=O)c1ccc(C)c(N2CCc3cnn(c23)S(=O)(=O)c4ccc(Cl)cc4)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C21 compound treatment 0.351 0.00997 0.83 0.36 0.0174 1.54 1.6746 0.9575 1940485 CBMicro_029819 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)Nc3ccc(Cl)c(c3)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C22 compound treatment 0.339 -0.00203 -0.17 0.341 -0.00161 -0.14 -0.2204 -0.9966 1940486 CBMicro_029820 CCN1C(=O)/C(=C/c2cccs2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C23 positive control 0.081 -0.26 -21.59 0.083 -0.26 -23.01 -31.5335 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 C24 positive control 0.084 -0.257 -21.34 0.091 -0.252 -22.3 -30.856 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D01 mock treatment 0.34 -0.00103 -0.09 0.343 3.87E-4 0.03 -0.0364 -0.394 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D02 mock treatment 0.346 0.00497 0.41 0.344 0.00139 0.12 0.3785 0.8797 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D03 compound treatment 0.33 -0.011 -0.92 0.333 -0.00961 -0.85 -1.2501 -0.9993 1940487 CBMicro_029821 [O-][N+](=O)c1ccccc1/C=N/NC(=O)CSc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D04 compound treatment 0.319 -0.022 -1.83 0.334 -0.00861 -0.76 -1.8332 -0.9249 1602439 CBMicro_029822 CCOc1ccccc1NC(=O)COc2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D05 compound treatment 0.347 0.00597 0.5 0.343 3.87E-4 0.03 0.3745 0.7543 1940488 CBMicro_029823 CC(=CCCC1=CCC2(C)C(C1)C(=O)NNC2=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D06 compound treatment 0.302 -0.039 -3.24 0.316 -0.0266 -2.36 -3.9591 -0.9878 1940489 CBMicro_029824 CC(CO)(CO)N/C=C/1\C(=O)NC(=S)N(C1=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D07 compound treatment 0.365 0.024 1.99 0.369 0.0264 2.34 3.0605 0.9968 1147842 CBMicro_029825 CCOc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccccc3)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D08 compound treatment 0.343 0.00197 0.16 0.351 0.00839 0.74 0.641 0.8423 1940490 CBMicro_029826 NC(=O)N/N=C/1\c2ccccc2-c3c1cccc3C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D09 compound treatment 0.333 -0.00803 -0.67 0.34 -0.00261 -0.23 -0.6353 -0.8999 1782135 CBMicro_029827 CC1=C(C(NC(=O)N1)c2ccc(cc2)[N+](=O)[O-])C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D10 compound treatment 0.336 -0.00503 -0.42 0.334 -0.00861 -0.76 -0.8352 -0.9598 1940491 CBMicro_029828 CCCc1c(O)nc(SCC(=O)O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D11 compound treatment 0.543 0.202 16.77 0.564 0.221 19.62 25.7294 0.9969 1940492 CBMicro_029829 CS(=O)(=O)N1CCN(CC1)c2ccc([N+](=O)[O-])c(c2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D12 compound treatment 0.323 -0.018 -1.5 0.341 -0.00161 -0.14 -1.1597 -0.7711 1427096 CBMicro_029830 COc1ccccc1NC(=O)c2cc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D13 compound treatment 0.326 -0.015 -1.25 0.343 3.87E-4 0.03 -0.8582 -0.6874 1940493 CBMicro_029831 O=C(CSc1nnnn1c2ccccc2)NCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D14 compound treatment 0.334 -0.00703 -0.58 0.334 -0.00861 -0.76 -0.9526 -0.9913 1940494 CBMicro_029832 CC(=O)Oc1ccc(NC(=O)CC2SC(=N)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D15 compound treatment 0.338 -0.00303 -0.25 0.335 -0.00761 -0.67 -0.6551 -0.9097 1940495 CBMicro_029833 [O-][N+](=O)c1ccccc1C(=O)NCCCn2ccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D16 compound treatment 0.338 -0.00303 -0.25 0.338 -0.00461 -0.41 -0.4671 -0.9729 1121328 CBMicro_029834 OC(=O)c1ccc(Br)c(c1)S(=O)(=O)Nc2ccc(NC(=O)c3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D17 compound treatment 0.345 0.00397 0.33 0.343 3.87E-4 0.03 0.2571 0.7766 1427908 CBMicro_029835 NC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D18 compound treatment 0.378 0.037 3.07 0.373 0.0304 2.69 4.0743 0.9979 1407917 CBMicro_029836 Brc1ccc(cc1)N(CC(=O)Nc2cccc3cccnc23)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D19 compound treatment 0.375 0.034 2.82 0.378 0.0354 3.14 4.2115 0.9986 1940496 CBMicro_029837 CCOC(=O)CSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D20 compound treatment 0.357 0.016 1.33 0.383 0.0404 3.58 3.4682 0.9087 1940497 CBMicro_029838 COc1ccccc1OCCOc2ccccc2/C=N/n3cnnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D21 compound treatment 0.344 0.00297 0.25 0.338 -0.00461 -0.41 -0.1149 -0.2408 1229894 CBMicro_029839 CN(Cc1ccccc1)C(=O)COc2ccc(Cl)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D22 compound treatment 0.338 -0.00303 -0.25 0.342 -6.13E-4 -0.05 -0.2165 -0.8403 1940498 CBMicro_029840 CCCCOc1ccc(cc1)C(=O)O/N=C\2/CCc3cc(OC)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D23 positive control 0.083 -0.258 -21.42 0.084 -0.259 -22.92 -31.3534 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 D24 positive control 0.086 -0.255 -21.17 0.089 -0.254 -22.48 -30.864 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E01 mock treatment 0.333 -0.00803 -0.67 0.334 -0.00861 -0.76 -1.0113 -0.9977 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E02 mock treatment 0.347 0.00597 0.5 0.351 0.00839 0.74 0.8758 0.9805 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E03 compound treatment 0.322 -0.019 -1.58 0.331 -0.0116 -1.03 -1.845 -0.9784 1940499 CBMicro_029841 Cc1ccc(Cl)c(OCCCCN2CCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E04 compound treatment 0.321 -0.02 -1.66 0.337 -0.00561 -0.5 -1.5278 -0.8801 1940500 CBMicro_029842 Cc1[nH]c2ccc(Br)cc2c1CC(=O)NNS(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E05 compound treatment 0.346 0.00497 0.41 0.359 0.0164 1.45 1.3185 0.8734 1716747 CBMicro_029843 Cc1ccccc1NC(=O)CC2Sc3ccccc3NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E06 compound treatment 0.332 -0.00903 -0.75 0.341 -0.00161 -0.14 -0.6314 -0.827 1940501 CBMicro_029844 COc1ccc(Nc2nc(nc(C)c2C#N)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E07 compound treatment 0.323 -0.018 -1.5 0.342 -6.13E-4 -0.05 -1.097 -0.7323 1486841 CBMicro_029845 COc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)c3ccccc3C(=O)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E08 compound treatment 0.335 -0.00603 -0.5 0.339 -0.00361 -0.32 -0.5806 -0.9766 1237188 CBMicro_029846 COC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E09 compound treatment 0.333 -0.00803 -0.67 0.347 0.00439 0.39 -0.1967 -0.2548 1940502 CBMicro_029847 COC(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E10 compound treatment 0.335 -0.00603 -0.5 0.343 3.87E-4 0.03 -0.3299 -0.6571 1940503 CBMicro_029848 Cc1cc(C)n(CC(=O)n2nc(C)cc2C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E11 compound treatment 0.381 0.04 3.32 0.395 0.0524 4.64 5.629 0.9864 1940504 CBMicro_029849 CCCN(CCC)CN1C(=O)S/C(=C/c2ccc(SC)cc2)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E12 compound treatment 0.336 -0.00503 -0.42 0.345 0.00239 0.21 -0.1459 -0.3115 1940505 CBMicro_029850 CC1=CC(C)(C)N(C(=O)CN2C(=O)C3CCCCC3C2=O)c4cc(C)ccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E13 compound treatment 0.327 -0.014 -1.17 0.358 0.0154 1.36 0.1404 0.0783 1175850 CBMicro_029851 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCc2ccc(Cl)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E14 compound treatment 0.32 -0.021 -1.75 0.328 -0.0146 -1.3 -2.1504 -0.9892 1336299 CBMicro_029852 COc1ccccc1CC(=O)Nc2cc(Cl)ccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E15 compound treatment 0.409 0.068 5.64 0.416 0.0734 6.5 8.5887 0.9975 1940506 CBMicro_029853 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3ccccc3)cc(n2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E16 compound treatment 0.314 -0.027 -2.24 0.326 -0.0166 -1.47 -2.628 -0.9791 1940507 CBMicro_029854 Clc1cccc(OCCCN2CCCCC2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E17 compound treatment 0.333 -0.00803 -0.67 0.367 0.0244 2.16 1.0566 0.4672 1940508 CBMicro_029855 Cc1[nH]c2ccc(Br)cc2c1CC(=O)N/N=C/c3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E18 compound treatment 0.342 9.67E-4 0.08 0.339 -0.00361 -0.32 -0.1697 -0.514 1595704 CBMicro_029856 O=C(CC(c1ccccc1)c2ccccc2)NCC3CCCO3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E19 compound treatment 0.323 -0.018 -1.5 0.33 -0.0126 -1.12 -1.849 -0.9896 1164538 CBMicro_029857 Sc1nnc(c2ccco2)n1C3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E20 compound treatment 0.327 -0.014 -1.17 0.33 -0.0126 -1.12 -1.6142 -0.9998 1940509 CBMicro_029858 Cc1ccc(C)c(OCCCCN2CCCCC2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E21 compound treatment 0.344 0.00297 0.25 0.343 3.87E-4 0.03 0.1984 0.7979 1405093 CBMicro_029859 COc1cc(cc(OC)c1OC)C(=O)Nc2c(C)cccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E22 compound treatment 0.34 -0.00103 -0.09 0.349 0.00639 0.57 0.3396 0.5932 1183073 CBMicro_029860 CC(Sc1ccc(Cl)cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E23 positive control 0.082 -0.259 -21.5 0.085 -0.258 -22.83 -31.3494 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 E24 positive control 0.088 -0.253 -21.01 0.092 -0.251 -22.21 -30.5586 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F01 mock treatment 0.336 -0.00503 -0.42 0.337 -0.00561 -0.5 -0.6472 -0.9962 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F02 mock treatment 0.341 -3.33E-5 0.0 0.342 -6.13E-4 -0.05 -0.0404 -0.7422 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F03 compound treatment 0.376 0.035 2.9 0.385 0.0424 3.76 4.7089 0.9919 1940510 CBMicro_029861 Clc1cccc(CC2S/C(=N\c3ccccn3)/NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F04 compound treatment 0.38 0.039 3.23 0.366 0.0234 2.07 3.753 0.9768 1940511 CBMicro_029862 CCCOc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F05 compound treatment 0.294 -0.047 -3.9 0.336 -0.00661 -0.59 -3.1754 -0.8042 1940512 CBMicro_029863 Clc1ccc(Cl)c(c1)c2ccc(/C=C\C(=O)c3ccccc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F06 compound treatment 0.35 0.00897 0.74 0.344 0.00139 0.12 0.6133 0.8129 1940513 CBMicro_029864 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\NCC3(C)CC(O)CC(C)(C)C3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F07 compound treatment 0.339 -0.00203 -0.17 0.339 -0.00361 -0.32 -0.3458 -0.9553 1940514 CBMicro_029865 Clc1ccc(c2nc3cc(NC(=O)c4ccc(Br)o4)ccc3o2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F08 compound treatment 0.35 0.00897 0.74 0.375 0.0324 2.87 2.5559 0.862 1621850 CBMicro_029866 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F09 compound treatment 0.311 -0.03 -2.49 0.341 -0.00161 -0.14 -1.8641 -0.7464 1940515 CBMicro_029867 COc1ccc(/C=N/NC(=O)COc2ccccc2Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F10 compound treatment 0.337 -0.00403 -0.33 0.354 0.0114 1.01 0.4768 0.4484 1204082 CBMicro_029868 COc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccc(cc3)C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F11 compound treatment 0.373 0.032 2.65 0.411 0.0684 6.06 6.162 0.9314 1940516 CBMicro_029869 Cc1ccc(cc1C)N2C(=O)/C(=C/c3ccc(O)c(O)c3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F12 compound treatment 0.382 0.041 3.4 0.353 0.0104 0.92 3.0558 0.8673 1703928 CBMicro_029870 CCC(=O)Nc1ccc(cc1)c2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F13 compound treatment 0.344 0.00297 0.25 0.388 0.0454 4.02 3.0183 0.749 1940517 CBMicro_029871 Fc1ccc(NC(=O)CCCCCN2C(=O)c3ccccc3C2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F14 compound treatment 0.345 0.00397 0.33 0.375 0.0324 2.87 2.2624 0.7831 1940518 CBMicro_029872 COc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)n2CC(=C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F15 compound treatment 0.39 0.049 4.07 0.393 0.0504 4.47 6.032 0.9989 1940519 CBMicro_029873 Cc1[nH]nc(N2CCCCC2)c1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F16 compound treatment 0.341 -3.33E-5 0.0 0.35 0.00739 0.65 0.461 0.7041 1940520 CBMicro_029874 [O-][N+](=O)c1cccc(/C=C/C(=O)n2c(SCC#C)nc3ccccc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F17 compound treatment 0.352 0.011 0.91 0.36 0.0174 1.54 1.7333 0.9685 1940521 CBMicro_029875 CC(C)c1ccc(/C=C\2/SC(=O)N(C2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F18 compound treatment 0.352 0.011 0.91 0.35 0.00739 0.65 1.1067 0.9869 1940522 CBMicro_029876 Cc1c(Cl)cccc1NC(=O)C(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F19 compound treatment 0.422 0.081 6.72 0.462 0.119 10.58 12.2344 0.976 1940523 CBMicro_029877 CC(C)c1ccc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F20 compound treatment 0.342 9.67E-4 0.08 0.341 -0.00161 -0.14 -0.0443 -0.2704 1940524 CBMicro_029878 COc1ccccc1OCCOc2ccc(Br)cc2/C=N/n3cnnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F21 compound treatment 0.369 0.028 2.32 0.374 0.0314 2.78 3.6086 0.996 1594503 CBMicro_029879 Cc1cc(OCC(=O)Nc2cccc(Cl)c2C)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F22 compound treatment 0.338 -0.00303 -0.25 0.335 -0.00761 -0.67 -0.6551 -0.9097 1432576 CBMicro_029880 CCOCc1cnc(C)nc1NC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F23 positive control 0.084 -0.257 -21.34 0.087 -0.256 -22.65 -31.1067 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 F24 positive control 0.087 -0.254 -21.09 0.086 -0.257 -22.74 -30.9933 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G01 mock treatment 0.328 -0.013 -1.08 0.337 -0.00561 -0.5 -1.1168 -0.9378 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G02 mock treatment 0.336 -0.00503 -0.42 0.341 -0.00161 -0.14 -0.3965 -0.8979 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G03 compound treatment 0.324 -0.017 -1.41 0.329 -0.0136 -1.21 -1.853 -0.9969 1940525 CBMicro_029881 CCOc1ccc(cc1)N(CC(=O)NCCCN(C)C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G04 compound treatment 0.337 -0.00403 -0.33 0.342 -6.13E-4 -0.05 -0.2752 -0.8112 1940526 CBMicro_029882 CCOc1ccc(cc1)N(CC(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G05 compound treatment 0.334 -0.00703 -0.58 0.335 -0.00761 -0.67 -0.8899 -0.9974 1705053 CBMicro_029883 Cc1cc(Cl)c(OCCN2CCOCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G06 compound treatment 0.329 -0.012 -1.0 0.344 0.00139 0.12 -0.6195 -0.6155 1940527 CBMicro_029884 O=C/1C2CC(C\C1=C\c3cccs3)C(=O)/C(=C\c4cccs4)/C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G07 compound treatment 0.334 -0.00703 -0.58 0.349 0.00639 0.57 -0.0126 -0.0155 1281214 CBMicro_029885 Cc1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G08 compound treatment 0.413 0.072 5.97 0.439 0.0964 8.54 10.2648 0.9847 1701395 CBMicro_029886 Cc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)CCC4=O)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G09 compound treatment 0.31 -0.031 -2.58 0.382 0.0394 3.49 0.6464 0.149 1940528 CBMicro_029887 Clc1cccc(Cl)c1OCCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G10 compound treatment 0.351 0.00997 0.83 0.422 0.0794 7.04 5.5599 0.7849 1199347 CBMicro_029888 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)Nc3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G11 compound treatment 0.301 -0.04 -3.32 0.391 0.0484 4.29 0.6821 0.1257 1940529 CBMicro_029889 Cc1cc(Cl)cc(Cl)c1OCCCCN2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G12 compound treatment 0.325 -0.016 -1.33 0.385 0.0424 3.76 1.715 0.4303 1940530 CBMicro_029890 Cc1cc(Cl)cc(Cl)c1OCCNC(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G13 compound treatment 0.328 -0.013 -1.08 0.402 0.0594 5.26 2.9564 0.5502 1940531 CBMicro_029891 CCOc1ccc(cc1)N(CC(=O)Nc2cccc(c2)C(F)(F)F)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G14 compound treatment 0.339 -0.00203 -0.17 0.422 0.0794 7.04 4.8554 0.6899 1581244 CBMicro_029892 COc1ccccc1CC(=O)Nc2cccc(Cl)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G15 compound treatment 0.324 -0.017 -1.41 0.385 0.0424 3.76 1.6563 0.4126 1940532 CBMicro_029893 COCCCNC(=O)c1ccc(NC(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G16 compound treatment 0.411 0.07 5.81 0.462 0.119 10.58 11.5887 0.9601 1326077 CBMicro_029894 CCOC(=O)c1ccc(cc1)n2sc3c(-c4ccccc4NC3(C)C)c2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G17 compound treatment 0.333 -0.00803 -0.67 0.422 0.0794 7.04 4.5032 0.6372 1145063 CBMicro_029895 CCN(CC)c1ccc(cc1)C(=O)NCc2ccccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G18 compound treatment 0.329 -0.012 -1.0 0.377 0.0344 3.05 1.4485 0.4517 1940533 CBMicro_029896 CC(Sc1ccc(Cl)cc1)C(=O)Nc2cccc(c2)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G19 compound treatment 0.348 0.00697 0.58 0.379 0.0364 3.22 2.6892 0.8208 1302211 CBMicro_029897 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G20 compound treatment 0.412 0.071 5.89 0.419 0.0764 6.77 8.9528 0.9976 1940534 CBMicro_029898 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G21 compound treatment 0.341 -3.33E-5 0.0 0.344 0.00139 0.12 0.085 0.691 1940535 CBMicro_029899 COc1cccc2cc(C(=O)Nc3cccc(c3)C(=O)C)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G22 compound treatment 0.332 -0.00903 -0.75 0.335 -0.00761 -0.67 -1.0073 -0.9986 1065281 CBMicro_029900 CCOCc1ccc(O)c2ncccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G23 positive control 0.084 -0.257 -21.34 0.09 -0.253 -22.39 -30.9187 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 G24 positive control 0.09 -0.251 -20.84 0.102 -0.241 -21.32 -29.8145 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H01 mock treatment 0.332 -0.00903 -0.75 0.338 -0.00461 -0.41 -0.8194 -0.9593 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H02 mock treatment 0.348 0.00697 0.58 0.336 -0.00661 -0.59 -0.0054 -0.0066 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H03 compound treatment 0.48 0.139 11.54 0.483 0.14 12.44 16.9552 0.9993 1940536 CBMicro_029901 CS(=O)(=O)N1CCN(CC1)c2ccc([N+](=O)[O-])c(c2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H04 compound treatment 0.371 0.03 2.49 0.384 0.0414 3.67 4.3527 0.9821 1940537 CBMicro_029902 [O-][N+](=O)c1cccc(/C=C\2/N=C(\OC2=O)/C=C/c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H05 compound treatment 0.33 -0.011 -0.92 0.337 -0.00561 -0.5 -0.9994 -0.9588 1940538 CBMicro_029903 CCCN(CCC)C1=CC(=O)C(=CC1=O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H06 compound treatment 0.33 -0.011 -0.92 0.341 -0.00161 -0.14 -0.7488 -0.8077 1940539 CBMicro_029904 CN1C(=O)C(=CNCC2(C)CC(O)CC(C)(C)C2)C(=O)N(C)C1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H07 compound treatment 0.353 0.012 0.99 0.365 0.0224 1.98 2.1054 0.9489 1288261 CBMicro_029905 Cc1ccc(cc1NC(=O)c2ccc(Br)o2)c3nc4cc(Cl)ccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H08 compound treatment 0.327 -0.014 -1.17 0.335 -0.00761 -0.67 -1.3009 -0.9663 1738131 CBMicro_029906 OC(=O)c1cc(NS(=O)(=O)c2ccccc2)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H09 compound treatment 0.311 -0.03 -2.49 0.342 -6.13E-4 -0.05 -1.8015 -0.7223 1409373 CBMicro_029907 CCOC(=O)c1c(C)c(sc1N)C(=O)OC(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H10 compound treatment 0.323 -0.018 -1.5 0.331 -0.0116 -1.03 -1.7863 -0.9833 1178077 CBMicro_029908 COc1cc(CN2CCN(Cc3ccc(Cl)cc3)CC2)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H11 compound treatment 0.312 -0.029 -2.41 0.329 -0.0136 -1.21 -2.5574 -0.9488 1713267 CBMicro_029909 CCOc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H12 compound treatment 0.355 0.014 1.16 0.347 0.00439 0.39 1.0948 0.8952 1940540 CBMicro_029910 COc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)n2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H13 compound treatment 0.354 0.013 1.08 0.37 0.0274 2.43 2.4774 0.9331 1543149 CBMicro_029911 CCOc1cccc(c1)C(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H14 compound treatment 0.334 -0.00703 -0.58 0.336 -0.00661 -0.59 -0.8273 -1.0 1940541 CBMicro_029912 OC(=O)CSc1nnc(c2ccc(Cl)cc2Cl)n1c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H15 compound treatment 0.33 -0.011 -0.92 0.339 -0.00361 -0.32 -0.8741 -0.9008 1306329 CBMicro_029913 CN(C)c1cccc(c1)C(=O)Nc2ccccc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H16 compound treatment 0.387 0.046 3.82 0.376 0.0334 2.96 4.7906 0.9921 1940542 CBMicro_029914 COc1ccc(/C=C/2\CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H17 compound treatment 0.335 -0.00603 -0.5 0.354 0.0114 1.01 0.3594 0.319 1158793 CBMicro_029915 COC(=O)c1ccc(NC(=S)NC(=O)CCN2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H18 compound treatment 0.344 0.00297 0.25 0.347 0.00439 0.39 0.4491 0.9757 1571614 CBMicro_029916 COc1ccc(CNC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H19 compound treatment 0.333 -0.00803 -0.67 0.333 -0.00961 -0.85 -1.074 -0.9927 1427331 CBMicro_029917 OC(=O)C1CCCCC1C(=O)Nc2nc(cs2)c3ccc(Cl)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H20 compound treatment 0.418 0.077 6.39 0.396 0.0534 4.73 7.8637 0.9891 1940543 CBMicro_029918 CC(C)c1ccc(C)cc1OCCOc2ccc(Cl)cc2/C=N/n3cnnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H21 compound treatment 0.337 -0.00403 -0.33 0.341 -0.00161 -0.14 -0.3378 -0.9279 1940544 CBMicro_029919 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OC(=O)c3ccccc3)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H22 compound treatment 0.341 -3.33E-5 0.0 0.339 -0.00361 -0.32 -0.2284 -0.7132 1698336 CBMicro_029920 Cc1ccccc1N2C(=O)CC(=O)N(C2=S)c3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H23 positive control 0.087 -0.254 -21.09 0.088 -0.255 -22.56 -30.8679 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 H24 positive control 0.091 -0.25 -20.76 0.086 -0.257 -22.74 -30.7585 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I01 mock treatment 0.342 9.67E-4 0.08 0.347 0.00439 0.39 0.3317 0.8355 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I02 mock treatment 0.347 0.00597 0.5 0.35 0.00739 0.65 0.8132 0.9905 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I03 compound treatment 0.345 0.00397 0.33 0.349 0.00639 0.57 0.6331 0.9668 1940545 CBMicro_029921 O[C@@H]1CCCC[C@H]1NC(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I04 compound treatment 0.329 -0.012 -1.0 0.334 -0.00861 -0.76 -1.2461 -0.9912 1940546 CBMicro_029922 CC(=O)c1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I05 compound treatment 0.352 0.011 0.91 0.359 0.0164 1.45 1.6707 0.9747 1499714 CBMicro_029923 Cc1ccc(Cl)cc1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I06 compound treatment 0.34 -0.00103 -0.09 0.346 0.00339 0.3 0.1516 0.4856 1940547 CBMicro_029924 COc1ccccc1CC(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I07 compound treatment 0.352 0.011 0.91 0.355 0.0124 1.1 1.42 0.9957 1415727 CBMicro_029925 CC(C)N(C(C)C)C(=O)c1ccc(cc1)C(=O)Nc2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I08 compound treatment 0.359 0.018 1.49 0.353 0.0104 0.92 1.7056 0.9731 1940548 CBMicro_029926 COc1ccc(NC(=O)Cc2ccc(OC)c(OC)c2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I09 compound treatment 0.335 -0.00603 -0.5 0.35 0.00739 0.65 0.1087 0.1319 1612284 CBMicro_029927 Clc1cccc(Cl)c1OCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I10 compound treatment 0.342 9.67E-4 0.08 0.345 0.00239 0.21 0.2063 0.9119 1344291 CBMicro_029928 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I11 compound treatment 0.435 0.094 7.8 0.452 0.109 9.69 12.3709 0.9942 1940549 CBMicro_029929 Cc1nn(c2OC(=C(C#N)C(c12)c3c(O)ccc4ccccc34)N)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I12 compound treatment 0.336 -0.00503 -0.42 0.343 3.87E-4 0.03 -0.2712 -0.6469 1261580 CBMicro_029930 Clc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I13 compound treatment 0.339 -0.00203 -0.17 0.356 0.0134 1.19 0.7195 0.6004 1643570 CBMicro_029931 COC(=O)c1ccccc1NC(=O)Cc2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I14 compound treatment 0.326 -0.015 -1.25 0.342 -6.13E-4 -0.05 -0.9209 -0.7372 1940550 CBMicro_029932 OC(C(=O)NNc1ccc(F)cc1)(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I15 compound treatment 0.342 9.67E-4 0.08 0.329 -0.0136 -1.21 -0.7963 -0.6586 1940551 CBMicro_029933 Fc1ccc(/C=C\2/SC(=O)N(CNc3ccc(I)cc3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I16 compound treatment 0.332 -0.00903 -0.75 0.339 -0.00361 -0.32 -0.7567 -0.928 1940552 CBMicro_029934 COc1ccc(cc1NS(=O)(=O)c2ccc(F)cc2)C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I17 compound treatment 0.333 -0.00803 -0.67 0.346 0.00339 0.3 -0.2593 -0.3546 1940553 CBMicro_029935 Cc1ccc(cc1)c2nnc(S)n2c3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I18 compound treatment 0.336 -0.00503 -0.42 0.345 0.00239 0.21 -0.1459 -0.3115 1166068 CBMicro_029936 CN(C)c1cccc(c1)C(=O)NCCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I19 compound treatment 0.347 0.00597 0.5 0.346 0.00339 0.3 0.5625 0.9712 1185067 CBMicro_029937 COc1ccccc1CC(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I20 compound treatment 0.342 9.67E-4 0.08 0.346 0.00339 0.3 0.269 0.8657 1726129 CBMicro_029938 CC(Nc1cc(=O)n(C)c(=O)n1C)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I21 compound treatment 0.349 0.00797 0.66 0.362 0.0194 1.72 1.6826 0.9139 1940554 CBMicro_029939 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I22 compound treatment 0.346 0.00497 0.41 0.331 -0.0116 -1.03 -0.4362 -0.3934 1529987 CBMicro_029940 CCOc1ccc(cc1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I23 positive control 0.124 -0.217 -18.02 0.088 -0.255 -22.56 -28.6959 -0.9938 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 I24 positive control 0.091 -0.25 -20.76 0.091 -0.252 -22.3 -30.4451 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J01 mock treatment 0.319 -0.022 -1.83 0.333 -0.00961 -0.85 -1.8958 -0.9395 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J02 mock treatment 0.354 0.013 1.08 0.355 0.0124 1.1 1.5374 1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J03 compound treatment 0.323 -0.018 -1.5 0.333 -0.00961 -0.85 -1.661 -0.9643 1243954 CBMicro_029941 COc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4c(=O)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J04 compound treatment 0.336 -0.00503 -0.42 0.341 -0.00161 -0.14 -0.3965 -0.8979 1940555 CBMicro_029942 Brc1ccc(o1)C(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J05 compound treatment 0.335 -0.00603 -0.5 0.361 0.0184 1.63 0.7981 0.4681 1587498 CBMicro_029943 C=CCc1cccc2cc(C(=O)NCc3ccccc3)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J06 compound treatment 0.339 -0.00203 -0.17 0.35 0.00739 0.65 0.3436 0.5082 1940556 CBMicro_029944 CC1(C)CC(O)CC(C)(CN/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J07 compound treatment 0.328 -0.013 -1.08 0.346 0.00339 0.3 -0.5528 -0.4923 1940557 CBMicro_029945 [O-][N+](=O)c1ccc(Oc2ccc3c(=O)[nH][nH]c(=O)c3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J08 compound treatment 0.357 0.016 1.33 0.368 0.0254 2.25 2.5282 0.9682 1940558 CBMicro_029946 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(OC)cc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J09 compound treatment 0.348 0.00697 0.58 0.338 -0.00461 -0.41 0.1199 0.1693 1428896 CBMicro_029947 Brc1cccc(c1)C(=O)Nc2c[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J10 compound treatment 0.332 -0.00903 -0.75 0.338 -0.00461 -0.41 -0.8194 -0.9593 1940559 CBMicro_029948 CC(=O)c1ccc(NC(=O)CSc2ncn[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J11 compound treatment 0.335 -0.00603 -0.5 0.344 0.00139 0.12 -0.2673 -0.5182 1940560 CBMicro_029949 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)n4nnc5ccccc45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J12 compound treatment 0.345 0.00397 0.33 0.345 0.00239 0.21 0.3824 0.9771 1940561 CBMicro_029950 COc1ccccc1N2CCN(CC2)/N=C\c3c(C)nn(c3C)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J13 compound treatment 0.346 0.00497 0.41 0.354 0.0114 1.01 1.0051 0.922 1940562 CBMicro_029951 COc1cc(/C=N\NC(=O)c2cccc3ccccc23)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J14 compound treatment 0.32 -0.021 -1.75 0.329 -0.0136 -1.21 -2.0878 -0.9837 1457797 CBMicro_029952 Cc1ccc(cc1)S(=O)(=O)c2cc(O)ccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J15 compound treatment 0.341 -3.33E-5 0.0 0.344 0.00139 0.12 0.085 0.691 1780842 CBMicro_029953 Cc1cc(ccc1[N+](=O)[O-])c2nc3ccc(Br)cc3c(=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J16 compound treatment 0.464 0.123 10.21 0.432 0.0894 7.92 12.82 0.9921 1940563 CBMicro_029954 COc1cc(cc(OC)c1OC)C(=O)N/C(=C/c2ccc(cc2)N(C)C)/C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J17 compound treatment 0.337 -0.00403 -0.33 0.348 0.00539 0.48 0.1008 0.1729 1520684 CBMicro_029955 CCOc1ccccc1NC(=O)C(C)N2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J18 compound treatment 0.338 -0.00303 -0.25 0.343 3.87E-4 0.03 -0.1538 -0.6052 1665748 CBMicro_029956 OCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J19 compound treatment 0.343 0.00197 0.16 0.349 0.00639 0.57 0.5157 0.8754 1263072 CBMicro_029957 COc1ccc(CCNC(=O)C2CCCCC2C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J20 compound treatment 0.341 -3.33E-5 0.0 0.356 0.0134 1.19 0.8369 0.7055 1514187 CBMicro_029958 COc1ccc(OC)c(NC(=O)COc2c(C)cccc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J21 compound treatment 0.47 0.129 10.71 0.473 0.13 11.56 15.7415 0.9993 1940564 CBMicro_029959 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/n3cnnc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J22 compound treatment 0.356 0.015 1.24 0.348 0.00539 0.48 1.2162 0.9137 1940565 CBMicro_029960 COc1ccc2/C(=N\OC(=O)c3ccc(OC)c(OC)c3)/CCc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J23 positive control 0.086 -0.255 -21.17 0.09 -0.253 -22.39 -30.8013 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 J24 positive control 0.09 -0.251 -20.84 0.097 -0.246 -21.77 -30.1278 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K01 mock treatment 0.334 -0.00703 -0.58 0.353 0.0104 0.92 0.238 0.2184 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K02 mock treatment 0.34 -0.00103 -0.09 0.342 -6.13E-4 -0.05 -0.0991 -0.9757 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K03 compound treatment 0.345 0.00397 0.33 0.343 3.87E-4 0.03 0.2571 0.7766 1050413 CBMicro_029961 Cc1ccc(cc1)N2CCN(CC2)C(=S)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K04 compound treatment 0.328 -0.013 -1.08 0.334 -0.00861 -0.76 -1.3048 -0.9854 1940566 CBMicro_029962 CCN(CC)CCOc1ccc(Cl)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K05 compound treatment 0.337 -0.00403 -0.33 0.343 3.87E-4 0.03 -0.2125 -0.6314 1119247 CBMicro_029963 O=C1N(C(=O)c2ncccc12)c3cccc(c3)c4nc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K06 compound treatment 0.316 -0.025 -2.08 0.313 -0.0296 -2.62 -3.3252 -0.9933 1940567 CBMicro_029964 CC(C)(C)NCCCCOc1ccc2ccccc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K07 compound treatment 0.338 -0.00303 -0.25 0.329 -0.0136 -1.21 -1.0311 -0.8367 1239509 CBMicro_029965 CN(C(=O)c1ccc(cc1)C(=O)N(C)c2ccc(O)cc2)c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K08 compound treatment 0.43 0.089 7.39 0.421 0.0784 6.95 10.1348 0.9995 1940568 CBMicro_029966 COC(=O)C/1=C(C)N(CC=C)C(=O)\C1=C/c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K09 compound treatment 0.326 -0.015 -1.25 0.335 -0.00761 -0.67 -1.3596 -0.9583 1388485 CBMicro_029967 COc1ccccc1CC(=O)NC2CCCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K10 compound treatment 0.348 0.00697 0.58 0.334 -0.00861 -0.76 -0.1308 -0.1365 1593957 CBMicro_029968 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K11 compound treatment 0.421 0.08 6.64 0.428 0.0854 7.57 10.0451 0.9979 1940569 CBMicro_029969 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc([N+](=O)[O-])c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K12 compound treatment 0.325 -0.016 -1.33 0.326 -0.0166 -1.47 -1.9823 -0.9987 1659889 CBMicro_029970 CCOc1cc(C=O)ccc1OCc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K13 compound treatment 0.313 -0.028 -2.33 0.325 -0.0176 -1.56 -2.7494 -0.9811 1940570 CBMicro_029971 COc1nc(c[n+](C)n1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K14 compound treatment 0.328 -0.013 -1.08 0.337 -0.00561 -0.5 -1.1168 -0.9378 1466608 CBMicro_029972 Cc1cccc(NC(=O)c2c(Cl)cccc2Cl)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K15 compound treatment 0.344 0.00297 0.25 0.342 -6.13E-4 -0.05 0.1357 0.5382 1376052 CBMicro_029973 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCC2CCCO2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K16 compound treatment 0.356 0.015 1.24 0.357 0.0144 1.28 1.7802 0.9999 1940571 CBMicro_029974 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2cc(Cl)ccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K17 compound treatment 0.352 0.011 0.91 0.359 0.0164 1.45 1.6707 0.9747 1940572 CBMicro_029975 N1C=NN=C(C1c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K18 compound treatment 0.33 -0.011 -0.92 0.341 -0.00161 -0.14 -0.7488 -0.8077 1940573 CBMicro_029976 Clc1cccc(Cl)c1OCCCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K19 compound treatment 0.339 -0.00203 -0.17 0.344 0.00139 0.12 -0.0324 -0.1554 1940574 CBMicro_029977 COCCCNC(=O)Cc1ccc(OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K20 compound treatment 0.352 0.011 0.91 0.352 0.00939 0.83 1.232 0.999 1940575 CBMicro_029978 COc1cc(NC(=O)CCCOc2ccc(Cl)cc2Cl)c3ncccc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K21 compound treatment 0.404 0.063 5.23 0.408 0.0654 5.79 7.7938 0.9987 1940576 CBMicro_029979 CC(=O)Nc1ccc(Nc2cc(Cl)c(cc2[N+](=O)[O-])C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K22 compound treatment 0.326 -0.015 -1.25 0.352 0.00939 0.83 -0.2943 -0.1962 1334604 CBMicro_029980 COc1ccccc1CC(=O)Nc2ccc(C)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K23 positive control 0.087 -0.254 -21.09 0.088 -0.255 -22.56 -30.8679 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 K24 positive control 0.094 -0.247 -20.51 0.096 -0.247 -21.86 -29.9557 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L01 mock treatment 0.338 -0.00303 -0.25 0.342 -6.13E-4 -0.05 -0.2165 -0.8403 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L02 mock treatment 0.346 0.00497 0.41 0.343 3.87E-4 0.03 0.3158 0.7633 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L03 compound treatment 0.338 -0.00303 -0.25 0.337 -0.00561 -0.5 -0.5298 -0.9502 1455389 CBMicro_029981 OC(=O)c1cc(O)ccc1NC(=O)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L04 compound treatment 0.333 -0.00803 -0.67 0.334 -0.00861 -0.76 -1.0113 -0.9977 1940577 CBMicro_029982 CCOC(=O)c1c(NC(=O)CC2SC(=N)NC2=O)sc3CCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L05 compound treatment 0.326 -0.015 -1.25 0.336 -0.00661 -0.59 -1.2969 -0.9406 1940578 CBMicro_029983 CCN(CC)CCCOc1ccccc1CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L06 compound treatment 0.333 -0.00803 -0.67 0.339 -0.00361 -0.32 -0.698 -0.9435 1940579 CBMicro_029984 CC(=O)Nc1ccc(cc1)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L07 compound treatment 0.361 0.02 1.66 0.362 0.0194 1.72 2.387 0.9998 1940580 CBMicro_029985 COC(=O)c1ccc(/C=N/NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L08 compound treatment 0.361 0.02 1.66 0.362 0.0194 1.72 2.387 0.9998 1208470 CBMicro_029986 CCOC(=O)C1=C(C)NC(=C(C1c2ccc(C)cc2)C(=O)OCC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L09 compound treatment 0.358 0.017 1.41 0.361 0.0184 1.63 2.1482 0.9974 1368023 CBMicro_029987 CC(C)(C)c1cc(CCC(=O)NN2C(=O)CSC2=S)cc(c1O)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L10 compound treatment 0.347 0.00597 0.5 0.349 0.00639 0.57 0.7505 0.9978 1940581 CBMicro_029988 Cc1ccc(cc1)c2cc3nc(C)cc(C)n3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L11 compound treatment 0.346 0.00497 0.41 0.33 -0.0126 -1.12 -0.4988 -0.4187 1735609 CBMicro_029989 COc1cc(cc(OC)c1OC)C(=O)Nc2ncc3C(=O)CC(C)(C)Cc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L12 compound treatment 0.329 -0.012 -1.0 0.332 -0.0106 -0.94 -1.3715 -0.9995 1940582 CBMicro_029990 Oc1c(CC=C)cccc1/C=N\N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L13 compound treatment 0.337 -0.00403 -0.33 0.331 -0.0116 -1.03 -0.9645 -0.8912 1120967 CBMicro_029991 Clc1ccc(cc1)S(=O)(=O)NCC(N2CCCCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L14 compound treatment 0.336 -0.00503 -0.42 0.327 -0.0156 -1.38 -1.2739 -0.8813 1940583 CBMicro_029992 Cc1nn(c(C)c1/C=N/O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L15 compound treatment 0.335 -0.00603 -0.5 0.338 -0.00461 -0.41 -0.6432 -0.9949 1940584 CBMicro_029993 Cc1ccc(/C=C\2/SC(=O)N(CNc3ccc(Br)cc3C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L16 compound treatment 0.363 0.022 1.82 0.38 0.0374 3.31 3.6324 0.9604 1940585 CBMicro_029994 COc1ccc(/C=C/C(=O)c2ccc(cc2)[N+](=O)[O-])s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L17 compound treatment 0.328 -0.013 -1.08 0.336 -0.00661 -0.59 -1.1795 -0.9585 1940586 CBMicro_029995 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OC(=O)c3cc(F)c(F)cc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L18 compound treatment 0.333 -0.00803 -0.67 0.34 -0.00261 -0.23 -0.6353 -0.8999 1940587 CBMicro_029996 COC(=O)c1ccc(N/C=C\2/C(=O)NC(=O)N(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L19 compound treatment 0.342 9.67E-4 0.08 0.344 0.00139 0.12 0.1437 0.9786 1216550 CBMicro_029997 CC(Oc1ccc(Cl)cc1C)C(=O)NCCC2=CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L20 compound treatment 0.377 0.036 2.99 0.378 0.0354 3.14 4.3289 0.9997 1126534 CBMicro_029998 CC(C)OC(=O)c1ccc(NC(=O)COc2cc(Cl)ccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L21 compound treatment 0.38 0.039 3.23 0.376 0.0334 2.96 4.3797 0.999 1940588 CBMicro_029999 [O-][N+](=O)c1ccccc1c2ccc(/C=N/n3cnnc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L22 compound treatment 0.354 0.013 1.08 0.362 0.0194 1.72 1.9761 0.9746 1940589 CBMicro_030000 COC(=O)C1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L23 positive control 0.087 -0.254 -21.09 0.089 -0.254 -22.48 -30.8053 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 L24 positive control 0.091 -0.25 -20.76 0.096 -0.247 -21.86 -30.1318 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M01 mock treatment 0.337 -0.00403 -0.33 0.342 -6.13E-4 -0.05 -0.2752 -0.8112 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M02 mock treatment 0.338 -0.00303 -0.25 0.34 -0.00261 -0.23 -0.3418 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M03 compound treatment 0.356 0.015 1.24 0.347 0.00439 0.39 1.1535 0.886 1940590 CBMicro_030001 COC(=O)C/1=C(C)N(C)C(=O)\C1=C/c2ccc(OCC=C)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M04 compound treatment 0.333 -0.00803 -0.67 0.336 -0.00661 -0.59 -0.886 -0.9979 1940591 CBMicro_030002 CCN(CC)CCOc1ccccc1CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M05 compound treatment 0.673 0.332 27.56 0.687 0.344 30.52 41.0686 0.9987 1940592 CBMicro_030003 OC(=O)CN1C(=O)/C(=C/c2ccc(o2)c3ccccc3[N+](=O)[O-])/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M06 compound treatment 0.333 -0.00803 -0.67 0.335 -0.00761 -0.67 -0.9486 -1.0 1781489 CBMicro_030004 [O-][N+](=O)c1cccc(c1)N(CC(=O)N2CCc3ccccc3C2)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M07 compound treatment 0.329 -0.012 -1.0 0.33 -0.0126 -1.12 -1.4968 -0.9984 1400870 CBMicro_030005 O=S(=O)(Nc1ccc(cc1)S(=O)(=O)N2CCCCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M08 compound treatment 0.341 -3.33E-5 0.0 0.339 -0.00361 -0.32 -0.2284 -0.7132 1540783 CBMicro_030006 COC(=O)c1ccc(cc1)N(Cc2ccc(Cl)cc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M09 compound treatment 0.349 0.00797 0.66 0.345 0.00239 0.21 0.6173 0.8889 1940593 CBMicro_030007 Cc1ccc(NC(=O)/C(=C\c2cc(Br)cc(Br)c2O)/C#N)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M10 compound treatment 0.349 0.00797 0.66 0.353 0.0104 0.92 1.1186 0.9868 1940594 CBMicro_030008 COc1ccc2oc(=O)c(cc2c1)C(=O)Nc3cccc(c3)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M11 compound treatment 0.333 -0.00803 -0.67 0.329 -0.0136 -1.21 -1.3246 -0.9609 1282039 CBMicro_030009 Clc1ccc(Cl)c(c1)C(=O)NCCN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M12 compound treatment 0.346 0.00497 0.41 0.339 -0.00361 -0.32 0.0652 0.1248 1326760 CBMicro_030010 Cc1c(NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M13 compound treatment 0.594 0.253 21.0 0.606 0.263 23.34 31.3552 0.9986 1940595 CBMicro_030011 CC(C)c1ccc(/C=C\2/SC(=S)N(CN3CCOCC3)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M14 compound treatment 0.382 0.041 3.4 0.413 0.0704 6.24 6.8157 0.9593 1940596 CBMicro_030012 COc1ccc(cc1)C2CC(=NN2c3ccccc3OC)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M15 compound treatment 0.328 -0.013 -1.08 0.336 -0.00661 -0.59 -1.1795 -0.9585 1940597 CBMicro_030013 COCCCNC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M16 compound treatment 0.334 -0.00703 -0.58 0.338 -0.00461 -0.41 -0.7019 -0.9848 1478298 CBMicro_030014 Cc1cc(C)c(OCCN2CCOCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M17 compound treatment 0.422 0.081 6.72 0.448 0.105 9.34 11.3571 0.987 1940598 CBMicro_030015 COc1cc(/C=C\2/SC(=S)N(C2=O)c3cccc(Cl)c3)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M18 compound treatment 0.343 0.00197 0.16 0.352 0.00939 0.83 0.7037 0.83 1674084 CBMicro_030016 Cn1c(=O)cc(Nc2ccc(Cl)cc2)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M19 compound treatment 0.34 -0.00103 -0.09 0.339 -0.00361 -0.32 -0.2871 -0.866 1654027 CBMicro_030017 CCN(CC)c1ccc(cc1)C(=O)Nc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M20 compound treatment 0.337 -0.00403 -0.33 0.336 -0.00661 -0.59 -0.6512 -0.9647 1781761 CBMicro_030018 COc1ccc(N(CC(=O)N2CCCCC2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M21 compound treatment 0.347 0.00597 0.5 0.343 3.87E-4 0.03 0.3745 0.7543 1194788 CBMicro_030019 Cc1ccc(Cl)cc1N(Cc2ccc(cc2)C(=O)N3CCCC3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M22 compound treatment 0.344 0.00297 0.25 0.345 0.00239 0.21 0.3237 0.9971 1485137 CBMicro_030020 COc1ccc(OC)c(NC(=O)c2ccc(cc2C(=O)O)C(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M23 positive control 0.086 -0.255 -21.17 0.091 -0.252 -22.3 -30.7386 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 M24 positive control 0.092 -0.249 -20.67 0.097 -0.246 -21.77 -30.0104 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N01 mock treatment 0.344 0.00297 0.25 0.344 0.00139 0.12 0.2611 0.9485 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N02 mock treatment 0.344 0.00297 0.25 0.348 0.00539 0.48 0.5117 0.9526 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N03 compound treatment 0.288 -0.053 -4.4 0.305 -0.0376 -3.33 -5.4702 -0.9906 1940599 CBMicro_030021 COc1ccc(/N=C(/Sc2nc3ccccc3s2)\c4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N04 compound treatment 0.339 -0.00203 -0.17 0.342 -6.13E-4 -0.05 -0.1578 -0.8897 1864219 CBMicro_030022 NC(=O)c1ccc(NC(=O)CCN2C(=O)c3cccc([N+](=O)[O-])c3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N05 compound treatment 0.363 0.022 1.82 0.373 0.0304 2.69 3.1937 0.982 1940600 CBMicro_030023 Clc1ccc(cc1)c2ccc(/C=C\c3nc4ccccc4o3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N06 compound treatment 0.467 0.126 10.46 0.46 0.117 10.4 14.7507 1.0 1940601 CBMicro_030024 COc1ccccc1N2CCN(CC2)/N=C\3/C(=O)Nc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N07 compound treatment 0.364 0.023 1.91 0.358 0.0154 1.36 2.3125 0.9865 1940602 CBMicro_030025 CC1=C(C(NC(=S)N1)c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N08 compound treatment 0.341 -3.33E-5 0.0 0.34 -0.00261 -0.23 -0.1657 -0.7155 1289145 CBMicro_030026 O=C(CN1C(=O)c2ccccc2C1=O)Nc3cccc4ncccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N09 compound treatment 0.782 0.441 36.61 0.736 0.393 34.86 50.5378 0.9997 1940603 CBMicro_030027 CCCOc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N10 compound treatment 0.333 -0.00803 -0.67 0.339 -0.00361 -0.32 -0.698 -0.9435 1940604 CBMicro_030028 CC(C)N1CCN(Cc2ccc(Br)cc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N11 compound treatment 0.344 0.00297 0.25 0.338 -0.00461 -0.41 -0.1149 -0.2408 1052648 CBMicro_030029 Oc1ccc2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N12 compound treatment 0.36 0.019 1.57 0.37 0.0274 2.43 2.8296 0.9781 1740239 CBMicro_030030 O=C(Cn1c(nc2ccccc12)C(=O)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N13 compound treatment 0.345 0.00397 0.33 0.342 -6.13E-4 -0.05 0.1944 0.5826 1940605 CBMicro_030031 O=C1NC(=O)C(=CNCc2ccccc2)C(=O)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N14 compound treatment 0.356 0.015 1.24 0.354 0.0114 1.01 1.5922 0.9947 1781835 CBMicro_030032 Cc1ncc([N+](=O)[O-])n1CCOC(=O)Nc2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N15 compound treatment 0.326 -0.015 -1.25 0.329 -0.0136 -1.21 -1.7356 -0.9999 1940606 CBMicro_030033 CC(C)(C)NCCOc1ccc(Cl)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N16 compound treatment 0.343 0.00197 0.16 0.348 0.00539 0.48 0.453 0.8979 1940607 CBMicro_030034 CC12CCC3C(CC=C4CC(O)CCC34C)C2C/C(=C\c5ccc(cc5)[N+](=O)[O-])/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N17 compound treatment 0.345 0.00397 0.33 0.355 0.0124 1.1 1.0091 0.8805 1940608 CBMicro_030035 CCOC(=O)c1sc2ncn(/N=C/c3ccc(O)cc3)c(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N18 compound treatment 0.363 0.022 1.82 0.369 0.0264 2.34 2.9431 0.9924 1270506 CBMicro_030036 Cc1cccc(NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)c3ccccc3)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N19 compound treatment 0.339 -0.00203 -0.17 0.36 0.0174 1.54 0.9702 0.6259 1424439 CBMicro_030037 COc1cc(OC)cc(c1)C(=O)NCCC2=CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N20 compound treatment 0.35 0.00897 0.74 0.356 0.0134 1.19 1.3653 0.9748 1323305 CBMicro_030038 NS(=O)(=O)c1ccc(NC(=O)Cc2cccc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N21 compound treatment 0.356 0.015 1.24 0.358 0.0154 1.36 1.8428 0.9989 1483810 CBMicro_030039 Clc1cccc(c1)c2nnc(o2)c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N22 compound treatment 0.343 0.00197 0.16 0.345 0.00239 0.21 0.265 0.9918 1940609 CBMicro_030040 COc1ccc2/C(=N\OC(=O)c3ccc(OC)c(c3)[N+](=O)[O-])/CCc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N23 positive control 0.088 -0.253 -21.01 0.091 -0.252 -22.3 -30.6212 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 N24 positive control 0.093 -0.248 -20.59 0.094 -0.249 -22.03 -30.1397 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O01 mock treatment 0.342 9.67E-4 0.08 0.347 0.00439 0.39 0.3317 0.8355 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O02 mock treatment 0.343 0.00197 0.16 0.346 0.00339 0.3 0.3277 0.959 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O03 compound treatment 0.335 -0.00603 -0.5 0.338 -0.00461 -0.41 -0.6432 -0.9949 1940610 CBMicro_030041 CC(C)(C)NCCOc1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O04 compound treatment 0.341 -3.33E-5 0.0 0.346 0.00339 0.3 0.2103 0.7006 1488454 CBMicro_030042 COc1ccc(CC(=O)Nc2ccc(C)c(C)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O05 compound treatment 0.339 -0.00203 -0.17 0.353 0.0104 0.92 0.5315 0.568 1940611 CBMicro_030043 [O-][N+](=O)c1ccc(/C=C/C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O06 compound treatment 0.186 -0.155 -12.87 0.203 -0.14 -12.37 -17.8498 -0.9998 1940612 CBMicro_030044 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(Br)o3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O07 compound treatment 0.349 0.00797 0.66 0.338 -0.00461 -0.41 0.1786 0.2297 1940613 CBMicro_030045 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)N[C@H]3C[C@@H]4CC[C@H]3C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O08 compound treatment 0.412 0.071 5.89 0.44 0.0974 8.63 10.2687 0.9827 1940614 CBMicro_030046 Oc1ccc(NC(=O)/C(=C\c2cccc3ccccc23)/C#N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O09 compound treatment 0.343 0.00197 0.16 0.346 0.00339 0.3 0.3277 0.959 1940615 CBMicro_030047 COc1ccc(OCCOCCOc2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O10 compound treatment 0.344 0.00297 0.25 0.341 -0.00161 -0.14 0.0731 0.2566 1274037 CBMicro_030048 CC(=O)Nc1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O11 compound treatment 0.357 0.016 1.33 0.365 0.0224 1.98 2.3402 0.9808 1633754 CBMicro_030049 COc1ccccc1NC(=O)c2ccc(cc2)C(=O)c3c(C)cc(C)cc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O12 compound treatment 0.355 0.014 1.16 0.351 0.00839 0.74 1.3455 0.9769 1699524 CBMicro_030050 CN(C)c1cccc(c1)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O13 compound treatment 0.363 0.022 1.82 0.358 0.0154 1.36 2.2537 0.9897 1940616 CBMicro_030051 Cc1ccccc1C(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O14 compound treatment 0.37 0.029 2.4 0.364 0.0214 1.9 3.0407 0.9931 1940617 CBMicro_030052 COc1cc(/C=C/2\SC(=O)NC2=O)ccc1OCC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O15 compound treatment 0.37 0.029 2.4 0.373 0.0304 2.69 3.6046 0.9984 1494441 CBMicro_030053 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc2ccc(F)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O16 compound treatment 0.356 0.015 1.24 0.363 0.0204 1.81 2.1562 0.9833 1619979 CBMicro_030054 CCN(CC)c1ccc(cc1)C(=O)Nc2ccc(F)cc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O17 compound treatment 0.349 0.00797 0.66 0.352 0.00939 0.83 1.0559 0.9935 1940618 CBMicro_030055 CCOC(=O)C1=C(C)N(C(=S)NC1c2ccc(Br)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O18 compound treatment 0.335 -0.00603 -0.5 0.344 0.00139 0.12 -0.2673 -0.5182 1940619 CBMicro_030056 COc1cc2CC(=O)OC(c2cc1OC)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O19 compound treatment 0.368 0.027 2.24 0.371 0.0284 2.52 3.3619 0.9983 1940620 CBMicro_030057 O=C(Nc1cccc(c1)c2nnc(o2)c3ccccc3)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O20 compound treatment 0.483 0.142 11.79 0.494 0.151 13.42 17.8206 0.9979 1940621 CBMicro_030058 Cc1onc(c1C(=O)NCCNc2ccc(cc2Cl)[N+](=O)[O-])c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O21 compound treatment 0.33 -0.011 -0.92 0.339 -0.00361 -0.32 -0.8741 -0.9008 1940622 CBMicro_030059 Clc1cccc(/C=N/NC(=O)CSc2nc3ccccc3[nH]2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O22 compound treatment 0.344 0.00297 0.25 0.345 0.00239 0.21 0.3237 0.9971 1561014 CBMicro_030060 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O23 positive control 0.087 -0.254 -21.09 0.091 -0.252 -22.3 -30.6799 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 O24 positive control 0.093 -0.248 -20.59 0.094 -0.249 -22.03 -30.1397 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P01 mock treatment 0.342 9.67E-4 0.08 0.341 -0.00161 -0.14 -0.0443 -0.2704 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P02 mock treatment 0.343 0.00197 0.16 0.351 0.00839 0.74 0.641 0.8423 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P03 compound treatment 0.345 0.00397 0.33 0.337 -0.00561 -0.5 -0.1189 -0.1993 1402148 CBMicro_030061 Cc1ccccc1N2OC3C(C2c4cccs4)C(=O)N(C3=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P04 compound treatment 0.341 -3.33E-5 0.0 0.343 3.87E-4 0.03 0.0223 0.648 1940623 CBMicro_030062 COC(=O)C1=NN(C(=O)c2ccccc2)C(O)(C1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P05 compound treatment 0.33 -0.011 -0.92 0.346 0.00339 0.3 -0.4354 -0.4517 1940624 CBMicro_030063 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P06 compound treatment 0.345 0.00397 0.33 0.355 0.0124 1.1 1.0091 0.8805 1940625 CBMicro_030064 [O-][N+](=O)c1cccc(/C=C(\NC(=O)c2ccccc2)/C(=O)NCCc3c[nH]c4ccccc34)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P07 compound treatment 0.343 0.00197 0.16 0.341 -0.00161 -0.14 0.0144 0.0663 1940626 CBMicro_030065 Cc1nc(N)sc1c2csc(Nc3ccc(cc3)S(=O)(=O)N)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P08 compound treatment 0.338 -0.00303 -0.25 0.338 -0.00461 -0.41 -0.4671 -0.9729 1940627 CBMicro_030066 CN1C(=O)N(C)C(=O)C(=C(C)Nc2ccc(C)cc2)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P09 compound treatment 0.328 -0.013 -1.08 0.332 -0.0106 -0.94 -1.4302 -0.9976 1940628 CBMicro_030067 COc1cccc(C=C2C(=O)NC(=S)NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P10 compound treatment 0.342 9.67E-4 0.08 0.347 0.00439 0.39 0.3317 0.8355 1940629 CBMicro_030068 Cc1cc(C)nc(SCC(=O)Nc2ccccc2[N+](=O)[O-])n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P11 compound treatment 0.33 -0.011 -0.92 0.336 -0.00661 -0.59 -1.0621 -0.9767 1428220 CBMicro_030069 CNC(=C1C(=O)N(C)C(=S)N(C)C1=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P12 compound treatment 0.338 -0.00303 -0.25 0.341 -0.00161 -0.14 -0.2791 -0.964 1169201 CBMicro_030070 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccnc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P13 compound treatment 0.331 -0.01 -0.83 0.342 -6.13E-4 -0.05 -0.6274 -0.7516 1498766 CBMicro_030071 CNC(=C1C(=O)N(C)C(=O)N(C)C1=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P14 compound treatment 0.336 -0.00503 -0.42 0.343 3.87E-4 0.03 -0.2712 -0.6469 1940630 CBMicro_030072 O=C(CSc1nnnn1c2ccccc2)Nc3nncs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P15 compound treatment 0.342 9.67E-4 0.08 0.356 0.0134 1.19 0.8957 0.7532 1325822 CBMicro_030073 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)NCc2ccco2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P16 compound treatment 0.325 -0.016 -1.33 0.333 -0.00961 -0.85 -1.5436 -0.9767 1362705 CBMicro_030074 Oc1ccc(cc1O)c2cn3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P17 compound treatment 0.358 0.017 1.41 0.355 0.0124 1.1 1.7722 0.9924 1128252 CBMicro_030075 COc1cc2ccccc2cc1C(=O)Nc3sc4CCCCc4c3C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P18 compound treatment 0.336 -0.00503 -0.42 0.331 -0.0116 -1.03 -1.0232 -0.9212 1940631 CBMicro_030076 Cc1cc(C)nc(SCc2ccccc2Cl)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P19 compound treatment 0.329 -0.012 -1.0 0.331 -0.0116 -1.03 -1.4341 -0.9999 1166215 CBMicro_030077 CC(C)(C)c1ccccc1OCC(=O)Nc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P20 compound treatment 0.337 -0.00403 -0.33 0.349 0.00639 0.57 0.1635 0.2486 1940632 CBMicro_030078 CCN(CC)c1ccc(NC=C2C(=O)N(C)C(=O)N(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P21 compound treatment 0.35 0.00897 0.74 0.348 0.00539 0.48 0.864 0.9769 1940633 CBMicro_030079 COc1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)c(C)c3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P22 compound treatment 0.432 0.091 7.55 0.433 0.0904 8.01 11.0042 0.9996 1393857 CBMicro_030080 COc1ccc(cc1OC)C(NC(=O)c2ccccc2)c3c(O)ccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P23 positive control 0.091 -0.25 -20.76 0.091 -0.252 -22.3 -30.4451 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.779 P24 positive control 0.094 -0.247 -20.51 0.096 -0.247 -21.86 -29.9557 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A01 mock treatment 0.336 -0.00519 -0.43 0.337 -0.00371 -0.33 -0.5373 -0.991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A02 mock treatment 0.353 0.0118 0.98 0.351 0.0103 0.91 1.3379 0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A03 compound treatment 0.338 -0.00319 -0.27 0.339 -0.00171 -0.15 -0.2946 -0.9648 1940770 CBMicro_030401 Cn1c(/C=C/c2ccc3OCOc3c2)nc4ccccc4c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A04 compound treatment 0.341 -1.94E-4 -0.02 0.339 -0.00171 -0.15 -0.1185 -0.7777 1940771 CBMicro_030402 Brc1ccccc1NC(=O)CSc2nnnn2c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A05 compound treatment 0.335 -0.00619 -0.51 0.332 -0.00871 -0.77 -0.9094 -0.9805 1509760 CBMicro_030403 O=C(OCc1nc2c(ccc3ccccc23)[nH]1)C4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A06 compound treatment 0.34 -0.00119 -0.1 0.345 0.00429 0.38 0.1988 0.5059 1863908 CBMicro_030404 CC(C)c1cccc(C(C)C)c1NC(=O)COc2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A07 compound treatment 0.34 -0.00119 -0.1 0.341 2.9E-4 0.03 -0.0519 -0.5067 1565163 CBMicro_030405 CCOC(=O)Cc1csc(NC(=O)COc2cccc(Cl)c2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A08 compound treatment 0.327 -0.0142 -1.18 0.328 -0.0127 -1.13 -1.6297 -0.9997 1344364 CBMicro_030406 CCN(CC)c1ccc(NC(=O)Cc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A09 compound treatment 0.368 0.0268 2.23 0.362 0.0213 1.89 2.9078 0.9966 1704307 CBMicro_030407 CCCOC(=O)c1ccc(NC(=O)COc2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A10 compound treatment 0.347 0.00581 0.48 0.346 0.00529 0.47 0.6724 0.9999 1218626 CBMicro_030408 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)COc3ccc(C)cc3C)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A11 compound treatment 0.348 0.00681 0.57 0.351 0.0103 0.91 1.0444 0.9735 1391538 CBMicro_030409 CC(C)OC(=O)c1ccc(NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A12 compound treatment 0.339 -0.00219 -0.18 0.337 -0.00371 -0.33 -0.3612 -0.9612 1940772 CBMicro_030410 Cc1ccc(NC(=O)C(Cl)Cl)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A13 compound treatment 0.371 0.0298 2.47 0.367 0.0263 2.33 3.3972 0.9995 1940773 CBMicro_030411 COc1ccc(CCNC(=O)/C=C/c2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A14 compound treatment 0.344 0.00281 0.23 0.343 0.00229 0.2 0.3083 0.9976 1326623 CBMicro_030412 Cc1ccc(NC(=O)C2CN(C(=O)C2)c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A15 compound treatment 0.344 0.00281 0.23 0.346 0.00529 0.47 0.4963 0.9479 1940774 CBMicro_030413 COc1ccc(NC(=O)C(=O)NCCOC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A16 compound treatment 0.338 -0.00319 -0.27 0.34 -7.1E-4 -0.06 -0.2319 -0.8512 1330040 CBMicro_030414 COc1ccc(NC(=O)C2CN(C(=O)C2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A17 compound treatment 0.334 -0.00719 -0.6 0.337 -0.00371 -0.33 -0.6548 -0.9605 1940775 CBMicro_030415 Cc1cc(C)n2c(SCCO)nnc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A18 compound treatment 0.332 -0.00919 -0.76 0.338 -0.00271 -0.24 -0.7095 -0.8867 1940776 CBMicro_030416 C/C(=C\C(=O)c1ccccc1)/Nc2ccc(Br)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A19 compound treatment 0.343 0.00181 0.15 0.344 0.00329 0.29 0.3122 0.9522 1564372 CBMicro_030417 COC(=O)c1ccccc1NC(=O)COc2cccc(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A20 compound treatment 0.362 0.0208 1.73 0.364 0.0233 2.06 2.6809 0.9961 1940777 CBMicro_030418 COC(=O)CN1C(=O)/C(=C\c2cccs2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A21 compound treatment 0.353 0.0118 0.98 0.35 0.00929 0.82 1.2753 0.9962 1940778 CBMicro_030419 O=c1[nH]c(/C=C/c2ccc3OCOc3c2)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A22 compound treatment 0.336 -0.00519 -0.43 0.33 -0.0107 -0.95 -0.976 -0.9363 1211695 CBMicro_030420 Cc1occc1C(=O)Nc2ccc(cc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A23 positive control 0.082 -0.259 -21.52 0.084 -0.257 -22.75 -31.3023 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 A24 positive control 0.085 -0.256 -21.27 0.088 -0.253 -22.4 -30.8755 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B01 mock treatment 0.335 -0.00619 -0.51 0.325 -0.0157 -1.39 -1.348 -0.9083 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B02 mock treatment 0.345 0.00381 0.32 0.341 2.9E-4 0.03 0.2416 0.7622 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B03 compound treatment 0.332 -0.00919 -0.76 0.335 -0.00571 -0.51 -0.8975 -0.9801 1940779 CBMicro_030421 Cc1ccc(N/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B04 compound treatment 0.341 -1.94E-4 -0.02 0.342 0.00129 0.11 0.0695 0.6018 1524547 CBMicro_030422 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4)nc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B05 compound treatment 0.333 -0.00819 -0.68 0.34 -7.1E-4 -0.06 -0.5255 -0.7692 1940780 CBMicro_030423 CCOCCOC(=O)c1ccc(NC(=O)COc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B06 compound treatment 0.344 0.00281 0.23 0.345 0.00429 0.38 0.4336 0.9724 1716647 CBMicro_030424 CC(C)OC(=O)c1c(N)scc1c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B07 compound treatment 0.343 0.00181 0.15 0.332 -0.00871 -0.77 -0.4397 -0.5593 1430878 CBMicro_030425 CCc1ccc(cc1)c2cc(C(=O)NC(C)(C)C)c3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B08 compound treatment 0.338 -0.00319 -0.27 0.337 -0.00371 -0.33 -0.4199 -0.9943 1242119 CBMicro_030426 COc1ccc(CC(=O)NCc2ccc3OCOc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B09 compound treatment 0.341 -1.94E-4 -0.02 0.339 -0.00171 -0.15 -0.1185 -0.7777 1940781 CBMicro_030427 CC(=O)c1ccc(NC(=O)c2ccoc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B10 compound treatment 0.337 -0.00419 -0.35 0.336 -0.00471 -0.42 -0.5413 -0.9959 1401519 CBMicro_030428 O=C(NCc1ccccn1)C(Sc2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B11 compound treatment 0.336 -0.00519 -0.43 0.331 -0.00971 -0.86 -0.9133 -0.949 1940782 CBMicro_030429 COc1ccc2ncn(c3ccccc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B12 compound treatment 0.332 -0.00919 -0.76 0.33 -0.0107 -0.95 -1.2108 -0.9942 1245496 CBMicro_030430 O=C(Nc1ccccc1)N2CCc3ccccc3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B13 compound treatment 0.336 -0.00519 -0.43 0.339 -0.00171 -0.15 -0.412 -0.9015 1697829 CBMicro_030431 OC(=O)c1ccc(Oc2ccc(cc2)c3ccc(Oc4ccc(C(=O)O)c(c4)C(=O)O)cc3)cc1C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B14 compound treatment 0.326 -0.0152 -1.26 0.336 -0.00471 -0.42 -1.187 -0.8934 1940783 CBMicro_030432 CCCOC(=O)c1c(N)scc1c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B15 compound treatment 0.349 0.00781 0.65 0.328 -0.0127 -1.13 -0.3382 -0.2602 1697980 CBMicro_030433 CCOC(=O)c1sc(NC(=O)COc2c(C)cccc2C)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B16 compound treatment 0.338 -0.00319 -0.27 0.335 -0.00571 -0.51 -0.5453 -0.9545 1940784 CBMicro_030434 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2cccc(c2)[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B17 compound treatment 0.331 -0.0102 -0.85 0.338 -0.00271 -0.24 -0.7682 -0.8733 1940785 CBMicro_030435 Cc1ccc(o1)C(=O)NCCCn2ccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B18 compound treatment 0.344 0.00281 0.23 0.34 -7.1E-4 -0.06 0.1203 0.4984 1314985 CBMicro_030436 CCc1c(C)sc(NC(=O)c2ccc(F)cc2)c1C(=O)OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B19 compound treatment 0.339 -0.00219 -0.18 0.344 0.00329 0.29 0.0774 0.2252 1269185 CBMicro_030437 Cc1ccc(CNC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B20 compound treatment 0.334 -0.00719 -0.6 0.331 -0.00971 -0.86 -1.0307 -0.9841 1940786 CBMicro_030438 Brc1cccc(NC(=O)C2CC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B21 compound treatment 0.339 -0.00219 -0.18 0.339 -0.00171 -0.15 -0.2359 -0.9958 1940787 CBMicro_030439 OCCCNC(=O)C(=O)Nc1cccc(Cl)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B22 compound treatment 0.333 -0.00819 -0.68 0.334 -0.00671 -0.59 -0.9015 -0.9978 1252514 CBMicro_030440 COc1cccc(OC)c1C(=O)Nc2ccc(C)cc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B23 positive control 0.083 -0.258 -21.43 0.086 -0.255 -22.57 -31.1182 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 B24 positive control 0.085 -0.256 -21.27 0.087 -0.254 -22.48 -30.9381 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C01 mock treatment 0.342 8.06E-4 0.07 0.336 -0.00471 -0.42 -0.2478 -0.5862 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C02 mock treatment 0.355 0.0138 1.15 0.341 2.9E-4 0.03 0.8287 0.7228 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C03 compound treatment 0.315 -0.0262 -2.17 0.337 -0.00371 -0.33 -1.7701 -0.8049 1730896 CBMicro_030441 Clc1ccccc1OCC(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C04 compound treatment 0.34 -0.00119 -0.1 0.348 0.00729 0.65 0.3868 0.5917 1195961 CBMicro_030442 Cc1ccc(C)c(Nc2nc(nc3ccccc23)c4ccncc4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C05 compound treatment 0.345 0.00381 0.32 0.315 -0.0257 -2.28 -1.3876 -0.6033 1262971 CBMicro_030443 CC(=O)Nc1nc2ccc(cc2s1)c3nc4cc(NC(=O)C)ccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C06 compound treatment 0.364 0.0228 1.89 0.367 0.0263 2.33 2.9863 0.9947 1940788 CBMicro_030444 COc1ccc(cc1)N2C(=O)C(=C(Nc3ccccc3F)C2=O)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C07 compound treatment 0.336 -0.00519 -0.43 0.336 -0.00471 -0.42 -0.6 -0.9999 1433619 CBMicro_030445 CCOC(=O)c1cccc(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C08 compound treatment 0.334 -0.00719 -0.6 0.34 -7.1E-4 -0.06 -0.4668 -0.7773 1062988 CBMicro_030446 ClC(Cl)C(=O)NCc1ccc2OCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C09 compound treatment 0.35 0.00881 0.73 0.349 0.00829 0.73 1.0365 1.0 1523935 CBMicro_030447 Cc1cc(OCC(=O)Nc2ccccc2F)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C10 compound treatment 0.372 0.0308 2.56 0.374 0.0333 2.95 3.8946 0.9975 1584355 CBMicro_030448 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3cc(Cl)ccc3C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C11 compound treatment 0.318 -0.0232 -1.93 0.321 -0.0197 -1.75 -2.5966 -0.9988 1662633 CBMicro_030449 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(c2)S(=O)(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C12 compound treatment 0.34 -0.00119 -0.1 0.339 -0.00171 -0.15 -0.1772 -0.9788 1634864 CBMicro_030450 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C13 compound treatment 0.373 0.0318 2.64 0.375 0.0343 3.04 4.0159 0.9975 1652874 CBMicro_030451 CCCC1CCc2c(C(=O)N)c(NC(=O)Cc3ccccc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C14 compound treatment 0.35 0.00881 0.73 0.351 0.0103 0.91 1.1618 0.994 1488893 CBMicro_030452 CC(NC(=O)C1CN(C(=O)C1)c2ccc(Br)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C15 compound treatment 0.233 -0.108 -8.98 0.234 -0.107 -9.46 -13.0383 -0.9997 1940789 CBMicro_030453 CN(CCO)C1=NS(=O)(=O)c2cc(ccc12)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C16 compound treatment 0.353 0.0118 0.98 0.36 0.0193 1.71 1.9019 0.9651 1125879 CBMicro_030454 O=C(CSc1nc2ccccc2s1)NCC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C17 compound treatment 0.347 0.00581 0.48 0.351 0.0103 0.91 0.9857 0.9556 1642324 CBMicro_030455 COC(=O)c1cc(Cl)c(NC(=O)c2ccco2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C18 compound treatment 0.389 0.0478 3.97 0.39 0.0493 4.37 5.8952 0.9989 1940790 CBMicro_030456 CC(=O)Nc1ccc(N/C(=C/C(=O)c2ccc(Br)cc2)/C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C19 compound treatment 0.347 0.00581 0.48 0.352 0.0113 1.0 1.0484 0.9439 1940791 CBMicro_030457 COC(=O)C1CCc2sc(NC(=O)CCCOc3ccccc3)c(C(=O)OC)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C20 compound treatment 0.339 -0.00219 -0.18 0.339 -0.00171 -0.15 -0.2359 -0.9958 1241014 CBMicro_030458 Cc1c(OCc2ccccc2F)ccc3c4CCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C21 compound treatment 0.418 0.0768 6.38 0.381 0.0403 3.57 7.0336 0.9624 1940792 CBMicro_030459 Fc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C22 compound treatment 0.335 -0.00619 -0.51 0.334 -0.00671 -0.59 -0.784 -0.9974 1701367 CBMicro_030460 Cc1ccc(o1)C(=O)Nc2ccc(cc2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C23 positive control 0.081 -0.26 -21.6 0.085 -0.256 -22.66 -31.2983 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 C24 positive control 0.084 -0.257 -21.35 0.089 -0.252 -22.31 -30.8715 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D01 mock treatment 0.341 -1.94E-4 -0.02 0.341 2.9E-4 0.03 0.0068 0.2252 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D02 mock treatment 0.345 0.00381 0.32 0.34 -7.1E-4 -0.06 0.179 0.5555 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D03 compound treatment 0.335 -0.00619 -0.51 0.334 -0.00671 -0.59 -0.784 -0.9974 1642288 CBMicro_030461 Clc1cccc(c1)N(CC(=O)Nc2cccc3cccnc23)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D04 compound treatment 0.346 0.00481 0.4 0.347 0.00629 0.56 0.6763 0.9866 1940793 CBMicro_030462 CC(=O)c1ccc2c3CCCCc3[nH]c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D05 compound treatment 0.346 0.00481 0.4 0.341 2.9E-4 0.03 0.3003 0.7511 1940794 CBMicro_030463 NC(=O)c1c(NC(=O)C2C(C3CC2C=C3)C(=O)O)sc4CCCCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D06 compound treatment 0.331 -0.0102 -0.85 0.334 -0.00671 -0.59 -1.0189 -0.9851 1656003 CBMicro_030464 CC(C)OC(=O)c1c(N)scc1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D07 compound treatment 0.358 0.0168 1.4 0.348 0.00729 0.65 1.4434 0.9388 1593671 CBMicro_030465 CCCOc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3ccco3)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D08 compound treatment 0.33 -0.0112 -0.93 0.339 -0.00171 -0.15 -0.7642 -0.8117 1940795 CBMicro_030466 COc1cc(ccc1O)/C(=N/NC(=O)C(O)(c2ccccc2)c3ccccc3)/C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D09 compound treatment 0.337 -0.00419 -0.35 0.341 2.9E-4 0.03 -0.228 -0.6531 1940796 CBMicro_030467 Clc1ccc(CC(=O)Nc2cc(Cl)c(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D10 compound treatment 0.333 -0.00819 -0.68 0.333 -0.00771 -0.68 -0.9641 -1.0 1940797 CBMicro_030468 CC(Oc1cccc(Cl)c1)C(=O)Nc2cc(ccc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D11 compound treatment 0.324 -0.0172 -1.43 0.339 -0.00171 -0.15 -1.1165 -0.7778 1266128 CBMicro_030469 CC(C)(C)c1cc(Br)ccc1OCC(=O)Nc2ccccc2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D12 compound treatment 0.353 0.0118 0.98 0.359 0.0183 1.62 1.8392 0.971 1273716 CBMicro_030470 COc1ccc(cc1)C(=O)Nc2nc3ccc(Br)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D13 compound treatment 0.336 -0.00519 -0.43 0.344 0.00329 0.29 -0.0987 -0.1896 1940798 CBMicro_030471 CC(=O)OCCCN1C(=O)c2ccccc2C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D14 compound treatment 0.334 -0.00719 -0.6 0.329 -0.0117 -1.04 -1.1561 -0.9656 1940799 CBMicro_030472 COC(=O)c1c(N)scc1c2cccc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D15 compound treatment 0.344 0.00281 0.23 0.332 -0.00871 -0.77 -0.381 -0.4726 1360905 CBMicro_030473 Cc1cccc(C)c1NC(=O)CN2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D16 compound treatment 0.342 8.06E-4 0.07 0.344 0.00329 0.29 0.2535 0.8474 1493231 CBMicro_030474 COc1ccccc1C(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D17 compound treatment 0.357 0.0158 1.31 0.351 0.0103 0.91 1.5727 0.9842 1480639 CBMicro_030475 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2c(C)cc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D18 compound treatment 0.343 0.00181 0.15 0.336 -0.00471 -0.42 -0.1891 -0.4263 1228774 CBMicro_030476 Cc1occc1C(=O)Nc2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D19 compound treatment 0.328 -0.0132 -1.1 0.329 -0.0117 -1.04 -1.5083 -0.9996 1940800 CBMicro_030477 Cc1occc1C(=O)Nc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D20 compound treatment 0.356 0.0148 1.23 0.354 0.0133 1.18 1.702 0.9998 1180629 CBMicro_030478 COc1ccc(NC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D21 compound treatment 0.362 0.0208 1.73 0.359 0.0183 1.62 2.3676 0.9995 1940801 CBMicro_030479 CCCCOc1ccc(NC(=O)C2CN(C(=O)C2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D22 compound treatment 0.336 -0.00519 -0.43 0.337 -0.00371 -0.33 -0.5373 -0.991 1940802 CBMicro_030480 CCOC(=O)C1=C(Nc2ccc(C)cc2)S/C(=C\c3ccc(cc3)[N+](=O)[O-])/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D23 positive control 0.082 -0.259 -21.52 0.088 -0.253 -22.4 -31.0516 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 D24 positive control 0.086 -0.255 -21.19 0.09 -0.251 -22.22 -30.6914 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E01 mock treatment 0.335 -0.00619 -0.51 0.332 -0.00871 -0.77 -0.9094 -0.9805 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E02 mock treatment 0.346 0.00481 0.4 0.343 0.00229 0.2 0.4257 0.9508 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E03 compound treatment 0.341 -1.94E-4 -0.02 0.341 2.9E-4 0.03 0.0068 0.2252 1940803 CBMicro_030481 CC1=NN(C(=O)OC(C)(C)C)C(O)(C1)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E04 compound treatment 0.347 0.00581 0.48 0.338 -0.00271 -0.24 0.1711 0.3176 1940804 CBMicro_030482 COc1cccc(NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E05 compound treatment 0.318 -0.0232 -1.93 0.322 -0.0187 -1.66 -2.534 -0.9972 1433750 CBMicro_030483 Oc1ccc(cc1)c2nc3ccc(NC(=O)C4CCCCC4)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E06 compound treatment 0.336 -0.00519 -0.43 0.342 0.00129 0.11 -0.224 -0.5022 1502746 CBMicro_030484 CC(C)c1cccc(C)c1NC(=O)Nc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E07 compound treatment 0.3 -0.0412 -3.42 0.311 -0.0297 -2.63 -4.28 -0.9917 1940805 CBMicro_030485 CCCCOC(=O)c1cccc(NC(=O)c2ccc(Cl)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E08 compound treatment 0.373 0.0318 2.64 0.365 0.0243 2.15 3.3893 0.9949 1940806 CBMicro_030486 Cc1ccccc1C(=O)Nc2nc3ccc(Br)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E09 compound treatment 0.328 -0.0132 -1.1 0.343 0.00229 0.2 -0.631 -0.5664 1668411 CBMicro_030487 CCOC(=O)c1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E10 compound treatment 0.351 0.00981 0.81 0.347 0.00629 0.56 0.9699 0.9829 1193301 CBMicro_030488 Cc1ccc(cc1)c2ccc(OCC(=O)NCc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E11 compound treatment 0.33 -0.0112 -0.93 0.337 -0.00371 -0.33 -0.8896 -0.9025 1460687 CBMicro_030489 COc1cccc(c1)C(=O)Oc2ccc3c(C)cc(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E12 compound treatment 0.339 -0.00219 -0.18 0.35 0.00929 0.82 0.4534 0.5377 1940807 CBMicro_030490 [O-][N+](=O)c1cccc(/C=C/C(=O)Nc2ccc(F)c(Cl)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E13 compound treatment 0.352 0.0108 0.9 0.37 0.0293 2.6 2.4699 0.8993 1167262 CBMicro_030491 COc1ccc(cc1)c2cc(C(=O)Nc3c(Cl)cccc3Cl)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E14 compound treatment 0.342 8.06E-4 0.07 0.34 -7.1E-4 -0.06 0.0029 0.0312 1592583 CBMicro_030492 Cc1ccc(C)c(NC(=O)C2CN(C(=O)C2)c3ccc(Br)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E15 compound treatment 0.256 -0.0852 -7.07 0.26 -0.0807 -7.15 -10.0588 -1.0 1940808 CBMicro_030493 CCc1ccccc1NC2=NS(=O)(=O)c3cc(ccc23)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E16 compound treatment 0.33 -0.0112 -0.93 0.336 -0.00471 -0.42 -0.9522 -0.9347 1940809 CBMicro_030494 CCc1ccccc1NC(=O)C(=O)NCCOC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E17 compound treatment 0.337 -0.00419 -0.35 0.33 -0.0107 -0.95 -0.9173 -0.9074 1940810 CBMicro_030495 Cc1cc(C)n2c(SCC#C)nnc2n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E18 compound treatment 0.325 -0.0162 -1.34 0.323 -0.0177 -1.57 -2.0604 -0.997 1548928 CBMicro_030496 CCOc1ccccc1NC(=O)CSCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E19 compound treatment 0.375 0.0338 2.81 0.377 0.0363 3.22 4.2587 0.9977 1940811 CBMicro_030497 Cc1cccc(OCC(=O)Nc2ccccc2[N+](=O)[O-])c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E20 compound treatment 0.34 -0.00119 -0.1 0.335 -0.00571 -0.51 -0.4279 -0.8298 1680873 CBMicro_030498 COC(=O)c1c(NC(=O)COc2ccc(C)cc2C)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E21 compound treatment 0.348 0.00681 0.57 0.356 0.0153 1.36 1.3577 0.9248 1940812 CBMicro_030499 CCOC(=O)C(=CNc1ccc(cc1)C(=O)OC)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E22 compound treatment 0.327 -0.0142 -1.18 0.331 -0.00971 -0.86 -1.4417 -0.9881 1741257 CBMicro_030500 CCc1ccc(NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E23 positive control 0.083 -0.258 -21.43 0.087 -0.254 -22.48 -31.0556 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 E24 positive control 0.088 -0.253 -21.02 0.094 -0.247 -21.86 -30.3234 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F01 mock treatment 0.334 -0.00719 -0.6 0.348 0.00729 0.65 0.0346 0.0393 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F02 mock treatment 0.34 -0.00119 -0.1 0.341 2.9E-4 0.03 -0.0519 -0.5067 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F03 compound treatment 0.344 0.00281 0.23 0.34 -7.1E-4 -0.06 0.1203 0.4984 1257727 CBMicro_030501 COc1ccc(CCNC(=O)CSc2nc3ccccc3s2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F04 compound treatment 0.346 0.00481 0.4 0.336 -0.00471 -0.42 -0.013 -0.0225 1940813 CBMicro_030502 OCCCNC(=O)CCCSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F05 compound treatment 0.331 -0.0102 -0.85 0.339 -0.00171 -0.15 -0.7055 -0.8207 1940814 CBMicro_030503 CC(C)(C)c1ccc(/C=C/C(=O)NCc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F06 compound treatment 0.328 -0.0132 -1.1 0.331 -0.00971 -0.86 -1.383 -0.9929 1940815 CBMicro_030504 CCOC(=O)c1c(NC(=O)C2(C)CC2(Br)Br)sc(C)c1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F07 compound treatment 0.337 -0.00419 -0.35 0.336 -0.00471 -0.42 -0.5413 -0.9959 1323214 CBMicro_030505 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3nncs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F08 compound treatment 0.343 0.00181 0.15 0.338 -0.00271 -0.24 -0.0638 -0.2252 1245959 CBMicro_030506 Cc1sc2nc(SCC(=O)N3CCCCC3)n(CC=C)c(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F09 compound treatment 0.342 8.06E-4 0.07 0.326 -0.0147 -1.3 -0.8744 -0.6699 1685089 CBMicro_030507 CCC(Oc1ccccc1)C(=O)NC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F10 compound treatment 0.333 -0.00819 -0.68 0.337 -0.00371 -0.33 -0.7135 -0.9443 1940816 CBMicro_030508 Cc1cc(C)nc(NC(=N)NNC(=O)c2cccnc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F11 compound treatment 0.365 0.0238 1.98 0.362 0.0213 1.89 2.7317 0.9997 1940817 CBMicro_030509 OC(=O)CC1S/C(=N\N=C\c2ccc(cc2)N3CCOCC3)/NC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F12 compound treatment 0.328 -0.0132 -1.1 0.324 -0.0167 -1.48 -1.8216 -0.989 1677547 CBMicro_030510 COC(=O)c1c(N)sc(C)c1c2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F13 compound treatment 0.363 0.0218 1.81 0.367 0.0263 2.33 2.9276 0.9922 1610160 CBMicro_030511 CC(C)COC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F14 compound treatment 0.35 0.00881 0.73 0.356 0.0153 1.36 1.4751 0.9581 1940818 CBMicro_030512 Cc1ccc(cc1)N2C(=O)C(=C(Nc3cccc(C)c3C)C2=O)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F15 compound treatment 0.346 0.00481 0.4 0.337 -0.00371 -0.33 0.0497 0.0961 1940819 CBMicro_030513 Cc1ccc(cc1NC(=O)C2CC2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F16 compound treatment 0.373 0.0318 2.64 0.367 0.0263 2.33 3.5146 0.9981 1526894 CBMicro_030514 Clc1ccc(CC(=O)NC(c2ccccc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F17 compound treatment 0.336 -0.00519 -0.43 0.34 -7.1E-4 -0.06 -0.3494 -0.8018 1610597 CBMicro_030515 Cc1ccc(o1)C(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F18 compound treatment 0.339 -0.00219 -0.18 0.362 0.0213 1.89 1.2054 0.6359 1190062 CBMicro_030516 CC(Oc1ccccc1)C(=O)NC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F19 compound treatment 0.338 -0.00319 -0.27 0.344 0.00329 0.29 0.0187 0.0475 1940820 CBMicro_030517 [O-][N+](=O)c1cccc(/C=C/C(=O)N2CCN(Cc3ccccc3)CC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F20 compound treatment 0.34 -0.00119 -0.1 0.339 -0.00171 -0.15 -0.1772 -0.9788 1586826 CBMicro_030518 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CN2C(=O)c3ccccc3C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F21 compound treatment 0.351 0.00981 0.81 0.348 0.00729 0.65 1.0325 0.9934 1554821 CBMicro_030519 CCC1CCc2c(C(=O)OC)c(NC(=O)Cc3ccccc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F22 compound treatment 0.339 -0.00219 -0.18 0.329 -0.0117 -1.04 -0.8626 -0.8187 1528615 CBMicro_030520 OC(=O)c1ccccc1SC2CC(=O)N(Cc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F23 positive control 0.084 -0.257 -21.35 0.087 -0.254 -22.48 -30.9968 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 F24 positive control 0.087 -0.254 -21.1 0.091 -0.25 -22.13 -30.5701 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G01 mock treatment 0.33 -0.0112 -0.93 0.335 -0.00571 -0.51 -1.0149 -0.9592 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G02 mock treatment 0.336 -0.00519 -0.43 0.335 -0.00571 -0.51 -0.6627 -0.9968 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G03 compound treatment 0.503 0.162 13.43 0.5 0.159 14.12 19.4805 0.9997 1940821 CBMicro_030521 C/C(=C\C(=O)c1ccncc1)/Nc2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G04 compound treatment 0.335 -0.00619 -0.51 0.331 -0.00971 -0.86 -0.972 -0.9697 1940822 CBMicro_030522 Nc1nnc(SCC(=O)NCCOc2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G05 compound treatment 0.344 0.00281 0.23 0.342 0.00129 0.11 0.2456 0.9463 1287755 CBMicro_030523 Cn1cc(N)c(n1)C(=O)Nc2ccc3C(=O)NC(=O)c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G06 compound treatment 0.326 -0.0152 -1.26 0.333 -0.00771 -0.68 -1.375 -0.9585 1940823 CBMicro_030524 Cc1cccc(C)c1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G07 compound treatment 0.339 -0.00219 -0.18 0.346 0.00529 0.47 0.2028 0.4031 1940824 CBMicro_030525 CN1C(=O)/C(=C\2/SC(=O)N(C2=S)c3cccc(Cl)c3)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G08 compound treatment 0.339 -0.00219 -0.18 0.338 -0.00271 -0.24 -0.2986 -0.9907 1940825 CBMicro_030526 CC(C)OC(=O)c1sc(NC(=O)/C=C/c2ccc3OCOc3c2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G09 compound treatment 0.325 -0.0162 -1.34 0.321 -0.0197 -1.75 -2.1857 -0.9916 1273935 CBMicro_030527 CCOc1ccccc1NC(=O)COc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G10 compound treatment 0.352 0.0108 0.9 0.357 0.0163 1.44 1.6552 0.9738 1735200 CBMicro_030528 Cc1ccc(NC(=O)COc2cccc(C)c2C)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G11 compound treatment 0.34 -0.00119 -0.1 0.341 2.9E-4 0.03 -0.0519 -0.5067 1940826 CBMicro_030529 CC(C)(C)c1ccc(/C=C/C(=O)N2CCc3ccccc3C2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G12 compound treatment 0.325 -0.0162 -1.34 0.312 -0.0287 -2.54 -2.7497 -0.9555 1940827 CBMicro_030530 Cc1cccc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G13 compound treatment 0.333 -0.00819 -0.68 0.325 -0.0157 -1.39 -1.4654 -0.9457 1940828 CBMicro_030531 Clc1ccc(/C=C/C(=O)NCc2ccccn2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G14 compound treatment 0.339 -0.00219 -0.18 0.337 -0.00371 -0.33 -0.3612 -0.9612 1940829 CBMicro_030532 Cc1cccc(NC(=O)C(=O)NCCOC=C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G15 compound treatment 0.335 -0.00619 -0.51 0.333 -0.00771 -0.68 -0.8467 -0.9902 1940830 CBMicro_030533 CN(CCO)C1=NS(=O)(=O)c2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G16 compound treatment 0.331 -0.0102 -0.85 0.332 -0.00871 -0.77 -1.1442 -0.9989 1940831 CBMicro_030534 Cc1ccccc1NC(=O)C(=O)NCCOC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G17 compound treatment 0.333 -0.00819 -0.68 0.334 -0.00671 -0.59 -0.9015 -0.9978 1940832 CBMicro_030535 CCN(CC)CCNC(=O)c1ccccc1C(=O)c2ncc[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G18 compound treatment 0.453 0.112 9.28 0.453 0.112 9.95 13.6001 0.9994 1940833 CBMicro_030536 Cc1cc(N/C=C/C(=O)c2ccccc2)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G19 compound treatment 0.35 0.00881 0.73 0.355 0.0143 1.27 1.4125 0.9659 1383672 CBMicro_030537 CCc1ccc(NC(=O)COc2cccc(C)c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G20 compound treatment 0.334 -0.00719 -0.6 0.332 -0.00871 -0.77 -0.9681 -0.992 1940834 CBMicro_030538 CCOC(=O)c1ccccc1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G21 compound treatment 0.336 -0.00519 -0.43 0.333 -0.00771 -0.68 -0.788 -0.9754 1940835 CBMicro_030539 COCCN(CCOC)Cc1c(C)nc2ccccc2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G22 compound treatment 0.334 -0.00719 -0.6 0.326 -0.0147 -1.3 -1.3441 -0.9374 1940836 CBMicro_030540 CC(C)c1ccc(C)cc1OCCNC(=O)c2cc(F)c(F)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G23 positive control 0.085 -0.256 -21.27 0.089 -0.252 -22.31 -30.8128 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 G24 positive control 0.09 -0.251 -20.85 0.092 -0.249 -22.04 -30.3313 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H01 mock treatment 0.332 -0.00919 -0.76 0.337 -0.00371 -0.33 -0.7722 -0.9292 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H02 mock treatment 0.339 -0.00219 -0.18 0.339 -0.00171 -0.15 -0.2359 -0.9958 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H03 compound treatment 0.328 -0.0132 -1.1 0.331 -0.00971 -0.86 -1.383 -0.9929 1940837 CBMicro_030541 Cc1oc(cc1CSCc2ccoc2C(=O)O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H04 compound treatment 0.612 0.271 22.48 0.614 0.273 24.22 33.023 0.9993 1940838 CBMicro_030542 CCOc1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)cc([N+](=O)[O-])c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H05 compound treatment 0.335 -0.00619 -0.51 0.349 0.00829 0.73 0.1559 0.1739 1940839 CBMicro_030543 CC(C)(C)c1ccc(/C=C/C(=O)Nc2ccccc2C(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H06 compound treatment 0.357 0.0158 1.31 0.369 0.0283 2.51 2.7007 0.9544 1335450 CBMicro_030544 CCOC(=O)c1c(N)sc(C)c1c2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H07 compound treatment 0.336 -0.00519 -0.43 0.33 -0.0107 -0.95 -0.976 -0.9363 1940840 CBMicro_030545 CCSc1nnc(NC(=O)/C=C/c2ccc(cc2)C(C)(C)C)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H08 compound treatment 0.35 0.00881 0.73 0.346 0.00529 0.47 0.8485 0.9769 1940841 CBMicro_030546 CCOC(=O)c1c(C)c(C)sc1NC(=O)/C=C/c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H09 compound treatment 0.323 -0.0182 -1.51 0.328 -0.0127 -1.13 -1.8645 -0.9896 1205887 CBMicro_030547 CCCNC(=O)c1c(C)onc1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H10 compound treatment 0.339 -0.00219 -0.18 0.334 -0.00671 -0.59 -0.5492 -0.8832 1940842 CBMicro_030548 COc1ccc(NC(=O)c2cc(Cl)ccc2OC)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H11 compound treatment 0.383 0.0418 3.47 0.363 0.0223 1.98 3.851 0.9643 1424473 CBMicro_030549 COc1ccc(CCNC(=O)c2sc3cc(C)ccc3c2Cl)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H12 compound treatment 0.327 -0.0142 -1.18 0.327 -0.0137 -1.21 -1.6923 -0.9999 1940843 CBMicro_030550 CC(C)OC(=O)c1c(N)scc1c2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H13 compound treatment 0.34 -0.00119 -0.1 0.344 0.00329 0.29 0.1361 0.442 1940844 CBMicro_030551 CCN1C(=O)c2cccc3c(NC(=O)c4cc(ccc4Cl)[N+](=O)[O-])ccc1c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H14 compound treatment 0.355 0.0138 1.15 0.357 0.0163 1.44 1.8313 0.9935 1516616 CBMicro_030552 Cc1cccc(OCC(=O)Nc2cccc(Br)c2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H15 compound treatment 0.323 -0.0182 -1.51 0.334 -0.00671 -0.59 -1.4885 -0.917 1583042 CBMicro_030553 Cc1ccc(C)c(NC(=O)Cc2ccc(Br)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H16 compound treatment 0.32 -0.0212 -1.76 0.32 -0.0207 -1.84 -2.5419 -0.9998 1279810 CBMicro_030554 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H17 compound treatment 0.339 -0.00219 -0.18 0.34 -7.1E-4 -0.06 -0.1732 -0.8992 1671795 CBMicro_030555 CC(Oc1ccccc1)C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H18 compound treatment 0.349 0.00781 0.65 0.342 0.00129 0.11 0.5391 0.8192 1505496 CBMicro_030556 CC(Oc1ccccc1)C(=O)N2CCC(Cc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H19 compound treatment 0.34 -0.00119 -0.1 0.336 -0.00471 -0.42 -0.3652 -0.8513 1940845 CBMicro_030557 COc1ccc(NC(=O)Cc2ccc(Br)cc2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H20 compound treatment 0.324 -0.0172 -1.43 0.33 -0.0107 -0.95 -1.6804 -0.9803 1940846 CBMicro_030558 CCOC(=O)c1ccc(NC(=O)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H21 compound treatment 0.371 0.0298 2.47 0.374 0.0333 2.95 3.8359 0.9962 1712761 CBMicro_030559 OCCNC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H22 compound treatment 0.32 -0.0212 -1.76 0.327 -0.0137 -1.21 -2.1032 -0.9837 1940847 CBMicro_030560 Oc1ccc(/C=N/N2CCN(Cc3cccc4ccccc34)CC2)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H23 positive control 0.085 -0.256 -21.27 0.088 -0.253 -22.4 -30.8755 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 H24 positive control 0.09 -0.251 -20.85 0.095 -0.246 -21.78 -30.1433 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I01 mock treatment 0.341 -1.94E-4 -0.02 0.35 0.00929 0.82 0.5708 0.6932 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I02 mock treatment 0.346 0.00481 0.4 0.36 0.0193 1.71 1.491 0.8493 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I03 compound treatment 0.373 0.0318 2.64 0.38 0.0393 3.48 4.3293 0.9907 1940848 CBMicro_030561 C/C(=C\C(=O)c1ccc(Br)cc1)/Nc2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I04 compound treatment 0.331 -0.0102 -0.85 0.321 -0.0197 -1.75 -1.8335 -0.9447 1940849 CBMicro_030562 CCOC(=O)c1ccc(N/C=C\2/C(=O)NC(=O)N(C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I05 compound treatment 0.361 0.0198 1.64 0.362 0.0213 1.89 2.4969 0.9977 1478680 CBMicro_030563 CCOC(=O)c1c(NC(=O)C2COc3ccccc3O2)sc4CC(C)CCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I06 compound treatment 0.345 0.00381 0.32 0.337 -0.00371 -0.33 -0.009 -0.0198 1940850 CBMicro_030564 CCCCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)OC)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I07 compound treatment 0.324 -0.0172 -1.43 0.301 -0.0397 -3.52 -3.4977 -0.921 1525975 CBMicro_030565 CCOC(=O)c1cccc(NC(=O)c2ccc(Cl)cc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I08 compound treatment 0.343 0.00181 0.15 0.337 -0.00371 -0.33 -0.1264 -0.3499 1277887 CBMicro_030566 O=C(NCC1CCCO1)NC2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I09 compound treatment 0.351 0.00981 0.81 0.365 0.0243 2.15 2.0978 0.9115 1382999 CBMicro_030567 COc1ccc(OC)c(NC(=O)COc2ccc(C)c(C)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I10 compound treatment 0.371 0.0298 2.47 0.365 0.0243 2.15 3.2719 0.9976 1940851 CBMicro_030568 CCc1cccc(C)c1NC(=O)/C=C/c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I11 compound treatment 0.346 0.00481 0.4 0.352 0.0113 1.0 0.9897 0.9187 1940852 CBMicro_030569 CC(C)CC(=O)N1CCC(Cc2ccccc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I12 compound treatment 0.347 0.00581 0.48 0.361 0.0203 1.8 1.6124 0.8661 1201441 CBMicro_030570 Clc1cccc(c1)C(=O)Nc2nc3ccc(Br)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I13 compound treatment 0.348 0.00681 0.57 0.37 0.0293 2.6 2.235 0.8413 1940853 CBMicro_030571 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I14 compound treatment 0.278 -0.0632 -5.25 0.282 -0.0587 -5.2 -7.3887 -1.0 1940854 CBMicro_030572 [O-][N+](=O)c1ccc2C(=NS(=O)(=O)c2c1)N(CCOCC=C)CCOCC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I15 compound treatment 0.334 -0.00719 -0.6 0.312 -0.0287 -2.54 -2.2214 -0.85 1940855 CBMicro_030573 C=COCCNC(=O)C(=O)Nc1ccccc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I16 compound treatment 0.369 0.0278 2.31 0.345 0.00429 0.38 1.9012 0.8126 1162730 CBMicro_030574 O=C(Nc1ccc2ccccc2c1)C3CN(C(=O)C3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I17 compound treatment 0.344 0.00281 0.23 0.353 0.0123 1.09 0.9349 0.8394 1940856 CBMicro_030575 COc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)C(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I18 compound treatment 0.372 0.0308 2.56 0.374 0.0333 2.95 3.8946 0.9975 1298469 CBMicro_030576 CC(C)c1cccc(C(C)C)c1NC(=O)COc2ccc(C)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I19 compound treatment 0.352 0.0108 0.9 0.341 2.9E-4 0.03 0.6526 0.7271 1940857 CBMicro_030577 COc1ccc(cc1OC)C(=O)N(CCCCN2C(=O)c3ccccc3C2=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I20 compound treatment 0.345 0.00381 0.32 0.347 0.00629 0.56 0.6176 0.9639 1330658 CBMicro_030578 CCOC(=O)c1ccccc1NC(=O)COc2ccc(Cl)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I21 compound treatment 0.346 0.00481 0.4 0.35 0.00929 0.82 0.8643 0.9447 1331754 CBMicro_030579 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I22 compound treatment 0.351 0.00981 0.81 0.342 0.00129 0.11 0.6565 0.7986 1577058 CBMicro_030580 Brc1ccc(cc1)N(CC(=O)NCC2CCCCC2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I23 positive control 0.085 -0.256 -21.27 0.091 -0.25 -22.13 -30.6875 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 I24 positive control 0.09 -0.251 -20.85 0.095 -0.246 -21.78 -30.1433 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J01 mock treatment 0.314 -0.0272 -2.26 0.331 -0.00971 -0.86 -2.2048 -0.9126 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J02 mock treatment 0.342 8.06E-4 0.07 0.352 0.0113 1.0 0.7549 0.7527 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J03 compound treatment 0.364 0.0228 1.89 0.36 0.0193 1.71 2.5476 0.9987 1940858 CBMicro_030581 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\Nc3ccc(C)cc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J04 compound treatment 0.349 0.00781 0.65 0.347 0.00629 0.56 0.8524 0.9972 1940859 CBMicro_030582 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J05 compound treatment 0.382 0.0408 3.39 0.38 0.0393 3.48 4.8576 0.9999 1940860 CBMicro_030583 COc1cc(NC(=O)/C=C/c2ccc(C)cc2)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J06 compound treatment 0.342 8.06E-4 0.07 0.341 2.9E-4 0.03 0.0655 0.9137 1618626 CBMicro_030584 CCOC(=O)c1c(N)sc(C)c1c2ccc(OCC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J07 compound treatment 0.302 -0.0392 -3.25 0.324 -0.0167 -1.48 -3.3479 -0.9365 1940861 CBMicro_030585 Cc1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J08 compound treatment 0.345 0.00381 0.32 0.323 -0.0177 -1.57 -0.8863 -0.5536 1940862 CBMicro_030586 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)C3CC3c4ccccc4)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J09 compound treatment 0.303 -0.0382 -3.17 0.326 -0.0147 -1.3 -3.1639 -0.9229 1940863 CBMicro_030587 Cc1onc(c1C(=O)Nc2cccc(Cl)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J10 compound treatment 0.331 -0.0102 -0.85 0.339 -0.00171 -0.15 -0.7055 -0.8207 1724703 CBMicro_030588 Cc1ccc(o1)C(=O)Nc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J11 compound treatment 0.359 0.0178 1.48 0.352 0.0113 1.0 1.7528 0.9819 1940864 CBMicro_030589 CCOC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J12 compound treatment 0.341 -1.94E-4 -0.02 0.332 -0.00871 -0.77 -0.5572 -0.7217 1940865 CBMicro_030590 CC(C)OC(=O)c1c(N)scc1c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J13 compound treatment 0.32 -0.0212 -1.76 0.341 2.9E-4 0.03 -1.2259 -0.6967 1940866 CBMicro_030591 COc1ccc(OCC(=O)n2nc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J14 compound treatment 0.381 0.0398 3.3 0.377 0.0363 3.22 4.6109 0.9999 1940867 CBMicro_030592 Cc1cccc(c1)N2C(=O)C(=C(Nc3ccc(C)c(Cl)c3)C2=O)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J15 compound treatment 0.327 -0.0142 -1.18 0.339 -0.00171 -0.15 -0.9403 -0.7915 1940868 CBMicro_030593 Fc1ccc(NC(=O)Cc2ccc(Br)cc2)cc1F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J16 compound treatment 0.376 0.0348 2.89 0.369 0.0283 2.51 3.8161 0.9975 1118207 CBMicro_030594 Brc1ccc(CC(=O)N2CCN(Cc3ccccc3)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J17 compound treatment 0.332 -0.00919 -0.76 0.336 -0.00471 -0.42 -0.8348 -0.9597 1296457 CBMicro_030595 Cc1ccc(o1)C(=O)Nc2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J18 compound treatment 0.374 0.0328 2.72 0.353 0.0123 1.09 2.696 0.9191 1459910 CBMicro_030596 CCOC(=O)c1ccc(NC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J19 compound treatment 0.354 0.0128 1.06 0.366 0.0253 2.24 2.3366 0.9419 1940869 CBMicro_030597 [O-][N+](=O)c1cccc(/C=C/C(=O)N2CCN(CC2)c3cccc(Cl)c3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J20 compound treatment 0.341 -1.94E-4 -0.02 0.349 0.00829 0.73 0.5082 0.6915 1513412 CBMicro_030598 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)c(OC)c2)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J21 compound treatment 0.341 -1.94E-4 -0.02 0.347 0.00629 0.56 0.3828 0.6864 1940870 CBMicro_030599 CCOc1ccc(/C=C/C(=O)NCC=C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J22 compound treatment 0.352 0.0108 0.9 0.347 0.00629 0.56 1.0286 0.9738 1940871 CBMicro_030600 CCOC(=O)c1[nH]c2c(cc(C)cc2c1C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J23 positive control 0.085 -0.256 -21.27 0.087 -0.254 -22.48 -30.9381 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 J24 positive control 0.09 -0.251 -20.85 0.095 -0.246 -21.78 -30.1433 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K01 mock treatment 0.337 -0.00419 -0.35 0.341 2.9E-4 0.03 -0.228 -0.6531 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K02 mock treatment 0.345 0.00381 0.32 0.342 0.00129 0.11 0.3043 0.9055 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K03 compound treatment 0.351 0.00981 0.81 0.352 0.0113 1.0 1.2832 0.9948 1940872 CBMicro_030601 C/C(=C\C(=O)c1ccccc1)/Nc2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K04 compound treatment 0.349 0.00781 0.65 0.345 0.00429 0.38 0.7271 0.9677 1940873 CBMicro_030602 O=C(NCCOc1ccccc1)c2cccc(c2)C(=O)NCCOc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K05 compound treatment 0.337 -0.00419 -0.35 0.334 -0.00671 -0.59 -0.6666 -0.9675 1723991 CBMicro_030603 Cc1ccc(cc1)S(=O)(=O)Nc2cc(Sc3nc4ccccc4[nH]3)c(O)c5ccccc25 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K06 compound treatment 0.336 -0.00519 -0.43 0.315 -0.0257 -2.28 -1.916 -0.8263 1340792 CBMicro_030604 CCc1cc(=O)oc2cc(OCC(=O)N)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K07 compound treatment 0.344 0.00281 0.23 0.327 -0.0137 -1.21 -0.6944 -0.5613 1389307 CBMicro_030605 Clc1cccc(OCC(=O)NCc2ccco2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K08 compound treatment 0.403 0.0618 5.13 0.393 0.0523 4.63 6.905 0.9987 1940874 CBMicro_030606 Cc1ccc(/C=C/C(=O)Nc2ccc(F)c(c2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K09 compound treatment 0.371 0.0298 2.47 0.375 0.0343 3.04 3.8985 0.9948 1781268 CBMicro_030607 Cc1ccc(cc1NC(=O)COc2cccc(Cl)c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K10 compound treatment 0.348 0.00681 0.57 0.33 -0.0107 -0.95 -0.2716 -0.2458 1606278 CBMicro_030608 OCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K11 compound treatment 0.332 -0.00919 -0.76 0.339 -0.00171 -0.15 -0.6468 -0.8313 1135506 CBMicro_030609 Cc1ccc(o1)C(=O)Nc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K12 compound treatment 0.344 0.00281 0.23 0.349 0.00829 0.73 0.6843 0.8878 1725986 CBMicro_030610 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K13 compound treatment 0.343 0.00181 0.15 0.342 0.00129 0.11 0.1869 0.991 1940875 CBMicro_030611 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3ncccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K14 compound treatment 0.407 0.0658 5.46 0.364 0.0233 2.06 5.3225 0.9114 1940876 CBMicro_030612 Cc1ccc(Cl)cc1NC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K15 compound treatment 0.373 0.0318 2.64 0.381 0.0403 3.57 4.3919 0.989 1940877 CBMicro_030613 Clc1cccc(NC(=O)C(=O)NCc2ccccc2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K16 compound treatment 0.353 0.0118 0.98 0.345 0.00429 0.38 0.9619 0.915 1629681 CBMicro_030614 Brc1ccc(cc1)N2CC(CC2=O)C(=O)NCCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K17 compound treatment 0.345 0.00381 0.32 0.332 -0.00871 -0.77 -0.3223 -0.3865 1940878 CBMicro_030615 CC1(C)C2CCC1(C)C(=O)N(C2=O)c3nc(cs3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K18 compound treatment 0.37 0.0288 2.39 0.364 0.0233 2.06 3.1505 0.9973 1703359 CBMicro_030616 CC(C)c1ccccc1NC(=O)COc2cccc(C)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K19 compound treatment 0.389 0.0478 3.97 0.394 0.0533 4.72 6.1458 0.9963 1940879 CBMicro_030617 COc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K20 compound treatment 0.232 -0.109 -9.07 0.239 -0.102 -9.01 -12.7837 -1.0 1940880 CBMicro_030618 CCN(CC)c1ccc(/C=C\2/SC(=S)N(CC(=O)OC)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K21 compound treatment 0.34 -0.00119 -0.1 0.347 0.00629 0.56 0.3241 0.5724 1940881 CBMicro_030619 Fc1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K22 compound treatment 0.342 8.06E-4 0.07 0.34 -7.1E-4 -0.06 0.0029 0.0312 1940882 CBMicro_030620 O=C(CSc1nnc(c2ccco2)n1c3ccccc3)NCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K23 positive control 0.086 -0.255 -21.19 0.087 -0.254 -22.48 -30.8794 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 K24 positive control 0.09 -0.251 -20.85 0.098 -0.243 -21.51 -29.9553 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L01 mock treatment 0.338 -0.00319 -0.27 0.34 -7.1E-4 -0.06 -0.2319 -0.8512 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L02 mock treatment 0.344 0.00281 0.23 0.341 2.9E-4 0.03 0.1829 0.7804 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L03 compound treatment 0.331 -0.0102 -0.85 0.332 -0.00871 -0.77 -1.1442 -0.9989 1194900 CBMicro_030621 Cc1occc1C(=O)Nc2cccc(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L04 compound treatment 0.361 0.0198 1.64 0.359 0.0183 1.62 2.3089 1.0 1526245 CBMicro_030622 CCCOC(=O)c1c(N)sc2CCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L05 compound treatment 0.337 -0.00419 -0.35 0.346 0.00529 0.47 0.0853 0.1461 1478057 CBMicro_030623 C=CCn1c(SCC(=O)NCc2cccnc2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L06 compound treatment 0.324 -0.0172 -1.43 0.325 -0.0157 -1.39 -1.9938 -0.9999 1211816 CBMicro_030624 CC(C)OC(=O)c1c(N)scc1c2ccc(cc2)C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L07 compound treatment 0.35 0.00881 0.73 0.347 0.00629 0.56 0.9112 0.991 1246479 CBMicro_030625 CCOC(=O)c1c(CC)c(C)sc1NC(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L08 compound treatment 0.354 0.0128 1.06 0.361 0.0203 1.8 2.0233 0.9686 1552273 CBMicro_030626 CC(Oc1cccc(Cl)c1)C(=O)Nc2c(C)cc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L09 compound treatment 0.335 -0.00619 -0.51 0.334 -0.00671 -0.59 -0.784 -0.9974 1202056 CBMicro_030627 Cc1ccc(o1)C(=O)NCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L10 compound treatment 0.345 0.00381 0.32 0.343 0.00229 0.2 0.367 0.9771 1940883 CBMicro_030628 Clc1ccc(CC(=O)Nc2ccccc2I)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L11 compound treatment 0.355 0.0138 1.15 0.351 0.0103 0.91 1.4553 0.9936 1164966 CBMicro_030629 CCN(CC)c1ccc(NC(=O)c2ccc3ccccc3n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L12 compound treatment 0.328 -0.0132 -1.1 0.336 -0.00471 -0.42 -1.0696 -0.9125 1249448 CBMicro_030630 CC(C)OC(=O)c1c(N)scc1c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L13 compound treatment 0.326 -0.0152 -1.26 0.331 -0.00971 -0.86 -1.5004 -0.9826 1373327 CBMicro_030631 Nc1ncc(Cc2ccc(F)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L14 compound treatment 0.366 0.0248 2.06 0.354 0.0133 1.18 2.2891 0.9649 1940884 CBMicro_030632 COCCOC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L15 compound treatment 0.346 0.00481 0.4 0.341 2.9E-4 0.03 0.3003 0.7511 1940885 CBMicro_030633 CC(C)c1ccccc1NC(=O)Cc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L16 compound treatment 0.365 0.0238 1.98 0.353 0.0123 1.09 2.1677 0.9606 1940886 CBMicro_030634 Cc1onc(c1C(=O)Nc2ccc3ccccc3c2)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L17 compound treatment 0.359 0.0178 1.48 0.365 0.0243 2.15 2.5675 0.9832 1940887 CBMicro_030635 CC(=O)c1ccc(NC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L18 compound treatment 0.355 0.0138 1.15 0.354 0.0133 1.18 1.6433 0.9999 1447536 CBMicro_030636 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2cc(OCC)c(OCC)c(OCC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L19 compound treatment 0.341 -1.94E-4 -0.02 0.343 0.00229 0.2 0.1322 0.6491 1940888 CBMicro_030637 CCOC(=O)c1c(NC=O)sc2/C(=N/O)/CCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L20 compound treatment 0.319 -0.0222 -1.84 0.318 -0.0227 -2.01 -2.7259 -0.999 1614323 CBMicro_030638 CCOC(=O)c1ccc(NCc2cc(Br)ccc2O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L21 compound treatment 0.336 -0.00519 -0.43 0.331 -0.00971 -0.86 -0.9133 -0.949 1262593 CBMicro_030639 Oc1ccc(NC(=O)CC2Sc3ccccc3NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L22 compound treatment 0.341 -1.94E-4 -0.02 0.345 0.00429 0.38 0.2575 0.6766 1940889 CBMicro_030640 C/C(=C\C(=O)c1ccc(C)cc1)/Nc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L23 positive control 0.087 -0.254 -21.1 0.091 -0.25 -22.13 -30.5701 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 L24 positive control 0.09 -0.251 -20.85 0.102 -0.239 -21.15 -29.7047 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M01 mock treatment 0.339 -0.00219 -0.18 0.338 -0.00271 -0.24 -0.2986 -0.9907 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M02 mock treatment 0.338 -0.00319 -0.27 0.338 -0.00271 -0.24 -0.3573 -0.9988 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M03 compound treatment 0.367 0.0258 2.14 0.37 0.0293 2.6 3.3504 0.9955 1940890 CBMicro_030641 C/C(=C\C(=O)c1ccc(Cl)cc1)/Nc2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M04 compound treatment 0.322 -0.0192 -1.59 0.319 -0.0217 -1.92 -2.4872 -0.9956 1720386 CBMicro_030642 OC(=O)c1cccc(NCCC(=O)c2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M05 compound treatment 0.277 -0.0642 -5.33 0.285 -0.0557 -4.94 -7.2594 -0.9993 1940891 CBMicro_030643 CCN(CC)C1=C/C(=N/S(=O)(=O)c2ccccc2)/c3ccccc3C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M06 compound treatment 0.35 0.00881 0.73 0.35 0.00929 0.82 1.0991 0.9982 1940892 CBMicro_030644 CCCOc1ccc(/C=C/C(=O)Nc2c(C)cccc2C(C)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M07 compound treatment 0.337 -0.00419 -0.35 0.335 -0.00571 -0.51 -0.604 -0.9833 1473914 CBMicro_030645 CCc1cccc(C)c1NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M08 compound treatment 0.335 -0.00619 -0.51 0.334 -0.00671 -0.59 -0.784 -0.9974 1388217 CBMicro_030646 CC(C)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(C)nc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M09 compound treatment 0.338 -0.00319 -0.27 0.335 -0.00571 -0.51 -0.5453 -0.9545 1208225 CBMicro_030647 CCOc1ccccc1NC(=O)c2c(Cl)ccc(Cl)c2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M10 compound treatment 0.32 -0.0212 -1.76 0.317 -0.0237 -2.1 -2.7299 -0.9961 1940893 CBMicro_030648 [O-][N+](=O)c1cc(NC(=O)C2CC3CCC2C3)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M11 compound treatment 0.338 -0.00319 -0.27 0.333 -0.00771 -0.68 -0.6706 -0.915 1940894 CBMicro_030649 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)C(Cl)(Cl)Cl)cc2)nc(C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M12 compound treatment 0.38 0.0388 3.22 0.385 0.0443 3.93 5.0535 0.9952 1344243 CBMicro_030650 CCSc1nnc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)cc4)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M13 compound treatment 0.321 -0.0202 -1.68 0.329 -0.0117 -1.04 -1.9192 -0.9734 1376831 CBMicro_030651 COc1ccc(C)cc1NC(=O)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M14 compound treatment 0.378 0.0368 3.06 0.376 0.0353 3.13 4.3721 0.9999 1781391 CBMicro_030652 [O-][N+](=O)c1ccc2nc(SCc3nc4ccccc4[nH]3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M15 compound treatment 0.355 0.0138 1.15 0.359 0.0183 1.62 1.9566 0.9856 1940895 CBMicro_030653 Clc1cccc(NC(=O)C(=O)NCCc2ccccc2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M16 compound treatment 0.333 -0.00819 -0.68 0.339 -0.00171 -0.15 -0.5881 -0.8439 1181247 CBMicro_030654 COC(=O)c1ccccc1NC(=O)C2CN(C(=O)C2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M17 compound treatment 0.397 0.0558 4.63 0.389 0.0483 4.28 6.3021 0.9992 1741470 CBMicro_030655 COc1cc(cc(OC)c1OC)C(=O)Nc2nc3ccc(Br)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M18 compound treatment 0.376 0.0348 2.89 0.361 0.0203 1.8 3.3147 0.974 1423320 CBMicro_030656 Cc1ccc(C)c(NC(=O)COc2cccc(C)c2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M19 compound treatment 0.335 -0.00619 -0.51 0.329 -0.0117 -1.04 -1.0974 -0.9475 1297033 CBMicro_030657 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M20 compound treatment 0.384 0.0428 3.55 0.386 0.0453 4.01 5.351 0.9982 1144307 CBMicro_030658 COC(=O)c1ccc(NC(=O)COc2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M21 compound treatment 0.389 0.0478 3.97 0.362 0.0213 1.89 4.1406 0.9422 1940896 CBMicro_030659 COCCOC(=O)c1ccc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M22 compound treatment 0.352 0.0108 0.9 0.355 0.0143 1.27 1.5299 0.9857 1940897 CBMicro_030660 Cc1ccc(NC(=O)C(=O)NCc2ccco2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M23 positive control 0.087 -0.254 -21.1 0.089 -0.252 -22.31 -30.6954 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 M24 positive control 0.092 -0.249 -20.69 0.095 -0.246 -21.78 -30.0259 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N01 mock treatment 0.345 0.00381 0.32 0.339 -0.00171 -0.15 0.1163 0.3319 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N02 mock treatment 0.345 0.00381 0.32 0.348 0.00729 0.65 0.6803 0.9459 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N03 compound treatment 0.337 -0.00419 -0.35 0.337 -0.00371 -0.33 -0.4786 -0.9996 1533078 CBMicro_030661 COc1ccc(CSc2nc3ccc(Br)cc3c(=O)n2c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N04 compound treatment 0.351 0.00981 0.81 0.347 0.00629 0.56 0.9699 0.9829 1705161 CBMicro_030662 COC(=O)c1c(N)sc(C)c1c2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N05 compound treatment 0.372 0.0308 2.56 0.379 0.0383 3.39 4.2079 0.9903 1940898 CBMicro_030663 C=CCn1c(SCC(=O)NCc2ccco2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N06 compound treatment 0.351 0.00981 0.81 0.348 0.00729 0.65 1.0325 0.9934 1458107 CBMicro_030664 CCOC(=O)c1c(N)scc1c2ccc(OCC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N07 compound treatment 0.316 -0.0252 -2.09 0.331 -0.00971 -0.86 -2.0874 -0.923 1505148 CBMicro_030665 CC(C)OC(=O)c1sc(NC(=O)C)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N08 compound treatment 0.343 0.00181 0.15 0.337 -0.00371 -0.33 -0.1264 -0.3499 1940899 CBMicro_030666 FC(F)(F)C(=O)Nc1ccc2OCCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N09 compound treatment 0.353 0.0118 0.98 0.344 0.00329 0.29 0.8993 0.8794 1333799 CBMicro_030667 COc1ccc(CNC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N10 compound treatment 0.358 0.0168 1.4 0.354 0.0133 1.18 1.8194 0.9964 1940900 CBMicro_030668 CCSc1nnc(NC(=O)c2ccc(Br)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N11 compound treatment 0.352 0.0108 0.9 0.348 0.00729 0.65 1.0912 0.987 1388724 CBMicro_030669 CC(=O)Nc1nc2cc3sc(NC(=O)C)nc3cc2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N12 compound treatment 0.323 -0.0182 -1.51 0.329 -0.0117 -1.04 -1.8018 -0.9832 1633972 CBMicro_030670 CCOC(=O)c1c(N)sc2CC(CCc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N13 compound treatment 0.346 0.00481 0.4 0.341 2.9E-4 0.03 0.3003 0.7511 1453144 CBMicro_030671 CC(C)NC(=O)C1(CC2CC3C1)CC(C2)(C3)C(=O)NC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N14 compound treatment 0.4 0.0588 4.88 0.39 0.0493 4.37 6.5409 0.9985 1144784 CBMicro_030672 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4Cc6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N15 compound treatment 0.336 -0.00519 -0.43 0.333 -0.00771 -0.68 -0.788 -0.9754 1940901 CBMicro_030673 Cc1ccc(o1)C(=O)Nc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N16 compound treatment 0.355 0.0138 1.15 0.358 0.0173 1.53 1.894 0.9898 1785981 CBMicro_030674 COc1ccc(cc1NC(=O)Cc2ccc(Cl)cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N17 compound treatment 0.356 0.0148 1.23 0.354 0.0133 1.18 1.702 0.9998 1296664 CBMicro_030675 COC(=O)c1ccc(C(=O)OC)c(NC(=O)Cc2ccc(Cl)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N18 compound treatment 0.357 0.0158 1.31 0.358 0.0173 1.53 2.0114 0.997 1194541 CBMicro_030676 CCOc1ccc(NC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N19 compound treatment 0.347 0.00581 0.48 0.344 0.00329 0.29 0.547 0.971 1940902 CBMicro_030677 FC(F)(F)c1ccccc1NC(=O)Cc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N20 compound treatment 0.347 0.00581 0.48 0.343 0.00229 0.2 0.4844 0.9261 1182320 CBMicro_030678 COc1ccc(NC(=O)Cc2ccc(Br)cc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N21 compound treatment 0.343 0.00181 0.15 0.346 0.00529 0.47 0.4376 0.8889 1785971 CBMicro_030679 CC(Oc1ccccc1)C(=O)Nc2cc(ccc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N22 compound treatment 0.324 -0.0172 -1.43 0.322 -0.0187 -1.66 -2.1818 -0.9972 1940903 CBMicro_030680 CCOc1ccccc1NC(=O)CSCc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N23 positive control 0.087 -0.254 -21.1 0.092 -0.249 -22.04 -30.5074 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 N24 positive control 0.092 -0.249 -20.69 0.105 -0.236 -20.89 -29.3993 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O01 mock treatment 0.342 8.06E-4 0.07 0.347 0.00629 0.56 0.4415 0.7864 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O02 mock treatment 0.344 0.00281 0.23 0.35 0.00929 0.82 0.7469 0.8729 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O03 compound treatment 0.342 8.06E-4 0.07 0.338 -0.00271 -0.24 -0.1225 -0.4912 1126756 CBMicro_030681 CC1=NN(C(=O)OC(C)(C)C)C(O)(C1)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O04 compound treatment 0.339 -0.00219 -0.18 0.341 2.9E-4 0.03 -0.1106 -0.6012 1940904 CBMicro_030682 CCOC(=O)c1c(NC(=O)/C=C/c2cccs2)sc3CCCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O05 compound treatment 0.337 -0.00419 -0.35 0.345 0.00429 0.38 0.0227 0.044 1274231 CBMicro_030683 CCOC(=O)c1c(NC(=O)C(C)N2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O06 compound treatment 0.35 0.00881 0.73 0.354 0.0133 1.18 1.3498 0.9737 1157271 CBMicro_030684 C=CCn1c(SCC#C)nc2sc3CCCCc3c2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O07 compound treatment 0.342 8.06E-4 0.07 0.334 -0.00671 -0.59 -0.3731 -0.6236 1739927 CBMicro_030685 O=C(NC1CCCCC1)C(NC(=O)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O08 compound treatment 0.333 -0.00819 -0.68 0.341 2.9E-4 0.03 -0.4628 -0.6799 1940905 CBMicro_030686 CC(C)(C)c1ccc(/C=C/C(=O)n2cccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O09 compound treatment 0.352 0.0108 0.9 0.352 0.0113 1.0 1.3419 0.9985 1525452 CBMicro_030687 CC(C)c1ccc(OCC(=O)Nc2ccc(F)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O10 compound treatment 0.386 0.0448 3.72 0.385 0.0443 3.93 5.4057 0.9996 1940906 CBMicro_030688 C/C(=N\NC(=O)c1ccccc1[N+](=O)[O-])/c2c(O)cc(C)oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O11 compound treatment 0.331 -0.0102 -0.85 0.336 -0.00471 -0.42 -0.8935 -0.9469 1333185 CBMicro_030689 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O12 compound treatment 0.359 0.0178 1.48 0.353 0.0123 1.09 1.8155 0.9887 1234110 CBMicro_030690 COC(=O)c1sc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)c(C#N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O13 compound treatment 0.338 -0.00319 -0.27 0.339 -0.00171 -0.15 -0.2946 -0.9648 1411458 CBMicro_030691 Fc1ccccc1C(=O)Nc2ncccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O14 compound treatment 0.34 -0.00119 -0.1 0.334 -0.00671 -0.59 -0.4905 -0.8137 1940907 CBMicro_030692 Fc1ccc(NC(=O)C(=O)NCCOC=C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O15 compound treatment 0.337 -0.00419 -0.35 0.339 -0.00171 -0.15 -0.3533 -0.9305 1652957 CBMicro_030693 Cc1nnc(SCC(=O)NCC(=O)c2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O16 compound treatment 0.341 -1.94E-4 -0.02 0.338 -0.00271 -0.24 -0.1812 -0.7527 1419748 CBMicro_030694 Cc1ccccc1NC(=O)C2CN(C(=O)C2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O17 compound treatment 0.35 0.00881 0.73 0.348 0.00729 0.65 0.9738 0.9981 1736824 CBMicro_030695 Clc1ccc(cc1Cl)C(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O18 compound treatment 0.334 -0.00719 -0.6 0.335 -0.00571 -0.51 -0.7801 -0.9966 1940908 CBMicro_030696 COC(=O)c1cccc(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O19 compound treatment 0.343 0.00181 0.15 0.338 -0.00271 -0.24 -0.0638 -0.2252 1296641 CBMicro_030697 Cc1c(OCc2ccc(Cl)cc2)ccc3c4CCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O20 compound treatment 0.339 -0.00219 -0.18 0.35 0.00929 0.82 0.4534 0.5377 1940909 CBMicro_030698 Clc1ccc(NC(=O)CCCOc2ccccc2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O21 compound treatment 0.347 0.00581 0.48 0.352 0.0113 1.0 1.0484 0.9439 1668828 CBMicro_030699 O=C(CSc1nc2ccccc2o1)Nc3nc4CCCCc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O22 compound treatment 0.343 0.00181 0.15 0.343 0.00229 0.2 0.2496 0.9889 1940910 CBMicro_030700 CC(C)c1ccc(C)cc1OCCNC(=O)c2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O23 positive control 0.086 -0.255 -21.19 0.091 -0.25 -22.13 -30.6288 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 O24 positive control 0.092 -0.249 -20.69 0.096 -0.245 -21.69 -29.9632 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P01 mock treatment 0.343 0.00181 0.15 0.339 -0.00171 -0.15 -0.0011 -0.0051 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P02 mock treatment 0.344 0.00281 0.23 0.344 0.00329 0.29 0.3709 0.9938 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P03 compound treatment 0.348 0.00681 0.57 0.337 -0.00371 -0.33 0.1671 0.2556 1410966 CBMicro_030701 Cc1occc1C(=O)Nc2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P04 compound treatment 0.346 0.00481 0.4 0.338 -0.00271 -0.24 0.1124 0.2412 1940911 CBMicro_030702 COC(=O)c1c(N)sc(C)c1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P05 compound treatment 0.327 -0.0142 -1.18 0.346 0.00529 0.47 -0.5017 -0.3956 1940912 CBMicro_030703 C=CCn1c(SCC(=O)NCCCN2CCOCC2)nc3sc4CCCCc4c3c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P06 compound treatment 0.33 -0.0112 -0.93 0.335 -0.00571 -0.51 -1.0149 -0.9592 1276284 CBMicro_030704 CCCOC(=O)c1c(N)scc1c2cc(C)ccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P07 compound treatment 0.377 0.0358 2.97 0.369 0.0283 2.51 3.8748 0.9964 1165000 CBMicro_030705 Cc1ccc(Nc2ncnc3ccc(Br)cc23)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P08 compound treatment 0.358 0.0168 1.4 0.359 0.0183 1.62 2.1328 0.9972 1406321 CBMicro_030706 COc1cc(cc(OC)c1OC)C(=O)Nc2nc(C)c(C)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P09 compound treatment 0.348 0.00681 0.57 0.348 0.00729 0.65 0.8564 0.9978 1549009 CBMicro_030707 Fc1ccc(cc1)N2CCN(CC2)C(=O)Cc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P10 compound treatment 0.358 0.0168 1.4 0.359 0.0183 1.62 2.1328 0.9972 1214468 CBMicro_030708 COc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccc(C)n4)c5ccccc5n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P11 compound treatment 0.37 0.0288 2.39 0.374 0.0333 2.95 3.7772 0.9946 1864141 CBMicro_030709 Cc1ccc(OCC(=O)Nc2cc(ccc2C)[N+](=O)[O-])c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P12 compound treatment 0.331 -0.0102 -0.85 0.334 -0.00671 -0.59 -1.0189 -0.9851 1940913 CBMicro_030710 COC(=O)c1sc2ccccc2c1N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P13 compound treatment 0.372 0.0308 2.56 0.373 0.0323 2.86 3.8319 0.9984 1940914 CBMicro_030711 CCCCOc1ccc2nsnc2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P14 compound treatment 0.345 0.00381 0.32 0.348 0.00729 0.65 0.6803 0.9459 1311066 CBMicro_030712 CCc1cccc(C)c1NC(=O)COc2ccc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P15 compound treatment 0.374 0.0328 2.72 0.36 0.0193 1.71 3.1347 0.9748 1940915 CBMicro_030713 Cc1ccc(CNC(=O)Cc2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P16 compound treatment 0.338 -0.00319 -0.27 0.341 2.9E-4 0.03 -0.1693 -0.6355 1475790 CBMicro_030714 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3ccc(F)cc3)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P17 compound treatment 0.36 0.0188 1.56 0.354 0.0133 1.18 1.9368 0.9903 1372427 CBMicro_030715 COc1ccc(CNC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P18 compound treatment 0.337 -0.00419 -0.35 0.334 -0.00671 -0.59 -0.6666 -0.9675 1633417 CBMicro_030716 Brc1cccc(c1)C(=O)NCCc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P19 compound treatment 0.353 0.0118 0.98 0.349 0.00829 0.73 1.2126 0.9899 1785983 CBMicro_030717 CCC(C(=O)Nc1cc(ccc1OC)[N+](=O)[O-])c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P20 compound treatment 0.332 -0.00919 -0.76 0.332 -0.00871 -0.77 -1.0855 -1.0 1543423 CBMicro_030718 COc1ccc(Cl)cc1NC(=O)Cc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P21 compound treatment 0.352 0.0108 0.9 0.342 0.00129 0.11 0.7152 0.7908 1307693 CBMicro_030719 Cc1occc1C(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P22 compound treatment 0.329 -0.0122 -1.01 0.337 -0.00371 -0.33 -0.9483 -0.8909 1940916 CBMicro_030720 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P23 positive control 0.089 -0.252 -20.94 0.096 -0.245 -21.69 -30.1393 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.781 P24 positive control 0.094 -0.247 -20.52 0.095 -0.246 -21.78 -29.9085 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A01 mock treatment 0.339 -0.0031 -0.26 0.338 -0.00384 -0.34 -0.4223 -0.9905 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A02 mock treatment 0.341 -0.0011 -0.09 0.358 0.0162 1.43 0.9484 0.6608 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A03 compound treatment 0.332 -0.0101 -0.84 0.333 -0.00884 -0.78 -1.1466 -0.9994 1940917 CBMicro_030721 NC(=O)c1cccc2/C(=N/O)/c3ccccc3-c21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A04 compound treatment 0.333 -0.0091 -0.76 0.338 -0.00384 -0.34 -0.7746 -0.9351 1940918 CBMicro_030722 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4Sc5ccc(cc35)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A05 compound treatment 0.335 -0.0071 -0.59 0.338 -0.00384 -0.34 -0.6572 -0.9659 1940919 CBMicro_030723 Fc1cccc(c1)C(=O)Nc2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A06 compound treatment 0.328 -0.0141 -1.17 0.332 -0.00984 -0.87 -1.4441 -0.9895 1940920 CBMicro_030724 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A07 compound treatment 0.408 0.0659 5.47 0.41 0.0682 6.04 8.1401 0.9988 1398127 CBMicro_030725 COC(=O)c1ccc(NC(=O)CC2Nc3ccccc3NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A08 compound treatment 0.4 0.0579 4.81 0.375 0.0332 2.94 5.4772 0.9721 1040566 CBMicro_030726 [O-][N+](=O)c1cccc(c1)C2CC(=NN2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A09 compound treatment 0.322 -0.0201 -1.67 0.323 -0.0188 -1.67 -2.3603 -1.0 1940921 CBMicro_030727 COc1ccc(/C=N/n2cn[nH]c2=S)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A10 compound treatment 0.328 -0.0141 -1.17 0.326 -0.0158 -1.4 -1.8201 -0.9959 1940922 CBMicro_030728 Cc1cc(Cl)c(OCCN2CCCCC2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A11 compound treatment 0.348 0.0059 0.49 0.348 0.00616 0.55 0.7326 0.9985 1940923 CBMicro_030729 CC(=O)c1ccc(cc1)N2C(=O)C3CCC(C)(C2=O)C3(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A12 compound treatment 0.369 0.0269 2.23 0.363 0.0212 1.88 2.9054 0.9962 1940924 CBMicro_030730 COc1ccccc1NCN2C(=O)S/C(=C/c3ccc(OC)c(OC)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A13 compound treatment 0.35 0.0079 0.66 0.349 0.00716 0.63 0.9127 0.9999 1940925 CBMicro_030731 Cc1onc(c1C(=O)Nc2nc(cs2)c3ccc4ccccc4c3)c5c(Cl)cccc5Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A14 compound treatment 0.364 0.0219 1.82 0.38 0.0382 3.38 3.6772 0.9577 1940926 CBMicro_030732 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(OC)cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A15 compound treatment 0.342 -9.68E-5 -0.01 0.333 -0.00884 -0.78 -0.5596 -0.7143 1940927 CBMicro_030733 CCCCN(CN1C(=O)C2CC=C(Cl)CC2C1=O)CN3C(=O)C4CC=C(Cl)CC4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A16 compound treatment 0.341 -0.0011 -0.09 0.337 -0.00484 -0.43 -0.3676 -0.8386 1500386 CBMicro_030734 CC(=O)Nc1ccccc1C(=O)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A17 compound treatment 0.429 0.0869 7.21 0.445 0.103 9.14 11.5661 0.9931 1940928 CBMicro_030735 COc1ccc(/C=C/C(=O)Nc2nc(cs2)c3ccc(Cl)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A18 compound treatment 0.335 -0.0071 -0.59 0.336 -0.00584 -0.52 -0.7825 -0.9979 1343356 CBMicro_030736 CC1(C)NC(=O)N(CC(O)COc2cccc3ccccc23)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A19 compound treatment 0.338 -0.0041 -0.34 0.336 -0.00584 -0.52 -0.6064 -0.9793 1296984 CBMicro_030737 Cc1cccc(NC(=O)c2ccncc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A20 compound treatment 0.34 -0.0021 -0.17 0.339 -0.00284 -0.25 -0.301 -0.9838 1155304 CBMicro_030738 COc1ccccc1N2C(=O)CC(Nc3ccc(C)cc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A21 compound treatment 0.329 -0.0131 -1.09 0.331 -0.0108 -0.96 -1.448 -0.9981 1534980 CBMicro_030739 COc1ccc2C(Nc3cc(C)ccn3)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A22 compound treatment 0.374 0.0319 2.65 0.363 0.0212 1.88 3.1989 0.9857 1544233 CBMicro_030740 CCCOc1ccc(cc1)N2C(=O)CC(N(CCc3ccccc3)C(=S)Nc4ccccc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A23 positive control 0.085 -0.257 -21.34 0.084 -0.258 -22.85 -31.2499 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 A24 positive control 0.087 -0.255 -21.18 0.087 -0.255 -22.58 -30.9445 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B01 mock treatment 0.331 -0.0111 -0.92 0.333 -0.00884 -0.78 -1.2053 -0.9967 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B02 mock treatment 0.343 9.03E-4 0.07 0.337 -0.00484 -0.43 -0.2502 -0.5747 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B03 compound treatment 0.337 -0.0051 -0.42 0.334 -0.00784 -0.69 -0.7904 -0.9717 1940929 CBMicro_030741 OC(CNC(=O)C(F)(F)C(F)(F)F)CNC(=O)C(F)(F)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B04 compound treatment 0.337 -0.0051 -0.42 0.337 -0.00484 -0.43 -0.6024 -1.0 1671735 CBMicro_030742 COC(C)(C)CNS(=O)(=O)c1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B05 compound treatment 0.347 0.0049 0.41 0.345 0.00316 0.28 0.4859 0.9834 1940930 CBMicro_030743 [O-][N+](=O)c1cccc(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B06 compound treatment 0.323 -0.0191 -1.59 0.318 -0.0238 -2.11 -2.6149 -0.99 1940931 CBMicro_030744 CC(C1CC1)N(Cc2ccccc2)C(=O)Nc3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B07 compound treatment 0.377 0.0349 2.9 0.361 0.0192 1.7 3.2497 0.9676 1940932 CBMicro_030745 Clc1cccc(CC2S/C(=N\N=C\c3ccccc3)/NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B08 compound treatment 0.366 0.0239 1.98 0.372 0.0302 2.67 3.2933 0.9892 1940933 CBMicro_030746 CCOc1ccc(NC(=O)c2ccc(OC)c(OC)c2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B09 compound treatment 0.36 0.0179 1.49 0.347 0.00516 0.46 1.3744 0.8838 1940934 CBMicro_030747 Oc1c(CC=C)cccc1/C=N/N=C\2/NC(=O)CS2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B10 compound treatment 0.33 -0.0121 -1.0 0.323 -0.0188 -1.67 -1.8907 -0.9704 1940935 CBMicro_030748 [O-][N+](=O)c1cccc(c1)N(Cc2ccccc2)C(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B11 compound treatment 0.34 -0.0021 -0.17 0.335 -0.00684 -0.61 -0.5516 -0.8748 1940936 CBMicro_030749 OC(=O)C(NC(=O)c1ccc(cc1)[N+](=O)[O-])C2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B12 compound treatment 0.074 -0.268 -22.26 0.072 -0.27 -23.91 -32.6476 -0.9994 1940937 CBMicro_030750 O=C1C=CC(=O)N1c2ccc(cc2)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B13 compound treatment 0.334 -0.0081 -0.67 0.331 -0.0108 -0.96 -1.1545 -0.9848 1319239 CBMicro_030751 Cc1cc(NC(=O)c2ccc(Br)o2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B14 compound treatment 0.338 -0.0041 -0.34 0.335 -0.00684 -0.61 -0.669 -0.9627 1940938 CBMicro_030752 COc1ccc(/C=N/N=C\2/NC(=O)C(CC(=O)O)S2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B15 compound treatment 0.366 0.0239 1.98 0.329 -0.0128 -1.14 0.5987 0.2617 1688639 CBMicro_030753 Clc1ccc(cc1)N2C(=O)CC(N(Cc3ccc4OCOc4c3)C(=S)Nc5ccccc5)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B16 compound treatment 0.357 0.0149 1.24 0.352 0.0102 0.9 1.5116 0.9878 1022685 CBMicro_030754 Clc1ccc(cc1)S(=O)(=O)NC2c3ccccc3Oc4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B17 compound treatment 0.337 -0.0051 -0.42 0.334 -0.00784 -0.69 -0.7904 -0.9717 1370246 CBMicro_030755 O=C(CC1OC(=O)c2ccccc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B18 compound treatment 0.335 -0.0071 -0.59 0.33 -0.0118 -1.05 -1.1585 -0.9628 1940939 CBMicro_030756 CCOC(=O)c1sc(NC(=O)COc2cc(Cl)ccc2Cl)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B19 compound treatment 0.371 0.0289 2.4 0.372 0.0302 2.67 3.5868 0.9986 1940940 CBMicro_030757 COc1ccc(cc1)c2ccc(/C=C/C(=O)c3ccc(C)cc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B20 compound treatment 0.357 0.0149 1.24 0.353 0.0112 0.99 1.5743 0.9938 1185459 CBMicro_030758 CCOC(=O)c1sc(NC(=O)c2cc(OC)cc(OC)c2)c(C(=O)N)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B21 compound treatment 0.335 -0.0071 -0.59 0.331 -0.0108 -0.96 -1.0958 -0.9725 1940941 CBMicro_030759 [O-][N+](=O)c1cccc(/C=C/C(=O)NCCCn2ccnc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B22 compound treatment 0.344 0.0019 0.16 0.339 -0.00284 -0.25 -0.0662 -0.2227 1498658 CBMicro_030760 OCCN(CCO)S(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)N(CCO)CCO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B23 positive control 0.086 -0.256 -21.26 0.085 -0.257 -22.76 -31.1285 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 B24 positive control 0.086 -0.256 -21.26 0.085 -0.257 -22.76 -31.1285 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C01 mock treatment 0.339 -0.0031 -0.26 0.339 -0.00284 -0.25 -0.3597 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C02 mock treatment 0.342 -9.68E-5 -0.01 0.348 0.00616 0.55 0.3804 0.6966 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C03 compound treatment 0.347 0.0049 0.41 0.341 -8.39E-4 -0.07 0.2353 0.5686 1171664 CBMicro_030761 Clc1ccc(NC(=O)c2ccc3ccccc3c2)cc1c4nc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C04 compound treatment 0.344 0.0019 0.16 0.334 -0.00784 -0.69 -0.3795 -0.5327 1940942 CBMicro_030762 CCCNC1=CC(=O)C(=CC1=O)NCCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C05 compound treatment 0.342 -9.68E-5 -0.01 0.341 -8.39E-4 -0.07 -0.0582 -0.779 1524685 CBMicro_030763 Cc1cc(C)nc(NC(=O)c2ccc(F)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C06 compound treatment 0.336 -0.0061 -0.51 0.329 -0.0128 -1.14 -1.1624 -0.9335 1138374 CBMicro_030764 Clc1cc(Cl)c2OC3(CCCCC3=Cc2c1)N4CCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C07 compound treatment 0.336 -0.0061 -0.51 0.33 -0.0118 -1.05 -1.0998 -0.9441 1383434 CBMicro_030765 COc1ccc(Cl)cc1NC(=O)CC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C08 compound treatment 0.367 0.0249 2.07 0.36 0.0182 1.61 2.6 0.9923 1666848 CBMicro_030766 COc1ccc(CCNC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C09 compound treatment 0.347 0.0049 0.41 0.352 0.0102 0.9 0.9246 0.9356 1155500 CBMicro_030767 COc1ccc(COc2ccc3c(C)cc(=O)oc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C10 compound treatment 0.347 0.0049 0.41 0.349 0.00716 0.63 0.7366 0.977 1739342 CBMicro_030768 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4cc(C)c(C)cc4C(=CC3(C)C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C11 compound treatment 0.329 -0.0131 -1.09 0.326 -0.0158 -1.4 -1.7614 -0.992 1173689 CBMicro_030769 CC1=C(C(NC(=S)N1)c2ccc(C)o2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C12 compound treatment 0.34 -0.0021 -0.17 0.336 -0.00584 -0.52 -0.489 -0.8957 1363014 CBMicro_030770 OC1(N(C(=O)c2ccccc21)c3cccc(F)c3)c4ncc[nH]4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C13 compound treatment 0.348 0.0059 0.49 0.347 0.00516 0.46 0.67 0.9994 1728109 CBMicro_030771 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccn3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C14 compound treatment 0.341 -0.0011 -0.09 0.343 0.00116 0.1 0.0084 0.061 1940943 CBMicro_030772 CCN1C(=O)/C(=C/c2cccc(Cl)c2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C15 compound treatment 0.336 -0.0061 -0.51 0.331 -0.0108 -0.96 -1.0371 -0.9552 1940944 CBMicro_030773 CCOC(=O)CNC(=O)C(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C16 compound treatment 0.34 -0.0021 -0.17 0.338 -0.00384 -0.34 -0.3636 -0.9516 1192458 CBMicro_030774 Cc1ccc(Nc2cc(=O)n(C)c(=O)[nH]2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C17 compound treatment 0.376 0.0339 2.81 0.369 0.0272 2.41 3.6923 0.997 1940945 CBMicro_030775 CCSc1nc2ccccc2n1C(=O)/C=C/c3ccc(OC)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C18 compound treatment 0.339 -0.0031 -0.26 0.338 -0.00384 -0.34 -0.4223 -0.9905 1304085 CBMicro_030776 CCC(Sc1n[nH]c(=O)[nH]c1=O)C(=O)OCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C19 compound treatment 0.391 0.0489 4.06 0.396 0.0542 4.8 6.2648 0.9965 1083308 CBMicro_030777 Clc1ccc(NC(=O)C(c2ccccc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C20 compound treatment 0.343 9.03E-4 0.07 0.341 -8.39E-4 -0.07 5.0E-4 0.0044 1940946 CBMicro_030778 CCOCCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C21 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1483084 CBMicro_030779 Cc1ccccc1CN2CCN(Cc3ccncc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C22 compound treatment 0.347 0.0049 0.41 0.338 -0.00384 -0.34 0.0473 0.0891 1325271 CBMicro_030780 Cc1cc(=O)oc2cc(OCC(=O)Nc3sc4CCCc4c3C(=O)N)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C23 positive control 0.085 -0.257 -21.34 0.083 -0.259 -22.94 -31.3126 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 C24 positive control 0.091 -0.251 -20.85 0.088 -0.254 -22.5 -30.647 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D01 mock treatment 0.344 0.0019 0.16 0.345 0.00316 0.28 0.3098 0.9633 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D02 mock treatment 0.344 0.0019 0.16 0.344 0.00216 0.19 0.2472 0.9954 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D03 compound treatment 0.349 0.0069 0.57 0.343 0.00116 0.1 0.478 0.821 1173795 CBMicro_030781 COc1ccc(cc1OC)C(=O)NC2CCC(CC3CCC(CC3)NC(=O)c4ccc(OC)c(OC)c4)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D04 compound treatment 0.342 -9.68E-5 -0.01 0.337 -0.00484 -0.43 -0.3089 -0.7202 1726780 CBMicro_030782 Fc1cccc(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D05 compound treatment 0.331 -0.0111 -0.92 0.328 -0.0138 -1.23 -1.5186 -0.9901 1940947 CBMicro_030783 Cc1ccc(NC(=O)c2cccc(F)c2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D06 compound treatment 0.324 -0.0181 -1.5 0.321 -0.0208 -1.85 -2.3682 -0.9948 1475402 CBMicro_030784 CC(C1CC1)N(C(=O)Nc2ccccc2Cl)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D07 compound treatment 0.337 -0.0051 -0.42 0.333 -0.00884 -0.78 -0.8531 -0.9582 1940948 CBMicro_030785 [O-][N+](=O)OC1(CC2CC3C1)CC(C2)(C3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D08 compound treatment 0.346 0.0039 0.32 0.344 0.00216 0.19 0.3646 0.9685 1300544 CBMicro_030786 Fc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3cccc(F)c3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D09 compound treatment 0.334 -0.0081 -0.67 0.327 -0.0148 -1.32 -1.4052 -0.9515 1455731 CBMicro_030787 Cc1cccc(N2C(=O)CC(Sc3ccccc3C(=O)O)C2=O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D10 compound treatment 0.334 -0.0081 -0.67 0.33 -0.0118 -1.05 -1.2172 -0.9768 1940949 CBMicro_030788 Brc1cccc(/C=N/NC(=O)c2cnccn2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D11 compound treatment 0.358 0.0159 1.32 0.344 0.00216 0.19 1.069 0.8013 1110793 CBMicro_030789 Cc1ccc(NC(=O)C(c2ccccc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D12 compound treatment 0.53 0.188 15.6 0.507 0.165 14.64 21.3804 0.9995 1940950 CBMicro_030790 OC(=O)/C(=C/c1ccc(o1)c2cccc(c2)C(F)(F)F)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D13 compound treatment 0.337 -0.0051 -0.42 0.333 -0.00884 -0.78 -0.8531 -0.9582 1940951 CBMicro_030791 CCCNC(=O)C(F)(F)C(F)(F)C(=O)NCCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D14 compound treatment 0.341 -0.0011 -0.09 0.338 -0.00384 -0.34 -0.3049 -0.8659 1940952 CBMicro_030792 COc1ccc(cc1)C(=O)SC2=NCCS2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D15 compound treatment 0.437 0.0949 7.88 0.444 0.102 9.05 11.9731 0.9976 1940953 CBMicro_030793 CC(N1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D16 compound treatment 0.366 0.0239 1.98 0.346 0.00416 0.37 1.664 0.8244 1471524 CBMicro_030794 C(Sc1nnc2c3ccccc3[nH]c2n1)c4cccc(Oc5ccccc5)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D17 compound treatment 0.363 0.0209 1.74 0.356 0.0142 1.26 2.1145 0.9873 1152028 CBMicro_030795 CCc1ccccc1NC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D18 compound treatment 0.338 -0.0041 -0.34 0.334 -0.00784 -0.69 -0.7317 -0.946 1940954 CBMicro_030796 CCOC(=O)c1c(C)c(C)sc1NC(=S)NC(=O)c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D19 compound treatment 0.353 0.0109 0.91 0.35 0.00816 0.72 1.1515 0.9938 1346209 CBMicro_030797 Cc1cc(NC(=O)CCc2ccccc2)ccc1NC(=O)CCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D20 compound treatment 0.362 0.0199 1.65 0.361 0.0192 1.7 2.3691 0.9999 1593751 CBMicro_030798 COC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D21 compound treatment 0.332 -0.0101 -0.84 0.333 -0.00884 -0.78 -1.1466 -0.9994 1940955 CBMicro_030799 FC(F)(F)c1ccccc1NC(=O)CC2SC(=N)NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D22 compound treatment 0.341 -0.0011 -0.09 0.338 -0.00384 -0.34 -0.3049 -0.8659 1596966 CBMicro_030800 COC(=O)c1c(NC(=O)c2ccc(OC)c(OC)c2)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D23 positive control 0.085 -0.257 -21.34 0.083 -0.259 -22.94 -31.3126 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 D24 positive control 0.092 -0.25 -20.76 0.088 -0.254 -22.5 -30.5883 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E01 mock treatment 0.329 -0.0131 -1.09 0.334 -0.00784 -0.69 -1.26 -0.9766 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E02 mock treatment 0.344 0.0019 0.16 0.348 0.00616 0.55 0.4978 0.8758 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E03 compound treatment 0.341 -0.0011 -0.09 0.335 -0.00684 -0.61 -0.4929 -0.8043 1596395 CBMicro_030801 Cc1ccc(cc1)S(=O)(=O)N(CC=C)c2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E04 compound treatment 0.338 -0.0041 -0.34 0.332 -0.00984 -0.87 -0.857 -0.9157 1940956 CBMicro_030802 COc1ccc(cc1NC(=O)c2c(Cl)cccc2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E05 compound treatment 0.344 0.0019 0.16 0.336 -0.00584 -0.52 -0.2542 -0.4698 1391665 CBMicro_030803 COc1ccc(NC(=O)c2cccc(F)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E06 compound treatment 0.362 0.0199 1.65 0.337 -0.00484 -0.43 0.8652 0.5068 1282994 CBMicro_030804 O=S(=O)(N1CCCCC1)c2ccc(NC(=S)Nc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E07 compound treatment 0.333 -0.0091 -0.76 0.33 -0.0118 -1.05 -1.2759 -0.987 1619333 CBMicro_030805 CCOC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(C)nc(C)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E08 compound treatment 0.348 0.0059 0.49 0.339 -0.00284 -0.25 0.1687 0.3061 1940957 CBMicro_030806 CCCCc1ccc(CCCCC(=O)O)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E09 compound treatment 0.335 -0.0071 -0.59 0.335 -0.00684 -0.61 -0.8452 -0.9999 1648841 CBMicro_030807 Cc1cc(=O)oc2cc(OCCO)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E10 compound treatment 0.377 0.0349 2.9 0.357 0.0152 1.34 2.999 0.939 1382803 CBMicro_030808 CCOc1ccc(cc1)C(=O)Nc2ccc3nn(nc3c2)c4ccc(OCC)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E11 compound treatment 0.348 0.0059 0.49 0.338 -0.00384 -0.34 0.106 0.1777 1440311 CBMicro_030809 CCOc1ccc2nc(NC(=O)C(c3ccccc3)c4ccccc4)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E12 compound treatment 0.348 0.0059 0.49 0.342 1.61E-4 0.01 0.3566 0.7274 1217894 CBMicro_030810 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E13 compound treatment 0.338 -0.0041 -0.34 0.331 -0.0108 -0.96 -0.9197 -0.9026 1940958 CBMicro_030811 CCSc1nnc(NC(=O)C(C)(C)C)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E14 compound treatment 0.336 -0.0061 -0.51 0.318 -0.0238 -2.11 -1.8518 -0.8524 1940959 CBMicro_030812 CCC(C)c1ccc(NC(=O)c2cc(cc(c2)[N+](=O)[O-])C(=O)OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E15 compound treatment 0.374 0.0319 2.65 0.37 0.0282 2.5 3.6376 0.9996 1940960 CBMicro_030813 O=C(CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccco6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E16 compound treatment 0.37 0.0279 2.32 0.357 0.0152 1.34 2.5881 0.9664 1940961 CBMicro_030814 CC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E17 compound treatment 0.307 -0.0351 -2.91 0.301 -0.0408 -3.62 -4.6195 -0.9942 1596720 CBMicro_030815 C(N1CCN(CC1)C2CCC(CC2)c3ccccc3)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E18 compound treatment 0.333 -0.0091 -0.76 0.329 -0.0128 -1.14 -1.3385 -0.9802 1781933 CBMicro_030816 CN1C(=C(C(NC1=O)c2ccc(cc2)[N+](=O)[O-])C(=O)OCCc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E19 compound treatment 0.339 -0.0031 -0.26 0.338 -0.00384 -0.34 -0.4223 -0.9905 1940962 CBMicro_030817 Oc1ccccc1C(=O)/C=C/c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E20 compound treatment 0.34 -0.0021 -0.17 0.338 -0.00384 -0.34 -0.3636 -0.9516 1940963 CBMicro_030818 COC(=O)c1cccc(c1)N2C(=O)c3cccc([N+](=O)[O-])c3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E21 compound treatment 0.344 0.0019 0.16 0.345 0.00316 0.28 0.3098 0.9633 1539293 CBMicro_030819 C(N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)c4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E22 compound treatment 0.334 -0.0081 -0.67 0.334 -0.00784 -0.69 -0.9665 -0.9999 1245824 CBMicro_030820 Clc1c(sc2ccccc12)C(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E23 positive control 0.084 -0.258 -21.43 0.083 -0.259 -22.94 -31.3713 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 E24 positive control 0.091 -0.251 -20.85 0.09 -0.252 -22.32 -30.5217 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F01 mock treatment 0.337 -0.0051 -0.42 0.336 -0.00584 -0.52 -0.6651 -0.995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F02 mock treatment 0.343 9.03E-4 0.07 0.34 -0.00184 -0.16 -0.0622 -0.3468 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F03 compound treatment 0.334 -0.0081 -0.67 0.326 -0.0158 -1.4 -1.4678 -0.9432 1150278 CBMicro_030821 CCOc1ccccc1C(=O)Nc2cc(C)ccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F04 compound treatment 0.404 0.0619 5.14 0.404 0.0622 5.51 7.5293 0.9994 1940964 CBMicro_030822 Cc1ccc(NC(=O)/C=C/C(=O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F05 compound treatment 0.339 -0.0031 -0.26 0.335 -0.00684 -0.61 -0.6103 -0.9271 1379185 CBMicro_030823 CCc1ccccc1NC(=O)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F06 compound treatment 0.339 -0.0031 -0.26 0.332 -0.00984 -0.87 -0.7983 -0.8782 1940965 CBMicro_030824 Clc1ccccc1C(=O)Nn2cnnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F07 compound treatment 0.342 -9.68E-5 -0.01 0.336 -0.00584 -0.52 -0.3716 -0.718 1480247 CBMicro_030825 OC(COc1ccc(Cl)cc1)CS(=O)(=O)Cc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F08 compound treatment 0.367 0.0249 2.07 0.366 0.0242 2.14 2.976 0.9998 1940966 CBMicro_030826 COc1ccc(NC(=O)c2c(NC(=O)c3ccc(cc3)[N+](=O)[O-])sc4CCCCc24)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F09 compound treatment 0.404 0.0619 5.14 0.379 0.0372 3.29 5.9626 0.9769 1077241 CBMicro_030827 O=C(NC(=S)Nc1nc(cs1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F10 compound treatment 0.332 -0.0101 -0.84 0.32 -0.0218 -1.94 -1.9612 -0.9299 1625584 CBMicro_030828 CCOC(=O)c1ccccc1NC(=O)C(C)Oc2ccc(Cl)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F11 compound treatment 0.387 0.0449 3.73 0.374 0.0322 2.85 4.6514 0.9912 1940967 CBMicro_030829 Oc1cccc(NC(=O)/C(=C\c2cccnc2)/NC(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F12 compound treatment 0.384 0.0419 3.48 0.365 0.0232 2.05 3.9113 0.9683 1940968 CBMicro_030830 Cc1ccc(cc1)C(=O)Nc2cccc(NC(=O)c3cccc(Cl)c3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F13 compound treatment 0.325 -0.0171 -1.42 0.306 -0.0358 -3.18 -3.2495 -0.9341 1940969 CBMicro_030831 Clc1ccc(NC(=O)c2ccc(Br)o2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F14 compound treatment 0.331 -0.0111 -0.92 0.329 -0.0128 -1.14 -1.456 -0.9945 1940970 CBMicro_030832 COc1ccc(/C=N/n2cn[nH]c2=S)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F15 compound treatment 0.335 -0.0071 -0.59 0.334 -0.00784 -0.69 -0.9078 -0.9966 1940971 CBMicro_030833 Clc1ccc2c(=O)oc(nc2c1)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F16 compound treatment 0.323 -0.0191 -1.59 0.321 -0.0208 -1.85 -2.4269 -0.9971 1940972 CBMicro_030834 [O-][N+](=O)c1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F17 compound treatment 0.334 -0.0081 -0.67 0.332 -0.00984 -0.87 -1.0919 -0.9917 1940973 CBMicro_030835 Cc1cc(C)n(n1)c2ccc(nn2)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F18 compound treatment 0.337 -0.0051 -0.42 0.337 -0.00484 -0.43 -0.6024 -1.0 1940974 CBMicro_030836 CCOc1ccc(/C=C(\NC(=O)C)/C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F19 compound treatment 0.336 -0.0061 -0.51 0.332 -0.00984 -0.87 -0.9744 -0.9665 1940975 CBMicro_030837 CC(C)c1ccc(NC(=O)C2CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F20 compound treatment 0.335 -0.0071 -0.59 0.332 -0.00984 -0.87 -1.0331 -0.9818 1180783 CBMicro_030838 NC(=O)c1ccccc1NC(=O)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F21 compound treatment 0.333 -0.0091 -0.76 0.334 -0.00784 -0.69 -1.0252 -0.9991 1431149 CBMicro_030839 COCC(C)(C)NS(=O)(=O)c1ccccc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F22 compound treatment 0.336 -0.0061 -0.51 0.337 -0.00484 -0.43 -0.6611 -0.9966 1940976 CBMicro_030840 COc1cc(/C=N\n2c(C)nnc2C)ccc1OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F23 positive control 0.087 -0.255 -21.18 0.085 -0.257 -22.76 -31.0698 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 F24 positive control 0.092 -0.25 -20.76 0.089 -0.253 -22.41 -30.5257 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G01 mock treatment 0.337 -0.0051 -0.42 0.334 -0.00784 -0.69 -0.7904 -0.9717 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G02 mock treatment 0.34 -0.0021 -0.17 0.337 -0.00484 -0.43 -0.4263 -0.9211 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G03 compound treatment 0.33 -0.0121 -1.0 0.325 -0.0168 -1.49 -1.7653 -0.9814 1940977 CBMicro_030841 O=C/1NC(=S)N\C1=C\c2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G04 compound treatment 0.364 0.0219 1.82 0.36 0.0182 1.61 2.4239 0.9981 1940978 CBMicro_030842 COc1ccc(/C=C/2\SC(=O)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G05 compound treatment 0.333 -0.0091 -0.76 0.327 -0.0148 -1.32 -1.4639 -0.9653 1033786 CBMicro_030843 Fc1cccc(c1)C(=O)Nc2ccccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G06 compound treatment 0.337 -0.0051 -0.42 0.337 -0.00484 -0.43 -0.6024 -1.0 1300822 CBMicro_030844 O=C(COc1ccccc1)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G07 compound treatment 0.344 0.0019 0.16 0.341 -8.39E-4 -0.07 0.0592 0.3388 1940979 CBMicro_030845 COc1ccc(Cl)cc1C(=O)Nc2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G08 compound treatment 0.356 0.0139 1.15 0.366 0.0242 2.14 2.3302 0.958 1305707 CBMicro_030846 Cc1cc(Cl)ccc1NC(=O)c2ccc(CN(c3ccccc3)S(=O)(=O)C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G09 compound treatment 0.344 0.0019 0.16 0.341 -8.39E-4 -0.07 0.0592 0.3388 1721999 CBMicro_030847 COc1ccccc1N2CCN(CC(O)COc3ccc(cc3)C4(CC5CC6CC(C5)C4)C6)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G10 compound treatment 0.331 -0.0111 -0.92 0.324 -0.0178 -1.58 -1.7693 -0.967 1940980 CBMicro_030848 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G11 compound treatment 0.347 0.0049 0.41 0.341 -8.39E-4 -0.07 0.2353 0.5686 1784114 CBMicro_030849 COc1ccc(/C=C/2\CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C2O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G12 compound treatment 0.351 0.0089 0.74 0.346 0.00416 0.37 0.7834 0.9484 1940981 CBMicro_030850 CSCCOC(=O)COc1ccc(/C=N/NC(=O)c2ccc(CN3CCOCC3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G13 compound treatment 0.338 -0.0041 -0.34 0.332 -0.00984 -0.87 -0.857 -0.9157 1940982 CBMicro_030851 CCC(CC)C(=O)Nc1ccccc1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G14 compound treatment 0.316 -0.0261 -2.17 0.316 -0.0258 -2.29 -3.1512 -0.9996 1940983 CBMicro_030852 COc1cc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1OCc4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G15 compound treatment 0.346 0.0039 0.32 0.34 -0.00184 -0.16 0.1139 0.3141 1940984 CBMicro_030853 Cc1cccc(NC(=O)c2cnccn2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G16 compound treatment 0.376 0.0339 2.81 0.386 0.0442 3.91 4.7576 0.9869 1551733 CBMicro_030854 COc1cc2ccccc2cc1C(=O)Nc3cccc(c3)c4nc5ncccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G17 compound treatment 0.347 0.0049 0.41 0.346 0.00416 0.37 0.5486 0.9988 1276483 CBMicro_030855 COc1ccc(CN2CCN(CC2)C(=O)c3ccccc3F)cc1OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G18 compound treatment 0.357 0.0149 1.24 0.356 0.0142 1.26 1.7623 1.0 1940985 CBMicro_030856 O=c1[nH]c(SC/C=C/c2ccccc2)nc3sc4CCCCc4c13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G19 compound treatment 0.333 -0.0091 -0.76 0.332 -0.00984 -0.87 -1.1506 -0.9974 1543445 CBMicro_030857 O=C1N(C(=O)c2cc(ccc12)S(=O)(=O)c3ccc4C(=O)N(C(=O)c4c3)c5nccs5)c6nccs6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G20 compound treatment 0.357 0.0149 1.24 0.354 0.0122 1.08 1.637 0.9976 1511499 CBMicro_030858 CCOc1ccc(cc1OC)C2C(=C(C)NC(=C2C(=O)OC)C)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G21 compound treatment 0.334 -0.0081 -0.67 0.336 -0.00584 -0.52 -0.8412 -0.9916 1624608 CBMicro_030859 COc1ccc(CN2CCN(Cc3ccncc3)CC2)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G22 compound treatment 0.326 -0.0161 -1.34 0.327 -0.0148 -1.32 -1.8748 -1.0 1652862 CBMicro_030860 COc1ccc(NC(=O)C2CC2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G23 positive control 0.088 -0.254 -21.09 0.086 -0.256 -22.67 -30.9485 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 G24 positive control 0.093 -0.249 -20.68 0.092 -0.25 -22.14 -30.279 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H01 mock treatment 0.339 -0.0031 -0.26 0.335 -0.00684 -0.61 -0.6103 -0.9271 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H02 mock treatment 0.342 -9.68E-5 -0.01 0.34 -0.00184 -0.16 -0.1209 -0.7411 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H03 compound treatment 0.34 -0.0021 -0.17 0.339 -0.00284 -0.25 -0.301 -0.9838 1940986 CBMicro_030861 Clc1ccc(I)cc1C(=O)Nc2cccc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H04 compound treatment 0.327 -0.0151 -1.25 0.328 -0.0138 -1.23 -1.7534 -0.9999 1940987 CBMicro_030862 O=C(CCc1ccccc1)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H05 compound treatment 0.332 -0.0101 -0.84 0.331 -0.0108 -0.96 -1.2719 -0.9977 1940988 CBMicro_030863 [O-][N+](=O)c1ccc(NC(=O)c2cccnc2)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H06 compound treatment 0.34 -0.0021 -0.17 0.341 -8.39E-4 -0.07 -0.1756 -0.928 1940989 CBMicro_030864 [O-][N+](=O)c1cccc(c1)N(Cc2ccccc2)C(=O)CN3C(=O)c4ccccc4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H07 compound treatment 0.339 -0.0031 -0.26 0.332 -0.00984 -0.87 -0.7983 -0.8782 1258150 CBMicro_030865 CC1(C)OC2(NC1=O)C3CC4CC(C3)CC2C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H08 compound treatment 0.502 0.16 13.27 0.502 0.16 14.19 19.4234 0.9994 1547261 CBMicro_030866 CCOc1ccccc1NS(=O)(=O)c2ccc(OC)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H09 compound treatment 0.34 -0.0021 -0.17 0.338 -0.00384 -0.34 -0.3636 -0.9516 1940990 CBMicro_030867 CCc1nnc(NC(=S)NC(=O)c2ccccc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H10 compound treatment 0.362 0.0199 1.65 0.365 0.0232 2.05 2.6198 0.9942 1940991 CBMicro_030868 Brc1cccc(N/C=C/2\Sc3ccccc3C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H11 compound treatment 0.343 9.03E-4 0.07 0.343 0.00116 0.1 0.1258 0.9879 1940992 CBMicro_030869 CC(=C(NC(=O)c1ccccc1)C(=O)Nc2cccc(Br)c2)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H12 compound treatment 0.33 -0.0121 -1.0 0.317 -0.0248 -2.2 -2.2666 -0.9368 1940993 CBMicro_030870 COc1ccc(OCC(=O)N/N=C/c2ccc(OC)c(Br)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H13 compound treatment 0.335 -0.0071 -0.59 0.335 -0.00684 -0.61 -0.8452 -0.9999 1940994 CBMicro_030871 Clc1ccc(cc1Cl)C(=O)Nc2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H14 compound treatment 0.375 0.0329 2.73 0.379 0.0372 3.29 4.2602 0.9957 1022722 CBMicro_030872 O=S(=O)(NC1c2ccccc2Oc3ccccc13)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H15 compound treatment 0.343 9.03E-4 0.07 0.346 0.00416 0.37 0.3138 0.8338 1940995 CBMicro_030873 COc1cccc(/C=N/NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H16 compound treatment 0.333 -0.0091 -0.76 0.333 -0.00884 -0.78 -1.0879 -0.9998 1940996 CBMicro_030874 OCCSc1nncn1/N=C/c2c[nH]c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H17 compound treatment 0.324 -0.0181 -1.5 0.326 -0.0158 -1.4 -2.0549 -0.9994 1940997 CBMicro_030875 CCOc1ccccc1NC(=O)C2(CC2(Cl)Cl)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H18 compound treatment 0.341 -0.0011 -0.09 0.34 -0.00184 -0.16 -0.1796 -0.9622 1940998 CBMicro_030876 Cc1onc(c1C(=O)Nc2ccc(C)c(Cl)c2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H19 compound treatment 0.34 -0.0021 -0.17 0.36 0.0182 1.61 1.015 0.627 1698936 CBMicro_030877 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)Cc5ccco5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H20 compound treatment 0.339 -0.0031 -0.26 0.342 1.61E-4 0.01 -0.1717 -0.6668 1307727 CBMicro_030878 CC(C)OC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H21 compound treatment 0.331 -0.0111 -0.92 0.33 -0.0118 -1.05 -1.3933 -0.9979 1175708 CBMicro_030879 OC(=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H22 compound treatment 0.327 -0.0151 -1.25 0.328 -0.0138 -1.23 -1.7534 -0.9999 1940999 CBMicro_030880 Fc1ccc(/C=N/N2CCN(Cc3ccccc3)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H23 positive control 0.088 -0.254 -21.09 0.086 -0.256 -22.67 -30.9485 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 H24 positive control 0.094 -0.248 -20.6 0.093 -0.249 -22.05 -30.1576 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I01 mock treatment 0.346 0.0039 0.32 0.343 0.00116 0.1 0.3019 0.888 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I02 mock treatment 0.346 0.0039 0.32 0.345 0.00316 0.28 0.4272 0.9974 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I03 compound treatment 0.336 -0.0061 -0.51 0.332 -0.00984 -0.87 -0.9744 -0.9665 1941000 CBMicro_030881 Fc1ccc(cc1)C(=O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I04 compound treatment 0.334 -0.0081 -0.67 0.334 -0.00784 -0.69 -0.9665 -0.9999 1479000 CBMicro_030882 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Cl)cc3Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I05 compound treatment 0.335 -0.0071 -0.59 0.331 -0.0108 -0.96 -1.0958 -0.9725 1941001 CBMicro_030883 Fc1cccc(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I06 compound treatment 0.49 0.148 12.28 0.484 0.142 12.6 17.591 0.9999 1126490 CBMicro_030884 CN1CCc2c(C1)sc3NC(NC(=O)c23)c4ccc(Cl)s4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I07 compound treatment 0.333 -0.0091 -0.76 0.34 -0.00184 -0.16 -0.6492 -0.8403 1260558 CBMicro_030885 Cc1ccc(C)c(NC(=O)C2CC3CCC2C3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I08 compound treatment 0.354 0.0119 0.99 0.349 0.00716 0.63 1.1475 0.9771 1402039 CBMicro_030886 O=C(CN1C(=O)c2ccccc2C1=O)Nc3cccc(C#C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I09 compound treatment 0.366 0.0239 1.98 0.345 0.00316 0.28 1.6013 0.799 1707463 CBMicro_030887 OC(COc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)CN5CCN(CC5)c6ccccn6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I10 compound treatment 0.501 0.159 13.19 0.484 0.142 12.6 18.2367 0.9997 1941002 CBMicro_030888 COc1cccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I11 compound treatment 0.351 0.0089 0.74 0.357 0.0152 1.34 1.4727 0.9604 1941003 CBMicro_030889 [O-][N+](=O)c1ccc(/C=C/C(=O)c2ccc(Br)cc2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I12 compound treatment 0.383 0.0409 3.4 0.383 0.0412 3.65 4.9805 0.9994 1941004 CBMicro_030890 Clc1ccc(Cl)c(c1)c2ccc(C=C(C#N)C#N)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I13 compound treatment 0.344 0.0019 0.16 0.336 -0.00584 -0.52 -0.2542 -0.4698 1514060 CBMicro_030891 CCCOC(=O)c1ccc(NC(=O)OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I14 compound treatment 0.333 -0.0091 -0.76 0.366 0.0242 2.14 0.9801 0.4317 1664770 CBMicro_030892 CN(c1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I15 compound treatment 0.329 -0.0131 -1.09 0.324 -0.0178 -1.58 -1.8867 -0.9833 1941005 CBMicro_030893 CCC(C(=O)Nc1ccccc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I16 compound treatment 0.349 0.0069 0.57 0.332 -0.00984 -0.87 -0.2113 -0.2025 1131821 CBMicro_030894 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(cc3)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I17 compound treatment 0.377 0.0349 2.9 0.374 0.0322 2.85 4.0643 1.0 1941006 CBMicro_030895 CCOC(=O)NC(NC(=S)Nc1ccc(NC(=O)C)cc1)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I18 compound treatment 0.352 0.0099 0.82 0.358 0.0162 1.43 1.5941 0.9653 1941007 CBMicro_030896 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccccc4[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I19 compound treatment 0.333 -0.0091 -0.76 0.339 -0.00284 -0.25 -0.7119 -0.8943 1381183 CBMicro_030897 Cc1ccc(cc1)S(=O)(=O)N(C2CS(=O)(=O)C=C2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I20 compound treatment 0.359 0.0169 1.4 0.369 0.0272 2.41 2.6943 0.967 1941008 CBMicro_030898 COCCOC(=O)c1ccc(NC(=O)c2ccccc2CCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I21 compound treatment 0.322 -0.0201 -1.67 0.32 -0.0218 -1.94 -2.5483 -0.9973 1941009 CBMicro_030899 CCC1(C)CC(CCNCc2ccc(cc2)N(C)C)(CCO1)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I22 compound treatment 0.24 -0.102 -8.48 0.266 -0.0758 -6.72 -10.7459 -0.9934 1941010 CBMicro_030900 Fc1ccc(cc1)C(=O)/C=C/c2ccc(o2)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I23 positive control 0.09 -0.252 -20.93 0.088 -0.254 -22.5 -30.7057 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 I24 positive control 0.094 -0.248 -20.6 0.094 -0.248 -21.96 -30.0949 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J01 mock treatment 0.321 -0.0211 -1.75 0.316 -0.0258 -2.29 -2.8576 -0.9912 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J02 mock treatment 0.348 0.0059 0.49 0.35 0.00816 0.72 0.858 0.982 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J03 compound treatment 0.332 -0.0101 -0.84 0.329 -0.0128 -1.14 -1.3973 -0.9887 1369271 CBMicro_030901 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3CC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J04 compound treatment 0.335 -0.0071 -0.59 0.336 -0.00584 -0.52 -0.7825 -0.9979 1941011 CBMicro_030902 CC(NC(=O)c1cccc(F)c1)C2CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J05 compound treatment 0.34 -0.0021 -0.17 0.332 -0.00984 -0.87 -0.7396 -0.8319 1661998 CBMicro_030903 Cc1cc(NC(=O)c2ccncc2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J06 compound treatment 0.341 -0.0011 -0.09 0.34 -0.00184 -0.16 -0.1796 -0.9622 1022775 CBMicro_030904 O=C(NCc1ccccc1)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J07 compound treatment 0.347 0.0049 0.41 0.335 -0.00684 -0.61 -0.1407 -0.1927 1301061 CBMicro_030905 Cc1ccc(cc1)C(=O)Nc2nnn[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J08 compound treatment 0.339 -0.0031 -0.26 0.329 -0.0128 -1.14 -0.9863 -0.8456 1230763 CBMicro_030906 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J09 compound treatment 0.355 0.0129 1.07 0.35 0.00816 0.72 1.2689 0.9817 1941012 CBMicro_030907 ClC1=CCC2C(C1)C(=O)N(CN(CN3C(=O)C4CC=C(Cl)CC4C3=O)Cc5ccco5)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J10 compound treatment 0.345 0.0029 0.24 0.344 0.00216 0.19 0.3059 0.9935 1941013 CBMicro_030908 OCCCNS(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)NCCCO)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J11 compound treatment 0.364 0.0219 1.82 0.356 0.0142 1.26 2.1732 0.9836 1614780 CBMicro_030909 CC(=C(NC(=O)c1ccccc1)C(=O)Nc2cccc(C)c2)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J12 compound treatment 0.347 0.0049 0.41 0.342 1.61E-4 0.01 0.2979 0.7315 1941014 CBMicro_030910 Cc1n[nH]c(=S)n(/N=C/c2ccco2)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J13 compound treatment 0.336 -0.0061 -0.51 0.335 -0.00684 -0.61 -0.7864 -0.996 1941015 CBMicro_030911 Fc1c(F)c(F)c(NC(=O)c2ccco2)c(F)c1F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J14 compound treatment 0.337 -0.0051 -0.42 0.34 -0.00184 -0.16 -0.4144 -0.914 1580481 CBMicro_030912 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4ccc(O)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J15 compound treatment 0.41 0.0679 5.64 0.409 0.0672 5.95 8.1948 0.9996 1941016 CBMicro_030913 CCCCCCCN1C(=O)/C(=C/2\SC(=S)NC2=O)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J16 compound treatment 0.322 -0.0201 -1.67 0.34 -0.00184 -0.16 -1.295 -0.7725 1941017 CBMicro_030914 Cc1cc(Cl)ccc1OCCCC(=O)NO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J17 compound treatment 0.342 -9.68E-5 -0.01 0.345 0.00316 0.28 0.1924 0.6865 1167883 CBMicro_030915 COc1ccc2C(Nc3ccc(I)cc3)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J18 compound treatment 0.404 0.0619 5.14 0.383 0.0412 3.65 6.2133 0.9859 1941018 CBMicro_030916 O=C(Nc1nc(cs1)c2cccc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J19 compound treatment 0.349 0.0069 0.57 0.314 -0.0278 -2.47 -1.3393 -0.5288 1359495 CBMicro_030917 COC(=O)c1cccc(NC(=O)COc2ccccc2C(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J20 compound treatment 0.386 0.0439 3.64 0.384 0.0422 3.74 5.2193 0.9999 1941019 CBMicro_030918 CCOc1ccc(NC(=O)c2c(C)onc2c3ccccc3Cl)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J21 compound treatment 0.342 -9.68E-5 -0.01 0.337 -0.00484 -0.43 -0.3089 -0.7202 1941020 CBMicro_030919 COc1ccc(/C=N/NC(=O)c2ccc(Br)o2)c(C(=O)O)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J22 compound treatment 0.341 -0.0011 -0.09 0.341 -8.39E-4 -0.07 -0.1169 -0.9949 1941021 CBMicro_030920 CCOc1ccccc1/C=N\n2c(C)nnc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J23 positive control 0.088 -0.254 -21.09 0.089 -0.253 -22.41 -30.7605 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 J24 positive control 0.095 -0.247 -20.51 0.093 -0.249 -22.05 -30.0989 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K01 mock treatment 0.346 0.0039 0.32 0.343 0.00116 0.1 0.3019 0.888 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K02 mock treatment 0.346 0.0039 0.32 0.344 0.00216 0.19 0.3646 0.9685 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K03 compound treatment 0.349 0.0069 0.57 0.344 0.00216 0.19 0.5407 0.8948 1941022 CBMicro_030921 Cc1ccc2nc(NCc3ccccc3)nc(c4ccccc4)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K04 compound treatment 0.343 9.03E-4 0.07 0.343 0.00116 0.1 0.1258 0.9879 1941023 CBMicro_030922 Nc1nonc1/C(=N/O)/N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K05 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1941024 CBMicro_030923 Fc1cccc(c1)C(=O)Nc2c(F)c(F)c(F)c(F)c2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K06 compound treatment 0.343 9.03E-4 0.07 0.332 -0.00984 -0.87 -0.5635 -0.6439 1672015 CBMicro_030924 CC(=O)Nc1ccccc1NC(=O)Cc2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K07 compound treatment 0.34 -0.0021 -0.17 0.329 -0.0128 -1.14 -0.9276 -0.8059 1504650 CBMicro_030925 CCOC(=O)N1CCN(CC1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K08 compound treatment 0.34 -0.0021 -0.17 0.341 -8.39E-4 -0.07 -0.1756 -0.928 1941025 CBMicro_030926 COc1ccc(/C=C\2/SC(=O)N(CNc3cc(F)ccc3C)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K09 compound treatment 0.347 0.0049 0.41 0.344 0.00216 0.19 0.4233 0.9409 1941026 CBMicro_030927 Cc1ccc(cc1NC(=O)CC2Sc3ccccc3NC2=O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K10 compound treatment 0.337 -0.0051 -0.42 0.334 -0.00784 -0.69 -0.7904 -0.9717 1941027 CBMicro_030928 O=C(CN1C(=O)c2cccc3cccc(C1=O)c23)OCc4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K11 compound treatment 0.369 0.0269 2.23 0.372 0.0302 2.67 3.4694 0.996 1941028 CBMicro_030929 Cc1ccc(/C=C(/NC(=O)c2ccccc2I)\C(=O)Nc3ccc(C)cc3)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K12 compound treatment 0.341 -0.0011 -0.09 0.342 1.61E-4 0.01 -0.0543 -0.5889 1941029 CBMicro_030930 COCCOC(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K13 compound treatment 0.34 -0.0021 -0.17 0.34 -0.00184 -0.16 -0.2383 -0.9995 1736302 CBMicro_030931 COc1ccc2[nH]cc(CCC(=O)O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K14 compound treatment 0.339 -0.0031 -0.26 0.332 -0.00984 -0.87 -0.7983 -0.8782 1614190 CBMicro_030932 COc1ccc(NC(=O)c2ccc(cc2C(=O)O)C(=O)O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K15 compound treatment 0.346 0.0039 0.32 0.347 0.00516 0.46 0.5526 0.9857 1941030 CBMicro_030933 CCc1ccc(NC(=O)c2cnccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K16 compound treatment 0.331 -0.0111 -0.92 0.335 -0.00684 -0.61 -1.08 -0.9794 1121162 CBMicro_030934 Cc1cc(NC(=O)c2ccco2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K17 compound treatment 0.384 0.0419 3.48 0.397 0.0552 4.89 5.9165 0.9861 1941031 CBMicro_030935 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2cccc(c2)[N+](=O)[O-])C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K18 compound treatment 0.346 0.0039 0.32 0.344 0.00216 0.19 0.3646 0.9685 1664897 CBMicro_030936 Brc1ccc(I)c(c1)C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K19 compound treatment 0.382 0.0399 3.31 0.375 0.0332 2.94 4.4205 0.9982 1941032 CBMicro_030937 CCOc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N(CC)CC)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K20 compound treatment 0.342 -9.68E-5 -0.01 0.343 0.00116 0.1 0.0671 0.6499 1941033 CBMicro_030938 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccc(C)c(c4)[N+](=O)[O-])c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K21 compound treatment 0.078 -0.264 -21.93 0.077 -0.265 -23.47 -32.0995 -0.9994 1626833 CBMicro_030939 COc1cc(ccc1O)c2csc(N)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K22 compound treatment 0.357 0.0149 1.24 0.359 0.0172 1.52 1.9503 0.9948 1603032 CBMicro_030940 CCOc1ccc(cc1)C(=O)Nc2ccc(cc2)C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K23 positive control 0.087 -0.255 -21.18 0.087 -0.255 -22.58 -30.9445 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 K24 positive control 0.096 -0.246 -20.43 0.096 -0.246 -21.79 -29.8522 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L01 mock treatment 0.341 -0.0011 -0.09 0.342 1.61E-4 0.01 -0.0543 -0.5889 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L02 mock treatment 0.343 9.03E-4 0.07 0.345 0.00316 0.28 0.2511 0.8659 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L03 compound treatment 0.335 -0.0071 -0.59 0.329 -0.0128 -1.14 -1.2211 -0.9531 1941034 CBMicro_030941 CC(=O)c1ccc(cc1)N2C(=O)c3ccc(Oc4ccc5C(=O)N(C(=O)c5c4)c6ccc(cc6)C(=O)C)cc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L04 compound treatment 0.334 -0.0081 -0.67 0.331 -0.0108 -0.96 -1.1545 -0.9848 1941035 CBMicro_030942 CC(NC(=O)c1ccc(F)cc1)C2CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L05 compound treatment 0.336 -0.0061 -0.51 0.336 -0.00584 -0.52 -0.7238 -0.9999 1560026 CBMicro_030943 Clc1ccc(NC(=O)c2ccncc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L06 compound treatment 0.336 -0.0061 -0.51 0.335 -0.00684 -0.61 -0.7864 -0.996 1941036 CBMicro_030944 FC(F)(F)C(=O)Nc1ccccc1C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L07 compound treatment 0.348 0.0059 0.49 0.341 -8.39E-4 -0.07 0.294 0.5931 1941037 CBMicro_030945 Cc1cc(=O)oc2cc(OC(=O)CCCOc3ccc(Cl)cc3Cl)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L08 compound treatment 0.323 -0.0191 -1.59 0.333 -0.00884 -0.78 -1.6749 -0.9472 1206774 CBMicro_030946 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L09 compound treatment 0.333 -0.0091 -0.76 0.335 -0.00684 -0.61 -0.9626 -0.9941 1362820 CBMicro_030947 CC(=O)Nc1ccc(cc1)c2csc(N)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L10 compound treatment 0.338 -0.0041 -0.34 0.338 -0.00384 -0.34 -0.481 -1.0 1941038 CBMicro_030948 CN(CCCC(=O)O)S(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)N(C)CCCC(=O)O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L11 compound treatment 0.335 -0.0071 -0.59 0.336 -0.00584 -0.52 -0.7825 -0.9979 1941039 CBMicro_030949 OC(=O)CNC(=O)/C(=C\c1cccnc1)/NC(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L12 compound treatment 0.333 -0.0091 -0.76 0.333 -0.00884 -0.78 -1.0879 -0.9998 1247613 CBMicro_030950 Cc1cc(C)cc(NC(=O)c2ccncc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L13 compound treatment 0.331 -0.0111 -0.92 0.334 -0.00784 -0.69 -1.1426 -0.9903 1941040 CBMicro_030951 Fc1c(F)c(F)c(NC(=O)c2cccs2)c(F)c1F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L14 compound treatment 0.34 -0.0021 -0.17 0.345 0.00316 0.28 0.075 0.2274 1941041 CBMicro_030952 COc1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L15 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1371101 CBMicro_030953 Cc1onc(c1C(=O)Nc2ccc(C)cn2)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L16 compound treatment 0.337 -0.0051 -0.42 0.342 1.61E-4 0.01 -0.2891 -0.6828 1941042 CBMicro_030954 COc1ccc(/C=N/n2cnnc2SC)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L17 compound treatment 0.373 0.0309 2.57 0.382 0.0402 3.56 4.3308 0.9871 1941043 CBMicro_030955 Cn1c(=O)c([N+](=O)[O-])c(N2CCN(CC2)C(c3ccccc3)c4ccccc4)c5ccccc15 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L18 compound treatment 0.334 -0.0081 -0.67 0.336 -0.00584 -0.52 -0.8412 -0.9916 1714197 CBMicro_030956 Cc1onc(c1C(=O)Nc2ccc3OCOc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L19 compound treatment 0.33 -0.0121 -1.0 0.323 -0.0188 -1.67 -1.8907 -0.9704 1941044 CBMicro_030957 CCOCCOC(=O)C(C)Sc1n[nH]c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L20 compound treatment 0.339 -0.0031 -0.26 0.341 -8.39E-4 -0.07 -0.2343 -0.8757 1378627 CBMicro_030958 Cc1occc1C(=O)NCc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L21 compound treatment 0.326 -0.0161 -1.34 0.326 -0.0158 -1.4 -1.9375 -0.9997 1725157 CBMicro_030959 COC(=O)c1c(C)c(C)sc1NC(=O)Cc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L22 compound treatment 0.36 0.0179 1.49 0.353 0.0112 0.99 1.7504 0.9804 1941045 CBMicro_030960 CC/1=NN(C(=O)\C1=C\c2cccn2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L23 positive control 0.089 -0.253 -21.01 0.088 -0.254 -22.5 -30.7644 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 L24 positive control 0.095 -0.247 -20.51 0.095 -0.247 -21.88 -29.9736 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M01 mock treatment 0.34 -0.0021 -0.17 0.34 -0.00184 -0.16 -0.2383 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M02 mock treatment 0.342 -9.68E-5 -0.01 0.339 -0.00284 -0.25 -0.1836 -0.7293 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M03 compound treatment 0.166 -0.176 -14.62 0.183 -0.159 -14.08 -20.2911 -0.9998 1941046 CBMicro_030961 Brc1cccc(c1)c2ccc(/C=C/C(=O)c3cccs3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M04 compound treatment 0.437 0.0949 7.88 0.433 0.0912 8.08 11.2838 0.9999 1941047 CBMicro_030962 CN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3cccnc3)C2=O)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M05 compound treatment 0.358 0.0159 1.32 0.369 0.0272 2.41 2.6356 0.96 1725934 CBMicro_030963 COC(=O)c1ccccc1NC(=O)c2cc3ccccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M06 compound treatment 0.34 -0.0021 -0.17 0.338 -0.00384 -0.34 -0.3636 -0.9516 1941048 CBMicro_030964 COc1ccc(/C=C/C(=O)Nc2ccc(F)cc2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M07 compound treatment 0.324 -0.0181 -1.5 0.325 -0.0168 -1.49 -2.1175 -1.0 1165983 CBMicro_030965 CCC(C(=O)Nc1ccc(C)cc1C)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M08 compound treatment 0.33 -0.0121 -1.0 0.331 -0.0108 -0.96 -1.3893 -0.9998 1290421 CBMicro_030966 Cc1nn(C(=O)CCN2C(=O)c3ccccc3C2=O)c(C)c1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M09 compound treatment 0.325 -0.0171 -1.42 0.322 -0.0198 -1.76 -2.2468 -0.9944 1941049 CBMicro_030967 Cc1ccc(NC(=O)/C(=C\c2ccco2)/NC(=O)c3ccccc3I)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M10 compound treatment 0.336 -0.0061 -0.51 0.33 -0.0118 -1.05 -1.0998 -0.9441 1941050 CBMicro_030968 Oc1ccc(cc1)c2cc(nc(n2)c3ccccc3)c4ccc(O)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M11 compound treatment 0.377 0.0349 2.9 0.361 0.0192 1.7 3.2497 0.9676 1941051 CBMicro_030969 Cc1ccc(s1)C(=O)/C=C/c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M12 compound treatment 0.354 0.0119 0.99 0.364 0.0222 1.96 2.0875 0.9495 1941052 CBMicro_030970 Oc1ccc(cc1)N2C(=O)S/C(=C/3\C(=O)Nc4ccc(Br)cc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M13 compound treatment 0.341 -0.0011 -0.09 0.342 1.61E-4 0.01 -0.0543 -0.5889 1941053 CBMicro_030971 OC(=O)/C=C/C(=O)Nc1ccc2OCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M14 compound treatment 0.569 0.227 18.84 0.563 0.221 19.6 27.1791 0.9998 1941054 CBMicro_030972 OC(=O)c1ccccc1/C=C\2/SC(=S)N(C2=O)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M15 compound treatment 0.343 9.03E-4 0.07 0.34 -0.00184 -0.16 -0.0622 -0.3468 1118719 CBMicro_030973 Clc1ccc(Cl)c(Cc2cnc(s2)N3C(=O)c4ccccc4C3=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M16 compound treatment 0.328 -0.0141 -1.17 0.325 -0.0168 -1.49 -1.8827 -0.9928 1609452 CBMicro_030974 Cc1cc(C)c(NC(=O)c2cccs2)c(C)c1NC(=O)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M17 compound treatment 0.33 -0.0121 -1.0 0.331 -0.0108 -0.96 -1.3893 -0.9998 1941055 CBMicro_030975 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)cc(Cl)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M18 compound treatment 0.841 0.499 41.42 0.838 0.496 43.97 60.3793 0.9996 1941056 CBMicro_030976 OC(=O)CCCCCN1C(=O)/C(=C/c2ccc(O)c(O)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M19 compound treatment 0.329 -0.0131 -1.09 0.331 -0.0108 -0.96 -1.448 -0.9981 1510652 CBMicro_030977 Oc1ccc(NC(=O)CC2Nc3ccccc3NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M20 compound treatment 0.388 0.0459 3.81 0.392 0.0502 4.45 5.838 0.9971 1941057 CBMicro_030978 COc1cc(/C=C/2\SC(=S)N(Nc3ccccc3)C2=O)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M21 compound treatment 0.314 -0.0281 -2.33 0.317 -0.0248 -2.2 -3.2059 -0.9996 1941058 CBMicro_030979 CCC1(C)CC(CCNCc2ccc(cc2)N(C)C)(CCO1)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M22 compound treatment 0.378 0.0359 2.98 0.363 0.0212 1.88 3.4337 0.9751 1298168 CBMicro_030980 CCOc1ccc(cc1)C(=O)Nc2ccccc2C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M23 positive control 0.089 -0.253 -21.01 0.089 -0.253 -22.41 -30.7018 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 M24 positive control 0.096 -0.246 -20.43 0.096 -0.246 -21.79 -29.8522 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N01 mock treatment 0.343 9.03E-4 0.07 0.344 0.00216 0.19 0.1885 0.9162 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N02 mock treatment 0.349 0.0069 0.57 0.348 0.00616 0.55 0.7913 0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N03 compound treatment 0.339 -0.0031 -0.26 0.337 -0.00484 -0.43 -0.485 -0.9701 1582065 CBMicro_030981 Fc1ccc(cc1)C(=O)Nc2ccccc2NC(=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N04 compound treatment 0.344 0.0019 0.16 0.341 -8.39E-4 -0.07 0.0592 0.3388 1941059 CBMicro_030982 COc1ccc(cc1)N(C(C)C2CC2)C(=O)Nc3ccccc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N05 compound treatment 0.35 0.0079 0.66 0.349 0.00716 0.63 0.9127 0.9999 1165498 CBMicro_030983 Fc1ccccc1C(=O)Nc2nc3ccc(Cl)cc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N06 compound treatment 0.271 -0.0711 -5.9 0.269 -0.0728 -6.46 -8.7381 -0.999 1025992 CBMicro_030984 Nc1ccc(cc1)C(c2ccccc2)c3ccc(N)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N07 compound treatment 0.356 0.0139 1.15 0.354 0.0122 1.08 1.5783 0.9994 1941060 CBMicro_030985 OC(=O)c1cc(ccc1O)c2ccc(C=C3C(=O)c4ccccc4C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N08 compound treatment 0.379 0.0369 3.06 0.379 0.0372 3.29 4.4951 0.9993 1872610 CBMicro_030986 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc4OCOc4cc3[N+](=O)[O-])C(=O)OC5CCCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N09 compound treatment 0.337 -0.0051 -0.42 0.338 -0.00384 -0.34 -0.5398 -0.9941 1707162 CBMicro_030987 Brc1ccc(cc1)C(=O)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N10 compound treatment 0.555 0.213 17.68 0.56 0.218 19.33 26.1692 0.999 1941061 CBMicro_030988 [O-][N+](=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N11 compound treatment 0.326 -0.0161 -1.34 0.325 -0.0168 -1.49 -2.0001 -0.9985 1665639 CBMicro_030989 CCOc1ccc(c2ccccc12)S(=O)(=O)NCc3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N12 compound treatment 0.382 0.0399 3.31 0.374 0.0322 2.85 4.3578 0.9972 1941062 CBMicro_030990 Brc1ccc(/N=C/2\C(=O)Nc3ccccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N13 compound treatment 0.34 -0.0021 -0.17 0.342 1.61E-4 0.01 -0.113 -0.6469 1687142 CBMicro_030991 Fc1ccc(cc1)C(=O)Nc2c(Cl)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N14 compound treatment 0.349 0.0069 0.57 0.348 0.00616 0.55 0.7913 0.9997 1272988 CBMicro_030992 COc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccncc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N15 compound treatment 0.343 9.03E-4 0.07 0.337 -0.00484 -0.43 -0.2502 -0.5747 1941063 CBMicro_030993 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3nc4ccc(Br)cc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N16 compound treatment 0.339 -0.0031 -0.26 0.336 -0.00584 -0.52 -0.5477 -0.9479 1941064 CBMicro_030994 COc1ccc(CSc2nnc[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N17 compound treatment 0.33 -0.0121 -1.0 0.328 -0.0138 -1.23 -1.5773 -0.9951 1941065 CBMicro_030995 C=CCSc1nc2ccccc2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N18 compound treatment 0.337 -0.0051 -0.42 0.336 -0.00584 -0.52 -0.6651 -0.995 1252739 CBMicro_030996 Cc1ccccc1N2C(=O)C(O)C(O)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N19 compound treatment 0.361 0.0189 1.57 0.36 0.0182 1.61 2.2478 0.9999 1864171 CBMicro_030997 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N20 compound treatment 0.343 9.03E-4 0.07 0.334 -0.00784 -0.69 -0.4382 -0.6271 1319606 CBMicro_030998 Cn1c(NC(=O)c2ccco2)cc(=O)n(C)c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N21 compound treatment 0.349 0.0069 0.57 0.35 0.00816 0.72 0.9167 0.9934 1373228 CBMicro_030999 CC(Oc1ccc(Cl)cc1C)C(=O)NCC2CCCO2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N22 compound treatment 0.334 -0.0081 -0.67 0.333 -0.00884 -0.78 -1.0292 -0.9971 1035047 CBMicro_031000 Cc1cc(Cl)ccc1OCC(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N23 positive control 0.089 -0.253 -21.01 0.09 -0.252 -22.32 -30.6391 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 N24 positive control 0.094 -0.248 -20.6 0.094 -0.248 -21.96 -30.0949 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O01 mock treatment 0.345 0.0029 0.24 0.344 0.00216 0.19 0.3059 0.9935 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O02 mock treatment 0.352 0.0099 0.82 0.344 0.00216 0.19 0.7168 0.8491 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O03 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1941066 CBMicro_031001 Cc1cccc(NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O04 compound treatment 0.345 0.0029 0.24 0.343 0.00116 0.1 0.2432 0.928 1304559 CBMicro_031002 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc3C(=O)N(C(=O)c3c2)c4nc5ccccc5s4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O05 compound treatment 0.358 0.0159 1.32 0.362 0.0202 1.79 2.197 0.9889 1550455 CBMicro_031003 Cc1ccc(cc1)c2cc(OC(=O)c3ccccc3)cc4sc(=O)oc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O06 compound treatment 0.34 -0.0021 -0.17 0.335 -0.00684 -0.61 -0.5516 -0.8748 1330384 CBMicro_031004 CCN(CC)S(=O)(=O)c1ccc2OCCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O07 compound treatment 0.325 -0.0171 -1.42 0.325 -0.0168 -1.49 -2.0588 -0.9997 1941067 CBMicro_031005 FC(F)Oc1ccc(NC(=O)c2cccs2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O08 compound treatment 0.343 9.03E-4 0.07 0.343 0.00116 0.1 0.1258 0.9879 1226157 CBMicro_031006 COc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O09 compound treatment 0.361 0.0189 1.57 0.36 0.0182 1.61 2.2478 0.9999 1941068 CBMicro_031007 COc1cc(/C=C/C(=O)c2c(c3ccccc3)c4cc(Cl)ccc4[nH]c2=O)cc(Br)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O10 compound treatment 0.355 0.0129 1.07 0.353 0.0112 0.99 1.4569 0.9992 1941069 CBMicro_031008 CCCCOc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C)(C)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O11 compound treatment 0.375 0.0329 2.73 0.377 0.0352 3.12 4.1349 0.9978 1784502 CBMicro_031009 [O-][N+](=O)c1ccc(cc1)C2CC(=Nc3ccccc3N2)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O12 compound treatment 0.409 0.0669 5.55 0.451 0.109 9.67 10.768 0.9653 1941070 CBMicro_031010 NC(=O)/C(=C/c1ccc(o1)c2ccc(Br)cc2)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O13 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1941071 CBMicro_031011 CCOC(=O)c1c(NC(=O)c2cccc(c2)[N+](=O)[O-])sc3CC(CC)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O14 compound treatment 0.361 0.0189 1.57 0.36 0.0182 1.61 2.2478 0.9999 1941072 CBMicro_031012 CN/1C(=O)\C(=C\C(=O)O)\S\C1=N\NC(=O)OC(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O15 compound treatment 0.393 0.0509 4.23 0.37 0.0282 2.5 4.7529 0.9684 1941073 CBMicro_031013 [O-][N+](=O)c1ccccc1NC(=O)c2ccc3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O16 compound treatment 0.313 -0.0291 -2.42 0.313 -0.0288 -2.56 -3.5153 -0.9996 1941074 CBMicro_031014 CCOc1cc(/C=C/2\SC(=S)N(Nc3ccccc3)C2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O17 compound treatment 0.394 0.0519 4.31 0.396 0.0542 4.8 6.4409 0.9986 1653107 CBMicro_031015 Clc1ccccc1NC(=O)c2ccc3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O18 compound treatment 0.382 0.0399 3.31 0.387 0.0452 4.0 5.1725 0.9956 1676656 CBMicro_031016 CC(C)(C)c1ccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)N)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O19 compound treatment 0.335 -0.0071 -0.59 0.332 -0.00984 -0.87 -1.0331 -0.9818 1148217 CBMicro_031017 OC(CSc1nnc(Cc2ccccc2)n1CC=C)Cn3c4ccccc4c5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O20 compound treatment 0.375 0.0329 2.73 0.373 0.0312 2.76 3.8843 1.0 1642408 CBMicro_031018 Cc1cc(NC(=O)c2cccc(Br)c2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O21 compound treatment 0.325 -0.0171 -1.42 0.325 -0.0168 -1.49 -2.0588 -0.9997 1941075 CBMicro_031019 CCC1(C)CC(CCNCc2ccc(OC)cc2)(CCO1)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O22 compound treatment 0.339 -0.0031 -0.26 0.339 -0.00284 -0.25 -0.3597 -0.9999 1941076 CBMicro_031020 CCc1ccc(NC(=O)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O23 positive control 0.09 -0.252 -20.93 0.089 -0.253 -22.41 -30.6431 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 O24 positive control 0.095 -0.247 -20.51 0.095 -0.247 -21.88 -29.9736 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P01 mock treatment 0.341 -0.0011 -0.09 0.339 -0.00284 -0.25 -0.2423 -0.9055 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P02 mock treatment 0.343 9.03E-4 0.07 0.341 -8.39E-4 -0.07 5.0E-4 0.0044 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P03 compound treatment 0.336 -0.0061 -0.51 0.334 -0.00784 -0.69 -0.8491 -0.9879 1650671 CBMicro_031021 Oc1ccccc1C(=O)Nc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P04 compound treatment 0.33 -0.0121 -1.0 0.329 -0.0128 -1.14 -1.5147 -0.9981 1652425 CBMicro_031022 COc1ccccc1N(C(C)C2CC2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P05 compound treatment 0.34 -0.0021 -0.17 0.34 -0.00184 -0.16 -0.2383 -0.9995 1941077 CBMicro_031023 Brc1ccc(cc1)C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P06 compound treatment 0.341 -0.0011 -0.09 0.339 -0.00284 -0.25 -0.2423 -0.9055 1260957 CBMicro_031024 COc1cc(ccc1NC(=O)c2ccc(F)cc2)c3ccc(NC(=O)c4ccc(F)cc4)c(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P07 compound treatment 0.334 -0.0081 -0.67 0.334 -0.00784 -0.69 -0.9665 -0.9999 1465620 CBMicro_031025 NS(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)N)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P08 compound treatment 0.307 -0.0351 -2.91 0.313 -0.0288 -2.56 -3.8675 -0.9979 1941078 CBMicro_031026 COc1ccc(/C=N/N2C(=O)CSC2=S)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P09 compound treatment 0.34 -0.0021 -0.17 0.335 -0.00684 -0.61 -0.5516 -0.8748 1941079 CBMicro_031027 Cc1cc(C)nc(SCC(=O)Nc2ccccc2C)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P10 compound treatment 0.35 0.0079 0.66 0.342 1.61E-4 0.01 0.4741 0.7223 1209000 CBMicro_031028 CCOC(=O)c1sc(NC(=O)CCOc2ccccc2)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P11 compound treatment 0.333 -0.0091 -0.76 0.331 -0.0108 -0.96 -1.2132 -0.9929 1941080 CBMicro_031029 CCCNC(=O)c1sc2ccccc2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P12 compound treatment 0.349 0.0069 0.57 0.346 0.00416 0.37 0.666 0.9773 1941081 CBMicro_031030 Fc1c(F)c(F)c(C(=O)NCC2CCN(CC2)C(=O)c3c(F)c(F)c(F)c(F)c3F)c(F)c1F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P13 compound treatment 0.335 -0.0071 -0.59 0.335 -0.00684 -0.61 -0.8452 -0.9999 1565433 CBMicro_031031 Cc1cc(C)nc(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P14 compound treatment 0.337 -0.0051 -0.42 0.336 -0.00584 -0.52 -0.6651 -0.995 1941082 CBMicro_031032 Nc1cc(O)nc(SCc2ccccc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P15 compound treatment 0.337 -0.0051 -0.42 0.337 -0.00484 -0.43 -0.6024 -1.0 1145504 CBMicro_031033 CCOc1ccc(NC2OC(=O)c3c2ccc(OC)c3OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P16 compound treatment 0.464 0.122 10.12 0.464 0.122 10.83 14.8114 0.9994 1941083 CBMicro_031034 CN(C)c1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P17 compound treatment 0.316 -0.0261 -2.17 0.317 -0.0248 -2.2 -3.0885 -1.0 1570769 CBMicro_031035 CCOc1ccc(cc1)N2C(=O)CC(Sc3ccccc3C(=O)O)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P18 compound treatment 0.333 -0.0091 -0.76 0.328 -0.0138 -1.23 -1.4012 -0.9729 1493400 CBMicro_031036 Cc1onc(c1C(=O)Nc2ccccc2F)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P19 compound treatment 0.368 0.0259 2.15 0.391 0.0492 4.36 4.6013 0.947 1864169 CBMicro_031037 Oc1ccc2ccccc2c1C(NC(=O)COc3ccccc3[N+](=O)[O-])c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P20 compound treatment 0.348 0.0059 0.49 0.348 0.00616 0.55 0.7326 0.9985 1085880 CBMicro_031038 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2Cl)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P21 compound treatment 0.355 0.0129 1.07 0.36 0.0182 1.61 1.8955 0.9804 1646911 CBMicro_031039 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)CC5CCCO5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P22 compound treatment 0.344 0.0019 0.16 0.341 -8.39E-4 -0.07 0.0592 0.3388 1729004 CBMicro_031040 Cc1c[nH]c2c(cc(C)cc12)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P23 positive control 0.093 -0.249 -20.68 0.092 -0.25 -22.14 -30.279 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.782 P24 positive control 0.097 -0.245 -20.35 0.097 -0.245 -21.7 -29.7308 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A01 mock treatment 0.334 -0.0071 -0.59 0.344 0.00142 0.13 -0.3277 -0.5439 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A02 mock treatment 0.351 0.0099 0.82 0.349 0.00642 0.57 0.9836 0.9838 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A03 compound treatment 0.376 0.0349 2.9 0.372 0.0294 2.61 3.8925 0.9986 1941084 CBMicro_031041 COc1cccc(C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A04 compound treatment 0.214 -0.127 -10.55 0.258 -0.0846 -7.5 -12.7613 -0.986 1941085 CBMicro_031042 COC(=O)CCN1C(=O)/C(=C\C=C\c2ccccc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A05 compound treatment 0.334 -0.0071 -0.59 0.344 0.00142 0.13 -0.3277 -0.5439 1941086 CBMicro_031043 [O-][N+](=O)c1ccc(cc1)/C(=N\OC(=O)c2cccc(F)c2)/c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A06 compound treatment 0.326 -0.0151 -1.25 0.331 -0.0116 -1.03 -1.6119 -0.9951 1941087 CBMicro_031044 [O-][N+](=O)c1cccc(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A07 compound treatment 0.331 -0.0101 -0.84 0.337 -0.00558 -0.49 -0.9424 -0.9683 1941088 CBMicro_031045 O=C(NCCSc1ccccn1)/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A08 compound treatment 0.329 -0.0121 -1.0 0.334 -0.00858 -0.76 -1.2478 -0.9906 1941089 CBMicro_031046 [O-][N+](=O)c1ccc(COc2ccc3c4CCCc4c(=O)oc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A09 compound treatment 0.332 -0.0091 -0.76 0.334 -0.00858 -0.76 -1.0717 -1.0 1189961 CBMicro_031047 O=C(N1CCCC1)c2cc3ccccc3oc2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A10 compound treatment 0.331 -0.0101 -0.84 0.335 -0.00758 -0.67 -1.0678 -0.994 1479284 CBMicro_031048 CC(C)Oc1cc2oc(=O)c3CCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A11 compound treatment 0.343 0.0019 0.16 0.343 4.19E-4 0.04 0.138 0.8502 1941090 CBMicro_031049 [O-][N+](=O)c1cc(ccc1Sc2nnnn2c3ccccc3)n4cnnn4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A12 compound treatment 0.339 -0.0021 -0.17 0.343 4.19E-4 0.04 -0.0968 -0.5439 1733336 CBMicro_031050 Cc1c(Cc2ccccc2)c(=O)oc3cc(OCC(=O)C(C)(C)C)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A13 compound treatment 0.347 0.0059 0.49 0.352 0.00942 0.83 0.9368 0.9678 1941091 CBMicro_031051 Cc1ccc(NC(=O)Cc2ccc(Br)cc2)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A14 compound treatment 0.341 -9.68E-5 -0.01 0.344 0.00142 0.13 0.0833 0.6606 1941092 CBMicro_031052 O=C(CSc1nnc(c2cccs2)n1c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A15 compound treatment 0.345 0.0039 0.32 0.344 0.00142 0.13 0.3181 0.9151 1624886 CBMicro_031053 Clc1cccc(OCC(=O)NCCc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A16 compound treatment 0.347 0.0059 0.49 0.347 0.00442 0.39 0.6235 0.9938 1941093 CBMicro_031054 O=C(CCCOc1ccccc1)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A17 compound treatment 0.351 0.0099 0.82 0.353 0.0104 0.92 1.2343 0.9983 1941094 CBMicro_031055 Fc1ccc(N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4ccc(Br)cc4)c(F)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A18 compound treatment 0.335 -0.0061 -0.51 0.335 -0.00758 -0.67 -0.8329 -0.9903 1941095 CBMicro_031056 Cc1cccc(NC(=O)CCCOc2ccccc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A19 compound treatment 0.345 0.0039 0.32 0.347 0.00442 0.39 0.5061 0.9956 1941096 CBMicro_031057 COc1cc(NC(=O)CCCOc2ccccc2)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A20 compound treatment 0.345 0.0039 0.32 0.345 0.00242 0.21 0.3807 0.9799 1587750 CBMicro_031058 COc1ccc(cc1OC)c2csc(N)c2C(=O)OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A21 compound treatment 0.331 -0.0101 -0.84 0.334 -0.00858 -0.76 -1.1304 -0.9988 1690320 CBMicro_031059 Cc1cccc(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A22 compound treatment 0.336 -0.0051 -0.42 0.339 -0.00358 -0.32 -0.5236 -0.9899 1400632 CBMicro_031060 CCOC(=O)c1c(NC(=O)c2ccccc2F)sc3CC(C)CCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A23 positive control 0.083 -0.258 -21.43 0.085 -0.258 -22.83 -31.2924 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 A24 positive control 0.085 -0.256 -21.26 0.086 -0.257 -22.74 -31.1124 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B01 mock treatment 0.336 -0.0051 -0.42 0.336 -0.00658 -0.58 -0.7116 -0.9876 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B02 mock treatment 0.347 0.0059 0.49 0.342 -5.81E-4 -0.05 0.3102 0.6294 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B03 compound treatment 0.333 -0.0081 -0.67 0.336 -0.00658 -0.58 -0.8877 -0.9975 1478087 CBMicro_031061 Fc1ccc(cc1)N(CC(=O)N2CCCC2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B04 compound treatment 0.335 -0.0061 -0.51 0.341 -0.00158 -0.14 -0.457 -0.8701 1375927 CBMicro_031062 CCc1cc(=O)oc2cc(OCC(=O)O)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B05 compound treatment 0.327 -0.0141 -1.17 0.332 -0.0106 -0.94 -1.4906 -0.994 1941097 CBMicro_031063 CCn1c2ccccc2c3cc(/C=N/N4CCN(CC4)c5ccccc5OC)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B06 compound treatment 0.328 -0.0131 -1.09 0.333 -0.00958 -0.85 -1.3692 -0.9925 1941098 CBMicro_031064 COc1ccc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B07 compound treatment 0.333 -0.0081 -0.67 0.339 -0.00358 -0.32 -0.6997 -0.9413 1941099 CBMicro_031065 COCCNc1ncnc2ccc(Br)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B08 compound treatment 0.329 -0.0121 -1.0 0.334 -0.00858 -0.76 -1.2478 -0.9906 1941100 CBMicro_031066 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccccc3[N+](=O)[O-])cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B09 compound treatment 0.325 -0.0161 -1.34 0.327 -0.0156 -1.38 -1.9213 -0.9999 1400363 CBMicro_031067 CCCc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B10 compound treatment 0.33 -0.0111 -0.92 0.332 -0.0106 -0.94 -1.3145 -1.0 1403331 CBMicro_031068 COC(=O)c1ccc(COc2cc3oc(=O)cc(c4ccccc4)c3cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B11 compound treatment 0.342 9.03E-4 0.07 0.341 -0.00158 -0.14 -0.046 -0.2897 1670549 CBMicro_031069 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)NCc3ccco3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B12 compound treatment 0.33 -0.0111 -0.92 0.333 -0.00958 -0.85 -1.2518 -0.9992 1941101 CBMicro_031070 O=C(CCCOc1ccccc1)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B13 compound treatment 0.328 -0.0131 -1.09 0.329 -0.0136 -1.2 -1.6199 -0.9987 1236394 CBMicro_031071 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3cc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B14 compound treatment 0.332 -0.0091 -0.76 0.332 -0.0106 -0.94 -1.197 -0.9942 1705307 CBMicro_031072 Cc1ccccc1OCC(=O)NCc2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B15 compound treatment 0.34 -0.0011 -0.09 0.335 -0.00758 -0.67 -0.5394 -0.7957 1432256 CBMicro_031073 CCN(CC)c1ccc(NC(=O)COc2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B16 compound treatment 0.333 -0.0081 -0.67 0.331 -0.0116 -1.03 -1.201 -0.979 1941102 CBMicro_031074 COc1ccc(cc1)C(=O)NCCSc2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B17 compound treatment 0.339 -0.0021 -0.17 0.339 -0.00358 -0.32 -0.3475 -0.96 1643371 CBMicro_031075 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3Cc5ccco5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B18 compound treatment 0.337 -0.0041 -0.34 0.337 -0.00558 -0.49 -0.5902 -0.9833 1941103 CBMicro_031076 Cc1cccc(OCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B19 compound treatment 0.336 -0.0051 -0.42 0.334 -0.00858 -0.76 -0.8369 -0.9617 1941104 CBMicro_031077 O=C(CCCOc1ccccc1)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B20 compound treatment 0.335 -0.0061 -0.51 0.338 -0.00458 -0.41 -0.6449 -0.994 1784499 CBMicro_031078 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccccc2[N+](=O)[O-])c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B21 compound treatment 0.34 -0.0011 -0.09 0.34 -0.00258 -0.23 -0.2261 -0.9185 1941105 CBMicro_031079 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cc(OC)ccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B22 compound treatment 0.33 -0.0111 -0.92 0.331 -0.0116 -1.03 -1.3771 -0.9985 1941106 CBMicro_031080 Fc1ccccc1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B23 positive control 0.083 -0.258 -21.43 0.083 -0.26 -23.0 -31.4178 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 B24 positive control 0.089 -0.252 -20.93 0.085 -0.258 -22.83 -30.9402 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C01 mock treatment 0.344 0.0029 0.24 0.344 0.00142 0.13 0.2594 0.954 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C02 mock treatment 0.348 0.0069 0.57 0.362 0.0194 1.72 1.6222 0.8943 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C03 compound treatment 0.3 -0.0411 -3.41 0.305 -0.0376 -3.33 -4.7675 -0.9999 1941107 CBMicro_031081 CN1C(=O)N(C)C2(N(N)C(=N)NC12c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C04 compound treatment 0.344 0.0029 0.24 0.345 0.00242 0.21 0.322 0.9983 1941108 CBMicro_031082 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CCCOc3ccc(Cl)cc3Cl)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C05 compound treatment 0.337 -0.0041 -0.34 0.343 4.19E-4 0.04 -0.2142 -0.6261 1941109 CBMicro_031083 CN1C(=O)/C(=N\OC(=O)c2cccc(F)c2)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C06 compound treatment 0.341 -9.68E-5 -0.01 0.353 0.0104 0.92 0.6472 0.7009 1941110 CBMicro_031084 COC(=O)CCN1C(=O)/C(=C\c2ccc(C)cc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C07 compound treatment 0.339 -0.0021 -0.17 0.34 -0.00258 -0.23 -0.2848 -0.9909 1237785 CBMicro_031085 O=C1CC(Nc2ccccc2)C(=O)N1c3ccc(cc3)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C08 compound treatment 0.333 -0.0081 -0.67 0.336 -0.00658 -0.58 -0.8877 -0.9975 1333423 CBMicro_031086 CC(C)Oc1ccc2c(cc(=O)oc2c1C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C09 compound treatment 0.332 -0.0091 -0.76 0.339 -0.00358 -0.32 -0.7584 -0.9258 1941111 CBMicro_031087 COc1ccccc1CNC(=O)/C=C/c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C10 compound treatment 0.339 -0.0021 -0.17 0.341 -0.00158 -0.14 -0.2221 -0.9942 1436255 CBMicro_031088 CC(C)(C)C(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C11 compound treatment 0.337 -0.0041 -0.34 0.34 -0.00258 -0.23 -0.4022 -0.9814 1549687 CBMicro_031089 CCc1cccc(C)c1NC(=O)COc2ccc(C)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C12 compound treatment 0.332 -0.0091 -0.76 0.336 -0.00658 -0.58 -0.9464 -0.9918 1260591 CBMicro_031090 Cc1cc(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C13 compound treatment 0.338 -0.0031 -0.26 0.338 -0.00458 -0.41 -0.4688 -0.9757 1324645 CBMicro_031091 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C14 compound treatment 0.342 9.03E-4 0.07 0.339 -0.00358 -0.32 -0.1714 -0.5255 1941112 CBMicro_031092 OCCN1CCN(CC1)C(=O)CSc2nnc(CCCN3C(=O)c4cccc5cccc(C3=O)c45)n2c6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C15 compound treatment 0.339 -0.0021 -0.17 0.336 -0.00658 -0.58 -0.5355 -0.8798 1491689 CBMicro_031093 CCOC(=O)c1c(NC(=O)C2CCCN2S(=O)(=O)c3ccc(Cl)cc3)scc1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C16 compound treatment 0.341 -9.68E-5 -0.01 0.338 -0.00458 -0.41 -0.2927 -0.721 1560672 CBMicro_031094 COc1ccccc1Nc2ncnc3ccc(Br)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C17 compound treatment 0.363 0.0219 1.82 0.362 0.0194 1.72 2.5027 0.9996 1941113 CBMicro_031095 O=C(Oc1ccc(/C=C/C(=O)c2ccccc2)cc1)c3cccnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C18 compound treatment 0.323 -0.0181 -1.5 0.326 -0.0166 -1.47 -2.1014 -0.9999 1941114 CBMicro_031096 Cc1ccc(OCC(=O)Oc2ccc(Cl)cc2C)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C19 compound treatment 0.338 -0.0031 -0.26 0.336 -0.00658 -0.58 -0.5942 -0.9323 1414272 CBMicro_031097 Cc1nc2c(ccc3ccccc32)c(O)c1CN4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C20 compound treatment 0.334 -0.0071 -0.59 0.333 -0.00958 -0.85 -1.017 -0.9841 1623386 CBMicro_031098 CCCC1CCc2c(C(=O)N)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C21 compound treatment 0.332 -0.0091 -0.76 0.34 -0.00258 -0.23 -0.6957 -0.8817 1625620 CBMicro_031099 COc1ccc(CCN2C(=O)C3C(C2=O)C4(C)c5ccccc5C3c6ccccc64)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C22 compound treatment 0.344 0.0029 0.24 0.343 4.19E-4 0.04 0.1967 0.8066 1199278 CBMicro_031100 CCOc1ccc(NC(=O)c2ccoc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C23 positive control 0.082 -0.259 -21.51 0.083 -0.26 -23.0 -31.4765 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 C24 positive control 0.087 -0.254 -21.09 0.087 -0.256 -22.65 -30.9323 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D01 mock treatment 0.341 -9.68E-5 -0.01 0.344 0.00142 0.13 0.0833 0.6606 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D02 mock treatment 0.346 0.0049 0.41 0.347 0.00442 0.39 0.5648 0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D03 compound treatment 0.342 9.03E-4 0.07 0.342 -5.81E-4 -0.05 0.0166 0.1829 1472566 CBMicro_031101 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)Nc3cc(Cl)ccc3C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D04 compound treatment 0.336 -0.0051 -0.42 0.339 -0.00358 -0.32 -0.5236 -0.9899 1267993 CBMicro_031102 COc1cc(NC(=O)COc2cccc(C)c2C)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D05 compound treatment 0.34 -0.0011 -0.09 0.343 4.19E-4 0.04 -0.0381 -0.3875 1941115 CBMicro_031103 Cc1c(NS(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-])c(=O)n(c3ccccc3)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D06 compound treatment 0.342 9.03E-4 0.07 0.341 -0.00158 -0.14 -0.046 -0.2897 1941116 CBMicro_031104 COc1cc(cc(OC)c1OC)C(=O)N/C(=C/c2ccc(Br)cc2)/C(=O)NCCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D07 compound treatment 0.381 0.0399 3.31 0.383 0.0404 3.58 4.8753 0.9992 1941117 CBMicro_031105 CCN(CC)Cc1c(O)ccc2c(=O)c(Oc3ccccc3Br)c(oc12)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D08 compound treatment 0.34 -0.0011 -0.09 0.343 4.19E-4 0.04 -0.0381 -0.3875 1941118 CBMicro_031106 COc1ccc(NC(=O)CCCOc2ccccc2)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D09 compound treatment 0.351 0.0099 0.82 0.352 0.00942 0.83 1.1716 1.0 1730184 CBMicro_031107 CCc1cc(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D10 compound treatment 0.337 -0.0041 -0.34 0.338 -0.00458 -0.41 -0.5275 -0.9961 1171166 CBMicro_031108 CC(=C)COc1cc2oc(=O)cc(C)c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D11 compound treatment 0.345 0.0039 0.32 0.348 0.00542 0.48 0.5687 0.9817 1941119 CBMicro_031109 COc1cccc(NC(=O)C2C3CCC4C(CCC23)C4(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D12 compound treatment 0.402 0.0609 5.06 0.397 0.0544 4.82 6.9854 0.9997 1941120 CBMicro_031110 Cc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D13 compound treatment 0.337 -0.0041 -0.34 0.34 -0.00258 -0.23 -0.4022 -0.9814 1941121 CBMicro_031111 O=C(CCCOc1ccccc1)Nc2nnc[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D14 compound treatment 0.318 -0.0231 -1.92 0.324 -0.0186 -1.65 -2.5202 -0.9971 1941122 CBMicro_031112 Cc1ccc(SCCNS(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D15 compound treatment 0.361 0.0199 1.65 0.361 0.0184 1.63 2.3226 1.0 1321362 CBMicro_031113 Cc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)N)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D16 compound treatment 0.334 -0.0071 -0.59 0.331 -0.0116 -1.03 -1.1423 -0.9653 1701856 CBMicro_031114 CC(C)(C)c1ccc(cc1)N2C(=O)CC(=O)NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D17 compound treatment 0.338 -0.0031 -0.26 0.336 -0.00658 -0.58 -0.5942 -0.9323 1258281 CBMicro_031115 CN(C)CCNc1ncnc2ccc(Br)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D18 compound treatment 0.397 0.0559 4.64 0.412 0.0694 6.15 7.6319 0.9903 1941123 CBMicro_031116 CCc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D19 compound treatment 0.34 -0.0011 -0.09 0.339 -0.00358 -0.32 -0.2888 -0.8747 1941124 CBMicro_031117 CC(=O)c1cccc(NC(=O)COc2ccc(C)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D20 compound treatment 0.336 -0.0051 -0.42 0.336 -0.00658 -0.58 -0.7116 -0.9876 1188277 CBMicro_031118 Brc1ccc2ncnc(NCc3ccco3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D21 compound treatment 0.332 -0.0091 -0.76 0.344 0.00142 0.13 -0.4451 -0.5813 1941125 CBMicro_031119 COc1ccc(cc1)c2nnc(SCC(=O)c3ccccc3)[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D22 compound treatment 0.328 -0.0131 -1.09 0.319 -0.0236 -2.09 -2.2465 -0.9537 1312514 CBMicro_031120 Brc1ccc2ncnc(NCCN3CCOCC3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D23 positive control 0.083 -0.258 -21.43 0.083 -0.26 -23.0 -31.4178 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 D24 positive control 0.088 -0.253 -21.01 0.089 -0.254 -22.47 -30.7483 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E01 mock treatment 0.333 -0.0081 -0.67 0.335 -0.00758 -0.67 -0.9503 -1.0 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E02 mock treatment 0.345 0.0039 0.32 0.346 0.00342 0.3 0.4434 0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E03 compound treatment 0.352 0.0109 0.91 0.352 0.00942 0.83 1.2303 0.9992 1941126 CBMicro_031121 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc(Cl)c1OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E04 compound treatment 0.333 -0.0081 -0.67 0.339 -0.00358 -0.32 -0.6997 -0.9413 1941127 CBMicro_031122 COC(=O)CN1C(=O)/C(=C\c2ccccc2F)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E05 compound treatment 0.325 -0.0161 -1.34 0.333 -0.00958 -0.85 -1.5453 -0.976 1941128 CBMicro_031123 COc1ccc2/C(=N/OC(=O)c3cccc4ccccc34)/CCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E06 compound treatment 0.332 -0.0091 -0.76 0.331 -0.0116 -1.03 -1.2597 -0.9886 1162833 CBMicro_031124 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E07 compound treatment 0.341 -9.68E-5 -0.01 0.345 0.00242 0.21 0.1459 0.6801 1941129 CBMicro_031125 CCSc1nc2ccccc2n1C(=O)/C=C/c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E08 compound treatment 0.339 -0.0021 -0.17 0.339 -0.00358 -0.32 -0.3475 -0.96 1408226 CBMicro_031126 CC(C)Oc1ccc2c3CCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E09 compound treatment 0.34 -0.0011 -0.09 0.344 0.00142 0.13 0.0246 0.1582 1128282 CBMicro_031127 Cc1occc1C(=O)N2CCc3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E10 compound treatment 0.331 -0.0101 -0.84 0.346 0.00342 0.3 -0.3784 -0.4246 1941130 CBMicro_031128 CC(C)Oc1ccc2c(C)c(C)c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E11 compound treatment 0.335 -0.0061 -0.51 0.331 -0.0116 -1.03 -1.0836 -0.9469 1503420 CBMicro_031129 CC(Oc1ccc(Cl)cc1)C(=O)n2nc(C)cc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E12 compound treatment 0.339 -0.0021 -0.17 0.342 -5.81E-4 -0.05 -0.1595 -0.8786 1303022 CBMicro_031130 Cc1c(Cc2ccccc2)c(=O)oc3c(C)c(OCC(=O)C(C)(C)C)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E13 compound treatment 0.335 -0.0061 -0.51 0.345 0.00242 0.21 -0.2063 -0.3753 1785982 CBMicro_031131 COc1ccc(cc1NC(=O)Cc2ccc(Br)cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E14 compound treatment 0.342 9.03E-4 0.07 0.337 -0.00558 -0.49 -0.2967 -0.5931 1941131 CBMicro_031132 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCn6ccnc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E15 compound treatment 0.337 -0.0041 -0.34 0.34 -0.00258 -0.23 -0.4022 -0.9814 1124306 CBMicro_031133 O=c1n(CC2CCCO2)c(=O)c3ccccc3c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E16 compound treatment 0.338 -0.0031 -0.26 0.337 -0.00558 -0.49 -0.5315 -0.9535 1294709 CBMicro_031134 CCc1cc(=O)oc2cc(OCC(=C)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E17 compound treatment 0.367 0.0259 2.15 0.345 0.00242 0.21 1.6722 0.7738 1941132 CBMicro_031135 COc1ccc(cc1OC)C(=O)O/N=C(\c2ccncc2)/c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E18 compound treatment 0.341 -9.68E-5 -0.01 0.341 -0.00158 -0.14 -0.1047 -0.7464 1537511 CBMicro_031136 Clc1ccc(cc1)C(=O)COc2cc3oc(=O)cc(c4ccccc4)c3cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E19 compound treatment 0.34 -0.0011 -0.09 0.333 -0.00958 -0.85 -0.6648 -0.7785 1941133 CBMicro_031137 CC(=O)c1cnc2cc(nn2c1C)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E20 compound treatment 0.329 -0.0121 -1.0 0.339 -0.00358 -0.32 -0.9345 -0.8873 1253456 CBMicro_031138 CCCOC(=O)c1c(N)scc1c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E21 compound treatment 0.333 -0.0081 -0.67 0.325 -0.0176 -1.56 -1.577 -0.9294 1941134 CBMicro_031139 Nc1cc(nn1Cc2ccc(Cl)cc2)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E22 compound treatment 0.331 -0.0101 -0.84 0.332 -0.0106 -0.94 -1.2558 -0.9984 1515830 CBMicro_031140 Ic1ccccc1NC(=O)COc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E23 positive control 0.083 -0.258 -21.43 0.084 -0.259 -22.92 -31.3551 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 E24 positive control 0.089 -0.252 -20.93 0.089 -0.254 -22.47 -30.6896 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F01 mock treatment 0.338 -0.0031 -0.26 0.339 -0.00358 -0.32 -0.4062 -0.9945 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F02 mock treatment 0.341 -9.68E-5 -0.01 0.341 -0.00158 -0.14 -0.1047 -0.7464 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F03 compound treatment 0.302 -0.0391 -3.25 0.316 -0.0266 -2.36 -3.9608 -0.9876 1941135 CBMicro_031141 NC(=O)/C=C\C(=O)Nc1cccc(c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F04 compound treatment 0.374 0.0329 2.73 0.375 0.0324 2.87 3.9631 0.9997 1941136 CBMicro_031142 COc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3cccc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F05 compound treatment 0.329 -0.0121 -1.0 0.339 -0.00358 -0.32 -0.9345 -0.8873 1941137 CBMicro_031143 Ic1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F06 compound treatment 0.331 -0.0101 -0.84 0.338 -0.00458 -0.41 -0.8798 -0.9446 1675709 CBMicro_031144 CC1CCc2c(C(=O)N)c(NC(=O)COc3ccc(Cl)cc3C)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F07 compound treatment 0.334 -0.0071 -0.59 0.339 -0.00358 -0.32 -0.641 -0.9579 1941138 CBMicro_031145 FC(F)(F)c1ccccc1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F08 compound treatment 0.377 0.0359 2.98 0.401 0.0584 5.18 5.7685 0.9656 1941139 CBMicro_031146 COc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F09 compound treatment 0.339 -0.0021 -0.17 0.339 -0.00358 -0.32 -0.3475 -0.96 1941140 CBMicro_031147 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)NC(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F10 compound treatment 0.316 -0.0251 -2.08 0.33 -0.0126 -1.11 -2.2616 -0.9571 1304499 CBMicro_031148 CC(C)Oc1ccc2c3ccccc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F11 compound treatment 0.342 9.03E-4 0.07 0.342 -5.81E-4 -0.05 0.0166 0.1829 1941141 CBMicro_031149 C/C(=N\N1CCN(Cc2ccc(Cl)cc2)CC1)/c3ccc(O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F12 compound treatment 0.359 0.0179 1.49 0.361 0.0184 1.63 2.2052 0.9989 1187021 CBMicro_031150 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3cccc(C)c3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F13 compound treatment 0.325 -0.0161 -1.34 0.328 -0.0146 -1.29 -1.8586 -0.9999 1941142 CBMicro_031151 Brc1cccc(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F14 compound treatment 0.384 0.0429 3.56 0.387 0.0444 3.94 5.3021 0.9988 1200354 CBMicro_031152 COC(=O)c1ccc(NC(=O)C2(C)CC3c4ccccc4C2c5ccccc35)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F15 compound treatment 0.347 0.0059 0.49 0.346 0.00342 0.3 0.5608 0.9733 1313299 CBMicro_031153 Fc1ccc(cc1)C(=O)COc2ccc3c(c2)oc(=O)c4ccccc43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F16 compound treatment 0.344 0.0029 0.24 0.34 -0.00258 -0.23 0.0087 0.0262 1941143 CBMicro_031154 CC(C)Oc1ccc(/C=N/N=C/c2ccc(OC(C)C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F17 compound treatment 0.349 0.0079 0.66 0.35 0.00742 0.66 0.9289 1.0 1676770 CBMicro_031155 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CCN2C(=O)c3ccccc3C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F18 compound treatment 0.358 0.0169 1.4 0.358 0.0154 1.37 1.9585 0.9999 1941144 CBMicro_031156 O=C(CCCOc1ccccc1)Nc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F19 compound treatment 0.358 0.0169 1.4 0.34 -0.00258 -0.23 0.8306 0.5842 1492115 CBMicro_031157 COC(=O)c1cccc(NC(=O)COc2cccc(C)c2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F20 compound treatment 0.335 -0.0061 -0.51 0.342 -5.81E-4 -0.05 -0.3943 -0.775 1941145 CBMicro_031158 CCOc1ccccc1/C=C\2/SC(=S)N(CC(=O)OC)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F21 compound treatment 0.337 -0.0041 -0.34 0.339 -0.00358 -0.32 -0.4649 -0.9994 1651163 CBMicro_031159 Cc1c(Cl)cccc1NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F22 compound treatment 0.337 -0.0041 -0.34 0.34 -0.00258 -0.23 -0.4022 -0.9814 1941146 CBMicro_031160 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CCCOc3ccccc3)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F23 positive control 0.086 -0.255 -21.18 0.088 -0.255 -22.56 -30.9283 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 F24 positive control 0.091 -0.25 -20.76 0.091 -0.252 -22.3 -30.4468 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G01 mock treatment 0.328 -0.0131 -1.09 0.335 -0.00758 -0.67 -1.2439 -0.9732 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G02 mock treatment 0.335 -0.0061 -0.51 0.338 -0.00458 -0.41 -0.6449 -0.994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G03 compound treatment 0.326 -0.0151 -1.25 0.357 0.0144 1.28 0.0174 0.0097 1941147 CBMicro_031161 C/C(=C\C(=O)c1ccc(Cl)cc1)/Nc2ccc(Br)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G04 compound treatment 0.345 0.0039 0.32 0.354 0.0114 1.01 0.9447 0.8891 1490607 CBMicro_031162 Cc1ccc(cc1)c2ccc(OCC(=O)N3CCOCC3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G05 compound treatment 0.335 -0.0061 -0.51 0.363 0.0204 1.81 0.9217 0.4905 1941148 CBMicro_031163 COc1ccccc1C(=O)O/N=C(/c2ccncc2)\c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G06 compound treatment 0.337 -0.0041 -0.34 0.353 0.0104 0.92 0.4124 0.4191 1941149 CBMicro_031164 CCCCOc1ccc(NC(=O)COc2cccc(C)c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G07 compound treatment 0.455 0.114 9.46 0.481 0.138 12.27 15.3606 0.9917 1941150 CBMicro_031165 CN(C)c1ccc(/C=N/S(=O)(=O)CCc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G08 compound treatment 0.329 -0.0121 -1.0 0.343 4.19E-4 0.04 -0.6838 -0.6805 1695739 CBMicro_031166 COC(=O)c1ccc(COc2ccc3c(cc(=O)oc3c2C)c4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G09 compound treatment 0.323 -0.0181 -1.5 0.344 0.00142 0.13 -0.9734 -0.6456 1282985 CBMicro_031167 CC(Oc1ccccc1)C(=O)Nc2ccccc2I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G10 compound treatment 0.336 -0.0051 -0.42 0.337 -0.00558 -0.49 -0.6489 -0.997 1535970 CBMicro_031168 CC(C)Oc1cc(C)cc2oc(=O)c3CCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G11 compound treatment 0.324 -0.0171 -1.42 0.335 -0.00758 -0.67 -1.4787 -0.9416 1085460 CBMicro_031169 Clc1cccc(OCC(=O)NCc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G12 compound treatment 0.333 -0.0081 -0.67 0.353 0.0104 0.92 0.1776 0.1555 1546914 CBMicro_031170 CC(C)(C)C(=O)COc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G13 compound treatment 0.334 -0.0071 -0.59 0.336 -0.00658 -0.58 -0.829 -1.0 1941151 CBMicro_031171 [O-][N+](=O)c1ccc(Cl)c(NC(=O)Cc2ccc(Br)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G14 compound treatment 0.335 -0.0061 -0.51 0.345 0.00242 0.21 -0.2063 -0.3753 1941152 CBMicro_031172 CCOc1ccccc1NC(=O)C2C(c3ccccc3)C2(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G15 compound treatment 0.334 -0.0071 -0.59 0.336 -0.00658 -0.58 -0.829 -1.0 1653364 CBMicro_031173 O=Cc1ccc(OC(=O)c2cccnc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G16 compound treatment 0.331 -0.0101 -0.84 0.343 4.19E-4 0.04 -0.5664 -0.6751 1571815 CBMicro_031174 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccccc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G17 compound treatment 0.355 0.0139 1.15 0.359 0.0164 1.46 1.8451 0.9934 1941153 CBMicro_031175 COc1ccccc1C(=O)O/N=C\2/C(=O)N(C)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G18 compound treatment 0.575 0.234 19.42 0.586 0.243 21.57 28.9848 0.9986 1941154 CBMicro_031176 CC(N1C(=O)/C(=C\c2ccc(F)cc2)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G19 compound treatment 0.331 -0.0101 -0.84 0.334 -0.00858 -0.76 -1.1304 -0.9988 1941155 CBMicro_031177 Cc1ccccc1CNC(=O)c2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G20 compound treatment 0.341 -9.68E-5 -0.01 0.353 0.0104 0.92 0.6472 0.7009 1697006 CBMicro_031178 Fc1ccc(cc1)C(=O)CNC(=O)c2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G21 compound treatment 0.343 0.0019 0.16 0.338 -0.00458 -0.41 -0.1753 -0.4025 1941156 CBMicro_031179 CCOC(=O)c1sc2nc(NC(=O)c3ccc(cc3)[N+](=O)[O-])sc(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G22 compound treatment 0.332 -0.0091 -0.76 0.338 -0.00458 -0.41 -0.8211 -0.9576 1941157 CBMicro_031180 CN1C(=O)/C(=N/OC(=O)c2ccccc2F)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G23 positive control 0.086 -0.255 -21.18 0.089 -0.254 -22.47 -30.8657 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 G24 positive control 0.092 -0.249 -20.68 0.095 -0.248 -21.94 -30.1375 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H01 mock treatment 0.332 -0.0091 -0.76 0.333 -0.00958 -0.85 -1.1344 -0.9983 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H02 mock treatment 0.346 0.0049 0.41 0.348 0.00542 0.48 0.6274 0.9966 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H03 compound treatment 0.327 -0.0141 -1.17 0.334 -0.00858 -0.76 -1.3652 -0.9782 1941158 CBMicro_031181 FC(F)(F)c1ccc2SC(CC(=O)Nc3ccccc3)C(=O)Nc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H04 compound treatment 0.328 -0.0131 -1.09 0.333 -0.00958 -0.85 -1.3692 -0.9925 1151802 CBMicro_031182 CCc1cc(=O)oc2cc(OCc3ccc(F)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H05 compound treatment 0.341 -9.68E-5 -0.01 0.339 -0.00358 -0.32 -0.2301 -0.7248 1941159 CBMicro_031183 CCOC(=O)C1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H06 compound treatment 0.329 -0.0121 -1.0 0.337 -0.00558 -0.49 -1.0598 -0.9468 1386086 CBMicro_031184 Cc1cccc(OCC(=O)Nc2ccc(I)cc2C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H07 compound treatment 0.332 -0.0091 -0.76 0.335 -0.00758 -0.67 -1.0091 -0.9983 1722576 CBMicro_031185 CC(C)CNc1ncnc2ccc(Br)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H08 compound treatment 0.332 -0.0091 -0.76 0.338 -0.00458 -0.41 -0.8211 -0.9576 1617531 CBMicro_031186 CCc1cc(=O)oc2cc(OCC(=O)OC(C)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H09 compound treatment 0.389 0.0479 3.98 0.402 0.0594 5.27 6.5356 0.9904 1941160 CBMicro_031187 COC(=O)CCN1C(=O)/C(=C\c2ccc(F)cc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H10 compound treatment 0.337 -0.0041 -0.34 0.334 -0.00858 -0.76 -0.7782 -0.9342 1941161 CBMicro_031188 CC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H11 compound treatment 0.338 -0.0031 -0.26 0.338 -0.00458 -0.41 -0.4688 -0.9757 1576431 CBMicro_031189 Fc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H12 compound treatment 0.328 -0.0131 -1.09 0.33 -0.0126 -1.11 -1.5572 -0.9999 1785435 CBMicro_031190 [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H13 compound treatment 0.363 0.0219 1.82 0.361 0.0184 1.63 2.44 0.9986 1941162 CBMicro_031191 COc1cccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Cl)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H14 compound treatment 0.333 -0.0081 -0.67 0.331 -0.0116 -1.03 -1.201 -0.979 1589662 CBMicro_031192 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(I)cc5)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H15 compound treatment 0.34 -0.0011 -0.09 0.34 -0.00258 -0.23 -0.2261 -0.9185 1150679 CBMicro_031193 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2cccc(Cl)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H16 compound treatment 0.332 -0.0091 -0.76 0.331 -0.0116 -1.03 -1.2597 -0.9886 1941163 CBMicro_031194 COc1ccc(/C=N/N2CCN(Cc3ccc(C)cc3)CC2)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H17 compound treatment 0.342 9.03E-4 0.07 0.342 -5.81E-4 -0.05 0.0166 0.1829 1706844 CBMicro_031195 CCc1cc(=O)oc2cc(OCc3ccccc3Cl)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H18 compound treatment 0.345 0.0039 0.32 0.342 -5.81E-4 -0.05 0.1927 0.5875 1941164 CBMicro_031196 COC(=O)CCN1C(=O)/C(=C/c2cccc(OCc3ccccc3)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H19 compound treatment 0.353 0.0119 0.99 0.34 -0.00258 -0.23 0.537 0.5295 1941165 CBMicro_031197 CC(=O)c1cccc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H20 compound treatment 0.33 -0.0111 -0.92 0.332 -0.0106 -0.94 -1.3145 -1.0 1941166 CBMicro_031198 Brc1ccc2ncnc(NCCCN3CCOCC3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H21 compound treatment 0.328 -0.0131 -1.09 0.333 -0.00958 -0.85 -1.3692 -0.9925 1941167 CBMicro_031199 [O-][N+](=O)c1ccc(/C=C/C(=O)NCCSc2ccccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H22 compound treatment 0.333 -0.0081 -0.67 0.337 -0.00558 -0.49 -0.825 -0.9886 1941168 CBMicro_031200 CC(=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H23 positive control 0.088 -0.253 -21.01 0.09 -0.253 -22.38 -30.6856 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 H24 positive control 0.093 -0.248 -20.6 0.094 -0.249 -22.03 -30.1414 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I01 mock treatment 0.34 -0.0011 -0.09 0.343 4.19E-4 0.04 -0.0381 -0.3875 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I02 mock treatment 0.347 0.0059 0.49 0.352 0.00942 0.83 0.9368 0.9678 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I03 compound treatment 0.341 -9.68E-5 -0.01 0.349 0.00642 0.57 0.3966 0.6971 1941169 CBMicro_031201 C/C(=C\C(=O)c1ccccc1)/Nc2cccc(Cl)c2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I04 compound treatment 0.332 -0.0091 -0.76 0.335 -0.00758 -0.67 -1.0091 -0.9983 1134952 CBMicro_031202 CCc1cc(=O)oc2cc(OCc3cccc(C)c3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I05 compound treatment 0.348 0.0069 0.57 0.354 0.0114 1.01 1.1208 0.9637 1192471 CBMicro_031203 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I06 compound treatment 0.369 0.0279 2.32 0.379 0.0364 3.23 3.9202 0.9868 1698042 CBMicro_031204 Clc1cccc(COc2ccc3ccc(=O)oc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I07 compound treatment 0.349 0.0079 0.66 0.344 0.00142 0.13 0.5529 0.8276 1526763 CBMicro_031205 O=C(N1CCCc2ccccc12)c3ccc(cc3)S(=O)(=O)N4CCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I08 compound treatment 0.317 -0.0241 -2.0 0.356 0.0134 1.19 -0.5736 -0.2465 1720032 CBMicro_031206 CC(=C)COc1ccc2c(cc(=O)oc2c1OCC(=C)C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I09 compound treatment 0.318 -0.0231 -1.92 0.332 -0.0106 -0.94 -2.0189 -0.9459 1941170 CBMicro_031207 CCc1cccc(NC(=O)c2cccc(F)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I10 compound treatment 0.34 -0.0011 -0.09 0.344 0.00142 0.13 0.0246 0.1582 1432390 CBMicro_031208 CC(C)OC(=O)COc1cc2oc(=O)cc(C)c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I11 compound treatment 0.339 -0.0021 -0.17 0.345 0.00242 0.21 0.0285 0.1033 1941171 CBMicro_031209 Cc1cc(C)n(n1)C(=O)COc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I12 compound treatment 0.353 0.0119 0.99 0.346 0.00342 0.3 0.913 0.8833 1258805 CBMicro_031210 CC(C)Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I13 compound treatment 0.319 -0.0221 -1.83 0.352 0.00942 0.83 -0.7069 -0.3507 1941172 CBMicro_031211 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I14 compound treatment 0.339 -0.0021 -0.17 0.345 0.00242 0.21 0.0285 0.1033 1776039 CBMicro_031212 Cc1ccc(cc1)C2(CC2C(=O)Nc3cc(ccc3C)[N+](=O)[O-])c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I15 compound treatment 0.343 0.0019 0.16 0.342 -5.81E-4 -0.05 0.0753 0.4534 1214399 CBMicro_031213 Cc1ccc(c(OCC(=O)O)c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I16 compound treatment 0.357 0.0159 1.32 0.349 0.00642 0.57 1.3358 0.9292 1864129 CBMicro_031214 CC(C)c1cccc(C)c1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I17 compound treatment 0.342 9.03E-4 0.07 0.343 4.19E-4 0.04 0.0793 0.9476 1941173 CBMicro_031215 CSc1ccccc1C(=O)O/N=C\2/C(=O)N(C)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I18 compound treatment 0.336 -0.0051 -0.42 0.339 -0.00358 -0.32 -0.5236 -0.9899 1941174 CBMicro_031216 COc1cc(ccc1NC(=O)COc2ccc(Cl)cc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I19 compound treatment 0.368 0.0269 2.23 0.358 0.0154 1.37 2.5456 0.9722 1941175 CBMicro_031217 COc1ccc(OC)c(c1)N(CC(=O)NCc2ccco2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I20 compound treatment 0.335 -0.0061 -0.51 0.336 -0.00658 -0.58 -0.7703 -0.9975 1472056 CBMicro_031218 CC(C)OC(=O)c1c(N)scc1c2cc(C)ccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I21 compound treatment 0.338 -0.0031 -0.26 0.34 -0.00258 -0.23 -0.3435 -0.9983 1941176 CBMicro_031219 FC(F)(F)c1cc(=O)[nH]c(NC(=N)Nc2ccc(cc2)c3ccccc3)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I22 compound treatment 0.344 0.0029 0.24 0.35 0.00742 0.66 0.6354 0.9073 1227143 CBMicro_031220 CCOc1ccc(cc1)N(CC(=O)NCc2ccncc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I23 positive control 0.087 -0.254 -21.09 0.087 -0.256 -22.65 -30.9323 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 I24 positive control 0.094 -0.247 -20.51 0.092 -0.251 -22.21 -30.2081 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J01 mock treatment 0.312 -0.0291 -2.42 0.329 -0.0136 -1.2 -2.5591 -0.9482 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J02 mock treatment 0.344 0.0029 0.24 0.35 0.00742 0.66 0.6354 0.9073 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J03 compound treatment 0.344 0.0029 0.24 0.342 -5.81E-4 -0.05 0.134 0.5439 1941177 CBMicro_031221 COc1cc(OC)c(/C=N/N2CCN(CC2)c3ccccc3)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J04 compound treatment 0.338 -0.0031 -0.26 0.341 -0.00158 -0.14 -0.2808 -0.9592 1941178 CBMicro_031222 [O-][N+](=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J05 compound treatment 0.334 -0.0071 -0.59 0.335 -0.00758 -0.67 -0.8916 -0.9979 1941179 CBMicro_031223 COc1ccc(/C=C/C(=O)NCCSc2ccccn2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J06 compound treatment 0.352 0.0109 0.91 0.357 0.0144 1.28 1.5436 0.9857 1619859 CBMicro_031224 Cc1cccc(OCC(=O)Nc2ccc(C)c(Cl)c2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J07 compound treatment 0.342 9.03E-4 0.07 0.345 0.00242 0.21 0.2046 0.9009 1941180 CBMicro_031225 Cc1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J08 compound treatment 0.34 -0.0011 -0.09 0.347 0.00442 0.39 0.2126 0.5286 1216478 CBMicro_031226 COC(=O)c1ccccc1NC(=O)COc2ccc(cc2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J09 compound treatment 0.335 -0.0061 -0.51 0.336 -0.00658 -0.58 -0.7703 -0.9975 1435743 CBMicro_031227 Brc1ccc2ncnc(NCc3cccnc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J10 compound treatment 0.346 0.0049 0.41 0.353 0.0104 0.92 0.9408 0.9323 1941181 CBMicro_031228 Cc1nc(NC(=S)NCC=C)sc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J11 compound treatment 0.33 -0.0111 -0.92 0.348 0.00542 0.48 -0.3118 -0.3001 1575614 CBMicro_031229 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)Nc3cccnc3)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J12 compound treatment 0.344 0.0029 0.24 0.344 0.00142 0.13 0.2594 0.954 1941182 CBMicro_031230 CCOC(=O)C(=CNCC(=O)O)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J13 compound treatment 0.353 0.0119 0.99 0.353 0.0104 0.92 1.3517 0.9994 1293688 CBMicro_031231 CC(C)c1cccc(C)c1NC(=O)COc2ccc3c(C)cc(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J14 compound treatment 0.344 0.0029 0.24 0.343 4.19E-4 0.04 0.1967 0.8066 1941183 CBMicro_031232 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J15 compound treatment 0.339 -0.0021 -0.17 0.337 -0.00558 -0.49 -0.4728 -0.9018 1941184 CBMicro_031233 CCCc1cc(=O)oc2cc(OC(C)C(=O)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J16 compound treatment 0.342 9.03E-4 0.07 0.347 0.00442 0.39 0.33 0.8275 1941185 CBMicro_031234 Cc1ccccc1CNC(=O)CSc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J17 compound treatment 0.361 0.0199 1.65 0.359 0.0164 1.46 2.1973 0.998 1941186 CBMicro_031235 CCOC(=O)C(=CNc1cc(Cl)c(Cl)cc1Cl)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J18 compound treatment 0.374 0.0329 2.73 0.391 0.0484 4.29 4.9657 0.9762 1941187 CBMicro_031236 COC(=O)CN1C(=O)/C(=C\c2c(F)cccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J19 compound treatment 0.358 0.0169 1.4 0.35 0.00742 0.66 1.4572 0.9403 1737501 CBMicro_031237 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)COc3ccc(cc3)c4ccc(C)cc4)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J20 compound treatment 0.329 -0.0121 -1.0 0.341 -0.00158 -0.14 -0.8092 -0.798 1785433 CBMicro_031238 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J21 compound treatment 0.348 0.0069 0.57 0.352 0.00942 0.83 0.9955 0.9832 1941188 CBMicro_031239 Cc1ccc(NC(=N)Nc2nc(cc(=O)[nH]2)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J22 compound treatment 0.342 9.03E-4 0.07 0.343 4.19E-4 0.04 0.0793 0.9476 1941189 CBMicro_031240 COc1ccc(Cl)cc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J23 positive control 0.087 -0.254 -21.09 0.088 -0.255 -22.56 -30.8696 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 J24 positive control 0.093 -0.248 -20.6 0.095 -0.248 -21.94 -30.0788 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K01 mock treatment 0.337 -0.0041 -0.34 0.341 -0.00158 -0.14 -0.3395 -0.9231 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K02 mock treatment 0.345 0.0039 0.32 0.345 0.00242 0.21 0.3807 0.9799 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K03 compound treatment 0.342 9.03E-4 0.07 0.342 -5.81E-4 -0.05 0.0166 0.1829 1941190 CBMicro_031241 CCOC(=O)C1CCN(CC1)C(=O)/C=C/c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K04 compound treatment 0.387 0.0459 3.81 0.456 0.113 10.05 9.8021 0.9119 1941191 CBMicro_031242 COc1cccc(NC2=C(Cl)C(=O)N(Cc3ccccc3)C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K05 compound treatment 0.337 -0.0041 -0.34 0.336 -0.00658 -0.58 -0.6529 -0.967 1941192 CBMicro_031243 [O-][N+](=O)c1ccc(cc1)/C(=N\OC(=O)c2ccc(Cl)cc2Cl)/c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K06 compound treatment 0.335 -0.0061 -0.51 0.344 0.00142 0.13 -0.269 -0.5157 1941193 CBMicro_031244 CCc1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K07 compound treatment 0.345 0.0039 0.32 0.346 0.00342 0.3 0.4434 0.9994 1454336 CBMicro_031245 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccn5)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K08 compound treatment 0.329 -0.0121 -1.0 0.334 -0.00858 -0.76 -1.2478 -0.9906 1410610 CBMicro_031246 Brc1ccc(COc2ccc3c(c2)oc(=O)c4ccccc43)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K09 compound treatment 0.361 0.0199 1.65 0.359 0.0164 1.46 2.1973 0.998 1121286 CBMicro_031247 COC(=O)c1cc(NC(=O)Cc2ccc(Br)cc2)cc(c1)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K10 compound treatment 0.343 0.0019 0.16 0.339 -0.00358 -0.32 -0.1127 -0.3178 1539695 CBMicro_031248 CN(C)C(=O)COc1ccc2c(C)c(Cc3ccccc3)c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K11 compound treatment 0.373 0.0319 2.65 0.385 0.0424 3.76 4.531 0.9853 1941194 CBMicro_031249 COc1cc(ccc1NC(=O)COc2cccc(Cl)c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K12 compound treatment 0.352 0.0109 0.91 0.348 0.00542 0.48 0.9797 0.956 1941195 CBMicro_031250 COc1c(C2=CC(=O)N(C)C2=O)c3C(=O)c4ccccc4C(=O)c3n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K13 compound treatment 0.339 -0.0021 -0.17 0.335 -0.00758 -0.67 -0.5981 -0.8619 1203449 CBMicro_031251 Cc1ccc(o1)C(=O)Nc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K14 compound treatment 0.345 0.0039 0.32 0.356 0.0134 1.19 1.0701 0.8681 1941196 CBMicro_031252 Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K15 compound treatment 0.356 0.0149 1.24 0.345 0.00242 0.21 1.0265 0.8175 1609315 CBMicro_031253 COc1ccc(NC(=O)COc2ccc(cc2)C(C)C)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K16 compound treatment 0.349 0.0079 0.66 0.37 0.0274 2.43 2.1822 0.867 1941197 CBMicro_031254 FC(F)(F)c1ccc(Cl)c(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K17 compound treatment 0.363 0.0219 1.82 0.365 0.0224 1.99 2.6907 0.999 1941198 CBMicro_031255 [O-][N+](=O)c1ccc(cc1)/C(=N\OC(=O)c2cccc(Br)c2)/c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K18 compound treatment 0.409 0.0679 5.64 0.403 0.0604 5.35 7.7723 0.9997 1941199 CBMicro_031256 Fc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K19 compound treatment 0.331 -0.0101 -0.84 0.337 -0.00558 -0.49 -0.9424 -0.9683 1941200 CBMicro_031257 Cc1cc(C)n2nc(cc2n1)c3cccc(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K20 compound treatment 0.329 -0.0121 -1.0 0.33 -0.0126 -1.11 -1.4985 -0.9986 1941201 CBMicro_031258 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NCCSc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K21 compound treatment 0.124 -0.217 -18.02 0.317 -0.0256 -2.27 -14.3473 -0.7898 1563089 CBMicro_031259 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2ccccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K22 compound treatment 0.34 -0.0011 -0.09 0.341 -0.00158 -0.14 -0.1634 -0.9782 1941202 CBMicro_031260 FC(F)(F)c1cc(=O)[nH]c(NC(=N)Nc2ccc(Oc3ccccc3)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K23 positive control 0.09 -0.251 -20.85 0.09 -0.253 -22.38 -30.5682 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 K24 positive control 0.093 -0.248 -20.6 0.096 -0.247 -21.85 -30.0161 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L01 mock treatment 0.338 -0.0031 -0.26 0.341 -0.00158 -0.14 -0.2808 -0.9592 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L02 mock treatment 0.342 9.03E-4 0.07 0.353 0.0104 0.92 0.706 0.762 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L03 compound treatment 0.343 0.0019 0.16 0.356 0.0134 1.19 0.9527 0.7941 1777547 CBMicro_031261 Cc1ccccc1C2(CC2C(=O)Nc3cccc(c3)[N+](=O)[O-])c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L04 compound treatment 0.344 0.0029 0.24 0.346 0.00342 0.3 0.3847 0.9936 1336827 CBMicro_031262 CCOC(=O)C(C)Oc1ccc2c(=O)c(coc2c1)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L05 compound treatment 0.347 0.0059 0.49 0.348 0.00542 0.48 0.6861 0.9999 1352030 CBMicro_031263 CCc1c(C)[nH]c2cc(nn2c1=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L06 compound treatment 0.33 -0.0111 -0.92 0.331 -0.0116 -1.03 -1.3771 -0.9985 1219675 CBMicro_031264 CCOC(=O)c1cnc2cc(OC)ccc2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L07 compound treatment 0.347 0.0059 0.49 0.344 0.00142 0.13 0.4355 0.8607 1941203 CBMicro_031265 Clc1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L08 compound treatment 0.339 -0.0021 -0.17 0.344 0.00142 0.13 -0.0341 -0.159 1401934 CBMicro_031266 Brc1ccc2ncnc(NCCc3ccccc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L09 compound treatment 0.334 -0.0071 -0.59 0.338 -0.00458 -0.41 -0.7037 -0.9835 1941204 CBMicro_031267 [O-][N+](=O)c1ccccc1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L10 compound treatment 0.337 -0.0041 -0.34 0.336 -0.00658 -0.58 -0.6529 -0.967 1941205 CBMicro_031268 COc1ccc(/C=C(/NC(=O)c2ccccc2Br)\C(=O)NC(Cc3ccccc3)C(=O)O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L11 compound treatment 0.338 -0.0031 -0.26 0.339 -0.00358 -0.32 -0.4062 -0.9945 1941206 CBMicro_031269 CCOC(=O)N1N=C(C)CC1(O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L12 compound treatment 0.365 0.0239 1.98 0.364 0.0214 1.9 2.7454 0.9998 1941207 CBMicro_031270 COC(=O)CCN1C(=O)/C(=C\c2cc(Br)c(O)c(OC)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L13 compound treatment 0.355 0.0139 1.15 0.366 0.0234 2.08 2.2837 0.9616 1941208 CBMicro_031271 COc1ccc(/C=C/C(=O)Nc2c(cccc2C(C)C)C(C)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L14 compound treatment 0.333 -0.0081 -0.67 0.333 -0.00958 -0.85 -1.0757 -0.9933 1594785 CBMicro_031272 Cc1ccccc1CNS(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L15 compound treatment 0.354 0.0129 1.07 0.344 0.00142 0.13 0.8464 0.7847 1863915 CBMicro_031273 Cc1ccc(cc1NC(=O)COc2ccc(Cl)cc2C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L16 compound treatment 0.335 -0.0061 -0.51 0.334 -0.00858 -0.76 -0.8956 -0.9804 1348302 CBMicro_031274 COc1ccc(cc1OC)S(=O)(=O)NCc2ccccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L17 compound treatment 0.404 0.0629 5.22 0.425 0.0824 7.3 8.8574 0.9865 1941209 CBMicro_031275 COc1cccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L18 compound treatment 0.389 0.0479 3.98 0.39 0.0474 4.2 5.7836 0.9996 1941210 CBMicro_031276 CCc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L19 compound treatment 0.34 -0.0011 -0.09 0.337 -0.00558 -0.49 -0.4141 -0.8235 1267378 CBMicro_031277 CC(C)OC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L20 compound treatment 0.331 -0.0101 -0.84 0.332 -0.0106 -0.94 -1.2558 -0.9984 1578248 CBMicro_031278 Cc1ccc(OCC(=O)Nc2ccc(I)cc2C)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L21 compound treatment 0.339 -0.0021 -0.17 0.338 -0.00458 -0.41 -0.4101 -0.9286 1941211 CBMicro_031279 COc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NCc2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L22 compound treatment 0.332 -0.0091 -0.76 0.334 -0.00858 -0.76 -1.0717 -1.0 1332335 CBMicro_031280 Fc1ccccc1COc2ccc3c(c2)oc(=O)c4ccccc43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L23 positive control 0.091 -0.25 -20.76 0.091 -0.252 -22.3 -30.4468 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 L24 positive control 0.092 -0.249 -20.68 0.095 -0.248 -21.94 -30.1375 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M01 mock treatment 0.337 -0.0041 -0.34 0.341 -0.00158 -0.14 -0.3395 -0.9231 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M02 mock treatment 0.336 -0.0051 -0.42 0.34 -0.00258 -0.23 -0.4609 -0.9583 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M03 compound treatment 0.327 -0.0141 -1.17 0.334 -0.00858 -0.76 -1.3652 -0.9782 1785963 CBMicro_031281 CC(Oc1ccccc1)C(=O)Nc2ccc(Cl)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M04 compound treatment 0.342 9.03E-4 0.07 0.349 0.00642 0.57 0.4553 0.7934 1941212 CBMicro_031282 COC(=O)CCN1C(=O)/C(=C\c2ccc(cc2)[N+](=O)[O-])/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M05 compound treatment 0.345 0.0039 0.32 0.342 -5.81E-4 -0.05 0.1927 0.5875 1290265 CBMicro_031283 CCOC(=O)c1c(NC(=O)CCC(=O)OC)sc2CSC(C)(C)Cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M06 compound treatment 0.385 0.0439 3.64 0.394 0.0514 4.56 5.7995 0.9939 1941213 CBMicro_031284 Cc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M07 compound treatment 0.338 -0.0031 -0.26 0.336 -0.00658 -0.58 -0.5942 -0.9323 1941214 CBMicro_031285 OCCCNC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M08 compound treatment 0.334 -0.0071 -0.59 0.336 -0.00658 -0.58 -0.829 -1.0 1354566 CBMicro_031286 Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)c(Cl)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M09 compound treatment 0.343 0.0019 0.16 0.341 -0.00158 -0.14 0.0127 0.06 1323896 CBMicro_031287 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(F)c2)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M10 compound treatment 0.335 -0.0061 -0.51 0.333 -0.00958 -0.85 -0.9583 -0.9694 1396186 CBMicro_031288 CC(C)Oc1cc(C)cc2oc(=O)cc(c3ccccc3)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M11 compound treatment 0.323 -0.0181 -1.5 0.329 -0.0136 -1.2 -1.9134 -0.994 1383784 CBMicro_031289 CCCc1ccc(OCC(=O)Nc2cccc(F)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M12 compound treatment 0.335 -0.0061 -0.51 0.335 -0.00758 -0.67 -0.8329 -0.9903 1025165 CBMicro_031290 O=C(Nc1ccccc1)N2CCN(CC2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M13 compound treatment 0.365 0.0239 1.98 0.365 0.0224 1.99 2.8081 1.0 1546989 CBMicro_031291 Brc1ccc(CC(=O)NC(c2ccccc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M14 compound treatment 0.336 -0.0051 -0.42 0.331 -0.0116 -1.03 -1.0249 -0.9232 1151185 CBMicro_031292 Cc1cc(=O)n2nc(cc2[nH]1)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M15 compound treatment 0.338 -0.0031 -0.26 0.335 -0.00758 -0.67 -0.6568 -0.9131 1530466 CBMicro_031293 CCOC(=O)c1ccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M16 compound treatment 0.362 0.0209 1.74 0.352 0.00942 0.83 1.8174 0.9437 1316684 CBMicro_031294 Cc1cc(C)cc(NC(=O)COc2cccc(C)c2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M17 compound treatment 0.346 0.0049 0.41 0.347 0.00442 0.39 0.5648 0.9998 1941215 CBMicro_031295 COc1cc(cc(OC)c1OC)C(=O)O/N=C(/c2ccncc2)\c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M18 compound treatment 0.34 -0.0011 -0.09 0.34 -0.00258 -0.23 -0.2261 -0.9185 1941216 CBMicro_031296 CN(c1ccc(cc1)C(=O)N)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M19 compound treatment 0.32 -0.0211 -1.75 0.323 -0.0196 -1.74 -2.4655 -1.0 1941217 CBMicro_031297 Fc1ccc(NC(=O)C2C(c3ccccc3)C2(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M20 compound treatment 0.331 -0.0101 -0.84 0.331 -0.0116 -1.03 -1.3184 -0.995 1941218 CBMicro_031298 Cc1ccc(cc1)S(=O)(=O)/N=C/c2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M21 compound treatment 0.349 0.0079 0.66 0.348 0.00542 0.48 0.8035 0.9882 1658030 CBMicro_031299 CC(=O)Nc1cc(nn1Cc2ccc(Cl)cc2)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M22 compound treatment 0.334 -0.0071 -0.59 0.336 -0.00658 -0.58 -0.829 -1.0 1941219 CBMicro_031300 [O-][N+](=O)c1ccccc1S(=O)(=O)NCCSc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M23 positive control 0.088 -0.253 -21.01 0.091 -0.252 -22.3 -30.6229 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 M24 positive control 0.094 -0.247 -20.51 0.095 -0.248 -21.94 -30.0201 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N01 mock treatment 0.345 0.0039 0.32 0.347 0.00442 0.39 0.5061 0.9956 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N02 mock treatment 0.344 0.0029 0.24 0.345 0.00242 0.21 0.322 0.9983 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N03 compound treatment 0.339 -0.0021 -0.17 0.34 -0.00258 -0.23 -0.2848 -0.9909 1421434 CBMicro_031301 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(Cc5ccco5)C2=O)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N04 compound treatment 0.338 -0.0031 -0.26 0.343 4.19E-4 0.04 -0.1555 -0.5987 1941220 CBMicro_031302 Cc1ccc(cc1NC(=O)CCCOc2ccccc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N05 compound treatment 0.342 9.03E-4 0.07 0.343 4.19E-4 0.04 0.0793 0.9476 1941221 CBMicro_031303 COc1ccccc1N2CCN(CC2)/N=C/c3ccccc3C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N06 compound treatment 0.349 0.0079 0.66 0.35 0.00742 0.66 0.9289 1.0 1941222 CBMicro_031304 COc1ccc(/C=C(/NC(=O)c2cc(OC)c(OC)c(OC)c2)\C(=O)NC(C(C)C)C(=O)O)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N07 compound treatment 0.338 -0.0031 -0.26 0.342 -5.81E-4 -0.05 -0.2182 -0.8321 1941223 CBMicro_031305 O=C(CCCOc1ccccc1)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N08 compound treatment 0.34 -0.0011 -0.09 0.358 0.0154 1.37 0.9019 0.6585 1941224 CBMicro_031306 Cc1ccc(cc1)N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4cccc(c4)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N09 compound treatment 0.39 0.0489 4.06 0.381 0.0384 3.4 5.2783 0.9962 1941225 CBMicro_031307 COc1ccc(cc1)N2C(=O)C(=C(Nc3cc(OC)ccc3OC)C2=O)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N10 compound treatment 0.342 9.03E-4 0.07 0.346 0.00342 0.3 0.2673 0.8563 1634934 CBMicro_031308 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2cc(C)cc(C)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N11 compound treatment 0.349 0.0079 0.66 0.346 0.00342 0.3 0.6782 0.9384 1941226 CBMicro_031309 OC(=O)c1ccc(/C=N/N2CCN(CC2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N12 compound treatment 0.343 0.0019 0.16 0.341 -0.00158 -0.14 0.0127 0.06 1646933 CBMicro_031310 COc1ccccc1c2coc3c(CN4CCN(C)CC4)c(O)ccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N13 compound treatment 0.349 0.0079 0.66 0.348 0.00542 0.48 0.8035 0.9882 1941227 CBMicro_031311 COc1cc(/C=C(\NC(=O)c2cc(OC)c(OC)c(OC)c2)/C(=O)NC(C(=O)O)c3ccccc3)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N14 compound treatment 0.357 0.0159 1.32 0.349 0.00642 0.57 1.3358 0.9292 1941228 CBMicro_031312 Cc1ccccc1OCC(=O)NCCSc2ccccn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N15 compound treatment 0.373 0.0319 2.65 0.365 0.0224 1.99 3.2777 0.99 1200743 CBMicro_031313 CC(NC(=O)COc1ccc(cc1)c2ccc(C)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N16 compound treatment 0.343 0.0019 0.16 0.341 -0.00158 -0.14 0.0127 0.06 1941229 CBMicro_031314 Cc1sc2nc(SCC(=O)NCCO)n(c3ccccc3)c(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N17 compound treatment 0.354 0.0129 1.07 0.351 0.00842 0.75 1.2851 0.9844 1941230 CBMicro_031315 CCCCOc1ccc(NC(=O)COc2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N18 compound treatment 0.349 0.0079 0.66 0.349 0.00642 0.57 0.8662 0.9975 1941231 CBMicro_031316 O=C(CCCOc1ccccc1)Nc2ccc(OCc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N19 compound treatment 0.357 0.0159 1.32 0.353 0.0104 0.92 1.5865 0.9847 1254761 CBMicro_031317 COc1ccc(Nc2ncnc3ccc(Br)cc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N20 compound treatment 0.339 -0.0021 -0.17 0.341 -0.00158 -0.14 -0.2221 -0.9942 1193897 CBMicro_031318 CC(C)Nc1ncnc2ccc(Br)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N21 compound treatment 0.357 0.0159 1.32 0.356 0.0134 1.19 1.7745 0.9986 1299093 CBMicro_031319 Cc1ccc(cc1)C2(CC2C(=O)Nc3cccnc3)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N22 compound treatment 0.341 -9.68E-5 -0.01 0.349 0.00642 0.57 0.3966 0.6971 1228441 CBMicro_031320 COc1ccc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N23 positive control 0.089 -0.252 -20.93 0.094 -0.249 -22.03 -30.3762 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 N24 positive control 0.094 -0.247 -20.51 0.097 -0.246 -21.76 -29.8947 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O01 mock treatment 0.342 9.03E-4 0.07 0.344 0.00142 0.13 0.142 0.9694 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O02 mock treatment 0.349 0.0079 0.66 0.344 0.00142 0.13 0.5529 0.8276 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O03 compound treatment 0.337 -0.0041 -0.34 0.339 -0.00358 -0.32 -0.4649 -0.9994 1738214 CBMicro_031321 CC(Oc1ccccc1)C(=O)Nc2cc(Cl)c(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O04 compound treatment 0.332 -0.0091 -0.76 0.34 -0.00258 -0.23 -0.6957 -0.8817 1941232 CBMicro_031322 FC(F)(F)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O05 compound treatment 0.334 -0.0071 -0.59 0.338 -0.00458 -0.41 -0.7037 -0.9835 1562099 CBMicro_031323 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(Cl)c5)c6ccccc36 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O06 compound treatment 0.34 -0.0011 -0.09 0.345 0.00242 0.21 0.0872 0.3745 1213187 CBMicro_031324 Cc1cccc(COc2ccc3c(c2)oc(=O)c4ccccc43)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O07 compound treatment 0.34 -0.0011 -0.09 0.344 0.00142 0.13 0.0246 0.1582 1941233 CBMicro_031325 O=C(CSc1nnc(c2ccc3OCOc3c2)n1c4ccccc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O08 compound treatment 0.333 -0.0081 -0.67 0.334 -0.00858 -0.76 -1.013 -0.9981 1941234 CBMicro_031326 CC(C)Oc1ccc2c(C)cc(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O09 compound treatment 0.352 0.0109 0.91 0.348 0.00542 0.48 0.9797 0.956 1332413 CBMicro_031327 CCc1cccc(C)c1NC(=O)COc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O10 compound treatment 0.333 -0.0081 -0.67 0.334 -0.00858 -0.76 -1.013 -0.9981 1941235 CBMicro_031328 CC(C)Oc1ccc2c(C)c(C)c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O11 compound treatment 0.338 -0.0031 -0.26 0.339 -0.00358 -0.32 -0.4062 -0.9945 1401598 CBMicro_031329 Cc1cc(OCC(=O)Nc2ccccc2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O12 compound treatment 0.344 0.0029 0.24 0.344 0.00142 0.13 0.2594 0.954 1197009 CBMicro_031330 COc1ccc(cc1I)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O13 compound treatment 0.344 0.0029 0.24 0.341 -0.00158 -0.14 0.0714 0.256 1179074 CBMicro_031331 CCc1cccc(C)c1NC(=O)COc2ccc(OC)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O14 compound treatment 0.36 0.0189 1.57 0.355 0.0124 1.1 1.8879 0.9849 1941236 CBMicro_031332 COCCOC(=O)c1ccc(NC(=O)COc2cccc(C)c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O15 compound treatment 0.334 -0.0071 -0.59 0.339 -0.00358 -0.32 -0.641 -0.9579 1137673 CBMicro_031333 Cc1cc(C)n(n1)C(=O)COc2ccc(Oc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O16 compound treatment 0.388 0.0469 3.89 0.38 0.0374 3.32 5.0983 0.9968 1572173 CBMicro_031334 CCN(CC)c1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O17 compound treatment 0.349 0.0079 0.66 0.345 0.00242 0.21 0.6156 0.8918 1941237 CBMicro_031335 Cc1cccc(c1)C(=O)O/N=C(\c2ccncc2)/c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O18 compound treatment 0.331 -0.0101 -0.84 0.334 -0.00858 -0.76 -1.1304 -0.9988 1707402 CBMicro_031336 COc1ccc(Nc2ncnc3[nH]ncc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O19 compound treatment 0.368 0.0269 2.23 0.38 0.0374 3.32 3.9242 0.9815 1781994 CBMicro_031337 [O-][N+](=O)c1cccc(c1)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O20 compound treatment 0.336 -0.0051 -0.42 0.341 -0.00158 -0.14 -0.3982 -0.8935 1740764 CBMicro_031338 COc1ccccc1N2C(=O)CC(Sc3ccccc3C(=O)O)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O21 compound treatment 0.336 -0.0051 -0.42 0.339 -0.00358 -0.32 -0.5236 -0.9899 1941238 CBMicro_031339 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccccc3[N+](=O)[O-])c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O22 compound treatment 0.341 -9.68E-5 -0.01 0.342 -5.81E-4 -0.05 -0.0421 -0.8077 1659261 CBMicro_031340 Cc1ccc(cc1)C2(CC2C(=O)NC(C)(C)C)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O23 positive control 0.088 -0.253 -21.01 0.094 -0.249 -22.03 -30.4349 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 O24 positive control 0.094 -0.247 -20.51 0.098 -0.245 -21.68 -29.8321 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P01 mock treatment 0.34 -0.0011 -0.09 0.338 -0.00458 -0.41 -0.3514 -0.8447 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P02 mock treatment 0.343 0.0019 0.16 0.346 0.00342 0.3 0.326 0.9539 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P03 compound treatment 0.347 0.0059 0.49 0.351 0.00842 0.75 0.8741 0.9792 1941239 CBMicro_031341 O=C1C2C(C3C=CC2C4C3C(=O)N(C4=O)c5ccccc5)C(=O)N1c6ccccc6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P04 compound treatment 0.336 -0.0051 -0.42 0.341 -0.00158 -0.14 -0.3982 -0.8935 1941240 CBMicro_031342 CCc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P05 compound treatment 0.342 9.03E-4 0.07 0.341 -0.00158 -0.14 -0.046 -0.2897 1941241 CBMicro_031343 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccccn6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P06 compound treatment 0.342 9.03E-4 0.07 0.343 4.19E-4 0.04 0.0793 0.9476 1941242 CBMicro_031344 COc1cc(cc(OC)c1OC)C(=O)N/C(=C/c2ccc(F)cc2)/C(=O)NC(C)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P07 compound treatment 0.342 9.03E-4 0.07 0.343 4.19E-4 0.04 0.0793 0.9476 1274470 CBMicro_031345 Cc1cccc(OCC(=O)Nc2ccccc2F)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P08 compound treatment 0.172 -0.169 -14.04 0.19 -0.153 -13.52 -19.488 -0.9998 1941243 CBMicro_031346 COc1cc(/C=N/N2C(=O)CSC2=S)ccc1OCCOc3ccc(C)c(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P09 compound treatment 0.481 0.14 11.61 0.499 0.156 13.86 18.0148 0.9961 1941244 CBMicro_031347 COC(=O)CN1C(=O)/C(=C\c2cccc(O)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P10 compound treatment 0.347 0.0059 0.49 0.345 0.00242 0.21 0.4981 0.9312 1330942 CBMicro_031348 Brc1ccc2ncnc(Nc3ccc4OCCOc4c3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P11 compound treatment 0.352 0.0109 0.91 0.358 0.0154 1.37 1.6063 0.98 1941245 CBMicro_031349 CCOC(=O)C(=CNc1ccccc1O)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P12 compound treatment 0.329 -0.0121 -1.0 0.334 -0.00858 -0.76 -1.2478 -0.9906 1672386 CBMicro_031350 Cc1cccc(OCC(=O)Nc2cc(Cl)ccc2C)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P13 compound treatment 0.345 0.0039 0.32 0.342 -5.81E-4 -0.05 0.1927 0.5875 1176811 CBMicro_031351 COC(=O)c1ccc(C(=O)OC)c(NC(=O)C(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P14 compound treatment 0.347 0.0059 0.49 0.337 -0.00558 -0.49 -0.0032 -0.0046 1941246 CBMicro_031352 CCOC(=O)c1c(C)c(C)sc1NC(=O)/C=C/c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P15 compound treatment 0.342 9.03E-4 0.07 0.344 0.00142 0.13 0.142 0.9694 1349269 CBMicro_031353 COc1cc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P16 compound treatment 0.341 -9.68E-5 -0.01 0.337 -0.00558 -0.49 -0.3554 -0.7185 1234647 CBMicro_031354 Cc1ccc(cc1)N(CC(=O)NCc2ccccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P17 compound treatment 0.341 -9.68E-5 -0.01 0.342 -5.81E-4 -0.05 -0.0421 -0.8077 1941247 CBMicro_031355 CC(Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P18 compound treatment 0.35 0.0089 0.74 0.357 0.0144 1.28 1.4262 0.9661 1941248 CBMicro_031356 COc1ccc(NC(=O)CCCOc2ccccc2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P19 compound treatment 0.331 -0.0101 -0.84 0.338 -0.00458 -0.41 -0.8798 -0.9446 1941249 CBMicro_031357 CC(C)c1cccc(C)c1NC(=O)c2cccc(Br)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P20 compound treatment 0.339 -0.0021 -0.17 0.343 4.19E-4 0.04 -0.0968 -0.5439 1318334 CBMicro_031358 CC(C)OC(=O)COc1ccc2c(C)cc(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P21 compound treatment 0.341 -9.68E-5 -0.01 0.344 0.00142 0.13 0.0833 0.6606 1941250 CBMicro_031359 Cc1cccc(OCC(=O)Nc2cc(ccc2C)[N+](=O)[O-])c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P22 compound treatment 0.382 0.0409 3.4 0.354 0.0114 1.01 3.1167 0.8796 1388111 CBMicro_031360 Cc1cc(Cl)ccc1OCC(=O)Nc2ccc(cc2)S(=O)(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P23 positive control 0.091 -0.25 -20.76 0.096 -0.247 -21.85 -30.1335 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.783 P24 positive control 0.097 -0.244 -20.26 0.107 -0.236 -20.88 -29.092 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A01 mock treatment 0.324 -0.0226 -1.88 0.327 -0.0138 -1.22 -2.1919 -0.9785 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A02 mock treatment 0.335 -0.0116 -0.96 0.337 -0.00381 -0.34 -0.9195 -0.9011 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A03 compound treatment 0.325 -0.0216 -1.79 0.324 -0.0168 -1.49 -2.3212 -0.9957 1941251 CBMicro_031361 COc1cc(ccc1NC(=O)COc2ccc(cc2)c3ccc(C)cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A04 compound treatment 0.339 -0.0076 -0.63 0.331 -0.00981 -0.87 -1.0607 -0.9876 1367175 CBMicro_031362 COc1ccccc1c2coc3c(CN(CC(C)C)CC(C)C)c(O)ccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A05 compound treatment 0.338 -0.0086 -0.71 0.329 -0.0118 -1.05 -1.2447 -0.9826 1720163 CBMicro_031363 CCc1cccc(C)c1NC(=O)c2ccoc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A06 compound treatment 0.322 -0.0246 -2.04 0.318 -0.0228 -2.02 -2.8733 -1.0 1941252 CBMicro_031364 CCOc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)cc(Br)c1OCc3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A07 compound treatment 0.382 0.0354 2.94 0.404 0.0632 5.6 6.0381 0.9547 1941253 CBMicro_031365 Clc1cc(Cl)cc(N/C=C/C(=O)c2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A08 compound treatment 0.328 -0.0186 -1.54 0.322 -0.0188 -1.67 -2.2704 -0.9993 1237053 CBMicro_031366 CC(C)c1cccc(C)c1NC(=O)C2COc3ccccc3O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A09 compound treatment 0.368 0.0214 1.78 0.369 0.0282 2.5 3.023 0.986 1941254 CBMicro_031367 COC(=O)CN1C(=O)/C(=C/c2ccc(OCc3ccc(Cl)cc3)c(OC)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A10 compound treatment 0.327 -0.0196 -1.63 0.31 -0.0308 -2.73 -3.0811 -0.9694 1941255 CBMicro_031368 CCOc1cc(/C=C\2/SC(=S)N(C)C2=O)cc(Br)c1OCc3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A11 compound treatment 0.352 0.0054 0.45 0.343 0.00219 0.19 0.4545 0.9301 1941256 CBMicro_031369 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(cc3)N(CC)CC)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A12 compound treatment 0.373 0.0264 2.19 0.363 0.0222 1.97 2.9405 0.9985 1941257 CBMicro_031370 COc1cc(/C=N/n2cnnc2)cc(Cl)c1OCCOc3ccc(cc3)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A13 compound treatment 0.432 0.0854 7.09 0.419 0.0782 6.93 9.9133 0.9999 1941258 CBMicro_031371 Cc1ccc(cc1)S(=O)(=O)Oc2cccc(/C=C\3/SC(=S)N(CC=C)C3=O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A14 compound treatment 0.346 -6.0E-4 -0.05 0.329 -0.0118 -1.05 -0.7751 -0.7399 1941259 CBMicro_031372 C/C(=C\c1ccccc1)/C=C/2\SC(=NC2=O)N3CCN(CC3)C4=NC(=O)/C(=C\C(=C\c5ccccc5)\C)/S4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A15 compound treatment 0.327 -0.0196 -1.63 0.317 -0.0238 -2.11 -2.6424 -0.9918 1941260 CBMicro_031373 CCOc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A16 compound treatment 0.368 0.0214 1.78 0.368 0.0272 2.41 2.9603 0.9888 1941261 CBMicro_031374 NC(=S)N/N=C/c1ccc(o1)c2ccc(Cl)c(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A17 compound treatment 0.324 -0.0226 -1.88 0.314 -0.0268 -2.38 -3.0065 -0.9932 1237179 CBMicro_031375 CCN1CCN(Cc2c(C)nc3c(Cl)cccc3c2O)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A18 compound treatment 0.36 0.0134 1.11 0.357 0.0162 1.44 1.8014 0.9921 1351088 CBMicro_031376 CCOc1ccc(cc1)c2nc3cc(NC(=O)c4ccc(Br)o4)ccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A19 compound treatment 0.333 -0.0136 -1.13 0.322 -0.0188 -1.67 -1.9769 -0.982 1274803 CBMicro_031377 CCOc1ccccc1NC(=O)COc2ccc(cc2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A20 compound treatment 0.345 -0.0016 -0.13 0.341 1.94E-4 0.02 -0.0818 -0.6107 1501208 CBMicro_031378 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCOCC4)c(=O)n2C1c5ccc(SC)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A21 compound treatment 0.326 -0.0206 -1.71 0.315 -0.0258 -2.29 -2.8265 -0.9897 1308836 CBMicro_031379 Cc1cc(C)c(NC(=O)COc2cccc(Br)c2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A22 compound treatment 0.334 -0.0126 -1.05 0.323 -0.0178 -1.58 -1.8555 -0.9801 1544972 CBMicro_031380 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Br)cn2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A23 positive control 0.085 -0.262 -21.72 0.084 -0.257 -22.76 -31.4496 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 A24 positive control 0.087 -0.26 -21.55 0.088 -0.253 -22.4 -31.0815 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B01 mock treatment 0.341 -0.0056 -0.46 0.331 -0.00981 -0.87 -0.9433 -0.957 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B02 mock treatment 0.352 0.0054 0.45 0.339 -0.00181 -0.16 0.2038 0.4281 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B03 compound treatment 0.336 -0.0106 -0.88 0.332 -0.00881 -0.78 -1.1741 -0.9982 1941262 CBMicro_031381 CCOC(=O)NCc1ccc(Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B04 compound treatment 0.344 -0.0026 -0.22 0.335 -0.00581 -0.51 -0.5165 -0.9256 1670218 CBMicro_031382 CC1=C(C)CC2C(C1)C(=O)N(C2=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B05 compound treatment 0.34 -0.0066 -0.55 0.342 0.00119 0.11 -0.3126 -0.5603 1941263 CBMicro_031383 CCc1cccc(NC(=O)c2cnccn2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B06 compound treatment 0.345 -0.0016 -0.13 0.332 -0.00881 -0.78 -0.6458 -0.8157 1941264 CBMicro_031384 Cc1sc2nc(SCC(=O)NCCCO)n(CC=C)c(=O)c2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B07 compound treatment 0.347 4.0E-4 0.03 0.337 -0.00381 -0.34 -0.2151 -0.6344 1260770 CBMicro_031385 OC(=O)C1C(C2CCC1C2)C(=O)Nc3nc(cs3)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B08 compound treatment 0.346 -6.0E-4 -0.05 0.337 -0.00381 -0.34 -0.2738 -0.8028 1941265 CBMicro_031386 COc1ccc(OC)c(NC(=S)NC(NC(=O)c2ccccc2Br)C(Cl)(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B09 compound treatment 0.328 -0.0186 -1.54 0.313 -0.0278 -2.46 -2.8344 -0.9747 1240392 CBMicro_031387 CCCC1CCc2c(C#N)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B10 compound treatment 0.348 0.0014 0.12 0.334 -0.00681 -0.6 -0.3443 -0.5605 1941266 CBMicro_031388 CCOc1ccc(NC(=S)NC(NC(=O)c2ccc(Br)cc2)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B11 compound treatment 0.458 0.111 9.25 0.442 0.101 8.97 12.8809 0.9999 1941267 CBMicro_031389 CCOc1cc(/C=C/2\SC(=S)N(CC(=O)OC)C2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B12 compound treatment 0.337 -0.0096 -0.8 0.323 -0.0178 -1.58 -1.6794 -0.9499 1941268 CBMicro_031390 COc1ccc(NC2=NCC(C)S2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B13 compound treatment 0.342 -0.0046 -0.38 0.347 0.00619 0.55 0.1181 0.1766 1401061 CBMicro_031391 CC(=O)Oc1cc(C)cc2oc(=O)c3CCCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B14 compound treatment 0.354 0.0074 0.61 0.333 -0.00781 -0.69 -0.0548 -0.0592 1941269 CBMicro_031392 Cc1cccc(OCC(=O)Nc2cccc(c2)C(F)(F)F)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B15 compound treatment 0.342 -0.0046 -0.38 0.332 -0.00881 -0.78 -0.8219 -0.9459 1941270 CBMicro_031393 CC(=O)c1cccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B16 compound treatment 0.354 0.0074 0.61 0.344 0.00319 0.28 0.6345 0.9381 1639055 CBMicro_031394 Cc1cccc(OCC(=O)Nc2ccc(Br)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B17 compound treatment 0.345 -0.0016 -0.13 0.346 0.00519 0.46 0.2315 0.4833 1120372 CBMicro_031395 CC(=O)Oc1ccc2c3CCCCc3c(=O)oc2c1OC(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B18 compound treatment 0.346 -6.0E-4 -0.05 0.334 -0.00681 -0.6 -0.4617 -0.7629 1357344 CBMicro_031396 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccc(C)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B19 compound treatment 0.345 -0.0016 -0.13 0.338 -0.00281 -0.25 -0.2698 -0.9568 1357063 CBMicro_031397 CN(C)C(=O)COc1ccc2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B20 compound treatment 0.334 -0.0126 -1.05 0.319 -0.0218 -1.93 -2.1062 -0.9585 1941271 CBMicro_031398 COC(=O)c1cc(C)sc1NC(=O)C2(C)CC2(Br)Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B21 compound treatment 0.35 0.0034 0.28 0.336 -0.00481 -0.43 -0.1016 -0.1988 1436603 CBMicro_031399 CN(C)C(=O)COc1cc2oc(=O)c3CCCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B22 compound treatment 0.337 -0.0096 -0.8 0.328 -0.0128 -1.13 -1.3661 -0.985 1304691 CBMicro_031400 Cc1cccc(OCC(=O)Nc2ccc(I)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B23 positive control 0.084 -0.263 -21.8 0.085 -0.256 -22.67 -31.4456 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 B24 positive control 0.085 -0.262 -21.72 0.085 -0.256 -22.67 -31.3869 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C01 mock treatment 0.348 0.0014 0.12 0.338 -0.00281 -0.25 -0.0937 -0.3412 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C02 mock treatment 0.356 0.0094 0.78 0.345 0.00419 0.37 0.8146 0.9424 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C03 compound treatment 0.336 -0.0106 -0.88 0.333 -0.00781 -0.69 -1.1114 -0.9929 1941272 CBMicro_031401 COc1ccc(OC)c(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C04 compound treatment 0.447 0.1 8.34 0.445 0.104 9.23 12.4231 0.9987 1285901 CBMicro_031402 CCN(CC)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C05 compound treatment 0.37 0.0234 1.94 0.349 0.00819 0.73 1.8871 0.9099 1197018 CBMicro_031403 CCC1CCc2c(C(=O)N)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C06 compound treatment 0.337 -0.0096 -0.8 0.337 -0.00381 -0.34 -0.8021 -0.9268 1571842 CBMicro_031404 CS(=O)(=O)N(CC(=O)Nc1ccccc1Cl)c2cc(Cl)cc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C07 compound treatment 0.355 0.0084 0.7 0.345 0.00419 0.37 0.7559 0.9566 1941273 CBMicro_031405 Clc1cccc(N/C=C/C(=O)c2ccccc2)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C08 compound treatment 0.376 0.0294 2.44 0.351 0.0102 0.9 2.3647 0.9086 1585671 CBMicro_031406 Cc1c(O)ccc2c3ccccc3c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C09 compound treatment 0.416 0.0694 5.76 0.413 0.0722 6.4 8.598 0.9986 1730213 CBMicro_031407 CCCCN(CC)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C10 compound treatment 0.369 0.0224 1.86 0.357 0.0162 1.44 2.3297 0.9918 1941274 CBMicro_031408 CSc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2Br)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C11 compound treatment 0.405 0.0584 4.85 0.393 0.0522 4.63 6.699 0.9997 1941275 CBMicro_031409 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccccc3Cl)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C12 compound treatment 0.356 0.0094 0.78 0.351 0.0102 0.9 1.1906 0.9973 1334701 CBMicro_031410 CCOc1ccc2ccc(OCC)c(C=c3sc4nc5ccccc5n4c3=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C13 compound treatment 0.433 0.0864 7.17 0.418 0.0772 6.84 9.9093 0.9997 1941276 CBMicro_031411 COc1cc(/C=C\2/SC(=S)NC2=O)cc(Cl)c1OCc3ccccc3F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C14 compound treatment 0.451 0.104 8.67 0.453 0.112 9.94 13.1592 0.9977 1941277 CBMicro_031412 Clc1ccc(NC=C2C(=O)CC(CC2=O)c3ccccc3)c(c1)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C15 compound treatment 0.346 -6.0E-4 -0.05 0.337 -0.00381 -0.34 -0.2738 -0.8028 1691492 CBMicro_031413 Cc1ccc(cc1Cl)N(CC(=O)NCc2ccccc2)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C16 compound treatment 0.468 0.121 10.08 0.474 0.133 11.8 15.4732 0.9969 1941278 CBMicro_031414 Cc1cccc(N2C(=O)/C(=C/c3ccco3)/SC2=S)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C17 compound treatment 0.348 0.0014 0.12 0.342 0.00119 0.11 0.157 0.9989 1714002 CBMicro_031415 Cc1cccc(OCC(=O)Nc2ccc(Cl)cc2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C18 compound treatment 0.328 -0.0186 -1.54 0.325 -0.0158 -1.4 -2.0824 -0.9988 1941279 CBMicro_031416 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2cc(OCC#C)ccc2Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C19 compound treatment 0.337 -0.0096 -0.8 0.33 -0.0108 -0.96 -1.2407 -0.9958 1941280 CBMicro_031417 CCOC(=O)c1c(NC(=O)CCCOc2ccccc2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C20 compound treatment 0.635 0.288 23.94 0.613 0.272 24.12 33.9871 1.0 1941281 CBMicro_031418 CCOC(=O)C1=C(C)N/C(=C\c2cc(C)n(c2C)c3ccccc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C21 compound treatment 0.33 -0.0166 -1.38 0.332 -0.00881 -0.78 -1.5263 -0.9637 1941282 CBMicro_031419 COC(=O)CCN1C(=O)/C(=C\c2c(F)cccc2Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C22 compound treatment 0.337 -0.0096 -0.8 0.321 -0.0198 -1.76 -1.8047 -0.9362 1725750 CBMicro_031420 Cc1cc(OCC(=O)NCc2ccc(F)cc2)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C23 positive control 0.085 -0.262 -21.72 0.086 -0.255 -22.58 -31.3243 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 C24 positive control 0.088 -0.259 -21.47 0.089 -0.252 -22.32 -30.9601 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D01 mock treatment 0.346 -6.0E-4 -0.05 0.341 1.94E-4 0.02 -0.0231 -0.4384 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D02 mock treatment 0.351 0.0044 0.37 0.342 0.00119 0.11 0.3331 0.8759 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D03 compound treatment 0.346 -6.0E-4 -0.05 0.341 1.94E-4 0.02 -0.0231 -0.4384 1941283 CBMicro_031421 OCCCNC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D04 compound treatment 0.347 4.0E-4 0.03 0.345 0.00419 0.37 0.2863 0.7672 1188707 CBMicro_031422 CCN(CC)C(=O)C1(CC2CC3C1)CC(C2)(C3)C(=O)N(CC)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D05 compound treatment 0.36 0.0134 1.11 0.352 0.0112 0.99 1.4881 0.9984 1713545 CBMicro_031423 CC(=O)Oc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(F)cc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D06 compound treatment 0.343 -0.0036 -0.3 0.333 -0.00781 -0.69 -0.7005 -0.9295 1566236 CBMicro_031424 CCC(C(=O)NCc1ccco1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D07 compound treatment 0.338 -0.0086 -0.71 0.333 -0.00781 -0.69 -0.994 -0.9999 1941284 CBMicro_031425 CC(C)/C(=N\NS(=O)(=O)c1ccc(Br)cc1)/c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D08 compound treatment 0.35 0.0034 0.28 0.341 1.94E-4 0.02 0.2117 0.7487 1941285 CBMicro_031426 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2ccccc2Br)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D09 compound treatment 0.349 0.0024 0.2 0.355 0.0142 1.26 1.0303 0.809 1510251 CBMicro_031427 CC1CCc2c(C(=O)N)c(NC(=O)c3cccc(c3)C(=O)O)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D10 compound treatment 0.346 -6.0E-4 -0.05 0.337 -0.00381 -0.34 -0.2738 -0.8028 1941286 CBMicro_031428 COc1ccc(OC)c(NC(=S)NC(NC(=O)c2ccc(Br)cc2)C(Cl)(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D11 compound treatment 0.351 0.0044 0.37 0.344 0.00319 0.28 0.4584 0.992 1941287 CBMicro_031429 Cc1cc(C)c(NC(=O)COc2ccccc2[N+](=O)[O-])c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D12 compound treatment 0.378 0.0314 2.61 0.37 0.0292 2.59 3.6727 1.0 1941288 CBMicro_031430 COc1ccc(cc1)N2C(=O)C(=C(Nc3ccc(C)cc3)C2=O)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D13 compound treatment 0.342 -0.0046 -0.38 0.34 -8.06E-4 -0.07 -0.3206 -0.8251 1941289 CBMicro_031431 Clc1cc(Cl)cc(c1)N2C(=O)C3C(C4C=CC3C5CC54)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D14 compound treatment 0.348 0.0014 0.12 0.346 0.00519 0.46 0.4076 0.8587 1941290 CBMicro_031432 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3cccc(c3)[N+](=O)[O-])cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D15 compound treatment 0.364 0.0174 1.44 0.345 0.00419 0.37 1.2842 0.861 1263563 CBMicro_031433 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3ccccc3Br)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D16 compound treatment 0.465 0.118 9.83 0.473 0.132 11.72 15.2344 0.9962 1941291 CBMicro_031434 CCN(CC)c1ccc(/C=C(/NC(=O)c2ccccc2Br)\C(=O)NCCCC(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D17 compound treatment 0.38 0.0334 2.77 0.344 0.00319 0.28 2.1608 0.7753 1941292 CBMicro_031435 CCc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(C)cc3C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D18 compound treatment 0.375 0.0284 2.36 0.354 0.0132 1.17 2.4939 0.9476 1119798 CBMicro_031436 CCOC(=O)c1sc(NC(=O)COc2cccc(C)c2C)nc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D19 compound treatment 0.34 -0.0066 -0.55 0.333 -0.00781 -0.69 -0.8766 -0.9933 1941293 CBMicro_031437 Cc1c(OCc2ccc(cc2)[N+](=O)[O-])ccc3c4CCCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D20 compound treatment 0.369 0.0224 1.86 0.373 0.0322 2.85 3.3324 0.9785 1941294 CBMicro_031438 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2cccc(Br)c2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D21 compound treatment 0.353 0.0064 0.53 0.337 -0.00381 -0.34 0.1372 0.2179 1175983 CBMicro_031439 CN(C)C(=O)COc1ccc2c3CCCCc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D22 compound treatment 0.352 0.0054 0.45 0.339 -0.00181 -0.16 0.2038 0.4281 1211594 CBMicro_031440 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccccc3C(=O)N)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D23 positive control 0.086 -0.261 -21.63 0.085 -0.256 -22.67 -31.3282 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 D24 positive control 0.09 -0.257 -21.3 0.09 -0.251 -22.23 -30.7801 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E01 mock treatment 0.332 -0.0146 -1.21 0.33 -0.0108 -0.96 -1.5343 -0.9932 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E02 mock treatment 0.352 0.0054 0.45 0.342 0.00119 0.11 0.3918 0.8506 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E03 compound treatment 0.398 0.0514 4.27 0.361 0.0202 1.79 4.2828 0.9256 1941295 CBMicro_031441 COc1cccc(NC2=C(Cl)C(=O)N(C2=O)c3cccc(C)c3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E04 compound treatment 0.332 -0.0146 -1.21 0.329 -0.0118 -1.05 -1.5969 -0.9973 1186420 CBMicro_031442 Cc1ccc2ncnc(NCc3ccco3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E05 compound treatment 0.332 -0.0146 -1.21 0.331 -0.00981 -0.87 -1.4716 -0.9867 1941296 CBMicro_031443 CCC(C)c1ccc(NC(=O)C2CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E06 compound treatment 0.392 0.0454 3.77 0.4 0.0592 5.25 6.3745 0.9868 1941297 CBMicro_031444 CCOc1cc(/C=N/n2cnnc2)ccc1OCCOc3cccc(C)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E07 compound treatment 0.346 -6.0E-4 -0.05 0.341 1.94E-4 0.02 -0.0231 -0.4384 1163134 CBMicro_031445 Brc1ccc2ncnc(Nc3ccccc3)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E08 compound treatment 0.342 -0.0046 -0.38 0.332 -0.00881 -0.78 -0.8219 -0.9459 1941298 CBMicro_031446 CC1CCc2c(C(=O)N)c(NC(=O)CCCOc3ccc(Cl)cc3Cl)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E09 compound treatment 0.335 -0.0116 -0.96 0.332 -0.00881 -0.78 -1.2328 -0.9946 1214763 CBMicro_031447 CCCCN(C)Cc1c(C)nc2c(Cl)cccc2c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E10 compound treatment 0.33 -0.0166 -1.38 0.33 -0.0108 -0.96 -1.6517 -0.9842 1941299 CBMicro_031448 CS(=O)(=O)N(CC(=O)Nc1ccccc1Cl)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E11 compound treatment 0.411 0.0644 5.35 0.397 0.0562 4.98 7.3019 0.9994 1941300 CBMicro_031449 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(cc3)N(CC)CC)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E12 compound treatment 0.495 0.148 12.32 0.492 0.151 13.4 18.1861 0.9991 1941301 CBMicro_031450 Cc1cc(/C=C\2/NC(=S)NC2=O)c(C)n1c3ccc(cc3)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E13 compound treatment 0.341 -0.0056 -0.46 0.339 -0.00181 -0.16 -0.4419 -0.8988 1431474 CBMicro_031451 CCOc1ccc(C=c2sc3nc4ccccc4n3c2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E14 compound treatment 0.373 0.0264 2.19 0.346 0.00519 0.46 1.8752 0.8373 1549197 CBMicro_031452 COc1ccc(cc1NC(=O)c2ccc(Br)o2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E15 compound treatment 0.359 0.0124 1.03 0.339 -0.00181 -0.16 0.6147 0.59 1354578 CBMicro_031453 CCOC(=O)c1ccccc1NC(=O)CN(c2cccc(OC)c2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E16 compound treatment 0.379 0.0324 2.69 0.357 0.0162 1.44 2.9168 0.9567 1941302 CBMicro_031454 COc1cc(ccc1NC(=O)COc2cc(C)ccc2C(C)(C)C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E17 compound treatment 0.393 0.0464 3.85 0.406 0.0652 5.78 6.8092 0.9806 1941303 CBMicro_031455 Cc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E18 compound treatment 0.368 0.0214 1.78 0.363 0.0222 1.97 2.647 0.9987 1941304 CBMicro_031456 COCCOC(=O)c1ccc(NC(=O)c2ccc(cc2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E19 compound treatment 0.338 -0.0086 -0.71 0.333 -0.00781 -0.69 -0.994 -0.9999 1941305 CBMicro_031457 FC(F)(F)c1ccccc1C(=O)Nc2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E20 compound treatment 0.36 0.0134 1.11 0.341 1.94E-4 0.02 0.7988 0.7179 1941306 CBMicro_031458 COc1cccc(c1)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E21 compound treatment 0.351 0.0044 0.37 0.339 -0.00181 -0.16 0.1451 0.3638 1941307 CBMicro_031459 CC(C)c1cccc(C)c1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E22 compound treatment 0.342 -0.0046 -0.38 0.345 0.00419 0.37 -0.0072 -0.0136 1168617 CBMicro_031460 COC(=O)c1c(NC(=O)C(C)C)sc2CCCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E23 positive control 0.086 -0.261 -21.63 0.085 -0.256 -22.67 -31.3282 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 E24 positive control 0.09 -0.257 -21.3 0.093 -0.248 -21.96 -30.5921 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F01 mock treatment 0.343 -0.0036 -0.3 0.335 -0.00581 -0.51 -0.5752 -0.9666 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F02 mock treatment 0.346 -6.0E-4 -0.05 0.339 -0.00181 -0.16 -0.1484 -0.8853 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F03 compound treatment 0.369 0.0224 1.86 0.364 0.0232 2.06 2.7684 0.9988 1210812 CBMicro_031461 CS(=O)(=O)c1ccc2nc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F04 compound treatment 0.35 0.0034 0.28 0.339 -0.00181 -0.16 0.0864 0.2662 1318544 CBMicro_031462 CCOC(=O)COc1cccc2nsnc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F05 compound treatment 0.349 0.0024 0.2 0.348 0.00719 0.64 0.5917 0.8858 1730305 CBMicro_031463 CCOc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F06 compound treatment 0.334 -0.0126 -1.05 0.335 -0.00581 -0.51 -1.1035 -0.9466 1941308 CBMicro_031464 CC(=O)c1ccc(NC(=O)C2CCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F07 compound treatment 0.341 -0.0056 -0.46 0.333 -0.00781 -0.69 -0.8179 -0.9813 1132340 CBMicro_031465 Cc1ccc(cc1)c2nc3ccc(Br)cc3c(C(=O)O)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F08 compound treatment 0.348 0.0014 0.12 0.347 0.00619 0.55 0.4703 0.8383 1941309 CBMicro_031466 CCOC(=O)c1ccc(NC(=S)NC(NC(=O)c2ccccc2Cl)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F09 compound treatment 0.334 -0.0126 -1.05 0.321 -0.0198 -1.76 -1.9808 -0.9694 1941310 CBMicro_031467 COC(=O)c1c(N)sc(C)c1c2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F10 compound treatment 0.346 -6.0E-4 -0.05 0.354 0.0132 1.17 0.7916 0.6764 1941311 CBMicro_031468 Cc1ccc(cc1)C(=O)NC(NC(=S)Nc2ccccc2Br)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F11 compound treatment 0.358 0.0114 0.95 0.345 0.00419 0.37 0.932 0.9166 1941312 CBMicro_031469 CCN(CC)c1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F12 compound treatment 0.338 -0.0086 -0.71 0.351 0.0102 0.9 0.1339 0.1163 1941313 CBMicro_031470 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCN6CCOCC6 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F13 compound treatment 0.35 0.0034 0.28 0.341 1.94E-4 0.02 0.2117 0.7487 1941314 CBMicro_031471 Cc1ccc(F)c(N/C=C/C(=O)c2ccc(Br)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F14 compound treatment 0.342 -0.0046 -0.38 0.334 -0.00681 -0.6 -0.6966 -0.9757 1941315 CBMicro_031472 CC(=O)c1cccc(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F15 compound treatment 0.345 -0.0016 -0.13 0.343 0.00219 0.19 0.0435 0.1849 1532450 CBMicro_031473 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(OC)c3OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F16 compound treatment 0.354 0.0074 0.61 0.351 0.0102 0.9 1.0732 0.9823 1941316 CBMicro_031474 Cc1c(Cl)cccc1NC(=O)CCCOc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F17 compound treatment 0.358 0.0114 0.95 0.353 0.0122 1.08 1.4333 0.9978 1522341 CBMicro_031475 CC(=C)COc1ccc2c3CCCCc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F18 compound treatment 0.385 0.0384 3.19 0.372 0.0312 2.76 4.209 0.9975 1941317 CBMicro_031476 COc1ccc(NC(=O)COc2cccc(C)c2C)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F19 compound treatment 0.38 0.0334 2.77 0.384 0.0432 3.83 4.6674 0.9875 1473118 CBMicro_031477 Cc1cc(OCc2ccc(F)cc2)c3c4CCCCc4c(=O)oc3c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F20 compound treatment 0.365 0.0184 1.53 0.367 0.0262 2.32 2.7216 0.9794 1941318 CBMicro_031478 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2ccc(F)cc2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F21 compound treatment 0.348 0.0014 0.12 0.338 -0.00281 -0.25 -0.0937 -0.3412 1941319 CBMicro_031479 CC(Oc1cc(C)cc2oc(=O)c3CCCCc3c12)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F22 compound treatment 0.34 -0.0066 -0.55 0.328 -0.0128 -1.13 -1.19 -0.9442 1941320 CBMicro_031480 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccccc3C(F)(F)F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F23 positive control 0.087 -0.26 -21.55 0.088 -0.253 -22.4 -31.0815 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 F24 positive control 0.09 -0.257 -21.3 0.091 -0.25 -22.14 -30.7174 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G01 mock treatment 0.336 -0.0106 -0.88 0.335 -0.00581 -0.51 -0.9861 -0.9673 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G02 mock treatment 0.342 -0.0046 -0.38 0.336 -0.00481 -0.43 -0.5712 -0.9985 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G03 compound treatment 0.339 -0.0076 -0.63 0.333 -0.00781 -0.69 -0.9353 -0.9989 1287129 CBMicro_031481 CCc1cc(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G04 compound treatment 0.336 -0.0106 -0.88 0.336 -0.00481 -0.43 -0.9235 -0.9445 1247201 CBMicro_031482 CCc1ccc2ncc(C(=O)O)c(O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G05 compound treatment 0.453 0.106 8.83 0.467 0.126 11.18 14.154 0.9932 1941321 CBMicro_031483 [O-][N+](=O)c1cc(N/C=C/C(=O)c2ccccc2)ccc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G06 compound treatment 0.342 -0.0046 -0.38 0.34 -8.06E-4 -0.07 -0.3206 -0.8251 1941322 CBMicro_031484 Cc1cccc(OCCOc2ccccc2/C=N/n3cnnc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G07 compound treatment 0.335 -0.0116 -0.96 0.35 0.00919 0.81 -0.1048 -0.0831 1941323 CBMicro_031485 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2ccc(Cl)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G08 compound treatment 0.351 0.0044 0.37 0.347 0.00619 0.55 0.6464 0.9804 1310163 CBMicro_031486 COC(=O)c1ccc(C(=O)OC)c(NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G09 compound treatment 0.342 -0.0046 -0.38 0.333 -0.00781 -0.69 -0.7592 -0.9608 1283505 CBMicro_031487 CCOC(=O)c1c(NC(=O)c2cncc(Br)c2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G10 compound treatment 0.346 -6.0E-4 -0.05 0.339 -0.00181 -0.16 -0.1484 -0.8853 1551379 CBMicro_031488 COc1ccc(N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)C)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G11 compound treatment 0.396 0.0494 4.1 0.385 0.0442 3.92 5.6693 0.9997 1941324 CBMicro_031489 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccccc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G12 compound treatment 0.378 0.0314 2.61 0.38 0.0392 3.47 4.2994 0.99 1941325 CBMicro_031490 COc1cc(/C=N/n2cnnc2)ccc1OCCSc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G13 compound treatment 0.573 0.226 18.8 0.579 0.238 21.11 28.2168 0.9983 1941326 CBMicro_031491 [O-][N+](=O)c1ccccc1S(=O)(=O)Oc2ccc(/C=C\3/SC(=S)N(CC=C)C3=O)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G14 compound treatment 0.335 -0.0116 -0.96 0.329 -0.0118 -1.05 -1.4208 -0.9991 1179973 CBMicro_031492 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G15 compound treatment 0.361 0.0144 1.2 0.377 0.0362 3.21 3.1134 0.9095 1941327 CBMicro_031493 Cc1cccc(OCCOc2ccc(/C=N/n3cnnc3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G16 compound treatment 0.383 0.0364 3.02 0.385 0.0442 3.92 4.9062 0.9918 1941328 CBMicro_031494 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Cl)cc3)C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G17 compound treatment 0.385 0.0384 3.19 0.383 0.0422 3.74 4.8983 0.9968 1941329 CBMicro_031495 COc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G18 compound treatment 0.336 -0.0106 -0.88 0.337 -0.00381 -0.34 -0.8608 -0.9134 1941330 CBMicro_031496 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3ccc(C)cc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G19 compound treatment 0.358 0.0114 0.95 0.361 0.0202 1.79 1.9346 0.9556 1507249 CBMicro_031497 COc1cccc(c1)N(CC(=O)Nc2ccc3ccccc3c2)S(=O)(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G20 compound treatment 0.351 0.0044 0.37 0.358 0.0172 1.52 1.3357 0.8525 1941331 CBMicro_031498 [O-][N+](=O)c1ccccc1S(=O)(=O)N(CC(=O)Nc2ccc(Br)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G21 compound treatment 0.781 0.434 36.06 0.78 0.439 38.92 53.0228 0.9993 1941332 CBMicro_031499 CCc1ccc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G22 compound treatment 0.321 -0.0256 -2.13 0.322 -0.0188 -1.67 -2.6813 -0.9928 1941333 CBMicro_031500 CCOc1ccc(Br)cc1/C=N\NC(=O)c2cc(C)n[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G23 positive control 0.081 -0.266 -22.05 0.086 -0.255 -22.58 -31.5591 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 G24 positive control 0.092 -0.255 -21.14 0.093 -0.248 -21.96 -30.4747 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H01 mock treatment 0.338 -0.0086 -0.71 0.334 -0.00681 -0.6 -0.9314 -0.9965 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H02 mock treatment 0.344 -0.0026 -0.22 0.339 -0.00181 -0.16 -0.2658 -0.9892 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H03 compound treatment 0.33 -0.0166 -1.38 0.328 -0.0128 -1.13 -1.777 -0.9954 1276784 CBMicro_031501 COc1ccc(Cl)cc1C(=O)NCC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H04 compound treatment 0.327 -0.0196 -1.63 0.32 -0.0208 -1.84 -2.4544 -0.9981 1941334 CBMicro_031502 CC(C)(C)C(=O)/C=C/c1ccc(cc1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H05 compound treatment 0.342 -0.0046 -0.38 0.344 0.00319 0.28 -0.0699 -0.1471 1134909 CBMicro_031503 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCC(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H06 compound treatment 0.332 -0.0146 -1.21 0.331 -0.00981 -0.87 -1.4716 -0.9867 1141631 CBMicro_031504 COc1ccc2C(Nc3ccccc3Br)OC(=O)c2c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H07 compound treatment 0.354 0.0074 0.61 0.342 0.00119 0.11 0.5092 0.8168 1941335 CBMicro_031505 C/C(=N\NC(=O)C1(C)CC1(Br)Br)/c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H08 compound treatment 0.328 -0.0186 -1.54 0.326 -0.0148 -1.31 -2.0197 -0.9967 1941336 CBMicro_031506 CCOc1ccc(NC(=S)NC(NC(=O)c2ccccc2Br)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H09 compound treatment 0.353 0.0064 0.53 0.347 0.00619 0.55 0.7638 0.9999 1382930 CBMicro_031507 CC(C)OC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H10 compound treatment 0.373 0.0264 2.19 0.362 0.0212 1.88 2.8779 0.997 1941337 CBMicro_031508 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2ccc(Cl)cc2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H11 compound treatment 0.324 -0.0226 -1.88 0.324 -0.0168 -1.49 -2.3799 -0.9935 1732094 CBMicro_031509 CCOC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2C)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H12 compound treatment 0.349 0.0024 0.2 0.331 -0.00981 -0.87 -0.4736 -0.5312 1322623 CBMicro_031510 COc1ccc(NC(=O)COc2cccc(C)c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H13 compound treatment 0.371 0.0244 2.03 0.372 0.0312 2.76 3.3871 0.9883 1666118 CBMicro_031511 Clc1ccc(NC(=O)C2C3CCCCC=CC23)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H14 compound treatment 0.372 0.0254 2.11 0.368 0.0272 2.41 3.1952 0.9978 1941338 CBMicro_031512 Cc1cc(Cl)ccc1OCC(=O)Nc2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H15 compound treatment 0.33 -0.0166 -1.38 0.329 -0.0118 -1.05 -1.7143 -0.9908 1154571 CBMicro_031513 CNC(=O)CC1Sc2ccccc2NC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H16 compound treatment 0.327 -0.0196 -1.63 0.329 -0.0118 -1.05 -1.8904 -0.9772 1662574 CBMicro_031514 Brc1cncc(c1)C(=O)NCCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H17 compound treatment 0.408 0.0614 5.1 0.399 0.0582 5.16 7.2511 1.0 1378934 CBMicro_031515 Cc1c(OCc2ccccc2F)ccc3c4CCCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H18 compound treatment 0.384 0.0374 3.1 0.371 0.0302 2.68 4.0876 0.9973 1388029 CBMicro_031516 COC(=O)c1cccc(NC(=O)COc2ccc(cc2)c3ccc(C)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H19 compound treatment 0.352 0.0054 0.45 0.355 0.0142 1.26 1.2064 0.9035 1941339 CBMicro_031517 CC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H20 compound treatment 0.369 0.0224 1.86 0.385 0.0442 3.92 4.0843 0.9421 1941340 CBMicro_031518 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2cccc3ccccc23)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H21 compound treatment 0.334 -0.0126 -1.05 0.334 -0.00681 -0.6 -1.1662 -0.9658 1545165 CBMicro_031519 COc1cc(C)cc2oc(=O)c3CCCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H22 compound treatment 0.329 -0.0176 -1.46 0.334 -0.00681 -0.6 -1.4597 -0.9234 1723368 CBMicro_031520 CCCOC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H23 positive control 0.086 -0.261 -21.63 0.086 -0.255 -22.58 -31.2655 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 H24 positive control 0.092 -0.255 -21.14 0.095 -0.246 -21.78 -30.3493 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I01 mock treatment 0.351 0.0044 0.37 0.348 0.00719 0.64 0.7091 0.9651 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I02 mock treatment 0.352 0.0054 0.45 0.345 0.00419 0.37 0.5798 0.9957 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I03 compound treatment 0.375 0.0284 2.36 0.367 0.0262 2.32 3.3086 1.0 1706341 CBMicro_031521 CCc1cc(=O)oc2cc(OCc3ccc(C)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I04 compound treatment 0.34 -0.0066 -0.55 0.333 -0.00781 -0.69 -0.8766 -0.9933 1214035 CBMicro_031522 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I05 compound treatment 0.59 0.243 20.21 0.578 0.237 21.02 29.1521 0.9998 1941341 CBMicro_031523 CC(=O)Nc1ccc(N/C=C/C(=O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I06 compound treatment 0.334 -0.0126 -1.05 0.33 -0.0108 -0.96 -1.4168 -0.999 1320962 CBMicro_031524 COc1cccc(NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I07 compound treatment 0.368 0.0214 1.78 0.365 0.0242 2.14 2.7723 0.9956 1941342 CBMicro_031525 Cc1ccc(C)c(NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I08 compound treatment 0.343 -0.0036 -0.3 0.324 -0.0168 -1.49 -1.2645 -0.8324 1306966 CBMicro_031526 Cc1cc(=O)oc2cc(OCC(=O)OC(C)(C)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I09 compound treatment 0.39 0.0434 3.6 0.404 0.0632 5.6 6.5078 0.9773 1941343 CBMicro_031527 ClC1=C(N2CCN(CC2)c3ccccc3)C(=O)N(C1=O)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I10 compound treatment 0.366 0.0194 1.61 0.349 0.00819 0.73 1.6523 0.9352 1727228 CBMicro_031528 COC(=O)c1ccccc1NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(SC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I11 compound treatment 0.406 0.0594 4.93 0.396 0.0552 4.89 6.9457 1.0 1941344 CBMicro_031529 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3cccc(c3)[N+](=O)[O-])/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I12 compound treatment 0.364 0.0174 1.44 0.376 0.0352 3.12 3.2268 0.9388 1941345 CBMicro_031530 COc1cc(/C=N/n2cnnc2)cc(I)c1OCCOc3ccccc3CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I13 compound treatment 0.362 0.0154 1.28 0.369 0.0282 2.5 2.6708 0.9516 1941346 CBMicro_031531 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(cc(Br)c3O)[N+](=O)[O-])c(=O)n2C1c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I14 compound treatment 0.375 0.0284 2.36 0.381 0.0402 3.56 4.1859 0.9799 1533969 CBMicro_031532 CCOc1cccc(c1)C(=O)Nc2cc(ccc2C)c3nc4cc(C)cc(C)c4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I15 compound treatment 0.381 0.0344 2.86 0.359 0.0182 1.61 3.1595 0.9634 1941347 CBMicro_031533 CCN1C(=O)/C(=C\c2cccc(OCc3ccc(Cl)cc3Cl)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I16 compound treatment 0.396 0.0494 4.1 0.394 0.0532 4.71 6.2333 0.9976 1941348 CBMicro_031534 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(c3)[N+](=O)[O-])C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I17 compound treatment 0.364 0.0174 1.44 0.361 0.0202 1.79 2.2869 0.9944 1740199 CBMicro_031535 Cc1ccc(cc1)c2ccc(OCC(=O)NCCc3ccccc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I18 compound treatment 0.354 0.0074 0.61 0.368 0.0272 2.41 2.1385 0.8599 1398080 CBMicro_031536 CCCOC(=O)c1c(N)sc2CCCCCc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I19 compound treatment 0.368 0.0214 1.78 0.366 0.0252 2.23 2.835 0.9936 1941349 CBMicro_031537 CCOc1cc(/C=C\2/SC(=S)N(CC)C2=O)cc(Br)c1OCCOc3cccc(OC)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I20 compound treatment 0.343 -0.0036 -0.3 0.342 0.00119 0.11 -0.1365 -0.4307 1941350 CBMicro_031538 CCOc1cc(/C=C\2/SC(=S)N(C)C2=O)cc(Br)c1OCc3ccccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I21 compound treatment 0.35 0.0034 0.28 0.339 -0.00181 -0.16 0.0864 0.2662 1941351 CBMicro_031539 CCCOc1ccc2c(C)cc(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I22 compound treatment 0.364 0.0174 1.44 0.347 0.00619 0.55 1.4096 0.9122 1324607 CBMicro_031540 O=C(Cc1ccccc1)Nc2cccc(c2)c3nc4ccccc4c(=O)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I23 positive control 0.088 -0.259 -21.47 0.087 -0.254 -22.49 -31.0855 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 I24 positive control 0.095 -0.252 -20.89 0.094 -0.247 -21.87 -30.2359 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J01 mock treatment 0.324 -0.0226 -1.88 0.321 -0.0198 -1.76 -2.5679 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J02 mock treatment 0.35 0.0034 0.28 0.349 0.00819 0.73 0.713 0.9153 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J03 compound treatment 0.334 -0.0126 -1.05 0.322 -0.0188 -1.67 -1.9182 -0.9748 1168806 CBMicro_031541 CCCC(=O)N1CCN(Cc2ccccc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J04 compound treatment 0.35 0.0034 0.28 0.344 0.00319 0.28 0.3997 1.0 1941352 CBMicro_031542 COc1cc(/C=N/n2cnnc2)ccc1OC(=O)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J05 compound treatment 0.179 -0.168 -13.91 0.162 -0.179 -15.85 -21.0436 -0.9979 1941353 CBMicro_031543 NC(=O)/C=C/C(=O)Nc1ccc2OCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J06 compound treatment 0.339 -0.0076 -0.63 0.322 -0.0188 -1.67 -1.6247 -0.9117 1941354 CBMicro_031544 CC1=C(C(NC(=S)N1)c2ccccc2Br)C(=O)Nc3cc(Cl)ccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J07 compound treatment 0.347 4.0E-4 0.03 0.342 0.00119 0.11 0.0983 0.8864 1170511 CBMicro_031545 COc1ccc(NC(=O)C2C(C3CCC2C3=C(C)C)C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J08 compound treatment 0.343 -0.0036 -0.3 0.339 -0.00181 -0.16 -0.3245 -0.9572 1941355 CBMicro_031546 CCCCOC(=O)c1ccc(NC(=S)NC(NC(=O)Cc2ccccc2)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J09 compound treatment 0.351 0.0044 0.37 0.34 -8.06E-4 -0.07 0.2078 0.5582 1299857 CBMicro_031547 CCOc1ccc(NC(=O)C2C(C3CCC2C3=C(C)C)C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J10 compound treatment 0.36 0.0134 1.11 0.357 0.0162 1.44 1.8014 0.9921 1941356 CBMicro_031548 CCOC(=O)c1ccc(NC(=S)NC(NC(=O)c2ccc(Br)cc2)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J11 compound treatment 0.334 -0.0126 -1.05 0.331 -0.00981 -0.87 -1.3542 -0.9958 1286785 CBMicro_031549 O=C(NCc1ccco1)C2C3C2C4CCC3C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J12 compound treatment 0.358 0.0114 0.95 0.342 0.00119 0.11 0.744 0.7813 1941357 CBMicro_031550 [O-][N+](=O)c1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J13 compound treatment 0.341 -0.0056 -0.46 0.337 -0.00381 -0.34 -0.5673 -0.9876 1535579 CBMicro_031551 COC(=O)c1ccc(NC(=O)C2C(C3C=CC2C4CC43)C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J14 compound treatment 0.341 -0.0056 -0.46 0.336 -0.00481 -0.43 -0.6299 -0.999 1941358 CBMicro_031552 CCCCOc1ccc(cc1)c2n[nH]c(N)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J15 compound treatment 0.331 -0.0156 -1.3 0.34 -8.06E-4 -0.07 -0.9663 -0.745 1941359 CBMicro_031553 O=C(NCCCc1ccccc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J16 compound treatment 0.413 0.0664 5.51 0.404 0.0632 5.6 7.8579 1.0 1262493 CBMicro_031554 CN(Cc1ccccc1)Cc2c(O)ccc3c(cc(=O)oc23)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J17 compound treatment 0.352 0.0054 0.45 0.355 0.0142 1.26 1.2064 0.9035 1392276 CBMicro_031555 CCc1cc2c3CCCCc3c(=O)oc2cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J18 compound treatment 0.375 0.0284 2.36 0.358 0.0172 1.52 2.7446 0.9777 1305795 CBMicro_031556 CC(C)c1cccc(C)c1NC(=O)Nc2cccc(Cl)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J19 compound treatment 0.376 0.0294 2.44 0.396 0.0552 4.89 5.1846 0.9484 1535616 CBMicro_031557 CCOC(=O)c1ccc(Nc2ncnc3ccc(C)cc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J20 compound treatment 0.332 -0.0146 -1.21 0.331 -0.00981 -0.87 -1.4716 -0.9867 1403257 CBMicro_031558 COC(=O)c1ccc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J21 compound treatment 0.369 0.0224 1.86 0.364 0.0232 2.06 2.7684 0.9988 1561193 CBMicro_031559 Cc1c(OCc2ccccc2)ccc3c4CCCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J22 compound treatment 0.334 -0.0126 -1.05 0.341 1.94E-4 0.02 -0.7275 -0.6954 1863907 CBMicro_031560 CC(C)c1cccc(C(C)C)c1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J23 positive control 0.089 -0.258 -21.39 0.088 -0.253 -22.4 -30.9641 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 J24 positive control 0.099 -0.248 -20.56 0.092 -0.249 -22.05 -30.1264 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K01 mock treatment 0.341 -0.0056 -0.46 0.341 1.94E-4 0.02 -0.3166 -0.6806 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K02 mock treatment 0.349 0.0024 0.2 0.35 0.00919 0.81 0.717 0.8548 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K03 compound treatment 0.336 -0.0106 -0.88 0.331 -0.00981 -0.87 -1.2368 -1.0 1523053 CBMicro_031561 Clc1ccc(cc1)C(=O)COc2cc3oc(=O)c4CCCc4c3cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K04 compound treatment 0.353 0.0064 0.53 0.34 -8.06E-4 -0.07 0.3252 0.6065 1941360 CBMicro_031562 COC(=O)CN1C(=O)/C(=C\c2ccc(F)cc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K05 compound treatment 0.407 0.0604 5.01 0.404 0.0632 5.6 7.5057 0.9985 1941361 CBMicro_031563 Fc1ccccc1N/C=C/C(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K06 compound treatment 0.345 -0.0016 -0.13 0.333 -0.00781 -0.69 -0.5831 -0.8278 1941362 CBMicro_031564 CS(=O)(=O)N(CC(=O)NCC=C)c1cccc(c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K07 compound treatment 0.376 0.0294 2.44 0.35 0.00919 0.81 2.302 0.8946 1941363 CBMicro_031565 Cc1cc(Cl)ccc1OCC(=O)Nc2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K08 compound treatment 0.354 0.0074 0.61 0.341 1.94E-4 0.02 0.4465 0.7266 1312641 CBMicro_031566 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccc(F)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K09 compound treatment 0.363 0.0164 1.36 0.346 0.00519 0.46 1.2882 0.8963 1236043 CBMicro_031567 COc1ccccc1c2coc3cc(OC(=O)c4ccc(Cl)cc4)ccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K10 compound treatment 0.317 -0.0296 -2.46 0.308 -0.0328 -2.91 -3.7934 -0.9965 1432872 CBMicro_031568 CCN(CC)c1ccc(NC(=O)S(=O)(=O)c2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K11 compound treatment 0.399 0.0524 4.35 0.389 0.0482 4.27 6.0961 1.0 1693919 CBMicro_031569 COc1ccccc1C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K12 compound treatment 0.404 0.0574 4.77 0.381 0.0402 3.56 5.8883 0.9897 1941364 CBMicro_031570 CCOc1cc(/C=N/n2cnnc2)ccc1OCCOc3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K13 compound treatment 0.244 -0.103 -8.52 0.267 -0.0738 -6.54 -10.648 -0.9915 1941365 CBMicro_031571 Fc1ccc(cc1Cl)c2ccc(/C=C\3/SC(=S)N(CC=C)C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K14 compound treatment 0.341 -0.0056 -0.46 0.332 -0.00881 -0.78 -0.8806 -0.9694 1778409 CBMicro_031572 [O-][N+](=O)c1cccc(c1)C(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)c5nc6ccccc6o5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K15 compound treatment 0.355 0.0084 0.7 0.359 0.0182 1.61 1.6332 0.9297 1941366 CBMicro_031573 CCc1cc(C)cc(OCCOc2ccc(/C=N/n3cnnc3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K16 compound treatment 0.367 0.0204 1.69 0.35 0.00919 0.81 1.7737 0.9438 1142036 CBMicro_031574 COc1ccc(NC(=O)COc2ccccc2C(C)C)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K17 compound treatment 0.351 0.0044 0.37 0.354 0.0132 1.17 1.0851 0.8858 1941367 CBMicro_031575 COc1cc(cc(OC)c1OC)C(=O)N/C(=C/c2ccc(Br)cc2)/C(=O)NC(C)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K18 compound treatment 0.542 0.195 16.22 0.545 0.204 18.1 24.2664 0.9985 1941368 CBMicro_031576 OS(=O)(=O)c1cccc2c(NN=C(C#N)C#N)cccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K19 compound treatment 0.352 0.0054 0.45 0.343 0.00219 0.19 0.4545 0.9301 1941369 CBMicro_031577 Cc1ccc(OCCOc2ccc(Br)cc2/C=N/n3cnnc3)cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K20 compound treatment 0.396 0.0494 4.1 0.371 0.0302 2.68 4.792 0.9786 1941370 CBMicro_031578 CCc1cc(C)cc(OCCOc2ccccc2/C=N/n3cnnc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K21 compound treatment 0.316 -0.0306 -2.54 0.312 -0.0288 -2.55 -3.6015 -1.0 1563578 CBMicro_031579 Cc1c(OCC(=O)c2ccccc2)ccc3c4CCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K22 compound treatment 0.342 -0.0046 -0.38 0.334 -0.00681 -0.6 -0.6966 -0.9757 1941371 CBMicro_031580 Brc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3cccc4ccccc34)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K23 positive control 0.094 -0.253 -20.97 0.086 -0.255 -22.58 -30.7959 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 K24 positive control 0.102 -0.245 -20.31 0.094 -0.247 -21.87 -29.825 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L01 mock treatment 0.344 -0.0026 -0.22 0.341 1.94E-4 0.02 -0.1405 -0.6489 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L02 mock treatment 0.346 -6.0E-4 -0.05 0.343 0.00219 0.19 0.1022 0.5095 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L03 compound treatment 0.337 -0.0096 -0.8 0.329 -0.0118 -1.05 -1.3034 -0.991 1941372 CBMicro_031581 CCOc1ccc(cc1)S(=O)(=O)N/N=C/c2c(C)[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L04 compound treatment 0.338 -0.0086 -0.71 0.329 -0.0118 -1.05 -1.2447 -0.9826 1941373 CBMicro_031582 CC(C)(C)c1cnnn1c2ccc(C=O)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L05 compound treatment 0.343 -0.0036 -0.3 0.347 0.00619 0.55 0.1768 0.2829 1941374 CBMicro_031583 CCc1c(nc2ccc(Br)cc2c1C(=O)O)c3ccc(Cl)s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L06 compound treatment 0.354 0.0074 0.61 0.35 0.00919 0.81 1.0105 0.9903 1941375 CBMicro_031584 [O-][N+](=O)c1cccc(c1)C(=O)NC(NC(=S)Nc2ccc(I)cc2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L07 compound treatment 0.334 -0.0126 -1.05 0.336 -0.00481 -0.43 -1.0409 -0.9216 1211165 CBMicro_031585 CC(C)(C)C1CCc2nc3ccccc3c(C(=O)O)c2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L08 compound treatment 0.335 -0.0116 -0.96 0.34 -8.06E-4 -0.07 -0.7315 -0.7575 1941376 CBMicro_031586 [O-][N+](=O)c1cccc(c1)C(=O)NC(NC(=S)Nc2ccccc2I)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L09 compound treatment 0.343 -0.0036 -0.3 0.338 -0.00281 -0.25 -0.3872 -0.9958 1448056 CBMicro_031587 OC(=O)C1C(C2CCC1O2)C(=O)NCCC3=CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L10 compound treatment 0.351 0.0044 0.37 0.345 0.00419 0.37 0.5211 1.0 1941377 CBMicro_031588 COc1ccc(OC)c(NC(=S)NC(NC(=O)c2cccc(I)c2)C(Cl)(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L11 compound treatment 0.359 0.0124 1.03 0.373 0.0322 2.85 2.7453 0.9051 1941378 CBMicro_031589 COC(=O)c1ccccc1N/C=C/C(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L12 compound treatment 0.352 0.0054 0.45 0.342 0.00119 0.11 0.3918 0.8506 1268949 CBMicro_031590 CC(=O)Oc1ccc2c3CCCCc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L13 compound treatment 0.352 0.0054 0.45 0.341 1.94E-4 0.02 0.3291 0.7336 1433241 CBMicro_031591 COc1cccc(NC(=O)C2CC2(c3cccc(OC)c3)c4cccc(OC)c4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L14 compound treatment 0.391 0.0444 3.69 0.375 0.0342 3.03 4.7492 0.9953 1941379 CBMicro_031592 ClC1=C(Nc2ccccc2)C(=O)N(C1=O)c3cccc(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L15 compound treatment 0.358 0.0114 0.95 0.348 0.00719 0.64 1.12 0.9815 1439318 CBMicro_031593 CC(C)OC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L16 compound treatment 0.364 0.0174 1.44 0.364 0.0232 2.06 2.4749 0.9851 1941380 CBMicro_031594 CCOCCOC(=O)c1ccc(NC(=O)COc2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L17 compound treatment 0.384 0.0374 3.1 0.373 0.0322 2.85 4.2129 0.9991 1435828 CBMicro_031595 CC(Oc1ccc2c3CCCCc3c(=O)oc2c1)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L18 compound treatment 0.314 -0.0326 -2.71 0.32 -0.0208 -1.84 -3.2176 -0.9825 1941381 CBMicro_031596 CCCCOC(=O)c1cccc(NC(=O)COc2ccc(C)cc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L19 compound treatment 0.376 0.0294 2.44 0.36 0.0192 1.7 2.9286 0.9844 1941382 CBMicro_031597 O=c1oc2cc(OC/C=C/c3ccccc3)ccc2c4CCCCc41 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L20 compound treatment 0.369 0.0224 1.86 0.364 0.0232 2.06 2.7684 0.9988 1557745 CBMicro_031598 Cc1ccc(OCC(=O)Nc2nccs2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L21 compound treatment 0.36 0.0134 1.11 0.341 1.94E-4 0.02 0.7988 0.7179 1409154 CBMicro_031599 COc1ccccc1c2coc3cc(OC(=O)c4ccccc4C)ccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L22 compound treatment 0.348 0.0014 0.12 0.341 1.94E-4 0.02 0.0943 0.8028 1449955 CBMicro_031600 COc1cc(cc(OC)c1OC)C(=O)Nc2c(cccc2C(C)C)C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L23 positive control 0.092 -0.255 -21.14 0.087 -0.254 -22.49 -30.8507 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 L24 positive control 0.098 -0.249 -20.64 0.092 -0.249 -22.05 -30.1851 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M01 mock treatment 0.343 -0.0036 -0.3 0.341 1.94E-4 0.02 -0.1992 -0.6654 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M02 mock treatment 0.343 -0.0036 -0.3 0.34 -8.06E-4 -0.07 -0.2619 -0.8522 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M03 compound treatment 0.348 0.0014 0.12 0.339 -0.00181 -0.16 -0.031 -0.1568 1457473 CBMicro_031601 Cc1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)c(c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M04 compound treatment 0.353 0.0064 0.53 0.341 1.94E-4 0.02 0.3878 0.7296 1941383 CBMicro_031602 COc1cc(/C=N/n2cnnc2)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M05 compound treatment 0.342 -0.0046 -0.38 0.341 1.94E-4 0.02 -0.2579 -0.6747 1941384 CBMicro_031603 FC(F)(F)c1cccc(N/C=C/C(=O)c2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M06 compound treatment 0.34 -0.0066 -0.55 0.336 -0.00481 -0.43 -0.6886 -0.9922 1145366 CBMicro_031604 COc1cccc(c1)N(CC(=O)Nc2cc(C)ccc2C)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M07 compound treatment 0.353 0.0064 0.53 0.34 -8.06E-4 -0.07 0.3252 0.6065 1276010 CBMicro_031605 Cc1ccc(OCC(=O)Nc2ccc(C)cc2Br)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M08 compound treatment 0.351 0.0044 0.37 0.339 -0.00181 -0.16 0.1451 0.3638 1941385 CBMicro_031606 CCOc1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M09 compound treatment 0.412 0.0654 5.43 0.403 0.0622 5.51 7.7366 1.0 1941386 CBMicro_031607 OC(=O)c1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M10 compound treatment 0.407 0.0604 5.01 0.387 0.0462 4.09 6.4404 0.9949 1941387 CBMicro_031608 OC(=O)CCN1C(=O)/C(=C/2\C(=O)N(Cc3ccccc3Cl)c4ccccc24)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M11 compound treatment 0.354 0.0074 0.61 0.339 -0.00181 -0.16 0.3212 0.5059 1941388 CBMicro_031609 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(Cl)cc3Cl)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M12 compound treatment 0.367 0.0204 1.69 0.365 0.0242 2.14 2.7136 0.9932 1941389 CBMicro_031610 CN1C(=O)/C(=C\c2cc(Cl)ccc2OCc3ccccc3Cl)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M13 compound treatment 0.338 -0.0086 -0.71 0.331 -0.00981 -0.87 -1.1194 -0.9952 1941390 CBMicro_031611 COC(=O)c1ccccc1c2ccc(/C=C\3/SC(=S)NC3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M14 compound treatment 0.343 -0.0036 -0.3 0.33 -0.0108 -0.96 -0.8885 -0.8857 1668599 CBMicro_031612 COc1cccc(c1)C(=O)Nc2cccc3C(=O)N(C(=O)c32)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M15 compound treatment 0.265 -0.0816 -6.77 0.277 -0.0638 -5.65 -8.7886 -0.996 1941391 CBMicro_031613 Cc1cccc(OCCOc2ccc(/C=N/N3C(=O)CSC3=S)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M16 compound treatment 0.346 -6.0E-4 -0.05 0.348 0.00719 0.64 0.4156 0.6499 1941392 CBMicro_031614 COc1ccc(CCNC=C2C(=O)CC(CC2=O)c3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M17 compound treatment 0.363 0.0164 1.36 0.346 0.00519 0.46 1.2882 0.8963 1941393 CBMicro_031615 CC(C)(C)c1ccc(OCCOc2ccc(Cl)cc2/C=N/n3cnnc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M18 compound treatment 0.385 0.0384 3.19 0.398 0.0572 5.07 5.8382 0.975 1941394 CBMicro_031616 CC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccccc3)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M19 compound treatment 0.341 -0.0056 -0.46 0.332 -0.00881 -0.78 -0.8806 -0.9694 1941395 CBMicro_031617 CCc1cc(=O)oc2cc(OC)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M20 compound treatment 0.328 -0.0186 -1.54 0.327 -0.0138 -1.22 -1.9571 -0.9934 1497715 CBMicro_031618 Fc1ccc(CNC2=CC(=O)CC(C2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M21 compound treatment 0.336 -0.0106 -0.88 0.327 -0.0138 -1.22 -1.4874 -0.9869 1398873 CBMicro_031619 COc1cccc(NC(=O)COc2cccc(C)c2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M22 compound treatment 0.352 0.0054 0.45 0.354 0.0132 1.17 1.1438 0.9134 1570143 CBMicro_031620 CC(=O)Oc1cccc(c1)C(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M23 positive control 0.093 -0.254 -21.05 0.087 -0.254 -22.49 -30.792 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 M24 positive control 0.096 -0.251 -20.8 0.094 -0.247 -21.87 -30.1772 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N01 mock treatment 0.354 0.0074 0.61 0.344 0.00319 0.28 0.6345 0.9381 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N02 mock treatment 0.354 0.0074 0.61 0.349 0.00819 0.73 0.9479 0.9965 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N03 compound treatment 0.344 -0.0026 -0.22 0.337 -0.00381 -0.34 -0.3912 -0.9767 1941396 CBMicro_031621 COC(=O)Nc1sc(C)c(C)c1C(=O)N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N04 compound treatment 0.346 -6.0E-4 -0.05 0.333 -0.00781 -0.69 -0.5244 -0.7561 1941397 CBMicro_031622 CC(C)CC(=O)Nc1ccc(F)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N05 compound treatment 0.356 0.0094 0.78 0.351 0.0102 0.9 1.1906 0.9973 1135502 CBMicro_031623 COC(=O)c1c(NC(=O)C2CCCCC2C(=O)O)scc1c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N06 compound treatment 0.367 0.0204 1.69 0.371 0.0302 2.68 3.0896 0.9757 1941398 CBMicro_031624 [O-][N+](=O)c1cccc(c1)C(=O)NC(NC(=S)Nc2c(Cl)cccc2Cl)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N07 compound treatment 0.344 -0.0026 -0.22 0.331 -0.00981 -0.87 -0.7672 -0.8567 1941399 CBMicro_031625 Fc1ccc(cc1)S(=O)(=O)n2cccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N08 compound treatment 0.349 0.0024 0.2 0.324 -0.0168 -1.49 -0.9123 -0.6071 1941400 CBMicro_031626 COc1ccc(OC)c(NC(=S)NC(NC(=O)c2ccc(Cl)cc2Cl)C(Cl)(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N09 compound treatment 0.349 0.0024 0.2 0.336 -0.00481 -0.43 -0.1603 -0.3409 1594928 CBMicro_031627 Cc1ccc(cc1)c2nnc(o2)c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N10 compound treatment 0.358 0.0114 0.95 0.354 0.0132 1.17 1.496 0.9945 1941401 CBMicro_031628 [O-][N+](=O)c1cccc(NC(NC(=O)c2cccc(I)c2)C(Cl)(Cl)Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N11 compound treatment 0.358 0.0114 0.95 0.342 0.00119 0.11 0.744 0.7813 1941402 CBMicro_031629 CCOC(=O)C1=NNC(C1c2ccc(OC)cc2)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N12 compound treatment 0.417 0.0704 5.84 0.423 0.0822 7.28 9.2834 0.994 1941403 CBMicro_031630 COC(=O)CN1C(=O)/C(=C\c2cccc(c2)[N+](=O)[O-])/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N13 compound treatment 0.347 4.0E-4 0.03 0.346 0.00519 0.46 0.3489 0.7562 1379212 CBMicro_031631 Cc1ccc(cc1)N2C(=O)C3CC=C(CC3C2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N14 compound treatment 0.37 0.0234 1.94 0.355 0.0142 1.26 2.2631 0.9779 1190092 CBMicro_031632 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccccc3F)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N15 compound treatment 0.352 0.0054 0.45 0.342 0.00119 0.11 0.3918 0.8506 1941404 CBMicro_031633 COc1ccc2c(=O)c(c3ccccc3OC)c(oc2c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N16 compound treatment 0.373 0.0264 2.19 0.371 0.0302 2.68 3.4418 0.9951 1284172 CBMicro_031634 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2cc(C)ccc2C(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N17 compound treatment 0.353 0.0064 0.53 0.356 0.0152 1.35 1.3278 0.9173 1454651 CBMicro_031635 CCOc1cc(C)cc2oc(=O)c3CCCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N18 compound treatment 0.382 0.0354 2.94 0.377 0.0362 3.21 4.3462 0.999 1941405 CBMicro_031636 CCc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N19 compound treatment 0.347 4.0E-4 0.03 0.341 1.94E-4 0.02 0.0356 0.9528 1624475 CBMicro_031637 Cc1c(OCC(=O)OCc2ccccc2)ccc3c4CCCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N20 compound treatment 0.352 0.0054 0.45 0.346 0.00519 0.46 0.6425 0.9999 1941406 CBMicro_031638 Oc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1CN4CCCC4)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N21 compound treatment 0.348 0.0014 0.12 0.346 0.00519 0.46 0.4076 0.8587 1504528 CBMicro_031639 CC(C)OC(=O)COc1cc2oc(=O)c3CCCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N22 compound treatment 0.361 0.0144 1.2 0.348 0.00719 0.64 1.2961 0.9567 1941407 CBMicro_031640 COC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N23 positive control 0.09 -0.257 -21.3 0.088 -0.253 -22.4 -30.9054 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 N24 positive control 0.094 -0.253 -20.97 0.092 -0.249 -22.05 -30.4199 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O01 mock treatment 0.347 4.0E-4 0.03 0.346 0.00519 0.46 0.3489 0.7562 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O02 mock treatment 0.36 0.0134 1.11 0.352 0.0112 0.99 1.4881 0.9984 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O03 compound treatment 0.343 -0.0036 -0.3 0.335 -0.00581 -0.51 -0.5752 -0.9666 1531705 CBMicro_031641 CC(C)COC(=O)c1ccc(NC(=O)COc2ccc(C)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O04 compound treatment 0.343 -0.0036 -0.3 0.334 -0.00681 -0.6 -0.6379 -0.9475 1941408 CBMicro_031642 Cc1ccc(CNC(=O)C(=O)Nc2ccccc2Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O05 compound treatment 0.336 -0.0106 -0.88 0.337 -0.00381 -0.34 -0.8608 -0.9134 1941409 CBMicro_031643 Clc1cc(N/C=C/C(=O)c2ccccc2)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O06 compound treatment 0.357 0.0104 0.86 0.35 0.00919 0.81 1.1866 0.9996 1412457 CBMicro_031644 COc1cccc(c1)N(CC(=O)Nc2ccc(OC)cc2OC)S(=O)(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O07 compound treatment 0.34 -0.0066 -0.55 0.332 -0.00881 -0.78 -0.9393 -0.985 1941410 CBMicro_031645 COC(=O)CN1C(=O)/C(=C/c2cccc(OCc3ccccc3)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O08 compound treatment 0.34 -0.0066 -0.55 0.338 -0.00281 -0.25 -0.5633 -0.9361 1941411 CBMicro_031646 Brc1ccc(OCCOc2cccc(/C=N/n3cnnc3)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O09 compound treatment 0.34 -0.0066 -0.55 0.33 -0.0108 -0.96 -1.0646 -0.9649 1151567 CBMicro_031647 CC(C)C(=O)Oc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O10 compound treatment 0.394 0.0474 3.94 0.375 0.0342 3.03 4.9253 0.9917 1518994 CBMicro_031648 CCOc1ccc(NC(=O)CN(c2ccc(OC)cc2OC)S(=O)(=O)c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O11 compound treatment 0.364 0.0174 1.44 0.358 0.0172 1.52 2.0989 0.9996 1941412 CBMicro_031649 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(Cl)cc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O12 compound treatment 0.352 0.0054 0.45 0.346 0.00519 0.46 0.6425 0.9999 1941413 CBMicro_031650 COCCNC(=O)CN(c1cccc(OC)c1)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O13 compound treatment 0.341 -0.0056 -0.46 0.333 -0.00781 -0.69 -0.8179 -0.9813 1941414 CBMicro_031651 CCOc1ccc(/C=C\2/NC(=O)NC2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O14 compound treatment 0.369 0.0224 1.86 0.36 0.0192 1.7 2.5177 0.999 1625562 CBMicro_031652 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4cccc(C)c4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O15 compound treatment 0.341 -0.0056 -0.46 0.343 0.00219 0.19 -0.1913 -0.3796 1646368 CBMicro_031653 COc1ccc(cc1)N(CC(=O)Nc2ccccc2C)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O16 compound treatment 0.351 0.0044 0.37 0.348 0.00719 0.64 0.7091 0.9651 1274192 CBMicro_031654 COc1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cccc(O)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O17 compound treatment 0.362 0.0154 1.28 0.353 0.0122 1.08 1.6681 0.9965 1484787 CBMicro_031655 Cc1ccc(NC(=O)CN(c2cc(Cl)cc(Cl)c2)S(=O)(=O)C)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O18 compound treatment 0.349 0.0024 0.2 0.344 0.00319 0.28 0.341 0.9852 1636531 CBMicro_031656 Clc1ccc(cc1Cl)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O19 compound treatment 0.332 -0.0146 -1.21 0.322 -0.0188 -1.67 -2.0356 -0.9878 1370778 CBMicro_031657 Oc1ccc(C(=O)Cc2ccccc2Cl)c(O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O20 compound treatment 0.378 0.0314 2.61 0.354 0.0132 1.17 2.6701 0.9346 1941415 CBMicro_031658 [O-][N+](=O)c1ccc(cc1)n2cccc2/C=N/NC(=O)c3cc(n[nH]3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O21 compound treatment 0.348 0.0014 0.12 0.348 0.00719 0.64 0.533 0.8225 1292729 CBMicro_031659 COc1ccccc1OCC(=O)Nc2c(C)cccc2C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O22 compound treatment 0.339 -0.0076 -0.63 0.334 -0.00681 -0.6 -0.8727 -0.9997 1941416 CBMicro_031660 Cc1cc([nH]n1)C(=O)N/N=C\c2cc(Br)ccc2OCc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O23 positive control 0.089 -0.258 -21.39 0.089 -0.252 -22.32 -30.9014 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 O24 positive control 0.095 -0.252 -20.89 0.094 -0.247 -21.87 -30.2359 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P01 mock treatment 0.346 -6.0E-4 -0.05 0.34 -8.06E-4 -0.07 -0.0858 -0.9844 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P02 mock treatment 0.356 0.0094 0.78 0.346 0.00519 0.46 0.8773 0.9683 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P03 compound treatment 0.531 0.184 15.31 0.377 0.0362 3.21 13.093 0.8371 1941417 CBMicro_031661 COC(=O)c1c(NC(=O)/C=C/C(=O)O)sc2CC(CCc12)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P04 compound treatment 0.341 -0.0056 -0.46 0.338 -0.00281 -0.25 -0.5046 -0.957 1941418 CBMicro_031662 CC(C)CC(=O)Nc1cccc(Cl)c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P05 compound treatment 0.335 -0.0116 -0.96 0.34 -8.06E-4 -0.07 -0.7315 -0.7575 1941419 CBMicro_031663 COc1ccc(cc1)S(=O)(=O)n2cccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P06 compound treatment 0.374 0.0274 2.27 0.381 0.0402 3.56 4.1272 0.9765 1941420 CBMicro_031664 COc1cc(cc(OC)c1OC)C(=O)NC(NC(=S)Nc2ccc(C)cc2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P07 compound treatment 0.343 -0.0036 -0.3 0.335 -0.00581 -0.51 -0.5752 -0.9666 1645034 CBMicro_031665 COC(=O)c1c(N)scc1c2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P08 compound treatment 0.391 0.0444 3.69 0.392 0.0512 4.54 5.8145 0.9947 1941421 CBMicro_031666 CCOC(=O)c1ccc(NC(=S)NC(NC(=O)c2ccc(C)cc2)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P09 compound treatment 0.361 0.0144 1.2 0.359 0.0182 1.61 1.9854 0.9892 1941422 CBMicro_031667 CC(C)(C)C1CCC(CC1)C(=O)N/N=C/c2cc(ccc2O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P10 compound treatment 0.361 0.0144 1.2 0.354 0.0132 1.17 1.6721 0.9999 1941423 CBMicro_031668 CC(=O)c1ccc(NC(=S)NC(NC(=O)c2ccccc2Br)C(Cl)(Cl)Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P11 compound treatment 0.346 -6.0E-4 -0.05 0.348 0.00719 0.64 0.4156 0.6499 1309593 CBMicro_031669 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccc(Cl)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P12 compound treatment 0.355 0.0084 0.7 0.344 0.00319 0.28 0.6932 0.9211 1941424 CBMicro_031670 CCOC(=O)C(=CNc1ccc(O)cc1)C(=O)OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P13 compound treatment 0.358 0.0114 0.95 0.354 0.0132 1.17 1.496 0.9945 1537787 CBMicro_031671 Cc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P14 compound treatment 0.337 -0.0096 -0.8 0.342 0.00119 0.11 -0.4888 -0.6079 1168663 CBMicro_031672 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3ccccc3C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P15 compound treatment 0.348 0.0014 0.12 0.339 -0.00181 -0.16 -0.031 -0.1568 1623985 CBMicro_031673 COc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3)c(Br)c(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P16 compound treatment 0.337 -0.0096 -0.8 0.341 1.94E-4 0.02 -0.5514 -0.6917 1941425 CBMicro_031674 COC(=O)c1ccc(NC(=O)CCCOc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P17 compound treatment 0.348 0.0014 0.12 0.348 0.00719 0.64 0.533 0.8225 1941426 CBMicro_031675 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P18 compound treatment 0.341 -0.0056 -0.46 0.335 -0.00581 -0.51 -0.6926 -0.9987 1304608 CBMicro_031676 OC(=O)CCC(=O)N1N=C(CC1c2cccs2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P19 compound treatment 0.344 -0.0026 -0.22 0.334 -0.00681 -0.6 -0.5792 -0.904 1941427 CBMicro_031677 COc1ccc(cc1OC)C(=O)Oc2ccc3c(C)cc(=O)oc3c2C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P20 compound treatment 0.346 -6.0E-4 -0.05 0.338 -0.00281 -0.25 -0.2111 -0.8322 1941428 CBMicro_031678 Fc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P21 compound treatment 0.346 -6.0E-4 -0.05 0.341 1.94E-4 0.02 -0.0231 -0.4384 1262857 CBMicro_031679 Cc1c(OCC(=O)c2ccc(F)cc2)ccc3c4CCCCc4c(=O)oc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P22 compound treatment 0.491 0.144 11.99 0.448 0.107 9.5 15.194 0.9934 1941429 CBMicro_031680 CCCCOc1ccc(/C=C/2\SC(=S)N(C(C)C(=O)O)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P23 positive control 0.091 -0.256 -21.22 0.092 -0.249 -22.05 -30.596 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.784 P24 positive control 0.095 -0.252 -20.89 0.093 -0.248 -21.96 -30.2986 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A01 mock treatment 0.319 -0.0144 -1.2 0.333 -0.00394 -0.35 -1.0931 -0.8767 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A02 mock treatment 0.332 -0.00142 -0.12 0.342 0.00506 0.45 0.234 0.5044 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A03 compound treatment 0.319 -0.0144 -1.2 0.332 -0.00494 -0.44 -1.1557 -0.9068 1941430 CBMicro_031681 Cc1cc(/C=C\2/NC(=O)NC2=O)c(c3ccccc3)n1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A04 compound treatment 0.319 -0.0144 -1.2 0.332 -0.00494 -0.44 -1.1557 -0.9068 1271917 CBMicro_031682 CC(=O)N(Cc1ccco1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A05 compound treatment 0.332 -0.00142 -0.12 0.34 0.00306 0.27 0.1087 0.3672 1941431 CBMicro_031683 CCOc1cc(/C=N/n2cnnc2)cc(Br)c1OCCOc3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A06 compound treatment 0.315 -0.0184 -1.53 0.327 -0.00994 -0.88 -1.7039 -0.9656 1941432 CBMicro_031684 [O-][N+](=O)c1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4c[nH]c(=O)[nH]c4=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A07 compound treatment 0.343 0.00958 0.8 0.356 0.0191 1.69 1.7571 0.9409 1467453 CBMicro_031685 Brc1ccc(o1)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A08 compound treatment 0.325 -0.00842 -0.7 0.338 0.00106 0.09 -0.4275 -0.6062 1941433 CBMicro_031686 CC(=O)c1cccc(NC(=O)Nc2ccccc2C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A09 compound treatment 0.328 -0.00542 -0.45 0.339 0.00206 0.18 -0.1888 -0.3886 1288605 CBMicro_031687 OC(=O)CCC(=O)Nc1cccc(c1)c2nc3cc4ccccc4cc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A10 compound treatment 0.416 0.0826 6.86 0.423 0.0861 7.63 10.241 0.9986 1941434 CBMicro_031688 CC(CO)(CO)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A11 compound treatment 0.322 -0.0114 -0.95 0.335 -0.00194 -0.17 -0.7916 -0.8217 1941435 CBMicro_031689 CCOC(=O)C1=C(Nc2ccccc2)SCC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A12 compound treatment 0.314 -0.0194 -1.61 0.328 -0.00894 -0.79 -1.6999 -0.9464 1474337 CBMicro_031690 COc1cccc(c1)C(=O)Nc2cccc(C#C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A13 compound treatment 0.328 -0.00542 -0.45 0.341 0.00406 0.36 -0.0634 -0.1101 1522570 CBMicro_031691 CCOc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4cc(C)c(C)cc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A14 compound treatment 0.32 -0.0134 -1.11 0.315 -0.0219 -1.94 -2.1623 -0.9651 1578384 CBMicro_031692 CCCc1cc(=O)oc2cc(OCc3ccccc3Cl)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A15 compound treatment 0.531 0.198 16.4 0.52 0.183 16.22 23.0704 1.0 1941436 CBMicro_031693 COc1cc(/C=C/2\SC(=O)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A16 compound treatment 0.268 -0.0654 -5.43 0.28 -0.0569 -5.05 -7.4082 -0.9993 1941437 CBMicro_031694 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3[N+](=O)[O-])C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A17 compound treatment 0.331 -0.00242 -0.2 0.33 -0.00694 -0.61 -0.5766 -0.8918 1381176 CBMicro_031695 CCOC(=O)COc1cc(C)c2c(=O)c(coc2c1)c3nc(C)cs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A18 compound treatment 0.339 0.00558 0.46 0.332 -0.00494 -0.44 0.0183 0.0288 1941438 CBMicro_031696 O=C(N/N=C/c1ccc(OC(=O)c2cccnc2)cc1)C3COc4ccccc4O3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A19 compound treatment 0.402 0.0686 5.69 0.401 0.0641 5.68 8.0405 1.0 1356508 CBMicro_031697 Cc1cccc(N2C(=O)c3ccc(N)cc3C2=O)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A20 compound treatment 0.324 -0.00942 -0.78 0.331 -0.00594 -0.53 -0.9249 -0.9814 1643602 CBMicro_031698 O=S(=O)(NCC(N1CCNCC1)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A21 compound treatment 0.32 -0.0134 -1.11 0.324 -0.0129 -1.15 -1.5984 -0.9999 1239774 CBMicro_031699 COc1cccc(c1)C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A22 compound treatment 0.33 -0.00342 -0.28 0.322 -0.0149 -1.32 -1.1367 -0.8397 1941439 CBMicro_031700 Clc1ccc2c(=O)oc(nc2c1)c3cccs3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A23 positive control 0.082 -0.251 -20.87 0.083 -0.254 -22.5 -30.672 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 A24 positive control 0.084 -0.249 -20.71 0.088 -0.249 -22.06 -30.2413 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B01 mock treatment 0.33 -0.00342 -0.28 0.327 -0.00994 -0.88 -0.8233 -0.89 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B02 mock treatment 0.335 0.00158 0.13 0.336 -9.35E-4 -0.08 0.0342 0.2201 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B03 compound treatment 0.328 -0.00542 -0.45 0.33 -0.00694 -0.61 -0.7527 -0.9882 1409057 CBMicro_031701 O=C1CCCCC1Oc2ccc3c4CCCc4c(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B04 compound treatment 0.317 -0.0164 -1.36 0.315 -0.0219 -1.94 -2.3385 -0.9849 1549694 CBMicro_031702 Clc1ccc(cc1)c2nc(NCC=C)c3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B05 compound treatment 0.323 -0.0104 -0.87 0.335 -0.00194 -0.17 -0.7329 -0.8311 1941440 CBMicro_031703 COc1ccc2n(C)c(C)c(/C=C/c3nc4ccccc4c(=O)n3c5cccc(c5)[N+](=O)[O-])c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B06 compound treatment 0.326 -0.00742 -0.62 0.323 -0.0139 -1.23 -1.3088 -0.9484 1291603 CBMicro_031704 COc1ccc2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B07 compound treatment 0.192 -0.141 -11.74 0.193 -0.144 -12.76 -17.3215 -0.9991 1941441 CBMicro_031705 Cc1ccc(/C=C/C(=O)NCCc2ccccc2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B08 compound treatment 0.328 -0.00542 -0.45 0.33 -0.00694 -0.61 -0.7527 -0.9882 1412176 CBMicro_031706 CC1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B09 compound treatment 0.325 -0.00842 -0.7 0.327 -0.00994 -0.88 -1.1169 -0.9935 1941442 CBMicro_031707 C/C(=N\NC(=O)C1(C)CC1(Br)Br)/c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B10 compound treatment 0.372 0.0386 3.2 0.356 0.0191 1.69 3.4595 0.9553 1941443 CBMicro_031708 Fc1ccc(N/C=C/C(=O)c2ccc(Br)cc2)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B11 compound treatment 0.345 0.0116 0.96 0.34 0.00306 0.27 0.8719 0.8727 1470739 CBMicro_031709 CC(C)OC(=O)c1c(NC(=O)C2C(C3CCC2C3)C(=O)O)sc4CCCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B12 compound treatment 0.349 0.0156 1.29 0.372 0.0351 3.11 3.112 0.9245 1609804 CBMicro_031710 CCc1ccccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B13 compound treatment 0.327 -0.00642 -0.53 0.335 -0.00194 -0.17 -0.4981 -0.8897 1941444 CBMicro_031711 Cc1ccc(NC(=O)CC2CCCCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B14 compound treatment 0.316 -0.0174 -1.45 0.325 -0.0119 -1.06 -1.7705 -0.9882 1941445 CBMicro_031712 [O-][N+](=O)c1ccc(OCc2ccccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B15 compound treatment 0.35 0.0166 1.38 0.351 0.0141 1.25 1.8547 0.9988 1420416 CBMicro_031713 Cc1cccc(OCC(=O)Nc2ccc(Cl)c(Cl)c2)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B16 compound treatment 0.329 -0.00442 -0.37 0.322 -0.0149 -1.32 -1.1954 -0.8703 1941446 CBMicro_031714 COc1ccc(cc1OC)C(=O)NC(N2CCCCC2)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B17 compound treatment 0.366 0.0326 2.7 0.37 0.0331 2.93 3.9846 0.9992 1186324 CBMicro_031715 CC(Oc1cc2oc(=O)c3CCCCc3c2cc1Cl)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B18 compound treatment 0.33 -0.00342 -0.28 0.335 -0.00194 -0.17 -0.322 -0.9709 1941447 CBMicro_031716 CCOC(=O)C1=NNC(C1c2ccc(Br)cc2)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B19 compound treatment 0.341 0.00758 0.63 0.342 0.00506 0.45 0.7624 0.9863 1941448 CBMicro_031717 O=C/1OC(=C\C1=C\c2ccco2)c3ccc(Oc4ccccc4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B20 compound treatment 0.325 -0.00842 -0.7 0.323 -0.0139 -1.23 -1.3675 -0.9637 1524635 CBMicro_031718 O=C(NCc1ccc2OCOc2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B21 compound treatment 0.317 -0.0164 -1.36 0.317 -0.0199 -1.77 -2.2131 -0.9918 1466687 CBMicro_031719 CC(C)CNc1nc(nc2ccccc12)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B22 compound treatment 0.335 0.00158 0.13 0.335 -0.00194 -0.17 -0.0285 -0.132 1511360 CBMicro_031720 COC(=O)C1CSC(CC(=O)Nc2sc3CCCCc3c2C(=O)OC)C(=O)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B23 positive control 0.082 -0.251 -20.87 0.086 -0.251 -22.24 -30.484 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 B24 positive control 0.083 -0.25 -20.79 0.093 -0.244 -21.62 -29.9867 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C01 mock treatment 0.336 0.00258 0.21 0.333 -0.00394 -0.35 -0.0951 -0.2324 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C02 mock treatment 0.349 0.0156 1.29 0.338 0.00106 0.09 0.9813 0.7567 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C03 compound treatment 0.316 -0.0174 -1.45 0.339 0.00206 0.18 -0.8932 -0.6128 1941449 CBMicro_031721 Clc1ccccc1Cn2cc(/C=C\3/SC(=S)N(CC=C)C3=O)c4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C04 compound treatment 0.348 0.0146 1.21 0.352 0.0151 1.34 1.8 0.9988 1941450 CBMicro_031722 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3c(OC)ccc4ccccc34)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C05 compound treatment 0.348 0.0146 1.21 0.347 0.0101 0.89 1.4866 0.9887 1382345 CBMicro_031723 COc1ccc(OC)c(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C06 compound treatment 0.342 0.00858 0.71 0.336 -9.35E-4 -0.08 0.4451 0.6206 1355291 CBMicro_031724 CC(C)c1ccccc1OCC(=O)Nc2cccc(c2)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C07 compound treatment 0.375 0.0416 3.45 0.375 0.0381 3.37 4.8262 0.9999 1172201 CBMicro_031725 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C08 compound treatment 0.343 0.00958 0.8 0.35 0.0131 1.16 1.3811 0.9832 1634773 CBMicro_031726 COc1ccc(CCN(C2CC(=O)N(C2=O)c3ccccc3)C(=S)Nc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C09 compound treatment 0.323 -0.0104 -0.87 0.324 -0.0129 -1.15 -1.4223 -0.9904 1941451 CBMicro_031727 [O-][N+](=O)c1ccccc1NC(=O)C2COc3ccccc3O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C10 compound treatment 0.349 0.0156 1.29 0.343 0.00606 0.54 1.2947 0.9243 1325851 CBMicro_031728 Cc1ccc2oc(nc2c1)c3ccc(C)c(NC(=O)c4ccc(Br)o4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C11 compound treatment 0.348 0.0146 1.21 0.353 0.0161 1.42 1.8626 0.9967 1941452 CBMicro_031729 COc1cc(OC)c(/C=N/NC(=O)CSc2nc3ccccc3[nH]2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C12 compound treatment 0.439 0.106 8.77 0.427 0.0901 7.98 11.8418 0.9989 1941453 CBMicro_031730 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C13 compound treatment 0.33 -0.00342 -0.28 0.328 -0.00894 -0.79 -0.7607 -0.9042 1546904 CBMicro_031731 Cc1cccc(C(=O)O)c1NC(=O)c2cccc(F)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C14 compound treatment 0.356 0.0226 1.87 0.348 0.0111 0.98 2.0189 0.9543 1398153 CBMicro_031732 Clc1ccccc1COc2ccc3c(=O)c(coc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C15 compound treatment 0.357 0.0236 1.96 0.358 0.0211 1.87 2.7043 0.9997 1941454 CBMicro_031733 Fc1ccc(/C=C/2\NC(=S)NC2=O)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C16 compound treatment 0.328 -0.00542 -0.45 0.327 -0.00994 -0.88 -0.9407 -0.9514 1941455 CBMicro_031734 [O-][N+](=O)c1ccc2C(=O)N(CC(=O)NN3C(=O)c4ccccc4C3=O)C(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C17 compound treatment 0.404 0.0706 5.86 0.387 0.0501 4.44 7.2806 0.9906 1941456 CBMicro_031735 Oc1cccc(c1)N2C(=O)S/C(=C/3\C(=O)Nc4ccccc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C18 compound treatment 0.345 0.0116 0.96 0.356 0.0191 1.69 1.8745 0.9643 1781934 CBMicro_031736 CCN1C(=C(C(NC1=O)c2ccccc2[N+](=O)[O-])C(=O)OC3CCCCC3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C19 compound treatment 0.815 0.482 39.98 0.764 0.427 37.85 55.0324 0.9996 1941457 CBMicro_031737 Cc1ccc(/C=C\2/SC(=S)N(CCC(=O)O)C2=O)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C20 compound treatment 0.338 0.00458 0.38 0.336 -9.35E-4 -0.08 0.2103 0.5403 1198798 CBMicro_031738 CCOC(=O)C1=C(C)NC(=C(C1c2cccs2)C(=O)OCC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C21 compound treatment 0.344 0.0106 0.88 0.337 6.45E-5 0.01 0.6252 0.7117 1680048 CBMicro_031739 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cc(ccc4C)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C22 compound treatment 0.331 -0.00242 -0.2 0.326 -0.0109 -0.97 -0.8273 -0.8359 1941458 CBMicro_031740 Cc1cc([nH]n1)C(=O)N/N=C/2\C(=O)N(Cc3ccccc3)c4ccc(Br)cc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C23 positive control 0.081 -0.252 -20.96 0.082 -0.255 -22.59 -30.7934 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 C24 positive control 0.089 -0.244 -20.29 0.093 -0.244 -21.62 -29.6345 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D01 mock treatment 0.332 -0.00142 -0.12 0.336 -9.35E-4 -0.08 -0.1419 -0.9852 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D02 mock treatment 0.342 0.00858 0.71 0.338 0.00106 0.09 0.5704 0.7938 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D03 compound treatment 0.35 0.0166 1.38 0.352 0.0151 1.34 1.9174 0.9999 1656687 CBMicro_031741 COc1ccc2nc(NC(=S)NC(=O)c3ccco3)sc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D04 compound treatment 0.314 -0.0194 -1.61 0.311 -0.0259 -2.3 -2.7652 -0.9849 1148370 CBMicro_031742 CC(C)CNc1nc(nc2ccccc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D05 compound treatment 0.286 -0.0474 -3.94 0.294 -0.0429 -3.81 -5.4742 -0.9999 1941459 CBMicro_031743 CCC1(C)CC(CCNCc2ccc(cc2)N(C)C)(CCO1)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D06 compound treatment 0.359 0.0256 2.12 0.357 0.0201 1.78 2.759 0.9961 1941460 CBMicro_031744 [O-][N+](=O)c1ccccc1OC(=O)COc2ccc(Cl)cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D07 compound treatment 0.348 0.0146 1.21 0.36 0.0231 2.04 2.3013 0.9687 1941461 CBMicro_031745 [O-][N+](=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)c(Cl)c4)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D08 compound treatment 0.348 0.0146 1.21 0.342 0.00506 0.45 1.1733 0.9088 1241372 CBMicro_031746 O=C(Cc1ccccc1)Oc2cccc3c(OC(=O)Cc4ccccc4)cccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D09 compound treatment 0.327 -0.00642 -0.53 0.322 -0.0149 -1.32 -1.3128 -0.92 1454188 CBMicro_031747 CCc1cccc(C)c1NC(=O)C2C(C3CCC2O3)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D10 compound treatment 0.328 -0.00542 -0.45 0.326 -0.0109 -0.97 -1.0034 -0.9391 1941462 CBMicro_031748 ClC1(Cl)CC1(C(=O)NCC=C)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D11 compound treatment 0.342 0.00858 0.71 0.341 0.00406 0.36 0.7584 0.9501 1941463 CBMicro_031749 NNC(=O)c1sc2cccc(Cl)c2c1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D12 compound treatment 0.344 0.0106 0.88 0.342 0.00506 0.45 0.9385 0.9514 1941464 CBMicro_031750 Cc1ccccc1OCCOc2ccc(Cl)cc2/C=N/n3cnnc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D13 compound treatment 0.343 0.00958 0.8 0.352 0.0151 1.34 1.5064 0.9694 1675621 CBMicro_031751 NC1=C(C(=O)CN1c2ccc3OCOc3c2)c4nc5ccccc5c(=O)[nH]4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D14 compound treatment 0.346 0.0126 1.04 0.336 -9.35E-4 -0.08 0.6799 0.6489 1404399 CBMicro_031752 OC(=O)C(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D15 compound treatment 0.314 -0.0194 -1.61 0.321 -0.0159 -1.41 -2.1386 -0.9978 1941465 CBMicro_031753 Cc1cccc(NC(=O)CCCOc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D16 compound treatment 0.341 0.00758 0.63 0.346 0.00906 0.8 1.013 0.9927 1419749 CBMicro_031754 CCOc1ccc(cc1)c2cc(C(=O)NN)c3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D17 compound treatment 0.33 -0.00342 -0.28 0.331 -0.00594 -0.53 -0.5727 -0.9581 1941466 CBMicro_031755 CCCOc1ccc2c3CCCCc3c(=O)oc2c1OCCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D18 compound treatment 0.332 -0.00142 -0.12 0.33 -0.00694 -0.61 -0.5179 -0.8276 1219300 CBMicro_031756 CC1CN(CC(C)O1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D19 compound treatment 0.331 -0.00242 -0.2 0.332 -0.00494 -0.44 -0.4513 -0.9377 1941467 CBMicro_031757 Clc1cccc(Cl)c1/C=C/2\C=C(OC2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D20 compound treatment 0.353 0.0196 1.63 0.356 0.0191 1.69 2.3441 0.9998 1612072 CBMicro_031758 CCCOc1cc2oc(=O)c3CCCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D21 compound treatment 0.337 0.00358 0.3 0.329 -0.00794 -0.7 -0.2871 -0.376 1617687 CBMicro_031759 CC1CCCN(C1)C(=O)c2ccccc2NC(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D22 compound treatment 0.33 -0.00342 -0.28 0.329 -0.00794 -0.7 -0.698 -0.9204 1495832 CBMicro_031760 Fc1cccc(Cl)c1COc2ccc3c4CCCCc4c(=O)oc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D23 positive control 0.086 -0.247 -20.54 0.084 -0.253 -22.42 -30.3746 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 D24 positive control 0.086 -0.247 -20.54 0.09 -0.247 -21.88 -29.9986 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E01 mock treatment 0.324 -0.00942 -0.78 0.327 -0.00994 -0.88 -1.1756 -0.9982 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E02 mock treatment 0.339 0.00558 0.46 0.336 -9.35E-4 -0.08 0.269 0.5715 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E03 compound treatment 0.334 5.81E-4 0.05 0.336 -9.35E-4 -0.08 -0.0245 -0.2559 1941468 CBMicro_031761 Cc1ccc(OCCOc2ccc(/C=N/n3cnnc3)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E04 compound treatment 0.361 0.0276 2.29 0.362 0.0251 2.22 3.1897 0.9999 1941469 CBMicro_031762 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E05 compound treatment 0.329 -0.00442 -0.37 0.333 -0.00394 -0.35 -0.506 -0.9997 1941470 CBMicro_031763 CC(C)NC(=O)CN(c1ccc(C)c(Cl)c1)S(=O)(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E06 compound treatment 0.327 -0.00642 -0.53 0.325 -0.0119 -1.06 -1.1248 -0.9496 1941471 CBMicro_031764 Clc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccc(Br)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E07 compound treatment 0.355 0.0216 1.79 0.35 0.0131 1.16 2.0855 0.9777 1941472 CBMicro_031765 CCOc1cccc(c1)N2C(=O)CC(S/C(=N/c3ccccc3)/NCc4ccc(OC)cc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E08 compound treatment 0.338 0.00458 0.38 0.336 -9.35E-4 -0.08 0.2103 0.5403 1941473 CBMicro_031766 C/C(=C\c1ccccc1)/C=N/NC(=O)c2cc(n[nH]2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E09 compound treatment 0.365 0.0316 2.62 0.376 0.0391 3.46 4.3019 0.9906 1941474 CBMicro_031767 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(cc3)[N+](=O)[O-])C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E10 compound treatment 0.346 0.0126 1.04 0.354 0.0171 1.51 1.8079 0.9837 1543342 CBMicro_031768 COc1cc(NC(=O)COc2cc(C)ccc2C(C)(C)C)c(OC)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E11 compound treatment 0.329 -0.00442 -0.37 0.333 -0.00394 -0.35 -0.506 -0.9997 1941475 CBMicro_031769 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cccc(C)c3C)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E12 compound treatment 0.316 -0.0174 -1.45 0.323 -0.0139 -1.23 -1.8958 -0.9969 1615683 CBMicro_031770 Clc1cccc(c1)C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E13 compound treatment 0.316 -0.0174 -1.45 0.339 0.00206 0.18 -0.8932 -0.6128 1941476 CBMicro_031771 COc1sc(SC)cc1/C=N/NC(=O)C(NC(=O)c2ccccc2)c3n[nH]c(=O)c4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E14 compound treatment 0.304 -0.0294 -2.44 0.312 -0.0249 -2.21 -3.2896 -0.9988 1211147 CBMicro_031772 CCOc1cccc(c1)N2C(=O)CC(SCC(=O)Nc3ccc4ccccc4c3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E15 compound treatment 0.364 0.0306 2.54 0.379 0.0421 3.73 4.4312 0.9825 1941477 CBMicro_031773 CCOc1ccccc1C(=O)N/N=C/c2cn(nc2c3ccc(OC)cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E16 compound treatment 0.408 0.0746 6.19 0.403 0.0661 5.85 8.5181 0.9996 1941478 CBMicro_031774 OS(=O)(=O)CCCn1cnc2ncc3CCC/C(=C\c4ccccc4)/c3[n+]12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E17 compound treatment 0.355 0.0216 1.79 0.367 0.0301 2.66 3.1509 0.9814 1210747 CBMicro_031775 CCC(=O)c1ccc(OCC(O)COc2ccc(cc2OC)C(=O)CC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E18 compound treatment 0.352 0.0186 1.54 0.353 0.0161 1.42 2.0974 0.9992 1941479 CBMicro_031776 Brc1ccc(NC=C2C(=O)CC(CC2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E19 compound treatment 0.335 0.00158 0.13 0.333 -0.00394 -0.35 -0.1538 -0.4128 1539883 CBMicro_031777 OC(=O)c1ccc(Cl)cc1NC(=O)CN2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E20 compound treatment 0.349 0.0156 1.29 0.346 0.00906 0.8 1.4827 0.9737 1941480 CBMicro_031778 COc1ccccc1NCC(=O)N/N=C/c2cc(Br)cs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E21 compound treatment 0.356 0.0226 1.87 0.356 0.0191 1.69 2.5202 0.9987 1941481 CBMicro_031779 [O-][N+](=O)c1ccc2C(=O)N(CC(=O)Nc3ccc4ccccc4c3)C(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E22 compound treatment 0.195 -0.138 -11.49 0.228 -0.109 -9.65 -14.9521 -0.9962 1941482 CBMicro_031780 OC(=O)c1cc(NN=C(C#N)C#N)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E23 positive control 0.083 -0.25 -20.79 0.084 -0.253 -22.42 -30.5507 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 E24 positive control 0.087 -0.246 -20.46 0.094 -0.243 -21.53 -29.6892 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F01 mock treatment 0.326 -0.00742 -0.62 0.331 -0.00594 -0.53 -0.8075 -0.9969 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F02 mock treatment 0.333 -4.19E-4 -0.03 0.335 -0.00194 -0.17 -0.1459 -0.8336 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F03 compound treatment 0.33 -0.00342 -0.28 0.337 6.45E-5 0.01 -0.1967 -0.6927 1354278 CBMicro_031781 Brc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F04 compound treatment 0.34 0.00658 0.55 0.33 -0.00694 -0.61 -0.0483 -0.0587 1585026 CBMicro_031782 Clc1cccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F05 compound treatment 0.331 -0.00242 -0.2 0.336 -9.35E-4 -0.08 -0.2006 -0.9234 1941483 CBMicro_031783 O=C(/C=C/c1ccco1)N2CCN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F06 compound treatment 0.327 -0.00642 -0.53 0.336 -9.35E-4 -0.08 -0.4355 -0.8074 1733788 CBMicro_031784 CCc1cc2c(cc(=O)oc2cc1OC(=O)C)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F07 compound treatment 0.33 -0.00342 -0.28 0.325 -0.0119 -1.06 -0.9487 -0.8662 1293542 CBMicro_031785 Cc1nc(NC(=O)C2C(C3CCC2O3)C(=O)O)sc1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F08 compound treatment 0.347 0.0136 1.13 0.343 0.00606 0.54 1.1773 0.9426 1941484 CBMicro_031786 CCCOc1ccc(N/C=C/C(=O)c2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F09 compound treatment 0.345 0.0116 0.96 0.333 -0.00394 -0.35 0.4332 0.4236 1941485 CBMicro_031787 COc1ccc(cc1)S(=O)(=O)N/N=C/c2cc3OCOc3cc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F10 compound treatment 0.366 0.0326 2.7 0.36 0.0231 2.04 3.3579 0.9905 1349796 CBMicro_031788 CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc2ccc(I)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F11 compound treatment 0.355 0.0216 1.79 0.345 0.00806 0.71 1.7722 0.9188 1941486 CBMicro_031789 C/C(=N\NC(=O)C1(C)CC1(Br)Br)/c2ccc(Cl)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F12 compound treatment 0.332 -0.00142 -0.12 0.334 -0.00294 -0.26 -0.2673 -0.9359 1230164 CBMicro_031790 Cc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)N4CCCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F13 compound treatment 0.345 0.0116 0.96 0.341 0.00406 0.36 0.9345 0.9102 1206796 CBMicro_031791 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccc(Br)cc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F14 compound treatment 0.332 -0.00142 -0.12 0.321 -0.0159 -1.41 -1.0819 -0.7635 1310990 CBMicro_031792 Cc1onc(c1C(=O)NCCc2nc3ccccc3[nH]2)c4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F15 compound treatment 0.337 0.00358 0.3 0.336 -9.35E-4 -0.08 0.1516 0.4912 1941487 CBMicro_031793 O=C(CCCOc1ccccc1)NCCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F16 compound treatment 0.362 0.0286 2.37 0.358 0.0211 1.87 2.9978 0.993 1229707 CBMicro_031794 CCOC(=O)c1c(NC(=O)C2CC=CCC2C(=O)O)scc1c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F17 compound treatment 0.377 0.0436 3.62 0.358 0.0211 1.87 3.8783 0.9526 1631200 CBMicro_031795 O=C1CCCCC1Oc2ccc3c(cc(=O)oc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F18 compound treatment 0.338 0.00458 0.38 0.325 -0.0119 -1.06 -0.479 -0.4262 1357325 CBMicro_031796 CC1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F19 compound treatment 0.385 0.0516 4.28 0.389 0.0521 4.61 6.2906 0.9993 1941488 CBMicro_031797 COc1ccc2/C(=N/OC(=O)c3ccc(Oc4ccccc4)cc3)/CCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F20 compound treatment 0.354 0.0206 1.71 0.355 0.0181 1.6 2.3402 0.9995 1558586 CBMicro_031798 COc1cc2oc(=O)c3CCCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F21 compound treatment 0.39 0.0566 4.7 0.378 0.0411 3.64 5.8948 0.992 1411993 CBMicro_031799 CCOC(=O)C1=C(NC(=O)CC)Oc2ccc3ccccc3c2C1c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F22 compound treatment 0.343 0.00958 0.8 0.34 0.00306 0.27 0.7545 0.8977 1441192 CBMicro_031800 CC(=O)Oc1ccc(cc1)c2cccc(c2)C(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F23 positive control 0.084 -0.249 -20.71 0.086 -0.251 -22.24 -30.3666 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 F24 positive control 0.087 -0.246 -20.46 0.091 -0.246 -21.8 -29.8772 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G01 mock treatment 0.321 -0.0124 -1.03 0.331 -0.00594 -0.53 -1.101 -0.9512 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G02 mock treatment 0.329 -0.00442 -0.37 0.333 -0.00394 -0.35 -0.506 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G03 compound treatment 0.321 -0.0124 -1.03 0.322 -0.0149 -1.32 -1.665 -0.9924 1941489 CBMicro_031801 CN1C(=O)/C(=C\c2cccc(OS(=O)(=O)c3ccc(C)cc3)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G04 compound treatment 0.327 -0.00642 -0.53 0.335 -0.00194 -0.17 -0.4981 -0.8897 1941490 CBMicro_031802 CC(C)NC=C1C(=O)CC(CC1=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G05 compound treatment 0.315 -0.0184 -1.53 0.317 -0.0199 -1.77 -2.3305 -0.9974 1563312 CBMicro_031803 O=C1CC(Nc2ccccc2)C(=O)N1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G06 compound treatment 0.324 -0.00942 -0.78 0.324 -0.0129 -1.15 -1.3636 -0.9826 1177887 CBMicro_031804 OC(=O)c1cc(O)ccc1NC(=O)CN2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G07 compound treatment 0.326 -0.00742 -0.62 0.327 -0.00994 -0.88 -1.0581 -0.9847 1941491 CBMicro_031805 COc1ccc(/C=C/C(=O)Nc2ccccc2F)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G08 compound treatment 0.312 -0.0214 -1.78 0.316 -0.0209 -1.86 -2.5693 -0.9998 1941492 CBMicro_031806 CC(=O)C1=C(C)NC(=S)NC1c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G09 compound treatment 0.37 0.0366 3.04 0.377 0.0401 3.55 4.6581 0.997 1941493 CBMicro_031807 COC(C(=O)N/N=C/c1cn(nc1c2ccccc2)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G10 compound treatment 0.338 0.00458 0.38 0.332 -0.00494 -0.44 -0.0404 -0.0697 1941494 CBMicro_031808 COCCOC(=O)c1ccc(NC(=O)c2c(C)onc2c3ccccc3Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G11 compound treatment 0.313 -0.0204 -1.7 0.325 -0.0119 -1.06 -1.9466 -0.9742 1941495 CBMicro_031809 Cc1nn(C(=O)c2ccco2)c(C)c1Sc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G12 compound treatment 0.323 -0.0104 -0.87 0.329 -0.00794 -0.7 -1.1089 -0.9947 1154509 CBMicro_031810 Cc1ccc(cc1NC(=O)CCC(=O)O)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G13 compound treatment 0.367 0.0336 2.79 0.371 0.0341 3.02 4.106 0.9992 1354500 CBMicro_031811 Fc1cccc(c1)C(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G14 compound treatment 0.333 -4.19E-4 -0.03 0.345 0.00806 0.71 0.4807 0.6719 1941496 CBMicro_031812 Brc1ccc(/C=N/N2C(=O)CSC2=S)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G15 compound treatment 0.308 -0.0254 -2.11 0.319 -0.0179 -1.59 -2.6161 -0.9902 1941497 CBMicro_031813 CC1=C(C(NC(=S)N1)c2ccc(C)cc2)C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G16 compound treatment 0.506 0.173 14.33 0.499 0.162 14.36 20.2868 1.0 1941498 CBMicro_031814 CCOc1ccccc1/C=C\2/SC(=S)N(NC(=O)c3ccccc3C)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G17 compound treatment 0.333 -4.19E-4 -0.03 0.336 -9.35E-4 -0.08 -0.0832 -0.9257 1462252 CBMicro_031815 Fc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3ccc(Br)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G18 compound treatment 0.335 0.00158 0.13 0.331 -0.00594 -0.53 -0.2792 -0.5149 1505137 CBMicro_031816 O=C1CCC(=O)N1c2cccc(c2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G19 compound treatment 0.377 0.0436 3.62 0.381 0.0441 3.91 5.3196 0.9993 1941499 CBMicro_031817 CN1CCN(CC1)C2=NC(=O)/C(=C/c3ccc(cc3)[N+](=O)[O-])/S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G20 compound treatment 0.34 0.00658 0.55 0.342 0.00506 0.45 0.7037 0.9952 1941500 CBMicro_031818 COc1cc(NC=C2C(=O)N(C)C(=O)N(C)C2=O)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G21 compound treatment 0.328 -0.00542 -0.45 0.33 -0.00694 -0.61 -0.7527 -0.9882 1674291 CBMicro_031819 OC(=O)CCn1c(=O)c2cc3c(=O)n(CCC(=O)O)c(=O)c3cc2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G22 compound treatment 0.324 -0.00942 -0.78 0.322 -0.0149 -1.32 -1.4889 -0.9685 1941501 CBMicro_031820 Cc1cccc(N2C(=O)/C(=C/c3cccc(F)c3)/SC2=S)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G23 positive control 0.085 -0.248 -20.62 0.085 -0.252 -22.33 -30.3706 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 G24 positive control 0.09 -0.243 -20.21 0.093 -0.244 -21.62 -29.5758 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H01 mock treatment 0.324 -0.00942 -0.78 0.331 -0.00594 -0.53 -0.9249 -0.9814 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H02 mock treatment 0.331 -0.00242 -0.2 0.329 -0.00794 -0.7 -0.6393 -0.8741 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H03 compound treatment 0.328 -0.00542 -0.45 0.334 -0.00294 -0.26 -0.5021 -0.9661 1941502 CBMicro_031821 CC(Oc1ccc2c3CCCCc3c(=O)oc2c1)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H04 compound treatment 0.322 -0.0114 -0.95 0.325 -0.0119 -1.06 -1.4183 -0.9985 1941503 CBMicro_031822 COC(=O)Cn1cnc2ccccc2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H05 compound treatment 0.333 -4.19E-4 -0.03 0.335 -0.00194 -0.17 -0.1459 -0.8336 1323582 CBMicro_031823 COc1ccc(NC(=O)c2ccc3ccccc3n2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H06 compound treatment 0.326 -0.00742 -0.62 0.329 -0.00794 -0.7 -0.9328 -0.9978 1941504 CBMicro_031824 Clc1ccc(OC(=O)CCc2ccccc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H07 compound treatment 0.244 -0.0894 -7.42 0.258 -0.0789 -7.0 -10.1957 -0.9996 1941505 CBMicro_031825 Oc1cc(O)cc(c1)C(=O)N/N=C/c2coc3ccccc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H08 compound treatment 0.32 -0.0134 -1.11 0.332 -0.00494 -0.44 -1.097 -0.9166 1941506 CBMicro_031826 FC(F)(F)c1ccccc1N/C=C/C(=O)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H09 compound treatment 0.335 0.00158 0.13 0.339 0.00206 0.18 0.2222 0.9867 1239417 CBMicro_031827 CCCc1cc(C(=O)OC)c(NC(=O)C2C(C3CCC2C3)C(=O)O)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H10 compound treatment 0.357 0.0236 1.96 0.34 0.00306 0.27 1.5763 0.7976 1716798 CBMicro_031828 CCOc1ccc(NC(=O)C2CC2(c3cccc(OC)c3)c4cccc(OC)c4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H11 compound treatment 0.292 -0.0414 -3.44 0.309 -0.0279 -2.48 -4.182 -0.987 1941507 CBMicro_031829 COc1ccccc1OCCn2cc(/C=C\3/SC(=S)N(Cc4ccccc4)C3=O)c5ccccc25 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H12 compound treatment 0.327 -0.00642 -0.53 0.326 -0.0109 -0.97 -1.0621 -0.9603 1522581 CBMicro_031830 COc1ccccc1C(=O)Nc2ccc(cc2)C(=O)OC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H13 compound treatment 0.316 -0.0174 -1.45 0.328 -0.00894 -0.79 -1.5825 -0.9598 1941508 CBMicro_031831 [O-][N+](=O)c1cccc(c1)C2N3CCCN23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H14 compound treatment 0.364 0.0306 2.54 0.351 0.0141 1.25 2.6765 0.9464 1454236 CBMicro_031832 CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc2ccccc2F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H15 compound treatment 0.317 -0.0164 -1.36 0.322 -0.0149 -1.32 -1.8998 -0.9999 1550325 CBMicro_031833 CCC1=NN(C(=O)COc2ccccc2)C(O)(C1)c3ccncc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H16 compound treatment 0.358 0.0246 2.04 0.369 0.0321 2.84 3.4523 0.9868 1184996 CBMicro_031834 O=C(NCCc1ccccc1)C2C(=C2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H17 compound treatment 0.348 0.0146 1.21 0.349 0.0121 1.07 1.612 0.9981 1663481 CBMicro_031835 CCOc1ccc2c3CCCCc3c(=O)oc2c1OCC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H18 compound treatment 0.335 0.00158 0.13 0.334 -0.00294 -0.26 -0.0912 -0.3129 1941509 CBMicro_031836 CN1C(=O)/C(=C/2\SC(=O)NC2=O)/c3cc(Br)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H19 compound treatment 0.367 0.0336 2.79 0.364 0.0271 2.4 3.6673 0.9972 1941510 CBMicro_031837 COc1ccc(cc1OC)C(=O)O/N=C/2\CCCc3cc(OC)c(C)cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H20 compound treatment 0.339 0.00558 0.46 0.351 0.0141 1.25 1.209 0.9092 1941511 CBMicro_031838 CCCCOc1ccc2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H21 compound treatment 0.358 0.0246 2.04 0.344 0.00706 0.63 1.8857 0.8834 1941512 CBMicro_031839 COC(=O)c1cccc(NC(=O)/C=C/c2ccc(OC)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H22 compound treatment 0.335 0.00158 0.13 0.341 0.00406 0.36 0.3475 0.9064 1162649 CBMicro_031840 Oc1cc2oc(=O)c3CCCCc3c2cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H23 positive control 0.085 -0.248 -20.62 0.087 -0.25 -22.15 -30.2453 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 H24 positive control 0.09 -0.243 -20.21 0.094 -0.243 -21.53 -29.5131 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I01 mock treatment 0.332 -0.00142 -0.12 0.344 0.00706 0.63 0.3594 0.5641 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I02 mock treatment 0.338 0.00458 0.38 0.344 0.00706 0.63 0.7116 0.9714 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I03 compound treatment 0.336 0.00258 0.21 0.339 0.00206 0.18 0.2809 0.9969 1941513 CBMicro_031841 COc1cccc(c1)N(CC(=O)NCC=C)S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I04 compound treatment 0.334 5.81E-4 0.05 0.331 -0.00594 -0.53 -0.3379 -0.6396 1941514 CBMicro_031842 [O-][N+](=O)c1ccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)c5nc6ccccc6o5)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I05 compound treatment 0.354 0.0206 1.71 0.343 0.00606 0.54 1.5882 0.8867 1941515 CBMicro_031843 [O-][N+](=O)c1ccccc1c2ccc(/C=N/NC(=O)COc3ccccc3Cl)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I06 compound treatment 0.322 -0.0114 -0.95 0.321 -0.0159 -1.41 -1.669 -0.9812 1611650 CBMicro_031844 CCOc1cc(ccc1O)C2NC(=S)NC(=C2C(=O)Nc3ccc(OC)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I07 compound treatment 0.325 -0.00842 -0.7 0.316 -0.0209 -1.86 -1.8062 -0.911 1941516 CBMicro_031845 Cc1occc1C(=O)N/N=C/c2ccc(o2)c3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I08 compound treatment 0.328 -0.00542 -0.45 0.322 -0.0149 -1.32 -1.2541 -0.8971 1307030 CBMicro_031846 CCC(=O)N(CCc1ccccc1)C2CC(=O)N(C2=O)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I09 compound treatment 0.291 -0.0424 -3.52 0.318 -0.0189 -1.68 -3.6767 -0.9425 1941517 CBMicro_031847 Brc1ccccc1/C=N/NC(=O)CSc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I10 compound treatment 0.502 0.169 14.0 0.501 0.164 14.54 20.1774 0.9998 1941518 CBMicro_031848 Oc1ccc(cc1)N2C(=O)/C(=C/c3ccc(O)c(O)c3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I11 compound treatment 0.325 -0.00842 -0.7 0.3 -0.0369 -3.27 -2.8088 -0.8392 1941519 CBMicro_031849 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I12 compound treatment 0.336 0.00258 0.21 0.353 0.0161 1.42 1.1582 0.8045 1424769 CBMicro_031850 CN(C)S(=O)(=O)c1cc(c2cccc3C(=O)Nc1c32)S(=O)(=O)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I13 compound treatment 0.4 0.0666 5.53 0.442 0.105 9.31 10.4924 0.969 1941520 CBMicro_031851 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\NCc3ccc(Cl)cc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I14 compound treatment 0.374 0.0406 3.37 0.359 0.0221 1.96 3.7649 0.9665 1941521 CBMicro_031852 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\N(C)C)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I15 compound treatment 0.329 -0.00442 -0.37 0.327 -0.00994 -0.88 -0.882 -0.9247 1164309 CBMicro_031853 CN1CCN(CC1)NC(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I16 compound treatment 1.076 0.743 61.65 0.987 0.65 57.61 84.3283 0.9994 1941522 CBMicro_031854 CC(C)C(N1C(=O)/C(=C/C(=C/c2ccccc2)/C)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I17 compound treatment 0.347 0.0136 1.13 0.355 0.0181 1.6 1.9292 0.9853 1941523 CBMicro_031855 Brc1ccc(/C=N/Nc2nncc(=O)[nH]2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I18 compound treatment 0.328 -0.00542 -0.45 0.335 -0.00194 -0.17 -0.4394 -0.9126 1941524 CBMicro_031856 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I19 compound treatment 0.362 0.0286 2.37 0.352 0.0151 1.34 2.6218 0.963 1781928 CBMicro_031857 CN1C(=C(C(NC1=O)c2ccccc2[N+](=O)[O-])C(=O)OCCc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I20 compound treatment 0.38 0.0466 3.87 0.364 0.0271 2.4 4.4304 0.9736 1705854 CBMicro_031858 Cc1ccc2oc(nc2c1)c3cc(NC(=O)c4ccc(cc4)C(C)(C)C)ccc3O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I21 compound treatment 0.402 0.0686 5.69 0.403 0.0661 5.85 8.1658 0.9999 1941525 CBMicro_031859 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\NCCc3ccccc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I22 compound treatment 0.333 -4.19E-4 -0.03 0.334 -0.00294 -0.26 -0.2086 -0.7947 1941526 CBMicro_031860 C/C(=N\NC(=O)c1cc(n[nH]1)c2ccccc2)/c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I23 positive control 0.084 -0.249 -20.71 0.097 -0.24 -21.26 -29.6773 -0.9999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 I24 positive control 0.089 -0.244 -20.29 0.096 -0.241 -21.35 -29.4465 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J01 mock treatment 0.295 -0.0384 -3.19 0.311 -0.0259 -2.3 -3.8806 -0.9871 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J02 mock treatment 0.341 0.00758 0.63 0.346 0.00906 0.8 1.013 0.9927 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J03 compound treatment 0.3 -0.0334 -2.77 0.316 -0.0209 -1.86 -3.2737 -0.9809 1184489 CBMicro_031861 Cc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J04 compound treatment 0.338 0.00458 0.38 0.334 -0.00294 -0.26 0.0849 0.1844 1650460 CBMicro_031862 Clc1ccccc1OCC(=O)NCCc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J05 compound treatment 0.332 -0.00142 -0.12 0.336 -9.35E-4 -0.08 -0.1419 -0.9852 1238684 CBMicro_031863 OC(=O)c1cccc(NC(=O)c2ccc3ccccc3n2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J06 compound treatment 0.309 -0.0244 -2.03 0.235 -0.102 -9.03 -7.8213 -0.8448 1941527 CBMicro_031864 CC(C)(C)c1ccc(cc1)C(=O)Oc2ccc(/C=N/O)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J07 compound treatment 0.322 -0.0114 -0.95 0.324 -0.0129 -1.15 -1.481 -0.9955 1941528 CBMicro_031865 Cc1ccc(/C=N/NC(=O)C2(C)CC2(Br)Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J08 compound treatment 0.322 -0.0114 -0.95 0.333 -0.00394 -0.35 -0.917 -0.9078 1941529 CBMicro_031866 O=C(CC1CCCCC1)NCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J09 compound treatment 0.342 0.00858 0.71 0.337 6.45E-5 0.01 0.5078 0.7128 1475546 CBMicro_031867 CCC1CCc2c(C(=O)N)c(NC(=O)C3C(C4CCC3C4)C(=O)O)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J10 compound treatment 0.326 -0.00742 -0.62 0.338 0.00106 0.09 -0.3688 -0.5919 1941530 CBMicro_031868 COc1ccc(OC)c(/C=C/C(=O)NCC2CCCO2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J11 compound treatment 0.343 0.00958 0.8 0.342 0.00506 0.45 0.8798 0.9633 1145273 CBMicro_031869 Cc1c(Cl)cccc1NC(=O)C2C(=C2c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J12 compound treatment 0.369 0.0356 2.95 0.373 0.0361 3.2 4.3487 0.9992 1567679 CBMicro_031870 COc1ccc(cc1)c2cc(=O)oc3cc(O)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J13 compound treatment 0.312 -0.0214 -1.78 0.316 -0.0209 -1.86 -2.5693 -0.9998 1137633 CBMicro_031871 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J14 compound treatment 0.334 5.81E-4 0.05 0.328 -0.00894 -0.79 -0.5259 -0.6628 1408285 CBMicro_031872 C1CCC(CC1)Nc2nc(nc3ccccc23)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J15 compound treatment 0.326 -0.00742 -0.62 0.344 0.00706 0.63 0.0072 0.0082 1941531 CBMicro_031873 Cc1cccc(NC(=O)CC2CCCCC2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J16 compound treatment 0.362 0.0286 2.37 0.359 0.0221 1.96 3.0605 0.9954 1143012 CBMicro_031874 Clc1ccc(NC(=O)C2C3CCCCC=CC23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J17 compound treatment 0.389 0.0556 4.61 0.379 0.0421 3.73 5.8987 0.9944 1526256 CBMicro_031875 O=C(Nc1nc2ccccc2n1CCOc3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J18 compound treatment 0.456 0.123 10.18 0.427 0.0901 7.98 12.8398 0.9928 1309186 CBMicro_031876 CC1=NN(C(=O)c2ccncc2)C(O)(C1)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J19 compound treatment 0.383 0.0496 4.12 0.382 0.0451 3.99 5.7345 0.9999 1941532 CBMicro_031877 COc1cc(/C=C\2/C=C(OC2=O)c3ccccc3)ccc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J20 compound treatment 0.317 -0.0164 -1.36 0.344 0.00706 0.63 -0.5212 -0.3474 1542101 CBMicro_031878 CCOC(=O)c1c(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCCC3)sc4CCCc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J21 compound treatment 0.329 -0.00442 -0.37 0.337 6.45E-5 0.01 -0.2554 -0.696 1719259 CBMicro_031879 NC(=O)C1CCN(CC1)C(=O)c2ccccc2NC(=O)c3ccccc3Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J22 compound treatment 0.336 0.00258 0.21 0.335 -0.00194 -0.17 0.0302 0.1101 1941533 CBMicro_031880 [O-][N+](=O)c1cc(ccc1Oc2ccc3c4CCCCc4c(=O)oc3c2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J23 positive control 0.084 -0.249 -20.71 0.091 -0.246 -21.8 -30.0533 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 J24 positive control 0.089 -0.244 -20.29 0.093 -0.244 -21.62 -29.6345 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K01 mock treatment 0.33 -0.00342 -0.28 0.341 0.00406 0.36 0.054 0.1177 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K02 mock treatment 0.332 -0.00142 -0.12 0.338 0.00106 0.09 -0.0166 -0.1101 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K03 compound treatment 0.329 -0.00442 -0.37 0.33 -0.00694 -0.61 -0.694 -0.9696 1941534 CBMicro_031881 CN1C(=O)/C(=C\c2cccc(OCc3ccc(Cl)cc3Cl)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K04 compound treatment 0.321 -0.0124 -1.03 0.318 -0.0189 -1.68 -1.9157 -0.9726 1941535 CBMicro_031882 Cc1ccccc1/[N+](=C/c2cccs2)/[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K05 compound treatment 0.34 0.00658 0.55 0.34 0.00306 0.27 0.5783 0.948 1181805 CBMicro_031883 CC(=O)N1CCN(CC1)C(CNS(=O)(=O)c2ccc(C)cc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K06 compound treatment 0.34 0.00658 0.55 0.331 -0.00594 -0.53 0.0144 0.0189 1404656 CBMicro_031884 OC(=O)c1ccccc1NC(=O)c2cccc(c2)N3C(=O)c4ccccc4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K07 compound treatment 0.344 0.0106 0.88 0.335 -0.00194 -0.17 0.4998 0.5585 1941536 CBMicro_031885 Brc1ccc(cc1)c2ccc(o2)C(=S)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K08 compound treatment 0.334 5.81E-4 0.05 0.324 -0.0129 -1.15 -0.7765 -0.6768 1941537 CBMicro_031886 CN1C(=O)N(C)C(=O)C(=CNCCN2CCN(CC2)C(=O)c3ccccc3)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K09 compound treatment 0.318 -0.0154 -1.28 0.323 -0.0139 -1.23 -1.7784 -0.9998 1136050 CBMicro_031887 CC(=O)Oc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K10 compound treatment 0.332 -0.00142 -0.12 0.326 -0.0109 -0.97 -0.7686 -0.7873 1941538 CBMicro_031888 CC(C)NC(=O)N(C)C/1CCCC\C1=C/C(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K11 compound treatment 0.348 0.0146 1.21 0.347 0.0101 0.89 1.4866 0.9887 1233884 CBMicro_031889 Cc1cc(NC(=O)c2cccc3ccccc23)ccc1NC(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K12 compound treatment 0.317 -0.0164 -1.36 0.322 -0.0149 -1.32 -1.8998 -0.9999 1650227 CBMicro_031890 CCOc1cccc(c1)N2C(=O)CC(SCC(=O)Nc3ccc(Cl)cc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K13 compound treatment 0.346 0.0126 1.04 0.339 0.00206 0.18 0.8679 0.8185 1436545 CBMicro_031891 CN1CCc2c(C(=O)OC(C)(C)C)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K14 compound treatment 0.327 -0.00642 -0.53 0.331 -0.00594 -0.53 -0.7488 -1.0 1320069 CBMicro_031892 Clc1ccc(cc1Cl)c2nc3ccccc3c(=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K15 compound treatment 0.381 0.0476 3.95 0.397 0.0601 5.32 6.5571 0.9892 1223829 CBMicro_031893 CCCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K16 compound treatment 0.396 0.0626 5.2 0.403 0.0661 5.85 7.8136 0.9982 1218409 CBMicro_031894 CCOc1ccc(cc1)c2nc3cc(NC(=O)c4ccccc4F)ccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K17 compound treatment 0.335 0.00158 0.13 0.341 0.00406 0.36 0.3475 0.9064 1350854 CBMicro_031895 OC(=O)CCC(=O)Nc1ccc(Cc2ccc(NC(=O)CCC(=O)O)c(O)c2)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K18 compound treatment 0.538 0.205 16.98 0.547 0.21 18.62 25.1733 0.999 1941539 CBMicro_031896 COc1ccccc1/C=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K19 compound treatment 0.566 0.233 19.31 0.594 0.257 22.78 29.7622 0.9966 1941540 CBMicro_031897 NC(=O)/C(=C/c1ccc(o1)c2ccc(cc2)S(=O)(=O)N)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K20 compound treatment 0.355 0.0216 1.79 0.342 0.00506 0.45 1.5842 0.8577 1941541 CBMicro_031898 Cc1ccc(cc1)C(=O)NNC(=O)COc2ccc(cc2)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K21 compound treatment 0.307 -0.0264 -2.19 0.305 -0.0319 -2.83 -3.5521 -0.9921 1941542 CBMicro_031899 CC(=O)c1ccc(NC(=O)Nc2ccccc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K22 compound treatment 0.338 0.00458 0.38 0.335 -0.00194 -0.17 0.1476 0.3538 1941543 CBMicro_031900 COCCOC(=O)c1ccc(NC(=O)c2ccc(OC)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K23 positive control 0.086 -0.247 -20.54 0.087 -0.25 -22.15 -30.1866 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 K24 positive control 0.092 -0.241 -20.04 0.094 -0.243 -21.53 -29.3957 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L01 mock treatment 0.335 0.00158 0.13 0.335 -0.00194 -0.17 -0.0285 -0.132 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L02 mock treatment 0.334 5.81E-4 0.05 0.337 6.45E-5 0.01 0.0381 0.7855 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L03 compound treatment 0.309 -0.0244 -2.03 0.317 -0.0199 -1.77 -2.6828 -0.9977 1328351 CBMicro_031901 O=C(COc1ccc2c3CCCCc3c(=O)oc2c1)OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L04 compound treatment 0.312 -0.0214 -1.78 0.335 -0.00194 -0.17 -1.3787 -0.7717 1299041 CBMicro_031902 CCOC(=O)C(Oc1ccc2c3ccccc3c(=O)oc2c1C)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L05 compound treatment 0.344 0.0106 0.88 0.354 0.0171 1.51 1.6905 0.9666 1941544 CBMicro_031903 Cc1sc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])nc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L06 compound treatment 0.358 0.0246 2.04 0.347 0.0101 0.89 2.0737 0.9311 1181517 CBMicro_031904 COc1ccc(CCNC(=O)C2CC2(c3cccc(C)c3)c4cccc(C)c4)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L07 compound treatment 0.325 -0.00842 -0.7 0.321 -0.0159 -1.41 -1.4928 -0.9474 1941545 CBMicro_031905 CC(=O)NC(NC(=S)N1CCCCCC1)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L08 compound treatment 0.33 -0.00342 -0.28 0.334 -0.00294 -0.26 -0.3847 -0.9991 1941546 CBMicro_031906 COc1ccc(CCNC(=O)/C=C/c2cc(OC)ccc2OC)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L09 compound treatment 0.315 -0.0184 -1.53 0.324 -0.0129 -1.15 -1.8919 -0.9899 1343912 CBMicro_031907 Cc1ccc(C)c(c1)c2cc(C(=O)NN)c3ccccc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L10 compound treatment 0.316 -0.0174 -1.45 0.322 -0.0149 -1.32 -1.9585 -0.999 1354704 CBMicro_031908 CC(=O)Oc1cc(C)cc2oc(=O)c(Cc3ccccc3)c(C)c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L11 compound treatment 0.33 -0.00342 -0.28 0.329 -0.00794 -0.7 -0.698 -0.9204 1941547 CBMicro_031909 Clc1ccc(cc1)C2N(C(=O)N3CCCN23)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L12 compound treatment 0.314 -0.0194 -1.61 0.317 -0.0199 -1.77 -2.3892 -0.999 1941548 CBMicro_031910 COCCNc1nc(nc2ccccc12)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L13 compound treatment 0.331 -0.00242 -0.2 0.327 -0.00994 -0.88 -0.7646 -0.8467 1240652 CBMicro_031911 CCCCc1cc(=O)oc2cc(OC(=O)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L14 compound treatment 0.349 0.0156 1.29 0.335 -0.00194 -0.17 0.7933 0.608 1141931 CBMicro_031912 Clc1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L15 compound treatment 0.373 0.0396 3.29 0.367 0.0301 2.66 4.2075 0.9946 1941549 CBMicro_031913 COc1ccc(cc1OC)C(=O)O/N=C/2\CCCc3c(C)c(O)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L16 compound treatment 0.333 -4.19E-4 -0.03 0.332 -0.00494 -0.44 -0.3339 -0.761 1718695 CBMicro_031914 CCCc1cc(=O)oc2c(C)c(OC(=O)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L17 compound treatment 0.319 -0.0144 -1.2 0.324 -0.0129 -1.15 -1.6571 -0.9998 1941550 CBMicro_031915 OC(c1ccnn1c2ccccc2)(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L18 compound treatment 0.323 -0.0104 -0.87 0.317 -0.0199 -1.77 -1.8609 -0.946 1941551 CBMicro_031916 CCc1ccc(CN/C=C/C(=O)c2ccc(Br)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L19 compound treatment 0.433 0.0996 8.27 0.401 0.0641 5.68 9.8603 0.9832 1941552 CBMicro_031917 Cc1ccc(C2=C/C(=C/c3ccccn3)/C(=O)O2)c(C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L20 compound treatment 0.332 -0.00142 -0.12 0.34 0.00306 0.27 0.1087 0.3672 1734233 CBMicro_031918 Cc1c(OCC(=O)O)ccc2c3CCCCc3c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L21 compound treatment 0.34 0.00658 0.55 0.331 -0.00594 -0.53 0.0144 0.0189 1131891 CBMicro_031919 CC1CCN(CC1)c2nc(nc3ccccc23)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L22 compound treatment 0.343 0.00958 0.8 0.363 0.0261 2.31 2.1958 0.8988 1346840 CBMicro_031920 Cc1cc(O)c2c3CCCCc3c(=O)oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L23 positive control 0.086 -0.247 -20.54 0.087 -0.25 -22.15 -30.1866 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 L24 positive control 0.09 -0.243 -20.21 0.094 -0.243 -21.53 -29.5131 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M01 mock treatment 0.331 -0.00242 -0.2 0.335 -0.00194 -0.17 -0.2633 -0.9969 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M02 mock treatment 0.333 -4.19E-4 -0.03 0.338 0.00106 0.09 0.0421 0.4186 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M03 compound treatment 0.331 -0.00242 -0.2 0.327 -0.00994 -0.88 -0.7646 -0.8467 1387162 CBMicro_031921 O=C(Nc1ccc(Cc2ccncc2)cc1)c3ccc4ccccc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M04 compound treatment 0.326 -0.00742 -0.62 0.326 -0.0109 -0.97 -1.1208 -0.9761 1941553 CBMicro_031922 Cc1cccc(C)c1OCC(=O)N/N=C/c2ccc(O)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M05 compound treatment 0.358 0.0246 2.04 0.366 0.0291 2.58 3.2643 0.9933 1169378 CBMicro_031923 Oc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1c3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M06 compound treatment 0.325 -0.00842 -0.7 0.328 -0.00894 -0.79 -1.0542 -0.9981 1941554 CBMicro_031924 CC1(C)CC(=NNC(=O)c2ccc(Br)o2)CC(C)(C)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M07 compound treatment 0.415 0.0816 6.77 0.484 0.147 13.03 14.0049 0.9535 1941555 CBMicro_031925 Clc1ccc(cc1)/C(=C/c2ccc(o2)c3cccc(Cl)c3)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M08 compound treatment 0.333 -4.19E-4 -0.03 0.332 -0.00494 -0.44 -0.3339 -0.761 1344779 CBMicro_031926 Cc1cccc2c(=O)oc(nc12)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M09 compound treatment 0.325 -0.00842 -0.7 0.331 -0.00594 -0.53 -0.8662 -0.9902 1641890 CBMicro_031927 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)COc4ccccc4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M10 compound treatment 0.347 0.0136 1.13 0.345 0.00806 0.71 1.3026 0.9758 1941556 CBMicro_031928 O=C(Cc1ccc(cc1)c2ccccc2)NNC(=O)c3ccco3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M11 compound treatment 0.327 -0.00642 -0.53 0.323 -0.0139 -1.23 -1.2501 -0.9294 1941557 CBMicro_031929 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M12 compound treatment 0.326 -0.00742 -0.62 0.33 -0.00694 -0.61 -0.8702 -1.0 1941558 CBMicro_031930 [O-][N+](=O)c1ccc(/C=N/NC(=O)CCc2n[nH]c(=O)[nH]c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M13 compound treatment 0.316 -0.0174 -1.45 0.324 -0.0129 -1.15 -1.8332 -0.9934 1941559 CBMicro_031931 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccccc3F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M14 compound treatment 0.335 0.00158 0.13 0.337 6.45E-5 0.01 0.0968 0.7372 1740285 CBMicro_031932 Cc1cccc(c1)C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M15 compound treatment 0.371 0.0376 3.12 0.368 0.0311 2.75 4.1528 0.9981 1941560 CBMicro_031933 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(C)cc3)C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M16 compound treatment 0.395 0.0616 5.11 0.385 0.0481 4.26 6.627 0.9959 1941561 CBMicro_031934 Nc1ccc(cc1)c2nc3cccc4cccc([nH]2)c43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M17 compound treatment 0.485 0.152 12.58 0.474 0.137 12.15 17.4874 0.9998 1941562 CBMicro_031935 OC(=O)CCCN1C(=O)/C(=C/c2cccc(F)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M18 compound treatment 0.406 0.0726 6.03 0.424 0.0871 7.72 9.7166 0.9925 1941563 CBMicro_031936 Brc1ccc(cc1)c2ccc(/C=C(\C#N)/C(=O)N3CCCCC3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M19 compound treatment 0.386 0.0526 4.37 0.375 0.0381 3.37 5.472 0.9919 1198874 CBMicro_031937 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccco4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M20 compound treatment 0.323 -0.0104 -0.87 0.333 -0.00394 -0.35 -0.8583 -0.9202 1698206 CBMicro_031938 Oc1ccccc1N2C(=O)c3c(C2=O)c(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M21 compound treatment 0.46 0.127 10.51 0.455 0.118 10.46 14.8292 1.0 1941564 CBMicro_031939 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3cc(F)c(F)cc3Cl)c4ncccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M22 compound treatment 0.337 0.00358 0.3 0.332 -0.00494 -0.44 -0.0991 -0.1874 1168393 CBMicro_031940 CCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M23 positive control 0.085 -0.248 -20.62 0.089 -0.248 -21.97 -30.1199 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 M24 positive control 0.092 -0.241 -20.04 0.097 -0.24 -21.26 -29.2077 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N01 mock treatment 0.339 0.00558 0.46 0.339 0.00206 0.18 0.457 0.9174 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N02 mock treatment 0.337 0.00358 0.3 0.348 0.0111 0.98 0.9036 0.8818 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N03 compound treatment 0.366 0.0326 2.7 0.378 0.0411 3.64 4.4859 0.9893 1941565 CBMicro_031941 CN(C1=C(Cl)C(=O)N(C1=O)c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N04 compound treatment 0.335 0.00158 0.13 0.334 -0.00294 -0.26 -0.0912 -0.3129 1941566 CBMicro_031942 CC(=O)COc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N05 compound treatment 0.327 -0.00642 -0.53 0.342 0.00506 0.45 -0.0595 -0.0854 1530768 CBMicro_031943 COc1ccc(c(OC)c1)c2cc(C(=O)Nc3nc(c(C)s3)c4ccccc4)c5ccccc5n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N06 compound treatment 0.416 0.0826 6.86 0.405 0.0681 6.03 9.113 0.998 1941567 CBMicro_031944 Cc1ccnc(N/C=C/C(=O)c2ccc(Br)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N07 compound treatment 0.337 0.00358 0.3 0.328 -0.00894 -0.79 -0.3497 -0.4135 1941568 CBMicro_031945 CC1(CC1(Br)Br)C(=O)N/N=C/c2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N08 compound treatment 0.341 0.00758 0.63 0.334 -0.00294 -0.26 0.2611 0.3834 1941569 CBMicro_031946 COc1ccc(NC(=O)n2nc(nc2N)C(F)(F)F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N09 compound treatment 0.345 0.0116 0.96 0.332 -0.00494 -0.44 0.3705 0.3508 1941570 CBMicro_031947 C/C(=N\NC(=O)c1ccc2OCOc2c1)/c3ccc(NC(=O)CCCC(=O)O)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N10 compound treatment 0.34 0.00658 0.55 0.336 -9.35E-4 -0.08 0.3277 0.593 1208506 CBMicro_031948 Cc1cccc(c1)C2(CC2C(=O)Nc3ccccc3F)c4cccc(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N11 compound treatment 0.346 0.0126 1.04 0.346 0.00906 0.8 1.3066 0.9916 1941571 CBMicro_031949 Clc1ccc(NC(=O)C2C(c3ccccc3)C2(Cl)Cl)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N12 compound treatment 0.324 -0.00942 -0.78 0.33 -0.00694 -0.61 -0.9876 -0.9929 1479450 CBMicro_031950 Clc1ccc(cc1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N13 compound treatment 0.353 0.0196 1.63 0.363 0.0261 2.31 2.7828 0.9852 1517098 CBMicro_031951 COc1ccc(cc1)c2cc(=O)oc3cc(OC(=O)C)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N14 compound treatment 0.326 -0.00742 -0.62 0.322 -0.0149 -1.32 -1.3715 -0.9394 1941572 CBMicro_031952 COc1cccc(c1)C2=NN(C(=O)COc3ccccc3)C(O)(C2)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N15 compound treatment 0.341 0.00758 0.63 0.329 -0.00794 -0.7 -0.0523 -0.0554 1636242 CBMicro_031953 COc1ccc2c(c1)c(=O)oc3c(C)c(OC(=O)C)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N16 compound treatment 0.345 0.0116 0.96 0.349 0.0121 1.07 1.4358 0.9986 1587013 CBMicro_031954 CCOc1ccc(NC(=O)C2CC3c4ccccc4C2c5ccccc35)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N17 compound treatment 0.353 0.0196 1.63 0.358 0.0211 1.87 2.4695 0.9976 1941573 CBMicro_031955 Cc1ccc2cccc(c2n1)S(=O)(=O)c3ccc(cc3[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N18 compound treatment 0.336 0.00258 0.21 0.334 -0.00294 -0.26 -0.0325 -0.0963 1941574 CBMicro_031956 CC(C)N/C=C/C(=O)c1ccc(Br)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N19 compound treatment 0.338 0.00458 0.38 0.337 6.45E-5 0.01 0.2729 0.7177 1941575 CBMicro_031957 COc1ccc2/C(=N/OC(=O)c3ccc(cc3)[N+](=O)[O-])/CCCc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N20 compound treatment 0.355 0.0216 1.79 0.353 0.0161 1.42 2.2735 0.9935 1419628 CBMicro_031958 O=C(N1CCN(CC1)c2ccccc2)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N21 compound treatment 0.331 -0.00242 -0.2 0.335 -0.00194 -0.17 -0.2633 -0.9969 1285521 CBMicro_031959 COc1ccc(cc1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N22 compound treatment 0.344 0.0106 0.88 0.34 0.00306 0.27 0.8132 0.8844 1722632 CBMicro_031960 Clc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N23 positive control 0.087 -0.246 -20.46 0.088 -0.249 -22.06 -30.0652 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 N24 positive control 0.091 -0.242 -20.13 0.1 -0.237 -21.0 -29.0784 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O01 mock treatment 0.337 0.00358 0.3 0.342 0.00506 0.45 0.5276 0.98 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O02 mock treatment 0.337 0.00358 0.3 0.343 0.00606 0.54 0.5902 0.961 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O03 compound treatment 0.362 0.0286 2.37 0.36 0.0231 2.04 3.1231 0.9972 1941576 CBMicro_031961 CCOc1cc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C4=NC(=O)\C(=C/c5ccc(O)c(OCC)c5)\S4)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O04 compound treatment 0.332 -0.00142 -0.12 0.335 -0.00194 -0.17 -0.2046 -0.9832 1941577 CBMicro_031962 [O-][N+](=O)c1cccc2C(=O)N(C(=O)c21)c3cccc(c3)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O05 compound treatment 0.327 -0.00642 -0.53 0.334 -0.00294 -0.26 -0.5608 -0.9456 1781937 CBMicro_031963 CN1C(=C(C(NC1=O)c2cccc(c2)[N+](=O)[O-])C(=O)OCCc3ccccc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O06 compound treatment 0.329 -0.00442 -0.37 0.331 -0.00594 -0.53 -0.6314 -0.9845 1160824 CBMicro_031964 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O07 compound treatment 0.325 -0.00842 -0.7 0.316 -0.0209 -1.86 -1.8062 -0.911 1941578 CBMicro_031965 COC(=O)c1ccccc1N2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O08 compound treatment 0.309 -0.0244 -2.03 0.319 -0.0179 -1.59 -2.5574 -0.9928 1667351 CBMicro_031966 Cc1ccc(c(OCC(=O)Nc2ccccc2F)c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O09 compound treatment 0.377 0.0436 3.62 0.373 0.0361 3.2 4.8183 0.9981 1941579 CBMicro_031967 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OCC)c3)C(=O)CCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O10 compound treatment 0.415 0.0816 6.77 0.421 0.0841 7.45 10.057 0.9989 1941580 CBMicro_031968 COC(=O)CN1C(=O)/C(=N\NC(=O)c2cc(C)n[nH]2)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O11 compound treatment 0.383 0.0496 4.12 0.382 0.0451 3.99 5.7345 0.9999 1941581 CBMicro_031969 Brc1ccccc1C(=O)NNC(=O)CCN2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O12 compound treatment 0.35 0.0166 1.38 0.341 0.00406 0.36 1.228 0.8631 1941582 CBMicro_031970 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O13 compound treatment 0.355 0.0216 1.79 0.345 0.00806 0.71 1.7722 0.9188 1941583 CBMicro_031971 OC(=O)c1ccccc1C(=O)NC2=NN(CC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O14 compound treatment 0.388 0.0546 4.53 0.376 0.0391 3.46 5.652 0.9912 1425256 CBMicro_031972 CCOc1cc(ccc1OC(=O)C2CC2)C3C(=C(C)NC4=C3C(=O)CC(C)(C)C4)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O15 compound treatment 0.32 -0.0134 -1.11 0.336 -9.35E-4 -0.08 -0.8464 -0.7576 1184520 CBMicro_031973 CC(C)(C)c1ccccc1OCC(=O)Nc2nccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O16 compound treatment 0.405 0.0716 5.94 0.409 0.0721 6.39 8.7179 0.9994 1941584 CBMicro_031974 CC(=C1C(=O)c2ccccc2C1=O)Nc3ccc(N)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O17 compound treatment 0.332 -0.00142 -0.12 0.328 -0.00894 -0.79 -0.6433 -0.8035 1274388 CBMicro_031975 Clc1ccccc1C(=O)Nc2c[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O18 compound treatment 0.327 -0.00642 -0.53 0.332 -0.00494 -0.44 -0.6861 -0.9952 1941585 CBMicro_031976 [O-][N+](=O)c1ccccc1N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O19 compound treatment 0.329 -0.00442 -0.37 0.33 -0.00694 -0.61 -0.694 -0.9696 1143731 CBMicro_031977 Cc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(O)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O20 compound treatment 0.327 -0.00642 -0.53 0.332 -0.00494 -0.44 -0.6861 -0.9952 1319470 CBMicro_031978 O=C(CCc1ccccc1)Nc2c[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O21 compound treatment 0.373 0.0396 3.29 0.376 0.0391 3.46 4.7715 0.9997 1941586 CBMicro_031979 [O-][N+](=O)c1ccc(Oc2ccc(cc2)C(=O)Nc3nc4ccccc4s3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O22 compound treatment 0.29 -0.0434 -3.6 0.293 -0.0439 -3.89 -5.3021 -0.9993 1866654 CBMicro_031980 Oc1ccc(cc1)N2C(=O)c3cccc4c(ccc(C2=O)c34)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O23 positive control 0.087 -0.246 -20.46 0.092 -0.245 -21.71 -29.8145 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 O24 positive control 0.092 -0.241 -20.04 0.098 -0.239 -21.17 -29.145 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P01 mock treatment 0.338 0.00458 0.38 0.338 0.00106 0.09 0.3356 0.8566 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P02 mock treatment 0.34 0.00658 0.55 0.341 0.00406 0.36 0.641 0.9796 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P03 compound treatment 0.344 0.0106 0.88 0.337 6.45E-5 0.01 0.6252 0.7117 1941587 CBMicro_031981 COc1ccccc1c2c(oc3c(CN4CC(C)OC(C)C4)c(O)ccc3c2=O)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P04 compound treatment 0.358 0.0246 2.04 0.356 0.0191 1.69 2.6376 0.9956 1238010 CBMicro_031982 Clc1cccc(NC(=O)Nc2ccc3OCCOc3c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P05 compound treatment 0.334 5.81E-4 0.05 0.339 0.00206 0.18 0.1635 0.8639 1310399 CBMicro_031983 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4ccccn4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P06 compound treatment 0.33 -0.00342 -0.28 0.332 -0.00494 -0.44 -0.51 -0.9781 1400016 CBMicro_031984 CC(=O)Oc1ccc2c3ccccc3c(=O)oc2c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P07 compound treatment 0.37 0.0366 3.04 0.363 0.0261 2.31 3.7807 0.9909 1941588 CBMicro_031985 C/C(=N\NC(=O)C1(C)CC1(Br)Br)/c2ccc(Br)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P08 compound treatment 0.323 -0.0104 -0.87 0.328 -0.00894 -0.79 -1.1716 -0.999 1267255 CBMicro_031986 OC1(N(CCNC(=O)Nc2ccccc2)C(=O)c3ccccc31)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P09 compound treatment 0.331 -0.00242 -0.2 0.33 -0.00694 -0.61 -0.5766 -0.8918 1941589 CBMicro_031987 CC1(CC1(Br)Br)C(=O)N/N=C/c2ccc3OCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P10 compound treatment 0.321 -0.0124 -1.03 0.325 -0.0119 -1.06 -1.477 -0.9999 1384301 CBMicro_031988 Clc1ccc(cc1)C23N(CCN3C(=O)c4ccccc42)C(=S)Nc5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P11 compound treatment 0.323 -0.0104 -0.87 0.328 -0.00894 -0.79 -1.1716 -0.999 1592027 CBMicro_031989 COc1cccc(c1)C2(CC2C(=O)Nc3ccccc3Cl)c4cccc(OC)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P12 compound treatment 0.338 0.00458 0.38 0.341 0.00406 0.36 0.5236 0.9996 1525922 CBMicro_031990 CCOC(=O)C(Oc1cc2oc(=O)c3CCCCc3c2cc1Cl)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P13 compound treatment 0.33 -0.00342 -0.28 0.33 -0.00694 -0.61 -0.6353 -0.9384 1635532 CBMicro_031991 COc1ccc(NC(=O)CC2CCCCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P14 compound treatment 0.338 0.00458 0.38 0.346 0.00906 0.8 0.8369 0.9417 1381893 CBMicro_031992 CCOC(=O)CSc1cc(C)nc2ccccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P15 compound treatment 0.328 -0.00542 -0.45 0.327 -0.00994 -0.88 -0.9407 -0.9514 1271964 CBMicro_031993 CCOc1ccccc1NC(=O)C2C3C2C4CCC3C4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P16 compound treatment 0.33 -0.00342 -0.28 0.335 -0.00194 -0.17 -0.322 -0.9709 1604667 CBMicro_031994 Cc1cnc2sc(C(=O)Nc3ccccc3)c(C(=O)O)n2c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P17 compound treatment 0.365 0.0316 2.62 0.377 0.0401 3.55 4.3645 0.9889 1941590 CBMicro_031995 COc1ccc2/C(=N/OC(=O)c3ccccc3OC)/CCc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P18 compound treatment 0.382 0.0486 4.03 0.374 0.0371 3.28 5.1745 0.9948 1941591 CBMicro_031996 [O-][N+](=O)c1ccccc1NC(=O)c2ccc(=O)oc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P19 compound treatment 0.349 0.0156 1.29 0.348 0.0111 0.98 1.608 0.9907 1941592 CBMicro_031997 COc1ccc(Oc2coc3cc(OS(=O)(=O)C)ccc3c2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P20 compound treatment 0.339 0.00558 0.46 0.332 -0.00494 -0.44 0.0183 0.0288 1401715 CBMicro_031998 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P21 compound treatment 0.344 0.0106 0.88 0.343 0.00606 0.54 1.0012 0.9722 1864140 CBMicro_031999 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)C(=O)OC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P22 compound treatment 0.323 -0.0104 -0.87 0.33 -0.00694 -0.61 -1.0463 -0.986 1941593 CBMicro_032000 Cn1c(/C=C(/OC(=O)c2ccc(F)cc2)\c3ccc(F)cc3)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P23 positive control 0.088 -0.245 -20.37 0.091 -0.246 -21.8 -29.8185 -0.9994 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.785 P24 positive control 0.095 -0.238 -19.79 0.095 -0.242 -21.44 -29.1569 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A01 mock treatment 0.333 -0.00326 -0.27 0.333 -0.00534 -0.47 -0.5261 -0.9647 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A02 mock treatment 0.336 -2.58E-4 -0.02 0.347 0.00866 0.77 0.5273 0.6871 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A03 compound treatment 0.318 -0.0183 -1.52 0.329 -0.00934 -0.83 -1.6573 -0.9595 1233140 CBMicro_032001 Brc1ccc(cc1)N2C(=O)C3CC=C(CC3C2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A04 compound treatment 0.324 -0.0123 -1.02 0.332 -0.00634 -0.56 -1.1171 -0.9609 1864176 CBMicro_032002 CC(C)(C)c1ccccc1OCC(=O)Nc2ncc(s2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A05 compound treatment 0.363 0.0267 2.22 0.365 0.0267 2.36 3.2403 0.9995 1941594 CBMicro_032003 COc1cccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(C)cc3C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A06 compound treatment 0.339 0.00274 0.23 0.339 6.56E-4 0.06 0.2021 0.8601 1941595 CBMicro_032004 CCCOc1ccc(cc1)N2C(=O)CC(N(Cc3ccc(OC)cc3)C(=O)/C=C/C(=O)O)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A07 compound treatment 0.317 -0.0193 -1.6 0.322 -0.0163 -1.45 -2.1547 -0.9988 1941596 CBMicro_032005 Cc1cccc(c1)N2C(=O)C3C4C=CC(C3C2=O)C4=C5C6CC7CC(C6)CC5C7 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A08 compound treatment 0.328 -0.00826 -0.69 0.334 -0.00434 -0.38 -0.757 -0.9628 1464165 CBMicro_032006 Cc1ccc(cc1)S(=O)(=O)NCC(N2CCOCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A09 compound treatment 0.339 0.00274 0.23 0.364 0.0257 2.27 1.7687 0.774 1471424 CBMicro_032007 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A10 compound treatment 0.351 0.0147 1.22 0.349 0.0107 0.94 1.5332 0.9918 1941597 CBMicro_032008 NC(=O)/C(=C/c1ccc(o1)c2cccc(c2)C(F)(F)F)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A11 compound treatment 0.823 0.487 40.41 0.825 0.487 43.13 59.0697 0.9995 1941598 CBMicro_032009 CCOc1ccc2S/C(=C/NC(C)C)/C(=O)c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A12 compound treatment 0.317 -0.0193 -1.6 0.321 -0.0173 -1.54 -2.2174 -0.9998 1941599 CBMicro_032010 Nc1nonc1n2nnc(C(=O)N/N=C/c3cccc(O)c3)c2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A13 compound treatment 0.324 -0.0123 -1.02 0.317 -0.0213 -1.89 -2.0571 -0.9577 1619018 CBMicro_032011 Cc1ccc(OC(=O)COc2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A14 compound treatment 0.33 -0.00626 -0.52 0.332 -0.00634 -0.56 -0.7649 -0.9992 1941600 CBMicro_032012 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A15 compound treatment 0.33 -0.00626 -0.52 0.33 -0.00834 -0.74 -0.8902 -0.9851 1941601 CBMicro_032013 [O-][N+](=O)c1ccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(Cl)cn4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A16 compound treatment 0.239 -0.0973 -8.07 0.256 -0.0823 -7.3 -10.8694 -0.9987 1941602 CBMicro_032014 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/c3ccc(cc3)N(C)C)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A17 compound treatment 0.33 -0.00626 -0.52 0.33 -0.00834 -0.74 -0.8902 -0.9851 1864273 CBMicro_032015 [O-][N+](=O)c1cccc(Nc2ncnc3ccccc23)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A18 compound treatment 0.329 -0.00726 -0.6 0.329 -0.00934 -0.83 -1.0116 -0.9878 1478039 CBMicro_032016 OC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)c3cccs3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A19 compound treatment 0.329 -0.00726 -0.6 0.328 -0.0103 -0.92 -1.0743 -0.9793 1140100 CBMicro_032017 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)O)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A20 compound treatment 0.332 -0.00426 -0.35 0.335 -0.00334 -0.3 -0.4595 -0.9962 1698218 CBMicro_032018 COc1cccc(c1)C(=O)Nc2cc(ccc2OC)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A21 compound treatment 0.323 -0.0133 -1.1 0.324 -0.0143 -1.27 -1.6771 -0.9974 1342554 CBMicro_032019 OCCNc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A22 compound treatment 0.33 -0.00626 -0.52 0.331 -0.00734 -0.65 -0.8276 -0.9938 1452735 CBMicro_032020 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(O)cc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A23 positive control 0.082 -0.254 -21.11 0.082 -0.256 -22.72 -30.9896 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 A24 positive control 0.084 -0.252 -20.94 0.084 -0.254 -22.54 -30.7469 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B01 mock treatment 0.329 -0.00726 -0.6 0.335 -0.00334 -0.3 -0.6356 -0.9466 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B02 mock treatment 0.343 0.00674 0.56 0.342 0.00366 0.32 0.6249 0.9662 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B03 compound treatment 0.322 -0.0143 -1.18 0.323 -0.0153 -1.36 -1.7985 -0.9976 1661438 CBMicro_032021 Cc1cc2nc(oc2cc1C)c3cccc(NC(=O)c4ccc(Br)o4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B04 compound treatment 0.34 0.00374 0.31 0.336 -0.00234 -0.21 0.0728 0.1948 1941603 CBMicro_032022 CCc1ccccc1NC=C2C(=O)CC(CC2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B05 compound treatment 0.342 0.00574 0.48 0.339 6.56E-4 0.06 0.3782 0.7875 1941604 CBMicro_032023 CCCCOc1ccc(cc1)C(=O)Nc2cc(ccc2OC)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B06 compound treatment 0.324 -0.0123 -1.02 0.324 -0.0143 -1.27 -1.6184 -0.9939 1386507 CBMicro_032024 OC(=O)c1cc(NC(=O)c2ccccc2Cl)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B07 compound treatment 0.346 0.00974 0.81 0.347 0.00866 0.77 1.1143 0.9997 1941605 CBMicro_032025 Clc1ccc(cc1)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B08 compound treatment 0.45 0.114 9.44 0.429 0.0907 8.03 12.358 0.9968 1941606 CBMicro_032026 [O-][N+](=O)c1ccc(N2CCOCC2)c(c1)n3nc(c4ccccc4)c5ccccc5c3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B09 compound treatment 0.32 -0.0163 -1.35 0.32 -0.0183 -1.63 -2.1039 -0.9957 1363829 CBMicro_032027 CN(C)S(=O)(=O)c1ccc-2c(c1)C(=C(C#N)C#N)c3cc(ccc32)S(=O)(=O)N(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B10 compound treatment 0.325 -0.0113 -0.93 0.324 -0.0143 -1.27 -1.5597 -0.9886 1476246 CBMicro_032028 C=CCNc1nc(cs1)c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B11 compound treatment 0.128 -0.208 -17.29 0.127 -0.211 -18.73 -25.4693 -0.9992 1941607 CBMicro_032029 CN(C)c1ccc(/C=C\2/SC(=S)N(NC(=O)c3ccccc3C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B12 compound treatment 0.321 -0.0153 -1.27 0.326 -0.0123 -1.09 -1.6692 -0.9973 1941608 CBMicro_032030 Cc1ccc(O)c(c1)N2C(=O)c3ccc(cc3C2=O)C(=O)c4cccc(c4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B13 compound treatment 0.34 0.00374 0.31 0.335 -0.00334 -0.3 0.0101 0.0236 1941609 CBMicro_032031 OC(=O)C(N1C(=O)/C(=C/C=C/c2ccccc2)/SC1=S)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B14 compound treatment 0.319 -0.0173 -1.43 0.318 -0.0203 -1.8 -2.2879 -0.9935 1563390 CBMicro_032032 CC(C)c1ccc(cc1)C2CC(=O)Nc3c2ccc4ccccc34 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B15 compound treatment 0.337 7.42E-4 0.06 0.333 -0.00534 -0.47 -0.2913 -0.61 1343620 CBMicro_032033 CC(=O)N(Cc1ccc2OCOc2c1)C3CC(=O)N(C3=O)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B16 compound treatment 0.331 -0.00526 -0.44 0.323 -0.0153 -1.36 -1.2702 -0.8894 1941610 CBMicro_032034 CC1(C)CN1S(=O)(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B17 compound treatment 0.336 -2.58E-4 -0.02 0.338 -3.44E-4 -0.03 -0.0367 -0.9852 1941611 CBMicro_032035 COc1ccc(/C=C/C(=O)Nc2ccc(C)c(c2)[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B18 compound treatment 0.331 -0.00526 -0.44 0.332 -0.00634 -0.56 -0.7062 -0.9922 1941612 CBMicro_032036 Clc1cccc(Cl)c1/C=C/2\SC(=NC2=O)N3CCOCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B19 compound treatment 0.317 -0.0193 -1.6 0.317 -0.0213 -1.89 -2.468 -0.9965 1029709 CBMicro_032037 Oc1ccccc1C(=O)NCCNC(=O)c2ccccc2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B20 compound treatment 0.332 -0.00426 -0.35 0.331 -0.00734 -0.65 -0.7102 -0.9589 1941613 CBMicro_032038 CCN/C(=N\CC)/SC1CC(=O)N(C1=O)c2cccc(OCC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B21 compound treatment 0.367 0.0307 2.55 0.366 0.0277 2.45 3.5377 0.9998 1941614 CBMicro_032039 COc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Br)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B22 compound treatment 0.341 0.00474 0.39 0.339 6.56E-4 0.06 0.3195 0.8029 1941615 CBMicro_032040 COCCOC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B23 positive control 0.082 -0.254 -21.11 0.081 -0.257 -22.81 -31.0523 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 B24 positive control 0.083 -0.253 -21.03 0.085 -0.253 -22.45 -30.7429 -0.9995 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C01 mock treatment 0.336 -2.58E-4 -0.02 0.339 6.56E-4 0.06 0.026 0.4191 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C02 mock treatment 0.352 0.0157 1.31 0.354 0.0157 1.39 1.9052 0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C03 compound treatment 0.319 -0.0173 -1.43 0.323 -0.0153 -1.36 -1.9746 -0.9997 1506148 CBMicro_032041 Clc1ccc(cc1Cl)N2C(=O)C3C4C=CC(C3C2=O)C4=C5CCCCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C04 compound treatment 0.357 0.0207 1.72 0.354 0.0157 1.39 2.1987 0.9943 1146130 CBMicro_032042 CCOc1cc(ccc1O)C2C(=C(C)NC(=C2C(=O)OC)C)C(=O)OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C05 compound treatment 0.337 7.42E-4 0.06 0.338 -3.44E-4 -0.03 0.022 0.3203 1941616 CBMicro_032043 CC(C)c1cccc(C(C)C)c1NC(=O)c2ccc(cc2)C(=O)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C06 compound treatment 0.322 -0.0143 -1.18 0.328 -0.0103 -0.92 -1.4852 -0.992 1941617 CBMicro_032044 Fc1cccc(Cl)c1/C=N/NC(=O)Cn2nnc(n2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C07 compound treatment 0.36 0.0237 1.97 0.342 0.00366 0.32 1.6228 0.8124 1600907 CBMicro_032045 CCOc1ccc(NC(=O)C2C3CCCCC=CC23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C08 compound treatment 0.334 -0.00226 -0.19 0.336 -0.00234 -0.21 -0.2794 -0.9987 1941618 CBMicro_032046 Cc1ccc(O)c(c1)N2C(=O)c3ccc(Oc4ccc(cc4)[N+](=O)[O-])cc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C09 compound treatment 0.329 -0.00726 -0.6 0.327 -0.0113 -1.01 -1.1369 -0.97 1864168 CBMicro_032047 [O-][N+](=O)c1ccccc1OCC(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C10 compound treatment 0.324 -0.0123 -1.02 0.324 -0.0143 -1.27 -1.6184 -0.9939 1941619 CBMicro_032048 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(NC(=O)c3ccc(Br)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C11 compound treatment 0.338 0.00174 0.14 0.335 -0.00334 -0.3 -0.1073 -0.3254 1941620 CBMicro_032049 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3ccc(C)o3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C12 compound treatment 0.383 0.0467 3.88 0.388 0.0497 4.4 5.8556 0.998 1941621 CBMicro_032050 Cc1nonc1/N=C\c2cc(I)cc(I)c2O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C13 compound treatment 0.335 -0.00126 -0.1 0.339 6.56E-4 0.06 -0.0327 -0.2738 1941622 CBMicro_032051 CC1=CC(=O)N(C1=O)c2ccc(cc2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C14 compound treatment 0.342 0.00574 0.48 0.331 -0.00734 -0.65 -0.1231 -0.1526 1941623 CBMicro_032052 Cc1ccccc1NC(=O)CCCN2C(=O)/C(=C/c3cccc4OCOc43)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C15 compound treatment 0.365 0.0287 2.39 0.363 0.0247 2.19 3.2323 0.999 1941624 CBMicro_032053 COc1ccc(cc1)c2nn(cc2/C=N/NS(=O)(=O)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C16 compound treatment 0.325 -0.0113 -0.93 0.325 -0.0133 -1.18 -1.4971 -0.9932 1650840 CBMicro_032054 Cc1cc(NC(=O)c2ccc3ccccc3c2)ccc1NC(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C17 compound treatment 0.342 0.00574 0.48 0.334 -0.00434 -0.38 0.0649 0.1059 1941625 CBMicro_032055 Fc1ccc(CN2C(=O)C3C(C4C=CC3C5C4C(=O)N(Cc6ccc(F)cc6)C5=O)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C18 compound treatment 0.332 -0.00426 -0.35 0.313 -0.0253 -2.25 -1.8381 -0.8084 1127630 CBMicro_032056 Cc1ccc(cc1)S(=O)(=O)NC(C)(C)CNC(c2ccccc2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C19 compound treatment 0.35 0.0137 1.14 0.349 0.0107 0.94 1.4745 0.9956 1941626 CBMicro_032057 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCOc4ccccc4)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C20 compound treatment 0.314 -0.0223 -1.85 0.32 -0.0183 -1.63 -2.4561 -0.998 1692187 CBMicro_032058 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C21 compound treatment 0.332 -0.00426 -0.35 0.337 -0.00134 -0.12 -0.3342 -0.8958 1532667 CBMicro_032059 Oc1ccc(cc1)C(=O)Nn2c(=O)c3cc4c(=O)n(NC(=O)c5ccc(O)cc5)c(=O)c4cc3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C22 compound treatment 0.329 -0.00726 -0.6 0.33 -0.00834 -0.74 -0.9489 -0.9948 1941627 CBMicro_032060 CCOc1ccc(cc1Br)C(=O)Nc2cc(OC)ccc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C23 positive control 0.08 -0.256 -21.27 0.08 -0.258 -22.89 -31.2323 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 C24 positive control 0.085 -0.251 -20.86 0.084 -0.254 -22.54 -30.6882 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D01 mock treatment 0.333 -0.00326 -0.27 0.337 -0.00134 -0.12 -0.2755 -0.9321 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D02 mock treatment 0.34 0.00374 0.31 0.344 0.00566 0.5 0.5741 0.9735 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D03 compound treatment 0.332 -0.00426 -0.35 0.334 -0.00434 -0.38 -0.5222 -0.9991 1941628 CBMicro_032061 CCCCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D04 compound treatment 0.331 -0.00526 -0.44 0.333 -0.00534 -0.47 -0.6435 -0.9992 1941629 CBMicro_032062 OC(=O)c1ccccc1NC(=O)c2cccc(c2)N3C(=O)c4cccc([N+](=O)[O-])c4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D05 compound treatment 0.33 -0.00626 -0.52 0.333 -0.00534 -0.47 -0.7022 -0.9989 1699639 CBMicro_032063 CC(=O)Oc1cccc(c1)C(=O)Nc2cc(C)on2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D06 compound treatment 0.508 0.172 14.26 0.522 0.184 16.28 21.5907 0.9978 1941630 CBMicro_032064 CCOc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Br)C2=O)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D07 compound treatment 0.326 -0.0103 -0.85 0.33 -0.00834 -0.74 -1.125 -0.9975 1941631 CBMicro_032065 [O-][N+](=O)c1ccc(Cl)c(/C=N/NC(=O)c2cc3ccccc3o2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D08 compound treatment 0.325 -0.0113 -0.93 0.329 -0.00934 -0.83 -1.2464 -0.9982 1719490 CBMicro_032066 OC(=O)c1cc(NC(=O)c2cccc(Br)c2)cc(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D09 compound treatment 0.366 0.0297 2.47 0.384 0.0457 4.05 4.607 0.9719 1941632 CBMicro_032067 CCCN(CCC)c1ccc(/C=N\NC(=O)C2COc3cc4ccccc4cc3O2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D10 compound treatment 0.333 -0.00326 -0.27 0.335 -0.00334 -0.3 -0.4008 -0.999 1447843 CBMicro_032068 Cc1cc(=O)oc2cc(OCC(=O)OCc3ccccc3)c(Cl)cc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D11 compound treatment 0.336 -2.58E-4 -0.02 0.333 -0.00534 -0.47 -0.35 -0.7383 1564226 CBMicro_032069 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D12 compound treatment 0.366 0.0297 2.47 0.363 0.0247 2.19 3.291 0.9981 1864189 CBMicro_032070 COC(=O)C1=C(C)NC(=C(C1c2ccc(OC)c(c2)[N+](=O)[O-])C(=O)OC)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D13 compound treatment 0.331 -0.00526 -0.44 0.33 -0.00834 -0.74 -0.8315 -0.9684 1174985 CBMicro_032071 COc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D14 compound treatment 0.337 7.42E-4 0.06 0.337 -0.00134 -0.12 -0.0407 -0.3032 1158478 CBMicro_032072 Cc1csc(n1)c2coc3cc(OCC(=O)O)cc(C)c3c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D15 compound treatment 0.309 -0.0273 -2.26 0.315 -0.0233 -2.07 -3.063 -0.999 1941633 CBMicro_032073 Ic1cccc(c1)C(=O)Nc2ccc3nn(nc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D16 compound treatment 0.326 -0.0103 -0.85 0.329 -0.00934 -0.83 -1.1877 -0.9999 1941634 CBMicro_032074 Cc1c(N2C(=O)S/C(=C/3\C(=O)Nc4ccccc34)/C2=O)c(=O)n(c5ccccc5)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D17 compound treatment 0.326 -0.0103 -0.85 0.329 -0.00934 -0.83 -1.1877 -0.9999 1941635 CBMicro_032075 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D18 compound treatment 0.318 -0.0183 -1.52 0.312 -0.0263 -2.33 -2.7226 -0.9781 1473932 CBMicro_032076 CCOc1cc(ccc1O)C2NC(=S)NC(=C2C(=O)Nc3ccc(Cl)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D19 compound treatment 0.331 -0.00526 -0.44 0.337 -0.00134 -0.12 -0.3929 -0.8683 1161513 CBMicro_032077 Cc1ccc(NC(=O)C2CCC(C)(C(=O)NN)C2(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D20 compound treatment 0.335 -0.00126 -0.1 0.339 6.56E-4 0.06 -0.0327 -0.2738 1941636 CBMicro_032078 N/C(=N/N=C/c1ccc2OCOc2c1)/c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D21 compound treatment 0.334 -0.00226 -0.19 0.337 -0.00134 -0.12 -0.2168 -0.976 1594118 CBMicro_032079 COc1cc2c(cc1NC(=O)CCN3C(=O)c4ccccc4C3=O)oc5ccccc52 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D22 compound treatment 0.342 0.00574 0.48 0.343 0.00466 0.41 0.6289 0.9974 1723514 CBMicro_032080 OC(=O)c1ccc(Cl)cc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccccc4c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D23 positive control 0.081 -0.255 -21.19 0.081 -0.257 -22.81 -31.111 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 D24 positive control 0.087 -0.249 -20.69 0.085 -0.253 -22.45 -30.5081 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E01 mock treatment 0.322 -0.0143 -1.18 0.33 -0.00834 -0.74 -1.3599 -0.9743 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E02 mock treatment 0.342 0.00574 0.48 0.346 0.00766 0.68 0.8169 0.9851 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E03 compound treatment 0.332 -0.00426 -0.35 0.328 -0.0103 -0.92 -0.8982 -0.9142 1326495 CBMicro_032081 COc1ccc(OC)c(NC(=O)C2C3C2C4CCC3C4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E04 compound treatment 0.325 -0.0113 -0.93 0.324 -0.0143 -1.27 -1.5597 -0.9886 1941637 CBMicro_032082 Brc1ccc(cc1)N2C(=O)CC(NCC#N)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E05 compound treatment 0.328 -0.00826 -0.69 0.325 -0.0133 -1.18 -1.321 -0.9664 1460992 CBMicro_032083 COC(=O)c1ccc(COc2ccc3c4CCCCc4c(=O)oc3c2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E06 compound treatment 0.32 -0.0163 -1.35 0.322 -0.0163 -1.45 -1.9786 -0.9994 1941638 CBMicro_032084 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(c3nc4ccccc4o3)c(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E07 compound treatment 0.328 -0.00826 -0.69 0.333 -0.00534 -0.47 -0.8196 -0.9837 1262934 CBMicro_032085 COc1ccc(cc1)c2cc(=O)oc3c(C)c(OC(=O)C)ccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E08 compound treatment 0.328 -0.00826 -0.69 0.325 -0.0133 -1.18 -1.321 -0.9664 1941639 CBMicro_032086 Cc1occc1C(=O)N/N=C/c2ccc[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E09 compound treatment 0.302 -0.0343 -2.84 0.315 -0.0233 -2.07 -3.4739 -0.9878 1295056 CBMicro_032087 CCOc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E10 compound treatment 0.373 0.0367 3.05 0.382 0.0437 3.87 4.8926 0.9931 1941640 CBMicro_032088 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E11 compound treatment 0.33 -0.00626 -0.52 0.327 -0.0113 -1.01 -1.0782 -0.9528 1941641 CBMicro_032089 COc1ccc(NC(=O)c2ccc(Br)o2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E12 compound treatment 0.385 0.0487 4.05 0.379 0.0407 3.6 5.409 0.9983 1941642 CBMicro_032090 Cc1ccccc1C(=O)NN2C(=O)/C(=C\c3ccncc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E13 compound treatment 0.328 -0.00826 -0.69 0.331 -0.00734 -0.65 -0.945 -0.9997 1402724 CBMicro_032091 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)c4cccs4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E14 compound treatment 0.311 -0.0253 -2.1 0.315 -0.0233 -2.07 -2.9456 -1.0 1941643 CBMicro_032092 CC1=C(C(NC(=S)N1)c2ccccc2Br)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E15 compound treatment 0.351 0.0147 1.22 0.354 0.0157 1.39 1.8465 0.998 1782499 CBMicro_032093 Clc1cccc(c1)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E16 compound treatment 0.321 -0.0153 -1.27 0.336 -0.00234 -0.21 -1.0426 -0.8122 1941644 CBMicro_032094 [O-][N+](=O)c1ccccc1/C=N/NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E17 compound treatment 0.329 -0.00726 -0.6 0.328 -0.0103 -0.92 -1.0743 -0.9793 1212953 CBMicro_032095 COc1ccc2c(c1)c(=O)oc3cc(OC(=O)C)ccc32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E18 compound treatment 0.395 0.0587 4.88 0.397 0.0587 5.2 7.124 0.9995 1351263 CBMicro_032096 COC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E19 compound treatment 0.348 0.0117 0.97 0.348 0.00966 0.86 1.2944 0.9979 1304320 CBMicro_032097 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cc(OC)c(OC)cc4C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E20 compound treatment 0.327 -0.00926 -0.77 0.329 -0.00934 -0.83 -1.129 -0.9993 1467330 CBMicro_032098 Cc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3ccccc3)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E21 compound treatment 0.337 7.42E-4 0.06 0.346 0.00766 0.68 0.5233 0.7681 1176672 CBMicro_032099 CCOc1ccc(cc1)n2nc3ccc(NC(=O)c4ccco4)cc3n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E22 compound treatment 0.338 0.00174 0.14 0.329 -0.00934 -0.83 -0.4833 -0.5749 1663904 CBMicro_032100 COc1cc2ccccc2cc1C(=O)Nc3ccc(cc3)N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E23 positive control 0.082 -0.254 -21.11 0.082 -0.256 -22.72 -30.9896 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 E24 positive control 0.087 -0.249 -20.69 0.087 -0.251 -22.27 -30.3827 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F01 mock treatment 0.329 -0.00726 -0.6 0.333 -0.00534 -0.47 -0.7609 -0.9929 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F02 mock treatment 0.338 0.00174 0.14 0.339 6.56E-4 0.06 0.1434 0.9199 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F03 compound treatment 0.333 -0.00326 -0.27 0.334 -0.00434 -0.38 -0.4635 -0.9851 1941645 CBMicro_032101 CCOCCOC(=O)C1=C(C)N(C)C(=O)NC1c2cccc(c2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F04 compound treatment 0.341 0.00474 0.39 0.326 -0.0123 -1.09 -0.4952 -0.4259 1679866 CBMicro_032102 COc1ccc(CN(C2CC(=O)N(C2=O)c3ccc(F)cc3)C(=S)Nc4ccccc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F05 compound treatment 0.323 -0.0133 -1.1 0.322 -0.0163 -1.45 -1.8025 -0.9908 1941646 CBMicro_032103 CC/C(=C\1/C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2)/NCc4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F06 compound treatment 0.612 0.276 22.89 0.63 0.292 25.85 34.4636 0.9982 1941647 CBMicro_032104 Oc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Br)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F07 compound treatment 0.386 0.0497 4.13 0.377 0.0387 3.43 5.3424 0.9957 1941648 CBMicro_032105 Cc1ccccc1C(=O)NN2C(=O)/C(=C\c3cccs3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F08 compound treatment 0.345 0.00874 0.73 0.342 0.00366 0.32 0.7423 0.934 1941649 CBMicro_032106 COc1ccc(CCN(C2CC(=O)N(C2=O)c3cccc(Cl)c3)C(=O)CCC(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F09 compound treatment 0.341 0.00474 0.39 0.344 0.00566 0.5 0.6328 0.9928 1394684 CBMicro_032107 O=C(Cc1cccs1)Nc2cccc3C(=O)N(C(=O)c32)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F10 compound treatment 0.224 -0.112 -9.32 0.217 -0.121 -10.75 -14.1939 -0.9975 1941650 CBMicro_032108 Cc1cccc(N2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F11 compound treatment 0.406 0.0697 5.79 0.377 0.0387 3.43 6.5165 0.9686 1941651 CBMicro_032109 NC(=O)/C(=C/c1ccc(o1)c2ccc(Cl)c(Cl)c2)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F12 compound treatment 0.742 0.406 33.68 0.748 0.41 36.3 49.4895 0.9993 1941652 CBMicro_032110 OC(=O)CCCCCN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccccc23)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F13 compound treatment 0.336 -2.58E-4 -0.02 0.336 -0.00234 -0.21 -0.162 -0.7759 1781923 CBMicro_032111 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3[N+](=O)[O-])C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F14 compound treatment 0.332 -0.00426 -0.35 0.33 -0.00834 -0.74 -0.7728 -0.9429 1781477 CBMicro_032112 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3c[nH]c(=O)[nH]c3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F15 compound treatment 0.331 -0.00526 -0.44 0.335 -0.00334 -0.3 -0.5182 -0.9822 1941653 CBMicro_032113 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccc(C)c(C)c3)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F16 compound treatment 0.328 -0.00826 -0.69 0.331 -0.00734 -0.65 -0.945 -0.9997 1730157 CBMicro_032114 Cc1ccc2nc(oc(=O)c2c1)c3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F17 compound treatment 0.323 -0.0133 -1.1 0.326 -0.0123 -1.09 -1.5518 -1.0 1941654 CBMicro_032115 CCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccccc3)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F18 compound treatment 0.331 -0.00526 -0.44 0.332 -0.00634 -0.56 -0.7062 -0.9922 1941655 CBMicro_032116 CCCOC(=O)C(C)Sc1n[nH]c(=O)[nH]c1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F19 compound treatment 0.323 -0.0133 -1.1 0.324 -0.0143 -1.27 -1.6771 -0.9974 1941656 CBMicro_032117 CCCc1nc2ccccc2n1C(=O)/C=C\C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F20 compound treatment 0.341 0.00474 0.39 0.347 0.00866 0.77 0.8208 0.9519 1459748 CBMicro_032118 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F21 compound treatment 0.337 7.42E-4 0.06 0.361 0.0227 2.01 1.4633 0.7285 1388276 CBMicro_032119 Cc1nn(C(=O)c2cccnc2)c(C)c1Sc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F22 compound treatment 0.328 -0.00826 -0.69 0.331 -0.00734 -0.65 -0.945 -0.9997 1359087 CBMicro_032120 CCC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F23 positive control 0.084 -0.252 -20.94 0.083 -0.255 -22.63 -30.8095 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 F24 positive control 0.088 -0.248 -20.61 0.088 -0.25 -22.19 -30.2614 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G01 mock treatment 0.323 -0.0133 -1.1 0.327 -0.0113 -1.01 -1.4891 -0.999 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G02 mock treatment 0.332 -0.00426 -0.35 0.335 -0.00334 -0.3 -0.4595 -0.9962 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G03 compound treatment 0.324 -0.0123 -1.02 0.326 -0.0123 -1.09 -1.4931 -0.9993 1941657 CBMicro_032121 [O-][N+](=O)c1ccccc1NC(=O)CC2SC(=N)NC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G04 compound treatment 0.326 -0.0103 -0.85 0.332 -0.00634 -0.56 -0.9997 -0.9797 1941658 CBMicro_032122 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5cccc(c5)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G05 compound treatment 0.328 -0.00826 -0.69 0.343 0.00466 0.41 -0.193 -0.2412 1941659 CBMicro_032123 COc1cc(/C=N/n2cnnc2)cc(Br)c1OCCOc3ccc(cc3)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G06 compound treatment 0.322 -0.0143 -1.18 0.319 -0.0193 -1.71 -2.0492 -0.9836 1941660 CBMicro_032124 Cc1ccc(OCC(=O)NNC(=O)c2ccco2)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G07 compound treatment 0.311 -0.0253 -2.1 0.316 -0.0223 -1.98 -2.8829 -0.9996 1222256 CBMicro_032125 COc1ccccc1NC(=O)C2CC3c4ccccc4C2c5ccccc35 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G08 compound treatment 0.324 -0.0123 -1.02 0.323 -0.0153 -1.36 -1.6811 -0.9898 1600259 CBMicro_032126 Cc1ccc2nc(oc(=O)c2c1)c3ccc(cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G09 compound treatment 0.382 0.0457 3.8 0.396 0.0577 5.11 6.2982 0.9893 1431705 CBMicro_032127 CCOc1ccccc1C2NC(=O)c3c4CCN(C)Cc4sc3N2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G10 compound treatment 0.137 -0.199 -16.54 0.139 -0.199 -17.67 -24.189 -0.9995 1941661 CBMicro_032128 COc1ccc(cc1)C2=CC(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G11 compound treatment 0.432 0.0957 7.95 0.437 0.0987 8.74 11.8027 0.9989 1941662 CBMicro_032129 OC(=O)CCCCCN1C(=O)/C(=C/c2cccc(F)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G12 compound treatment 0.455 0.119 9.86 0.451 0.113 9.98 14.0302 1.0 1941663 CBMicro_032130 COc1ccc(/C=C/2\SC(=O)NC2=S)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G13 compound treatment 0.375 0.0387 3.22 0.392 0.0537 4.76 5.6367 0.9819 1941664 CBMicro_032131 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(F)cc3)C(=O)OCCOc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G14 compound treatment 0.314 -0.0223 -1.85 0.318 -0.0203 -1.8 -2.5815 -0.9999 1252413 CBMicro_032132 CC(C)(C)NC(=O)c1cccc(c1)C(=O)Nc2cccc(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G15 compound treatment 0.436 0.0997 8.28 0.47 0.132 11.67 14.1054 0.9859 1941665 CBMicro_032133 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C\3/SC(=S)N(CC(=O)O)C3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G16 compound treatment 0.323 -0.0133 -1.1 0.324 -0.0143 -1.27 -1.6771 -0.9974 1781929 CBMicro_032134 CCCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G17 compound treatment 0.341 0.00474 0.39 0.342 0.00366 0.32 0.5075 0.9953 1941666 CBMicro_032135 Cc1cccc(N/C=C/C(=O)c2ccc(Br)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G18 compound treatment 0.376 0.0397 3.3 0.375 0.0367 3.25 4.63 1.0 1941667 CBMicro_032136 CC1(C)CC(=O)c2c(C1)oc3ccc(NS(=O)(=O)c4cccc(c4)[N+](=O)[O-])cc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G19 compound treatment 0.332 -0.00426 -0.35 0.335 -0.00334 -0.3 -0.4595 -0.9962 1941668 CBMicro_032137 CN1C(=O)N(C)C(=O)C(=CNCC2CCN(CC2)C(=S)Nc3ccccc3)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G20 compound treatment 0.324 -0.0123 -1.02 0.327 -0.0113 -1.01 -1.4304 -1.0 1371499 CBMicro_032138 COc1cc2ccccc2cc1C(=O)Nc3ccc(Br)cn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G21 compound treatment 0.327 -0.00926 -0.77 0.331 -0.00734 -0.65 -1.0037 -0.9966 1363442 CBMicro_032139 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(F)cc3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G22 compound treatment 0.326 -0.0103 -0.85 0.33 -0.00834 -0.74 -1.125 -0.9975 1941669 CBMicro_032140 CCOc1ccc(cc1)N2C(=O)S/C(=C\C=C\c3ccccc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G23 positive control 0.085 -0.251 -20.86 0.084 -0.254 -22.54 -30.6882 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 G24 positive control 0.091 -0.245 -20.36 0.089 -0.249 -22.1 -30.0226 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H01 mock treatment 0.327 -0.00926 -0.77 0.33 -0.00834 -0.74 -1.0663 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H02 mock treatment 0.334 -0.00226 -0.19 0.337 -0.00134 -0.12 -0.2168 -0.976 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H03 compound treatment 0.332 -0.00426 -0.35 0.331 -0.00734 -0.65 -0.7102 -0.9589 1941670 CBMicro_032141 CC/C(=C\1/C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2)/NCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H04 compound treatment 0.378 0.0417 3.47 0.379 0.0407 3.6 4.9981 0.9998 1509073 CBMicro_032142 CC(=C1C(=O)c2ccccc2C1=O)N3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H05 compound treatment 0.323 -0.0133 -1.1 0.325 -0.0133 -1.18 -1.6145 -0.9994 1517142 CBMicro_032143 COc1cc2ccccc2cc1C(=O)Nc3cccc(c4nc5cc(C)cc(C)c5o4)c3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H06 compound treatment 0.309 -0.0273 -2.26 0.314 -0.0243 -2.16 -3.1256 -0.9997 1180617 CBMicro_032144 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(Br)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H07 compound treatment 0.323 -0.0133 -1.1 0.331 -0.00734 -0.65 -1.2385 -0.9686 1490885 CBMicro_032145 CC1C=C(C)CC(C1C(=O)O)C(=O)Nc2cccnc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H08 compound treatment 0.315 -0.0213 -1.76 0.321 -0.0173 -1.54 -2.3348 -0.9976 1433185 CBMicro_032146 COC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC=C)c2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H09 compound treatment 0.342 0.00574 0.48 0.331 -0.00734 -0.65 -0.1231 -0.1526 1257041 CBMicro_032147 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc3nn(nc3c2)c4ccc(C)c(C)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H10 compound treatment 0.324 -0.0123 -1.02 0.33 -0.00834 -0.74 -1.2425 -0.9877 1941671 CBMicro_032148 CCOc1cc(/C=N/NC(=O)c2cccs2)ccc1OC(=O)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H11 compound treatment 1.072 0.736 61.08 1.083 0.745 65.99 89.8544 0.9993 1941672 CBMicro_032149 Cc1ccc(/C=C/2\SC(=S)N(CC(=O)O)C2=O)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H12 compound treatment 0.295 -0.0413 -3.43 0.306 -0.0323 -2.87 -4.4488 -0.9961 1941673 CBMicro_032150 CCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cc(OC)ccc3OC)/c4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H13 compound treatment 0.089 -0.247 -20.53 0.09 -0.248 -22.01 -30.0773 -0.9994 1941674 CBMicro_032151 Clc1cccc(c1)C2=CC(=O)C=CC2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H14 compound treatment 0.331 -0.00526 -0.44 0.337 -0.00134 -0.12 -0.3929 -0.8683 1405733 CBMicro_032152 COc1ccc(CCN(C2CC(=O)N(C2=O)c3ccc(Cl)cc3)C(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H15 compound treatment 0.335 -0.00126 -0.1 0.332 -0.00634 -0.56 -0.4714 -0.8244 1617066 CBMicro_032153 CCOc1cccc(c1)C(=O)Nc2ccc(cc2)c3nc4cc(Cl)ccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H16 compound treatment 0.316 -0.0203 -1.68 0.322 -0.0163 -1.45 -2.2134 -0.9972 1941675 CBMicro_032154 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(cc3)C(=O)OC)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H17 compound treatment 0.327 -0.00926 -0.77 0.33 -0.00834 -0.74 -1.0663 -0.9998 1523483 CBMicro_032155 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3ccccc3c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H18 compound treatment 0.334 -0.00226 -0.19 0.335 -0.00334 -0.3 -0.3421 -0.9756 1666145 CBMicro_032156 CCC(=O)N(CCc1ccccc1)C2CC(=O)N(C2=O)c3ccc(OC)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H19 compound treatment 0.325 -0.0113 -0.93 0.333 -0.00534 -0.47 -0.9958 -0.9504 1941676 CBMicro_032157 NNC(=O)/C(=C\c1ccc(Br)cc1)/NC(=O)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H20 compound treatment 0.316 -0.0203 -1.68 0.316 -0.0223 -1.98 -2.5894 -0.9967 1941677 CBMicro_032158 O=C(CSc1nnc(c2ccccc2)n1c3ccccc3)N/N=C/C=C/c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H21 compound treatment 0.603 0.267 22.14 0.599 0.261 23.1 31.9927 0.9998 1941678 CBMicro_032159 CC(=O)NN1C(=O)/C(=C/c2cccc(O)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H22 compound treatment 0.348 0.0117 0.97 0.343 0.00466 0.41 0.9811 0.9268 1941679 CBMicro_032160 COC(=O)C1CC(=CC(C)C1C(=O)O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H23 positive control 0.086 -0.25 -20.78 0.085 -0.253 -22.45 -30.5668 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 H24 positive control 0.093 -0.243 -20.2 0.09 -0.248 -22.01 -29.8425 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I01 mock treatment 0.336 -2.58E-4 -0.02 0.338 -3.44E-4 -0.03 -0.0367 -0.9852 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I02 mock treatment 0.344 0.00774 0.64 0.347 0.00866 0.77 0.9969 0.9961 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I03 compound treatment 0.341 0.00474 0.39 0.345 0.00666 0.59 0.6955 0.9807 1324386 CBMicro_032161 COc1ccc(OC)c(NC(=O)C2CC2(c3cccc(C)c3)c4cccc(C)c4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I04 compound treatment 0.4 0.0637 5.29 0.406 0.0677 6.0 7.9815 0.9981 1941680 CBMicro_032162 COc1cccc(/C=C/2\SC(=S)N(C2=O)c3cccc(C)c3C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I05 compound treatment 0.331 -0.00526 -0.44 0.336 -0.00234 -0.21 -0.4555 -0.9423 1426713 CBMicro_032163 CCc1cc(=O)oc2c(C)c(OC(=O)C)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I06 compound treatment 0.396 0.0597 4.96 0.404 0.0657 5.82 7.6214 0.9968 1941681 CBMicro_032164 [O-][N+](=O)c1ccc(cc1)c2ccc(o2)C(=O)Nc3cccc(NC(=O)c4ccc(Cl)cc4Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I07 compound treatment 0.338 0.00174 0.14 0.341 0.00266 0.24 0.2687 0.9726 1941682 CBMicro_032165 CCOC(=O)c1[nH]nc2C(=O)N(C(=O)c12)c3ccc(OC)c(Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I08 compound treatment 0.31 -0.0263 -2.18 0.311 -0.0273 -2.42 -3.2549 -0.9986 1367727 CBMicro_032166 Fc1ccc(cc1)N2C(=O)CC(N(Cc3ccc4OCOc4c3)C(=S)Nc5ccccc5)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I09 compound treatment 0.332 -0.00426 -0.35 0.325 -0.0133 -1.18 -1.0862 -0.88 1350276 CBMicro_032167 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I10 compound treatment 0.335 -0.00126 -0.1 0.341 0.00266 0.24 0.0926 0.3596 1941683 CBMicro_032168 Nc1nonc1n2nnc(C(=O)N/N=C/c3ccc(O)cc3)c2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I11 compound treatment 0.369 0.0327 2.72 0.399 0.0607 5.38 5.7231 0.9501 1537094 CBMicro_032169 COc1cccc(c1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(Br)cc4C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I12 compound treatment 0.343 0.00674 0.56 0.345 0.00666 0.59 0.8129 0.9997 1941684 CBMicro_032170 Clc1ccc(NC2=CC(=O)N(C2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I13 compound treatment 0.419 0.0827 6.87 0.424 0.0857 7.59 10.2249 0.9988 1941685 CBMicro_032171 COc1ccc(/C=C/2\SC(=O)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I14 compound treatment 0.355 0.0187 1.56 0.359 0.0207 1.83 2.3946 0.9967 1941686 CBMicro_032172 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I15 compound treatment 1.13 0.794 65.9 1.153 0.815 72.2 97.6458 0.999 1941687 CBMicro_032173 CC(N1C(=O)/C(=C/c2cccs2)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I16 compound treatment 0.37 0.0337 2.8 0.368 0.0297 2.63 3.8392 0.9995 1941688 CBMicro_032174 COc1ccc(CCN/C(=N\c2ccccc2)/SC3CC(=O)N(C3=O)c4ccc(F)cc4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I17 compound treatment 0.317 -0.0193 -1.6 0.316 -0.0223 -1.98 -2.5307 -0.9944 1941689 CBMicro_032175 CCOC(=O)c1[nH]nc2C(=O)N(C(=O)c12)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I18 compound treatment 0.343 0.00674 0.56 0.36 0.0217 1.92 1.7529 0.8768 1941690 CBMicro_032176 COc1ccc(/C=C/C(=O)Nc2ccc(cc2OC)[N+](=O)[O-])cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I19 compound treatment 0.331 -0.00526 -0.44 0.337 -0.00134 -0.12 -0.3929 -0.8683 1941691 CBMicro_032177 C/C(=N\NC(=O)c1cccc(O)c1)/CC(=O)N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I20 compound treatment 0.369 0.0327 2.72 0.383 0.0447 3.96 4.7204 0.9832 1378160 CBMicro_032178 COc1cc2ccccc2cc1C(=O)Nc3ccc(Cc4ccncc4)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I21 compound treatment 0.33 -0.00626 -0.52 0.333 -0.00534 -0.47 -0.7022 -0.9989 1941692 CBMicro_032179 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccc(cc3)c4ccccc4)s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I22 compound treatment 0.347 0.0107 0.89 0.351 0.0127 1.12 1.4237 0.9935 1698316 CBMicro_032180 CC(=O)Oc1ccc(cc1)C(=O)Nc2cc(Cl)ccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I23 positive control 0.085 -0.251 -20.86 0.084 -0.254 -22.54 -30.6882 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 I24 positive control 0.091 -0.245 -20.36 0.09 -0.248 -22.01 -29.9599 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J01 mock treatment 0.3 -0.0363 -3.01 0.323 -0.0153 -1.36 -3.09 -0.9355 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J02 mock treatment 0.339 0.00274 0.23 0.344 0.00566 0.5 0.5154 0.9362 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J03 compound treatment 0.337 7.42E-4 0.06 0.34 0.00166 0.15 0.1473 0.9256 1522170 CBMicro_032181 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3ccc(cc3)c4nc5ccccc5o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J04 compound treatment 0.372 0.0357 2.97 0.37 0.0317 2.81 4.0819 0.9996 1941693 CBMicro_032182 Brc1ccccc1C(=O)NN2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J05 compound treatment 0.37 0.0337 2.8 0.364 0.0257 2.27 3.5885 0.9946 1507048 CBMicro_032183 Cc1ccccc1C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J06 compound treatment 0.33 -0.00626 -0.52 0.334 -0.00434 -0.38 -0.6396 -0.9891 1941694 CBMicro_032184 Oc1cccc(/N=C/2\CSC(=O)N2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J07 compound treatment 0.324 -0.0123 -1.02 0.334 -0.00434 -0.38 -0.9918 -0.9115 1941695 CBMicro_032185 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)n4cnc5ccccc45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J08 compound treatment 0.31 -0.0263 -2.18 0.315 -0.0233 -2.07 -3.0043 -0.9997 1211690 CBMicro_032186 Brc1ccc(o1)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J09 compound treatment 0.326 -0.0103 -0.85 0.335 -0.00334 -0.3 -0.8117 -0.9002 1941696 CBMicro_032187 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cccs3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J10 compound treatment 0.31 -0.0263 -2.18 0.319 -0.0193 -1.71 -2.7536 -0.9929 1941697 CBMicro_032188 CC1=C(C(NC(=S)N1)c2ccc(F)cc2)C(=O)Nc3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J11 compound treatment 0.331 -0.00526 -0.44 0.334 -0.00434 -0.38 -0.5809 -0.998 1941698 CBMicro_032189 O=C(N/N=C/C=C/c1ccccc1)c2cc(n[nH]2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J12 compound treatment 0.31 -0.0263 -2.18 0.309 -0.0293 -2.6 -3.3803 -0.9962 1941699 CBMicro_032190 OC(C(=O)N/N=C/c1c[nH]c2ccc(Br)cc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J13 compound treatment 0.361 0.0247 2.05 0.354 0.0157 1.39 2.4335 0.9818 1153617 CBMicro_032191 CC(Oc1ccccc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J14 compound treatment 0.333 -0.00326 -0.27 0.348 0.00966 0.86 0.4139 0.4611 1186498 CBMicro_032192 Cc1cc(C)c2oc(nc2c1)c3ccc(C)c(NC(=O)c4ccc(Br)o4)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J15 compound treatment 0.597 0.261 21.65 0.613 0.275 24.34 32.5178 0.9983 1941700 CBMicro_032193 Oc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Br)C2=O)cc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J16 compound treatment 0.305 -0.0313 -2.6 0.314 -0.0243 -2.16 -3.3605 -0.9958 1337177 CBMicro_032194 Cc1cc(OCC(=O)NC2CC(C)(C)NC(C)(C)C2)ccc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J17 compound treatment 0.33 -0.00626 -0.52 0.332 -0.00634 -0.56 -0.7649 -0.9992 1146167 CBMicro_032195 OC(=O)c1ccc(cc1)n2c(=O)c3ccccc3c4ccccc4c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J18 compound treatment 0.353 0.0167 1.39 0.361 0.0227 2.01 2.4026 0.9839 1941701 CBMicro_032196 Oc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C4=NC(=O)\C(=C/c5ccc(O)cc5)\S4)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J19 compound treatment 0.316 -0.0203 -1.68 0.328 -0.0103 -0.92 -1.8374 -0.9593 1518161 CBMicro_032197 Brc1ccccc1C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J20 compound treatment 0.334 -0.00226 -0.19 0.337 -0.00134 -0.12 -0.2168 -0.976 1941702 CBMicro_032198 Cc1c(N2C(=O)S/C(=C\c3ccc(cc3)[N+](=O)[O-])/C2=O)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J21 compound treatment 0.333 -0.00326 -0.27 0.338 -3.44E-4 -0.03 -0.2128 -0.7818 1136068 CBMicro_032199 Cc1ccc(cc1C)N2C(=O)c3ccc(cc3C2=O)c4nc5c(C)cccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J22 compound treatment 0.335 -0.00126 -0.1 0.336 -0.00234 -0.21 -0.2207 -0.9494 1941703 CBMicro_032200 CCCCCN1C(=O)/C(=C/2\SC(=S)NC2=O)/c3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J23 positive control 0.085 -0.251 -20.86 0.084 -0.254 -22.54 -30.6882 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 J24 positive control 0.092 -0.244 -20.28 0.089 -0.249 -22.1 -29.9639 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K01 mock treatment 0.331 -0.00526 -0.44 0.334 -0.00434 -0.38 -0.5809 -0.998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K02 mock treatment 0.337 7.42E-4 0.06 0.339 6.56E-4 0.06 0.0847 0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K03 compound treatment 0.328 -0.00826 -0.69 0.331 -0.00734 -0.65 -0.945 -0.9997 1941704 CBMicro_032201 CCN1CCOC(C(C1C(=O)OC)C(=O)OC)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K04 compound treatment 0.337 7.42E-4 0.06 0.337 -0.00134 -0.12 -0.0407 -0.3032 1941705 CBMicro_032202 COc1ccc(OCC(=O)N/N=C/c2ccc(C)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K05 compound treatment 0.331 -0.00526 -0.44 0.334 -0.00434 -0.38 -0.5809 -0.998 1390958 CBMicro_032203 COC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K06 compound treatment 0.326 -0.0103 -0.85 0.329 -0.00934 -0.83 -1.1877 -0.9999 1941706 CBMicro_032204 COc1ccc(C/C(=N/OC(=O)c2ccco2)/N)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K07 compound treatment 0.331 -0.00526 -0.44 0.333 -0.00534 -0.47 -0.6435 -0.9992 1121838 CBMicro_032205 COc1ccc(OC)c(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K08 compound treatment 0.322 -0.0143 -1.18 0.328 -0.0103 -0.92 -1.4852 -0.992 1941707 CBMicro_032206 O=C1CC(N2CCCCC2)C(=O)N1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K09 compound treatment 0.295 -0.0413 -3.43 0.315 -0.0233 -2.07 -3.8848 -0.9708 1941708 CBMicro_032207 Clc1ccc(/C=N/NC(=O)CSc2nc3ccccc3[nH]2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K10 compound treatment 0.328 -0.00826 -0.69 0.341 0.00266 0.24 -0.3183 -0.4391 1741483 CBMicro_032208 COc1ccc(cc1)N2C(=O)CC(N(CCc3ccccc3)C(=S)Nc4ccccc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K11 compound treatment 0.328 -0.00826 -0.69 0.338 -3.44E-4 -0.03 -0.5063 -0.7378 1941709 CBMicro_032209 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nc2ccc3nn(nc3c2)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K12 compound treatment 0.319 -0.0173 -1.43 0.319 -0.0193 -1.71 -2.2253 -0.996 1780384 CBMicro_032210 [O-][N+](=O)c1cccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(Cl)cn4)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K13 compound treatment 0.335 -0.00126 -0.1 0.342 0.00366 0.32 0.1553 0.4561 1941710 CBMicro_032211 COCCOC(=O)c1ccc(NC(=O)COc2cccc(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K14 compound treatment 0.324 -0.0123 -1.02 0.332 -0.00634 -0.56 -1.1171 -0.9609 1941711 CBMicro_032212 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3ccc(F)cc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K15 compound treatment 0.422 0.0857 7.12 0.425 0.0867 7.68 10.4637 0.9993 1941712 CBMicro_032213 Brc1ccccc1C(=O)NNC(=O)CN2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K16 compound treatment 0.325 -0.0113 -0.93 0.332 -0.00634 -0.56 -1.0584 -0.9704 1561614 CBMicro_032214 CCC(=O)N(Cc1ccco1)C2CC(=O)N(C2=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K17 compound treatment 0.319 -0.0173 -1.43 0.324 -0.0143 -1.27 -1.912 -0.9982 1941713 CBMicro_032215 CC(C)C(=O)N1N=C(CC1(O)C(F)(F)F)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K18 compound treatment 0.316 -0.0203 -1.68 0.325 -0.0133 -1.18 -2.0254 -0.9851 1941714 CBMicro_032216 COc1ccccc1C(=O)Nc2ncc(s2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K19 compound treatment 0.371 0.0347 2.88 0.378 0.0397 3.51 4.5245 0.9952 1941715 CBMicro_032217 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccccc3)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K20 compound treatment 0.335 -0.00126 -0.1 0.339 6.56E-4 0.06 -0.0327 -0.2738 1347358 CBMicro_032218 CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(C#N)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K21 compound treatment 0.312 -0.0243 -2.01 0.322 -0.0163 -1.45 -2.4482 -0.9869 1941716 CBMicro_032219 Brc1ccc(OCC(=O)N/N=C/c2ccco2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K22 compound treatment 0.349 0.0127 1.06 0.348 0.00966 0.86 1.3531 0.9945 1662182 CBMicro_032220 Cc1nc(N)sc1c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K23 positive control 0.087 -0.249 -20.69 0.086 -0.252 -22.36 -30.4454 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 K24 positive control 0.091 -0.245 -20.36 0.091 -0.247 -21.92 -29.8973 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L01 mock treatment 0.332 -0.00426 -0.35 0.334 -0.00434 -0.38 -0.5222 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L02 mock treatment 0.345 0.00874 0.73 0.34 0.00166 0.15 0.617 0.8332 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L03 compound treatment 0.324 -0.0123 -1.02 0.321 -0.0173 -1.54 -1.8064 -0.98 1304099 CBMicro_032221 COc1ccc(cc1)C(=O)Nc2cccc(C#C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L04 compound treatment 0.324 -0.0123 -1.02 0.318 -0.0203 -1.8 -1.9944 -0.9634 1941717 CBMicro_032222 CC1=C(C(NC(=S)N1)c2ccccc2F)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L05 compound treatment 0.356 0.0197 1.64 0.359 0.0207 1.83 2.4533 0.9985 1151789 CBMicro_032223 Cc1cc(NC(=O)c2ccc(Cl)cc2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L06 compound treatment 0.332 -0.00426 -0.35 0.328 -0.0103 -0.92 -0.8982 -0.9142 1941718 CBMicro_032224 O=C(CC1S/C(=N\c2ccccc2)/N(C1=O)c3ccccc3)NCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L07 compound treatment 0.479 0.143 11.85 0.486 0.148 13.09 17.6323 0.9988 1941719 CBMicro_032225 NCC(O)CNc1ccc([N+](=O)[O-])c2cccnc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L08 compound treatment 0.333 -0.00326 -0.27 0.338 -3.44E-4 -0.03 -0.2128 -0.7818 1240432 CBMicro_032226 Cc1cc(NC(=O)c2ccc(cc2)C(C)(C)C)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L09 compound treatment 0.326 -0.0103 -0.85 0.328 -0.0103 -0.92 -1.2504 -0.9993 1941720 CBMicro_032227 COc1ccc(CC(=O)NNC(=O)c2ccco2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L10 compound treatment 0.308 -0.0283 -2.35 0.316 -0.0223 -1.98 -3.059 -0.9964 1621162 CBMicro_032228 COC(=O)c1ccc(NC(=O)COc2ccccc2C(C)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L11 compound treatment 0.334 -0.00226 -0.19 0.334 -0.00434 -0.38 -0.4048 -0.9453 1495872 CBMicro_032229 Cc1ccc2nc(oc(=O)c2c1)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L12 compound treatment 0.345 0.00874 0.73 0.344 0.00566 0.5 0.8676 0.9837 1382687 CBMicro_032230 OC(=O)CCC(=O)Nc1ccc(cc1)c2nc3cc4ccccc4cc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L13 compound treatment 0.317 -0.0193 -1.6 0.321 -0.0173 -1.54 -2.2174 -0.9998 1941721 CBMicro_032231 COc1ccc2ccccc2c1C3NC(=S)NC(=C3C(=O)Nc4ccccc4C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L14 compound treatment 0.325 -0.0113 -0.93 0.326 -0.0123 -1.09 -1.4344 -0.9969 1941722 CBMicro_032232 COc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)ccc1OCc4ccccc4Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L15 compound treatment 0.332 -0.00426 -0.35 0.33 -0.00834 -0.74 -0.7728 -0.9429 1941723 CBMicro_032233 [O-][N+](=O)c1cc(cc(c1)c2nc3cc(Cl)ccc3c(=O)o2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L16 compound treatment 0.334 -0.00226 -0.19 0.332 -0.00634 -0.56 -0.5301 -0.8945 1174243 CBMicro_032234 CC(=O)N1CCN(CC(C)(C)NS(=O)(=O)c2ccc(Cl)cc2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L17 compound treatment 0.327 -0.00926 -0.77 0.335 -0.00334 -0.3 -0.753 -0.9141 1941724 CBMicro_032235 CC/C(=C\1/C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2)/N4CCOCC4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L18 compound treatment 0.309 -0.0273 -2.26 0.328 -0.0103 -0.92 -2.2483 -0.9209 1941725 CBMicro_032236 Clc1ccccc1C(=O)NN2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L19 compound treatment 0.361 0.0247 2.05 0.356 0.0177 1.56 2.5589 0.991 1941726 CBMicro_032237 Brc1ccc(o1)C(=O)Nc2ccc(cc2)c3nc4ncccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L20 compound treatment 0.35 0.0137 1.14 0.344 0.00566 0.5 1.1611 0.9318 1157967 CBMicro_032238 Brc1ccc(NC(=O)CC2Nc3ccccc3NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L21 compound treatment 0.329 -0.00726 -0.6 0.333 -0.00534 -0.47 -0.7609 -0.9929 1664368 CBMicro_032239 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2ccc3oc4CCCC(=O)c4c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L22 compound treatment 0.325 -0.0113 -0.93 0.33 -0.00834 -0.74 -1.1837 -0.9933 1782500 CBMicro_032240 Clc1ccc(cc1)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L23 positive control 0.087 -0.249 -20.69 0.086 -0.252 -22.36 -30.4454 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 L24 positive control 0.091 -0.245 -20.36 0.091 -0.247 -21.92 -29.8973 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M01 mock treatment 0.332 -0.00426 -0.35 0.334 -0.00434 -0.38 -0.5222 -0.9991 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M02 mock treatment 0.336 -2.58E-4 -0.02 0.334 -0.00434 -0.38 -0.2874 -0.7453 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M03 compound treatment 0.35 0.0137 1.14 0.349 0.0107 0.94 1.4745 0.9956 1718284 CBMicro_032241 Cc1ccccc1C2(CC2C(=O)Nc3cccc(Cl)c3)c4ccccc4C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M04 compound treatment 0.337 7.42E-4 0.06 0.336 -0.00234 -0.21 -0.1033 -0.4769 1596434 CBMicro_032242 CCOc1ccc(cc1Br)C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M05 compound treatment 0.323 -0.0133 -1.1 0.323 -0.0153 -1.36 -1.7398 -0.9945 1734063 CBMicro_032243 Cc1ccc(cc1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5cccc(C)c5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M06 compound treatment 0.314 -0.0223 -1.85 0.317 -0.0213 -1.89 -2.6441 -0.9999 1941727 CBMicro_032244 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(Br)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M07 compound treatment 0.339 0.00274 0.23 0.34 0.00166 0.15 0.2647 0.9775 1941728 CBMicro_032245 [O-][N+](=O)c1cccc(c1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5ccc(Br)cc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M08 compound treatment 0.332 -0.00426 -0.35 0.341 0.00266 0.24 -0.0835 -0.1966 1941729 CBMicro_032246 COCCOC(=O)c1ccc(NC(=O)COc2ccc(C)c(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M09 compound treatment 0.337 7.42E-4 0.06 0.342 0.00366 0.32 0.2727 0.8267 1941730 CBMicro_032247 N(c1nc(cs1)c2ccncc2)c3ccccn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M10 compound treatment 0.31 -0.0263 -2.18 0.323 -0.0153 -1.36 -2.503 -0.9742 1941731 CBMicro_032248 [O-][N+](=O)c1ccccc1/C=N/NC(=O)COc2ccc3ccccc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M11 compound treatment 0.346 0.00974 0.81 0.34 0.00166 0.15 0.6757 0.822 1941732 CBMicro_032249 COCCOC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M12 compound treatment 0.333 -0.00326 -0.27 0.334 -0.00434 -0.38 -0.4635 -0.9851 1136692 CBMicro_032250 OC(=O)c1ccc(Cl)cc1NC(=O)c2cccs2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M13 compound treatment 0.32 -0.0163 -1.35 0.322 -0.0163 -1.45 -1.9786 -0.9994 1491546 CBMicro_032251 CC(Oc1ccccc1)C(=O)Nc2c(C)cccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M14 compound treatment 0.341 0.00474 0.39 0.337 -0.00134 -0.12 0.1942 0.4721 1240950 CBMicro_032252 O=C(Nc1cccc(c1)c2nc3ccccc3[nH]2)c4cccs4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M15 compound treatment 0.368 0.0317 2.64 0.354 0.0157 1.39 2.8445 0.9551 1362141 CBMicro_032253 O=C(Cc1ccccc1)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M16 compound treatment 0.33 -0.00626 -0.52 0.307 -0.0313 -2.78 -2.3315 -0.8251 1574835 CBMicro_032254 CCOc1ccccc1C(=O)Nc2cc(Cl)ccc2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M17 compound treatment 0.351 0.0147 1.22 0.35 0.0117 1.03 1.5958 0.9964 1290843 CBMicro_032255 COc1cc2nc(oc(=O)c2cc1OC)c3ccc(OC(=O)C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M18 compound treatment 0.297 -0.0393 -3.26 0.297 -0.0413 -3.66 -4.8954 -0.9983 1941733 CBMicro_032256 Oc1ccc(/N=C/2\CSC(=O)N2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M19 compound treatment 0.332 -0.00426 -0.35 0.338 -3.44E-4 -0.03 -0.2715 -0.7652 1331938 CBMicro_032257 CCn1c2ccccc2c3cc(NC(=O)Cc4cccs4)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M20 compound treatment 0.32 -0.0163 -1.35 0.323 -0.0153 -1.36 -1.9159 -1.0 1670030 CBMicro_032258 CCOC(=O)N1CCN(CC1)C(=S)Nc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M21 compound treatment 0.328 -0.00826 -0.69 0.332 -0.00634 -0.56 -0.8823 -0.9951 1459615 CBMicro_032259 COc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccc(Br)cc3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M22 compound treatment 0.332 -0.00426 -0.35 0.333 -0.00534 -0.47 -0.5848 -0.9896 1941734 CBMicro_032260 OC(=O)CCCNS(=O)(=O)c1ccc(NCc2ccccc2)c(c1)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M23 positive control 0.091 -0.245 -20.36 0.086 -0.252 -22.36 -30.2106 -0.9989 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 M24 positive control 0.099 -0.237 -19.7 0.092 -0.246 -21.83 -29.365 -0.9987 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N01 mock treatment 0.34 0.00374 0.31 0.345 0.00666 0.59 0.6368 0.9551 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N02 mock treatment 0.343 0.00674 0.56 0.341 0.00266 0.24 0.5622 0.9259 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N03 compound treatment 0.526 0.19 15.75 0.538 0.2 17.69 23.65 0.9983 1941735 CBMicro_032261 COc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Br)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N04 compound treatment 0.339 0.00274 0.23 0.34 0.00166 0.15 0.2647 0.9775 1941736 CBMicro_032262 OC(=O)c1ccccc1N(CC=C)S(=O)(=O)/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N05 compound treatment 0.329 -0.00726 -0.6 0.33 -0.00834 -0.74 -0.9489 -0.9948 1941737 CBMicro_032263 CN1C(=O)N(C)C(=O)C(=CNc2ccc3CCCc3c2)C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N06 compound treatment 0.349 0.0127 1.06 0.347 0.00866 0.77 1.2904 0.9876 1941738 CBMicro_032264 Cc1cc(ccc1[N+](=O)[O-])N2C(=O)c3ccc(cc3C2=O)S(=O)(=O)c4ccc(cc4)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N07 compound treatment 0.335 -0.00126 -0.1 0.336 -0.00234 -0.21 -0.2207 -0.9494 1184313 CBMicro_032265 COc1ccccc1C(=O)N2CCN(CC2)C=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N08 compound treatment 0.757 0.421 34.93 0.724 0.386 34.18 48.8661 0.9999 1941739 CBMicro_032266 COc1cc(/C=C/2\SC(=S)N(NC(=O)C)C2=O)cc(OC)c1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N09 compound treatment 0.351 0.0147 1.22 0.352 0.0137 1.21 1.7212 1.0 1323115 CBMicro_032267 Cc1cc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4sc(N)nc4C)cc2)no1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N10 compound treatment 0.355 0.0187 1.56 0.34 0.00166 0.15 1.204 0.7704 1467357 CBMicro_032268 Cc1cccc(NCC(O)Cn2c3ccccc3c4ccccc24)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N11 compound treatment 0.333 -0.00326 -0.27 0.329 -0.00934 -0.83 -0.7768 -0.8917 1556147 CBMicro_032269 CCc1ccc(cc1)c2csc(N)n2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N12 compound treatment 0.336 -2.58E-4 -0.02 0.338 -3.44E-4 -0.03 -0.0367 -0.9852 1646335 CBMicro_032270 O=C1N(Cc2cccnc2)C(=O)c3cc(Oc4ccc5C(=O)N(Cc6cccnc6)C(=O)c5c4)ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N13 compound treatment 0.425 0.0887 7.37 0.417 0.0787 6.97 10.1384 0.9996 1782495 CBMicro_032271 Clc1ccc(cc1Cl)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N14 compound treatment 0.34 0.00374 0.31 0.345 0.00666 0.59 0.6368 0.9551 1941740 CBMicro_032272 CSc1sc(I)cc1/C=N/NC(=O)c2nnn(c2C)c3nonc3N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N15 compound treatment 0.473 0.137 11.35 0.506 0.168 14.86 18.5334 0.9912 1941741 CBMicro_032273 COc1ccccc1/C=C/2\SC(=S)N(NC(=O)Cc3ccccc3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N16 compound treatment 0.353 0.0167 1.39 0.356 0.0177 1.56 2.0892 0.9983 1941742 CBMicro_032274 COc1ccccc1NCC(=O)N/N=C\c2c(F)cccc2Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N17 compound treatment 0.383 0.0467 3.88 0.376 0.0377 3.34 5.1036 0.9972 1941743 CBMicro_032275 CCCCCCCSc1n[nH]c(=O)[nH]c1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N18 compound treatment 0.332 -0.00426 -0.35 0.332 -0.00634 -0.56 -0.6475 -0.975 1941744 CBMicro_032276 COc1ccccc1N2C(=O)CC(S/C(=N/c3ccccc3)/NCCc4ccccc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N19 compound treatment 0.341 0.00474 0.39 0.35 0.0117 1.03 1.0088 0.9126 1941745 CBMicro_032277 CN1C(=O)/C(=C/c2ccc(o2)C(=O)C)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N20 compound treatment 0.329 -0.00726 -0.6 0.333 -0.00534 -0.47 -0.7609 -0.9929 1941746 CBMicro_032278 Oc1c(CC=C)cccc1/C=N/NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N21 compound treatment 0.329 -0.00726 -0.6 0.332 -0.00634 -0.56 -0.8236 -0.9994 1179714 CBMicro_032279 Nc1nc2ccc3CCCCc3c2s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N22 compound treatment 0.345 0.00874 0.73 0.346 0.00766 0.68 0.993 0.9994 1269259 CBMicro_032280 COC(=O)C1=C(C)NC(=O)NC1c2ccc(OC(=O)c3cccs3)c(OC)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N23 positive control 0.088 -0.248 -20.61 0.086 -0.252 -22.36 -30.3867 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 N24 positive control 0.092 -0.244 -20.28 0.091 -0.247 -21.92 -29.8386 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O01 mock treatment 0.337 7.42E-4 0.06 0.34 0.00166 0.15 0.1473 0.9256 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O02 mock treatment 0.342 0.00574 0.48 0.341 0.00266 0.24 0.5035 0.9471 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O03 compound treatment 0.334 -0.00226 -0.19 0.333 -0.00534 -0.47 -0.4674 -0.9177 1215420 CBMicro_032281 CC1(CC2c3ccccc3C1c4ccccc24)C(=O)NCc5cccnc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O04 compound treatment 0.331 -0.00526 -0.44 0.331 -0.00734 -0.65 -0.7689 -0.9811 1941747 CBMicro_032282 Fc1cccc(c1)C(=O)NN2C(=O)c3ccccc3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O05 compound treatment 0.328 -0.00826 -0.69 0.328 -0.0103 -0.92 -1.133 -0.9898 1386705 CBMicro_032283 COc1ccc(NC(=O)c2sc3nccc(=O)n3c2C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O06 compound treatment 0.346 0.00974 0.81 0.344 0.00566 0.5 0.9263 0.9735 1941748 CBMicro_032284 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)OCCCc4ccncc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O07 compound treatment 0.333 -0.00326 -0.27 0.332 -0.00634 -0.56 -0.5888 -0.9438 1941749 CBMicro_032285 COc1cccc(c1)N2C(=O)C=C(C)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O08 compound treatment 0.325 -0.0113 -0.93 0.327 -0.0113 -1.01 -1.3717 -0.9993 1334856 CBMicro_032286 OC(=O)c1ccccc1NC(=O)c2ccccc2c3ccccc3C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O09 compound treatment 0.401 0.0647 5.37 0.395 0.0567 5.02 7.3509 0.9994 1251485 CBMicro_032287 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O10 compound treatment 0.324 -0.0123 -1.02 0.323 -0.0153 -1.36 -1.6811 -0.9898 1941750 CBMicro_032288 COc1ccc(cc1)N2C(=O)CC(S/C(=N/c3ccccc3)/NCc4ccc(Cl)cc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O11 compound treatment 0.334 -0.00226 -0.19 0.337 -0.00134 -0.12 -0.2168 -0.976 1941751 CBMicro_032289 COc1ccc(cc1OC)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O12 compound treatment 0.361 0.0247 2.05 0.357 0.0187 1.65 2.6215 0.9942 1268922 CBMicro_032290 CCCOc1ccc(cc1)N2C(=O)CC(N(Cc3ccco3)C(=S)Nc4ccccc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O13 compound treatment 0.335 -0.00126 -0.1 0.335 -0.00334 -0.3 -0.2834 -0.9019 1239877 CBMicro_032291 Clc1ccc2c(=O)oc(nc2c1)c3ccc(Cl)c(Cl)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O14 compound treatment 0.335 -0.00126 -0.1 0.335 -0.00334 -0.3 -0.2834 -0.9019 1559251 CBMicro_032292 Cc1ccc(cc1)S(=O)(=O)NC(C)(C)CN2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O15 compound treatment 0.366 0.0297 2.47 0.369 0.0307 2.72 3.667 0.9989 1509578 CBMicro_032293 COc1cc(cc(OC)c1OC)C(=O)Nc2cccc(c2)c3cc4ccccc4oc3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O16 compound treatment 0.314 -0.0223 -1.85 0.312 -0.0263 -2.33 -2.9575 -0.9933 1941752 CBMicro_032294 N/C(=N\OC(=O)c1ccc(Cl)c(c1)[N+](=O)[O-])/Cc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O17 compound treatment 0.515 0.179 14.84 0.467 0.129 11.4 18.555 0.9915 1941753 CBMicro_032295 NC(=O)/C(=C/c1ccc(o1)c2ccc(Cl)cc2)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O18 compound treatment 0.322 -0.0143 -1.18 0.327 -0.0113 -1.01 -1.5479 -0.9967 1347262 CBMicro_032296 COc1cc2c(cc1NC(=O)CN3C(=O)c4ccccc4C3=O)oc5ccccc52 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O19 compound treatment 0.305 -0.0313 -2.6 0.315 -0.0233 -2.07 -3.2978 -0.9937 1338905 CBMicro_032297 CCC1CCc2c(C(=O)OC(C)C)c(N)sc2C1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O20 compound treatment 0.321 -0.0153 -1.27 0.325 -0.0133 -1.18 -1.7319 -0.9994 1941754 CBMicro_032298 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3c[nH]c4ccccc34)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O21 compound treatment 0.331 -0.00526 -0.44 0.329 -0.00934 -0.83 -0.8942 -0.9553 1941755 CBMicro_032299 CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O22 compound treatment 0.328 -0.00826 -0.69 0.33 -0.00834 -0.74 -1.0076 -0.9993 1941756 CBMicro_032300 CC(CN)(NS(=O)(=O)c1ccccc1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O23 positive control 0.086 -0.25 -20.78 0.086 -0.252 -22.36 -30.5041 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 O24 positive control 0.092 -0.244 -20.28 0.092 -0.246 -21.83 -29.7759 -0.9993 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P01 mock treatment 0.34 0.00374 0.31 0.343 0.00466 0.41 0.5114 0.9902 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P02 mock treatment 0.341 0.00474 0.39 0.342 0.00366 0.32 0.5075 0.9953 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P03 compound treatment 0.347 0.0107 0.89 0.337 -0.00134 -0.12 0.5464 0.6073 1941757 CBMicro_032301 Cc1ccc(/C=C\2/SC(=S)N(NC(=O)c3ccccc3C)C2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P04 compound treatment 0.331 -0.00526 -0.44 0.334 -0.00434 -0.38 -0.5809 -0.998 1339578 CBMicro_032302 CC(C)(C)c1csc(NC(=O)COc2ccc(F)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P05 compound treatment 0.328 -0.00826 -0.69 0.332 -0.00634 -0.56 -0.8823 -0.9951 1941758 CBMicro_032303 Cc1ccc(c(OCC(=O)Nc2ccccc2C(F)(F)F)c1)C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P06 compound treatment 0.328 -0.00826 -0.69 0.324 -0.0143 -1.27 -1.3836 -0.958 1626521 CBMicro_032304 COc1cccc(c1)C(=O)Nc2ccc(c3nc4ccccc4o3)c(O)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P07 compound treatment 0.32 -0.0163 -1.35 0.319 -0.0193 -1.71 -2.1666 -0.993 1609292 CBMicro_032305 Clc1ccccc1C(=O)Nc2cccc(c2)c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P08 compound treatment 0.384 0.0477 3.96 0.386 0.0477 4.22 5.789 0.9995 1146004 CBMicro_032306 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)OCCc5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P09 compound treatment 0.324 -0.0123 -1.02 0.326 -0.0123 -1.09 -1.4931 -0.9993 1662962 CBMicro_032307 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cc(Cl)ccc3C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P10 compound treatment 0.305 -0.0313 -2.6 0.315 -0.0233 -2.07 -3.2978 -0.9937 1780319 CBMicro_032308 [O-][N+](=O)c1cccc(NC(=O)C2COc3ccccc3O2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P11 compound treatment 0.332 -0.00426 -0.35 0.334 -0.00434 -0.38 -0.5222 -0.9991 1434701 CBMicro_032309 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(OC)c(OC)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P12 compound treatment 0.32 -0.0163 -1.35 0.325 -0.0133 -1.18 -1.7906 -0.9978 1522947 CBMicro_032310 O=C(CN1C(=O)c2ccccc2C1=O)Nc3cccc(c3)c4nc5ccccc5c(=O)o4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P13 compound treatment 0.339 0.00274 0.23 0.342 0.00366 0.32 0.3901 0.9851 1267215 CBMicro_032311 CC(C)(C)c1ccc(OCC(=O)Nc2ccc(cc2)C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P14 compound treatment 0.324 -0.0123 -1.02 0.329 -0.00934 -0.83 -1.3051 -0.9948 1941759 CBMicro_032312 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)OCc4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P15 compound treatment 1.088 0.752 62.41 1.113 0.775 68.65 92.6736 0.9989 1941760 CBMicro_032313 CC(N1C(=O)/C(=C/C(=C/c2ccccc2)/C)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P16 compound treatment 0.316 -0.0203 -1.68 0.317 -0.0213 -1.89 -2.5267 -0.9983 1941761 CBMicro_032314 CC1=C(C(NC(=S)N1)c2ccccc2Br)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P17 compound treatment 0.316 -0.0203 -1.68 0.316 -0.0223 -1.98 -2.5894 -0.9967 1941762 CBMicro_032315 C/C(=N\NC(=S)N)/C1=CC(C)(C)CCC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P18 compound treatment 0.326 -0.0103 -0.85 0.326 -0.0123 -1.09 -1.3757 -0.9923 1506481 CBMicro_032316 CCOc1cc(ccc1O)C2NC(=S)NC(=C2C(=O)Nc3ccc(C)cc3)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P19 compound treatment 0.423 0.0867 7.2 0.418 0.0797 7.06 10.0837 1.0 1941763 CBMicro_032317 CC(C)c1ccc(/C=C/2\SC(=S)NC2=O)cc1[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P20 compound treatment 0.339 0.00274 0.23 0.339 6.56E-4 0.06 0.2021 0.8601 1388809 CBMicro_032318 O=C1CC(CC(=C1)NCCN2CCOCC2)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P21 compound treatment 0.33 -0.00626 -0.52 0.333 -0.00534 -0.47 -0.7022 -0.9989 1455122 CBMicro_032319 Cc1cc(NC(=O)c2ccccc2I)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P22 compound treatment 0.326 -0.0103 -0.85 0.329 -0.00934 -0.83 -1.1877 -0.9999 1519586 CBMicro_032320 COc1cc2ccccc2cc1C(=O)Nc3cccc(c3)c4cc5ccccc5oc4=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P23 positive control 0.089 -0.247 -20.53 0.088 -0.25 -22.19 -30.2027 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.786 P24 positive control 0.094 -0.242 -20.11 0.093 -0.245 -21.74 -29.5958 -0.9992 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A01 mock treatment 0.335 -0.00531 -0.44 0.337 -0.00375 -0.33 -0.5469 -0.9903 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A02 mock treatment 0.347 0.00669 0.56 0.356 0.0153 1.35 1.3482 0.9228 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A03 compound treatment 0.346 0.00569 0.47 0.348 0.00725 0.64 0.7882 0.9885 1941764 CBMicro_032321 O=C(COc1ccccc1)NNc2c3ccccc3nc4ccccc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A04 compound treatment 0.363 0.0227 1.88 0.363 0.0222 1.97 2.7261 0.9997 1941765 CBMicro_032322 CCn1c2ccccc2c3cc(NS(=O)(=O)c4cccc(c4)[N+](=O)[O-])ccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A05 compound treatment 0.336 -0.00431 -0.36 0.345 0.00425 0.38 0.0132 0.0253 1373104 CBMicro_032323 Brc1ccc(o1)C(=O)Nc2cccc(c2)c3nc4ncccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A06 compound treatment 0.334 -0.00631 -0.52 0.343 0.00225 0.2 -0.2296 -0.4094 1941766 CBMicro_032324 [O-][N+](=O)c1ccc(cc1)c2nnc(o2)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A07 compound treatment 0.343 0.00269 0.22 0.35 0.00925 0.82 0.7374 0.868 1941767 CBMicro_032325 Ic1ccc(cc1)N2C(=O)CC(NC3CCCCC3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A08 compound treatment 0.346 0.00569 0.47 0.35 0.00925 0.82 0.9135 0.9657 1941768 CBMicro_032326 CC(Oc1ccc(Cl)cc1Cl)C(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A09 compound treatment 0.407 0.0667 5.54 0.395 0.0543 4.81 7.3144 0.9975 1941769 CBMicro_032327 CCCOc1ccc(/C=C/2\SC(=O)N(Cc3ccccc3)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A10 compound treatment 0.468 0.128 10.6 0.482 0.141 12.52 16.3471 0.9966 1941770 CBMicro_032328 C/C(=C\C(=S)Nc1ccccc1)/Nc2ccc(Cl)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A11 compound treatment 0.38 0.0397 3.29 0.368 0.0273 2.41 4.0374 0.9883 1941771 CBMicro_032329 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cccc(c2)c3nc4cc(C)c(C)cc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A12 compound treatment 0.382 0.0417 3.46 0.389 0.0483 4.28 5.4708 0.9945 1941772 CBMicro_032330 COCCOC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A13 compound treatment 0.338 -0.00231 -0.19 0.338 -0.00275 -0.24 -0.3081 -0.993 1194570 CBMicro_032331 CC(=O)N(Cc1ccc2OCOc2c1)C3CC(=O)N(C3=O)c4cccc(Cl)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A14 compound treatment 0.348 0.00769 0.64 0.343 0.00225 0.2 0.5923 0.8858 1941773 CBMicro_032332 CN(C)c1ccc(cc1)C2C(C(=O)C)C(=O)CC(C)(O)C2C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A15 compound treatment 0.364 0.0237 1.97 0.373 0.0323 2.86 3.4115 0.9834 1941774 CBMicro_032333 CC(=O)c1ccc(NC(=O)COc2ccccc2[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A16 compound treatment 0.346 0.00569 0.47 0.347 0.00625 0.55 0.7255 0.9968 1941775 CBMicro_032334 COc1ccc(CCN(C2CC(=O)N(C2=O)c3ccccc3)C(=O)/C=C/C(=O)O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A17 compound treatment 0.748 0.408 33.85 0.72 0.379 33.61 47.6983 1.0 1941776 CBMicro_032335 CC(N1C(=O)/C(=C/c2ccc(cc2)C(=O)O)/SC1=S)C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A18 compound treatment 0.353 0.0127 1.05 0.352 0.0113 1.0 1.4498 0.9996 1941777 CBMicro_032336 COCCOC(=O)c1ccc(NC(=O)COc2ccccc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A19 compound treatment 0.333 -0.00731 -0.61 0.341 2.5E-4 0.02 -0.4136 -0.6808 1941778 CBMicro_032337 CC1=C(C(NC(=S)N1)c2ccc(C)cc2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A20 compound treatment 0.41 0.0697 5.79 0.381 0.0403 3.57 6.6132 0.973 1941779 CBMicro_032338 O=C(CSc1nnnn1c2ccccc2)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A21 compound treatment 0.37 0.0297 2.46 0.359 0.0182 1.62 2.8864 0.9791 1941780 CBMicro_032339 CCCCOc1ccc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A22 compound treatment 0.34 -3.12E-4 -0.03 0.331 -0.00975 -0.86 -0.6293 -0.728 1941781 CBMicro_032340 COc1ccc(cc1)C2=N/C(=C/c3ccc(Br)cc3)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A23 positive control 0.083 -0.257 -21.36 0.087 -0.254 -22.49 -31.0064 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 A24 positive control 0.085 -0.255 -21.2 0.089 -0.252 -22.31 -30.7636 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B01 mock treatment 0.334 -0.00631 -0.52 0.331 -0.00975 -0.86 -0.9815 -0.9713 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B02 mock treatment 0.342 0.00169 0.14 0.34 -7.5E-4 -0.07 0.0521 0.3358 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B03 compound treatment 0.341 6.88E-4 0.06 0.34 -7.5E-4 -0.07 -0.0066 -0.0758 1147269 CBMicro_032341 Clc1ccc(cc1Cl)C(=O)Nc2c[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B04 compound treatment 0.344 0.00369 0.31 0.344 0.00325 0.29 0.4201 0.9995 1292291 CBMicro_032342 COc1ccc(CN2CCN(CC2)C(=O)c3ccccc3OC)cc1OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B05 compound treatment 0.339 -0.00131 -0.11 0.348 0.00725 0.64 0.3773 0.5789 1941782 CBMicro_032343 CCCOc1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccccc3Cl)C2=O)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B06 compound treatment 0.338 -0.00231 -0.19 0.335 -0.00575 -0.51 -0.4961 -0.911 1941783 CBMicro_032344 Clc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)nc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B07 compound treatment 0.34 -3.12E-4 -0.03 0.333 -0.00775 -0.69 -0.504 -0.7333 1367581 CBMicro_032345 CCCC(=O)Nc1ccc2OCCOc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B08 compound treatment 0.363 0.0227 1.88 0.361 0.0203 1.79 2.6008 0.9997 1941784 CBMicro_032346 CCC(C)c1ccc(OCCOc2ccc(Cl)cc2/C=N/n3cnnc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B09 compound treatment 0.335 -0.00531 -0.44 0.335 -0.00575 -0.51 -0.6722 -0.9974 1451756 CBMicro_032347 COc1ccc(cc1CO)C(C2=C(O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B10 compound treatment 0.338 -0.00231 -0.19 0.339 -0.00175 -0.16 -0.2454 -0.9944 1941785 CBMicro_032348 COc1cccc(/C=N/NC(=O)CSCC(=O)Nc2ccccc2)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B11 compound treatment 0.388 0.0477 3.96 0.383 0.0423 3.74 5.447 0.9996 1941786 CBMicro_032349 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3ccc(OCc4ccccc4)c(OC)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B12 compound treatment 0.369 0.0287 2.38 0.366 0.0253 2.24 3.2663 0.9995 1208965 CBMicro_032350 COC(=O)c1cc(Cl)c(NC(=O)c2ccccc2CCc3ccccc3)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B13 compound treatment 0.349 0.00869 0.72 0.357 0.0163 1.44 1.5283 0.9489 1941787 CBMicro_032351 CC(C)(C)c1csc(N/N=C/c2ccc(O)cc2)n1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B14 compound treatment 0.355 0.0147 1.22 0.356 0.0153 1.35 1.8178 0.9987 1941788 CBMicro_032352 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B15 compound treatment 0.339 -0.00131 -0.11 0.335 -0.00575 -0.51 -0.4374 -0.8393 1464783 CBMicro_032353 COc1ccc(CN2CCN(CC2)C(=O)c3ccco3)cc1OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B16 compound treatment 0.341 6.88E-4 0.06 0.341 2.5E-4 0.02 0.056 0.9151 1941789 CBMicro_032354 CN1C(=O)NC(=O)/C(=C/c2ccc(O)c(Br)c2)/C1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B17 compound treatment 0.337 -0.00331 -0.28 0.347 0.00625 0.55 0.1972 0.3189 1941790 CBMicro_032355 Cc1ccc(NC(=O)/C(=C\c2ccccc2)/NC(=O)c3ccccc3I)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B18 compound treatment 0.348 0.00769 0.64 0.352 0.0113 1.0 1.1563 0.9768 1941791 CBMicro_032356 [O-][N+](=O)c1ccc(/C=C/C(=O)c2ccc(I)cc2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B19 compound treatment 0.334 -0.00631 -0.52 0.335 -0.00575 -0.51 -0.7309 -0.9999 1787317 CBMicro_032357 CCOc1ccc(CN2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-])cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B20 compound treatment 0.369 0.0287 2.38 0.364 0.0233 2.06 3.141 0.9974 1125509 CBMicro_032358 CC(C)COC(=O)c1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B21 compound treatment 0.331 -0.00931 -0.77 0.335 -0.00575 -0.51 -0.907 -0.9795 1427151 CBMicro_032359 C(N1CCC(CC1)N2CCN(CC2)C3CCC(CC3)c4ccccc4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B22 compound treatment 0.374 0.0337 2.8 0.331 -0.00975 -0.86 1.3666 0.4669 1334289 CBMicro_032360 CC(C)c1ccccc1NC(=O)COc2ccc(Cl)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B23 positive control 0.083 -0.257 -21.36 0.085 -0.256 -22.67 -31.1317 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 B24 positive control 0.084 -0.256 -21.28 0.088 -0.253 -22.4 -30.885 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C01 mock treatment 0.342 0.00169 0.14 0.337 -0.00375 -0.33 -0.1359 -0.3769 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C02 mock treatment 0.354 0.0137 1.14 0.343 0.00225 0.2 0.9445 0.8187 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C03 compound treatment 0.323 -0.0173 -1.44 0.34 -7.5E-4 -0.07 -1.0633 -0.739 1941792 CBMicro_032361 COc1ccc(cc1)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C04 compound treatment 0.341 6.88E-4 0.06 0.345 0.00425 0.38 0.3067 0.8051 1941793 CBMicro_032362 CSc1ccc(/C=N\NC(=O)C2COc3cc4ccccc4cc3O2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C05 compound treatment 0.344 0.00369 0.31 0.344 0.00325 0.29 0.4201 0.9995 1941794 CBMicro_032363 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(O)c(c2)c3nc4cc(C)c(C)cc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C06 compound treatment 0.339 -0.00131 -0.11 0.317 -0.0238 -2.1 -1.5653 -0.7427 1460051 CBMicro_032364 Cc1c(Br)c(=O)[nH]c(=O)n1Cc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C07 compound treatment 0.339 -0.00131 -0.11 0.338 -0.00275 -0.24 -0.2494 -0.9341 1941795 CBMicro_032365 [O-][N+](=O)c1ccc(cc1)C(=O)/C=C/c2ccc(o2)c3cc(Cl)ccc3Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C08 compound treatment 0.342 0.00169 0.14 0.342 0.00125 0.11 0.1774 0.9932 1941796 CBMicro_032366 OCCNC(=O)/C(=C\c1cccs1)/NC(=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C09 compound treatment 0.344 0.00369 0.31 0.343 0.00225 0.2 0.3575 0.9784 1287190 CBMicro_032367 COC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)cc2OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C10 compound treatment 0.348 0.00769 0.64 0.344 0.00325 0.29 0.6549 0.9354 1226705 CBMicro_032368 CCOC(=O)c1sc(NC(=O)c2c(C)onc2c3ccccc3Cl)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C11 compound treatment 0.337 -0.00331 -0.28 0.34 -7.5E-4 -0.07 -0.2415 -0.8534 1941797 CBMicro_032369 CC(CCC=C(C)C)NCc1ccco1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C12 compound treatment 0.347 0.00669 0.56 0.348 0.00725 0.64 0.8469 0.9974 1941798 CBMicro_032370 Oc1cc(/C=N\NC(=O)C2C(CNC2=O)c3ccccc3)c(Br)cc1Br 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C13 compound treatment 0.337 -0.00331 -0.28 0.332 -0.00875 -0.78 -0.7428 -0.9028 1465362 CBMicro_032371 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C14 compound treatment 0.341 6.88E-4 0.06 0.335 -0.00575 -0.51 -0.32 -0.624 1014352 CBMicro_032372 OC(Cc1ccc2ccccc2n1)C(Cl)(Cl)Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C15 compound treatment 0.38 0.0397 3.29 0.384 0.0432 3.83 5.0401 0.9972 1347031 CBMicro_032373 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Cl)cc3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C16 compound treatment 0.354 0.0137 1.14 0.363 0.0222 1.97 2.1978 0.9657 1941799 CBMicro_032374 CCN1C(=O)/C(=C\c2cc(Cl)ccc2O)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C17 compound treatment 0.433 0.0927 7.69 0.439 0.0983 8.71 11.5979 0.9981 1941800 CBMicro_032375 COC(=O)/C(=C/c1ccc(o1)c2ccc(cc2)S(=O)(=O)N)/C#N 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C18 compound treatment 0.348 0.00769 0.64 0.349 0.00825 0.73 0.9683 0.9977 1941801 CBMicro_032376 COCCOC(=O)c1ccc(NC(=O)C(C)Oc2ccc(Cl)cc2C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C19 compound treatment 0.358 0.0177 1.47 0.376 0.0352 3.12 3.2473 0.9407 1716269 CBMicro_032377 CCCc1cc(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C20 compound treatment 0.376 0.0357 2.96 0.359 0.0182 1.62 3.2386 0.9595 1941802 CBMicro_032378 CC(=O)c1cc(sc1Nc2ccccc2)C(=O)CC(=O)Nc3cccc(c3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C21 compound treatment 0.33 -0.0103 -0.86 0.33 -0.0107 -0.95 -1.279 -0.9986 1158287 CBMicro_032379 Cc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C22 compound treatment 0.337 -0.00331 -0.28 0.33 -0.0107 -0.95 -0.8681 -0.8755 1156788 CBMicro_032380 CC1CCN(CC1)C(=O)CSc2nc3ccccc3[nH]2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C23 positive control 0.081 -0.259 -21.53 0.086 -0.255 -22.58 -31.1864 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 C24 positive control 0.085 -0.255 -21.2 0.09 -0.251 -22.22 -30.701 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D01 mock treatment 0.339 -0.00131 -0.11 0.344 0.00325 0.29 0.1266 0.4112 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D02 mock treatment 0.346 0.00569 0.47 0.343 0.00225 0.2 0.4749 0.9265 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D03 compound treatment 0.371 0.0307 2.55 0.374 0.0333 2.95 3.8851 0.9974 1941803 CBMicro_032381 COc1ccc(cc1)N2C(=O)S/C(=C\c3ccc(O)c(OC)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D04 compound treatment 0.326 -0.0143 -1.19 0.339 -0.00175 -0.16 -0.9499 -0.7927 1941804 CBMicro_032382 CN(C)CCN1C(C(=C(O)C1=O)C(=O)C)c2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D05 compound treatment 0.349 0.00869 0.72 0.35 0.00925 0.82 1.0896 0.998 1597049 CBMicro_032383 CCOc1ccc2cc(ccc2c1)S(=O)(=O)N3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D06 compound treatment 0.337 -0.00331 -0.28 0.339 -0.00175 -0.16 -0.3041 -0.9633 1145154 CBMicro_032384 Clc1ccccc1OCC(=O)NCc2ccco2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D07 compound treatment 0.342 0.00169 0.14 0.346 0.00525 0.47 0.4281 0.881 1941805 CBMicro_032385 CCC1CCCCN1S(=O)(=O)c2ccc(C)c(C)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D08 compound treatment 0.355 0.0147 1.22 0.349 0.00825 0.73 1.3792 0.9701 1941806 CBMicro_032386 COc1cc(/C=N/n2cnnc2)ccc1OCCOc3ccccc3CC=C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D09 compound treatment 0.342 0.00169 0.14 0.337 -0.00375 -0.33 -0.1359 -0.3769 1941807 CBMicro_032387 Cc1onc(c1C(=O)NCCCN2CCN(CCCNC(=O)c3c(C)onc3c4ccccc4)CC2)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D10 compound treatment 0.345 0.00469 0.39 0.342 0.00125 0.11 0.3535 0.8737 1677107 CBMicro_032388 C(Sc1nnnn1c2ccccc2)c3cccc(CSc4nnnn4c5ccccc5)n3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D11 compound treatment 0.422 0.0817 6.78 0.437 0.0963 8.53 10.8268 0.9935 1941808 CBMicro_032389 [O-][N+](=O)c1cccc(N/C=C/2\N=C(OC2=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D12 compound treatment 0.341 6.88E-4 0.06 0.348 0.00725 0.64 0.4947 0.7669 1941809 CBMicro_032390 Cc1ccc(cc1)S(=O)(=O)/N=C\2/C=C(C(=O)c3ccccc23)S(=O)(=O)c4ccc(C)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D13 compound treatment 0.339 -0.00131 -0.11 0.354 0.0133 1.17 0.7533 0.6387 1941810 CBMicro_032391 COc1ccc(NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D14 compound treatment 0.359 0.0187 1.55 0.349 0.00825 0.73 1.614 0.9411 1941811 CBMicro_032392 CC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(Br)cc2)C(=O)C)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D15 compound treatment 0.338 -0.00231 -0.19 0.336 -0.00475 -0.42 -0.4334 -0.9368 1787302 CBMicro_032393 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(CC3CC4CC3C=C4)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D16 compound treatment 0.342 0.00169 0.14 0.348 0.00725 0.64 0.5534 0.8415 1941812 CBMicro_032394 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C)C2=O)cc(I)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D17 compound treatment 0.341 6.88E-4 0.06 0.338 -0.00275 -0.24 -0.132 -0.5272 1941813 CBMicro_032395 OC(=O)/C(=C\c1ccccc1)/NC(=O)c2ccccc2I 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D18 compound treatment 0.342 0.00169 0.14 0.338 -0.00275 -0.24 -0.0733 -0.2606 1471597 CBMicro_032396 Clc1ccccc1CN2CCN(CC2)C3CCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D19 compound treatment 0.34 -3.12E-4 -0.03 0.348 0.00725 0.64 0.436 0.678 1941814 CBMicro_032397 [O-][N+](=O)c1cccc(CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D20 compound treatment 0.352 0.0117 0.97 0.353 0.0123 1.09 1.4537 0.9984 1941815 CBMicro_032398 COc1ccc(NC(=O)COc2cccc(Cl)c2)c(c1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D21 compound treatment 0.336 -0.00431 -0.36 0.334 -0.00675 -0.6 -0.6761 -0.9699 1424447 CBMicro_032399 COc1ccc(CN2CCN(CC2)C3CCCCC3)cc1OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D22 compound treatment 0.34 -3.12E-4 -0.03 0.345 0.00425 0.38 0.248 0.6568 1348612 CBMicro_032400 Clc1cccc(OCC(=O)Nc2nccs2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D23 positive control 0.083 -0.257 -21.36 0.088 -0.253 -22.4 -30.9437 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 D24 positive control 0.088 -0.252 -20.95 0.095 -0.246 -21.78 -30.2115 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E01 mock treatment 0.331 -0.00931 -0.77 0.331 -0.00975 -0.86 -1.1577 -0.9985 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E02 mock treatment 0.346 0.00569 0.47 0.342 0.00125 0.11 0.4122 0.8499 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E03 compound treatment 0.343 0.00269 0.22 0.347 0.00625 0.55 0.5494 0.9201 1941816 CBMicro_032401 Cc1ccc(/C=N/NC(=O)CSc2nc3ccccc3[nH]2)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E04 compound treatment 0.173 -0.167 -13.89 0.188 -0.153 -13.54 -19.3939 -0.9999 1941817 CBMicro_032402 Brc1ccc(cc1)c2ccc(/C=C\3/SC(=S)NC3=S)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E05 compound treatment 0.328 -0.0123 -1.02 0.338 -0.00275 -0.24 -0.8951 -0.8518 1258077 CBMicro_032403 Oc1ccc(NC2=CC(=O)CC(C2)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E06 compound treatment 0.49 0.15 12.43 0.504 0.163 14.47 19.0172 0.9971 1941818 CBMicro_032404 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)cc(Cl)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E07 compound treatment 0.34 -3.12E-4 -0.03 0.34 -7.5E-4 -0.07 -0.0653 -0.9158 1941819 CBMicro_032405 OC(=O)CCC(=O)N(CCc1ccccc1)C2CC(=O)N(C2=O)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E08 compound treatment 0.338 -0.00231 -0.19 0.349 0.00825 0.73 0.3812 0.5043 1532318 CBMicro_032406 COc1ccc2oc(=O)c(cc2c1)C(=O)NC3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E09 compound treatment 0.346 0.00569 0.47 0.343 0.00225 0.2 0.4749 0.9265 1695743 CBMicro_032407 COc1ccc(CCN(C2CC(=O)N(C2=O)c3ccccc3)C(=O)C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E10 compound treatment 0.345 0.00469 0.39 0.347 0.00625 0.55 0.6668 0.9851 1941820 CBMicro_032408 Cc1cc([N+](=O)[O-])c(C)c(c1)c2ccc(C=c3sc4nc5cc(Br)cnc5n4c3=O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E11 compound treatment 0.329 -0.0113 -0.94 0.337 -0.00375 -0.33 -0.8991 -0.9025 1941821 CBMicro_032409 CC1=C(C(NC(=S)N1)c2cccs2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E12 compound treatment 0.329 -0.0113 -0.94 0.342 0.00125 0.11 -0.5857 -0.6194 1032026 CBMicro_032410 O=C1NC(=O)C(=Cc2ccccc2)C(=O)N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E13 compound treatment 0.405 0.0647 5.37 0.445 0.104 9.24 10.3302 0.9667 1941822 CBMicro_032411 CCOc1cc(/C=C/2\SC(=S)N(C2=O)c3cccc(C)c3C)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E14 compound treatment 0.342 0.00169 0.14 0.337 -0.00375 -0.33 -0.1359 -0.3769 1374073 CBMicro_032412 CCOC(=O)C1C(C(=O)OCC)C2(CCCCC2)OC1=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E15 compound treatment 0.341 6.88E-4 0.06 0.337 -0.00375 -0.33 -0.1946 -0.5772 1941823 CBMicro_032413 CCOc1cccc(c1)N2C(=O)CC(N3CCN(C)CC3)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E16 compound treatment 0.34 -3.12E-4 -0.03 0.335 -0.00575 -0.51 -0.3787 -0.7421 1720199 CBMicro_032414 Cc1cc2nc3sc(=Cc4ccc5OCOc5c4)c(=O)n3c2cc1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E17 compound treatment 0.343 0.00269 0.22 0.343 0.00225 0.2 0.2988 0.9984 1941824 CBMicro_032415 CC1CCCN(C1)C(=O)c2sc3cc(ccc3c2Cl)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E18 compound treatment 0.345 0.00469 0.39 0.341 2.5E-4 0.02 0.2908 0.7462 1941825 CBMicro_032416 O=c1[nH]c(N/N=C/C2CCC=CC2)nnc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E19 compound treatment 0.397 0.0567 4.71 0.349 0.00825 0.73 3.8447 0.8073 1202099 CBMicro_032417 O=C1Nc2c(cc(c3cccc1c23)S(=O)(=O)N4CCOCC4)S(=O)(=O)N5CCOCC5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E20 compound treatment 0.341 6.88E-4 0.06 0.334 -0.00675 -0.6 -0.3826 -0.6367 1601334 CBMicro_032418 CC(Sc1n[nH]c(=O)[nH]c1=O)C(=O)OCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E21 compound treatment 0.345 0.00469 0.39 0.342 0.00125 0.11 0.3535 0.8737 1389129 CBMicro_032419 CC(C)(C)NC(=O)c1cccc(NC(=O)c2cccs2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E22 compound treatment 0.484 0.144 11.93 0.476 0.135 11.99 16.9104 1.0 1941826 CBMicro_032420 Cc1ccc(cc1C)N2NC(=O)/C(=C/c3ccc(O)c(O)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E23 positive control 0.08 -0.26 -21.61 0.087 -0.254 -22.49 -31.1825 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 E24 positive control 0.09 -0.25 -20.78 0.096 -0.245 -21.69 -30.0315 -0.9998 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F01 mock treatment 0.335 -0.00531 -0.44 0.336 -0.00475 -0.42 -0.6095 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F02 mock treatment 0.341 6.88E-4 0.06 0.342 0.00125 0.11 0.1187 0.9524 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F03 compound treatment 0.353 0.0127 1.05 0.353 0.0123 1.09 1.5124 0.9999 1366425 CBMicro_032421 CC(=C)CN1CCN(CC1)S(=O)(=O)c2ccc-3c(Cc4cc(ccc43)S(=O)(=O)N5CCN(CC(=C)C)CC5)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F04 compound treatment 0.35 0.00969 0.8 0.35 0.00925 0.82 1.1483 1.0 1553176 CBMicro_032422 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCCC(=O)O)C2c3ccc4OCOc4c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F05 compound treatment 0.343 0.00269 0.22 0.341 2.5E-4 0.02 0.1734 0.7735 1083609 CBMicro_032423 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=S)N2CCOCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F06 compound treatment 0.361 0.0207 1.72 0.379 0.0382 3.39 3.6114 0.9503 1252498 CBMicro_032424 CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc3COC(C)(CC)Cc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F07 compound treatment 0.34 -3.12E-4 -0.03 0.336 -0.00475 -0.42 -0.316 -0.7493 1941827 CBMicro_032425 CN(C)/C(=N\S(=O)(=O)c1ccc(Br)cc1)/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F08 compound treatment 0.339 -0.00131 -0.11 0.347 0.00625 0.55 0.3146 0.5573 1213555 CBMicro_032426 CNc1ccc2[nH]nc3-c4ccccc4C(=O)c1c32 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F09 compound treatment 0.334 -0.00631 -0.52 0.339 -0.00175 -0.16 -0.4802 -0.8787 1121202 CBMicro_032427 OC1=C(C(C2=C(O)CC(CC2=O)c3ccccc3)c4ccc(O)c(O)c4)C(=O)CC(C1)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F10 compound treatment 0.75 0.41 34.01 0.761 0.42 37.24 50.385 0.999 1941828 CBMicro_032428 Brc1ccc(N/N=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F11 compound treatment 0.373 0.0327 2.71 0.385 0.0442 3.92 4.6918 0.9838 1688401 CBMicro_032429 Cc1ccccc1NC(=O)c2c(NC(=O)c3cccc(Cl)c3)sc4CCCCc24 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F12 compound treatment 0.321 -0.0193 -1.6 0.319 -0.0217 -1.93 -2.4967 -0.9958 1941829 CBMicro_032430 Cc1ccc(cc1)S(=O)(=O)/N=C/2\C=C(C(=O)c3ccccc23)n4cnc5ccccc45 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F13 compound treatment 0.408 0.0677 5.62 0.409 0.0683 6.05 8.2504 0.9993 1941830 CBMicro_032431 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3ccccc3)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F14 compound treatment 0.359 0.0187 1.55 0.359 0.0182 1.62 2.2407 0.9998 1941831 CBMicro_032432 OC1=C(C(N(C1=O)c2cccc(Br)c2)c3ccccc3[N+](=O)[O-])C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F15 compound treatment 0.374 0.0337 2.8 0.362 0.0213 1.88 3.3092 0.9815 1309132 CBMicro_032433 COc1ccccc1C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(Br)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F16 compound treatment 0.336 -0.00431 -0.36 0.34 -7.5E-4 -0.07 -0.3002 -0.8243 1631330 CBMicro_032434 CCC(CC)N1CCN(Cc2cc(Br)ccc2OC)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F17 compound treatment 0.339 -0.00131 -0.11 0.336 -0.00475 -0.42 -0.3747 -0.8617 1589585 CBMicro_032435 Brc1ccc(CN2CCN(CC2)C3CCCCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F18 compound treatment 0.391 0.0507 4.21 0.362 0.0213 1.88 4.3072 0.9343 1564811 CBMicro_032436 COc1ccc(cc1)C2C(C(=O)c3ccccc3)C(=O)CC(C)(O)C2C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F19 compound treatment 0.335 -0.00531 -0.44 0.338 -0.00275 -0.24 -0.4842 -0.9609 1153975 CBMicro_032437 O=C(N1CCN(CCCc2ccccc2)CC1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F20 compound treatment 0.328 -0.0123 -1.02 0.34 -7.5E-4 -0.07 -0.7698 -0.7515 1941832 CBMicro_032438 CCCCOC(=O)c1cccc(NC(=O)COc2ccccc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F21 compound treatment 0.334 -0.00631 -0.52 0.335 -0.00575 -0.51 -0.7309 -0.9999 1210360 CBMicro_032439 C(CN1CCN(CC1)C2CCCCC2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F22 compound treatment 0.348 0.00769 0.64 0.341 2.5E-4 0.02 0.4669 0.7312 1336591 CBMicro_032440 Clc1ccc(NC(=O)COc2ccccc2)c(c1)C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F23 positive control 0.087 -0.253 -21.03 0.091 -0.25 -22.13 -30.5209 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 F24 positive control 0.089 -0.251 -20.86 0.093 -0.248 -21.96 -30.2781 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G01 mock treatment 0.328 -0.0123 -1.02 0.336 -0.00475 -0.42 -1.0204 -0.9231 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G02 mock treatment 0.335 -0.00531 -0.44 0.335 -0.00575 -0.51 -0.6722 -0.9974 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G03 compound treatment 0.371 0.0307 2.55 0.375 0.0343 3.04 3.9477 0.9962 1941833 CBMicro_032441 CCOc1ccc(/C=C\2/NC(=S)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G04 compound treatment 0.348 0.00769 0.64 0.356 0.0153 1.35 1.4069 0.9413 1490219 CBMicro_032442 COc1cccc(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G05 compound treatment 0.382 0.0417 3.46 0.382 0.0413 3.66 5.0321 0.9996 1941834 CBMicro_032443 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(cc3)C(=O)O)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G06 compound treatment 0.355 0.0147 1.22 0.361 0.0203 1.79 2.1312 0.9823 1165256 CBMicro_032444 NC(=O)c1c(NC(=O)c2ccccc2Cl)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G07 compound treatment 0.343 0.00269 0.22 0.338 -0.00275 -0.24 -0.0146 -0.0441 1941835 CBMicro_032445 [O-][N+](=O)c1cccc(c1)C(=O)Nc2ccc(cc2)c3nc4ccccc4c(=O)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G08 compound treatment 0.336 -0.00431 -0.36 0.336 -0.00475 -0.42 -0.5508 -0.9968 1941836 CBMicro_032446 CN1CCN(CC1)C(=O)/C(=C\c2cccs2)/NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G09 compound treatment 0.357 0.0167 1.39 0.355 0.0143 1.26 1.8726 0.9989 1292664 CBMicro_032447 COc1ccc(NC2CC(=O)N(C2=O)c3ccccc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G10 compound treatment 0.323 -0.0173 -1.44 0.335 -0.00575 -0.51 -1.3766 -0.9027 1941837 CBMicro_032448 OC(C(=O)NCCCCOc1ccccc1)(c2ccc(F)cc2)c3ccc(F)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G11 compound treatment 0.383 0.0427 3.54 0.376 0.0352 3.12 4.7148 0.998 1941838 CBMicro_032449 Fc1cccc(Cl)c1/C=N/Nc2nc3ccccc3s2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G12 compound treatment 0.651 0.311 25.79 0.622 0.281 24.92 35.8629 0.9999 1941839 CBMicro_032450 Clc1ccc(/C=C\2/SC(=S)NC2=O)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G13 compound treatment 0.343 0.00269 0.22 0.35 0.00925 0.82 0.7374 0.868 1941840 CBMicro_032451 CC1=C(C(NC(=S)N1)c2ccc(C)cc2)C(=O)Nc3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G14 compound treatment 0.349 0.00869 0.72 0.346 0.00525 0.47 0.839 0.9775 1941841 CBMicro_032452 Clc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G15 compound treatment 0.385 0.0447 3.71 0.393 0.0522 4.63 5.8976 0.994 1439761 CBMicro_032453 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccccc4Br)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G16 compound treatment 0.364 0.0237 1.97 0.365 0.0243 2.15 2.9102 0.999 1941842 CBMicro_032454 CC1=NN(C(=O)C1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4O)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G17 compound treatment 0.345 0.00469 0.39 0.347 0.00625 0.55 0.6668 0.9851 1941843 CBMicro_032455 COc1cc(/C=N\NC(=O)COc2ccccc2Cl)cc(OC)c1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G18 compound treatment 0.378 0.0377 3.13 0.367 0.0262 2.33 3.8573 0.9894 1941844 CBMicro_032456 [O-][N+](=O)c1ccc(Cl)cc1NCc2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G19 compound treatment 0.329 -0.0113 -0.94 0.332 -0.00875 -0.78 -1.2124 -0.9955 1941845 CBMicro_032457 Fc1ccc(/C=N/N2CCOCC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G20 compound treatment 0.359 0.0187 1.55 0.355 0.0143 1.26 1.99 0.9948 1941846 CBMicro_032458 CC(=O)c1cc(sc1Nc2ccccc2)C(=O)CC(=O)Nc3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G21 compound treatment 0.379 0.0387 3.21 0.386 0.0452 4.01 5.1067 0.9939 1551896 CBMicro_032459 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccccc4I)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G22 compound treatment 0.33 -0.0103 -0.86 0.331 -0.00975 -0.86 -1.2164 -1.0 1941847 CBMicro_032460 CN1C(=O)/C(=C\C=C\c2ccc(Br)cc2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G23 positive control 0.086 -0.254 -21.11 0.089 -0.252 -22.31 -30.7049 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 G24 positive control 0.092 -0.248 -20.61 0.095 -0.246 -21.78 -29.9767 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H01 mock treatment 0.333 -0.00731 -0.61 0.336 -0.00475 -0.42 -0.7269 -0.984 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H02 mock treatment 0.34 -3.12E-4 -0.03 0.333 -0.00775 -0.69 -0.504 -0.7333 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H03 compound treatment 0.358 0.0177 1.47 0.365 0.0243 2.15 2.5579 0.9828 1941848 CBMicro_032461 CCOc1cc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)ccc1OCc4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H04 compound treatment 0.341 6.88E-4 0.06 0.337 -0.00375 -0.33 -0.1946 -0.5772 1239151 CBMicro_032462 Fc1cccc(c1)C(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H05 compound treatment 0.348 0.00769 0.64 0.345 0.00425 0.38 0.7176 0.9684 1728061 CBMicro_032463 OCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cccc(F)c3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H06 compound treatment 0.367 0.0267 2.22 0.353 0.0123 1.09 2.3343 0.9461 1941849 CBMicro_032464 CC1(C)Cc2c(CO1)sc3[nH]c(=S)[nH]c(=S)c23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H07 compound treatment 0.361 0.0207 1.72 0.344 0.00325 0.29 1.4181 0.8143 1941850 CBMicro_032465 O/C(=C(/C#N)\c1nc2ccccc2s1)/C(c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H08 compound treatment 0.336 -0.00431 -0.36 0.334 -0.00675 -0.6 -0.6761 -0.9699 1309282 CBMicro_032466 COc1ccc(CN(C2CC(C)N(C)CC2C)C(=O)c3ccco3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H09 compound treatment 0.346 0.00569 0.47 0.359 0.0182 1.62 1.4775 0.8769 1439803 CBMicro_032467 COc1ccc(OC)c(NC(=O)COc2ccccc2C(C)(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H10 compound treatment 0.349 0.00869 0.72 0.348 0.00725 0.64 0.9643 0.9983 1211161 CBMicro_032468 Nc1nnc(SCC(=O)NC(c2ccccc2)c3ccccc3)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H11 compound treatment 0.328 -0.0123 -1.02 0.331 -0.00975 -0.86 -1.3338 -0.9965 1941851 CBMicro_032469 FC(F)(F)C(F)(F)C1=CC(=O)Nc2ccccc2N1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H12 compound treatment 0.334 -0.00631 -0.52 0.325 -0.0158 -1.4 -1.3575 -0.9105 1687562 CBMicro_032470 COC(=O)c1cc(Cl)c(NC(=O)COc2cc(C)ccc2C(C)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H13 compound treatment 0.336 -0.00431 -0.36 0.352 0.0113 1.0 0.4518 0.4265 1593332 CBMicro_032471 Cc1ccccc1CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H14 compound treatment 0.368 0.0277 2.3 0.366 0.0253 2.24 3.2076 0.9999 1210141 CBMicro_032472 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(Br)c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H15 compound treatment 0.348 0.00769 0.64 0.355 0.0143 1.26 1.3443 0.95 1941852 CBMicro_032473 CC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(Br)cc2)C(=O)C)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H16 compound treatment 0.323 -0.0173 -1.44 0.33 -0.0107 -0.95 -1.69 -0.9801 1263175 CBMicro_032474 COc1ccc(CN2CCN(CC2)C3CCC(CC3)c4ccccc4)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H17 compound treatment 0.365 0.0247 2.05 0.366 0.0253 2.24 3.0315 0.999 1236011 CBMicro_032475 OC1=C(C(N(C1=O)c2cccnc2)c3ccc(Br)cc3)C(=O)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H18 compound treatment 0.336 -0.00431 -0.36 0.33 -0.0107 -0.95 -0.9268 -0.9107 1941853 CBMicro_032476 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H19 compound treatment 0.324 -0.0163 -1.35 0.326 -0.0147 -1.31 -1.8819 -0.9998 1941854 CBMicro_032477 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H20 compound treatment 0.335 -0.00531 -0.44 0.358 0.0173 1.53 0.7691 0.4834 1941855 CBMicro_032478 CCCCOC(=O)c1cccc(NC(=O)COc2ccccc2Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H21 compound treatment 0.339 -0.00131 -0.11 0.334 -0.00675 -0.6 -0.5 -0.8224 1376267 CBMicro_032479 Clc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C3CCCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H22 compound treatment 0.341 6.88E-4 0.06 0.339 -0.00175 -0.16 -0.0693 -0.4194 1392993 CBMicro_032480 CCc1ccc(NC(=O)COc2ccc(C)c(C)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H23 positive control 0.087 -0.253 -21.03 0.089 -0.252 -22.31 -30.6462 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 H24 positive control 0.094 -0.246 -20.45 0.096 -0.245 -21.69 -29.7966 -0.9996 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I01 mock treatment 0.341 6.88E-4 0.06 0.345 0.00425 0.38 0.3067 0.8051 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I02 mock treatment 0.348 0.00769 0.64 0.344 0.00325 0.29 0.6549 0.9354 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I03 compound treatment 0.352 0.0117 0.97 0.354 0.0133 1.17 1.5164 0.9955 1941856 CBMicro_032481 CCOC(=O)c1c(C)c(sc1NC(=O)COc2cc(C)ccc2C(C)(C)C)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I04 compound treatment 0.423 0.0827 6.86 0.404 0.0633 5.61 8.8176 0.9949 1941857 CBMicro_032482 CCc1cccc2/C(=C\3/SC(=S)NC3=O)/C(=O)Nc21 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I05 compound treatment 0.375 0.0347 2.88 0.366 0.0253 2.24 3.6186 0.9922 1879740 CBMicro_032483 COc1cc2c(cc1NS(=O)(=O)c3ccc(cc3)[N+](=O)[O-])oc4ccccc42 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I06 compound treatment 0.353 0.0127 1.05 0.354 0.0133 1.17 1.5751 0.9985 1941858 CBMicro_032484 COc1ccc(cc1)C2=N/C(=C/c3cccc4ccccc34)/C(=O)O2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I07 compound treatment 0.342 0.00169 0.14 0.331 -0.00975 -0.86 -0.5119 -0.5848 1941859 CBMicro_032485 CN1CCN(CC1)C2=NC(=O)/C(=C/c3ccc(Cl)cc3Cl)/S2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I08 compound treatment 0.345 0.00469 0.39 0.351 0.0103 0.91 0.9175 0.9284 1141581 CBMicro_032486 C=CCc1cccc2cc(C(=O)NC3CCCCC3)c(=O)oc12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I09 compound treatment 0.347 0.00669 0.56 0.349 0.00825 0.73 0.9096 0.9908 1179915 CBMicro_032487 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccccc4o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I10 compound treatment 0.344 0.00369 0.31 0.344 0.00325 0.29 0.4201 0.9995 1182176 CBMicro_032488 COC(=O)c1nc[nH]c1C(=O)Nc2ccc(C)cc2C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I11 compound treatment 0.348 0.00769 0.64 0.35 0.00925 0.82 1.0309 0.9923 1941860 CBMicro_032489 O=c1[nH]c(N/N=C/c2cccs2)nnc1c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I12 compound treatment 0.337 -0.00331 -0.28 0.339 -0.00175 -0.16 -0.3041 -0.9633 1941861 CBMicro_032490 Oc1cccc(C=C2C(=O)NC(=O)NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I13 compound treatment 0.363 0.0227 1.88 0.37 0.0293 2.59 3.1648 0.9877 1941862 CBMicro_032491 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I14 compound treatment 0.341 6.88E-4 0.06 0.342 0.00125 0.11 0.1187 0.9524 1941863 CBMicro_032492 CC(CO)(CO)NC(=O)C(F)(F)C(F)(F)C(=O)NC(C)(CO)CO 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I15 compound treatment 0.342 0.00169 0.14 0.327 -0.0138 -1.22 -0.7626 -0.6217 1779269 CBMicro_032493 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(Cl)cn3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I16 compound treatment 0.346 0.00569 0.47 0.337 -0.00375 -0.33 0.0989 0.1713 1205628 CBMicro_032494 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(I)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I17 compound treatment 0.387 0.0467 3.88 0.408 0.0673 5.96 6.9549 0.9783 1941864 CBMicro_032495 Clc1cccc(c1)C(=O)Nc2cccc(NC(=O)c3ccc4ccccc4c3)c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I18 compound treatment 0.341 6.88E-4 0.06 0.35 0.00925 0.82 0.62 0.7545 1284356 CBMicro_032496 OC(=O)c1ccccc1NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I19 compound treatment 0.348 0.00769 0.64 0.337 -0.00375 -0.33 0.2163 0.3006 1941865 CBMicro_032497 Cc1c(N2C(=O)S/C(=C\c3ccccc3)/C2=O)c(=O)n(c4ccccc4)n1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I20 compound treatment 0.359 0.0187 1.55 0.358 0.0173 1.53 2.178 1.0 1780552 CBMicro_032498 OCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I21 compound treatment 0.375 0.0347 2.88 0.381 0.0403 3.57 4.5585 0.9944 1941866 CBMicro_032499 CCOC(=O)c1sc(NN=C2C(=O)CCCC2=O)c(C(=O)OCC)c1C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I22 compound treatment 0.393 0.0527 4.37 0.383 0.0423 3.74 5.7405 0.997 1941867 CBMicro_032500 OC(=O)CN1C(=O)/C(=C\c2cccc(OC(=O)c3ccco3)c2)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I23 positive control 0.153 -0.187 -15.55 0.091 -0.25 -22.13 -26.6465 -0.9851 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 I24 positive control 0.091 -0.249 -20.7 0.096 -0.245 -21.69 -29.9727 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J01 mock treatment 0.329 -0.0113 -0.94 0.343 0.00225 0.2 -0.5231 -0.5448 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J02 mock treatment 0.351 0.0107 0.89 0.352 0.0113 1.0 1.3324 0.9983 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J03 compound treatment 0.338 -0.00231 -0.19 0.329 -0.0118 -1.04 -0.8721 -0.8236 1649376 CBMicro_032501 O=C(Cc1ccccc1)Nc2ccc3OCCOc3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J04 compound treatment 0.36 0.0197 1.63 0.354 0.0133 1.17 1.986 0.9868 1715850 CBMicro_032502 CC(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccnc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J05 compound treatment 0.344 0.00369 0.31 0.35 0.00925 0.82 0.7961 0.9098 1941868 CBMicro_032503 CCOC(=O)c1ccc(cc1)c2ccc(/C=N/O)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J06 compound treatment 0.34 -3.12E-4 -0.03 0.337 -0.00375 -0.33 -0.2533 -0.76 1941869 CBMicro_032504 Clc1ccccc1Cn2cc(C=O)c3ccccc23 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J07 compound treatment 0.385 0.0447 3.71 0.369 0.0283 2.5 4.3936 0.9817 1941870 CBMicro_032505 Oc1ccc(cc1/C=N/Nc2nc(cs2)c3ccc(Br)cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J08 compound treatment 0.344 0.00369 0.31 0.346 0.00525 0.47 0.5455 0.9794 1304729 CBMicro_032506 COC(=O)c1cc(Cl)c(NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J09 compound treatment 0.344 0.00369 0.31 0.349 0.00825 0.73 0.7335 0.9253 1941871 CBMicro_032507 COc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccco4)c5ccccc5 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J10 compound treatment 0.355 0.0147 1.22 0.357 0.0163 1.44 1.8805 0.9966 1941872 CBMicro_032508 CCOc1ccc(N/C(=C/c2scc(c3ccccc3)[n+]2c4ccccc4)/C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J11 compound treatment 0.384 0.0437 3.63 0.386 0.0452 4.01 5.4002 0.9987 1941873 CBMicro_032509 Cc1ccc(cc1)C(=O)N/C(=C/c2ccc(Br)cc2)/c3nc4ccccc4[nH]3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J12 compound treatment 0.341 6.88E-4 0.06 0.336 -0.00475 -0.42 -0.2573 -0.6057 1483747 CBMicro_032510 Brc1ccccc1C(=O)Nc2ccccc2C(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J13 compound treatment 0.358 0.0177 1.47 0.355 0.0143 1.26 1.9313 0.9972 1941874 CBMicro_032511 CN(C)CCN1C(C(=C(O)C1=O)C(=O)C)c2ccccc2[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J14 compound treatment 0.586 0.246 20.4 0.586 0.245 21.73 29.7913 0.9995 1941875 CBMicro_032512 CCN1C(=C(C(=O)OC)/C(=C/c2ccccc2O)/C1=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J15 compound treatment 0.349 0.00869 0.72 0.349 0.00825 0.73 1.027 1.0 1643319 CBMicro_032513 Cc1ccc(cc1)C(O)(C(=O)Nc2ccccn2)c3ccc(C)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J16 compound treatment 0.361 0.0207 1.72 0.343 0.00225 0.2 1.3554 0.7839 1941876 CBMicro_032514 CC1(O)CC(=O)C(C(C1C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J17 compound treatment 0.342 0.00169 0.14 0.355 0.0143 1.26 0.992 0.7808 1941877 CBMicro_032515 C=CCn1c(/C=C/c2ccccc2)nc3ccccc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J18 compound treatment 0.391 0.0507 4.21 0.389 0.0483 4.28 5.9991 1.0 1941878 CBMicro_032516 [O-][N+](=O)c1ccc(/C=C/C(=O)c2ccc(cc2)c3ccccc3)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J19 compound treatment 0.344 0.00369 0.31 0.321 -0.0198 -1.75 -1.0212 -0.5747 1783820 CBMicro_032517 CCN(CC)CCSc1nc(O)c(CCC(C)C)c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J20 compound treatment 0.36 0.0197 1.63 0.36 0.0193 1.71 2.362 0.9998 1595958 CBMicro_032518 Cc1ccc(NC(=O)COc2cc(C)cc(C)c2)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J21 compound treatment 0.351 0.0107 0.89 0.337 -0.00375 -0.33 0.3924 0.4142 1236334 CBMicro_032519 CSc1ccc(CN2CCN(CC2)C(=O)c3ccccc3F)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J22 compound treatment 0.357 0.0167 1.39 0.353 0.0123 1.09 1.7473 0.9927 1365571 CBMicro_032520 Clc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)c(c1)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J23 positive control 0.152 -0.188 -15.63 0.091 -0.25 -22.13 -26.7052 -0.9855 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 J24 positive control 0.093 -0.247 -20.53 0.097 -0.244 -21.6 -29.7927 -0.9997 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K01 mock treatment 0.336 -0.00431 -0.36 0.345 0.00425 0.38 0.0132 0.0253 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K02 mock treatment 0.343 0.00269 0.22 0.341 2.5E-4 0.02 0.1734 0.7735 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K03 compound treatment 0.338 -0.00231 -0.19 0.335 -0.00575 -0.51 -0.4961 -0.911 1357098 CBMicro_032521 CC(Oc1ccccc1)C(=O)Nc2ccccc2C(=O)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K04 compound treatment 0.356 0.0157 1.3 0.384 0.0432 3.83 3.6312 0.897 1941879 CBMicro_032522 Oc1ccc(cc1)N2C(=O)/C(=C/c3c[nH]c4ccccc34)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K05 compound treatment 0.358 0.0177 1.47 0.365 0.0243 2.15 2.5579 0.9828 1941880 CBMicro_032523 COC(=O)c1ccc(cc1)N2C(=O)CC(S/C(=N/c3ccccc3)/NCCc4ccccc4)C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K06 compound treatment 0.343 0.00269 0.22 0.351 0.0103 0.91 0.8001 0.8554 1941881 CBMicro_032524 CCOC(=O)c1c(C)c(sc1NC(=O)CCN2C(=O)c3ccccc3C2=O)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K07 compound treatment 0.347 0.00669 0.56 0.334 -0.00675 -0.6 -0.0304 -0.0373 1541900 CBMicro_032525 Oc1cccc(NC(=O)c2cccc(NC(=O)c3ccc(Cl)c(Cl)c3)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K08 compound treatment 0.554 0.214 17.74 0.545 0.204 18.1 25.3435 0.9999 1941882 CBMicro_032526 O=C(NC(=S)Nc1nc[nH]n1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K09 compound treatment 0.344 0.00369 0.31 0.353 0.0123 1.09 0.9841 0.8725 1941883 CBMicro_032527 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3ccco3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K10 compound treatment 0.328 -0.0123 -1.02 0.335 -0.00575 -0.51 -1.0831 -0.9483 1437262 CBMicro_032528 CSc1nc2sc3CN(C)CCc3c2c(=O)n1Cc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K11 compound treatment 0.355 0.0147 1.22 0.36 0.0193 1.71 2.0685 0.9864 1527316 CBMicro_032529 CCOC(=O)c1cc(nc2ccccc12)c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K12 compound treatment 0.348 0.00769 0.64 0.343 0.00225 0.2 0.5923 0.8858 1941884 CBMicro_032530 O=C/1NC(=S)S\C1=C\c2ccncc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K13 compound treatment 0.437 0.0967 8.03 0.434 0.0933 8.26 11.5194 0.9999 1941885 CBMicro_032531 FC(F)(F)c1cccc(c1)c2ccc(/C=C(\C#N)/c3ccc(Cl)cc3)o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K14 compound treatment 0.475 0.135 11.18 0.423 0.0823 7.29 13.0608 0.9785 1159696 CBMicro_032532 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4cccc(CC=C)c4oc3=O)cc2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K15 compound treatment 0.432 0.0917 7.61 0.446 0.105 9.33 11.9779 0.9949 1941886 CBMicro_032533 COc1cc(/C=N/N2C(=O)CSC2=S)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K16 compound treatment 0.355 0.0147 1.22 0.356 0.0153 1.35 1.8178 0.9987 1941887 CBMicro_032534 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3ccc(C=O)cc3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K17 compound treatment 0.339 -0.00131 -0.11 0.338 -0.00275 -0.24 -0.2494 -0.9341 1941888 CBMicro_032535 CN1CCN(CC1)/N=C/C=C/c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K18 compound treatment 0.34 -3.12E-4 -0.03 0.342 0.00125 0.11 0.06 0.5272 1118087 CBMicro_032536 CCOc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(OC)c(OC)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K19 compound treatment 0.336 -0.00431 -0.36 0.34 -7.5E-4 -0.07 -0.3002 -0.8243 1941889 CBMicro_032537 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3ccc(OC)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K20 compound treatment 0.389 0.0487 4.04 0.384 0.0432 3.83 5.5684 0.9996 1941890 CBMicro_032538 COc1ccc(Nc2cc(C)nc3c(C)ccc([N+](=O)[O-])c23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K21 compound treatment 0.392 0.0517 4.29 0.396 0.0553 4.9 6.4965 0.9978 1941891 CBMicro_032539 [O-][N+](=O)c1ccc(cc1NCc2ccccc2)N3CCN(CC3)c4ccc(cc4[N+](=O)[O-])C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K22 compound treatment 0.345 0.00469 0.39 0.337 -0.00375 -0.33 0.0402 0.0785 1432380 CBMicro_032540 CCOC(=O)c1c(NC(=O)COc2ccc(Br)c(C)c2)sc3CCCc13 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K23 positive control 0.177 -0.163 -13.56 0.09 -0.251 -22.22 -25.3003 -0.9719 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 K24 positive control 0.15 -0.19 -15.8 0.097 -0.244 -21.6 -26.4466 -0.9882 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L01 mock treatment 0.339 -0.00131 -0.11 0.341 2.5E-4 0.02 -0.0614 -0.552 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L02 mock treatment 0.343 0.00269 0.22 0.34 -7.5E-4 -0.07 0.1108 0.4758 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L03 compound treatment 0.372 0.0317 2.63 0.366 0.0253 2.24 3.4425 0.9968 1941892 CBMicro_032541 CCN1C(=O)/C(=C\c2cn(Cc3ccccc3Cl)c4ccccc24)/SC1=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L04 compound treatment 0.353 0.0127 1.05 0.346 0.00525 0.47 1.0738 0.9325 1564403 CBMicro_032542 CCN(CC)c1ccc(cc1)C2C(C(=O)OC(C)C)C(=O)CC(C)(O)C2C(=O)OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L05 compound treatment 0.369 0.0287 2.38 0.365 0.0243 2.15 3.2037 0.9987 1941893 CBMicro_032543 Cc1cc(Nc2ccccc2)c3c(cc(C)c(C)c3n1)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L06 compound treatment 0.354 0.0137 1.14 0.348 0.00725 0.64 1.2578 0.9636 1941894 CBMicro_032544 OC1=C(C(N(C1=O)c2ccccc2)c3ccccc3)C(=O)c4ccc(Br)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L07 compound treatment 0.401 0.0607 5.04 0.436 0.0953 8.44 9.5314 0.9696 1941895 CBMicro_032545 COc1cc(/C=N/Nc2nc(c(s2)c3ccccc3)c4ccccc4)ccc1O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L08 compound treatment 0.323 -0.0173 -1.44 0.332 -0.00875 -0.78 -1.5646 -0.9581 1722708 CBMicro_032546 C=CCn1c(COc2ccc3ccccc3c2)nc4ccccc14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L09 compound treatment 0.377 0.0367 3.05 0.387 0.0462 4.1 5.0519 0.9893 1374268 CBMicro_032547 COc1cccc(c1)c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L10 compound treatment 0.394 0.0537 4.46 0.43 0.0892 7.91 8.7445 0.9632 1941896 CBMicro_032548 COc1ccc(N/C(=C/C2=[N+](c3ccccc3)C(O)(CS2)c4ccccc4)/C)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L11 compound treatment 0.342 0.00169 0.14 0.346 0.00525 0.47 0.4281 0.881 1941897 CBMicro_032549 CCOC(=O)c1c(C)c(sc1NC(=O)COc2cc(Cl)ccc2Cl)C(=O)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L12 compound treatment 0.346 0.00569 0.47 0.334 -0.00675 -0.6 -0.0891 -0.1169 1941898 CBMicro_032550 FC(F)(F)c1ccccc1CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L13 compound treatment 0.352 0.0117 0.97 0.35 0.00925 0.82 1.2657 0.9965 1228733 CBMicro_032551 CC(C)OC(=O)C1C(C(C(=O)OC(C)C)C(C)(O)CC1=O)c2ccc(C)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L14 compound treatment 0.34 -3.12E-4 -0.03 0.332 -0.00875 -0.78 -0.5667 -0.7304 1941899 CBMicro_032552 CC(=O)C1=C(O)C(=O)N(CCN2CCNCC2)C1c3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L15 compound treatment 0.369 0.0287 2.38 0.365 0.0243 2.15 3.2037 0.9987 1941900 CBMicro_032553 [O-][N+](=O)c1ccc2N/C(=C/C(=O)c3ccc(Br)cc3)/C(=O)Oc2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L16 compound treatment 0.331 -0.00931 -0.77 0.334 -0.00675 -0.6 -0.9697 -0.992 1566383 CBMicro_032554 COc1ccc(Br)cc1CN2CCN(CC2)C3CCCCC3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L17 compound treatment 0.377 0.0367 3.05 0.374 0.0333 2.95 4.2373 0.9999 1706872 CBMicro_032555 OC1=C(C(N(C1=O)c2cccnc2)c3ccc(Cl)cc3)C(=O)c4ccc(Cl)cc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L18 compound treatment 0.331 -0.00931 -0.77 0.335 -0.00575 -0.51 -0.907 -0.9795 1632378 CBMicro_032556 CCC(CC)N1CCN(Cc2cccc(Cl)c2)CC1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L19 compound treatment 0.333 -0.00731 -0.61 0.334 -0.00675 -0.6 -0.8523 -1.0 1119225 CBMicro_032557 CCc1ccc(CN2CCN(Cc3ccc(OC)cc3OC)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L20 compound treatment 0.339 -0.00131 -0.11 0.342 0.00125 0.11 0.0013 0.0083 1941901 CBMicro_032558 CCOC(=O)COc1cc(C)ccc1C(C)(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L21 compound treatment 0.346 0.00569 0.47 0.341 2.5E-4 0.02 0.3495 0.7395 1450160 CBMicro_032559 O=C(N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L22 compound treatment 0.34 -3.12E-4 -0.03 0.338 -0.00275 -0.24 -0.1907 -0.778 1160943 CBMicro_032560 COc1ccc(NC(=O)c2c(Cl)ccc(Cl)c2OC)c(OC)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L23 positive control 0.187 -0.153 -12.73 0.092 -0.249 -22.04 -24.5879 -0.9659 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 L24 positive control 0.148 -0.192 -15.97 0.097 -0.244 -21.6 -26.564 -0.9889 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M01 mock treatment 0.337 -0.00331 -0.28 0.341 2.5E-4 0.02 -0.1788 -0.648 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M02 mock treatment 0.337 -0.00331 -0.28 0.337 -0.00375 -0.33 -0.4294 -0.9956 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M03 compound treatment 0.338 -0.00231 -0.19 0.333 -0.00775 -0.69 -0.6214 -0.8714 1941902 CBMicro_032561 Cc1cc(OCc2ccc(cc2)[N+](=O)[O-])c3c(cc(=O)oc3c1)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M04 compound treatment 0.341 6.88E-4 0.06 0.336 -0.00475 -0.42 -0.2573 -0.6057 1330520 CBMicro_032562 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M05 compound treatment 0.335 -0.00531 -0.44 0.339 -0.00175 -0.16 -0.4215 -0.9016 1941903 CBMicro_032563 OC(=O)CCC(=O)N(CCc1ccccc1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M06 compound treatment 0.595 0.255 21.14 0.482 0.141 12.52 23.8024 0.9687 1941904 CBMicro_032564 Cc1nn(c(O)c1/C=C\2/C(=O)NN(C2=O)c3ccc(I)cc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M07 compound treatment 0.425 0.0847 7.03 0.418 0.0772 6.85 9.8123 0.9999 1941905 CBMicro_032565 CC/1=NN(C(=O)\C1=C\NN2CCOCC2)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M08 compound treatment 0.354 0.0137 1.14 0.343 0.00225 0.2 0.9445 0.8187 1941906 CBMicro_032566 O=c1[nH]nc(SCc2cccc3ccccc23)c(=O)[nH]1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M09 compound treatment 0.403 0.0627 5.2 0.405 0.0643 5.69 7.7062 0.999 1941907 CBMicro_032567 COc1cc(ccc1[N+](=O)[O-])N2CCCCC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M10 compound treatment 0.416 0.0757 6.28 0.45 0.109 9.68 11.2893 0.9781 1941908 CBMicro_032568 N=c1sc(=S)[nH]c2sc3CN(Cc4ccccc4)CCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M11 compound treatment 0.342 0.00169 0.14 0.346 0.00525 0.47 0.4281 0.881 1941909 CBMicro_032569 Nc1cccc(c1)c2nc3cccc4cccc([nH]2)c43 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M12 compound treatment 0.355 0.0147 1.22 0.35 0.00925 0.82 1.4419 0.9813 1941910 CBMicro_032570 Cc1ccc(C=C2C(=O)NC(=O)NC2=O)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M13 compound treatment 0.231 -0.109 -9.08 0.232 -0.109 -9.64 -13.2318 -0.9995 1264058 CBMicro_032571 CCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M14 compound treatment 0.345 0.00469 0.39 0.357 0.0163 1.44 1.2935 0.8671 1941911 CBMicro_032572 Clc1cccc(/C=C\2/SC(=O)NC2=O)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M15 compound treatment 0.342 0.00169 0.14 0.339 -0.00175 -0.16 -0.0106 -0.0507 1294896 CBMicro_032573 Fc1ccc(NC(=O)CCN2C(=O)c3ccccc3C2=O)cc1Cl 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M16 compound treatment 0.33 -0.0103 -0.86 0.335 -0.00575 -0.51 -0.9657 -0.9693 1453797 CBMicro_032574 CCOC(=O)c1ccc(cc1)N2C(=O)C3CC=C(C)CC3C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M17 compound treatment 0.381 0.0407 3.38 0.376 0.0352 3.12 4.5974 0.9992 1394508 CBMicro_032575 O=c1[nH]c(SCC#C)nc2sc3CCCCc3c12 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M18 compound treatment 0.338 -0.00231 -0.19 0.333 -0.00775 -0.69 -0.6214 -0.8714 1864190 CBMicro_032576 [O-][N+](=O)c1ccccc1C(=O)CSc2n[nH]c(=O)[nH]c2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M19 compound treatment 0.371 0.0307 2.55 0.369 0.0283 2.5 3.5717 1.0 1941912 CBMicro_032577 CC/1=NN(C(=O)\C1=C\NCCN2CCN(CC2)C(=O)c3cccc(F)c3)c4ccc(cc4)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M20 compound treatment 0.34 -3.12E-4 -0.03 0.348 0.00725 0.64 0.436 0.678 1248356 CBMicro_032578 COc1ccc(Nc2cc(C)nc3c(C)cccc23)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M21 compound treatment 0.724 0.384 31.85 0.715 0.374 33.17 45.9761 0.9998 1941913 CBMicro_032579 CN1CCN(CC1)/N=C/c2ccc(s2)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M22 compound treatment 0.331 -0.00931 -0.77 0.333 -0.00775 -0.69 -1.0323 -0.9983 1941914 CBMicro_032580 CSc1ccc(CN2CCN(Cc3ccccc3C(F)(F)F)CC2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M23 positive control 0.193 -0.147 -12.23 0.09 -0.251 -22.22 -24.361 -0.9604 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 M24 positive control 0.161 -0.179 -14.89 0.097 -0.244 -21.6 -25.8009 -0.9835 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N01 mock treatment 0.344 0.00369 0.31 0.341 2.5E-4 0.02 0.2321 0.7563 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N02 mock treatment 0.344 0.00369 0.31 0.346 0.00525 0.47 0.5455 0.9794 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N03 compound treatment 0.362 0.0217 1.8 0.362 0.0213 1.88 2.6048 0.9997 1941915 CBMicro_032581 CCCC(=O)Nc1nc(cs1)c2ccccc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N04 compound treatment 0.386 0.0457 3.79 0.377 0.0362 3.21 4.9536 0.9966 1941916 CBMicro_032582 CCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc1OC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N05 compound treatment 0.354 0.0137 1.14 0.352 0.0113 1.0 1.5085 0.9979 1232217 CBMicro_032583 Clc1ccc(C(=O)Nc2cccc(NC(=O)COc3ccccc3)c2)c(Cl)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N06 compound treatment 0.339 -0.00131 -0.11 0.34 -7.5E-4 -0.07 -0.124 -0.9719 1438373 CBMicro_032584 C(CN1CCN(CC1)C2CCCC2)Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N07 compound treatment 0.351 0.0107 0.89 0.334 -0.00675 -0.6 0.2044 0.191 1524405 CBMicro_032585 NC(=O)Cc1ccc2sc(nc2c1)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N08 compound treatment 0.349 0.00869 0.72 0.335 -0.00575 -0.51 0.1497 0.1695 1941917 CBMicro_032586 CCCc1nc2ccccc2n1Cc3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N09 compound treatment 0.356 0.0157 1.3 0.344 0.00325 0.29 1.1246 0.8431 1941918 CBMicro_032587 Cc1ccc(cc1)N2C(=O)/C(=C/c3cc(Br)ccc3O)/C(=O)NC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N10 compound treatment 0.344 0.00369 0.31 0.339 -0.00175 -0.16 0.1068 0.3112 1783340 CBMicro_032588 COc1cc(OC)c(OC)cc1CN2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N11 compound treatment 0.338 -0.00231 -0.19 0.335 -0.00575 -0.51 -0.4961 -0.911 1941919 CBMicro_032589 Cc1ccc(cc1)S(=O)(=O)NCCSCc2ccc(Br)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N12 compound treatment 0.368 0.0277 2.3 0.371 0.0302 2.68 3.521 0.9971 1941920 CBMicro_032590 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccccc3[N+](=O)[O-])C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N13 compound treatment 0.357 0.0167 1.39 0.373 0.0323 2.86 3.0006 0.9447 1941921 CBMicro_032591 COc1ccc(cc1)C(=O)/C=C\2/Nc3ccccc3N(C2=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N14 compound treatment 0.35 0.00969 0.8 0.34 -7.5E-4 -0.07 0.5217 0.6465 1787306 CBMicro_032592 COc1ccc(CN2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-])cc1OCc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N15 compound treatment 0.355 0.0147 1.22 0.345 0.00425 0.38 1.1285 0.8843 1941922 CBMicro_032593 CC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(Br)cc2)C(=O)C)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N16 compound treatment 0.35 0.00969 0.8 0.347 0.00625 0.55 0.9603 0.9834 1151896 CBMicro_032594 OC1=C(C(N(Cc2cccnc2)C1=O)c3ccc(Cl)cc3Cl)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N17 compound treatment 0.335 -0.00531 -0.44 0.336 -0.00475 -0.42 -0.6095 -0.9997 1722318 CBMicro_032595 Brc1ccc(CN2CCN(CC2)C3CCCC3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N18 compound treatment 0.341 6.88E-4 0.06 0.337 -0.00375 -0.33 -0.1946 -0.5772 1330439 CBMicro_032596 CC(C)(C)c1nnc(NC(=O)CSc2nnc[nH]2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N19 compound treatment 0.379 0.0387 3.21 0.371 0.0302 2.68 4.1667 0.996 1941923 CBMicro_032597 Clc1cccc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N20 compound treatment 0.353 0.0127 1.05 0.355 0.0143 1.26 1.6378 0.9959 1366371 CBMicro_032598 Cc1ccc(NC(=O)CCOc2ccccc2)c(Br)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N21 compound treatment 0.348 0.00769 0.64 0.349 0.00825 0.73 0.9683 0.9977 1723937 CBMicro_032599 CCOc1ccc(CN2CCN(CC2)C(=O)c3cccc(F)c3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N22 compound treatment 0.343 0.00269 0.22 0.342 0.00125 0.11 0.2361 0.9478 1604794 CBMicro_032600 COc1cccc(NC(=O)COc2cc(C)ccc2C(C)C)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N23 positive control 0.205 -0.135 -11.23 0.091 -0.25 -22.13 -23.5939 -0.9506 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 N24 positive control 0.206 -0.134 -11.15 0.096 -0.245 -21.69 -23.2219 -0.9522 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O01 mock treatment 0.342 0.00169 0.14 0.344 0.00325 0.29 0.3027 0.9452 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O02 mock treatment 0.343 0.00269 0.22 0.343 0.00225 0.2 0.2988 0.9984 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O03 compound treatment 0.344 0.00369 0.31 0.343 0.00225 0.2 0.3575 0.9784 1864180 CBMicro_032601 CC(C)c1ccc(C)cc1OCC(=O)Nc2ncc(s2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O04 compound treatment 0.344 0.00369 0.31 0.344 0.00325 0.29 0.4201 0.9995 1941924 CBMicro_032602 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O05 compound treatment 0.361 0.0207 1.72 0.364 0.0233 2.06 2.6714 0.9959 1560926 CBMicro_032603 Cc1cc(NC(=O)c2ccc(Br)cc2)ccc1NC(=O)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O06 compound treatment 0.345 0.00469 0.39 0.348 0.00725 0.64 0.7295 0.9711 1491226 CBMicro_032604 COc1ccc(OCC(=O)Nc2ccc3ccccc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O07 compound treatment 0.381 0.0407 3.38 0.355 0.0143 1.26 3.2815 0.91 1941925 CBMicro_032605 CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O08 compound treatment 0.341 6.88E-4 0.06 0.344 0.00325 0.29 0.244 0.8311 1224775 CBMicro_032606 Cc1ccc(COc2ccc3c4CCCCc4c(=O)oc3c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O09 compound treatment 0.373 0.0327 2.71 0.364 0.0233 2.06 3.3758 0.9908 1701425 CBMicro_032607 Cc1ccc(cc1C)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc5OCOc5c4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O10 compound treatment 0.368 0.0277 2.3 0.365 0.0243 2.15 3.145 0.9994 1727015 CBMicro_032608 CCSc1nc2sc3CN(C)CCc3c2c4nnnn14 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O11 compound treatment 0.35 0.00969 0.8 0.345 0.00425 0.38 0.835 0.9403 1286689 CBMicro_032609 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(C)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O12 compound treatment 0.396 0.0557 4.62 0.386 0.0452 4.01 6.1046 0.9975 1941926 CBMicro_032610 CCOC(=O)NC(Nc1ccccc1[N+](=O)[O-])(C(F)(F)F)C(F)(F)F 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O13 compound treatment 0.355 0.0147 1.22 0.35 0.00925 0.82 1.4419 0.9813 1660106 CBMicro_032611 O=C(Nc1nccs1)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O14 compound treatment 0.35 0.00969 0.8 0.345 0.00425 0.38 0.835 0.9403 1941927 CBMicro_032612 COc1cccc(c1)c2nnc(o2)c3ccc(Br)o3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O15 compound treatment 0.343 0.00269 0.22 0.352 0.0113 1.0 0.8627 0.8445 1160505 CBMicro_032613 CCN1C(=C(C(NC1=O)c2cc(Br)c(O)c(OC)c2)C(=O)OCC=C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O16 compound treatment 0.391 0.0507 4.21 0.383 0.0423 3.74 5.6231 0.9983 1941928 CBMicro_032614 CCOC(=O)c1ccc(cc1)N2NC(=O)/C(=C/c3ccc(OCC=C)c(OC)c3)/C2=O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O17 compound treatment 0.309 -0.0313 -2.6 0.311 -0.0297 -2.64 -3.7024 -1.0 1941929 CBMicro_032615 CC1(C)OC(=O)C(=Cc2ccc(I)o2)C(=O)O1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O18 compound treatment 0.342 0.00169 0.14 0.347 0.00625 0.55 0.4907 0.8589 1941930 CBMicro_032616 COc1cc(ccc1NC(=O)COc2ccccc2C(C)(C)C)[N+](=O)[O-] 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O19 compound treatment 0.361 0.0207 1.72 0.357 0.0163 1.44 2.2327 0.9962 1941931 CBMicro_032617 CCCCOc1ccc(cc1)C(=O)Nc2cccc(c3nc4cc(C)ccc4o3)c2C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O20 compound treatment 0.339 -0.00131 -0.11 0.345 0.00425 0.38 0.1893 0.4827 1941932 CBMicro_032618 CCCCn1c(nc2ccccc12)c3ccccc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O21 compound treatment 0.353 0.0127 1.05 0.355 0.0143 1.26 1.6378 0.9959 1459743 CBMicro_032619 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O22 compound treatment 0.452 0.112 9.27 0.435 0.0943 8.35 12.4626 0.9986 1941933 CBMicro_032620 Clc1ccccc1/C=C/C(=O)c2ccc(NC(=O)c3cccs3)cc2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O23 positive control 0.233 -0.107 -8.91 0.092 -0.249 -22.04 -21.8875 -0.9205 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 O24 positive control 0.172 -0.168 -13.97 0.1 -0.241 -21.34 -24.9671 -0.9789 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P01 mock treatment 0.34 -3.12E-4 -0.03 0.339 -0.00175 -0.16 -0.128 -0.8141 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P02 mock treatment 0.345 0.00469 0.39 0.34 -7.5E-4 -0.07 0.2282 0.578 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P03 compound treatment 0.354 0.0137 1.14 0.35 0.00925 0.82 1.3832 0.9872 1941934 CBMicro_032621 CCCCOC(=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P04 compound treatment 0.296 -0.0443 -3.68 0.322 -0.0187 -1.66 -3.7763 -0.9355 1941935 CBMicro_032622 O=C(/C=C\1/Nc2ccccc2N(C1=O)c3ccccc3)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P05 compound treatment 0.34 -3.12E-4 -0.03 0.348 0.00725 0.64 0.436 0.678 1941936 CBMicro_032623 CCOC(=O)COc1ccccc1/C=C/2\C(=NN(C2=O)c3ccccc3)O 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P06 compound treatment 0.377 0.0367 3.05 0.384 0.0432 3.83 4.8639 0.9935 1434854 CBMicro_032624 CC(C)COC(=O)c1ccc(NC(=O)COc2ccccc2Cl)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P07 compound treatment 0.365 0.0247 2.05 0.357 0.0163 1.44 2.4675 0.9851 1600413 CBMicro_032625 NC(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P08 compound treatment 0.355 0.0147 1.22 0.349 0.00825 0.73 1.3792 0.9701 1941937 CBMicro_032626 COc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3I)cc1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P09 compound treatment 0.348 0.00769 0.64 0.342 0.00125 0.11 0.5296 0.8176 1941938 CBMicro_032627 [O-][N+](=O)c1cccc(/C=C(/NC(=O)c2ccccc2)\C(=O)N3CCCC3)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P10 compound treatment 0.383 0.0427 3.54 0.382 0.0413 3.66 5.0908 0.9999 1941939 CBMicro_032628 CCOc1cc(/C=N/n2cnnc2)ccc1OCCOc3ccc(cc3)C(C)CC 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P11 compound treatment 0.367 0.0267 2.22 0.367 0.0262 2.33 3.2116 0.9997 1275507 CBMicro_032629 Cc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3)c(c1)C(=O)c4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P12 compound treatment 0.337 -0.00331 -0.28 0.336 -0.00475 -0.42 -0.4921 -0.9787 1787304 CBMicro_032630 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(CC3CCC=CC3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P13 compound treatment 0.335 -0.00531 -0.44 0.338 -0.00275 -0.24 -0.4842 -0.9609 1287192 CBMicro_032631 Clc1ccc(cc1)S(=O)(=O)N2CCN(CCCc3ccccc3)CC2 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P14 compound treatment 0.351 0.0107 0.89 0.352 0.0113 1.0 1.3324 0.9983 1941940 CBMicro_032632 COc1ccc(cc1)C2C(C(=O)C)C(C)(O)CC(=C2C(=O)C)Nc3ccc(Br)cc3 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P15 compound treatment 0.342 0.00169 0.14 0.341 2.5E-4 0.02 0.1147 0.8089 1941941 CBMicro_032633 C/C(=N\O)/c1ccc2c3CCCCc3[nH]c2c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P16 compound treatment 0.341 6.88E-4 0.06 0.342 0.00125 0.11 0.1187 0.9524 1417078 CBMicro_032634 C(c1ccco1)n2c(nc3ccccc23)c4ccco4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P17 compound treatment 0.345 0.00469 0.39 0.351 0.0103 0.91 0.9175 0.9284 1415871 CBMicro_032635 C(Oc1ccccc1)c2nc3ccccc3n2Cc4ccccc4 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P18 compound treatment 0.339 -0.00131 -0.11 0.333 -0.00775 -0.69 -0.5627 -0.8092 1447658 CBMicro_032636 CCCc1nnc(NC(=O)CSc2nnc[nH]2)s1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P19 compound treatment 0.349 0.00869 0.72 0.342 0.00125 0.11 0.5883 0.8063 1941942 CBMicro_032637 Cc1ccc(/C=C(/NC(=O)c2ccccc2I)\C(=O)O)o1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P20 compound treatment 0.357 0.0167 1.39 0.352 0.0113 1.0 1.6846 0.987 1396032 CBMicro_032638 COc1ccc(OC)c(NC(=O)COc2ccc(Cl)c(C)c2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P21 compound treatment 0.352 0.0117 0.97 0.347 0.00625 0.55 1.0778 0.9646 1272811 CBMicro_032639 CCOc1ccc(cc1)C2C(C(=O)OC(C)C)C(=O)CC(C)(O)C2C(=O)OC(C)C 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P22 compound treatment 0.331 -0.00931 -0.77 0.343 0.00225 0.2 -0.4057 -0.5081 1450004 CBMicro_032640 Clc1cccc(OCC(=O)Nc2ccc(OCc3ccccc3)cc2)c1 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P23 positive control 0.183 -0.157 -13.06 0.095 -0.246 -21.78 -24.6347 -0.9701 1017.0015 EnzCoupledColor(1017.0015) TrypanothioneReductase 1017.0015.787 P24 positive control 0.19 -0.15 -12.48 0.098 -0.243 -21.51 -24.0358 -0.9664