ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A01 compound treatment 0.344 -0.0259 -2.09 0.343 -0.00894 -0.81 -2.0503 -0.9152 1952578 ICCB4_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A02 compound treatment 0.349 -0.0209 -1.69 0.344 -0.00794 -0.72 -1.7014 -0.9281 1952579 ICCB4_000002 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A03 compound treatment 0.361 -0.00893 -0.72 0.378 0.0261 2.37 1.1642 0.4708 1952580 ICCB4_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A04 compound treatment 0.347 -0.0229 -1.85 0.349 -0.00294 -0.27 -1.4944 -0.8009 1952581 ICCB4_000004 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A05 compound treatment 0.35 -0.0199 -1.61 0.37 0.0181 1.64 0.0243 0.0106 1952582 ICCB4_000005 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A06 compound treatment 0.365 -0.00493 -0.4 0.369 0.0171 1.55 0.8143 0.5092 1952583 ICCB4_000006 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A07 compound treatment 0.318 -0.0519 -4.18 0.336 -0.0159 -1.45 -3.9801 -0.8994 1952584 ICCB4_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A08 compound treatment 0.362 -0.00793 -0.64 0.352 6.25E-5 0.01 -0.4477 -0.7008 1952585 ICCB4_000008 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A09 compound treatment 0.359 -0.0109 -0.88 0.36 0.00806 0.73 -0.1051 -0.0918 1952586 ICCB4_000009 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A10 compound treatment 0.385 0.0151 1.21 0.378 0.0261 2.37 2.5307 0.9519 1952587 ICCB4_000010 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A11 compound treatment 0.345 -0.0249 -2.01 0.345 -0.00694 -0.63 -1.865 -0.8863 1952588 ICCB4_000011 CCOC(=O)C(Cc1ccccc1)NC(=O)O[C@@H]2C[C@@H](CCC3CC(=NO3)CC)O[C@]4(CCC[C@H](COC(=O)NCCC(C)C)O4)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A12 compound treatment 0.397 0.0271 2.18 0.407 0.0551 5.0 5.0754 0.9308 1952589 ICCB4_000012 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A13 compound treatment 0.377 0.00707 0.57 0.389 0.0371 3.36 2.7812 0.8151 1952590 ICCB4_000013 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A14 compound treatment 0.344 -0.0259 -2.09 0.345 -0.00694 -0.63 -1.9219 -0.8811 1952591 ICCB4_000014 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A15 compound treatment 0.347 -0.0229 -1.85 0.343 -0.00894 -0.81 -1.8795 -0.9318 1952592 ICCB4_000015 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A16 compound treatment 0.348 -0.0219 -1.77 0.341 -0.0109 -0.99 -1.9509 -0.9629 1952593 ICCB4_000016 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A17 compound treatment 0.362 -0.00793 -0.64 0.355 0.00306 0.28 -0.2552 -0.3662 1952594 ICCB4_000017 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A18 compound treatment 0.377 0.00707 0.57 0.38 0.0281 2.55 2.2036 0.8443 1952595 ICCB4_000018 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A19 compound treatment 0.343 -0.0269 -2.17 0.338 -0.0139 -1.27 -2.4282 -0.9671 1952596 ICCB4_000019 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A20 compound treatment 0.357 -0.0129 -1.04 0.365 0.0131 1.19 0.102 0.0646 1952597 ICCB4_000020 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A21 compound treatment 0.368 -0.00193 -0.16 0.389 0.0371 3.36 2.2688 0.6737 1952598 ICCB4_000021 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A22 compound treatment 0.339 -0.0309 -2.49 0.33 -0.0219 -1.99 -3.1694 -0.9938 1952599 ICCB4_000022 CCC1=NOC(CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A23 mock treatment 0.334 -0.0359 -2.89 0.34 -0.0119 -1.08 -2.8123 -0.9102 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 A24 positive control 0.09 -0.28 -22.54 0.085 -0.267 -24.23 -33.073 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B01 compound treatment 0.383 0.0131 1.05 0.373 0.0211 1.91 2.0959 0.9604 1952600 ICCB4_000023 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B02 compound treatment 0.376 0.00607 0.49 0.373 0.0211 1.91 1.6973 0.8602 1952601 ICCB4_000024 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B03 compound treatment 0.385 0.0151 1.21 0.355 0.00306 0.28 1.0545 0.8472 1952602 ICCB4_000025 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B04 compound treatment 0.353 -0.0169 -1.36 0.36 0.00806 0.73 -0.4467 -0.2887 1952603 ICCB4_000026 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B05 compound treatment 0.38 0.0101 0.81 0.362 0.0101 0.91 1.2191 0.9982 1952604 ICCB4_000027 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B06 compound treatment 0.384 0.0141 1.13 0.385 0.0331 3.0 2.9231 0.9112 1952605 ICCB4_000028 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B07 compound treatment 0.384 0.0141 1.13 0.376 0.0241 2.18 2.3454 0.9533 1952606 ICCB4_000029 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B08 compound treatment 0.379 0.00907 0.73 0.372 0.0201 1.82 1.804 0.9195 1952607 ICCB4_000030 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B09 compound treatment 0.396 0.0261 2.1 0.397 0.0451 4.09 4.3766 0.9519 1952608 ICCB4_000031 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B10 compound treatment 0.417 0.0471 3.79 0.398 0.0461 4.18 5.6365 0.9988 1952609 ICCB4_000032 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B11 compound treatment 0.412 0.0421 3.39 0.403 0.0511 4.64 5.6728 0.9881 1952610 ICCB4_000033 CCC1=NOC(CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B12 compound treatment 0.405 0.0351 2.82 0.398 0.0461 4.18 4.9533 0.9817 1952611 ICCB4_000034 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccccc4)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B13 compound treatment 0.4 0.0301 2.42 0.384 0.0321 2.91 3.77 0.9958 1952612 ICCB4_000035 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B14 compound treatment 0.379 0.00907 0.73 0.366 0.0141 1.28 1.4189 0.9649 1952613 ICCB4_000036 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7OCOc76 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B15 compound treatment 0.393 0.0231 1.86 0.394 0.0421 3.82 4.0132 0.9452 1952614 ICCB4_000037 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B16 compound treatment 0.374 0.00407 0.33 0.365 0.0131 1.19 1.07 0.8698 1952615 ICCB4_000038 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5OCOc54 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B17 compound treatment 0.379 0.00907 0.73 0.361 0.00906 0.82 1.0979 0.9982 1952616 ICCB4_000039 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5OCOc54 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B18 compound treatment 0.387 0.0171 1.37 0.383 0.0311 2.82 2.9655 0.9454 1952617 ICCB4_000040 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B19 compound treatment 0.371 0.00107 0.09 0.361 0.00906 0.82 0.6424 0.7767 1952618 ICCB4_000041 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B20 compound treatment 0.398 0.0281 2.26 0.393 0.0411 3.73 4.2337 0.9713 1952619 ICCB4_000042 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B21 compound treatment 0.395 0.0251 2.02 0.383 0.0311 2.82 3.4211 0.9866 1952620 ICCB4_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6OCOc65 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B22 compound treatment 0.386 0.0161 1.29 0.364 0.0121 1.09 1.6891 0.9966 1952621 ICCB4_000044 CC(C)C[C@H](NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B23 mock treatment 0.373 0.00307 0.25 0.36 0.00806 0.73 0.6921 0.8961 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 B24 positive control 0.092 -0.278 -22.38 0.086 -0.266 -24.14 -32.895 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C01 compound treatment 0.38 0.0101 0.81 0.379 0.0271 2.46 2.3102 0.8931 1952622 ICCB4_000045 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C02 compound treatment 0.371 0.00107 0.09 0.373 0.0211 1.91 1.4126 0.7381 1952623 ICCB4_000046 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C03 compound treatment 0.374 0.00407 0.33 0.37 0.0181 1.64 1.3909 0.8319 1952624 ICCB4_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C04 compound treatment 0.377 0.00707 0.57 0.364 0.0121 1.09 1.1766 0.9535 1952625 ICCB4_000048 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C05 compound treatment 0.373 0.00307 0.25 0.369 0.0171 1.55 1.2698 0.8096 1952626 ICCB4_000049 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C06 compound treatment 0.37 6.67E-5 0.01 0.367 0.0151 1.37 0.9706 0.7099 1952627 ICCB4_000050 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C07 compound treatment 0.412 0.0421 3.39 0.405 0.0531 4.82 5.8011 0.9852 1952628 ICCB4_000051 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C08 compound treatment 0.365 -0.00493 -0.4 0.365 0.0131 1.19 0.5575 0.4458 1952629 ICCB4_000052 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C09 compound treatment 0.404 0.0341 2.74 0.4 0.0481 4.36 5.0247 0.975 1952630 ICCB4_000053 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C10 compound treatment 0.423 0.0531 4.27 0.414 0.0621 5.63 7.0051 0.9907 1952631 ICCB4_000054 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C11 compound treatment 0.38 0.0101 0.81 0.377 0.0251 2.27 2.1818 0.9034 1952632 ICCB4_000055 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C12 compound treatment 0.367 -0.00293 -0.24 0.365 0.0131 1.19 0.6714 0.5553 1952633 ICCB4_000056 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C13 compound treatment 0.366 -0.00393 -0.32 0.361 0.00906 0.82 0.3577 0.4058 1952634 ICCB4_000057 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C14 compound treatment 0.384 0.0141 1.13 0.373 0.0211 1.91 2.1529 0.9688 1952635 ICCB4_000058 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C15 compound treatment 0.37 6.67E-5 0.01 0.362 0.0101 0.91 0.6497 0.7113 1952636 ICCB4_000059 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C16 compound treatment 0.371 0.00107 0.09 0.362 0.0101 0.91 0.7066 0.7702 1952637 ICCB4_000060 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C17 compound treatment 0.37 6.67E-5 0.01 0.363 0.0111 1.0 0.7138 0.7109 1952638 ICCB4_000061 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C18 compound treatment 0.371 0.00107 0.09 0.363 0.0111 1.0 0.7708 0.7648 1952639 ICCB4_000062 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C19 compound treatment 0.368 -0.00193 -0.16 0.362 0.0101 0.91 0.5358 0.5782 1952640 ICCB4_000063 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C20 compound treatment 0.367 -0.00293 -0.24 0.365 0.0131 1.19 0.6714 0.5553 1952641 ICCB4_000064 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C21 compound treatment 0.366 -0.00393 -0.32 0.367 0.0151 1.37 0.7428 0.5293 1952642 ICCB4_000065 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C22 compound treatment 0.37 6.67E-5 0.01 0.367 0.0151 1.37 0.9706 0.7099 1952643 ICCB4_000066 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C23 mock treatment 0.368 -0.00193 -0.16 0.351 -9.38E-4 -0.09 -0.1703 -0.9596 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 C24 positive control 0.092 -0.278 -22.38 0.085 -0.267 -24.23 -32.9592 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D01 compound treatment 0.387 0.0171 1.37 0.37 0.0181 1.64 2.1311 0.9961 1952644 ICCB4_000067 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D02 compound treatment 0.377 0.00707 0.57 0.374 0.0221 2.0 1.8185 0.8735 1952645 ICCB4_000068 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D03 compound treatment 0.387 0.0171 1.37 0.385 0.0331 3.0 3.0939 0.9373 1952646 ICCB4_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D04 compound treatment 0.378 0.00807 0.65 0.357 0.00506 0.46 0.7843 0.9856 1952647 ICCB4_000070 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D05 compound treatment 0.372 0.00207 0.17 0.375 0.0231 2.09 1.5979 0.7609 1952648 ICCB4_000071 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D06 compound treatment 0.37 6.67E-5 0.01 0.369 0.0171 1.55 1.099 0.7096 1952649 ICCB4_000072 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D07 compound treatment 0.382 0.0121 0.97 0.37 0.0181 1.64 1.8464 0.9688 1952650 ICCB4_000073 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D08 compound treatment 0.377 0.00707 0.57 0.372 0.0201 1.82 1.6901 0.8858 1952651 ICCB4_000074 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D09 compound treatment 0.392 0.0221 1.78 0.388 0.0361 3.27 3.5712 0.9588 1952652 ICCB4_000075 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D10 compound treatment 0.393 0.0231 1.86 0.391 0.0391 3.55 3.8207 0.9545 1952653 ICCB4_000076 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D11 compound treatment 0.384 0.0141 1.13 0.369 0.0171 1.55 1.8961 0.9882 1952654 ICCB4_000077 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D12 compound treatment 0.382 0.0121 0.97 0.373 0.0211 1.91 2.039 0.9507 1952655 ICCB4_000078 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D13 compound treatment 0.389 0.0191 1.54 0.376 0.0241 2.18 2.6301 0.9851 1952656 ICCB4_000079 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D14 compound treatment 0.385 0.0151 1.21 0.386 0.0341 3.09 3.0442 0.9165 1952657 ICCB4_000080 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D15 compound treatment 0.371 0.00107 0.09 0.369 0.0171 1.55 1.1559 0.7452 1952658 ICCB4_000081 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D16 compound treatment 0.379 0.00907 0.73 0.371 0.0191 1.73 1.7398 0.9264 1952659 ICCB4_000082 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D17 compound treatment 0.386 0.0161 1.29 0.381 0.0291 2.64 2.7802 0.9462 1952660 ICCB4_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D18 compound treatment 0.381 0.0111 0.89 0.369 0.0171 1.55 1.7253 0.9655 1952661 ICCB4_000084 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D19 compound treatment 0.378 0.00807 0.65 0.376 0.0241 2.18 2.0038 0.8793 1952662 ICCB4_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D20 compound treatment 0.405 0.0351 2.82 0.386 0.0341 3.09 4.183 0.999 1952663 ICCB4_000086 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D21 compound treatment 0.376 0.00607 0.49 0.357 0.00506 0.46 0.6704 0.9995 1952664 ICCB4_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D22 compound treatment 0.395 0.0251 2.02 0.381 0.0291 2.64 3.2927 0.9913 1952665 ICCB4_000088 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D23 mock treatment 0.368 -0.00193 -0.16 0.355 0.00306 0.28 0.0865 0.2714 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 D24 positive control 0.094 -0.276 -22.22 0.087 -0.265 -24.05 -32.7169 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E01 compound treatment 0.379 0.00907 0.73 0.367 0.0151 1.37 1.4831 0.9568 1952666 ICCB4_000089 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E02 compound treatment 0.373 0.00307 0.25 0.37 0.0181 1.64 1.334 0.8045 1952667 ICCB4_000090 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E03 compound treatment 0.383 0.0131 1.05 0.375 0.0231 2.09 2.2243 0.9493 1952668 ICCB4_000091 C[C@H](NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E04 compound treatment 0.377 0.00707 0.57 0.368 0.0161 1.46 1.4334 0.9158 1952669 ICCB4_000092 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E05 compound treatment 0.378 0.00807 0.65 0.371 0.0191 1.73 1.6829 0.9105 1952670 ICCB4_000093 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E06 compound treatment 0.375 0.00507 0.41 0.364 0.0121 1.09 1.0627 0.9095 1952671 ICCB4_000094 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E07 compound treatment 0.379 0.00907 0.73 0.378 0.0261 2.37 2.1891 0.8842 1952672 ICCB4_000095 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E08 compound treatment 0.373 0.00307 0.25 0.375 0.0231 2.09 1.6549 0.7851 1952673 ICCB4_000096 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E09 compound treatment 0.374 0.00407 0.33 0.367 0.0151 1.37 1.1983 0.8524 1952674 ICCB4_000097 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E10 compound treatment 0.384 0.0141 1.13 0.368 0.0161 1.46 1.8319 0.9922 1952675 ICCB4_000098 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E11 compound treatment 0.386 0.0161 1.29 0.37 0.0181 1.64 2.0742 0.9931 1952676 ICCB4_000099 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccc4OCOc4c3)O2)O1)OC(=O)NCCc5ccc(F)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E12 compound treatment 0.395 0.0251 2.02 0.283 -0.0689 -6.26 -2.9974 -0.4559 1952677 ICCB4_000100 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E13 compound treatment 0.38 0.0101 0.81 0.362 0.0101 0.91 1.2191 0.9982 1952678 ICCB4_000101 COC(=O)CC(COc1ccccc1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E14 compound treatment 0.368 -0.00193 -0.16 0.355 0.00306 0.28 0.0865 0.2714 1952679 ICCB4_000102 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E15 compound treatment 0.379 0.00907 0.73 0.34 -0.0119 -1.08 -0.2499 -0.1913 1952680 ICCB4_000103 Cc1ccccc1Sc2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E16 compound treatment 0.369 -9.33E-4 -0.08 0.353 0.00106 0.1 0.0151 0.1231 1952681 ICCB4_000104 Cc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E17 compound treatment 0.371 0.00107 0.09 0.355 0.00306 0.28 0.2573 0.8843 1952682 ICCB4_000105 O=c1cc(Sc2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E18 compound treatment 0.377 0.00707 0.57 0.355 0.00306 0.28 0.5989 0.9457 1513117 ICCB4_000106 Clc1ccc(Sc2cc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E19 compound treatment 0.36 -0.00993 -0.8 0.347 -0.00494 -0.45 -0.8825 -0.9625 1952683 ICCB4_000107 CC(C)(C)[Si](C)(C)*c1ccccc1C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E20 compound treatment 0.376 0.00607 0.49 0.369 0.0171 1.55 1.4406 0.8871 3107306 ICCB4_000108 CCC(C)c1ccc2ccccc2c1.COC=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E21 compound treatment 0.368 -0.00193 -0.16 0.355 0.00306 0.28 0.0865 0.2714 1952686 ICCB4_000109 CCc1ccccc1C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E22 compound treatment 0.368 -0.00193 -0.16 0.343 -0.00894 -0.81 -0.6837 -0.8277 1952687 ICCB4_000110 CCCCSc1cc(=O)oc2ccc(C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E23 mock treatment 0.376 0.00607 0.49 0.354 0.00206 0.19 0.4778 0.9133 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 E24 positive control 0.096 -0.274 -22.06 0.089 -0.263 -23.87 -32.4747 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F01 compound treatment 0.367 -0.00293 -0.24 0.35 -0.00194 -0.18 -0.2914 -0.9894 1952688 ICCB4_000111 Cc1ccc(cc1)C(=O)c2ccccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F02 compound treatment 0.38 0.0101 0.81 0.362 0.0101 0.91 1.2191 0.9982 1952689 ICCB4_000112 Cc1ccccc1c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F03 compound treatment 0.377 0.00707 0.57 0.369 0.0171 1.55 1.4975 0.9076 1952690 ICCB4_000113 COC(=O)CC(C(=O)OC)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F04 compound treatment 0.373 0.00307 0.25 0.369 0.0171 1.55 1.2698 0.8096 1952691 ICCB4_000114 O=c1cc(c2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F05 compound treatment 0.382 0.0121 0.97 0.362 0.0101 0.91 1.3329 0.9995 3006340 ICCB4_000115 Cc1cc(=O)oc2ccccc12.Fc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F06 compound treatment 0.373 0.00307 0.25 0.359 0.00706 0.64 0.6279 0.914 1952692 ICCB4_000116 Cc1ccccc1C(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F07 compound treatment 0.38 0.0101 0.81 0.353 0.00106 0.1 0.6414 0.7857 1952693 ICCB4_000117 Cc1ccc2oc(=O)cc(Sc3ccccc3C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F08 compound treatment 0.379 0.00907 0.73 0.364 0.0121 1.09 1.2905 0.9806 1952682 ICCB4_000118 O=c1cc(Sc2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F09 compound treatment 0.373 0.00307 0.25 0.369 0.0171 1.55 1.2698 0.8096 1952694 ICCB4_000119 CCCC(=O)c1ccccc1O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F10 compound treatment 0.392 0.0221 1.78 0.355 0.00306 0.28 1.4531 0.8079 1952695 ICCB4_000120 COc1ccc2c(Sc3ccc(Cl)cc3)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F11 compound treatment 0.372 0.00207 0.17 0.362 0.0101 0.91 0.7635 0.8224 1216338 ICCB4_000121 O=c1cc(SCc2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F12 compound treatment 0.367 -0.00293 -0.24 0.361 0.00906 0.82 0.4147 0.4845 1952696 ICCB4_000122 Cc1ccc2oc(=O)cc(Sc3ccc(Cl)cc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F13 compound treatment 0.38 0.0101 0.81 0.355 0.00306 0.28 0.7698 0.8982 1952697 ICCB4_000123 O=c1cc(c2cccs2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F14 compound treatment 0.387 0.0171 1.37 0.363 0.0111 1.0 1.6818 0.9881 1952698 ICCB4_000124 COc1ccc2c(Sc3ccccc3C)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F15 compound treatment 0.373 0.00307 0.25 0.366 0.0141 1.28 1.0772 0.8285 1952699 ICCB4_000125 COc1ccc2c(Sc3ccccc3)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F16 compound treatment 0.379 0.00907 0.73 0.366 0.0141 1.28 1.4189 0.9649 3107307 ICCB4_000126 COC=O.COC(CCCC[N+](=O)[O-])CC(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F17 compound treatment 0.377 0.00707 0.57 0.367 0.0151 1.37 1.3692 0.9245 1952701 ICCB4_000127 COC(=O)CC(C(=O)C=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F18 compound treatment 0.372 0.00207 0.17 0.353 0.00106 0.1 0.1859 0.9663 1454292 ICCB4_000128 COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F19 compound treatment 0.369 -9.33E-4 -0.08 0.346 -0.00594 -0.54 -0.4342 -0.798 1952702 ICCB4_000129 CCCCSc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F20 compound treatment 0.371 0.00107 0.09 0.353 0.00106 0.1 0.1289 0.9983 1952703 ICCB4_000130 COc1ccccc1c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F21 compound treatment 0.374 0.00407 0.33 0.371 0.0191 1.73 1.4551 0.8263 1952704 ICCB4_000131 COC(CC(=O)OC)c1ccc(OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F22 compound treatment 0.367 -0.00293 -0.24 0.359 0.00706 0.64 0.2863 0.419 1952705 ICCB4_000132 Cc1ccccc1C(=O)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F23 mock treatment 0.377 0.00707 0.57 0.359 0.00706 0.64 0.8557 0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 F24 positive control 0.095 -0.275 -22.14 0.088 -0.264 -23.96 -32.5958 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G01 compound treatment 0.372 0.00207 0.17 0.347 -0.00494 -0.45 -0.1992 -0.4167 3107308 ICCB4_000133 Cc1cc(=O)oc2ccccc12.FC(F)(F)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G02 compound treatment 0.374 0.00407 0.33 0.362 0.0101 0.91 0.8774 0.9043 1011613 ICCB4_000134 Oc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G03 compound treatment 0.368 -0.00193 -0.16 0.362 0.0101 0.91 0.5358 0.5782 1952690 ICCB4_000135 COC(=O)CC(C(=O)OC)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G04 compound treatment 0.378 0.00807 0.65 0.359 0.00706 0.64 0.9126 1.0 1952706 ICCB4_000136 Cc1ccccc1C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G05 compound treatment 0.38 0.0101 0.81 0.369 0.0171 1.55 1.6684 0.9544 1952707 ICCB4_000137 CCCCSc1cc(=O)oc2cc(OC)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G06 compound treatment 0.368 -0.00193 -0.16 0.363 0.0111 1.0 0.6 0.5904 1004725 ICCB4_000138 COc1ccc(cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G07 compound treatment 0.378 0.00807 0.65 0.35 -0.00194 -0.18 0.335 0.4977 1952706 ICCB4_000139 Cc1ccccc1C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G08 compound treatment 0.377 0.00707 0.57 0.355 0.00306 0.28 0.5989 0.9457 1041165 ICCB4_000140 Cc1ccccc1C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G09 compound treatment 0.373 0.00307 0.25 0.352 6.25E-5 0.01 0.1786 0.7232 1952708 ICCB4_000141 COc1ccc2c(cc(=O)oc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G10 compound treatment 0.373 0.00307 0.25 0.361 0.00906 0.82 0.7563 0.8806 3107354 ICCB4_000142 CCOP(=O)(O)OCC.COc1ccc2c(C)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G11 compound treatment 0.37 6.67E-5 0.01 0.354 0.00206 0.19 0.1362 0.7271 3005721 ICCB4_000143 CCOP(=O)(O)OCC.Cc1ccc2oc(=O)cc(C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G12 compound treatment 0.372 0.00207 0.17 0.354 0.00206 0.19 0.2501 0.9983 1952710 ICCB4_000144 O=c1cc(C#Cc2ccccc2OCc3ccccc3)c4ccccc4o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G13 compound treatment 0.384 0.0141 1.13 0.362 0.0101 0.91 1.4468 0.9943 1952711 ICCB4_000145 Cc1cc(F)ccc1c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G14 compound treatment 0.371 0.00107 0.09 0.357 0.00506 0.46 0.3857 0.825 3107355 ICCB4_000146 Cc1cc(=O)oc2ccccc12.OP(=O)(Oc1ccccc1)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G15 compound treatment 0.357 -0.0129 -1.04 0.32 -0.0319 -2.9 -2.7863 -0.9045 802898 ICCB4_000147 Cc1ccccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G16 compound treatment 0.35 -0.0199 -1.61 0.332 -0.0199 -1.81 -2.4147 -0.9982 ICCB4_000148 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G17 compound treatment 0.392 0.0221 1.78 0.375 0.0231 2.09 2.7368 0.9967 1952713 ICCB4_000149 COc1cc(C=O)cc(I)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G18 compound treatment 0.37 6.67E-5 0.01 0.361 0.00906 0.82 0.5855 0.7117 1952714 ICCB4_000150 O=c1cc(CCCC#N)c2ccccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G19 compound treatment 0.371 0.00107 0.09 0.35 -0.00194 -0.18 -0.0636 -0.3251 1952697 ICCB4_000151 O=c1cc(c2cccs2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G20 compound treatment 0.37 6.67E-5 0.01 0.355 0.00306 0.28 0.2004 0.7206 1952715 ICCB4_000152 O=c1cc(C2CCCCC2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G21 compound treatment 0.371 0.00107 0.09 0.361 0.00906 0.82 0.6424 0.7767 1952716 ICCB4_000153 CCCc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G22 compound treatment 0.374 0.00407 0.33 0.364 0.0121 1.09 1.0058 0.8801 1952699 ICCB4_000154 COc1ccc2c(Sc3ccccc3)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G23 mock treatment 0.372 0.00207 0.17 0.361 0.00906 0.82 0.6994 0.8333 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 G24 positive control 0.095 -0.275 -22.14 0.088 -0.264 -23.96 -32.5958 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H01 compound treatment 0.378 0.00807 0.65 0.363 0.0111 1.0 1.1694 0.9778 3107356 ICCB4_000155 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H02 compound treatment 0.37 6.67E-5 0.01 0.365 0.0131 1.19 0.8422 0.7103 1952717 ICCB4_000156 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#Cc2ccccc2)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H03 compound treatment 0.375 0.00507 0.41 0.346 -0.00594 -0.54 -0.0926 -0.137 1952718 ICCB4_000157 CCCN/C(=C\1/C(=O)Oc2ccccc12)/c3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H04 compound treatment 0.379 0.00907 0.73 0.357 0.00506 0.46 0.8412 0.9751 1952719 ICCB4_000158 Br/C(=C(\Br)/C(=O)NCc1ccccc1)/C(=O)NCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H05 compound treatment 0.377 0.00707 0.57 0.361 0.00906 0.82 0.9841 0.9838 1952720 ICCB4_000159 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC(O)(c2ccccc2)c3ccccc3)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H06 compound treatment 0.371 0.00107 0.09 0.349 -0.00294 -0.27 -0.1278 -0.4562 1952721 ICCB4_000160 CC#CCOC(=O)c1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H07 compound treatment 0.38 0.0101 0.81 0.367 0.0151 1.37 1.54 0.9689 1952722 ICCB4_000161 OC(=O)c1cc2ccccc2c(I)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H08 compound treatment 0.378 0.00807 0.65 0.361 0.00906 0.82 1.041 0.9932 1952723 ICCB4_000162 COc1cc(CO[Si](C)(C)C(C)(C)C)cc2/C(=C(\c3ccccc3)/c4ccc(O)cc4)/C(=O)Oc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H09 compound treatment 0.38 0.0101 0.81 0.364 0.0121 1.09 1.3474 0.9891 1952724 ICCB4_000163 OC(=O)c1cc(Cl)c(O)c(I)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H10 compound treatment 0.376 0.00607 0.49 0.369 0.0171 1.55 1.4406 0.8871 1952725 ICCB4_000164 Oc1cc(Cl)ccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H11 compound treatment 0.374 0.00407 0.33 0.351 -9.38E-4 -0.09 0.1714 0.5065 1952726 ICCB4_000165 CCc1cc(OC)c(OC(=O)c2ccc(OC)cc2)c(C#CC(O)C(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H12 compound treatment 0.367 -0.00293 -0.24 0.327 -0.0249 -2.26 -1.7676 -0.7767 1952727 ICCB4_000166 COC(=O)c1cc2/C(=C(\c3ccccc3)/c4ccc(OC)cc4)/C(=O)Cc2c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H13 compound treatment 0.333 -0.0369 -2.97 0.305 -0.0469 -4.26 -5.1157 -0.9846 3107360 ICCB4_000167 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H14 compound treatment 0.356 -0.0139 -1.12 0.326 -0.0259 -2.35 -2.4582 -0.9425 1952728 ICCB4_000168 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H15 compound treatment 0.375 0.00507 0.41 0.341 -0.0109 -0.99 -0.4135 -0.3853 1952729 ICCB4_000169 CCCCC#Cc1cc(=O)oc2ccc(CCCC)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H16 compound treatment 0.362 -0.00793 -0.64 0.337 -0.0149 -1.36 -1.4105 -0.941 1952730 ICCB4_000170 O=c1cc(Cc2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H17 compound treatment 0.38 0.0101 0.81 0.356 0.00406 0.37 0.834 0.9364 1952731 ICCB4_000171 Cc1ccc2oc(=O)cc(Cc3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H18 compound treatment 0.391 0.0211 1.7 0.386 0.0341 3.09 3.3859 0.9601 1952732 ICCB4_000172 COc1ccc2C(=CC(=O)Cc2c1)C(=C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H19 compound treatment 0.371 0.00107 0.09 0.344 -0.00794 -0.72 -0.4487 -0.6184 1952733 ICCB4_000173 O=C(OCCc1ccccc1)Oc2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H20 compound treatment 0.378 0.00807 0.65 0.358 0.00606 0.55 0.8484 0.9966 3107361 ICCB4_000174 Cc1ccc(cc1)S(=O)(=O)O.Cc1ccc2oc(=O)cc(C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H21 compound treatment 0.371 0.00107 0.09 0.356 0.00406 0.37 0.3215 0.8491 1952716 ICCB4_000175 CCCc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H22 compound treatment 0.39 0.0201 1.62 0.374 0.0221 2.0 2.5587 0.9943 1952734 ICCB4_000176 Clc1ccc2oc(=O)cc(c3cccs3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H23 mock treatment 0.373 0.00307 0.25 0.363 0.0111 1.0 0.8847 0.8555 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 H24 positive control 0.098 -0.272 -21.9 0.089 -0.263 -23.87 -32.3608 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I01 compound treatment 0.367 -0.00293 -0.24 0.345 -0.00694 -0.63 -0.6123 -0.9104 1952735 ICCB4_000177 COc1cc(cc(I)c1C)C(C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I02 compound treatment 0.374 0.00407 0.33 0.36 0.00806 0.73 0.7491 0.9342 1952736 ICCB4_000178 CCCCC#Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I03 compound treatment 0.378 0.00807 0.65 0.371 0.0191 1.73 1.6829 0.9105 1952737 ICCB4_000179 C[Si](C)(C)C#Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I04 compound treatment 0.37 6.67E-5 0.01 0.362 0.0101 0.91 0.6497 0.7113 1952738 ICCB4_000180 O=c1cc(C#CCCC#N)c2ccccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I05 compound treatment 0.378 0.00807 0.65 0.37 0.0181 1.64 1.6187 0.9178 1952739 ICCB4_000181 ClCCC#Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I06 compound treatment 0.376 0.00607 0.49 0.366 0.0141 1.28 1.248 0.9131 1952691 ICCB4_000182 O=c1cc(c2ccccc2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I07 compound treatment 0.375 0.00507 0.41 0.349 -0.00294 -0.27 0.1 0.2051 1952740 ICCB4_000183 CC(=O)CC(c1ccccc1)c2c(OS(=O)(=O)c3ccc(C)cc3)c4ccccc4oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I08 compound treatment 0.38 0.0101 0.81 0.359 0.00706 0.64 1.0265 0.9932 1952741 ICCB4_000184 Brc1ccc(C#Cc2cc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I09 compound treatment 0.39 0.0201 1.62 0.354 0.00206 0.19 1.275 0.7838 3005723 ICCB4_000185 Cc1ccccc1.Cc1ccc(cc1)S(=O)(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I10 compound treatment 0.379 0.00907 0.73 0.369 0.0171 1.55 1.6114 0.9411 1952742 ICCB4_000186 CCCCCCCCC#Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I11 compound treatment 0.374 0.00407 0.33 0.364 0.0121 1.09 1.0058 0.8801 1952743 ICCB4_000187 COC(=O)/C=C/c1cc(I)c(C)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I12 compound treatment 0.373 0.00307 0.25 0.356 0.00406 0.37 0.4354 0.981 1952744 ICCB4_000188 Cc1ccc2oc(=O)cc(c3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I13 compound treatment 0.379 0.00907 0.73 0.356 0.00406 0.37 0.777 0.95 1952745 ICCB4_000189 COc1ccc(cc1)c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I14 compound treatment 0.375 0.00507 0.41 0.342 -0.00994 -0.9 -0.3493 -0.3529 1952746 ICCB4_000190 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I15 compound treatment 0.357 -0.0129 -1.04 0.333 -0.0189 -1.72 -1.9519 -0.9712 3005760 ICCB4_000191 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I16 compound treatment 0.366 -0.00393 -0.32 0.357 0.00506 0.46 0.101 0.1809 3005761 ICCB4_000192 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I17 compound treatment 0.396 0.0261 2.1 0.347 -0.00494 -0.45 1.1673 0.5439 1089965 ICCB4_000193 COC(=O)c1ccc(OC)c(I)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I18 compound treatment 0.365 -0.00493 -0.4 0.332 -0.0199 -1.81 -1.5606 -0.8423 1952748 ICCB4_000194 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I19 compound treatment 0.372 0.00207 0.17 0.36 0.00806 0.73 0.6352 0.8463 3005762 ICCB4_000195 Cc1ccc(cc1)[N+](=O)[O-].Cc1ccc(cc1)S(=O)(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I20 compound treatment 0.352 -0.0179 -1.44 0.341 -0.0109 -0.99 -1.7232 -0.9833 1107217 ICCB4_000196 Cc1cccnc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I21 compound treatment 0.385 0.0151 1.21 0.365 0.0131 1.19 1.6963 0.9999 3005761 ICCB4_000197 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I22 compound treatment 0.362 -0.00793 -0.64 0.371 0.0191 1.73 0.7718 0.4184 1952749 ICCB4_000198 OCCC#Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I23 mock treatment 0.377 0.00707 0.57 0.354 0.00206 0.19 0.5348 0.8927 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 I24 positive control 0.096 -0.274 -22.06 0.089 -0.263 -23.87 -32.4747 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J01 compound treatment 0.395 0.0251 2.02 0.365 0.0131 1.19 2.2657 0.9678 3005763 ICCB4_000199 CCCCc1cc(=O)oc2ccc(C)cc12.C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J02 compound treatment 0.376 0.00607 0.49 0.371 0.0191 1.73 1.569 0.8726 1952752 ICCB4_000200 CCCCC#Cc1cc(=O)oc2cc(OC)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J03 compound treatment 0.37 6.67E-5 0.01 0.369 0.0171 1.55 1.099 0.7096 1952753 ICCB4_000201 CCCCC#Cc1cc(=O)oc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J04 compound treatment 0.423 0.0531 4.27 0.39 0.0381 3.45 5.4647 0.9944 1952754 ICCB4_000202 CCCCC#Cc1c(C#CCCCC)c2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J05 compound treatment 0.436 0.0661 5.32 0.407 0.0551 5.0 7.2961 0.9995 3005764 ICCB4_000203 COc1ccc2c(C)cc(=O)oc2c1.Cc1ccc(cc1)S(=O)(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J06 compound treatment 0.401 0.0311 2.5 0.359 0.00706 0.64 2.2223 0.8605 1952705 ICCB4_000204 Cc1ccccc1C(=O)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J07 compound treatment 0.375 0.00507 0.41 0.348 -0.00394 -0.36 0.0358 0.0659 3107360 ICCB4_000205 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J08 compound treatment 0.392 0.0221 1.78 0.362 0.0101 0.91 1.9024 0.9522 1952755 ICCB4_000206 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J09 compound treatment 0.453 0.0831 6.69 0.438 0.0861 7.81 10.2538 0.997 1952756 ICCB4_000207 COc1cc(CO[Si](C)(C)C(C)(C)C)cc2c3C(=O)OC(c3oc12)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J10 compound treatment 0.371 0.00107 0.09 0.343 -0.00894 -0.81 -0.5129 -0.6287 1952757 ICCB4_000208 CC(C)CC1(C)OC(=O)c2c1oc3c(Cl)cc(cc23)C(=O)NCCO[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J11 compound treatment 0.354 -0.0159 -1.28 0.339 -0.0129 -1.17 -1.7377 -0.999 1952005 ICCB4_000209 COC(=O)c1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J12 compound treatment 0.403 0.0331 2.66 0.316 -0.0359 -3.26 -0.4238 -0.1006 1952758 ICCB4_000210 CC(C)CC1(C)OC(=O)c2c1oc3c(cc(cc23)c4ccc(F)c(F)c4)C(=O)NCCO[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J13 compound treatment 0.408 0.0381 3.07 0.411 0.0591 5.36 5.9585 0.9648 1952759 ICCB4_000211 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CCO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J14 compound treatment 0.369 -9.33E-4 -0.08 0.35 -0.00194 -0.18 -0.1775 -0.9281 1952760 ICCB4_000212 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J15 compound treatment 0.383 0.0131 1.05 0.38 0.0281 2.55 2.5452 0.9235 1952761 ICCB4_000213 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J16 compound treatment 0.407 0.0371 2.98 0.406 0.0541 4.91 5.5806 0.9716 1952762 ICCB4_000214 COc1cc(CO[Si](C)(C)C(C)(C)C)cc2/C(=C(\c3ccccc3)/c4ccc(cc4)C(=O)C)/C(=O)Oc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J17 compound treatment 0.358 -0.0119 -0.96 0.338 -0.0139 -1.27 -1.5741 -0.9908 1952763 ICCB4_000215 CCc1cc(OC)c2oc3c(C(=O)OC3(C)c4ccccc4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J18 compound treatment 0.374 0.00407 0.33 0.376 0.0241 2.18 1.776 0.8041 1952764 ICCB4_000216 CCc1cc(OC)c2oc3c(C(=O)OC43CC5CC6CCc7ccc(OC)cc7C6CC5C4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J19 compound treatment 0.367 -0.00293 -0.24 0.346 -0.00594 -0.54 -0.5481 -0.9315 1952765 ICCB4_000217 COC(=O)/C=C/c1cc2C(=C(Cc2c(OC)c1)c3ccccc3)C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J20 compound treatment 0.405 0.0351 2.82 0.376 0.0241 2.18 3.5412 0.9919 1952766 ICCB4_000218 CCc1cc2/C(=C(/c3ccc(OC)cc3)\c4ccc(OC)c(OC)c4)/C(=O)Cc2c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J21 compound treatment 0.375 0.00507 0.41 0.335 -0.0169 -1.54 -0.7986 -0.5021 1952767 ICCB4_000219 O=C1Oc2ccccc2C1=C(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J22 compound treatment 0.384 0.0141 1.13 0.352 6.25E-5 0.01 0.805 0.7106 1952768 ICCB4_000220 CCc1cc(OC)c2oc3c(C(=O)OC43CCCC4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J23 mock treatment 0.354 -0.0159 -1.28 0.344 -0.00794 -0.72 -1.4167 -0.9628 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 J24 positive control 0.097 -0.273 -21.98 0.089 -0.263 -23.87 -32.4177 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K01 compound treatment 0.384 0.0141 1.13 0.363 0.0111 1.0 1.511 0.9982 1952769 ICCB4_000221 CCc1cc(OC)c2oc3C(OC(=O)c3c2c1)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K02 compound treatment 0.382 0.0121 0.97 0.358 0.00606 0.55 1.0762 0.9637 1952770 ICCB4_000222 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K03 compound treatment 0.387 0.0171 1.37 0.361 0.00906 0.82 1.5535 0.9699 1952771 ICCB4_000223 CC(C)CCC1(C)OC(=O)c2c1oc3c(CCO[Si](C)(C)C(C)(C)C)cc(cc23)c4cc(F)cc(F)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K04 compound treatment 0.419 0.0491 3.95 0.401 0.0491 4.45 5.943 0.9982 1952772 ICCB4_000224 CCCNC(=O)c1cc(cc2c3C(=O)OC(C)(CC(C)C)c3oc12)c4cc(F)cc(F)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K05 compound treatment 0.381 0.0111 0.89 0.361 0.00906 0.82 1.2118 0.9992 1952767 ICCB4_000225 O=C1Oc2ccccc2C1=C(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K06 compound treatment 0.37 6.67E-5 0.01 0.387 0.0351 3.18 2.2543 0.7083 1952773 ICCB4_000226 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K07 compound treatment 0.188 -0.182 -14.65 0.263 -0.0889 -8.07 -16.0679 -0.9606 1952774 ICCB4_000227 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(Cl)c2oc3c(C(=O)OC43CCCC4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K08 compound treatment 0.364 -0.00593 -0.48 0.357 0.00506 0.46 -0.0129 -0.0195 1952775 ICCB4_000228 CC(C)C1OC(=O)c2c1oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K09 compound treatment 0.391 0.0211 1.7 0.368 0.0161 1.46 2.2305 0.9972 1952776 ICCB4_000229 FC(F)(F)c1ccc(cc1)/C(=C/2\C(=O)Oc3ccccc23)/c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K10 compound treatment 0.373 0.00307 0.25 0.367 0.0151 1.37 1.1414 0.8215 1952777 ICCB4_000230 Cc1ccc(cc1)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K11 compound treatment 0.389 0.0191 1.54 0.376 0.0241 2.18 2.6301 0.9851 1952778 ICCB4_000231 O=C1OC(c2oc3ccccc3c12)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K12 compound treatment 0.455 0.0851 6.85 0.412 0.0601 5.45 8.6989 0.9936 1952779 ICCB4_000232 COC(=O)/C=C/c1cc(OC)c(Oc2ccccc2)c(C#C[Si](C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K13 compound treatment 0.374 0.00407 0.33 0.357 0.00506 0.46 0.5565 0.9862 1952768 ICCB4_000233 CCc1cc(OC)c2oc3c(C(=O)OC43CCCC4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K14 compound treatment 0.376 0.00607 0.49 0.368 0.0161 1.46 1.3764 0.8951 1952780 ICCB4_000234 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K15 compound treatment 0.353 -0.0169 -1.36 0.319 -0.0329 -2.99 -3.0783 -0.9368 1952781 ICCB4_000235 CCc1cc2/C(=C(/c3ccccc3)\c4ccc(cc4)C(=O)C)/C(=O)Oc2c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K16 compound treatment 0.385 0.0151 1.21 0.363 0.0111 1.0 1.568 0.9956 1952782 ICCB4_000236 COc1ccc(cc1)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K17 compound treatment 0.379 0.00907 0.73 0.374 0.0221 2.0 1.9323 0.9065 1952003 ICCB4_000237 COC(=O)/C=C/c1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K18 compound treatment 0.36 -0.00993 -0.8 0.336 -0.0159 -1.45 -1.5886 -0.961 3107406 ICCB4_000238 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K19 compound treatment 0.366 -0.00393 -0.32 0.339 -0.0129 -1.17 -1.0544 -0.8668 3005767 ICCB4_000239 CCc1cc(OC)c2oc(c(C)c2c1)c3ccc(Oc4ccccc4)c(OC)c3.COc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K20 compound treatment 0.355 -0.0149 -1.2 0.347 -0.00494 -0.45 -1.1672 -0.9095 1952785 ICCB4_000240 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K21 compound treatment 0.347 -0.0229 -1.85 0.332 -0.0199 -1.81 -2.5855 -0.9999 1952786 ICCB4_000241 COC(=O)/C=C/c1cc(OC)c2oc(c(c3ccc(C)cc3)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K22 compound treatment 0.386 0.0161 1.29 0.384 0.0321 2.91 2.9728 0.9334 1952787 ICCB4_000242 COC(=O)/C=C/c1cc(OC)c2oc(c(c3ccc(cc3)C(=O)C)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K23 mock treatment 0.372 0.00207 0.17 0.351 -9.38E-4 -0.09 0.0575 0.3076 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 K24 positive control 0.099 -0.271 -21.82 0.089 -0.263 -23.87 -32.3038 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L01 compound treatment 0.374 0.00407 0.33 0.35 -0.00194 -0.18 0.1072 0.2884 1952788 ICCB4_000243 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L02 compound treatment 0.372 0.00207 0.17 0.372 0.0201 1.82 1.4054 0.7685 1952788 ICCB4_000244 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L03 compound treatment 0.407 0.0371 2.98 0.384 0.0321 2.91 4.1685 0.9999 1952789 ICCB4_000245 COC(=O)/C=C/c1cc(C)c(OC(=O)C)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L04 compound treatment 0.359 -0.0109 -0.88 0.341 -0.0109 -0.99 -1.3246 -0.9982 1952790 ICCB4_000246 O=C(Oc1ccccc1C#Cc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L05 compound treatment 0.353 -0.0169 -1.36 0.33 -0.0219 -1.99 -2.3723 -0.9829 1952003 ICCB4_000247 COC(=O)/C=C/c1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L06 compound treatment 0.375 0.00507 0.41 0.315 -0.0369 -3.35 -2.0823 -0.6165 1952791 ICCB4_000248 COc1ccc(cc1)C(=O)c2c(oc3c(OC)cc(/C=C/C(=O)NCCO)cc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L07 compound treatment 0.382 0.0121 0.97 0.351 -9.38E-4 -0.09 0.6269 0.6427 1952792 ICCB4_000249 CC(=O)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L08 compound treatment 0.38 0.0101 0.81 0.36 0.00806 0.73 1.0907 0.9987 1952793 ICCB4_000250 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L09 compound treatment 0.418 0.0481 3.87 0.351 -9.38E-4 -0.09 2.6768 0.6914 1952794 ICCB4_000251 COc1ccc(cc1)C(=O)Oc2ccccc2C#C[Si](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L10 compound treatment 0.385 0.0151 1.21 0.365 0.0131 1.19 1.6963 0.9999 1952790 ICCB4_000252 O=C(Oc1ccccc1C#Cc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L11 compound treatment 0.404 0.0341 2.74 0.388 0.0361 3.27 4.2545 0.9961 1952795 ICCB4_000253 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L12 compound treatment 0.375 0.00507 0.41 0.36 0.00806 0.73 0.806 0.9619 1952796 ICCB4_000254 CCc1cc(OC)c(OC(=O)c2ccc(OC)cc2)c(C#Cc3ccc(Oc4ccccc4)c(OC)c3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L13 compound treatment 0.384 0.0141 1.13 0.374 0.0221 2.0 2.2171 0.9636 1952797 ICCB4_000255 CCc1cc(OC)c2oc(c(c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L14 compound treatment 0.377 0.00707 0.57 0.328 -0.0239 -2.17 -1.134 -0.5049 1952798 ICCB4_000256 COC(=O)/C=C/c1c(OC)ccc2cc(oc12)c3ccc(C)c(OC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L15 compound treatment 0.365 -0.00493 -0.4 0.353 0.00106 0.1 -0.2127 -0.5203 1952799 ICCB4_000257 COc1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L16 compound treatment 0.362 -0.00793 -0.64 0.345 -0.00694 -0.63 -0.897 -1.0 1952800 ICCB4_000258 COc1ccc(cc1)C(=O)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L17 compound treatment 0.383 0.0131 1.05 0.374 0.0221 2.0 2.1601 0.9549 1952801 ICCB4_000259 Oc1ccccc1C#Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L18 compound treatment 0.37 6.67E-5 0.01 0.347 -0.00494 -0.45 -0.3131 -0.6986 1952802 ICCB4_000260 COc1ccc(cc1)C(=O)Oc2c(OC)cc(CO[Si](C)(C)C(C)(C)C)cc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L19 compound treatment 0.383 0.0131 1.05 0.363 0.0111 1.0 1.4541 0.9997 1952803 ICCB4_000261 COC(=O)c1cc(OC)c(O)c(C#Cc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L20 compound treatment 0.372 0.00207 0.17 0.354 0.00206 0.19 0.2501 0.9983 1952761 ICCB4_000262 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L21 compound treatment 0.371 0.00107 0.09 0.359 0.00706 0.64 0.514 0.7947 1952804 ICCB4_000263 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L22 compound treatment 0.394 0.0241 1.94 0.377 0.0251 2.27 2.979 0.9968 1952805 ICCB4_000264 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L23 mock treatment 0.373 0.00307 0.25 0.356 0.00406 0.37 0.4354 0.981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 L24 positive control 0.097 -0.273 -21.98 0.09 -0.262 -23.78 -32.3535 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M01 compound treatment 0.371 0.00107 0.09 0.35 -0.00194 -0.18 -0.0636 -0.3251 1952036 ICCB4_000265 COC(=O)/C=C/c1cc(OC)c2oc(c(C(=O)c3ccc(cc3)C(F)(F)F)c2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M02 compound treatment 0.358 -0.0119 -0.96 0.333 -0.0189 -1.72 -1.895 -0.9622 1952806 ICCB4_000266 O=CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M03 compound treatment 0.287 -0.0829 -6.68 0.288 -0.0639 -5.8 -8.8261 -0.9976 1952807 ICCB4_000267 COc1cc(CO[Si](C)(C)C(C)(C)C)cc2cc(oc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M04 compound treatment 0.344 -0.0259 -2.09 0.337 -0.0149 -1.36 -2.4354 -0.9781 1952808 ICCB4_000268 CCCCCc1cc2ccccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M05 compound treatment 0.345 -0.0249 -2.01 0.33 -0.0219 -1.99 -2.8278 -1.0 1952809 ICCB4_000269 CC(=O)Oc1ccccc1C#Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M06 compound treatment 0.367 -0.00293 -0.24 0.35 -0.00194 -0.18 -0.2914 -0.9894 1952810 ICCB4_000270 CC(=O)Oc1c(Cl)cc(cc1C#CC2(O)CCCC2)C(=O)NCCO[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M07 compound treatment 0.361 -0.00893 -0.72 0.339 -0.0129 -1.17 -1.3391 -0.9723 1952811 ICCB4_000271 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M08 compound treatment 0.423 0.0531 4.27 0.403 0.0511 4.64 6.2991 0.9992 1952812 ICCB4_000272 COc1ccc(cc1)/C(=C/2\C(=O)Oc3c2cc(CO[Si](C)(C)C(C)(C)C)cc3OC)/c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M09 compound treatment 0.37 6.67E-5 0.01 0.352 6.25E-5 0.01 0.0078 0.9996 1952813 ICCB4_000273 OCCCC#Cc1cc(O)cc(Cl)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M10 compound treatment 0.36 -0.00993 -0.8 0.33 -0.0219 -1.99 -1.9737 -0.9197 1952814 ICCB4_000274 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M11 compound treatment 0.363 -0.00693 -0.56 0.354 0.00206 0.19 -0.2624 -0.4456 1952815 ICCB4_000275 CC(=O)c1ccc(O)c(C#Cc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M12 compound treatment 0.414 0.0441 3.55 0.402 0.0501 4.54 5.7225 0.9925 1952816 ICCB4_000276 CC(=O)Oc1ccccc1C#C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M13 compound treatment 0.37 6.67E-5 0.01 0.36 0.00806 0.73 0.5213 0.7123 1952817 ICCB4_000277 CC(C)CC(C)(O)C#Cc1cc(cc(Cl)c1O)C(=O)NCCO[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M14 compound treatment 0.372 0.00207 0.17 0.367 0.0151 1.37 1.0845 0.7874 1952818 ICCB4_000278 COc1cc(CCC(=O)O)cc(I)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M15 compound treatment 0.385 0.0151 1.21 0.342 -0.00994 -0.9 0.2201 0.1456 1952819 ICCB4_000279 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#Cc2ccccc2)c1OC(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M16 compound treatment 0.378 0.00807 0.65 0.347 -0.00494 -0.45 0.1424 0.1804 1952792 ICCB4_000280 CC(=O)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M17 compound treatment 0.378 0.00807 0.65 0.354 0.00206 0.19 0.5917 0.8753 1952820 ICCB4_000281 COc1ccc(cc1)C(=O)Oc2c(OC)cc(CO[Si](C)(C)C(C)(C)C)cc2C#Cc3ccc(Oc4ccccc4)c(OC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M18 compound treatment 0.368 -0.00193 -0.16 0.349 -0.00294 -0.27 -0.2986 -0.9672 1110410 ICCB4_000282 COc1ccc(C(=O)C)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M19 compound treatment 0.363 -0.00693 -0.56 0.361 0.00906 0.82 0.1869 0.188 1952821 ICCB4_000283 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M20 compound treatment 0.335 -0.0349 -2.81 0.304 -0.0479 -4.35 -5.066 -0.9777 1952822 ICCB4_000284 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1OC(=O)c3ccc(O)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M21 compound treatment 0.355 -0.0149 -1.2 0.344 -0.00794 -0.72 -1.3598 -0.97 1952823 ICCB4_000285 C#Cc1ccccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M22 compound treatment 0.418 0.0481 3.87 0.415 0.0631 5.72 6.7846 0.9818 1952799 ICCB4_000286 COc1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M23 mock treatment 0.368 -0.00193 -0.16 0.336 -0.0159 -1.45 -1.133 -0.7787 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 M24 positive control 0.098 -0.272 -21.9 0.091 -0.261 -23.69 -32.2324 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N01 compound treatment 0.36 -0.00993 -0.8 0.344 -0.00794 -0.72 -1.0751 -0.9986 1952824 ICCB4_000287 O=C(Oc1ccccc1C#Cc2ccccc2)c3ccc4ccccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N02 compound treatment 0.4 0.0301 2.42 0.385 0.0331 3.0 3.8341 0.9943 1952825 ICCB4_000288 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N03 compound treatment 0.384 0.0141 1.13 0.375 0.0231 2.09 2.2812 0.9584 1952826 ICCB4_000289 FC(F)(F)c1ccc(cc1)C(=O)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N04 compound treatment 0.389 0.0191 1.54 0.374 0.0221 2.0 2.5018 0.9914 1952827 ICCB4_000290 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc(C#CC2(O)CCCC2)c1O)c3cc(I)cc(I)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N05 compound treatment 0.352 -0.0179 -1.44 0.328 -0.0239 -2.17 -2.5576 -0.9803 1952828 ICCB4_000291 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N06 compound treatment 0.367 -0.00293 -0.24 0.345 -0.00694 -0.63 -0.6123 -0.9104 1952829 ICCB4_000292 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N07 compound treatment 0.367 -0.00293 -0.24 0.355 0.00306 0.28 0.0295 0.081 1952830 ICCB4_000293 COc1cc(CCC(=O)O)cc(I)c1OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N08 compound treatment 0.371 0.00107 0.09 0.36 0.00806 0.73 0.5782 0.7847 1952831 ICCB4_000294 CC(=O)Oc1ccc(O)cc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N09 compound treatment 0.387 0.0171 1.37 0.377 0.0251 2.27 2.5804 0.9709 1952832 ICCB4_000295 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N10 compound treatment 0.398 0.0281 2.26 0.305 -0.0469 -4.26 -1.4145 -0.2933 1952833 ICCB4_000296 [O-][N+](=O)c1ccc(cc1)c2c(oc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N11 compound treatment 0.366 -0.00393 -0.32 0.363 0.0111 1.0 0.4861 0.4616 1952834 ICCB4_000297 CC(=O)Oc1ccccc1C#C[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N12 compound treatment 0.348 -0.0219 -1.77 0.321 -0.0309 -2.81 -3.2346 -0.975 1952790 ICCB4_000298 O=C(Oc1ccccc1C#Cc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N13 compound treatment 0.354 -0.0159 -1.28 0.341 -0.0109 -0.99 -1.6093 -0.992 1952835 ICCB4_000299 Cc1cc(C)c(O)c(C#Cc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N14 compound treatment 0.379 0.00907 0.73 0.336 -0.0159 -1.45 -0.5067 -0.3127 1952836 ICCB4_000300 CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N15 compound treatment 0.48 0.11 8.86 0.449 0.0971 8.81 12.4973 1.0 1952837 ICCB4_000301 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N16 compound treatment 0.4 0.0301 2.42 0.384 0.0321 2.91 3.77 0.9958 1952838 ICCB4_000302 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N17 compound treatment 0.375 0.00507 0.41 0.357 0.00506 0.46 0.6134 0.9982 1952839 ICCB4_000303 Oc1ccccc1C#CC#Cc2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N18 compound treatment 0.265 -0.105 -8.45 0.271 -0.0809 -7.35 -11.17 -0.9976 1952840 ICCB4_000304 O(c1ccccc1)c2ccccc2C#CC#Cc3ccccc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N19 compound treatment 0.365 -0.00493 -0.4 0.353 0.00106 0.1 -0.2127 -0.5203 1952841 ICCB4_000305 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC(C)(O)c2ccccc2)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N20 compound treatment 0.359 -0.0109 -0.88 0.313 -0.0389 -3.53 -3.1218 -0.8571 1952842 ICCB4_000306 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N21 compound treatment 0.387 0.0171 1.37 0.369 0.0171 1.55 2.0669 0.9982 1952792 ICCB4_000307 CC(=O)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N22 compound treatment 0.358 -0.0119 -0.96 0.35 -0.00194 -0.18 -0.8039 -0.8229 1952843 ICCB4_000308 COc1cc(C)cc2C3C(Oc21)C4(=CC=CC=C4)OC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N23 mock treatment 0.378 0.00807 0.65 0.358 0.00606 0.55 0.8484 0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 N24 positive control 0.098 -0.272 -21.9 0.091 -0.261 -23.69 -32.2324 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O01 compound treatment 0.369 -9.33E-4 -0.08 0.354 0.00206 0.19 0.0792 0.3928 1952793 ICCB4_000309 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O02 compound treatment 0.373 0.00307 0.25 0.363 0.0111 1.0 0.8847 0.8555 1952844 ICCB4_000310 COc1cc(CO)cc2cc(oc12)C3=CC=CC3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O03 compound treatment 0.382 0.0121 0.97 0.376 0.0241 2.18 2.2315 0.9335 1952845 ICCB4_000311 COc1cc(CCCC(=O)CCO)cc(I)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O04 compound treatment 0.39 0.0201 1.62 0.38 0.0281 2.55 2.9438 0.9759 1952846 ICCB4_000312 COC(=O)/C=C/c1cc(OC)c2oc(cc2c1)c3ccc(Oc4ccccc4)c(OC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O05 compound treatment 0.351 -0.0189 -1.52 0.337 -0.0149 -1.36 -2.0368 -0.9983 1952847 ICCB4_000313 COc1cc(CCCC(=O)CCO)cc(I)c1OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O06 compound treatment 0.375 0.00507 0.41 0.343 -0.00894 -0.81 -0.2852 -0.314 1613808 ICCB4_000314 CCOC(=O)C1=C(C)N(Cc2ccccc2)C(=O)NC1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O07 compound treatment 0.374 0.00407 0.33 0.379 0.0271 2.46 1.9686 0.7943 1488843 ICCB4_000315 CCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O08 compound treatment 0.383 0.0131 1.05 0.363 0.0111 1.0 1.4541 0.9997 1665217 ICCB4_000316 CCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O09 compound treatment 0.385 0.0151 1.21 0.369 0.0171 1.55 1.9531 0.9927 1628523 ICCB4_000317 CCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O10 compound treatment 0.378 0.00807 0.65 0.365 0.0131 1.19 1.2977 0.9599 1779018 ICCB4_000318 CCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(cc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O11 compound treatment 0.378 0.00807 0.65 0.36 0.00806 0.73 0.9768 0.9982 1952848 ICCB4_000319 CN1C(=C(C(NC1=O)c2ccc(Br)cc2)C(=O)OCC=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O12 compound treatment 0.382 0.0121 0.97 0.36 0.00806 0.73 1.2046 0.9902 1952849 ICCB4_000320 CCOC(=O)C1=C(C)N(CC=C)C(=O)NC1c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O13 compound treatment 0.376 0.00607 0.49 0.363 0.0111 1.0 1.0555 0.9452 1952850 ICCB4_000321 CCCC1=C(C(NC(=O)N1C)c2ccc(Br)cc2)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O14 compound treatment 0.373 0.00307 0.25 0.366 0.0141 1.28 1.0772 0.8285 1276067 ICCB4_000322 CCOC(=O)C1=C(C)N(Cc2ccccc2)C(=O)NC1c3ccc(Br)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O15 compound treatment 0.371 0.00107 0.09 0.345 -0.00694 -0.63 -0.3845 -0.6051 1952851 ICCB4_000323 CCOC(=O)C1=C(C)N(Cc2ccccc2)C(=O)NC1c3cccc(Br)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O16 compound treatment 0.346 -0.0239 -1.93 0.335 -0.0169 -1.54 -2.4499 -0.9937 1952852 ICCB4_000324 CCOC(=O)C1=C(C)N(Cc2ccccc2)C(=O)NC1c3ccccc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O17 compound treatment 0.38 0.0101 0.81 0.366 0.0141 1.28 1.4758 0.976 1952853 ICCB4_000325 OC1C(NCc2ccccc2)C3OCC(O3)C1N=[N+]=[N-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O18 compound treatment 0.378 0.00807 0.65 0.353 0.00106 0.1 0.5275 0.8033 1952854 ICCB4_000326 OC1C(NC(=O)c2ccccc2)C3OCC(O3)C1N=[N+]=[N-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O19 compound treatment 0.67 0.3 24.16 0.648 0.296 26.87 36.0888 0.9986 1952855 ICCB4_000327 OC1C(NC(=O)Oc2ccc(cc2)[N+](=O)[O-])C3OCC(O3)C1N=[N+]=[N-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O20 compound treatment 0.368 -0.00193 -0.16 0.351 -9.38E-4 -0.09 -0.1703 -0.9596 1952856 ICCB4_000328 OC1C(NC(=O)NCc2ccccc2)C3OCC(O3)C1N=[N+]=[N-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O21 compound treatment 0.384 0.0141 1.13 0.366 0.0141 1.28 1.7036 0.9982 1952038 ICCB4_000329 CC12CCC3C(CC=C4CC(O)CCC34C)C2CC=C1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O22 compound treatment 0.386 0.0161 1.29 0.383 0.0311 2.82 2.9086 0.9376 1952857 ICCB4_000330 CC(C)C(C)/C=C/C(C)C1(C)CCC2c3ccc(CC(O)CC\C(=C\CCC21C)\C)cc3C(=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O23 mock treatment 0.356 -0.0139 -1.12 0.337 -0.0149 -1.36 -1.7521 -0.9956 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 O24 positive control 0.097 -0.273 -21.98 0.09 -0.262 -23.78 -32.3535 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P01 compound treatment 0.365 -0.00493 -0.4 0.355 0.00306 0.28 -0.0843 -0.1739 1952858 ICCB4_000331 N[C@@H](Cc1c[nH]c(F)n1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P02 compound treatment 0.367 -0.00293 -0.24 0.363 0.0111 1.0 0.543 0.5264 1952859 ICCB4_000332 COc1ccc(C/[N+](=C/C(=O)O)/[O-])cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P03 compound treatment 0.366 -0.00393 -0.32 0.374 0.0221 2.0 1.1921 0.588 1952860 ICCB4_000333 CCCCNC(=O)C1=CC2C3C(C1C(CC=C)N2C(=O)OC)C(=O)OC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P04 compound treatment 0.364 -0.00593 -0.48 0.354 0.00206 0.19 -0.2055 -0.4004 1952861 ICCB4_000334 COC(=O)/C=C\[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P05 compound treatment 0.368 -0.00193 -0.16 0.349 -0.00294 -0.27 -0.2986 -0.9672 1084394 ICCB4_000335 NC(Cc1nc[nH]c1F)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P06 compound treatment 0.48 0.11 8.86 0.461 0.109 9.9 13.2675 0.9985 1952862 ICCB4_000336 NCCc1c[nH]c(F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P07 compound treatment 0.368 -0.00193 -0.16 0.358 0.00606 0.55 0.279 0.4879 1084393 ICCB4_000337 NC(Cc1c[nH]c(F)n1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P08 compound treatment 0.372 0.00207 0.17 0.354 0.00206 0.19 0.2501 0.9983 1952863 ICCB4_000338 CO[C@H]1O[C@@H]2COC(O[C@H]2C(O)[C@H]1O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P09 compound treatment 0.37 6.67E-5 0.01 0.365 0.0131 1.19 0.8422 0.7103 1952864 ICCB4_000339 COC(=O)N1C2C#C/C=C\C#CC3C4C(COC4=O)C(=C2C3c5cc(OC)ccc15)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P10 compound treatment 0.372 0.00207 0.17 0.366 0.0141 1.28 1.0203 0.7926 1952865 ICCB4_000340 COc1ccc2ccccc2c1c3c(OC/C=C(\C)/CC/C=C(\C)/CCC(=O)O)ccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P11 compound treatment 0.376 0.00607 0.49 0.362 0.0101 0.91 0.9913 0.957 1952866 ICCB4_000341 CO[C@H]1O[C@@H]2COC(O[C@H]2[C@H](N=Nc3ccccc3)[C@H]1O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P12 compound treatment 0.376 0.00607 0.49 0.369 0.0171 1.55 1.4406 0.8871 1952867 ICCB4_000342 NCCCCC1NC(=O)C2CCCN2C(=O)C(Cc3ccccc3)NC(=O)C(Cc4ccccc4)NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P13 compound treatment 0.366 -0.00393 -0.32 0.355 0.00306 0.28 -0.0274 -0.065 1952868 ICCB4_000343 COc1ccc(cc1)[C@@H]2OC[C@@H](CC=C)[C@H](CCO)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P14 compound treatment 0.376 0.00607 0.49 0.364 0.0121 1.09 1.1197 0.9339 1952869 ICCB4_000344 COc1ccc(CO[C@@H](C[C@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H](C)C=O)[C@H]2COC(CI)C2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P15 compound treatment 0.102 -0.268 -21.58 0.097 -0.255 -23.14 -31.6195 -0.9994 1952870 ICCB4_000345 CC[C@H]1O[C@@H]2O[C@H](/C=C/C=C/C=C/c3oc(=O)cc(OC)c3C)[C@H](O)[C@]2(C)[C@@]1(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P16 compound treatment 0.361 -0.00893 -0.72 0.339 -0.0129 -1.17 -1.3391 -0.9723 1952871 ICCB4_000346 C/C(=C\CO[Si](OC(C)(C)C)(c1ccccc1)c2ccccc2)/CC/C=C(\C)/COc3ccc4ccccc4c3c5c(OC(=O)CC#N)ccc6ccccc56 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P17 compound treatment 0.377 0.00707 0.57 0.373 0.0211 1.91 1.7543 0.8794 1952872 ICCB4_000347 C[C@H](C/C=C/CCC=C)C(=O)N(C)[C@@H](C)[C@@H](O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P18 compound treatment 0.363 -0.00693 -0.56 0.368 0.0161 1.46 0.6362 0.4075 1952873 ICCB4_000348 C[C@H]1OC(C)(C)O[C@@H]1[C@@H](OC(=O)CC(Cl)(Cl)Cl)/C=C/[C@H](OC(=O)CC(Cl)(Cl)Cl)[C@H]2OC(C)(C)O[C@@H]2C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P19 compound treatment 0.366 -0.00393 -0.32 0.363 0.0111 1.0 0.4861 0.4616 1952874 ICCB4_000349 COc1ccc2ncc(cc2c1)/C(=C/CO[Si](C)(C)C(C)(C)C)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P20 compound treatment 0.364 -0.00593 -0.48 0.351 -9.38E-4 -0.09 -0.398 -0.8201 1952875 ICCB4_000350 OC(=O)C1(CCCCC1)NC(=O)c2cccc(c2F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P21 compound treatment 0.365 -0.00493 -0.4 0.359 0.00706 0.64 0.1724 0.2286 1952876 ICCB4_000351 OC(=O)c1ccc(NC(=O)c2cccc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P22 compound treatment 0.368 -0.00193 -0.16 0.363 0.0111 1.0 0.6 0.5904 1952877 ICCB4_000352 COc1cc2CCN3CCC[C@@H]4C(=NO[C@@]43c2cc1OC)c5ccc(O[Si](C)(C)C(C)(C)C)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P23 mock treatment 0.364 -0.00593 -0.48 0.352 6.25E-5 0.01 -0.3338 -0.6987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1266 P24 positive control 0.097 -0.273 -21.98 0.092 -0.26 -23.59 -32.2252 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A01 compound treatment 0.34 0.00263 0.21 0.336 0.00663 0.6 0.5747 0.9016 2065275 ICCB5_000001 O=C(N[C@@H]1[C@@H](COC(=O)c2ccccc2)Nc3cc4OCOc4cc13)OCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A02 compound treatment 0.328 -0.00937 -0.75 0.322 -0.00737 -0.67 -1.0072 -0.9982 2065276 ICCB5_000002 COCCOCOc1ccc2N([C@@H](Cc2c1)C(O)C=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A03 compound treatment 0.32 -0.0174 -1.4 0.321 -0.00837 -0.76 -1.5269 -0.9589 2065277 ICCB5_000003 OC[C@@H]1[C@@H](NC(=O)OCc2ccccc2)c3cc4OCOc4cc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A04 compound treatment 0.344 0.00662 0.53 0.346 0.0166 1.51 1.4443 0.9024 2065278 ICCB5_000004 COCCOCOc1ccc2[C@H](NC(=O)[C@H](C)NC(=O)OCc3ccccc3)[C@@H](COC(=O)c4ccccc4)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A05 compound treatment 0.335 -0.00237 -0.19 0.329 -3.75E-4 -0.03 -0.1593 -0.8201 2065279 ICCB5_000005 O=C(N[C@@H]1[C@@H](COC(=O)c2ccccc2)N(C(=O)OCC3c4ccccc4-c5ccccc35)c6cc7OCOc7cc16)OCc8ccccc8 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A06 compound treatment 0.319 -0.0184 -1.48 0.316 -0.0134 -1.21 -1.9048 -0.9952 2065280 ICCB5_000006 COCCOCOc1ccc2[C@H](NC(=O)OCC=C)[C@H](Oc2c1)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A07 compound treatment 0.35 0.0126 1.02 0.33 6.25E-4 0.06 0.759 0.7454 2065281 ICCB5_000007 ClC(Cl)(Cl)COC(=O)N1[C@H](COC(=O)c2ccccc2)[C@@H](NC(=O)OCc3ccccc3)c4cc5OCOc5cc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A08 compound treatment 0.345 0.00762 0.61 0.347 0.0176 1.6 1.5654 0.9135 2065282 ICCB5_000008 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1NC(=O)[C@H](Cc3ccccc3)NC(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A09 compound treatment 0.301 -0.0364 -2.93 0.299 -0.0304 -2.76 -4.0208 -0.9995 2065283 ICCB5_000009 O=C(N[C@@H]1[C@H]2C=CC(=O)N2c3cc4OCOc4cc13)OCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A10 compound treatment 0.331 -0.00637 -0.51 0.33 6.25E-4 0.06 -0.3229 -0.6252 2065284 ICCB5_000010 COCCOCOc1ccc2[C@H](N)[C@H](Oc2c1)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A11 compound treatment 0.346 0.00862 0.69 0.348 0.0186 1.69 1.6866 0.9228 2065285 ICCB5_000011 COCCOCOc1ccc2N[C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCc4ccccc4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A12 compound treatment 0.316 -0.0214 -1.72 0.311 -0.0184 -1.67 -2.3965 -0.9999 2065286 ICCB5_000012 COCCOCOc1ccc2[C@H](NC(=O)OCC=C)[C@H](Oc2c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A13 compound treatment 0.353 0.0156 1.26 0.348 0.0186 1.69 2.0851 0.9894 2065287 ICCB5_000013 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCc4ccccc4)c2c1)C(=O)OCC(Cl)(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A14 compound treatment 0.334 -0.00337 -0.27 0.333 0.00363 0.33 0.0405 0.0949 2065288 ICCB5_000014 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A15 compound treatment 0.391 0.0536 4.32 0.363 0.0336 3.05 5.2117 0.9856 2065289 ICCB5_000015 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCC=C)c2c1)C(=O)OCC(Cl)(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A16 compound treatment 0.333 -0.00437 -0.35 0.348 0.0186 1.69 0.9463 0.548 2065290 ICCB5_000016 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1NCc3ccc(Br)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A17 compound treatment 0.349 0.0116 0.94 0.343 0.0136 1.24 1.5365 0.9906 2065291 ICCB5_000017 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCc4ccccc4)c2c1)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A18 compound treatment 0.342 0.00463 0.37 0.343 0.0136 1.24 1.1379 0.881 2065292 ICCB5_000018 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A19 compound treatment 0.368 0.0306 2.47 0.356 0.0266 2.42 3.4527 0.9999 2065293 ICCB5_000019 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCc4ccccc4)c2c1)C(=O)OCC[Si](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A20 compound treatment 0.336 -0.00137 -0.11 0.333 0.00363 0.33 0.1544 0.4447 2065294 ICCB5_000020 COCCOCOc1ccc2[C@@H]([C@@H](CO)Oc2c1)N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A21 compound treatment 0.354 0.0166 1.34 0.351 0.0216 1.96 2.3346 0.9826 2065295 ICCB5_000021 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCC=C)c2c1)C(=O)OCC[Si](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A22 compound treatment 0.327 -0.0104 -0.84 0.331 0.00163 0.15 -0.4865 -0.5734 2065296 ICCB5_000022 COCCOCOc1ccc2[C@@H]([C@H](Oc2c1)[C@@H](O)CC=C)N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A23 mock treatment 0.331 -0.00637 -0.51 0.316 -0.0134 -1.21 -1.2215 -0.9267 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 A24 positive control 0.083 -0.254 -20.48 0.081 -0.248 -22.55 -30.4263 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B01 compound treatment 0.362 0.0246 1.98 0.363 0.0336 3.05 3.5604 0.9782 2065297 ICCB5_000023 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B02 compound treatment 0.412 0.0746 6.01 0.421 0.0916 8.32 10.1302 0.9873 2065298 ICCB5_000024 CCOC(=O)[C@@H]1OC(C)(C)N([C@H]1c2cc(OCOCCOC)ccc2[N+](=O)[O-])C(=O)OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B03 compound treatment 0.347 0.00962 0.78 0.338 0.00863 0.78 1.1017 1.0 2065299 ICCB5_000025 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B04 compound treatment 0.359 0.0216 1.74 0.346 0.0166 1.51 2.2984 0.9975 2065300 ICCB5_000026 CCOC(=O)C[C@@H]1Nc2cc3OCOc3cc2[C@H]4[C@H]1OC(C)(C)N4C(=O)OCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B05 compound treatment 0.358 0.0206 1.66 0.355 0.0256 2.33 2.8191 0.9864 2065301 ICCB5_000027 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B06 compound treatment 0.364 0.0266 2.14 0.362 0.0326 2.96 3.6101 0.9874 2065302 ICCB5_000028 CCOC(=O)[C@H]1Nc2ccc(OCOCCOC)cc2C[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B07 compound treatment 0.343 0.00563 0.45 0.338 0.00863 0.78 0.8739 0.9662 2065303 ICCB5_000029 CCCCCC/C=C\CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B08 compound treatment 0.347 0.00962 0.78 0.343 0.0136 1.24 1.4226 0.9747 2065304 ICCB5_000030 COCCOCOc1ccc2N([C@H](CO[Si](C)(C)C(C)(C)C)[C@H](Cc2c1)OC(=O)OCC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B09 compound treatment 0.334 -0.00337 -0.27 0.325 -0.00437 -0.4 -0.473 -0.9829 2065305 ICCB5_000031 CCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B10 compound treatment 0.28 -0.0574 -4.62 0.274 -0.0554 -5.03 -6.8212 -0.9991 2065306 ICCB5_000032 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](Cc2cc(O)ccc2N1C(=O)OCC=C)OC(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B11 compound treatment 0.356 0.0186 1.5 0.356 0.0266 2.42 2.7695 0.9737 2065307 ICCB5_000033 CCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B12 compound treatment 0.368 0.0306 2.47 0.363 0.0336 3.05 3.902 0.9944 2065308 ICCB5_000034 COCCOCOc1ccc2N([C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)Cc2c1)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B13 compound treatment 0.34 0.00263 0.21 0.328 -0.00137 -0.12 0.0612 0.2494 2065309 ICCB5_000035 CCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B14 compound treatment 0.366 0.0286 2.31 0.351 0.0216 1.96 3.0179 0.9968 2065310 ICCB5_000036 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2Cc3cc(O)ccc3N1C(=O)/C=C\CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B15 compound treatment 0.349 0.0116 0.94 0.334 0.00463 0.42 0.9588 0.9345 2065311 ICCB5_000037 CCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B16 compound treatment 0.366 0.0286 2.31 0.36 0.0306 2.78 3.5956 0.9957 2065312 ICCB5_000038 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2Cc3cc4OCOc4cc3N1C(=O)/C=C\CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B17 compound treatment 0.341 0.00363 0.29 0.327 -0.00237 -0.22 0.054 0.1487 2065313 ICCB5_000039 CCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B18 compound treatment 0.342 0.00463 0.37 0.34 0.0106 0.96 0.9453 0.9144 2065314 ICCB5_000040 OC[C@@H]1[C@@H]2Cc3cc4OCOc4cc3N1C(=O)/C=C\CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B19 compound treatment 0.349 0.0116 0.94 0.34 0.0106 0.96 1.3439 0.9999 2065315 ICCB5_000041 CCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B20 compound treatment 0.34 0.00263 0.21 0.339 0.00963 0.87 0.7673 0.8536 2065316 ICCB5_000042 CC(C)(C)C(=O)OC[C@@H]1[C@@H]2Cc3cc4OCOc4cc3N1C(=O)/C=C\CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B21 compound treatment 0.367 0.0296 2.39 0.361 0.0316 2.87 3.7167 0.9958 2065317 ICCB5_000043 CCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B22 compound treatment 0.352 0.0146 1.18 0.345 0.0156 1.42 1.8357 0.9957 2065318 ICCB5_000044 C[Si](C)(CBr)OC[C@@H]1[C@@H]2Cc3cc4OCOc4cc3N1C(=O)/C=C\CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B23 mock treatment 0.341 0.00363 0.29 0.333 0.00363 0.33 0.4391 0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 B24 positive control 0.084 -0.253 -20.4 0.082 -0.247 -22.45 -30.3052 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C01 compound treatment 0.359 0.0216 1.74 0.361 0.0316 2.87 3.2612 0.9713 2065319 ICCB5_000045 COCCOCOc1ccc2N([C@H](CO)[C@@H](NC(=O)OCC=C)c2c1)C(=O)OCC[Si](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C02 compound treatment 0.36 0.0226 1.82 0.366 0.0366 3.32 3.6391 0.9599 2065320 ICCB5_000046 COCCOCOc1ccc2[C@@H]([C@H](Oc2c1)[C@H](O)CC=C)N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C03 compound treatment 0.38 0.0426 3.43 0.377 0.0476 4.32 5.4839 0.9935 2065321 ICCB5_000047 CCOC(=O)/C=C/[C@@H]1[C@@H](NC(=O)OCC=C)c2cc(OCOCCOC)ccc2N1C(=O)OCC[Si](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C04 compound treatment 0.36 0.0226 1.82 0.355 0.0256 2.33 2.933 0.9927 2065322 ICCB5_000048 COCCOCOc1ccc2[C@H]3[C@H](Oc2c1)[C@@H](CC=CC(=O)N3Cc4ccc(Br)cc4)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C05 compound treatment 0.357 0.0196 1.58 0.347 0.0176 1.6 2.2487 1.0 2065323 ICCB5_000049 CCOC(=O)/C=C/[C@H]1Nc2ccc(OCOCCOC)cc2[C@@H]1NC(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C06 compound treatment 0.357 0.0196 1.58 0.351 0.0216 1.96 2.5055 0.9942 2065324 ICCB5_000050 COCCOCOc1ccc2[C@H]3[C@H](Oc2c1)[C@H](CC=CC(=O)N3Cc4ccc(Br)cc4)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C07 compound treatment 0.357 0.0196 1.58 0.359 0.0296 2.69 3.0189 0.9679 2065325 ICCB5_000051 CCOC(=O)C[C@@H]1N[C@@H](C)C(=O)N2[C@H]1[C@@H](NC(=O)OCC=C)c3cc(OCOCCOC)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C08 compound treatment 0.361 0.0236 1.9 0.355 0.0256 2.33 2.99 0.995 2065326 ICCB5_000052 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2C[C@@H]1O[Si](CC)(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C09 compound treatment 0.355 0.0176 1.42 0.354 0.0246 2.24 2.5841 0.976 2065327 ICCB5_000053 CCOC(=O)/C=C/[C@@H]1[C@@H](NC(=O)OCC=C)c2cc(OCOCCOC)ccc2N1C(=O)OCC3c4ccccc4-c5ccccc35 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C10 compound treatment 0.332 -0.00537 -0.43 0.324 -0.00537 -0.49 -0.6511 -0.9982 2065328 ICCB5_000054 COCCOCOc1ccc2C[C@H](O)[C@@H](CO)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C11 compound treatment 0.354 0.0166 1.34 0.33 6.25E-4 0.06 0.9868 0.7364 2065329 ICCB5_000055 CCOC(=O)/C=C/[C@@H]1[C@@H](NC(=O)OCC=C)c2cc(O)ccc2N1C(=O)OCC3c4ccccc4-c5ccccc35 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C12 compound treatment 0.395 0.0576 4.64 0.38 0.0506 4.6 6.5306 1.0 2065330 ICCB5_000056 COCCOCOc1ccc2C[C@H](OC(=O)[C@H](Cc3ccccc3)NS(=O)(=O)c4ccccc4[N+](=O)[O-])[C@@H](CO[Si](C)(C)C(C)(C)C)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C13 compound treatment 0.357 0.0196 1.58 0.354 0.0246 2.24 2.698 0.9856 2065331 ICCB5_000057 COCCOCOc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)CCC=C)c2c1)C(=O)CCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C14 compound treatment 0.335 -0.00237 -0.19 0.326 -0.00337 -0.31 -0.3519 -0.9743 2065332 ICCB5_000058 CCOC(=O)[C@H](Cc1ccccc1)NC[C@H]2Oc3cc(OCOCCOC)ccc3C[C@@H]2O[Si](CC)(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C15 compound treatment 0.335 -0.00237 -0.19 0.326 -0.00337 -0.31 -0.3519 -0.9743 2065333 ICCB5_000059 Oc1ccc2N([C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)CCC=C)c2c1)C(=O)CCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C16 compound treatment 0.359 0.0216 1.74 0.354 0.0246 2.24 2.8119 0.9924 2065334 ICCB5_000060 CCOC(=O)[C@H](Cc1ccccc1)N(C[C@H]2Oc3cc(OCOCCOC)ccc3C[C@@H]2O[Si](CC)(CC)CC)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C17 compound treatment 0.363 0.0256 2.06 0.355 0.0256 2.33 3.1039 0.9982 2065335 ICCB5_000061 COCCOCOc1ccc2N3[C@H](COC(=O)c4ccccc4)[C@@H](NC(=O)CC/C=C/CCC3=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C18 compound treatment 0.332 -0.00537 -0.43 0.321 -0.00837 -0.76 -0.8436 -0.9644 2065336 ICCB5_000062 CCOC(=O)[C@H]1Oc2cc(O)ccc2C[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C19 compound treatment 0.323 -0.0144 -1.16 0.313 -0.0164 -1.49 -1.8696 -0.9924 2065337 ICCB5_000063 CCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C20 compound treatment 0.315 -0.0224 -1.8 0.315 -0.0144 -1.3 -2.1967 -0.9874 2065338 ICCB5_000064 CCOC(=O)[C@H]1Oc2cc(OCc3ccccc3)ccc2C[C@@H]1O[Si](CC)(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C21 compound treatment 0.302 -0.0354 -2.85 0.302 -0.0274 -2.48 -3.7713 -0.9977 2065339 ICCB5_000065 CCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C22 compound treatment 0.306 -0.0314 -2.53 0.304 -0.0254 -2.3 -3.4152 -0.9989 2065340 ICCB5_000066 O=Cc1ccc(OCc2ccccc2)cc1OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C23 mock treatment 0.329 -0.00837 -0.67 0.32 -0.00937 -0.85 -1.0786 -0.9934 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 C24 positive control 0.088 -0.249 -20.08 0.082 -0.247 -22.45 -30.0774 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D01 compound treatment 0.366 0.0286 2.31 0.358 0.0286 2.6 3.4672 0.9982 2065341 ICCB5_000067 CCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D02 compound treatment 0.334 -0.00337 -0.27 0.329 -3.75E-4 -0.03 -0.2162 -0.7895 2065342 ICCB5_000068 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2Cc3cc4OCOc4cc3N1C(=O)OC/C=C/CCC(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D03 compound treatment 0.357 0.0196 1.58 0.346 0.0166 1.51 2.1845 0.9997 2065343 ICCB5_000069 CCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D04 compound treatment 0.32 -0.0174 -1.4 0.316 -0.0134 -1.21 -1.8478 -0.9975 2065344 ICCB5_000070 CCOC(=O)[C@@H](O)[C@@H](NC(=O)OCc1ccccc1)c2cc(OCc3ccccc3)ccc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D05 compound treatment 0.334 -0.00337 -0.27 0.329 -3.75E-4 -0.03 -0.2162 -0.7895 2065345 ICCB5_000071 CCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D06 compound treatment 0.323 -0.0144 -1.16 0.319 -0.0104 -0.94 -1.4844 -0.9948 2065346 ICCB5_000072 CCOC(=O)[C@@H]1OC(C)(C)N([C@H]1c2cc(OCc3ccccc3)ccc2[N+](=O)[O-])C(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D07 compound treatment 0.366 0.0286 2.31 0.362 0.0326 2.96 3.724 0.9923 2065347 ICCB5_000073 CCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D08 compound treatment 0.374 0.0366 2.95 0.358 0.0286 2.6 3.9228 0.998 2065348 ICCB5_000074 CCOC(=O)C[C@@H]1Nc2cc3OCOc3cc2[C@@H]4OC(C)(C)O[C@H]41 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D09 compound treatment 0.367 0.0296 2.39 0.355 0.0256 2.33 3.3316 0.9999 2065349 ICCB5_000075 CCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D10 compound treatment 0.363 0.0256 2.06 0.367 0.0376 3.42 3.8741 0.9709 2065350 ICCB5_000076 CCOC(=O)C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc4OCOc4cc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D11 compound treatment 0.368 0.0306 2.47 0.361 0.0316 2.87 3.7737 0.9971 2065351 ICCB5_000077 CCCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D12 compound treatment 0.366 0.0286 2.31 0.359 0.0296 2.69 3.5314 0.9971 2065352 ICCB5_000078 CCOC(=O)C[C@H]1[C@H](O)[C@@H](O)c2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D13 compound treatment 0.372 0.0346 2.79 0.362 0.0326 2.96 4.0656 0.9995 2065353 ICCB5_000079 CCCCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D14 compound treatment 0.363 0.0256 2.06 0.35 0.0206 1.87 2.7829 0.9988 2065354 ICCB5_000080 CCOC(=O)/C=C\[C@@H]1OC(C)(C)O[C@H]1c2cc3OCOc3cc2NCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D15 compound treatment 0.362 0.0246 1.98 0.355 0.0256 2.33 3.0469 0.9968 2065355 ICCB5_000081 CCCCCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D16 compound treatment 0.341 0.00363 0.29 0.325 -0.00437 -0.4 -0.0744 -0.151 2065356 ICCB5_000082 CC(C)(C)[Si](C)(C)O[C@H]([C@H]1OC(=O)C=C1)c2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D17 compound treatment 0.37 0.0326 2.63 0.356 0.0266 2.42 3.5666 0.9991 2065357 ICCB5_000083 CCCCCCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D18 compound treatment 0.349 0.0116 0.94 0.349 0.0196 1.78 1.9216 0.9549 2065358 ICCB5_000084 CCOC(=O)C[C@@H]1C[C@H]2[C@H](O)[C@@H](O1)c3cc4OCOc4cc3N2C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D19 compound treatment 0.345 0.00762 0.61 0.338 0.00863 0.78 0.9878 0.9928 2065359 ICCB5_000085 CCCCCC/C=C\CCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D20 compound treatment 0.346 0.00862 0.69 0.336 0.00663 0.6 0.9163 0.9974 2065360 ICCB5_000086 COC(=O)C[C@@H]1C[C@H]2[C@H](O)[C@@H](O1)c3cc4OCOc4cc3N2C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D21 compound treatment 0.356 0.0186 1.5 0.351 0.0216 1.96 2.4485 0.9912 2065361 ICCB5_000087 CCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D22 compound treatment 0.348 0.0106 0.86 0.339 0.00963 0.87 1.2228 0.9999 2065362 ICCB5_000088 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N([C@H]2CCO)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D23 mock treatment 0.338 6.25E-4 0.05 0.333 0.00363 0.33 0.2683 0.8059 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 D24 positive control 0.088 -0.249 -20.08 0.084 -0.245 -22.27 -29.949 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E01 compound treatment 0.325 -0.0124 -1.0 0.318 -0.0114 -1.03 -1.4347 -0.9998 2065363 ICCB5_000089 CCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E02 compound treatment 0.33 -0.00737 -0.59 0.326 -0.00337 -0.31 -0.6366 -0.9526 2065364 ICCB5_000090 O=CCc1ccc(OCc2ccccc2)cc1OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E03 compound treatment 0.317 -0.0204 -1.64 0.301 -0.0284 -2.58 -2.9814 -0.9763 2065365 ICCB5_000091 CCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E04 compound treatment 0.317 -0.0204 -1.64 0.314 -0.0154 -1.4 -2.147 -0.9968 2065366 ICCB5_000092 CCOC(=O)/C=C/Cc1ccc(OCc2ccccc2)cc1OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E05 compound treatment 0.324 -0.0134 -1.08 0.319 -0.0104 -0.94 -1.4275 -0.9978 2065367 ICCB5_000093 CCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E06 compound treatment 0.365 0.0276 2.22 0.344 0.0146 1.33 2.5117 0.9696 2065368 ICCB5_000094 CCOC(=O)[C@H](O)[C@@H](O)Cc1ccc(OCc2ccccc2)cc1OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E07 compound treatment 0.338 6.25E-4 0.05 0.331 0.00163 0.15 0.1399 0.8976 2065369 ICCB5_000095 CCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E08 compound treatment 0.354 0.0166 1.34 0.335 0.00563 0.51 1.3077 0.9127 2065370 ICCB5_000096 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)Cc2ccc(OCc3ccccc3)cc2OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E09 compound treatment 0.354 0.0166 1.34 0.364 0.0346 3.14 3.169 0.9277 2065371 ICCB5_000097 CCOC(=O)[C@H](O)[C@@H](NC(=O)OCc1ccccc1)c2cc(OCOCCOC)ccc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E10 compound treatment 0.354 0.0166 1.34 0.335 0.00563 0.51 1.3077 0.9127 2065372 ICCB5_000098 COCCOCOc1ccc(C=C)c(OCc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E11 compound treatment 0.358 0.0206 1.66 0.349 0.0196 1.78 2.434 0.9994 2065373 ICCB5_000099 COCCOCOc1ccc([N+](=O)[O-])c(c1)[C@H](NC(=O)OCc2ccccc2)[C@@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E12 compound treatment 0.326 -0.0114 -0.92 0.311 -0.0184 -1.67 -1.8271 -0.9602 2065374 ICCB5_000100 CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E13 compound treatment 0.365 0.0276 2.22 0.356 0.0266 2.42 3.2819 0.9991 2065375 ICCB5_000101 COCCOCOc1ccc([N+](=O)[O-])c(c1)[C@H](NC(=O)OCc2ccccc2)[C@@H](O)COC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E14 compound treatment 0.328 -0.00937 -0.75 0.318 -0.0114 -1.03 -1.2639 -0.9882 2065376 ICCB5_000102 COCCOCOc1ccc(CC=O)c(OCc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E15 compound treatment 0.378 0.0406 3.27 0.367 0.0376 3.42 4.7282 0.9998 2065377 ICCB5_000103 COCCOCOc1ccc([N+](=O)[O-])c(c1)[C@H](NC(=O)OCc2ccccc2)[C@H](COC(=O)c3ccccc3)OS(=O)(=O)c4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E16 compound treatment 0.365 0.0276 2.22 0.354 0.0246 2.24 3.1535 1.0 2065378 ICCB5_000104 CCOC(=O)/C=C/Cc1ccc(OCOCCOC)cc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E17 compound treatment 0.362 0.0246 1.98 0.351 0.0216 1.96 2.7902 1.0 2065285 ICCB5_000105 COCCOCOc1ccc2N[C@H](COC(=O)c3ccccc3)[C@@H](NC(=O)OCc4ccccc4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E18 compound treatment 0.36 0.0226 1.82 0.359 0.0296 2.69 3.1898 0.982 2065379 ICCB5_000106 CCOC(=O)[C@H](O)[C@@H](O)Cc1ccc(OCOCCOC)cc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E19 compound treatment 0.346 0.00862 0.69 0.341 0.0116 1.06 1.2373 0.9794 2065380 ICCB5_000107 CCOC(=O)/C=C/c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E20 compound treatment 0.238 -0.0994 -8.0 0.247 -0.0824 -7.48 -10.9457 -0.9994 2065381 ICCB5_000108 CCCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E21 compound treatment 0.351 0.0136 1.1 0.349 0.0196 1.78 2.0355 0.9729 2065382 ICCB5_000109 CCOC(=O)[C@H](O)[C@@H](O)c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E22 compound treatment 0.334 -0.00337 -0.27 0.329 -3.75E-4 -0.03 -0.2162 -0.7895 2065383 ICCB5_000110 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2C[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E23 mock treatment 0.334 -0.00337 -0.27 0.329 -3.75E-4 -0.03 -0.2162 -0.7895 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 E24 positive control 0.09 -0.247 -19.92 0.086 -0.243 -22.09 -29.7068 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F01 compound treatment 0.361 0.0236 1.9 0.355 0.0256 2.33 2.99 0.995 2065384 ICCB5_000111 CCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F02 compound treatment 0.345 0.00762 0.61 0.338 0.00863 0.78 0.9878 0.9928 2065385 ICCB5_000112 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N[C@H]2CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F03 compound treatment 0.364 0.0266 2.14 0.358 0.0286 2.6 3.3533 0.9954 2065386 ICCB5_000113 CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F04 compound treatment 0.319 -0.0184 -1.48 0.318 -0.0114 -1.03 -1.7764 -0.9845 2065387 ICCB5_000114 CCOC(=O)C[C@@H]1Nc2ccc(O)cc2[C@@H]3OC(C)(C)O[C@H]31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F05 compound treatment 0.356 0.0186 1.5 0.344 0.0146 1.33 1.9992 0.9981 2065388 ICCB5_000115 CCCCCCCC/C=C\CCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F06 compound treatment 0.342 0.00463 0.37 0.338 0.00863 0.78 0.8169 0.9423 2065389 ICCB5_000116 CCOC(=O)C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc(O)ccc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F07 compound treatment 0.29 -0.0474 -3.81 0.306 -0.0234 -2.12 -4.1979 -0.9617 2065390 ICCB5_000117 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F08 compound treatment 0.375 0.0376 3.03 0.352 0.0226 2.05 3.5946 0.9821 2065391 ICCB5_000118 CCOC(=O)C[C@@H]1Nc2ccc(OC(=O)OCC=C)cc2[C@@H]3OC(C)(C)O[C@H]31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F09 compound treatment 0.361 0.0236 1.9 0.358 0.0286 2.6 3.1825 0.9883 2065392 ICCB5_000119 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F10 compound treatment 0.387 0.0496 4.0 0.373 0.0436 3.96 5.6258 1.0 2065393 ICCB5_000120 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N([C@H]2CCO)C(=O)OCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F11 compound treatment 0.316 -0.0214 -1.72 0.314 -0.0154 -1.4 -2.204 -0.9946 2065394 ICCB5_000121 CCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F12 compound treatment 0.339 0.00163 0.13 0.326 -0.00337 -0.31 -0.1241 -0.3725 2065395 ICCB5_000122 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N([C@H]2CCOC(=O)OCc5ccccc5)C(=O)OCc6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F13 compound treatment 0.369 0.0316 2.55 0.353 0.0236 2.14 3.3171 0.9963 2065396 ICCB5_000123 CCCCCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F14 compound treatment 0.311 -0.0264 -2.12 0.309 -0.0204 -1.85 -2.8096 -0.9976 2065397 ICCB5_000124 CC1(C)O[C@@H]2[C@@H](O1)c3cc(O)ccc3N[C@H]2CCOC(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F15 compound treatment 0.335 -0.00237 -0.19 0.331 0.00163 0.15 -0.0309 -0.1281 2065398 ICCB5_000125 CCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F16 compound treatment 0.343 0.00563 0.45 0.334 0.00463 0.42 0.6171 0.9993 2065399 ICCB5_000126 CC1(C)O[C@@H]2[C@@H](O1)c3cc(O)ccc3N([C@H]2CCOC(=O)OCc4ccccc4)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F17 compound treatment 0.341 0.00363 0.29 0.335 0.00563 0.51 0.5675 0.9648 2065400 ICCB5_000127 CCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F18 compound treatment 0.341 0.00363 0.29 0.34 0.0106 0.96 0.8884 0.8816 2065401 ICCB5_000128 CCOC(=O)/C=C/C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc(O)ccc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F19 compound treatment 0.356 0.0186 1.5 0.348 0.0186 1.69 2.256 0.9982 2065402 ICCB5_000129 CCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F20 compound treatment 0.34 0.00263 0.21 0.334 0.00463 0.42 0.4463 0.9496 2065403 ICCB5_000130 CCOC(=O)C[C@@H]1C[C@H]2[C@H](O)[C@@H](O1)c3cc(O)ccc3N2C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F21 compound treatment 0.319 -0.0184 -1.48 0.312 -0.0174 -1.58 -2.1615 -0.9995 2065404 ICCB5_000131 CCCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F22 compound treatment 0.341 0.00363 0.29 0.336 0.00663 0.6 0.6316 0.9449 2065405 ICCB5_000132 CCOC(=O)/C=C/C[C@H]1[C@H](O)[C@@H](O)c2cc(O)ccc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F23 mock treatment 0.342 0.00463 0.37 0.33 6.25E-4 0.06 0.3035 0.8055 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 F24 positive control 0.089 -0.248 -20.0 0.086 -0.243 -22.09 -29.7637 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G01 compound treatment 0.359 0.0216 1.74 0.34 0.0106 0.96 1.9133 0.9612 2065406 ICCB5_000133 CCOC(=O)[C@@H](O)[C@H](O)c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G02 compound treatment 0.338 6.25E-4 0.05 0.334 0.00463 0.42 0.3324 0.7862 2065407 ICCB5_000134 CN1C(=O)C2C(C3N(Cc4ccccc4I)C2C=CC3=O)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G03 compound treatment 0.325 -0.0124 -1.0 0.322 -0.00737 -0.67 -1.178 -0.9813 2065408 ICCB5_000135 CCOC(=O)[C@H](O)[C@@H](O)c1cc2OCOc2cc1NC(=O)OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G04 compound treatment 0.332 -0.00537 -0.43 0.324 -0.00537 -0.49 -0.6511 -0.9982 2065409 ICCB5_000136 COc1cccc(C=C)c1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G05 compound treatment 0.313 -0.0244 -1.96 0.302 -0.0274 -2.48 -3.145 -0.9932 2065410 ICCB5_000137 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)c2cc3OCOc3cc2NC(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G06 compound treatment 0.337 -3.75E-4 -0.03 0.323 -0.00637 -0.58 -0.4305 -0.743 2065411 ICCB5_000138 COc1cccc(CCO)c1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G07 compound treatment 0.345 0.00762 0.61 0.328 -0.00137 -0.12 0.3459 0.5521 2065412 ICCB5_000139 CCOC(=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G08 compound treatment 0.322 -0.0154 -1.24 0.316 -0.0134 -1.21 -1.7339 -1.0 2065413 ICCB5_000140 COc1cccc(CC=O)c1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G09 compound treatment 0.348 0.0106 0.86 0.33 6.25E-4 0.06 0.6451 0.7523 2065414 ICCB5_000141 CCOC(=O)[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G10 compound treatment 0.332 -0.00537 -0.43 0.322 -0.00737 -0.67 -0.7794 -0.9777 2065415 ICCB5_000142 CCOC(=O)/C=C/Cc1cccc(OC)c1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G11 compound treatment 0.336 -0.00137 -0.11 0.346 0.0166 1.51 0.9888 0.6535 2065416 ICCB5_000143 CC(C)(C)[Si](C)(C)OC[C@H](O)[C@@H](O)c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G12 compound treatment 0.347 0.00962 0.78 0.337 0.00763 0.69 1.0375 0.9984 2065417 ICCB5_000144 CCOC(=O)[C@H](O)[C@@H](O)Cc1cccc(OC)c1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G13 compound treatment 0.36 0.0226 1.82 0.35 0.0206 1.87 2.6121 0.9999 2065418 ICCB5_000145 CC(C)(C)[Si](C)(C)OC[C@@H]1OC(C)(C)O[C@H]1c2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G14 compound treatment 0.335 -0.00237 -0.19 0.328 -0.00137 -0.12 -0.2235 -0.9786 2065419 ICCB5_000146 CC[Si](CC)(CC)O[C@H]1Cc2ccc(OCc3ccccc3)cc2O[C@@H]1CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G15 compound treatment 0.358 0.0206 1.66 0.349 0.0196 1.78 2.434 0.9994 2065420 ICCB5_000147 CCOC(=O)[C@@H]1OC(C)(C)O[C@H]1c2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G16 compound treatment 0.332 -0.00537 -0.43 0.321 -0.00837 -0.76 -0.8436 -0.9644 2065421 ICCB5_000148 CC[Si](CC)(CC)O[C@H]1Cc2ccc(OCc3ccccc3)cc2O[C@@H]1C=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G17 compound treatment 0.356 0.0186 1.5 0.352 0.0226 2.05 2.5127 0.9881 2065422 ICCB5_000149 OCCCc1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G18 compound treatment 0.319 -0.0184 -1.48 0.309 -0.0204 -1.85 -2.3541 -0.9939 2065423 ICCB5_000150 CC[Si](CC)(CC)O[C@H]1Cc2ccc(OCc3ccccc3)cc2O[C@@H]1C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G19 compound treatment 0.347 0.00962 0.78 0.357 0.0276 2.51 2.3212 0.8844 2065424 ICCB5_000151 OC/C=C/c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G20 compound treatment 0.324 -0.0134 -1.08 0.316 -0.0134 -1.21 -1.6201 -0.9982 2065425 ICCB5_000152 C(Oc1ccc2C[C@@H]3OCC=C[C@H]3Oc2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G21 compound treatment 0.346 0.00862 0.69 0.34 0.0106 0.96 1.1731 0.987 2065426 ICCB5_000153 [O-][N+](=O)c1cc2OCOc2cc1CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G22 compound treatment 0.325 -0.0124 -1.0 0.324 -0.00537 -0.49 -1.0496 -0.946 2065427 ICCB5_000154 C(Oc1ccc2C[C@@H]3OCCCC=C[C@H]3Oc2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G23 mock treatment 0.336 -0.00137 -0.11 0.331 0.00163 0.15 0.026 0.141 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 G24 positive control 0.09 -0.247 -19.92 0.087 -0.242 -22.0 -29.6426 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H01 compound treatment 0.356 0.0186 1.5 0.347 0.0176 1.6 2.1918 0.9995 2065428 ICCB5_000155 CCCCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H02 compound treatment 0.357 0.0196 1.58 0.368 0.0386 3.51 3.5966 0.9352 2065429 ICCB5_000156 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N([C@H]2CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H03 compound treatment 0.369 0.0316 2.55 0.361 0.0316 2.87 3.8306 0.9982 2065430 ICCB5_000157 CCCCCCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H04 compound treatment 0.341 0.00363 0.29 0.337 0.00763 0.69 0.6958 0.9263 2065431 ICCB5_000158 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N([C@H]2CC=C)C(=O)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H05 compound treatment 0.363 0.0256 2.06 0.356 0.0266 2.42 3.168 0.9969 2065432 ICCB5_000159 CCCCCCCCCCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H06 compound treatment 0.394 0.0566 4.56 0.374 0.0446 4.05 6.0885 0.9983 2065433 ICCB5_000160 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N([C@H]2CCOC(=O)OCC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H07 compound treatment 0.328 -0.00937 -0.75 0.366 0.0366 3.32 1.817 0.533 2065434 ICCB5_000161 CCCCCCCC/C=C\CCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H08 compound treatment 0.351 0.0136 1.1 0.338 0.00863 0.78 1.3294 0.9863 2065435 ICCB5_000162 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N([C@H]2CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H09 compound treatment 0.373 0.0356 2.87 0.357 0.0276 2.51 3.8016 0.9978 2065436 ICCB5_000163 CCCCC/C=C\C/C=C\CCCCCCCC(=O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H10 compound treatment 0.365 0.0276 2.22 0.365 0.0356 3.23 3.8596 0.9833 2065437 ICCB5_000164 CC1(C)O[C@@H]2[C@@H](O1)c3cc(OCc4ccccc4)ccc3N([C@H]2CCO)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H11 compound treatment 0.319 -0.0184 -1.48 0.31 -0.0194 -1.76 -2.2899 -0.9963 2065438 ICCB5_000165 CCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H12 compound treatment 0.34 0.00263 0.21 0.332 0.00263 0.24 0.318 0.9982 2065439 ICCB5_000166 CC1(C)O[C@@H]2[C@@H](O1)c3cc(O)ccc3N([C@H]2CC=O)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H13 compound treatment 0.347 0.00962 0.78 0.334 0.00463 0.42 0.8449 0.9585 2065440 ICCB5_000167 CCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H14 compound treatment 0.338 6.25E-4 0.05 0.327 -0.00237 -0.22 -0.1169 -0.5278 2065441 ICCB5_000168 CC1(C)O[C@@H]2[C@@H](O1)c3cc(O)ccc3N([C@H]2CCO)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H15 compound treatment 0.339 0.00163 0.13 0.325 -0.00437 -0.4 -0.1883 -0.4503 2065442 ICCB5_000169 CCCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H16 compound treatment 0.339 0.00163 0.13 0.342 0.0126 1.15 0.9029 0.7828 2065443 ICCB5_000170 COCCOCOc1ccc2N([C@@H](CC(=O)O)[C@@H]3OC(C)(C)O[C@H]3c2c1)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H17 compound treatment 0.35 0.0126 1.02 0.337 0.00763 0.69 1.2083 0.9824 2065444 ICCB5_000171 CCCCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H18 compound treatment 0.388 0.0506 4.08 0.383 0.0536 4.87 6.3246 0.9961 2065445 ICCB5_000172 CCOC(=O)C[C@@H]1C[C@H]2[C@H](O)[C@@H](O1)c3cc(OCc4ccccc4)ccc3N2C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H19 compound treatment 0.349 0.0116 0.94 0.345 0.0156 1.42 1.6648 0.9797 2065446 ICCB5_000173 CCCCCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H20 compound treatment 0.375 0.0376 3.03 0.376 0.0466 4.23 5.135 0.9866 2065447 ICCB5_000174 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N([C@H]2C[C@@H](O)CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H21 compound treatment 0.36 0.0226 1.82 0.346 0.0166 1.51 2.3554 0.9956 2065448 ICCB5_000175 CCCCCCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H22 compound treatment 0.37 0.0326 2.63 0.359 0.0296 2.69 3.7592 0.9999 2065449 ICCB5_000176 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N[C@H]2C[C@@H](O)CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H23 mock treatment 0.338 6.25E-4 0.05 0.336 0.00663 0.6 0.4608 0.7636 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 H24 positive control 0.092 -0.245 -19.76 0.088 -0.241 -21.91 -29.4645 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I01 compound treatment 0.361 0.0236 1.9 0.35 0.0206 1.87 2.669 1.0 2065450 ICCB5_000177 OC[C@H](O)Cc1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I02 compound treatment 0.33 -0.00737 -0.59 0.328 -0.00137 -0.12 -0.5082 -0.8374 2065451 ICCB5_000178 Oc1ccc2C[C@H](OC(=O)c3ccccc3)[C@H](Oc2c1)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I03 compound treatment 0.351 0.0136 1.1 0.342 0.0126 1.15 1.5862 0.9998 2065452 ICCB5_000179 Nc1cc2OCOc2cc1C[C@@H](O)COC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I04 compound treatment 0.372 0.0346 2.79 0.346 0.0166 1.51 3.0387 0.9584 2065453 ICCB5_000180 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I05 compound treatment 0.337 -3.75E-4 -0.03 0.335 0.00563 0.51 0.3397 0.6641 2065454 ICCB5_000181 Cc1ccc(cc1)S(=O)(=O)O[C@@H](CO[Si](C)(C)C(C)(C)C)Cc2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I06 compound treatment 0.363 0.0256 2.06 0.359 0.0296 2.69 3.3606 0.9914 2065455 ICCB5_000182 CCOC(=O)[C@H]1Oc2cc(OCOCCOC)ccc2[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I07 compound treatment 0.35 0.0126 1.02 0.332 0.00263 0.24 0.8874 0.8498 2065456 ICCB5_000183 CC(C)(C)[Si](C)(C)OC[C@@H]1Cc2cc3OCOc3cc2N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I08 compound treatment 0.368 0.0306 2.47 0.366 0.0366 3.32 4.0946 0.9892 2065457 ICCB5_000184 COCCOCOc1ccc2[C@H](OCC=C)[C@@H](CO)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I09 compound treatment 0.353 0.0156 1.26 0.333 0.00363 0.33 1.1224 0.863 2065458 ICCB5_000185 O=C(OC[C@@H]1Cc2cc3OCOc3cc2N1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I10 compound treatment 0.369 0.0316 2.55 0.369 0.0396 3.6 4.3441 0.9857 2065459 ICCB5_000186 COCCOCOc1ccc2[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I11 compound treatment 0.328 -0.00937 -0.75 0.331 0.00163 0.15 -0.4295 -0.5584 2065460 ICCB5_000187 OC[C@@H]1Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I12 compound treatment 0.374 0.0366 2.95 0.355 0.0256 2.33 3.7302 0.9931 2065461 ICCB5_000188 CCOC(=O)[C@H](O)[C@@H](O)c1ccc(OCOCCOC)cc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I13 compound treatment 0.337 -3.75E-4 -0.03 0.326 -0.00337 -0.31 -0.238 -0.7731 2065462 ICCB5_000189 C=CCOC(=O)N1[C@@H](Cc2cc3OCOc3cc12)C=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I14 compound treatment 0.363 0.0256 2.06 0.353 0.0236 2.14 2.9755 0.9998 2065463 ICCB5_000190 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)c2ccc(OCOCCOC)cc2OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I15 compound treatment 0.323 -0.0144 -1.16 0.337 0.00763 0.69 -0.3291 -0.244 2065464 ICCB5_000191 O[C@@H](CC=C)[C@@H]1Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I16 compound treatment 0.334 -0.00337 -0.27 0.34 0.0106 0.96 0.4898 0.4888 2065465 ICCB5_000192 COCCOCOc1ccc2[C@H](O)[C@H](Oc2c1)C(CC=C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I17 compound treatment 0.326 -0.0114 -0.92 0.308 -0.0214 -1.94 -2.0197 -0.9413 2065466 ICCB5_000193 CC(C)(C)[Si](C)(C)O[C@@H](CC=C)[C@@H]1Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I18 compound treatment 0.381 0.0436 3.51 0.363 0.0336 3.05 4.6423 0.9975 2065467 ICCB5_000194 COCCOCOc1ccc2[C@H](NC(=O)OCC=C)[C@@H](COC(=O)c3ccccc3)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I19 compound treatment 0.327 -0.0104 -0.84 0.326 -0.00337 -0.31 -0.8074 -0.9073 2065468 ICCB5_000195 CC(C)(C)[Si](C)(C)O[C@H]1CC=CC(=O)N2[C@H]1Cc3cc4OCOc4cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I20 compound treatment 0.337 -3.75E-4 -0.03 0.329 -3.75E-4 -0.03 -0.0454 -0.9982 2065469 ICCB5_000196 CCOC(=O)[C@H]1Oc2cc(O)ccc2[C@@H]1NC(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I21 compound treatment 0.423 0.0856 6.9 0.409 0.0796 7.23 9.9863 0.9997 2065470 ICCB5_000197 CO/C=C/c1cc(O)ccc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I22 compound treatment 0.339 0.00163 0.13 0.338 0.00863 0.78 0.6461 0.814 2065471 ICCB5_000198 COCCOCOc1ccc(C=O)c(OCOCCOC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I23 mock treatment 0.343 0.00563 0.45 0.333 0.00363 0.33 0.553 0.9877 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 I24 positive control 0.093 -0.244 -19.68 0.088 -0.241 -21.91 -29.4076 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J01 compound treatment 0.351 0.0136 1.1 0.337 0.00763 0.69 1.2652 0.9753 2065472 ICCB5_000199 CCCCCCCCCCCCCC(=O)CC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J02 compound treatment 0.343 0.00563 0.45 0.334 0.00463 0.42 0.6171 0.9993 2065473 ICCB5_000200 CC1(C)O[C@@H]2[C@@H](O1)c3cc(O)ccc3N([C@H]2CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J03 compound treatment 0.337 -3.75E-4 -0.03 0.329 -3.75E-4 -0.03 -0.0454 -0.9982 2065474 ICCB5_000201 CC(O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J04 compound treatment 0.329 -0.00837 -0.67 0.327 -0.00237 -0.22 -0.6293 -0.8888 2065475 ICCB5_000202 CC1(C)O[C@@H]2[C@@H](O1)c3cc4OCOc4cc3N5[C@H]2C[C@H](CC5=O)Sc6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J05 compound treatment 0.348 0.0106 0.86 0.332 0.00263 0.24 0.7735 0.8709 2065476 ICCB5_000203 CCCCCCCC(O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J06 compound treatment 0.343 0.00563 0.45 0.343 0.0136 1.24 1.1948 0.9072 2065477 ICCB5_000204 CC(=O)O[C@@H]1CC=CC(=O)N2[C@@H](C1)[C@@H]3OC(C)(C)O[C@H]3c4cc5OCOc5cc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J07 compound treatment 0.364 0.0266 2.14 0.355 0.0256 2.33 3.1608 0.9992 2065478 ICCB5_000205 CCCCCCCCCC(O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J08 compound treatment 0.346 0.00862 0.69 0.331 0.00163 0.15 0.5954 0.8386 2065479 ICCB5_000206 CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O)c2cc(OC3CCCCO3)ccc2NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J09 compound treatment 0.367 0.0296 2.39 0.352 0.0226 2.05 3.1391 0.9972 2065480 ICCB5_000207 CCCCCCCCCCCC(O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J10 compound treatment 0.314 -0.0234 -1.88 0.32 -0.00937 -0.85 -1.9327 -0.9356 2065481 ICCB5_000208 CC(=O)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(=O)Nc2ccc(O)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J11 compound treatment 0.357 0.0196 1.58 0.367 0.0376 3.42 3.5324 0.9387 2065482 ICCB5_000209 CCCCCCCCCCCCCC(O)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J12 compound treatment 0.372 0.0346 2.79 0.36 0.0306 2.78 3.9372 1.0 2065483 ICCB5_000210 O[C@@H]1[C@@H](O)c2cc(OCc3ccccc3)ccc2N(C(=O)OCC=C)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J13 compound treatment 0.309 -0.0284 -2.28 0.304 -0.0254 -2.3 -3.2444 -1.0 2065484 ICCB5_000211 CCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J14 compound treatment 0.346 0.00862 0.69 0.342 0.0126 1.15 1.3015 0.9712 2065485 ICCB5_000212 COCCOCOc1ccc2NC(=O)[C@H](OC(=O)OCC=C)[C@@H](NC(=O)OCC=C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J15 compound treatment 0.316 -0.0214 -1.72 0.319 -0.0104 -0.94 -1.883 -0.9597 2065486 ICCB5_000213 CCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J16 compound treatment 0.34 0.00263 0.21 0.337 0.00763 0.69 0.6389 0.8828 2065487 ICCB5_000214 COCCOCOc1ccc2NC[C@H](O)[C@@H](NC(=O)OCC=C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J17 compound treatment 0.276 -0.0614 -4.94 0.278 -0.0514 -4.66 -6.7923 -0.9996 2065488 ICCB5_000215 CCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J18 compound treatment 0.328 -0.00937 -0.75 0.317 -0.0124 -1.12 -1.3281 -0.9813 2065489 ICCB5_000216 Oc1ccc2NC(=O)[C@H](OCc3ccccc3)[C@@H](NC(=O)OCC=C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J19 compound treatment 0.324 -0.0134 -1.08 0.315 -0.0144 -1.3 -1.6842 -0.9955 2065490 ICCB5_000217 CCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J20 compound treatment 0.337 -3.75E-4 -0.03 0.33 6.25E-4 0.06 0.0188 0.2919 2065491 ICCB5_000218 O[C@@H]1[C@@H](NC(=O)OCC=C)c2cc(O)ccc2NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J21 compound treatment 0.314 -0.0234 -1.88 0.313 -0.0164 -1.49 -2.382 -0.9932 2065492 ICCB5_000219 CCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J22 compound treatment 0.361 0.0236 1.9 0.357 0.0276 2.51 3.1183 0.9907 2065493 ICCB5_000220 COCCOCOc1ccc2N=C(OCc3ccccc3)[C@H](OCc4ccccc4)[C@@H](NC(=O)OCC=C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J23 mock treatment 0.341 0.00363 0.29 0.329 -3.75E-4 -0.03 0.1823 0.6204 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 J24 positive control 0.093 -0.244 -19.68 0.089 -0.24 -21.82 -29.3434 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K01 compound treatment 0.482 0.145 11.65 0.461 0.132 11.95 16.6834 0.9999 2065494 ICCB5_000221 Oc1ccc([N+](=O)[O-])c(CC=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K02 compound treatment 0.343 0.00563 0.45 0.335 0.00563 0.51 0.6813 0.9982 2065495 ICCB5_000222 COCCOCOc1ccc(C=O)c(O[Si](C)(C)C(C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K03 compound treatment 0.434 0.0966 7.78 0.423 0.0936 8.5 11.5112 0.999 2065496 ICCB5_000223 Oc1ccc([N+](=O)[O-])c(CC=C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K04 compound treatment 0.344 0.00662 0.53 0.338 0.00863 0.78 0.9308 0.9825 2065497 ICCB5_000224 CCOC(=O)N[C@@H]1[C@H](Oc2cc(OCOCCOC)ccc12)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K05 compound treatment 0.345 0.00762 0.61 0.336 0.00663 0.6 0.8594 0.9999 2065498 ICCB5_000225 COCCOCOc1ccc([N+](=O)[O-])c(CC=C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K06 compound treatment 0.363 0.0256 2.06 0.361 0.0316 2.87 3.489 0.9869 2065499 ICCB5_000226 CCOC(=O)N[C@H]([C@@H](OS(=O)(=O)c1ccc(C)cc1)C(=O)OCC)c2ccc(OCOCCOC)cc2OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K07 compound treatment 0.332 -0.00537 -0.43 0.34 0.0106 0.96 0.3759 0.3556 2065500 ICCB5_000227 COCCOCOc1ccc([N+](=O)[O-])c(C[C@@H](O)CO)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K08 compound treatment 0.372 0.0346 2.79 0.372 0.0426 3.87 4.7075 0.9871 2065501 ICCB5_000228 CCOC(=O)[C@H](O)[C@@H](NC(=O)OCc1ccccc1)c2ccc(OCOCCOC)cc2O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K09 compound treatment 0.359 0.0216 1.74 0.349 0.0196 1.78 2.491 0.9999 2065502 ICCB5_000229 COCCOCOc1ccc([N+](=O)[O-])c(C[C@@H](O)COC(=O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K10 compound treatment 0.351 0.0136 1.1 0.341 0.0116 1.06 1.522 0.9998 2065503 ICCB5_000230 CCOC(=O)/C=C/c1ccc(OCOCCOC)cc1O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K11 compound treatment 0.348 0.0106 0.86 0.332 0.00263 0.24 0.7735 0.8709 2065504 ICCB5_000231 COCCOCOc1ccc([N+](=O)[O-])c(C[C@H](COC(=O)c2ccccc2)OS(=O)(=O)c3ccc(C)cc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K12 compound treatment 0.365 0.0276 2.22 0.37 0.0406 3.69 4.1805 0.9707 2065505 ICCB5_000232 COCCOCOc1ccc2[C@H](O[Si](C)(C)C(C)(C)C)[C@H](Oc2c1)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K13 compound treatment 0.365 0.0276 2.22 0.355 0.0256 2.33 3.2177 0.9998 2065506 ICCB5_000233 COCCOCOc1ccc2N[C@H](COC(=O)c3ccccc3)Cc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K14 compound treatment 0.366 0.0286 2.31 0.37 0.0406 3.69 4.2375 0.9744 2065507 ICCB5_000234 COCCOCOc1ccc2[C@@H]([C@H](Oc2c1)C=C)N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K15 compound treatment 0.347 0.00962 0.78 0.341 0.0116 1.06 1.2942 0.9885 2065508 ICCB5_000235 COCCOCOc1ccc2N([C@H](CO)Cc2c1)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K16 compound treatment 0.327 -0.0104 -0.84 0.307 -0.0224 -2.03 -2.0269 -0.9229 2065509 ICCB5_000236 COCCOCOc1ccc2[C@@H]([C@H](Oc2c1)C=O)N(Cc3ccc(Br)cc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K17 compound treatment 0.35 0.0126 1.02 0.349 0.0196 1.78 1.9785 0.9646 2065510 ICCB5_000237 COCCOCOc1ccc2N([C@@H](Cc2c1)C=O)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K18 compound treatment 0.374 0.0366 2.95 0.367 0.0376 3.42 4.5004 0.9973 2065511 ICCB5_000238 COCCOCOc1ccc2[C@H](NCc3ccc(Br)cc3)[C@@H](CO)Oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K19 compound treatment 0.367 0.0296 2.39 0.354 0.0246 2.24 3.2674 0.9995 2065512 ICCB5_000239 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@H](O)CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K20 compound treatment 0.358 0.0206 1.66 0.357 0.0276 2.51 2.9475 0.98 2065513 ICCB5_000240 COCCOCOc1ccc2[C@H](NCc3ccc(Br)cc3)[C@H](Oc2c1)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K21 compound treatment 0.361 0.0236 1.9 0.361 0.0316 2.87 3.3751 0.98 2065514 ICCB5_000241 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@@H](O)CC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K22 compound treatment 0.365 0.0276 2.22 0.368 0.0386 3.51 4.0521 0.9759 2065515 ICCB5_000242 COCCOCOc1ccc2[C@@H]([C@H](Oc2c1)C=C)N(Cc3ccc(Br)cc3)C(=O)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K23 mock treatment 0.338 6.25E-4 0.05 0.331 0.00163 0.15 0.1399 0.8976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 K24 positive control 0.093 -0.244 -19.68 0.089 -0.24 -21.82 -29.3434 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L01 compound treatment 0.346 0.00862 0.69 0.335 0.00563 0.51 0.8522 0.9886 2065516 ICCB5_000243 CCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L02 compound treatment 0.368 0.0306 2.47 0.363 0.0336 3.05 3.902 0.9944 2065517 ICCB5_000244 CC(=O)O[C@H](CC=C)C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc(OCc4ccccc4)ccc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L03 compound treatment 0.333 -0.00437 -0.35 0.323 -0.00637 -0.58 -0.6583 -0.9717 2065518 ICCB5_000245 CCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L04 compound treatment 0.376 0.0386 3.11 0.354 0.0246 2.24 3.7799 0.9869 2065519 ICCB5_000246 CC(=O)O[C@@H](CC=C)C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc(OCc4ccccc4)ccc3N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L05 compound treatment 0.344 0.00662 0.53 0.333 0.00363 0.33 0.6099 0.973 2065520 ICCB5_000247 CCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L06 compound treatment 0.372 0.0346 2.79 0.343 0.0136 1.24 2.8461 0.9331 2065521 ICCB5_000248 CC(=O)O[C@@H](CC=C)C[C@H]1[C@@H]2OC(C)(C)O[C@H]2c3cc(OCc4ccccc4)ccc3N1C(=O)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L07 compound treatment 0.328 -0.00937 -0.75 0.326 -0.00337 -0.31 -0.7504 -0.9211 2065522 ICCB5_000249 CCCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L08 compound treatment 0.367 0.0296 2.39 0.36 0.0306 2.78 3.6525 0.9971 2065523 ICCB5_000250 CC(=O)O[C@@H]1CC=CC(=O)N2[C@@H](C1)[C@@H]3OC(C)(C)O[C@H]3c4cc(OCc5ccccc5)ccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L09 compound treatment 0.33 -0.00737 -0.59 0.331 0.00163 0.15 -0.3156 -0.5158 2065524 ICCB5_000251 CCCCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L10 compound treatment 0.37 0.0326 2.63 0.361 0.0316 2.87 3.8875 0.999 2065525 ICCB5_000252 CC(=O)O[C@H]1CC=CC(=O)N2[C@@H](C1)[C@@H]3OC(C)(C)O[C@H]3c4cc(OCc5ccccc5)ccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L11 compound treatment 0.32 -0.0174 -1.4 0.323 -0.00637 -0.58 -1.3985 -0.9237 2065526 ICCB5_000253 CCCCCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L12 compound treatment 0.37 0.0326 2.63 0.369 0.0396 3.6 4.401 0.9881 2065527 ICCB5_000254 CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L13 compound treatment 0.337 -3.75E-4 -0.03 0.331 0.00163 0.15 0.0829 0.5509 2065528 ICCB5_000255 CCCCCCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L14 compound treatment 0.373 0.0356 2.87 0.374 0.0446 4.05 4.8928 0.9857 2065529 ICCB5_000256 CCCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L15 compound treatment 0.33 -0.00737 -0.59 0.329 -3.75E-4 -0.03 -0.444 -0.7464 2065530 ICCB5_000257 CCCCCCCCCCCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L16 compound treatment 0.312 -0.0254 -2.04 0.308 -0.0214 -1.94 -2.8168 -0.9997 2065531 ICCB5_000258 CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L17 compound treatment 0.317 -0.0204 -1.64 0.317 -0.0124 -1.12 -1.9545 -0.9829 2065532 ICCB5_000259 CCCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L18 compound treatment 0.325 -0.0124 -1.0 0.32 -0.00937 -0.85 -1.3064 -0.9969 2065533 ICCB5_000260 CCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L19 compound treatment 0.335 -0.00237 -0.19 0.331 0.00163 0.15 -0.0309 -0.1281 2065534 ICCB5_000261 CCCCCCCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L20 compound treatment 0.341 0.00363 0.29 0.331 0.00163 0.15 0.3107 0.95 2065535 ICCB5_000262 CCCCCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L21 compound treatment 0.298 -0.0394 -3.17 0.289 -0.0404 -3.66 -4.8335 -0.9974 2065536 ICCB5_000263 CCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L22 compound treatment 0.309 -0.0284 -2.28 0.302 -0.0274 -2.48 -3.3728 -0.9991 2065537 ICCB5_000264 CCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L23 mock treatment 0.345 0.00762 0.61 0.335 0.00563 0.51 0.7952 0.9958 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 L24 positive control 0.094 -0.243 -19.6 0.09 -0.239 -21.73 -29.2223 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M01 compound treatment 0.366 0.0286 2.31 0.357 0.0276 2.51 3.403 0.9991 2065538 ICCB5_000265 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@@H](CC=C)OC(=O)c3ccccc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M02 compound treatment 0.342 0.00463 0.37 0.334 0.00463 0.42 0.5602 0.9982 2065539 ICCB5_000266 CCOC(=O)/C=C\Cc1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M03 compound treatment 0.361 0.0236 1.9 0.361 0.0316 2.87 3.3751 0.98 2065540 ICCB5_000267 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@H](CC=C)OC(=O)c3ccccc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M04 compound treatment 0.344 0.00662 0.53 0.338 0.00863 0.78 0.9308 0.9825 2065541 ICCB5_000268 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)Cc2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M05 compound treatment 0.364 0.0266 2.14 0.354 0.0246 2.24 3.0966 0.9998 2065542 ICCB5_000269 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@@H](CC=C)O[Si](C)(C)C(C)(C)C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M06 compound treatment 0.379 0.0416 3.35 0.369 0.0396 3.6 4.9135 0.9994 2065380 ICCB5_000270 CCOC(=O)/C=C/c1cc2OCOc2cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M07 compound treatment 0.37 0.0326 2.63 0.37 0.0406 3.69 4.4652 0.9862 2065543 ICCB5_000271 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@H](CC=C)O[Si](C)(C)C(C)(C)C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M08 compound treatment 0.365 0.0276 2.22 0.352 0.0226 2.05 3.0252 0.9992 2065544 ICCB5_000272 CCOC(=O)[C@H](O)[C@@H](NC(=O)OCc1ccccc1)c2cc3OCOc3cc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M09 compound treatment 0.362 0.0246 1.98 0.36 0.0306 2.78 3.3678 0.9863 2065545 ICCB5_000273 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@H](CC=C)OC(=O)C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M10 compound treatment 0.329 -0.00837 -0.67 0.321 -0.00837 -0.76 -1.0144 -0.9982 2065546 ICCB5_000274 CCOC(=O)[C@@H]1OC(C)(C)N([C@H]1c2cc3OCOc3cc2[N+](=O)[O-])C(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M11 compound treatment 0.307 -0.0304 -2.45 0.307 -0.0224 -2.03 -3.1657 -0.9957 2065547 ICCB5_000275 Oc1ccc2N([C@@H](Cc2c1)[C@@H](CC=C)OC(=O)c3ccccc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M12 compound treatment 0.35 0.0126 1.02 0.343 0.0136 1.24 1.5934 0.9953 2065548 ICCB5_000276 CC1(C)O[C@@H](CO)[C@@H](N1C(=O)OCc2ccccc2)c3cc4OCOc4cc3[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M13 compound treatment 0.359 0.0216 1.74 0.371 0.0416 3.78 3.903 0.9382 2065549 ICCB5_000277 COCCOCOc1ccc2N[C@@H](Cc2c1)[C@@H](CC=C)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M14 compound treatment 0.332 -0.00537 -0.43 0.33 6.25E-4 0.06 -0.2659 -0.6092 2065550 ICCB5_000278 CCOC(=O)[C@H]1Nc2cc3OCOc3cc2C[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M15 compound treatment 0.375 0.0376 3.03 0.361 0.0316 2.87 4.1723 0.9996 2065551 ICCB5_000279 COCCOCOc1ccc2N[C@@H](Cc2c1)[C@H](CC=C)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M16 compound treatment 0.328 -0.00937 -0.75 0.318 -0.0114 -1.03 -1.2639 -0.9882 2065552 ICCB5_000280 CCOC(=O)[C@@H]1[C@@H](O)Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M17 compound treatment 0.362 0.0246 1.98 0.36 0.0306 2.78 3.3678 0.9863 2065553 ICCB5_000281 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@@H](CC=C)O[Si](C)(C)C(C)(C)C)C(=O)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M18 compound treatment 0.337 -3.75E-4 -0.03 0.334 0.00463 0.42 0.2755 0.6546 2065554 ICCB5_000282 CCOC(=O)[C@@H]1[C@H](Cc2cc3OCOc3cc2N1C(=O)C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M19 compound treatment 0.372 0.0346 2.79 0.367 0.0376 3.42 4.3865 0.9949 2065555 ICCB5_000283 COCCOCOc1ccc2N([C@@H](Cc2c1)[C@H](CC=C)O[Si](C)(C)C(C)(C)C)C(=O)C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M20 compound treatment 0.365 0.0276 2.22 0.354 0.0246 2.24 3.1535 1.0 2065556 ICCB5_000284 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H](O)Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M21 compound treatment 0.361 0.0236 1.9 0.359 0.0296 2.69 3.2467 0.9856 2065557 ICCB5_000285 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@H](CC=CC3=O)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M22 compound treatment 0.336 -0.00137 -0.11 0.329 -3.75E-4 -0.03 -0.1024 -0.8837 2065558 ICCB5_000286 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](Cc2cc3OCOc3cc2N1C(=O)OCC=C)OC(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M23 mock treatment 0.335 -0.00237 -0.19 0.328 -0.00137 -0.12 -0.2235 -0.9786 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 M24 positive control 0.093 -0.244 -19.68 0.09 -0.239 -21.73 -29.2792 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N01 compound treatment 0.331 -0.00637 -0.51 0.327 -0.00237 -0.22 -0.5154 -0.9257 2065559 ICCB5_000287 CCCCCCCCC(=O)O/C=C/c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N02 compound treatment 0.339 0.00163 0.13 0.331 0.00163 0.15 0.1968 0.9982 2065560 ICCB5_000288 CCCCCCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N03 compound treatment 0.32 -0.0174 -1.4 0.303 -0.0264 -2.39 -2.6822 -0.9673 2065561 ICCB5_000289 CCCCCCCCCCCCCCC(=O)O/C=C\c1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N04 compound treatment 0.332 -0.00537 -0.43 0.328 -0.00137 -0.12 -0.3943 -0.8753 2065562 ICCB5_000290 CCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N05 compound treatment 0.337 -3.75E-4 -0.03 0.331 0.00163 0.15 0.0829 0.5509 3057099 ICCB5_000291 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N06 compound treatment 0.348 0.0106 0.86 0.343 0.0136 1.24 1.4795 0.9838 2065563 ICCB5_000292 CCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N07 compound treatment 0.333 -0.00437 -0.35 0.338 0.00863 0.78 0.3045 0.3547 3057100 ICCB5_000293 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N08 compound treatment 0.317 -0.0204 -1.64 0.321 -0.00837 -0.76 -1.6977 -0.9389 2065564 ICCB5_000294 CCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N09 compound treatment 0.334 -0.00337 -0.27 0.337 0.00763 0.69 0.2972 0.3997 3176076 ICCB5_000295 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N10 compound treatment 0.368 0.0306 2.47 0.362 0.0326 2.96 3.8379 0.9959 2065565 ICCB5_000296 CCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N11 compound treatment 0.36 0.0226 1.82 0.359 0.0296 2.69 3.1898 0.982 2065566 ICCB5_000297 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N12 compound treatment 0.354 0.0166 1.34 0.35 0.0206 1.87 2.2705 0.9865 2065567 ICCB5_000298 CCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N13 compound treatment 0.362 0.0246 1.98 0.357 0.0276 2.51 3.1753 0.9932 2065568 ICCB5_000299 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N14 compound treatment 0.374 0.0366 2.95 0.375 0.0456 4.14 5.0139 0.9862 2065569 ICCB5_000300 CCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N15 compound treatment 0.334 -0.00337 -0.27 0.332 0.00263 0.24 -0.0237 -0.0655 2065570 ICCB5_000301 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N16 compound treatment 0.362 0.0246 1.98 0.345 0.0156 1.42 2.4051 0.9865 2065571 ICCB5_000302 CCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N17 compound treatment 0.33 -0.00737 -0.59 0.322 -0.00737 -0.67 -0.8933 -0.9982 2065572 ICCB5_000303 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N18 compound treatment 0.378 0.0406 3.27 0.379 0.0496 4.5 5.4984 0.9877 2065573 ICCB5_000304 CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N19 compound treatment 0.332 -0.00537 -0.43 0.332 0.00263 0.24 -0.1376 -0.2784 2065574 ICCB5_000305 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N20 compound treatment 0.366 0.0286 2.31 0.363 0.0336 3.05 3.7882 0.9904 2065575 ICCB5_000306 CCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N21 compound treatment 0.341 0.00363 0.29 0.332 0.00263 0.24 0.3749 0.9949 2065576 ICCB5_000307 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N22 compound treatment 0.373 0.0356 2.87 0.374 0.0446 4.05 4.8928 0.9857 2065577 ICCB5_000308 CCCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N23 mock treatment 0.342 0.00463 0.37 0.332 0.00263 0.24 0.4318 0.9767 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 N24 positive control 0.093 -0.244 -19.68 0.091 -0.238 -21.64 -29.215 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O01 compound treatment 0.374 0.0366 2.95 0.357 0.0276 2.51 3.8586 0.9967 2065578 ICCB5_000309 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@@H](CC=CC3=O)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O02 compound treatment 0.346 0.00862 0.69 0.336 0.00663 0.6 0.9163 0.9974 2065579 ICCB5_000310 OC[C@@H]1[C@@H](O)Cc2cc3OCOc3cc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O03 compound treatment 0.343 0.00563 0.45 0.34 0.0106 0.96 1.0023 0.9406 2065580 ICCB5_000311 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@@H](C[C@H](CC3=O)Sc4ccccc4)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O04 compound treatment 0.344 0.00662 0.53 0.332 0.00263 0.24 0.5457 0.934 2065581 ICCB5_000312 C=CCOC(=O)OC[C@@H]1[C@H](Cc2cc3OCOc3cc2N1C(=O)OCC=C)OC(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O05 compound treatment 0.365 0.0276 2.22 0.349 0.0196 1.78 2.8326 0.9939 2065582 ICCB5_000313 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@H](C[C@@H](CC3=O)Sc4ccccc4)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O06 compound treatment 0.341 0.00363 0.29 0.332 0.00263 0.24 0.3749 0.9949 2065583 ICCB5_000314 CC(=O)O[C@H]1Cc2cc3OCOc3cc2N([C@@H]1COC(=O)OCC=C)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O07 compound treatment 0.334 -0.00337 -0.27 0.34 0.0106 0.96 0.4898 0.4888 2065584 ICCB5_000315 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@H](O)CC=CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O08 compound treatment 0.338 6.25E-4 0.05 0.332 0.00263 0.24 0.2041 0.838 2065585 ICCB5_000316 CC(C)(C)C(=O)OC[C@@H]1[C@H](Cc2cc3OCOc3cc2N1CC=C)O[Si](C)(C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O09 compound treatment 0.341 0.00363 0.29 0.339 0.00963 0.87 0.8242 0.8947 2065586 ICCB5_000317 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@@H](O)CC=CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O10 compound treatment 0.375 0.0376 3.03 0.369 0.0396 3.6 4.6857 0.9964 2065587 ICCB5_000318 CCOC(=O)/C=C/Cc1cc(OCOCCOC)ccc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O11 compound treatment 0.376 0.0386 3.11 0.37 0.0406 3.69 4.8069 0.9964 2065588 ICCB5_000319 COCCOCOc1ccc2N3[C@@H](Cc2c1)[C@@H]4C[C@@H](C[Si](C)(C)O4)CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O12 compound treatment 0.384 0.0466 3.75 0.366 0.0366 3.32 5.0056 0.9982 2065589 ICCB5_000320 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)Cc2cc(OCOCCOC)ccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O13 compound treatment 0.359 0.0216 1.74 0.354 0.0246 2.24 2.8119 0.9924 2065590 ICCB5_000321 COCCOCOc1ccc2N3[C@@H](Cc2c1)C=CC=CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O14 compound treatment 0.365 0.0276 2.22 0.359 0.0296 2.69 3.4745 0.9956 2065591 ICCB5_000322 CCOC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)Cc2cc(OC3CCCCO3)ccc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O15 compound treatment 0.378 0.0406 3.27 0.354 0.0246 2.24 3.8938 0.9828 2065592 ICCB5_000323 OCCCOc1ccc2N([C@@H](Cc2c1)[C@@H](CC=C)OC(=O)c3ccccc3)C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O16 compound treatment 0.35 0.0126 1.02 0.35 0.0206 1.87 2.0427 0.9588 2065593 ICCB5_000324 CCOC(=O)/C=C/c1cc(O)ccc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O17 compound treatment 0.372 0.0346 2.79 0.372 0.0426 3.87 4.7075 0.9871 2065594 ICCB5_000325 CCOC(=O)/C=C/[C@@H]1Cc2cc(OCOCCOC)ccc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O18 compound treatment 0.368 0.0306 2.47 0.355 0.0256 2.33 3.3886 0.9996 2065595 ICCB5_000326 CCOC(=O)/C=C/c1cc(OCOCCOC)ccc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O19 compound treatment 0.347 0.00962 0.78 0.342 0.0126 1.15 1.3584 0.9819 2065596 ICCB5_000327 CCOC(=O)/C=C/[C@@H]1Cc2ccccc2N1C(=O)OCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O20 compound treatment 0.491 0.154 12.37 0.478 0.149 13.49 18.287 0.9991 2065371 ICCB5_000328 CCOC(=O)[C@H](O)[C@@H](NC(=O)OCc1ccccc1)c2cc(OCOCCOC)ccc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O21 compound treatment 0.359 0.0216 1.74 0.344 0.0146 1.33 2.1701 0.991 2065597 ICCB5_000329 CCOC(=O)/C=C/[C@@H]1Cc2ccccc2N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O22 compound treatment 0.641 0.304 24.45 0.638 0.309 28.01 37.0978 0.9977 2065598 ICCB5_000330 CCOC(=O)[C@H](OC(C)C)[C@@H](N(C(C)C)C(=O)OCc1ccccc1)c2cc(OCOCCOC)ccc2[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O23 mock treatment 0.329 -0.00837 -0.67 0.325 -0.00437 -0.4 -0.7577 -0.9681 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 O24 positive control 0.094 -0.243 -19.6 0.092 -0.237 -21.55 -29.0939 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P01 compound treatment 0.339 0.00163 0.13 0.342 0.0126 1.15 0.9029 0.7828 2065599 ICCB5_000331 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P02 compound treatment 0.371 0.0336 2.71 0.369 0.0396 3.6 4.458 0.9902 2065600 ICCB5_000332 CCCCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P03 compound treatment 0.328 -0.00937 -0.75 0.34 0.0106 0.96 0.1481 0.121 2065601 ICCB5_000333 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P04 compound treatment 0.36 0.0226 1.82 0.359 0.0296 2.69 3.1898 0.982 2065602 ICCB5_000334 CCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P05 compound treatment 0.334 -0.00337 -0.27 0.324 -0.00537 -0.49 -0.5372 -0.9618 2065603 ICCB5_000335 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P06 compound treatment 0.325 -0.0124 -1.0 0.335 0.00563 0.51 -0.3436 -0.3069 2065604 ICCB5_000336 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P07 compound treatment 0.328 -0.00937 -0.75 0.33 6.25E-4 0.06 -0.4937 -0.6521 2065605 ICCB5_000337 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P08 compound treatment 0.354 0.0166 1.34 0.353 0.0236 2.14 2.463 0.9743 2065606 ICCB5_000338 CCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P09 compound treatment 0.332 -0.00537 -0.43 0.333 0.00363 0.33 -0.0734 -0.135 2065607 ICCB5_000339 CCCCNC(=O)C(OC(=O)c1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P10 compound treatment 0.363 0.0256 2.06 0.36 0.0306 2.78 3.4248 0.9892 2065608 ICCB5_000340 CCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P11 compound treatment 0.324 -0.0134 -1.08 0.318 -0.0114 -1.03 -1.4917 -0.9998 2065609 ICCB5_000341 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P12 compound treatment 0.359 0.0216 1.74 0.356 0.0266 2.42 2.9403 0.9871 2065610 ICCB5_000342 CCCCCC/C=C\CCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P13 compound treatment 0.329 -0.00837 -0.67 0.326 -0.00337 -0.31 -0.6935 -0.9362 2065611 ICCB5_000343 COc1ccc(CN2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P14 compound treatment 0.367 0.0296 2.39 0.361 0.0316 2.87 3.7167 0.9958 2065612 ICCB5_000344 CCCCCCCCCCC/C=C\CCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P15 compound treatment 0.325 -0.0124 -1.0 0.327 -0.00237 -0.22 -0.8571 -0.8406 2065613 ICCB5_000345 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccc(OC)cc4)C(=O)C13)C(=O)NCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P16 compound treatment 0.365 0.0276 2.22 0.359 0.0296 2.69 3.4745 0.9956 2065614 ICCB5_000346 CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P17 compound treatment 0.329 -0.00837 -0.67 0.324 -0.00537 -0.49 -0.8219 -0.9874 2065615 ICCB5_000347 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P18 compound treatment 0.357 0.0196 1.58 0.364 0.0346 3.14 3.3399 0.9494 2065616 ICCB5_000348 CCCC/C=C\CCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P19 compound treatment 0.359 0.0216 1.74 0.377 0.0476 4.32 4.2882 0.9201 2065617 ICCB5_000349 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O[C@H]([C@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P20 compound treatment 0.359 0.0216 1.74 0.357 0.0276 2.51 3.0045 0.9841 2065618 ICCB5_000350 CCCCCCCC/C=C\CCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P21 compound treatment 0.389 0.0516 4.16 0.383 0.0536 4.87 6.3815 0.9969 2065619 ICCB5_000351 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)[C@@]4(O[C@@H]5C=C4)[C@@H]([C@H]5C(=O)O[C@H]([C@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P22 compound treatment 0.356 0.0186 1.5 0.356 0.0266 2.42 2.7695 0.9737 2065620 ICCB5_000352 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P23 mock treatment 0.336 -0.00137 -0.11 0.329 -3.75E-4 -0.03 -0.1024 -0.8837 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1363 P24 positive control 0.096 -0.241 -19.44 0.093 -0.236 -21.46 -28.9158 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A01 compound treatment 0.314 -0.0101 -0.82 0.32 -0.0153 -1.39 -1.5607 -0.9675 1023263 Maybridge3_000001 OC(=O)c1ccc(Br)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A02 compound treatment 0.324 -1.25E-4 -0.01 0.324 -0.0113 -1.03 -0.7345 -0.714 2075164 Maybridge3_000002 CC(C)(C)OC(=O)NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A03 compound treatment 0.31 -0.0141 -1.14 0.315 -0.0203 -1.85 -2.1094 -0.973 2075165 Maybridge3_000003 CC(C)(C)OC(=O)N1CCC(N)(CC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A04 compound treatment 0.312 -0.0121 -0.98 0.314 -0.0213 -1.94 -2.0597 -0.9497 1125505 Maybridge3_000004 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A05 compound treatment 0.309 -0.0151 -1.22 0.312 -0.0233 -2.12 -2.3589 -0.9655 2075166 Maybridge3_000005 FC(F)(F)c1ccnc(SCC(=O)c2cccnc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A06 compound treatment 0.306 -0.0181 -1.46 0.325 -0.0103 -0.94 -1.6953 -0.9771 1209791 Maybridge3_000006 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A07 compound treatment 0.314 -0.0101 -0.82 0.334 -0.00133 -0.12 -0.6621 -0.8033 2075167 Maybridge3_000007 OC(COc1ccc(F)cc1)CN2CCN(CC2)c3nccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A08 compound treatment 0.299 -0.0251 -2.02 0.311 -0.0243 -2.21 -2.9925 -0.999 2075168 Maybridge3_000008 Fc1cccc(Cl)c1CN2CCN(CCCNc3nccc(n3)C(F)(F)F)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A09 compound treatment 0.303 -0.0211 -1.7 0.306 -0.0293 -2.66 -3.0856 -0.9766 2075169 Maybridge3_000009 CC(=O)Nc1ccc(cc1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A10 compound treatment 0.324 -1.25E-4 -0.01 0.316 -0.0193 -1.75 -1.248 -0.7112 1620264 Maybridge3_000010 Cc1nc(nc(N2CCCN(Cc3ccc(F)cc3)CC2)c1Cl)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A11 compound treatment 0.307 -0.0171 -1.38 0.316 -0.0193 -1.75 -2.216 -0.9929 2075170 Maybridge3_000011 Cc1nc(ccc1c2nnc(SCc3cc(F)cc(F)c3)o2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A12 compound treatment 0.304 -0.0201 -1.62 0.322 -0.0133 -1.21 -2.0017 -0.9897 2075171 Maybridge3_000012 Clc1cccc(c1Cl)S(=O)(=O)NCCCN2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A13 compound treatment 0.298 -0.0261 -2.1 0.3 -0.0353 -3.21 -3.7555 -0.9791 1658739 Maybridge3_000013 OC(CNC1CCN(Cc2ccccc2)CC1)CSc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A14 compound treatment 0.313 -0.0111 -0.9 0.31 -0.0253 -2.3 -2.2595 -0.9156 2075172 Maybridge3_000014 Clc1ccc(OCC(=O)NC2=NCCS2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A15 compound treatment 0.314 -0.0101 -0.82 0.316 -0.0193 -1.75 -1.8174 -0.9392 1464531 Maybridge3_000015 CCOC(=O)c1cc(C#N)c(C)nc1N(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A16 compound treatment 0.31 -0.0141 -1.14 0.317 -0.0183 -1.66 -1.981 -0.9828 2075173 Maybridge3_000016 COc1cc(/C=N/c2cc(C)ccc2NC(=O)C)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A17 compound treatment 0.321 -0.00312 -0.25 0.312 -0.0233 -2.12 -1.6756 -0.7856 2075174 Maybridge3_000017 FC(F)(F)c1ccnc(NCCNS(=O)(=O)c2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A18 compound treatment 0.311 -0.0131 -1.06 0.331 -0.00433 -0.39 -1.0255 -0.9093 1167525 Maybridge3_000018 OC(=O)CSC1(CCCCCC1)SCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A19 compound treatment 0.312 -0.0121 -0.98 0.317 -0.0183 -1.66 -1.8671 -0.9677 2075175 Maybridge3_000019 Cc1oc(cc1C(=O)O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A20 compound treatment 0.31 -0.0141 -1.14 0.319 -0.0163 -1.48 -1.8526 -0.9914 1575563 Maybridge3_000020 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A21 compound treatment 0.308 -0.0161 -1.3 0.313 -0.0223 -2.03 -2.3516 -0.9768 2075176 Maybridge3_000021 Cc1nc(ccc1C(=O)NCc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A22 compound treatment 0.31 -0.0141 -1.14 0.316 -0.0193 -1.75 -2.0452 -0.978 1510905 Maybridge3_000022 Clc1ccc(cc1)S(=O)(=O)N(CCc2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A23 mock treatment 0.318 -0.00612 -0.49 0.313 -0.0223 -2.03 -1.7822 -0.8542 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 A24 positive control 0.082 -0.242 -19.5 0.082 -0.253 -23.0 -30.047 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B01 compound treatment 0.337 0.0129 1.04 0.337 0.00167 0.15 0.8401 0.8018 2075177 Maybridge3_000023 Fc1cccc(NCc2ccc3OCOc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B02 compound treatment 0.168 -0.156 -12.57 0.189 -0.146 -13.28 -18.2823 -0.9996 2075178 Maybridge3_000024 Brc1ccc(cc1)C2=CSc3ccccc3N2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B03 compound treatment 0.333 0.00888 0.71 0.342 0.00667 0.61 0.9333 0.9966 2075179 Maybridge3_000025 Cn1nc(CC#N)c(C#N)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B04 compound treatment 0.34 0.0159 1.28 0.346 0.0107 0.97 1.5886 0.9906 2075180 Maybridge3_000026 CCOc1ccccc1NC(=O)Oc2ccc(F)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B05 compound treatment 0.323 -0.00112 -0.09 0.335 -3.33E-4 -0.03 -0.0855 -0.8947 2075181 Maybridge3_000027 COc1ccc(cc1)/C(=C/c2cccs2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B06 compound treatment 0.331 0.00688 0.55 0.338 0.00267 0.24 0.5626 0.9312 1568831 Maybridge3_000028 Fc1cccc2nc(oc(=O)c12)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B07 compound treatment 0.329 0.00488 0.39 0.332 -0.00333 -0.3 0.0636 0.1284 1718012 Maybridge3_000029 COc1cc2CCNC(c3ccccc3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B08 compound treatment 0.325 8.75E-4 0.07 0.335 -3.33E-4 -0.03 0.0284 0.3707 2075182 Maybridge3_000030 COc1ccc(/N=C\2/NC(C)(C)C(=C)S2)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B09 compound treatment 0.335 0.0109 0.88 0.336 6.67E-4 0.06 0.662 0.7542 1314153 Maybridge3_000031 Nc1cccc(Cl)c1Oc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B10 compound treatment 0.38 0.0559 4.5 0.371 0.0357 3.24 5.4708 0.987 2075183 Maybridge3_000032 COC(=O)/C=C/1\S/C(=N\c2cccc(SC)c2)/N(C1=O)c3cccc(SC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B11 compound treatment 0.329 0.00488 0.39 0.333 -0.00233 -0.21 0.1278 0.2866 1136610 Maybridge3_000033 O=C(Oc1ccccc1)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B12 compound treatment 0.333 0.00888 0.71 0.337 0.00167 0.15 0.6123 0.8382 2075184 Maybridge3_000034 CC(=O)Nc1cc2cc(NC(=O)C(F)(F)F)ccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B13 compound treatment 0.327 0.00288 0.23 0.338 0.00267 0.24 0.3349 0.9998 1365408 Maybridge3_000035 Cc1ccc2cccc(OC(=O)c3cccnc3Oc4ccccc4)c2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B14 compound treatment 0.328 0.00388 0.31 0.342 0.00667 0.61 0.6485 0.9525 2075185 Maybridge3_000036 FC(F)(F)C(=O)Nc1nnc(s1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B15 compound treatment 0.337 0.0129 1.04 0.345 0.00967 0.88 1.3536 0.9966 2075186 Maybridge3_000037 CCOC(=O)C1=CNc2ccccc2N=C1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B16 compound treatment 0.332 0.00788 0.63 0.339 0.00367 0.33 0.6838 0.9547 1144609 Maybridge3_000038 Fc1ccc(NC(=O)Cc2ncon2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B17 compound treatment 0.33 0.00588 0.47 0.341 0.00567 0.51 0.6982 0.9991 2075187 Maybridge3_000039 CCOC(=O)c1cc(Cl)c(NC(=O)C(F)(F)F)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B18 compound treatment 0.333 0.00888 0.71 0.337 0.00167 0.15 0.6123 0.8382 2075188 Maybridge3_000040 Cn1c(nc(=O)c2ccccc12)c3cc(Br)cs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B19 compound treatment 0.331 0.00688 0.55 0.336 6.67E-4 0.06 0.4343 0.7798 2075189 Maybridge3_000041 Fc1ccc(cc1Cl)C(=O)Nc2nnc(s2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B20 compound treatment 0.334 0.00988 0.8 0.336 6.67E-4 0.06 0.6051 0.7587 2075190 Maybridge3_000042 CC(C)(C)c1nnc(N/C=N/O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B21 compound treatment 0.336 0.0119 0.96 0.339 0.00367 0.33 0.9115 0.9002 2075191 Maybridge3_000043 C/C=C(\C)/c1nnc(NCC(C)(C)C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B22 compound treatment 0.329 0.00488 0.39 0.338 0.00267 0.24 0.4487 0.973 1193479 Maybridge3_000044 O=C(NCC1CC1)c2ccccc2NC(=O)c3cc4ccccc4oc3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B23 mock treatment 0.322 -0.00212 -0.17 0.337 0.00167 0.15 -0.014 -0.0614 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 B24 positive control 0.082 -0.242 -19.5 0.082 -0.253 -23.0 -30.047 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C01 compound treatment 0.333 0.00888 0.71 0.335 -3.33E-4 -0.03 0.484 0.6766 342762 Maybridge3_000045 COc1ccc2[nH]cc(CCN(C)C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C02 compound treatment 0.336 0.0119 0.96 0.336 6.67E-4 0.06 0.719 0.7504 1121244 Maybridge3_000046 CCOC(=O)c1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C03 compound treatment 0.317 -0.00712 -0.57 0.327 -0.00833 -0.76 -0.9406 -0.9907 1252601 Maybridge3_000047 CCN(CC)S(=O)(=O)c1ccc(s1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C04 compound treatment 0.32 -0.00412 -0.33 0.334 -0.00133 -0.12 -0.3205 -0.9065 2075192 Maybridge3_000048 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C05 compound treatment 0.322 -0.00212 -0.17 0.327 -0.00833 -0.76 -0.6559 -0.8457 2075193 Maybridge3_000049 FC(F)(F)c1ccnc(SCC(=O)Nc2ccc(Br)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C06 compound treatment 0.325 8.75E-4 0.07 0.335 -3.33E-4 -0.03 0.0284 0.3707 1566490 Maybridge3_000050 CCN(CC)S(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C07 compound treatment 0.32 -0.00412 -0.33 0.329 -0.00633 -0.57 -0.6414 -0.966 1513220 Maybridge3_000051 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C08 compound treatment 0.322 -0.00212 -0.17 0.332 -0.00333 -0.3 -0.3349 -0.9636 1121829 Maybridge3_000052 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C09 compound treatment 0.328 0.00388 0.31 0.331 -0.00433 -0.39 -0.0575 -0.1145 1309044 Maybridge3_000053 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C10 compound treatment 0.313 -0.0111 -0.9 0.327 -0.00833 -0.76 -1.1683 -0.9965 1606977 Maybridge3_000054 COc1cccc(CC(=O)Nc2ccc(cc2)c3csc(C)n3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C11 compound treatment 0.319 -0.00512 -0.41 0.326 -0.00933 -0.85 -0.8909 -0.9454 2075194 Maybridge3_000055 Cc1nc(ccc1c2nnc(SCC=C)o2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C12 compound treatment 0.331 0.00688 0.55 0.337 0.00167 0.15 0.4984 0.8685 2075195 Maybridge3_000056 FC(F)(F)c1ccnc(n1)N2CCC(CC2)N3C(=O)CC4(CCCC4)C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C13 compound treatment 0.319 -0.00512 -0.41 0.322 -0.0133 -1.21 -1.1476 -0.8975 2075196 Maybridge3_000057 Cc1nc(ccc1C(=O)Oc2ccc3OCOc3c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C14 compound treatment 0.321 -0.00312 -0.25 0.327 -0.00833 -0.76 -0.7128 -0.8942 2075197 Maybridge3_000058 O=C(Cc1ccccc1)NC2=NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C15 compound treatment 0.32 -0.00412 -0.33 0.331 -0.00433 -0.39 -0.513 -0.9965 2075198 Maybridge3_000059 Cc1nc(ccc1C(=O)NCCc2cccs2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C16 compound treatment 0.321 -0.00312 -0.25 0.333 -0.00233 -0.21 -0.3277 -0.9963 2075199 Maybridge3_000060 CC(=O)Nc1ccc(C)cc1/N=C/c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C17 compound treatment 0.317 -0.00712 -0.57 0.338 0.00267 0.24 -0.2345 -0.3766 2075200 Maybridge3_000061 FC(F)(F)c1cccc(c1)C(=O)NCCNc2nccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C18 compound treatment 0.323 -0.00112 -0.09 0.334 -0.00133 -0.12 -0.1496 -0.9898 2075201 Maybridge3_000062 CS(=O)(=O)N1CCc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C19 compound treatment 0.325 8.75E-4 0.07 0.336 6.67E-4 0.06 0.0926 0.9971 1199320 Maybridge3_000063 CCCc1cnc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C20 compound treatment 0.326 0.00188 0.15 0.328 -0.00733 -0.67 -0.3639 -0.5332 2075202 Maybridge3_000064 CCOC(=O)c1ccc(/N=C/c2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C21 compound treatment 0.33 0.00588 0.47 0.335 -3.33E-4 -0.03 0.3131 0.6605 2075203 Maybridge3_000065 Cc1nc(ccc1C(=O)NCCNc2cccc(n2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C22 compound treatment 0.324 -1.25E-4 -0.01 0.329 -0.00633 -0.57 -0.4136 -0.7194 2075204 Maybridge3_000066 C/C=C(\C)/C(=O)Nc1cc(C)ccc1n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C23 mock treatment 0.315 -0.00912 -0.73 0.335 -3.33E-4 -0.03 -0.541 -0.7356 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 C24 positive control 0.082 -0.242 -19.5 0.084 -0.251 -22.81 -29.9186 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D01 compound treatment 0.337 0.0129 1.04 0.343 0.00767 0.7 1.2252 0.9812 1722143 Maybridge3_000067 C(Cc1ccccn1)c2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D02 compound treatment 0.333 0.00888 0.71 0.338 0.00267 0.24 0.6765 0.8966 1604322 Maybridge3_000068 Fc1ccccc1C(=O)NCC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D03 compound treatment 0.375 0.0509 4.1 0.386 0.0507 4.6 6.1489 0.9983 2075205 Maybridge3_000069 Oc1c(Cl)cc(Cl)cc1/C=N/c2c(C#N)c(CC#N)nn2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D04 compound treatment 0.321 -0.00312 -0.25 0.332 -0.00333 -0.3 -0.3919 -0.9958 2075206 Maybridge3_000070 Fc1ccc(OC(=O)c2cc3ccccc3s2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D05 compound treatment 0.318 -0.00612 -0.49 0.324 -0.0113 -1.03 -1.0762 -0.9433 2075207 Maybridge3_000071 Cc1ccc(cc1)/C(=C/c2c(F)cccc2Cl)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D06 compound treatment 0.325 8.75E-4 0.07 0.334 -0.00133 -0.12 -0.0358 -0.2553 2075208 Maybridge3_000072 Fc1cccc2nc(oc(=O)c12)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D07 compound treatment 0.323 -0.00112 -0.09 0.334 -0.00133 -0.12 -0.1496 -0.9898 2075209 Maybridge3_000073 FC(F)(F)C(=O)Nc1ccc(Br)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D08 compound treatment 0.329 0.00488 0.39 0.339 0.00367 0.33 0.5129 0.9966 2075210 Maybridge3_000074 CC(=O)Nc1ccc(F)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D09 compound treatment 0.336 0.0119 0.96 0.349 0.0137 1.24 1.5534 0.9917 1718995 Maybridge3_000075 COc1ccc2cc(oc2c1)C(=O)c3ccc(Cl)c(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D10 compound treatment 0.328 0.00388 0.31 0.335 -3.33E-4 -0.03 0.1993 0.6356 2075211 Maybridge3_000076 Cc1ncc(CSc2nccc(O)n2)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D11 compound treatment 0.33 0.00588 0.47 0.34 0.00467 0.42 0.6341 0.9985 1104602 Maybridge3_000077 COC1(C)CNc2ccccc2C(=O)N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D12 compound treatment 0.331 0.00688 0.55 0.339 0.00367 0.33 0.6268 0.9704 2075212 Maybridge3_000078 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D13 compound treatment 0.267 -0.0571 -4.6 0.3 -0.0353 -3.21 -5.5206 -0.9845 1064547 Maybridge3_000079 Cc1ccc(cc1)C(=O)CCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D14 compound treatment 0.324 -1.25E-4 -0.01 0.337 0.00167 0.15 0.0999 0.6586 1517249 Maybridge3_000080 Fc1cccc(CSc2ncc3ccccn23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D15 compound treatment 0.343 0.0189 1.52 0.351 0.0157 1.42 2.0803 0.9994 1223097 Maybridge3_000081 Cn1sc(=O)c2ccc(cc12)S(=O)(=O)NCCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D16 compound treatment 0.335 0.0109 0.88 0.35 0.0147 1.33 1.5606 0.9794 1283484 Maybridge3_000082 O=c1c2cccnc2oc3ccc(cc13)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D17 compound treatment 0.33 0.00588 0.47 0.333 -0.00233 -0.21 0.1848 0.3564 2075213 Maybridge3_000083 Cc1onc(c1C(=O)NCCSC2=NCCN2)c3c(Cl)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D18 compound treatment 0.332 0.00788 0.63 0.338 0.00267 0.24 0.6196 0.9128 2075214 Maybridge3_000084 Brc1csc(c1)c2nc(=O)c3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D19 compound treatment 0.335 0.0109 0.88 0.34 0.00467 0.42 0.9188 0.9445 2075215 Maybridge3_000085 CC(=Cc1nc2cccc(F)c2c(=O)o1)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D20 compound treatment 0.335 0.0109 0.88 0.342 0.00667 0.61 1.0471 0.9837 1322517 Maybridge3_000086 Fc1ccc(NC(=O)Cc2nn[nH]n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D21 compound treatment 0.337 0.0129 1.04 0.336 6.67E-4 0.06 0.7759 0.7471 2075216 Maybridge3_000087 Cc1nnc(NCC(C)(C)C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D22 compound treatment 0.346 0.0219 1.76 0.353 0.0177 1.6 2.3795 0.9989 2075217 Maybridge3_000088 CCCc1ccc(cc1)c2ccc(cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D23 mock treatment 0.324 -1.25E-4 -0.01 0.332 -0.00333 -0.3 -0.2211 -0.7302 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 D24 positive control 0.085 -0.239 -19.26 0.085 -0.25 -22.72 -29.6836 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E01 compound treatment 0.336 0.0119 0.96 0.34 0.00467 0.42 0.9757 0.9329 1050973 Maybridge3_000089 Cc1ccc2[nH]cc(CCN)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E02 compound treatment 0.333 0.00888 0.71 0.339 0.00367 0.33 0.7407 0.9395 2075218 Maybridge3_000090 Brc1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E03 compound treatment 0.325 8.75E-4 0.07 0.334 -0.00133 -0.12 -0.0358 -0.2553 1123698 Maybridge3_000091 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E04 compound treatment 0.352 0.0279 2.24 0.358 0.0227 2.06 3.0421 0.9991 1231775 Maybridge3_000092 CCOC(=O)c1c(NC(=O)CCC(=O)O)sc(C)c1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E05 compound treatment 0.341 0.0169 1.36 0.354 0.0187 1.69 2.159 0.994 2075219 Maybridge3_000093 OC(=O)CSCC(=O)Nc1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E06 compound treatment 0.325 8.75E-4 0.07 0.345 0.00967 0.88 0.6703 0.7614 1696466 Maybridge3_000094 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)N4CCSCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E07 compound treatment 0.334 0.00988 0.8 0.344 0.00867 0.79 1.1186 1.0 1470375 Maybridge3_000095 Clc1cccc(c1Cl)S(=O)(=O)N2CCCN(CC2)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E08 compound treatment 0.329 0.00488 0.39 0.343 0.00767 0.7 0.7697 0.9633 2075220 Maybridge3_000096 OC(COc1ccc(/N=C/c2ccc(Cl)cc2)cc1)CN3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E09 compound treatment 0.316 -0.00812 -0.65 0.332 -0.00333 -0.3 -0.6766 -0.9386 1589430 Maybridge3_000097 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E10 compound treatment 0.328 0.00388 0.31 0.342 0.00667 0.61 0.6485 0.9525 2075221 Maybridge3_000098 FC(F)(F)c1ccnc(Oc2ccc(I)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E11 compound treatment 0.315 -0.00912 -0.73 0.34 0.00467 0.42 -0.2201 -0.2594 1678944 Maybridge3_000099 Clc1ccc(CN2CCCNCC2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E12 compound treatment 0.34 0.0159 1.28 0.348 0.0127 1.15 1.7169 0.9986 2075222 Maybridge3_000100 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)N3CCSCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E13 compound treatment 0.31 -0.0141 -1.14 0.334 -0.00133 -0.12 -0.8899 -0.778 1517901 Maybridge3_000101 OC(COc1ccc(Cl)c(Cl)c1)CN2CCC(O)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E14 compound treatment 0.339 0.0149 1.2 0.342 0.00667 0.61 1.2749 0.95 2075223 Maybridge3_000102 COc1cc(/C=C/2\CCCCC2=O)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E15 compound treatment 0.329 0.00488 0.39 0.337 0.00167 0.15 0.3846 0.9141 2075224 Maybridge3_000103 CCOC(=O)c1cc(/C(=N/O)/N)c(C)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E16 compound treatment 0.332 0.00788 0.63 0.339 0.00367 0.33 0.6838 0.9547 2075225 Maybridge3_000104 CC(=O)Nc1ccc(C)cc1/N=C/c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E17 compound treatment 0.302 -0.0221 -1.78 0.319 -0.0163 -1.48 -2.3082 -0.9958 1127707 Maybridge3_000105 Cc1cc(Cl)cc(Br)c1OCC(O)CNCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E18 compound treatment 0.329 0.00488 0.39 0.339 0.00367 0.33 0.5129 0.9966 2075226 Maybridge3_000106 CCOC(=O)/C(=C(/C)\Nc1ccc(F)cc1)/C2CC(=O)N(C2=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E19 compound treatment 0.328 0.00388 0.31 0.337 0.00167 0.15 0.3276 0.9448 2075227 Maybridge3_000107 COC(=O)c1sccc1Oc2nccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E20 compound treatment 0.349 0.0249 2.0 0.354 0.0187 1.69 2.6145 0.9965 2075228 Maybridge3_000108 Oc1ccc(Br)cc1/C=N/c2ccc3[nH]nnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E21 compound treatment 0.342 0.0179 1.44 0.341 0.00567 0.51 1.3815 0.9038 2075229 Maybridge3_000109 Cc1nc(ccc1C(=O)N2CCCCC2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E22 compound treatment 0.33 0.00588 0.47 0.342 0.00667 0.61 0.7624 0.9926 2075230 Maybridge3_000110 C/C=C(\C)/C(=O)Nc1ccc(cc1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E23 mock treatment 0.319 -0.00512 -0.41 0.329 -0.00633 -0.57 -0.6983 -0.9868 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 E24 positive control 0.088 -0.236 -19.01 0.087 -0.248 -22.54 -29.3844 -0.9964 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F01 compound treatment 0.336 0.0119 0.96 0.341 0.00567 0.51 1.0399 0.9577 1295702 Maybridge3_000111 Cc1cc(C)c(NC(=O)CSCc2cnc(C)c(O)c2CO)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F02 compound treatment 0.333 0.00888 0.71 0.342 0.00667 0.61 0.9333 0.9966 1449189 Maybridge3_000112 Cc1ccccc1C(=O)NCC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F03 compound treatment 0.332 0.00788 0.63 0.341 0.00567 0.51 0.8121 0.9946 2075231 Maybridge3_000113 Cn1ncc(C#N)c1n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F04 compound treatment 0.334 0.00988 0.8 0.339 0.00367 0.33 0.7976 0.9253 2075232 Maybridge3_000114 COc1ccccc1Oc2ccc(cc2N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F05 compound treatment 0.331 0.00688 0.55 0.348 0.0127 1.15 1.2045 0.9439 2075233 Maybridge3_000115 COC(=O)C1SC/C(=N\O)/C1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F06 compound treatment 0.331 0.00688 0.55 0.349 0.0137 1.24 1.2687 0.9339 1209945 Maybridge3_000116 Fc1ccc(cc1Cl)c2nc3cccc(F)c3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F07 compound treatment 0.328 0.00388 0.31 0.339 0.00367 0.33 0.456 0.9995 1422600 Maybridge3_000117 Clc1c(sc2ccccc12)C(=O)NCC3CCC(CC3)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F08 compound treatment 0.335 0.0109 0.88 0.346 0.0107 0.97 1.3039 0.9987 2075234 Maybridge3_000118 Clc1cccc2nc(oc(=O)c12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F09 compound treatment 0.323 -0.00112 -0.09 0.329 -0.00633 -0.57 -0.4706 -0.8086 2075235 Maybridge3_000119 Cc1cc(ccc1Cl)C(=O)CSC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F10 compound treatment 0.342 0.0179 1.44 0.373 0.0377 3.42 3.4355 0.9261 1399737 Maybridge3_000120 CC(=O)Nc1cc2cc(NC(=O)c3c(F)cccc3F)ccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F11 compound treatment 0.327 0.00288 0.23 0.344 0.00867 0.79 0.72 0.878 2075236 Maybridge3_000121 Nc1ccc(c(C#N)c1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F12 compound treatment 0.332 0.00788 0.63 0.335 -3.33E-4 -0.03 0.427 0.6726 2075237 Maybridge3_000122 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3cccc(SC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F13 compound treatment 0.267 -0.0571 -4.6 0.304 -0.0313 -2.84 -5.2639 -0.9733 1012037 Maybridge3_000123 O=C(CCN1CCCCC1)c2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F14 compound treatment 0.332 0.00788 0.63 0.343 0.00767 0.7 0.9405 0.9989 2075238 Maybridge3_000124 CCc1nc2cc(cc(Cl)c2nc1CC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F15 compound treatment 0.34 0.0159 1.28 0.347 0.0117 1.06 1.6528 0.9956 1917196 Maybridge3_000125 FC(F)(F)C(=O)NCCc1ccncc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F16 compound treatment 0.335 0.0109 0.88 0.349 0.0137 1.24 1.4964 0.9855 2075239 Maybridge3_000126 Clc1ccc2OC(Nc2c1)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F17 compound treatment 0.336 0.0119 0.96 0.341 0.00567 0.51 1.0399 0.9577 2075240 Maybridge3_000127 O=C(NCCSC1=NCCN1)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F18 compound treatment 0.343 0.0189 1.52 0.342 0.00667 0.61 1.5027 0.9185 1172488 Maybridge3_000128 O=c1nc([nH]c2ccccc12)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F19 compound treatment 0.334 0.00988 0.8 0.347 0.0117 1.06 1.3111 0.99 1505028 Maybridge3_000129 OC(=O)c1c(F)cccc1NC(=O)COc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F20 compound treatment 0.336 0.0119 0.96 0.344 0.00867 0.79 1.2324 0.9953 1261208 Maybridge3_000130 Cc1ccc(NC(=O)Cc2nn[nH]n2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F21 compound treatment 0.342 0.0179 1.44 0.343 0.00767 0.7 1.5099 0.9444 2075241 Maybridge3_000131 CC(C)c1nnc(NCC(C)(C)C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F22 compound treatment 0.341 0.0169 1.36 0.338 0.00267 0.24 1.132 0.8202 2075242 Maybridge3_000132 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F23 mock treatment 0.322 -0.00212 -0.17 0.335 -3.33E-4 -0.03 -0.1424 -0.8194 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 F24 positive control 0.086 -0.238 -19.18 0.087 -0.248 -22.54 -29.4983 -0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G01 compound treatment 0.329 0.00488 0.39 0.343 0.00767 0.7 0.7697 0.9633 2075243 Maybridge3_000133 Oc1ccc(cc1)n2cncn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G02 compound treatment 0.322 -0.00212 -0.17 0.332 -0.00333 -0.3 -0.3349 -0.9636 1484820 Maybridge3_000134 NCCNc1ncnc2scc(c3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G03 compound treatment 0.322 -0.00212 -0.17 0.333 -0.00233 -0.21 -0.2708 -0.9944 2075244 Maybridge3_000135 c1csc(c1)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G04 compound treatment 0.354 0.0299 2.41 0.362 0.0267 2.42 3.4127 1.0 1368451 Maybridge3_000136 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)CCC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G05 compound treatment 0.315 -0.00912 -0.73 0.324 -0.0113 -1.03 -1.247 -0.9864 2075245 Maybridge3_000137 COc1ccc(CCNCC(O)Cn2ccc3ccccc23)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G06 compound treatment 0.317 -0.00712 -0.57 0.34 0.00467 0.42 -0.1062 -0.1489 1139862 Maybridge3_000138 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)NC4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G07 compound treatment 0.318 -0.00612 -0.49 0.334 -0.00133 -0.12 -0.4343 -0.8552 1263570 Maybridge3_000139 OC(COc1ccc(Cl)c(Cl)c1)CN2CCCN(CC2)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G08 compound treatment 0.33 0.00588 0.47 0.344 0.00867 0.79 0.8908 0.9704 1720104 Maybridge3_000140 CC(O)CNc1ncnc2scc(c3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G09 compound treatment 0.33 0.00588 0.47 0.339 0.00367 0.33 0.5699 0.9852 1618125 Maybridge3_000141 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G10 compound treatment 0.323 -0.00112 -0.09 0.336 6.67E-4 0.06 -0.0213 -0.1952 2075246 Maybridge3_000142 CCCc1cnc(nc1)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G11 compound treatment 0.323 -0.00112 -0.09 0.341 0.00567 0.51 0.2997 0.5737 1463644 Maybridge3_000143 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCC3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G12 compound treatment 0.324 -1.25E-4 -0.01 0.332 -0.00333 -0.3 -0.2211 -0.7302 2075247 Maybridge3_000144 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)NC3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G13 compound treatment 0.33 0.00588 0.47 0.345 0.00967 0.88 0.955 0.958 2075248 Maybridge3_000145 Cc1nc(ccc1NC(=O)/C=C/C(=O)O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G14 compound treatment 0.333 0.00888 0.71 0.344 0.00867 0.79 1.0616 0.9989 2075249 Maybridge3_000146 CC(=O)NS(=O)(=O)c1ccc(/N=C/c2ccccc2O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G15 compound treatment 0.329 0.00488 0.39 0.338 0.00267 0.24 0.4487 0.973 1530311 Maybridge3_000147 COC(=O)c1ccc(nc1C)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G16 compound treatment 0.326 0.00188 0.15 0.34 0.00467 0.42 0.4063 0.9035 1918878 Maybridge3_000148 COc1cc(/C=N/Cc2ccccc2)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G17 compound treatment 0.319 -0.00512 -0.41 0.327 -0.00833 -0.76 -0.8267 -0.9594 1704746 Maybridge3_000149 Cc1ccc(OCC(O)CNCc2ccccc2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G18 compound treatment 0.332 0.00788 0.63 0.341 0.00567 0.51 0.8121 0.9946 2075250 Maybridge3_000150 COc1ccc(/C=N/c2cc(NS(=O)(=O)C)ccc2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G19 compound treatment 0.315 -0.00912 -0.73 0.335 -3.33E-4 -0.03 -0.541 -0.7356 2075251 Maybridge3_000151 OC(CSc1ccccc1)CN2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G20 compound treatment 0.344 0.0199 1.6 0.353 0.0177 1.6 2.2656 1.0 1431187 Maybridge3_000152 Cc1onc(c1C(=O)Nc2ccc(cc2)N3CCOCC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G21 compound treatment 0.313 -0.0111 -0.9 0.324 -0.0113 -1.03 -1.3609 -0.9976 2075252 Maybridge3_000153 OC(COc1ccc(Cl)c(Cl)c1)CN2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G22 compound treatment 0.326 0.00188 0.15 0.332 -0.00333 -0.3 -0.1072 -0.317 2075253 Maybridge3_000154 C/C=C(\C)/C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G23 mock treatment 0.327 0.00288 0.23 0.333 -0.00233 -0.21 0.0139 0.0444 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 G24 positive control 0.089 -0.235 -18.93 0.088 -0.247 -22.45 -29.2633 -0.9964 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H01 compound treatment 0.336 0.0119 0.96 0.345 0.00967 0.88 1.2966 0.9991 2075254 Maybridge3_000155 Cc1ncc(CSCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H02 compound treatment 0.361 0.0369 2.97 0.357 0.0217 1.97 3.4904 0.98 2075255 Maybridge3_000156 Fc1ccccc1c2ncc(o2)c3ccc(Br)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H03 compound treatment 0.331 0.00688 0.55 0.341 0.00567 0.51 0.7552 0.9993 2075256 Maybridge3_000157 CC1ONC(=N1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H04 compound treatment 0.335 0.0109 0.88 0.343 0.00767 0.7 1.1113 0.9935 1588151 Maybridge3_000158 COc1ccc(OC)c(c1)S(=O)(=O)NC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H05 compound treatment 0.331 0.00688 0.55 0.346 0.0107 0.97 1.0761 0.9648 1381483 Maybridge3_000159 Nc1cc(Cl)c(cc1N2CCOCC2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H06 compound treatment 0.328 0.00388 0.31 0.345 0.00967 0.88 0.8411 0.9032 1540229 Maybridge3_000160 CC(C)(C)NC(=O)c1cc2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H07 compound treatment 0.308 -0.0161 -1.3 0.312 -0.0233 -2.12 -2.4158 -0.9724 2075257 Maybridge3_000161 Nc1cc(ccc1Oc2ccc(Cl)cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H08 compound treatment 0.328 0.00388 0.31 0.346 0.0107 0.97 0.9053 0.8899 2075258 Maybridge3_000162 FC(F)(F)c1cccc(c1)c2nc3cccc(Cl)c3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H09 compound treatment 0.333 0.00888 0.71 0.346 0.0107 0.97 1.19 0.9888 2075259 Maybridge3_000163 COc1ccc2ncc(nc2c1)c3ccc(Cl)c(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H10 compound treatment 0.331 0.00688 0.55 0.339 0.00367 0.33 0.6268 0.9704 2075260 Maybridge3_000164 Cc1cccc(/N=C/2\NC(C)(C)C(=C)S2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H11 compound treatment 0.312 -0.0121 -0.98 0.334 -0.00133 -0.12 -0.776 -0.7887 2075261 Maybridge3_000165 COc1cccc(C)c1OC(=O)c2cc(F)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H12 compound treatment 0.331 0.00688 0.55 0.336 6.67E-4 0.06 0.4343 0.7798 2075262 Maybridge3_000166 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3ccc(C)c(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H13 compound treatment 0.334 0.00988 0.8 0.351 0.0157 1.42 1.5679 0.9623 2075263 Maybridge3_000167 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Br)cn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H14 compound treatment 0.332 0.00788 0.63 0.343 0.00767 0.7 0.9405 0.9989 2075264 Maybridge3_000168 COC(=O)c1sc2ccccc2c1OC(=O)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H15 compound treatment 0.324 -1.25E-4 -0.01 0.348 0.0127 1.15 0.8059 0.7009 1591924 Maybridge3_000169 O=C(CSc1ccccc1)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H16 compound treatment 0.331 0.00688 0.55 0.346 0.0107 0.97 1.0761 0.9648 2075265 Maybridge3_000170 Fc1ccc2nc(cnc2c1)c3ccc(Cl)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H17 compound treatment 0.342 0.0179 1.44 0.36 0.0247 2.24 2.601 0.9772 2075266 Maybridge3_000171 Cc1nn(nc1C(=O)Nc2cc(Cl)cc(Cl)c2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H18 compound treatment 0.339 0.0149 1.2 0.337 0.00167 0.15 0.954 0.7901 1188919 Maybridge3_000172 Cc1cc(NS(=O)(=O)c2ccc(C)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H19 compound treatment 0.335 0.0109 0.88 0.35 0.0147 1.33 1.5606 0.9794 2075267 Maybridge3_000173 Fc1cccc2nc(oc(=O)c12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H20 compound treatment 0.337 0.0129 1.04 0.344 0.00867 0.79 1.2894 0.9907 2075268 Maybridge3_000174 COC(=O)CSc1cc(C)c(Cl)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H21 compound treatment 0.34 0.0159 1.28 0.34 0.00467 0.42 1.2035 0.8936 2075269 Maybridge3_000175 COc1ccc(cc1OC)S(=O)(=O)Nc2c(F)cc(F)cc2Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H22 compound treatment 0.333 0.00888 0.71 0.338 0.00267 0.24 0.6765 0.8966 1710792 Maybridge3_000176 COC(=O)c1sccc1OC(=O)c2cc3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H23 mock treatment 0.329 0.00488 0.39 0.336 6.67E-4 0.06 0.3204 0.8066 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 H24 positive control 0.091 -0.233 -18.77 0.089 -0.246 -22.36 -29.0853 -0.9962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I01 compound treatment 0.336 0.0119 0.96 0.346 0.0107 0.97 1.3608 1.0 1055531 Maybridge3_000177 OCc1c(F)c(F)c(F)c(F)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I02 compound treatment 0.329 0.00488 0.39 0.339 0.00367 0.33 0.5129 0.9966 1169015 Maybridge3_000178 O=C(N1CCCN(Cc2cccc3ccccc23)CC1)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I03 compound treatment 0.337 0.0129 1.04 0.35 0.0147 1.33 1.6745 0.9924 2075270 Maybridge3_000179 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)n3nccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I04 compound treatment 0.328 0.00388 0.31 0.338 0.00267 0.24 0.3918 0.9921 2075271 Maybridge3_000180 O=C(NCCNc1ncnc2scc(c3ccccc3)c12)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I05 compound treatment 0.332 0.00788 0.63 0.343 0.00767 0.7 0.9405 0.9989 1317957 Maybridge3_000181 COc1ccc(Cc2noc(N)n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I06 compound treatment 0.331 0.00688 0.55 0.341 0.00567 0.51 0.7552 0.9993 1185792 Maybridge3_000182 CC(C)(C)NS(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I07 compound treatment 0.344 0.0199 1.6 0.356 0.0207 1.88 2.4582 0.9969 2075272 Maybridge3_000183 OC(COc1ccc(OC(F)(F)F)cc1)CS(=O)(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I08 compound treatment 0.329 0.00488 0.39 0.346 0.0107 0.97 0.9622 0.921 1465029 Maybridge3_000184 Cc1ccc(cc1)c2csc3ncnc(N4CCNCC4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I09 compound treatment 0.326 0.00188 0.15 0.353 0.0177 1.6 1.2407 0.7703 1557263 Maybridge3_000185 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I10 compound treatment 0.339 0.0149 1.2 0.352 0.0167 1.51 1.9167 0.9933 2075273 Maybridge3_000186 Oc1ncnc2scc(c3ccc4ccccc4c3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I11 compound treatment 0.336 0.0119 0.96 0.348 0.0127 1.15 1.4892 0.9958 2075274 Maybridge3_000187 CC(C)c1csc2nc[nH]c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I12 compound treatment 0.339 0.0149 1.2 0.355 0.0197 1.79 2.1093 0.9812 2075275 Maybridge3_000188 CC(O)C/N=C(\C)/c1cc(Cl)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I13 compound treatment 0.331 0.00688 0.55 0.352 0.0167 1.51 1.4612 0.907 2075276 Maybridge3_000189 NC(=O)c1ccc([nH]c1=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I14 compound treatment 0.331 0.00688 0.55 0.348 0.0127 1.15 1.2045 0.9439 1310718 Maybridge3_000190 Clc1c(sc2ccccc12)C(=O)N(CCC#N)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I15 compound treatment 0.335 0.0109 0.88 0.342 0.00667 0.61 1.0471 0.9837 1523218 Maybridge3_000191 CCOC(=O)c1cc(C#N)c(C)nc1NCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I16 compound treatment 0.333 0.00888 0.71 0.339 0.00367 0.33 0.7407 0.9395 2075277 Maybridge3_000192 COc1cccc(/C=N/c2ccccc2C(=O)Nc3ccc(F)cc3)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I17 compound treatment 0.325 8.75E-4 0.07 0.346 0.0107 0.97 0.7345 0.7566 1376595 Maybridge3_000193 Cc1ccc(OCC(O)CNCc2ccco2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I18 compound treatment 0.335 0.0109 0.88 0.344 0.00867 0.79 1.1755 0.9986 2075278 Maybridge3_000194 CCOC(=O)/C(=C(/C)\N)/C1CC(=O)N(C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I19 compound treatment 0.334 0.00988 0.8 0.344 0.00867 0.79 1.1186 1.0 2075279 Maybridge3_000195 C(Oc1cccnc1)C2=NCCN2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I20 compound treatment 0.343 0.0189 1.52 0.348 0.0127 1.15 1.8878 0.9905 1152459 Maybridge3_000196 CC(=O)Nc1ccc(NC(=O)c2cccc(Cl)c2)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I21 compound treatment 0.34 0.0159 1.28 0.35 0.0147 1.33 1.8453 0.9998 2075280 Maybridge3_000197 FC(F)(F)c1ccnc(Sc2ccccc2NC(=O)CSc3ccccn3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I22 compound treatment 0.346 0.0219 1.76 0.346 0.0107 0.97 1.9302 0.9603 1061675 Maybridge3_000198 CNc1ccc(Cl)cc1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I23 mock treatment 0.328 0.00388 0.31 0.341 0.00567 0.51 0.5844 0.9713 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 I24 positive control 0.089 -0.235 -18.93 0.09 -0.245 -22.27 -29.135 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J01 compound treatment 0.336 0.0119 0.96 0.345 0.00967 0.88 1.2966 0.9991 1327006 Maybridge3_000199 COc1ccccc1NC(=O)CSCc2cnc(C)c(O)c2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J02 compound treatment 0.341 0.0169 1.36 0.35 0.0147 1.33 1.9023 0.9999 2075281 Maybridge3_000200 Fc1ccccc1c2ncc(o2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J03 compound treatment 0.331 0.00688 0.55 0.337 0.00167 0.15 0.4984 0.8685 2075282 Maybridge3_000201 Fc1ccc(NC(=O)CCc2nc(no2)c3ccc(Cl)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J04 compound treatment 0.333 0.00888 0.71 0.342 0.00667 0.61 0.9333 0.9966 2075283 Maybridge3_000202 Clc1cc(Cl)cc(c1)C(=O)NC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J05 compound treatment 0.314 -0.0101 -0.82 0.334 -0.00133 -0.12 -0.6621 -0.8033 1160752 Maybridge3_000203 Clc1ccc(cc1)c2csc(=N)n2c3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J06 compound treatment 0.335 0.0109 0.88 0.346 0.0107 0.97 1.3039 0.9987 1382622 Maybridge3_000204 O=C(NC1CC1)c2cc3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J07 compound treatment 0.325 8.75E-4 0.07 0.344 0.00867 0.79 0.6061 0.7674 1163772 Maybridge3_000205 CS(=O)(=O)N(c1cccc(C#N)c1)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J08 compound treatment 0.33 0.00588 0.47 0.345 0.00967 0.88 0.955 0.958 2075284 Maybridge3_000206 Fc1cc(Br)c(c(Br)c1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J09 compound treatment 0.334 0.00988 0.8 0.348 0.0127 1.15 1.3753 0.9838 1391249 Maybridge3_000207 Nc1nc(nc2n(ncc12)c3ccccc3)c4ccncc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J10 compound treatment 0.323 -0.00112 -0.09 0.336 6.67E-4 0.06 -0.0213 -0.1952 1664843 Maybridge3_000208 Nc1ccc(Cl)cc1C(=O)NCCc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J11 compound treatment 0.333 0.00888 0.71 0.346 0.0107 0.97 1.19 0.9888 1510127 Maybridge3_000209 CCOC(=O)c1cc(OC)ccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J12 compound treatment 0.349 0.0249 2.0 0.349 0.0137 1.24 2.2936 0.9735 1404519 Maybridge3_000210 Cc1cc(Oc2c(C)cccc2C)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J13 compound treatment 0.318 -0.00612 -0.49 0.334 -0.00133 -0.12 -0.4343 -0.8552 1397748 Maybridge3_000211 OC(CCN1CCCCC1)c2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J14 compound treatment 0.327 0.00288 0.23 0.336 6.67E-4 0.06 0.2065 0.8629 2075285 Maybridge3_000212 COC(=O)c1sc2ccccc2c1OC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J15 compound treatment 0.32 -0.00412 -0.33 0.344 0.00867 0.79 0.3214 0.3764 1205036 Maybridge3_000213 Cc1ccc(SCC(=O)NCc2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J16 compound treatment 0.346 0.0219 1.76 0.356 0.0207 1.88 2.5721 0.9995 1714158 Maybridge3_000214 COc1cc2c(=O)oc(nc2c(OC)c1OC)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J17 compound treatment 0.331 0.00688 0.55 0.344 0.00867 0.79 0.9477 0.9852 2075286 Maybridge3_000215 CSCc1ccc(cc1)C(=O)Nc2ccc(C)cc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J18 compound treatment 0.333 0.00888 0.71 0.337 0.00167 0.15 0.6123 0.8382 2075287 Maybridge3_000216 CCOC(=O)c1cc2cc(Cl)ccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J19 compound treatment 0.342 0.0179 1.44 0.344 0.00867 0.79 1.5741 0.9596 1164150 Maybridge3_000217 Fc1cccc(NC(=O)c2cccs2)c1C(=O)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J20 compound treatment 0.34 0.0159 1.28 0.344 0.00867 0.79 1.4602 0.9728 1536952 Maybridge3_000218 O=C(NCC1CC1)c2cc3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J21 compound treatment 0.34 0.0159 1.28 0.343 0.00767 0.7 1.396 0.9591 2075288 Maybridge3_000219 Fc1cc(F)c(NC(=O)c2cccs2)c(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J22 compound treatment 0.34 0.0159 1.28 0.339 0.00367 0.33 1.1393 0.8625 2075289 Maybridge3_000220 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J23 mock treatment 0.325 8.75E-4 0.07 0.336 6.67E-4 0.06 0.0926 0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 J24 positive control 0.091 -0.233 -18.77 0.091 -0.244 -22.18 -28.9569 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K01 compound treatment 0.334 0.00988 0.8 0.346 0.0107 0.97 1.2469 0.9952 2042 Maybridge3_000221 CN(C)c1ncnc2[nH]cnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K02 compound treatment 0.337 0.0129 1.04 0.349 0.0137 1.24 1.6103 0.996 1367399 Maybridge3_000222 OC(=O)C1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K03 compound treatment 0.33 0.00588 0.47 0.339 0.00367 0.33 0.5699 0.9852 2075290 Maybridge3_000223 OC(=O)/C=C/C(=O)Nc1ccc(cc1)n2nccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K04 compound treatment 0.337 0.0129 1.04 0.345 0.00967 0.88 1.3536 0.9966 2075291 Maybridge3_000224 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K05 compound treatment 0.354 0.0299 2.41 0.372 0.0367 3.33 4.0546 0.9873 1276407 Maybridge3_000225 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc(s2)c3csc(C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K06 compound treatment 0.329 0.00488 0.39 0.342 0.00667 0.61 0.7055 0.978 1564123 Maybridge3_000226 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)NCC4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K07 compound treatment 0.348 0.0239 1.92 0.36 0.0247 2.24 2.9427 0.9971 1142977 Maybridge3_000227 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K08 compound treatment 0.348 0.0239 1.92 0.341 0.00567 0.51 1.7232 0.8658 1445458 Maybridge3_000228 CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K09 compound treatment 0.328 0.00388 0.31 0.336 6.67E-4 0.06 0.2634 0.8288 1611715 Maybridge3_000229 CC(C)(C)OC(=O)NCCN1C(=O)CC2(CCCC2)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K10 compound treatment 0.333 0.00888 0.71 0.341 0.00567 0.51 0.8691 0.987 1158858 Maybridge3_000230 CCCc1cnc(nc1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K11 compound treatment 0.351 0.0269 2.16 0.365 0.0297 2.69 3.4344 0.9941 1576456 Maybridge3_000231 OC(CSc1ccc(F)cc1)CN2CCN(CC2)c3nc4ccc(Cl)cc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K12 compound treatment 0.327 0.00288 0.23 0.342 0.00667 0.61 0.5916 0.9131 2075292 Maybridge3_000232 COC(=O)c1ccc(CSc2ccccc2N)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K13 compound treatment 0.342 0.0179 1.44 0.346 0.0107 0.97 1.7025 0.9814 2075293 Maybridge3_000233 Cc1cn(nc1C(F)(F)F)c2ncnc3scc(c4ccccc4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K14 compound treatment 0.325 8.75E-4 0.07 0.338 0.00267 0.24 0.221 0.8766 2075294 Maybridge3_000234 Cc1cccc(C)c1/N=C/2\NC3(CCCCC3)C(=C)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K15 compound treatment 0.328 0.00388 0.31 0.34 0.00467 0.42 0.5202 0.9887 2075295 Maybridge3_000235 Cc1nc(ccc1C(=O)Oc2ccc(F)cc2F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K16 compound treatment 0.352 0.0279 2.24 0.354 0.0187 1.69 2.7853 0.9904 2075296 Maybridge3_000236 COc1cc(N2C(SCC2=O)c3ccccc3)c(OC)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K17 compound treatment 0.332 0.00788 0.63 0.344 0.00867 0.79 1.0047 0.9943 2075297 Maybridge3_000237 FC(F)(F)c1cccnc1N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K18 compound treatment 0.332 0.00788 0.63 0.348 0.0127 1.15 1.2614 0.9607 1515242 Maybridge3_000238 CCOC(=O)C1=C(C)NC(=O)C1CC(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K19 compound treatment 0.335 0.0109 0.88 0.354 0.0187 1.69 1.8174 0.9528 2075298 Maybridge3_000239 Cc1oc(cc1C(=O)NCCNc2nccc(n2)C(F)(F)F)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K20 compound treatment 0.323 -0.00112 -0.09 0.333 -0.00233 -0.21 -0.2138 -0.9282 1249782 Maybridge3_000240 Clc1cccc(c1)C(=O)Nc2ccc3[nH]nnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K21 compound treatment 0.347 0.0229 1.84 0.352 0.0167 1.51 2.3723 0.9952 1077231 Maybridge3_000241 CCOC(=O)C(=C1CCN(Cc2ccccc2)CC1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K22 compound treatment 0.338 0.0139 1.12 0.337 0.00167 0.15 0.897 0.7956 1538537 Maybridge3_000242 NC(=O)c1ccccc1NCC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K23 mock treatment 0.324 -1.25E-4 -0.01 0.334 -0.00133 -0.12 -0.0927 -0.7633 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 K24 positive control 0.091 -0.233 -18.77 0.092 -0.243 -22.09 -28.8927 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L01 compound treatment 0.339 0.0149 1.2 0.348 0.0127 1.15 1.66 0.9998 2075299 Maybridge3_000243 Cc1ncc(CSCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L02 compound treatment 0.334 0.00988 0.8 0.346 0.0107 0.97 1.2469 0.9952 1333099 Maybridge3_000244 O=C(N1CCOCC1)c2cc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L03 compound treatment 0.343 0.0189 1.52 0.347 0.0117 1.06 1.8236 0.9844 1117699 Maybridge3_000245 Fc1ccc(NC(=O)c2ccccc2NC(=O)c3ccco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L04 compound treatment 0.326 0.00188 0.15 0.334 -0.00133 -0.12 0.0212 0.1095 2075300 Maybridge3_000246 CCC1(CC)N/C(=N/c2ccc(F)c(Cl)c2)/SC1=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L05 compound treatment 0.329 0.00488 0.39 0.344 0.00867 0.79 0.8339 0.9484 2075301 Maybridge3_000247 CC(C)(C)n1ncc(C#N)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L06 compound treatment 0.335 0.0109 0.88 0.347 0.0117 1.06 1.3681 0.9955 1495296 Maybridge3_000248 O=C(N1CCCCC1)c2cc3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L07 compound treatment 0.332 0.00788 0.63 0.346 0.0107 0.97 1.133 0.9789 2075302 Maybridge3_000249 N/C(=N\O)/c1cccc(c1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L08 compound treatment 0.326 0.00188 0.15 0.344 0.00867 0.79 0.663 0.8277 2075303 Maybridge3_000250 Nc1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L09 compound treatment 0.335 0.0109 0.88 0.365 0.0297 2.69 2.5234 0.8911 1195614 Maybridge3_000251 CC(C)(C)CC(C)(C)NC(=O)c1cccnc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L10 compound treatment 0.334 0.00988 0.8 0.341 0.00567 0.51 0.926 0.9778 1642557 Maybridge3_000252 Clc1ccc(CCNC(=O)c2cc3ccccc3oc2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L11 compound treatment 0.338 0.0139 1.12 0.344 0.00867 0.79 1.3463 0.9853 2075304 Maybridge3_000253 OC(=O)CCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L12 compound treatment 0.336 0.0119 0.96 0.344 0.00867 0.79 1.2324 0.9953 1251326 Maybridge3_000254 COC(=O)c1ccc(Cl)cc1NC(=O)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L13 compound treatment 0.328 0.00388 0.31 0.34 0.00467 0.42 0.5202 0.9887 1348369 Maybridge3_000255 Clc1ccccc1C(=O)Nc2ccccc2C(=O)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L14 compound treatment 0.338 0.0139 1.12 0.341 0.00567 0.51 1.1538 0.938 2075305 Maybridge3_000256 CSc1ncc(C#N)c2nc(nn12)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L15 compound treatment 0.346 0.0219 1.76 0.354 0.0187 1.69 2.4437 0.9998 2075306 Maybridge3_000257 O=C(NCCSc1ccccc1)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L16 compound treatment 0.335 0.0109 0.88 0.343 0.00767 0.7 1.1113 0.9935 1641688 Maybridge3_000258 Cn1c(nc(=O)c2cc(Cl)ccc12)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L17 compound treatment 0.341 0.0169 1.36 0.351 0.0157 1.42 1.9664 0.9997 2075307 Maybridge3_000259 CC1CN(CC(C)O1)C(C#N)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L18 compound treatment 0.339 0.0149 1.2 0.349 0.0137 1.24 1.7242 0.9998 1370020 Maybridge3_000260 CCOC(=O)c1cc(NC(=O)c2cc3ccccc3oc2=O)sc1CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L19 compound treatment 0.344 0.0199 1.6 0.353 0.0177 1.6 2.2656 1.0 2075308 Maybridge3_000261 Fc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1C(=O)NCCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L20 compound treatment 0.335 0.0109 0.88 0.345 0.00967 0.88 1.2397 1.0 1352714 Maybridge3_000262 Cc1nn(nc1C(=O)NCC2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L21 compound treatment 0.438 0.114 9.17 0.44 0.105 9.5 13.2022 0.9998 2075309 Maybridge3_000263 COC(C/N=C/c1cc(Cl)cc(Cl)c1O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L22 compound treatment 0.25 -0.0741 -5.97 0.277 -0.0583 -5.29 -7.9649 -0.9982 2075310 Maybridge3_000264 C/C(=C\C(=O)Nc1ccc(F)cc1)/Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L23 mock treatment 0.333 0.00888 0.71 0.339 0.00367 0.33 0.7407 0.9395 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 L24 positive control 0.092 -0.232 -18.69 0.094 -0.241 -21.91 -28.7074 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M01 compound treatment 0.331 0.00688 0.55 0.341 0.00567 0.51 0.7552 0.9993 2075311 Maybridge3_000265 C(=N/c1cccc2ccccc12)/c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M02 compound treatment 0.326 0.00188 0.15 0.335 -3.33E-4 -0.03 0.0854 0.5544 2075312 Maybridge3_000266 CC(C)Nc1nccc(n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M03 compound treatment 0.326 0.00188 0.15 0.329 -0.00633 -0.57 -0.2997 -0.5043 2075313 Maybridge3_000267 FC(F)(F)c1ccnc(NCc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M04 compound treatment 0.325 8.75E-4 0.07 0.331 -0.00433 -0.39 -0.2283 -0.5713 1310185 Maybridge3_000268 OC(CN1CCN(Cc2c(F)cccc2Cl)CC1)Cn3ccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M05 compound treatment 0.323 -0.00112 -0.09 0.338 0.00267 0.24 0.1071 0.4144 1049274 Maybridge3_000269 OC(=O)CC1(CCCC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M06 compound treatment 0.338 0.0139 1.12 0.354 0.0187 1.69 1.9882 0.9796 2075314 Maybridge3_000270 C(Nc1ncnc2scc(c3ccccc3)c12)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M07 compound treatment 0.339 0.0149 1.2 0.347 0.0117 1.06 1.5958 0.9981 1323196 Maybridge3_000271 Cc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M08 compound treatment 0.338 0.0139 1.12 0.345 0.00967 0.88 1.4105 0.9928 2075315 Maybridge3_000272 COc1cccc(CC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M09 compound treatment 0.331 0.00688 0.55 0.336 6.67E-4 0.06 0.4343 0.7798 2075316 Maybridge3_000273 CC(C)(C)OC(=O)N1CCC(O)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M10 compound treatment 0.304 -0.0201 -1.62 0.319 -0.0163 -1.48 -2.1943 -0.999 2075317 Maybridge3_000274 Fc1cccc(Cl)c1CN2CCN(CCCNc3nc(ns3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M11 compound treatment 0.356 0.0319 2.57 0.351 0.0157 1.42 2.8206 0.9612 1572373 Maybridge3_000275 OC(CN1CCCC1=O)CN2CCN(CC2)c3nc4ccc(Cl)cc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M12 compound treatment 0.327 0.00288 0.23 0.337 0.00167 0.15 0.2707 0.9787 2075318 Maybridge3_000276 O=C(NC1=NCCS1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M13 compound treatment 0.322 -0.00212 -0.17 0.338 0.00267 0.24 0.0502 0.1692 2075319 Maybridge3_000277 Cc1c[nH]nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M14 compound treatment 0.331 0.00688 0.55 0.334 -0.00133 -0.12 0.3059 0.5398 1715499 Maybridge3_000278 COc1ccc(NC(=O)C)c(NC(=O)c2ccc(Cl)cc2Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M15 compound treatment 0.324 -1.25E-4 -0.01 0.337 0.00167 0.15 0.0999 0.6586 2075320 Maybridge3_000279 Cc1nc(ccc1C(=O)Sc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M16 compound treatment 0.393 0.0689 5.55 0.411 0.0757 6.87 8.7785 0.9944 2075321 Maybridge3_000280 CCOC(=O)c1cc(C)ccc1/N=C/c2cc(Cl)cc(Cl)c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M17 compound treatment 0.329 0.00488 0.39 0.334 -0.00133 -0.12 0.192 0.4674 2075322 Maybridge3_000281 FC(F)(F)c1ccn(n1)c2ncnc3scc(c4ccccc4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M18 compound treatment 0.326 0.00188 0.15 0.333 -0.00233 -0.21 -0.043 -0.1653 1397179 Maybridge3_000282 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M19 compound treatment 0.335 0.0109 0.88 0.34 0.00467 0.42 0.9188 0.9445 2075323 Maybridge3_000283 Cc1nc(ccc1C(=O)NCCNc2ncccc2C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M20 compound treatment 0.326 0.00188 0.15 0.335 -3.33E-4 -0.03 0.0854 0.5544 2075324 Maybridge3_000284 CCc1cc(CC)c(NC(=O)C(C)(C)C)c(CC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M21 compound treatment 0.325 8.75E-4 0.07 0.328 -0.00733 -0.67 -0.4209 -0.6287 1523751 Maybridge3_000285 C(N1CCCNCC1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M22 compound treatment 0.337 0.0129 1.04 0.338 0.00267 0.24 0.9043 0.8494 2075325 Maybridge3_000286 Oc1ccccc1/C=N/c2cc(ccc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M23 mock treatment 0.32 -0.00412 -0.33 0.332 -0.00333 -0.3 -0.4488 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 M24 positive control 0.091 -0.233 -18.77 0.094 -0.241 -21.91 -28.7643 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N01 compound treatment 0.338 0.0139 1.12 0.344 0.00867 0.79 1.3463 0.9853 2075326 Maybridge3_000287 COc1cccc(OC)c1C(=O)Nc2nnc(s2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N02 compound treatment 0.329 0.00488 0.39 0.34 0.00467 0.42 0.5771 0.9993 2075327 Maybridge3_000288 CC1CCN(CC1)C(=O)c2cc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N03 compound treatment 0.331 0.00688 0.55 0.343 0.00767 0.7 0.8836 0.9936 2075328 Maybridge3_000289 Brc1cc(Br)c2nc(oc(=O)c2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N04 compound treatment 0.333 0.00888 0.71 0.339 0.00367 0.33 0.7407 0.9395 2075329 Maybridge3_000290 CCOC(=O)c1cnc(SCC(=O)c2ccc(Cl)c(C)c2)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N05 compound treatment 0.324 -1.25E-4 -0.01 0.334 -0.00133 -0.12 -0.0927 -0.7633 2075330 Maybridge3_000291 FC(F)(F)c1ccc(N2CCOCC2)c(c1)n3c(csc3=N)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N06 compound treatment 0.337 0.0129 1.04 0.348 0.0127 1.15 1.5461 0.9987 1320006 Maybridge3_000292 O=C(Nc1ccccc1N2CCOCC2)c3cc4ccccc4oc3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N07 compound treatment 0.333 0.00888 0.71 0.336 6.67E-4 0.06 0.5481 0.7642 1478773 Maybridge3_000293 Cc1cccc(C)c1NC(=O)CSC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N08 compound treatment 0.338 0.0139 1.12 0.341 0.00567 0.51 1.1538 0.938 1436586 Maybridge3_000294 COC(=O)C=c1sc2nc3ccccc3n2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N09 compound treatment 0.347 0.0229 1.84 0.346 0.0107 0.97 1.9872 0.9549 1547277 Maybridge3_000295 O=C(N1CCOCC1)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N10 compound treatment 0.358 0.0339 2.73 0.359 0.0237 2.15 3.4479 0.993 2075331 Maybridge3_000296 Clc1ccc(CCNC(=O)c2cccnc2Oc3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N11 compound treatment 0.338 0.0139 1.12 0.342 0.00667 0.61 1.218 0.9585 2075332 Maybridge3_000297 N#CCCn1ncc(C#N)c1n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N12 compound treatment 0.33 0.00588 0.47 0.342 0.00667 0.61 0.7624 0.9926 1620514 Maybridge3_000298 COC(=O)c1ccc(Cl)cc1NC(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N13 compound treatment 0.361 0.0369 2.97 0.365 0.0297 2.69 4.0039 0.9988 2075333 Maybridge3_000299 Nc1ccccc1c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N14 compound treatment 0.339 0.0149 1.2 0.341 0.00567 0.51 1.2107 0.9287 1246890 Maybridge3_000300 Cc1ccc(NC(=O)Cc2ncon2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N15 compound treatment 0.333 0.00888 0.71 0.337 0.00167 0.15 0.6123 0.8382 2075334 Maybridge3_000301 FC(F)(F)C(=O)Nc1ccccc1c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N16 compound treatment 0.338 0.0139 1.12 0.349 0.0137 1.24 1.6673 0.9986 2075335 Maybridge3_000302 CC1CN(CC(=N)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)CC(C)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N17 compound treatment 0.334 0.00988 0.8 0.347 0.0117 1.06 1.3111 0.99 2075336 Maybridge3_000303 Cc1nn(nc1C(=O)Oc2ccc(Cl)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N18 compound treatment 0.337 0.0129 1.04 0.344 0.00867 0.79 1.2894 0.9907 1735808 Maybridge3_000304 CCOC(=O)c1cc(CC)sc1NC(=O)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N19 compound treatment 0.342 0.0179 1.44 0.343 0.00767 0.7 1.5099 0.9444 2075337 Maybridge3_000305 CCOC(=O)c1c[nH]c2c(F)cc(F)cc2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N20 compound treatment 0.335 0.0109 0.88 0.34 0.00467 0.42 0.9188 0.9445 2075338 Maybridge3_000306 O=C(NCC1CC1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N21 compound treatment 0.351 0.0269 2.16 0.362 0.0267 2.42 3.2419 0.9984 1512174 Maybridge3_000307 Cc1cc(C)c(NC(=O)CSCC(=O)c2ccc(Cl)cc2)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N22 compound treatment 0.347 0.0229 1.84 0.344 0.00867 0.79 1.8588 0.928 2075339 Maybridge3_000308 Cc1cc(no1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N23 mock treatment 0.325 8.75E-4 0.07 0.336 6.67E-4 0.06 0.0926 0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 N24 positive control 0.091 -0.233 -18.77 0.093 -0.242 -22.0 -28.8285 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O01 compound treatment 0.343 0.0189 1.52 0.353 0.0177 1.6 2.2087 0.9996 2075340 Maybridge3_000309 CCOc1nc(N)nc(NC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O02 compound treatment 0.333 0.00888 0.71 0.346 0.0107 0.97 1.19 0.9888 2075341 Maybridge3_000310 FC(F)(F)c1ccnc(NCc2ccc3OCOc3c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O03 compound treatment 0.355 0.0309 2.49 0.364 0.0287 2.6 3.598 0.9997 2075342 Maybridge3_000311 Nc1ccccc1Sc2ncnc3scc(c4ccccc4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O04 compound treatment 0.341 0.0169 1.36 0.348 0.0127 1.15 1.7739 0.9965 2075343 Maybridge3_000312 OC(=O)/C=C/C(=O)N1CCCN(CC1)c2ncccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O05 compound treatment 0.34 0.0159 1.28 0.351 0.0157 1.42 1.9095 0.9986 2075344 Maybridge3_000313 OC(CSc1ccccc1)CN2CCN(CC2)c3nccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O06 compound treatment 0.331 0.00688 0.55 0.342 0.00667 0.61 0.8194 0.999 2075345 Maybridge3_000314 NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O07 compound treatment 0.35 0.0259 2.08 0.351 0.0157 1.42 2.4789 0.9827 1468130 Maybridge3_000315 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O08 compound treatment 0.337 0.0129 1.04 0.347 0.0117 1.06 1.4819 0.9999 2075346 Maybridge3_000316 Cc1nc(ccc1NC(=O)C(F)(F)Sc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O09 compound treatment 0.342 0.0179 1.44 0.347 0.0117 1.06 1.7666 0.9886 2075347 Maybridge3_000317 Cc1nc(ccc1c2nnc(SC(=O)c3ccc(Cl)cc3)o2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O10 compound treatment 0.326 0.00188 0.15 0.339 0.00367 0.33 0.3421 0.9361 2075348 Maybridge3_000318 O=C(NCCCN1CCN(Cc2ccccc2)CC1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O11 compound treatment 0.344 0.0199 1.6 0.348 0.0127 1.15 1.9447 0.9868 1676831 Maybridge3_000319 OC(CN1CCN(CC1)c2nc3ccc(Cl)cc3s2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O12 compound treatment 0.34 0.0159 1.28 0.345 0.00967 0.88 1.5244 0.9831 2075349 Maybridge3_000320 O=C(NC1=NCCS1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O13 compound treatment 0.34 0.0159 1.28 0.34 0.00467 0.42 1.2035 0.8936 2075350 Maybridge3_000321 Cc1nc(ccc1NC(=O)c2ccc(cc2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O14 compound treatment 0.346 0.0219 1.76 0.344 0.00867 0.79 1.8019 0.934 1366003 Maybridge3_000322 COc1nc(Nc2ccc(F)cc2)nc(OC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O15 compound treatment 0.341 0.0169 1.36 0.35 0.0147 1.33 1.9023 0.9999 2075351 Maybridge3_000323 FC(F)(F)c1ccnc(NCCNC(=O)C2CC2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O16 compound treatment 0.341 0.0169 1.36 0.347 0.0117 1.06 1.7097 0.9924 1016138 Maybridge3_000324 OC(=O)CSC1(CCCCC1)SCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O17 compound treatment 0.345 0.0209 1.68 0.347 0.0117 1.06 1.9375 0.9752 2075352 Maybridge3_000325 FC(F)(F)c1ccn(n1)c2nc(ns2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O18 compound treatment 0.367 0.0429 3.45 0.363 0.0277 2.51 4.2171 0.9878 1123304 Maybridge3_000326 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O19 compound treatment 0.342 0.0179 1.44 0.344 0.00867 0.79 1.5741 0.9596 2075353 Maybridge3_000327 Clc1ccc(cc1)S(=O)(=O)N2CCN=C2COc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O20 compound treatment 0.339 0.0149 1.2 0.345 0.00967 0.88 1.4675 0.9883 1029792 Maybridge3_000328 C(CN1CCCCC1)C2CCCCN2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O21 compound treatment 0.346 0.0219 1.76 0.355 0.0197 1.79 2.5079 1.0 2075354 Maybridge3_000329 OC(=O)c1ccccc1C(=O)N2CCCN(CC2)c3ncccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O22 compound treatment 0.347 0.0229 1.84 0.351 0.0157 1.42 2.3081 0.9918 1537726 Maybridge3_000330 O=C(Nc1ccc2OCOCc2c1)c3cc4ccccc4oc3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O23 mock treatment 0.33 0.00588 0.47 0.342 0.00667 0.61 0.7624 0.9926 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 O24 positive control 0.092 -0.232 -18.69 0.092 -0.243 -22.09 -28.8358 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P01 compound treatment 0.338 0.0139 1.12 0.346 0.0107 0.97 1.4747 0.9975 2075355 Maybridge3_000331 CCOC(=O)CCc1ccc2OC(Nc2c1)c3ccc(cc3)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P02 compound treatment 0.338 0.0139 1.12 0.342 0.00667 0.61 1.218 0.9585 2075356 Maybridge3_000332 Cc1ccc(NC(=O)Oc2ccc(F)cc2Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P03 compound treatment 0.34 0.0159 1.28 0.336 6.67E-4 0.06 0.9467 0.7398 1270266 Maybridge3_000333 Brc1cc(Br)c2nc(oc(=O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P04 compound treatment 0.335 0.0109 0.88 0.336 6.67E-4 0.06 0.662 0.7542 2075357 Maybridge3_000334 CCOC(=O)c1cnc(SCC(=O)c2ccc(cc2)c3ccccc3)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P05 compound treatment 0.331 0.00688 0.55 0.341 0.00567 0.51 0.7552 0.9993 2075358 Maybridge3_000335 C/C=C(\C)/C(=O)Nc1nncs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P06 compound treatment 0.325 8.75E-4 0.07 0.337 0.00167 0.15 0.1568 0.9395 2075359 Maybridge3_000336 CCC1(CC)N/C(=N/c2ccc(C)cc2C)/SC1=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P07 compound treatment 0.335 0.0109 0.88 0.33 -0.00533 -0.48 0.2769 0.2767 1310840 Maybridge3_000337 OC(=O)c1cnc2c(F)cccc2c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P08 compound treatment 0.386 0.0619 4.98 0.376 0.0407 3.69 6.1334 0.9891 2075360 Maybridge3_000338 COC(=O)/C=C/1\S/C(=N\c2ccc(Cl)cc2)/N(C1=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P09 compound treatment 0.328 0.00388 0.31 0.337 0.00167 0.15 0.3276 0.9448 2075361 Maybridge3_000339 O=C(Sc1ccccc1)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P10 compound treatment 0.355 0.0309 2.49 0.357 0.0217 1.97 3.1487 0.9933 1600278 Maybridge3_000340 CC(=O)Nc1cc2cc(ccc2oc1=O)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P11 compound treatment 0.344 0.0199 1.6 0.351 0.0157 1.42 2.1373 0.9983 1726788 Maybridge3_000341 CC(=O)Nc1cc2cc(N)ccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P12 compound treatment 0.333 0.00888 0.71 0.335 -3.33E-4 -0.03 0.484 0.6766 1372903 Maybridge3_000342 Cc1onc(c1C(=O)Nc2nnc(s2)C3CC3)c4c(F)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P13 compound treatment 0.349 0.0249 2.0 0.354 0.0187 1.69 2.6145 0.9965 2075362 Maybridge3_000343 CN(C)c1ccc(CC(C#N)C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P14 compound treatment 0.333 0.00888 0.71 0.341 0.00567 0.51 0.8691 0.987 1525163 Maybridge3_000344 Clc1cc(Cl)cc(NC(=O)Cc2ncon2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P15 compound treatment 0.338 0.0139 1.12 0.339 0.00367 0.33 1.0254 0.8795 1394189 Maybridge3_000345 Cc1onc(c1C(=O)NCCS(=O)(=O)c2ccccc2)c3c(Cl)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P16 compound treatment 0.329 0.00488 0.39 0.338 0.00267 0.24 0.4487 0.973 2075363 Maybridge3_000346 Clc1cc(Cl)cc(c1)S(=O)(=O)NC(=N)CN2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P17 compound treatment 0.28 -0.0441 -3.55 0.289 -0.0463 -4.21 -5.4864 -0.9965 2075364 Maybridge3_000347 Cc1nn(nc1C(=O)Sc2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P18 compound treatment 0.415 0.0909 7.32 0.403 0.0677 6.14 9.5177 0.9962 1025104 Maybridge3_000348 CSC(=S)Nc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P19 compound treatment 0.363 0.0389 3.13 0.358 0.0227 2.06 3.6684 0.9793 1192638 Maybridge3_000349 CCOC(=O)c1cnc2c(F)cc(F)cc2c1N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P20 compound treatment 0.336 0.0119 0.96 0.337 0.00167 0.15 0.7831 0.8089 1166619 Maybridge3_000350 Fc1ccc(c(F)c1)S(=O)(=O)NCC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P21 compound treatment 0.339 0.0149 1.2 0.34 0.00467 0.42 1.1465 0.9024 2075365 Maybridge3_000351 Fc1ccc(OC(=O)c2c(Cl)cccc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P22 compound treatment 0.343 0.0189 1.52 0.344 0.00867 0.79 1.631 0.953 2075366 Maybridge3_000352 Clc1ccc2sc(Oc3cccc(c3)N4CCOCC4)nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P23 mock treatment 0.325 8.75E-4 0.07 0.333 -0.00233 -0.21 -0.0999 -0.4477 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1431 P24 positive control 0.094 -0.23 -18.53 0.093 -0.242 -22.0 -28.6577 -0.9964 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A01 compound treatment 0.312 -0.00581 -0.47 0.313 0.00294 0.27 -0.1424 -0.2644 2075367 Maybridge3_000353 Nc1nnc(Sc2nc3cc(Cl)ccc3s2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A02 compound treatment 0.319 0.00119 0.1 0.315 0.00494 0.45 0.3845 0.8391 1354581 Maybridge3_000354 CCCSc1nc(=O)c2cccnc2n1c3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A03 compound treatment 0.311 -0.00681 -0.55 0.333 0.0229 2.08 1.0843 0.5036 2075368 Maybridge3_000355 Cc1nn(C)c2oc(=O)cc(c3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A04 compound treatment 0.31 -0.00781 -0.63 0.308 -0.00206 -0.19 -0.5772 -0.8794 2075369 Maybridge3_000356 Cc1ccc(cc1)S(=O)(=O)CC(=O)Nc2ccc(F)c(F)c2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A05 compound treatment 0.306 -0.0118 -0.95 0.304 -0.00606 -0.55 -1.0617 -0.9662 2075370 Maybridge3_000357 CCOC(=O)CSc1cc(C)c(Cl)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A06 compound treatment 0.311 -0.00681 -0.55 0.305 -0.00506 -0.46 -0.7128 -0.9961 1298817 Maybridge3_000358 CC(C)(C)c1cc(cc(c1)C(=O)Oc2cccnc2)C(=O)Oc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A07 compound treatment 0.305 -0.0128 -1.03 0.296 -0.0141 -1.28 -1.6322 -0.9944 2075371 Maybridge3_000359 CN(C(=O)CSc1cc(Cl)ccc1Cl)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A08 compound treatment 0.306 -0.0118 -0.95 0.3 -0.0101 -0.91 -1.3185 -0.9998 2075372 Maybridge3_000360 COc1cc(C)nc2nc(SC)nn12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A09 compound treatment 0.313 -0.00481 -0.39 0.308 -0.00206 -0.19 -0.4064 -0.9443 1661500 Maybridge3_000361 CC(=O)Nc1ccccc1c2nnc(o2)c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A10 compound treatment 0.304 -0.0138 -1.11 0.298 -0.0121 -1.09 -1.5607 -1.0 1284592 Maybridge3_000362 COC(=O)CNC(=O)c1cccnc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A11 compound treatment 0.306 -0.0118 -0.95 0.303 -0.00706 -0.64 -1.1259 -0.9816 1345631 Maybridge3_000363 Cc1onc(c1NC(=O)Oc2ccc(CC#N)cc2)c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A12 compound treatment 0.31 -0.00781 -0.63 0.319 0.00894 0.81 0.1288 0.1255 2075373 Maybridge3_000364 CSc1ncccc1C2=N/C(=C\c3ccc(cc3)C(F)(F)F)/C(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A13 compound treatment 0.305 -0.0128 -1.03 0.303 -0.00706 -0.64 -1.1829 -0.9738 2075374 Maybridge3_000365 Clc1ccc(cc1)S(=O)(=O)n2ccc(c2)c3cnc4ccccc4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A14 compound treatment 0.272 -0.0458 -3.69 0.277 -0.0331 -3.0 -4.7307 -0.9948 1474356 Maybridge3_000366 Clc1cccc(c1)C(=O)OCCS(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A15 compound treatment 0.353 0.0352 2.83 0.324 0.0139 1.27 2.8982 0.934 2075375 Maybridge3_000367 O/N=C/Nc1cc(Cl)c(cc1Cl)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A16 compound treatment 0.323 0.00519 0.42 0.324 0.0139 1.27 1.19 0.8932 2075376 Maybridge3_000368 CSC1=C(C#N)C(=C(C#N)C#N)NC(=N1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A17 compound treatment 0.303 -0.0148 -1.19 0.301 -0.00906 -0.82 -1.4251 -0.9835 2075377 Maybridge3_000369 Clc1cncc(Oc2ccc(cn2)n3cccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A18 compound treatment 0.303 -0.0148 -1.19 0.303 -0.00706 -0.64 -1.2967 -0.9576 1401952 Maybridge3_000370 CCOC(=O)c1c(C)c(C#N)c(N)n1c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A19 compound treatment 0.307 -0.0108 -0.87 0.31 -6.25E-5 -0.01 -0.6197 -0.7117 2075378 Maybridge3_000371 FC(F)(F)c1ccc(SCCNC(=O)c2ccc(Cl)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A20 compound treatment 0.313 -0.00481 -0.39 0.308 -0.00206 -0.19 -0.4064 -0.9443 1135908 Maybridge3_000372 CN(C(=O)CSc1ccccn1)c2c3CCCCc3nn2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A21 compound treatment 0.301 -0.0168 -1.35 0.298 -0.0121 -1.09 -1.7316 -0.9945 2075379 Maybridge3_000373 CC(=C)C(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A22 compound treatment 0.306 -0.0118 -0.95 0.307 -0.00306 -0.28 -0.8692 -0.8771 2075380 Maybridge3_000374 Cn1nc(OC(C)(C)C(=O)O)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A23 mock treatment 0.301 -0.0168 -1.35 0.296 -0.0141 -1.28 -1.8599 -0.9996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 A24 positive control 0.081 -0.237 -19.07 0.08 -0.23 -20.88 -28.2509 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B01 compound treatment 0.336 0.0182 1.46 0.337 0.0269 2.45 2.7646 0.97 1206250 Maybridge3_000375 OC(=O)C1CC1C(=O)Nc2ccc(Oc3ccc(F)cc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B02 compound treatment 0.337 0.0192 1.55 0.333 0.0229 2.08 2.5648 0.9892 1921490 Maybridge3_000376 O=C(Nc1ccccc1)/C=C/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B03 compound treatment 0.337 0.0192 1.55 0.326 0.0159 1.45 2.1155 0.9995 2075381 Maybridge3_000377 COc1ccc(cc1)/C(=C/c2cn[nH]c2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B04 compound treatment 0.337 0.0192 1.55 0.33 0.0199 1.81 2.3722 0.9969 1002705 Maybridge3_000378 CC1(C)OC2OC(C(O)CO)C(O)C2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B05 compound treatment 0.336 0.0182 1.46 0.322 0.0119 1.08 1.8018 0.989 2075382 Maybridge3_000379 O/N=C/c1c[nH]c(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B06 compound treatment 0.329 0.0112 0.9 0.324 0.0139 1.27 1.5316 0.9862 1260437 Maybridge3_000380 O=C(N(c1ccccc1)c2ccccc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B07 compound treatment 0.331 0.0132 1.06 0.329 0.0189 1.72 1.9664 0.9732 2075383 Maybridge3_000381 CCCc1cc(=O)c2ccc(OC/C(=N/O)/C)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B08 compound treatment 0.332 0.0142 1.14 0.326 0.0159 1.45 1.8308 0.9932 1425483 Maybridge3_000382 CCC(=O)c1ccc(NC(=O)C)cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B09 compound treatment 0.331 0.0132 1.06 0.327 0.0169 1.54 1.838 0.9837 1184940 Maybridge3_000383 OCc1cc(=O)c(OCc2ccccc2)c[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B10 compound treatment 0.708 0.39 31.42 0.684 0.374 33.94 46.2188 0.9993 2075384 Maybridge3_000384 CSC1=N/C(=C/c2cccs2)/C(=O)N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B11 compound treatment 0.332 0.0142 1.14 0.327 0.0169 1.54 1.895 0.9893 1153981 Maybridge3_000385 CC(O)c1ccccc1c2ccccc2C(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B12 compound treatment 0.328 0.0102 0.82 0.323 0.0129 1.17 1.4105 0.9846 1084431 Maybridge3_000386 CC1(CC1(Br)Br)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B13 compound treatment 0.338 0.0202 1.63 0.328 0.0179 1.63 2.3008 1.0 1452761 Maybridge3_000387 O=C(N1CCCCC1)c2cccc3C(=O)c4ccccc4-c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B14 compound treatment 0.331 0.0132 1.06 0.319 0.00894 0.81 1.3246 0.9912 1006126 Maybridge3_000388 COC(=O)c1cccc2-c3ccccc3C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B15 compound treatment 0.32 0.00219 0.18 0.317 0.00694 0.63 0.5698 0.8715 1691637 Maybridge3_000389 CCc1ccc(cc1)n2nnnc2c3cn[nH]c3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B16 compound treatment 0.327 0.00919 0.74 0.323 0.0129 1.17 1.3535 0.9752 1020878 Maybridge3_000390 CNC(=O)Oc1cccc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B17 compound treatment 0.336 0.0182 1.46 0.326 0.0159 1.45 2.0586 1.0 1294341 Maybridge3_000391 CCNC(=O)c1ccccc1Sc2ccccc2COC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B18 compound treatment 0.33 0.0122 0.98 0.328 0.0179 1.63 1.8453 0.9706 1016816 Maybridge3_000392 CC(=O)NC(CCc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B19 compound treatment 0.328 0.0102 0.82 0.323 0.0129 1.17 1.4105 0.9846 1511758 Maybridge3_000393 CC(=O)NCc1ccccc1S(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B20 compound treatment 0.328 0.0102 0.82 0.326 0.0159 1.45 1.603 0.9639 1461606 Maybridge3_000394 COc1ccc(cc1)N(C(=C)C2CC2)C(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B21 compound treatment 0.33 0.0122 0.98 0.327 0.0169 1.54 1.7811 0.9765 1115519 Maybridge3_000395 CSc1nc2nc(C)cc(O)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B22 compound treatment 0.353 0.0352 2.83 0.343 0.0329 2.99 4.1177 0.9996 1178621 Maybridge3_000396 COn1c2CCCCc2c3c1ccc4nonc43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B23 mock treatment 0.324 0.00619 0.5 0.313 0.00294 0.27 0.5409 0.9571 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 B24 positive control 0.081 -0.237 -19.07 0.08 -0.23 -20.88 -28.2509 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C01 compound treatment 0.335 0.0172 1.38 0.332 0.0219 1.99 2.3867 0.9842 2075385 Maybridge3_000397 Cc1cc(C)n(n1)c2ccc(nn2)N3CCSCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C02 compound treatment 0.33 0.0122 0.98 0.327 0.0169 1.54 1.7811 0.9765 2075386 Maybridge3_000398 CN(c1ccc(Br)cc1)c2nc(=O)c3cccnc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C03 compound treatment 0.337 0.0192 1.55 0.327 0.0169 1.54 2.1797 1.0 1582616 Maybridge3_000399 CCOC(=O)Cc1csc(NS(=O)(=O)c2cc(C)c(Cl)cc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C04 compound treatment 0.318 1.88E-4 0.02 0.312 0.00194 0.18 0.135 0.765 2075387 Maybridge3_000400 Fc1ccc(cc1Cl)S(=O)(=O)/C=C/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C05 compound treatment 0.328 0.0102 0.82 0.321 0.0109 0.99 1.2821 0.9955 1293762 Maybridge3_000401 Cc1cc(Oc2ncccc2C(=O)O)cc(C)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C06 compound treatment 0.296 -0.0218 -1.76 0.286 -0.0241 -2.18 -2.7865 -0.9942 2075388 Maybridge3_000402 Cc1ccc(NC(=O)OCCS(=O)(=O)c2ccc(cn2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C07 compound treatment 0.318 1.88E-4 0.02 0.311 9.37E-4 0.09 0.0708 0.8198 2075389 Maybridge3_000403 O/N=C/Nc1ccccc1Sc2nc3cc(Cl)ccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C08 compound treatment 0.33 0.0122 0.98 0.318 0.00794 0.72 1.2034 0.9885 2075390 Maybridge3_000404 OC(=O)CSc1cccc(Cl)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C09 compound treatment 0.324 0.00619 0.5 0.313 0.00294 0.27 0.5409 0.9571 1053033 Maybridge3_000405 O=S(=O)(c1ccccc1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C10 compound treatment 0.322 0.00419 0.34 0.315 0.00494 0.45 0.5554 0.9902 1189912 Maybridge3_000406 COC(=O)CNC(=O)c1cccnc1Sc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C11 compound treatment 0.319 0.00119 0.1 0.315 0.00494 0.45 0.3845 0.8391 2075391 Maybridge3_000407 Clc1cc2ncc(nc2cc1Cl)c3ccn(c3)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C12 compound treatment 0.324 0.00619 0.5 0.318 0.00794 0.72 0.8618 0.9838 1216248 Maybridge3_000408 OC(=O)CNC(=O)c1cccnc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C13 compound treatment 0.321 0.00319 0.26 0.317 0.00694 0.63 0.6268 0.9217 1597701 Maybridge3_000409 Cc1cccc(NC(=O)c2ccc(Cl)cc2N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C14 compound treatment 0.32 0.00219 0.18 0.319 0.00894 0.81 0.6982 0.841 2075392 Maybridge3_000410 CSc1nc(nc(SC)c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C15 compound treatment 0.33 0.0122 0.98 0.321 0.0109 0.99 1.396 1.0 1676336 Maybridge3_000411 CSc1nnc(SC)n1CCNC(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C16 compound treatment 0.331 0.0132 1.06 0.32 0.00994 0.9 1.3887 0.9967 2075393 Maybridge3_000412 CN(C)c1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C17 compound treatment 0.326 0.00819 0.66 0.316 0.00594 0.54 0.8473 0.995 2075394 Maybridge3_000413 COc1ccc(cc1)n2cc(C#N)c(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C18 compound treatment 0.311 -0.00681 -0.55 0.303 -0.00706 -0.64 -0.8412 -0.997 2075395 Maybridge3_000414 CCOC(=O)c1c(C)c(C#N)c(n2cccc2)n1c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C19 compound treatment 0.324 0.00619 0.5 0.314 0.00394 0.36 0.6051 0.9867 2075396 Maybridge3_000415 OCCS(=O)(=O)c1ccc(cn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C20 compound treatment 0.326 0.00819 0.66 0.32 0.00994 0.9 1.104 0.9881 1461156 Maybridge3_000416 COc1ccc(Sc2nc(C)c(cc2C#N)c3csc(C)n3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C21 compound treatment 0.313 -0.00481 -0.39 0.308 -0.00206 -0.19 -0.4064 -0.9443 2075397 Maybridge3_000417 FC(F)(F)c1ccc(SCC(=O)c2cccc(c2)C(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C22 compound treatment 0.324 0.00619 0.5 0.319 0.00894 0.81 0.926 0.9726 2075398 Maybridge3_000418 Cn1nc(OC(C)(C)C(=O)Nc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C23 mock treatment 0.313 -0.00481 -0.39 0.304 -0.00606 -0.55 -0.6631 -0.9853 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 C24 positive control 0.084 -0.234 -18.83 0.081 -0.229 -20.79 -28.0159 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D01 compound treatment 0.343 0.0252 2.03 0.333 0.0229 2.08 2.9064 0.9999 1536821 Maybridge3_000419 Nc1nc(cs1)c2ccc3NC(=O)CCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D02 compound treatment 0.339 0.0212 1.71 0.336 0.0259 2.35 2.8712 0.9875 2075399 Maybridge3_000420 OC(=O)/C(=C/C(=O)c1ccccc1)/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D03 compound treatment 0.342 0.0242 1.95 0.338 0.0279 2.54 3.1704 0.9915 2075400 Maybridge3_000421 COC(=O)/C(=C\Nc1ccc(Sc2ccc(Cl)cc2)nc1)/NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D04 compound treatment 0.337 0.0192 1.55 0.327 0.0169 1.54 2.1797 1.0 1031898 Maybridge3_000422 CC1(C)OCC(O1)C(O)C(O)C2COC(C)(C)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D05 compound treatment 0.332 0.0142 1.14 0.334 0.0239 2.17 2.3443 0.9549 1325167 Maybridge3_000423 CN1C2CCC1CC(C2)NC(=O)c3c(F)cccc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D06 compound treatment 0.33 0.0122 0.98 0.326 0.0159 1.45 1.7169 0.9821 1092418 Maybridge3_000424 OCc1ccccc1Sc2ccccc2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D07 compound treatment 0.342 0.0242 1.95 0.334 0.0239 2.17 2.9137 0.9985 1360357 Maybridge3_000425 Cc1cc(=O)oc2c(CC=C)c(O)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D08 compound treatment 0.335 0.0172 1.38 0.325 0.0149 1.36 1.9374 0.9999 1038220 Maybridge3_000426 Oc1ccc(cc1)C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D09 compound treatment 0.332 0.0142 1.14 0.33 0.0199 1.81 2.0875 0.9754 2075401 Maybridge3_000427 COc1cccc(NC(=O)C(C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D10 compound treatment 0.35 0.0322 2.59 0.344 0.0339 3.08 4.0111 0.9963 2075402 Maybridge3_000428 C/C(=C/1\N=C(OC1=O)c2ccccc2)/Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D11 compound treatment 0.319 0.00119 0.1 0.309 -0.00106 -0.1 -6.0E-4 -0.0043 2075403 Maybridge3_000429 c1cc(sc1c2ccccn2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D12 compound treatment 0.329 0.0112 0.9 0.321 0.0109 0.99 1.339 0.9988 2075404 Maybridge3_000430 CC(CC(=O)c1cccs1)C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D13 compound treatment 0.333 0.0152 1.22 0.324 0.0139 1.27 1.7594 0.9999 1537471 Maybridge3_000431 Oc1c(Cc2ccccc2)c(=O)n3CCCc4cccc1c43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D14 compound treatment 0.322 0.00419 0.34 0.318 0.00794 0.72 0.7479 0.9402 2075405 Maybridge3_000432 CC(C)OC(=O)c1cccc2-c3ccccc3C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D15 compound treatment 0.072 -0.246 -19.79 0.099 -0.211 -19.16 -27.5438 -0.9999 2075406 Maybridge3_000433 Fc1ccc(cc1)C(=O)/C=C/S(=O)(=O)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D16 compound treatment 0.328 0.0102 0.82 0.319 0.00894 0.81 1.1537 1.0 2075407 Maybridge3_000434 CCCC(=O)Oc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D17 compound treatment 0.333 0.0152 1.22 0.328 0.0179 1.63 2.0161 0.9901 1272565 Maybridge3_000435 CNC(=O)c1ccccc1Sc2ccc(Cl)cc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D18 compound treatment 0.322 0.00419 0.34 0.32 0.00994 0.9 0.8763 0.9099 1116545 Maybridge3_000436 CC(N)C(=O)OCc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D19 compound treatment 0.33 0.0122 0.98 0.323 0.0129 1.17 1.5244 0.996 1407680 Maybridge3_000437 OCCc1ccccc1S(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D20 compound treatment 0.326 0.00819 0.66 0.319 0.00894 0.81 1.0399 0.9947 1488771 Maybridge3_000438 Nc1ccc(Oc2cccc(Oc3ccc(N)cc3)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D21 compound treatment 0.327 0.00919 0.74 0.326 0.0159 1.45 1.5461 0.9515 1095526 Maybridge3_000439 OC1C=COC2COC(OC12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D22 compound treatment 0.329 0.0112 0.9 0.324 0.0139 1.27 1.5316 0.9862 2075408 Maybridge3_000440 CC1(C)NC(C)(C)C(=C1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D23 mock treatment 0.316 -0.00181 -0.15 0.313 0.00294 0.27 0.0853 0.2807 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 D24 positive control 0.085 -0.233 -18.75 0.083 -0.227 -20.61 -27.8306 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E01 compound treatment 0.344 0.0262 2.11 0.336 0.0259 2.35 3.1559 0.9985 1396970 Maybridge3_000441 CC1CCN(CC1)c2ccc(nn2)n3nc(C)cc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E02 compound treatment 0.4 0.0822 6.62 0.388 0.0779 7.07 9.6822 0.9994 2075409 Maybridge3_000442 O=C(CSc1ssc(=S)c1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E03 compound treatment 0.342 0.0242 1.95 0.333 0.0229 2.08 2.8495 0.9994 1322883 Maybridge3_000443 CC(Sc1ncccc1C(=O)O)c2cc(C)ccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E04 compound treatment 0.376 0.0582 4.69 0.369 0.0589 5.35 7.0962 0.9978 1644141 Maybridge3_000444 CN(C)C=C=C(O)c1ccccc1C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E05 compound treatment 0.334 0.0162 1.3 0.33 0.0199 1.81 2.2014 0.987 2075410 Maybridge3_000445 CCCc1cc(O)nc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E06 compound treatment 0.247 -0.0708 -5.7 0.233 -0.0771 -7.0 -8.9784 -0.9949 2075411 Maybridge3_000446 CC(=O)OCCS(=O)(=O)c1ccc(cn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E07 compound treatment 0.33 0.0122 0.98 0.32 0.00994 0.9 1.3318 0.9991 2075412 Maybridge3_000447 Cc1cc(=O)oc2n(C)nc(c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E08 compound treatment 0.333 0.0152 1.22 0.327 0.0169 1.54 1.9519 0.9936 1691409 Maybridge3_000448 COC(=O)CNC(=O)c1cccnc1SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E09 compound treatment 0.337 0.0192 1.55 0.329 0.0189 1.72 2.3081 0.9986 1455911 Maybridge3_000449 Cc1nn(nc1C(=O)Oc2ccc(CC#N)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E10 compound treatment 0.338 0.0202 1.63 0.337 0.0269 2.45 2.8785 0.9803 1176197 Maybridge3_000450 COC(=O)CNC(=O)c1cccnc1Oc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E11 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 2075413 Maybridge3_000451 Cc1ccc(Sc2ccc(N)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E12 compound treatment 0.33 0.0122 0.98 0.314 0.00394 0.36 0.9467 0.9064 2075414 Maybridge3_000452 Cc1cc(OCC(=O)c2ccc(cc2)C(F)(F)F)n3cnnc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E13 compound treatment 0.323 0.00519 0.42 0.315 0.00494 0.45 0.6123 0.9994 1231742 Maybridge3_000453 N#CCc1cccc(OCc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E14 compound treatment 0.305 -0.0128 -1.03 0.313 0.00294 0.27 -0.541 -0.5077 2075415 Maybridge3_000454 CSc1nc(nc(Nc2ccccc2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E15 compound treatment 0.34 0.0222 1.79 0.33 0.0199 1.81 2.5431 1.0 1386414 Maybridge3_000455 CSc1nnc(SC)n1CCNS(=O)(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E16 compound treatment 0.306 -0.0118 -0.95 0.313 0.00294 0.27 -0.4841 -0.49 2075416 Maybridge3_000456 Clc1ccc(SCCOC(=O)c2cccc(Cl)c2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E17 compound treatment 0.34 0.0222 1.79 0.335 0.0249 2.26 2.864 0.9931 2075417 Maybridge3_000457 Cc1cc(ccc1Cl)c2csc(=S)n2Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E18 compound treatment 0.256 -0.0618 -4.98 0.259 -0.0511 -4.64 -6.7971 -0.9994 2075418 Maybridge3_000458 Cc1cc(cc(n1)S(=O)(=O)CCOC(=O)c2cccc(Cl)c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E19 compound treatment 0.321 0.00319 0.26 0.321 0.0109 0.99 0.8835 0.8616 2075419 Maybridge3_000459 N/C(=N\O)/CC(=O)Nc1ccc(F)c(F)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E20 compound treatment 0.317 -8.12E-4 -0.07 0.314 0.00394 0.36 0.2065 0.5682 1540377 Maybridge3_000460 O=C(CSc1ccccc1)c2ccc3NC(=O)CCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E21 compound treatment 0.354 0.0362 2.91 0.352 0.0419 3.81 4.7523 0.9913 2075420 Maybridge3_000461 CSC1=C(C(=SS1)SC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E22 compound treatment 0.322 0.00419 0.34 0.316 0.00594 0.54 0.6195 0.9745 2075421 Maybridge3_000462 Cn1nc(OCC(=O)O)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E23 mock treatment 0.312 -0.00581 -0.47 0.305 -0.00506 -0.46 -0.6559 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 E24 positive control 0.088 -0.23 -18.51 0.085 -0.225 -20.43 -27.5314 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F01 compound treatment 0.357 0.0392 3.16 0.348 0.0379 3.44 4.6664 0.999 2075422 Maybridge3_000463 O/N=C/Nc1nc(cs1)c2ccc3NC(=O)CCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F02 compound treatment 0.338 0.0202 1.63 0.329 0.0189 1.72 2.365 0.9996 1508220 Maybridge3_000464 Oc1c(c2ccccc2)c(=O)[nH]c3cc(F)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F03 compound treatment 0.335 0.0172 1.38 0.327 0.0169 1.54 2.0658 0.9986 2075423 Maybridge3_000465 FC(F)(F)c1cc(Br)c2[nH]c(=O)c(=O)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F04 compound treatment 0.336 0.0182 1.46 0.334 0.0239 2.17 2.572 0.9816 2075424 Maybridge3_000466 CC(C)SC1OC(CO)C(O)C(O)C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F05 compound treatment 0.344 0.0262 2.11 0.333 0.0229 2.08 2.9634 1.0 1273132 Maybridge3_000467 COc1ccccc1CC(=O)NC2CC3CCC(C2)N3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F06 compound treatment 0.343 0.0252 2.03 0.326 0.0159 1.45 2.4571 0.9863 2075425 Maybridge3_000468 CC(=O)Nc1ccccc1OCCOc2ccccc2NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F07 compound treatment 0.332 0.0142 1.14 0.326 0.0159 1.45 1.8308 0.9932 1315554 Maybridge3_000469 CCCc1cc(=O)c2c(O)cccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F08 compound treatment 0.334 0.0162 1.3 0.333 0.0229 2.08 2.394 0.9746 1133392 Maybridge3_000470 O=c1c(Cc2ccccc2)coc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F09 compound treatment 0.324 0.00619 0.5 0.329 0.0189 1.72 1.5678 0.876 1004558 Maybridge3_000471 CN(C)C(c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F10 compound treatment 0.33 0.0122 0.98 0.316 0.00594 0.54 1.0751 0.9602 2075426 Maybridge3_000472 CC1CCCC1/C(=N/O)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F11 compound treatment 0.325 0.00719 0.58 0.327 0.0169 1.54 1.4964 0.9109 1635865 Maybridge3_000473 OC(=O)CCCc1ccc2OCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F12 compound treatment 0.337 0.0192 1.55 0.322 0.0119 1.08 1.8588 0.9849 1600318 Maybridge3_000474 CCOC(=O)COc1ccccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F13 compound treatment 0.339 0.0212 1.71 0.327 0.0169 1.54 2.2936 0.9986 1026021 Maybridge3_000475 Cc1nc2ccccc2c(=O)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F14 compound treatment 0.335 0.0172 1.38 0.329 0.0189 1.72 2.1942 0.9942 1081820 Maybridge3_000476 CC(C)NC(=O)Oc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F15 compound treatment 0.331 0.0132 1.06 0.326 0.0159 1.45 1.7739 0.9884 1476519 Maybridge3_000477 CNC(=O)c1cccc2cccc(Sc3ccccc3C(=O)O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F16 compound treatment 0.327 0.00919 0.74 0.327 0.0169 1.54 1.6103 0.9438 1494580 Maybridge3_000478 Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)C4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F17 compound treatment 0.332 0.0142 1.14 0.322 0.0119 1.08 1.5741 0.9997 1725347 Maybridge3_000479 OC(=O)CCSc1ccccc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F18 compound treatment 0.323 0.00519 0.42 0.323 0.0129 1.17 1.1258 0.9032 1051989 Maybridge3_000480 Fc1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F19 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 1534976 Maybridge3_000481 CC(=O)N1Cc2ccccc2S31OC(=O)c4ccccc43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F20 compound treatment 0.331 0.0132 1.06 0.322 0.0119 1.08 1.5171 0.9999 1570526 Maybridge3_000482 COC(=O)C1=C(N)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F21 compound treatment 0.327 0.00919 0.74 0.325 0.0149 1.36 1.4819 0.9594 2075427 Maybridge3_000483 CC(=O)NC(c1ccc(Cl)cc1)n2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F22 compound treatment 0.329 0.0112 0.9 0.327 0.0169 1.54 1.7242 0.9676 1077803 Maybridge3_000484 COc1cc(CC(=O)O)ccc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F23 mock treatment 0.32 0.00219 0.18 0.307 -0.00306 -0.28 -0.072 -0.2188 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 F24 positive control 0.087 -0.231 -18.59 0.085 -0.225 -20.43 -27.5883 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G01 compound treatment 0.346 0.0282 2.27 0.329 0.0189 1.72 2.8205 0.9906 2075428 Maybridge3_000485 CC1CN(CC(C)O1)c2ccc(nn2)n3nc(C)cc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G02 compound treatment 0.337 0.0192 1.55 0.33 0.0199 1.81 2.3722 0.9969 2075429 Maybridge3_000486 Cc1cc(ccc1Cl)C(=O)CSc2c(F)c(F)c(C(=O)O)c(F)c2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G03 compound treatment 0.325 0.00719 0.58 0.32 0.00994 0.9 1.0471 0.977 1376755 Maybridge3_000487 CSc1ncccc1C(=O)NC(C)(C#N)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G04 compound treatment 0.328 0.0102 0.82 0.318 0.00794 0.72 1.0896 0.9979 1363604 Maybridge3_000488 Nc1ncccc1OCc2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G05 compound treatment 0.333 0.0152 1.22 0.328 0.0179 1.63 2.0161 0.9901 2075430 Maybridge3_000489 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2C(=O)NC3CCCCNC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G06 compound treatment 0.331 0.0132 1.06 0.321 0.0109 0.99 1.4529 0.9994 1142600 Maybridge3_000490 CCOC(=O)c1cnc2c(F)ccc(F)c2c1Oc3cncc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G07 compound treatment 0.328 0.0102 0.82 0.322 0.0119 1.08 1.3463 0.9906 2075431 Maybridge3_000491 NS(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G08 compound treatment 0.335 0.0172 1.38 0.322 0.0119 1.08 1.7449 0.9927 1303519 Maybridge3_000492 OC(=O)CNC(=O)c1cccnc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G09 compound treatment 0.338 0.0202 1.63 0.335 0.0249 2.26 2.7501 0.9868 1181739 Maybridge3_000493 Clc1c(sc2ccccc12)C(=O)Oc3ccc(CC#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G10 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 1627842 Maybridge3_000494 COC(=O)CNC(=O)c1cccnc1Oc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G11 compound treatment 0.358 0.0402 3.24 0.342 0.0319 2.9 4.3382 0.9985 1548800 Maybridge3_000495 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G12 compound treatment 0.334 0.0162 1.3 0.325 0.0149 1.36 1.8805 0.9998 2075432 Maybridge3_000496 OC(=O)CNC(=O)c1ccccc1N(CC=C)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G13 compound treatment 0.326 0.00819 0.66 0.319 0.00894 0.81 1.0399 0.9947 1461087 Maybridge3_000497 Cc1ccc(C)n1c2ncccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G14 compound treatment 0.331 0.0132 1.06 0.322 0.0119 1.08 1.5171 0.9999 2075433 Maybridge3_000498 CSc1nc(C)nc(Nc2ccccc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G15 compound treatment 0.329 0.0112 0.9 0.314 0.00394 0.36 0.8898 0.918 1218801 Maybridge3_000499 CCSc1ncccc1C(=O)Oc2cc(C)nn2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G16 compound treatment 0.327 0.00919 0.74 0.318 0.00794 0.72 1.0326 0.9999 2075434 Maybridge3_000500 CN(C)c1nc(nc(Nc2cccc(c2)C(F)(F)F)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G17 compound treatment 0.332 0.0142 1.14 0.328 0.0179 1.63 1.9592 0.985 2075435 Maybridge3_000501 FC(F)(F)c1ccc(cc1)C(=O)Oc2cccc3[nH]ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G18 compound treatment 0.339 0.0212 1.71 0.329 0.0189 1.72 2.4219 1.0 1668703 Maybridge3_000502 CCOC(=O)c1c(C)c(C#N)c(NC(=O)C(C)(C)C)n1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G19 compound treatment 0.323 0.00519 0.42 0.321 0.0109 0.99 0.9974 0.926 2075436 Maybridge3_000503 O/N=C/Nc1ncc(cc1Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G20 compound treatment 0.33 0.0122 0.98 0.322 0.0119 1.08 1.4602 0.9988 1419348 Maybridge3_000504 CC(C)(C)SCC(=O)c1ccc2NC(=O)CCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G21 compound treatment 0.319 0.00119 0.1 0.316 0.00594 0.54 0.4487 0.8198 2075437 Maybridge3_000505 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G22 compound treatment 0.323 0.00519 0.42 0.329 0.0189 1.72 1.5109 0.8541 2075438 Maybridge3_000506 Cn1nc(OCC(=O)Nc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G23 mock treatment 0.316 -0.00181 -0.15 0.311 9.37E-4 0.09 -0.043 -0.2547 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 G24 positive control 0.088 -0.23 -18.51 0.086 -0.224 -20.34 -27.4672 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H01 compound treatment 0.343 0.0252 2.03 0.331 0.0209 1.9 2.7781 0.9995 1528340 Maybridge3_000507 OCc1ccc(OCc2ccc(F)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H02 compound treatment 0.331 0.0132 1.06 0.331 0.0209 1.9 2.0948 0.9622 1058115 Maybridge3_000508 C(N1CCCCC1)n2c3ccccc3c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H03 compound treatment 0.336 0.0182 1.46 0.326 0.0159 1.45 2.0586 1.0 1676832 Maybridge3_000509 OC(=O)CC(C(=O)NCc1ccccc1)C2=CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H04 compound treatment 0.338 0.0202 1.63 0.331 0.0209 1.9 2.4934 0.997 1087972 Maybridge3_000510 OCC1OC(Sc2ccccc2)C(O)C(O)C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H05 compound treatment 0.332 0.0142 1.14 0.32 0.00994 0.9 1.4457 0.9932 1066281 Maybridge3_000511 c1ccc(cc1)c2cccc(n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H06 compound treatment 0.337 0.0192 1.55 0.332 0.0219 1.99 2.5006 0.9921 2075439 Maybridge3_000512 CC1(C)SC(NC1C(=O)O)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H07 compound treatment 0.341 0.0232 1.87 0.333 0.0229 2.08 2.7926 0.9985 1255440 Maybridge3_000513 CCCc1cc(=O)c2c(O)ccc(OC)c2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H08 compound treatment 0.327 0.00919 0.74 0.323 0.0129 1.17 1.3535 0.9752 1220272 Maybridge3_000514 O=C1C(COc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H09 compound treatment 0.334 0.0162 1.3 0.318 0.00794 0.72 1.4312 0.9609 1740369 Maybridge3_000515 OCC1c2ccccc2Oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H10 compound treatment 0.333 0.0152 1.22 0.333 0.0229 2.08 2.337 0.9678 1408710 Maybridge3_000516 COC(=O)C(CO)NS(=O)(=O)c1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H11 compound treatment 0.328 0.0102 0.82 0.316 0.00594 0.54 0.9612 0.9792 1524491 Maybridge3_000517 CC(=O)Nc1ccc-2c(CCc3ccccc32)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H12 compound treatment 0.337 0.0192 1.55 0.321 0.0109 0.99 1.7946 0.9771 2075440 Maybridge3_000518 CC1(C)CN=C(Nc2ccc(F)c(Cl)c2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H13 compound treatment 0.336 0.0182 1.46 0.323 0.0129 1.17 1.866 0.994 1072271 Maybridge3_000519 CC(=O)Nc1ccc(CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H14 compound treatment 0.306 -0.0118 -0.95 0.317 0.00694 0.63 -0.2273 -0.1993 1064797 Maybridge3_000520 O=C(NC1CCCCC1)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H15 compound treatment 0.345 0.0272 2.19 0.328 0.0179 1.63 2.6994 0.9894 1330529 Maybridge3_000521 CNC(=O)c1cccc2cccc(Sc3ccccc3C(=O)OC)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H16 compound treatment 0.329 0.0112 0.9 0.321 0.0109 0.99 1.339 0.9988 1425252 Maybridge3_000522 Cc1nnsc1C(=O)N2CCc3[nH]c4ccc(F)cc4c3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H17 compound treatment 0.329 0.0112 0.9 0.321 0.0109 0.99 1.339 0.9988 1731122 Maybridge3_000523 CCOC(=O)c1ccccc1Sc2ccccc2C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H18 compound treatment 0.326 0.00819 0.66 0.328 0.0179 1.63 1.6175 0.9208 2075441 Maybridge3_000524 NC1=C(C#N)C(C(=C(N)S1)C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H19 compound treatment 0.326 0.00819 0.66 0.32 0.00994 0.9 1.104 0.9881 2075442 Maybridge3_000525 CN1[S+](c2ccccc2C(=O)O)c3cccc4cccc(C1=O)c34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H20 compound treatment 0.33 0.0122 0.98 0.32 0.00994 0.9 1.3318 0.9991 1741501 Maybridge3_000526 OC(=O)c1ncccc1C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H21 compound treatment 0.324 0.00619 0.5 0.324 0.0139 1.27 1.2469 0.917 1081833 Maybridge3_000527 COC(=S)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H22 compound treatment 0.324 0.00619 0.5 0.318 0.00794 0.72 0.8618 0.9838 1016602 Maybridge3_000528 C1CN(CCO1)c2cc(nc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H23 mock treatment 0.318 1.88E-4 0.02 0.314 0.00394 0.36 0.2634 0.7363 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 H24 positive control 0.089 -0.229 -18.43 0.086 -0.224 -20.34 -27.4102 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I01 compound treatment 0.336 0.0182 1.46 0.326 0.0159 1.45 2.0586 1.0 2075443 Maybridge3_000529 Cc1cc(C)n(n1)c2ccc(SCc3ccc(Cl)cc3)nn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I02 compound treatment 0.363 0.0452 3.64 0.352 0.0419 3.81 5.2648 0.9997 2075444 Maybridge3_000530 FC(F)(F)Oc1ccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I03 compound treatment 0.322 0.00419 0.34 0.312 0.00194 0.18 0.3628 0.9539 2075445 Maybridge3_000531 Cc1cc(SCc2n[nH]c3oc(=O)cc(C)c23)c(C)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I04 compound treatment 0.333 0.0152 1.22 0.321 0.0109 0.99 1.5668 0.9946 2075446 Maybridge3_000532 COC(=O)CSc1nnc(SC)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I05 compound treatment 0.352 0.0342 2.75 0.341 0.0309 2.81 3.9324 1.0 1695135 Maybridge3_000533 CCCc1cc(OC(=O)c2cccnc2Oc3ccccc3)n(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I06 compound treatment 0.328 0.0102 0.82 0.321 0.0109 0.99 1.2821 0.9955 1325490 Maybridge3_000534 COc1ccc(Oc2ccc(NC(=O)Cc3cccs3)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I07 compound treatment 0.328 0.0102 0.82 0.32 0.00994 0.9 1.2179 0.9989 1625906 Maybridge3_000535 Clc1ccc(Cl)c(Oc2ccccc2NC(=O)CC#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I08 compound treatment 0.332 0.0142 1.14 0.329 0.0189 1.72 2.0234 0.9803 2075447 Maybridge3_000536 OC(=O)CSc1ccc(F)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I09 compound treatment 0.338 0.0202 1.63 0.316 0.00594 0.54 1.5306 0.8937 2075448 Maybridge3_000537 Clc1ccc(OC(=O)NC(=O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I10 compound treatment 0.332 0.0142 1.14 0.322 0.0119 1.08 1.5741 0.9997 1187652 Maybridge3_000538 COc1ccc(OC)c(SCC(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I11 compound treatment 0.334 0.0162 1.3 0.332 0.0219 1.99 2.3298 0.9789 2075449 Maybridge3_000539 FC(F)(F)c1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I12 compound treatment 0.336 0.0182 1.46 0.312 0.00194 0.18 1.16 0.7864 2075450 Maybridge3_000540 CSc1nc(C)[nH]c(=O)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I13 compound treatment 0.333 0.0152 1.22 0.321 0.0109 0.99 1.5668 0.9946 2075451 Maybridge3_000541 Clc1cncc(OC(=O)c2cc3ccccc3s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I14 compound treatment 0.301 -0.0168 -1.35 0.301 -0.00906 -0.82 -1.539 -0.9715 2075452 Maybridge3_000542 Clc1cccc(c1)C(=O)OCCSc2ncccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I15 compound treatment 0.312 -0.00581 -0.47 0.321 0.0109 0.99 0.3711 0.3381 2075453 Maybridge3_000543 Cc1cc(OC(=O)c2ccccc2)n(n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I16 compound treatment 0.331 0.0132 1.06 0.323 0.0129 1.17 1.5813 0.9987 2075454 Maybridge3_000544 CSc1nc(C)nc(N(C)C)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I17 compound treatment 0.338 0.0202 1.63 0.326 0.0159 1.45 2.1724 0.9983 1382015 Maybridge3_000545 Cc1ccc(cc1)C(=O)Oc2cccc3[nH]ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I18 compound treatment 0.34 0.0222 1.79 0.322 0.0119 1.08 2.0296 0.9713 1277053 Maybridge3_000546 NC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I19 compound treatment 0.329 0.0112 0.9 0.327 0.0169 1.54 1.7242 0.9676 2075455 Maybridge3_000547 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCNC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I20 compound treatment 0.334 0.0162 1.3 0.324 0.0139 1.27 1.8163 0.9999 1327270 Maybridge3_000548 Cc1nc(cs1)c2cc(C#N)c(NCc3ccccc3)nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I21 compound treatment 0.339 0.0212 1.71 0.325 0.0149 1.36 2.1652 0.9935 2075456 Maybridge3_000549 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I22 compound treatment 0.328 0.0102 0.82 0.327 0.0169 1.54 1.6672 0.9567 2075457 Maybridge3_000550 Cn1nc(OCC(=O)NC(C)(C)C)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I23 mock treatment 0.322 0.00419 0.34 0.312 0.00194 0.18 0.3628 0.9539 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 I24 positive control 0.09 -0.228 -18.34 0.086 -0.224 -20.34 -27.3533 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J01 compound treatment 0.338 0.0202 1.63 0.33 0.0199 1.81 2.4292 0.9986 1256256 Maybridge3_000551 Cc1cc(Cl)ccc1Oc2ncccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J02 compound treatment 0.335 0.0172 1.38 0.327 0.0169 1.54 2.0658 0.9986 2075458 Maybridge3_000552 CC(C)n1c2ccccc2c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J03 compound treatment 0.329 0.0112 0.9 0.319 0.00894 0.81 1.2107 0.9986 1244194 Maybridge3_000553 CC(=CC(=O)ON1C(=O)C2C3OC(C=C3)C2C1=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J04 compound treatment 0.349 0.0312 2.51 0.341 0.0309 2.81 3.7616 0.9984 2075459 Maybridge3_000554 COc1ccc(cc1)C(=O)/C=C/Nc2ccccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J05 compound treatment 0.331 0.0132 1.06 0.319 0.00894 0.81 1.3246 0.9912 2075460 Maybridge3_000555 COc1cc(CCC(C)NCc2ccccc2)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J06 compound treatment 0.328 0.0102 0.82 0.332 0.0219 1.99 1.9881 0.9231 2075461 Maybridge3_000556 c1ccc(cc1)c2cccnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J07 compound treatment 0.376 0.0582 4.69 0.369 0.0589 5.35 7.0962 0.9978 1553196 Maybridge3_000557 CCCc1c(N)ccc2c(=O)cc(oc12)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J08 compound treatment 0.326 0.00819 0.66 0.319 0.00894 0.81 1.0399 0.9947 1607994 Maybridge3_000558 COc1ccccc1c2coc3ccccc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J09 compound treatment 0.33 0.0122 0.98 0.32 0.00994 0.9 1.3318 0.9991 1541139 Maybridge3_000559 O=C(Oc1cccnc1)C2c3ccccc3Oc4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J10 compound treatment 0.33 0.0122 0.98 0.32 0.00994 0.9 1.3318 0.9991 1002178 Maybridge3_000560 CCOC(=O)C1CC(=O)C(CC1=O)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J11 compound treatment 0.329 0.0112 0.9 0.324 0.0139 1.27 1.5316 0.9862 2075462 Maybridge3_000561 COC(=O)Cc1nc(oc1C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J12 compound treatment 0.324 0.00619 0.5 0.321 0.0109 0.99 1.0543 0.9492 2075463 Maybridge3_000562 Cc1ccc(SC#N)c(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J13 compound treatment 0.326 0.00819 0.66 0.318 0.00794 0.72 0.9757 0.999 2075464 Maybridge3_000563 c1ccc(cc1)c2cnc(nc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J14 compound treatment 0.325 0.00719 0.58 0.331 0.0209 1.9 1.7531 0.8824 1019721 Maybridge3_000564 COc1ccc(NC(=O)Oc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J15 compound treatment 0.344 0.0262 2.11 0.349 0.0389 3.53 3.9903 0.9695 1367336 Maybridge3_000565 CNC(=O)c1ccccc1Sc2cccc3cccc(COC(=O)C)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J16 compound treatment 0.327 0.00919 0.74 0.322 0.0119 1.08 1.2894 0.9827 1164670 Maybridge3_000566 Cc1[nH]c2ccccc2c1CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J17 compound treatment 0.328 0.0102 0.82 0.325 0.0149 1.36 1.5388 0.971 1265803 Maybridge3_000567 OCc1cccc2cccc(S(=O)c3ccccc3C(=O)O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J18 compound treatment 0.33 0.0122 0.98 0.314 0.00394 0.36 0.9467 0.9064 2075465 Maybridge3_000568 CCN(CC)S(=O)(=O)C1CCS(=O)(=O)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J19 compound treatment 0.331 0.0132 1.06 0.325 0.0149 1.36 1.7097 0.9927 1431098 Maybridge3_000569 CC(=O)NC(=O)c1cccc2cccc(I)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J20 compound treatment 0.33 0.0122 0.98 0.326 0.0159 1.45 1.7169 0.9821 1588875 Maybridge3_000570 Oc1ccc2OC(CC(=O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J21 compound treatment 0.324 0.00619 0.5 0.326 0.0159 1.45 1.3753 0.8988 1462691 Maybridge3_000571 Oc1ccccc1N2C(=O)c3cccc4cccc(C2=O)c34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J22 compound treatment 0.311 -0.00681 -0.55 0.31 -6.25E-5 -0.01 -0.3919 -0.7144 1610135 Maybridge3_000572 CN(C)CCNc1cc(nc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J23 mock treatment 0.317 -8.12E-4 -0.07 0.312 0.00194 0.18 0.0781 0.4162 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 J24 positive control 0.09 -0.228 -18.34 0.088 -0.222 -20.16 -27.2249 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K01 compound treatment 0.34 0.0222 1.79 0.328 0.0179 1.63 2.4147 0.9989 2075466 Maybridge3_000573 Cc1cc(C)n(n1)c2ccc(SCC(=O)Nc3ccc(Cl)cc3)nn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K02 compound treatment 0.356 0.0382 3.08 0.35 0.0399 3.63 4.7378 0.9966 2075467 Maybridge3_000574 FC(F)(F)c1cccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K03 compound treatment 0.329 0.0112 0.9 0.326 0.0159 1.45 1.66 0.974 1376910 Maybridge3_000575 Cc1cc(=O)oc2n(nc(c3ccccc3)c12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K04 compound treatment 0.318 1.88E-4 0.02 0.316 0.00594 0.54 0.3918 0.7266 2075468 Maybridge3_000576 FC(F)(F)c1ccc(cc1)C(=O)OCCS(=O)(=O)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K05 compound treatment 0.335 0.0172 1.38 0.331 0.0209 1.9 2.3225 0.9879 1638249 Maybridge3_000577 Cc1cc(C)n(n1)c2ccc(cc2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K06 compound treatment 0.331 0.0132 1.06 0.318 0.00794 0.72 1.2604 0.9821 1231832 Maybridge3_000578 Clc1cc(Cl)cc(CNC(=O)Cc2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K07 compound treatment 0.331 0.0132 1.06 0.33 0.0199 1.81 2.0306 0.9677 2075469 Maybridge3_000579 CSc1ncccc1C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K08 compound treatment 0.321 0.00319 0.26 0.327 0.0169 1.54 1.2686 0.8139 2075470 Maybridge3_000580 OC(=O)CSc1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K09 compound treatment 0.323 0.00519 0.42 0.328 0.0179 1.63 1.4467 0.8606 2075471 Maybridge3_000581 Fc1cccc(F)c1OC(=O)NC(=O)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K10 compound treatment 0.332 0.0142 1.14 0.32 0.00994 0.9 1.4457 0.9932 2075472 Maybridge3_000582 Cc1cc(OCC(=O)c2cccc(c2)C(F)(F)F)n3cnnc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K11 compound treatment 0.331 0.0132 1.06 0.324 0.0139 1.27 1.6455 0.9962 2075473 Maybridge3_000583 Clc1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K12 compound treatment 0.328 0.0102 0.82 0.324 0.0139 1.27 1.4747 0.978 2075474 Maybridge3_000584 COC(=O)CSc1nc(C)nc(SC)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K13 compound treatment 0.323 0.00519 0.42 0.317 0.00694 0.63 0.7407 0.9801 2075475 Maybridge3_000585 Clc1cncc(OC(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K14 compound treatment 0.272 -0.0458 -3.69 0.266 -0.0441 -4.0 -5.4368 -0.9992 2075476 Maybridge3_000586 FC(F)(F)c1cccnc1S(=O)(=O)CCOC(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K15 compound treatment 0.336 0.0182 1.46 0.325 0.0149 1.36 1.9944 0.9993 1399454 Maybridge3_000587 COC(=O)c1c(OC)ccc(c1OC)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K16 compound treatment 0.329 0.0112 0.9 0.32 0.00994 0.9 1.2749 1.0 2075477 Maybridge3_000588 COC(=O)C(C)(C)S(=O)(=O)c1ccc(cn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K17 compound treatment 0.319 0.00119 0.1 0.313 0.00294 0.27 0.2562 0.9043 1203424 Maybridge3_000589 Fc1cccc(F)c1C(=O)Oc2cccc3[nH]ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K18 compound treatment 0.349 0.0312 2.51 0.342 0.0319 2.9 3.8258 0.9974 1414362 Maybridge3_000590 CC(=O)Nc1cc(C)ccc1OC(C)(C)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K19 compound treatment 0.328 0.0102 0.82 0.321 0.0109 0.99 1.2821 0.9955 2075478 Maybridge3_000591 Nc1cccnc1Oc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K20 compound treatment 0.36 0.0422 3.4 0.353 0.0429 3.9 5.1581 0.9977 1605002 Maybridge3_000592 CCOC(=O)c1[nH]c(Cc2[nH]c(C(=O)OCC)c(C)c2C)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K21 compound treatment 0.32 0.00219 0.18 0.321 0.0109 0.99 0.8266 0.8198 2075479 Maybridge3_000593 FC(F)(F)c1cccc(c1)S(=O)(=O)N(CCC#N)Cc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K22 compound treatment 0.325 0.00719 0.58 0.326 0.0159 1.45 1.4322 0.9192 2075480 Maybridge3_000594 CN(C)C(=O)C(C)(C)Oc1cc(n(C)n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K23 mock treatment 0.319 0.00119 0.1 0.31 -6.25E-5 -0.01 0.0636 0.664 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 K24 positive control 0.09 -0.228 -18.34 0.088 -0.222 -20.16 -27.2249 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L01 compound treatment 0.349 0.0312 2.51 0.337 0.0269 2.45 3.5048 0.9999 1636894 Maybridge3_000595 Cc1nc(c(o1)c2ccccc2)c3ccc(NC(=O)C(C)(C)C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L02 compound treatment 0.336 0.0182 1.46 0.329 0.0189 1.72 2.2511 0.9968 1057689 Maybridge3_000596 OCn1c2ccccc2c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L03 compound treatment 0.324 0.00619 0.5 0.321 0.0109 0.99 1.0543 0.9492 1250886 Maybridge3_000597 Clc1ccc(s1)C(=O)ON2C(=O)C3C4OC(C=C4)C3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L04 compound treatment 0.331 0.0132 1.06 0.319 0.00894 0.81 1.3246 0.9912 1337528 Maybridge3_000598 CCSc1ncc(c2nnnn2c3ccccc3)c(n1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L05 compound treatment 0.345 0.0272 2.19 0.332 0.0219 1.99 2.9561 0.9989 2075481 Maybridge3_000599 Cc1oc(nc1CCO)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L06 compound treatment 0.339 0.0212 1.71 0.314 0.00394 0.36 1.4592 0.8371 1416638 Maybridge3_000600 CCCCn1c(=O)cc(O)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L07 compound treatment 0.331 0.0132 1.06 0.327 0.0169 1.54 1.838 0.9837 1179929 Maybridge3_000601 COc1ccc(OCCN)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L08 compound treatment 0.332 0.0142 1.14 0.321 0.0109 0.99 1.5099 0.9976 2075482 Maybridge3_000602 COc1ccc(cc1)c2coc3ccccc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L09 compound treatment 0.318 1.88E-4 0.02 0.314 0.00394 0.36 0.2634 0.7363 1077052 Maybridge3_000603 O=C(C(SC#N)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L10 compound treatment 0.33 0.0122 0.98 0.327 0.0169 1.54 1.7811 0.9765 1077090 Maybridge3_000604 OC(=O)C1CC2CCC1C=C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L11 compound treatment 0.319 0.00119 0.1 0.327 0.0169 1.54 1.1548 0.7496 2075483 Maybridge3_000605 O=C(CCC(=O)c1ccccc1)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L12 compound treatment 0.326 0.00819 0.66 0.326 0.0159 1.45 1.4892 0.9367 2075484 Maybridge3_000606 O=c1ccc(no1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L13 compound treatment 0.329 0.0112 0.9 0.328 0.0179 1.63 1.7883 0.961 1703544 Maybridge3_000607 O=c1[nH]c2ccccc2c3oc(nc13)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L14 compound treatment 0.324 0.00619 0.5 0.326 0.0159 1.45 1.3753 0.8988 2075485 Maybridge3_000608 Clc1ccc(OC(=O)NCCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L15 compound treatment 0.324 0.00619 0.5 0.327 0.0169 1.54 1.4395 0.8907 1337655 Maybridge3_000609 CNC(=O)c1ccccc1Sc2cccc3cccc(C(=O)NC)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L16 compound treatment 0.427 0.109 8.79 0.367 0.0569 5.17 9.8718 0.9679 2075486 Maybridge3_000610 CSC(=S)Nc1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L17 compound treatment 0.331 0.0132 1.06 0.327 0.0169 1.54 1.838 0.9837 2075487 Maybridge3_000611 COC(=O)c1ccccc1S(=O)c2cccc3cccc(CO)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L18 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 2075488 Maybridge3_000612 OC(=O)CSC1CCS(=O)(=O)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L19 compound treatment 0.332 0.0142 1.14 0.324 0.0139 1.27 1.7024 0.9987 1640133 Maybridge3_000613 COc1ccc(NC(=O)C)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L20 compound treatment 0.333 0.0152 1.22 0.324 0.0139 1.27 1.7594 0.9999 2075489 Maybridge3_000614 Nc1nnc(Nc2ccc(Cl)cc2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L21 compound treatment 0.316 -0.00181 -0.15 0.314 0.00394 0.36 0.1495 0.3873 2075490 Maybridge3_000615 c1c(sc2nc(nnc12)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L22 compound treatment 0.332 0.0142 1.14 0.323 0.0129 1.17 1.6382 0.9999 1005928 Maybridge3_000616 Cc1ccc(CCC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L23 mock treatment 0.322 0.00419 0.34 0.315 0.00494 0.45 0.5554 0.9902 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 L24 positive control 0.091 -0.227 -18.26 0.09 -0.22 -19.98 -27.0396 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M01 compound treatment 0.338 0.0202 1.63 0.327 0.0169 1.54 2.2366 0.9996 2075491 Maybridge3_000617 Cn1cc(C(=O)Nc2ccc(F)c(Cl)c2)c(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M02 compound treatment 0.331 0.0132 1.06 0.323 0.0129 1.17 1.5813 0.9987 2075492 Maybridge3_000618 CSc1nc2nccc(NC(=O)c3cccc(C)c3)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M03 compound treatment 0.327 0.00919 0.74 0.323 0.0129 1.17 1.3535 0.9752 2075493 Maybridge3_000619 CCCc1cc(=O)oc2n(C)nc(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M04 compound treatment 0.307 -0.0108 -0.87 0.304 -0.00606 -0.55 -1.0048 -0.9755 2075494 Maybridge3_000620 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCOC(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M05 compound treatment 0.329 0.0112 0.9 0.321 0.0109 0.99 1.339 0.9988 2075495 Maybridge3_000621 Fc1ccc(CNC(=O)CC#N)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M06 compound treatment 0.331 0.0132 1.06 0.321 0.0109 0.99 1.4529 0.9994 1178380 Maybridge3_000622 Fc1ccc(c2ccc(CNC(=O)Cc3cccs3)o2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M07 compound treatment 0.334 0.0162 1.3 0.326 0.0159 1.45 1.9447 0.9986 1222852 Maybridge3_000623 O=C1CS(=O)(=O)N(Cc2ccccc2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M08 compound treatment 0.329 0.0112 0.9 0.323 0.0129 1.17 1.4674 0.9914 1529004 Maybridge3_000624 COc1ccc(OC)c(Sc2ncccc2C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M09 compound treatment 0.325 0.00719 0.58 0.32 0.00994 0.9 1.0471 0.977 2075496 Maybridge3_000625 Oc1ccc(cc1)/C(=C/c2ccc(cc2)C(F)(F)F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M10 compound treatment 0.324 0.00619 0.5 0.319 0.00894 0.81 0.926 0.9726 2075497 Maybridge3_000626 CSc1ncccc1C2=N/C(=C\c3ccc(Cl)cc3)/C(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M11 compound treatment 0.329 0.0112 0.9 0.322 0.0119 1.08 1.4032 0.9958 1507727 Maybridge3_000627 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(Oc3cccnc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M12 compound treatment 0.328 0.0102 0.82 0.322 0.0119 1.08 1.3463 0.9906 2075498 Maybridge3_000628 CSc1nc(nc(Sc2ccccc2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M13 compound treatment 0.319 0.00119 0.1 0.31 -6.25E-5 -0.01 0.0636 0.664 1127265 Maybridge3_000629 Clc1cc(Cl)cc(COc2ccc(CC#N)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M14 compound treatment 0.324 0.00619 0.5 0.324 0.0139 1.27 1.2469 0.917 2075499 Maybridge3_000630 CSC1=C(C#N)C(=C(C#N)C#N)NC(=N1)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M15 compound treatment 0.322 0.00419 0.34 0.318 0.00794 0.72 0.7479 0.9402 1645179 Maybridge3_000631 O=C(Nc1nnc(SCC#N)s1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M16 compound treatment 0.412 0.0942 7.58 0.399 0.0889 8.07 11.0716 0.9995 2075500 Maybridge3_000632 CC(C)(C(=O)Nc1ccccc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M17 compound treatment 0.331 0.0132 1.06 0.33 0.0199 1.81 2.0306 0.9677 1582377 Maybridge3_000633 CCOC(=O)c1cc(NC(=O)C)ccc1Oc2cncc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M18 compound treatment 0.323 0.00519 0.42 0.324 0.0139 1.27 1.19 0.8932 2075501 Maybridge3_000634 CC(C)(Oc1ccc(C#N)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M19 compound treatment 0.336 0.0182 1.46 0.336 0.0259 2.35 2.7004 0.9739 2075502 Maybridge3_000635 Fc1ccc(Oc2ccc(NC(=O)/C=C/c3ccccc3)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M20 compound treatment 0.322 0.00419 0.34 0.315 0.00494 0.45 0.5554 0.9902 2075503 Maybridge3_000636 CCCC1=C(C(=O)NC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M21 compound treatment 0.322 0.00419 0.34 0.321 0.0109 0.99 0.9405 0.8969 2075504 Maybridge3_000637 CCOC(=O)NC1=Nc2ccccc2NC=C1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M22 compound treatment 0.333 0.0152 1.22 0.325 0.0149 1.36 1.8236 0.9987 2075505 Maybridge3_000638 Cn1nc(OC(C)(C)C(=O)NC(C)(C)C)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M23 mock treatment 0.316 -0.00181 -0.15 0.309 -0.00106 -0.1 -0.1714 -0.9798 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 M24 positive control 0.092 -0.226 -18.18 0.09 -0.22 -19.98 -26.9827 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N01 compound treatment 0.339 0.0212 1.71 0.331 0.0209 1.9 2.5503 0.9986 2075506 Maybridge3_000639 CC(=CC(=O)Oc1ccc(cc1)n2nnnc2SCC=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N02 compound treatment 0.342 0.0242 1.95 0.329 0.0189 1.72 2.5928 0.9981 2075507 Maybridge3_000640 C(C1CS1)n2c3ccccc3c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N03 compound treatment 0.336 0.0182 1.46 0.326 0.0159 1.45 2.0586 1.0 2075508 Maybridge3_000641 FC(F)(F)Oc1ccc(CON2C(=O)C3C4OC(C=C4)C3C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N04 compound treatment 0.333 0.0152 1.22 0.329 0.0189 1.72 2.0803 0.9861 2075509 Maybridge3_000642 CCOC(=O)c1c(O)cc(C)[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N05 compound treatment 0.333 0.0152 1.22 0.327 0.0169 1.54 1.9519 0.9936 2075510 Maybridge3_000643 CN1C2CCC1CC(C2)NC(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N06 compound treatment 0.336 0.0182 1.46 0.329 0.0189 1.72 2.2511 0.9968 1447827 Maybridge3_000644 OC(=O)C(=C1C2CC3CC(C2)CC1C3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N07 compound treatment 0.329 0.0112 0.9 0.331 0.0209 1.9 1.9809 0.9418 1706281 Maybridge3_000645 CCOC(=O)c1c(C)[nH]c2ccc(OCC=C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N08 compound treatment 0.364 0.0462 3.72 0.365 0.0549 4.99 6.1561 0.9896 1203832 Maybridge3_000646 COc1ccc(Nc2nc3ccccc3nc2c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N09 compound treatment 0.329 0.0112 0.9 0.332 0.0219 1.99 2.0451 0.9357 1034187 Maybridge3_000647 OCc1ccccc1c2ccccc2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N10 compound treatment 0.324 0.00619 0.5 0.318 0.00794 0.72 0.8618 0.9838 1363311 Maybridge3_000648 CCOc1ccc(cc1)N2Cc3cc(OCC)ccc3N=C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N11 compound treatment 0.333 0.0152 1.22 0.329 0.0189 1.72 2.0803 0.9861 2075511 Maybridge3_000649 COc1cccc(c1)/C(=C/O)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N12 compound treatment 0.34 0.0222 1.79 0.331 0.0209 1.9 2.6072 0.9995 1698210 Maybridge3_000650 O=C(N1CCOCC1)c2cccc3Cc4ccccc4-c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N13 compound treatment 0.336 0.0182 1.46 0.327 0.0169 1.54 2.1227 0.9997 2075512 Maybridge3_000651 O=C1OCC(=C1)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N14 compound treatment 0.329 0.0112 0.9 0.331 0.0209 1.9 1.9809 0.9418 1185125 Maybridge3_000652 COc1ccc(OC(=O)NCCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N15 compound treatment 0.326 0.00819 0.66 0.326 0.0159 1.45 1.4892 0.9367 1092424 Maybridge3_000653 CNC(=O)c1ccccc1Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N16 compound treatment 0.426 0.108 8.71 0.408 0.0979 8.89 12.4464 0.9999 2075513 Maybridge3_000654 CSC(=S)Nc1ccc(NC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N17 compound treatment 0.33 0.0122 0.98 0.319 0.00894 0.81 1.2676 0.9955 1364067 Maybridge3_000655 CNC(=O)c1ccccc1S(=O)c2cccc3cccc(CO)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N18 compound treatment 0.333 0.0152 1.22 0.328 0.0179 1.63 2.0161 0.9901 1191735 Maybridge3_000656 COc1ccc(NC(CC(=O)C2CC2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N19 compound treatment 0.327 0.00919 0.74 0.327 0.0169 1.54 1.6103 0.9438 2075514 Maybridge3_000657 Cc1ccc(I)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N20 compound treatment 0.321 0.00319 0.26 0.32 0.00994 0.9 0.8193 0.8736 1028615 Maybridge3_000658 Nc1cc(Nc2ccc(Br)cc2)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N21 compound treatment 0.319 0.00119 0.1 0.307 -0.00306 -0.28 -0.1289 -0.4386 2075515 Maybridge3_000659 COc1ccc(cc1)c2cc3nnc(nc3s2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N22 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 2075516 Maybridge3_000660 CCOC(=O)c1cc(CO)cc(c1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N23 mock treatment 0.322 0.00419 0.34 0.311 9.37E-4 0.09 0.2986 0.8586 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 N24 positive control 0.091 -0.227 -18.26 0.09 -0.22 -19.98 -27.0396 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O01 compound treatment 0.359 0.0412 3.32 0.35 0.0399 3.63 4.9086 0.999 1916588 Maybridge3_000661 COC(=O)/C=C/1\Nc2ccccc2NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O02 compound treatment 0.342 0.0242 1.95 0.334 0.0239 2.17 2.9137 0.9985 2075517 Maybridge3_000662 COC(=O)CS(=O)(=O)c1nccn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O03 compound treatment 0.338 0.0202 1.63 0.33 0.0199 1.81 2.4292 0.9986 2075518 Maybridge3_000663 CCCc1cc(=O)oc2[nH]nc(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O04 compound treatment 0.357 0.0392 3.16 0.346 0.0359 3.26 4.538 0.9999 1733743 Maybridge3_000664 CC(C)(C)c1cc(cc(c1)C(=O)Nc2cccnc2)C(=O)Nc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O05 compound treatment 0.338 0.0202 1.63 0.329 0.0189 1.72 2.365 0.9996 2075519 Maybridge3_000665 CN(C(=O)CC#N)c1ccc(F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O06 compound treatment 0.343 0.0252 2.03 0.333 0.0229 2.08 2.9064 0.9999 1716609 Maybridge3_000666 CCOC(=O)c1cnc2onc(C)c2c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O07 compound treatment 0.34 0.0222 1.79 0.344 0.0339 3.08 3.4417 0.9664 1479341 Maybridge3_000667 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O08 compound treatment 0.34 0.0222 1.79 0.329 0.0189 1.72 2.4789 0.9998 1483580 Maybridge3_000668 Cc1ccc(Oc2ncccc2C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O09 compound treatment 0.332 0.0142 1.14 0.331 0.0209 1.9 2.1517 0.9703 2075520 Maybridge3_000669 COc1ccc(/C=C(\C#N)/c2ccc(O)cc2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O10 compound treatment 0.33 0.0122 0.98 0.324 0.0139 1.27 1.5885 0.9921 2075521 Maybridge3_000670 CSc1ncccc1C2=N/C(=C\c3ccc(C)cc3)/C(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O11 compound treatment 0.334 0.0162 1.3 0.329 0.0189 1.72 2.1372 0.9907 1150800 Maybridge3_000671 CC(=O)Nc1ccc(Oc2cccnc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O12 compound treatment 0.332 0.0142 1.14 0.331 0.0209 1.9 2.1517 0.9703 2075522 Maybridge3_000672 O=C(OCCSc1ccccn1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O13 compound treatment 0.327 0.00919 0.74 0.327 0.0169 1.54 1.6103 0.9438 1018990 Maybridge3_000673 O=C(C1COC(=O)C1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O14 compound treatment 0.331 0.0132 1.06 0.33 0.0199 1.81 2.0306 0.9677 1473988 Maybridge3_000674 Nc1n(nc2[nH]c(nc(=O)c12)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O15 compound treatment 0.338 0.0202 1.63 0.328 0.0179 1.63 2.3008 1.0 1287534 Maybridge3_000675 CC(=O)Nc1nnc(SCC#N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O16 compound treatment 0.334 0.0162 1.3 0.33 0.0199 1.81 2.2014 0.987 1469722 Maybridge3_000676 CCOC(=O)c1c(C)c2c(=O)[nH]cnc2n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O17 compound treatment 0.325 0.00719 0.58 0.325 0.0149 1.36 1.368 0.9279 2075523 Maybridge3_000677 Cc1ccc(cc1)C(=O)OCCSc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O18 compound treatment 0.334 0.0162 1.3 0.326 0.0159 1.45 1.9447 0.9986 1613952 Maybridge3_000678 Cc1[nH]c(=O)c(C#N)cc1c2csc(n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O19 compound treatment 0.32 0.00219 0.18 0.317 0.00694 0.63 0.5698 0.8715 2075524 Maybridge3_000679 Fc1ccc(Oc2ncccc2NC(=O)/C=C/c3ccccc3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O20 compound treatment 0.358 0.0402 3.24 0.349 0.0389 3.53 4.7875 0.999 1551430 Maybridge3_000680 CC(=O)N1CC(=C(C#N)C1O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O21 compound treatment 0.338 0.0202 1.63 0.331 0.0209 1.9 2.4934 0.997 1186844 Maybridge3_000681 CCCN(c1ccc(C)cc1)c2nc(=O)c3cccnc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O22 compound treatment 0.329 0.0112 0.9 0.324 0.0139 1.27 1.5316 0.9862 2075525 Maybridge3_000682 Cc1ccc(Oc2ccc(cn2)C(F)(F)F)c3CCCc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O23 mock treatment 0.328 0.0102 0.82 0.316 0.00594 0.54 0.9612 0.9792 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 O24 positive control 0.091 -0.227 -18.26 0.091 -0.219 -19.88 -26.9754 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P01 compound treatment 0.335 0.0172 1.38 0.332 0.0219 1.99 2.3867 0.9842 2075526 Maybridge3_000683 Oc1cc(ccn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P02 compound treatment 0.343 0.0252 2.03 0.339 0.0289 2.63 3.2916 0.9918 1151687 Maybridge3_000684 CC(=O)Oc1cc2sc(=O)oc2c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P03 compound treatment 0.328 0.0102 0.82 0.334 0.0239 2.17 2.1165 0.9113 1419965 Maybridge3_000685 Fc1cccc(Cl)c1CON2C(=O)C3C4OC(C=C4)C3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P04 compound treatment 0.335 0.0172 1.38 0.327 0.0169 1.54 2.0658 0.9986 2075527 Maybridge3_000686 CC(=O)Nc1ccc(OCCOc2ccc(NC(=O)C)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P05 compound treatment 0.339 0.0212 1.71 0.327 0.0169 1.54 2.2936 0.9986 1690708 Maybridge3_000687 CCOC(=O)c1cc(=O)c2c(O)cccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P06 compound treatment 0.322 0.00419 0.34 0.312 0.00194 0.18 0.3628 0.9539 1527724 Maybridge3_000688 CC(C)OC(=O)c1cccc2C(=O)c3ccccc3-c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P07 compound treatment 0.324 0.00619 0.5 0.328 0.0179 1.63 1.5036 0.8831 1338763 Maybridge3_000689 Oc1nc2ccccc2n(c3ccc(Cl)cc3)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P08 compound treatment 0.793 0.475 38.27 0.795 0.485 44.02 58.1833 0.9976 2075528 Maybridge3_000690 CSC1=N/C(=C/c2ccco2)/C(=O)N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P09 compound treatment 0.326 0.00819 0.66 0.324 0.0139 1.27 1.3608 0.9539 1009360 Maybridge3_000691 CC(C)C1CCC(C)CC1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P10 compound treatment 0.326 0.00819 0.66 0.32 0.00994 0.9 1.104 0.9881 2075529 Maybridge3_000692 OC1(CCCCC1)c2cccc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P11 compound treatment 0.33 0.0122 0.98 0.322 0.0119 1.08 1.4602 0.9988 1138107 Maybridge3_000693 CCN(CC)C(=O)c1cccc2C(=O)c3ccccc3-c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P12 compound treatment 0.333 0.0152 1.22 0.328 0.0179 1.63 2.0161 0.9901 1430738 Maybridge3_000694 CCN(CC)C(=O)c1cccc2-c3ccccc3C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P13 compound treatment 0.325 0.00719 0.58 0.323 0.0129 1.17 1.2397 0.9469 2075530 Maybridge3_000695 CCc1c(O)c2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P14 compound treatment 0.328 0.0102 0.82 0.322 0.0119 1.08 1.3463 0.9906 1051125 Maybridge3_000696 CNC(=O)Oc1cccc(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P15 compound treatment 0.324 0.00619 0.5 0.323 0.0129 1.17 1.1827 0.9271 1656319 Maybridge3_000697 CCNC(=O)c1ccccc1Sc2ccccc2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P16 compound treatment 0.327 0.00919 0.74 0.322 0.0119 1.08 1.2894 0.9827 1286529 Maybridge3_000698 Oc1c(c2ccccc2)c(=O)n(c3ccccc3)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P17 compound treatment 0.326 0.00819 0.66 0.322 0.0119 1.08 1.2324 0.9716 1429737 Maybridge3_000699 CNC(=O)c1ccccc1S(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P18 compound treatment 0.317 -8.12E-4 -0.07 0.322 0.0119 1.08 0.7199 0.6632 1600212 Maybridge3_000700 Cc1ccc(NC(CC(=O)C2CC2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P19 compound treatment 0.324 0.00619 0.5 0.324 0.0139 1.27 1.2469 0.917 1143166 Maybridge3_000701 Oc1cc(=O)n(c2ccccc2)c3CCCCc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P20 compound treatment 0.329 0.0112 0.9 0.325 0.0149 1.36 1.5958 0.9803 1066953 Maybridge3_000702 CSc1nc(C(=O)N)c(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P21 compound treatment 0.328 0.0102 0.82 0.325 0.0149 1.36 1.5388 0.971 2075531 Maybridge3_000703 Clc1ccc(cc1)c2cc3nnc(nc3s2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P22 compound treatment 0.326 0.00819 0.66 0.323 0.0129 1.17 1.2966 0.9627 2075532 Maybridge3_000704 CCC(=O)N1C2CC(C=C2)C1(C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P23 mock treatment 0.319 0.00119 0.1 0.313 0.00294 0.27 0.2562 0.9043 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1432 P24 positive control 0.093 -0.225 -18.1 0.093 -0.217 -19.7 -26.7332 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A01 compound treatment 0.311 -0.00506 -0.41 0.308 -0.0111 -1.01 -1.0029 -0.9203 1063882 Maybridge3_000705 OC(C(=O)O)c1cccc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A02 compound treatment 0.306 -0.0101 -0.81 0.308 -0.0111 -1.01 -1.2876 -0.994 1012545 Maybridge3_000706 O=C(c1ccccc1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A03 compound treatment 0.336 0.0199 1.61 0.327 0.00787 0.71 1.6402 0.9334 1340150 Maybridge3_000707 CC(=O)Nc1ccc(O)c(c1)C(=O)CC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A04 compound treatment 0.302 -0.0141 -1.13 0.308 -0.0111 -1.01 -1.5153 -0.9984 2075533 Maybridge3_000708 O=C(CC1S/C(=N/c2ccccc2)/NC1=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A05 compound treatment 0.31 -0.00606 -0.49 0.319 -1.33E-4 -0.01 -0.3538 -0.7244 1587589 Maybridge3_000709 O=C(C1CCCCC1)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A06 compound treatment 0.418 0.102 8.21 0.411 0.0919 8.34 11.7009 1.0 2075534 Maybridge3_000710 O=C/1Nc2ccccc2\C1=C/c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A07 compound treatment 0.307 -0.00906 -0.73 0.3 -0.0191 -1.74 -1.7441 -0.9258 1198441 Maybridge3_000711 COc1ccc(CCNC(=O)c2cccs2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A08 compound treatment 0.301 -0.0151 -1.21 0.297 -0.0221 -2.01 -2.2783 -0.9708 1664899 Maybridge3_000712 Cc1cc(C)c(C(=O)O)c2CC(C)(C)C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A09 compound treatment 0.298 -0.0181 -1.45 0.3 -0.0191 -1.74 -2.2566 -0.9961 1156182 Maybridge3_000713 CN1C2CCC1CC(C2)NC(=O)CSc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A10 compound treatment 0.301 -0.0151 -1.21 0.297 -0.0221 -2.01 -2.2783 -0.9708 1579963 Maybridge3_000714 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A11 compound treatment 0.434 0.118 9.5 0.432 0.113 10.25 13.9598 0.9993 1650341 Maybridge3_000715 CCOC(=O)c1cc(=O)oc2cc(O)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A12 compound treatment 0.337 0.0209 1.69 0.336 0.0169 1.53 2.2748 0.9988 2075535 Maybridge3_000716 CN(C)c1ccc(cc1)C2Nc3ccccc3S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A13 compound treatment 0.307 -0.00906 -0.73 0.308 -0.0111 -1.01 -1.2306 -0.9872 1654309 Maybridge3_000717 CC1(CC2(C)CC3(C)C1)CC(CCO)(C2)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A14 compound treatment 0.297 -0.0191 -1.54 0.304 -0.0151 -1.37 -2.0568 -0.9985 1563478 Maybridge3_000718 OC(=O)CCC(=O)N1CCCc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A15 compound treatment 0.345 0.0289 2.33 0.357 0.0379 3.44 4.0782 0.9821 1663621 Maybridge3_000719 CCOC(=O)c1nnc2cc(sc2n1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A16 compound treatment 0.299 -0.0171 -1.37 0.301 -0.0181 -1.65 -2.1354 -0.996 2075536 Maybridge3_000720 COc1ccc(OC)c(c1)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A17 compound treatment 0.31 -0.00606 -0.49 0.312 -0.00713 -0.65 -0.8031 -0.9903 2075537 Maybridge3_000721 CCCOc1cccc(c1)C2CCCCN(C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A18 compound treatment 0.3 -0.0161 -1.29 0.302 -0.0171 -1.56 -2.0143 -0.9958 2075538 Maybridge3_000722 Clc1ccc(cc1)c2noc(CSC3=NCC4CCCC4N3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A19 compound treatment 0.302 -0.0141 -1.13 0.315 -0.00413 -0.38 -1.066 -0.8936 1715439 Maybridge3_000723 CN(CC(=O)Nc1ccccc1)C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A20 compound treatment 0.3 -0.0161 -1.29 0.302 -0.0171 -1.56 -2.0143 -0.9958 1056263 Maybridge3_000724 COc1ccc(cc1)C2C(C#N)(C#N)C2(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A21 compound treatment 0.301 -0.0151 -1.21 0.304 -0.0151 -1.37 -1.829 -0.9981 1297522 Maybridge3_000725 OC(=O)C1C(C2CCC1CCC2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A22 compound treatment 0.302 -0.0141 -1.13 0.306 -0.0131 -1.19 -1.6437 -0.9997 1429927 Maybridge3_000726 Clc1ccc(cc1)c2nc(CN3CCOCC3)cs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A23 mock treatment 0.298 -0.0181 -1.45 0.297 -0.0221 -2.01 -2.4491 -0.9874 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 A24 positive control 0.081 -0.235 -18.93 0.081 -0.238 -21.62 -28.6693 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B01 compound treatment 0.33 0.0139 1.12 0.334 0.0149 1.35 1.7478 0.9958 1652436 Maybridge3_000727 Oc1nc(CSc2ccccn2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B02 compound treatment 0.332 0.0159 1.28 0.338 0.0189 1.71 2.1185 0.9899 1168234 Maybridge3_000728 Clc1ccc(C(=O)N(CC#N)CC#N)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B03 compound treatment 0.329 0.0129 1.04 0.329 0.00987 0.9 1.37 0.9972 2075539 Maybridge3_000729 CC(OC(=O)Nc1c(C)onc1c2ccccc2Cl)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B04 compound treatment 0.331 0.0149 1.2 0.337 0.0179 1.62 1.9973 0.9892 2075540 Maybridge3_000730 On1c(cc(cc1=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B05 compound treatment 0.338 0.0219 1.77 0.331 0.0119 1.08 2.0108 0.9718 2075541 Maybridge3_000731 CSC1=C(C#N)C(=O)NC(S1)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B06 compound treatment 0.321 0.00494 0.4 0.326 0.00687 0.62 0.7219 0.9764 2075542 Maybridge3_000732 CS(=O)(=O)NC(=N)c1ccncc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B07 compound treatment 0.332 0.0159 1.28 0.342 0.0229 2.08 2.3752 0.9733 2075543 Maybridge3_000733 FC(F)(F)c1cc(C#CCN2CCOCC2)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B08 compound treatment 0.325 0.00894 0.72 0.328 0.00887 0.8 1.078 0.9984 1537560 Maybridge3_000734 CC1CN(CC(C)O1)c2ccc(N)cc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B09 compound treatment 0.323 0.00694 0.56 0.329 0.00987 0.9 1.0283 0.9742 2075544 Maybridge3_000735 Oc1ccccc1C2NC(=NO2)CC(=O)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B10 compound treatment 0.32 0.00394 0.32 0.328 0.00887 0.8 0.7933 0.9171 1599729 Maybridge3_000736 CC(=O)NCc1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B11 compound treatment 0.307 -0.00906 -0.73 0.316 -0.00313 -0.28 -0.7171 -0.9156 2075545 Maybridge3_000737 Clc1ccc(SCc2ccc(o2)C(=O)Nc3cccnc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B12 compound treatment 0.311 -0.00506 -0.41 0.321 0.00187 0.17 -0.1685 -0.3816 2075546 Maybridge3_000738 COc1ccc(OC(=O)c2c(Cl)cccc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B13 compound treatment 0.362 0.0459 3.7 0.362 0.0429 3.89 5.3671 0.9997 2075547 Maybridge3_000739 NC1=C(C#N)C(C(=C(O1)c2ccco2)C#N)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B14 compound treatment 0.325 0.00894 0.72 0.326 0.00687 0.62 0.9496 0.9974 1638414 Maybridge3_000740 CC1CN(CC(C)O1)C(=O)CCCC(=O)N2CC(C)OC(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B15 compound treatment 0.321 0.00494 0.4 0.329 0.00987 0.9 0.9144 0.9332 2075548 Maybridge3_000741 COc1ccc(OC(=O)c2snnc2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B16 compound treatment 0.403 0.0869 7.0 0.403 0.0839 7.61 10.3333 0.9991 2075549 Maybridge3_000742 Nc1ccccc1SC(CC(=O)c2cccs2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B17 compound treatment 0.325 0.00894 0.72 0.324 0.00487 0.44 0.8213 0.9725 2075550 Maybridge3_000743 Cc1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B18 compound treatment 0.32 0.00394 0.32 0.332 0.0129 1.17 1.0501 0.8677 2075551 Maybridge3_000744 Oc1ccccc1/C=N/c2n[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B19 compound treatment 0.322 0.00594 0.48 0.333 0.0139 1.26 1.2281 0.9121 2075552 Maybridge3_000745 Clc1ccc(CNc2cccc(Cl)c2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B20 compound treatment 0.318 0.00194 0.16 0.328 0.00887 0.8 0.6794 0.8288 2075553 Maybridge3_000746 Clc1cccc(Cl)c1CSC(=S)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B21 compound treatment 0.325 0.00894 0.72 0.332 0.0129 1.17 1.3348 0.9729 2075554 Maybridge3_000747 CN(C)c1ccc(/C=N/O)c(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B22 compound treatment 0.321 0.00494 0.4 0.324 0.00487 0.44 0.5935 0.9986 2075555 Maybridge3_000748 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B23 mock treatment 0.317 9.37E-4 0.08 0.325 0.00587 0.53 0.4299 0.7994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 B24 positive control 0.08 -0.236 -19.01 0.081 -0.238 -21.62 -28.7262 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C01 compound treatment 0.319 0.00294 0.24 0.324 0.00487 0.44 0.4796 0.9572 1260995 Maybridge3_000749 O=C(c1ccccc1)c2ccc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C02 compound treatment 0.316 -6.25E-5 -0.01 0.335 0.0159 1.44 1.0148 0.7046 2075556 Maybridge3_000750 Brc1ccc2NC(=O)/C(=C\C(=O)c3ccc4OCOc4c3)/c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C03 compound treatment 0.319 0.00294 0.24 0.317 -0.00213 -0.19 0.0303 0.0992 1154181 Maybridge3_000751 O=C(C1CCCCC1)N2CCN(CC2)c3ncccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C04 compound treatment 0.313 -0.00306 -0.25 0.316 -0.00313 -0.28 -0.3755 -0.9975 2075557 Maybridge3_000752 Brc1ccc(CS(=N)Nc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C05 compound treatment 0.308 -0.00806 -0.65 0.318 -0.00113 -0.1 -0.5318 -0.8091 1714598 Maybridge3_000753 COC(=O)c1ccccc1S(=O)(=O)NC2C(C)(C)C3CCC2(C)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C06 compound treatment 0.379 0.0629 5.07 0.404 0.0849 7.7 9.0309 0.9794 617 Maybridge3_000754 COc1cc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C07 compound treatment 0.31 -0.00606 -0.49 0.314 -0.00513 -0.47 -0.6747 -0.9997 1286190 Maybridge3_000755 COc1ccccc1N2CCN(Cc3cccc4ccccc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C08 compound treatment 0.312 -0.00406 -0.33 0.328 0.00887 0.8 0.3378 0.3888 2075558 Maybridge3_000756 NS(=O)(=O)/C=C/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C09 compound treatment 0.305 -0.0111 -0.89 0.312 -0.00713 -0.65 -1.0878 -0.9877 1255945 Maybridge3_000757 COc1ccc(CSCC(=O)NC2CC3CCC(C2)N3C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C10 compound treatment 0.306 -0.0101 -0.81 0.323 0.00387 0.35 -0.3248 -0.3678 1614043 Maybridge3_000758 Clc1c(NC(=O)c2ccccc2C(=O)NCc3cccnc3)sc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C11 compound treatment 0.308 -0.00806 -0.65 0.32 8.67E-4 0.08 -0.4035 -0.6169 1053995 Maybridge3_000759 N#Cc1ccccc1c2ccccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C12 compound treatment 0.305 -0.0111 -0.89 0.314 -0.00513 -0.47 -0.9594 -0.9543 1252316 Maybridge3_000760 COc1cccc(C2Nc3ccccc3S2)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C13 compound treatment 0.313 -0.00306 -0.25 0.317 -0.00213 -0.19 -0.3113 -0.9928 2075559 Maybridge3_000761 CSC(=S)OCC1(CC2CC3CC(C2)C1)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C14 compound treatment 0.309 -0.00706 -0.57 0.323 0.00387 0.35 -0.154 -0.2304 1195010 Maybridge3_000762 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C15 compound treatment 0.319 0.00294 0.24 0.32 8.67E-4 0.08 0.2229 0.8941 1557640 Maybridge3_000763 OCC1CN(Cc2ccccc2)C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C16 compound treatment 0.319 0.00294 0.24 0.336 0.0169 1.53 1.2499 0.8068 2075560 Maybridge3_000764 Cc1c(C)c(C)c(CSc2nnc(CC#N)n2C)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C17 compound treatment 0.323 0.00694 0.56 0.322 0.00287 0.26 0.579 0.9395 2075561 Maybridge3_000765 CS(=O)(=O)c1ncc(OCc2ccccc2)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C18 compound treatment 0.307 -0.00906 -0.73 0.322 0.00287 0.26 -0.332 -0.4285 2075562 Maybridge3_000766 Clc1ccc(cc1)c2noc(CSc3ccccn3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C19 compound treatment 0.324 0.00794 0.64 0.318 -0.00113 -0.1 0.3792 0.5858 1011473 Maybridge3_000767 NC(=O)C1CCCCC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C20 compound treatment 0.313 -0.00306 -0.25 0.329 0.00987 0.9 0.4589 0.494 1503216 Maybridge3_000768 COc1ccc(cc1)C(CC(=O)N)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C21 compound treatment 0.321 0.00494 0.4 0.321 0.00187 0.17 0.401 0.9277 2075563 Maybridge3_000769 C/C(=N\O)/C(=O)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C22 compound treatment 0.299 -0.0171 -1.37 0.314 -0.00513 -0.47 -1.301 -0.8967 2075564 Maybridge3_000770 Clc1ccc(cc1)c2nc(CSc3ccccn3)cs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C23 mock treatment 0.312 -0.00406 -0.33 0.309 -0.0101 -0.92 -0.8817 -0.9032 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 C24 positive control 0.083 -0.233 -18.77 0.083 -0.236 -21.43 -28.427 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D01 compound treatment 0.333 0.0169 1.36 0.333 0.0139 1.26 1.8545 0.9992 2075565 Maybridge3_000771 Oc1ccccc1/C=N/c2nc(cs2)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D02 compound treatment 0.333 0.0169 1.36 0.342 0.0229 2.08 2.4321 0.9793 2075566 Maybridge3_000772 CN(C)C(=S)SCc1ccc(cc1)C(=O)Oc2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D03 compound treatment 0.31 -0.00606 -0.49 0.323 0.00387 0.35 -0.097 -0.1614 2075567 Maybridge3_000773 COC(=S)Nc1ccc(cc1)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D04 compound treatment 0.32 0.00394 0.32 0.327 0.00787 0.71 0.7291 0.9332 2075568 Maybridge3_000774 Cc1nnsc1C(=O)NCCc2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D05 compound treatment 0.321 0.00494 0.4 0.334 0.0149 1.35 1.2354 0.8781 2075569 Maybridge3_000775 Cc1ncc(CSc2ccccn2)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D06 compound treatment 0.325 0.00894 0.72 0.328 0.00887 0.8 1.078 0.9984 1137680 Maybridge3_000776 CCN(CCC#N)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D07 compound treatment 0.325 0.00894 0.72 0.33 0.0109 0.99 1.2064 0.988 1309582 Maybridge3_000777 Fc1cccc(F)c1C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D08 compound treatment 0.327 0.0109 0.88 0.329 0.00987 0.9 1.2561 1.0 1686550 Maybridge3_000778 Cc1onc(c1C(=O)NCCO)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D09 compound treatment 0.324 0.00794 0.64 0.329 0.00987 0.9 1.0853 0.9863 2075570 Maybridge3_000779 COc1cc(Cl)c(cc1NC(=O)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D10 compound treatment 0.332 0.0159 1.28 0.339 0.0199 1.8 2.1826 0.9861 2075571 Maybridge3_000780 CCN(CC)C(=S)Oc1ccc(Br)cc1C(=O)NCCc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D11 compound treatment 0.343 0.0269 2.17 0.342 0.0229 2.08 3.0015 0.9998 2075572 Maybridge3_000781 Clc1ccc(SCc2ccc(o2)C(=O)N3CCOCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D12 compound treatment 0.321 0.00494 0.4 0.324 0.00487 0.44 0.5935 0.9986 2075573 Maybridge3_000782 Fc1cccc(NCCCn2ccnc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D13 compound treatment 0.363 0.0469 3.78 0.342 0.0229 2.08 4.1404 0.9602 2075574 Maybridge3_000783 CS/C(=C(/C#N)\C(=O)c1ccco1)/Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D14 compound treatment 0.325 0.00894 0.72 0.341 0.0219 1.98 1.9124 0.9058 1563197 Maybridge3_000784 O=C(CCCC(=O)N1CCCC1)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D15 compound treatment 0.321 0.00494 0.4 0.329 0.00987 0.9 0.9144 0.9332 1593642 Maybridge3_000785 Cc1nnsc1C(=O)Oc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D16 compound treatment 0.322 0.00594 0.48 0.327 0.00787 0.71 0.843 0.981 2075575 Maybridge3_000786 CC(=O)NCCc1c(F)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D17 compound treatment 0.402 0.0859 6.92 0.41 0.0909 8.25 10.7256 0.9962 2075576 Maybridge3_000787 Cc1csc(n1)c2snnc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D18 compound treatment 0.321 0.00494 0.4 0.333 0.0139 1.26 1.1712 0.8873 2075577 Maybridge3_000788 CCOC(=O)NCCc1c(F)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D19 compound treatment 0.324 0.00794 0.64 0.328 0.00887 0.8 1.0211 0.9935 2075578 Maybridge3_000789 OC1(CC1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D20 compound treatment 0.342 0.0259 2.09 0.338 0.0189 1.71 2.6879 0.9951 1315234 Maybridge3_000790 Clc1cc(CSC(=S)N2CCSCC2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D21 compound treatment 0.315 -0.00106 -0.09 0.328 0.00887 0.8 0.5086 0.6284 2075579 Maybridge3_000791 CCc1nc(cs1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D22 compound treatment 0.319 0.00294 0.24 0.321 0.00187 0.17 0.2871 0.9866 1677375 Maybridge3_000792 NS(=O)(=O)c1ccccc1Oc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D23 mock treatment 0.312 -0.00406 -0.33 0.321 0.00187 0.17 -0.1115 -0.3027 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 D24 positive control 0.084 -0.232 -18.69 0.084 -0.235 -21.34 -28.3059 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E01 compound treatment 0.361 0.0449 3.62 0.362 0.0429 3.89 5.3102 0.9993 1451192 Maybridge3_000793 COC(=O)C1C2C=CCC2=C(C(=O)OC)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E02 compound treatment 0.341 0.0249 2.01 0.352 0.0329 2.98 3.5295 0.9814 2075580 Maybridge3_000794 O=C1/C(=C/c2cccc3ccccc23)/Nc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E03 compound treatment 0.322 0.00594 0.48 0.33 0.0109 0.99 1.0356 0.9447 2075581 Maybridge3_000795 FC(F)(F)c1cccc(c1)C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E04 compound treatment 0.317 9.37E-4 0.08 0.322 0.00287 0.26 0.2374 0.8761 2075582 Maybridge3_000796 N=C(Nc1ccccc1)SCc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E05 compound treatment 0.317 9.37E-4 0.08 0.326 0.00687 0.62 0.4941 0.787 1607133 Maybridge3_000797 CC1(C)C(NC(=O)C2CCC2)C3(C)CCC1C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E06 compound treatment 0.362 0.0459 3.7 0.363 0.0439 3.98 5.4313 0.9993 2075583 Maybridge3_000798 COc1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E07 compound treatment 0.321 0.00494 0.4 0.336 0.0169 1.53 1.3637 0.8621 1297748 Maybridge3_000799 Nc1ccc(cc1)C(=O)Oc2ccc(Oc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E08 compound treatment 0.337 0.0209 1.69 0.347 0.0279 2.53 2.9808 0.9806 2075584 Maybridge3_000800 COc1cc(cc(OC)c1OC)C2SC(=C(C#N)C(=N2)O)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E09 compound treatment 0.32 0.00394 0.32 0.33 0.0109 0.99 0.9217 0.8896 1614928 Maybridge3_000801 CN1C2CCC1CC(C2)NC(=O)CSc3nnc(N)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E10 compound treatment 0.322 0.00594 0.48 0.33 0.0109 0.99 1.0356 0.9447 1586400 Maybridge3_000802 O=C(Nc1ccccc1C(=O)NCc2cccnc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E11 compound treatment 0.33 0.0139 1.12 0.327 0.00787 0.71 1.2985 0.9762 2075585 Maybridge3_000803 COC(=O)NC1(CCCC2CCC1)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E12 compound treatment 0.317 9.37E-4 0.08 0.325 0.00587 0.53 0.4299 0.7994 2075586 Maybridge3_000804 Cc1ccc(NC(=O)CSCc2ccc(C#N)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E13 compound treatment 0.328 0.0119 0.96 0.324 0.00487 0.44 0.9921 0.9378 1644876 Maybridge3_000805 CCC1(CC2CC3(C1)NC(=O)C)CC(C2)(C3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E14 compound treatment 0.31 -0.00606 -0.49 0.331 0.0119 1.08 0.4165 0.3521 1374505 Maybridge3_000806 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E15 compound treatment 0.327 0.0109 0.88 0.33 0.0109 0.99 1.3203 0.9984 2075587 Maybridge3_000807 CC(C)(C)N1CC(CO)OC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E16 compound treatment 0.316 -6.25E-5 -0.01 0.335 0.0159 1.44 1.0148 0.7046 2075588 Maybridge3_000808 N/C(=N\O)/c1ccc2OCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E17 compound treatment 0.32 0.00394 0.32 0.332 0.0129 1.17 1.0501 0.8677 1054635 Maybridge3_000809 CSc1ncc(OCc2ccccc2)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E18 compound treatment 0.335 0.0189 1.52 0.333 0.0139 1.26 1.9684 0.9955 2075589 Maybridge3_000810 CC(=O)OCc1c(C)c(C)c(C)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E19 compound treatment 0.317 9.37E-4 0.08 0.324 0.00487 0.44 0.3657 0.8161 2075590 Maybridge3_000811 CC1CC(C(CC1C)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E20 compound treatment 0.321 0.00494 0.4 0.331 0.0119 1.08 1.0428 0.9082 1390420 Maybridge3_000812 Cc1cc(C)c(C(=O)N)c(CC(C)(C)C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E21 compound treatment 0.326 0.00994 0.8 0.331 0.0119 1.08 1.3275 0.9893 2075591 Maybridge3_000813 COC(=O)C(=C(C)C)c1ccc(cc1)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E22 compound treatment 0.316 -6.25E-5 -0.01 0.321 0.00187 0.17 0.1163 0.6858 2075592 Maybridge3_000814 CSc1nc2ccccc2n3cccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E23 mock treatment 0.313 -0.00306 -0.25 0.316 -0.00313 -0.28 -0.3755 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 E24 positive control 0.086 -0.23 -18.53 0.086 -0.233 -21.16 -28.0636 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F01 compound treatment 0.329 0.0129 1.04 0.333 0.0139 1.26 1.6267 0.9956 2075593 Maybridge3_000815 FC(F)(F)c1cccc(c1)/C(=C/c2cccnc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F02 compound treatment 0.323 0.00694 0.56 0.329 0.00987 0.9 1.0283 0.9742 2075594 Maybridge3_000816 Clc1ccc(C(=O)NCc2cccs2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F03 compound treatment 0.329 0.0129 1.04 0.334 0.0149 1.35 1.6909 0.9918 2075595 Maybridge3_000817 Fc1cccc(F)c1C(=O)NCCCn2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F04 compound treatment 0.321 0.00494 0.4 0.335 0.0159 1.44 1.2995 0.8698 2075596 Maybridge3_000818 Cc1onc(c1CC#N)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F05 compound treatment 0.338 0.0219 1.77 0.329 0.00987 0.9 1.8824 0.9504 1042708 Maybridge3_000819 Cc1ncc(CSc2ccc(Cl)cc2)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F06 compound treatment 0.322 0.00594 0.48 0.326 0.00687 0.62 0.7788 0.9914 1132871 Maybridge3_000820 Oc1ccccc1C(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F07 compound treatment 0.323 0.00694 0.56 0.33 0.0109 0.99 1.0925 0.9638 2075597 Maybridge3_000821 Fc1cccc(F)c1CN2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F08 compound treatment 0.326 0.00994 0.8 0.335 0.0159 1.44 1.5843 0.9615 2075598 Maybridge3_000822 Cc1snc(c1C(=O)O)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F09 compound treatment 0.317 9.37E-4 0.08 0.333 0.0139 1.26 0.9434 0.7482 2075599 Maybridge3_000823 NC(=O)c1nnn(c1c2ccccc2)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F10 compound treatment 0.336 0.0199 1.61 0.34 0.0209 1.89 2.4746 0.9966 1691543 Maybridge3_000824 Clc1cccc(Oc2ccc(cc2)S(=O)(=O)N3CCOCC3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F11 compound treatment 0.324 0.00794 0.64 0.333 0.0139 1.26 1.342 0.9506 1296871 Maybridge3_000825 CN(C)c1c(F)cc(cc1F)c2nnn[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F12 compound treatment 0.323 0.00694 0.56 0.344 0.0249 2.26 1.9911 0.8563 2075600 Maybridge3_000826 Fc1ccc(N/C=N/c2ccc(F)cc2F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F13 compound treatment 0.33 0.0139 1.12 0.345 0.0259 2.35 2.4539 0.9429 1531556 Maybridge3_000827 COc1cccc(Oc2ccc(OC)cc2C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F14 compound treatment 0.338 0.0219 1.77 0.36 0.0409 3.71 3.8722 0.9424 2075601 Maybridge3_000828 CC(C)(C)NC1=C(C#N)C(=O)NC(S1)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F15 compound treatment 0.322 0.00594 0.48 0.353 0.0339 3.07 2.5118 0.8074 2075602 Maybridge3_000829 Clc1ccc(OC(=O)c2snnc2c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F16 compound treatment 0.325 0.00894 0.72 0.345 0.0259 2.35 2.1692 0.8833 1384617 Maybridge3_000830 Clc1ccc(cc1Cl)S(=O)(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F17 compound treatment 0.326 0.00994 0.8 0.327 0.00787 0.71 1.0708 0.9984 2075603 Maybridge3_000831 CCOC(=O)Nc1c(C)noc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F18 compound treatment 0.327 0.0109 0.88 0.336 0.0169 1.53 1.7054 0.9655 2075604 Maybridge3_000832 CCOC(=O)Nc1nc2cc(C)ccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F19 compound treatment 0.324 0.00794 0.64 0.329 0.00987 0.9 1.0853 0.9863 1342849 Maybridge3_000833 Fc1cccc(Cl)c1CNCc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F20 compound treatment 0.325 0.00894 0.72 0.33 0.0109 0.99 1.2064 0.988 2075605 Maybridge3_000834 Oc1cc(CSC(=S)N2CCSCC2)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F21 compound treatment 0.32 0.00394 0.32 0.329 0.00987 0.9 0.8575 0.9026 2075606 Maybridge3_000835 C(c1cccs1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F22 compound treatment 0.328 0.0119 0.96 0.335 0.0159 1.44 1.6981 0.9807 1167965 Maybridge3_000836 Clc1ccc(Oc2ccccc2S(=O)(=O)N3CCOCC3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F23 mock treatment 0.318 0.00194 0.16 0.316 -0.00313 -0.28 -0.0908 -0.2799 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 F24 positive control 0.086 -0.23 -18.53 0.085 -0.234 -21.25 -28.1278 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G01 compound treatment 0.104 -0.212 -17.08 0.103 -0.216 -19.62 -25.9476 -0.9976 1004045 Maybridge3_000837 COC1=CC(=O)C(=CC1=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G02 compound treatment 0.321 0.00494 0.4 0.325 0.00587 0.53 0.6577 0.9896 2075607 Maybridge3_000838 FC(F)(F)c1cccc(Nc2nnc(s2)c3cccnc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G03 compound treatment 0.321 0.00494 0.4 0.322 0.00287 0.26 0.4651 0.9789 1649197 Maybridge3_000839 O=C(N1CCN(CC1)c2cccc3[nH]ccc23)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G04 compound treatment 0.32 0.00394 0.32 0.328 0.00887 0.8 0.7933 0.9171 2075608 Maybridge3_000840 NC(=N)SCc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G05 compound treatment 0.321 0.00494 0.4 0.338 0.0189 1.71 1.4921 0.8487 1527173 Maybridge3_000841 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G06 compound treatment 0.324 0.00794 0.64 0.35 0.0309 2.8 2.4331 0.8467 2075609 Maybridge3_000842 O=C/1Nc2ccccc2\C1=C/c3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G07 compound treatment 0.317 9.37E-4 0.08 0.335 0.0159 1.44 1.0718 0.7432 1433728 Maybridge3_000843 O=C(OC1CN2CCC1CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G08 compound treatment 0.316 -6.25E-5 -0.01 0.334 0.0149 1.35 0.9507 0.7045 2075610 Maybridge3_000844 CSC1=C(C#N)C(=O)NC(S1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G09 compound treatment 0.297 -0.0191 -1.54 0.303 -0.0161 -1.46 -2.121 -0.9997 1032294 Maybridge3_000845 CN(C)N=Nc1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G10 compound treatment 0.33 0.0139 1.12 0.354 0.0349 3.16 3.0315 0.9028 2075611 Maybridge3_000846 O=C(CSc1nnc(SCC(=O)c2ccccc2)s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G11 compound treatment 0.321 0.00494 0.4 0.333 0.0139 1.26 1.1712 0.8873 2075612 Maybridge3_000847 C/C(=N/O)/C1(CCC2CC1)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G12 compound treatment 0.314 -0.00206 -0.17 0.329 0.00987 0.9 0.5159 0.5663 1578875 Maybridge3_000848 COc1ccc(NC(=O)CSCC(=O)N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G13 compound treatment 0.319 0.00294 0.24 0.321 0.00187 0.17 0.2871 0.9866 2075613 Maybridge3_000849 CC1(CC2(C)CC3(C)C1)CC(CO)(C2)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G14 compound treatment 0.083 -0.233 -18.77 0.095 -0.224 -20.34 -27.6568 -0.9992 2075614 Maybridge3_000850 COc1cc(OC)c(cc1Cl)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G15 compound treatment 0.317 9.37E-4 0.08 0.324 0.00487 0.44 0.3657 0.8161 1709987 Maybridge3_000851 Cc1ccc(OCC2CN(Cc3ccccc3)C(=O)O2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G16 compound treatment 0.318 0.00194 0.16 0.324 0.00487 0.44 0.4227 0.9022 1165784 Maybridge3_000852 CCOC(=O)C(Cc1c(C)c(C)c(C)c(C)c1C)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G17 compound treatment 0.323 0.00694 0.56 0.338 0.0189 1.71 1.606 0.8915 1054634 Maybridge3_000853 Nc1ncc(OCc2ccccc2)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G18 compound treatment 0.328 0.0119 0.96 0.337 0.0179 1.62 1.8265 0.9688 1392212 Maybridge3_000854 Clc1ccc(cc1)c2noc(CN3CCOCC3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G19 compound treatment 0.325 0.00894 0.72 0.325 0.00587 0.53 0.8855 0.989 2075615 Maybridge3_000855 O/N=C(\CN1CCCCC1)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G20 compound treatment 0.327 0.0109 0.88 0.332 0.0129 1.17 1.4486 0.9903 2075616 Maybridge3_000856 FC(F)(F)c1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G21 compound treatment 0.317 9.37E-4 0.08 0.323 0.00387 0.35 0.3016 0.84 2075617 Maybridge3_000857 C/C(=N\O)/C(=C)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G22 compound treatment 0.328 0.0119 0.96 0.334 0.0149 1.35 1.6339 0.9862 1617420 Maybridge3_000858 Cc1ccc-2c(NC(c3cccn32)c4ccc(cc4)C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G23 mock treatment 0.314 -0.00206 -0.17 0.318 -0.00113 -0.1 -0.1902 -0.9735 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 G24 positive control 0.087 -0.229 -18.45 0.086 -0.233 -21.16 -28.0067 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H01 compound treatment 0.329 0.0129 1.04 0.331 0.0119 1.08 1.4983 0.9999 2075618 Maybridge3_000859 CCOC(=O)C(C(Nc1ccc(F)cc1)c2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H02 compound treatment 0.312 -0.00406 -0.33 0.328 0.00887 0.8 0.3378 0.3888 2075619 Maybridge3_000860 CN(C)C(=S)SCc1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H03 compound treatment 0.319 0.00294 0.24 0.326 0.00687 0.62 0.608 0.912 2075620 Maybridge3_000861 COC(=S)Nc1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H04 compound treatment 0.326 0.00994 0.8 0.333 0.0139 1.26 1.4559 0.9761 2075621 Maybridge3_000862 Nc1cccc(F)c1C(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H05 compound treatment 0.331 0.0149 1.2 0.332 0.0129 1.17 1.6764 0.9999 1122553 Maybridge3_000863 Cc1ncc(CSc2ccccc2N)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H06 compound treatment 0.324 0.00794 0.64 0.331 0.0119 1.08 1.2136 0.9689 2075622 Maybridge3_000864 CC(=O)NCc1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H07 compound treatment 0.324 0.00794 0.64 0.333 0.0139 1.26 1.342 0.9506 1406262 Maybridge3_000865 Fc1cccc(F)c1C(=O)Nc2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H08 compound treatment 0.318 0.00194 0.16 0.321 0.00187 0.17 0.2301 0.9992 2075623 Maybridge3_000866 CC1(CO)CS/C(=N\c2ccc(F)cc2F)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H09 compound treatment 0.321 0.00494 0.4 0.319 -1.33E-4 -0.01 0.2726 0.6853 1240423 Maybridge3_000867 Fc1cccc(F)c1C(=O)Oc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H10 compound treatment 0.324 0.00794 0.64 0.332 0.0129 1.17 1.2778 0.9598 1428324 Maybridge3_000868 Clc1cc(Cl)cc(NC(=O)CCN2CCOCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H11 compound treatment 0.319 0.00294 0.24 0.319 -1.33E-4 -0.01 0.1587 0.6701 2075624 Maybridge3_000869 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2ccncc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H12 compound treatment 0.315 -0.00106 -0.09 0.325 0.00587 0.53 0.3161 0.586 2075625 Maybridge3_000870 Cc1nn(C)c(C)c1Cc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H13 compound treatment 0.336 0.0199 1.61 0.334 0.0149 1.35 2.0895 0.9963 1163257 Maybridge3_000871 Cc1onc(c1C(=O)N(CC=C)CC=C)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H14 compound treatment 0.405 0.0889 7.16 0.405 0.0859 7.79 10.5755 0.9991 2075626 Maybridge3_000872 O=C(/C=C/1\NC(=O)CS1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H15 compound treatment 0.327 0.0109 0.88 0.318 -0.00113 -0.1 0.55 0.6203 2075627 Maybridge3_000873 Cc1nnsc1C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H16 compound treatment 0.326 0.00994 0.8 0.325 0.00587 0.53 0.9424 0.9804 2075628 Maybridge3_000874 Cc1c(C)c(C)c(CN2CCSCC2)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H17 compound treatment 0.336 0.0199 1.61 0.33 0.0109 0.99 1.8327 0.9726 1289132 Maybridge3_000875 Fc1cccc(NCc2cccnc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H18 compound treatment 0.316 -6.25E-5 -0.01 0.335 0.0159 1.44 1.0148 0.7046 2075629 Maybridge3_000876 N#Cc1cnc(nc1c2cccs2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H19 compound treatment 0.322 0.00594 0.48 0.323 0.00387 0.35 0.5863 0.9884 2075630 Maybridge3_000877 CSc1nnc(s1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H20 compound treatment 0.313 -0.00306 -0.25 0.313 -0.00613 -0.56 -0.568 -0.9329 2075631 Maybridge3_000878 Cc1cc(cc(C)c1F)S(=O)(=O)Nc2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H21 compound treatment 0.319 0.00294 0.24 0.327 0.00787 0.71 0.6722 0.8936 2075632 Maybridge3_000879 CN(C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H22 compound treatment 0.33 0.0139 1.12 0.335 0.0159 1.44 1.812 0.9924 1470715 Maybridge3_000880 Cc1ncc(CSc2nc(cs2)C(C)(C)C)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H23 mock treatment 0.317 9.37E-4 0.08 0.326 0.00687 0.62 0.4941 0.787 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 H24 positive control 0.089 -0.227 -18.28 0.088 -0.231 -20.98 -27.7644 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I01 compound treatment 0.33 0.0139 1.12 0.331 0.0119 1.08 1.5553 0.9998 1627512 Maybridge3_000881 OC(C(O)C(=O)N1CCCC1)C(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I02 compound treatment 0.332 0.0159 1.28 0.341 0.0219 1.98 2.311 0.9777 1244598 Maybridge3_000882 NC(=O)c1cc(nc2ccc(Br)cc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I03 compound treatment 0.33 0.0139 1.12 0.338 0.0189 1.71 2.0046 0.979 1200031 Maybridge3_000883 O=C(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I04 compound treatment 0.313 -0.00306 -0.25 0.319 -1.33E-4 -0.01 -0.1829 -0.7409 2075633 Maybridge3_000884 N#CCSc1nsc(SCC#N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I05 compound treatment 0.325 0.00894 0.72 0.331 0.0119 1.08 1.2706 0.9808 1240063 Maybridge3_000885 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(NC(=O)C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I06 compound treatment 0.346 0.0299 2.41 0.354 0.0349 3.16 3.9426 0.991 2075634 Maybridge3_000886 Clc1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I07 compound treatment 0.321 0.00494 0.4 0.338 0.0189 1.71 1.4921 0.8487 1259827 Maybridge3_000887 COC(=O)c1c(O)c2ccccc2[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I08 compound treatment 0.328 0.0119 0.96 0.343 0.0239 2.17 2.2116 0.9331 2075635 Maybridge3_000888 CSC1=C(C#N)C(=O)NC(S1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I09 compound treatment 0.329 0.0129 1.04 0.327 0.00787 0.71 1.2416 0.983 2075636 Maybridge3_000889 CC1(C)C2CCC1(C)c3n[nH]c(c23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I10 compound treatment 0.32 0.00394 0.32 0.322 0.00287 0.26 0.4082 0.9952 1405984 Maybridge3_000890 Clc1ccc(cc1Cl)C(=O)Nc2ccccc2C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I11 compound treatment 0.322 0.00594 0.48 0.324 0.00487 0.44 0.6505 0.9992 2075637 Maybridge3_000891 C/C(=N/O)/C1(CCCC2CCC1)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I12 compound treatment 0.32 0.00394 0.32 0.316 -0.00313 -0.28 0.0231 0.0542 1604606 Maybridge3_000892 CCC(O)(c1ccccc1)c2ccccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I13 compound treatment 0.627 0.311 25.04 0.61 0.291 26.4 36.3743 0.9996 1343794 Maybridge3_000893 CCOC(=O)CSCN1CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I14 compound treatment 0.351 0.0349 2.81 0.349 0.0299 2.71 3.9064 0.9998 1420540 Maybridge3_000894 Cc1c(C)c(C)c(C(=O)CCCC(=O)O)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I15 compound treatment 0.32 0.00394 0.32 0.325 0.00587 0.53 0.6008 0.9693 2075638 Maybridge3_000895 CN(C)C(=O)COc1ccc2ccccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I16 compound treatment 0.325 0.00894 0.72 0.329 0.00987 0.9 1.1422 0.9941 2075639 Maybridge3_000896 O=C/1Nc2ccccc2\C1=C/C3CC4CC3C=C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I17 compound treatment 0.329 0.0129 1.04 0.323 0.00387 0.35 0.9849 0.8959 2075640 Maybridge3_000897 Cn1c2CCC(Cn3ccnc3)C(=O)c2c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I18 compound treatment 0.329 0.0129 1.04 0.331 0.0119 1.08 1.4983 0.9999 1457705 Maybridge3_000898 Clc1ccc(cc1)c2noc(CN3CCCC3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I19 compound treatment 0.328 0.0119 0.96 0.339 0.0199 1.8 1.9549 0.9566 1264910 Maybridge3_000899 COC(=O)c1ccc(NC(=O)C)c(c1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I20 compound treatment 0.329 0.0129 1.04 0.332 0.0129 1.17 1.5625 0.9984 2075641 Maybridge3_000900 FC(F)(F)c1cccc(CSC2=NCCCN2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I21 compound treatment 0.332 0.0159 1.28 0.33 0.0109 0.99 1.605 0.9915 1342131 Maybridge3_000901 CCOC(=O)C1(CCC(=NO)CC1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I22 compound treatment 0.325 0.00894 0.72 0.333 0.0139 1.26 1.3989 0.9648 2075642 Maybridge3_000902 Cc1ccnc(NC(=O)CSc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I23 mock treatment 0.321 0.00494 0.4 0.322 0.00287 0.26 0.4651 0.9789 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 I24 positive control 0.089 -0.227 -18.28 0.088 -0.231 -20.98 -27.7644 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J01 compound treatment 0.326 0.00994 0.8 0.329 0.00987 0.9 1.1991 0.9984 1694044 Maybridge3_000903 CCNc1cc(=N)n(CC)c2sc(C(=O)OCC)c(N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J02 compound treatment 0.327 0.0109 0.88 0.33 0.0109 0.99 1.3203 0.9984 2075643 Maybridge3_000904 CN(C)C(=S)SCc1nc(no1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J03 compound treatment 0.317 9.37E-4 0.08 0.317 -0.00213 -0.19 -0.0835 -0.402 2075644 Maybridge3_000905 COC(=S)Nc1ccc(Cl)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J04 compound treatment 0.327 0.0109 0.88 0.334 0.0149 1.35 1.577 0.9786 2075645 Maybridge3_000906 Cc1c(C)c(sc1C(=O)N)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J05 compound treatment 0.332 0.0159 1.28 0.336 0.0169 1.53 1.9901 0.9962 2075646 Maybridge3_000907 Cc1ncc(CSc2ccccc2/N=C/c3cc(Cl)cc(Cl)c3O)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J06 compound treatment 0.326 0.00994 0.8 0.334 0.0149 1.35 1.5201 0.9689 2075647 Maybridge3_000908 CC(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J07 compound treatment 0.325 0.00894 0.72 0.327 0.00787 0.71 1.0138 1.0 2075648 Maybridge3_000909 CSc1nc2c(C)c(C)c(C)c(C)c2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J08 compound treatment 0.331 0.0149 1.2 0.335 0.0159 1.44 1.869 0.996 1259138 Maybridge3_000910 CN(C)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J09 compound treatment 0.322 0.00594 0.48 0.323 0.00387 0.35 0.5863 0.9884 2075649 Maybridge3_000911 N/C(=N\O)/C=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J10 compound treatment 0.316 -6.25E-5 -0.01 0.319 -1.33E-4 -0.01 -0.0121 -0.9244 1484889 Maybridge3_000912 OC(COc1ccc(Cl)cc1Cl)Cn2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J11 compound treatment 0.32 0.00394 0.32 0.326 0.00687 0.62 0.6649 0.9509 2075650 Maybridge3_000913 C=C(CN1CCN(CC(=C)C#N)CC1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J12 compound treatment 0.314 -0.00206 -0.17 0.319 -1.33E-4 -0.01 -0.126 -0.7566 2075651 Maybridge3_000914 CSC1=C(C#N)C(=O)NC(S1)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J13 compound treatment 0.324 0.00794 0.64 0.322 0.00287 0.26 0.636 0.9215 2075652 Maybridge3_000915 CSc1ccc(Cl)cc1NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J14 compound treatment 0.32 0.00394 0.32 0.33 0.0109 0.99 0.9217 0.8896 2075653 Maybridge3_000916 O=C(/C=C/1\NC(=O)CS1)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J15 compound treatment 0.323 0.00694 0.56 0.317 -0.00213 -0.19 0.2581 0.4365 1172931 Maybridge3_000917 COc1ccc(cc1OC)S(=O)(=O)NCc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J16 compound treatment 0.321 0.00494 0.4 0.329 0.00987 0.9 0.9144 0.9332 2075654 Maybridge3_000918 Clc1cccc(N2CCSCC2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J17 compound treatment 0.326 0.00994 0.8 0.323 0.00387 0.35 0.814 0.9316 2075655 Maybridge3_000919 COC(=O)c1cccc(CS(=O)(=O)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J18 compound treatment 0.317 9.37E-4 0.08 0.319 -1.33E-4 -0.01 0.0448 0.5863 2075656 Maybridge3_000920 Cc1c(nnn1c2ccc(F)cc2F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J19 compound treatment 0.362 0.0459 3.7 0.364 0.0449 4.07 5.4955 0.9988 2075657 Maybridge3_000921 OC(=O)c1cc(NC(=O)/C=C/c2cccs2)ccc1N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J20 compound treatment 0.329 0.0129 1.04 0.328 0.00887 0.8 1.3058 0.9919 1413162 Maybridge3_000922 Clc1cccc(Cl)c1C(C#N)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J21 compound treatment 0.325 0.00894 0.72 0.332 0.0129 1.17 1.3348 0.9729 2075658 Maybridge3_000923 CS(=O)(=O)Cc1cc(Cl)cc2COCOc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J22 compound treatment 0.331 0.0149 1.2 0.339 0.0199 1.8 2.1257 0.9806 1613619 Maybridge3_000924 Cc1c(nnn1c2ccccc2Oc3ccc(Cl)cc3Cl)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J23 mock treatment 0.316 -6.25E-5 -0.01 0.32 8.67E-4 0.08 0.0521 0.6605 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 J24 positive control 0.09 -0.226 -18.2 0.088 -0.231 -20.98 -27.7075 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K01 compound treatment 0.327 0.0109 0.88 0.326 0.00687 0.62 1.0635 0.9857 2075659 Maybridge3_000925 Cn1c(nc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K02 compound treatment 0.323 0.00694 0.56 0.331 0.0119 1.08 1.1567 0.9533 2075660 Maybridge3_000926 Cc1c(C)c(C)c(CC#N)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K03 compound treatment 0.322 0.00594 0.48 0.329 0.00987 0.9 0.9714 0.9568 1360936 Maybridge3_000927 Clc1cccc(Cl)c1C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K04 compound treatment 0.315 -0.00106 -0.09 0.323 0.00387 0.35 0.1877 0.5195 2075661 Maybridge3_000928 Cc1ncc(s1)c2ccc3ccccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K05 compound treatment 0.325 0.00894 0.72 0.328 0.00887 0.8 1.078 0.9984 1458921 Maybridge3_000929 COc1ccccc1N2CCN(Cc3ccc(Cl)cc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K06 compound treatment 0.41 0.0939 7.56 0.433 0.114 10.34 12.6574 0.9882 2075662 Maybridge3_000930 O=C/1Nc2ccccc2\C1=C/c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K07 compound treatment 0.301 -0.0151 -1.21 0.325 0.00587 0.53 -0.4811 -0.3632 1675252 Maybridge3_000931 CCC(C)c1ccc(NC(=O)CSc2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K08 compound treatment 0.346 0.0299 2.41 0.366 0.0469 4.25 4.7128 0.9638 1645450 Maybridge3_000932 NC(=O)c1c(N)c(sc1SCc2ccccc2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K09 compound treatment 0.317 9.37E-4 0.08 0.324 0.00487 0.44 0.3657 0.8161 1015371 Maybridge3_000933 COc1c(CO)cc(C)cc1CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K10 compound treatment 0.334 0.0179 1.44 0.346 0.0269 2.44 2.7458 0.9687 2075663 Maybridge3_000934 N1C(c2cccn2-c3ccccc13)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K11 compound treatment 0.33 0.0139 1.12 0.329 0.00987 0.9 1.4269 0.9937 1922165 Maybridge3_000935 CC1(CC(=O)O1)C2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K12 compound treatment 0.32 0.00394 0.32 0.32 8.67E-4 0.08 0.2798 0.8566 2075664 Maybridge3_000936 Nc1ccccc1C(O)(Cc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K13 compound treatment 0.326 0.00994 0.8 0.334 0.0149 1.35 1.5201 0.9689 2075665 Maybridge3_000937 FC(F)(F)c1cc([nH]n1)c2ccc(cc2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K14 compound treatment 0.345 0.0289 2.33 0.349 0.0299 2.71 3.5647 0.9972 1667855 Maybridge3_000938 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)N3CCOCC3)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K15 compound treatment 0.319 0.00294 0.24 0.328 0.00887 0.8 0.7364 0.8778 1010990 Maybridge3_000939 OC(C(=O)OCc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K16 compound treatment 0.318 0.00194 0.16 0.332 0.0129 1.17 0.9362 0.7945 2075666 Maybridge3_000940 COc1ccc(cc1CN2CCCC2)/C(=N/O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K17 compound treatment 0.326 0.00994 0.8 0.327 0.00787 0.71 1.0708 0.9984 2075667 Maybridge3_000941 C/C(=N\O)/c1nnn(c1C)c2cc(ccc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K18 compound treatment 0.358 0.0419 3.38 0.355 0.0359 3.26 4.6901 0.9998 1618782 Maybridge3_000942 CCOC(=O)C1CCN(Cc2nc(no2)c3ccc(Cl)cc3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K19 compound treatment 0.328 0.0119 0.96 0.328 0.00887 0.8 1.2488 0.9961 1474567 Maybridge3_000943 O=C(NC1CC2CCC1CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K20 compound treatment 0.325 0.00894 0.72 0.326 0.00687 0.62 0.9496 0.9974 1733607 Maybridge3_000944 Cc1cc(C)c(C(=O)Nc2ccccc2)c(CC(C)(C)C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K21 compound treatment 0.324 0.00794 0.64 0.328 0.00887 0.8 1.0211 0.9935 1193355 Maybridge3_000945 COc1ccc(cc1)C2(CC3CC4CC(O)(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K22 compound treatment 0.324 0.00794 0.64 0.332 0.0129 1.17 1.2778 0.9598 1565286 Maybridge3_000946 Oc1nc(CN2CCOCC2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K23 mock treatment 0.316 -6.25E-5 -0.01 0.317 -0.00213 -0.19 -0.1405 -0.7252 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 K24 positive control 0.091 -0.225 -18.12 0.088 -0.231 -20.98 -27.6506 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L01 compound treatment 0.333 0.0169 1.36 0.333 0.0139 1.26 1.8545 0.9992 1035084 Maybridge3_000947 NS(=O)(=O)c1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L02 compound treatment 0.342 0.0259 2.09 0.351 0.0319 2.89 3.5223 0.9872 2075668 Maybridge3_000948 CCc1cccc(C(C)C)c1NC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L03 compound treatment 0.321 0.00494 0.4 0.332 0.0129 1.17 1.107 0.8973 2075669 Maybridge3_000949 COC(=S)Nc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L04 compound treatment 0.326 0.00994 0.8 0.333 0.0139 1.26 1.4559 0.9761 1575534 Maybridge3_000950 Nc1cc(nn1CCC#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L05 compound treatment 0.332 0.0159 1.28 0.33 0.0109 0.99 1.605 0.9915 2075670 Maybridge3_000951 N#CCc1nnc([nH]1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L06 compound treatment 0.332 0.0159 1.28 0.33 0.0109 0.99 1.605 0.9915 1316531 Maybridge3_000952 Oc1ccc(Br)cc1C(=O)NCCc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L07 compound treatment 0.331 0.0149 1.2 0.331 0.0119 1.08 1.6122 0.9985 2075671 Maybridge3_000953 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(CN3CCOCC3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L08 compound treatment 0.328 0.0119 0.96 0.33 0.0109 0.99 1.3772 0.9999 2075672 Maybridge3_000954 OCC1(CO)CS/C(=N\c2ccc(F)c(Cl)c2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L09 compound treatment 0.329 0.0129 1.04 0.334 0.0149 1.35 1.6909 0.9918 2075673 Maybridge3_000955 Clc1ccc(Cl)c(NC(=O)CC2SC(=NC2=O)NC3CC4CC3C=C4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L10 compound treatment 0.315 -0.00106 -0.09 0.329 0.00987 0.9 0.5728 0.6367 2075674 Maybridge3_000956 Cc1cc(nn1c2ccccc2)C(=O)n3nc(C)c(Br)c3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L11 compound treatment 0.353 0.0369 2.97 0.373 0.0539 4.89 5.5607 0.9716 2075675 Maybridge3_000957 NC1=C(C#N)C(C(=C(O1)c2cccs2)C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L12 compound treatment 0.334 0.0179 1.44 0.339 0.0199 1.8 2.2965 0.994 2075676 Maybridge3_000958 Clc1ccccc1NC2=C(C#N)C(=O)NC(S2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L13 compound treatment 0.334 0.0179 1.44 0.333 0.0139 1.26 1.9114 0.9976 2075677 Maybridge3_000959 Fc1cccc(Cl)c1CN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L14 compound treatment 0.326 0.00994 0.8 0.333 0.0139 1.26 1.4559 0.9761 2075678 Maybridge3_000960 Cc1nn(c(C)c1C#N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L15 compound treatment 0.329 0.0129 1.04 0.335 0.0159 1.44 1.7551 0.9874 2075679 Maybridge3_000961 NC(=O)c1snnc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L16 compound treatment 0.315 -0.00106 -0.09 0.326 0.00687 0.62 0.3802 0.6044 2075680 Maybridge3_000962 CSc1ccc(Oc2cc(F)ccc2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L17 compound treatment 0.33 0.0139 1.12 0.333 0.0139 1.26 1.6836 0.9984 2075681 Maybridge3_000963 COC(=O)c1ccccc1CS(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L18 compound treatment 0.328 0.0119 0.96 0.334 0.0149 1.35 1.6339 0.9862 2075682 Maybridge3_000964 Fc1ccccc1C(=O)Oc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L19 compound treatment 0.314 -0.00206 -0.17 0.317 -0.00213 -0.19 -0.2544 -0.9971 2075683 Maybridge3_000965 Fc1cccc(Cl)c1CSc2nnc(s2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L20 compound treatment 0.331 0.0149 1.2 0.326 0.00687 0.62 1.2913 0.9531 2075684 Maybridge3_000966 N#CCSc1nsc(SCC#N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L21 compound treatment 0.324 0.00794 0.64 0.343 0.0239 2.17 1.9839 0.8783 1042868 Maybridge3_000967 O=C(C1CCCCC1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L22 compound treatment 0.331 0.0149 1.2 0.328 0.00887 0.8 1.4197 0.9809 2075685 Maybridge3_000968 Cc1c(nnn1c2cccc(Cl)c2C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L23 mock treatment 0.322 0.00594 0.48 0.323 0.00387 0.35 0.5863 0.9884 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 L24 positive control 0.092 -0.224 -18.04 0.093 -0.226 -20.53 -27.2727 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M01 compound treatment 0.326 0.00994 0.8 0.326 0.00687 0.62 1.0066 0.9924 1247573 Maybridge3_000969 OC1(CCC2C1CCC2(O)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M02 compound treatment 0.321 0.00494 0.4 0.326 0.00687 0.62 0.7219 0.9764 2075686 Maybridge3_000970 O=C(CC1S/C(=N/c2ccccc2)/NC1=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M03 compound treatment 0.32 0.00394 0.32 0.33 0.0109 0.99 0.9217 0.8896 1300102 Maybridge3_000971 Clc1ccc(cc1)C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M04 compound treatment 0.325 0.00894 0.72 0.33 0.0109 0.99 1.2064 0.988 2075687 Maybridge3_000972 CC(C)c1ccc(/N=C/c2ccc(NC(=O)C)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M05 compound treatment 0.324 0.00794 0.64 0.323 0.00387 0.35 0.7002 0.9602 1560877 Maybridge3_000973 COc1ccccc1N2CCN(Cc3ccccc3F)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M06 compound treatment 0.452 0.136 10.95 0.456 0.137 12.42 16.5252 0.998 2075688 Maybridge3_000974 O=C/1Nc2ccccc2\C1=C/c3c[nH]c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M07 compound treatment 0.313 -0.00306 -0.25 0.321 0.00187 0.17 -0.0546 -0.1824 1054918 Maybridge3_000975 COc1ccc(cc1Br)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M08 compound treatment 0.336 0.0199 1.61 0.338 0.0189 1.71 2.3462 0.9995 2075689 Maybridge3_000976 COc1cc(ccc1O)C2NC(=O)C(=C(Nc3cccc(C)c3)S2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M09 compound treatment 0.322 0.00594 0.48 0.326 0.00687 0.62 0.7788 0.9914 2075690 Maybridge3_000977 CC1(C)C2CCC1(C)c3nc(N)nc(c23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M10 compound treatment 0.338 0.0219 1.77 0.348 0.0289 2.62 3.1019 0.9816 1622986 Maybridge3_000978 Nc1nc(nc2sc3CCCCCc3c12)c4ccncc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M11 compound treatment 0.317 9.37E-4 0.08 0.327 0.00787 0.71 0.5583 0.7775 2075691 Maybridge3_000979 COC(=O)C1(CCC(=O)C2(CCC1=O)C(=O)OC)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M12 compound treatment 0.323 0.00694 0.56 0.324 0.00487 0.44 0.7074 0.9932 2075692 Maybridge3_000980 O/N=C(\c1ccccc1)/c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M13 compound treatment 0.324 0.00794 0.64 0.319 -1.33E-4 -0.01 0.4434 0.6936 2075693 Maybridge3_000981 C/S(=N\S(=O)(=O)c1ccccc1)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M14 compound treatment 0.316 -6.25E-5 -0.01 0.329 0.00987 0.9 0.6297 0.7031 2075694 Maybridge3_000982 COc1cc(CSC2=NCCN2)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M15 compound treatment 0.32 0.00394 0.32 0.323 0.00387 0.35 0.4724 0.9987 1051739 Maybridge3_000983 OC(=O)CNC(=O)Cc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M16 compound treatment 0.382 0.0659 5.31 0.377 0.0579 5.25 7.4687 1.0 2075695 Maybridge3_000984 NC(=N)SCc1nc(no1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M17 compound treatment 0.318 0.00194 0.16 0.333 0.0139 1.26 1.0004 0.7887 1074888 Maybridge3_000985 O=C1CCCC(=O)C1CCC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M18 compound treatment 0.334 0.0179 1.44 0.337 0.0179 1.62 2.1681 0.9983 1426775 Maybridge3_000986 CC1CCN(Cc2nc(no2)c3ccc(Cl)cc3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M19 compound treatment 0.32 0.00394 0.32 0.322 0.00287 0.26 0.4082 0.9952 2075696 Maybridge3_000987 NC(=O)C1CC2CCC1CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M20 compound treatment 0.309 -0.00706 -0.57 0.31 -0.00913 -0.83 -0.9884 -0.9831 2075697 Maybridge3_000988 Nc1ccccc1SCc2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M21 compound treatment 0.324 0.00794 0.64 0.326 0.00687 0.62 0.8927 0.9999 1537706 Maybridge3_000989 COC(=O)C1(CC2CC3C1)CC(C2)(C3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M22 compound treatment 0.321 0.00494 0.4 0.327 0.00787 0.71 0.7861 0.9618 2075698 Maybridge3_000990 O=c1[nH]c(CN2CCCCC2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M23 mock treatment 0.314 -0.00206 -0.17 0.312 -0.00713 -0.65 -0.5753 -0.8606 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 M24 positive control 0.092 -0.224 -18.04 0.092 -0.227 -20.62 -27.3369 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N01 compound treatment 0.328 0.0119 0.96 0.334 0.0149 1.35 1.6339 0.9862 2075699 Maybridge3_000991 FC(F)(F)c1cccc(c1)S(=O)(=O)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N02 compound treatment 0.323 0.00694 0.56 0.32 8.67E-4 0.08 0.4507 0.7988 2075700 Maybridge3_000992 CCOC(=S)SCc1nc(no1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N03 compound treatment 0.323 0.00694 0.56 0.327 0.00787 0.71 0.8999 0.9926 1121997 Maybridge3_000993 COc1cccc(Oc2ccccc2C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N04 compound treatment 0.326 0.00994 0.8 0.333 0.0139 1.26 1.4559 0.9761 2075701 Maybridge3_000994 Cc1ccc(cc1)c2nc(O)cc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N05 compound treatment 0.328 0.0119 0.96 0.333 0.0139 1.26 1.5698 0.9911 2075702 Maybridge3_000995 FC(F)(F)c1cc(cc(c1)S(=O)(=O)Nc2cccnc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N06 compound treatment 0.328 0.0119 0.96 0.333 0.0139 1.26 1.5698 0.9911 2075703 Maybridge3_000996 Clc1cccc(c1C#N)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N07 compound treatment 0.323 0.00694 0.56 0.334 0.0149 1.35 1.3492 0.9238 2075704 Maybridge3_000997 OC(=O)c1nnn(c1c2ccccc2)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N08 compound treatment 0.33 0.0139 1.12 0.336 0.0169 1.53 1.8762 0.9883 2075705 Maybridge3_000998 CN(NS(=O)(=O)c1ccc(Cl)c(Cl)c1)c2cccc(F)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N09 compound treatment 0.326 0.00994 0.8 0.336 0.0169 1.53 1.6484 0.9542 2075706 Maybridge3_000999 OC(=O)c1ccc(CSc2ccc(Cl)cc2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N10 compound treatment 0.321 0.00494 0.4 0.329 0.00987 0.9 0.9144 0.9332 2075707 Maybridge3_001000 Cn1nccc1c2cc(Cl)cc(Cl)c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N11 compound treatment 0.326 0.00994 0.8 0.337 0.0179 1.62 1.7126 0.947 1102307 Maybridge3_001001 N#CC(CN1CCOCC1)CN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N12 compound treatment 0.328 0.0119 0.96 0.332 0.0129 1.17 1.5056 0.9953 1633599 Maybridge3_001002 Fc1ccc(NC(=O)CCCC(=O)Nc2ccc(F)cc2F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N13 compound treatment 0.335 0.0189 1.52 0.336 0.0169 1.53 2.1609 1.0 1719890 Maybridge3_001003 Fc1cccc(Cl)c1CN2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N14 compound treatment 0.329 0.0129 1.04 0.339 0.0199 1.8 2.0118 0.966 2075708 Maybridge3_001004 O/N=C/c1cc(Cl)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N15 compound treatment 0.324 0.00794 0.64 0.33 0.0109 0.99 1.1494 0.9779 2075709 Maybridge3_001005 N/C(=N\O)/c1snnc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N16 compound treatment 0.331 0.0149 1.2 0.333 0.0139 1.26 1.7406 0.9997 2075710 Maybridge3_001006 Clc1ccc(C(=O)N2CCSCC2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N17 compound treatment 0.331 0.0149 1.2 0.325 0.00587 0.53 1.2271 0.9328 1150414 Maybridge3_001007 OCCNc1cccc(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N18 compound treatment 0.329 0.0129 1.04 0.331 0.0119 1.08 1.4983 0.9999 2075711 Maybridge3_001008 CSCC(=N)NS(=O)(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N19 compound treatment 0.325 0.00894 0.72 0.33 0.0109 0.99 1.2064 0.988 2075712 Maybridge3_001009 CCOC(=O)C(C#N)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N20 compound treatment 0.314 -0.00206 -0.17 0.316 -0.00313 -0.28 -0.3186 -0.9672 1641517 Maybridge3_001010 Fc1cccc(NCCc2ccc(Cl)cc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N21 compound treatment 0.328 0.0119 0.96 0.329 0.00987 0.9 1.313 0.9994 2075713 Maybridge3_001011 CS/C(=N\c1ccccc1F)/Nc2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N22 compound treatment 0.316 -6.25E-5 -0.01 0.324 0.00487 0.44 0.3088 0.699 2075714 Maybridge3_001012 CCOC(=S)SCc1cc(F)cc2COCOc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N23 mock treatment 0.321 0.00494 0.4 0.319 -1.33E-4 -0.01 0.2726 0.6853 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 N24 positive control 0.092 -0.224 -18.04 0.091 -0.228 -20.71 -27.4011 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O01 compound treatment 0.339 0.0229 1.85 0.342 0.0229 2.08 2.7738 0.9983 2075715 Maybridge3_001013 N1C(Oc2ccccc12)C3Nc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O02 compound treatment 0.333 0.0169 1.36 0.338 0.0189 1.71 2.1754 0.9936 2073392 Maybridge3_001014 NC(=N)SCc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O03 compound treatment 0.335 0.0189 1.52 0.34 0.0209 1.89 2.4176 0.9942 1532488 Maybridge3_001015 O=S(=O)(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccc(C#N)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O04 compound treatment 0.349 0.0329 2.65 0.355 0.0359 3.26 4.1776 0.9948 2075716 Maybridge3_001016 Oc1ccc(Cl)cc1/C=N/c2ccc3cn[nH]c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O05 compound treatment 0.329 0.0129 1.04 0.327 0.00787 0.71 1.2416 0.983 1307355 Maybridge3_001017 COc1ccccc1N2CCN(Cc3ccc(C)cc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O06 compound treatment 0.334 0.0179 1.44 0.332 0.0129 1.17 1.8472 0.9944 2075717 Maybridge3_001018 CCOc1cc(OCC)c(/C=N/O)c(OCC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O07 compound treatment 0.323 0.00694 0.56 0.339 0.0199 1.8 1.6702 0.8847 2075718 Maybridge3_001019 COc1cc(SC)c(OC)cc1SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O08 compound treatment 0.35 0.0339 2.73 0.349 0.0299 2.71 3.8494 1.0 2075719 Maybridge3_001020 Cc1cccc(NC2=C(C#N)C(=O)NC3(CCCC3)S2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O09 compound treatment 0.337 0.0209 1.69 0.341 0.0219 1.98 2.5957 0.9967 1399951 Maybridge3_001021 CC(=O)OCc1ccccc1S(=O)(=O)c2ccccc2COC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O10 compound treatment 0.335 0.0189 1.52 0.344 0.0249 2.26 2.6744 0.9818 2075720 Maybridge3_001022 COc1ccc(CC/C(=C\2/C(=O)Nc3ccccc23)/C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O11 compound treatment 0.331 0.0149 1.2 0.336 0.0169 1.53 1.9331 0.9929 2075721 Maybridge3_001023 CC1(CCCC2(CCC1)C(=O)O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O12 compound treatment 0.327 0.0109 0.88 0.337 0.0179 1.62 1.7696 0.9588 2075722 Maybridge3_001024 NC(=N)SCc1cccc(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O13 compound treatment 0.332 0.0159 1.28 0.336 0.0169 1.53 1.9901 0.9962 1428708 Maybridge3_001025 OC(=O)Cc1ccccc1Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O14 compound treatment 0.321 0.00494 0.4 0.332 0.0129 1.17 1.107 0.8973 2075723 Maybridge3_001026 COc1ccc(cc1CSc2ccccn2)/C(=N/O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O15 compound treatment 0.334 0.0179 1.44 0.337 0.0179 1.62 2.1681 0.9983 1018022 Maybridge3_001027 OCC1C(CO)C2c3ccccc3C1c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O16 compound treatment 0.345 0.0289 2.33 0.351 0.0319 2.89 3.6931 0.9943 2075724 Maybridge3_001028 Clc1ccc(cc1)c2noc(CSC3=NCCN3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O17 compound treatment 0.332 0.0159 1.28 0.339 0.0199 1.8 2.1826 0.9861 2075725 Maybridge3_001029 CCC(C)(C)/C(=N/O)/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O18 compound treatment 0.149 -0.167 -13.45 0.151 -0.168 -15.26 -20.3043 -0.998 1056307 Maybridge3_001030 Clc1ccccc1C2C(C#N)(C#N)C2(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O19 compound treatment 0.327 0.0109 0.88 0.332 0.0129 1.17 1.4486 0.9903 2075726 Maybridge3_001031 CC(C)(O)C1(CCC2(C)CC1)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O20 compound treatment 0.329 0.0129 1.04 0.333 0.0139 1.26 1.6267 0.9956 2075727 Maybridge3_001032 FC(F)(F)c1cc(NC(=O)CC#N)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O21 compound treatment 0.31 -0.00606 -0.49 0.318 -0.00113 -0.1 -0.4179 -0.8377 1451360 Maybridge3_001033 OC(C1CCNCC1)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O22 compound treatment 0.336 0.0199 1.61 0.339 0.0199 1.8 2.4104 0.9983 1682023 Maybridge3_001034 Nc1ccccc1SCc2nc3ccccc3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O23 mock treatment 0.327 0.0109 0.88 0.325 0.00587 0.53 0.9993 0.971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 O24 positive control 0.092 -0.224 -18.04 0.091 -0.228 -20.71 -27.4011 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P01 compound treatment 0.33 0.0139 1.12 0.336 0.0169 1.53 1.8762 0.9883 2075728 Maybridge3_001035 Cc1onc(c1C(=O)n2cccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P02 compound treatment 0.33 0.0139 1.12 0.336 0.0169 1.53 1.8762 0.9883 2075729 Maybridge3_001036 NC(=O)CC(=O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P03 compound treatment 0.334 0.0179 1.44 0.347 0.0279 2.53 2.81 0.9647 1362369 Maybridge3_001037 CSC1=C(C#N)C(=O)NC2(CCCCC2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P04 compound treatment 0.324 0.00794 0.64 0.331 0.0119 1.08 1.2136 0.9689 1317178 Maybridge3_001038 O=c1cc(oc(=O)[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P05 compound treatment 0.331 0.0149 1.2 0.325 0.00587 0.53 1.2271 0.9328 2075730 Maybridge3_001039 NC(=O)CCNc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P06 compound treatment 0.327 0.0109 0.88 0.326 0.00687 0.62 1.0635 0.9857 2075731 Maybridge3_001040 CSc1cccc(NC(=O)c2ccccc2F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P07 compound treatment 0.332 0.0159 1.28 0.343 0.0239 2.17 2.4394 0.9688 2075732 Maybridge3_001041 CC1CCN(Cc2nc(no2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P08 compound treatment 0.327 0.0109 0.88 0.33 0.0109 0.99 1.3203 0.9984 2075733 Maybridge3_001042 OCC1(CO)CS/C(=N\c2cc(Cl)cc(Cl)c2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P09 compound treatment 0.327 0.0109 0.88 0.329 0.00987 0.9 1.2561 1.0 1723199 Maybridge3_001043 CN(C)c1c(F)cc(cc1F)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P10 compound treatment 0.321 0.00494 0.4 0.32 8.67E-4 0.08 0.3368 0.8309 2075734 Maybridge3_001044 CC(C)(C)Sc1ccccc1/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P11 compound treatment 0.342 0.0259 2.09 0.339 0.0199 1.8 2.752 0.9973 1707999 Maybridge3_001045 Nc1n[nH]c(Nc2cccc(Cl)c2Cl)c1C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P12 compound treatment 0.325 0.00894 0.72 0.324 0.00487 0.44 0.8213 0.9725 2075735 Maybridge3_001046 O=C(CCCC(=O)Nc1cccnc1)Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P13 compound treatment 0.331 0.0149 1.2 0.329 0.00987 0.9 1.4838 0.9895 2075736 Maybridge3_001047 O/N=C(/C(=O)c1ccco1)\c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P14 compound treatment 0.345 0.0289 2.33 0.339 0.0199 1.8 2.9229 0.992 2075737 Maybridge3_001048 Fc1ccc(NC(=O)/C=C/C(=O)Nc2ccc(F)c(Cl)c2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P15 compound treatment 0.327 0.0109 0.88 0.333 0.0139 1.26 1.5128 0.9848 2075738 Maybridge3_001049 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCCN2CCOCC2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P16 compound treatment 0.327 0.0109 0.88 0.328 0.00887 0.8 1.1919 0.999 2075739 Maybridge3_001050 Fc1cccc(F)c1C(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P17 compound treatment 0.321 0.00494 0.4 0.324 0.00487 0.44 0.5935 0.9986 2075740 Maybridge3_001051 Clc1c(Br)ccc(N2CCCC2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P18 compound treatment 0.318 0.00194 0.16 0.332 0.0129 1.17 0.9362 0.7945 2075741 Maybridge3_001052 CN(NC(=N)C)c1cccc(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P19 compound treatment 0.324 0.00794 0.64 0.33 0.0109 0.99 1.1494 0.9779 2075742 Maybridge3_001053 Clc1cccc(NCc2cccs2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P20 compound treatment 0.327 0.0109 0.88 0.329 0.00987 0.9 1.2561 1.0 2075743 Maybridge3_001054 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P21 compound treatment 0.328 0.0119 0.96 0.333 0.0139 1.26 1.5698 0.9911 2075744 Maybridge3_001055 O=C(N(CC#N)CC#N)c1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P22 compound treatment 0.326 0.00994 0.8 0.327 0.00787 0.71 1.0708 0.9984 1643711 Maybridge3_001056 Nc1nnc(SCc2cc(F)cc3COCOc23)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P23 mock treatment 0.319 0.00294 0.24 0.318 -0.00113 -0.1 0.0945 0.3664 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1433 P24 positive control 0.094 -0.222 -17.88 0.093 -0.226 -20.53 -27.1588 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A01 compound treatment 0.306 -0.00312 -0.25 0.309 8.12E-4 0.07 -0.1258 -0.4797 2075745 Maybridge3_001057 Cn1c(SCc2cc(F)cc3COCOc23)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A02 compound treatment 0.302 -0.00712 -0.57 0.307 -0.00119 -0.11 -0.4819 -0.8255 2075746 Maybridge3_001058 CC1=C(OC(=O)c2cccs2)C(=O)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A03 compound treatment 0.302 -0.00712 -0.57 0.31 0.00181 0.16 -0.2894 -0.4848 1367326 Maybridge3_001059 Cc1onc(c1C(O)c2ccc(F)cc2)c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A04 compound treatment 0.299 -0.0101 -0.82 0.306 -0.00219 -0.2 -0.7169 -0.8543 2075747 Maybridge3_001060 CC1SCC(CS1)NS(=O)(=O)c2cc(Cl)sc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A05 compound treatment 0.323 0.0139 1.12 0.327 0.0188 1.71 1.9975 0.9789 1220212 Maybridge3_001061 Cc1nn(CCC#N)c(C)c1Cc2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A06 compound treatment 0.3 -0.00912 -0.73 0.3 -0.00819 -0.74 -1.0451 -1.0 2075748 Maybridge3_001062 OC(=O)c1cccc(C(=O)O)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A07 compound treatment 0.315 0.00588 0.47 0.314 0.00581 0.53 0.7076 0.9985 1708285 Maybridge3_001063 Fc1c(CSC(=S)N2CCOCC2)cccc1CSC(=S)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A08 compound treatment 0.299 -0.0101 -0.82 0.296 -0.0122 -1.11 -1.3588 -0.9887 1248512 Maybridge3_001064 Cc1noc(C)c1S(=O)(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A09 compound treatment 0.297 -0.0121 -0.98 0.297 -0.0112 -1.02 -1.4085 -0.9998 2075749 Maybridge3_001065 Brc1ccc2oc(cc2c1)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A10 compound treatment 0.344 0.0349 2.81 0.344 0.0358 3.25 4.2844 0.9973 2075750 Maybridge3_001066 CS/C(=N\C#N)/NCc1c(N)cccc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A11 compound treatment 0.282 -0.0271 -2.18 0.282 -0.0262 -2.38 -3.2254 -0.9991 2075751 Maybridge3_001067 CSC(=NS(=O)(=O)c1cc(Cl)sc1Cl)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A12 compound treatment 0.314 0.00488 0.39 0.305 -0.00319 -0.29 0.073 0.1497 1418653 Maybridge3_001068 Nc1ccc(Oc2c(C#N)cccc2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A13 compound treatment 0.304 -0.00512 -0.41 0.303 -0.00519 -0.47 -0.6248 -0.9978 2075752 Maybridge3_001069 O=S(=O)(CS(=O)(=O)NCc1cccs1)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A14 compound treatment 0.298 -0.0111 -0.9 0.306 -0.00219 -0.2 -0.7739 -0.8434 2075753 Maybridge3_001070 CC(C)(C)C(=O)C(C#N)C(=O)Nc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A15 compound treatment 0.302 -0.00712 -0.57 0.306 -0.00219 -0.2 -0.5461 -0.8995 2075754 Maybridge3_001071 CC(C)NC(=O)n1ccc(n1)c2sc(C)nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A16 compound treatment 0.317 0.00788 0.63 0.323 0.0148 1.34 1.3992 0.9412 1739347 Maybridge3_001072 Clc1ccc(cc1)S(=O)(=O)Nc2n[nH]c3cccc(Cl)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A17 compound treatment 0.297 -0.0121 -0.98 0.302 -0.00619 -0.56 -1.0876 -0.9655 2075755 Maybridge3_001073 COc1ccc(cc1)c2c[nH]nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A18 compound treatment 0.3 -0.00912 -0.73 0.304 -0.00419 -0.38 -0.7884 -0.9529 1497137 Maybridge3_001074 Cc1cc(NC(=O)CSCC(=O)O)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A19 compound treatment 0.3 -0.00912 -0.73 0.304 -0.00419 -0.38 -0.7884 -0.9529 2075756 Maybridge3_001075 CN(C1CC2CC1C=C2)C(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A20 compound treatment 0.3 -0.00912 -0.73 0.304 -0.00419 -0.38 -0.7884 -0.9529 2075757 Maybridge3_001076 Oc1nccn(c2c(F)cccc2F)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A21 compound treatment 0.303 -0.00612 -0.49 0.305 -0.00319 -0.29 -0.5534 -0.9677 2075758 Maybridge3_001077 CS/C(=N\S(=O)(=O)c1ccccc1)/Nc2c(C)nn(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A22 compound treatment 0.3 -0.00912 -0.73 0.304 -0.00419 -0.38 -0.7884 -0.9529 1497628 Maybridge3_001078 CC(C)(C)c1ccc(cc1)c2cc(=O)[nH]c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A23 mock treatment 0.297 -0.0121 -0.98 0.297 -0.0112 -1.02 -1.4085 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 A24 positive control 0.082 -0.227 -18.29 0.08 -0.228 -20.71 -27.5789 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B01 compound treatment 0.33 0.0209 1.68 0.333 0.0248 2.25 2.7812 0.9896 1552202 Maybridge3_001079 Cc1nccnc1c2ccnn2S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B02 compound treatment 0.344 0.0349 2.81 0.346 0.0378 3.43 4.4128 0.995 1394454 Maybridge3_001080 CC1C(OCCN1C(=O)c2c(C)onc2c3ccccc3Cl)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B03 compound treatment 0.328 0.0189 1.52 0.324 0.0158 1.44 2.0897 0.9996 1168145 Maybridge3_001081 Clc1ccc(cc1)c2cncn2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B04 compound treatment 0.328 0.0189 1.52 0.33 0.0218 1.98 2.4748 0.9915 2075759 Maybridge3_001082 OC(=O)c1ccc(/N=C/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B05 compound treatment 0.326 0.0169 1.36 0.32 0.0118 1.07 1.7191 0.9931 1227005 Maybridge3_001083 CCn1cc(C(=O)O)c(=O)c2cc(Cl)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B06 compound treatment 0.331 0.0219 1.76 0.334 0.0258 2.34 2.9024 0.9901 1679835 Maybridge3_001084 N#CCc1ccc(NC2(C#N)C3CC4CC(C3)CC2C4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B07 compound treatment 0.321 0.0119 0.96 0.328 0.0198 1.8 1.9478 0.9563 1173406 Maybridge3_001085 CCNc1sc(C(=O)OC)c(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B08 compound treatment 0.34 0.0309 2.49 0.334 0.0258 2.34 3.4148 0.9996 1222507 Maybridge3_001086 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B09 compound treatment 0.329 0.0199 1.6 0.329 0.0208 1.89 2.4676 0.9966 1481233 Maybridge3_001087 Cc1nnc(NC(=O)c2ccccc2NC(=O)c3ccccc3)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B10 compound treatment 0.317 0.00788 0.63 0.319 0.0108 0.98 1.1424 0.9777 2075760 Maybridge3_001088 Cn1nc(cc1OC(=O)c2ccccc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B11 compound treatment 0.328 0.0189 1.52 0.365 0.0568 5.16 4.7213 0.8782 2075761 Maybridge3_001089 COc1ccc(/C=C/2\CN(C)C/C(=C\c3ccc(OC)cc3)/C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B12 compound treatment 0.318 0.00888 0.71 0.321 0.0128 1.16 1.3277 0.9727 2075762 Maybridge3_001090 COc1cc(nc(N)n1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B13 compound treatment 0.321 0.0119 0.96 0.315 0.00681 0.62 1.1134 0.9777 2075763 Maybridge3_001091 CC1CNC(=N1)SCc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B14 compound treatment 0.371 0.0619 4.98 0.373 0.0648 5.88 7.6832 0.9966 1118789 Maybridge3_001092 COc1nc-2c(Cc3ccccc32)c(c4ccc[nH]4)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B15 compound treatment 0.322 0.0129 1.04 0.321 0.0128 1.16 1.5555 0.9984 2075764 Maybridge3_001093 CCc1nc(no1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B16 compound treatment 0.262 -0.0471 -3.79 0.263 -0.0452 -4.1 -5.5837 -0.9992 2075765 Maybridge3_001094 COC(=O)C1=C(N)Oc2ccccc2C1C(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B17 compound treatment 0.327 0.0179 1.44 0.321 0.0128 1.16 1.8402 0.9944 2075766 Maybridge3_001095 CCOC(=O)/C(=C(\C)/c1ccc(NC(=O)C)cc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B18 compound treatment 0.333 0.0239 1.92 0.34 0.0318 2.89 3.4014 0.9805 1619856 Maybridge3_001096 Cc1sc(N)c(C(=O)c2cccs2)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B19 compound treatment 0.322 0.0129 1.04 0.323 0.0148 1.34 1.6839 0.9918 2075767 Maybridge3_001097 Cc1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B20 compound treatment 0.321 0.0119 0.96 0.33 0.0218 1.98 2.0762 0.9443 2075768 Maybridge3_001098 COC(=O)c1sccc1NC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B21 compound treatment 0.324 0.0149 1.2 0.327 0.0188 1.71 2.0545 0.985 2075769 Maybridge3_001099 CC1CNC(=N1)c2ccccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B22 compound treatment 0.321 0.0119 0.96 0.322 0.0138 1.25 1.5627 0.9911 1345582 Maybridge3_001100 CC1CN(CC(C)O1)c2ncnc3ccsc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B23 mock treatment 0.315 0.00588 0.47 0.311 0.00281 0.26 0.515 0.9581 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 B24 positive control 0.081 -0.228 -18.37 0.081 -0.227 -20.62 -27.5717 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C01 compound treatment 0.319 0.00988 0.8 0.325 0.0168 1.53 1.6414 0.9538 2075770 Maybridge3_001101 CCOC(=S)SCc1cc(Br)cc(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C02 compound treatment 0.238 -0.0711 -5.73 0.244 -0.0642 -5.83 -8.1698 -1.0 2075771 Maybridge3_001102 CC1=C(Sc2ccccc2)C(=NCCN1)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C03 compound treatment 0.316 0.00688 0.55 0.311 0.00281 0.26 0.572 0.9382 1441511 Maybridge3_001103 Cc1onc(c1C(=O)c2ccccc2O)c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C04 compound treatment 0.325 0.0159 1.28 0.323 0.0148 1.34 1.8547 0.9997 2075772 Maybridge3_001104 Cc1cc(C)n(n1)C2=NCCN2S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C05 compound treatment 0.318 0.00888 0.71 0.314 0.00581 0.53 0.8784 0.9889 2075773 Maybridge3_001105 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2ccc(cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C06 compound treatment 0.313 0.00388 0.31 0.319 0.0108 0.98 0.9146 0.8881 1630915 Maybridge3_001106 Clc1cccc(NC2CCSC2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C07 compound treatment 0.314 0.00488 0.39 0.319 0.0108 0.98 0.9716 0.9191 2075774 Maybridge3_001107 OC(=C(C#N)C#N)c1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C08 compound treatment 0.319 0.00988 0.8 0.323 0.0148 1.34 1.513 0.9686 2075775 Maybridge3_001108 CSc1cc(n[nH]1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C09 compound treatment 0.318 0.00888 0.71 0.318 0.00981 0.89 1.1352 0.994 2075776 Maybridge3_001109 O=C(Nc1ccccc1)C(C#N)C(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C10 compound treatment 0.323 0.0139 1.12 0.323 0.0148 1.34 1.7408 0.9958 1406131 Maybridge3_001110 NC(=O)C1CCN(CC1)S(=O)(=O)c2cc(Cl)sc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C11 compound treatment 0.309 -1.25E-4 -0.01 0.307 -0.00119 -0.11 -0.0833 -0.7698 2075777 Maybridge3_001111 Clc1cc(c(Cl)s1)S(=O)(=O)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C12 compound treatment 0.323 0.0139 1.12 0.321 0.0128 1.16 1.6124 0.9998 2075778 Maybridge3_001112 CC(C)(C)C(=O)NCCC1CC1(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C13 compound treatment 0.337 0.0279 2.24 0.334 0.0258 2.34 3.244 0.9998 1121384 Maybridge3_001113 Cn1ncc(c1N)c2nc(cs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C14 compound treatment 0.326 0.0169 1.36 0.323 0.0148 1.34 1.9116 1.0 2075779 Maybridge3_001114 COc1ccc(OCC(F)(F)F)c(c1)C(=O)Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C15 compound treatment 0.312 0.00288 0.23 0.311 0.00281 0.26 0.3442 0.9988 2075780 Maybridge3_001115 CCc1c[nH]nc1c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C16 compound treatment 0.314 0.00488 0.39 0.307 -0.00119 -0.11 0.2014 0.4946 1117781 Maybridge3_001116 Clc1cccc(Oc2ccc(cc2)c3ccn[nH]3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C17 compound treatment 0.324 0.0149 1.2 0.322 0.0138 1.25 1.7336 0.9997 2075781 Maybridge3_001117 Clc1ccc(NC(=O)CC2=NC(=O)CS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C18 compound treatment 0.325 0.0159 1.28 0.322 0.0138 1.25 1.7905 1.0 1547445 Maybridge3_001118 Clc1cc(CN2CCSCC2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C19 compound treatment 0.312 0.00288 0.23 0.306 -0.00219 -0.2 0.0233 0.0764 2075782 Maybridge3_001119 C(=C/c1cc[nH]n1)\C=C\c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C20 compound treatment 0.326 0.0169 1.36 0.334 0.0258 2.34 2.6177 0.9664 1278984 Maybridge3_001120 COc1ccc(Oc2cccc(Cl)c2CNC(=O)c3ccccc3N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C21 compound treatment 0.313 0.00388 0.31 0.314 0.00581 0.53 0.5937 0.9686 2075783 Maybridge3_001121 Oc1ccccc1C(=C)n2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C22 compound treatment 0.32 0.0109 0.88 0.322 0.0138 1.25 1.5058 0.9846 1103933 Maybridge3_001122 COC(=O)c1cc(O)n(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C23 mock treatment 0.303 -0.00612 -0.49 0.305 -0.00319 -0.29 -0.5534 -0.9677 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 C24 positive control 0.084 -0.225 -18.13 0.081 -0.227 -20.62 -27.4009 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D01 compound treatment 0.359 0.0499 4.02 0.357 0.0488 4.43 5.973 0.9988 1671574 Maybridge3_001123 C1CN(CCO1)c2cc(n[nH]2)c3ccc(Oc4ccccc4)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D02 compound treatment 0.328 0.0189 1.52 0.33 0.0218 1.98 2.4748 0.9915 2075784 Maybridge3_001124 CC(NC(=O)C(C)(C)C)c1ccc(C)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D03 compound treatment 0.324 0.0149 1.2 0.326 0.0178 1.62 1.9903 0.9891 1248603 Maybridge3_001125 O=C(Nc1ccc(cc1)c2cnco2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D04 compound treatment 0.326 0.0169 1.36 0.324 0.0158 1.44 1.9758 0.9996 2075785 Maybridge3_001126 CN(CCC#N)c1ccc(/C=N/c2ccc(cc2)C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D05 compound treatment 0.321 0.0119 0.96 0.327 0.0188 1.71 1.8837 0.9624 1586772 Maybridge3_001127 CC1N(CCc2sccc12)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D06 compound treatment 0.319 0.00988 0.8 0.318 0.00981 0.89 1.1921 0.9984 1310916 Maybridge3_001128 CC1CC(C)(C)CC1(Nc2ccc(CC#N)cc2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D07 compound treatment 0.329 0.0199 1.6 0.329 0.0208 1.89 2.4676 0.9966 2075786 Maybridge3_001129 Cc1ccc(cc1)C(=O)CN2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D08 compound treatment 0.349 0.0399 3.21 0.336 0.0278 2.52 4.0557 0.9929 2075787 Maybridge3_001130 Fc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D09 compound treatment 0.326 0.0169 1.36 0.326 0.0178 1.62 2.1042 0.9963 2075788 Maybridge3_001131 Clc1ccc(cc1)c2nn3c(nnc3s2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D10 compound treatment 0.317 0.00788 0.63 0.322 0.0138 1.25 1.335 0.9501 2075789 Maybridge3_001132 Cn1nc(cc1OC(=O)c2cccs2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D11 compound treatment 0.327 0.0179 1.44 0.328 0.0198 1.8 2.2895 0.9939 1024629 Maybridge3_001133 CC(C)(C)c1nc2ccccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D12 compound treatment 0.381 0.0719 5.79 0.376 0.0678 6.16 8.4452 0.9995 2075790 Maybridge3_001134 O=C(C=C1SCCS1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D13 compound treatment 0.322 0.0129 1.04 0.322 0.0138 1.25 1.6197 0.9955 2075791 Maybridge3_001135 CC1CN=C(N1)SCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D14 compound treatment 0.325 0.0159 1.28 0.329 0.0208 1.89 2.2398 0.9819 2075792 Maybridge3_001136 NC(=O)/C(=C/1\CCc2ccccc12)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D15 compound treatment 0.314 0.00488 0.39 0.328 0.0198 1.8 1.5493 0.8416 1373168 Maybridge3_001137 OC(=O)CCCc1nc(no1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D16 compound treatment 0.266 -0.0431 -3.47 0.258 -0.0502 -4.56 -5.6769 -0.991 2075793 Maybridge3_001138 CCOC(=O)C1=C(N)Oc2ccccc2C1C(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D17 compound treatment 0.396 0.0869 7.0 0.404 0.0958 8.7 11.0965 0.9942 1662876 Maybridge3_001139 OC(=O)CC1SC(=NC1=O)Cc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D18 compound treatment 0.339 0.0299 2.41 0.336 0.0278 2.52 3.4863 0.9997 1167009 Maybridge3_001140 CCOC(=O)c1cc(CC)sc1NC(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D19 compound treatment 0.322 0.0129 1.04 0.322 0.0138 1.25 1.6197 0.9955 1135722 Maybridge3_001141 Nc1ccc(Cl)cc1C(=O)NCc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D20 compound treatment 0.328 0.0189 1.52 0.326 0.0178 1.62 2.2181 0.9995 2075794 Maybridge3_001142 CCc1cc2c(OC(=O)N(C)C)ncnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D21 compound treatment 0.296 -0.0131 -1.06 0.301 -0.00719 -0.65 -1.2087 -0.9731 1231291 Maybridge3_001143 Nc1ccc(c(Cl)c1)S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D22 compound treatment 0.324 0.0149 1.2 0.328 0.0198 1.8 2.1187 0.9805 1248952 Maybridge3_001144 Clc1cccc(Cl)c1CSc2nc3ccnn3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D23 mock treatment 0.31 8.75E-4 0.07 0.31 0.00181 0.16 0.1662 0.9284 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 D24 positive control 0.086 -0.223 -17.97 0.084 -0.224 -20.35 -27.0944 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E01 compound treatment 0.327 0.0179 1.44 0.328 0.0198 1.8 2.2895 0.9939 2075795 Maybridge3_001145 Cc1cc(C)n(n1)C2=NCCN2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E02 compound treatment 0.33 0.0209 1.68 0.329 0.0208 1.89 2.5245 0.9983 2075796 Maybridge3_001146 CC1=C(OC(=O)/C=C/c2ccccc2)C(=O)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E03 compound treatment 0.322 0.0129 1.04 0.316 0.00781 0.71 1.2346 0.9828 2075797 Maybridge3_001147 Fc1ccc(cc1)C(=O)C2CC2C(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E04 compound treatment 0.322 0.0129 1.04 0.319 0.0108 0.98 1.4271 0.9996 2075798 Maybridge3_001148 ClC1(Cl)CC1CSC2=NCCN2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E05 compound treatment 0.335 0.0259 2.08 0.328 0.0198 1.8 2.745 0.9973 1308755 Maybridge3_001149 Clc1cccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E06 compound treatment 0.337 0.0279 2.24 0.326 0.0178 1.62 2.7305 0.987 2075799 Maybridge3_001150 CSc1nnc(CCCO)n1c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E07 compound treatment 0.325 0.0159 1.28 0.322 0.0138 1.25 1.7905 1.0 1680663 Maybridge3_001151 CC1=C(O)C(=O)OC1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E08 compound treatment 0.321 0.0119 0.96 0.333 0.0248 2.25 2.2688 0.9272 2075800 Maybridge3_001152 CSc1cc(nn1S(=O)(=O)c2ccc(Cl)cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E09 compound treatment 0.308 -0.00112 -0.09 0.312 0.00381 0.35 0.1806 0.505 2075801 Maybridge3_001153 Cc1nn(cc1c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E10 compound treatment 0.325 0.0159 1.28 0.322 0.0138 1.25 1.7905 1.0 2075802 Maybridge3_001154 Cc1ccnn1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E11 compound treatment 0.328 0.0189 1.52 0.322 0.0138 1.25 1.9613 0.9954 1665318 Maybridge3_001155 Cc1cc(NS(=O)(=O)c2cc(Cl)sc2Cl)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E12 compound treatment 0.323 0.0139 1.12 0.318 0.00981 0.89 1.4199 0.9937 2075803 Maybridge3_001156 CS/C(=N\C#N)/NCCC1CC1(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E13 compound treatment 0.341 0.0319 2.57 0.317 0.00881 0.8 2.3806 0.8855 2075804 Maybridge3_001157 OCCCc1[nH]nc(c1Br)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E14 compound treatment 0.318 0.00888 0.71 0.315 0.00681 0.62 0.9426 0.9974 2075805 Maybridge3_001158 O=C1CC(CC(=O)C1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E15 compound treatment 0.327 0.0179 1.44 0.32 0.0118 1.07 1.776 0.9895 2075806 Maybridge3_001159 CCc1cnc(N/C=N/O)nc1c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E16 compound treatment 0.391 0.0819 6.59 0.392 0.0838 7.61 10.0415 0.9975 2075807 Maybridge3_001160 CC(C)(C)c1csc(=S)n1CCc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E17 compound treatment 0.314 0.00488 0.39 0.319 0.0108 0.98 0.9716 0.9191 2075808 Maybridge3_001161 Cc1c(cnn1c2ccccc2)c3ccnc(N)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E18 compound treatment 0.309 -1.25E-4 -0.01 0.324 0.0158 1.44 1.0078 0.7021 2075809 Maybridge3_001162 CC(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E19 compound treatment 0.306 -0.00312 -0.25 0.311 0.00281 0.26 0.0026 0.0072 2075810 Maybridge3_001163 Clc1cc(C(=O)CSc2ccccn2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E20 compound treatment 0.32 0.0109 0.88 0.323 0.0148 1.34 1.57 0.9784 2075811 Maybridge3_001164 COC(=O)c1ccccc1N/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E21 compound treatment 0.32 0.0109 0.88 0.325 0.0168 1.53 1.6983 0.9652 1413743 Maybridge3_001165 Cc1nn(C)c(C)c1NC(=O)c2ccccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E22 compound treatment 0.307 -0.00212 -0.17 0.304 -0.00419 -0.38 -0.3898 -0.9351 1540816 Maybridge3_001166 CS(=O)(=O)NCc1c(Cl)cccc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E23 mock treatment 0.305 -0.00412 -0.33 0.306 -0.00219 -0.2 -0.3753 -0.9697 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 E24 positive control 0.087 -0.222 -17.89 0.085 -0.223 -20.26 -26.9733 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F01 compound treatment 0.324 0.0149 1.2 0.324 0.0158 1.44 1.8619 0.996 2075812 Maybridge3_001167 Cc1nc(CSc2ccc(Cl)cc2)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F02 compound treatment 0.352 0.0429 3.45 0.336 0.0278 2.52 4.2265 0.9882 2075813 Maybridge3_001168 CC(NC(=O)/C=C/c1ccccc1)c2ccc(C)cc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F03 compound treatment 0.323 0.0139 1.12 0.324 0.0158 1.44 1.805 0.9923 1247128 Maybridge3_001169 COC(=O)c1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F04 compound treatment 0.326 0.0169 1.36 0.329 0.0208 1.89 2.2967 0.9869 1200571 Maybridge3_001170 COc1ccc(CCNC(C#N)c2ccco2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F05 compound treatment 0.332 0.0229 1.84 0.327 0.0188 1.71 2.51 0.9993 1379769 Maybridge3_001171 CC1N(CCc2sccc12)C(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F06 compound treatment 0.333 0.0239 1.92 0.333 0.0248 2.25 2.9521 0.9969 1504019 Maybridge3_001172 CN(C)c1ccc(c(Cl)c1)c2nc(=O)c3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F07 compound treatment 0.329 0.0199 1.6 0.333 0.0248 2.25 2.7243 0.986 1015425 Maybridge3_001173 Cc1ccccc1NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F08 compound treatment 0.331 0.0219 1.76 0.328 0.0198 1.8 2.5172 0.9999 1249585 Maybridge3_001174 CCOC(=O)C(=C1C2CC3CC(C2)CC1C3)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F09 compound treatment 0.324 0.0149 1.2 0.328 0.0198 1.8 2.1187 0.9805 1632392 Maybridge3_001175 O=C1OCCN=C(c2ccccc2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F10 compound treatment 0.347 0.0379 3.05 0.347 0.0388 3.52 4.6478 0.9974 2075814 Maybridge3_001176 CSc1nc(nc(N)c1c2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F11 compound treatment 0.309 -1.25E-4 -0.01 0.31 0.00181 0.16 0.1092 0.6626 1720841 Maybridge3_001177 Fc1ccccc1n2c(csc2=N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F12 compound treatment 0.314 0.00488 0.39 0.317 0.00881 0.8 0.8432 0.9463 2075815 Maybridge3_001178 COC(=O)c1ccccc1NC(=S)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F13 compound treatment 0.33 0.0209 1.68 0.326 0.0178 1.62 2.3319 0.9998 2075816 Maybridge3_001179 Clc1ccc(cc1)c2ncon2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F14 compound treatment 0.323 0.0139 1.12 0.352 0.0438 3.98 3.6022 0.872 1629322 Maybridge3_001180 COc1nc-2c(Cc3cc(NC(=O)C)ccc32)c(c4ccco4)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F15 compound treatment 0.324 0.0149 1.2 0.328 0.0198 1.8 2.1187 0.9805 1482140 Maybridge3_001181 Cc1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F16 compound treatment 0.31 8.75E-4 0.07 0.313 0.00481 0.44 0.3587 0.8107 1742113 Maybridge3_001182 Cc1ccc(cc1)C(=O)Nc2nccc(n2)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F17 compound treatment 0.327 0.0179 1.44 0.324 0.0158 1.44 2.0327 1.0 1674958 Maybridge3_001183 Clc1ccccc1CC2=NC(=O)C(CC(=O)Nc3ccccc3)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F18 compound treatment 0.306 -0.00312 -0.25 0.314 0.00581 0.53 0.1951 0.3338 2075817 Maybridge3_001184 COC(=O)c1sccc1NC(=O)CSCc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F19 compound treatment 0.328 0.0189 1.52 0.32 0.0118 1.07 1.8329 0.9854 2075818 Maybridge3_001185 CC(C)(O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F20 compound treatment 0.329 0.0199 1.6 0.332 0.0238 2.16 2.6601 0.9891 2075819 Maybridge3_001186 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F21 compound treatment 0.322 0.0129 1.04 0.326 0.0178 1.62 1.8764 0.9769 2075820 Maybridge3_001187 FC(F)(F)c1cccc(c1)c2nnc(o2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F22 compound treatment 0.369 0.0599 4.82 0.386 0.0778 7.06 8.4037 0.9827 2075821 Maybridge3_001188 Nc1ncc(c2nc3ccccc3s2)c(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F23 mock treatment 0.311 0.00188 0.15 0.308 -1.88E-4 -0.02 0.0947 0.6235 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 F24 positive control 0.087 -0.222 -17.89 0.085 -0.223 -20.26 -26.9733 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G01 compound treatment 0.326 0.0169 1.36 0.32 0.0118 1.07 1.7191 0.9931 2075822 Maybridge3_001189 CN(c1cccc(F)c1C#N)n2c(C)ccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G02 compound treatment 0.327 0.0179 1.44 0.326 0.0178 1.62 2.1611 0.9983 2075823 Maybridge3_001190 c1coc(c1)c2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G03 compound treatment 0.318 0.00888 0.71 0.317 0.00881 0.8 1.071 0.9984 2075824 Maybridge3_001191 CSCC(CSC)OC(=O)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G04 compound treatment 0.323 0.0139 1.12 0.322 0.0138 1.25 1.6766 0.9983 1621848 Maybridge3_001192 Clc1ccc(cc1)S(=O)(=O)NC2CCSC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G05 compound treatment 0.323 0.0139 1.12 0.323 0.0148 1.34 1.7408 0.9958 2075825 Maybridge3_001193 Cc1cc(Cl)cc2S/C(=C/c3cccnc3)/C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G06 compound treatment 0.301 -0.00812 -0.65 0.299 -0.00919 -0.83 -1.0523 -0.9928 1156701 Maybridge3_001194 Fc1c(cccc1C(=O)Oc2ccccc2)C(=O)Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G07 compound treatment 0.338 0.0289 2.33 0.341 0.0328 2.98 3.7502 0.9925 2075826 Maybridge3_001195 Cc1cc(no1)n2c(C)ccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G08 compound treatment 0.319 0.00988 0.8 0.322 0.0138 1.25 1.4488 0.9759 2075827 Maybridge3_001196 O/N=C/c1ccc(o1)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G09 compound treatment 0.317 0.00788 0.63 0.324 0.0158 1.44 1.4633 0.9326 2075828 Maybridge3_001197 O/N=C/NC1=C(C(=O)c2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G10 compound treatment 0.302 -0.00712 -0.57 0.302 -0.00619 -0.56 -0.8028 -0.9999 1238271 Maybridge3_001198 Cn1cccc1C2=C(C#N)C(C(=C(N)O2)C#N)c3c(Cl)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G11 compound treatment 0.319 0.00988 0.8 0.313 0.00481 0.44 0.8712 0.9602 1441863 Maybridge3_001199 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G12 compound treatment 0.309 -1.25E-4 -0.01 0.32 0.0118 1.07 0.7511 0.7004 2075829 Maybridge3_001200 ClC1(Cl)CC1CCNS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G13 compound treatment 0.323 0.0139 1.12 0.318 0.00981 0.89 1.4199 0.9937 2075830 Maybridge3_001201 CNC(=O)n1cc(C)c(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G14 compound treatment 0.317 0.00788 0.63 0.322 0.0138 1.25 1.335 0.9501 2075831 Maybridge3_001202 CS(=O)(=O)N(CCc1ccc(Cl)cc1)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G15 compound treatment 0.311 0.00188 0.15 0.315 0.00681 0.62 0.544 0.8547 2075832 Maybridge3_001203 Cc1cn(nc1c2cccs2)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G16 compound treatment 0.322 0.0129 1.04 0.313 0.00481 0.44 1.042 0.9262 2075833 Maybridge3_001204 Clc1ccc(cc1)c2cc(=O)[nH]c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G17 compound treatment 0.331 0.0219 1.76 0.363 0.0548 4.98 4.7637 0.9026 2075834 Maybridge3_001205 Cc1n[nH]cc1c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G18 compound treatment 0.325 0.0159 1.28 0.331 0.0228 2.07 2.3682 0.9731 2075835 Maybridge3_001206 Clc1ccc(cc1)C2CC(=O)C=C(C2)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G19 compound treatment 0.322 0.0129 1.04 0.323 0.0148 1.34 1.6839 0.9918 2075836 Maybridge3_001207 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(C)c(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G20 compound treatment 0.345 0.0359 2.89 0.345 0.0368 3.34 4.4056 0.9974 2075837 Maybridge3_001208 CN(NC1OC(=O)c2ccccc12)c3cc(cc(C)n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G21 compound treatment 0.319 0.00988 0.8 0.322 0.0138 1.25 1.4488 0.9759 2075838 Maybridge3_001209 O/N=C/NC1CCCCNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G22 compound treatment 0.325 0.0159 1.28 0.326 0.0178 1.62 2.0472 0.9932 2075839 Maybridge3_001210 CC(=O)NCc1c(Cl)cccc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G23 mock treatment 0.305 -0.00412 -0.33 0.308 -1.88E-4 -0.02 -0.2469 -0.7424 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 G24 positive control 0.089 -0.22 -17.73 0.086 -0.222 -20.17 -26.7952 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H01 compound treatment 0.336 0.0269 2.16 0.333 0.0248 2.25 3.1229 0.9998 2075840 Maybridge3_001211 CC(C)(C)n1ccc(n1)c2cc(F)cc(F)c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H02 compound treatment 0.327 0.0179 1.44 0.332 0.0238 2.16 2.5462 0.9805 1084493 Maybridge3_001212 Cc1c(C#N)c(N)sc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H03 compound treatment 0.329 0.0199 1.6 0.319 0.0108 0.98 1.8257 0.9724 2075841 Maybridge3_001213 COC(=O)c1cccc(NC(=O)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H04 compound treatment 0.334 0.0249 2.0 0.327 0.0188 1.71 2.6239 0.9968 1591706 Maybridge3_001214 COc1ccc(CCNC(C#N)c2cc(Br)ccc2O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H05 compound treatment 0.327 0.0179 1.44 0.326 0.0178 1.62 2.1611 0.9983 2075842 Maybridge3_001215 COC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H06 compound treatment 0.318 0.00888 0.71 0.316 0.00781 0.71 1.0068 1.0 1577664 Maybridge3_001216 Oc1ccc(Br)cc1CNc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H07 compound treatment 0.218 -0.0911 -7.34 0.224 -0.0842 -7.64 -10.5923 -0.9998 2075843 Maybridge3_001217 CCOC(=O)/C(=C\1/C(=O)Nc2ccc(Br)cc12)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H08 compound treatment 0.326 0.0169 1.36 0.321 0.0128 1.16 1.7832 0.997 1340707 Maybridge3_001218 Cc1noc(N2C(=O)C3C4CC(C=C4)C3C2=O)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H09 compound treatment 0.293 -0.0161 -1.3 0.288 -0.0202 -1.83 -2.2139 -0.9858 1002388 Maybridge3_001219 O=C(CSC#N)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H10 compound treatment 0.323 0.0139 1.12 0.326 0.0178 1.62 1.9334 0.9837 2075844 Maybridge3_001220 COC(=O)c1cc2c(C)nn(C)c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H11 compound treatment 0.286 -0.0231 -1.86 0.281 -0.0272 -2.47 -3.0618 -0.9904 1713070 Maybridge3_001221 CSc1cccc(c1)n2c(csc2=N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H12 compound treatment 0.34 0.0309 2.49 0.343 0.0348 3.16 3.9925 0.993 2075845 Maybridge3_001222 Clc1ccccc1SC(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H13 compound treatment 0.324 0.0149 1.2 0.336 0.0278 2.52 2.6321 0.942 2075846 Maybridge3_001223 Clc1ccc2OC(Nc2c1)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H14 compound treatment 0.343 0.0339 2.73 0.346 0.0378 3.43 4.3559 0.9935 1544404 Maybridge3_001224 Cc1ccc2N=C(CC(=O)Nc2c1C)c3ccccc3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H15 compound treatment 0.316 0.00688 0.55 0.317 0.00881 0.8 0.9571 0.9838 2075847 Maybridge3_001225 CSC1=NCCCN1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H16 compound treatment 0.352 0.0429 3.45 0.356 0.0478 4.34 5.5102 0.9936 2075848 Maybridge3_001226 N/C(=C(\N=C\c1ccc(Cl)cc1)/C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H17 compound treatment 0.334 0.0249 2.0 0.325 0.0168 1.53 2.4955 0.991 1151352 Maybridge3_001227 CN(C)c1ccc(cc1)C2Nc3ccc(C)cc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H18 compound treatment 0.299 -0.0101 -0.82 0.322 0.0138 1.25 0.31 0.2073 2075849 Maybridge3_001228 CCOC(=O)c1c(C)csc1NC(=O)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H19 compound treatment 0.32 0.0109 0.88 0.317 0.00881 0.8 1.1849 0.999 1393284 Maybridge3_001229 Clc1ccc(cc1)C(=C)NCc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H20 compound treatment 0.318 0.00888 0.71 0.322 0.0138 1.25 1.3919 0.9645 2075850 Maybridge3_001230 CSc1nc(=O)c2sccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H21 compound treatment 0.324 0.0149 1.2 0.328 0.0198 1.8 2.1187 0.9805 2075851 Maybridge3_001231 Cc1ccc(c2nnc(o2)c3ccncc3)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H22 compound treatment 0.326 0.0169 1.36 0.328 0.0198 1.8 2.2325 0.9904 2075852 Maybridge3_001232 NC(=O)c1sccc1NS(=O)(=O)c2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H23 mock treatment 0.308 -0.00112 -0.09 0.311 0.00281 0.26 0.1165 0.4299 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 H24 positive control 0.091 -0.218 -17.56 0.087 -0.221 -20.08 -26.6172 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I01 compound treatment 0.321 0.0119 0.96 0.324 0.0158 1.44 1.6911 0.9805 1091165 Maybridge3_001233 Cc1onc(c1C(=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I02 compound treatment 0.331 0.0219 1.76 0.33 0.0218 1.98 2.6456 0.9983 2075853 Maybridge3_001234 Cc1nn(C)c(Cl)c1S(=O)(=O)Nc2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I03 compound treatment 0.335 0.0259 2.08 0.334 0.0258 2.34 3.1301 0.9983 2075854 Maybridge3_001235 O/N=C(\NCCc1ccncc1)/C(c2ccccc2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I04 compound treatment 0.325 0.0159 1.28 0.322 0.0138 1.25 1.7905 1.0 2075855 Maybridge3_001236 Clc1cccc(c1)C(=O)NC2CCSC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I05 compound treatment 0.322 0.0129 1.04 0.32 0.0118 1.07 1.4913 0.9999 2075856 Maybridge3_001237 CC(C)(COC(=O)Nc1ccc(Cl)cc1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I06 compound treatment 0.332 0.0229 1.84 0.326 0.0178 1.62 2.4458 0.9979 1340148 Maybridge3_001238 Fc1c(cccc1C(=O)N2CCCCC2)C(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I07 compound treatment 0.326 0.0169 1.36 0.335 0.0268 2.43 2.6818 0.9621 1231777 Maybridge3_001239 Cc1cc(NC(=O)CC#N)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I08 compound treatment 0.319 0.00988 0.8 0.33 0.0218 1.98 1.9623 0.9197 2075857 Maybridge3_001240 Fc1ccc(cc1)C(=O)NCc2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I09 compound treatment 0.321 0.0119 0.96 0.315 0.00681 0.62 1.1134 0.9777 2075858 Maybridge3_001241 CSc1ccccc1NC(=O)c2cc(Cl)sc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I10 compound treatment 0.321 0.0119 0.96 0.324 0.0158 1.44 1.6911 0.9805 2075859 Maybridge3_001242 CS(=O)(=O)Nc1cc(NS(=O)(=O)C)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I11 compound treatment 0.315 0.00588 0.47 0.312 0.00381 0.35 0.5792 0.9882 1657518 Maybridge3_001243 O=C(Nc1ccccc1Oc2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I12 compound treatment 0.318 0.00888 0.71 0.316 0.00781 0.71 1.0068 1.0 1464788 Maybridge3_001244 CS(=O)(=O)Nc1ccc(Oc2c(C#N)cccc2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I13 compound treatment 0.314 0.00488 0.39 0.31 0.00181 0.16 0.3939 0.9255 1235084 Maybridge3_001245 CN(C)c1cccc(N(C)C)c1CNS(=O)(=O)c2cc(Cl)sc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I14 compound treatment 0.326 0.0169 1.36 0.325 0.0168 1.53 2.04 0.9983 2075860 Maybridge3_001246 NS(=O)(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I15 compound treatment 0.305 -0.00412 -0.33 0.33 0.0218 1.98 1.1652 0.5804 2075861 Maybridge3_001247 Cc1nc(C)c(s1)c2ccnc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I16 compound treatment 0.303 -0.00612 -0.49 0.306 -0.00219 -0.2 -0.4892 -0.92 1459848 Maybridge3_001248 CSc1nnc(SC2=CC(=O)CC(C2)c3ccccc3)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I17 compound treatment 0.34 0.0309 2.49 0.332 0.0238 2.16 3.2865 0.9976 1511153 Maybridge3_001249 Cc1nc(C)c(s1)c2cnc(NS(=O)(=O)c3ccc(Cl)cc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I18 compound treatment 0.321 0.0119 0.96 0.319 0.0108 0.98 1.3702 0.9999 2075862 Maybridge3_001250 CS/C(=N/C#N)/NCc1c(Cl)cccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I19 compound treatment 0.304 -0.00512 -0.41 0.309 8.12E-4 0.07 -0.2397 -0.5717 1613492 Maybridge3_001251 CN(C1CC2CC1C=C2)S(=O)(=O)c3cc(Cl)sc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I20 compound treatment 0.332 0.0229 1.84 0.33 0.0218 1.98 2.7026 0.9993 2075863 Maybridge3_001252 Cc1cc(cc(n1)n2cc(C#N)c(N)n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I21 compound treatment 0.327 0.0179 1.44 0.32 0.0118 1.07 1.776 0.9895 1646441 Maybridge3_001253 Clc1cccc(NC2CCCCNC2=O)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I22 compound treatment 0.319 0.00988 0.8 0.325 0.0168 1.53 1.6414 0.9538 1521899 Maybridge3_001254 CC(=O)N1CCC(CC1)NC(=O)Oc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I23 mock treatment 0.312 0.00288 0.23 0.31 0.00181 0.16 0.28 0.986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 I24 positive control 0.094 -0.215 -17.32 0.087 -0.221 -20.08 -26.4463 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J01 compound treatment 0.329 0.0199 1.6 0.328 0.0198 1.8 2.4034 0.9983 1637576 Maybridge3_001255 CC(C)N1CCS(=O)(=O)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J02 compound treatment 0.336 0.0269 2.16 0.329 0.0208 1.89 2.8661 0.9977 1297552 Maybridge3_001256 COc1cc(cc(OC)c1OC)C(=O)NC(C)(C)CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J03 compound treatment 0.308 -0.00112 -0.09 0.323 0.0148 1.34 0.8867 0.658 1728518 Maybridge3_001257 COC(=O)c1cccc(NC(=O)C(C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J04 compound treatment 0.326 0.0169 1.36 0.325 0.0168 1.53 2.04 0.9983 1722497 Maybridge3_001258 Brc1ccc(cc1)S(=O)(=O)N(CCC#N)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J05 compound treatment 0.327 0.0179 1.44 0.327 0.0188 1.71 2.2253 0.9964 1211575 Maybridge3_001259 COC(=O)c1cccc(NS(=O)(=O)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J06 compound treatment 0.328 0.0189 1.52 0.334 0.0258 2.34 2.7315 0.978 1680927 Maybridge3_001260 N#CCc1ccc(NC2(CCCC2)C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J07 compound treatment 0.331 0.0219 1.76 0.33 0.0218 1.98 2.6456 0.9983 1729902 Maybridge3_001261 Oc1nnc(c2ccc(Cl)cc2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J08 compound treatment 0.306 -0.00312 -0.25 0.318 0.00981 0.89 0.4519 0.4882 2075864 Maybridge3_001262 CS/C(=N\C(=O)c1c(Cl)cccc1Cl)/NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J09 compound treatment 0.317 0.00788 0.63 0.309 8.12E-4 0.07 0.5006 0.7841 1244183 Maybridge3_001263 Clc1ccc(c(Cl)c1)n2c(csc2=N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J10 compound treatment 0.387 0.0779 6.27 0.383 0.0748 6.79 9.2361 0.9992 2075865 Maybridge3_001264 CSC(=CC(=O)c1cccs1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J11 compound treatment 0.322 0.0129 1.04 0.322 0.0138 1.25 1.6197 0.9955 1718424 Maybridge3_001265 CN1C(=O)CN(C2CCCCC2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J12 compound treatment 0.513 0.204 16.42 0.52 0.212 19.23 25.204 0.9969 2075866 Maybridge3_001266 CNC(=O)Sc1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J13 compound treatment 0.315 0.00588 0.47 0.322 0.0138 1.25 1.2211 0.9112 2075867 Maybridge3_001267 Clc1ccc(cc1)C2Nc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J14 compound treatment 0.324 0.0149 1.2 0.332 0.0238 2.16 2.3754 0.9612 2075868 Maybridge3_001268 O=C1ON=C(C1C=C2CCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J15 compound treatment 0.318 0.00888 0.71 0.329 0.0208 1.89 1.8412 0.9116 1290526 Maybridge3_001269 Clc1ccccc1c2csc(n2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J16 compound treatment 0.358 0.0489 3.94 0.378 0.0698 6.34 7.2639 0.9738 2075869 Maybridge3_001270 N/C(=C(\N=C\c1ccc(cc1)C(F)(F)F)/C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J17 compound treatment 0.312 0.00288 0.23 0.314 0.00581 0.53 0.5368 0.9316 1175688 Maybridge3_001271 COc1ccc(cc1OC)C2Nc3cc(C)ccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J18 compound treatment 0.323 0.0139 1.12 0.321 0.0128 1.16 1.6124 0.9998 2075870 Maybridge3_001272 Cc1csc(NC(=O)C(F)(F)F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J19 compound treatment 0.323 0.0139 1.12 0.331 0.0228 2.07 2.2543 0.9581 1527880 Maybridge3_001273 Clc1ccccc1c2nc3ccccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J20 compound treatment 0.326 0.0169 1.36 0.327 0.0188 1.71 2.1684 0.9936 2075871 Maybridge3_001274 Cn1cc(Br)c(NS(=O)(=O)c2ccccc2C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J21 compound treatment 0.309 -1.25E-4 -0.01 0.314 0.00581 0.53 0.366 0.6935 2075872 Maybridge3_001275 Oc1ccccc1/C=N/c2ccc(c(Cl)c2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J22 compound treatment 0.331 0.0219 1.76 0.335 0.0268 2.43 2.9665 0.9874 2075873 Maybridge3_001276 COC(=O)/C(=C\1/CCSC1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J23 mock treatment 0.308 -0.00112 -0.09 0.308 -1.88E-4 -0.02 -0.0761 -0.8255 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 J24 positive control 0.09 -0.219 -17.65 0.088 -0.22 -19.99 -26.6099 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K01 compound treatment 0.348 0.0389 3.13 0.344 0.0358 3.25 4.5122 0.9998 2075874 Maybridge3_001277 Nc1nnc(SCc2c(nnn2c3ccc(F)cc3F)c4ccccc4)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K02 compound treatment 0.331 0.0219 1.76 0.326 0.0178 1.62 2.3889 0.9991 1228040 Maybridge3_001278 NC(=O)C1CCN(CC1)c2cccc(Cl)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K03 compound treatment 0.322 0.0129 1.04 0.321 0.0128 1.16 1.5555 0.9984 2075875 Maybridge3_001279 NC(=O)c1ccccc1Oc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K04 compound treatment 0.327 0.0179 1.44 0.327 0.0188 1.71 2.2253 0.9964 2075876 Maybridge3_001280 Cc1cnnn1c2c(C)nn(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K05 compound treatment 0.333 0.0239 1.92 0.332 0.0238 2.16 2.8879 0.9983 1420885 Maybridge3_001281 Fc1c(CN2CCOCC2)cccc1CN3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K06 compound treatment 0.316 0.00688 0.55 0.32 0.0118 1.07 1.1497 0.9527 2075877 Maybridge3_001282 Cc1c(nnn1c2cc(Cl)ccc2Cl)c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K07 compound treatment 0.313 0.00388 0.31 0.327 0.0188 1.71 1.4281 0.8227 2075878 Maybridge3_001283 c1cc(n[nH]1)c2cc3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K08 compound treatment 0.307 -0.00212 -0.17 0.315 0.00681 0.62 0.3163 0.4929 2075879 Maybridge3_001284 Fc1ccc(c2ccc(CNC(=O)c3ccccc3)o2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K09 compound treatment 0.318 0.00888 0.71 0.321 0.0128 1.16 1.3277 0.9727 2075880 Maybridge3_001285 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K10 compound treatment 0.304 -0.00512 -0.41 0.311 0.00281 0.26 -0.1113 -0.2294 1174817 Maybridge3_001286 Cn1cccc1C2=C(C#N)C(C(=C(N)O2)C#N)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K11 compound treatment 0.322 0.0129 1.04 0.319 0.0108 0.98 1.4271 0.9996 1525251 Maybridge3_001287 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K12 compound treatment 0.318 0.00888 0.71 0.324 0.0158 1.44 1.5203 0.9482 2075881 Maybridge3_001288 CSc1cc(nn1C(=O)Nc2ccccc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K13 compound treatment 0.322 0.0129 1.04 0.321 0.0128 1.16 1.5555 0.9984 1434021 Maybridge3_001289 CSc1nc(NS(=O)(=O)c2ccc(F)cc2F)nn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K14 compound treatment 0.311 0.00188 0.15 0.322 0.0138 1.25 0.9933 0.7866 2075882 Maybridge3_001290 Fc1ccc(NC(=O)CSc2ccccn2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K15 compound treatment 0.323 0.0139 1.12 0.319 0.0108 0.98 1.4841 0.9979 2075883 Maybridge3_001291 Cc1nc(C)c(s1)c2ccnc(N/C=N/O)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K16 compound treatment 0.328 0.0189 1.52 0.329 0.0208 1.89 2.4106 0.9942 2075884 Maybridge3_001292 NC(=O)CC(=O)c1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K17 compound treatment 0.31 8.75E-4 0.07 0.314 0.00581 0.53 0.4229 0.7945 2075885 Maybridge3_001293 Cc1c(cnn1c2ccccc2)c3ccnn3C(=O)Nc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K18 compound treatment 0.32 0.0109 0.88 0.316 0.00781 0.71 1.1207 0.9945 1638955 Maybridge3_001294 Nc1n[nH]c(NCc2c(Cl)cccc2Oc3ccccc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K19 compound treatment 0.321 0.0119 0.96 0.317 0.00881 0.8 1.2418 0.9961 1124837 Maybridge3_001295 CCc1c(CC)c(sc1C#N)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K20 compound treatment 0.303 -0.00612 -0.49 0.311 0.00281 0.26 -0.1682 -0.3029 1471850 Maybridge3_001296 O(c1ccccc1)c2ccc(cc2)c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K21 compound treatment 0.325 0.0159 1.28 0.326 0.0178 1.62 2.0472 0.9932 1730052 Maybridge3_001297 Cc1nn(C)c(C)c1NC(=O)c2ccccc2NC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K22 compound treatment 0.323 0.0139 1.12 0.331 0.0228 2.07 2.2543 0.9581 1391203 Maybridge3_001298 CSC(=CC(=O)c1ccc(Oc2ccccc2)cc1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K23 mock treatment 0.306 -0.00312 -0.25 0.308 -1.88E-4 -0.02 -0.19 -0.7532 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 K24 positive control 0.092 -0.217 -17.48 0.088 -0.22 -19.99 -26.496 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L01 compound treatment 0.336 0.0269 2.16 0.331 0.0228 2.07 2.9945 0.9998 2075886 Maybridge3_001299 Nc1ccc(cc1)c2cnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L02 compound treatment 0.337 0.0279 2.24 0.335 0.0268 2.43 3.3082 0.9992 2075887 Maybridge3_001300 CNC(=O)c1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L03 compound treatment 0.33 0.0209 1.68 0.333 0.0248 2.25 2.7812 0.9896 1331061 Maybridge3_001301 COC(=O)c1cccc(NC(=O)C2CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L04 compound treatment 0.326 0.0169 1.36 0.322 0.0138 1.25 1.8474 0.9992 2075888 Maybridge3_001302 NC1=Nc2ccc(Cl)cc2C1(O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L05 compound treatment 0.335 0.0259 2.08 0.328 0.0198 1.8 2.745 0.9973 2075889 Maybridge3_001303 CC1N(CCc2sccc12)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L06 compound treatment 0.342 0.0329 2.65 0.332 0.0238 2.16 3.4003 0.9949 2075890 Maybridge3_001304 COc1cc(NC(=O)/C=C/c2ccccc2Cl)c(OC)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L07 compound treatment 0.324 0.0149 1.2 0.331 0.0228 2.07 2.3112 0.9661 1446051 Maybridge3_001305 O=C(Nc1ccccc1C(=O)Nc2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L08 compound treatment 0.331 0.0219 1.76 0.325 0.0168 1.53 2.3247 0.9974 1539708 Maybridge3_001306 CC(=O)Nc1ccc(cc1)C(=O)CCC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L09 compound treatment 0.323 0.0139 1.12 0.324 0.0158 1.44 1.805 0.9923 2075891 Maybridge3_001307 Cc1c(C)c(C)c(CS/C(=N/N)/N)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L10 compound treatment 0.322 0.0129 1.04 0.327 0.0188 1.71 1.9406 0.9714 2075892 Maybridge3_001308 CCOc1cc(nc(N)n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L11 compound treatment 0.306 -0.00312 -0.25 0.316 0.00781 0.71 0.3235 0.4299 1265243 Maybridge3_001309 COc1ccc(cc1OC)n2c(csc2=N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L12 compound treatment 0.346 0.0369 2.97 0.342 0.0338 3.07 4.27 0.9999 2075893 Maybridge3_001310 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L13 compound treatment 0.325 0.0159 1.28 0.329 0.0208 1.89 2.2398 0.9819 2075894 Maybridge3_001311 COc1ccc(cc1)c2noc(CCC(=O)O)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L14 compound treatment 0.346 0.0369 2.97 0.357 0.0488 4.43 5.2327 0.9811 1413345 Maybridge3_001312 COc1ccc2OC(=C(C#N)C(C(C#N)C#N)c2c1)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L15 compound treatment 0.321 0.0119 0.96 0.324 0.0158 1.44 1.6911 0.9805 2075895 Maybridge3_001313 Cc1nc(cs1)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L16 compound treatment 0.32 0.0109 0.88 0.326 0.0178 1.62 1.7625 0.9585 1496287 Maybridge3_001314 Cc1cc(Cl)ccc1OCC2NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L17 compound treatment 0.33 0.0209 1.68 0.334 0.0258 2.34 2.8454 0.9867 1209869 Maybridge3_001315 CC(=O)Nc1ccc(cc1)C2Nc3ccc(C)cc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L18 compound treatment 0.329 0.0199 1.6 0.326 0.0178 1.62 2.275 1.0 2075896 Maybridge3_001316 Cc1csc(NC(=O)C(F)(F)F)c1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L19 compound treatment 0.322 0.0129 1.04 0.32 0.0118 1.07 1.4913 0.9999 1639375 Maybridge3_001317 Clc1cc(NC(=O)c2ccccc2)ccc1N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L20 compound treatment 0.328 0.0189 1.52 0.329 0.0208 1.89 2.4106 0.9942 2075897 Maybridge3_001318 CCOC(=O)CC(=O)Nc1ccn(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L21 compound treatment 0.327 0.0179 1.44 0.33 0.0218 1.98 2.4179 0.9877 2075898 Maybridge3_001319 Oc1ccc(Cl)cc1/C=N/Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L22 compound treatment 0.326 0.0169 1.36 0.329 0.0208 1.89 2.2967 0.9869 1577472 Maybridge3_001320 CCOC(=O)CC(=O)Nc1ccsc1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L23 mock treatment 0.312 0.00288 0.23 0.31 0.00181 0.16 0.28 0.986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 L24 positive control 0.093 -0.216 -17.4 0.089 -0.219 -19.9 -26.3749 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M01 compound treatment 0.328 0.0189 1.52 0.326 0.0178 1.62 2.2181 0.9995 1492038 Maybridge3_001321 CC(C)(C)C(=O)CSc1nc(N)c(s1)C(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M02 compound treatment 0.325 0.0159 1.28 0.323 0.0148 1.34 1.8547 0.9997 2075899 Maybridge3_001322 c1cc([nH]n1)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M03 compound treatment 0.323 0.0139 1.12 0.321 0.0128 1.16 1.6124 0.9998 1674378 Maybridge3_001323 Fc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M04 compound treatment 0.32 0.0109 0.88 0.315 0.00681 0.62 1.0565 0.9855 1467781 Maybridge3_001324 Clc1cccc(c1)C(=O)Nc2ccccc2C(=O)NC3CCSC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M05 compound treatment 0.33 0.0209 1.68 0.325 0.0168 1.53 2.2678 0.9988 2075900 Maybridge3_001325 CCOC(=O)c1sc2cccc(Cl)c2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M06 compound treatment 0.333 0.0239 1.92 0.329 0.0208 1.89 2.6953 1.0 2075901 Maybridge3_001326 CS/C(=N\S(=O)(=O)/C=C/c1ccccc1)/NN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M07 compound treatment 0.322 0.0129 1.04 0.33 0.0218 1.98 2.1332 0.9544 2075902 Maybridge3_001327 CSCC(=O)Nc1cc(C)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M08 compound treatment 0.324 0.0149 1.2 0.328 0.0198 1.8 2.1187 0.9805 1605779 Maybridge3_001328 Cc1onc(c1C(=O)NCc2cc(Cl)cc(Cl)c2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M09 compound treatment 0.324 0.0149 1.2 0.329 0.0208 1.89 2.1828 0.9758 1315742 Maybridge3_001329 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M10 compound treatment 0.317 0.00788 0.63 0.313 0.00481 0.44 0.7573 0.9834 2075903 Maybridge3_001330 Fc1ccc(c2ccc(C#N)o2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M11 compound treatment 0.318 0.00888 0.71 0.322 0.0138 1.25 1.3919 0.9645 1600433 Maybridge3_001331 O=C(Nc1ccccc1)Oc2cccc(c2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M12 compound treatment 0.324 0.0149 1.2 0.321 0.0128 1.16 1.6694 0.9999 2075904 Maybridge3_001332 Cc1ccc(cn1)c2ccn[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M13 compound treatment 0.329 0.0199 1.6 0.329 0.0208 1.89 2.4676 0.9966 1583981 Maybridge3_001333 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M14 compound treatment 0.314 0.00488 0.39 0.318 0.00981 0.89 0.9074 0.9322 2075905 Maybridge3_001334 CSCC(=O)Nc1ccc(F)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M15 compound treatment 0.35 0.0409 3.29 0.355 0.0468 4.25 5.3321 0.992 2075906 Maybridge3_001335 Cc1nc(C)c(s1)c2ccnc(n2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M16 compound treatment 0.337 0.0279 2.24 0.333 0.0248 2.25 3.1798 1.0 1207118 Maybridge3_001336 CS(=O)(=O)n1nccc1c2ccc(Oc3cccc(Cl)c3C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M17 compound treatment 0.313 0.00388 0.31 0.318 0.00981 0.89 0.8505 0.9011 2075907 Maybridge3_001337 CS/C(=N/S(=O)(=O)c1ccccc1)/NCc2c(cccc2N(C)C)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M18 compound treatment 0.323 0.0139 1.12 0.327 0.0188 1.71 1.9975 0.9789 2075908 Maybridge3_001338 CC(=O)OC1=CC(=O)CC(C1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M19 compound treatment 0.317 0.00788 0.63 0.319 0.0108 0.98 1.1424 0.9777 1151169 Maybridge3_001339 COC(CNc1cccc(Cl)c1C#N)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M20 compound treatment 0.322 0.0129 1.04 0.322 0.0138 1.25 1.6197 0.9955 1187428 Maybridge3_001340 CC(C)(C)c1ccc(cc1)C(=O)CC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M21 compound treatment 0.318 0.00888 0.71 0.32 0.0118 1.07 1.2635 0.9806 2075909 Maybridge3_001341 CC1SCC(CS1)NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M22 compound treatment 0.319 0.00988 0.8 0.318 0.00981 0.89 1.1921 0.9984 2075910 Maybridge3_001342 Nc1nccc(n1)c2cccc(Cl)c2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M23 mock treatment 0.309 -1.25E-4 -0.01 0.305 -0.00319 -0.29 -0.2117 -0.7313 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 M24 positive control 0.093 -0.216 -17.4 0.09 -0.218 -19.81 -26.3107 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N01 compound treatment 0.329 0.0199 1.6 0.327 0.0188 1.71 2.3392 0.9995 1119590 Maybridge3_001343 Oc1ccccc1c2cncn2Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N02 compound treatment 0.334 0.0249 2.0 0.326 0.0178 1.62 2.5597 0.9944 2075911 Maybridge3_001344 CCOC(=O)c1ccc(/N=C\2/NC3(CCCCC3)C(=C)S2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N03 compound treatment 0.327 0.0179 1.44 0.323 0.0148 1.34 1.9686 0.9994 2075912 Maybridge3_001345 CCC(=O)Nc1cccc(c1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N04 compound treatment 0.328 0.0189 1.52 0.328 0.0198 1.8 2.3464 0.9965 1315287 Maybridge3_001346 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N05 compound treatment 0.324 0.0149 1.2 0.324 0.0158 1.44 1.8619 0.996 1514026 Maybridge3_001347 CC1N(CCc2sccc12)S(=O)(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N06 compound treatment 0.341 0.0319 2.57 0.347 0.0388 3.52 4.3062 0.9879 2075913 Maybridge3_001348 O=c1nc([nH]c2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N07 compound treatment 0.323 0.0139 1.12 0.334 0.0258 2.34 2.4468 0.9426 1732031 Maybridge3_001349 O=C(Nc1ccccc1C(=O)Nc2cccnc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N08 compound treatment 0.32 0.0109 0.88 0.325 0.0168 1.53 1.6983 0.9652 1287544 Maybridge3_001350 COc1ccc(cc1)C(=C(SC)SC)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N09 compound treatment 0.33 0.0209 1.68 0.339 0.0308 2.8 3.1663 0.9703 2075914 Maybridge3_001351 N/N=C(\N)/SCc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N10 compound treatment 0.324 0.0149 1.2 0.325 0.0168 1.53 1.9261 0.9928 1230204 Maybridge3_001352 CCOc1cc(nc(N)n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N11 compound treatment 0.329 0.0199 1.6 0.338 0.0298 2.71 3.0452 0.9686 1455493 Maybridge3_001353 CNc1ccc(Cl)cc1C(=O)NCCc2ccc(OC)c(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N12 compound treatment 0.344 0.0349 2.81 0.35 0.0418 3.8 4.6696 0.989 1082548 Maybridge3_001354 Clc1ccc(cc1)c2cc(=S)ss2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N13 compound treatment 0.322 0.0129 1.04 0.322 0.0138 1.25 1.6197 0.9955 1452031 Maybridge3_001355 Cc1c(C)c(C)c(CCN)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N14 compound treatment 0.312 0.00288 0.23 0.318 0.00981 0.89 0.7935 0.8623 2075915 Maybridge3_001356 O=C(CC(C(C#N)C#N)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N15 compound treatment 0.321 0.0119 0.96 0.327 0.0188 1.71 1.8837 0.9624 1536665 Maybridge3_001357 O=C(NCc1cccnc1)c2nc3ccccc3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N16 compound treatment 0.335 0.0259 2.08 0.322 0.0138 1.25 2.3599 0.9705 2075916 Maybridge3_001358 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N17 compound treatment 0.375 0.0659 5.3 0.367 0.0588 5.34 7.5259 1.0 2075917 Maybridge3_001359 COc1ccc(C/N=C/c2cc(Cl)cc(Cl)c2O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N18 compound treatment 0.318 0.00888 0.71 0.321 0.0128 1.16 1.3277 0.9727 2075918 Maybridge3_001360 CSc1nc2ccnn2c(=O)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N19 compound treatment 0.327 0.0179 1.44 0.325 0.0168 1.53 2.0969 0.9996 2075919 Maybridge3_001361 COC(=O)CSc1nnc([nH]1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N20 compound treatment 0.323 0.0139 1.12 0.322 0.0138 1.25 1.6766 0.9983 1716607 Maybridge3_001362 Cn1cc(Br)c(NC(=O)c2ccc(Cl)c(Cl)c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N21 compound treatment 0.342 0.0329 2.65 0.348 0.0398 3.61 4.4273 0.9883 1729999 Maybridge3_001363 CCOC(=O)c1sc2ccc(NC(=O)C)cc2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N22 compound treatment 0.335 0.0259 2.08 0.353 0.0448 4.07 4.3496 0.9517 2075920 Maybridge3_001364 NC(=O)c1sccc1NC(=O)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N23 mock treatment 0.312 0.00288 0.23 0.31 0.00181 0.16 0.28 0.986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 N24 positive control 0.092 -0.217 -17.48 0.09 -0.218 -19.81 -26.3677 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O01 compound treatment 0.361 0.0519 4.18 0.357 0.0488 4.43 6.0868 0.9996 2075921 Maybridge3_001365 Cc1nn(C)c(O)c1C(=O)c2c(C)onc2c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O02 compound treatment 0.343 0.0339 2.73 0.337 0.0288 2.62 3.7782 0.9998 2075922 Maybridge3_001366 O/N=C/NC(=O)C1CCN(CC1)c2cccc(Cl)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O03 compound treatment 0.336 0.0269 2.16 0.333 0.0248 2.25 3.1229 0.9998 2075923 Maybridge3_001367 Cc1n[nH]c(C)c1Cc2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O04 compound treatment 0.334 0.0249 2.0 0.33 0.0218 1.98 2.8164 1.0 1218923 Maybridge3_001368 O=C(NC1CCSC1)c2ccccc2NS(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O05 compound treatment 0.329 0.0199 1.6 0.321 0.0128 1.16 1.9541 0.9877 2075924 Maybridge3_001369 NC(=N)SCc1cccc(CSC(=N)N)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O06 compound treatment 0.332 0.0229 1.84 0.326 0.0178 1.62 2.4458 0.9979 2075925 Maybridge3_001370 Clc1ccc(NC(=O)OC2CCSC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O07 compound treatment 0.309 -1.25E-4 -0.01 0.32 0.0118 1.07 0.7511 0.7004 2075926 Maybridge3_001371 Nc1oc(c(C#N)c1c2ccc(C#N)cc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O08 compound treatment 0.33 0.0209 1.68 0.327 0.0188 1.71 2.3961 1.0 1326203 Maybridge3_001372 NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O09 compound treatment 0.332 0.0229 1.84 0.333 0.0248 2.25 2.8951 0.995 1344241 Maybridge3_001373 CN(C)c1cccc(N(C)C)c1CNC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O10 compound treatment 0.351 0.0419 3.37 0.363 0.0548 4.98 5.9025 0.982 2075927 Maybridge3_001374 CS(=O)(=O)n1nccc1c2ccc(o2)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O11 compound treatment 0.331 0.0219 1.76 0.333 0.0248 2.25 2.8382 0.9926 2075928 Maybridge3_001375 O=C(Oc1cccc(c1)N2CCOCC2)c3ccc(CSC(=S)N4CCSCC4)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O12 compound treatment 0.325 0.0159 1.28 0.328 0.0198 1.8 2.1756 0.986 2075929 Maybridge3_001376 COC(=O)Nc1cc(OC)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O13 compound treatment 0.343 0.0339 2.73 0.346 0.0378 3.43 4.3559 0.9935 1218908 Maybridge3_001377 CN(C)c1cccc(N(C)C)c1CNC(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O14 compound treatment 0.326 0.0169 1.36 0.33 0.0218 1.98 2.3609 0.9831 1303697 Maybridge3_001378 CS(=O)(=O)CC(=O)NC1CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O15 compound treatment 0.327 0.0179 1.44 0.325 0.0168 1.53 2.0969 0.9996 2075930 Maybridge3_001379 Cc1n[nH]cc1c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O16 compound treatment 0.33 0.0209 1.68 0.334 0.0258 2.34 2.8454 0.9867 2075931 Maybridge3_001380 Clc1cc(CSC(=S)NCc2cccnc2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O17 compound treatment 0.327 0.0179 1.44 0.334 0.0258 2.34 2.6746 0.9726 2075932 Maybridge3_001381 CS/C(=N/C#N)/NCc1c(cccc1N(C)C)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O18 compound treatment 0.32 0.0109 0.88 0.314 0.00581 0.53 0.9923 0.9706 2075933 Maybridge3_001382 COc1ccc(Oc2cccc(Cl)c2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O19 compound treatment 0.323 0.0139 1.12 0.324 0.0158 1.44 1.805 0.9923 2075934 Maybridge3_001383 CS/C(=N\C#N)/Nc1c(C)nn(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O20 compound treatment 0.331 0.0219 1.76 0.324 0.0158 1.44 2.2605 0.9948 2075935 Maybridge3_001384 Fc1cccc(N2CCC(CC2)C#N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O21 compound treatment 0.346 0.0369 2.97 0.339 0.0308 2.8 4.0774 0.9996 2075936 Maybridge3_001385 CC1=C(OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)C(=O)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O22 compound treatment 0.327 0.0179 1.44 0.329 0.0208 1.89 2.3537 0.991 2075937 Maybridge3_001386 O=S(=O)(c1ccccc1)c2ccc(cc2)c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O23 mock treatment 0.32 0.0109 0.88 0.315 0.00681 0.62 1.0565 0.9855 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 O24 positive control 0.093 -0.216 -17.4 0.091 -0.217 -19.71 -26.2465 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P01 compound treatment 0.331 0.0219 1.76 0.331 0.0228 2.07 2.7098 0.9968 2075938 Maybridge3_001387 CC1N(CCc2sccc12)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P02 compound treatment 0.325 0.0159 1.28 0.325 0.0168 1.53 1.983 0.9961 2075939 Maybridge3_001388 COc1ccccc1/N=C/2\NC3(CCCCC3)C(=C)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P03 compound treatment 0.323 0.0139 1.12 0.331 0.0228 2.07 2.2543 0.9581 1378845 Maybridge3_001389 O=S(=O)(Nc1ccc(cc1)c2cnco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P04 compound treatment 0.317 0.00788 0.63 0.319 0.0108 0.98 1.1424 0.9777 1403222 Maybridge3_001390 CC1CN(CCC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)CC(C)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P05 compound treatment 0.337 0.0279 2.24 0.329 0.0208 1.89 2.9231 0.9963 1714399 Maybridge3_001391 NC(=O)c1c(N)c(sc1Nc2ccccc2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P06 compound treatment 0.328 0.0189 1.52 0.325 0.0168 1.53 2.1539 1.0 2075940 Maybridge3_001392 Fc1ccc(cc1)S(=O)(=O)Nc2ccc(F)c(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P07 compound treatment 0.332 0.0229 1.84 0.359 0.0508 4.61 4.5639 0.9189 1234015 Maybridge3_001393 O=C(Nc1nncs1)c2ccccc2NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P08 compound treatment 0.32 0.0109 0.88 0.322 0.0138 1.25 1.5058 0.9846 2075941 Maybridge3_001394 CN(C)CC1=C(Cl)c2ccccc2S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P09 compound treatment 0.238 -0.0711 -5.73 0.259 -0.0492 -4.46 -7.207 -0.9924 2075942 Maybridge3_001395 O=C/1/C(=C/c2cccs2)/CC\C1=C/c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P10 compound treatment 0.312 0.00288 0.23 0.315 0.00681 0.62 0.601 0.9101 2075943 Maybridge3_001396 CSc1cc(nc(n1)c2ccc(Cl)cc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P11 compound treatment 0.316 0.00688 0.55 0.314 0.00581 0.53 0.7645 0.9997 2075944 Maybridge3_001397 Cc1ccc(CSC2=NCCCN2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P12 compound treatment 0.568 0.259 20.85 0.569 0.261 23.67 31.4808 0.998 2075945 Maybridge3_001398 O=C1/C(=C/c2ccc[nH]2)/Cc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P13 compound treatment 0.303 -0.00612 -0.49 0.303 -0.00519 -0.47 -0.6817 -0.9997 2075946 Maybridge3_001399 N#CSCc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P14 compound treatment 0.321 0.0119 0.96 0.322 0.0138 1.25 1.5627 0.9911 2075947 Maybridge3_001400 Nc1nccc(n1)c2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P15 compound treatment 0.319 0.00988 0.8 0.322 0.0138 1.25 1.4488 0.9759 1180190 Maybridge3_001401 Oc1nc(nc2ccccc12)C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P16 compound treatment 0.321 0.0119 0.96 0.32 0.0118 1.07 1.4344 0.9984 1461261 Maybridge3_001402 CC(=O)Nc1ccsc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P17 compound treatment 0.326 0.0169 1.36 0.325 0.0168 1.53 2.04 0.9983 1713486 Maybridge3_001403 Clc1ccc(OCc2nc3ccccc3c(=O)o2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P18 compound treatment 0.315 0.00588 0.47 0.323 0.0148 1.34 1.2853 0.9017 1984555 Maybridge3_001404 CCc1cc2c(=O)[nH]cnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P19 compound treatment 0.323 0.0139 1.12 0.326 0.0178 1.62 1.9334 0.9837 2075948 Maybridge3_001405 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)N2CCC=CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P20 compound treatment 0.32 0.0109 0.88 0.323 0.0148 1.34 1.57 0.9784 1533743 Maybridge3_001406 Clc1ccc(s1)S(=O)(=O)Nc2[nH]ncc2Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P21 compound treatment 0.304 -0.00512 -0.41 0.305 -0.00319 -0.29 -0.4964 -0.9849 1290814 Maybridge3_001407 Oc1ccc(cc1)C(=O)CCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P22 compound treatment 0.323 0.0139 1.12 0.323 0.0148 1.34 1.7408 0.9958 2075949 Maybridge3_001408 NC(=O)c1sccc1NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P23 mock treatment 0.313 0.00388 0.31 0.309 8.12E-4 0.07 0.2728 0.8508 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1434 P24 positive control 0.096 -0.213 -17.16 0.092 -0.216 -19.62 -26.0115 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A01 compound treatment 0.306 -0.0121 -0.97 0.31 -0.0168 -1.52 -1.7622 -0.9766 2075950 Maybridge3_001409 NC(=O)c1sccc1NC(=O)CSCc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A02 compound treatment 0.308 -0.0101 -0.81 0.312 -0.0147 -1.34 -1.5199 -0.9711 2075951 Maybridge3_001410 COC(=O)c1sc(Br)c(Br)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A03 compound treatment 0.302 -0.0161 -1.29 0.309 -0.0177 -1.61 -2.0541 -0.9941 1345720 Maybridge3_001411 COC(=O)c1sc(cc1NS(=O)(=O)c2ccc(OC)cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A04 compound treatment 0.309 -0.00907 -0.73 0.314 -0.0127 -1.16 -1.3346 -0.9753 2075952 Maybridge3_001412 COC(=O)c1csc2c(cc(=O)[nH]c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A05 compound treatment 0.303 -0.0151 -1.21 0.308 -0.0187 -1.7 -2.0614 -0.9862 2075953 Maybridge3_001413 CCCc1nn(cc1C(=O)OCC)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A06 compound treatment 0.303 -0.0151 -1.21 0.307 -0.0198 -1.79 -2.1256 -0.9819 1670664 Maybridge3_001414 O=C(OCc1ccccc1)C2CC(=O)N2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A07 compound treatment 0.298 -0.0201 -1.62 0.305 -0.0217 -1.97 -2.5386 -0.9951 2075954 Maybridge3_001415 Cn1ncc(CO)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A08 compound treatment 0.302 -0.0161 -1.29 0.305 -0.0217 -1.97 -2.3109 -0.979 1221188 Maybridge3_001416 COCC(=O)Nc1sccc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A09 compound treatment 0.302 -0.0161 -1.29 0.319 -0.00775 -0.7 -1.4123 -0.959 2075955 Maybridge3_001417 CSC(=CC(=O)c1ccc(F)cc1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A10 compound treatment 0.296 -0.0221 -1.78 0.302 -0.0248 -2.25 -2.8451 -0.9933 2075956 Maybridge3_001418 CCOC(=O)c1cnc(Sc2ccc(Cl)cc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A11 compound treatment 0.3 -0.0181 -1.45 0.306 -0.0208 -1.88 -2.3606 -0.9919 2075957 Maybridge3_001419 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A12 compound treatment 0.302 -0.0161 -1.29 0.309 -0.0177 -1.61 -2.0541 -0.9941 2075958 Maybridge3_001420 CCOC(=O)c1cnc(SCc2ccc(C)cc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A13 compound treatment 0.301 -0.0171 -1.37 0.309 -0.0177 -1.61 -2.1111 -0.9969 2075959 Maybridge3_001421 FC(F)(F)c1c(cnn1c2ccc(Cl)cc2)C(=O)NC3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A14 compound treatment 0.299 -0.0191 -1.54 0.308 -0.0187 -1.7 -2.2891 -0.9987 1241233 Maybridge3_001422 COC(=O)c1sccc1NCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A15 compound treatment 0.308 -0.0101 -0.81 0.317 -0.00975 -0.89 -1.199 -0.999 2075960 Maybridge3_001423 COC(=O)c1sccc1OC(=O)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A16 compound treatment 0.31 -0.00807 -0.65 0.312 -0.0147 -1.34 -1.4061 -0.9448 2075961 Maybridge3_001424 Cn1ncc(Br)c1N2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A17 compound treatment 0.301 -0.0171 -1.37 0.322 -0.00475 -0.43 -1.2767 -0.8864 2075962 Maybridge3_001425 CC1=CC(=O)N(C1=O)c2cscc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A18 compound treatment 0.321 0.00293 0.24 0.325 -0.00175 -0.16 0.0547 0.1922 2075963 Maybridge3_001426 CCOC(=O)c1c(NC(=O)CSCC(=O)O)sc2CCCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A19 compound treatment 0.089 -0.229 -18.45 0.094 -0.233 -21.13 -27.9823 -0.9977 2075964 Maybridge3_001427 COC(=O)c1sccc1Oc2ccc(cc2N3C(=O)C=CC3=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A20 compound treatment 0.301 -0.0171 -1.37 0.311 -0.0158 -1.43 -1.9827 -0.9998 2075965 Maybridge3_001428 CCN(CC)c1ncnc2ccsc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A21 compound treatment 0.301 -0.0171 -1.37 0.31 -0.0168 -1.52 -2.0469 -0.9987 2075966 Maybridge3_001429 COC(=O)c1sccc1NC(=S)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A22 compound treatment 0.313 -0.00507 -0.41 0.312 -0.0147 -1.34 -1.2352 -0.8825 1252231 Maybridge3_001430 COc1cc2ncnc(NC3CCCCC3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A23 mock treatment 0.295 -0.0231 -1.86 0.31 -0.0168 -1.52 -2.3885 -0.9951 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 A24 positive control 0.08 -0.238 -19.17 0.08 -0.247 -22.4 -29.3934 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B01 compound treatment 0.334 0.0159 1.28 0.339 0.0123 1.11 1.6935 0.9975 1002465 Maybridge3_001431 COc1ncnc2n(C)ncc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B02 compound treatment 0.337 0.0189 1.52 0.343 0.0163 1.48 2.1211 0.9999 1226265 Maybridge3_001432 O=c1c(coc2ccccc12)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B03 compound treatment 0.324 0.00593 0.48 0.335 0.00825 0.75 0.8674 0.9764 1511403 Maybridge3_001433 CN1CCN(CC1)c2ncnc3n(C)ncc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B04 compound treatment 0.325 0.00693 0.56 0.334 0.00725 0.66 0.8601 0.9967 2075967 Maybridge3_001434 COC(=O)c1sccc1NC(=O)CSc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B05 compound treatment 0.319 9.33E-4 0.08 0.329 0.00225 0.2 0.1976 0.9078 1216448 Maybridge3_001435 CCc1nc2ccccc2nc1N3CCN(CC3)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B06 compound treatment 0.329 0.0109 0.88 0.341 0.0143 1.29 1.5372 0.9824 2075968 Maybridge3_001436 Fc1ccc(cc1)C(=O)CSc2nncn2c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B07 compound treatment 0.333 0.0149 1.2 0.342 0.0153 1.38 1.8291 0.9975 1233755 Maybridge3_001437 COc1ccc(cc1)S(=O)(=O)Nc2sccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B08 compound treatment 0.325 0.00693 0.56 0.334 0.00725 0.66 0.8601 0.9967 2075969 Maybridge3_001438 OC(=O)C1CCC1C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B09 compound treatment 0.337 0.0189 1.52 0.347 0.0203 1.84 2.3778 0.9957 2075970 Maybridge3_001439 Cc1ccc(Sc2ncnc3ccsc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B10 compound treatment 0.344 0.0259 2.09 0.35 0.0233 2.11 2.969 1.0 1285885 Maybridge3_001440 CCOC(=O)C1CCN(CC1)c2ncnc3c(C)csc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B11 compound treatment 0.325 0.00693 0.56 0.336 0.00925 0.84 0.9885 0.9803 2075971 Maybridge3_001441 FC(F)(F)Sc1ccc(NC(=O)n2ccc(n2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B12 compound treatment 0.299 -0.0191 -1.54 0.319 -0.00775 -0.7 -1.5831 -0.9374 2075972 Maybridge3_001442 Clc1ccc2OCC(=Cc2c1)C(=O)NC3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B13 compound treatment 0.319 9.33E-4 0.08 0.327 2.5E-4 0.02 0.0692 0.8813 2075973 Maybridge3_001443 FC(F)(F)c1ccnc(n1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B14 compound treatment 0.333 0.0149 1.2 0.345 0.0182 1.66 2.0217 0.9876 2075974 Maybridge3_001444 COC(=O)c1ccc(Oc2ncnc3scc(c4ccccc4)c23)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B15 compound treatment 0.311 -0.00707 -0.57 0.327 2.5E-4 0.02 -0.3863 -0.6784 1332924 Maybridge3_001445 OC(CNCc1ccc(Cl)c(Cl)c1)Cn2ccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B16 compound treatment 0.322 0.00393 0.32 0.336 0.00925 0.84 0.8177 0.9112 1566659 Maybridge3_001446 OC(=O)CSCC(=O)N1CCC(CC1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B17 compound treatment 0.321 0.00293 0.24 0.333 0.00625 0.57 0.5682 0.9246 1330113 Maybridge3_001447 OC(COc1ccc(Br)cc1)CN2CCN(CC2)c3nc(ns3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B18 compound treatment 0.325 0.00693 0.56 0.336 0.00925 0.84 0.9885 0.9803 1478473 Maybridge3_001448 OC(CNCc1ccco1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B19 compound treatment 0.323 0.00493 0.4 0.332 0.00525 0.48 0.6179 0.9959 2075975 Maybridge3_001449 FC(F)(F)c1cnc(CN2CCSCC2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B20 compound treatment 0.341 0.0229 1.85 0.349 0.0222 2.02 2.734 0.999 1293079 Maybridge3_001450 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCC(CC3)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B21 compound treatment 0.33 0.0119 0.96 0.338 0.0113 1.02 1.4016 0.9995 1623262 Maybridge3_001451 Oc1ccccc1C(=O)Cc2c(O)c3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B22 compound treatment 0.314 -0.00407 -0.33 0.327 2.5E-4 0.02 -0.2155 -0.6565 1647526 Maybridge3_001452 NC(=O)C1CCN(CC(O)COc2ccc(Cl)c(Cl)c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B23 mock treatment 0.32 0.00193 0.16 0.328 0.00125 0.11 0.1903 0.9879 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 B24 positive control 0.081 -0.237 -19.09 0.081 -0.246 -22.31 -29.2723 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C01 compound treatment 0.342 0.0239 1.93 0.35 0.0233 2.11 2.8551 0.999 1654093 Maybridge3_001453 CCOC(=O)c1c(C)csc1NC(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C02 compound treatment 0.363 0.0449 3.62 0.335 0.00825 0.75 3.0881 0.8357 1626680 Maybridge3_001454 CCOc1ccsc1C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C03 compound treatment 0.37 0.0519 4.18 0.37 0.0432 3.93 5.7331 0.9995 1083431 Maybridge3_001455 COC(=O)c1cc(O)c(s1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C04 compound treatment 0.305 -0.0131 -1.05 0.322 -0.00475 -0.43 -1.0489 -0.9224 2075976 Maybridge3_001456 COC(=O)c1csc2c(cc(nc12)N3CCNCC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C05 compound treatment 0.321 0.00293 0.24 0.332 0.00525 0.48 0.504 0.9476 1725420 Maybridge3_001457 CCCc1c(cnn1C)C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C06 compound treatment 0.31 -0.00807 -0.65 0.321 -0.00575 -0.52 -0.8284 -0.9941 2075977 Maybridge3_001458 COC(=O)c1scc(C)c1NC(=O)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C07 compound treatment 0.319 9.33E-4 0.08 0.336 0.00925 0.84 0.6469 0.7673 2075978 Maybridge3_001459 Cc1ccsc1/C=C/C(=O)Nc2ccccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C08 compound treatment 0.316 -0.00207 -0.17 0.323 -0.00375 -0.34 -0.3584 -0.9458 1419228 Maybridge3_001460 COC(CN(C)c1ncnc2sccc12)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C09 compound treatment 0.327 0.00893 0.72 0.337 0.0103 0.93 1.1666 0.9919 2075979 Maybridge3_001461 COC(=O)c1scc(C)c1n2c(C)ccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C10 compound treatment 0.32 0.00193 0.16 0.343 0.0163 1.48 1.1531 0.7774 2075980 Maybridge3_001462 CCOC(=O)c1cnc(Nc2ccc(C)cc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C11 compound treatment 0.327 0.00893 0.72 0.331 0.00425 0.39 0.7815 0.9573 1722933 Maybridge3_001463 Cc1csc2c(ncnc12)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C12 compound treatment 0.313 -0.00507 -0.41 0.322 -0.00475 -0.43 -0.5934 -0.9996 1149300 Maybridge3_001464 COC(=O)c1sc(OC)cc1OC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C13 compound treatment 0.344 0.0259 2.09 0.352 0.0253 2.29 3.0973 0.9989 1369853 Maybridge3_001465 CCCc1c(cnn1c2ccc(Cl)cc2)C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C14 compound treatment 0.314 -0.00407 -0.33 0.327 2.5E-4 0.02 -0.2155 -0.6565 1176229 Maybridge3_001466 COc1cc2nc[nH]c(=O)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C15 compound treatment 0.315 -0.00307 -0.25 0.327 2.5E-4 0.02 -0.1586 -0.6394 2075981 Maybridge3_001467 COC(=O)c1cnc(Sc2ccc(Cl)cc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C16 compound treatment 0.313 -0.00507 -0.41 0.327 2.5E-4 0.02 -0.2725 -0.6667 2075982 Maybridge3_001468 Cn1ncc(Br)c1NC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C17 compound treatment 0.333 0.0149 1.2 0.343 0.0163 1.48 1.8933 0.9949 1463408 Maybridge3_001469 NC(=O)c1sc(cc1NC(=O)CCC(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C18 compound treatment 0.312 -0.00607 -0.49 0.329 0.00225 0.2 -0.201 -0.3796 1324320 Maybridge3_001470 C(N1CCC(CC1)Nc2ncnc3ccsc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C19 compound treatment 0.326 0.00793 0.64 0.327 2.5E-4 0.02 0.4678 0.7318 2075983 Maybridge3_001471 Cc1csc(c1)c2nc(no2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C20 compound treatment 0.319 9.33E-4 0.08 0.335 0.00825 0.75 0.5827 0.7742 1734193 Maybridge3_001472 C=CCNc1ncnc2sc3CCCCc3c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C21 compound treatment 0.327 0.00893 0.72 0.326 -7.5E-4 -0.07 0.4605 0.6373 1609819 Maybridge3_001473 COC(=O)c1scc(C)c1NC(=O)c2cccc(C#N)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C22 compound treatment 0.317 -0.00107 -0.09 0.335 0.00825 0.75 0.4688 0.6219 1527950 Maybridge3_001474 COc1cc2ncnc(NCCO)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C23 mock treatment 0.313 -0.00507 -0.41 0.321 -0.00575 -0.52 -0.6576 -0.9926 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 C24 positive control 0.081 -0.237 -19.09 0.081 -0.246 -22.31 -29.2723 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D01 compound treatment 0.334 0.0159 1.28 0.34 0.0133 1.2 1.7577 0.9995 2075984 Maybridge3_001475 Cn1ncc2c(NCC=C)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D02 compound treatment 0.332 0.0139 1.12 0.34 0.0133 1.2 1.6438 0.9994 1348679 Maybridge3_001476 Cc1cc(Nc2cccc3OCOc32)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D03 compound treatment 0.369 0.0509 4.1 0.373 0.0462 4.2 5.8687 0.9999 1282459 Maybridge3_001477 CCc1nc2ccccc2nc1N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D04 compound treatment 0.324 0.00593 0.48 0.329 0.00225 0.2 0.4823 0.9281 2075985 Maybridge3_001478 Nc1nc(ncc1C#N)c2cnccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D05 compound treatment 0.349 0.0309 2.49 0.354 0.0273 2.47 3.5104 1.0 1316742 Maybridge3_001479 CCc1nc2ccccc2nc1N3CCN(CC3)C(=O)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D06 compound treatment 0.328 0.00993 0.8 0.336 0.00925 0.84 1.1593 0.9997 2075986 Maybridge3_001480 FC(F)(F)c1ccc(cc1)n2cnnc2SCC(=O)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D07 compound treatment 0.331 0.0129 1.04 0.345 0.0182 1.66 1.9078 0.975 2075987 Maybridge3_001481 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)Nc2sccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D08 compound treatment 0.327 0.00893 0.72 0.338 0.0113 1.02 1.2308 0.9853 1222912 Maybridge3_001482 Cc1cc(N2CCN(CC2)C(=O)C3CCC3C(=O)O)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D09 compound treatment 0.328 0.00993 0.8 0.343 0.0163 1.48 1.6086 0.9587 2075988 Maybridge3_001483 COC(=O)c1c(C)sc2c(cc(OC)nc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D10 compound treatment 0.327 0.00893 0.72 0.337 0.0103 0.93 1.1666 0.9919 1310044 Maybridge3_001484 Cc1csc2c(ncnc12)N3CCC(CC3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D11 compound treatment 0.325 0.00693 0.56 0.333 0.00625 0.57 0.7959 1.0 2075989 Maybridge3_001485 FC(F)(F)c1ccn(CC(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D12 compound treatment 0.353 0.0349 2.81 0.352 0.0253 2.29 3.6098 0.9948 1581875 Maybridge3_001486 Cc1ccc(cc1)c2csc3ncnc(N4CCC(O)CC4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D13 compound treatment 0.324 0.00593 0.48 0.336 0.00925 0.84 0.9316 0.9643 2075990 Maybridge3_001487 OC(COc1ccc(cn1)C(F)(F)F)CSc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D14 compound treatment 0.255 -0.0631 -5.08 0.278 -0.0488 -4.43 -6.7201 -0.9976 1307607 Maybridge3_001488 C(Cc1ccccc1)Nc2nnns2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D15 compound treatment 0.317 -0.00107 -0.09 0.327 2.5E-4 0.02 -0.0447 -0.503 1632354 Maybridge3_001489 Nc1ccccc1SCC(O)Cn2ccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D16 compound treatment 0.324 0.00593 0.48 0.333 0.00625 0.57 0.739 0.9964 1634284 Maybridge3_001490 OC(=O)COCC(=O)N1CCC(CC1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D17 compound treatment 0.33 0.0119 0.96 0.354 0.0273 2.47 2.4285 0.9152 2075991 Maybridge3_001491 OC(COc1cccc(c1)C(F)(F)F)CN2CCN(CC2)c3nc(ns3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D18 compound treatment 0.324 0.00593 0.48 0.333 0.00625 0.57 0.739 0.9964 1208214 Maybridge3_001492 NC(=O)C1CCN(CC(O)c2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D19 compound treatment 0.331 0.0129 1.04 0.331 0.00425 0.39 1.0092 0.9087 2075992 Maybridge3_001493 FC(F)(F)c1cnc(COc2ccc(C#N)cc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D20 compound treatment 0.322 0.00393 0.32 0.338 0.0113 1.02 0.946 0.8848 2075993 Maybridge3_001494 Cc1nc(ccc1C(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D21 compound treatment 0.342 0.0239 1.93 0.352 0.0253 2.29 2.9835 0.9963 2075994 Maybridge3_001495 Clc1ccc(s1)c2csc(n2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D22 compound treatment 0.337 0.0189 1.52 0.345 0.0182 1.66 2.2495 0.9991 2075995 Maybridge3_001496 OC(CN1CCN(CC1)c2ccc(cn2)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D23 mock treatment 0.318 -6.67E-5 -0.01 0.328 0.00125 0.11 0.0764 0.6729 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 D24 positive control 0.083 -0.235 -18.93 0.083 -0.244 -22.13 -29.03 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E01 compound treatment 0.358 0.0399 3.22 0.373 0.0462 4.2 5.2424 0.9913 2075996 Maybridge3_001497 CSC(=C(C#N)c1nc2ccccc2s1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E02 compound treatment 0.323 0.00493 0.4 0.334 0.00725 0.66 0.7462 0.9708 2075997 Maybridge3_001498 CCC(=O)Nc1ccsc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E03 compound treatment 0.334 0.0159 1.28 0.342 0.0153 1.38 1.8861 0.9993 1151693 Maybridge3_001499 COC(=O)c1sc(cc1NC(=O)CC#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E04 compound treatment 0.321 0.00293 0.24 0.331 0.00425 0.39 0.4398 0.9723 2075998 Maybridge3_001500 CN(C)c1cc(nc(N(C)C)c1C#N)N2CCNCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E05 compound treatment 0.39 0.0719 5.79 0.397 0.0703 6.38 8.6049 0.9988 2075999 Maybridge3_001501 CSC(=CC(=O)c1ccncc1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E06 compound treatment 0.319 9.33E-4 0.08 0.328 0.00125 0.11 0.1334 0.98 1231689 Maybridge3_001502 COC(=O)c1scc(C)c1NC(=O)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E07 compound treatment 0.329 0.0109 0.88 0.336 0.00925 0.84 1.2163 0.9997 1506674 Maybridge3_001503 Cc1ccc(cc1)S(=O)(=O)Nc2cc(sc2C(=O)N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E08 compound treatment 0.342 0.0239 1.93 0.345 0.0182 1.66 2.5342 0.9972 1236817 Maybridge3_001504 Cc1ccc(cc1)C(=O)N2CCN(CC2)Sc3ncnc4sccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E09 compound treatment 0.324 0.00593 0.48 0.331 0.00425 0.39 0.6106 0.9944 2076000 Maybridge3_001505 Clc1ccsc1C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E10 compound treatment 0.309 -0.00907 -0.73 0.338 0.0113 1.02 0.2058 0.164 2076001 Maybridge3_001506 CCOC(=O)c1cnc(SCc2ccc(Cl)cc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E11 compound treatment 0.322 0.00393 0.32 0.336 0.00925 0.84 0.8177 0.9112 1703436 Maybridge3_001507 Cc1csc2c(NCCc3ccccn3)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E12 compound treatment 0.313 -0.00507 -0.41 0.33 0.00325 0.3 -0.0799 -0.1587 1417185 Maybridge3_001508 COC(=O)c1sc(OC)cc1OC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E13 compound treatment 0.321 0.00293 0.24 0.331 0.00425 0.39 0.4398 0.9723 2076002 Maybridge3_001509 COc1ncnc2c(C)csc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E14 compound treatment 0.334 0.0159 1.28 0.34 0.0133 1.2 1.7577 0.9995 1709899 Maybridge3_001510 Cc1csc(NC(=O)c2ccco2)c1C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E15 compound treatment 0.361 0.0429 3.46 0.356 0.0293 2.66 4.3221 0.9915 2076003 Maybridge3_001511 CC1CN(CC(C)O1)c2ncc(C(=O)OCc3ccccc3)c(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E16 compound treatment 0.325 0.00693 0.56 0.33 0.00325 0.3 0.6034 0.9555 2076004 Maybridge3_001512 Cn1ncc(Br)c1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E17 compound treatment 0.326 0.00793 0.64 0.334 0.00725 0.66 0.9171 0.9999 2076005 Maybridge3_001513 FC(F)(F)c1nc(Sc2ccccn2)ncc1C(=O)OCC3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E18 compound treatment 0.329 0.0109 0.88 0.362 0.0352 3.2 2.8851 0.8694 2076006 Maybridge3_001514 COC(=O)CSc1ncnc2ccsc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E19 compound treatment 0.332 0.0139 1.12 0.334 0.00725 0.66 1.2587 0.9677 1525253 Maybridge3_001515 COC(=O)c1[nH]c2cscc2c(=O)c1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E20 compound treatment 0.326 0.00793 0.64 0.334 0.00725 0.66 0.9171 0.9999 2076007 Maybridge3_001516 C(CNc1ncnc2sc3CCCCc3c12)Cn4ccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E21 compound treatment 0.335 0.0169 1.36 0.338 0.0113 1.02 1.6863 0.9898 1269434 Maybridge3_001517 COC(=O)c1sccc1NC(=O)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E22 compound treatment 0.319 9.33E-4 0.08 0.327 2.5E-4 0.02 0.0692 0.8813 1171678 Maybridge3_001518 COc1cc2ncnc(N3CCCC3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E23 mock treatment 0.311 -0.00707 -0.57 0.324 -0.00275 -0.25 -0.5789 -0.9316 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 E24 positive control 0.084 -0.234 -18.85 0.085 -0.242 -21.94 -28.8447 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F01 compound treatment 0.329 0.0109 0.88 0.336 0.00925 0.84 1.2163 0.9997 1011408 Maybridge3_001519 CCN(CC)c1ncnc2n(C)ncc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F02 compound treatment 0.327 0.00893 0.72 0.338 0.0113 1.02 1.2308 0.9853 1431486 Maybridge3_001520 COC(=O)c1sccc1S(=O)(=O)Nc2ncc(C)cc2Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F03 compound treatment 0.359 0.0409 3.3 0.363 0.0362 3.29 4.6575 1.0 1497965 Maybridge3_001521 CCc1nc2ccccc2nc1N3CCN(CC3)C(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F04 compound treatment 0.321 0.00293 0.24 0.337 0.0103 0.93 0.8249 0.8594 2076008 Maybridge3_001522 FC(F)(F)c1ccc(cc1)c2noc(CNS(=O)(=O)c3cccs3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F05 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 2076009 Maybridge3_001523 Cc1ccc(SC(=O)c2cnn(C)c2n3cccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F06 compound treatment 0.321 0.00293 0.24 0.334 0.00725 0.66 0.6324 0.9044 2076010 Maybridge3_001524 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F07 compound treatment 0.333 0.0149 1.2 0.343 0.0163 1.48 1.8933 0.9949 1589615 Maybridge3_001525 OC(=O)CCC(=O)Nc1sccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F08 compound treatment 0.335 0.0169 1.36 0.343 0.0163 1.48 2.0072 0.9992 2076011 Maybridge3_001526 Cc1ccc(C)n1c2cc(C)ccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F09 compound treatment 0.333 0.0149 1.2 0.35 0.0233 2.11 2.3426 0.9644 1103409 Maybridge3_001527 OC(=O)CNC(=O)OCC1c2ccccc2-c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F10 compound treatment 0.337 0.0189 1.52 0.35 0.0233 2.11 2.5704 0.9873 1406399 Maybridge3_001528 CCOC(=O)C1CCN(CC1)c2ncnc3scc(C)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F11 compound treatment 0.326 0.00793 0.64 0.331 0.00425 0.39 0.7245 0.9708 2076012 Maybridge3_001529 FC(F)(F)c1ccn(CC(=O)Nc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F12 compound treatment 0.323 0.00493 0.4 0.336 0.00925 0.84 0.8746 0.9416 1167269 Maybridge3_001530 OC(=O)CSCC(=O)Nc1cccc(F)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F13 compound treatment 0.322 0.00393 0.32 0.338 0.0113 1.02 0.946 0.8848 2076013 Maybridge3_001531 Nc1ccccc1SCC(O)COc2cccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F14 compound treatment 0.336 0.0179 1.44 0.349 0.0222 2.02 2.4493 0.9865 2076014 Maybridge3_001532 Cc1nc(cs1)c2cc3cc(Cl)ccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F15 compound treatment 0.333 0.0149 1.2 0.346 0.0193 1.75 2.0859 0.9834 2076015 Maybridge3_001533 FC(F)(F)c1ccn(n1)c2ccc(NC(=O)c3cccs3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F16 compound treatment 0.335 0.0169 1.36 0.346 0.0193 1.75 2.1998 0.9925 1600775 Maybridge3_001534 OC(=O)CC1(CC(=O)N2CCC(CC2)n3cccc3)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F17 compound treatment 0.181 -0.137 -11.04 0.196 -0.131 -11.87 -16.1969 -0.9993 2076016 Maybridge3_001535 FC(F)(F)c1ccnc(SC(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F18 compound treatment 0.337 0.0189 1.52 0.349 0.0222 2.02 2.5062 0.9904 1411549 Maybridge3_001536 NC(=O)C1CCN(Cn2cnc3ccccc23)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F19 compound treatment 0.372 0.0539 4.34 0.38 0.0532 4.83 6.4889 0.9986 2076017 Maybridge3_001537 CCOC(=O)c1cc(C(=O)OCC)c(nc1/C=C/N(C)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F20 compound treatment 0.325 0.00693 0.56 0.332 0.00525 0.48 0.7318 0.9969 1369688 Maybridge3_001538 Fc1cccc(Cl)c1CN2CCCN(CC2)S(=O)(=O)c3cccc4cccnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F21 compound treatment 0.331 0.0129 1.04 0.338 0.0113 1.02 1.4585 1.0 1259217 Maybridge3_001539 COC(=O)Cc1nc(NC(=O)c2ccccc2)sc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F22 compound treatment 0.319 9.33E-4 0.08 0.331 0.00425 0.39 0.3259 0.8293 1513795 Maybridge3_001540 OC(CN1CCC(O)(CC1)c2ccc(Cl)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F23 mock treatment 0.314 -0.00407 -0.33 0.327 2.5E-4 0.02 -0.2155 -0.6565 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 F24 positive control 0.084 -0.234 -18.85 0.085 -0.242 -21.94 -28.8447 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G01 compound treatment 0.336 0.0179 1.44 0.338 0.0113 1.02 1.7432 0.9856 1371497 Maybridge3_001541 CSc1cc(nc(c1)c2ccncc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G02 compound treatment 0.321 0.00293 0.24 0.333 0.00625 0.57 0.5682 0.9246 2076018 Maybridge3_001542 CC(C)(C)c1cc(/N=C/c2ccc(O)cc2)c(C#N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G03 compound treatment 0.318 -6.67E-5 -0.01 0.328 0.00125 0.11 0.0764 0.6729 2076019 Maybridge3_001543 CCOC(=O)c1cn(nc1C(F)(F)F)S(=O)(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G04 compound treatment 0.323 0.00493 0.4 0.335 0.00825 0.75 0.8104 0.956 2076020 Maybridge3_001544 COC(=O)c1scc(C)c1NC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G05 compound treatment 0.381 0.0629 5.07 0.391 0.0643 5.83 7.7074 0.9976 2076021 Maybridge3_001545 CSC(=CC(=O)c1ccccn1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G06 compound treatment 0.322 0.00393 0.32 0.336 0.00925 0.84 0.8177 0.9112 2076022 Maybridge3_001546 COC(=O)c1ccsc1N2C(=O)C=C(C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G07 compound treatment 0.33 0.0119 0.96 0.339 0.0123 1.11 1.4658 0.9974 2076023 Maybridge3_001547 Cn1ncc(COC(=O)Nc2c(Cl)cccc2Cl)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G08 compound treatment 0.32 0.00193 0.16 0.335 0.00825 0.75 0.6396 0.8362 2076024 Maybridge3_001548 S(c1ccccc1)c2ncnc3sccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G09 compound treatment 0.324 0.00593 0.48 0.34 0.0133 1.2 1.1883 0.9182 2076025 Maybridge3_001549 COC(=O)c1scc(C)c1NC(=O)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G10 compound treatment 0.351 0.0329 2.65 0.36 0.0333 3.02 4.0094 0.9979 2076026 Maybridge3_001550 CCOC(=O)c1cnc(Sc2ccccc2N)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G11 compound treatment 0.32 0.00193 0.16 0.328 0.00125 0.11 0.1903 0.9879 2076027 Maybridge3_001551 CN(C)c1ncnc2c(C)csc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G12 compound treatment 0.348 0.0299 2.41 0.364 0.0372 3.38 4.0953 0.9862 1557528 Maybridge3_001552 CC(C)Cc1ccc(cc1)c2cc(N)c(s2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G13 compound treatment 0.334 0.0159 1.28 0.343 0.0163 1.48 1.9503 0.9976 2076028 Maybridge3_001553 CCOC(=O)c1ccc(cc1)n2c(CC)nc3c(C)csc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G14 compound treatment 0.334 0.0159 1.28 0.348 0.0213 1.93 2.2712 0.9804 2076029 Maybridge3_001554 Cc1csc(N2C(=O)C=CC2=O)c1C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G15 compound treatment 0.315 -0.00307 -0.25 0.336 0.00925 0.84 0.4191 0.4789 2076030 Maybridge3_001555 COC(=O)c1cnc(Sc2ccccn2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G16 compound treatment 0.321 0.00293 0.24 0.335 0.00825 0.75 0.6966 0.8871 2076031 Maybridge3_001556 Cc1ccc(SCC(=O)Nc2c(Br)cnn2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G17 compound treatment 0.318 -6.67E-5 -0.01 0.336 0.00925 0.84 0.5899 0.7026 2076032 Maybridge3_001557 COC(=O)c1sccc1Oc2ccc(cc2N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G18 compound treatment 0.326 0.00793 0.64 0.34 0.0133 1.2 1.3022 0.9562 2076033 Maybridge3_001558 C(CNc1ncnc2ccsc12)Cn3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G19 compound treatment 0.329 0.0109 0.88 0.341 0.0143 1.29 1.5372 0.9824 1549025 Maybridge3_001559 COC(=O)c1c(C)scc1NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G20 compound treatment 0.327 0.00893 0.72 0.334 0.00725 0.66 0.974 0.999 1637056 Maybridge3_001560 CC(C)Nc1ncnc2ccsc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G21 compound treatment 0.324 0.00593 0.48 0.332 0.00525 0.48 0.6748 1.0 2076034 Maybridge3_001561 COC(=O)c1scc(C)c1NC(=S)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G22 compound treatment 0.326 0.00793 0.64 0.33 0.00325 0.3 0.6603 0.9384 1193958 Maybridge3_001562 COc1cc2ncnc(N3CCN(C)CC3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G23 mock treatment 0.32 0.00193 0.16 0.329 0.00225 0.2 0.2545 0.991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 G24 positive control 0.086 -0.232 -18.69 0.086 -0.241 -21.85 -28.6666 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H01 compound treatment 0.33 0.0119 0.96 0.336 0.00925 0.84 1.2732 0.9977 1333518 Maybridge3_001563 Cn1ncc2c(NC3CCCCC3)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H02 compound treatment 0.347 0.0289 2.33 0.356 0.0293 2.66 3.5249 0.9979 2076035 Maybridge3_001564 Clc1ccc2oc(cc2c1)C(=O)CNc3ccc4OCCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H03 compound treatment 0.33 0.0119 0.96 0.331 0.00425 0.39 0.9523 0.9196 2076036 Maybridge3_001565 Cn1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H04 compound treatment 0.333 0.0149 1.2 0.341 0.0143 1.29 1.765 0.9993 2076037 Maybridge3_001566 CCOC(=O)c1c(C)csc1NC(=O)CSCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H05 compound treatment 0.33 0.0119 0.96 0.341 0.0143 1.29 1.5941 0.9893 2076038 Maybridge3_001567 CC(C)NC(=O)c1cnn(C)c1n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H06 compound treatment 0.327 0.00893 0.72 0.331 0.00425 0.39 0.7815 0.9573 2076039 Maybridge3_001568 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)c2cccc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H07 compound treatment 0.327 0.00893 0.72 0.342 0.0153 1.38 1.4875 0.9535 2076040 Maybridge3_001569 Cc1csc2nc(CN3CCOCC3)[nH]c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H08 compound treatment 0.317 -0.00107 -0.09 0.333 0.00625 0.57 0.3404 0.5933 1561566 Maybridge3_001570 Fc1ccc(cc1)S(=O)(=O)Nc2cccc(Oc3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H09 compound treatment 0.328 0.00993 0.8 0.338 0.0113 1.02 1.2877 0.9927 1416686 Maybridge3_001571 Nc1ncncc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H10 compound treatment 0.332 0.0139 1.12 0.349 0.0222 2.02 2.2215 0.9615 1454169 Maybridge3_001572 Cc1csc2ncnc(N3CCC(CC3)C(=O)O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H11 compound treatment 0.317 -0.00107 -0.09 0.332 0.00525 0.48 0.2762 0.5705 2076041 Maybridge3_001573 CC(C)(C)NC(=O)Cn1ccc(n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H12 compound treatment 0.328 0.00993 0.8 0.337 0.0103 0.93 1.2235 0.9972 1457035 Maybridge3_001574 OC(=O)CCCC(=O)Nc1cccc(F)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H13 compound treatment 0.325 0.00693 0.56 0.341 0.0143 1.29 1.3094 0.9294 2076042 Maybridge3_001575 CC(C)NCC(O)Cn1ccc(n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H14 compound treatment 0.322 0.00393 0.32 0.337 0.0103 0.93 0.8819 0.8973 2076043 Maybridge3_001576 Clc1cccc(Nc2nnns2)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H15 compound treatment 0.333 0.0149 1.2 0.332 0.00525 0.48 1.1873 0.9179 2076044 Maybridge3_001577 Cc1noc(C)c1C(=O)Nc2ccc(cc2)n3ccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H16 compound treatment 0.323 0.00493 0.4 0.335 0.00825 0.75 0.8104 0.956 2076045 Maybridge3_001578 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCC(CC2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H17 compound treatment 0.172 -0.146 -11.76 0.183 -0.144 -13.05 -17.5438 -0.9987 2076046 Maybridge3_001579 Cc1noc(C)c1C(=O)Sc2nccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H18 compound treatment 0.324 0.00593 0.48 0.334 0.00725 0.66 0.8032 0.9876 1324200 Maybridge3_001580 CC(C)(C)c1cc2ncnc(NCc3ccc4OCOc4c3)c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H19 compound treatment 0.335 0.0169 1.36 0.342 0.0153 1.38 1.943 1.0 2076047 Maybridge3_001581 CCOC(=O)c1cc2c(O)nccc2nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H20 compound treatment 0.307 -0.0111 -0.89 0.324 -0.00275 -0.25 -0.8067 -0.8716 2076048 Maybridge3_001582 CN(C)c1ccc(cc1)n2nnnc2SCc3cc(F)cc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H21 compound treatment 0.308 -0.0101 -0.81 0.323 -0.00375 -0.34 -0.8139 -0.9257 2076049 Maybridge3_001583 Clc1ccc(s1)c2csc(n2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H22 compound treatment 0.326 0.00793 0.64 0.335 0.00825 0.75 0.9813 0.9969 2076050 Maybridge3_001584 FC(F)(F)c1ccc(nc1)N2CCN(Cn3nnc4ccccc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H23 mock treatment 0.321 0.00293 0.24 0.332 0.00525 0.48 0.504 0.9476 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 H24 positive control 0.087 -0.231 -18.61 0.087 -0.24 -21.76 -28.5455 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I01 compound treatment 0.318 -6.67E-5 -0.01 0.326 -7.5E-4 -0.07 -0.0519 -0.7605 2076051 Maybridge3_001585 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I02 compound treatment 0.357 0.0389 3.14 0.359 0.0323 2.93 4.2869 0.9994 2076052 Maybridge3_001586 CCOc1ccsc1c2nnc(o2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I03 compound treatment 0.331 0.0129 1.04 0.344 0.0173 1.57 1.8436 0.9804 2076053 Maybridge3_001587 CCCc1nn(cc1C(=O)OCC)S(=O)(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I04 compound treatment 0.324 0.00593 0.48 0.337 0.0103 0.93 0.9957 0.952 2076054 Maybridge3_001588 Cn1cc(Br)c(NC(=O)/C=C/C(=O)O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I05 compound treatment 0.328 0.00993 0.8 0.344 0.0173 1.57 1.6728 0.9514 2076055 Maybridge3_001589 CSc1cc(nc(c1)C(C)(C)C)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I06 compound treatment 0.326 0.00793 0.64 0.339 0.0123 1.11 1.238 0.9654 2076056 Maybridge3_001590 Cc1ccc(Sc2ncnc3sccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I07 compound treatment 0.321 0.00293 0.24 0.345 0.0182 1.66 1.3384 0.7998 2076057 Maybridge3_001591 NC(=O)c1sc(cc1NC(=O)C(F)(F)F)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I08 compound treatment 0.335 0.0169 1.36 0.34 0.0133 1.2 1.8147 0.998 1713558 Maybridge3_001592 CCC(C)Nc1ncnc2sccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I09 compound treatment 0.322 0.00393 0.32 0.334 0.00725 0.66 0.6893 0.9438 2076058 Maybridge3_001593 Cc1csc(c1Cl)c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I10 compound treatment 0.323 0.00493 0.4 0.34 0.0133 1.2 1.1314 0.8932 2076059 Maybridge3_001594 Clc1ccc(cc1)c2nnnn2Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I11 compound treatment 0.328 0.00993 0.8 0.343 0.0163 1.48 1.6086 0.9587 1700183 Maybridge3_001595 CN(CCO)c1ncnc2c(C)csc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I12 compound treatment 0.319 9.33E-4 0.08 0.336 0.00925 0.84 0.6469 0.7673 1392540 Maybridge3_001596 Cn1nccc1NC(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I13 compound treatment 0.322 0.00393 0.32 0.337 0.0103 0.93 0.8819 0.8973 2076060 Maybridge3_001597 COC(=O)c1sccc1NS(=O)(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I14 compound treatment 0.32 0.00193 0.16 0.338 0.0113 1.02 0.8322 0.8056 2076061 Maybridge3_001598 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I15 compound treatment 0.326 0.00793 0.64 0.34 0.0133 1.2 1.3022 0.9562 2076062 Maybridge3_001599 Cc1csc(c1)C(=O)Nc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I16 compound treatment 0.327 0.00893 0.72 0.336 0.00925 0.84 1.1024 0.997 2076063 Maybridge3_001600 COc1cc2ncnc(Sc3ccccn3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I17 compound treatment 0.334 0.0159 1.28 0.344 0.0173 1.57 2.0144 0.9951 1306500 Maybridge3_001601 COc1ccc(cc1OC)C(C#N)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I18 compound treatment 0.329 0.0109 0.88 0.34 0.0133 1.2 1.473 0.9882 2076064 Maybridge3_001602 C(CNc1ncnc2ccsc12)CN3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I19 compound treatment 0.335 0.0169 1.36 0.341 0.0143 1.29 1.8788 0.9997 2076065 Maybridge3_001603 COC(=O)c1c(C)scc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I20 compound treatment 0.328 0.00993 0.8 0.335 0.00825 0.75 1.0951 0.9995 1528852 Maybridge3_001604 C(Cc1ccccc1)Nc2ncnc3ccsc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I21 compound treatment 0.324 0.00593 0.48 0.343 0.0163 1.48 1.3809 0.8906 2076066 Maybridge3_001605 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(NC(=O)C(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I22 compound treatment 0.332 0.0139 1.12 0.342 0.0153 1.38 1.7722 0.9946 2076067 Maybridge3_001606 CCOc1ncnc2cc(OC)c(OC)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I23 mock treatment 0.321 0.00293 0.24 0.331 0.00425 0.39 0.4398 0.9723 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 I24 positive control 0.087 -0.231 -18.61 0.087 -0.24 -21.76 -28.5455 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J01 compound treatment 0.328 0.00993 0.8 0.336 0.00925 0.84 1.1593 0.9997 1734498 Maybridge3_001607 CC(C)Nc1ncnc2n(C)ncc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J02 compound treatment 0.328 0.00993 0.8 0.34 0.0133 1.2 1.4161 0.9804 1212602 Maybridge3_001608 OC(=O)CSCC(=O)Nc1ccc2OCCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J03 compound treatment 0.32 0.00193 0.16 0.331 0.00425 0.39 0.3829 0.9203 1214364 Maybridge3_001609 COc1cccc(NC(=O)c2cnn(C)c2n3cccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J04 compound treatment 0.359 0.0409 3.3 0.36 0.0333 3.02 4.4649 0.999 1517146 Maybridge3_001610 Cc1onc(c1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J05 compound treatment 0.33 0.0119 0.96 0.338 0.0113 1.02 1.4016 0.9995 1405010 Maybridge3_001611 Cn1ncc(C(=O)NC2CCCCC2)c1n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J06 compound treatment 0.334 0.0159 1.28 0.345 0.0182 1.66 2.0786 0.992 2076068 Maybridge3_001612 COC(=O)Cc1nc(NC(=O)c2cc(C)oc2C(F)(F)F)sc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J07 compound treatment 0.32 0.00193 0.16 0.342 0.0153 1.38 1.0889 0.7817 1274900 Maybridge3_001613 C1CN(CCO1)c2ncnc3ccsc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J08 compound treatment 0.32 0.00193 0.16 0.333 0.00625 0.57 0.5112 0.869 1262185 Maybridge3_001614 Fc1ccc(cc1)S(=O)(=O)Nc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J09 compound treatment 0.323 0.00493 0.4 0.338 0.0113 1.02 1.003 0.9154 2076069 Maybridge3_001615 CCN(CC)CC(O)COc1cc(ccn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J10 compound treatment 0.347 0.0289 2.33 0.361 0.0343 3.11 3.8458 0.9899 2076070 Maybridge3_001616 CC(=O)Nc1scc(C)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J11 compound treatment 0.324 0.00593 0.48 0.334 0.00725 0.66 0.8032 0.9876 2076071 Maybridge3_001617 FC(F)(F)c1ccn(CC(=O)Nc2cccc(c2)C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J12 compound treatment 0.324 0.00593 0.48 0.336 0.00925 0.84 0.9316 0.9643 2076072 Maybridge3_001618 COC(=O)c1sc(cc1Cl)S(=O)(=O)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J13 compound treatment 0.321 0.00293 0.24 0.339 0.0123 1.11 0.9533 0.8386 2076073 Maybridge3_001619 OC(CN1CCCC1)Cn2ccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J14 compound treatment 0.324 0.00593 0.48 0.33 0.00325 0.3 0.5465 0.9732 2076074 Maybridge3_001620 Fc1ccc(Nc2nnns2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J15 compound treatment 0.32 0.00193 0.16 0.335 0.00825 0.75 0.6396 0.8362 2076075 Maybridge3_001621 OC(=O)/C=C/C(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J16 compound treatment 0.325 0.00693 0.56 0.34 0.0133 1.2 1.2452 0.9391 2076076 Maybridge3_001622 FC(F)(F)c1ccc(cc1)c2noc(CNC(=O)c3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J17 compound treatment 0.324 0.00593 0.48 0.335 0.00825 0.75 0.8674 0.9764 2076077 Maybridge3_001623 FC(F)(F)c1ccnc(SCC(=O)c2ccc(Br)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J18 compound treatment 0.323 0.00493 0.4 0.33 0.00325 0.3 0.4895 0.9893 1631856 Maybridge3_001624 COc1ccccc1CNS(=O)(=O)c2cccc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J19 compound treatment 0.334 0.0159 1.28 0.34 0.0133 1.2 1.7577 0.9995 2076078 Maybridge3_001625 CCOC(=O)c1cc2ncc(cc2s1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J20 compound treatment 0.318 -6.67E-5 -0.01 0.337 0.0103 0.93 0.6541 0.703 2076079 Maybridge3_001626 CN(C)c1ccc(cc1)n2nnnc2SCc3ccc(OC(F)(F)F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J21 compound treatment 0.34 0.0219 1.77 0.345 0.0182 1.66 2.4203 0.9995 2076080 Maybridge3_001627 Cc1nc(cs1)c2nc(cs2)c3ccc(Cl)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J22 compound treatment 0.328 0.00993 0.8 0.336 0.00925 0.84 1.1593 0.9997 1494021 Maybridge3_001628 OC1(CCN(Cn2nnc3ccccc23)CC1)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J23 mock treatment 0.317 -0.00107 -0.09 0.328 0.00125 0.11 0.0195 0.137 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 J24 positive control 0.087 -0.231 -18.61 0.088 -0.239 -21.67 -28.4813 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K01 compound treatment 0.329 0.0109 0.88 0.336 0.00925 0.84 1.2163 0.9997 1728065 Maybridge3_001629 Cn1ncc(C(=O)Nc2cc(Cl)ccc2Cl)c1n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K02 compound treatment 0.331 0.0129 1.04 0.344 0.0173 1.57 1.8436 0.9804 2076081 Maybridge3_001630 Cn1nc(c2cc(sc12)C(=O)Nc3ccc(F)cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K03 compound treatment 0.324 0.00593 0.48 0.335 0.00825 0.75 0.8674 0.9764 2076082 Maybridge3_001631 CCCc1nn(cc1C(=O)OCC)C(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K04 compound treatment 0.328 0.00993 0.8 0.339 0.0123 1.11 1.3519 0.9869 2076083 Maybridge3_001632 NC(=O)c1sc(cc1NC(=O)/C=C/C(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K05 compound treatment 0.316 -0.00207 -0.17 0.331 0.00425 0.39 0.1551 0.3692 2076084 Maybridge3_001633 Clc1ccc(SC(=O)N/C=C/c2ccsc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K06 compound treatment 0.33 0.0119 0.96 0.338 0.0113 1.02 1.4016 0.9995 1696268 Maybridge3_001634 COC(=O)c1ccsc1NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K07 compound treatment 0.354 0.0359 2.89 0.364 0.0372 3.38 4.437 0.997 2076085 Maybridge3_001635 NC(=O)c1sc(cc1N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K08 compound treatment 0.32 0.00193 0.16 0.34 0.0133 1.2 0.9605 0.792 1256908 Maybridge3_001636 Clc1ccc(CCNc2ncnc3sccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K09 compound treatment 0.316 -0.00207 -0.17 0.334 0.00725 0.66 0.3477 0.5122 2076086 Maybridge3_001637 Clc1ccsc1c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K10 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 2076087 Maybridge3_001638 Clc1cc(Cl)cc(c1)c2nnnn2Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K11 compound treatment 0.325 0.00693 0.56 0.334 0.00725 0.66 0.8601 0.9967 2076088 Maybridge3_001639 Cc1csc2ncnc(Sc3ccc(Cl)cc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K12 compound treatment 0.319 9.33E-4 0.08 0.34 0.0133 1.2 0.9036 0.7498 2076089 Maybridge3_001640 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccco3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K13 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 2076090 Maybridge3_001641 FC(F)(F)Oc1ccc(NC(=O)C2CCc3ccccc3O2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K14 compound treatment 0.322 0.00393 0.32 0.341 0.0143 1.29 1.1386 0.855 2076091 Maybridge3_001642 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K15 compound treatment 0.325 0.00693 0.56 0.341 0.0143 1.29 1.3094 0.9294 1655288 Maybridge3_001643 Cc1cc(Br)c(N2C(=O)CCC2=O)c(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K16 compound treatment 0.326 0.00793 0.64 0.338 0.0113 1.02 1.1738 0.9745 1429650 Maybridge3_001644 COc1cc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K17 compound treatment 0.498 0.18 14.49 0.498 0.171 15.54 21.2372 0.9994 2076092 Maybridge3_001645 CC(=C)c1ccccc(=O)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K18 compound treatment 0.325 0.00693 0.56 0.337 0.0103 0.93 1.0527 0.9702 1557491 Maybridge3_001646 C1CCN(CC1)Nc2ncnc3ccsc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K19 compound treatment 0.329 0.0109 0.88 0.335 0.00825 0.75 1.1521 0.9968 2076093 Maybridge3_001647 COC(=O)c1c(C)scc1NS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K20 compound treatment 0.327 0.00893 0.72 0.333 0.00625 0.57 0.9098 0.9931 2076094 Maybridge3_001648 Cn1nccc1NC(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K21 compound treatment 0.325 0.00693 0.56 0.335 0.00825 0.75 0.9243 0.9895 2076095 Maybridge3_001649 FC(F)(F)c1cccc(c1)S(=O)(=O)Nc2ccsc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K22 compound treatment 0.379 0.0609 4.91 0.387 0.0602 5.47 7.3367 0.9985 2076096 Maybridge3_001650 COC(=O)c1sc(cc1N)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K23 mock treatment 0.318 -6.67E-5 -0.01 0.328 0.00125 0.11 0.0764 0.6729 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 K24 positive control 0.088 -0.23 -18.53 0.09 -0.237 -21.49 -28.296 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L01 compound treatment 0.331 0.0129 1.04 0.336 0.00925 0.84 1.3301 0.9943 1002486 Maybridge3_001651 Cn1ncc2c(NCCO)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L02 compound treatment 0.331 0.0129 1.04 0.339 0.0123 1.11 1.5227 0.9995 2076097 Maybridge3_001652 OC(=O)CCC(=O)Nc1ccc2OCCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L03 compound treatment 0.346 0.0279 2.25 0.355 0.0283 2.56 3.4038 0.9979 2076098 Maybridge3_001653 COc1cccc(/C=N/c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L04 compound treatment 0.344 0.0259 2.09 0.354 0.0273 2.47 3.2257 0.9965 1259328 Maybridge3_001654 OC1(CCN(CC1)C(=O)C2CCCCC2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L05 compound treatment 0.328 0.00993 0.8 0.34 0.0133 1.2 1.4161 0.9804 2076099 Maybridge3_001655 Cn1ncc(C(=O)NCC=C)c1n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L06 compound treatment 0.338 0.0199 1.61 0.341 0.0143 1.29 2.0497 0.9943 2076100 Maybridge3_001656 COc1ccc(Oc2ccc(c(NC(=O)C3CCC3C(=O)O)c2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L07 compound treatment 0.33 0.0119 0.96 0.344 0.0173 1.57 1.7867 0.9725 2076101 Maybridge3_001657 OC(=O)/C=C/C(=O)Nc1sccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L08 compound treatment 0.322 0.00393 0.32 0.335 0.00825 0.75 0.7535 0.9267 1247535 Maybridge3_001658 COc1ccc(NC(=O)C2CC2)cc1OC3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L09 compound treatment 0.324 0.00593 0.48 0.337 0.0103 0.93 0.9957 0.952 2076102 Maybridge3_001659 OC(CNCCc1cccs1)COc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L10 compound treatment 0.332 0.0139 1.12 0.341 0.0143 1.29 1.708 0.9975 2076103 Maybridge3_001660 Cc1csc(NC(=O)C(F)(F)F)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L11 compound treatment 0.333 0.0149 1.2 0.343 0.0163 1.48 1.8933 0.9949 2076104 Maybridge3_001661 FC(F)(F)c1ccnc(NCc2ccco2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L12 compound treatment 0.329 0.0109 0.88 0.339 0.0123 1.11 1.4088 0.9933 2076105 Maybridge3_001662 COC(=O)c1sc(cc1Cl)S(=O)(=O)Nc2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L13 compound treatment 0.327 0.00893 0.72 0.338 0.0113 1.02 1.2308 0.9853 2076106 Maybridge3_001663 OC(Cn1ccc(n1)C(F)(F)F)CS(=O)(=O)Cc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L14 compound treatment 0.359 0.0409 3.3 0.359 0.0323 2.93 4.4007 0.9982 1637018 Maybridge3_001664 OC(=O)c1ccccc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L15 compound treatment 0.332 0.0139 1.12 0.343 0.0163 1.48 1.8364 0.9909 2076107 Maybridge3_001665 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)n3ccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L16 compound treatment 0.331 0.0129 1.04 0.336 0.00925 0.84 1.3301 0.9943 1618581 Maybridge3_001666 OC(=O)c1ccccc1C(=O)N(Cc2ccccn2)Cc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L17 compound treatment 0.406 0.0879 7.08 0.412 0.0853 7.74 10.4788 0.999 1121542 Maybridge3_001667 CC(C)(C)c1ccc(cc1)c2nc(O)c(CC(=O)O)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L18 compound treatment 0.328 0.00993 0.8 0.335 0.00825 0.75 1.0951 0.9995 1234490 Maybridge3_001668 O=S(=O)(NCc1cccs1)c2cccc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L19 compound treatment 0.359 0.0409 3.3 0.367 0.0403 3.65 4.9142 0.9987 2076108 Maybridge3_001669 CCOC(=O)c1cc2c(nccc2nc1C(F)(F)F)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L20 compound treatment 0.311 -0.00707 -0.57 0.322 -0.00475 -0.43 -0.7073 -0.9906 2076109 Maybridge3_001670 CN(C)c1ccc(cc1)n2nnnc2SCc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L21 compound treatment 0.331 0.0129 1.04 0.338 0.0113 1.02 1.4585 1.0 1433643 Maybridge3_001671 COc1ccc(C2OCCCO2)c(Cl)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L22 compound treatment 0.326 0.00793 0.64 0.334 0.00725 0.66 0.9171 0.9999 1149235 Maybridge3_001672 Cn1nc(NC(=O)C2CCC2C(=O)O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L23 mock treatment 0.323 0.00493 0.4 0.332 0.00525 0.48 0.6179 0.9959 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 L24 positive control 0.089 -0.229 -18.45 0.09 -0.237 -21.49 -28.2391 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M01 compound treatment 0.331 0.0129 1.04 0.336 0.00925 0.84 1.3301 0.9943 2076110 Maybridge3_001673 COC(=O)c1sc(cc1NC(=O)C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M02 compound treatment 0.33 0.0119 0.96 0.336 0.00925 0.84 1.2732 0.9977 1338598 Maybridge3_001674 CCOC(=O)c1cc(CC)sc1NC(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M03 compound treatment 0.323 0.00493 0.4 0.332 0.00525 0.48 0.6179 0.9959 2076111 Maybridge3_001675 CCOC(=O)c1cn(nc1C(F)(F)F)C(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M04 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 2076112 Maybridge3_001676 COC(=O)c1cnc(N)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M05 compound treatment 0.319 9.33E-4 0.08 0.326 -7.5E-4 -0.07 0.005 0.0494 2076113 Maybridge3_001677 Cc1ccc(SC(=O)N/C=C/c2ccsc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M06 compound treatment 0.323 0.00493 0.4 0.331 0.00425 0.39 0.5537 0.9999 2076114 Maybridge3_001678 CCN(CC)c1ncnc2sccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M07 compound treatment 0.167 -0.151 -12.16 0.192 -0.135 -12.23 -17.2508 -1.0 2076115 Maybridge3_001679 COC(=O)c1sccc1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M08 compound treatment 0.323 0.00493 0.4 0.337 0.0103 0.93 0.9388 0.928 1257717 Maybridge3_001680 O=C(N1CCN(CC1)c2ncnc3sccc23)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M09 compound treatment 0.323 0.00493 0.4 0.335 0.00825 0.75 0.8104 0.956 2076116 Maybridge3_001681 CCOC(=O)c1c(O)c2scc(C)c2[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M10 compound treatment 0.321 0.00293 0.24 0.328 0.00125 0.11 0.2473 0.9436 2076117 Maybridge3_001682 Nc1ncc(C(=O)OCC2CC2)c(n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M11 compound treatment 0.334 0.0159 1.28 0.34 0.0133 1.2 1.7577 0.9995 2076118 Maybridge3_001683 CSC(=CC(=O)c1ccccc1F)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M12 compound treatment 0.353 0.0349 2.81 0.354 0.0273 2.47 3.7382 0.9979 1271347 Maybridge3_001684 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M13 compound treatment 0.305 -0.0131 -1.05 0.313 -0.0138 -1.25 -1.6266 -0.9964 1448183 Maybridge3_001685 Clc1ccc(cc1)c2noc(n2)C3CCc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M14 compound treatment 0.329 0.0109 0.88 0.335 0.00825 0.75 1.1521 0.9968 1309130 Maybridge3_001686 COC(=O)c1sccc1Oc2ccc(Cl)cc2N3C(=O)CCC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M15 compound treatment 0.333 0.0149 1.2 0.341 0.0143 1.29 1.765 0.9993 2076119 Maybridge3_001687 CC1=CC(=O)N(C1=O)c2nc(cs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M16 compound treatment 0.322 0.00393 0.32 0.328 0.00125 0.11 0.3042 0.9041 2076120 Maybridge3_001688 Cn1ncc(Br)c1NC(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M17 compound treatment 0.329 0.0109 0.88 0.351 0.0243 2.2 2.179 0.9191 2076121 Maybridge3_001689 Fc1ccc(NC(=O)Cn2nnc(n2)c3cccc(c3)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M18 compound treatment 0.34 0.0219 1.77 0.346 0.0193 1.75 2.4845 1.0 1291220 Maybridge3_001690 CCOC(=O)c1c(sc2CCCCc12)N3C(=O)CSCC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M19 compound treatment 0.327 0.00893 0.72 0.33 0.00325 0.3 0.7173 0.9225 1702797 Maybridge3_001691 CCCCc1c(O)nc(N)nc1COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M20 compound treatment 0.32 0.00193 0.16 0.324 -0.00275 -0.25 -0.0664 -0.2258 1470799 Maybridge3_001692 COc1cc2ncnc(NC(C)C)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M21 compound treatment 0.324 0.00593 0.48 0.334 0.00725 0.66 0.8032 0.9876 2076122 Maybridge3_001693 Cc1cscc1NC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M22 compound treatment 0.327 0.00893 0.72 0.329 0.00225 0.2 0.6531 0.8733 1351569 Maybridge3_001694 Cn1ncc2c(ncnc12)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M23 mock treatment 0.314 -0.00407 -0.33 0.324 -0.00275 -0.25 -0.4081 -0.991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 M24 positive control 0.088 -0.23 -18.53 0.091 -0.236 -21.4 -28.2318 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N01 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 2076123 Maybridge3_001695 Cn1ncc2c(Sc3cccc4ccccc34)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N02 compound treatment 0.329 0.0109 0.88 0.337 0.0103 0.93 1.2805 0.9996 1372800 Maybridge3_001696 OC(=O)CSCC(=O)Nc1ccccc1N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N03 compound treatment 0.323 0.00493 0.4 0.336 0.00925 0.84 0.8746 0.9416 2076124 Maybridge3_001697 Cn1ncc(C(=O)Nc2cccc(F)c2)c1n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N04 compound treatment 0.355 0.0369 2.97 0.357 0.0302 2.75 4.0446 0.9992 1537276 Maybridge3_001698 COc1ccc(cc1OC)C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N05 compound treatment 0.369 0.0509 4.1 0.372 0.0452 4.11 5.8046 1.0 2076125 Maybridge3_001699 COC(=O)c1sc(cc1NS(=O)(=O)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N06 compound treatment 0.354 0.0359 2.89 0.356 0.0293 2.66 3.9235 0.9991 1552044 Maybridge3_001700 CN(C(=O)C1CCC1C(=O)O)c2nc(cs2)c3ccc(Cl)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N07 compound treatment 0.334 0.0159 1.28 0.342 0.0153 1.38 1.8861 0.9993 2076126 Maybridge3_001701 OC(=O)CSCC(=O)Nc1sccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N08 compound treatment 0.332 0.0139 1.12 0.342 0.0153 1.38 1.7722 0.9946 1694976 Maybridge3_001702 Fc1ccc(cc1)n2ncc(C#N)c2NC(=O)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N09 compound treatment 0.329 0.0109 0.88 0.343 0.0163 1.48 1.6656 0.9696 2076127 Maybridge3_001703 FC(F)(F)c1ccn(n1)C(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N10 compound treatment 0.355 0.0369 2.97 0.365 0.0382 3.47 4.5581 0.997 1140461 Maybridge3_001704 Cc1oc(cc1C(=O)Nc2ccc(F)cc2)S(=O)(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N11 compound treatment 0.342 0.0239 1.93 0.352 0.0253 2.29 2.9835 0.9963 2076128 Maybridge3_001705 FC(F)(F)c1ccnc(NCCNc2nccc(n2)C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N12 compound treatment 0.337 0.0189 1.52 0.341 0.0143 1.29 1.9927 0.9967 1385405 Maybridge3_001706 OC(=O)c1sccc1S(=O)(=O)Nc2ccccc2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N13 compound treatment 0.332 0.0139 1.12 0.337 0.0103 0.93 1.4513 0.9957 2076129 Maybridge3_001707 OC(Cn1ccc(n1)C(F)(F)F)CS(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N14 compound treatment 0.345 0.0269 2.17 0.35 0.0233 2.11 3.0259 0.9999 2076130 Maybridge3_001708 CCCCC(=O)NCc1nc(no1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N15 compound treatment 0.102 -0.216 -17.4 0.113 -0.214 -19.4 -26.0226 -0.9985 2076131 Maybridge3_001709 FC(F)(F)c1ccn(n1)c2ccc(cc2)N3C(=O)C=CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N16 compound treatment 0.327 0.00893 0.72 0.334 0.00725 0.66 0.974 0.999 1191493 Maybridge3_001710 OC(CNCc1cccs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N17 compound treatment 0.377 0.0589 4.75 0.385 0.0583 5.29 7.0945 0.9985 2076132 Maybridge3_001711 OC(=O)Cc1sc(nc1O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N18 compound treatment 0.353 0.0349 2.81 0.354 0.0273 2.47 3.7382 0.9979 1177132 Maybridge3_001712 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N19 compound treatment 0.34 0.0219 1.77 0.347 0.0203 1.84 2.5487 0.9998 2076133 Maybridge3_001713 N1C(c2cccs2)c3cccn3-c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N20 compound treatment 0.319 9.33E-4 0.08 0.328 0.00125 0.11 0.1334 0.98 2076134 Maybridge3_001714 CN(C)c1ccc(cc1)n2nnnc2SCC(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N21 compound treatment 0.325 0.00693 0.56 0.327 2.5E-4 0.02 0.4108 0.7352 1625027 Maybridge3_001715 Cc1cc(N2CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N22 compound treatment 0.337 0.0189 1.52 0.343 0.0163 1.48 2.1211 0.9999 2076135 Maybridge3_001716 Cn1nc(c(c1NC(=O)C2CCC2C(=O)O)c3ccc(Br)cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N23 mock treatment 0.32 0.00193 0.16 0.328 0.00125 0.11 0.1903 0.9879 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 N24 positive control 0.089 -0.229 -18.45 0.091 -0.236 -21.4 -28.1749 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O01 compound treatment 0.333 0.0149 1.2 0.34 0.0133 1.2 1.7008 1.0 2076136 Maybridge3_001717 N/C(=N\O)/Cc1nc2ccccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O02 compound treatment 0.338 0.0199 1.61 0.35 0.0233 2.11 2.6273 0.9909 1427339 Maybridge3_001718 Cc1csc2c(ncnc12)N3CCN(CC3)C(=O)c4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O03 compound treatment 0.331 0.0129 1.04 0.338 0.0113 1.02 1.4585 1.0 2076137 Maybridge3_001719 CCOC(=O)CC(=O)c1sc(SC)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O04 compound treatment 0.363 0.0449 3.62 0.372 0.0452 4.11 5.4629 0.998 1160544 Maybridge3_001720 COC(=O)C1=C(N)CC(S1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O05 compound treatment 0.328 0.00993 0.8 0.335 0.00825 0.75 1.0951 0.9995 1383651 Maybridge3_001721 CCOC(=O)CC(=O)Nc1ccn[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O06 compound treatment 0.332 0.0139 1.12 0.338 0.0113 1.02 1.5155 0.9989 2076138 Maybridge3_001722 C=CCNc1ncnc2sccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O07 compound treatment 0.334 0.0159 1.28 0.341 0.0143 1.29 1.8219 1.0 2076139 Maybridge3_001723 CCOC(=O)c1sc2ncccc2c1NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O08 compound treatment 0.329 0.0109 0.88 0.335 0.00825 0.75 1.1521 0.9968 1694803 Maybridge3_001724 O=S(=O)(N1CCN(CC1)c2ncnc3sccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O09 compound treatment 0.227 -0.0911 -7.33 0.243 -0.0838 -7.6 -10.5609 -0.9998 2076140 Maybridge3_001725 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)Sc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O10 compound treatment 0.331 0.0129 1.04 0.342 0.0153 1.38 1.7153 0.9902 2076141 Maybridge3_001726 Nc1ncc(C(=O)OCc2ccc(Cl)cc2)c(n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O11 compound treatment 0.345 0.0269 2.17 0.349 0.0222 2.02 2.9617 0.9994 2076142 Maybridge3_001727 FC(F)(F)c1c(cnn1c2ccc(Cl)cc2)C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O12 compound treatment 0.337 0.0189 1.52 0.34 0.0133 1.2 1.9285 0.9931 2076143 Maybridge3_001728 CCOC(=O)c1cc(=O)c2ccccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O13 compound treatment 0.323 0.00493 0.4 0.332 0.00525 0.48 0.6179 0.9959 2076144 Maybridge3_001729 COC(=O)c1sccc1OC(=O)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O14 compound treatment 0.335 0.0169 1.36 0.345 0.0182 1.66 2.1356 0.9953 2076145 Maybridge3_001730 CC(C)(C)c1cc2nc[nH]c(=O)c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O15 compound treatment 0.331 0.0129 1.04 0.337 0.0103 0.93 1.3943 0.9984 2076146 Maybridge3_001731 FC(F)(F)c1nc(ncc1C(=O)OCC2CC2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O16 compound treatment 0.345 0.0269 2.17 0.352 0.0253 2.29 3.1543 0.9996 1524766 Maybridge3_001732 COc1cc2ncnc(N3CC(C)OC(C)C3)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O17 compound treatment 0.336 0.0179 1.44 0.342 0.0153 1.38 2.0 0.9998 1276781 Maybridge3_001733 Cc1csc2ncnc(N3CCCCC3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O18 compound treatment 0.344 0.0259 2.09 0.351 0.0243 2.2 3.0332 0.9997 1122358 Maybridge3_001734 CCOC(=O)c1c(sc2CCCCc12)N3C(=O)CCC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O19 compound treatment 0.333 0.0149 1.2 0.347 0.0203 1.84 2.1501 0.9788 2076147 Maybridge3_001735 CCCCc1c(O)nc(O)nc1COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O20 compound treatment 0.331 0.0129 1.04 0.335 0.00825 0.75 1.266 0.9869 1624552 Maybridge3_001736 Cn1nccc1NS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O21 compound treatment 0.335 0.0169 1.36 0.341 0.0143 1.29 1.8788 0.9997 2076148 Maybridge3_001737 CCOc1ccsc1C(=O)Nc2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O22 compound treatment 0.339 0.0209 1.69 0.343 0.0163 1.48 2.235 0.9978 2076149 Maybridge3_001738 Cn1ncc2c(Sc3ccc(Cl)cc3)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O23 mock treatment 0.323 0.00493 0.4 0.332 0.00525 0.48 0.6179 0.9959 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 O24 positive control 0.09 -0.228 -18.37 0.091 -0.236 -21.4 -28.1179 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P01 compound treatment 0.331 0.0129 1.04 0.338 0.0113 1.02 1.4585 1.0 1201331 Maybridge3_001739 Cn1ncc2c(ncnc12)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P02 compound treatment 0.33 0.0119 0.96 0.338 0.0113 1.02 1.4016 0.9995 1397158 Maybridge3_001740 Fc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3coc4ccccc4c3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P03 compound treatment 0.34 0.0219 1.77 0.349 0.0222 2.02 2.677 0.9978 1182615 Maybridge3_001741 CC(C)(C)c1cc2ncnc(N3CCSCC3)c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P04 compound treatment 0.33 0.0119 0.96 0.337 0.0103 0.93 1.3374 0.9999 1476206 Maybridge3_001742 OC1(CCN(CC1)S(=O)(=O)c2cccc(Cl)c2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P05 compound treatment 0.337 0.0189 1.52 0.344 0.0173 1.57 2.1853 0.9999 1165694 Maybridge3_001743 COC(=O)c1sc(cc1NC(=O)c2ccco2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P06 compound treatment 0.327 0.00893 0.72 0.334 0.00725 0.66 0.974 0.999 1164946 Maybridge3_001744 OC(=O)C1CCC1C(=O)Nc2nc(cs2)c3ccc(Cl)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P07 compound treatment 0.324 0.00593 0.48 0.332 0.00525 0.48 0.6748 1.0 2076150 Maybridge3_001745 Clc1ccc(Cl)c(Sc2ncnc3ccsc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P08 compound treatment 0.353 0.0349 2.81 0.358 0.0313 2.84 3.9949 1.0 1230202 Maybridge3_001746 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2nn(C)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P09 compound treatment 0.331 0.0129 1.04 0.336 0.00925 0.84 1.3301 0.9943 2076151 Maybridge3_001747 FC(F)(F)c1ccn(n1)C(=O)Nc2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P10 compound treatment 0.334 0.0159 1.28 0.339 0.0123 1.11 1.6935 0.9975 2076152 Maybridge3_001748 COC(=O)c1scc(C)c1NC(=O)C2=Cc3cc(Cl)ccc3OC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P11 compound treatment 0.325 0.00693 0.56 0.331 0.00425 0.39 0.6676 0.9837 2076153 Maybridge3_001749 FC(F)(F)c1ccnc(NCCNc2ncccc2C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P12 compound treatment 0.324 0.00593 0.48 0.329 0.00225 0.2 0.4823 0.9281 2076154 Maybridge3_001750 FC(F)(F)Oc1ccc(cc1)C(=O)c2ncc[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P13 compound treatment 0.328 0.00993 0.8 0.332 0.00525 0.48 0.9026 0.9694 2076155 Maybridge3_001751 OC(=O)/C=C/C(=O)Nc1ccccc1Sc2nccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P14 compound treatment 0.333 0.0149 1.2 0.343 0.0163 1.48 1.8933 0.9949 2076156 Maybridge3_001752 FC(F)(F)c1ccc(cc1)c2noc(CNC(=O)C3CCCCC3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P15 compound treatment 0.338 0.0199 1.61 0.341 0.0143 1.29 2.0497 0.9943 1518767 Maybridge3_001753 CCS(=O)(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P16 compound treatment 0.32 0.00193 0.16 0.327 2.5E-4 0.02 0.1261 0.8017 1412363 Maybridge3_001754 OC(CNC1Cc2ccccc2C1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P17 compound treatment 0.323 0.00493 0.4 0.331 0.00425 0.39 0.5537 0.9999 1517339 Maybridge3_001755 O=c1[nH]cnc2scc(c3cccs3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P18 compound treatment 0.355 0.0369 2.97 0.357 0.0302 2.75 4.0446 0.9992 1228556 Maybridge3_001756 CC(C)(C)C(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P19 compound treatment 0.316 -0.00207 -0.17 0.321 -0.00575 -0.52 -0.4867 -0.8885 2076157 Maybridge3_001757 Clc1ccc(cc1)C2Nc3ccccc3-n4cccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P20 compound treatment 0.333 0.0149 1.2 0.34 0.0133 1.2 1.7008 1.0 1490734 Maybridge3_001758 OC(CN1CCN(CC1)C(c2ccccc2)c3ccccc3)Oc4ccc(Cl)c(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P21 compound treatment 0.339 0.0209 1.69 0.353 0.0262 2.38 2.8768 0.9856 2076158 Maybridge3_001759 Clc1ccc(s1)c2csc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P22 compound treatment 0.327 0.00893 0.72 0.335 0.00825 0.75 1.0382 0.9998 1486095 Maybridge3_001760 Cn1nc(NC(=O)CC(C)(C)CC(=O)O)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P23 mock treatment 0.318 -6.67E-5 -0.01 0.326 -7.5E-4 -0.07 -0.0519 -0.7605 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1435 P24 positive control 0.092 -0.226 -18.2 0.092 -0.235 -21.31 -27.9399 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A01 compound treatment 0.304 -0.0144 -1.16 0.298 -0.0143 -1.29 -1.7367 -0.9986 2076159 Maybridge3_001761 COc1ccc2[nH]c(cc2c1)C(=O)N3CCCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A02 compound treatment 0.304 -0.0144 -1.16 0.315 0.00275 0.25 -0.6456 -0.5429 1289168 Maybridge3_001762 CC(=O)Nc1nc2ccccc2c(=O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A03 compound treatment 0.308 -0.0104 -0.84 0.302 -0.0103 -0.93 -1.2522 -0.9987 1144978 Maybridge3_001763 COC(=O)Cc1nc(NS(=O)(=O)c2cccc(C)c2)sc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A04 compound treatment 0.314 -0.00444 -0.36 0.307 -0.00525 -0.48 -0.5896 -0.9899 2076160 Maybridge3_001764 NC(=O)c1ccc(cc1)c2ccnc(n2)c3ccc(Br)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A05 compound treatment 0.315 -0.00344 -0.28 0.312 -2.5E-4 -0.02 -0.2118 -0.7625 2076161 Maybridge3_001765 OC(COc1ccccc1)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A06 compound treatment 0.306 -0.0124 -1.0 0.301 -0.0113 -1.02 -1.4303 -1.0 1121453 Maybridge3_001766 OC(=O)CSCC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A07 compound treatment 0.308 -0.0104 -0.84 0.297 -0.0153 -1.38 -1.5731 -0.9714 2076162 Maybridge3_001767 Cc1ccc(Sc2ncccc2c3nnc(o3)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A08 compound treatment 0.303 -0.0154 -1.24 0.295 -0.0173 -1.57 -1.9862 -0.9935 1652052 Maybridge3_001768 Cn1c(ccc1S(=O)(=O)N2CCCCCC2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A09 compound treatment 0.298 -0.0204 -1.65 0.292 -0.0203 -1.84 -2.4635 -0.9985 2076163 Maybridge3_001769 COc1ccc2[nH]c(cc2c1)C(=O)NCCCn3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A10 compound treatment 0.304 -0.0144 -1.16 0.295 -0.0173 -1.57 -1.9293 -0.9893 1285449 Maybridge3_001770 O=C(CSc1nc(ns1)c2ccccc2)N3CCN(CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A11 compound treatment 0.31 -0.00844 -0.68 0.301 -0.0113 -1.02 -1.2025 -0.9804 1203346 Maybridge3_001771 COc1ccc2[nH]c(cc2c1)C(=O)N3CCCN(CC3)C(=O)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A12 compound treatment 0.329 0.0106 0.85 0.32 0.00775 0.7 1.0989 0.9956 1320215 Maybridge3_001772 CC(C)(CC(=O)O)CC(=O)N1CCCN(CC1)c2nc3ccc(Cl)cc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A13 compound treatment 0.305 -0.0134 -1.08 0.305 -0.00725 -0.66 -1.2305 -0.9716 1669794 Maybridge3_001773 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A14 compound treatment 0.298 -0.0204 -1.65 0.299 -0.0133 -1.2 -2.0142 -0.9881 1356787 Maybridge3_001774 Cc1nc(cs1)C(=O)NC2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A15 compound treatment 0.313 -0.00544 -0.44 0.313 7.5E-4 0.07 -0.2615 -0.5901 1151767 Maybridge3_001775 Clc1ccc2nc(sc2c1)N3CCN(CC3)S(=O)(=O)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A16 compound treatment 0.309 -0.00944 -0.76 0.308 -0.00425 -0.39 -0.8102 -0.9506 2076164 Maybridge3_001776 Cc1cc(ccc1NC(=O)CC(C)(C)CC(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A17 compound treatment 0.31 -0.00844 -0.68 0.31 -0.00225 -0.2 -0.6249 -0.8807 2076165 Maybridge3_001777 OC(CN1CCN(CC1)c2ccc(cn2)C(F)(F)F)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A18 compound treatment 0.307 -0.0114 -0.92 0.306 -0.00625 -0.57 -1.0524 -0.9729 2076166 Maybridge3_001778 CCOC(=O)c1cnc(SCC(=O)c2cc(Cl)c(Cl)s2)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A19 compound treatment 0.313 -0.00544 -0.44 0.312 -2.5E-4 -0.02 -0.3257 -0.7428 1395572 Maybridge3_001779 Clc1cc(Cl)cc(c1)S(=O)(=O)N2CCN(CC2)S(=O)(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A20 compound treatment 0.307 -0.0114 -0.92 0.308 -0.00425 -0.39 -0.924 -0.9254 1238504 Maybridge3_001780 OC(=O)c1nccnc1C(=O)N2CCc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A21 compound treatment 0.304 -0.0144 -1.16 0.308 -0.00425 -0.39 -1.0949 -0.8938 1149541 Maybridge3_001781 Cc1ncc(CN2CCSCC2)c(CO)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A22 compound treatment 0.302 -0.0164 -1.32 0.307 -0.00525 -0.48 -1.2729 -0.9048 1510125 Maybridge3_001782 COC(=O)c1sccc1NS(=O)(=O)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A23 mock treatment 0.301 -0.0174 -1.4 0.302 -0.0103 -0.93 -1.6508 -0.98 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 A24 positive control 0.082 -0.236 -19.04 0.086 -0.226 -20.54 -27.9848 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B01 compound treatment 0.331 0.0126 1.01 0.334 0.0217 1.97 2.1113 0.9518 1709094 Maybridge3_001783 Cc1cn(CCC(=O)NC2Cc3ccccc3C2)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B02 compound treatment 0.339 0.0206 1.66 0.34 0.0278 2.52 2.952 0.9793 1425253 Maybridge3_001784 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3c[nH]c(C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B03 compound treatment 0.338 0.0196 1.58 0.333 0.0208 1.88 2.4457 0.9961 1224476 Maybridge3_001785 O=C(NC1CCN(CC1)C(=O)c2cccnc2Oc3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B04 compound treatment 0.33 0.0116 0.93 0.329 0.0168 1.52 1.7335 0.9723 1610684 Maybridge3_001786 Cc1nnsc1C(=O)NCc2cc(F)cc3COCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B05 compound treatment 0.338 0.0196 1.58 0.327 0.0147 1.34 2.0606 0.9967 1445089 Maybridge3_001787 Cc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B06 compound treatment 0.326 0.00756 0.61 0.324 0.0118 1.07 1.1848 0.9647 2076167 Maybridge3_001788 OC(=O)COCC(=O)Nc1ccccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B07 compound treatment 0.32 0.00156 0.13 0.319 0.00675 0.61 0.5222 0.8349 2076168 Maybridge3_001789 Clc1ccc(Oc2nc(ns2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B08 compound treatment 0.328 0.00956 0.77 0.324 0.0118 1.07 1.2987 0.9872 2076169 Maybridge3_001790 Cn1c(Sc2nc3ccc(Cl)cc3s2)nnc1c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B09 compound treatment 0.347 0.0286 2.3 0.343 0.0308 2.79 3.6001 0.9954 1569106 Maybridge3_001791 Cc1c(cnn1c2ccc(F)cc2)C(=O)N3CCCc4cc(C)ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B10 compound treatment 0.326 0.00756 0.61 0.325 0.0127 1.16 1.249 0.955 1355709 Maybridge3_001792 CCCc1c(cnn1c2ccccc2)C(=O)Nc3cc(C)on3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B11 compound treatment 0.326 0.00756 0.61 0.328 0.0158 1.43 1.4415 0.9277 1422958 Maybridge3_001793 Cn1cc(Br)c(n1)c2cccc(NC(=O)CCC(=O)O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B12 compound treatment 0.336 0.0176 1.41 0.337 0.0248 2.25 2.5886 0.9751 1357606 Maybridge3_001794 COC(=O)C1=C(C)NC2=C(C1c3cn[nH]c3)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B13 compound treatment 0.33 0.0116 0.93 0.322 0.00975 0.89 1.2842 0.9997 1462525 Maybridge3_001795 O=S(=O)(NC1CCS(=O)(=O)C1)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B14 compound treatment 0.333 0.0146 1.17 0.319 0.00675 0.61 1.2625 0.9542 2076170 Maybridge3_001796 Cc1nc(ccc1C(=O)NCc2ccc3OCOc3c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B15 compound treatment 0.329 0.0106 0.85 0.325 0.0127 1.16 1.4198 0.9885 1690637 Maybridge3_001797 OC(=O)CSCC(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B16 compound treatment 0.352 0.0336 2.7 0.347 0.0347 3.15 4.1415 0.997 1619255 Maybridge3_001798 O=C(Oc1ccccc1N2CCOCC2)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B17 compound treatment 0.332 0.0136 1.09 0.323 0.0107 0.98 1.4622 0.9984 2076171 Maybridge3_001799 Cc1noc(C)c1C(=O)Nc2ccc3COC(=O)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B18 compound treatment 0.359 0.0406 3.27 0.361 0.0488 4.43 5.4387 0.9888 1136648 Maybridge3_001800 CCCc1c(cnn1c2ccccc2)C(=O)N3CCN(CC3)c4ccccc4OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B19 compound treatment 0.331 0.0126 1.01 0.328 0.0158 1.43 1.7262 0.9857 2076172 Maybridge3_001801 CCCc1cc(=O)n2nc(c(c3ccccc3)c2[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B20 compound treatment 0.343 0.0246 1.98 0.346 0.0337 3.06 3.5649 0.9776 2076173 Maybridge3_001802 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(o3)c4ccc(OC(F)(F)F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B21 compound treatment 0.356 0.0376 3.02 0.358 0.0457 4.15 5.0753 0.9879 1174886 Maybridge3_001803 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)COCC(=O)O)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B22 compound treatment 0.323 0.00456 0.37 0.319 0.00675 0.61 0.693 0.9701 1411197 Maybridge3_001804 Clc1cc(c(Cl)s1)S(=O)(=O)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B23 mock treatment 0.324 0.00556 0.45 0.316 0.00375 0.34 0.5574 0.9908 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 B24 positive control 0.082 -0.236 -19.04 0.082 -0.23 -20.9 -28.2416 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C01 compound treatment 0.333 0.0146 1.17 0.332 0.0198 1.79 2.0969 0.9788 2076174 Maybridge3_001805 COc1ccc2[nH]c(cc2c1)C(=O)N(Cc3ccccn3)Cc4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C02 compound treatment 0.326 0.00756 0.61 0.33 0.0177 1.61 1.5699 0.9114 1138190 Maybridge3_001806 COc1cc2nc(NC(=O)C)sc(=O)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C03 compound treatment 0.315 -0.00344 -0.28 0.31 -0.00225 -0.2 -0.3402 -0.9888 1308981 Maybridge3_001807 Cc1cc(OCC(=O)Nc2ccc3OCOc3c2)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C04 compound treatment 0.341 0.0226 1.82 0.345 0.0327 2.97 3.3868 0.9721 1454586 Maybridge3_001808 COc1ccc(cc1)c2ccnc(n2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C05 compound treatment 0.317 -0.00144 -0.12 0.32 0.00775 0.7 0.4156 0.5829 2076175 Maybridge3_001809 Oc1ccc(cc1)n2nnnc2SC3Cc4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C06 compound treatment 0.321 0.00256 0.21 0.327 0.0147 1.34 1.0926 0.8066 1414963 Maybridge3_001810 CC(C)(CC(=O)O)CC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C07 compound treatment 0.316 -0.00244 -0.2 0.314 0.00175 0.16 -0.0265 -0.1048 2076176 Maybridge3_001811 COC(=O)c1sccc1NS(=O)(=O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C08 compound treatment 0.328 0.00956 0.77 0.325 0.0127 1.16 1.3629 0.9804 1566340 Maybridge3_001812 OC1(CCN(CC1)C(=O)c2cc3ccccc3s2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C09 compound treatment 0.316 -0.00244 -0.2 0.304 -0.00825 -0.75 -0.6683 -0.8633 1181008 Maybridge3_001813 COc1ccc2[nH]c(cc2c1)C(=O)NC3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C10 compound treatment 0.32 0.00156 0.13 0.32 0.00775 0.7 0.5864 0.8206 1144529 Maybridge3_001814 O=S(=O)(N1CCN(CCc2ccccc2)CC1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C11 compound treatment 0.325 0.00656 0.53 0.31 -0.00225 -0.2 0.2293 0.4047 1638350 Maybridge3_001815 NC(=O)C1CCN(CC(O)COc2ccc(Br)cc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C12 compound treatment 0.307 -0.0114 -0.92 0.303 -0.00925 -0.84 -1.245 -0.9989 1402740 Maybridge3_001816 CSc1cccc(NC(=O)CSCc2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C13 compound treatment 0.343 0.0246 1.98 0.347 0.0347 3.15 3.629 0.9747 1301094 Maybridge3_001817 COc1ccccc1N2CCN(CC2)C(=O)C(C)Oc3ccnc4c(C)ccc(C)c34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C14 compound treatment 0.326 0.00756 0.61 0.325 0.0127 1.16 1.249 0.955 2076177 Maybridge3_001818 Cc1cc(C)c(c(C)c1)n2nnnc2SC3Cc4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C15 compound treatment 0.331 0.0126 1.01 0.319 0.00675 0.61 1.1486 0.9711 1406744 Maybridge3_001819 O=C(Nc1nc2ccsc2c(=O)s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C16 compound treatment 0.333 0.0146 1.17 0.324 0.0118 1.07 1.5834 0.9989 1243460 Maybridge3_001820 Cc1cc(ccc1NC(=O)COCC(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C17 compound treatment 0.34 0.0216 1.74 0.328 0.0158 1.43 2.2387 0.9953 2076178 Maybridge3_001821 OC(CN1CCN(CC1)c2ccc(cn2)C(F)(F)F)c3cc(no3)c4cc(Cl)cc(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C18 compound treatment 0.348 0.0296 2.38 0.334 0.0217 1.97 3.0793 0.9957 2076179 Maybridge3_001822 CCOC(=O)c1cnc(SCc2ccc(Cl)cc2)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C19 compound treatment 0.331 0.0126 1.01 0.322 0.00975 0.89 1.3411 0.9978 2076180 Maybridge3_001823 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C20 compound treatment 0.325 0.00656 0.53 0.325 0.0127 1.16 1.192 0.9369 2076181 Maybridge3_001824 O=C(c1cccs1)c2ncc[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C21 compound treatment 0.33 0.0116 0.93 0.352 0.0398 3.61 3.2097 0.8614 2076182 Maybridge3_001825 c1csc(c1)c2ccnc3cc(nn23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C22 compound treatment 0.329 0.0106 0.85 0.327 0.0147 1.34 1.5482 0.976 1255364 Maybridge3_001826 Cc1ccnc(NS(=O)(=O)c2ccc3OCCc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C23 mock treatment 0.317 -0.00144 -0.12 0.31 -0.00225 -0.2 -0.2263 -0.9638 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 C24 positive control 0.087 -0.231 -18.64 0.084 -0.228 -20.72 -27.8285 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D01 compound treatment 0.341 0.0226 1.82 0.333 0.0208 1.88 2.6166 0.9998 2076183 Maybridge3_001827 COC(=O)Cc1nc(sc1C)c2ccc(s2)c3ccon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D02 compound treatment 0.335 0.0166 1.33 0.335 0.0227 2.07 2.4033 0.9776 1328413 Maybridge3_001828 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3c[nH]cn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D03 compound treatment 0.35 0.0316 2.54 0.343 0.0308 2.79 3.7709 0.9989 1623316 Maybridge3_001829 Cc1cnc(cn1)C(=O)NCc2c(Cl)cccc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D04 compound treatment 0.332 0.0136 1.09 0.32 0.00775 0.7 1.2697 0.9774 1437927 Maybridge3_001830 Cc1noc(C)c1C(=O)NCc2cc(F)cc3COCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D05 compound treatment 0.342 0.0236 1.9 0.343 0.0308 2.79 3.3154 0.9823 1132631 Maybridge3_001831 Clc1ccc(c(Cl)c1)S(=O)(=O)CCN2CCN(CC2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D06 compound treatment 0.325 0.00656 0.53 0.325 0.0127 1.16 1.192 0.9369 1637108 Maybridge3_001832 CC(C)(C)c1ccc(cc1)c2nc(=O)c3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D07 compound treatment 0.331 0.0126 1.01 0.316 0.00375 0.34 0.956 0.8957 1531733 Maybridge3_001833 COc1ccc(Oc2nc(ns2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D08 compound treatment 0.327 0.00856 0.69 0.323 0.0107 0.98 1.1775 0.9855 1276365 Maybridge3_001834 Cn1nc(c(NC(=O)c2cccs2)c1C(C)(C)C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D09 compound treatment 0.329 0.0106 0.85 0.327 0.0147 1.34 1.5482 0.976 2076184 Maybridge3_001835 Cc1c(cnn1c2ccc(F)cc2)C(=O)Nc3ccc(N4CCOCC4)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D10 compound treatment 0.348 0.0296 2.38 0.345 0.0327 2.97 3.7854 0.9939 2076185 Maybridge3_001836 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc(cc3)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D11 compound treatment 0.336 0.0176 1.41 0.329 0.0168 1.52 2.0751 0.9993 2076186 Maybridge3_001837 Cn1cc(Br)c(n1)c2cccc(NC(=O)/C=C/C(=O)O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D12 compound treatment 0.351 0.0326 2.62 0.341 0.0288 2.61 3.6995 1.0 1400578 Maybridge3_001838 COC(=O)C1=C(C)NC2=C(C1c3ccc(s3)c4cccs4)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D13 compound treatment 0.33 0.0116 0.93 0.323 0.0107 0.98 1.3484 0.9997 2076187 Maybridge3_001839 Cc1onc(c1C(=O)NC2CCS(=O)(=O)C2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D14 compound treatment 0.335 0.0166 1.33 0.325 0.0127 1.16 1.7614 0.9975 1283528 Maybridge3_001840 CSc1nsc(SC)c1C(=O)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D15 compound treatment 0.329 0.0106 0.85 0.321 0.00875 0.79 1.1631 0.9994 2076188 Maybridge3_001841 OC(=O)/C=C/C(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D16 compound treatment 0.331 0.0126 1.01 0.32 0.00775 0.7 1.2128 0.9842 1521021 Maybridge3_001842 NC(=O)C1CCN(Cc2nc(no2)c3cccs3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D17 compound treatment 0.329 0.0106 0.85 0.334 0.0217 1.97 1.9975 0.9292 2076189 Maybridge3_001843 Cc1nnsc1C(=O)Nc2ccc3COC(=O)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D18 compound treatment 0.331 0.0126 1.01 0.329 0.0168 1.52 1.7904 0.9804 1678627 Maybridge3_001844 CCCc1c(cnn1c2ccccc2)C(=O)NCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D19 compound treatment 0.329 0.0106 0.85 0.326 0.0138 1.25 1.484 0.9825 2076190 Maybridge3_001845 Cc1cc(=O)n2nc(c(c3ccccc3)c2[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D20 compound treatment 0.332 0.0136 1.09 0.326 0.0138 1.25 1.6548 0.9978 1208568 Maybridge3_001846 COc1cccc2n(C)nc(NS(=O)(=O)c3cc(Cl)sc3Cl)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D21 compound treatment 0.354 0.0356 2.86 0.359 0.0468 4.24 5.0256 0.9817 1778654 Maybridge3_001847 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)CCCC(=O)O)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D22 compound treatment 0.333 0.0146 1.17 0.328 0.0158 1.43 1.8401 0.9952 1610475 Maybridge3_001848 OCCCC(=O)Nc1ccc2OCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D23 mock treatment 0.317 -0.00144 -0.12 0.317 0.00475 0.43 0.223 0.4996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 D24 positive control 0.086 -0.232 -18.72 0.085 -0.227 -20.63 -27.8212 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E01 compound treatment 0.331 0.0126 1.01 0.326 0.0138 1.25 1.5979 0.9946 1375780 Maybridge3_001849 COc1ccc(COCC(O)CN2CCC(CC2)C(=O)N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E02 compound treatment 0.329 0.0106 0.85 0.326 0.0138 1.25 1.484 0.9825 1472811 Maybridge3_001850 CC(=O)Nc1nc2c(Br)cc(Br)cc2c(=O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E03 compound treatment 0.331 0.0126 1.01 0.323 0.0107 0.98 1.4053 0.9998 1234629 Maybridge3_001851 CC1=C(C)CC(C(C1)C(=O)O)C(=O)NCc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E04 compound treatment 0.319 5.63E-4 0.05 0.309 -0.00325 -0.3 -0.1766 -0.5916 2076191 Maybridge3_001852 COc1ccc(cc1)c2ccnc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E05 compound treatment 0.32 0.00156 0.13 0.305 -0.00725 -0.66 -0.3764 -0.5617 1267360 Maybridge3_001853 OC(CNCc1ccc2OCOc2c1)CSc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E06 compound treatment 0.341 0.0226 1.82 0.331 0.0187 1.7 2.4882 0.9995 1357638 Maybridge3_001854 CC1=C(C)CC(C(C1)C(=O)O)C(=O)N2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E07 compound treatment 0.329 0.0106 0.85 0.323 0.0107 0.98 1.2914 0.9977 2076192 Maybridge3_001855 Cc1csc2nc(NC(=O)c3ccccc3)sc(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E08 compound treatment 0.333 0.0146 1.17 0.329 0.0168 1.52 1.9043 0.9918 2076193 Maybridge3_001856 Fc1ccc(cc1)C(=O)Nc2cccnc2Sc3nc4cccnc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E09 compound treatment 0.343 0.0246 1.98 0.346 0.0337 3.06 3.5649 0.9776 1676542 Maybridge3_001857 CCOc1ccccc1N2CCN(CC2)C(=O)c3cc4cc(OC)ccc4[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E10 compound treatment 0.32 0.00156 0.13 0.312 -2.5E-4 -0.02 0.0729 0.5704 1635945 Maybridge3_001858 Cc1ccc(cc1C)C(=O)NC2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E11 compound treatment 0.319 5.63E-4 0.05 0.32 0.00775 0.7 0.5295 0.7511 1608144 Maybridge3_001859 NC(=O)C1CCN(CC(O)Cc2ccc3OCOc3c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E12 compound treatment 0.329 0.0106 0.85 0.315 0.00275 0.25 0.7779 0.8776 1421979 Maybridge3_001860 Cc1nn(C)c2ncc(C(=O)O)c(Sc3ccc(C)cc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E13 compound treatment 0.34 0.0216 1.74 0.324 0.0118 1.07 1.982 0.9726 2076194 Maybridge3_001861 FC(F)(F)c1cc(OCC(=O)Nc2ccc3OCOc3c2)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E14 compound treatment 0.308 -0.0104 -0.84 0.305 -0.00725 -0.66 -1.0597 -0.9927 1573079 Maybridge3_001862 O=C(Nc1cccc(c1)c2cnco2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E15 compound treatment 0.358 0.0396 3.19 0.348 0.0357 3.25 4.5473 1.0 1196147 Maybridge3_001863 Cc1csc2c(=O)sc(NC(=O)c3ccco3)nc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E16 compound treatment 0.327 0.00856 0.69 0.326 0.0138 1.25 1.3701 0.9609 1326795 Maybridge3_001864 OC(=O)c1cccnc1SCC(=O)c2cc3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E17 compound treatment 0.325 0.00656 0.53 0.319 0.00675 0.61 0.8069 0.9973 1713724 Maybridge3_001865 Cc1cc(C)c(C#N)c(OCC(=O)Nc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E18 compound treatment 0.319 5.63E-4 0.05 0.31 -0.00225 -0.2 -0.1124 -0.5372 2076195 Maybridge3_001866 CCOC(=O)c1cnc(SCc2cccc(c2)C(F)(F)F)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E19 compound treatment 0.345 0.0266 2.14 0.346 0.0337 3.06 3.6787 0.9846 2076196 Maybridge3_001867 COC(=O)c1sc(cc1NC(=O)CSCC(=O)O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E20 compound treatment 0.33 0.0116 0.93 0.332 0.0198 1.79 1.926 0.9534 1627635 Maybridge3_001868 Cn1cnc(c1)S(=O)(=O)N(Cc2cccs2)Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E21 compound treatment 0.322 0.00356 0.29 0.322 0.00975 0.89 0.8287 0.8907 1732230 Maybridge3_001869 COC(=O)c1ccc(n1C)S(=O)(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E22 compound treatment 0.322 0.00356 0.29 0.32 0.00775 0.7 0.7003 0.9218 2076197 Maybridge3_001870 OC(=O)c1ccccc1SCCS(=O)(=O)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E23 mock treatment 0.314 -0.00444 -0.36 0.309 -0.00325 -0.3 -0.4613 -0.9955 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 E24 positive control 0.087 -0.231 -18.64 0.086 -0.226 -20.54 -27.7001 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F01 compound treatment 0.335 0.0166 1.33 0.33 0.0177 1.61 2.0824 0.9956 1703071 Maybridge3_001871 O=C(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F02 compound treatment 0.332 0.0136 1.09 0.324 0.0118 1.07 1.5264 0.9999 2076198 Maybridge3_001872 Nc1nc(cc(n1)C(F)(F)F)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F03 compound treatment 0.337 0.0186 1.49 0.332 0.0198 1.79 2.3246 0.9959 2076199 Maybridge3_001873 Cc1cnc(cn1)C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F04 compound treatment 0.331 0.0126 1.01 0.326 0.0138 1.25 1.5979 0.9946 2076200 Maybridge3_001874 COC(=O)c1cc(c(s1)C(F)(F)F)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F05 compound treatment 0.344 0.0256 2.06 0.328 0.0158 1.43 2.4665 0.9841 2076201 Maybridge3_001875 CC(C)(C)C(=O)CSc1nnc(O)n1c2ccccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F06 compound treatment 0.343 0.0246 1.98 0.333 0.0208 1.88 2.7304 0.9997 1307137 Maybridge3_001876 COc1cc(cc(Br)c1O)c2nc(=O)c3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F07 compound treatment 0.323 0.00456 0.37 0.316 0.00375 0.34 0.5005 0.9993 2076202 Maybridge3_001877 S(c1nc(ns1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F08 compound treatment 0.335 0.0166 1.33 0.337 0.0248 2.25 2.5317 0.969 1319754 Maybridge3_001878 Cn1nc(c(NC(=O)c2cccnc2)c1C(C)(C)C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F09 compound treatment 0.347 0.0286 2.3 0.349 0.0367 3.34 3.9852 0.9835 1323393 Maybridge3_001879 COC(=O)C1=C(C)NC2=C(C1c3c[nH]c4ccccc34)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F10 compound treatment 0.327 0.00856 0.69 0.317 0.00475 0.43 0.7924 0.9744 1473096 Maybridge3_001880 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F11 compound treatment 0.333 0.0146 1.17 0.326 0.0138 1.25 1.7117 0.9995 1222443 Maybridge3_001881 Cn1cc(Br)c(n1)c2cccc(NC(=O)CC(C)(C)CC(=O)O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F12 compound treatment 0.374 0.0556 4.47 0.353 0.0408 3.7 5.7793 0.9955 1194425 Maybridge3_001882 COC(=O)C1=C(C)NC2=C(C1c3ccc4CCOc4c3)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F13 compound treatment 0.337 0.0186 1.49 0.327 0.0147 1.34 2.0037 0.9985 2076203 Maybridge3_001883 Cc1ccc(cc1)S(=O)(=O)CCSc2nnc(c3ccco3)n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F14 compound treatment 0.328 0.00956 0.77 0.327 0.0147 1.34 1.4912 0.9655 1622129 Maybridge3_001884 O=C(NCc1ccc2OCOc2c1)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F15 compound treatment 0.332 0.0136 1.09 0.333 0.0208 1.88 2.1041 0.9664 1352978 Maybridge3_001885 OC(=O)c1ccccc1C(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F16 compound treatment 0.333 0.0146 1.17 0.327 0.0147 1.34 1.7759 0.9978 1353591 Maybridge3_001886 C(N1CCOCC1)c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F17 compound treatment 0.333 0.0146 1.17 0.327 0.0147 1.34 1.7759 0.9978 1733397 Maybridge3_001887 O=C(Nc1ccc2COC(=O)c2c1)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F18 compound treatment 0.329 0.0106 0.85 0.339 0.0267 2.43 2.3184 0.9011 1688160 Maybridge3_001888 CCCc1c(cnn1c2ccccc2)C(=O)Nc3cc(on3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F19 compound treatment 0.327 0.00856 0.69 0.32 0.00775 0.7 0.985 0.9999 1407076 Maybridge3_001889 COC(=O)c1sccc1c2ccc(CN3CCN(CC3)c4ccccc4)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F20 compound treatment 0.306 -0.0124 -1.0 0.306 -0.00625 -0.57 -1.1094 -0.9638 2076204 Maybridge3_001890 OC(CNC1CCc2ccccc12)COc3ccc(cc3)c4csnn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F21 compound treatment 0.339 0.0206 1.66 0.339 0.0267 2.43 2.8878 0.9826 2076205 Maybridge3_001891 Cc1nc(cs1)c2ccc(NC(=O)c3ccc(nc3C)C(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F22 compound treatment 0.332 0.0136 1.09 0.327 0.0147 1.34 1.719 0.9949 2076206 Maybridge3_001892 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F23 mock treatment 0.32 0.00156 0.13 0.311 -0.00125 -0.11 0.0087 0.0516 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 F24 positive control 0.087 -0.231 -18.64 0.086 -0.226 -20.54 -27.7001 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G01 compound treatment 0.325 0.00656 0.53 0.313 7.5E-4 0.07 0.4218 0.7917 1398350 Maybridge3_001893 COc1ccc(COCC(O)CNC2Cc3ccccc3C2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G02 compound treatment 0.327 0.00856 0.69 0.321 0.00875 0.79 1.0492 0.9975 1214137 Maybridge3_001894 O=C(Nc1nc2ccsc2c(=O)s1)C3CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G03 compound treatment 0.334 0.0156 1.25 0.329 0.0168 1.52 1.9612 0.9954 1482663 Maybridge3_001895 CCn1nc(C)cc1C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G04 compound treatment 0.351 0.0326 2.62 0.34 0.0278 2.52 3.6353 0.9998 2076207 Maybridge3_001896 CN(C)c1ccc(cc1)n2nnnc2SCC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G05 compound treatment 0.297 -0.0214 -1.73 0.292 -0.0203 -1.84 -2.5204 -0.9995 1612539 Maybridge3_001897 OC(CSc1cccs1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G06 compound treatment 0.323 0.00456 0.37 0.312 -2.5E-4 -0.02 0.2437 0.6622 1207596 Maybridge3_001898 CCOC(=O)N1CCC2(CC1)NCCc3c2[nH]c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G07 compound treatment 0.347 0.0286 2.3 0.342 0.0297 2.7 3.5359 0.9968 1640320 Maybridge3_001899 COC(=O)c1sc(cc1NC(=O)CCC(=O)O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G08 compound treatment 0.328 0.00956 0.77 0.32 0.00775 0.7 1.0419 0.999 1134477 Maybridge3_001900 NC(=O)c1ccccc1OC2CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G09 compound treatment 0.312 -0.00644 -0.52 0.307 -0.00525 -0.48 -0.7035 -0.9991 2076208 Maybridge3_001901 COc1ccc2[nH]c(cc2c1)C(=O)NCCNc3cccc(n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G10 compound treatment 0.319 5.63E-4 0.05 0.313 7.5E-4 0.07 0.0802 0.9804 1149075 Maybridge3_001902 COc1cscc1C(=O)NC2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G11 compound treatment 0.351 0.0326 2.62 0.345 0.0327 2.97 3.9562 0.998 1309051 Maybridge3_001903 OC(COc1ccc(F)cc1)CN2CCN(CC2)c3nc4ccc(Cl)cc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G12 compound treatment 0.332 0.0136 1.09 0.322 0.00975 0.89 1.3981 0.9946 2076209 Maybridge3_001904 OC(=O)c1ccccc1C(=O)Nc2ccc(Br)c(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G13 compound treatment 0.353 0.0346 2.78 0.337 0.0248 2.25 3.5566 0.9944 2076210 Maybridge3_001905 Cc1cc(OCC(=O)Nc2ccc(OC(F)(F)F)cc2)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G14 compound treatment 0.335 0.0166 1.33 0.334 0.0217 1.97 2.3391 0.9818 2076211 Maybridge3_001906 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc(c2)c3cnco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G15 compound treatment 0.328 0.00956 0.77 0.326 0.0138 1.25 1.427 0.9731 1534087 Maybridge3_001907 O=C(Nc1nc2ccccc2c(=O)s1)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G16 compound treatment 0.321 0.00256 0.21 0.312 -2.5E-4 -0.02 0.1299 0.6256 2076212 Maybridge3_001908 Cc1ccc(c(C)c1)n2nnnc2SCC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G17 compound treatment 0.324 0.00556 0.45 0.316 0.00375 0.34 0.5574 0.9908 1388311 Maybridge3_001909 COc1cccc(c1)C2(O)CCSc3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G18 compound treatment 0.34 0.0216 1.74 0.328 0.0158 1.43 2.2387 0.9953 1201535 Maybridge3_001910 COC(=O)c1cnc(SCc2ccc(cc2)C(C)(C)C)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G19 compound treatment 0.322 0.00356 0.29 0.315 0.00275 0.25 0.3794 0.9976 1204218 Maybridge3_001911 Clc1ccc(cc1)C(=O)Nc2nc3ccccc3c(=O)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G20 compound treatment 0.337 0.0186 1.49 0.329 0.0168 1.52 2.1321 1.0 1610274 Maybridge3_001912 Cc1cn(nc1C(=O)Nc2nn(C)c3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G21 compound treatment 0.318 -4.37E-4 -0.04 0.316 0.00375 0.34 0.2158 0.6306 2076213 Maybridge3_001913 c1csc(c1)c2nc(cs2)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G22 compound treatment 0.325 0.00656 0.53 0.324 0.0118 1.07 1.1278 0.9475 2076214 Maybridge3_001914 COCc1cc(O)nc(SCCS(=O)(=O)c2ccc(C)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G23 mock treatment 0.316 -0.00244 -0.2 0.312 -2.5E-4 -0.02 -0.1548 -0.7836 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 G24 positive control 0.09 -0.228 -18.4 0.087 -0.225 -20.45 -27.4651 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H01 compound treatment 0.333 0.0146 1.17 0.324 0.0118 1.07 1.5834 0.9989 1495881 Maybridge3_001915 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)Nc3cccnc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H02 compound treatment 0.341 0.0226 1.82 0.341 0.0288 2.61 3.13 0.9843 2076215 Maybridge3_001916 Nc1nc(cc(n1)C(F)(F)F)c2ccc3CCCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H03 compound treatment 0.334 0.0156 1.25 0.324 0.0118 1.07 1.6403 0.9968 1145280 Maybridge3_001917 Cn1cnc(c1)S(=O)(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H04 compound treatment 0.334 0.0156 1.25 0.331 0.0187 1.7 2.0896 0.9887 1676811 Maybridge3_001918 Cc1nc(sc1C(=O)NC2CCS(=O)(=O)C2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H05 compound treatment 0.333 0.0146 1.17 0.327 0.0147 1.34 1.7759 0.9978 2076216 Maybridge3_001919 Oc1nnc(SCC(=O)c2ccc(F)cc2)n1c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H06 compound treatment 0.337 0.0186 1.49 0.326 0.0138 1.25 1.9395 0.996 1616667 Maybridge3_001920 OCCCC(=O)NCc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H07 compound treatment 0.326 0.00756 0.61 0.322 0.00975 0.89 1.0564 0.9834 2076217 Maybridge3_001921 Cc1cc(no1)C(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H08 compound treatment 0.321 0.00256 0.21 0.32 0.00775 0.7 0.6433 0.8775 1599781 Maybridge3_001922 Cc1snnc1C(=O)Nc2c(nn(C)c2C(C)(C)C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H09 compound treatment 0.328 0.00956 0.77 0.316 0.00375 0.34 0.7852 0.9326 1713212 Maybridge3_001923 Cc1c(cnn1c2ccc(F)cc2)C(=O)NC3Cc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H10 compound treatment 0.324 0.00556 0.45 0.325 0.0127 1.16 1.1351 0.9147 2076218 Maybridge3_001924 CCCc1c(cnn1c2ccccc2)C(=O)NCCCn3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H11 compound treatment 0.329 0.0106 0.85 0.324 0.0118 1.07 1.3556 0.9937 2076219 Maybridge3_001925 Nc1nc(SCc2cccc(c2)C(F)(F)F)ncc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H12 compound treatment 0.365 0.0466 3.75 0.36 0.0478 4.33 5.7161 0.9974 1391463 Maybridge3_001926 COC(=O)C1=C(C)NC2=C(C1c3ccc4OC(C)(C)CCc4c3)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H13 compound treatment 0.335 0.0166 1.33 0.312 -2.5E-4 -0.02 0.927 0.695 2076220 Maybridge3_001927 Cn1c(SCC(=O)c2cc(Cl)c(Cl)s2)nnc1c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H14 compound treatment 0.324 0.00556 0.45 0.323 0.0107 0.98 1.0067 0.9376 1262660 Maybridge3_001928 Cc1cc(NC(=O)CCCO)[nH]n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H15 compound treatment 0.311 -0.00744 -0.6 0.307 -0.00525 -0.48 -0.7605 -0.9936 1670881 Maybridge3_001929 C(OCc1ccc2OCCc2c1)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H16 compound treatment 0.327 0.00856 0.69 0.322 0.00975 0.89 1.1134 0.9924 1238598 Maybridge3_001930 O=C1N(Cc2ccccc2)S(=O)(=O)Nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H17 compound treatment 0.337 0.0186 1.49 0.328 0.0158 1.43 2.0679 0.9998 1669500 Maybridge3_001931 OCCCC(=O)NCc1ccc2OCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H18 compound treatment 0.349 0.0306 2.46 0.341 0.0288 2.61 3.5856 0.9996 2076221 Maybridge3_001932 CCCc1c(cnn1c2ccccc2)C(=O)N3CC(C)OC(C)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H19 compound treatment 0.351 0.0326 2.62 0.339 0.0267 2.43 3.5711 0.9993 2076222 Maybridge3_001933 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H20 compound treatment 0.33 0.0116 0.93 0.324 0.0118 1.07 1.4126 0.9977 1370216 Maybridge3_001934 OC(=O)CCC(=O)NCc1csc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H21 compound treatment 0.327 0.00856 0.69 0.327 0.0147 1.34 1.4343 0.9524 1416019 Maybridge3_001935 Cc1nc(cs1)c2ccc(NC(=O)COCC(=O)O)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H22 compound treatment 0.323 0.00456 0.37 0.327 0.0147 1.34 1.2065 0.869 1585644 Maybridge3_001936 Cc1ccsc1CNC(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H23 mock treatment 0.319 5.63E-4 0.05 0.315 0.00275 0.25 0.2085 0.822 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 H24 positive control 0.089 -0.229 -18.48 0.088 -0.224 -20.36 -27.4579 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I01 compound treatment 0.344 0.0256 2.06 0.34 0.0278 2.52 3.2367 0.995 2076223 Maybridge3_001937 COc1ccc(COCC(O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I02 compound treatment 0.331 0.0126 1.01 0.325 0.0127 1.16 1.5337 0.9978 1227256 Maybridge3_001938 Brc1cc(Br)c2nc(NC(=O)C3CCC3)sc(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I03 compound treatment 0.337 0.0186 1.49 0.333 0.0208 1.88 2.3888 0.9934 2076224 Maybridge3_001939 OC(=O)CSCc1nc(no1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I04 compound treatment 0.348 0.0296 2.38 0.339 0.0267 2.43 3.4003 1.0 2076225 Maybridge3_001940 Oc1ccc(cc1)n2nnnc2SCC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I05 compound treatment 0.331 0.0126 1.01 0.329 0.0168 1.52 1.7904 0.9804 1189762 Maybridge3_001941 Cc1ccc(OCC(O)CN2CCC(CC2)C(=O)N)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I06 compound treatment 0.342 0.0236 1.9 0.33 0.0177 1.61 2.481 0.9967 1189475 Maybridge3_001942 COc1ccc(cc1)C(=O)N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I07 compound treatment 0.251 -0.0674 -5.43 0.233 -0.0793 -7.19 -8.9266 -0.9904 2076226 Maybridge3_001943 COC(=O)c1sc(cc1N2C(=O)C=CC2=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I08 compound treatment 0.329 0.0106 0.85 0.327 0.0147 1.34 1.5482 0.976 2076227 Maybridge3_001944 FC(F)(F)c1oc(cc1C(=O)Nc2cccnc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I09 compound treatment 0.322 0.00356 0.29 0.307 -0.00525 -0.48 -0.1341 -0.2411 1384468 Maybridge3_001945 Cc1cn(CCC(=O)NC2CCN(Cc3ccccc3)CC2)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I10 compound treatment 0.325 0.00656 0.53 0.321 0.00875 0.79 0.9353 0.9804 1575936 Maybridge3_001946 O=C(Nc1ccc2OCCOc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I11 compound treatment 0.329 0.0106 0.85 0.328 0.0158 1.43 1.6124 0.9692 1710950 Maybridge3_001947 Clc1ccc2nc(sc2c1)N3CCN(CC3)S(=O)(=O)c4ccc(C#N)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I12 compound treatment 0.312 -0.00644 -0.52 0.3 -0.0123 -1.11 -1.1528 -0.9397 2076228 Maybridge3_001948 FC(F)(F)c1cc(NC(=O)c2cccs2)ccc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I13 compound treatment 0.339 0.0206 1.66 0.325 0.0127 1.16 1.9892 0.9847 1193929 Maybridge3_001949 COc1ccc(cc1)c2ccnc(SCC(=O)N3CCN(CC3)c4ccccc4)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I14 compound treatment 0.321 0.00256 0.21 0.312 -2.5E-4 -0.02 0.1299 0.6256 1701310 Maybridge3_001950 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I15 compound treatment 0.309 -0.00944 -0.76 0.327 0.0147 1.34 0.4094 0.2659 1559476 Maybridge3_001951 COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I16 compound treatment 0.351 0.0326 2.62 0.348 0.0357 3.25 4.1488 0.9944 2076229 Maybridge3_001952 Cc1nc(nc(SCC(=O)c2ccccc2)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I17 compound treatment 0.338 0.0196 1.58 0.335 0.0227 2.07 2.5741 0.9911 2076230 Maybridge3_001953 COc1ccc(cc1)c2c(nn3c(=O)cc([nH]c23)C(C)(C)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I18 compound treatment 0.319 5.63E-4 0.05 0.311 -0.00125 -0.11 -0.0482 -0.3945 1182581 Maybridge3_001954 Cc1ccc2N(CC(=O)Nc3ccccc3)CCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I19 compound treatment 0.354 0.0356 2.86 0.35 0.0377 3.43 4.4479 0.996 1467907 Maybridge3_001955 Cc1csc2c(=O)sc(NC(=O)c3ccc(F)cc3Cl)nc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I20 compound treatment 0.335 0.0166 1.33 0.329 0.0168 1.52 2.0182 0.9979 1671543 Maybridge3_001956 Cc1cc(no1)C(=O)Nc2nn(C)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I21 compound treatment 0.327 0.00856 0.69 0.318 0.00575 0.52 0.8566 0.9906 2076231 Maybridge3_001957 Fc1ccc(cc1)c2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I22 compound treatment 0.33 0.0116 0.93 0.325 0.0127 1.16 1.4767 0.9942 2076232 Maybridge3_001958 COCc1cc(O)nc(SCCS(=O)(=O)c2ccc(Cl)cc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I23 mock treatment 0.323 0.00456 0.37 0.312 -2.5E-4 -0.02 0.2437 0.6622 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 I24 positive control 0.091 -0.227 -18.31 0.088 -0.224 -20.36 -27.344 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J01 compound treatment 0.327 0.00856 0.69 0.32 0.00775 0.7 0.985 0.9999 1485257 Maybridge3_001959 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)Nc3ccncc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J02 compound treatment 0.332 0.0136 1.09 0.32 0.00775 0.7 1.2697 0.9774 2076233 Maybridge3_001960 FC(F)(F)c1cc(n[nH]1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J03 compound treatment 0.328 0.00956 0.77 0.32 0.00775 0.7 1.0419 0.999 1134819 Maybridge3_001961 Cc1cc(no1)C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J04 compound treatment 0.334 0.0156 1.25 0.329 0.0168 1.52 1.9612 0.9954 1313849 Maybridge3_001962 O=C(NC1CCS(=O)(=O)C1)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J05 compound treatment 0.333 0.0146 1.17 0.326 0.0138 1.25 1.7117 0.9995 2076234 Maybridge3_001963 OCC(=O)c1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J06 compound treatment 0.332 0.0136 1.09 0.33 0.0177 1.61 1.9115 0.9821 2076235 Maybridge3_001964 O=C(Nc1cccnc1N2CCOCC2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J07 compound treatment 0.331 0.0126 1.01 0.323 0.0107 0.98 1.4053 0.9998 2076236 Maybridge3_001965 FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)c3cccs3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J08 compound treatment 0.33 0.0116 0.93 0.322 0.00975 0.89 1.2842 0.9997 2076237 Maybridge3_001966 Cc1cc(C)n2nc(c(c3ccccc3)c2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J09 compound treatment 0.349 0.0306 2.46 0.335 0.0227 2.07 3.2005 0.9962 1600185 Maybridge3_001967 COC(=O)C1=C(C)NC2=C(C1c3sccc3C)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J10 compound treatment 0.352 0.0336 2.7 0.349 0.0367 3.34 4.2699 0.9945 1579630 Maybridge3_001968 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J11 compound treatment 0.326 0.00756 0.61 0.322 0.00975 0.89 1.0564 0.9834 1495636 Maybridge3_001969 Fc1ccccc1CC(=O)Nc2nnc(s2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J12 compound treatment 0.333 0.0146 1.17 0.332 0.0198 1.79 2.0969 0.9788 1136115 Maybridge3_001970 Fc1ccc(NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J13 compound treatment 0.326 0.00756 0.61 0.32 0.00775 0.7 0.928 0.9974 1426078 Maybridge3_001971 COc1ccccc1n2c(coc2=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J14 compound treatment 0.332 0.0136 1.09 0.32 0.00775 0.7 1.2697 0.9774 1213217 Maybridge3_001972 Cn1nc(cc1C(=O)NCc2ccc3OCOc3c2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J15 compound treatment 0.325 0.00656 0.53 0.32 0.00775 0.7 0.8711 0.9901 1392939 Maybridge3_001973 OC(=O)CCCC(=O)Nc1ccc2COC(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J16 compound treatment 0.322 0.00356 0.29 0.317 0.00475 0.43 0.5077 0.9804 1543905 Maybridge3_001974 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J17 compound treatment 0.329 0.0106 0.85 0.327 0.0147 1.34 1.5482 0.976 1255998 Maybridge3_001975 O=c1nc([nH]c2ccccc12)c3cccc(Oc4ccccc4)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J18 compound treatment 0.354 0.0356 2.86 0.342 0.0297 2.7 3.9345 0.9996 1509089 Maybridge3_001976 CCCc1c(cnn1c2ccccc2)C(=O)NCc3ccc(OC)c(OC)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J19 compound treatment 0.32 0.00156 0.13 0.317 0.00475 0.43 0.3938 0.8769 1561840 Maybridge3_001977 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J20 compound treatment 0.326 0.00756 0.61 0.321 0.00875 0.79 0.9922 0.9914 1636335 Maybridge3_001978 COC(=O)c1ccc(n1C)S(=O)(=O)NCc2csc3ccc(Cl)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J21 compound treatment 0.332 0.0136 1.09 0.334 0.0217 1.97 2.1683 0.961 1214861 Maybridge3_001979 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3sccc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J22 compound treatment 0.323 0.00456 0.37 0.326 0.0138 1.25 1.1423 0.878 1481616 Maybridge3_001980 Cc1ccsc1CNC(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J23 mock treatment 0.317 -0.00144 -0.12 0.308 -0.00425 -0.39 -0.3546 -0.8805 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 J24 positive control 0.09 -0.228 -18.4 0.089 -0.223 -20.26 -27.3367 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K01 compound treatment 0.338 0.0196 1.58 0.323 0.0107 0.98 1.8039 0.9735 2076238 Maybridge3_001981 CN(C)c1ccc(cc1)n2nnnc2SC3Cc4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K02 compound treatment 0.34 0.0216 1.74 0.329 0.0168 1.52 2.3029 0.9978 2076239 Maybridge3_001982 Cc1nc(ccc1C(=O)Nc2nc3ccsc3c(=O)s2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K03 compound treatment 0.333 0.0146 1.17 0.33 0.0177 1.61 1.9685 0.9878 1438093 Maybridge3_001983 COC(=O)c1cc(NC(=O)c2ccccc2)ccc1N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K04 compound treatment 0.355 0.0366 2.94 0.355 0.0428 3.88 4.8258 0.9907 1667899 Maybridge3_001984 Cc1nnsc1C(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K05 compound treatment 0.326 0.00756 0.61 0.316 0.00375 0.34 0.6713 0.9622 1236304 Maybridge3_001985 Cc1ccc(OCC(O)CNC2Cc3ccccc3C2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K06 compound treatment 0.326 0.00756 0.61 0.323 0.0107 0.98 1.1206 0.9742 2076240 Maybridge3_001986 FC(F)(F)c1ccc(nc1)N2CCN(Cc3cc(Cl)cc4COCOc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K07 compound treatment 0.324 0.00556 0.45 0.33 0.0177 1.61 1.456 0.8707 1684322 Maybridge3_001987 OC(=O)c1nccnc1C(=O)N2CCCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K08 compound treatment 0.317 -0.00144 -0.12 0.326 0.0138 1.25 0.8007 0.6388 2076241 Maybridge3_001988 FC(F)(F)c1oc(cc1C(=O)Nc2ccncc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K09 compound treatment 0.316 -0.00244 -0.2 0.312 -2.5E-4 -0.02 -0.1548 -0.7836 1228424 Maybridge3_001989 Cc1cn(CCC(=O)Nc2ccc(F)cc2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K10 compound treatment 0.353 0.0346 2.78 0.344 0.0317 2.88 4.0059 0.9998 2076242 Maybridge3_001990 FC(F)(F)c1oc(cc1C(=O)NCc2ccncc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K11 compound treatment 0.335 0.0166 1.33 0.328 0.0158 1.43 1.954 0.9994 2076243 Maybridge3_001991 OC(=O)CSCC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K12 compound treatment 0.318 -4.37E-4 -0.04 0.313 7.5E-4 0.07 0.0232 0.303 1344374 Maybridge3_001992 CSc1ncccc1C(=O)NC2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K13 compound treatment 0.337 0.0186 1.49 0.328 0.0158 1.43 2.0679 0.9998 1538153 Maybridge3_001993 COc1cccc(SCC(=O)N2CCN(CC2)c3ccccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K14 compound treatment 0.352 0.0336 2.7 0.352 0.0398 3.61 4.4624 0.9899 1196604 Maybridge3_001994 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(F)cc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K15 compound treatment 0.34 0.0216 1.74 0.334 0.0217 1.97 2.6238 0.998 1607179 Maybridge3_001995 Cn1ncc2c(=O)sc(NC(=O)c3ccccc3)nc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K16 compound treatment 0.333 0.0146 1.17 0.332 0.0198 1.79 2.0969 0.9788 2076244 Maybridge3_001996 Cc1nc(nc(SCC(=O)N2CCOCC2)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K17 compound treatment 0.324 0.00556 0.45 0.324 0.0118 1.07 1.0709 0.9257 1397364 Maybridge3_001997 Cc1cn(CCC(=O)NCc2c(F)cccc2Cl)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K18 compound treatment 0.332 0.0136 1.09 0.319 0.00675 0.61 1.2055 0.9627 1576139 Maybridge3_001998 Cc1ccc(Oc2ncccc2NS(=O)(=O)C)c3CCCc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K19 compound treatment 0.355 0.0366 2.94 0.344 0.0317 2.88 4.1198 0.9999 1322535 Maybridge3_001999 Cc1csc2c(=O)sc(NC(=O)c3ccccc3C)nc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K20 compound treatment 0.323 0.00456 0.37 0.322 0.00975 0.89 0.8856 0.9242 2076245 Maybridge3_002000 Cn1nc(NC(=O)Cn2ccc(n2)C(F)(F)F)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K21 compound treatment 0.316 -0.00244 -0.2 0.316 0.00375 0.34 0.1019 0.2593 2076246 Maybridge3_002001 c1csc(c1)c2nc(cs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K22 compound treatment 0.32 0.00156 0.13 0.317 0.00475 0.43 0.3938 0.8769 1120927 Maybridge3_002002 Cc1c(cnn1c2ccc(Cl)cc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K23 mock treatment 0.32 0.00156 0.13 0.312 -2.5E-4 -0.02 0.0729 0.5704 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 K24 positive control 0.092 -0.226 -18.23 0.089 -0.223 -20.26 -27.2229 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L01 compound treatment 0.336 0.0176 1.41 0.327 0.0147 1.34 1.9468 0.9996 1404788 Maybridge3_002003 CC(=O)Nc1cccc(c1)n2nnc(SCc3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L02 compound treatment 0.332 0.0136 1.09 0.325 0.0127 1.16 1.5906 0.9996 1467506 Maybridge3_002004 Fc1cc(CNC(=O)c2ccc(s2)c3ccccn3)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L03 compound treatment 0.332 0.0136 1.09 0.331 0.0187 1.7 1.9757 0.977 1607688 Maybridge3_002005 COc1ccc(cc1OC)C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L04 compound treatment 0.345 0.0266 2.14 0.342 0.0297 2.7 3.422 0.9933 1731758 Maybridge3_002006 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2nc3cc(Cl)ccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L05 compound treatment 0.334 0.0156 1.25 0.323 0.0107 0.98 1.5761 0.9923 2076247 Maybridge3_002007 Cn1c(SCC(=O)c2ccc(F)cc2)nnc1c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L06 compound treatment 0.337 0.0186 1.49 0.336 0.0238 2.16 2.5814 0.984 1142775 Maybridge3_002008 Clc1cc(C(=O)Nc2nnc(s2)C3CC3)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L07 compound treatment 0.33 0.0116 0.93 0.324 0.0118 1.07 1.4126 0.9977 1287211 Maybridge3_002009 CC1CCN(CC1)c2nc(ns2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L08 compound treatment 0.328 0.00956 0.77 0.324 0.0118 1.07 1.2987 0.9872 1489531 Maybridge3_002010 Cc1cnc(NS(=O)(=O)c2cn(C)cn2)c(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L09 compound treatment 0.345 0.0266 2.14 0.345 0.0327 2.97 3.6146 0.987 2076248 Maybridge3_002011 OC1CCN(CC1)S(=O)(=O)c2ccc(Oc3cccc(Cl)c3C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L10 compound treatment 0.345 0.0266 2.14 0.338 0.0257 2.34 3.1653 0.999 1403249 Maybridge3_002012 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L11 compound treatment 0.322 0.00356 0.29 0.328 0.0158 1.43 1.2138 0.8324 1735185 Maybridge3_002013 COc1ccc(cc1)C(=O)NC2CCS(=O)(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L12 compound treatment 0.33 0.0116 0.93 0.334 0.0217 1.97 2.0544 0.9412 1441094 Maybridge3_002014 O=C(Oc1ccccc1N2CCOCC2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L13 compound treatment 0.328 0.00956 0.77 0.328 0.0158 1.43 1.5554 0.9579 1580635 Maybridge3_002015 OC(=O)COCC(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L14 compound treatment 0.319 5.63E-4 0.05 0.323 0.0107 0.98 0.722 0.7391 2076249 Maybridge3_002016 O=c1[nH]cnc2sc3CCN(Cc4ccccc4)Cc3c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L15 compound treatment 0.331 0.0126 1.01 0.327 0.0147 1.34 1.662 0.9904 1129175 Maybridge3_002017 CC(C)(CC(=O)O)CC(=O)Nc1ccc2COC(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L16 compound treatment 0.343 0.0246 1.98 0.334 0.0217 1.97 2.7946 1.0 2076250 Maybridge3_002018 COC(=O)c1cc(c(s1)C(F)(F)F)c2ccc(cc2)S(=O)(=O)NCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L17 compound treatment 0.333 0.0146 1.17 0.32 0.00775 0.7 1.3266 0.9701 1331961 Maybridge3_002019 Oc1ccc(cc1)c2nc(=O)c3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L18 compound treatment 0.335 0.0166 1.33 0.321 0.00875 0.79 1.5047 0.9693 1712584 Maybridge3_002020 COc1cccc2n(C)nc(NC(=O)c3cc(C)oc3C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L19 compound treatment 0.325 0.00656 0.53 0.324 0.0118 1.07 1.1278 0.9475 1495236 Maybridge3_002021 O=C(NCc1ccco1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L20 compound treatment 0.332 0.0136 1.09 0.326 0.0138 1.25 1.6548 0.9978 1486898 Maybridge3_002022 Clc1ccc2scc(CNS(=O)(=O)c3ccc(cc3)N4C(=O)CCC4=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L21 compound treatment 0.341 0.0226 1.82 0.341 0.0288 2.61 3.13 0.9843 1492659 Maybridge3_002023 O=C(NC1Cc2ccccc2C1)C3CCN(CC3)C(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L22 compound treatment 0.324 0.00556 0.45 0.32 0.00775 0.7 0.8142 0.9762 2076251 Maybridge3_002024 Cc1ccsc1CNS(=O)(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L23 mock treatment 0.322 0.00356 0.29 0.315 0.00275 0.25 0.3794 0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 L24 positive control 0.094 -0.224 -18.07 0.09 -0.222 -20.17 -27.0448 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M01 compound treatment 0.324 0.00556 0.45 0.315 0.00275 0.25 0.4932 0.9619 1337273 Maybridge3_002025 OC(CNCc1ccc2OCOc2c1)CSc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M02 compound treatment 0.324 0.00556 0.45 0.313 7.5E-4 0.07 0.3649 0.8053 1270387 Maybridge3_002026 O=C(NC1CCN(Cc2ccccc2)CC1)c3cccn3CCc4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M03 compound treatment 0.31 -0.00844 -0.68 0.314 0.00175 0.16 -0.3681 -0.5276 2076252 Maybridge3_002027 OC(CN1CCN(CC1)C(c2ccccc2)c3ccccc3)Oc4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M04 compound treatment 0.328 0.00956 0.77 0.323 0.0107 0.98 1.2345 0.9931 1432356 Maybridge3_002028 Cc1nnsc1C(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M05 compound treatment 0.326 0.00756 0.61 0.304 -0.00825 -0.75 -0.0989 -0.1025 1440931 Maybridge3_002029 OC(CNC1Cc2ccccc2C1)COc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M06 compound treatment 0.327 0.00856 0.69 0.318 0.00575 0.52 0.8566 0.9906 2076253 Maybridge3_002030 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M07 compound treatment 0.324 0.00556 0.45 0.319 0.00675 0.61 0.75 0.9881 1712757 Maybridge3_002031 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M08 compound treatment 0.308 -0.0104 -0.84 0.304 -0.00825 -0.75 -1.1238 -0.9983 1427520 Maybridge3_002032 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M09 compound treatment 0.324 0.00556 0.45 0.319 0.00675 0.61 0.75 0.9881 1540055 Maybridge3_002033 Cc1cn(CCC(=O)NCc2ccc3OCOc3c2)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M10 compound treatment 0.323 0.00456 0.37 0.318 0.00575 0.52 0.6289 0.9852 1683280 Maybridge3_002034 O=C(Nc1ccc2OCCOc2c1)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M11 compound treatment 0.344 0.0256 2.06 0.34 0.0278 2.52 3.2367 0.995 1650787 Maybridge3_002035 Fc1ccc(cc1)C(=O)N2CCCN(CC2)c3nc(ns3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M12 compound treatment 0.315 -0.00344 -0.28 0.309 -0.00325 -0.3 -0.4043 -0.9995 1181430 Maybridge3_002036 Cc1ccc(cn1)C(=O)NC2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M13 compound treatment 0.329 0.0106 0.85 0.321 0.00875 0.79 1.1631 0.9994 1511362 Maybridge3_002037 CCCc1cc(O)nc(SCC(=O)N2CCN(CC2)c3ccccc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M14 compound treatment 0.33 0.0116 0.93 0.325 0.0127 1.16 1.4767 0.9942 1446041 Maybridge3_002038 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2cccs2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M15 compound treatment 0.325 0.00656 0.53 0.32 0.00775 0.7 0.8711 0.9901 1235452 Maybridge3_002039 Brc1cc(Br)c2nc(NC(=O)c3cccs3)sc(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M16 compound treatment 0.328 0.00956 0.77 0.32 0.00775 0.7 1.0419 0.999 1696431 Maybridge3_002040 CC(=O)Nc1ccc(Oc2nc(ns2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M17 compound treatment 0.337 0.0186 1.49 0.334 0.0217 1.97 2.453 0.9906 1512525 Maybridge3_002041 Cc1cn(CCC(=O)Nc2nn(C)c3ccccc23)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M18 compound treatment 0.34 0.0216 1.74 0.34 0.0278 2.52 3.0089 0.9835 1250808 Maybridge3_002042 O=C(N(Cc1ccccn1)Cc2ccccn2)c3cc4ccccc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M19 compound treatment 0.335 0.0166 1.33 0.332 0.0198 1.79 2.2107 0.9894 2076254 Maybridge3_002043 CCn1nc(C)cc1C(=O)OCC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M20 compound treatment 0.323 0.00456 0.37 0.316 0.00375 0.34 0.5005 0.9993 1495118 Maybridge3_002044 CN(C)S(=O)(=O)c1cc(C(=O)Nc2ccc(Cl)cc2)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M21 compound treatment 0.336 0.0176 1.41 0.337 0.0248 2.25 2.5886 0.9751 2076255 Maybridge3_002045 Cc1csc2c(=O)sc(NC(=O)c3ccc(OC(F)(F)F)cc3)nc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M22 compound treatment 0.353 0.0346 2.78 0.352 0.0398 3.61 4.5194 0.9918 1735321 Maybridge3_002046 Cc1c(cnn1c2ccc(Cl)cc2)C(=O)N(Cc3ccccc3)Cc4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M23 mock treatment 0.317 -0.00144 -0.12 0.31 -0.00225 -0.2 -0.2263 -0.9638 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 M24 positive control 0.093 -0.225 -18.15 0.091 -0.221 -20.08 -27.0375 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N01 compound treatment 0.336 0.0176 1.41 0.34 0.0278 2.52 2.7812 0.9627 2076256 Maybridge3_002047 CCOC(=O)Cc1c(C)nn(c1O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N02 compound treatment 0.337 0.0186 1.49 0.328 0.0158 1.43 2.0679 0.9998 1522088 Maybridge3_002048 Fc1cc(CNC(=O)C2CC2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N03 compound treatment 0.334 0.0156 1.25 0.328 0.0158 1.43 1.8971 0.9978 1207786 Maybridge3_002049 OC(=O)CSCC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N04 compound treatment 0.339 0.0206 1.66 0.334 0.0217 1.97 2.5669 0.9962 1154839 Maybridge3_002050 OC(=O)CSCC(=O)N1CCN(CC1)c2nc3cc(Cl)ccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N05 compound treatment 0.332 0.0136 1.09 0.325 0.0127 1.16 1.5906 0.9996 1740795 Maybridge3_002051 O=S(=O)(NCC1CCN(CC1)S(=O)(=O)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N06 compound treatment 0.335 0.0166 1.33 0.334 0.0217 1.97 2.3391 0.9818 1617862 Maybridge3_002052 Clc1c(sc2ccccc12)C(=O)Nc3nnc(s3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N07 compound treatment 0.357 0.0386 3.11 0.357 0.0447 4.06 5.0681 0.9912 1364637 Maybridge3_002053 COC(=O)C1=C(C)NC2=C(C1c3ccc(cc3Cl)N(C)C)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N08 compound treatment 0.356 0.0376 3.02 0.362 0.0498 4.52 5.332 0.981 1440607 Maybridge3_002054 Cc1csc(NC(=O)CSCC(=O)O)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N09 compound treatment 0.328 0.00956 0.77 0.334 0.0217 1.97 1.9405 0.9157 1446222 Maybridge3_002055 Cn1cc(Br)c(n1)c2cccc(NC(=O)CCCC(=O)O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N10 compound treatment 0.348 0.0296 2.38 0.345 0.0327 2.97 3.7854 0.9939 1490229 Maybridge3_002056 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OC(C)(C)CCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N11 compound treatment 0.326 0.00756 0.61 0.328 0.0158 1.43 1.4415 0.9277 1255021 Maybridge3_002057 O=S(=O)(NC1CCS(=O)(=O)C1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N12 compound treatment 0.341 0.0226 1.82 0.328 0.0158 1.43 2.2956 0.993 2076257 Maybridge3_002058 Cc1nc(ccc1C(=O)Oc2ccccc2N3CCOCC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N13 compound treatment 0.332 0.0136 1.09 0.324 0.0118 1.07 1.5264 0.9999 1456078 Maybridge3_002059 OC(=O)CCC(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N14 compound treatment 0.333 0.0146 1.17 0.33 0.0177 1.61 1.9685 0.9878 1595423 Maybridge3_002060 OC(=O)CCc1nc(no1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N15 compound treatment 0.325 0.00656 0.53 0.327 0.0147 1.34 1.3204 0.9173 1731731 Maybridge3_002061 CSc1ncccc1C(=O)Nc2ccc3COC(=O)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N16 compound treatment 0.341 0.0226 1.82 0.332 0.0198 1.79 2.5524 1.0 2076258 Maybridge3_002062 COC(=O)c1cc(c(s1)C(F)(F)F)c2ccc(cc2)S(=O)(=O)NCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N17 compound treatment 0.358 0.0396 3.19 0.35 0.0377 3.43 4.6757 0.9993 1199121 Maybridge3_002063 COc1ccccc1C2CCN(CC2)C(=O)c3cnn(c3C)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N18 compound treatment 0.353 0.0346 2.78 0.347 0.0347 3.15 4.1984 0.9981 1505166 Maybridge3_002064 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N19 compound treatment 0.324 0.00556 0.45 0.322 0.00975 0.89 0.9425 0.9502 1717636 Maybridge3_002065 O=C(NCc1ccsc1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N20 compound treatment 0.316 -0.00244 -0.2 0.318 0.00575 0.52 0.2303 0.413 1731432 Maybridge3_002066 CCN(CC)c1ccc(NS(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N21 compound treatment 0.334 0.0156 1.25 0.327 0.0147 1.34 1.8329 0.9995 2076259 Maybridge3_002067 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(s3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N22 compound treatment 0.324 0.00556 0.45 0.327 0.0147 1.34 1.2635 0.8949 2076260 Maybridge3_002068 Cc1ccsc1CNS(=O)(=O)c2cccc3nonc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N23 mock treatment 0.32 0.00156 0.13 0.314 0.00175 0.16 0.2013 0.9933 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 N24 positive control 0.092 -0.226 -18.23 0.091 -0.221 -20.08 -27.0945 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O01 compound treatment 0.341 0.0226 1.82 0.337 0.0248 2.25 2.8733 0.9945 1261462 Maybridge3_002069 NC(=O)C1CCN(CC(O)CSc2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O02 compound treatment 0.352 0.0336 2.7 0.343 0.0308 2.79 3.8848 0.9999 2076261 Maybridge3_002070 COC(=O)Cc1cc(=O)n2nc(c(c3ccc(Br)cc3)c2[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O03 compound treatment 0.328 0.00956 0.77 0.328 0.0158 1.43 1.5554 0.9579 1419421 Maybridge3_002071 OC(CNCc1ccc2OCOc2c1)COc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O04 compound treatment 0.336 0.0176 1.41 0.327 0.0147 1.34 1.9468 0.9996 1587400 Maybridge3_002072 Cc1nnsc1C(=O)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O05 compound treatment 0.342 0.0236 1.9 0.336 0.0238 2.16 2.8661 0.998 2076262 Maybridge3_002073 Cc1ccc(Sc2ncccc2c3nnc(o3)C4CC4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O06 compound treatment 0.371 0.0526 4.23 0.365 0.0527 4.79 6.3787 0.9981 1681752 Maybridge3_002074 COC(=O)c1sc(cc1NC(=O)CCC(=O)O)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O07 compound treatment 0.316 -0.00244 -0.2 0.326 0.0138 1.25 0.7438 0.5887 1380844 Maybridge3_002075 COc1ccc2[nH]c(cc2c1)C(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O08 compound treatment 0.34 0.0216 1.74 0.324 0.0118 1.07 1.982 0.9726 2076263 Maybridge3_002076 FC(F)(F)c1ccccc1C(=O)N2CCCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O09 compound treatment 0.331 0.0126 1.01 0.328 0.0158 1.43 1.7262 0.9857 1423981 Maybridge3_002077 COc1ccc(NC(=O)CCn2cc(C)c3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O10 compound treatment 0.349 0.0306 2.46 0.344 0.0317 2.88 3.7781 0.9969 1154956 Maybridge3_002078 OC(=O)CSCC(=O)N1CCCN(CC1)c2nc3ccc(Cl)cc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O11 compound treatment 0.335 0.0166 1.33 0.33 0.0177 1.61 2.0824 0.9956 1599738 Maybridge3_002079 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O12 compound treatment 0.333 0.0146 1.17 0.336 0.0238 2.16 2.3536 0.959 1229630 Maybridge3_002080 Cc1cc(ccc1NC(=O)CSCC(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O13 compound treatment 0.344 0.0256 2.06 0.343 0.0308 2.79 3.4292 0.9888 2076264 Maybridge3_002081 Cc1nc(ccc1C(=O)Nc2oc(cc2C#N)c3ccccc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O14 compound treatment 0.344 0.0256 2.06 0.343 0.0308 2.79 3.4292 0.9888 1208774 Maybridge3_002082 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccs2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O15 compound treatment 0.332 0.0136 1.09 0.322 0.00975 0.89 1.3981 0.9946 1242858 Maybridge3_002083 COc1ccc(NC(=O)c2cccs2)cc1OC3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O16 compound treatment 0.33 0.0116 0.93 0.325 0.0127 1.16 1.4767 0.9942 2076265 Maybridge3_002084 COc1ncnc2scc(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O17 compound treatment 0.339 0.0206 1.66 0.336 0.0238 2.16 2.6952 0.9915 1676392 Maybridge3_002085 OC(=O)CSCC(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O18 compound treatment 0.342 0.0236 1.9 0.328 0.0158 1.43 2.3526 0.9903 2076266 Maybridge3_002086 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)C(=O)c3cc4ccccc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O19 compound treatment 0.327 0.00856 0.69 0.328 0.0158 1.43 1.4985 0.9441 1094519 Maybridge3_002087 CC(=O)N1CCCC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O20 compound treatment 0.33 0.0116 0.93 0.323 0.0107 0.98 1.3484 0.9997 1432005 Maybridge3_002088 O=S(=O)(Nc1ccccc1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O21 compound treatment 0.39 0.0716 5.76 0.378 0.0658 5.97 8.295 0.9998 2076267 Maybridge3_002089 CN1CCc2c(C1)sc3nc(NC(=O)c4ccc(OC(F)(F)F)cc4)sc(=O)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O22 compound treatment 0.349 0.0306 2.46 0.34 0.0278 2.52 3.5214 0.9999 1162914 Maybridge3_002090 Cc1cn(CCC(=O)Nc2ccccc2N3CCOCC3)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O23 mock treatment 0.329 0.0106 0.85 0.318 0.00575 0.52 0.9705 0.9725 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 O24 positive control 0.093 -0.225 -18.15 0.092 -0.22 -19.99 -26.9734 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P01 compound treatment 0.329 0.0106 0.85 0.332 0.0198 1.79 1.8691 0.942 2076268 Maybridge3_002091 FC(F)(F)c1oc(cc1C(=O)NC2CCS(=O)(=O)C2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P02 compound treatment 0.335 0.0166 1.33 0.33 0.0177 1.61 2.0824 0.9956 1339238 Maybridge3_002092 Fc1cc(CNC(=O)c2ccno2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P03 compound treatment 0.329 0.0106 0.85 0.333 0.0208 1.88 1.9333 0.9355 1398003 Maybridge3_002093 CC(C)(CC(=O)O)CC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P04 compound treatment 0.326 0.00756 0.61 0.325 0.0127 1.16 1.249 0.955 2076269 Maybridge3_002094 OC(=O)CCCC(=O)Nc1ccccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P05 compound treatment 0.329 0.0106 0.85 0.32 0.00775 0.7 1.0989 0.9956 1727748 Maybridge3_002095 Fc1ccc(cc1F)c2csc(NS(=O)(=O)c3cccs3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P06 compound treatment 0.33 0.0116 0.93 0.323 0.0107 0.98 1.3484 0.9997 1723918 Maybridge3_002096 OC(=O)C1CCC1C(=O)Nc2nnc(s2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P07 compound treatment 0.32 0.00156 0.13 0.323 0.0107 0.98 0.779 0.7917 1566497 Maybridge3_002097 COc1cccc2n(C)nc(NC(=O)c3cc4ccccc4s3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P08 compound treatment 0.357 0.0386 3.11 0.357 0.0447 4.06 5.0681 0.9912 2076270 Maybridge3_002098 OC(=O)CSCC(=O)Nc1ccccc1Sc2ncnc3cc(sc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P09 compound treatment 0.329 0.0106 0.85 0.326 0.0138 1.25 1.484 0.9825 1647183 Maybridge3_002099 Cn1cc(Br)c(n1)c2cccc(NC(=O)CSCC(=O)O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P10 compound treatment 0.362 0.0436 3.51 0.355 0.0428 3.88 5.2244 0.9987 2076271 Maybridge3_002100 COC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(=O)O)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P11 compound treatment 0.324 0.00556 0.45 0.317 0.00475 0.43 0.6216 0.9998 1266414 Maybridge3_002101 CCCCc1ccc(cc1)S(=O)(=O)NC2CCS(=O)(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P12 compound treatment 0.33 0.0116 0.93 0.321 0.00875 0.79 1.22 0.9969 2076272 Maybridge3_002102 CSc1nsc(SC)c1C(=O)Oc2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P13 compound treatment 0.326 0.00756 0.61 0.322 0.00975 0.89 1.0564 0.9834 1725821 Maybridge3_002103 CC(C)(CC(=O)O)CC(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P14 compound treatment 0.33 0.0116 0.93 0.322 0.00975 0.89 1.2842 0.9997 1192346 Maybridge3_002104 O=C(NCc1ccc2OCOc2c1)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P15 compound treatment 0.322 0.00356 0.29 0.322 0.00975 0.89 0.8287 0.8907 1182512 Maybridge3_002105 O=C(CCc1ccccc1)Nc2ccc3COC(=O)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P16 compound treatment 0.325 0.00656 0.53 0.322 0.00975 0.89 0.9995 0.9696 1469354 Maybridge3_002106 OC(=O)c1nccnc1C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P17 compound treatment 0.333 0.0146 1.17 0.327 0.0147 1.34 1.7759 0.9978 2076273 Maybridge3_002107 FC(F)(F)c1nn2c(=O)cc([nH]c2c1c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P18 compound treatment 0.353 0.0346 2.78 0.356 0.0437 3.97 4.7761 0.9849 1626757 Maybridge3_002108 COC(=O)C1=C(C)NC2=C(C1c3ccccc3N4CCOCC4)C(=O)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P19 compound treatment 0.325 0.00656 0.53 0.325 0.0127 1.16 1.192 0.9369 1654342 Maybridge3_002109 OCCCC(=O)NC1Cc2ccccc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P20 compound treatment 0.354 0.0356 2.86 0.344 0.0317 2.88 4.0628 1.0 1704763 Maybridge3_002110 CCN(CC)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P21 compound treatment 0.331 0.0126 1.01 0.331 0.0187 1.7 1.9188 0.9691 1313402 Maybridge3_002111 CC1=C(C#N)C(C2=C(CCCC2=O)N1)c3c[nH]nc3c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P22 compound treatment 0.324 0.00556 0.45 0.321 0.00875 0.79 0.8784 0.9633 1296036 Maybridge3_002112 Cc1ccsc1CNS(=O)(=O)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P23 mock treatment 0.319 5.63E-4 0.05 0.315 0.00275 0.25 0.2085 0.822 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1436 P24 positive control 0.094 -0.224 -18.07 0.093 -0.219 -19.9 -26.8522 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A01 compound treatment 0.312 -0.00725 -0.58 0.314 -0.00725 -0.66 -0.8782 -0.9982 2076274 Maybridge3_002113 Cc1ccsc1CNC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A02 compound treatment 0.323 0.00375 0.3 0.323 0.00175 0.16 0.3259 0.955 1642395 Maybridge3_002114 Cc1cc(NC(=O)CC2(CC(=O)O)CCCC2)n(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A03 compound treatment 0.309 -0.0103 -0.83 0.309 -0.0123 -1.11 -1.3699 -0.9892 1645580 Maybridge3_002115 OC(CN1CCN(Cc2ccc3OCOc3c2)CC1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A04 compound treatment 0.308 -0.0113 -0.91 0.31 -0.0113 -1.02 -1.3627 -0.9982 2076275 Maybridge3_002116 Cc1cc(no1)C(=O)Nc2c(c(nn2C)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A05 compound treatment 0.309 -0.0103 -0.83 0.312 -0.00925 -0.84 -1.1774 -1.0 1667979 Maybridge3_002117 CCCc1c(cnn1c2ccccc2)C(=O)NCc3cc(F)cc4COCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A06 compound treatment 0.305 -0.0143 -1.15 0.31 -0.0113 -1.02 -1.5335 -0.9983 2076276 Maybridge3_002118 Cc1ccc(cc1)c2cn3cccnc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A07 compound treatment 0.322 0.00275 0.22 0.319 -0.00225 -0.2 0.0122 0.0404 1218131 Maybridge3_002119 Clc1ccc2scc(CNS(=O)(=O)c3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A08 compound treatment 0.303 -0.0163 -1.31 0.307 -0.0143 -1.29 -1.8399 -1.0 2076277 Maybridge3_002120 FC(F)(F)c1ccc(nc1)N2CCN(Cc3c[nH]c4ccccc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A09 compound treatment 0.301 -0.0182 -1.47 0.304 -0.0173 -1.57 -2.1464 -0.9995 1136955 Maybridge3_002121 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A10 compound treatment 0.377 0.0578 4.65 0.368 0.0468 4.24 6.289 0.999 2076278 Maybridge3_002122 OC(=O)CC1SC(=NC1=O)c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A11 compound treatment 0.308 -0.0113 -0.91 0.308 -0.0133 -1.2 -1.491 -0.9902 1510621 Maybridge3_002123 Cc1cc(C(=O)NCc2ccc3OCOc3c2)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A12 compound treatment 0.315 -0.00425 -0.34 0.314 -0.00725 -0.66 -0.7073 -0.9536 1540339 Maybridge3_002124 O=C(N1CCN(CC1)c2ncccc2C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A13 compound treatment 0.311 -0.00825 -0.66 0.309 -0.0123 -1.11 -1.256 -0.9697 2076279 Maybridge3_002125 CC(C)NC(=O)CSc1nccc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A14 compound treatment 0.306 -0.0133 -1.07 0.307 -0.0143 -1.29 -1.6691 -0.9954 1172579 Maybridge3_002126 COc1ccc(OCC(O)CNC(=O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A15 compound treatment 0.309 -0.0103 -0.83 0.308 -0.0133 -1.2 -1.4341 -0.9831 1271788 Maybridge3_002127 CC(C)c1ccc(NC(=O)CSc2ncccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A16 compound treatment 0.311 -0.00825 -0.66 0.311 -0.0103 -0.93 -1.1277 -0.9864 2076280 Maybridge3_002128 OC(=O)CC1(CC(=O)Nc2ccc(C#N)cc2)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A17 compound treatment 0.305 -0.0143 -1.15 0.306 -0.0153 -1.38 -1.7902 -0.9957 1121883 Maybridge3_002129 OC(=O)c1ccccc1C(=O)Nc2ncccc2OCc3ccc(Cl)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A18 compound treatment 0.311 -0.00825 -0.66 0.315 -0.00625 -0.57 -0.8709 -0.9969 2076281 Maybridge3_002130 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A19 compound treatment 0.313 -0.00625 -0.5 0.315 -0.00625 -0.57 -0.757 -0.9982 2076282 Maybridge3_002131 Cc1cc(no1)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A20 compound treatment 0.322 0.00275 0.22 0.321 -2.5E-4 -0.02 0.1405 0.6313 1335869 Maybridge3_002132 OC(=O)CCC(=O)NCc1c(Cl)cccc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A21 compound treatment 0.335 0.0158 1.27 0.334 0.0127 1.16 1.7152 0.999 1170358 Maybridge3_002133 COc1ccc(CNC(=O)c2cc(oc2C)C(C)(C)C)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A22 compound treatment 0.301 -0.0182 -1.47 0.304 -0.0173 -1.57 -2.1464 -0.9995 1482278 Maybridge3_002134 CCc1ccn2cc(nc2c1)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A23 mock treatment 0.301 -0.0182 -1.47 0.305 -0.0163 -1.48 -2.0822 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 A24 positive control 0.081 -0.238 -19.19 0.081 -0.24 -21.81 -28.9866 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B01 compound treatment 0.321 0.00175 0.14 0.325 0.00375 0.34 0.3403 0.9238 1234783 Maybridge3_002135 Cc1ccc(CSCC(=O)NCc2ccc3OCOc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B02 compound treatment 0.331 0.0118 0.95 0.332 0.0107 0.98 1.359 0.9999 1677511 Maybridge3_002136 Cc1nnsc1C(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B03 compound treatment 0.33 0.0107 0.87 0.331 0.00975 0.89 1.2379 0.9999 1701952 Maybridge3_002137 Cc1cccc(NC(=O)C2CCC2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B04 compound treatment 0.328 0.00875 0.7 0.328 0.00675 0.61 0.9315 0.9976 1506143 Maybridge3_002138 OC(=O)CCC(=O)Nc1ccccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B05 compound treatment 0.328 0.00875 0.7 0.328 0.00675 0.61 0.9315 0.9976 1306599 Maybridge3_002139 Cc1cccc2nc(oc(=O)c12)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B06 compound treatment 0.315 -0.00425 -0.34 0.323 0.00175 0.16 -0.1297 -0.3437 2076283 Maybridge3_002140 FC(F)(F)c1ccnc(c1)N2CCN(Cc3c[nH]c4ccccc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B07 compound treatment 0.325 0.00575 0.46 0.323 0.00175 0.16 0.4397 0.8983 2076284 Maybridge3_002141 Cc1nc(ccc1C(=O)NC2CCCc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B08 compound treatment 0.326 0.00675 0.54 0.327 0.00575 0.52 0.7534 0.9998 2076285 Maybridge3_002142 COc1ccc(SCCc2nnc(o2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B09 compound treatment 0.316 -0.00325 -0.26 0.317 -0.00425 -0.39 -0.4578 -0.9821 1191136 Maybridge3_002143 COc1ccccc1C2CCN(Cc3c[nH]nc3c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B10 compound treatment 0.327 0.00775 0.62 0.326 0.00475 0.43 0.7462 0.9837 1161266 Maybridge3_002144 Cn1nccc1NC(=O)CCCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B11 compound treatment 0.322 0.00275 0.22 0.322 7.5E-4 0.07 0.2047 0.8837 2076286 Maybridge3_002145 CC1Sc2ccc(Cl)cc2-c3nc(ncc13)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B12 compound treatment 0.322 0.00275 0.22 0.322 7.5E-4 0.07 0.2047 0.8837 2076287 Maybridge3_002146 O=S(=O)(N(CCC#N)Cc1cccs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B13 compound treatment 0.327 0.00775 0.62 0.329 0.00775 0.7 0.9387 0.9982 1507733 Maybridge3_002147 Cn1cnc(c1)S(=O)(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B14 compound treatment 0.329 0.00975 0.79 0.331 0.00975 0.89 1.181 0.9982 1732250 Maybridge3_002148 COc1cc2CCN(C(C)c2cc1OC)C(=O)CSCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B15 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 1502412 Maybridge3_002149 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B16 compound treatment 0.35 0.0308 2.48 0.35 0.0288 2.61 3.5963 0.9997 1660311 Maybridge3_002150 Cc1onc(c1C(=O)Oc2ccccc2N3CCOCC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B17 compound treatment 0.328 0.00875 0.7 0.329 0.00775 0.7 0.9957 1.0 1233574 Maybridge3_002151 OC(CNC(=O)c1cccs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B18 compound treatment 0.324 0.00475 0.38 0.33 0.00875 0.79 0.8321 0.9439 1468929 Maybridge3_002152 OC(=O)CCCC(=O)NC1CCCCNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B19 compound treatment 0.32 7.5E-4 0.06 0.325 0.00375 0.34 0.2834 0.8198 1177295 Maybridge3_002153 CCc1ccc(cc1)S(=O)(=O)NCC(O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B20 compound treatment 0.35 0.0308 2.48 0.348 0.0267 2.43 3.4679 1.0 1132169 Maybridge3_002154 CCOC(=O)c1cc(C)nc(N2CCCCC2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B21 compound treatment 0.33 0.0107 0.87 0.33 0.00875 0.79 1.1737 0.9991 1274928 Maybridge3_002155 COc1ccc(NC(=O)CC(CC(=O)O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B22 compound treatment 0.325 0.00575 0.46 0.326 0.00475 0.43 0.6323 0.9994 1310319 Maybridge3_002156 OC(=O)C1CCN(CC1)C(=O)C2CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B23 mock treatment 0.318 -0.00125 -0.1 0.322 7.5E-4 0.07 -0.023 -0.1896 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 B24 positive control 0.082 -0.237 -19.1 0.082 -0.239 -21.72 -28.8655 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C01 compound treatment 0.333 0.0138 1.11 0.333 0.0118 1.07 1.5371 0.9998 2076288 Maybridge3_002157 FC(F)(F)c1cc(c2cccs2)n(n1)c3ccc(NC(=O)c4ccno4)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C02 compound treatment 0.327 0.00775 0.62 0.33 0.00875 0.79 1.0029 0.9929 1226796 Maybridge3_002158 CC(C)(CC(=O)O)CC(=O)Nc1ccc(CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C03 compound treatment 0.309 -0.0103 -0.83 0.31 -0.0113 -1.02 -1.3057 -0.9944 1738736 Maybridge3_002159 OC(CSc1ccccc1)CN2CCN(Cc3ccc4OCOc4c3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C04 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 2076289 Maybridge3_002160 Cn1nc(c(c1NS(=O)(=O)C)c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C05 compound treatment 0.326 0.00675 0.54 0.333 0.0118 1.07 1.1385 0.9511 1398560 Maybridge3_002161 Cn1nc(cc1C(=O)NCc2cc(F)cc3COCOc23)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C06 compound treatment 0.323 0.00375 0.3 0.328 0.00675 0.61 0.6468 0.9469 1528878 Maybridge3_002162 N#Cc1ccc(cc1)c2cn3cccnc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C07 compound treatment 0.315 -0.00425 -0.34 0.315 -0.00625 -0.57 -0.6432 -0.9707 1608967 Maybridge3_002163 Cn1cnc(c1)S(=O)(=O)NCc2csc3ccc(Cl)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C08 compound treatment 0.277 -0.0423 -3.4 0.298 -0.0233 -2.11 -3.8981 -0.9736 1720976 Maybridge3_002164 COc1ccc2N(Cc3c[nH]c4ccccc34)CCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C09 compound treatment 0.314 -0.00525 -0.42 0.316 -0.00525 -0.48 -0.6359 -0.9982 2076290 Maybridge3_002165 Cc1ccsc1CNC(=O)c2sccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C10 compound treatment 0.384 0.0648 5.21 0.393 0.0717 6.51 8.2922 0.9939 1601798 Maybridge3_002166 OC(=O)CC1SC(=NC1=O)c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C11 compound treatment 0.329 0.00975 0.79 0.33 0.00875 0.79 1.1168 1.0 1585476 Maybridge3_002167 Cc1cc(NC(=O)c2cc(C)oc2C)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C12 compound treatment 0.331 0.0118 0.95 0.33 0.00875 0.79 1.2307 0.9962 1530641 Maybridge3_002168 COc1cccc(c1)C(=O)N2CCN(CC2)c3ncccc3C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C13 compound treatment 0.314 -0.00525 -0.42 0.323 0.00175 0.16 -0.1866 -0.4132 1701371 Maybridge3_002169 O=C(CSc1nccc(n1)c2cccs2)c3ccc4OCCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C14 compound treatment 0.324 0.00475 0.38 0.321 -2.5E-4 -0.02 0.2544 0.664 2076291 Maybridge3_002170 COc1ccc(OCC(O)CNC(=O)c2ccc(nc2C)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C15 compound treatment 0.32 7.5E-4 0.06 0.327 0.00575 0.52 0.4118 0.7837 2076292 Maybridge3_002171 Fc1ccc(cc1)S(=O)(=O)CCSc2ncccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C16 compound treatment 0.321 0.00175 0.14 0.33 0.00875 0.79 0.6613 0.8198 1175839 Maybridge3_002172 O=C(Nc1ccc(C#N)cc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C17 compound treatment 0.311 -0.00825 -0.66 0.32 -0.00125 -0.11 -0.55 -0.8161 1297760 Maybridge3_002173 OC(=O)CCC(=O)Nc1ncccc1OCc2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C18 compound treatment 0.325 0.00575 0.46 0.321 -2.5E-4 -0.02 0.3114 0.6716 1183722 Maybridge3_002174 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C19 compound treatment 0.361 0.0418 3.36 0.358 0.0367 3.34 4.7361 1.0 1717386 Maybridge3_002175 Cc1csc(NC(=O)COCC(=O)O)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C20 compound treatment 0.322 0.00275 0.22 0.331 0.00975 0.89 0.7824 0.8576 1161854 Maybridge3_002176 COc1ccc(Oc2cccc(Cl)c2CNC(=O)CCC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C21 compound treatment 0.325 0.00575 0.46 0.317 -0.00425 -0.39 0.0546 0.0906 1281730 Maybridge3_002177 Cc1oc(cc1C(=O)Nc2ccc(F)cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C22 compound treatment 0.314 -0.00525 -0.42 0.321 -2.5E-4 -0.02 -0.315 -0.744 1668550 Maybridge3_002178 CC1(C)CCc2cc(CN3CCN(Cc4ccccc4)CC3)ccc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C23 mock treatment 0.312 -0.00725 -0.58 0.316 -0.00525 -0.48 -0.7498 -0.9949 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 C24 positive control 0.085 -0.234 -18.86 0.084 -0.237 -21.54 -28.5663 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D01 compound treatment 0.33 0.0107 0.87 0.333 0.0118 1.07 1.3663 0.9946 1252318 Maybridge3_002179 O=S(=O)(Nc1ccc2ccccc2n1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D02 compound treatment 0.327 0.00775 0.62 0.329 0.00775 0.7 0.9387 0.9982 1429002 Maybridge3_002180 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D03 compound treatment 0.322 0.00275 0.22 0.329 0.00775 0.7 0.654 0.8868 2076293 Maybridge3_002181 Cc1cccc(NC(=O)C2CCCCC2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D04 compound treatment 0.323 0.00375 0.3 0.329 0.00775 0.7 0.711 0.9287 1221498 Maybridge3_002182 OC(=O)CCCC(=O)Nc1ccccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D05 compound treatment 0.317 -0.00225 -0.18 0.323 0.00175 0.16 -0.0158 -0.0655 2076294 Maybridge3_002183 CCOC(=O)c1c(C)cccc1NC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D06 compound treatment 0.316 -0.00325 -0.26 0.326 0.00475 0.43 0.1198 0.2376 1560700 Maybridge3_002184 CCc1nc(C)c(CN2CCN(CC2)c3ccc(F)cc3)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D07 compound treatment 0.321 0.00175 0.14 0.329 0.00775 0.7 0.5971 0.8322 1223078 Maybridge3_002185 O=S(=O)(NC1CCCc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D08 compound treatment 0.327 0.00775 0.62 0.33 0.00875 0.79 1.0029 0.9929 1558859 Maybridge3_002186 COc1ccc(SCCC(=O)NCc2ccncc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D09 compound treatment 0.314 -0.00525 -0.42 0.32 -0.00125 -0.11 -0.3792 -0.8662 1473771 Maybridge3_002187 OC1(CCN(Cc2c[nH]nc2c3ccccc3)CC1)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D10 compound treatment 0.315 -0.00425 -0.34 0.329 0.00775 0.7 0.2554 0.3265 1359369 Maybridge3_002188 Cn1nccc1NC(=O)CSCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D11 compound treatment 0.326 0.00675 0.54 0.328 0.00675 0.61 0.8176 0.9982 1313368 Maybridge3_002189 Cc1nc(sc1C(=O)NCc2ccncc2)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D12 compound treatment 0.317 -0.00225 -0.18 0.329 0.00775 0.7 0.3693 0.5084 1381496 Maybridge3_002190 Cc1cc(no1)C(=O)N(CCC#N)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D13 compound treatment 0.387 0.0678 5.46 0.4 0.0788 7.15 8.9123 0.9911 2076295 Maybridge3_002191 O=C/1Nc2ccccc2\C1=C\c3c[nH]nc3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D14 compound treatment 0.316 -0.00325 -0.26 0.322 7.5E-4 0.07 -0.1369 -0.5063 2076296 Maybridge3_002192 Cc1ccc(COc2ncnc3cc(Cl)ccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D15 compound treatment 0.323 0.00375 0.3 0.329 0.00775 0.7 0.711 0.9287 1207876 Maybridge3_002193 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D16 compound treatment 0.354 0.0348 2.8 0.355 0.0338 3.06 4.1449 0.999 2076297 Maybridge3_002194 Clc1ccc2OCC(=Cc2c1)C(=O)Oc3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D17 compound treatment 0.321 0.00175 0.14 0.323 0.00175 0.16 0.212 0.9982 1513373 Maybridge3_002195 OC(CNC(=O)c1ccco1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D18 compound treatment 0.326 0.00675 0.54 0.324 0.00275 0.25 0.5609 0.9377 1485084 Maybridge3_002196 Cc1cc(=O)oc2cc(NS(=O)(=O)c3ccccc3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D19 compound treatment 0.319 -2.5E-4 -0.02 0.32 -0.00125 -0.11 -0.0945 -0.8198 1710996 Maybridge3_002197 OC(CNS(=O)(=O)c1ccc(s1)c2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D20 compound treatment 0.342 0.0227 1.83 0.341 0.0198 1.79 2.5631 0.9999 1187469 Maybridge3_002198 CCOC(=O)C1CCN(CC1)C(=O)c2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D21 compound treatment 0.324 0.00475 0.38 0.327 0.00575 0.52 0.6395 0.9883 1620617 Maybridge3_002199 OC(=O)CC(CC(=O)N1CCOCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D22 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 1279145 Maybridge3_002200 O=C(NC1CCCCNC1=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D23 mock treatment 0.314 -0.00525 -0.42 0.319 -0.00225 -0.2 -0.4434 -0.9443 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 D24 positive control 0.085 -0.234 -18.86 0.086 -0.235 -21.35 -28.4379 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E01 compound treatment 0.327 0.00775 0.62 0.328 0.00675 0.61 0.8745 1.0 1643294 Maybridge3_002201 COc1ccccc1C2CCN(Cc3cccc(c3)C(=O)N4CCC(O)CC4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E02 compound treatment 0.325 0.00575 0.46 0.329 0.00775 0.7 0.8248 0.9794 1368856 Maybridge3_002202 OC(=O)CCCC(=O)Nc1ccc(CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E03 compound treatment 0.314 -0.00525 -0.42 0.318 -0.00325 -0.3 -0.5075 -0.9845 2076298 Maybridge3_002203 OC(CN1CCN(Cc2ccc3OCOc3c2)CC1)Oc4ccc(cc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E04 compound treatment 0.318 -0.00125 -0.1 0.328 0.00675 0.61 0.3621 0.5831 1313338 Maybridge3_002204 CCc1ccnc(NC(=O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E05 compound treatment 0.329 0.00975 0.79 0.33 0.00875 0.79 1.1168 1.0 1541216 Maybridge3_002205 Fc1cc(CNC(=O)c2sc3ccccc3c2Cl)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E06 compound treatment 0.312 -0.00725 -0.58 0.33 0.00875 0.79 0.1488 0.151 2076299 Maybridge3_002206 FC(F)(F)Oc1ccc(cc1)c2cn3cccnc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E07 compound treatment 0.323 0.00375 0.3 0.321 -2.5E-4 -0.02 0.1975 0.6521 1387863 Maybridge3_002207 Clc1ccc2scc(CNS(=O)(=O)c3cccs3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E08 compound treatment 0.307 -0.0123 -0.99 0.32 -0.00125 -0.11 -0.7778 -0.7833 1324463 Maybridge3_002208 COc1cc(OCc2ccccc2)ccc1CN3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E09 compound treatment 0.32 7.5E-4 0.06 0.327 0.00575 0.52 0.4118 0.7837 1647127 Maybridge3_002209 COc1ccc(cc1)n2ncc(C(=O)NCc3sccc3C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E10 compound treatment 0.318 -0.00125 -0.1 0.327 0.00575 0.52 0.2979 0.5604 2076300 Maybridge3_002210 Clc1ccc(c(Cl)c1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E11 compound treatment 0.323 0.00375 0.3 0.326 0.00475 0.43 0.5184 0.9848 1580205 Maybridge3_002211 Cc1cc(C(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E12 compound treatment 0.324 0.00475 0.38 0.33 0.00875 0.79 0.8321 0.9439 2076301 Maybridge3_002212 Cn1ccnc1SCC(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E13 compound treatment 0.335 0.0158 1.27 0.348 0.0267 2.43 2.6138 0.9541 2076302 Maybridge3_002213 O=C(CSc1nccc(n1)c2cccs2)c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E14 compound treatment 0.332 0.0127 1.03 0.339 0.0177 1.61 1.8653 0.9763 2076303 Maybridge3_002214 COc1ccc(OCC(O)CNC(=O)C2=Cc3cc(Cl)ccc3OC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E15 compound treatment 0.333 0.0138 1.11 0.365 0.0437 3.97 3.591 0.871 2076304 Maybridge3_002215 Cc1ccc(cc1)S(=O)(=O)CCSc2ncccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E16 compound treatment 0.319 -2.5E-4 -0.02 0.327 0.00575 0.52 0.3548 0.6793 1715872 Maybridge3_002216 O=C(Nc1ccc(C#N)cc1)C2CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E17 compound treatment 0.318 -0.00125 -0.1 0.322 7.5E-4 0.07 -0.023 -0.1896 1685639 Maybridge3_002217 CCc1ccnc(NC(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E18 compound treatment 0.32 7.5E-4 0.06 0.322 7.5E-4 0.07 0.0908 0.9982 1420319 Maybridge3_002218 Cn1cnc(c1)S(=O)(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E19 compound treatment 0.341 0.0217 1.75 0.34 0.0187 1.7 2.4419 0.9999 2076305 Maybridge3_002219 Cc1csc(NC(=O)CC(C)(C)CC(=O)O)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E20 compound treatment 0.316 -0.00325 -0.26 0.336 0.0147 1.34 0.7617 0.5583 1473463 Maybridge3_002220 COc1ccc(OCC(O)CNS(=O)(=O)c2cc(Cl)sc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E21 compound treatment 0.333 0.0138 1.11 0.34 0.0187 1.7 1.9864 0.9783 1454184 Maybridge3_002221 Cc1oc(cc1C(=O)NCc2ccc3OCOc3c2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E22 compound treatment 0.345 0.0257 2.07 0.328 0.00675 0.61 1.8995 0.8785 1137076 Maybridge3_002222 Fc1ccc(cc1)N2CCN(Cc3c[nH]nc3c4ccc(F)cc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E23 mock treatment 0.315 -0.00425 -0.34 0.315 -0.00625 -0.57 -0.6432 -0.9707 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 E24 positive control 0.088 -0.231 -18.62 0.089 -0.232 -21.08 -28.0746 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F01 compound treatment 0.327 0.00775 0.62 0.325 0.00375 0.34 0.682 0.9594 1516380 Maybridge3_002223 O=S(=O)(Nc1ccc2ccccc2n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F02 compound treatment 0.328 0.00875 0.7 0.333 0.0118 1.07 1.2524 0.9798 1330846 Maybridge3_002224 OC(=O)CCC(=O)N1CCN(CC1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F03 compound treatment 0.326 0.00675 0.54 0.334 0.0127 1.16 1.2027 0.9406 1226869 Maybridge3_002225 Cc1cccc(NC(=O)c2cccnc2Oc3ccccc3)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F04 compound treatment 0.316 -0.00325 -0.26 0.327 0.00575 0.52 0.184 0.3151 1288157 Maybridge3_002226 COc1ccccc1N2CCN(Cc3c[nH]c(n3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F05 compound treatment 0.318 -0.00125 -0.1 0.329 0.00775 0.7 0.4263 0.5998 1631006 Maybridge3_002227 CCc1ccn2cc(nc2c1)c3ccc(s3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F06 compound treatment 0.324 0.00475 0.38 0.336 0.0147 1.34 1.2172 0.8741 1655052 Maybridge3_002228 COc1ccc(OCC2CN=C(O2)c3ccccc3CO)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F07 compound treatment 0.328 0.00875 0.7 0.336 0.0147 1.34 1.445 0.9551 1468699 Maybridge3_002229 CC(C)(CC(=O)O)CC(=O)Nc1ccc2ccccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F08 compound treatment 0.341 0.0217 1.75 0.35 0.0288 2.61 3.0838 0.9812 1135342 Maybridge3_002230 Clc1cc(C(=O)Nc2ccc3ccccc3n2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F09 compound treatment 0.306 -0.0133 -1.07 0.314 -0.00725 -0.66 -1.2198 -0.973 1644086 Maybridge3_002231 C(N1CCc2ccccc2C1)c3c[nH]nc3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F10 compound treatment 0.327 0.00775 0.62 0.331 0.00975 0.89 1.0671 0.9854 1149463 Maybridge3_002232 Cn1nccc1NC(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F11 compound treatment 0.355 0.0357 2.88 0.339 0.0177 1.61 3.1749 0.9624 1623337 Maybridge3_002233 Cc1nc(sc1C(=O)N(Cc2cccs2)Cc3ccccc3)c4cnccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F12 compound treatment 0.36 0.0408 3.28 0.357 0.0357 3.25 4.615 1.0 2076306 Maybridge3_002234 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)N(CCC#N)Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F13 compound treatment 0.326 0.00675 0.54 0.333 0.0118 1.07 1.1385 0.9511 2076307 Maybridge3_002235 O=C(NCCCN1CCOCC1)c2ccccc2NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F14 compound treatment 0.324 0.00475 0.38 0.324 0.00275 0.25 0.447 0.9786 1263314 Maybridge3_002236 Clc1ccc2c(Oc3ccc(NC(=O)c4ccccc4)cn3)ncnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F15 compound treatment 0.326 0.00675 0.54 0.327 0.00575 0.52 0.7534 0.9998 1205269 Maybridge3_002237 COc1cc2CCN(C(C)c2cc1OC)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F16 compound treatment 0.335 0.0158 1.27 0.335 0.0138 1.25 1.7794 1.0 1402282 Maybridge3_002238 CCOC(=O)C1CCN(CC1)C(=O)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F17 compound treatment 0.327 0.00775 0.62 0.327 0.00575 0.52 0.8104 0.9961 1641719 Maybridge3_002239 OC(CNC(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F18 compound treatment 0.332 0.0127 1.03 0.336 0.0147 1.34 1.6727 0.9914 1590616 Maybridge3_002240 Cc1cc(=O)oc2cc(NS(=O)(=O)c3cccs3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F19 compound treatment 0.342 0.0227 1.83 0.341 0.0198 1.79 2.5631 0.9999 2076308 Maybridge3_002241 COc1ccc2nc3CCCCc3nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F20 compound treatment 0.334 0.0147 1.19 0.333 0.0118 1.07 1.5941 0.9986 1251609 Maybridge3_002242 CCOC(=O)C1CCN(CC1)C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F21 compound treatment 0.329 0.00975 0.79 0.33 0.00875 0.79 1.1168 1.0 1543672 Maybridge3_002243 Cn1nc(cc1NC(=O)CC(CC(=O)O)c2ccccc2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F22 compound treatment 0.325 0.00575 0.46 0.326 0.00475 0.43 0.6323 0.9994 1684359 Maybridge3_002244 O=C(NC1CCCCNC1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F23 mock treatment 0.319 -2.5E-4 -0.02 0.324 0.00275 0.25 0.1623 0.648 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 F24 positive control 0.088 -0.231 -18.62 0.088 -0.233 -21.17 -28.1387 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G01 compound treatment 0.331 0.0118 0.95 0.332 0.0107 0.98 1.359 0.9999 1431425 Maybridge3_002245 OC1CCN(CC1)C(=O)c2cccc(CN3CCN(Cc4ccccc4)CC3)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G02 compound treatment 0.325 0.00575 0.46 0.33 0.00875 0.79 0.889 0.967 1570835 Maybridge3_002246 OC(=O)COCC(=O)Nc1ccc(CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G03 compound treatment 0.317 -0.00225 -0.18 0.324 0.00275 0.25 0.0484 0.1569 1224109 Maybridge3_002247 Cc1ccc(NC(=O)c2c(F)cccc2Cl)cc1NS(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G04 compound treatment 0.325 0.00575 0.46 0.333 0.0118 1.07 1.0816 0.9302 1347697 Maybridge3_002248 CCc1ccnc(NC(=O)CCCC(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G05 compound treatment 0.321 0.00175 0.14 0.331 0.00975 0.89 0.7255 0.8095 1126176 Maybridge3_002249 Fc1cc(CNS(=O)(=O)c2ccc(s2)c3ccccn3)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G06 compound treatment 0.323 0.00375 0.3 0.346 0.0248 2.25 1.8021 0.795 2076309 Maybridge3_002250 Cn1c(SCC(=O)N(C2CCCCC2)c3ccccc3)nnc1c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G07 compound treatment 0.316 -0.00325 -0.26 0.327 0.00575 0.52 0.184 0.3151 1358894 Maybridge3_002251 Cc1nnsc1C(=O)NCc2csc3ccc(Cl)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G08 compound treatment 0.328 0.00875 0.7 0.35 0.0288 2.61 2.3436 0.867 1475705 Maybridge3_002252 Cc1oc(cc1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G09 compound treatment 0.315 -0.00425 -0.34 0.321 -2.5E-4 -0.02 -0.258 -0.7523 2076310 Maybridge3_002253 Cc1ccsc1Cn2c(C)ccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G10 compound treatment 0.318 -0.00125 -0.1 0.323 0.00175 0.16 0.0411 0.2188 1486911 Maybridge3_002254 OC(=O)c1cccc(NC(=O)Cc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G11 compound treatment 0.315 -0.00425 -0.34 0.314 -0.00725 -0.66 -0.7073 -0.9536 1730573 Maybridge3_002255 Cc1cc(C(=O)Nc2ccccc2N3CCCCC3)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G12 compound treatment 0.328 0.00875 0.7 0.334 0.0127 1.16 1.3166 0.9717 1198521 Maybridge3_002256 Fc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G13 compound treatment 0.316 -0.00325 -0.26 0.316 -0.00525 -0.48 -0.522 -0.9602 2076311 Maybridge3_002257 Cc1cccc(Cn2c(=O)oc3ccc(C)cc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G14 compound treatment 0.318 -0.00125 -0.1 0.327 0.00575 0.52 0.2979 0.5604 1593809 Maybridge3_002258 COc1ccc(OCC(O)CNC(=O)C2CCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G15 compound treatment 0.326 0.00675 0.54 0.324 0.00275 0.25 0.5609 0.9377 1177532 Maybridge3_002259 Fc1ccc(cc1)S(=O)(=O)CCn2c(=O)oc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G16 compound treatment 0.334 0.0147 1.19 0.326 0.00475 0.43 1.1448 0.9059 1706575 Maybridge3_002260 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G17 compound treatment 0.341 0.0217 1.75 0.336 0.0147 1.34 2.1852 0.9912 2076312 Maybridge3_002261 Cc1cc(ccc1Cl)C(=O)CSc2nccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G18 compound treatment 0.323 0.00375 0.3 0.332 0.0107 0.98 0.9035 0.8845 2076313 Maybridge3_002262 OC(=O)CCCC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G19 compound treatment 0.35 0.0308 2.48 0.35 0.0288 2.61 3.5963 0.9997 2076314 Maybridge3_002263 Cc1csc(NC(=O)CCCC(=O)O)c1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G20 compound treatment 0.327 0.00775 0.62 0.328 0.00675 0.61 0.8745 1.0 1529442 Maybridge3_002264 COc1ccc(OCC(O)CNS(=O)(=O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G21 compound treatment 0.319 -2.5E-4 -0.02 0.323 0.00175 0.16 0.0981 0.6126 1540060 Maybridge3_002265 CCOC(=O)C1CCN(Cc2c[nH]c3ccccc23)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G22 compound treatment 0.309 -0.0103 -0.83 0.313 -0.00825 -0.75 -1.1132 -0.9988 1580458 Maybridge3_002266 Fc1ccc(cc1)C(=O)C2CCN(Cc3c[nH]nc3c4ccc(F)cc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G23 mock treatment 0.317 -0.00225 -0.18 0.322 7.5E-4 0.07 -0.08 -0.4132 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 G24 positive control 0.09 -0.229 -18.46 0.088 -0.233 -21.17 -28.0249 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H01 compound treatment 0.329 0.00975 0.79 0.333 0.0118 1.07 1.3093 0.9886 1141088 Maybridge3_002267 O=C(Nc1ccc2ccccc2n1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H02 compound treatment 0.326 0.00675 0.54 0.33 0.00875 0.79 0.946 0.9829 1433038 Maybridge3_002268 OC(=O)CCCC(=O)N1CCN(CC1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H03 compound treatment 0.326 0.00675 0.54 0.331 0.00975 0.89 1.0102 0.9726 1490659 Maybridge3_002269 Cc1cccc(NC(=O)c2ccccc2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H04 compound treatment 0.321 0.00175 0.14 0.327 0.00575 0.52 0.4687 0.867 2076315 Maybridge3_002270 FC(F)(F)c1ccnc(c1)N2CCN(Cc3c[nH]c(n3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H05 compound treatment 0.324 0.00475 0.38 0.335 0.0138 1.25 1.153 0.8833 1400360 Maybridge3_002271 CCc1ccn2cc(Nc3ccccc3Cl)nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H06 compound treatment 0.323 0.00375 0.3 0.333 0.0118 1.07 0.9677 0.873 1403231 Maybridge3_002272 OC(=O)C1=C(CCCC1)C(=O)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H07 compound treatment 0.318 -0.00125 -0.1 0.327 0.00575 0.52 0.2979 0.5604 1373704 Maybridge3_002273 OC(=O)CC(CC(=O)Oc1ccccc1N2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H08 compound treatment 0.319 -2.5E-4 -0.02 0.326 0.00475 0.43 0.2906 0.6734 1468822 Maybridge3_002274 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc4ccccc4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H09 compound treatment 0.307 -0.0123 -0.99 0.307 -0.0143 -1.29 -1.6122 -0.9911 2076316 Maybridge3_002275 COc1ccc(cc1)c2n[nH]cc2CN3CCN(CC3)c4ncc(cc4Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H10 compound treatment 0.322 0.00275 0.22 0.325 0.00375 0.34 0.3973 0.9783 1568822 Maybridge3_002276 Cn1nccc1NC(=O)CC(CC(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H11 compound treatment 0.325 0.00575 0.46 0.324 0.00275 0.25 0.5039 0.958 1163929 Maybridge3_002277 CN1CCN(CC1)C(=O)c2sc(nc2C)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H12 compound treatment 0.312 -0.00725 -0.58 0.325 0.00375 0.34 -0.1721 -0.2547 1620795 Maybridge3_002278 Clc1ccc(cc1)C(=O)N(CCC#N)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H13 compound treatment 0.331 0.0118 0.95 0.335 0.0138 1.25 1.5516 0.9907 1711589 Maybridge3_002279 CCCc1cnc(Oc2ncnc3cc(Cl)ccc23)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H14 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 2076317 Maybridge3_002280 OC(=O)C1CCCC=C1C(=O)Nc2ccc(CC#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H15 compound treatment 0.32 7.5E-4 0.06 0.321 -2.5E-4 -0.02 0.0267 0.4132 2076318 Maybridge3_002281 Fc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H16 compound treatment 0.304 -0.0153 -1.23 0.32 -0.00125 -0.11 -0.9486 -0.7692 2076319 Maybridge3_002282 CCc1nc(C)c(CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H17 compound treatment 0.328 0.00875 0.7 0.323 0.00175 0.16 0.6106 0.8453 1564036 Maybridge3_002283 Cc1ccc(cc1)C(=O)NCC(O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H18 compound treatment 0.326 0.00675 0.54 0.325 0.00375 0.34 0.625 0.9746 1553721 Maybridge3_002284 Cc1cc(=O)oc2cc(NS(=O)(=O)c3ccc4OCCc4c3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H19 compound treatment 0.33 0.0107 0.87 0.323 0.00175 0.16 0.7244 0.8231 2076320 Maybridge3_002285 OC(=O)c1ccc(Oc2ccccc2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H20 compound treatment 0.364 0.0447 3.6 0.357 0.0357 3.25 4.8427 0.9986 1475536 Maybridge3_002286 CCOC(=O)C1CCN(CC1)C(=O)c2sc(nc2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H21 compound treatment 0.336 0.0168 1.35 0.333 0.0118 1.07 1.7079 0.9932 1500661 Maybridge3_002287 Cc1ccc2cc(NC(=O)CC(CC(=O)O)c3ccccc3)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H22 compound treatment 0.333 0.0138 1.11 0.334 0.0127 1.16 1.6013 0.9998 2076321 Maybridge3_002288 Cc1nc(ccc1C(=O)NC2CCCCNC2=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H23 mock treatment 0.321 0.00175 0.14 0.324 0.00275 0.25 0.2762 0.9634 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 H24 positive control 0.089 -0.23 -18.54 0.091 -0.23 -20.9 -27.8892 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I01 compound treatment 0.317 -0.00225 -0.18 0.324 0.00275 0.25 0.0484 0.1569 1639674 Maybridge3_002289 COc1ccccc1C2CCN(Cc3c[nH]c4ccccc34)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I02 compound treatment 0.327 0.00775 0.62 0.334 0.0127 1.16 1.2597 0.958 1627756 Maybridge3_002290 OC(=O)CCC(=O)Nc1ccc(CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I03 compound treatment 0.329 0.00975 0.79 0.338 0.0168 1.52 1.6303 0.9527 2076322 Maybridge3_002291 Cc1nnsc1C(=O)Nc2nc(c(C)s2)c3ccc(C)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I04 compound treatment 0.321 0.00175 0.14 0.327 0.00575 0.52 0.4687 0.867 1123023 Maybridge3_002292 CCc1ccnc(NC(=O)CC2(CC(=O)O)CCCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I05 compound treatment 0.318 -0.00125 -0.1 0.323 0.00175 0.16 0.0411 0.2188 2076323 Maybridge3_002293 O=S(=O)(Nc1ccc2OCCOc2c1)c3ccc(s3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I06 compound treatment 0.331 0.0118 0.95 0.329 0.00775 0.7 1.1665 0.9893 1249886 Maybridge3_002294 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3cc(C)on3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I07 compound treatment 0.322 0.00275 0.22 0.329 0.00775 0.7 0.654 0.8868 1389401 Maybridge3_002295 Clc1ccc2scc(CNC(=O)c3ccno3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I08 compound treatment 0.341 0.0217 1.75 0.331 0.00975 0.89 1.8643 0.95 1700532 Maybridge3_002296 COc1ccccc1N2CCN(CC2)C(=O)c3cc(oc3C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I09 compound treatment 0.327 0.00775 0.62 0.335 0.0138 1.25 1.3238 0.9487 1456793 Maybridge3_002297 Cc1onc(c1CN2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I10 compound treatment 0.327 0.00775 0.62 0.331 0.00975 0.89 1.0671 0.9854 2076324 Maybridge3_002298 CC(C)(CC(=O)O)CC(=O)Nc1cccc(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I11 compound treatment 0.318 -0.00125 -0.1 0.32 -0.00125 -0.11 -0.1514 -0.9982 1432360 Maybridge3_002299 O=C(Nc1ccccc1c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I12 compound treatment 0.316 -0.00325 -0.26 0.315 -0.00625 -0.57 -0.5862 -0.9383 2076325 Maybridge3_002300 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSC4=NCCS4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I13 compound treatment 0.338 0.0187 1.51 0.338 0.0168 1.52 2.1427 1.0 1415441 Maybridge3_002301 Cc1ccc2oc(=O)n(CC(=O)N3CCOCC3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I14 compound treatment 0.329 0.00975 0.79 0.331 0.00975 0.89 1.181 0.9982 1705043 Maybridge3_002302 CC(C)(CC(=O)O)CC(=O)Nc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I15 compound treatment 0.32 7.5E-4 0.06 0.309 -0.0123 -1.11 -0.7436 -0.6677 1187774 Maybridge3_002303 Cc1ccc(cc1)S(=O)(=O)CCn2c(=O)oc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I16 compound treatment 0.311 -0.00825 -0.66 0.317 -0.00425 -0.39 -0.7425 -0.9666 1329577 Maybridge3_002304 COc1cc(OCc2ccccc2)ccc1CN3CCN(C)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I17 compound treatment 0.29 -0.0293 -2.36 0.292 -0.0293 -2.66 -3.5429 -0.9982 1621859 Maybridge3_002305 OC(=O)Cc1ccc(s1)C(=O)CSc2nccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I18 compound treatment 0.345 0.0257 2.07 0.349 0.0278 2.52 3.2474 0.9953 2076326 Maybridge3_002306 OC(=O)CC(CC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I19 compound treatment 0.344 0.0248 1.99 0.345 0.0238 2.16 2.9337 0.9992 2076327 Maybridge3_002307 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I20 compound treatment 0.332 0.0127 1.03 0.337 0.0158 1.43 1.7369 0.9868 1154517 Maybridge3_002308 Cc1cccc(NC(=O)c2cccs2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I21 compound treatment 0.365 0.0457 3.68 0.368 0.0468 4.24 5.6057 0.9975 1384110 Maybridge3_002309 COC(=O)C1=C(C)NC2=C(C1c3c[nH]cn3)C(=O)CC(C)(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I22 compound treatment 0.332 0.0127 1.03 0.338 0.0168 1.52 1.8011 0.9817 1686610 Maybridge3_002310 C(N1CCN(CC1)c2ccccn2)c3c[nH]nc3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I23 mock treatment 0.329 0.00975 0.79 0.325 0.00375 0.34 0.7959 0.93 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 I24 positive control 0.09 -0.229 -18.46 0.089 -0.232 -21.08 -27.9607 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J01 compound treatment 0.329 0.00975 0.79 0.333 0.0118 1.07 1.3093 0.9886 1594550 Maybridge3_002311 O=C(Nc1ccc2ccccc2n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J02 compound treatment 0.332 0.0127 1.03 0.339 0.0177 1.61 1.8653 0.9763 1274925 Maybridge3_002312 COc1ccc(cc1)n2ncc(C(=O)N3CCN(C)CC3)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J03 compound treatment 0.325 0.00575 0.46 0.326 0.00475 0.43 0.6323 0.9994 1266203 Maybridge3_002313 Cc1cccc(NC(=O)c2ccco2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J04 compound treatment 0.32 7.5E-4 0.06 0.324 0.00275 0.25 0.2192 0.8536 1641975 Maybridge3_002314 Fc1ccc(cc1)N2CCN(Cc3c[nH]c(n3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J05 compound treatment 0.329 0.00975 0.79 0.339 0.0177 1.61 1.6945 0.9454 1332395 Maybridge3_002315 CCc1ccn2cc(nc2c1)c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J06 compound treatment 0.327 0.00775 0.62 0.335 0.0138 1.25 1.3238 0.9487 2076328 Maybridge3_002316 OC(=O)C1=C(CCCC1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J07 compound treatment 0.32 7.5E-4 0.06 0.334 0.0127 1.16 0.8611 0.743 1409549 Maybridge3_002317 O=C(Oc1ccccc1N2CCCCC2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J08 compound treatment 0.314 -0.00525 -0.42 0.326 0.00475 0.43 0.0059 0.0098 1254912 Maybridge3_002318 O=C(Nc1ccc2ccccc2n1)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J09 compound treatment 0.328 0.00875 0.7 0.335 0.0138 1.25 1.3808 0.9634 2076329 Maybridge3_002319 COc1ccc(cc1)c2n[nH]cc2CN3CCN(CC3)c4cc(ccn4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J10 compound treatment 0.336 0.0168 1.35 0.339 0.0177 1.61 2.093 0.9961 1719999 Maybridge3_002320 OC(=O)C1=C(SCCS1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J11 compound treatment 0.328 0.00875 0.7 0.332 0.0107 0.98 1.1882 0.9872 2076330 Maybridge3_002321 Cc1c(cnn1c2ccc(F)cc2)C(=O)NCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J12 compound treatment 0.322 0.00275 0.22 0.328 0.00675 0.61 0.5898 0.9054 1360075 Maybridge3_002322 Cc1cc(no1)C(=O)N(CCC#N)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J13 compound treatment 0.347 0.0278 2.23 0.35 0.0288 2.61 3.4254 0.997 1477492 Maybridge3_002323 CCCc1cnc(nc1)N2CCN(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J14 compound treatment 0.321 0.00175 0.14 0.327 0.00575 0.52 0.4687 0.867 1449555 Maybridge3_002324 O=C(Nc1ccccc1)Oc2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J15 compound treatment 0.318 -0.00125 -0.1 0.321 -2.5E-4 -0.02 -0.0872 -0.8453 1585268 Maybridge3_002325 O=S(=O)(NC1CCCc2ccccc12)c3cccc4nonc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J16 compound treatment 0.32 7.5E-4 0.06 0.325 0.00375 0.34 0.2834 0.8198 2076331 Maybridge3_002326 CCc1nc(C)c(CN2CCN(CC2)c3cc(ccn3)C(F)(F)F)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J17 compound treatment 0.323 0.00375 0.3 0.316 -0.00525 -0.48 -0.1234 -0.2188 1303123 Maybridge3_002327 Cc1cc(sc1C(=O)NCC(O)c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J18 compound treatment 0.332 0.0127 1.03 0.332 0.0107 0.98 1.416 0.9997 1276354 Maybridge3_002328 Cc1ccc2oc(=O)n(CCC#N)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J19 compound treatment 0.332 0.0127 1.03 0.328 0.00675 0.61 1.1592 0.9696 1521483 Maybridge3_002329 CS(=O)(=O)Nc1ccc2OCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J20 compound treatment 0.336 0.0168 1.35 0.332 0.0107 0.98 1.6437 0.9874 1607287 Maybridge3_002330 OC(=O)C1CCN(CC1)C(=O)c2csc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J21 compound treatment 0.332 0.0127 1.03 0.332 0.0107 0.98 1.416 0.9997 1245149 Maybridge3_002331 CC(=O)Nc1ccc(NC(=O)CC(CC(=O)O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J22 compound treatment 0.333 0.0138 1.11 0.327 0.00575 0.52 1.152 0.9411 1739685 Maybridge3_002332 Cc1nnsc1C(=O)NC2CCCCNC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J23 mock treatment 0.322 0.00275 0.22 0.319 -0.00225 -0.2 0.0122 0.0404 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 J24 positive control 0.09 -0.229 -18.46 0.09 -0.231 -20.99 -27.8965 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K01 compound treatment 0.324 0.00475 0.38 0.327 0.00575 0.52 0.6395 0.9883 1243532 Maybridge3_002333 CCOC(=O)C1CCN(CC1)c2ccccc2CN3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K02 compound treatment 0.328 0.00875 0.7 0.333 0.0118 1.07 1.2524 0.9798 1353584 Maybridge3_002334 OC(=O)CC1(CC(=O)Nc2ccc(CC#N)cc2)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K03 compound treatment 0.329 0.00975 0.79 0.327 0.00575 0.52 0.9242 0.9803 2076332 Maybridge3_002335 Cc1nnsc1C(=O)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K04 compound treatment 0.325 0.00575 0.46 0.332 0.0107 0.98 1.0174 0.942 2076333 Maybridge3_002336 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K05 compound treatment 0.326 0.00675 0.54 0.337 0.0158 1.43 1.3953 0.9122 1407188 Maybridge3_002337 CCS(=O)(=O)c1ccc2oc(=O)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K06 compound treatment 0.329 0.00975 0.79 0.344 0.0227 2.07 2.0154 0.9122 1478031 Maybridge3_002338 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K07 compound treatment 0.316 -0.00325 -0.26 0.329 0.00775 0.7 0.3124 0.4162 1222728 Maybridge3_002339 OC(=O)c1cccc(NC(=O)c2ccco2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K08 compound treatment 0.324 0.00475 0.38 0.322 7.5E-4 0.07 0.3186 0.8201 1610240 Maybridge3_002340 O=C(Nc1ccc2OCCOc2c1)c3cccnc3Sc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K09 compound treatment 0.324 0.00475 0.38 0.325 0.00375 0.34 0.5112 0.9983 1508771 Maybridge3_002341 Cc1onc(c1CN2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K10 compound treatment 0.324 0.00475 0.38 0.329 0.00775 0.7 0.7679 0.959 2076334 Maybridge3_002342 OC(=O)CSCC(=O)Nc1cccc(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K11 compound treatment 0.329 0.00975 0.79 0.328 0.00675 0.61 0.9884 0.9925 1240646 Maybridge3_002343 OC(=O)CCCC(=O)Nc1ccccc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K12 compound treatment 0.323 0.00375 0.3 0.332 0.0107 0.98 0.9035 0.8845 1478581 Maybridge3_002344 OC(=O)CC1(CC(=O)Nc2cccc(c2)C(=O)O)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K13 compound treatment 0.319 -2.5E-4 -0.02 0.323 0.00175 0.16 0.0981 0.6126 1400750 Maybridge3_002345 Cc1ccc2oc(=O)n(CC(=O)C(C)(C)C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K14 compound treatment 0.323 0.00375 0.3 0.33 0.00875 0.79 0.7751 0.9122 1593396 Maybridge3_002346 OC(=O)CCCC(=O)Nc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K15 compound treatment 0.331 0.0118 0.95 0.327 0.00575 0.52 1.0381 0.9607 1708789 Maybridge3_002347 CCc1ccccc1Cn2c(=O)oc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K16 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 1634242 Maybridge3_002348 COc1cc(OCc2ccccc2)ccc1CN3CCN(CC3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K17 compound treatment 0.331 0.0118 0.95 0.322 7.5E-4 0.07 0.7172 0.756 2076335 Maybridge3_002349 Clc1cccc(NC(=O)CSc2nccc(n2)c3cccs3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K18 compound treatment 0.33 0.0107 0.87 0.333 0.0118 1.07 1.3663 0.9946 2076336 Maybridge3_002350 OC(=O)CCC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K19 compound treatment 0.331 0.0118 0.95 0.333 0.0118 1.07 1.4232 0.9982 1703059 Maybridge3_002351 Cn1cnc(c1)S(=O)(=O)NCc2c(Cl)cccc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K20 compound treatment 0.308 -0.0113 -0.91 0.32 -0.00125 -0.11 -0.7208 -0.7895 2076337 Maybridge3_002352 Fc1ccc(cc1)S(=O)(=O)CCSCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K21 compound treatment 0.34 0.0208 1.67 0.344 0.0227 2.07 2.6417 0.9945 1534053 Maybridge3_002353 COC(=O)C1=C(C)NC2=C(C1c3sccc3C)C(=O)CC(C)(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K22 compound treatment 0.326 0.00675 0.54 0.331 0.00975 0.89 1.0102 0.9726 1350896 Maybridge3_002354 Cc1cc(=O)[nH]c2cc(nn12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K23 mock treatment 0.321 0.00175 0.14 0.33 0.00875 0.79 0.6613 0.8198 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 K24 positive control 0.092 -0.227 -18.3 0.093 -0.228 -20.72 -27.59 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L01 compound treatment 0.337 0.0177 1.43 0.34 0.0187 1.7 2.2142 0.9962 2076338 Maybridge3_002355 Cc1nc(ccc1C(=O)Nc2ccc3ccccc3n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L02 compound treatment 0.333 0.0138 1.11 0.336 0.0147 1.34 1.7297 0.9955 1119993 Maybridge3_002356 COc1ccc(cc1)n2ncc(C(=O)N3CCCCC3)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L03 compound treatment 0.323 0.00375 0.3 0.329 0.00775 0.7 0.711 0.9287 1417072 Maybridge3_002357 Cc1nnsc1c2nc3cccc(C)c3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L04 compound treatment 0.317 -0.00225 -0.18 0.324 0.00275 0.25 0.0484 0.1569 1577207 Maybridge3_002358 C(N1CCN(Cc2ccccc2)CC1)c3c[nH]c(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L05 compound treatment 0.33 0.0107 0.87 0.334 0.0127 1.16 1.4305 0.9898 2076339 Maybridge3_002359 CCc1ccnc(NS(=O)(=O)c2ccc3OCCCOc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L06 compound treatment 0.328 0.00875 0.7 0.332 0.0107 0.98 1.1882 0.9872 2076340 Maybridge3_002360 COC(=O)c1ccccc1NC(=O)C2=CCCCC2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L07 compound treatment 0.33 0.0107 0.87 0.327 0.00575 0.52 0.9812 0.9707 1564633 Maybridge3_002361 Cc1nnsc1C(=O)Oc2ccccc2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L08 compound treatment 0.321 0.00175 0.14 0.32 -0.00125 -0.11 0.0194 0.1073 1529955 Maybridge3_002362 COc1ccccc1CC(=O)Nc2ccc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L09 compound treatment 0.33 0.0107 0.87 0.329 0.00775 0.7 1.1095 0.9947 1276420 Maybridge3_002363 COc1ccc(OCC(O)CNS(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L10 compound treatment 0.332 0.0127 1.03 0.324 0.00275 0.25 0.9025 0.8541 1460829 Maybridge3_002364 Cc1noc(C)c1S(=O)(=O)N(CCC#N)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L11 compound treatment 0.331 0.0118 0.95 0.323 0.00175 0.16 0.7814 0.8144 1555306 Maybridge3_002365 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L12 compound treatment 0.325 0.00575 0.46 0.326 0.00475 0.43 0.6323 0.9994 1207042 Maybridge3_002366 O=C(N(CCC#N)Cc1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L13 compound treatment 0.337 0.0177 1.43 0.329 0.00775 0.7 1.5081 0.9467 2076341 Maybridge3_002367 OC(=O)CSCC(=O)N1CCN(CC1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L14 compound treatment 0.33 0.0107 0.87 0.323 0.00175 0.16 0.7244 0.8231 2076342 Maybridge3_002368 Cc1ccc(NC(=O)Oc2ccccc2N3CCOCC3)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L15 compound treatment 0.332 0.0127 1.03 0.335 0.0138 1.25 1.6085 0.9953 2076343 Maybridge3_002369 Cc1noc(C)c1S(=O)(=O)NC2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L16 compound treatment 0.317 -0.00225 -0.18 0.313 -0.00825 -0.75 -0.6576 -0.8536 1245697 Maybridge3_002370 Cc1[nH]c2ccccc2c1CN3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L17 compound treatment 0.329 0.00975 0.79 0.335 0.0138 1.25 1.4377 0.975 1235577 Maybridge3_002371 Cc1onc(c1C(=O)NCC(O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L18 compound treatment 0.329 0.00975 0.79 0.331 0.00975 0.89 1.181 0.9982 1370152 Maybridge3_002372 Cn1cnc(c1)S(=O)(=O)Nc2ccccc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L19 compound treatment 0.333 0.0138 1.11 0.335 0.0138 1.25 1.6655 0.9982 1300179 Maybridge3_002373 Cc1ccc(NC(=O)CC(CC(=O)O)c2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L20 compound treatment 0.36 0.0408 3.28 0.351 0.0297 2.7 4.2298 0.9953 1285469 Maybridge3_002374 CCOC(=O)C1CCN(CC1)C(=O)c2cncc(c2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L21 compound treatment 0.333 0.0138 1.11 0.33 0.00875 0.79 1.3446 0.9867 1283721 Maybridge3_002375 COC(=O)c1cscc1NC(=O)CC(CC(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L22 compound treatment 0.332 0.0127 1.03 0.333 0.0118 1.07 1.4802 0.9998 1147533 Maybridge3_002376 O=C1NCCCCC1NS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L23 mock treatment 0.326 0.00675 0.54 0.324 0.00275 0.25 0.5609 0.9377 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 L24 positive control 0.092 -0.227 -18.3 0.092 -0.229 -20.81 -27.6542 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M01 compound treatment 0.341 0.0217 1.75 0.341 0.0198 1.79 2.5061 0.9999 1201169 Maybridge3_002377 Cc1ccc(C)n1c2ccc(cc2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M02 compound treatment 0.325 0.00575 0.46 0.329 0.00775 0.7 0.8248 0.9794 2076344 Maybridge3_002378 Cn1nc(c(c1NC(=O)c2cccnc2)c3ccccc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M03 compound treatment 0.322 0.00275 0.22 0.324 0.00275 0.25 0.3331 0.9982 1613085 Maybridge3_002379 O=C(Nc1ccc2OCCOc2c1)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M04 compound treatment 0.326 0.00675 0.54 0.329 0.00775 0.7 0.8818 0.9919 1468785 Maybridge3_002380 CNc1nnc(s1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M05 compound treatment 0.329 0.00975 0.79 0.341 0.0198 1.79 1.8228 0.9314 1155852 Maybridge3_002381 Cc1ccc2oc(=O)n(CC(=O)c3ccc(F)cc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M06 compound treatment 0.324 0.00475 0.38 0.331 0.00975 0.89 0.8963 0.9296 1184241 Maybridge3_002382 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3snnc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M07 compound treatment 0.318 -0.00125 -0.1 0.326 0.00475 0.43 0.2337 0.5278 1633649 Maybridge3_002383 O=C(CSc1ccccc1)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M08 compound treatment 0.365 0.0457 3.68 0.374 0.0527 4.79 5.9908 0.9916 1283767 Maybridge3_002384 CC(C)(C)c1ccc(cc1)C2=NC(=O)C(CC(=O)O)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M09 compound treatment 0.337 0.0177 1.43 0.339 0.0177 1.61 2.15 0.9982 2076345 Maybridge3_002385 Cc1cc(C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M10 compound treatment 0.306 -0.0133 -1.07 0.308 -0.0133 -1.2 -1.6049 -0.9982 1505676 Maybridge3_002386 Clc1cncc(Cl)c1N2CCCN(CC2)S(=O)(=O)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M11 compound treatment 0.306 -0.0133 -1.07 0.316 -0.00525 -0.48 -1.0914 -0.934 2076346 Maybridge3_002387 O=C(CSc1nccc(n1)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M12 compound treatment 0.326 0.00675 0.54 0.327 0.00575 0.52 0.7534 0.9998 1668895 Maybridge3_002388 OC(=O)c1cccc(NC(=O)c2ccccc2C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M13 compound treatment 0.324 0.00475 0.38 0.322 7.5E-4 0.07 0.3186 0.8201 1168510 Maybridge3_002389 CC(C)(CC(=O)O)CC(=O)N1CCCN(CC1)c2c(Cl)cncc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M14 compound treatment 0.325 0.00575 0.46 0.328 0.00675 0.61 0.7607 0.9905 1433856 Maybridge3_002390 OC(=O)COCC(=O)Nc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M15 compound treatment 0.321 0.00175 0.14 0.327 0.00575 0.52 0.4687 0.867 1180787 Maybridge3_002391 OC(=O)CSCC(=O)Nc1ccc2COC(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M16 compound treatment 0.314 -0.00525 -0.42 0.323 0.00175 0.16 -0.1866 -0.4132 2076347 Maybridge3_002392 FC(F)(F)Oc1ccc(cc1)C(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M17 compound treatment 0.318 -0.00125 -0.1 0.321 -2.5E-4 -0.02 -0.0872 -0.8453 1576503 Maybridge3_002393 O=C(CSc1nccc(n1)c2cccs2)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M18 compound treatment 0.324 0.00475 0.38 0.334 0.0127 1.16 1.0888 0.8933 1614183 Maybridge3_002394 O=C1CCC(=O)N1c2ccc(CC#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M19 compound treatment 0.352 0.0328 2.64 0.351 0.0297 2.7 3.7743 0.9999 1409230 Maybridge3_002395 Cc1oc(cc1C(=O)Nc2ccc(cc2)N3CCOCC3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M20 compound treatment 0.322 0.00275 0.22 0.325 0.00375 0.34 0.3973 0.9783 1117665 Maybridge3_002396 CCc1ccnc(NS(=O)(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M21 compound treatment 0.342 0.0227 1.83 0.341 0.0198 1.79 2.5631 0.9999 1654927 Maybridge3_002397 COC(=O)C1=C(C)NC2=C(C1c3ccco3)C(=O)CC(C2)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M22 compound treatment 0.325 0.00575 0.46 0.333 0.0118 1.07 1.0816 0.9302 1245561 Maybridge3_002398 Oc1ccc2occ(C(=O)c3ccco3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M23 mock treatment 0.321 0.00175 0.14 0.321 -2.5E-4 -0.02 0.0836 0.5857 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 M24 positive control 0.093 -0.226 -18.22 0.093 -0.228 -20.72 -27.5331 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N01 compound treatment 0.33 0.0107 0.87 0.332 0.0107 0.98 1.3021 0.9982 2076348 Maybridge3_002399 OC(=O)c1ccccc1S(=O)(=O)Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N02 compound treatment 0.332 0.0127 1.03 0.334 0.0127 1.16 1.5444 0.9982 1694998 Maybridge3_002400 OC(=O)CSCC(=O)Nc1ccccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N03 compound treatment 0.331 0.0118 0.95 0.331 0.00975 0.89 1.2949 0.9994 1299933 Maybridge3_002401 Cc1cccc2nc(oc(=O)c12)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N04 compound treatment 0.321 0.00175 0.14 0.321 -2.5E-4 -0.02 0.0836 0.5857 1692071 Maybridge3_002402 CCOc1ccccc1N2CCN(Cc3c[nH]c(n3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N05 compound treatment 0.328 0.00875 0.7 0.327 0.00575 0.52 0.8673 0.9891 1459009 Maybridge3_002403 CCc1ccnc(NS(=O)(=O)c2ccc3OCCc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N06 compound treatment 0.332 0.0127 1.03 0.329 0.00775 0.7 1.2234 0.983 2076349 Maybridge3_002404 OC(=O)C1CCCC=C1C(=O)Nc2ccccc2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N07 compound treatment 0.319 -2.5E-4 -0.02 0.325 0.00375 0.34 0.2265 0.6641 1255298 Maybridge3_002405 CN1CCN(Cc2c[nH]nc2c3ccccc3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N08 compound treatment 0.34 0.0208 1.67 0.347 0.0257 2.34 2.8343 0.9865 1431087 Maybridge3_002406 COc1ccc(cc1OC)C(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N09 compound treatment 0.345 0.0257 2.07 0.343 0.0217 1.97 2.8623 0.9997 1382278 Maybridge3_002407 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N10 compound treatment 0.329 0.00975 0.79 0.329 0.00775 0.7 1.0526 0.9985 1442660 Maybridge3_002408 O=S(=O)(N(CCC#N)Cc1ccccc1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N11 compound treatment 0.326 0.00675 0.54 0.327 0.00575 0.52 0.7534 0.9998 1461744 Maybridge3_002409 OC(=O)CCCC(=O)N1CCN(CC1)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N12 compound treatment 0.335 0.0158 1.27 0.339 0.0177 1.61 2.0361 0.993 1458429 Maybridge3_002410 COc1cc2CCN(C(C)c2cc1OC)C(=O)CC(C)(C)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N13 compound treatment 0.334 0.0147 1.19 0.331 0.00975 0.89 1.4657 0.9895 1156091 Maybridge3_002411 OC(=O)CSCC(=O)N1CCC2(CC1)OCCO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N14 compound treatment 0.333 0.0138 1.11 0.339 0.0177 1.61 1.9222 0.9832 1386307 Maybridge3_002412 O=C(Oc1ccccc1N2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N15 compound treatment 0.324 0.00475 0.38 0.326 0.00475 0.43 0.5753 0.9982 1474229 Maybridge3_002413 Cc1noc(C)c1S(=O)(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N16 compound treatment 0.351 0.0318 2.56 0.349 0.0278 2.52 3.589 1.0 1263162 Maybridge3_002414 Cc1nc(sc1C(=O)Oc2ccccc2N3CCOCC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N17 compound treatment 0.325 0.00575 0.46 0.327 0.00575 0.52 0.6965 0.9982 1198539 Maybridge3_002415 OC(CNS(=O)(=O)c1cc(Cl)sc1Cl)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N18 compound treatment 0.326 0.00675 0.54 0.332 0.0107 0.98 1.0743 0.9618 2076350 Maybridge3_002416 O=S(=O)(Nc1ccc2ccccc2n1)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N19 compound treatment 0.331 0.0118 0.95 0.332 0.0107 0.98 1.359 0.9999 1403212 Maybridge3_002417 OC(=O)CC(CC(=O)Nc1ccc(cc1)N2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N20 compound treatment 0.327 0.00775 0.62 0.33 0.00875 0.79 1.0029 0.9929 1562445 Maybridge3_002418 OC(=O)C1CCN(CC1)C(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N21 compound treatment 0.34 0.0208 1.67 0.34 0.0187 1.7 2.385 1.0 1225906 Maybridge3_002419 OC(=O)CC(CC(=O)Nc1ccc2ccccc2n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N22 compound treatment 0.329 0.00975 0.79 0.327 0.00575 0.52 0.9242 0.9803 1271552 Maybridge3_002420 O=C1NCCCCC1NS(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N23 mock treatment 0.324 0.00475 0.38 0.324 0.00275 0.25 0.447 0.9786 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 N24 positive control 0.091 -0.228 -18.38 0.099 -0.222 -20.17 -27.2619 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O01 compound treatment 0.34 0.0208 1.67 0.345 0.0238 2.16 2.7059 0.9921 1014845 Maybridge3_002421 NS(=O)(=O)c1ccc(cc1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O02 compound treatment 0.334 0.0147 1.19 0.339 0.0177 1.61 1.9792 0.9887 2076351 Maybridge3_002422 Cn1nc(c(c1NC(=O)c2ccco2)c3ccccc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O03 compound treatment 0.332 0.0127 1.03 0.335 0.0138 1.25 1.6085 0.9953 1646482 Maybridge3_002423 Cc1noc(C)c1C(=O)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O04 compound treatment 0.337 0.0177 1.43 0.336 0.0147 1.34 1.9574 0.9995 2076352 Maybridge3_002424 Fc1ccc(cc1)c2cn3cccnc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O05 compound treatment 0.342 0.0227 1.83 0.341 0.0198 1.79 2.5631 0.9999 1636345 Maybridge3_002425 COc1ccc(cc1)C(=O)Cn2c(=O)oc3ccc(C)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O06 compound treatment 0.338 0.0187 1.51 0.34 0.0187 1.7 2.2711 0.9982 1159987 Maybridge3_002426 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3c(C)noc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O07 compound treatment 0.329 0.00975 0.79 0.332 0.0107 0.98 1.2452 0.9942 1331220 Maybridge3_002427 CN(C(=O)c1ccco1)c2ccc(Cl)cc2C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O08 compound treatment 0.446 0.127 10.21 0.442 0.121 10.96 14.9676 0.9994 2076353 Maybridge3_002428 OC(=O)CC1SC(=NC1=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O09 compound treatment 0.333 0.0138 1.11 0.336 0.0147 1.34 1.7297 0.9955 1459703 Maybridge3_002429 Cc1cc(C(=O)NC2Cc3ccccc3C2)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O10 compound treatment 0.317 -0.00225 -0.18 0.318 -0.00325 -0.3 -0.3367 -0.9726 1513763 Maybridge3_002430 Fc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3c(Cl)cncc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O11 compound treatment 0.331 0.0118 0.95 0.334 0.0127 1.16 1.4874 0.995 2076354 Maybridge3_002431 FC(F)(F)c1cccc(NC(=O)CSc2nccc(n2)c3cccs3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O12 compound treatment 0.331 0.0118 0.95 0.335 0.0138 1.25 1.5516 0.9907 1463776 Maybridge3_002432 COc1ccc(OCC(O)CNC(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O13 compound treatment 0.336 0.0168 1.35 0.336 0.0147 1.34 1.9005 1.0 1340924 Maybridge3_002433 Clc1cncc(Cl)c1N2CCCN(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O14 compound treatment 0.331 0.0118 0.95 0.332 0.0107 0.98 1.359 0.9999 1583531 Maybridge3_002434 OC(=O)c1ccccc1C(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O15 compound treatment 0.376 0.0568 4.57 0.376 0.0548 4.97 6.7455 0.9991 2076355 Maybridge3_002435 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3ccc4ccccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O16 compound treatment 0.365 0.0457 3.68 0.366 0.0447 4.06 5.4773 0.9988 2076356 Maybridge3_002436 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)Nc3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O17 compound treatment 0.331 0.0118 0.95 0.332 0.0107 0.98 1.359 0.9999 2076357 Maybridge3_002437 C(Sc1nccc(n1)c2cccs2)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O18 compound treatment 0.334 0.0147 1.19 0.337 0.0158 1.43 1.8508 0.9958 1522234 Maybridge3_002438 OC(=O)CC(CC(=O)Nc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O19 compound treatment 0.34 0.0208 1.67 0.337 0.0158 1.43 2.1924 0.997 1139394 Maybridge3_002439 Cc1cc(NC(=O)c2cc(oc2C)C(C)(C)C)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O20 compound treatment 0.336 0.0168 1.35 0.337 0.0158 1.43 1.9647 0.9996 1742988 Maybridge3_002440 CCc1ccnc(NS(=O)(=O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O21 compound treatment 0.469 0.15 12.06 0.456 0.135 12.23 17.1758 1.0 2076358 Maybridge3_002441 COC(=O)c1c(C)[nH]c(C)c1/C=C/2\C(=O)Nc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O22 compound treatment 0.338 0.0187 1.51 0.341 0.0198 1.79 2.3353 0.9964 1398636 Maybridge3_002442 O=C(Nc1ccccc1)c2nc(c3ccccc3)n(n2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O23 mock treatment 0.328 0.00875 0.7 0.33 0.00875 0.79 1.0599 0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 O24 positive control 0.092 -0.227 -18.3 0.093 -0.228 -20.72 -27.59 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P01 compound treatment 0.331 0.0118 0.95 0.331 0.00975 0.89 1.2949 0.9994 1134000 Maybridge3_002443 COc1cc2nc(oc(=O)c2cc1OC)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P02 compound treatment 0.329 0.00975 0.79 0.33 0.00875 0.79 1.1168 1.0 1218005 Maybridge3_002444 CC(C)(CC(=O)O)CC(=O)Nc1ccccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P03 compound treatment 0.326 0.00675 0.54 0.325 0.00375 0.34 0.625 0.9746 1223761 Maybridge3_002445 Cc1cccc2nc(oc(=O)c12)c3cc4ccccc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P04 compound treatment 0.318 -0.00125 -0.1 0.322 7.5E-4 0.07 -0.023 -0.1896 1330406 Maybridge3_002446 Fc1ccc(cc1)C(=O)C2CCN(Cc3c[nH]c(n3)c4ccccc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P05 compound treatment 0.332 0.0127 1.03 0.328 0.00675 0.61 1.1592 0.9696 1445374 Maybridge3_002447 OC(=O)C1=C(SCCS1)C(=O)NC2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P06 compound treatment 0.326 0.00675 0.54 0.328 0.00675 0.61 0.8176 0.9982 2076359 Maybridge3_002448 Cn1c(SCC(O)c2ccccc2)nnc1c3ccc4ccccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P07 compound treatment 0.317 -0.00225 -0.18 0.32 -0.00125 -0.11 -0.2083 -0.9746 1593773 Maybridge3_002449 C(N1CCN(Cc2ccccc2)CC1)c3c[nH]nc3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P08 compound treatment 0.327 0.00775 0.62 0.324 0.00275 0.25 0.6178 0.9191 1554006 Maybridge3_002450 Cn1nccc1NC(=O)CC(C)(C)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P09 compound treatment 0.328 0.00875 0.7 0.328 0.00675 0.61 0.9315 0.9976 1554978 Maybridge3_002451 CS(=O)(=O)Nc1ccc(cc1)c2cn3CCSc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P10 compound treatment 0.332 0.0127 1.03 0.331 0.00975 0.89 1.3518 0.9973 1570129 Maybridge3_002452 O=S(=O)(N(CCC#N)Cc1ccccc1)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P11 compound treatment 0.326 0.00675 0.54 0.321 -2.5E-4 -0.02 0.3683 0.677 1574234 Maybridge3_002453 Fc1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P12 compound treatment 0.329 0.00975 0.79 0.327 0.00575 0.52 0.9242 0.9803 1160319 Maybridge3_002454 COc1cc2CCN(C(C)c2cc1OC)C(=O)CCCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P13 compound treatment 0.339 0.0198 1.59 0.333 0.0118 1.07 1.8788 0.9811 1600120 Maybridge3_002455 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P14 compound treatment 0.331 0.0118 0.95 0.331 0.00975 0.89 1.2949 0.9994 2076360 Maybridge3_002456 COc1ccc(OCC(O)CN2CCS(=O)(=O)CC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P15 compound treatment 0.326 0.00675 0.54 0.329 0.00775 0.7 0.8818 0.9919 2076361 Maybridge3_002457 OC(CNC(=O)CC1(CC(=O)O)CCCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P16 compound treatment 0.339 0.0198 1.59 0.337 0.0158 1.43 2.1355 0.9986 2076362 Maybridge3_002458 O=C(COc1ccccc1N2CCCCC2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P17 compound treatment 0.329 0.00975 0.79 0.329 0.00775 0.7 1.0526 0.9985 2076363 Maybridge3_002459 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC(O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P18 compound treatment 0.325 0.00575 0.46 0.323 0.00175 0.16 0.4397 0.8983 1459782 Maybridge3_002460 NC(=O)C1CCN(CC1)c2ncccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P19 compound treatment 0.33 0.0107 0.87 0.328 0.00675 0.61 1.0454 0.9857 1570643 Maybridge3_002461 CN(C)c1ccc(NC(=O)CC(CC(=O)O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P20 compound treatment 0.329 0.00975 0.79 0.334 0.0127 1.16 1.3735 0.9821 1423361 Maybridge3_002462 OC(=O)C1CCN(CC1)C(=O)CCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P21 compound treatment 0.358 0.0388 3.12 0.356 0.0348 3.15 4.4369 1.0 1501068 Maybridge3_002463 COc1ccc(cc1)n2ncc(C(=O)N3CCN(CC3)c4ccc(F)cc4)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P22 compound treatment 0.329 0.00975 0.79 0.33 0.00875 0.79 1.1168 1.0 1170351 Maybridge3_002464 O=C1NCCCCC1NS(=O)(=O)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P23 mock treatment 0.32 7.5E-4 0.06 0.32 -0.00125 -0.11 -0.0375 -0.2919 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1437 P24 positive control 0.093 -0.226 -18.22 0.094 -0.227 -20.63 -27.4689 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A01 compound treatment 0.315 0.00444 0.36 0.314 0.00188 0.17 0.373 0.9425 2076364 Maybridge3_002465 CC(=O)Nc1ccc(NC(=O)c2ccc(nc2C)C(F)(F)F)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A02 compound treatment 0.284 -0.0266 -2.14 0.333 0.0209 1.89 -0.1726 -0.0604 2076365 Maybridge3_002466 CS/C(=N\c1ccccc1)/C(C#N)c2nc3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A03 compound treatment 0.316 0.00544 0.44 0.307 -0.00512 -0.47 -0.0193 -0.0303 1594582 Maybridge3_002467 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A04 compound treatment 0.305 -0.00556 -0.45 0.31 -0.00212 -0.19 -0.4531 -0.9291 1302412 Maybridge3_002468 CCOC(=O)C1CCCc2sc(N)c(C#N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A05 compound treatment 0.304 -0.00656 -0.53 0.309 -0.00312 -0.28 -0.5743 -0.9574 1198750 Maybridge3_002469 CCCCN1Cc2c([nH]c3cc(nn3c2=O)c4ccccc4)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A06 compound treatment 0.292 -0.0186 -1.49 0.318 0.00588 0.53 -0.6799 -0.4284 1250245 Maybridge3_002470 CCC1C(=C(N)Oc2c1c(=O)oc3ccccc23)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A07 compound treatment 0.302 -0.00856 -0.69 0.307 -0.00512 -0.47 -0.8165 -0.9817 2076366 Maybridge3_002471 Cc1c(CN2CCN(Cc3ccccc3)CC2)sc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A08 compound treatment 0.302 -0.00856 -0.69 0.312 -1.25E-4 -0.01 -0.4956 -0.7186 1724012 Maybridge3_002472 OC(=O)CCCC(=O)Nc1ccccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A09 compound treatment 0.301 -0.00956 -0.77 0.304 -0.00812 -0.74 -1.066 -0.9998 1447140 Maybridge3_002473 Clc1ccc(cc1)C(=O)N2CCc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A10 compound treatment 0.298 -0.0126 -1.01 0.31 -0.00212 -0.19 -0.8517 -0.827 1660895 Maybridge3_002474 O=C(NCCN1CCOCC1)c2ccc(cc2)n3cccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A11 compound treatment 0.306 -0.00456 -0.37 0.309 -0.00312 -0.28 -0.4604 -0.9918 1560444 Maybridge3_002475 Clc1c(sc2ccccc12)C(=O)Nc3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A12 compound treatment 0.308 -0.00256 -0.21 0.32 0.00788 0.71 0.3595 0.4833 1710184 Maybridge3_002476 CN(C1CCCCC1)C(=O)c2cnn(c2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A13 compound treatment 0.315 0.00444 0.36 0.314 0.00188 0.17 0.373 0.9425 2076367 Maybridge3_002477 CCOC(=O)C1CCN(CC1)C(=O)c2cc(C)nn2C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A14 compound treatment 0.305 -0.00556 -0.45 0.306 -0.00612 -0.56 -0.7099 -0.9943 2076368 Maybridge3_002478 CN(C1CCCCC1)C(=O)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A15 compound treatment 0.303 -0.00756 -0.61 0.308 -0.00412 -0.37 -0.6954 -0.9727 1269003 Maybridge3_002479 OC(=O)C1CCN(CC1)C(=O)c2ccc3nsnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A16 compound treatment 0.3 -0.0106 -0.85 0.309 -0.00312 -0.28 -0.802 -0.8945 1715937 Maybridge3_002480 CC(c1ccccc1)n2c(O)nnc2SCCS(=O)(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A17 compound treatment 0.416 0.105 8.49 0.313 8.75E-4 0.08 6.0599 0.7137 2076369 Maybridge3_002481 CC(C)N(Cc1ccccc1)C(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A18 compound treatment 0.312 0.00144 0.12 0.325 0.0129 1.17 0.9082 0.7734 1428809 Maybridge3_002482 CCOC(=O)N1CCc2c(C(=O)c3ccc(Cl)cc3)c(N)sc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A19 compound treatment 0.304 -0.00656 -0.53 0.314 0.00188 0.17 -0.2533 -0.4563 1712908 Maybridge3_002483 Cn1nccc1N2C(=O)C3=C(SCCS3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A20 compound treatment 0.306 -0.00456 -0.37 0.31 -0.00212 -0.19 -0.3962 -0.9548 2076370 Maybridge3_002484 C1CC1c2nnc(s2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A21 compound treatment 0.322 0.0114 0.92 0.305 -0.00712 -0.65 0.1939 0.1723 1377268 Maybridge3_002485 Cc1ccc2oc(=O)n(CCc3noc(n3)c4ccccc4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A22 compound treatment 0.321 0.0104 0.84 0.306 -0.00612 -0.56 0.2012 0.1996 2076371 Maybridge3_002486 Cc1nn(nc1c2nnc(o2)c3ccc(cc3)C(F)(F)F)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A23 mock treatment 0.298 -0.0126 -1.01 0.303 -0.00912 -0.83 -1.301 -0.9951 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 A24 positive control 0.08 -0.231 -18.57 0.085 -0.227 -20.62 -27.7065 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B01 compound treatment 0.325 0.0144 1.16 0.33 0.0179 1.62 1.9694 0.9866 1382501 Maybridge3_002487 CN(C1CCCCC1)S(=O)(=O)c2cn(C)c(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B02 compound treatment 0.324 0.0134 1.08 0.333 0.0209 1.89 2.105 0.9647 1296228 Maybridge3_002488 CCN(CC)c1nc(C)nc2n(c3ccccc3)c(=S)sc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B03 compound treatment 0.325 0.0144 1.16 0.339 0.0269 2.44 2.5471 0.9425 2076372 Maybridge3_002489 FC(F)(F)c1cccc(Oc2ccc(NC(=O)c3ccco3)cn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B04 compound treatment 0.325 0.0144 1.16 0.339 0.0269 2.44 2.5471 0.9425 2076373 Maybridge3_002490 Oc1nnc(SCC(=O)c2ccc(F)cc2)n1Cc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B05 compound treatment 0.328 0.0174 1.4 0.337 0.0249 2.26 2.5895 0.9739 1397082 Maybridge3_002491 O=C(N1CCCCC1)c2nc(c3ccccc3)n(n2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B06 compound treatment 0.313 0.00244 0.2 0.318 0.00588 0.53 0.5159 0.9078 1293338 Maybridge3_002492 O=C(NC1Cc2ccccc2C1)c3ccc4OCCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B07 compound treatment 0.354 0.0434 3.5 0.325 0.0129 1.17 3.2997 0.8947 1631504 Maybridge3_002493 OC(=O)c1ccc(CN2CCS(=O)(=O)CC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B08 compound treatment 0.331 0.0204 1.65 0.276 -0.0361 -3.28 -1.155 -0.3148 1435313 Maybridge3_002494 O=C(CCN1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B09 compound treatment 0.314 0.00344 0.28 0.323 0.0109 0.99 0.8937 0.8718 2076374 Maybridge3_002495 OC(=O)COCC(=O)Nc1ccc(cn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B10 compound treatment 0.312 0.00144 0.12 0.327 0.0149 1.35 1.0366 0.7649 2076375 Maybridge3_002496 OCc1cncn1Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B11 compound treatment 0.319 0.00844 0.68 0.322 0.00988 0.9 1.1143 0.9907 2076376 Maybridge3_002497 Oc1nnc(SCC(=O)Nc2ccccc2)n1C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B12 compound treatment 0.318 0.00744 0.6 0.332 0.0199 1.8 1.6992 0.8939 2076377 Maybridge3_002498 Fc1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B13 compound treatment 0.321 0.0104 0.84 0.323 0.0109 0.99 1.2923 0.9968 2076378 Maybridge3_002499 Cc1ccc(C)n1c2cc(n[nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B14 compound treatment 0.323 0.0124 1.0 0.328 0.0159 1.44 1.7271 0.9842 2076379 Maybridge3_002500 OC(=O)COCC(=O)Nc1cc(ccc1N2CCCC2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B15 compound treatment 0.179 -0.132 -10.59 0.335 0.0229 2.08 -6.023 -0.5579 2076380 Maybridge3_002501 CN(C(=O)c1cc(nn1C)C(C)(C)C)c2nnc(s2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B16 compound treatment 0.314 0.00344 0.28 0.339 0.0269 2.44 1.9207 0.7823 1590157 Maybridge3_002502 Clc1c(sc2ccccc12)C(=O)N3CCN(CC3)C(=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B17 compound treatment 0.323 0.0124 1.0 0.347 0.0349 3.17 2.9467 0.8875 1221841 Maybridge3_002503 COc1ccc-2c(NC(c3cccn32)c4ccccc4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B18 compound treatment 0.36 0.0494 3.98 0.32 0.00788 0.71 3.3205 0.8209 2076381 Maybridge3_002504 Cc1cc2c(NC(=O)CC(C)(C)CC(=O)O)cccc2nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B19 compound treatment 0.427 0.116 9.38 0.325 0.0129 1.17 7.4564 0.7891 1372217 Maybridge3_002505 O=C(Nc1ccc2[nH]ccc2c1)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B20 compound treatment 0.315 0.00444 0.36 0.352 0.0399 3.62 2.8121 0.7732 2076382 Maybridge3_002506 COc1ccc(cc1)C(=O)CSc2nnc(O)n2C3Cc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B21 compound treatment 0.312 0.00144 0.12 0.325 0.0129 1.17 0.9082 0.7734 2076383 Maybridge3_002507 CC(=O)Nc1ccc(NS(=O)(=O)c2cc(Cl)sc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B22 compound treatment 0.317 0.00644 0.52 0.323 0.0109 0.99 1.0646 0.9548 2076384 Maybridge3_002508 Fc1ccc(cc1)S(=O)(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B23 mock treatment 0.312 0.00144 0.12 0.319 0.00688 0.62 0.5231 0.8242 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 B24 positive control 0.081 -0.23 -18.49 0.085 -0.227 -20.62 -27.6495 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C01 compound treatment 0.316 0.00544 0.44 0.322 0.00988 0.9 0.9434 0.9457 1290341 Maybridge3_002509 CN(C)c1cccc2n(C)nc(NC(=O)c3cc(Cl)sc3Cl)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C02 compound treatment 0.325 0.0144 1.16 0.331 0.0189 1.71 2.0336 0.9822 1640390 Maybridge3_002510 N#CCSc1nnc2c3ccccc3[nH]c2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C03 compound treatment 0.306 -0.00456 -0.37 0.334 0.0219 1.99 1.1443 0.5667 1211683 Maybridge3_002511 Cc1nnsc1C(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C04 compound treatment 0.326 0.0154 1.24 0.331 0.0189 1.71 2.0905 0.9876 1285902 Maybridge3_002512 CCOC(=O)C1CCCc2sc(N)c(C(=O)OCC)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C05 compound treatment 0.319 0.00844 0.68 0.322 0.00988 0.9 1.1143 0.9907 1643574 Maybridge3_002513 CC(C)(C)c1cc2[nH]c3C(=O)N(Cc4ccccc4)Cc3c(=O)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C06 compound treatment 0.319 0.00844 0.68 0.319 0.00688 0.62 0.9217 0.9991 1224909 Maybridge3_002514 CC1CCc2c(C1)sc3nc(SCC(=O)N)n(c4ccccc4)c(=O)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C07 compound treatment 0.315 0.00444 0.36 0.323 0.0109 0.99 0.9507 0.9056 1502819 Maybridge3_002515 O=C(N1CCC2(CC1)OCCO2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C08 compound treatment 0.33 0.0194 1.57 0.317 0.00488 0.44 1.4197 0.8728 1120307 Maybridge3_002516 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C09 compound treatment 0.321 0.0104 0.84 0.319 0.00688 0.62 1.0356 0.9893 1304754 Maybridge3_002517 O=C(N1CCc2ccccc2C1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C10 compound treatment 0.332 0.0214 1.73 0.325 0.0129 1.17 2.0471 0.982 1677250 Maybridge3_002518 OC(=O)CSCC(=O)Nc1nc(cs1)c2ccc(F)c(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C11 compound treatment 0.354 0.0434 3.5 0.321 0.00888 0.81 3.043 0.8478 2076385 Maybridge3_002519 CN(C)c1ccc(cc1)C(=O)Nc2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C12 compound treatment 0.319 0.00844 0.68 0.326 0.0139 1.26 1.371 0.9581 2076386 Maybridge3_002520 CN(C1CCCCC1)C(=O)c2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C13 compound treatment 0.317 0.00644 0.52 0.346 0.0339 3.07 2.5408 0.8148 1688465 Maybridge3_002521 CCOC(=O)C1CCN(CC1)C(=O)c2cc(C)n(n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C14 compound treatment 0.31 -5.63E-4 -0.05 0.32 0.00788 0.71 0.4734 0.661 1633997 Maybridge3_002522 OC(=O)C1CCN(CC1)C(=O)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C15 compound treatment 0.324 0.0134 1.08 0.328 0.0159 1.44 1.7841 0.99 1300810 Maybridge3_002523 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C16 compound treatment 0.318 0.00744 0.6 0.322 0.00988 0.9 1.0573 0.9808 1622638 Maybridge3_002524 OCc1cccc(NS(=O)(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C17 compound treatment 0.327 0.0164 1.32 0.323 0.0109 0.99 1.634 0.9896 1270014 Maybridge3_002525 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C18 compound treatment 0.315 0.00444 0.36 0.321 0.00888 0.81 0.8223 0.9331 2076387 Maybridge3_002526 Cc1nnsc1c2nnc(o2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C19 compound treatment 0.319 0.00844 0.68 0.342 0.0299 2.71 2.398 0.8578 1619472 Maybridge3_002527 Cc1ccc2nc(cn2c1)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C20 compound treatment 0.322 0.0114 0.92 0.322 0.00988 0.9 1.2851 0.9999 2076388 Maybridge3_002528 CCN(C(=O)c1ccccc1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C21 compound treatment 0.312 0.00144 0.12 0.314 0.00188 0.17 0.2022 0.9824 1171814 Maybridge3_002529 Cc1ccc2oc(=O)n(CCc3noc(n3)c4cccs4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C22 compound treatment 0.327 0.0164 1.32 0.322 0.00988 0.9 1.5698 0.982 2076389 Maybridge3_002530 OC(=O)C1CCN(CC1)C(=O)c2sc3ccccc3c2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C23 mock treatment 0.306 -0.00456 -0.37 0.311 -0.00112 -0.1 -0.332 -0.8706 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 C24 positive control 0.085 -0.226 -18.16 0.089 -0.223 -20.25 -27.165 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D01 compound treatment 0.329 0.0184 1.48 0.332 0.0199 1.8 2.3255 0.9953 1589205 Maybridge3_002531 CN(C1CCCCC1)S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D02 compound treatment 0.321 0.0104 0.84 0.35 0.0379 3.44 3.0253 0.8548 2076390 Maybridge3_002532 C=CCn1c(=S)sc2c(ncnc12)N(Cc3ccccc3)Cc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D03 compound treatment 0.324 0.0134 1.08 0.323 0.0109 0.99 1.4632 0.9989 1657212 Maybridge3_002533 Fc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D04 compound treatment 0.327 0.0164 1.32 0.33 0.0179 1.62 2.0833 0.9949 1129462 Maybridge3_002534 OC(=O)CCCC(=O)Nc1ccc(Oc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D05 compound treatment 0.334 0.0234 1.89 0.327 0.0149 1.35 2.2893 0.9865 2076391 Maybridge3_002535 CCc1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D06 compound treatment 0.314 0.00344 0.28 0.328 0.0159 1.44 1.2147 0.8278 1309402 Maybridge3_002536 COC(=O)c1ccccc1NC(=O)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D07 compound treatment 0.337 0.0264 2.13 0.335 0.0229 2.08 2.9736 0.9999 1241410 Maybridge3_002537 CC(=O)Nc1ccc(NC(=O)CCCC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D08 compound treatment 0.329 0.0184 1.48 0.337 0.0249 2.26 2.6465 0.9793 2076392 Maybridge3_002538 FC(F)(F)c1ccc(cc1)C(=O)N2CCN(CC2)C(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D09 compound treatment 0.325 0.0144 1.16 0.336 0.0239 2.17 2.3545 0.9574 2076393 Maybridge3_002539 CCN(C(=O)c1cccc(OC)c1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D10 compound treatment 0.332 0.0214 1.73 0.4 0.0879 7.98 6.8609 0.8407 2076394 Maybridge3_002540 O=C1C(=CNc2[nH]ncc2c3ccccc3)C(=O)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D11 compound treatment 0.343 0.0324 2.61 0.327 0.0149 1.35 2.8018 0.9528 2076395 Maybridge3_002541 CC(c1ccccc1)n2c(O)nnc2SCC(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D12 compound treatment 0.33 0.0194 1.57 0.329 0.0169 1.53 2.1899 0.9999 1699769 Maybridge3_002542 Fc1cccc(NC(=O)C2CCCCC2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D13 compound treatment 0.328 0.0174 1.4 0.329 0.0169 1.53 2.076 0.9991 2076396 Maybridge3_002543 Cc1nnsc1c2nnc(o2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D14 compound treatment 0.442 0.131 10.58 0.322 0.00988 0.9 8.118 0.7643 1157677 Maybridge3_002544 Oc1nnc(SCc2csc(n2)c3ccccc3)n1Cc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D15 compound treatment 0.295 -0.0156 -1.25 0.328 0.0159 1.44 0.1328 0.0695 2076397 Maybridge3_002545 CN(Cc1nnc(o1)c2ccc3ccccc3c2)c4nnc(s4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D16 compound treatment 0.307 -0.00356 -0.29 0.321 0.00888 0.81 0.3668 0.4289 2076398 Maybridge3_002546 O=C(c1ccccc1)n2ccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D17 compound treatment 0.314 0.00344 0.28 0.335 0.0229 2.08 1.664 0.7943 2076399 Maybridge3_002547 CC(C)(CC(=O)O)CC(=O)N1CCCc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D18 compound treatment 0.317 0.00644 0.52 0.324 0.0119 1.08 1.1288 0.9437 2076400 Maybridge3_002548 Cc1cc2c(NC(=O)CCCC(=O)O)cccc2nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D19 compound treatment 0.323 0.0124 1.0 0.352 0.0399 3.62 3.2676 0.8701 1407604 Maybridge3_002549 O=C(Nc1ccc2[nH]ccc2c1)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D20 compound treatment 0.327 0.0164 1.32 0.337 0.0249 2.26 2.5326 0.9676 2076401 Maybridge3_002550 COc1ccc(cc1)C(=O)CSc2nnc(O)n2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D21 compound treatment 0.32 0.00944 0.76 0.32 0.00788 0.71 1.0428 0.9995 1129980 Maybridge3_002551 CC(=O)Nc1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D22 compound treatment 0.322 0.0114 0.92 0.325 0.0129 1.17 1.4776 0.9931 2076402 Maybridge3_002552 O=S(=O)(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D23 mock treatment 0.307 -0.00356 -0.29 0.311 -0.00112 -0.1 -0.2751 -0.9033 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 D24 positive control 0.084 -0.227 -18.24 0.089 -0.223 -20.25 -27.222 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E01 compound treatment 0.327 0.0164 1.32 0.332 0.0199 1.8 2.2116 0.9884 1532336 Maybridge3_002553 CC(C)(CC(=O)O)CC(=O)Nc1ccccc1N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E02 compound treatment 0.322 0.0114 0.92 0.34 0.0279 2.53 2.4404 0.9063 1372966 Maybridge3_002554 CCOC(=O)c1sc(Nc2ccccc2)c(c1N)c3nc4ccccc4[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E03 compound treatment 0.327 0.0164 1.32 0.341 0.0289 2.62 2.7893 0.9499 1196671 Maybridge3_002555 Nc1ccc(cc1)c2cn3CCSc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E04 compound treatment 0.306 -0.00456 -0.37 0.33 0.0179 1.62 0.8875 0.5335 1536363 Maybridge3_002556 Clc1ccc(Nc2c3CCCc3nc4ncnn24)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E05 compound treatment 0.323 0.0124 1.0 0.331 0.0189 1.71 1.9197 0.9673 1628086 Maybridge3_002557 CC(C)(C)c1cc2[nH]c3C(=O)N(Cc3c(=O)n2n1)C4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E06 compound treatment 0.321 0.0104 0.84 0.331 0.0189 1.71 1.8058 0.9463 1213119 Maybridge3_002558 Cc1ccc2nc(cn2c1)c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E07 compound treatment 0.334 0.0234 1.89 0.328 0.0159 1.44 2.3535 0.9911 1271739 Maybridge3_002559 O=C(N1CCC2(CC1)OCCO2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E08 compound treatment 0.328 0.0174 1.4 0.338 0.0259 2.35 2.6537 0.9698 1216881 Maybridge3_002560 Cc1cc(C)c2cc([nH]c2c1)C(=O)N(Cc3ccccc3)Cc4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E09 compound treatment 0.337 0.0264 2.13 0.33 0.0179 1.62 2.6527 0.991 1699580 Maybridge3_002561 Cc1cc(=O)oc2cc(NC(=O)CSCC(=O)O)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E10 compound treatment 0.33 0.0194 1.57 0.338 0.0259 2.35 2.7676 0.9805 1367028 Maybridge3_002562 OC(=O)COCC(=O)Nc1nc(cs1)c2ccc(F)c(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E11 compound treatment 0.327 0.0164 1.32 0.331 0.0189 1.71 2.1475 0.9919 2076403 Maybridge3_002563 Cc1nc(ccc1C(=O)Nc2ccccc2N3CCOCC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E12 compound treatment 0.327 0.0164 1.32 0.335 0.0229 2.08 2.4042 0.9764 2076404 Maybridge3_002564 CN(C1CCCCC1)C(=O)c2cccc(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E13 compound treatment 0.333 0.0224 1.81 0.347 0.0349 3.17 3.5161 0.9646 2076405 Maybridge3_002565 CCOC(=O)C1CCN(CC1)C(=O)c2cnn(c2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E14 compound treatment 0.32 0.00944 0.76 0.321 0.00888 0.81 1.107 0.9996 2076406 Maybridge3_002566 Cc1nnsc1c2nnc(o2)c3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E15 compound treatment 0.33 0.0194 1.57 0.335 0.0229 2.08 2.575 0.9903 1469872 Maybridge3_002567 Cc1ccc2nc(cn2c1)c3ccc(s3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E16 compound treatment 0.322 0.0114 0.92 0.329 0.0169 1.53 1.7344 0.9704 1646775 Maybridge3_002568 Cn1nc(cc1NC(=O)CSCC(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E17 compound treatment 0.357 0.0464 3.74 0.321 0.00888 0.81 3.2138 0.8402 1498121 Maybridge3_002569 CC(C)N(Cc1ccccc1)S(=O)(=O)c2c(C)noc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E18 compound treatment 0.323 0.0124 1.0 0.32 0.00788 0.71 1.2137 0.9863 1267162 Maybridge3_002570 O=C(Nc1ccccc1C#N)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E19 compound treatment 0.315 0.00444 0.36 0.321 0.00888 0.81 0.8223 0.9331 1528710 Maybridge3_002571 Clc1ccc(Cl)c(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E20 compound treatment 0.325 0.0144 1.16 0.306 -0.00612 -0.56 0.4289 0.3329 2076407 Maybridge3_002572 CC(C)(C)C(=O)CSc1nc2cc(Cl)c(Cl)cc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E21 compound treatment 0.331 0.0204 1.65 0.339 0.0269 2.44 2.8887 0.9816 1134559 Maybridge3_002573 Clc1ccc(CN(Cc2cccnc2)C(=O)c3ccccc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E22 compound treatment 0.329 0.0184 1.48 0.318 0.00588 0.53 1.4269 0.9045 1309425 Maybridge3_002574 O=C(Nc1ccc2[nH]ccc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E23 mock treatment 0.308 -0.00256 -0.21 0.307 -0.00512 -0.47 -0.4749 -0.9331 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 E24 positive control 0.087 -0.224 -18.0 0.092 -0.22 -19.98 -26.8586 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F01 compound treatment 0.336 0.0254 2.05 0.331 0.0189 1.71 2.6599 0.9961 1622361 Maybridge3_002575 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N(C)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F02 compound treatment 0.325 0.0144 1.16 0.337 0.0249 2.26 2.4187 0.9524 2076408 Maybridge3_002576 CCOC(=O)C1CCc2sc(N)c(C#N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F03 compound treatment 0.328 0.0174 1.4 0.339 0.0269 2.44 2.7179 0.9656 1420258 Maybridge3_002577 O=C(Nc1ccc(cc1)N2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F04 compound treatment 0.324 0.0134 1.08 0.332 0.0199 1.8 2.0408 0.9701 1608708 Maybridge3_002578 OC(=O)CCC(=O)Nc1ccc(Oc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F05 compound treatment 0.343 0.0324 2.61 0.351 0.0389 3.53 4.3422 0.989 1648287 Maybridge3_002579 CC(C)(C)c1ccc(Oc2ccc(NC(=O)CCCC(=O)O)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F06 compound treatment 0.327 0.0164 1.32 0.334 0.0219 1.99 2.34 0.9806 1386552 Maybridge3_002580 O=C(NCc1ccco1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F07 compound treatment 0.34 0.0294 2.37 0.334 0.0219 1.99 3.0802 0.9961 2076409 Maybridge3_002581 CC(=O)Nc1ccc(NC(=O)CC(C)(C)CC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F08 compound treatment 0.334 0.0234 1.89 0.386 0.0739 6.71 6.0762 0.8722 2076410 Maybridge3_002582 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)CSCC(=O)O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F09 compound treatment 0.323 0.0124 1.0 0.316 0.00388 0.35 0.9569 0.9015 2076411 Maybridge3_002583 CCN(C(=O)c1cccs1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F10 compound treatment 0.339 0.0284 2.29 0.354 0.0419 3.8 4.307 0.9706 2076412 Maybridge3_002584 Cc1cn[nH]c1NC=C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F11 compound treatment 0.323 0.0124 1.0 0.331 0.0189 1.71 1.9197 0.9673 2076413 Maybridge3_002585 Cc1nnsc1c2nnc(SCC(=O)c3ccc(F)cc3)n2C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F12 compound treatment 0.317 0.00644 0.52 0.322 0.00988 0.9 1.0004 0.9661 2076414 Maybridge3_002586 OC(=O)CSCC(=O)Nc1cccc(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F13 compound treatment 0.334 0.0234 1.89 0.324 0.0119 1.08 2.0967 0.9647 2076415 Maybridge3_002587 FC(F)(F)c1ccccc1c2nnc(o2)c3sccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F14 compound treatment 0.326 0.0154 1.24 0.325 0.0129 1.17 1.7054 0.9995 2076416 Maybridge3_002588 Oc1nnc(SCc2nc3ccccc3s2)n1Cc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F15 compound treatment 0.3 -0.0106 -0.85 0.33 0.0179 1.62 0.5459 0.298 1339281 Maybridge3_002589 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N(Cc2ccccc2)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F16 compound treatment 0.317 0.00644 0.52 0.326 0.0139 1.26 1.2571 0.923 2076417 Maybridge3_002590 O=C(c1ccco1)n2ccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F17 compound treatment 0.361 0.0504 4.06 0.351 0.0389 3.53 5.3671 0.9975 1268596 Maybridge3_002591 Oc1ccccc1C(=O)NC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F18 compound treatment 0.324 0.0134 1.08 0.332 0.0199 1.8 2.0408 0.9701 2076418 Maybridge3_002592 Cn1nc(cc1NC(=O)COc2ccc(Cl)cc2Cl)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F19 compound treatment 0.322 0.0114 0.92 0.351 0.0389 3.53 3.1465 0.8628 1590476 Maybridge3_002593 Cc1nn(nc1C(=O)Nc2ccc3[nH]ccc3c2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F20 compound treatment 0.321 0.0104 0.84 0.329 0.0169 1.53 1.6774 0.9601 2076419 Maybridge3_002594 COc1ccc(NC(=O)CC(C)(C)CC(=O)O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F21 compound treatment 0.32 0.00944 0.76 0.086 -0.226 -20.53 -13.9765 -0.6805 2076420 Maybridge3_002595 CCOC(=O)c1cnn(C(=S)N)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F22 compound treatment 0.308 -0.00256 -0.21 0.325 0.0129 1.17 0.6805 0.5734 2076421 Maybridge3_002596 Clc1ccc(cc1)S(=O)(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F23 mock treatment 0.311 4.37E-4 0.04 0.312 -1.25E-4 -0.01 0.0169 0.4563 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 F24 positive control 0.085 -0.226 -18.16 0.091 -0.221 -20.07 -27.0366 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G01 compound treatment 0.325 0.0144 1.16 0.334 0.0219 1.99 2.2261 0.9675 1268780 Maybridge3_002597 OC(=O)CC1(CC(=O)Nc2ccccc2N3CCOCC3)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G02 compound treatment 0.322 0.0114 0.92 0.331 0.0189 1.71 1.8628 0.9576 1521013 Maybridge3_002598 Cc1cc(C)n(n1)c2cc(nc3ncnn23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G03 compound treatment 0.317 0.00644 0.52 0.339 0.0269 2.44 2.0915 0.8386 1459902 Maybridge3_002599 Cc1cc(C)c2cc([nH]c2c1)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G04 compound treatment 0.331 0.0204 1.65 0.331 0.0189 1.71 2.3752 0.9998 2076422 Maybridge3_002600 Cc1cc(C)n(n1)c2ncnc3n(ncc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G05 compound treatment 0.32 0.00944 0.76 0.328 0.0159 1.44 1.5563 0.9553 1275540 Maybridge3_002601 CCOC(=O)C1=C(O)C(=O)N(Cc2ccco2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G06 compound treatment 0.317 0.00644 0.52 0.326 0.0139 1.26 1.2571 0.923 1472186 Maybridge3_002602 Cc1ccc2nc(cn2c1)c3cccc(C#N)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G07 compound treatment 0.317 0.00644 0.52 0.326 0.0139 1.26 1.2571 0.923 1201007 Maybridge3_002603 Cc1cc(no1)C(=O)N2CCC3(CC2)OCCO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G08 compound treatment 0.331 0.0204 1.65 0.318 0.00588 0.53 1.5408 0.8906 1553971 Maybridge3_002604 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccc(cc3)n4cccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G09 compound treatment 0.332 0.0214 1.73 0.327 0.0149 1.35 2.1754 0.9926 1637263 Maybridge3_002605 Cc1cc(=O)oc2cc(NC(=O)CCC(=O)O)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G10 compound treatment 0.328 0.0174 1.4 0.337 0.0249 2.26 2.5895 0.9739 2076423 Maybridge3_002606 FC(F)(F)c1ccc(NS(=O)(=O)c2ccc(s2)c3ccccn3)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G11 compound treatment 0.33 0.0194 1.57 0.346 0.0339 3.07 3.2811 0.9509 1402163 Maybridge3_002607 Cc1onc(c1C(=O)Nc2ccccc2N3CCOCC3)c4c(F)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G12 compound treatment 0.326 0.0154 1.24 0.319 0.00688 0.62 1.3203 0.9492 1544242 Maybridge3_002608 CN(C1CCCCC1)S(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G13 compound treatment 0.331 0.0204 1.65 0.343 0.0309 2.8 3.1454 0.9678 1214229 Maybridge3_002609 CCOC(=O)C1CCN(CC1)C(=O)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G14 compound treatment 0.322 0.0114 0.92 0.329 0.0169 1.53 1.7344 0.9704 1212213 Maybridge3_002610 CN(CCc1ccccn1)C(=O)c2sc3ccccc3c2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G15 compound treatment 0.32 0.00944 0.76 0.31 -0.00212 -0.19 0.401 0.5114 1479373 Maybridge3_002611 O=C(Nc1cccc(COC(=O)c2ccccc2)c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G16 compound treatment 0.362 0.0514 4.14 0.332 0.0199 1.8 4.2046 0.9306 1688445 Maybridge3_002612 Cn1nc(cc1NC(=O)CC(C)(C)CC(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G17 compound treatment 0.338 0.0274 2.21 0.324 0.0119 1.08 2.3245 0.9456 2076424 Maybridge3_002613 CCc1ccc(cc1)C(=O)N(Cc2ccccc2)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G18 compound treatment 0.317 0.00644 0.52 0.322 0.00988 0.9 1.0004 0.9661 2076425 Maybridge3_002614 O=S(=O)(Nc1ccccc1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G19 compound treatment 0.337 0.0264 2.13 0.325 0.0129 1.17 2.3318 0.9601 1126160 Maybridge3_002615 Fc1ccc(cc1)C(=O)Nc2cccnc2Oc3ncnc4cc(Cl)ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G20 compound treatment 0.334 0.0234 1.89 0.322 0.00988 0.9 1.9684 0.9421 1662636 Maybridge3_002616 CN(C)CCNC(=O)c1c(C)onc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G21 compound treatment 0.322 0.0114 0.92 0.334 0.0219 1.99 2.0553 0.939 1398056 Maybridge3_002617 Clc1ccc(CN(Cc2cccnc2)C(=O)c3cccs3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G22 compound treatment 0.316 0.00544 0.44 0.318 0.00588 0.53 0.6867 0.9952 1331815 Maybridge3_002618 O=C(Nc1ccc2[nH]ccc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G23 mock treatment 0.312 0.00144 0.12 0.31 -0.00212 -0.19 -0.0545 -0.2424 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 G24 positive control 0.087 -0.224 -18.0 0.094 -0.218 -19.8 -26.7302 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H01 compound treatment 0.342 0.0314 2.53 0.332 0.0199 1.8 3.0658 0.9862 1303425 Maybridge3_002619 COC(=O)c1ccc(o1)S(=O)(=O)N(C)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H02 compound treatment 0.326 0.0154 1.24 0.331 0.0189 1.71 2.0905 0.9876 1176860 Maybridge3_002620 Clc1ccccc1Cn2nnc3c(=O)[nH]cnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H03 compound treatment 0.328 0.0174 1.4 0.333 0.0209 1.89 2.3328 0.9891 1453343 Maybridge3_002621 Cc1cc(no1)C(=O)Nc2ccc(cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H04 compound treatment 0.32 0.00944 0.76 0.328 0.0159 1.44 1.5563 0.9553 1593776 Maybridge3_002622 C1CCN(CC1)c2ccccc2n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H05 compound treatment 0.331 0.0204 1.65 0.349 0.0369 3.35 3.5306 0.9466 1253368 Maybridge3_002623 CC(C)(C)c1ccc(Oc2ccc(NC(=O)CSCC(=O)O)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H06 compound treatment 0.33 0.0194 1.57 0.336 0.0239 2.17 2.6392 0.9872 1189308 Maybridge3_002624 O=C(N1CCCCC1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H07 compound treatment 0.326 0.0154 1.24 0.33 0.0179 1.62 2.0263 0.9913 1444774 Maybridge3_002625 CC(=O)Nc1ccc(NC(=O)CC2(CC(=O)O)CCCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H08 compound treatment 0.31 -5.63E-4 -0.05 0.374 0.0619 5.62 3.9394 0.7014 1599704 Maybridge3_002626 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)CCC(=O)O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H09 compound treatment 0.329 0.0184 1.48 0.333 0.0209 1.89 2.3897 0.9927 2076426 Maybridge3_002627 O=S(=O)(N1CCOCC1)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H10 compound treatment 0.323 0.0124 1.0 0.314 0.00188 0.17 0.8285 0.8156 1276045 Maybridge3_002628 S=c1sc2ccccc2n1CSc3nc4ccccc4[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H11 compound treatment 0.336 0.0254 2.05 0.328 0.0159 1.44 2.4674 0.9852 1470445 Maybridge3_002629 COc1ccc(cc1)C(=O)c2c(N)sc3CN(CCc23)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H12 compound treatment 0.317 0.00644 0.52 0.318 0.00588 0.53 0.7436 0.9999 2076427 Maybridge3_002630 OC(=O)COCC(=O)Nc1cccc(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H13 compound treatment 0.345 0.0344 2.77 0.361 0.0489 4.44 5.0979 0.9744 2076428 Maybridge3_002631 NC(=O)C1CCN(CC1)C(=O)c2ccc(Oc3cc(Cl)cc(Cl)c3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H14 compound treatment 0.337 0.0264 2.13 0.332 0.0199 1.8 2.7811 0.9966 2076429 Maybridge3_002632 Oc1nnc(SCC(=O)c2csc3ccccc23)n1Cc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H15 compound treatment 0.262 -0.0486 -3.91 0.322 0.00988 0.9 -2.1314 -0.5312 1309383 Maybridge3_002633 COC(=O)c1ccc(o1)S(=O)(=O)N(Cc2ccccc2)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H16 compound treatment 0.337 0.0264 2.13 0.32 0.00788 0.71 2.0108 0.8954 2076430 Maybridge3_002634 COc1cccc(c1)C(=O)n2ccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H17 compound treatment 0.331 0.0204 1.65 0.338 0.0259 2.35 2.8245 0.9849 2076431 Maybridge3_002635 Oc1ccccc1C(=O)NC(=O)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H18 compound treatment 0.32 0.00944 0.76 0.332 0.0199 1.8 1.8131 0.9262 1760439 Maybridge3_002636 COc1ccc(CCNC(=O)c2ccc3nccnc3c2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H19 compound treatment 0.325 0.0144 1.16 0.315 0.00288 0.26 1.0066 0.8448 2076432 Maybridge3_002637 O=S(=O)(Nc1ccc2[nH]ccc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H20 compound treatment 0.33 0.0194 1.57 0.331 0.0189 1.71 2.3183 0.999 2076433 Maybridge3_002638 COc1ccc(NC(=O)CCC(=O)O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H21 compound treatment 0.32 0.00944 0.76 0.325 0.0129 1.17 1.3638 0.9783 1193474 Maybridge3_002639 NC(=O)c1nnc2ccccc2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H22 compound treatment 0.318 0.00744 0.6 0.33 0.0179 1.62 1.5708 0.9082 2076434 Maybridge3_002640 Cc1oc(cc1C(=O)NCc2ccncc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H23 mock treatment 0.31 -5.63E-4 -0.05 0.311 -0.00112 -0.1 -0.1042 -0.9331 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 H24 positive control 0.087 -0.224 -18.0 0.094 -0.218 -19.8 -26.7302 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I01 compound treatment 0.331 0.0204 1.65 0.329 0.0169 1.53 2.2469 0.9994 2076435 Maybridge3_002641 O=C1CCC(=O)N1c2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I02 compound treatment 0.32 0.00944 0.76 0.336 0.0239 2.17 2.0698 0.9013 1565907 Maybridge3_002642 CCOC(=O)CSc1cc(nc2ncnn12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I03 compound treatment 0.331 0.0204 1.65 0.332 0.0199 1.8 2.4394 0.9989 1140136 Maybridge3_002643 CN(C1CCN(C)CC1)C(=O)c2cc3c(C)cc(C)cc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I04 compound treatment 0.327 0.0164 1.32 0.325 0.0129 1.17 1.7623 0.9981 2076436 Maybridge3_002644 C=CCSc1ncnc2n(ncc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I05 compound treatment 0.33 0.0194 1.57 0.338 0.0259 2.35 2.7676 0.9805 1249463 Maybridge3_002645 O=C(Nc1ccc2OCCOc2c1)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I06 compound treatment 0.321 0.0104 0.84 0.329 0.0169 1.53 1.6774 0.9601 1415369 Maybridge3_002646 Nc1nc(cs1)c2cc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I07 compound treatment 0.321 0.0104 0.84 0.33 0.0179 1.62 1.7416 0.9531 2076437 Maybridge3_002647 Cc1nc(ccc1C(=O)N2CCC3(CC2)OCCO3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I08 compound treatment 0.328 0.0174 1.4 0.33 0.0179 1.62 2.1402 0.9974 1553575 Maybridge3_002648 O=C(Nc1ccc(cc1)N2CCOCC2)c3ccc(cc3)n4cccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I09 compound treatment 0.338 0.0274 2.21 0.335 0.0229 2.08 3.0305 0.9995 2076438 Maybridge3_002649 Cc1cc(=O)oc2cc(NC(=O)c3ccccc3C(=O)O)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I10 compound treatment 0.331 0.0204 1.65 0.328 0.0159 1.44 2.1827 0.9978 1419968 Maybridge3_002650 O=C(Nc1nnc(s1)C2CC2)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I11 compound treatment 0.346 0.0354 2.85 0.332 0.0199 1.8 3.2935 0.9755 1719358 Maybridge3_002651 O=S(=O)(Nc1ccccc1N2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I12 compound treatment 0.327 0.0164 1.32 0.307 -0.00512 -0.47 0.607 0.4326 1436631 Maybridge3_002652 CN(C1CCCCC1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I13 compound treatment 0.334 0.0234 1.89 0.336 0.0239 2.17 2.867 0.9976 2076439 Maybridge3_002653 Cc1cc(C(=O)N2CCC(CC2)C(=O)O)c(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I14 compound treatment 0.334 0.0234 1.89 0.335 0.0229 2.08 2.8028 0.9989 1337698 Maybridge3_002654 CN(CCc1ccccn1)C(=O)c2cccnc2Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I15 compound treatment 0.349 0.0384 3.1 0.312 -1.25E-4 -0.01 2.1806 0.7045 1638348 Maybridge3_002655 CCOC(=O)C1CCN(Cc2csc(n2)c3cccs3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I16 compound treatment 0.306 -0.00456 -0.37 0.319 0.00688 0.62 0.1815 0.2506 1366264 Maybridge3_002656 OC(=O)CSCC(=O)N1CCN(CC1)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I17 compound treatment 0.336 0.0254 2.05 0.335 0.0229 2.08 2.9167 1.0 2076440 Maybridge3_002657 CC(C)N(Cc1ccccc1)C(=O)c2snnc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I18 compound treatment 0.334 0.0234 1.89 0.326 0.0139 1.26 2.2251 0.9807 2076441 Maybridge3_002658 Fc1ccc(cc1)S(=O)(=O)Nc2ccccc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I19 compound treatment 0.334 0.0234 1.89 0.335 0.0229 2.08 2.8028 0.9989 1222151 Maybridge3_002659 Clc1ccc2c(Oc3ncccc3NC(=O)c4cccs4)ncnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I20 compound treatment 0.34 0.0294 2.37 0.335 0.0229 2.08 3.1444 0.9978 1494278 Maybridge3_002660 Cc1onc(c1C(=O)NCCN2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I21 compound treatment 0.325 0.0144 1.16 0.319 0.00688 0.62 1.2634 0.9574 2076442 Maybridge3_002661 NC(=O)c1cccc(CSCc2csc3ccccc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I22 compound treatment 0.331 0.0204 1.65 0.329 0.0169 1.53 2.2469 0.9994 1206272 Maybridge3_002662 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1C3Cc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I23 mock treatment 0.315 0.00444 0.36 0.315 0.00288 0.26 0.4372 0.9881 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 I24 positive control 0.089 -0.222 -17.84 0.095 -0.217 -19.71 -26.5521 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J01 compound treatment 0.332 0.0214 1.73 0.342 0.0299 2.71 3.1382 0.9762 1416751 Maybridge3_002663 Cc1nc(sc1C(=O)Nc2ccc(cc2)S(=O)(=O)N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J02 compound treatment 0.336 0.0254 2.05 0.339 0.0269 2.44 3.1734 0.9962 1524802 Maybridge3_002664 Clc1ccc(Cn2nnc3c(=O)[nH]cnc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J03 compound treatment 0.303 -0.00756 -0.61 0.329 0.0169 1.53 0.6525 0.3958 1716029 Maybridge3_002665 Cn1cnc(c1)S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J04 compound treatment 0.335 0.0244 1.97 0.327 0.0149 1.35 2.3462 0.9831 2076443 Maybridge3_002666 O=S(=O)(Nc1cccc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J05 compound treatment 0.331 0.0204 1.65 0.328 0.0159 1.44 2.1827 0.9978 2076444 Maybridge3_002667 O=C(NCc1cccnc1)c2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J06 compound treatment 0.311 4.37E-4 0.04 0.333 0.0209 1.89 1.3648 0.7201 1180553 Maybridge3_002668 CN(CCc1ccccn1)C(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J07 compound treatment 0.328 0.0174 1.4 0.328 0.0159 1.44 2.0118 0.9999 1472138 Maybridge3_002669 CC(=O)Nc1ccc(NC(=O)CSCC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J08 compound treatment 0.318 0.00744 0.6 0.368 0.0559 5.07 4.0098 0.7852 2076445 Maybridge3_002670 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)CC(C)(C)CC(=O)O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J09 compound treatment 0.329 0.0184 1.48 0.33 0.0179 1.62 2.1972 0.999 2076446 Maybridge3_002671 O=S(=O)(NC1Cc2ccccc2C1)c3ccc(cc3)c4csnn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J10 compound treatment 0.326 0.0154 1.24 0.318 0.00588 0.53 1.2561 0.9286 1430973 Maybridge3_002672 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J11 compound treatment 0.318 0.00744 0.6 0.327 0.0149 1.35 1.3783 0.9331 1705758 Maybridge3_002673 OC(=O)CSCC(=O)Nc1cc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J12 compound treatment 0.348 0.0374 3.01 0.341 0.0289 2.62 3.9851 0.9976 2076447 Maybridge3_002674 COC(=O)c1sc(cc1NC(=O)/C=C/C(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J13 compound treatment 0.327 0.0164 1.32 0.309 -0.00312 -0.28 0.7354 0.5432 1305677 Maybridge3_002675 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NCc3ccco3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J14 compound treatment 0.316 0.00544 0.44 0.374 0.0619 5.62 4.2811 0.7599 2076448 Maybridge3_002676 Cc1nc(Nc2ccccc2)sc1C(=O)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J15 compound treatment 0.397 0.0864 6.96 0.323 0.0109 0.99 5.6198 0.7994 1127811 Maybridge3_002677 CN(C1CCCCC1)C(=O)c2ccc3nccnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J16 compound treatment 0.343 0.0324 2.61 0.328 0.0159 1.44 2.866 0.9607 2076449 Maybridge3_002678 Cc1noc(C)c1C(=O)n2ccc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J17 compound treatment 0.329 0.0184 1.48 0.345 0.0329 2.98 3.1599 0.9481 1314068 Maybridge3_002679 COc1cccc(c1)C(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J18 compound treatment 0.317 0.00644 0.52 0.33 0.0179 1.62 1.5139 0.8888 2076450 Maybridge3_002680 COc1ccc(OCCNC(=O)c2ccc3nccnc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J19 compound treatment 0.325 0.0144 1.16 0.326 0.0139 1.26 1.7127 0.9992 1538643 Maybridge3_002681 Cn1cnc(c1)S(=O)(=O)Nc2ccc3[nH]ccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J20 compound treatment 0.321 0.0104 0.84 0.32 0.00788 0.71 1.0998 0.9968 2076451 Maybridge3_002682 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J21 compound treatment 0.341 0.0304 2.45 0.28 -0.0321 -2.92 -0.3288 -0.0863 2076452 Maybridge3_002683 N#CC(Sc1nc2ccccc2[nH]1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J22 compound treatment 0.319 0.00844 0.68 0.313 8.75E-4 0.08 0.5366 0.7844 2076453 Maybridge3_002684 CC(C)(CC(=O)Nc1cccnc1)Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J23 mock treatment 0.313 0.00244 0.2 0.31 -0.00212 -0.19 0.0024 0.0087 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 J24 positive control 0.089 -0.222 -17.84 0.095 -0.217 -19.71 -26.5521 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K01 compound treatment 0.335 0.0244 1.97 0.337 0.0249 2.26 2.9881 0.9977 1402522 Maybridge3_002685 O=C1CSCC(=O)N1c2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K02 compound treatment 0.322 0.0114 0.92 0.343 0.0309 2.8 2.633 0.8925 1240335 Maybridge3_002686 Cc1cc(nc2oc(C(=O)c3ccc(Cl)cc3)c(N)c12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K03 compound treatment 0.326 0.0154 1.24 0.337 0.0249 2.26 2.4756 0.9605 2076454 Maybridge3_002687 Cc1cc(C)c2cc([nH]c2c1)C(=O)NCCNc3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K04 compound treatment 0.321 0.0104 0.84 0.328 0.0159 1.44 1.6133 0.9671 1590311 Maybridge3_002688 CCOC(=O)CSc1ncnc2n(ncc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K05 compound treatment 0.328 0.0174 1.4 0.324 0.0119 1.08 1.7551 0.9915 1553029 Maybridge3_002689 O=C(Nc1ccc2OCCOc2c1)c3cncc(c3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K06 compound treatment 0.325 0.0144 1.16 0.344 0.0319 2.89 2.868 0.9198 2076455 Maybridge3_002690 O=C(Nc1ccccc1)c2nnc(o2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K07 compound treatment 0.317 0.00644 0.52 0.32 0.00788 0.71 0.872 0.9876 1625571 Maybridge3_002691 O=S(=O)(N1CCC2(CC1)OCCO2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K08 compound treatment 0.306 -0.00456 -0.37 0.35 0.0379 3.44 2.1712 0.628 2076456 Maybridge3_002692 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3ccc(cc3)n4cccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K09 compound treatment 0.343 0.0324 2.61 0.327 0.0149 1.35 2.8018 0.9528 2076457 Maybridge3_002693 Cc1cc(=O)oc2cc(NC(=O)CC3(CC(=O)O)CCCC3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K10 compound treatment 0.323 0.0124 1.0 0.321 0.00888 0.81 1.2778 0.9942 1127714 Maybridge3_002694 O=C(Nc1nnc(s1)C2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K11 compound treatment 0.316 0.00544 0.44 0.329 0.0169 1.53 1.3927 0.8742 1321401 Maybridge3_002695 O=S(=O)(Nc1ccccc1N2CCOCC2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K12 compound treatment 0.324 0.0134 1.08 0.307 -0.00512 -0.47 0.4362 0.3703 2076458 Maybridge3_002696 CN(C1CCCCC1)S(=O)(=O)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K13 compound treatment 0.319 0.00844 0.68 0.322 0.00988 0.9 1.1143 0.9907 1549363 Maybridge3_002697 Cc1cc(C(=O)N2CCC(CC2)C(=O)O)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K14 compound treatment 0.328 0.0174 1.4 0.324 0.0119 1.08 1.7551 0.9915 2076459 Maybridge3_002698 Cc1ccc(cc1)S(=O)(=O)CCSc2nnc(O)n2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K15 compound treatment 0.346 0.0354 2.85 0.327 0.0149 1.35 2.9726 0.9416 1147820 Maybridge3_002699 C(N1CCSCC1)c2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K16 compound treatment 0.324 0.0134 1.08 0.33 0.0179 1.62 1.9125 0.9806 1580980 Maybridge3_002700 CCOC(=O)Cc1csc(NS(=O)(=O)c2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K17 compound treatment 0.322 0.0114 0.92 0.319 0.00688 0.62 1.0925 0.982 2076460 Maybridge3_002701 CC(C)N(Cc1ccccc1)C(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K18 compound treatment 0.328 0.0174 1.4 0.322 0.00988 0.9 1.6267 0.9765 1174382 Maybridge3_002702 COc1c(Cl)scc1C(=O)Nc2nnc(s2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K19 compound treatment 0.335 0.0244 1.97 0.364 0.0519 4.71 4.7211 0.9251 1290748 Maybridge3_002703 Clc1ccc2c(OCC(=O)c3ccc4OCCCOc4c3)ncnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K20 compound treatment 0.317 0.00644 0.52 0.326 0.0139 1.26 1.2571 0.923 1407581 Maybridge3_002704 CC(C)(C)c1cc(NS(=O)(=O)c2ccc(C#N)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K21 compound treatment 0.332 0.0214 1.73 0.334 0.0219 1.99 2.6247 0.9976 2076461 Maybridge3_002705 CCOC(=O)CSc1nnc(c2ccccc2)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K22 compound treatment 0.32 0.00944 0.76 0.327 0.0149 1.35 1.4921 0.963 2076462 Maybridge3_002706 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K23 mock treatment 0.31 -5.63E-4 -0.05 0.311 -0.00112 -0.1 -0.1042 -0.9331 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 K24 positive control 0.09 -0.221 -17.76 0.097 -0.215 -19.53 -26.3668 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L01 compound treatment 0.337 0.0264 2.13 0.344 0.0319 2.89 3.5513 0.9886 2076463 Maybridge3_002707 NS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L02 compound treatment 0.334 0.0234 1.89 0.316 0.00388 0.35 1.5833 0.8247 2076464 Maybridge3_002708 CCOC(=O)CSc1ncnc2sc3CCCCc3c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L03 compound treatment 0.326 0.0154 1.24 0.328 0.0159 1.44 1.898 0.9973 1455383 Maybridge3_002709 Cc1noc(C)c1S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L04 compound treatment 0.32 0.00944 0.76 0.336 0.0239 2.17 2.0698 0.9013 2076465 Maybridge3_002710 O=S(=O)(Nc1cccc2ccccc12)c3cccc4nonc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L05 compound treatment 0.331 0.0204 1.65 0.334 0.0219 1.99 2.5678 0.9956 2076466 Maybridge3_002711 Fc1ccc(CNC(=O)CCc2nc(no2)c3ccccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L06 compound treatment 0.328 0.0174 1.4 0.337 0.0249 2.26 2.5895 0.9739 2076467 Maybridge3_002712 CN(CCc1ccccn1)C(=O)c2nn(nc2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L07 compound treatment 0.337 0.0264 2.13 0.329 0.0169 1.53 2.5885 0.987 2076468 Maybridge3_002713 Cc1nc(ccc1C(=O)Nc2ccc(cn2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L08 compound treatment 0.333 0.0224 1.81 0.34 0.0279 2.53 3.0668 0.9864 2076469 Maybridge3_002714 CS(=O)(=O)c1ccc(cc1)C2=Nn3c(nnc3SC2)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L09 compound treatment 0.331 0.0204 1.65 0.329 0.0169 1.53 2.2469 0.9994 2076470 Maybridge3_002715 CN(C)c1ccc(NS(=O)(=O)c2ccc(cc2)c3csnn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L10 compound treatment 0.328 0.0174 1.4 0.337 0.0249 2.26 2.5895 0.9739 2076471 Maybridge3_002716 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3ccc(s3)c4ccon4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L11 compound treatment 0.32 0.00944 0.76 0.33 0.0179 1.62 1.6847 0.9403 1205416 Maybridge3_002717 OC(=O)c1ccccc1C(=O)Nc2cc(n[nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L12 compound treatment 0.325 0.0144 1.16 0.35 0.0379 3.44 3.2531 0.8964 2076472 Maybridge3_002718 COC(=O)c1sc(cc1NC(=O)c2ccc3nsnc3c2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L13 compound treatment 0.33 0.0194 1.57 0.321 0.00888 0.81 1.6764 0.9523 1429983 Maybridge3_002719 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NCC3CC3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L14 compound treatment 0.323 0.0124 1.0 0.33 0.0179 1.62 1.8555 0.9731 2076473 Maybridge3_002720 COc1ccc(cc1)C(=O)CSc2nnc(O)n2C(C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L15 compound treatment 0.322 0.0114 0.92 0.322 0.00988 0.9 1.2851 0.9999 2076474 Maybridge3_002721 Cn1cncc1CC2COC(=O)C2C(O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L16 compound treatment 0.324 0.0134 1.08 0.325 0.0129 1.17 1.5915 0.9993 2076475 Maybridge3_002722 O=C(c1cccnc1Oc2ccccc2)n3ccc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L17 compound treatment 0.333 0.0224 1.81 0.329 0.0169 1.53 2.3607 0.9966 1263872 Maybridge3_002723 Cc1noc(C)c1C(=O)N2CCCCC2c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L18 compound treatment 0.346 0.0354 2.85 0.355 0.0429 3.89 4.7698 0.9884 2076476 Maybridge3_002724 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3ccc4nccnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L19 compound treatment 0.337 0.0264 2.13 0.327 0.0149 1.35 2.4601 0.9759 1719415 Maybridge3_002725 CC(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L20 compound treatment 0.354 0.0434 3.5 0.332 0.0199 1.8 3.749 0.9526 2076477 Maybridge3_002726 COc1ccc(cc1)c2csc(COC(=O)C(C)(C)C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L21 compound treatment 0.322 0.0114 0.92 0.323 0.0109 0.99 1.3493 0.9994 1263678 Maybridge3_002727 Nc1nc2CCCCc2c(c1C#N)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L22 compound treatment 0.326 0.0154 1.24 0.324 0.0119 1.08 1.6412 0.9975 2076478 Maybridge3_002728 O=C(NC1CCN(Cc2ccccc2)CC1)C3CN(Cc4ccco4)C(=O)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L23 mock treatment 0.314 0.00344 0.28 0.315 0.00288 0.26 0.3803 0.9996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 L24 positive control 0.09 -0.221 -17.76 0.097 -0.215 -19.53 -26.3668 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M01 compound treatment 0.336 0.0254 2.05 0.328 0.0159 1.44 2.4674 0.9852 1407350 Maybridge3_002729 Cc1c(cnn1c2ccc(F)cc2)C(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M02 compound treatment 0.322 0.0114 0.92 0.333 0.0209 1.89 1.9911 0.9451 1505029 Maybridge3_002730 Nc1nc2CCCCc2c(c1C#N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M03 compound treatment 0.336 0.0254 2.05 0.331 0.0189 1.71 2.6599 0.9961 1145830 Maybridge3_002731 CCOC(=O)C1CCN(CC1)C(=O)c2cc3c(C)cc(C)cc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M04 compound treatment 0.323 0.0124 1.0 0.331 0.0189 1.71 1.9197 0.9673 1213047 Maybridge3_002732 Fc1ccc(CSc2ncnc3n(ncc23)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M05 compound treatment 0.326 0.0154 1.24 0.355 0.0429 3.89 3.631 0.8887 1397820 Maybridge3_002733 CCOC(=O)C1CCCN(C1)C(=O)c2csc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M06 compound treatment 0.329 0.0184 1.48 0.338 0.0259 2.35 2.7106 0.9755 2076479 Maybridge3_002734 O=C(NC1Cc2ccccc2C1)c3nnc(o3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M07 compound treatment 0.321 0.0104 0.84 0.323 0.0109 0.99 1.2923 0.9968 1236419 Maybridge3_002735 O=S(=O)(N1CCC2(CC1)OCCO2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M08 compound treatment 0.318 0.00744 0.6 0.326 0.0139 1.26 1.3141 0.9422 1202543 Maybridge3_002736 O=C(NCc1ccncc1)c2ccc(cc2)n3cccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M09 compound treatment 0.319 0.00844 0.68 0.326 0.0139 1.26 1.371 0.9581 1415125 Maybridge3_002737 Cc1ccc2oc(=O)n(CCC(=O)O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M10 compound treatment 0.322 0.0114 0.92 0.332 0.0199 1.8 1.9269 0.9513 1500247 Maybridge3_002738 CC(C)N(Cc1ccccc1)C(=O)c2cnn(c2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M11 compound treatment 0.308 -0.00256 -0.21 0.337 0.0249 2.26 1.4507 0.6398 1432016 Maybridge3_002739 O=S(=O)(Nc1ccccc1N2CCOCC2)c3ccc4CCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M12 compound treatment 0.326 0.0154 1.24 0.34 0.0279 2.53 2.6682 0.9465 2076480 Maybridge3_002740 CN(C1CCCCC1)C(=O)c2c(C)onc2c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M13 compound treatment 0.339 0.0284 2.29 0.32 0.00788 0.71 2.1247 0.8857 1331111 Maybridge3_002741 OC(=O)C1CCN(CC1)C(=O)c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M14 compound treatment 0.311 4.37E-4 0.04 0.324 0.0119 1.08 0.7871 0.7298 2076481 Maybridge3_002742 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M15 compound treatment 0.324 0.0134 1.08 0.322 0.00988 0.9 1.399 0.9956 2076482 Maybridge3_002743 CC(C)N(Cc1ccccc1)C(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M16 compound treatment 0.318 0.00744 0.6 0.361 0.0489 4.44 3.5605 0.7954 1625093 Maybridge3_002744 CCc1cc(C(=O)c2ccc(OC)cc2)c(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M17 compound treatment 0.335 0.0244 1.97 0.315 0.00288 0.26 1.576 0.7939 1137083 Maybridge3_002745 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M18 compound treatment 0.314 0.00344 0.28 0.323 0.0109 0.99 0.8937 0.8718 1615772 Maybridge3_002746 OC(=O)CSCC(=O)Nc1nnc(s1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M19 compound treatment 0.341 0.0304 2.45 0.334 0.0219 1.99 3.1372 0.9945 1256404 Maybridge3_002747 Clc1ccc2c(OCC(=O)c3ccccc3)ncnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M20 compound treatment 0.332 0.0214 1.73 0.364 0.0519 4.71 4.5503 0.9073 1707114 Maybridge3_002748 Oc1ccccc1C(=O)Nc2ccc(NC(=O)c3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M21 compound treatment 0.316 0.00544 0.44 0.325 0.0129 1.17 1.136 0.9102 1592139 Maybridge3_002749 NC(=O)c1sc2nnc(c3ccccc3)c(c4ccccc4)c2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M22 compound treatment 0.319 0.00844 0.68 0.343 0.0309 2.8 2.4622 0.8538 1538692 Maybridge3_002750 Cc1nc(Nc2ccccc2)sc1C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M23 mock treatment 0.305 -0.00556 -0.45 0.31 -0.00212 -0.19 -0.4531 -0.9291 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 M24 positive control 0.091 -0.22 -17.68 0.097 -0.215 -19.53 -26.3099 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N01 compound treatment 0.35 0.0394 3.18 0.336 0.0239 2.17 3.778 0.9826 2076483 Maybridge3_002751 OC(=O)CCCC(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N02 compound treatment 0.333 0.0224 1.81 0.352 0.0399 3.62 3.837 0.9485 2076484 Maybridge3_002752 Cc1c(sc2ccc(Cl)cc12)C(=O)CSc3nnc(O)n3c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N03 compound treatment 0.346 0.0354 2.85 0.328 0.0159 1.44 3.0368 0.9499 1288829 Maybridge3_002753 Cc1nnsc1C(=O)Nc2ccccc2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N04 compound treatment 0.322 0.0114 0.92 0.323 0.0109 0.99 1.3493 0.9994 1045516 Maybridge3_002754 O=S(=O)(Nc1cccc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N05 compound treatment 0.322 0.0114 0.92 0.334 0.0219 1.99 2.0553 0.939 1279312 Maybridge3_002755 N#CCCn1cccc1CN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N06 compound treatment 0.332 0.0214 1.73 0.339 0.0269 2.44 2.9456 0.9857 1178385 Maybridge3_002756 CN(CCc1ccccn1)C(=O)c2c(C)onc2c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N07 compound treatment 0.321 0.0104 0.84 0.326 0.0139 1.26 1.4849 0.9807 2076485 Maybridge3_002757 FC(F)(F)c1ccc(NC(=O)c2cccnc2Oc3ccc(Cl)cc3)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N08 compound treatment 0.329 0.0184 1.48 0.33 0.0179 1.62 2.1972 0.999 2076486 Maybridge3_002758 COC(=O)c1ccc(COc2ccc(NC(=O)C)cc2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N09 compound treatment 0.332 0.0214 1.73 0.322 0.00988 0.9 1.8545 0.9534 2076487 Maybridge3_002759 CC(c1ccccc1)n2c(O)nnc2SCC(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N10 compound treatment 0.331 0.0204 1.65 0.354 0.0419 3.8 3.8515 0.9298 2076488 Maybridge3_002760 O=C(Nc1ccc(cc1)N2CCCCC2)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N11 compound treatment 0.319 0.00844 0.68 0.323 0.0109 0.99 1.1785 0.9834 1358107 Maybridge3_002761 CC(C)(CC(=O)O)CC(=O)Nc1cc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N12 compound treatment 0.345 0.0344 2.77 0.337 0.0249 2.26 3.5575 0.9948 2076489 Maybridge3_002762 COC(=O)c1sc(cc1NC(=O)c2cc(C)nn2C)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N13 compound treatment 0.33 0.0194 1.57 0.35 0.0379 3.44 3.5378 0.9365 2076490 Maybridge3_002763 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NCc3ccncc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N14 compound treatment 0.328 0.0174 1.4 0.334 0.0219 1.99 2.397 0.9856 2076491 Maybridge3_002764 Cc1ccc(Oc2ncccc2NC(=O)CCCC(=O)O)c3CCCc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N15 compound treatment 0.356 0.0454 3.66 0.323 0.0109 0.99 3.2853 0.8669 1501370 Maybridge3_002765 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N16 compound treatment 0.324 0.0134 1.08 0.329 0.0169 1.53 1.8483 0.9855 2076492 Maybridge3_002766 Cc1cc2c(NC(=O)CSCC(=O)O)cccc2nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N17 compound treatment 0.328 0.0174 1.4 0.33 0.0179 1.62 2.1402 0.9974 1364557 Maybridge3_002767 Cc1noc(C)c1C(=O)Nc2nc3ccc(Cl)cc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N18 compound treatment 0.318 0.00744 0.6 0.336 0.0239 2.17 1.9559 0.8699 2076493 Maybridge3_002768 Clc1ccc(CCNC(=O)c2ccc3nccnc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N19 compound treatment 0.326 0.0154 1.24 0.322 0.00988 0.9 1.5129 0.9871 1484947 Maybridge3_002769 CC(=O)Nc1ccc(NC(=O)c2ccco2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N20 compound treatment 0.355 0.0444 3.58 0.328 0.0159 1.44 3.5492 0.9201 2076494 Maybridge3_002770 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N21 compound treatment 0.317 0.00644 0.52 0.318 0.00588 0.53 0.7436 0.9999 2076495 Maybridge3_002771 Oc1nc2CCCCc2c(c3cccs3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N22 compound treatment 0.311 4.37E-4 0.04 0.322 0.00988 0.9 0.6587 0.7343 2076496 Maybridge3_002772 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N23 mock treatment 0.313 0.00244 0.2 0.313 8.75E-4 0.08 0.195 0.9207 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 N24 positive control 0.09 -0.221 -17.76 0.095 -0.217 -19.71 -26.4952 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O01 compound treatment 0.341 0.0304 2.45 0.345 0.0329 2.98 3.8432 0.9952 1307178 Maybridge3_002773 CC(=O)Nc1ccc(cc1)c2cn3CCSc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O02 compound treatment 0.333 0.0224 1.81 0.39 0.0779 7.07 6.276 0.8602 1660562 Maybridge3_002774 C=CCn1c(=S)sc2c(Sc3nc4ccccc4[nH]3)ncnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O03 compound treatment 0.34 0.0294 2.37 0.333 0.0209 1.89 3.0161 0.9938 1658618 Maybridge3_002775 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCC(CC3)N4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O04 compound treatment 0.329 0.0184 1.48 0.346 0.0339 3.07 3.2241 0.9442 1728716 Maybridge3_002776 Cc1nn(c2ccccc2)c3[nH]c(=O)c(C#N)c(c4ccccc4)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O05 compound treatment 0.331 0.0204 1.65 0.337 0.0249 2.26 2.7603 0.9879 1192628 Maybridge3_002777 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(OC)c(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O06 compound treatment 0.346 0.0354 2.85 0.348 0.0359 3.26 4.3205 0.9978 1528426 Maybridge3_002778 CC1CN(Cc2ccccc2)CCN1C(=O)c3csc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O07 compound treatment 0.33 0.0194 1.57 0.33 0.0179 1.62 2.2541 0.9998 1608139 Maybridge3_002779 O=S(=O)(N1CCC2(CC1)OCCO2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O08 compound treatment 0.33 0.0194 1.57 0.342 0.0299 2.71 3.0243 0.9659 1490075 Maybridge3_002780 O=C(N1CCc2ccccc2C1)c3ccc(cc3)n4cccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O09 compound treatment 0.328 0.0174 1.4 0.334 0.0219 1.99 2.397 0.9856 1191348 Maybridge3_002781 Cc1cccc(NC(=O)c2cccs2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O10 compound treatment 0.325 0.0144 1.16 0.332 0.0199 1.8 2.0978 0.9774 2076497 Maybridge3_002782 CC(C)N(Cc1ccccc1)C(=O)c2cccc(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O11 compound treatment 0.349 0.0384 3.1 0.328 0.0159 1.44 3.2076 0.9395 2076498 Maybridge3_002783 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2ccccc2N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O12 compound treatment 0.362 0.0514 4.14 0.332 0.0199 1.8 4.2046 0.9306 2076499 Maybridge3_002784 CN(C1CCCCC1)C(=O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O13 compound treatment 0.328 0.0174 1.4 0.326 0.0139 1.26 1.8835 0.9985 1249583 Maybridge3_002785 OC(=O)C1CCN(CC1)C(=O)c2cc(F)cc3COCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O14 compound treatment 0.325 0.0144 1.16 0.328 0.0159 1.44 1.841 0.9943 2076500 Maybridge3_002786 Oc1nnc(SCC(=O)Nc2ccccc2)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O15 compound treatment 0.338 0.0274 2.21 0.331 0.0189 1.71 2.7738 0.9921 2076501 Maybridge3_002787 CC(C)N(Cc1ccccc1)C(=O)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O16 compound treatment 0.329 0.0184 1.48 0.357 0.0449 4.07 3.9302 0.9065 1478561 Maybridge3_002788 CCOC(=O)N1CCc2c(C(=O)c3ccc(OC)cc3)c(N)sc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O17 compound treatment 0.325 0.0144 1.16 0.332 0.0199 1.8 2.0978 0.9774 1380598 Maybridge3_002789 O=C1N(C(=O)C2=C1SCCS2)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O18 compound treatment 0.335 0.0244 1.97 0.333 0.0209 1.89 2.7314 0.9998 1733710 Maybridge3_002790 O=S(=O)(Nc1nnc(s1)C2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O19 compound treatment 0.323 0.0124 1.0 0.334 0.0219 1.99 2.1123 0.9498 1485477 Maybridge3_002791 OC(COc1ncnc2cc(Cl)ccc12)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O20 compound treatment 0.336 0.0254 2.05 0.333 0.0209 1.89 2.7883 0.9992 2076502 Maybridge3_002792 Cc1nnsc1c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O21 compound treatment 0.35 0.0394 3.18 0.349 0.0369 3.35 4.6124 0.9997 2076503 Maybridge3_002793 Cc1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O22 compound treatment 0.332 0.0214 1.73 0.334 0.0219 1.99 2.6247 0.9976 1403565 Maybridge3_002794 CN(C1CCCCC1)S(=O)(=O)c2c(C)noc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O23 mock treatment 0.321 0.0104 0.84 0.321 0.00888 0.81 1.164 0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 O24 positive control 0.09 -0.221 -17.76 0.097 -0.215 -19.53 -26.3668 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P01 compound treatment 0.33 0.0194 1.57 0.332 0.0199 1.8 2.3825 0.9975 2076504 Maybridge3_002795 OC(=O)CSCC(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P02 compound treatment 0.321 0.0104 0.84 0.329 0.0169 1.53 1.6774 0.9601 2076505 Maybridge3_002796 Oc1nnc(SCC(=O)c2ccc(F)cc2)n1C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P03 compound treatment 0.324 0.0134 1.08 0.321 0.00888 0.81 1.3348 0.9894 1191677 Maybridge3_002797 Cc1cc(no1)C(=O)Nc2ccccc2N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P04 compound treatment 0.324 0.0134 1.08 0.322 0.00988 0.9 1.399 0.9956 1370774 Maybridge3_002798 O=C(Nc1ccccc1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P05 compound treatment 0.331 0.0204 1.65 0.331 0.0189 1.71 2.3752 0.9998 2076506 Maybridge3_002799 CC(=O)Nc1cccc(OCCCN2CCS(=O)(=O)CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P06 compound treatment 0.33 0.0194 1.57 0.331 0.0189 1.71 2.3183 0.999 1595192 Maybridge3_002800 CN(CCc1ccccn1)S(=O)(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P07 compound treatment 0.318 0.00744 0.6 0.32 0.00788 0.71 0.929 0.9961 2076507 Maybridge3_002801 OC(=O)c1ccccc1C(=O)Nc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P08 compound treatment 0.323 0.0124 1.0 0.326 0.0139 1.26 1.5988 0.9936 2076508 Maybridge3_002802 COC(=O)c1ccc(cc1)c2cn3cccnc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P09 compound treatment 0.333 0.0224 1.81 0.321 0.00888 0.81 1.8473 0.9338 2076509 Maybridge3_002803 Oc1nnc(SCC(=O)Nc2ccccc2)n1C3Cc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P10 compound treatment 0.464 0.153 12.36 0.355 0.0429 3.89 11.4888 0.8869 2076510 Maybridge3_002804 Clc1ccc2[nH]c(cc2c1)C(=O)NCc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P11 compound treatment 0.323 0.0124 1.0 0.322 0.00988 0.9 1.342 0.9985 1653704 Maybridge3_002805 OC(=O)CCCC(=O)Nc1cc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P12 compound treatment 0.321 0.0104 0.84 0.332 0.0199 1.8 1.87 0.9396 2076511 Maybridge3_002806 C1SC(CC12Nc3ccccc3S2)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P13 compound treatment 0.325 0.0144 1.16 0.346 0.0339 3.07 2.9964 0.9115 1230307 Maybridge3_002807 Clc1ccc(OCC(=O)Nc2ccc3OCCOc3c2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P14 compound treatment 0.328 0.0174 1.4 0.329 0.0169 1.53 2.076 0.9991 2076512 Maybridge3_002808 Cc1ccc(Oc2ncccc2NC(=O)c3ccco3)c4CCCc41 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P15 compound treatment 0.318 0.00744 0.6 0.323 0.0109 0.99 1.1215 0.9713 1148749 Maybridge3_002809 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P16 compound treatment 0.299 -0.0116 -0.93 0.317 0.00488 0.44 -0.3455 -0.3351 2076513 Maybridge3_002810 Cc1cc2c(NC(=O)c3ccccc3C(=O)O)cccc2nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P17 compound treatment 0.325 0.0144 1.16 0.325 0.0129 1.17 1.6485 1.0 1303417 Maybridge3_002811 O=C(Nc1ccc2[nH]ccc2c1)c3cccnc3Sc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P18 compound treatment 0.318 0.00744 0.6 0.315 0.00288 0.26 0.608 0.9307 1760441 Maybridge3_002812 O=C(NCc1cccs1)c2ccc3nccnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P19 compound treatment 0.369 0.0584 4.71 0.323 0.0109 0.99 4.0255 0.8372 1120072 Maybridge3_002813 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(s2)c3csc(C)n3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P20 compound treatment 0.324 0.0134 1.08 0.322 0.00988 0.9 1.399 0.9956 1323497 Maybridge3_002814 O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P21 compound treatment 0.343 0.0324 2.61 0.327 0.0149 1.35 2.8018 0.9528 1359634 Maybridge3_002815 C=CCn1c(=S)sc2c(ncnc12)C(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P22 compound treatment 0.323 0.0124 1.0 0.323 0.0109 0.99 1.4062 1.0 1548098 Maybridge3_002816 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P23 mock treatment 0.314 0.00344 0.28 0.315 0.00288 0.26 0.3803 0.9996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1438 P24 positive control 0.092 -0.219 -17.6 0.098 -0.214 -19.44 -26.1888 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A01 compound treatment 0.314 8.12E-4 0.07 0.319 -0.00506 -0.46 -0.2787 -0.6004 2076514 Maybridge3_002817 CC1CC(=O)Nc2ccccc2N1C(=O)c3cc(Cl)sc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A02 compound treatment 0.347 0.0338 2.72 0.304 -0.0201 -1.82 0.6376 0.1946 2076515 Maybridge3_002818 COc1ccc(NCc2ccc[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A03 compound treatment 0.308 -0.00519 -0.42 0.313 -0.0111 -1.0 -1.0054 -0.9245 2076516 Maybridge3_002819 FC(F)(F)c1ccc(cc1)c2nnc(o2)c3ccc4nccnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A04 compound treatment 0.307 -0.00619 -0.5 0.313 -0.0111 -1.0 -1.0624 -0.9477 2076517 Maybridge3_002820 CC(C)(C)c1ccc(NC(=O)c2ccsc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A05 compound treatment 0.31 -0.00319 -0.26 0.311 -0.0131 -1.19 -1.0199 -0.8407 1249645 Maybridge3_002821 CCC1c2c(Oc3c1c(=O)oc4ccccc34)nc(C)[nH]c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A06 compound treatment 0.319 0.00581 0.47 0.307 -0.0171 -1.55 -0.7642 -0.4723 1289349 Maybridge3_002822 Clc1cc(c(Cl)s1)S(=O)(=O)NCC2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A07 compound treatment 0.306 -0.00719 -0.58 0.311 -0.0131 -1.19 -1.2477 -0.9456 2076518 Maybridge3_002823 O=C1N(Cc2ccc3nsnc3c2)S(=O)(=O)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A08 compound treatment 0.305 -0.00819 -0.66 0.31 -0.0141 -1.28 -1.3688 -0.9528 2076519 Maybridge3_002824 COc1ccc(cc1)c2nnsc2NC(=O)c3ccccc3CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A09 compound treatment 0.302 -0.0112 -0.9 0.313 -0.0111 -1.0 -1.3471 -0.9985 2076520 Maybridge3_002825 COc1ccccc1CC(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A10 compound treatment 0.311 -0.00219 -0.18 0.309 -0.0151 -1.37 -1.0913 -0.7917 2076521 Maybridge3_002826 OC(=O)COCc1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A11 compound treatment 0.306 -0.00719 -0.58 0.314 -0.0101 -0.91 -1.0551 -0.9758 1113215 Maybridge3_002827 O=C1Nc2ccccc2C1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A12 compound treatment 0.32 0.00681 0.55 0.316 -0.00806 -0.73 -0.1296 -0.1417 1054438 Maybridge3_002828 OC(=O)c1cccc(CC=C)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A13 compound treatment 0.31 -0.00319 -0.26 0.325 9.38E-4 0.09 -0.1213 -0.4487 2076522 Maybridge3_002829 COc1cccc(c1)C(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A14 compound treatment 0.305 -0.00819 -0.66 0.31 -0.0141 -1.28 -1.3688 -0.9528 2076523 Maybridge3_002830 CCOC(=O)c1nnc(o1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A15 compound treatment 0.307 -0.00619 -0.5 0.312 -0.0121 -1.09 -1.1266 -0.9365 2076524 Maybridge3_002831 Cn1nc(cc1NC(=O)C2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A16 compound treatment 0.305 -0.00819 -0.66 0.313 -0.0111 -1.0 -1.1763 -0.9792 2076525 Maybridge3_002832 CCCSc1ncccc1C(=O)Nc2cccc3nonc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A17 compound treatment 0.31 -0.00319 -0.26 0.427 0.103 9.34 6.4256 0.6874 2076526 Maybridge3_002833 O=c1[nH]c(cc(c2ccco2)c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A18 compound treatment 0.324 0.0108 0.87 0.328 0.00394 0.36 0.8684 0.9227 2076527 Maybridge3_002834 Clc1ccc(cc1)C2=NOC(C2)C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A19 compound treatment 0.311 -0.00219 -0.18 0.313 -0.0111 -1.0 -0.8346 -0.8186 2076528 Maybridge3_002835 OC(=O)CCc1ccc2OCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A20 compound treatment 0.309 -0.00419 -0.34 0.315 -0.00906 -0.82 -0.8201 -0.9225 2076529 Maybridge3_002836 C=CCSc1nnc2NCCCn12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A21 compound treatment 0.304 -0.00919 -0.74 0.333 0.00894 0.81 0.0505 0.046 2076530 Maybridge3_002837 Oc1ccccc1C(=O)NC(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A22 compound treatment 0.305 -0.00819 -0.66 0.334 0.00994 0.9 0.1716 0.1536 2076531 Maybridge3_002838 C/C(=C\1/CCOC1=O)/Nc2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A23 mock treatment 0.301 -0.0122 -0.98 0.308 -0.0161 -1.46 -1.7249 -0.9814 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 A24 positive control 0.084 -0.229 -18.46 0.086 -0.238 -21.61 -28.3302 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B01 compound treatment 0.327 0.0138 1.11 0.332 0.00794 0.72 1.296 0.9779 2076532 Maybridge3_002839 CSc1ncnc2n(Cc3ccccc3)nnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B02 compound treatment 0.329 0.0158 1.27 0.328 0.00394 0.36 1.1531 0.8719 1077132 Maybridge3_002840 COc1ccc2c(OC)cccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B03 compound treatment 0.334 0.0208 1.68 0.329 0.00494 0.45 1.502 0.8658 2076533 Maybridge3_002841 Clc1ccc(COc2ccncc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B04 compound treatment 0.325 0.0118 0.95 0.326 0.00194 0.18 0.797 0.8239 1396844 Maybridge3_002842 CCS(=O)CC(=O)Nc1c(oc2ccccc2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B05 compound treatment 0.333 0.0198 1.6 0.329 0.00494 0.45 1.4451 0.872 2076534 Maybridge3_002843 CSc1nnc(c2sc3nc(C)cc(C)c3c2N)n1Cc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B06 compound treatment 0.321 0.00781 0.63 0.315 -0.00906 -0.82 -0.1368 -0.1321 2076535 Maybridge3_002844 Fc1ccc(cc1)C(=O)/C=C/OC(=O)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B07 compound treatment 0.322 0.00881 0.71 0.346 0.0219 1.99 1.9099 0.9034 2076536 Maybridge3_002845 Nc1nc(ncc1C#N)N2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B08 compound treatment 0.259 -0.0542 -4.36 0.339 0.0149 1.36 -2.1267 -0.4654 2076537 Maybridge3_002846 CN(C)c1ccc(/C=C/c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B09 compound treatment 0.318 0.00481 0.39 0.317 -0.00706 -0.64 -0.1793 -0.2393 2076538 Maybridge3_002847 CCOC(=O)CSc1nc(NC)c2c3CCCCc3sc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B10 compound treatment 0.324 0.0108 0.87 0.324 -6.25E-5 -0.01 0.6117 0.7025 2076539 Maybridge3_002848 CC(=O)Oc1c(sc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B11 compound treatment 0.319 0.00581 0.47 0.322 -0.00206 -0.19 0.1986 0.3939 2076540 Maybridge3_002849 COc1cccc(Nc2ncc(C#N)c(N)n2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B12 compound treatment 0.33 0.0168 1.35 0.325 9.38E-4 0.09 1.0175 0.7501 2076541 Maybridge3_002850 CC1(C)OC2OC(CO)C(O)C(O)C2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B13 compound treatment 0.32 0.00681 0.55 0.328 0.00394 0.36 0.6406 0.9785 2076542 Maybridge3_002851 Nc1ncc(cc1C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B14 compound treatment 0.324 0.0108 0.87 0.33 0.00594 0.54 0.9968 0.9734 2076543 Maybridge3_002852 CCSC(=O)NCc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B15 compound treatment 0.332 0.0188 1.51 0.181 -0.143 -12.99 -8.1113 -0.6204 2076544 Maybridge3_002853 CCOC(=O)Cn1sc2nc(C)cc(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B16 compound treatment 0.334 0.0208 1.68 0.322 -0.00206 -0.19 1.0527 0.6242 1548418 Maybridge3_002854 Fc1ccccc1CC(=O)NCCc2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B17 compound treatment 0.341 0.0278 2.24 0.331 0.00694 0.63 2.029 0.8721 2076545 Maybridge3_002855 Cc1ccccc1n2cc(nc2SCC(=O)N)c3ccc(Br)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B18 compound treatment 0.317 0.00381 0.31 0.386 0.0619 5.62 4.1926 0.7446 1022389 Maybridge3_002856 CN(C)c1ccc(cc1)C(=S)c2ccc(cc2)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B19 compound treatment 0.32 0.00681 0.55 0.446 0.122 11.07 8.2145 0.7412 2076546 Maybridge3_002857 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3nnc(s3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B20 compound treatment 0.342 0.0288 2.32 0.327 0.00294 0.27 1.8292 0.7832 1291803 Maybridge3_002858 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccoc3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B21 compound treatment 0.322 0.00881 0.71 0.327 0.00294 0.27 0.6903 0.9106 2076547 Maybridge3_002859 Nc1nc(cc(c2cccs2)c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B22 compound treatment 0.321 0.00781 0.63 0.328 0.00394 0.36 0.6976 0.9641 1707826 Maybridge3_002860 OCC(CO)NC(=O)OCC1c2ccccc2-c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B23 mock treatment 0.316 0.00281 0.23 0.325 9.38E-4 0.09 0.2203 0.9106 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 B24 positive control 0.084 -0.229 -18.46 0.084 -0.24 -21.79 -28.4586 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C01 compound treatment 0.32 0.00681 0.55 0.325 9.38E-4 0.09 0.4481 0.8071 2076548 Maybridge3_002861 Cc1nnsc1C(=O)NCc2ccc(cc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C02 compound treatment 0.337 0.0238 1.92 0.329 0.00494 0.45 1.6728 0.8495 2076549 Maybridge3_002862 COc1ccc(cc1)N(Cc2ccccn2)C(=O)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C03 compound treatment 0.326 0.0128 1.03 0.31 -0.0141 -1.28 -0.173 -0.1054 2076550 Maybridge3_002863 CCOC(=O)c1cnn(C(=O)c2cccc3ccccc23)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C04 compound treatment 0.331 0.0178 1.43 0.327 0.00294 0.27 1.2028 0.8244 2076551 Maybridge3_002864 O=C(NCc1ccco1)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C05 compound treatment 0.319 0.00581 0.47 0.319 -0.00506 -0.46 0.006 0.0092 2076552 Maybridge3_002865 C=CCn1c(=S)sc2c(ncnc12)N3CCN(CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C06 compound treatment 0.323 0.00981 0.79 0.324 -6.25E-5 -0.01 0.5547 0.702 1509965 Maybridge3_002866 O=S(=O)(NCC1COc2ccccc2O1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C07 compound treatment 0.323 0.00981 0.79 0.322 -0.00206 -0.19 0.4264 0.525 2076553 Maybridge3_002867 Cc1cc(CN2C(=O)c3ccccc3S2(=O)=O)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C08 compound treatment 0.315 0.00181 0.15 0.328 0.00394 0.36 0.3559 0.922 2076554 Maybridge3_002868 CCOC(=O)c1cn2nc(Oc3ccccc3)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C09 compound treatment 0.314 8.12E-4 0.07 0.338 0.0139 1.27 0.9408 0.7427 2076555 Maybridge3_002869 Oc1ccccc1C(=O)NC(=O)c2sc3ccccc3c2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C10 compound treatment 0.324 0.0108 0.87 0.347 0.0229 2.08 2.0879 0.9252 2076556 Maybridge3_002870 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C11 compound treatment 0.318 0.00481 0.39 0.353 0.0289 2.63 2.1314 0.8027 2076557 Maybridge3_002871 c1snnc1c2ccc(cc2)c3nc(cs3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C12 compound treatment 0.326 0.0128 1.03 0.33 0.00594 0.54 1.1107 0.9541 2076558 Maybridge3_002872 Clc1ccc(cc1)n2ncc(n2)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C13 compound treatment 0.326 0.0128 1.03 0.341 0.0169 1.54 1.8167 0.9812 1294098 Maybridge3_002873 Cc1onc(c1C(=O)N2CCCc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C14 compound treatment 0.326 0.0128 1.03 0.318 -0.00606 -0.55 0.3404 0.2911 2076559 Maybridge3_002874 N(c1nnc(o1)c2cccc3ccccc23)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C15 compound treatment 0.318 0.00481 0.39 0.319 -0.00506 -0.46 -0.0509 -0.0847 2076560 Maybridge3_002875 Cn1nc(cc1NC(=O)CCCC(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C16 compound treatment 0.325 0.0118 0.95 0.332 0.00794 0.72 1.1821 0.9906 2076561 Maybridge3_002876 CCCSc1ncccc1C(=O)Nc2cc(C)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C17 compound treatment 0.315 0.00181 0.15 0.331 0.00694 0.63 0.5485 0.8485 1213370 Maybridge3_002877 O=c1[nH]c(cc(c2ccco2)c1C#N)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C18 compound treatment 0.318 0.00481 0.39 0.329 0.00494 0.45 0.5909 0.9974 2076562 Maybridge3_002878 O=C(OCC1CC(=NO1)c2ccccc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C19 compound treatment 0.335 0.0218 1.76 0.318 -0.00606 -0.55 0.8529 0.4634 2076563 Maybridge3_002879 C/C(=N\O)/C(C)(C)NCCc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C20 compound treatment 0.317 0.00381 0.31 0.328 0.00394 0.36 0.4698 0.9971 2076564 Maybridge3_002880 CCOC(=O)CSc1nnc(c2ccncc2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C21 compound treatment 0.313 -1.88E-4 -0.02 0.321 -0.00306 -0.28 -0.2072 -0.7444 2076565 Maybridge3_002881 CCC1(CCCCNC1=O)c2cccc(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C22 compound treatment 0.321 0.00781 0.63 0.339 0.0149 1.36 1.4036 0.939 2076566 Maybridge3_002882 C/C(=C\1/CCOC1=O)/Nc2ccccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C23 mock treatment 0.311 -0.00219 -0.18 0.319 -0.00506 -0.46 -0.4495 -0.9134 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 C24 positive control 0.088 -0.225 -18.13 0.088 -0.236 -21.43 -27.9741 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D01 compound treatment 0.33 0.0168 1.35 0.333 0.00894 0.81 1.531 0.97 2076567 Maybridge3_002883 S=c1[nH]cnc2n(Cc3ccccc3)nnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D02 compound treatment 0.345 0.0318 2.56 0.33 0.00594 0.54 2.1925 0.8375 2076568 Maybridge3_002884 O=C(NC1CCCCC1)SCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D03 compound treatment 0.319 0.00581 0.47 0.326 0.00194 0.18 0.4553 0.9106 2076569 Maybridge3_002885 CC(C)(C)OC(=O)N1C(COC1(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D04 compound treatment 0.326 0.0128 1.03 0.326 0.00194 0.18 0.8539 0.8159 1721183 Maybridge3_002886 Clc1ccc2C(=O)CC(Oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D05 compound treatment 0.322 0.00881 0.71 0.342 0.0179 1.63 1.6531 0.9307 2076570 Maybridge3_002887 CCOC(=O)c1nnn2c1nc(SCC=C)c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D06 compound treatment 0.32 0.00681 0.55 0.316 -0.00806 -0.73 -0.1296 -0.1417 1280047 Maybridge3_002888 CC1(C)Oc2cc(OCC(=O)Nc3ccccc3)ccc2C=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D07 compound treatment 0.329 0.0158 1.27 0.341 0.0169 1.54 1.9875 0.9956 2076571 Maybridge3_002889 C=CCC(C(=O)N1CCc2ccccc12)C(=O)N3CCc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D08 compound treatment 0.33 0.0168 1.35 0.326 0.00194 0.18 1.0817 0.7923 2076572 Maybridge3_002890 CC(C)(C)C(Cc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D09 compound treatment 0.329 0.0158 1.27 0.326 0.00194 0.18 1.0247 0.7972 2076573 Maybridge3_002891 Nc1c(cnn1c2ccccc2)c3nnc(SCc4ccc(Cl)cc4)o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D10 compound treatment 0.393 0.0798 6.43 0.332 0.00794 0.72 5.0541 0.7815 2076574 Maybridge3_002892 COC(=O)c1ccccc1S(=O)(=O)Cc2ccc(OC)c(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D11 compound treatment 0.321 0.00781 0.63 0.351 0.0269 2.45 2.1738 0.861 2076575 Maybridge3_002893 C=CCn1c2ccccc2c3nn4cnnc4nc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D12 compound treatment 0.321 0.00781 0.63 0.33 0.00594 0.54 0.8259 0.997 2076576 Maybridge3_002894 O=C(OCC#N)c1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D13 compound treatment 0.326 0.0128 1.03 0.33 0.00594 0.54 1.1107 0.9541 2076577 Maybridge3_002895 CCOC(=O)N1CCc2c(C1)sc3nc[nH]c(=O)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D14 compound treatment 0.317 0.00381 0.31 0.453 0.129 11.7 8.493 0.7254 2076578 Maybridge3_002896 O=C(NC1CCCCC1)Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D15 compound treatment 0.329 0.0158 1.27 0.301 -0.0231 -2.09 -0.5799 -0.2367 2076579 Maybridge3_002897 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D16 compound treatment 0.326 0.0128 1.03 0.314 -0.0101 -0.91 0.0837 0.0607 2076580 Maybridge3_002898 O=C(Oc1ccc(Oc2ccccc2)cc1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D17 compound treatment 0.331 0.0178 1.43 0.321 -0.00306 -0.28 0.8177 0.5597 2076581 Maybridge3_002899 O=C(CSc1ncnc2sc(cc12)c3ccccc3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D18 compound treatment 0.324 0.0108 0.87 0.322 -0.00206 -0.19 0.4833 0.5427 1261683 Maybridge3_002900 COc1ccc(cc1)C(O)(C2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D19 compound treatment 0.344 0.0308 2.48 0.332 0.00794 0.72 2.264 0.8762 2076582 Maybridge3_002901 OC(=O)CSc1nnc([nH]1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D20 compound treatment 0.336 0.0228 1.84 0.336 0.0119 1.08 2.0652 0.9683 1490238 Maybridge3_002902 Cc1ccc(Sc2ccccc2C(=O)O)c(c1)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D21 compound treatment 0.316 0.00281 0.23 0.333 0.00894 0.81 0.7338 0.8712 2076583 Maybridge3_002903 COc1ccc(cc1)c2cc(c3ccccc3)c4c(N)ncnc4n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D22 compound treatment 0.322 0.00881 0.71 0.33 0.00594 0.54 0.8829 0.9908 2076584 Maybridge3_002904 CC(=O)OC1CSSCC1OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D23 mock treatment 0.311 -0.00219 -0.18 0.321 -0.00306 -0.28 -0.3211 -0.9758 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 D24 positive control 0.088 -0.225 -18.13 0.088 -0.236 -21.43 -27.9741 -0.9966 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E01 compound treatment 0.327 0.0138 1.11 0.332 0.00794 0.72 1.296 0.9779 2076585 Maybridge3_002905 FC(F)(F)c1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E02 compound treatment 0.331 0.0178 1.43 0.327 0.00294 0.27 1.2028 0.8244 2076586 Maybridge3_002906 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E03 compound treatment 0.337 0.0238 1.92 0.326 0.00194 0.18 1.4803 0.7687 1731255 Maybridge3_002907 Cc1cc(on1)c2ccccc2C(=O)NC3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E04 compound treatment 0.327 0.0138 1.11 0.317 -0.00706 -0.64 0.3332 0.2595 2076587 Maybridge3_002908 Clc1ccc(CSc2nc(NS(=O)(=O)c3ccccc3)n[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E05 compound treatment 0.328 0.0148 1.19 0.328 0.00394 0.36 1.0962 0.8803 1589685 Maybridge3_002909 CN1CCN(CC1)c2nc(C)nc3n(c4ccccc4)c(=S)sc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E06 compound treatment 0.325 0.0118 0.95 0.33 0.00594 0.54 1.0537 0.9638 2076588 Maybridge3_002910 COc1ccc(NS(=O)(=O)c2ccc(Cl)s2)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E07 compound treatment 0.323 0.00981 0.79 0.344 0.0199 1.81 1.8384 0.931 2076589 Maybridge3_002911 Cc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E08 compound treatment 0.326 0.0128 1.03 0.348 0.0239 2.17 2.266 0.9421 2076590 Maybridge3_002912 Clc1ccc(cc1)c2nc3ccccc3[nH]c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E09 compound treatment 0.322 0.00881 0.71 0.341 0.0169 1.54 1.5889 0.9384 2076591 Maybridge3_002913 Cc1ccc(Oc2ncccc2C(=O)NC(=O)c3ccccc3O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E10 compound treatment 0.329 0.0158 1.27 0.338 0.0139 1.27 1.795 1.0 2076592 Maybridge3_002914 COc1cccc(Cc2nnc(o2)c3ccc4OCOc4c3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E11 compound treatment 0.321 0.00781 0.63 0.333 0.00894 0.81 1.0185 0.9921 2076593 Maybridge3_002915 CS(=O)(=O)c1ccc(cc1)c2csc(n2)c3ccc(cc3)c4csnn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E12 compound treatment 0.332 0.0188 1.51 0.338 0.0139 1.27 1.9658 0.996 2076594 Maybridge3_002916 Nc1nn(nc1C(=O)c2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E13 compound treatment 0.332 0.0188 1.51 0.346 0.0219 1.99 2.4793 0.9909 2076595 Maybridge3_002917 Cc1nc(sc1C(=O)N2CCCc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E14 compound treatment 0.316 0.00281 0.23 0.328 0.00394 0.36 0.4129 0.9758 2076596 Maybridge3_002918 C/C(=N\O)/C(C)(C)Nc1ccc2OCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E15 compound treatment 0.336 0.0228 1.84 0.336 0.0119 1.08 2.0652 0.9683 2076597 Maybridge3_002919 Cn1nc(cc1NC(=O)c2ccccc2C(=O)O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E16 compound treatment 0.322 0.00881 0.71 0.332 0.00794 0.72 1.0113 1.0 2076598 Maybridge3_002920 FC(F)(F)c1ccc(NS(=O)(=O)c2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E17 compound treatment 0.323 0.00981 0.79 0.367 0.0429 3.9 3.3147 0.8335 1509251 Maybridge3_002921 O=c1[nH]c(cc(c2ccco2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E18 compound treatment 0.322 0.00881 0.71 0.33 0.00594 0.54 0.8829 0.9908 2076599 Maybridge3_002922 O(c1ccccn1)c2cccc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E19 compound treatment 0.316 0.00281 0.23 0.321 -0.00306 -0.28 -0.0364 -0.1016 2076600 Maybridge3_002923 C/C(=N\O)/C(C)(C)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E20 compound treatment 0.312 -0.00119 -0.1 0.336 0.0119 1.08 0.6986 0.6422 2076601 Maybridge3_002924 CC1CCc2c(C#N)c(NC(=O)CSc3nccn3C)sc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E21 compound treatment 0.339 0.0258 2.08 0.337 0.0129 1.17 2.3002 0.9635 2076602 Maybridge3_002925 Cc1ccc(cc1)c2nc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E22 compound treatment 0.321 0.00781 0.63 0.339 0.0149 1.36 1.4036 0.939 2076603 Maybridge3_002926 C/C(=C\1/CCOC1=O)/Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E23 mock treatment 0.311 -0.00219 -0.18 0.32 -0.00406 -0.37 -0.3853 -0.9428 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 E24 positive control 0.09 -0.223 -17.97 0.091 -0.233 -21.16 -27.6676 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F01 compound treatment 0.329 0.0158 1.27 0.338 0.0139 1.27 1.795 1.0 2076604 Maybridge3_002927 FC(F)(F)c1cccc(Nc2ncnc3n(Cc4ccccc4)nnc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F02 compound treatment 0.332 0.0188 1.51 0.33 0.00594 0.54 1.4523 0.9032 2076605 Maybridge3_002928 CC(C)(C)NC(=O)Oc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F03 compound treatment 0.335 0.0218 1.76 0.328 0.00394 0.36 1.4948 0.8339 2076606 Maybridge3_002929 CC(C)CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F04 compound treatment 0.327 0.0138 1.11 0.322 -0.00206 -0.19 0.6541 0.5799 2076607 Maybridge3_002930 OC1C(Oc2ccccc2C1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F05 compound treatment 0.349 0.0358 2.88 0.343 0.0189 1.72 3.2547 0.9694 2076608 Maybridge3_002931 Clc1ccc(cc1)n2c(Cn3nnc4ccccc34)nnc2SCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F06 compound treatment 0.327 0.0138 1.11 0.322 -0.00206 -0.19 0.6541 0.5799 2076609 Maybridge3_002932 CC1=C(C#N)C(C2=C(N1)c3ccccc3C2=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F07 compound treatment 0.323 0.00981 0.79 0.352 0.0279 2.54 2.3519 0.8854 2076610 Maybridge3_002933 Clc1ccc(cc1)c2c(C#N)c(=O)[nH]c-3c2COc4ccccc43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F08 compound treatment 0.381 0.0678 5.46 0.335 0.0109 0.99 4.5633 0.8222 2076611 Maybridge3_002934 c1ccc(nc1)c2nccnc2c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F09 compound treatment 0.314 8.12E-4 0.07 0.333 0.00894 0.81 0.6199 0.7617 1607073 Maybridge3_002935 Cc1cc(NC(=O)CSc2nc3ccccc3[nH]2)n(n1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F10 compound treatment 0.349 0.0358 2.88 0.338 0.0139 1.27 2.9338 0.9316 1489868 Maybridge3_002936 COc1ccc(cc1OC)C(=O)CC(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F11 compound treatment 0.333 0.0198 1.6 0.331 0.00694 0.63 1.5734 0.9173 2076612 Maybridge3_002937 CC1=Nn2c(nnc2SC1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F12 compound treatment 0.327 0.0138 1.11 0.324 -6.25E-5 -0.01 0.7825 0.7035 1251199 Maybridge3_002938 O=c1cc(oc2ccc(cc12)c3nnn[nH]3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F13 compound treatment 0.316 0.00281 0.23 0.339 0.0149 1.36 1.1189 0.8139 1625565 Maybridge3_002939 Nc1sc(cc1C(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F14 compound treatment 0.32 0.00681 0.55 0.331 0.00694 0.63 0.8332 0.9976 1012288 Maybridge3_002940 NC(C1CCCCC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F15 compound treatment 0.33 0.0168 1.35 0.308 -0.0161 -1.46 -0.0737 -0.037 2076613 Maybridge3_002941 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F16 compound treatment 0.32 0.00681 0.55 0.327 0.00294 0.27 0.5765 0.9451 1228625 Maybridge3_002942 COc1cccc(OC)c1CCOC(=O)c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F17 compound treatment 0.347 0.0338 2.72 0.366 0.0419 3.81 4.6171 0.9865 2076614 Maybridge3_002943 Nc1c(sc2nsc(SCCN3CCOCC3)c12)C(=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F18 compound treatment 0.325 0.0118 0.95 0.333 0.00894 0.81 1.2463 0.9969 2076615 Maybridge3_002944 FC(F)(F)c1ccc(cc1)N2CCCCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F19 compound treatment 0.344 0.0308 2.48 0.332 0.00794 0.72 2.264 0.8762 2076616 Maybridge3_002945 NC(=O)CSc1nc(CN2c3ccccc3Sc4ccccc24)n[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F20 compound treatment 0.327 0.0138 1.11 0.334 0.00994 0.9 1.4243 0.9946 1601566 Maybridge3_002946 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)C3CCC3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F21 compound treatment 0.085 -0.228 -18.38 0.331 0.00694 0.63 -12.5479 -0.6825 2076617 Maybridge3_002947 COc1ccc(/C=C(\C#N)/c2cccc(Cl)c2)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F22 compound treatment 0.318 0.00481 0.39 0.32 -0.00406 -0.37 0.0133 0.0248 2076618 Maybridge3_002948 O=C(OC1CSSCC1OC(=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F23 mock treatment 0.314 8.12E-4 0.07 0.326 0.00194 0.18 0.1706 0.9093 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 F24 positive control 0.09 -0.223 -17.97 0.089 -0.235 -21.34 -27.796 -0.9964 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G01 compound treatment 0.329 0.0158 1.27 0.327 0.00294 0.27 1.0889 0.837 2076619 Maybridge3_002949 Cn1nc(cc1NC(=O)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G02 compound treatment 0.324 0.0108 0.87 0.325 9.38E-4 0.09 0.6758 0.7725 2076620 Maybridge3_002950 CCOC(=O)N1CCC(CC1)NC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G03 compound treatment 0.337 0.0238 1.92 0.32 -0.00406 -0.37 1.0952 0.5608 1336744 Maybridge3_002951 Cc1cc(on1)c2ccccc2C(=O)Nc3ccccc3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G04 compound treatment 0.329 0.0158 1.27 0.331 0.00694 0.63 1.3457 0.9473 2076621 Maybridge3_002952 Nc1nnc(o1)c2ccc3nsnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G05 compound treatment 0.325 0.0118 0.95 0.328 0.00394 0.36 0.9253 0.9106 1561126 Maybridge3_002953 Cc1nc(N2CCOCC2)c3sc(=S)n(c4ccccc4)c3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G06 compound treatment 0.321 0.00781 0.63 0.323 -0.00106 -0.1 0.3767 0.5918 2076622 Maybridge3_002954 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G07 compound treatment 0.32 0.00681 0.55 0.33 0.00594 0.54 0.769 1.0 2076623 Maybridge3_002955 COc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G08 compound treatment 0.313 -1.88E-4 -0.02 0.34 0.0159 1.45 1.0123 0.6997 2076624 Maybridge3_002956 Cc1ccc2cc(NC(=O)C3CN(Cc4ccco4)C(=O)C3)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G09 compound treatment 0.322 0.00881 0.71 0.345 0.0209 1.9 1.8457 0.9098 2076625 Maybridge3_002957 CCCc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G10 compound treatment 0.328 0.0148 1.19 0.337 0.0129 1.17 1.6738 1.0 2076626 Maybridge3_002958 COc1cccc(Cc2nnc(o2)c3snnc3C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G11 compound treatment 0.339 0.0258 2.08 0.343 0.0189 1.72 2.6853 0.9955 2076627 Maybridge3_002959 COC(=O)CNC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G12 compound treatment 0.321 0.00781 0.63 0.338 0.0139 1.27 1.3394 0.948 2076628 Maybridge3_002960 O=c1oc2ccccc2cc1c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G13 compound treatment 0.335 0.0218 1.76 0.339 0.0149 1.36 2.2008 0.9918 2076629 Maybridge3_002961 Cc1nn(nc1C(=O)N2CCCc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G14 compound treatment 0.322 0.00881 0.71 0.333 0.00894 0.81 1.0754 0.9978 2076630 Maybridge3_002962 O=C(Nc1ccc2OCCOc2c1)c3ccoc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G15 compound treatment 0.307 -0.00619 -0.5 0.333 0.00894 0.81 0.2213 0.2325 2076631 Maybridge3_002963 COc1ccc(NC(=O)c2scc(c2N)S(=O)(=O)C(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G16 compound treatment 0.33 0.0168 1.35 0.352 0.0279 2.54 2.7505 0.9568 2076632 Maybridge3_002964 Cc1nn(nc1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G17 compound treatment 0.325 0.0118 0.95 0.343 0.0189 1.72 1.8881 0.9611 1537696 Maybridge3_002965 CC1CCc2c(C1)sc3nc(SCC(=O)N)nc(NCc4ccccc4)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G18 compound treatment 0.317 0.00381 0.31 0.33 0.00594 0.54 0.5982 0.9644 1496557 Maybridge3_002966 O=C(NCc1ccco1)c2cc3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G19 compound treatment 0.318 0.00481 0.39 0.354 0.0299 2.72 2.1956 0.7999 2076633 Maybridge3_002967 Cc1nc(sc1C(=O)NC(=O)c2ccccc2O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G20 compound treatment 0.323 0.00981 0.79 0.347 0.0229 2.08 2.031 0.912 2076634 Maybridge3_002968 CC1CCc2c(C#N)c(NC(=O)CSc3nnc[nH]3)sc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G21 compound treatment 0.33 0.0168 1.35 0.334 0.00994 0.9 1.5952 0.9805 2076635 Maybridge3_002969 CC(=O)Nc1ccc(cc1)c2nc3ccccc3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G22 compound treatment 0.32 0.00681 0.55 0.327 0.00294 0.27 0.5765 0.9451 2076636 Maybridge3_002970 Cc1cc(NC(=O)CSc2nccn2C)n(n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G23 mock treatment 0.31 -0.00319 -0.26 0.32 -0.00406 -0.37 -0.4423 -0.9843 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 G24 positive control 0.092 -0.221 -17.81 0.095 -0.229 -20.79 -27.297 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H01 compound treatment 0.329 0.0158 1.27 0.337 0.0129 1.17 1.7308 0.9992 2076637 Maybridge3_002971 CCN(CC)c1ncnc2n(Cc3ccccc3)nnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H02 compound treatment 0.327 0.0138 1.11 0.327 0.00294 0.27 0.975 0.8525 2076638 Maybridge3_002972 CN1CCN(CC1)C(=O)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H03 compound treatment 0.327 0.0138 1.11 0.327 0.00294 0.27 0.975 0.8525 2076639 Maybridge3_002973 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NC2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H04 compound treatment 0.329 0.0158 1.27 0.325 9.38E-4 0.09 0.9606 0.7527 2076640 Maybridge3_002974 CCCC(=O)OC1C(Oc2ccccc2C1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H05 compound treatment 0.347 0.0338 2.72 0.329 0.00494 0.45 2.2422 0.8126 2076641 Maybridge3_002975 CCOC(=O)c1cnn2c(=O)c3CCCCc3[nH]c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H06 compound treatment 0.333 0.0198 1.6 0.323 -0.00106 -0.1 1.0599 0.6632 1664247 Maybridge3_002976 CC(=O)Nc1ccc(NC(=O)C2CC2(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H07 compound treatment 0.327 0.0138 1.11 0.333 0.00894 0.81 1.3601 0.988 1879051 Maybridge3_002977 CCOC(=O)c1cnn2c(=O)c3CCCc3[nH]c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H08 compound treatment 0.371 0.0578 4.66 0.319 -0.00506 -0.46 2.967 0.6342 1047844 Maybridge3_002978 OC1(Cc2ccccc2)CCNCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H09 compound treatment 0.325 0.0118 0.95 0.342 0.0179 1.63 1.8239 0.9672 1393091 Maybridge3_002979 O=c1[nH]c-2c(CCc3ccccc32)c(c1C#N)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H10 compound treatment 0.312 -0.00119 -0.1 0.337 0.0129 1.17 0.7628 0.6474 2076642 Maybridge3_002980 OC(=O)CCSc1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H11 compound treatment 0.319 0.00581 0.47 0.348 0.0239 2.17 1.8674 0.8402 2076643 Maybridge3_002981 C1Sc2nnc(c3ccccc3)n2N=C1c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H12 compound treatment 0.326 0.0128 1.03 0.333 0.00894 0.81 1.3032 0.9929 1053054 Maybridge3_002982 O=c1cc(oc2ccccc12)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H13 compound treatment 0.349 0.0358 2.88 0.337 0.0129 1.17 2.8696 0.9216 2076644 Maybridge3_002983 Cc1ccc(cc1)N2CC(=O)Nc3c(sc4nc(C)cc(C)c34)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H14 compound treatment 0.322 0.00881 0.71 0.339 0.0149 1.36 1.4606 0.9544 2076645 Maybridge3_002984 CC(CCC(=O)O)C1CCC2C3C(CC(=O)C12C)C4(C)CCC(=O)CC4CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H15 compound treatment 0.321 0.00781 0.63 0.277 -0.0471 -4.27 -2.5759 -0.5965 2076646 Maybridge3_002985 CC(=O)n1sc2nc(C)cc(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H16 compound treatment 0.316 0.00281 0.23 0.35 0.0259 2.35 1.8249 0.7716 2076647 Maybridge3_002986 CC1(C)C2CCC1(C)C(C2)NS(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H17 compound treatment 0.34 0.0268 2.16 0.349 0.0249 2.26 3.1273 0.9997 2076648 Maybridge3_002987 Nc1c(C#N)sc2nnc(c3ccncc3)n12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H18 compound treatment 0.325 0.0118 0.95 0.333 0.00894 0.81 1.2463 0.9969 2076649 Maybridge3_002988 FC(F)(F)c1ccc(cc1)n2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H19 compound treatment 0.319 0.00581 0.47 0.333 0.00894 0.81 0.9046 0.9658 2076650 Maybridge3_002989 Cc1cc(C)c2c3NC(=O)CN(C(=O)c3oc2n1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H20 compound treatment 0.327 0.0138 1.11 0.344 0.0199 1.81 2.0662 0.9727 1524786 Maybridge3_002990 O=C(Nc1cccc2[nH]ccc12)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H21 compound treatment 0.323 0.00981 0.79 0.335 0.0109 0.99 1.2608 0.9936 2076651 Maybridge3_002991 CCOc1ccc(NC(=O)/C=N/O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H22 compound treatment 0.327 0.0138 1.11 0.33 0.00594 0.54 1.1676 0.9447 1915825 Maybridge3_002992 O=C(Nc1ccc2ccccc2c1)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H23 mock treatment 0.313 -1.88E-4 -0.02 0.325 9.38E-4 0.09 0.0495 0.5727 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 H24 positive control 0.092 -0.221 -17.81 0.093 -0.231 -20.97 -27.4254 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I01 compound treatment 0.331 0.0178 1.43 0.331 0.00694 0.63 1.4595 0.9317 2076652 Maybridge3_002993 Cc1cc(no1)C(=O)Nc2cc(nn2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I02 compound treatment 0.332 0.0188 1.51 0.322 -0.00206 -0.19 0.9388 0.615 2076653 Maybridge3_002994 Cc1c(cnn1c2ccccc2)S(=O)(=O)N3CCCc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I03 compound treatment 0.326 0.0128 1.03 0.328 0.00394 0.36 0.9823 0.8996 2076654 Maybridge3_002995 O=C(OCC1CC(=NO1)c2ccccc2)c3ccc4ccccc4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I04 compound treatment 0.324 0.0108 0.87 0.325 9.38E-4 0.09 0.6758 0.7725 1527073 Maybridge3_002996 O=C(NCC1COc2ccccc2O1)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I05 compound treatment 0.328 0.0148 1.19 0.341 0.0169 1.54 1.9306 0.9921 2076655 Maybridge3_002997 C=CCn1c(Sc2ncnc3n(CC=C)c(=S)sc23)nnc1c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I06 compound treatment 0.331 0.0178 1.43 0.32 -0.00406 -0.37 0.7535 0.5088 2076656 Maybridge3_002998 Cc1ccc(CNS(=O)(=O)c2cccs2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I07 compound treatment 0.326 0.0128 1.03 0.337 0.0129 1.17 1.5599 0.9979 2076657 Maybridge3_002999 O=C1N(CC2CC2)S(=O)(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I08 compound treatment 0.329 0.0158 1.27 0.339 0.0149 1.36 1.8591 0.9995 2076658 Maybridge3_003000 OC(=O)CCCC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I09 compound treatment 0.334 0.0208 1.68 0.35 0.0259 2.35 2.8499 0.9861 2076659 Maybridge3_003001 CCc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I10 compound treatment 0.327 0.0138 1.11 0.345 0.0209 1.9 2.1304 0.9674 2076660 Maybridge3_003002 COc1cccc(Cc2nnc(o2)c3ccc4nsnc4c3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I11 compound treatment 0.329 0.0158 1.27 0.353 0.0289 2.63 2.7577 0.9447 2076661 Maybridge3_003003 Clc1ccc(cc1)C2CCC(CC2)C(=O)NCc3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I12 compound treatment 0.32 0.00681 0.55 0.338 0.0139 1.27 1.2825 0.9301 1085295 Maybridge3_003004 Nc1ncnc2n(CCc3ccccc3)cnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I13 compound treatment 0.33 0.0168 1.35 0.348 0.0239 2.17 2.4937 0.9741 2076662 Maybridge3_003005 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I14 compound treatment 0.331 0.0178 1.43 0.346 0.0219 1.99 2.4223 0.987 2076663 Maybridge3_003006 O=C(Nc1ccc2OCCOc2c1)c3ccc4nsnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I15 compound treatment 0.317 0.00381 0.31 0.371 0.0469 4.26 3.2298 0.7561 1657296 Maybridge3_003007 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I16 compound treatment 0.303 -0.0102 -0.82 0.312 -0.0121 -1.09 -1.3543 -0.9899 2076664 Maybridge3_003008 COC(=O)c1ccc(Oc2ccc(cc2)C3SCCS3)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I17 compound treatment 0.33 0.0168 1.35 0.343 0.0189 1.72 2.1728 0.993 1416967 Maybridge3_003009 O=C(COc1ccccc1)N2c3ccccc3Sc4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I18 compound treatment 0.319 0.00581 0.47 0.341 0.0169 1.54 1.4181 0.8824 2076665 Maybridge3_003010 CC(NCCn1cnc2c(N)ncnc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I19 compound treatment 0.322 0.00881 0.71 0.342 0.0179 1.63 1.6531 0.9307 2076666 Maybridge3_003011 Oc1ccccc1C(=O)NC(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I20 compound treatment 0.331 0.0178 1.43 0.349 0.0249 2.26 2.6149 0.9758 2076667 Maybridge3_003012 FC(F)(F)c1cccc(Nc2cc(nc3ncnn23)c4ccccc4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I21 compound treatment 0.321 0.00781 0.63 0.341 0.0169 1.54 1.532 0.9222 2076668 Maybridge3_003013 Oc1ccccc1c2nc(n[nH]2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I22 compound treatment 0.322 0.00881 0.71 0.343 0.0189 1.72 1.7173 0.9234 2076669 Maybridge3_003014 CCC1C2=C(CC(C)(C)CC2=O)Nc3c1c(C)nn3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I23 mock treatment 0.318 0.00481 0.39 0.334 0.00994 0.9 0.9119 0.9288 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 I24 positive control 0.093 -0.22 -17.73 0.094 -0.23 -20.88 -27.3042 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J01 compound treatment 0.341 0.0278 2.24 0.333 0.00894 0.81 2.1573 0.9057 2076670 Maybridge3_003015 Clc1ccccc1Cn2nnc3c(ncnc23)N4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J02 compound treatment 0.33 0.0168 1.35 0.336 0.0119 1.08 1.7235 0.9939 2076671 Maybridge3_003016 COCOc1ccc(cc1)C(=O)CC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J03 compound treatment 0.322 0.00881 0.71 0.323 -0.00106 -0.1 0.4336 0.6054 2076672 Maybridge3_003017 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NCc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J04 compound treatment 0.325 0.0118 0.95 0.339 0.0149 1.36 1.6314 0.985 2076673 Maybridge3_003018 O=C1/C(=C\c2ccccc2)/Sc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J05 compound treatment 0.321 0.00781 0.63 0.323 -0.00106 -0.1 0.3767 0.5918 1151675 Maybridge3_003019 CCOC(=O)c1cnn2c(=O)cc(C)[nH]c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J06 compound treatment 0.33 0.0168 1.35 0.314 -0.0101 -0.91 0.3115 0.1907 1540118 Maybridge3_003020 O=C(OCC1c2ccccc2-c3ccccc13)ON4C(=O)CCC4=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J07 compound treatment 0.328 0.0148 1.19 0.339 0.0149 1.36 1.8022 0.998 2076674 Maybridge3_003021 CC(=O)Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J08 compound treatment 0.375 0.0618 4.98 0.334 0.00994 0.9 4.1575 0.8219 2076675 Maybridge3_003022 CS/C(=N\N)/NC1(CC2CC3CC(C2)C1)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J09 compound treatment 0.332 0.0188 1.51 0.342 0.0179 1.63 2.2225 0.9994 2076676 Maybridge3_003023 CCn1c(SCC(=O)N2CCCc3ccccc23)nnc1c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J10 compound treatment 0.321 0.00781 0.63 0.332 0.00794 0.72 0.9543 0.9977 1230905 Maybridge3_003024 CNC(=O)c1ccccc1SCCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J11 compound treatment 0.328 0.0148 1.19 0.332 0.00794 0.72 1.3529 0.9709 2076677 Maybridge3_003025 O=C(CSc1nc2ccccc2s1)Nc3c(C#N)cnn3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J12 compound treatment 0.347 0.0338 2.72 0.348 0.0239 2.17 3.4617 0.9937 1704321 Maybridge3_003026 CCOC(=O)COc1ccc2c(=O)cc(oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J13 compound treatment 0.313 -1.88E-4 -0.02 0.335 0.0109 0.99 0.6913 0.6963 2076678 Maybridge3_003027 C1Sc2ccccc2-n3c(nnc13)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J14 compound treatment 0.363 0.0498 4.01 0.333 0.00894 0.81 3.41 0.8332 1007376 Maybridge3_003028 OC(=O)c1ccc(F)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J15 compound treatment 0.326 0.0128 1.03 0.398 0.0739 6.71 5.4752 0.8063 2076679 Maybridge3_003029 COc1cc(/C=C\2/N=C(NC2=O)c3ccccc3)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J16 compound treatment 0.327 0.0138 1.11 0.344 0.0199 1.81 2.0662 0.9727 2076680 Maybridge3_003030 Cc1ccc(cc1)S(=O)(=O)NC2CC3CCC2(C)C3(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J17 compound treatment 0.347 0.0338 2.72 0.338 0.0139 1.27 2.8199 0.9392 2076681 Maybridge3_003031 O=C1CSc2nnc(c3ccncc3)n12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J18 compound treatment 0.33 0.0168 1.35 0.335 0.0109 0.99 1.6593 0.9884 2076682 Maybridge3_003032 CCOC(=O)c1sc(N)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J19 compound treatment 0.321 0.00781 0.63 0.343 0.0189 1.72 1.6604 0.9071 2076683 Maybridge3_003033 O=C(Nc1scc2c1c(=O)oc3ccccc23)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J20 compound treatment 0.318 0.00481 0.39 0.333 0.00894 0.81 0.8477 0.9428 2076684 Maybridge3_003034 FC(F)(F)c1cccc(c1)C(=O)Nc2cccc3[nH]ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J21 compound treatment 0.282 -0.0312 -2.51 0.357 0.0329 2.99 0.3383 0.0866 2076685 Maybridge3_003035 O/C(=C\C(=O)c1ccc(Br)cc1)/C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J22 compound treatment 0.318 0.00481 0.39 0.327 0.00294 0.27 0.4626 0.9833 1198285 Maybridge3_003036 Fc1cccc(c1)C(=O)N(Cc2ccccc2)C(=C)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J23 mock treatment 0.314 8.12E-4 0.07 0.324 -6.25E-5 -0.01 0.0423 0.6434 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 J24 positive control 0.093 -0.22 -17.73 0.093 -0.231 -20.97 -27.3684 -0.9965 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K01 compound treatment 0.332 0.0188 1.51 0.332 0.00794 0.72 1.5807 0.9423 2076686 Maybridge3_003037 CCOC(=O)c1cnn(C(=O)c2ccc(cc2)C(F)(F)F)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K02 compound treatment 0.341 0.0278 2.24 0.323 -0.00106 -0.1 1.5155 0.676 2076687 Maybridge3_003038 O=S(=O)(N1CCCc2ccccc12)c3ccc(cc3)n4cccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K03 compound treatment 0.328 0.0148 1.19 0.325 9.38E-4 0.09 0.9036 0.7556 1306563 Maybridge3_003039 CSc1nnc2NCCCn12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K04 compound treatment 0.327 0.0138 1.11 0.324 -6.25E-5 -0.01 0.7825 0.7035 2076688 Maybridge3_003040 Clc1cc(C(=O)NCC2COc3ccccc3O2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K05 compound treatment 0.324 0.0108 0.87 0.331 0.00694 0.63 1.061 0.9873 1717070 Maybridge3_003041 Cc1nn(c2ccccc2)c3nc(N)c(cc13)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K06 compound treatment 0.344 0.0308 2.48 0.328 0.00394 0.36 2.0072 0.8007 2076689 Maybridge3_003042 Cc1ccc(CNS(=O)(=O)c2ccccc2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K07 compound treatment 0.321 0.00781 0.63 0.321 -0.00306 -0.28 0.2483 0.361 2076690 Maybridge3_003043 O=C1N(Cc2ccc(cc2)c3csnn3)S(=O)(=O)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K08 compound treatment 0.341 0.0278 2.24 0.324 -6.25E-5 -0.01 1.5797 0.7053 2076691 Maybridge3_003044 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K09 compound treatment 0.323 0.00981 0.79 0.355 0.0309 2.81 2.5445 0.8722 1178648 Maybridge3_003045 Cc1ccc(cc1)S(=O)(=O)Nc2cccc3nnc(C)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K10 compound treatment 0.319 0.00581 0.47 0.334 0.00994 0.9 0.9688 0.9533 2076692 Maybridge3_003046 OC(=O)CCC(=O)Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K11 compound treatment 0.321 0.00781 0.63 0.324 -6.25E-5 -0.01 0.4408 0.7007 2076693 Maybridge3_003047 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K12 compound treatment 0.298 -0.0152 -1.22 0.336 0.0119 1.08 -0.0986 -0.0603 2076694 Maybridge3_003048 CCOC(=O)c1cnn(C(=O)Cc2ccsc2)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K13 compound treatment 0.324 0.0108 0.87 0.331 0.00694 0.63 1.061 0.9873 1502073 Maybridge3_003049 O=S(=O)(N1CCCc2ccccc12)c3cccc4nsnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K14 compound treatment 0.321 0.00781 0.63 0.334 0.00994 0.9 1.0827 0.9845 2076695 Maybridge3_003050 Cc1cc(nn1C(C)(C)C)C(=O)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K15 compound treatment 0.32 0.00681 0.55 0.363 0.0389 3.53 2.8871 0.8072 1520276 Maybridge3_003051 N#CCOc1nc(cc(c2ccco2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K16 compound treatment 0.328 0.0148 1.19 0.34 0.0159 1.45 1.8664 0.9954 2076696 Maybridge3_003052 O/N=C\1/CCCCC1Cn2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K17 compound treatment 0.32 0.00681 0.55 0.333 0.00894 0.81 0.9616 0.9818 1141744 Maybridge3_003053 O=C(CSc1nnc[nH]1)N2c3ccccc3Sc4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K18 compound treatment 0.324 0.0108 0.87 0.338 0.0139 1.27 1.5103 0.9834 1026368 Maybridge3_003054 c1ccc2sc(nc2c1)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K19 compound treatment 0.35 0.0368 2.96 0.342 0.0179 1.63 3.2475 0.9602 2076697 Maybridge3_003055 Oc1ccccc1C(=O)NC(=O)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K20 compound treatment 0.319 0.00581 0.47 0.333 0.00894 0.81 0.9046 0.9658 2076698 Maybridge3_003056 Cc1ccc(Nc2cc(nc3ncnn23)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K21 compound treatment 0.328 0.0148 1.19 0.344 0.0199 1.81 2.1231 0.9795 2076699 Maybridge3_003057 COc1ccc(cc1OC)c2nc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K22 compound treatment 0.321 0.00781 0.63 0.332 0.00794 0.72 0.9543 0.9977 2076700 Maybridge3_003058 Cc1cc(C)c2c(n1)sc3c(SCC=C)ncnc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K23 mock treatment 0.313 -1.88E-4 -0.02 0.325 9.38E-4 0.09 0.0495 0.5727 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 K24 positive control 0.095 -0.218 -17.57 0.095 -0.229 -20.79 -27.1262 -0.9965 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L01 compound treatment 0.339 0.0258 2.08 0.338 0.0139 1.27 2.3644 0.9717 2076701 Maybridge3_003059 Clc1ccc(cc1)n2cc(C#N)c(n2)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L02 compound treatment 0.319 0.00581 0.47 0.328 0.00394 0.36 0.5837 0.9911 1467534 Maybridge3_003060 Cc1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L03 compound treatment 0.323 0.00981 0.79 0.326 0.00194 0.18 0.6831 0.8438 2076702 Maybridge3_003061 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NCc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L04 compound treatment 0.334 0.0208 1.68 0.324 -6.25E-5 -0.01 1.1811 0.7047 2076703 Maybridge3_003062 Cc1ccccc1/C=C\2/Sc3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L05 compound treatment 0.331 0.0178 1.43 0.335 0.0109 0.99 1.7163 0.9839 2076704 Maybridge3_003063 CCOC(=O)c1cnn2c(=O)cc([nH]c12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L06 compound treatment 0.332 0.0188 1.51 0.338 0.0139 1.27 1.9658 0.996 1723317 Maybridge3_003064 COC(=O)C(Cc1ccccc1)NC(=O)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L07 compound treatment 0.326 0.0128 1.03 0.342 0.0179 1.63 1.8809 0.9758 2076705 Maybridge3_003065 Clc1ccc(Oc2ncnc3n(Cc4ccccc4)nnc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L08 compound treatment 0.333 0.0198 1.6 0.34 0.0159 1.45 2.1511 0.9988 2076706 Maybridge3_003066 Clc1ccc(cc1)C(=O)/C=C/2\SCC(=O)N2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L09 compound treatment 0.328 0.0148 1.19 0.342 0.0179 1.63 1.9948 0.9883 2076707 Maybridge3_003067 Nc1nc(SCc2ccc(Cl)cc2)ncc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L10 compound treatment 0.34 0.0268 2.16 0.344 0.0199 1.81 2.8064 0.9961 1128028 Maybridge3_003068 OC(=O)CCSc1cccc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L11 compound treatment 0.321 0.00781 0.63 0.332 0.00794 0.72 0.9543 0.9977 2076708 Maybridge3_003069 Clc1ccccc1CSc2nnc3NCCCn23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L12 compound treatment 0.344 0.0308 2.48 0.34 0.0159 1.45 2.7774 0.967 1041430 Maybridge3_003070 CC(=O)Nc1c(oc2ccccc2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L13 compound treatment 0.319 0.00581 0.47 0.346 0.0219 1.99 1.739 0.8501 2076709 Maybridge3_003071 Cc1nc2sc(cc2c(=O)o1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L14 compound treatment 0.325 0.0118 0.95 0.339 0.0149 1.36 1.6314 0.985 2076710 Maybridge3_003072 OC(=O)CCCCc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L15 compound treatment 0.327 0.0138 1.11 0.336 0.0119 1.08 1.5527 0.9999 2076711 Maybridge3_003073 O=c1[nH]cnc2sc(cc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L16 compound treatment 0.324 0.0108 0.87 0.339 0.0149 1.36 1.5744 0.9771 1524655 Maybridge3_003074 CC(C)C1CCC(C)CC1NC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L17 compound treatment 0.329 0.0158 1.27 0.34 0.0159 1.45 1.9233 0.998 2076712 Maybridge3_003075 Nc1ncnc2nc(ncc12)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L18 compound treatment 0.357 0.0438 3.53 0.356 0.0319 2.9 4.5446 0.9952 1233522 Maybridge3_003076 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2C(C)(C)C3CCC2(C)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L19 compound treatment 0.328 0.0148 1.19 0.346 0.0219 1.99 2.2515 0.97 2076713 Maybridge3_003077 NS(=O)(=O)c1ccc(NC(=O)CN2CCCc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L20 compound treatment 0.327 0.0138 1.11 0.357 0.0329 2.99 2.9006 0.9093 1696824 Maybridge3_003078 COc1ccccc1N2CCN(CC2)C(=O)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L21 compound treatment 0.321 0.00781 0.63 0.334 0.00994 0.9 1.0827 0.9845 1733585 Maybridge3_003079 COc1ccc(cc1OC)C(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L22 compound treatment 0.324 0.0108 0.87 0.336 0.0119 1.08 1.3819 0.9941 2076714 Maybridge3_003080 CCOC(=O)CSc1nnnn1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L23 mock treatment 0.316 0.00281 0.23 0.331 0.00694 0.63 0.6054 0.9047 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 L24 positive control 0.094 -0.219 -17.65 0.095 -0.229 -20.79 -27.1831 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M01 compound treatment 0.323 0.00981 0.79 0.337 0.0129 1.17 1.3891 0.9814 2076715 Maybridge3_003081 OC(=O)COCC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M02 compound treatment 0.33 0.0168 1.35 0.326 0.00194 0.18 1.0817 0.7923 1671891 Maybridge3_003082 OC(=O)c1ccccc1C(=O)N2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M03 compound treatment 0.338 0.0248 2.0 0.333 0.00894 0.81 1.9865 0.9212 2076716 Maybridge3_003083 CCOc1ncnc2sc3CCCCc3c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M04 compound treatment 0.327 0.0138 1.11 0.325 9.38E-4 0.09 0.8467 0.759 2076717 Maybridge3_003084 Cc1nnsc1C(=O)NCC2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M05 compound treatment 0.351 0.0378 3.04 0.327 0.00294 0.27 2.3416 0.7661 1603526 Maybridge3_003085 Cn1ccnc1SCC(=O)N2c3ccccc3Sc4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M06 compound treatment 0.332 0.0188 1.51 0.333 0.00894 0.81 1.6449 0.9572 2076718 Maybridge3_003086 Fc1ccc(CN2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M07 compound treatment 0.32 0.00681 0.55 0.33 0.00594 0.54 0.769 1.0 2076719 Maybridge3_003087 Oc1ccccc1C(=O)NC(=O)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M08 compound treatment 0.322 0.00881 0.71 0.331 0.00694 0.63 0.9471 0.9982 2076720 Maybridge3_003088 CC(C)S(=O)(=O)c1csc(C(=O)Nc2ccc(F)cc2)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M09 compound treatment 0.323 0.00981 0.79 0.329 0.00494 0.45 0.8756 0.9639 2076721 Maybridge3_003089 Fc1ccc(cc1)C(=O)CN2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M10 compound treatment 0.328 0.0148 1.19 0.331 0.00694 0.63 1.2887 0.9554 2076722 Maybridge3_003090 OC(=O)CSCC(=O)Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M11 compound treatment 0.337 0.0238 1.92 0.321 -0.00306 -0.28 1.1593 0.5983 1444526 Maybridge3_003091 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(O)c(O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M12 compound treatment 0.338 0.0248 2.0 0.333 0.00894 0.81 1.9865 0.9212 2076723 Maybridge3_003092 Cc1nc(n[nH]1)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M13 compound treatment 0.319 0.00581 0.47 0.342 0.0179 1.63 1.4823 0.8749 2076724 Maybridge3_003093 Cc1onc(c1C(=O)NC(CN2CCOCC2)c3ccccc3)c4c(F)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M14 compound treatment 0.318 0.00481 0.39 0.321 -0.00306 -0.28 0.0775 0.1624 2076725 Maybridge3_003094 O=C(Nc1ccc2OCCOc2c1)c3ncoc3c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M15 compound treatment 0.32 0.00681 0.55 0.329 0.00494 0.45 0.7048 0.995 1385209 Maybridge3_003095 CCOC(=O)COc1nc(cc(c2ccco2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M16 compound treatment 0.361 0.0478 3.85 0.33 0.00594 0.54 3.1036 0.7983 1628910 Maybridge3_003096 OC(=O)Cn1c2ccccc2c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M17 compound treatment 0.311 -0.00219 -0.18 0.346 0.0219 1.99 1.2835 0.642 2076726 Maybridge3_003097 Brc1ccc(cc1)C(=O)CSc2nnc(o2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M18 compound treatment 0.323 0.00981 0.79 0.327 0.00294 0.27 0.7473 0.8961 2076727 Maybridge3_003098 Nc1cc(Cl)ccc1Nc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M19 compound treatment 0.325 0.0118 0.95 0.352 0.0279 2.54 2.4658 0.9104 2076728 Maybridge3_003099 Cc1nnsc1C(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M20 compound treatment 0.352 0.0388 3.13 0.335 0.0109 0.99 2.912 0.888 2076729 Maybridge3_003100 Clc1ccc(Nc2cc(nc3ncnn23)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M21 compound treatment 0.341 0.0278 2.24 0.33 0.00594 0.54 1.9648 0.8529 2076730 Maybridge3_003101 FC(F)(F)c1ccccc1NS(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M22 compound treatment 0.34 0.0268 2.16 0.331 0.00694 0.63 1.972 0.8768 2076731 Maybridge3_003102 Cc1cc(C)c2c(n1)sc3c(Sc4nccn4C)ncnc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M23 mock treatment 0.311 -0.00219 -0.18 0.32 -0.00406 -0.37 -0.3853 -0.9428 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 M24 positive control 0.096 -0.217 -17.49 0.096 -0.228 -20.7 -27.005 -0.9965 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N01 compound treatment 0.331 0.0178 1.43 0.364 0.0399 3.63 3.5777 0.9177 2076732 Maybridge3_003103 Cc1ccc(cc1)n2cc(C#N)c(n2)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N02 compound treatment 0.334 0.0208 1.68 0.335 0.0109 0.99 1.8871 0.9688 1329051 Maybridge3_003104 COc1ccc(cc1)c2cc(=O)c3cc(F)ccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N03 compound treatment 0.318 0.00481 0.39 0.337 0.0129 1.17 1.1044 0.8931 2076733 Maybridge3_003105 CC(=O)Nc1c(sc2nc(C)cc(C)c12)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N04 compound treatment 0.321 0.00781 0.63 0.325 9.38E-4 0.09 0.505 0.7955 2076734 Maybridge3_003106 Cc1cccc(/C=C\2/Sc3ccccc3C2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N05 compound treatment 0.327 0.0138 1.11 0.332 0.00794 0.72 1.296 0.9779 1820764 Maybridge3_003107 O=C(CSc1ccccc1)N2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N06 compound treatment 0.335 0.0218 1.76 0.333 0.00894 0.81 1.8157 0.9384 2076735 Maybridge3_003108 CCOC(=O)c1c(NC(=O)C(F)(F)F)sc2CCCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N07 compound treatment 0.323 0.00981 0.79 0.323 -0.00106 -0.1 0.4905 0.6162 2076736 Maybridge3_003109 Nc1nc(Nc2cccc(c2)C(F)(F)F)ncc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N08 compound treatment 0.327 0.0138 1.11 0.333 0.00894 0.81 1.3601 0.988 1424787 Maybridge3_003110 CCOC(=O)CN1C(=O)C2(OCCO2)c3cc(Br)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N09 compound treatment 0.318 0.00481 0.39 0.341 0.0169 1.54 1.3612 0.8585 2076737 Maybridge3_003111 Nc1nc(Sc2nc3ccccc3s2)ncc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N10 compound treatment 0.348 0.0348 2.8 0.337 0.0129 1.17 2.8126 0.9254 1560631 Maybridge3_003112 CNS(=O)(=O)c1ccccc1Sc2cccc3cccc(C(=O)O)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N11 compound treatment 0.324 0.0108 0.87 0.332 0.00794 0.72 1.1251 0.9956 2076738 Maybridge3_003113 O=C(N1CCCn2c(SCc3ccccc3)nnc12)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N12 compound treatment 0.331 0.0178 1.43 0.348 0.0239 2.17 2.5507 0.9797 1377352 Maybridge3_003114 Nc1c(oc2ccccc2c1=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N13 compound treatment 0.34 0.0268 2.16 0.34 0.0159 1.45 2.5497 0.981 2076739 Maybridge3_003115 Nc1c(C#N)cnn1c2ncnc3sc4CCCCc4c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N14 compound treatment 0.331 0.0178 1.43 0.338 0.0139 1.27 1.9088 0.998 1523192 Maybridge3_003116 CN(C)c1ccc(cc1)C2Nc3[nH]nc(C)c3C4=C2C(=O)CC(C)(C)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N15 compound treatment 0.323 0.00981 0.79 0.355 0.0309 2.81 2.5445 0.8722 2076740 Maybridge3_003117 CCOC(=O)c1cc(sc1NC(=O)CSc2nccn2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N16 compound treatment 0.33 0.0168 1.35 0.335 0.0109 0.99 1.6593 0.9884 2076741 Maybridge3_003118 CCOC(NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N17 compound treatment 0.325 0.0118 0.95 0.339 0.0149 1.36 1.6314 0.985 1411244 Maybridge3_003119 C1CCN(C1)c2ncnc3n(ncc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N18 compound treatment 0.334 0.0208 1.68 0.328 0.00394 0.36 1.4378 0.839 1382805 Maybridge3_003120 CC1(C)C(NS(=O)(=O)c2ccc(F)cc2)C3(C)CCC1C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N19 compound treatment 0.324 0.0108 0.87 0.338 0.0139 1.27 1.5103 0.9834 2076742 Maybridge3_003121 NS(=O)(=O)c1ccc(NC(=O)CN2CCc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N20 compound treatment 0.319 0.00581 0.47 0.356 0.0319 2.9 2.3809 0.8108 1501899 Maybridge3_003122 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N21 compound treatment 0.318 0.00481 0.39 0.326 0.00194 0.18 0.3984 0.9361 1170387 Maybridge3_003123 CCOC(=O)C1=C(C)NCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N22 compound treatment 0.319 0.00581 0.47 0.326 0.00194 0.18 0.4553 0.9106 1551452 Maybridge3_003124 OC(C1CCCN1)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N23 mock treatment 0.316 0.00281 0.23 0.327 0.00294 0.27 0.3487 0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 N24 positive control 0.094 -0.219 -17.65 0.096 -0.228 -20.7 -27.1189 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O01 compound treatment 0.339 0.0258 2.08 0.339 0.0149 1.36 2.4285 0.9786 2076743 Maybridge3_003125 FC(F)(F)c1ccc(cc1)c2nnc(o2)c3ccc4nsnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O02 compound treatment 0.4 0.0868 6.99 0.338 0.0139 1.27 5.8378 0.8217 2076744 Maybridge3_003126 FC(F)(F)c1ccccc1NC(=O)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O03 compound treatment 0.329 0.0158 1.27 0.344 0.0199 1.81 2.1801 0.9852 1273536 Maybridge3_003127 COc1cccc(c1)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O04 compound treatment 0.342 0.0288 2.32 0.332 0.00794 0.72 2.1501 0.885 1467853 Maybridge3_003128 O=S(=O)(NCC1COc2ccccc2O1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O05 compound treatment 0.332 0.0188 1.51 0.331 0.00694 0.63 1.5165 0.9244 2076745 Maybridge3_003129 Cc1nc(Sc2nnc[nH]2)c3sc(=S)n(c4ccccc4)c3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O06 compound treatment 0.344 0.0308 2.48 0.352 0.0279 2.54 3.5477 0.9999 2076746 Maybridge3_003130 Clc1ccc(CCN2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O07 compound treatment 0.327 0.0138 1.11 0.34 0.0159 1.45 1.8094 0.9916 2076747 Maybridge3_003131 Cc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O08 compound treatment 0.34 0.0268 2.16 0.338 0.0139 1.27 2.4213 0.9676 2076748 Maybridge3_003132 O=S(=O)(N1CCOCC1)c2ccc(CN3CCOCC3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O09 compound treatment 0.328 0.0148 1.19 0.337 0.0129 1.17 1.6738 1.0 1236448 Maybridge3_003133 N#Cc1ccc(cc1)c2cn3CCSc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O10 compound treatment 0.328 0.0148 1.19 0.334 0.00994 0.9 1.4813 0.9905 2076749 Maybridge3_003134 CCCSc1ncccc1C(=O)Nc2c(C)noc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O11 compound treatment 0.329 0.0158 1.27 0.361 0.0369 3.35 3.2712 0.9121 2076750 Maybridge3_003135 Clc1ccc(CSc2nc(NC(=O)c3cccs3)n[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O12 compound treatment 0.327 0.0138 1.11 0.37 0.0459 4.17 3.735 0.8655 2076751 Maybridge3_003136 Clc1cccc(c1)c2n[nH]c(n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O13 compound treatment 0.325 0.0118 0.95 0.349 0.0249 2.26 2.2732 0.9258 2076752 Maybridge3_003137 Cn1nc(cc1NC(=O)c2cc(Cl)sc2Cl)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O14 compound treatment 0.324 0.0108 0.87 0.335 0.0109 0.99 1.3177 0.9979 2076753 Maybridge3_003138 Cc1cc(no1)C(=O)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O15 compound treatment 0.329 0.0158 1.27 0.356 0.0319 2.9 2.9503 0.9318 1148356 Maybridge3_003139 O=c1[nH]c(cc(c2cccs2)c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O16 compound treatment 0.353 0.0398 3.21 0.337 0.0129 1.17 3.0974 0.9072 2076754 Maybridge3_003140 CC(C)CNC(=O)C1CC(=NO1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O17 compound treatment 0.326 0.0128 1.03 0.335 0.0109 0.99 1.4316 0.9998 2076755 Maybridge3_003141 Clc1ccccc1CSc2nnc(o2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O18 compound treatment 0.33 0.0168 1.35 0.342 0.0179 1.63 2.1086 0.9958 2076756 Maybridge3_003142 Cc1cc(nc2oc3c(=O)[nH]cnc3c12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O19 compound treatment 0.328 0.0148 1.19 0.338 0.0139 1.27 1.738 0.9996 2076757 Maybridge3_003143 Oc1ccccc1C(=O)NC(=O)c2cc(oc2C(F)(F)F)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O20 compound treatment 0.33 0.0168 1.35 0.347 0.0229 2.08 2.4296 0.9783 2076758 Maybridge3_003144 C/C(=C\1/CCOC1=O)/Nc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O21 compound treatment 0.346 0.0328 2.64 0.354 0.0299 2.72 3.7899 0.9999 2076759 Maybridge3_003145 CS(=O)(=O)N(Cc1ccccc1)Cc2ccccc2N3CCC(CC3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O22 compound treatment 0.331 0.0178 1.43 0.342 0.0179 1.63 2.1656 0.998 2076760 Maybridge3_003146 CCOc1ncnc2c1sc3nc(C)cc(C)c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O23 mock treatment 0.322 0.00881 0.71 0.334 0.00994 0.9 1.1396 0.9929 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 O24 positive control 0.095 -0.218 -17.57 0.096 -0.228 -20.7 -27.062 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P01 compound treatment 0.327 0.0138 1.11 0.33 0.00594 0.54 1.1676 0.9447 2076761 Maybridge3_003147 CCOC(=O)c1nn(cc1C#N)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P02 compound treatment 0.326 0.0128 1.03 0.324 -6.25E-5 -0.01 0.7255 0.7032 1672168 Maybridge3_003148 Cc1c(oc2ccccc2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P03 compound treatment 0.316 0.00281 0.23 0.325 9.38E-4 0.09 0.2203 0.9106 2076762 Maybridge3_003149 CCOc1ncnc2n(Cc3ccccc3Cl)nnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P04 compound treatment 0.321 0.00781 0.63 0.325 9.38E-4 0.09 0.505 0.7955 2076763 Maybridge3_003150 O=C(c1ccccc1)C2(CC2c3ccccc3)C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P05 compound treatment 0.327 0.0138 1.11 0.33 0.00594 0.54 1.1676 0.9447 2076764 Maybridge3_003151 CN1CCN(CC1)c2ncc(C#N)c(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P06 compound treatment 0.328 0.0148 1.19 0.334 0.00994 0.9 1.4813 0.9905 2076765 Maybridge3_003152 O=C1CCC2=C(CCCC2)N1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P07 compound treatment 0.321 0.00781 0.63 0.323 -0.00106 -0.1 0.3767 0.5918 2076766 Maybridge3_003153 Clc1ccc(cc1)c2nnc(Sc3ncnc4n(CC=C)c(=S)sc34)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P08 compound treatment 0.327 0.0138 1.11 0.329 0.00494 0.45 1.1034 0.9201 1458196 Maybridge3_003154 OC(c1c[nH]c2ccccc12)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P09 compound treatment 0.321 0.00781 0.63 0.343 0.0189 1.72 1.6604 0.9071 2076767 Maybridge3_003155 Nc1nc(Nc2ccc(F)cc2)ncc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P10 compound treatment 0.36 0.0468 3.77 0.474 0.15 13.61 12.2893 0.8702 2076768 Maybridge3_003156 OCC(O)C(O)C(O)C1Nc2ccccc2S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P11 compound treatment 0.322 0.00881 0.71 0.329 0.00494 0.45 0.8187 0.9754 2076769 Maybridge3_003157 CCOC(=O)CSc1nnc2sc3ccccc3n12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P12 compound treatment 0.331 0.0178 1.43 0.328 0.00394 0.36 1.267 0.8571 1022251 Maybridge3_003158 COC(=O)NCc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P13 compound treatment 0.343 0.0298 2.4 0.332 0.00794 0.72 2.207 0.8805 1061573 Maybridge3_003159 Cc1nc2n(ncc2c(=O)o1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P14 compound treatment 0.329 0.0158 1.27 0.334 0.00994 0.9 1.5382 0.9857 1162219 Maybridge3_003160 O=S1(=O)CC(CS(=O)(=O)C1CCN2CCOCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P15 compound treatment 0.323 0.00981 0.79 0.326 0.00194 0.18 0.6831 0.8438 2076770 Maybridge3_003161 CCOC(=O)CSc1nc(cn1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P16 compound treatment 0.316 0.00281 0.23 0.309 -0.0151 -1.37 -0.8066 -0.582 2076771 Maybridge3_003162 COc1cccc(c1)I(OC(=O)C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P17 compound treatment 0.327 0.0138 1.11 0.333 0.00894 0.81 1.3601 0.988 2076772 Maybridge3_003163 Clc1ccc(cc1)c2nnc3sc(=Cc4cccs4)c(=O)n23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P18 compound treatment 0.316 0.00281 0.23 0.326 0.00194 0.18 0.2845 0.9922 2076773 Maybridge3_003164 CC1(C)C(NC(=O)c2ccco2)C3(C)CCC1C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P19 compound treatment 0.32 0.00681 0.55 0.396 0.0719 6.53 5.0052 0.7638 2076774 Maybridge3_003165 Nc1nc(cc(c2ccco2)c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P20 compound treatment 0.322 0.00881 0.71 0.333 0.00894 0.81 1.0754 0.9978 2076775 Maybridge3_003166 C(=C/c1ccccc1)\C=N\c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P21 compound treatment 0.324 0.0108 0.87 0.357 0.0329 2.99 2.7298 0.8766 2076776 Maybridge3_003167 N#CCc1c2ccccc2c(CC#N)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P22 compound treatment 0.323 0.00981 0.79 0.334 0.00994 0.9 1.1966 0.9978 2076777 Maybridge3_003168 CS(=O)(=O)c1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P23 mock treatment 0.314 8.12E-4 0.07 0.326 0.00194 0.18 0.1706 0.9093 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1439 P24 positive control 0.1 -0.213 -17.17 0.098 -0.226 -20.52 -26.6489 -0.9961 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A01 compound treatment 0.309 -0.00244 -0.2 0.309 0.00375 0.34 0.1019 0.2593 1068648 Maybridge3_003169 CS(=O)(=O)c1ccccc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A02 compound treatment 0.31 -0.00144 -0.12 0.32 0.0147 1.34 0.8649 0.6436 1446178 Maybridge3_003170 CC(Nc1ccccc1)(C#N)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A03 compound treatment 0.31 -0.00144 -0.12 0.305 -2.5E-4 -0.02 -0.0979 -0.8299 2076778 Maybridge3_003171 N#Cc1cc(Sc2ccccn2)c(Sc3ccccn3)cc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A04 compound treatment 0.313 0.00156 0.13 0.305 -2.5E-4 -0.02 0.0729 0.5704 1939240 Maybridge3_003172 Cc1ccc(o1)c2ccccc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A05 compound treatment 0.313 0.00156 0.13 0.304 -0.00125 -0.11 0.0087 0.0516 1064867 Maybridge3_003173 CC(O)(C(=O)O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A06 compound treatment 0.307 -0.00444 -0.36 0.302 -0.00325 -0.3 -0.4613 -0.9955 2076779 Maybridge3_003174 COC(=O)CC1CS(=O)(=O)C=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A07 compound treatment 0.264 -0.0474 -3.82 0.264 -0.0413 -3.74 -5.3488 -0.9999 2076780 Maybridge3_003175 Cc1ccc(cc1)C(=O)C#Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A08 compound treatment 0.302 -0.00944 -0.76 0.295 -0.0103 -0.93 -1.1953 -0.995 1172461 Maybridge3_003176 Nc1[nH]nc(c1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A09 compound treatment 0.304 -0.00744 -0.6 0.297 -0.00825 -0.75 -0.953 -0.9939 2076781 Maybridge3_003177 Cc1cc(C)c(CO)cc1CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A10 compound treatment 0.219 -0.0924 -7.44 0.209 -0.0963 -8.74 -11.4413 -0.9968 1043206 Maybridge3_003178 NC(=O)C1=C(CCCC1)N=C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A11 compound treatment 0.311 -4.37E-4 -0.04 0.304 -0.00125 -0.11 -0.1051 -0.885 1661951 Maybridge3_003179 O=C(Cc1ccccc1)N2CCC(CC2)NC(=O)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A12 compound treatment 0.303 -0.00844 -0.68 0.303 -0.00225 -0.2 -0.6249 -0.8807 1253602 Maybridge3_003180 O=C(Oc1cc(=O)n(c2ccccc2)c3ccccc13)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A13 compound treatment 0.314 0.00256 0.21 0.312 0.00675 0.61 0.5792 0.8958 1193425 Maybridge3_003181 O=c1cc(oc2ccccc12)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A14 compound treatment 0.298 -0.0134 -1.08 0.294 -0.0113 -1.02 -1.4872 -0.9996 2076782 Maybridge3_003182 CCSc1nc(O)nc(n1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A15 compound treatment 0.217 -0.0944 -7.6 0.21 -0.0953 -8.65 -11.491 -0.998 2076783 Maybridge3_003183 CCC1=CC(=O)C=C(CC)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A16 compound treatment 0.305 -0.00644 -0.52 0.301 -0.00425 -0.39 -0.6393 -0.9894 2076784 Maybridge3_003184 Brc1ccc(NC(=O)/C=C/c2ccc3OCOc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A17 compound treatment 0.304 -0.00744 -0.6 0.299 -0.00625 -0.57 -0.8247 -0.9996 2076785 Maybridge3_003185 CC(C)(C)C(CO)/N=C/c1cccc(\C=N\C(CO)C(C)(C)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A18 compound treatment 0.312 5.63E-4 0.05 0.305 -2.5E-4 -0.02 0.016 0.3155 2076786 Maybridge3_003186 CC(=O)Nc1ccc(OC(=O)c2cccc(Cl)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A19 compound treatment 0.31 -0.00144 -0.12 0.307 0.00175 0.16 0.0305 0.155 1418073 Maybridge3_003187 Cc1cc(C)c2c(N)c(sc2n1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A20 compound treatment 0.318 0.00656 0.53 0.313 0.00775 0.7 0.8711 0.9901 2076787 Maybridge3_003188 COc1cc2CCN/C(=C/C#N)/c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A21 compound treatment 0.306 -0.00544 -0.44 0.301 -0.00425 -0.39 -0.5824 -0.998 2076788 Maybridge3_003189 CCOC(=O)c1ccc(cc1)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A22 compound treatment 0.499 0.188 15.1 0.48 0.175 15.86 21.8963 0.9997 2076789 Maybridge3_003190 N/C(=C(/N=C/c1cccs1)\C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A23 mock treatment 0.301 -0.0104 -0.84 0.293 -0.0123 -1.11 -1.3806 -0.9905 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 A24 positive control 0.082 -0.229 -18.48 0.079 -0.226 -20.54 -27.5862 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B01 compound treatment 0.33 0.0186 1.49 0.328 0.0227 2.07 2.5172 0.9874 1669047 Maybridge3_003191 CC(C)(C)c1cc2[nH]c(cc(=O)n2n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B02 compound treatment 0.334 0.0226 1.82 0.332 0.0267 2.43 3.0017 0.9898 2076790 Maybridge3_003192 Clc1ccc(CS(=O)(=O)/C(=C/NCc2cccnc2)/C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B03 compound treatment 0.329 0.0176 1.41 0.329 0.0238 2.16 2.5244 0.9791 2076791 Maybridge3_003193 COc1cccc(c1)C(=O)/C=C/2\NC(=O)CS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B04 compound treatment 0.344 0.0326 2.62 0.34 0.0348 3.15 4.0846 0.9958 2076792 Maybridge3_003194 O=S(=O)(/C(=C/c1ccc(C#N)cc1)/C#N)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B05 compound treatment 0.313 0.00156 0.13 0.307 0.00175 0.16 0.2013 0.9933 2076793 Maybridge3_003195 Fc1cccc(Cl)c1CN/C(=C(\NCc2ccccc2)/C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B06 compound treatment 0.337 0.0256 2.06 0.331 0.0257 2.34 3.1083 0.998 2076794 Maybridge3_003196 Fc1ccc(N/C=C(\C#N)/S(=O)(=O)c2nc3ccccc3s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B07 compound treatment 0.327 0.0156 1.25 0.324 0.0187 1.7 2.0896 0.9887 1205401 Maybridge3_003197 O=c1c2CSCc2[nH]c3cc(nn13)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B08 compound treatment 0.34 0.0286 2.3 0.334 0.0288 2.61 3.4717 0.998 2076795 Maybridge3_003198 CN1c2ccccc2C(=O)/C(=C\Nc3cccnc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B09 compound treatment 0.328 0.0166 1.33 0.326 0.0208 1.88 2.2749 0.9857 1669057 Maybridge3_003199 Nc1c(C#N)cnc2cc(nn12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B10 compound treatment 0.312 5.63E-4 0.05 0.309 0.00375 0.34 0.2727 0.7942 2076796 Maybridge3_003200 Cc1c(csc1C(=O)NCc2ccco2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B11 compound treatment 0.324 0.0126 1.01 0.323 0.0177 1.61 1.8546 0.9749 1593149 Maybridge3_003201 Nc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B12 compound treatment 0.318 0.00656 0.53 0.314 0.00875 0.79 0.9353 0.9804 2076797 Maybridge3_003202 CCCSc1sc(C(=O)OC)c(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B13 compound treatment 0.322 0.0106 0.85 0.316 0.0107 0.98 1.2914 0.9977 2076798 Maybridge3_003203 Clc1ccc(cc1)S(=O)(=O)/C(=C/NC2CCCCC2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B14 compound treatment 0.317 0.00556 0.45 0.31 0.00475 0.43 0.6216 0.9998 2076799 Maybridge3_003204 CSc1nc(nc(C2CC2)c1C#N)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B15 compound treatment 0.316 0.00456 0.37 0.309 0.00375 0.34 0.5005 0.9993 2076800 Maybridge3_003205 CSc1nc2cc(C)nn2c(c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B16 compound treatment 0.319 0.00756 0.61 0.312 0.00675 0.61 0.8639 1.0 2076801 Maybridge3_003206 CCCS(=O)(=O)c1csc(C(=O)OC)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B17 compound treatment 0.32 0.00856 0.69 0.315 0.00975 0.89 1.1134 0.9924 2076802 Maybridge3_003207 CSC(=C(C#N)S(=O)(=O)c1ccc(Cl)cc1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B18 compound treatment 0.326 0.0146 1.17 0.321 0.0158 1.43 1.8401 0.9952 1656251 Maybridge3_003208 Cc1c(cnc2cc(nn12)C3CC3)S(=O)(=O)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B19 compound treatment 0.32 0.00856 0.69 0.314 0.00875 0.79 1.0492 0.9975 2076803 Maybridge3_003209 Cc1ccc(cc1)S(=O)(=O)C(=C2SCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B20 compound treatment 0.33 0.0186 1.49 0.328 0.0227 2.07 2.5172 0.9874 2076804 Maybridge3_003210 CSc1nc2cc(C)nn2c(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B21 compound treatment 0.318 0.00656 0.53 0.315 0.00975 0.89 0.9995 0.9696 2076805 Maybridge3_003211 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(Cl)cc1)/NCc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B22 compound treatment 0.316 0.00456 0.37 0.312 0.00675 0.61 0.693 0.9701 2076806 Maybridge3_003212 CC(C)S(=O)(=O)c1csc(C(=O)OCC(=O)c2ccccc2)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B23 mock treatment 0.313 0.00156 0.13 0.308 0.00275 0.25 0.2655 0.9497 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 B24 positive control 0.082 -0.229 -18.48 0.079 -0.226 -20.54 -27.5862 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C01 compound treatment 0.325 0.0136 1.09 0.32 0.0147 1.34 1.719 0.9949 1104734 Maybridge3_003213 CCOc1nc2ccccc2nc1OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C02 compound treatment 0.32 0.00856 0.69 0.319 0.0138 1.25 1.3701 0.9609 1311281 Maybridge3_003214 OC(c1ccccc1)c2ccc3ccccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C03 compound treatment 0.315 0.00356 0.29 0.31 0.00475 0.43 0.5077 0.9804 1510028 Maybridge3_003215 CC(=O)NC1(CC2CC3C1)CC(C2)(C3)NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C04 compound treatment 0.321 0.00956 0.77 0.322 0.0168 1.52 1.6196 0.9503 1447901 Maybridge3_003216 CCc1cc(C(=O)OC)c(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C05 compound treatment 0.325 0.0136 1.09 0.317 0.0118 1.07 1.5264 0.9999 1081649 Maybridge3_003217 C1CSC(SC1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C06 compound treatment 0.311 -4.37E-4 -0.04 0.309 0.00375 0.34 0.2158 0.6306 1273375 Maybridge3_003218 Nc1nc(N)c(Cc2ccccc2)cc1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C07 compound treatment 0.323 0.0116 0.93 0.319 0.0138 1.25 1.5409 0.9896 1046863 Maybridge3_003219 COc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C08 compound treatment 0.381 0.0696 5.6 0.387 0.0818 7.42 9.2081 0.9904 2076807 Maybridge3_003220 Oc1nc2ccccc2nc1c3c[nH]c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C09 compound treatment 0.316 0.00456 0.37 0.315 0.00975 0.89 0.8856 0.9242 1390805 Maybridge3_003221 COC(=O)C1=C(O)c2cccc3CCCN(C1)c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C10 compound treatment 0.317 0.00556 0.45 0.321 0.0158 1.43 1.3276 0.8862 1535739 Maybridge3_003222 OC(C(O)C(=O)Nc1ccc(Cl)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C11 compound treatment 0.319 0.00756 0.61 0.315 0.00975 0.89 1.0564 0.9834 1741837 Maybridge3_003223 O=C(NC1CCN(CC1)C(=O)C2CCCCC2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C12 compound treatment 0.326 0.0146 1.17 0.314 0.00875 0.79 1.3908 0.982 1076384 Maybridge3_003224 CCOC(=O)c1cncc(c1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C13 compound treatment 0.314 0.00256 0.21 0.319 0.0138 1.25 1.0285 0.813 2076808 Maybridge3_003225 COc1cccc(c1)c2coc3cc(O)ccc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C14 compound treatment 0.326 0.0146 1.17 0.314 0.00875 0.79 1.3908 0.982 2076809 Maybridge3_003226 Oc1cc(Nc2cccc(c2)C(F)(F)F)ncn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C15 compound treatment 0.318 0.00656 0.53 0.31 0.00475 0.43 0.6786 0.9949 1031533 Maybridge3_003227 O=S(=O)(CS(=O)(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C16 compound treatment 0.327 0.0156 1.25 0.316 0.0107 0.98 1.5761 0.9923 2076810 Maybridge3_003228 O=C(/C=C/c1cccc2ccccc12)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C17 compound treatment 0.318 0.00656 0.53 0.318 0.0127 1.16 1.192 0.9369 1618528 Maybridge3_003229 CC(=O)Oc1ccc(CC2SC(=O)NC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C18 compound treatment 0.316 0.00456 0.37 0.308 0.00275 0.25 0.4363 0.9823 2076811 Maybridge3_003230 Nc1ccc(Cl)cc1c2ncon2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C19 compound treatment 0.318 0.00656 0.53 0.312 0.00675 0.61 0.8069 0.9973 2076812 Maybridge3_003231 CC(C)(C)C1=CC(O)(C=C(C1=O)C(C)(C)C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C20 compound treatment 0.318 0.00656 0.53 0.311 0.00575 0.52 0.7427 1.0 1396441 Maybridge3_003232 COc1ccccc1c2cc3nc(C)cc(C)n3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C21 compound treatment 0.32 0.00856 0.69 0.33 0.0248 2.25 2.0761 0.8835 2076813 Maybridge3_003233 CS/C(=N/c1ccc(Cl)cc1)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C22 compound treatment 0.313 0.00156 0.13 0.309 0.00375 0.34 0.3297 0.9084 1191386 Maybridge3_003234 Cc1nc2ccccc2c(C(=O)O)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C23 mock treatment 0.309 -0.00244 -0.2 0.307 0.00175 0.16 -0.0265 -0.1048 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 C24 positive control 0.084 -0.227 -18.31 0.08 -0.225 -20.45 -27.4082 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D01 compound treatment 0.331 0.0196 1.58 0.328 0.0227 2.07 2.5741 0.9911 2076814 Maybridge3_003235 N/C(=C(\NCc1c(F)cccc1Cl)/C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D02 compound treatment 0.334 0.0226 1.82 0.325 0.0198 1.79 2.5524 1.0 2076815 Maybridge3_003236 N/C(=N\O)/c1ccc(cc1)C2OCCO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D03 compound treatment 0.347 0.0356 2.86 0.339 0.0338 3.06 4.1912 0.9994 2076816 Maybridge3_003237 NC1=C(C#N)C(C(=C(O1)C2CC2)C#N)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D04 compound treatment 0.354 0.0426 3.43 0.346 0.0408 3.7 5.0391 0.9993 2076817 Maybridge3_003238 CSC(=C(C#N)C(=O)c1ccc(Cl)cc1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D05 compound treatment 0.333 0.0216 1.74 0.328 0.0227 2.07 2.688 0.9963 2076818 Maybridge3_003239 Cc1cc(C)n2nc(c(Br)c2n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D06 compound treatment 0.348 0.0366 2.94 0.341 0.0357 3.25 4.3765 0.9988 2076819 Maybridge3_003240 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2cccs2)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D07 compound treatment 0.327 0.0156 1.25 0.323 0.0177 1.61 2.0254 0.9923 2076820 Maybridge3_003241 CC(=N)Nc1cc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D08 compound treatment 0.363 0.0516 4.15 0.359 0.0537 4.88 6.386 0.9968 2076821 Maybridge3_003242 COc1ccc(cc1)C(=O)C(=C(SC)SC)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D09 compound treatment 0.329 0.0176 1.41 0.324 0.0187 1.7 2.2035 0.9958 2076822 Maybridge3_003243 CC(C)(C)c1cc2ncc(C#N)c(N)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D10 compound treatment 0.336 0.0246 1.98 0.323 0.0177 1.61 2.5379 0.9948 2076823 Maybridge3_003244 CS(=O)(=O)c1noc(c1C#N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D11 compound treatment 0.342 0.0306 2.46 0.342 0.0367 3.34 4.0991 0.9888 2076824 Maybridge3_003245 O=C(Nc1ccc(cc1)C2SCCS2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D12 compound treatment 0.322 0.0106 0.85 0.316 0.0107 0.98 1.2914 0.9977 1371807 Maybridge3_003246 CC(C)C(=O)Nc1cscc1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D13 compound treatment 0.319 0.00756 0.61 0.312 0.00675 0.61 0.8639 1.0 2076825 Maybridge3_003247 CSc1[nH]nc(c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D14 compound treatment 0.328 0.0166 1.33 0.323 0.0177 1.61 2.0824 0.9956 2076826 Maybridge3_003248 CC(=O)Nc1cscc1S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D15 compound treatment 0.34 0.0286 2.3 0.32 0.0147 1.34 2.5731 0.9668 2076827 Maybridge3_003249 CSc1nc(C)nc(c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D16 compound treatment 0.315 0.00356 0.29 0.305 -2.5E-4 -0.02 0.1868 0.6491 2076828 Maybridge3_003250 COC(=O)C1=C(CSC1)Nc2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D17 compound treatment 0.327 0.0156 1.25 0.327 0.0217 1.97 2.2822 0.9759 2076829 Maybridge3_003251 O=C(C(=C1SCCS1)C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D18 compound treatment 0.315 0.00356 0.29 0.311 0.00575 0.52 0.5719 0.9603 2076830 Maybridge3_003252 Cn1cc(Br)c(n1)c2cccc(NC(=O)c3ccccc3Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D19 compound treatment 0.325 0.0136 1.09 0.325 0.0198 1.79 2.0399 0.9718 2076831 Maybridge3_003253 CS/C(=C(/C#N)\C(=O)c1cccs1)/NCc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D20 compound treatment 0.327 0.0156 1.25 0.325 0.0198 1.79 2.1538 0.9847 2076832 Maybridge3_003254 CC(C)SC(=O)c1scc(c1Cl)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D21 compound treatment 0.314 0.00256 0.21 0.307 0.00175 0.16 0.2582 0.9916 2076833 Maybridge3_003255 CS/C(=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1)/NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D22 compound treatment 0.333 0.0216 1.74 0.328 0.0227 2.07 2.688 0.9963 2076834 Maybridge3_003256 Cn1ccnc1S(=O)(=O)/C(=C/c2ccccc2Cl)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D23 mock treatment 0.313 0.00156 0.13 0.309 0.00375 0.34 0.3297 0.9084 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 D24 positive control 0.085 -0.226 -18.23 0.09 -0.215 -19.54 -26.7094 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E01 compound treatment 0.322 0.0106 0.85 0.318 0.0127 1.16 1.4198 0.9885 2076835 Maybridge3_003257 Nc1nc(N)c(SC#N)cc1SC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E02 compound treatment 0.336 0.0246 1.98 0.325 0.0198 1.79 2.6663 0.9988 1519134 Maybridge3_003258 CCOC(=O)COc1ccc(cc1)C2C(=C(C)NC(=C2C#N)C)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E03 compound treatment 0.323 0.0116 0.93 0.313 0.00775 0.7 1.1558 0.9904 1471463 Maybridge3_003259 Clc1ccccc1C(=O)ON2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E04 compound treatment 0.331 0.0196 1.58 0.317 0.0118 1.07 1.8681 0.982 2076836 Maybridge3_003260 C(=C/c1ccccc1)\c2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E05 compound treatment 0.327 0.0156 1.25 0.319 0.0138 1.25 1.7687 1.0 1400566 Maybridge3_003261 CCc1cc2c(=O)c(coc2cc1O)c3nc4ccccc4[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E06 compound treatment 0.322 0.0106 0.85 0.315 0.00975 0.89 1.2272 0.9998 2076837 Maybridge3_003262 CCOC(=O)n1c(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E07 compound treatment 0.329 0.0176 1.41 0.318 0.0127 1.16 1.8184 0.995 1494804 Maybridge3_003263 CCOc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E08 compound treatment 0.332 0.0206 1.66 0.317 0.0118 1.07 1.925 0.9774 1539411 Maybridge3_003264 CCCCC1(O)C(=O)N(c2ccccc2)c3ccccc3C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E09 compound treatment 0.122 -0.189 -15.25 0.124 -0.181 -16.45 -22.4203 -0.9993 1489086 Maybridge3_003265 CCOC(=O)c1c(Cl)c2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E10 compound treatment 0.33 0.0186 1.49 0.32 0.0147 1.34 2.0037 0.9985 1034909 Maybridge3_003266 CC(=O)Nc1ccc(O)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E11 compound treatment 0.32 0.00856 0.69 0.315 0.00975 0.89 1.1134 0.9924 1202196 Maybridge3_003267 O=C(Cc1ccccc1)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E12 compound treatment 0.32 0.00856 0.69 0.309 0.00375 0.34 0.7282 0.9471 1377386 Maybridge3_003268 CN(C)CC1CCc2c(C1=O)c3ccccc3n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E13 compound treatment 0.328 0.0166 1.33 0.317 0.0118 1.07 1.6973 0.9939 1735299 Maybridge3_003269 Cc1cccc(c1)C(=O)Nc2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E14 compound treatment 0.322 0.0106 0.85 0.319 0.0138 1.25 1.484 0.9825 2076838 Maybridge3_003270 CN(C)c1nc(O)nc(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E15 compound treatment 0.327 0.0156 1.25 0.321 0.0158 1.43 1.8971 0.9978 1039961 Maybridge3_003271 CCS(=O)(=O)Cc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E16 compound treatment 0.343 0.0316 2.54 0.343 0.0377 3.43 4.2202 0.9892 2076839 Maybridge3_003272 CC1CN(CC(C)O1)C(=O)/C=C/c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E17 compound treatment 0.326 0.0146 1.17 0.315 0.00975 0.89 1.455 0.9904 2076840 Maybridge3_003273 COc1cc(/C=C/C(=O)NCC(=O)O)cc(Br)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E18 compound treatment 0.326 0.0146 1.17 0.322 0.0168 1.52 1.9043 0.9918 1419130 Maybridge3_003274 Cc1cc(NS(=O)(=O)c2cccs2)[nH]n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E19 compound treatment 0.32 0.00856 0.69 0.322 0.0168 1.52 1.5627 0.936 1439291 Maybridge3_003275 O=C(Oc1ccc2c3CCCc3c(=O)oc2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E20 compound treatment 0.322 0.0106 0.85 0.309 0.00375 0.34 0.8421 0.9192 1725656 Maybridge3_003276 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E21 compound treatment 0.327 0.0156 1.25 0.321 0.0158 1.43 1.8971 0.9978 2076841 Maybridge3_003277 C/C(=N\c1ccc(Cl)cc1)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E22 compound treatment 0.319 0.00756 0.61 0.315 0.00975 0.89 1.0564 0.9834 1152916 Maybridge3_003278 CC(=O)Nc1cc(nn1c2ccccc2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E23 mock treatment 0.307 -0.00444 -0.36 0.303 -0.00225 -0.2 -0.3971 -0.9648 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 E24 positive control 0.087 -0.224 -18.07 0.099 -0.206 -18.72 -26.0178 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F01 compound treatment 0.327 0.0156 1.25 0.322 0.0168 1.52 1.9612 0.9954 1378824 Maybridge3_003279 CC(C)(C)c1ccc(cc1)c2cc(N)[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F02 compound treatment 0.331 0.0196 1.58 0.326 0.0208 1.88 2.4457 0.9961 2076842 Maybridge3_003280 CC(C)N/C=C/1\C(=O)c2ccccc2N(C)S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F03 compound treatment 0.323 0.0116 0.93 0.34 0.0348 3.15 2.8888 0.8784 2076843 Maybridge3_003281 FC(F)(F)c1cc(nc2cc(nn12)c3ccco3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F04 compound treatment 0.327 0.0156 1.25 0.322 0.0168 1.52 1.9612 0.9954 2076844 Maybridge3_003282 Clc1cc(Cl)cc(N/C=C(\C#N)/S(=O)(=O)c2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F05 compound treatment 0.331 0.0196 1.58 0.322 0.0168 1.52 2.189 0.9998 2076845 Maybridge3_003283 CC(=O)Nc1cc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F06 compound treatment 0.337 0.0256 2.06 0.331 0.0257 2.34 3.1083 0.998 2076846 Maybridge3_003284 Fc1ccc(N/C=C(\C#N)/S(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F07 compound treatment 0.342 0.0306 2.46 0.333 0.0278 2.52 3.5214 0.9999 2076847 Maybridge3_003285 Nc1nc(Sc2ccc(Cl)cc2)c(C#N)c(c3ccco3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F08 compound treatment 0.355 0.0436 3.51 0.356 0.0508 4.61 5.7379 0.991 2076848 Maybridge3_003286 CSC(=C(C#N)C(=O)c1cccc(Cl)c1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F09 compound treatment 0.325 0.0136 1.09 0.328 0.0227 2.07 2.2325 0.9557 2076849 Maybridge3_003287 Clc1ccc(cc1)S(=O)(=O)/C(=C/NCc2ccccn2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F10 compound treatment 0.32 0.00856 0.69 0.319 0.0138 1.25 1.3701 0.9609 2076850 Maybridge3_003288 CS(=O)(=O)c1noc(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F11 compound treatment 0.33 0.0186 1.49 0.326 0.0208 1.88 2.3888 0.9934 2076851 Maybridge3_003289 Fc1ccc(SCC(=O)Nc2ccc(cc2)C3SCCS3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F12 compound treatment 0.322 0.0106 0.85 0.321 0.0158 1.43 1.6124 0.9692 2076852 Maybridge3_003290 CCSc1sc(C(=O)O)c(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F13 compound treatment 0.33 0.0186 1.49 0.325 0.0198 1.79 2.3246 0.9959 2076853 Maybridge3_003291 CC(=O)Nc1cc(n[nH]1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F14 compound treatment 0.327 0.0156 1.25 0.325 0.0198 1.79 2.1538 0.9847 2076854 Maybridge3_003292 C/C(=N\O)/CS(=O)(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F15 compound treatment 0.335 0.0236 1.9 0.331 0.0257 2.34 2.9944 0.9946 1219781 Maybridge3_003293 CSc1nc(N)n2nc(cc2n1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F16 compound treatment 0.326 0.0146 1.17 0.325 0.0198 1.79 2.0969 0.9788 2076855 Maybridge3_003294 COC(=O)C1=C(CSC1)Nc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F17 compound treatment 0.333 0.0216 1.74 0.33 0.0248 2.25 2.8164 0.9919 2076856 Maybridge3_003295 O=C(C(=C1SCCS1)C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F18 compound treatment 0.33 0.0186 1.49 0.328 0.0227 2.07 2.5172 0.9874 2076857 Maybridge3_003296 COC(=O)c1sc(SC)c(c1C)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F19 compound treatment 0.319 0.00756 0.61 0.312 0.00675 0.61 0.8639 1.0 2076858 Maybridge3_003297 CCOC(=O)Cn1nc(c(C#N)c1SC)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F20 compound treatment 0.324 0.0126 1.01 0.323 0.0177 1.61 1.8546 0.9749 1539986 Maybridge3_003298 CSc1nc2cc(nn2c(N)c1C#N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F21 compound treatment 0.326 0.0146 1.17 0.321 0.0158 1.43 1.8401 0.9952 2076859 Maybridge3_003299 Cc1cc(C)cc(N/C=C(\C#N)/S(=O)(=O)Cc2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F22 compound treatment 0.329 0.0176 1.41 0.327 0.0217 1.97 2.396 0.9866 1301446 Maybridge3_003300 CC(C)S(=O)(=O)c1cscc1NS(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F23 mock treatment 0.308 -0.00344 -0.28 0.304 -0.00125 -0.11 -0.276 -0.9225 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 F24 positive control 0.087 -0.224 -18.07 0.089 -0.216 -19.63 -26.6597 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G01 compound treatment 0.322 0.0106 0.85 0.317 0.0118 1.07 1.3556 0.9937 1425476 Maybridge3_003301 OC(=O)Cc1csc(NC(=O)CSc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G02 compound treatment 0.348 0.0366 2.94 0.351 0.0457 4.15 5.0184 0.9858 1141652 Maybridge3_003302 COC(=O)C1=C(C)NC2=C(C1c3ccccc3Cl)C(=O)CC(C)(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G03 compound treatment 0.323 0.0116 0.93 0.327 0.0217 1.97 2.0544 0.9412 1392756 Maybridge3_003303 O=C(COc1ccccc1)ON2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G04 compound treatment 0.36 0.0486 3.91 0.365 0.0597 5.42 6.6002 0.9871 1734390 Maybridge3_003304 Cc1cccc(CC(=O)c2c[nH]c3ccccc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G05 compound treatment 0.33 0.0186 1.49 0.335 0.0297 2.7 2.9665 0.9611 1395122 Maybridge3_003305 CC(=O)Oc1ccc2c(c1)oc(=O)c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G06 compound treatment 0.328 0.0166 1.33 0.341 0.0357 3.25 3.2377 0.9228 1271419 Maybridge3_003306 CCC(CO)NC(=O)c1cc(OC)c(OC)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G07 compound treatment 0.324 0.0126 1.01 0.333 0.0278 2.52 2.4965 0.9197 1654550 Maybridge3_003307 CCOC(=O)COc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G08 compound treatment 0.326 0.0146 1.17 0.328 0.0227 2.07 2.2894 0.9641 1516484 Maybridge3_003308 CCCCC1(O)C(=O)N(C)c2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G09 compound treatment 0.327 0.0156 1.25 0.339 0.0338 3.06 3.0524 0.9222 1305905 Maybridge3_003309 Cc1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G10 compound treatment 0.316 0.00456 0.37 0.316 0.0107 0.98 0.9498 0.9109 1491822 Maybridge3_003310 CNCCc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G11 compound treatment 0.318 0.00656 0.53 0.341 0.0357 3.25 2.6683 0.8116 1420239 Maybridge3_003311 O=C(NC1CCN(CC1)C(=O)c2ccco2)C3CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G12 compound treatment 0.319 0.00756 0.61 0.33 0.0248 2.25 2.0192 0.8675 2076860 Maybridge3_003312 FC(F)(F)Oc1ccc(/N=C/c2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G13 compound treatment 0.305 -0.00644 -0.52 0.329 0.0238 2.16 1.1578 0.5222 1921995 Maybridge3_003313 Clc1cccc(NC(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G14 compound treatment 0.317 0.00556 0.45 0.339 0.0338 3.06 2.483 0.802 2076861 Maybridge3_003314 Cn1nc(nc1O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G15 compound treatment 0.325 0.0136 1.09 0.349 0.0437 3.97 3.5804 0.8693 1077279 Maybridge3_003315 CC1(CC1(C)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G16 compound treatment 0.322 0.0106 0.85 0.344 0.0388 3.52 3.0886 0.8535 2076862 Maybridge3_003316 O=C(/C=C/c1cccc2ccccc12)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G17 compound treatment 0.328 0.0166 1.33 0.34 0.0348 3.15 3.1735 0.9267 2076863 Maybridge3_003317 C/C(=N\c1ccccc1C(F)(F)F)/c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G18 compound treatment 0.301 -0.0104 -0.84 0.348 0.0428 3.88 2.1496 0.5414 2076864 Maybridge3_003318 Fc1cccc(Nc2n[nH]c(=S)s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G19 compound treatment 0.318 0.00656 0.53 0.353 0.0478 4.33 3.4385 0.7875 1207073 Maybridge3_003319 CC(Nc1ccc(Cl)cc1)(C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G20 compound treatment 0.319 0.00756 0.61 0.346 0.0408 3.7 3.0462 0.8126 2076865 Maybridge3_003320 Clc1ccc(SCCS(=O)(=O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G21 compound treatment 0.325 0.0136 1.09 0.335 0.0297 2.7 2.6818 0.9206 1131674 Maybridge3_003321 CC(Nc1ccccc1)(C#N)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G22 compound treatment 0.326 0.0146 1.17 0.322 0.0168 1.52 1.9043 0.9918 1314413 Maybridge3_003322 COc1cccc(c1)c2cc3[nH]c(cc(=O)n3n2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G23 mock treatment 0.312 5.63E-4 0.05 0.303 -0.00225 -0.2 -0.1124 -0.5372 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 G24 positive control 0.089 -0.222 -17.91 0.085 -0.22 -19.99 -26.8025 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H01 compound treatment 0.337 0.0256 2.06 0.332 0.0267 2.43 3.1725 0.9966 1370357 Maybridge3_003323 NC1=C(C#N)C(C(=C(O1)C2CC2)C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H02 compound treatment 0.336 0.0246 1.98 0.33 0.0248 2.25 2.9872 0.998 2076866 Maybridge3_003324 Clc1ccccc1/C=C(\C#N)/S(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H03 compound treatment 0.347 0.0356 2.86 0.339 0.0338 3.06 4.1912 0.9994 2076867 Maybridge3_003325 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H04 compound treatment 0.334 0.0226 1.82 0.33 0.0248 2.25 2.8733 0.9945 2076868 Maybridge3_003326 Clc1ccccc1N/C=C(\C#N)/S(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H05 compound treatment 0.317 0.00556 0.45 0.318 0.0127 1.16 1.1351 0.9147 2076869 Maybridge3_003327 COc1ccccc1N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H06 compound treatment 0.327 0.0156 1.25 0.324 0.0187 1.7 2.0896 0.9887 2076870 Maybridge3_003328 CCOC(=O)/C(=C\Nc1ccc(F)cc1)/S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H07 compound treatment 0.332 0.0206 1.66 0.32 0.0147 1.34 2.1176 0.9944 1351121 Maybridge3_003329 CC(C)(C)c1cc2ncc(c(N)n2n1)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H08 compound treatment 0.327 0.0156 1.25 0.319 0.0138 1.25 1.7687 1.0 2076871 Maybridge3_003330 CS(=O)(=O)c1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H09 compound treatment 0.339 0.0276 2.22 0.337 0.0318 2.88 3.6073 0.9917 2076872 Maybridge3_003331 CC(=O)Nc1ccc(cc1)C2SCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H10 compound treatment 0.325 0.0136 1.09 0.328 0.0227 2.07 2.2325 0.9557 2076873 Maybridge3_003332 Cc1ccc(cc1)c2[nH]nc(c2C#N)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H11 compound treatment 0.317 0.00556 0.45 0.321 0.0158 1.43 1.3276 0.8862 2076874 Maybridge3_003333 Cc1cc(C)n2ncc(/C(=N/O)/N)c2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H12 compound treatment 0.339 0.0276 2.22 0.324 0.0187 1.7 2.7729 0.9914 2076875 Maybridge3_003334 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2nccs2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H13 compound treatment 0.32 0.00856 0.69 0.323 0.0177 1.61 1.6268 0.9283 2076876 Maybridge3_003335 CS(=O)(=O)c1[nH]nc(c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H14 compound treatment 0.346 0.0346 2.78 0.343 0.0377 3.43 4.391 0.9947 2076877 Maybridge3_003336 CSC(=C(C#N)C(=O)c1cccc(C)c1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H15 compound treatment 0.326 0.0146 1.17 0.314 0.00875 0.79 1.3908 0.982 1613210 Maybridge3_003337 CCOC(=O)c1c[nH]c2cc(nn2c1=O)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H16 compound treatment 0.335 0.0236 1.9 0.323 0.0177 1.61 2.481 0.9967 2076878 Maybridge3_003338 COC(=O)c1scc(c1n2cccc2)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H17 compound treatment 0.324 0.0126 1.01 0.323 0.0177 1.61 1.8546 0.9749 2076879 Maybridge3_003339 O=C(C1CC1)C(=C2SCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H18 compound treatment 0.325 0.0136 1.09 0.322 0.0168 1.52 1.8474 0.9868 2076880 Maybridge3_003340 Fc1ccccc1S(=O)(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H19 compound treatment 0.329 0.0176 1.41 0.324 0.0187 1.7 2.2035 0.9958 2076881 Maybridge3_003341 COC(=O)c1sc(SC)c(C#N)c1c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H20 compound treatment 0.323 0.0116 0.93 0.326 0.0208 1.88 1.9902 0.9472 1308477 Maybridge3_003342 CC(C)NC(=O)c1scc(c1Cl)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H21 compound treatment 0.315 0.00356 0.29 0.32 0.0147 1.34 1.1496 0.8396 2076882 Maybridge3_003343 CSc1n[nH]c(N)c1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H22 compound treatment 0.334 0.0226 1.82 0.331 0.0257 2.34 2.9375 0.9922 2076883 Maybridge3_003344 Cn1ccnc1S(=O)(=O)/C(=C/c2ccc(cc2)C(F)(F)F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H23 mock treatment 0.312 5.63E-4 0.05 0.308 0.00275 0.25 0.2085 0.822 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 H24 positive control 0.09 -0.221 -17.83 0.086 -0.219 -19.9 -26.6814 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I01 compound treatment 0.322 0.0106 0.85 0.323 0.0177 1.61 1.7407 0.9554 1156826 Maybridge3_003345 NC(=O)CNC(=O)CSc1ccccn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I02 compound treatment 0.331 0.0196 1.58 0.325 0.0198 1.79 2.3816 0.9979 1684929 Maybridge3_003346 C=CCC(NCc1ccccc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I03 compound treatment 0.339 0.0276 2.22 0.332 0.0267 2.43 3.2864 0.999 1538526 Maybridge3_003347 NC(=O)CNC(=O)COc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I04 compound treatment 0.327 0.0156 1.25 0.319 0.0138 1.25 1.7687 1.0 1519654 Maybridge3_003348 CCN(CC)C(=O)c1cc(O)cc(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I05 compound treatment 0.336 0.0246 1.98 0.327 0.0217 1.97 2.7946 1.0 1917300 Maybridge3_003349 N=C1SC2CS(=O)(=O)CC2N1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I06 compound treatment 0.326 0.0146 1.17 0.324 0.0187 1.7 2.0327 0.9835 1053212 Maybridge3_003350 CNc1ccc(cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I07 compound treatment 0.333 0.0216 1.74 0.332 0.0267 2.43 2.9447 0.9865 1463264 Maybridge3_003351 CC(Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I08 compound treatment 0.333 0.0216 1.74 0.33 0.0248 2.25 2.8164 0.9919 2076884 Maybridge3_003352 CCOC(=O)c1c(C)n[nH]c1/N=C/c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I09 compound treatment 0.322 0.0106 0.85 0.317 0.0118 1.07 1.3556 0.9937 1610357 Maybridge3_003353 O=C(N1CCCC1)C2(CC3CC4C2)CC(C3)CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I10 compound treatment 0.344 0.0326 2.62 0.335 0.0297 2.7 3.7636 0.9999 1486810 Maybridge3_003354 CCOC(=O)c1cc2c(cn1)[nH]c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I11 compound treatment 0.336 0.0246 1.98 0.328 0.0227 2.07 2.8588 0.9998 1586479 Maybridge3_003355 Cc1ccc(cc1)C(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I12 compound treatment 0.319 0.00756 0.61 0.312 0.00675 0.61 0.8639 1.0 2076885 Maybridge3_003356 CSc1nc(N)n(n1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I13 compound treatment 0.336 0.0246 1.98 0.323 0.0177 1.61 2.5379 0.9948 1549605 Maybridge3_003357 COc1ccc(NC(=O)c2ccc(OC)c(OC)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I14 compound treatment 0.323 0.0116 0.93 0.32 0.0147 1.34 1.6051 0.9842 2076886 Maybridge3_003358 Oc1nc(n[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I15 compound treatment 0.323 0.0116 0.93 0.319 0.0138 1.25 1.5409 0.9896 1623834 Maybridge3_003359 COc1cccc(C(=O)O)c1OCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I16 compound treatment 0.321 0.00956 0.77 0.324 0.0187 1.7 1.748 0.9357 1577196 Maybridge3_003360 CCOC(=O)c1ccc(N2CCCCC2)c(N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I17 compound treatment 0.326 0.0146 1.17 0.32 0.0147 1.34 1.7759 0.9978 2076887 Maybridge3_003361 COC1OC(=O)c2cc(OC)cc(OC)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I18 compound treatment 0.321 0.00956 0.77 0.322 0.0168 1.52 1.6196 0.9503 1425053 Maybridge3_003362 O=S(=O)(CCN1CCOCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I19 compound treatment 0.334 0.0226 1.82 0.32 0.0147 1.34 2.2315 0.9887 1426352 Maybridge3_003363 CCCCc1c(O)[nH]c2n(ncc2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I20 compound treatment 0.334 0.0226 1.82 0.321 0.0158 1.43 2.2956 0.993 1646337 Maybridge3_003364 O=c1cc([nH]c2cc(nn12)c3cccs3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I21 compound treatment 0.319 0.00756 0.61 0.312 0.00675 0.61 0.8639 1.0 2076888 Maybridge3_003365 C/C(=N\c1ccc(Cl)cc1)/c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I22 compound treatment 0.326 0.0146 1.17 0.324 0.0187 1.7 2.0327 0.9835 1475476 Maybridge3_003366 Cc1nn(c2nc(O)cc(C)c12)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I23 mock treatment 0.312 5.63E-4 0.05 0.307 0.00175 0.16 0.1444 0.8739 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 I24 positive control 0.09 -0.221 -17.83 0.085 -0.22 -19.99 -26.7456 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J01 compound treatment 0.331 0.0196 1.58 0.328 0.0227 2.07 2.5741 0.9911 1204610 Maybridge3_003367 CC(C)(C)C(=O)Nc1c(Cl)c(nn1c2ccccc2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J02 compound treatment 0.332 0.0206 1.66 0.323 0.0177 1.61 2.3101 0.9999 2076889 Maybridge3_003368 CSc1nc(nc(c2ccco2)c1C#N)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J03 compound treatment 0.331 0.0196 1.58 0.321 0.0158 1.43 2.1248 0.9988 1454802 Maybridge3_003369 Cn1nc(cc1N)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J04 compound treatment 0.33 0.0186 1.49 0.324 0.0187 1.7 2.2604 0.9979 2076890 Maybridge3_003370 CSc1c(C(=O)N)c(nn1C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J05 compound treatment 0.321 0.00956 0.77 0.31 0.00475 0.43 0.8494 0.9624 2076891 Maybridge3_003371 COc1c(Cl)scc1C(=O)NCc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J06 compound treatment 0.333 0.0216 1.74 0.326 0.0208 1.88 2.5596 0.9992 1209649 Maybridge3_003372 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J07 compound treatment 0.322 0.0106 0.85 0.32 0.0147 1.34 1.5482 0.976 2076892 Maybridge3_003373 N/C(=N\O)/c1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J08 compound treatment 0.316 0.00456 0.37 0.307 0.00175 0.16 0.3721 0.9297 2076893 Maybridge3_003374 CSc1nn(c(N)c1S(=O)(=O)c2ccc(Cl)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J09 compound treatment 0.329 0.0176 1.41 0.319 0.0138 1.25 1.8826 0.9981 1221373 Maybridge3_003375 Nc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J10 compound treatment 0.319 0.00756 0.61 0.316 0.0107 0.98 1.1206 0.9742 2076894 Maybridge3_003376 O=S(=O)(Cc1cccc(C#N)c1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J11 compound treatment 0.324 0.0126 1.01 0.315 0.00975 0.89 1.3411 0.9978 1153118 Maybridge3_003377 COCc1cc(=O)n2nc(cc2[nH]1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J12 compound treatment 0.325 0.0136 1.09 0.312 0.00675 0.61 1.2055 0.9627 2076895 Maybridge3_003378 CCOC(OCC)c1ccc(/C=C(\C#N)/S(=O)(=O)c2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J13 compound treatment 0.378 0.0666 5.36 0.369 0.0638 5.79 7.8819 0.9993 2076896 Maybridge3_003379 CSC(=C(C#N)C(=O)c1ccccc1Cl)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J14 compound treatment 0.333 0.0216 1.74 0.323 0.0177 1.61 2.3671 0.9993 2076897 Maybridge3_003380 CCCS(=O)(=O)/C(=C/Nc1ccccn1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J15 compound treatment 0.319 0.00756 0.61 0.315 0.00975 0.89 1.0564 0.9834 2076898 Maybridge3_003381 CC(C)(C)C(=O)C(=C1SCCCS1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J16 compound treatment 0.33 0.0186 1.49 0.319 0.0138 1.25 1.9395 0.996 2076899 Maybridge3_003382 CCOC(=O)Cn1c(=O)c2ccsc2c3c(C#N)c(SC)sc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J17 compound treatment 0.317 0.00556 0.45 0.314 0.00875 0.79 0.8784 0.9633 2076900 Maybridge3_003383 CC(C)(C)C(=O)C(=C1SCCS1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J18 compound treatment 0.326 0.0146 1.17 0.318 0.0127 1.16 1.6476 1.0 2076901 Maybridge3_003384 COC(=O)c1scc(c1NC(=O)c2ccccc2Cl)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J19 compound treatment 0.331 0.0196 1.58 0.327 0.0217 1.97 2.5099 0.9937 2076902 Maybridge3_003385 COC(=O)c1scc(c1N)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J20 compound treatment 0.325 0.0136 1.09 0.321 0.0158 1.43 1.7832 0.9912 1404620 Maybridge3_003386 CS(=O)(=O)c1csc(C(=O)NCc2cccnc2)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J21 compound treatment 0.337 0.0256 2.06 0.324 0.0187 1.7 2.659 0.9955 2076903 Maybridge3_003387 Cc1cc(C)nc(N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J22 compound treatment 0.322 0.0106 0.85 0.32 0.0147 1.34 1.5482 0.976 1225987 Maybridge3_003388 CC(C)S(=O)(=O)c1cscc1NC(=O)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J23 mock treatment 0.317 0.00556 0.45 0.303 -0.00225 -0.2 0.1723 0.35 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 J24 positive control 0.09 -0.221 -17.83 0.086 -0.219 -19.9 -26.6814 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K01 compound treatment 0.322 0.0106 0.85 0.317 0.0118 1.07 1.3556 0.9937 2076904 Maybridge3_003389 CCOC(=O)Cc1csc(NC(=O)CSc2ccccn2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K02 compound treatment 0.324 0.0126 1.01 0.317 0.0118 1.07 1.4695 0.9997 1509883 Maybridge3_003390 Cc1ccc(o1)C(CC=C)NCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K03 compound treatment 0.329 0.0176 1.41 0.322 0.0168 1.52 2.0751 0.9993 1714615 Maybridge3_003391 CCOC(=O)c1ccc(NC(=O)CS(=O)(=O)C(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K04 compound treatment 0.33 0.0186 1.49 0.323 0.0177 1.61 2.1962 0.9993 2076905 Maybridge3_003392 CCCC(C1C(=O)CC(C)(C)CC1=O)C2C(=O)CC(C)(C)CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K05 compound treatment 0.333 0.0216 1.74 0.327 0.0217 1.97 2.6238 0.998 1367596 Maybridge3_003393 Cc1ccc2oc(cc(=O)c2c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K06 compound treatment 0.329 0.0176 1.41 0.32 0.0147 1.34 1.9468 0.9996 1005727 Maybridge3_003394 OC(=O)C(Cc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K07 compound treatment 0.366 0.0546 4.39 0.36 0.0548 4.97 6.621 0.9981 2076906 Maybridge3_003395 O=C1C(C(=O)c2cc3ccccc3cc12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K08 compound treatment 0.322 0.0106 0.85 0.327 0.0217 1.97 1.9975 0.9292 1700513 Maybridge3_003396 COc1ccc(cc1OC)c2c(C)n[nH]c2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K09 compound treatment 0.326 0.0146 1.17 0.317 0.0118 1.07 1.5834 0.9989 1447029 Maybridge3_003397 COc1ccccc1CC(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K10 compound treatment 0.32 0.00856 0.69 0.314 0.00875 0.79 1.0492 0.9975 1057502 Maybridge3_003398 CC1(CC(=C(C#N)C(=O)N1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K11 compound treatment 0.335 0.0236 1.9 0.321 0.0158 1.43 2.3526 0.9903 1511939 Maybridge3_003399 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K12 compound treatment 0.324 0.0126 1.01 0.322 0.0168 1.52 1.7904 0.9804 2076907 Maybridge3_003400 Cc1ccc(cc1)c2cncnc2NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K13 compound treatment 0.327 0.0156 1.25 0.318 0.0127 1.16 1.7045 0.9992 1421340 Maybridge3_003401 COc1ccc(CNC(=O)c2cc(OC)c(OC)c(OC)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K14 compound treatment 0.323 0.0116 0.93 0.32 0.0147 1.34 1.6051 0.9842 2076908 Maybridge3_003402 Nc1ncnc(SCc2cccc(C#N)c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K15 compound treatment 0.321 0.00956 0.77 0.316 0.0107 0.98 1.2345 0.9931 2076909 Maybridge3_003403 COc1ccc2c(OC(=O)C)coc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K16 compound treatment 0.374 0.0626 5.04 0.365 0.0597 5.42 7.3974 0.9993 1404830 Maybridge3_003404 COc1cc2CCN=C(c3ccccc3N)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K17 compound treatment 0.317 0.00556 0.45 0.313 0.00775 0.7 0.8142 0.9762 1024059 Maybridge3_003405 COc1ccccc1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K18 compound treatment 0.321 0.00956 0.77 0.309 0.00375 0.34 0.7852 0.9326 2076910 Maybridge3_003406 Clc1ccc(cc1)S(=O)(=O)CCS(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K19 compound treatment 0.322 0.0106 0.85 0.315 0.00975 0.89 1.2272 0.9998 1326383 Maybridge3_003407 COC(=O)C1CC2CC(CC(C(=O)OC)C32SCCS3)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K20 compound treatment 0.324 0.0126 1.01 0.317 0.0118 1.07 1.4695 0.9997 2076911 Maybridge3_003408 CCOC(=O)C1=C(Nc2ccc(F)cc2)C(=O)N(C1)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K21 compound treatment 0.152 -0.159 -12.84 0.147 -0.158 -14.36 -19.2358 -0.9984 2076912 Maybridge3_003409 O=C(Oc1cccc2C(=O)C=CC(=O)c12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K22 compound treatment 0.349 0.0376 3.02 0.34 0.0348 3.15 4.3693 0.9998 2076913 Maybridge3_003410 N/C(=C(/N=C/c1c(F)cccc1Cl)\C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K23 mock treatment 0.317 0.00556 0.45 0.305 -2.5E-4 -0.02 0.3007 0.6704 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 K24 positive control 0.092 -0.219 -17.67 0.087 -0.218 -19.81 -26.5033 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L01 compound treatment 0.369 0.0576 4.64 0.363 0.0578 5.24 6.9843 0.9981 2076914 Maybridge3_003411 NC1=C(C#N)C(C(=C(O1)C2CC2)C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L02 compound treatment 0.332 0.0206 1.66 0.325 0.0198 1.79 2.4385 0.9992 1325572 Maybridge3_003412 Cc1cc(O)nc2n(C)nc(c3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L03 compound treatment 0.336 0.0246 1.98 0.327 0.0217 1.97 2.7946 1.0 1394349 Maybridge3_003413 CCOC(=O)c1c[nH]c2cc(nn2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L04 compound treatment 0.334 0.0226 1.82 0.324 0.0187 1.7 2.4882 0.9995 1485401 Maybridge3_003414 CSc1n[nH]c(NC(=O)c2cccs2)c1S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L05 compound treatment 0.329 0.0176 1.41 0.321 0.0158 1.43 2.0109 1.0 2076915 Maybridge3_003415 COc1c(Cl)scc1C(=O)Nc2cc(OC)ccc2OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L06 compound treatment 0.325 0.0136 1.09 0.318 0.0127 1.16 1.5906 0.9996 2076916 Maybridge3_003416 Cc1n[nH]cc1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L07 compound treatment 0.328 0.0166 1.33 0.329 0.0238 2.16 2.4675 0.9734 2076917 Maybridge3_003417 COc1c(Br)scc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L08 compound treatment 0.325 0.0136 1.09 0.323 0.0177 1.61 1.9115 0.9821 2076918 Maybridge3_003418 N#Cc1cccc(CSc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L09 compound treatment 0.327 0.0156 1.25 0.323 0.0177 1.61 2.0254 0.9923 2076919 Maybridge3_003419 Clc1ccc(cc1)S(=O)(=O)/C(=C/NCc2ccco2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L10 compound treatment 0.365 0.0536 4.31 0.361 0.0558 5.06 6.6282 0.9968 2076920 Maybridge3_003420 CSC(=C1C(=O)c2ccccc2N(C)S1(=O)=O)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L11 compound treatment 0.33 0.0186 1.49 0.327 0.0217 1.97 2.453 0.9906 1354457 Maybridge3_003421 COCc1cc(=O)n2nc(cc2[nH]1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L12 compound treatment 0.325 0.0136 1.09 0.32 0.0147 1.34 1.719 0.9949 1541841 Maybridge3_003422 CSc1sc(C(=O)NC(C)C)c(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L13 compound treatment 0.367 0.0556 4.47 0.363 0.0578 5.24 6.8705 0.9969 1469401 Maybridge3_003423 COc1cccc(c1)C(=O)C(=C(SC)SC)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L14 compound treatment 0.328 0.0166 1.33 0.322 0.0168 1.52 2.0182 0.9979 2076921 Maybridge3_003424 CS(=O)(=O)/C(=C/Nc1cccnc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L15 compound treatment 0.328 0.0166 1.33 0.325 0.0198 1.79 2.2107 0.9894 2076922 Maybridge3_003425 O=C(C1CC1)C(=C2SCCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L16 compound treatment 0.326 0.0146 1.17 0.318 0.0127 1.16 1.6476 1.0 2076923 Maybridge3_003426 CCCS(=O)(=O)c1cnc2cc(nn2c1N)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L17 compound treatment 0.324 0.0126 1.01 0.321 0.0158 1.43 1.7262 0.9857 2076924 Maybridge3_003427 CSc1c(C#N)c(nn1C)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L18 compound treatment 0.346 0.0346 2.78 0.341 0.0357 3.25 4.2626 0.9971 2076925 Maybridge3_003428 COc1ccc(cc1)c2nc(N)nc(SC)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L19 compound treatment 0.345 0.0336 2.7 0.339 0.0338 3.06 4.0773 0.998 2076926 Maybridge3_003429 CSC(=C(C#N)C(=O)C1CC1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L20 compound treatment 0.323 0.0116 0.93 0.318 0.0127 1.16 1.4767 0.9942 2076927 Maybridge3_003430 ONC(=O)CS(=O)(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L21 compound treatment 0.329 0.0176 1.41 0.318 0.0127 1.16 1.8184 0.995 2076928 Maybridge3_003431 CSc1nc(SC)c(C#N)c(n1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L22 compound treatment 0.354 0.0426 3.43 0.353 0.0478 4.33 5.4884 0.9932 1666779 Maybridge3_003432 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L23 mock treatment 0.318 0.00656 0.53 0.306 7.5E-4 0.07 0.4218 0.7917 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 L24 positive control 0.091 -0.22 -17.75 0.088 -0.217 -19.72 -26.4961 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M01 compound treatment 0.32 0.00856 0.69 0.316 0.0107 0.98 1.1775 0.9855 1251602 Maybridge3_003433 CCOC(=O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M02 compound treatment 0.322 0.0106 0.85 0.316 0.0107 0.98 1.2914 0.9977 1642343 Maybridge3_003434 OCCNC1(CC=C)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M03 compound treatment 0.327 0.0156 1.25 0.32 0.0147 1.34 1.8329 0.9995 1627244 Maybridge3_003435 COc1cccc(c1)C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M04 compound treatment 0.447 0.136 10.92 0.44 0.135 12.23 16.368 0.9984 2076929 Maybridge3_003436 COc1cc2ccccc2nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M05 compound treatment 0.331 0.0196 1.58 0.33 0.0248 2.25 2.7025 0.9849 1426336 Maybridge3_003437 Cc1ccc2oc(cc(=O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M06 compound treatment 0.335 0.0236 1.9 0.331 0.0257 2.34 2.9944 0.9946 1353545 Maybridge3_003438 C1CCN(CC1)c2cc(nc3ccccc23)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M07 compound treatment 0.354 0.0426 3.43 0.348 0.0428 3.88 5.1675 0.9981 1008073 Maybridge3_003439 CCC(=O)C1C(=O)c2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M08 compound treatment 0.33 0.0186 1.49 0.321 0.0158 1.43 2.0679 0.9998 1211791 Maybridge3_003440 COc1cc2CC(=O)NC(c3ccc(Cl)cc3Cl)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M09 compound treatment 0.354 0.0426 3.43 0.343 0.0377 3.43 4.8465 1.0 1208831 Maybridge3_003441 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)NC(=O)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M10 compound treatment 0.326 0.0146 1.17 0.32 0.0147 1.34 1.7759 0.9978 1232177 Maybridge3_003442 CCCc1nc(O)cc2cc(OC)c(OC)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M11 compound treatment 0.329 0.0176 1.41 0.319 0.0138 1.25 1.8826 0.9981 1226076 Maybridge3_003443 Cc1ccc(cc1)C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M12 compound treatment 0.341 0.0296 2.38 0.334 0.0288 2.61 3.5286 0.9989 1401804 Maybridge3_003444 CN(C)C(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M13 compound treatment 0.318 0.00656 0.53 0.311 0.00575 0.52 0.7427 1.0 1539451 Maybridge3_003445 CC(C)NC(=O)c1ccccc1c2ccccc2C(=O)NC(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M14 compound treatment 0.318 0.00656 0.53 0.313 0.00775 0.7 0.8711 0.9901 2076930 Maybridge3_003446 Oc1ccnc(SCc2cccc(C#N)c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M15 compound treatment 0.315 0.00356 0.29 0.314 0.00875 0.79 0.7645 0.9053 2076931 Maybridge3_003447 COC(=O)COc1cc(OC)ccc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M16 compound treatment 0.319 0.00756 0.61 0.308 0.00275 0.25 0.6071 0.9225 1007288 Maybridge3_003448 CCOC(=O)C(=C1CCCC1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M17 compound treatment 0.322 0.0106 0.85 0.318 0.0127 1.16 1.4198 0.9885 1155355 Maybridge3_003449 OC(=O)c1ccnc(c1)c2cc(ccn2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M18 compound treatment 0.325 0.0136 1.09 0.318 0.0127 1.16 1.5906 0.9996 2076932 Maybridge3_003450 Cc1cc(NC(=O)c2ccccc2)n(n1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M19 compound treatment 0.311 -4.37E-4 -0.04 0.311 0.00575 0.52 0.3442 0.6579 2076933 Maybridge3_003451 N#Cc1ccccc1SCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M20 compound treatment 0.313 0.00156 0.13 0.31 0.00475 0.43 0.3938 0.8769 1228174 Maybridge3_003452 CCCCc1c(C)[nH]c2cc(nn2c1=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M21 compound treatment 0.321 0.00956 0.77 0.317 0.0118 1.07 1.2987 0.9872 2076934 Maybridge3_003453 Cc1ccc(cc1)C(=O)OC2=CC(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M22 compound treatment 0.321 0.00956 0.77 0.313 0.00775 0.7 1.0419 0.999 2076935 Maybridge3_003454 CC(C)(C)c1cc2[nH]c(cc(=O)n2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M23 mock treatment 0.304 -0.00744 -0.6 0.303 -0.00225 -0.2 -0.5679 -0.8975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 M24 positive control 0.094 -0.217 -17.51 0.088 -0.217 -19.72 -26.3253 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N01 compound treatment 0.345 0.0336 2.7 0.335 0.0297 2.7 3.8206 1.0 1158404 Maybridge3_003455 Cc1cc(=O)n2nc(cc2[nH]1)c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N02 compound treatment 0.325 0.0136 1.09 0.321 0.0158 1.43 1.7832 0.9912 1139757 Maybridge3_003456 COCc1cc(O)nc2n(C)nc(c3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N03 compound treatment 0.322 0.0106 0.85 0.318 0.0127 1.16 1.4198 0.9885 1253876 Maybridge3_003457 CCOC(=O)c1c[nH]c2cc(nn2c1=O)c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N04 compound treatment 0.328 0.0166 1.33 0.322 0.0168 1.52 2.0182 0.9979 1688506 Maybridge3_003458 Clc1ccc(cc1)c2nc(CS(=O)(=O)c3ccccn3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N05 compound treatment 0.323 0.0116 0.93 0.319 0.0138 1.25 1.5409 0.9896 1559491 Maybridge3_003459 CC(C)(C)c1ccc(cc1)c2cc(NC(=O)c3ccccc3F)[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N06 compound treatment 0.329 0.0176 1.41 0.328 0.0227 2.07 2.4602 0.983 1517481 Maybridge3_003460 Clc1ccc(SCc2nc(CS(=O)(=O)c3ccccn3)no2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N07 compound treatment 0.33 0.0186 1.49 0.326 0.0208 1.88 2.3888 0.9934 1063650 Maybridge3_003461 Cc1ccc(cc1)S(=O)(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N08 compound treatment 0.325 0.0136 1.09 0.325 0.0198 1.79 2.0399 0.9718 2076936 Maybridge3_003462 N/C(=N\O)/c1cccc(CSc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N09 compound treatment 0.333 0.0216 1.74 0.331 0.0257 2.34 2.8806 0.9893 2076937 Maybridge3_003463 Cc1ncc(c(N)n1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N10 compound treatment 0.332 0.0206 1.66 0.325 0.0198 1.79 2.4385 0.9992 2076938 Maybridge3_003464 CS/C(=C(/C#N)\C(=O)C1CC1)/NCc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N11 compound treatment 0.344 0.0326 2.62 0.335 0.0297 2.7 3.7636 0.9999 1365727 Maybridge3_003465 CCOC(=O)C1SC(C(C#N)C1(O)c2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N12 compound treatment 0.319 0.00756 0.61 0.313 0.00775 0.7 0.928 0.9974 1436607 Maybridge3_003466 CSc1sc(C(=O)NCC2CC2)c(c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N13 compound treatment 0.329 0.0176 1.41 0.322 0.0168 1.52 2.0751 0.9993 2076939 Maybridge3_003467 CSc1[nH]nc(c1C#N)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N14 compound treatment 0.334 0.0226 1.82 0.33 0.0248 2.25 2.8733 0.9945 2076940 Maybridge3_003468 CC(C)(C)S(=O)(=O)/C(=C/Nc1ncccn1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N15 compound treatment 0.323 0.0116 0.93 0.32 0.0147 1.34 1.6051 0.9842 2076941 Maybridge3_003469 Cn1nc(cc1N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N16 compound treatment 0.319 0.00756 0.61 0.315 0.00975 0.89 1.0564 0.9834 2076942 Maybridge3_003470 CSc1scc(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N17 compound treatment 0.319 0.00756 0.61 0.318 0.0127 1.16 1.249 0.955 2076943 Maybridge3_003471 Clc1ccc(cc1)S(=O)(=O)C(=C2SCCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N18 compound treatment 0.351 0.0396 3.19 0.347 0.0418 3.79 4.9324 0.9963 1525961 Maybridge3_003472 CSc1nc2cc(nn2c(N)c1S(=O)(=O)c3ccc(Cl)cc3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N19 compound treatment 0.334 0.0226 1.82 0.326 0.0208 1.88 2.6166 0.9998 2076944 Maybridge3_003473 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2ccccc2)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N20 compound treatment 0.322 0.0106 0.85 0.32 0.0147 1.34 1.5482 0.976 1729009 Maybridge3_003474 CC(C)S(=O)(=O)c1cscc1NC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N21 compound treatment 0.327 0.0156 1.25 0.322 0.0168 1.52 1.9612 0.9954 2076945 Maybridge3_003475 CSc1nc(SC)c(C#N)c(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N22 compound treatment 0.301 -0.0104 -0.84 0.3 -0.00525 -0.48 -0.9313 -0.9639 1248518 Maybridge3_003476 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N23 mock treatment 0.312 5.63E-4 0.05 0.307 0.00175 0.16 0.1444 0.8739 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 N24 positive control 0.091 -0.22 -17.75 0.088 -0.217 -19.72 -26.4961 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O01 compound treatment 0.338 0.0266 2.14 0.334 0.0288 2.61 3.3578 0.9951 1517988 Maybridge3_003477 N#Cc1cc(Oc2cccnc2)c(Oc3cccnc3)cc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O02 compound treatment 0.334 0.0226 1.82 0.327 0.0217 1.97 2.6808 0.9991 1623036 Maybridge3_003478 COc1cccc(O)c1C(=O)NCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O03 compound treatment 0.52 0.209 16.79 0.518 0.213 19.31 25.5311 0.9976 1070047 Maybridge3_003479 CC1(C)NC(C(=O)O)C(C)(C)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O04 compound treatment 0.335 0.0236 1.9 0.327 0.0217 1.97 2.7377 0.9998 1152629 Maybridge3_003480 OC(=O)CCc1ccc(OCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O05 compound treatment 0.325 0.0136 1.09 0.322 0.0168 1.52 1.8474 0.9868 2076946 Maybridge3_003481 COCn1nnc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O06 compound treatment 0.386 0.0746 6.0 0.372 0.0668 6.06 8.53 1.0 1348155 Maybridge3_003482 CC(=O)Nc1sc-2c(CCc3ccccc23)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O07 compound treatment 0.331 0.0196 1.58 0.325 0.0198 1.79 2.3816 0.9979 1038934 Maybridge3_003483 Cc1cc(C)c(CN)cc1CN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O08 compound treatment 0.358 0.0466 3.75 0.352 0.0468 4.24 5.652 0.9981 2076947 Maybridge3_003484 CC/1=NOC(=O)\C1=C/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O09 compound treatment 0.332 0.0206 1.66 0.33 0.0248 2.25 2.7594 0.9887 2076948 Maybridge3_003485 CC/1(C)C2CCC(C2)\C1=C\CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O10 compound treatment 0.326 0.0146 1.17 0.322 0.0168 1.52 1.9043 0.9918 1469772 Maybridge3_003486 COc1ccc(cc1OC)c2cn[nH]c2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O11 compound treatment 0.325 0.0136 1.09 0.315 0.00975 0.89 1.3981 0.9946 2076949 Maybridge3_003487 FC(F)(F)c1cccc(c1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O12 compound treatment 0.337 0.0256 2.06 0.334 0.0288 2.61 3.3009 0.9931 2076950 Maybridge3_003488 CC(C)(C)c1ccc(cc1)C(=O)c2ncc[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O13 compound treatment 0.698 0.387 31.13 0.687 0.382 34.65 46.5138 0.9986 1694243 Maybridge3_003489 CN(CCO)c1ccc(cc1)C(=O)c2ccc(cc2)N(C)CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O14 compound treatment 0.337 0.0256 2.06 0.327 0.0217 1.97 2.8516 0.9998 2076951 Maybridge3_003490 CC1CN(CC(C)O1)S(=O)(=O)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O15 compound treatment 0.328 0.0166 1.33 0.323 0.0177 1.61 2.0824 0.9956 1039548 Maybridge3_003491 CCC(=O)c1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O16 compound treatment 0.332 0.0206 1.66 0.331 0.0257 2.34 2.8236 0.9857 1365143 Maybridge3_003492 OC(=O)c1cc2ccccc2cc1OC(=O)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O17 compound treatment 0.326 0.0146 1.17 0.322 0.0168 1.52 1.9043 0.9918 1024058 Maybridge3_003493 Clc1ccccc1c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O18 compound treatment 0.323 0.0116 0.93 0.321 0.0158 1.43 1.6693 0.9784 2076952 Maybridge3_003494 Cc1cc2[nH]c(cc(=O)n2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O19 compound treatment 0.326 0.0146 1.17 0.327 0.0217 1.97 2.2252 0.9691 2076953 Maybridge3_003495 NC(=O)c1ccccc1SCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O20 compound treatment 0.325 0.0136 1.09 0.319 0.0138 1.25 1.6548 0.9978 1469249 Maybridge3_003496 Clc1ccc(cc1)S(=O)(=O)CC(N2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O21 compound treatment 0.328 0.0166 1.33 0.322 0.0168 1.52 2.0182 0.9979 2076954 Maybridge3_003497 CN(C)C(=O)Oc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O22 compound treatment 0.332 0.0206 1.66 0.328 0.0227 2.07 2.6311 0.994 2076955 Maybridge3_003498 Cc1cc(=O)n2nc(cc2[nH]1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O23 mock treatment 0.316 0.00456 0.37 0.31 0.00475 0.43 0.5647 0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 O24 positive control 0.093 -0.218 -17.59 0.089 -0.216 -19.63 -26.318 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P01 compound treatment 0.338 0.0266 2.14 0.328 0.0227 2.07 2.9727 0.9998 2076956 Maybridge3_003499 CC(C)(C)c1ccc(cc1)C(=O)/C=C/2\NC(=O)CS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P02 compound treatment 0.572 0.261 20.98 0.55 0.245 22.22 30.5459 0.9996 2076957 Maybridge3_003500 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccccc2Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P03 compound treatment 0.335 0.0236 1.9 0.329 0.0238 2.16 2.8661 0.998 1706986 Maybridge3_003501 CCOC(=O)c1c[nH]c2cc(nn2c1=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P04 compound treatment 0.329 0.0176 1.41 0.324 0.0187 1.7 2.2035 0.9958 2076958 Maybridge3_003502 N#CCSc1nc2ccccc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P05 compound treatment 0.323 0.0116 0.93 0.319 0.0138 1.25 1.5409 0.9896 2076959 Maybridge3_003503 CC(=O)Nc1cc(C)nn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P06 compound treatment 0.342 0.0306 2.46 0.339 0.0338 3.06 3.9065 0.9941 2076960 Maybridge3_003504 CN1c2ccccc2C(=O)/C(=C\Nc3ccc(F)cc3F)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P07 compound treatment 0.345 0.0336 2.7 0.338 0.0328 2.97 4.0131 0.9989 2076961 Maybridge3_003505 COc1c(Br)scc1C(=O)Nc2cc(OC)c(OC)c(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P08 compound treatment 0.345 0.0336 2.7 0.342 0.0367 3.34 4.2699 0.9945 2076962 Maybridge3_003506 CC1CN(CC(C)O1)C(=O)c2scc(c2C)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P09 compound treatment 0.325 0.0136 1.09 0.323 0.0177 1.61 1.9115 0.9821 2076963 Maybridge3_003507 Nc1ncc(c(N)n1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P10 compound treatment 0.322 0.0106 0.85 0.319 0.0138 1.25 1.484 0.9825 1330815 Maybridge3_003508 COc1c(Br)scc1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P11 compound treatment 0.32 0.00856 0.69 0.315 0.00975 0.89 1.1134 0.9924 2076964 Maybridge3_003509 Cc1cc(=O)n2nc(cc2[nH]1)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P12 compound treatment 0.325 0.0136 1.09 0.318 0.0127 1.16 1.5906 0.9996 1689948 Maybridge3_003510 CSc1sc(C(=O)N2CCCCC2)c(c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P13 compound treatment 0.323 0.0116 0.93 0.321 0.0158 1.43 1.6693 0.9784 2076965 Maybridge3_003511 CSc1c(C#N)c(nn1C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P14 compound treatment 0.332 0.0206 1.66 0.324 0.0187 1.7 2.3743 0.9999 2076966 Maybridge3_003512 Cc1cc(C)c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)nc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P15 compound treatment 0.325 0.0136 1.09 0.322 0.0168 1.52 1.8474 0.9868 1323409 Maybridge3_003513 Cc1cc(O)nc2n(C)nc(c3cccs3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P16 compound treatment 0.322 0.0106 0.85 0.318 0.0127 1.16 1.4198 0.9885 1628492 Maybridge3_003514 Cc1cc2ncc(c(C)n2n1)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P17 compound treatment 0.319 0.00756 0.61 0.317 0.0118 1.07 1.1848 0.9647 2076967 Maybridge3_003515 CSc1noc(c1C#N)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P18 compound treatment 0.325 0.0136 1.09 0.321 0.0158 1.43 1.7832 0.9912 2076968 Maybridge3_003516 CSc1c(C#N)c(N)nn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P19 compound treatment 0.323 0.0116 0.93 0.318 0.0127 1.16 1.4767 0.9942 2076969 Maybridge3_003517 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(Cl)cc1)/NCc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P20 compound treatment 0.324 0.0126 1.01 0.321 0.0158 1.43 1.7262 0.9857 2076970 Maybridge3_003518 CC(C)(C)S(=O)(=O)/C(=C/c1ccsc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P21 compound treatment 0.328 0.0166 1.33 0.324 0.0187 1.7 2.1466 0.9927 2076971 Maybridge3_003519 Cc1cc(NS(=O)(=O)c2ccc(Cl)s2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P22 compound treatment 0.329 0.0176 1.41 0.33 0.0248 2.25 2.5886 0.9751 2076972 Maybridge3_003520 CSc1nn2c(c(C#N)c(SC)nc2c1C#N)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P23 mock treatment 0.312 5.63E-4 0.05 0.308 0.00275 0.25 0.2085 0.822 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1440 P24 positive control 0.095 -0.216 -17.43 0.09 -0.215 -19.54 -26.14 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A01 compound treatment 0.316 -0.00338 -0.27 0.316 -0.00569 -0.52 -0.5572 -0.9551 1233192 Maybridge3_003521 Cc1nccc(n1)c2cccc(NC(=O)c3ccccc3Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A02 compound treatment 0.309 -0.0104 -0.84 0.326 0.00431 0.39 -0.314 -0.3403 1166051 Maybridge3_003522 CCOC(=O)CS(=O)c1sc(C(=O)OCC)c2CCCC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A03 compound treatment 0.31 -0.00938 -0.75 0.312 -0.00969 -0.88 -1.1556 -0.9971 2076973 Maybridge3_003523 Cc1nccc(n1)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A04 compound treatment 0.309 -0.0104 -0.84 0.312 -0.00969 -0.88 -1.2126 -0.9997 2076974 Maybridge3_003524 CSc1sc(c2ccn(n2)C(=O)C)c3CC(C)(C)CC(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A05 compound treatment 0.304 -0.0154 -1.24 0.31 -0.0117 -1.06 -1.6256 -0.997 2076975 Maybridge3_003525 O=S(=O)(CCS(=O)(=O)c1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A06 compound treatment 0.305 -0.0144 -1.16 0.31 -0.0117 -1.06 -1.5687 -0.9991 2076976 Maybridge3_003526 CCOC(=O)c1sc(SC)c(C(C)O)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A07 compound treatment 0.336 0.0166 1.34 0.319 -0.00269 -0.24 0.7741 0.5689 1188675 Maybridge3_003527 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A08 compound treatment 0.309 -0.0104 -0.84 0.31 -0.0117 -1.06 -1.3409 -0.993 2076977 Maybridge3_003528 CSc1sc(C(=O)N)c(C)c1C=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A09 compound treatment 0.301 -0.0184 -1.48 0.31 -0.0117 -1.06 -1.7965 -0.9867 2076978 Maybridge3_003529 CCCS(=O)(=O)c1cnc(SC)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A10 compound treatment 0.301 -0.0184 -1.48 0.306 -0.0157 -1.42 -2.0532 -0.9998 2076979 Maybridge3_003530 Clc1ccc(cc1)S(=O)(=O)CCNCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A11 compound treatment 0.324 0.00462 0.37 0.329 0.00731 0.66 0.7327 0.9627 2076980 Maybridge3_003531 Cc1nc(cs1)c2ccc(s2)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A12 compound treatment 0.311 -0.00838 -0.67 0.318 -0.00369 -0.33 -0.7136 -0.9477 2076981 Maybridge3_003532 Cn1nc(cc1C(F)(F)F)c2ccc(s2)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A13 compound treatment 0.311 -0.00838 -0.67 0.321 -6.88E-4 -0.06 -0.521 -0.7693 1126341 Maybridge3_003533 COC(=O)c1cnc2n(C)nc(C)c2c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A14 compound treatment 0.306 -0.0134 -1.08 0.315 -0.00669 -0.61 -1.1908 -0.9632 2076982 Maybridge3_003534 COC(=O)C1=C(CSC1)Nc2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A15 compound treatment 0.313 -0.00638 -0.51 0.318 -0.00369 -0.33 -0.5997 -0.9785 1224748 Maybridge3_003535 COC(=O)c1sc(N2CCCC2)c(c1N)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A16 compound treatment 0.215 -0.104 -8.4 0.229 -0.0927 -8.41 -11.8924 -1.0 3178044 Maybridge3_003536 SC(=S)N1CCCCC1.C1CCNCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A17 compound treatment 0.316 -0.00338 -0.27 0.318 -0.00369 -0.33 -0.4289 -0.9947 2076983 Maybridge3_003537 Cn1nc(c(C#N)c1S(=O)(=O)C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A18 compound treatment 0.305 -0.0144 -1.16 0.315 -0.00669 -0.61 -1.2478 -0.9546 2076984 Maybridge3_003538 CC1(C)CC(=O)C=C(SCC(=O)Nc2ccc(Cl)cc2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A19 compound treatment 0.307 -0.0124 -1.0 0.313 -0.00869 -0.79 -1.2623 -0.9933 1454332 Maybridge3_003539 Clc1ccc(cc1)c2nc(CS(=O)(=O)Cc3ccco3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A20 compound treatment 0.355 0.0356 2.87 0.35 0.0283 2.57 3.8458 0.9985 2076985 Maybridge3_003540 CSc1noc(c1C#N)c2ccc(s2)S(=O)(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A21 compound treatment 0.307 -0.0124 -1.0 0.315 -0.00669 -0.61 -1.1339 -0.9717 2076986 Maybridge3_003541 CC(C)Sc1sc(C#N)c2CC(C)(C)CC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A22 compound treatment 0.309 -0.0104 -0.84 0.317 -0.00469 -0.43 -0.8916 -0.951 2076987 Maybridge3_003542 c1csc(c1)c2nnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A23 mock treatment 0.304 -0.0154 -1.24 0.308 -0.0137 -1.24 -1.754 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 A24 positive control 0.081 -0.238 -19.2 0.082 -0.24 -21.76 -28.9576 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B01 compound treatment 0.35 0.0306 2.47 0.358 0.0363 3.3 4.0745 0.9898 2076988 Maybridge3_003543 CN1c2ccsc2C(=O)/C(=C\Nc3ccncc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B02 compound treatment 0.329 0.00962 0.78 0.338 0.0163 1.48 1.5951 0.9544 2076989 Maybridge3_003544 CCOC(=O)c1sc(C#N)c2C(=O)CC(C)(C)Cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B03 compound treatment 0.326 0.00662 0.53 0.334 0.0123 1.12 1.1675 0.9427 2076990 Maybridge3_003545 FC(F)(F)c1cc(NS(=O)(=O)c2ccccn2)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B04 compound treatment 0.332 0.0126 1.02 0.33 0.00831 0.75 1.2524 0.9892 2076991 Maybridge3_003546 Cc1ccc(cc1)S(=O)(=NC(=O)CSc2ccc(cn2)C(F)(F)F)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B05 compound treatment 0.348 0.0286 2.31 0.334 0.0123 1.12 2.4202 0.9448 2076992 Maybridge3_003547 Cc1csc2sc(c(C)c12)c3ccnc(SCC(=O)NCC=C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B06 compound treatment 0.323 0.00362 0.29 0.329 0.00731 0.66 0.6758 0.9319 2076993 Maybridge3_003548 CS(=O)(=O)C(=C1SCCCCS1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B07 compound treatment 0.326 0.00662 0.53 0.336 0.0143 1.3 1.2959 0.9227 2076994 Maybridge3_003549 CS(=O)(=NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B08 compound treatment 0.324 0.00462 0.37 0.331 0.00931 0.85 0.8611 0.9322 2076995 Maybridge3_003550 FC(F)(F)c1ccnc(c1)S(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B09 compound treatment 0.464 0.145 11.65 0.433 0.111 10.1 15.3797 0.9975 2076996 Maybridge3_003551 CN(C)n1cccc1/C=N/C(=C(\N)/C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B10 compound treatment 0.33 0.0106 0.86 0.348 0.0263 2.39 2.2939 0.9041 2076997 Maybridge3_003552 Fc1ccc(NC(=O)c2nccnc2Oc3cccc(c3)C(F)(F)F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B11 compound treatment 0.321 0.00162 0.13 0.332 0.0103 0.94 0.7544 0.7982 2076998 Maybridge3_003553 FC(F)(F)c1ccc(nc1)S(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B12 compound treatment 0.323 0.00362 0.29 0.328 0.00631 0.57 0.6116 0.951 2076999 Maybridge3_003554 Cc1c(N)scc1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B13 compound treatment 0.322 0.00262 0.21 0.324 0.00231 0.21 0.2979 1.0 1357350 Maybridge3_003555 O=S(=O)(N1CCCC1)c2ccc(s2)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B14 compound treatment 0.33 0.0106 0.86 0.33 0.00831 0.75 1.1385 0.998 2077000 Maybridge3_003556 CS(=O)(=O)/C(=C/N=S(=O)(C)c1ccsc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B15 compound treatment 0.328 0.00862 0.69 0.339 0.0173 1.57 1.6023 0.9326 2077001 Maybridge3_003557 Cn1c(CSc2cccs2)nnc1SCC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B16 compound treatment 0.311 -0.00838 -0.67 0.322 3.12E-4 0.03 -0.4568 -0.6768 2077002 Maybridge3_003558 CS(=O)(=O)/C(=C/c1ccccc1OCc2c(Cl)cccc2Cl)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B17 compound treatment 0.332 0.0126 1.02 0.334 0.0123 1.12 1.5092 0.9989 2077003 Maybridge3_003559 Cn1c(SCCS(=O)(=O)c2ccc(OC(F)(F)F)cc2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B18 compound treatment 0.339 0.0196 1.58 0.346 0.0243 2.21 2.678 0.9866 2077004 Maybridge3_003560 Clc1ccc(NC(=O)c2cccnc2SCCS(=O)(=O)c3ccccc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B19 compound treatment 0.328 0.00862 0.69 0.337 0.0153 1.39 1.4739 0.9486 2077005 Maybridge3_003561 COC(=O)c1sc(SC)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B20 compound treatment 0.333 0.0136 1.1 0.345 0.0233 2.12 2.2721 0.9532 1676929 Maybridge3_003562 CN(C)C(=O)c1cccnc1SCCS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B21 compound treatment 0.338 0.0186 1.5 0.352 0.0303 2.75 3.0061 0.9593 2077006 Maybridge3_003563 COC(=O)C1=C(CSC1)Nc2cccc(c2)c3nn(C)cc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B22 compound treatment 0.331 0.0116 0.94 0.334 0.0123 1.12 1.4522 0.9961 2077007 Maybridge3_003564 FC(F)(F)c1ccc(nc1)S(=O)(=O)Cc2ccc(o2)C(=O)Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B23 mock treatment 0.32 6.25E-4 0.05 0.326 0.00431 0.39 0.3124 0.7915 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 B24 positive control 0.081 -0.238 -19.2 0.082 -0.24 -21.76 -28.9576 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C01 compound treatment 0.317 -0.00238 -0.19 0.328 0.00631 0.57 0.2699 0.4469 2077008 Maybridge3_003565 Cc1ccc(CS(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C02 compound treatment 0.274 -0.0454 -3.65 0.291 -0.0307 -2.79 -4.5534 -0.991 2077009 Maybridge3_003566 CS(=O)c1sc(C#N)c2CCCC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C03 compound treatment 0.324 0.00462 0.37 0.324 0.00231 0.21 0.4118 0.9632 2077010 Maybridge3_003567 Cc1cc(n2nc(cc2n1)c3cccs3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C04 compound treatment 0.316 -0.00338 -0.27 0.326 0.00431 0.39 0.0846 0.1776 2077011 Maybridge3_003568 CCOC(=O)c1sc2sc(C(=O)OCC)c(c3ccco3)c2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C05 compound treatment 0.317 -0.00238 -0.19 0.323 0.00131 0.12 -0.051 -0.2263 2077012 Maybridge3_003569 Cc1cc2nc(cc(C)n2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C06 compound treatment 0.321 0.00162 0.13 0.322 3.12E-4 0.03 0.1126 0.8409 1689057 Maybridge3_003570 CSc1sc(C(=O)Oc2ccccc2)c3CC(C)(C)CC(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C07 compound treatment 0.321 0.00162 0.13 0.325 0.00331 0.3 0.3051 0.9305 2077013 Maybridge3_003571 CCS(=O)c1scc(c1C#N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C08 compound treatment 0.322 0.00262 0.21 0.337 0.0153 1.39 1.1323 0.8054 2077014 Maybridge3_003572 Clc1ccc(NC=C2C(=O)CC(CC2=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C09 compound treatment 0.325 0.00562 0.45 0.328 0.00631 0.57 0.7255 0.9932 2077015 Maybridge3_003573 CC(C)(C)S(=O)(=O)/C(=C/NN1CCCCC1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C10 compound treatment 0.324 0.00462 0.37 0.322 3.12E-4 0.03 0.2834 0.7588 1642259 Maybridge3_003574 CS(=O)(=O)c1sc(C(=O)Nc2ccc(Cl)cc2)c3CCC=Cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C11 compound treatment 0.326 0.00662 0.53 0.329 0.00731 0.66 0.8466 0.9941 2077016 Maybridge3_003575 Cc1cccc(c1)c2ncc(c(N)n2)S(=O)(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C12 compound treatment 0.324 0.00462 0.37 0.343 0.0213 1.93 1.6313 0.828 1551038 Maybridge3_003576 CC(=O)N(CCS(=O)(=O)c1ccc(Cl)cc1)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C13 compound treatment 0.359 0.0396 3.19 0.369 0.0473 4.29 5.293 0.9893 1332321 Maybridge3_003577 COc1c(cnc2n(C)nc(C)c12)C(=O)Nc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C14 compound treatment 0.327 0.00762 0.61 0.331 0.00931 0.85 1.0319 0.9877 2077017 Maybridge3_003578 CCCCS(=O)c1sc(C(=O)OCC)c2CCCC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C15 compound treatment 0.331 0.0116 0.94 0.336 0.0143 1.3 1.5806 0.9871 1547710 Maybridge3_003579 CSc1c2C(=O)CC(C)(C)Cc2nc3cc(nn13)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C16 compound treatment 0.326 0.00662 0.53 0.334 0.0123 1.12 1.1675 0.9427 2077018 Maybridge3_003580 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C17 compound treatment 0.321 0.00162 0.13 0.327 0.00531 0.48 0.4335 0.8676 2077019 Maybridge3_003581 Fc1cccc(Cl)c1/C=C(\C#N)/S(=O)(=O)Cc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C18 compound treatment 0.333 0.0136 1.1 0.337 0.0153 1.39 1.7587 0.9931 2077020 Maybridge3_003582 CC1(C)CC(=O)C=C(SCc2cccc(Cl)c2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C19 compound treatment 0.315 -0.00438 -0.35 0.318 -0.00369 -0.33 -0.4858 -0.9997 2077021 Maybridge3_003583 COC(=O)c1cscc1OC(=O)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C20 compound treatment 0.33 0.0106 0.86 0.34 0.0183 1.66 1.7804 0.9523 1547021 Maybridge3_003584 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)NCC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C21 compound treatment 0.32 6.25E-4 0.05 0.329 0.00731 0.66 0.5049 0.7585 2077022 Maybridge3_003585 COC(=O)c1sccc1N(C)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C22 compound treatment 0.341 0.0216 1.74 0.345 0.0233 2.12 2.7277 0.9953 1269871 Maybridge3_003586 CSc1sc(C(=O)N2CCOCC2)c-3c1S(=O)(=O)N(C)c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C23 mock treatment 0.314 -0.00538 -0.43 0.316 -0.00569 -0.52 -0.6711 -0.9962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 C24 positive control 0.084 -0.235 -18.95 0.082 -0.24 -21.76 -28.7868 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D01 compound treatment 0.328 0.00862 0.69 0.337 0.0153 1.39 1.4739 0.9486 1701111 Maybridge3_003587 Cc1noc(C)c1S(=O)(=O)N=S(=O)(C)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D02 compound treatment 0.322 0.00262 0.21 0.333 0.0113 1.03 0.8756 0.8352 2077023 Maybridge3_003588 COC(=O)c1sccc1N/C=C/2\C(=O)CCC(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D03 compound treatment 0.32 6.25E-4 0.05 0.332 0.0103 0.94 0.6975 0.7441 2077024 Maybridge3_003589 FC(F)(F)c1ccc(Sc2cccs2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D04 compound treatment 0.321 0.00162 0.13 0.327 0.00531 0.48 0.4335 0.8676 2077025 Maybridge3_003590 Cc1ccc(cc1)S(=O)(=NC(=O)CSc2ccc(Cl)cc2)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D05 compound treatment 0.324 0.00462 0.37 0.335 0.0133 1.21 1.1178 0.884 2077026 Maybridge3_003591 CCOC(=O)CSc1nccc(n1)c2sc3scc(C)c3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D06 compound treatment 0.319 -3.75E-4 -0.03 0.328 0.00631 0.57 0.3838 0.6689 2077027 Maybridge3_003592 O=S(=O)(C(=C1SCCCCS1)C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D07 compound treatment 0.382 0.0626 5.04 0.38 0.0583 5.29 7.3087 0.9997 2077028 Maybridge3_003593 CN(C)n1cccc1/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D08 compound treatment 0.443 0.124 9.96 0.448 0.126 11.47 15.1467 0.9975 2077029 Maybridge3_003594 Cn1nc(cc1C(F)(F)F)c2ccc(/C=N/C(=C(\N)/C#N)/C#N)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D09 compound treatment 0.32 6.25E-4 0.05 0.331 0.00931 0.85 0.6333 0.7479 2077030 Maybridge3_003595 Cn1c(CSc2cccs2)nnc1SCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D10 compound treatment 0.321 0.00162 0.13 0.338 0.0163 1.48 1.1395 0.7666 2077031 Maybridge3_003596 O/N=C\1/CCCCC1CCS(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D11 compound treatment 0.335 0.0156 1.26 0.343 0.0213 1.93 2.2576 0.9783 2077032 Maybridge3_003597 Cc1csc2sc(/C=N/C(=C(\N)/C#N)/C#N)c(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D12 compound treatment 0.341 0.0216 1.74 0.351 0.0293 2.66 3.1128 0.9789 2077033 Maybridge3_003598 CSc1sc(c(c1C#N)c2ccccc2)c3ccnc(SCC(=O)N)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D13 compound treatment 0.346 0.0266 2.14 0.351 0.0293 2.66 3.3975 0.9943 2077034 Maybridge3_003599 COC(=O)c1sccc1NC(=O)c2cc(c(SC)s2)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D14 compound treatment 0.327 0.00762 0.61 0.335 0.0133 1.21 1.2886 0.9507 2077035 Maybridge3_003600 CS(=O)(=N/C=C(\C#N)/S(=O)(=O)c1ccc(cn1)C(F)(F)F)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D15 compound treatment 0.319 -3.75E-4 -0.03 0.335 0.0133 1.21 0.8331 0.6892 1408473 Maybridge3_003601 OC(=O)C1=C(CSC1)Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D16 compound treatment 0.344 0.0246 1.98 0.344 0.0223 2.03 2.8343 0.9999 2077036 Maybridge3_003602 Cn1c(CSCc2nc(cs2)c3ccc(Cl)cc3)nnc1SCC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D17 compound treatment 0.357 0.0376 3.03 0.366 0.0443 4.02 4.9866 0.9902 2077037 Maybridge3_003603 CSc1sc(c(C)c1c2ccn(n2)S(=O)(=O)C)c3nc(C)cs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D18 compound treatment 0.329 0.00962 0.78 0.339 0.0173 1.57 1.6593 0.9469 2077038 Maybridge3_003604 OC(=O)c1cccnc1SCCS(=O)(=O)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D19 compound treatment 0.318 -0.00138 -0.11 0.325 0.00331 0.3 0.1343 0.4192 2077039 Maybridge3_003605 CN1c2ccsc2C(=O)/C(=C\N=S(=O)(C)c3ccc(C)cc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D20 compound treatment 0.344 0.0246 1.98 0.346 0.0243 2.21 2.9627 0.9986 2077040 Maybridge3_003606 Cc1onc(c1C(=O)/N=S/2\CCC3(C2)OCCO3)c4c(Cl)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D21 compound treatment 0.324 0.00462 0.37 0.339 0.0173 1.57 1.3746 0.8511 1486392 Maybridge3_003607 COC(=O)C1=C(CSC1)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D22 compound treatment 0.335 0.0156 1.26 0.34 0.0183 1.66 2.0651 0.9906 3178069 Maybridge3_003608 Cc1cc(C)c(c(C)c1)S(=O)(=O)O.CS(=N)(=O)c1ccc(OC(=O)c2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D23 mock treatment 0.317 -0.00238 -0.19 0.324 0.00231 0.21 0.0132 0.0465 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 D24 positive control 0.084 -0.235 -18.95 0.085 -0.237 -21.48 -28.5943 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E01 compound treatment 0.323 0.00362 0.29 0.333 0.0113 1.03 0.9325 0.8735 2077041 Maybridge3_003609 Clc1ccc(CS(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E02 compound treatment 0.324 0.00462 0.37 0.341 0.0193 1.75 1.5029 0.8386 2077042 Maybridge3_003610 CCOC(=O)CSc1sc(C(=O)OCC)c2CCCC(O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E03 compound treatment 0.321 0.00162 0.13 0.33 0.00831 0.75 0.6261 0.8175 2077043 Maybridge3_003611 O/N=C/1\C(Cn2ccnc2)CCc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E04 compound treatment 0.298 -0.0214 -1.72 0.317 -0.00469 -0.43 -1.518 -0.8561 2077044 Maybridge3_003612 CCOC(=O)CSc1sc(C(=O)OCC)c(c1C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E05 compound treatment 0.305 -0.0144 -1.16 0.314 -0.00769 -0.7 -1.3119 -0.9706 2077045 Maybridge3_003613 Brc1csc(c1)C2SCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E06 compound treatment 0.342 0.0226 1.82 0.349 0.0273 2.48 3.0413 0.9885 2077046 Maybridge3_003614 COC(=O)c1cc(C(=O)N)c(SC)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E07 compound treatment 0.32 6.25E-4 0.05 0.334 0.0123 1.12 0.8259 0.7382 2077047 Maybridge3_003615 Cc1nc(no1)c2cnn3c(C)cc(nc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E08 compound treatment 0.332 0.0126 1.02 0.336 0.0143 1.3 1.6375 0.9926 2077048 Maybridge3_003616 Clc1ccccc1NC=C2C(=O)CC(CC2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E09 compound treatment 0.334 0.0146 1.18 0.342 0.0203 1.84 2.1365 0.9766 2077049 Maybridge3_003617 FC(F)(F)c1cc(cc(c1)S(=O)(=O)/C(=C/NN2CCOCC2)/C#N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E10 compound treatment 0.315 -0.00438 -0.35 0.324 0.00231 0.21 -0.1007 -0.2455 2077050 Maybridge3_003618 Cc1csc2sc(c(C)c12)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E11 compound treatment 0.329 0.00962 0.78 0.336 0.0143 1.3 1.4667 0.9695 2077051 Maybridge3_003619 CS(=O)c1scc(c1C#N)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E12 compound treatment 0.329 0.00962 0.78 0.328 0.00631 0.57 0.9532 0.989 2077052 Maybridge3_003620 Nc1ncc(c(N)n1)S(=O)(=O)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E13 compound treatment 0.338 0.0186 1.5 0.338 0.0163 1.48 2.1075 1.0 1197298 Maybridge3_003621 COC(=O)c1sc(N2CCOCC2)c(C#N)c1c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E14 compound treatment 0.347 0.0276 2.22 0.351 0.0293 2.66 3.4544 0.996 2077053 Maybridge3_003622 Cn1nc(cc1C(F)(F)F)c2ccc(s2)c3ccn(n3)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E15 compound treatment 0.335 0.0156 1.26 0.343 0.0213 1.93 2.2576 0.9783 1119142 Maybridge3_003623 COC(=O)c1sc(N2CCCC2)c(C#N)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E16 compound treatment 0.318 -0.00138 -0.11 0.328 0.00631 0.57 0.3269 0.5601 2077054 Maybridge3_003624 C/C(=N\O)/c1sc2scc(C)c2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E17 compound treatment 0.324 0.00462 0.37 0.332 0.0103 0.94 0.9253 0.9184 2077055 Maybridge3_003625 Clc1ccc(/C=C(\C#N)/S(=O)(=O)Cc2ccco2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E18 compound treatment 0.327 0.00762 0.61 0.333 0.0113 1.03 1.1603 0.9698 2077056 Maybridge3_003626 CC1(C)CC(=O)C=C(SCC(=O)Nc2ccccc2Cl)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E19 compound treatment 0.253 -0.0664 -5.34 0.293 -0.0287 -2.6 -5.6208 -0.9454 1653018 Maybridge3_003627 O=S(=O)(Cc1ccco1)Cc2nc(cs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E20 compound treatment 0.331 0.0116 0.94 0.337 0.0153 1.39 1.6448 0.9815 1132451 Maybridge3_003628 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E21 compound treatment 0.315 -0.00438 -0.35 0.324 0.00231 0.21 -0.1007 -0.2455 1577227 Maybridge3_003629 CCOC(=O)c1sc(SC)c(c1N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E22 compound treatment 0.338 0.0186 1.5 0.337 0.0153 1.39 2.0434 0.9993 1580137 Maybridge3_003630 CSc1sc(C(=O)N(C)C)c-2c1S(=O)(=O)N(C)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E23 mock treatment 0.315 -0.00438 -0.35 0.318 -0.00369 -0.33 -0.4858 -0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 E24 positive control 0.086 -0.233 -18.79 0.086 -0.236 -21.39 -28.4162 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F01 compound treatment 0.326 0.00662 0.53 0.335 0.0133 1.21 1.2317 0.9325 1117689 Maybridge3_003631 CN(CCS(=O)(=O)c1ccc(Cl)cc1)Cc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F02 compound treatment 0.326 0.00662 0.53 0.334 0.0123 1.12 1.1675 0.9427 2077057 Maybridge3_003632 CCOC(=O)c1c(C)c(C)sc1N/C=C/2\C(=O)CCC(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F03 compound treatment 0.326 0.00662 0.53 0.328 0.00631 0.57 0.7824 0.9994 2077058 Maybridge3_003633 Cc1nn(C)c2nc(cc(C)c12)n3nc(cc3N)c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F04 compound treatment 0.326 0.00662 0.53 0.34 0.0183 1.66 1.5526 0.8894 2077059 Maybridge3_003634 CC1(C)CC(=O)c2c(SCCO)sc(C#N)c2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F05 compound treatment 0.339 0.0196 1.58 0.338 0.0163 1.48 2.1645 0.9995 2077060 Maybridge3_003635 CN1c2sc(C)c(C)c2C(=O)/C(=C\Nc3cccnc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F06 compound treatment 0.315 -0.00438 -0.35 0.33 0.00831 0.75 0.2844 0.3416 2077061 Maybridge3_003636 Brc1ccc(s1)c2nc3ccccc3[nH]c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F07 compound treatment 0.324 0.00462 0.37 0.33 0.00831 0.75 0.7969 0.947 1548838 Maybridge3_003637 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)c3ccccc3Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F08 compound treatment 0.331 0.0116 0.94 0.34 0.0183 1.66 1.8373 0.9631 1688595 Maybridge3_003638 Cc1nn(C)c2ncc(C(=O)N)c(Oc3ccc(Cl)cc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F09 compound treatment 0.321 0.00162 0.13 0.337 0.0153 1.39 1.0754 0.7703 2077062 Maybridge3_003639 FC(F)(F)Oc1ccc(SCC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F10 compound treatment 0.331 0.0116 0.94 0.328 0.00631 0.57 1.0671 0.9722 2077063 Maybridge3_003640 Cc1ccc(cc1)S(=O)(=O)N=S(=O)(C)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F11 compound treatment 0.325 0.00562 0.45 0.336 0.0143 1.3 1.2389 0.9005 2077064 Maybridge3_003641 Cc1nn(Cc2nnc(SCC(=O)c3ccc(Cl)cc3)o2)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F12 compound treatment 0.334 0.0146 1.18 0.334 0.0123 1.12 1.623 0.9997 1520307 Maybridge3_003642 Cn1ccnc1SCCS(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F13 compound treatment 0.323 0.00362 0.29 0.339 0.0173 1.57 1.3176 0.8244 2077065 Maybridge3_003643 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2cc(c(SC)s2)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F14 compound treatment 0.276 -0.0434 -3.49 0.291 -0.0307 -2.79 -4.4395 -0.9937 2077066 Maybridge3_003644 Clc1ccccc1SCc2cccc(c2)C(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F15 compound treatment 0.333 0.0136 1.1 0.341 0.0193 1.75 2.0154 0.9745 2077067 Maybridge3_003645 CS(=O)(=O)c1cc2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F16 compound treatment 0.337 0.0176 1.42 0.34 0.0183 1.66 2.179 0.9969 2077068 Maybridge3_003646 CCOC(=O)CSc1c(C)[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F17 compound treatment 0.336 0.0166 1.34 0.342 0.0203 1.84 2.2504 0.9876 2077069 Maybridge3_003647 CSc1sc(Cl)c2CCCC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F18 compound treatment 0.331 0.0116 0.94 0.344 0.0223 2.03 2.0941 0.9385 1445303 Maybridge3_003648 Nc1cc(Cl)ccc1C(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F19 compound treatment 0.333 0.0136 1.1 0.334 0.0123 1.12 1.5661 1.0 2077070 Maybridge3_003649 Clc1ccccc1NC=C2C(=O)CC(CC2=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F20 compound treatment 0.337 0.0176 1.42 0.341 0.0193 1.75 2.2432 0.9945 1657541 Maybridge3_003650 COC(=O)c1cnc(S(=O)CC#N)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F21 compound treatment 0.33 0.0106 0.86 0.343 0.0213 1.93 1.9729 0.9327 2077071 Maybridge3_003651 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2ccc3OCCOc3c2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F22 compound treatment 0.328 0.00862 0.69 0.338 0.0163 1.48 1.5381 0.9405 1734009 Maybridge3_003652 OC(=O)C1SCCN1C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F23 mock treatment 0.32 6.25E-4 0.05 0.321 -6.88E-4 -0.06 -0.0085 -0.1065 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 F24 positive control 0.086 -0.233 -18.79 0.087 -0.235 -21.3 -28.352 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G01 compound treatment 0.331 0.0116 0.94 0.348 0.0263 2.39 2.3508 0.9164 2077072 Maybridge3_003653 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G02 compound treatment 0.305 -0.0144 -1.16 0.32 -0.00169 -0.15 -0.9268 -0.7938 2077073 Maybridge3_003654 CCOC(=O)c1sc(SC)c2C=CCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G03 compound treatment 0.314 -0.00538 -0.43 0.3 -0.0217 -1.97 -1.6981 -0.8425 2077074 Maybridge3_003655 Fc1cccc(Cl)c1CS(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G04 compound treatment 0.355 0.0356 2.87 0.354 0.0323 2.93 4.1025 0.9999 2077075 Maybridge3_003656 Nc1c(C#N)sc2sc(C#N)c(c3cccs3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G05 compound treatment 0.323 0.00362 0.29 0.332 0.0103 0.94 0.8683 0.8856 1582187 Maybridge3_003657 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G06 compound treatment 0.313 -0.00638 -0.51 0.319 -0.00269 -0.24 -0.5355 -0.9422 2077076 Maybridge3_003658 CCOC(=O)c1sc2sc(c(C)c2c1C)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G07 compound treatment 0.326 0.00662 0.53 0.331 0.00931 0.85 0.975 0.9754 2077077 Maybridge3_003659 Clc1cc(Cl)cc(OC(=O)c2ccc(s2)c3ccccn3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G08 compound treatment 0.309 -0.0104 -0.84 0.31 -0.0117 -1.06 -1.3409 -0.993 2077078 Maybridge3_003660 N/C(=C(/NCc1ccccc1Sc2ccc(Cl)cc2)\C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G09 compound treatment 0.326 0.00662 0.53 0.331 0.00931 0.85 0.975 0.9754 2077079 Maybridge3_003661 CC(C)S(=O)(=O)/C(=C/NN1CCOCC1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G10 compound treatment 0.32 6.25E-4 0.05 0.327 0.00531 0.48 0.3766 0.7767 1697342 Maybridge3_003662 CS(=O)(=O)c1sc(C(=O)Sc2ccccc2)c3CCC=Cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G11 compound treatment 0.323 0.00362 0.29 0.328 0.00631 0.57 0.6116 0.951 2077080 Maybridge3_003663 CSc1scc(Cl)c1S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G12 compound treatment 0.327 0.00762 0.61 0.331 0.00931 0.85 1.0319 0.9877 2077081 Maybridge3_003664 CSc1ncc(c(N)n1)S(=O)(=O)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G13 compound treatment 0.329 0.00962 0.78 0.335 0.0133 1.21 1.4025 0.977 2077082 Maybridge3_003665 COC(=O)c1sc(N(C)C)c(C#N)c1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G14 compound treatment 0.343 0.0236 1.9 0.352 0.0303 2.75 3.2908 0.9838 2077083 Maybridge3_003666 CC(=O)n1ccc(n1)c2ccc(s2)c3cc(n(C)n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G15 compound treatment 0.333 0.0136 1.1 0.326 0.00431 0.39 1.0526 0.9036 1667785 Maybridge3_003667 CSc1nc2cc(nn2c(N)c1S(=O)(=O)C(C)C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G16 compound treatment 0.327 0.00762 0.61 0.33 0.00831 0.75 0.9677 0.9948 2077084 Maybridge3_003668 CSC(=CC(=O)c1sc2scc(C)c2c1C)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G17 compound treatment 0.34 0.0206 1.66 0.341 0.0193 1.75 2.414 0.9996 2077085 Maybridge3_003669 Clc1cccc(N/C=C(\C#N)/S(=O)(=O)Cc2ccco2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G18 compound treatment 0.334 0.0146 1.18 0.345 0.0233 2.12 2.3291 0.9617 2077086 Maybridge3_003670 CC1(C)CC(=O)C=C(SCCS(=O)(=O)c2ccccc2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G19 compound treatment 0.323 0.00362 0.29 0.322 3.12E-4 0.03 0.2265 0.7722 1536000 Maybridge3_003671 CCOC(=O)c1csc(CS(=O)(=O)Cc2ccco2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G20 compound treatment 0.338 0.0186 1.5 0.342 0.0203 1.84 2.3643 0.9947 1263850 Maybridge3_003672 CSc1nnc(c2ccc(s2)S(=O)(=O)N3CCCCC3)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G21 compound treatment 0.336 0.0166 1.34 0.339 0.0173 1.57 2.0578 0.9968 2077087 Maybridge3_003673 COC(=O)c1cc(c(SC)s1)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G22 compound treatment 0.326 0.00662 0.53 0.333 0.0113 1.03 1.1033 0.9535 2077088 Maybridge3_003674 CSc1nccc(n1)c2ccc(s2)S(=O)(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G23 mock treatment 0.314 -0.00538 -0.43 0.324 0.00231 0.21 -0.1576 -0.3277 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 G24 positive control 0.087 -0.232 -18.71 0.088 -0.234 -21.21 -28.2309 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H01 compound treatment 0.325 0.00562 0.45 0.331 0.00931 0.85 0.918 0.9572 2077089 Maybridge3_003675 COc1ccc(cc1)c2ccnc(SC)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H02 compound treatment 0.324 0.00462 0.37 0.339 0.0173 1.57 1.3746 0.8511 2077090 Maybridge3_003676 O=C/1CCC(C(=O)\C1=C/Nc2cccnc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H03 compound treatment 0.327 0.00762 0.61 0.33 0.00831 0.75 0.9677 0.9948 2077091 Maybridge3_003677 CCOC(=O)c1c(C)c(C)sc1N(C)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H04 compound treatment 0.337 0.0176 1.42 0.338 0.0163 1.48 2.0506 0.9998 1405816 Maybridge3_003678 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)N2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H05 compound treatment 0.339 0.0196 1.58 0.348 0.0263 2.39 2.8063 0.9799 1378974 Maybridge3_003679 CC1C(=O)N(C)c2ccc(cc12)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H06 compound treatment 0.325 0.00562 0.45 0.334 0.0123 1.12 1.1106 0.9209 2077092 Maybridge3_003680 O=S(=O)(c1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H07 compound treatment 0.322 0.00262 0.21 0.334 0.0123 1.12 0.9397 0.8262 1278899 Maybridge3_003681 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)Nc3cccc(Cl)c3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H08 compound treatment 0.325 0.00562 0.45 0.333 0.0113 1.03 1.0464 0.9323 1408120 Maybridge3_003682 CCOC(=O)c1sc(c-2c1CCc3conc32)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H09 compound treatment 0.35 0.0306 2.47 0.354 0.0323 2.93 3.8178 0.9963 2077093 Maybridge3_003683 CC(C)(C)c1csc(n1)c2ccc(/C=N/C(=C(\N)/C#N)/C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H10 compound treatment 0.326 0.00662 0.53 0.343 0.0213 1.93 1.7452 0.8696 2077094 Maybridge3_003684 CS(=O)(=NS(=O)(=O)c1ccccc1Cl)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H11 compound treatment 0.345 0.0256 2.06 0.344 0.0223 2.03 2.8912 1.0 2077095 Maybridge3_003685 Cc1nn(Cc2nnc(SCC(=O)C(C)(C)C)o2)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H12 compound treatment 0.303 -0.0164 -1.32 0.321 -6.88E-4 -0.06 -0.9765 -0.7397 2077096 Maybridge3_003686 CCOC(=O)COc1ccccc1/C=C(/C#N)\S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H13 compound treatment 0.339 0.0196 1.58 0.335 0.0133 1.21 1.9719 0.9912 2077097 Maybridge3_003687 COC(=O)CSc1sc(C#N)c2CC(C)(C)CC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H14 compound treatment 0.329 0.00962 0.78 0.331 0.00931 0.85 1.1458 0.9991 1498986 Maybridge3_003688 COC(=O)C1SCCN1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H15 compound treatment 0.34 0.0206 1.66 0.336 0.0143 1.3 2.0931 0.9926 1290743 Maybridge3_003689 CC(=O)Oc1ccc(Cl)cc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H16 compound treatment 0.371 0.0516 4.16 0.37 0.0483 4.39 6.0405 0.9996 1713681 Maybridge3_003690 COc1ccc(cc1)C(=O)N=S2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H17 compound treatment 0.339 0.0196 1.58 0.339 0.0173 1.57 2.2287 1.0 1602917 Maybridge3_003691 Clc1ccc(cc1)c2nc(no2)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H18 compound treatment 0.357 0.0376 3.03 0.349 0.0273 2.48 3.8955 0.995 2077098 Maybridge3_003692 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCSc2ncccc2C(=O)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H19 compound treatment 0.339 0.0196 1.58 0.343 0.0213 1.93 2.4854 0.995 2077099 Maybridge3_003693 FC(F)(F)c1cccc(NC=C2C(=O)CC(CC2=O)c3cccs3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H20 compound treatment 0.322 0.00262 0.21 0.332 0.0103 0.94 0.8114 0.8455 2077100 Maybridge3_003694 CC(C)(C)SC(=O)c1cccnc1SCCS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H21 compound treatment 0.326 0.00662 0.53 0.332 0.0103 0.94 1.0391 0.9645 2077101 Maybridge3_003695 O=S(=O)(/C(=C/Nc1ccc2OCCOc2c1)/C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H22 compound treatment 0.193 -0.126 -10.18 0.196 -0.126 -11.41 -15.2632 -0.9984 1696878 Maybridge3_003696 O=S(=O)(c1cccs1)c2nccnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H23 mock treatment 0.32 6.25E-4 0.05 0.327 0.00531 0.48 0.3766 0.7767 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 H24 positive control 0.088 -0.231 -18.63 0.089 -0.233 -21.12 -28.1098 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I01 compound treatment 0.331 0.0116 0.94 0.334 0.0123 1.12 1.4522 0.9961 2077102 Maybridge3_003697 O=S(=O)(/C(=C/c1cccs1)/C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I02 compound treatment 0.331 0.0116 0.94 0.338 0.0163 1.48 1.709 0.9755 2077103 Maybridge3_003698 CS(=O)(=N/C=C(\C#N)/S(=O)(=O)c1ccccn1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I03 compound treatment 0.329 0.00962 0.78 0.341 0.0193 1.75 1.7876 0.9327 2077104 Maybridge3_003699 O=S(=O)(Cc1cccc(C#N)c1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I04 compound treatment 0.334 0.0146 1.18 0.342 0.0203 1.84 2.1365 0.9766 2077105 Maybridge3_003700 CCOC(=O)c1sc2sc(C(=O)OCC)c(c2c1N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I05 compound treatment 0.321 0.00162 0.13 0.332 0.0103 0.94 0.7544 0.7982 2077106 Maybridge3_003701 Fc1ccc(NC(=O)c2cccnc2Sc3cccs3)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I06 compound treatment 0.324 0.00462 0.37 0.339 0.0173 1.57 1.3746 0.8511 2077107 Maybridge3_003702 CC(=O)OCc1ccc(/C=C(\C#N)/S(=O)(=O)C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I07 compound treatment 0.322 0.00262 0.21 0.338 0.0163 1.48 1.1965 0.7999 2077108 Maybridge3_003703 COc1ccc(OC(=O)c2ccc(s2)c3ccccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I08 compound treatment 0.317 -0.00238 -0.19 0.346 0.0243 2.21 1.4253 0.6434 2077109 Maybridge3_003704 Cc1ncc(CNS(=O)(=O)c2ccccc2C(F)(F)F)c(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I09 compound treatment 0.33 0.0106 0.86 0.33 0.00831 0.75 1.1385 0.998 1210189 Maybridge3_003705 COC(=O)COc1c(sc2ccccc12)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I10 compound treatment 0.327 0.00762 0.61 0.336 0.0143 1.3 1.3528 0.9414 2077110 Maybridge3_003706 CS(=O)c1sc(Br)c2CC(C)(C)CC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I11 compound treatment 0.333 0.0136 1.1 0.327 0.00531 0.48 1.1168 0.9319 1413428 Maybridge3_003707 CCC(C)S(=O)(=O)c1scc(c1C#N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I12 compound treatment 0.325 0.00562 0.45 0.33 0.00831 0.75 0.8538 0.9702 2077111 Maybridge3_003708 Cc1ncc(c(N)n1)S(=O)(=O)Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I13 compound treatment 0.333 0.0136 1.1 0.328 0.00631 0.57 1.181 0.9541 1311184 Maybridge3_003709 COC(=O)c1sc(N2CCCC2)c(C#N)c1c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I14 compound treatment 0.335 0.0156 1.26 0.336 0.0143 1.3 1.8083 0.9999 2077112 Maybridge3_003710 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I15 compound treatment 0.331 0.0116 0.94 0.331 0.00931 0.85 1.2597 0.9987 2077113 Maybridge3_003711 CS(=O)(=NS(=O)(=O)c1ccc(Cl)s1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I16 compound treatment 0.324 0.00462 0.37 0.341 0.0193 1.75 1.5029 0.8386 1518241 Maybridge3_003712 Clc1ccc(cc1)C(=O)NCc2ccc(s2)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I17 compound treatment 0.357 0.0376 3.03 0.339 0.0173 1.57 3.2536 0.9533 2077114 Maybridge3_003713 COC(=O)c1ccc(s1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I18 compound treatment 0.336 0.0166 1.34 0.336 0.0143 1.3 1.8653 0.9999 2077115 Maybridge3_003714 FC(F)(F)c1ccc(SCCS(=O)(=O)c2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I19 compound treatment 0.334 0.0146 1.18 0.349 0.0273 2.48 2.5858 0.9421 2077116 Maybridge3_003715 Cc1onc(c1C(=O)N=S(=O)(C)C)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I20 compound treatment 0.339 0.0196 1.58 0.341 0.0193 1.75 2.357 0.9987 2077117 Maybridge3_003716 CS(=O)(=NS(=O)(=O)c1ccc(s1)c2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I21 compound treatment 0.339 0.0196 1.58 0.34 0.0183 1.66 2.2929 0.9997 1013628 Maybridge3_003717 OC(=O)c1ccc(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I22 compound treatment 0.339 0.0196 1.58 0.343 0.0213 1.93 2.4854 0.995 2077118 Maybridge3_003718 CN1c2ccsc2C(=O)/C(=C\Nc3cccc(c3)C(F)(F)F)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I23 mock treatment 0.325 0.00562 0.45 0.325 0.00331 0.3 0.5329 0.9802 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 I24 positive control 0.089 -0.23 -18.55 0.088 -0.234 -21.21 -28.117 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J01 compound treatment 0.33 0.0106 0.86 0.338 0.0163 1.48 1.652 0.966 2077119 Maybridge3_003719 Cc1nn(CCS(=O)(=O)c2ccc(Cl)cc2)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J02 compound treatment 0.333 0.0136 1.1 0.339 0.0173 1.57 1.887 0.9846 2077120 Maybridge3_003720 Cn1c(SCC(=O)N=S(=O)(C)c2ccc(Cl)cc2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J03 compound treatment 0.321 0.00162 0.13 0.328 0.00631 0.57 0.4977 0.8468 2077121 Maybridge3_003721 Clc1ccc(NC(=O)CSC2=CC(=O)CC(S2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J04 compound treatment 0.326 0.00662 0.53 0.336 0.0143 1.3 1.2959 0.9227 2077122 Maybridge3_003722 Clc1ccc(cc1)S(=O)(=O)/C(=C/N2CCc3ccccc23)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J05 compound treatment 0.325 0.00562 0.45 0.331 0.00931 0.85 0.918 0.9572 1149313 Maybridge3_003723 CCOC(=O)c1csc(n1)c2sc(SC)c3C(=O)CCCc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J06 compound treatment 0.323 0.00362 0.29 0.345 0.0233 2.12 1.7027 0.7971 2077123 Maybridge3_003724 Clc1ccc(cc1)S(=N)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J07 compound treatment 0.324 0.00462 0.37 0.334 0.0123 1.12 1.0536 0.8944 1117842 Maybridge3_003725 CNC(=O)Oc1ccc(NC2=C(CSC2)C(=O)OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J08 compound treatment 0.329 0.00962 0.78 0.329 0.00731 0.66 1.0174 0.997 1010895 Maybridge3_003726 COC(=O)c1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J09 compound treatment 0.33 0.0106 0.86 0.335 0.0133 1.21 1.4595 0.9857 2077124 Maybridge3_003727 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J10 compound treatment 0.323 0.00362 0.29 0.329 0.00731 0.66 0.6758 0.9319 2077125 Maybridge3_003728 C/S(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J11 compound treatment 0.336 0.0166 1.34 0.335 0.0133 1.21 1.8011 0.9987 1411162 Maybridge3_003729 CC(C)c1ccc(NC(=O)CSc2ncc3C(=O)CC(C)(C)Cc3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J12 compound treatment 0.316 -0.00338 -0.27 0.322 3.12E-4 0.03 -0.1721 -0.6299 2077126 Maybridge3_003730 CCOC(=O)COc1ccccc1/C=C(/C#N)\S(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J13 compound treatment 0.333 0.0136 1.1 0.325 0.00331 0.3 0.9884 0.8689 1434422 Maybridge3_003731 CCCS(=O)(=O)c1cc2cc(Cl)ccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J14 compound treatment 0.311 -0.00838 -0.67 0.32 -0.00169 -0.15 -0.5852 -0.8462 2077127 Maybridge3_003732 CS(=O)(=O)/C(=C/c1ccsc1Sc2ccc(Cl)cc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J15 compound treatment 0.332 0.0126 1.02 0.333 0.0113 1.03 1.445 1.0 2077128 Maybridge3_003733 OC(=O)c1cscc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J16 compound treatment 0.344 0.0246 1.98 0.342 0.0203 1.84 2.7059 0.9993 1241376 Maybridge3_003734 COc1ccccc1C(=O)N=S2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J17 compound treatment 0.338 0.0186 1.5 0.327 0.00531 0.48 1.4015 0.8896 2077129 Maybridge3_003735 CSc1nc(nc(c1C#N)c2ccccc2Cl)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J18 compound treatment 0.326 0.00662 0.53 0.317 -0.00469 -0.43 0.0764 0.1119 1496837 Maybridge3_003736 O=S(=O)(c1ccccc1)n2ccc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J19 compound treatment 0.344 0.0246 1.98 0.346 0.0243 2.21 2.9627 0.9986 2077130 Maybridge3_003737 COc1ccc(NC=C2C(=O)CC(CC2=O)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J20 compound treatment 0.359 0.0396 3.19 0.353 0.0313 2.84 4.2661 0.9983 2077131 Maybridge3_003738 FC(F)(F)c1cccc(c1)S(=O)(=O)CCSc2ncccc2C(=O)NCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J21 compound treatment 0.339 0.0196 1.58 0.346 0.0243 2.21 2.678 0.9866 2077132 Maybridge3_003739 CCCS(=O)(=O)/C(=C/Nc1ccc2OCCOc2c1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J22 compound treatment 0.334 0.0146 1.18 0.34 0.0183 1.66 2.0081 0.9858 1126293 Maybridge3_003740 OCCSc1nccnc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J23 mock treatment 0.32 6.25E-4 0.05 0.322 3.12E-4 0.03 0.0556 0.9632 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 J24 positive control 0.088 -0.231 -18.63 0.089 -0.233 -21.12 -28.1098 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K01 compound treatment 0.328 0.00862 0.69 0.331 0.00931 0.85 1.0888 0.9952 2077133 Maybridge3_003741 NC(=O)c1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K02 compound treatment 0.324 0.00462 0.37 0.335 0.0133 1.21 1.1178 0.884 2077134 Maybridge3_003742 CSc1sc(cc1C#N)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K03 compound treatment 0.322 0.00262 0.21 0.334 0.0123 1.12 0.9397 0.8262 2077135 Maybridge3_003743 N/C(=N\O)/c1cccc(CS(=O)(=O)c2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K04 compound treatment 0.321 0.00162 0.13 0.332 0.0103 0.94 0.7544 0.7982 1305959 Maybridge3_003744 CC(C)(C)c1c(C#N)sc2sc(C#N)c(N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K05 compound treatment 0.331 0.0116 0.94 0.337 0.0153 1.39 1.6448 0.9815 1658284 Maybridge3_003745 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K06 compound treatment 0.33 0.0106 0.86 0.332 0.0103 0.94 1.2669 0.999 2077136 Maybridge3_003746 CCOC(=O)c1sc(c(C=C)c1C)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K07 compound treatment 0.324 0.00462 0.37 0.334 0.0123 1.12 1.0536 0.8944 2077137 Maybridge3_003747 CS(=O)(=O)c1scc(c1C#N)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K08 compound treatment 0.325 0.00562 0.45 0.334 0.0123 1.12 1.1106 0.9209 1170090 Maybridge3_003748 CNC(=O)c1sc(c(C=C)c1C)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K09 compound treatment 0.317 -0.00238 -0.19 0.32 -0.00169 -0.15 -0.2435 -0.9939 2077138 Maybridge3_003749 Fc1ccc(NC(=O)CSc2cccs2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K10 compound treatment 0.329 0.00962 0.78 0.333 0.0113 1.03 1.2741 0.9904 2077139 Maybridge3_003750 CC(C)(C)c1csc(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K11 compound treatment 0.33 0.0106 0.86 0.334 0.0123 1.12 1.3953 0.9913 1669879 Maybridge3_003751 COc1ccc(cc1)S(=O)(=O)N=S(=O)(C)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K12 compound treatment 0.333 0.0136 1.1 0.336 0.0143 1.3 1.6945 0.9965 2077140 Maybridge3_003752 Cc1nn(Cc2nnc(o2)c3cccs3)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K13 compound treatment 0.329 0.00962 0.78 0.339 0.0173 1.57 1.6593 0.9469 2077141 Maybridge3_003753 OC(=O)c1sc(N2CCOCC2)c(C#N)c1c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K14 compound treatment 0.331 0.0116 0.94 0.339 0.0173 1.57 1.7731 0.9694 1328852 Maybridge3_003754 CSc1sc(C#N)c-2c1S(=O)(=O)N(C)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K15 compound treatment 0.32 6.25E-4 0.05 0.321 -6.88E-4 -0.06 -0.0085 -0.1065 1462245 Maybridge3_003755 Clc1ccc(cc1)c2csc(CS(=O)(=O)c3cccs3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K16 compound treatment 0.345 0.0256 2.06 0.338 0.0163 1.48 2.5061 0.9867 2077142 Maybridge3_003756 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)n3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K17 compound treatment 0.349 0.0296 2.39 0.353 0.0313 2.84 3.6967 0.9962 2077143 Maybridge3_003757 O=S(=O)(Cc1ccco1)/C(=C/Nc2ccccn2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K18 compound treatment 0.336 0.0166 1.34 0.339 0.0173 1.57 2.0578 0.9968 2077144 Maybridge3_003758 CN(C)S(=O)(=O)c1ccc(s1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K19 compound treatment 0.335 0.0156 1.26 0.335 0.0133 1.21 1.7442 0.9998 2077145 Maybridge3_003759 Cc1nnsc1C(=O)N=S(=O)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K20 compound treatment 0.362 0.0426 3.43 0.357 0.0353 3.21 4.6936 0.9994 2077146 Maybridge3_003760 Cc1cc(C)n(n1)S(=O)(=O)c2ccc(s2)c3cc(n(C)n3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K21 compound treatment 0.331 0.0116 0.94 0.335 0.0133 1.21 1.5164 0.992 2077147 Maybridge3_003761 CSc1ncc(c(N)n1)S(=O)(=O)Cc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K22 compound treatment 0.338 0.0186 1.5 0.351 0.0293 2.66 2.9419 0.9632 2077148 Maybridge3_003762 CN1c2ccsc2C(=O)/C(=C\Nc3ccc(F)cc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K23 mock treatment 0.321 0.00162 0.13 0.322 3.12E-4 0.03 0.1126 0.8409 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 K24 positive control 0.089 -0.23 -18.55 0.091 -0.231 -20.94 -27.9244 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L01 compound treatment 0.326 0.00662 0.53 0.332 0.0103 0.94 1.0391 0.9645 2077149 Maybridge3_003763 Cc1c(Br)sc2sc(c(C)c12)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L02 compound treatment 0.317 -0.00238 -0.19 0.327 0.00531 0.48 0.2057 0.3966 2077150 Maybridge3_003764 Clc1ccc(SCc2cccc(c2)C(=O)CC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L03 compound treatment 0.32 6.25E-4 0.05 0.336 0.0143 1.3 0.9542 0.7339 2077151 Maybridge3_003765 CC(C)(C)c1csc(n1)c2ccc(/C=C(\C#N)/S(=O)(=O)C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L04 compound treatment 0.331 0.0116 0.94 0.345 0.0233 2.12 2.1583 0.9327 2077152 Maybridge3_003766 O=S(=O)(Cc1ccco1)/C(=C/N2CCc3ccccc23)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L05 compound treatment 0.332 0.0126 1.02 0.334 0.0123 1.12 1.5092 0.9989 2077153 Maybridge3_003767 CN1c2sc(C)c(C)c2C(=O)/C(=C\Nc3ccc(Cl)cn3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L06 compound treatment 0.334 0.0146 1.18 0.338 0.0163 1.48 1.8798 0.9936 2077154 Maybridge3_003768 FC(F)(F)c1cc(n2ncc(C(=O)Nc3ccc(Cl)cc3)c2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L07 compound treatment 0.363 0.0436 3.51 0.367 0.0453 4.11 5.3924 0.9969 2077155 Maybridge3_003769 CN(C)n1cccc1/C=C(\C#N)/S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L08 compound treatment 0.342 0.0226 1.82 0.339 0.0173 1.57 2.3995 0.9973 1130719 Maybridge3_003770 CSc1sc(c2cc[nH]n2)c(c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L09 compound treatment 0.333 0.0136 1.1 0.341 0.0193 1.75 2.0154 0.9745 2077156 Maybridge3_003771 O=C1CC(SC(=C1)SCC#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L10 compound treatment 0.337 0.0176 1.42 0.345 0.0233 2.12 2.4999 0.9811 2077157 Maybridge3_003772 CNC(=O)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L11 compound treatment 0.335 0.0156 1.26 0.34 0.0183 1.66 2.0651 0.9906 1321946 Maybridge3_003773 CCOC(=O)c1sc(N2CCCC2)c3C(=O)CC(C)(C)Cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L12 compound treatment 0.324 0.00462 0.37 0.34 0.0183 1.66 1.4387 0.8446 2077158 Maybridge3_003774 CS(=O)(=O)c1ccsc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L13 compound treatment 0.327 0.00762 0.61 0.334 0.0123 1.12 1.2245 0.9602 1647807 Maybridge3_003775 CC1(C)CC(=O)c2c(NCc3ccco3)sc(C#N)c2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L14 compound treatment 0.323 0.00362 0.29 0.332 0.0103 0.94 0.8683 0.8856 2077159 Maybridge3_003776 FC(F)(F)c1ccc(nc1)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L15 compound treatment 0.323 0.00362 0.29 0.329 0.00731 0.66 0.6758 0.9319 2077160 Maybridge3_003777 Nc1cc(nn1c2ccc(Cl)cc2)c3ccc(OC(F)(F)F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L16 compound treatment 0.34 0.0206 1.66 0.342 0.0203 1.84 2.4782 0.9986 2077161 Maybridge3_003778 Cc1c(C(=O)O)c(C(=O)O)c2SCCn12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L17 compound treatment 0.34 0.0206 1.66 0.34 0.0183 1.66 2.3498 1.0 2077162 Maybridge3_003779 CSc1nc(nc(c2ccco2)c1C#N)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L18 compound treatment 0.326 0.00662 0.53 0.327 0.00531 0.48 0.7182 0.9987 1693089 Maybridge3_003780 O=S(=O)(c1cccs1)n2ccc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L19 compound treatment 0.328 0.00862 0.69 0.333 0.0113 1.03 1.2172 0.9819 2077163 Maybridge3_003781 CC(C)c1ncc(c(N)n1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L20 compound treatment 0.342 0.0226 1.82 0.335 0.0133 1.21 2.1428 0.9801 2077164 Maybridge3_003782 OC(=O)c1ccc(CS(=O)(=O)c2ccc(cn2)C(F)(F)F)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L21 compound treatment 0.331 0.0116 0.94 0.338 0.0163 1.48 1.709 0.9755 2077165 Maybridge3_003783 CC1(C)CCc2cc(/C=N/O)ccc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L22 compound treatment 0.338 0.0186 1.5 0.341 0.0193 1.75 2.3001 0.997 1187489 Maybridge3_003784 OCCS(=O)(=O)c1nccnc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L23 mock treatment 0.326 0.00662 0.53 0.325 0.00331 0.3 0.5898 0.9632 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 L24 positive control 0.09 -0.229 -18.47 0.092 -0.23 -20.85 -27.8033 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M01 compound treatment 0.325 0.00562 0.45 0.33 0.00831 0.75 0.8538 0.9702 2077166 Maybridge3_003785 CCCS(=O)(=O)c1csc(C(=O)OC)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M02 compound treatment 0.322 0.00262 0.21 0.328 0.00631 0.57 0.5546 0.9081 2077167 Maybridge3_003786 CCOC(=O)c1sc2sc(C(=O)OCC)c(C)c2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M03 compound treatment 0.324 0.00462 0.37 0.331 0.00931 0.85 0.8611 0.9322 2077168 Maybridge3_003787 Oc1nc(nc2CSCc21)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M04 compound treatment 0.328 0.00862 0.69 0.34 0.0183 1.66 1.6665 0.9251 2077169 Maybridge3_003788 Cc1csc2sc(/C=C(\C#N)/S(=O)(=O)C)c(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M05 compound treatment 0.342 0.0226 1.82 0.356 0.0343 3.11 3.4906 0.9674 1685383 Maybridge3_003789 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M06 compound treatment 0.332 0.0126 1.02 0.333 0.0113 1.03 1.445 1.0 2077170 Maybridge3_003790 CC(C)(C)S(=O)(=O)/C(=C/Nc1ccc(OC(F)(F)F)cc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M07 compound treatment 0.295 -0.0244 -1.96 0.3 -0.0217 -1.97 -2.7799 -1.0 2077171 Maybridge3_003791 CSc1scc(c1C#N)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M08 compound treatment 0.326 0.00662 0.53 0.331 0.00931 0.85 0.975 0.9754 2077172 Maybridge3_003792 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M09 compound treatment 0.315 -0.00438 -0.35 0.323 0.00131 0.12 -0.1649 -0.4433 2077173 Maybridge3_003793 CC(C)c1ccc(NC(=O)CSc2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M10 compound treatment 0.328 0.00862 0.69 0.327 0.00531 0.48 0.8321 0.9841 1544695 Maybridge3_003794 CC1(C)CC(=O)c2c(sc(C(=O)OCc3ccccc3)c2C1)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M11 compound treatment 0.323 0.00362 0.29 0.329 0.00731 0.66 0.6758 0.9319 2077174 Maybridge3_003795 CS(=O)(=NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M12 compound treatment 0.33 0.0106 0.86 0.326 0.00431 0.39 0.8818 0.9372 2077175 Maybridge3_003796 CS(=O)(=O)c1sc(Br)c2CCCC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M13 compound treatment 0.315 -0.00438 -0.35 0.316 -0.00569 -0.52 -0.6142 -0.9826 2077176 Maybridge3_003797 CN(C)c1scc(c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M14 compound treatment 0.324 0.00462 0.37 0.331 0.00931 0.85 0.8611 0.9322 2077177 Maybridge3_003798 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC2CCSC2=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M15 compound treatment 0.327 0.00762 0.61 0.325 0.00331 0.3 0.6468 0.946 1145601 Maybridge3_003799 CC(C)(C)c1csc(CS(=O)(=O)c2cccs2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M16 compound treatment 0.334 0.0146 1.18 0.329 0.00731 0.66 1.3021 0.9632 2077178 Maybridge3_003800 CC1(C)CC(=O)C=C(SCc2ccc(Cl)cc2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M17 compound treatment 0.33 0.0106 0.86 0.331 0.00931 0.85 1.2027 1.0 2077179 Maybridge3_003801 N/C(=N\O)/CS(=O)(=O)Cc1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M18 compound treatment 0.332 0.0126 1.02 0.336 0.0143 1.3 1.6375 0.9926 2077180 Maybridge3_003802 CC1(C)CC(=O)C=C(SCC(=O)c2ccc(Cl)cc2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M19 compound treatment 0.33 0.0106 0.86 0.333 0.0113 1.03 1.3311 0.9959 2077181 Maybridge3_003803 COC(=O)c1cc(cs1)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M20 compound treatment 0.346 0.0266 2.14 0.34 0.0183 1.66 2.6914 0.9921 1442462 Maybridge3_003804 Cc1ccc(cc1)S(=O)(=O)CCN(Cc2cccnc2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M21 compound treatment 0.323 0.00362 0.29 0.33 0.00831 0.75 0.7399 0.9146 1546264 Maybridge3_003805 CSc1sc(C(=O)c2ccc(Cl)cc2)c3CCCC(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M22 compound treatment 0.336 0.0166 1.34 0.335 0.0133 1.21 1.8011 0.9987 2077182 Maybridge3_003806 CN1c2ccsc2C(=O)/C(=C\Nc3ccccc3Cl)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M23 mock treatment 0.318 -0.00138 -0.11 0.316 -0.00569 -0.52 -0.4433 -0.8397 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 M24 positive control 0.09 -0.229 -18.47 0.093 -0.229 -20.76 -27.7391 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N01 compound treatment 0.339 0.0196 1.58 0.347 0.0253 2.3 2.7421 0.9833 2077183 Maybridge3_003807 CSc1sc(cc1c2nc(cs2)c3ccc(Cl)cc3)C(=O)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N02 compound treatment 0.338 0.0186 1.5 0.341 0.0193 1.75 2.3001 0.997 2077184 Maybridge3_003808 CN1c2ccccc2C(=O)/C(=C/N=S(=O)(C)c3ccccc3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N03 compound treatment 0.339 0.0196 1.58 0.332 0.0103 0.94 1.7794 0.9688 1180077 Maybridge3_003809 CSc1sc(C(=O)O)c2-c3sccc3N(C)S(=O)(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N04 compound treatment 0.326 0.00662 0.53 0.335 0.0133 1.21 1.2317 0.9325 2077185 Maybridge3_003810 FC(F)(F)c1ccc(nc1)S(=O)(=O)/C(=C/N2CCc3ccccc23)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N05 compound treatment 0.338 0.0186 1.5 0.339 0.0173 1.57 2.1717 0.9997 2077186 Maybridge3_003811 CC(C)(C)C(=O)CSC1=CC(=O)CC(S1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N06 compound treatment 0.335 0.0156 1.26 0.336 0.0143 1.3 1.8083 0.9999 2077187 Maybridge3_003812 CSc1sc(c2ccon2)c(c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N07 compound treatment 0.379 0.0596 4.8 0.368 0.0463 4.2 6.3677 0.9978 2077188 Maybridge3_003813 CN(C)n1cccc1/C=C(\C#N)/S(=O)(=O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N08 compound treatment 0.344 0.0246 1.98 0.355 0.0333 3.02 3.5403 0.9791 1131660 Maybridge3_003814 Clc1ccc(NC(=O)c2cc3ccccc3o2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N09 compound treatment 0.328 0.00862 0.69 0.337 0.0153 1.39 1.4739 0.9486 2077189 Maybridge3_003815 Cn1c(CSc2cccs2)nnc1SCC(=O)Nc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N10 compound treatment 0.336 0.0166 1.34 0.34 0.0183 1.66 2.122 0.9942 2077190 Maybridge3_003816 CS(=O)(=NC(=O)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N11 compound treatment 0.328 0.00862 0.69 0.34 0.0183 1.66 1.6665 0.9251 2077191 Maybridge3_003817 FC(F)(F)c1cccc(c1)C(=O)c2cc3cc(Cl)ccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N12 compound treatment 0.3 -0.0194 -1.56 0.298 -0.0237 -2.15 -2.6236 -0.9876 2077192 Maybridge3_003818 FC(F)(F)c1cccc(SCc2cccc(c2)C(=O)CC#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N13 compound treatment 0.332 0.0126 1.02 0.332 0.0103 0.94 1.3808 0.9991 2077193 Maybridge3_003819 COC(=O)C1=C(CSC1)Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N14 compound treatment 0.339 0.0196 1.58 0.346 0.0243 2.21 2.678 0.9866 2077194 Maybridge3_003820 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)/N=S/2\CCC3(C2)OCCO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N15 compound treatment 0.332 0.0126 1.02 0.33 0.00831 0.75 1.2524 0.9892 1387347 Maybridge3_003821 CS(=O)(=O)c1sc(C(=O)N)c2CCC=Cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N16 compound treatment 0.348 0.0286 2.31 0.347 0.0253 2.3 3.2546 1.0 2077195 Maybridge3_003822 CC(C)CNC(=O)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N17 compound treatment 0.356 0.0366 2.95 0.357 0.0353 3.21 4.352 0.9991 2077196 Maybridge3_003823 COC(=O)c1sc2ncccc2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N18 compound treatment 0.355 0.0356 2.87 0.348 0.0263 2.39 3.7174 0.9959 2077197 Maybridge3_003824 O=C(c1cccs1)n2ccc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N19 compound treatment 0.333 0.0136 1.1 0.335 0.0133 1.21 1.6303 0.9988 2077198 Maybridge3_003825 COC(=O)c1sccc1NC=C2C(=O)CC(CC2=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N20 compound treatment 0.371 0.0516 4.16 0.372 0.0503 4.57 6.1689 0.9989 2077199 Maybridge3_003826 CS(=O)(=O)CCSc1ncccc1C(=O)Sc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N21 compound treatment 0.353 0.0336 2.71 0.35 0.0283 2.57 3.7319 0.9997 1433008 Maybridge3_003827 CCOC(=O)c1sc(SCCO)c2C(=O)CC(C)(C)Cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N22 compound treatment 0.334 0.0146 1.18 0.339 0.0173 1.57 1.944 0.9899 1191322 Maybridge3_003828 Cc1nn(Cc2cccc(c2)C(=O)N)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N23 mock treatment 0.322 0.00262 0.21 0.323 0.00131 0.12 0.2337 0.9632 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 N24 positive control 0.09 -0.229 -18.47 0.093 -0.229 -20.76 -27.7391 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O01 compound treatment 0.338 0.0186 1.5 0.344 0.0223 2.03 2.4927 0.9891 2077200 Maybridge3_003829 N/C(=N\O)/CSc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O02 compound treatment 0.354 0.0346 2.79 0.36 0.0383 3.48 4.4307 0.994 2077201 Maybridge3_003830 CSc1sc(c2cc[nH]n2)c3CC(C)(C)CC(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O03 compound treatment 0.33 0.0106 0.86 0.338 0.0163 1.48 1.652 0.966 2077202 Maybridge3_003831 Cc1ccc(cc1)S(=O)(=O)CCS(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O04 compound treatment 0.33 0.0106 0.86 0.368 0.0463 4.2 3.5776 0.8339 2077203 Maybridge3_003832 CSc1sc(C#N)c2CCC/C(=N/O)/c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O05 compound treatment 0.326 0.00662 0.53 0.33 0.00831 0.75 0.9108 0.9856 1199500 Maybridge3_003833 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O06 compound treatment 0.345 0.0256 2.06 0.35 0.0283 2.57 3.2763 0.9941 2077204 Maybridge3_003834 COC(=O)c1cc(c(SC)s1)c2nc(C)cs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O07 compound treatment 0.342 0.0226 1.82 0.345 0.0233 2.12 2.7846 0.9972 2077205 Maybridge3_003835 CC(C)S(=O)(=O)c1cnc(nc1N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O08 compound treatment 0.349 0.0296 2.39 0.348 0.0263 2.39 3.3757 1.0 2077206 Maybridge3_003836 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O09 compound treatment 0.337 0.0176 1.42 0.342 0.0203 1.84 2.3073 0.9916 1270241 Maybridge3_003837 CC(C)S(=O)(=O)c1cnc(N)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O10 compound treatment 0.349 0.0296 2.39 0.344 0.0223 2.03 3.119 0.9967 2077207 Maybridge3_003838 Cc1nn(Cc2nnc(o2)c3ccccc3Cl)c(C)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O11 compound treatment 0.336 0.0166 1.34 0.339 0.0173 1.57 2.0578 0.9968 2077208 Maybridge3_003839 CC(C)S(=O)(=O)c1cscc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O12 compound treatment 0.338 0.0186 1.5 0.346 0.0243 2.21 2.621 0.9823 2077209 Maybridge3_003840 CCOC(=O)c1csc(Cn2nc(C)c(Br)c2C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O13 compound treatment 0.332 0.0126 1.02 0.339 0.0173 1.57 1.8301 0.9778 2077210 Maybridge3_003841 CSc1nnc(c2ccc(Br)s2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O14 compound treatment 0.331 0.0116 0.94 0.336 0.0143 1.3 1.5806 0.9871 2077211 Maybridge3_003842 CSc1scc2CCc3cn(nc3-c12)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O15 compound treatment 0.317 -0.00238 -0.19 0.323 0.00131 0.12 -0.051 -0.2263 1402498 Maybridge3_003843 O=C(Cc1cccc(CC(=O)c2ccccc2)c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O16 compound treatment 0.335 0.0156 1.26 0.337 0.0153 1.39 1.8725 0.9988 1540080 Maybridge3_003844 CCCS(=O)(=O)C1=C(N)OC(=C(C#N)C1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O17 compound treatment 0.338 0.0186 1.5 0.341 0.0193 1.75 2.3001 0.997 2077212 Maybridge3_003845 Cn1c(SCc2cccc(C#N)c2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O18 compound treatment 0.36 0.0406 3.27 0.366 0.0443 4.02 5.1574 0.9947 2077213 Maybridge3_003846 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)Nc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O19 compound treatment 0.356 0.0366 2.95 0.355 0.0333 3.02 4.2236 0.9999 2077214 Maybridge3_003847 CCOC(=O)c1sc(SCc2ccccc2)c(c1N)S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O20 compound treatment 0.346 0.0266 2.14 0.344 0.0223 2.03 2.9482 0.9996 1490245 Maybridge3_003848 CN(CCS(=O)(=O)c1ccc(C)cc1)Cc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O21 compound treatment 0.337 0.0176 1.42 0.34 0.0183 1.66 2.179 0.9969 1198188 Maybridge3_003849 CCOC(=O)c1sc(c2C(=O)CC(C)(C)Cc12)S(=O)(=O)Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O22 compound treatment 0.353 0.0336 2.71 0.354 0.0323 2.93 3.9886 0.9992 2077215 Maybridge3_003850 CN1c2ccsc2C(=O)/C(=C\Nc3ccccn3)/S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O23 mock treatment 0.331 0.0116 0.94 0.328 0.00631 0.57 1.0671 0.9722 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 O24 positive control 0.091 -0.228 -18.39 0.092 -0.23 -20.85 -27.7464 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P01 compound treatment 0.335 0.0156 1.26 0.34 0.0183 1.66 2.0651 0.9906 1585092 Maybridge3_003851 CCOC(=O)c1c(C)nsc1NC(=O)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P02 compound treatment 0.4 0.0806 6.49 0.395 0.0733 6.65 9.2964 0.9999 2077216 Maybridge3_003852 Cn1nc(cc1C(F)(F)F)c2ccc(/C=C(\C#N)/S(=O)(=O)C)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P03 compound treatment 0.342 0.0226 1.82 0.353 0.0313 2.84 3.2981 0.9769 2077217 Maybridge3_003853 COc1ccc(N/C=C/2\C(=O)c3c(C)c(C)sc3N(C)S2(=O)=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P04 compound treatment 0.325 0.00562 0.45 0.333 0.0113 1.03 1.0464 0.9323 2077218 Maybridge3_003854 CSc1nc(nc(c2ccco2)c1C#N)n3nc(C)cc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P05 compound treatment 0.368 0.0486 3.92 0.36 0.0383 3.48 5.2278 0.9983 2077219 Maybridge3_003855 CC(C)NC(=O)CSc1nccc(n1)c2sc3scc(C)c3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P06 compound treatment 0.333 0.0136 1.1 0.333 0.0113 1.03 1.5019 0.9995 1347197 Maybridge3_003856 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)N=S(=O)(C)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P07 compound treatment 0.454 0.135 10.84 0.46 0.138 12.55 16.5433 0.9973 2077220 Maybridge3_003857 CN(C)n1cccc1/C=C(\C#N)/S(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P08 compound treatment 0.329 0.00962 0.78 0.334 0.0123 1.12 1.3383 0.984 1307631 Maybridge3_003858 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P09 compound treatment 0.332 0.0126 1.02 0.335 0.0133 1.21 1.5733 0.9963 2077221 Maybridge3_003859 Cn1c(CSc2cccs2)nnc1SCC(=O)NCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P10 compound treatment 0.328 0.00862 0.69 0.332 0.0103 0.94 1.153 0.9892 2077222 Maybridge3_003860 Clc1ccc(cc1)c2ccnc(SCCS(=O)(=O)c3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P11 compound treatment 0.34 0.0206 1.66 0.342 0.0203 1.84 2.4782 0.9986 1293251 Maybridge3_003861 CC1(C)CC(=O)c2cnc(SCCS(=O)(=O)c3ccc(Cl)cc3)nc2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P12 compound treatment 0.35 0.0306 2.47 0.352 0.0303 2.75 3.6894 0.9985 2077223 Maybridge3_003862 COC(=O)CSc1nccc(n1)c2ccc3OC(C)(C)CCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P13 compound treatment 0.335 0.0156 1.26 0.336 0.0143 1.3 1.8083 0.9999 2077224 Maybridge3_003863 Cc1cc2ncc(c(C)n2n1)c3ccnc(SCC(=O)c4ccc(Cl)cc4)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P14 compound treatment 0.333 0.0136 1.1 0.333 0.0113 1.03 1.5019 0.9995 2077225 Maybridge3_003864 OC(=O)Cc1ccc(s1)C(=O)CSc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P15 compound treatment 0.366 0.0466 3.75 0.366 0.0443 4.02 5.4991 0.9994 2077226 Maybridge3_003865 CCSc1sc(C(=O)OC)c2CC(C)(C)C/C(=N\O)/c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P16 compound treatment 0.336 0.0166 1.34 0.336 0.0143 1.3 1.8653 0.9999 2077227 Maybridge3_003866 COC(=O)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P17 compound treatment 0.329 0.00962 0.78 0.33 0.00831 0.75 1.0816 0.9999 2077228 Maybridge3_003867 Clc1ccc(cc1)S(=O)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P18 compound treatment 0.32 6.25E-4 0.05 0.332 0.0103 0.94 0.6975 0.7441 2077229 Maybridge3_003868 CCOC(=O)c1cnc(SCC(=O)c2ccc(Cl)cc2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P19 compound treatment 0.329 0.00962 0.78 0.335 0.0133 1.21 1.4025 0.977 2077230 Maybridge3_003869 CCOC(=O)c1c(C)c(C)sc1NC=C2C(=O)CC(CC2=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P20 compound treatment 0.341 0.0216 1.74 0.345 0.0233 2.12 2.7277 0.9953 2077231 Maybridge3_003870 FC(F)(F)c1ccc(SCc2ccc(o2)C(=O)Nc3ccccc3)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P21 compound treatment 0.337 0.0176 1.42 0.34 0.0183 1.66 2.179 0.9969 2077232 Maybridge3_003871 CN(C)S(=O)(=O)c1cc(c(Cl)s1)S(=O)(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P22 compound treatment 0.327 0.00762 0.61 0.332 0.0103 0.94 1.0961 0.9791 2077233 Maybridge3_003872 FC(F)(F)Oc1ccc(NS(=O)(=O)c2cccc3nsnc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P23 mock treatment 0.323 0.00362 0.29 0.322 3.12E-4 0.03 0.2265 0.7722 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1441 P24 positive control 0.092 -0.227 -18.31 0.092 -0.23 -20.85 -27.6894 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A01 compound treatment 0.309 -0.00156 -0.13 0.311 0.00475 0.43 0.2159 0.4807 2077234 Maybridge3_003873 N/C(=N/O)/c1nccnc1Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A02 compound treatment 0.305 -0.00556 -0.45 0.312 0.00575 0.52 0.0523 0.0761 2077235 Maybridge3_003874 CSC(C)c1ccn(n1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A03 compound treatment 0.309 -0.00156 -0.13 0.305 -0.00125 -0.11 -0.1692 -0.9987 1138417 Maybridge3_003875 Cc1onc(c1C(=O)Nc2cccc3nsnc23)c4ccccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A04 compound treatment 0.306 -0.00456 -0.37 0.309 0.00275 0.25 -0.0833 -0.1875 2077236 Maybridge3_003876 N/C(=N\O)/c1nccnc1Oc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A05 compound treatment 0.302 -0.00856 -0.69 0.307 7.5E-4 0.07 -0.4394 -0.6342 1656884 Maybridge3_003877 Cn1nc(cc1NC(=O)C2COc3ccccc3O2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A06 compound treatment 0.312 0.00144 0.12 0.317 0.0107 0.98 0.7718 0.7855 2077237 Maybridge3_003878 COC(=O)CSc1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A07 compound treatment 0.31 -5.63E-4 -0.05 0.311 0.00475 0.43 0.2728 0.6294 2077238 Maybridge3_003879 Cn1cnc(c1)S(=O)(=O)N=S(=O)(C)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A08 compound treatment 0.305 -0.00556 -0.45 0.305 -0.00125 -0.11 -0.397 -0.8591 1063968 Maybridge3_003880 C(c1ccccc1)n2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A09 compound treatment 0.287 -0.0236 -1.9 0.289 -0.0173 -1.57 -2.4489 -0.9954 1573915 Maybridge3_003881 O=C(Oc1ccccc1)c2csc(n2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A10 compound treatment 0.301 -0.00956 -0.77 0.303 -0.00325 -0.3 -0.7531 -0.9133 2077239 Maybridge3_003882 O=S(=O)(C1CS(=O)(=O)c2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A11 compound treatment 0.307 -0.00356 -0.29 0.299 -0.00725 -0.66 -0.6682 -0.9308 1240503 Maybridge3_003883 O=C(Oc1ccccc1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A12 compound treatment 0.325 0.0144 1.16 0.321 0.0147 1.34 1.7688 0.9975 2077240 Maybridge3_003884 COc1cc(nc2ccc(C)c(N)c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A13 compound treatment 0.31 -5.63E-4 -0.05 0.307 7.5E-4 0.07 0.0161 0.197 2077241 Maybridge3_003885 Cn1c(SCc2ccc(Br)cc2F)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A14 compound treatment 0.309 -0.00156 -0.13 0.305 -0.00125 -0.11 -0.1692 -0.9987 2077242 Maybridge3_003886 COc1cc(nc2ccc(C)c(NC(=O)c3ccccc3)c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A15 compound treatment 0.31 -5.63E-4 -0.05 0.306 -2.5E-4 -0.02 -0.0481 -0.9489 1654432 Maybridge3_003887 Brc1cc2CCOc2c(c1)C(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A16 compound treatment 0.306 -0.00456 -0.37 0.301 -0.00525 -0.48 -0.5968 -0.9917 2077243 Maybridge3_003888 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ncccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A17 compound treatment 0.31 -5.63E-4 -0.05 0.305 -0.00125 -0.11 -0.1123 -0.9189 1415267 Maybridge3_003889 N#CCOc1ccc2nonc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A18 compound treatment 0.305 -0.00556 -0.45 0.304 -0.00225 -0.2 -0.4611 -0.9367 2077244 Maybridge3_003890 O=S(=O)(/C(=C/NC1CCN(Cc2ccccc2)CC1)/C#N)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A19 compound treatment 0.312 0.00144 0.12 0.309 0.00275 0.25 0.2584 0.939 1645474 Maybridge3_003891 Clc1ccc(C(=O)Oc2ccc3c(=O)ccoc3c2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A20 compound treatment 0.316 0.00544 0.44 0.313 0.00675 0.61 0.7429 0.9864 1580603 Maybridge3_003892 O=S(=O)(CCN1CCC(CC1)n2cccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A21 compound treatment 0.319 0.00844 0.68 0.315 0.00875 0.79 1.0421 0.997 2077245 Maybridge3_003893 COC(=O)c1scc2c(OC)cc(nc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A22 compound treatment 0.321 0.0104 0.84 0.321 0.0147 1.34 1.541 0.9748 1330270 Maybridge3_003894 O=C(Nc1ccc(cc1)N2CCC(CC2)n3cccc3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A23 mock treatment 0.303 -0.00756 -0.61 0.299 -0.00725 -0.66 -0.896 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 A24 positive control 0.083 -0.228 -18.32 0.082 -0.224 -20.36 -27.3511 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B01 compound treatment 0.325 0.0144 1.16 0.324 0.0177 1.61 1.9614 0.9872 2077246 Maybridge3_003895 CSc1nn(cc1C(=O)Sc2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B02 compound treatment 0.331 0.0204 1.65 0.33 0.0238 2.16 2.6881 0.9911 1229384 Maybridge3_003896 COc1c(I)cc(Cl)c2cccnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B03 compound treatment 0.358 0.0474 3.82 0.351 0.0447 4.06 5.5734 0.9995 1462132 Maybridge3_003897 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1N(C)CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B04 compound treatment 0.326 0.0154 1.24 0.323 0.0168 1.52 1.9541 0.995 2077247 Maybridge3_003898 FC(F)(F)c1cccc(NC(=O)c2ccc3ncccc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B05 compound treatment 0.334 0.0234 1.89 0.331 0.0248 2.25 2.9231 0.9962 2077248 Maybridge3_003899 Cc1ccc2nc(cc(N3CCN(CCS(=O)(=O)c4ccc(Cl)cc4)CC3)c2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B06 compound treatment 0.33 0.0194 1.57 0.328 0.0217 1.97 2.5028 0.9934 2077249 Maybridge3_003900 FC(F)(F)c1c2CCCc2nc3cc(nn13)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B07 compound treatment 0.321 0.0104 0.84 0.315 0.00875 0.79 1.1559 0.9996 1557957 Maybridge3_003901 O=C(Oc1ccccc1)c2c(nnc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B08 compound treatment 0.348 0.0374 3.01 0.346 0.0398 3.61 4.6831 0.996 2077250 Maybridge3_003902 CCOC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B09 compound treatment 0.335 0.0244 1.97 0.327 0.0208 1.88 2.7233 0.9998 2077251 Maybridge3_003903 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B10 compound treatment 0.333 0.0224 1.81 0.326 0.0198 1.79 2.5453 1.0 2077252 Maybridge3_003904 FC(F)(F)c1cc(N2CCN(CCOC(=O)C3CC3)CC2)c4cccc(Cl)c4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B11 compound treatment 0.324 0.0134 1.08 0.319 0.0127 1.16 1.5835 0.9994 2077253 Maybridge3_003905 Oc1ccnc2ccc(OC(F)(F)F)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B12 compound treatment 0.329 0.0184 1.48 0.322 0.0158 1.43 2.0608 0.9998 1672604 Maybridge3_003906 O=C(N1CCOCC1)c2ccc3snnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B13 compound treatment 0.332 0.0214 1.73 0.321 0.0147 1.34 2.1674 0.9921 2077254 Maybridge3_003907 OC1(CC(=NO1)c2cccs2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B14 compound treatment 0.334 0.0234 1.89 0.325 0.0187 1.7 2.538 0.9987 2077255 Maybridge3_003908 Cc1ccc2nc(cc(N3CCC(CC3)C(=O)O)c2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B15 compound treatment 0.326 0.0154 1.24 0.319 0.0127 1.16 1.6974 0.9994 2077256 Maybridge3_003909 COc1ccc(cc1OC2CCCC2)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B16 compound treatment 0.329 0.0184 1.48 0.319 0.0127 1.16 1.8682 0.9924 1012681 Maybridge3_003910 OC(=O)CSc1ccnc2cc(Cl)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B17 compound treatment 0.334 0.0234 1.89 0.326 0.0198 1.79 2.6022 0.9997 2077257 Maybridge3_003911 Fc1cccc(OC(=O)c2ccc3nonc3c2)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B18 compound treatment 0.338 0.0274 2.21 0.331 0.0248 2.25 3.1509 1.0 2077258 Maybridge3_003912 CN(C(=O)c1cc2c(C)cc(C)cc2[nH]1)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B19 compound treatment 0.339 0.0284 2.29 0.332 0.0257 2.34 3.272 0.9999 2077259 Maybridge3_003913 CN(C)S(=O)(=O)c1ccc(s1)c2cc(on2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B20 compound treatment 0.329 0.0184 1.48 0.324 0.0177 1.61 2.1891 0.9992 1360569 Maybridge3_003914 CS(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B21 compound treatment 0.33 0.0194 1.57 0.324 0.0177 1.61 2.2461 0.9999 1729595 Maybridge3_003915 O=S(=O)(N1CCN(CC1)c2ccccc2)c3cccc4nsnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B22 compound treatment 0.337 0.0264 2.13 0.336 0.0297 2.7 3.4149 0.9931 2077260 Maybridge3_003916 C/C=C/C(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B23 mock treatment 0.314 0.00344 0.28 0.308 0.00175 0.16 0.3081 0.9652 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 B24 positive control 0.083 -0.228 -18.32 0.082 -0.224 -20.36 -27.3511 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C01 compound treatment 0.32 0.00944 0.76 0.319 0.0127 1.16 1.3557 0.9792 1646562 Maybridge3_003917 CS(=O)(=NS(=O)(=O)c1cccc2nsnc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C02 compound treatment 0.323 0.0124 1.0 0.319 0.0127 1.16 1.5266 0.9974 2077261 Maybridge3_003918 COC(=O)c1csc(c1OC)S(=O)(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C03 compound treatment 0.33 0.0194 1.57 0.326 0.0198 1.79 2.3744 0.9977 2077262 Maybridge3_003919 FC(F)(F)c1ccc(SCC(=O)Nc2cccc3nsnc23)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C04 compound treatment 0.321 0.0104 0.84 0.328 0.0217 1.97 1.9903 0.9276 1615428 Maybridge3_003920 COC(=O)c1csc(c1OC)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C05 compound treatment 0.329 0.0184 1.48 0.327 0.0208 1.88 2.3817 0.9931 2077263 Maybridge3_003921 N/C(=N\O)/c1ccc2nonc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C06 compound treatment 0.322 0.0114 0.92 0.322 0.0158 1.43 1.6622 0.9774 2077264 Maybridge3_003922 COC(=O)c1scc2c(Oc3ccccc3)cc(nc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C07 compound treatment 0.245 -0.0656 -5.28 0.253 -0.0532 -4.83 -7.151 -0.999 1678019 Maybridge3_003923 O=C(Sc1ccccn1)c2csc(n2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C08 compound treatment 0.328 0.0174 1.4 0.329 0.0227 2.07 2.4531 0.9823 2077265 Maybridge3_003924 Cn1c(SCc2nccn2Cc3ccc(Cl)cc3)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C09 compound treatment 0.319 0.00844 0.68 0.331 0.0248 2.25 2.069 0.8815 1626824 Maybridge3_003925 CCOC(=O)c1sc(nc1C)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C10 compound treatment 0.33 0.0194 1.57 0.314 0.00775 0.7 1.6042 0.9348 1922402 Maybridge3_003926 COC(=O)c1ccc(C#CC(C)(C)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C11 compound treatment 0.311 4.37E-4 0.04 0.318 0.0118 1.07 0.7791 0.7301 2077266 Maybridge3_003927 C(Sc1cccs1)c2ccc3nonc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C12 compound treatment 0.312 0.00144 0.12 0.297 -0.00925 -0.84 -0.5119 -0.6039 2077267 Maybridge3_003928 Clc1ccc(CSc2nccnc2C#N)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C13 compound treatment 0.32 0.00944 0.76 0.309 0.00275 0.25 0.7139 0.8925 2077268 Maybridge3_003929 Fc1cc(Br)ccc1CS(=O)(=O)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C14 compound treatment 0.342 0.0314 2.53 0.349 0.0428 3.88 4.534 0.9786 2077269 Maybridge3_003930 CCOC(=O)c1cncc(C#CCOC(=O)c2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C15 compound treatment 0.322 0.0114 0.92 0.314 0.00775 0.7 1.1487 0.9912 1249394 Maybridge3_003931 NC(=O)c1cc(Br)cc2CCOc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C16 compound treatment 0.326 0.0154 1.24 0.329 0.0227 2.07 2.3392 0.9705 2077270 Maybridge3_003932 NC(=O)C1CCN(CC1)c2cc(ccn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C17 compound treatment 0.325 0.0144 1.16 0.325 0.0187 1.7 2.0256 0.9827 2077271 Maybridge3_003933 CC(C)(C)c1csc(n1)c2ccc3nonc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C18 compound treatment 0.318 0.00744 0.6 0.312 0.00575 0.52 0.7926 0.9976 1266206 Maybridge3_003934 OCc1sccc1Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C19 compound treatment 0.344 0.0334 2.69 0.341 0.0348 3.15 4.1344 0.9969 2077272 Maybridge3_003935 CSc1nn2c(cc(nc2c1C(=O)O)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C20 compound treatment 0.116 -0.195 -15.67 0.113 -0.193 -17.54 -23.4823 -0.9984 2077273 Maybridge3_003936 FC(F)(F)c1nnc(SC(=O)c2ccc(C#Cc3ccccc3)o2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C21 compound treatment 0.318 0.00744 0.6 0.314 0.00775 0.7 0.9209 0.9968 2077274 Maybridge3_003937 FC(F)(F)c1cc(Oc2ccccc2)c3cccc(C#N)c3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C22 compound treatment 0.317 0.00644 0.52 0.32 0.0138 1.25 1.2491 0.9242 1735700 Maybridge3_003938 CCOC(=O)c1c(O)c2cc(Cl)ccc2nc1SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C23 mock treatment 0.313 0.00244 0.2 0.305 -0.00125 -0.11 0.0586 0.2583 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 C24 positive control 0.085 -0.226 -18.16 0.086 -0.22 -19.99 -26.9805 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D01 compound treatment 0.329 0.0184 1.48 0.328 0.0217 1.97 2.4459 0.9901 2077275 Maybridge3_003939 CSc1nn(cc1C(=O)Sc2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D02 compound treatment 0.329 0.0184 1.48 0.322 0.0158 1.43 2.0608 0.9998 1585459 Maybridge3_003940 Cc1occc1c2cc(N)n(n2)c3cccc(Cl)c3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D03 compound treatment 0.331 0.0204 1.65 0.329 0.0227 2.07 2.6239 0.9937 1370289 Maybridge3_003941 OC(=O)c1cncc(C#CCC2CCCCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D04 compound treatment 0.326 0.0154 1.24 0.327 0.0208 1.88 2.2109 0.9797 1614929 Maybridge3_003942 O=C(NCCc1ccccc1)c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D05 compound treatment 0.323 0.0124 1.0 0.324 0.0177 1.61 1.8475 0.9738 2077276 Maybridge3_003943 O=C(Nc1ccccc1)OCC#Cc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D06 compound treatment 0.32 0.00944 0.76 0.324 0.0177 1.61 1.6767 0.9412 2077277 Maybridge3_003944 Nc1nc(cc(n1)C(F)(F)F)c2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D07 compound treatment 0.358 0.0474 3.82 0.357 0.0508 4.61 5.9585 0.9957 1671972 Maybridge3_003945 COc1cc(NC(=O)c2c(nnc3ccccc23)c4ccccc4)cc(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D08 compound treatment 0.337 0.0264 2.13 0.334 0.0278 2.52 3.2865 0.9965 2077278 Maybridge3_003946 FC(F)(F)c1cc(nc2ccnn12)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D09 compound treatment 0.33 0.0194 1.57 0.329 0.0227 2.07 2.567 0.9907 1510085 Maybridge3_003947 COc1ccc(cc1OC)S(=O)(=O)NC2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D10 compound treatment 0.329 0.0184 1.48 0.319 0.0127 1.16 1.8682 0.9924 1241394 Maybridge3_003948 COC(=O)c1ccc2n(nnc2c1)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D11 compound treatment 0.331 0.0204 1.65 0.329 0.0227 2.07 2.6239 0.9937 1127976 Maybridge3_003949 O=S(=O)(N(CCC#N)Cc1cccs1)c2cccc3nsnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D12 compound treatment 0.344 0.0334 2.69 0.337 0.0308 2.79 3.8777 0.9998 2077279 Maybridge3_003950 C=CCn1c(SCC(=O)NCc2ccccc2)nnc1c3ccc4ncccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D13 compound treatment 0.336 0.0254 2.05 0.322 0.0158 1.43 2.4593 0.9845 1480094 Maybridge3_003951 Clc1cccc2c(ccnc12)N3CCC(CC3)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D14 compound treatment 0.321 0.0104 0.84 0.323 0.0168 1.52 1.6694 0.9609 2077280 Maybridge3_003952 Cn1c(CNC(=O)c2ccccc2)nnc1SCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D15 compound treatment 0.324 0.0134 1.08 0.32 0.0138 1.25 1.6477 0.9975 1558253 Maybridge3_003953 Fc1ccc(NC(=O)c2ccc3nonc3c2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D16 compound treatment 0.332 0.0214 1.73 0.335 0.0288 2.61 3.066 0.9799 1120418 Maybridge3_003954 CSc1nc2ccc(NC(=O)c3ccc4snnc4c3)cc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D17 compound treatment 0.332 0.0214 1.73 0.326 0.0198 1.79 2.4883 0.9998 1459416 Maybridge3_003955 O=C(N1CCN(CC1)c2ccccc2)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D18 compound treatment 0.327 0.0164 1.32 0.326 0.0198 1.79 2.2036 0.9889 1585700 Maybridge3_003956 COCC(C)NC(=O)c1cc2c(C)cc(C)cc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D19 compound treatment 0.352 0.0414 3.34 0.35 0.0437 3.97 5.1676 0.9963 1708839 Maybridge3_003957 N#Cc1nccnc1N2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D20 compound treatment 0.335 0.0244 1.97 0.332 0.0257 2.34 3.0443 0.9963 1732100 Maybridge3_003958 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)C4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D21 compound treatment 0.321 0.0104 0.84 0.319 0.0127 1.16 1.4127 0.9877 1392947 Maybridge3_003959 O=S(=O)(NCCc1c[nH]c2ccccc12)c3cccc4nsnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D22 compound treatment 0.344 0.0334 2.69 0.34 0.0338 3.06 4.0702 0.9979 1736799 Maybridge3_003960 CN(C)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccnc4cc(Cl)ccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D23 mock treatment 0.307 -0.00356 -0.29 0.308 0.00175 0.16 -0.0905 -0.2761 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 D24 positive control 0.087 -0.224 -18.0 0.086 -0.22 -19.99 -26.8666 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E01 compound treatment 0.329 0.0184 1.48 0.326 0.0198 1.79 2.3175 0.9956 2077281 Maybridge3_003961 Clc1ccc(cc1)C(=O)N2CCSC2=S 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E02 compound treatment 0.326 0.0154 1.24 0.323 0.0168 1.52 1.9541 0.995 2077282 Maybridge3_003962 CSc1nn(cc1c2noc(n2)c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E03 compound treatment 0.33 0.0194 1.57 0.33 0.0238 2.16 2.6312 0.9876 2077283 Maybridge3_003963 Clc1ccc(NS(=O)(=O)c2cccc3nonc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E04 compound treatment 0.323 0.0124 1.0 0.329 0.0227 2.07 2.1684 0.9448 2077284 Maybridge3_003964 FC(F)(F)c1cccc(Oc2nccnc2c3noc(n3)c4cccs4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E05 compound treatment 0.304 -0.00656 -0.53 0.313 0.00675 0.61 0.0596 0.0736 1319212 Maybridge3_003965 CC(C)C1Oc2c(cccc2NC1=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E06 compound treatment 0.313 0.00244 0.2 0.32 0.0138 1.25 1.0213 0.8084 2077285 Maybridge3_003966 COc1cc(nc2ccc(C#CCO)cc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E07 compound treatment 0.32 0.00944 0.76 0.32 0.0138 1.25 1.4199 0.9717 2077286 Maybridge3_003967 Oc1cc(nc2[nH]nc(c3cccs3)c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E08 compound treatment 0.315 0.00444 0.36 0.312 0.00575 0.52 0.6217 0.9829 2077287 Maybridge3_003968 C(#Cc1ccccc1)c2ccc(s2)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E09 compound treatment 0.331 0.0204 1.65 0.333 0.0267 2.43 2.8807 0.9821 2077288 Maybridge3_003969 CSc1nn2c(cc(nc2c1C#N)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E10 compound treatment 0.344 0.0334 2.69 0.333 0.0267 2.43 3.6209 0.9987 2077289 Maybridge3_003970 FC(F)(F)c1ccc(nc1)N2CCC(CC2)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E11 compound treatment 0.324 0.0134 1.08 0.32 0.0138 1.25 1.6477 0.9975 2077290 Maybridge3_003971 FC(F)(F)c1ccc(SCc2ccc3nonc3c2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E12 compound treatment 0.298 -0.0126 -1.01 0.304 -0.00225 -0.2 -0.8597 -0.8331 2077291 Maybridge3_003972 FC(F)(F)c1ccc2SCC(=O)N(Cc3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E13 compound treatment 0.513 0.202 16.3 0.515 0.209 18.95 24.9256 0.9972 1332456 Maybridge3_003973 Cc1csc(n1)c2sc3ccccc3c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E14 compound treatment 0.315 0.00444 0.36 0.313 0.00675 0.61 0.6859 0.9671 1258662 Maybridge3_003974 CN(C)CC#Cc1ccc(s1)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E15 compound treatment 0.333 0.0224 1.81 0.33 0.0238 2.16 2.802 0.9961 2077292 Maybridge3_003975 COc1c(C)cnc(CO)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E16 compound treatment 0.328 0.0174 1.4 0.323 0.0168 1.52 2.068 0.9992 2077293 Maybridge3_003976 O=C(Nc1ccc2COC(=O)c2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E17 compound treatment 0.324 0.0134 1.08 0.322 0.0158 1.43 1.7761 0.9906 1718090 Maybridge3_003977 N#Cc1ccc(cc1)c2csc(COc3ccc4nonc4c3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E18 compound treatment 0.329 0.0184 1.48 0.331 0.0248 2.25 2.6384 0.9798 2077294 Maybridge3_003978 Brc1ccc(s1)c2ccn(n2)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E19 compound treatment 0.319 0.00844 0.68 0.321 0.0147 1.34 1.4272 0.9506 2077295 Maybridge3_003979 CC(C)(C)c1cc2nc(cc(C#N)n2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E20 compound treatment 0.325 0.0144 1.16 0.329 0.0227 2.07 2.2823 0.9631 1507720 Maybridge3_003980 O=C(Nc1ccccc1)c2ccc(C#Cc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E21 compound treatment 0.327 0.0164 1.32 0.335 0.0288 2.61 2.7813 0.9505 1264652 Maybridge3_003981 Cc1ccc(cc1)C(=O)Nc2ccc3CS(=O)(=O)Cc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E22 compound treatment 0.319 0.00844 0.68 0.317 0.0107 0.98 1.1704 0.9843 1101325 Maybridge3_003982 OC1CN(C1)C(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E23 mock treatment 0.304 -0.00656 -0.53 0.303 -0.00325 -0.3 -0.5823 -0.9621 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 E24 positive control 0.088 -0.223 -17.92 0.089 -0.217 -19.72 -26.6171 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F01 compound treatment 0.327 0.0164 1.32 0.324 0.0177 1.61 2.0753 0.9952 2077296 Maybridge3_003983 CSc1nn(cc1C(=O)Oc2ccc(Cl)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F02 compound treatment 0.33 0.0194 1.57 0.329 0.0227 2.07 2.567 0.9907 2077297 Maybridge3_003984 CC(=O)Nc1c(nn2c(C)cc(nc12)C(F)(F)F)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F03 compound treatment 0.338 0.0274 2.21 0.338 0.0318 2.88 3.6002 0.9914 2077298 Maybridge3_003985 FC(F)(F)c1cc(N2CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F04 compound treatment 0.342 0.0314 2.53 0.338 0.0318 2.88 3.828 0.9979 1662303 Maybridge3_003986 COc1ccc(OC(=O)c2ccc3ncccc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F05 compound treatment 0.336 0.0254 2.05 0.334 0.0278 2.52 3.2296 0.9947 1634093 Maybridge3_003987 O=C(CSc1ccccc1)N2CCC(CC2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F06 compound treatment 0.342 0.0314 2.53 0.337 0.0308 2.79 3.7638 0.9988 2077299 Maybridge3_003988 Nc1nc(cc(n1)C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F07 compound treatment 0.352 0.0414 3.34 0.356 0.0498 4.52 5.5527 0.9889 1420243 Maybridge3_003989 Cc1ccc(NC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F08 compound treatment 0.332 0.0214 1.73 0.34 0.0338 3.06 3.3869 0.9632 2077300 Maybridge3_003990 FC(F)(F)c1ccn(n1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F09 compound treatment 0.324 0.0134 1.08 0.321 0.0147 1.34 1.7119 0.9944 2077301 Maybridge3_003991 CSc1scc(NC(=O)c2ccc(C)cc2)c1S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F10 compound treatment 0.344 0.0334 2.69 0.342 0.0357 3.25 4.1986 0.9957 2077302 Maybridge3_003992 Cn1c(CNC(=O)OC(C)(C)C)nnc1SCc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F11 compound treatment 0.328 0.0174 1.4 0.322 0.0158 1.43 2.0038 1.0 2077303 Maybridge3_003993 CCOC(=O)c1sc(SC)c(c1N)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F12 compound treatment 0.323 0.0124 1.0 0.342 0.0357 3.25 3.0028 0.8842 2077304 Maybridge3_003994 CC(C)NC(=O)CSc1nnc(c2ccc3ncccc3c2)n1CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F13 compound treatment 0.331 0.0204 1.65 0.326 0.0198 1.79 2.4314 0.9991 2077305 Maybridge3_003995 CCOC(=O)Cc1cc(=O)n2nc(cc2[nH]1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F14 compound treatment 0.332 0.0214 1.73 0.331 0.0248 2.25 2.8092 0.9915 1423418 Maybridge3_003996 COC(=O)CSc1ccnc2cc(Cl)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F15 compound treatment 0.329 0.0184 1.48 0.321 0.0147 1.34 1.9966 0.9987 2077306 Maybridge3_003997 FC(F)(F)c1cccc(NC(=O)c2ccc3nonc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F16 compound treatment 0.329 0.0184 1.48 0.331 0.0248 2.25 2.6384 0.9798 2077307 Maybridge3_003998 O=C(Nc1ccc2CS(=O)(=O)Cc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F17 compound treatment 0.327 0.0164 1.32 0.328 0.0217 1.97 2.332 0.9811 2077308 Maybridge3_003999 FC(F)(F)c1cc(n[nH]1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F18 compound treatment 0.324 0.0134 1.08 0.324 0.0177 1.61 1.9044 0.9812 2077309 Maybridge3_004000 Cc1cc(C)c2cc([nH]c2c1)C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F19 compound treatment 0.351 0.0404 3.26 0.346 0.0398 3.61 4.8539 0.9987 1523206 Maybridge3_004001 N#Cc1nccnc1N2CCN(CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F20 compound treatment 0.336 0.0254 2.05 0.34 0.0338 3.06 3.6147 0.9808 1149229 Maybridge3_004002 CCS(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F21 compound treatment 0.324 0.0134 1.08 0.328 0.0217 1.97 2.1612 0.9599 2077310 Maybridge3_004003 CN(C)S(=O)(=O)Nc1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F22 compound treatment 0.348 0.0374 3.01 0.344 0.0377 3.43 4.5547 0.998 1200296 Maybridge3_004004 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)Cc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F23 mock treatment 0.313 0.00244 0.2 0.307 7.5E-4 0.07 0.1869 0.8998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 F24 positive control 0.088 -0.223 -17.92 0.089 -0.217 -19.72 -26.6171 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G01 compound treatment 0.326 0.0154 1.24 0.324 0.0177 1.61 2.0183 0.9918 2077311 Maybridge3_004005 CSc1nnc(SCCS(=O)(=O)c2ccc(Cl)cc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G02 compound treatment 0.326 0.0154 1.24 0.321 0.0147 1.34 1.8258 0.9993 1162460 Maybridge3_004006 OCC#Cc1ccc(s1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G03 compound treatment 0.323 0.0124 1.0 0.325 0.0187 1.7 1.9117 0.968 1636969 Maybridge3_004007 CS(=N)(=O)c1ccc(Oc2cccc(F)c2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G04 compound treatment 0.403 0.0924 7.44 0.398 0.0917 8.33 11.1524 0.9984 2077312 Maybridge3_004008 COC(=O)CSc1cc(nc2c(scc12)C(=O)OC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G05 compound treatment 0.356 0.0454 3.66 0.337 0.0308 2.79 4.5609 0.9911 1130330 Maybridge3_004009 CCOC(=O)CN1C(=O)C(Oc2c(cccc12)C(C)C)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G06 compound treatment 0.323 0.0124 1.0 0.325 0.0187 1.7 1.9117 0.968 1729930 Maybridge3_004010 CCOC(=O)c1cn(Cc2ccccc2)c3cc(C)nn3c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G07 compound treatment 0.325 0.0144 1.16 0.324 0.0177 1.61 1.9614 0.9872 2077313 Maybridge3_004011 CCOC(=O)c1csc(n1)c2ccc3nonc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G08 compound treatment 0.327 0.0164 1.32 0.322 0.0158 1.43 1.9469 0.9993 2077314 Maybridge3_004012 FC(F)(F)C1CCN(CCS(=O)(=O)c2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G09 compound treatment 0.322 0.0114 0.92 0.323 0.0168 1.52 1.7264 0.9712 1726778 Maybridge3_004013 Cc1nc(sc1C(=O)O)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G10 compound treatment 0.323 0.0124 1.0 0.326 0.0198 1.79 1.9759 0.9622 2077315 Maybridge3_004014 CSc1ncc2c(O)ncnc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G11 compound treatment 0.318 0.00744 0.6 0.318 0.0118 1.07 1.1777 0.9628 2077316 Maybridge3_004015 O=S(Cc1ccc2nonc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G12 compound treatment 0.318 0.00744 0.6 0.328 0.0217 1.97 1.8195 0.8819 1382187 Maybridge3_004016 CCOC(=O)c1cncc(C#CC(C)(C)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G13 compound treatment 0.324 0.0134 1.08 0.317 0.0107 0.98 1.4551 0.9987 1638255 Maybridge3_004017 Cc1ccc(cc1)C(=O)NCC2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G14 compound treatment 0.314 0.00344 0.28 0.313 0.00675 0.61 0.629 0.9355 1146518 Maybridge3_004018 NC(=O)CCOC1CCN(CC1)C(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G15 compound treatment 0.327 0.0164 1.32 0.32 0.0138 1.25 1.8185 0.9996 1131426 Maybridge3_004019 CC(C)(C)NC(=O)c1cc(Br)cc2CCOc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G16 compound treatment 0.322 0.0114 0.92 0.323 0.0168 1.52 1.7264 0.9712 1374712 Maybridge3_004020 O=C(Nc1ccc2COC(=O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G17 compound treatment 0.325 0.0144 1.16 0.327 0.0208 1.88 2.1539 0.9731 2077317 Maybridge3_004021 Cc1cc(nc2c(Cl)c(nn12)C3CC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G18 compound treatment 0.327 0.0164 1.32 0.32 0.0138 1.25 1.8185 0.9996 1374157 Maybridge3_004022 O=C(N1CCC(CC1)n2cccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G19 compound treatment 0.329 0.0184 1.48 0.325 0.0187 1.7 2.2533 0.9977 2077318 Maybridge3_004023 Oc1cc(nc2c(OC(F)(F)F)cccc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G20 compound treatment 0.332 0.0214 1.73 0.337 0.0308 2.79 3.1944 0.9733 1689779 Maybridge3_004024 O=C(N1CCOCC1)c2ccc(C#Cc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G21 compound treatment 0.323 0.0124 1.0 0.323 0.0168 1.52 1.7833 0.9795 1702398 Maybridge3_004025 COc1ccc(cc1)S(=O)(=O)Nc2ccc3CS(=O)(=O)Cc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G22 compound treatment 0.318 0.00744 0.6 0.32 0.0138 1.25 1.306 0.9434 1391261 Maybridge3_004026 CCOC(=O)c1c(O)c2cccc(Cl)c2nc1SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G23 mock treatment 0.302 -0.00856 -0.69 0.305 -0.00125 -0.11 -0.5678 -0.8125 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 G24 positive control 0.089 -0.222 -17.84 0.089 -0.217 -19.72 -26.5602 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H01 compound treatment 0.343 0.0324 2.61 0.338 0.0318 2.88 3.8849 0.9988 2077319 Maybridge3_004027 COc1ccc(OC(=O)c2cn(nc2SC)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H02 compound treatment 0.321 0.0104 0.84 0.315 0.00875 0.79 1.1559 0.9996 1405433 Maybridge3_004028 CC(C)N1CCC(CC1)n2nnc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H03 compound treatment 0.334 0.0234 1.89 0.334 0.0278 2.52 3.1157 0.9899 2077320 Maybridge3_004029 FC(F)(F)c1cc(N2CCN(CC2)C(=O)c3ccccc3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H04 compound treatment 0.342 0.0314 2.53 0.337 0.0308 2.79 3.7638 0.9988 1181065 Maybridge3_004030 O=C(N1CCN(CC1)c2ccccc2)c3ccc4ncccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H05 compound treatment 0.316 0.00544 0.44 0.315 0.00875 0.79 0.8712 0.9606 2077321 Maybridge3_004031 O=C(OCC#Cc1ccc(C#N)cc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H06 compound treatment 0.337 0.0264 2.13 0.341 0.0348 3.15 3.7358 0.9817 2077322 Maybridge3_004032 Nc1nc(c2CCc3ccccc3-c2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H07 compound treatment 0.335 0.0244 1.97 0.326 0.0198 1.79 2.6591 0.9989 2077323 Maybridge3_004033 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCC(=O)c3ccc(F)c(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H08 compound treatment 0.323 0.0124 1.0 0.334 0.0278 2.52 2.4893 0.9183 2077324 Maybridge3_004034 FC(F)(F)c1cc(nc2cc(nn12)c3cccs3)c4nccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H09 compound treatment 0.345 0.0344 2.77 0.339 0.0328 2.97 4.063 0.9994 1237588 Maybridge3_004035 CSc1scc(NS(=O)(=O)c2ccc(Cl)cc2)c1S(=O)(=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H10 compound treatment 0.325 0.0144 1.16 0.33 0.0238 2.16 2.3465 0.958 1211183 Maybridge3_004036 COc1cc(NC(=O)c2ccc3snnc3c2)cc(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H11 compound treatment 0.319 0.00844 0.68 0.318 0.0118 1.07 1.2346 0.9763 2077325 Maybridge3_004037 Clc1ccc(cc1)S(=O)(=O)n2ncc(C#N)c2C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H12 compound treatment 0.31 -5.63E-4 -0.05 0.328 0.0217 1.97 1.364 0.6907 1725990 Maybridge3_004038 O=C(NCc1ccco1)c2ccc3snnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H13 compound treatment 0.337 0.0264 2.13 0.343 0.0367 3.34 3.8642 0.9765 1261573 Maybridge3_004039 Clc1ccc(cc1)S(=O)(=O)N(CCC(=O)Nc2ccccc2)Cc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H14 compound treatment 0.323 0.0124 1.0 0.324 0.0177 1.61 1.8475 0.9738 2077326 Maybridge3_004040 COC(=O)c1ccc(Cn2cnc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H15 compound treatment 0.33 0.0194 1.57 0.333 0.0267 2.43 2.8237 0.9774 2077327 Maybridge3_004041 COc1ccc(NC(=O)c2ccc3nonc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H16 compound treatment 0.343 0.0324 2.61 0.344 0.0377 3.43 4.27 0.991 2077328 Maybridge3_004042 CC(=O)N1CCC(CC1)c2nc(no2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H17 compound treatment 0.356 0.0454 3.66 0.361 0.0548 4.97 6.1014 0.9887 2077329 Maybridge3_004043 COc1ccc(cc1OC2CCCC2)c3noc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H18 compound treatment 0.327 0.0164 1.32 0.35 0.0437 3.97 3.7441 0.8944 1331976 Maybridge3_004044 CCc1ccc2[nH]c(cc2c1)C(=O)N(C)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H19 compound treatment 0.322 0.0114 0.92 0.33 0.0238 2.16 2.1757 0.9281 1661316 Maybridge3_004045 Fc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H20 compound treatment 0.344 0.0334 2.69 0.345 0.0388 3.52 4.3911 0.9913 1700688 Maybridge3_004046 CC(C)S(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H21 compound treatment 0.324 0.0134 1.08 0.325 0.0187 1.7 1.9686 0.9761 1535026 Maybridge3_004047 CCOC(=O)Nc1cncc(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H22 compound treatment 0.311 4.37E-4 0.04 0.31 0.00375 0.34 0.2656 0.7761 1199932 Maybridge3_004048 Cc1cc(Nc2ccccc2)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H23 mock treatment 0.308 -0.00256 -0.21 0.305 -0.00125 -0.11 -0.2261 -0.9603 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 H24 positive control 0.092 -0.219 -17.6 0.09 -0.216 -19.63 -26.3252 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I01 compound treatment 0.326 0.0154 1.24 0.329 0.0227 2.07 2.3392 0.9705 2077330 Maybridge3_004049 O/N=C/c1ccc2OCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I02 compound treatment 0.328 0.0174 1.4 0.325 0.0187 1.7 2.1964 0.9954 2077331 Maybridge3_004050 CSc1nn(cc1c2noc(n2)c3cccs3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I03 compound treatment 0.355 0.0444 3.58 0.348 0.0418 3.79 5.21 0.9996 2077332 Maybridge3_004051 Cc1occc1C(=O)C(=C2SCCCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I04 compound treatment 0.321 0.0104 0.84 0.323 0.0168 1.52 1.6694 0.9609 2077333 Maybridge3_004052 O/N=C/C(=O)Nc1ccccc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I05 compound treatment 0.329 0.0184 1.48 0.332 0.0257 2.34 2.7026 0.976 2077334 Maybridge3_004053 CCOC(=O)c1csc(n1)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I06 compound treatment 0.34 0.0294 2.37 0.345 0.0388 3.52 4.1634 0.9816 2077335 Maybridge3_004054 COC(=O)c1sccc1Oc2cc(nc3c(scc23)C(=O)OC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I07 compound treatment 0.308 -0.00256 -0.21 0.307 7.5E-4 0.07 -0.0978 -0.45 1167446 Maybridge3_004055 O=C(Nc1ccccc1)c2csc(n2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I08 compound treatment 0.331 0.0204 1.65 0.327 0.0208 1.88 2.4956 0.9977 2077336 Maybridge3_004056 CC(C)(C)c1cc2nc(cc(SCCO)n2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I09 compound treatment 0.326 0.0154 1.24 0.326 0.0198 1.79 2.1467 0.984 2077337 Maybridge3_004057 CC1(C)Oc2ccc(cc2C=C1)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I10 compound treatment 0.326 0.0154 1.24 0.324 0.0177 1.61 2.0183 0.9918 2077338 Maybridge3_004058 FC(F)(F)c1ccc(nc1)N2CCC(CC2)C(=O)Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I11 compound treatment 0.319 0.00844 0.68 0.302 -0.00425 -0.39 0.2077 0.2658 2077339 Maybridge3_004059 C(SCc1ccc2nonc2c1)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I12 compound treatment 0.318 0.00744 0.6 0.328 0.0217 1.97 1.8195 0.8819 2077340 Maybridge3_004060 O=S(=O)(/C(=C/c1c[nH]cn1)/C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I13 compound treatment 0.329 0.0184 1.48 0.335 0.0288 2.61 2.8952 0.9643 1742782 Maybridge3_004061 CC(C)(C)C(=O)NCC1COc2ccccc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I14 compound treatment 0.324 0.0134 1.08 0.33 0.0238 2.16 2.2895 0.9492 1581992 Maybridge3_004062 COc1ccc(OC(=O)c2cncc(C#Cc3ccccc3)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I15 compound treatment 0.316 0.00544 0.44 0.332 0.0257 2.34 1.9624 0.8252 2077341 Maybridge3_004063 Clc1ccc(CSc2nc3CSCc3c(=O)[nH]2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I16 compound treatment 0.316 0.00544 0.44 0.321 0.0147 1.34 1.2563 0.8919 2077342 Maybridge3_004064 O=C1OCc2ccc(NS(=O)(=O)c3ccccc3)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I17 compound treatment 0.332 0.0214 1.73 0.335 0.0288 2.61 3.066 0.9799 2077343 Maybridge3_004065 Oc1cc(nc2ccc(Br)cc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I18 compound treatment 0.323 0.0124 1.0 0.338 0.0318 2.88 2.7461 0.9 2077344 Maybridge3_004066 Cn1c(SCCS(=O)(=O)c2ccc(F)cc2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I19 compound treatment 0.324 0.0134 1.08 0.329 0.0227 2.07 2.2254 0.9545 2077345 Maybridge3_004067 CC(C)Oc1cc(nc2ccc(C)cc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I20 compound treatment 0.347 0.0364 2.93 0.343 0.0367 3.34 4.4336 0.998 1522065 Maybridge3_004068 O=C(N1CCCCC1)c2ccc(C#Cc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I21 compound treatment 0.331 0.0204 1.65 0.33 0.0238 2.16 2.6881 0.9911 1485285 Maybridge3_004069 NC(=O)C1CCN(CCS(=O)(=O)c2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I22 compound treatment 0.325 0.0144 1.16 0.322 0.0158 1.43 1.833 0.9947 2077346 Maybridge3_004070 O=C(Nc1ccccc1)c2ncc[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I23 mock treatment 0.312 0.00144 0.12 0.309 0.00275 0.25 0.2584 0.939 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 I24 positive control 0.093 -0.218 -17.52 0.091 -0.215 -19.54 -26.204 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J01 compound treatment 0.333 0.0224 1.81 0.332 0.0257 2.34 2.9304 0.9919 1583673 Maybridge3_004071 CSc1nn(cc1C(=O)N2CCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J02 compound treatment 0.334 0.0234 1.89 0.333 0.0267 2.43 3.0515 0.9922 1456490 Maybridge3_004072 OC(=O)C1CN(C1)C(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J03 compound treatment 0.322 0.0114 0.92 0.333 0.0267 2.43 2.3682 0.9119 2077347 Maybridge3_004073 C(#Cc1ccc(cc1)c2ccn[nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J04 compound treatment 0.328 0.0174 1.4 0.328 0.0217 1.97 2.3889 0.9861 1541332 Maybridge3_004074 O=C(N1CCOCC1)c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J05 compound treatment 0.338 0.0274 2.21 0.334 0.0278 2.52 3.3434 0.9979 2077348 Maybridge3_004075 CCOC(=O)Cc1c(C(=O)OCC)c(C)cn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J06 compound treatment 0.335 0.0244 1.97 0.331 0.0248 2.25 2.9801 0.9978 1477926 Maybridge3_004076 Cn1c(SCC(=O)NCc2ccccc2)nnc1c3ccc4ncccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J07 compound treatment 0.329 0.0184 1.48 0.32 0.0138 1.25 1.9324 0.9963 2077349 Maybridge3_004077 C/C(=N\O)/c1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J08 compound treatment 0.329 0.0184 1.48 0.326 0.0198 1.79 2.3175 0.9956 2077350 Maybridge3_004078 OCCN1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J09 compound treatment 0.326 0.0154 1.24 0.322 0.0158 1.43 1.8899 0.9976 2077351 Maybridge3_004079 COc1ccc(/C=N/O)cc1OC2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J10 compound treatment 0.334 0.0234 1.89 0.334 0.0278 2.52 3.1157 0.9899 2077352 Maybridge3_004080 COC(=O)c1ccc(CSc2nnc(c3ccc4ncccc4c3)n2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J11 compound treatment 0.324 0.0134 1.08 0.324 0.0177 1.61 1.9044 0.9812 1118471 Maybridge3_004081 Clc1ccc(cc1)C(=O)n2ncc(C#N)c2C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J12 compound treatment 0.332 0.0214 1.73 0.332 0.0257 2.34 2.8734 0.9889 2077353 Maybridge3_004082 OC1CCN(CC1)c2cc(nc3cc(Cl)cc(Cl)c23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J13 compound treatment 0.319 0.00844 0.68 0.312 0.00575 0.52 0.8495 0.9915 1435746 Maybridge3_004083 CCOC(=O)Cc1cc(=O)n2nc(C)cc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J14 compound treatment 0.321 0.0104 0.84 0.321 0.0147 1.34 1.541 0.9748 2077354 Maybridge3_004084 CC(C)n1c(nc2cc(ccc12)C(=O)NCc3ccncc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J15 compound treatment 0.326 0.0154 1.24 0.324 0.0177 1.61 2.0183 0.9918 1545156 Maybridge3_004085 Clc1ccc(NC(=O)c2ccc3nonc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J16 compound treatment 0.317 0.00644 0.52 0.319 0.0127 1.16 1.1849 0.9344 2077355 Maybridge3_004086 C1CCN(CC1)c2noc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J17 compound treatment 0.322 0.0114 0.92 0.319 0.0127 1.16 1.4696 0.9936 2077356 Maybridge3_004087 Cn1c(SCc2ccccc2)nnc1c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J18 compound treatment 0.319 0.00844 0.68 0.336 0.0297 2.7 2.3899 0.8583 2077357 Maybridge3_004088 CN(C(=O)c1cc2c(C)cc(C)cc2[nH]1)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J19 compound treatment 0.326 0.0154 1.24 0.329 0.0227 2.07 2.3392 0.9705 2077358 Maybridge3_004089 FC(F)(F)c1cc(N2CCCC2)c3cccc(Cl)c3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J20 compound treatment 0.325 0.0144 1.16 0.326 0.0198 1.79 2.0897 0.978 1547868 Maybridge3_004090 Clc1ccc2c(Nc3ccc4OCOc4c3)ccnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J21 compound treatment 0.318 0.00744 0.6 0.32 0.0138 1.25 1.306 0.9434 1436487 Maybridge3_004091 O=S(=O)(N1CCc2ccccc12)c3cccc4nsnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J22 compound treatment 0.31 -5.63E-4 -0.05 0.309 0.00275 0.25 0.1445 0.5695 1712208 Maybridge3_004092 Cc1cc(Nc2ccc(C)c(F)c2)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J23 mock treatment 0.307 -0.00356 -0.29 0.303 -0.00325 -0.3 -0.4115 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 J24 positive control 0.093 -0.218 -17.52 0.091 -0.215 -19.54 -26.204 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K01 compound treatment 0.332 0.0214 1.73 0.331 0.0248 2.25 2.8092 0.9915 2077359 Maybridge3_004093 N/C(=N/O)/C1COc2ccccc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K02 compound treatment 0.327 0.0164 1.32 0.322 0.0158 1.43 1.9469 0.9993 2077360 Maybridge3_004094 CS(=O)(=O)NCCSc1cc(nc2ccccc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K03 compound treatment 0.338 0.0274 2.21 0.333 0.0267 2.43 3.2793 0.9989 1286819 Maybridge3_004095 O=C(Sc1cccs1)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K04 compound treatment 0.389 0.0784 6.32 0.379 0.0727 6.6 9.1358 0.9998 2077361 Maybridge3_004096 COC(=O)c1scc2c(Sc3nccn3C)cc(nc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K05 compound treatment 0.331 0.0204 1.65 0.325 0.0187 1.7 2.3672 0.9999 1368806 Maybridge3_004097 Clc1ccccc1c2nc(no2)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K06 compound treatment 0.324 0.0134 1.08 0.324 0.0177 1.61 1.9044 0.9812 1522513 Maybridge3_004098 Cc1[nH]c2ccccc2c1SCc3nnc(SCC(=O)Nc4ccccc4)n3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K07 compound treatment 0.324 0.0134 1.08 0.319 0.0127 1.16 1.5835 0.9994 1339013 Maybridge3_004099 CN(C)C(=O)c1csc(n1)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K08 compound treatment 0.331 0.0204 1.65 0.325 0.0187 1.7 2.3672 0.9999 2077362 Maybridge3_004100 CCOC(=O)c1ccc(OCC#Cc2ccc(cn2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K09 compound treatment 0.322 0.0114 0.92 0.317 0.0107 0.98 1.3413 0.9996 1146145 Maybridge3_004101 O=C(Nc1ccccc1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K10 compound treatment 0.32 0.00944 0.76 0.323 0.0168 1.52 1.6125 0.9486 1555938 Maybridge3_004102 O=S1(=O)CC(N2CCCCC2)c3ccccc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K11 compound treatment 0.33 0.0194 1.57 0.33 0.0238 2.16 2.6312 0.9876 2077363 Maybridge3_004103 CN(C(=O)c1ccc2OCCc2c1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K12 compound treatment 0.321 0.0104 0.84 0.33 0.0238 2.16 2.1187 0.9157 2077364 Maybridge3_004104 CC(C)S(=O)(=O)/C(=C/c1c[nH]cn1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K13 compound treatment 0.311 4.37E-4 0.04 0.316 0.00975 0.89 0.6507 0.7347 2077365 Maybridge3_004105 Nc1ccccc1SCc2ccc3nonc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K14 compound treatment 0.32 0.00944 0.76 0.324 0.0177 1.61 1.6767 0.9412 1460370 Maybridge3_004106 C(#Cc1cncc(c1)c2nc(no2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K15 compound treatment 0.427 0.116 9.38 0.434 0.128 11.6 14.8297 0.9944 2077366 Maybridge3_004107 Cn1cc(cc1/C=C(\C#N)/S(=O)(=O)c2cccs2)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K16 compound treatment 0.339 0.0284 2.29 0.345 0.0388 3.52 4.1064 0.9784 2077367 Maybridge3_004108 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3cncc(C#Cc4ccccc4)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K17 compound treatment 0.324 0.0134 1.08 0.328 0.0217 1.97 2.1612 0.9599 2077368 Maybridge3_004109 Cc1cc(C)n2nc(c(Cl)c2n1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K18 compound treatment 0.326 0.0154 1.24 0.331 0.0248 2.25 2.4676 0.9611 2077369 Maybridge3_004110 FC(F)(F)c1ccc(nc1)N2CCC(CC2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K19 compound treatment 0.321 0.0104 0.84 0.323 0.0168 1.52 1.6694 0.9609 2077370 Maybridge3_004111 Cn1c(Sc2cccs2)nc(C#N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K20 compound treatment 0.336 0.0254 2.05 0.342 0.0357 3.25 3.743 0.9754 1197251 Maybridge3_004112 O=C(N1CCCC1)c2ccc(C#Cc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K21 compound treatment 0.326 0.0154 1.24 0.324 0.0177 1.61 2.0183 0.9918 2077371 Maybridge3_004113 OC(=O)CSc1cc(nc2ccccc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K22 compound treatment 0.321 0.0104 0.84 0.319 0.0127 1.16 1.4127 0.9877 1060162 Maybridge3_004114 O=C1CC2CCCC(C1)N2Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K23 mock treatment 0.319 0.00844 0.68 0.303 -0.00325 -0.3 0.2718 0.367 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 K24 positive control 0.092 -0.219 -17.6 0.092 -0.214 -19.45 -26.1968 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L01 compound treatment 0.348 0.0374 3.01 0.344 0.0377 3.43 4.5547 0.998 2077372 Maybridge3_004115 COC(=O)c1c(C)[nH]c(C)c1/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L02 compound treatment 0.328 0.0174 1.4 0.325 0.0187 1.7 2.1964 0.9954 2077373 Maybridge3_004116 COC(=O)c1ccccc1NC(=O)/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L03 compound treatment 0.321 0.0104 0.84 0.318 0.0118 1.07 1.3485 0.993 1421413 Maybridge3_004117 COC(=O)C(Cc1csc2ccc(Cl)cc12)NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L04 compound treatment 0.328 0.0174 1.4 0.327 0.0208 1.88 2.3247 0.9895 1389033 Maybridge3_004118 COC(=O)c1sccc1NC(=O)c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L05 compound treatment 0.334 0.0234 1.89 0.326 0.0198 1.79 2.6022 0.9997 2077374 Maybridge3_004119 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L06 compound treatment 0.329 0.0184 1.48 0.326 0.0198 1.79 2.3175 0.9956 2077375 Maybridge3_004120 COC(=O)c1ccc2n(nnc2c1)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L07 compound treatment 0.323 0.0124 1.0 0.323 0.0168 1.52 1.7833 0.9795 2077376 Maybridge3_004121 Nc1cc(n[nH]1)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L08 compound treatment 0.318 0.00744 0.6 0.328 0.0217 1.97 1.8195 0.8819 1207721 Maybridge3_004122 Cn1nnnc1SCC(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L09 compound treatment 0.364 0.0534 4.3 0.363 0.0568 5.15 6.6853 0.996 2077377 Maybridge3_004123 C/C(=N\O)/c1ccc(C#Cc2ccccc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L10 compound treatment 0.333 0.0224 1.81 0.326 0.0198 1.79 2.5453 1.0 2077378 Maybridge3_004124 CSc1nnc(c2ccc3ncccc3c2)n1CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L11 compound treatment 0.321 0.0104 0.84 0.324 0.0177 1.61 1.7336 0.954 2077379 Maybridge3_004125 O=C(c1cccs1)n2ncc(C#N)c2C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L12 compound treatment 0.336 0.0254 2.05 0.34 0.0338 3.06 3.6147 0.9808 2077380 Maybridge3_004126 FC(F)(F)c1cc(N2CCC(=O)CC2)c3c(Cl)cc(Cl)cc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L13 compound treatment 0.333 0.0224 1.81 0.332 0.0257 2.34 2.9304 0.9919 1174104 Maybridge3_004127 CCOC(=O)Cc1cc(=O)n2nc(cc2[nH]1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L14 compound treatment 0.338 0.0274 2.21 0.34 0.0338 3.06 3.7286 0.9871 2077381 Maybridge3_004128 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCCCC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L15 compound treatment 0.335 0.0244 1.97 0.319 0.0127 1.16 2.2099 0.968 1556737 Maybridge3_004129 Clc1ccc(OC(=O)c2ccc3nonc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L16 compound treatment 0.322 0.0114 0.92 0.323 0.0168 1.52 1.7264 0.9712 1225885 Maybridge3_004130 COc1ccc2c(CC(=O)O)coc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L17 compound treatment 0.324 0.0134 1.08 0.321 0.0147 1.34 1.7119 0.9944 1128713 Maybridge3_004131 CSc1nc(N)nc(n1)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L18 compound treatment 0.314 0.00344 0.28 0.308 0.00175 0.16 0.3081 0.9652 1364620 Maybridge3_004132 O=C(NCc1ccc(s1)S(=O)(=O)NCCc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L19 compound treatment 0.327 0.0164 1.32 0.322 0.0158 1.43 1.9469 0.9993 1329219 Maybridge3_004133 Clc1ccc(cc1)S(=O)(=O)CCN2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L20 compound treatment 0.358 0.0474 3.82 0.364 0.0578 5.24 6.4078 0.9879 1549522 Maybridge3_004134 Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L21 compound treatment 0.32 0.00944 0.76 0.315 0.00875 0.79 1.099 0.9998 1288040 Maybridge3_004135 N#CC1(CCN(Cc2ccccc2)CC1)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L22 compound treatment 0.32 0.00944 0.76 0.316 0.00975 0.89 1.1632 0.9971 1682067 Maybridge3_004136 O=C(NCc1ccc(s1)S(=O)(=O)NC2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L23 mock treatment 0.314 0.00344 0.28 0.307 7.5E-4 0.07 0.2439 0.8555 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 L24 positive control 0.092 -0.219 -17.6 0.092 -0.214 -19.45 -26.1968 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M01 compound treatment 0.373 0.0624 5.03 0.369 0.0628 5.7 7.5829 0.9981 2077382 Maybridge3_004137 CSC(=C(C#N)C(=O)c1ccoc1C)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M02 compound treatment 0.316 0.00544 0.44 0.312 0.00575 0.52 0.6787 0.9962 2077383 Maybridge3_004138 O=C(OCC#Cc1ccc(s1)c2ccccn2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M03 compound treatment 0.329 0.0184 1.48 0.319 0.0127 1.16 1.8682 0.9924 1134608 Maybridge3_004139 O=C(Nc1cc(n[nH]1)c2ccccc2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M04 compound treatment 0.32 0.00944 0.76 0.316 0.00975 0.89 1.1632 0.9971 2077384 Maybridge3_004140 FC(F)(F)c1ccc(Oc2ccc(Br)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M05 compound treatment 0.326 0.0154 1.24 0.319 0.0127 1.16 1.6974 0.9994 1601097 Maybridge3_004141 COc1ccc(NS(=O)(=O)c2cn(C)cn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M06 compound treatment 0.325 0.0144 1.16 0.325 0.0187 1.7 2.0256 0.9827 1644493 Maybridge3_004142 Clc1ccc(Cn2ccnc2COC(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M07 compound treatment 0.315 0.00444 0.36 0.311 0.00475 0.43 0.5576 0.9956 1286518 Maybridge3_004143 O=C(NCc1ccco1)c2csc(n2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M08 compound treatment 0.326 0.0154 1.24 0.32 0.0138 1.25 1.7616 1.0 2077385 Maybridge3_004144 CC(C)(O)C#Cc1ccc(CO)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M09 compound treatment 0.32 0.00944 0.76 0.316 0.00975 0.89 1.1632 0.9971 2077386 Maybridge3_004145 CNC(=O)c1ccc2OCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M10 compound treatment 0.328 0.0174 1.4 0.316 0.00975 0.89 1.6187 0.9752 1677679 Maybridge3_004146 Clc1ccc(s1)S(=O)(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M11 compound treatment 0.134 -0.177 -14.22 0.134 -0.172 -15.64 -21.1095 -0.9989 1430746 Maybridge3_004147 CN(C)CC1COc2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M12 compound treatment 0.32 0.00944 0.76 0.31 0.00375 0.34 0.7781 0.9344 2077387 Maybridge3_004148 Clc1ccc(cc1)S(=O)(=O)/C(=C/c2c[nH]cn2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M13 compound treatment 0.334 0.0234 1.89 0.328 0.0217 1.97 2.7306 0.9997 1167106 Maybridge3_004149 Brc1cc2CCOc2c(c1)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M14 compound treatment 0.317 0.00644 0.52 0.319 0.0127 1.16 1.1849 0.9344 2077388 Maybridge3_004150 CN(C)CC#Cc1cncc(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M15 compound treatment 0.321 0.0104 0.84 0.322 0.0158 1.43 1.6052 0.9679 1276171 Maybridge3_004151 N#Cc1ccc(OCc2ccc3nonc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M16 compound treatment 0.303 -0.00756 -0.61 0.295 -0.0113 -1.02 -1.1527 -0.9695 2077389 Maybridge3_004152 O=C(Sc1cccs1)c2cncc(C#Cc3ccccc3)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M17 compound treatment 0.324 0.0134 1.08 0.327 0.0208 1.88 2.097 0.9654 2077390 Maybridge3_004153 O=C(Sc1ccccc1)c2ccc3ncsc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M18 compound treatment 0.316 0.00544 0.44 0.319 0.0127 1.16 1.128 0.9116 2077391 Maybridge3_004154 Fc1ccc(cc1)S(=O)(=O)CCSc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M19 compound treatment 0.327 0.0164 1.32 0.325 0.0187 1.7 2.1394 0.9923 2077392 Maybridge3_004155 Cn1c(CC2Sc3ccccc3NC2=O)nnc1SCC(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M20 compound treatment 0.326 0.0154 1.24 0.323 0.0168 1.52 1.9541 0.995 2077393 Maybridge3_004156 COC(=O)CSCC1=CS(=O)(=O)c2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M21 compound treatment 0.324 0.0134 1.08 0.323 0.0168 1.52 1.8402 0.9861 1387055 Maybridge3_004157 Cc1ncn2cc([nH]c(=O)c12)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M22 compound treatment 0.321 0.0104 0.84 0.315 0.00875 0.79 1.1559 0.9996 1682804 Maybridge3_004158 ON=C1CC2CCCC(C1)N2Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M23 mock treatment 0.306 -0.00456 -0.37 0.302 -0.00425 -0.39 -0.5326 -0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 M24 positive control 0.093 -0.218 -17.52 0.093 -0.213 -19.36 -26.0757 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N01 compound treatment 0.334 0.0234 1.89 0.332 0.0257 2.34 2.9873 0.9944 2077394 Maybridge3_004159 CS(=O)(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N02 compound treatment 0.331 0.0204 1.65 0.326 0.0198 1.79 2.4314 0.9991 1276474 Maybridge3_004160 O=C(Nc1ccccc1)c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N03 compound treatment 0.324 0.0134 1.08 0.325 0.0187 1.7 1.9686 0.9761 2077395 Maybridge3_004161 CC(=O)n1ccc(n1)c2ccc(C#Cc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N04 compound treatment 0.333 0.0224 1.81 0.328 0.0217 1.97 2.6736 0.999 1515408 Maybridge3_004162 Clc1ccc(cc1)C(=O)N2CCC(CC2)n3nnc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N05 compound treatment 0.322 0.0114 0.92 0.321 0.0147 1.34 1.598 0.9833 2077396 Maybridge3_004163 c1ccc(cc1)c2cc3ccccc3nn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N06 compound treatment 0.338 0.0274 2.21 0.338 0.0318 2.88 3.6002 0.9914 1203539 Maybridge3_004164 COc1ccc(cc1OC)C(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N07 compound treatment 0.323 0.0124 1.0 0.323 0.0168 1.52 1.7833 0.9795 1329343 Maybridge3_004165 CC(=O)NC(=O)c1cnn(c1N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N08 compound treatment 0.323 0.0124 1.0 0.326 0.0198 1.79 1.9759 0.9622 1485969 Maybridge3_004166 Cn1ccnc1SCC(=O)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N09 compound treatment 0.337 0.0264 2.13 0.341 0.0348 3.15 3.7358 0.9817 2077397 Maybridge3_004167 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)C2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N10 compound treatment 0.328 0.0174 1.4 0.326 0.0198 1.79 2.2606 0.9927 2077398 Maybridge3_004168 Cn1c(SCC#N)nnc1c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N11 compound treatment 0.319 0.00844 0.68 0.321 0.0147 1.34 1.4272 0.9506 1461212 Maybridge3_004169 CSc1sc(C(=O)O)c(C)c1C(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N12 compound treatment 0.33 0.0194 1.57 0.331 0.0248 2.25 2.6954 0.9844 2077399 Maybridge3_004170 Fc1ccc2nc(cc(N3CCOCC3)c2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N13 compound treatment 0.332 0.0214 1.73 0.331 0.0248 2.25 2.8092 0.9915 2077400 Maybridge3_004171 FC(F)(F)c1cc(nc2cc(nn12)c3ccccc3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N14 compound treatment 0.329 0.0184 1.48 0.333 0.0267 2.43 2.7668 0.9721 2077401 Maybridge3_004172 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCC(O)CC3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N15 compound treatment 0.32 0.00944 0.76 0.323 0.0168 1.52 1.6125 0.9486 1710980 Maybridge3_004173 COc1ccc(OC(=O)c2ccc3nonc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N16 compound treatment 0.329 0.0184 1.48 0.334 0.0278 2.52 2.831 0.9682 2077402 Maybridge3_004174 CCc1ccc2[nH]c(cc2c1)C(=O)NCCN3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N17 compound treatment 0.322 0.0114 0.92 0.328 0.0217 1.97 2.0473 0.9397 1579669 Maybridge3_004175 Nc1nc(ncc1C#N)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N18 compound treatment 0.335 0.0244 1.97 0.34 0.0338 3.06 3.5577 0.9771 1418287 Maybridge3_004176 Clc1ccc2c(Nc3ccccc3)ccnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N19 compound treatment 0.316 0.00544 0.44 0.315 0.00875 0.79 0.8712 0.9606 1622980 Maybridge3_004177 Brc1ccc(s1)S(=O)(=O)N2CCN(CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N20 compound treatment 0.344 0.0334 2.69 0.349 0.0428 3.88 4.6479 0.9841 1739946 Maybridge3_004178 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N21 compound treatment 0.331 0.0204 1.65 0.339 0.0328 2.97 3.2658 0.9611 2077403 Maybridge3_004179 Cc1cc(Nc2cc(nc3c(Cl)cccc23)C(F)(F)F)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N22 compound treatment 0.336 0.0254 2.05 0.332 0.0257 2.34 3.1012 0.9978 1374568 Maybridge3_004180 CCC(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N23 mock treatment 0.312 0.00144 0.12 0.309 0.00275 0.25 0.2584 0.939 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 N24 positive control 0.094 -0.217 -17.44 0.092 -0.214 -19.45 -26.0829 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O01 compound treatment 0.388 0.0774 6.24 0.384 0.0778 7.06 9.3997 0.9981 2077404 Maybridge3_004181 O=S(=O)(Nc1cccc2nsnc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O02 compound treatment 0.375 0.0644 5.19 0.393 0.0867 7.87 9.2372 0.9795 2077405 Maybridge3_004182 Clc1cccc(NC(=O)OCC#Cc2ccc(s2)c3ccccn3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O03 compound treatment 0.327 0.0164 1.32 0.323 0.0168 1.52 2.0111 0.9976 1586200 Maybridge3_004183 CC(C)(C)c1cc(NC(=O)C2COc3ccccc3O2)[nH]n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O04 compound treatment 0.394 0.0834 6.72 0.389 0.0828 7.51 10.0623 0.9985 2077406 Maybridge3_004184 COC(=O)c1scc2c(cc(nc12)C(F)(F)F)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O05 compound treatment 0.329 0.0184 1.48 0.325 0.0187 1.7 2.2533 0.9977 1200852 Maybridge3_004185 OC(=O)c1csc(n1)C2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O06 compound treatment 0.324 0.0134 1.08 0.322 0.0158 1.43 1.7761 0.9906 1252194 Maybridge3_004186 Clc1ccc(Cn2ccnc2COC(=O)Nc3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O07 compound treatment 0.324 0.0134 1.08 0.328 0.0217 1.97 2.1612 0.9599 1603073 Maybridge3_004187 O=C(SCc1ccco1)c2csc(n2)C3COc4ccccc4O3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O08 compound treatment 0.326 0.0154 1.24 0.327 0.0208 1.88 2.2109 0.9797 1365631 Maybridge3_004188 O=S1(=O)CC(Sc2ccccc2)c3ccccc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O09 compound treatment 0.331 0.0204 1.65 0.33 0.0238 2.16 2.6881 0.9911 1337081 Maybridge3_004189 CC(C)(C)NC(=O)c1ccc2OCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O10 compound treatment 0.333 0.0224 1.81 0.332 0.0257 2.34 2.9304 0.9919 1676570 Maybridge3_004190 CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O11 compound treatment 0.329 0.0184 1.48 0.331 0.0248 2.25 2.6384 0.9798 2077407 Maybridge3_004191 CSc1ncc(c2nnc(SCc3ccccc3)n2C)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O12 compound treatment 0.357 0.0464 3.74 0.349 0.0428 3.88 5.3881 0.9998 2077408 Maybridge3_004192 CCOC(=O)c1cncc(C#CCOC(=O)Nc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O13 compound treatment 0.327 0.0164 1.32 0.323 0.0168 1.52 2.0111 0.9976 2077409 Maybridge3_004193 CN(C)C(=O)c1cc(Br)cc2CCOc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O14 compound treatment 0.325 0.0144 1.16 0.321 0.0147 1.34 1.7688 0.9975 2077410 Maybridge3_004194 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O15 compound treatment 0.335 0.0244 1.97 0.333 0.0267 2.43 3.1084 0.9946 1347374 Maybridge3_004195 Cc1c(ncn1Cc2ccc(Cl)cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O16 compound treatment 0.342 0.0314 2.53 0.338 0.0318 2.88 3.828 0.9979 2077411 Maybridge3_004196 Clc1ccc(cc1)S(=O)(=O)/C(=C/NC2CCN(Cc3ccccc3)CC2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O17 compound treatment 0.331 0.0204 1.65 0.326 0.0198 1.79 2.4314 0.9991 2077412 Maybridge3_004197 CN(C)C(=O)c1ccc2ncsc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O18 compound treatment 0.328 0.0174 1.4 0.329 0.0227 2.07 2.4531 0.9823 1389063 Maybridge3_004198 NC(=O)C1CCN(CCO)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O19 compound treatment 0.322 0.0114 0.92 0.313 0.00675 0.61 1.0845 0.9804 2077413 Maybridge3_004199 CN(C)CCOc1cc(nc2ccc(C)cc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O20 compound treatment 0.322 0.0114 0.92 0.323 0.0168 1.52 1.7264 0.9712 2077414 Maybridge3_004200 Clc1ccc2c(c1)C(=CS2(=O)=O)CSc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O21 compound treatment 0.339 0.0284 2.29 0.332 0.0257 2.34 3.272 0.9999 2077415 Maybridge3_004201 CC(C)NC(=O)CSc1nnc(CSc2cc(nc3ccccc23)C(F)(F)F)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O22 compound treatment 0.328 0.0174 1.4 0.321 0.0147 1.34 1.9396 0.9997 2077416 Maybridge3_004202 CSc1nn(cc1C(=O)Nc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O23 mock treatment 0.323 0.0124 1.0 0.316 0.00975 0.89 1.334 0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 O24 positive control 0.093 -0.218 -17.52 0.093 -0.213 -19.36 -26.0757 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P01 compound treatment 0.328 0.0174 1.4 0.329 0.0227 2.07 2.4531 0.9823 1584127 Maybridge3_004203 CCOC(=O)C1=C(NC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P02 compound treatment 0.329 0.0184 1.48 0.327 0.0208 1.88 2.3817 0.9931 1515716 Maybridge3_004204 COc1ccc(NC(=O)c2ccc3ncccc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P03 compound treatment 0.324 0.0134 1.08 0.321 0.0147 1.34 1.7119 0.9944 2077417 Maybridge3_004205 FC(F)(F)Oc1ccc(CC2SC(=N)NC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P04 compound treatment 0.342 0.0314 2.53 0.343 0.0367 3.34 4.1489 0.9907 2077418 Maybridge3_004206 COc1ccc(cc1)c2cc(n3nccc3n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P05 compound treatment 0.359 0.0484 3.9 0.359 0.0527 4.79 6.1438 0.9948 1126864 Maybridge3_004207 OC(=O)c1c(nnc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P06 compound treatment 0.34 0.0294 2.37 0.342 0.0357 3.25 3.9708 0.9881 1447911 Maybridge3_004208 O=C(NC1Cc2ccccc2C1)c3ccc4nonc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P07 compound treatment 0.323 0.0124 1.0 0.322 0.0158 1.43 1.7191 0.9848 2077419 Maybridge3_004209 CCCN(Cc1ccco1)S(=O)(=O)c2ccc(OC)c(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P08 compound treatment 0.325 0.0144 1.16 0.323 0.0168 1.52 1.8972 0.9912 1328406 Maybridge3_004210 O=C(CSC1=NCCS1)NC2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P09 compound treatment 0.323 0.0124 1.0 0.321 0.0147 1.34 1.6549 0.9898 2077420 Maybridge3_004211 COc1ccc(cc1OC2CCCC2)S(=O)(=O)NCc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P10 compound treatment 0.327 0.0164 1.32 0.325 0.0187 1.7 2.1394 0.9923 2077421 Maybridge3_004212 C=CCn1c(SCC#N)nnc1c2ccc3ncccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P11 compound treatment 0.324 0.0134 1.08 0.325 0.0187 1.7 1.9686 0.9761 1510724 Maybridge3_004213 OC(=O)CCN(Cc1ccco1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P12 compound treatment 0.335 0.0244 1.97 0.334 0.0278 2.52 3.1726 0.9925 2077422 Maybridge3_004214 CCOC(=O)c1ccc2nc(cc(N3CCN(C)CC3)c2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P13 compound treatment 0.333 0.0224 1.81 0.327 0.0208 1.88 2.6095 0.9998 2077423 Maybridge3_004215 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P14 compound treatment 0.328 0.0174 1.4 0.326 0.0198 1.79 2.2606 0.9927 1372489 Maybridge3_004216 CN1CCN(CC1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P15 compound treatment 0.319 0.00844 0.68 0.317 0.0107 0.98 1.1704 0.9843 2077424 Maybridge3_004217 FC(F)(F)c1cccc(OC(=O)c2ccc3nonc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P16 compound treatment 0.323 0.0124 1.0 0.325 0.0187 1.7 1.9117 0.968 1348162 Maybridge3_004218 Cc1cc(C)c2cc([nH]c2c1)C(=O)NCCN3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P17 compound treatment 0.338 0.0274 2.21 0.34 0.0338 3.06 3.7286 0.9871 2077425 Maybridge3_004219 FC(F)(F)c1cc(no1)c2ccc(s2)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P18 compound treatment 0.34 0.0294 2.37 0.339 0.0328 2.97 3.7783 0.9937 1553305 Maybridge3_004220 Clc1ccc2c(ccnc2c1)N3CCN(CC3)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P19 compound treatment 0.333 0.0224 1.81 0.327 0.0208 1.88 2.6095 0.9998 2077426 Maybridge3_004221 CCOC(=O)C1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P20 compound treatment 0.332 0.0214 1.73 0.327 0.0208 1.88 2.5525 0.9991 1155426 Maybridge3_004222 CC(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P21 compound treatment 0.328 0.0174 1.4 0.326 0.0198 1.79 2.2606 0.9927 1324782 Maybridge3_004223 COc1ccc(cc1OC(C)C)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P22 compound treatment 0.34 0.0294 2.37 0.339 0.0328 2.97 3.7783 0.9937 2077427 Maybridge3_004224 FC(F)(F)c1cc(N2CCN(CC2)C(=O)Cc3ccccc3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P23 mock treatment 0.312 0.00144 0.12 0.311 0.00475 0.43 0.3867 0.8663 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1442 P24 positive control 0.095 -0.216 -17.36 0.095 -0.211 -19.18 -25.8334 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A01 compound treatment 0.313 0.00238 0.19 0.317 -0.00194 -0.18 0.0109 0.0419 2077428 Maybridge3_004225 FC(F)(F)c1cc(N2CCN(CC2)C(=O)C3CCCCC3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A02 compound treatment 0.312 0.00138 0.11 0.318 -9.37E-4 -0.09 0.0181 0.1298 2077429 Maybridge3_004226 Clc1ccccc1NC(=O)CSc2nccc(n2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A03 compound treatment 0.321 0.0104 0.84 0.324 0.00506 0.46 0.9157 0.9604 2077430 Maybridge3_004227 CCOC(=O)c1sc2ncccc2c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A04 compound treatment 0.309 -0.00162 -0.13 0.315 -0.00394 -0.36 -0.3453 -0.9071 2077431 Maybridge3_004228 CSc1nccc(n1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A05 compound treatment 0.308 -0.00262 -0.21 0.323 0.00406 0.37 0.1113 0.2618 1631069 Maybridge3_004229 Cc1ccc(Nc2nnns2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A06 compound treatment 0.291 -0.0196 -1.58 0.295 -0.0239 -2.17 -2.6539 -0.9878 1237347 Maybridge3_004230 O=C(CCNc1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A07 compound treatment 0.308 -0.00262 -0.21 0.309 -0.00994 -0.9 -0.7873 -0.8498 1063282 Maybridge3_004231 Cc1cc(cc(O)n1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A08 compound treatment 0.305 -0.00562 -0.45 0.311 -0.00794 -0.72 -0.8298 -0.975 1404523 Maybridge3_004232 Clc1ccccc1c2snc(N3CCOCC3)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A09 compound treatment 0.299 -0.0116 -0.94 0.308 -0.0109 -0.99 -1.364 -0.9996 2077432 Maybridge3_004233 Cc1ccccc1C(=O)Cc2ccc(cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A10 compound treatment 0.304 -0.00662 -0.53 0.309 -0.00994 -0.9 -1.0151 -0.9686 2077433 Maybridge3_004234 c1nc(c2csc(n2)c3ccncc3)n(n1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A11 compound treatment 0.304 -0.00662 -0.53 0.312 -0.00694 -0.63 -0.8225 -0.9966 2077434 Maybridge3_004235 COc1cccc2onc(N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A12 compound treatment 0.305 -0.00562 -0.45 0.313 -0.00594 -0.54 -0.7014 -0.9963 1208433 Maybridge3_004236 CC(C)(C)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A13 compound treatment 0.305 -0.00562 -0.45 0.315 -0.00394 -0.36 -0.573 -0.9931 2077435 Maybridge3_004237 Cc1nc(Br)sc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A14 compound treatment 0.296 -0.0146 -1.18 0.313 -0.00594 -0.54 -1.2139 -0.9372 2077436 Maybridge3_004238 Cc1ccc(SCC(=O)Nc2ccc(C#N)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A15 compound treatment 0.305 -0.00562 -0.45 0.316 -0.00294 -0.27 -0.5088 -0.9681 1172342 Maybridge3_004239 Cc1nc2ccc(NC(=O)c3ccccc3Cl)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A16 compound treatment 0.306 -0.00462 -0.37 0.314 -0.00494 -0.45 -0.5803 -0.9958 1299835 Maybridge3_004240 C(N1CCc2ccccc12)n3nnc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A17 compound treatment 0.304 -0.00662 -0.53 0.316 -0.00294 -0.27 -0.5658 -0.9486 2077437 Maybridge3_004241 CN(C)C(=O)Cc1sc2ccccc2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A18 compound treatment 0.303 -0.00762 -0.61 0.314 -0.00494 -0.45 -0.7511 -0.988 2077438 Maybridge3_004242 FC(F)(F)Oc1ccc(NC(=O)CSc2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A19 compound treatment 0.307 -0.00362 -0.29 0.316 -0.00294 -0.27 -0.395 -0.999 1343191 Maybridge3_004243 Cc1c(CC(=O)O)sc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A20 compound treatment 0.331 0.0204 1.64 0.351 0.0321 2.91 3.2181 0.9632 1505283 Maybridge3_004244 CN(C)c1ccc(cc1)C2CC(=O)c3ccccc3N2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A21 compound treatment 0.304 -0.00662 -0.53 0.312 -0.00694 -0.63 -0.8225 -0.9966 2077439 Maybridge3_004245 CC(=O)n1nccc1c2sc3ccc(Cl)cc3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A22 compound treatment 0.313 0.00238 0.19 0.326 0.00706 0.64 0.5885 0.8797 2077440 Maybridge3_004246 COC(=O)/C(=C(\C#N)/c1ccc(Br)o1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A23 mock treatment 0.299 -0.0116 -0.94 0.31 -0.00894 -0.81 -1.2356 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 A24 positive control 0.083 -0.228 -18.33 0.09 -0.229 -20.78 -27.6555 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B01 compound treatment 0.324 0.0134 1.08 0.332 0.0131 1.19 1.6 0.9988 1206906 Maybridge3_004247 CC(C)NS(=O)(=O)c1ccccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B02 compound treatment 0.327 0.0164 1.32 0.334 0.0151 1.37 1.8992 0.9998 1026719 Maybridge3_004248 CCOC(=O)C1CCCNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B03 compound treatment 0.319 0.00838 0.67 0.325 0.00606 0.55 0.866 0.9949 2077441 Maybridge3_004249 CNC(=O)c1cccc2cccc(I)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B04 compound treatment 0.322 0.0114 0.92 0.328 0.00906 0.82 1.2294 0.9986 1136063 Maybridge3_004250 O=c1cc(oc2cc(OCC#N)ccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B05 compound treatment 0.326 0.0154 1.24 0.324 0.00506 0.46 1.2004 0.909 1534576 Maybridge3_004251 CCC(=O)N1CC(C)C(=O)N(C(=O)CC)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B06 compound treatment 0.317 0.00638 0.51 0.326 0.00706 0.64 0.8163 0.9939 1259836 Maybridge3_004252 Oc1c(c2ccccc2)c(=O)[nH]c3c(F)cccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B07 compound treatment 0.316 0.00538 0.43 0.327 0.00806 0.73 0.8235 0.9686 2077442 Maybridge3_004253 FC(F)(F)c1ccc2cccc(c2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B08 compound treatment 0.322 0.0114 0.92 0.327 0.00806 0.73 1.1652 0.9938 1228912 Maybridge3_004254 CC(=O)Nc1ccc(NC(=O)COc2ccc(C)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B09 compound treatment 0.319 0.00838 0.67 0.333 0.0141 1.28 1.3795 0.9555 1325300 Maybridge3_004255 CN(C)c1ccc(cc1)C(=O)N2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B10 compound treatment 0.317 0.00638 0.51 0.323 0.00406 0.37 0.6237 0.9868 1523654 Maybridge3_004256 CCOC(=O)c1cc(nc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B11 compound treatment 0.318 0.00738 0.59 0.331 0.0121 1.09 1.1942 0.9587 1069437 Maybridge3_004257 O=C1CSC(=S)N1Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B12 compound treatment 0.35 0.0394 3.17 0.353 0.0341 3.09 4.4283 0.9999 1041773 Maybridge3_004258 CC(O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B13 compound treatment 0.318 0.00738 0.59 0.324 0.00506 0.46 0.7449 0.992 2077443 Maybridge3_004259 CCOC(=O)c1c(OC)cccc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B14 compound treatment 0.323 0.0124 1.0 0.329 0.0101 0.91 1.3505 0.9991 2077444 Maybridge3_004260 CCOC(=O)c1cnc(S/C=C/C(=O)c2ccccc2)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B15 compound treatment 0.321 0.0104 0.84 0.334 0.0151 1.37 1.5575 0.9721 1520576 Maybridge3_004261 Cc1ccc2NC(=O)C(O)(C(=O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B16 compound treatment 0.309 -0.00162 -0.13 0.322 0.00306 0.28 0.104 0.3386 2077445 Maybridge3_004262 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(C)cc1)/Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B17 compound treatment 0.325 0.0144 1.16 0.328 0.00906 0.82 1.4002 0.986 2077446 Maybridge3_004263 OC1C2CC3CC(C2)C(C1C3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B18 compound treatment 0.324 0.0134 1.08 0.337 0.0181 1.64 1.9209 0.9792 2077447 Maybridge3_004264 CC1(C)SC(NC1C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B19 compound treatment 0.327 0.0164 1.32 0.332 0.0131 1.19 1.7708 0.9986 1291144 Maybridge3_004265 CCOC(=O)CC(C)Nc1cc(NC(=O)C)ccc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B20 compound treatment 0.32 0.00938 0.75 0.333 0.0141 1.28 1.4364 0.9686 2077448 Maybridge3_004266 COc1ccc(C)cc1NC(=O)CSc2nnc(n2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B21 compound treatment 0.322 0.0114 0.92 0.332 0.0131 1.19 1.4861 0.9919 2077449 Maybridge3_004267 C/C=C(/C(=O)O)\c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B22 compound treatment 0.319 0.00838 0.67 0.329 0.0101 0.91 1.1227 0.9889 1226092 Maybridge3_004268 Oc1c(Cc2ccccc2)c(=O)oc3c4ccccc4[nH]c(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B23 mock treatment 0.313 0.00238 0.19 0.32 0.00106 0.1 0.2034 0.9498 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 B24 positive control 0.082 -0.229 -18.41 0.085 -0.234 -21.23 -28.0334 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C01 compound treatment 0.315 0.00438 0.35 0.33 0.0111 1.0 0.9592 0.9013 2077450 Maybridge3_004269 CCOC(=O)c1ccc(s1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C02 compound treatment 0.324 0.0134 1.08 0.339 0.0201 1.82 2.0493 0.9686 2077451 Maybridge3_004270 Fc1ccc(NC(=O)CSc2nccc(n2)c3ccco3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C03 compound treatment 0.359 0.0484 3.9 0.358 0.0391 3.55 5.2617 0.9989 2077452 Maybridge3_004271 CS/C(=C/C(=O)c1cccs1)/Nc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C04 compound treatment 0.323 0.0124 1.0 0.321 0.00206 0.19 0.837 0.8255 2077453 Maybridge3_004272 Cc1c(/C=C(\C#N)/S(=O)(=O)C(C)(C)C)sc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C05 compound treatment 0.314 0.00338 0.27 0.328 0.00906 0.82 0.7739 0.8932 1371328 Maybridge3_004273 COc1ccc(Nc2nnns2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C06 compound treatment 0.321 0.0104 0.84 0.321 0.00206 0.19 0.7231 0.8446 1544653 Maybridge3_004274 Clc1ccc(s1)C(=O)CCNc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C07 compound treatment 0.313 0.00238 0.19 0.329 0.0101 0.91 0.7811 0.837 1586142 Maybridge3_004275 CCOC(=O)c1cnc(NCc2ccccc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C08 compound treatment 0.305 -0.00562 -0.45 0.32 0.00106 0.1 -0.2521 -0.5443 1689576 Maybridge3_004276 Clc1ccccc1c2snc(N3CCSCC3)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C09 compound treatment 0.317 0.00638 0.51 0.319 6.25E-5 0.01 0.367 0.7149 2077454 Maybridge3_004277 O=C(Cc1ccc2OCOc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C10 compound treatment 0.318 0.00738 0.59 0.33 0.0111 1.0 1.13 0.9686 2077455 Maybridge3_004278 c1sc(nc1c2nnc(o2)c3ccccc3)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C11 compound treatment 0.307 -0.00362 -0.29 0.321 0.00206 0.19 -0.074 -0.2135 2077456 Maybridge3_004279 CC(C)(C)C(=O)Nc1ncccc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C12 compound treatment 0.319 0.00838 0.67 0.332 0.0131 1.19 1.3153 0.9642 1170601 Maybridge3_004280 COC(=S)Nc1ccc(cc1)N2CC(C)OC(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C13 compound treatment 0.308 -0.00262 -0.21 0.326 0.00706 0.64 0.3038 0.4501 2077457 Maybridge3_004281 Cc1c(CO)cnn1c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C14 compound treatment 0.321 0.0104 0.84 0.332 0.0131 1.19 1.4292 0.9853 2077458 Maybridge3_004282 COC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C15 compound treatment 0.313 0.00238 0.19 0.323 0.00406 0.37 0.396 0.9533 1149660 Maybridge3_004283 Cc1nc2ccc(NC(=O)c3ccccc3C)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C16 compound treatment 0.332 0.0214 1.72 0.343 0.0241 2.18 2.7616 0.993 1285281 Maybridge3_004284 O=C(CSc1ccccn1)Nc2ccc(cc2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C17 compound treatment 0.32 0.00938 0.75 0.324 0.00506 0.46 0.8588 0.9717 2077459 Maybridge3_004285 Cc1ccc2scc(CC#N)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C18 compound treatment 0.315 0.00438 0.35 0.328 0.00906 0.82 0.8308 0.9284 2077460 Maybridge3_004286 Cc1ccc(F)cc1NC(=O)CSc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C19 compound treatment 0.323 0.0124 1.0 0.321 0.00206 0.19 0.837 0.8255 2077461 Maybridge3_004287 N/C(=N\O)/Cc1csc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C20 compound treatment 0.31 -6.25E-4 -0.05 0.33 0.0111 1.0 0.6745 0.6708 2077462 Maybridge3_004288 CSc1nn(c[n+]1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C21 compound treatment 0.321 0.0104 0.84 0.328 0.00906 0.82 1.1724 1.0 1432056 Maybridge3_004289 Fc1ccc(NC(=O)CSC2=NCCc3ccccc23)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C22 compound treatment 0.311 3.75E-4 0.03 0.331 0.0121 1.09 0.7956 0.7263 1559640 Maybridge3_004290 O=S(=O)(CC#N)c1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C23 mock treatment 0.312 0.00138 0.11 0.31 -0.00894 -0.81 -0.4954 -0.605 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 C24 positive control 0.084 -0.227 -18.25 0.087 -0.232 -21.05 -27.7911 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D01 compound treatment 0.328 0.0174 1.4 0.333 0.0141 1.28 1.8919 0.999 1458258 Maybridge3_004291 CCCNS(=O)(=O)c1ccc(Cl)cc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D02 compound treatment 0.321 0.0104 0.84 0.333 0.0141 1.28 1.4934 0.9789 1642194 Maybridge3_004292 Nc1cc(c2ccccc2)n3c4ccccc4nc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D03 compound treatment 0.086 -0.225 -18.09 0.097 -0.222 -20.15 -27.0354 -0.9986 2077463 Maybridge3_004293 COC(=O)c1cccc2cccc(I)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D04 compound treatment 0.33 0.0194 1.56 0.34 0.0211 1.91 2.4551 0.9949 1426948 Maybridge3_004294 CCOC(=O)c1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D05 compound treatment 0.323 0.0124 1.0 0.336 0.0171 1.55 1.7998 0.9773 1487593 Maybridge3_004295 CC(=O)N1CCC(=O)Nc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D06 compound treatment 0.319 0.00838 0.67 0.331 0.0121 1.09 1.2511 0.9729 2077464 Maybridge3_004296 Oc1c(/C=N/c2ccc(Cl)cc2)c(=O)oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D07 compound treatment 0.33 0.0194 1.56 0.33 0.0111 1.0 1.8133 0.9773 2077465 Maybridge3_004297 Cc1cc(O)c2ccc(cc2n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D08 compound treatment 0.323 0.0124 1.0 0.332 0.0131 1.19 1.5431 0.9963 2077466 Maybridge3_004298 COc1ccc(C/N=C(\C)/C2CCOC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D09 compound treatment 0.321 0.0104 0.84 0.332 0.0131 1.19 1.4292 0.9853 2077467 Maybridge3_004299 CC(=O)OC(OC(=O)C)c1ccc(cc1)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D10 compound treatment 0.332 0.0214 1.72 0.341 0.0221 2.0 2.6332 0.9972 1149480 Maybridge3_004300 CC(=O)OC12CCC(=O)C=C2CCC3C4CCC(=O)C4(C)CCC31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D11 compound treatment 0.322 0.0114 0.92 0.332 0.0131 1.19 1.4861 0.9919 2077468 Maybridge3_004301 COCc1snnc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D12 compound treatment 0.337 0.0264 2.12 0.345 0.0261 2.37 3.1746 0.9986 2077469 Maybridge3_004302 CCC1=C2CCC3C4CCC(C)(O)C4(C)CCC3C2(C)CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D13 compound treatment 0.322 0.0114 0.92 0.33 0.0111 1.0 1.3577 0.9989 1223799 Maybridge3_004303 CC(O)C(NC(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D14 compound treatment 0.316 0.00538 0.43 0.328 0.00906 0.82 0.8877 0.955 2077470 Maybridge3_004304 Cc1nc(S/C=C/C(=O)c2ccccc2)c(C#N)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D15 compound treatment 0.317 0.00638 0.51 0.334 0.0151 1.37 1.3298 0.9105 1502044 Maybridge3_004305 CCc1c(N)c2ccccc2[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D16 compound treatment 0.323 0.0124 1.0 0.331 0.0121 1.09 1.4789 0.9989 2077471 Maybridge3_004306 CSC(=CC(=O)c1cccc2ccccc12)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D17 compound treatment 0.327 0.0164 1.32 0.339 0.0201 1.82 2.2201 0.9874 1616062 Maybridge3_004307 CCOC(=O)C1(CC(=O)C2(CC1=O)C(=O)OCC)CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D18 compound treatment 0.325 0.0144 1.16 0.335 0.0161 1.46 1.8495 0.9935 1072154 Maybridge3_004308 CC1(C)SCNC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D19 compound treatment 0.328 0.0174 1.4 0.335 0.0161 1.46 2.0203 0.9998 1252396 Maybridge3_004309 CCN(CCN1C(=O)CCC1=O)c2cccc(NC(=O)C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D20 compound treatment 0.353 0.0424 3.41 0.355 0.0361 3.27 4.7275 0.9998 1627990 Maybridge3_004310 CCOc1ccc(cc1)C(=O)CC(SCc2ccc(Cl)cc2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D21 compound treatment 0.322 0.0114 0.92 0.335 0.0161 1.46 1.6787 0.9749 2077472 Maybridge3_004311 CN(C)c1ccc(cc1)C(=C(C)C)/C(=N/O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D22 compound treatment 0.369 0.0584 4.7 0.369 0.0501 4.54 6.5372 0.9999 2077473 Maybridge3_004312 Fc1ccc(cc1)C(=O)/C=C\Nc2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D23 mock treatment 0.306 -0.00462 -0.37 0.321 0.00206 0.19 -0.131 -0.3142 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 D24 positive control 0.086 -0.225 -18.09 0.088 -0.231 -20.96 -27.6131 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E01 compound treatment 0.326 0.0154 1.24 0.334 0.0151 1.37 1.8423 0.9988 2077474 Maybridge3_004313 Clc1ccc(cc1)c2cc(cs2)C(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E02 compound treatment 0.321 0.0104 0.84 0.337 0.0181 1.64 1.7501 0.9511 2077475 Maybridge3_004314 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3csc(Cc4ccsc4)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E03 compound treatment 0.357 0.0464 3.73 0.356 0.0371 3.36 5.0195 0.9986 2077476 Maybridge3_004315 CS/C(=C/C(=O)c1ccco1)/Nc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E04 compound treatment 0.319 0.00838 0.67 0.326 0.00706 0.64 0.9302 0.9997 1543021 Maybridge3_004316 Cc1ccsc1C2CC(=O)Nc3ccccc3S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E05 compound treatment 0.316 0.00538 0.43 0.335 0.0161 1.46 1.337 0.8791 2077477 Maybridge3_004317 Cc1ccc(c2csc(n2)c3cccnc3)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E06 compound treatment 0.323 0.0124 1.0 0.327 0.00806 0.73 1.2221 0.9885 1648360 Maybridge3_004318 CC(C)c1ccc(NCCC(=O)c2ccc(Cl)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E07 compound treatment 0.319 0.00838 0.67 0.333 0.0141 1.28 1.3795 0.9555 1592584 Maybridge3_004319 OC(=O)c1cnc(NCc2ccccc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E08 compound treatment 0.311 3.75E-4 0.03 0.328 0.00906 0.82 0.603 0.7326 2077478 Maybridge3_004320 Fc1cccc(Sc2ccc(Cl)cc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E09 compound treatment 0.32 0.00938 0.75 0.335 0.0161 1.46 1.5648 0.9531 2077479 Maybridge3_004321 NC(=O)c1cccc(CC(=O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E10 compound treatment 0.279 -0.0316 -2.55 0.3 -0.0189 -1.72 -3.0163 -0.9817 2077480 Maybridge3_004322 CN(C)CCC(=O)/C=C/c1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E11 compound treatment 0.324 0.0134 1.08 0.333 0.0141 1.28 1.6642 0.9964 2077481 Maybridge3_004323 Cc1c(cnn1c2ccccc2C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E12 compound treatment 0.317 0.00638 0.51 0.323 0.00406 0.37 0.6237 0.9868 2077482 Maybridge3_004324 COC(=S)Nc1c(Br)cc(C)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E13 compound treatment 0.319 0.00838 0.67 0.329 0.0101 0.91 1.1227 0.9889 2077483 Maybridge3_004325 CCOC(=O)c1cccc(O)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E14 compound treatment 0.167 -0.144 -11.57 0.195 -0.124 -11.25 -16.1331 -0.9999 2077484 Maybridge3_004326 Clc1ccc(cc1)C(=O)CCSc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E15 compound treatment 0.327 0.0164 1.32 0.331 0.0121 1.09 1.7066 0.9957 2077485 Maybridge3_004327 Cc1nc2ccc(NC(=O)c3ccccc3C(F)(F)F)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E16 compound treatment 0.321 0.0104 0.84 0.336 0.0171 1.55 1.6859 0.958 1287180 Maybridge3_004328 Cn1ccnc1SCC(=O)Nc2ccc(cc2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E17 compound treatment 0.322 0.0114 0.92 0.328 0.00906 0.82 1.2294 0.9986 2077486 Maybridge3_004329 COC(=O)Cc1csc2ccc(C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E18 compound treatment 0.315 0.00438 0.35 0.334 0.0151 1.37 1.2159 0.8612 2077487 Maybridge3_004330 COc1ccc(Br)cc1/C=C/C(=O)Nc2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E19 compound treatment 0.321 0.0104 0.84 0.334 0.0151 1.37 1.5575 0.9721 2077488 Maybridge3_004331 CNC(=O)Cc1sc2ccc(Cl)cc2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E20 compound treatment 0.323 0.0124 1.0 0.336 0.0171 1.55 1.7998 0.9773 2077489 Maybridge3_004332 CC/1=NOC(=O)\C1=C/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E21 compound treatment 0.323 0.0124 1.0 0.334 0.0151 1.37 1.6714 0.9879 2077490 Maybridge3_004333 O=C(Nc1csc(Cc2ccsc2)n1)Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E22 compound treatment 0.319 0.00838 0.67 0.324 0.00506 0.46 0.8018 0.9825 1347797 Maybridge3_004334 OC(=O)c1cccc(Sc2cccc(c2)C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E23 mock treatment 0.303 -0.00762 -0.61 0.314 -0.00494 -0.45 -0.7511 -0.988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 E24 positive control 0.088 -0.223 -17.93 0.09 -0.229 -20.78 -27.3708 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F01 compound treatment 0.326 0.0154 1.24 0.331 0.0121 1.09 1.6497 0.9981 1134456 Maybridge3_004335 Cc1cc(I)c(cc1C)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F02 compound treatment 0.337 0.0264 2.12 0.343 0.0241 2.18 3.0463 0.9999 2077491 Maybridge3_004336 O=c1[nH]c(SCc2ccccc2)nc(c1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F03 compound treatment 0.233 -0.0776 -6.25 0.273 -0.0459 -4.17 -7.3685 -0.9806 2077492 Maybridge3_004337 NC(=O)c1cccc2cccc(Br)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F04 compound treatment 0.345 0.0344 2.77 0.361 0.0421 3.82 4.6571 0.9875 1020609 Maybridge3_004338 S=c1cc(oc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F05 compound treatment 0.328 0.0174 1.4 0.335 0.0161 1.46 2.0203 0.9998 1182196 Maybridge3_004339 CN1C(=O)CC(Nc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F06 compound treatment 0.324 0.0134 1.08 0.33 0.0111 1.0 1.4716 0.9994 2077493 Maybridge3_004340 O=C1CCCC(=O)C1=CNc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F07 compound treatment 0.312 0.00138 0.11 0.334 0.0151 1.37 1.0451 0.7619 1628342 Maybridge3_004341 COc1ccc2C(=O)CC(Oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F08 compound treatment 0.328 0.0174 1.4 0.336 0.0171 1.55 2.0845 0.9987 2077494 Maybridge3_004342 C/C(=N\CCc1ccccc1)/C2CCOC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F09 compound treatment 0.322 0.0114 0.92 0.34 0.0211 1.91 1.9996 0.9432 2077495 Maybridge3_004343 CCC(=O)N1CCCc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F10 compound treatment 0.328 0.0174 1.4 0.335 0.0161 1.46 2.0203 0.9998 2077496 Maybridge3_004344 CC12CCC3C(CCC4=CC(=O)/C(=C(/O)\C(F)(F)F)/CC34C)C2CCC1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F11 compound treatment 0.285 -0.0256 -2.06 0.31 -0.00894 -0.81 -2.0328 -0.9168 2077497 Maybridge3_004345 COc1ccc(N/C=C\C(=S)c2ccc(OC)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F12 compound treatment 0.346 0.0354 2.85 0.358 0.0391 3.55 4.5215 0.9941 1037327 Maybridge3_004346 COc1ccc2C3CCC4(C)C(O)CCC4C3CCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F13 compound treatment 0.318 0.00738 0.59 0.328 0.00906 0.82 1.0016 0.9872 2077498 Maybridge3_004347 COc1ccc(cc1)C(=O)/C(=N\O)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F14 compound treatment 0.328 0.0174 1.4 0.347 0.0281 2.55 2.7905 0.9602 2077499 Maybridge3_004348 Fc1cc2[nH]c(S/C=C/C(=O)c3ccccc3)nc2cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F15 compound treatment 0.321 0.0104 0.84 0.34 0.0211 1.91 1.9427 0.9311 1354609 Maybridge3_004349 Oc1cc(=O)n(c2ccccc2)c3CCCCCc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F16 compound treatment 0.334 0.0234 1.88 0.348 0.0291 2.64 3.1964 0.9863 2077500 Maybridge3_004350 O=C(C(=C1SCCCS1)C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F17 compound treatment 0.326 0.0154 1.24 0.34 0.0211 1.91 2.2274 0.9779 1537567 Maybridge3_004351 CC(=O)OC1(CC2CC3C1)CC(C2)C3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F18 compound treatment 0.324 0.0134 1.08 0.345 0.0261 2.37 2.4344 0.9365 2077501 Maybridge3_004352 CC(=O)N1C(SC(C)(C)C1C(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F19 compound treatment 0.337 0.0264 2.12 0.337 0.0181 1.64 2.6612 0.9918 1687635 Maybridge3_004353 CCN1c2cc(NC(=O)C)ccc2C(C)CC1(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F20 compound treatment 0.318 0.00738 0.59 0.334 0.0151 1.37 1.3867 0.9303 2077502 Maybridge3_004354 Cc1ccc(NC(=O)CSc2ccc(cn2)C(F)(F)F)cc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F21 compound treatment 0.325 0.0144 1.16 0.338 0.0191 1.73 2.0421 0.9809 2077503 Maybridge3_004355 CC(C)(O)C1CCC(C)(C)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F22 compound treatment 0.318 0.00738 0.59 0.332 0.0131 1.19 1.2584 0.9489 2077504 Maybridge3_004356 Cc1c(cnn1c2ccccc2)c3nnnn3c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F23 mock treatment 0.31 -6.25E-4 -0.05 0.318 -9.37E-4 -0.09 -0.0958 -0.9686 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 F24 positive control 0.087 -0.224 -18.01 0.09 -0.229 -20.78 -27.4278 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G01 compound treatment 0.327 0.0164 1.32 0.326 0.00706 0.64 1.3857 0.9451 2077505 Maybridge3_004357 CC(C)(C)c1ccc(s1)C(=O)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G02 compound treatment 0.307 -0.00362 -0.29 0.32 0.00106 0.1 -0.1382 -0.4496 2077506 Maybridge3_004358 CSc1nnc(SCC(=O)c2sc3ccc(Cl)cc3c2C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G03 compound treatment 0.316 0.00538 0.43 0.329 0.0101 0.91 0.9519 0.9418 2077507 Maybridge3_004359 COc1ncnc2c3cccnc3sc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G04 compound treatment 0.32 0.00938 0.75 0.331 0.0121 1.09 1.3081 0.9835 1728465 Maybridge3_004360 O=C1CC(Sc2ccccc2N1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G05 compound treatment 0.436 0.125 10.1 0.44 0.121 10.99 14.9094 0.9991 2077508 Maybridge3_004361 Oc1c(Cl)cc(Cl)cc1/C=N/c2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G06 compound treatment 0.312 0.00138 0.11 0.329 0.0101 0.91 0.7242 0.7871 1731537 Maybridge3_004362 O=C(Nc1ccccc1)OC2CCCCc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G07 compound treatment 0.325 0.0144 1.16 0.333 0.0141 1.28 1.7211 0.9988 2077509 Maybridge3_004363 OC(=O)c1ccc(cc1)n2ccc(n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G08 compound treatment 0.28 -0.0306 -2.47 0.304 -0.0149 -1.36 -2.7026 -0.9603 1489588 Maybridge3_004364 Cc1ccc(Sc2cccc3nc(N)nc(N)c23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G09 compound treatment 0.321 0.0104 0.84 0.34 0.0211 1.91 1.9427 0.9311 2077510 Maybridge3_004365 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc3OCCc3c2)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G10 compound treatment 0.322 0.0114 0.92 0.336 0.0171 1.55 1.7429 0.9686 2077511 Maybridge3_004366 COc1ccc(cc1)c2nc(O)n(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G11 compound treatment 0.32 0.00938 0.75 0.329 0.0101 0.91 1.1797 0.9955 2077512 Maybridge3_004367 COc1ccc(cc1)c2ocnc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G12 compound treatment 0.311 3.75E-4 0.03 0.321 0.00206 0.19 0.1537 0.8107 2077513 Maybridge3_004368 CCCc1ccc(NC(=S)OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G13 compound treatment 0.326 0.0154 1.24 0.331 0.0121 1.09 1.6497 0.9981 2077514 Maybridge3_004369 NC(=O)c1cccc2OCCOc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G14 compound treatment 0.32 0.00938 0.75 0.343 0.0241 2.18 2.0783 0.8993 2077515 Maybridge3_004370 CSc1cccc(NC(=O)CSc2ccc(C)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G15 compound treatment 0.317 0.00638 0.51 0.331 0.0121 1.09 1.1372 0.9404 1671131 Maybridge3_004371 Cc1nc2ccc(NS(=O)(=O)c3ccc(F)c(Cl)c3)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G16 compound treatment 0.315 0.00438 0.35 0.318 -9.37E-4 -0.09 0.1889 0.5213 2077516 Maybridge3_004372 CSc1cccc(NC(=O)CSc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G17 compound treatment 0.326 0.0154 1.24 0.337 0.0181 1.64 2.0348 0.9904 2077517 Maybridge3_004373 CNC(=O)Cc1csc2ccc(C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G18 compound treatment 0.312 0.00138 0.11 0.329 0.0101 0.91 0.7242 0.7871 2077518 Maybridge3_004374 Fc1ccc(NC(=O)CSCc2ccc(Cl)c(Cl)c2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G19 compound treatment 0.329 0.0184 1.48 0.341 0.0221 2.0 2.4624 0.9889 1244286 Maybridge3_004375 Clc1ccc2scc(C(=O)Nc3ccccc3)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G20 compound treatment 0.329 0.0184 1.48 0.338 0.0191 1.73 2.2698 0.997 2077519 Maybridge3_004376 CC/1=NOC(=O)\C1=C/Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G21 compound treatment 0.326 0.0154 1.24 0.333 0.0141 1.28 1.7781 0.9999 1543906 Maybridge3_004377 Cc1ccc(NC(=O)c2csc(n2)c3cccnc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G22 compound treatment 0.321 0.0104 0.84 0.332 0.0131 1.19 1.4292 0.9853 1342753 Maybridge3_004378 COc1ccc(Sc2ccccc2C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G23 mock treatment 0.307 -0.00362 -0.29 0.318 -9.37E-4 -0.09 -0.2666 -0.8767 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 G24 positive control 0.088 -0.223 -17.93 0.092 -0.227 -20.6 -27.2425 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H01 compound treatment 0.329 0.0184 1.48 0.331 0.0121 1.09 1.8205 0.989 2077520 Maybridge3_004379 NS(=O)(=O)c1ccc(Br)cc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H02 compound treatment 0.319 0.00838 0.67 0.336 0.0171 1.55 1.572 0.9306 1449915 Maybridge3_004380 CSc1nnc2c3ccccc3c4ccccc4c2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H03 compound treatment 0.323 0.0124 1.0 0.33 0.0111 1.0 1.4147 1.0 1071869 Maybridge3_004381 CC(=O)Nc1ccccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H04 compound treatment 0.347 0.0364 2.93 0.354 0.0351 3.18 4.3217 0.9991 1708588 Maybridge3_004382 CC(C)Nc1c(oc2ccc(cc2c1=O)C(=O)O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H05 compound treatment 0.327 0.0164 1.32 0.337 0.0181 1.64 2.0917 0.9942 1416672 Maybridge3_004383 CC(C)CNS(=O)(=O)c1cccc2c(N)cccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H06 compound treatment 0.332 0.0214 1.72 0.346 0.0271 2.46 2.9541 0.9849 2077521 Maybridge3_004384 Fc1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H07 compound treatment 0.325 0.0144 1.16 0.337 0.0181 1.64 1.9779 0.9855 1027018 Maybridge3_004385 O=C(Cc1ccccc1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H08 compound treatment 0.323 0.0124 1.0 0.33 0.0111 1.0 1.4147 1.0 1074229 Maybridge3_004386 CCCC(=O)c1ccc(OC)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H09 compound treatment 0.326 0.0154 1.24 0.338 0.0191 1.73 2.099 0.9865 1060204 Maybridge3_004387 COC(=O)c1ccccc1c2ccccc2C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H10 compound treatment 0.335 0.0244 1.96 0.351 0.0321 2.91 3.4459 0.9816 2077522 Maybridge3_004388 CC(=O)OC1CCC2C3CCC4CC(=O)C(CC4(C)C3CCC12C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H11 compound treatment 0.308 -0.00262 -0.21 0.322 0.00306 0.28 0.0471 0.1349 2077523 Maybridge3_004389 c1nsc(c1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H12 compound treatment 0.338 0.0274 2.2 0.35 0.0311 2.82 3.5525 0.9926 2077524 Maybridge3_004390 CC(=O)OC1CCC2C3CC(O)C4(O)CC(CCC4(C)C3CCC12C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H13 compound treatment 0.32 0.00938 0.75 0.327 0.00806 0.73 1.0513 0.9999 1082564 Maybridge3_004391 N#CC(Sc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H14 compound treatment 0.327 0.0164 1.32 0.335 0.0161 1.46 1.9634 0.9987 2077525 Maybridge3_004392 CCSc1nc(C)c(C)c(=O)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H15 compound treatment 0.328 0.0174 1.4 0.341 0.0221 2.0 2.4054 0.9846 1695066 Maybridge3_004393 Oc1cc(=O)oc2cc(c3ccccc3)n(c4ccccc4)c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H16 compound treatment 0.39 0.0794 6.39 0.398 0.0791 7.18 9.5943 0.9983 1341797 Maybridge3_004394 Cc1ccc(cc1)C(=O)CSc2nc(N)c(s2)C(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H17 compound treatment 0.331 0.0204 1.64 0.34 0.0211 1.91 2.5121 0.9971 1141552 Maybridge3_004395 OC1CC2CC(C1C2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H18 compound treatment 0.321 0.0104 0.84 0.339 0.0201 1.82 1.8785 0.9376 2077526 Maybridge3_004396 CC1(C)SC(CNC(=O)Cc2ccccc2)NC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H19 compound treatment 0.327 0.0164 1.32 0.336 0.0171 1.55 2.0276 0.9968 1690515 Maybridge3_004397 COc1ccc2[nH]c(=O)c(c(O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H20 compound treatment 0.354 0.0434 3.49 0.357 0.0381 3.45 4.9129 1.0 2077527 Maybridge3_004398 OC(=O)C(CC(=O)c1ccc(Br)cc1)Sc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H21 compound treatment 0.321 0.0104 0.84 0.334 0.0151 1.37 1.5575 0.9721 1543044 Maybridge3_004399 Cc1ccc(cc1)S(=O)(=O)N2CC3CC2CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H22 compound treatment 0.327 0.0164 1.32 0.334 0.0151 1.37 1.8992 0.9998 1087333 Maybridge3_004400 OCC1OC(Oc2ccccc2)C(O)C(O)C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H23 mock treatment 0.308 -0.00262 -0.21 0.322 0.00306 0.28 0.0471 0.1349 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 H24 positive control 0.09 -0.221 -17.77 0.093 -0.226 -20.51 -27.0644 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I01 compound treatment 0.331 0.0204 1.64 0.332 0.0131 1.19 1.9986 0.9873 2077528 Maybridge3_004401 CC(C)(C)c1ccc(s1)C(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I02 compound treatment 0.338 0.0274 2.2 0.346 0.0271 2.46 3.2958 0.9985 2077529 Maybridge3_004402 Cc1c(sc2ccc(Cl)cc12)c3cc(N)n(C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I03 compound treatment 0.328 0.0174 1.4 0.34 0.0211 1.91 2.3412 0.9882 1126998 Maybridge3_004403 N(c1ccccc1)c2ncnc3c4cccnc4sc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I04 compound treatment 0.381 0.0704 5.67 0.389 0.0701 6.36 8.5042 0.9983 2077530 Maybridge3_004404 Cc1c(/C=C/C(=O)Nc2nccs2)sc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I05 compound treatment 0.324 0.0134 1.08 0.343 0.0241 2.18 2.306 0.9469 2077531 Maybridge3_004405 COc1cc(/C=N/c2nccs2)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I06 compound treatment 0.321 0.0104 0.84 0.342 0.0231 2.09 2.071 0.9188 1558276 Maybridge3_004406 Clc1ccc(cc1)C(=O)OC2CCCCc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I07 compound treatment 0.317 0.00638 0.51 0.337 0.0181 1.64 1.5223 0.8861 2077532 Maybridge3_004407 CC(C)(C)C(=O)Nc1ccncc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I08 compound treatment 0.327 0.0164 1.32 0.348 0.0291 2.64 2.7978 0.9486 2077533 Maybridge3_004408 FC(F)(F)c1ccc(SCCC(=O)c2ccco2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I09 compound treatment 0.335 0.0244 1.96 0.338 0.0191 1.73 2.6115 0.998 2077534 Maybridge3_004409 CNc1cccc(c1)c2ccc3nnc(C)n3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I10 compound treatment 0.339 0.0284 2.28 0.354 0.0351 3.18 3.8662 0.9868 2077535 Maybridge3_004410 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)c2ccccc2C(=O)NCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I11 compound treatment 0.327 0.0164 1.32 0.34 0.0211 1.91 2.2843 0.9836 2077536 Maybridge3_004411 OC(=O)c1cscc1S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I12 compound treatment 0.321 0.0104 0.84 0.332 0.0131 1.19 1.4292 0.9853 2077537 Maybridge3_004412 COC(=S)Nc1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I13 compound treatment 0.337 0.0264 2.12 0.34 0.0211 1.91 2.8537 0.9986 2077538 Maybridge3_004413 COC(=O)c1cc2cc(N)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I14 compound treatment 0.324 0.0134 1.08 0.335 0.0161 1.46 1.7926 0.9889 2077539 Maybridge3_004414 Cc1ccc(SCC(=O)Nc2ccc(F)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I15 compound treatment 0.303 -0.00762 -0.61 0.334 0.0151 1.37 0.5326 0.3554 1385906 Maybridge3_004415 Cc1nc2ccc(NS(=O)(=O)c3ccccc3Cl)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I16 compound treatment 0.315 0.00438 0.35 0.328 0.00906 0.82 0.8308 0.9284 2077540 Maybridge3_004416 CSc1cccc(NC(=O)CSc2ccc(cn2)C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I17 compound treatment 0.334 0.0234 1.88 0.343 0.0241 2.18 2.8754 0.9973 2077541 Maybridge3_004417 Cc1c(sc2ccccc12)C(=O)COC(=O)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I18 compound treatment 0.32 0.00938 0.75 0.337 0.0181 1.64 1.6932 0.938 1023352 Maybridge3_004418 CCN(CC)c1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I19 compound treatment 0.333 0.0224 1.8 0.344 0.0251 2.27 2.8827 0.9933 2077542 Maybridge3_004419 CCOC(=O)c1csc(n1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I20 compound treatment 0.33 0.0194 1.56 0.333 0.0141 1.28 2.0058 0.995 1145804 Maybridge3_004420 Cc1ccccc1NC2CC(C)(C)NC(C)(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I21 compound treatment 0.335 0.0244 1.96 0.34 0.0211 1.91 2.7398 0.9999 2077543 Maybridge3_004421 O=C(Oc1ccccc1)c2csc(n2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I22 compound treatment 0.324 0.0134 1.08 0.337 0.0181 1.64 1.9209 0.9792 1219458 Maybridge3_004422 Cc1ccccc1Sc2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I23 mock treatment 0.315 0.00438 0.35 0.322 0.00306 0.28 0.4457 0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 I24 positive control 0.09 -0.221 -17.77 0.093 -0.226 -20.51 -27.0644 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J01 compound treatment 0.33 0.0194 1.56 0.333 0.0141 1.28 2.0058 0.995 2077544 Maybridge3_004423 CNS(=O)(=O)c1cc(Br)ccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J02 compound treatment 0.326 0.0154 1.24 0.331 0.0121 1.09 1.6497 0.9981 1711579 Maybridge3_004424 CCOC(=O)CSc1nnc2c3ccccc3c4ccccc4c2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J03 compound treatment 0.319 0.00838 0.67 0.325 0.00606 0.55 0.866 0.9949 2077545 Maybridge3_004425 NC(=O)Cc1ccccc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J04 compound treatment 0.324 0.0134 1.08 0.335 0.0161 1.46 1.7926 0.9889 2077546 Maybridge3_004426 Oc1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J05 compound treatment 0.347 0.0364 2.93 0.344 0.0251 2.27 3.6799 0.9922 1235318 Maybridge3_004427 Nc1cccc2c(cccc12)S(=O)(=O)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J06 compound treatment 0.324 0.0134 1.08 0.34 0.0211 1.91 2.1135 0.9631 1729148 Maybridge3_004428 Oc1c(Cc2ccccc2)c(=O)[nH]c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J07 compound treatment 0.327 0.0164 1.32 0.335 0.0161 1.46 1.9634 0.9987 1571661 Maybridge3_004429 OC(=O)CSc1nc(c([nH]1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J08 compound treatment 0.402 0.0914 7.36 0.42 0.101 9.17 11.6897 0.994 2077547 Maybridge3_004430 O=c1[nH]c2ccccc2nc1c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J09 compound treatment 0.39 0.0794 6.39 0.404 0.0851 7.72 9.9794 0.9956 1517427 Maybridge3_004431 CCOC(=O)c1ccccc1C(=O)c2ccc(cc2)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J10 compound treatment 0.331 0.0204 1.64 0.351 0.0321 2.91 3.2181 0.9632 1311500 Maybridge3_004432 CC(=O)OC1CCC2C3CCC4CCC(=O)CC4(C)C3CCC12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J11 compound treatment 0.328 0.0174 1.4 0.335 0.0161 1.46 2.0203 0.9998 2077548 Maybridge3_004433 ClC1(Cl)CC1S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J12 compound treatment 0.311 3.75E-4 0.03 0.339 0.0201 1.82 1.3091 0.7187 2077549 Maybridge3_004434 CN(C)CC1CCC/C(=C\c2ccc(C)cc2)/C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J13 compound treatment 0.323 0.0124 1.0 0.334 0.0151 1.37 1.6714 0.9879 2077550 Maybridge3_004435 O[S+](CC#N)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J14 compound treatment 0.33 0.0194 1.56 0.34 0.0211 1.91 2.4551 0.9949 1433889 Maybridge3_004436 CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J15 compound treatment 0.32 0.00938 0.75 0.329 0.0101 0.91 1.1797 0.9955 2077551 Maybridge3_004437 Oc1c(/C=N/Cc2ccccc2)c(=O)[nH]c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J16 compound treatment 0.327 0.0164 1.32 0.338 0.0191 1.73 2.1559 0.991 2077552 Maybridge3_004438 CCOC(=O)/C(=C/1\NC(CO)C(O1)c2ccccc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J17 compound treatment 0.324 0.0134 1.08 0.328 0.00906 0.82 1.3433 0.9911 2077553 Maybridge3_004439 CN(C)C(=O)/C=C/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J18 compound treatment 0.323 0.0124 1.0 0.33 0.0111 1.0 1.4147 1.0 1065717 Maybridge3_004440 COc1ccc(CO)cc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J19 compound treatment 0.323 0.0124 1.0 0.341 0.0221 2.0 2.1207 0.9481 2077554 Maybridge3_004441 CC1C(C)C2(CO)CCC1CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J20 compound treatment 0.333 0.0224 1.8 0.338 0.0191 1.73 2.4976 0.9998 2077555 Maybridge3_004442 Cc1oc(cc(=O)c1C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J21 compound treatment 0.326 0.0154 1.24 0.339 0.0201 1.82 2.1632 0.9823 1037592 Maybridge3_004443 Cc1ccc(cc1)S(=O)(=O)NC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J22 compound treatment 0.36 0.0494 3.98 0.371 0.0521 4.73 6.1531 0.9963 2077556 Maybridge3_004444 CCOc1ccc(cc1)C2NC(CS2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J23 mock treatment 0.311 3.75E-4 0.03 0.32 0.00106 0.1 0.0895 0.8861 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 J24 positive control 0.09 -0.221 -17.77 0.093 -0.226 -20.51 -27.0644 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K01 compound treatment 0.327 0.0164 1.32 0.329 0.0101 0.91 1.5783 0.9839 2077557 Maybridge3_004445 N/C(=N\O)/C1CSc2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K02 compound treatment 0.332 0.0214 1.72 0.339 0.0201 1.82 2.5048 0.9996 2077558 Maybridge3_004446 C(Sc1nccc(n1)c2cccnc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K03 compound treatment 0.32 0.00938 0.75 0.33 0.0111 1.0 1.2439 0.9901 2077559 Maybridge3_004447 S(c1ccccc1)c2ncnc3c4cccnc4sc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K04 compound treatment 0.347 0.0364 2.93 0.373 0.0541 4.91 5.5412 0.9696 2077560 Maybridge3_004448 Cc1c(/C=C/C(=O)Nc2ccc(F)cc2)sc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K05 compound treatment 0.325 0.0144 1.16 0.337 0.0181 1.64 1.9779 0.9855 2077561 Maybridge3_004449 Cc1cccc(c1)C(=O)Nc2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K06 compound treatment 0.346 0.0354 2.85 0.353 0.0341 3.09 4.2006 0.9992 1336000 Maybridge3_004450 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc3ccc(cc3)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K07 compound treatment 0.322 0.0114 0.92 0.336 0.0171 1.55 1.7429 0.9686 2077562 Maybridge3_004451 CCOC(=O)c1ccc2n(C)nnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K08 compound treatment 0.318 0.00738 0.59 0.337 0.0181 1.64 1.5793 0.9057 1318124 Maybridge3_004452 Clc1cccc(Cl)c1SCCC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K09 compound treatment 0.322 0.0114 0.92 0.335 0.0161 1.46 1.6787 0.9749 2077563 Maybridge3_004453 CC(C)(C)C(=O)Nc1ccncc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K10 compound treatment 0.312 0.00138 0.11 0.336 0.0171 1.55 1.1735 0.7557 1429989 Maybridge3_004454 C1CN=C(O1)c2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K11 compound treatment 0.324 0.0134 1.08 0.336 0.0171 1.55 1.8567 0.9842 2077564 Maybridge3_004455 Cn1nc(cc1C(F)(F)F)c2ccc(CO)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K12 compound treatment 0.325 0.0144 1.16 0.335 0.0161 1.46 1.8495 0.9935 2077565 Maybridge3_004456 CSc1ccccc1C(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K13 compound treatment 0.314 0.00338 0.27 0.329 0.0101 0.91 0.838 0.8794 2077566 Maybridge3_004457 CC(C)(C)OC(=O)NCC1CCN(Cc2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K14 compound treatment 0.324 0.0134 1.08 0.332 0.0131 1.19 1.6 0.9988 2077567 Maybridge3_004458 FC(F)(F)c1cc(NC(=O)CSc2ccccn2)cc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K15 compound treatment 0.324 0.0134 1.08 0.338 0.0191 1.73 1.9851 0.974 2077568 Maybridge3_004459 CNC(=O)Cc1csc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K16 compound treatment 0.323 0.0124 1.0 0.336 0.0171 1.55 1.7998 0.9773 1604291 Maybridge3_004460 Fc1ccc(NC(=O)CCC(=O)N2CCCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K17 compound treatment 0.314 0.00338 0.27 0.329 0.0101 0.91 0.838 0.8794 2077569 Maybridge3_004461 Cc1c(sc2ccccc12)C(=O)COC(=O)c3ccccc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K18 compound treatment 0.331 0.0204 1.64 0.34 0.0211 1.91 2.5121 0.9971 2077570 Maybridge3_004462 Cn1c(SCC(=O)Nc2ccccc2C#N)nnc1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K19 compound treatment 0.321 0.0104 0.84 0.329 0.0101 0.91 1.2366 0.999 2077571 Maybridge3_004463 C/C(=N\O)/c1sc2ccccc2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K20 compound treatment 0.319 0.00838 0.67 0.338 0.0191 1.73 1.7004 0.9156 2077572 Maybridge3_004464 Clc1ccc(NC2=CC(CC2=O)N3CCN(CC3)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K21 compound treatment 0.331 0.0204 1.64 0.345 0.0261 2.37 2.833 0.984 2077573 Maybridge3_004465 O=C(Sc1ccccc1)c2csc(n2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K22 compound treatment 0.322 0.0114 0.92 0.334 0.0151 1.37 1.6145 0.981 1696488 Maybridge3_004466 OC(=O)CCSc1cccc2cccc(C(=O)O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K23 mock treatment 0.309 -0.00162 -0.13 0.319 6.25E-5 0.01 -0.0885 -0.6758 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 K24 positive control 0.092 -0.219 -17.61 0.094 -0.225 -20.42 -26.8863 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L01 compound treatment 0.332 0.0214 1.72 0.333 0.0141 1.28 2.1197 0.9892 1100609 Maybridge3_004467 OC(=O)c1cccc(C(=O)O)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L02 compound treatment 0.319 0.00838 0.67 0.328 0.00906 0.82 1.0586 0.9951 1604828 Maybridge3_004468 C1C(Oc2ccccc2-c3nnnn13)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L03 compound treatment 0.323 0.0124 1.0 0.337 0.0181 1.64 1.864 0.9715 1335712 Maybridge3_004469 COc1ccc(Sc2ccccc2C(=O)O)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L04 compound treatment 0.324 0.0134 1.08 0.336 0.0171 1.55 1.8567 0.9842 1513117 Maybridge3_004470 Clc1ccc(Sc2cc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L05 compound treatment 0.331 0.0204 1.64 0.337 0.0181 1.64 2.3195 1.0 1705456 Maybridge3_004471 CCCN(C)S(=O)(=O)c1cccc2c(N)cccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L06 compound treatment 0.348 0.0374 3.01 0.345 0.0261 2.37 3.801 0.9929 1414774 Maybridge3_004472 CCc1c(NCc2ccccc2)c3cccc4CCCn(c1=O)c43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L07 compound treatment 0.329 0.0184 1.48 0.342 0.0231 2.09 2.5266 0.9856 1717442 Maybridge3_004473 O=C1CSc2nc(c(c3ccccc3)n12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L08 compound treatment 0.315 0.00438 0.35 0.333 0.0141 1.28 1.1517 0.8697 1599003 Maybridge3_004474 COc1cc(Br)c(CNc2ccccc2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L09 compound treatment 0.329 0.0184 1.48 0.337 0.0181 1.64 2.2056 0.9987 2077574 Maybridge3_004475 Cc1cc(C)cc(c1)N2Cc3ccccc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L10 compound treatment 0.345 0.0344 2.77 0.345 0.0261 2.37 3.6302 0.9969 1181196 Maybridge3_004476 CC(=O)OC1CCC2C3CCC4CCCC(=O)C4(C)C3CCC12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L11 compound treatment 0.32 0.00938 0.75 0.337 0.0181 1.64 1.6932 0.938 1052259 Maybridge3_004477 ON(Cc1ccccc1)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L12 compound treatment 0.324 0.0134 1.08 0.337 0.0181 1.64 1.9209 0.9792 2077575 Maybridge3_004478 C/C(=N\O)/c1cc2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L13 compound treatment 0.345 0.0344 2.77 0.361 0.0421 3.82 4.6571 0.9875 1433629 Maybridge3_004479 COc1cc2ccccc2c(=O)c3ccsc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L14 compound treatment 0.323 0.0124 1.0 0.336 0.0171 1.55 1.7998 0.9773 2077576 Maybridge3_004480 C/C(=C(/C#N)\C(=O)N)/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L15 compound treatment 0.353 0.0424 3.41 0.356 0.0371 3.36 4.7917 1.0 1501326 Maybridge3_004481 CCN(CC)C(=O)Oc1cc(=O)n2CCCc3cccc1c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L16 compound treatment 0.325 0.0144 1.16 0.34 0.0211 1.91 2.1704 0.9711 2077577 Maybridge3_004482 OC(=O)C1CSC(N1)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L17 compound treatment 0.326 0.0154 1.24 0.341 0.0221 2.0 2.2915 0.9733 1088489 Maybridge3_004483 OC(=O)C1C(C2CCC1C=C2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L18 compound treatment 0.328 0.0174 1.4 0.332 0.0131 1.19 1.8278 0.9966 1012553 Maybridge3_004484 CSC(=N)Nc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L19 compound treatment 0.331 0.0204 1.64 0.339 0.0201 1.82 2.4479 0.9986 1207943 Maybridge3_004485 CC(C)(O)CC1(CO)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L20 compound treatment 0.336 0.0254 2.04 0.337 0.0181 1.64 2.6042 0.994 1262710 Maybridge3_004486 CN(C)C(=O)Oc1cc(=O)n(C)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L21 compound treatment 0.322 0.0114 0.92 0.336 0.0171 1.55 1.7429 0.9686 2077578 Maybridge3_004487 CC(C)N(CCC=C)S(=O)(=O)c1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L22 compound treatment 0.326 0.0154 1.24 0.328 0.00906 0.82 1.4571 0.9803 2077579 Maybridge3_004488 Cc1c(CC#N)ccc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L23 mock treatment 0.315 0.00438 0.35 0.32 0.00106 0.1 0.3173 0.8687 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 L24 positive control 0.092 -0.219 -17.61 0.093 -0.226 -20.51 -26.9505 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M01 compound treatment 0.325 0.0144 1.16 0.324 0.00506 0.46 1.1435 0.9181 1347415 Maybridge3_004489 CCOC(=O)C(C)c1nc2ccccc2[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M02 compound treatment 0.316 0.00538 0.43 0.325 0.00606 0.55 0.6952 0.9929 1473321 Maybridge3_004490 Cc1c(sc2ccc(Cl)cc12)c3cc4[nH]c(C)cc(=O)n4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M03 compound treatment 0.313 0.00238 0.19 0.329 0.0101 0.91 0.7811 0.837 2077580 Maybridge3_004491 CS/C(=C\C(=O)c1cccs1)/NCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M04 compound treatment 0.32 0.00938 0.75 0.331 0.0121 1.09 1.3081 0.9835 2077581 Maybridge3_004492 Cc1ccc(SCCC(=O)c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M05 compound treatment 0.356 0.0454 3.65 0.376 0.0571 5.18 6.2463 0.9854 2077582 Maybridge3_004493 O=C(CSC1=NCCCCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M06 compound treatment 0.338 0.0274 2.2 0.342 0.0231 2.09 3.039 0.9997 2077583 Maybridge3_004494 Cc1nn(C)c(C)c1Sc2nccc(n2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M07 compound treatment 0.315 0.00438 0.35 0.326 0.00706 0.64 0.7024 0.9603 2077584 Maybridge3_004495 OC(=O)C1CN(CCc2ccc(Cl)cc2)C(=O)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M08 compound treatment 0.323 0.0124 1.0 0.331 0.0121 1.09 1.4789 0.9989 1657437 Maybridge3_004496 NC(=O)c1csc(n1)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M09 compound treatment 0.321 0.0104 0.84 0.328 0.00906 0.82 1.1724 1.0 2077585 Maybridge3_004497 Nc1snnc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M10 compound treatment 0.316 0.00538 0.43 0.326 0.00706 0.64 0.7594 0.9817 1499323 Maybridge3_004498 COc1ccc(OC)c(c1)S(=O)(=O)NC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M11 compound treatment 0.313 0.00238 0.19 0.33 0.0111 1.0 0.8453 0.8269 2077586 Maybridge3_004499 Nc1snnc1c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M12 compound treatment 0.334 0.0234 1.88 0.342 0.0231 2.09 2.8113 0.9986 1536987 Maybridge3_004500 COc1ccc(OC)c(c1)C(=O)Nc2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M13 compound treatment 0.319 0.00838 0.67 0.327 0.00806 0.73 0.9944 0.9992 2077587 Maybridge3_004501 OC(=O)c1cccc(c1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M14 compound treatment 0.318 0.00738 0.59 0.33 0.0111 1.0 1.13 0.9686 2077588 Maybridge3_004502 O=C(CSc1ccccn1)Nc2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M15 compound treatment 0.322 0.0114 0.92 0.324 0.00506 0.46 0.9726 0.9491 2077589 Maybridge3_004503 CNC(=O)Cc1c(Cl)sc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M16 compound treatment 0.313 0.00238 0.19 0.318 -9.37E-4 -0.09 0.0751 0.3586 2077590 Maybridge3_004504 COc1ccc(Cl)cc1NC(=O)CSCc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M17 compound treatment 0.319 0.00838 0.67 0.334 0.0151 1.37 1.4437 0.947 1611295 Maybridge3_004505 Cc1c(sc2ccc(Cl)cc12)C(=O)Cn3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M18 compound treatment 0.318 0.00738 0.59 0.336 0.0171 1.55 1.5151 0.9134 2077591 Maybridge3_004506 Cc1cc(C)nc(SCC(=O)Nc2ccc(F)c(Cl)c2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M19 compound treatment 0.337 0.0264 2.12 0.344 0.0251 2.27 3.1105 0.9994 2077592 Maybridge3_004507 CNC(=O)n1nccc1c2sc3ccccc3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M20 compound treatment 0.321 0.0104 0.84 0.325 0.00606 0.55 0.9799 0.9795 1674705 Maybridge3_004508 CCc1cccc(C)c1NC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M21 compound treatment 0.306 -0.00462 -0.37 0.318 -9.37E-4 -0.09 -0.3235 -0.8468 2077593 Maybridge3_004509 Clc1ccccc1CSc2nccc(n2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M22 compound treatment 0.325 0.0144 1.16 0.328 0.00906 0.82 1.4002 0.986 1061817 Maybridge3_004510 CC(=O)Oc1ccc(OC(=O)C)c2C3CCC(C=C3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M23 mock treatment 0.308 -0.00262 -0.21 0.316 -0.00294 -0.27 -0.338 -0.9934 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 M24 positive control 0.093 -0.218 -17.52 0.095 -0.224 -20.33 -26.7652 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N01 compound treatment 0.328 0.0174 1.4 0.336 0.0171 1.55 2.0845 0.9987 2077594 Maybridge3_004511 CCc1cccc(CC)c1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N02 compound treatment 0.326 0.0154 1.24 0.328 0.00906 0.82 1.4571 0.9803 1147563 Maybridge3_004512 O=C1NCC(Oc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N03 compound treatment 0.322 0.0114 0.92 0.323 0.00406 0.37 0.9085 0.92 1693239 Maybridge3_004513 CC(=O)Nc1ccc(Sc2ccccc2C(=O)O)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N04 compound treatment 0.389 0.0784 6.31 0.408 0.0891 8.08 10.1792 0.9925 2077595 Maybridge3_004514 Oc1c(/C=N/c2ccccc2)c(=O)n3CCCc4cccc1c43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N05 compound treatment 0.32 0.00938 0.75 0.327 0.00806 0.73 1.0513 0.9999 2077596 Maybridge3_004515 CC(=O)Oc1cccc2OCCOc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N06 compound treatment 0.193 -0.118 -9.47 0.2 -0.119 -10.8 -14.3317 -0.9979 2077597 Maybridge3_004516 COc1cc(Cl)ccc1N=NN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N07 compound treatment 0.322 0.0114 0.92 0.336 0.0171 1.55 1.7429 0.9686 1623379 Maybridge3_004517 CC(Sc1nc(c([nH]1)c2ccccc2)c3ccccc3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N08 compound treatment 0.311 3.75E-4 0.03 0.326 0.00706 0.64 0.4747 0.7396 1180481 Maybridge3_004518 CC(C)N1C(=O)c2ccccc2N(Cc3ccccc3)S1(=O)=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N09 compound treatment 0.32 0.00938 0.75 0.336 0.0171 1.55 1.629 0.9454 2077598 Maybridge3_004519 N#Cc1ccc(cc1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N10 compound treatment 0.354 0.0434 3.49 0.355 0.0361 3.27 4.7845 0.9995 2077599 Maybridge3_004520 CC(=O)OC1CCC2(C)C3C(CCC2(C)C1)C4CCC(=O)C4(C)CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N11 compound treatment 0.319 0.00838 0.67 0.333 0.0141 1.28 1.3795 0.9555 2077600 Maybridge3_004521 N#CC(N1CCSCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N12 compound treatment 0.334 0.0234 1.88 0.339 0.0201 1.82 2.6187 0.9999 2077601 Maybridge3_004522 Clc1ccc(cc1)C(=O)c2[n+](NC#N)ccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N13 compound treatment 0.33 0.0194 1.56 0.334 0.0151 1.37 2.07 0.9978 1710377 Maybridge3_004523 OC(=O)CCC1(CCC(=O)O)C(=O)c2cccc3cccc1c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N14 compound treatment 0.331 0.0204 1.64 0.338 0.0191 1.73 2.3837 0.9996 1484203 Maybridge3_004524 OC(=O)CCc1nc2ccccc2n1CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N15 compound treatment 0.326 0.0154 1.24 0.332 0.0131 1.19 1.7139 0.9998 1494942 Maybridge3_004525 Oc1cc(=O)oc2c3ccccc3n(Cc4ccccc4)c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N16 compound treatment 0.33 0.0194 1.56 0.332 0.0131 1.19 1.9416 0.9908 2077602 Maybridge3_004526 OC(=O)C1CSC(N1)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N17 compound treatment 0.327 0.0164 1.32 0.326 0.00706 0.64 1.3857 0.9451 2077603 Maybridge3_004527 CSC(C)/C(=N/O)/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N18 compound treatment 0.33 0.0194 1.56 0.336 0.0171 1.55 2.1984 1.0 2077604 Maybridge3_004528 COc1ccccc1c2nnc(SCC(=O)O)n2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N19 compound treatment 0.328 0.0174 1.4 0.334 0.0151 1.37 1.9561 0.9999 1032049 Maybridge3_004529 C1OC(OCC12COC(OC2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N20 compound treatment 0.326 0.0154 1.24 0.336 0.0171 1.55 1.9706 0.9938 2077605 Maybridge3_004530 CN1C(=O)OC(C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N21 compound treatment 0.328 0.0174 1.4 0.332 0.0131 1.19 1.8278 0.9966 2077606 Maybridge3_004531 CCCCN(C(C)(C)C)S(=O)(=O)c1ccc(C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N22 compound treatment 0.333 0.0224 1.8 0.348 0.0291 2.64 3.1394 0.9827 2077607 Maybridge3_004532 N#CCc1ccc2cc(CC#N)ccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N23 mock treatment 0.316 0.00538 0.43 0.321 0.00206 0.19 0.4384 0.9297 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 N24 positive control 0.092 -0.219 -17.61 0.095 -0.224 -20.33 -26.8221 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O01 compound treatment 0.36 0.0494 3.98 0.36 0.0411 3.73 5.4471 0.9995 2077608 Maybridge3_004533 CS/C(=C\C(=O)c1ccccc1)/Nc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O02 compound treatment 0.352 0.0414 3.33 0.36 0.0411 3.73 4.9915 0.9984 1675487 Maybridge3_004534 CC(=O)Nc1cc(n[nH]1)c2sc3ccc(Cl)cc3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O03 compound treatment 0.337 0.0264 2.12 0.338 0.0191 1.73 2.7253 0.9948 2077609 Maybridge3_004535 CS/C(=C\C(=O)c1cccs1)/NCc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O04 compound treatment 0.361 0.0504 4.06 0.374 0.0551 5.0 6.4026 0.9946 2077610 Maybridge3_004536 CNC(=O)n1nc(C)c(Cc2csc3ccc(Cl)cc23)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O05 compound treatment 0.326 0.0154 1.24 0.326 0.00706 0.64 1.3288 0.9531 1561799 Maybridge3_004537 OC(=O)c1ccc2NCCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O06 compound treatment 0.327 0.0164 1.32 0.329 0.0101 0.91 1.5783 0.9839 1210511 Maybridge3_004538 Cn1cnc(n1)c2ccccc2NS(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O07 compound treatment 0.316 0.00538 0.43 0.329 0.0101 0.91 0.9519 0.9418 2077611 Maybridge3_004539 CN(C)c1ccc(cc1)C(=O)Cc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O08 compound treatment 0.329 0.0184 1.48 0.331 0.0121 1.09 1.8205 0.989 2077612 Maybridge3_004540 NC(=O)c1ccc(OCC(F)(F)F)c(C#N)c1OCC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O09 compound treatment 0.329 0.0184 1.48 0.338 0.0191 1.73 2.2698 0.997 2077613 Maybridge3_004541 COc1ccc(cc1)c2nnsc2N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O10 compound treatment 0.322 0.0114 0.92 0.33 0.0111 1.0 1.3577 0.9989 2077614 Maybridge3_004542 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O11 compound treatment 0.326 0.0154 1.24 0.334 0.0151 1.37 1.8423 0.9988 2077615 Maybridge3_004543 CCOC(=O)c1sc(Br)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O12 compound treatment 0.331 0.0204 1.64 0.341 0.0221 2.0 2.5763 0.9951 1278326 Maybridge3_004544 CSc1ccccc1C(=O)c2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O13 compound treatment 0.319 0.00838 0.67 0.332 0.0131 1.19 1.3153 0.9642 2077616 Maybridge3_004545 OC(=O)c1ccc(cc1)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O14 compound treatment 0.32 0.00938 0.75 0.333 0.0141 1.28 1.4364 0.9686 2077617 Maybridge3_004546 Fc1ccc(NC(=O)CSc2cccc(c2)C(F)(F)F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O15 compound treatment 0.332 0.0214 1.72 0.334 0.0151 1.37 2.1839 0.9935 2077618 Maybridge3_004547 CN(C)C(=O)Cc1c(Cl)sc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O16 compound treatment 0.328 0.0174 1.4 0.337 0.0181 1.64 2.1487 0.9969 1345518 Maybridge3_004548 Cn1ccnc1SCC(=O)Nc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O17 compound treatment 0.353 0.0424 3.41 0.375 0.0561 5.09 6.0112 0.9811 1365819 Maybridge3_004549 Cc1c(CC(=O)Nc2ccccc2)sc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O18 compound treatment 0.324 0.0134 1.08 0.33 0.0111 1.0 1.4716 0.9994 2077619 Maybridge3_004550 Cc1ccc(NC(=N)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O19 compound treatment 0.319 0.00838 0.67 0.33 0.0111 1.0 1.1869 0.9812 2077620 Maybridge3_004551 Cc1c(sc2ccccc12)c3ccnn3S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O20 compound treatment 0.561 0.25 20.16 0.564 0.245 22.24 29.9859 0.9988 2077621 Maybridge3_004552 N#CC(=C(C#N)c1ccco1)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O21 compound treatment 0.321 0.0104 0.84 0.327 0.00806 0.73 1.1083 0.9978 1467984 Maybridge3_004553 C(Sc1nccc(n1)c2ccco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O22 compound treatment 0.332 0.0214 1.72 0.339 0.0201 1.82 2.5048 0.9996 2077622 Maybridge3_004554 CS(=O)c1nc2ccccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O23 mock treatment 0.321 0.0104 0.84 0.326 0.00706 0.64 1.0441 0.9914 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 O24 positive control 0.093 -0.218 -17.52 0.097 -0.222 -20.15 -26.6368 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P01 compound treatment 0.328 0.0174 1.4 0.335 0.0161 1.46 2.0203 0.9998 2077623 Maybridge3_004555 CNC(=O)c1ccccc1[S+]2N(C)C(=O)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P02 compound treatment 0.327 0.0164 1.32 0.335 0.0161 1.46 1.9634 0.9987 2077624 Maybridge3_004556 Clc1ccc(cc1)c2cc(=O)c3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P03 compound treatment 0.324 0.0134 1.08 0.339 0.0201 1.82 2.0493 0.9686 1278035 Maybridge3_004557 CNC(=O)c1ccccc1Sc2ccccc2COC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P04 compound treatment 0.322 0.0114 0.92 0.332 0.0131 1.19 1.4861 0.9919 1002966 Maybridge3_004558 CCOC(=O)C(C(=O)Cc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P05 compound treatment 0.306 -0.00462 -0.37 0.308 -0.0109 -0.99 -0.9654 -0.9104 1647466 Maybridge3_004559 CN(C)CCC(=O)c1ccc2OCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P06 compound treatment 0.327 0.0164 1.32 0.327 0.00806 0.73 1.4499 0.9614 1240907 Maybridge3_004560 O=C(OC(CN1CCCCC1)CN2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P07 compound treatment 0.319 0.00838 0.67 0.333 0.0141 1.28 1.3795 0.9555 2077625 Maybridge3_004561 C/C(=N\O)/c1ccc2CCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P08 compound treatment 0.327 0.0164 1.32 0.335 0.0161 1.46 1.9634 0.9987 1350987 Maybridge3_004562 COCCC(=O)NC1(CC2CC3CC(C2)C1)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P09 compound treatment 0.328 0.0174 1.4 0.334 0.0151 1.37 1.9561 0.9999 1280828 Maybridge3_004563 CC(=O)N1CCN(CC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P10 compound treatment 0.353 0.0424 3.41 0.35 0.0311 2.82 4.4066 0.9955 2077626 Maybridge3_004564 CC(=O)OC1CCC2C3CCc4cc(OC(=O)C)ccc4C3C(C)(O)CC12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P11 compound treatment 0.305 -0.00562 -0.45 0.314 -0.00494 -0.45 -0.6372 -1.0 2077627 Maybridge3_004565 CCC1(C(=Nc2ccccc21)N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P12 compound treatment 0.319 0.00838 0.67 0.324 0.00506 0.46 0.8018 0.9825 2077628 Maybridge3_004566 FC(F)(F)c1cccc(c1)C(=O)c2ccc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P13 compound treatment 0.331 0.0204 1.64 0.345 0.0261 2.37 2.833 0.984 2077629 Maybridge3_004567 CCCCc1c(O)c2ccccc2n(CCCC)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P14 compound treatment 0.371 0.0604 4.86 0.37 0.0511 4.64 6.7153 0.9997 2077630 Maybridge3_004568 COc1ccc(cc1)C(=O)/C=C/Nc2ccc(Cl)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P15 compound treatment 0.324 0.0134 1.08 0.335 0.0161 1.46 1.7926 0.9889 1070215 Maybridge3_004569 CC1CCC(CC1)NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P16 compound treatment 0.329 0.0184 1.48 0.333 0.0141 1.28 1.9489 0.9973 2077631 Maybridge3_004570 CC1(C)SC(NC1C(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P17 compound treatment 0.327 0.0164 1.32 0.333 0.0141 1.28 1.835 0.9999 2077632 Maybridge3_004571 CC(=C(NC(=O)C)c1ccccc1)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P18 compound treatment 0.312 0.00138 0.11 0.328 0.00906 0.82 0.66 0.7951 2077633 Maybridge3_004572 Cc1ccnc(S/C=C/C(=O)c2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P19 compound treatment 0.324 0.0134 1.08 0.333 0.0141 1.28 1.6642 0.9964 1411270 Maybridge3_004573 OC(=O)C1(CCC2(CC1=O)C(=O)O)CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P20 compound treatment 0.325 0.0144 1.16 0.333 0.0141 1.28 1.7211 0.9988 1202234 Maybridge3_004574 CCCCc1c(O)c2ccc(C)cc2n(CC)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P21 compound treatment 0.329 0.0184 1.48 0.338 0.0191 1.73 2.2698 0.997 2077634 Maybridge3_004575 O/N=C(/CN1CCOCC1)\c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P22 compound treatment 0.262 -0.0486 -3.92 0.257 -0.0619 -5.62 -6.7442 -0.9844 2077635 Maybridge3_004576 COc1ccc2cccc3C(=O)C=Cc1c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P23 mock treatment 0.317 0.00638 0.51 0.326 0.00706 0.64 0.8163 0.9939 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1443 P24 positive control 0.094 -0.217 -17.44 0.099 -0.22 -19.96 -26.4515 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A01 compound treatment 0.307 0.00112 0.09 0.309 0.00681 0.62 0.5013 0.8021 1671681 Maybridge3_004577 Cc1cccc(Nc2ncncc2C#N)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A02 compound treatment 0.305 -8.75E-4 -0.07 0.309 0.00681 0.62 0.3874 0.6225 1656966 Maybridge3_004578 COc1ccc(cc1)C2C(C(=O)O)c3ccccc3C(=O)N2Cc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A03 compound treatment 0.306 1.25E-4 0.01 0.311 0.00881 0.8 0.5727 0.7159 1057747 Maybridge3_004579 OC(=O)c1cc2ccc3ccccc3c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A04 compound treatment 0.309 0.00312 0.25 0.311 0.00881 0.8 0.7436 0.8867 1480749 Maybridge3_004580 OC(=O)CC1(CC(=O)Nc2ccc(I)cc2F)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A05 compound treatment 0.412 0.106 8.55 0.41 0.108 9.79 12.9628 0.9977 2077636 Maybridge3_004581 COC(=O)/C=C/1\SC(=NC1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A06 compound treatment 0.301 -0.00488 -0.39 0.305 0.00281 0.26 -0.0971 -0.2073 1459365 Maybridge3_004582 Oc1c(CC(=O)c2cc3ccccc3o2)c(=O)oc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A07 compound treatment 0.302 -0.00388 -0.31 0.304 0.00181 0.16 -0.1043 -0.2957 1626424 Maybridge3_004583 O=C1CC(C(=O)N1Cc2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A08 compound treatment 0.298 -0.00788 -0.63 0.3 -0.00219 -0.2 -0.5888 -0.8861 1083146 Maybridge3_004584 Cc1cccc(NC(C(=O)O)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A09 compound treatment 0.3 -0.00588 -0.47 0.299 -0.00319 -0.29 -0.5391 -0.9722 2077637 Maybridge3_004585 COC(=O)/C=C\1/NCC(O)CNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A10 compound treatment 0.304 -0.00188 -0.15 0.293 -0.00919 -0.83 -0.6965 -0.8218 1264943 Maybridge3_004586 O=C1CC(Sc2ccccn2)C(=O)N1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A11 compound treatment 0.307 0.00112 0.09 0.304 0.00181 0.16 0.1804 0.9605 2077638 Maybridge3_004587 FC(F)(F)c1ccc(/C=C(\C#N)/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A12 compound treatment 0.33 0.0241 1.94 0.331 0.0288 2.62 3.223 0.9893 2077639 Maybridge3_004588 COc1ccc(OC)c(/C=C/2\Sc3ccccc3NC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A13 compound treatment 0.308 0.00212 0.17 0.301 -0.00119 -0.11 0.0448 0.2214 2077640 Maybridge3_004589 OCC1(CO)CSC(=N1)NCc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A14 compound treatment 0.323 0.0171 1.38 0.307 0.00481 0.44 1.284 0.8876 2077641 Maybridge3_004590 CCOC(=O)c1ccc(Nc2scc(C)[n+]2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A15 compound treatment 0.306 1.25E-4 0.01 0.301 -0.00119 -0.11 -0.0691 -0.6383 1493909 Maybridge3_004591 O=C(NCc1csc2ccccc12)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A16 compound treatment 0.305 -8.75E-4 -0.07 0.302 -1.88E-4 -0.02 -0.0619 -0.8534 2077642 Maybridge3_004592 CSC(=N)Nc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A17 compound treatment 0.293 -0.0129 -1.04 0.29 -0.0122 -1.11 -1.5154 -0.9995 1391763 Maybridge3_004593 COc1ccccc1NC(=O)Oc2ccccc2N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A18 compound treatment 0.31 0.00412 0.33 0.311 0.00881 0.8 0.8005 0.9242 1645105 Maybridge3_004594 Clc1ccccc1c2csc(NCC3CCCO3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A19 compound treatment 0.308 0.00212 0.17 0.304 0.00181 0.16 0.2373 0.9998 1244874 Maybridge3_004595 CC1=C(C)CC(C(C1)C(=O)O)C(=O)NCc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A20 compound treatment 0.307 0.00112 0.09 0.306 0.00381 0.35 0.3088 0.8631 1326215 Maybridge3_004596 CSc1cccc(NC(=O)CCC(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A21 compound treatment 0.307 0.00112 0.09 0.301 -0.00119 -0.11 -0.0122 -0.0864 1738235 Maybridge3_004597 CCOC(=O)c1ccc(NC(=O)CC(C)(C)CC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A22 compound treatment 0.309 0.00312 0.25 0.302 -1.88E-4 -0.02 0.1659 0.6578 2077643 Maybridge3_004598 Oc1ccccc1C(=O)Nc2ccc(/N=C/c3cccs3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A23 mock treatment 0.298 -0.00788 -0.63 0.295 -0.00719 -0.65 -0.9097 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 A24 positive control 0.083 -0.223 -17.95 0.085 -0.217 -19.71 -26.6309 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B01 compound treatment 0.329 0.0231 1.86 0.323 0.0208 1.89 2.6526 1.0 1215595 Maybridge3_004599 CN(C)C(=O)Oc1cc2oc(=O)cc(C)c2cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B02 compound treatment 0.331 0.0251 2.02 0.324 0.0218 1.98 2.8307 0.9999 1336123 Maybridge3_004600 Clc1ccc(cc1Cl)N2C(=O)CC3(CCCC3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B03 compound treatment 0.325 0.0191 1.54 0.319 0.0168 1.53 2.1681 1.0 1172685 Maybridge3_004601 CCNc1nc(cs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B04 compound treatment 0.324 0.0181 1.46 0.319 0.0168 1.53 2.1112 0.9998 2077644 Maybridge3_004602 CSc1nnc(o1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B05 compound treatment 0.315 0.00912 0.73 0.32 0.0178 1.62 1.6629 0.9363 1436844 Maybridge3_004603 CC(C)Oc1cc(C)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B06 compound treatment 0.341 0.0351 2.83 0.332 0.0298 2.71 3.9136 0.9998 2077645 Maybridge3_004604 Cc1ccc(Sc2cc(C)nc(n2)c3ccccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B07 compound treatment 0.324 0.0181 1.46 0.314 0.0118 1.07 1.7902 0.9885 2077646 Maybridge3_004605 CC(C)(C)C(=O)Nc1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B08 compound treatment 0.321 0.0151 1.22 0.316 0.0138 1.25 1.7478 0.9999 2077647 Maybridge3_004606 Cc1nc(nc(NCCNc2ccc(cn2)C(F)(F)F)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B09 compound treatment 0.324 0.0181 1.46 0.317 0.0148 1.34 1.9828 0.9992 1688252 Maybridge3_004607 CCOC(=O)C(C)Oc1ccc(cc1)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B10 compound treatment 0.32 0.0141 1.14 0.313 0.0108 0.98 1.4983 0.9973 1421801 Maybridge3_004608 c1sc(nc1c2cccnc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B11 compound treatment 0.32 0.0141 1.14 0.313 0.0108 0.98 1.4983 0.9973 1247050 Maybridge3_004609 Cc1cccc(C)c1NC(=O)CCN2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B12 compound treatment 0.322 0.0161 1.3 0.316 0.0138 1.25 1.8047 0.9998 2077648 Maybridge3_004610 Cc1cc(C)c(C#N)c(Sc2ccccn2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B13 compound treatment 0.321 0.0151 1.22 0.317 0.0148 1.34 1.812 0.9988 1585949 Maybridge3_004611 COc1c(Cl)cccc1c2cn3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B14 compound treatment 0.32 0.0141 1.14 0.317 0.0148 1.34 1.755 0.9965 2077649 Maybridge3_004612 Clc1ccc(N=NN2CCOCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B15 compound treatment 0.321 0.0151 1.22 0.314 0.0118 1.07 1.6194 0.998 1201145 Maybridge3_004613 CC(C)(C)c1ccc(cc1)c2nc(N)nc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B16 compound treatment 0.323 0.0171 1.38 0.314 0.0118 1.07 1.7333 0.9923 2077650 Maybridge3_004614 C=CCSc1nnc([nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B17 compound treatment 0.323 0.0171 1.38 0.319 0.0168 1.53 2.0542 0.9987 1237996 Maybridge3_004615 CNC(=O)Oc1ccccc1OCC(=O)NCc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B18 compound treatment 0.324 0.0181 1.46 0.319 0.0168 1.53 2.1112 0.9998 2077651 Maybridge3_004616 COC(=O)Nc1cc(C)n(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B19 compound treatment 0.32 0.0141 1.14 0.314 0.0118 1.07 1.5625 0.9996 1263058 Maybridge3_004617 COc1ccc(COCC(O)CS(=O)(=O)c2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B20 compound treatment 0.31 0.00412 0.33 0.299 -0.00319 -0.29 0.0303 0.0688 2077652 Maybridge3_004618 CN(C)c1ccc(/C=C/2\C(=O)ON=C2c3cccs3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B21 compound treatment 0.324 0.0181 1.46 0.319 0.0168 1.53 2.1112 0.9998 2077653 Maybridge3_004619 Clc1cccc(Cl)c1CN2CSCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B22 compound treatment 0.31 0.00412 0.33 0.306 0.00381 0.35 0.4796 0.9998 2077654 Maybridge3_004620 CC(C)Sc1cc(C#N)c2cc(Br)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B23 mock treatment 0.308 0.00212 0.17 0.309 0.00681 0.62 0.5583 0.8701 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 B24 positive control 0.084 -0.222 -17.87 0.085 -0.217 -19.71 -26.5739 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C01 compound treatment 0.327 0.0211 1.7 0.318 0.0158 1.44 2.2178 0.9964 1216096 Maybridge3_004621 CCc1c(O)c2ccccc2n(c3ccccc3)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C02 compound treatment 0.326 0.0201 1.62 0.318 0.0158 1.44 2.1609 0.9982 1505505 Maybridge3_004622 CC1=C(C)CC2C(C1)C(=O)N(C2=O)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C03 compound treatment 0.314 0.00812 0.65 0.312 0.00981 0.89 1.0925 0.9885 1436841 Maybridge3_004623 Clc1ccc(CSc2nc3ccccc3c(=O)[nH]2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C04 compound treatment 0.334 0.0281 2.26 0.338 0.0358 3.25 3.9001 0.9844 1349309 Maybridge3_004624 O=C(CSc1nc2ccccc2c(=O)[nH]1)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C05 compound treatment 0.341 0.0351 2.83 0.334 0.0318 2.89 4.0419 0.9999 1570713 Maybridge3_004625 COC(=O)C1=C(C(=C(C(=O)OC)C1=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C06 compound treatment 0.321 0.0151 1.22 0.32 0.0178 1.62 2.0045 0.9902 1472034 Maybridge3_004626 COc1ccc(cc1)c2cc3c(=O)oc4ccccc4c3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C07 compound treatment 0.321 0.0151 1.22 0.316 0.0138 1.25 1.7478 0.9999 2077655 Maybridge3_004627 CS/C(=C(\C#N)/c1ccccn1)/Nc2ccc(C)c(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C08 compound treatment 0.312 0.00612 0.49 0.308 0.00581 0.53 0.7218 0.9994 1083143 Maybridge3_004628 Cc1ccc(NC(C(=O)O)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C09 compound treatment 0.317 0.0111 0.9 0.316 0.0138 1.25 1.52 0.9864 2077656 Maybridge3_004629 COC(=O)/C=C\1/NCCCNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C10 compound treatment 0.322 0.0161 1.3 0.313 0.0108 0.98 1.6122 0.9905 2077657 Maybridge3_004630 CN(C)c1ccc(/C=N/c2ccc3OCOc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C11 compound treatment 0.322 0.0161 1.3 0.313 0.0108 0.98 1.6122 0.9905 1353070 Maybridge3_004631 OC(=O)CSCC(=O)Nc1cccc2CCCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C12 compound treatment 0.36 0.0541 4.36 0.352 0.0498 4.52 6.2791 0.9998 2077658 Maybridge3_004632 O=C/1Nc2ccccc2S\C1=C\c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C13 compound treatment 0.302 -0.00388 -0.31 0.292 -0.0102 -0.92 -0.8745 -0.8961 2077659 Maybridge3_004633 Cc1ccc(/C=C\2/SC(=S)N(CCc3ccc(Cl)cc3)C2=O)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C14 compound treatment 0.314 0.00812 0.65 0.306 0.00381 0.35 0.7073 0.9557 2077660 Maybridge3_004634 CC[N+]1=C(Nc2c(C)cccc2C)SCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C15 compound treatment 0.327 0.0211 1.7 0.319 0.0168 1.53 2.282 0.9985 1224385 Maybridge3_004635 O=C(NCc1csc2ccccc12)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C16 compound treatment 0.31 0.00412 0.33 0.309 0.00681 0.62 0.6721 0.9575 2077661 Maybridge3_004636 Cc1csc(NCc2cccnc2)[n+]1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C17 compound treatment 0.327 0.0211 1.7 0.326 0.0238 2.16 2.7313 0.993 1431111 Maybridge3_004637 OC(=O)CC(CC(=O)Nc1cccc2CCCCc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C18 compound treatment 0.313 0.00712 0.57 0.311 0.00881 0.8 0.9713 0.9867 1679422 Maybridge3_004638 Fc1ccc(cc1)c2csc(NCC3CCCO3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C19 compound treatment 0.328 0.0221 1.78 0.324 0.0218 1.98 2.6599 0.9986 1556559 Maybridge3_004639 COc1cc(OC)cc(c1)N2C(=O)C3CC(=C(C)CC3C2=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C20 compound treatment 0.313 0.00712 0.57 0.307 0.00481 0.44 0.7146 0.9909 2077662 Maybridge3_004640 O/N=C/c1c([nH]c2ccccc12)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C21 compound treatment 0.32 0.0141 1.14 0.313 0.0108 0.98 1.4983 0.9973 1145657 Maybridge3_004641 CC1=C(C)CC2C(C1)C(=O)N(C(Cc3ccccc3)C(=O)O)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C22 compound treatment 0.317 0.0111 0.9 0.31 0.00781 0.71 1.1349 0.9933 2077663 Maybridge3_004642 Oc1ccccc1C(=O)Nc2ccc(/N=C/c3ccco3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C23 mock treatment 0.298 -0.00788 -0.63 0.296 -0.00619 -0.56 -0.8456 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 C24 positive control 0.085 -0.221 -17.79 0.089 -0.213 -19.35 -26.2603 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D01 compound treatment 0.329 0.0231 1.86 0.327 0.0248 2.25 2.9093 0.9955 2077664 Maybridge3_004643 CC1(CO)CS/C(=N\c2ccc(Cl)c(Cl)c2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D02 compound treatment 0.33 0.0241 1.94 0.318 0.0158 1.44 2.3886 0.9889 2077665 Maybridge3_004644 Fc1cc(NC(=O)c2ccco2)c(F)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D03 compound treatment 0.328 0.0221 1.78 0.324 0.0218 1.98 2.6599 0.9986 1665328 Maybridge3_004645 CN(C)C(=O)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D04 compound treatment 0.327 0.0211 1.7 0.317 0.0148 1.34 2.1536 0.9932 2077666 Maybridge3_004646 FC(F)(F)c1ccc(cc1)C2=NCCO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D05 compound treatment 0.331 0.0251 2.02 0.318 0.0158 1.44 2.4456 0.9859 2077667 Maybridge3_004647 Cc1cc(Sc2ccccn2)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D06 compound treatment 0.319 0.0131 1.06 0.306 0.00381 0.35 0.9921 0.892 2077668 Maybridge3_004648 COC(=O)c1cccc(CSC(=S)N2CCCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D07 compound treatment 0.327 0.0211 1.7 0.321 0.0188 1.71 2.4104 1.0 1083960 Maybridge3_004649 Cc1cc(C)c(NC(=O)C(C)(C)C)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D08 compound treatment 0.325 0.0191 1.54 0.322 0.0198 1.8 2.3607 0.997 1188643 Maybridge3_004650 C1CCN(C1)c2nc(ns2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D09 compound treatment 0.323 0.0171 1.38 0.319 0.0168 1.53 2.0542 0.9987 1030449 Maybridge3_004651 CSc1nc(N)cc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D10 compound treatment 0.378 0.0721 5.81 0.369 0.0668 6.06 8.3952 0.9998 2077669 Maybridge3_004652 Cc1nc(nc(SCc2ccccc2)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D11 compound treatment 0.324 0.0181 1.46 0.323 0.0208 1.89 2.3679 0.9919 1151794 Maybridge3_004653 CC1CN(CCC(=O)Nc2c(C)cccc2C)CC(C)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D12 compound treatment 0.325 0.0191 1.54 0.323 0.0208 1.89 2.4248 0.9949 2077670 Maybridge3_004654 CC(C)Oc1nc(C)cc(C)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D13 compound treatment 0.324 0.0181 1.46 0.323 0.0208 1.89 2.3679 0.9919 1656429 Maybridge3_004655 CCc1ccc(NC(=O)c2c(OC)cccc2OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D14 compound treatment 0.326 0.0201 1.62 0.315 0.0128 1.16 1.9683 0.9868 2077671 Maybridge3_004656 CCc1cc(cc(CC)c1NC(=O)C)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D15 compound treatment 0.325 0.0191 1.54 0.316 0.0138 1.25 1.9755 0.9948 2077672 Maybridge3_004657 CCCCc1c(O)nc(SC)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D16 compound treatment 0.32 0.0141 1.14 0.319 0.0168 1.53 1.8834 0.9895 2077673 Maybridge3_004658 CSc1nnc([nH]1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D17 compound treatment 0.318 0.0121 0.98 0.313 0.0108 0.98 1.3844 1.0 1555476 Maybridge3_004659 Cc1ccc(cc1)S(=O)(=O)CC(O)COc2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D18 compound treatment 0.317 0.0111 0.9 0.309 0.00681 0.62 1.0707 0.9836 2077674 Maybridge3_004660 CCOC(=O)c1cc(C)nc(SCC=C)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D19 compound treatment 0.325 0.0191 1.54 0.32 0.0178 1.62 2.2323 0.9997 1120685 Maybridge3_004661 COc1ccc(COCC(O)CS(=O)(=O)c2ccc(C)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D20 compound treatment 0.324 0.0181 1.46 0.326 0.0238 2.16 2.5605 0.9817 2077675 Maybridge3_004662 CCOC(=O)c1cc(nc(SC)c1C#N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D21 compound treatment 0.326 0.0201 1.62 0.316 0.0138 1.25 2.0325 0.992 2077676 Maybridge3_004663 Clc1cc(Cl)cc(CN2CSCC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D22 compound treatment 0.326 0.0201 1.62 0.325 0.0228 2.07 2.6102 0.9926 2077677 Maybridge3_004664 CNc1cc(C#N)c2cc(Br)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D23 mock treatment 0.306 1.25E-4 0.01 0.298 -0.00419 -0.38 -0.2617 -0.6881 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 D24 positive control 0.087 -0.219 -17.63 0.089 -0.213 -19.35 -26.1464 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E01 compound treatment 0.329 0.0231 1.86 0.323 0.0208 1.89 2.6526 1.0 1507548 Maybridge3_004665 C=CCOc1cc(=O)[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E02 compound treatment 0.334 0.0281 2.26 0.32 0.0178 1.62 2.7448 0.9864 1576701 Maybridge3_004666 CCCN1C(C(C(=O)O)c2ccccc2C1=O)c3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E03 compound treatment 0.352 0.0461 3.71 0.342 0.0398 3.61 5.1818 0.9999 1209690 Maybridge3_004667 Cc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E04 compound treatment 0.323 0.0171 1.38 0.317 0.0148 1.34 1.9259 0.9999 1704863 Maybridge3_004668 OC(=O)CC1(CC(=O)Nc2cccnc2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E05 compound treatment 0.313 0.00712 0.57 0.307 0.00481 0.44 0.7146 0.9909 2077678 Maybridge3_004669 Fc1ccc(/C=C(\C#N)/c2c[nH]c3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E06 compound treatment 0.308 0.00212 0.17 0.314 0.0118 1.07 0.8792 0.8097 1178925 Maybridge3_004670 CC(C(=O)c1ccc(C)cc1Cl)c2c(O)c3ccccc3oc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E07 compound treatment 0.319 0.0131 1.06 0.316 0.0138 1.25 1.6339 0.9964 1349371 Maybridge3_004671 CSc1[nH]nc(NC(=O)c2cccs2)c1c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E08 compound treatment 0.326 0.0201 1.62 0.317 0.0148 1.34 2.0967 0.9957 2077679 Maybridge3_004672 CC1=N/C(=C/c2cc(Br)cc(Br)c2O)/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E09 compound treatment 0.336 0.0301 2.43 0.322 0.0198 1.8 2.987 0.9891 2077680 Maybridge3_004673 O=C1CSC(N1CCN2C(SCC2=O)c3cccnc3)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E10 compound treatment 0.325 0.0191 1.54 0.324 0.0218 1.98 2.489 0.9923 2077681 Maybridge3_004674 OC(=O)/C=C/C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E11 compound treatment 0.324 0.0181 1.46 0.319 0.0168 1.53 2.1112 0.9998 2077682 Maybridge3_004675 OC(=O)CC1(CC(=O)Nc2ccc(OC(F)(F)F)cc2)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E12 compound treatment 0.318 0.0121 0.98 0.319 0.0168 1.53 1.7695 0.9767 1028960 Maybridge3_004676 O=C1CCC(=O)N1C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E13 compound treatment 0.322 0.0161 1.3 0.319 0.0168 1.53 1.9973 0.9968 2077683 Maybridge3_004677 Clc1ccc(CCN2C(=O)/C(=C\c3ccccn3)/SC2=S)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E14 compound treatment 0.315 0.00912 0.73 0.306 0.00381 0.35 0.7643 0.941 2077684 Maybridge3_004678 CS/C(=N\C)/Nc1cccc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E15 compound treatment 0.324 0.0181 1.46 0.326 0.0238 2.16 2.5605 0.9817 1693570 Maybridge3_004679 Clc1ccc(cc1)C(=O)NCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E16 compound treatment 0.323 0.0171 1.38 0.317 0.0148 1.34 1.9259 0.9999 2077685 Maybridge3_004680 OC(=O)/C(=C/c1ccc2OCOc2c1)/NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E17 compound treatment 0.326 0.0201 1.62 0.32 0.0178 1.62 2.2892 1.0 1741938 Maybridge3_004681 Ic1ccc(cc1)N2C(=O)CC(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E18 compound treatment 0.358 0.0521 4.2 0.35 0.0478 4.34 6.0369 0.9999 2077686 Maybridge3_004682 COc1cc(/C=C(\C#N)/c2ccccc2)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E19 compound treatment 0.328 0.0221 1.78 0.315 0.0128 1.16 2.0822 0.9786 1703987 Maybridge3_004683 CCOC(=O)c1c(N)sc2Cc3ccccc3-c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E20 compound treatment 0.322 0.0161 1.3 0.316 0.0138 1.25 1.8047 0.9998 2077687 Maybridge3_004684 CCOC(=O)c1ccc(Cl)c(/N=C/c2ccccc2O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E21 compound treatment 0.323 0.0171 1.38 0.315 0.0128 1.16 1.7975 0.9964 2077688 Maybridge3_004685 NCCSc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E22 compound treatment 0.313 0.00712 0.57 0.316 0.0138 1.25 1.2923 0.9372 1676562 Maybridge3_004686 Cc1ccc(cc1)C(=O)OCC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E23 mock treatment 0.301 -0.00488 -0.39 0.298 -0.00419 -0.38 -0.5464 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 E24 positive control 0.089 -0.217 -17.46 0.093 -0.209 -18.99 -25.7758 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F01 compound treatment 0.332 0.0261 2.1 0.327 0.0248 2.25 3.0802 0.9994 2077689 Maybridge3_004687 CSc1nc(OC(=O)N(C)C)cc(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F02 compound treatment 0.449 0.143 11.53 0.447 0.145 13.14 17.4445 0.9979 2077690 Maybridge3_004688 NC(=S)SC(CC(=O)c1ccccc1)c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F03 compound treatment 0.322 0.0161 1.3 0.32 0.0178 1.62 2.0615 0.9941 2077691 Maybridge3_004689 CC[n+]1c(C)csc1Nc2c(C)cc(C)cc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F04 compound treatment 0.333 0.0271 2.18 0.32 0.0178 1.62 2.6878 0.989 1532684 Maybridge3_004690 Cc1onc(c1C2=NCCO2)c3c(F)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F05 compound treatment 0.33 0.0241 1.94 0.328 0.0258 2.34 3.0305 0.9957 2077692 Maybridge3_004691 Cc1cc(C)c(C#N)c(Sc2cc(C)nc(N)n2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F06 compound treatment 0.331 0.0251 2.02 0.333 0.0308 2.8 3.4083 0.9874 1548375 Maybridge3_004692 Cc1ccc(NC(=O)CCS(=O)(=O)Cc2ccccc2)c(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F07 compound treatment 0.323 0.0171 1.38 0.317 0.0148 1.34 1.9259 0.9999 2077693 Maybridge3_004693 Cc1nc(SCC=C)nc(O)c1CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F08 compound treatment 0.333 0.0271 2.18 0.32 0.0178 1.62 2.6878 0.989 2077694 Maybridge3_004694 CN(C)c1nc(ns1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F09 compound treatment 0.337 0.0311 2.51 0.322 0.0198 1.8 3.044 0.9867 2077695 Maybridge3_004695 CCCCc1c(C)nc(SC)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F10 compound treatment 0.348 0.0421 3.39 0.363 0.0608 5.52 6.3019 0.9727 2077696 Maybridge3_004696 FC(F)(F)c1cnc(NCCNc2cnc3ccccc3n2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F11 compound treatment 0.325 0.0191 1.54 0.322 0.0198 1.8 2.3607 0.997 1104173 Maybridge3_004697 CC(Oc1ccc2ccccc2c1I)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F12 compound treatment 0.319 0.0131 1.06 0.306 0.00381 0.35 0.9921 0.892 2077697 Maybridge3_004698 Cc1cc(C)c(C#N)c(SS(=O)(=O)c2nc(C)cc(C)c2C#N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F13 compound treatment 0.319 0.0131 1.06 0.32 0.0178 1.62 1.8906 0.9788 2077698 Maybridge3_004699 Cc1cccc(C)c1NC(=O)/C=C/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F14 compound treatment 0.324 0.0181 1.46 0.32 0.0178 1.62 2.1753 0.9987 2077699 Maybridge3_004700 Cc1onc(c1/C=N/O)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F15 compound treatment 0.355 0.0491 3.96 0.341 0.0388 3.52 5.2884 0.9983 2077700 Maybridge3_004701 CCCc1c(C)nc(nc1OC(=O)N(C)C)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F16 compound treatment 0.325 0.0191 1.54 0.322 0.0198 1.8 2.3607 0.997 2077701 Maybridge3_004702 COc1ccc(OC)c(N=C2SCS2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F17 compound treatment 0.328 0.0221 1.78 0.318 0.0158 1.44 2.2747 0.9943 1464935 Maybridge3_004703 COc1ccc(OC)c(c1)S(=O)(=O)CC(O)COc2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F18 compound treatment 0.334 0.0281 2.26 0.319 0.0168 1.53 2.6806 0.9815 2077702 Maybridge3_004704 CCOC(=O)c1cc(C)nc(c1C#N)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F19 compound treatment 0.297 -0.00888 -0.71 0.309 0.00681 0.62 -0.0681 -0.072 1261530 Maybridge3_004705 OC(CNCc1ccc(Cl)cc1)CSc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F20 compound treatment 0.323 0.0171 1.38 0.321 0.0188 1.71 2.1826 0.9944 2077703 Maybridge3_004706 Cc1cc(O)nc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F21 compound treatment 0.326 0.0201 1.62 0.316 0.0138 1.25 2.0325 0.992 1519666 Maybridge3_004707 OC(COc1ccc(F)cc1)CS(=O)(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F22 compound treatment 0.328 0.0221 1.78 0.314 0.0118 1.07 2.018 0.9705 2077704 Maybridge3_004708 CN(C)C(=O)Oc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F23 mock treatment 0.304 -0.00188 -0.15 0.3 -0.00219 -0.2 -0.2472 -0.9909 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 F24 positive control 0.089 -0.217 -17.46 0.091 -0.211 -19.17 -25.9041 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G01 compound treatment 0.318 0.0121 0.98 0.321 0.0188 1.71 1.8979 0.9648 1120035 Maybridge3_004709 Cn1c(=O)c(Cc2ccccc2)c(OC(=O)c3ccccc3)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G02 compound treatment 0.323 0.0171 1.38 0.318 0.0158 1.44 1.99 0.9998 2077705 Maybridge3_004710 COC(=S)NC(=O)/C=C/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G03 compound treatment 0.336 0.0301 2.43 0.331 0.0288 2.62 3.5647 0.9993 1615301 Maybridge3_004711 Fc1cccc(CSc2nc3ccccc3c(=O)[nH]2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G04 compound treatment 0.429 0.123 9.91 0.425 0.123 11.15 14.8936 0.9983 2077706 Maybridge3_004712 COc1ccc(CCN2C(=O)/C(=C\c3ccccc3C(=O)O)/SC2=S)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G05 compound treatment 0.321 0.0151 1.22 0.313 0.0108 0.98 1.5552 0.9943 1506792 Maybridge3_004713 O=c1[nH]c(=Nc2ccccc2)oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G06 compound treatment 0.324 0.0181 1.46 0.313 0.0108 0.98 1.7261 0.9814 1514263 Maybridge3_004714 Oc1c(CC(=O)c2ccc3OCCOc3c2)c(=O)oc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G07 compound treatment 0.328 0.0221 1.78 0.323 0.0208 1.89 2.5957 0.9996 1326229 Maybridge3_004715 CSc1[nH]nc(NS(=O)(=O)c2ccccc2Cl)c1c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G08 compound treatment 0.328 0.0221 1.78 0.32 0.0178 1.62 2.4031 0.9988 2077707 Maybridge3_004716 CCOc1ccccc1/C=C\2/N=C(C)OC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G09 compound treatment 0.327 0.0211 1.7 0.316 0.0138 1.25 2.0894 0.9887 1099626 Maybridge3_004717 Clc1ccc(cc1)C2SCC(=O)N2CCN3C(SCC3=O)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G10 compound treatment 0.334 0.0281 2.26 0.334 0.0318 2.89 3.6433 0.9928 1569703 Maybridge3_004718 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G11 compound treatment 0.321 0.0151 1.22 0.318 0.0158 1.44 1.8762 0.9967 1280536 Maybridge3_004719 CC(=O)SC1CC(=O)N(C1=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G12 compound treatment 0.322 0.0161 1.3 0.319 0.0168 1.53 1.9973 0.9968 2077708 Maybridge3_004720 CCOC(=O)c1ccc(cc1)N2C(=O)C=C(C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G13 compound treatment 0.342 0.0361 2.91 0.338 0.0358 3.25 4.3556 0.9985 2077709 Maybridge3_004721 Cc1ccc(/N=C/2\NC(=O)C(CC(=O)Nc3ccc(OC(F)(F)F)cc3)S2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G14 compound treatment 0.321 0.0151 1.22 0.316 0.0138 1.25 1.7478 0.9999 2077710 Maybridge3_004722 CN(C)c1ccc(/C=N/c2ccc(C(=O)O)c(O)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G15 compound treatment 0.314 0.00812 0.65 0.308 0.00581 0.53 0.8357 0.9943 1485149 Maybridge3_004723 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G16 compound treatment 0.31 0.00412 0.33 0.316 0.0138 1.25 1.1214 0.8646 2077711 Maybridge3_004724 CSC(=N)Nc1cccc(Cl)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G17 compound treatment 0.327 0.0211 1.7 0.325 0.0228 2.07 2.6671 0.9952 1684112 Maybridge3_004725 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G18 compound treatment 0.322 0.0161 1.3 0.318 0.0158 1.44 1.9331 0.9987 1076472 Maybridge3_004726 COc1cccc(NC(=O)CCC(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G19 compound treatment 0.323 0.0171 1.38 0.32 0.0178 1.62 2.1184 0.9969 2077712 Maybridge3_004727 CSc1cccc(NC(=O)c2cnccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G20 compound treatment 0.349 0.0431 3.47 0.336 0.0338 3.07 4.6258 0.9981 1346759 Maybridge3_004728 COc1cc(c(OC)cc1Cl)n2c(SC)nc3ccccc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G21 compound treatment 0.322 0.0161 1.3 0.319 0.0168 1.53 1.9973 0.9968 2077713 Maybridge3_004729 OC(=O)c1ccccc1CSc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G22 compound treatment 0.311 0.00512 0.41 0.307 0.00481 0.44 0.6007 0.9996 2077714 Maybridge3_004730 COc1ccc(cc1)/C(=C/c2c(Cl)cccc2Cl)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G23 mock treatment 0.306 1.25E-4 0.01 0.299 -0.00319 -0.29 -0.1975 -0.6821 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 G24 positive control 0.091 -0.215 -17.3 0.093 -0.209 -18.99 -25.6619 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H01 compound treatment 0.328 0.0221 1.78 0.328 0.0258 2.34 2.9166 0.9909 2077715 Maybridge3_004731 Oc1nc(nc2ccccc12)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H02 compound treatment 0.329 0.0231 1.86 0.32 0.0178 1.62 2.4601 0.9975 2077716 Maybridge3_004732 S=C1NC(=CC(S1)c2ccsc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H03 compound treatment 0.284 -0.0219 -1.76 0.295 -0.00719 -0.65 -1.7069 -0.9087 2077717 Maybridge3_004733 CC[n+]1ccsc1Nc2c(C)cccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H04 compound treatment 0.326 0.0201 1.62 0.326 0.0238 2.16 2.6743 0.9899 2077718 Maybridge3_004734 FC(F)(F)c1cccc(OC(=O)/C=C/2\OC(=O)c3ccccc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H05 compound treatment 0.321 0.0151 1.22 0.322 0.0198 1.8 2.1329 0.982 1276663 Maybridge3_004735 Cc1cc(NCc2cccnc2)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H06 compound treatment 0.236 -0.0699 -5.63 0.229 -0.0732 -6.64 -8.6763 -0.9966 2077719 Maybridge3_004736 Oc1cc2OCOc2cc1C(N3CCOCC3)c4ccc(cc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H07 compound treatment 0.323 0.0171 1.38 0.312 0.00981 0.89 1.6049 0.9776 1464480 Maybridge3_004737 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H08 compound treatment 0.323 0.0171 1.38 0.318 0.0158 1.44 1.99 0.9998 2077720 Maybridge3_004738 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nsc(n2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H09 compound treatment 0.322 0.0161 1.3 0.321 0.0188 1.71 2.1257 0.9909 1105822 Maybridge3_004739 COc1ccc(OC(C)C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H10 compound treatment 0.322 0.0161 1.3 0.313 0.0108 0.98 1.6122 0.9905 2077721 Maybridge3_004740 CC(C)(C)CC(C)(C)NC(=O)c1c(F)cccc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H11 compound treatment 0.311 0.00512 0.41 0.317 0.0148 1.34 1.2426 0.8835 1321457 Maybridge3_004741 CCc1cccc(CC)c1Nc2ncnc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H12 compound treatment 0.318 0.0121 0.98 0.308 0.00581 0.53 1.0635 0.9583 2077722 Maybridge3_004742 FC(F)(F)c1ccc(Cl)c(N=NN2CCOCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H13 compound treatment 0.322 0.0161 1.3 0.323 0.0208 1.89 2.254 0.9833 2077723 Maybridge3_004743 O=C(NCCc1ccccc1)/C=C/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H14 compound treatment 0.323 0.0171 1.38 0.32 0.0178 1.62 2.1184 0.9969 2077724 Maybridge3_004744 Nc1c(C#N)nnn1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H15 compound treatment 0.32 0.0141 1.14 0.316 0.0138 1.25 1.6908 0.9988 2077725 Maybridge3_004745 CCCc1c(C)nc(nc1O)c2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H16 compound treatment 0.349 0.0431 3.47 0.344 0.0418 3.8 5.1393 0.999 2077726 Maybridge3_004746 COC(=O)c1ccccc1NC(=S)Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H17 compound treatment 0.326 0.0201 1.62 0.323 0.0208 1.89 2.4818 0.9971 2077727 Maybridge3_004747 FC(F)(F)c1cccc(CSC(=S)NC2CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H18 compound treatment 0.323 0.0171 1.38 0.317 0.0148 1.34 1.9259 0.9999 2077728 Maybridge3_004748 Oc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H19 compound treatment 0.32 0.0141 1.14 0.319 0.0168 1.53 1.8834 0.9895 2077729 Maybridge3_004749 Fc1ccc(NC(=O)C(F)(F)Sc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H20 compound treatment 0.325 0.0191 1.54 0.323 0.0208 1.89 2.4248 0.9949 2077730 Maybridge3_004750 CN(C)C(=O)Oc1cc(C)nc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H21 compound treatment 0.323 0.0171 1.38 0.32 0.0178 1.62 2.1184 0.9969 1064062 Maybridge3_004751 OC(=O)c1ccc(C(=O)O)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H22 compound treatment 0.32 0.0141 1.14 0.317 0.0148 1.34 1.755 0.9965 2077731 Maybridge3_004752 Cc1cc(O)c(c2cc[nH]n2)c(=O)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H23 mock treatment 0.307 0.00112 0.09 0.3 -0.00219 -0.2 -0.0763 -0.3498 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 H24 positive control 0.091 -0.215 -17.3 0.093 -0.209 -18.99 -25.6619 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I01 compound treatment 0.319 0.0131 1.06 0.327 0.0248 2.25 2.3399 0.9405 2077732 Maybridge3_004753 Oc1cc(=O)[nH]c(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I02 compound treatment 0.335 0.0291 2.35 0.326 0.0238 2.16 3.1868 0.9992 1712084 Maybridge3_004754 OC(=O)C1C(N(Cc2ccc(F)cc2)C(=O)c3ccccc13)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I03 compound treatment 0.335 0.0291 2.35 0.325 0.0228 2.07 3.1226 0.9981 1537166 Maybridge3_004755 Clc1ccc(SC2CC(=O)N(Cc3ccncc3)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I04 compound treatment 0.33 0.0241 1.94 0.322 0.0198 1.8 2.6454 0.9993 1213993 Maybridge3_004756 COC(=O)c1sccc1NC(=O)C2CC(=C(C)CC2C(=O)O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I05 compound treatment 0.432 0.126 10.16 0.419 0.117 10.6 14.6793 0.9998 2077733 Maybridge3_004757 COc1ccc2C(=O)/C(=N/O)/C=Cc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I06 compound treatment 0.326 0.0201 1.62 0.325 0.0228 2.07 2.6102 0.9926 2077734 Maybridge3_004758 Oc1c(CC(=O)c2ccc(cc2)C(F)(F)F)c(=O)oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I07 compound treatment 0.33 0.0241 1.94 0.318 0.0158 1.44 2.3886 0.9889 2077735 Maybridge3_004759 CSc1[nH]nc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)c1c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I08 compound treatment 0.376 0.0701 5.65 0.372 0.0698 6.34 8.4739 0.9983 1556406 Maybridge3_004760 Nc1ccc(C(=O)O)c2c(cccc12)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I09 compound treatment 0.305 -8.75E-4 -0.07 0.318 0.0158 1.44 0.9651 0.6716 2077736 Maybridge3_004761 CSc1c(c(N)nn1S(=O)(=O)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I10 compound treatment 0.318 0.0121 0.98 0.316 0.0138 1.25 1.577 0.9924 1084584 Maybridge3_004762 CC(N1C(=O)CSC1=S)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I11 compound treatment 0.327 0.0211 1.7 0.325 0.0228 2.07 2.6671 0.9952 1286056 Maybridge3_004763 CC(=O)SC1CC(=O)N(C1=O)c2ccc(F)c(F)c2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I12 compound treatment 0.318 0.0121 0.98 0.32 0.0178 1.62 1.8337 0.9708 2077737 Maybridge3_004764 CCOC(=O)c1ccc(N)c(N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I13 compound treatment 0.326 0.0201 1.62 0.331 0.0288 2.62 2.9953 0.9735 2077738 Maybridge3_004765 CCO/C=C\1/SC(=S)N(CCc2ccc(Cl)cc2)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I14 compound treatment 0.316 0.0101 0.82 0.316 0.0138 1.25 1.4631 0.9783 2077739 Maybridge3_004766 CCC1CS/C(=N\c2ccc(OC)cc2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I15 compound treatment 0.327 0.0211 1.7 0.315 0.0128 1.16 2.0252 0.9828 1532598 Maybridge3_004767 OC(CNCc1csc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I16 compound treatment 0.33 0.0241 1.94 0.315 0.0128 1.16 2.1961 0.9699 1221487 Maybridge3_004768 CN(C)C(=O)Oc1ccc(Br)cc1C(=O)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I17 compound treatment 0.331 0.0251 2.02 0.342 0.0398 3.61 3.986 0.9624 1137600 Maybridge3_004769 O=C1COCC(=O)N1c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I18 compound treatment 0.328 0.0221 1.78 0.319 0.0168 1.53 2.3389 0.997 1563856 Maybridge3_004770 Cc1cccn2cc(nc12)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I19 compound treatment 0.33 0.0241 1.94 0.32 0.0178 1.62 2.517 0.9958 1616219 Maybridge3_004771 O=C(Nc1ccc(Oc2ccccc2)cc1)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I20 compound treatment 0.327 0.0211 1.7 0.328 0.0258 2.34 2.8597 0.9876 1165698 Maybridge3_004772 OC(=O)c1ccccc1Nc2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I21 compound treatment 0.324 0.0181 1.46 0.322 0.0198 1.8 2.3037 0.9946 1306899 Maybridge3_004773 C(N1CCN(Cn2nnc3ccccc23)CC1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I22 compound treatment 0.33 0.0241 1.94 0.321 0.0188 1.71 2.5812 0.9979 1307288 Maybridge3_004774 COc1ccc(cc1)C(=O)OCC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I23 mock treatment 0.31 0.00412 0.33 0.306 0.00381 0.35 0.4796 0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 I24 positive control 0.092 -0.214 -17.22 0.095 -0.207 -18.81 -25.4766 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J01 compound treatment 0.323 0.0171 1.38 0.323 0.0208 1.89 2.311 0.988 2077740 Maybridge3_004775 CC1(C)CS/C(=N\C2CCCCC2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J02 compound treatment 0.333 0.0271 2.18 0.336 0.0338 3.07 3.7148 0.9861 2077741 Maybridge3_004776 Fc1cc(NC(=O)c2ccc(Cl)cc2)c(F)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J03 compound treatment 0.328 0.0221 1.78 0.309 0.00681 0.62 1.6971 0.8999 2077742 Maybridge3_004777 COc1ccc(cc1OC)/C(=C\c2ccc(Cl)cc2)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J04 compound treatment 0.33 0.0241 1.94 0.321 0.0188 1.71 2.5812 0.9979 2077743 Maybridge3_004778 Clc1cc(Cl)cc(OC(=O)/C=C/2\OC(=O)c3ccccc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J05 compound treatment 0.32 0.0141 1.14 0.318 0.0158 1.44 1.8192 0.9934 1708190 Maybridge3_004779 COc1ccc(CCNc2cc(C)nc(N)n2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J06 compound treatment 0.332 0.0261 2.1 0.319 0.0168 1.53 2.5667 0.9876 1474043 Maybridge3_004780 OC1CCCCC1S(=O)(=O)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J07 compound treatment 0.308 0.00212 0.17 0.313 0.0108 0.98 0.815 0.8181 1317323 Maybridge3_004781 CCOC(=O)c1ccc(OC(=O)c2ccc(Cl)cc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J08 compound treatment 0.322 0.0161 1.3 0.322 0.0198 1.8 2.1898 0.9872 1393806 Maybridge3_004782 COc1cc2nc(oc(=O)c2cc1OC)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J09 compound treatment 0.328 0.0221 1.78 0.32 0.0178 1.62 2.4031 0.9988 1054355 Maybridge3_004783 Cc1cc(O)nc(n1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J10 compound treatment 0.332 0.0261 2.1 0.329 0.0268 2.43 3.2085 0.9974 1154490 Maybridge3_004784 COc1cc(cc(OC)c1OC)C(=O)NC(C)(C)CC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J11 compound treatment 0.323 0.0171 1.38 0.319 0.0168 1.53 2.0542 0.9987 1442022 Maybridge3_004785 COc1ccc(OCC(O)CNC(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J12 compound treatment 0.323 0.0171 1.38 0.31 0.00781 0.71 1.4766 0.9522 2077744 Maybridge3_004786 Clc1cccc(N=NN2CCOCC2)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J13 compound treatment 0.319 0.0131 1.06 0.316 0.0138 1.25 1.6339 0.9964 2077745 Maybridge3_004787 Clc1ccc(OC(=O)/C=C/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J14 compound treatment 0.32 0.0141 1.14 0.315 0.0128 1.16 1.6267 0.9999 2077746 Maybridge3_004788 COc1ccc(Br)c(c1)C(=O)Nc2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J15 compound treatment 0.324 0.0181 1.46 0.327 0.0248 2.25 2.6246 0.9779 2077747 Maybridge3_004789 CN(C)C(=O)Oc1cc(C)nc(n1)c2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J16 compound treatment 0.327 0.0211 1.7 0.32 0.0178 1.62 2.3462 0.9997 1350861 Maybridge3_004790 N#Cc1c(cccc1n2ccnc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J17 compound treatment 0.326 0.0201 1.62 0.322 0.0198 1.8 2.4176 0.9987 1433731 Maybridge3_004791 CC(C)N1CC(COc2ccc(Br)cc2)OC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J18 compound treatment 0.322 0.0161 1.3 0.319 0.0168 1.53 1.9973 0.9968 2077748 Maybridge3_004792 Nc1nonc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J19 compound treatment 0.325 0.0191 1.54 0.322 0.0198 1.8 2.3607 0.997 2077749 Maybridge3_004793 Brc1ccc(CSc2nccn2c3cccnc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J20 compound treatment 0.33 0.0241 1.94 0.324 0.0218 1.98 2.7737 1.0 2077750 Maybridge3_004794 CN/C(=N\O)/C(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J21 compound treatment 0.326 0.0201 1.62 0.321 0.0188 1.71 2.3534 0.9997 1388847 Maybridge3_004795 COc1ccc(COCC(O)CS(=O)(=O)Cc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J22 compound treatment 0.32 0.0141 1.14 0.319 0.0168 1.53 1.8834 0.9895 2077751 Maybridge3_004796 COC(=O)CSc1c(Cl)cncc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J23 mock treatment 0.305 -8.75E-4 -0.07 0.299 -0.00319 -0.29 -0.2544 -0.8543 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 J24 positive control 0.092 -0.214 -17.22 0.094 -0.208 -18.9 -25.5408 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K01 compound treatment 0.327 0.0211 1.7 0.325 0.0228 2.07 2.6671 0.9952 2077752 Maybridge3_004797 CCOC(=O)Nc1ccccc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K02 compound treatment 0.325 0.0191 1.54 0.316 0.0138 1.25 1.9755 0.9948 1521071 Maybridge3_004798 CCCSc1ncccc1C(=O)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K03 compound treatment 0.322 0.0161 1.3 0.314 0.0118 1.07 1.6764 0.9955 1675160 Maybridge3_004799 O=C1CSCC(=O)N1Cc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K04 compound treatment 0.331 0.0251 2.02 0.32 0.0178 1.62 2.5739 0.9938 2077753 Maybridge3_004800 NC(=O)C1CCN(CC1)C(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K05 compound treatment 0.332 0.0261 2.1 0.327 0.0248 2.25 3.0802 0.9994 2077754 Maybridge3_004801 CSC(=C(C#N)c1ccccn1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K06 compound treatment 0.315 0.00912 0.73 0.311 0.00881 0.8 1.0852 0.9991 2077755 Maybridge3_004802 COc1ccc(/C=C(\C#N)/c2ccc(C)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K07 compound treatment 0.323 0.0171 1.38 0.315 0.0128 1.16 1.7975 0.9964 2077756 Maybridge3_004803 CC(C)(C)C(=O)CSc1nc(SCC(=O)C(C)(C)C)c2ccccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K08 compound treatment 0.319 0.0131 1.06 0.305 0.00281 0.26 0.9279 0.8534 1278063 Maybridge3_004804 CCOC(=O)CSc1ccc(C(=O)O)c2c(cccc12)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K09 compound treatment 0.31 0.00412 0.33 0.314 0.0118 1.07 0.9931 0.8847 2077757 Maybridge3_004805 Cc1ccc(/C=C(\C#N)/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K10 compound treatment 0.332 0.0261 2.1 0.321 0.0188 1.71 2.6951 0.9946 2077758 Maybridge3_004806 CCO/C(=C\1/SC(=S)NC1=O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K11 compound treatment 0.323 0.0171 1.38 0.325 0.0228 2.07 2.4393 0.9805 1334505 Maybridge3_004807 OC(=O)CC(CC(=O)Nc1ccc(I)cc1F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K12 compound treatment 0.326 0.0201 1.62 0.32 0.0178 1.62 2.2892 1.0 2077759 Maybridge3_004808 CCOC(=O)c1ccc2nc(C)c(C)nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K13 compound treatment 0.327 0.0211 1.7 0.321 0.0188 1.71 2.4104 1.0 1651509 Maybridge3_004809 COc1ccc(cc1)C(=O)NCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K14 compound treatment 0.316 0.0101 0.82 0.317 0.0148 1.34 1.5273 0.9713 2077760 Maybridge3_004810 CC1(C)CS/C(=N\c2ccc(F)cc2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K15 compound treatment 0.319 0.0131 1.06 0.32 0.0178 1.62 1.8906 0.9788 1352090 Maybridge3_004811 OC(=O)c1nccnc1C(=O)Nc2cccc3CCCCc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K16 compound treatment 0.328 0.0221 1.78 0.318 0.0158 1.44 2.2747 0.9943 2077761 Maybridge3_004812 Clc1cc(Br)ccc1/N=C/c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K17 compound treatment 0.324 0.0181 1.46 0.321 0.0188 1.71 2.2395 0.9969 2077762 Maybridge3_004813 CC(C)c1ccc(NC(=O)c2cnccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K18 compound treatment 0.324 0.0181 1.46 0.322 0.0198 1.8 2.3037 0.9946 2077763 Maybridge3_004814 Cc1ccc(/N=C/c2ccc(Cl)cc2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K19 compound treatment 0.315 0.00912 0.73 0.324 0.0218 1.98 1.9196 0.909 2077764 Maybridge3_004815 OC(=O)/C=C/C(=O)NC1CCN(Cc2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K20 compound treatment 0.332 0.0261 2.1 0.319 0.0168 1.53 2.5667 0.9876 2077765 Maybridge3_004816 Oc1ccccc1/C=N/c2ccc(NC(=O)c3ccccc3O)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K21 compound treatment 0.323 0.0171 1.38 0.316 0.0138 1.25 1.8617 0.9989 1610051 Maybridge3_004817 OC(=O)CC1(CC(=O)Nc2ccc3OCOc3c2)CCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K22 compound treatment 0.326 0.0201 1.62 0.319 0.0168 1.53 2.225 0.9995 1289667 Maybridge3_004818 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K23 mock treatment 0.305 -8.75E-4 -0.07 0.302 -1.88E-4 -0.02 -0.0619 -0.8534 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 K24 positive control 0.094 -0.212 -17.06 0.096 -0.206 -18.72 -25.2985 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L01 compound treatment 0.322 0.0161 1.3 0.322 0.0198 1.8 2.1898 0.9872 2077766 Maybridge3_004819 CCOC(=O)c1ccc(NC(=N)SCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L02 compound treatment 0.33 0.0241 1.94 0.319 0.0168 1.53 2.4528 0.9929 2077767 Maybridge3_004820 O=C1N(/C(=N/c2ccccc2)/SC31CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L03 compound treatment 0.337 0.0311 2.51 0.323 0.0208 1.89 3.1081 0.9903 1302497 Maybridge3_004821 COc1cc(cc(OC)c1OC)C(=O)Oc2cc(C)cc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L04 compound treatment 0.33 0.0241 1.94 0.317 0.0148 1.34 2.3244 0.9838 2077768 Maybridge3_004822 CC(=O)Nc1ccc(C#N)c(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L05 compound treatment 0.332 0.0261 2.1 0.329 0.0268 2.43 3.2085 0.9974 1281117 Maybridge3_004823 Clc1ccc(C(=O)Oc2ccc(C#N)cc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L06 compound treatment 0.327 0.0211 1.7 0.324 0.0218 1.98 2.6029 0.9971 2077769 Maybridge3_004824 Cc1nc(c2ccccn2)n3nnnc3c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L07 compound treatment 0.323 0.0171 1.38 0.322 0.0198 1.8 2.2468 0.9914 1671295 Maybridge3_004825 Cc1cc(O)nc(n1)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L08 compound treatment 0.317 0.0111 0.9 0.318 0.0158 1.44 1.6484 0.9743 1181580 Maybridge3_004826 CS(=O)CC(O)(c1ccc(Cl)cc1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L09 compound treatment 0.326 0.0201 1.62 0.322 0.0198 1.8 2.4176 0.9987 1085884 Maybridge3_004827 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L10 compound treatment 0.326 0.0201 1.62 0.319 0.0168 1.53 2.225 0.9995 2077770 Maybridge3_004828 Cc1cc(C)c(C#N)c(Sc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L11 compound treatment 0.314 0.00812 0.65 0.303 8.12E-4 0.07 0.5148 0.7819 1724592 Maybridge3_004829 Clc1ccc(cc1)c2csc(NC(=O)CCN3CCCCC3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L12 compound treatment 0.338 0.0321 2.59 0.334 0.0318 2.89 3.8711 0.9985 2077771 Maybridge3_004830 CSc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L13 compound treatment 0.313 0.00712 0.57 0.299 -0.00319 -0.29 0.2011 0.313 2077772 Maybridge3_004831 CCOC(=O)c1ccc(OC(=O)/C=C/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L14 compound treatment 0.411 0.105 8.47 0.402 0.0998 9.06 12.3924 0.9994 2077773 Maybridge3_004832 Cc1cccc(C)c1NC(=S)SCC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L15 compound treatment 0.323 0.0171 1.38 0.323 0.0208 1.89 2.311 0.988 2077774 Maybridge3_004833 Clc1cccc(NC(=O)/C=C/c2cccs2)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L16 compound treatment 0.32 0.0141 1.14 0.32 0.0178 1.62 1.9476 0.9852 2077775 Maybridge3_004834 Cc1onc(c1/C(=N/O)/N)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L17 compound treatment 0.328 0.0221 1.78 0.327 0.0248 2.25 2.8524 0.9933 1574362 Maybridge3_004835 CC(C)N1CC(COc2ccccc2Cl)OC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L18 compound treatment 0.321 0.0151 1.22 0.326 0.0238 2.16 2.3896 0.9632 1038832 Maybridge3_004836 CCOC(=O)c1c(C)cc(C)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L19 compound treatment 0.323 0.0171 1.38 0.322 0.0198 1.8 2.2468 0.9914 2077776 Maybridge3_004837 CC1(CO)CS/C(=N\c2cccnc2)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L20 compound treatment 0.319 0.0131 1.06 0.325 0.0228 2.07 2.2116 0.9513 2077777 Maybridge3_004838 Nc1c(C#N)nnn1c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L21 compound treatment 0.334 0.0281 2.26 0.322 0.0198 1.8 2.8731 0.9935 2077778 Maybridge3_004839 Clc1ccc(cc1)C(=C2SCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L22 compound treatment 0.32 0.0141 1.14 0.323 0.0208 1.89 2.1401 0.9705 1064612 Maybridge3_004840 COc1c(C)c(C)cc(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L23 mock treatment 0.311 0.00512 0.41 0.306 0.00381 0.35 0.5365 0.9962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 L24 positive control 0.093 -0.213 -17.14 0.096 -0.206 -18.72 -25.3554 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M01 compound treatment 0.332 0.0261 2.1 0.321 0.0188 1.71 2.6951 0.9946 1446539 Maybridge3_004841 O=c1oc(Nc2ccccc2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M02 compound treatment 0.341 0.0351 2.83 0.338 0.0358 3.25 4.2987 0.9976 2077779 Maybridge3_004842 CCCSc1ncccc1C(=O)Nc2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M03 compound treatment 0.317 0.0111 0.9 0.31 0.00781 0.71 1.1349 0.9933 2077780 Maybridge3_004843 FC(F)(F)c1cnc(N2C(=O)CSCC2=O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M04 compound treatment 0.324 0.0181 1.46 0.319 0.0168 1.53 2.1112 0.9998 1119071 Maybridge3_004844 OC(=O)COCc1nc2ccccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M05 compound treatment 0.315 0.00912 0.73 0.322 0.0198 1.8 1.7913 0.922 1463551 Maybridge3_004845 CSc1[nH]nc(NC(=O)c2ccc(cc2)C(C)(C)C)c1c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M06 compound treatment 0.331 0.0251 2.02 0.329 0.0268 2.43 3.1516 0.9958 2077781 Maybridge3_004846 COc1ccc(cc1)/C(=C/c2ccc3OCOc3c2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M07 compound treatment 0.316 0.0101 0.82 0.31 0.00781 0.71 1.078 0.9976 1531010 Maybridge3_004847 Clc1ccc(nc1)N2C(=O)CSCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M08 compound treatment 0.313 0.00712 0.57 0.31 0.00781 0.71 0.9071 0.9945 2077782 Maybridge3_004848 Clc1cccc(c1)/C(=C/c2ccccc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M09 compound treatment 0.327 0.0211 1.7 0.323 0.0208 1.89 2.5387 0.9986 2077783 Maybridge3_004849 N#C/C(=C\c1ccc2OCOc2c1)/c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M10 compound treatment 0.321 0.0151 1.22 0.323 0.0208 1.89 2.1971 0.9775 2077784 Maybridge3_004850 CC(C)c1ccc(/C=C/2\Sc3ccccc3NC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M11 compound treatment 0.315 0.00912 0.73 0.308 0.00581 0.53 0.8927 0.9868 1603595 Maybridge3_004851 CCC1(CC)COC2(OC1)C(=O)Nc3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M12 compound treatment 0.319 0.0131 1.06 0.318 0.0158 1.44 1.7623 0.9887 2077785 Maybridge3_004852 CCCc1nc2ccccc2nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M13 compound treatment 0.315 0.00912 0.73 0.32 0.0178 1.62 1.6629 0.9363 1167424 Maybridge3_004853 O=C(NCc1csc2ccccc12)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M14 compound treatment 0.318 0.0121 0.98 0.313 0.0108 0.98 1.3844 1.0 2077786 Maybridge3_004854 CC1(C)CS/C(=N\c2ccccc2F)/N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M15 compound treatment 0.314 0.00812 0.65 0.317 0.0148 1.34 1.4134 0.9452 1732451 Maybridge3_004855 OC(=O)c1nccnc1C(=O)NCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M16 compound treatment 0.306 1.25E-4 0.01 0.308 0.00581 0.53 0.3802 0.7205 2077787 Maybridge3_004856 CCN(CC)C(=S)Oc1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M17 compound treatment 0.093 -0.213 -17.14 0.093 -0.209 -18.99 -25.548 -0.9987 1915663 Maybridge3_004857 O=C1C=CC(=O)N1c2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M18 compound treatment 0.322 0.0161 1.3 0.314 0.0118 1.07 1.6764 0.9955 2077788 Maybridge3_004858 COc1cc(/C=N/c2ccc(C)c(C)c2)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M19 compound treatment 0.125 -0.181 -14.57 0.125 -0.177 -16.08 -21.672 -0.9988 2077789 Maybridge3_004859 O=C1C=CC(=O)N1C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M20 compound treatment 0.313 0.00712 0.57 0.315 0.0128 1.16 1.2281 0.947 2077790 Maybridge3_004860 COc1ccc(/C=N/c2ccc(NC(=O)c3ccccc3O)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M21 compound treatment 0.323 0.0171 1.38 0.318 0.0158 1.44 1.99 0.9998 1173467 Maybridge3_004861 CSc1cccc(NC(=O)CC2(CC(=O)O)CCCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M22 compound treatment 0.316 0.0101 0.82 0.315 0.0128 1.16 1.3989 0.9849 2077791 Maybridge3_004862 Oc1ccccc1/C=N/c2cccc(NC(=O)c3ccccc3O)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M23 mock treatment 0.301 -0.00488 -0.39 0.3 -0.00219 -0.2 -0.418 -0.9501 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 M24 positive control 0.095 -0.211 -16.98 0.097 -0.205 -18.63 -25.1774 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N01 compound treatment 0.323 0.0171 1.38 0.32 0.0178 1.62 2.1184 0.9969 2077792 Maybridge3_004863 CC(C)c1ccc(/N=C\2/NC(C)(C)CS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N02 compound treatment 0.324 0.0181 1.46 0.321 0.0188 1.71 2.2395 0.9969 2077793 Maybridge3_004864 Cc1ccc(cc1)C(=O)NCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N03 compound treatment 0.329 0.0231 1.86 0.325 0.0228 2.07 2.781 0.9986 1389579 Maybridge3_004865 COc1cc(cc(OC)c1OC)C(=O)N2C(C)CCCC2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N04 compound treatment 0.32 0.0141 1.14 0.314 0.0118 1.07 1.5625 0.9996 1284104 Maybridge3_004866 O=S(=O)(Nc1ccc(cc1)C2=NCCO2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N05 compound treatment 0.317 0.0111 0.9 0.316 0.0138 1.25 1.52 0.9864 2077794 Maybridge3_004867 CSC(=N)Nc1cc(C)c(C)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N06 compound treatment 0.331 0.0251 2.02 0.325 0.0228 2.07 2.8949 0.9999 2077795 Maybridge3_004868 CN(C)c1nc(nc(C)c1Cl)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N07 compound treatment 0.33 0.0241 1.94 0.324 0.0218 1.98 2.7737 1.0 1156935 Maybridge3_004869 CC(Oc1ccc(cc1)C(C)(C)C)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N08 compound treatment 0.338 0.0321 2.59 0.327 0.0248 2.25 3.4218 0.9976 1124791 Maybridge3_004870 Cc1nc(nc(NCc2ccccc2)c1Cl)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N09 compound treatment 0.327 0.0211 1.7 0.315 0.0128 1.16 2.0252 0.9828 1242651 Maybridge3_004871 CCCCc1c(C)nc(nc1O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N10 compound treatment 0.325 0.0191 1.54 0.32 0.0178 1.62 2.2323 0.9997 1398371 Maybridge3_004872 COc1cccc(OC)c1C(=O)NC(C)(C)CC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N11 compound treatment 0.327 0.0211 1.7 0.313 0.0108 0.98 1.8969 0.9658 2077796 Maybridge3_004873 FC(F)(F)c1ccc(Cl)c(NC(=O)CCN2CCOCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N12 compound treatment 0.327 0.0211 1.7 0.329 0.0268 2.43 2.9238 0.9847 2077797 Maybridge3_004874 Cc1cc(C)c(C#N)c(SC(C(=O)Nc2c(F)cccc2F)c3ccccc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N13 compound treatment 0.316 0.0101 0.82 0.312 0.00981 0.89 1.2063 0.999 2077798 Maybridge3_004875 Clc1ccccc1OC(=O)/C=C/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N14 compound treatment 0.332 0.0261 2.1 0.319 0.0168 1.53 2.5667 0.9876 2077799 Maybridge3_004876 Clc1ccc(cc1)C(=O)CSc2nc(n[nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N15 compound treatment 0.299 -0.00688 -0.55 0.295 -0.00719 -0.65 -0.8528 -0.9967 1705140 Maybridge3_004877 Nc1cccc(F)c1CNCC(O)COc2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N16 compound treatment 0.321 0.0151 1.22 0.321 0.0188 1.71 2.0687 0.9863 2077800 Maybridge3_004878 CC(C)(C)c1ccc(cc1)c2noc(CS(=O)(=O)c3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N17 compound treatment 0.316 0.0101 0.82 0.314 0.0118 1.07 1.3347 0.9909 2077801 Maybridge3_004879 Clc1ccccc1N=C2SCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N18 compound treatment 0.32 0.0141 1.14 0.322 0.0198 1.8 2.076 0.9756 2077802 Maybridge3_004880 OC(=O)c1cc(=O)[nH]c2c(Cl)cc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N19 compound treatment 0.322 0.0161 1.3 0.316 0.0138 1.25 1.8047 0.9998 1022817 Maybridge3_004881 OC(C(=O)O)c1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N20 compound treatment 0.376 0.0701 5.65 0.388 0.0858 7.79 9.5009 0.9875 2077803 Maybridge3_004882 CCOC(=O)c1cc(nc(O)c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N21 compound treatment 0.318 0.0121 0.98 0.316 0.0138 1.25 1.577 0.9924 1516478 Maybridge3_004883 COc1ccc(cc1)C(=C2SCCS2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N22 compound treatment 0.329 0.0231 1.86 0.318 0.0158 1.44 2.3317 0.9917 1200223 Maybridge3_004884 Cc1nccc(O)c1OCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N23 mock treatment 0.31 0.00412 0.33 0.306 0.00381 0.35 0.4796 0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 N24 positive control 0.094 -0.212 -17.06 0.095 -0.207 -18.81 -25.3627 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O01 compound treatment 0.344 0.0381 3.07 0.343 0.0408 3.7 4.7904 0.9956 3177792 Maybridge3_004885 COC(=O)c1sc2c(C)cc(Cl)c(C)c2c1C(=O)O.NN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O02 compound treatment 0.334 0.0281 2.26 0.329 0.0268 2.43 3.3224 0.9994 1716542 Maybridge3_004886 COc1ccc(NC(=O)CC2(CC(=O)O)CCCCC2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O03 compound treatment 0.327 0.0211 1.7 0.321 0.0188 1.71 2.4104 1.0 2077805 Maybridge3_004887 Clc1ccc(cc1)C(=O)/C=C\2/NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O04 compound treatment 0.332 0.0261 2.1 0.328 0.0258 2.34 3.1444 0.9986 2077806 Maybridge3_004888 CCOC(=O)CN1CCN(CC1)c2ccc(cc2N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O05 compound treatment 0.341 0.0351 2.83 0.336 0.0338 3.07 4.1703 0.9992 2077807 Maybridge3_004889 CS/C(=C(/C#N)\c1ccccn1)/Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O06 compound treatment 0.327 0.0211 1.7 0.327 0.0248 2.25 2.7955 0.9904 1083137 Maybridge3_004890 OC(=O)C(Nc1ccccc1C(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O07 compound treatment 0.33 0.0241 1.94 0.318 0.0158 1.44 2.3886 0.9889 2077808 Maybridge3_004891 COC(=O)/C=C\1/NCCNC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O08 compound treatment 0.319 0.0131 1.06 0.323 0.0208 1.89 2.0832 0.9623 2077809 Maybridge3_004892 CN(C)c1ccc(/C=C\2/N=C(OC2=O)c3ccc(Cl)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O09 compound treatment 0.328 0.0221 1.78 0.326 0.0238 2.16 2.7882 0.9954 2077810 Maybridge3_004893 N#C/C(=C\c1cccnc1)/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O10 compound treatment 0.386 0.0801 6.45 0.382 0.0798 7.24 9.6852 0.9983 2077811 Maybridge3_004894 O=C/1Nc2ccccc2S\C1=C/c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O11 compound treatment 0.325 0.0191 1.54 0.324 0.0218 1.98 2.489 0.9923 2077812 Maybridge3_004895 C=CCOc1cccc(/C=C\2/SC(=S)N(CCc3ccccc3)C2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O12 compound treatment 0.324 0.0181 1.46 0.316 0.0138 1.25 1.9186 0.9971 2077813 Maybridge3_004896 CS/C(=N\c1ccc(C)cc1C)/NCc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O13 compound treatment 0.319 0.0131 1.06 0.312 0.00981 0.89 1.3772 0.9964 1431421 Maybridge3_004897 O=C(NCc1csc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O14 compound treatment 0.324 0.0181 1.46 0.314 0.0118 1.07 1.7902 0.9885 2077814 Maybridge3_004898 Cc1cccc(C)c1/N=C\2/NC(C)(C)CS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O15 compound treatment 0.329 0.0231 1.86 0.331 0.0288 2.62 3.1661 0.9861 1294681 Maybridge3_004899 Cc1ccc(NC(=O)CC(CC(=O)O)c2ccccc2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O16 compound treatment 0.318 0.0121 0.98 0.315 0.0128 1.16 1.5128 0.9962 2077815 Maybridge3_004900 Clc1ccc(cc1)/C(=C/c2ccco2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O17 compound treatment 0.329 0.0231 1.86 0.322 0.0198 1.8 2.5884 0.9998 1146675 Maybridge3_004901 OC(=O)c1nccnc1C(=O)NC(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O18 compound treatment 0.329 0.0231 1.86 0.328 0.0258 2.34 2.9735 0.9935 2077816 Maybridge3_004902 Oc1ccccc1/C=N/c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O19 compound treatment 0.323 0.0171 1.38 0.318 0.0158 1.44 1.99 0.9998 1617828 Maybridge3_004903 OC(=O)COCC(=O)NC1CCN(Cc2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O20 compound treatment 0.322 0.0161 1.3 0.325 0.0228 2.07 2.3824 0.9747 2077817 Maybridge3_004904 Oc1ccccc1C(=O)Nc2ccc(/N=C/c3cccnc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O21 compound treatment 0.324 0.0181 1.46 0.325 0.0228 2.07 2.4963 0.9853 2077818 Maybridge3_004905 Cc1cc(NC(=O)CC(CC(=O)O)c2ccc(cc2)C(F)(F)F)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O22 compound treatment 0.331 0.0251 2.02 0.327 0.0248 2.25 3.0232 0.9986 1193598 Maybridge3_004906 COc1cccc(OC)c1C(=O)OCC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O23 mock treatment 0.313 0.00712 0.57 0.312 0.00981 0.89 1.0355 0.9774 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 O24 positive control 0.095 -0.211 -16.98 0.096 -0.206 -18.72 -25.2416 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P01 compound treatment 0.322 0.0161 1.3 0.323 0.0208 1.89 2.254 0.9833 2077819 Maybridge3_004907 C[n+]1c(NC2CCCCC2)scc1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P02 compound treatment 0.352 0.0461 3.71 0.337 0.0348 3.16 4.8608 0.9968 1236772 Maybridge3_004908 N(c1nc(cs1)c2ccccc2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P03 compound treatment 0.328 0.0221 1.78 0.317 0.0148 1.34 2.2106 0.9904 2077820 Maybridge3_004909 CS/C(=N\C)/Nc1ccc(C)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P04 compound treatment 0.325 0.0191 1.54 0.32 0.0178 1.62 2.2323 0.9997 2077821 Maybridge3_004910 Cc1cc(Oc2cc(Cl)cc(Cl)c2)nc(n1)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P05 compound treatment 0.32 0.0141 1.14 0.326 0.0238 2.16 2.3327 0.955 2077822 Maybridge3_004911 CSc1nnnn1c2c(C)cc(C)cc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P06 compound treatment 0.334 0.0281 2.26 0.336 0.0338 3.07 3.7717 0.9888 2077823 Maybridge3_004912 Cc1nc(nc(NCCNc2ncccc2C(F)(F)F)c1Cl)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P07 compound treatment 0.344 0.0381 3.07 0.337 0.0348 3.16 4.4053 0.9999 1125776 Maybridge3_004913 CC(Oc1ccc(I)cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P08 compound treatment 0.317 0.0111 0.9 0.313 0.0108 0.98 1.3275 0.999 1206668 Maybridge3_004914 C(Nc1nc(ns1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P09 compound treatment 0.324 0.0181 1.46 0.321 0.0188 1.71 2.2395 0.9969 1402859 Maybridge3_004915 Cc1cccc(C)c1NC(=O)CCN2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P10 compound treatment 0.318 0.0121 0.98 0.321 0.0188 1.71 1.8979 0.9648 2077824 Maybridge3_004916 CCOC(=O)CSc1nc(C)cc(C)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P11 compound treatment 0.317 0.0111 0.9 0.32 0.0178 1.62 1.7768 0.9612 1084805 Maybridge3_004917 CCCCc1c(C)nc(N)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P12 compound treatment 0.323 0.0171 1.38 0.322 0.0198 1.8 2.2468 0.9914 1361233 Maybridge3_004918 Cc1cc(C)c(C#N)c(SC(C(=O)NC(C)(C)C)c2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P13 compound treatment 0.338 0.0321 2.59 0.335 0.0328 2.98 3.9353 0.9975 2077825 Maybridge3_004919 Ic1ccc(OC(=O)/C=C/c2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P14 compound treatment 0.313 0.00712 0.57 0.316 0.0138 1.25 1.2923 0.9372 1471150 Maybridge3_004920 Oc1ccc(c2csc3nc(nn23)c4ccccc4)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P15 compound treatment 0.322 0.0161 1.3 0.318 0.0158 1.44 1.9331 0.9987 1210521 Maybridge3_004921 Oc1ccccc1OCC(=O)NCc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P16 compound treatment 0.316 0.0101 0.82 0.317 0.0148 1.34 1.5273 0.9713 2077826 Maybridge3_004922 CC(C)(C)c1ccc(cc1)c2noc(CSc3ccccn3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P17 compound treatment 0.319 0.0131 1.06 0.319 0.0168 1.53 1.8265 0.9839 2077827 Maybridge3_004923 Clc1ccc(N=C2SCCS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P18 compound treatment 0.346 0.0401 3.23 0.333 0.0308 2.8 4.2625 0.9974 1519868 Maybridge3_004924 Cc1cc2c(O)nnc(N)c2c(Sc3ccc(Cl)cc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P19 compound treatment 0.325 0.0191 1.54 0.32 0.0178 1.62 2.2323 0.9997 1397309 Maybridge3_004925 CC1CC2(CC(=O)N(C2=O)c3ccc(Cl)cc3)CC(C)(C)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P20 compound treatment 0.32 0.0141 1.14 0.317 0.0148 1.34 1.755 0.9965 1094103 Maybridge3_004926 OC(Cc1cccnc1)(c2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P21 compound treatment 0.325 0.0191 1.54 0.32 0.0178 1.62 2.2323 0.9997 1303836 Maybridge3_004927 Clc1cc(Cl)cc(c1)N2C(=O)CC3(CCCC3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P22 compound treatment 0.324 0.0181 1.46 0.32 0.0178 1.62 2.1753 0.9987 1633565 Maybridge3_004928 Cc1nccc(O)c1OCC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P23 mock treatment 0.311 0.00512 0.41 0.309 0.00681 0.62 0.7291 0.9807 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1444 P24 positive control 0.096 -0.21 -16.9 0.099 -0.203 -18.44 -24.9921 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A01 compound treatment 0.307 4.37E-4 0.04 0.308 -0.00319 -0.29 -0.1797 -0.6165 2077828 Maybridge3_004929 CN(C)C(=O)Oc1noc2ccc(C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A02 compound treatment 0.308 0.00144 0.12 0.315 0.00381 0.35 0.3266 0.8949 1668297 Maybridge3_004930 Oc1nc(nc2CCSCc12)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A03 compound treatment 0.307 4.37E-4 0.04 0.306 -0.00519 -0.47 -0.308 -0.6524 1313901 Maybridge3_004931 CC(Oc1c(C)nccc1O)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A04 compound treatment 0.307 4.37E-4 0.04 0.31 -0.00119 -0.11 -0.0513 -0.4524 2077829 Maybridge3_004932 CNc1nc2cc(Cl)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A05 compound treatment 0.306 -5.63E-4 -0.05 0.308 -0.00319 -0.29 -0.2366 -0.808 2077830 Maybridge3_004933 CC(C)(C)c1ccc(NC(=O)C2CC2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A06 compound treatment 0.313 0.00644 0.52 0.322 0.0108 0.98 1.0606 0.9555 2077831 Maybridge3_004934 Cn1cc(Cl)c(/C=C(\C#N)/S(=O)(=O)c2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A07 compound treatment 0.303 -0.00356 -0.29 0.307 -0.00419 -0.38 -0.4716 -0.9904 2077832 Maybridge3_004935 Oc1ncc(Oc2ccc(Cl)cc2Cl)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A08 compound treatment 0.315 0.00844 0.68 0.312 8.12E-4 0.07 0.5326 0.7793 2077833 Maybridge3_004936 Cn1cc(Cl)c(n1)c2nc(cs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A09 compound treatment 0.299 -0.00756 -0.61 0.308 -0.00319 -0.29 -0.6352 -0.9421 2077834 Maybridge3_004937 CS/C(=N\C#N)/NC1(CC2CC3CC(C2)C1)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A10 compound treatment 0.299 -0.00756 -0.61 0.304 -0.00719 -0.65 -0.8919 -0.9994 2077835 Maybridge3_004938 CNC(=O)OC(C)(C)C#Cc1cncnc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A11 compound treatment 0.3 -0.00656 -0.53 0.31 -0.00119 -0.11 -0.4499 -0.8342 1072389 Maybridge3_004939 COC(=O)c1cc(OC)nc(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A12 compound treatment 0.305 -0.00156 -0.13 0.309 -0.00219 -0.2 -0.2294 -0.9758 2077836 Maybridge3_004940 Cn1nc(cc1C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A13 compound treatment 0.303 -0.00356 -0.29 0.307 -0.00419 -0.38 -0.4716 -0.9904 2077837 Maybridge3_004941 Oc1ccc(Oc2c(Cl)cncc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A14 compound treatment 0.324 0.0174 1.4 0.334 0.0228 2.07 2.4571 0.9821 2077838 Maybridge3_004942 CCN(C(=O)c1cnccc1C(F)(F)F)c2cccc(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A15 compound treatment 0.306 -5.63E-4 -0.05 0.317 0.00581 0.53 0.341 0.644 1625339 Maybridge3_004943 Nc1nc(O)nc(n1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A16 compound treatment 0.307 4.37E-4 0.04 0.317 0.00581 0.53 0.398 0.7526 2077839 Maybridge3_004944 Cn1nc(O)c2c(ccnc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A17 compound treatment 0.306 -5.63E-4 -0.05 0.313 0.00181 0.16 0.0843 0.494 2077840 Maybridge3_004945 Cc1cc(NCc2ccccc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A18 compound treatment 0.305 -0.00156 -0.13 0.31 -0.00119 -0.11 -0.1652 -0.997 2077841 Maybridge3_004946 Cc1ccc(cc1)c2nnnn2c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A19 compound treatment 0.309 0.00244 0.2 0.312 8.12E-4 0.07 0.1909 0.9106 2077842 Maybridge3_004947 CC(C)(C)C(=O)OCC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A20 compound treatment 0.321 0.0144 1.16 0.326 0.0148 1.34 1.7728 0.9974 2077843 Maybridge3_004948 CCN(C(=O)c1c(OC)nccc1C(F)(F)F)c2c(C)cccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A21 compound treatment 0.303 -0.00356 -0.29 0.307 -0.00419 -0.38 -0.4716 -0.9904 1028520 Maybridge3_004949 CCSc1nc(O)cc(n1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A22 compound treatment 0.307 4.37E-4 0.04 0.307 -0.00419 -0.38 -0.2439 -0.6388 2077844 Maybridge3_004950 CN(C(=O)c1cnc(O)cc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A23 mock treatment 0.292 -0.0146 -1.17 0.298 -0.0132 -1.2 -1.6756 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 A24 positive control 0.084 -0.223 -17.92 0.083 -0.228 -20.71 -27.3191 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B01 compound treatment 0.322 0.0154 1.24 0.331 0.0198 1.8 2.1507 0.9837 2077845 Maybridge3_004951 CCOC(=O)c1c(C)n[nH]c1SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B02 compound treatment 0.326 0.0194 1.57 0.334 0.0228 2.07 2.571 0.9905 1631011 Maybridge3_004952 Cc1ccc2ncnc(Oc3ncccc3NC(=O)C(C)(C)C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B03 compound treatment 0.318 0.0114 0.92 0.325 0.0138 1.25 1.5378 0.9885 2077846 Maybridge3_004953 NC(=O)c1c(O)nccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B04 compound treatment 0.28 -0.0266 -2.14 0.283 -0.0282 -2.56 -3.3217 -0.996 2077847 Maybridge3_004954 Nc1cccnc1Sc2nc3cccnc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B05 compound treatment 0.312 0.00544 0.44 0.317 0.00581 0.53 0.6827 0.9957 2077848 Maybridge3_004955 CCC(=O)Nc1cc(cnc1OC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B06 compound treatment 0.315 0.00844 0.68 0.323 0.0118 1.07 1.2386 0.9758 1690665 Maybridge3_004956 Oc1cc(=O)oc2c3ccccc3n(c4ccccc4)c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B07 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 2077849 Maybridge3_004957 FC(F)(F)c1cccc(c1)n2c(noc2=O)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B08 compound treatment 0.317 0.0104 0.84 0.322 0.0108 0.98 1.2883 0.997 2077850 Maybridge3_004958 CC(NCc1ccccc1O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B09 compound treatment 0.33 0.0234 1.89 0.332 0.0208 1.89 2.6704 1.0 2077851 Maybridge3_004959 Nc1cnc(Oc2c(Cl)cccc2Cl)c(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B10 compound treatment 0.315 0.00844 0.68 0.33 0.0188 1.71 1.6879 0.9184 1019826 Maybridge3_004960 O=C1CCCN1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B11 compound treatment 0.319 0.0124 1.0 0.324 0.0128 1.16 1.5306 0.9972 2077852 Maybridge3_004961 CC(C)(C)c1ccc(cc1)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B12 compound treatment 0.319 0.0124 1.0 0.324 0.0128 1.16 1.5306 0.9972 2077853 Maybridge3_004962 CSc1nc(c(C#N)c(=O)[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B13 compound treatment 0.315 0.00844 0.68 0.327 0.0158 1.44 1.4954 0.9417 2077854 Maybridge3_004963 Clc1ccc(cc1)c2csc(n2)c3[nH]ncc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B14 compound treatment 0.315 0.00844 0.68 0.32 0.00881 0.8 1.0461 0.9967 2077855 Maybridge3_004964 COc1c2CCCc2c(C)cc1/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B15 compound treatment 0.318 0.0114 0.92 0.326 0.0148 1.34 1.602 0.983 1031000 Maybridge3_004965 O=c1cc(oc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B16 compound treatment 0.322 0.0154 1.24 0.329 0.0178 1.62 2.0223 0.9916 2077856 Maybridge3_004966 COc1ccccc1c2nnc(SC)n2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B17 compound treatment 0.309 0.00244 0.2 0.318 0.00681 0.62 0.5761 0.8879 2077857 Maybridge3_004967 Cn1c(=O)c(C#N)c(c2cccs2)n3cnnc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B18 compound treatment 0.316 0.00944 0.76 0.325 0.0138 1.25 1.4239 0.9712 1193356 Maybridge3_004968 CCNc1nc2ccc(Cl)cc2nc1NCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B19 compound treatment 0.355 0.0484 3.9 0.359 0.0478 4.34 5.8269 0.9986 2077858 Maybridge3_004969 COc1ccc(OC)c(Sc2ccc3nnc(c4ccccc4)n3n2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B20 compound treatment 0.337 0.0304 2.45 0.34 0.0288 2.62 3.5825 0.9995 2077859 Maybridge3_004970 C(N1CCCCC1)c2nnc(o2)c3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B21 compound treatment 0.324 0.0174 1.4 0.331 0.0198 1.8 2.2646 0.9925 1372286 Maybridge3_004971 COC(CSc1nc2cccc(F)c2c(=O)n1c3ccc(C)c(C)c3)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B22 compound treatment 0.313 0.00644 0.52 0.316 0.00481 0.44 0.6754 0.9964 1255927 Maybridge3_004972 O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B23 mock treatment 0.307 4.37E-4 0.04 0.313 0.00181 0.16 0.1412 0.8395 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 B24 positive control 0.085 -0.222 -17.84 0.084 -0.227 -20.62 -27.198 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C01 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 1454544 Maybridge3_004973 CC(C)(C)NC(=O)Oc1noc2cc(Cl)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C02 compound treatment 0.325 0.0184 1.48 0.325 0.0138 1.25 1.9364 0.9965 2077860 Maybridge3_004974 Clc1ccc(/N=C/c2ccn(n2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C03 compound treatment 0.302 -0.00456 -0.37 0.302 -0.00919 -0.83 -0.8495 -0.9322 1261257 Maybridge3_004975 Cc1onc(c1C(=O)Oc2noc3ccccc23)c4c(Cl)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C04 compound treatment 0.309 0.00244 0.2 0.319 0.00781 0.71 0.6402 0.8701 1283591 Maybridge3_004976 CCNc1nc2cc(Cl)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C05 compound treatment 0.321 0.0144 1.16 0.321 0.00981 0.89 1.4519 0.9913 1234934 Maybridge3_004977 Nc1nnc(O)c2cc(nc(O)c12)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C06 compound treatment 0.325 0.0184 1.48 0.331 0.0198 1.8 2.3215 0.9955 2077861 Maybridge3_004978 FC(F)(F)c1ccncc1c2nnc(o2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C07 compound treatment 0.333 0.0264 2.13 0.323 0.0118 1.07 2.2636 0.9496 2077862 Maybridge3_004979 Clc1ccc(cc1)C2=CSC(=C(C#N)C#N)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C08 compound treatment 0.318 0.0114 0.92 0.332 0.0208 1.89 1.9871 0.9455 2077863 Maybridge3_004980 CC(C)NC(=O)OCc1noc(n1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C09 compound treatment 0.32 0.0134 1.08 0.316 0.00481 0.44 1.074 0.9204 2077864 Maybridge3_004981 COC(=O)c1snc(c1C(=O)OC)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C10 compound treatment 0.323 0.0164 1.32 0.339 0.0278 2.52 2.7211 0.9546 2077865 Maybridge3_004982 Cc1nc(c2noc(n2)c3cccc(Cl)c3)c(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C11 compound treatment 0.314 0.00744 0.6 0.313 0.00181 0.16 0.5398 0.8692 2077866 Maybridge3_004983 CN(C)N/C(=N\O)/c1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C12 compound treatment 0.315 0.00844 0.68 0.326 0.0148 1.34 1.4312 0.95 2077867 Maybridge3_004984 Clc1ccc(cc1)c2cc(on2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C13 compound treatment 0.321 0.0144 1.16 0.314 0.00281 0.26 1.0026 0.8423 1565017 Maybridge3_004985 COc1nc(N)nc(n1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C14 compound treatment 0.315 0.00844 0.68 0.323 0.0118 1.07 1.2386 0.9758 1138067 Maybridge3_004986 COC(=O)C(CC(=O)c1cccs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C15 compound treatment 0.31 0.00344 0.28 0.32 0.00881 0.8 0.7614 0.8995 1584990 Maybridge3_004987 COc1nc(N)nc(n1)C2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C16 compound treatment 0.357 0.0504 4.06 0.357 0.0458 4.16 5.8124 0.9999 2077868 Maybridge3_004988 CCN(Cc1ccc(OC)cc1OC)C(=O)c2cnc(OC)cc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C17 compound treatment 0.312 0.00544 0.44 0.321 0.00981 0.89 0.9394 0.9465 2077869 Maybridge3_004989 OCc1nc(cs1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C18 compound treatment 0.322 0.0154 1.24 0.326 0.0148 1.34 1.8298 0.9992 2077870 Maybridge3_004990 Cc1cccc(C)c1n2nnnc2c3cnccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C19 compound treatment 0.314 0.00744 0.6 0.314 0.00281 0.26 0.604 0.9277 1691304 Maybridge3_004991 CC(C)(O)C(=O)OCC(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C20 compound treatment 0.323 0.0164 1.32 0.331 0.0198 1.8 2.2076 0.9886 2077871 Maybridge3_004992 COC(=O)c1cncc(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C21 compound treatment 0.313 0.00644 0.52 0.318 0.00681 0.62 0.8038 0.9962 2077872 Maybridge3_004993 CSc1nc(C)nc(c1C#N)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C22 compound treatment 0.317 0.0104 0.84 0.323 0.0118 1.07 1.3525 0.9927 2077873 Maybridge3_004994 CC1(OCCO1)C2(C)OCCO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C23 mock treatment 0.295 -0.0116 -0.93 0.302 -0.00919 -0.83 -1.2481 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 C24 positive control 0.085 -0.222 -17.84 0.085 -0.226 -20.53 -27.1338 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D01 compound treatment 0.335 0.0284 2.29 0.342 0.0308 2.8 3.597 0.9951 2077874 Maybridge3_004995 FC(F)(F)COc1ncccc1C(=O)NCc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D02 compound treatment 0.326 0.0194 1.57 0.331 0.0198 1.8 2.3785 0.9976 2077875 Maybridge3_004996 C1CC1n2nnc3cccnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D03 compound treatment 0.324 0.0174 1.4 0.329 0.0178 1.62 2.1362 0.9975 2077876 Maybridge3_004997 CC(C)C(=O)NCc1c(C)cc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D04 compound treatment 0.323 0.0164 1.32 0.328 0.0168 1.53 2.0151 0.9975 1333573 Maybridge3_004998 CCOC(=O)c1cc(=O)c2ccc(OC(=O)c3cccs3)cc2o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D05 compound treatment 0.329 0.0224 1.81 0.329 0.0178 1.62 2.4209 0.9985 1519109 Maybridge3_004999 Clc1ccc(c2noc(=O)n2c3cccnc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D06 compound treatment 0.324 0.0174 1.4 0.325 0.0138 1.25 1.8795 0.9984 2077877 Maybridge3_005000 CCCCc1ccc(N/C=N/O)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D07 compound treatment 0.32 0.0134 1.08 0.325 0.0138 1.25 1.6517 0.9973 1380506 Maybridge3_005001 O=c1onc(c2cccnc2)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D08 compound treatment 0.319 0.0124 1.0 0.325 0.0138 1.25 1.5948 0.9938 2077878 Maybridge3_005002 CC(C)CC(NCc1ccccc1O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D09 compound treatment 0.322 0.0154 1.24 0.328 0.0168 1.53 1.9581 0.9948 2077879 Maybridge3_005003 Nc1ccc(OCC(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D10 compound treatment 0.321 0.0144 1.16 0.333 0.0218 1.98 2.2221 0.9678 1303968 Maybridge3_005004 CCCCc1cc(C)c2[nH]c(=O)cc(C)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D11 compound treatment 0.316 0.00944 0.76 0.326 0.0148 1.34 1.4881 0.9635 2077880 Maybridge3_005005 Cc1coc(=O)n1c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D12 compound treatment 0.319 0.0124 1.0 0.325 0.0138 1.25 1.5948 0.9938 1539028 Maybridge3_005006 COc1ccc(N(C)CC(=O)O)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D13 compound treatment 0.314 0.00744 0.6 0.325 0.0138 1.25 1.3101 0.9428 1409985 Maybridge3_005007 CSc1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D14 compound treatment 0.326 0.0194 1.57 0.326 0.0148 1.34 2.0575 0.9971 2077881 Maybridge3_005008 CC1Sc2ccc(cc2NC1=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D15 compound treatment 0.335 0.0284 2.29 0.334 0.0228 2.07 3.0835 0.9987 2077882 Maybridge3_005009 Oc1ccccc1c2cc(n[nH]2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D16 compound treatment 0.322 0.0154 1.24 0.33 0.0188 1.71 2.0865 0.9878 1138183 Maybridge3_005010 O=C(Nc1nc-2c(Cc3ccccc23)s1)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D17 compound treatment 0.323 0.0164 1.32 0.334 0.0228 2.07 2.4002 0.9766 1196135 Maybridge3_005011 CCOC(=O)c1cnn2c1[nH]c(=O)c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D18 compound treatment 0.345 0.0384 3.1 0.346 0.0348 3.16 4.4231 0.9999 1725366 Maybridge3_005012 CN(C(=O)COc1cc(C)c2C(=O)CC(C)(C)Oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D19 compound treatment 0.324 0.0174 1.4 0.336 0.0248 2.25 2.5855 0.9741 2077883 Maybridge3_005013 CCOC(=O)CSc1ccc2nnc(c3ccccc3)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D20 compound treatment 0.324 0.0174 1.4 0.33 0.0188 1.71 2.2004 0.9953 2077884 Maybridge3_005014 CN1CC2CCC1CC(C2)NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D21 compound treatment 0.395 0.0884 7.12 0.403 0.0918 8.33 10.9287 0.9969 2077885 Maybridge3_005015 Cc1cc(C=C2C(=O)CC(C)(C)CC2=O)oc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D22 compound treatment 0.334 0.0274 2.21 0.339 0.0278 2.52 3.3475 0.9978 1318276 Maybridge3_005016 COc1ccccc1C2CCN(CC2)C(=O)c3ccc(N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D23 mock treatment 0.307 4.37E-4 0.04 0.311 -1.88E-4 -0.02 0.0129 0.3291 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 D24 positive control 0.087 -0.22 -17.68 0.088 -0.223 -20.26 -26.8274 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E01 compound treatment 0.315 0.00844 0.68 0.32 0.00881 0.8 1.0461 0.9967 1601560 Maybridge3_005017 CCCNC(=O)Oc1noc2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E02 compound treatment 0.327 0.0204 1.65 0.334 0.0228 2.07 2.628 0.9935 2077886 Maybridge3_005018 Oc1nc(nc2CCSCc12)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E03 compound treatment 0.322 0.0154 1.24 0.329 0.0178 1.62 2.0223 0.9916 2077887 Maybridge3_005019 O/N=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E04 compound treatment 0.342 0.0354 2.85 0.347 0.0358 3.25 4.3165 0.9979 2077888 Maybridge3_005020 CN(C(=O)c1cnccc1C(F)(F)F)c2nc3cc(Cl)ccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E05 compound treatment 0.318 0.0114 0.92 0.325 0.0138 1.25 1.5378 0.9885 2077889 Maybridge3_005021 Cc1nc(nc(O)c1Cl)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E06 compound treatment 0.33 0.0234 1.89 0.336 0.0248 2.25 2.9271 0.9961 2077890 Maybridge3_005022 FC(F)(F)c1ccncc1c2ncc(o2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E07 compound treatment 0.321 0.0144 1.16 0.327 0.0158 1.44 1.837 0.9945 2077891 Maybridge3_005023 CS/C(=N\C#N)/NCc1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E08 compound treatment 0.324 0.0174 1.4 0.326 0.0148 1.34 1.9436 0.9998 2077892 Maybridge3_005024 CCOc1cccc(NC(=O)c2nc(C)oc2C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E09 compound treatment 0.318 0.0114 0.92 0.329 0.0178 1.62 1.7946 0.9644 2077893 Maybridge3_005025 CSc1nnc([nH]1)C2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E10 compound treatment 0.333 0.0264 2.13 0.34 0.0288 2.62 3.3547 0.9948 2077894 Maybridge3_005026 CCN(C(=O)c1cnc(OC)cc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E11 compound treatment 0.32 0.0134 1.08 0.321 0.00981 0.89 1.395 0.9953 1287188 Maybridge3_005027 Oc1nsc(Nc2ccc(Cl)cc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E12 compound treatment 0.312 0.00544 0.44 0.321 0.00981 0.89 0.9394 0.9465 2077895 Maybridge3_005028 COc1ccc(CNC(=O)c2cnc(OC)cc2C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E13 compound treatment 0.317 0.0104 0.84 0.324 0.0128 1.16 1.4167 0.9873 2077896 Maybridge3_005029 CN(C)c1nc(C)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E14 compound treatment 0.331 0.0244 1.97 0.334 0.0228 2.07 2.8557 0.9997 2077897 Maybridge3_005030 CCSc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E15 compound treatment 0.32 0.0134 1.08 0.327 0.0158 1.44 1.7801 0.9903 1922922 Maybridge3_005031 OCc1nc(cs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E16 compound treatment 0.318 0.0114 0.92 0.326 0.0148 1.34 1.602 0.983 2077898 Maybridge3_005032 NC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E17 compound treatment 0.333 0.0264 2.13 0.329 0.0178 1.62 2.6487 0.9908 2077899 Maybridge3_005033 CSc1nc(N)nc(n1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E18 compound treatment 0.321 0.0144 1.16 0.327 0.0158 1.44 1.837 0.9945 2077900 Maybridge3_005034 OC(=O)c1c(O)nccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E19 compound treatment 0.316 0.00944 0.76 0.32 0.00881 0.8 1.103 0.9997 2077901 Maybridge3_005035 Clc1ccc(/C=N/Cc2cccnc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E20 compound treatment 0.349 0.0424 3.42 0.353 0.0418 3.8 5.1002 0.9986 2077902 Maybridge3_005036 CCN(Cc1cc(OC)cc(OC)c1)C(=O)c2c(OC)nccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E21 compound treatment 0.339 0.0324 2.61 0.345 0.0338 3.07 4.0173 0.9968 2077903 Maybridge3_005037 Fc1ccc(SC(=O)Nc2ccccc2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E22 compound treatment 0.319 0.0124 1.0 0.32 0.00881 0.8 1.2738 0.9938 2077904 Maybridge3_005038 FC(F)(F)c1cc(Cl)c2nnc(CNC(=O)c3ccccc3)n2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E23 mock treatment 0.302 -0.00456 -0.37 0.306 -0.00519 -0.47 -0.5928 -0.9925 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 E24 positive control 0.09 -0.217 -17.44 0.087 -0.224 -20.35 -26.7207 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F01 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 2077905 Maybridge3_005039 CN(C)C(=O)c1ccc(OCC(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F02 compound treatment 0.323 0.0164 1.32 0.329 0.0178 1.62 2.0793 0.9951 3177834 Maybridge3_005040 CC1CN(Cc2ccccc2)CCN1.OC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F03 compound treatment 0.326 0.0194 1.57 0.336 0.0248 2.25 2.6994 0.9842 2077907 Maybridge3_005041 CCSc1nccc(c1C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F04 compound treatment 0.322 0.0154 1.24 0.324 0.0128 1.16 1.7014 0.9994 1568121 Maybridge3_005042 Clc1ccc2c(ccnc2c1)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F05 compound treatment 0.324 0.0174 1.4 0.329 0.0178 1.62 2.1362 0.9975 1705288 Maybridge3_005043 Clc1cccc(c2noc(=O)n2c3cccnc3)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F06 compound treatment 0.316 0.00944 0.76 0.327 0.0158 1.44 1.5523 0.9558 2077908 Maybridge3_005044 O=C1/C(=C/c2ccccc2)/Cc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F07 compound treatment 0.326 0.0194 1.57 0.323 0.0118 1.07 1.865 0.983 1434016 Maybridge3_005045 COc1ccc(cc1)c2noc(=O)n2c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F08 compound treatment 0.332 0.0254 2.05 0.33 0.0188 1.71 2.6559 0.9959 2077909 Maybridge3_005046 CSCCC(NCc1ccccc1O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F09 compound treatment 0.325 0.0184 1.48 0.339 0.0278 2.52 2.835 0.968 2077910 Maybridge3_005047 Nc1ccc(Sc2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F10 compound treatment 0.314 0.00744 0.6 0.329 0.0178 1.62 1.5668 0.9087 2077911 Maybridge3_005048 CC1=N/C(=C/c2ccc(C)cc2)/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F11 compound treatment 0.35 0.0434 3.5 0.359 0.0478 4.34 5.5422 0.9943 2077912 Maybridge3_005049 COc1cccc(OC)c1CN(C)C(=O)c2cnc(OC(C)C)cc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F12 compound treatment 0.337 0.0304 2.45 0.331 0.0198 1.8 3.0048 0.9884 2077913 Maybridge3_005050 Cc1c(sc2ccccc12)C(=O)CSc3ncccc3C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F13 compound treatment 0.318 0.0114 0.92 0.326 0.0148 1.34 1.602 0.983 1382721 Maybridge3_005051 CN(C)c1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F14 compound treatment 0.324 0.0174 1.4 0.339 0.0278 2.52 2.7781 0.9617 1010987 Maybridge3_005052 O=C1C(c2ccccc2N1Cc3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F15 compound treatment 0.326 0.0194 1.57 0.338 0.0268 2.43 2.8277 0.9772 2077914 Maybridge3_005053 Cc1cc(C)c(c2cc([nH]n2)c3ccccc3Cl)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F16 compound treatment 0.328 0.0214 1.73 0.333 0.0218 1.98 2.6207 0.9977 2077915 Maybridge3_005054 CCOC(=O)c1ccccc1NC(=O)CSc2ncccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F17 compound treatment 0.324 0.0174 1.4 0.327 0.0158 1.44 2.0078 0.9999 1507326 Maybridge3_005055 CCOC(=O)c1cnn2c1nc(N)c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F18 compound treatment 0.327 0.0204 1.65 0.33 0.0188 1.71 2.3712 0.9998 1373326 Maybridge3_005056 Cc1cc(OCC(=O)O)cc2OC(C)(C)CC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F19 compound treatment 0.322 0.0154 1.24 0.328 0.0168 1.53 1.9581 0.9948 2077916 Maybridge3_005057 OCCSc1ccc2nnc(c3ccccc3)n2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F20 compound treatment 0.365 0.0584 4.71 0.366 0.0548 4.98 6.8456 0.9996 1479693 Maybridge3_005058 COc1cc(ccc1O)c2onc3ccc(Cl)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F21 compound treatment 0.324 0.0174 1.4 0.33 0.0188 1.71 2.2004 0.9953 2077917 Maybridge3_005059 CSc1nc2cc(Cl)c(Cl)cc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F22 compound treatment 0.322 0.0154 1.24 0.332 0.0208 1.89 2.2149 0.9794 2077918 Maybridge3_005060 COC(=O)C1(C)Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F23 mock treatment 0.303 -0.00356 -0.29 0.31 -0.00119 -0.11 -0.2791 -0.9106 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 F24 positive control 0.089 -0.218 -17.52 0.09 -0.221 -20.08 -26.5851 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G01 compound treatment 0.316 0.00944 0.76 0.32 0.00881 0.8 1.103 0.9997 1172405 Maybridge3_005061 CCN(CC)OC(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G02 compound treatment 0.319 0.0124 1.0 0.325 0.0138 1.25 1.5948 0.9938 2077919 Maybridge3_005062 Cn1cc(Cl)c(/C=N/O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G03 compound treatment 0.315 0.00844 0.68 0.328 0.0168 1.53 1.5595 0.9336 1049120 Maybridge3_005063 CC(=O)Nc1ccc(cc1Br)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G04 compound treatment 0.32 0.0134 1.08 0.328 0.0168 1.53 1.8443 0.9858 2077920 Maybridge3_005064 CC(C)OC(=O)Nc1cnccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G05 compound treatment 0.322 0.0154 1.24 0.331 0.0198 1.8 2.1507 0.9837 2077921 Maybridge3_005065 Cc1nc(nc(O)c1Cl)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G06 compound treatment 0.32 0.0134 1.08 0.335 0.0238 2.16 2.2935 0.9488 2077922 Maybridge3_005066 Cn1cc(Cl)c(/C=C(\C#N)/S(=O)(=O)C(C)(C)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G07 compound treatment 0.322 0.0154 1.24 0.325 0.0138 1.25 1.7656 1.0 2077923 Maybridge3_005067 CS/C(=N/C#N)/NCc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G08 compound treatment 0.345 0.0384 3.1 0.344 0.0328 2.98 4.2947 0.9998 2077924 Maybridge3_005068 Cc1nc(c2ncc(o2)c3ccccc3)c(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G09 compound treatment 0.317 0.0104 0.84 0.33 0.0188 1.71 1.8018 0.9467 2077925 Maybridge3_005069 Nc1n[nH]c(NCc2cccnc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G10 compound treatment 0.34 0.0334 2.69 0.353 0.0418 3.8 4.5877 0.9859 2077926 Maybridge3_005070 CCOc1cc(c(cn1)C(=O)N(CC)c2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G11 compound treatment 0.325 0.0184 1.48 0.347 0.0358 3.25 3.3485 0.937 2077927 Maybridge3_005071 COCc1cc(O)n(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G12 compound treatment 0.326 0.0194 1.57 0.34 0.0288 2.62 2.9561 0.9699 2077928 Maybridge3_005072 COc1cc(c(cn1)C(=O)NCc2cccc(Cl)c2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G13 compound treatment 0.319 0.0124 1.0 0.334 0.0228 2.07 2.1724 0.9444 2077929 Maybridge3_005073 CSc1nc(N)nc(n1)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G14 compound treatment 0.313 0.00644 0.52 0.349 0.0378 3.43 2.7936 0.8048 2077930 Maybridge3_005074 CNc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G15 compound treatment 0.329 0.0224 1.81 0.353 0.0418 3.8 3.9613 0.9424 2077931 Maybridge3_005075 CC(C)(C)C(=O)OCc1noc(n1)c2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G16 compound treatment 0.326 0.0194 1.57 0.35 0.0388 3.52 3.598 0.9333 2077932 Maybridge3_005076 FC(F)(F)c1ccncc1c2nnnn2c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G17 compound treatment 0.323 0.0164 1.32 0.34 0.0288 2.62 2.7853 0.9502 1538786 Maybridge3_005077 Clc1ccc(CNCc2cccnc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G18 compound treatment 0.332 0.0254 2.05 0.345 0.0338 3.07 3.6187 0.9807 2077933 Maybridge3_005078 COc1nccc(c1C(=O)Nc2ccc(Cl)cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G19 compound treatment 0.323 0.0164 1.32 0.318 0.00681 0.62 1.3732 0.9399 2077934 Maybridge3_005079 OCc1nc(cs1)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G20 compound treatment 0.322 0.0154 1.24 0.329 0.0178 1.62 2.0223 0.9916 1451821 Maybridge3_005080 O=C(Oc1ccc(CC#N)cc1)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G21 compound treatment 0.436 0.129 10.42 0.442 0.131 11.87 15.7665 0.9979 2077935 Maybridge3_005081 CNC(=S)Sc1ccc(F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G22 compound treatment 0.322 0.0154 1.24 0.323 0.0118 1.07 1.6372 0.9973 2077936 Maybridge3_005082 OC(=O)c1ccc(OCC(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G23 mock treatment 0.306 -5.63E-4 -0.05 0.312 8.12E-4 0.07 0.0201 0.2325 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 G24 positive control 0.092 -0.215 -17.28 0.089 -0.222 -20.17 -26.4785 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H01 compound treatment 0.323 0.0164 1.32 0.327 0.0158 1.44 1.9509 0.9992 2077937 Maybridge3_005083 CCC(=O)NCc1ccc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H02 compound treatment 0.326 0.0194 1.57 0.336 0.0248 2.25 2.6994 0.9842 2077938 Maybridge3_005084 CSc1nc2cccnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H03 compound treatment 0.321 0.0144 1.16 0.34 0.0288 2.62 2.6714 0.9334 2077939 Maybridge3_005085 CCC(=O)Nc1cnc(OC)c(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H04 compound treatment 0.325 0.0184 1.48 0.375 0.0638 5.79 5.1457 0.8605 1428554 Maybridge3_005086 CC(=CC(=O)Nc1nnc(Sc2ccnc3cc(Cl)ccc23)s1)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H05 compound treatment 0.322 0.0154 1.24 0.385 0.0738 6.7 5.6167 0.8242 2077940 Maybridge3_005087 COc1ccccc1N/C(=N\O)/c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H06 compound treatment 0.325 0.0184 1.48 0.357 0.0458 4.16 3.9903 0.9037 2077941 Maybridge3_005088 COC(=O)c1cccc(CSc2ncccc2C(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H07 compound treatment 0.326 0.0194 1.57 0.383 0.0718 6.52 5.7161 0.8527 1679611 Maybridge3_005089 Fc1cccc(F)c1c2noc(=O)n2c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H08 compound treatment 0.32 0.0134 1.08 0.381 0.0698 6.34 5.2461 0.816 1394439 Maybridge3_005090 COc1ccc(OC)c(c2cc[nH]n2)c1OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H09 compound treatment 0.314 0.00744 0.6 0.367 0.0558 5.07 4.0058 0.7852 2077942 Maybridge3_005091 Nc1cnc(Sc2ccccc2)c(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H10 compound treatment 0.323 0.0164 1.32 0.355 0.0438 3.98 3.7481 0.8942 2077943 Maybridge3_005092 COC(=O)c1cc(Br)c(Br)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H11 compound treatment 0.332 0.0254 2.05 0.378 0.0668 6.06 5.7368 0.8962 2077944 Maybridge3_005093 COc1cccc(OC)c1CN(C)C(=O)c2c(OC)nccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H12 compound treatment 0.343 0.0364 2.93 0.377 0.0658 5.97 6.299 0.9464 1367935 Maybridge3_005094 CC(=O)OC(C(=O)N(Cc1ccccc1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H13 compound treatment 0.335 0.0284 2.29 0.348 0.0368 3.34 3.9821 0.983 1194404 Maybridge3_005095 COc1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H14 compound treatment 0.342 0.0354 2.85 0.371 0.0598 5.43 5.8569 0.9549 1471887 Maybridge3_005096 CCOC(=O)c1c(C)n(C2CC2)c3ccc(O)cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H15 compound treatment 0.327 0.0204 1.65 0.354 0.0428 3.89 3.9117 0.9269 2077945 Maybridge3_005097 Oc1ccccc1C(=O)CC(=O)c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H16 compound treatment 0.335 0.0284 2.29 0.371 0.0598 5.43 5.4583 0.9263 1603605 Maybridge3_005098 Cc1cc(no1)C(=O)Nc2nc-3c(Cc4ccccc34)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H17 compound treatment 0.343 0.0364 2.93 0.357 0.0458 4.16 5.0153 0.9854 2077946 Maybridge3_005099 FC(F)(F)c1ccc(cc1)c2nnc3ccc(NC4CC4)nn23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H18 compound treatment 0.381 0.0744 5.99 0.387 0.0758 6.88 9.1046 0.9976 1736812 Maybridge3_005100 O=C(Nc1cccc(c1)C(=O)c2ccccc2)c3cccnc3Oc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H19 compound treatment 0.372 0.0654 5.27 0.392 0.0808 7.34 8.913 0.9868 2077947 Maybridge3_005101 Clc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H20 compound treatment 0.337 0.0304 2.45 0.363 0.0518 4.7 5.0587 0.9539 2077948 Maybridge3_005102 C(N1CCOCC1)c2nnc(o2)c3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H21 compound treatment 0.336 0.0294 2.37 0.352 0.0408 3.7 4.2957 0.9767 1475594 Maybridge3_005103 Cc1ccc(CNc2ccc3nnc(c4ccccc4)n3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H22 compound treatment 0.323 0.0164 1.32 0.339 0.0278 2.52 2.7211 0.9546 2077949 Maybridge3_005104 CC(C)Oc1ccccc1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H23 mock treatment 0.309 0.00244 0.2 0.317 0.00581 0.53 0.5119 0.9093 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 H24 positive control 0.093 -0.214 -17.2 0.092 -0.219 -19.9 -26.229 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I01 compound treatment 0.331 0.0244 1.97 0.336 0.0248 2.25 2.9841 0.9977 2077950 Maybridge3_005105 CCN(CC)OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I02 compound treatment 0.326 0.0194 1.57 0.332 0.0208 1.89 2.4426 0.9956 2077951 Maybridge3_005106 CC(C)Oc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I03 compound treatment 0.332 0.0254 2.05 0.336 0.0248 2.25 3.041 0.9989 1510007 Maybridge3_005107 CC(=O)Nc1ccc(cc1C#N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I04 compound treatment 0.321 0.0144 1.16 0.329 0.0178 1.62 1.9654 0.9869 2077952 Maybridge3_005108 CSc1nc(nc(N)c1C#N)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I05 compound treatment 0.324 0.0174 1.4 0.328 0.0168 1.53 2.072 0.9991 1669143 Maybridge3_005109 CC(C)(C)c1ccc(NC(=O)c2ccco2)c(N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I06 compound treatment 0.308 0.00144 0.12 0.289 -0.0222 -2.01 -1.3423 -0.6654 2077953 Maybridge3_005110 FC(F)(F)c1ccncc1c2nc(no2)c3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I07 compound treatment 0.337 0.0304 2.45 0.325 0.0138 1.25 2.6197 0.9515 1486142 Maybridge3_005111 CC(=O)Nc1cccc(c1)c2cc(no2)c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I08 compound treatment 0.326 0.0194 1.57 0.331 0.0198 1.8 2.3785 0.9976 2077954 Maybridge3_005112 OCc1noc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I09 compound treatment 0.327 0.0204 1.65 0.338 0.0268 2.43 2.8847 0.9818 1123605 Maybridge3_005113 CNc1nc(ns1)C2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I10 compound treatment 0.341 0.0344 2.77 0.34 0.0288 2.62 3.8102 0.9996 2077955 Maybridge3_005114 COc1cc(c(cn1)C(=O)N(C)c2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I11 compound treatment 0.317 0.0104 0.84 0.326 0.0148 1.34 1.5451 0.9744 2077956 Maybridge3_005115 Clc1ccc(Cn2ccnc2C(=O)c3ccccc3Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I12 compound treatment 0.332 0.0254 2.05 0.332 0.0208 1.89 2.7843 0.9992 2077957 Maybridge3_005116 COc1cc(c(cn1)C(=O)Nc2cccc(C)c2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I13 compound treatment 0.322 0.0154 1.24 0.324 0.0128 1.16 1.7014 0.9994 2077958 Maybridge3_005117 CCSc1nc(C)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I14 compound treatment 0.325 0.0184 1.48 0.325 0.0138 1.25 1.9364 0.9965 2077959 Maybridge3_005118 CC(C)Nc1cc(c(cn1)C(=O)Nc2c(C)cccc2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I15 compound treatment 0.322 0.0154 1.24 0.332 0.0208 1.89 2.2149 0.9794 1088402 Maybridge3_005119 COC(=O)c1ccc(nc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I16 compound treatment 0.333 0.0264 2.13 0.342 0.0308 2.8 3.4831 0.9909 2077960 Maybridge3_005120 CCc1ccccc1n2nnnc2c3cnccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I17 compound treatment 0.333 0.0264 2.13 0.335 0.0238 2.16 3.0338 1.0 1639568 Maybridge3_005121 CC(C)(C)C(=O)N(Cc1cccs1)Cc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I18 compound treatment 0.333 0.0264 2.13 0.325 0.0138 1.25 2.3919 0.9681 2077961 Maybridge3_005122 COc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I19 compound treatment 0.366 0.0594 4.79 0.359 0.0478 4.34 6.4533 0.9988 1119880 Maybridge3_005123 CC(C)(C)C(=O)N(Cc1cccnc1)Cc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I20 compound treatment 0.331 0.0244 1.97 0.334 0.0228 2.07 2.8557 0.9997 2077962 Maybridge3_005124 FC(F)(F)c1ccncc1C(=O)Oc2ccc(CC#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I21 compound treatment 0.33 0.0234 1.89 0.335 0.0238 2.16 2.863 0.9977 1092463 Maybridge3_005125 Nc1ccc(cc1)n2ccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I22 compound treatment 0.328 0.0214 1.73 0.331 0.0198 1.8 2.4923 0.9998 2077963 Maybridge3_005126 NC(=O)c1cccnc1OCC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I23 mock treatment 0.312 0.00544 0.44 0.315 0.00381 0.35 0.5543 0.9932 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 I24 positive control 0.093 -0.214 -17.2 0.092 -0.219 -19.9 -26.229 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J01 compound treatment 0.324 0.0174 1.4 0.328 0.0168 1.53 2.072 0.9991 2077964 Maybridge3_005127 CC(C)C(=O)NCc1ccc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J02 compound treatment 0.323 0.0164 1.32 0.331 0.0198 1.8 2.2076 0.9886 1607458 Maybridge3_005128 Nc1cccc(F)c1c2nc(n[nH]2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J03 compound treatment 0.34 0.0334 2.69 0.348 0.0368 3.34 4.2668 0.9943 2077965 Maybridge3_005129 Fc1ccc(NC(=O)c2c(Oc3ccccc3)nccc2C(F)(F)F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J04 compound treatment 0.329 0.0224 1.81 0.33 0.0188 1.71 2.4851 0.9996 1278612 Maybridge3_005130 Clc1ccc2c(Sc3nnc(NC(=O)C4CC4)s3)ccnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J05 compound treatment 0.32 0.0134 1.08 0.324 0.0128 1.16 1.5875 0.9994 2077966 Maybridge3_005131 Cc1ccccc1N/C(=N\O)/c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J06 compound treatment 0.326 0.0194 1.57 0.341 0.0298 2.71 3.0203 0.9661 2077967 Maybridge3_005132 CSc1c(C#N)c(N)nc(SCc2ccc(C)cc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J07 compound treatment 0.3 -0.00656 -0.53 0.318 0.00681 0.62 0.0636 0.0782 2077968 Maybridge3_005133 FC(F)(F)c1ccccc1c2noc(=O)n2c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J08 compound treatment 0.312 0.00544 0.44 0.32 0.00881 0.8 0.8752 0.9598 1058359 Maybridge3_005134 COc1ccc2ccccc2c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J09 compound treatment 0.316 0.00944 0.76 0.327 0.0158 1.44 1.5523 0.9558 1395393 Maybridge3_005135 CCOC(=O)c1noc(Oc2ccc(Cl)cc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J10 compound treatment 0.318 0.0114 0.92 0.321 0.00981 0.89 1.2811 0.9999 2077969 Maybridge3_005136 CS(=O)(=O)c1ncc(Cl)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J11 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 2077970 Maybridge3_005137 COc1ccccc1n2c(C)coc2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J12 compound treatment 0.327 0.0204 1.65 0.33 0.0188 1.71 2.3712 0.9998 2077971 Maybridge3_005138 Cc1cc(ccc1NC(=O)c2cccs2)c3nnc(o3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J13 compound treatment 0.318 0.0114 0.92 0.32 0.00881 0.8 1.2169 0.9975 1719948 Maybridge3_005139 CSc1ccncc1C(=O)Nc2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J14 compound treatment 0.323 0.0164 1.32 0.322 0.0108 0.98 1.63 0.9892 1123701 Maybridge3_005140 OC1(Cc2ccncc2)C(=O)Nc3ccc(F)cc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J15 compound treatment 0.326 0.0194 1.57 0.323 0.0118 1.07 1.865 0.983 2077972 Maybridge3_005141 Clc1ccc(cc1)C(=O)CC(C(=O)c2cccnc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J16 compound treatment 0.343 0.0364 2.93 0.344 0.0328 2.98 4.1809 1.0 1421742 Maybridge3_005142 CCOC(=O)c1csc(NC(=O)CSc2cc(Cl)ccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J17 compound treatment 0.331 0.0244 1.97 0.34 0.0288 2.62 3.2408 0.9902 1524229 Maybridge3_005143 OCCSc1nc2n(ncc2c(=O)[nH]1)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J18 compound treatment 0.356 0.0494 3.98 0.348 0.0368 3.34 5.1778 0.9962 2077973 Maybridge3_005144 CN(C(=O)CSc1nc(C2CCCCC2)c(C#N)c(=O)[nH]1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J19 compound treatment 0.369 0.0624 5.03 0.366 0.0548 4.98 7.0734 1.0 2077974 Maybridge3_005145 FC(F)(F)c1cccc(Oc2ccc3nnc(c4ccccc4)n3n2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J20 compound treatment 0.311 0.00444 0.36 0.315 0.00381 0.35 0.4974 0.9999 1509284 Maybridge3_005146 CNC(C)CN1c2ccccc2Sc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J21 compound treatment 0.325 0.0184 1.48 0.327 0.0158 1.44 2.0648 0.9999 2077975 Maybridge3_005147 Fc1ccc(COc2ncnc3cc(Cl)ccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J22 compound treatment 0.322 0.0154 1.24 0.327 0.0158 1.44 1.894 0.9974 1344604 Maybridge3_005148 C1Cc2ccccc2C(N1)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J23 mock treatment 0.308 0.00144 0.12 0.312 8.12E-4 0.07 0.134 0.9763 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 J24 positive control 0.095 -0.212 -17.04 0.092 -0.219 -19.9 -26.1151 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K01 compound treatment 0.312 0.00544 0.44 0.318 0.00681 0.62 0.7469 0.9857 2077976 Maybridge3_005149 CCNC(=O)Oc1noc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K02 compound treatment 0.324 0.0174 1.4 0.328 0.0168 1.53 2.072 0.9991 2077977 Maybridge3_005150 CN(C(=O)c1cnccc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K03 compound treatment 0.32 0.0134 1.08 0.324 0.0128 1.16 1.5875 0.9994 1171341 Maybridge3_005151 CC(=O)Nc1ccc(cc1N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K04 compound treatment 0.348 0.0414 3.34 0.349 0.0378 3.43 4.7865 0.9999 2077978 Maybridge3_005152 CSc1nc(nc(N)c1C#N)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K05 compound treatment 0.321 0.0144 1.16 0.322 0.0108 0.98 1.5161 0.9965 1425442 Maybridge3_005153 NC(=O)c1ccc(OCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K06 compound treatment 0.326 0.0194 1.57 0.33 0.0188 1.71 2.3143 0.9991 2077979 Maybridge3_005154 FC(F)(F)c1ccncc1c2noc(n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K07 compound treatment 0.317 0.0104 0.84 0.324 0.0128 1.16 1.4167 0.9873 2077980 Maybridge3_005155 CCOC(=O)c1cc(no1)c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K08 compound treatment 0.323 0.0164 1.32 0.331 0.0198 1.8 2.2076 0.9886 2077981 Maybridge3_005156 Clc1ccc(NC(=O)OCc2noc(n2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K09 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 2077982 Maybridge3_005157 Nc1n[nH]c(NCc2ccco2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K10 compound treatment 0.327 0.0204 1.65 0.334 0.0228 2.07 2.628 0.9935 2077983 Maybridge3_005158 CCOc1cc(c(cn1)C(=O)NCc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K11 compound treatment 0.323 0.0164 1.32 0.328 0.0168 1.53 2.0151 0.9975 2077984 Maybridge3_005159 CCOC(=O)/C(=C/1\SCC(C)(O)N1c2c(F)cccc2F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K12 compound treatment 0.334 0.0274 2.21 0.337 0.0258 2.34 3.2191 0.9996 2077985 Maybridge3_005160 CSc1cc(c(cn1)C(=O)Nc2cccc(C)c2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K13 compound treatment 0.323 0.0164 1.32 0.324 0.0128 1.16 1.7583 0.9979 1444169 Maybridge3_005161 CSc1nc(N)nc(n1)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K14 compound treatment 0.343 0.0364 2.93 0.348 0.0368 3.34 4.4376 0.9979 2077986 Maybridge3_005162 CCN(C(=O)c1cnc(SC)cc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K15 compound treatment 0.322 0.0154 1.24 0.33 0.0188 1.71 2.0865 0.9878 2077987 Maybridge3_005163 Cc1ccc(cc1)c2csc(CO)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K16 compound treatment 0.329 0.0224 1.81 0.332 0.0208 1.89 2.6135 0.9998 2077988 Maybridge3_005164 FC(F)(F)c1ccc(cc1)n2nnnc2c3cnccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K17 compound treatment 0.329 0.0224 1.81 0.331 0.0198 1.8 2.5493 1.0 2077989 Maybridge3_005165 CC(=O)OCC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K18 compound treatment 0.337 0.0304 2.45 0.336 0.0248 2.25 3.3257 0.9991 2077990 Maybridge3_005166 CCSc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K19 compound treatment 0.321 0.0144 1.16 0.331 0.0198 1.8 2.0938 0.9777 1095724 Maybridge3_005167 CSc1nc(O)cc(n1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K20 compound treatment 0.33 0.0234 1.89 0.329 0.0178 1.62 2.4778 0.997 1436142 Maybridge3_005168 O=C(Oc1ccc(CC#N)cc1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K21 compound treatment 0.325 0.0184 1.48 0.327 0.0158 1.44 2.0648 0.9999 2077991 Maybridge3_005169 CC(=O)Nc1c(Cl)cc(Cl)c2cccnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K22 compound treatment 0.334 0.0274 2.21 0.335 0.0238 2.16 3.0907 0.9999 2077992 Maybridge3_005170 FC(F)(F)COc1ncccc1C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K23 mock treatment 0.308 0.00144 0.12 0.311 -1.88E-4 -0.02 0.0698 0.5967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 K24 positive control 0.094 -0.213 -17.12 0.094 -0.217 -19.71 -26.0437 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L01 compound treatment 0.322 0.0154 1.24 0.329 0.0178 1.62 2.0223 0.9916 2077993 Maybridge3_005171 CCOC(=O)c1n[nH]cc1c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L02 compound treatment 0.32 0.0134 1.08 0.327 0.0158 1.44 1.7801 0.9903 1396790 Maybridge3_005172 COc1ccc(CNC(=O)CSc2nc3cccnc3s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L03 compound treatment 0.32 0.0134 1.08 0.326 0.0148 1.34 1.7159 0.9942 2077994 Maybridge3_005173 Cc1cccc(N/C(=N\O)/c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L04 compound treatment 0.327 0.0204 1.65 0.334 0.0228 2.07 2.628 0.9935 2077995 Maybridge3_005174 Clc1ccc2c(Sc3nnc(NC(=O)c4cccs4)s3)ccnc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L05 compound treatment 0.328 0.0214 1.73 0.329 0.0178 1.62 2.364 0.9995 2077996 Maybridge3_005175 O/N=C(\Nc1ccccc1C(F)(F)F)/c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L06 compound treatment 0.318 0.0114 0.92 0.336 0.0248 2.25 2.2439 0.9221 2077997 Maybridge3_005176 CSc1c(C#N)c(N)nc(SCc2ccc(F)c(F)c2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L07 compound treatment 0.324 0.0174 1.4 0.334 0.0228 2.07 2.4571 0.9821 2077998 Maybridge3_005177 Cc1ccc(N/C(=N/O)/c2cnccc2C(F)(F)F)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L08 compound treatment 0.332 0.0254 2.05 0.336 0.0248 2.25 3.041 0.9989 1083641 Maybridge3_005178 CCOc1nc(N)c(C#N)c(c1C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L09 compound treatment 0.325 0.0184 1.48 0.334 0.0228 2.07 2.5141 0.9867 2077999 Maybridge3_005179 Clc1cccc(c1)c2nnc(o2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L10 compound treatment 0.319 0.0124 1.0 0.325 0.0138 1.25 1.5948 0.9938 1066693 Maybridge3_005180 OC(=O)Cc1ccc(OCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L11 compound treatment 0.321 0.0144 1.16 0.331 0.0198 1.8 2.0938 0.9777 2078000 Maybridge3_005181 Clc1ccccc1CN2C(=C)COC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L12 compound treatment 0.325 0.0184 1.48 0.332 0.0208 1.89 2.3857 0.9929 1345520 Maybridge3_005182 COC(=O)C1=C(C)NC(=O)CC1c2ccc(cc2)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L13 compound treatment 0.329 0.0224 1.81 0.327 0.0158 1.44 2.2925 0.9935 2078001 Maybridge3_005183 COc1ccncc1C(=O)Nc2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L14 compound treatment 0.325 0.0184 1.48 0.328 0.0168 1.53 2.129 0.9999 2078002 Maybridge3_005184 OC(=O)CC1=Nn2c(nnc2SC1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L15 compound treatment 0.351 0.0444 3.58 0.364 0.0528 4.79 5.9201 0.9896 2078003 Maybridge3_005185 Clc1ccc(cc1)C(=O)CC(C(=O)c2cccnc2)c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L16 compound treatment 0.329 0.0224 1.81 0.33 0.0188 1.71 2.4851 0.9996 1718647 Maybridge3_005186 COC(=O)C1=C(C)Nc2[nH]ncc2C1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L17 compound treatment 0.392 0.0854 6.88 0.405 0.0938 8.52 10.8862 0.9944 2078004 Maybridge3_005187 CCOC(=O)c1ccc2nc(N/C=N/O)sc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L18 compound treatment 0.318 0.0114 0.92 0.335 0.0238 2.16 2.1797 0.9277 2078005 Maybridge3_005188 CCC/1(CCCC\C1=N/O)c2cccc(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L19 compound treatment 0.365 0.0584 4.71 0.369 0.0578 5.25 7.0382 0.9985 2078006 Maybridge3_005189 Fc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L20 compound treatment 0.322 0.0154 1.24 0.324 0.0128 1.16 1.7014 0.9994 1680891 Maybridge3_005190 OC1N=C(c2cccc(O)c2)c3cc(Cl)ccc3NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L21 compound treatment 0.334 0.0274 2.21 0.338 0.0268 2.43 3.2833 0.9988 2078007 Maybridge3_005191 Cc1ccccc1COc2ncnc3cc(Cl)ccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L22 compound treatment 0.326 0.0194 1.57 0.326 0.0148 1.34 2.0575 0.9971 1317921 Maybridge3_005192 CC(C)N(CCO)S(=O)(=O)c1ccc(N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L23 mock treatment 0.312 0.00544 0.44 0.316 0.00481 0.44 0.6185 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 L24 positive control 0.095 -0.212 -17.04 0.093 -0.218 -19.81 -26.0509 -0.9972 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M01 compound treatment 0.311 0.00444 0.36 0.317 0.00581 0.53 0.6258 0.982 1432157 Maybridge3_005193 CC(C)NC(=O)Oc1noc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M02 compound treatment 0.318 0.0114 0.92 0.331 0.0198 1.8 1.9229 0.9517 2078008 Maybridge3_005194 CCN(C(=O)c1cnccc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M03 compound treatment 0.313 0.00644 0.52 0.324 0.0128 1.16 1.1889 0.9337 2078009 Maybridge3_005195 CC(=O)Nc1cccc(c1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M04 compound treatment 0.326 0.0194 1.57 0.332 0.0208 1.89 2.4426 0.9956 2078010 Maybridge3_005196 FC(F)(F)c1ccncc1c2nnc(o2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M05 compound treatment 0.316 0.00944 0.76 0.326 0.0148 1.34 1.4881 0.9635 2078011 Maybridge3_005197 Oc1cc(nc(n1)c2cccs2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M06 compound treatment 0.327 0.0204 1.65 0.332 0.0208 1.89 2.4996 0.9976 2078012 Maybridge3_005198 Cn1cc(Cl)c(n1)c2noc(n2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M07 compound treatment 0.329 0.0224 1.81 0.332 0.0208 1.89 2.6135 0.9998 2078013 Maybridge3_005199 Fc1cccc(F)c1C(=O)CSC(=S)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M08 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 2078014 Maybridge3_005200 Cc1nc(C(=O)NCC(=O)c2cccc(Cl)c2)c(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M09 compound treatment 0.354 0.0474 3.82 0.346 0.0348 3.16 4.9356 0.9956 1097098 Maybridge3_005201 O=c1oc(ns1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M10 compound treatment 0.329 0.0224 1.81 0.349 0.0378 3.43 3.7046 0.9551 2078015 Maybridge3_005202 CCOc1cc(c(cn1)C(=O)N(CC)Cc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M11 compound treatment 0.318 0.0114 0.92 0.317 0.00581 0.53 1.0243 0.965 1461277 Maybridge3_005203 CC(C)Nc1nc(cs1)c2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M12 compound treatment 0.329 0.0224 1.81 0.338 0.0268 2.43 2.9986 0.9892 2078016 Maybridge3_005204 CCc1cccc(CC)c1N(C)C(=O)c2cnccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M13 compound treatment 0.319 0.0124 1.0 0.32 0.00881 0.8 1.2738 0.9938 1633709 Maybridge3_005205 CSc1nc(N)nc(n1)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M14 compound treatment 0.335 0.0284 2.29 0.336 0.0248 2.25 3.2118 1.0 2078017 Maybridge3_005206 COC(=O)CSc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M15 compound treatment 0.311 0.00444 0.36 0.317 0.00581 0.53 0.6258 0.982 2078018 Maybridge3_005207 OCc1nc(cs1)c2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M16 compound treatment 0.317 0.0104 0.84 0.319 0.00781 0.71 1.0958 0.9964 2078019 Maybridge3_005208 NC(=O)c1cnc(cc1C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M17 compound treatment 0.322 0.0154 1.24 0.321 0.00981 0.89 1.5088 0.9866 2078020 Maybridge3_005209 CC(=O)OCC(=O)c1ccc(cc1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M18 compound treatment 0.326 0.0194 1.57 0.336 0.0248 2.25 2.6994 0.9842 2078021 Maybridge3_005210 CNc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M19 compound treatment 0.339 0.0324 2.61 0.343 0.0318 2.89 3.8889 0.9987 1614933 Maybridge3_005211 OC(=O)c1ccccc1C(=O)N(Cc2cccnc2)Cc3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M20 compound treatment 0.322 0.0154 1.24 0.332 0.0208 1.89 2.2149 0.9794 2078022 Maybridge3_005212 COC(=O)c1cnc(Oc2ccc(N)cc2)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M21 compound treatment 0.331 0.0244 1.97 0.332 0.0208 1.89 2.7273 0.9998 2078023 Maybridge3_005213 Oc1c2CSCCc2nn1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M22 compound treatment 0.339 0.0324 2.61 0.338 0.0268 2.43 3.568 0.9994 2078024 Maybridge3_005214 CCN(C(=O)c1cccnc1OCC(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M23 mock treatment 0.305 -0.00156 -0.13 0.306 -0.00519 -0.47 -0.4219 -0.8657 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 M24 positive control 0.096 -0.211 -16.96 0.098 -0.213 -19.35 -25.6731 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N01 compound treatment 0.333 0.0264 2.13 0.339 0.0278 2.52 3.2905 0.9964 1463277 Maybridge3_005215 CSc1[nH]nc(c1SC(=O)N(C)C)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N02 compound treatment 0.317 0.0104 0.84 0.325 0.0138 1.25 1.4809 0.9811 1460875 Maybridge3_005216 COc1cccc(CNC(=O)CSc2nc3cccnc3s2)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N03 compound treatment 0.312 0.00544 0.44 0.317 0.00581 0.53 0.6827 0.9957 2078025 Maybridge3_005217 O/N=C(\Nc1cccc(c1)C(F)(F)F)/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N04 compound treatment 0.319 0.0124 1.0 0.331 0.0198 1.8 1.9799 0.9618 1529579 Maybridge3_005218 CC(=O)N1CCc2cccc(N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N05 compound treatment 0.317 0.0104 0.84 0.327 0.0158 1.44 1.6092 0.9675 1247459 Maybridge3_005219 Cc1ccccc1n2c(noc2=O)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N06 compound treatment 0.362 0.0554 4.46 0.371 0.0598 5.43 6.9957 0.9953 2078026 Maybridge3_005220 CSc1c(C#N)c(N)nc(SCC(=O)c2ccccc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N07 compound treatment 0.32 0.0134 1.08 0.335 0.0238 2.16 2.2935 0.9488 2078027 Maybridge3_005221 O/N=C(\Nc1ccc(Cl)cc1Cl)/c2cnccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N08 compound treatment 0.333 0.0264 2.13 0.339 0.0278 2.52 3.2905 0.9964 2078028 Maybridge3_005222 CC(C)(C)C1NC(CS1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N09 compound treatment 0.327 0.0204 1.65 0.335 0.0238 2.16 2.6921 0.9909 2078029 Maybridge3_005223 Clc1cccc(Cl)c1c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N10 compound treatment 0.324 0.0174 1.4 0.341 0.0298 2.71 2.9064 0.9533 1681856 Maybridge3_005224 Cc1nn(c2ccccc2)c3[nH]c4ccccc4c(=O)c13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N11 compound treatment 0.321 0.0144 1.16 0.336 0.0248 2.25 2.4147 0.9527 2078030 Maybridge3_005225 COc1cccc(OC)c1CNC(=O)c2cnccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N12 compound treatment 0.322 0.0154 1.24 0.33 0.0188 1.71 2.0865 0.9878 2078031 Maybridge3_005226 CCC(=O)Nc1ccc(cc1C)c2nnc(o2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N13 compound treatment 0.323 0.0164 1.32 0.33 0.0188 1.71 2.1434 0.9921 1032913 Maybridge3_005227 Clc1ccccc1C2CC(=O)c3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N14 compound treatment 0.344 0.0374 3.01 0.358 0.0468 4.25 5.1364 0.9859 1479452 Maybridge3_005228 CCOC(=O)c1c(C)n(C2CC2)c3ccc(OC)cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N15 compound treatment 0.396 0.0894 7.2 0.405 0.0938 8.52 11.114 0.9965 2078032 Maybridge3_005229 O=C/1NC(=N\C1=C\c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N16 compound treatment 0.322 0.0154 1.24 0.323 0.0118 1.07 1.6372 0.9973 2078033 Maybridge3_005230 CO/C=N/c1nc-2c(CCc3ccccc23)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N17 compound treatment 0.317 0.0104 0.84 0.322 0.0108 0.98 1.2883 0.997 2078034 Maybridge3_005231 CCOC(=O)CSc1nc2c(C)ccc(F)c2cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N18 compound treatment 0.323 0.0164 1.32 0.329 0.0178 1.62 2.0793 0.9951 1491062 Maybridge3_005232 NC(=O)c1ccccc1OCC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N19 compound treatment 0.321 0.0144 1.16 0.323 0.0118 1.07 1.5803 0.9992 1535120 Maybridge3_005233 Oc1c(C2CCCCC2)c(=O)n3CCCc4cccc1c43 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N20 compound treatment 0.318 0.0114 0.92 0.331 0.0198 1.8 1.9229 0.9517 1174232 Maybridge3_005234 CC1(C)C2CCC1(C)C(C2)N3CCNCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N21 compound treatment 0.329 0.0224 1.81 0.334 0.0228 2.07 2.7418 0.9977 1352902 Maybridge3_005235 Cc1ccc2ncnc(Oc3ncccc3N)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N22 compound treatment 0.327 0.0204 1.65 0.333 0.0218 1.98 2.5638 0.9958 2078035 Maybridge3_005236 CN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N23 mock treatment 0.312 0.00544 0.44 0.317 0.00581 0.53 0.6827 0.9957 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 N24 positive control 0.097 -0.21 -16.88 0.093 -0.218 -19.81 -25.937 -0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O01 compound treatment 0.332 0.0254 2.05 0.337 0.0258 2.34 3.1052 0.9978 2078036 Maybridge3_005237 Cc1cc(C)c2c(=O)c(coc2c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O02 compound treatment 0.326 0.0194 1.57 0.33 0.0188 1.71 2.3143 0.9991 2078037 Maybridge3_005238 CCOc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O03 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 2078038 Maybridge3_005239 CC(CC#N)C(=O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O04 compound treatment 0.325 0.0184 1.48 0.33 0.0188 1.71 2.2573 0.9976 2078039 Maybridge3_005240 CC(C)(C)c1nnc(o1)c2cnccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O05 compound treatment 0.319 0.0124 1.0 0.329 0.0178 1.62 1.8515 0.9735 2078040 Maybridge3_005241 OCc1cc(no1)c2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O06 compound treatment 0.323 0.0164 1.32 0.334 0.0228 2.07 2.4002 0.9766 2078041 Maybridge3_005242 CCOC(=O)c1cc(n[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O07 compound treatment 0.325 0.0184 1.48 0.334 0.0228 2.07 2.5141 0.9867 1238161 Maybridge3_005243 Clc1ccc(cc1)C(=O)CSC(=S)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O08 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 1575872 Maybridge3_005244 CC(C)(OC(=O)Nc1ccc(Cl)cc1)C#Cc2cncnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O09 compound treatment 0.341 0.0344 2.77 0.355 0.0438 3.98 4.773 0.9845 2078042 Maybridge3_005245 O=c1oc(ns1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O10 compound treatment 0.34 0.0334 2.69 0.375 0.0638 5.79 5.9998 0.9393 2078043 Maybridge3_005246 COc1cc(c(cn1)C(=O)N(C)Cc2cc(Cl)cc(Cl)c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O11 compound treatment 0.323 0.0164 1.32 0.331 0.0198 1.8 2.2076 0.9886 2078044 Maybridge3_005247 Clc1ccc(cc1)C(=O)NCC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O12 compound treatment 0.339 0.0324 2.61 0.343 0.0318 2.89 3.8889 0.9987 2078045 Maybridge3_005248 CN(C(=O)c1cnccc1C(F)(F)F)c2cccc(C)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O13 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 1663601 Maybridge3_005249 CC(C)c1nc(N)nc(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O14 compound treatment 0.349 0.0424 3.42 0.36 0.0488 4.43 5.5495 0.9918 2078046 Maybridge3_005250 CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O15 compound treatment 0.326 0.0194 1.57 0.327 0.0158 1.44 2.1217 0.9991 2078047 Maybridge3_005251 Cc1cc(/N=C/c2cccnc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O16 compound treatment 0.317 0.0104 0.84 0.323 0.0118 1.07 1.3525 0.9927 2078048 Maybridge3_005252 FC(F)(F)c1ccccc1n2nnnc2c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O17 compound treatment 0.328 0.0214 1.73 0.336 0.0248 2.25 2.8133 0.9914 2078049 Maybridge3_005253 CC(C)(C)C(=O)OCC(=O)c1ccc(cc1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O18 compound treatment 0.319 0.0124 1.0 0.338 0.0268 2.43 2.4292 0.923 2078050 Maybridge3_005254 CN(C)CCSc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O19 compound treatment 0.343 0.0364 2.93 0.352 0.0408 3.7 4.6943 0.9933 1255779 Maybridge3_005255 CC1=CCC(C(C1)C(=O)O)C(=O)N(Cc2cccnc2)Cc3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O20 compound treatment 0.327 0.0204 1.65 0.333 0.0218 1.98 2.5638 0.9958 2078051 Maybridge3_005256 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(cn2)C(F)(F)F)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O21 compound treatment 0.328 0.0214 1.73 0.33 0.0188 1.71 2.4282 1.0 1361645 Maybridge3_005257 Oc1nc(nc2CCSCc12)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O22 compound treatment 0.329 0.0224 1.81 0.331 0.0198 1.8 2.5493 1.0 2078052 Maybridge3_005258 CC1OC(=O)N(C1=O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O23 mock treatment 0.314 0.00744 0.6 0.318 0.00681 0.62 0.8608 0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 O24 positive control 0.096 -0.211 -16.96 0.092 -0.219 -19.9 -26.0582 -0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P01 compound treatment 0.396 0.0894 7.2 0.409 0.0978 8.88 11.3707 0.9946 2078053 Maybridge3_005259 CNC(=O)Sc1c(SC)n(nc1c2ccc(Cl)cc2)C(=O)NC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P02 compound treatment 0.322 0.0154 1.24 0.328 0.0168 1.53 1.9581 0.9948 1629161 Maybridge3_005260 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P03 compound treatment 0.328 0.0214 1.73 0.331 0.0198 1.8 2.4923 0.9998 2078054 Maybridge3_005261 O/N=C(\Nc1ccc(cc1)C(F)(F)F)/c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P04 compound treatment 0.327 0.0204 1.65 0.331 0.0198 1.8 2.4354 0.999 1350307 Maybridge3_005262 COC(=O)C1(C)Oc2cc(Cl)ccc2NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P05 compound treatment 0.326 0.0194 1.57 0.324 0.0128 1.16 1.9292 0.9893 2078055 Maybridge3_005263 FC(F)(F)c1ccccc1n2c(noc2=O)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P06 compound treatment 0.322 0.0154 1.24 0.335 0.0238 2.16 2.4074 0.9655 1605723 Maybridge3_005264 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccc(F)c(F)c3)c(N)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P07 compound treatment 0.325 0.0184 1.48 0.334 0.0228 2.07 2.5141 0.9867 2078056 Maybridge3_005265 FC(F)(F)c1ccncc1c2noc(=O)n2c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P08 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 2078057 Maybridge3_005266 Cc1ccc(cc1)c2nn[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P09 compound treatment 0.363 0.0564 4.54 0.369 0.0578 5.25 6.9243 0.9974 2078058 Maybridge3_005267 FC(F)(F)c1ccc(cc1)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P10 compound treatment 0.325 0.0184 1.48 0.347 0.0358 3.25 3.3485 0.937 1465285 Maybridge3_005268 COc1ccc(cc1)n2nc(C)cc2Nc3ccccc3C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P11 compound treatment 0.326 0.0194 1.57 0.33 0.0188 1.71 2.3143 0.9991 2078059 Maybridge3_005269 Clc1ccc(Cn2ncc(Br)c2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P12 compound treatment 0.316 0.00944 0.76 0.318 0.00681 0.62 0.9746 0.9948 1728956 Maybridge3_005270 C(N1CCCCC1)c2csc(Nc3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P13 compound treatment 0.334 0.0274 2.21 0.338 0.0268 2.43 3.2833 0.9988 2078060 Maybridge3_005271 Oc1ccccc1c2cc(n[nH]2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P14 compound treatment 0.324 0.0174 1.4 0.327 0.0158 1.44 2.0078 0.9999 2078061 Maybridge3_005272 CN(C(=O)C)c1cccnc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P15 compound treatment 0.325 0.0184 1.48 0.329 0.0178 1.62 2.1931 0.9991 1575180 Maybridge3_005273 CC(C)(Oc1ccc(C#N)cc1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P16 compound treatment 0.327 0.0204 1.65 0.332 0.0208 1.89 2.4996 0.9976 1266077 Maybridge3_005274 CC(=O)Nc1nc-2c(Cc3ccccc23)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P17 compound treatment 0.323 0.0164 1.32 0.326 0.0148 1.34 1.8867 1.0 2078062 Maybridge3_005275 Clc1ccc(Sc2ccc3nnc(c4ccccc4)n3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P18 compound treatment 0.33 0.0234 1.89 0.342 0.0308 2.8 3.3123 0.9817 1141653 Maybridge3_005276 Cc1c(OCC(=O)NCC=C)ccc2C(=O)CC(C)(C)Oc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P19 compound treatment 0.36 0.0534 4.3 0.365 0.0538 4.88 6.4967 0.998 2078063 Maybridge3_005277 Cc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P20 compound treatment 0.324 0.0174 1.4 0.329 0.0178 1.62 2.1362 0.9975 2078064 Maybridge3_005278 COc1cccc(c1)C/2CCCC\C2=N\O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P21 compound treatment 0.329 0.0224 1.81 0.332 0.0208 1.89 2.6135 0.9998 1642742 Maybridge3_005279 CC(=O)Nc1ccc(F)c(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P22 compound treatment 0.325 0.0184 1.48 0.327 0.0158 1.44 2.0648 0.9999 1258357 Maybridge3_005280 Cc1ccc(OCC(=O)O)c2CCCc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P23 mock treatment 0.313 0.00644 0.52 0.315 0.00381 0.35 0.6113 0.9807 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1445 P24 positive control 0.097 -0.21 -16.88 0.093 -0.218 -19.81 -25.937 -0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A01 compound treatment 0.306 0.00175 0.14 0.306 0.00369 0.33 0.3363 0.9261 1262176 Maybridge3_005281 CN1C=NC(O)(c2ccccc2)c3cc(Cl)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A02 compound treatment 0.304 -2.5E-4 -0.02 0.314 0.0117 1.06 0.7359 0.6936 2078065 Maybridge3_005282 CCC/C(=N\O)/c1ccccn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A03 compound treatment 0.299 -0.00525 -0.42 0.304 0.00169 0.15 -0.1906 -0.4239 1178270 Maybridge3_005283 CCc1ccc(cc1)C(=O)Nc2cccnc2Oc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A04 compound treatment 0.303 -0.00125 -0.1 0.304 0.00169 0.15 0.0371 0.2026 2078066 Maybridge3_005284 COc1ccc(cc1)c2ccc(OC)cc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A05 compound treatment 0.301 -0.00325 -0.26 0.303 6.88E-4 0.06 -0.1409 -0.5238 1673293 Maybridge3_005285 COc1ccc(COc2cccnc2N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A06 compound treatment 0.297 -0.00725 -0.58 0.303 6.88E-4 0.06 -0.3687 -0.6279 1016235 Maybridge3_005286 O=c1cc(oc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A07 compound treatment 0.302 -0.00225 -0.18 0.316 0.0137 1.24 0.7504 0.5977 1303077 Maybridge3_005287 Cc1ccc(Sc2ncccc2NC(=O)C(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A08 compound treatment 0.299 -0.00525 -0.42 0.309 0.00669 0.61 0.1303 0.1761 1618605 Maybridge3_005288 COc1ccc(CC2(O)CCC3(CC2)OCCO3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A09 compound treatment 0.282 -0.0222 -1.79 0.286 -0.0163 -1.48 -2.314 -0.9955 1474271 Maybridge3_005289 COc1ccc2nc(cc(NCCN(C)C)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A10 compound treatment 0.292 -0.0123 -0.99 0.297 -0.00531 -0.48 -1.0385 -0.9458 1914510 Maybridge3_005290 CN(S(=O)(=O)c1ccc(F)cc1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A11 compound treatment 0.312 0.00775 0.62 0.319 0.0167 1.51 1.5124 0.9232 2078067 Maybridge3_005291 CCOC(=O)COc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A12 compound treatment 0.302 -0.00225 -0.18 0.311 0.00869 0.79 0.4295 0.5308 2078068 Maybridge3_005292 CC1CN=C(Nc2ccc(F)cc2F)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A13 compound treatment 0.307 0.00275 0.22 0.307 0.00469 0.43 0.4575 0.9537 2078069 Maybridge3_005293 COc1nc(C)cc(c1C#N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A14 compound treatment 0.31 0.00575 0.46 0.31 0.00769 0.7 0.8208 0.9802 2078070 Maybridge3_005294 CC1(C)NCSC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A15 compound treatment 0.316 0.0118 0.95 0.306 0.00369 0.33 0.9057 0.9024 2078071 Maybridge3_005295 CCOC(=O)c1csc(n1)n2cccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A16 compound treatment 0.306 0.00175 0.14 0.307 0.00469 0.43 0.4005 0.8936 1377776 Maybridge3_005296 COc1ccc(cc1)C(=O)NCC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A17 compound treatment 0.305 7.5E-4 0.06 0.307 0.00469 0.43 0.3436 0.7995 1368851 Maybridge3_005297 CC1(C)CC(=O)c2ccc(OCC#N)cc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A18 compound treatment 0.308 0.00375 0.3 0.309 0.00669 0.61 0.6428 0.948 1919002 Maybridge3_005298 Fc1c(F)c(F)c(NS(=O)(=O)C2CCS(=O)(=O)C2)c(F)c1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A19 compound treatment 0.31 0.00575 0.46 0.305 0.00269 0.24 0.4999 0.9552 2078072 Maybridge3_005299 CSc1cc(=O)c2ccccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A20 compound treatment 0.309 0.00475 0.38 0.311 0.00869 0.79 0.8281 0.9448 1698058 Maybridge3_005300 COC1OC(OC)C2C1C3CCC2C(O)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A21 compound treatment 0.299 -0.00525 -0.42 0.295 -0.00731 -0.66 -0.7683 -0.9763 1385755 Maybridge3_005301 NCC(c1ccccc1)c2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A22 compound treatment 0.293 -0.0113 -0.91 0.294 -0.00831 -0.75 -1.1741 -0.9959 2078073 Maybridge3_005302 Clc1ccc(OCCCN2CCN(CC2)c3cccc4[nH]ccc34)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A23 mock treatment 0.294 -0.0103 -0.83 0.295 -0.00731 -0.66 -1.053 -0.9942 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 A24 positive control 0.085 -0.219 -17.66 0.086 -0.216 -19.63 -26.3683 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B01 compound treatment 0.342 0.0377 3.04 0.334 0.0317 2.88 4.1834 0.9996 1576065 Maybridge3_005303 O=C(C1CCCCC1)N2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B02 compound treatment 0.341 0.0367 2.96 0.327 0.0247 2.24 3.6771 0.9906 2078074 Maybridge3_005304 Oc1cc(nc(SCC(=O)c2ccc(Cl)cc2)n1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B03 compound treatment 0.327 0.0227 1.83 0.322 0.0197 1.79 2.559 0.9999 1029362 Maybridge3_005305 COC(=O)C(Cc1ccccc1)NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B04 compound treatment 0.353 0.0488 3.93 0.341 0.0387 3.51 5.259 0.9985 2078075 Maybridge3_005306 CC[n+]1c(C)csc1Nc2ccc(cc2)N3CC(C)OC(C)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B05 compound treatment 0.341 0.0367 2.96 0.349 0.0467 4.24 5.0892 0.9846 1662988 Maybridge3_005307 Oc1nc(sc(=O)c1Cc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B06 compound treatment 0.321 0.0168 1.35 0.321 0.0187 1.7 2.1532 0.9936 2078076 Maybridge3_005308 CCSc1nc(O)cc(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B07 compound treatment 0.323 0.0187 1.51 0.318 0.0157 1.42 2.0745 0.9996 1683883 Maybridge3_005309 Oc1c(c2ccccc2)c(=O)[nH]c3cc(Cl)c(Cl)cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B08 compound treatment 0.322 0.0177 1.43 0.322 0.0197 1.79 2.2743 0.9939 1380299 Maybridge3_005310 Cc1cccc(Nc2ncnc(N)n2)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B09 compound treatment 0.311 0.00675 0.54 0.307 0.00469 0.43 0.6852 0.9927 1691877 Maybridge3_005311 CN(C)CCNc1cc(nc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B10 compound treatment 0.337 0.0328 2.64 0.335 0.0327 2.97 3.9629 0.9983 2078077 Maybridge3_005312 FC(F)(F)c1cccc(Nc2ncnc(n2)n3cccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B11 compound treatment 0.324 0.0198 1.59 0.321 0.0187 1.7 2.324 0.9995 1405740 Maybridge3_005313 CC(Cc1ccccc1)(Nc2ccc(Cl)cc2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B12 compound treatment 0.325 0.0208 1.67 0.32 0.0177 1.61 2.3168 0.9998 2078078 Maybridge3_005314 Nc1nc(N)nc(n1)c2ccccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B13 compound treatment 0.322 0.0177 1.43 0.317 0.0147 1.33 1.9534 0.9994 1151988 Maybridge3_005315 CCCC1C(NC(CC1=O)c2ccco2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B14 compound treatment 0.342 0.0377 3.04 0.343 0.0407 3.69 4.761 0.9953 1733095 Maybridge3_005316 COCc1cc(=O)oc2cc(NS(=O)(=O)C)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B15 compound treatment 0.315 0.0107 0.87 0.316 0.0137 1.24 1.4906 0.9844 2078079 Maybridge3_005317 CCc1nc2cccc3cccc([nH]1)c32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B16 compound treatment 0.323 0.0187 1.51 0.318 0.0157 1.42 2.0745 0.9996 2078080 Maybridge3_005318 COc1cc(/C=N/c2ccc(Cl)cc2)ccc1OC(=O)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B17 compound treatment 0.319 0.0147 1.19 0.319 0.0167 1.51 1.911 0.9928 2078081 Maybridge3_005319 NC(=O)c1ccccc1OCCCN2CCN(CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B18 compound treatment 0.334 0.0297 2.4 0.321 0.0187 1.7 2.8934 0.9857 1520180 Maybridge3_005320 Cc1cc(O)nc(NC(=O)C(C)(C)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B19 compound treatment 0.324 0.0198 1.59 0.322 0.0197 1.79 2.3882 0.9983 2078082 Maybridge3_005321 Nc1nnc(o1)c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B20 compound treatment 0.329 0.0248 1.99 0.321 0.0187 1.7 2.6087 0.9968 2078083 Maybridge3_005322 CCCc1nc(SC)nc(O)c1CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B21 compound treatment 0.339 0.0348 2.8 0.335 0.0327 2.97 4.0767 0.9996 1160001 Maybridge3_005323 O=C(Oc1cc(=O)n2CCCc3cccc1c32)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B22 compound treatment 0.319 0.0147 1.19 0.316 0.0137 1.24 1.7184 0.9997 2078084 Maybridge3_005324 FC(F)(F)c1cccc(c1)N(C(=O)c2ccco2)C3=NCCCC(=O)S3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B23 mock treatment 0.308 0.00375 0.3 0.307 0.00469 0.43 0.5144 0.9859 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 B24 positive control 0.083 -0.221 -17.82 0.087 -0.215 -19.54 -26.418 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C01 compound treatment 0.325 0.0208 1.67 0.316 0.0137 1.24 2.0601 0.9894 1006770 Maybridge3_005325 CCOC(=O)c1cc2ccccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C02 compound treatment 0.413 0.109 8.76 0.404 0.102 9.23 12.7191 0.9997 2078085 Maybridge3_005326 CC(C)(C)C(=O)/C=C\1/Nc2ccccc2NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C03 compound treatment 0.309 0.00475 0.38 0.303 6.88E-4 0.06 0.3146 0.8117 2078086 Maybridge3_005327 CCOC(=O)Cn1c2ccccc2c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C04 compound treatment 0.315 0.0107 0.87 0.325 0.0227 2.06 2.0683 0.9259 1118001 Maybridge3_005328 CN1C(CC(=O)C2(O)CCCCC12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C05 compound treatment 0.314 0.00975 0.79 0.312 0.00969 0.88 1.177 0.9984 1590446 Maybridge3_005329 Clc1ccc(Oc2ncccc2NS(=O)(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C06 compound treatment 0.318 0.0138 1.11 0.32 0.0177 1.61 1.9182 0.9835 2078087 Maybridge3_005330 CC(=O)OC1C(Oc2ccccc2C1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C07 compound treatment 0.344 0.0398 3.2 0.336 0.0337 3.06 4.4256 0.9997 1640580 Maybridge3_005331 Cc1ccc(cc1)S(=O)(=O)Nc2ncccc2OCc3cc(F)cc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C08 compound treatment 0.312 0.00775 0.62 0.317 0.0147 1.33 1.384 0.9402 1606796 Maybridge3_005332 COc1ccccc1C2(O)CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C09 compound treatment 0.328 0.0238 1.91 0.319 0.0167 1.51 2.4234 0.9933 1547687 Maybridge3_005333 CN1CCN(CC1)C(=O)COc2cc(nc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C10 compound treatment 0.355 0.0508 4.09 0.349 0.0467 4.24 5.8864 0.9998 1347240 Maybridge3_005334 OC1CCN(CC1)C(=O)Oc2ccc(Oc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C11 compound treatment 0.314 0.00975 0.79 0.309 0.00669 0.61 0.9844 0.9919 2078088 Maybridge3_005335 CC(=O)n1c(=O)oc2ccc(C)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C12 compound treatment 0.326 0.0217 1.75 0.319 0.0167 1.51 2.3096 0.9974 1302672 Maybridge3_005336 Cc1n[nH]c(N)c1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C13 compound treatment 0.319 0.0147 1.19 0.308 0.00569 0.52 1.2049 0.9304 1480604 Maybridge3_005337 CCOC(=O)c1cc2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C14 compound treatment 0.374 0.0698 5.62 0.368 0.0657 5.96 8.1878 0.9996 1057854 Maybridge3_005338 CCC1NC(CS1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C15 compound treatment 0.326 0.0217 1.75 0.309 0.00669 0.61 1.6677 0.8997 2078089 Maybridge3_005339 COC(=O)c1sc2cc(Cl)ccc2c1OC(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C16 compound treatment 0.329 0.0248 1.99 0.329 0.0267 2.42 3.1222 0.9953 1722093 Maybridge3_005340 CCCSc1ccc2[nH]c(NC(=O)C)nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C17 compound treatment 0.322 0.0177 1.43 0.321 0.0187 1.7 2.2102 0.9964 1383819 Maybridge3_005341 CC1(C)CC(=O)c2ccc(OCc3ccc(F)cc3)cc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C18 compound treatment 0.329 0.0248 1.99 0.323 0.0207 1.88 2.7371 0.9996 2078090 Maybridge3_005342 COC(=O)N1C2CC(C=C2)C1(C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C19 compound treatment 0.349 0.0447 3.6 0.345 0.0427 3.87 5.288 0.9993 2078091 Maybridge3_005343 CCOC(=O)C1=C(SC)/C(=N\O)/NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C20 compound treatment 0.319 0.0147 1.19 0.318 0.0157 1.42 1.8468 0.9959 1155369 Maybridge3_005344 Cc1ccc(CN2CCC(CC2)NC(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C21 compound treatment 0.315 0.0107 0.87 0.31 0.00769 0.7 1.1055 0.9943 2078092 Maybridge3_005345 O=C/1ON(C(=O)\C1=C\c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C22 compound treatment 0.312 0.00775 0.62 0.31 0.00769 0.7 0.9347 0.9984 1586669 Maybridge3_005346 Cc1ccc(CN2CCN(CC2)c3cccc4[nH]ccc34)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C23 mock treatment 0.298 -0.00625 -0.5 0.295 -0.00731 -0.66 -0.8252 -0.9907 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 C24 positive control 0.083 -0.221 -17.82 0.09 -0.212 -19.27 -26.2255 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D01 compound treatment 0.351 0.0468 3.76 0.35 0.0477 4.33 5.7228 0.9976 1138004 Maybridge3_005347 Clc1ccc(c(Cl)c1)S(=O)(=O)N2CCN(CC2)C(=O)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D02 compound treatment 0.355 0.0508 4.09 0.349 0.0467 4.24 5.8864 0.9998 2078093 Maybridge3_005348 CN(C)C(=O)Oc1nc(SCc2c(F)cccc2Cl)nc(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D03 compound treatment 0.318 0.0138 1.11 0.312 0.00969 0.88 1.4047 0.9935 1031352 Maybridge3_005349 O=C(CCCC(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D04 compound treatment 0.326 0.0217 1.75 0.315 0.0127 1.15 2.0528 0.9793 2078094 Maybridge3_005350 Clc1cc(Cl)cc(NC(=O)C2CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D05 compound treatment 0.321 0.0168 1.35 0.304 0.00169 0.15 1.0621 0.7824 1144979 Maybridge3_005351 CC1(C)c2ccccc2-n3c1cc(O)c(Cc4ccccc4)c3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D06 compound treatment 0.33 0.0257 2.07 0.323 0.0207 1.88 2.7941 0.9988 1302814 Maybridge3_005352 COCc1cc(=O)oc2cc(OC(=O)N(C)C)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D07 compound treatment 0.331 0.0267 2.15 0.33 0.0277 2.51 3.3003 0.9971 1426387 Maybridge3_005353 Oc1cc2nnnn2nc1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D08 compound treatment 0.326 0.0217 1.75 0.323 0.0207 1.88 2.5663 0.9994 2078095 Maybridge3_005354 Nc1ncnc(Nc2ccc(F)cc2Br)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D09 compound treatment 0.311 0.00675 0.54 0.305 0.00269 0.24 0.5568 0.9346 1137849 Maybridge3_005355 CCN(CC)CCNc1cc(nc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D10 compound treatment 0.336 0.0318 2.56 0.324 0.0217 1.97 3.1999 0.9917 1616809 Maybridge3_005356 COc1ccccc1Nc2ncnc(n2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D11 compound treatment 0.349 0.0447 3.6 0.347 0.0447 4.06 5.4164 0.9983 2078096 Maybridge3_005357 CC/1C(N(C)C(C\C1=N\O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D12 compound treatment 0.362 0.0578 4.65 0.365 0.0627 5.69 7.3119 0.995 2078097 Maybridge3_005358 COCc1cc(OC(=O)N(C)C)nc(n1)c2ccc(C)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D13 compound treatment 0.468 0.164 13.19 0.443 0.141 12.77 18.3541 0.9999 2078098 Maybridge3_005359 CN1C(=O)/C(=C\Nc2ccccc2)/C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D14 compound treatment 0.337 0.0328 2.64 0.322 0.0197 1.79 3.1285 0.982 1614259 Maybridge3_005360 COCc1cc(=O)oc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D15 compound treatment 0.31 0.00575 0.46 0.302 -3.12E-4 -0.03 0.3074 0.6625 1460864 Maybridge3_005361 Clc1c(Cc2ccccc2)c(=O)oc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D16 compound treatment 0.37 0.0658 5.29 0.359 0.0567 5.15 7.3824 0.9999 1250098 Maybridge3_005362 Cc1n[nH]c2oc(=O)c(Cc3c(F)cccc3Cl)c(C)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D17 compound treatment 0.333 0.0288 2.32 0.321 0.0187 1.7 2.8365 0.9883 2078099 Maybridge3_005363 CC(=O)NC(=O)c1ocnc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D18 compound treatment 0.366 0.0617 4.97 0.362 0.0597 5.42 7.3471 0.9991 1307545 Maybridge3_005364 Cc1cc(NCC2CC2)n3nc(Nc4cc(Cl)ccc4C)nc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D19 compound treatment 0.328 0.0238 1.91 0.326 0.0237 2.15 2.8727 0.9983 2078100 Maybridge3_005365 NC(=O)c1c(/N=C/c2cc(Br)ccc2O)sc3CCCCc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D20 compound treatment 0.326 0.0217 1.75 0.323 0.0207 1.88 2.5663 0.9994 2078101 Maybridge3_005366 CCc1cccc(C)c1NC2=NCCC(=O)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D21 compound treatment 0.343 0.0388 3.12 0.333 0.0307 2.79 4.1761 0.9984 2078102 Maybridge3_005367 CCOC(=O)c1c(C)n[nH]c1/N=C/c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D22 compound treatment 0.321 0.0168 1.35 0.322 0.0197 1.79 2.2174 0.9904 2078103 Maybridge3_005368 COCc1nc(SCC2CC2)nc(O)c1CC(=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D23 mock treatment 0.307 0.00275 0.22 0.3 -0.00231 -0.21 0.0082 0.0267 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 D24 positive control 0.084 -0.22 -17.74 0.091 -0.211 -19.18 -26.1043 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E01 compound treatment 0.337 0.0328 2.64 0.32 0.0177 1.61 3.0001 0.9717 1121092 Maybridge3_005369 COc1ccccc1N2CCN(CC(C)Nc3ccccn3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E02 compound treatment 0.332 0.0278 2.23 0.321 0.0187 1.7 2.7796 0.9908 2078104 Maybridge3_005370 O/N=C(\C1CCCCC1)/c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E03 compound treatment 0.321 0.0168 1.35 0.312 0.00969 0.88 1.5756 0.9785 1594825 Maybridge3_005371 Clc1ccc(Oc2ncccc2NC(=O)c3ccccc3Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E04 compound treatment 0.323 0.0187 1.51 0.318 0.0157 1.42 2.0745 0.9996 1285664 Maybridge3_005372 Cc1cccc2C(=O)C(C(=O)Nc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E05 compound treatment 0.303 -0.00125 -0.1 0.3 -0.00231 -0.21 -0.2196 -0.9433 2078105 Maybridge3_005373 CS(=O)(=O)NCCNc1cc(nc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E06 compound treatment 0.319 0.0147 1.19 0.32 0.0177 1.61 1.9752 0.989 873833 Maybridge3_005374 COC(=O)C(C)(N)Cc1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E07 compound treatment 0.332 0.0278 2.23 0.322 0.0197 1.79 2.8438 0.9939 1378223 Maybridge3_005375 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E08 compound treatment 0.325 0.0208 1.67 0.318 0.0157 1.42 2.1884 0.9968 1297666 Maybridge3_005376 COC(=O)C1CN(Cc2ccccc2)CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E09 compound treatment 0.331 0.0267 2.15 0.316 0.0137 1.24 2.4017 0.9658 1316338 Maybridge3_005377 Cc1ccc(Sc2ncccc2NS(=O)(=O)c3ccc(F)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E10 compound treatment 0.344 0.0398 3.2 0.337 0.0347 3.15 4.4898 1.0 1208025 Maybridge3_005378 CCC1(CCCCN(C)C1=O)c2cccc(OC)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E11 compound treatment 0.329 0.0248 1.99 0.319 0.0167 1.51 2.4804 0.9908 2078106 Maybridge3_005379 CSc1nccc(n1)c2sc(nc2C)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E12 compound treatment 0.322 0.0177 1.43 0.325 0.0227 2.06 2.4669 0.9841 1160883 Maybridge3_005380 O=S(=O)(C1CCS(=O)(=O)C1)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E13 compound treatment 0.321 0.0168 1.35 0.314 0.0117 1.06 1.7039 0.9929 1732082 Maybridge3_005381 Cc1ccc2cc(NC(=O)Cc3ccccc3)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E14 compound treatment 0.34 0.0357 2.88 0.332 0.0297 2.69 3.9411 0.9995 2078107 Maybridge3_005382 COC(=O)Cn1nnnc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E15 compound treatment 0.332 0.0278 2.23 0.327 0.0247 2.24 3.1647 1.0 1265272 Maybridge3_005383 CCOC(=O)COc1ccc(Cl)cc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E16 compound treatment 0.325 0.0208 1.67 0.316 0.0137 1.24 2.0601 0.9894 1035162 Maybridge3_005384 O=C(NCC#N)OCc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E17 compound treatment 0.313 0.00875 0.7 0.321 0.0187 1.7 1.6977 0.9243 1205724 Maybridge3_005385 CC1(C)CC(=O)c2ccc(OCC(=O)Nc3ccc(Br)cc3)cc2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E18 compound treatment 0.33 0.0257 2.07 0.322 0.0197 1.79 2.7299 0.9973 1369945 Maybridge3_005386 CC(C1CC1)N(C(=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E19 compound treatment 0.324 0.0198 1.59 0.309 0.00669 0.61 1.5538 0.9128 1716844 Maybridge3_005387 CC(=O)N1C(=O)CC(Sc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E20 compound treatment 0.322 0.0177 1.43 0.31 0.00769 0.7 1.5041 0.9456 1250634 Maybridge3_005388 Clc1ccccc1CN2CCC(CC2)NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E21 compound treatment 0.326 0.0217 1.75 0.318 0.0157 1.42 2.2454 0.9947 2078108 Maybridge3_005389 Cc1ccnc(/N=C\2/N(Cc3ccccc23)c4cc(C)ccn4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E22 compound treatment 0.318 0.0138 1.11 0.322 0.0197 1.79 2.0466 0.9735 2078109 Maybridge3_005390 Clc1ccc(OCCCN2CCN(Cc3ccccc3)CC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E23 mock treatment 0.298 -0.00625 -0.5 0.296 -0.00631 -0.57 -0.761 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 E24 positive control 0.087 -0.217 -17.49 0.093 -0.209 -19.0 -25.8051 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F01 compound treatment 0.328 0.0238 1.91 0.327 0.0247 2.24 2.9369 0.9969 1481367 Maybridge3_005391 COC(=O)c1c(O)c2ccccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F02 compound treatment 0.33 0.0257 2.07 0.319 0.0167 1.51 2.5373 0.9881 1668909 Maybridge3_005392 Clc1ccc(cc1)C(=O)Cn2nnc(n2)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F03 compound treatment 0.33 0.0257 2.07 0.322 0.0197 1.79 2.7299 0.9973 2078110 Maybridge3_005393 COc1cc(OC)c(nn1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F04 compound treatment 0.335 0.0308 2.48 0.324 0.0217 1.97 3.1429 0.9935 2078111 Maybridge3_005394 CCCc1c(C)nc(SCC(=O)C(C)(C)C)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F05 compound treatment 0.33 0.0257 2.07 0.332 0.0297 2.69 3.3717 0.9916 1197747 Maybridge3_005395 CCc1c(O)nc2sc3cc(OC)ccc3n2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F06 compound treatment 0.329 0.0248 1.99 0.329 0.0267 2.42 3.1222 0.9953 2078112 Maybridge3_005396 COCc1nc(SC)nc(O)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F07 compound treatment 0.335 0.0308 2.48 0.323 0.0207 1.88 3.0788 0.9907 1137263 Maybridge3_005397 Oc1cc(c2ccccc2)n(c3ccccc3)c(=O)c1S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F08 compound treatment 0.357 0.0527 4.25 0.341 0.0387 3.51 5.4868 0.9955 2078113 Maybridge3_005398 CN(C)C(=O)Oc1cc(nc(n1)C2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F09 compound treatment 0.344 0.0398 3.2 0.333 0.0307 2.79 4.2331 0.9976 1556741 Maybridge3_005399 Clc1cc2[nH]cc(c3nnnn3c4ccccc4)c2cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F10 compound treatment 0.328 0.0238 1.91 0.321 0.0187 1.7 2.5518 0.9982 1631105 Maybridge3_005400 CC(C)CCc1c(C)nc(NC(=O)C)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F11 compound treatment 0.328 0.0238 1.91 0.318 0.0157 1.42 2.3592 0.9894 2078114 Maybridge3_005401 COc1ccc(cc1)C2C/C(=N/O)/C(C)C(N2)c3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F12 compound treatment 0.326 0.0217 1.75 0.314 0.0117 1.06 1.9886 0.9712 2078115 Maybridge3_005402 COCc1nc(SCC(=O)C(C)(C)C)nc(O)c1CC(=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F13 compound treatment 0.316 0.0118 0.95 0.316 0.0137 1.24 1.5476 0.991 1006417 Maybridge3_005403 N#CC(Cc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F14 compound treatment 0.319 0.0147 1.19 0.319 0.0167 1.51 1.911 0.9928 2078116 Maybridge3_005404 CC(=C)Cc1c(C)nn(c1O)S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F15 compound treatment 0.326 0.0217 1.75 0.314 0.0117 1.06 1.9886 0.9712 2078117 Maybridge3_005405 COc1ccccc1Oc2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F16 compound treatment 0.322 0.0177 1.43 0.321 0.0187 1.7 2.2102 0.9964 2078118 Maybridge3_005406 Cc1ccc(Cn2nnc(n2)c3cc(Cl)cc(Cl)c3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F17 compound treatment 0.333 0.0288 2.32 0.322 0.0197 1.79 2.9007 0.9918 1666967 Maybridge3_005407 CC(C)C1OCc2cnc(C)c(O)c2CO1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F18 compound treatment 0.334 0.0297 2.4 0.316 0.0137 1.24 2.5725 0.9533 2078119 Maybridge3_005408 Cc1ccc(Cc2nn[nH]n2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F19 compound treatment 0.327 0.0227 1.83 0.326 0.0237 2.15 2.8158 0.9968 1222962 Maybridge3_005409 CC(O)C(Nc1ccccc1CC(=O)OC(C)(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F20 compound treatment 0.319 0.0147 1.19 0.318 0.0157 1.42 1.8468 0.9959 2078120 Maybridge3_005410 CCc1cccc(C)c1N(C(=O)C)C2=NCCC(=O)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F21 compound treatment 0.337 0.0328 2.64 0.327 0.0247 2.24 3.4494 0.9967 2078121 Maybridge3_005411 CCN(CC)C(=O)Oc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F22 compound treatment 0.331 0.0267 2.15 0.318 0.0157 1.42 2.5301 0.9798 2078122 Maybridge3_005412 COCc1nc(nc(O)c1CC2CC2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F23 mock treatment 0.301 -0.00325 -0.26 0.302 -3.12E-4 -0.03 -0.2051 -0.7792 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 F24 positive control 0.088 -0.216 -17.41 0.093 -0.209 -19.0 -25.7482 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G01 compound treatment 0.315 0.0107 0.87 0.321 0.0187 1.7 1.8116 0.9513 1921432 Maybridge3_005413 COc1ccccc1NC(=O)/C=C/c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G02 compound treatment 0.328 0.0238 1.91 0.319 0.0167 1.51 2.4234 0.9933 2078123 Maybridge3_005414 C/C(=N\O)/c1c(O)cc(c2ccccc2)n(c3ccccc3)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G03 compound treatment 0.328 0.0238 1.91 0.319 0.0167 1.51 2.4234 0.9933 2078124 Maybridge3_005415 COc1ccc(Oc2ncccc2NC(=O)c3ccco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G04 compound treatment 0.326 0.0217 1.75 0.324 0.0217 1.97 2.6305 0.9983 2078125 Maybridge3_005416 OC(=O)CSCCc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G05 compound treatment 0.346 0.0418 3.36 0.336 0.0337 3.06 4.5395 0.9989 1559760 Maybridge3_005417 COc1ccc(cc1)S(=O)(=O)Nc2ncccc2OCc3cc(F)cc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G06 compound treatment 0.348 0.0437 3.52 0.337 0.0347 3.15 4.7176 0.9984 1620309 Maybridge3_005418 CC(C)(C)NC(=O)c1cccc2-c3ccccc3C(=O)c21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G07 compound treatment 0.332 0.0278 2.23 0.32 0.0177 1.61 2.7154 0.9868 1592388 Maybridge3_005419 COc1ccc2nc(cc(O)c2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G08 compound treatment 0.294 -0.0103 -0.83 0.295 -0.00731 -0.66 -1.053 -0.9942 1478003 Maybridge3_005420 CC1(C)CC(CC(C)(C)N1)Nc2ccc(Nc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G09 compound treatment 0.346 0.0418 3.36 0.332 0.0297 2.69 4.2828 0.994 1711358 Maybridge3_005421 CC(C)c1ccc2[nH]c(C)c(CC(=O)O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G10 compound treatment 0.322 0.0177 1.43 0.324 0.0217 1.97 2.4027 0.9876 1707121 Maybridge3_005422 NC(=O)c1cn(C2CCCCC2)c3ccccc3c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G11 compound treatment 0.311 0.00675 0.54 0.312 0.00969 0.88 1.0061 0.9733 2078126 Maybridge3_005423 Nc1ccc(SCc2ccccc2)c(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G12 compound treatment 0.327 0.0227 1.83 0.315 0.0127 1.15 2.1098 0.975 1377868 Maybridge3_005424 O=S(=O)(NCc1ccccc1)C2CCS(=O)(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G13 compound treatment 0.328 0.0238 1.91 0.325 0.0227 2.06 2.8085 0.9993 1673408 Maybridge3_005425 COc1nc(C)cc(C)c1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G14 compound treatment 0.322 0.0177 1.43 0.317 0.0147 1.33 1.9534 0.9994 1158878 Maybridge3_005426 OC(=O)CNC(=O)CSc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G15 compound treatment 0.323 0.0187 1.51 0.321 0.0187 1.7 2.2671 0.9983 2078127 Maybridge3_005427 CC(=O)Nc1ccc(Cl)cc1C(=O)OCC(=O)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G16 compound treatment 0.305 7.5E-4 0.06 0.316 0.0137 1.24 0.9212 0.7406 2078128 Maybridge3_005428 CC(C)SCC(=O)Nc1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G17 compound treatment 0.322 0.0177 1.43 0.319 0.0167 1.51 2.0818 0.9996 1686101 Maybridge3_005429 Cc1oc2cc(O)cc(O)c2c(=O)c1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G18 compound treatment 0.327 0.0227 1.83 0.313 0.0107 0.97 1.9814 0.9558 2078129 Maybridge3_005430 NC(=O)c1ccc(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G19 compound treatment 0.322 0.0177 1.43 0.329 0.0267 2.42 2.7236 0.9683 1139456 Maybridge3_005431 OC(=O)CN1C(=O)CC(Sc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G20 compound treatment 0.309 0.00475 0.38 0.311 0.00869 0.79 0.8281 0.9448 1735473 Maybridge3_005432 COc1ccccc1C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G21 compound treatment 0.324 0.0198 1.59 0.32 0.0177 1.61 2.2599 1.0 2078130 Maybridge3_005433 OCC(O)C(O)C(O)C(=O)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G22 compound treatment 0.314 0.00975 0.79 0.312 0.00969 0.88 1.177 0.9984 1254465 Maybridge3_005434 O=C(NC1CCN(Cc2ccccc2)CC1)C3CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G23 mock treatment 0.304 -2.5E-4 -0.02 0.299 -0.00331 -0.3 -0.2268 -0.7528 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 G24 positive control 0.089 -0.215 -17.33 0.095 -0.207 -18.82 -25.5629 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H01 compound treatment 0.328 0.0238 1.91 0.327 0.0247 2.24 2.9369 0.9969 1295043 Maybridge3_005435 CCc1c(O)c2ccccc2n(C)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H02 compound treatment 0.34 0.0357 2.88 0.325 0.0227 2.06 3.4918 0.9865 1351100 Maybridge3_005436 Clc1ccc(cc1Cl)C(=O)Cn2nnc(n2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H03 compound treatment 0.327 0.0227 1.83 0.319 0.0167 1.51 2.3665 0.9955 1248478 Maybridge3_005437 Cc1ccc(Nc2ccccc2)nn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H04 compound treatment 0.339 0.0348 2.8 0.328 0.0257 2.33 3.6274 0.9959 2078131 Maybridge3_005438 CN(C)C(=O)Oc1cc(C)nc(SCC(=O)C(C)(C)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H05 compound treatment 0.325 0.0208 1.67 0.323 0.0207 1.88 2.5094 0.9983 1442972 Maybridge3_005439 Cc1c(O)[nH]c2n(ncc2c1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H06 compound treatment 0.329 0.0248 1.99 0.325 0.0227 2.06 2.8655 0.9999 1248545 Maybridge3_005440 CSc1ccccc1Nc2ncnc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H07 compound treatment 0.327 0.0227 1.83 0.314 0.0117 1.06 2.0456 0.9663 1342353 Maybridge3_005441 CN(C)C(=S)Sc1c(O)c2ccccc2n(C)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H08 compound treatment 0.33 0.0257 2.07 0.318 0.0157 1.42 2.4731 0.9832 2078132 Maybridge3_005442 CN(C)C(=O)Oc1cc(nc(n1)C2CC2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H09 compound treatment 0.327 0.0227 1.83 0.323 0.0207 1.88 2.6232 0.9999 2078133 Maybridge3_005443 O=S1(=O)N=S(c2ccccc21)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H10 compound treatment 0.331 0.0267 2.15 0.326 0.0237 2.15 3.0436 1.0 2078134 Maybridge3_005444 Cc1cc(Br)ccc1Nc2ncnc(n2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H11 compound treatment 0.322 0.0177 1.43 0.317 0.0147 1.33 1.9534 0.9994 1615119 Maybridge3_005445 CC(C)C1(O)c2ccccc2-c3ncccc31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H12 compound treatment 0.348 0.0437 3.52 0.334 0.0317 2.88 4.525 0.9949 2078135 Maybridge3_005446 CN(C)C(=O)Oc1cc(nc(n1)c2ccc(C)c(Cl)c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H13 compound treatment 0.33 0.0257 2.07 0.329 0.0267 2.42 3.1792 0.997 2078136 Maybridge3_005447 N#CC1(CC1)c2ccccc2C3(CC3)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H14 compound treatment 0.334 0.0297 2.4 0.336 0.0337 3.06 3.8562 0.9927 2078137 Maybridge3_005448 COCc1cc(OC(C)C)nc(n1)c2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H15 compound treatment 0.328 0.0238 1.91 0.331 0.0287 2.6 3.1937 0.9885 1438947 Maybridge3_005449 C(Cc1ccc(OCc2ccccc2)cc1)C3OCCO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H16 compound treatment 0.319 0.0147 1.19 0.318 0.0157 1.42 1.8468 0.9959 2078138 Maybridge3_005450 Clc1cc(Cl)cc(c1)c2nnn(CC(=O)c3ccc4ccccc4c3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H17 compound treatment 0.328 0.0238 1.91 0.336 0.0337 3.06 3.5146 0.9745 1068086 Maybridge3_005451 O=C(NCCc1c[nH]c2ccccc12)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H18 compound treatment 0.323 0.0187 1.51 0.314 0.0117 1.06 1.8178 0.9851 1458941 Maybridge3_005452 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H19 compound treatment 0.328 0.0238 1.91 0.308 0.00569 0.52 1.7174 0.867 2078139 Maybridge3_005453 NC(=O)c1c(/N=C/c2ccccc2Cl)sc3CCCCc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H20 compound treatment 0.323 0.0187 1.51 0.326 0.0237 2.15 2.588 0.985 2078140 Maybridge3_005454 CCc1cccc(C)c1N(C(=O)c2ccco2)C3=NCCC(=O)S3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H21 compound treatment 0.33 0.0257 2.07 0.325 0.0227 2.06 2.9224 1.0 1338065 Maybridge3_005455 Cc1c(Cc2c(F)cccc2Cl)c(=O)oc3cc(O)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H22 compound treatment 0.341 0.0367 2.96 0.339 0.0367 3.33 4.4474 0.9983 1538410 Maybridge3_005456 CN(C)C(=O)Oc1ccc2c(C)c(Cc3ccc(F)cc3)c(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H23 mock treatment 0.305 7.5E-4 0.06 0.302 -3.12E-4 -0.03 0.0226 0.3394 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 H24 positive control 0.089 -0.215 -17.33 0.097 -0.205 -18.64 -25.4345 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I01 compound treatment 0.331 0.0267 2.15 0.337 0.0347 3.15 3.7496 0.9829 1144487 Maybridge3_005457 COc1ccc(Oc2ncccc2NC(=O)c3ccc(C)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I02 compound treatment 0.322 0.0177 1.43 0.315 0.0127 1.15 1.825 0.9943 2078141 Maybridge3_005458 O=C(N1C=Cc2ccccc2C1C#N)C3=CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I03 compound treatment 0.337 0.0328 2.64 0.329 0.0267 2.42 3.5778 0.9991 1306223 Maybridge3_005459 CC(=O)N1CCC(CC1)c2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I04 compound treatment 0.328 0.0238 1.91 0.322 0.0197 1.79 2.616 0.9994 2078142 Maybridge3_005460 OC(Cn1cncn1)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I05 compound treatment 0.344 0.0398 3.2 0.335 0.0327 2.97 4.3614 0.9993 1710402 Maybridge3_005461 Fc1cc(F)cc(COc2cccnc2NS(=O)(=O)c3cccc(Cl)c3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I06 compound treatment 0.331 0.0267 2.15 0.325 0.0227 2.06 2.9794 0.9997 1004100 Maybridge3_005462 CC(=O)Nc1ccc(cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I07 compound treatment 0.33 0.0257 2.07 0.318 0.0157 1.42 2.4731 0.9832 1124590 Maybridge3_005463 Cc1ccc(Sc2ncccc2NC(=O)C3CC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I08 compound treatment 0.343 0.0388 3.12 0.329 0.0267 2.42 3.9194 0.9922 2078143 Maybridge3_005464 COC(=O)/C(=C/C(=O)c1ccc(Cl)cc1)/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I09 compound treatment 0.321 0.0168 1.35 0.327 0.0247 2.24 2.5383 0.9705 1557900 Maybridge3_005465 COc1ccc(cc1)C(=O)Nc2cccnc2Sc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I10 compound treatment 0.344 0.0398 3.2 0.341 0.0387 3.51 4.7466 0.9989 1558318 Maybridge3_005466 C=CCCN1C(=O)CN=C(c2ccccc2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I11 compound treatment 0.343 0.0388 3.12 0.329 0.0267 2.42 3.9194 0.9922 2078144 Maybridge3_005467 Cc1nc(sc1c2ccnc(N)n2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I12 compound treatment 0.374 0.0698 5.62 0.385 0.0827 7.51 9.2789 0.9898 2078145 Maybridge3_005468 O=C(/C(=C/1\Nc2ccccc2S1)/C#N)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I13 compound treatment 0.324 0.0198 1.59 0.326 0.0237 2.15 2.645 0.989 1162575 Maybridge3_005469 COc1nc(C)cc(C)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I14 compound treatment 0.323 0.0187 1.51 0.324 0.0217 1.97 2.4597 0.9914 1029435 Maybridge3_005470 NC(=O)CNC(=O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I15 compound treatment 0.345 0.0408 3.28 0.346 0.0437 3.97 5.1244 0.9956 2078146 Maybridge3_005471 COc1ccccc1/C=C/2\Cc3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I16 compound treatment 0.325 0.0208 1.67 0.312 0.00969 0.88 1.8033 0.9551 2078147 Maybridge3_005472 CCOC(=O)Cc1csc(NC(=O)C/C=C/C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I17 compound treatment 0.317 0.0127 1.03 0.332 0.0297 2.69 2.6315 0.9125 2078148 Maybridge3_005473 COc1ccc(cc1)C(=O)Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I18 compound treatment 0.327 0.0227 1.83 0.329 0.0267 2.42 3.0083 0.9905 2078149 Maybridge3_005474 CC(=O)Nc1cccc(Oc2c(F)c(F)c(F)c(F)c2F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I19 compound treatment 0.335 0.0308 2.48 0.323 0.0207 1.88 3.0788 0.9907 1311180 Maybridge3_005475 O=C1CC(c2ccccc2)S(=O)(=O)c3ccccc3N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I20 compound treatment 0.317 0.0127 1.03 0.319 0.0167 1.51 1.7971 0.9821 1220868 Maybridge3_005476 O=C(NC1CCN(Cc2ccc3ccccc3c2)CC1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I21 compound treatment 0.321 0.0168 1.35 0.324 0.0217 1.97 2.3458 0.983 1045701 Maybridge3_005477 OC1CC(Oc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I22 compound treatment 0.321 0.0168 1.35 0.315 0.0127 1.15 1.7681 0.9969 1258566 Maybridge3_005478 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I23 mock treatment 0.307 0.00275 0.22 0.307 0.00469 0.43 0.4575 0.9537 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 I24 positive control 0.09 -0.214 -17.25 0.096 -0.206 -18.73 -25.4418 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J01 compound treatment 0.339 0.0348 2.8 0.343 0.0407 3.69 4.5902 0.9906 2078150 Maybridge3_005479 CCOc1ccc(cc1)C(=O)/C=C/C(=O)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J02 compound treatment 0.321 0.0168 1.35 0.318 0.0157 1.42 1.9607 0.9996 1238462 Maybridge3_005480 Clc1cccc(Cl)c1Cn2nnc(n2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J03 compound treatment 0.326 0.0217 1.75 0.32 0.0177 1.61 2.3737 0.9991 1438952 Maybridge3_005481 N(c1ccccc1)c2ccc(nn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J04 compound treatment 0.333 0.0288 2.32 0.321 0.0187 1.7 2.8365 0.9883 1291127 Maybridge3_005482 CC(C)(C)C(=O)Cn1nnc(n1)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J05 compound treatment 0.326 0.0217 1.75 0.322 0.0197 1.79 2.5021 0.9999 1212941 Maybridge3_005483 CCCCc1c(O)nc2sc3ccccc3n2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J06 compound treatment 0.346 0.0418 3.36 0.329 0.0267 2.42 4.0902 0.9871 2078151 Maybridge3_005484 COCc1cc(OC(=O)N(C)C)nc(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J07 compound treatment 0.367 0.0628 5.05 0.35 0.0477 4.33 6.6339 0.997 2078152 Maybridge3_005485 COC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccccc3C(F)(F)F)C(=O)OC)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J08 compound treatment 0.323 0.0187 1.51 0.324 0.0217 1.97 2.4597 0.9914 2078153 Maybridge3_005486 Cc1cc(O)nc(n1)c2ccc(cc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J09 compound treatment 0.328 0.0238 1.91 0.323 0.0207 1.88 2.6802 1.0 1202036 Maybridge3_005487 NS(=O)(=O)c1ccccc1Sc2ccccc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J10 compound treatment 0.324 0.0198 1.59 0.321 0.0187 1.7 2.324 0.9995 1716332 Maybridge3_005488 CC(=C)Cc1c(C)nc(N)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J11 compound treatment 0.32 0.0158 1.27 0.324 0.0217 1.97 2.2888 0.9774 2078154 Maybridge3_005489 CCCC/1C(NC(C\C1=N\O)c2ccco2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J12 compound treatment 0.318 0.0138 1.11 0.316 0.0137 1.24 1.6615 0.9983 2078155 Maybridge3_005490 Cc1ccc(cc1Cl)c2nnn(CC(=O)C(C)(C)C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J13 compound treatment 0.314 0.00975 0.79 0.309 0.00669 0.61 0.9844 0.9919 2078156 Maybridge3_005491 COC(=O)C(Cc1ccccc1)(Cc2ccccc2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J14 compound treatment 0.322 0.0177 1.43 0.319 0.0167 1.51 2.0818 0.9996 2078157 Maybridge3_005492 CCCCc1c(O)nc(nc1COC)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J15 compound treatment 0.325 0.0208 1.67 0.326 0.0237 2.15 2.7019 0.9922 2078158 Maybridge3_005493 CC(=O)Oc1c(C)c(C)c2oc(=O)ccc2c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J16 compound treatment 0.323 0.0187 1.51 0.316 0.0137 1.24 1.9462 0.9953 2078159 Maybridge3_005494 Cn1nnc(n1)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J17 compound treatment 0.327 0.0227 1.83 0.317 0.0147 1.33 2.2381 0.9878 1532186 Maybridge3_005495 O=C1COc2ccccc2N1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J18 compound treatment 0.328 0.0238 1.91 0.312 0.00969 0.88 1.9741 0.9378 2078160 Maybridge3_005496 CCCc1cc(O)nc(n1)c2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J19 compound treatment 0.329 0.0248 1.99 0.326 0.0237 2.15 2.9297 0.9993 2078161 Maybridge3_005497 CN(C)/C=C\c1ccnc(c1)c2cc(/C=C\N(C)C)ccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J20 compound treatment 0.329 0.0248 1.99 0.327 0.0247 2.24 2.9939 0.9983 2078162 Maybridge3_005498 Fc1cccc(NC2=NCCCC(=O)S2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J21 compound treatment 0.631 0.327 26.31 0.609 0.307 27.84 38.2902 0.9996 2078163 Maybridge3_005499 Oc1cc2oc(=O)cc(c2cc1Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J22 compound treatment 0.337 0.0328 2.64 0.331 0.0287 2.6 3.7061 1.0 2078164 Maybridge3_005500 CCCc1nc(SCC(=O)c2ccc(Cl)cc2)nc(OC(=O)N(C)C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J23 mock treatment 0.307 0.00275 0.22 0.3 -0.00231 -0.21 0.0082 0.0267 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 J24 positive control 0.09 -0.214 -17.25 0.096 -0.206 -18.73 -25.4418 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K01 compound treatment 0.339 0.0348 2.8 0.337 0.0347 3.15 4.2051 0.9983 2078165 Maybridge3_005501 COc1ccc(Oc2ncccc2NC(=O)c3ccccc3C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K02 compound treatment 0.32 0.0158 1.27 0.318 0.0157 1.42 1.9037 0.9983 2078166 Maybridge3_005502 CCCc1ccc(nc1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K03 compound treatment 0.299 -0.00525 -0.42 0.292 -0.0103 -0.94 -0.9608 -0.9355 1198835 Maybridge3_005503 NCCNc1cc(nc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K04 compound treatment 0.303 -0.00125 -0.1 0.287 -0.0153 -1.39 -1.054 -0.7563 1572113 Maybridge3_005504 Cc1ccc(cc1)C(=O)OCC2OC(CC2OC(=O)c3ccc(C)cc3)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K05 compound treatment 0.32 0.0158 1.27 0.312 0.00969 0.88 1.5186 0.984 1597421 Maybridge3_005505 Cc1ccc(Sc2ncccc2NC(=O)c3ccc(C)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K06 compound treatment 0.35 0.0457 3.68 0.344 0.0417 3.78 5.2808 0.9999 1723862 Maybridge3_005506 Clc1ccc2n(CN3CCOCC3)c4ccccc4c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K07 compound treatment 0.324 0.0198 1.59 0.308 0.00569 0.52 1.4896 0.8909 1199418 Maybridge3_005507 Cc1ccc(Sc2ncccc2NC(=O)Cc3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K08 compound treatment 0.325 0.0208 1.67 0.306 0.00369 0.33 1.4182 0.8322 1276282 Maybridge3_005508 CNC(=O)c1ccccc1Sc2ccc(OC)cc2C(=O)NC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K09 compound treatment 0.32 0.0158 1.27 0.313 0.0107 0.97 1.5828 0.9912 1130288 Maybridge3_005509 NC(=O)c1ccccc1NC(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K10 compound treatment 0.312 0.00775 0.62 0.307 0.00469 0.43 0.7422 0.9826 1262977 Maybridge3_005510 CCCCC1(O)CCN(Cc2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K11 compound treatment 0.326 0.0217 1.75 0.322 0.0197 1.79 2.5021 0.9999 2078167 Maybridge3_005511 Cc1cc(N2CCN(CC2)C(=O)/C=C/C(=O)O)c3ccccc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K12 compound treatment 0.323 0.0187 1.51 0.317 0.0147 1.33 2.0104 0.9981 1732918 Maybridge3_005512 O=S1(=O)CC(CS(=O)(=O)C1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K13 compound treatment 0.322 0.0177 1.43 0.315 0.0127 1.15 1.825 0.9943 2078168 Maybridge3_005513 OCCNc1nc2ccccc2nc1NCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K14 compound treatment 0.31 0.00575 0.46 0.304 0.00169 0.15 0.4357 0.8934 1413105 Maybridge3_005514 C(Sc1ccccn1)c2cccc(CSc3ccccn3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K15 compound treatment 0.332 0.0278 2.23 0.321 0.0187 1.7 2.7796 0.9908 1732657 Maybridge3_005515 NC(=O)c1cccc2cccc(Sc3ccccc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K16 compound treatment 0.325 0.0208 1.67 0.318 0.0157 1.42 2.1884 0.9968 1146462 Maybridge3_005516 CCOC(=O)c1ccc(NC(=O)CSc2nccn2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K17 compound treatment 0.311 0.00675 0.54 0.311 0.00869 0.79 0.942 0.9835 1624690 Maybridge3_005517 OC(COc1ccc(F)cc1)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K18 compound treatment 0.324 0.0198 1.59 0.326 0.0237 2.15 2.645 0.989 1312048 Maybridge3_005518 CC(C)(C)NS(=O)(=O)C1CCS(=O)(=O)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K19 compound treatment 0.321 0.0168 1.35 0.324 0.0217 1.97 2.3458 0.983 1731529 Maybridge3_005519 CN1CC(Oc2ccccc2C1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K20 compound treatment 0.325 0.0208 1.67 0.319 0.0167 1.51 2.2526 0.9988 1425842 Maybridge3_005520 O=C(NC1CCN(CC1)C(=O)C2CCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K21 compound treatment 0.324 0.0198 1.59 0.318 0.0157 1.42 2.1315 0.9985 2078169 Maybridge3_005521 O=C1CC(c2ccccc2)S(=O)(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K22 compound treatment 0.316 0.0118 0.95 0.307 0.00469 0.43 0.9699 0.9349 1588419 Maybridge3_005522 Cc1cc(c(C)cc1Cl)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K23 mock treatment 0.304 -2.5E-4 -0.02 0.301 -0.00131 -0.12 -0.0985 -0.815 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 K24 positive control 0.092 -0.212 -17.09 0.098 -0.204 -18.55 -25.1995 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L01 compound treatment 0.311 0.00675 0.54 0.313 0.0107 0.97 1.0703 0.9625 2078170 Maybridge3_005523 Oc1ccc(Br)cc1CNc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L02 compound treatment 0.329 0.0248 1.99 0.322 0.0197 1.79 2.6729 0.9985 1535928 Maybridge3_005524 Fc1cccc(Cn2nnc(n2)N3CCCCC3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L03 compound treatment 0.347 0.0428 3.44 0.335 0.0327 2.97 4.5323 0.9973 1300241 Maybridge3_005525 COc1cccc(Nc2ccc(nn2)c3ccccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L04 compound treatment 0.352 0.0478 3.85 0.339 0.0367 3.33 5.0737 0.9974 2078171 Maybridge3_005526 CN(C)C(=O)Oc1nc(nc(C)c1CC=C)c2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L05 compound treatment 0.326 0.0217 1.75 0.322 0.0197 1.79 2.5021 0.9999 1136104 Maybridge3_005527 Cn1c(=O)c(Sc2ccccc2)c(O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L06 compound treatment 0.347 0.0428 3.44 0.335 0.0327 2.97 4.5323 0.9973 2078172 Maybridge3_005528 CN(C)C(=O)Sc1nnc(C2CC2)n1c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L07 compound treatment 0.316 0.0118 0.95 0.316 0.0137 1.24 1.5476 0.991 2078173 Maybridge3_005529 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccc(o2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L08 compound treatment 0.326 0.0217 1.75 0.327 0.0247 2.24 2.823 0.9926 1161217 Maybridge3_005530 COCc1cc(O)nc(NC(=O)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L09 compound treatment 0.332 0.0278 2.23 0.328 0.0257 2.33 3.2289 0.9998 2078174 Maybridge3_005531 COC(=O)c1ccccc1S2=NS(=O)(=O)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L10 compound treatment 0.328 0.0238 1.91 0.321 0.0187 1.7 2.5518 0.9982 2078175 Maybridge3_005532 COCc1nc(SC)nc(O)c1CC(=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L11 compound treatment 0.32 0.0158 1.27 0.314 0.0117 1.06 1.647 0.9961 1430946 Maybridge3_005533 CC1C(O)CC(NC1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L12 compound treatment 0.313 0.00875 0.7 0.313 0.0107 0.97 1.1842 0.9877 2078176 Maybridge3_005534 Fc1cccc(Cl)c1Cn2nnc(n2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L13 compound treatment 0.319 0.0147 1.19 0.32 0.0177 1.61 1.9752 0.989 2078177 Maybridge3_005535 ClC1(Cl)CC1OC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L14 compound treatment 0.311 0.00675 0.54 0.305 0.00269 0.24 0.5568 0.9346 2078178 Maybridge3_005536 CC(C)[n+]1c(C)csc1Nc2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L15 compound treatment 0.175 -0.129 -10.41 0.177 -0.125 -11.37 -15.4028 -0.999 2078179 Maybridge3_005537 CC(=O)Oc1cccc2C(=O)C=CC(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L16 compound treatment 0.315 0.0107 0.87 0.312 0.00969 0.88 1.2339 1.0 2078180 Maybridge3_005538 CCn1nnc(n1)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L17 compound treatment 0.313 0.00875 0.7 0.316 0.0137 1.24 1.3768 0.9639 1669414 Maybridge3_005539 Clc1ccc(cc1)C(=O)N2C(=O)COc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L18 compound treatment 0.324 0.0198 1.59 0.321 0.0187 1.7 2.324 0.9995 2078181 Maybridge3_005540 CCCc1nc(SC)nc(O)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L19 compound treatment 0.327 0.0227 1.83 0.328 0.0257 2.33 2.9442 0.9929 1650332 Maybridge3_005541 CCOC(=O)C(C(=O)O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L20 compound treatment 0.323 0.0187 1.51 0.326 0.0237 2.15 2.588 0.985 1262370 Maybridge3_005542 C(C1CC1)n2nnc(n2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L21 compound treatment 0.325 0.0208 1.67 0.318 0.0157 1.42 2.1884 0.9968 2078182 Maybridge3_005543 Cc1nnc(Nc2cccc(F)c2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L22 compound treatment 0.325 0.0208 1.67 0.326 0.0237 2.15 2.7019 0.9922 1387562 Maybridge3_005544 CC(C)(C)C(=O)Cn1nnc(n1)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L23 mock treatment 0.306 0.00175 0.14 0.307 0.00469 0.43 0.4005 0.8936 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 L24 positive control 0.091 -0.213 -17.17 0.097 -0.205 -18.64 -25.3206 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M01 compound treatment 0.35 0.0457 3.68 0.347 0.0447 4.06 5.4733 0.9988 2078183 Maybridge3_005545 COc1ccc(Oc2ncccc2NC(=O)c3ccc(OC(F)(F)F)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M02 compound treatment 0.39 0.0858 6.91 0.364 0.0617 5.6 8.8421 0.9946 2078184 Maybridge3_005546 COC(=O)/C=C\1/OC(=CC1=O)c2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M03 compound treatment 0.338 0.0338 2.72 0.332 0.0297 2.69 3.8272 1.0 2078185 Maybridge3_005547 Oc1nc(nc2ccccc12)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M04 compound treatment 0.322 0.0177 1.43 0.317 0.0147 1.33 1.9534 0.9994 1346725 Maybridge3_005548 CCc1c(O)c2ccccc2[nH]c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M05 compound treatment 0.32 0.0158 1.27 0.317 0.0147 1.33 1.8395 0.9997 1384414 Maybridge3_005549 Cc1ccc(Sc2ncccc2NC(=O)c3ccco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M06 compound treatment 0.32 0.0158 1.27 0.314 0.0117 1.06 1.647 0.9961 1380766 Maybridge3_005550 Fc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M07 compound treatment 0.335 0.0308 2.48 0.328 0.0257 2.33 3.3997 0.9995 1157232 Maybridge3_005551 Cn1c(Cn2c3ccccc3c4ccccc24)nnc1SCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M08 compound treatment 0.323 0.0187 1.51 0.319 0.0167 1.51 2.1387 1.0 1418277 Maybridge3_005552 OCc1ccccc1Sc2ccc(Cl)cc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M09 compound treatment 0.314 0.00975 0.79 0.312 0.00969 0.88 1.177 0.9984 1547625 Maybridge3_005553 Cc1cc(N2CCN(CC2)C(=O)c3ccco3)c4ccccc4n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M10 compound treatment 0.309 0.00475 0.38 0.315 0.0127 1.15 1.0848 0.8939 1549124 Maybridge3_005554 COC(=O)c1ccccc1S(=O)(=O)N2CCc3[nH]c4ccc(F)cc4c3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M11 compound treatment 0.314 0.00975 0.79 0.307 0.00469 0.43 0.856 0.9586 2078186 Maybridge3_005555 CC(C)(C)OC(=O)n1ccc2cc(Br)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M12 compound treatment 0.335 0.0308 2.48 0.336 0.0337 3.06 3.9132 0.9945 2078187 Maybridge3_005556 CC(=O)Oc1ccc(cc1)C2NC(CS2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M13 compound treatment 0.314 0.00975 0.79 0.319 0.0167 1.51 1.6263 0.9532 1269607 Maybridge3_005557 O=C(Nc1nnc(s1)C2CC2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M14 compound treatment 0.321 0.0168 1.35 0.318 0.0157 1.42 1.9607 0.9996 1331915 Maybridge3_005558 CCSc1ccc(cc1)C(=O)NCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M15 compound treatment 0.461 0.157 12.62 0.443 0.141 12.77 17.9555 1.0 2078188 Maybridge3_005559 COc1cc(/C=C/2\Cc3ccccc3C2=O)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M16 compound treatment 0.313 0.00875 0.7 0.316 0.0137 1.24 1.3768 0.9639 1145220 Maybridge3_005560 OCCOc1ccc(C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M17 compound treatment 0.305 7.5E-4 0.06 0.309 0.00669 0.61 0.4719 0.7736 2078189 Maybridge3_005561 CC(C)C(N)C(O)(c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M18 compound treatment 0.321 0.0168 1.35 0.315 0.0127 1.15 1.7681 0.9969 2078190 Maybridge3_005562 C/C(=N\O)/c1ccc(OC(=O)c2ccc(Br)o2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M19 compound treatment 0.355 0.0508 4.09 0.358 0.0557 5.05 6.4641 0.9944 1150780 Maybridge3_005563 NC(=O)COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M20 compound treatment 0.315 0.0107 0.87 0.312 0.00969 0.88 1.2339 1.0 1198975 Maybridge3_005564 O=C(NC1CCN(CC1)C(=O)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M21 compound treatment 0.321 0.0168 1.35 0.316 0.0137 1.24 1.8323 0.9992 1075344 Maybridge3_005565 CCNc1nc(NC(C)C)nc(SC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M22 compound treatment 0.315 0.0107 0.87 0.31 0.00769 0.7 1.1055 0.9943 1339230 Maybridge3_005566 O=S(=O)(NC1CCN(Cc2ccccc2)CC1)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M23 mock treatment 0.303 -0.00125 -0.1 0.3 -0.00231 -0.21 -0.2196 -0.9433 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 M24 positive control 0.092 -0.212 -17.09 0.097 -0.205 -18.64 -25.2637 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N01 compound treatment 0.399 0.0948 7.63 0.391 0.0887 8.05 11.0876 0.9996 1377737 Maybridge3_005567 Cc1ccc(SC(CC(=O)c2ccc(C)cc2)C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N02 compound treatment 0.324 0.0198 1.59 0.324 0.0217 1.97 2.5166 0.9944 1428151 Maybridge3_005568 Clc1ccc(Cn2nnc(n2)N3CCCCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N03 compound treatment 0.322 0.0177 1.43 0.321 0.0187 1.7 2.2102 0.9964 2078191 Maybridge3_005569 CC1(C)CC(=C(Sc2ccccc2)C(=O)C1)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N04 compound treatment 0.321 0.0168 1.35 0.317 0.0147 1.33 1.8965 1.0 1510914 Maybridge3_005570 Cc1nc(nc(O)c1CC2CC2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N05 compound treatment 0.324 0.0198 1.59 0.316 0.0137 1.24 2.0031 0.9925 1166245 Maybridge3_005571 Oc1nc2sc3ccccc3n2c(=O)c1c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N06 compound treatment 0.351 0.0468 3.76 0.341 0.0387 3.51 5.1451 0.9994 2078192 Maybridge3_005572 CCN(CC)C(=O)Oc1cc(COC)nc(n1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N07 compound treatment 0.324 0.0198 1.59 0.313 0.0107 0.97 1.8106 0.9719 1207911 Maybridge3_005573 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccc(O)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N08 compound treatment 0.328 0.0238 1.91 0.321 0.0187 1.7 2.5518 0.9982 2078193 Maybridge3_005574 CCCCc1c(C)nc(nc1O)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N09 compound treatment 0.329 0.0248 1.99 0.319 0.0167 1.51 2.4804 0.9908 1916985 Maybridge3_005575 C/C(=N/O)/c1ccc(OCCO)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N10 compound treatment 0.326 0.0217 1.75 0.322 0.0197 1.79 2.5021 0.9999 2078194 Maybridge3_005576 CCCCc1c(O)nc(SC)nc1COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N11 compound treatment 0.323 0.0187 1.51 0.315 0.0127 1.15 1.882 0.9911 1415843 Maybridge3_005577 CCC1C(O)CC(NC1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N12 compound treatment 0.325 0.0208 1.67 0.328 0.0257 2.33 2.8303 0.9866 1400296 Maybridge3_005578 COCc1cc(=O)oc2cc(NC(=O)c3ccc(cc3)C(C)(C)C)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N13 compound treatment 0.325 0.0208 1.67 0.324 0.0217 1.97 2.5735 0.9967 2078195 Maybridge3_005579 ClC1(Cl)CC1CS(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N14 compound treatment 0.329 0.0248 1.99 0.322 0.0197 1.79 2.6729 0.9985 2078196 Maybridge3_005580 CS/C(=N\C(C)(C)C)/NCC1CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N15 compound treatment 0.32 0.0158 1.27 0.316 0.0137 1.24 1.7754 0.9999 2078197 Maybridge3_005581 COc1ccc(Oc2ccccc2OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N16 compound treatment 0.317 0.0127 1.03 0.315 0.0127 1.15 1.5403 0.9984 1650125 Maybridge3_005582 Nc1ncnc(Nc2ccc(Cl)cc2C#N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N17 compound treatment 0.311 0.00675 0.54 0.313 0.0107 0.97 1.0703 0.9625 1515750 Maybridge3_005583 CCN1CCC(O)(CC1)C#Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N18 compound treatment 0.331 0.0267 2.15 0.324 0.0217 1.97 2.9152 0.999 2078198 Maybridge3_005584 CCCc1nc(nc(O)c1C(C)C=C)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N19 compound treatment 0.326 0.0217 1.75 0.321 0.0187 1.7 2.4379 0.9999 1712018 Maybridge3_005585 CC(NCc1ccccc1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N20 compound treatment 0.322 0.0177 1.43 0.319 0.0167 1.51 2.0818 0.9996 2078199 Maybridge3_005586 Fc1ccc(NC2=NCCC(=O)S2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N21 compound treatment 0.327 0.0227 1.83 0.325 0.0227 2.06 2.7516 0.9983 1130350 Maybridge3_005587 Cc1nc(nc(O)c1CC=C)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N22 compound treatment 0.333 0.0288 2.32 0.327 0.0247 2.24 3.2216 0.9999 1249270 Maybridge3_005588 COCC(=O)Oc1ccc2c(C)c(Cc3ccc(F)cc3)c(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N23 mock treatment 0.308 0.00375 0.3 0.305 0.00269 0.24 0.386 0.9944 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 N24 positive control 0.093 -0.211 -17.01 0.097 -0.205 -18.64 -25.2067 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O01 compound treatment 0.37 0.0658 5.29 0.369 0.0667 6.05 8.0242 0.9978 2078200 Maybridge3_005589 O=C/1Nc2ccccc2C(=O)\C1=C\Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O02 compound treatment 0.333 0.0288 2.32 0.332 0.0297 2.69 3.5425 0.9971 1049683 Maybridge3_005590 N#Cc1ccc(cc1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O03 compound treatment 0.329 0.0248 1.99 0.322 0.0197 1.79 2.6729 0.9985 1353347 Maybridge3_005591 CC(C)C(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O04 compound treatment 0.325 0.0208 1.67 0.328 0.0257 2.33 2.8303 0.9866 2078201 Maybridge3_005592 OC(=O)CCc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O05 compound treatment 0.314 0.00975 0.79 0.32 0.0177 1.61 1.6904 0.9459 1585161 Maybridge3_005593 Cc1ccc(Sc2ncccc2NC(=O)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O06 compound treatment 0.448 0.144 11.58 0.452 0.15 13.59 17.7929 0.9968 1722952 Maybridge3_005594 CCC1C2=C(CCCC2=O)NC3=C1C(=O)CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O07 compound treatment 0.327 0.0227 1.83 0.32 0.0177 1.61 2.4307 0.9978 1337452 Maybridge3_005595 Clc1ccc(Sc2ncccc2NC(=O)C3CC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O08 compound treatment 0.324 0.0198 1.59 0.334 0.0317 2.88 3.1584 0.961 1610969 Maybridge3_005596 CC(=O)OCc1ccccc1Sc2ccc(Cl)cc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O09 compound treatment 0.299 -0.00525 -0.42 0.299 -0.00331 -0.3 -0.5116 -0.9861 1738371 Maybridge3_005597 C(CN1CCCCC1)Nc2cc(nc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O10 compound treatment 0.321 0.0168 1.35 0.322 0.0197 1.79 2.2174 0.9904 1703424 Maybridge3_005598 CC1(C)C2CCC1(C)C(C2)NC(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O11 compound treatment 0.345 0.0408 3.28 0.35 0.0477 4.33 5.3812 0.9907 2078202 Maybridge3_005599 FC(F)(F)c1cc(nc(OCC(=O)c2ccccc2)c1C#N)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O12 compound treatment 0.331 0.0267 2.15 0.329 0.0267 2.42 3.2361 0.9983 1514301 Maybridge3_005600 Nc1ccc(SCC(=O)O)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O13 compound treatment 0.327 0.0227 1.83 0.333 0.0307 2.79 3.2651 0.9793 1223945 Maybridge3_005601 COC(=O)CCC(=O)c1ccn(c1)S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O14 compound treatment 0.327 0.0227 1.83 0.324 0.0217 1.97 2.6874 0.9994 1134038 Maybridge3_005602 NC(=O)CNC(=O)c1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O15 compound treatment 0.418 0.114 9.16 0.44 0.138 12.5 15.3145 0.9883 2078203 Maybridge3_005603 O=C1/C(=C/c2c[nH]c3ccccc23)/COc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O16 compound treatment 0.326 0.0217 1.75 0.328 0.0257 2.33 2.8872 0.9901 1708769 Maybridge3_005604 OCCOc1ccc(cc1)C2=NCCO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O17 compound treatment 0.326 0.0217 1.75 0.326 0.0237 2.15 2.7588 0.9948 2078204 Maybridge3_005605 NC(=O)c1ccccc1Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O18 compound treatment 0.327 0.0227 1.83 0.327 0.0247 2.24 2.88 0.995 1561379 Maybridge3_005606 CSc1nnc(CCCc2nnc(SC)o2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O19 compound treatment 0.328 0.0238 1.91 0.325 0.0227 2.06 2.8085 0.9993 2078205 Maybridge3_005607 O=C(CCC(=O)c1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O20 compound treatment 0.327 0.0227 1.83 0.328 0.0257 2.33 2.9442 0.9929 1380599 Maybridge3_005608 O=C(NC1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O21 compound treatment 0.327 0.0227 1.83 0.33 0.0277 2.51 3.0725 0.9879 1031949 Maybridge3_005609 OC(=O)CCOc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O22 compound treatment 0.334 0.0297 2.4 0.333 0.0307 2.79 3.6637 0.9972 1513124 Maybridge3_005610 COc1ccc(CCNC(=O)c2ccco2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O23 mock treatment 0.31 0.00575 0.46 0.312 0.00969 0.88 0.9492 0.9551 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 O24 positive control 0.094 -0.21 -16.93 0.098 -0.204 -18.55 -25.0856 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P01 compound treatment 0.33 0.0257 2.07 0.329 0.0267 2.42 3.1792 0.997 2078206 Maybridge3_005611 COc1cc(OC)c(Br)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P02 compound treatment 0.314 0.00975 0.79 0.311 0.00869 0.79 1.1128 1.0 1567530 Maybridge3_005612 Cc1cc(Nc2cc(Cl)cc(Cl)c2)nc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P03 compound treatment 0.348 0.0437 3.52 0.337 0.0347 3.15 4.7176 0.9984 1401618 Maybridge3_005613 Cc1cccc(Nc2ccc(nn2)c3ccccc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P04 compound treatment 0.324 0.0198 1.59 0.32 0.0177 1.61 2.2599 1.0 2078207 Maybridge3_005614 COCc1cc(OC(=O)N(C)C)nc(SC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P05 compound treatment 0.318 0.0138 1.11 0.326 0.0237 2.15 2.3033 0.9524 2078208 Maybridge3_005615 C/C(=N\c1ccccc1)/c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P06 compound treatment 0.327 0.0227 1.83 0.332 0.0297 2.69 3.2009 0.9823 2078209 Maybridge3_005616 CSc1nnc(C2CC2)n1c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P07 compound treatment 0.343 0.0388 3.12 0.338 0.0357 3.24 4.4971 0.9998 1523901 Maybridge3_005617 COC(=O)C1=C(C)NC(=C(C1c2ccccc2)C(=O)OC)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P08 compound treatment 0.325 0.0208 1.67 0.326 0.0237 2.15 2.7019 0.9922 2078210 Maybridge3_005618 COCc1nc(nc(O)c1C)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P09 compound treatment 0.332 0.0278 2.23 0.334 0.0317 2.88 3.614 0.9922 1681351 Maybridge3_005619 CC(C)c1cc(O)c(c2ccccc2)c(=O)n1c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P10 compound treatment 0.319 0.0147 1.19 0.321 0.0187 1.7 2.0393 0.9848 1050551 Maybridge3_005620 CCSc1nc(N)cc(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P11 compound treatment 0.317 0.0127 1.03 0.319 0.0167 1.51 1.7971 0.9821 1446663 Maybridge3_005621 CC1C(NC(C(C)C1=O)c2ccco2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P12 compound treatment 0.328 0.0238 1.91 0.328 0.0257 2.33 3.0011 0.9952 1561669 Maybridge3_005622 COCc1cc(=O)oc2cc(NC(=O)C3CC3)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P13 compound treatment 0.317 0.0127 1.03 0.316 0.0137 1.24 1.6045 0.9955 2078211 Maybridge3_005623 N#CCOc1ccc2ccccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P14 compound treatment 0.325 0.0208 1.67 0.324 0.0217 1.97 2.5735 0.9967 2078212 Maybridge3_005624 CCC(=O)N(C1=NCCC(=O)S1)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P15 compound treatment 0.32 0.0158 1.27 0.32 0.0177 1.61 2.0321 0.9932 2078213 Maybridge3_005625 Brc1ccc(OCC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P16 compound treatment 0.32 0.0158 1.27 0.325 0.0227 2.06 2.353 0.9729 2078214 Maybridge3_005626 CCc1cc(O)nc(n1)c2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P17 compound treatment 0.33 0.0257 2.07 0.334 0.0317 2.88 3.5001 0.9871 2078215 Maybridge3_005627 COC(=O)CCC1CCC(CCC(=O)OC)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P18 compound treatment 0.326 0.0217 1.75 0.319 0.0167 1.51 2.3096 0.9974 2078216 Maybridge3_005628 CCCc1nc(nc(O)c1CC=C)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P19 compound treatment 0.323 0.0187 1.51 0.322 0.0197 1.79 2.3313 0.9965 1131627 Maybridge3_005629 CC(CO)NC(=O)OCC1c2ccccc2-c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P20 compound treatment 0.362 0.0578 4.65 0.363 0.0607 5.51 7.1836 0.9965 2078217 Maybridge3_005630 Fc1ccc(cc1Cl)N(C(=O)c2ccco2)C3=NCCC(=O)S3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P21 compound treatment 0.326 0.0217 1.75 0.322 0.0197 1.79 2.5021 0.9999 2078218 Maybridge3_005631 CN(C)C(=S)Oc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P22 compound treatment 0.328 0.0238 1.91 0.327 0.0247 2.24 2.9369 0.9969 1276434 Maybridge3_005632 COCc1cc(=O)oc2cc(OC(=O)C)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P23 mock treatment 0.308 0.00375 0.3 0.309 0.00669 0.61 0.6428 0.948 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1446 P24 positive control 0.094 -0.21 -16.93 0.1 -0.202 -18.36 -24.9573 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A01 compound treatment 0.315 0.00938 0.75 0.319 0.00325 0.3 0.7424 0.916 1345321 Maybridge3_005633 COCc1cc(=O)oc2cc(OC(=O)C)c(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A02 compound treatment 0.306 3.75E-4 0.03 0.312 -0.00375 -0.34 -0.2193 -0.6419 2078219 Maybridge3_005634 CCOC(=O)c1c(/N=C/c2ccccc2O)sc3CCCc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A03 compound treatment 0.311 0.00538 0.43 0.315 -7.5E-4 -0.07 0.2579 0.5887 2078220 Maybridge3_005635 CC1CC(CC(C)(C)C1)NC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A04 compound treatment 0.316 0.0104 0.84 0.322 0.00625 0.57 0.9919 0.9822 2078221 Maybridge3_005636 O=C(CC1OC(=O)c2ccccc12)c3ccc4ccccc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A05 compound treatment 0.311 0.00538 0.43 0.32 0.00425 0.39 0.5788 0.9984 1071883 Maybridge3_005637 COc1ccc(CCN2C(=O)CSC2=S)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A06 compound treatment 0.306 3.75E-4 0.03 0.316 2.5E-4 0.02 0.0374 0.9901 2078222 Maybridge3_005638 CSc1cccc(c1)N2C(=O)CSC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A07 compound treatment 0.3 -0.00562 -0.45 0.311 -0.00475 -0.43 -0.6252 -0.9997 2078223 Maybridge3_005639 COc1ccc(CC/N=C\2/NCCS2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A08 compound treatment 0.303 -0.00262 -0.21 0.311 -0.00475 -0.43 -0.4543 -0.9462 2078224 Maybridge3_005640 Clc1ccccc1C2OC(=O)c3ccccc3S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A09 compound treatment 0.293 -0.0126 -1.02 0.304 -0.0118 -1.07 -1.4731 -0.9997 1473832 Maybridge3_005641 COc1cccc(c1)N2C(=O)CC(Sc3ccccc3N)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A10 compound treatment 0.303 -0.00262 -0.21 0.31 -0.00575 -0.52 -0.5185 -0.9208 2078225 Maybridge3_005642 Fc1ccc(CSc2nnc(s2)c3ccncc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A11 compound treatment 0.307 0.00138 0.11 0.313 -0.00275 -0.25 -0.0982 -0.3597 2078226 Maybridge3_005643 COc1cc(OC)cc(c1)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A12 compound treatment 0.307 0.00138 0.11 0.315 -7.5E-4 -0.07 0.0302 0.232 2078227 Maybridge3_005644 CC(C)(C)c1ccc(cc1)n2nnnc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A13 compound treatment 0.311 0.00538 0.43 0.318 0.00225 0.2 0.4505 0.9412 2078228 Maybridge3_005645 C/C(=N\Cc1cccnc1)/c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A14 compound treatment 0.32 0.0144 1.16 0.327 0.0113 1.02 1.5406 0.998 2078229 Maybridge3_005646 Oc1ccc(Cl)cc1/C=N/Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A15 compound treatment 0.319 0.0134 1.08 0.322 0.00625 0.57 1.1627 0.9552 2078230 Maybridge3_005647 CSc1cccc(NC(=O)CC2S/C(=N/c3cccc(SC)c3)/NC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A16 compound treatment 0.377 0.0714 5.75 0.381 0.0653 5.92 8.2522 0.9999 2078231 Maybridge3_005648 NC(=O)C1=C(NC(C(=N1)c2ccccc2)c3ccccc3)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A17 compound treatment 0.338 0.0324 2.61 0.342 0.0263 2.38 3.5283 0.999 2078232 Maybridge3_005649 Oc1ccc(Br)cc1/C=N/Cc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A18 compound treatment 0.301 -0.00462 -0.37 0.309 -0.00675 -0.61 -0.6966 -0.9715 1214261 Maybridge3_005650 Clc1ccc(NC(=O)Oc2ccccc2N3CCSCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A19 compound treatment 0.306 3.75E-4 0.03 0.311 -0.00475 -0.43 -0.2835 -0.656 2078233 Maybridge3_005651 Clc1cc(Cl)cc(Nc2n[nH]c(=S)s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A20 compound treatment 0.07 -0.236 -18.97 0.074 -0.242 -21.94 -28.9334 -0.9974 2078234 Maybridge3_005652 Clc1ccc(Oc2ccccc2N3C(=O)C=CC3=O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A21 compound treatment 0.31 0.00438 0.35 0.317 0.00125 0.11 0.3293 0.8898 1921450 Maybridge3_005653 OCCSc1nc2ccccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A22 compound treatment 0.31 0.00438 0.35 0.316 2.5E-4 0.02 0.2652 0.7511 2078235 Maybridge3_005654 O=C(CC(CC(=O)c1ccccc1)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A23 mock treatment 0.293 -0.0126 -1.02 0.308 -0.00775 -0.7 -1.2163 -0.9838 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 A24 positive control 0.081 -0.225 -18.09 0.088 -0.228 -20.67 -27.4085 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B01 compound treatment 0.348 0.0424 3.41 0.356 0.0403 3.65 4.9963 0.9994 1616152 Maybridge3_005655 Brc1ccccc1C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B02 compound treatment 0.327 0.0214 1.72 0.338 0.0222 2.02 2.6452 0.9968 1211437 Maybridge3_005656 O=C1COCC(=O)N1Cc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B03 compound treatment 0.322 0.0164 1.32 0.334 0.0182 1.66 2.1038 0.9936 2078236 Maybridge3_005657 Oc1c(Br)cc(Br)cc1C(=O)NCC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B04 compound treatment 0.32 0.0144 1.16 0.326 0.0103 0.93 1.4764 0.9941 1229010 Maybridge3_005658 Cc1ccc(nc1)n2cc3ccccc3c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B05 compound treatment 0.319 0.0134 1.08 0.329 0.0133 1.2 1.612 0.9985 2078237 Maybridge3_005659 CC(=O)SC1CC(=O)N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B06 compound treatment 0.326 0.0204 1.64 0.33 0.0143 1.29 2.0748 0.9931 1500011 Maybridge3_005660 O=C1C(=C(NCCC2=CCCCC2)C#N)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B07 compound treatment 0.321 0.0154 1.24 0.332 0.0163 1.48 1.9185 0.9962 1131936 Maybridge3_005661 OC(=O)CSCC(=O)Nc1ccc2OCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B08 compound treatment 0.319 0.0134 1.08 0.329 0.0133 1.2 1.612 0.9985 2078238 Maybridge3_005662 N#CCC1(CCc2ccccc21)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B09 compound treatment 0.317 0.0114 0.92 0.328 0.0123 1.11 1.434 0.9954 2078239 Maybridge3_005663 CSc1nnc(Nc2ccc(Cl)cc2Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B10 compound treatment 0.326 0.0204 1.64 0.332 0.0163 1.48 2.2032 0.9986 1071586 Maybridge3_005664 COc1ccc(NC2=CC(=O)N(C2=O)c3ccc(OC)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B11 compound treatment 0.319 0.0134 1.08 0.328 0.0123 1.11 1.5479 0.9999 1605725 Maybridge3_005665 CC1SC(N(C1=O)c2ccc(Cl)cc2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B12 compound treatment 0.067 -0.239 -19.22 0.07 -0.246 -22.31 -29.361 -0.9972 2078240 Maybridge3_005666 CC(C)(C)c1ccccc1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B13 compound treatment 0.314 0.00838 0.67 0.32 0.00425 0.39 0.7497 0.9649 1339068 Maybridge3_005667 Cc1ccc(c(O)c1C)C2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B14 compound treatment 0.315 0.00938 0.75 0.324 0.00825 0.75 1.0633 1.0 1172604 Maybridge3_005668 O=C1COCC(=O)N1c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B15 compound treatment 0.322 0.0164 1.32 0.335 0.0193 1.75 2.168 0.9904 2078241 Maybridge3_005669 Fc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B16 compound treatment 0.32 0.0144 1.16 0.33 0.0143 1.29 1.7332 0.9985 2078242 Maybridge3_005670 CCOC(=O)C(N)CSC1CC(=O)N(C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B17 compound treatment 0.323 0.0174 1.4 0.33 0.0143 1.29 1.904 0.9992 2078243 Maybridge3_005671 COc1ccc(Cl)cc1NC(=C2C(=O)c3ccccc3C2=O)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B18 compound treatment 0.328 0.0224 1.8 0.347 0.0313 2.84 3.2798 0.976 2078244 Maybridge3_005672 CC(C)(C)c1ccc(cc1)c2nnc(N)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B19 compound treatment 0.346 0.0404 3.25 0.354 0.0382 3.47 4.7541 0.9995 2078245 Maybridge3_005673 COc1ccc(/C=N/CCc2cccs2)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B20 compound treatment 0.312 0.00638 0.51 0.326 0.0103 0.93 1.0209 0.9607 1677349 Maybridge3_005674 Cc1ccc(CNc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B21 compound treatment 0.325 0.0194 1.56 0.333 0.0173 1.57 2.2104 1.0 1690607 Maybridge3_005675 OC(=O)CCSC1CC(=O)N(C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B22 compound treatment 0.32 0.0144 1.16 0.329 0.0133 1.2 1.669 0.9998 2078246 Maybridge3_005676 Cc1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B23 mock treatment 0.303 -0.00262 -0.21 0.321 0.00525 0.48 0.1875 0.3597 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 B24 positive control 0.084 -0.222 -17.85 0.087 -0.229 -20.76 -27.3018 -0.9972 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C01 compound treatment 0.315 0.00938 0.75 0.326 0.0103 0.93 1.1917 0.9946 2078247 Maybridge3_005677 Fc1ccc(Cn2nnc(n2)c3cccc(c3)C(F)(F)F)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C02 compound treatment 0.333 0.0274 2.2 0.346 0.0302 2.75 3.5004 0.9941 2078248 Maybridge3_005678 Oc1ccccc1/C=N/c2sc3CCCc3c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C03 compound treatment 0.303 -0.00262 -0.21 0.313 -0.00275 -0.25 -0.326 -0.9966 2078249 Maybridge3_005679 Cc1ccc(CNc2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C04 compound treatment 0.326 0.0204 1.64 0.327 0.0113 1.02 1.8823 0.974 2078250 Maybridge3_005680 CC(/N=C/c1cc(Cl)ccc1O)c2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C05 compound treatment 0.331 0.0254 2.04 0.339 0.0233 2.11 2.9372 0.9999 1741192 Maybridge3_005681 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C06 compound treatment 0.327 0.0214 1.72 0.336 0.0203 1.84 2.5169 0.9995 2078251 Maybridge3_005682 CCn1c2ccccc2c3cc(NC(=O)/C=C/C(=O)O)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C07 compound treatment 0.313 0.00738 0.59 0.323 0.00725 0.66 0.8853 0.9987 1021361 Maybridge3_005683 OC(=O)CC(NC(=O)c1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C08 compound treatment 0.312 0.00638 0.51 0.328 0.0123 1.11 1.1493 0.9384 1124743 Maybridge3_005684 CC(C)(C)c1ccc(cc1)c2nc3ccccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C09 compound treatment 0.302 -0.00362 -0.29 0.317 0.00125 0.11 -0.1262 -0.4029 1090054 Maybridge3_005685 COc1ccccc1Nc2n[nH]c(=S)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C10 compound treatment 0.32 0.0144 1.16 0.33 0.0143 1.29 1.7332 0.9985 1442578 Maybridge3_005686 Clc1ccc(CN2C(SCC2=O)c3cccnc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C11 compound treatment 0.306 3.75E-4 0.03 0.318 0.00225 0.2 0.1658 0.8029 2078252 Maybridge3_005687 Cc1cc(NC(=O)/C=C/C(=O)O)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C12 compound treatment 0.355 0.0494 3.98 0.355 0.0393 3.56 5.3307 0.9985 2078253 Maybridge3_005688 O=C1C(=C(Nc2ccc3OCCOc3c2)C#N)C(=O)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C13 compound treatment 0.313 0.00738 0.59 0.318 0.00225 0.2 0.5644 0.8986 2078254 Maybridge3_005689 CCc1ccc(Nc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C14 compound treatment 0.316 0.0104 0.84 0.334 0.0182 1.66 1.7621 0.9498 2078255 Maybridge3_005690 OC(=O)/C=C/C(=O)Nc1nccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C15 compound treatment 0.314 0.00838 0.67 0.322 0.00625 0.57 0.878 0.9963 2078256 Maybridge3_005691 CSc1cccc(NC(=O)CC2S/C(=N/c3ccc(F)c(F)c3)/NC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C16 compound treatment 0.242 -0.0636 -5.12 0.251 -0.0648 -5.88 -7.7788 -0.9977 2078257 Maybridge3_005692 Clc1cccc(c1)N2CSC(=C(C#N)C#N)SC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C17 compound treatment 0.398 0.0924 7.44 0.401 0.0853 7.74 10.7317 0.9998 1915666 Maybridge3_005693 Oc1ccc2ccccc2c1/C=N/Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C18 compound treatment 0.313 0.00738 0.59 0.335 0.0193 1.75 1.6555 0.897 2078258 Maybridge3_005694 OC(=O)/C=C/C(=O)Nc1ccc(cc1)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C19 compound treatment 0.323 0.0174 1.4 0.326 0.0103 0.93 1.6472 0.9804 2078259 Maybridge3_005695 Oc1ccccc1/C=N/c2ccc(cc2)S(=O)(=O)\N=C\c3ccccc3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C20 compound treatment 0.33 0.0244 1.96 0.339 0.0233 2.11 2.8802 0.9993 2078260 Maybridge3_005696 Clc1cccc(c1)N2C(=O)C=C(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C21 compound treatment 0.364 0.0584 4.7 0.377 0.0612 5.56 7.2553 0.9965 2078261 Maybridge3_005697 CCO/C=C\1/SC(=S)N(C1=O)c2cc(OC)cc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C22 compound treatment 0.329 0.0234 1.88 0.338 0.0222 2.02 2.7591 0.9994 1677967 Maybridge3_005698 COc1ccc(Cc2nnc(Nc3ccc(C)cc3)o2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C23 mock treatment 0.297 -0.00862 -0.69 0.306 -0.00975 -0.89 -1.1169 -0.9928 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 C24 positive control 0.084 -0.222 -17.85 0.088 -0.228 -20.67 -27.2377 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D01 compound treatment 0.33 0.0244 1.96 0.339 0.0233 2.11 2.8802 0.9993 2078262 Maybridge3_005699 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D02 compound treatment 0.324 0.0184 1.48 0.335 0.0193 1.75 2.2819 0.9966 1381937 Maybridge3_005700 OC(=O)c1ccccc1C(=O)NCc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D03 compound treatment 0.322 0.0164 1.32 0.332 0.0163 1.48 1.9754 0.9984 1183202 Maybridge3_005701 O=C1CS(=O)(=O)C(N1c2ccccc2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D04 compound treatment 0.311 0.00538 0.43 0.324 0.00825 0.75 0.8356 0.966 2078263 Maybridge3_005702 CCOC(=S)Nc1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D05 compound treatment 0.327 0.0214 1.72 0.338 0.0222 2.02 2.6452 0.9968 1701711 Maybridge3_005703 OC(=O)CCCC(=O)Nc1ccc(F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D06 compound treatment 0.322 0.0164 1.32 0.339 0.0233 2.11 2.4247 0.9744 1461971 Maybridge3_005704 O=c1cc(NCCC2=CCCCC2)c3ccccc3o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D07 compound treatment 0.325 0.0194 1.56 0.334 0.0182 1.66 2.2746 0.9996 1127442 Maybridge3_005705 O=C1CSCC(=O)N1c2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D08 compound treatment 0.322 0.0164 1.32 0.337 0.0213 1.93 2.2963 0.9828 1217015 Maybridge3_005706 COc1ccc2c(CCCC2(CC#N)C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D09 compound treatment 0.32 0.0144 1.16 0.331 0.0153 1.38 1.7973 0.996 1117856 Maybridge3_005707 CSc1nnc(NCc2cccc(Cl)c2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D10 compound treatment 0.212 -0.0936 -7.54 0.25 -0.0658 -5.97 -9.5513 -0.9933 1155297 Maybridge3_005708 Clc1cc(Cl)cc(c1)N2C(=O)CC(C2=O)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D11 compound treatment 0.322 0.0164 1.32 0.335 0.0193 1.75 2.168 0.9904 1408183 Maybridge3_005709 CC1SC(N(C1=O)c2ccc(F)cc2F)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D12 compound treatment 0.323 0.0174 1.4 0.333 0.0173 1.57 2.0965 0.9984 2078264 Maybridge3_005710 OC(=O)/C=C/C(=O)NCc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D13 compound treatment 0.334 0.0284 2.28 0.35 0.0343 3.11 3.814 0.9885 1486931 Maybridge3_005711 COc1ccc(O)c(c1)C(=O)C2N(C(=O)c3ccccc23)c4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D14 compound treatment 0.32 0.0144 1.16 0.334 0.0182 1.66 1.9899 0.9846 1657982 Maybridge3_005712 O=C1CCC(=O)N1c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D15 compound treatment 0.321 0.0154 1.24 0.334 0.0182 1.66 2.0468 0.9897 2078265 Maybridge3_005713 Fc1cccc(F)c1c2nc3ccc(SC#N)cc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D16 compound treatment 0.32 0.0144 1.16 0.332 0.0163 1.48 1.8615 0.9928 1723958 Maybridge3_005714 CCOC(=O)C1CSC(CC(=O)Nc2ccccc2)C(=O)N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D17 compound treatment 0.326 0.0204 1.64 0.337 0.0213 1.93 2.5241 0.9968 1700520 Maybridge3_005715 COc1ccc(Cl)cc1NC(=O)CSCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D18 compound treatment 0.32 0.0144 1.16 0.335 0.0193 1.75 2.0541 0.98 2078266 Maybridge3_005716 CC(O)c1nc2cc(Cl)ccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D19 compound treatment 0.311 0.00538 0.43 0.324 0.00825 0.75 0.8356 0.966 2078267 Maybridge3_005717 FC(F)(F)c1ccc(NC(C#N)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D20 compound treatment 0.314 0.00838 0.67 0.326 0.0103 0.93 1.1348 0.9875 1161511 Maybridge3_005718 COc1ccc(CNc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D21 compound treatment 0.324 0.0184 1.48 0.337 0.0213 1.93 2.4102 0.9914 2078268 Maybridge3_005719 OC(=O)/C=C/C(=O)Nc1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D22 compound treatment 0.324 0.0184 1.48 0.332 0.0163 1.48 2.0893 1.0 2078269 Maybridge3_005720 Cc1ccc(cc1F)N2C(=O)CC(CC=C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D23 mock treatment 0.303 -0.00262 -0.21 0.317 0.00125 0.11 -0.0692 -0.2886 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 D24 positive control 0.086 -0.22 -17.69 0.09 -0.226 -20.49 -26.9954 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E01 compound treatment 0.326 0.0204 1.64 0.335 0.0193 1.75 2.3957 0.9995 2078270 Maybridge3_005721 Cc1cccc(Cl)c1c2nn[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E02 compound treatment 0.323 0.0174 1.4 0.336 0.0203 1.84 2.2891 0.9909 2078271 Maybridge3_005722 OC(=O)/C=C/C(=O)Nc1ccc2OCCOc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E03 compound treatment 0.315 0.00938 0.75 0.329 0.0133 1.2 1.3843 0.9748 2078272 Maybridge3_005723 Cc1ccc(CNc2cccnc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E04 compound treatment 0.316 0.0104 0.84 0.328 0.0123 1.11 1.377 0.9901 2078273 Maybridge3_005724 C=CC/N=C/1\NC(=O)C(CC(=O)Nc2ccccc2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E05 compound treatment 0.368 0.0624 5.02 0.374 0.0583 5.29 7.2905 0.9997 2078274 Maybridge3_005725 CCO/C=C/1\SC(=S)N(CCc2ccc(OC)c(OC)c2)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E06 compound treatment 0.073 -0.233 -18.73 0.076 -0.24 -21.76 -28.6342 -0.9972 2078275 Maybridge3_005726 CCn1c2ccccc2c3cc(ccc13)N4C(=O)C=CC4=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E07 compound treatment 0.302 -0.00362 -0.29 0.318 0.00225 0.2 -0.062 -0.174 2078276 Maybridge3_005727 Cc1c(C)c(C)c(CSC(=N)N)c(C)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E08 compound treatment 0.322 0.0164 1.32 0.335 0.0193 1.75 2.168 0.9904 1660547 Maybridge3_005728 CC(C)(C)c1ccc(cc1)C(=C(C#N)C#N)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E09 compound treatment 0.322 0.0164 1.32 0.334 0.0182 1.66 2.1038 0.9936 2078277 Maybridge3_005729 O=C1CSC(=S)N1CCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E10 compound treatment 0.322 0.0164 1.32 0.335 0.0193 1.75 2.168 0.9904 2078278 Maybridge3_005730 Clc1ccc(CSc2nnc(s2)c3ccncc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E11 compound treatment 0.322 0.0164 1.32 0.333 0.0173 1.57 2.0396 0.9963 2078279 Maybridge3_005731 Clc1ccc(Oc2ccc(cc2)N3C(=O)CSC3=S)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E12 compound treatment 0.342 0.0364 2.93 0.327 0.0113 1.02 2.7933 0.9005 1184213 Maybridge3_005732 OC(=O)CC(NC(=O)Cc1cccc2ccccc12)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E13 compound treatment 0.073 -0.233 -18.73 0.077 -0.239 -21.67 -28.57 -0.9974 2078280 Maybridge3_005733 CSc1ccc(cc1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E14 compound treatment 0.314 0.00838 0.67 0.332 0.0163 1.48 1.5199 0.9371 1701575 Maybridge3_005734 CC(C)CCSc1nnc(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E15 compound treatment 0.312 0.00638 0.51 0.328 0.0123 1.11 1.1493 0.9384 2078281 Maybridge3_005735 Clc1ccc(Cl)c(Nc2nn(c3ccccc3)c(=S)s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E16 compound treatment 0.322 0.0164 1.32 0.334 0.0182 1.66 2.1038 0.9936 1467444 Maybridge3_005736 OC(=O)CC(CC(=O)Oc1ccc(F)cc1)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E17 compound treatment 0.323 0.0174 1.4 0.337 0.0213 1.93 2.3533 0.9876 2078282 Maybridge3_005737 Oc1ccc(Br)cc1/C=N/Cc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E18 compound treatment 0.105 -0.201 -16.16 0.112 -0.204 -18.49 -24.5015 -0.9977 2078283 Maybridge3_005738 O=C1C=CC(=O)N1c2ccc(cc2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E19 compound treatment 0.304 -0.00162 -0.13 0.317 0.00125 0.11 -0.0123 -0.071 2078284 Maybridge3_005739 Cc1ccc(C)c(Nc2n[nH]c(=S)s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E20 compound treatment 0.34 0.0344 2.77 0.349 0.0333 3.02 4.0915 0.9991 2078285 Maybridge3_005740 Cc1ccsc1/C=C\2/N=C(OC2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E21 compound treatment 0.326 0.0204 1.64 0.338 0.0222 2.02 2.5883 0.9947 2078286 Maybridge3_005741 Cc1onc(c1c2n[nH]c(N)c2C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E22 compound treatment 0.329 0.0234 1.88 0.336 0.0203 1.84 2.6307 0.9999 1691043 Maybridge3_005742 Fc1ccccc1C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E23 mock treatment 0.301 -0.00462 -0.37 0.313 -0.00275 -0.25 -0.4399 -0.9811 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 E24 positive control 0.088 -0.218 -17.52 0.091 -0.225 -20.4 -26.8173 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F01 compound treatment 0.326 0.0204 1.64 0.334 0.0182 1.66 2.3315 1.0 2078287 Maybridge3_005743 Cc1cc(NC(=O)C2C(C3CC2C=C3)C(=O)O)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F02 compound treatment 0.33 0.0244 1.96 0.334 0.0182 1.66 2.5593 0.9964 2078288 Maybridge3_005744 FC(F)(F)Oc1ccc(Nc2cc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F03 compound treatment 0.322 0.0164 1.32 0.334 0.0182 1.66 2.1038 0.9936 1667940 Maybridge3_005745 CC(CC(=O)O)CC(=O)Nc1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F04 compound treatment 0.324 0.0184 1.48 0.333 0.0173 1.57 2.1535 0.9996 1235146 Maybridge3_005746 OC1(NC(=O)Cc2ccccc2)C(=O)c3ccccc3C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F05 compound treatment 0.324 0.0184 1.48 0.333 0.0173 1.57 2.1535 0.9996 2078289 Maybridge3_005747 OC(=O)CCCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F06 compound treatment 0.323 0.0174 1.4 0.335 0.0193 1.75 2.2249 0.9939 2078290 Maybridge3_005748 FC(F)(F)Oc1ccc(Nc2nc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F07 compound treatment 0.324 0.0184 1.48 0.337 0.0213 1.93 2.4102 0.9914 1159841 Maybridge3_005749 O=C1CSC(N1CC2CC2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F08 compound treatment 0.316 0.0104 0.84 0.347 0.0313 2.84 2.5965 0.8781 2078291 Maybridge3_005750 OC(=O)CCC(=O)Nc1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F09 compound treatment 0.315 0.00938 0.75 0.334 0.0182 1.66 1.7052 0.9367 2078292 Maybridge3_005751 CSc1cc(n[nH]1)c2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F10 compound treatment 0.068 -0.238 -19.14 0.073 -0.243 -22.03 -29.1115 -0.9975 1034515 Maybridge3_005752 Cc1cc(C)cc(c1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F11 compound treatment 0.323 0.0174 1.4 0.341 0.0253 2.29 2.61 0.972 2078293 Maybridge3_005753 CC1SC(N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F12 compound treatment 0.325 0.0194 1.56 0.341 0.0253 2.29 2.7239 0.9824 1501573 Maybridge3_005754 Fc1ccc(CNC(=O)Cc2cc3ccccc3o2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F13 compound treatment 0.339 0.0334 2.69 0.355 0.0393 3.56 4.4197 0.9903 1271816 Maybridge3_005755 COc1ccccc1c2oc3ccccc3c(=O)c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F14 compound treatment 0.322 0.0164 1.32 0.341 0.0253 2.29 2.5531 0.9655 1383539 Maybridge3_005756 O=C1COCC(=O)N1CCc2c[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F15 compound treatment 0.325 0.0194 1.56 0.342 0.0263 2.38 2.7881 0.9789 1590035 Maybridge3_005757 O=C(Oc1cccc2C(=O)CCc21)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F16 compound treatment 0.352 0.0464 3.73 0.352 0.0362 3.29 4.9673 0.998 2078294 Maybridge3_005758 CC(=O)Oc1nc(c2ccc(cc2)C(C)(C)C)n(n1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F17 compound treatment 0.33 0.0244 1.96 0.337 0.0213 1.93 2.7519 1.0 1383926 Maybridge3_005759 COc1ccc(Cl)cc1NC(=O)CC(C)(C)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F18 compound treatment 0.331 0.0254 2.04 0.346 0.0302 2.75 3.3865 0.9894 1184032 Maybridge3_005760 CC1OCN(Cn2c1nc3ccccc23)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F19 compound treatment 0.313 0.00738 0.59 0.324 0.00825 0.75 0.9495 0.9934 1655485 Maybridge3_005761 Ic1ccc(NC(C#N)c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F20 compound treatment 0.319 0.0134 1.08 0.341 0.0253 2.29 2.3823 0.9407 2078295 Maybridge3_005762 N=C1NC(=O)C(CC(=O)Nc2cccc3ccccc23)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F21 compound treatment 0.33 0.0244 1.96 0.34 0.0243 2.2 2.9444 0.9984 2078296 Maybridge3_005763 OC(=O)/C=C/C(=O)Nc1ccccc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F22 compound treatment 0.327 0.0214 1.72 0.339 0.0233 2.11 2.7094 0.9949 1257187 Maybridge3_005764 CC(C)(C)c1ccc(cc1)N2C(=O)CC(CC=C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F23 mock treatment 0.299 -0.00662 -0.53 0.314 -0.00175 -0.16 -0.4896 -0.8795 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 F24 positive control 0.088 -0.218 -17.52 0.091 -0.225 -20.4 -26.8173 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G01 compound treatment 0.318 0.0124 1.0 0.329 0.0133 1.2 1.5551 0.9956 1317800 Maybridge3_005765 Clc1ccc(cc1)c2nnc(o2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G02 compound treatment 0.072 -0.234 -18.81 0.077 -0.239 -21.67 -28.627 -0.9975 2078297 Maybridge3_005766 O=C1C=CC(=O)N1c2ccc3OCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G03 compound treatment 0.313 0.00738 0.59 0.33 0.0143 1.29 1.3346 0.9377 1058235 Maybridge3_005767 COc1ccc(CNc2ccccc2C(=O)O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G04 compound treatment 0.31 0.00438 0.35 0.325 0.00925 0.84 0.8428 0.9256 2078298 Maybridge3_005768 COc1ccc(CSC(=N)Nc2ccccc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G05 compound treatment 0.398 0.0924 7.44 0.411 0.0953 8.65 11.3735 0.9972 2078299 Maybridge3_005769 CCO/C=C/1\SC(=S)N(Cc2ccccc2)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G06 compound treatment 0.314 0.00838 0.67 0.322 0.00625 0.57 0.878 0.9963 1524297 Maybridge3_005770 CC(NCc1ccccc1)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G07 compound treatment 0.31 0.00438 0.35 0.333 0.0173 1.57 1.3563 0.8451 2078300 Maybridge3_005771 CCOc1ccccc1/N=C\2/NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G08 compound treatment 0.312 0.00638 0.51 0.332 0.0163 1.48 1.406 0.9002 1476079 Maybridge3_005772 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G09 compound treatment 0.397 0.0914 7.36 0.406 0.0903 8.19 10.9957 0.9986 2078301 Maybridge3_005773 CO/C=C/1\SC(=S)N(CCc2ccccc2)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G10 compound treatment 0.308 0.00238 0.19 0.329 0.0133 1.2 0.9857 0.8094 2078302 Maybridge3_005774 CCOC(=O)c1cccc(CSC(=N)N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G11 compound treatment 0.308 0.00238 0.19 0.33 0.0143 1.29 1.0499 0.8029 2078303 Maybridge3_005775 O=C(CC(C#N)c1ccccc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G12 compound treatment 0.319 0.0134 1.08 0.34 0.0243 2.2 2.3181 0.9459 1728358 Maybridge3_005776 O=C1CSC(N1Cc2ccc3OCOc3c2)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G13 compound treatment 0.317 0.0114 0.92 0.333 0.0173 1.57 1.7549 0.9674 2078304 Maybridge3_005777 COC(=O)c1ccccc1NC2=NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G14 compound treatment 0.317 0.0114 0.92 0.334 0.0182 1.66 1.8191 0.961 2078305 Maybridge3_005778 CC1(NC(=O)CS1)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G15 compound treatment 0.079 -0.227 -18.25 0.085 -0.231 -20.95 -27.7149 -0.9976 2078306 Maybridge3_005779 O=C1C=CC(=O)N1c2ccc3scnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G16 compound treatment 0.314 0.00838 0.67 0.332 0.0163 1.48 1.5199 0.9371 1151798 Maybridge3_005780 COc1cc(cc(OC)c1OC)C(CC#N)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G17 compound treatment 0.298 -0.00762 -0.61 0.314 -0.00175 -0.16 -0.5465 -0.8617 2078307 Maybridge3_005781 Clc1cc(Br)ccc1Nc2n[nH]c(=S)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G18 compound treatment 0.075 -0.231 -18.57 0.077 -0.239 -21.67 -28.4562 -0.997 2078308 Maybridge3_005782 CCC(C)c1ccc(cc1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G19 compound treatment 0.313 0.00738 0.59 0.328 0.0123 1.11 1.2062 0.9568 2078309 Maybridge3_005783 Cc1ccc(C)c(/N=C/c2ccccc2O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G20 compound treatment 0.311 0.00538 0.43 0.327 0.0113 1.02 1.0281 0.927 1713859 Maybridge3_005784 Clc1ccc(CCNc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G21 compound treatment 0.319 0.0134 1.08 0.327 0.0113 1.02 1.4837 0.9996 2078310 Maybridge3_005785 CC(C)c1ccccc1NC2=NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G22 compound treatment 0.341 0.0354 2.85 0.349 0.0333 3.02 4.1484 0.9996 2078311 Maybridge3_005786 Cc1ccc(/C=N/C(=C(\N)/C#N)/C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G23 mock treatment 0.305 -6.25E-4 -0.05 0.315 -7.5E-4 -0.07 -0.0837 -0.989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 G24 positive control 0.088 -0.218 -17.52 0.094 -0.222 -20.13 -26.6248 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H01 compound treatment 0.324 0.0184 1.48 0.335 0.0193 1.75 2.2819 0.9966 2078312 Maybridge3_005787 OC(=O)/C=C/C(=O)NCC1CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H02 compound treatment 0.337 0.0314 2.53 0.358 0.0423 3.84 4.4983 0.9795 2078313 Maybridge3_005788 Cc1ccc(N/C=C/2\C(=O)N(C(c3cccnc3)S2(=O)=O)c4ccc(F)cc4F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H03 compound treatment 0.314 0.00838 0.67 0.305 -0.0107 -0.98 -0.2131 -0.1797 1397380 Maybridge3_005789 CC(CC(=O)O)CC(=O)Nc1cc(C)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H04 compound treatment 0.324 0.0184 1.48 0.337 0.0213 1.93 2.4102 0.9914 1474311 Maybridge3_005790 CC1(C)COC(=N1)c2ccccc2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H05 compound treatment 0.325 0.0194 1.56 0.341 0.0253 2.29 2.7239 0.9824 1715379 Maybridge3_005791 CC(=O)SC1CC(=O)N(C1=O)c2c(C)cccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H06 compound treatment 0.315 0.00938 0.75 0.339 0.0233 2.11 2.0261 0.904 1365999 Maybridge3_005792 CCOC(=O)C(C)c1ccc2cc(OC)ccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H07 compound treatment 0.322 0.0164 1.32 0.336 0.0203 1.84 2.2322 0.9867 1273308 Maybridge3_005793 CCC(C)(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H08 compound treatment 0.321 0.0154 1.24 0.333 0.0173 1.57 1.9827 0.9932 2078314 Maybridge3_005794 FC(F)(F)Oc1ccc(cc1)N2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H09 compound treatment 0.307 0.00138 0.11 0.336 0.0203 1.84 1.378 0.7483 2078315 Maybridge3_005795 CCOC(=O)Sc1ccc2ccccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H10 compound treatment 0.288 -0.0176 -1.42 0.32 0.00425 0.39 -0.7308 -0.4969 2078316 Maybridge3_005796 Oc1ccccc1/C=N/Cc2csc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H11 compound treatment 0.325 0.0194 1.56 0.338 0.0222 2.02 2.5313 0.9919 1172116 Maybridge3_005797 COc1ccc(CN2C(SC(C)C2=O)c3cccnc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H12 compound treatment 0.316 0.0104 0.84 0.325 0.00925 0.84 1.1845 1.0 2078317 Maybridge3_005798 Cc1ccc2oc(nc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H13 compound treatment 0.325 0.0194 1.56 0.34 0.0243 2.2 2.6597 0.9858 2078318 Maybridge3_005799 COc1ccc(CC(=O)NCc2cccc(Cl)c2)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H14 compound treatment 0.323 0.0174 1.4 0.34 0.0243 2.2 2.5458 0.9761 2078319 Maybridge3_005800 COc1ccc(CNC(=O)/C=C/C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H15 compound treatment 0.322 0.0164 1.32 0.324 0.00825 0.75 1.4619 0.9641 2078320 Maybridge3_005801 FC(F)(F)c1ccc(cc1)N2C(c3ccccn3)S(=O)(=O)CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H16 compound treatment 0.321 0.0154 1.24 0.336 0.0203 1.84 2.1752 0.9815 2078321 Maybridge3_005802 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H17 compound treatment 0.32 0.0144 1.16 0.334 0.0182 1.66 1.9899 0.9846 2078322 Maybridge3_005803 COc1ccc(Cl)cc1NC(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H18 compound treatment 0.332 0.0264 2.12 0.353 0.0372 3.38 3.8927 0.9749 1357039 Maybridge3_005804 COc1ccc(cc1)N2COC(C)c3nc4ccccc4n3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H19 compound treatment 0.314 0.00838 0.67 0.326 0.0103 0.93 1.1348 0.9875 1162213 Maybridge3_005805 CSc1cccc(NC(C#N)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H20 compound treatment 0.319 0.0134 1.08 0.342 0.0263 2.38 2.4464 0.9356 2078323 Maybridge3_005806 CSc1nnc(/N=C/c2ccccc2O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H21 compound treatment 0.111 -0.195 -15.67 0.118 -0.198 -17.95 -23.7747 -0.9977 2078324 Maybridge3_005807 FC(F)(F)Oc1ccccc1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H22 compound treatment 0.323 0.0174 1.4 0.335 0.0193 1.75 2.2249 0.9939 2078325 Maybridge3_005808 FC(F)(F)c1ccc(cc1)N2C(=O)CC(CC=C)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H23 mock treatment 0.308 0.00238 0.19 0.321 0.00525 0.48 0.4722 0.9196 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 H24 positive control 0.089 -0.217 -17.44 0.095 -0.221 -20.04 -26.5037 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I01 compound treatment 0.405 0.0994 8.0 0.41 0.0943 8.56 11.7079 0.9994 2078326 Maybridge3_005809 Ic1ccc(Nc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I02 compound treatment 0.334 0.0284 2.28 0.348 0.0323 2.93 3.6857 0.9925 1585685 Maybridge3_005810 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I03 compound treatment 0.328 0.0224 1.8 0.342 0.0263 2.38 2.9589 0.9905 2078327 Maybridge3_005811 COc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I04 compound treatment 0.309 0.00338 0.27 0.324 0.00825 0.75 0.7217 0.9059 2078328 Maybridge3_005812 CCN(CC)C(=S)Oc1ccc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I05 compound treatment 0.339 0.0334 2.69 0.358 0.0423 3.84 4.6122 0.9849 1004834 Maybridge3_005813 COc1ccc(cc1)N2C(=O)CSC2=S 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I06 compound treatment 0.314 0.00838 0.67 0.335 0.0193 1.75 1.7124 0.9143 2078329 Maybridge3_005814 Cc1onc(c1C(=O)N2C=Cc3ccccc3C2C#N)c4ccccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I07 compound treatment 0.319 0.0134 1.08 0.343 0.0273 2.47 2.5106 0.9306 1546147 Maybridge3_005815 Cc1ccccc1c2nc3cc(Cl)ccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I08 compound treatment 0.319 0.0134 1.08 0.34 0.0243 2.2 2.3181 0.9459 1685517 Maybridge3_005816 COc1ccc(Br)c(c1)c2nc3ccccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I09 compound treatment 0.317 0.0114 0.92 0.331 0.0153 1.38 1.6265 0.9799 2078330 Maybridge3_005817 Cc1onc(c1c2nnnn2c3ccccc3)c4ccccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I10 compound treatment 0.33 0.0244 1.96 0.347 0.0313 2.84 3.3937 0.9838 1071312 Maybridge3_005818 COc1ccc(Nc2cccc(Cl)c2)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I11 compound treatment 0.325 0.0194 1.56 0.341 0.0253 2.29 2.7239 0.9824 1181592 Maybridge3_005819 CCOC(=O)c1ccc(cc1)N2C(=O)CC(Sc3ccc(C)cc3)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I12 compound treatment 0.318 0.0124 1.0 0.333 0.0173 1.57 1.8118 0.9762 2078331 Maybridge3_005820 OC(=O)/C=C/C(=O)NCc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I13 compound treatment 0.323 0.0174 1.4 0.337 0.0213 1.93 2.3533 0.9876 2078332 Maybridge3_005821 COC(=O)c1ccccc1NC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I14 compound treatment 0.323 0.0174 1.4 0.338 0.0222 2.02 2.4175 0.9839 1522974 Maybridge3_005822 OC(=O)CC(CC(=O)O)c1ccc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I15 compound treatment 0.077 -0.229 -18.41 0.084 -0.232 -21.04 -27.893 -0.9978 2078333 Maybridge3_005823 O=C(c1ccccc1)c2ccccc2N3C(=O)C=CC3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I16 compound treatment 0.321 0.0154 1.24 0.339 0.0233 2.11 2.3678 0.9677 1455388 Maybridge3_005824 Cc1ccc2nc(oc(=O)c2c1)c3cc4ccccc4o3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I17 compound treatment 0.329 0.0234 1.88 0.341 0.0253 2.29 2.9517 0.9952 1113873 Maybridge3_005825 Clc1ccc(cc1)C2OC(=O)c3ccccc3S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I18 compound treatment 0.111 -0.195 -15.67 0.126 -0.19 -17.22 -23.2612 -0.9989 2078334 Maybridge3_005826 O=C1C=CC(=O)N1c2cccc(C#N)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I19 compound treatment 0.348 0.0424 3.41 0.356 0.0403 3.65 4.9963 0.9994 2078335 Maybridge3_005827 Cc1cccc(Cl)c1N/2C(=O)C(CC(=O)O)S\C2=N/C3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I20 compound treatment 0.325 0.0194 1.56 0.339 0.0233 2.11 2.5955 0.989 2078336 Maybridge3_005828 Fc1ccc(NC(=O)c2ccccc2I)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I21 compound treatment 0.105 -0.201 -16.16 0.111 -0.205 -18.59 -24.5656 -0.9976 2078337 Maybridge3_005829 FC(F)(F)c1ccc(cc1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I22 compound treatment 0.332 0.0264 2.12 0.338 0.0222 2.02 2.9299 0.9997 1722086 Maybridge3_005830 O=C(CC1OC(=O)c2ccccc12)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I23 mock treatment 0.307 0.00138 0.11 0.319 0.00325 0.3 0.2869 0.9105 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 I24 positive control 0.09 -0.216 -17.36 0.094 -0.222 -20.13 -26.5109 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J01 compound treatment 0.322 0.0164 1.32 0.333 0.0173 1.57 2.0396 0.9963 1201263 Maybridge3_005831 O=C1CSCC(=O)N1c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J02 compound treatment 0.327 0.0214 1.72 0.336 0.0203 1.84 2.5169 0.9995 1416459 Maybridge3_005832 Fc1ccc(Nc2cc(=O)oc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J03 compound treatment 0.319 0.0134 1.08 0.326 0.0103 0.93 1.4195 0.9973 1276888 Maybridge3_005833 CC(CC(=O)O)CC(=O)Nc1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J04 compound treatment 0.323 0.0174 1.4 0.333 0.0173 1.57 2.0965 0.9984 1266631 Maybridge3_005834 Clc1ccc(CNC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J05 compound treatment 0.32 0.0144 1.16 0.331 0.0153 1.38 1.7973 0.996 2078338 Maybridge3_005835 Fc1ccc(N2C(=O)COCC2=O)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J06 compound treatment 0.331 0.0254 2.04 0.335 0.0193 1.75 2.6804 0.997 1456556 Maybridge3_005836 COc1ccc2cc(ccc2c1)C(C)C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J07 compound treatment 0.311 0.00538 0.43 0.326 0.0103 0.93 0.964 0.9394 1195036 Maybridge3_005837 CNc1nnc(SCc2csc3ccccc23)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J08 compound treatment 0.321 0.0154 1.24 0.338 0.0222 2.02 2.3036 0.9724 2078339 Maybridge3_005838 N#CCC1(C#N)C2CC3CC(C2)CC1C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J09 compound treatment 0.32 0.0144 1.16 0.337 0.0213 1.93 2.1825 0.9702 1674973 Maybridge3_005839 OC(=O)CCSc1ccc2ccccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J10 compound treatment 0.273 -0.0326 -2.63 0.293 -0.0227 -2.07 -3.3179 -0.9929 2078340 Maybridge3_005840 COC(=O)/C(=C\1/C(=O)Nc2ccccc12)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J11 compound treatment 0.323 0.0174 1.4 0.341 0.0253 2.29 2.61 0.972 1500768 Maybridge3_005841 OC(=O)C(C1Sc2ccccc2NC1=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J12 compound treatment 0.32 0.0144 1.16 0.341 0.0253 2.29 2.4392 0.95 2078341 Maybridge3_005842 Fc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J13 compound treatment 0.32 0.0144 1.16 0.337 0.0213 1.93 2.1825 0.9702 2078342 Maybridge3_005843 COc1cc(=O)oc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J14 compound treatment 0.077 -0.229 -18.41 0.085 -0.231 -20.95 -27.8288 -0.9979 2078343 Maybridge3_005844 COc1ccc(CN2C(=O)C=CC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J15 compound treatment 0.319 0.0134 1.08 0.333 0.0173 1.57 1.8688 0.9833 1383942 Maybridge3_005845 NC(=O)c1ccccc1NC(=O)C2C(C3CC2C=C3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J16 compound treatment 0.345 0.0394 3.17 0.358 0.0423 3.84 4.9539 0.9955 1682643 Maybridge3_005846 CC(C)Cc1ccc(cc1)C2=CC(C(C(=O)N)C(=O)N2)c3ccc(C#N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J17 compound treatment 0.317 0.0114 0.92 0.334 0.0182 1.66 1.8191 0.961 2078344 Maybridge3_005847 COc1ccc(Cl)cc1N2C(=O)COCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J18 compound treatment 0.321 0.0154 1.24 0.336 0.0203 1.84 2.1752 0.9815 2078345 Maybridge3_005848 Clc1cc(Cl)cc(c1)N2C(=C)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J19 compound treatment 0.312 0.00638 0.51 0.325 0.00925 0.84 0.9567 0.9721 2078346 Maybridge3_005849 Clc1ccc(cc1)C(=O)CC(C#N)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J20 compound treatment 0.318 0.0124 1.0 0.333 0.0173 1.57 1.8118 0.9762 2078347 Maybridge3_005850 FC(F)(F)c1ccc(NC2=NCCCS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J21 compound treatment 0.329 0.0234 1.88 0.338 0.0222 2.02 2.7591 0.9994 2078348 Maybridge3_005851 CC1CC(=O)N(C1=O)c2ccccc2OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J22 compound treatment 0.333 0.0274 2.2 0.338 0.0222 2.02 2.9869 0.999 2078349 Maybridge3_005852 CC(C)(C)C(=O)CSc1nc(c(C#N)c(=O)[nH]1)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J23 mock treatment 0.305 -6.25E-4 -0.05 0.314 -0.00175 -0.16 -0.1479 -0.8877 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 J24 positive control 0.09 -0.216 -17.36 0.094 -0.222 -20.13 -26.5109 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K01 compound treatment 0.317 0.0114 0.92 0.328 0.0123 1.11 1.434 0.9954 2078350 Maybridge3_005853 C1CN=C(NC2CCCCC2)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K02 compound treatment 0.302 -0.00362 -0.29 0.317 0.00125 0.11 -0.1262 -0.4029 2071140 Maybridge3_005854 Cc1cc(C)c(CSC(=N)N)c(C)c1CSC(=N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K03 compound treatment 0.318 0.0124 1.0 0.33 0.0143 1.29 1.6193 0.9917 2078351 Maybridge3_005855 Cc1ccc(/N=C\2/NCCS2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K04 compound treatment 0.323 0.0174 1.4 0.327 0.0113 1.02 1.7114 0.988 2078352 Maybridge3_005856 C1CN=C(NC2CC3CC2C4C=CCC34)S1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K05 compound treatment 0.33 0.0244 1.96 0.339 0.0233 2.11 2.8802 0.9993 1368985 Maybridge3_005857 Cc1ccc(Cl)cc1N2C(=O)CC(Sc3ccccc3N)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K06 compound treatment 0.32 0.0144 1.16 0.336 0.0203 1.84 2.1183 0.9752 2078353 Maybridge3_005858 CC(=O)NC1=CC(=O)CC(C)(C)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K07 compound treatment 0.074 -0.232 -18.65 0.079 -0.237 -21.49 -28.3847 -0.9975 1083077 Maybridge3_005859 CSc1cccc(c1)N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K08 compound treatment 0.334 0.0284 2.28 0.344 0.0283 2.56 3.4289 0.9983 1230292 Maybridge3_005860 O=C1C(=C(NCc2cccnc2)C#N)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K09 compound treatment 0.314 0.00838 0.67 0.333 0.0173 1.57 1.5841 0.9291 1209524 Maybridge3_005861 COc1cc(cc(OC)c1OC)c2noc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K10 compound treatment 0.325 0.0194 1.56 0.336 0.0203 1.84 2.403 0.9967 1064487 Maybridge3_005862 CN(C)C(=O)c1ccc(cc1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K11 compound treatment 0.321 0.0154 1.24 0.335 0.0193 1.75 2.111 0.9858 2078354 Maybridge3_005863 Cc1ccc(NC(=O)C(F)(F)F)c(c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K12 compound treatment 0.067 -0.239 -19.22 0.073 -0.243 -22.03 -29.1684 -0.9977 2078355 Maybridge3_005864 O=C1C=CC(=O)N1Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K13 compound treatment 0.078 -0.228 -18.33 0.084 -0.232 -21.04 -27.836 -0.9976 1070150 Maybridge3_005865 COC(=O)c1ccccc1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K14 compound treatment 0.322 0.0164 1.32 0.336 0.0203 1.84 2.2322 0.9867 1630954 Maybridge3_005866 Cc1ccc2nc(oc(=O)c2c1)c3ccccc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K15 compound treatment 0.078 -0.228 -18.33 0.084 -0.232 -21.04 -27.836 -0.9976 2078356 Maybridge3_005867 O=C1C=CC(=O)N1Cc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K16 compound treatment 0.321 0.0154 1.24 0.337 0.0213 1.93 2.2394 0.977 1462549 Maybridge3_005868 CC1CN(CC(C)O1)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K17 compound treatment 0.325 0.0194 1.56 0.343 0.0273 2.47 2.8523 0.9753 2078357 Maybridge3_005869 COc1cc(cc(OC)c1OC)C2OC(=O)c3ccccc3S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K18 compound treatment 0.322 0.0164 1.32 0.335 0.0193 1.75 2.168 0.9904 1286809 Maybridge3_005870 O=C1CCC(=O)N1c2ccc(cc2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K19 compound treatment 0.322 0.0164 1.32 0.33 0.0143 1.29 1.847 1.0 2078358 Maybridge3_005871 OC(=O)/C=C/C(=O)Nc1ccnn1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K20 compound treatment 0.323 0.0174 1.4 0.332 0.0163 1.48 2.0324 0.9997 2078359 Maybridge3_005872 Clc1ccc(CCN2C(SCCC2=O)c3cccnc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K21 compound treatment 0.319 0.0134 1.08 0.327 0.0113 1.02 1.4837 0.9996 2078360 Maybridge3_005873 Fc1cccc(c1)n2nnnc2c3ccc(Cl)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K22 compound treatment 0.331 0.0254 2.04 0.338 0.0222 2.02 2.873 1.0 1556396 Maybridge3_005874 Cc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K23 mock treatment 0.307 0.00138 0.11 0.313 -0.00275 -0.25 -0.0982 -0.3597 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 K24 positive control 0.091 -0.215 -17.28 0.096 -0.22 -19.95 -26.3256 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L01 compound treatment 0.326 0.0204 1.64 0.336 0.0203 1.84 2.4599 0.9984 1516643 Maybridge3_005875 Cc1cc(Cl)ccc1NC(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L02 compound treatment 0.322 0.0164 1.32 0.334 0.0182 1.66 2.1038 0.9936 2078361 Maybridge3_005876 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L03 compound treatment 0.324 0.0184 1.48 0.336 0.0203 1.84 2.346 0.9942 1576657 Maybridge3_005877 CC(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L04 compound treatment 0.32 0.0144 1.16 0.328 0.0123 1.11 1.6048 0.9998 1332546 Maybridge3_005878 CCOC(=O)N1C(C=Cc2cc(ccc12)C(C)C)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L05 compound treatment 0.297 -0.00862 -0.69 0.311 -0.00475 -0.43 -0.796 -0.9737 2078362 Maybridge3_005879 CC(=O)Nc1ccc(cc1)C2=N/C(=C/c3cc(Br)cs3)/C(=O)O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L06 compound treatment 0.324 0.0184 1.48 0.337 0.0213 1.93 2.4102 0.9914 2078363 Maybridge3_005880 CCOC(=O)/C(=C/1\CCCc2cc(OC)ccc12)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L07 compound treatment 0.385 0.0794 6.39 0.395 0.0793 7.19 9.6063 0.9983 2078364 Maybridge3_005881 Cc1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L08 compound treatment 0.32 0.0144 1.16 0.332 0.0163 1.48 1.8615 0.9928 2078365 Maybridge3_005882 CCOc1nc2ccc(C)cc2c(=O)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L09 compound treatment 0.318 0.0124 1.0 0.345 0.0293 2.66 2.5821 0.9105 2078366 Maybridge3_005883 COc1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L10 compound treatment 0.32 0.0144 1.16 0.337 0.0213 1.93 2.1825 0.9702 2078367 Maybridge3_005884 O=C1CC(Sc2cccs2)C(=O)N1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L11 compound treatment 0.326 0.0204 1.64 0.342 0.0263 2.38 2.845 0.9834 2078368 Maybridge3_005885 OC(=O)/C=C/C(=O)NCc1csc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L12 compound treatment 0.323 0.0174 1.4 0.336 0.0203 1.84 2.2891 0.9909 2078369 Maybridge3_005886 Cc1ccc2oc(nc2c1)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L13 compound treatment 0.331 0.0254 2.04 0.336 0.0203 1.84 2.7446 0.9986 1438301 Maybridge3_005887 OC(=O)C1C(C2OC1C=C2)C(=O)NCc3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L14 compound treatment 0.328 0.0224 1.8 0.334 0.0182 1.66 2.4454 0.9991 2078370 Maybridge3_005888 COc1ccccc1CNC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L15 compound treatment 0.345 0.0394 3.17 0.355 0.0393 3.56 4.7613 0.9983 1523047 Maybridge3_005889 Fc1ccc(NC(=O)Cc2csc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L16 compound treatment 0.313 0.00738 0.59 0.324 0.00825 0.75 0.9495 0.9934 2078371 Maybridge3_005890 COc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L17 compound treatment 0.328 0.0224 1.8 0.337 0.0213 1.93 2.638 0.9994 1377837 Maybridge3_005891 COc1cc(OC)cc(c1)N2C(=O)CSCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L18 compound treatment 0.317 0.0114 0.92 0.328 0.0123 1.11 1.434 0.9954 2078372 Maybridge3_005892 Fc1ccc(/C=C(\C#N)/c2csc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L19 compound treatment 0.328 0.0224 1.8 0.339 0.0233 2.11 2.7664 0.9969 2078373 Maybridge3_005893 Fc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L20 compound treatment 0.326 0.0204 1.64 0.336 0.0203 1.84 2.4599 0.9984 1698353 Maybridge3_005894 COc1cccc(c1)c2c(C#N)c(=O)[nH]c3CCc4cc(OC)ccc4-c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L21 compound treatment 0.332 0.0264 2.12 0.337 0.0213 1.93 2.8657 0.9988 2078374 Maybridge3_005895 OCC1(CO)CSC(=N1)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L22 compound treatment 0.354 0.0484 3.9 0.359 0.0432 3.93 5.5305 1.0 2078375 Maybridge3_005896 CC(C)(C)c1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L23 mock treatment 0.309 0.00338 0.27 0.318 0.00225 0.2 0.3366 0.9901 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 L24 positive control 0.092 -0.214 -17.2 0.096 -0.22 -19.95 -26.2687 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M01 compound treatment 0.309 0.00338 0.27 0.325 0.00925 0.84 0.7859 0.8905 2078376 Maybridge3_005897 CC1CC(CC(C)(C)C1)/N=C\2/NCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M02 compound treatment 0.08 -0.226 -18.17 0.083 -0.233 -21.13 -27.7864 -0.9972 2078377 Maybridge3_005898 O=C1C=CC(=O)N1c2ccccc2N3CCCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M03 compound treatment 0.315 0.00938 0.75 0.331 0.0153 1.38 1.5126 0.9593 1267614 Maybridge3_005899 COc1ccc(CNc2ccc(cc2)C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M04 compound treatment 0.289 -0.0166 -1.34 0.342 0.0263 2.38 0.7382 0.2701 1015374 Maybridge3_005900 O=C1CSC(=S)N1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M05 compound treatment 0.302 -0.00362 -0.29 0.327 0.0113 1.02 0.5157 0.4855 2078378 Maybridge3_005901 CCc1cccc(CC)c1NC(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M06 compound treatment 0.311 0.00538 0.43 0.324 0.00825 0.75 0.8356 0.966 2078379 Maybridge3_005902 OC(=O)CNC(=O)/C=C/c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M07 compound treatment 0.396 0.0904 7.28 0.411 0.0953 8.65 11.2597 0.9963 2078380 Maybridge3_005903 CCO/C=C/1\SC(=S)N(C1=O)c2ccc(cc2)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M08 compound treatment 0.312 0.00638 0.51 0.331 0.0153 1.38 1.3418 0.9089 2078381 Maybridge3_005904 COc1ccc(Br)c(NC2=NCCS2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M09 compound treatment 0.321 0.0154 1.24 0.332 0.0163 1.48 1.9185 0.9962 2078382 Maybridge3_005905 CCOC(=O)c1ccc(/N=C/c2ccc(Cl)c(Cl)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M10 compound treatment 0.31 0.00438 0.35 0.335 0.0193 1.75 1.4847 0.8329 2078383 Maybridge3_005906 OC(=O)/C=C/C(=O)Nc1cccc2CCCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M11 compound treatment 0.314 0.00838 0.67 0.331 0.0153 1.38 1.4557 0.9454 1048382 Maybridge3_005907 OC(=O)c1ccccc1NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M12 compound treatment 0.312 0.00638 0.51 0.334 0.0182 1.66 1.5344 0.8847 1504168 Maybridge3_005908 O=C(Cc1cccc2ccccc12)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M13 compound treatment 0.315 0.00938 0.75 0.328 0.0123 1.11 1.3201 0.9822 2078384 Maybridge3_005909 OC(=O)/C=C/C(=O)Nc1ccccc1SCc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M14 compound treatment 0.34 0.0344 2.77 0.361 0.0452 4.11 4.8617 0.9816 2078385 Maybridge3_005910 N/C(=C(/N=C/c1cccc(Cl)c1)\C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M15 compound treatment 0.32 0.0144 1.16 0.336 0.0203 1.84 2.1183 0.9752 2078386 Maybridge3_005911 COc1ccc(NC(=O)/C=C/C(=O)O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M16 compound treatment 0.311 0.00538 0.43 0.321 0.00525 0.48 0.643 0.9988 1312957 Maybridge3_005912 NC(=O)CC(CC(=O)N)c1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M17 compound treatment 0.325 0.0194 1.56 0.341 0.0253 2.29 2.7239 0.9824 2078387 Maybridge3_005913 COc1ccc(NC(=O)/C=C/C(=O)O)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M18 compound treatment 0.326 0.0204 1.64 0.328 0.0123 1.11 1.9464 0.982 1710869 Maybridge3_005914 O=C1CCC(=O)N1c2cccc(C#N)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M19 compound treatment 0.456 0.15 12.11 0.473 0.157 14.27 18.6556 0.9967 2078388 Maybridge3_005915 Cc1ccc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)S(=O)(=O)Nc4nccs4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M20 compound treatment 0.318 0.0124 1.0 0.326 0.0103 0.93 1.3625 0.9994 2078389 Maybridge3_005916 OC(=O)C1CSC(N1)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M21 compound treatment 0.306 3.75E-4 0.03 0.317 0.00125 0.11 0.1016 0.8652 2078390 Maybridge3_005917 FC(F)(F)c1ccc(Nc2n[nH]c(=S)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M22 compound treatment 0.328 0.0224 1.8 0.337 0.0213 1.93 2.638 0.9994 2078391 Maybridge3_005918 Cc1cc(/N=C/c2ccccc2O)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M23 mock treatment 0.31 0.00438 0.35 0.312 -0.00375 -0.34 0.0084 0.0172 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 M24 positive control 0.092 -0.214 -17.2 0.098 -0.218 -19.77 -26.1403 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N01 compound treatment 0.326 0.0204 1.64 0.336 0.0203 1.84 2.4599 0.9984 1469510 Maybridge3_005919 OC(=O)COCC(=O)Nc1cccc(C#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N02 compound treatment 0.346 0.0404 3.25 0.356 0.0403 3.65 4.8824 0.9983 2078392 Maybridge3_005920 O/N=C\1/Cc2ccccc2OC1c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N03 compound treatment 0.319 0.0134 1.08 0.322 0.00625 0.57 1.1627 0.9552 1255246 Maybridge3_005921 Clc1ccc(CSC2CC(=O)N(C2=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N04 compound treatment 0.341 0.0354 2.85 0.346 0.0302 2.75 3.9559 0.9998 2078393 Maybridge3_005922 CSc1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N05 compound treatment 0.33 0.0244 1.96 0.332 0.0163 1.48 2.4309 0.9901 1432855 Maybridge3_005923 CCOC(=O)c1ccc(NC(=O)CSCC(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N06 compound treatment 0.325 0.0194 1.56 0.335 0.0193 1.75 2.3388 0.9984 2078394 Maybridge3_005924 N#CCC1(CCCc2ccccc21)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N07 compound treatment 0.33 0.0244 1.96 0.34 0.0243 2.2 2.9444 0.9984 2078395 Maybridge3_005925 O=C/1OC(=N\C1=C/c2ccsc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N08 compound treatment 0.33 0.0244 1.96 0.334 0.0182 1.66 2.5593 0.9964 1473393 Maybridge3_005926 CCN1CCC2(CC1)NC(=O)c3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N09 compound treatment 0.336 0.0304 2.45 0.346 0.0302 2.75 3.6712 0.9983 1185892 Maybridge3_005927 COc1ccc(CNC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N10 compound treatment 0.327 0.0214 1.72 0.337 0.0213 1.93 2.581 0.9984 2078396 Maybridge3_005928 FC(F)(F)Oc1ccccc1NCn2nnc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N11 compound treatment 0.324 0.0184 1.48 0.339 0.0233 2.11 2.5386 0.9849 2078397 Maybridge3_005929 Cc1cc(/C=C/2\N=COC2=O)ccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N12 compound treatment 0.326 0.0204 1.64 0.33 0.0143 1.29 2.0748 0.9931 1728896 Maybridge3_005930 Cc1ccnc(c1)N2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N13 compound treatment 0.355 0.0494 3.98 0.364 0.0483 4.38 5.9084 0.9988 2078398 Maybridge3_005931 CCc1cccc(C)c1NC(=C2C(=O)c3ccccc3C2=O)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N14 compound treatment 0.33 0.0244 1.96 0.341 0.0253 2.29 3.0086 0.997 2078399 Maybridge3_005932 Cc1ccc(CNC(=O)/C=C/C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N15 compound treatment 0.307 0.00138 0.11 0.316 2.5E-4 0.02 0.0943 0.8347 2078400 Maybridge3_005933 Clc1cc(Cl)cc(NC(C#N)c2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N16 compound treatment 0.328 0.0224 1.8 0.341 0.0253 2.29 2.8947 0.9929 2078401 Maybridge3_005934 FC(F)(F)c1ccc(cc1)N2C(=C)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N17 compound treatment 0.325 0.0194 1.56 0.333 0.0173 1.57 2.2104 1.0 2078402 Maybridge3_005935 COc1cc(OC)cc(/C=C/2\N=C(C)OC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N18 compound treatment 0.317 0.0114 0.92 0.331 0.0153 1.38 1.6265 0.9799 1415728 Maybridge3_005936 COc1ccccc1CNc2n[nH]c(=S)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N19 compound treatment 0.326 0.0204 1.64 0.331 0.0153 1.38 2.139 0.9964 1710115 Maybridge3_005937 OC(=O)CSC1CC(=O)N(C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N20 compound treatment 0.326 0.0204 1.64 0.338 0.0222 2.02 2.5883 0.9947 1547948 Maybridge3_005938 Fc1ccc(CN2C(c3cccnc3)S(=O)(=O)CC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N21 compound treatment 0.46 0.154 12.43 0.453 0.137 12.46 17.5996 1.0 2078403 Maybridge3_005939 COc1ccc2C(=O)/C(=C/c3ccc(C)o3)/CCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N22 compound treatment 0.398 0.0924 7.44 0.403 0.0873 7.92 10.8601 0.9995 2078404 Maybridge3_005940 O=C1C(=C(Nc2ccccc2)C#N)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N23 mock treatment 0.315 0.00938 0.75 0.319 0.00325 0.3 0.7424 0.916 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 N24 positive control 0.094 -0.212 -17.04 0.098 -0.218 -19.77 -26.0264 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O01 compound treatment 0.332 0.0264 2.12 0.341 0.0253 2.29 3.1225 0.9993 2078405 Maybridge3_005941 CCOc1ccc(/N=C\2/NCCS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O02 compound treatment 0.348 0.0424 3.41 0.354 0.0382 3.47 4.8679 1.0 2078406 Maybridge3_005942 CCOc1ccc(cc1)C(=O)CC2OC(=O)c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O03 compound treatment 0.32 0.0144 1.16 0.341 0.0253 2.29 2.4392 0.95 1071715 Maybridge3_005943 Cc1cc(CSC(=N)N)c(C)cc1CSC(=N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O04 compound treatment 0.327 0.0214 1.72 0.338 0.0222 2.02 2.6452 0.9968 2078407 Maybridge3_005944 CSc1cccc(c1)N2C(=O)SC(C2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O05 compound treatment 0.324 0.0184 1.48 0.33 0.0143 1.29 1.9609 0.9978 1340187 Maybridge3_005945 Clc1cccc(c1)c2nc3ccccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O06 compound treatment 0.326 0.0204 1.64 0.336 0.0203 1.84 2.4599 0.9984 1288043 Maybridge3_005946 CCOC(=O)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O07 compound treatment 0.422 0.116 9.37 0.422 0.106 9.64 13.4462 0.9999 2078408 Maybridge3_005947 CCO/C=C/1\SC(=S)N(C1=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O08 compound treatment 0.324 0.0184 1.48 0.33 0.0143 1.29 1.9609 0.9978 1435480 Maybridge3_005948 COc1ccc(Br)c(c1)C(=O)NC(C)(C)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O09 compound treatment 0.362 0.0564 4.54 0.374 0.0583 5.29 6.9488 0.9971 2078409 Maybridge3_005949 COc1cc(cc(OC)c1OC)N2C(=O)CSC2=S 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O10 compound treatment 0.074 -0.232 -18.65 0.072 -0.244 -22.13 -28.834 -0.9964 2078410 Maybridge3_005950 O=C1C=CC(=O)N1c2cccc3CCCCc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O11 compound treatment 0.319 0.0134 1.08 0.328 0.0123 1.11 1.5479 0.9999 2078411 Maybridge3_005951 C/C(=N\Cc1ccc(C#N)cc1)/c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O12 compound treatment 0.316 0.0104 0.84 0.323 0.00725 0.66 1.0561 0.993 2078412 Maybridge3_005952 S=c1[nH]nc(NCc2cccs2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O13 compound treatment 0.32 0.0144 1.16 0.335 0.0193 1.75 2.0541 0.98 1553751 Maybridge3_005953 COC(=O)c1ccccc1N2C(=O)CC(Sc3ccccc3N)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O14 compound treatment 0.346 0.0404 3.25 0.358 0.0423 3.84 5.0108 0.9966 2078413 Maybridge3_005954 N/C(=C(/N=C/c1ccccc1)\C#N)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O15 compound treatment 0.325 0.0194 1.56 0.339 0.0233 2.11 2.5955 0.989 2078414 Maybridge3_005955 Cc1onc(c1c2nc3ccccc3c(=O)o2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O16 compound treatment 0.327 0.0214 1.72 0.336 0.0203 1.84 2.5169 0.9995 1459131 Maybridge3_005956 COc1ccc(cc1)c2nc3ccccc3c(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O17 compound treatment 0.104 -0.202 -16.24 0.113 -0.203 -18.4 -24.4942 -0.998 2078415 Maybridge3_005957 CC(C)c1cccc(C(C)C)c1N2C(=O)C=CC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O18 compound treatment 0.321 0.0154 1.24 0.331 0.0153 1.38 1.8543 0.9985 2078416 Maybridge3_005958 CCCc1ccc(cc1)N2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O19 compound treatment 0.325 0.0194 1.56 0.332 0.0163 1.48 2.1462 0.9996 2078417 Maybridge3_005959 Cc1cc(C)nc(/N=C/c2ccccc2O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O20 compound treatment 0.386 0.0804 6.47 0.377 0.0612 5.56 8.508 0.9971 2078418 Maybridge3_005960 Cc1ccc(Nc2nnc(o2)c3ccccc3N)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O21 compound treatment 0.325 0.0194 1.56 0.327 0.0113 1.02 1.8253 0.9789 2078419 Maybridge3_005961 Oc1ccccc1/C=N/c2ccc(Oc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O22 compound treatment 0.338 0.0324 2.61 0.338 0.0222 2.02 3.2716 0.992 2078420 Maybridge3_005962 O=C(NCCc1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O23 mock treatment 0.316 0.0104 0.84 0.32 0.00425 0.39 0.8635 0.9384 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 O24 positive control 0.094 -0.212 -17.04 0.098 -0.218 -19.77 -26.0264 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P01 compound treatment 0.308 0.00238 0.19 0.326 0.0103 0.93 0.7931 0.835 2078421 Maybridge3_005963 O=C1CSC(=S)N1CC2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P02 compound treatment 0.336 0.0304 2.45 0.339 0.0233 2.11 3.2219 0.9973 2078422 Maybridge3_005964 Clc1ccc(cc1)C(=O)CC(C(C#N)C#N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P03 compound treatment 0.334 0.0284 2.28 0.342 0.0263 2.38 3.3006 0.9998 1507005 Maybridge3_005965 CC(=O)SC1CC(=O)N(C1=O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P04 compound treatment 0.355 0.0494 3.98 0.364 0.0483 4.38 5.9084 0.9988 2078423 Maybridge3_005966 FC(F)(F)Oc1ccc(NC(=O)C#Cc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P05 compound treatment 0.323 0.0174 1.4 0.327 0.0113 1.02 1.7114 0.988 1331738 Maybridge3_005967 CCOC(=O)c1ccc(cc1)N2C(=O)CSCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P06 compound treatment 0.327 0.0214 1.72 0.331 0.0153 1.38 2.1959 0.9942 2078424 Maybridge3_005968 CCOC(=O)/C(=C/1\CCc2ccccc12)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P07 compound treatment 0.348 0.0424 3.41 0.358 0.0423 3.84 5.1247 0.9983 2078425 Maybridge3_005969 Oc1ccc(Cl)cc1NC(=C2C(=O)c3ccccc3C2=O)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P08 compound treatment 0.356 0.0504 4.06 0.361 0.0452 4.11 5.7728 1.0 1610166 Maybridge3_005970 Clc1ccc(NC2CC(=O)N(C2=O)c3ccc(Cl)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P09 compound treatment 0.328 0.0224 1.8 0.332 0.0163 1.48 2.3171 0.9951 1620166 Maybridge3_005971 CC(C)(CC(=O)O)CC(=O)Nc1cc(Cl)ccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P10 compound treatment 0.325 0.0194 1.56 0.327 0.0113 1.02 1.8253 0.9789 2078426 Maybridge3_005972 FC(F)(F)Oc1ccc(NCn2nnc3cc(Cl)ccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P11 compound treatment 0.322 0.0164 1.32 0.323 0.00725 0.66 1.3977 0.9484 1544733 Maybridge3_005973 CC(C)(C)c1cccc(c1O)C2(O)C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P12 compound treatment 0.323 0.0174 1.4 0.328 0.0123 1.11 1.7756 0.9935 1311154 Maybridge3_005974 OC(=O)COCC(=O)Nc1ccccn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P13 compound treatment 0.364 0.0584 4.7 0.365 0.0493 4.47 6.485 0.9997 2078427 Maybridge3_005975 Cc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccccc3)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P14 compound treatment 0.096 -0.21 -16.88 0.1 -0.216 -19.58 -25.7842 -0.9973 1081390 Maybridge3_005976 Cc1ccc(CN2C(=O)C=CC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P15 compound treatment 0.315 0.00938 0.75 0.323 0.00725 0.66 0.9992 0.9977 2078428 Maybridge3_005977 Cc1ccc(Cl)cc1NC(C#N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P16 compound treatment 0.32 0.0144 1.16 0.327 0.0113 1.02 1.5406 0.998 2078429 Maybridge3_005978 Fc1ccc(cc1)N2C(=C)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P17 compound treatment 0.32 0.0144 1.16 0.327 0.0113 1.02 1.5406 0.998 1662322 Maybridge3_005979 Cc1ccc(cc1)S(=O)(=O)NCCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P18 compound treatment 0.319 0.0134 1.08 0.329 0.0133 1.2 1.612 0.9985 2078430 Maybridge3_005980 Cc1ccc(CNC2=NCCS2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P19 compound treatment 0.326 0.0204 1.64 0.332 0.0163 1.48 2.2032 0.9986 2078431 Maybridge3_005981 CC(SC1CC(=O)N(C1=O)c2ccccc2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P20 compound treatment 0.343 0.0374 3.01 0.347 0.0313 2.84 4.1339 0.9996 2078432 Maybridge3_005982 C=CCOc1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P21 compound treatment 0.328 0.0224 1.8 0.334 0.0182 1.66 2.4454 0.9991 2078433 Maybridge3_005983 Cc1cc(C)c(NC2=NC(CO)(CO)CS2)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P22 compound treatment 0.331 0.0254 2.04 0.335 0.0193 1.75 2.6804 0.997 2078434 Maybridge3_005984 O=C/1C2CCN(CC2)\C1=C\c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P23 mock treatment 0.312 0.00638 0.51 0.322 0.00625 0.57 0.7642 0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1447 P24 positive control 0.096 -0.21 -16.88 0.099 -0.217 -19.67 -25.8483 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A01 compound treatment 0.317 0.0129 1.04 0.315 0.0187 1.7 1.9401 0.9723 2078435 Maybridge3_005985 CCCSC(=S)c1c(C)nn(c1O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A02 compound treatment 0.308 0.00394 0.32 0.312 0.0158 1.43 1.2351 0.8434 2078436 Maybridge3_005986 CC1(C)Cc2cccc(C(=O)Nc3ccncc3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A03 compound treatment 0.293 -0.0111 -0.89 0.297 7.5E-4 0.07 -0.5818 -0.6512 2078437 Maybridge3_005987 NC(=O)c1cnn2C(=CCNc12)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A04 compound treatment 0.305 9.37E-4 0.08 0.309 0.0127 1.16 0.8717 0.7516 2078438 Maybridge3_005988 CC1(C)Cc2cccc(C(=O)Nc3ccc(cc3)c4csnn4)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A05 compound treatment 0.306 0.00194 0.16 0.307 0.0107 0.98 0.8003 0.8099 2078439 Maybridge3_005989 COC(=O)c1sccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A06 compound treatment 0.304 -6.25E-5 -0.01 0.301 0.00475 0.43 0.3013 0.6988 2078440 Maybridge3_005990 Fc1cc(C(=O)NCc2csc3ccccc23)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A07 compound treatment 0.305 9.37E-4 0.08 0.3 0.00375 0.34 0.2941 0.8434 2078441 Maybridge3_005991 Cc1ccccc1NC(=O)c2ccc3ncsc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A08 compound treatment 0.303 -0.00106 -0.09 0.3 0.00375 0.34 0.1802 0.5134 2078442 Maybridge3_005992 Fc1cc(C(=O)NC2CC2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A09 compound treatment 0.32 0.0159 1.28 0.32 0.0238 2.16 2.4319 0.9693 2078443 Maybridge3_005993 Cc1onc(c1CNC(=O)c2c(C)onc2c3ccc(F)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A10 compound treatment 0.303 -0.00106 -0.09 0.3 0.00375 0.34 0.1802 0.5134 2078444 Maybridge3_005994 Cc1cc(nn1C)C(=O)NCc2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A11 compound treatment 0.304 -6.25E-5 -0.01 0.304 0.00775 0.7 0.4939 0.702 2078445 Maybridge3_005995 CC(=O)N1CCC(CC1)C(=O)Nc2ccc(cc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A12 compound treatment 0.339 0.0349 2.81 0.335 0.0388 3.52 4.4765 0.9939 2078446 Maybridge3_005996 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)N3CCN(Cc4cccnc4)CC3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A13 compound treatment 0.328 0.0239 1.93 0.325 0.0288 2.61 3.2083 0.9889 2078447 Maybridge3_005997 Ic1ccc(NC(=O)CCC(=O)N2CCc3ccccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A14 compound treatment 0.314 0.00994 0.8 0.314 0.0177 1.61 1.7051 0.9478 2078448 Maybridge3_005998 CN(Cc1ccccc1)S(=O)(=O)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A15 compound treatment 0.303 -0.00106 -0.09 0.303 0.00675 0.61 0.3727 0.6025 2078449 Maybridge3_005999 FC(F)(F)c1nn(c2ccncc12)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A16 compound treatment 0.318 0.0139 1.12 0.302 0.00575 0.52 1.1627 0.9393 2078450 Maybridge3_006000 Cc1nc(C)c(s1)S(=O)(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A17 compound treatment 0.308 0.00394 0.32 0.304 0.00775 0.7 0.7216 0.9352 2078451 Maybridge3_006001 OC(=O)CC1(CC(=O)NCc2ccco2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A18 compound treatment 0.307 0.00294 0.24 0.304 0.00775 0.7 0.6647 0.8956 2078452 Maybridge3_006002 O=S(=O)(NCCc1ccccn1)c2ccc(s2)c3ccon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A19 compound treatment 0.306 0.00194 0.16 0.304 0.00775 0.7 0.6078 0.8434 2078453 Maybridge3_006003 Cn1nccc1NC(=O)CC2(CC(=O)O)CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A20 compound treatment 0.308 0.00394 0.32 0.304 0.00775 0.7 0.7216 0.9352 2078454 Maybridge3_006004 O=C(NCc1csc(n1)c2cccs2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A21 compound treatment 0.312 0.00794 0.64 0.311 0.0147 1.34 1.3987 0.9428 2078455 Maybridge3_006005 Clc1ccc(CS(=O)(=O)N2CCN(CC2)c3ncccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A22 compound treatment 0.3 -0.00406 -0.33 0.3 0.00375 0.34 0.0094 0.0199 2078456 Maybridge3_006006 O=C(NCc1csc(n1)c2cccs2)C3=Cc4ccccc4OC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A23 mock treatment 0.297 -0.00706 -0.57 0.291 -0.00525 -0.48 -0.7391 -0.9961 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 A24 positive control 0.089 -0.215 -17.32 0.084 -0.212 -19.27 -25.8691 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B01 compound treatment 0.327 0.0229 1.85 0.329 0.0328 2.97 3.4081 0.9738 2078457 Maybridge3_006007 O=C(N1CCOCC1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B02 compound treatment 0.325 0.0209 1.69 0.326 0.0297 2.7 3.1017 0.9743 1415468 Maybridge3_006008 CC(C)(C)C(=O)NCc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B03 compound treatment 0.321 0.0169 1.36 0.316 0.0198 1.79 2.2321 0.9909 2078458 Maybridge3_006009 O=C(NCc1ccc2OCCc2c1)C3=Cc4ccccc4OC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B04 compound treatment 0.084 -0.22 -17.72 0.085 -0.211 -19.18 -26.0896 -0.9992 2078459 Maybridge3_006010 O=C1C=CC(=O)N1c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B05 compound treatment 0.323 0.0189 1.52 0.311 0.0147 1.34 2.025 0.9979 2078460 Maybridge3_006011 COc1ccc(OC)c(c1)S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B06 compound treatment 0.23 -0.0741 -5.96 0.238 -0.0583 -5.29 -7.956 -0.9982 1268166 Maybridge3_006012 COc1ccc(cc1OC)c2cc(=S)sc(N)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B07 compound treatment 0.312 0.00794 0.64 0.313 0.0168 1.52 1.5271 0.9259 2078461 Maybridge3_006013 Cc1cc(c(C)s1)S(=O)(=O)NCc2nn(nc2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B08 compound treatment 0.324 0.0199 1.61 0.317 0.0208 1.88 2.4671 0.9968 2078462 Maybridge3_006014 Clc1ccc(/C=N/c2ccc(cc2)c3cnco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B09 compound treatment 0.322 0.0179 1.44 0.318 0.0217 1.97 2.4174 0.9882 1200711 Maybridge3_006015 CSc1nc(NC(=O)C(C)C)c(C#N)n1Cc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B10 compound treatment 0.32 0.0159 1.28 0.316 0.0198 1.79 2.1751 0.9866 2078463 Maybridge3_006016 Nc1cccc(c1)c2ncon2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B11 compound treatment 0.317 0.0129 1.04 0.318 0.0217 1.97 2.1327 0.9554 2078464 Maybridge3_006017 CSc1nsc(SC)c1C(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B12 compound treatment 0.327 0.0229 1.85 0.328 0.0318 2.88 3.344 0.9769 1610905 Maybridge3_006018 CCOC(=O)c1csc(Cc2ccc(cc2)c3csnn3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B13 compound treatment 0.324 0.0199 1.61 0.31 0.0138 1.25 2.0178 0.9922 2078465 Maybridge3_006019 CCOC(=O)CSCc1noc(COc2ccc(Cl)cc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B14 compound treatment 0.325 0.0209 1.69 0.311 0.0147 1.34 2.1389 0.9935 2078466 Maybridge3_006020 COC(=O)c1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B15 compound treatment 0.369 0.0649 5.23 0.364 0.0678 6.15 8.0461 0.9967 2078467 Maybridge3_006021 CCOC(=O)/C=C/1\CSCC(N1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B16 compound treatment 0.319 0.0149 1.2 0.317 0.0208 1.88 2.1824 0.9765 1473233 Maybridge3_006022 Fc1ccc(OCCC(=O)Nc2nccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B17 compound treatment 0.341 0.0369 2.97 0.328 0.0318 2.88 4.1411 0.9999 2078468 Maybridge3_006023 Cc1ccc(SC(=O)c2csnn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B18 compound treatment 0.323 0.0189 1.52 0.319 0.0227 2.07 2.5385 0.9889 2078469 Maybridge3_006024 Cn1c(SCc2ccc(cc2)c3nnco3)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B19 compound treatment 0.318 0.0139 1.12 0.315 0.0187 1.7 1.9971 0.9796 2078470 Maybridge3_006025 Nc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B20 compound treatment 0.355 0.0509 4.1 0.352 0.0558 5.06 6.4787 0.9946 2078471 Maybridge3_006026 O=S(=O)(/C(=C/c1cc2ccccc2o1)/C#N)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B21 compound treatment 0.319 0.0149 1.2 0.319 0.0227 2.07 2.3108 0.9669 2078472 Maybridge3_006027 CCn1cc(C(=O)OC)c(=O)c2cc(ccc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B22 compound treatment 0.325 0.0209 1.69 0.319 0.0227 2.07 2.6524 0.9949 2078473 Maybridge3_006028 CSC(=O)NC(=O)c1cccc(=O)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B23 mock treatment 0.306 0.00194 0.16 0.299 0.00275 0.25 0.2868 0.9744 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 B24 positive control 0.087 -0.217 -17.48 0.086 -0.21 -19.08 -25.8546 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C01 compound treatment 0.313 0.00894 0.72 0.318 0.0217 1.97 1.9049 0.9065 2078474 Maybridge3_006029 Cc1cccc(c1)c2nc3cc(C)ccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C02 compound treatment 0.321 0.0169 1.36 0.329 0.0328 2.97 3.0665 0.9376 2078475 Maybridge3_006030 CC1(C)Cc2cccc(C(=O)NCc3cccnc3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C03 compound treatment 0.314 0.00994 0.8 0.304 0.00775 0.7 1.0633 0.9979 1010943 Maybridge3_006031 OC(=O)c1cncc(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C04 compound treatment 0.348 0.0439 3.54 0.352 0.0558 5.06 6.0802 0.9847 2078476 Maybridge3_006032 Cc1ccc2cc(NC(=O)c3cccc4CC(C)(C)Oc43)ccc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C05 compound treatment 0.317 0.0129 1.04 0.308 0.0118 1.07 1.4908 0.9999 1007291 Maybridge3_006033 Cc1ccc(C(=O)O)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C06 compound treatment 0.316 0.0119 0.96 0.315 0.0187 1.7 1.8832 0.9634 2078477 Maybridge3_006034 Fc1cc(C(=O)NCc2cccs2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C07 compound treatment 0.334 0.0299 2.41 0.315 0.0187 1.7 2.9081 0.9855 2078478 Maybridge3_006035 FC(F)(F)c1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C08 compound treatment 0.324 0.0199 1.61 0.321 0.0248 2.25 2.7238 0.9864 2078479 Maybridge3_006036 O=C(NCC1CCCO1)c2cccc3OCCCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C09 compound treatment 0.325 0.0209 1.69 0.311 0.0147 1.34 2.1389 0.9935 2078480 Maybridge3_006037 Cc1onc(c1CNC(=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C10 compound treatment 0.31 0.00594 0.48 0.307 0.0107 0.98 1.0281 0.9461 2078481 Maybridge3_006038 CN1CCN(CC1)c2ccc(CNC(=O)c3cc4c(C)nn(C)c4s3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C11 compound treatment 0.32 0.0159 1.28 0.313 0.0168 1.52 1.9826 0.9964 2078482 Maybridge3_006039 CC(=O)N1CCC(CC1)C(=O)NCc2ccc(cc2)n3cccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C12 compound treatment 0.313 0.00894 0.72 0.316 0.0198 1.79 1.7766 0.9196 2078483 Maybridge3_006040 O=C(NCc1csc(n1)c2cccs2)c3nc4ccccc4s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C13 compound treatment 0.369 0.0649 5.23 0.359 0.0628 5.7 7.7252 0.9991 2078484 Maybridge3_006041 COC(=O)C1=CC=C(SC1)c2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C14 compound treatment 0.326 0.0219 1.77 0.327 0.0308 2.79 3.2228 0.9756 2078485 Maybridge3_006042 CC1CCCN(C1)S(=O)(=O)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C15 compound treatment 0.324 0.0199 1.61 0.308 0.0118 1.07 1.8894 0.9803 2078486 Maybridge3_006043 Cc1ccc(cc1)S(=O)(=O)n2nc(c3cnccc23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C16 compound treatment 0.304 -6.25E-5 -0.01 0.307 0.0107 0.98 0.6864 0.7035 2078487 Maybridge3_006044 CN1CCOc2cc(ccc12)S(=O)(=O)NCc3csc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C17 compound treatment 0.326 0.0219 1.77 0.313 0.0168 1.52 2.3242 0.9972 2078488 Maybridge3_006045 OC(=O)CC1(CC(=O)NCc2ccoc2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C18 compound treatment 0.327 0.0229 1.85 0.325 0.0288 2.61 3.1514 0.9857 2078489 Maybridge3_006046 O=C(NCCc1ccccn1)c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C19 compound treatment 0.328 0.0239 1.93 0.314 0.0177 1.61 2.5023 0.996 2078490 Maybridge3_006047 OC(=O)CC1(CC(=O)Nc2cscc2S(=O)(=O)c3ccccc3)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C20 compound treatment 0.313 0.00894 0.72 0.319 0.0227 2.07 1.9691 0.9004 2078491 Maybridge3_006048 CCC(=O)NCc1csc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C21 compound treatment 0.319 0.0149 1.2 0.31 0.0138 1.25 1.7331 0.9998 2078492 Maybridge3_006049 Clc1ccc(CS(=O)(=O)NCc2cccnc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C22 compound treatment 0.308 0.00394 0.32 0.316 0.0198 1.79 1.4919 0.8195 2078493 Maybridge3_006050 O=C(Cc1cccc2ccccc12)NCc3csc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C23 mock treatment 0.302 -0.00206 -0.17 0.29 -0.00625 -0.57 -0.5186 -0.8773 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 C24 positive control 0.09 -0.214 -17.24 0.087 -0.209 -18.99 -25.6196 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D01 compound treatment 0.335 0.0309 2.49 0.333 0.0367 3.34 4.1204 0.9897 2078494 Maybridge3_006051 O=C(N1CCCC1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D02 compound treatment 0.324 0.0199 1.61 0.326 0.0297 2.7 3.0448 0.9692 1296331 Maybridge3_006052 O=C(NCc1ccc(cc1)c2csnn2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D03 compound treatment 0.334 0.0299 2.41 0.326 0.0297 2.7 3.6142 0.9984 2078495 Maybridge3_006053 Cn1nc(cc1C(=O)NCc2ccc3OCCc3c2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D04 compound treatment 0.324 0.0199 1.61 0.315 0.0187 1.7 2.3387 0.9996 1522139 Maybridge3_006054 O=C1CSC(N1c2ccc(cc2)c3csnn3)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D05 compound treatment 0.321 0.0169 1.36 0.323 0.0267 2.43 2.6814 0.9628 2078496 Maybridge3_006055 Cc1nn(C)c(C)c1S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D06 compound treatment 0.325 0.0209 1.69 0.329 0.0328 2.97 3.2943 0.9639 1649031 Maybridge3_006056 Cc1ccccc1C(=O)Oc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D07 compound treatment 0.328 0.0239 1.93 0.323 0.0267 2.43 3.08 0.9935 2078497 Maybridge3_006057 CCOC(=O)c1nnn(c1O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D08 compound treatment 0.325 0.0209 1.69 0.323 0.0267 2.43 2.9091 0.9841 2078498 Maybridge3_006058 C(=N/c1ccc(cc1)c2cnco2)\c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D09 compound treatment 0.33 0.0259 2.09 0.319 0.0227 2.07 2.9371 1.0 2078499 Maybridge3_006059 CSc1nsc(SC)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D10 compound treatment 0.335 0.0309 2.49 0.335 0.0388 3.52 4.2488 0.9857 2078500 Maybridge3_006060 Clc1ccc(cc1)C(=O)Nc2cccc(c2)c3ncon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D11 compound treatment 0.34 0.0359 2.89 0.326 0.0297 2.7 3.9558 0.9994 1283284 Maybridge3_006061 CCOC(=O)C1CCCCN1C(=O)c2c(SC)nsc2SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D12 compound treatment 0.332 0.0279 2.25 0.326 0.0297 2.7 3.5003 0.9959 1670723 Maybridge3_006062 CC(C)c1ccc(NC(=O)c2ccc(cc2)c3csnn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D13 compound treatment 0.32 0.0159 1.28 0.315 0.0187 1.7 2.111 0.9903 2078501 Maybridge3_006063 Cc1nnsc1c2nc(CSc3ccc(Cl)cc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D14 compound treatment 0.329 0.0249 2.01 0.324 0.0278 2.52 3.2011 0.9937 2078502 Maybridge3_006064 CCOC(=O)c1ncoc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D15 compound treatment 0.319 0.0149 1.2 0.32 0.0238 2.16 2.3749 0.962 1058745 Maybridge3_006065 c1snnc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D16 compound treatment 0.326 0.0219 1.77 0.317 0.0208 1.88 2.581 0.9995 1357596 Maybridge3_006066 Fc1ccc(OCCC(=O)N2CCSCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D17 compound treatment 0.324 0.0199 1.61 0.316 0.0198 1.79 2.4029 0.9985 2078503 Maybridge3_006067 Clc1ccc(OC(=O)c2csnn2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D18 compound treatment 0.322 0.0179 1.44 0.329 0.0328 2.97 3.1234 0.945 1168977 Maybridge3_006068 O=C(Oc1ccc(cc1)c2csnn2)c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D19 compound treatment 0.319 0.0149 1.2 0.314 0.0177 1.61 1.9898 0.9896 1205634 Maybridge3_006069 Cc1noc(C)c1c2nc(CSc3ccc(C)cc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D20 compound treatment 0.352 0.0479 3.86 0.342 0.0457 4.15 5.6661 0.9993 2078504 Maybridge3_006070 CC(C)(C)S(=O)(=O)/C(=C/c1cc2ccccc2o1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D21 compound treatment 0.311 0.00694 0.56 0.316 0.0198 1.79 1.6627 0.8855 2078505 Maybridge3_006071 Cc1noc(C)c1c2nc(CSCc3ccc(Cl)cc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D22 compound treatment 0.326 0.0219 1.77 0.318 0.0217 1.97 2.6452 0.9985 2078506 Maybridge3_006072 C/C(=N\O)/c1oc(C)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D23 mock treatment 0.299 -0.00506 -0.41 0.3 0.00375 0.34 -0.0476 -0.0896 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 D24 positive control 0.09 -0.214 -17.24 0.088 -0.208 -18.9 -25.5554 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E01 compound treatment 0.328 0.0239 1.93 0.33 0.0338 3.06 3.5293 0.9751 2078507 Maybridge3_006073 Cc1ccc2oc(nc2c1)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E02 compound treatment 0.314 0.00994 0.8 0.315 0.0187 1.7 1.7693 0.9408 2078508 Maybridge3_006074 CC1(C)Cc2cccc(C(=O)Nc3ccc(F)cc3F)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E03 compound treatment 0.324 0.0199 1.61 0.317 0.0208 1.88 2.4671 0.9968 1032444 Maybridge3_006075 CC(=O)Oc1c(C)cccc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E04 compound treatment 0.328 0.0239 1.93 0.319 0.0227 2.07 2.8232 0.9994 2078509 Maybridge3_006076 CC1(C)Cc2cccc(C(=O)Nc3cccnc3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E05 compound treatment 0.329 0.0249 2.01 0.32 0.0238 2.16 2.9444 0.9994 1323327 Maybridge3_006077 CN(C(=O)C)c1cccc(c1)c2ccc3nnc(C)n3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E06 compound treatment 0.322 0.0179 1.44 0.311 0.0147 1.34 1.9681 0.9993 2078510 Maybridge3_006078 Fc1cc(C(=O)NCc2csc(n2)c3ccccc3)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E07 compound treatment 0.324 0.0199 1.61 0.324 0.0278 2.52 2.9164 0.9763 2078511 Maybridge3_006079 Cc1onc(c1CNC(=O)C2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E08 compound treatment 0.33 0.0259 2.09 0.316 0.0198 1.79 2.7446 0.9971 2078512 Maybridge3_006080 O=C(NCc1ccc2OCOc2c1)c3cccc4OCCCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E09 compound treatment 0.326 0.0219 1.77 0.321 0.0248 2.25 2.8377 0.9929 2078513 Maybridge3_006081 Cc1onc(c1CNC(=O)CCC(=O)O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E10 compound treatment 0.328 0.0239 1.93 0.321 0.0248 2.25 2.9516 0.9971 2078514 Maybridge3_006082 CN1CCN(CC1)c2ccc(CNC(=O)c3snnc3C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E11 compound treatment 0.329 0.0249 2.01 0.32 0.0238 2.16 2.9444 0.9994 2078515 Maybridge3_006083 CC(=O)N1CCC(CC1)C(=O)Nc2ccc(cc2)c3cnco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E12 compound treatment 0.358 0.0539 4.34 0.332 0.0357 3.25 5.3659 0.9897 2078516 Maybridge3_006084 Cc1nccc(n1)c2cccc(NC(=O)c3nc4ccccc4s3)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E13 compound treatment 0.305 9.37E-4 0.08 0.292 -0.00425 -0.39 -0.2194 -0.5581 2078517 Maybridge3_006085 CCc1c(C)c(C)[nH]c1C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E14 compound treatment 0.327 0.0229 1.85 0.316 0.0198 1.79 2.5737 0.9999 2078518 Maybridge3_006086 O=S(=O)(N1CCSCC1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E15 compound treatment 0.325 0.0209 1.69 0.322 0.0257 2.34 2.845 0.9871 2078519 Maybridge3_006087 COc1ccc(CNC(=O)CC2(CC(=O)O)CCCCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E16 compound treatment 0.311 0.00694 0.56 0.31 0.0138 1.25 1.2776 0.9343 2078520 Maybridge3_006088 Cc1c(cnn1c2ccccc2)S(=O)(=O)NCc3csc(n3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E17 compound treatment 0.328 0.0239 1.93 0.325 0.0288 2.61 3.2083 0.9889 2078521 Maybridge3_006089 OC(=O)CC1(CC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E18 compound treatment 0.333 0.0289 2.33 0.329 0.0328 2.97 3.7498 0.9927 2078522 Maybridge3_006090 COc1ccc(cc1)n2ncc(C(=O)NCCc3ccccn3)c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E19 compound treatment 0.316 0.0119 0.96 0.314 0.0177 1.61 1.819 0.9695 2078523 Maybridge3_006091 OC(=O)CC1(CC(=O)Nc2ccc3COC(=O)c3c2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E20 compound treatment 0.321 0.0169 1.36 0.323 0.0267 2.43 2.6814 0.9628 2078524 Maybridge3_006092 COc1ccccc1CC(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E21 compound treatment 0.318 0.0139 1.12 0.321 0.0248 2.25 2.3822 0.9486 2078525 Maybridge3_006093 Clc1ccc(CS(=O)(=O)NCc2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E22 compound treatment 0.318 0.0139 1.12 0.309 0.0127 1.16 1.612 0.9999 2078526 Maybridge3_006094 O=C(NCc1csc(n1)c2cccs2)C3CCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E23 mock treatment 0.298 -0.00606 -0.49 0.291 -0.00525 -0.48 -0.6822 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 E24 positive control 0.093 -0.211 -17.0 0.091 -0.205 -18.63 -25.1921 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F01 compound treatment 0.33 0.0259 2.09 0.325 0.0288 2.61 3.3222 0.9939 2078527 Maybridge3_006095 COc1ccc(NC(=O)c2ccc(nc2)N3CCOCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F02 compound treatment 0.327 0.0229 1.85 0.323 0.0267 2.43 3.023 0.9909 2078528 Maybridge3_006096 C=CC(=O)NCc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F03 compound treatment 0.323 0.0189 1.52 0.316 0.0198 1.79 2.346 0.9968 2078529 Maybridge3_006097 Cc1ccc(cc1C)C(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F04 compound treatment 0.325 0.0209 1.69 0.324 0.0278 2.52 2.9733 0.9809 2078530 Maybridge3_006098 O=C(NCCc1cccs1)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F05 compound treatment 0.332 0.0279 2.25 0.32 0.0238 2.16 3.1152 0.9998 2078531 Maybridge3_006099 Cc1nc(C)c(s1)S(=O)(=O)NCc2ccc(cc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F06 compound treatment 0.334 0.0299 2.41 0.322 0.0257 2.34 3.3574 0.9999 1690021 Maybridge3_006100 Cc1noc(C)c1C(=O)Oc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F07 compound treatment 0.338 0.0339 2.73 0.315 0.0187 1.7 3.1359 0.974 2078532 Maybridge3_006101 CCOC(=O)c1nnn(c1Sc2ccccn2)c3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F08 compound treatment 0.315 0.0109 0.88 0.316 0.0198 1.79 1.8904 0.9464 2078533 Maybridge3_006102 FC(F)(F)c1ccc(cc1)C2NCCc3sccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F09 compound treatment 0.321 0.0169 1.36 0.323 0.0267 2.43 2.6814 0.9628 2078534 Maybridge3_006103 CSc1nsc(SC)c1CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F10 compound treatment 0.329 0.0249 2.01 0.312 0.0158 1.43 2.4309 0.9861 1426938 Maybridge3_006104 CC(C)(C)C(=O)Nc1cccc(c1)c2ncon2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F11 compound treatment 0.324 0.0199 1.61 0.32 0.0238 2.16 2.6597 0.9895 2078535 Maybridge3_006105 Clc1ccc(SCc2ncon2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F12 compound treatment 0.328 0.0239 1.93 0.326 0.0297 2.7 3.2725 0.9863 1354010 Maybridge3_006106 COc1ccccc1NC(=O)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F13 compound treatment 0.329 0.0249 2.01 0.317 0.0208 1.88 2.7518 0.9995 2078536 Maybridge3_006107 Cc1nnsc1c2nc(CSc3ccccn3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F14 compound treatment 0.332 0.0279 2.25 0.333 0.0367 3.34 3.9496 0.9816 2078537 Maybridge3_006108 CCOC(=O)c1ncoc1c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F15 compound treatment 0.319 0.0149 1.2 0.311 0.0147 1.34 1.7973 0.9986 1380935 Maybridge3_006109 CC(C)(C)c1ccc(s1)c2nc(CSc3ccccn3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F16 compound treatment 0.331 0.0269 2.17 0.334 0.0377 3.43 3.9568 0.9757 2078538 Maybridge3_006110 Cn1c(SCc2ccc(cc2)c3csnn3)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F17 compound treatment 0.323 0.0189 1.52 0.316 0.0198 1.79 2.346 0.9968 2078539 Maybridge3_006111 CCCS(=O)(=O)/C(=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F18 compound treatment 0.506 0.202 16.26 0.49 0.194 17.59 23.9343 0.9992 2078540 Maybridge3_006112 O=C(Sc1ccccc1)c2cccc(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F19 compound treatment 0.329 0.0249 2.01 0.318 0.0217 1.97 2.816 1.0 1648307 Maybridge3_006113 O=C(Nc1ccc(cc1)c2csnn2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F20 compound treatment 0.325 0.0209 1.69 0.325 0.0288 2.61 3.0375 0.9777 2078541 Maybridge3_006114 Cc1nc(C)c(o1)c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F21 compound treatment 0.33 0.0259 2.09 0.327 0.0308 2.79 3.4506 0.9898 2078542 Maybridge3_006115 FC(F)(F)c1ccccc1C(=O)NCc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F22 compound treatment 0.31 0.00594 0.48 0.313 0.0168 1.52 1.4132 0.8867 2078543 Maybridge3_006116 Clc1ccc(SCc2ccsc2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F23 mock treatment 0.303 -0.00106 -0.09 0.294 -0.00225 -0.2 -0.2049 -0.9254 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 F24 positive control 0.092 -0.212 -17.08 0.093 -0.203 -18.45 -25.1206 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G01 compound treatment 0.327 0.0229 1.85 0.315 0.0187 1.7 2.5096 0.9992 1043122 Maybridge3_006117 COc1ccc(cc1)C(=O)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G02 compound treatment 0.322 0.0179 1.44 0.32 0.0238 2.16 2.5458 0.981 2078544 Maybridge3_006118 CC1(C)Cc2cccc(C(=O)Nc3ccc(cc3)S(=O)(=O)N)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G03 compound treatment 0.32 0.0159 1.28 0.319 0.0227 2.07 2.3677 0.9738 1354713 Maybridge3_006119 CCCC(=O)c1ccc(NC(=O)C)cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G04 compound treatment 0.331 0.0269 2.17 0.325 0.0288 2.61 3.3792 0.9958 2078545 Maybridge3_006120 Cn1nccc1NC(=O)c2cccc3CC(C)(C)Oc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G05 compound treatment 0.324 0.0199 1.61 0.32 0.0238 2.16 2.6597 0.9895 2078546 Maybridge3_006121 CCCCc1nc(CO)c[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G06 compound treatment 0.326 0.0219 1.77 0.319 0.0227 2.07 2.7094 0.997 2078547 Maybridge3_006122 Fc1cc(C(=O)NCc2ccc(cc2)n3cccn3)c4OCOCc4c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G07 compound treatment 0.324 0.0199 1.61 0.319 0.0227 2.07 2.5955 0.9923 2078548 Maybridge3_006123 Cc1onc(c1CNC(=O)C2CC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G08 compound treatment 0.324 0.0199 1.61 0.322 0.0257 2.34 2.788 0.9832 2078549 Maybridge3_006124 COc1cccc(NC(=O)c2cccc3OCCCOc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G09 compound treatment 0.312 0.00794 0.64 0.313 0.0168 1.52 1.5271 0.9259 2078550 Maybridge3_006125 Cc1onc(c1CNS(=O)(=O)c2ccc(C)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G10 compound treatment 0.323 0.0189 1.52 0.315 0.0187 1.7 2.2818 0.9985 2078551 Maybridge3_006126 CN1CCN(CC1)c2ccc(CNC(=O)c3ccno3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G11 compound treatment 0.315 0.0109 0.88 0.315 0.0187 1.7 1.8263 0.953 2078552 Maybridge3_006127 C1COc2cc(ccc2O1)c3nc(cs3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G12 compound treatment 0.338 0.0339 2.73 0.354 0.0578 5.24 5.6391 0.9539 2078553 Maybridge3_006128 COc1cc2CCN(Cc2cc1OC)C(=O)c3cc(nn3C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G13 compound treatment 0.316 0.0119 0.96 0.309 0.0127 1.16 1.4981 0.9957 2078554 Maybridge3_006129 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3cccc4nonc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G14 compound treatment 0.312 0.00794 0.64 0.312 0.0158 1.43 1.4629 0.9341 2078555 Maybridge3_006130 O=S(=O)(NCc1csc(n1)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G15 compound treatment 0.322 0.0179 1.44 0.324 0.0278 2.52 2.8025 0.9652 2078556 Maybridge3_006131 OC(=O)CC1(CC(=O)NCc2ccccc2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G16 compound treatment 0.309 0.00494 0.4 0.311 0.0147 1.34 1.2279 0.8791 2078557 Maybridge3_006132 Cc1cc(c(C)s1)S(=O)(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G17 compound treatment 0.322 0.0179 1.44 0.324 0.0278 2.52 2.8025 0.9652 2078558 Maybridge3_006133 COc1ccc(cc1NC(=O)CC2(CC(=O)O)CCCCC2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G18 compound treatment 0.324 0.0199 1.61 0.324 0.0278 2.52 2.9164 0.9763 2078559 Maybridge3_006134 Cc1nn(C)c2sc(cc12)C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G19 compound treatment 0.338 0.0339 2.73 0.326 0.0297 2.7 3.8419 1.0 2078560 Maybridge3_006135 OC(=O)CC1(CC(=O)Nc2cccc3nsnc23)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G20 compound treatment 0.32 0.0159 1.28 0.323 0.0267 2.43 2.6244 0.9556 2078561 Maybridge3_006136 O=C(NCc1csc(n1)c2cccs2)c3cccc4OCCCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G21 compound treatment 0.328 0.0239 1.93 0.327 0.0308 2.79 3.3367 0.9837 2078562 Maybridge3_006137 O=S(=O)(N1CCCCC1c2cccnc2)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G22 compound treatment 0.311 0.00694 0.56 0.31 0.0138 1.25 1.2776 0.9343 2078563 Maybridge3_006138 O=C(NCc1csc(n1)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G23 mock treatment 0.296 -0.00806 -0.65 0.297 7.5E-4 0.07 -0.4109 -0.6295 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 G24 positive control 0.094 -0.21 -16.92 0.093 -0.203 -18.45 -25.0068 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H01 compound treatment 0.335 0.0309 2.49 0.326 0.0297 2.7 3.6711 0.9992 2078564 Maybridge3_006139 O=C(NCC1CCCO1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H02 compound treatment 0.318 0.0139 1.12 0.322 0.0257 2.34 2.4464 0.9435 2078565 Maybridge3_006140 CSc1nsc(SC)c1C(=O)NC(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H03 compound treatment 0.297 -0.00706 -0.57 0.33 0.0338 3.06 1.7641 0.5662 2078566 Maybridge3_006141 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H04 compound treatment 0.318 0.0139 1.12 0.332 0.0357 3.25 3.0882 0.8994 1637765 Maybridge3_006142 Clc1ccc(cc1)C2N(CCc3sccc23)C(=O)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H05 compound treatment 0.344 0.0399 3.22 0.353 0.0568 5.15 5.9166 0.9743 2078567 Maybridge3_006143 Cc1nn(C)c2sc(cc12)C(=O)NCc3ccc(cc3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H06 compound treatment 0.334 0.0299 2.41 0.321 0.0248 2.25 3.2932 0.9994 1347672 Maybridge3_006144 O=C(Oc1ccc(cc1)c2csnn2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H07 compound treatment 0.313 0.00894 0.72 0.334 0.0377 3.43 2.9319 0.8374 2078568 Maybridge3_006145 COC(=O)c1nnn(c1O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H08 compound treatment 0.327 0.0229 1.85 0.324 0.0278 2.52 3.0872 0.9884 2078569 Maybridge3_006146 OC(=O)/C=C/C(=O)Nc1ccc(cc1)c2cnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H09 compound treatment 0.32 0.0159 1.28 0.325 0.0288 2.61 2.7528 0.9466 1676043 Maybridge3_006147 CCOC(=O)COc1cccc(NC(=O)c2ccccc2Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H10 compound treatment 0.318 0.0139 1.12 0.323 0.0267 2.43 2.5106 0.9385 2078570 Maybridge3_006148 Fc1ccc(c(F)c1)S(=O)(=O)Nc2cccc(c2)c3ncon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H11 compound treatment 0.32 0.0159 1.28 0.31 0.0138 1.25 1.79 0.9999 2078571 Maybridge3_006149 Cc1cc(SCc2ncon2)c(C)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H12 compound treatment 0.312 0.00794 0.64 0.319 0.0227 2.07 1.9122 0.8846 1605652 Maybridge3_006150 O=C(NCc1ccco1)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H13 compound treatment 0.322 0.0179 1.44 0.326 0.0297 2.7 2.9309 0.957 2078572 Maybridge3_006151 COC(=O)c1sc(cc1CS(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H14 compound treatment 0.343 0.0389 3.14 0.34 0.0437 3.97 5.0252 0.9932 1363503 Maybridge3_006152 Clc1ccc(cc1)c2ocnc2C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H15 compound treatment 0.326 0.0219 1.77 0.325 0.0288 2.61 3.0945 0.9819 1649141 Maybridge3_006153 CC(C)Oc1cccc(NC(=O)c2csnn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H16 compound treatment 0.318 0.0139 1.12 0.328 0.0318 2.88 2.8315 0.9155 1175960 Maybridge3_006154 Fc1ccc(OCCc2nc(no2)c3ccc(Cl)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H17 compound treatment 0.331 0.0269 2.17 0.349 0.0527 4.79 4.9196 0.9359 2078573 Maybridge3_006155 Clc1ccc(cc1)S(=O)(=O)Cc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H18 compound treatment 0.319 0.0149 1.2 0.33 0.0338 3.06 3.0168 0.9166 2078574 Maybridge3_006156 O=C(Nc1ccccc1)c2cccc(=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H19 compound treatment 0.317 0.0129 1.04 0.323 0.0267 2.43 2.4536 0.9286 2078575 Maybridge3_006157 CC(C)(C)C(=O)Nc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H20 compound treatment 0.353 0.0489 3.94 0.347 0.0508 4.61 6.0439 0.997 2078576 Maybridge3_006158 COc1ccc(cc1)C(=O)n2ccc(n2)c3oc(C)nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H21 compound treatment 0.33 0.0259 2.09 0.329 0.0328 2.97 3.579 0.9851 1476885 Maybridge3_006159 O=C(NCc1ccc(cc1)c2csnn2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H22 compound treatment 0.323 0.0189 1.52 0.318 0.0217 1.97 2.4743 0.9919 2078577 Maybridge3_006160 Clc1ccc(cc1)S(=O)Cc2ccsc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H23 mock treatment 0.301 -0.00306 -0.25 0.298 0.00175 0.16 -0.0621 -0.2116 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 H24 positive control 0.095 -0.209 -16.84 0.093 -0.203 -18.45 -24.9498 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I01 compound treatment 0.323 0.0189 1.52 0.324 0.0278 2.52 2.8595 0.9711 1177416 Maybridge3_006161 CCOC(=O)Cc1csc(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I02 compound treatment 0.321 0.0169 1.36 0.306 0.00975 0.89 1.5902 0.9781 2078578 Maybridge3_006162 Cc1cccc(NC(=O)c2cccc3CC(C)(C)Oc32)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I03 compound treatment 0.331 0.0269 2.17 0.33 0.0338 3.06 3.7001 0.9857 2078579 Maybridge3_006163 OC(=O)Cc1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I04 compound treatment 0.324 0.0199 1.61 0.32 0.0238 2.16 2.6597 0.9895 2078580 Maybridge3_006164 O=C(NCc1cccnc1)c2cccc3OCCCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I05 compound treatment 0.322 0.0179 1.44 0.326 0.0297 2.7 2.9309 0.957 2078581 Maybridge3_006165 CC(C)(C)OC(=O)N1CSCC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I06 compound treatment 0.321 0.0169 1.36 0.315 0.0187 1.7 2.1679 0.994 2078582 Maybridge3_006166 CN1CCN(CC1)c2ccc(CNC(=O)c3cc(F)cc4COCOc34)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I07 compound treatment 0.316 0.0119 0.96 0.32 0.0238 2.16 2.2041 0.9338 2078583 Maybridge3_006167 Cc1onc(c1CNC(=O)C2COc3ccccc3O2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I08 compound treatment 0.326 0.0219 1.77 0.32 0.0238 2.16 2.7735 0.9951 2078584 Maybridge3_006168 O=C(Nc1cccc(c1)n2cccc2)c3cccc4OCCCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I09 compound treatment 0.316 0.0119 0.96 0.305 0.00875 0.79 1.2414 0.9955 2078585 Maybridge3_006169 Cc1onc(c1CNS(=O)(=O)c2ccc3OCCc3c2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I10 compound treatment 0.322 0.0179 1.44 0.313 0.0168 1.52 2.0965 0.9997 2078586 Maybridge3_006170 CCc1ccccc1n2c(SCC(O)C(F)(F)F)nc3ccccc3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I11 compound treatment 0.33 0.0259 2.09 0.328 0.0318 2.88 3.5148 0.9875 2078587 Maybridge3_006171 CS(=O)(=O)c1ccc(cc1)c2csc(n2)c3ccc4OCCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I12 compound treatment 0.327 0.0229 1.85 0.317 0.0208 1.88 2.6379 1.0 2078588 Maybridge3_006172 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)NCc3ccc(cc3)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I13 compound treatment 0.346 0.0419 3.38 0.333 0.0367 3.34 4.7468 1.0 2078589 Maybridge3_006173 Cc1nnc(o1)c2cccc(c2)S(=O)(=O)N3CCCC3c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I14 compound treatment 0.321 0.0169 1.36 0.313 0.0168 1.52 2.0395 0.9985 2078590 Maybridge3_006174 O=S(=O)(Cc1ccccc1)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I15 compound treatment 0.319 0.0149 1.2 0.323 0.0267 2.43 2.5675 0.9475 2078591 Maybridge3_006175 O=C(Nc1ccc2nsnc2c1)c3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I16 compound treatment 0.321 0.0169 1.36 0.319 0.0227 2.07 2.4246 0.9797 2078592 Maybridge3_006176 O=S(=O)(NCCc1ccccn1)c2cccc3nsnc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I17 compound treatment 0.34 0.0359 2.89 0.323 0.0267 2.43 3.7633 0.9962 2078593 Maybridge3_006177 OC(=O)CC1(CC(=O)Nc2ccc3OCCCOc3c2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I18 compound treatment 0.35 0.0459 3.7 0.349 0.0527 4.79 6.0015 0.9919 2078594 Maybridge3_006178 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2ccc3nccnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I19 compound treatment 0.327 0.0229 1.85 0.325 0.0288 2.61 3.1514 0.9857 2078595 Maybridge3_006179 OC(=O)CC1(CC(=O)Nc2ccccc2n3cccn3)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I20 compound treatment 0.332 0.0279 2.25 0.321 0.0248 2.25 3.1794 1.0 2078596 Maybridge3_006180 O=C(NCc1csc(n1)c2cccs2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I21 compound treatment 0.336 0.0319 2.57 0.325 0.0288 2.61 3.6639 1.0 2078597 Maybridge3_006181 O=S(=O)(N1CCCCC1c2cccnc2)c3ccc4nsnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I22 compound treatment 0.314 0.00994 0.8 0.311 0.0147 1.34 1.5126 0.9697 2078598 Maybridge3_006182 Cc1ccc(cc1C)C(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I23 mock treatment 0.307 0.00294 0.24 0.297 7.5E-4 0.07 0.2154 0.8751 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 I24 positive control 0.097 -0.207 -16.67 0.093 -0.203 -18.45 -24.8359 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J01 compound treatment 0.331 0.0269 2.17 0.325 0.0288 2.61 3.3792 0.9958 2078599 Maybridge3_006183 O=C(NCc1ccsc1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J02 compound treatment 0.329 0.0249 2.01 0.32 0.0238 2.16 2.9444 0.9994 2078600 Maybridge3_006184 OC(=O)/C=C/C(=O)Nc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J03 compound treatment 0.319 0.0149 1.2 0.312 0.0158 1.43 1.8615 0.9963 2078601 Maybridge3_006185 Cc1nc(C)c(s1)S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J04 compound treatment 0.322 0.0179 1.44 0.32 0.0238 2.16 2.5458 0.981 2078602 Maybridge3_006186 c1snnc1c2ccc(cc2)c3noc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J05 compound treatment 0.329 0.0249 2.01 0.322 0.0257 2.34 3.0727 0.9971 2078603 Maybridge3_006187 Cc1nn(nc1CNC(=O)C2CCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J06 compound treatment 0.304 -6.25E-5 -0.01 0.297 7.5E-4 0.07 0.0446 0.653 1343304 Maybridge3_006188 CC(C)(C)c1ccc(OC(=O)NC(=O)c2ccc(cc2)c3csnn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J07 compound treatment 0.319 0.0149 1.2 0.315 0.0187 1.7 2.054 0.9856 2078604 Maybridge3_006189 COc1ccccc1N/C(=N\C#N)/SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J08 compound treatment 0.322 0.0179 1.44 0.309 0.0127 1.16 1.8397 0.994 2078605 Maybridge3_006190 N/C(=N\O)/COc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J09 compound treatment 0.327 0.0229 1.85 0.317 0.0208 1.88 2.6379 1.0 1183397 Maybridge3_006191 Clc1ccc2sc(nc2c1)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J10 compound treatment 0.317 0.0129 1.04 0.313 0.0168 1.52 1.8118 0.983 2078606 Maybridge3_006192 O=C(Nc1cccc(c1)c2ncon2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J11 compound treatment 0.349 0.0449 3.62 0.345 0.0488 4.43 5.6878 0.995 1349843 Maybridge3_006193 CC1CN(CC(C)O1)c2nc3c(Cl)cc(Cl)cc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J12 compound treatment 0.312 0.00794 0.64 0.314 0.0177 1.61 1.5913 0.918 2078607 Maybridge3_006194 Clc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)c3nnco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J13 compound treatment 0.316 0.0119 0.96 0.316 0.0198 1.79 1.9474 0.9573 1538087 Maybridge3_006195 CC(CC(=O)O)S(=O)(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J14 compound treatment 0.319 0.0149 1.2 0.317 0.0208 1.88 2.1824 0.9765 2078608 Maybridge3_006196 Clc1ccc(cc1)c2ocnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J15 compound treatment 0.317 0.0129 1.04 0.308 0.0118 1.07 1.4908 0.9999 2078609 Maybridge3_006197 Clc1ccc(cc1)c2noc(n2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J16 compound treatment 0.32 0.0159 1.28 0.317 0.0208 1.88 2.2393 0.9825 1335753 Maybridge3_006198 COc1ccc(cc1)C(=O)NCCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J17 compound treatment 0.337 0.0329 2.65 0.329 0.0328 2.97 3.9775 0.9984 2078610 Maybridge3_006199 Clc1ccc(OCc2ccc(cc2)c3csnn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J18 compound treatment 0.328 0.0239 1.93 0.325 0.0288 2.61 3.2083 0.9889 2078611 Maybridge3_006200 Cc1nc(C)c(o1)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J19 compound treatment 0.335 0.0309 2.49 0.336 0.0398 3.61 4.313 0.9836 2078612 Maybridge3_006201 FC(F)(F)c1ccccc1C(=O)Nc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J20 compound treatment 0.342 0.0379 3.05 0.336 0.0398 3.61 4.7115 0.9966 2078613 Maybridge3_006202 Cc1nc(C)c(o1)c2ccn(n2)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J21 compound treatment 0.324 0.0199 1.61 0.325 0.0288 2.61 2.9806 0.9728 2078614 Maybridge3_006203 Cc1noc(C)c1C(=O)NCc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J22 compound treatment 0.318 0.0139 1.12 0.32 0.0238 2.16 2.318 0.9537 1346615 Maybridge3_006204 Cc1oc(nc1c2ccccc2)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J23 mock treatment 0.302 -0.00206 -0.17 0.293 -0.00325 -0.3 -0.326 -0.9631 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 J24 positive control 0.097 -0.207 -16.67 0.094 -0.202 -18.36 -24.7717 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K01 compound treatment 0.333 0.0289 2.33 0.322 0.0257 2.34 3.3005 1.0 1882 Maybridge3_006205 c1ccc(nc1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K02 compound treatment 0.32 0.0159 1.28 0.314 0.0177 1.61 2.0468 0.9936 2078615 Maybridge3_006206 CC1(C)Cc2cccc(C(=O)NCc3ccco3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K03 compound treatment 0.32 0.0159 1.28 0.317 0.0208 1.88 2.2393 0.9825 2078616 Maybridge3_006207 CCC(=O)c1ccc(cc1)c2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K04 compound treatment 0.349 0.0449 3.62 0.337 0.0408 3.7 5.1743 0.9999 2078617 Maybridge3_006208 O=C(Nc1cc2ccccc2cn1)c3cccc4OCCCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K05 compound treatment 0.326 0.0219 1.77 0.323 0.0267 2.43 2.9661 0.9878 1668568 Maybridge3_006209 CC(C)(C)OC(=O)NC1(CC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K06 compound treatment 0.343 0.0389 3.14 0.336 0.0398 3.61 4.7685 0.9976 2078618 Maybridge3_006210 Fc1cc(C(=O)Nc2cccc(Cl)c2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K07 compound treatment 0.32 0.0159 1.28 0.323 0.0267 2.43 2.6244 0.9556 2078619 Maybridge3_006211 Cc1onc(c1CNC(=O)c2cc(F)cc3COCOc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K08 compound treatment 0.333 0.0289 2.33 0.329 0.0328 2.97 3.7498 0.9927 2078620 Maybridge3_006212 O=C(N(Cc1ccccn1)Cc2ccccn2)c3cccc4OCCCOc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K09 compound treatment 0.316 0.0119 0.96 0.317 0.0208 1.88 2.0116 0.9513 2078621 Maybridge3_006213 Cc1nc(C)c(s1)S(=O)(=O)NCc2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K10 compound treatment 0.316 0.0119 0.96 0.315 0.0187 1.7 1.8832 0.9634 2078622 Maybridge3_006214 Cc1cc(c(o1)C(F)(F)F)S(=O)(=O)NC2CCCCNC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K11 compound treatment 0.324 0.0199 1.61 0.324 0.0278 2.52 2.9164 0.9763 2078623 Maybridge3_006215 CC(=O)Nc1cc2cc(NC(=O)c3ccccc3C(F)(F)F)ccc2oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K12 compound treatment 0.329 0.0249 2.01 0.322 0.0257 2.34 3.0727 0.9971 2078624 Maybridge3_006216 O=S(=O)(NC1CCCCC1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K13 compound treatment 0.311 0.00694 0.56 0.312 0.0158 1.43 1.4059 0.916 2078625 Maybridge3_006217 FC(F)(F)c1nn(C(=O)Nc2cccc(c2)C(F)(F)F)c3ccncc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K14 compound treatment 0.315 0.0109 0.88 0.313 0.0168 1.52 1.6979 0.9663 2078626 Maybridge3_006218 O=S(=O)(NCc1csc(n1)c2cccs2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K15 compound treatment 0.328 0.0239 1.93 0.32 0.0238 2.16 2.8874 0.9984 2078627 Maybridge3_006219 OC(=O)CC1(CC(=O)NCc2csc(n2)c3cccs3)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K16 compound treatment 0.326 0.0219 1.77 0.321 0.0248 2.25 2.8377 0.9929 2078628 Maybridge3_006220 O=S(=O)(NCCc1ccccn1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K17 compound treatment 0.316 0.0119 0.96 0.317 0.0208 1.88 2.0116 0.9513 1381039 Maybridge3_006221 OC(=O)CC1(CC(=O)Nc2cc(Cl)cc(Cl)c2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K18 compound treatment 0.328 0.0239 1.93 0.323 0.0267 2.43 3.08 0.9935 2078629 Maybridge3_006222 O=C(Nc1ccc2nccnc2c1)c3ccc4nsnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K19 compound treatment 0.318 0.0139 1.12 0.306 0.00975 0.89 1.4194 0.9931 2078630 Maybridge3_006223 FC(F)(F)c1cccc(CS(=O)(=O)NCc2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K20 compound treatment 0.317 0.0129 1.04 0.317 0.0208 1.88 2.0685 0.961 2078631 Maybridge3_006224 Cc1nnsc1C(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K21 compound treatment 0.324 0.0199 1.61 0.321 0.0248 2.25 2.7238 0.9864 2078632 Maybridge3_006225 Cc1nc(cn1C)S(=O)(=O)N2CCCCC2c3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K22 compound treatment 0.314 0.00994 0.8 0.318 0.0217 1.97 1.9619 0.9209 2078633 Maybridge3_006226 Fc1ccc(C(=O)NCc2csc(n2)c3cccs3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K23 mock treatment 0.301 -0.00306 -0.25 0.293 -0.00325 -0.3 -0.383 -0.996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 K24 positive control 0.098 -0.206 -16.59 0.095 -0.201 -18.27 -24.6506 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L01 compound treatment 0.341 0.0369 2.97 0.333 0.0367 3.34 4.4621 0.9984 2078634 Maybridge3_006227 O=C(NCc1cc2ccccc2s1)c3ccc(nc3)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L02 compound treatment 0.328 0.0239 1.93 0.32 0.0238 2.16 2.8874 0.9984 1513030 Maybridge3_006228 OC(=O)CSCC(=O)Nc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L03 compound treatment 0.326 0.0219 1.77 0.324 0.0278 2.52 3.0303 0.9849 2078635 Maybridge3_006229 Cc1nc(cn1C)S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L04 compound treatment 0.341 0.0369 2.97 0.335 0.0388 3.52 4.5904 0.9965 2078636 Maybridge3_006230 Cc1csc(n1)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L05 compound treatment 0.322 0.0179 1.44 0.307 0.0107 0.98 1.7114 0.9818 2078637 Maybridge3_006231 Cc1nn(nc1CNC(=O)C2=Cc3ccccc3OC2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L06 compound treatment 0.325 0.0209 1.69 0.314 0.0177 1.61 2.3315 0.9997 2078638 Maybridge3_006232 CC(C)(C)C(=O)Oc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L07 compound treatment 0.316 0.0119 0.96 0.316 0.0198 1.79 1.9474 0.9573 2078639 Maybridge3_006233 CCOC(=O)c1c(N)onc1c2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L08 compound treatment 0.311 0.00694 0.56 0.316 0.0198 1.79 1.6627 0.8855 2078640 Maybridge3_006234 O=C(Nc1cccc(c1)c2nnco2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L09 compound treatment 0.316 0.0119 0.96 0.314 0.0177 1.61 1.819 0.9695 1540794 Maybridge3_006235 CC(C)Nc1nc2cc(Cl)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L10 compound treatment 0.323 0.0189 1.52 0.316 0.0198 1.79 2.346 0.9968 2078641 Maybridge3_006236 COC(=O)c1ccccc1Sc2nc3ccc(Cl)cc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L11 compound treatment 0.32 0.0159 1.28 0.324 0.0278 2.52 2.6886 0.9511 2078642 Maybridge3_006237 CN(C)C(=O)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L12 compound treatment 0.347 0.0429 3.46 0.336 0.0398 3.61 4.9963 0.9998 2078643 Maybridge3_006238 Clc1cccc(CNC(=O)c2ccc(cc2)c3csnn3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L13 compound treatment 0.319 0.0149 1.2 0.311 0.0147 1.34 1.7973 0.9986 1587441 Maybridge3_006239 CC(CC(=O)Nc1ccc(Cl)cc1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L14 compound treatment 0.315 0.0109 0.88 0.315 0.0187 1.7 1.8263 0.953 1559427 Maybridge3_006240 Fc1ccc(OCCC(=O)Nc2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L15 compound treatment 0.323 0.0189 1.52 0.326 0.0297 2.7 2.9878 0.9634 2078644 Maybridge3_006241 FC(F)(F)c1ccc(cc1)c2noc(n2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L16 compound treatment 0.336 0.0319 2.57 0.332 0.0357 3.25 4.1132 0.9934 1306539 Maybridge3_006242 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4c(C)noc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L17 compound treatment 0.319 0.0149 1.2 0.309 0.0127 1.16 1.6689 0.9998 2078645 Maybridge3_006243 Fc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L18 compound treatment 0.326 0.0219 1.77 0.32 0.0238 2.16 2.7735 0.9951 2078646 Maybridge3_006244 CCOC(=O)c1ncoc1c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L19 compound treatment 0.326 0.0219 1.77 0.327 0.0308 2.79 3.2228 0.9756 1146607 Maybridge3_006245 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L20 compound treatment 0.319 0.0149 1.2 0.311 0.0147 1.34 1.7973 0.9986 1395750 Maybridge3_006246 CC(C)(C)NCC(O)COc1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L21 compound treatment 0.34 0.0359 2.89 0.332 0.0357 3.25 4.3409 0.9984 1440906 Maybridge3_006247 Fc1ccc(cc1Cl)S(=O)(=O)NCc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L22 compound treatment 0.339 0.0349 2.81 0.336 0.0398 3.61 4.5407 0.9924 2078647 Maybridge3_006248 O/N=C/C1=C(Cl)c2cc(Cl)ccc2SC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L23 mock treatment 0.304 -6.25E-5 -0.01 0.296 -2.5E-4 -0.02 -0.0196 -0.8434 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 L24 positive control 0.097 -0.207 -16.67 0.094 -0.202 -18.36 -24.7717 -0.9988 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M01 compound treatment 0.325 0.0209 1.69 0.323 0.0267 2.43 2.9091 0.9841 1112350 Maybridge3_006249 c1cc(ccn1)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M02 compound treatment 0.315 0.0109 0.88 0.304 0.00775 0.7 1.1202 0.9938 2078648 Maybridge3_006250 CC1(C)Cc2cccc(C(=O)NCC3COc4ccccc4O3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M03 compound treatment 0.316 0.0119 0.96 0.313 0.0168 1.52 1.7548 0.9755 1037012 Maybridge3_006251 OCCN(CCO)c1cccc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M04 compound treatment 0.321 0.0169 1.36 0.322 0.0257 2.34 2.6172 0.9671 2078649 Maybridge3_006252 Cn1cccc1CNC(=O)c2cc(F)cc3COCOc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M05 compound treatment 0.328 0.0239 1.93 0.321 0.0248 2.25 2.9516 0.9971 1166531 Maybridge3_006253 OC(=O)C1(CC1)NC(=O)OCC2c3ccccc3-c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M06 compound treatment 0.321 0.0169 1.36 0.31 0.0138 1.25 1.847 0.999 2078650 Maybridge3_006254 Fc1cc(C(=O)NC2CCCCC2)c3OCOCc3c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M07 compound treatment 0.316 0.0119 0.96 0.317 0.0208 1.88 2.0116 0.9513 2078651 Maybridge3_006255 Cc1onc(c1CNC(=O)c2ccco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M08 compound treatment 0.321 0.0169 1.36 0.313 0.0168 1.52 2.0395 0.9985 2078652 Maybridge3_006256 FC(F)(Sc1ccccc1)C(=O)c2cnc3ccccn23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M09 compound treatment 0.32 0.0159 1.28 0.319 0.0227 2.07 2.3677 0.9738 2078653 Maybridge3_006257 CC(=O)N1CCC(CC1)C(=O)NCc2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M10 compound treatment 0.49 0.186 14.97 0.485 0.189 17.13 22.7024 0.9977 2078654 Maybridge3_006258 CN1CCOc2cc(/C=C/3\C(=O)Nc4ccccc34)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M11 compound treatment 0.32 0.0159 1.28 0.312 0.0158 1.43 1.9184 0.9986 2078655 Maybridge3_006259 COc1ccccc1Nc2snc3[nH]c(cc23)C(=O)c4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M12 compound treatment 0.32 0.0159 1.28 0.313 0.0168 1.52 1.9826 0.9964 2078656 Maybridge3_006260 O=S(=O)(NCc1ccsc1)c2ccc(nc2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M13 compound treatment 0.322 0.0179 1.44 0.316 0.0198 1.79 2.289 0.9943 2078657 Maybridge3_006261 FC(F)(F)c1nn(C(=O)Nc2ccc(Cl)cc2)c3ccncc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M14 compound treatment 0.319 0.0149 1.2 0.318 0.0217 1.97 2.2466 0.9718 2078658 Maybridge3_006262 Cn1cnc(c1)S(=O)(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M15 compound treatment 0.318 0.0139 1.12 0.312 0.0158 1.43 1.8045 0.9928 2078659 Maybridge3_006263 OC(=O)CC1(CC(=O)NCC2COc3ccccc3O2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M16 compound treatment 0.311 0.00694 0.56 0.31 0.0138 1.25 1.2776 0.9343 2078660 Maybridge3_006264 O=S(=O)(NCCc1ccccn1)c2cc(cs2)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M17 compound treatment 0.323 0.0189 1.52 0.325 0.0288 2.61 2.9236 0.9673 2078661 Maybridge3_006265 OC(=O)CC1(CC(=O)Nc2ccc3ccccc3n2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M18 compound treatment 0.356 0.0519 4.18 0.359 0.0628 5.7 6.985 0.9885 2078662 Maybridge3_006266 Clc1ccc(Oc2ncccc2C(=O)Nc3ccc4nccnc4c3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M19 compound treatment 0.34 0.0359 2.89 0.344 0.0478 4.33 5.1111 0.9807 2078663 Maybridge3_006267 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)c4ccno4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M20 compound treatment 0.324 0.0199 1.61 0.315 0.0187 1.7 2.3387 0.9996 2078664 Maybridge3_006268 O=C(NCc1csc(n1)c2cccs2)c3ccc4nsnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M21 compound treatment 0.313 0.00894 0.72 0.314 0.0177 1.61 1.6482 0.934 2078665 Maybridge3_006269 CSc1c(c(N)nn1C(=O)C2CC2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M22 compound treatment 0.319 0.0149 1.2 0.311 0.0147 1.34 1.7973 0.9986 2078666 Maybridge3_006270 O=C1NC2(CCN(CC2)S(=O)(=O)c3cccs3)Oc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M23 mock treatment 0.303 -0.00106 -0.09 0.298 0.00175 0.16 0.0518 0.2872 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 M24 positive control 0.098 -0.206 -16.59 0.096 -0.2 -18.18 -24.5864 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N01 compound treatment 0.339 0.0349 2.81 0.336 0.0398 3.61 4.5407 0.9924 2078667 Maybridge3_006271 O=C(NCc1ccc(s1)c2cccs2)c3ccc(nc3)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N02 compound treatment 0.324 0.0199 1.61 0.318 0.0217 1.97 2.5313 0.9947 2078668 Maybridge3_006272 Nc1cccc(c1)c2cnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N03 compound treatment 0.319 0.0149 1.2 0.312 0.0158 1.43 1.8615 0.9963 2078669 Maybridge3_006273 Cc1noc(C)c1S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N04 compound treatment 0.321 0.0169 1.36 0.32 0.0238 2.16 2.4888 0.9756 2078670 Maybridge3_006274 CC(C)(C)c1csc(n1)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N05 compound treatment 0.32 0.0159 1.28 0.314 0.0177 1.61 2.0468 0.9936 2078671 Maybridge3_006275 Cc1nn(nc1CNS(=O)(=O)c2cccs2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N06 compound treatment 0.32 0.0159 1.28 0.321 0.0248 2.25 2.4961 0.9647 2078672 Maybridge3_006276 O=C(Oc1ccc(cc1)c2csnn2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N07 compound treatment 0.325 0.0209 1.69 0.327 0.0308 2.79 3.1659 0.9709 1120951 Maybridge3_006277 CCOC(=O)c1c(NC(=O)C)nc(SC)n1Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N08 compound treatment 0.319 0.0149 1.2 0.324 0.0278 2.52 2.6317 0.9428 1254965 Maybridge3_006278 CC(=O)Nc1cccc(c1)c2nnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N09 compound treatment 0.366 0.0619 4.99 0.368 0.0717 6.51 8.1321 0.9913 1562802 Maybridge3_006279 CSc1nsc(SC)c1C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N10 compound treatment 0.327 0.0229 1.85 0.323 0.0267 2.43 3.023 0.9909 2078673 Maybridge3_006280 CC(C)S(=O)(=O)c1nnn(c1N)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N11 compound treatment 0.317 0.0129 1.04 0.32 0.0238 2.16 2.2611 0.9443 1533469 Maybridge3_006281 CN(C)C(=O)Oc1cccc(NC(=O)c2cc(Cl)cc(Cl)c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N12 compound treatment 0.325 0.0209 1.69 0.314 0.0177 1.61 2.3315 0.9997 2078674 Maybridge3_006282 Fc1cccc(Cl)c1/C=N/c2cccc(c2)c3ncon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N13 compound treatment 0.321 0.0169 1.36 0.315 0.0187 1.7 2.1679 0.994 2078675 Maybridge3_006283 CC(CC(=O)Oc1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N14 compound treatment 0.333 0.0289 2.33 0.33 0.0338 3.06 3.814 0.9909 1426127 Maybridge3_006284 COc1cc(NC(=O)CCOc2ccc(F)cc2)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N15 compound treatment 0.318 0.0139 1.12 0.314 0.0177 1.61 1.9329 0.9844 2078676 Maybridge3_006285 FC(F)(F)c1ccc(cc1)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N16 compound treatment 0.335 0.0309 2.49 0.329 0.0328 2.97 3.8637 0.9961 1127085 Maybridge3_006286 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N17 compound treatment 0.322 0.0179 1.44 0.313 0.0168 1.52 2.0965 0.9997 2078677 Maybridge3_006287 N/C(=N\O)/CCS(=O)(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N18 compound treatment 0.325 0.0209 1.69 0.317 0.0208 1.88 2.524 0.9985 2078678 Maybridge3_006288 Cc1cc(oc(=O)c1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N19 compound treatment 0.326 0.0219 1.77 0.324 0.0278 2.52 3.0303 0.9849 1360738 Maybridge3_006289 CSc1nsc(SC)c1C(=O)Nc2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N20 compound treatment 0.32 0.0159 1.28 0.318 0.0217 1.97 2.3035 0.9782 2078679 Maybridge3_006290 O=C(NC(=O)c1cccc(=O)o1)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N21 compound treatment 0.327 0.0229 1.85 0.319 0.0227 2.07 2.7663 0.9985 2078680 Maybridge3_006291 CC(C)(C)S(=O)(=O)/C(=C/c1ccc(F)c(Cl)c1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N22 compound treatment 0.328 0.0239 1.93 0.326 0.0297 2.7 3.2725 0.9863 2078681 Maybridge3_006292 Cc1ccc(C)n1c2ccc(/C=C(/C#N)\S(=O)(=O)C(C)(C)C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N23 mock treatment 0.31 0.00594 0.48 0.298 0.00175 0.16 0.4504 0.894 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 N24 positive control 0.098 -0.206 -16.59 0.096 -0.2 -18.18 -24.5864 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O01 compound treatment 0.341 0.0369 2.97 0.332 0.0357 3.25 4.3979 0.9991 2078682 Maybridge3_006293 NC(=O)c1cnn2c(ccnc12)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O02 compound treatment 0.326 0.0219 1.77 0.32 0.0238 2.16 2.7735 0.9951 2078683 Maybridge3_006294 CC1(C)Cc2cccc(C(=O)NCc3cccs3)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O03 compound treatment 0.322 0.0179 1.44 0.318 0.0217 1.97 2.4174 0.9882 1020957 Maybridge3_006295 C1CCC(CC1)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O04 compound treatment 0.33 0.0259 2.09 0.322 0.0257 2.34 3.1297 0.9984 2078684 Maybridge3_006296 Cc1cc(CNC(=O)c2cc(F)cc3COCOc23)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O05 compound treatment 0.367 0.0629 5.07 0.36 0.0638 5.79 7.6755 0.9978 2078685 Maybridge3_006297 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3ccccc3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O06 compound treatment 0.331 0.0269 2.17 0.327 0.0308 2.79 3.5075 0.9922 2078686 Maybridge3_006298 COc1ccc(NC(=O)c2cc(F)cc3COCOc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O07 compound treatment 0.325 0.0209 1.69 0.326 0.0297 2.7 3.1017 0.9743 2078687 Maybridge3_006299 Cc1onc(c1CNC(=O)c2cnn(c2C)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O08 compound treatment 0.329 0.0249 2.01 0.319 0.0227 2.07 2.8802 0.9999 2078688 Maybridge3_006300 Cn1ccnc1SC(F)(F)C(=O)c2cnc3ccccn23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O09 compound treatment 0.356 0.0519 4.18 0.359 0.0628 5.7 6.985 0.9885 1113582 Maybridge3_006301 COc1ccc(cc1)c2onc3ccc(Br)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O10 compound treatment 0.342 0.0379 3.05 0.333 0.0367 3.34 4.519 0.999 2078689 Maybridge3_006302 CC(C)(C)C(=O)Nc1ncccc1/C=C/2\C(=O)Nc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O11 compound treatment 0.316 0.0119 0.96 0.311 0.0147 1.34 1.6265 0.9868 2078690 Maybridge3_006303 COC(=O)c1c(C)csc1NC(=O)CSCc2c(F)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O12 compound treatment 0.341 0.0369 2.97 0.34 0.0437 3.97 4.9113 0.9899 2078691 Maybridge3_006304 O=S(=O)(NCc1ccc(s1)c2cccs2)c3ccc(nc3)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O13 compound treatment 0.32 0.0159 1.28 0.319 0.0227 2.07 2.3677 0.9738 2078692 Maybridge3_006305 FC(F)(F)c1nn(c2ccncc12)S(=O)(=O)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O14 compound treatment 0.32 0.0159 1.28 0.321 0.0248 2.25 2.4961 0.9647 2078693 Maybridge3_006306 O=S(=O)(NCc1csc(n1)c2cccs2)c3cccc4cccnc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O15 compound treatment 0.329 0.0249 2.01 0.321 0.0248 2.25 3.0085 0.9984 2078694 Maybridge3_006307 OC(=O)CC1(CC(=O)NCc2cc(F)cc3COCOc23)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O16 compound treatment 0.323 0.0189 1.52 0.317 0.0208 1.88 2.4102 0.9945 2078695 Maybridge3_006308 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O17 compound treatment 0.329 0.0249 2.01 0.328 0.0318 2.88 3.4578 0.9844 2078696 Maybridge3_006309 OC(=O)CC1(CC(=O)Nc2ccc3sccc3c2)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O18 compound treatment 0.328 0.0239 1.93 0.321 0.0248 2.25 2.9516 0.9971 2078697 Maybridge3_006310 O=C(NCc1csc(n1)c2cccs2)C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O19 compound treatment 0.352 0.0479 3.86 0.351 0.0548 4.97 6.2437 0.9922 2078698 Maybridge3_006311 OC(=O)CSCC(=O)Nc1ccc(cc1)c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O20 compound treatment 0.329 0.0249 2.01 0.318 0.0217 1.97 2.816 1.0 2078699 Maybridge3_006312 Cc1cc(no1)C(=O)NCc2csc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O21 compound treatment 0.332 0.0279 2.25 0.324 0.0278 2.52 3.3719 0.9984 2078700 Maybridge3_006313 CSc1c(c(N)nn1C(=O)c2cccs2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O22 compound treatment 0.346 0.0419 3.38 0.35 0.0537 4.88 5.8379 0.9839 2078701 Maybridge3_006314 Nc1cc(nn1S(=O)(=O)c2ccc(F)c(F)c2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O23 mock treatment 0.321 0.0169 1.36 0.3 0.00375 0.34 1.2051 0.8573 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 O24 positive control 0.098 -0.206 -16.59 0.096 -0.2 -18.18 -24.5864 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P01 compound treatment 0.324 0.0199 1.61 0.324 0.0278 2.52 2.9164 0.9763 2078702 Maybridge3_006315 O=C(NCC1CCNCC1)c2ccno2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P02 compound treatment 0.326 0.0219 1.77 0.322 0.0257 2.34 2.9019 0.9905 2078703 Maybridge3_006316 Clc1ccc(/C=N/c2ccc(cc2)c3csnn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P03 compound treatment 0.318 0.0139 1.12 0.321 0.0248 2.25 2.3822 0.9486 2078704 Maybridge3_006317 Cc1cc(c(C)s1)S(=O)(=O)NCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P04 compound treatment 0.326 0.0219 1.77 0.322 0.0257 2.34 2.9019 0.9905 2078705 Maybridge3_006318 c1snnc1c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P05 compound treatment 0.321 0.0169 1.36 0.311 0.0147 1.34 1.9112 1.0 2078706 Maybridge3_006319 Cc1nn(nc1CNS(=O)(=O)c2cccc3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P06 compound treatment 0.344 0.0399 3.22 0.337 0.0408 3.7 4.8896 0.9976 2078707 Maybridge3_006320 NC(=O)c1ccc(s1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P07 compound treatment 0.318 0.0139 1.12 0.322 0.0257 2.34 2.4464 0.9435 1523106 Maybridge3_006321 CCOC(=O)c1c(N)nc(SC)n1Cc2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P08 compound treatment 0.323 0.0189 1.52 0.323 0.0267 2.43 2.7953 0.9749 1607915 Maybridge3_006322 CC(C)(C)C(=O)Nc1cccc(c1)c2nnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P09 compound treatment 0.322 0.0179 1.44 0.319 0.0227 2.07 2.4816 0.9847 2078708 Maybridge3_006323 CSc1nsc(SC)c1C(=O)NC(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P10 compound treatment 0.33 0.0259 2.09 0.322 0.0257 2.34 3.1297 0.9984 2078709 Maybridge3_006324 FC(F)(F)c1ccc(c(Cl)c1)S(=O)(=O)Nc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P11 compound treatment 0.321 0.0169 1.36 0.314 0.0177 1.61 2.1037 0.9966 1527207 Maybridge3_006325 CN(C)C(=O)Oc1cccc(NC(=O)c2c(F)cccc2F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P12 compound treatment 0.32 0.0159 1.28 0.315 0.0187 1.7 2.111 0.9903 2078710 Maybridge3_006326 N#Cc1ccc(/C=N/c2cccc(c2)c3ncon3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P13 compound treatment 0.318 0.0139 1.12 0.314 0.0177 1.61 1.9329 0.9844 1258268 Maybridge3_006327 CC(CC(=O)Oc1ccc(C#N)cc1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P14 compound treatment 0.326 0.0219 1.77 0.325 0.0288 2.61 3.0945 0.9819 2078711 Maybridge3_006328 CC1=C(SCCO1)C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P15 compound treatment 0.318 0.0139 1.12 0.317 0.0208 1.88 2.1255 0.9694 2078712 Maybridge3_006329 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2csnn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P16 compound treatment 0.325 0.0209 1.69 0.319 0.0227 2.07 2.6524 0.9949 1614756 Maybridge3_006330 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P17 compound treatment 0.34 0.0359 2.89 0.333 0.0367 3.34 4.4051 0.9975 1410339 Maybridge3_006331 O=C(Nc1ccc(cc1)c2cnco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P18 compound treatment 0.328 0.0239 1.93 0.334 0.0377 3.43 3.786 0.963 2078713 Maybridge3_006332 Cc1nc(C)c(o1)c2ccn(n2)C(=O)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P19 compound treatment 0.36 0.0559 4.5 0.348 0.0517 4.7 6.5067 0.9998 1546222 Maybridge3_006333 O=C(Nc1ccc(cc1)c2csnn2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P20 compound treatment 0.323 0.0189 1.52 0.321 0.0248 2.25 2.6669 0.9822 2078714 Maybridge3_006334 Cc1nc(C)c(o1)c2ccnc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P21 compound treatment 0.322 0.0179 1.44 0.321 0.0248 2.25 2.61 0.9772 2078715 Maybridge3_006335 O/N=C/c1ccc(F)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P22 compound treatment 0.317 0.0129 1.04 0.313 0.0168 1.52 1.8118 0.983 2078716 Maybridge3_006336 CS(=O)(=O)/C(=C/c1ccsc1\C=C(/C#N)\S(=O)(=O)C)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P23 mock treatment 0.315 0.0109 0.88 0.305 0.00875 0.79 1.1844 0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1448 P24 positive control 0.1 -0.204 -16.43 0.099 -0.197 -17.9 -24.28 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A01 compound treatment 0.311 0.00506 0.41 0.311 0.00107 0.1 0.3567 0.8514 2078717 Maybridge3_006337 COC(=O)c1sc-2c(CSc3ccc(Cl)cc23)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A02 compound treatment 0.332 0.0261 2.1 0.336 0.0261 2.37 3.1571 0.9982 2078718 Maybridge3_006338 NC(=O)c1sc(C#N)c(c2ccco2)c1c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A03 compound treatment 0.299 -0.00694 -0.56 0.302 -0.00793 -0.72 -0.9042 -0.9921 2078719 Maybridge3_006339 FC(F)(F)c1cccc(NC(=O)CCSc2cccs2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A04 compound treatment 0.308 0.00206 0.17 0.307 -0.00293 -0.27 -0.0708 -0.2257 2078720 Maybridge3_006340 CCN(CC)C(=O)c1ccc(s1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A05 compound treatment 0.305 -9.37E-4 -0.08 0.314 0.00407 0.37 0.2076 0.5511 2078721 Maybridge3_006341 CC(=O)n1cc(c(C)n1)c2nsc(Nc3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A06 compound treatment 0.304 -0.00194 -0.16 0.307 -0.00293 -0.27 -0.2986 -0.9676 1286044 Maybridge3_006342 CC(=O)Nc1ccccc1OCC(O)CS(=O)(=O)Cc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A07 compound treatment 0.314 0.00806 0.65 0.311 0.00107 0.1 0.5275 0.8037 2078722 Maybridge3_006343 Clc1ccc(OCc2noc(n2)c3ccsc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A08 compound treatment 0.299 -0.00694 -0.56 0.3 -0.00993 -0.9 -1.0326 -0.9735 1598417 Maybridge3_006344 CCOC(=O)CCc1c([nH]c2ccccc12)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A09 compound treatment 0.305 -9.37E-4 -0.08 0.3 -0.00993 -0.9 -0.691 -0.7636 1184219 Maybridge3_006345 NC(=O)c1ncoc1c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A10 compound treatment 0.303 -0.00294 -0.24 0.304 -0.00593 -0.54 -0.5481 -0.9318 2078723 Maybridge3_006346 N/C(=N\O)/c1cccc(c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A11 compound treatment 0.305 -9.37E-4 -0.08 0.305 -0.00493 -0.45 -0.37 -0.8148 2078724 Maybridge3_006347 Clc1cc(/C=N/c2cccnc2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A12 compound treatment 0.328 0.0221 1.78 0.331 0.0211 1.91 2.6084 0.9993 2078725 Maybridge3_006348 CN(c1ccccc1)c2nc(nc(C)c2Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A13 compound treatment 0.312 0.00606 0.49 0.311 0.00107 0.1 0.4137 0.8312 2078726 Maybridge3_006349 O=C(N1CCOCC1)/C(=C\c2cccs2)/c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A14 compound treatment 0.281 -0.0249 -2.01 0.288 -0.0219 -1.99 -2.8278 -1.0 1656669 Maybridge3_006350 CC(O)(CNCc1ccc(Cl)cc1)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A15 compound treatment 0.301 -0.00494 -0.4 0.301 -0.00893 -0.81 -0.8545 -0.9462 2078727 Maybridge3_006351 c1csc(c1)c2ccc(s2)c3ccon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A16 compound treatment 0.296 -0.00994 -0.8 0.301 -0.00893 -0.81 -1.1392 -1.0 2078728 Maybridge3_006352 CCOC(=O)n1nccc1c2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A17 compound treatment 0.311 0.00506 0.41 0.313 0.00307 0.28 0.4851 0.9827 2078729 Maybridge3_006353 O=S(=O)(N1CCCC1)c2ccc(s2)c3ccc(s3)S(=O)(=O)N4CCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A18 compound treatment 0.306 6.25E-5 0.01 0.31 6.67E-5 0.01 0.0078 0.9958 2078730 Maybridge3_006354 CC(C)Oc1cccc(NC(=O)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A19 compound treatment 0.306 6.25E-5 0.01 0.309 -9.33E-4 -0.08 -0.0563 -0.6639 1604359 Maybridge3_006355 COc1ccc(NC(=O)c2c(C)oc3c(F)c(F)c(F)c(F)c23)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A20 compound treatment 0.33 0.0241 1.94 0.33 0.0201 1.82 2.6581 0.9995 2078731 Maybridge3_006356 COC(=O)c1sc(c(c1S(=O)(=O)N(C)C)c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A21 compound treatment 0.305 -9.37E-4 -0.08 0.307 -0.00293 -0.27 -0.2417 -0.8732 2078732 Maybridge3_006357 CCOC(=O)c1noc(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A22 compound treatment 0.306 6.25E-5 0.01 0.309 -9.33E-4 -0.08 -0.0563 -0.6639 2078733 Maybridge3_006358 Cc1nnsc1c2nc(cs2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A23 mock treatment 0.294 -0.0119 -0.96 0.348 0.0381 3.46 1.7636 0.4917 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 A24 positive control 0.087 -0.219 -17.63 0.089 -0.221 -20.05 -26.6471 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B01 compound treatment 0.321 0.0151 1.21 0.328 0.0181 1.64 2.0173 0.989 2078734 Maybridge3_006359 CC(C)(C)C(=O)Nc1cccc(c1C(=O)O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B02 compound treatment 0.334 0.0281 2.26 0.335 0.0251 2.28 3.2068 1.0 1363801 Maybridge3_006360 COc1ccc2cc(ccc2c1)c3ccon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B03 compound treatment 0.316 0.0101 0.81 0.328 0.0181 1.64 1.7326 0.9472 2078735 Maybridge3_006361 CSc1c(NC(=O)/C=C/C(=O)O)cccc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B04 compound treatment 0.319 0.0131 1.05 0.322 0.0121 1.1 1.5183 0.9998 2078736 Maybridge3_006362 S=C(SCc1ncon1)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B05 compound treatment 0.326 0.0201 1.62 0.325 0.0151 1.37 2.1094 0.9966 2078737 Maybridge3_006363 Nc1c(Cl)cc(cc1Cl)c2noc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B06 compound treatment 0.312 0.00606 0.49 0.317 0.00707 0.64 0.7988 0.9909 1044815 Maybridge3_006364 O=C(c1ccc[nH]1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B07 compound treatment 0.314 0.00806 0.65 0.318 0.00807 0.73 0.9768 0.9982 2078738 Maybridge3_006365 COC(OC)(C(C#N)c1ccccc1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B08 compound treatment 0.317 0.0111 0.89 0.326 0.0161 1.46 1.6611 0.972 2078739 Maybridge3_006366 Cn1nc(c(c1/N=C/c2ccc[nH]2)c3ccccc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B09 compound treatment 0.324 0.0181 1.45 0.329 0.0191 1.73 2.2523 0.9963 2078740 Maybridge3_006367 CCOC(=O)Cc1csc(n1)c2ncc(cc2OCC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B10 compound treatment 0.319 0.0131 1.05 0.322 0.0121 1.1 1.5183 0.9998 1144915 Maybridge3_006368 Fc1ccc(COc2ccc(cc2)c3nnco3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B11 compound treatment 0.325 0.0191 1.54 0.327 0.0171 1.55 2.1809 1.0 2078741 Maybridge3_006369 CC(C)(C)CC(=O)N1CCN(CC1)c2cc(ccn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B12 compound treatment 0.313 0.00706 0.57 0.315 0.00507 0.46 0.7273 0.9945 2078742 Maybridge3_006370 COc1ccc(C/N=C/c2ccc(OC)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B13 compound treatment 0.333 0.0271 2.18 0.339 0.0291 2.64 3.4066 0.9955 2078743 Maybridge3_006371 COc1cc(CCc2nnc(o2)c3cccs3)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B14 compound treatment 0.325 0.0191 1.54 0.33 0.0201 1.82 2.3734 0.9964 1177562 Maybridge3_006372 O=C(CC1(CC2CC3CC(C2)C1)C3)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B15 compound treatment 0.316 0.0101 0.81 0.319 0.00907 0.82 1.1549 1.0 2078744 Maybridge3_006373 O/N=C/c1cc(Br)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B16 compound treatment 0.314 0.00806 0.65 0.316 0.00607 0.55 0.8485 0.9966 2078745 Maybridge3_006374 COC(=O)c1ccc(cc1)c2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B17 compound treatment 0.334 0.0281 2.26 0.343 0.0331 3.0 3.7203 0.9902 1358213 Maybridge3_006375 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B18 compound treatment 0.317 0.0111 0.89 0.321 0.0111 1.0 1.3402 0.9982 2078746 Maybridge3_006376 CCc1sc(nc1C(=O)OC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B19 compound treatment 0.327 0.0211 1.7 0.334 0.0241 2.18 2.744 0.9922 1450817 Maybridge3_006377 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B20 compound treatment 0.325 0.0191 1.54 0.328 0.0181 1.64 2.245 0.9995 1460503 Maybridge3_006378 COc1cc(NC(=O)OC(C)(C)C)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B21 compound treatment 0.323 0.0171 1.37 0.326 0.0161 1.46 2.0028 0.9996 2078747 Maybridge3_006379 Cc1noc(C)c1C(=O)OCc2ccc(o2)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B22 compound treatment 0.316 0.0101 0.81 0.321 0.0111 1.0 1.2833 0.9943 2078748 Maybridge3_006380 N#Cc1ccc(Sc2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B23 mock treatment 0.308 0.00206 0.17 0.316 0.00607 0.55 0.5068 0.8812 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 B24 positive control 0.089 -0.217 -17.47 0.089 -0.221 -20.05 -26.5332 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C01 compound treatment 0.309 0.00306 0.25 0.313 0.00307 0.28 0.3712 0.9982 2078749 Maybridge3_006381 Clc1ccc(SCc2noc(n2)c3ccsc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C02 compound treatment 0.321 0.0151 1.21 0.325 0.0151 1.37 1.8247 0.9982 2078750 Maybridge3_006382 c1cc(no1)c2ccc(s2)c3noc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C03 compound treatment 0.34 0.0341 2.74 0.34 0.0301 2.73 3.8694 1.0 2078751 Maybridge3_006383 NC(=O)c1cc2CSc3ccc(Cl)cc3-c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C04 compound treatment 0.312 0.00606 0.49 0.322 0.0121 1.1 1.1197 0.9337 1087730 Maybridge3_006384 C(c1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C05 compound treatment 0.392 0.0861 6.93 0.382 0.0721 6.54 9.5261 0.9996 2078752 Maybridge3_006385 COC(=O)c1sccc1c2ccc(/C=C(\C#N)/S(=O)(=O)C)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C06 compound treatment 0.317 0.0111 0.89 0.319 0.00907 0.82 1.2119 0.9992 2078753 Maybridge3_006386 COC(=O)c1sccc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C07 compound treatment 0.31 0.00406 0.33 0.315 0.00507 0.46 0.5565 0.9861 2078754 Maybridge3_006387 FC(F)(F)c1ccc(cc1)c2ocnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C08 compound treatment 0.314 0.00806 0.65 0.318 0.00807 0.73 0.9768 0.9982 2078755 Maybridge3_006388 FC(F)(F)c1n[nH]cc1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C09 compound treatment 0.307 0.00106 0.09 0.319 0.00907 0.82 0.6424 0.7764 2078756 Maybridge3_006389 NC(=O)c1ncoc1c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C10 compound treatment 0.311 0.00506 0.41 0.318 0.00807 0.73 0.806 0.9618 2078757 Maybridge3_006390 CSc1cc(nn1C(=O)C)c2nccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C11 compound treatment 0.307 0.00106 0.09 0.315 0.00507 0.46 0.3857 0.8245 2078758 Maybridge3_006391 Clc1ccc(/C=C/C#N)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C12 compound treatment 0.327 0.0211 1.7 0.337 0.0271 2.46 2.9366 0.9836 1417919 Maybridge3_006392 COC(=O)c1cc(=O)n2c3ccccc3sc2c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C13 compound treatment 0.267 -0.0389 -3.14 0.324 0.0141 1.28 -1.3143 -0.3882 2078759 Maybridge3_006393 CS(=O)(=O)/C(=C/c1ccc(s1)c2cccs2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C14 compound treatment 0.318 0.0121 0.97 0.32 0.0101 0.91 1.333 0.9995 2078760 Maybridge3_006394 Cc1noc(c1c2nc(no2)c3cccc(c3)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C15 compound treatment 0.323 0.0171 1.37 0.345 0.0351 3.18 3.2223 0.9294 2078761 Maybridge3_006395 CNC(=O)n1nccc1c2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C16 compound treatment 0.324 0.0181 1.45 0.325 0.0151 1.37 1.9955 0.9995 2078762 Maybridge3_006396 COc1ccc(/C=C(/CC(=O)O)\C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C17 compound treatment 0.318 0.0121 0.97 0.32 0.0101 0.91 1.333 0.9995 1644058 Maybridge3_006397 CCN(CC)S(=O)(=O)c1ccc(s1)c2ccc(s2)S(=O)(=O)N(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C18 compound treatment 0.312 0.00606 0.49 0.318 0.00807 0.73 0.863 0.9806 2078763 Maybridge3_006398 C/C(=N\O)/c1ccc(Sc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C19 compound treatment 0.318 0.0121 0.97 0.322 0.0121 1.1 1.4613 0.9982 1241579 Maybridge3_006399 Cc1oc2c(F)c(F)c(F)c(F)c2c1C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C20 compound treatment 0.371 0.0651 5.24 0.383 0.0731 6.63 8.3945 0.9932 2078764 Maybridge3_006400 Cc1cc(/C=C(\C#N)/S(=O)(=O)C)c(C)n1c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C21 compound treatment 0.315 0.00906 0.73 0.315 0.00507 0.46 0.8412 0.9752 2078765 Maybridge3_006401 CC(=O)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C22 compound treatment 0.318 0.0121 0.97 0.317 0.00707 0.64 1.1404 0.9797 2078766 Maybridge3_006402 CN(NS(=O)(=O)c1ccccc1C(F)(F)F)c2cnc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C23 mock treatment 0.298 -0.00794 -0.64 0.301 -0.00893 -0.81 -1.0254 -0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 C24 positive control 0.092 -0.214 -17.23 0.093 -0.217 -19.69 -26.1057 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D01 compound treatment 0.328 0.0221 1.78 0.336 0.0261 2.37 2.9293 0.99 2078767 Maybridge3_006403 CSc1ccc(/C=N/c2ccc(Cl)cc2Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D02 compound treatment 0.178 -0.128 -10.3 0.195 -0.115 -10.43 -14.6619 -1.0 2078768 Maybridge3_006404 FC(F)(F)c1cc(n(n1)c2ccc(cc2)N3C(=O)C=CC3=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D03 compound treatment 0.317 0.0111 0.89 0.325 0.0151 1.37 1.597 0.9784 2078769 Maybridge3_006405 Clc1ccc(cc1)S(=O)(=O)Cc2nc(no2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D04 compound treatment 0.321 0.0151 1.21 0.324 0.0141 1.28 1.7605 0.9997 1006808 Maybridge3_006406 COc1cc2CC(=O)Nc2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D05 compound treatment 0.316 0.0101 0.81 0.319 0.00907 0.82 1.1549 1.0 2078770 Maybridge3_006407 Cc1cc(NC(=O)COC(Cc2ccccc2)C(F)(F)F)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D06 compound treatment 0.317 0.0111 0.89 0.327 0.0171 1.55 1.7253 0.9655 1683662 Maybridge3_006408 Cc1nc(sc1C(=O)Nc2ccccc2)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D07 compound treatment 0.341 0.0351 2.82 0.346 0.0361 3.27 4.3114 0.9973 2078771 Maybridge3_006409 OC(=O)c1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D08 compound treatment 0.331 0.0251 2.02 0.328 0.0181 1.64 2.5867 0.9947 2078772 Maybridge3_006410 Cn1nc(c(c1NC(=O)CSCC(=O)O)c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D09 compound treatment 0.331 0.0251 2.02 0.331 0.0211 1.91 2.7792 0.9996 1275278 Maybridge3_006411 Cc1ccc(cc1)S(=O)(=O)Cc2csc(n2)N3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D10 compound treatment 0.318 0.0121 0.97 0.324 0.0141 1.28 1.5897 0.9909 1056522 Maybridge3_006412 OC(c1ccccc1)c2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D11 compound treatment 0.324 0.0181 1.45 0.329 0.0191 1.73 2.2523 0.9963 2078773 Maybridge3_006413 CCS(=O)(=O)N1CCN(CC1)c2cc(ccn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D12 compound treatment 0.315 0.00906 0.73 0.315 0.00507 0.46 0.8412 0.9752 1558506 Maybridge3_006414 COc1ccc(CNCc2ccc(OC)c(OC)c2)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D13 compound treatment 0.34 0.0341 2.74 0.34 0.0301 2.73 3.8694 1.0 2078774 Maybridge3_006415 CCOC(=O)c1c(C)nn(c1C)c2ccc(NC(=O)c3cccs3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D14 compound treatment 0.325 0.0191 1.54 0.32 0.0101 0.91 1.7316 0.9693 2078775 Maybridge3_006416 c1cc(cs1)c2nn[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D15 compound treatment 0.316 0.0101 0.81 0.323 0.0131 1.19 1.4117 0.9827 2078776 Maybridge3_006417 Cc1nc(no1)c2ccc(cc2)c3noc(C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D16 compound treatment 0.333 0.0271 2.18 0.336 0.0261 2.37 3.2141 0.9992 2078777 Maybridge3_006418 COC(=O)Cc1nc(sc1C)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D17 compound treatment 0.325 0.0191 1.54 0.331 0.0211 1.91 2.4376 0.9941 2078778 Maybridge3_006419 FC(F)(F)C(=O)N1CCC(CC1)C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D18 compound treatment 0.323 0.0171 1.37 0.324 0.0141 1.28 1.8744 0.9993 2078779 Maybridge3_006420 FC(F)(F)c1cc(Cl)c(c(Cl)c1)S(=O)(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D19 compound treatment 0.327 0.0211 1.7 0.332 0.0221 2.0 2.6157 0.9966 1140498 Maybridge3_006421 Cc1nc(C)c(C(=O)O)c(c2cccs2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D20 compound treatment 0.33 0.0241 1.94 0.332 0.0221 2.0 2.7865 0.9999 1348447 Maybridge3_006422 CS(=O)(=O)CS(=O)(=O)Nc1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D21 compound treatment 0.318 0.0121 0.97 0.324 0.0141 1.28 1.5897 0.9909 2078780 Maybridge3_006423 N#Cc1ccc(Oc2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D22 compound treatment 0.325 0.0191 1.54 0.327 0.0171 1.55 2.1809 1.0 2078781 Maybridge3_006424 Clc1ccc(cc1)S(=O)(=O)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D23 mock treatment 0.301 -0.00494 -0.4 0.305 -0.00493 -0.45 -0.5978 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 D24 positive control 0.092 -0.214 -17.23 0.093 -0.217 -19.69 -26.1057 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E01 compound treatment 0.322 0.0161 1.29 0.328 0.0181 1.64 2.0742 0.9931 2078782 Maybridge3_006425 COC(=O)c1[nH]c(c(C)c1C(=O)OC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E02 compound treatment 0.318 0.0121 0.97 0.323 0.0131 1.19 1.5255 0.9951 2078783 Maybridge3_006426 FC(F)(F)c1cccc(c1)c2nc(no2)c3ccc(s3)c4ccon4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E03 compound treatment 0.32 0.0141 1.13 0.326 0.0161 1.46 1.832 0.9922 1223351 Maybridge3_006427 O=C(CCSc1cccs1)Nc2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E04 compound treatment 0.319 0.0131 1.05 0.324 0.0141 1.28 1.6467 0.9954 2078784 Maybridge3_006428 CC(=O)N/C(=C\c1ccc(Cl)cc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E05 compound treatment 0.34 0.0341 2.74 0.342 0.0321 2.91 3.9977 0.9996 1162726 Maybridge3_006429 NC(=O)c1ccc(cc1)c2ncc3CSc4sccc4-c3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E06 compound treatment 0.347 0.0411 3.31 0.352 0.0421 3.82 5.0382 0.9974 2078785 Maybridge3_006430 O=C(CC#N)c1ccsc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E07 compound treatment 0.322 0.0161 1.29 0.324 0.0141 1.28 1.8175 1.0 2078786 Maybridge3_006431 CCOC(=O)c1ncoc1c2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E08 compound treatment 0.331 0.0251 2.02 0.333 0.0231 2.09 2.9076 0.9998 2078787 Maybridge3_006432 FC(F)(F)c1sc(cc1c2ccccc2)C(=O)N3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E09 compound treatment 0.314 0.00806 0.65 0.325 0.0151 1.37 1.4261 0.942 1184788 Maybridge3_006433 COc1ccccc1c2nc(COc3ccc(Cl)cc3Cl)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E10 compound treatment 0.331 0.0251 2.02 0.333 0.0231 2.09 2.9076 0.9998 1541267 Maybridge3_006434 Nc1nccnc1C(=O)Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E11 compound treatment 0.321 0.0151 1.21 0.325 0.0151 1.37 1.8247 0.9982 2078788 Maybridge3_006435 NC(=O)c1cc2sccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E12 compound treatment 0.322 0.0161 1.29 0.326 0.0161 1.46 1.9459 0.9982 2078789 Maybridge3_006436 Cc1noc(c1C(=O)O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E13 compound treatment 0.328 0.0221 1.78 0.333 0.0231 2.09 2.7368 0.9967 1403697 Maybridge3_006437 OC(=O)CCSC1=CCS(=O)(=O)c2ccc(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E14 compound treatment 0.314 0.00806 0.65 0.316 0.00607 0.55 0.8485 0.9966 2078790 Maybridge3_006438 Nc1csc(c1c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E15 compound treatment 0.321 0.0151 1.21 0.334 0.0241 2.18 2.4024 0.9615 2078791 Maybridge3_006439 Nc1n[nH]c(NCc2ccccc2OC(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E16 compound treatment 0.318 0.0121 0.97 0.323 0.0131 1.19 1.5255 0.9951 2078792 Maybridge3_006440 CC(C)C(=O)Nc1csc(c1c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E17 compound treatment 0.39 0.0841 6.77 0.388 0.0781 7.09 9.7973 0.9997 1574811 Maybridge3_006441 NC(=O)c1ccc(cc1)c2ncc3COc4ccc(F)cc4-c3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E18 compound treatment 0.325 0.0191 1.54 0.329 0.0191 1.73 2.3092 0.9982 1420963 Maybridge3_006442 CSc1ccsc1C2=NC(C)(C)CO2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E19 compound treatment 0.308 0.00206 0.17 0.311 0.00107 0.1 0.1859 0.967 2078793 Maybridge3_006443 FC(F)(F)c1cccc(c1)c2noc(n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E20 compound treatment 0.326 0.0201 1.62 0.33 0.0201 1.82 2.4304 0.9982 2078794 Maybridge3_006444 COC(=O)c1cc(O)n(n1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E21 compound treatment 0.382 0.0761 6.13 0.394 0.0841 7.63 9.7269 0.9941 2078795 Maybridge3_006445 COc1ccc(/N=C/C2=C(Cl)c3cc(F)ccc3OC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E22 compound treatment 0.323 0.0171 1.37 0.327 0.0171 1.55 2.067 0.9982 2078796 Maybridge3_006446 CC(C)(C)C(=O)Nc1c(Cl)cccc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E23 mock treatment 0.302 -0.00394 -0.32 0.305 -0.00493 -0.45 -0.5409 -0.9857 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 E24 positive control 0.096 -0.21 -16.91 0.096 -0.214 -19.42 -25.6853 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F01 compound treatment 0.322 0.0161 1.29 0.327 0.0171 1.55 2.01 0.996 2078797 Maybridge3_006447 CSc1ccc(s1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F02 compound treatment 0.312 0.00606 0.49 0.327 0.0171 1.55 1.4406 0.8869 2078798 Maybridge3_006448 FC(F)(F)c1cc(n(n1)c2ccc(cc2)N3C(=O)CSCC3=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F03 compound treatment 0.319 0.0131 1.05 0.327 0.0171 1.55 1.8392 0.9822 1498048 Maybridge3_006449 Cn1cnnc1SCc2nc(no2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F04 compound treatment 0.317 0.0111 0.89 0.323 0.0131 1.19 1.4686 0.99 2078799 Maybridge3_006450 COC(=O)c1conc1C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F05 compound treatment 0.351 0.0451 3.63 0.35 0.0401 3.64 5.1376 1.0 1309950 Maybridge3_006451 Clc1ccc(cc1)C(=O)Oc2ccc(cc2)c3nn[nH]c3C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F06 compound treatment 0.298 -0.00794 -0.64 0.326 0.0161 1.46 0.5793 0.3638 2078800 Maybridge3_006452 CCCS(=O)(=O)/C(=C/c1ccc(s1)c2ccc(OC)cc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F07 compound treatment 0.31 0.00406 0.33 0.316 0.00607 0.55 0.6207 0.9691 1271345 Maybridge3_006453 COCc1cc(cc2COCOc12)C(=O)Nc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F08 compound treatment 0.314 0.00806 0.65 0.325 0.0151 1.37 1.4261 0.942 2078801 Maybridge3_006454 Cc1nnsc1C(=O)OCc2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F09 compound treatment 0.314 0.00806 0.65 0.323 0.0131 1.19 1.2978 0.9598 2078802 Maybridge3_006455 Fc1ccc(c(F)c1)S(=O)(=O)Nc2cccc(c2)c3nnco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F10 compound treatment 0.329 0.0231 1.86 0.336 0.0261 2.37 2.9863 0.9928 2078803 Maybridge3_006456 Cn1nc(c(c1NC(=O)CCC(=O)O)c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F11 compound treatment 0.318 0.0121 0.97 0.331 0.0211 1.91 2.039 0.9507 2078804 Maybridge3_006457 FC(F)(F)c1ccc(nc1)N2CCNCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F12 compound treatment 0.44 0.134 10.8 0.438 0.128 11.62 15.8536 0.9993 2078805 Maybridge3_006458 Cc1cc(C)c(/C=C(\C#N)/S(=O)(=O)c2ccccc2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F13 compound treatment 0.341 0.0351 2.82 0.354 0.0441 4.0 4.8249 0.9855 2078806 Maybridge3_006459 CCOC(=O)c1c(C)nn(c1C)c2ccc(NC(=O)C(C)(C)C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F14 compound treatment 0.337 0.0311 2.5 0.339 0.0291 2.64 3.6344 0.9996 2078807 Maybridge3_006460 O/N=C/c1ccc(o1)c2ccccc2OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F15 compound treatment 0.324 0.0181 1.45 0.322 0.0121 1.1 1.803 0.9902 2078808 Maybridge3_006461 Cc1nn(c(C)c1c2nnc(o2)c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F16 compound treatment 0.32 0.0141 1.13 0.322 0.0121 1.1 1.5752 0.9999 2078809 Maybridge3_006462 Fc1ccc2SC/C(=C\c3cccs3)/C(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F17 compound treatment 0.345 0.0391 3.15 0.345 0.0351 3.18 4.475 1.0 1597083 Maybridge3_006463 Cc1nc(C)c(s1)S(=O)(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F18 compound treatment 0.323 0.0171 1.37 0.325 0.0151 1.37 1.9386 1.0 2078810 Maybridge3_006464 Fc1cccc(F)c1S(=O)(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F19 compound treatment 0.349 0.0431 3.47 0.352 0.0421 3.82 5.1521 0.9988 1734478 Maybridge3_006465 Cc1ccc(C)n1CCN2CCN(CC2)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F20 compound treatment 0.339 0.0331 2.66 0.344 0.0341 3.09 4.0692 0.9972 2078811 Maybridge3_006466 O=C/1Nc2ccccc2\C1=C\c3ccc(Oc4ccccc4)nc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F21 compound treatment 0.328 0.0221 1.78 0.332 0.0221 2.0 2.6726 0.9982 2078812 Maybridge3_006467 CCSc1ccc(cn1)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F22 compound treatment 0.333 0.0271 2.18 0.333 0.0231 2.09 3.0215 0.9998 1297121 Maybridge3_006468 CCOC(=O)N1CCN(CC1)c2ccccc2OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F23 mock treatment 0.307 0.00106 0.09 0.309 -9.33E-4 -0.08 6.0E-4 0.0049 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 F24 positive control 0.093 -0.213 -17.15 0.095 -0.215 -19.51 -25.9204 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G01 compound treatment 0.322 0.0161 1.29 0.327 0.0171 1.55 2.01 0.996 2078813 Maybridge3_006469 FC(F)(F)c1cccc(OCc2noc(n2)c3ccsc3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G02 compound treatment 0.317 0.0111 0.89 0.322 0.0121 1.1 1.4044 0.9947 1489219 Maybridge3_006470 OC(=O)c1sc(C(=O)O)c(c2ccco2)c1c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G03 compound treatment 0.321 0.0151 1.21 0.327 0.0171 1.55 1.9531 0.9927 2078814 Maybridge3_006471 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)c(F)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G04 compound treatment 0.304 -0.00194 -0.16 0.312 0.00207 0.19 0.0223 0.0915 2078815 Maybridge3_006472 Clc1ccc(SCc2ccsc2c3ncns3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G05 compound treatment 0.313 0.00706 0.57 0.329 0.0191 1.73 1.6259 0.8925 2078816 Maybridge3_006473 COC(=O)c1sccc1c2ccc(o2)c3cc[nH]n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G06 compound treatment 0.3 -0.00594 -0.48 0.315 0.00507 0.46 -0.0129 -0.0194 1599828 Maybridge3_006474 O=C(N(Cc1cccs1)Cc2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G07 compound treatment 0.317 0.0111 0.89 0.33 0.0201 1.82 1.9179 0.9459 2078817 Maybridge3_006475 Cc1ccc(cc1)c2ocnc2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G08 compound treatment 0.309 0.00306 0.25 0.321 0.0111 1.0 0.8847 0.8553 2078818 Maybridge3_006476 FC(F)(F)c1sc(cc1c2ccccc2)C(=O)Nc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G09 compound treatment 0.313 0.00706 0.57 0.313 0.00307 0.28 0.599 0.946 2078819 Maybridge3_006477 FC(F)(F)c1cccc(c1)c2ocnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G10 compound treatment 0.296 -0.00994 -0.8 0.304 -0.00593 -0.54 -0.9467 -0.9814 1340717 Maybridge3_006478 COc1ccc(SCC(O)CNCc2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G11 compound treatment 0.309 0.00306 0.25 0.317 0.00707 0.64 0.628 0.9138 2078820 Maybridge3_006479 O=C(Sc1cccs1)C2CC3CCC2C=C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G12 compound treatment 0.323 0.0171 1.37 0.329 0.0191 1.73 2.1953 0.9935 2078821 Maybridge3_006480 CC(O)(CS(=O)(=O)c1ccc(Cl)cc1)CS(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G13 compound treatment 0.312 0.00606 0.49 0.32 0.0101 0.91 0.9913 0.9569 2078822 Maybridge3_006481 FC(F)(F)Oc1ccc(cc1)C(=O)NCCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G14 compound treatment 0.309 0.00306 0.25 0.31 6.67E-5 0.01 0.1787 0.7242 1277177 Maybridge3_006482 OC(CNc1ccc(Cl)cc1)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G15 compound treatment 0.297 -0.00894 -0.72 0.303 -0.00693 -0.63 -0.9539 -0.9978 1509851 Maybridge3_006483 COc1ccc(cc1)C(=O)c2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G16 compound treatment 0.342 0.0361 2.9 0.347 0.0371 3.36 4.4326 0.9973 2078823 Maybridge3_006484 OC(=O)C/C(=C/c1ccc(s1)c2cccs2)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G17 compound treatment 0.337 0.0311 2.5 0.343 0.0331 3.0 3.8911 0.9959 1178195 Maybridge3_006485 Cc1nc(ncc1c2nsc(Nc3ccccc3)n2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G18 compound treatment 0.312 0.00606 0.49 0.31 6.67E-5 0.01 0.3495 0.7158 2078824 Maybridge3_006486 Clc1c(sc2sccc12)C(=O)OCc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G19 compound treatment 0.321 0.0151 1.21 0.32 0.0101 0.91 1.5038 0.9903 2078825 Maybridge3_006487 COc1ccccc1c2nc(no2)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G20 compound treatment 0.328 0.0221 1.78 0.335 0.0251 2.28 2.8652 0.9925 2078826 Maybridge3_006488 CCOC(=O)c1cc2c(C)nccn2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G21 compound treatment 0.329 0.0231 1.86 0.332 0.0221 2.0 2.7295 0.9993 2078827 Maybridge3_006489 OC(=O)c1ccccc1C(=O)NCc2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G22 compound treatment 0.322 0.0161 1.29 0.323 0.0131 1.19 1.7533 0.9991 2078828 Maybridge3_006490 CSc1cccc(OC(F)(F)F)c1NC(=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G23 mock treatment 0.303 -0.00294 -0.24 0.305 -0.00493 -0.45 -0.4839 -0.9555 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 G24 positive control 0.099 -0.207 -16.66 0.097 -0.213 -19.33 -25.4503 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H01 compound treatment 0.334 0.0281 2.26 0.348 0.0381 3.46 4.0412 0.9788 2078829 Maybridge3_006491 O/N=C/c1c(nc2SCCn12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H02 compound treatment 0.322 0.0161 1.29 0.326 0.0161 1.46 1.9459 0.9982 1611173 Maybridge3_006492 Cc1cc(C(=O)NCc2ccco2)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H03 compound treatment 0.313 0.00706 0.57 0.317 0.00707 0.64 0.8557 0.9982 2078830 Maybridge3_006493 Clc1ccc(CSCc2nc(no2)c3ccsc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H04 compound treatment 0.325 0.0191 1.54 0.33 0.0201 1.82 2.3734 0.9964 2078831 Maybridge3_006494 Oc1ccc(cc1)c2nnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H05 compound treatment 0.342 0.0361 2.9 0.34 0.0301 2.73 3.9833 0.9995 1375843 Maybridge3_006495 CC(C)(C)CC(=O)Oc1ccc(cc1)c2nn[nH]c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H06 compound treatment 0.318 0.0121 0.97 0.325 0.0151 1.37 1.6539 0.9859 2078832 Maybridge3_006496 Fc1cc(F)cc(CC(=O)Nc2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H07 compound treatment 0.314 0.00806 0.65 0.326 0.0161 1.46 1.4903 0.9336 2078833 Maybridge3_006497 N/C(=N\O)/C1(CC1)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H08 compound treatment 0.336 0.0301 2.42 0.355 0.0451 4.09 4.6044 0.9687 2078834 Maybridge3_006498 C(=N/c1ccccc1n2cccc2)\c3c[nH]c(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H09 compound treatment 0.379 0.0731 5.88 0.381 0.0711 6.45 8.7217 0.9989 2078835 Maybridge3_006499 CN(C)c1cc(cnc1C#N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H10 compound treatment 0.321 0.0151 1.21 0.325 0.0151 1.37 1.8247 0.9982 2078836 Maybridge3_006500 Clc1ccc(/N=C/c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H11 compound treatment 0.402 0.0961 7.74 0.404 0.0941 8.54 11.5076 0.9988 1706804 Maybridge3_006501 NC(=O)C1CCN(CC1)c2cnc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H12 compound treatment 0.312 0.00606 0.49 0.327 0.0171 1.55 1.4406 0.8869 2078837 Maybridge3_006502 Cc1nn(c(C)c1C(=O)N)c2c(Cl)cc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H13 compound treatment 0.333 0.0271 2.18 0.334 0.0241 2.18 3.0857 1.0 2078838 Maybridge3_006503 Cc1cc(C)n(n1)c2ccc(N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H14 compound treatment 0.32 0.0141 1.13 0.324 0.0141 1.28 1.7036 0.9982 1225492 Maybridge3_006504 OC(=O)c1ccc(cc1)c2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H15 compound treatment 0.33 0.0241 1.94 0.315 0.00507 0.46 1.6953 0.8513 2078839 Maybridge3_006505 Cc1nn(c(C)c1c2nnc(o2)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H16 compound treatment 0.376 0.0701 5.64 0.372 0.0621 5.63 7.9732 1.0 2078840 Maybridge3_006506 COc1cc2NC(=O)/C(=C\c3cccs3)/c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H17 compound treatment 0.34 0.0341 2.74 0.354 0.0441 4.0 4.768 0.9831 2078841 Maybridge3_006507 Cc1cc(C)n(n1)c2ccc(cc2)n3cccc3/C=C(\C#N)/S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H18 compound treatment 0.335 0.0291 2.34 0.327 0.0171 1.55 2.7503 0.9799 2078842 Maybridge3_006508 COc1cc(cc(c1C(=O)N)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H19 compound treatment 0.36 0.0541 4.35 0.361 0.0511 4.64 6.3561 0.9995 2078843 Maybridge3_006509 Cc1ccc(C)n1CCN2CCN(CC2)C(=O)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H20 compound treatment 0.331 0.0251 2.02 0.333 0.0231 2.09 2.9076 0.9998 1172566 Maybridge3_006510 CS(=O)(=O)CS(=O)(=O)NCc1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H21 compound treatment 0.328 0.0221 1.78 0.332 0.0221 2.0 2.6726 0.9982 1603848 Maybridge3_006511 CCSc1ccc(cn1)c2noc(n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H22 compound treatment 0.323 0.0171 1.37 0.329 0.0191 1.73 2.1953 0.9935 2078844 Maybridge3_006512 CCCOc1ccc(NC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H23 mock treatment 0.303 -0.00294 -0.24 0.31 6.67E-5 0.01 -0.163 -0.6888 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 H24 positive control 0.097 -0.209 -16.83 0.1 -0.21 -19.06 -25.3717 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I01 compound treatment 0.326 0.0201 1.62 0.333 0.0231 2.09 2.6229 0.9918 2078845 Maybridge3_006513 N#Cc1ccc(OCc2noc(n2)c3ccsc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I02 compound treatment 0.33 0.0241 1.94 0.335 0.0251 2.28 2.979 0.9968 2078846 Maybridge3_006514 c1csc(c1)c2nc(no2)c3ccc(s3)c4ccon4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I03 compound treatment 0.346 0.0401 3.23 0.355 0.0451 4.09 5.1738 0.9931 2078847 Maybridge3_006515 O/N=C/C1=C(Cl)c2cc(Cl)ccc2OC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I04 compound treatment 0.316 0.0101 0.81 0.322 0.0121 1.1 1.3475 0.989 1534529 Maybridge3_006516 Brc1cc(Br)c(s1)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I05 compound treatment 0.324 0.0181 1.45 0.332 0.0221 2.0 2.4448 0.9876 2078848 Maybridge3_006517 COC(=O)c1sccc1c2ccc(o2)c3ccn(n3)C(=O)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I06 compound treatment 0.322 0.0161 1.29 0.321 0.0111 1.0 1.6249 0.9922 2078849 Maybridge3_006518 CSc1sccc1/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I07 compound treatment 0.319 0.0131 1.05 0.328 0.0181 1.64 1.9034 0.977 2078850 Maybridge3_006519 Cc1ccc(cc1)c2ocnc2C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I08 compound treatment 0.322 0.0161 1.29 0.324 0.0141 1.28 1.8175 1.0 2078851 Maybridge3_006520 CC1(C)CC(=O)C=C(C1)Nc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I09 compound treatment 0.328 0.0221 1.78 0.332 0.0221 2.0 2.6726 0.9982 2078852 Maybridge3_006521 Clc1ccccc1c2ocnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I10 compound treatment 0.324 0.0181 1.45 0.328 0.0181 1.64 2.1881 0.9982 2078853 Maybridge3_006522 CNc1nc(nc(C)c1Cl)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I11 compound treatment 0.325 0.0191 1.54 0.316 0.00607 0.55 1.4748 0.9043 2078854 Maybridge3_006523 Cc1nsc(n1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I12 compound treatment 0.327 0.0211 1.7 0.332 0.0221 2.0 2.6157 0.9966 1131491 Maybridge3_006524 COc1ccc(cc1)c2csc(Nc3cccnc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I13 compound treatment 0.329 0.0231 1.86 0.336 0.0261 2.37 2.9863 0.9928 2078855 Maybridge3_006525 O/N=C/c1ccc(s1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I14 compound treatment 0.323 0.0171 1.37 0.315 0.00507 0.46 1.2968 0.895 1396794 Maybridge3_006526 COc1ccc(CNCC(O)CSc2ccc(OC)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I15 compound treatment 0.306 6.25E-5 0.01 0.301 -0.00893 -0.81 -0.5698 -0.7027 2078856 Maybridge3_006527 Fc1ccc(C(=O)c2ccc(s2)c3cccs3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I16 compound treatment 0.32 0.0141 1.13 0.328 0.0181 1.64 1.9603 0.9837 2078857 Maybridge3_006528 CS(=O)(=O)Nc1csc(c1c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I17 compound treatment 0.396 0.0901 7.25 0.409 0.0991 8.99 11.4868 0.9943 2078858 Maybridge3_006529 CC(=O)Nc1ccc(cc1)S(=O)(=O)n2nccc2c3ccc(s3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I18 compound treatment 0.333 0.0271 2.18 0.334 0.0241 2.18 3.0857 1.0 2078859 Maybridge3_006530 FC(F)(F)c1cccc(c1)C2CC(=O)CC(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I19 compound treatment 0.317 0.0111 0.89 0.318 0.00807 0.73 1.1477 0.9953 2078860 Maybridge3_006531 O=C(NCc1ccccc1)c2cc3sccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I20 compound treatment 0.332 0.0261 2.1 0.333 0.0231 2.09 2.9646 1.0 2078861 Maybridge3_006532 OC1CS(=O)(=O)CC1S(=O)(=O)Cc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I21 compound treatment 0.336 0.0301 2.42 0.335 0.0251 2.28 3.3207 0.9995 2078862 Maybridge3_006533 OC(=O)/C=C/C(=O)NCc1ccc(s1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I22 compound treatment 0.332 0.0261 2.1 0.331 0.0211 1.91 2.8362 0.9989 2078863 Maybridge3_006534 Brc1cc(sc1Br)S(=O)(=O)NCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I23 mock treatment 0.31 0.00406 0.33 0.314 0.00407 0.37 0.4923 0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 I24 positive control 0.098 -0.208 -16.74 0.099 -0.211 -19.15 -25.3789 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J01 compound treatment 0.341 0.0351 2.82 0.354 0.0441 4.0 4.8249 0.9855 2078864 Maybridge3_006535 CSc1ccc(s1)C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J02 compound treatment 0.332 0.0261 2.1 0.334 0.0241 2.18 3.0287 0.9998 1249057 Maybridge3_006536 COc1cc(NC(=O)c2cc(C)oc2C)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J03 compound treatment 0.332 0.0261 2.1 0.324 0.0141 1.28 2.3869 0.9716 2078865 Maybridge3_006537 Clc1ccc(CS(=O)(=O)Cc2nc(no2)c3ccsc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J04 compound treatment 0.326 0.0201 1.62 0.331 0.0211 1.91 2.4945 0.9965 1224148 Maybridge3_006538 Clc1cccc(Oc2ccc(cc2)c3nnco3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J05 compound treatment 0.318 0.0121 0.97 0.33 0.0201 1.82 1.9748 0.9567 2078866 Maybridge3_006539 CCOC(=O)c1csc(n1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J06 compound treatment 0.322 0.0161 1.29 0.327 0.0171 1.55 2.01 0.996 1689416 Maybridge3_006540 COc1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J07 compound treatment 0.312 0.00606 0.49 0.32 0.0101 0.91 0.9913 0.9569 2078867 Maybridge3_006541 NS(=O)(=O)c1ccc(s1)c2cc(ccn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J08 compound treatment 0.317 0.0111 0.89 0.328 0.0181 1.64 1.7895 0.9589 2078868 Maybridge3_006542 OC(=O)/C(=C/c1ccsc1)/c2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J09 compound treatment 0.325 0.0191 1.54 0.324 0.0141 1.28 1.9883 0.9958 2078869 Maybridge3_006543 CN(C)c1cc(cnc1/C(=N/O)/N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J10 compound treatment 0.316 0.0101 0.81 0.313 0.00307 0.28 0.7698 0.8985 2078870 Maybridge3_006544 Cc1ccc(/N=C/c2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J11 compound treatment 0.32 0.0141 1.13 0.323 0.0131 1.19 1.6394 0.9997 2078871 Maybridge3_006545 FC(F)(F)c1ccc(nc1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J12 compound treatment 0.319 0.0131 1.05 0.326 0.0161 1.46 1.775 0.9871 2078872 Maybridge3_006546 Nc1c(C#N)cnn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J13 compound treatment 0.341 0.0351 2.82 0.349 0.0391 3.55 4.504 0.9936 2078873 Maybridge3_006547 COc1ccc(OC(=O)c2c(C)nn(c2C)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J14 compound treatment 0.322 0.0161 1.29 0.32 0.0101 0.91 1.5607 0.9855 1455677 Maybridge3_006548 Cc1ccc(cc1)c2cc(C(=O)N)c3cc(F)ccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J15 compound treatment 0.323 0.0171 1.37 0.325 0.0151 1.37 1.9386 1.0 2078874 Maybridge3_006549 CC(C)(C)C(=O)N1CCCC1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J16 compound treatment 0.334 0.0281 2.26 0.325 0.0151 1.37 2.565 0.9711 2078875 Maybridge3_006550 Cc1cc(C(=O)Nc2ccc(Cl)cc2)c(o1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J17 compound treatment 0.346 0.0401 3.23 0.342 0.0321 2.91 4.3394 0.9987 2078876 Maybridge3_006551 C/C=C(\C)/C(=O)N1CCC(CC1)C(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J18 compound treatment 0.326 0.0201 1.62 0.327 0.0171 1.55 2.2378 0.9998 2078877 Maybridge3_006552 Cc1nccnc1c2ccnn2C(=O)Nc3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J19 compound treatment 0.3 -0.00594 -0.48 0.305 -0.00493 -0.45 -0.6547 -0.9995 1426779 Maybridge3_006553 NCC(c1c[nH]c2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J20 compound treatment 0.327 0.0211 1.7 0.333 0.0231 2.09 2.6799 0.9945 2078878 Maybridge3_006554 CS(=O)(=O)CS(=O)(=O)Nc1cccc(OC(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J21 compound treatment 0.335 0.0291 2.34 0.342 0.0321 2.91 3.713 0.9942 2078879 Maybridge3_006555 O=C/1OC(=C\C1=C\c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J22 compound treatment 0.314 0.00806 0.65 0.315 0.00507 0.46 0.7843 0.9857 2078880 Maybridge3_006556 COc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(OC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J23 mock treatment 0.303 -0.00294 -0.24 0.308 -0.00193 -0.18 -0.2914 -0.9892 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 J24 positive control 0.097 -0.209 -16.83 0.099 -0.211 -19.15 -25.4358 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K01 compound treatment 0.326 0.0201 1.62 0.334 0.0241 2.18 2.6871 0.989 1221094 Maybridge3_006557 O=S(=O)(Cc1noc(n1)c2ccsc2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K02 compound treatment 0.312 0.00606 0.49 0.322 0.0121 1.1 1.1197 0.9337 2078881 Maybridge3_006558 CC(C)c1nc(no1)c2ccc(s2)c3ccon3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K03 compound treatment 0.323 0.0171 1.37 0.326 0.0161 1.46 2.0028 0.9996 2078882 Maybridge3_006559 COc1ccc2C(=C(CCc2c1)/C=N/O)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K04 compound treatment 0.323 0.0171 1.37 0.33 0.0201 1.82 2.2595 0.9903 2078883 Maybridge3_006560 OC(=O)c1cc(c(s1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K05 compound treatment 0.318 0.0121 0.97 0.327 0.0171 1.55 1.7823 0.9747 2078884 Maybridge3_006561 FC(F)(F)c1ccc(SCc2ccc(cc2)c3ncns3)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K06 compound treatment 0.676 0.37 29.8 0.671 0.361 32.77 44.2468 0.9989 2078885 Maybridge3_006562 CSC(=CC(=O)c1nccs1)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K07 compound treatment 0.314 0.00806 0.65 0.325 0.0151 1.37 1.4261 0.942 1377165 Maybridge3_006563 COc1ccc(cc1)c2ocnc2C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K08 compound treatment 0.305 -9.37E-4 -0.08 0.314 0.00407 0.37 0.2076 0.5511 1247767 Maybridge3_006564 OC(COc1ccc(cc1)c2csnn2)CSc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K09 compound treatment 0.319 0.0131 1.05 0.327 0.0171 1.55 1.8392 0.9822 2078886 Maybridge3_006565 Clc1cccc(c1)c2ocnc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K10 compound treatment 0.323 0.0171 1.37 0.326 0.0161 1.46 2.0028 0.9996 1252523 Maybridge3_006566 Cc1nc(nc(N2CCCC2)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K11 compound treatment 0.322 0.0161 1.29 0.324 0.0141 1.28 1.8175 1.0 2078887 Maybridge3_006567 NC(=O)/C(=C\c1cccs1)/c2ccsc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K12 compound treatment 0.327 0.0211 1.7 0.348 0.0381 3.46 3.6426 0.9463 2078888 Maybridge3_006568 CN(C)C(=O)c1cc(c(s1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K13 compound treatment 0.326 0.0201 1.62 0.324 0.0141 1.28 2.0452 0.9932 2078889 Maybridge3_006569 CC(C)c1nnc(o1)c2cc3sccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K14 compound treatment 0.329 0.0231 1.86 0.33 0.0201 1.82 2.6012 1.0 1349359 Maybridge3_006570 COc1ccc(NCC(O)CSc2ccc(OC)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K15 compound treatment 0.323 0.0171 1.37 0.329 0.0191 1.73 2.1953 0.9935 1205063 Maybridge3_006571 Clc1ccc(OCc2noc(n2)c3ccoc3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K16 compound treatment 0.342 0.0361 2.9 0.342 0.0321 2.91 4.1116 1.0 2078890 Maybridge3_006572 CS(=O)(=O)/C(=C/c1cccn1S(=O)(=O)c2ccccc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K17 compound treatment 0.335 0.0291 2.34 0.328 0.0181 1.64 2.8145 0.9849 1501280 Maybridge3_006573 Cc1nc(ncc1c2nsc(Nc3ccccc3)n2)c4ccncc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K18 compound treatment 0.316 0.0101 0.81 0.32 0.0101 0.91 1.2191 0.9982 2078891 Maybridge3_006574 Nc1cc(n[nH]1)c2cc(c(s2)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K19 compound treatment 0.33 0.0241 1.94 0.326 0.0161 1.46 2.4014 0.9902 2078892 Maybridge3_006575 CC(NC(=O)c1cc2sccc2s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K20 compound treatment 0.32 0.0141 1.13 0.323 0.0131 1.19 1.6394 0.9997 2078893 Maybridge3_006576 Clc1snnc1COc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K21 compound treatment 0.335 0.0291 2.34 0.338 0.0281 2.55 3.4563 0.9991 1705633 Maybridge3_006577 OC(=O)C1C(C2CC1C=C2)C(=O)NCc3ccc(s3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K22 compound treatment 0.33 0.0241 1.94 0.323 0.0131 1.19 2.2088 0.9723 2078894 Maybridge3_006578 FC(F)(F)Oc1cc(Cl)ccc1NC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K23 mock treatment 0.302 -0.00394 -0.32 0.307 -0.00293 -0.27 -0.4125 -0.9962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 K24 positive control 0.099 -0.207 -16.66 0.1 -0.21 -19.06 -25.2578 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L01 compound treatment 0.329 0.0231 1.86 0.334 0.0241 2.18 2.8579 0.9967 1268952 Maybridge3_006579 CSc1ccc(CNC(=O)c2ccc(Cl)cc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L02 compound treatment 0.323 0.0171 1.37 0.333 0.0231 2.09 2.4521 0.9791 2078895 Maybridge3_006580 Fc1ccc(/C=C/2\COC/C(=C\c3ccc(F)cc3)/C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L03 compound treatment 0.319 0.0131 1.05 0.324 0.0141 1.28 1.6467 0.9954 2078896 Maybridge3_006581 Cn1nc(NC(=O)C(F)(F)F)c(c1C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L04 compound treatment 0.323 0.0171 1.37 0.332 0.0221 2.0 2.3879 0.9831 1700210 Maybridge3_006582 CC(C)(C)c1nocc1C(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L05 compound treatment 0.322 0.0161 1.29 0.332 0.0221 2.0 2.331 0.9776 2078897 Maybridge3_006583 OC(=O)/C=C/C(=O)N1CCN(CC1)c2cc(ccn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L06 compound treatment 0.32 0.0141 1.13 0.327 0.0171 1.55 1.8962 0.9881 1451552 Maybridge3_006584 Fc1cc(F)cc(CC(=O)Nc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L07 compound treatment 0.336 0.0301 2.42 0.344 0.0341 3.09 3.8984 0.9927 1599075 Maybridge3_006585 Clc1ccc(SCc2csc(n2)N3CCOCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L08 compound treatment 0.337 0.0311 2.5 0.332 0.0221 2.0 3.1851 0.9939 2078898 Maybridge3_006586 Cn1nc(c(c1N2C(=O)CSCC2=O)c3ccccc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L09 compound treatment 0.316 0.0101 0.81 0.331 0.0211 1.91 1.9251 0.927 2078899 Maybridge3_006587 Cc1nc(cs1)c2cc(Cl)c(Cl)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L10 compound treatment 0.328 0.0221 1.78 0.335 0.0251 2.28 2.8652 0.9925 2078900 Maybridge3_006588 CCOC(=O)Nc1ccc(OC)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L11 compound treatment 0.316 0.0101 0.81 0.322 0.0121 1.1 1.3475 0.989 2078901 Maybridge3_006589 FC(F)(F)c1ccnc(OCCOC(=O)Nc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L12 compound treatment 0.315 0.00906 0.73 0.326 0.0161 1.46 1.5473 0.9488 2078902 Maybridge3_006590 CSc1nn(c(N)c1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L13 compound treatment 0.33 0.0241 1.94 0.335 0.0251 2.28 2.979 0.9968 2078903 Maybridge3_006591 Cc1nn(c(C)c1c2nc(no2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L14 compound treatment 0.315 0.00906 0.73 0.316 0.00607 0.55 0.9054 0.9904 2078904 Maybridge3_006592 CCC(O)c1ccc(cc1)c2ccccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L15 compound treatment 0.325 0.0191 1.54 0.336 0.0261 2.37 2.7585 0.9781 1348389 Maybridge3_006593 CC(=O)N1CCC(CC1)C(=O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L16 compound treatment 0.332 0.0261 2.1 0.333 0.0231 2.09 2.9646 1.0 1081844 Maybridge3_006594 OC(=O)CCOc1ccc(F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L17 compound treatment 0.331 0.0251 2.02 0.336 0.0261 2.37 3.1002 0.9969 1208192 Maybridge3_006595 Cc1nnsc1C(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L18 compound treatment 0.334 0.0281 2.26 0.336 0.0261 2.37 3.271 0.9997 1640708 Maybridge3_006596 Cc1sc(nc1CC(=O)O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L19 compound treatment 0.325 0.0191 1.54 0.336 0.0261 2.37 2.7585 0.9781 1357821 Maybridge3_006597 Cc1noc(C)c1C(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L20 compound treatment 0.323 0.0171 1.37 0.331 0.0211 1.91 2.3237 0.9868 1678952 Maybridge3_006598 CS(=O)(=O)CS(=O)(=O)NCc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L21 compound treatment 0.319 0.0131 1.05 0.323 0.0131 1.19 1.5825 0.9982 2078905 Maybridge3_006599 NCC(c1ccc[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L22 compound treatment 0.322 0.0161 1.29 0.325 0.0151 1.37 1.8817 0.9996 2078906 Maybridge3_006600 COc1ccc(NS(=O)(=O)c2sc(Cl)cc2Br)c(OC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L23 mock treatment 0.307 0.00106 0.09 0.314 0.00407 0.37 0.3215 0.8485 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 L24 positive control 0.098 -0.208 -16.74 0.1 -0.21 -19.06 -25.3147 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M01 compound treatment 0.322 0.0161 1.29 0.328 0.0181 1.64 2.0742 0.9931 2078907 Maybridge3_006601 COC(=O)c1sc-2c(CSc3ccc(Cl)cc23)c1N(C(=O)C)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M02 compound treatment 0.333 0.0271 2.18 0.335 0.0251 2.28 3.1499 0.9998 2078908 Maybridge3_006602 O=C(NC(=O)c1ccc(s1)c2cccs2)SCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M03 compound treatment 0.319 0.0131 1.05 0.327 0.0171 1.55 1.8392 0.9822 2078909 Maybridge3_006603 CN(NC1OC(=O)c2ccccc12)c3ncc(Cl)cc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M04 compound treatment 0.312 0.00606 0.49 0.318 0.00807 0.73 0.863 0.9806 2078910 Maybridge3_006604 CC(C)(C)NS(=O)(=O)c1sc(Br)cc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M05 compound treatment 0.31 0.00406 0.33 0.316 0.00607 0.55 0.6207 0.9691 2078911 Maybridge3_006605 OC(=O)c1cc2sccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M06 compound treatment 0.326 0.0201 1.62 0.334 0.0241 2.18 2.6871 0.989 2078912 Maybridge3_006606 FC(F)(F)c1ccc(cc1)c2snc(N3CCOCC3)c2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M07 compound treatment 0.322 0.0161 1.29 0.326 0.0161 1.46 1.9459 0.9982 2078913 Maybridge3_006607 OC(=O)c1ncoc1c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M08 compound treatment 0.32 0.0141 1.13 0.331 0.0211 1.91 2.1529 0.9687 2078914 Maybridge3_006608 Cn1ccc(n1)c2nc3ccccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M09 compound treatment 0.315 0.00906 0.73 0.323 0.0131 1.19 1.3547 0.9728 2078915 Maybridge3_006609 Clc1cc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)c(Cl)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M10 compound treatment 0.339 0.0331 2.66 0.351 0.0411 3.73 4.5185 0.9864 1575476 Maybridge3_006610 CN(Cc1ccccc1)c2nc(nc(C)c2Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M11 compound treatment 0.309 0.00306 0.25 0.309 -9.33E-4 -0.08 0.1145 0.439 2078916 Maybridge3_006611 FC(F)(F)Oc1ccccc1/C=C(\C#N)/S(=O)(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M12 compound treatment 0.336 0.0301 2.42 0.339 0.0291 2.64 3.5774 0.9991 1365988 Maybridge3_006612 COc1ccccc1c2csc(Nc3cccnc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M13 compound treatment 0.319 0.0131 1.05 0.328 0.0181 1.64 1.9034 0.977 2078917 Maybridge3_006613 N#Cc1ccc(s1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M14 compound treatment 0.362 0.0561 4.51 0.362 0.0521 4.73 6.5341 0.9997 2078918 Maybridge3_006614 CS(=O)(=O)/C(=C/c1c(nc2SCCn12)c3ccccc3)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M15 compound treatment 0.335 0.0291 2.34 0.347 0.0371 3.36 4.034 0.9843 2078919 Maybridge3_006615 CC(C)(C)C(=O)n1nccc1c2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M16 compound treatment 0.319 0.0131 1.05 0.316 0.00607 0.55 1.1332 0.9544 2078920 Maybridge3_006616 CS(=O)(=O)Nc1csc2cc(cc(Cl)c12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M17 compound treatment 0.324 0.0181 1.45 0.327 0.0171 1.55 2.1239 0.9995 1691830 Maybridge3_006617 Fc1ccc2OCc3cnc(nc3-c2c1)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M18 compound treatment 0.327 0.0211 1.7 0.333 0.0231 2.09 2.6799 0.9945 2078921 Maybridge3_006618 Cc1nc(no1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M19 compound treatment 0.314 0.00806 0.65 0.32 0.0101 0.91 1.1052 0.986 2078922 Maybridge3_006619 CN(C(=O)c1cc2sccc2s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M20 compound treatment 0.322 0.0161 1.29 0.325 0.0151 1.37 1.8817 0.9996 2078923 Maybridge3_006620 OC1CS(=O)(=O)CC1S(=O)(=O)Cc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M21 compound treatment 0.326 0.0201 1.62 0.329 0.0191 1.73 2.3662 0.9994 2078924 Maybridge3_006621 Cc1cc(cc(C)c1C(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M22 compound treatment 0.321 0.0151 1.21 0.327 0.0171 1.55 1.9531 0.9927 1433456 Maybridge3_006622 CC(=O)Nc1ccc2OCOCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M23 mock treatment 0.312 0.00606 0.49 0.307 -0.00293 -0.27 0.1569 0.2822 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 M24 positive control 0.1 -0.206 -16.58 0.101 -0.209 -18.97 -25.1367 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N01 compound treatment 0.323 0.0171 1.37 0.328 0.0181 1.64 2.1312 0.9961 1297169 Maybridge3_006623 CSc1ccc(CNC(=O)c2cccs2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N02 compound treatment 0.336 0.0301 2.42 0.342 0.0321 2.91 3.77 0.9958 2078925 Maybridge3_006624 Clc1ccc(cc1)S(=O)(=O)n2cc3COCCc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N03 compound treatment 0.309 0.00306 0.25 0.316 0.00607 0.55 0.5638 0.9344 2078926 Maybridge3_006625 Fc1ccc(cc1)c2csc(n2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N04 compound treatment 0.315 0.00906 0.73 0.319 0.00907 0.82 1.098 0.9982 1443238 Maybridge3_006626 CC(C)(C)c1nocc1C(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N05 compound treatment 0.321 0.0151 1.21 0.328 0.0181 1.64 2.0173 0.989 2078927 Maybridge3_006627 Cc1cc(C)n(n1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N06 compound treatment 0.327 0.0211 1.7 0.331 0.0211 1.91 2.5515 0.9982 1216798 Maybridge3_006628 Cc1cc(NC(=O)Cc2cc(F)cc(F)c2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N07 compound treatment 0.318 0.0121 0.97 0.322 0.0121 1.1 1.4613 0.9982 2078928 Maybridge3_006629 CCOc1cc(cnc1/C(=N/O)/N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N08 compound treatment 0.324 0.0181 1.45 0.323 0.0131 1.19 1.8672 0.9949 2078929 Maybridge3_006630 Cn1nc(c(c1NC(=O)C2C(C3CC2C=C3)C(=O)O)c4ccccc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N09 compound treatment 0.342 0.0361 2.9 0.342 0.0321 2.91 4.1116 1.0 2078930 Maybridge3_006631 FC(F)(F)c1ccc(cc1)C(=O)N2CCN(CC2)c3cc(ccn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N10 compound treatment 0.326 0.0201 1.62 0.333 0.0231 2.09 2.6229 0.9918 2078931 Maybridge3_006632 Cc1nnc(o1)c2cc(oc2C(F)(F)F)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N11 compound treatment 0.32 0.0141 1.13 0.337 0.0271 2.46 2.538 0.9382 2078932 Maybridge3_006633 COc1ccc(cc1)c2cn(nc2C)C(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N12 compound treatment 0.327 0.0211 1.7 0.329 0.0191 1.73 2.4231 0.9999 2078933 Maybridge3_006634 NCc1c(Cl)cc(cc1Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N13 compound treatment 0.329 0.0231 1.86 0.338 0.0281 2.55 3.1147 0.9879 2078934 Maybridge3_006635 OC(=O)CCc1nc(no1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N14 compound treatment 0.327 0.0211 1.7 0.33 0.0201 1.82 2.4873 0.9994 1180894 Maybridge3_006636 COc1ccccc1c2nc(CSc3ccccc3N)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N15 compound treatment 0.324 0.0181 1.45 0.33 0.0201 1.82 2.3165 0.9938 2078935 Maybridge3_006637 Cc1cc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)c(C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N16 compound treatment 0.355 0.0491 3.95 0.357 0.0471 4.27 5.8146 0.9992 2078936 Maybridge3_006638 O=S(=O)(/C(=C/c1ccccc1N2CCOCC2)/C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N17 compound treatment 0.326 0.0201 1.62 0.329 0.0191 1.73 2.3662 0.9994 1258535 Maybridge3_006639 Clc1ccc(SCC(=O)N2CCC(CC2)C(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N18 compound treatment 0.915 0.609 49.05 0.91 0.6 54.47 73.1959 0.9986 2078937 Maybridge3_006640 Cc1cc(C)c(C=C2C(=O)CCCC2=O)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N19 compound treatment 0.314 0.00806 0.65 0.318 0.00807 0.73 0.9768 0.9982 2078938 Maybridge3_006641 FC(F)(F)C(=O)NCC(c1c[nH]c2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N20 compound treatment 0.325 0.0191 1.54 0.329 0.0191 1.73 2.3092 0.9982 1511065 Maybridge3_006642 NC(=O)c1sc(C#N)c2CCCCc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N21 compound treatment 0.327 0.0211 1.7 0.334 0.0241 2.18 2.744 0.9922 2078939 Maybridge3_006643 CCS(=O)(=O)c1ccc(C#N)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N22 compound treatment 0.371 0.0651 5.24 0.382 0.0721 6.54 8.3303 0.9939 2078940 Maybridge3_006644 Clc1ccc(cc1)n2cccc2/C=C(\C#N)/S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N23 mock treatment 0.311 0.00506 0.41 0.311 0.00107 0.1 0.3567 0.8514 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 N24 positive control 0.1 -0.206 -16.58 0.1 -0.21 -19.06 -25.2008 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O01 compound treatment 0.331 0.0251 2.02 0.335 0.0251 2.28 3.036 0.9982 2078941 Maybridge3_006645 Clc1ccc(NC(=O)CCSc2cccs2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O02 compound treatment 0.338 0.0321 2.58 0.349 0.0391 3.55 4.3332 0.9878 2078942 Maybridge3_006646 CS/C(=N\C#N)/NCc1ccc(s1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O03 compound treatment 0.324 0.0181 1.45 0.328 0.0181 1.64 2.1881 0.9982 2078943 Maybridge3_006647 CN(NC1OC(=O)c2ccccc12)c3ncc(cc3Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O04 compound treatment 0.318 0.0121 0.97 0.326 0.0161 1.46 1.7181 0.9805 2078944 Maybridge3_006648 Brc1cc(Br)c(s1)S(=O)(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O05 compound treatment 0.319 0.0131 1.05 0.328 0.0181 1.64 1.9034 0.977 2078945 Maybridge3_006649 FC(F)(F)c1cccc(c1)c2noc(n2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O06 compound treatment 0.353 0.0471 3.79 0.358 0.0481 4.36 5.7649 0.9975 2078946 Maybridge3_006650 Fc1ccc(cc1F)c2cc3ccccc3[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O07 compound treatment 0.319 0.0131 1.05 0.326 0.0161 1.46 1.775 0.9871 2078947 Maybridge3_006651 OC(=O)c1ncoc1c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O08 compound treatment 0.328 0.0221 1.78 0.329 0.0191 1.73 2.4801 0.9999 2078948 Maybridge3_006652 Cn1cc(c(n1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O09 compound treatment 0.329 0.0231 1.86 0.331 0.0211 1.91 2.6654 0.9999 2078949 Maybridge3_006653 COC(=O)c1sccc1c2ccc(/C=N/c3ccc(Cl)cc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O10 compound treatment 0.337 0.0311 2.5 0.341 0.0311 2.82 3.7627 0.9982 1414634 Maybridge3_006654 Cc1nc(nc(NCCc2ccccc2)c1Cl)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O11 compound treatment 0.324 0.0181 1.45 0.329 0.0191 1.73 2.2523 0.9963 2078950 Maybridge3_006655 CC(C)S(=O)(=O)/C(=C/c1ccccc1OC(F)(F)F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O12 compound treatment 0.326 0.0201 1.62 0.33 0.0201 1.82 2.4304 0.9982 1178305 Maybridge3_006656 Cc1ccc(cc1)S(=O)(=O)CC(C)(O)CS(=O)(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O13 compound treatment 0.321 0.0151 1.21 0.326 0.0161 1.46 1.8889 0.9958 2078951 Maybridge3_006657 NC1=C(C#N)C(C2=C(O1)c3cc(F)ccc3OC2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O14 compound treatment 0.324 0.0181 1.45 0.331 0.0211 1.91 2.3807 0.9909 2078952 Maybridge3_006658 CCOC(=O)c1c[nH]c2c(c(sc2c1=O)C(F)(F)F)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O15 compound treatment 0.337 0.0311 2.5 0.342 0.0321 2.91 3.8269 0.9972 2078953 Maybridge3_006659 Fc1ccc(CNS(=O)(=O)c2ccc(s2)c3ccon3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O16 compound treatment 0.336 0.0301 2.42 0.338 0.0281 2.55 3.5132 0.9997 2078954 Maybridge3_006660 FC(F)(F)c1sc(cc1c2ccccc2)C(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O17 compound treatment 0.321 0.0151 1.21 0.327 0.0171 1.55 1.9531 0.9927 2078955 Maybridge3_006661 Clc1cccc(c1)c2noc(n2)c3ccsc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O18 compound treatment 0.331 0.0251 2.02 0.329 0.0191 1.73 2.6509 0.9971 1157141 Maybridge3_006662 OC(=O)Cc1csc(n1)c2cnccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O19 compound treatment 0.333 0.0271 2.18 0.34 0.0301 2.73 3.4708 0.9938 2078956 Maybridge3_006663 Clc1ccc(cc1)C(=O)NCc2ccc(s2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O20 compound treatment 0.331 0.0251 2.02 0.335 0.0251 2.28 3.036 0.9982 2078957 Maybridge3_006664 CCOC(=O)c1csc(n1)c2snnc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O21 compound treatment 0.331 0.0251 2.02 0.333 0.0231 2.09 2.9076 0.9998 2078958 Maybridge3_006665 Cc1oc2c(F)c(F)c(F)c(F)c2c1/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O22 compound treatment 0.325 0.0191 1.54 0.331 0.0211 1.91 2.4376 0.9941 2078959 Maybridge3_006666 FC(F)(F)/C(=C(/C#N)\c1ccccc1)/Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O23 mock treatment 0.318 0.0121 0.97 0.318 0.00807 0.73 1.2046 0.9903 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 O24 positive control 0.1 -0.206 -16.58 0.1 -0.21 -19.06 -25.2008 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P01 compound treatment 0.324 0.0181 1.45 0.329 0.0191 1.73 2.2523 0.9963 1288822 Maybridge3_006667 CSc1ccc(CNC(=O)c2c(C)noc2C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P02 compound treatment 0.322 0.0161 1.29 0.328 0.0181 1.64 2.0742 0.9931 2078960 Maybridge3_006668 FC(F)(F)c1cc(cc(c1)S(=O)(=O)n2cc3COCCc3n2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P03 compound treatment 0.319 0.0131 1.05 0.323 0.0131 1.19 1.5825 0.9982 1562117 Maybridge3_006669 O=C(Oc1ccc2C(=O)COc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P04 compound treatment 0.334 0.0281 2.26 0.343 0.0331 3.0 3.7203 0.9902 1384036 Maybridge3_006670 CC(=O)Nc1ccc(OC(=O)c2conc2C(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P05 compound treatment 0.329 0.0231 1.86 0.334 0.0241 2.18 2.8579 0.9967 2078961 Maybridge3_006671 CS(=O)(=O)/C(=C\c1ccc(Cl)s1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P06 compound treatment 0.326 0.0201 1.62 0.331 0.0211 1.91 2.4945 0.9965 2078962 Maybridge3_006672 Cn1nc(c(c1N)c2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P07 compound treatment 0.317 0.0111 0.89 0.32 0.0101 0.91 1.276 0.9999 2078963 Maybridge3_006673 CCOc1cc(cnc1C(=N)N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P08 compound treatment 0.329 0.0231 1.86 0.332 0.0221 2.0 2.7295 0.9993 2078964 Maybridge3_006674 Fc1ccc(/C=N\c2ccc(cc2)n3cccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P09 compound treatment 0.345 0.0391 3.15 0.348 0.0381 3.46 4.6676 0.9989 2078965 Maybridge3_006675 Cc1nnsc1C(=O)N2CCN(CC2)c3cc(ccn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P10 compound treatment 0.322 0.0161 1.29 0.325 0.0151 1.37 1.8817 0.9996 2078966 Maybridge3_006676 COC(=O)c1cc(=O)c2cc(ccc2[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P11 compound treatment 0.32 0.0141 1.13 0.326 0.0161 1.46 1.832 0.9922 2078967 Maybridge3_006677 CC(C)(C)/C(=N/O)/c1cccs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P12 compound treatment 0.327 0.0211 1.7 0.331 0.0211 1.91 2.5515 0.9982 1479523 Maybridge3_006678 Fc1cccc(F)c1NC(=O)CC2(CC3CC4CC(C3)C2)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P13 compound treatment 0.347 0.0411 3.31 0.358 0.0481 4.36 5.4233 0.9906 1973 Maybridge3_006679 Cc1nnsc1C(=O)Nc2ccc(cc2)n3nc(cc3C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P14 compound treatment 0.327 0.0211 1.7 0.326 0.0161 1.46 2.2306 0.9972 2078968 Maybridge3_006680 Fc1ccccc1c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P15 compound treatment 0.343 0.0371 2.98 0.343 0.0331 3.0 4.2328 1.0 2078969 Maybridge3_006681 FC(F)(F)c1cccc(c1)C(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P16 compound treatment 0.434 0.128 10.31 0.43 0.12 10.9 14.9985 0.9996 2078970 Maybridge3_006682 O=C/1Nc2ccccc2\C1=C\c3ccccc3N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P17 compound treatment 0.333 0.0271 2.18 0.336 0.0261 2.37 3.2141 0.9992 1453509 Maybridge3_006683 Clc1ccc(cc1)S(=O)(=O)CC(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P18 compound treatment 0.321 0.0151 1.21 0.324 0.0141 1.28 1.7605 0.9997 1177161 Maybridge3_006684 CC(=O)N(CC(=O)O)c1ccccc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P19 compound treatment 0.323 0.0171 1.37 0.325 0.0151 1.37 1.9386 1.0 1577874 Maybridge3_006685 Cc1ccc(C)n1CCN2CCN(CC2)S(=O)(=O)c3cc(Br)c(Br)s3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P20 compound treatment 0.324 0.0181 1.45 0.327 0.0171 1.55 2.1239 0.9995 2078971 Maybridge3_006686 COC(=S)Nc1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P21 compound treatment 0.324 0.0181 1.45 0.329 0.0191 1.73 2.2523 0.9963 1228323 Maybridge3_006687 Cc1ccc(cc1)C(=O)C2CCNCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P22 compound treatment 0.328 0.0221 1.78 0.331 0.0211 1.91 2.6084 0.9993 1265094 Maybridge3_006688 CCCOc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P23 mock treatment 0.316 0.0101 0.81 0.319 0.00907 0.82 1.1549 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1449 P24 positive control 0.102 -0.204 -16.42 0.103 -0.207 -18.78 -24.8944 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A01 compound treatment 0.331 0.0328 2.64 0.331 0.0337 3.06 4.0306 0.9974 2078972 Maybridge3_006689 COC(=O)/C=C/C(=O)N1CCN(CC1)c2ccccc2OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A02 compound treatment 0.303 0.00481 0.39 0.305 0.00769 0.7 0.7675 0.9615 2078973 Maybridge3_006690 FC(F)(F)c1cccc(CSCCN2C(=O)CCC2=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A03 compound treatment 0.299 8.12E-4 0.07 0.302 0.00469 0.43 0.3471 0.8064 2078974 Maybridge3_006691 COc1ccc(cc1)c2n[nH]cc2/C=C(\C#N)/S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A04 compound treatment 0.307 0.00881 0.71 0.308 0.0107 0.97 1.1878 0.9882 2078975 Maybridge3_006692 CSC(=N)NCc1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A05 compound treatment 0.306 0.00781 0.63 0.305 0.00769 0.7 0.9383 0.9987 1406919 Maybridge3_006693 Cc1noc(C)c1S(=O)(=O)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A06 compound treatment 0.298 -1.88E-4 -0.02 0.301 0.00369 0.33 0.226 0.6745 2078976 Maybridge3_006694 Cc1oc(cc1c2cc[nH]n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A07 compound treatment 0.286 -0.0122 -0.98 0.295 -0.00231 -0.21 -0.8424 -0.8394 2078977 Maybridge3_006695 Nc1ccc(Sc2ccccc2)nc1Sc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A08 compound treatment 0.302 0.00381 0.31 0.304 0.00669 0.61 0.6463 0.9501 1266178 Maybridge3_006696 Cc1oc(cc1c2cc(N)n(C)n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A09 compound treatment 0.301 0.00281 0.23 0.296 -0.00131 -0.12 0.0759 0.2966 1370269 Maybridge3_006697 COc1ccc(cc1)c2nnc(o2)c3c(C)noc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A10 compound treatment 0.297 -0.00119 -0.1 0.3 0.00269 0.24 0.1049 0.4003 1714830 Maybridge3_006698 Cc1c(cc(n1c2ccccc2)C(C)(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A11 compound treatment 0.305 0.00681 0.55 0.31 0.0127 1.15 1.2023 0.9425 2078978 Maybridge3_006699 C/C=C/C(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A12 compound treatment 0.326 0.0278 2.24 0.326 0.0287 2.6 3.425 0.9972 2078979 Maybridge3_006700 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)NCCCN4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A13 compound treatment 0.312 0.0138 1.11 0.309 0.0117 1.06 1.5367 0.9997 2078980 Maybridge3_006701 COc1ccc(/N=C/c2ccccc2N3CCN(C)CC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A14 compound treatment 0.304 0.00581 0.47 0.31 0.0127 1.15 1.1453 0.9213 2078981 Maybridge3_006702 Fc1ccc(cc1F)c2csc(CC#N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A15 compound treatment 0.335 0.0368 2.96 0.339 0.0417 3.78 4.7718 0.9927 1351507 Maybridge3_006703 COc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)c3c(C)cc(C)cc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A16 compound treatment 0.329 0.0308 2.48 0.324 0.0267 2.42 3.4674 0.9999 1137638 Maybridge3_006704 Cc1c(sc2ccccc12)c3csc(CS(=O)(=O)C(C)(C)C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A17 compound treatment 0.289 -0.00919 -0.74 0.291 -0.00631 -0.57 -0.9283 -0.992 2078982 Maybridge3_006705 O=C(c1cccs1)n2nccc2c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A18 compound treatment 0.297 -0.00119 -0.1 0.303 0.00569 0.52 0.2974 0.5665 1632705 Maybridge3_006706 Fc1cccc(c1)c2csc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A19 compound treatment 0.303 0.00481 0.39 0.312 0.0147 1.33 1.2167 0.8764 2078983 Maybridge3_006707 COc1ccccc1N2CCN(C/C(=N/O)/N)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A20 compound treatment 0.322 0.0238 1.92 0.327 0.0297 2.69 3.2614 0.9861 1180116 Maybridge3_006708 CC(C)(C)c1cc(c2nc(no2)c3ccccn3)n(Cc4ccccc4)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A21 compound treatment 0.304 0.00581 0.47 0.303 0.00569 0.52 0.696 0.9988 1166168 Maybridge3_006709 CCOC(=O)c1csc(Nc2ccncc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A22 compound treatment 0.295 -0.00319 -0.26 0.291 -0.00631 -0.57 -0.5867 -0.9344 2078984 Maybridge3_006710 COc1ccc(Br)c(c1)c2nc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A23 mock treatment 0.296 -0.00219 -0.18 0.29 -0.00731 -0.66 -0.5939 -0.8648 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 A24 positive control 0.094 -0.204 -16.44 0.086 -0.211 -19.18 -25.1897 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B01 compound treatment 0.347 0.0488 3.93 0.342 0.0447 4.06 5.6477 0.9999 1630663 Maybridge3_006711 CCCc1ccc(cc1)c2nc(CS(=O)(=O)C(C)(C)C)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B02 compound treatment 0.327 0.0288 2.32 0.325 0.0277 2.51 3.4177 0.9992 2078985 Maybridge3_006712 Cc1cc(O)nc(Cc2c(Cl)cccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B03 compound treatment 0.319 0.0208 1.68 0.316 0.0187 1.7 2.3845 1.0 2078986 Maybridge3_006713 c1csc(c1)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B04 compound treatment 0.324 0.0258 2.08 0.317 0.0197 1.79 2.7334 0.9972 2078987 Maybridge3_006714 CCOC(=O)c1nc(no1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B05 compound treatment 0.327 0.0288 2.32 0.319 0.0217 1.97 3.0326 0.9967 2078988 Maybridge3_006715 Nc1cc(nn1c2ccc(I)cc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B06 compound treatment 0.319 0.0208 1.68 0.313 0.0157 1.42 2.192 0.9967 2078989 Maybridge3_006716 CSc1nnc(O)n1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B07 compound treatment 0.323 0.0248 2.0 0.326 0.0287 2.6 3.2542 0.9914 1354989 Maybridge3_006717 CSc1c(C#N)c(nn1C)c2cc(oc2C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B08 compound treatment 0.316 0.0178 1.43 0.313 0.0157 1.42 2.0212 1.0 2078990 Maybridge3_006718 O=C(Oc1ccc(cc1)C2SCCS2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B09 compound treatment 0.335 0.0368 2.96 0.33 0.0327 2.97 4.1942 1.0 1422760 Maybridge3_006719 COc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B10 compound treatment 0.321 0.0228 1.84 0.311 0.0137 1.24 2.1775 0.9819 2078991 Maybridge3_006720 CN/C(=C(/C(=O)OC)\C(=O)c1ccccc1F)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B11 compound treatment 0.334 0.0358 2.88 0.333 0.0357 3.24 4.3298 0.9983 1170897 Maybridge3_006721 COc1ccc2[nH]c(cc2c1)C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B12 compound treatment 0.32 0.0218 1.76 0.317 0.0197 1.79 2.5057 1.0 2078992 Maybridge3_006722 CCOC(=O)c1cc(n[nH]1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B13 compound treatment 0.318 0.0198 1.6 0.313 0.0157 1.42 2.135 0.9984 1345551 Maybridge3_006723 Cc1ccc(cc1)C(=O)Nc2nn(C)c3cccc(F)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B14 compound treatment 0.319 0.0208 1.68 0.31 0.0127 1.15 1.9994 0.9832 2078993 Maybridge3_006724 COCc1cc(O)nc(n1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B15 compound treatment 0.322 0.0238 1.92 0.316 0.0187 1.7 2.5554 0.9981 2078994 Maybridge3_006725 CCC(=O)Nc1nn(C)c2cccc(F)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B16 compound treatment 0.316 0.0178 1.43 0.312 0.0147 1.33 1.957 0.9993 2078995 Maybridge3_006726 CCOC(=O)c1nc(no1)c2cccc(c2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B17 compound treatment 0.318 0.0198 1.6 0.312 0.0147 1.33 2.0709 0.996 1456423 Maybridge3_006727 CS(=O)(=O)Nc1ccc2[nH]cc(C#N)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B18 compound treatment 0.327 0.0288 2.32 0.323 0.0257 2.33 3.2894 1.0 2078996 Maybridge3_006728 CCOC(=O)CSc1nnc(OCC)n1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B19 compound treatment 0.321 0.0228 1.84 0.319 0.0217 1.97 2.691 0.9994 2078997 Maybridge3_006729 CCCc1c(cnn1c2cc(Cl)cc(Cl)c2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B20 compound treatment 0.319 0.0208 1.68 0.317 0.0197 1.79 2.4487 0.9995 2078998 Maybridge3_006730 Clc1ccc(cc1)c2nc(no2)c3cccc(c3)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B21 compound treatment 0.322 0.0238 1.92 0.321 0.0237 2.15 2.8763 0.9984 1107528 Maybridge3_006731 CSc1nc(n[nH]1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B22 compound treatment 0.322 0.0238 1.92 0.316 0.0187 1.7 2.5554 0.9981 2078999 Maybridge3_006732 FC(F)(F)c1nnc2scc(c3ccc(Cl)cc3)n12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B23 mock treatment 0.303 0.00481 0.39 0.3 0.00269 0.24 0.4465 0.9751 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 B24 positive control 0.087 -0.211 -17.01 0.086 -0.211 -19.18 -25.5883 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C01 compound treatment 0.309 0.0108 0.87 0.303 0.00569 0.52 0.9807 0.9689 2079000 Maybridge3_006733 Cc1oc(N)c(c1C)S(=O)(=O)/C(=C/c2ccc(C)cc2)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C02 compound treatment 0.352 0.0538 4.33 0.344 0.0467 4.24 6.0608 0.9999 1175093 Maybridge3_006734 CCOC(=O)c1sc(CN2CCN(CC2)c3cccc(Cl)c3)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C03 compound treatment 0.328 0.0298 2.4 0.322 0.0247 2.24 3.2821 0.9994 1095917 Maybridge3_006735 CCOC(=O)c1cc(OC(=O)C)c2ccc(OC)c(OC)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C04 compound treatment 0.323 0.0248 2.0 0.321 0.0237 2.15 2.9332 0.9993 2079001 Maybridge3_006736 CCOC(=O)c1c(C)n[nH]c1Nc2cccc(Cl)c2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C05 compound treatment 0.311 0.0128 1.03 0.31 0.0127 1.15 1.5439 0.9985 1355615 Maybridge3_006737 Cc1noc(C)c1S(=O)(=O)NCc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C06 compound treatment 0.318 0.0198 1.6 0.305 0.00769 0.7 1.6216 0.9312 2079002 Maybridge3_006738 COC(=O)c1c(C)[nH]c(C)c1c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C07 compound treatment 0.321 0.0228 1.84 0.317 0.0197 1.79 2.5626 0.9999 2079003 Maybridge3_006739 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C08 compound treatment 0.318 0.0198 1.6 0.305 0.00769 0.7 1.6216 0.9312 1217553 Maybridge3_006740 Cc1oc(cc1c2cc(NC(=O)c3ccccc3)[nH]n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C09 compound treatment 0.328 0.0298 2.4 0.317 0.0197 1.79 2.9612 0.9894 2079004 Maybridge3_006741 CC(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C10 compound treatment 0.317 0.0188 1.51 0.312 0.0147 1.33 2.0139 0.998 1425120 Maybridge3_006742 Cc1cc(C(=O)Nc2ccccc2)c(C)n1Cc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C11 compound treatment 0.32 0.0218 1.76 0.311 0.0137 1.24 2.1206 0.9856 2079005 Maybridge3_006743 CN(C)c1ccc(cn1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C12 compound treatment 0.316 0.0178 1.43 0.309 0.0117 1.06 1.7644 0.989 2079006 Maybridge3_006744 Cc1nc(cs1)c2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C13 compound treatment 0.327 0.0288 2.32 0.317 0.0197 1.79 2.9043 0.9917 2079007 Maybridge3_006745 CN1CCN(CC1)c2ccccc2/C=N/c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C14 compound treatment 0.321 0.0228 1.84 0.317 0.0197 1.79 2.5626 0.9999 1435999 Maybridge3_006746 N#CCc1nc(cs1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C15 compound treatment 0.327 0.0288 2.32 0.322 0.0247 2.24 3.2252 0.9998 2079008 Maybridge3_006747 Brc1ccc(cc1)c2csc(n2)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C16 compound treatment 0.311 0.0128 1.03 0.307 0.00969 0.88 1.3513 0.9968 1502989 Maybridge3_006748 CC(C)(C)S(=O)(=O)Cc1nc(cs1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C17 compound treatment 0.341 0.0428 3.45 0.336 0.0387 3.51 4.9209 1.0 1219997 Maybridge3_006749 Clc1ccc(cc1)C(=O)N2CCC(CC2)c3nc(no3)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C18 compound treatment 0.334 0.0358 2.88 0.325 0.0277 2.51 3.8163 0.9977 1522426 Maybridge3_006750 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C19 compound treatment 0.335 0.0368 2.96 0.325 0.0277 2.51 3.8733 0.9966 1540457 Maybridge3_006751 CC(C)(C)c1cc(n(n1)c2ccc(cc2)N3CC(CC3=O)C(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C20 compound treatment 0.312 0.0138 1.11 0.315 0.0177 1.61 1.9218 0.9839 2079009 Maybridge3_006752 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C21 compound treatment 0.314 0.0158 1.27 0.31 0.0127 1.15 1.7147 0.9987 2079010 Maybridge3_006753 COc1cccc(/C=N/C2CCN(Cc3ccccc3)CC2)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C22 compound treatment 0.317 0.0188 1.51 0.318 0.0207 1.88 2.399 0.9943 2079011 Maybridge3_006754 Fc1ccc(CS(=O)(=O)Cc2noc(n2)c3ccc(OC(F)(F)F)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C23 mock treatment 0.295 -0.00319 -0.26 0.292 -0.00531 -0.48 -0.5225 -0.9564 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 C24 positive control 0.088 -0.21 -16.93 0.087 -0.21 -19.09 -25.4672 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D01 compound treatment 0.327 0.0288 2.32 0.321 0.0237 2.15 3.161 0.9993 2079012 Maybridge3_006755 CCCc1ccc(cc1)c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D02 compound treatment 0.329 0.0308 2.48 0.323 0.0257 2.33 3.4032 0.9995 2079013 Maybridge3_006756 CSc1nc(n[nH]1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D03 compound treatment 0.318 0.0198 1.6 0.312 0.0147 1.33 2.0709 0.996 2079014 Maybridge3_006757 Nc1cc(nn1c2ccc(I)cc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D04 compound treatment 0.319 0.0208 1.68 0.319 0.0217 1.97 2.5771 0.9968 2079015 Maybridge3_006758 Oc1nnc(SCc2ccccc2)n1c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D05 compound treatment 0.353 0.0548 4.41 0.347 0.0497 4.51 6.3103 0.9999 1707178 Maybridge3_006759 Cc1oc(cc1C(=O)N2CCOCC2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D06 compound treatment 0.32 0.0218 1.76 0.319 0.0217 1.97 2.634 0.9984 2079016 Maybridge3_006760 Oc1nnc(SCC#N)n1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D07 compound treatment 0.356 0.0578 4.66 0.342 0.0447 4.06 6.1602 0.9976 1523942 Maybridge3_006761 Cc1oc(cc1C(=O)N2CCN(Cc3ccccc3)CC2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D08 compound treatment 0.316 0.0178 1.43 0.305 0.00769 0.7 1.5077 0.9452 2079017 Maybridge3_006762 O=C(Oc1ccc(cc1)C2SCCS2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D09 compound treatment 0.324 0.0258 2.08 0.312 0.0147 1.33 2.4125 0.977 2079018 Maybridge3_006763 COc1ccc2[nH]c(cc2c1)C(=O)N(C)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D10 compound treatment 0.333 0.0348 2.8 0.323 0.0257 2.33 3.631 0.9958 2079019 Maybridge3_006764 Cc1cc(C)n2nc(SCC#N)nc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D11 compound treatment 0.336 0.0378 3.04 0.326 0.0287 2.6 3.9944 0.997 2079020 Maybridge3_006765 FC(F)(F)Oc1ccc(/C=C/C(=O)N2CCOCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D12 compound treatment 0.324 0.0258 2.08 0.312 0.0147 1.33 2.4125 0.977 2079021 Maybridge3_006766 Cc1cc(COC(=O)Nc2ccc(Cl)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D13 compound treatment 0.326 0.0278 2.24 0.317 0.0197 1.79 2.8473 0.9937 2079022 Maybridge3_006767 Cc1nnsc1C(=O)Nc2nn(C)c3cccc(F)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D14 compound treatment 0.343 0.0448 3.61 0.336 0.0387 3.51 5.0348 0.9999 2079023 Maybridge3_006768 CCSCc1cc(OC(=O)N(C)C)nc(n1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D15 compound treatment 0.318 0.0198 1.6 0.316 0.0187 1.7 2.3276 0.9995 1210243 Maybridge3_006769 COc1cccc(c1)C(=O)Nc2n[nH]c3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D16 compound treatment 0.317 0.0188 1.51 0.313 0.0157 1.42 2.0781 0.9995 2079024 Maybridge3_006770 Cc1cc(c(C)cc1Cl)S(=O)(=O)Cc2ccc(N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D17 compound treatment 0.33 0.0318 2.56 0.326 0.0287 2.6 3.6527 1.0 1633742 Maybridge3_006771 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D18 compound treatment 0.323 0.0248 2.0 0.325 0.0277 2.51 3.19 0.9935 2079025 Maybridge3_006772 Clc1ccccc1OCc2nn[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D19 compound treatment 0.328 0.0298 2.4 0.321 0.0237 2.15 3.2179 0.9985 1028530 Maybridge3_006773 CSc1ncnc(SC)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D20 compound treatment 0.338 0.0398 3.21 0.343 0.0457 4.15 5.1994 0.9919 1535085 Maybridge3_006774 Cc1sc(N)c(C(=O)c2ccc(Cl)cc2)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D21 compound treatment 0.323 0.0248 2.0 0.322 0.0247 2.24 2.9974 0.9984 2079026 Maybridge3_006775 Clc1ccc(cc1)C(=O)CSc2nnc([nH]2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D22 compound treatment 0.321 0.0228 1.84 0.325 0.0277 2.51 3.0761 0.9881 2079027 Maybridge3_006776 Cc1ccc(cc1)c2csc3nnc(n23)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D23 mock treatment 0.299 8.12E-4 0.07 0.301 0.00369 0.33 0.2829 0.8296 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 D24 positive control 0.09 -0.208 -16.76 0.09 -0.207 -18.82 -25.1607 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E01 compound treatment 0.331 0.0328 2.64 0.324 0.0267 2.42 3.5813 0.9991 1325422 Maybridge3_006777 Fc1ccc(C(=O)C2CCN(CC2)C(=O)c3cccs3)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E02 compound treatment 0.348 0.0498 4.01 0.337 0.0397 3.6 5.3837 0.9986 1741895 Maybridge3_006778 CC(C)(C)c1cc(n(n1)c2ccc(cc2)N3C(=O)COCC3=O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E03 compound treatment 0.315 0.0168 1.35 0.312 0.0147 1.33 1.9 1.0 1684489 Maybridge3_006779 N#Cc1ccccc1n2ccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E04 compound treatment 0.335 0.0368 2.96 0.315 0.0177 1.61 3.2314 0.9585 2079028 Maybridge3_006780 CCOC(=O)c1c(C)n[nH]c1Nc2ccc(Br)cc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E05 compound treatment 0.314 0.0158 1.27 0.315 0.0177 1.61 2.0357 0.9934 2079029 Maybridge3_006781 FC(F)(F)Oc1cc(Cl)ccc1NC(=O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E06 compound treatment 0.318 0.0198 1.6 0.313 0.0157 1.42 2.135 0.9984 2079030 Maybridge3_006782 COC(=O)c1c(C)[nH]c(C)c1c2ccon2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E07 compound treatment 0.324 0.0258 2.08 0.318 0.0207 1.88 2.7976 0.9987 1691284 Maybridge3_006783 CC1CN(CC(C)O1)S(=O)(=O)c2c(C)noc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E08 compound treatment 0.343 0.0448 3.61 0.33 0.0327 2.97 4.6497 0.9953 1545811 Maybridge3_006784 Cc1oc(cc1c2cc(NC(=O)c3ccccc3)n(C)n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E09 compound treatment 0.324 0.0258 2.08 0.318 0.0207 1.88 2.7976 0.9987 1430578 Maybridge3_006785 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(C)c(F)c(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E10 compound treatment 0.348 0.0498 4.01 0.342 0.0447 4.06 5.7046 1.0 1366750 Maybridge3_006786 CCOC(=O)c1cc(n(CCCN2CCOCC2)c1C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E11 compound treatment 0.349 0.0508 4.09 0.346 0.0487 4.42 6.0183 0.9993 2079031 Maybridge3_006787 CC(C)(C)SCC(=O)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E12 compound treatment 0.31 0.0118 0.95 0.302 0.00469 0.43 0.9735 0.9342 1039251 Maybridge3_006788 C(Oc1ccc2[nH]ccc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E13 compound treatment 0.342 0.0438 3.53 0.34 0.0427 3.87 5.2346 0.9989 1266254 Maybridge3_006789 CC(=O)N1CCC(CC1)c2nc(no2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E14 compound treatment 0.306 0.00781 0.63 0.306 0.00869 0.79 1.0025 0.9937 2079032 Maybridge3_006790 Cc1ccc(cc1)c2csc(CC#N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E15 compound treatment 0.323 0.0248 2.0 0.322 0.0247 2.24 2.9974 0.9984 1343217 Maybridge3_006791 Fc1cc(F)cc(CC(=O)NCc2ccco2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E16 compound treatment 0.322 0.0238 1.92 0.319 0.0217 1.97 2.7479 0.9999 1525654 Maybridge3_006792 Cc1onc(c1c2csc(CC#N)n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E17 compound treatment 0.332 0.0338 2.72 0.325 0.0277 2.51 3.7024 0.9992 1729544 Maybridge3_006793 COc1ccccc1N2CCN(Cc3nc(cs3)c4ccc(Br)cc4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E18 compound treatment 0.322 0.0238 1.92 0.315 0.0177 1.61 2.4912 0.9961 1608317 Maybridge3_006794 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E19 compound treatment 0.322 0.0238 1.92 0.313 0.0157 1.42 2.3628 0.9893 2079033 Maybridge3_006795 CC(C)(C)c1cc(n(n1)c2cnc3ccccc3n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E20 compound treatment 0.323 0.0248 2.0 0.324 0.0267 2.42 3.1258 0.9954 1389298 Maybridge3_006796 Cc1noc(C)c1c2nc(no2)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E21 compound treatment 0.327 0.0288 2.32 0.323 0.0257 2.33 3.2894 1.0 1433464 Maybridge3_006797 Fc1ccc(CS(=O)(=O)CCNC(=O)c2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E22 compound treatment 0.32 0.0218 1.76 0.316 0.0187 1.7 2.4415 0.9998 2079034 Maybridge3_006798 Fc1ccc(CS(=O)(=O)Cc2noc(n2)c3ccc(F)cc3Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E23 mock treatment 0.293 -0.00519 -0.42 0.292 -0.00531 -0.48 -0.6364 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 E24 positive control 0.091 -0.207 -16.68 0.092 -0.205 -18.64 -24.9754 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F01 compound treatment 0.349 0.0508 4.09 0.346 0.0487 4.42 6.0183 0.9993 1535986 Maybridge3_006799 CSCCn1c(C)c(cc1c2ccccc2)C(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F02 compound treatment 0.326 0.0278 2.24 0.319 0.0217 1.97 2.9757 0.9979 1509413 Maybridge3_006800 Nc1noc(Cc2c(Cl)cccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F03 compound treatment 0.326 0.0278 2.24 0.319 0.0217 1.97 2.9757 0.9979 1281491 Maybridge3_006801 CC(C)(C)S(=O)(=O)Cc1noc(n1)c2ccc(F)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F04 compound treatment 0.354 0.0558 4.49 0.344 0.0467 4.24 6.1747 0.9996 2079035 Maybridge3_006802 CN(C)C(=O)Oc1nnc(SCc2ccccc2)n1c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F05 compound treatment 0.346 0.0478 3.85 0.331 0.0337 3.06 4.8847 0.9935 2079036 Maybridge3_006803 FC(F)(F)c1cc(no1)c2ccc(s2)S(=O)(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F06 compound treatment 0.328 0.0298 2.4 0.319 0.0217 1.97 3.0896 0.9951 2079037 Maybridge3_006804 CSc1nnc(OC(=O)N(C)C)n1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F07 compound treatment 0.329 0.0308 2.48 0.313 0.0157 1.42 2.7614 0.9653 1343530 Maybridge3_006805 CCOC(=O)c1c(C)n(c(C)c1S(=O)(=O)N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F08 compound treatment 0.323 0.0248 2.0 0.319 0.0217 1.97 2.8049 1.0 2079038 Maybridge3_006806 Nc1n[nH]c(SCc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F09 compound treatment 0.326 0.0278 2.24 0.326 0.0287 2.6 3.425 0.9972 1170751 Maybridge3_006807 COc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc(F)cc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F10 compound treatment 0.308 0.00981 0.79 0.307 0.00969 0.88 1.1805 0.9986 2079039 Maybridge3_006808 Nc1nnc(SCC(=O)c2ccc(Cl)cc2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F11 compound treatment 0.311 0.0128 1.03 0.314 0.0167 1.51 1.8006 0.9825 2079040 Maybridge3_006809 CCOC(=O)c1cc(C)n(c1C)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F12 compound treatment 0.315 0.0168 1.35 0.305 0.00769 0.7 1.4507 0.9525 2079041 Maybridge3_006810 N/C(=N\O)/Cc1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F13 compound treatment 0.337 0.0388 3.13 0.336 0.0387 3.51 4.6932 0.9983 2079042 Maybridge3_006811 Cn1nc(NC(=O)/C=C/c2ccc(OC(F)(F)F)cc2)c3c(F)cccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F14 compound treatment 0.327 0.0288 2.32 0.323 0.0257 2.33 3.2894 1.0 2079043 Maybridge3_006812 CSc1nnc(SC)n1NC(=N)c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F15 compound treatment 0.318 0.0198 1.6 0.315 0.0177 1.61 2.2634 1.0 1448160 Maybridge3_006813 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3[nH]ccc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F16 compound treatment 0.319 0.0208 1.68 0.319 0.0217 1.97 2.5771 0.9968 2079044 Maybridge3_006814 CSc1ncc([nH]1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F17 compound treatment 0.322 0.0238 1.92 0.324 0.0267 2.42 3.0688 0.9933 2079045 Maybridge3_006815 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F18 compound treatment 0.327 0.0288 2.32 0.326 0.0287 2.6 3.4819 0.9983 2079046 Maybridge3_006816 Nc1ccc(CS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F19 compound treatment 0.339 0.0408 3.29 0.328 0.0307 2.79 4.2936 0.9966 2079047 Maybridge3_006817 Brc1c(Oc2ccccc2)ncnc1Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F20 compound treatment 0.325 0.0268 2.16 0.323 0.0257 2.33 3.1755 0.9993 2079048 Maybridge3_006818 CSc1ncc(C)cc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F21 compound treatment 0.324 0.0258 2.08 0.325 0.0277 2.51 3.2469 0.9955 2079049 Maybridge3_006819 FC(F)(F)c1nnc(SCC(=O)c2ccccc2)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F22 compound treatment 0.341 0.0428 3.45 0.332 0.0347 3.15 4.6642 0.999 2079050 Maybridge3_006820 CC(C)(C)c1ccc(cc1)c2nnc(CS(=O)(=O)c3ccc(Cl)cc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F23 mock treatment 0.296 -0.00219 -0.18 0.292 -0.00531 -0.48 -0.4655 -0.9068 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 F24 positive control 0.091 -0.207 -16.68 0.091 -0.206 -18.73 -25.0396 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G01 compound treatment 0.327 0.0288 2.32 0.321 0.0237 2.15 3.161 0.9993 1213220 Maybridge3_006821 Cc1noc(C)c1C(=O)N2CCC(CC2)C(=O)c3ccc(F)cc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G02 compound treatment 0.334 0.0358 2.88 0.322 0.0247 2.24 3.6238 0.9922 2079051 Maybridge3_006822 COC(=O)c1cc(/C=C(\C#N)/S(=O)(=O)C)cn1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G03 compound treatment 0.317 0.0188 1.51 0.315 0.0177 1.61 2.2065 0.9996 2079052 Maybridge3_006823 N#Cc1ccccc1N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G04 compound treatment 0.323 0.0248 2.0 0.319 0.0217 1.97 2.8049 1.0 1016395 Maybridge3_006824 CCOC(=O)c1cc(C)[nH]c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G05 compound treatment 0.325 0.0268 2.16 0.319 0.0217 1.97 2.9187 0.9989 1578572 Maybridge3_006825 Cc1noc(C)c1C(=O)NCc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G06 compound treatment 0.324 0.0258 2.08 0.317 0.0197 1.79 2.7334 0.9972 1489870 Maybridge3_006826 Cc1nc(no1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G07 compound treatment 0.332 0.0338 2.72 0.319 0.0217 1.97 3.3173 0.9873 2079053 Maybridge3_006827 Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G08 compound treatment 0.344 0.0458 3.69 0.345 0.0477 4.33 5.6694 0.9968 1173722 Maybridge3_006828 CCOC(=O)c1sc(nc1C)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G09 compound treatment 0.351 0.0528 4.25 0.342 0.0447 4.06 5.8755 0.9997 2079054 Maybridge3_006829 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(C#N)cn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G10 compound treatment 0.355 0.0568 4.57 0.351 0.0537 4.87 6.6809 0.9995 1448264 Maybridge3_006830 CCOC(=O)c1cc(c2ccccc2)n(CCCN3CCOCC3)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G11 compound treatment 0.32 0.0218 1.76 0.319 0.0217 1.97 2.634 0.9984 1663316 Maybridge3_006831 COc1ccc(cc1)N2CC(CC2=O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G12 compound treatment 0.32 0.0218 1.76 0.318 0.0207 1.88 2.5699 0.9994 2079055 Maybridge3_006832 CCOC(=O)Cc1csc(n1)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G13 compound treatment 0.319 0.0208 1.68 0.314 0.0167 1.51 2.2562 0.9987 1183208 Maybridge3_006833 Cc1noc(C)c1c2nc(CSc3ccccc3N)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G14 compound treatment 0.325 0.0268 2.16 0.315 0.0177 1.61 2.662 0.9894 2079056 Maybridge3_006834 N#CCc1nc(cs1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G15 compound treatment 0.315 0.0168 1.35 0.308 0.0107 0.97 1.6433 0.9866 1549456 Maybridge3_006835 Cc1ccc(c(NS(=O)(=O)c2ccc(s2)c3ccon3)c1)n4cccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G16 compound treatment 0.315 0.0168 1.35 0.311 0.0137 1.24 1.8359 0.9991 1242887 Maybridge3_006836 C1COc2ccc(cc2OC1)c3csc(n3)c4ccno4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G17 compound treatment 0.332 0.0338 2.72 0.326 0.0287 2.6 3.7666 0.9998 2079057 Maybridge3_006837 FC(F)(F)c1ccc(cc1)c2nnc(o2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G18 compound treatment 0.349 0.0508 4.09 0.351 0.0537 4.87 6.3392 0.9962 1519247 Maybridge3_006838 Cc1c(cc(c2ccccc2)n1CCCN3CCOCC3)C(=O)Nc4ccccc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G19 compound treatment 0.314 0.0158 1.27 0.315 0.0177 1.61 2.0357 0.9934 2079058 Maybridge3_006839 FC(F)(F)c1ccc(nc1)N2CCN(CC#N)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G20 compound treatment 0.321 0.0228 1.84 0.316 0.0187 1.7 2.4984 0.9992 2079059 Maybridge3_006840 Cc1cccc(c1)c2noc(n2)c3ccc(OC(F)(F)F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G21 compound treatment 0.325 0.0268 2.16 0.323 0.0257 2.33 3.1755 0.9993 2079060 Maybridge3_006841 Fc1ccc(CS(=O)(=O)CCNC(=O)c2cccc(OC(F)(F)F)c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G22 compound treatment 0.318 0.0198 1.6 0.315 0.0177 1.61 2.2634 1.0 1446631 Maybridge3_006842 Fc1ccc(CS(=O)(=O)Cc2noc(n2)C3CCC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G23 mock treatment 0.296 -0.00219 -0.18 0.297 -3.12E-4 -0.03 -0.1446 -0.8105 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 G24 positive control 0.093 -0.205 -16.52 0.093 -0.204 -18.55 -24.7974 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H01 compound treatment 0.327 0.0288 2.32 0.324 0.0267 2.42 3.3535 0.9998 2079061 Maybridge3_006843 FC(F)(F)Oc1ccc(cc1)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H02 compound treatment 0.329 0.0308 2.48 0.324 0.0267 2.42 3.4674 0.9999 2079062 Maybridge3_006844 CC(Oc1ccc(Cl)cc1Cl)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H03 compound treatment 0.308 0.00981 0.79 0.31 0.0127 1.15 1.3731 0.9831 2079063 Maybridge3_006845 CC(C)(C)S(=O)(=O)Cc1noc(n1)c2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H04 compound treatment 0.326 0.0278 2.24 0.326 0.0287 2.6 3.425 0.9972 1171338 Maybridge3_006846 CC(C)(C)C(=O)CC1(O)C(=O)Nc2ccc(Br)cc21 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H05 compound treatment 0.325 0.0268 2.16 0.33 0.0327 2.97 3.6248 0.9878 2079064 Maybridge3_006847 OC1CCN(CC1)S(=O)(=O)c2ccc(s2)c3cc(on3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H06 compound treatment 0.329 0.0308 2.48 0.328 0.0307 2.79 3.7242 0.9983 2079065 Maybridge3_006848 CN(C)C(=O)Oc1nnc(SCC=C)n1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H07 compound treatment 0.334 0.0358 2.88 0.331 0.0337 3.06 4.2014 0.9996 1277898 Maybridge3_006849 COC(=O)c1c(C)n(C)c(C)c1S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H08 compound treatment 0.32 0.0218 1.76 0.319 0.0217 1.97 2.634 0.9984 2079066 Maybridge3_006850 CC(C)Sc1nnc(O)n1c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H09 compound treatment 0.324 0.0258 2.08 0.318 0.0207 1.88 2.7976 0.9987 1667207 Maybridge3_006851 COc1ccc2[nH]c(cc2c1)C(=O)Nc3cccc(C)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H10 compound treatment 0.334 0.0358 2.88 0.333 0.0357 3.24 4.3298 0.9983 2079067 Maybridge3_006852 CSc1cc(nc(O)c1C#N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H11 compound treatment 0.324 0.0258 2.08 0.331 0.0337 3.06 3.632 0.9823 2079068 Maybridge3_006853 Cc1cc(C)c([nH]1)c2ccn(n2)C(=O)c3snnc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H12 compound treatment 0.316 0.0178 1.43 0.32 0.0227 2.06 2.4705 0.9844 2079069 Maybridge3_006854 CCOC(=O)c1cc(C)nn1C(=O)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H13 compound treatment 0.338 0.0398 3.21 0.336 0.0387 3.51 4.7501 0.999 1632666 Maybridge3_006855 CSc1nsc(SC)c1C(=O)Nc2nn(C)c3cccc(F)c23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H14 compound treatment 0.316 0.0178 1.43 0.32 0.0227 2.06 2.4705 0.9844 2079070 Maybridge3_006856 CCN(CC)C(=O)Sc1nc2cc(Cl)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H15 compound treatment 0.312 0.0138 1.11 0.314 0.0167 1.51 1.8576 0.9885 2079071 Maybridge3_006857 OC1(CC(=NO1)c2ccc3ccccc3c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H16 compound treatment 0.322 0.0238 1.92 0.319 0.0217 1.97 2.7479 0.9999 2079072 Maybridge3_006858 Clc1ccc(cc1)c2cnc(SCC=C)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H17 compound treatment 0.32 0.0218 1.76 0.322 0.0247 2.24 2.8266 0.9927 1651899 Maybridge3_006859 COC(=O)c1cc(oc1C)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H18 compound treatment 0.322 0.0238 1.92 0.319 0.0217 1.97 2.7479 0.9999 2079073 Maybridge3_006860 CCOC(=O)c1nc(COc2ccccc2Cl)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H19 compound treatment 0.331 0.0328 2.64 0.337 0.0397 3.6 4.4157 0.9884 2079074 Maybridge3_006861 CCOC(=O)c1cc(C)nc(Sc2ccc(C)cc2)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H20 compound treatment 0.372 0.0738 5.94 0.357 0.0597 5.42 8.034 0.9989 1184010 Maybridge3_006862 Clc1ccc(cc1)c2csc(CS(=O)(=O)c3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H21 compound treatment 0.322 0.0238 1.92 0.321 0.0237 2.15 2.8763 0.9984 2079075 Maybridge3_006863 FC(F)(F)c1n[nH]c(SCc2ccc(Cl)cc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H22 compound treatment 0.321 0.0228 1.84 0.334 0.0367 3.33 3.6538 0.9607 1370956 Maybridge3_006864 CCOC(=O)c1sc(COc2cccc(Cl)c2)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H23 mock treatment 0.298 -1.88E-4 -0.02 0.301 0.00369 0.33 0.226 0.6745 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 H24 positive control 0.093 -0.205 -16.52 0.094 -0.203 -18.45 -24.7332 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I01 compound treatment 0.318 0.0198 1.6 0.321 0.0237 2.15 2.6485 0.9892 2079076 Maybridge3_006865 Nc1oc(nc1C#N)c2ccccc2OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I02 compound treatment 0.33 0.0318 2.56 0.326 0.0287 2.6 3.6527 1.0 1413699 Maybridge3_006866 OC(=O)C1CN(CCc2cccs2)C(=O)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I03 compound treatment 0.33 0.0318 2.56 0.326 0.0287 2.6 3.6527 1.0 2079077 Maybridge3_006867 NC(=O)C1=CCc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I04 compound treatment 0.322 0.0238 1.92 0.321 0.0237 2.15 2.8763 0.9984 2079078 Maybridge3_006868 COC(=O)c1c(C)[nH]c(C)c1/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I05 compound treatment 0.325 0.0268 2.16 0.323 0.0257 2.33 3.1755 0.9993 1690944 Maybridge3_006869 Cc1noc(C)c1C(=O)Oc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I06 compound treatment 0.323 0.0248 2.0 0.318 0.0207 1.88 2.7407 0.9995 1155559 Maybridge3_006870 O=C(NCc1ccc2OCCc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I07 compound treatment 0.324 0.0258 2.08 0.328 0.0307 2.79 3.4395 0.9896 2079079 Maybridge3_006871 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)CSc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I08 compound treatment 0.336 0.0378 3.04 0.329 0.0317 2.88 4.1869 0.9996 1196200 Maybridge3_006872 CCOC(=O)c1csc(n1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I09 compound treatment 0.33 0.0318 2.56 0.321 0.0237 2.15 3.3318 0.9962 1703195 Maybridge3_006873 COc1ccccc1N2CCN(CC2)C(=O)c3cc(C)on3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I10 compound treatment 0.331 0.0328 2.64 0.335 0.0377 3.42 4.2873 0.9919 2079080 Maybridge3_006874 CCOC(=O)c1cc(n(CCSC)c1C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I11 compound treatment 0.319 0.0208 1.68 0.321 0.0237 2.15 2.7055 0.9924 1344469 Maybridge3_006875 OC(=O)C1CN(C(=O)C1)c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I12 compound treatment 0.32 0.0218 1.76 0.318 0.0207 1.88 2.5699 0.9994 1283925 Maybridge3_006876 Cc1c(cc(c2ccccc2)n1CCNC(=O)OC(C)(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I13 compound treatment 0.306 0.00781 0.63 0.317 0.0197 1.79 1.7085 0.9018 1149058 Maybridge3_006877 Clc1ccc(cc1)c2noc(n2)C3CCNCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I14 compound treatment 0.291 -0.00719 -0.58 0.298 6.88E-4 0.06 -0.3651 -0.6272 2079081 Maybridge3_006878 FC(F)(F)c1ccc(cc1)c2csc(CC#N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I15 compound treatment 0.32 0.0218 1.76 0.322 0.0247 2.24 2.8266 0.9927 1484410 Maybridge3_006879 COc1ccccc1N2CCN(CC#N)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I16 compound treatment 0.31 0.0118 0.95 0.314 0.0167 1.51 1.7437 0.9749 1274435 Maybridge3_006880 Cc1ccc(c2csc(n2)c3ccno3)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I17 compound treatment 0.331 0.0328 2.64 0.321 0.0237 2.15 3.3888 0.9948 1363588 Maybridge3_006881 CC(=O)N1CCC(CC1)c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I18 compound treatment 0.328 0.0298 2.4 0.336 0.0387 3.51 4.1807 0.9828 2079082 Maybridge3_006882 Fc1ccc(cc1)S(=O)(=O)Cc2noc(n2)c3ccc(OC(F)(F)F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I19 compound treatment 0.33 0.0318 2.56 0.327 0.0297 2.69 3.7169 0.9997 2079083 Maybridge3_006883 Cc1cccc(c1)N2CCN(CC#N)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I20 compound treatment 0.354 0.0558 4.49 0.352 0.0547 4.96 6.6881 0.9988 1143234 Maybridge3_006884 Cc1c(cc(c2ccccc2)n1CCCN3CCOCC3)C(=O)NCc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I21 compound treatment 0.325 0.0268 2.16 0.322 0.0247 2.24 3.1113 0.9998 1588492 Maybridge3_006885 COc1ccc(cc1)C(=O)NCCS(=O)(=O)Cc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I22 compound treatment 0.325 0.0268 2.16 0.324 0.0267 2.42 3.2397 0.9984 2079084 Maybridge3_006886 CCn1nc(C)c(Br)c1c2nc(no2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I23 mock treatment 0.3 0.00181 0.15 0.299 0.00169 0.15 0.2115 0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 I24 positive control 0.094 -0.204 -16.44 0.094 -0.203 -18.45 -24.6762 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J01 compound treatment 0.328 0.0298 2.4 0.323 0.0257 2.33 3.3463 0.9999 2079085 Maybridge3_006887 Cc1cccc(c1)c2noc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J02 compound treatment 0.323 0.0248 2.0 0.319 0.0217 1.97 2.8049 1.0 2079086 Maybridge3_006888 NC(=N)c1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J03 compound treatment 0.316 0.0178 1.43 0.312 0.0147 1.33 1.957 0.9993 2079087 Maybridge3_006889 Nc1cc(nn1c2ccc(F)cc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J04 compound treatment 0.344 0.0458 3.69 0.342 0.0447 4.06 5.4769 0.9989 1137704 Maybridge3_006890 COCc1cc(OC(=O)N(C)C)nc(Cc2c(Cl)cccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J05 compound treatment 0.328 0.0298 2.4 0.325 0.0277 2.51 3.4747 0.9997 2079088 Maybridge3_006891 CN1CCN(CC1)S(=O)(=O)c2ccc(s2)c3cc(on3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J06 compound treatment 0.339 0.0408 3.29 0.316 0.0187 1.7 3.5234 0.9527 2079089 Maybridge3_006892 CN(C)C(=O)Oc1nnc(SCC=C)n1c2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J07 compound treatment 0.317 0.0188 1.51 0.314 0.0167 1.51 2.1423 1.0 1562863 Maybridge3_006893 CCOC(=O)c1c(C)oc(C)c1S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J08 compound treatment 0.326 0.0278 2.24 0.32 0.0227 2.06 3.0399 0.9991 2079090 Maybridge3_006894 CC(C)Sc1nnc(OC(=O)N(C)C)n1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J09 compound treatment 0.329 0.0308 2.48 0.326 0.0287 2.6 3.5958 0.9997 1607956 Maybridge3_006895 COCC(C)NC(=O)c1cc2cc(OC)ccc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J10 compound treatment 0.367 0.0688 5.54 0.364 0.0667 6.05 8.1986 0.999 2079091 Maybridge3_006896 CSc1cc(nc(O)c1C#N)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J11 compound treatment 0.323 0.0248 2.0 0.318 0.0207 1.88 2.7407 0.9995 2079092 Maybridge3_006897 Cc1cn(nc1c2cccs2)C(=O)c3snnc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J12 compound treatment 0.315 0.0168 1.35 0.318 0.0207 1.88 2.2851 0.9871 2079093 Maybridge3_006898 CCOC(=O)c1cc(C)nn1S(=O)(=O)c2ccc(Cl)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J13 compound treatment 0.319 0.0208 1.68 0.319 0.0217 1.97 2.5771 0.9968 2079094 Maybridge3_006899 Cc1c(cnn1c2ccccc2)c3ccnn3C(=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J14 compound treatment 0.326 0.0278 2.24 0.313 0.0157 1.42 2.5906 0.9761 2079095 Maybridge3_006900 CSc1nnc([nH]1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J15 compound treatment 0.323 0.0248 2.0 0.32 0.0227 2.06 2.869 0.9999 1579339 Maybridge3_006901 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J16 compound treatment 0.322 0.0238 1.92 0.317 0.0197 1.79 2.6195 0.9994 2079096 Maybridge3_006902 O=c1c(coc2ccccc12)C3SCCS3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J17 compound treatment 0.318 0.0198 1.6 0.319 0.0217 1.97 2.5202 0.9946 2079097 Maybridge3_006903 COC(=O)c1cc(oc1C)S(=O)(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J18 compound treatment 0.324 0.0258 2.08 0.315 0.0177 1.61 2.6051 0.9919 2079098 Maybridge3_006904 COCc1cc(O)nc(COc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J19 compound treatment 0.325 0.0268 2.16 0.321 0.0237 2.15 3.0471 1.0 2079099 Maybridge3_006905 CCOC(=O)c1c(Cl)c(nc(Sc2ccccn2)c1C#N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J20 compound treatment 0.331 0.0328 2.64 0.333 0.0357 3.24 4.159 0.9949 1153057 Maybridge3_006906 CCOC(=O)Cc1csc(CS(=O)(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J21 compound treatment 0.325 0.0268 2.16 0.324 0.0267 2.42 3.2397 0.9984 2079100 Maybridge3_006907 Cc1ccc(CSc2nnc([nH]2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J22 compound treatment 0.315 0.0168 1.35 0.315 0.0177 1.61 2.0926 0.9964 2079101 Maybridge3_006908 FC(F)(F)c1ccc(CSc2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J23 mock treatment 0.296 -0.00219 -0.18 0.295 -0.00231 -0.21 -0.273 -0.9962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 J24 positive control 0.094 -0.204 -16.44 0.095 -0.202 -18.36 -24.612 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K01 compound treatment 0.327 0.0288 2.32 0.324 0.0267 2.42 3.3535 0.9998 2079102 Maybridge3_006909 Nc1oc(nc1C#N)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K02 compound treatment 0.326 0.0278 2.24 0.317 0.0197 1.79 2.8473 0.9937 2079103 Maybridge3_006910 Cc1nnsc1C(=O)n2nc(cc2C(C)(C)C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K03 compound treatment 0.321 0.0228 1.84 0.321 0.0237 2.15 2.8193 0.9969 2079104 Maybridge3_006911 CC(C)N(C(C)C)S(=O)(=O)c1c(C)noc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K04 compound treatment 0.33 0.0318 2.56 0.321 0.0237 2.15 3.3318 0.9962 2079105 Maybridge3_006912 Cc1oc(cc1C(=O)O)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K05 compound treatment 0.325 0.0268 2.16 0.325 0.0277 2.51 3.3039 0.9971 2079106 Maybridge3_006913 CC(C)N(C(C)C)C(=O)c1c(C)noc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K06 compound treatment 0.325 0.0268 2.16 0.319 0.0217 1.97 2.9187 0.9989 1706731 Maybridge3_006914 O=C(NCc1ccc2OCCc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K07 compound treatment 0.328 0.0298 2.4 0.33 0.0327 2.97 3.7956 0.9945 2079107 Maybridge3_006915 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K08 compound treatment 0.374 0.0758 6.1 0.368 0.0707 6.42 8.8539 0.9997 1160994 Maybridge3_006916 O=C(Nc1ccccc1)c2cnc(s2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K09 compound treatment 0.35 0.0518 4.17 0.351 0.0537 4.87 6.3962 0.997 2079108 Maybridge3_006917 CS(=O)(=O)/C(=C/c1cccn1c2ccc(cc2)C(F)(F)F)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K10 compound treatment 0.32 0.0218 1.76 0.33 0.0327 2.97 3.3401 0.9687 1209810 Maybridge3_006918 CSCCn1c(C)c(cc1C(C)(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K11 compound treatment 0.316 0.0178 1.43 0.317 0.0197 1.79 2.2779 0.9941 2079109 Maybridge3_006919 OC(=O)C1CN(C(=O)C1)c2ccc(OC(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K12 compound treatment 0.32 0.0218 1.76 0.316 0.0187 1.7 2.4415 0.9998 2079110 Maybridge3_006920 Cc1nc(cs1)c2ccc(C#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K13 compound treatment 0.313 0.0148 1.19 0.314 0.0167 1.51 1.9145 0.993 2079111 Maybridge3_006921 Nc1ccccc1SCc2noc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K14 compound treatment 0.329 0.0308 2.48 0.321 0.0237 2.15 3.2749 0.9975 1519350 Maybridge3_006922 CC(C)(C)S(=O)(=O)Cc1nc(cs1)c2ccc(F)c(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K15 compound treatment 0.317 0.0188 1.51 0.319 0.0217 1.97 2.4632 0.9916 2079112 Maybridge3_006923 Fc1cc(F)cc(CC(=O)n2nccc2c3cccs3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K16 compound treatment 0.324 0.0258 2.08 0.333 0.0357 3.24 3.7604 0.977 2079113 Maybridge3_006924 Cc1c(sc2ccccc12)c3csc(n3)c4ccno4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K17 compound treatment 0.362 0.0638 5.14 0.375 0.0777 7.05 8.6199 0.9879 2079114 Maybridge3_006925 O=S(=O)(/C(=C\c1ccccc1N2CCN(Cc3ccccc3)CC2)/C#N)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K18 compound treatment 0.323 0.0248 2.0 0.321 0.0237 2.15 2.9332 0.9993 2079115 Maybridge3_006926 Cc1noc(C)c1c2nc(no2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K19 compound treatment 0.314 0.0158 1.27 0.313 0.0157 1.42 1.9073 0.9984 1626038 Maybridge3_006927 CN(C)c1ccc(cc1)C2CC(=O)C=C(C2)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K20 compound treatment 0.313 0.0148 1.19 0.316 0.0187 1.7 2.0429 0.9852 1293364 Maybridge3_006928 CCCc1ccc(cc1)c2nc(CS(=O)(=O)c3ccsc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K21 compound treatment 0.323 0.0248 2.0 0.319 0.0217 1.97 2.8049 1.0 2079116 Maybridge3_006929 CS(=O)(=O)/C(=C/c1ccc(OCc2cc(F)cc(F)c2)cc1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K22 compound treatment 0.321 0.0228 1.84 0.317 0.0197 1.79 2.5626 0.9999 1511680 Maybridge3_006930 COc1ccc(cc1)c2cc(N)n(n2)c3ccc(Cl)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K23 mock treatment 0.296 -0.00219 -0.18 0.296 -0.00131 -0.12 -0.2088 -0.9819 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 K24 positive control 0.095 -0.203 -16.36 0.096 -0.201 -18.27 -24.4909 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L01 compound treatment 0.34 0.0418 3.37 0.334 0.0367 3.33 4.7356 1.0 1481479 Maybridge3_006931 COc1ccc(cc1OC)c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L02 compound treatment 0.315 0.0168 1.35 0.316 0.0187 1.7 2.1568 0.9938 2079117 Maybridge3_006932 CSc1nnc([nH]1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L03 compound treatment 0.33 0.0318 2.56 0.328 0.0307 2.79 3.7811 0.9991 2079118 Maybridge3_006933 Nc1cc(nn1c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L04 compound treatment 0.333 0.0348 2.8 0.335 0.0377 3.42 4.4012 0.9951 2079119 Maybridge3_006934 CC(C)(C)C(=O)/C=C/1\C(=O)Nc2ccc(Br)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L05 compound treatment 0.314 0.0158 1.27 0.317 0.0197 1.79 2.164 0.9862 2079120 Maybridge3_006935 FC(F)(F)c1cc(no1)c2ccc(s2)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L06 compound treatment 0.315 0.0168 1.35 0.309 0.0117 1.06 1.7075 0.9927 2079121 Maybridge3_006936 CCOC(=O)/C=C(/Nc1ccccc1SC)\c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L07 compound treatment 0.334 0.0358 2.88 0.33 0.0327 2.97 4.1372 0.9999 1195723 Maybridge3_006937 Cc1oc(cc1C(=O)Nc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L08 compound treatment 0.322 0.0238 1.92 0.32 0.0227 2.06 2.8121 0.9994 2079122 Maybridge3_006938 CN(C)C(=O)Oc1ccc(cc1)C2SCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L09 compound treatment 0.318 0.0198 1.6 0.323 0.0257 2.33 2.7769 0.9829 1343741 Maybridge3_006939 COc1ccc2[nH]c(cc2c1)C(=O)Nc3ncc(C)cc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L10 compound treatment 0.323 0.0248 2.0 0.32 0.0227 2.06 2.869 0.9999 2079123 Maybridge3_006940 FC(F)(F)c1cc(c2cccs2)n3ncnc3n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L11 compound treatment 0.32 0.0218 1.76 0.321 0.0237 2.15 2.7624 0.995 1356495 Maybridge3_006941 Clc1ccc(OCc2nc(CSc3ccccn3)no2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L12 compound treatment 0.313 0.0148 1.19 0.311 0.0137 1.24 1.722 0.9998 2079124 Maybridge3_006942 Cc1cc(CSCc2ccc(Cl)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L13 compound treatment 0.326 0.0278 2.24 0.32 0.0227 2.06 3.0399 0.9991 2079125 Maybridge3_006943 Cn1nc(NC(=O)C(C)(C)C)c2c(F)cccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L14 compound treatment 0.303 0.00481 0.39 0.306 0.00869 0.79 0.8316 0.9465 2079126 Maybridge3_006944 CC(C)Sc1nnc(O)n1C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L15 compound treatment 0.328 0.0298 2.4 0.32 0.0227 2.06 3.1537 0.9971 1590850 Maybridge3_006945 CS(=O)(=O)Nc1ccccc1c2nnc(Cc3cc(F)cc(F)c3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L16 compound treatment 0.317 0.0188 1.51 0.317 0.0197 1.79 2.3348 0.9966 1070425 Maybridge3_006946 CSc1nnc(C)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L17 compound treatment 0.325 0.0268 2.16 0.326 0.0287 2.6 3.368 0.9957 2079127 Maybridge3_006947 CCOC(=O)c1cnn(c1C(C)C)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L18 compound treatment 0.313 0.0148 1.19 0.312 0.0147 1.33 1.7862 0.9985 2079128 Maybridge3_006948 Clc1ccccc1OCc2nnc(o2)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L19 compound treatment 0.321 0.0228 1.84 0.318 0.0207 1.88 2.6268 0.9999 2079129 Maybridge3_006949 CN/C(=N\O)/c1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L20 compound treatment 0.33 0.0318 2.56 0.324 0.0267 2.42 3.5244 0.9996 2079130 Maybridge3_006950 FC(F)(F)c1ccc(cc1)c2nnc(o2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L21 compound treatment 0.313 0.0148 1.19 0.314 0.0167 1.51 1.9145 0.993 2079131 Maybridge3_006951 COc1c(Br)cc(cc1Br)c2noc(CSC)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L22 compound treatment 0.323 0.0248 2.0 0.321 0.0237 2.15 2.9332 0.9993 2079132 Maybridge3_006952 Cc1ccc(cc1)S(=O)(=O)Cc2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L23 mock treatment 0.298 -1.88E-4 -0.02 0.298 6.88E-4 0.06 0.0335 0.521 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 L24 positive control 0.095 -0.203 -16.36 0.095 -0.202 -18.36 -24.5551 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M01 compound treatment 0.319 0.0208 1.68 0.313 0.0157 1.42 2.192 0.9967 1224935 Maybridge3_006953 Fc1ccc(C(=O)C2CCN(CC2)S(=O)(=O)c3ccc(F)cc3F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M02 compound treatment 0.312 0.0138 1.11 0.305 0.00769 0.7 1.2799 0.9748 2079133 Maybridge3_006954 Cc1cc(C)c([nH]1)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M03 compound treatment 0.314 0.0158 1.27 0.312 0.0147 1.33 1.8431 0.9997 1365276 Maybridge3_006955 COc1ccc(NC(=O)c2ccc(s2)C(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M04 compound treatment 0.319 0.0208 1.68 0.32 0.0227 2.06 2.6413 0.9948 2079134 Maybridge3_006956 CCOC(=O)c1cc(oc1C)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M05 compound treatment 0.315 0.0168 1.35 0.314 0.0167 1.51 2.0284 0.9984 2079135 Maybridge3_006957 Cc1noc(C)c1C(=O)N2CCSCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M06 compound treatment 0.314 0.0158 1.27 0.313 0.0157 1.42 1.9073 0.9984 1565599 Maybridge3_006958 O=S(=O)(NCc1ccc2OCCc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M07 compound treatment 0.322 0.0238 1.92 0.311 0.0137 1.24 2.2344 0.9779 2079136 Maybridge3_006959 Cc1noc(C)c1c2nnc(o2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M08 compound treatment 0.322 0.0238 1.92 0.321 0.0237 2.15 2.8763 0.9984 1453612 Maybridge3_006960 O=C(Nc1ccccc1)c2csc(n2)c3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M09 compound treatment 0.343 0.0448 3.61 0.342 0.0447 4.06 5.4199 0.9983 2079137 Maybridge3_006961 CC(C)(C)SCCC(=O)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M10 compound treatment 0.337 0.0388 3.13 0.332 0.0347 3.15 4.4364 1.0 1706379 Maybridge3_006962 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M11 compound treatment 0.319 0.0208 1.68 0.318 0.0207 1.88 2.5129 0.9984 1254405 Maybridge3_006963 OC(=O)C1CN(C(=O)C1)c2ccc(cc2)c3csnn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M12 compound treatment 0.313 0.0148 1.19 0.368 0.0707 6.42 5.3805 0.8244 2079138 Maybridge3_006964 Fc1cccc(c1)c2csc(n2)c3ccc(cc3)c4csnn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M13 compound treatment 0.382 0.0838 6.75 0.371 0.0737 6.69 9.502 1.0 1359109 Maybridge3_006965 O=C(c1ccccc1)c2cccc3CCNc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M14 compound treatment 0.322 0.0238 1.92 0.326 0.0287 2.6 3.1972 0.9887 1584516 Maybridge3_006966 CC(C)(C)S(=O)(=O)Cc1nc(cs1)c2ccc3OCCCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M15 compound treatment 0.451 0.153 12.31 0.457 0.16 14.5 18.9508 0.9967 2079139 Maybridge3_006967 COC(=O)c1cc(/C=C/2\C(=O)Nc3ccccc23)cn1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M16 compound treatment 0.31 0.0118 0.95 0.316 0.0187 1.7 1.8721 0.9626 1167043 Maybridge3_006968 N#Cc1ccc(cc1)c2csc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M17 compound treatment 0.318 0.0198 1.6 0.315 0.0177 1.61 2.2634 1.0 2079140 Maybridge3_006969 Cn1nc(cc1C(C)(C)C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M18 compound treatment 0.321 0.0228 1.84 0.319 0.0217 1.97 2.691 0.9994 1598801 Maybridge3_006970 C1CC(C1)c2nc(no2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M19 compound treatment 0.33 0.0318 2.56 0.327 0.0297 2.69 3.7169 0.9997 1448175 Maybridge3_006971 CN(C)c1ccc(cc1)C2CC(=O)C=C(C2)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M20 compound treatment 0.305 0.00681 0.55 0.306 0.00869 0.79 0.9455 0.9843 1674610 Maybridge3_006972 COc1ccc(Br)c(c1)c2nc(CS(=O)(=O)c3ccsc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M21 compound treatment 0.344 0.0458 3.69 0.346 0.0487 4.42 5.7336 0.996 1706871 Maybridge3_006973 COc1ccc(cc1)c2csc(CN3CCN(CC3)c4ccccc4OC)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M22 compound treatment 0.339 0.0408 3.29 0.333 0.0357 3.24 4.6145 1.0 2079141 Maybridge3_006974 COc1ccc(cc1OC)c2nc(no2)c3cccc(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M23 mock treatment 0.296 -0.00219 -0.18 0.296 -0.00131 -0.12 -0.2088 -0.9819 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 M24 positive control 0.097 -0.201 -16.2 0.097 -0.2 -18.18 -24.3129 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N01 compound treatment 0.325 0.0268 2.16 0.324 0.0267 2.42 3.2397 0.9984 2079142 Maybridge3_006975 COc1ccc(Br)c(c1)c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N02 compound treatment 0.317 0.0188 1.51 0.313 0.0157 1.42 2.0781 0.9995 2079143 Maybridge3_006976 Clc1cc(Cl)cc(CN2CCSCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N03 compound treatment 0.314 0.0158 1.27 0.311 0.0137 1.24 1.7789 0.9999 1654415 Maybridge3_006977 Fc1ccc(cc1)n2nc(cc2NC(=O)C3CCC3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N04 compound treatment 0.315 0.0168 1.35 0.311 0.0137 1.24 1.8359 0.9991 2079144 Maybridge3_006978 Fc1ccccc1c2nnc(SCC(=O)c3ccccc3)[nH]2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N05 compound treatment 0.311 0.0128 1.03 0.313 0.0157 1.42 1.7365 0.9875 1146074 Maybridge3_006979 CSc1[nH]nc(c1C#N)c2cc(oc2C)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N06 compound treatment 0.327 0.0288 2.32 0.322 0.0247 2.24 3.2252 0.9998 1531789 Maybridge3_006980 CC(C)(C)C(=O)Nc1ccc(Cl)cc1c2noc(n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N07 compound treatment 0.335 0.0368 2.96 0.331 0.0337 3.06 4.2584 0.9999 2079145 Maybridge3_006981 COC(=O)C1SCCN1C(=O)c2cc(oc2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N08 compound treatment 0.331 0.0328 2.64 0.328 0.0307 2.79 3.8381 0.9997 2079146 Maybridge3_006982 CN/C(=C(\C(=O)OC)/C(=O)c1ccc(Cl)cc1)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N09 compound treatment 0.314 0.0158 1.27 0.327 0.0297 2.69 2.8059 0.9414 1478084 Maybridge3_006983 Cc1oc(cc1C(=O)Nc2cc(C)nc(C)n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N10 compound treatment 0.33 0.0318 2.56 0.321 0.0237 2.15 3.3318 0.9962 2079147 Maybridge3_006984 CN/C(=C(\C(=O)OC)/C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N11 compound treatment 0.334 0.0358 2.88 0.335 0.0377 3.42 4.4582 0.9964 2079148 Maybridge3_006985 Cc1cc(C(=O)n2cc(C)c(n2)c3cccs3)c(C)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N12 compound treatment 0.313 0.0148 1.19 0.314 0.0167 1.51 1.9145 0.993 2079149 Maybridge3_006986 Cc1cc(CSc2cc(C)c(Cl)cc2Cl)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N13 compound treatment 0.337 0.0388 3.13 0.333 0.0357 3.24 4.5006 0.9998 2079150 Maybridge3_006987 Cc1c(cnn1c2ccccc2)c3ccnn3C(=O)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N14 compound treatment 0.328 0.0298 2.4 0.324 0.0267 2.42 3.4105 1.0 2079151 Maybridge3_006988 CN/C(=C(/C(=O)OC)\C(=O)c1ccc(cc1)C(F)(F)F)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N15 compound treatment 0.318 0.0198 1.6 0.319 0.0217 1.97 2.5202 0.9946 2079152 Maybridge3_006989 COC(=O)c1c(C)oc(C)c1S(=O)(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N16 compound treatment 0.317 0.0188 1.51 0.319 0.0217 1.97 2.4632 0.9916 2079153 Maybridge3_006990 CCOC(=O)CSc1nnc(O)n1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N17 compound treatment 0.314 0.0158 1.27 0.316 0.0187 1.7 2.0998 0.99 2079154 Maybridge3_006991 COC(=O)c1ccc(n1C)S(=O)(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N18 compound treatment 0.324 0.0258 2.08 0.326 0.0287 2.6 3.3111 0.9938 2079155 Maybridge3_006992 FC(F)(F)c1ccc(cc1)C(=O)NC(=S)SCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N19 compound treatment 0.312 0.0138 1.11 0.317 0.0197 1.79 2.0501 0.974 2079156 Maybridge3_006993 CSc1nnc([nH]1)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N20 compound treatment 0.318 0.0198 1.6 0.317 0.0197 1.79 2.3918 0.9984 2079157 Maybridge3_006994 Clc1ccc(cc1)c2nnc(o2)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N21 compound treatment 0.32 0.0218 1.76 0.32 0.0227 2.06 2.6982 0.9969 2079158 Maybridge3_006995 O/N=C(\C#N)/c1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N22 compound treatment 0.322 0.0238 1.92 0.32 0.0227 2.06 2.8121 0.9994 2079159 Maybridge3_006996 CCCS(=O)(=O)Cc1nnc(o1)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N23 mock treatment 0.3 0.00181 0.15 0.299 0.00169 0.15 0.2115 0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 N24 positive control 0.097 -0.201 -16.2 0.097 -0.2 -18.18 -24.3129 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O01 compound treatment 0.333 0.0348 2.8 0.33 0.0327 2.97 4.0803 0.9996 2079160 Maybridge3_006997 Clc1ccc(c2cc[nH]n2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O02 compound treatment 0.325 0.0268 2.16 0.325 0.0277 2.51 3.3039 0.9971 1050829 Maybridge3_006998 Clc1cccc(c1)c2nnc(o2)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O03 compound treatment 0.323 0.0248 2.0 0.316 0.0187 1.7 2.6123 0.9967 2079161 Maybridge3_006999 Cc1noc(C)c1S(=O)(=O)NCc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O04 compound treatment 0.325 0.0268 2.16 0.32 0.0227 2.06 2.9829 0.9997 1704347 Maybridge3_007000 Cc1oc(cc1C(=O)N)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O05 compound treatment 0.324 0.0258 2.08 0.321 0.0237 2.15 2.9902 0.9999 2079162 Maybridge3_007001 COC(=O)c1ccc(CSc2ncccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O06 compound treatment 0.321 0.0228 1.84 0.319 0.0217 1.97 2.691 0.9994 1398279 Maybridge3_007002 O=S(=O)(NCc1ccc2OCCc2c1)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O07 compound treatment 0.333 0.0348 2.8 0.331 0.0337 3.06 4.1445 0.9991 2079163 Maybridge3_007003 Cc1noc(C)c1c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O08 compound treatment 0.333 0.0348 2.8 0.333 0.0357 3.24 4.2729 0.9974 1498956 Maybridge3_007004 COC(=O)c1sc(c(C#N)c1c2cc(oc2C)C(C)(C)C)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O09 compound treatment 0.328 0.0298 2.4 0.326 0.0287 2.6 3.5389 0.9992 2079164 Maybridge3_007005 OC(=O)CCCC(=O)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O10 compound treatment 0.348 0.0498 4.01 0.348 0.0507 4.6 6.0897 0.9977 1737935 Maybridge3_007006 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3ccc(N)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O11 compound treatment 0.318 0.0198 1.6 0.317 0.0197 1.79 2.3918 0.9984 1322897 Maybridge3_007007 CSc1ccccc1N2CC(CC2=O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O12 compound treatment 0.319 0.0208 1.68 0.321 0.0237 2.15 2.7055 0.9924 1180310 Maybridge3_007008 CSCCn1c(C)c(cc1c2ccccc2)C(=O)NCc3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O13 compound treatment 0.332 0.0338 2.72 0.331 0.0337 3.06 4.0875 0.9983 1635498 Maybridge3_007009 Cc1cc(C)c(C(=O)C2CCN(CC2)C(=O)c3cccs3)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O14 compound treatment 0.328 0.0298 2.4 0.326 0.0287 2.6 3.5389 0.9992 1454200 Maybridge3_007010 Cc1ccc(c2csc(CS(=O)(=O)C(C)(C)C)n2)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O15 compound treatment 0.331 0.0328 2.64 0.333 0.0357 3.24 4.159 0.9949 2079165 Maybridge3_007011 FC(F)(F)Oc1ccc(/C=C/C(=O)NCc2ccco2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O16 compound treatment 0.32 0.0218 1.76 0.321 0.0237 2.15 2.7624 0.995 2079166 Maybridge3_007012 FC(F)(F)c1ccc(cc1)c2csc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O17 compound treatment 0.326 0.0278 2.24 0.322 0.0247 2.24 3.1682 1.0 1550633 Maybridge3_007013 Clc1cccc(c1)N2CCN(CC#N)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O18 compound treatment 0.319 0.0208 1.68 0.319 0.0217 1.97 2.5771 0.9968 2079167 Maybridge3_007014 CCCc1ccc(cc1)c2nc(no2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O19 compound treatment 0.321 0.0228 1.84 0.33 0.0327 2.97 3.397 0.9734 2079168 Maybridge3_007015 Brc1ccc(cc1)c2csc(Nc3ccncc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O20 compound treatment 0.355 0.0568 4.57 0.312 0.0147 1.33 4.1777 0.8767 2079169 Maybridge3_007016 CCCc1ccc(cc1)c2nc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O21 compound treatment 0.323 0.0248 2.0 0.325 0.0277 2.51 3.19 0.9935 1357939 Maybridge3_007017 OC(=O)CCc1c([nH]c2cc(Cl)cc(Cl)c12)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O22 compound treatment 0.327 0.0288 2.32 0.325 0.0277 2.51 3.4177 0.9992 2079170 Maybridge3_007018 Cc1cccc(c1)c2noc(n2)c3ccc(F)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O23 mock treatment 0.305 0.00681 0.55 0.304 0.00669 0.61 0.8171 0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 O24 positive control 0.097 -0.201 -16.2 0.098 -0.199 -18.09 -24.2487 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P01 compound treatment 0.325 0.0268 2.16 0.324 0.0267 2.42 3.2397 0.9984 2079171 Maybridge3_007019 CCn1nc(C)c(Br)c1c2nc(no2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P02 compound treatment 0.322 0.0238 1.92 0.321 0.0237 2.15 2.8763 0.9984 2079172 Maybridge3_007020 CSc1nc(nn1C(=O)N(C)C)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P03 compound treatment 0.324 0.0258 2.08 0.324 0.0267 2.42 3.1827 0.9971 1488865 Maybridge3_007021 Nc1cc(nn1c2ccc(cc2)S(=O)(=O)N)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P04 compound treatment 0.323 0.0248 2.0 0.324 0.0267 2.42 3.1258 0.9954 1098512 Maybridge3_007022 CCOC(=O)Cc1csc2nc(nn12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P05 compound treatment 0.35 0.0518 4.17 0.348 0.0507 4.6 6.2036 0.9988 1380119 Maybridge3_007023 Cc1oc(cc1C(=O)N2CCCC2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P06 compound treatment 0.319 0.0208 1.68 0.317 0.0197 1.79 2.4487 0.9995 2079173 Maybridge3_007024 CC(C)(C)c1ccc(OC/C(=N/O)/N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P07 compound treatment 0.347 0.0488 3.93 0.361 0.0637 5.78 6.8672 0.9823 1273209 Maybridge3_007025 COc1ccc2[nH]c(cc2c1)C(=O)Nc3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P08 compound treatment 0.338 0.0398 3.21 0.337 0.0397 3.6 4.8143 0.9983 2079174 Maybridge3_007026 CN/C(=C(\C(=O)OC)/C(=O)c1cccs1)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P09 compound treatment 0.316 0.0178 1.43 0.315 0.0177 1.61 2.1495 0.9984 1399294 Maybridge3_007027 COc1ccc(NC(=O)c2cc(oc2C)C(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P10 compound treatment 0.336 0.0378 3.04 0.333 0.0357 3.24 4.4437 0.9995 2079175 Maybridge3_007028 CCN(CC)C(=O)Oc1nnc(SC(C)C)n1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P11 compound treatment 0.332 0.0338 2.72 0.337 0.0397 3.6 4.4727 0.9905 1684700 Maybridge3_007029 Cc1ccc(cc1)C(=O)Nc2ccc3[nH]cc(C#N)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P12 compound treatment 0.315 0.0168 1.35 0.315 0.0177 1.61 2.0926 0.9964 2079176 Maybridge3_007030 NC(=N)c1ccc(cc1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P13 compound treatment 0.312 0.0138 1.11 0.314 0.0167 1.51 1.8576 0.9885 2079177 Maybridge3_007031 FC(F)(F)c1cc(n[nH]1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P14 compound treatment 0.316 0.0178 1.43 0.316 0.0187 1.7 2.2137 0.9965 2079178 Maybridge3_007032 N/C(=N\O)/c1ccc(OCc2ccccc2F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P15 compound treatment 0.318 0.0198 1.6 0.32 0.0227 2.06 2.5843 0.992 2079179 Maybridge3_007033 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P16 compound treatment 0.321 0.0228 1.84 0.321 0.0237 2.15 2.8193 0.9969 2079180 Maybridge3_007034 CN/C(=C(\C(=O)OC)/C(=O)c1snnc1C)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P17 compound treatment 0.321 0.0228 1.84 0.317 0.0197 1.79 2.5626 0.9999 1583722 Maybridge3_007035 COC(=O)c1ccc(n1C)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P18 compound treatment 0.325 0.0268 2.16 0.321 0.0237 2.15 3.0471 1.0 2079181 Maybridge3_007036 CCOC(=O)Cn1nnc(CSc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P19 compound treatment 0.318 0.0198 1.6 0.316 0.0187 1.7 2.3276 0.9995 2079182 Maybridge3_007037 C=CCSc1nnc([nH]1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P20 compound treatment 0.328 0.0298 2.4 0.328 0.0307 2.79 3.6672 0.9973 2079183 Maybridge3_007038 CCOC(=O)c1sc(CS(=O)(=O)c2ccc(Cl)cc2)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P21 compound treatment 0.323 0.0248 2.0 0.322 0.0247 2.24 2.9974 0.9984 2079184 Maybridge3_007039 NC(=N)Cc1c(Cl)cccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P22 compound treatment 0.335 0.0368 2.96 0.332 0.0347 3.15 4.3226 0.9995 1157573 Maybridge3_007040 CCCS(=O)(=O)Cc1nnc(o1)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P23 mock treatment 0.304 0.00581 0.47 0.305 0.00769 0.7 0.8244 0.9811 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1450 P24 positive control 0.1 -0.198 -15.96 0.098 -0.199 -18.09 -24.0778 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A01 compound treatment 0.31 0.00244 0.2 0.314 0.001 0.09 0.203 0.9386 1423117 Maybridge3_007041 CCCS(=O)(=O)Cc1nnc(o1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A02 compound treatment 0.306 -0.00156 -0.13 0.311 -0.002 -0.18 -0.2173 -0.984 2079185 Maybridge3_007042 CCOC(=O)c1csc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A03 compound treatment 0.31 0.00244 0.2 0.312 -0.001 -0.09 0.0746 0.345 1246303 Maybridge3_007043 CCC(=O)Nc1c(C#N)c(C)c(C)n1Cc2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A04 compound treatment 0.307 -5.63E-4 -0.05 0.311 -0.002 -0.18 -0.1604 -0.8573 2079186 Maybridge3_007044 Clc1ccc(cc1)c2nc(no2)c3[nH]ncc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A05 compound treatment 0.307 -5.63E-4 -0.05 0.319 0.006 0.54 0.3531 0.6461 2079187 Maybridge3_007045 CCOC(=O)c1csc(COc2ccc(cc2)C3SCCS3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A06 compound treatment 0.301 -0.00656 -0.53 0.303 -0.01 -0.91 -1.0155 -0.9669 2079188 Maybridge3_007046 FC(F)(F)c1cnc(Oc2ccc(C#N)cc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A07 compound treatment 0.304 -0.00356 -0.29 0.31 -0.003 -0.27 -0.3954 -0.9997 2079189 Maybridge3_007047 Cc1nc(CSc2nnc(O)n2c3ccccc3)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A08 compound treatment 0.298 -0.00956 -0.77 0.301 -0.012 -1.09 -1.3147 -0.9856 1158898 Maybridge3_007048 O=c1oc2ccccc2n1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A09 compound treatment 0.294 -0.0136 -1.09 0.309 -0.004 -0.36 -1.029 -0.8941 1193869 Maybridge3_007049 CSc1nnc(SCc2nc(cs2)c3ccc(Cl)cc3)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A10 compound treatment 0.298 -0.00956 -0.77 0.302 -0.011 -1.0 -1.2505 -0.9918 2079190 Maybridge3_007050 FC(F)(F)c1ccc(Oc2ccc(CC#N)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A11 compound treatment 0.3 -0.00756 -0.61 0.308 -0.005 -0.45 -0.7515 -0.9895 2079191 Maybridge3_007051 COC(=O)c1c(C)noc1c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A12 compound treatment 0.305 -0.00256 -0.21 0.312 -0.001 -0.09 -0.2101 -0.932 2079192 Maybridge3_007052 FC(F)(F)c1nnc(Sc2ncccc2C(F)(F)F)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A13 compound treatment 0.319 0.0114 0.92 0.327 0.014 1.27 1.5499 0.9875 2079193 Maybridge3_007053 CC(C)c1ccc(NC(=O)CSc2nnc(c3csc(C)n3)n2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A14 compound treatment 0.305 -0.00256 -0.21 0.314 0.001 0.09 -0.0817 -0.3625 2079194 Maybridge3_007054 CCc1nnc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A15 compound treatment 0.302 -0.00556 -0.45 0.311 -0.002 -0.18 -0.4451 -0.9209 2079195 Maybridge3_007055 CCOC(=O)CSc1nc2cc(ccc2[nH]1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A16 compound treatment 0.304 -0.00356 -0.29 0.312 -0.001 -0.09 -0.267 -0.8875 2079196 Maybridge3_007056 Oc1cc(nc(n1)c2ccccc2OC(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A17 compound treatment 0.318 0.0104 0.84 0.324 0.011 1.0 1.3004 0.9963 2079197 Maybridge3_007057 CCOC(=O)c1sc(nc1OC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A18 compound treatment 0.302 -0.00556 -0.45 0.309 -0.004 -0.36 -0.5735 -0.9946 2079198 Maybridge3_007058 Fc1ccc(cc1)C(=O)n2nccc2c3csc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A19 compound treatment 0.334 0.0264 2.13 0.326 0.013 1.18 2.3398 0.9613 2079199 Maybridge3_007059 Cc1nc(COc2ccccc2Cl)sc1c3ccnc(N)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A20 compound treatment 0.305 -0.00256 -0.21 0.31 -0.003 -0.27 -0.3385 -0.9906 2079200 Maybridge3_007060 Cc1cc(no1)c2nnnn2c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A21 compound treatment 0.32 0.0124 1.0 0.327 0.014 1.27 1.6068 0.9931 1421657 Maybridge3_007061 CCn1nc(C)cc1c2nnc(SCC(=O)c3ccc(C)cc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A22 compound treatment 0.301 -0.00656 -0.53 0.309 -0.004 -0.36 -0.6304 -0.9832 2079201 Maybridge3_007062 Clc1cc(Cl)cc(OC(=O)c2ccno2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A23 mock treatment 0.295 -0.0126 -1.01 0.305 -0.008 -0.73 -1.2288 -0.9868 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 A24 positive control 0.088 -0.22 -17.68 0.085 -0.228 -20.7 -27.1363 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B01 compound treatment 0.314 0.00644 0.52 0.323 0.01 0.91 1.0084 0.9647 2079202 Maybridge3_007063 FC(F)(F)c1cccnc1SCC(=O)Nc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B02 compound treatment 0.318 0.0104 0.84 0.328 0.015 1.36 1.5571 0.9731 2079203 Maybridge3_007064 CCOC(=O)c1cnc(nc1Oc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B03 compound treatment 0.321 0.0134 1.08 0.324 0.011 1.0 1.4712 0.9992 2079204 Maybridge3_007065 Cc1n[nH]c(C)c1Sc2nnc(n2C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B04 compound treatment 0.324 0.0164 1.32 0.328 0.015 1.36 1.8987 0.9999 2079205 Maybridge3_007066 Clc1ccc(cc1)S(=O)(=O)n2nccc2c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B05 compound treatment 0.318 0.0104 0.84 0.316 0.003 0.27 0.7869 0.8906 1378139 Maybridge3_007067 Cc1ccc(Oc2c(C)nc(C)nc2O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B06 compound treatment 0.316 0.00844 0.68 0.319 0.006 0.54 0.8655 0.994 2079206 Maybridge3_007068 Cc1onc(c1c2ccnc(N)n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B07 compound treatment 0.322 0.0144 1.16 0.332 0.019 1.72 2.0416 0.9816 2079207 Maybridge3_007069 CCn1nc(cc1C(=O)N(C)C)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B08 compound treatment 0.307 -5.63E-4 -0.05 0.316 0.003 0.27 0.1605 0.5815 1480615 Maybridge3_007070 Cc1nn(C(=O)c2ccccc2)c(C)c1Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B09 compound treatment 0.311 0.00344 0.28 0.321 0.008 0.73 0.7092 0.9126 2079208 Maybridge3_007071 O/N=C/c1ccnc(SCc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B10 compound treatment 0.318 0.0104 0.84 0.327 0.014 1.27 1.4929 0.9799 2079209 Maybridge3_007072 Cc1noc2ncnc(SCC(=O)c3ccc(Cl)cc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B11 compound treatment 0.34 0.0324 2.61 0.364 0.051 4.63 5.1205 0.9633 1456200 Maybridge3_007073 COC(OC)c1ccc2c(N)c(sc2n1)C(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B12 compound treatment 0.346 0.0384 3.1 0.359 0.046 4.18 5.1412 0.9891 2079210 Maybridge3_007074 Cc1noc(N)c1c2nc(cs2)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B13 compound treatment 0.33 0.0224 1.81 0.337 0.024 2.18 2.8181 0.9957 2079211 Maybridge3_007075 Cc1nn(c(C)c1Sc2ncccn2)S(=O)(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B14 compound treatment 0.316 0.00844 0.68 0.321 0.008 0.73 0.9939 0.9994 2079212 Maybridge3_007076 COC(=O)c1cc(=O)n2c(nnc2s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B15 compound treatment 0.315 0.00744 0.6 0.324 0.011 1.0 1.1295 0.9701 2079213 Maybridge3_007077 CSc1nc(/C=N/O)ccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B16 compound treatment 0.314 0.00644 0.52 0.325 0.012 1.09 1.1368 0.9424 2079214 Maybridge3_007078 Cc1nc(COc2ccccc2Cl)nc(O)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B17 compound treatment 0.321 0.0134 1.08 0.324 0.011 1.0 1.4712 0.9992 1409070 Maybridge3_007079 COCc1cc(OC)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B18 compound treatment 0.316 0.00844 0.68 0.328 0.015 1.36 1.4432 0.9484 2079215 Maybridge3_007080 FC(F)(F)c1ccc(nc1)c2nnc(o2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B19 compound treatment 0.321 0.0134 1.08 0.328 0.015 1.36 1.7279 0.9935 1262929 Maybridge3_007081 CCOC(=O)c1cc(on1)c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B20 compound treatment 0.321 0.0134 1.08 0.328 0.015 1.36 1.7279 0.9935 2079216 Maybridge3_007082 Cc1n[nH]c(C)c1Sc2nnnn2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B21 compound treatment 0.322 0.0144 1.16 0.329 0.016 1.45 1.849 0.9939 2079217 Maybridge3_007083 CCOC(=O)c1cnc(nc1Nc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B22 compound treatment 0.316 0.00844 0.68 0.32 0.007 0.64 0.9297 0.9994 2079218 Maybridge3_007084 Cc1ccc(cc1)c2nc(no2)c3ccc(OCC(F)(F)F)nc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B23 mock treatment 0.308 4.37E-4 0.04 0.318 0.005 0.45 0.3458 0.7597 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 B24 positive control 0.088 -0.22 -17.68 0.086 -0.227 -20.61 -27.0721 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C01 compound treatment 0.319 0.0114 0.92 0.325 0.012 1.09 1.4215 0.9965 2079219 Maybridge3_007085 CCOC(=O)c1sc(SCC(=O)c2ccc(Cl)cc2)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C02 compound treatment 0.322 0.0144 1.16 0.335 0.022 2.0 2.2342 0.9669 2079220 Maybridge3_007086 Cc1nc(sc1c2nnc(o2)C3CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C03 compound treatment 0.302 -0.00556 -0.45 0.304 -0.009 -0.82 -0.8944 -0.96 2079221 Maybridge3_007087 Cc1c(C)n(Cc2cccs2)c(c1C#N)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C04 compound treatment 0.319 0.0114 0.92 0.32 0.007 0.64 1.1006 0.9836 2079222 Maybridge3_007088 N/C(=N\O)/c1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C05 compound treatment 0.31 0.00244 0.2 0.319 0.006 0.54 0.5239 0.905 2079223 Maybridge3_007089 Cc1nc(CS(=O)(=O)c2ccc(Cl)cc2)sc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C06 compound treatment 0.315 0.00744 0.6 0.32 0.007 0.64 0.8728 0.9996 2079224 Maybridge3_007090 N/C(=N\O)/c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C07 compound treatment 0.306 -0.00156 -0.13 0.317 0.004 0.36 0.1678 0.4366 1682623 Maybridge3_007091 Cc1nc(CSc2nnc(O)n2Cc3ccccc3)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C08 compound treatment 0.329 0.0214 1.73 0.335 0.022 2.0 2.6327 0.9974 2079225 Maybridge3_007092 Cc1nc(sc1c2nnnn2c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C09 compound treatment 0.307 -5.63E-4 -0.05 0.318 0.005 0.45 0.2889 0.6334 1135678 Maybridge3_007093 CC(C)(C)c1csc(CS(=O)(=O)c2ccccn2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C10 compound treatment 0.329 0.0214 1.73 0.345 0.032 2.9 3.2746 0.9691 2079226 Maybridge3_007094 FC(F)(F)c1cccnc1Oc2ccc(cc2)C3=NCCS3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C11 compound treatment 0.31 0.00244 0.2 0.316 0.003 0.27 0.3313 0.9871 2079227 Maybridge3_007095 CSc1nnc(c2csc(C)n2)n1c3cccc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C12 compound treatment 0.317 0.00944 0.76 0.32 0.007 0.64 0.9867 0.996 1361790 Maybridge3_007096 Cc1cc(NC(=O)c2ccno2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C13 compound treatment 0.304 -0.00356 -0.29 0.32 0.007 0.64 0.2464 0.3535 2079228 Maybridge3_007097 Cc1nc(cs1)c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C14 compound treatment 0.311 0.00344 0.28 0.324 0.011 1.0 0.9018 0.8703 2079229 Maybridge3_007098 Cc1cc(no1)C(=O)Oc2cc(C)c(Cl)c(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C15 compound treatment 0.332 0.0244 1.97 0.339 0.026 2.36 3.0603 0.9959 2079230 Maybridge3_007099 CCn1nc(C)cc1c2nnc(SC)n2c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C16 compound treatment 0.322 0.0144 1.16 0.324 0.011 1.0 1.5281 0.9971 2079231 Maybridge3_007100 CCOC(=O)c1noc(C)c1c2csc(COc3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C17 compound treatment 0.319 0.0114 0.92 0.322 0.009 0.82 1.2289 0.9982 1236652 Maybridge3_007101 CCn1c(SCC(=O)O)nc2cc(Cl)c(Cl)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C18 compound treatment 0.329 0.0214 1.73 0.33 0.017 1.54 2.3118 0.9984 2079232 Maybridge3_007102 Fc1ccc(c(F)c1)S(=O)(=O)n2nccc2c3csc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C19 compound treatment 0.375 0.0674 5.43 0.388 0.075 6.81 8.6538 0.9937 2079233 Maybridge3_007103 OC(=O)CC1SC(=NC1=O)c2cccc(c2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C20 compound treatment 0.327 0.0194 1.57 0.331 0.018 1.63 2.2621 0.9998 2079234 Maybridge3_007104 Cc1cc(no1)c2nnnn2c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C21 compound treatment 0.328 0.0204 1.65 0.335 0.022 2.0 2.5758 0.9954 2079235 Maybridge3_007105 CCn1nc(C)cc1c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C22 compound treatment 0.309 0.00144 0.12 0.325 0.012 1.09 0.8521 0.7779 2079236 Maybridge3_007106 CC(C)(C)c1cc(no1)C(=O)/C=C\2/NC(=O)CS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C23 mock treatment 0.303 -0.00456 -0.37 0.305 -0.008 -0.73 -0.7733 -0.9502 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 C24 positive control 0.093 -0.215 -17.28 0.088 -0.225 -20.42 -26.659 -0.9965 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D01 compound treatment 0.321 0.0134 1.08 0.326 0.013 1.18 1.5995 0.9991 2079237 Maybridge3_007107 FC(F)(F)c1cccnc1SCC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D02 compound treatment 0.32 0.0124 1.0 0.335 0.022 2.0 2.1203 0.9491 2079238 Maybridge3_007108 CC(=O)n1nccc1c2c(C)nc3ccccn23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D03 compound treatment 0.319 0.0114 0.92 0.326 0.013 1.18 1.4857 0.9925 2079239 Maybridge3_007109 Cn1c(SCc2cc(=O)[nH]c(n2)C(C)(C)C)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D04 compound treatment 0.313 0.00544 0.44 0.326 0.013 1.18 1.144 0.9089 2079240 Maybridge3_007110 Clc1cccc(NC(=O)n2nccc2c3cc(no3)c4ccccc4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D05 compound treatment 0.318 0.0104 0.84 0.334 0.021 1.91 1.9422 0.9323 2079241 Maybridge3_007111 Cc1nc(C)c(Oc2cccc(c2)C(F)(F)F)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D06 compound treatment 0.321 0.0134 1.08 0.339 0.026 2.36 2.434 0.9375 2079242 Maybridge3_007112 Cc1onc(c1c2ccnc(n2)c3ccc(Cl)cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D07 compound treatment 0.325 0.0174 1.4 0.332 0.019 1.72 2.2124 0.9948 2079243 Maybridge3_007113 CCn1nc(cc1C(=O)NC(C)C)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D08 compound treatment 0.323 0.0154 1.24 0.327 0.014 1.27 1.7776 0.9999 2079244 Maybridge3_007114 Cc1nn(C(=O)Nc2ccccc2)c(C)c1Oc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D09 compound treatment 0.338 0.0304 2.45 0.348 0.035 3.18 3.9796 0.9918 2079245 Maybridge3_007115 Cc1ccc(NC(=O)c2cc(on2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D10 compound treatment 0.311 0.00344 0.28 0.329 0.016 1.45 1.2227 0.827 2079246 Maybridge3_007116 Cc1noc2ncnc(SCc3ccc(C)cc3)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D11 compound treatment 0.36 0.0524 4.22 0.373 0.06 5.45 6.8369 0.9921 1241745 Maybridge3_007117 COC(OC)c1ccc2c(N)c(sc2n1)C(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D12 compound treatment 0.335 0.0274 2.21 0.344 0.031 2.81 3.5521 0.9928 1119305 Maybridge3_007118 CCOC(=O)c1sc2nc(nc(C)c2c1C)c3ccccc3OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D13 compound treatment 0.315 0.00744 0.6 0.322 0.009 0.82 1.0012 0.9884 2079247 Maybridge3_007119 COC(=O)c1ccc(O)c(CSc2ccc(Cl)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D14 compound treatment 0.317 0.00944 0.76 0.325 0.012 1.09 1.3076 0.9845 2079248 Maybridge3_007120 NC(=N)COc1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D15 compound treatment 0.318 0.0104 0.84 0.331 0.018 1.63 1.7497 0.9522 2079249 Maybridge3_007121 CC(=O)Nc1nc(C)c(Oc2cccc(c2)C(F)(F)F)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D16 compound treatment 0.321 0.0134 1.08 0.329 0.016 1.45 1.7921 0.9895 2079250 Maybridge3_007122 CCOC(=O)c1cnc(COc2ccccc2Cl)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D17 compound treatment 0.324 0.0164 1.32 0.334 0.021 1.91 2.2839 0.9841 2079251 Maybridge3_007123 C/C(=N\O)/c1csc(n1)c2ccno2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D18 compound treatment 0.318 0.0104 0.84 0.331 0.018 1.63 1.7497 0.9522 2079252 Maybridge3_007124 FC(F)(F)c1ccncc1c2nc(cs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D19 compound treatment 0.326 0.0184 1.48 0.332 0.019 1.72 2.2694 0.9972 1654323 Maybridge3_007125 Cc1nc2ccccn2c1c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D20 compound treatment 0.324 0.0164 1.32 0.332 0.019 1.72 2.1555 0.9915 2079253 Maybridge3_007126 CSC1=C(C#N)C(O)(NC(=N1)C(F)(F)F)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D21 compound treatment 0.316 0.00844 0.68 0.333 0.02 1.82 1.7641 0.9101 2079254 Maybridge3_007127 Cc1nc(nc(O)c1C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D22 compound treatment 0.351 0.0434 3.5 0.353 0.04 3.63 5.0408 0.9998 1166138 Maybridge3_007128 Nc1nc(COc2ccccc2Cl)ncc1S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D23 mock treatment 0.303 -0.00456 -0.37 0.314 0.001 0.09 -0.1956 -0.5169 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 D24 positive control 0.093 -0.215 -17.28 0.09 -0.223 -20.24 -26.5306 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E01 compound treatment 0.325 0.0174 1.4 0.332 0.019 1.72 2.2124 0.9948 1457391 Maybridge3_007129 CCn1nc(C)c(NC(=O)c2ccc(Cl)cc2)c1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E02 compound treatment 0.312 0.00444 0.36 0.327 0.014 1.27 1.1513 0.8721 2079255 Maybridge3_007130 FC(F)(F)c1ccc(SCC(=O)Nc2ccccc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E03 compound treatment 0.301 -0.00656 -0.53 0.313 0.0 0.0 -0.3737 -0.7071 2079256 Maybridge3_007131 Cc1c(C)n(CCCn2cccn2)c(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E04 compound treatment 0.335 0.0274 2.21 0.339 0.026 2.36 3.2311 0.9995 2079257 Maybridge3_007132 CSC(=CC(=O)c1sc(nc1C)c2cccs2)SC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E05 compound treatment 0.332 0.0244 1.97 0.339 0.026 2.36 3.0603 0.9959 2079258 Maybridge3_007133 CCOC(=O)Cc1csc(COc2ccc(cc2)C3SCCS3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E06 compound treatment 0.321 0.0134 1.08 0.321 0.008 0.73 1.2786 0.9812 1710811 Maybridge3_007134 Cc1c(C(=O)Oc2cc(Cl)cc(Cl)c2)n(C)oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E07 compound treatment 0.325 0.0174 1.4 0.328 0.015 1.36 1.9557 0.9999 2079259 Maybridge3_007135 Cc1nc(CSc2nnc([nH]2)C(F)(F)F)cs1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E08 compound treatment 0.318 0.0104 0.84 0.328 0.015 1.36 1.5571 0.9731 2079260 Maybridge3_007136 Cc1cc(NC(=O)c2ccc(Cl)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E09 compound treatment 0.315 0.00744 0.6 0.334 0.021 1.91 1.7714 0.8865 2079261 Maybridge3_007137 Cc1c(C)n(Cc2ccccc2Cl)c(N)c1S(=O)(=O)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E10 compound treatment 0.322 0.0144 1.16 0.327 0.014 1.27 1.7207 0.999 2079262 Maybridge3_007138 Cc1cc(C(=O)Oc2ccc(C)cc2)n(n1)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E11 compound treatment 0.316 0.00844 0.68 0.32 0.007 0.64 0.9297 0.9994 2079263 Maybridge3_007139 Cc1nc(cs1)c2ccc(cc2)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E12 compound treatment 0.324 0.0164 1.32 0.33 0.017 1.54 2.0271 0.9971 2079264 Maybridge3_007140 CN/C(=C(\C(=O)OC)/C(=O)c1cc(C)on1)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E13 compound treatment 0.314 0.00644 0.52 0.321 0.008 0.73 0.88 0.9863 2079265 Maybridge3_007141 Fc1cccc(Cl)c1CS(=O)(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E14 compound treatment 0.313 0.00544 0.44 0.322 0.009 0.82 0.8873 0.9573 2079266 Maybridge3_007142 Cc1cc(no1)c2onc(C)c2C(=O)Sc3c(Cl)cccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E15 compound treatment 0.339 0.0314 2.53 0.34 0.027 2.45 3.5231 0.9999 2079267 Maybridge3_007143 CCn1nc(C)cc1C(=O)Sc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E16 compound treatment 0.31 0.00244 0.2 0.325 0.012 1.09 0.909 0.8213 2079268 Maybridge3_007144 NNS(=O)(=O)c1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E17 compound treatment 0.31 0.00244 0.2 0.326 0.013 1.18 0.9732 0.8135 2079269 Maybridge3_007145 Cc1nc(sc1c2ccn[nH]2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E18 compound treatment 0.326 0.0184 1.48 0.341 0.028 2.54 2.847 0.9672 2079270 Maybridge3_007146 CCOC(=O)c1noc(C)c1c2csc(N)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E19 compound treatment 0.322 0.0144 1.16 0.329 0.016 1.45 1.849 0.9939 2079271 Maybridge3_007147 Cc1nc(cs1)c2noc(n2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E20 compound treatment 0.321 0.0134 1.08 0.336 0.023 2.09 2.2414 0.9532 2079272 Maybridge3_007148 Cc1cc(no1)c2nnnn2c3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E21 compound treatment 0.338 0.0304 2.45 0.351 0.038 3.45 4.1722 0.986 2079273 Maybridge3_007149 CCn1nc(C)cc1c2nnc(o2)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E22 compound treatment 0.287 -0.0206 -1.66 0.29 -0.023 -2.09 -2.6471 -0.9934 2079274 Maybridge3_007150 CCn1nc(C)cc1C(=O)Sc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E23 mock treatment 0.302 -0.00556 -0.45 0.309 -0.004 -0.36 -0.5735 -0.9946 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 E24 positive control 0.095 -0.213 -17.12 0.091 -0.222 -20.15 -26.3526 -0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F01 compound treatment 0.317 0.00944 0.76 0.325 0.012 1.09 1.3076 0.9845 2079275 Maybridge3_007151 FC(F)(F)c1cccc(c1)C(=O)CSc2ncccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F02 compound treatment 0.325 0.0174 1.4 0.336 0.023 2.09 2.4692 0.9814 2079276 Maybridge3_007152 CC(=O)n1nccc1c2cc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F03 compound treatment 0.322 0.0144 1.16 0.328 0.015 1.36 1.7849 0.9969 2079277 Maybridge3_007153 Cc1n[nH]c(C)c1Oc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F04 compound treatment 0.326 0.0184 1.48 0.338 0.025 2.27 2.6545 0.9789 1562665 Maybridge3_007154 CC(C)NC(=O)n1nccc1c2cc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F05 compound treatment 0.326 0.0184 1.48 0.332 0.019 1.72 2.2694 0.9972 2079278 Maybridge3_007155 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F06 compound treatment 0.327 0.0194 1.57 0.33 0.017 1.54 2.1979 1.0 2079279 Maybridge3_007156 Clc1ccc(cc1)c2nccc(n2)c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F07 compound treatment 0.331 0.0234 1.89 0.327 0.014 1.27 2.2331 0.9815 1320628 Maybridge3_007157 CCn1nc(cc1C(=O)Nc2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F08 compound treatment 0.31 0.00244 0.2 0.307 -0.006 -0.54 -0.2463 -0.4255 2079280 Maybridge3_007158 Cc1nn(c(C)c1Oc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F09 compound treatment 0.328 0.0204 1.65 0.35 0.037 3.36 3.5386 0.9461 2079281 Maybridge3_007159 Clc1ccc(NC(=O)c2cc(on2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F10 compound treatment 0.326 0.0184 1.48 0.332 0.019 1.72 2.2694 0.9972 2079282 Maybridge3_007160 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F11 compound treatment 0.355 0.0474 3.82 0.372 0.059 5.36 6.4881 0.9863 1269512 Maybridge3_007161 COC(OC)c1ccc2c(N)c(sc2n1)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F12 compound treatment 0.328 0.0204 1.65 0.33 0.017 1.54 2.2549 0.9995 2079283 Maybridge3_007162 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F13 compound treatment 0.304 -0.00356 -0.29 0.326 0.013 1.18 0.6316 0.5201 2079284 Maybridge3_007163 COC(=O)c1ccc(O)c(CSc2ccccn2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F14 compound treatment 0.323 0.0154 1.24 0.334 0.021 1.91 2.2269 0.9785 2079285 Maybridge3_007164 FC(F)(F)c1cccc(CS(=O)(=O)CC2=NC(=O)CS2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F15 compound treatment 0.319 0.0114 0.92 0.33 0.017 1.54 1.7424 0.9696 1491467 Maybridge3_007165 Cc1nc(N)nc(O)c1Oc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F16 compound treatment 0.351 0.0434 3.5 0.347 0.034 3.09 4.6557 0.9981 2079286 Maybridge3_007166 CCOC(=O)c1cc(on1)C(=O)CSc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F17 compound treatment 0.326 0.0184 1.48 0.332 0.019 1.72 2.2694 0.9972 2079287 Maybridge3_007167 CNc1cc(C)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F18 compound treatment 0.328 0.0204 1.65 0.34 0.027 2.45 2.8967 0.9812 2079288 Maybridge3_007168 FC(F)(F)COc1ccc(C#N)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F19 compound treatment 0.34 0.0324 2.61 0.352 0.039 3.54 4.3502 0.9888 1690234 Maybridge3_007169 CCOC(=O)c1nc(C)sc1c2ccnn2C(=O)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F20 compound treatment 0.334 0.0264 2.13 0.34 0.027 2.45 3.2384 0.9975 1662869 Maybridge3_007170 CCOC(=O)c1cnc(nc1Nc2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F21 compound treatment 0.324 0.0164 1.32 0.339 0.026 2.36 2.6048 0.9626 2079289 Maybridge3_007171 COc1cc(c(cn1)c2ncn[nH]2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F22 compound treatment 0.34 0.0324 2.61 0.354 0.041 3.72 4.4786 0.985 2079290 Maybridge3_007172 Cc1csc(n1)c2ccc(Oc3ccc(Cl)cc3)nc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F23 mock treatment 0.307 -5.63E-4 -0.05 0.311 -0.002 -0.18 -0.1604 -0.8573 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 F24 positive control 0.094 -0.214 -17.2 0.092 -0.221 -20.06 -26.3453 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G01 compound treatment 0.33 0.0224 1.81 0.33 0.017 1.54 2.3688 0.9969 2079291 Maybridge3_007173 FC(F)(F)c1ccc(cc1)c2nc(CS(=O)(=O)c3ccc(Cl)cc3)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G02 compound treatment 0.291 -0.0166 -1.33 0.298 -0.015 -1.36 -1.9059 -0.9999 2079292 Maybridge3_007174 FC(F)(F)c1ccc(cc1)C(=O)Sc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G03 compound treatment 0.313 0.00544 0.44 0.318 0.005 0.45 0.6305 0.9998 1662152 Maybridge3_007175 Cc1c(C)n(Cc2cccnc2)c(NC(=O)c3ccc(Cl)cc3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G04 compound treatment 0.295 -0.0126 -1.01 0.322 0.009 0.82 -0.1377 -0.1059 2079293 Maybridge3_007176 CSc1cc([nH]n1)c2sc(nc2C)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G05 compound treatment 0.3 -0.00756 -0.61 0.311 -0.002 -0.18 -0.559 -0.8796 1531001 Maybridge3_007177 CC(C)S(=O)(=O)c1c(C)c(C)n(Cc2ccc(F)c(Cl)c2)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G06 compound treatment 0.318 0.0104 0.84 0.324 0.011 1.0 1.3004 0.9963 2079294 Maybridge3_007178 Cc1c(C(=O)Oc2cccc(c2)C(F)(F)F)n(C)oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G07 compound treatment 0.323 0.0154 1.24 0.332 0.019 1.72 2.0985 0.9871 2079295 Maybridge3_007179 CCOC(=O)c1nc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)[nH]c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G08 compound treatment 0.331 0.0234 1.89 0.331 0.018 1.63 2.4899 0.9974 2079296 Maybridge3_007180 Cc1cc(NC(=O)c2ccc(cc2)C(F)(F)F)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G09 compound treatment 0.316 0.00844 0.68 0.326 0.013 1.18 1.3148 0.9656 1629065 Maybridge3_007181 CCCS(=O)(=O)c1c(C)c(C)n(Cc2cccc(Cl)c2)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G10 compound treatment 0.316 0.00844 0.68 0.33 0.017 1.54 1.5716 0.9321 1162435 Maybridge3_007182 O=C(Cn1c(=O)oc2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G11 compound treatment 0.318 0.0104 0.84 0.323 0.01 0.91 1.2362 0.9993 2079297 Maybridge3_007183 Cc1nc(cs1)c2nnc(SCc3ccc(Cl)cc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G12 compound treatment 0.328 0.0204 1.65 0.35 0.037 3.36 3.5386 0.9461 2079298 Maybridge3_007184 Oc1nnc(Sc2ccc(cn2)C(F)(F)F)n1C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G13 compound treatment 0.316 0.00844 0.68 0.332 0.019 1.72 1.7 0.9171 2079299 Maybridge3_007185 N/C(=N\O)/CSCc1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G14 compound treatment 0.316 0.00844 0.68 0.347 0.034 3.09 2.6627 0.8426 2079300 Maybridge3_007186 CSc1nn(CSc2nnc([nH]2)c3ccccc3F)c(=S)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G15 compound treatment 0.334 0.0264 2.13 0.342 0.029 2.63 3.3667 0.9945 2079301 Maybridge3_007187 CCn1nc(C)cc1C(=O)Oc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G16 compound treatment 0.334 0.0264 2.13 0.336 0.023 2.09 2.9816 1.0 2079302 Maybridge3_007188 Fc1ccccc1c2nnc(o2)c3ccc(OC(F)(F)F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G17 compound treatment 0.352 0.0444 3.58 0.36 0.047 4.27 5.547 0.9962 2079303 Maybridge3_007189 Cc1nc(sc1c2ccnn2C(=O)C3CC3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G18 compound treatment 0.325 0.0174 1.4 0.335 0.022 2.0 2.405 0.9851 2079304 Maybridge3_007190 COCc1cc(O)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G19 compound treatment 0.319 0.0114 0.92 0.32 0.007 0.64 1.1006 0.9836 1576217 Maybridge3_007191 NC(=O)c1csc(n1)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G20 compound treatment 0.327 0.0194 1.57 0.33 0.017 1.54 2.1979 1.0 2079305 Maybridge3_007192 Cc1cc(no1)c2onc(C)c2CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G21 compound treatment 0.35 0.0424 3.42 0.363 0.05 4.54 5.6257 0.9902 2079306 Maybridge3_007193 CCn1nc(C)cc1c2nnc(SCc3ccc(cc3)C(F)(F)F)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G22 compound treatment 0.318 0.0104 0.84 0.326 0.013 1.18 1.4287 0.9862 1440089 Maybridge3_007194 O=C(Nc1cccnc1)C2CCCS2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G23 mock treatment 0.304 -0.00356 -0.29 0.313 0.0 0.0 -0.2029 -0.7071 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 G24 positive control 0.096 -0.212 -17.04 0.094 -0.219 -19.88 -26.1031 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H01 compound treatment 0.324 0.0164 1.32 0.33 0.017 1.54 2.0271 0.9971 2079307 Maybridge3_007195 FC(F)(F)c1ccc(NC(=O)CSc2ncccc2C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H02 compound treatment 0.315 0.00744 0.6 0.335 0.022 2.0 1.8356 0.8804 2079308 Maybridge3_007196 O=C(c1ccccc1)n2nccc2c3cc(no3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H03 compound treatment 0.32 0.0124 1.0 0.323 0.01 0.91 1.3501 0.9988 2079309 Maybridge3_007197 Cc1ccc(cc1)c2n[nH]cc2Sc3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H04 compound treatment 0.323 0.0154 1.24 0.335 0.022 2.0 2.2911 0.974 2079310 Maybridge3_007198 COC(OC)c1c(cnn1c2ccc(F)cc2F)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H05 compound treatment 0.322 0.0144 1.16 0.329 0.016 1.45 1.849 0.9939 2079311 Maybridge3_007199 CCOC(=O)c1cc(on1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H06 compound treatment 0.35 0.0424 3.42 0.344 0.031 2.81 4.4062 0.9953 2079312 Maybridge3_007200 Cc1cc(no1)c2c(C(=O)N3CCCCC3)c(C)nn2c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H07 compound treatment 0.334 0.0264 2.13 0.334 0.021 1.91 2.8533 0.9985 2079313 Maybridge3_007201 CCOC(=O)c1sc2nc(C)c(cc2c1N)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H08 compound treatment 0.322 0.0144 1.16 0.325 0.012 1.09 1.5923 0.9995 2079314 Maybridge3_007202 COc1ccccc1c2nc(C)c3c(C)c(C#N)sc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H09 compound treatment 0.324 0.0164 1.32 0.333 0.02 1.82 2.2197 0.9879 1483111 Maybridge3_007203 O=C(N1CCCCC1)c2cc(on2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H10 compound treatment 0.32 0.0124 1.0 0.34 0.027 2.45 2.4412 0.9221 2079315 Maybridge3_007204 Cc1nnsc1c2c(C(=O)Oc3ccccc3)c(C)nn2c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H11 compound treatment 0.321 0.0134 1.08 0.315 0.002 0.18 0.8935 0.8144 2079316 Maybridge3_007205 CC(=O)n1nc(C)c(Sc2ccc(cn2)C(F)(F)F)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H12 compound treatment 0.318 0.0104 0.84 0.33 0.017 1.54 1.6855 0.9592 2079317 Maybridge3_007206 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)Oc3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H13 compound treatment 0.338 0.0304 2.45 0.345 0.032 2.9 3.7871 0.9964 2079318 Maybridge3_007207 Cc1nn(C(=O)c2ccc(C)cc2)c(C)c1Sc3nccn3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H14 compound treatment 0.334 0.0264 2.13 0.33 0.017 1.54 2.5965 0.9875 2079319 Maybridge3_007208 CC(C)(C)c1nc(no1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H15 compound treatment 0.321 0.0134 1.08 0.324 0.011 1.0 1.4712 0.9992 1557763 Maybridge3_007209 CC(=O)Nc1nc(C)c(Oc2ccc(Cl)cc2Cl)c(O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H16 compound treatment 0.325 0.0174 1.4 0.329 0.016 1.45 2.0199 0.9999 1518659 Maybridge3_007210 CN(C)Cc1coc2ccccc2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H17 compound treatment 0.328 0.0204 1.65 0.331 0.018 1.63 2.3191 1.0 2079320 Maybridge3_007211 CCOC(=O)c1csc(n1)c2cc(C)on2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H18 compound treatment 0.32 0.0124 1.0 0.334 0.021 1.91 2.0561 0.9549 1674091 Maybridge3_007212 NC(=O)c1ccc(Oc2ccc(Cl)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H19 compound treatment 0.326 0.0184 1.48 0.338 0.025 2.27 2.6545 0.9789 2079321 Maybridge3_007213 COc1ccc(cc1)c2csc(n2)c3cc(C)on3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H20 compound treatment 0.333 0.0254 2.05 0.332 0.019 1.72 2.6679 0.9963 2079322 Maybridge3_007214 COc1ccc(cc1)C2(O)NC(=NC(=C2C#N)SC)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H21 compound treatment 0.324 0.0164 1.32 0.332 0.019 1.72 2.1555 0.9915 2079323 Maybridge3_007215 C/C(=N\O)/c1cc(no1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H22 compound treatment 0.353 0.0454 3.66 0.364 0.051 4.63 5.8607 0.9932 1710904 Maybridge3_007216 CC(C)S(=O)(=O)c1cnc(COc2ccc(cc2)C(C)(C)C)nc1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H23 mock treatment 0.307 -5.63E-4 -0.05 0.317 0.004 0.36 0.2247 0.6141 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 H24 positive control 0.097 -0.211 -16.96 0.095 -0.218 -19.79 -25.982 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I01 compound treatment 0.311 0.00344 0.28 0.324 0.011 1.0 0.9018 0.8703 2079324 Maybridge3_007217 CCCS(=O)(=O)c1c(C)c(C)n(Cc2ccc(cc2)C(F)(F)F)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I02 compound treatment 0.318 0.0104 0.84 0.334 0.021 1.91 1.9422 0.9323 2079325 Maybridge3_007218 Cc1ccc(cc1)C(=O)CSc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I03 compound treatment 0.328 0.0204 1.65 0.338 0.025 2.27 2.7684 0.9876 2079326 Maybridge3_007219 Cc1cc(c2nc(no2)c3ccc(cc3)C(F)(F)F)n(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I04 compound treatment 0.321 0.0134 1.08 0.332 0.019 1.72 1.9847 0.9748 2079327 Maybridge3_007220 FC(F)(F)c1ccc(cc1)n2nnnc2c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I05 compound treatment 0.319 0.0114 0.92 0.337 0.024 2.18 2.1917 0.9266 1432024 Maybridge3_007221 CCOC(=O)c1csc(CS(=O)(=O)Cc2ccc(F)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I06 compound treatment 0.323 0.0154 1.24 0.338 0.025 2.27 2.4837 0.9599 2079328 Maybridge3_007222 Cc1nc(C)c(s1)c2nnc(o2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I07 compound treatment 0.311 0.00344 0.28 0.335 0.022 2.0 1.6078 0.7975 2079329 Maybridge3_007223 COC(=O)c1c(C)noc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I08 compound treatment 0.323 0.0154 1.24 0.345 0.032 2.9 2.9329 0.9283 2079330 Maybridge3_007224 COC(=O)c1ccc(cc1)c2nnco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I09 compound treatment 0.333 0.0254 2.05 0.333 0.02 1.82 2.7321 0.9982 1139760 Maybridge3_007225 CCOC(=O)c1sc(CS(=O)(=O)c2ccccn2)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I10 compound treatment 0.327 0.0194 1.57 0.337 0.024 2.18 2.6472 0.9868 2079331 Maybridge3_007226 FC(F)(F)c1cccnc1n2cncn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I11 compound treatment 0.316 0.00844 0.68 0.339 0.026 2.36 2.1493 0.8751 2079332 Maybridge3_007227 Cc1nc(cs1)c2nnc(SCc3ccc(cc3)C(F)(F)F)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I12 compound treatment 0.329 0.0214 1.73 0.328 0.015 1.36 2.1834 0.9931 2079333 Maybridge3_007228 Cc1cc(no1)c2onc(C)c2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I13 compound treatment 0.448 0.14 11.31 0.453 0.14 12.71 16.9825 0.9983 2079334 Maybridge3_007229 CCOC(=O)c1sc(nc1O)c2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I14 compound treatment 0.327 0.0194 1.57 0.331 0.018 1.63 2.2621 0.9998 2079335 Maybridge3_007230 COC(=O)c1c(C)nn(C)c1c2ccno2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I15 compound treatment 0.318 0.0104 0.84 0.336 0.023 2.09 2.0706 0.92 1275369 Maybridge3_007231 CC(C)n1c(SCC(=O)O)nc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I16 compound treatment 0.324 0.0164 1.32 0.343 0.03 2.72 2.8615 0.9451 2079336 Maybridge3_007232 Fc1ccccc1c2nnc(o2)c3ccccc3OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I17 compound treatment 0.373 0.0654 5.27 0.363 0.05 4.54 6.9353 0.9972 2079337 Maybridge3_007233 CC(C)NC(=O)n1nccc1c2sc(nc2C)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I18 compound treatment 0.329 0.0214 1.73 0.333 0.02 1.82 2.5044 0.9997 2079338 Maybridge3_007234 Cc1nc(cs1)c2nc(C)c(Cl)c(O)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I19 compound treatment 0.327 0.0194 1.57 0.335 0.022 2.0 2.5189 0.9927 2079339 Maybridge3_007235 CCOC(=O)Cc1csc(n1)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I20 compound treatment 0.333 0.0254 2.05 0.334 0.021 1.91 2.7963 0.9994 2079340 Maybridge3_007236 CSCc1c(C)noc1c2cc(C)on2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I21 compound treatment 0.364 0.0564 4.54 0.36 0.047 4.27 6.2303 0.9995 2079341 Maybridge3_007237 CCn1nc(C)cc1c2nnc(SCc3c(Cl)cccc3Cl)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I22 compound treatment 0.305 -0.00256 -0.21 0.313 0.0 0.0 -0.1459 -0.7071 2079342 Maybridge3_007238 C/C(=N\O)/c1csc(n1)c2snnc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I23 mock treatment 0.312 0.00444 0.36 0.317 0.004 0.36 0.5094 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 I24 positive control 0.098 -0.21 -16.88 0.095 -0.218 -19.79 -25.925 -0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J01 compound treatment 0.327 0.0194 1.57 0.331 0.018 1.63 2.2621 0.9998 2079343 Maybridge3_007239 FC(F)(F)c1cccnc1SCC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J02 compound treatment 0.324 0.0164 1.32 0.325 0.012 1.09 1.7062 0.9953 2079344 Maybridge3_007240 COC(=O)c1sccc1OCc2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J03 compound treatment 0.304 -0.00356 -0.29 0.321 0.008 0.73 0.3106 0.3978 2079345 Maybridge3_007241 Cn1c(SCc2ccccc2)nc3cc(cnc13)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J04 compound treatment 0.328 0.0204 1.65 0.346 0.033 3.0 3.2818 0.9602 2079346 Maybridge3_007242 COC(OC)c1nc(SCc2ccc(Cl)cc2)c(C#N)cc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J05 compound treatment 0.321 0.0134 1.08 0.325 0.012 1.09 1.5354 1.0 2079347 Maybridge3_007243 Cc1cc(no1)c2noc(n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J06 compound treatment 0.326 0.0184 1.48 0.341 0.028 2.54 2.847 0.9672 1680692 Maybridge3_007244 CNC(=O)c1c(C)nn(c1c2cc(C)on2)c3ccc(F)c(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J07 compound treatment 0.314 0.00644 0.52 0.329 0.016 1.45 1.3935 0.9037 2079348 Maybridge3_007245 CC(C)NC(=O)n1ncc(Sc2ccc(Cl)cc2)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J08 compound treatment 0.317 0.00944 0.76 0.327 0.014 1.27 1.436 0.9698 2079349 Maybridge3_007246 COc1ccc(OCc2ncc(cc2Cl)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J09 compound treatment 0.327 0.0194 1.57 0.331 0.018 1.63 2.2621 0.9998 1593404 Maybridge3_007247 CC(C)NC(=O)c1cc(on1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J10 compound treatment 0.324 0.0164 1.32 0.333 0.02 1.82 2.2197 0.9879 2079350 Maybridge3_007248 Cc1noc2ncnc(SCC(=O)Nc3ccccc3Cl)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J11 compound treatment 0.327 0.0194 1.57 0.334 0.021 1.91 2.4547 0.9952 2079351 Maybridge3_007249 COC(OC)c1ccc(C#N)c(SCC#N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J12 compound treatment 0.339 0.0314 2.53 0.349 0.036 3.27 4.1007 0.992 2079352 Maybridge3_007250 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)Nc3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J13 compound treatment 0.335 0.0274 2.21 0.348 0.035 3.18 3.8088 0.9842 1265777 Maybridge3_007251 Cc1nn(c(C)c1Sc2nccn2C)S(=O)(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J14 compound treatment 0.321 0.0134 1.08 0.333 0.02 1.82 2.0488 0.9694 2079353 Maybridge3_007252 Cc1c(sc2nc(nn12)C(F)(F)F)c3ccnc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J15 compound treatment 0.336 0.0284 2.29 0.347 0.034 3.09 3.8015 0.9892 2079354 Maybridge3_007253 Clc1ccc(cc1)c2csc(n2)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J16 compound treatment 0.328 0.0204 1.65 0.337 0.024 2.18 2.7042 0.9904 2079355 Maybridge3_007254 COC(OC)c1cc(O)nc(SC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J17 compound treatment 0.327 0.0194 1.57 0.328 0.015 1.36 2.0696 0.9976 2079356 Maybridge3_007255 Cc1cc(no1)c2nc(cs2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J18 compound treatment 0.372 0.0644 5.19 0.356 0.043 3.9 6.4291 0.9901 1193728 Maybridge3_007256 Cc1nc(C)c(Oc2ccc(Cl)cc2Cl)c(NCc3ccccc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J19 compound treatment 0.351 0.0434 3.5 0.347 0.034 3.09 4.6557 0.9981 1503780 Maybridge3_007257 CCOC(=O)c1c(C)noc1c2csc(Nc3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J20 compound treatment 0.33 0.0224 1.81 0.334 0.021 1.91 2.6255 0.9996 2079357 Maybridge3_007258 FC(F)(F)C1CCN(CC1)C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J21 compound treatment 0.327 0.0194 1.57 0.336 0.023 2.09 2.583 0.9899 1373051 Maybridge3_007259 Cc1nc2ccccn2c1c3ccnc(SCC(=O)Nc4ccccc4)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J22 compound treatment 0.318 0.0104 0.84 0.328 0.015 1.36 1.5571 0.9731 2079358 Maybridge3_007260 CC(C)S(=O)(=O)c1cnc(nc1N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J23 mock treatment 0.305 -0.00256 -0.21 0.31 -0.003 -0.27 -0.3385 -0.9906 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 J24 positive control 0.098 -0.21 -16.88 0.096 -0.217 -19.7 -25.8608 -0.997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K01 compound treatment 0.327 0.0194 1.57 0.329 0.016 1.45 2.1337 0.9993 2079359 Maybridge3_007261 CCn1nc(C)cc1/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K02 compound treatment 0.31 0.00244 0.2 0.322 0.009 0.82 0.7165 0.8527 2079360 Maybridge3_007262 FC(F)(F)c1ccc(SCC(=O)c2ccc(Cl)cc2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K03 compound treatment 0.322 0.0144 1.16 0.326 0.013 1.18 1.6565 1.0 2079361 Maybridge3_007263 Cc1cc(/C(=N\O)/N)n(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K04 compound treatment 0.32 0.0124 1.0 0.331 0.018 1.63 1.8635 0.9724 1239096 Maybridge3_007264 Clc1ccc(cc1)n2nnnc2c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K05 compound treatment 0.319 0.0114 0.92 0.333 0.02 1.82 1.935 0.9505 2079362 Maybridge3_007265 COC(=O)c1c(C)nn(C)c1c2snnc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K06 compound treatment 0.316 0.00844 0.68 0.336 0.023 2.09 1.9567 0.8912 2079363 Maybridge3_007266 Cc1nc(C)c(s1)c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K07 compound treatment 0.313 0.00544 0.44 0.331 0.018 1.63 1.4649 0.866 2079364 Maybridge3_007267 COC(=O)c1c(C)noc1c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K08 compound treatment 0.323 0.0154 1.24 0.329 0.016 1.45 1.906 0.997 2079365 Maybridge3_007268 Cc1cc(no1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K09 compound treatment 0.322 0.0144 1.16 0.328 0.015 1.36 1.7849 0.9969 1678374 Maybridge3_007269 NC(=O)Cc1cc(Br)sc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K10 compound treatment 0.54 0.232 18.72 0.552 0.239 21.69 28.5754 0.9973 2079366 Maybridge3_007270 O=C(Sc1ccccc1)c2ccno2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K11 compound treatment 0.35 0.0424 3.42 0.352 0.039 3.54 4.9196 0.9998 1659270 Maybridge3_007271 Clc1ccc(NC(=O)COc2ccc(cc2)C3SCCS3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K12 compound treatment 0.334 0.0264 2.13 0.354 0.041 3.72 4.137 0.9649 1495224 Maybridge3_007272 Cc1cc(no1)c2onc(C)c2C(=O)Nc3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K13 compound treatment 0.361 0.0534 4.3 0.354 0.041 3.72 5.6744 0.9974 2079367 Maybridge3_007273 CCn1nc(C)cc1c2nnc(SCC(=O)c3ccccc3)n2c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K14 compound treatment 0.323 0.0154 1.24 0.345 0.032 2.9 2.9329 0.9283 2079368 Maybridge3_007274 COC(=O)c1c(C)nn(c1c2cc(C)on2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K15 compound treatment 0.329 0.0214 1.73 0.336 0.023 2.09 2.6969 0.9955 2079369 Maybridge3_007275 Cc1nc(COc2cccc(Cl)c2)sc1c3ccn[nH]3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K16 compound treatment 0.331 0.0234 1.89 0.336 0.023 2.09 2.8108 0.9987 2079370 Maybridge3_007276 FC(F)(F)Oc1ccc(cc1)c2nnc(o2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K17 compound treatment 0.331 0.0234 1.89 0.326 0.013 1.18 2.169 0.9744 2079371 Maybridge3_007277 CCOC(=O)c1cc(CSc2nnc(SC)s2)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K18 compound treatment 0.329 0.0214 1.73 0.327 0.014 1.27 2.1193 0.9886 2079372 Maybridge3_007278 CSc1nc(N)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K19 compound treatment 0.323 0.0154 1.24 0.328 0.015 1.36 1.8418 0.999 2079373 Maybridge3_007279 Cc1nc(cs1)c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K20 compound treatment 0.32 0.0124 1.0 0.332 0.019 1.72 1.9277 0.9666 2079374 Maybridge3_007280 Cc1cc(OC(=O)c2ccno2)cc(C)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K21 compound treatment 0.326 0.0184 1.48 0.33 0.017 1.54 2.141 0.9998 2079375 Maybridge3_007281 Clc1ccc(cc1)c2nnc(CSc3nnc(SCC4CC4)s3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K22 compound treatment 0.332 0.0244 1.97 0.338 0.025 2.27 2.9961 0.9975 1381015 Maybridge3_007282 COC(=O)c1sccc1NC(=O)c2ccno2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K23 mock treatment 0.306 -0.00156 -0.13 0.313 0.0 0.0 -0.089 -0.7071 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 K24 positive control 0.1 -0.208 -16.71 0.097 -0.216 -19.61 -25.6828 -0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L01 compound treatment 0.252 -0.0556 -4.47 0.255 -0.058 -5.26 -6.8865 -0.9967 2079376 Maybridge3_007283 FC(F)(F)c1cccc(c1)C(=O)Sc2ncccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L02 compound treatment 0.319 0.0114 0.92 0.329 0.016 1.45 1.6782 0.9758 2079377 Maybridge3_007284 Cc1onc(c1c2ccn[nH]2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L03 compound treatment 0.318 0.0104 0.84 0.331 0.018 1.63 1.7497 0.9522 2079378 Maybridge3_007285 Cn1c(SCC(=O)O)nc2cc(cnc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L04 compound treatment 0.318 0.0104 0.84 0.321 0.008 0.73 1.1078 0.9973 2079379 Maybridge3_007286 COC(=O)c1cnn(c1/C=N/c2ccc(C)cc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L05 compound treatment 0.32 0.0124 1.0 0.321 0.008 0.73 1.2217 0.9875 2079380 Maybridge3_007287 CCOC(=O)c1cc(nn1C(=O)c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L06 compound treatment 0.312 0.00444 0.36 0.332 0.019 1.72 1.4722 0.8359 2079381 Maybridge3_007288 Cc1nccc(n1)c2cc(no2)c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L07 compound treatment 0.33 0.0224 1.81 0.339 0.026 2.36 2.9464 0.9913 2079382 Maybridge3_007289 COC(OC)c1ccnc(SCC(=O)Nc2ccc(cc2)C(C)C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L08 compound treatment 0.328 0.0204 1.65 0.336 0.023 2.09 2.64 0.9931 2079383 Maybridge3_007290 CC(=O)Nc1ccc(OCc2ncc(cc2Cl)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L09 compound treatment 0.327 0.0194 1.57 0.334 0.021 1.91 2.4547 0.9952 2079384 Maybridge3_007291 Cc1n[nH]c(C)c1Sc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L10 compound treatment 0.33 0.0224 1.81 0.333 0.02 1.82 2.5613 1.0 2079385 Maybridge3_007292 CC1=C(Oc2ccc(Cl)cc2)C(C)(O)N=C(N1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L11 compound treatment 0.33 0.0224 1.81 0.337 0.024 2.18 2.8181 0.9957 2079386 Maybridge3_007293 COC(OC)c1ccc(C#N)c(SCC(=O)Nc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L12 compound treatment 0.322 0.0144 1.16 0.336 0.023 2.09 2.2983 0.9618 2079387 Maybridge3_007294 CC(=O)Nc1cc(O)nc(n1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L13 compound treatment 0.32 0.0124 1.0 0.331 0.018 1.63 1.8635 0.9724 2079388 Maybridge3_007295 CSc1nc(/C=N/c2ccc(Cl)cc2Cl)ccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L14 compound treatment 0.32 0.0124 1.0 0.327 0.014 1.27 1.6068 0.9931 2079389 Maybridge3_007296 CSc1nc(N)nc(COc2ccccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L15 compound treatment 0.325 0.0174 1.4 0.334 0.021 1.91 2.3408 0.9887 1485989 Maybridge3_007297 CCOC(=O)c1cc(on1)c2csc(Nc3ccccc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L16 compound treatment 0.328 0.0204 1.65 0.334 0.021 1.91 2.5116 0.9973 2079390 Maybridge3_007298 COC(OC)c1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L17 compound treatment 0.338 0.0304 2.45 0.349 0.036 3.27 4.0438 0.99 2079391 Maybridge3_007299 Cc1ccccc1CSc2cnc(C)nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L18 compound treatment 0.334 0.0264 2.13 0.343 0.03 2.72 3.4309 0.9926 2079392 Maybridge3_007300 FC(F)(F)c1ccc(nc1)c2nc(cs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L19 compound treatment 0.325 0.0174 1.4 0.329 0.016 1.45 2.0199 0.9999 2079393 Maybridge3_007301 Cc1nc(cs1)c2cc(no2)c3nc(no3)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L20 compound treatment 0.33 0.0224 1.81 0.332 0.019 1.72 2.4971 0.9997 2079394 Maybridge3_007302 FC(F)(F)c1cnc(NN2C3CSC2CS3)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L21 compound treatment 0.33 0.0224 1.81 0.341 0.028 2.54 3.0748 0.986 1456968 Maybridge3_007303 COC(Cn1c(SCc2ccccc2)nnc1c3ccccc3)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L22 compound treatment 0.326 0.0184 1.48 0.328 0.015 1.36 2.0126 0.9991 2079395 Maybridge3_007304 CSc1nc(nc(N)c1C#N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L23 mock treatment 0.311 0.00344 0.28 0.313 0.0 0.0 0.1957 0.7071 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 L24 positive control 0.098 -0.21 -16.88 0.099 -0.214 -19.43 -25.6683 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M01 compound treatment 0.314 0.00644 0.52 0.319 0.006 0.54 0.7517 0.9997 1542413 Maybridge3_007305 Cc1c(C)n(CC2CC2)c(c1C#N)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M02 compound treatment 0.315 0.00744 0.6 0.322 0.009 0.82 1.0012 0.9884 2079396 Maybridge3_007306 O/N=C/c1nn(cc1Br)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M03 compound treatment 0.312 0.00444 0.36 0.322 0.009 0.82 0.8303 0.9312 2079397 Maybridge3_007307 CCOC(=O)c1csc(Cc2c(Cl)cccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M04 compound treatment 0.317 0.00944 0.76 0.329 0.016 1.45 1.5643 0.9544 2079398 Maybridge3_007308 Clc1ccc(cc1)c2nnc(Cc3csc(n3)c4cccs4)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M05 compound treatment 0.321 0.0134 1.08 0.321 0.008 0.73 1.2786 0.9812 2079399 Maybridge3_007309 Cn1c(SCC(=O)Nc2cccc(Cl)c2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M06 compound treatment 0.326 0.0184 1.48 0.327 0.014 1.27 1.9484 0.997 2079400 Maybridge3_007310 Cc1c(c2nc(no2)c3ccc(cc3)C(C)(C)C)n(C)oc1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M07 compound treatment 0.319 0.0114 0.92 0.333 0.02 1.82 1.935 0.9505 2079401 Maybridge3_007311 CSc1nnc(SCC#N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M08 compound treatment 0.328 0.0204 1.65 0.338 0.025 2.27 2.7684 0.9876 2079402 Maybridge3_007312 Cc1cc(no1)c2nc(no2)c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M09 compound treatment 0.32 0.0124 1.0 0.335 0.022 2.0 2.1203 0.9491 2079403 Maybridge3_007313 CCOC(=O)Cn1nnc(n1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M10 compound treatment 0.448 0.14 11.31 0.467 0.154 13.98 17.8811 0.9945 2079404 Maybridge3_007314 Cc1ccc(SC(=O)c2ccno2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M11 compound treatment 0.315 0.00744 0.6 0.328 0.015 1.36 1.3863 0.932 1129579 Maybridge3_007315 Cc1nc(cs1)c2nnc(SCC(=O)c3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M12 compound treatment 0.327 0.0194 1.57 0.332 0.019 1.72 2.3263 0.9988 2079405 Maybridge3_007316 CC(C)(C)c1nn(Cc2ccccc2)c(C(=O)O)c1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M13 compound treatment 0.322 0.0144 1.16 0.327 0.014 1.27 1.7207 0.999 1238054 Maybridge3_007317 CCOC(=O)c1sc(nc1CSc2nnc(SC)s2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M14 compound treatment 0.322 0.0144 1.16 0.331 0.018 1.63 1.9774 0.9861 2079406 Maybridge3_007318 Cc1cc(O)nc(n1)c2ccccc2OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M15 compound treatment 0.355 0.0474 3.82 0.365 0.052 4.72 6.0388 0.9945 2079407 Maybridge3_007319 CC(=O)n1nccc1c2sc(COc3cccc(Cl)c3)nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M16 compound treatment 0.315 0.00744 0.6 0.325 0.012 1.09 1.1937 0.9603 2079408 Maybridge3_007320 FC(F)(F)Oc1ccccc1c2nnc(o2)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M17 compound treatment 0.322 0.0144 1.16 0.329 0.016 1.45 1.849 0.9939 2079409 Maybridge3_007321 Cc1nc(cs1)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M18 compound treatment 0.327 0.0194 1.57 0.337 0.024 2.18 2.6472 0.9868 2079410 Maybridge3_007322 Cc1nc(cs1)c2ccnc(n2)c3cc(Cl)cc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M19 compound treatment 0.325 0.0174 1.4 0.327 0.014 1.27 1.8915 0.9988 1532224 Maybridge3_007323 Cc1nc(cs1)c2nnc(o2)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M20 compound treatment 0.258 -0.0496 -3.99 0.262 -0.051 -4.63 -6.0956 -0.9973 2079411 Maybridge3_007324 FC(F)(F)c1cccnc1SC(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M21 compound treatment 0.321 0.0134 1.08 0.329 0.016 1.45 1.7921 0.9895 2079412 Maybridge3_007325 Cc1cc(no1)c2nnc(o2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M22 compound treatment 0.323 0.0154 1.24 0.326 0.013 1.18 1.7134 0.9997 1420687 Maybridge3_007326 Nc1nccc(n1)c2csc(COc3ccc(Cl)cc3)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M23 mock treatment 0.313 0.00544 0.44 0.31 -0.003 -0.27 0.1171 0.227 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 M24 positive control 0.1 -0.208 -16.71 0.099 -0.214 -19.43 -25.5544 -0.9972 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N01 compound treatment 0.328 0.0204 1.65 0.334 0.021 1.91 2.5116 0.9973 2079413 Maybridge3_007327 COC(=O)c1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N02 compound treatment 0.32 0.0124 1.0 0.328 0.015 1.36 1.671 0.9886 1221274 Maybridge3_007328 CC(C)NC(=O)n1nccc1c2c(C)onc2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N03 compound treatment 0.332 0.0244 1.97 0.33 0.017 1.54 2.4826 0.9928 2079414 Maybridge3_007329 COc1nc(C)nc(C)c1Oc2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N04 compound treatment 0.316 0.00844 0.68 0.33 0.017 1.54 1.5716 0.9321 2079415 Maybridge3_007330 CC(=O)Nc1nccc(n1)c2cc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N05 compound treatment 0.323 0.0154 1.24 0.331 0.018 1.63 2.0344 0.9909 2079416 Maybridge3_007331 COC(OC)c1ccnc(SCc2ccccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N06 compound treatment 0.334 0.0264 2.13 0.347 0.034 3.09 3.6877 0.9836 2079417 Maybridge3_007332 COC(=O)c1cnn(c1/C=N/O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N07 compound treatment 0.315 0.00744 0.6 0.329 0.016 1.45 1.4505 0.9233 2079418 Maybridge3_007333 Cc1cc(no1)c2noc(n2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N08 compound treatment 0.323 0.0154 1.24 0.334 0.021 1.91 2.2269 0.9785 2079419 Maybridge3_007334 CCOC(=O)c1sc2nc(nn2c1C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N09 compound treatment 0.322 0.0144 1.16 0.336 0.023 2.09 2.2983 0.9618 2079420 Maybridge3_007335 COC(OC)c1ccc(C#N)c(SC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N10 compound treatment 0.338 0.0304 2.45 0.347 0.034 3.09 3.9154 0.9935 1537540 Maybridge3_007336 COc1ccc(cc1)c2csc(n2)c3c(C)noc3N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N11 compound treatment 0.336 0.0284 2.29 0.347 0.034 3.09 3.8015 0.9892 2079421 Maybridge3_007337 COC(OC)c1ccc2c(N)c(C#N)sc2n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N12 compound treatment 0.332 0.0244 1.97 0.337 0.024 2.18 2.9319 0.9987 1600614 Maybridge3_007338 CC(=O)Nc1onc(C)c1c2nc(cs2)c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N13 compound treatment 0.332 0.0244 1.97 0.342 0.029 2.63 3.2529 0.9897 2079422 Maybridge3_007339 CSc1nc(/C=N/c2ccc(C)cc2)ccc1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N14 compound treatment 0.326 0.0184 1.48 0.341 0.028 2.54 2.847 0.9672 1678205 Maybridge3_007340 COc1ccc(OCc2nc(N)nc(SC)n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N15 compound treatment 0.329 0.0214 1.73 0.339 0.026 2.36 2.8895 0.9882 2079423 Maybridge3_007341 Cc1cc(no1)c2nc(cs2)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N16 compound treatment 0.332 0.0244 1.97 0.331 0.018 1.63 2.5468 0.9957 2079424 Maybridge3_007342 COC(OC)c1cc(O)nc(SCc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N17 compound treatment 0.34 0.0324 2.61 0.336 0.023 2.09 3.3233 0.9938 1403096 Maybridge3_007343 COCc1cc(nc(n1)c2csc(C)n2)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N18 compound treatment 0.324 0.0164 1.32 0.33 0.017 1.54 2.0271 0.9971 2079425 Maybridge3_007344 CCOC(=O)c1cc2nc3sccn3c2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N19 compound treatment 0.325 0.0174 1.4 0.33 0.017 1.54 2.0841 0.9989 1402976 Maybridge3_007345 Cc1nc(cs1)c2cc(no2)c3nc(no3)c4ccc(cc4)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N20 compound treatment 0.336 0.0284 2.29 0.341 0.028 2.54 3.4164 0.9986 2079426 Maybridge3_007346 Cc1nc(no1)c2ccc(cc2)c3csc(n3)c4cnccc4C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N21 compound treatment 0.333 0.0254 2.05 0.333 0.02 1.82 2.7321 0.9982 2079427 Maybridge3_007347 COC(Cn1c(SC)nnc1c2ccc(Cl)cc2)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N22 compound treatment 0.32 0.0124 1.0 0.326 0.013 1.18 1.5426 0.9967 2079428 Maybridge3_007348 CSc1nnc(c2ccccc2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N23 mock treatment 0.312 0.00444 0.36 0.317 0.004 0.36 0.5094 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 N24 positive control 0.098 -0.21 -16.88 0.099 -0.214 -19.43 -25.6683 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O01 compound treatment 0.334 0.0264 2.13 0.339 0.026 2.36 3.1742 0.9987 1396462 Maybridge3_007349 Cc1c(C)n(CC2CC2)c(NC(=O)c3cccs3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O02 compound treatment 0.323 0.0154 1.24 0.335 0.022 2.0 2.2911 0.974 1488551 Maybridge3_007350 Clc1cccc(c1)c2nnc(CCn3c(=O)oc4ccccc34)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O03 compound treatment 0.324 0.0164 1.32 0.325 0.012 1.09 1.7062 0.9953 2079429 Maybridge3_007351 CCOC(=O)c1csc(CS(=O)(=O)c2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O04 compound treatment 0.319 0.0114 0.92 0.326 0.013 1.18 1.4857 0.9925 1723271 Maybridge3_007352 Clc1cccc(OC(=O)CCn2c(=O)oc3ccccc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O05 compound treatment 0.311 0.00344 0.28 0.323 0.01 0.91 0.8376 0.8826 2079430 Maybridge3_007353 Oc1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)n1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O06 compound treatment 0.341 0.0334 2.69 0.35 0.037 3.36 4.2788 0.994 2079431 Maybridge3_007354 Cc1nc(no1)c2ccc(Oc3ncc(cc3Cl)C(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O07 compound treatment 0.323 0.0154 1.24 0.335 0.022 2.0 2.2911 0.974 2079432 Maybridge3_007355 CCOC(=O)c1csc(CS(=O)(=O)Cc2cccc(c2)C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O08 compound treatment 0.35 0.0424 3.42 0.36 0.047 4.27 5.4331 0.994 2079433 Maybridge3_007356 Cc1cc(no1)C(=O)Sc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O09 compound treatment 0.331 0.0234 1.89 0.336 0.023 2.09 2.8108 0.9987 2079434 Maybridge3_007357 Cc1nc(cs1)c2nnc(SCc3ccc(C)cc3)n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O10 compound treatment 0.323 0.0154 1.24 0.327 0.014 1.27 1.7776 0.9999 2079435 Maybridge3_007358 FC(F)(F)c1nnc(Sc2ccc(cn2)C(F)(F)F)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O11 compound treatment 0.348 0.0404 3.26 0.354 0.041 3.72 4.9341 0.9978 2079436 Maybridge3_007359 CC(C)c1ccc(NC(=O)CSc2nc3nc(C)cc(C)n3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O12 compound treatment 0.33 0.0224 1.81 0.336 0.023 2.09 2.7539 0.9974 2079437 Maybridge3_007360 Cc1nnc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O13 compound treatment 0.317 0.00944 0.76 0.328 0.015 1.36 1.5002 0.9621 2079438 Maybridge3_007361 O=C(CSc1nnc(Cc2ccsc2)o1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O14 compound treatment 0.336 0.0284 2.29 0.348 0.035 3.18 3.8657 0.9871 2079439 Maybridge3_007362 CSc1nn(CSc2c(Cl)cccc2Cl)c(=S)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O15 compound treatment 0.334 0.0264 2.13 0.332 0.019 1.72 2.7249 0.9945 2079440 Maybridge3_007363 CCOC(=O)CSc1nc2cc(Cl)ccc2n1C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O16 compound treatment 0.332 0.0244 1.97 0.336 0.023 2.09 2.8677 0.9996 1125675 Maybridge3_007364 O=C(C1CC1)n2nccc2c3csc(n3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O17 compound treatment 0.349 0.0414 3.34 0.371 0.058 5.26 6.0822 0.9758 2079441 Maybridge3_007365 Cc1nc(sc1c2ccnc(C)n2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O18 compound treatment 0.33 0.0224 1.81 0.329 0.016 1.45 2.3046 0.9941 1320064 Maybridge3_007366 COc1nc(N)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O19 compound treatment 0.333 0.0254 2.05 0.344 0.031 2.81 3.4382 0.9878 1173791 Maybridge3_007367 CCOC(=O)c1sc(nc1CSc2nccn2C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O20 compound treatment 0.331 0.0234 1.89 0.329 0.016 1.45 2.3615 0.9916 2079442 Maybridge3_007368 Cc1ccc(OC(=O)c2ccno2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O21 compound treatment 0.332 0.0244 1.97 0.334 0.021 1.91 2.7394 0.9999 2079443 Maybridge3_007369 Cc1cc(no1)c2nnc(o2)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O22 compound treatment 0.329 0.0214 1.73 0.332 0.019 1.72 2.4402 1.0 2079444 Maybridge3_007370 FC(F)(F)c1ccc(nc1)S(=O)Cc2c(Cl)cccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O23 mock treatment 0.318 0.0104 0.84 0.319 0.006 0.54 0.9794 0.9779 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 O24 positive control 0.099 -0.209 -16.79 0.099 -0.214 -19.43 -25.6113 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P01 compound treatment 0.351 0.0434 3.5 0.36 0.047 4.27 5.4901 0.9951 2079445 Maybridge3_007371 Fc1ccc(SC(=O)Cn2nnc(n2)c3ccc(cc3)C(F)(F)F)c(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P02 compound treatment 0.34 0.0324 2.61 0.352 0.039 3.54 4.3502 0.9888 2079446 Maybridge3_007372 Clc1ccc(NC(=O)CSc2nccc(n2)c3cc(no3)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P03 compound treatment 0.342 0.0344 2.77 0.355 0.042 3.81 4.6567 0.9878 1184483 Maybridge3_007373 CN(C)C(=O)Oc1nc(nc(C)c1Oc2ccc(C)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P04 compound treatment 0.32 0.0124 1.0 0.331 0.018 1.63 1.8635 0.9724 2079447 Maybridge3_007374 Cc1onc(c1c2ccnc(C)n2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P05 compound treatment 0.327 0.0194 1.57 0.326 0.013 1.18 1.9412 0.9903 2079448 Maybridge3_007375 CCOC(=O)c1cc(C#N)c(SC)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P06 compound treatment 0.32 0.0124 1.0 0.325 0.012 1.09 1.4784 0.9991 1625291 Maybridge3_007376 Cc1nn(C(=O)C2CC2)c(C)c1Oc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P07 compound treatment 0.317 0.00944 0.76 0.332 0.019 1.72 1.7569 0.9322 2079449 Maybridge3_007377 COc1ccc(OC/C(=N/O)/N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P08 compound treatment 0.324 0.0164 1.32 0.331 0.018 1.63 2.0913 0.9945 2079450 Maybridge3_007378 Cc1c(sc2nc(nn12)c3ccc(Cl)cc3)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P09 compound treatment 0.323 0.0154 1.24 0.329 0.016 1.45 1.906 0.997 2079451 Maybridge3_007379 COC(OC)c1ccc(C#N)c(SCc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P10 compound treatment 0.336 0.0284 2.29 0.338 0.025 2.27 3.2239 1.0 1253523 Maybridge3_007380 Cc1noc(N)c1c2nc(cs2)c3ccc(Cl)cc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P11 compound treatment 0.343 0.0354 2.85 0.338 0.025 2.27 3.6225 0.9936 2079452 Maybridge3_007381 Cc1nn(C(=O)c2ccc(C)cc2)c(C)c1Sc3ncccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P12 compound treatment 0.321 0.0134 1.08 0.326 0.013 1.18 1.5995 0.9991 2079453 Maybridge3_007382 N/C(=N\O)/c1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P13 compound treatment 0.267 -0.0406 -3.27 0.257 -0.056 -5.08 -5.904 -0.9771 2079454 Maybridge3_007383 Cc1noc(C)c1C(=O)Sc2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P14 compound treatment 0.33 0.0224 1.81 0.331 0.018 1.63 2.4329 0.9987 2079455 Maybridge3_007384 COC(OC)c1nc(SCc2ccc(Cl)cc2)ncc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P15 compound treatment 0.324 0.0164 1.32 0.334 0.021 1.91 2.2839 0.9841 2079456 Maybridge3_007385 COc1cc(C)nc(n1)c2csc(C)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P16 compound treatment 0.329 0.0214 1.73 0.332 0.019 1.72 2.4402 1.0 2079457 Maybridge3_007386 COC(OC)c1cc(O)nc(SCC(=O)c2ccc(C)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P17 compound treatment 0.328 0.0204 1.65 0.332 0.019 1.72 2.3832 0.9997 2079458 Maybridge3_007387 CCOC(=O)c1nc(C)sc1c2cc[nH]n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P18 compound treatment 0.32 0.0124 1.0 0.329 0.016 1.45 1.7352 0.9835 2079459 Maybridge3_007388 CCOC(=O)c1cnc(nc1O)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P19 compound treatment 0.319 0.0114 0.92 0.326 0.013 1.18 1.4857 0.9925 2079460 Maybridge3_007389 Cc1cc(n[nH]1)C(F)(F)Sc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P20 compound treatment 0.326 0.0184 1.48 0.33 0.017 1.54 2.141 0.9998 2079461 Maybridge3_007390 CCC(=O)Nc1ccc(OCc2ncc(cc2Cl)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P21 compound treatment 0.33 0.0224 1.81 0.337 0.024 2.18 2.8181 0.9957 2079462 Maybridge3_007391 COC(Cn1c(SCC=C)nnc1c2ccc(Cl)cc2)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P22 compound treatment 0.348 0.0404 3.26 0.348 0.035 3.18 4.549 0.9999 2079463 Maybridge3_007392 Cc1c(Sc2ccc(Cl)cc2)cnn1CCC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P23 mock treatment 0.315 0.00744 0.6 0.317 0.004 0.36 0.6802 0.9712 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1451 P24 positive control 0.102 -0.206 -16.55 0.102 -0.211 -19.15 -25.248 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A01 compound treatment 0.304 -0.0179 -1.44 0.303 -0.0158 -1.43 -2.0309 -1.0 2079464 Maybridge3_007393 Cc1ccc(SCC(=N)N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A02 compound treatment 0.3 -0.0219 -1.76 0.305 -0.0138 -1.25 -2.1303 -0.9858 2079465 Maybridge3_007394 FC(F)(F)COc1ccc(cn1)C(=O)NC(=N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A03 compound treatment 0.299 -0.0229 -1.84 0.315 -0.00377 -0.34 -1.5454 -0.8242 1583520 Maybridge3_007395 CN(CCO)c1ccc(C#N)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A04 compound treatment 0.301 -0.0209 -1.68 0.304 -0.0148 -1.34 -2.1376 -0.9936 1492778 Maybridge3_007396 Clc1cccc(Cl)c1SC(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A05 compound treatment 0.299 -0.0229 -1.84 0.302 -0.0168 -1.52 -2.3798 -0.9955 2079466 Maybridge3_007397 COC(=O)c1c(C)nn(C(=O)C)c1COc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A06 compound treatment 0.303 -0.0189 -1.52 0.304 -0.0148 -1.34 -2.0237 -0.998 2079467 Maybridge3_007398 Oc1nnc(SCC(=O)N2CCC(CC2)C(F)(F)F)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A07 compound treatment 0.307 -0.0149 -1.2 0.313 -0.00577 -0.52 -1.2182 -0.9309 2079468 Maybridge3_007399 CCOC(=O)c1cc(C)nc(Sc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A08 compound treatment 0.31 -0.0119 -0.96 0.314 -0.00477 -0.43 -0.9832 -0.9355 1610414 Maybridge3_007400 CC(C)(C)c1ccc(NC(=O)CSc2nnc(s2)c3cnccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A09 compound treatment 0.303 -0.0189 -1.52 0.3 -0.0188 -1.7 -2.2804 -0.9984 2079469 Maybridge3_007401 COC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)c3ccccc3)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A10 compound treatment 0.376 0.0541 4.36 0.375 0.0562 5.1 6.6901 0.9969 2079470 Maybridge3_007402 Cn1c(SCc2cc(=O)oc3cc(O)ccc23)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A11 compound treatment 0.302 -0.0199 -1.6 0.306 -0.0128 -1.16 -1.9522 -0.9874 2079471 Maybridge3_007403 CC(=O)Nc1ccc(OC(=O)c2cccc(n2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A12 compound treatment 0.306 -0.0159 -1.28 0.308 -0.0108 -0.98 -1.5961 -0.9911 2079472 Maybridge3_007404 N/C(=N\O)/Cc1ccc(Oc2c(Cl)cncc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A13 compound treatment 0.305 -0.0169 -1.36 0.304 -0.0148 -1.34 -1.9098 -1.0 2079473 Maybridge3_007405 FC(F)(F)c1ccc(nc1)C(=N)NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A14 compound treatment 0.324 0.0021 0.17 0.32 0.00123 0.11 0.199 0.9798 2079474 Maybridge3_007406 Cn1nc(cc1C(=O)Sc2ccccc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A15 compound treatment 0.292 -0.0299 -2.41 0.295 -0.0238 -2.16 -3.2277 -0.9985 2079475 Maybridge3_007407 Clc1cc(Cl)cc(c1)C(=N)NC(=O)CCn2c(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A16 compound treatment 0.303 -0.0189 -1.52 0.303 -0.0158 -1.43 -2.0879 -0.9995 2079476 Maybridge3_007408 CC1=N/C(=C\c2ccc3ccccc3c2)/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A17 compound treatment 0.305 -0.0169 -1.36 0.301 -0.0178 -1.61 -2.1023 -0.9964 1640008 Maybridge3_007409 CS(=O)(=O)N1CCN(CC1)c2c(Cl)cncc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A18 compound treatment 0.304 -0.0179 -1.44 0.3 -0.0188 -1.7 -2.2235 -0.9965 2079477 Maybridge3_007410 CC(=O)N/C(=C\c1ccc(NC(=O)C)cc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A19 compound treatment 0.304 -0.0179 -1.44 0.301 -0.0178 -1.61 -2.1593 -0.9984 2079478 Maybridge3_007411 Cc1ccc(CSc2nnc(s2)c3ccc(cn3)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A20 compound treatment 0.306 -0.0159 -1.28 0.307 -0.0118 -1.07 -1.6603 -0.9959 2079479 Maybridge3_007412 COc1cc(/C=C(\NC(=O)C)/C(=O)O)ccc1OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A21 compound treatment 0.343 0.0211 1.7 0.335 0.0162 1.47 2.2437 0.9975 2079480 Maybridge3_007413 CSC1=NNC(S1)c2nn(C)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A22 compound treatment 0.303 -0.0189 -1.52 0.303 -0.0158 -1.43 -2.0879 -0.9995 2079481 Maybridge3_007414 COc1ccc(CC(NC(=O)C)C(=O)O)c(Cl)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A23 mock treatment 0.294 -0.0279 -2.25 0.291 -0.0278 -2.52 -3.3705 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 A24 positive control 0.086 -0.236 -19.0 0.084 -0.235 -21.31 -28.5006 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B01 compound treatment 0.321 -8.96E-4 -0.07 0.32 0.00123 0.11 0.0282 0.2118 2079482 Maybridge3_007415 CC(C)(C)c1ccc(cc1)c2nnc(SCC(=O)c3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B02 mock treatment 0.326 0.0041 0.33 0.324 0.00523 0.48 0.5697 0.9843 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B03 compound treatment 0.333 0.0111 0.89 0.337 0.0182 1.66 1.8027 0.9582 1168360 Maybridge3_007416 Fc1ccc(C(=O)N2CCN(CC2)c3nc(ns3)c4cccs4)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B04 mock treatment 0.322 1.04E-4 0.01 0.322 0.00323 0.29 0.2135 0.727 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B05 compound treatment 0.321 -8.96E-4 -0.07 0.322 0.00323 0.29 0.1566 0.518 1296150 Maybridge3_007417 COc1ccc(NC(=O)c2cccs2)cn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B06 mock treatment 0.314 -0.0079 -0.64 0.322 0.00323 0.29 -0.242 -0.3456 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B07 compound treatment 0.313 -0.0089 -0.72 0.319 2.34E-4 0.02 -0.4915 -0.6858 1299827 Maybridge3_007418 CN1CCN(CC1)c2ccc(NC(=O)c3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B08 mock treatment 0.318 -0.0039 -0.31 0.322 0.00323 0.29 -0.0142 -0.0331 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B09 compound treatment 0.346 0.0241 1.94 0.327 0.00823 0.75 1.901 0.914 1308684 Maybridge3_007419 CC(=O)Nc1cccc(c1)C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B10 mock treatment 0.319 -0.0029 -0.23 0.319 2.34E-4 0.02 -0.1498 -0.64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B11 compound treatment 0.316 -0.0059 -0.47 0.314 -0.00477 -0.43 -0.6416 -0.9989 2079483 Maybridge3_007420 CNc1nc2cccnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B12 mock treatment 0.316 -0.0059 -0.47 0.316 -0.00277 -0.25 -0.5132 -0.9556 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B13 compound treatment 0.32 -0.0019 -0.15 0.315 -0.00377 -0.34 -0.3496 -0.934 2079484 Maybridge3_007421 CC(C)(C)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B14 mock treatment 0.319 -0.0029 -0.23 0.319 2.34E-4 0.02 -0.1498 -0.64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B15 compound treatment 0.317 -0.0049 -0.39 0.315 -0.00377 -0.34 -0.5205 -0.9975 2079485 Maybridge3_007422 CC(=O)Nc1ccc(Br)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B16 mock treatment 0.32 -0.0019 -0.15 0.317 -0.00177 -0.16 -0.2213 -0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B17 compound treatment 0.323 0.0011 0.09 0.318 -7.66E-4 -0.07 0.0137 0.1217 2079486 Maybridge3_007423 CCOc1ccc(cc1)C(=O)/C=C/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B18 mock treatment 0.322 1.04E-4 0.01 0.318 -7.66E-4 -0.07 -0.0432 -0.6171 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B19 mock treatment 0.322 1.04E-4 0.01 0.315 -0.00377 -0.34 -0.2358 -0.6895 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B20 mock treatment 0.32 -0.0019 -0.15 0.315 -0.00377 -0.34 -0.3496 -0.934 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B21 mock treatment 0.315 -0.0069 -0.56 0.315 -0.00377 -0.34 -0.6344 -0.9728 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B22 mock treatment 0.316 -0.0059 -0.47 0.312 -0.00677 -0.61 -0.77 -0.9919 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B23 mock treatment 0.305 -0.0169 -1.36 0.301 -0.0178 -1.61 -2.1023 -0.9964 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 B24 positive control 0.087 -0.235 -18.92 0.087 -0.232 -21.04 -28.2511 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C01 compound treatment 0.318 -0.0039 -0.31 0.312 -0.00677 -0.61 -0.6561 -0.9514 2079487 Maybridge3_007424 CSc1nc(N)nc(CSc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C02 compound treatment 0.334 0.0121 0.97 0.337 0.0182 1.66 1.8596 0.9681 1485294 Maybridge3_007425 CSc1nc2CCCCc2c(c3cccs3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C03 compound treatment 0.309 -0.0129 -1.04 0.311 -0.00777 -0.7 -1.2327 -0.9822 2079488 Maybridge3_007426 Oc1nnc(SCc2ncc(cc2Cl)C(F)(F)F)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C04 compound treatment 0.345 0.0231 1.86 0.349 0.0302 2.74 3.2562 0.9821 2079489 Maybridge3_007427 CCOC(=O)c1nc(C)nc(Sc2ccccc2)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C05 compound treatment 0.318 -0.0039 -0.31 0.321 0.00223 0.2 -0.0784 -0.2099 2079490 Maybridge3_007428 Nc1c(cnn1c2ncc(cc2Cl)C(F)(F)F)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C06 compound treatment 0.328 0.0061 0.49 0.321 0.00223 0.2 0.491 0.9233 2079491 Maybridge3_007429 c1ncn(n1)c2ccc(cn2)c3nc(cs3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C07 compound treatment 0.316 -0.0059 -0.47 0.31 -0.00877 -0.8 -0.8983 -0.9695 2079492 Maybridge3_007430 CSc1nnc(c2cc(C)on2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C08 compound treatment 0.319 -0.0029 -0.23 0.322 0.00323 0.29 0.0427 0.1139 1018221 Maybridge3_007431 CCOC(=O)c1cnc(O)cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C09 compound treatment 0.324 0.0021 0.17 0.315 -0.00377 -0.34 -0.1219 -0.3195 1205106 Maybridge3_007432 CCOC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)c3ccccc3)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C10 compound treatment 0.326 0.0041 0.33 0.329 0.0102 0.93 0.8906 0.9032 1020096 Maybridge3_007433 OC(=O)c1cnc(O)cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C11 compound treatment 0.32 -0.0019 -0.15 0.306 -0.0128 -1.16 -0.9273 -0.7934 2079493 Maybridge3_007434 Cc1nc(nc(Sc2nnc([nH]2)c3ccccc3)c1C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C12 compound treatment 0.334 0.0121 0.97 0.34 0.0212 1.93 2.0522 0.9501 1312476 Maybridge3_007435 Clc1ccc2nc(sc2c1)N3CCN(CC#N)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C13 compound treatment 0.329 0.0071 0.57 0.31 -0.00877 -0.8 -0.1581 -0.1613 2079494 Maybridge3_007436 Cn1nc(cc1C(=O)N2CCC(CC2)C(F)(F)F)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C14 compound treatment 0.321 -8.96E-4 -0.07 0.326 0.00723 0.66 0.4133 0.6257 2079495 Maybridge3_007437 Cc1c(C#N)c(Sc2ccccc2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C15 compound treatment 0.327 0.0051 0.41 0.303 -0.0158 -1.43 -0.7213 -0.4844 2079496 Maybridge3_007438 N#Cc1ccc(nc1)N2CCNCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C16 compound treatment 0.343 0.0211 1.7 0.347 0.0282 2.56 3.0139 0.9801 2079497 Maybridge3_007439 CC1=N/C(=C\c2cccs2)/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C17 compound treatment 0.328 0.0061 0.49 0.307 -0.0118 -1.07 -0.4076 -0.3467 2079498 Maybridge3_007440 CSc1nc(N)n(n1)c2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C18 compound treatment 0.319 -0.0029 -0.23 0.315 -0.00377 -0.34 -0.4066 -0.9826 2079499 Maybridge3_007441 COc1ccc(/C=C(\NC(=O)C)/C(=O)O)c(Cl)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C19 compound treatment 0.326 0.0041 0.33 0.312 -0.00677 -0.61 -0.2006 -0.2876 2079500 Maybridge3_007442 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)c3ccccc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C20 compound treatment 0.337 0.0151 1.22 0.338 0.0192 1.75 2.0946 0.9844 2079501 Maybridge3_007443 COc1c(CC(NC(=O)C)C(=O)O)cccc1OCC2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C21 compound treatment 0.312 -0.0099 -0.8 0.315 -0.00377 -0.34 -0.8052 -0.9286 2079502 Maybridge3_007444 Clc1ccc(cc1)C(=O)NC(=N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C22 compound treatment 0.307 -0.0149 -1.2 0.312 -0.00677 -0.61 -1.2824 -0.9517 2079503 Maybridge3_007445 CC(=O)NC(Cc1ccc(C)c(C)c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C23 mock treatment 0.3 -0.0219 -1.76 0.288 -0.0308 -2.79 -3.2215 -0.9754 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 C24 positive control 0.09 -0.232 -18.67 0.088 -0.231 -20.95 -28.0161 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D01 compound treatment 0.328 0.0061 0.49 0.327 0.00823 0.75 0.8761 0.9793 2079504 Maybridge3_007446 Cc1cc(nn1C(C)(C)C)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D02 mock treatment 0.327 0.0051 0.41 0.324 0.00523 0.48 0.6266 0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D03 compound treatment 0.322 1.04E-4 0.01 0.321 0.00223 0.2 0.1493 0.7358 1500332 Maybridge3_007447 O=C(N1CCN(CC1)c2ccc(C#N)cc2)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D04 mock treatment 0.325 0.0031 0.25 0.327 0.00823 0.75 0.7053 0.8949 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D05 compound treatment 0.32 -0.0019 -0.15 0.32 0.00123 0.11 -0.0287 -0.1517 1465476 Maybridge3_007448 Cc1cc(no1)C(=O)NCCN2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D06 mock treatment 0.323 0.0011 0.09 0.32 0.00123 0.11 0.1421 0.9935 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D07 compound treatment 0.354 0.0321 2.59 0.354 0.0352 3.2 4.0896 0.9944 1532915 Maybridge3_007449 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D08 mock treatment 0.331 0.0091 0.73 0.325 0.00623 0.57 0.9186 0.9918 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D09 compound treatment 0.324 0.0021 0.17 0.318 -7.66E-4 -0.07 0.0707 0.3859 1399292 Maybridge3_007450 CN(CCO)c1nc2cc(Cl)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D10 mock treatment 0.32 -0.0019 -0.15 0.316 -0.00277 -0.25 -0.2855 -0.9716 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D11 compound treatment 0.325 0.0031 0.25 0.318 -7.66E-4 -0.07 0.1276 0.4918 1671504 Maybridge3_007451 CCNc1nc2cccnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D12 mock treatment 0.329 0.0071 0.57 0.319 2.34E-4 0.02 0.4196 0.7329 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D13 compound treatment 0.326 0.0041 0.33 0.319 2.34E-4 0.02 0.2487 0.751 2079505 Maybridge3_007452 OC(=O)c1c(F)cccc1I 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D14 mock treatment 0.324 0.0021 0.17 0.316 -0.00277 -0.25 -0.0577 -0.1905 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D15 compound treatment 0.317 -0.0049 -0.39 0.31 -0.00877 -0.8 -0.8414 -0.9475 2079506 Maybridge3_007453 CN(C(=O)C)c1ccc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D16 mock treatment 0.326 0.0041 0.33 0.318 -7.66E-4 -0.07 0.1846 0.5464 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D17 compound treatment 0.318 -0.0039 -0.31 0.312 -0.00677 -0.61 -0.6561 -0.9514 1549638 Maybridge3_007454 CC(C)(C)c1ccc(NC(=O)CSc2ccccn2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D18 mock treatment 0.324 0.0021 0.17 0.313 -0.00577 -0.52 -0.2503 -0.4549 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D19 mock treatment 0.324 0.0021 0.17 0.313 -0.00577 -0.52 -0.2503 -0.4549 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D20 mock treatment 0.326 0.0041 0.33 0.329 0.0102 0.93 0.8906 0.9032 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D21 mock treatment 0.319 -0.0029 -0.23 0.312 -0.00677 -0.61 -0.5991 -0.9121 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D22 mock treatment 0.32 -0.0019 -0.15 0.316 -0.00277 -0.25 -0.2855 -0.9716 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D23 mock treatment 0.299 -0.0229 -1.84 0.293 -0.0258 -2.34 -2.9575 -0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 D24 positive control 0.091 -0.231 -18.59 0.089 -0.23 -20.86 -27.8949 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E01 compound treatment 0.326 0.0041 0.33 0.321 0.00223 0.2 0.3771 0.9725 2079507 Maybridge3_007455 Cc1nc(N)nc(CSc2ccc(Cl)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E02 compound treatment 0.326 0.0041 0.33 0.321 0.00223 0.2 0.3771 0.9725 2079508 Maybridge3_007456 COC(=O)c1sccc1OCc2nnc(o2)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E03 compound treatment 0.315 -0.0069 -0.56 0.316 -0.00277 -0.25 -0.5702 -0.9356 1640995 Maybridge3_007457 CN(CCOC(=O)c1c(F)cccc1Cl)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E04 compound treatment 0.323 0.0011 0.09 0.319 2.34E-4 0.02 0.0779 0.8521 1544150 Maybridge3_007458 CCOC(=O)c1nc(COc2ccccc2Cl)[nH]c(=O)c1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E05 compound treatment 0.318 -0.0039 -0.31 0.307 -0.0118 -1.07 -0.977 -0.8777 1510566 Maybridge3_007459 Nc1nnc(SC2c3ccccc3-c4ccccc24)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E06 compound treatment 0.333 0.0111 0.89 0.332 0.0132 1.2 1.4817 0.9894 2079509 Maybridge3_007460 FC(F)(F)c1cccc(c1)c2csc(n2)c3ccc(nc3)n4cncn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E07 compound treatment 0.316 -0.0059 -0.47 0.313 -0.00577 -0.52 -0.7058 -0.9988 2079510 Maybridge3_007461 Nc1ccccc1SCc2ncc(cc2Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E08 compound treatment 0.331 0.0091 0.73 0.321 0.00223 0.2 0.6618 0.87 2079511 Maybridge3_007462 Cc1nc(c(s1)C(=O)Sc2ccccc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E09 compound treatment 0.314 -0.0079 -0.64 0.3 -0.0188 -1.7 -1.6541 -0.9097 2079512 Maybridge3_007463 COc1ccc(cc1)C(=O)NC(=N)COc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E10 compound treatment 0.354 0.0321 2.59 0.355 0.0362 3.29 4.1537 0.9929 1288279 Maybridge3_007464 CSc1nnc(SCc2cc(=O)oc3cc(O)ccc23)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E11 compound treatment 0.315 -0.0069 -0.56 0.31 -0.00877 -0.8 -0.9553 -0.9845 2079513 Maybridge3_007465 Cc1nc(cs1)C(=N)NC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E12 compound treatment 0.31 -0.0119 -0.96 0.317 -0.00177 -0.16 -0.7907 -0.8141 2079514 Maybridge3_007466 Cc1cccc(c1)/C(=N/O)/N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E13 compound treatment 0.326 0.0041 0.33 0.324 0.00523 0.48 0.5697 0.9843 2079515 Maybridge3_007467 Cc1onc(c1C(=O)NCCOc2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E14 compound treatment 0.303 -0.0189 -1.52 0.303 -0.0158 -1.43 -2.0879 -0.9995 2079516 Maybridge3_007468 Cc1c(C#N)c(Sc2ccccc2N)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E15 compound treatment 0.325 0.0031 0.25 0.32 0.00123 0.11 0.256 0.9345 1605818 Maybridge3_007469 CS(=O)(=O)N1CCN(CC1)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E16 compound treatment 0.322 1.04E-4 0.01 0.316 -0.00277 -0.25 -0.1716 -0.6831 2079517 Maybridge3_007470 CC1=N/C(=C\C=C\c2ccccc2)/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E17 compound treatment 0.31 -0.0119 -0.96 0.304 -0.0148 -1.34 -1.6251 -0.9864 1234727 Maybridge3_007471 Clc1cncc(Cl)c1Sc2ccccc2NC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E18 compound treatment 0.314 -0.0079 -0.64 0.31 -0.00877 -0.8 -1.0122 -0.9938 2079518 Maybridge3_007472 CC(=O)N/C(=C\c1ccc(OC(F)(F)F)cc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E19 compound treatment 0.31 -0.0119 -0.96 0.305 -0.0138 -1.25 -1.5609 -0.9914 2079519 Maybridge3_007473 Cc1nnc(nc1C)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E20 compound treatment 0.318 -0.0039 -0.31 0.305 -0.0138 -1.25 -1.1054 -0.858 2079520 Maybridge3_007474 Cc1c(CC(N)C(=O)O)sc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E21 compound treatment 0.334 0.0121 0.97 0.329 0.0102 0.93 1.3461 0.9997 2079521 Maybridge3_007475 FC(F)(F)c1cccc(c1)C(=O)NC(=N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E22 compound treatment 0.318 -0.0039 -0.31 0.306 -0.0128 -1.16 -1.0412 -0.8673 1615443 Maybridge3_007476 O=S(=O)(N1CCCN(CC1)c2ccc(C#N)cn2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E23 mock treatment 0.296 -0.0259 -2.09 0.291 -0.0278 -2.52 -3.2567 -0.9956 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 E24 positive control 0.094 -0.228 -18.35 0.092 -0.227 -20.58 -27.5315 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F01 compound treatment 0.328 0.0061 0.49 0.323 0.00423 0.38 0.6194 0.9926 2079522 Maybridge3_007477 Cn1c(SCC(=O)c2ccc3OCCOc3c2)nnc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F02 mock treatment 0.328 0.0061 0.49 0.325 0.00623 0.57 0.7477 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F03 compound treatment 0.335 0.0131 1.06 0.333 0.0142 1.29 1.6598 0.9949 1413994 Maybridge3_007478 O=C(N1CCN(CC1)c2nc(ns2)c3cccs3)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F04 mock treatment 0.325 0.0031 0.25 0.327 0.00823 0.75 0.7053 0.8949 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F05 compound treatment 0.328 0.0061 0.49 0.323 0.00423 0.38 0.6194 0.9926 1359456 Maybridge3_007479 O=C(CCn1c(=O)oc2ccccc12)NCCN3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F06 mock treatment 0.328 0.0061 0.49 0.325 0.00623 0.57 0.7477 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F07 compound treatment 0.302 -0.0199 -1.6 0.306 -0.0128 -1.16 -1.9522 -0.9874 1715583 Maybridge3_007480 O=S(=O)(Nc1ccc(cc1)N2CCN(Cc3ccccc3)CC2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F08 mock treatment 0.328 0.0061 0.49 0.325 0.00623 0.57 0.7477 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F09 compound treatment 0.32 -0.0019 -0.15 0.31 -0.00877 -0.8 -0.6706 -0.8277 2079523 Maybridge3_007481 CSc1ncc(c2ccc(Cl)cc2)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F10 mock treatment 0.328 0.0061 0.49 0.328 0.00923 0.84 0.9403 0.9677 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F11 compound treatment 0.317 -0.0049 -0.39 0.318 -7.66E-4 -0.07 -0.3279 -0.8191 1730054 Maybridge3_007482 CC(C)Nc1nc2cccnc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F12 mock treatment 0.33 0.0081 0.65 0.324 0.00523 0.48 0.7974 0.9878 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F13 compound treatment 0.326 0.0041 0.33 0.308 -0.0108 -0.98 -0.4573 -0.4433 2079524 Maybridge3_007483 COC(=O)Nc1ccc(SC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F14 mock treatment 0.323 0.0011 0.09 0.317 -0.00177 -0.16 -0.0505 -0.2753 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F15 compound treatment 0.321 -8.96E-4 -0.07 0.317 -0.00177 -0.16 -0.1643 -0.935 2079525 Maybridge3_007484 CN(C(=O)C)c1ccc(F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F16 mock treatment 0.331 0.0091 0.73 0.325 0.00623 0.57 0.9186 0.9918 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F17 compound treatment 0.32 -0.0019 -0.15 0.323 0.00423 0.38 0.1638 0.3962 2079526 Maybridge3_007485 Cc1ccc(CSc2nnc(N/C=N/O)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F18 mock treatment 0.319 -0.0029 -0.23 0.319 2.34E-4 0.02 -0.1498 -0.64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F19 mock treatment 0.327 0.0051 0.41 0.317 -0.00177 -0.16 0.1773 0.4019 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F20 mock treatment 0.325 0.0031 0.25 0.32 0.00123 0.11 0.256 0.9345 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F21 mock treatment 0.318 -0.0039 -0.31 0.318 -7.66E-4 -0.07 -0.271 -0.8433 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F22 mock treatment 0.318 -0.0039 -0.31 0.312 -0.00677 -0.61 -0.6561 -0.9514 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F23 mock treatment 0.301 -0.0209 -1.68 0.298 -0.0208 -1.88 -2.5227 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 F24 positive control 0.093 -0.229 -18.43 0.092 -0.227 -20.58 -27.5885 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G01 compound treatment 0.332 0.0101 0.81 0.331 0.0122 1.11 1.3606 0.9883 2079527 Maybridge3_007486 Cc1cc(no1)c2nc(COc3ccc(Cl)cc3Cl)no2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G02 compound treatment 0.321 -8.96E-4 -0.07 0.316 -0.00277 -0.25 -0.2285 -0.8749 2079528 Maybridge3_007487 N/C(=N\O)/c1ccc(Oc2c(Cl)cncc2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G03 compound treatment 0.311 -0.0109 -0.88 0.311 -0.00777 -0.7 -1.1189 -0.9941 1227344 Maybridge3_007488 CN(CCOC(=O)c1cc(Cl)cc(Cl)c1)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G04 compound treatment 0.329 0.0071 0.57 0.319 2.34E-4 0.02 0.4196 0.7329 2079529 Maybridge3_007489 FC(F)(F)C1CCN(CC1)C(=O)CSc2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G05 compound treatment 0.315 -0.0069 -0.56 0.303 -0.0158 -1.43 -1.4046 -0.915 2079530 Maybridge3_007490 FC(F)(F)c1cnc(COc2ccc(CC#N)cc2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G06 compound treatment 0.327 0.0051 0.41 0.32 0.00123 0.11 0.3699 0.8682 2079531 Maybridge3_007491 CC(C)(C)c1csc(n1)c2ccc(nc2)n3cncn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G07 compound treatment 0.323 0.0011 0.09 0.32 0.00123 0.11 0.1421 0.9935 2079532 Maybridge3_007492 COc1nccc(c1C(=O)N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G08 compound treatment 0.315 -0.0069 -0.56 0.314 -0.00477 -0.43 -0.6985 -0.9924 2079533 Maybridge3_007493 Cc1ccc(cc1F)C(=N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G09 compound treatment 0.311 -0.0109 -0.88 0.313 -0.00577 -0.52 -0.9905 -0.9695 2079534 Maybridge3_007494 CCOC(=O)c1cc(C#N)c(Sc2ccccc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G10 compound treatment 0.336 0.0141 1.14 0.335 0.0162 1.47 1.8451 0.9917 1537904 Maybridge3_007495 Oc1ccc2c(CSc3nnc(SCC4CC4)s3)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G11 compound treatment 0.315 -0.0069 -0.56 0.309 -0.00977 -0.89 -1.0195 -0.9746 2079535 Maybridge3_007496 CCOC(=O)c1cc(C#N)c(Sc2nnc(SCC3CC3)s2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G12 compound treatment 0.331 0.0091 0.73 0.322 0.00323 0.29 0.726 0.9193 2079536 Maybridge3_007497 CCOC(=O)c1cc(C)nn1Cc2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G13 compound treatment 0.33 0.0081 0.65 0.324 0.00523 0.48 0.7974 0.9878 1580023 Maybridge3_007498 CC(C)(C)C(=O)OCc1nc(cs1)c2cc(no2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G14 compound treatment 0.329 0.0071 0.57 0.325 0.00623 0.57 0.8047 1.0 1312692 Maybridge3_007499 Cc1c(C#N)c(Sc2ccccc2NC(=O)c3ccco3)nc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G15 compound treatment 0.316 -0.0059 -0.47 0.314 -0.00477 -0.43 -0.6416 -0.9989 2079537 Maybridge3_007500 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)Nc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G16 compound treatment 0.326 0.0041 0.33 0.316 -0.00277 -0.25 0.0562 0.1354 2079538 Maybridge3_007501 CC(=O)N/C(=C\C=C\c1ccccc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G17 compound treatment 0.318 -0.0039 -0.31 0.313 -0.00577 -0.52 -0.5919 -0.97 2079539 Maybridge3_007502 CNc1nc(ns1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G18 compound treatment 0.318 -0.0039 -0.31 0.32 0.00123 0.11 -0.1426 -0.4281 2079540 Maybridge3_007503 CC(=O)NC(Cc1ccc2ccccc2c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G19 compound treatment 0.315 -0.0069 -0.56 0.31 -0.00877 -0.8 -0.9553 -0.9845 2079541 Maybridge3_007504 NC(=O)CSc1nnc(s1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G20 compound treatment 0.321 -8.96E-4 -0.07 0.316 -0.00277 -0.25 -0.2285 -0.8749 2079542 Maybridge3_007505 C(Sc1nncn1c2ccc3OCCOc3c2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G21 compound treatment 0.308 -0.0139 -1.12 0.303 -0.0158 -1.43 -1.8032 -0.9926 2079543 Maybridge3_007506 Cc1ccc(cc1)C(=O)NC(=N)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G22 compound treatment 0.333 0.0111 0.89 0.329 0.0102 0.93 1.2892 0.9998 1729507 Maybridge3_007507 CC(C)(C)c1cc(c2nnc(o2)C3CC3)n(Cc4ccc(F)cc4)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G23 mock treatment 0.301 -0.0209 -1.68 0.293 -0.0258 -2.34 -2.8436 -0.9869 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 G24 positive control 0.096 -0.226 -18.19 0.092 -0.227 -20.58 -27.4177 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H01 compound treatment 0.334 0.0121 0.97 0.335 0.0162 1.47 1.7312 0.9799 2079544 Maybridge3_007508 CSc1nnc(SCC(=O)c2ccc3OCCOc3c2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H02 mock treatment 0.328 0.0061 0.49 0.324 0.00523 0.48 0.6835 0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H03 compound treatment 0.33 0.0081 0.65 0.329 0.0102 0.93 1.1184 0.9851 2079545 Maybridge3_007509 Clc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3nc(ns3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H04 mock treatment 0.331 0.0091 0.73 0.329 0.0102 0.93 1.1753 0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H05 compound treatment 0.327 0.0051 0.41 0.324 0.00523 0.48 0.6266 0.9974 2079546 Maybridge3_007510 COC(=O)CNC(=O)c1cc(C)on1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H06 mock treatment 0.325 0.0031 0.25 0.325 0.00623 0.57 0.5769 0.9325 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H07 compound treatment 0.318 -0.0039 -0.31 0.314 -0.00477 -0.43 -0.5277 -0.9875 1559290 Maybridge3_007511 CN1CCN(CC1)c2ccc(NC(=O)c3ccco3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H08 mock treatment 0.321 -8.96E-4 -0.07 0.319 2.34E-4 0.02 -0.036 -0.4783 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H09 compound treatment 0.328 0.0061 0.49 0.321 0.00223 0.2 0.491 0.9233 2079547 Maybridge3_007512 N#C/N=C(\Nc1ccccc1)/Oc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H10 mock treatment 0.318 -0.0039 -0.31 0.316 -0.00277 -0.25 -0.3993 -0.9939 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H11 compound treatment 0.321 -8.96E-4 -0.07 0.313 -0.00577 -0.52 -0.4211 -0.797 1145665 Maybridge3_007513 C(Nc1nc2cccnc2s1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H12 mock treatment 0.321 -8.96E-4 -0.07 0.311 -0.00777 -0.7 -0.5494 -0.7754 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H13 compound treatment 0.34 0.0181 1.46 0.337 0.0182 1.66 2.2012 0.998 2079548 Maybridge3_007514 CC(=O)Nc1ccc(OCc2ccc3ccccc3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H14 mock treatment 0.327 0.0051 0.41 0.321 0.00223 0.2 0.4341 0.947 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H15 compound treatment 0.317 -0.0049 -0.39 0.32 0.00123 0.11 -0.1995 -0.4869 1543399 Maybridge3_007515 CC(C)(C)OC(=O)N1CCC(CC1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H16 mock treatment 0.318 -0.0039 -0.31 0.313 -0.00577 -0.52 -0.5919 -0.97 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H17 compound treatment 0.325 0.0031 0.25 0.324 0.00523 0.48 0.5127 0.955 2079549 Maybridge3_007516 CCCSc1nnc(N/C=N/O)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H18 mock treatment 0.324 0.0021 0.17 0.318 -7.66E-4 -0.07 0.0707 0.3859 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H19 mock treatment 0.335 0.0131 1.06 0.314 -0.00477 -0.43 0.4403 0.3861 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H20 mock treatment 0.325 0.0031 0.25 0.319 2.34E-4 0.02 0.1918 0.7645 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H21 mock treatment 0.321 -8.96E-4 -0.07 0.314 -0.00477 -0.43 -0.3569 -0.8138 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H22 mock treatment 0.323 0.0011 0.09 0.317 -0.00177 -0.16 -0.0505 -0.2753 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H23 mock treatment 0.301 -0.0209 -1.68 0.295 -0.0238 -2.16 -2.7152 -0.9924 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 H24 positive control 0.096 -0.226 -18.19 0.094 -0.225 -20.4 -27.2893 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I01 compound treatment 0.324 0.0021 0.17 0.329 0.0102 0.93 0.7767 0.8225 2079550 Maybridge3_007517 Cc1nn(CCC#N)c(C)c1Sc2ncccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I02 compound treatment 0.327 0.0051 0.41 0.321 0.00223 0.2 0.4341 0.947 2079551 Maybridge3_007518 FC(F)(F)c1ccncc1C(=O)NC(=N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I03 compound treatment 0.329 0.0071 0.57 0.307 -0.0118 -1.07 -0.3507 -0.2894 2079552 Maybridge3_007519 CN(CCOC(=O)c1ccc(OC(F)(F)F)cc1)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I04 compound treatment 0.316 -0.0059 -0.47 0.319 2.34E-4 0.02 -0.3207 -0.6748 2079553 Maybridge3_007520 Cc1ccc(SCC(=O)N2CCC(CC2)C(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I05 compound treatment 0.333 0.0111 0.89 0.336 0.0172 1.56 1.7385 0.9648 2079554 Maybridge3_007521 O/N=C/c1ncc(cc1Sc2ccc(Cl)cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I06 compound treatment 0.324 0.0021 0.17 0.322 0.00323 0.29 0.3274 0.9659 2079555 Maybridge3_007522 C(Sc1nnc(s1)c2cnccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I07 compound treatment 0.318 -0.0039 -0.31 0.313 -0.00577 -0.52 -0.5919 -0.97 1218253 Maybridge3_007523 COc1cc(ccn1)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I08 compound treatment 0.318 -0.0039 -0.31 0.31 -0.00877 -0.8 -0.7845 -0.9172 2079556 Maybridge3_007524 CCOC(=O)c1cnn(c2nc(cs2)c3ccccc3)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I09 compound treatment 0.336 0.0141 1.14 0.316 -0.00277 -0.25 0.6256 0.5378 2079557 Maybridge3_007525 CCOC(=O)c1cc(C#N)c(Nc2ccccc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I10 compound treatment 0.313 -0.0089 -0.72 0.315 -0.00377 -0.34 -0.7482 -0.9427 2079558 Maybridge3_007526 Cc1cc(nn1C(C)(C)C)C(=O)Sc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I11 compound treatment 0.313 -0.0089 -0.72 0.313 -0.00577 -0.52 -0.8766 -0.9881 2079559 Maybridge3_007527 CCOC(=O)c1cc(C#N)c(Sc2nnc(SC)s2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I12 compound treatment 0.336 0.0141 1.14 0.333 0.0142 1.29 1.7167 0.9979 2079560 Maybridge3_007528 CCOC(=O)c1cc(C)n(Cc2cccc(c2)C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I13 compound treatment 0.328 0.0061 0.49 0.332 0.0132 1.2 1.197 0.9222 2079561 Maybridge3_007529 FC(F)(F)COc1ccc(cn1)c2nnc(SCc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I14 compound treatment 0.314 -0.0079 -0.64 0.315 -0.00377 -0.34 -0.6913 -0.9576 1137650 Maybridge3_007530 Cc1cc(nn1Cc2ccc(C)cc2)C(=O)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I15 compound treatment 0.31 -0.0119 -0.96 0.315 -0.00377 -0.34 -0.9191 -0.9036 2079562 Maybridge3_007531 CSc1nnc(o1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I16 compound treatment 0.318 -0.0039 -0.31 0.314 -0.00477 -0.43 -0.5277 -0.9875 2079563 Maybridge3_007532 CC(=O)N/C(=C\c1ccccc1Br)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I17 compound treatment 0.32 -0.0019 -0.15 0.318 -7.66E-4 -0.07 -0.1571 -0.9366 2079564 Maybridge3_007533 Cc1ccc(Sc2nc(ns2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I18 compound treatment 0.338 0.0161 1.3 0.329 0.0102 0.93 1.5739 0.9866 2079565 Maybridge3_007534 CC(=O)N/C(=C\c1cc(F)cc(F)c1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I19 compound treatment 0.34 0.0181 1.46 0.339 0.0202 1.84 2.3296 0.9935 2079566 Maybridge3_007535 C(SC1=NNC(S1)c2ccccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I20 compound treatment 0.338 0.0161 1.3 0.328 0.00923 0.84 1.5097 0.9777 2079567 Maybridge3_007536 CC(C)(C)NC(=O)C1CC2CCCCC2CN1C(=O)c3ccno3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I21 compound treatment 0.324 0.0021 0.17 0.316 -0.00277 -0.25 -0.0577 -0.1905 2079568 Maybridge3_007537 N=C(NC(=O)c1cccs1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I22 compound treatment 0.316 -0.0059 -0.47 0.311 -0.00777 -0.7 -0.8341 -0.9815 2079569 Maybridge3_007538 COc1ccc(CNC(CO)c2ccccc2)c(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I23 mock treatment 0.304 -0.0179 -1.44 0.3 -0.0188 -1.7 -2.2235 -0.9965 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 I24 positive control 0.097 -0.225 -18.11 0.095 -0.224 -20.31 -27.1682 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J01 compound treatment 0.324 0.0021 0.17 0.324 0.00523 0.48 0.4558 0.9036 2079570 Maybridge3_007539 Fc1ccc(SCC(=O)c2ccc3OCCOc3c2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J02 mock treatment 0.33 0.0081 0.65 0.33 0.0112 1.02 1.1825 0.9767 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J03 compound treatment 0.318 -0.0039 -0.31 0.315 -0.00377 -0.34 -0.4635 -0.9991 1695625 Maybridge3_007540 COC(=O)CNC(=O)c1ccncc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J04 mock treatment 0.332 0.0101 0.81 0.325 0.00623 0.57 0.9755 0.9843 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J05 compound treatment 0.321 -8.96E-4 -0.07 0.313 -0.00577 -0.52 -0.4211 -0.797 2079571 Maybridge3_007541 CC(C)(C)OC(=O)N1Cc2ccccc2CC1C(=O)NCCN3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J06 mock treatment 0.327 0.0051 0.41 0.325 0.00623 0.57 0.6908 0.9877 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J07 compound treatment 0.311 -0.0109 -0.88 0.303 -0.0158 -1.43 -1.6323 -0.9724 1431177 Maybridge3_007542 CCc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)N3CCN(C)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J08 mock treatment 0.323 0.0011 0.09 0.325 0.00623 0.57 0.463 0.8083 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J09 compound treatment 0.322 1.04E-4 0.01 0.317 -0.00177 -0.16 -0.1074 -0.6691 2079572 Maybridge3_007543 COc1ccc(N/C(=N/C#N)/Oc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J10 mock treatment 0.307 -0.0149 -1.2 0.315 -0.00377 -0.34 -1.0899 -0.8738 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J11 compound treatment 0.323 0.0011 0.09 0.324 0.00523 0.48 0.3988 0.8251 1640360 Maybridge3_007544 CS(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J12 mock treatment 0.326 0.0041 0.33 0.313 -0.00577 -0.52 -0.1364 -0.2203 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J13 compound treatment 0.313 -0.0089 -0.72 0.318 -7.66E-4 -0.07 -0.5557 -0.7721 2079573 Maybridge3_007545 Nc1ccc(OCc2ccc3ccccc3n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J14 mock treatment 0.328 0.0061 0.49 0.317 -0.00177 -0.16 0.2343 0.4531 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J15 compound treatment 0.317 -0.0049 -0.39 0.309 -0.00977 -0.89 -0.9056 -0.9334 2079574 Maybridge3_007546 Cc1nc(CC(=O)O)c(C)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J16 mock treatment 0.328 0.0061 0.49 0.317 -0.00177 -0.16 0.2343 0.4531 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J17 compound treatment 0.327 0.0051 0.41 0.32 0.00123 0.11 0.3699 0.8682 2079575 Maybridge3_007547 Cc1cnc(N/C=N/O)c(Br)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J18 mock treatment 0.329 0.0071 0.57 0.323 0.00423 0.38 0.6763 0.9813 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J19 mock treatment 0.331 0.0091 0.73 0.318 -7.66E-4 -0.07 0.4693 0.6372 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J20 mock treatment 0.327 0.0051 0.41 0.321 0.00223 0.2 0.4341 0.947 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J21 mock treatment 0.321 -8.96E-4 -0.07 0.319 2.34E-4 0.02 -0.036 -0.4783 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J22 mock treatment 0.321 -8.96E-4 -0.07 0.315 -0.00377 -0.34 -0.2927 -0.8379 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J23 mock treatment 0.298 -0.0239 -1.92 0.295 -0.0238 -2.16 -2.886 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 J24 positive control 0.096 -0.226 -18.19 0.095 -0.224 -20.31 -27.2251 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K01 compound treatment 0.328 0.0061 0.49 0.326 0.00723 0.66 0.8119 0.9898 2079576 Maybridge3_007548 Cc1noc(C)c1C(=O)Sc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K02 compound treatment 0.321 -8.96E-4 -0.07 0.323 0.00423 0.38 0.2208 0.5646 2079577 Maybridge3_007549 COc1cc(OC)nc(SC)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K03 compound treatment 0.344 0.0221 1.78 0.341 0.0222 2.02 2.6857 0.998 2079578 Maybridge3_007550 CSc1nnc(c2cnccc2C(F)(F)F)n1c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K04 compound treatment 0.322 1.04E-4 0.01 0.321 0.00223 0.2 0.1493 0.7358 2079579 Maybridge3_007551 CCOC(=O)c1cc(C)nn1c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K05 compound treatment 0.332 0.0101 0.81 0.327 0.00823 0.75 1.1039 0.9991 2079580 Maybridge3_007552 Cc1cc(no1)c2nnc(SCC(=O)c3ccccc3)n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K06 compound treatment 0.33 0.0081 0.65 0.319 2.34E-4 0.02 0.4765 0.7298 2079581 Maybridge3_007553 O=C(CSc1nnc(s1)c2cnccn2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K07 compound treatment 0.32 -0.0019 -0.15 0.311 -0.00777 -0.7 -0.6064 -0.8407 1221644 Maybridge3_007554 Cc1nc(N)nc(COc2ccccc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K08 compound treatment 0.345 0.0231 1.86 0.339 0.0202 1.84 2.6143 1.0 1489033 Maybridge3_007555 Cc1ccc(SCc2cc(=O)oc3cc(O)ccc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K09 compound treatment 0.318 -0.0039 -0.31 0.307 -0.0118 -1.07 -0.977 -0.8777 2079582 Maybridge3_007556 Cc1cc(no1)C(=O)NC(=N)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K10 compound treatment 0.346 0.0241 1.94 0.342 0.0232 2.11 2.8638 0.9991 1234272 Maybridge3_007557 CCOC(=O)c1cc(Sc2ccccc2)cc(n1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K11 compound treatment 0.318 -0.0039 -0.31 0.317 -0.00177 -0.16 -0.3352 -0.9514 1277094 Maybridge3_007558 O=c1oc2cccnc2n1Cc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K12 compound treatment 0.32 -0.0019 -0.15 0.311 -0.00777 -0.7 -0.6064 -0.8407 2079583 Maybridge3_007559 Cn1nc(cc1C(=O)Nc2ccccc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K13 compound treatment 0.362 0.0401 3.23 0.355 0.0362 3.29 4.6093 1.0 2079584 Maybridge3_007560 Cc1onc(c1C(=O)NC(=N)c2ccc(Cl)cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K14 compound treatment 0.362 0.0401 3.23 0.365 0.0462 4.2 5.2511 0.9916 1136125 Maybridge3_007561 CC(=O)Nc1ccc(SC(=O)c2cc(C)n(Cc3ccc(C)cc3)n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K15 compound treatment 0.337 0.0151 1.22 0.328 0.00923 0.84 1.4528 0.9835 2079585 Maybridge3_007562 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)c3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K16 compound treatment 0.317 -0.0049 -0.39 0.31 -0.00877 -0.8 -0.8414 -0.9475 2079586 Maybridge3_007563 CC(=O)N/C(=C\c1sc2ccccc2c1C)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K17 compound treatment 0.318 -0.0039 -0.31 0.306 -0.0128 -1.16 -1.0412 -0.8673 2079587 Maybridge3_007564 Clc1ccc(Sc2nc(ns2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K18 compound treatment 0.343 0.0211 1.7 0.344 0.0252 2.29 2.8214 0.9892 2079588 Maybridge3_007565 COc1c(OC2CCCC2)cccc1/C=C(\NC(=O)C)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K19 compound treatment 0.339 0.0171 1.38 0.334 0.0152 1.38 1.9517 1.0 2079589 Maybridge3_007566 CSC1=NNC(S1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K20 compound treatment 0.323 0.0011 0.09 0.314 -0.00477 -0.43 -0.243 -0.5502 2079590 Maybridge3_007567 CC(=O)N/C(=C/c1ccc(C)c(C)c1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K21 compound treatment 0.327 0.0051 0.41 0.312 -0.00677 -0.61 -0.1436 -0.1943 2079591 Maybridge3_007568 Oc1nnc(Sc2nc(ns2)c3cccs3)n1c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K22 compound treatment 0.315 -0.0069 -0.56 0.312 -0.00677 -0.61 -0.8269 -0.9987 2079592 Maybridge3_007569 CC(=O)N/C(=C/c1ccoc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K23 mock treatment 0.3 -0.0219 -1.76 0.293 -0.0258 -2.34 -2.9005 -0.9903 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 K24 positive control 0.099 -0.223 -17.95 0.096 -0.223 -20.22 -26.9901 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L01 compound treatment 0.329 0.0071 0.57 0.328 0.00923 0.84 0.9972 0.9827 2079593 Maybridge3_007570 FC(F)(F)c1ccc(SCC(=O)c2ccc3OCCOc3c2)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L02 mock treatment 0.329 0.0071 0.57 0.327 0.00823 0.75 0.933 0.9913 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L03 compound treatment 0.322 1.04E-4 0.01 0.318 -7.66E-4 -0.07 -0.0432 -0.6171 2079594 Maybridge3_007571 COC(=O)CNC(=O)c1nc(SC)ncc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L04 mock treatment 0.33 0.0081 0.65 0.323 0.00423 0.38 0.7332 0.9681 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L05 compound treatment 0.318 -0.0039 -0.31 0.314 -0.00477 -0.43 -0.5277 -0.9875 1191105 Maybridge3_007572 CCOC(=O)C1CCN(Cc2cccc(NC(=O)c3cccs3)c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L06 mock treatment 0.327 0.0051 0.41 0.323 0.00423 0.38 0.5624 0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L07 compound treatment 0.312 -0.0099 -0.8 0.303 -0.0158 -1.43 -1.5754 -0.9618 2079595 Maybridge3_007573 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3cccc(c3)C(F)(F)F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L08 mock treatment 0.323 0.0011 0.09 0.32 0.00123 0.11 0.1421 0.9935 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L09 compound treatment 0.326 0.0041 0.33 0.319 2.34E-4 0.02 0.2487 0.751 2079596 Maybridge3_007574 Nc1nc(Nc2ccccc2)n[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L10 mock treatment 0.327 0.0051 0.41 0.318 -7.66E-4 -0.07 0.2415 0.5793 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L11 compound treatment 0.318 -0.0039 -0.31 0.321 0.00223 0.2 -0.0784 -0.2099 1439307 Maybridge3_007575 CS(=O)(=O)c1ccc(cc1)C(=O)Nc2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L12 mock treatment 0.327 0.0051 0.41 0.315 -0.00377 -0.34 0.0489 0.0915 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L13 compound treatment 0.326 0.0041 0.33 0.322 0.00323 0.29 0.4413 0.9983 2079597 Maybridge3_007576 CCc1cc(Br)ccc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L14 mock treatment 0.324 0.0021 0.17 0.316 -0.00277 -0.25 -0.0577 -0.1905 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L15 compound treatment 0.315 -0.0069 -0.56 0.311 -0.00777 -0.7 -0.8911 -0.993 2079598 Maybridge3_007577 Cc1onc(c1N)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L16 mock treatment 0.329 0.0071 0.57 0.322 0.00323 0.29 0.6121 0.9519 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L17 compound treatment 0.319 -0.0029 -0.23 0.321 0.00223 0.2 -0.0215 -0.0695 2079599 Maybridge3_007578 Cc1nc(N/C=N/O)ccc1Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L18 mock treatment 0.329 0.0071 0.57 0.323 0.00423 0.38 0.6763 0.9813 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L19 mock treatment 0.32 -0.0019 -0.15 0.318 -7.66E-4 -0.07 -0.1571 -0.9366 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L20 mock treatment 0.329 0.0071 0.57 0.325 0.00623 0.57 0.8047 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L21 mock treatment 0.323 0.0011 0.09 0.316 -0.00277 -0.25 -0.1146 -0.4304 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L22 mock treatment 0.322 1.04E-4 0.01 0.32 0.00123 0.11 0.0852 0.758 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L23 mock treatment 0.304 -0.0179 -1.44 0.301 -0.0178 -1.61 -2.1593 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 L24 positive control 0.098 -0.224 -18.03 0.096 -0.223 -20.22 -27.047 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M01 compound treatment 0.325 0.0031 0.25 0.324 0.00523 0.48 0.5127 0.955 2079600 Maybridge3_007579 COC(=O)c1c(C)n[nH]c1COc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M02 compound treatment 0.321 -8.96E-4 -0.07 0.319 2.34E-4 0.02 -0.036 -0.4783 1564453 Maybridge3_007580 Clc1ccc(SC(=O)N2CCOCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M03 compound treatment 0.344 0.0221 1.78 0.336 0.0172 1.56 2.3648 0.9979 2079601 Maybridge3_007581 CSc1nc(CSc2ccccc2)nc(N)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M04 compound treatment 0.323 0.0011 0.09 0.316 -0.00277 -0.25 -0.1146 -0.4304 2079602 Maybridge3_007582 CSc1nnc(SCC(=O)N2CCC(CC2)C(F)(F)F)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M05 compound treatment 0.323 0.0011 0.09 0.322 0.00323 0.29 0.2705 0.8817 2079603 Maybridge3_007583 CCOC(=O)c1cc(C)nc(Sc2ccccc2Cl)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M06 compound treatment 0.323 0.0011 0.09 0.321 0.00223 0.2 0.2063 0.9315 2079604 Maybridge3_007584 FC(F)(F)c1cccc(c1)C(=O)CSc2nnc(s2)c3cnccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M07 compound treatment 0.318 -0.0039 -0.31 0.313 -0.00577 -0.52 -0.5919 -0.97 1074960 Maybridge3_007585 CCOC(=O)c1cnc(C)nc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M08 compound treatment 0.342 0.0201 1.62 0.336 0.0172 1.56 2.2509 0.9999 1648201 Maybridge3_007586 Oc1ccc2c(CSc3ccccc3)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M09 compound treatment 0.311 -0.0109 -0.88 0.31 -0.00877 -0.8 -1.183 -0.9988 2079605 Maybridge3_007587 CCOC(=O)c1cc(C#N)c(Oc2ccccc2)nc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M10 compound treatment 0.324 0.0021 0.17 0.313 -0.00577 -0.52 -0.2503 -0.4549 1331589 Maybridge3_007588 CCOC(=O)c1cc(Sc2ccccc2N)cc(n1)C(=O)OCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M11 compound treatment 0.327 0.0051 0.41 0.321 0.00223 0.2 0.4341 0.947 1554021 Maybridge3_007589 CC(C)c1ccc(NC(=O)Cn2c(=O)oc3cccnc23)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M12 compound treatment 0.33 0.0081 0.65 0.325 0.00623 0.57 0.8616 0.9975 2079606 Maybridge3_007590 Cn1nc(cc1C(=O)Oc2ccc(Cl)cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M13 compound treatment 0.327 0.0051 0.41 0.32 0.00123 0.11 0.3699 0.8682 2079607 Maybridge3_007591 FC(F)(F)c1cccc(n1)c2nnc(SCc3ccccc3)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M14 compound treatment 0.343 0.0211 1.7 0.345 0.0262 2.38 2.8855 0.9863 2079608 Maybridge3_007592 CSc1nnc(C)n1c2ccc(OCc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M15 compound treatment 0.318 -0.0039 -0.31 0.314 -0.00477 -0.43 -0.5277 -0.9875 1642418 Maybridge3_007593 Clc1cncc(Cl)c1N2CCN(CC2)C(=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M16 compound treatment 0.324 0.0021 0.17 0.319 2.34E-4 0.02 0.1349 0.7896 2079609 Maybridge3_007594 CC(=O)N/C(=C\c1ccc(C#N)cc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M17 compound treatment 0.329 0.0071 0.57 0.322 0.00323 0.29 0.6121 0.9519 2079610 Maybridge3_007595 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)Nc3ccccc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M18 compound treatment 0.32 -0.0019 -0.15 0.316 -0.00277 -0.25 -0.2855 -0.9716 2079611 Maybridge3_007596 CC(C)Oc1ccc(/C=C(\NC(=O)C)/C(=O)O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M19 compound treatment 0.361 0.0391 3.15 0.346 0.0272 2.47 3.9747 0.9928 2079612 Maybridge3_007597 CC(C)(C)C(=O)CSC1=NNC(S1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M20 compound treatment 0.337 0.0151 1.22 0.33 0.0112 1.02 1.5811 0.9962 2079613 Maybridge3_007598 CC(=O)N/C(=C/c1ccc2OCOc2c1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M21 compound treatment 0.411 0.0891 7.18 0.412 0.0932 8.46 11.0579 0.9966 2079614 Maybridge3_007599 Cn1cc(Cl)c(n1)C2NN=C(SCC(=O)c3ccc(Cl)cc3)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M22 compound treatment 0.317 -0.0049 -0.39 0.313 -0.00577 -0.52 -0.6488 -0.9902 2079615 Maybridge3_007600 COc1ccc(OCCNC(=O)c2ccco2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M23 mock treatment 0.302 -0.0199 -1.6 0.293 -0.0258 -2.34 -2.7867 -0.983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 M24 positive control 0.098 -0.224 -18.03 0.096 -0.223 -20.22 -27.047 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N01 compound treatment 0.331 0.0091 0.73 0.347 0.0282 2.56 2.3306 0.8743 2079616 Maybridge3_007601 CSc1nnc(o1)c2ccc(cc2)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N02 mock treatment 0.328 0.0061 0.49 0.329 0.0102 0.93 1.0045 0.9557 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N03 compound treatment 0.334 0.0121 0.97 0.337 0.0182 1.66 1.8596 0.9681 1721449 Maybridge3_007602 Cc1ccc(NC(=O)c2nsc(Cl)c2Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N04 mock treatment 0.321 -8.96E-4 -0.07 0.322 0.00323 0.29 0.1566 0.518 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N05 compound treatment 0.322 1.04E-4 0.01 0.317 -0.00177 -0.16 -0.1074 -0.6691 1670228 Maybridge3_007603 CCOC(=O)C1CCN(Cc2cccc(NC(=O)c3ccco3)c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N06 mock treatment 0.328 0.0061 0.49 0.325 0.00623 0.57 0.7477 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N07 compound treatment 0.318 -0.0039 -0.31 0.313 -0.00577 -0.52 -0.5919 -0.97 2079617 Maybridge3_007604 C/C=C/C(=O)Nc1ccc(cc1)N2CCN(C)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N08 mock treatment 0.325 0.0031 0.25 0.319 2.34E-4 0.02 0.1918 0.7645 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N09 compound treatment 0.317 -0.0049 -0.39 0.316 -0.00277 -0.25 -0.4563 -0.9763 2079618 Maybridge3_007605 COc1ccc(Nc2n[nH]c(N)n2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N10 mock treatment 0.325 0.0031 0.25 0.322 0.00323 0.29 0.3844 0.9968 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N11 compound treatment 0.327 0.0051 0.41 0.319 2.34E-4 0.02 0.3057 0.7427 1178377 Maybridge3_007606 CC(C)c1ccc(Nc2nc3cccnc3s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N12 mock treatment 0.326 0.0041 0.33 0.322 0.00323 0.29 0.4413 0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N13 compound treatment 0.326 0.0041 0.33 0.326 0.00723 0.66 0.698 0.9495 2079619 Maybridge3_007607 CC(=O)Nc1cccc(c1)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N14 mock treatment 0.327 0.0051 0.41 0.322 0.00323 0.29 0.4982 0.9864 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N15 compound treatment 0.317 -0.0049 -0.39 0.306 -0.0128 -1.16 -1.0981 -0.8972 2079620 Maybridge3_007608 CC(C(=O)c1ccc(C)c(Cl)c1)S(=O)(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N16 mock treatment 0.328 0.0061 0.49 0.316 -0.00277 -0.25 0.1701 0.3081 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N17 compound treatment 0.317 -0.0049 -0.39 0.318 -7.66E-4 -0.07 -0.3279 -0.8191 2079621 Maybridge3_007609 O/N=C/Nc1nnc(Cc2ccc(F)cc2)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N18 mock treatment 0.325 0.0031 0.25 0.316 -0.00277 -0.25 -8.0E-4 -0.0021 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N19 mock treatment 0.321 -8.96E-4 -0.07 0.312 -0.00677 -0.61 -0.4853 -0.7848 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N20 mock treatment 0.32 -0.0019 -0.15 0.319 2.34E-4 0.02 -0.0929 -0.6028 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N21 mock treatment 0.329 0.0071 0.57 0.321 0.00223 0.2 0.5479 0.9027 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N22 mock treatment 0.32 -0.0019 -0.15 0.314 -0.00477 -0.43 -0.4138 -0.9021 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N23 mock treatment 0.306 -0.0159 -1.28 0.3 -0.0188 -1.7 -2.1096 -0.9901 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 N24 positive control 0.097 -0.225 -18.11 0.097 -0.222 -20.13 -27.0398 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O01 compound treatment 0.339 0.0171 1.38 0.337 0.0182 1.66 2.1443 0.9958 2079622 Maybridge3_007610 Cc1noc(COc2ccccc2)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O02 compound treatment 0.332 0.0101 0.81 0.328 0.00923 0.84 1.1681 0.9999 1178194 Maybridge3_007611 Cc1ccc(SC(=O)N2CCOCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O03 compound treatment 0.323 0.0011 0.09 0.322 0.00323 0.29 0.2705 0.8817 1301871 Maybridge3_007612 CN(CCOC(=O)Nc1ccccc1)c2ccc(C#N)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O04 compound treatment 0.326 0.0041 0.33 0.33 0.0112 1.02 0.9548 0.8907 2079623 Maybridge3_007613 FC(F)(F)C1CCN(CC1)C(=O)CSc2nnc(SCC3CC3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O05 compound treatment 0.328 0.0061 0.49 0.333 0.0142 1.29 1.2612 0.9123 2079624 Maybridge3_007614 CCOC(=O)c1cc(C)nc(Sc2ccc(NC(=O)C)cc2)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O06 compound treatment 0.327 0.0051 0.41 0.327 0.00823 0.75 0.8192 0.9603 2079625 Maybridge3_007615 O=C(CSc1nnc(s1)c2cnccn2)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O07 compound treatment 0.323 0.0011 0.09 0.318 -7.66E-4 -0.07 0.0137 0.1217 2079626 Maybridge3_007616 COC(=O)c1cc(C)nc(Sc2ccccc2N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O08 compound treatment 0.348 0.0261 2.1 0.346 0.0272 2.47 3.2344 0.9967 2079627 Maybridge3_007617 Oc1ccc2c(CSc3nnc([nH]3)c4ccccc4)cc(=O)oc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O09 compound treatment 0.325 0.0031 0.25 0.323 0.00423 0.38 0.4485 0.9783 2079628 Maybridge3_007618 FC(F)(F)c1cccc(n1)C(=O)Oc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O10 compound treatment 0.319 -0.0029 -0.23 0.312 -0.00677 -0.61 -0.5991 -0.9121 2079629 Maybridge3_007619 Clc1cncc(Cl)c1Oc2ccc(CC#N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O11 compound treatment 0.321 -8.96E-4 -0.07 0.308 -0.0108 -0.98 -0.742 -0.7572 1363260 Maybridge3_007620 CSc1cccc(NC(=O)Cn2nc(C)c(Oc3ccccc3)c2C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O12 compound treatment 0.334 0.0121 0.97 0.331 0.0122 1.11 1.4745 0.9979 2079630 Maybridge3_007621 Cn1nc(cc1C(=O)Oc2ccc(cc2)C(F)(F)F)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O13 compound treatment 0.332 0.0101 0.81 0.327 0.00823 0.75 1.1039 0.9991 2079631 Maybridge3_007622 Clc1ccc(cc1)C(=N)NC(=O)CCn2c(=O)oc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O14 compound treatment 0.319 -0.0029 -0.23 0.32 0.00123 0.11 -0.0857 -0.3311 2079632 Maybridge3_007623 Cc1cc(nn1C(C)(C)C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O15 compound treatment 0.321 -8.96E-4 -0.07 0.32 0.00123 0.11 0.0282 0.2118 2079633 Maybridge3_007624 FC(F)(F)Oc1ccccc1S(=O)(=O)N2CCN(CC2)c3c(Cl)cncc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O16 compound treatment 0.341 0.0191 1.54 0.338 0.0192 1.75 2.3224 0.998 2079634 Maybridge3_007625 CC(=O)Nc1ccc(/C=C/2\N=C(C)OC2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O17 compound treatment 0.325 0.0031 0.25 0.323 0.00423 0.38 0.4485 0.9783 2079635 Maybridge3_007626 FC(F)(F)c1ccc(nc1)c2nnc(SCc3ccc(Cl)cc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O18 compound treatment 0.334 0.0121 0.97 0.337 0.0182 1.66 1.8596 0.9681 2079636 Maybridge3_007627 CC(=O)N/C(=C\c1c[nH]c(n1)c2ccccc2)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O19 compound treatment 0.339 0.0171 1.38 0.355 0.0362 3.29 3.2996 0.9254 2079637 Maybridge3_007628 O=C(CSC1=NNC(S1)c2ccccn2)Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O20 compound treatment 0.331 0.0091 0.73 0.324 0.00523 0.48 0.8544 0.9779 2079638 Maybridge3_007629 CC(=O)N/C(=C/c1ccc(Br)cc1)/C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O21 compound treatment 0.332 0.0101 0.81 0.326 0.00723 0.66 1.0397 0.9943 2079639 Maybridge3_007630 Cn1cc(Cl)c(n1)C2NN=C(SCC(=O)Nc3ccccc3)S2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O22 compound treatment 0.322 1.04E-4 0.01 0.326 0.00723 0.66 0.4703 0.7161 1264644 Maybridge3_007631 Cc1cccc(Cn2nc(cc2C(=O)N3CCOCC3)C(C)(C)C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O23 mock treatment 0.31 -0.0119 -0.96 0.307 -0.0118 -1.07 -1.4325 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 O24 positive control 0.1 -0.222 -17.87 0.097 -0.222 -20.13 -26.869 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P01 compound treatment 0.326 0.0041 0.33 0.329 0.0102 0.93 0.8906 0.9032 1194786 Maybridge3_007632 CCOC(=O)c1sc(COc2ccccc2OC)nc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P02 mock treatment 0.322 1.04E-4 0.01 0.321 0.00223 0.2 0.1493 0.7358 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P03 compound treatment 0.301 -0.0209 -1.68 0.3 -0.0188 -1.7 -2.3943 -1.0 1177413 Maybridge3_007633 COC(=O)C1CCc2ccccc2N1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P04 mock treatment 0.319 -0.0029 -0.23 0.319 2.34E-4 0.02 -0.1498 -0.64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P05 compound treatment 0.325 0.0031 0.25 0.327 0.00823 0.75 0.7053 0.8949 2079640 Maybridge3_007634 CC(C)(C)OC(=O)N1Cc2ccccc2CC1C(=O)NCc3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P06 mock treatment 0.323 0.0011 0.09 0.324 0.00523 0.48 0.3988 0.8251 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P07 compound treatment 0.323 0.0011 0.09 0.323 0.00423 0.38 0.3347 0.8483 1326648 Maybridge3_007635 CCOc1cc(c(OCC)cc1N2CCOCC2)n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P08 mock treatment 0.32 -0.0019 -0.15 0.324 0.00523 0.48 0.228 0.4569 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P09 compound treatment 0.318 -0.0039 -0.31 0.322 0.00323 0.29 -0.0142 -0.0331 2079641 Maybridge3_007636 c1ccn(c1)c2nc3cccnc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P10 mock treatment 0.319 -0.0029 -0.23 0.318 -7.66E-4 -0.07 -0.214 -0.8796 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P11 compound treatment 0.311 -0.0109 -0.88 0.311 -0.00777 -0.7 -1.1189 -0.9941 2079642 Maybridge3_007637 O=C1/C(=C/c2ccccc2)/CCc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P12 mock treatment 0.317 -0.0049 -0.39 0.318 -7.66E-4 -0.07 -0.3279 -0.8191 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P13 compound treatment 0.324 0.0021 0.17 0.319 2.34E-4 0.02 0.1349 0.7896 2079643 Maybridge3_007638 C=C(CC(=O)N1CCOCC1)C(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P14 mock treatment 0.322 1.04E-4 0.01 0.322 0.00323 0.29 0.2135 0.727 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P15 compound treatment 0.322 1.04E-4 0.01 0.324 0.00523 0.48 0.3419 0.7195 2079644 Maybridge3_007639 OC(=O)/C=C/C(=O)c1ccc(cc1)C2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P16 mock treatment 0.32 -0.0019 -0.15 0.32 0.00123 0.11 -0.0287 -0.1517 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P17 mock treatment 0.322 1.04E-4 0.01 0.321 0.00223 0.2 0.1493 0.7358 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P18 mock treatment 0.314 -0.0079 -0.64 0.313 -0.00577 -0.52 -0.8197 -0.9953 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P19 mock treatment 0.317 -0.0049 -0.39 0.316 -0.00277 -0.25 -0.4563 -0.9763 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P20 mock treatment 0.318 -0.0039 -0.31 0.319 2.34E-4 0.02 -0.2068 -0.6577 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P21 mock treatment 0.32 -0.0019 -0.15 0.319 2.34E-4 0.02 -0.0929 -0.6028 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P22 mock treatment 0.318 -0.0039 -0.31 0.32 0.00123 0.11 -0.1426 -0.4281 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P23 mock treatment 0.309 -0.0129 -1.04 0.306 -0.0128 -1.16 -1.5537 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1452 P24 positive control 0.102 -0.22 -17.71 0.098 -0.221 -20.04 -26.6909 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A01 compound treatment 0.305 -0.0106 -0.85 0.312 -0.0115 -1.05 -1.3425 -0.9948 1965040 CMLD1_000001 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A02 compound treatment 0.327 0.0114 0.92 0.333 0.00947 0.86 1.258 0.9994 1965041 CMLD1_000002 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A03 compound treatment 0.297 -0.0186 -1.5 0.312 -0.0115 -1.05 -1.7981 -0.9847 1965042 CMLD1_000003 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A04 compound treatment 0.332 0.0164 1.32 0.338 0.0145 1.31 1.8637 1.0 1965043 CMLD1_000004 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A05 compound treatment 0.314 -0.00158 -0.13 0.328 0.00447 0.41 0.1969 0.4627 1965044 CMLD1_000005 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A06 compound treatment 0.33 0.0144 1.16 0.343 0.0195 1.77 2.0707 0.9792 1965045 CMLD1_000006 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A07 compound treatment 0.313 -0.00258 -0.21 0.309 -0.0145 -1.32 -1.0796 -0.8087 1965046 CMLD1_000007 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A08 compound treatment 0.319 0.00342 0.28 0.344 0.0205 1.86 1.5086 0.803 1965047 CMLD1_000008 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A09 compound treatment 0.314 -0.00158 -0.13 0.332 0.00847 0.77 0.4536 0.5819 1965048 CMLD1_000009 CCCCC=C[C@@H](NC(=O)Oc1cccc(c1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A10 compound treatment 0.321 0.00542 0.44 0.334 0.0105 0.95 0.9806 0.9376 1965049 CMLD1_000010 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(OC)cc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A11 compound treatment 0.299 -0.0166 -1.34 0.317 -0.00653 -0.59 -1.3633 -0.9331 1965050 CMLD1_000011 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3cccs3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A12 compound treatment 0.336 0.0204 1.64 0.344 0.0205 1.86 2.4766 0.9981 1965051 CMLD1_000012 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A13 compound treatment 0.318 0.00242 0.19 0.348 0.0245 2.22 1.7084 0.7661 1965052 CMLD1_000013 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A14 compound treatment 0.329 0.0134 1.08 0.36 0.0365 3.31 3.1049 0.8916 1965053 CMLD1_000014 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A15 compound treatment 0.297 -0.0186 -1.5 0.314 -0.00953 -0.86 -1.6697 -0.966 1965054 CMLD1_000015 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A16 compound treatment 0.327 0.0114 0.92 0.339 0.0155 1.4 1.6432 0.9789 1965055 CMLD1_000016 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A17 compound treatment 0.314 -0.00158 -0.13 0.325 0.00147 0.13 0.0043 0.0235 1965056 CMLD1_000017 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)C(C)(C)C)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A18 compound treatment 0.328 0.0124 1.0 0.334 0.0105 0.95 1.3792 0.9997 1965057 CMLD1_000018 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A19 compound treatment 0.295 -0.0206 -1.66 0.306 -0.0175 -1.59 -2.2971 -0.9998 1965058 CMLD1_000019 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A20 compound treatment 0.332 0.0164 1.32 0.335 0.0115 1.04 1.6711 0.993 1965059 CMLD1_000020 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A21 compound treatment 0.294 -0.0216 -1.74 0.307 -0.0165 -1.5 -2.2898 -0.9973 1965060 CMLD1_000021 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A22 mock treatment 0.301 -0.0146 -1.17 0.31 -0.0135 -1.23 -1.6987 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A23 mock treatment 0.303 -0.0126 -1.01 0.31 -0.0135 -1.23 -1.5848 -0.9954 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 A24 positive control 0.081 -0.235 -18.89 0.086 -0.238 -21.56 -28.6031 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B01 compound treatment 0.356 0.0404 3.25 0.357 0.0335 3.04 4.4498 0.9994 1965061 CMLD1_000022 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B02 compound treatment 0.347 0.0314 2.53 0.36 0.0365 3.31 4.1299 0.9912 1965062 CMLD1_000023 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B03 compound treatment 0.332 0.0164 1.32 0.337 0.0135 1.22 1.7995 0.9992 1965063 CMLD1_000024 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B04 compound treatment 0.324 0.00842 0.68 0.339 0.0155 1.4 1.4723 0.9442 1965064 CMLD1_000025 CCOC(=O)N(CC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4)S(=O)(=O)c6ccc(C)cc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B05 compound treatment 0.333 0.0174 1.4 0.345 0.0215 1.95 2.3699 0.987 1965065 CMLD1_000026 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B06 compound treatment 0.298 -0.0176 -1.42 0.328 0.00447 0.41 -0.7142 -0.4848 1965066 CMLD1_000027 CC(NP(=O)(c1ccccc1)c2ccccc2)C3(CC(=C)c4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B07 compound treatment 0.353 0.0374 3.01 0.36 0.0365 3.31 4.4715 0.9989 1965067 CMLD1_000028 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B08 compound treatment 0.315 -5.83E-4 -0.05 0.328 0.00447 0.41 0.2538 0.6211 1965068 CMLD1_000029 COC(=O)C1(C)NCC2=C(C)C(=O)C(C)C2=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B09 compound treatment 0.324 0.00842 0.68 0.361 0.0375 3.4 2.8844 0.8317 1965069 CMLD1_000030 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B10 compound treatment 0.327 0.0114 0.92 0.337 0.0135 1.22 1.5148 0.9901 1965070 CMLD1_000031 COC(=O)C1(Cc2ccccc2)NCC3=C(C(C)C)C(=O)C(C)C3=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B11 compound treatment 0.334 0.0184 1.48 0.365 0.0415 3.76 3.7106 0.9171 1965071 CMLD1_000032 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B12 compound treatment 0.34 0.0244 1.97 0.356 0.0325 2.95 3.4745 0.9806 1965072 CMLD1_000033 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCc5ccc(Cl)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B13 compound treatment 0.338 0.0224 1.81 0.35 0.0265 2.4 2.9755 0.9901 1965073 CMLD1_000034 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B14 compound treatment 0.345 0.0294 2.37 0.356 0.0325 2.95 3.7592 0.9941 1965074 CMLD1_000035 COc1ccc(COC2OC[C@]3(C)[C@@H]4[C@H]2CCC5C(CO)C(CO)[C@@H](C)C(=C54)CN3C(=O)OC(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B15 compound treatment 0.354 0.0384 3.09 0.357 0.0335 3.04 4.3359 1.0 1965075 CMLD1_000036 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B16 compound treatment 0.33 0.0144 1.16 0.355 0.0315 2.86 2.8409 0.9213 1965076 CMLD1_000037 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(F)cc5)C=C21)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B17 compound treatment 0.347 0.0314 2.53 0.351 0.0275 2.49 3.5522 1.0 1965077 CMLD1_000038 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B18 compound treatment 0.354 0.0384 3.09 0.363 0.0395 3.58 4.721 0.9973 1965078 CMLD1_000039 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B19 compound treatment 0.317 0.00142 0.11 0.327 0.00347 0.32 0.3035 0.9056 1965079 CMLD1_000040 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B20 compound treatment 0.354 0.0384 3.09 0.366 0.0425 3.86 4.9136 0.994 1965080 CMLD1_000041 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B21 compound treatment 0.356 0.0404 3.25 0.367 0.0435 3.95 5.0916 0.9954 1965081 CMLD1_000042 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B22 mock treatment 0.315 -5.83E-4 -0.05 0.324 4.72E-4 0.04 -0.0029 -0.0457 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B23 mock treatment 0.318 0.00242 0.19 0.326 0.00247 0.22 0.2963 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 B24 positive control 0.082 -0.234 -18.81 0.09 -0.234 -21.2 -28.2894 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C01 compound treatment 0.316 4.17E-4 0.03 0.331 0.00747 0.68 0.5033 0.7412 1965082 CMLD1_000043 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC1(CCC2CC1=O)C2(C)C)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C02 compound treatment 0.329 0.0134 1.08 0.334 0.0105 0.95 1.4361 0.998 1965083 CMLD1_000044 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C03 compound treatment 0.31 -0.00558 -0.45 0.333 0.00947 0.86 0.2901 0.2989 1965084 CMLD1_000045 CCCC=C(CCC)[C@@H](NC(=O)CCc1ccccc1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C04 compound treatment 0.332 0.0164 1.32 0.329 0.00547 0.5 1.286 0.9106 1965085 CMLD1_000046 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C05 compound treatment 0.298 -0.0176 -1.42 0.319 -0.00453 -0.41 -1.2918 -0.8762 1965086 CMLD1_000047 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C06 compound treatment 0.341 0.0254 2.05 0.339 0.0155 1.4 2.4403 0.9831 1965087 CMLD1_000048 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C07 compound treatment 0.291 -0.0246 -1.98 0.307 -0.0165 -1.5 -2.4606 -0.9906 1965088 CMLD1_000049 CCCCC=C[C@@H](NC(=O)CCc1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C08 compound treatment 0.337 0.0214 1.72 0.337 0.0135 1.22 2.0842 0.9858 1965089 CMLD1_000050 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(C)onc6c7ccccc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C09 compound treatment 0.291 -0.0246 -1.98 0.302 -0.0215 -1.95 -2.7816 -1.0 1965090 CMLD1_000051 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C10 compound treatment 0.336 0.0204 1.64 0.353 0.0295 2.68 3.0542 0.9727 1965091 CMLD1_000052 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C11 compound treatment 0.299 -0.0166 -1.34 0.312 -0.0115 -1.05 -1.6842 -0.9927 1965092 CMLD1_000053 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccccc3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C12 compound treatment 0.333 0.0174 1.4 0.329 0.00547 0.5 1.343 0.9026 1965093 CMLD1_000054 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C13 compound treatment 0.334 0.0184 1.48 0.364 0.0405 3.67 3.6464 0.9204 1965094 CMLD1_000055 CCCCC=C[C@@H](NC(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C14 compound treatment 0.337 0.0214 1.72 0.345 0.0215 1.95 2.5977 0.9981 1965095 CMLD1_000056 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C15 compound treatment 0.303 -0.0126 -1.01 0.314 -0.00953 -0.86 -1.328 -0.9969 1965096 CMLD1_000057 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C16 compound treatment 0.334 0.0184 1.48 0.339 0.0155 1.4 2.0417 0.9996 1965097 CMLD1_000058 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C17 compound treatment 0.322 0.00642 0.52 0.336 0.0125 1.13 1.1659 0.9369 1965098 CMLD1_000059 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NS(=O)(=O)c3cccc4cccnc34)c5ccc(cc5)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C18 compound treatment 0.335 0.0194 1.56 0.349 0.0255 2.31 2.7405 0.9819 1965099 CMLD1_000060 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(OC)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C19 compound treatment 0.289 -0.0266 -2.14 0.306 -0.0175 -1.59 -2.6387 -0.9893 1965100 CMLD1_000061 CC(C)(C)C(=O)N[C@@H](c1ccc(Cl)cc1)[C@]2(C)C[C@H]2C3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C20 compound treatment 0.339 0.0234 1.89 0.357 0.0335 3.04 3.4818 0.9737 1965101 CMLD1_000062 CCCCC=C[C@@H](NC(=O)OCC#C)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C21 compound treatment 0.318 0.00242 0.19 0.325 0.00147 0.13 0.2321 0.9832 1965060 CMLD1_000063 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C22 mock treatment 0.304 -0.0116 -0.93 0.316 -0.00753 -0.68 -1.1427 -0.9883 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C23 mock treatment 0.303 -0.0126 -1.01 0.311 -0.0125 -1.14 -1.5206 -0.9983 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 C24 positive control 0.082 -0.234 -18.81 0.097 -0.227 -20.56 -27.8401 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D01 compound treatment 0.353 0.0374 3.01 0.369 0.0455 4.13 5.0492 0.988 1965102 CMLD1_000064 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D02 compound treatment 0.353 0.0374 3.01 0.358 0.0345 3.13 4.3431 0.9998 1965103 CMLD1_000065 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D03 compound treatment 0.346 0.0304 2.45 0.364 0.0405 3.67 4.3297 0.9806 1965104 CMLD1_000066 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D04 compound treatment 0.304 -0.0116 -0.93 0.332 0.00847 0.77 -0.1158 -0.0958 1965105 CMLD1_000067 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D05 compound treatment 0.323 0.00742 0.6 0.344 0.0205 1.86 1.7363 0.8896 1965106 CMLD1_000068 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D06 compound treatment 0.312 -0.00358 -0.29 0.325 0.00147 0.13 -0.1095 -0.3445 1965107 CMLD1_000069 CC(=O)N1CC2(CC2)CC1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D07 compound treatment 0.331 0.0154 1.24 0.329 0.00547 0.5 1.2291 0.9192 1965108 CMLD1_000070 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D08 compound treatment 0.31 -0.00558 -0.45 0.335 0.0115 1.04 0.4184 0.3689 1965109 CMLD1_000071 COC(=O)C1(C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D09 compound treatment 0.353 0.0374 3.01 0.354 0.0305 2.77 4.0864 0.9991 1965110 CMLD1_000072 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCn7cc(nc7C)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D10 compound treatment 0.329 0.0134 1.08 0.341 0.0175 1.59 1.8854 0.9825 1965111 CMLD1_000073 COC(=O)C1(Cc2ccccc2)NCC3=C(C(=O)C(C)C3=C1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D11 compound treatment 0.352 0.0364 2.93 0.349 0.0255 2.31 3.7085 0.9931 1965112 CMLD1_000074 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D12 compound treatment 0.344 0.0284 2.29 0.352 0.0285 2.58 3.4456 0.9982 1965113 CMLD1_000075 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccco5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D13 compound treatment 0.347 0.0314 2.53 0.364 0.0405 3.67 4.3866 0.9834 1965057 CMLD1_000076 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D14 compound treatment 0.345 0.0294 2.37 0.356 0.0325 2.95 3.7592 0.9941 1965114 CMLD1_000077 C[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D15 compound treatment 0.359 0.0434 3.5 0.345 0.0215 1.95 3.8504 0.9619 1965115 CMLD1_000078 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D16 compound treatment 0.318 0.00242 0.19 0.328 0.00447 0.41 0.4247 0.9433 1965116 CMLD1_000079 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(F)cc6)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D17 compound treatment 0.357 0.0414 3.34 0.355 0.0315 2.86 4.3783 0.997 1965117 CMLD1_000080 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D18 compound treatment 0.354 0.0384 3.09 0.354 0.0305 2.77 4.1433 0.9984 1965118 CMLD1_000081 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D19 compound treatment 0.362 0.0464 3.74 0.364 0.0405 3.67 5.2407 1.0 1965119 CMLD1_000082 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D20 compound treatment 0.318 0.00242 0.19 0.327 0.00347 0.32 0.3605 0.9732 1965120 CMLD1_000083 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D21 compound treatment 0.358 0.0424 3.42 0.359 0.0355 3.22 4.692 0.9996 1965121 CMLD1_000084 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D22 mock treatment 0.317 0.00142 0.11 0.322 -0.00153 -0.14 -0.0174 -0.0969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D23 mock treatment 0.32 0.00442 0.36 0.328 0.00447 0.41 0.5385 0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 D24 positive control 0.085 -0.231 -18.57 0.104 -0.22 -19.93 -27.22 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E01 compound treatment 0.323 0.00742 0.6 0.341 0.0175 1.59 1.5438 0.9109 1965122 CMLD1_000085 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E02 compound treatment 0.326 0.0104 0.84 0.343 0.0195 1.77 1.843 0.942 1965123 CMLD1_000086 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E03 compound treatment 0.307 -0.00858 -0.69 0.318 -0.00553 -0.5 -0.8435 -0.9876 1965124 CMLD1_000087 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E04 compound treatment 0.338 0.0224 1.81 0.352 0.0285 2.58 3.1039 0.9846 1965125 CMLD1_000088 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E05 compound treatment 0.3 -0.0156 -1.25 0.309 -0.0145 -1.32 -1.8198 -0.9997 1965126 CMLD1_000089 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E06 compound treatment 0.348 0.0324 2.61 0.346 0.0225 2.04 3.2882 0.9926 1965127 CMLD1_000090 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E07 compound treatment 0.3 -0.0156 -1.25 0.31 -0.0135 -1.23 -1.7556 -0.9999 1965128 CMLD1_000091 CCCCC=C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E08 compound treatment 0.34 0.0244 1.97 0.35 0.0265 2.4 3.0894 0.995 1965129 CMLD1_000092 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E09 compound treatment 0.315 -5.83E-4 -0.05 0.317 -0.00653 -0.59 -0.4522 -0.7608 1965130 CMLD1_000093 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E10 compound treatment 0.346 0.0304 2.45 0.356 0.0325 2.95 3.8162 0.9958 1965131 CMLD1_000094 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E11 compound treatment 0.367 0.0514 4.14 0.373 0.0495 4.49 6.1031 0.9992 1965060 CMLD1_000095 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E12 compound treatment 0.342 0.0264 2.13 0.339 0.0155 1.4 2.4973 0.9797 1965132 CMLD1_000096 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E13 compound treatment 0.335 0.0194 1.56 0.35 0.0265 2.4 2.8047 0.9783 1965133 CMLD1_000097 CCCCC=C[C@@H](NC(=O)OCc1ccccc1Cl)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E14 compound treatment 0.345 0.0294 2.37 0.35 0.0265 2.4 3.3741 1.0 1965134 CMLD1_000098 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E15 compound treatment 0.311 -0.00458 -0.37 0.322 -0.00153 -0.14 -0.359 -0.9106 1965135 CMLD1_000099 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E16 compound treatment 0.345 0.0294 2.37 0.347 0.0235 2.13 3.1816 0.9986 1965136 CMLD1_000100 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E17 compound treatment 0.311 -0.00458 -0.37 0.325 0.00147 0.13 -0.1665 -0.4241 1965137 CMLD1_000101 CC(=CC1CCCCC1)[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E18 compound treatment 0.349 0.0334 2.69 0.349 0.0255 2.31 3.5377 0.9971 1965138 CMLD1_000102 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E19 compound treatment 0.331 0.0154 1.24 0.341 0.0175 1.59 1.9993 0.9927 1965139 CMLD1_000103 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccc(cc3)c4ccccc4)c5ccc(Cl)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E20 compound treatment 0.353 0.0374 3.01 0.358 0.0345 3.13 4.3431 0.9998 1965140 CMLD1_000104 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E21 compound treatment 0.325 0.00942 0.76 0.336 0.0125 1.13 1.3367 0.981 1965141 CMLD1_000105 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccccc2)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E22 mock treatment 0.306 -0.00958 -0.77 0.315 -0.00853 -0.77 -1.093 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E23 mock treatment 0.325 0.00942 0.76 0.317 -0.00653 -0.59 0.1172 0.1218 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 E24 positive control 0.087 -0.229 -18.41 0.099 -0.225 -20.38 -27.4271 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F01 compound treatment 0.351 0.0354 2.85 0.367 0.0435 3.95 4.8069 0.9873 1965142 CMLD1_000106 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CCOCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F02 compound treatment 0.321 0.00542 0.44 0.355 0.0315 2.86 2.3285 0.8057 1965143 CMLD1_000107 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F03 compound treatment 0.328 0.0124 1.0 0.34 0.0165 1.5 1.7643 0.9809 1965144 CMLD1_000108 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F04 compound treatment 0.315 -5.83E-4 -0.05 0.331 0.00747 0.68 0.4464 0.6566 1965145 CMLD1_000109 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5cccc(OC)c5)CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F05 compound treatment 0.347 0.0314 2.53 0.334 0.0105 0.95 2.4611 0.9106 1965146 CMLD1_000110 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F06 compound treatment 0.335 0.0194 1.56 0.338 0.0145 1.31 2.0345 0.9962 1965147 CMLD1_000111 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F07 compound treatment 0.337 0.0214 1.72 0.335 0.0115 1.04 1.9558 0.9708 1965148 CMLD1_000112 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F08 compound treatment 0.312 -0.00358 -0.29 0.336 0.0125 1.13 0.5965 0.5106 1965149 CMLD1_000113 CCCCCC1=C2CNC(C)(C=C2C(C)C1=O)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F09 compound treatment 0.349 0.0334 2.69 0.352 0.0285 2.58 3.7303 0.9998 1965150 CMLD1_000114 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F10 compound treatment 0.339 0.0234 1.89 0.345 0.0215 1.95 2.7116 0.9999 1965151 CMLD1_000115 CCCCCC1=C2CNC(Cc3ccccc3)(C=C2C(C)C1=O)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F11 compound treatment 0.346 0.0304 2.45 0.338 0.0145 1.31 2.6609 0.9574 1965152 CMLD1_000116 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F12 compound treatment 0.355 0.0394 3.17 0.358 0.0345 3.13 4.457 1.0 1965153 CMLD1_000117 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(OC)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F13 compound treatment 0.348 0.0324 2.61 0.356 0.0325 2.95 3.9301 0.9982 1965154 CMLD1_000118 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F14 compound treatment 0.338 0.0224 1.81 0.357 0.0335 3.04 3.4248 0.9691 1965155 CMLD1_000119 C[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F15 compound treatment 0.353 0.0374 3.01 0.36 0.0365 3.31 4.4715 0.9989 1965156 CMLD1_000120 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F16 compound treatment 0.331 0.0154 1.24 0.336 0.0125 1.13 1.6784 0.9989 1965157 CMLD1_000121 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(cc5)C(F)(F)F)C=C21)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F17 compound treatment 0.366 0.0504 4.06 0.362 0.0385 3.49 5.3401 0.9972 1965158 CMLD1_000122 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F18 compound treatment 0.362 0.0464 3.74 0.367 0.0435 3.95 5.4333 0.9996 1965150 CMLD1_000123 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F19 compound treatment 0.358 0.0424 3.42 0.353 0.0295 2.68 4.3069 0.9927 1965159 CMLD1_000124 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F20 compound treatment 0.355 0.0394 3.17 0.359 0.0355 3.22 4.5212 1.0 1965160 CMLD1_000125 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F21 compound treatment 0.356 0.0404 3.25 0.359 0.0355 3.22 4.5781 1.0 1965161 CMLD1_000126 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F22 mock treatment 0.316 4.17E-4 0.03 0.334 0.0105 0.95 0.6959 0.7316 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F23 mock treatment 0.314 -0.00158 -0.13 0.321 -0.00253 -0.23 -0.2524 -0.9615 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 F24 positive control 0.088 -0.228 -18.33 0.096 -0.228 -20.65 -27.5627 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G01 compound treatment 0.314 -0.00158 -0.13 0.323 -5.28E-4 -0.05 -0.124 -0.9106 1965162 CMLD1_000127 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G02 compound treatment 0.344 0.0284 2.29 0.343 0.0195 1.77 2.8679 0.9919 1965163 CMLD1_000128 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G03 compound treatment 0.294 -0.0216 -1.74 0.309 -0.0145 -1.32 -2.1614 -0.9907 1965164 CMLD1_000129 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccccc1)c2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G04 compound treatment 0.348 0.0324 2.61 0.362 0.0385 3.49 4.3152 0.9897 1965165 CMLD1_000130 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G05 compound treatment 0.299 -0.0166 -1.34 0.324 4.72E-4 0.04 -0.914 -0.6841 1965166 CMLD1_000131 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G06 compound treatment 0.325 0.00942 0.76 0.359 0.0355 3.22 2.813 0.8504 1965167 CMLD1_000132 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G07 compound treatment 0.304 -0.0116 -0.93 0.326 0.00247 0.22 -0.5009 -0.5221 1965168 CMLD1_000133 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G08 compound treatment 0.339 0.0234 1.89 0.367 0.0435 3.95 4.1236 0.9429 1965169 CMLD1_000134 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G09 compound treatment 0.334 0.0184 1.48 0.352 0.0285 2.58 2.8762 0.9652 1965170 CMLD1_000135 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G10 compound treatment 0.349 0.0334 2.69 0.364 0.0405 3.67 4.5005 0.9883 1965171 CMLD1_000136 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)c(F)c(F)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G11 compound treatment 0.319 0.00342 0.28 0.321 -0.00253 -0.23 0.0323 0.0902 1965172 CMLD1_000137 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G12 compound treatment 0.351 0.0354 2.85 0.371 0.0475 4.31 5.0637 0.9799 1965173 CMLD1_000138 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G13 compound treatment 0.31 -0.00558 -0.45 0.334 0.0105 0.95 0.3542 0.3369 1965174 CMLD1_000139 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G14 compound treatment 0.347 0.0314 2.53 0.355 0.0315 2.86 3.8089 0.9982 1965175 CMLD1_000140 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G15 compound treatment 0.317 0.00142 0.11 0.347 0.0235 2.13 1.5872 0.7439 1965176 CMLD1_000141 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G16 compound treatment 0.347 0.0314 2.53 0.359 0.0355 3.22 4.0657 0.9929 1965177 CMLD1_000142 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G17 compound treatment 0.326 0.0104 0.84 0.347 0.0235 2.13 2.0997 0.917 1965178 CMLD1_000143 CC(=CC1CCCCC1)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G18 compound treatment 0.351 0.0354 2.85 0.36 0.0365 3.31 4.3576 0.9972 1965179 CMLD1_000144 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G19 compound treatment 0.344 0.0284 2.29 0.36 0.0365 3.31 3.959 0.9837 1965180 CMLD1_000145 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G20 compound treatment 0.352 0.0364 2.93 0.368 0.0445 4.04 4.928 0.9877 1965181 CMLD1_000146 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G21 compound treatment 0.362 0.0464 3.74 0.368 0.0445 4.04 5.4975 0.9993 1965182 CMLD1_000147 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G22 mock treatment 0.315 -5.83E-4 -0.05 0.325 0.00147 0.13 0.0613 0.4326 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G23 mock treatment 0.315 -5.83E-4 -0.05 0.323 -5.28E-4 -0.05 -0.0671 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 G24 positive control 0.088 -0.228 -18.33 0.095 -0.229 -20.74 -27.6269 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H01 compound treatment 0.353 0.0374 3.01 0.355 0.0315 2.86 4.1506 0.9996 1965183 CMLD1_000148 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H02 compound treatment 0.334 0.0184 1.48 0.365 0.0415 3.76 3.7106 0.9171 1965184 CMLD1_000149 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H03 compound treatment 0.323 0.00742 0.6 0.357 0.0335 3.04 2.5707 0.8302 1965185 CMLD1_000150 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H04 compound treatment 0.31 -0.00558 -0.45 0.355 0.0315 2.86 1.7021 0.5886 1965186 CMLD1_000151 CCCC[C@H]1C[C@@H]1[C@@H]2N(C[C@](O)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H05 compound treatment 0.319 0.00342 0.28 0.339 0.0155 1.4 1.1876 0.8299 1965187 CMLD1_000152 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H06 compound treatment 0.319 0.00342 0.28 0.361 0.0375 3.4 2.5997 0.7618 1965147 CMLD1_000153 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H07 compound treatment 0.333 0.0174 1.4 0.375 0.0515 4.67 4.2955 0.8805 1965188 CMLD1_000154 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H08 compound treatment 0.325 0.00942 0.76 0.378 0.0545 4.94 4.0325 0.8061 1965189 CMLD1_000155 CCCC1(NCC2=C(C)C(=O)C(C)C2=C1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H09 compound treatment 0.344 0.0284 2.29 0.385 0.0615 5.58 5.5637 0.9225 1965190 CMLD1_000156 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H10 compound treatment 0.327 0.0114 0.92 0.382 0.0585 5.31 4.4031 0.8174 1965191 CMLD1_000157 COC(=O)C1(CC(C)C)NCC2=C(C)C(=O)C(C)C2=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H11 compound treatment 0.338 0.0224 1.81 0.373 0.0495 4.49 4.4518 0.9198 1965192 CMLD1_000158 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H12 compound treatment 0.344 0.0284 2.29 0.365 0.0415 3.76 4.28 0.9715 1965193 CMLD1_000159 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H13 compound treatment 0.352 0.0364 2.93 0.374 0.0505 4.58 5.3132 0.9768 1965194 CMLD1_000160 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H14 compound treatment 0.335 0.0194 1.56 0.383 0.0595 5.4 4.9228 0.8759 1965195 CMLD1_000161 C[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H15 compound treatment 0.35 0.0344 2.77 0.395 0.0715 6.49 6.5472 0.928 1965196 CMLD1_000162 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H16 compound treatment 0.329 0.0134 1.08 0.374 0.0505 4.58 4.0035 0.8505 1965197 CMLD1_000163 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(cc6)C(F)(F)F)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H17 compound treatment 0.361 0.0454 3.66 0.361 0.0375 3.4 4.9912 0.9993 1965198 CMLD1_000164 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H18 compound treatment 0.364 0.0484 3.9 0.382 0.0585 5.31 6.5099 0.9885 1965199 CMLD1_000165 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H19 compound treatment 0.353 0.0374 3.01 0.364 0.0405 3.67 4.7282 0.9952 1965200 CMLD1_000166 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H20 compound treatment 0.362 0.0464 3.74 0.36 0.0365 3.31 4.984 0.9982 1965201 CMLD1_000167 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H21 compound treatment 0.312 -0.00358 -0.29 0.328 0.00447 0.41 0.083 0.1667 1965202 CMLD1_000168 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H22 mock treatment 0.314 -0.00158 -0.13 0.33 0.00647 0.59 0.3253 0.5411 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H23 mock treatment 0.316 4.17E-4 0.03 0.325 0.00147 0.13 0.1182 0.858 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 H24 positive control 0.09 -0.226 -18.17 0.098 -0.226 -20.47 -27.3204 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I01 compound treatment 0.321 0.00542 0.44 0.33 0.00647 0.59 0.7238 0.9893 1965203 CMLD1_000169 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I02 compound treatment 0.351 0.0354 2.85 0.372 0.0485 4.4 5.1278 0.978 1965204 CMLD1_000170 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I03 compound treatment 0.297 -0.0186 -1.5 0.325 0.00147 0.13 -0.9637 -0.6414 1965205 CMLD1_000171 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I04 compound treatment 0.321 0.00542 0.44 0.337 0.0135 1.22 1.1731 0.9036 1965206 CMLD1_000172 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I05 compound treatment 0.339 0.0234 1.89 0.357 0.0335 3.04 3.4818 0.9737 1965207 CMLD1_000173 CCCC=C(CCC)[C@@H](NC(=O)c1ccco1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I06 compound treatment 0.336 0.0204 1.64 0.339 0.0155 1.4 2.1556 0.9969 1965208 CMLD1_000174 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I07 compound treatment 0.32 0.00442 0.36 0.317 -0.00653 -0.59 -0.1675 -0.2424 1965209 CMLD1_000175 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I08 compound treatment 0.356 0.0404 3.25 0.348 0.0245 2.22 3.8721 0.9827 1965210 CMLD1_000176 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I09 compound treatment 0.301 -0.0146 -1.17 0.316 -0.00753 -0.68 -1.3136 -0.9668 1965211 CMLD1_000177 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I10 compound treatment 0.335 0.0194 1.56 0.365 0.0415 3.76 3.7675 0.9242 1965212 CMLD1_000178 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I11 compound treatment 0.321 0.00542 0.44 0.351 0.0275 2.49 2.0717 0.8184 1965213 CMLD1_000179 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I12 compound treatment 0.337 0.0214 1.72 0.362 0.0385 3.49 3.6888 0.9471 1965214 CMLD1_000180 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I13 compound treatment 0.317 0.00142 0.11 0.336 0.0125 1.13 0.8812 0.7744 1965215 CMLD1_000181 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I14 compound treatment 0.349 0.0334 2.69 0.369 0.0455 4.13 4.8214 0.9785 1965216 CMLD1_000182 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I15 compound treatment 0.322 0.00642 0.52 0.335 0.0115 1.04 1.1017 0.9477 1965217 CMLD1_000183 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I16 compound treatment 0.363 0.0474 3.82 0.371 0.0475 4.31 5.747 0.9982 1965218 CMLD1_000184 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I17 compound treatment 0.337 0.0214 1.72 0.344 0.0205 1.86 2.5335 0.9993 1965219 CMLD1_000185 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccccc2)[C@]3(C)C[C@H]3C4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I18 compound treatment 0.312 -0.00358 -0.29 0.327 0.00347 0.32 0.0188 0.0441 1965220 CMLD1_000186 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I19 compound treatment 0.355 0.0394 3.17 0.368 0.0445 4.04 5.0989 0.9929 1965221 CMLD1_000187 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccccc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I20 compound treatment 0.359 0.0434 3.5 0.356 0.0325 2.95 4.5564 0.9964 1965222 CMLD1_000188 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I21 compound treatment 0.365 0.0494 3.98 0.361 0.0375 3.4 5.219 0.9969 1965223 CMLD1_000189 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CC6CC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I22 mock treatment 0.32 0.00442 0.36 0.327 0.00347 0.32 0.4744 0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I23 mock treatment 0.316 4.17E-4 0.03 0.325 0.00147 0.13 0.1182 0.858 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 I24 positive control 0.09 -0.226 -18.17 0.095 -0.229 -20.74 -27.513 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J01 compound treatment 0.352 0.0364 2.93 0.366 0.0425 3.86 4.7997 0.9909 1965224 CMLD1_000190 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J02 compound treatment 0.342 0.0264 2.13 0.363 0.0395 3.58 4.0377 0.969 1965225 CMLD1_000191 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J03 compound treatment 0.324 0.00842 0.68 0.345 0.0215 1.95 1.8574 0.9001 1965226 CMLD1_000192 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J04 compound treatment 0.317 0.00142 0.11 0.34 0.0165 1.5 1.1379 0.7589 1965227 CMLD1_000193 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@](CO)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J05 compound treatment 0.334 0.0184 1.48 0.344 0.0205 1.86 2.3627 0.9938 1965228 CMLD1_000194 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J06 compound treatment 0.338 0.0224 1.81 0.347 0.0235 2.13 2.783 0.9966 1965229 CMLD1_000195 OC1(CN(CC2(CC2)C1)P(=O)(c3ccccc3)c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J07 compound treatment 0.343 0.0274 2.21 0.352 0.0285 2.58 3.3886 0.9969 1965230 CMLD1_000196 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J08 compound treatment 0.329 0.0134 1.08 0.321 -0.00253 -0.23 0.6017 0.5448 1965231 CMLD1_000197 CCCC1(NCC2=C(C(C)C)C(=O)C(C)C2=C1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J09 compound treatment 0.343 0.0274 2.21 0.355 0.0315 2.86 3.5812 0.9919 1965232 CMLD1_000198 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J10 compound treatment 0.321 0.00542 0.44 0.333 0.00947 0.86 0.9164 0.9505 1965233 CMLD1_000199 COC(=O)C1(CC(C)C)NCC2=C(C(C)C)C(=O)C(C)C2=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J11 compound treatment 0.346 0.0304 2.45 0.351 0.0275 2.49 3.4953 1.0 1965234 CMLD1_000200 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J12 compound treatment 0.348 0.0324 2.61 0.352 0.0285 2.58 3.6733 1.0 1965235 CMLD1_000201 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cccc(Cl)c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J13 compound treatment 0.351 0.0354 2.85 0.353 0.0295 2.68 3.9083 0.9995 1965236 CMLD1_000202 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J14 compound treatment 0.357 0.0414 3.34 0.361 0.0375 3.4 4.7635 1.0 1965237 CMLD1_000203 CC[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J15 compound treatment 0.36 0.0444 3.58 0.363 0.0395 3.58 5.0626 1.0 1965238 CMLD1_000204 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J16 compound treatment 0.347 0.0314 2.53 0.341 0.0175 1.59 2.9103 0.9747 1965239 CMLD1_000205 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J17 compound treatment 0.353 0.0374 3.01 0.354 0.0305 2.77 4.0864 0.9991 1965240 CMLD1_000206 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J18 compound treatment 0.349 0.0334 2.69 0.361 0.0375 3.4 4.3079 0.9933 1965241 CMLD1_000207 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J19 compound treatment 0.365 0.0494 3.98 0.354 0.0305 2.77 4.7697 0.9842 1965242 CMLD1_000208 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J20 compound treatment 0.36 0.0444 3.58 0.355 0.0315 2.86 4.5492 0.9938 1965243 CMLD1_000209 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J21 compound treatment 0.32 0.00442 0.36 0.329 0.00547 0.5 0.6027 0.9866 1965244 CMLD1_000210 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J22 mock treatment 0.318 0.00242 0.19 0.326 0.00247 0.22 0.2963 0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J23 mock treatment 0.315 -5.83E-4 -0.05 0.319 -0.00453 -0.41 -0.3238 -0.7828 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 J24 positive control 0.09 -0.226 -18.17 0.096 -0.228 -20.65 -27.4488 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K01 compound treatment 0.319 0.00342 0.28 0.333 0.00947 0.86 0.8025 0.889 1965245 CMLD1_000211 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K02 compound treatment 0.332 0.0164 1.32 0.351 0.0275 2.49 2.6981 0.9559 1965246 CMLD1_000212 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K03 compound treatment 0.306 -0.00958 -0.77 0.328 0.00447 0.41 -0.2586 -0.2966 1965247 CMLD1_000213 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K04 compound treatment 0.349 0.0334 2.69 0.359 0.0355 3.22 4.1796 0.996 1965248 CMLD1_000214 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K05 compound treatment 0.346 0.0304 2.45 0.35 0.0265 2.4 3.4311 1.0 1965249 CMLD1_000215 CCCC=C(CCC)[C@@H](NC(=O)C(C)(C)C)c1ccc(cc1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K06 compound treatment 0.354 0.0384 3.09 0.357 0.0335 3.04 4.3359 1.0 1965250 CMLD1_000216 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K07 compound treatment 0.338 0.0224 1.81 0.359 0.0355 3.22 3.5532 0.9626 1965251 CMLD1_000217 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K08 compound treatment 0.328 0.0124 1.0 0.34 0.0165 1.5 1.7643 0.9809 1965252 CMLD1_000218 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K09 compound treatment 0.332 0.0164 1.32 0.352 0.0285 2.58 2.7623 0.9515 1965253 CMLD1_000219 CCCC=C(CCC)[C@@H](NC(=O)Cc1ccccc1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K10 compound treatment 0.354 0.0384 3.09 0.371 0.0475 4.31 5.2345 0.9868 1965254 CMLD1_000220 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K11 compound treatment 0.292 -0.0236 -1.9 0.31 -0.0135 -1.23 -2.2111 -0.9777 1965255 CMLD1_000221 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K12 compound treatment 0.352 0.0364 2.93 0.365 0.0415 3.76 4.7355 0.9924 1965256 CMLD1_000222 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K13 compound treatment 0.295 -0.0206 -1.66 0.305 -0.0185 -1.68 -2.3612 -1.0 1965257 CMLD1_000223 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K14 compound treatment 0.337 0.0214 1.72 0.36 0.0365 3.31 3.5605 0.9538 1965258 CMLD1_000224 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K15 compound treatment 0.306 -0.00958 -0.77 0.315 -0.00853 -0.77 -1.093 -1.0 1965259 CMLD1_000225 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K16 compound treatment 0.358 0.0424 3.42 0.354 0.0305 2.77 4.3711 0.9945 1965260 CMLD1_000226 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K17 compound treatment 0.359 0.0434 3.5 0.364 0.0405 3.67 5.0699 0.9997 1965261 CMLD1_000227 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccco2)[C@]3(C)C[C@H]3C4CCCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K18 compound treatment 0.354 0.0384 3.09 0.351 0.0275 2.49 3.9508 0.9943 1965262 CMLD1_000228 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K19 compound treatment 0.347 0.0314 2.53 0.349 0.0255 2.31 3.4238 0.999 1965263 CMLD1_000229 CCCC[C@@H]1C[C@H]1[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K20 compound treatment 0.352 0.0364 2.93 0.353 0.0295 2.68 3.9653 0.9989 1965264 CMLD1_000230 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K21 compound treatment 0.352 0.0364 2.93 0.341 0.0175 1.59 3.1951 0.9584 1965265 CMLD1_000231 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K22 mock treatment 0.317 0.00142 0.11 0.328 0.00447 0.41 0.3677 0.872 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K23 mock treatment 0.314 -0.00158 -0.13 0.32 -0.00353 -0.32 -0.3166 -0.9185 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 K24 positive control 0.092 -0.224 -18.0 0.097 -0.227 -20.56 -27.2707 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L01 compound treatment 0.354 0.0384 3.09 0.357 0.0335 3.04 4.3359 1.0 1965266 CMLD1_000232 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L02 compound treatment 0.362 0.0464 3.74 0.37 0.0465 4.22 5.6258 0.9982 1965267 CMLD1_000233 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L03 compound treatment 0.334 0.0184 1.48 0.361 0.0375 3.4 3.4538 0.9308 1965268 CMLD1_000234 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L04 compound treatment 0.327 0.0114 0.92 0.336 0.0125 1.13 1.4506 0.9947 1965269 CMLD1_000235 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@H](CC32CC3)c4cccc(OC)c4)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L05 compound treatment 0.355 0.0394 3.17 0.355 0.0315 2.86 4.2645 0.9986 1965270 CMLD1_000236 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7cc8ccccc8[nH]7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L06 compound treatment 0.345 0.0294 2.37 0.356 0.0325 2.95 3.7592 0.9941 1965271 CMLD1_000237 C=C(CC1(CNP(=O)(c2ccccc2)c3ccccc3)CC1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L07 compound treatment 0.347 0.0314 2.53 0.36 0.0365 3.31 4.1299 0.9912 1965272 CMLD1_000238 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L08 compound treatment 0.338 0.0224 1.81 0.339 0.0155 1.4 2.2695 0.9923 1965273 CMLD1_000239 CCCC1(NCC2=C(C(=O)C(C)C2=C1)c3ccccc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L09 compound treatment 0.355 0.0394 3.17 0.354 0.0305 2.77 4.2003 0.9976 1965274 CMLD1_000240 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L10 compound treatment 0.338 0.0224 1.81 0.338 0.0145 1.31 2.2053 0.9878 1965275 CMLD1_000241 COC(=O)C1(CC(C)C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L11 compound treatment 0.359 0.0434 3.5 0.36 0.0365 3.31 4.8132 0.9996 1965276 CMLD1_000242 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L12 compound treatment 0.356 0.0404 3.25 0.348 0.0245 2.22 3.8721 0.9827 1965277 CMLD1_000243 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cc(F)cc(F)c5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L13 compound treatment 0.357 0.0414 3.34 0.354 0.0305 2.77 4.3142 0.9957 1965278 CMLD1_000244 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L14 compound treatment 0.336 0.0204 1.64 0.356 0.0325 2.95 3.2468 0.962 1965279 CMLD1_000245 CC[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L15 compound treatment 0.358 0.0424 3.42 0.358 0.0345 3.13 4.6278 0.999 1965280 CMLD1_000246 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L16 compound treatment 0.333 0.0174 1.4 0.345 0.0215 1.95 2.3699 0.987 1965281 CMLD1_000247 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccccc6)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L17 compound treatment 0.354 0.0384 3.09 0.355 0.0315 2.86 4.2075 0.9992 1965282 CMLD1_000248 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSC(=N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L18 compound treatment 0.348 0.0324 2.61 0.356 0.0325 2.95 3.9301 0.9982 1965079 CMLD1_000249 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L19 compound treatment 0.357 0.0414 3.34 0.372 0.0485 4.4 5.4695 0.9907 1965283 CMLD1_000250 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L20 compound treatment 0.351 0.0354 2.85 0.36 0.0365 3.31 4.3576 0.9972 1965284 CMLD1_000251 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L21 compound treatment 0.358 0.0424 3.42 0.358 0.0345 3.13 4.6278 0.999 1965285 CMLD1_000252 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L22 mock treatment 0.316 4.17E-4 0.03 0.325 0.00147 0.13 0.1182 0.858 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L23 mock treatment 0.317 0.00142 0.11 0.325 0.00147 0.13 0.1752 0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 L24 positive control 0.094 -0.222 -17.84 0.097 -0.227 -20.56 -27.1568 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M01 compound treatment 0.316 4.17E-4 0.03 0.342 0.0185 1.68 1.2094 0.7211 1965286 CMLD1_000253 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M02 compound treatment 0.324 0.00842 0.68 0.338 0.0145 1.31 1.4082 0.9526 1965287 CMLD1_000254 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M03 compound treatment 0.302 -0.0136 -1.09 0.317 -0.00653 -0.59 -1.1924 -0.9585 1965288 CMLD1_000255 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M04 compound treatment 0.34 0.0244 1.97 0.359 0.0355 3.22 3.6671 0.972 1965289 CMLD1_000256 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(C)onc7c8ccccc8 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M05 compound treatment 0.332 0.0164 1.32 0.331 0.00747 0.68 1.4144 0.9519 1965290 CMLD1_000257 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M06 compound treatment 0.331 0.0154 1.24 0.346 0.0225 2.04 2.3202 0.9717 1965090 CMLD1_000258 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M07 compound treatment 0.336 0.0204 1.64 0.345 0.0215 1.95 2.5407 0.9964 1965291 CMLD1_000259 CCCCC=C[C@@H](NC(=O)c1ccco1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M08 compound treatment 0.325 0.00942 0.76 0.366 0.0425 3.86 3.2623 0.8303 1965292 CMLD1_000260 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M09 compound treatment 0.294 -0.0216 -1.74 0.32 -0.00353 -0.32 -1.4554 -0.8235 1965293 CMLD1_000261 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)OCc2ccccc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M10 compound treatment 0.332 0.0164 1.32 0.366 0.0425 3.86 3.6609 0.8982 1965294 CMLD1_000262 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCCNc6ccc(cc6Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M11 compound treatment 0.315 -5.83E-4 -0.05 0.328 0.00447 0.41 0.2538 0.6211 1965295 CMLD1_000263 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M12 compound treatment 0.334 0.0184 1.48 0.362 0.0385 3.49 3.518 0.9272 1965296 CMLD1_000264 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M13 compound treatment 0.32 0.00442 0.36 0.331 0.00747 0.68 0.7311 0.9546 1965297 CMLD1_000265 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M14 compound treatment 0.348 0.0324 2.61 0.353 0.0295 2.68 3.7375 0.9999 1965298 CMLD1_000266 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M15 compound treatment 0.325 0.00942 0.76 0.332 0.00847 0.77 1.08 1.0 1965299 CMLD1_000267 CCCC[C@@H]1C[C@H]1[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M16 compound treatment 0.335 0.0194 1.56 0.343 0.0195 1.77 2.3554 0.9981 1965300 CMLD1_000268 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(O)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M17 compound treatment 0.341 0.0254 2.05 0.345 0.0215 1.95 2.8254 0.9997 1965301 CMLD1_000269 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M18 compound treatment 0.354 0.0384 3.09 0.352 0.0285 2.58 4.015 0.996 1965302 CMLD1_000270 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M19 compound treatment 0.344 0.0284 2.29 0.345 0.0215 1.95 2.9963 0.9968 1965303 CMLD1_000271 CCCC=C(CCC)[C@@H](NC(=O)Oc1ccc(F)cc1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M20 compound treatment 0.347 0.0314 2.53 0.34 0.0165 1.5 2.8462 0.9685 1965304 CMLD1_000272 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M21 mock treatment 0.308 -0.00758 -0.61 0.318 -0.00553 -0.5 -0.7866 -0.9952 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M22 mock treatment 0.316 4.17E-4 0.03 0.324 4.72E-4 0.04 0.054 0.9927 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M23 mock treatment 0.312 -0.00358 -0.29 0.317 -0.00653 -0.59 -0.623 -0.9453 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 M24 positive control 0.092 -0.224 -18.0 0.099 -0.225 -20.38 -27.1424 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N01 compound treatment 0.353 0.0374 3.01 0.36 0.0365 3.31 4.4715 0.9989 1965305 CMLD1_000273 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N02 compound treatment 0.341 0.0254 2.05 0.354 0.0305 2.77 3.4031 0.989 1965306 CMLD1_000274 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N03 compound treatment 0.345 0.0294 2.37 0.356 0.0325 2.95 3.7592 0.9941 1965307 CMLD1_000275 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N04 compound treatment 0.33 0.0144 1.16 0.337 0.0135 1.22 1.6856 0.9997 1965308 CMLD1_000276 COC(=O)c1ccc(C#CC(NP(=O)(c2ccccc2)c3ccccc3)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N05 compound treatment 0.34 0.0244 1.97 0.353 0.0295 2.68 3.282 0.9885 1965309 CMLD1_000277 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N06 compound treatment 0.323 0.00742 0.6 0.342 0.0185 1.68 1.608 0.9034 1965310 CMLD1_000278 O=P(NCC1(CC2(CO2)c3ccccc3)CC1)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N07 compound treatment 0.356 0.0404 3.25 0.357 0.0335 3.04 4.4498 0.9994 1965311 CMLD1_000279 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N08 compound treatment 0.342 0.0264 2.13 0.349 0.0255 2.31 3.1391 0.9991 1965312 CMLD1_000280 CCCCCC1=C2CNC(CCC)(C=C2C(C)C1=O)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N09 compound treatment 0.356 0.0404 3.25 0.355 0.0315 2.86 4.3214 0.9979 1965313 CMLD1_000281 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CCOCC7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N10 compound treatment 0.336 0.0204 1.64 0.354 0.0305 2.77 3.1184 0.9691 1965314 CMLD1_000282 CCCCCC1=C2CNC(CC(C)C)(C=C2C(C)C1=O)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N11 compound treatment 0.354 0.0384 3.09 0.362 0.0385 3.49 4.6568 0.9982 1965315 CMLD1_000283 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N12 compound treatment 0.34 0.0244 1.97 0.357 0.0335 3.04 3.5387 0.9778 1965316 CMLD1_000284 COC1OC[C@]2(C)[C@@H]3[C@H]1CCC4C(CO)C(CO)[C@@H](C)C(=C43)CN2C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N13 compound treatment 0.348 0.0324 2.61 0.354 0.0305 2.77 3.8017 0.9996 1965317 CMLD1_000285 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N14 compound treatment 0.345 0.0294 2.37 0.359 0.0355 3.22 3.9518 0.9886 1965318 CMLD1_000286 CC[C@@H]1C(COC)C(COC)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N15 compound treatment 0.348 0.0324 2.61 0.355 0.0315 2.86 3.8659 0.999 1965319 CMLD1_000287 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N16 compound treatment 0.381 0.0654 5.27 0.368 0.0445 4.04 6.5793 0.9914 1965320 CMLD1_000288 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccccc5)C=C21)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N17 compound treatment 0.343 0.0274 2.21 0.348 0.0245 2.22 3.1319 1.0 1965321 CMLD1_000289 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N18 compound treatment 0.35 0.0344 2.77 0.356 0.0325 2.95 4.0439 0.9995 1965322 CMLD1_000290 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N19 compound treatment 0.34 0.0244 1.97 0.355 0.0315 2.86 3.4104 0.9834 1965323 CMLD1_000291 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(O)cc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N20 compound treatment 0.357 0.0414 3.34 0.355 0.0315 2.86 4.3783 0.997 1965324 CMLD1_000292 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N21 mock treatment 0.317 0.00142 0.11 0.327 0.00347 0.32 0.3035 0.9056 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N22 mock treatment 0.317 0.00142 0.11 0.325 0.00147 0.13 0.1752 0.9969 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N23 mock treatment 0.316 4.17E-4 0.03 0.322 -0.00153 -0.14 -0.0743 -0.521 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 N24 positive control 0.092 -0.224 -18.0 0.1 -0.224 -20.29 -27.0782 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O01 compound treatment 0.328 0.0124 1.0 0.344 0.0205 1.86 2.021 0.9577 1965325 CMLD1_000293 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccc(cc1)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O02 compound treatment 0.322 0.00642 0.52 0.336 0.0125 1.13 1.1659 0.9369 1965326 CMLD1_000294 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O03 compound treatment 0.3 -0.0156 -1.25 0.321 -0.00253 -0.23 -1.0496 -0.8228 1965327 CMLD1_000295 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O04 compound treatment 0.349 0.0334 2.69 0.365 0.0415 3.76 4.5647 0.9865 1965268 CMLD1_000296 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O05 compound treatment 0.336 0.0204 1.64 0.347 0.0235 2.13 2.6691 0.9918 1965328 CMLD1_000297 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O06 compound treatment 0.334 0.0184 1.48 0.353 0.0295 2.68 2.9403 0.9613 1965329 CMLD1_000298 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O07 compound treatment 0.297 -0.0186 -1.5 0.31 -0.0135 -1.23 -1.9264 -0.9952 1965330 CMLD1_000299 CCCCC=C[C@@H](NC(=O)c1cccs1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O08 compound treatment 0.348 0.0324 2.61 0.357 0.0335 3.04 3.9942 0.9971 1965331 CMLD1_000300 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O09 compound treatment 0.321 0.00542 0.44 0.332 0.00847 0.77 0.8522 0.9639 1965332 CMLD1_000301 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O10 compound treatment 0.33 0.0144 1.16 0.352 0.0285 2.58 2.6484 0.9348 1965333 CMLD1_000302 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O11 compound treatment 0.344 0.0284 2.29 0.362 0.0385 3.49 4.0874 0.979 1965334 CMLD1_000303 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O12 compound treatment 0.367 0.0514 4.14 0.373 0.0495 4.49 6.1031 0.9992 1965335 CMLD1_000304 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O13 compound treatment 0.315 -5.83E-4 -0.05 0.329 0.00547 0.5 0.318 0.6374 1965336 CMLD1_000305 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(cc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O14 compound treatment 0.363 0.0474 3.82 0.363 0.0395 3.58 5.2335 0.9995 1965337 CMLD1_000306 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O15 compound treatment 0.333 0.0174 1.4 0.34 0.0165 1.5 2.049 0.9995 1965338 CMLD1_000307 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O16 compound treatment 0.354 0.0384 3.09 0.363 0.0395 3.58 4.721 0.9973 1965339 CMLD1_000308 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O17 compound treatment 0.324 0.00842 0.68 0.34 0.0165 1.5 1.5365 0.936 1965340 CMLD1_000309 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O18 compound treatment 0.357 0.0414 3.34 0.366 0.0425 3.86 5.0844 0.9974 1965341 CMLD1_000310 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O19 compound treatment 0.31 -0.00558 -0.45 0.32 -0.00353 -0.32 -0.5444 -0.9862 1965342 CMLD1_000311 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O20 compound treatment 0.365 0.0494 3.98 0.363 0.0395 3.58 5.3474 0.9986 1965343 CMLD1_000312 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O21 mock treatment 0.329 0.0134 1.08 0.34 0.0165 1.5 1.8212 0.9873 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O22 mock treatment 0.324 0.00842 0.68 0.329 0.00547 0.5 0.8305 0.9883 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O23 mock treatment 0.321 0.00542 0.44 0.326 0.00247 0.22 0.4671 0.9523 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 O24 positive control 0.094 -0.222 -17.84 0.1 -0.224 -20.29 -26.9643 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P01 compound treatment 0.36 0.0444 3.58 0.355 0.0315 2.86 4.5492 0.9938 1965344 CMLD1_000313 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P02 compound treatment 0.354 0.0384 3.09 0.351 0.0275 2.49 3.9508 0.9943 1965345 CMLD1_000314 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P03 compound treatment 0.356 0.0404 3.25 0.362 0.0385 3.49 4.7707 0.9994 1965346 CMLD1_000315 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P04 compound treatment 0.342 0.0264 2.13 0.35 0.0265 2.4 3.2033 0.9982 1965347 CMLD1_000316 COC(=O)c1ccc(cc1)C23CC3(C2)C(NP(=O)(c4ccccc4)c5ccccc5)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P05 compound treatment 0.345 0.0294 2.37 0.35 0.0265 2.4 3.3741 1.0 1965348 CMLD1_000317 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P06 compound treatment 0.353 0.0374 3.01 0.36 0.0365 3.31 4.4715 0.9989 1965349 CMLD1_000318 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P07 compound treatment 0.354 0.0384 3.09 0.359 0.0355 3.22 4.4643 0.9998 1965350 CMLD1_000319 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P08 compound treatment 0.34 0.0244 1.97 0.35 0.0265 2.4 3.0894 0.995 1965351 CMLD1_000320 COC(=O)C1(Cc2ccccc2)NCC3=C(C)C(=O)C(C)C3=C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P09 compound treatment 0.346 0.0304 2.45 0.344 0.0205 1.86 3.046 0.9907 1965352 CMLD1_000321 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P10 compound treatment 0.347 0.0314 2.53 0.35 0.0265 2.4 3.488 0.9997 1965353 CMLD1_000322 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(C)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P11 compound treatment 0.352 0.0364 2.93 0.349 0.0255 2.31 3.7085 0.9931 1965354 CMLD1_000323 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P12 compound treatment 0.349 0.0334 2.69 0.353 0.0295 2.68 3.7944 1.0 1965355 CMLD1_000324 CC[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OC)OC[C@]4(C)[C@H]3C2=C1CN4C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P13 compound treatment 0.353 0.0374 3.01 0.358 0.0345 3.13 4.3431 0.9998 1965356 CMLD1_000325 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P14 compound treatment 0.362 0.0464 3.74 0.362 0.0385 3.49 5.1123 0.9994 1965357 CMLD1_000326 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(OC)cc5)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P15 compound treatment 0.356 0.0404 3.25 0.361 0.0375 3.4 4.7065 0.9998 1965358 CMLD1_000327 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P16 compound treatment 0.364 0.0484 3.9 0.362 0.0385 3.49 5.2262 0.9985 1965359 CMLD1_000328 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)cc7COCOc67 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P17 compound treatment 0.335 0.0194 1.56 0.343 0.0195 1.77 2.3554 0.9981 1965360 CMLD1_000329 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P18 compound treatment 0.359 0.0434 3.5 0.362 0.0385 3.49 4.9415 1.0 1965361 CMLD1_000330 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P19 compound treatment 0.341 0.0254 2.05 0.333 0.00947 0.86 2.0552 0.9258 1965362 CMLD1_000331 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P20 compound treatment 0.358 0.0424 3.42 0.358 0.0345 3.13 4.6278 0.999 1965363 CMLD1_000332 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P21 mock treatment 0.325 0.00942 0.76 0.331 0.00747 0.68 1.0158 0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P22 mock treatment 0.319 0.00342 0.28 0.327 0.00347 0.32 0.4174 0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P23 mock treatment 0.322 0.00642 0.52 0.329 0.00547 0.5 0.7166 0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.1462 P24 positive control 0.097 -0.219 -17.6 0.101 -0.223 -20.2 -26.7293 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A01 mock treatment 0.31 -0.0271 -2.18 0.311 -0.0176 -1.6 -2.6705 -0.9883 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A02 mock treatment 0.312 -0.0251 -2.02 0.319 -0.00959 -0.87 -2.0431 -0.9294 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A03 compound treatment 0.323 -0.0141 -1.13 0.317 -0.0116 -1.05 -1.5451 -0.9993 1248 NINDS_000641 C[C@@]12CCC3C(CCc4cc(OC(=O)CCC(=O)O)ccc34)C2CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A04 compound treatment 0.323 -0.0141 -1.13 0.318 -0.0106 -0.96 -1.4809 -0.9967 1249 NINDS_000642 C[N+](C)(C)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A05 compound treatment 0.318 -0.0191 -1.54 0.315 -0.0136 -1.23 -1.9582 -0.9941 1250 NINDS_000643 COc1cc(C)c2c(=O)cc(oc2c1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A06 compound treatment 0.354 0.0169 1.36 0.347 0.0184 1.67 2.1456 0.9949 1251 NINDS_000644 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A07 compound treatment 0.318 -0.0191 -1.54 0.317 -0.0116 -1.05 -1.8298 -0.983 1252 NINDS_000645 CC(C)NCC(O)c1cc(O)cc(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A08 compound treatment 0.338 9.33E-4 0.08 0.33 0.00141 0.13 0.1434 0.9681 1253 NINDS_000646 C[C@H]1OC=C2C(=C(C(=O)O)C(=O)C(=C2[C@@H]1C)C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A09 compound treatment 0.312 -0.0251 -2.02 0.304 -0.0246 -2.23 -3.0059 -0.9987 1254 NINDS_000647 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A10 compound treatment 0.315 -0.0221 -1.78 0.312 -0.0166 -1.51 -2.3216 -0.9966 1255 NINDS_000648 NC(=O)c1ccc(cc1Cl)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A11 compound treatment 0.325 -0.0121 -0.97 0.311 -0.0176 -1.6 -1.8163 -0.9716 1256 NINDS_000649 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A12 compound treatment 0.292 -0.0451 -3.63 0.292 -0.0366 -3.32 -4.9149 -0.999 1257 NINDS_000650 CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A13 compound treatment 0.325 -0.0121 -0.97 0.314 -0.0146 -1.32 -1.6238 -0.9884 1258 NINDS_000651 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCNCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A14 compound treatment 0.308 -0.0291 -2.34 0.293 -0.0356 -3.23 -3.9397 -0.9875 1259 NINDS_000652 CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A15 compound treatment 0.329 -0.00807 -0.65 0.323 -0.00559 -0.51 -0.8184 -0.9926 1260 NINDS_000653 N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A16 compound treatment 0.309 -0.0281 -2.26 0.309 -0.0196 -1.78 -2.8558 -0.993 1261 NINDS_000654 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A17 compound treatment 0.327 -0.0101 -0.81 0.315 -0.0136 -1.23 -1.4457 -0.9792 1262 NINDS_000655 NC[C@H]1CC[C@@H](CC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A18 compound treatment 0.32 -0.0171 -1.37 0.312 -0.0166 -1.51 -2.0369 -0.999 1263 NINDS_000656 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A19 compound treatment 0.323 -0.0141 -1.13 0.315 -0.0136 -1.23 -1.6735 -0.9991 1264 NINDS_000657 OCc1ccccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A20 compound treatment 0.332 -0.00507 -0.41 0.346 0.0174 1.58 0.8287 0.5079 1265 NINDS_000658 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(Cl)cccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A21 compound treatment 0.321 -0.0161 -1.29 0.312 -0.0166 -1.51 -1.9799 -0.9971 1266 NINDS_000659 CCn1cc(C(=O)O)c(=O)c2cc3OCOc3cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A22 compound treatment 0.324 -0.0131 -1.05 0.312 -0.0166 -1.51 -1.8091 -0.9846 1267 NINDS_000660 CC(=O)Nc1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A23 positive control 0.083 -0.254 -20.46 0.081 -0.248 -22.47 -30.3586 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 A24 positive control 0.084 -0.253 -20.38 0.083 -0.246 -22.29 -30.1733 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B01 mock treatment 0.337 -6.67E-5 -0.01 0.328 -5.94E-4 -0.05 -0.0419 -0.7737 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B02 mock treatment 0.342 0.00493 0.4 0.329 4.06E-4 0.04 0.307 0.7694 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B03 compound treatment 0.354 0.0169 1.36 0.347 0.0184 1.67 2.1456 0.9949 1268 NINDS_000661 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3cc(C)on3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B04 compound treatment 0.357 0.0199 1.61 0.349 0.0204 1.85 2.4448 0.9975 1269 NINDS_000662 CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B05 compound treatment 0.349 0.0119 0.96 0.344 0.0154 1.4 1.6683 0.9832 1270 NINDS_000663 C[N+](C)(C)CCCCCC[N+](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B06 compound treatment 0.35 0.0129 1.04 0.341 0.0124 1.13 1.5327 0.9992 1271 NINDS_000664 CC(=O)OC(CC(=O)O)[N+](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B07 compound treatment 0.351 0.0139 1.12 0.333 0.00441 0.4 1.0762 0.9035 1272 NINDS_000665 Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B08 compound treatment 0.36 0.0229 1.85 0.347 0.0184 1.67 2.4872 0.9988 1273 NINDS_000666 C[C@@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B09 compound treatment 0.353 0.0159 1.28 0.336 0.00741 0.67 1.3826 0.9545 1274 NINDS_000667 C1CN2C[C@@H](N=C2S1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B10 compound treatment 0.355 0.0179 1.44 0.34 0.0114 1.04 1.7532 0.9867 1275 NINDS_000668 CC(=O)NCCc1c[nH]c2ccc(O)cc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B11 compound treatment 0.366 0.0289 2.33 0.363 0.0344 3.12 3.8559 0.9896 1000129 NINDS_000669 CC1(C)[C@H](CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)OC(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B12 compound treatment 0.367 0.0299 2.41 0.363 0.0344 3.12 3.9128 0.9918 1277 NINDS_000670 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](OC(=O)C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)O[C@H]5CC[C@@]6(C)C(CCC7C6C[C@@H](O)[C@]8(C)[C@H](CC[C@]78O)C9=CC(=O)OC9)C5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B13 compound treatment 0.359 0.0219 1.77 0.346 0.0174 1.58 2.3661 0.9985 1278 NINDS_000671 COc1ccc(cc1O)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@H](C)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B14 compound treatment 0.355 0.0179 1.44 0.345 0.0164 1.49 2.0742 0.9999 1279 NINDS_000672 N[C@@H]([C@@H]1CC(=NO1)Cl)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B15 compound treatment 0.355 0.0179 1.44 0.339 0.0104 0.94 1.6891 0.9788 1280 NINDS_000673 NCCNC(=O)c1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B16 compound treatment 0.36 0.0229 1.85 0.345 0.0164 1.49 2.3589 0.9943 3174477 NINDS_000674 CN[C@H](CC(C)C)C(=O)NC1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6CC(=O)C(NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC1=O)c7ccc(O)c(c7)-c8c(O)cc(O)cc8[C@@H](NC6=O)C(=O)O)c3O[C@@H]9OC(CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B17 compound treatment 0.353 0.0159 1.28 0.34 0.0114 1.04 1.6394 0.9943 1282 NINDS_000675 NS(=O)(=O)c1cc2c(N=CNS2(=O)=O)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B18 compound treatment 0.377 0.0399 3.22 0.375 0.0464 4.21 5.2524 0.9911 3046211 NINDS_000676 CCC(C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C/C=C(\C)/[C@@H](OC4C[C@H](OC)C(O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2)C=C[C@@H]1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B19 compound treatment 0.342 0.00493 0.4 0.345 0.0164 1.49 1.3339 0.8655 1284 NINDS_000677 OC(=O)CN(CC(=O)O)Cc1cc2c(c3ccccc3C(=O)O)c4cc(CN(CC(=O)O)CC(=O)O)c(=O)cc4oc2cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B20 compound treatment 0.34 0.00293 0.24 0.322 -0.00659 -0.6 -0.2562 -0.3982 1285 NINDS_000678 CC[C@@]1(O)C[C@H](OC2CC(C(OC3CC(O)C(OC4CCC(=O)C(C)O4)C(C)O3)C(C)O2)N(C)C)c5c(O)c6C(=O)c7c(O)cccc7C(=O)c6cc5[C@H]1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B21 compound treatment 0.325 -0.0121 -0.97 0.319 -0.00959 -0.87 -1.3029 -0.9985 1286 NINDS_000679 Cc1cc(ccc1OCCOCC[N+](C)(C)Cc2ccccc2)C(C)(C)CC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B22 compound treatment 0.365 0.0279 2.25 0.356 0.0274 2.49 3.3496 0.9987 1287 NINDS_000680 CC(=O)C1CCC2C3CC=C4CC(CC[C@]4(C)C3CC[C@]12C)OS(=O)(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B23 positive control 0.085 -0.252 -20.3 0.083 -0.246 -22.29 -30.1163 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 B24 positive control 0.084 -0.253 -20.38 0.083 -0.246 -22.29 -30.1733 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C01 mock treatment 0.339 0.00193 0.16 0.333 0.00441 0.4 0.3929 0.9154 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C02 mock treatment 0.341 0.00393 0.32 0.323 -0.00559 -0.51 -0.1351 -0.2257 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C03 compound treatment 0.192 -0.145 -11.68 0.184 -0.145 -13.12 -17.541 -0.9983 1288 NINDS_000681 CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O)[C@H](C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)cccc5C(=O)c4cc3[C@H]1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C04 compound treatment 0.35 0.0129 1.04 0.345 0.0164 1.49 1.7895 0.9847 1289 NINDS_000682 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C05 compound treatment 0.349 0.0119 0.96 0.341 0.0124 1.13 1.4758 0.9969 1290 NINDS_000683 OC(=O)c1ccc(cc1)S(=O)(=O)N(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C06 compound treatment 0.354 0.0169 1.36 0.338 0.00941 0.85 1.5679 0.9746 1291 NINDS_000684 CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C07 compound treatment 0.345 0.00793 0.64 0.335 0.00641 0.58 0.8629 0.9989 1292 NINDS_000685 O=c1[nH]cnc2[nH]ncc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C08 compound treatment 0.347 0.00993 0.8 0.34 0.0114 1.04 1.2977 0.9919 1293 NINDS_000686 CC(=O)OCC[N+](C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C09 compound treatment 0.336 -0.00107 -0.09 0.324 -0.00459 -0.42 -0.3556 -0.8352 1294 NINDS_000687 CCN(CC)Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C10 compound treatment 0.339 0.00193 0.16 0.327 -0.00159 -0.14 0.0078 0.0367 1295 NINDS_000688 OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C11 compound treatment 0.348 0.0109 0.88 0.334 0.00541 0.49 0.9696 0.9619 2550 NINDS_000689 O[C@@H]([C@@H](COC(=O)CCC(=O)O)NC(=O)C(Cl)Cl)c1ccc(cc1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C12 compound treatment 0.349 0.0119 0.96 0.333 0.00441 0.4 0.9623 0.9245 1000131 NINDS_000690 C1CCN2CC3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C13 compound treatment 0.35 0.0129 1.04 0.33 0.00141 0.13 0.8267 0.7879 3174481 NINDS_000691 CNC[C@@H](O)c1ccc(O)c(O)c1.OC(C(O)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C14 compound treatment 0.352 0.0149 1.2 0.333 0.00441 0.4 1.1331 0.8941 1297 NINDS_000692 COc1cc(CC=C)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C15 compound treatment 0.467 0.13 10.46 0.427 0.0984 8.93 13.7147 0.9969 1298 NINDS_000693 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C16 compound treatment 0.346 0.00893 0.72 0.337 0.00841 0.76 1.0482 0.9996 1299 NINDS_000694 Nc1ccc(cc1)C(=O)NCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C17 compound treatment 0.347 0.00993 0.8 0.339 0.0104 0.94 1.2335 0.9966 1300 NINDS_000695 OC(=O)c1cccnc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C18 compound treatment 0.36 0.0229 1.85 0.362 0.0334 3.03 3.45 0.9717 1301 NINDS_000696 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C19 compound treatment 0.364 0.0269 2.17 0.362 0.0334 3.03 3.6778 0.9865 1302 NINDS_000697 CC(C)CC1N2C(=O)[C@](NC(=O)C3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(OC2(O)[C@@H]7CCCN7C1=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C20 compound treatment 0.346 0.00893 0.72 0.328 -5.94E-4 -0.05 0.4706 0.6523 1303 NINDS_000698 C[N+]1(CCC2CC1)CC2OC(=O)C(O)(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C21 compound treatment 0.341 0.00393 0.32 0.33 0.00141 0.13 0.3142 0.9202 1304 NINDS_000699 ClC1=C(Cl)C2(Cl)C3C4CC(C5OC54)C3C1(Cl)C2(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C22 compound treatment 0.336 -0.00107 -0.09 0.328 -5.94E-4 -0.05 -0.0988 -0.9748 1305 NINDS_000700 CCOC(=O)O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccc(OC)cc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C23 positive control 0.081 -0.256 -20.62 0.08 -0.249 -22.57 -30.5367 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 C24 positive control 0.083 -0.254 -20.46 0.084 -0.245 -22.2 -30.166 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D01 mock treatment 0.341 0.00393 0.32 0.328 -5.94E-4 -0.05 0.1859 0.5785 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D02 mock treatment 0.34 0.00293 0.24 0.328 -5.94E-4 -0.05 0.1289 0.5321 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D03 compound treatment 0.35 0.0129 1.04 0.339 0.0104 0.94 1.4044 0.9988 3046265 NINDS_000701 Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D04 compound treatment 0.369 0.0319 2.57 0.37 0.0414 3.76 4.476 0.9829 935 NINDS_000702 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D05 compound treatment 0.326 -0.0111 -0.89 0.311 -0.0176 -1.6 -1.7594 -0.962 1307 NINDS_000703 ClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D06 compound treatment 0.348 0.0109 0.88 0.335 0.00641 0.58 1.0337 0.9797 1308 NINDS_000704 CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D07 compound treatment 0.354 0.0169 1.36 0.345 0.0164 1.49 2.0172 0.999 3046268 NINDS_000705 Cc1cc(C2CCCCC2)n(O)c(=O)c1.NCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D08 compound treatment 0.357 0.0199 1.61 0.344 0.0154 1.4 2.1239 0.9976 1310 NINDS_000706 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](OP(=O)(O)O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D09 compound treatment 0.355 0.0179 1.44 0.348 0.0194 1.76 2.2667 0.9951 1311 NINDS_000707 C[C@@]12CCC3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D10 compound treatment 0.353 0.0159 1.28 0.337 0.00841 0.76 1.4468 0.9692 1312 NINDS_000708 C[As](=O)(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D11 compound treatment 0.36 0.0229 1.85 0.346 0.0174 1.58 2.4231 0.997 1313 NINDS_000709 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D12 compound treatment 0.367 0.0299 2.41 0.359 0.0304 2.76 3.6561 0.9977 1314 NINDS_000710 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D13 compound treatment 0.364 0.0269 2.17 0.358 0.0294 2.67 3.421 0.9947 1315 NINDS_000711 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D14 compound treatment 0.351 0.0139 1.12 0.327 -0.00159 -0.14 0.6911 0.6109 1316 NINDS_000712 CC(C)(C)NCC(O)c1ccccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D15 compound treatment 0.355 0.0179 1.44 0.336 0.00741 0.67 1.4965 0.9395 3046321 NINDS_000713 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)C3O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D16 compound treatment 0.332 -0.00507 -0.41 0.329 4.06E-4 0.04 -0.2624 -0.6406 1317 NINDS_000714 Fc1ccc(cc1)C(c2ccccc2)(c3ccccc3F)n4ccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D17 compound treatment 0.353 0.0159 1.28 0.34 0.0114 1.04 1.6394 0.9943 1318 NINDS_000715 CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D18 compound treatment 0.35 0.0129 1.04 0.341 0.0124 1.13 1.5327 0.9992 1319 NINDS_000716 NCCCCN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D19 compound treatment 0.359 0.0219 1.77 0.344 0.0154 1.4 2.2378 0.9933 445 NINDS_000717 NC(=O)c1cccc(N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D20 compound treatment 0.465 0.128 10.3 0.459 0.13 11.84 15.6548 0.9976 2114344 NINDS_000718 CC1=C(O)C(=O)C=C2C1=CC=C3[C@@]2(C)CC[C@@]4(C)[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D21 compound treatment 0.352 0.0149 1.2 0.337 0.00841 0.76 1.3899 0.9759 1321 NINDS_000719 Cc1cc(=O)[nH]c(=S)[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D22 compound treatment 0.403 0.0659 5.31 0.341 0.0124 1.13 4.5506 0.8384 1322 NINDS_000720 COc1cc2ccc(=O)oc2cc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D23 positive control 0.083 -0.254 -20.46 0.082 -0.247 -22.38 -30.2944 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 D24 positive control 0.085 -0.252 -20.3 0.085 -0.244 -22.11 -29.988 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E01 mock treatment 0.333 -0.00407 -0.33 0.324 -0.00459 -0.42 -0.5264 -0.9928 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E02 mock treatment 0.35 0.0129 1.04 0.325 -0.00359 -0.33 0.5058 0.4634 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E03 compound treatment 0.358 0.0209 1.69 0.34 0.0114 1.04 1.9241 0.9726 1323 NINDS_000721 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E04 compound treatment 0.193 -0.144 -11.6 0.191 -0.138 -12.49 -17.0347 -0.9993 1324 NINDS_000722 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E05 compound treatment 0.349 0.0119 0.96 0.343 0.0144 1.31 1.6042 0.9885 1325 NINDS_000723 NC1(CCCC1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E06 compound treatment 0.348 0.0109 0.88 0.338 0.00941 0.85 1.2263 0.9999 1000132 NINDS_000724 CC1(C)C2CCC1(C)C(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E07 compound treatment 0.351 0.0139 1.12 0.338 0.00941 0.85 1.3971 0.9909 1327 NINDS_000725 C[N+](C)(C)CCOC(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E08 compound treatment 0.34 0.00293 0.24 0.334 0.00541 0.49 0.514 0.9438 1328 NINDS_000726 OC(CCN1CCCCC1)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E09 compound treatment 0.339 0.00193 0.16 0.316 -0.0126 -1.14 -0.6982 -0.6052 1329 NINDS_000727 NC(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E10 compound treatment 0.333 -0.00407 -0.33 0.328 -5.94E-4 -0.05 -0.2697 -0.8126 1330 NINDS_000728 ClCCN(CCCl)CCCl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E11 compound treatment 0.359 0.0219 1.77 0.342 0.0134 1.22 2.1094 0.9835 1331 NINDS_000729 CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E12 compound treatment 0.352 0.0149 1.2 0.343 0.0144 1.31 1.775 0.9991 451 NINDS_000730 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E13 compound treatment 0.353 0.0159 1.28 0.344 0.0154 1.4 1.8961 0.9991 1332 NINDS_000731 NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc32 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E14 compound treatment 0.29 -0.0471 -3.79 0.278 -0.0506 -4.59 -5.9274 -0.9955 1333 NINDS_000732 CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC1=O)C(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E15 compound treatment 0.354 0.0169 1.36 0.344 0.0154 1.4 1.953 0.9999 1334 NINDS_000733 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E16 compound treatment 0.346 0.00893 0.72 0.334 0.00541 0.49 0.8557 0.9826 1335 NINDS_000734 COc1cccc(C(=O)c2ccccc2O)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E17 compound treatment 0.35 0.0129 1.04 0.341 0.0124 1.13 1.5327 0.9992 1336 NINDS_000735 CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E18 compound treatment 0.364 0.0269 2.17 0.345 0.0164 1.49 2.5866 0.9832 1337 NINDS_000736 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E19 compound treatment 0.325 -0.0121 -0.97 0.313 -0.0156 -1.42 -1.688 -0.9832 1338 NINDS_000737 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E20 compound treatment 0.346 0.00893 0.72 0.338 0.00941 0.85 1.1124 0.9964 1339 NINDS_000738 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E21 compound treatment 0.367 0.0299 2.41 0.36 0.0314 2.85 3.7202 0.9965 1340 NINDS_000739 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C2=O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E22 compound treatment 0.345 0.00793 0.64 0.344 0.0154 1.4 1.4406 0.937 1341 NINDS_000740 CC(=O)OCC(COC(=O)C)OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E23 positive control 0.082 -0.255 -20.54 0.082 -0.247 -22.38 -30.3513 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 E24 positive control 0.087 -0.25 -20.14 0.087 -0.242 -21.93 -29.7457 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F01 mock treatment 0.332 -0.00507 -0.41 0.324 -0.00459 -0.42 -0.5834 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F02 mock treatment 0.338 9.33E-4 0.08 0.338 0.00941 0.85 0.6569 0.7664 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F03 compound treatment 0.165 -0.172 -13.86 0.159 -0.17 -15.39 -20.683 -0.9986 1342 NINDS_000741 CN(C)C(=S)SSC(=S)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F04 compound treatment 0.355 0.0179 1.44 0.34 0.0114 1.04 1.7532 0.9867 1343 NINDS_000742 COC1=CC(C)[C@@H]2C[C@H]3OC(=O)C[C@H]4C(=C(OC)C(=O)C([C@@]34C)[C@@]2(C)C1=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F05 compound treatment 0.354 0.0169 1.36 0.35 0.0214 1.94 2.3382 0.985 1344 NINDS_000743 CCCC(=O)O[C@@]1(CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F06 compound treatment 0.359 0.0219 1.77 0.359 0.0304 2.76 3.2005 0.9767 1000133 NINDS_000744 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F07 compound treatment 0.353 0.0159 1.28 0.34 0.0114 1.04 1.6394 0.9943 1346 NINDS_000745 CCN(CC)CCNC(=O)COc1ccc(OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F08 compound treatment 0.358 0.0209 1.69 0.345 0.0164 1.49 2.245 0.9981 1347 NINDS_000746 CC1=CCCC2(C)CCC3C(OC(=O)C3=C)C12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F09 compound treatment 0.373 0.0359 2.89 0.358 0.0294 2.67 3.9335 0.9992 1348 NINDS_000747 Clc1ccc(OCC(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F10 compound treatment 0.363 0.0259 2.09 0.349 0.0204 1.85 2.7864 0.9982 3046390 NINDS_000748 CCC(=O)O[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F11 compound treatment 0.357 0.0199 1.61 0.338 0.00941 0.85 1.7388 0.9564 924 NINDS_000749 NC(=N)NC(=N)Nc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F12 compound treatment 0.356 0.0189 1.52 0.338 0.00941 0.85 1.6818 0.9625 3172708 NINDS_000750 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)C(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F13 compound treatment 0.361 0.0239 1.93 0.346 0.0174 1.58 2.48 0.9951 1350 NINDS_000751 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F14 compound treatment 0.193 -0.144 -11.6 0.187 -0.142 -12.85 -17.2915 -0.9987 1351 NINDS_000752 Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]3c(C)cc(N)c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F15 compound treatment 0.375 0.0379 3.05 0.357 0.0284 2.58 3.9832 0.9964 1352 NINDS_000753 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F16 compound treatment 0.388 0.0509 4.1 0.376 0.0474 4.3 5.943 0.9997 1353 NINDS_000754 COC(=O)/C(=C/1\OC(=O)C(C1=O)c2ccccc2)/c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F17 compound treatment 0.353 0.0159 1.28 0.34 0.0114 1.04 1.6394 0.9943 1354 NINDS_000755 OS(=O)(=O)CCS 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F18 compound treatment 0.357 0.0199 1.61 0.343 0.0144 1.31 2.0597 0.9948 1355 NINDS_000756 CC(C)(O)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F19 compound treatment 0.347 0.00993 0.8 0.348 0.0194 1.76 1.8112 0.9362 1356 NINDS_000757 Oc1cccc2cccnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F20 compound treatment 0.353 0.0159 1.28 0.343 0.0144 1.31 1.8319 1.0 1357 NINDS_000758 CCCCN1CCCCC1C(=O)Nc2c(C)cccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F21 compound treatment 0.353 0.0159 1.28 0.342 0.0134 1.22 1.7677 0.9997 1358 NINDS_000759 CN(CCCl)CCCl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F22 compound treatment 0.352 0.0149 1.2 0.34 0.0114 1.04 1.5824 0.9972 1359 NINDS_000760 C[C@H]1C2C(CC3C4CC=C5CC(O)CCC5(C)C4CCC23C)O[C@@]61CCC(C)CN6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F23 positive control 0.084 -0.253 -20.38 0.084 -0.245 -22.2 -30.1091 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 F24 positive control 0.087 -0.25 -20.14 0.087 -0.242 -21.93 -29.7457 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G01 mock treatment 0.324 -0.0131 -1.05 0.324 -0.00459 -0.42 -1.0389 -0.9179 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G02 mock treatment 0.334 -0.00307 -0.25 0.323 -0.00559 -0.51 -0.5337 -0.9452 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G03 compound treatment 0.19 -0.147 -11.84 0.196 -0.133 -12.04 -16.8846 -1.0 1360 NINDS_000761 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G04 compound treatment 0.337 -6.67E-5 -0.01 0.33 0.00141 0.13 0.0865 0.6768 1361 NINDS_000762 Clc1cc(Cl)c(OCC#CI)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G05 compound treatment 0.346 0.00893 0.72 0.332 0.00341 0.31 0.7273 0.9289 1362 NINDS_000763 COc1c2occc2cc3ccc(=O)oc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G06 compound treatment 0.364 0.0269 2.17 0.36 0.0314 2.85 3.5494 0.9909 1363 NINDS_000764 CCOC(=O)CCC(=O)O[C@@H]1[C@H](C[C@@H](C)O[C@H]1O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G07 compound treatment 0.351 0.0139 1.12 0.351 0.0224 2.03 2.2315 0.9607 1364 NINDS_000765 OC(=O)/C(=C/c1cccc(O)c1)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G08 compound treatment 0.317 -0.0201 -1.62 0.305 -0.0236 -2.14 -2.657 -0.9904 1365 NINDS_000766 CN(C)CCC=C1c2ccccc2CCc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G09 compound treatment 0.356 0.0189 1.52 0.348 0.0194 1.76 2.3237 0.9974 3172713 NINDS_000767 CO/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)C)\c3csc(N)n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G10 compound treatment 0.351 0.0139 1.12 0.334 0.00541 0.49 1.1404 0.9312 1367 NINDS_000768 Cc1cc(O)ccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G11 compound treatment 0.372 0.0349 2.81 0.362 0.0334 3.03 4.1333 0.9993 1368 NINDS_000769 CCC(C)C(N)C1=NC(CS1)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NCCCCC2NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4ccccc4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G12 compound treatment 0.356 0.0189 1.52 0.334 0.00541 0.49 1.4251 0.8897 3172714 NINDS_000770 C[n+]1ccccc1/C=N/O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G13 compound treatment 0.323 -0.0141 -1.13 0.324 -0.00459 -0.42 -1.0958 -0.9078 1370 NINDS_000771 C/C=C(/C(=C/C)/c1ccc(O)cc1)\c2ccc(O)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G14 compound treatment 0.351 0.0139 1.12 0.338 0.00941 0.85 1.3971 0.9909 1371 NINDS_000772 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G15 compound treatment 0.352 0.0149 1.2 0.34 0.0114 1.04 1.5824 0.9972 1372 NINDS_000773 OC(=O)c1cccnc1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G16 compound treatment 0.339 0.00193 0.16 0.338 0.00941 0.85 0.7138 0.8225 448 NINDS_000774 Clc1cccc(Cl)c1N=C2NCCN2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G17 compound treatment 0.319 -0.0181 -1.45 0.32 -0.00859 -0.78 -1.5803 -0.9573 1373 NINDS_000775 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G18 compound treatment 0.346 0.00893 0.72 0.341 0.0124 1.13 1.305 0.9766 1374 NINDS_000776 Oc1c(Br)cc(Br)c2cccnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G19 compound treatment 0.34 0.00293 0.24 0.342 0.0134 1.22 1.0275 0.8289 1001324 NINDS_000777 OC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G20 compound treatment 0.391 0.0539 4.34 0.379 0.0504 4.58 6.3063 0.9997 3172716 NINDS_000778 NC(=O)N/N=C/c1ccc(o1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G21 compound treatment 0.353 0.0159 1.28 0.344 0.0154 1.4 1.8961 0.9991 1377 NINDS_000779 CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G22 compound treatment 0.34 0.00293 0.24 0.335 0.00641 0.58 0.5782 0.9212 1378 NINDS_000780 NCCc1ccc(O)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G23 positive control 0.083 -0.254 -20.46 0.083 -0.246 -22.29 -30.2302 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 G24 positive control 0.088 -0.249 -20.06 0.088 -0.241 -21.84 -29.6246 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H01 mock treatment 0.332 -0.00507 -0.41 0.329 4.06E-4 0.04 -0.2624 -0.6406 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H02 mock treatment 0.34 0.00293 0.24 0.329 4.06E-4 0.04 0.1931 0.8077 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H03 compound treatment 0.35 0.0129 1.04 0.342 0.0134 1.22 1.5969 0.997 1000134 NINDS_000781 Nc1ccn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H04 compound treatment 0.283 -0.0541 -4.35 0.269 -0.0596 -5.41 -6.9036 -0.9942 1380 NINDS_000782 NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H05 compound treatment 0.354 0.0169 1.36 0.342 0.0134 1.22 1.8247 0.9984 1381 NINDS_000783 Nc1ccc(cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H06 compound treatment 0.352 0.0149 1.2 0.34 0.0114 1.04 1.5824 0.9972 1382 NINDS_000784 OCCS 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H07 compound treatment 0.371 0.0339 2.73 0.361 0.0324 2.94 4.0122 0.9993 1383 NINDS_000785 CC[C@H]([C@H]1CC[C@H](C)[C@@H](O1)[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2OC3(O[C@@]4(CC[C@](C)(O4)[C@H]5CC[C@](O)(CC)[C@H](C)O5)[C@H](O)C=C3)[C@H](C)C[C@@H]2C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H08 compound treatment 0.362 0.0249 2.01 0.363 0.0344 3.12 3.6281 0.9772 3045655 NINDS_000786 CC(=O)[C@@]1(O)CCC2C3C=C(Cl)C4=CC(=O)[C@@H]5CC5[C@]4(C)C3CC[C@@]21C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H09 compound treatment 0.343 0.00593 0.48 0.345 0.0164 1.49 1.3909 0.8893 1384 NINDS_000787 COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H10 compound treatment 0.331 -0.00607 -0.49 0.322 -0.00659 -0.6 -0.7687 -0.9949 1385 NINDS_000788 C(/C=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H11 compound treatment 0.331 -0.00607 -0.49 0.327 -0.00159 -0.14 -0.4477 -0.8788 1386 NINDS_000789 CN1CC(c2ccccc2)c3cccc(N)c3C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H12 compound treatment 0.323 -0.0141 -1.13 0.312 -0.0166 -1.51 -1.866 -0.9901 1387 NINDS_000790 OC(C1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H13 compound treatment 0.361 0.0239 1.93 0.357 0.0284 2.58 3.186 0.9897 1388 NINDS_000791 Cc1cc(Nc2ccccc2C(=O)O)ccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H14 compound treatment 0.365 0.0279 2.25 0.369 0.0404 3.67 4.184 0.9725 1389 NINDS_000792 CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc4cccnc24)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H15 compound treatment 0.344 0.00693 0.56 0.344 0.0154 1.4 1.3836 0.9189 3045662 NINDS_000793 CC(N)C(O)c1cccc(O)c1.OC(C(O)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H16 compound treatment 0.343 0.00593 0.48 0.337 0.00841 0.76 0.8774 0.9746 1390 NINDS_000794 CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H17 compound treatment 0.349 0.0119 0.96 0.346 0.0174 1.58 1.7967 0.9716 1391 NINDS_000795 CC(N)C(O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H18 compound treatment 0.348 0.0109 0.88 0.329 4.06E-4 0.04 0.6486 0.7361 3172720 NINDS_000796 CNC(C)[C@@H]1CC[C@@H](N)[C@@H](OC2[C@@H](N)C[C@@H](N)[C@H](OC3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H19 compound treatment 0.23 -0.107 -8.62 0.279 -0.0496 -4.5 -9.2796 -0.9541 1393 NINDS_000797 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H20 compound treatment 0.363 0.0259 2.09 0.359 0.0304 2.76 3.4283 0.9905 360 NINDS_000798 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H21 compound treatment 0.351 0.0139 1.12 0.344 0.0154 1.4 1.7822 0.994 1394 NINDS_000799 BrCCC(=O)N1CCN(CC1)C(=O)CCBr 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H22 compound treatment 0.329 -0.00807 -0.65 0.327 -0.00159 -0.14 -0.5616 -0.8439 1395 NINDS_000800 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H23 positive control 0.084 -0.253 -20.38 0.084 -0.245 -22.2 -30.1091 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 H24 positive control 0.088 -0.249 -20.06 0.089 -0.24 -21.75 -29.5604 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I01 mock treatment 0.331 -0.00607 -0.49 0.327 -0.00159 -0.14 -0.4477 -0.8788 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I02 mock treatment 0.342 0.00493 0.4 0.329 4.06E-4 0.04 0.307 0.7694 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I03 compound treatment 0.358 0.0209 1.69 0.343 0.0144 1.31 2.1166 0.9921 1396 NINDS_000801 Cc1cc(O)cc(C)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I04 compound treatment 0.331 -0.00607 -0.49 0.322 -0.00659 -0.6 -0.7687 -0.9949 1397 NINDS_000802 CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I05 compound treatment 0.349 0.0119 0.96 0.34 0.0114 1.04 1.4116 0.9993 1398 NINDS_000803 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I06 compound treatment 0.358 0.0209 1.69 0.338 0.00941 0.85 1.7957 0.9503 1000135 NINDS_000804 CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I07 compound treatment 0.385 0.0479 3.86 0.355 0.0264 2.4 4.4243 0.9737 1400 NINDS_000805 CC(C)[C@@H](C)/C=C/[C@@H](C)C1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I08 compound treatment 0.332 -0.00507 -0.41 0.319 -0.00959 -0.87 -0.9043 -0.9403 2551 NINDS_000806 COc1cc(NC(C)CCCN)c2ncccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I09 compound treatment 0.328 -0.00907 -0.73 0.337 0.00841 0.76 0.0233 0.0221 3046406 NINDS_000807 Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I10 compound treatment 0.291 -0.0461 -3.71 0.286 -0.0426 -3.87 -5.357 -0.9998 1401 NINDS_000808 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I11 compound treatment 0.357 0.0199 1.61 0.33 0.00141 0.13 1.2253 0.7609 1402 NINDS_000809 CC[N+](C)(C)c1cccc(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I12 compound treatment 0.347 0.00993 0.8 0.343 0.0144 1.31 1.4903 0.9722 1403 NINDS_000810 COC(=O)C1=CCCN(C)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I13 compound treatment 0.503 0.166 13.36 0.529 0.2 18.19 22.3115 0.9885 1404 NINDS_000811 Nc1ccc(N=Nc2ccccc2)c(N)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I14 compound treatment 0.34 0.00293 0.24 0.336 0.00741 0.67 0.6424 0.9015 1000136 NINDS_000812 CC12CCC3C(=CCc4cc(O)ccc34)C2CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I15 compound treatment 0.347 0.00993 0.8 0.324 -0.00459 -0.42 0.2708 0.3002 1406 NINDS_000813 NC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I16 compound treatment 0.338 9.33E-4 0.08 0.329 4.06E-4 0.04 0.0792 0.9463 1407 NINDS_000814 NC(COCc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I17 compound treatment 0.342 0.00493 0.4 0.339 0.0104 0.94 0.9488 0.9259 1408 NINDS_000815 NC1(CC2CC3CC(C2)C1)C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I18 compound treatment 0.355 0.0179 1.44 0.342 0.0134 1.22 1.8816 0.9964 1409 NINDS_000816 CCCC(C)(COC(=O)N)COC(=O)NC(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I19 compound treatment 0.358 0.0209 1.69 0.338 0.00941 0.85 1.7957 0.9503 1410 NINDS_000817 S=P(N1CC1)(N2CC2)N3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I20 compound treatment 0.352 0.0149 1.2 0.343 0.0144 1.31 1.775 0.9991 1411 NINDS_000818 COc1ccc(cc1)/C(=C(\c2ccc(OC)cc2)/c3cccc(OC)c3)/Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I21 compound treatment 0.343 0.00593 0.48 0.345 0.0164 1.49 1.3909 0.8893 1412 NINDS_000819 CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I22 compound treatment 0.35 0.0129 1.04 0.342 0.0134 1.22 1.5969 0.997 1413 NINDS_000820 CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I23 positive control 0.083 -0.254 -20.46 0.084 -0.245 -22.2 -30.166 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 I24 positive control 0.091 -0.246 -19.81 0.089 -0.24 -21.75 -29.3896 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J01 mock treatment 0.326 -0.0111 -0.89 0.326 -0.00259 -0.24 -0.7966 -0.8643 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J02 mock treatment 0.356 0.0189 1.52 0.339 0.0104 0.94 1.746 0.9735 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J03 compound treatment 0.346 0.00893 0.72 0.329 4.06E-4 0.04 0.5347 0.7424 1414 NINDS_000821 CC(=O)NO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J04 compound treatment 0.35 0.0129 1.04 0.34 0.0114 1.04 1.4685 1.0 142 NINDS_000822 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J05 compound treatment 0.342 0.00493 0.4 0.332 0.00341 0.31 0.4995 0.9923 1415 NINDS_000823 FC(F)(F)c1cccc(c1)N2CCNCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J06 compound treatment 0.351 0.0139 1.12 0.339 0.0104 0.94 1.4613 0.9963 1416 NINDS_000824 Cn1c(=O)n(C)c2[nH]c(nc2c1=O)C3CCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J07 compound treatment 0.321 -0.0161 -1.29 0.302 -0.0266 -2.41 -2.6218 -0.9573 1417 NINDS_000825 CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J08 compound treatment 0.35 0.0129 1.04 0.344 0.0154 1.4 1.7253 0.9895 383 NINDS_000826 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J09 compound treatment 0.376 0.0389 3.14 0.374 0.0454 4.12 5.1313 0.9909 1418 NINDS_000827 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J10 compound treatment 0.344 0.00693 0.56 0.334 0.00541 0.49 0.7418 0.9979 1419 NINDS_000828 NCCSSCCN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J11 compound treatment 0.356 0.0189 1.52 0.344 0.0154 1.4 2.0669 0.9991 1420 NINDS_000829 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@H]3N(C)CCc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J12 compound treatment 0.472 0.135 10.87 0.461 0.132 12.02 16.1817 0.9987 1421 NINDS_000830 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J13 compound treatment 0.362 0.0249 2.01 0.343 0.0144 1.31 2.3444 0.9784 1422 NINDS_000831 CC1(C)O[C@@H]2C[C@H]3C4C[C@H](F)C5=CC(=O)C=CC5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J14 compound treatment 0.356 0.0189 1.52 0.352 0.0234 2.12 2.5804 0.9868 3172845 NINDS_000832 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)CC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J15 compound treatment 0.347 0.00993 0.8 0.338 0.00941 0.85 1.1694 0.9995 1424 NINDS_000833 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3OC(=O)CCC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J16 compound treatment 0.347 0.00993 0.8 0.333 0.00441 0.4 0.8484 0.9487 1425 NINDS_000834 CC(N)COc1c(C)cccc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J17 compound treatment 0.331 -0.00607 -0.49 0.33 0.00141 0.13 -0.2552 -0.5054 1426 NINDS_000835 ClCCNC(=O)N(CCCl)N=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J18 compound treatment 0.345 0.00793 0.64 0.343 0.0144 1.31 1.3764 0.9457 3172846 NINDS_000836 NC(CO)(CO)CO.OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J19 compound treatment 0.341 0.00393 0.32 0.332 0.00341 0.31 0.4426 0.9999 1428 NINDS_000837 CC(C)NCC(O)COc1cccc2[nH]ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J20 compound treatment 0.345 0.00793 0.64 0.344 0.0154 1.4 1.4406 0.937 1429 NINDS_000838 CCCCOC(=O)c1ccc(N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J21 compound treatment 0.355 0.0179 1.44 0.345 0.0164 1.49 2.0742 0.9999 1430 NINDS_000839 CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC21C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J22 compound treatment 0.35 0.0129 1.04 0.341 0.0124 1.13 1.5327 0.9992 1431 NINDS_000840 Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J23 positive control 0.088 -0.249 -20.06 0.084 -0.245 -22.2 -29.8813 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 J24 positive control 0.09 -0.247 -19.9 0.09 -0.239 -21.66 -29.3823 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K01 mock treatment 0.328 -0.00907 -0.73 0.327 -0.00159 -0.14 -0.6186 -0.8311 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K02 mock treatment 0.337 -6.67E-5 -0.01 0.328 -5.94E-4 -0.05 -0.0419 -0.7737 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K03 compound treatment 0.345 0.00793 0.64 0.334 0.00541 0.49 0.7987 0.9915 1432 NINDS_000841 CN(C)CCOC(C)(c1ccccc1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K04 compound treatment 0.35 0.0129 1.04 0.34 0.0114 1.04 1.4685 1.0 1433 NINDS_000842 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K05 compound treatment 0.307 -0.0301 -2.42 0.289 -0.0396 -3.59 -4.2533 -0.9815 437 NINDS_000843 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K06 compound treatment 0.332 -0.00507 -0.41 0.329 4.06E-4 0.04 -0.2624 -0.6406 1434 NINDS_000844 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K07 compound treatment 0.34 0.00293 0.24 0.327 -0.00159 -0.14 0.0647 0.2337 1435 NINDS_000845 CN1[C@@H]2CC(O)C1CC(C2)OC(=O)[C@H](CO)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K08 compound treatment 0.344 0.00693 0.56 0.331 0.00241 0.22 0.5492 0.9161 1436 NINDS_000846 CCCNC(C)C(=O)Nc1ccccc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K09 compound treatment 0.339 0.00193 0.16 0.334 0.00541 0.49 0.4571 0.8878 1437 NINDS_000847 CS(=O)(=O)OCCCCOS(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K10 compound treatment 0.356 0.0189 1.52 0.339 0.0104 0.94 1.746 0.9735 1438 NINDS_000848 CC(C(=O)O)c1cccc(Oc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K11 compound treatment 0.36 0.0229 1.85 0.352 0.0234 2.12 2.8082 0.9976 1439 NINDS_000849 CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K12 compound treatment 0.352 0.0149 1.2 0.337 0.00841 0.76 1.3899 0.9759 1440 NINDS_000850 COc1ccc2cc(CCC(=O)C)ccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K13 compound treatment 0.317 -0.0201 -1.62 0.31 -0.0186 -1.69 -2.3361 -0.9998 1441 NINDS_000851 CN1CCC(CC1)OC(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K14 compound treatment 0.353 0.0159 1.28 0.336 0.00741 0.67 1.3826 0.9545 1442 NINDS_000852 CC(=O)NC1SCCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K15 compound treatment 0.332 -0.00507 -0.41 0.331 0.00241 0.22 -0.1341 -0.2897 1443 NINDS_000853 CN(C)CCOC(c1ccccc1)c2ccccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K16 compound treatment 0.344 0.00693 0.56 0.342 0.0134 1.22 1.2553 0.9376 1444 NINDS_000854 C1CN=C(N1)C2CCCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K17 compound treatment 0.364 0.0269 2.17 0.365 0.0364 3.3 3.8703 0.9791 336 NINDS_000855 COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K18 compound treatment 0.344 0.00693 0.56 0.341 0.0124 1.13 1.1911 0.9476 1445 NINDS_000856 C/C=C(/C)\C(=O)O[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@@]2(C[C@@]5(O)[C@@H]6CN7C[C@@H](C)CC[C@H]7[C@@](C)(O)[C@@]6(O)[C@@H](O)C[C@@]45O)O[C@@]31O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K19 compound treatment 0.343 0.00593 0.48 0.334 0.00541 0.49 0.6848 0.9999 1446 NINDS_000857 OC(COc1cccc2oc(cc(=O)c12)C(=O)O)COc3cccc4oc(cc(=O)c34)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K20 compound treatment 0.347 0.00993 0.8 0.336 0.00741 0.67 1.041 0.9963 1447 NINDS_000858 NC(=O)c1ccccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K21 compound treatment 0.347 0.00993 0.8 0.341 0.0124 1.13 1.3619 0.986 3172849 NINDS_000859 CN1CCC[C@H]1c2cccnc2.OC(C(O)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K22 compound treatment 0.411 0.0739 5.95 0.407 0.0784 7.12 9.2423 0.9961 1448 NINDS_000860 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K23 positive control 0.085 -0.252 -20.3 0.083 -0.246 -22.29 -30.1163 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 K24 positive control 0.09 -0.247 -19.9 0.09 -0.239 -21.66 -29.3823 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L01 mock treatment 0.344 0.00693 0.56 0.341 0.0124 1.13 1.1911 0.9476 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L02 mock treatment 0.34 0.00293 0.24 0.331 0.00241 0.22 0.3215 0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L03 compound treatment 0.353 0.0159 1.28 0.341 0.0124 1.13 1.7036 0.9979 1449 NINDS_000861 CN1[C@@H](CCC1=O)c2cccnc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L04 compound treatment 0.322 -0.0151 -1.21 0.303 -0.0256 -2.32 -2.5006 -0.9541 1450 NINDS_000862 NCCc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L05 compound treatment 0.437 0.0999 8.05 0.436 0.107 9.75 12.5842 0.9955 1451 NINDS_000863 CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L06 compound treatment 0.337 -6.67E-5 -0.01 0.329 4.06E-4 0.04 0.0223 0.5979 1452 NINDS_000864 CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L07 compound treatment 0.361 0.0239 1.93 0.351 0.0224 2.03 2.8009 0.9996 3172851 NINDS_000865 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L08 compound treatment 0.34 0.00293 0.24 0.337 0.00841 0.76 0.7066 0.8846 1453 NINDS_000866 CN1CCCN=C1/C=C/c2sccc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L09 compound treatment 0.377 0.0399 3.22 0.369 0.0404 3.67 4.8673 0.9979 1454 NINDS_000867 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CCC6C5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L10 compound treatment 0.362 0.0249 2.01 0.35 0.0214 1.94 2.7937 0.9999 1455 NINDS_000868 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3[C@@H](O)C[C@@]21C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L11 compound treatment 0.359 0.0219 1.77 0.347 0.0184 1.67 2.4303 0.9996 1456 NINDS_000869 CC(C)[C@@H](C)/C=C/[C@@H](C)C1CC[C@H]2\C(=C\C=C\3/C[C@@H](O)CC[C@@H]3C)\CCC[C@]12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L12 compound treatment 0.372 0.0349 2.81 0.363 0.0344 3.12 4.1975 0.9986 1457 NINDS_000870 CC(=O)OCC(=O)[C@]12OC3(CCCC3)O[C@@H]2CC4C5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]41C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L13 compound treatment 0.378 0.0409 3.3 0.37 0.0414 3.76 4.9884 0.9979 3172968 NINDS_000871 CCC1NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L14 compound treatment 0.352 0.0149 1.2 0.343 0.0144 1.31 1.775 0.9991 3045683 NINDS_000872 C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.OC(C(O)C(=O)O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L15 compound treatment 0.354 0.0169 1.36 0.346 0.0174 1.58 2.0814 0.9973 1458 NINDS_000873 NC(Cc1ccc(Cl)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L16 compound treatment 0.321 -0.0161 -1.29 0.322 -0.00659 -0.6 -1.3381 -0.9386 1459 NINDS_000874 OC1CCN(CCCN2c3ccccc3Sc4ccc(C#N)cc24)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L17 compound treatment 0.177 -0.16 -12.89 0.173 -0.156 -14.12 -19.1011 -0.999 3172969 NINDS_000875 CC(CNC(=O)CCC/1(C)C(CC(=O)N)C2N([Co]C[C@H]3OC([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)\C1=C(\C)/C/6=N/C(=C\C\7=N/C(=C(/C)\C8=NC2(C)C(C)(CC(=O)N)C8CCC(=O)N)/C(C)(CC(=O)N)C7CCC(=O)N)/C(C)(C)C6CCC(=O)C)OP(=O)(O)O[C@H]9[C@@H](O)C(O[C@@H]9CO)n%10cnc%11cc(C)c(C)cc%10%11 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L18 compound treatment 0.329 -0.00807 -0.65 0.328 -5.94E-4 -0.05 -0.4974 -0.7632 1461 NINDS_000876 CN1CCCN=C1COC(=O)C(O)(C2CCCCC2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L19 compound treatment 0.347 0.00993 0.8 0.342 0.0134 1.22 1.4261 0.9793 1462 NINDS_000877 CC1C(CCC(C)(C)N1C)OC(=O)C(O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L20 compound treatment 0.345 0.00793 0.64 0.346 0.0174 1.58 1.569 0.9206 1463 NINDS_000878 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L21 compound treatment 0.356 0.0189 1.52 0.35 0.0214 1.94 2.452 0.9928 1464 NINDS_000879 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2C3CCC4=CC(=O)CCC4(C)[C@@]3(F)[C@@H](O)CC21C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L22 compound treatment 0.315 -0.0221 -1.78 0.317 -0.0116 -1.05 -2.0006 -0.9687 1465 NINDS_000880 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L23 positive control 0.087 -0.25 -20.14 0.085 -0.244 -22.11 -29.8741 -0.9989 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 L24 positive control 0.09 -0.247 -19.9 0.091 -0.238 -21.57 -29.3182 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M01 mock treatment 0.327 -0.0101 -0.81 0.324 -0.00459 -0.42 -0.8681 -0.9522 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M02 mock treatment 0.329 -0.00807 -0.65 0.323 -0.00559 -0.51 -0.8184 -0.9926 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M03 compound treatment 0.348 0.0109 0.88 0.333 0.00441 0.4 0.9054 0.9363 1466 NINDS_000881 NCCCCC(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M04 compound treatment 0.351 0.0139 1.12 0.337 0.00841 0.76 1.3329 0.9823 1467 NINDS_000882 CCCCOc1ccc(OCCCN2CCOCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M05 compound treatment 0.321 -0.0161 -1.29 0.313 -0.0156 -1.42 -1.9157 -0.999 1468 NINDS_000883 CCCCC(=O)O[C@H]1CCC2C3CCc4cc(O)ccc4C3CC[C@]12C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M06 compound treatment 0.343 0.00593 0.48 0.334 0.00541 0.49 0.6848 0.9999 1469 NINDS_000884 CCC1(CCC(=O)NC1=O)c2ccc(N)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M07 compound treatment 0.342 0.00493 0.4 0.335 0.00641 0.58 0.6921 0.9827 1470 NINDS_000885 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M08 compound treatment 0.338 9.33E-4 0.08 0.329 4.06E-4 0.04 0.0792 0.9463 1471 NINDS_000886 CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M09 compound treatment 0.353 0.0159 1.28 0.336 0.00741 0.67 1.3826 0.9545 1000138 NINDS_000887 CC(C)Cc1ccc(cc1)C(C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M10 compound treatment 0.359 0.0219 1.77 0.359 0.0304 2.76 3.2005 0.9767 1473 NINDS_000888 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M11 compound treatment 0.361 0.0239 1.93 0.355 0.0264 2.4 3.0577 0.9942 3172973 NINDS_000889 COC(=O)[C@@]1(O)OC[C@]2(C3[C@H]4OC[C@@]3([C@@H](C[C@@H]2OC(=O)/C(=C/C)/C)OC(=O)C)C(=O)OC)[C@@H]1[C@@](C)([C@@H]4O)C56O[C@@]6(C)[C@H]7C[C@@H]5OC8OC=C[C@]78O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M12 compound treatment 0.146 -0.191 -15.39 0.15 -0.179 -16.21 -22.3425 -0.9997 1475 NINDS_000890 Cl[Pt]Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M13 compound treatment 0.296 -0.0411 -3.31 0.299 -0.0296 -2.69 -4.2378 -0.9947 1476 NINDS_000891 CNCCCC1(CCC2c3ccccc31)c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M14 compound treatment 0.291 -0.0461 -3.71 0.285 -0.0436 -3.96 -5.4211 -0.9995 1477 NINDS_000892 O=C1O[Pt]OC(=O)C21CCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M15 compound treatment 0.326 -0.0111 -0.89 0.324 -0.00459 -0.42 -0.925 -0.9401 1478 NINDS_000893 Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M16 compound treatment 0.328 -0.00907 -0.73 0.33 0.00141 0.13 -0.426 -0.5748 1479 NINDS_000894 CC(C)NCC(O)c1ccc(O)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M17 compound treatment 0.342 0.00493 0.4 0.331 0.00241 0.22 0.4354 0.9603 1480 NINDS_000895 Clc1ccc2oc(=O)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M18 compound treatment 0.344 0.00693 0.56 0.339 0.0104 0.94 1.0627 0.9685 1481 NINDS_000896 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M19 compound treatment 0.342 0.00493 0.4 0.34 0.0114 1.04 1.013 0.9135 1482 NINDS_000897 CN1CCc2cc3OCOc3cc2C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M20 compound treatment 0.35 0.0129 1.04 0.338 0.00941 0.85 1.3402 0.9951 3000787 NINDS_000898 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M21 compound treatment 0.345 0.00793 0.64 0.339 0.0104 0.94 1.1197 0.9819 1484 NINDS_000899 CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M22 compound treatment 0.342 0.00493 0.4 0.338 0.00941 0.85 0.8846 0.9394 1485 NINDS_000900 CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M23 positive control 0.084 -0.253 -20.38 0.085 -0.244 -22.11 -30.0449 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 M24 positive control 0.09 -0.247 -19.9 0.091 -0.238 -21.57 -29.3182 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N01 mock treatment 0.335 -0.00207 -0.17 0.327 -0.00159 -0.14 -0.22 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N02 mock treatment 0.334 -0.00307 -0.25 0.339 0.0104 0.94 0.4933 0.5053 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N03 compound treatment 0.35 0.0129 1.04 0.34 0.0114 1.04 1.4685 1.0 1486 NINDS_000901 CC(C)NCC(O)COc1ccc(NC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N04 compound treatment 0.349 0.0119 0.96 0.341 0.0124 1.13 1.4758 0.9969 1487 NINDS_000902 CCC(Cc1c(I)cc(I)c(N)c1I)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N05 compound treatment 0.364 0.0269 2.17 0.361 0.0324 2.94 3.6136 0.9888 104 NINDS_000903 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N06 compound treatment 0.345 0.00793 0.64 0.341 0.0124 1.13 1.248 0.9639 1488 NINDS_000904 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C3CC4CC3C=C4)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N07 compound treatment 0.347 0.00993 0.8 0.334 0.00541 0.49 0.9126 0.9725 3172974 NINDS_000905 C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)C4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N08 compound treatment 0.33 -0.00707 -0.57 0.322 -0.00659 -0.6 -0.8256 -0.9997 1489 NINDS_000906 CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N09 compound treatment 0.348 0.0109 0.88 0.335 0.00641 0.58 1.0337 0.9797 1490 NINDS_000907 NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N10 compound treatment 0.354 0.0169 1.36 0.35 0.0214 1.94 2.3382 0.985 3045773 NINDS_000908 CCC(=O)O[C@@H](OP(=O)(CCCCc1ccccc1)CC(=O)N2C[C@@H](C[C@H]2C(=O)O)C3CCCCC3)C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N11 compound treatment 0.266 -0.0711 -5.72 0.26 -0.0686 -6.23 -8.4493 -0.9991 1000139 NINDS_000909 CO[C@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)[C@H]3OCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N12 compound treatment 0.364 0.0269 2.17 0.365 0.0364 3.3 3.8703 0.9791 1493 NINDS_000910 CCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N13 compound treatment 0.348 0.0109 0.88 0.339 0.0104 0.94 1.2905 0.9994 1494 NINDS_000911 C1CN(CCN1)c2ccc3ccccc3n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N14 compound treatment 0.361 0.0239 1.93 0.348 0.0194 1.76 2.6084 0.999 1495 NINDS_000912 OC(=O)CCCCC1CCSS1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N15 compound treatment 0.307 -0.0301 -2.42 0.303 -0.0256 -2.32 -3.3548 -0.9998 1496 NINDS_000913 CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N16 compound treatment 0.347 0.00993 0.8 0.343 0.0144 1.31 1.4903 0.9722 1497 NINDS_000914 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)C2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N17 compound treatment 0.34 0.00293 0.24 0.339 0.0104 0.94 0.835 0.8575 1498 NINDS_000915 OC(=O)P(=O)(O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N18 compound treatment 0.339 0.00193 0.16 0.334 0.00541 0.49 0.4571 0.8878 1499 NINDS_000916 Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N19 compound treatment 0.385 0.0479 3.86 0.366 0.0374 3.4 5.1303 0.998 1500 NINDS_000917 C[C@@H]1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N20 compound treatment 0.348 0.0109 0.88 0.34 0.0114 1.04 1.3547 0.9967 1501 NINDS_000918 NCCc1ccc(O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N21 compound treatment 0.349 0.0119 0.96 0.348 0.0194 1.76 1.9251 0.9594 1502 NINDS_000919 OC(=O)c1c2ccccc2cc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N22 compound treatment 0.347 0.00993 0.8 0.339 0.0104 0.94 1.2335 0.9966 1503 NINDS_000920 Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N23 positive control 0.086 -0.251 -20.22 0.086 -0.243 -22.02 -29.8668 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 N24 positive control 0.09 -0.247 -19.9 0.091 -0.238 -21.57 -29.3182 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O01 mock treatment 0.345 0.00793 0.64 0.343 0.0144 1.31 1.3764 0.9457 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O02 mock treatment 0.339 0.00193 0.16 0.334 0.00541 0.49 0.4571 0.8878 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O03 compound treatment 0.363 0.0259 2.09 0.357 0.0284 2.58 3.2999 0.9945 1504 NINDS_000921 O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O04 compound treatment 0.347 0.00993 0.8 0.346 0.0174 1.58 1.6828 0.9503 1505 NINDS_000922 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O05 compound treatment 0.345 0.00793 0.64 0.345 0.0164 1.49 1.5048 0.9286 1506 NINDS_000923 OCc1cc(=O)c(O)co1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O06 compound treatment 0.347 0.00993 0.8 0.343 0.0144 1.31 1.4903 0.9722 1507 NINDS_000924 CC(N)CCCC(C)(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O07 compound treatment 0.349 0.0119 0.96 0.337 0.00841 0.76 1.219 0.9935 1508 NINDS_000925 CSCCC(NC=O)C(=O)NC(C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O08 compound treatment 0.342 0.00493 0.4 0.343 0.0144 1.31 1.2056 0.8821 142 NINDS_000926 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O09 compound treatment 0.35 0.0129 1.04 0.343 0.0144 1.31 1.6611 0.9936 1509 NINDS_000927 Cn1c(COC(=O)N)ncc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O10 compound treatment 0.339 0.00193 0.16 0.331 0.00241 0.22 0.2645 0.9862 1510 NINDS_000928 CN(C)CCN(Cc1cccs1)c2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O11 compound treatment 0.336 -0.00107 -0.09 0.332 0.00341 0.31 0.1579 0.492 1511 NINDS_000929 Oc1ccc(cc1)C2(OC(=O)c3ccccc32)c4ccc(O)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O12 compound treatment 0.345 0.00793 0.64 0.336 0.00741 0.67 0.9271 0.9997 1512 NINDS_000930 CC(C)NCC(O)c1ccc2ccccc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O13 compound treatment 0.351 0.0139 1.12 0.339 0.0104 0.94 1.4613 0.9963 2431 NINDS_000931 CCN(CC)CCNC(=O)c1ccc(N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O14 compound treatment 0.354 0.0169 1.36 0.339 0.0104 0.94 1.6321 0.9839 1513 NINDS_000932 CCOC(=O)c1ccc(N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O15 compound treatment 0.349 0.0119 0.96 0.348 0.0194 1.76 1.9251 0.9594 1514 NINDS_000933 CC1OC1P(=O)(O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O16 compound treatment 0.354 0.0169 1.36 0.351 0.0224 2.03 2.4023 0.9811 3173095 NINDS_000934 CC(Oc1ccccc1)C(=O)NC2[C@H]3SC(C)(C)C(N3C2=O)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O17 compound treatment 0.347 0.00993 0.8 0.345 0.0164 1.49 1.6186 0.9575 1515 NINDS_000935 CC[C@@H]1[C@@H](Cc2cccn2C)COC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O18 compound treatment 0.335 -0.00207 -0.17 0.336 0.00741 0.67 0.3577 0.5165 1516 NINDS_000936 Nc1c2CCCCc2nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O19 compound treatment 0.349 0.0119 0.96 0.341 0.0124 1.13 1.4758 0.9969 1517 NINDS_000937 CCC1(NC(=O)N(C)C1=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O20 compound treatment 0.347 0.00993 0.8 0.349 0.0204 1.85 1.8754 0.9295 1518 NINDS_000938 OC(=O)c1cc(ccc1O)c2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O21 compound treatment 0.35 0.0129 1.04 0.348 0.0194 1.76 1.982 0.9686 1519 NINDS_000939 CC1(C)OC(=O)NC1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O22 compound treatment 0.353 0.0159 1.28 0.347 0.0184 1.67 2.0887 0.9915 1520 NINDS_000940 CC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O23 positive control 0.086 -0.251 -20.22 0.086 -0.243 -22.02 -29.8668 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 O24 positive control 0.091 -0.246 -19.81 0.092 -0.237 -21.48 -29.197 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P01 mock treatment 0.337 -6.67E-5 -0.01 0.329 4.06E-4 0.04 0.0223 0.5979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P02 mock treatment 0.339 0.00193 0.16 0.333 0.00441 0.4 0.3929 0.9154 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P03 compound treatment 0.339 0.00193 0.16 0.321 -0.00759 -0.69 -0.3773 -0.5339 1000140 NINDS_000941 CC[C@@H]1OC(OC(C(NC(=O)c2nc(nc(N)c2C)C(CC(=O)N)NCC(N)C(=O)N)C(=O)NC(C)C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCc3nc(cs3)c4nc(cs4)C(=O)NCCCCNC(=N)N)c5c[nH]cn5)[C@@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](OC(=O)N)[C@@H]6O)[C@@H](C)[C@@H]1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P04 compound treatment 0.33 -0.00707 -0.57 0.324 -0.00459 -0.42 -0.6972 -0.9883 1522 NINDS_000942 CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P05 compound treatment 0.335 -0.00207 -0.17 0.339 0.0104 0.94 0.5502 0.5737 1523 NINDS_000943 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P06 compound treatment 0.341 0.00393 0.32 0.342 0.0134 1.22 1.0844 0.8624 1524 NINDS_000944 CC(C)Nc1c(C)n(C)n(c2ccccc2)c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P07 compound treatment 0.337 -6.67E-5 -0.01 0.328 -5.94E-4 -0.05 -0.0419 -0.7737 1525 NINDS_000945 CC(CNC(=O)c1ccccc1)C(=O)OCC(=O)[C@]23OC(C)(C)O[C@@H]3CC4C5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]42C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P08 compound treatment 0.338 9.33E-4 0.08 0.336 0.00741 0.67 0.5285 0.7813 1526 NINDS_000946 CC1CCCC(C)N1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P09 compound treatment 0.373 0.0359 2.89 0.372 0.0434 3.94 4.8321 0.9885 1527 NINDS_000947 COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(=C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P10 compound treatment 0.355 0.0179 1.44 0.353 0.0244 2.22 2.5877 0.9785 1528 NINDS_000948 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P11 compound treatment 0.335 -0.00207 -0.17 0.333 0.00441 0.4 0.1651 0.3812 1529 NINDS_000949 COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P12 compound treatment 0.376 0.0389 3.14 0.38 0.0514 4.67 5.5164 0.9813 1530 NINDS_000950 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P13 compound treatment 0.068 -0.269 -21.67 0.067 -0.262 -23.75 -32.1113 -0.999 1531 NINDS_000951 O=c1n([se]c2ccccc12)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P14 compound treatment 0.373 0.0359 2.89 0.372 0.0434 3.94 4.8321 0.9885 1532 NINDS_000952 OC[C@H]1O[C@H](Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P15 compound treatment 0.344 0.00693 0.56 0.338 0.00941 0.85 0.9985 0.9788 1533 NINDS_000953 Cc1cc(CC(=O)O)n(C)c1C(=O)c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P16 compound treatment 0.34 0.00293 0.24 0.34 0.0114 1.04 0.8991 0.8467 1534 NINDS_000954 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P17 compound treatment 0.338 9.33E-4 0.08 0.336 0.00741 0.67 0.5285 0.7813 1535 NINDS_000955 COc1ccc(OC)c(c1)C(O)CNC(=O)CN 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P18 compound treatment 0.436 0.0989 7.97 0.407 0.0784 7.12 10.6659 0.9984 1000141 NINDS_000956 OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P19 compound treatment 0.34 0.00293 0.24 0.333 0.00441 0.4 0.4498 0.9684 1537 NINDS_000957 NC(Cc1ccc(F)cc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P20 compound treatment 0.354 0.0169 1.36 0.345 0.0164 1.49 2.0172 0.999 1538 NINDS_000958 Oc1ccc(c(O)c1)c2oc3cc(O)cc(O)c3c(=O)c2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P21 compound treatment 0.345 0.00793 0.64 0.337 0.00841 0.76 0.9913 0.9961 1539 NINDS_000959 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P22 compound treatment 0.339 0.00193 0.16 0.335 0.00641 0.58 0.5213 0.8659 1000142 NINDS_000960 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P23 positive control 0.087 -0.25 -20.14 0.088 -0.241 -21.84 -29.6815 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.502 P24 positive control 0.094 -0.243 -19.57 0.093 -0.236 -21.39 -28.962 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A01 compound treatment 0.32 -0.0161 -1.29 0.32 -0.0191 -1.74 -2.1429 -0.9895 1344833 MixCom1_000001 Cc1cccc(Cl)c1NC(=S)NCCc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A02 compound treatment 0.315 -0.0211 -1.7 0.322 -0.0171 -1.56 -2.2993 -0.9991 1787937 MixCom1_000002 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A03 compound treatment 0.312 -0.0241 -1.94 0.313 -0.0261 -2.37 -3.0477 -0.995 2069348 MixCom1_000003 CC(NC(=S)Nc1ccc(Cl)cc1)c2ccc(C)cc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A04 compound treatment 0.316 -0.0201 -1.62 0.323 -0.0161 -1.46 -2.1781 -0.9988 1273756 MixCom1_000004 NNC(=O)Cc1ccc(Cl)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A05 compound treatment 0.312 -0.0241 -1.94 0.322 -0.0171 -1.56 -2.4701 -0.994 1179794 MixCom1_000005 O=S(=O)(N1CCN(CCOc2ccccc2)CC1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A06 compound treatment 0.313 -0.0231 -1.86 0.317 -0.0221 -2.01 -2.7341 -0.9992 1371255 MixCom1_000006 OC(=O)c1cccnc1Oc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A07 compound treatment 0.315 -0.0211 -1.7 0.318 -0.0211 -1.92 -2.556 -0.9981 1339310 MixCom1_000007 Fc1cccc(Cl)c1CN2CCC(CC2)NC(=O)c3c(F)cccc3F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A08 compound treatment 0.311 -0.0251 -2.02 0.315 -0.0241 -2.19 -2.9763 -0.9992 1113154 MixCom1_000008 COc1ccc(cc1)C(CC(=O)O)CC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A09 compound treatment 0.317 -0.0191 -1.54 0.322 -0.0171 -1.56 -2.1854 -1.0 2069349 MixCom1_000009 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccccc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A10 compound treatment 0.308 -0.0281 -2.26 0.312 -0.0271 -2.46 -3.3397 -0.9991 1510751 MixCom1_000010 Nc1nnc(SCCO)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A11 compound treatment 0.415 0.0789 6.36 0.416 0.0769 6.98 9.4282 0.9989 2069350 MixCom1_000011 Nc1nc(=S)ss1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A12 compound treatment 0.307 -0.0291 -2.34 0.318 -0.0211 -1.92 -3.0115 -0.9951 2069351 MixCom1_000012 O=C1NN=C(CC1c2ccccc2)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A13 compound treatment 0.308 -0.0281 -2.26 0.316 -0.0231 -2.1 -3.083 -0.9993 1009987 MixCom1_000013 Nc1nc(S)nc(S)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A14 compound treatment 0.303 -0.0331 -2.66 0.315 -0.0241 -2.19 -3.4318 -0.9953 1019912 MixCom1_000014 O=C(N1C=Cc2ccccc2C1C#N)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A15 compound treatment 0.311 -0.0251 -2.02 0.315 -0.0241 -2.19 -2.9763 -0.9992 1008346 MixCom1_000015 OC(C(=O)c1ccco1)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A16 compound treatment 0.308 -0.0281 -2.26 0.318 -0.0211 -1.92 -2.9546 -0.9967 1002188 MixCom1_000016 O=C1NC(C(=N1)c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A17 compound treatment 0.312 -0.0241 -1.94 0.331 -0.00813 -0.74 -1.8924 -0.9125 1949267 MixCom1_000017 CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A18 compound treatment 0.322 -0.0141 -1.13 0.323 -0.0161 -1.46 -1.8365 -0.9919 1602342 MixCom1_000018 CCOc1ccc(C(=O)N)c(SCC(=O)O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A19 compound treatment 0.316 -0.0201 -1.62 0.317 -0.0221 -2.01 -2.5632 -0.9942 2069352 MixCom1_000019 COC(=O)CS(=O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A20 compound treatment 0.691 0.355 28.58 0.689 0.35 31.76 42.6664 0.9986 1005579 MixCom1_000020 CN1CSC(=S)N(C)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A21 compound treatment 0.312 -0.0241 -1.94 0.32 -0.0191 -1.74 -2.5985 -0.9985 1042325 MixCom1_000021 CC(=O)Nc1ccccc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A22 compound treatment 0.314 -0.0221 -1.78 0.327 -0.0121 -1.1 -2.0353 -0.9735 2069353 MixCom1_000022 CCCCCCCCCCCCCCCCCC1N=CCN1CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A23 mock treatment 0.307 -0.0291 -2.34 0.315 -0.0241 -2.19 -3.2041 -0.9995 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 A24 positive control 0.082 -0.254 -20.46 0.082 -0.257 -23.34 -30.9709 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B01 compound treatment 0.339 0.00293 0.24 0.349 0.00987 0.9 0.8003 0.8641 2079645 MixCom1_000023 OC(=O)CSCC(=O)N1CCC(CC1)N2C(=O)Cc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B02 compound treatment 0.341 0.00493 0.4 0.353 0.0139 1.26 1.1709 0.8871 2079646 MixCom1_000024 CCCN1CCC(CC1)N(C2CC2)C(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B03 compound treatment 0.346 0.00993 0.8 0.346 0.00687 0.62 1.0063 0.9924 2079647 MixCom1_000025 OC(=O)c1ccccc1C(=O)N2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B04 compound treatment 0.337 9.33E-4 0.08 0.345 0.00587 0.53 0.4297 0.799 2079648 MixCom1_000026 OC(=O)/C=C\C(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B05 compound treatment 0.345 0.00893 0.72 0.347 0.00787 0.71 1.0136 1.0 2079649 MixCom1_000027 Nc1ccccc1C(=O)N2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B06 compound treatment 0.333 -0.00307 -0.25 0.343 0.00387 0.35 0.0736 0.1714 2079650 MixCom1_000028 OC(=O)CCC(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B07 compound treatment 0.329 -0.00707 -0.57 0.351 0.0119 1.08 0.3593 0.2949 2079651 MixCom1_000029 O=C1Cc2ccccc2N1C3CCNCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B08 compound treatment 0.34 0.00393 0.32 0.345 0.00587 0.53 0.6005 0.9692 2079652 MixCom1_000030 OC(=O)COCC(=O)N(C1CC1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B09 compound treatment 0.343 0.00693 0.56 0.35 0.0109 0.99 1.0923 0.9637 2079653 MixCom1_000031 O=C1Cc2ccccc2N1C3CCN(CCC#N)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B10 compound treatment 0.337 9.33E-4 0.08 0.345 0.00587 0.53 0.4297 0.799 2079654 MixCom1_000032 OC(=O)CCCC(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B11 compound treatment 0.324 -0.0121 -0.97 0.336 -0.00313 -0.28 -0.8882 -0.8773 2079655 MixCom1_000033 OC(COc1ccccc1)CN2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B12 compound treatment 0.339 0.00293 0.24 0.346 0.00687 0.62 0.6078 0.9118 2079656 MixCom1_000034 OC(=O)COCC(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B13 compound treatment 0.356 0.0199 1.61 0.355 0.0159 1.44 2.1534 0.9985 2079657 MixCom1_000035 CC(C)(C)C(=O)N1CCC(CC1)N2C(=O)Cc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B14 compound treatment 0.343 0.00693 0.56 0.346 0.00687 0.62 0.8355 0.9985 2079658 MixCom1_000036 CN1CCC(CC1)N2CCC(CC2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B15 compound treatment 0.344 0.00793 0.64 0.352 0.0129 1.17 1.2776 0.9597 2079659 MixCom1_000037 O=C(N1CCC(CC1)N2C(=O)Cc3ccccc23)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B16 compound treatment 0.335 -0.00107 -0.09 0.345 0.00587 0.53 0.3158 0.5855 2079660 MixCom1_000038 CN1CCC(CC1)N2CCC(CC2)C(=O)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B17 compound treatment 0.364 0.0279 2.25 0.361 0.0219 1.98 2.9941 0.9981 2079661 MixCom1_000039 Clc1ccccc1C(=O)N2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B18 compound treatment 0.327 -0.00907 -0.73 0.343 0.00387 0.35 -0.2681 -0.3309 2079662 MixCom1_000040 CN1CCC(CC1)N2CCC(CC2)C(=O)NCc3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B19 compound treatment 0.342 0.00593 0.48 0.346 0.00687 0.62 0.7786 0.9914 2079663 MixCom1_000041 O=C1Cc2ccccc2N1C3CCN(CC3)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B20 compound treatment 0.336 -6.67E-5 -0.01 0.347 0.00787 0.71 0.5011 0.7018 2079664 MixCom1_000042 CCCCCCCCCCCCNC(=O)C1CCN(CC1)C2CCN(C)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B21 compound treatment 0.364 0.0279 2.25 0.359 0.0199 1.8 2.8657 0.994 2079665 MixCom1_000043 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B22 compound treatment 0.332 -0.00407 -0.33 0.338 -0.00113 -0.1 -0.3043 -0.8865 2079666 MixCom1_000044 CN1CCC(CC1)N(C2CCN(Cc3ccccc3)CC2)C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B23 mock treatment 0.334 -0.00207 -0.17 0.339 -1.33E-4 -0.01 -0.1262 -0.7565 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 B24 positive control 0.082 -0.254 -20.46 0.083 -0.256 -23.25 -30.9067 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C01 compound treatment 0.331 -0.00507 -0.41 0.342 0.00287 0.26 -0.1045 -0.216 2069354 MixCom1_000045 Cc1cccc(Cl)c1NC(=S)NCc2ccncc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C02 compound treatment 0.334 -0.00207 -0.17 0.35 0.0109 0.99 0.5798 0.5796 1210757 MixCom1_000046 Nc1ccc(cc1)S(=O)(=O)N2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C03 compound treatment 0.347 0.0109 0.88 0.337 -0.00213 -0.19 0.4856 0.5387 1297952 MixCom1_000047 O=C1N(CN(CCC#N)CCc2ccccn2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C04 compound treatment 0.359 0.0229 1.85 0.341 0.00187 0.17 1.4257 0.7688 1077740 MixCom1_000048 CC(=O)Nc1c(C)cc(Cl)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C05 compound treatment 0.361 0.0249 2.01 0.352 0.0129 1.17 2.2456 0.9668 1698722 MixCom1_000049 Cc1ccc(cc1)S(=O)(=O)N2CCN(CCOc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C06 compound treatment 0.351 0.0149 1.2 0.328 -0.0111 -1.01 0.1357 0.0864 2069355 MixCom1_000050 COc1ccc(cc1)c2n[nH]cc2/C=N/NC(=S)NC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C07 compound treatment 0.364 0.0279 2.25 0.346 0.00687 0.62 2.0313 0.8703 2069356 MixCom1_000051 CC(C)(C)c1ccc(cc1)C(=O)NNC(=S)Nc2ccc3OCOc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C08 compound treatment 0.368 0.0319 2.57 0.345 0.00587 0.53 2.1949 0.8358 1356512 MixCom1_000052 Cc1sc(NC(=O)CCC(=O)O)nc1c2ccc(C)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C09 compound treatment 0.371 0.0349 2.81 0.346 0.00687 0.62 2.4299 0.8433 1201410 MixCom1_000053 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2c(F)cccc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C10 compound treatment 0.364 0.0279 2.25 0.339 -1.33E-4 -0.01 1.582 0.7033 2069357 MixCom1_000054 Cc1ccc(Sc2ccc(cc2/C=C/3\SC(=S)NC3=O)[N+](=O)[O-])cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C11 compound treatment 0.353 0.0169 1.36 0.336 -0.00313 -0.28 0.7631 0.5478 1019305 MixCom1_000055 CN(C)c1ccc(SC#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C12 compound treatment 0.356 0.0199 1.61 0.341 0.00187 0.17 1.2548 0.7774 2069358 MixCom1_000056 O=C1CCC(=NN1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C13 compound treatment 0.346 0.00993 0.8 0.341 0.00187 0.17 0.6854 0.8383 2069359 MixCom1_000057 CC(=O)Nc1ccc(cc1C(F)(F)F)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C14 compound treatment 0.329 -0.00707 -0.57 0.328 -0.0111 -1.01 -1.117 -0.9631 1004616 MixCom1_000058 Oc1ccc2ccccc2c1CN3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C15 compound treatment 0.345 0.00893 0.72 0.34 8.67E-4 0.08 0.5643 0.7798 2069360 MixCom1_000059 CCC(=O)c1c(OC)cc(OC)cc1C(=O)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C16 compound treatment 0.324 -0.0121 -0.97 0.328 -0.0111 -1.01 -1.4017 -0.9998 2069361 MixCom1_000060 [O-][N+](=O)c1ccc2cc(Br)c3ccccc3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C17 compound treatment 0.342 0.00593 0.48 0.343 0.00387 0.35 0.586 0.9885 1039729 MixCom1_000061 CCc1ccccc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C18 compound treatment 0.349 0.0129 1.04 0.348 0.00887 0.8 1.3055 0.9919 2069362 MixCom1_000062 CC(C)C(=O)Nc1ccc(cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C19 compound treatment 0.336 -6.67E-5 -0.01 0.335 -0.00413 -0.38 -0.2691 -0.7172 2069363 MixCom1_000063 COc1ccc2cc(ccc2c1)/C(=N/O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C20 compound treatment 0.392 0.0559 4.5 0.392 0.0529 4.8 6.5781 0.9995 2069364 MixCom1_000064 CN(C)c1ccc(/C=N/NC(=S)N)c(O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C21 compound treatment 0.343 0.00693 0.56 0.345 0.00587 0.53 0.7713 0.9997 1183869 MixCom1_000065 CC(=O)Nc1cc(Cl)c(Cl)cc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C22 compound treatment 0.339 0.00293 0.24 0.339 -1.33E-4 -0.01 0.1585 0.67 1722884 MixCom1_000066 CCc1ccc(NCN2C(=O)c3ccccc3C2=O)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C23 mock treatment 0.326 -0.0101 -0.81 0.332 -0.00713 -0.65 -1.0311 -0.9938 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 C24 positive control 0.084 -0.252 -20.3 0.083 -0.256 -23.25 -30.7928 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D01 compound treatment 0.35 0.0139 1.12 0.354 0.0149 1.35 1.7476 0.9958 2079667 MixCom1_000067 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3C(=O)Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D02 compound treatment 0.322 -0.0141 -1.13 0.335 -0.00413 -0.38 -1.0663 -0.8936 2079668 MixCom1_000068 CN1CCC(CC1)N(C2CCN(Cc3ccccc3)CC2)C(=O)c4ccccc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D03 compound treatment 0.352 0.0159 1.28 0.352 0.0129 1.17 1.7331 0.9989 2079669 MixCom1_000069 CCNC(=O)N1CCC(CC1)N2C(=O)Cc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D04 compound treatment 0.343 0.00693 0.56 0.34 8.67E-4 0.08 0.4504 0.7988 2079670 MixCom1_000070 CN1CCC(CC1)N(C2CCN(Cc3ccccc3)CC2)C(=O)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D05 compound treatment 0.392 0.0559 4.5 0.371 0.0319 2.89 5.2303 0.9771 2079671 MixCom1_000071 CS(=O)(=O)c1ccc2n(C3CCNCC3)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D06 compound treatment 0.343 0.00693 0.56 0.33 -0.00913 -0.83 -0.1914 -0.1915 2079672 MixCom1_000072 CN1CCC(CC1)N(C2CCN(Cc3ccccc3)CC2)C(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D07 compound treatment 0.382 0.0459 3.7 0.354 0.0149 1.35 3.5697 0.9066 2079673 MixCom1_000073 CC(C)(C)C(=O)N1CCC(CC1)n2c(nc3cc(ccc23)S(=O)(=O)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D08 compound treatment 0.374 0.0379 3.05 0.349 0.00987 0.9 2.7932 0.8775 2079674 MixCom1_000074 C(NCc1ccc2OCCc2c1)C3CCCO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D09 compound treatment 0.392 0.0559 4.5 0.357 0.0179 1.62 4.3317 0.9048 2079675 MixCom1_000075 CS(=O)(=O)c1ccc2n(C3CCN(CC3)C(=O)c4ccc(cc4)C(F)(F)F)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D10 compound treatment 0.379 0.0429 3.46 0.349 0.00987 0.9 3.078 0.8618 2079676 MixCom1_000076 OC(=O)C1CCN(Cc2ccc3OCCc3c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D11 compound treatment 0.408 0.0719 5.79 0.365 0.0259 2.35 5.7562 0.9209 2079677 MixCom1_000077 CS(=O)(=O)c1ccc2n(C3CCN(CC3)C(=O)c4ccc(Cl)cc4)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D12 compound treatment 0.386 0.0499 4.02 0.354 0.0149 1.35 3.7975 0.8953 2079678 MixCom1_000078 C(N(Cc1ccc2OCCc2c1)C3CC3)c4cccnc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D13 compound treatment 0.399 0.0629 5.07 0.364 0.0249 2.26 5.1795 0.9336 2079679 MixCom1_000079 CS(=O)(=O)c1ccc2n(C3CCN(CC3)C(=O)Cc4cc(F)cc(F)c4)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D14 compound treatment 0.355 0.0189 1.52 0.341 0.00187 0.17 1.1979 0.7809 2079680 MixCom1_000080 CCOC(=O)C1CCN(Cc2ccc3OCCc3c2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D15 compound treatment 0.383 0.0469 3.78 0.36 0.0209 1.89 4.0118 0.949 2079681 MixCom1_000081 CS(=O)(=O)c1ccc2n(C3CCN(CC3)C(=O)c4ccc(Cl)nc4)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D16 compound treatment 0.345 0.00893 0.72 0.332 -0.00713 -0.65 0.0508 0.0525 2079682 MixCom1_000082 COc1ccc(CN(Cc2ccc3OCCc3c2)C4CC4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D17 compound treatment 0.416 0.0799 6.44 0.373 0.0339 3.07 6.7252 0.9428 2079683 MixCom1_000083 CS(=O)(=O)c1ccc2n(C3CCN(CC3)S(=O)(=O)c4ccc(Cl)cc4)c(nc2c1)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D18 compound treatment 0.363 0.0269 2.17 0.361 0.0219 1.98 2.9371 0.999 2079684 MixCom1_000084 CC(=O)N1CCC(CC1)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D19 compound treatment 0.367 0.0309 2.49 0.356 0.0169 1.53 2.844 0.9727 2079685 MixCom1_000085 COc1ccc(cc1)S(=O)(=O)N2CCC(CC2)n3c(nc4cc(ccc34)S(=O)(=O)C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D20 compound treatment 0.359 0.0229 1.85 0.342 0.00287 0.26 1.4898 0.7988 2079686 MixCom1_000086 O=C1Cc2ccccc2N1C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D21 compound treatment 0.346 0.00993 0.8 0.342 0.00287 0.26 0.7496 0.8912 2079687 MixCom1_000087 CN1CCC(CC1)N(C2CCN(CCc3ccccc3)CC2)C(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D22 compound treatment 0.353 0.0169 1.36 0.342 0.00287 0.26 1.1482 0.8271 2079688 MixCom1_000088 COc1ccccc1/C=C/2\C(=O)N(C3CCN(Cc4ccccc4)CC3)c5ccccc25 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D23 mock treatment 0.33 -0.00607 -0.49 0.336 -0.00313 -0.28 -0.5466 -0.9669 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 D24 positive control 0.088 -0.248 -19.98 0.085 -0.254 -23.07 -30.4367 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E01 compound treatment 0.331 -0.00507 -0.41 0.337 -0.00213 -0.19 -0.4254 -0.942 2069365 MixCom1_000089 FC(F)(F)c1cccc(NC(=S)N(CCC#N)Cc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E02 compound treatment 0.338 0.00193 0.16 0.35 0.0109 0.99 0.8076 0.8087 2069366 MixCom1_000090 CCCCc1ccc(NC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E03 compound treatment 0.318 -0.0181 -1.45 0.323 -0.0161 -1.46 -2.0643 -1.0 1565677 MixCom1_000091 CCN(CC)c1ccc(NCN2C(=O)c3ccccc3C2=O)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E04 compound treatment 0.334 -0.00207 -0.17 0.34 8.67E-4 0.08 -0.0621 -0.3371 1235554 MixCom1_000092 OC(=O)c1cccnc1Oc2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E05 compound treatment 0.353 0.0169 1.36 0.348 0.00887 0.8 1.5333 0.9684 1618731 MixCom1_000093 Clc1ccccc1S(=O)(=O)N2CCN(CCOc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E06 compound treatment 0.36 0.0239 1.93 0.342 0.00287 0.26 1.5468 0.7954 2069367 MixCom1_000094 Cn1cnc(c1)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E07 compound treatment 0.398 0.0619 4.99 0.367 0.0279 2.53 5.3152 0.9505 1246976 MixCom1_000095 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccc(Cl)cc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E08 compound treatment 0.381 0.0449 3.62 0.351 0.0119 1.08 3.3202 0.8795 1126518 MixCom1_000096 Cc1ccc(CSc2nnc(N)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E09 compound treatment 0.473 0.137 11.03 0.427 0.0879 7.98 13.4368 0.9874 2069368 MixCom1_000097 CNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E10 compound treatment 0.395 0.0589 4.75 0.35 0.0109 0.99 4.0532 0.8362 2069369 MixCom1_000098 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)c(/C=C\3/SC(=S)NC3=O)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E11 compound treatment 0.376 0.0399 3.22 0.341 0.00187 0.17 2.3936 0.7433 2069370 MixCom1_000099 CSc1nnc(S)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E12 compound treatment 0.388 0.0519 4.18 0.341 0.00187 0.17 3.0769 0.7352 2069371 MixCom1_000100 Clc1c[nH]c(=O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E13 compound treatment 0.386 0.0499 4.02 0.346 0.00687 0.62 3.284 0.8071 2069372 MixCom1_000101 CC(=O)Nc1ccc(I)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E14 compound treatment 0.342 0.00593 0.48 0.335 -0.00413 -0.38 0.0726 0.1194 1014052 MixCom1_000102 N#CC(N1CCCCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E15 compound treatment 0.373 0.0369 2.97 0.348 0.00887 0.8 2.6721 0.8673 1035271 MixCom1_000103 CC(=O)Nc1ccc(OCC=C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E16 compound treatment 0.347 0.0109 0.88 0.338 -0.00113 -0.1 0.5498 0.6203 1696626 MixCom1_000104 Cc1cc(cc(C)c1O)C2(CCCCC2)c3cc(C)c(O)c(C)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E17 compound treatment 0.359 0.0229 1.85 0.35 0.0109 0.99 2.0033 0.9569 2069373 MixCom1_000105 CC(=O)Nc1ccc(Br)cc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E18 compound treatment 0.356 0.0199 1.61 0.35 0.0109 0.99 1.8325 0.9727 1526931 MixCom1_000106 OC(=O)c1ccccc1C(=O)c2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E19 compound treatment 0.339 0.00293 0.24 0.34 8.67E-4 0.08 0.2227 0.8943 2069374 MixCom1_000107 C/C(=N\O)/c1ccc2c(c1)C(C)(C)CCC2(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E20 compound treatment 0.347 0.0109 0.88 0.341 0.00187 0.17 0.7424 0.828 1056662 MixCom1_000108 Cc1ccc(cc1)S(=O)(=O)OCC(C)(C)COS(=O)(=O)c2ccc(C)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E21 compound treatment 0.367 0.0309 2.49 0.354 0.0149 1.35 2.7156 0.9586 1016071 MixCom1_000109 CS(=O)(=O)Nc1ccccc1NS(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E22 compound treatment 0.36 0.0239 1.93 0.341 0.00187 0.17 1.4826 0.7663 1008547 MixCom1_000110 OCCN(CCO)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E23 mock treatment 0.332 -0.00407 -0.33 0.337 -0.00213 -0.19 -0.3685 -0.9686 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 E24 positive control 0.088 -0.248 -19.98 0.087 -0.252 -22.89 -30.3083 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F01 compound treatment 0.317 -0.0191 -1.54 0.333 -0.00613 -0.56 -1.4793 -0.9058 2079689 MixCom1_000111 CN1CCC(CC1)N(C2CCN(CCc3ccccc3)CC2)C(=O)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F02 compound treatment 0.328 -0.00807 -0.65 0.34 8.67E-4 0.08 -0.4037 -0.617 2079690 MixCom1_000112 O=C/1N(C2CCN(Cc3ccccc3)CC2)c4ccccc4\C1=C\c5ccccn5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F03 compound treatment 0.329 -0.00707 -0.57 0.341 0.00187 0.17 -0.2826 -0.4759 2079691 MixCom1_000113 CN1CCC(CC1)N(C2CCN(CCc3ccccc3)CC2)C(=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F04 compound treatment 0.337 9.33E-4 0.08 0.352 0.0129 1.17 0.879 0.7511 2079692 MixCom1_000114 NC(=O)CCc1ccc2OCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F05 compound treatment 0.323 -0.0131 -1.05 0.339 -1.33E-4 -0.01 -0.7526 -0.7152 2079693 MixCom1_000115 CN1CCC(CC1)N(C2CCN(CCc3ccccc3)CC2)S(=O)(=O)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F06 compound treatment 0.358 0.0219 1.77 0.355 0.0159 1.44 2.2673 0.9949 2079694 MixCom1_000116 O=C(CCc1ccc2OCCc2c1)Nc3cccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F07 compound treatment 0.356 0.0199 1.61 0.353 0.0139 1.26 2.0251 0.9928 2079695 MixCom1_000117 OC(=O)CCc1nc(no1)c2cnccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F08 compound treatment 0.38 0.0439 3.54 0.357 0.0179 1.62 3.6484 0.9374 2079696 MixCom1_000118 CN1CCN(CC1)C(=O)CCc2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F09 compound treatment 0.384 0.0479 3.86 0.358 0.0189 1.71 3.9403 0.9331 2079697 MixCom1_000119 CCCNC(=O)CCc1nc(no1)c2cnccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F10 compound treatment 0.405 0.0689 5.55 0.359 0.0199 1.8 5.2003 0.891 2079698 MixCom1_000120 O=C(CCc1ccc2OCCc2c1)N3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F11 compound treatment 0.396 0.0599 4.83 0.353 0.0139 1.26 4.3027 0.8627 2079699 MixCom1_000121 O=C(CCc1nc(no1)c2cnccn2)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F12 compound treatment 0.382 0.0459 3.7 0.35 0.0109 0.99 3.313 0.8654 2079700 MixCom1_000122 COc1ccc(OC)c(NC(=O)CCc2ccc3OCCc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F13 compound treatment 0.394 0.0579 4.67 0.353 0.0139 1.26 4.1888 0.8669 2079701 MixCom1_000123 FC(F)(F)c1cccc(CNC(=O)CCc2nc(no2)c3cnccn3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F14 compound treatment 0.363 0.0269 2.17 0.341 0.00187 0.17 1.6534 0.76 2079702 MixCom1_000124 CN1CCC(CC1)N(C2CC2)C(=O)CCc3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F15 compound treatment 0.385 0.0489 3.94 0.366 0.0269 2.44 4.5107 0.9734 2079703 MixCom1_000125 O=C(CCc1nc(no1)c2cnccn2)N3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F16 compound treatment 0.386 0.0499 4.02 0.368 0.0289 2.62 4.6961 0.9785 2079704 MixCom1_000126 Clc1ccc(NC(=O)CCc2ccc3OCCc3c2)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F17 compound treatment 0.368 0.0319 2.57 0.349 0.00987 0.9 2.4516 0.9003 2079705 MixCom1_000127 OC(=O)CCCc1nc(no1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F18 compound treatment 0.387 0.0509 4.1 0.369 0.0299 2.71 4.8172 0.9798 2079706 MixCom1_000128 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCc3ccc4OCCc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F19 compound treatment 0.372 0.0359 2.89 0.352 0.0129 1.17 2.8719 0.9204 2079707 MixCom1_000129 CCCNC(=O)CCCc1nc(no1)c2cccs2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F20 compound treatment 0.369 0.0329 2.65 0.352 0.0129 1.17 2.7011 0.9321 2079708 MixCom1_000130 OC(=O)C1CCN(Cc2ccc(s2)c3cccs3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F21 compound treatment 0.384 0.0479 3.86 0.362 0.0229 2.08 4.1971 0.9577 2079709 MixCom1_000131 O=C(CCCc1nc(no1)c2cccs2)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F22 compound treatment 0.353 0.0169 1.36 0.345 0.00587 0.53 1.3408 0.9159 2079710 MixCom1_000132 C(N1CCc2ccccc2C1)c3ccc(s3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F23 mock treatment 0.337 9.33E-4 0.08 0.338 -0.00113 -0.1 -0.0196 -0.1538 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 F24 positive control 0.087 -0.249 -20.06 0.087 -0.252 -22.89 -30.3653 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G01 compound treatment 0.339 0.00293 0.24 0.336 -0.00313 -0.28 -0.0341 -0.0922 2069375 MixCom1_000133 O=C1N(CN(CCC#N)Cc2ccccc2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G02 compound treatment 0.34 0.00393 0.32 0.345 0.00587 0.53 0.6005 0.9692 2069376 MixCom1_000134 CCCCc1ccc(NC(=O)C)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G03 compound treatment 0.319 -0.0171 -1.37 0.332 -0.00713 -0.65 -1.4296 -0.941 2069377 MixCom1_000135 Clc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G04 compound treatment 0.345 0.00893 0.72 0.345 0.00587 0.53 0.8852 0.989 1183843 MixCom1_000136 CCCCc1ccc(cc1)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G05 compound treatment 0.358 0.0219 1.77 0.362 0.0229 2.08 2.7166 0.9968 1456855 MixCom1_000137 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CCOc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G06 compound treatment 0.339 0.00293 0.24 0.347 0.00787 0.71 0.6719 0.8934 1698633 MixCom1_000138 Cc1c(Cl)cc(F)cc1S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G07 compound treatment 0.347 0.0109 0.88 0.35 0.0109 0.99 1.32 0.9984 1363199 MixCom1_000139 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)Nc2ccc(OCc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G08 compound treatment 0.367 0.0309 2.49 0.351 0.0119 1.08 2.523 0.9297 2069378 MixCom1_000140 Clc1ccc(CSc2nnc(s2)n3cccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G09 compound treatment 0.385 0.0489 3.94 0.358 0.0189 1.71 3.9973 0.9304 2069379 MixCom1_000141 CC(C)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G10 compound treatment 0.401 0.0649 5.23 0.36 0.0209 1.89 5.0367 0.9057 2069380 MixCom1_000142 CS/C(=N\C#N)/NCCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G11 compound treatment 0.401 0.0649 5.23 0.35 0.0109 0.99 4.3948 0.8259 1035181 MixCom1_000143 Cc1ccc(cc1)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G12 compound treatment 0.362 0.0259 2.09 0.353 0.0139 1.26 2.3667 0.9706 2069381 MixCom1_000144 N#CC1(CCCCC1)NNC2(CCCCC2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G13 compound treatment 0.38 0.0439 3.54 0.349 0.00987 0.9 3.1349 0.859 2069382 MixCom1_000145 CC(=O)Nc1ccc(C#N)cc1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G14 compound treatment 0.378 0.0419 3.38 0.352 0.0129 1.17 3.2136 0.8994 1044849 MixCom1_000146 N#CC(N1CCOCC1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G15 compound treatment 0.369 0.0329 2.65 0.351 0.0119 1.08 2.6369 0.9212 2069383 MixCom1_000147 OC(=O)c1ccccc1C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G16 compound treatment 0.62 0.284 22.86 0.592 0.253 22.95 32.3977 1.0 1030489 MixCom1_000148 CC1C(=C(C)NC(=C1C(=O)C)C)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G17 compound treatment 0.368 0.0319 2.57 0.35 0.0109 0.99 2.5158 0.9134 2069384 MixCom1_000149 CC(=O)Nc1ccc(C#N)cc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G18 compound treatment 0.364 0.0279 2.25 0.35 0.0109 0.99 2.288 0.9316 2069385 MixCom1_000150 CC(NCc1ccccc1)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G19 compound treatment 0.363 0.0269 2.17 0.338 -0.00113 -0.1 1.4609 0.6728 1079214 MixCom1_000151 CC(=O)Nc1ccc2CCCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G20 compound treatment 0.361 0.0249 2.01 0.349 0.00987 0.9 2.053 0.9338 2069386 MixCom1_000152 Cc1cc(C)c([N+](=O)[O-])c(C)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G21 compound treatment 0.379 0.0429 3.46 0.363 0.0239 2.17 3.9765 0.9747 2069387 MixCom1_000153 Cc1nc2cc(Cl)c(Cl)cc2[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G22 compound treatment 0.351 0.0149 1.2 0.345 0.00587 0.53 1.2269 0.9329 1110132 MixCom1_000154 OC(=O)CCN1C(=O)c2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G23 mock treatment 0.336 -6.67E-5 -0.01 0.351 0.0119 1.08 0.7579 0.7036 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 G24 positive control 0.088 -0.248 -19.98 0.088 -0.251 -22.8 -30.2441 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H01 compound treatment 0.348 0.0119 0.96 0.348 0.00887 0.8 1.2486 0.9961 2079711 MixCom1_000155 Clc1ccc(CNC(=O)CCCc2nc(no2)c3cccs3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H02 compound treatment 0.34 0.00393 0.32 0.357 0.0179 1.62 1.3707 0.8295 2079712 MixCom1_000156 CCOC(=O)C1CCN(Cc2ccc(s2)c3cccs3)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H03 compound treatment 0.354 0.0179 1.44 0.357 0.0179 1.62 2.1679 0.9983 2079713 MixCom1_000157 Clc1cccc(c1)N2CCN(CC2)C(=O)CCCc3nc(no3)c4cccs4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H04 compound treatment 0.334 -0.00207 -0.17 0.341 0.00187 0.17 0.0021 0.009 2079714 MixCom1_000158 Fc1ccc(cc1)N2CCN(Cc3ccc(s3)c4cccs4)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H05 compound treatment 0.337 9.33E-4 0.08 0.346 0.00687 0.62 0.4939 0.7867 2079715 MixCom1_000159 CN1CCC(CC1)N2C(=O)Cc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H06 compound treatment 0.315 -0.0211 -1.7 0.337 -0.00213 -0.19 -1.3365 -0.7827 2079716 MixCom1_000160 Clc1ccccc1C(=O)N(Cc2ccc(s2)c3cccs3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H07 compound treatment 0.324 -0.0121 -0.97 0.345 0.00587 0.53 -0.3105 -0.2803 2079717 MixCom1_000161 CN1CCC(CC1)N2C(=O)/C(=C\c3ccc(Cl)cc3)/c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H08 compound treatment 0.321 -0.0151 -1.21 0.326 -0.0131 -1.19 -1.7009 -1.0 2079718 MixCom1_000162 Clc1ccc(cn1)C(=O)N(Cc2ccc(s2)c3cccs3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H09 compound treatment 0.388 0.0519 4.18 0.361 0.0219 1.98 4.3606 0.942 2079719 MixCom1_000163 COc1ccccc1/C=C/2\C(=O)N(C3CCN(C)CC3)c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H10 compound treatment 0.402 0.0659 5.31 0.368 0.0289 2.62 5.6071 0.947 2079720 MixCom1_000164 CC(=O)Oc1ccccc1C(=O)N(Cc2ccc(s2)c3cccs3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H11 compound treatment 0.411 0.0749 6.03 0.368 0.0289 2.62 6.1196 0.9302 2079721 MixCom1_000165 CN1CCC(CC1)N2C(=O)/C(=C\c3cccnc3)/c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H12 compound treatment 0.357 0.0209 1.69 0.324 -0.0151 -1.37 0.2206 0.1015 2079722 MixCom1_000166 FC(F)(F)c1cccc(c1)C(=O)N(Cc2ccc(s2)c3cccs3)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H13 compound treatment 0.492 0.156 12.56 0.466 0.127 11.52 17.0219 0.9991 2079723 MixCom1_000167 CN1CCC(CC1)N2C(=O)/C(=C\c3ccco3)/c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H14 compound treatment 0.381 0.0449 3.62 0.352 0.0129 1.17 3.3844 0.8901 2079724 MixCom1_000168 C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc(s4)c5cccs5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H15 compound treatment 0.369 0.0329 2.65 0.345 0.00587 0.53 2.2518 0.8325 2079725 MixCom1_000169 C(NC1CC1)c2ccc3OCCc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H16 compound treatment 0.369 0.0329 2.65 0.342 0.00287 0.26 2.0592 0.7728 2079726 MixCom1_000170 OC(=O)C1CCN(Cc2ccccn2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H17 compound treatment 0.379 0.0429 3.46 0.356 0.0169 1.53 3.5272 0.9329 2079727 MixCom1_000171 OC(=O)/C=C\C(=O)N(Cc1ccc2OCCc2c1)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H18 compound treatment 0.357 0.0209 1.69 0.352 0.0129 1.17 2.0178 0.9839 2079728 MixCom1_000172 O=C(NC1CCCCC1)C2CCN(Cc3ccccn3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H19 compound treatment 0.365 0.0289 2.33 0.35 0.0109 0.99 2.345 0.9268 2079729 MixCom1_000173 OC(=O)CCC(=O)N(Cc1ccc2OCCc2c1)C3CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H20 compound treatment 0.368 0.0319 2.57 0.355 0.0159 1.44 2.8367 0.9625 2079730 MixCom1_000174 O=C(C1CCN(Cc2ccccn2)CC1)N3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H21 compound treatment 0.353 0.0169 1.36 0.347 0.00787 0.71 1.4691 0.9544 2079731 MixCom1_000175 Clc1ccc(cc1)C(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H22 compound treatment 0.353 0.0169 1.36 0.346 0.00687 0.62 1.4049 0.9371 2079732 MixCom1_000176 FC(F)(F)c1cccc(CNC(=O)C2CCN(Cc3ccccn3)CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H23 mock treatment 0.336 -6.67E-5 -0.01 0.343 0.00387 0.35 0.2444 0.6962 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 H24 positive control 0.09 -0.246 -19.81 0.089 -0.25 -22.7 -30.0661 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I01 compound treatment 0.343 0.00693 0.56 0.344 0.00487 0.44 0.7072 0.9933 2069388 MixCom1_000177 O=C1N(CN(CCC#N)C2CCCCC2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I02 compound treatment 0.337 9.33E-4 0.08 0.351 0.0119 1.08 0.8148 0.7546 1049619 MixCom1_000178 CN(C(=S)N)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I03 compound treatment 0.34 0.00393 0.32 0.353 0.0139 1.26 1.114 0.8583 2069389 MixCom1_000179 CCN(CCC#N)C(=S)Nc1cccc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I04 compound treatment 0.337 9.33E-4 0.08 0.347 0.00787 0.71 0.5581 0.7772 1466450 MixCom1_000180 COC(=O)c1ccc(OC)c(OC2CCCC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I05 compound treatment 0.343 0.00693 0.56 0.361 0.0219 1.98 1.7983 0.8722 1337971 MixCom1_000181 Fc1ccc(c(F)c1)S(=O)(=O)N2CCN(CCOc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I06 compound treatment 0.337 9.33E-4 0.08 0.345 0.00587 0.53 0.4297 0.799 2069390 MixCom1_000182 N/C(=N\O)/Cc1ccc(F)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I07 compound treatment 0.34 0.00393 0.32 0.358 0.0189 1.71 1.4349 0.8239 1531113 MixCom1_000183 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)Nc2cc(Cl)cc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I08 compound treatment 0.382 0.0459 3.7 0.367 0.0279 2.53 4.4041 0.9828 2069391 MixCom1_000184 [O-][N+](=O)c1ccc(CSc2nnc(s2)n3cccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I09 compound treatment 0.385 0.0489 3.94 0.343 0.00387 0.35 3.0345 0.7671 2069392 MixCom1_000185 Cn1c(=S)[nH]c2cc(ccc12)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I10 compound treatment 0.436 0.0999 8.05 0.385 0.0459 4.16 8.6342 0.953 2069393 MixCom1_000186 CCCSc1ccc([N+](=O)[O-])c(/N=C(/NCCS(=O)(=O)O)\NC(=O)OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I11 compound treatment 0.404 0.0679 5.47 0.356 0.0169 1.53 4.9508 0.8715 1114641 MixCom1_000187 OC(=O)CCC(=O)c1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I12 compound treatment 0.395 0.0589 4.75 0.348 0.00887 0.8 3.9248 0.8154 1008972 MixCom1_000188 OCC1(CO)CCCC(CO)(CO)C1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I13 compound treatment 0.4 0.0639 5.15 0.35 0.0109 0.99 4.3379 0.8275 2069394 MixCom1_000189 CC(=O)c1ccc(C#N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I14 compound treatment 0.405 0.0689 5.55 0.363 0.0239 2.17 5.457 0.9158 1386343 MixCom1_000190 OCCN(CCO)C(C#N)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I15 compound treatment 0.381 0.0449 3.62 0.353 0.0139 1.26 3.4486 0.9002 1109655 MixCom1_000191 CC(=O)OCC(=O)c1ccc(Br)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I16 compound treatment 0.38 0.0439 3.54 0.353 0.0139 1.26 3.3916 0.9032 2069395 MixCom1_000192 C(COc1ccccn1)Oc2ccccn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I17 compound treatment 0.378 0.0419 3.38 0.355 0.0159 1.44 3.4061 0.9278 2069396 MixCom1_000193 OC(=O)c1ccc(C(=O)O)c(OC(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I18 compound treatment 0.393 0.0569 4.58 0.374 0.0349 3.16 5.4798 0.9836 1720440 MixCom1_000194 CCOC(=O)C1=C(C)NC(=C(C1C)C(=O)OCC)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I19 compound treatment 0.363 0.0269 2.17 0.351 0.0119 1.08 2.2953 0.9478 2069397 MixCom1_000195 CC(=O)Nc1ccc2CCCc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I20 compound treatment 0.576 0.24 19.32 0.531 0.192 17.42 25.977 0.9987 1013653 MixCom1_000196 [O-][N+](=O)c1ccc(N2CCCCC2)c(c1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I21 compound treatment 0.36 0.0239 1.93 0.351 0.0119 1.08 2.1244 0.9622 2069398 MixCom1_000197 CC(=O)Nc1ccc(Cl)cc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I22 compound treatment 0.354 0.0179 1.44 0.358 0.0189 1.71 2.2321 0.9964 2069399 MixCom1_000198 CCCCCCCCCCCC1=NCCN1CCO 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I23 mock treatment 0.349 0.0129 1.04 0.346 0.00687 0.62 1.1772 0.9699 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 I24 positive control 0.09 -0.246 -19.81 0.088 -0.251 -22.8 -30.1303 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J01 compound treatment 0.345 0.00893 0.72 0.346 0.00687 0.62 0.9494 0.9974 2079733 MixCom1_000199 OC(=O)c1ccccc1C(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J02 compound treatment 0.348 0.0119 0.96 0.35 0.0109 0.99 1.377 0.9999 2079734 MixCom1_000200 OC(=O)C1CCN(Cc2ccncc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J03 compound treatment 0.301 -0.0351 -2.82 0.32 -0.0191 -1.74 -3.2248 -0.9727 2079735 MixCom1_000201 COc1ccc(cc1)S(=O)(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J04 compound treatment 0.339 0.00293 0.24 0.352 0.0129 1.17 0.9929 0.8332 2079736 MixCom1_000202 CC(NC(=O)C1CCN(Cc2ccncc2)CC1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J05 compound treatment 0.338 0.00193 0.16 0.352 0.0129 1.17 0.9359 0.7943 2079737 MixCom1_000203 FC(F)(F)c1ccc(cc1)C(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J06 compound treatment 0.342 0.00593 0.48 0.359 0.0199 1.8 1.613 0.8646 2079738 MixCom1_000204 Clc1ccc(CNC(=O)C2CCN(Cc3ccncc3)CC2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J07 compound treatment 0.347 0.0109 0.88 0.361 0.0219 1.98 2.0261 0.9331 2079739 MixCom1_000205 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J08 compound treatment 0.391 0.0549 4.42 0.358 0.0189 1.71 4.3389 0.9147 2079740 MixCom1_000206 O=C(C1CCN(Cc2ccncc2)CC1)N3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J09 compound treatment 0.393 0.0569 4.58 0.354 0.0149 1.35 4.196 0.878 2079741 MixCom1_000207 Cc1ccc(cc1)S(=O)(=O)NC(=O)N(Cc2ccc3OCCc3c2)C4CC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J10 compound treatment 0.394 0.0579 4.67 0.345 0.00587 0.53 3.6753 0.7827 2079742 MixCom1_000208 OC(=O)C1CCN(Cc2cccnc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J11 compound treatment 0.417 0.0809 6.52 0.365 0.0259 2.35 6.2687 0.9049 2079743 MixCom1_000209 CC1=NC2(CCN(CC2)C(=O)c3ccccc3N)N=C1c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J12 compound treatment 0.396 0.0599 4.83 0.354 0.0149 1.35 4.3669 0.8714 2079744 MixCom1_000210 O=C(NCCc1ccccc1)C2CCN(Cc3cccnc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J13 compound treatment 0.423 0.0869 7.0 0.359 0.0199 1.8 6.2252 0.8611 2079745 MixCom1_000211 CCNC(=O)Nc1ccccc1C(=O)N2CCC3(CC2)N=C(C)C(=N3)c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J14 compound treatment 0.388 0.0519 4.18 0.347 0.00787 0.71 3.462 0.816 2079746 MixCom1_000212 Clc1cccc(CNC(=O)C2CCN(Cc3cccnc3)CC2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J15 compound treatment 0.408 0.0719 5.79 0.349 0.00987 0.9 4.7292 0.8068 2079747 MixCom1_000213 CC1=NC2(CCN(CC2)C(=O)c3ccccc3NC(=O)C(C)(C)C)N=C1c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J16 compound treatment 0.411 0.0749 6.03 0.37 0.0309 2.8 6.2479 0.9391 2079748 MixCom1_000214 CCCCCCCCCCCCNC(=O)C1CCN(Cc2cccnc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J17 compound treatment 0.389 0.0529 4.26 0.363 0.0239 2.17 4.546 0.9507 2079749 MixCom1_000215 CC1=NC2(CCN(CC2)C(=O)c3ccccc3NS(=O)(=O)C)N=C1c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J18 compound treatment 0.379 0.0429 3.46 0.364 0.0249 2.26 4.0407 0.9787 2079750 MixCom1_000216 O=C(C1CCN(Cc2cccnc2)CC1)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J19 compound treatment 0.355 0.0189 1.52 0.349 0.00987 0.9 1.7114 0.9678 2079751 MixCom1_000217 COc1cc(OC)nc(n1)c2n[nH]c(=S)n2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J20 compound treatment 0.358 0.0219 1.77 0.351 0.0119 1.08 2.0106 0.9719 2079752 MixCom1_000218 CCCN1CCC(CC1)N2CCC(CC2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J21 compound treatment 0.35 0.0139 1.12 0.348 0.00887 0.8 1.3625 0.9867 2079753 MixCom1_000219 COc1cc(OC)nc(n1)c2n[nH]c(=S)n2CC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J22 compound treatment 0.344 0.00793 0.64 0.347 0.00787 0.71 0.9567 0.9985 2079754 MixCom1_000220 CCCN1CCC(CC1)N2CCC(CC2)C(=O)NC3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J23 mock treatment 0.336 -6.67E-5 -0.01 0.339 -1.33E-4 -0.01 -0.0124 -0.9331 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 J24 positive control 0.091 -0.245 -19.73 0.09 -0.249 -22.61 -29.9449 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K01 compound treatment 0.342 0.00593 0.48 0.346 0.00687 0.62 0.7786 0.9914 2069400 MixCom1_000221 CCN(C(=S)Nc1cccc(c1)C(F)(F)F)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K02 compound treatment 0.339 0.00293 0.24 0.348 0.00887 0.8 0.7361 0.8776 2069401 MixCom1_000222 CC(C)c1ccccc1NC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K03 compound treatment 0.347 0.0109 0.88 0.354 0.0149 1.35 1.5768 0.9786 1266374 MixCom1_000223 O=C(N1CCN(CCOc2ccccc2)CC1)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K04 compound treatment 0.339 0.00293 0.24 0.35 0.0109 0.99 0.8645 0.8523 2069402 MixCom1_000224 CC(=O)Nc1ccc(Cl)cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K05 compound treatment 0.331 -0.00507 -0.41 0.341 0.00187 0.17 -0.1687 -0.3818 1159261 MixCom1_000225 O=C(Nc1ccc2ccccc2c1)N3CCCN(CCOc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K06 compound treatment 0.339 0.00293 0.24 0.344 0.00487 0.44 0.4794 0.957 2069403 MixCom1_000226 NC(=O)Cc1ccc(F)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K07 compound treatment 0.343 0.00693 0.56 0.358 0.0189 1.71 1.6057 0.8915 1700453 MixCom1_000227 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)Nc2ccc(F)cc2F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K08 compound treatment 0.37 0.0339 2.73 0.355 0.0159 1.44 2.9506 0.9552 2069404 MixCom1_000228 CN(C)/C=N/c1nnc(SCc2ccc(cc2)[N+](=O)[O-])s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K09 compound treatment 0.398 0.0619 4.99 0.35 0.0109 0.99 4.224 0.8309 1435466 MixCom1_000229 CN(CCOC(=O)c1ccc(Cl)cc1)c2nc3cc(Cl)ccc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K10 compound treatment 0.4 0.0639 5.15 0.35 0.0109 0.99 4.3379 0.8275 1088064 MixCom1_000230 CC1=C(C(=O)Nc2ccccc2)S(=O)(=O)CCO1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K11 compound treatment 0.403 0.0669 5.39 0.35 0.0109 0.99 4.5087 0.8228 1016457 MixCom1_000231 CC1(C)CCC(C)(C)c2cc3c(cc21)C(C)(C)CCC3(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K12 compound treatment 0.425 0.0889 7.16 0.362 0.0229 2.08 6.5316 0.876 2069405 MixCom1_000232 CC1=N/C(=C\c2cccc(c2)[N+](=O)[O-])/C(=O)O1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K13 compound treatment 0.412 0.0759 6.11 0.371 0.0319 2.89 6.3691 0.9416 2069406 MixCom1_000233 FC(F)(F)c1cccc(c1)C(=O)CC#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K14 compound treatment 0.367 0.0309 2.49 0.328 -0.0111 -1.01 1.0468 0.3894 1007168 MixCom1_000234 CN(C)Cc1c(O)ccc2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K15 compound treatment 0.381 0.0449 3.62 0.348 0.00887 0.8 3.1276 0.8438 2069407 MixCom1_000235 CC(=O)Nc1ccc(OC(F)(F)F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K16 compound treatment 0.373 0.0369 2.97 0.35 0.0109 0.99 2.8005 0.8938 1075367 MixCom1_000236 CC(C)(C)c1ccc(cc1)C(=O)C2CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K17 compound treatment 0.365 0.0289 2.33 0.355 0.0159 1.44 2.6659 0.9733 1063399 MixCom1_000237 CC(=O)Nc1ccc(cc1C(=O)O)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K18 compound treatment 0.354 0.0179 1.44 0.345 0.00587 0.53 1.3977 0.9081 1298979 MixCom1_000238 CCOC(=O)c1nc(sc1C(=O)OCC)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K19 compound treatment 0.348 0.0119 0.96 0.346 0.00687 0.62 1.1202 0.978 2069408 MixCom1_000239 CC(=O)Nc1ccc(C)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K20 compound treatment 0.343 0.00693 0.56 0.343 0.00387 0.35 0.643 0.975 2069409 MixCom1_000240 Clc1ccc(NC(=S)NCc2ccccc2)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K21 compound treatment 0.343 0.00693 0.56 0.35 0.0109 0.99 1.0923 0.9637 1777053 MixCom1_000241 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K22 compound treatment 0.344 0.00793 0.64 0.348 0.00887 0.8 1.0208 0.9935 2069410 MixCom1_000242 O/N=C\c1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K23 mock treatment 0.335 -0.00107 -0.09 0.338 -0.00113 -0.1 -0.1335 -0.996 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 K24 positive control 0.091 -0.245 -19.73 0.091 -0.248 -22.52 -29.8808 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L01 compound treatment 0.338 0.00193 0.16 0.342 0.00287 0.26 0.2941 0.9698 2079755 MixCom1_000243 CCCn1c(n[nH]c1=S)c2nc(OC)cc(OC)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L02 compound treatment 0.338 0.00193 0.16 0.349 0.00987 0.9 0.7434 0.8178 2079756 MixCom1_000244 CCCN1CCC(CC1)N2CCC(CC2)C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L03 compound treatment 0.347 0.0109 0.88 0.356 0.0169 1.53 1.7051 0.9655 2079757 MixCom1_000245 COc1cc(OC)nc(n1)c2n[nH]c(=S)n2c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L04 compound treatment 0.335 -0.00107 -0.09 0.344 0.00487 0.44 0.2516 0.5591 2079758 MixCom1_000246 CCCN1CCC(CC1)N2CCC(CC2)C(=O)NCc3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L05 compound treatment 0.36 0.0239 1.93 0.382 0.0429 3.89 4.1142 0.9475 2079759 MixCom1_000247 COc1cc(OC)nc(n1)c2n[nH]c(=S)n2c3ccc(cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L06 compound treatment 0.334 -0.00207 -0.17 0.334 -0.00513 -0.47 -0.4472 -0.9037 2079760 MixCom1_000248 CCCN1CCC(CC1)N2CCC(CC2)C(=O)NC(C)c3ccc(cc3)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L07 compound treatment 0.347 0.0109 0.88 0.347 0.00787 0.71 1.1275 0.9946 2079761 MixCom1_000249 O/C=C(\C=O)/c1cc(F)cc(F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L08 compound treatment 0.374 0.0379 3.05 0.337 -0.00213 -0.19 2.023 0.661 2079762 MixCom1_000250 CCCN1CCC(CC1)N2CCC(CC2)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L09 compound treatment 0.392 0.0559 4.5 0.353 0.0139 1.26 4.0749 0.8713 2079763 MixCom1_000251 Fc1cc(F)cc(c1)c2cn[nH]c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L10 compound treatment 0.395 0.0589 4.75 0.357 0.0179 1.62 4.5025 0.8978 2079764 MixCom1_000252 Fc1ccc(cc1)N2CCN(CC2)C3CCNCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L11 compound treatment 0.397 0.0609 4.91 0.356 0.0169 1.53 4.5522 0.8856 2079765 MixCom1_000253 Cn1cc(cn1)c2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L12 compound treatment 0.405 0.0689 5.55 0.355 0.0159 1.44 4.9435 0.862 1341399 MixCom1_000254 CC(=O)N1CCC(CC1)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L13 compound treatment 0.407 0.0709 5.71 0.356 0.0169 1.53 5.1216 0.8661 2079766 MixCom1_000255 OCCn1cc(cn1)c2cc(F)cc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L14 compound treatment 0.391 0.0549 4.42 0.352 0.0129 1.17 3.9538 0.8642 2079767 MixCom1_000256 OC(=O)/C=C\C(=O)N1CCC(CC1)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L15 compound treatment 0.378 0.0419 3.38 0.347 0.00787 0.71 2.8926 0.8381 2079768 MixCom1_000257 Fc1cc(F)cc(c1)c2cnn(c2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L16 compound treatment 0.376 0.0399 3.22 0.35 0.0109 0.99 2.9713 0.8834 2079769 MixCom1_000258 OC(=O)CCCC(=O)N1CCC(CC1)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L17 compound treatment 0.354 0.0179 1.44 0.356 0.0169 1.53 2.1037 0.9996 2079770 MixCom1_000259 OC(=O)c1cccc(c1)n2cc(cn2)c3cc(F)cc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L18 compound treatment 0.352 0.0159 1.28 0.351 0.0119 1.08 1.6689 0.9962 2079771 MixCom1_000260 OC(=O)COCC(=O)N1CCC(CC1)N2CCN(CC2)c3ccc(F)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L19 compound treatment 0.36 0.0239 1.93 0.356 0.0169 1.53 2.4454 0.9935 2079772 MixCom1_000261 OC(=O)c1ccc(cc1)n2cc(cn2)c3cc(F)cc(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L20 compound treatment 0.371 0.0349 2.81 0.361 0.0219 1.98 3.3926 0.9854 2079773 MixCom1_000262 Cc1ccccc1C(=O)N2CCC(CC2)N3CCN(CC3)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L21 compound treatment 0.336 -6.67E-5 -0.01 0.344 0.00487 0.44 0.3086 0.6985 2079774 MixCom1_000263 CCNC(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L22 compound treatment 0.369 0.0329 2.65 0.364 0.0249 2.26 3.4713 0.9968 2079775 MixCom1_000264 Fc1ccc(cc1)N2CCN(CC2)C3CCN(CC3)C(=O)c4cccc(c4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L23 mock treatment 0.34 0.00393 0.32 0.341 0.00187 0.17 0.3438 0.957 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 L24 positive control 0.093 -0.243 -19.57 0.092 -0.247 -22.43 -29.7027 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M01 compound treatment 0.339 0.00293 0.24 0.344 0.00487 0.44 0.4794 0.957 1430441 MixCom1_000265 CCN(C(=S)Nc1ccc(OC)cc1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M02 compound treatment 0.33 -0.00607 -0.49 0.337 -0.00213 -0.19 -0.4824 -0.9179 2069411 MixCom1_000266 CCCc1ccc(cc1)/C(=N/O)/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M03 compound treatment 0.356 0.0199 1.61 0.359 0.0199 1.8 2.4102 0.9983 1367521 MixCom1_000267 Clc1ccccc1c2cnoc2C(=O)N3CCN(CCOc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M04 compound treatment 0.312 -0.0241 -1.94 0.331 -0.00813 -0.74 -1.8924 -0.9125 2069412 MixCom1_000268 Cc1ccc(C(=O)c2cc(Cl)cc(Cl)c2)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M05 compound treatment 0.329 -0.00707 -0.57 0.339 -1.33E-4 -0.01 -0.4109 -0.722 1578471 MixCom1_000269 Fc1cccc(Cl)c1CN2CCC(CC2)NC(=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M06 compound treatment 0.328 -0.00807 -0.65 0.332 -0.00713 -0.65 -0.9172 -1.0 1489129 MixCom1_000270 Cc1sc(N)nc1c2ccc(C)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M07 compound treatment 0.353 0.0169 1.36 0.341 0.00187 0.17 1.084 0.7889 1286673 MixCom1_000271 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)Nc2ccc(F)c(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M08 compound treatment 0.381 0.0449 3.62 0.345 0.00587 0.53 2.9351 0.8025 2069413 MixCom1_000272 CCOC(=O)CSc1nnc(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M09 compound treatment 0.384 0.0479 3.86 0.351 0.0119 1.08 3.491 0.8711 2069414 MixCom1_000273 Cn1c(S)ncc1c2ccc(Cl)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M10 compound treatment 0.396 0.0599 4.83 0.344 0.00487 0.44 3.725 0.7686 2069415 MixCom1_000274 CC(=O)C1=C(C)OC(=C(C#N)C1c2ccco2)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M11 compound treatment 0.343 0.00693 0.56 0.311 -0.0281 -2.55 -1.411 -0.5398 2069416 MixCom1_000275 FC(F)(F)c1cccc(CSc2nnc(S)s2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M12 compound treatment 0.384 0.0479 3.86 0.34 8.67E-4 0.08 2.785 0.7214 1026284 MixCom1_000276 NC(c1ccccc1)c2c(O)ccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M13 compound treatment 0.411 0.0749 6.03 0.342 0.00287 0.26 4.4508 0.7369 2069417 MixCom1_000277 CC(=O)Nc1ccc(OC(F)(F)F)cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M14 compound treatment 0.369 0.0329 2.65 0.334 -0.00513 -0.47 1.5458 0.5741 1031546 MixCom1_000278 [O-][N+](=O)c1cccc(c1)C(OC(=O)c2ccccc2)C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M15 compound treatment 0.379 0.0429 3.46 0.345 0.00587 0.53 2.8212 0.8065 1002353 MixCom1_000279 CC(=O)Nc1ccccc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M16 compound treatment 0.361 0.0249 2.01 0.335 -0.00413 -0.38 1.1544 0.5652 2069418 MixCom1_000280 OC(C1CC1)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M17 compound treatment 0.344 0.00793 0.64 0.346 0.00687 0.62 0.8925 0.9999 2069419 MixCom1_000281 CC(=O)Nc1ccccc1OC(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M18 compound treatment 0.345 0.00893 0.72 0.346 0.00687 0.62 0.9494 0.9974 1666852 MixCom1_000282 OCc1cc(=O)c(O)c(CO)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M19 compound treatment 0.364 0.0279 2.25 0.366 0.0269 2.44 3.315 0.9992 2069420 MixCom1_000283 Brc1ccccc1NC(=O)Nc2ccccc2Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M20 compound treatment 0.328 -0.00807 -0.65 0.33 -0.00913 -0.83 -1.0455 -0.9927 2069421 MixCom1_000284 Brc1ccc(NC(=S)NCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M21 compound treatment 0.338 0.00193 0.16 0.344 0.00487 0.44 0.4225 0.9019 1027080 MixCom1_000285 Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M22 compound treatment 0.342 0.00593 0.48 0.343 0.00387 0.35 0.586 0.9885 1026358 MixCom1_000286 CCCC(CC(=O)O)(C(=O)O)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M23 mock treatment 0.332 -0.00407 -0.33 0.335 -0.00413 -0.38 -0.4969 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 M24 positive control 0.092 -0.244 -19.65 0.092 -0.247 -22.43 -29.7596 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N01 compound treatment 0.34 0.00393 0.32 0.345 0.00587 0.53 0.6005 0.9692 2079776 MixCom1_000287 CC(C)(C)C(=O)N(C1CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N02 compound treatment 0.341 0.00493 0.4 0.348 0.00887 0.8 0.85 0.947 2079777 MixCom1_000288 Fc1ccc(cc1)N2CCN(CC2)C3CCN(CC3)S(=O)(=O)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N03 compound treatment 0.321 -0.0151 -1.21 0.33 -0.00913 -0.83 -1.4441 -0.9828 2079778 MixCom1_000289 O=C(N(C1CC1)C2CCN(CCc3ccccc3)CC2)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N04 compound treatment 0.337 9.33E-4 0.08 0.347 0.00787 0.71 0.5581 0.7772 2079779 MixCom1_000290 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)N3CCN(CC3)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N05 compound treatment 0.314 -0.0221 -1.78 0.326 -0.0131 -1.19 -2.0995 -0.9811 2079780 MixCom1_000291 O=C(/C=C/c1ccccc1)N(C2CC2)C3CCN(CCc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N06 compound treatment 0.351 0.0149 1.2 0.348 0.00887 0.8 1.4194 0.9809 2079781 MixCom1_000292 OC(=O)C1CCCN(C1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N07 compound treatment 0.347 0.0109 0.88 0.33 -0.00913 -0.83 0.0363 0.03 2079782 MixCom1_000293 O=S(=O)(N(C1CC1)C2CCN(CCc3ccccc3)CC2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N08 compound treatment 0.391 0.0549 4.42 0.354 0.0149 1.35 4.0822 0.8827 2079783 MixCom1_000294 CNC(=O)C1CCCN(C1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N09 compound treatment 0.359 0.0229 1.85 0.324 -0.0151 -1.37 0.3345 0.1453 2079784 MixCom1_000295 Cc1cc(C)cc(NC(=O)N(C2CC2)C3CCN(CCc4ccccc4)CC3)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N10 compound treatment 0.428 0.0919 7.4 0.367 0.0279 2.53 7.0234 0.8978 2079785 MixCom1_000296 FC(F)(F)c1ccc(nc1)N2CCCC(C2)C(=O)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N11 compound treatment 0.297 -0.0391 -3.15 0.274 -0.0651 -5.91 -6.4051 -0.9564 2079786 MixCom1_000297 FC(F)(F)c1cccc(c1)C(=O)N(C2CC2)C3CCN(CCc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N12 compound treatment 0.419 0.0829 6.68 0.361 0.0219 1.98 6.1258 0.8793 2079787 MixCom1_000298 FC(F)(F)c1ccc(nc1)N2CCCC(C2)C(=O)NCc3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N13 compound treatment 0.387 0.0509 4.1 0.346 0.00687 0.62 3.3409 0.8053 2079788 MixCom1_000299 Clc1ccc(cc1)S(=O)(=O)N(C2CC2)C3CCN(CCc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N14 compound treatment 0.411 0.0749 6.03 0.372 0.0329 2.98 6.3763 0.9473 2079789 MixCom1_000300 COC(=O)C1CCN(CC1)C(=O)C2CCCN(C2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N15 compound treatment 0.356 0.0199 1.61 0.331 -0.00813 -0.74 0.613 0.3469 2079790 MixCom1_000301 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(C2CC2)C3CCN(CCc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N16 compound treatment 0.374 0.0379 3.05 0.346 0.00687 0.62 2.6007 0.8342 2079791 MixCom1_000302 CCCCCCCCCCCCNC(=O)C1CCCN(C1)c2ccc(cn2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N17 compound treatment 0.35 0.0139 1.12 0.341 0.00187 0.17 0.9132 0.8048 2079792 MixCom1_000303 Fc1cc(F)cc(c1)c2cnoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N18 compound treatment 0.344 0.00793 0.64 0.351 0.0119 1.08 1.2134 0.9689 2079793 MixCom1_000304 CN1CCC(CC1)N2CCCC(C2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N19 compound treatment 0.336 -6.67E-5 -0.01 0.344 0.00487 0.44 0.3086 0.6985 2079794 MixCom1_000305 Clc1ccc(cc1)c2cnoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N20 compound treatment 0.344 0.00793 0.64 0.351 0.0119 1.08 1.2134 0.9689 2079795 MixCom1_000306 CCCN1CCC(CC1)N2CCCC(C2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N21 compound treatment 0.351 0.0149 1.2 0.351 0.0119 1.08 1.612 0.9985 2079796 MixCom1_000307 c1nocc1c2nc3ccccc3o2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N22 compound treatment 0.341 0.00493 0.4 0.347 0.00787 0.71 0.7858 0.9617 2079797 MixCom1_000308 CN1CCC(CC1)N2CCCC(C2)C(=O)NC3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N23 mock treatment 0.338 0.00193 0.16 0.338 -0.00113 -0.1 0.0373 0.2001 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 N24 positive control 0.09 -0.246 -19.81 0.091 -0.248 -22.52 -29.9377 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O01 compound treatment 0.35 0.0139 1.12 0.354 0.0149 1.35 1.7476 0.9958 2069422 MixCom1_000309 CCN(C(=S)Nc1c(C)cccc1C)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O02 compound treatment 0.363 0.0269 2.17 0.369 0.0299 2.71 3.4506 0.9939 2069423 MixCom1_000310 CCCc1ccc(NC(=O)C)c(c1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O03 compound treatment 0.365 0.0289 2.33 0.367 0.0279 2.53 3.4361 0.9992 1211065 MixCom1_000311 Clc1ccc(cc1)C(=O)N2CCN(CCOc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O04 compound treatment 0.345 0.00893 0.72 0.351 0.0119 1.08 1.2703 0.9807 1281850 MixCom1_000312 CC(=O)NCc1cccnc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O05 compound treatment 0.344 0.00793 0.64 0.346 0.00687 0.62 0.8925 0.9999 1140212 MixCom1_000313 Fc1cccc(Cl)c1CN2CCC(CC2)NC(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O06 compound treatment 0.34 0.00393 0.32 0.341 0.00187 0.17 0.3438 0.957 2069424 MixCom1_000314 C/C(=N\Cc1ccccc1)/c2ccccc2O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O07 compound treatment 0.336 -6.67E-5 -0.01 0.352 0.0129 1.17 0.8221 0.7038 1181278 MixCom1_000315 CCCCc1ccc(NC(=O)N2CCC(CC2)NC(=O)OC(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O08 compound treatment 0.346 0.00993 0.8 0.341 0.00187 0.17 0.6854 0.8383 2069425 MixCom1_000316 CCCCCCSc1nnc(N)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O09 compound treatment 0.358 0.0219 1.77 0.354 0.0149 1.35 2.2031 0.9912 1716032 MixCom1_000317 NC(=O)C(C(=O)N)c1ccccc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O10 compound treatment 0.349 0.0129 1.04 0.348 0.00887 0.8 1.3055 0.9919 2069426 MixCom1_000318 O=C1CC(C=C1Nc2ccccc2)N3CCN(CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O11 compound treatment 0.351 0.0149 1.2 0.354 0.0149 1.35 1.8045 0.9983 1554557 MixCom1_000319 Nc1nc(=N)nc(S)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O12 compound treatment 0.349 0.0129 1.04 0.358 0.0189 1.71 1.9474 0.9716 1170762 MixCom1_000320 CCC(CC)(c1cc(C)c(O)c(C)c1)c2cc(C)c(O)c(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O13 compound treatment 0.347 0.0109 0.88 0.352 0.0129 1.17 1.4484 0.9903 2069427 MixCom1_000321 FC(F)(F)Oc1ccccc1NCN2C(=O)CCC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O14 compound treatment 0.346 0.00993 0.8 0.355 0.0159 1.44 1.584 0.9615 2069428 MixCom1_000322 CC(C(Nc1ccccc1)c2ccccc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O15 compound treatment 0.349 0.0129 1.04 0.35 0.0109 0.99 1.4339 0.9996 2069429 MixCom1_000323 COC(=O)Nc1cc(Cl)cc(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O16 compound treatment 0.348 0.0119 0.96 0.353 0.0139 1.26 1.5695 0.9911 1257530 MixCom1_000324 OCC(O)COc1ccc(Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O17 compound treatment 0.349 0.0129 1.04 0.353 0.0139 1.26 1.6265 0.9956 1053294 MixCom1_000325 O=C(CC#N)N1CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O18 compound treatment 0.348 0.0119 0.96 0.347 0.00787 0.71 1.1844 0.9893 1083221 MixCom1_000326 Cc1cc(C)cc(OCCC#N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O19 compound treatment 0.342 0.00593 0.48 0.347 0.00787 0.71 0.8428 0.9809 2069430 MixCom1_000327 CCOC(=O)c1c[nH]c2c(OC(F)(F)F)cccc2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O20 compound treatment 0.336 -6.67E-5 -0.01 0.34 8.67E-4 0.08 0.0518 0.6573 1136526 MixCom1_000328 CCC(=O)Oc1c(C)cc(O)c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O21 compound treatment 0.353 0.0169 1.36 0.35 0.0109 0.99 1.6617 0.9874 1026723 MixCom1_000329 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O22 compound treatment 0.35 0.0139 1.12 0.355 0.0159 1.44 1.8118 0.9924 1416824 MixCom1_000330 O=c1cc(c2ccccc2)c3ccccc3[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O23 mock treatment 0.348 0.0119 0.96 0.34 8.67E-4 0.08 0.7351 0.7624 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 O24 positive control 0.092 -0.244 -19.65 0.092 -0.247 -22.43 -29.7596 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P01 compound treatment 0.344 0.00793 0.64 0.347 0.00787 0.71 0.9567 0.9985 2079798 MixCom1_000331 c1nc(co1)c2ccnc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P02 compound treatment 0.338 0.00193 0.16 0.344 0.00487 0.44 0.4225 0.9019 2079799 MixCom1_000332 OC(=O)C1CCN(CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P03 compound treatment 0.336 -6.67E-5 -0.01 0.353 0.0139 1.26 0.8862 0.7041 2079800 MixCom1_000333 c1nocc1c2ccc(cc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P04 compound treatment 0.334 -0.00207 -0.17 0.343 0.00387 0.35 0.1305 0.336 2079801 MixCom1_000334 OC(=O)C1CCCN(C1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P05 compound treatment 0.337 9.33E-4 0.08 0.337 -0.00213 -0.19 -0.0838 -0.4033 2079802 MixCom1_000335 OC(=O)C1CCN(CC1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P06 compound treatment 0.336 -6.67E-5 -0.01 0.338 -0.00113 -0.1 -0.0765 -0.743 2079803 MixCom1_000336 CCNC(=O)C1CCCN(C1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P07 compound treatment 0.331 -0.00507 -0.41 0.343 0.00387 0.35 -0.0403 -0.0749 2079804 MixCom1_000337 CC(C)NC(=O)C1CCN(CC1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P08 compound treatment 0.334 -0.00207 -0.17 0.339 -1.33E-4 -0.01 -0.1262 -0.7565 2079805 MixCom1_000338 O=C(C1CCCN(C1)C2CCN(CCc3ccccc3)CC2)N4CCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P09 compound treatment 0.333 -0.00307 -0.25 0.335 -0.00413 -0.38 -0.4399 -0.9794 2079806 MixCom1_000339 O=C(NCCc1ccccc1)C2CCN(CC2)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P10 compound treatment 0.335 -0.00107 -0.09 0.334 -0.00513 -0.47 -0.3902 -0.8236 2079807 MixCom1_000340 CCCCNC(=O)C1CCN(CC1)C2CCN(CCc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P11 compound treatment 0.33 -0.00607 -0.49 0.329 -0.0101 -0.92 -0.9958 -0.9562 2079808 MixCom1_000341 COc1ccccc1CNC(=O)C2CCN(CC2)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P12 compound treatment 0.332 -0.00407 -0.33 0.336 -0.00313 -0.28 -0.4327 -0.9975 2079809 MixCom1_000342 CCCCCCCCCCCCNC(=O)C1CCCN(C1)C2CCN(CCC)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P13 compound treatment 0.339 0.00293 0.24 0.341 0.00187 0.17 0.2868 0.9867 2079810 MixCom1_000343 CN1CCC(CC1)N(C2CC2)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P14 compound treatment 0.342 0.00593 0.48 0.341 0.00187 0.17 0.4577 0.9028 2079811 MixCom1_000344 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P15 compound treatment 0.336 -6.67E-5 -0.01 0.343 0.00387 0.35 0.2444 0.6962 2079812 MixCom1_000345 CN1CCC(CC1)N(C2CC2)C(=O)CCCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P16 compound treatment 0.348 0.0119 0.96 0.346 0.00687 0.62 1.1202 0.978 2079813 MixCom1_000346 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)N(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P17 compound treatment 0.339 0.00293 0.24 0.342 0.00287 0.26 0.351 0.9988 2079814 MixCom1_000347 CN1CCC(CC1)N(C2CC2)C(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P18 compound treatment 0.338 0.00193 0.16 0.346 0.00687 0.62 0.5508 0.8574 2079815 MixCom1_000348 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)NC3CCCCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P19 compound treatment 0.338 0.00193 0.16 0.342 0.00287 0.26 0.2941 0.9698 2079816 MixCom1_000349 CCCN1CCC(CC1)N(C2CC2)C(=O)/C=C\C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P20 compound treatment 0.344 0.00793 0.64 0.347 0.00787 0.71 0.9567 0.9985 2079817 MixCom1_000350 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)NCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P21 compound treatment 0.341 0.00493 0.4 0.347 0.00787 0.71 0.7858 0.9617 2079818 MixCom1_000351 CC(=O)N1CCC(CC1)N(C2CC2)C(=O)CCCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P22 compound treatment 0.344 0.00793 0.64 0.346 0.00687 0.62 0.8925 0.9999 2079819 MixCom1_000352 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)NCc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P23 mock treatment 0.332 -0.00407 -0.33 0.334 -0.00513 -0.47 -0.561 -0.9851 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.541 P24 positive control 0.093 -0.243 -19.57 0.093 -0.246 -22.34 -29.6385 -0.9978 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A01 mock treatment 0.307 -0.0253 -2.04 0.307 -0.0146 -1.33 -2.3763 -0.9784 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A02 mock treatment 0.311 -0.0213 -1.71 0.314 -0.0076 -0.69 -1.6993 -0.92 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A03 compound treatment 0.324 -0.00828 -0.67 0.314 -0.0076 -0.69 -0.959 -0.9999 1907783 MixCom2_000001 ClC1=C(N2CCC(CC2)C(=O)N3CCOCC3)C(=O)c4ccccc4C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A04 compound treatment 0.328 -0.00428 -0.34 0.333 0.0114 1.03 0.4882 0.4477 1970020 MixCom2_000002 CC(CCOC(=O)NNC(=O)c1snnc1c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A05 compound treatment 0.316 -0.0163 -1.31 0.311 -0.0106 -0.96 -1.6071 -0.9885 1907784 MixCom2_000003 COC(=O)CC(NS(=O)(=O)c1cccs1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A06 compound treatment 0.312 -0.0203 -1.63 0.312 -0.0096 -0.87 -1.7707 -0.9568 1970021 MixCom2_000004 Cn1cccc1C(=O)NNC(=O)OCCc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A07 compound treatment 0.315 -0.0173 -1.39 0.312 -0.0096 -0.87 -1.5999 -0.9746 1907785 MixCom2_000005 COc1ccc(cc1)C(CC(=O)N2CCN(C)CC2)NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A08 compound treatment 0.31 -0.0223 -1.79 0.304 -0.0176 -1.6 -2.3981 -0.9983 1970022 MixCom2_000006 CN1CCCC1CCOC(=O)NNC(=O)c2sc(nc2C)c3ccc(cc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A09 compound treatment 0.305 -0.0273 -2.2 0.306 -0.0156 -1.42 -2.5544 -0.9775 1907786 MixCom2_000007 COC(=O)CC(NC(=O)c1cccc(Cl)c1)c2cccc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A10 compound treatment 0.309 -0.0233 -1.87 0.304 -0.0176 -1.6 -2.455 -0.9968 1970023 MixCom2_000008 Cc1cccc(CCOC(=O)NNC(=O)c2ccc(F)cc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A11 compound treatment 0.313 -0.0193 -1.55 0.311 -0.0106 -0.96 -1.7779 -0.9736 1907787 MixCom2_000009 COc1ccc(cc1)C(CC(=O)N2CCCCC2)NC(=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A12 compound treatment 0.332 -2.76E-4 -0.02 0.315 -0.0066 -0.6 -0.4393 -0.7328 1970024 MixCom2_000010 COc1ccc(cc1)N2CCN(CC2C)C(=O)OCCN3CCN(Cc4cc5OCOc5c(OC)c4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A13 compound treatment 0.314 -0.0183 -1.47 0.31 -0.0116 -1.05 -1.7852 -0.9865 1907788 MixCom2_000011 CNC(=S)NNC(=O)c1csc(n1)n2nc(C)cc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A14 compound treatment 0.323 -0.00928 -0.75 0.317 -0.0046 -0.42 -0.8234 -0.9622 1970025 MixCom2_000012 CC(C)(C)OC(=O)N(CCOC(=O)NC1CCN(Cc2ccccc2)C1)Cc3cc4ccccc4c5ccccc35 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A15 compound treatment 0.359 0.0267 2.15 0.345 0.0234 2.12 3.0236 1.0 1907789 MixCom2_000013 Cc1cc(n(n1)c2nc(cs2)C(=O)N/N=C/c3cccnc3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A16 compound treatment 0.327 -0.00528 -0.42 0.321 -6.0E-4 -0.05 -0.3389 -0.7913 1970026 MixCom2_000014 [O-][N+](=O)c1ccc(NCCNC(=O)OCc2nc(cs2)c3ccc(Cl)cc3)nc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A17 compound treatment 0.318 -0.0143 -1.15 0.315 -0.0066 -0.6 -1.2365 -0.9539 1907790 MixCom2_000015 CCNC(=S)NNC(=O)c1csc(n1)n2nc(C)cc2C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A18 compound treatment 0.299 -0.0333 -2.68 0.298 -0.0236 -2.14 -3.4095 -0.9938 1970027 MixCom2_000016 Cc1ccc(CCOC(=O)NNC(=O)c2csc(n2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A19 compound treatment 0.317 -0.0153 -1.23 0.31 -0.0116 -1.05 -1.6144 -0.997 1459959 MixCom2_000017 Fc1cccc(COc2cc(NC(=O)C3CC3)c(Cl)cc2Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A20 compound treatment 0.317 -0.0153 -1.23 0.31 -0.0116 -1.05 -1.6144 -0.997 1970028 MixCom2_000018 Cc1cc(C)c(CCOC(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)c(C)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A21 compound treatment 0.313 -0.0193 -1.55 0.309 -0.0126 -1.14 -1.9063 -0.9887 1907791 MixCom2_000019 Cc1ccc(cc1)C(=O)c2c[nH]c(c2)C(=O)NCCCN3CCOCC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A22 compound treatment 0.311 -0.0213 -1.71 0.306 -0.0156 -1.42 -2.2128 -0.9955 1970029 MixCom2_000020 COc1cc(Br)c(CN2CCN(CC2)C(=O)OCC3CC4CC3C=C4)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A23 positive control 0.079 -0.253 -20.4 0.081 -0.241 -21.84 -29.8647 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 A24 positive control 0.081 -0.251 -20.23 0.081 -0.241 -21.84 -29.7508 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B01 mock treatment 0.327 -0.00528 -0.42 0.324 0.0024 0.22 -0.1464 -0.3066 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B02 mock treatment 0.334 0.00172 0.14 0.328 0.0064 0.58 0.509 0.8521 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B03 compound treatment 0.339 0.00672 0.54 0.334 0.0124 1.13 1.1788 0.9437 1970030 MixCom2_000021 COCc1nc2ccc(Br)cc2c3C(=O)N(CCCN4CCCC4=O)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B04 compound treatment 0.343 0.0107 0.86 0.338 0.0164 1.49 1.6633 0.9665 1970031 MixCom2_000022 O=C(N1CCN(CC1)c2ccccc2)c3ccc(s3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B05 compound treatment 0.333 7.24E-4 0.06 0.315 -0.0066 -0.6 -0.3824 -0.6353 1970032 MixCom2_000023 Cc1ccc(s1)C(=O)NN2C(=O)c3c(C2=O)c4cc(Cl)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B06 compound treatment 0.341 0.00872 0.7 0.334 0.0124 1.13 1.2927 0.9743 1970033 MixCom2_000024 Cc1nc(cn1CCC(=O)N2CCN(C/C=C/c3ccccc3)CC2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B07 compound treatment 0.331 -0.00128 -0.1 0.328 0.0064 0.58 0.3381 0.5732 1970034 MixCom2_000025 CCN(CC)c1ccc(cc1)C(=O)NN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B08 compound treatment 0.341 0.00872 0.7 0.333 0.0114 1.03 1.2285 0.9822 1970035 MixCom2_000026 CN(C)c1ccc(CNC(=O)c2cc(=O)n([nH]2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B09 compound treatment 0.34 0.00772 0.62 0.333 0.0114 1.03 1.1715 0.9703 1970036 MixCom2_000027 COCc1nc2ccccc2c3C(=O)N(CCC4CCCN4C)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B10 compound treatment 0.319 -0.0133 -1.07 0.317 -0.0046 -0.42 -1.0512 -0.9159 1970037 MixCom2_000028 NC(=O)C(Cc1ccc(O)cc1)NC(=O)CCC(=O)Nc2ccc(Br)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B11 compound treatment 0.343 0.0107 0.86 0.34 0.0184 1.67 1.7916 0.9529 1970038 MixCom2_000029 COCC(Cc1ccccc1)N2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B12 compound treatment 0.352 0.0197 1.59 0.344 0.0224 2.03 2.5609 0.9925 1970039 MixCom2_000030 FC(F)(F)c1cccc(c1)C(=O)NNC(=O)c2ccc3nsnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B13 compound treatment 0.343 0.0107 0.86 0.334 0.0124 1.13 1.4065 0.9914 1970040 MixCom2_000031 O=C1N(C2CCCCNC2=O)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B14 compound treatment 0.346 0.0137 1.11 0.331 0.0094 0.85 1.3848 0.9918 1970041 MixCom2_000032 COC(=O)CCCCC(=O)NNC(=O)c1ccco1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B15 compound treatment 0.343 0.0107 0.86 0.336 0.0144 1.31 1.5349 0.9798 1970042 MixCom2_000033 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)CC4(CC5CC6CC(C5)C4)C6)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B16 compound treatment 0.342 0.00972 0.78 0.335 0.0134 1.22 1.4138 0.9773 1970043 MixCom2_000034 COc1cc(CCNC(=O)c2cc(C)n(C)n2)cc(OC)c1O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B17 compound treatment 0.338 0.00572 0.46 0.325 0.0034 0.31 0.5442 0.981 1970044 MixCom2_000035 Clc1cc2OCOc2cc1CN3CCC(C3)N4C(=O)c5ccccc5C4=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B18 compound treatment 0.342 0.00972 0.78 0.337 0.0154 1.4 1.5422 0.9625 1970045 MixCom2_000036 COC(=O)CCCC(=O)NNC(=O)c1sc(SC)c2c1CCCC32SCCS3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B19 compound treatment 0.345 0.0127 1.02 0.341 0.0194 1.76 1.9697 0.9668 1970046 MixCom2_000037 CC(C)c1nc2ccc(F)cc2c3C(=O)N(Cc4nc5ccccc5[nH]4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B20 compound treatment 0.338 0.00572 0.46 0.337 0.0154 1.4 1.3144 0.893 1970047 MixCom2_000038 CCN(CCNC(=O)CCC(=O)c1ccccc1)c2cccc(C)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B21 compound treatment 0.342 0.00972 0.78 0.337 0.0154 1.4 1.5422 0.9625 1970048 MixCom2_000039 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)c4ccc5OCOc5c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B22 compound treatment 0.338 0.00572 0.46 0.331 0.0094 0.85 0.9293 0.9582 1970049 MixCom2_000040 CCN1CC(CN1CC)NC(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B23 positive control 0.082 -0.25 -20.15 0.081 -0.241 -21.84 -29.6938 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 B24 positive control 0.082 -0.25 -20.15 0.082 -0.24 -21.75 -29.6297 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C01 mock treatment 0.324 -0.00828 -0.67 0.32 -0.0016 -0.15 -0.5739 -0.8415 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C02 mock treatment 0.33 -0.00228 -0.18 0.327 0.0054 0.49 0.217 0.4147 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C03 compound treatment 0.354 0.0217 1.75 0.35 0.0284 2.58 3.0598 0.9822 1700977 MixCom2_000041 CC(C)(C)C(=O)n1cc(CCN2CCS(=O)(=O)CC2)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C04 compound treatment 0.36 0.0277 2.23 0.354 0.0324 2.94 3.6582 0.9908 1970050 MixCom2_000042 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)OCCCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C05 compound treatment 0.34 0.00772 0.62 0.331 0.0094 0.85 1.0432 0.9879 1907792 MixCom2_000043 Fc1ccc(cc1)c2ccnn2c3nc(cs3)c4ccc(Br)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C06 compound treatment 0.339 0.00672 0.54 0.322 4.0E-4 0.04 0.4086 0.7528 1970051 MixCom2_000044 COc1ccccc1CCOC(=O)NCCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C07 compound treatment 0.333 7.24E-4 0.06 0.332 0.0104 0.94 0.7088 0.7494 1907793 MixCom2_000045 Cc1ccc(C)n1c2ccsc2c3cc4nccc(c5ccc(C)cc5)n4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C08 compound treatment 0.343 0.0107 0.86 0.331 0.0094 0.85 1.214 1.0 1970052 MixCom2_000046 O=C(Cc1csc(n1)c2ccccc2)NNC(=O)OCc3cccc(Oc4ccccc4)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C09 compound treatment 0.327 -0.00528 -0.42 0.324 0.0024 0.22 -0.1464 -0.3066 1907794 MixCom2_000047 CC(C)CC(=O)c1c[nH]c(c1)C(=O)NCc2cccc(c2)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C10 compound treatment 0.37 0.0377 3.04 0.366 0.0444 4.03 4.9979 0.9903 1970053 MixCom2_000048 OC1CCCN(C1)C(=O)OCCc2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C11 compound treatment 0.329 -0.00328 -0.26 0.315 -0.0066 -0.6 -0.6102 -0.9321 1907795 MixCom2_000049 COc1ccc(cc1)C(=O)c2c[nH]c(c2)C(=O)NCCCn3ccnc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C12 compound treatment 0.346 0.0137 1.11 0.338 0.0164 1.49 1.8341 0.9892 1970054 MixCom2_000050 CCN(Cc1ccncc1)C(=O)C(COC(=O)N2CCN(CC2)c3sc(cc3[N+](=O)[O-])S(=O)(=O)N)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C13 compound treatment 0.339 0.00672 0.54 0.33 0.0084 0.76 0.922 0.9859 1562281 MixCom2_000051 CC(C)CC(=O)c1c[nH]c(c1)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C14 compound treatment 0.33 -0.00228 -0.18 0.321 -6.0E-4 -0.05 -0.1681 -0.8792 1970055 MixCom2_000052 CC1CC1COC(=O)NNC(=O)CC2Sc3ccccc3NC2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C15 compound treatment 0.432 0.0997 8.03 0.418 0.0964 8.75 11.8658 0.9991 1525424 MixCom2_000053 COc1ccc(CNC(=O)c2cc(c[nH]2)C(=O)c3ccc(OC)cc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C16 compound treatment 0.337 0.00472 0.38 0.327 0.0054 0.49 0.6156 0.9921 1970056 MixCom2_000054 CC(C)(C)c1cc([nH]n1)C(=O)NNC(=O)OCCN2CCN(Cc3cc4ccccc4o3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C17 compound treatment 0.347 0.0147 1.19 0.337 0.0154 1.4 1.8269 0.9966 1467365 MixCom2_000055 CN(CCOc1ccc(cc1)c2ccn(n2)c3ncccn3)c4ccccn4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C18 compound treatment 0.333 7.24E-4 0.06 0.323 0.0014 0.13 0.1311 0.9376 1970057 MixCom2_000056 CC(CCOC(=O)NCc1ccc(Cl)cc1Cl)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C19 compound treatment 0.336 0.00372 0.3 0.332 0.0104 0.94 0.8796 0.888 1907796 MixCom2_000057 CCOC(=O)c1cnn(c2nc(cs2)c3ccc(C)cc3)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C20 compound treatment 0.342 0.00972 0.78 0.341 0.0194 1.76 1.7989 0.9334 1970058 MixCom2_000058 CC(CNC(=O)OCC#Cc1ccccc1)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C21 compound treatment 0.362 0.0297 2.39 0.361 0.0394 3.58 4.2214 0.9809 1907797 MixCom2_000059 CCOC(=O)c1cnn(c2nc(cs2)c3ccc(F)cc3)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C22 compound treatment 0.329 -0.00328 -0.26 0.328 0.0064 0.58 0.2243 0.3515 1970059 MixCom2_000060 Fc1ccc(COC(=O)N2CCN(CC2)c3ccccc3Cl)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C23 positive control 0.08 -0.252 -20.31 0.079 -0.243 -22.02 -29.9361 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 C24 positive control 0.083 -0.249 -20.07 0.082 -0.24 -21.75 -29.5727 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D01 mock treatment 0.333 7.24E-4 0.06 0.32 -0.0016 -0.15 -0.0615 -0.3927 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D02 mock treatment 0.339 0.00672 0.54 0.324 0.0024 0.22 0.5369 0.9199 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D03 compound treatment 0.341 0.00872 0.7 0.337 0.0154 1.4 1.4852 0.9493 1970060 MixCom2_000061 COCc1nc2ccc(Br)cc2c3C(=O)N(CC4(O)CCCCC4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D04 compound treatment 0.33 -0.00228 -0.18 0.318 -0.0036 -0.33 -0.3607 -0.9626 1970061 MixCom2_000062 O=C(CCC(=O)c1ccccc1)NC2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D05 compound treatment 0.365 0.0327 2.64 0.371 0.0494 4.48 5.0341 0.9679 1970062 MixCom2_000063 Cc1nc2ccc(Cl)cc2c3C(=O)N(Cc4ccccc4OC(F)(F)F)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D06 compound treatment 0.337 0.00472 0.38 0.337 0.0154 1.4 1.2574 0.868 1970063 MixCom2_000064 CCn1c2ccccc2c3cc(CN4CCN(CC4)C(=O)c5cccnc5Oc6ccc(C)cc6)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D07 compound treatment 0.361 0.0287 2.31 0.334 0.0124 1.13 2.4315 0.9452 1970064 MixCom2_000065 CCN(CCN1C(=O)c2c(C1=O)c3cc(C)ccc3nc2C)c4cccc(C)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D08 compound treatment 0.346 0.0137 1.11 0.337 0.0154 1.4 1.7699 0.9932 1970065 MixCom2_000066 CC(=O)N1CCN(CC1)C(=O)CCC(=O)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D09 compound treatment 0.344 0.0117 0.94 0.333 0.0114 1.03 1.3993 0.999 1970066 MixCom2_000067 COCc1nc2ccccc2c3C(=O)N(NC(=O)C4(CCC4)c5ccc(Cl)cc5)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D10 compound treatment 0.328 -0.00428 -0.34 0.325 0.0034 0.31 -0.0252 -0.0546 1970067 MixCom2_000068 CSc1ncc(C(=O)NNC(=O)OCc2ccc(F)cc2Cl)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D11 compound treatment 0.319 -0.0133 -1.07 0.315 -0.0066 -0.6 -1.1796 -0.9625 1970068 MixCom2_000069 Cc1ccc2nc(C)c3C(=O)N(NC(=O)c4ccccc4Cl)C(=O)c3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D12 compound treatment 0.331 -0.00128 -0.1 0.32 -0.0016 -0.15 -0.1753 -0.9856 1970069 MixCom2_000070 COc1cc(OC)c(CN2CCC(C2)NC(=O)c3ccc(cc3)n4nc(cc4C(C)(C)C)C(C)(C)C)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D13 compound treatment 0.345 0.0127 1.02 0.331 0.0094 0.85 1.3279 0.9959 1970070 MixCom2_000071 CN(C)c1ccc(cc1)C(=O)NN2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D14 compound treatment 0.34 0.00772 0.62 0.335 0.0134 1.22 1.2999 0.9515 1970071 MixCom2_000072 CC(C)(C)OC(=O)NC(CC1CCCCC1)C(=O)NNC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D15 compound treatment 0.332 -2.76E-4 -0.02 0.329 0.0074 0.67 0.4593 0.6833 1970072 MixCom2_000073 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)c4cc(n[nH]4)C(C)(C)C)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D16 compound treatment 0.328 -0.00428 -0.34 0.319 -0.0026 -0.24 -0.4104 -0.983 1970073 MixCom2_000074 Cn1c(CCC(=O)NNC(=O)Cc2ccsc2)nc3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D17 compound treatment 0.343 0.0107 0.86 0.38 0.0584 5.3 4.3591 0.8116 1970074 MixCom2_000075 COc1cc(nc2ccccc12)C(=O)NN3C(=O)c4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D18 compound treatment 0.322 -0.0103 -0.83 0.323 0.0014 0.13 -0.4953 -0.5916 1970075 MixCom2_000076 Clc1ccc(cc1)S(=O)(=O)N(CCC(=O)NNC(=O)c2ccccc2c3ccccc3)Cc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D19 compound treatment 0.336 0.00372 0.3 0.334 0.0124 1.13 1.008 0.8653 1970076 MixCom2_000077 CC(C)c1nc2ccc(F)cc2c3C(=O)N(Cc4ccccc4OC(F)(F)F)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D20 compound treatment 0.347 0.0147 1.19 0.336 0.0144 1.31 1.7627 0.9988 1970077 MixCom2_000078 CC(C)(C)OC(=O)NC(CCCCNC(=O)c1cccnc1)C(=O)NNC(=O)C(Cc2c[nH]cn2)NC(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D21 compound treatment 0.347 0.0147 1.19 0.348 0.0264 2.4 2.5329 0.9474 1970078 MixCom2_000079 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)C(=O)N4CCCc5ccccc45)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D22 compound treatment 0.339 0.00672 0.54 0.332 0.0104 0.94 1.0504 0.9652 1970079 MixCom2_000080 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=O)CCc3c[nH]c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D23 positive control 0.082 -0.25 -20.15 0.084 -0.238 -21.57 -29.5013 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 D24 positive control 0.084 -0.248 -19.99 0.085 -0.237 -21.48 -29.3232 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E01 mock treatment 0.328 -0.00428 -0.34 0.316 -0.0056 -0.51 -0.6029 -0.982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E02 mock treatment 0.33 -0.00228 -0.18 0.324 0.0024 0.22 0.0245 0.0859 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E03 compound treatment 0.341 0.00872 0.7 0.332 0.0104 0.94 1.1643 0.9894 1907798 MixCom2_000081 FC(F)(F)c1cc(nc2cc(nn12)c3ccc(Cl)c(Cl)c3)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E04 compound treatment 0.346 0.0137 1.11 0.338 0.0164 1.49 1.8341 0.9892 1970080 MixCom2_000082 COc1ccc(CCCOC(=O)NNC(=O)C2CN(C)CCN2C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E05 compound treatment 0.344 0.0117 0.94 0.33 0.0084 0.76 1.2067 0.9944 1907799 MixCom2_000083 Cc1onc(c1C(=O)N2CCN=C(C=C2)C(F)(F)Cl)c3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E06 compound treatment 0.353 0.0207 1.67 0.344 0.0224 2.03 2.6178 0.9952 1970081 MixCom2_000084 CC(C)C(NC(=O)OCCc1cccc(Cl)c1)C(=O)OCc2ccc(cc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E07 compound treatment 0.336 0.00372 0.3 0.329 0.0074 0.67 0.687 0.9339 1907800 MixCom2_000085 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCN=C(C=C2)C(F)(F)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E08 compound treatment 0.337 0.00472 0.38 0.327 0.0054 0.49 0.6156 0.9921 1970082 MixCom2_000086 CSc1sc(cc1c2nc(C)cs2)C(=O)NNC(=O)OCCN3C(=O)c4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E09 compound treatment 0.333 7.24E-4 0.06 0.325 0.0034 0.31 0.2595 0.8261 1907801 MixCom2_000087 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN=C(C=C2)C(F)(F)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E10 compound treatment 0.344 0.0117 0.94 0.332 0.0104 0.94 1.3351 1.0 1970083 MixCom2_000088 CCOc1ccsc1C(=O)NNC(=O)OCCC2CCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E11 compound treatment 0.358 0.0257 2.07 0.344 0.0224 2.03 2.9025 1.0 1907802 MixCom2_000089 FC(F)(Cl)C1=NCCN(C=C1)C(=O)c2ccc(Br)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E12 compound treatment 0.324 -0.00828 -0.67 0.313 -0.0086 -0.78 -1.0232 -0.9969 1970084 MixCom2_000090 CCn1c2ccccc2c3cc(CN4CCN(CC4)C(=O)OCc5cccc(c5)C(F)(F)F)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E13 compound treatment 0.333 7.24E-4 0.06 0.358 0.0364 3.3 2.3776 0.7195 1397671 MixCom2_000091 COc1ccc(Oc2ncc(CN3CCN(CC3)c4ccccc4)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E14 compound treatment 0.327 -0.00528 -0.42 0.35 0.0284 2.58 1.5224 0.5827 1970085 MixCom2_000092 Cc1nc(sc1C(=O)NNC(=O)OCc2ccc(/C=C/c3ccccc3)cc2)c4ccc(cc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E15 compound treatment 0.349 0.0167 1.35 0.338 0.0164 1.49 2.0049 0.9987 1708198 MixCom2_000093 Brc1ccc(Oc2ncc(Cn3ccc4ccccc34)s2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E16 compound treatment 0.358 0.0257 2.07 0.354 0.0324 2.94 3.5444 0.9853 1970086 MixCom2_000094 COc1ccc(CN2CCCC(COC(=O)N3CCN(CC3)c4cc(nc5cc(nn45)C(C)(C)C)C(F)(F)F)C2)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E17 compound treatment 0.33 -0.00228 -0.18 0.332 0.0104 0.94 0.5379 0.5594 1433082 MixCom2_000095 C(c1cnc(s1)N2CCN(CC2)c3ccccc3)n4ccc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E18 compound treatment 0.376 0.0437 3.52 0.364 0.0424 3.85 5.2111 0.999 1970087 MixCom2_000096 O=C(NNC(=O)c1snnc1c2ccccc2)OCCCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E19 compound treatment 0.33 -0.00228 -0.18 0.321 -6.0E-4 -0.05 -0.1681 -0.8792 1535695 MixCom2_000097 Cc1ccc(C)n1c2ccsc2c3cc4nccc(CCc5ccccc5)n4n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E20 compound treatment 0.341 0.00872 0.7 0.337 0.0154 1.4 1.4852 0.9493 1970088 MixCom2_000098 CCC#CCOC(=O)NNC(=O)Cc1ccc(OC)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E21 compound treatment 0.341 0.00872 0.7 0.339 0.0174 1.58 1.6136 0.9335 1254989 MixCom2_000099 Fc1ccccc1C(=O)n2cc(c3ccc(Cl)nn3)c4ccccc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E22 compound treatment 0.341 0.00872 0.7 0.332 0.0104 0.94 1.1643 0.9894 1970089 MixCom2_000100 Fc1ccc(/C=C/C(=O)NNC(=O)OCC2CC2(Cl)Cl)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E23 positive control 0.081 -0.251 -20.23 0.082 -0.24 -21.75 -29.6866 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 E24 positive control 0.086 -0.246 -19.83 0.085 -0.237 -21.48 -29.2093 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F01 mock treatment 0.328 -0.00428 -0.34 0.316 -0.0056 -0.51 -0.6029 -0.982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F02 mock treatment 0.333 7.24E-4 0.06 0.323 0.0014 0.13 0.1311 0.9376 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F03 compound treatment 0.327 -0.00528 -0.42 0.321 -6.0E-4 -0.05 -0.3389 -0.7913 1970090 MixCom2_000101 COCc1nc2ccc(Br)cc2c3C(=O)N(NC(=O)c4ccc(cc4)N(C)C)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F04 compound treatment 0.31 -0.0223 -1.79 0.295 -0.0266 -2.41 -2.9757 -0.9893 1970091 MixCom2_000102 COCCC(=O)N1CCN(CC1)c2ccc(cc2)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F05 compound treatment 0.347 0.0147 1.19 0.335 0.0134 1.22 1.6985 0.9999 1970092 MixCom2_000103 Cc1nc2ccc(Cl)cc2c3C(=O)N(CCN4CCCC4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F06 compound treatment 0.356 0.0237 1.91 0.336 0.0144 1.31 2.2751 0.9829 1970093 MixCom2_000104 Fc1ccc(cc1)C(=O)CCC(=O)NCC2COc3ccccc3O2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F07 compound treatment 0.339 0.00672 0.54 0.341 0.0194 1.76 1.6281 0.8837 1970094 MixCom2_000105 Cc1ccc2nc(C)c3C(=O)N(Cc4ccccn4)C(=O)c3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F08 compound treatment 0.35 0.0177 1.43 0.35 0.0284 2.58 2.8321 0.9611 1970095 MixCom2_000106 COc1ccc(cc1OC)C(=O)NNC(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F09 compound treatment 0.337 0.00472 0.38 0.36 0.0384 3.49 2.7337 0.7797 1970096 MixCom2_000107 COCc1nc2ccccc2c3C(=O)N(Cc4ccc(C)o4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F10 compound treatment 0.35 0.0177 1.43 0.347 0.0254 2.31 2.6395 0.9734 1970097 MixCom2_000108 Cc1nn(c(C)c1CN2CCC(C2)NC(=O)c3ccccc3c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F11 compound treatment 0.337 0.00472 0.38 0.335 0.0134 1.22 1.1291 0.8859 1970098 MixCom2_000109 Cc1ccc2nc(C)c3C(=O)N(NC(=O)c4ccccc4C)C(=O)c3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F12 compound treatment 0.349 0.0167 1.35 0.342 0.0204 1.85 2.2617 0.9878 1970099 MixCom2_000110 CC(=O)Nc1ccc(cc1NC(=O)C)C(=O)NCCOc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F13 compound treatment 0.335 0.00272 0.22 0.341 0.0194 1.76 1.4003 0.7891 1861039 MixCom2_000111 CC(C)(C)c1ccc(cc1)C(=O)NN2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F14 compound treatment 0.347 0.0147 1.19 0.364 0.0424 3.85 3.5599 0.884 1970100 MixCom2_000112 Cc1ccc(Oc2ncccc2C(=O)NNC(=O)C(Cc3c[nH]cn3)NC(=O)OC(C)(C)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F15 compound treatment 0.343 0.0107 0.86 0.356 0.0344 3.12 2.8186 0.87 1970101 MixCom2_000113 O=C1N(CCN2CCCCCC2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F16 compound treatment 0.336 0.00372 0.3 0.333 0.0114 1.03 0.9438 0.876 1970102 MixCom2_000114 CCCCCCc1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F17 compound treatment 0.347 0.0147 1.19 0.346 0.0244 2.21 2.4045 0.9571 1970103 MixCom2_000115 CC(=O)NC(Cc1ccccc1)C(=O)NN2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F18 compound treatment 0.341 0.00872 0.7 0.339 0.0174 1.58 1.6136 0.9335 1970104 MixCom2_000116 Fc1cc(F)cc(c1)C(=O)NNC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F19 compound treatment 0.37 0.0377 3.04 0.356 0.0344 3.12 4.356 0.9999 1970105 MixCom2_000117 CC(C)c1nc2ccc(F)cc2c3C(=O)N(CCN4CCCC4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F20 compound treatment 0.336 0.00372 0.3 0.328 0.0064 0.58 0.6228 0.9527 1970106 MixCom2_000118 CC(C)NC(=O)CN1CCN(CC1)C(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F21 compound treatment 0.336 0.00372 0.3 0.333 0.0114 1.03 0.9438 0.876 1970107 MixCom2_000119 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)C4CCCNC4=O)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F22 compound treatment 0.373 0.0407 3.28 0.369 0.0474 4.3 5.3612 0.991 1970108 MixCom2_000120 FC(F)(F)Oc1cccc(CNC(=O)c2ccc3[nH]nnc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F23 positive control 0.084 -0.248 -19.99 0.082 -0.24 -21.75 -29.5158 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 F24 positive control 0.086 -0.246 -19.83 0.086 -0.236 -21.39 -29.1452 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G01 mock treatment 0.329 -0.00328 -0.26 0.309 -0.0126 -1.14 -0.9953 -0.8479 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G02 mock treatment 0.329 -0.00328 -0.26 0.318 -0.0036 -0.33 -0.4176 -0.9944 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G03 compound treatment 0.328 -0.00428 -0.34 0.322 4.0E-4 0.04 -0.2178 -0.6291 1907803 MixCom2_000121 CCCCCCCc1ccc(cc1)C2NC(=S)NC3=C2C(=O)c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G04 compound treatment 0.341 0.00872 0.7 0.334 0.0124 1.13 1.2927 0.9743 1970109 MixCom2_000122 COc1ccc2ccccc2c1CN3CCN(CC3)C(=O)OCc4ccccc4OC(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G05 compound treatment 0.343 0.0107 0.86 0.338 0.0164 1.49 1.6633 0.9665 1410645 MixCom2_000123 Oc1cc2OCOc2cc1C(N3CCCC3)c4ccc(Br)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G06 compound treatment 0.338 0.00572 0.46 0.335 0.0134 1.22 1.186 0.9118 1970110 MixCom2_000124 Clc1ccccc1N2CCN(CC2)C(=O)OCC3CC4CCC3C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G07 compound treatment 0.334 0.00172 0.14 0.34 0.0184 1.67 1.2792 0.7633 1907804 MixCom2_000125 CC1C(c2ccc(Br)cc2)c3cc4OCOc4cc3OC1(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G08 compound treatment 0.338 0.00572 0.46 0.336 0.0144 1.31 1.2502 0.902 1970111 MixCom2_000126 COc1cc(Br)c(CN2CCN(CC2)C(=O)OCCCl)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G09 compound treatment 0.333 7.24E-4 0.06 0.339 0.0174 1.58 1.1581 0.7327 1662730 MixCom2_000127 Cc1ccc(cc1)C(=O)n2ccc(n2)c3ccc(cc3)n4cnc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G10 compound treatment 0.337 0.00472 0.38 0.334 0.0124 1.13 1.0649 0.8963 1970112 MixCom2_000128 Cc1ccc(s1)C(=O)NNC(=O)OCCN2CCN(CCCN3c4ccccc4Sc5ccc(cc35)C(F)(F)F)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G11 compound treatment 0.335 0.00272 0.22 0.327 0.0054 0.49 0.5017 0.9343 1907805 MixCom2_000129 Cc1ccc(N/C=C/C(=O)c2ccc(cc2)n3cnc4ccccc34)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G12 compound treatment 0.343 0.0107 0.86 0.329 0.0074 0.67 1.0856 0.9923 1970113 MixCom2_000130 Cc1ccc([N+](=O)[O-])c(COC(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G13 compound treatment 0.315 -0.0173 -1.39 0.305 -0.0166 -1.51 -2.0492 -0.9992 1907806 MixCom2_000131 CC(C)(C)c1ccc(cc1)C(=O)N/N=C/c2cccn2c3nccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G14 compound treatment 0.431 0.0987 7.95 0.426 0.104 9.48 12.3224 0.9962 1970114 MixCom2_000132 COC(COC(=O)NNC(=O)/C=C/c1ccco1)c2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G15 compound treatment 0.336 0.00372 0.3 0.332 0.0104 0.94 0.8796 0.888 1907807 MixCom2_000133 CCn1c(S)nnc1c2csc(n2)n3nc(C)cc3C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G16 compound treatment 0.329 -0.00328 -0.26 0.318 -0.0036 -0.33 -0.4176 -0.9944 1970115 MixCom2_000134 COc1ccc(CN2CCCC(COC(=O)N3CCN(CC3)C(=O)Cc4ccc(Br)cc4)C2)cc1OCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G17 compound treatment 0.354 0.0217 1.75 0.351 0.0294 2.67 3.124 0.979 1907808 MixCom2_000135 Cc1cc(n(n1)c2nc(cs2)c3nnc(S)n3CC=C)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G18 compound treatment 0.327 -0.00528 -0.42 0.325 0.0034 0.31 -0.0822 -0.1565 1970116 MixCom2_000136 CCOC(=O)C(Cc1ccccc1)NC(=O)OCCCc2ccc(OC)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G19 compound treatment 0.311 -0.0213 -1.71 0.296 -0.0256 -2.32 -2.8546 -0.9888 1553301 MixCom2_000137 COc1ccc(cc1)N2CCN(CC2)c3nc(cs3)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G20 compound treatment 0.329 -0.00328 -0.26 0.326 0.0044 0.4 0.0959 0.2003 1970117 MixCom2_000138 Clc1cc(ccn1)C(=O)NNC(=O)OC/C=C/COCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G21 compound treatment 0.347 0.0147 1.19 0.339 0.0174 1.58 1.9552 0.99 1261718 MixCom2_000139 Cc1ccc(cc1)S(=O)(=O)c2cnc3c(cnn3c2N)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G22 compound treatment 0.334 0.00172 0.14 0.33 0.0084 0.76 0.6373 0.8223 1970118 MixCom2_000140 CC(C)c1nc2ccccc2c3C(=O)N(NC(=O)c4cccc(C)c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G23 positive control 0.082 -0.25 -20.15 0.082 -0.24 -21.75 -29.6297 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 G24 positive control 0.087 -0.245 -19.75 0.085 -0.237 -21.48 -29.1524 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H01 mock treatment 0.336 0.00372 0.3 0.319 -0.0026 -0.24 0.0452 0.1184 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H02 mock treatment 0.331 -0.00128 -0.1 0.326 0.0044 0.4 0.2098 0.5086 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H03 compound treatment 0.341 0.00872 0.7 0.326 0.0044 0.4 0.7792 0.9642 1970119 MixCom2_000141 COCc1nc2ccc(Br)cc2c3C(=O)N(NC(=O)c4cnc(SC)n4C)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H04 compound treatment 0.289 -0.0433 -3.48 0.284 -0.0376 -3.41 -4.8775 -0.9999 1970120 MixCom2_000142 Cn1cccc1C(=O)NNC(=O)c2ccoc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H05 compound treatment 0.347 0.0147 1.19 0.336 0.0144 1.31 1.7627 0.9988 1970121 MixCom2_000143 Cc1nc2ccc(Cl)cc2c3C(=O)N(CC(O)c4ccccc4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H06 compound treatment 0.338 0.00572 0.46 0.323 0.0014 0.13 0.4158 0.8696 1970122 MixCom2_000144 Cc1cc(no1)c2onc(C)c2C(=O)NNC(=O)C(C3CCCC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H07 compound treatment 0.238 -0.0943 -7.59 0.256 -0.0656 -5.95 -9.5787 -0.9928 1970123 MixCom2_000145 CCn1c2ccccc2c3cc(CN4CCC(C4)N5C(=O)c6c(C5=O)c7cc(C)ccc7nc6C)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H08 compound treatment 0.338 0.00572 0.46 0.333 0.0114 1.03 1.0576 0.9336 1970124 MixCom2_000146 CCCCCCNC(=O)CCc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H09 compound treatment 0.346 0.0137 1.11 0.337 0.0154 1.4 1.7699 0.9932 1970125 MixCom2_000147 COCc1nc2ccccc2c3C(=O)N(CCOc4ccc(OC)cc4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H10 compound treatment 0.341 0.00872 0.7 0.337 0.0154 1.4 1.4852 0.9493 1970126 MixCom2_000148 CCn1c2ccccc2c3cc(CN4CCN(CC4)C(=O)c5cc(C)c([N+](=O)[O-])c(C)c5)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H11 compound treatment 0.331 -0.00128 -0.1 0.308 -0.0136 -1.23 -0.9456 -0.7633 1970127 MixCom2_000149 CCOc1cccc(c1)C(=O)NN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H12 compound treatment 0.322 -0.0103 -0.83 0.326 0.0044 0.4 -0.3027 -0.3294 1970128 MixCom2_000150 COC(=O)CCCC(=O)N1CCC(CC1)C(O)(c2ccccc2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H13 compound treatment 0.341 0.00872 0.7 0.335 0.0134 1.22 1.3568 0.966 1970129 MixCom2_000151 Fc1cccc(F)c1C(=O)Nc2ccccc2C(=O)NN3C(=O)c4ccccc4C3=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H14 compound treatment 0.343 0.0107 0.86 0.336 0.0144 1.31 1.5349 0.9798 1970130 MixCom2_000152 Cc1nn(c(C)c1CN2CCC(C2)NC(=O)CCN(Cc3ccco3)S(=O)(=O)c4cccc5nsnc45)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H15 compound treatment 0.331 -0.00128 -0.1 0.312 -0.0096 -0.87 -0.6888 -0.785 1970131 MixCom2_000153 O=C(NN1C(=O)c2ccccc2C1=O)c3ccco3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H16 compound treatment 0.331 -0.00128 -0.1 0.333 0.0114 1.03 0.6591 0.6338 1970132 MixCom2_000154 CC(C)C(NC(=O)Cc1c[nH]c2ccccc12)C(=O)NCCNC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H17 compound treatment 0.346 0.0137 1.11 0.329 0.0074 0.67 1.2564 0.9715 1970133 MixCom2_000155 CC1CCCCN1CCCN2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H18 compound treatment 0.326 -0.00628 -0.51 0.33 0.0084 0.76 0.1818 0.1987 1970134 MixCom2_000156 CC(C)(C)OC(=O)NC(CC1CCCCC1)C(=O)NNC(=O)c2ccc3nsnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H19 compound treatment 0.339 0.00672 0.54 0.331 0.0094 0.85 0.9862 0.9759 1970135 MixCom2_000157 CC(C)c1nc2ccc(F)cc2c3C(=O)N(CC(O)c4ccccc4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H20 compound treatment 0.365 0.0327 2.64 0.351 0.0294 2.67 3.7504 1.0 1970136 MixCom2_000158 CC(O)CNC(=O)CCc1c[nH]c2ccccc12 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H21 compound treatment 0.339 0.00672 0.54 0.335 0.0134 1.22 1.243 0.9336 1970137 MixCom2_000159 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)c4sccc4N(C)C)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H22 compound treatment 0.344 0.0117 0.94 0.335 0.0134 1.22 1.5277 0.9922 1970138 MixCom2_000160 CC(C)NC(=O)CN1CCN(CC1)C(=O)C2Cc3ccccc3CN2C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H23 positive control 0.084 -0.248 -19.99 0.083 -0.239 -21.66 -29.4516 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 H24 positive control 0.088 -0.244 -19.67 0.087 -0.235 -21.29 -28.9671 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I01 mock treatment 0.326 -0.00628 -0.51 0.319 -0.0026 -0.24 -0.5242 -0.9399 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I02 mock treatment 0.333 7.24E-4 0.06 0.322 4.0E-4 0.04 0.0669 0.974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I03 compound treatment 0.349 0.0167 1.35 0.341 0.0194 1.76 2.1975 0.9912 1128388 MixCom2_000161 Cc1ccc(C)n1c2ccsc2c3cc4ncc(c(N)n4n3)S(=O)(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I04 compound treatment 0.338 0.00572 0.46 0.329 0.0074 0.67 0.8009 0.9831 1970139 MixCom2_000162 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCCn3nc(cc3c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I05 compound treatment 0.341 0.00872 0.7 0.338 0.0164 1.49 1.5494 0.9413 1907809 MixCom2_000163 ClC1=C(N2CCC(CC2)C(=O)NC3CCCC3)C(=O)c4ccccc4C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I06 compound treatment 0.341 0.00872 0.7 0.336 0.0144 1.31 1.421 0.9576 1970140 MixCom2_000164 Clc1ccccc1N2CCN(CC2)C(=O)OCCc3ccccc3Br 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I07 compound treatment 0.312 -0.0203 -1.63 0.314 -0.0076 -0.69 -1.6423 -0.9266 1605572 MixCom2_000165 CC(C)(C)S(=O)(=O)c1cnc2c(cnn2c1N)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I08 compound treatment 0.312 -0.0203 -1.63 0.307 -0.0146 -1.33 -2.0916 -0.9946 1970141 MixCom2_000166 OC1CCCN(C1)C(=O)OCCc2ccccc2Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I09 compound treatment 0.323 -0.00928 -0.75 0.303 -0.0186 -1.69 -1.722 -0.9327 1907810 MixCom2_000167 COC(=O)CC(NC(=O)Nc1cccc(Cl)c1)c2cccc(F)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I10 compound treatment 0.527 0.195 15.68 0.512 0.19 17.28 23.3086 0.9988 1970142 MixCom2_000168 Cc1cc(no1)c2onc(C)c2COC(=O)N3CCN(CC3)c4ccc(cc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I11 compound treatment 0.337 0.00472 0.38 0.331 0.0094 0.85 0.8723 0.9338 1524704 MixCom2_000169 Cc1c(CS(=O)(=O)c2ccc(C)cc2)[nH]c(=O)n1c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I12 compound treatment 0.339 0.00672 0.54 0.325 0.0034 0.31 0.6011 0.9645 1970143 MixCom2_000170 Oc1ccc2[nH]cc(CCNC(=O)OCc3c(F)ccc(F)c3F)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I13 compound treatment 0.339 0.00672 0.54 0.322 4.0E-4 0.04 0.4086 0.7528 1907811 MixCom2_000171 CN(N1C(=O)C2C3OC(C=C3)C2C1=O)c4ncc(cc4Cl)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I14 compound treatment 0.349 0.0167 1.35 0.332 0.0104 0.94 1.6198 0.9849 1970144 MixCom2_000172 CSc1sc(cc1c2nc(C)cs2)C(=O)NNC(=O)OCC3CCC(=O)N3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I15 compound treatment 0.321 -0.0113 -0.91 0.33 0.0084 0.76 -0.1029 -0.0868 1907812 MixCom2_000173 N#Cc1c(SCc2ccccc2)nc(c3ccccc3)c4CCCCc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I16 compound treatment 0.332 -2.76E-4 -0.02 0.33 0.0084 0.76 0.5234 0.6862 1970145 MixCom2_000174 COc1cc(COC(=O)N2CCN(CC2)c3ccc(cc3)C(F)(F)F)ccc1OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I17 compound treatment 0.345 0.0127 1.02 0.329 0.0074 0.67 1.1995 0.979 1907813 MixCom2_000175 Fc1ccc(CSc2nc(c3ccccc3)c4CCCCc4c2C#N)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I18 compound treatment 0.369 0.0367 2.96 0.354 0.0324 2.94 4.1707 1.0 1970146 MixCom2_000176 CC(C)(C)OC(=O)C(Cc1ccc(OC(C)(C)C)cc1)NC(=O)OCCCCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I19 compound treatment 0.338 0.00572 0.46 0.336 0.0144 1.31 1.2502 0.902 1548341 MixCom2_000177 COC(=O)c1ccc(c(NC(=O)c2ccco2)c1)S(=O)(=O)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I20 compound treatment 0.344 0.0117 0.94 0.332 0.0104 0.94 1.3351 1.0 1970147 MixCom2_000178 Fc1cccc(CCOC(=O)NNC(=O)CNC(=O)c2c(F)cccc2F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I21 compound treatment 0.348 0.0157 1.27 0.334 0.0124 1.13 1.6912 0.9983 1484756 MixCom2_000179 COC(=O)c1ccc(N2CCN(CC2)c3ccccc3)c(NC(=O)C4CC4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I22 compound treatment 0.346 0.0137 1.11 0.339 0.0174 1.58 1.8983 0.9848 1970148 MixCom2_000180 CC(C)c1nc2ccccc2c3C(=O)N(NC(=O)c4cccc(C)c4O)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I23 positive control 0.083 -0.249 -20.07 0.082 -0.24 -21.75 -29.5727 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 I24 positive control 0.088 -0.244 -19.67 0.087 -0.235 -21.29 -28.9671 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J01 mock treatment 0.331 -0.00128 -0.1 0.318 -0.0036 -0.33 -0.3037 -0.8866 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J02 mock treatment 0.337 0.00472 0.38 0.319 -0.0026 -0.24 0.1021 0.2281 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J03 compound treatment 0.339 0.00672 0.54 0.329 0.0074 0.67 0.8578 0.9943 1970149 MixCom2_000181 COCc1nc2ccc(C)cc2c3C(=O)N(CCCn4ccnc4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J04 compound treatment 0.082 -0.25 -20.15 0.079 -0.243 -22.02 -29.8222 -0.999 1970150 MixCom2_000182 CC(C)(C)OC(=O)NCCCCC(=O)N1CCN(C/C=C/c2ccccc2)CC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J05 compound treatment 0.342 0.00972 0.78 0.328 0.0064 0.58 0.9645 0.9892 1970151 MixCom2_000183 Cc1nc2ccc(Cl)cc2c3C(=O)N(NC(=O)CC4(CC5CC6CC(C5)C4)C6)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J06 compound treatment 0.342 0.00972 0.78 0.345 0.0234 2.12 2.0556 0.908 1970152 MixCom2_000184 COc1cc(CN2CCC(C2)NC(=O)CNC(=O)c3ccccc3)cc4OCOc41 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J07 compound treatment 0.326 -0.00628 -0.51 0.322 4.0E-4 0.04 -0.3317 -0.6546 1970153 MixCom2_000185 Cc1ccc2nc(C)c3C(=O)N(NC(=O)/C=C/c4ccc(F)cc4Cl)C(=O)c3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J08 compound treatment 0.328 -0.00428 -0.34 0.327 0.0054 0.49 0.1031 0.1722 1970154 MixCom2_000186 OC1(Cc2ccccc2)CCN(CC1)C(=O)c3ccc4[nH]nnc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J09 compound treatment 0.344 0.0117 0.94 0.338 0.0164 1.49 1.7202 0.9759 1970155 MixCom2_000187 COCc1nc2ccccc2c3C(=O)N(CC(=O)Nc4ccc5ccccc5c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J10 compound treatment 0.335 0.00272 0.22 0.33 0.0084 0.76 0.6943 0.875 1970156 MixCom2_000188 COC(=O)CCc1c(C)nn(c1C)c2ccc(cc2)C(=O)NC(Cc3ccccc3)C(=O)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J11 compound treatment 0.35 0.0177 1.43 0.339 0.0174 1.58 2.126 0.9987 1970157 MixCom2_000189 CC(Oc1ccc(OC(F)(F)F)cc1)C(=O)NN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J12 compound treatment 0.342 0.00972 0.78 0.336 0.0144 1.31 1.478 0.97 1970158 MixCom2_000190 Cc1sc(nc1CC(=O)NNC(=O)c2cnn(c2C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J13 compound treatment 0.304 -0.0283 -2.28 0.306 -0.0156 -1.42 -2.6113 -0.9739 1970159 MixCom2_000191 Clc1ncn(Cc2nc(cs2)C(=O)NN3C(=O)c4ccccc4C3=O)c1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J14 compound treatment 0.351 0.0187 1.51 0.348 0.0264 2.4 2.7607 0.9751 1970160 MixCom2_000192 Fc1ccc(cc1)C(=O)CCC(=O)N2CCN(CC2)C(=O)Cc3ccc(F)c(F)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J15 compound treatment 0.305 -0.0273 -2.2 0.301 -0.0206 -1.87 -2.8753 -0.9968 1935349 MixCom2_000193 O=C(NN1C(=O)c2ccccc2C1=O)c3cccs3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J16 compound treatment 0.32 -0.0123 -0.99 0.314 -0.0076 -0.69 -1.1868 -0.9845 1970161 MixCom2_000194 OC(C1CCN(CC1)C(=O)CCCCCNC(=O)OCc2ccccc2)(c3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J17 compound treatment 0.331 -0.00128 -0.1 0.324 0.0024 0.22 0.0814 0.3379 1970162 MixCom2_000195 O=C1N(C2CCN(Cc3ccccc3)C2)C(=O)c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J18 compound treatment 0.309 -0.0233 -1.87 0.295 -0.0266 -2.41 -3.0327 -0.9922 1970163 MixCom2_000196 COc1cccc(CN2CCC(C2)NC(=O)CC(NC(=O)OC(C)(C)C)c3ccc(F)cc3)c1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J19 compound treatment 0.334 0.00172 0.14 0.335 0.0134 1.22 0.9583 0.7827 1970164 MixCom2_000197 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)Cc4ccccc4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J20 compound treatment 0.343 0.0107 0.86 0.339 0.0174 1.58 1.7275 0.9597 1970165 MixCom2_000198 O=C(NCCc1ccncc1)c2ccc3[nH]nnc3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J21 compound treatment 0.331 -0.00128 -0.1 0.33 0.0084 0.76 0.4665 0.6063 1970166 MixCom2_000199 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)c4csc(C)n4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J22 compound treatment 0.335 0.00272 0.22 0.336 0.0144 1.31 1.0794 0.8144 1970167 MixCom2_000200 CC1CC(CC(C)(C)C1)NC(=O)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J23 positive control 0.084 -0.248 -19.99 0.083 -0.239 -21.66 -29.4516 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 J24 positive control 0.089 -0.243 -19.59 0.087 -0.235 -21.29 -28.9101 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K01 mock treatment 0.266 -0.0663 -5.34 0.247 -0.0746 -6.77 -8.562 -0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K02 mock treatment 0.333 7.24E-4 0.06 0.319 -0.0026 -0.24 -0.1256 -0.5169 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K03 compound treatment 0.34 0.00772 0.62 0.336 0.0144 1.31 1.3641 0.9423 1577056 MixCom2_000201 COc1ccc(cc1)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K04 compound treatment 0.341 0.00872 0.7 0.338 0.0164 1.49 1.5494 0.9413 1970168 MixCom2_000202 CCn1c2ccccc2c3cc(CN(CCOC(=O)NC(Cc4cn(cn4)C(c5ccccc5)(c6ccccc6)c7ccccc7)C(=O)OC)C(=O)OC(C)(C)C)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K05 compound treatment 0.339 0.00672 0.54 0.331 0.0094 0.85 0.9862 0.9759 1907814 MixCom2_000203 ClC1=C(NC(=O)OC2CCCCCCC2)C(=O)c3ccccc3C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K06 compound treatment 0.34 0.00772 0.62 0.331 0.0094 0.85 1.0432 0.9879 1970169 MixCom2_000204 Clc1ccccc1N2CCN(CC2)C(=O)OCC3CC4CC3C=C4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K07 compound treatment 0.332 -2.76E-4 -0.02 0.335 0.0134 1.22 0.8444 0.6941 1907815 MixCom2_000205 FC(F)(F)c1cccc(c1)C(=O)n2nccc2c3ccc4OCOc4c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K08 compound treatment 0.343 0.0107 0.86 0.343 0.0214 1.94 1.9842 0.9334 1970170 MixCom2_000206 COc1ccccc1CCOC(=O)NNC(=O)c2ccc(F)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K09 compound treatment 0.325 -0.00728 -0.59 0.315 -0.0066 -0.6 -0.8379 -0.9999 1119315 MixCom2_000207 Oc1cc2OCOc2cc1C(N3CCCC3)c4ccc(Cl)c(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K10 compound treatment 0.338 0.00572 0.46 0.337 0.0154 1.4 1.3144 0.893 1970171 MixCom2_000208 COc1ccc(CN2CCCCC2COC(=O)N3CCN(CC3)c4ccc(cc4)C(F)(F)F)cc1F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K11 compound treatment 0.343 0.0107 0.86 0.335 0.0134 1.22 1.4707 0.9859 1133756 MixCom2_000209 CC1C(c2ccc(Cl)c(Cl)c2)c3cc4OCOc4cc3OC1(C)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K12 compound treatment 0.33 -0.00228 -0.18 0.332 0.0104 0.94 0.5379 0.5594 1970172 MixCom2_000210 COc1ccc2ccccc2c1CN3CCN(CC3)C(=O)OCc4ccc(OC(F)F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K13 compound treatment 0.457 0.125 10.04 0.449 0.127 11.56 15.2791 0.9975 1907816 MixCom2_000211 COc1ccc(OC)c(c1)C2C(C)C(C)(O)Oc3cc4OCOc4cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K14 compound treatment 0.393 0.0607 4.89 0.388 0.0664 6.03 7.7196 0.9946 1970173 MixCom2_000212 Fc1cccc(Cl)c1CN2CCC(C2)NC(=O)OCCN3CNC(=S)NC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K15 compound treatment 0.337 0.00472 0.38 0.34 0.0184 1.67 1.45 0.8465 1907817 MixCom2_000213 Cc1cc(n2nc(c(Cl)c2n1)c3cnn(C)c3C(F)(F)F)C(F)(F)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K16 compound treatment 0.332 -2.76E-4 -0.02 0.333 0.0114 1.03 0.716 0.6918 1970174 MixCom2_000214 NS(=O)(=O)c1cc([N+](=O)[O-])c(s1)N2CCN(CC2)C(=O)OCc3cccc(OCc4ccccc4)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K17 compound treatment 0.337 0.00472 0.38 0.329 0.0074 0.67 0.744 0.9637 1606077 MixCom2_000215 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K18 compound treatment 0.342 0.00972 0.78 0.328 0.0064 0.58 0.9645 0.9892 1970175 MixCom2_000216 Clc1ccc(CNC(=O)OCCCCCc2ccccc2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K19 compound treatment 0.337 0.00472 0.38 0.33 0.0084 0.76 0.8082 0.9484 1907818 MixCom2_000217 CN1CCN(CC1)c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cn2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K20 compound treatment 0.342 0.00972 0.78 0.335 0.0134 1.22 1.4138 0.9773 1970176 MixCom2_000218 COc1ccc(cc1)C(=O)NNC(=O)OCCC2=CCC3CC2C3(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K21 compound treatment 0.356 0.0237 1.91 0.35 0.0284 2.58 3.1737 0.9891 1907819 MixCom2_000219 FC(F)(F)c1cccc(c1)C(=O)Nc2ccc(C#Cc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K22 compound treatment 0.35 0.0177 1.43 0.346 0.0244 2.21 2.5753 0.9774 1970177 MixCom2_000220 CC(C)c1nc2ccccc2c3C(=O)N(NC(=O)c4ccc5OCOc5c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K23 positive control 0.082 -0.25 -20.15 0.082 -0.24 -21.75 -29.6297 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 K24 positive control 0.089 -0.243 -19.59 0.088 -0.234 -21.2 -28.846 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L01 mock treatment 0.352 0.0197 1.59 0.341 0.0194 1.76 2.3683 0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L02 mock treatment 0.334 0.00172 0.14 0.324 0.0024 0.22 0.2522 0.9763 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L03 compound treatment 0.338 0.00572 0.46 0.34 0.0184 1.67 1.5069 0.8697 1970178 MixCom2_000221 COCc1nc2ccc(C)cc2c3C(=O)N(CCc4c[nH]c5ccccc45)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L04 compound treatment 0.344 0.0117 0.94 0.339 0.0174 1.58 1.7844 0.9697 1970179 MixCom2_000222 FC(F)(F)c1cccc(NC(=O)C(=O)NNC(=O)c2ccc3[nH]nnc3c2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L05 compound treatment 0.344 0.0117 0.94 0.333 0.0114 1.03 1.3993 0.999 1970180 MixCom2_000223 CCCc1nc2ccccc2c3C(=O)N(CCN(CC)CC)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L06 compound treatment 0.344 0.0117 0.94 0.336 0.0144 1.31 1.5918 0.9872 1970181 MixCom2_000224 CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NNC(=O)c2ccco2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L07 compound treatment 0.332 -2.76E-4 -0.02 0.325 0.0034 0.31 0.2025 0.6545 1970182 MixCom2_000225 Cc1ccc2nc(C)c3C(=O)N(C4CCN(Cc5ccccc5Sc6ccc(Cl)cc6)C4)C(=O)c3c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L08 compound treatment 0.423 0.0907 7.31 0.41 0.0884 8.02 10.8399 0.9989 1970183 MixCom2_000226 CC(=O)c1ccc(cc1)N2CCN(CC2)C(=O)C3Cc4ccccc4CN3C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L09 compound treatment 0.332 -2.76E-4 -0.02 0.323 0.0014 0.13 0.0742 0.5748 1970184 MixCom2_000227 Cc1nn(c(C)c1CN2CCC(C2)N3C(=O)c4c(C3=O)c5cc(C)ccc5nc4C)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L10 compound treatment 0.347 0.0147 1.19 0.342 0.0204 1.85 2.1478 0.9768 1970185 MixCom2_000228 Cc1oc(nc1CC(=O)NC(CCCNC(=O)OCc2ccccc2)C(=O)OCc3ccccc3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L11 compound treatment 0.333 7.24E-4 0.06 0.329 0.0074 0.67 0.5162 0.7656 1970186 MixCom2_000229 O=C1CCCN1CCCN2C(=O)c3ccccc3C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L12 compound treatment 0.349 0.0167 1.35 0.339 0.0174 1.58 2.0691 0.9969 1970187 MixCom2_000230 CC(=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3cccnc3Oc4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L13 compound treatment 0.331 -0.00128 -0.1 0.328 0.0064 0.58 0.3381 0.5732 1970188 MixCom2_000231 CCOc1ccc(cc1)C(=O)NN2C(=O)c3c(C2=O)c4cc(F)ccc4nc3C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L14 compound treatment 0.316 -0.0163 -1.31 0.317 -0.0046 -0.42 -1.222 -0.8884 1970189 MixCom2_000232 CCn1c2ccccc2c3cc(CN4CCN(CC4)C(=O)CCCCC(=O)OC)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L15 compound treatment 0.347 0.0147 1.19 0.344 0.0224 2.03 2.2762 0.967 1970190 MixCom2_000233 COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L16 compound treatment 0.319 -0.0133 -1.07 0.314 -0.0076 -0.69 -1.2437 -0.9775 1970191 MixCom2_000234 O=C(N1CCN(CC1)c2cnccn2)c3ccc(cc3)n4nc(cc4c5ccccc5)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L17 compound treatment 0.334 0.00172 0.14 0.337 0.0154 1.4 1.0866 0.7735 1970192 MixCom2_000235 CC(C)c1nc2ccc(F)cc2c3C(=O)N(CCc4c[nH]cn4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L18 compound treatment 0.344 0.0117 0.94 0.335 0.0134 1.22 1.5277 0.9922 1970193 MixCom2_000236 COc1cccc(CN2CCC(C2)NC(=O)CCN(Cc3ccco3)S(=O)(=O)c4cccc5nsnc45)c1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L19 compound treatment 0.338 0.00572 0.46 0.332 0.0104 0.94 0.9935 0.9457 1970194 MixCom2_000237 COCc1nc2ccc(C)cc2c3C(=O)N(Cc4c(OC)cc(OC)cc4OC)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L20 compound treatment 0.345 0.0127 1.02 0.332 0.0104 0.94 1.392 0.9992 1970195 MixCom2_000238 O=C(NNC(=O)c1ccc(s1)c2ccccn2)OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L21 compound treatment 0.32 -0.0123 -0.99 0.32 -0.0016 -0.15 -0.8017 -0.8024 1970196 MixCom2_000239 CCCc1nc2ccccc2c3C(=O)N(Cc4ccccn4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L22 compound treatment 0.343 0.0107 0.86 0.335 0.0134 1.22 1.4707 0.9859 1970197 MixCom2_000240 Cc1nc(cn1CCC(=O)NNC(=O)c2ccc3nsnc3c2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L23 positive control 0.085 -0.247 -19.91 0.085 -0.237 -21.48 -29.2663 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 L24 positive control 0.09 -0.242 -19.51 0.088 -0.234 -21.2 -28.789 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M01 mock treatment 0.333 7.24E-4 0.06 0.316 -0.0056 -0.51 -0.3182 -0.6219 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M02 mock treatment 0.332 -2.76E-4 -0.02 0.324 0.0024 0.22 0.1383 0.6317 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M03 compound treatment 0.334 0.00172 0.14 0.33 0.0084 0.76 0.6373 0.8223 1245758 MixCom2_000241 Clc1ccc(cc1Cl)C(=O)Nc2ccc(C#Cc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M04 compound treatment 0.323 -0.00928 -0.75 0.32 -0.0016 -0.15 -0.6309 -0.8291 1970198 MixCom2_000242 CC(C)(C)OC(=O)N(CCOC(=O)N1CCN(CC1)c2ccccc2C#N)Cc3cc4ccccc4c5ccccc35 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M05 compound treatment 0.328 -0.00428 -0.34 0.314 -0.0076 -0.69 -0.7313 -0.9485 1907820 MixCom2_000243 Clc1ccc(cc1)S(=O)(=O)Nc2ccc(C#Cc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M06 compound treatment 0.361 0.0287 2.31 0.351 0.0294 2.67 3.5226 0.9975 1970199 MixCom2_000244 Cc1csc(C(=O)NNC(=O)OCc2ccc(F)cc2Cl)c1n3cccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M07 compound treatment 0.326 -0.00628 -0.51 0.326 0.0044 0.4 -0.0749 -0.1163 1452233 MixCom2_000245 Fc1ccc(cc1)S(=O)(=O)Nc2ccc(C#Cc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M08 compound treatment 0.398 0.0657 5.29 0.398 0.0764 6.93 8.6461 0.9911 1970200 MixCom2_000246 CCOC(=O)N1CCN(CC1)C(=O)OCCc2cccc(Cl)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M09 compound treatment 0.352 0.0197 1.59 0.346 0.0244 2.21 2.6892 0.9867 1907821 MixCom2_000247 Clc1ccc(/C=C/2\C(=O)N(N=C2c3ccccc3)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M10 compound treatment 0.322 -0.0103 -0.83 0.322 4.0E-4 0.04 -0.5594 -0.6754 1970201 MixCom2_000248 [O-][N+](=O)c1cc(CN2CCCCC2COC(=O)N3CCCC3C(=O)OCc4ccccc4)ccc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M11 compound treatment 0.33 -0.00228 -0.18 0.321 -6.0E-4 -0.05 -0.1681 -0.8792 1907822 MixCom2_000249 FC(F)(F)c1cccc(c1)C(=O)OCn2ncc(Cl)c(Cl)c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M12 compound treatment 0.362 0.0297 2.39 0.352 0.0304 2.76 3.6437 0.9975 1970202 MixCom2_000250 COc1cc(CN2CCC(C2)NC(=O)OCCn3nc(cc3c4ccccc4)c5ccccc5)cc6OCOc61 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M13 compound treatment 0.327 -0.00528 -0.42 0.323 0.0014 0.13 -0.2106 -0.4748 1907823 MixCom2_000251 FC(F)(F)c1ccc(cc1)C(=O)OCn2ncc(Cl)c(Cl)c2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M14 compound treatment 0.337 0.00472 0.38 0.333 0.0114 1.03 1.0007 0.9077 1970203 MixCom2_000252 O=C(NCCCn1ccnc1)OCc2ccc(C#Cc3ccccc3)s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M15 compound treatment 0.195 -0.137 -11.05 0.196 -0.126 -11.4 -15.8782 -0.9999 1907824 MixCom2_000253 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(OCC#C)C(=O)OCC#C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M16 compound treatment 0.386 0.0537 4.33 0.376 0.0544 4.94 6.5508 0.9978 1970204 MixCom2_000254 Fc1cccc(Cl)c1COC(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M17 compound treatment 0.306 -0.0263 -2.12 0.299 -0.0226 -2.05 -2.9468 -0.9999 1907825 MixCom2_000255 CCN(CC)CCNC(=O)c1cc2cc(Br)ccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M18 compound treatment 0.333 7.24E-4 0.06 0.332 0.0104 0.94 0.7088 0.7494 1970205 MixCom2_000256 CC(C)(C)c1ccc(COC(=O)NC(CSCc2ccccc2)C(=O)Nc3ccc4ccccc4c3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M19 compound treatment 0.331 -0.00128 -0.1 0.329 0.0074 0.67 0.4023 0.5921 1907826 MixCom2_000257 FC(F)(F)c1ccc2sc(cc2c1)C(=O)NCc3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M20 compound treatment 0.333 7.24E-4 0.06 0.324 0.0024 0.22 0.1953 0.8659 1970206 MixCom2_000258 COc1ccc2[nH]cc(CCNC(=O)OCC3CC4CCC3C4)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M21 compound treatment 0.33 -0.00228 -0.18 0.329 0.0074 0.67 0.3454 0.496 1907827 MixCom2_000259 Cc1ccc(C)n1c2ccsc2c3cc4nc(C)c(c(N)n4n3)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M22 compound treatment 0.333 7.24E-4 0.06 0.326 0.0044 0.4 0.3236 0.8018 1970207 MixCom2_000260 CC(C)c1nc2ccccc2c3C(=O)N(NC(=O)C(=O)N4CCCc5ccccc45)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M23 positive control 0.084 -0.248 -19.99 0.084 -0.238 -21.57 -29.3874 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 M24 positive control 0.09 -0.242 -19.51 0.089 -0.233 -21.11 -28.7248 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N01 mock treatment 0.361 0.0287 2.31 0.363 0.0414 3.76 4.2928 0.9728 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N02 mock treatment 0.335 0.00272 0.22 0.323 0.0014 0.13 0.245 0.9663 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N03 compound treatment 0.34 0.00772 0.62 0.33 0.0084 0.76 0.979 0.9949 1970208 MixCom2_000261 CCN1CCCC1CN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3COC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N04 compound treatment 0.343 0.0107 0.86 0.34 0.0184 1.67 1.7916 0.9529 1970209 MixCom2_000262 CC(=O)c1ccc(cc1)N2CCN(CC2)C(=O)C(COC(C)(C)C)NC(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N05 compound treatment 0.336 0.00372 0.3 0.334 0.0124 1.13 1.008 0.8653 1970210 MixCom2_000263 CCN(CC)CCN1C(=O)c2c(C1=O)c3cc(C)ccc3nc2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N06 compound treatment 0.342 0.00972 0.78 0.337 0.0154 1.4 1.5422 0.9625 1970211 MixCom2_000264 Cc1cc(nn1C)C(=O)NCc2ccc(cc2)S(=O)(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N07 compound treatment 0.327 -0.00528 -0.42 0.33 0.0084 0.76 0.2387 0.2735 1970212 MixCom2_000265 O=C(NN1C(=O)C2C(C3CCC2C=C3)C1=O)c4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N08 compound treatment 0.331 -0.00128 -0.1 0.336 0.0144 1.31 0.8516 0.6495 1970213 MixCom2_000266 Cn1cccc1C(=O)NNC(=O)c2ccc(s2)c3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N09 compound treatment 0.334 0.00172 0.14 0.339 0.0174 1.58 1.215 0.7663 1970214 MixCom2_000267 CCOc1ccccc1CN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N10 compound treatment 0.343 0.0107 0.86 0.339 0.0174 1.58 1.7275 0.9597 1970215 MixCom2_000268 CC1(C)C2CCC1(C)C(O)C2CC(=O)N3CCC(CC3)C(O)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N11 compound treatment 0.35 0.0177 1.43 0.349 0.0274 2.49 2.7679 0.9652 1970216 MixCom2_000269 OC1(CN2C(=O)c3ccccc3C2=O)CCCCC1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N12 compound treatment 0.281 -0.0513 -4.13 0.275 -0.0466 -4.23 -5.9107 -0.9999 1970217 MixCom2_000270 O=C(CCN(Cc1ccco1)S(=O)(=O)c2cccc3nsnc23)NCC4CCCO4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N13 compound treatment 0.317 -0.0153 -1.23 0.311 -0.0106 -0.96 -1.5502 -0.9926 1970218 MixCom2_000271 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)c4cncc(Br)c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N14 compound treatment 0.351 0.0187 1.51 0.345 0.0234 2.12 2.5681 0.9859 1970219 MixCom2_000272 Cc1ccc(cc1)C(=O)NC(CCCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N15 compound treatment 0.35 0.0177 1.43 0.345 0.0234 2.12 2.5112 0.9813 1970220 MixCom2_000273 O=C1N(CCc2ccncc2)C(=O)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N16 compound treatment 0.33 -0.00228 -0.18 0.323 0.0014 0.13 -0.0397 -0.1782 1970221 MixCom2_000274 CC(C)(C)c1cc(n(n1)c2ccc(cc2)C(=O)NC(CO)Cc3ccc(Cl)cc3)C(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N17 compound treatment 0.353 0.0207 1.67 0.345 0.0234 2.12 2.682 0.9929 1970222 MixCom2_000275 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)c4ccc(C)s4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N18 compound treatment 0.34 0.00772 0.62 0.335 0.0134 1.22 1.2999 0.9515 1970223 MixCom2_000276 COC(=O)CCCCC(=O)NNC(=O)C(Cc1c[nH]cn1)NC(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N19 compound treatment 0.364 0.0317 2.55 0.367 0.0454 4.12 4.7204 0.9736 1970224 MixCom2_000277 COCc1nc2ccc(C)cc2c3C(=O)N(CC4CCCO4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N20 compound treatment 0.34 0.00772 0.62 0.334 0.0124 1.13 1.2357 0.9609 1970225 MixCom2_000278 CC(C)(C)OC(=O)C(Cc1ccc(OC(C)(C)C)cc1)NC(=O)c2cc(=O)n([nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N21 compound treatment 0.344 0.0117 0.94 0.336 0.0144 1.31 1.5918 0.9872 1970226 MixCom2_000279 Cc1[nH]c2ccccc2c1SCC(=O)NN3C(=O)c4c(C3=O)c5cc(C)ccc5nc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N22 compound treatment 0.333 7.24E-4 0.06 0.337 0.0154 1.4 1.0297 0.736 1970227 MixCom2_000280 COC(=O)CCCCC(=O)N1CCN(CC1)c2ccc(cc2)C(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N23 positive control 0.085 -0.247 -19.91 0.085 -0.237 -21.48 -29.2663 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 N24 positive control 0.09 -0.242 -19.51 0.089 -0.233 -21.11 -28.7248 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O01 mock treatment 0.35 0.0177 1.43 0.339 0.0174 1.58 2.126 0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O02 mock treatment 0.342 0.00972 0.78 0.329 0.0074 0.67 1.0287 0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O03 compound treatment 0.344 0.0117 0.94 0.337 0.0154 1.4 1.656 0.9817 1907828 MixCom2_000281 Cc1nc2cc(nn2c(N)c1c3ccccc3)c4ccc(Cl)c(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O04 compound treatment 0.345 0.0127 1.02 0.336 0.0144 1.31 1.6488 0.9927 1913199 MixCom2_000282 COc1ccc2[nH]cc(CCNC(=O)OCCCl)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O05 compound treatment 0.34 0.00772 0.62 0.332 0.0104 0.94 1.1073 0.9795 1907829 MixCom2_000283 NNC(=O)c1cn2c(ccc3c(cc(nc32)C(F)(F)F)C(F)(F)F)n1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O06 compound treatment 0.337 0.00472 0.38 0.331 0.0094 0.85 0.8723 0.9338 1970228 MixCom2_000284 COc1ccc(CC(=O)NNC(=O)OCC2CC2(Cl)Cl)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O07 compound treatment 0.323 -0.00928 -0.75 0.333 0.0114 1.03 0.2035 0.1595 1907830 MixCom2_000285 FC(F)(F)c1cc(c2ccc3nc(cn3c2n1)c4ccccc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O08 compound treatment 0.344 0.0117 0.94 0.338 0.0164 1.49 1.7202 0.9759 1970229 MixCom2_000286 COc1cccc(CCOC(=O)N2CCC(CC2)C(=O)N)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O09 compound treatment 0.331 -0.00128 -0.1 0.33 0.0084 0.76 0.4665 0.6063 1907831 MixCom2_000287 FCCCSc1nc(c2ccc(Cl)cc2)c3CCCCc3c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O10 compound treatment 0.336 0.00372 0.3 0.334 0.0124 1.13 1.008 0.8653 1970230 MixCom2_000288 COc1cc(CN2CCN(CCOC(=O)NCc3ccc(F)c(Cl)c3)CC2)cc4OCOc41 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O11 compound treatment 0.338 0.00572 0.46 0.336 0.0144 1.31 1.2502 0.902 1907832 MixCom2_000289 FC(F)(F)c1cc(c2ccc3nc(cn3c2n1)c4nnco4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O12 compound treatment 0.348 0.0157 1.27 0.342 0.0204 1.85 2.2047 0.9828 1970231 MixCom2_000290 CCn1c2ccccc2c3cc(CN(CCOC(=O)N4CCN(CC4)C(=O)c5ccc(F)cc5Cl)C(=O)OC(C)(C)C)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O13 compound treatment 0.336 0.00372 0.3 0.334 0.0124 1.13 1.008 0.8653 1907833 MixCom2_000291 CCOC(=O)C1=C(C)N=C2SCCC(=O)N2C1c3cccc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O14 compound treatment 0.283 -0.0493 -3.97 0.284 -0.0376 -3.41 -5.2192 -0.9972 1970232 MixCom2_000292 COc1ccc(COC(=O)NNC(=O)c2noc(C)c2c3csc(C)n3)c(Cl)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O15 compound treatment 0.347 0.0147 1.19 0.338 0.0164 1.49 1.891 0.9936 1907834 MixCom2_000293 Fc1ccc(cc1)c2cn3c(ccc4c(cc(nc43)C(F)(F)F)C(F)(F)F)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O16 compound treatment 0.318 -0.0143 -1.15 0.318 -0.0036 -0.33 -1.0439 -0.8735 1970233 MixCom2_000294 FC(F)(F)c1ccccc1COC(=O)NCCc2c[nH]c3ccc(Cl)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O17 compound treatment 0.342 0.00972 0.78 0.339 0.0174 1.58 1.6705 0.9476 1907835 MixCom2_000295 Fc1ccc(CSc2nc(c3CCCc3c2C#N)c4ccccc4)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O18 compound treatment 0.345 0.0127 1.02 0.336 0.0144 1.31 1.6488 0.9927 1970234 MixCom2_000296 Cc1nn(c(C)c1CN2CCC(C2)NC(=O)OCCCCc3ccc(cc3)[N+](=O)[O-])c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O19 compound treatment 0.341 0.00872 0.7 0.341 0.0194 1.76 1.742 0.9188 1907836 MixCom2_000297 Cc1ccc(cc1)c2nc(SCc3ccc(F)cc3)c(C#N)c4CCCCc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O20 compound treatment 0.338 0.00572 0.46 0.33 0.0084 0.76 0.8651 0.9709 1970235 MixCom2_000298 COc1ccc2[nH]cc(CCNC(=O)OCCc3ccccc3Br)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O21 compound treatment 0.378 0.0457 3.68 0.373 0.0514 4.67 5.9027 0.9931 1907837 MixCom2_000299 Cc1ccc(cc1)c2nc(SCCC(=C(F)F)F)c(C#N)c3CCCCc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O22 compound treatment 0.34 0.00772 0.62 0.338 0.0164 1.49 1.4925 0.9251 1970236 MixCom2_000300 CC(C)c1nc2ccccc2c3C(=O)N(NC(=O)C4CCCNC4=O)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O23 positive control 0.086 -0.246 -19.83 0.084 -0.238 -21.57 -29.2735 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 O24 positive control 0.09 -0.242 -19.51 0.09 -0.232 -21.02 -28.6607 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P01 mock treatment 0.328 -0.00428 -0.34 0.322 4.0E-4 0.04 -0.2178 -0.6291 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P02 mock treatment 0.328 -0.00428 -0.34 0.318 -0.0036 -0.33 -0.4745 -0.9997 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P03 compound treatment 0.369 0.0367 2.96 0.37 0.0484 4.39 5.1977 0.9814 1970237 MixCom2_000301 Cc1nc2ccc(Cl)cc2c3C(=O)N(CCc4c[nH]cn4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P04 compound treatment 0.35 0.0177 1.43 0.348 0.0264 2.4 2.7037 0.9694 1970238 MixCom2_000302 CC1=NN(C(=O)C1)c2ccc(cc2)C(=O)N3CCC(CC3)C(O)(c4ccccc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P05 compound treatment 0.337 0.00472 0.38 0.327 0.0054 0.49 0.6156 0.9921 1970239 MixCom2_000303 Cc1ccc2nc(C)c3C(=O)N(C(=O)c3c2c1)c4ccccc4N5CCCCC5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P06 compound treatment 0.334 0.00172 0.14 0.327 0.0054 0.49 0.4448 0.873 1970240 MixCom2_000304 O=C(NCCCC(NC(=O)c1ccccc1COC(=O)c2ccccc2)C(=O)OCc3ccccc3)OCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P07 compound treatment 0.327 -0.00528 -0.42 0.333 0.0114 1.03 0.4313 0.3856 1970241 MixCom2_000305 COCc1nc2ccccc2c3C(=O)N(CCN4CCOCC4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P08 compound treatment 0.333 7.24E-4 0.06 0.335 0.0134 1.22 0.9013 0.7402 1970242 MixCom2_000306 CC(Cc1ccc(Cl)cc1)NC(=O)c2cc(=O)n([nH]2)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P09 compound treatment 0.335 0.00272 0.22 0.335 0.0134 1.22 1.0152 0.8214 1970243 MixCom2_000307 COc1ccc(CN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P10 compound treatment 0.339 0.00672 0.54 0.333 0.0114 1.03 1.1146 0.9544 1970244 MixCom2_000308 OS(=O)(=O)c1cccc(c1)C(=O)N2CCN(Cc3ccc(OCC=C)cc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P11 compound treatment 0.332 -2.76E-4 -0.02 0.324 0.0024 0.22 0.1383 0.6317 1970245 MixCom2_000309 CCN(CC)CCCC(C)N1C(=O)c2ccccc2C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P12 compound treatment 0.313 -0.0193 -1.55 0.31 -0.0116 -1.05 -1.8421 -0.9821 1970246 MixCom2_000310 CN(C)CCCNC(=O)CCC(=O)c1ccc(F)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P13 compound treatment 0.341 0.00872 0.7 0.335 0.0134 1.22 1.3568 0.966 1970247 MixCom2_000311 CC(C)c1nc2ccc(F)cc2c3C(=O)N(NC(=O)c4sc(nc4C)n5cccc5)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P14 compound treatment 0.325 -0.00728 -0.59 0.317 -0.0046 -0.42 -0.7095 -0.9862 1970248 MixCom2_000312 CC(=O)c1ccc(cc1)N2CCN(CC2)C(=O)C3CCN(CC3)C(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P15 compound treatment 0.332 -2.76E-4 -0.02 0.332 0.0104 0.94 0.6518 0.6903 1970249 MixCom2_000313 O=C(NN1C(=O)c2ccccc2C1=O)c3ccncc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P16 compound treatment 0.317 -0.0153 -1.23 0.311 -0.0106 -0.96 -1.5502 -0.9926 1970250 MixCom2_000314 CC(=O)Nc1ccc(cc1NC(=O)C)C(=O)N2CCN(CC2)c3nccnc3C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P17 compound treatment 0.329 -0.00328 -0.26 0.325 0.0034 0.31 0.0317 0.0781 1970251 MixCom2_000315 CSc1ccc(cc1)C(=O)NN2C(=O)c3c(C2=O)c4cc(F)ccc4nc3C(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P18 compound treatment 0.328 -0.00428 -0.34 0.333 0.0114 1.03 0.4882 0.4477 1970252 MixCom2_000316 CC(C)C(NC(=O)c1ccc(C)cc1)C(=O)OCc2ccccc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P19 compound treatment 0.27 -0.0623 -5.01 0.274 -0.0476 -4.32 -6.6012 -0.9972 1970253 MixCom2_000317 COCc1nc2ccc(C)cc2c3C(=O)N(NC(=O)c4cccc(C)c4)C(=O)c31 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P20 compound treatment 0.333 7.24E-4 0.06 0.331 0.0094 0.85 0.6446 0.7537 1970254 MixCom2_000318 Cc1cc(no1)c2onc(C)c2C(=O)NNC(=O)C(CCCCNC(=O)c3cccnc3)NC(=O)OC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P21 compound treatment 0.337 0.00472 0.38 0.334 0.0124 1.13 1.0649 0.8963 1970255 MixCom2_000319 COc1cscc1C(=O)NN2C(=O)c3c(C2=O)c4cc(C)ccc4nc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P22 compound treatment 0.329 -0.00328 -0.26 0.325 0.0034 0.31 0.0317 0.0781 1970256 MixCom2_000320 Cc1ccc(cc1)C(=O)NC(CCCCNC(=O)OCc2ccccc2)C(=O)OCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P23 positive control 0.088 -0.244 -19.67 0.087 -0.235 -21.29 -28.9671 -0.9992 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.567 P24 positive control 0.092 -0.24 -19.35 0.092 -0.23 -20.84 -28.4184 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A01 compound treatment 0.318 -0.0203 -1.63 0.318 -0.0242 -2.2 -2.7097 -0.9894 1483669 MixCom3_000001 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4CCC(CC4)C(=O)NCC5CCCO5)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A02 compound treatment 0.298 -0.0403 -3.25 0.296 -0.0462 -4.19 -5.2606 -0.992 1983416 MixCom3_000002 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(Br)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A03 compound treatment 0.313 -0.0253 -2.04 0.316 -0.0262 -2.38 -3.1228 -0.997 1434267 MixCom3_000003 O=C(CSc1nc2ccccc2c(=O)n1NC(=O)c3cccs3)NC4CCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A04 compound treatment 0.333 -0.0053 -0.43 0.337 -0.00521 -0.47 -0.6361 -0.9987 1983417 MixCom3_000004 CC1=NN(C(=O)C21C(c3ccccc3[N+](=O)[O-])C42C(=NN(C4=O)c5ccc(C)c(C)c5)C)c6ccc(C)c(C)c6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A05 compound treatment 0.309 -0.0293 -2.36 0.318 -0.0242 -2.2 -3.2222 -0.9994 1159710 MixCom3_000005 Clc1ccc2[nH]c(=S)n(Cc3ccccn3)c(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A06 compound treatment 0.31 -0.0283 -2.28 0.318 -0.0242 -2.2 -3.1653 -0.9998 1983418 MixCom3_000006 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2cccc3ccccc23)c4ccc(Cl)c(Cl)c4)S)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A07 compound treatment 0.312 -0.0263 -2.12 0.31 -0.0322 -2.92 -3.5649 -0.9875 1296718 MixCom3_000007 COc1ccc(Cl)cc1C(=O)Nc2c3CS(=O)(=O)Cc3nn2c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A08 compound treatment 0.307 -0.0313 -2.52 0.309 -0.0332 -3.01 -3.9138 -0.996 1983419 MixCom3_000008 CSc1nnc(c2ccco2)n1c3cccc(Cl)c3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A09 compound treatment 0.303 -0.0353 -2.84 0.308 -0.0342 -3.11 -4.2057 -0.999 1738349 MixCom3_000009 O=C(CSc1nc2ccccc2c(=O)n1CC3CCC(CC3)C(=O)NCc4ccco4)Nc5nccs5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A10 compound treatment 0.299 -0.0393 -3.16 0.304 -0.0382 -3.47 -4.6902 -0.999 1406547 MixCom3_000010 C(Nc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4)c5ccco5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A11 compound treatment 0.322 -0.0163 -1.31 0.322 -0.0202 -1.83 -2.2252 -0.9865 1562975 MixCom3_000011 C=CCn1c(SCC(=O)N2CCCC2)nc3cc(ccc3c1=O)C(=O)NCc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A12 compound treatment 0.306 -0.0323 -2.6 0.31 -0.0322 -2.92 -3.9065 -0.9983 1983420 MixCom3_000012 CCOc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5ccc(O)cc5)c6ccccc6C3c7ccccc74 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A13 compound treatment 0.309 -0.0293 -2.36 0.314 -0.0282 -2.56 -3.4789 -0.9992 1983421 MixCom3_000013 Cc1ccc(cc1)C2CC(n3nc(cc3N2)C(=O)NCc4ccccc4)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A14 compound treatment 0.362 0.0237 1.91 0.357 0.0148 1.34 2.2989 0.9852 1983422 MixCom3_000014 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccc(C)cc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A15 compound treatment 0.362 0.0237 1.91 0.366 0.0238 2.16 2.8765 0.9981 1182556 MixCom3_000015 CN1CC=C2C(C1)C(c3ccc(OC(=O)C)cc3)C(C#N)(C#N)C(=C2C#N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A16 compound treatment 0.323 -0.0153 -1.23 0.324 -0.0182 -1.65 -2.0399 -0.9895 1523000 MixCom3_000016 CCn1cnc2sc(C(=O)N3CCCCC3C)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A17 mock treatment 0.309 -0.0293 -2.36 0.316 -0.0262 -2.38 -3.3506 -1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A18 mock treatment 0.308 -0.0303 -2.44 0.313 -0.0292 -2.65 -3.6001 -0.9991 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A19 mock treatment 0.312 -0.0263 -2.12 0.315 -0.0272 -2.47 -3.2439 -0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A20 mock treatment 0.312 -0.0263 -2.12 0.317 -0.0252 -2.29 -3.1156 -0.9993 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A21 mock treatment 0.296 -0.0423 -3.41 0.313 -0.0292 -2.65 -4.2834 -0.9923 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A22 mock treatment 0.296 -0.0423 -3.41 0.306 -0.0362 -3.29 -4.7327 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A23 positive control 0.08 -0.258 -20.8 0.079 -0.263 -23.89 -31.6019 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 A24 positive control 0.083 -0.255 -20.56 0.081 -0.261 -23.71 -31.3027 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B01 compound treatment 0.32 -0.0183 -1.47 0.333 -0.00921 -0.84 -1.6331 -0.9639 1983423 MixCom3_000017 CC(=O)[C@@H]1[C@@H](c2ccccc2I)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B02 compound treatment 0.352 0.0137 1.1 0.361 0.0188 1.71 1.9862 0.9778 1911097 MixCom3_000018 Clc1ncc(Cn2cccc2/C=C(\C#N)/C(=O)c3ccccc3)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B03 compound treatment 0.34 0.0017 0.14 0.328 -0.0142 -1.29 -0.8152 -0.6285 1983424 MixCom3_000019 CCOCCn1cnc2sc(C(=O)NCCN(C)C)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B04 compound treatment 0.336 -0.0023 -0.19 0.35 0.00779 0.71 0.3691 0.5049 1911098 MixCom3_000020 COc1ccc(CNc2nc(nc3ccsc23)c4ccccc4Cl)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B05 compound treatment 0.317 -0.0213 -1.72 0.32 -0.0222 -2.02 -2.6383 -0.9968 1983425 MixCom3_000021 COc1ccc2oc(=O)c(cc2c1)c3nc(c4ccccc4)c5cc(Br)ccc5n3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B06 compound treatment 0.322 -0.0163 -1.31 0.333 -0.00921 -0.84 -1.5192 -0.9763 1911099 MixCom3_000022 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2ccccc2n3c(C)ccc3C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B07 compound treatment 0.333 -0.0053 -0.43 0.338 -0.00421 -0.38 -0.5719 -0.9985 2074522 MixCom3_000023 CCO/C(=N/Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])/C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B08 compound treatment 0.345 0.0067 0.54 0.356 0.0138 1.25 1.2667 0.9292 1911100 MixCom3_000024 Cc1ccc2SCC(NC(=O)c3cccc(c3)C(F)(F)F)C(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B09 compound treatment 0.342 0.0037 0.3 0.351 0.00879 0.8 0.7749 0.9098 1067370 MixCom3_000025 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCC)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B10 compound treatment 0.328 -0.0103 -0.83 0.333 -0.00921 -0.84 -1.1776 -1.0 2079820 MixCom3_000026 CN1CCN(CC1)C(=O)C2CCCN(C2)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B11 compound treatment 0.336 -0.0023 -0.19 0.342 -2.09E-4 -0.02 -0.1444 -0.7754 1911101 MixCom3_000027 CCOC(=O)c1cnc2n(C)ncc2c1NCc3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B12 compound treatment 0.336 -0.0023 -0.19 0.345 0.00279 0.25 0.0482 0.1536 2079821 MixCom3_000028 CCCCNC(=O)C1CCCN(Cc2ccncc2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B13 compound treatment 0.336 -0.0023 -0.19 0.337 -0.00521 -0.47 -0.4653 -0.9163 1911102 MixCom3_000029 CCC(N1C(C(C)N(C)C1=O)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B14 compound treatment 0.369 0.0307 2.47 0.362 0.0198 1.8 3.0184 0.9877 2079822 MixCom3_000030 CCCCCCCCCCCCNC(=O)C1CCCN(Cc2cccnc2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B15 compound treatment 0.334 -0.0043 -0.35 0.345 0.00279 0.25 -0.0657 -0.1531 1911103 MixCom3_000031 Fc1ccc(cc1)c2cnn3c(ccnc23)c4ccc(cc4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B16 compound treatment 0.335 -0.0033 -0.27 0.345 0.00279 0.25 -0.0088 -0.0238 2079823 MixCom3_000032 COC(=O)C1CCN(CC1)C2CCN(CC2)C(=O)c3ccccc3N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B17 compound treatment 0.338 -3.0E-4 -0.02 0.34 -0.00221 -0.2 -0.1589 -0.7866 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B18 compound treatment 0.338 -3.0E-4 -0.02 0.348 0.00579 0.53 0.3546 0.6739 1538303 MixCom3_000033 O=C(OCc1ccccc1)N2CCNC(=O)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B19 mock treatment 0.335 -0.0033 -0.27 0.343 7.91E-4 0.07 -0.1371 -0.4981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B20 mock treatment 0.337 -0.0013 -0.1 0.345 0.00279 0.25 0.1051 0.3835 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B21 mock treatment 0.324 -0.0143 -1.15 0.335 -0.00721 -0.65 -1.277 -0.9641 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B22 mock treatment 0.324 -0.0143 -1.15 0.33 -0.0122 -1.11 -1.5979 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B23 positive control 0.084 -0.254 -20.48 0.081 -0.261 -23.71 -31.2458 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 B24 positive control 0.083 -0.255 -20.56 0.082 -0.26 -23.62 -31.2385 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C01 compound treatment 0.324 -0.0143 -1.15 0.332 -0.0102 -0.93 -1.4695 -0.9942 1498486 MixCom3_000034 O=C(CSc1nc2ccccc2c(=O)n1NC(=O)c3cccs3)NCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C02 compound treatment 0.356 0.0177 1.43 0.371 0.0288 2.61 2.8558 0.9594 1414620 MixCom3_000035 Cc1cc2NC(=O)CC(c3ccc(F)cc3)c2cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C03 compound treatment 0.328 -0.0103 -0.83 0.33 -0.0122 -1.11 -1.3701 -0.9898 1135125 MixCom3_000036 COC(Cn1c(=O)c2cc(Cl)ccc2[nH]c1=S)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C04 compound treatment 0.343 0.0047 0.38 0.351 0.00879 0.8 0.8319 0.9419 1983426 MixCom3_000037 CCCCCCCOC(=O)c1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C05 compound treatment 0.331 -0.0073 -0.59 0.333 -0.00921 -0.84 -1.0067 -0.9852 1445658 MixCom3_000038 CCOc1ccc(NC(=O)CSc2nc3cc(ccc3c(=O)n2CCC4=CCCCC4)C(=O)OC)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C06 compound treatment 0.327 -0.0113 -0.91 0.327 -0.0152 -1.38 -1.6196 -0.9795 1427597 MixCom3_000039 Brc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C07 compound treatment 0.332 -0.0063 -0.51 0.337 -0.00521 -0.47 -0.6931 -0.9994 1667678 MixCom3_000040 Cc1ccc(cc1)c2nc(Nc3c(F)cccc3F)c4ccccc4n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C08 compound treatment 0.332 -0.0063 -0.51 0.337 -0.00521 -0.47 -0.6931 -0.9994 1983427 MixCom3_000041 CCOCCn1cnc2sc(C(=O)NC(C)CC)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C09 compound treatment 0.349 0.0107 0.86 0.353 0.0108 0.98 1.3019 0.998 1143131 MixCom3_000042 CCOC(=O)c1ccc(cc1)n2c(=S)sc3c(=O)n(CC4CCCO4)c(SCC(=O)NC5CCCCC5)nc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C10 compound treatment 0.306 -0.0323 -2.6 0.312 -0.0302 -2.74 -3.7781 -0.9997 1983428 MixCom3_000043 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)cc4F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C11 compound treatment 0.35 0.0117 0.94 0.351 0.00879 0.8 1.2305 0.9966 1241082 MixCom3_000044 COc1ccc(Nc2ncnc3n(cc(c4ccccc4)c23)c5cccc(Cl)c5)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C12 compound treatment 0.331 -0.0073 -0.59 0.336 -0.00621 -0.56 -0.8142 -0.9998 1983429 MixCom3_000045 O=C1C2C(C3c4ccccc4C2c5ccccc35)C(=O)N1CC6(CC7CC8CC(C7)C6)C8 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C13 compound treatment 0.362 0.0237 1.91 0.376 0.0338 3.07 3.5184 0.9739 1514276 MixCom3_000046 Fc1ccc(cc1C(=O)Nc2ccc(Br)cc2F)S(=O)(=O)N3CCN(CC3)c4cccc(Cl)c4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C14 compound treatment 0.323 -0.0153 -1.23 0.338 -0.00421 -0.38 -1.1413 -0.8848 1386236 MixCom3_000047 CC(C)(C)C1CC=C2C(C1)C(c3ccccc3)C(C#N)(C#N)C(=C2C#N)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C15 compound treatment 0.326 -0.0123 -0.99 0.335 -0.00721 -0.65 -1.1631 -0.9798 1475162 MixCom3_000048 CC(=O)Oc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C(=O)O)c5ccccc5C3c6ccccc64 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C16 compound treatment 0.346 0.0077 0.62 0.346 0.00379 0.34 0.6818 0.9614 1738262 MixCom3_000049 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncn(CC)c(=O)c3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C17 mock treatment 0.336 -0.0023 -0.19 0.338 -0.00421 -0.38 -0.4011 -0.9447 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C18 mock treatment 0.335 -0.0033 -0.27 0.337 -0.00521 -0.47 -0.5222 -0.9629 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C19 mock treatment 0.335 -0.0033 -0.27 0.337 -0.00521 -0.47 -0.5222 -0.9629 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C20 mock treatment 0.332 -0.0063 -0.51 0.339 -0.00321 -0.29 -0.5647 -0.9653 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C21 mock treatment 0.323 -0.0153 -1.23 0.329 -0.0132 -1.2 -1.719 -0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C22 mock treatment 0.322 -0.0163 -1.31 0.326 -0.0162 -1.47 -1.9685 -0.9984 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C23 positive control 0.08 -0.258 -20.8 0.08 -0.262 -23.8 -31.5377 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 C24 positive control 0.084 -0.254 -20.48 0.082 -0.26 -23.62 -31.1816 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D01 compound treatment 0.342 0.0037 0.3 0.348 0.00579 0.53 0.5824 0.9638 1983430 MixCom3_000050 COc1ccc(C2C3C(N4C(C5C(N24)C(=O)N(C5=O)c6ccc(Cl)c(Cl)c6)c7ccc(OC)cc7OC)C(=O)N(C3=O)c8ccc(Cl)c(Cl)c8)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D02 compound treatment 0.332 -0.0063 -0.51 0.342 -2.09E-4 -0.02 -0.3721 -0.733 1911104 MixCom3_000051 COc1cc(NC(=S)Nc2ccc3OCOc3c2)c(C#N)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D03 compound treatment 0.318 -0.0203 -1.63 0.329 -0.0132 -1.2 -2.0037 -0.9884 1983431 MixCom3_000052 Cc1cccc[n+]1C2C(C(=C(NC2(O)C3CC3)[C-](C#N)C#N)C#N)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D04 compound treatment 0.331 -0.0073 -0.59 0.335 -0.00721 -0.65 -0.8784 -0.9986 1911105 MixCom3_000053 COC(=O)c1cnc2cc(nn2c1N)c3sccc3n4c(C)ccc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D05 compound treatment 0.352 0.0137 1.1 0.36 0.0178 1.61 1.922 0.9827 1337417 MixCom3_000054 NC(=O)C1CCN(CC1)C(=O)c2ccc3c4nc5ccccc5n4c(=S)[nH]c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D06 compound treatment 0.316 -0.0223 -1.8 0.335 -0.00721 -0.65 -1.7325 -0.9065 1911106 MixCom3_000055 Cc1ccc(cc1)S(=O)(=O)NNC(=O)c2cc3cc4ccccc4nc3s2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D07 compound treatment 0.51 0.172 13.83 0.461 0.119 10.78 17.4014 0.9924 2074523 MixCom3_000056 [O-][N+](=O)c1ccc(cc1)N2CCCCCCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D08 compound treatment 0.341 0.0027 0.22 0.349 0.00679 0.62 0.5896 0.902 1911107 MixCom3_000057 COC(=O)c1ccccc1Sc2nc(nc3ccsc23)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D09 compound treatment 0.337 -0.0013 -0.1 0.346 0.00379 0.34 0.1693 0.4707 2074524 MixCom3_000058 OC(=O)c1cnc(O)c(Cl)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D10 compound treatment 0.317 -0.0213 -1.72 0.328 -0.0142 -1.29 -2.1248 -0.9901 2079824 MixCom3_000059 O=C(NCCc1ccccc1)C2CCCN(C2)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D11 compound treatment 0.337 -0.0013 -0.1 0.344 0.00179 0.16 0.0409 0.2117 1911108 MixCom3_000060 Fc1cccc(CSc2nc(cc(=O)n2c3ccccc3)C(F)(F)F)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D12 compound treatment 0.338 -3.0E-4 -0.02 0.34 -0.00221 -0.2 -0.1589 -0.7866 2079825 MixCom3_000061 O=C(NC1CCCCC1)C2CCCN(Cc3ccccn3)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D13 compound treatment 0.359 0.0207 1.67 0.356 0.0138 1.25 2.0639 0.99 1911109 MixCom3_000062 CC1C(N(CS(=O)(=O)c2ccc(C)cc2)C(=O)N1C)c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D14 compound treatment 0.326 -0.0123 -0.99 0.342 -2.09E-4 -0.02 -0.7138 -0.7205 2079826 MixCom3_000063 CN1CCC(CC1)NCCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D15 compound treatment 0.371 0.0327 2.63 0.385 0.0428 3.88 4.6085 0.9821 1911110 MixCom3_000064 CN(C)/C=C/C(=O)c1ccc(s1)N2CCN(CC2)c3cccc(Cl)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D16 compound treatment 0.339 7.0E-4 0.06 0.341 -0.00121 -0.11 -0.0377 -0.3058 2079827 MixCom3_000065 CN1CCC(CC1)N(CCN2CCOCC2)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D17 compound treatment 0.341 0.0027 0.22 0.35 0.00779 0.71 0.6538 0.8837 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D18 compound treatment 0.335 -0.0033 -0.27 0.348 0.00579 0.53 0.1838 0.312 1344033 MixCom3_000066 OC(=O)c1ccc(C#Cc2ccccc2)o1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D19 mock treatment 0.341 0.0027 0.22 0.347 0.00479 0.43 0.4613 0.9487 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D20 mock treatment 0.346 0.0077 0.62 0.347 0.00479 0.43 0.746 0.9849 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D21 mock treatment 0.325 -0.0133 -1.07 0.338 -0.00421 -0.38 -1.0275 -0.9036 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D22 mock treatment 0.331 -0.0073 -0.59 0.336 -0.00621 -0.56 -0.8142 -0.9998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D23 positive control 0.083 -0.255 -20.56 0.081 -0.261 -23.71 -31.3027 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 D24 positive control 0.086 -0.252 -20.32 0.085 -0.257 -23.35 -30.8751 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E01 compound treatment 0.333 -0.0053 -0.43 0.336 -0.00621 -0.56 -0.7003 -0.9906 1338666 MixCom3_000067 Clc1ccc2c(=O)n(Cc3ccccn3)c(=S)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E02 compound treatment 0.346 0.0077 0.62 0.36 0.0178 1.61 1.5804 0.9136 1440708 MixCom3_000068 Cc1c(sc2ncn(Cc3cccc(F)c3)c(=O)c12)C(=O)N4CCCc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E03 compound treatment 0.334 -0.0043 -0.35 0.338 -0.00421 -0.38 -0.515 -0.9988 1473398 MixCom3_000069 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCC(=O)NCCc4ccccc4)nc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E04 compound treatment 0.338 -3.0E-4 -0.02 0.348 0.00579 0.53 0.3546 0.6739 1156085 MixCom3_000070 S=c1sc2SCC3(CSc2s1)OCCO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E05 compound treatment 0.339 7.0E-4 0.06 0.35 0.00779 0.71 0.5399 0.7611 1574889 MixCom3_000071 CC(Oc1ccccc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E06 compound treatment 0.334 -0.0043 -0.35 0.336 -0.00621 -0.56 -0.6434 -0.9726 1983432 MixCom3_000072 NC(=S)N/N=C/1\c2ccccc2C(=O)C1(Cl)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E07 compound treatment 0.337 -0.0013 -0.1 0.346 0.00379 0.34 0.1693 0.4707 1437533 MixCom3_000073 Clc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CC4CCC(CC4)C(=O)NCc5ccco5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E08 compound treatment 0.33 -0.0083 -0.67 0.34 -0.00221 -0.2 -0.6144 -0.8805 1983433 MixCom3_000074 CC1(C)OCC(O1)[C@H]2O[C@@H]3OC(C)(C)OC3C2OC(=O)Nc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E09 compound treatment 0.36 0.0217 1.75 0.362 0.0198 1.8 2.5059 0.9999 1311946 MixCom3_000075 O=C(CSc1nc2ccccc2c(=O)n1CC3CCCO3)NCCc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E10 compound treatment 0.339 7.0E-4 0.06 0.345 0.00279 0.25 0.219 0.8438 1311719 MixCom3_000076 CCn1cnc2sc(C(=O)NCCN3CCOCC3)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E11 compound treatment 0.349 0.0107 0.86 0.347 0.00479 0.43 0.9168 0.9499 1725651 MixCom3_000077 COc1ccc(c2nc(no2)c3c(F)cccc3F)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E12 compound treatment 0.355 0.0167 1.34 0.359 0.0168 1.52 2.0287 0.9981 1606515 MixCom3_000078 CCOc1ccc(cc1)C(Nc2ccc(Br)cc2)P3(=S)OCC(C)(C)CO3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E13 compound treatment 0.318 -0.0203 -1.63 0.32 -0.0222 -2.02 -2.5814 -0.9946 1983434 MixCom3_000079 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4cc(C)ccc4C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E14 compound treatment 0.296 -0.0423 -3.41 0.322 -0.0202 -1.83 -3.7057 -0.9578 1983435 MixCom3_000080 Ic1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E15 compound treatment 0.337 -0.0013 -0.1 0.344 0.00179 0.16 0.0409 0.2117 1983436 MixCom3_000081 CCOc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5ccccc5C)c6ccccc6C3c7ccccc74 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E16 compound treatment 0.339 7.0E-4 0.06 0.345 0.00279 0.25 0.219 0.8438 1983437 MixCom3_000082 CCOCCn1cnc2sc(C(=O)N3CCCCC3CC)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E17 mock treatment 0.336 -0.0023 -0.19 0.341 -0.00121 -0.11 -0.2086 -0.9688 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E18 mock treatment 0.337 -0.0013 -0.1 0.349 0.00679 0.62 0.3619 0.5787 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E19 mock treatment 0.336 -0.0023 -0.19 0.342 -2.09E-4 -0.02 -0.1444 -0.7754 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E20 mock treatment 0.34 0.0017 0.14 0.347 0.00479 0.43 0.4043 0.8868 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E21 mock treatment 0.335 -0.0033 -0.27 0.339 -0.00321 -0.29 -0.3939 -0.999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E22 mock treatment 0.335 -0.0033 -0.27 0.331 -0.0112 -1.02 -0.9073 -0.8628 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E23 positive control 0.082 -0.256 -20.64 0.081 -0.261 -23.71 -31.3596 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 E24 positive control 0.088 -0.25 -20.16 0.085 -0.257 -23.35 -30.7613 -0.9973 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F01 compound treatment 0.332 -0.0063 -0.51 0.336 -0.00621 -0.56 -0.7572 -0.9986 1983438 MixCom3_000083 COc1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)[N+](=O)[O-])c4ccc(Oc5ccc(cc5)c6[nH]c(nc6c7ccc(cc7)[N+](=O)[O-])c8ccc(OC)cc8)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F02 compound treatment 0.336 -0.0023 -0.19 0.345 0.00279 0.25 0.0482 0.1536 1911111 MixCom3_000084 CCCCCC1CCC(CC1)c2ccc(NC(=O)Oc3ccccc3)cc2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F03 compound treatment 0.388 0.0497 4.0 0.378 0.0358 3.25 5.1272 0.9946 1983439 MixCom3_000085 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3I)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F04 compound treatment 0.342 0.0037 0.3 0.351 0.00879 0.8 0.7749 0.9098 1911112 MixCom3_000086 CN1C(=O)N(C)C(=O)C(=Cc2cccn2c3ccc(Br)cc3)C1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F05 compound treatment 0.339 7.0E-4 0.06 0.341 -0.00121 -0.11 -0.0377 -0.3058 1983440 MixCom3_000087 Cc1ccc(cc1S(=O)(=O)n2ccnc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F06 compound treatment 0.348 0.0097 0.78 0.352 0.00979 0.89 1.1808 0.9979 1911113 MixCom3_000088 CCn1c(COc2ccc(=O)n(n2)c3ccccc3)nnc1SCC=C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F07 compound treatment 0.448 0.11 8.83 0.451 0.109 9.88 13.2292 0.9985 2074525 MixCom3_000089 [O-][N+](=O)c1ccc(ON2C(=O)c3ccccc3C2=O)cc1[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F08 compound treatment 0.314 -0.0243 -1.96 0.325 -0.0172 -1.56 -2.4882 -0.9938 1911114 MixCom3_000090 Fc1ccc(cc1)C(=O)Nc2ccsc2C(=O)NCc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F09 compound treatment 0.26 -0.0783 -6.31 0.303 -0.0392 -3.56 -6.9751 -0.9634 2074526 MixCom3_000091 O=C1CC(Nc2ccccc2)C=C1Nc3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F10 compound treatment 0.321 -0.0173 -1.39 0.323 -0.0192 -1.74 -2.218 -0.9938 2079828 MixCom3_000092 Cc1ccc(CNC(=O)C2CCCN(C2)C3CCN(Cc4ccccc4)CC3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F11 compound treatment 0.353 0.0147 1.18 0.359 0.0168 1.52 1.9148 0.9922 1911115 MixCom3_000093 CCn1cc(n(Cc2ccc(Cl)cc2)c1=O)S(=O)(=O)c3ccc(C)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F12 compound treatment 0.326 -0.0123 -0.99 0.338 -0.00421 -0.38 -0.9705 -0.9142 2079829 MixCom3_000094 O=C(NCc1ccccc1)C2CCCN(Cc3ccccn3)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F13 compound treatment 0.349 0.0107 0.86 0.35 0.00779 0.71 1.1093 0.9952 1911116 MixCom3_000095 COc1cc(NC(=S)NCc2ccc(Cl)c(Cl)c2)c(C#N)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F14 compound treatment 0.338 -3.0E-4 -0.02 0.345 0.00279 0.25 0.1621 0.6368 2079830 MixCom3_000096 CC(=O)N1CCC(CC1)NCCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F15 compound treatment 0.357 0.0187 1.51 0.37 0.0278 2.52 2.8486 0.9696 1911117 MixCom3_000097 COc1ccc(cc1OC)S(=O)(=O)N2CCc3cc(OC)c(OC)cc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F16 compound treatment 0.342 0.0037 0.3 0.35 0.00779 0.71 0.7108 0.9262 2079831 MixCom3_000098 CN1CCC(CC1)N(CCN2CCOCC2)C(=O)CSCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F17 compound treatment 0.342 0.0037 0.3 0.348 0.00579 0.53 0.5824 0.9638 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F18 compound treatment 0.352 0.0137 1.1 0.359 0.0168 1.52 1.8578 0.9874 2074527 MixCom3_000099 FC(F)(F)c1cccc(NC(=O)C(=O)NCc2ccccc2)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F19 mock treatment 0.344 0.0057 0.46 0.345 0.00279 0.25 0.5037 0.9608 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F20 mock treatment 0.346 0.0077 0.62 0.351 0.00879 0.8 1.0027 0.9922 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F21 mock treatment 0.334 -0.0043 -0.35 0.34 -0.00221 -0.2 -0.3866 -0.9662 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F22 mock treatment 0.329 -0.0093 -0.75 0.34 -0.00221 -0.2 -0.6713 -0.8659 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F23 positive control 0.084 -0.254 -20.48 0.083 -0.259 -23.53 -31.1174 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 F24 positive control 0.087 -0.251 -20.24 0.086 -0.256 -23.26 -30.754 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G01 compound treatment 0.333 -0.0053 -0.43 0.332 -0.0102 -0.93 -0.957 -0.9381 1983441 MixCom3_000100 CCCCCn1c(SCC(=O)N2CCCC2)nc3cc(ccc3c1=O)C(=O)NCc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G02 compound treatment 0.315 -0.0233 -1.88 0.322 -0.0202 -1.83 -2.6238 -0.9999 1983442 MixCom3_000101 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G03 compound treatment 0.381 0.0427 3.44 0.38 0.0378 3.43 4.857 1.0 1383366 MixCom3_000102 CCCCN(C)c1ncnc2n(cc(c3ccccc3)c12)c4ccc(OC)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G04 compound treatment 0.345 0.0067 0.54 0.346 0.00379 0.34 0.6248 0.9764 1983443 MixCom3_000103 COc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G05 compound treatment 0.353 0.0147 1.18 0.358 0.0158 1.43 1.8506 0.9955 1634993 MixCom3_000104 Cc1ccc(cc1)c2nc(Nc3ccccc3F)c4ccccc4n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G06 compound treatment 0.321 -0.0173 -1.39 0.327 -0.0152 -1.38 -1.9613 -1.0 1983444 MixCom3_000105 CCCCCCCCCCCCN1C=C/C(=C\C=C(/C#N)\C(=O)ONc2ccccc2)/c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G07 compound treatment 0.373 0.0347 2.79 0.372 0.0298 2.7 3.888 0.9999 1417902 MixCom3_000106 CCOC(=O)c1ccc(cc1)n2c(=S)sc3c(=O)n(CC4CCCO4)c(SCC(=O)NCc5ccccc5)nc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G08 compound treatment 0.382 0.0437 3.52 0.403 0.0608 5.52 6.3902 0.9764 1983445 MixCom3_000107 Cc1c(/N=C/c2c(OC(=O)c3cccc4ccccc34)ccc5ccccc25)c(=O)n(c6ccccc6)n1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G09 compound treatment 0.373 0.0347 2.79 0.372 0.0298 2.7 3.888 0.9999 1403336 MixCom3_000108 COc1ccc(cc1)n2cc(c3ccccc3)c4c(NCC(C)C)ncnc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G10 compound treatment 0.336 -0.0023 -0.19 0.348 0.00579 0.53 0.2407 0.4319 1149116 MixCom3_000109 Cc1c(sc2ncn(C)c(=O)c12)C(=O)N3CCC(CC3)C(=O)N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G11 compound treatment 0.366 0.0277 2.23 0.372 0.0298 2.7 3.4894 0.9954 1238519 MixCom3_000110 Fc1ccc(cc1C(=O)Nc2ccc(Br)cc2F)S(=O)(=O)N3CCN(CC3)c4ccccc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G12 compound treatment 0.298 -0.0403 -3.25 0.307 -0.0352 -3.2 -4.5546 -1.0 1191183 MixCom3_000111 C1c2cc3ccccc3c(c2C[N+]14CCOCC4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G13 compound treatment 0.389 0.0507 4.08 0.393 0.0508 4.61 6.1469 0.9982 1566471 MixCom3_000112 Cc1cc2NC(=O)CC(c3ccccc3F)c2cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G14 compound treatment 0.407 0.0687 5.53 0.407 0.0648 5.88 8.0705 0.9995 1983446 MixCom3_000113 CCCCCCCCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccccc4)C(=O)CC(C)(C)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G15 compound treatment 0.347 0.0087 0.7 0.353 0.0108 0.98 1.188 0.9865 1983447 MixCom3_000114 CCOC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G16 compound treatment 0.326 -0.0123 -0.99 0.331 -0.0112 -1.02 -1.4198 -0.9999 1983448 MixCom3_000115 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4cccc(I)c4)S)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G17 mock treatment 0.34 0.0017 0.14 0.346 0.00379 0.34 0.3401 0.9184 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G18 mock treatment 0.342 0.0037 0.3 0.345 0.00279 0.25 0.3898 0.9967 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G19 mock treatment 0.343 0.0047 0.38 0.341 -0.00121 -0.11 0.19 0.4823 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G20 mock treatment 0.344 0.0057 0.46 0.35 0.00779 0.71 0.8246 0.9781 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G21 mock treatment 0.333 -0.0053 -0.43 0.337 -0.00521 -0.47 -0.6361 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G22 mock treatment 0.328 -0.0103 -0.83 0.338 -0.00421 -0.38 -0.8566 -0.9381 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G23 positive control 0.083 -0.255 -20.56 0.083 -0.259 -23.53 -31.1743 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 G24 positive control 0.088 -0.25 -20.16 0.087 -0.255 -23.17 -30.6329 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H01 compound treatment 0.356 0.0177 1.43 0.357 0.0148 1.34 1.9572 0.9996 1155483 MixCom3_000116 CN1C(=O)CCN=C(c2ccccc2)c3cc(Cl)ccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H02 compound treatment 0.32 -0.0183 -1.47 0.332 -0.0102 -0.93 -1.6973 -0.975 1911118 MixCom3_000117 O=C(Nc1ccc2OCOc2c1)N(Cc3ccccc3)Cc4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H03 compound treatment 0.311 -0.0273 -2.2 0.324 -0.0182 -1.65 -2.7232 -0.9901 1983449 MixCom3_000118 Ic1cccc(c1)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H04 compound treatment 0.388 0.0497 4.0 0.415 0.0728 6.61 7.5021 0.9712 1911119 MixCom3_000119 Brc1ccc(cc1)n2cccc2/C=C\3/C(=O)Nc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H05 compound treatment 0.334 -0.0043 -0.35 0.346 0.00379 0.34 -0.0015 -0.0031 2074528 MixCom3_000120 O=c1nc(c2ccccc2)c3ccccc3[nH]1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H06 compound treatment 0.31 -0.0283 -2.28 0.327 -0.0152 -1.38 -2.5876 -0.9712 1911120 MixCom3_000121 O/N=C(/c1cc2cc3ccccc3nc2s1)\c4ccc(Cl)cc4Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H07 compound treatment 0.488 0.15 12.05 0.493 0.151 13.69 18.2026 0.998 1099382 MixCom3_000122 Cc1ccn2c(cnc2c1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H08 compound treatment 0.338 -3.0E-4 -0.02 0.351 0.00879 0.8 0.5472 0.6854 1178265 MixCom3_000123 CCOC(=O)c1cc(NC(=O)c2ccccc2)c(=O)oc1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H09 compound treatment 0.331 -0.0073 -0.59 0.338 -0.00421 -0.38 -0.6858 -0.9782 1323395 MixCom3_000124 Nc1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H10 compound treatment 0.328 -0.0103 -0.83 0.341 -0.00121 -0.11 -0.6641 -0.7937 2079832 MixCom3_000125 COC(=O)C1CCN(CC1)C(=O)C2CCCN(C2)C3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H11 compound treatment 0.365 0.0267 2.15 0.37 0.0278 2.52 3.3041 0.9968 1911121 MixCom3_000126 COc1ccc(cc1OC)c2nc3ccc(cc3c(=O)[nH]2)N4CCCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H12 compound treatment 0.332 -0.0063 -0.51 0.344 0.00179 0.16 -0.2438 -0.4576 2079833 MixCom3_000127 O=C(NCCc1ccccc1)C2CCCN(Cc3cccnc3)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H13 compound treatment 0.378 0.0397 3.2 0.375 0.0328 2.98 4.3653 0.9994 1911122 MixCom3_000128 CCn1c(SCC(=O)c2ccc(C)cc2)nc(cc1=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H14 compound treatment 0.334 -0.0043 -0.35 0.332 -0.0102 -0.93 -0.9001 -0.9099 2079834 MixCom3_000129 CCCN1CCC(CC1)NCCN2CCOCC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H15 compound treatment 0.37 0.0317 2.55 0.371 0.0288 2.61 3.653 0.9999 1911123 MixCom3_000130 CC(=O)c1ccc(s1)N2CCN(CC2)c3cccc(c3)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H16 compound treatment 0.346 0.0077 0.62 0.344 0.00179 0.16 0.5534 0.8633 2079835 MixCom3_000131 CCCN1CCC(CC1)N(CCN2CCOCC2)C(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H17 compound treatment 0.35 0.0117 0.94 0.344 0.00179 0.16 0.7812 0.8171 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H18 compound treatment 0.326 -0.0123 -0.99 0.341 -0.00121 -0.11 -0.778 -0.7807 2074529 MixCom3_000132 NNC(=O)c1cc2ccccc2s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H19 mock treatment 0.34 0.0017 0.14 0.348 0.00579 0.53 0.4685 0.8625 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H20 mock treatment 0.349 0.0107 0.86 0.349 0.00679 0.62 1.0452 0.9865 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H21 mock treatment 0.334 -0.0043 -0.35 0.34 -0.00221 -0.2 -0.3866 -0.9662 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H22 mock treatment 0.334 -0.0043 -0.35 0.336 -0.00621 -0.56 -0.6434 -0.9726 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H23 positive control 0.084 -0.254 -20.48 0.085 -0.257 -23.35 -30.989 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 H24 positive control 0.09 -0.248 -19.99 0.094 -0.248 -22.53 -30.0697 -0.9982 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I01 compound treatment 0.349 0.0107 0.86 0.356 0.0138 1.25 1.4945 0.9834 1249110 MixCom3_000133 CCCN(CCC)c1ncnc2n(cc(c3ccccc3)c12)c4ccc(OC)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I02 compound treatment 0.343 0.0047 0.38 0.357 0.0148 1.34 1.217 0.8724 1983450 MixCom3_000134 CCOCCn1cnc2sc(C(=O)N(CC)CC)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I03 compound treatment 0.382 0.0437 3.52 0.39 0.0478 4.34 5.5558 0.9946 1983451 MixCom3_000135 CCc1c(C)sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Cl)cc4)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I04 compound treatment 0.321 -0.0173 -1.39 0.327 -0.0152 -1.38 -1.9613 -1.0 1402833 MixCom3_000136 Cc1cc2NC(=O)CC(c3cc(F)ccc3F)c2cc1C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I05 compound treatment 0.354 0.0157 1.26 0.366 0.0238 2.16 2.421 0.9675 1549005 MixCom3_000137 O=C(CSc1nc2ccccc2c(=O)n1CC3CCC(CC3)C(=O)NCc4ccco4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I06 compound treatment 0.312 -0.0263 -2.12 0.336 -0.00621 -0.56 -1.8961 -0.8652 1983452 MixCom3_000138 [O-][N+](=O)c1cc(cc2C(=C(C#N)C#N)c3cc(cc([N+](=O)[O-])c3-c21)S(=O)(=O)NC4CCCCC4)S(=O)(=O)NC5CCCCC5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I07 compound treatment 0.33 -0.0083 -0.67 0.353 0.0108 0.98 0.22 0.1855 1517182 MixCom3_000139 Clc1ccc2c(=O)n(c3cccc(c3)C(=O)NCc4ccccn4)c(=S)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I08 compound treatment 0.366 0.0277 2.23 0.367 0.0248 2.25 3.1685 1.0 1983453 MixCom3_000140 CC(=O)OCC1OC(Oc2cccc(C)c2C)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I09 compound treatment 0.358 0.0197 1.59 0.353 0.0108 0.98 1.8144 0.9732 1983454 MixCom3_000141 COc1ccc(c2nc(no2)c3cccc(c3)C(F)(F)F)c(OC)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I10 compound treatment 0.37 0.0317 2.55 0.36 0.0178 1.61 2.947 0.9756 1983455 MixCom3_000142 CCOCCn1cnc2sc(C(=O)N3C(C)CCc4cc(F)ccc34)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I11 compound treatment 0.311 -0.0273 -2.2 0.319 -0.0232 -2.11 -3.0441 -0.9998 1685265 MixCom3_000143 Oc1ccc(cc1O)C(=O)CSc2nc3ccccc3c(=O)n2CC4CCC(CC4)C(=O)NCCc5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I12 compound treatment 0.354 0.0157 1.26 0.358 0.0158 1.43 1.9075 0.998 1242528 MixCom3_000144 COc1ccc(OC)c(NC(=O)c2c(NCc3cccnc3)sc4CCCCCc24)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I13 compound treatment 0.388 0.0497 4.0 0.377 0.0348 3.16 5.063 0.9931 1363889 MixCom3_000145 Cc1c(sc2ncn(Cc3ccccc3Cl)c(=O)c12)C(=O)N4CCCc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I14 compound treatment 0.341 0.0027 0.22 0.335 -0.00721 -0.65 -0.309 -0.4481 1983456 MixCom3_000146 CC(C)(C)NS(=O)(=O)c1cc2C(=C(C#N)C#N)c3cc(cc([N+](=O)[O-])c3-c2c(c1)[N+](=O)[O-])S(=O)(=O)NC(C)(C)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I15 compound treatment 0.352 0.0137 1.1 0.365 0.0228 2.07 2.2429 0.9567 1913615 MixCom3_000147 Cc1ccc(cc1)c2cc3c4cccn4ccn3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I16 compound treatment 0.377 0.0387 3.12 0.377 0.0348 3.16 4.4367 1.0 1983457 MixCom3_000148 CCN(CC)c1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I17 mock treatment 0.365 0.0267 2.15 0.35 0.00779 0.71 2.0204 0.8926 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I18 mock treatment 0.351 0.0127 1.02 0.347 0.00479 0.43 1.0307 0.9274 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I19 mock treatment 0.347 0.0087 0.7 0.355 0.0128 1.16 1.3164 0.9707 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I20 mock treatment 0.35 0.0117 0.94 0.354 0.0118 1.07 1.423 0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I21 mock treatment 0.341 0.0027 0.22 0.34 -0.00221 -0.2 0.012 0.0405 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I22 mock treatment 0.333 -0.0053 -0.43 0.347 0.00479 0.43 0.0057 0.0094 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I23 positive control 0.084 -0.254 -20.48 0.085 -0.257 -23.35 -30.989 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 I24 positive control 0.09 -0.248 -19.99 0.088 -0.254 -23.07 -30.4548 -0.9975 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J01 compound treatment 0.361 0.0227 1.83 0.372 0.0298 2.7 3.2047 0.9818 1614812 MixCom3_000149 O=C(COc1ccccc1)Nc2ncnc3oc(c(c4ccccc4)c23)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J02 compound treatment 0.34 0.0017 0.14 0.345 0.00279 0.25 0.276 0.9582 1911124 MixCom3_000150 CN(C)S(=O)(=O)c1ccc(NC(=O)N2CCN(CC2)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J03 compound treatment 0.305 -0.0333 -2.68 0.33 -0.0122 -1.11 -2.6798 -0.9236 1983458 MixCom3_000151 CCCCCCCCCN1C=C/C(=C/C(=C2C(=O)c3ccccc3C2=O)C#N)/c4ccccc14 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J04 compound treatment 0.31 -0.0283 -2.28 0.339 -0.00321 -0.29 -1.8174 -0.791 1911125 MixCom3_000152 FC(F)(F)Oc1ccc(cc1)n2cccc2CC3C(=O)Nc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J05 compound treatment 0.334 -0.0043 -0.35 0.337 -0.00521 -0.47 -0.5792 -0.9883 1043414 MixCom3_000153 NC(=N)SCc1ccc(o1)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J06 compound treatment 0.326 -0.0123 -0.99 0.348 0.00579 0.53 -0.3287 -0.2931 1911126 MixCom3_000154 Fc1ccc(CSc2nnc(o2)c3cc4cc5ccccc5nc4s3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J07 compound treatment 0.333 -0.0053 -0.43 0.349 0.00679 0.62 0.1341 0.1789 1111259 MixCom3_000155 [O-][N+](=O)c1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J08 compound treatment 0.364 0.0257 2.07 0.358 0.0158 1.43 2.4769 0.9839 2079836 MixCom3_000156 COc1cc(OC)nc(n1)N2CCC(CC2)C(=O)N3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J09 compound treatment 0.374 0.0357 2.87 0.373 0.0308 2.79 4.0091 0.9999 1911127 MixCom3_000157 Brc1ccc(cc1)n2ccc(/C=C/3\C(=O)Nc4ccccc34)c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J10 compound treatment 0.298 -0.0403 -3.25 0.306 -0.0362 -3.29 -4.6188 -1.0 2079837 MixCom3_000158 CCCCCCCCCCCCNC(=O)C1CCCN(C1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J11 compound treatment 0.356 0.0177 1.43 0.356 0.0138 1.25 1.893 0.9979 1911128 MixCom3_000159 Cc1cc(n2nc(nc2n1)N3CCN(CC3)c4ccccc4)C(F)(F)Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J12 compound treatment 0.341 0.0027 0.22 0.349 0.00679 0.62 0.5896 0.902 2079838 MixCom3_000160 O=C(C1CCCN(Cc2ccncc2)C1)N3CCc4ccccc4C3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J13 compound treatment 0.365 0.0267 2.15 0.352 0.00979 0.89 2.1488 0.9236 1911129 MixCom3_000161 CCn1c(SCC(=O)c2ccc(Cl)cc2)nc(cc1=O)C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J14 compound treatment 0.327 -0.0113 -0.91 0.335 -0.00721 -0.65 -1.1061 -0.9869 1139024 MixCom3_000162 C(CN1CCOCC1)NC2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J15 compound treatment 0.343 0.0047 0.38 0.345 0.00279 0.25 0.4468 0.981 1911130 MixCom3_000163 Cc1ccc(cc1)S(=O)(=O)/C(=C\Nc2[nH]ncc2c3ccc(Cl)cc3)/C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J16 compound treatment 0.341 0.0027 0.22 0.348 0.00579 0.53 0.5254 0.9237 2079839 MixCom3_000164 OC(=O)CCC(=O)N(CCN1CCOCC1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J17 mock treatment 0.351 0.0127 1.02 0.343 7.91E-4 0.07 0.7739 0.7549 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J18 mock treatment 0.34 0.0017 0.14 0.346 0.00379 0.34 0.3401 0.9184 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J19 mock treatment 0.345 0.0067 0.54 0.347 0.00479 0.43 0.689 0.9943 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J20 mock treatment 0.352 0.0137 1.1 0.351 0.00879 0.8 1.3444 0.9874 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J21 mock treatment 0.333 -0.0053 -0.43 0.337 -0.00521 -0.47 -0.6361 -0.9987 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J22 mock treatment 0.332 -0.0063 -0.51 0.337 -0.00521 -0.47 -0.6931 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J23 positive control 0.085 -0.253 -20.4 0.086 -0.256 -23.26 -30.8679 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 J24 positive control 0.09 -0.248 -19.99 0.089 -0.253 -22.98 -30.3906 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K01 compound treatment 0.333 -0.0053 -0.43 0.334 -0.00821 -0.75 -0.8287 -0.965 1983459 MixCom3_000165 CCc1c(C)sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(C)cc4)c1C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K02 compound treatment 0.376 0.0377 3.04 0.376 0.0338 3.07 4.3156 1.0 1983460 MixCom3_000166 CCCCCCOc1ccc(OC2OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C2OC(=O)C)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K03 compound treatment 0.346 0.0077 0.62 0.357 0.0148 1.34 1.3878 0.9384 1474950 MixCom3_000167 COc1ccc(cc1)C2C3=C(Nc4ncnn24)c5ccccc5OC3c6ccc(SC)cc6 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K04 compound treatment 0.338 -3.0E-4 -0.02 0.353 0.0108 0.98 0.6756 0.6895 1983461 MixCom3_000168 CCSc1nnc(c2ccncc2)n1c3ccccc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K05 compound treatment 0.372 0.0337 2.71 0.371 0.0288 2.61 3.7669 0.9998 1983462 MixCom3_000169 O=C(CSc1nc2ccccc2c(=O)n1C3CC3)N4CCN(CC4)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K06 compound treatment 0.357 0.0187 1.51 0.36 0.0178 1.61 2.2067 0.9994 1983463 MixCom3_000170 CC(OC1C(NC(=O)C)C(OCc2ccccc2)OC3COC(OC13)c4ccccc4)C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K07 compound treatment 0.352 0.0137 1.1 0.378 0.0358 3.25 3.0774 0.8969 1456603 MixCom3_000171 COc1ccc(cc1)n2cc(c3ccccc3)c4c(NCC=C)ncnc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K08 compound treatment 0.303 -0.0353 -2.84 0.329 -0.0132 -1.2 -2.8578 -0.9263 1983464 MixCom3_000172 Cc1ccc(cc1)C(=O)[C@H]2[C@H](c3ccccc3I)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K09 compound treatment 0.372 0.0337 2.71 0.359 0.0168 1.52 2.9967 0.9628 1683624 MixCom3_000173 CCN(c1cccc(C)c1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N(CCc4ccccc4)Cc5ccccc5)c(=O)c3c2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K10 compound treatment 0.301 -0.0373 -3.0 0.332 -0.0102 -0.93 -2.7791 -0.8841 1983465 MixCom3_000174 CC(=O)[C@@H]1[C@@H](c2cccc(I)c2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K11 compound treatment 0.334 -0.0043 -0.35 0.331 -0.0112 -1.02 -0.9643 -0.8972 1132204 MixCom3_000175 COC(Cn1c(=O)c2ccc(Cl)cc2[nH]c1=S)OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K12 compound treatment 0.341 0.0027 0.22 0.346 0.00379 0.34 0.3971 0.9755 1278221 MixCom3_000176 CCn1cnc2sc(C(=O)N3CCN(C)CC3)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K13 compound treatment 0.308 -0.0303 -2.44 0.314 -0.0282 -2.56 -3.5359 -0.9997 1983466 MixCom3_000177 OC1(C[N+](=C2SCCCN21)c3ccc(Br)cc3)c4ccc(cc4)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K14 compound treatment 0.346 0.0077 0.62 0.345 0.00279 0.25 0.6176 0.922 1408258 MixCom3_000178 Nc1nc2n(C3OC(CO)C(O)C3O)c(nc2c(=O)[nH]1)N4CCOCC4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K15 mock treatment 0.347 0.0087 0.7 0.34 -0.00221 -0.2 0.3536 0.4853 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K16 mock treatment 0.344 0.0057 0.46 0.345 0.00279 0.25 0.5037 0.9608 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K17 mock treatment 0.337 -0.0013 -0.1 0.351 0.00879 0.8 0.4902 0.6091 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K18 mock treatment 0.344 0.0057 0.46 0.342 -2.09E-4 -0.02 0.3112 0.6773 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K19 mock treatment 0.344 0.0057 0.46 0.343 7.91E-4 0.07 0.3753 0.8079 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K20 mock treatment 0.343 0.0047 0.38 0.347 0.00479 0.43 0.5751 0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K21 mock treatment 0.331 -0.0073 -0.59 0.334 -0.00821 -0.75 -0.9425 -0.9931 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K22 mock treatment 0.332 -0.0063 -0.51 0.339 -0.00321 -0.29 -0.5647 -0.9653 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K23 positive control 0.083 -0.255 -20.56 0.085 -0.257 -23.35 -31.046 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 K24 positive control 0.091 -0.247 -19.91 0.089 -0.253 -22.98 -30.3337 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L01 compound treatment 0.34 0.0017 0.14 0.344 0.00179 0.16 0.2118 0.9963 1530607 MixCom3_000179 CC1CCCN(C1)C(=O)c2sc3ncn(C)c(=O)c3c2C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L02 compound treatment 0.337 -0.0013 -0.1 0.345 0.00279 0.25 0.1051 0.3835 1911131 MixCom3_000180 CN(C)S(=O)(=O)c1ccc(NC(=O)N2CCN(CC2)c3ccccn3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L03 compound treatment 0.324 -0.0143 -1.15 0.34 -0.00221 -0.2 -0.956 -0.8179 1983467 MixCom3_000181 CC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2[N+](=O)[O-])SCc3ccc(cc3)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L04 compound treatment 0.348 0.0097 0.78 0.359 0.0168 1.52 1.6301 0.9518 1911132 MixCom3_000182 COc1cc2C(NC(=O)C(F)(F)F)/C(=C/N(C)C)/C(=O)c2cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L05 compound treatment 0.42 0.0817 6.58 0.421 0.0788 7.15 9.7093 0.9991 353 MixCom3_000183 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L06 compound treatment 0.335 -0.0033 -0.27 0.343 7.91E-4 0.07 -0.1371 -0.4981 1911133 MixCom3_000184 Cc1ccc(CSc2nnc(o2)c3cc4cc5ccccc5nc4s3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L07 compound treatment 0.349 0.0107 0.86 0.343 7.91E-4 0.07 0.6601 0.7634 1287531 MixCom3_000185 CS(=O)(=O)c1ccc2nc(N)sc2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L08 compound treatment 0.336 -0.0023 -0.19 0.344 0.00179 0.16 -0.016 -0.0649 2079840 MixCom3_000186 CCCCCCCCCCCCNC(=O)C1CCN(CC1)c2nc(OC)cc(OC)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L09 compound treatment 0.344 0.0057 0.46 0.347 0.00479 0.43 0.6321 0.9996 1911134 MixCom3_000187 Brc1ccc(cc1)n2cccc2C(=O)NCCc3ccccn3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L10 compound treatment 0.335 -0.0033 -0.27 0.342 -2.09E-4 -0.02 -0.2013 -0.7556 2079841 MixCom3_000188 OC(=O)C1CCCN(Cc2ccccn2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L11 compound treatment 0.345 0.0067 0.54 0.35 0.00779 0.71 0.8816 0.9911 1911135 MixCom3_000189 Nc1c(cnc2cc(nn12)c3ccc(Cl)c(Cl)c3)c4ccc(Cl)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L12 compound treatment 0.339 7.0E-4 0.06 0.35 0.00779 0.71 0.5399 0.7611 2079842 MixCom3_000190 Clc1ccc(CNC(=O)C2CCCN(Cc3cccnc3)C2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L13 compound treatment 0.343 0.0047 0.38 0.341 -0.00121 -0.11 0.19 0.4823 1911136 MixCom3_000191 COc1ccccc1CNC(=S)Nc2cc(OC)c(OC)cc2C#N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L14 compound treatment 0.336 -0.0023 -0.19 0.347 0.00479 0.43 0.1766 0.3735 2079843 MixCom3_000192 COC(=O)C1CCN(CC1)C2CCN(CC2)C(=O)/C=C\C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L15 mock treatment 0.34 0.0017 0.14 0.35 0.00779 0.71 0.5969 0.8286 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L16 compound treatment 0.341 0.0027 0.22 0.346 0.00379 0.34 0.3971 0.9755 1028887 MixCom3_000193 OC(=O)c1cccc(I)c1C(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L17 mock treatment 0.347 0.0087 0.7 0.35 0.00779 0.71 0.9955 1.0 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L18 mock treatment 0.349 0.0107 0.86 0.352 0.00979 0.89 1.2377 0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L19 mock treatment 0.344 0.0057 0.46 0.348 0.00579 0.53 0.6963 0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L20 mock treatment 0.352 0.0137 1.1 0.347 0.00479 0.43 1.0876 0.9172 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L21 mock treatment 0.333 -0.0053 -0.43 0.338 -0.00421 -0.38 -0.5719 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L22 mock treatment 0.338 -3.0E-4 -0.02 0.337 -0.00521 -0.47 -0.3514 -0.7423 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L23 positive control 0.086 -0.252 -20.32 0.088 -0.254 -23.07 -30.6826 -0.998 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 L24 positive control 0.091 -0.247 -19.91 0.091 -0.251 -22.8 -30.2053 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M01 compound treatment 0.357 0.0187 1.51 0.36 0.0178 1.61 2.2067 0.9994 1983468 MixCom3_000194 Fc1ccc(cc1C(=O)Nc2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)NCc3ccccc3Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M02 compound treatment 0.339 7.0E-4 0.06 0.338 -0.00421 -0.38 -0.2303 -0.5963 1983469 MixCom3_000195 Ic1cccc(c1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M03 compound treatment 0.334 -0.0043 -0.35 0.345 0.00279 0.25 -0.0657 -0.1531 1212579 MixCom3_000196 O=C(CSc1nc2ccccc2c(=O)n1CC3CCC(CC3)C(=O)NCC4CCCO4)NC5CCCC5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M04 compound treatment 0.367 0.0287 2.31 0.371 0.0288 2.61 3.4822 0.9981 1983470 MixCom3_000197 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4ccc(F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M05 compound treatment 0.36 0.0217 1.75 0.361 0.0188 1.71 2.4417 0.9999 1192970 MixCom3_000198 Clc1ccc2c(=O)n(c3cccc(c3)C(=O)NCc4ccccc4)c(=S)[nH]c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M06 compound treatment 0.316 -0.0223 -1.8 0.316 -0.0262 -2.38 -2.952 -0.9904 1983471 MixCom3_000199 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M07 compound treatment 0.346 0.0077 0.62 0.356 0.0138 1.25 1.3236 0.9475 1983472 MixCom3_000200 Cc1cccc(c1)N(CCOC(=O)c2ccc([N+](=O)[O-])c(C)c2)C3=NS(=O)(=O)c4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M08 compound treatment 0.341 0.0027 0.22 0.357 0.0148 1.34 1.1031 0.811 1983473 MixCom3_000201 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Oc2ccccc2/C=N/NC(=O)C3(CCC3)C(=O)N\N=C/c4ccccc4OS(=O)(=O)c5ccc(cc5)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M09 compound treatment 0.346 0.0077 0.62 0.352 0.00979 0.89 1.0669 0.9845 1468233 MixCom3_000202 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4CCC(CC4)C(=O)NCc5ccco5)cc1Cl 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M10 compound treatment 0.288 -0.0503 -4.05 0.299 -0.0432 -3.92 -5.6375 -0.9999 1216007 MixCom3_000203 NC(=O)C1C(c2cccc(I)c2)C(C#N)(C#N)C3N1C=Cc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M11 compound treatment 0.341 0.0027 0.22 0.346 0.00379 0.34 0.3971 0.9755 1366300 MixCom3_000204 C=CCn1c(SCC(=O)c2ccccc2)nc3cc(ccc3c1=O)C(=O)NCc4ccco4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M12 compound treatment 0.352 0.0137 1.1 0.348 0.00579 0.53 1.1518 0.9425 1983474 MixCom3_000205 CCn1cnc2sc(C(=O)N3CCC(CC3)(N4CCCCC4)C(=O)N)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M13 compound treatment 0.358 0.0197 1.59 0.352 0.00979 0.89 1.7502 0.9625 1983475 MixCom3_000206 CCOCCn1cnc2sc(C(=O)N3CCN(Cc4ccccc4)CC3)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M14 compound treatment 0.372 0.0337 2.71 0.36 0.0178 1.61 3.0608 0.9693 1944615 MixCom3_000207 CC(=O)c1c(C)oc2c1cc(O)c3n(nc(c4ccccc4)c23)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M15 mock treatment 0.338 -3.0E-4 -0.02 0.342 -2.09E-4 -0.02 -0.0305 -0.9928 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M16 mock treatment 0.34 0.0017 0.14 0.338 -0.00421 -0.38 -0.1733 -0.4271 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M17 mock treatment 0.339 7.0E-4 0.06 0.343 7.91E-4 0.07 0.0906 0.9928 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M18 mock treatment 0.341 0.0027 0.22 0.345 0.00279 0.25 0.3329 0.9971 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M19 mock treatment 0.336 -0.0023 -0.19 0.344 0.00179 0.16 -0.016 -0.0649 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M20 mock treatment 0.342 0.0037 0.3 0.336 -0.00621 -0.56 -0.1878 -0.2946 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M21 mock treatment 0.328 -0.0103 -0.83 0.334 -0.00821 -0.75 -1.1134 -0.9986 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M22 mock treatment 0.329 -0.0093 -0.75 0.335 -0.00721 -0.65 -0.9922 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M23 positive control 0.085 -0.253 -20.4 0.086 -0.256 -23.26 -30.8679 -0.9979 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 M24 positive control 0.092 -0.246 -19.83 0.09 -0.252 -22.89 -30.2126 -0.9974 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N01 compound treatment 0.337 -0.0013 -0.1 0.344 0.00179 0.16 0.0409 0.2117 1677023 MixCom3_000208 CCCn1cnc2sc(C(=O)N3CCCc4ccccc34)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N02 compound treatment 0.335 -0.0033 -0.27 0.341 -0.00121 -0.11 -0.2655 -0.9235 1911137 MixCom3_000209 Nc1c(cnc2c(cnn12)c3cccs3)S(=O)(=O)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N03 compound treatment 0.331 -0.0073 -0.59 0.342 -2.09E-4 -0.02 -0.4291 -0.7295 1171251 MixCom3_000210 COC1Cc2ccccc2N(C(=O)N)c3ccccc13 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N04 compound treatment 0.323 -0.0153 -1.23 0.334 -0.00821 -0.75 -1.3981 -0.971 1911138 MixCom3_000211 CCOC(=O)c1cnn(c2nc(cs2)c3cccc(N)c3)c1C(F)(F)F 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N05 compound treatment 0.336 -0.0023 -0.19 0.34 -0.00221 -0.2 -0.2727 -0.9992 2074530 MixCom3_000212 Cc1cc(C)c(O)c(N=Nc2ccc(Cl)cc2[N+](=O)[O-])c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N06 compound treatment 0.362 0.0237 1.91 0.366 0.0238 2.16 2.8765 0.9981 1911139 MixCom3_000213 Fc1cc(NC(=O)CN2CCOCC2)ccc1N3CCN(CC3)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N07 compound treatment 0.359 0.0207 1.67 0.37 0.0278 2.52 2.9625 0.9798 2074531 MixCom3_000214 CCOC(=O)C1=C(C)NC(=C(C1/C=C/c2ccccc2)C(=O)OCC)C 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N08 compound treatment 0.339 7.0E-4 0.06 0.35 0.00779 0.71 0.5399 0.7611 2079844 MixCom3_000215 OC(=O)C1CCCN(C1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N09 compound treatment 0.345 0.0067 0.54 0.357 0.0148 1.34 1.3309 0.9198 1911140 MixCom3_000216 Clc1cccc(Oc2ccccc2C3CC(=O)CC(=O)C3n4cncn4)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N10 compound treatment 0.34 0.0017 0.14 0.344 0.00179 0.16 0.2118 0.9963 2079845 MixCom3_000217 OC(=O)C1CCCN(Cc2cccnc2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N11 compound treatment 0.328 -0.0103 -0.83 0.356 0.0138 1.25 0.2987 0.1989 1911141 MixCom3_000218 Cc1ccc(N/C=C/C(=O)c2ccc3noc(c4cccc(F)c4)c3c2)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N12 compound treatment 0.356 0.0177 1.43 0.353 0.0108 0.98 1.7005 0.9832 2079846 MixCom3_000219 CCOC(=O)C1CCN(CC1)C(=O)C2CCCN(Cc3ccncc3)C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N13 compound treatment 0.317 -0.0213 -1.72 0.323 -0.0192 -1.74 -2.4458 -1.0 1911142 MixCom3_000220 COc1cc(/N=C(\NCc2ccc(F)cc2)/SC)c(C#N)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N14 compound treatment 0.343 0.0047 0.38 0.347 0.00479 0.43 0.5751 0.9976 2079847 MixCom3_000221 COC(=O)C1CCN(CC1)C2CCN(CC2)C(=O)CCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N15 mock treatment 0.341 0.0027 0.22 0.349 0.00679 0.62 0.5896 0.902 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N16 compound treatment 0.343 0.0047 0.38 0.345 0.00279 0.25 0.4468 0.981 1670164 MixCom3_000222 Cc1nc2ccccc2c(C(=O)O)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N17 mock treatment 0.346 0.0077 0.62 0.342 -2.09E-4 -0.02 0.425 0.6852 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N18 mock treatment 0.345 0.0067 0.54 0.348 0.00579 0.53 0.7532 0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N19 mock treatment 0.336 -0.0023 -0.19 0.347 0.00479 0.43 0.1766 0.3735 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N20 mock treatment 0.346 0.0077 0.62 0.347 0.00479 0.43 0.746 0.9849 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N21 mock treatment 0.339 7.0E-4 0.06 0.34 -0.00221 -0.2 -0.1019 -0.4893 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N22 mock treatment 0.33 -0.0083 -0.67 0.338 -0.00421 -0.38 -0.7428 -0.9648 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N23 positive control 0.087 -0.251 -20.24 0.087 -0.255 -23.17 -30.6898 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 N24 positive control 0.091 -0.247 -19.91 0.091 -0.251 -22.8 -30.2053 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O01 compound treatment 0.352 0.0137 1.1 0.356 0.0138 1.25 1.6653 0.998 1201763 MixCom3_000223 CCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1CC3CCC(CC3)C(=O)NCC4CCCO4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O02 compound treatment 0.37 0.0317 2.55 0.373 0.0308 2.79 3.7814 0.999 1983476 MixCom3_000224 CC(=O)Oc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O03 compound treatment 0.323 -0.0153 -1.23 0.337 -0.00521 -0.47 -1.2055 -0.9135 1983477 MixCom3_000225 COc1ccc(CCNC(=O)CSc2nc3ccccc3c(=O)n2C4CC4)cc1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O04 compound treatment 0.326 -0.0123 -0.99 0.333 -0.00921 -0.84 -1.2914 -0.9964 1072643 MixCom3_000226 Nc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O05 compound treatment 0.33 -0.0083 -0.67 0.342 -2.09E-4 -0.02 -0.486 -0.7269 1325773 MixCom3_000227 COc1cccc(Nc2ncnc3n(cc(c4ccccc4)c23)c5ccc(Cl)cc5)c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O06 compound treatment 0.343 0.0047 0.38 0.345 0.00279 0.25 0.4468 0.981 1288735 MixCom3_000228 Cc1ccccc1C2CC(=O)Nc3cc(C)c(C)cc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O07 compound treatment 0.36 0.0217 1.75 0.382 0.0398 3.61 3.7896 0.9445 1983478 MixCom3_000229 CCOCCCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCc4ccccc34 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O08 compound treatment 0.347 0.0087 0.7 0.334 -0.00821 -0.75 -0.0315 -0.0308 1983479 MixCom3_000230 [O-][N+](=O)c1ccc(cc1)c2nc([nH]c2c3ccc(Oc4ccc(cc4)c5nc([nH]c5c6ccc(cc6)[N+](=O)[O-])c7cccc(c7)[N+](=O)[O-])cc3)c8cccc(c8)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O09 compound treatment 0.34 0.0017 0.14 0.344 0.00179 0.16 0.2118 0.9963 1665434 MixCom3_000231 Brc1ccc2[nH]c(=S)n(Cc3ccccn3)c(=O)c2c1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O10 compound treatment 0.377 0.0387 3.12 0.377 0.0348 3.16 4.4367 1.0 1983480 MixCom3_000232 Ic1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O11 compound treatment 0.397 0.0587 4.73 0.397 0.0548 4.97 6.8592 0.9997 1627468 MixCom3_000233 COc1cc(Nc2ncnc3n(cc(c4ccccc4)c23)c5cccc(Cl)c5)cc(OC)c1OC 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O12 compound treatment 0.355 0.0167 1.34 0.357 0.0148 1.34 1.9003 1.0 1983481 MixCom3_000234 CCOCCn1cnc2sc(C(=O)N3CCCCC3C)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O13 compound treatment 0.363 0.0247 1.99 0.36 0.0178 1.61 2.5484 0.9947 1983482 MixCom3_000235 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc(Oc4ccc(cc4)c5nc([nH]c5c6ccccc6)c7ccc(cc7)[N+](=O)[O-])cc3)c8ccccc8 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O14 compound treatment 0.329 -0.0093 -0.75 0.349 0.00679 0.62 -0.0937 -0.0966 1225447 MixCom3_000236 CCOc1ccccc1NC(=O)c2c(NCc3cccnc3)sc4CCCCCc24 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O15 mock treatment 0.346 0.0077 0.62 0.329 -0.0132 -1.2 -0.4094 -0.3033 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O16 mock treatment 0.345 0.0067 0.54 0.352 0.00979 0.89 1.01 0.9714 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O17 mock treatment 0.344 0.0057 0.46 0.35 0.00779 0.71 0.8246 0.9781 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O18 mock treatment 0.345 0.0067 0.54 0.348 0.00579 0.53 0.7532 0.9999 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O19 mock treatment 0.341 0.0027 0.22 0.348 0.00579 0.53 0.5254 0.9237 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O20 mock treatment 0.349 0.0107 0.86 0.345 0.00279 0.25 0.7884 0.8779 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O21 mock treatment 0.339 7.0E-4 0.06 0.34 -0.00221 -0.2 -0.1019 -0.4893 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O22 mock treatment 0.338 -3.0E-4 -0.02 0.343 7.91E-4 0.07 0.0337 0.4448 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O23 positive control 0.086 -0.252 -20.32 0.086 -0.256 -23.26 -30.811 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 O24 positive control 0.092 -0.246 -19.83 0.091 -0.251 -22.8 -30.1484 -0.9976 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P01 compound treatment 0.336 -0.0023 -0.19 0.342 -2.09E-4 -0.02 -0.1444 -0.7754 1319070 MixCom3_000237 CCn1cnc2sc(C(=O)N3CC(C)CC(C)C3)c(C)c2c1=O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P02 compound treatment 0.349 0.0107 0.86 0.354 0.0118 1.07 1.3661 0.9942 1911143 MixCom3_000238 COc1cc(cc(OC)c1OC)C(=O)N2CCc3cc(OC)c(OC)cc3C2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P03 compound treatment 0.33 -0.0083 -0.67 0.342 -2.09E-4 -0.02 -0.486 -0.7269 1423863 MixCom3_000239 COc1ccc(cc1)C2Nc3ccc(Br)cc3C(O2)c4ccccc4 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P04 compound treatment 0.322 -0.0163 -1.31 0.334 -0.00821 -0.75 -1.455 -0.964 1911144 MixCom3_000240 Cc1ccc(C)n1c2ccccc2CNS(=O)(=O)c3ccc(Cl)cc3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P05 compound treatment 0.427 0.0887 7.14 0.429 0.0868 7.88 10.6214 0.9988 2074532 MixCom3_000241 CC1CCCN(C1)c2ccc(cc2)[N+](=O)[O-] 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P06 compound treatment 0.339 7.0E-4 0.06 0.343 7.91E-4 0.07 0.0906 0.9928 1911145 MixCom3_000242 COc1ccc(CNC(=O)c2sccc2NC(=O)c3ccccc3)cc1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P07 compound treatment 0.319 -0.0193 -1.55 0.334 -0.00821 -0.75 -1.6258 -0.9433 2074533 MixCom3_000243 [O-][N+](=O)c1ccc(cc1)N2CCc3ccccc23 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P08 compound treatment 0.334 -0.0043 -0.35 0.339 -0.00321 -0.29 -0.4508 -0.9963 2079848 MixCom3_000244 COCCNC(=O)C1CCCN(C1)C2CCN(Cc3ccccc3)CC2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P09 compound treatment 0.336 -0.0023 -0.19 0.336 -0.00621 -0.56 -0.5295 -0.8925 1911146 MixCom3_000245 Cc1ccc(cc1)c2cn3c(ccc4c(cc(nc43)C(F)(F)F)C(F)(F)F)n2 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P10 compound treatment 0.336 -0.0023 -0.19 0.333 -0.00921 -0.84 -0.722 -0.8433 2079849 MixCom3_000246 OC(=O)C1CCCN(Cc2ccncc2)C1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P11 compound treatment 0.335 -0.0033 -0.27 0.328 -0.0142 -1.29 -1.0999 -0.8353 1911147 MixCom3_000247 CN1CCN(CC1)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P12 compound treatment 0.342 0.0037 0.3 0.341 -0.00121 -0.11 0.1331 0.4192 2079850 MixCom3_000248 O=C(C1CCCN(Cc2ccccn2)C1)N3CCN(Cc4ccccc4)CC3 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P13 compound treatment 0.343 0.0047 0.38 0.342 -2.09E-4 -0.02 0.2542 0.6709 1911148 MixCom3_000249 CCNC(=O)Nc1nnc(SCc2cccc(c2)C(F)(F)F)s1 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P14 compound treatment 0.339 7.0E-4 0.06 0.338 -0.00421 -0.38 -0.2303 -0.5963 2079851 MixCom3_000250 COC(=O)C1CCN(CC1)C2CCN(CC2)C(=O)COCC(=O)O 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P15 mock treatment 0.333 -0.0053 -0.43 0.338 -0.00421 -0.38 -0.5719 -0.9985 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P16 compound treatment 0.336 -0.0023 -0.19 0.337 -0.00521 -0.47 -0.4653 -0.9163 2074534 MixCom3_000251 COC(=O)c1sc(SC)c(C#N)c1N 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P17 mock treatment 0.336 -0.0023 -0.19 0.337 -0.00521 -0.47 -0.4653 -0.9163 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P18 mock treatment 0.329 -0.0093 -0.75 0.341 -0.00121 -0.11 -0.6071 -0.8021 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P19 mock treatment 0.334 -0.0043 -0.35 0.341 -0.00121 -0.11 -0.3224 -0.8877 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P20 mock treatment 0.337 -0.0013 -0.1 0.339 -0.00321 -0.29 -0.28 -0.9046 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P21 mock treatment 0.326 -0.0123 -0.99 0.332 -0.0102 -0.93 -1.3556 -0.9994 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P22 mock treatment 0.324 -0.0143 -1.15 0.331 -0.0112 -1.02 -1.5337 -0.9981 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P23 positive control 0.088 -0.25 -20.16 0.088 -0.254 -23.07 -30.5687 -0.9977 1017.0011 EnzCoupledColor(1017.0011) TrypanothioneReductase 1017.0011.669 P24 positive control 0.094 -0.244 -19.67 0.093 -0.249 -22.62 -29.9061 -0.9976