ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A01 mock treatment 0.335 0.00247 0.1 0.329 -0.00846 -0.18 -0.0564 -0.2794 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A02 mock treatment 0.303 -0.0295 -1.16 0.322 -0.0155 -0.32 -1.0497 -0.871 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A03 compound treatment 0.303 -0.0295 -1.16 0.307 -0.0305 -0.64 -1.2716 -0.9601 3001896 Bio2_000321 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]24[C@@H](/C=C/C[C@H](C)C(=O)[C@@](C)(O)/C=C/[C@H]4OC(=O)C)[C@H](O)C1=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A04 mock treatment 0.314 -0.0185 -0.73 0.324 -0.0135 -0.28 -0.7143 -0.9145 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A05 compound treatment 0.456 0.123 4.85 0.464 0.127 2.65 5.3052 0.9594 236 Bio2_000322 SC(=S)OC1CC2CC1C3CCCC23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A06 mock treatment 0.299 -0.0335 -1.32 0.309 -0.0285 -0.6 -1.3533 -0.9355 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A07 compound treatment 0.309 -0.0235 -0.93 0.321 -0.0165 -0.34 -0.8977 -0.9094 159 Bio2_000323 COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A08 mock treatment 0.298 -0.0345 -1.36 0.312 -0.0255 -0.53 -1.3367 -0.9166 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A09 compound treatment 0.286 -0.0465 -1.83 0.297 -0.0405 -0.85 -1.8922 -0.9387 2370 Bio2_000324 OCc1ccc(o1)c2nn(Cc3ccccc3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A10 mock treatment 0.299 -0.0335 -1.32 0.315 -0.0225 -0.47 -1.2645 -0.9035 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A11 compound treatment 0.317 -0.0155 -0.61 0.338 5.39E-4 0.01 -0.4237 -0.6939 251 Bio2_000325 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A12 mock treatment 0.323 -0.00953 -0.37 0.329 -0.00846 -0.18 -0.3901 -0.9415 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A13 compound treatment 0.309 -0.0235 -0.93 0.327 -0.0105 -0.22 -0.8089 -0.8509 3001897 Bio2_000326 OC[C@H]1*C[C@@H](O)[C@@H](O)[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A14 mock treatment 0.315 -0.0175 -0.69 0.317 -0.0205 -0.43 -0.79 -0.9738 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A15 compound treatment 0.337 0.00447 0.18 0.33 -0.00746 -0.16 0.014 0.0594 1907766 Bio2_000327 OC[C@H]1*C[C@H](O)[C@@H](O)[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A16 mock treatment 0.298 -0.0345 -1.36 0.307 -0.0305 -0.64 -1.4107 -0.9406 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A17 compound treatment 0.303 -0.0295 -1.16 0.31 -0.0275 -0.57 -1.2273 -0.9474 3103895 Bio2_000328 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A18 mock treatment 0.317 -0.0155 -0.61 0.309 -0.0285 -0.6 -0.8528 -0.9999 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A19 compound treatment 0.327 -0.00553 -0.22 0.329 -0.00846 -0.18 -0.2789 -0.9948 3103896 Bio2_000329 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A20 mock treatment 0.307 -0.0255 -1.0 0.309 -0.0285 -0.6 -1.1308 -0.969 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A21 compound treatment 0.315 -0.0175 -0.69 0.322 -0.0155 -0.32 -0.7161 -0.9406 3001899 Bio2_000330 CCCC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A22 mock treatment 0.319 -0.0135 -0.53 0.325 -0.0125 -0.26 -0.5605 -0.9462 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A23 mock treatment 0.312 -0.0205 -0.81 0.339 0.00154 0.03 -0.5479 -0.6783 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 A24 mock treatment 0.08 -0.253 -9.93 0.078 -0.259 -5.43 -10.86 -0.9597 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B01 mock treatment 0.311 -0.0215 -0.85 0.344 0.00654 0.14 -0.5017 -0.5852 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B02 mock treatment 0.31 -0.0225 -0.89 0.328 -0.00946 -0.2 -0.7663 -0.8443 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B03 compound treatment 0.312 -0.0205 -0.81 0.329 -0.00846 -0.18 -0.6959 -0.8422 440 Bio2_000331 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B04 mock treatment 0.316 -0.0165 -0.65 0.342 0.00454 0.09 -0.3923 -0.5974 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B05 compound treatment 0.309 -0.0235 -0.93 0.305 -0.0325 -0.68 -1.1344 -0.9885 442 Bio2_000332 CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B06 mock treatment 0.301 -0.0315 -1.24 0.332 -0.00546 -0.11 -0.9573 -0.769 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B07 compound treatment 0.318 -0.0145 -0.57 0.322 -0.0155 -0.32 -0.6327 -0.9638 3103897 Bio2_000333 C[C@@H](CC(O)[C@H]1OC2CC[C@@]3(CC[C@H](O3)/C=C/[C@@H](C)[C@@H]4CC(=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CCC5O)O4)C)OC2[C@H](O)C1=C)C6O[C@@]7(CCCCO7)CC[C@H]6C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B08 mock treatment 0.32 -0.0125 -0.49 0.335 -0.00246 -0.05 -0.3847 -0.7768 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B09 compound treatment 0.339 0.00647 0.25 0.348 0.0105 0.22 0.3359 0.9975 3104621 Bio2_000334 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B10 mock treatment 0.322 -0.0105 -0.41 0.322 -0.0155 -0.32 -0.5214 -0.9926 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B11 compound treatment 0.312 -0.0205 -0.81 0.336 -0.00146 -0.03 -0.5923 -0.7334 324 Bio2_000335 Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B12 mock treatment 0.325 -0.00753 -0.3 0.338 5.39E-4 0.01 -0.2013 -0.6797 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B13 compound treatment 0.326 -0.00653 -0.26 0.333 -0.00446 -0.09 -0.2475 -0.9062 3103898 Bio2_000336 CC1OC(OC2CC(O)C3(CO)C4[C@H](O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C6=CC(=O)OC6)C(O)C(O)C1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B14 mock treatment 0.314 -0.0185 -0.73 0.309 -0.0285 -0.6 -0.9362 -0.995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B15 compound treatment 0.278 -0.0545 -2.14 0.294 -0.0435 -0.91 -2.1591 -0.9271 444 Bio2_000337 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc2ccccc2)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B16 mock treatment 0.327 -0.00553 -0.22 0.316 -0.0215 -0.45 -0.4712 -0.9445 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B17 compound treatment 0.352 0.0195 0.77 0.342 0.00454 0.09 0.6086 0.7888 453 Bio2_000338 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B18 mock treatment 0.319 -0.0135 -0.53 0.333 -0.00446 -0.09 -0.4421 -0.8187 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B19 compound treatment 0.368 0.0355 1.39 0.354 0.0165 0.35 1.231 0.8566 1907767 Bio2_000339 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B20 mock treatment 0.327 -0.00553 -0.22 0.322 -0.0155 -0.32 -0.3824 -0.9813 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B21 compound treatment 0.328 -0.00453 -0.18 0.336 -0.00146 -0.03 -0.1475 -0.8166 387 Bio2_000340 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B22 mock treatment 0.315 -0.0175 -0.69 0.325 -0.0125 -0.26 -0.6717 -0.9116 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B23 mock treatment 0.325 -0.00753 -0.3 0.326 -0.0115 -0.24 -0.3789 -0.9946 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 B24 mock treatment 0.077 -0.256 -10.05 0.079 -0.258 -5.41 -10.9286 -0.9578 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C01 mock treatment 0.318 -0.0145 -0.57 0.321 -0.0165 -0.34 -0.6475 -0.9707 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C02 mock treatment 0.32 -0.0125 -0.49 0.326 -0.0115 -0.24 -0.5179 -0.9453 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C03 compound treatment 0.314 -0.0185 -0.73 0.326 -0.0115 -0.24 -0.6847 -0.8928 1907768 Bio2_000341 [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C04 mock treatment 0.336 0.00347 0.14 0.309 -0.0285 -0.6 -0.3246 -0.5312 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C05 compound treatment 0.315 -0.0175 -0.69 0.297 -0.0405 -0.85 -1.086 -0.9948 1907769 Bio2_000342 *C1CCc2cc(O)c(O)cc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C06 mock treatment 0.323 -0.00953 -0.37 0.328 -0.00946 -0.2 -0.4049 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C07 compound treatment 0.358 0.0255 1.0 0.343 0.00554 0.12 0.7902 0.7837 2098 Bio2_000343 CC(C)c1cccc(=O)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C08 mock treatment 0.332 -5.27E-4 -0.02 0.322 -0.0155 -0.32 -0.2434 -0.7509 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C09 compound treatment 0.321 -0.0115 -0.45 0.321 -0.0165 -0.34 -0.564 -0.9908 411 Bio2_000344 [I+]1c2ccccc2-c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C10 mock treatment 0.337 0.00447 0.18 0.342 0.00454 0.09 0.1915 0.9582 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C11 compound treatment 0.317 -0.0155 -0.61 0.316 -0.0215 -0.45 -0.7492 -0.9886 1961 Bio2_000345 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C12 mock treatment 0.333 4.73E-4 0.02 0.334 -0.00346 -0.07 -0.0381 -0.5091 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C13 compound treatment 0.291 -0.0415 -1.63 0.304 -0.0335 -0.7 -1.6497 -0.9286 3103899 Bio2_000346 COc1cccc2C(=O)C3C(C(=C4[C@H](C[C@@](O)(CC4=C3O)C(=O)CO)OC5CC(N)C(O)C(C)O5)O)C(=O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C14 mock treatment 0.326 -0.00653 -0.26 0.328 -0.00946 -0.2 -0.3215 -0.9918 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C15 compound treatment 0.315 -0.0175 -0.69 0.334 -0.00346 -0.07 -0.5385 -0.7771 3000146 Bio2_000347 OC[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C16 mock treatment 0.322 -0.0105 -0.41 0.316 -0.0215 -0.45 -0.6102 -0.9992 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C17 compound treatment 0.368 0.0355 1.39 0.352 0.0145 0.3 1.2014 0.8416 3103900 Bio2_000348 OC(=O)c1ccc(cc1)C2=C3C=CC4=[N+]3[Mn+3]5([N+]6=C7C=CC6=C(c8ccc2n85)c9ccc(cc9)C(=O)O)n%10c(=C4c%11ccc(cc%11)C(=O)O)ccc%10=C7c%12ccc(cc%12)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C18 mock treatment 0.331 -0.00153 -0.06 0.324 -0.0135 -0.28 -0.2416 -0.839 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C19 compound treatment 0.312 -0.0205 -0.81 0.321 -0.0165 -0.34 -0.8143 -0.9279 3002358 Bio2_000349 COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8ccc(Oc(c1OC)c32)cc78)cc6)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C20 mock treatment 0.317 -0.0155 -0.61 0.31 -0.0275 -0.57 -0.838 -0.9995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C21 compound treatment 0.31 -0.0225 -0.89 0.328 -0.00946 -0.2 -0.7663 -0.8443 3002360 Bio2_000350 *[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C22 mock treatment 0.328 -0.00453 -0.18 0.322 -0.0155 -0.32 -0.3546 -0.9604 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C23 mock treatment 0.32 -0.0125 -0.49 0.323 -0.0145 -0.3 -0.5623 -0.9726 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 C24 mock treatment 0.079 -0.254 -9.97 0.078 -0.259 -5.43 -10.8878 -0.9592 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D01 mock treatment 0.337 0.00447 0.18 0.332 -0.00546 -0.11 0.0436 0.2077 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D02 mock treatment 0.314 -0.0185 -0.73 0.327 -0.0105 -0.22 -0.6699 -0.8807 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D03 compound treatment 0.337 0.00447 0.18 0.348 0.0105 0.22 0.2803 0.9937 384 Bio2_000351 O=c1[nH]c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D04 mock treatment 0.32 -0.0125 -0.49 0.309 -0.0285 -0.6 -0.7694 -0.9955 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D05 compound treatment 0.328 -0.00453 -0.18 0.333 -0.00446 -0.09 -0.1919 -0.9546 290 Bio2_000352 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D06 mock treatment 0.333 4.73E-4 0.02 0.334 -0.00346 -0.07 -0.0381 -0.5091 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D07 compound treatment 0.336 0.00347 0.14 0.322 -0.0155 -0.32 -0.1322 -0.3765 455 Bio2_000353 Cc1ccc(cc1)C(=O)Cn2c3CCCCc3sc2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D08 mock treatment 0.341 0.00847 0.33 0.346 0.00854 0.18 0.3619 0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D09 compound treatment 0.333 4.73E-4 0.02 0.333 -0.00446 -0.09 -0.0529 -0.5553 1907770 Bio2_000354 Clc1ccc(cc1)c2nc3sccn3c2/C=N/OCc4ccc(Cl)c(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D10 mock treatment 0.341 0.00847 0.33 0.354 0.0165 0.35 0.4803 0.9998 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D11 compound treatment 0.362 0.0295 1.16 0.368 0.0305 0.64 1.2713 0.9607 347 Bio2_000355 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D12 mock treatment 0.331 -0.00153 -0.06 0.342 0.00454 0.09 0.0247 0.2199 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D13 compound treatment 0.335 0.00247 0.1 0.333 -0.00446 -0.09 0.0027 0.0204 1907771 Bio2_000356 CC1[C@@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D14 mock treatment 0.327 -0.00553 -0.22 0.339 0.00154 0.03 -0.1309 -0.5958 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D15 compound treatment 0.324 -0.00853 -0.34 0.338 5.39E-4 0.01 -0.2291 -0.6829 275745 Bio2_000357 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D16 mock treatment 0.328 -0.00453 -0.18 0.332 -0.00546 -0.11 -0.2067 -0.977 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D17 compound treatment 0.328 -0.00453 -0.18 0.332 -0.00546 -0.11 -0.2067 -0.977 349 Bio2_000358 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D18 mock treatment 0.334 0.00147 0.06 0.34 0.00254 0.05 0.0785 0.9991 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D19 compound treatment 0.272 -0.0605 -2.38 0.278 -0.0595 -1.24 -2.5626 -0.9543 244 Bio2_000359 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D20 mock treatment 0.341 0.00847 0.33 0.34 0.00254 0.05 0.2731 0.8097 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D21 compound treatment 0.33 -0.00253 -0.1 0.337 -4.61E-4 -0.01 -0.0771 -0.7721 3002368 Bio2_000360 CC(C)NC[C@H](O)COc1cccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D22 mock treatment 0.337 0.00447 0.18 0.34 0.00254 0.05 0.1619 0.8814 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D23 mock treatment 0.318 -0.0145 -0.57 0.326 -0.0115 -0.24 -0.5735 -0.9257 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 D24 mock treatment 0.08 -0.253 -9.93 0.079 -0.258 -5.41 -10.8452 -0.9592 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E01 mock treatment 0.321 -0.0115 -0.45 0.336 -0.00146 -0.03 -0.3421 -0.7531 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E02 mock treatment 0.312 -0.0205 -0.81 0.325 -0.0125 -0.26 -0.7551 -0.8903 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E03 compound treatment 0.323 -0.00953 -0.37 0.348 0.0105 0.22 -0.1089 -0.2506 413 Bio2_000361 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E04 mock treatment 0.314 -0.0185 -0.73 0.31 -0.0275 -0.57 -0.9214 -0.9931 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E05 compound treatment 0.312 -0.0205 -0.81 0.32 -0.0175 -0.37 -0.8291 -0.9358 1907772 Bio2_000362 CC(=O)[C@H]1[C@@H](CC2C3CC=C4C[C@@H](O)CCC4(C)C3CCC12C)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E06 mock treatment 0.329 -0.00353 -0.14 0.343 0.00554 0.12 -0.0161 -0.0891 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E07 compound treatment 0.333 4.73E-4 0.02 0.346 0.00854 0.18 0.1395 0.7765 386 Bio2_000363 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E08 mock treatment 0.34 0.00747 0.29 0.35 0.0125 0.26 0.3933 0.9984 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E09 compound treatment 0.332 -5.27E-4 -0.02 0.356 0.0185 0.39 0.2597 0.6684 2080384 Bio2_000364 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E10 mock treatment 0.348 0.0155 0.61 0.354 0.0165 0.35 0.6749 0.9643 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E11 compound treatment 0.595 0.262 10.32 0.583 0.246 5.14 10.9305 0.9481 415 Bio2_000365 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E12 mock treatment 0.348 0.0155 0.61 0.34 0.00254 0.05 0.4678 0.766 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E13 compound treatment 0.337 0.00447 0.18 0.338 5.39E-4 0.01 0.1323 0.7509 3002452 Bio2_000366 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E14 mock treatment 0.337 0.00447 0.18 0.337 -4.61E-4 -0.01 0.1175 0.6673 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E15 compound treatment 0.344 0.0115 0.45 0.342 0.00454 0.09 0.3861 0.8376 3104393 Bio2_000367 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E16 mock treatment 0.34 0.00747 0.29 0.344 0.00654 0.14 0.3045 0.9395 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E17 compound treatment 0.334 0.00147 0.06 0.338 5.39E-4 0.01 0.0489 0.8293 3103903 Bio2_000368 Cc1ccc(cc1)C2=CCc3cc(C)cc(C)c3C2=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E18 mock treatment 0.334 0.00147 0.06 0.339 0.00154 0.03 0.0637 0.9617 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E19 compound treatment 0.279 -0.0535 -2.1 0.295 -0.0425 -0.89 -2.1165 -0.9265 576 Bio2_000369 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCSC(=N)N)c4ccccc34)c5ccccc15 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E20 mock treatment 0.338 0.00547 0.22 0.344 0.00654 0.14 0.2489 0.9761 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E21 compound treatment 0.337 0.00447 0.18 0.344 0.00654 0.14 0.2211 0.9923 162 Bio2_000370 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E22 mock treatment 0.334 0.00147 0.06 0.339 0.00154 0.03 0.0637 0.9617 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E23 mock treatment 0.317 -0.0155 -0.61 0.329 -0.00846 -0.18 -0.5569 -0.8761 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 E24 mock treatment 0.081 -0.252 -9.89 0.081 -0.256 -5.37 -10.7878 -0.9588 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F01 mock treatment 0.335 0.00247 0.1 0.328 -0.00946 -0.2 -0.0712 -0.323 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F02 mock treatment 0.314 -0.0185 -0.73 0.325 -0.0125 -0.26 -0.6995 -0.904 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F03 compound treatment 0.34 0.00747 0.29 0.333 -0.00446 -0.09 0.1418 0.4598 3002455 Bio2_000371 *[C@H]1O[C@H]([C@H](O)[C@@H]1NC(=O)C(N)Cc2ccccc2)n3cnc4c(ncnc34)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F04 mock treatment 0.312 -0.0205 -0.81 0.314 -0.0235 -0.49 -0.9178 -0.9716 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F05 compound treatment 0.338 0.00547 0.22 0.348 0.0105 0.22 0.3081 0.9999 1907773 Bio2_000372 NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc4OCOc4c3)c5ccccn5 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F06 mock treatment 0.318 -0.0145 -0.57 0.346 0.00854 0.18 -0.2775 -0.4637 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F07 compound treatment 0.399 0.0665 2.61 0.418 0.0805 1.69 3.0398 0.9775 1000035 Bio2_000373 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F08 mock treatment 0.335 0.00247 0.1 0.358 0.0205 0.43 0.3727 0.8457 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F09 compound treatment 0.438 0.105 4.15 0.449 0.112 2.33 4.5828 0.963 353 Bio2_000374 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F10 mock treatment 0.343 0.0105 0.41 0.356 0.0185 0.39 0.5655 0.9996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F11 compound treatment 0.319 -0.0135 -0.53 0.297 -0.0405 -0.85 -0.9748 -0.9749 3104890 Bio2_000375 CO[C@@H]1CC(CC(C)[C@@H]2CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F12 mock treatment 0.306 -0.0265 -1.04 0.347 0.00954 0.2 -0.5964 -0.5616 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F13 compound treatment 0.34 0.00747 0.29 0.36 0.0225 0.47 0.5413 0.9741 1907774 Bio2_000376 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F14 mock treatment 0.341 0.00847 0.33 0.348 0.0105 0.22 0.3915 0.9799 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F15 compound treatment 0.32 -0.0125 -0.49 0.332 -0.00546 -0.11 -0.4291 -0.8486 285 Bio2_000377 O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F16 mock treatment 0.342 0.00947 0.37 0.315 -0.0225 -0.47 -0.069 -0.115 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F17 compound treatment 0.319 -0.0135 -0.53 0.331 -0.00646 -0.14 -0.4717 -0.8595 151 Bio2_000378 CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F18 mock treatment 0.329 -0.00353 -0.14 0.344 0.00654 0.14 -0.0013 -0.0067 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F19 compound treatment 0.319 -0.0135 -0.53 0.33 -0.00746 -0.16 -0.4865 -0.8776 291 Bio2_000379 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F20 mock treatment 0.335 0.00247 0.1 0.315 -0.0225 -0.47 -0.2636 -0.5492 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F21 compound treatment 0.341 0.00847 0.33 0.378 0.0405 0.85 0.8354 0.9166 320 Bio2_000380 CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F22 mock treatment 0.33 -0.00253 -0.1 0.332 -0.00546 -0.11 -0.1511 -0.9976 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F23 mock treatment 0.321 -0.0115 -0.45 0.327 -0.0105 -0.22 -0.4753 -0.9443 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 F24 mock treatment 0.081 -0.252 -9.89 0.081 -0.256 -5.37 -10.7878 -0.9588 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G01 mock treatment 0.333 4.73E-4 0.02 0.336 -0.00146 -0.03 -0.0085 -0.2367 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G02 mock treatment 0.311 -0.0215 -0.85 0.326 -0.0115 -0.24 -0.7681 -0.8731 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G03 compound treatment 0.369 0.0365 1.43 0.369 0.0315 0.66 1.4807 0.938 152 Bio2_000381 Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G04 mock treatment 0.333 4.73E-4 0.02 0.333 -0.00446 -0.09 -0.0529 -0.5553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G05 compound treatment 0.466 0.133 5.25 0.462 0.125 2.61 5.5536 0.9478 1298 Bio2_000382 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G06 mock treatment 0.318 -0.0145 -0.57 0.323 -0.0145 -0.3 -0.6179 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G07 compound treatment 0.319 -0.0135 -0.53 0.328 -0.00946 -0.2 -0.5161 -0.9094 414 Bio2_000383 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G08 mock treatment 0.323 -0.00953 -0.37 0.344 0.00654 0.14 -0.1681 -0.4215 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G09 compound treatment 0.286 -0.0465 -1.83 0.304 -0.0335 -0.7 -1.7887 -0.9132 607 Bio2_000384 Brc1ccc(/C=C/CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G10 mock treatment 0.343 0.0105 0.41 0.347 0.00954 0.2 0.4323 0.9447 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G11 compound treatment 0.331 -0.00153 -0.06 0.329 -0.00846 -0.18 -0.1677 -0.8967 3002468 Bio2_000385 NCCNOc1cccc2cnccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G12 mock treatment 0.343 0.0105 0.41 0.341 0.00354 0.07 0.3435 0.8211 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G13 compound treatment 0.327 -0.00553 -0.22 0.334 -0.00346 -0.07 -0.2049 -0.8944 610 Bio2_000386 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G14 mock treatment 0.329 -0.00353 -0.14 0.333 -0.00446 -0.09 -0.1641 -0.9814 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G15 compound treatment 0.322 -0.0105 -0.41 0.33 -0.00746 -0.16 -0.4031 -0.9112 609 Bio2_000387 NC(=N)NCCNS(=O)(=O)c1cccc2cnccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G16 mock treatment 0.331 -0.00153 -0.06 0.333 -0.00446 -0.09 -0.1085 -0.9772 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G17 compound treatment 0.204 -0.129 -5.05 0.199 -0.138 -2.9 -5.6221 -0.9651 611 Bio2_000388 COCc1cc(O)c(O)c(O)c1c2c(O)c(O)c(O)cc2COC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G18 mock treatment 0.321 -0.0115 -0.45 0.333 -0.00446 -0.09 -0.3865 -0.8352 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G19 compound treatment 0.332 -5.27E-4 -0.02 0.326 -0.0115 -0.24 -0.1842 -0.7654 465 Bio2_000389 NCCc1c[nH]cn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G20 mock treatment 0.334 0.00147 0.06 0.335 -0.00246 -0.05 0.0045 0.0585 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G21 compound treatment 0.34 0.00747 0.29 0.34 0.00254 0.05 0.2453 0.8217 239 Bio2_000390 CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(=O)C)OCOC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G22 mock treatment 0.324 -0.00853 -0.34 0.33 -0.00746 -0.16 -0.3475 -0.9395 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G23 mock treatment 0.313 -0.0195 -0.77 0.32 -0.0175 -0.37 -0.8013 -0.9424 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 G24 mock treatment 0.081 -0.252 -9.89 0.081 -0.256 -5.37 -10.7878 -0.9588 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H01 mock treatment 0.336 0.00347 0.14 0.35 0.0125 0.26 0.2821 0.9537 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H02 mock treatment 0.318 -0.0145 -0.57 0.327 -0.0105 -0.22 -0.5587 -0.9133 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H03 compound treatment 0.337 0.00447 0.18 0.353 0.0155 0.33 0.3543 0.9584 3104891 Bio2_000391 CC(=O)OCOC(P(=O)OCOC(=O)C)c1cc(ccc1Oc2ccc(Br)cc2)[N+](=O)[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H04 mock treatment 0.316 -0.0165 -0.65 0.318 -0.0195 -0.41 -0.7474 -0.9747 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H05 compound treatment 0.352 0.0195 0.77 0.362 0.0245 0.51 0.9045 0.9811 1907775 Bio2_000392 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H06 mock treatment 0.321 -0.0115 -0.45 0.342 0.00454 0.09 -0.2533 -0.547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H07 compound treatment 0.33 -0.00253 -0.1 0.355 0.0175 0.37 0.1893 0.4978 457 Bio2_000393 Oc1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H08 mock treatment 0.329 -0.00353 -0.14 0.348 0.0105 0.22 0.0579 0.2222 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H09 compound treatment 0.346 0.0135 0.53 0.352 0.0145 0.3 0.5897 0.9653 1000586 Bio2_000394 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H10 mock treatment 0.346 0.0135 0.53 0.361 0.0235 0.49 0.7229 0.9993 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H11 compound treatment 0.348 0.0155 0.61 0.346 0.00854 0.18 0.5565 0.8777 3104892 Bio2_000395 O=C/1Nc2ccccc2\C1=C/3\Nc4ccccc4C3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H12 mock treatment 0.324 -0.00853 -0.34 0.344 0.00654 0.14 -0.1403 -0.3875 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H13 compound treatment 0.333 4.73E-4 0.02 0.344 0.00654 0.14 0.1099 0.7959 429 Bio2_000396 NCCc1c[nH]c2ccc(O)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H14 mock treatment 0.342 0.00947 0.37 0.345 0.00754 0.16 0.3749 0.9269 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H15 compound treatment 0.331 -0.00153 -0.06 0.308 -0.0295 -0.62 -0.4784 -0.7723 2269 Bio2_000397 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H16 mock treatment 0.339 0.00647 0.25 0.34 0.00254 0.05 0.2175 0.8367 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H17 compound treatment 0.339 0.00647 0.25 0.342 0.00454 0.09 0.2471 0.9097 2301 Bio2_000398 O=C1CCc2c(O1)ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H18 mock treatment 0.333 4.73E-4 0.02 0.336 -0.00146 -0.03 -0.0085 -0.2367 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H19 compound treatment 0.334 0.00147 0.06 0.339 0.00154 0.03 0.0637 0.9617 650 Bio2_000399 CC(C)(C)n1nc(c2ccc(Cl)cc2)c3c(N)ncnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H20 mock treatment 0.334 0.00147 0.06 0.342 0.00454 0.09 0.1081 0.9718 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H21 compound treatment 0.313 -0.0195 -0.77 0.319 -0.0185 -0.39 -0.8161 -0.9495 648 Bio2_000400 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H22 mock treatment 0.335 0.00247 0.1 0.332 -0.00546 -0.11 -0.0121 -0.0803 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H23 mock treatment 0.319 -0.0135 -0.53 0.325 -0.0125 -0.26 -0.5605 -0.9462 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 H24 mock treatment 0.083 -0.25 -9.81 0.082 -0.255 -5.35 -10.7174 -0.9592 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I01 mock treatment 0.34 0.00747 0.29 0.324 -0.0135 -0.28 0.0086 0.0211 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I02 mock treatment 0.331 -0.00153 -0.06 0.334 -0.00346 -0.07 -0.0937 -0.9957 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I03 compound treatment 0.365 0.0325 1.28 0.371 0.0335 0.7 1.3991 0.9603 369 Bio2_000401 CCOc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5cc(ccc5[nH]4)N6CCN(C)CC6 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I04 mock treatment 0.321 -0.0115 -0.45 0.316 -0.0215 -0.45 -0.638 -1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I05 compound treatment 0.336 0.00347 0.14 0.344 0.00654 0.14 0.1933 1.0 1001953 Bio2_000402 C/C=C/1\C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I06 mock treatment 0.347 0.0145 0.57 0.35 0.0125 0.26 0.5879 0.9382 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I07 compound treatment 0.35 0.0175 0.69 0.349 0.0115 0.24 0.6565 0.9016 1907776 Bio2_000403 CC(C)[C@H](O)CCC(C)C1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I08 mock treatment 0.341 0.00847 0.33 0.366 0.0285 0.6 0.6579 0.962 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I09 compound treatment 0.34 0.00747 0.29 0.342 0.00454 0.09 0.2749 0.8903 3002553 Bio2_000404 C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I10 mock treatment 0.358 0.0255 1.0 0.363 0.0255 0.53 1.0861 0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I11 compound treatment 0.353 0.0205 0.8 0.359 0.0215 0.45 0.8879 0.9624 2797 Bio2_000405 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I12 mock treatment 0.347 0.0145 0.57 0.344 0.00654 0.14 0.4991 0.8528 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I13 compound treatment 0.333 4.73E-4 0.02 0.328 -0.00946 -0.2 -0.1268 -0.6379 3002555 Bio2_000406 *CC[C@@H](C)C[C@H](C)C[C@H](C)C(=O)/C=C(\O)/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]2CC[C@](C)(O2)[C@@H](C)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I14 mock treatment 0.339 0.00647 0.25 0.344 0.00654 0.14 0.2767 0.9577 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I15 compound treatment 0.329 -0.00353 -0.14 0.339 0.00154 0.03 -0.0753 -0.5288 1505 Bio2_000407 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I16 mock treatment 0.333 4.73E-4 0.02 0.341 0.00354 0.07 0.0655 0.858 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I17 compound treatment 0.301 -0.0315 -1.24 0.305 -0.0325 -0.68 -1.3568 -0.9599 1054783 Bio2_000408 OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I18 mock treatment 0.337 0.00447 0.18 0.329 -0.00846 -0.18 -8.0E-4 -0.0034 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I19 compound treatment 0.282 -0.0505 -1.99 0.296 -0.0415 -0.87 -2.0183 -0.931 422 Bio2_000409 Oc1cccc2C(=O)C=CC(=O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I20 mock treatment 0.339 0.00647 0.25 0.341 0.00354 0.07 0.2323 0.8765 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I21 compound treatment 0.337 0.00447 0.18 0.321 -0.0165 -0.34 -0.1192 -0.3082 1907777 Bio2_000410 COC(=O)[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I22 mock treatment 0.326 -0.00653 -0.26 0.342 0.00454 0.09 -0.1143 -0.4177 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I23 mock treatment 0.328 -0.00453 -0.18 0.33 -0.00746 -0.16 -0.2363 -0.9979 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 I24 mock treatment 0.084 -0.249 -9.77 0.083 -0.254 -5.32 -10.6748 -0.9593 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J01 mock treatment 0.338 0.00547 0.22 0.334 -0.00346 -0.07 0.1009 0.4446 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J02 mock treatment 0.329 -0.00353 -0.14 0.333 -0.00446 -0.09 -0.1641 -0.9814 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J03 compound treatment 0.325 -0.00753 -0.3 0.335 -0.00246 -0.05 -0.2457 -0.8179 837968 Bio2_000411 Nc1ncnc2n(cnc12)C3CCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J04 mock treatment 0.329 -0.00353 -0.14 0.329 -0.00846 -0.18 -0.2233 -0.9927 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J05 compound treatment 0.323 -0.00953 -0.37 0.328 -0.00946 -0.2 -0.4049 -0.9556 790507 Bio2_000412 OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J06 mock treatment 0.322 -0.0105 -0.41 0.327 -0.0105 -0.22 -0.4475 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J07 compound treatment 0.342 0.00947 0.37 0.334 -0.00346 -0.07 0.2122 0.5591 3104896 Bio2_000413 CN[C@@H]1C[C@@]2(C)O[C@@H]([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J08 mock treatment 0.333 4.73E-4 0.02 0.349 0.0115 0.24 0.1839 0.7593 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J09 compound treatment 0.314 -0.0185 -0.73 0.319 -0.0185 -0.39 -0.7883 -0.956 197 Bio2_000414 O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J10 mock treatment 0.341 0.00847 0.33 0.357 0.0195 0.41 0.5247 0.9948 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J11 compound treatment 0.292 -0.0405 -1.59 0.297 -0.0405 -0.85 -1.7254 -0.9562 368 Bio2_000415 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J12 mock treatment 0.325 -0.00753 -0.3 0.352 0.0145 0.3 0.0059 0.0138 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J13 compound treatment 0.348 0.0155 0.61 0.35 0.0125 0.26 0.6157 0.9293 1000045 Bio2_000416 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J14 mock treatment 0.348 0.0155 0.61 0.322 -0.0155 -0.32 0.2014 0.2923 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J15 compound treatment 0.343 0.0105 0.41 0.347 0.00954 0.2 0.4323 0.9447 658 Bio2_000417 Clc1cc(Cl)cc(/C=C(\C#N)/c2cccnc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J16 mock treatment 0.342 0.00947 0.37 0.341 0.00354 0.07 0.3157 0.8314 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J17 compound treatment 0.329 -0.00353 -0.14 0.338 5.39E-4 0.01 -0.0901 -0.6474 370 Bio2_000418 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J18 mock treatment 0.338 0.00547 0.22 0.342 0.00454 0.09 0.2193 0.9324 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J19 compound treatment 0.345 0.0125 0.49 0.321 -0.0165 -0.34 0.1032 0.1722 358 Bio2_000419 N[C@@H](CCCNC(=S)N)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J20 mock treatment 0.348 0.0155 0.61 0.35 0.0125 0.26 0.6157 0.9293 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J21 compound treatment 0.336 0.00347 0.14 0.371 0.0335 0.7 0.5928 0.8291 572 Bio2_000420 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J22 mock treatment 0.34 0.00747 0.29 0.343 0.00554 0.12 0.2897 0.9173 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J23 mock treatment 0.324 -0.00853 -0.34 0.322 -0.0155 -0.32 -0.4658 -0.9998 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 J24 mock treatment 0.085 -0.248 -9.73 0.083 -0.254 -5.32 -10.647 -0.9597 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K01 mock treatment 0.344 0.0115 0.45 0.346 0.00854 0.18 0.4453 0.9178 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K02 mock treatment 0.332 -5.27E-4 -0.02 0.332 -0.00546 -0.11 -0.0955 -0.8219 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K03 compound treatment 0.406 0.0735 2.89 0.403 0.0655 1.37 3.0125 0.942 3419827 Bio2_000421 CN(C(Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K04 mock treatment 0.329 -0.00353 -0.14 0.326 -0.0115 -0.24 -0.2676 -0.9661 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K05 compound treatment 0.342 0.00947 0.37 0.354 0.0165 0.35 0.5081 0.9993 1907778 Bio2_000422 *[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K06 mock treatment 0.348 0.0155 0.61 0.328 -0.00946 -0.2 0.2902 0.4536 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K07 compound treatment 0.354 0.0215 0.84 0.345 0.00754 0.16 0.7085 0.825 3104897 Bio2_000423 CCC(C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NC[C@@H](N)CS 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K08 mock treatment 0.358 0.0255 1.0 0.36 0.0225 0.47 1.0417 0.941 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K09 compound treatment 0.339 0.00647 0.25 0.345 0.00754 0.16 0.2915 0.9736 1908 Bio2_000424 [O-][n+]1onc(c1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K10 mock treatment 0.344 0.0115 0.45 0.357 0.0195 0.41 0.6081 0.9988 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K11 compound treatment 0.325 -0.00753 -0.3 0.336 -0.00146 -0.03 -0.2309 -0.776 3001166 Bio2_000425 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K12 mock treatment 0.337 0.00447 0.18 0.348 0.0105 0.22 0.2803 0.9937 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K13 compound treatment 0.284 -0.0485 -1.91 0.291 -0.0465 -0.97 -2.0366 -0.9511 284 Bio2_000426 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K14 mock treatment 0.345 0.0125 0.49 0.345 0.00754 0.16 0.4583 0.8897 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K15 compound treatment 0.341 0.00847 0.33 0.345 0.00754 0.16 0.3471 0.9417 1907779 Bio2_000427 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K16 mock treatment 0.337 0.00447 0.18 0.351 0.0135 0.28 0.3247 0.9737 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K17 compound treatment 0.316 -0.0165 -0.65 0.322 -0.0155 -0.32 -0.6883 -0.9481 3104898 Bio2_000428 CC(C)C[C@H](NC(=O)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K18 mock treatment 0.339 0.00647 0.25 0.342 0.00454 0.09 0.2471 0.9097 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K19 compound treatment 0.119 -0.214 -8.4 0.122 -0.215 -4.51 -9.1247 -0.9575 1954 Bio2_000429 Cc1ccc(cc1)S(=O)(=O)/C=C/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K20 mock treatment 0.34 0.00747 0.29 0.352 0.0145 0.3 0.4229 0.9998 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K21 compound treatment 1.484 1.15 45.27 1.471 1.13 23.72 48.7864 0.9545 1002387 Bio2_000430 Oc1ccc(C=C(C#N)C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K22 mock treatment 0.336 0.00347 0.14 0.343 0.00554 0.12 0.1785 0.9967 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K23 mock treatment 0.321 -0.0115 -0.45 0.321 -0.0165 -0.34 -0.564 -0.9908 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 K24 mock treatment 0.086 -0.247 -9.69 0.085 -0.252 -5.28 -10.5896 -0.9593 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L01 mock treatment 0.342 0.00947 0.37 0.352 0.0145 0.3 0.4785 0.995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L02 mock treatment 0.323 -0.00953 -0.37 0.32 -0.0175 -0.37 -0.5232 -0.9999 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L03 compound treatment 0.586 0.253 9.97 0.577 0.24 5.01 10.5915 0.9494 566 Bio2_000431 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L04 mock treatment 0.336 0.00347 0.14 0.337 -4.61E-4 -0.01 0.0897 0.6555 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L05 compound treatment 0.333 4.73E-4 0.02 0.329 -0.00846 -0.18 -0.112 -0.6294 1907780 Bio2_000432 COC1=CC(=O)OC(C1)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L06 mock treatment 0.326 -0.00653 -0.26 0.326 -0.0115 -0.24 -0.3511 -0.9994 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L07 compound treatment 0.324 -0.00853 -0.34 0.329 -0.00846 -0.18 -0.3623 -0.9555 431 Bio2_000433 C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L08 mock treatment 0.339 0.00647 0.25 0.351 0.0135 0.28 0.3803 0.9986 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L09 compound treatment 0.361 0.0285 1.12 0.362 0.0245 0.51 1.1547 0.9375 199 Bio2_000434 C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L10 mock treatment 0.343 0.0105 0.41 0.328 -0.00946 -0.2 0.1512 0.3309 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L11 compound treatment 0.309 -0.0235 -0.93 0.311 -0.0265 -0.55 -1.0456 -0.9699 437 Bio2_000435 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L12 mock treatment 0.361 0.0285 1.12 0.361 0.0235 0.49 1.1399 0.932 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L13 compound treatment 0.359 0.0265 1.04 0.369 0.0315 0.66 1.2027 0.9758 3001422 Bio2_000436 *C1OC(OC2OC(CC(O)C3OC(C(O)C3O)n4ccc(=O)[nH]c4=O)C(O)C(O)C2NC(=O)/C=C\*C(C)C)C(NC(=O)C)C(O)C1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L14 mock treatment 0.353 0.0205 0.8 0.344 0.00654 0.14 0.6659 0.8156 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L15 compound treatment 0.368 0.0355 1.39 0.361 0.0235 0.49 1.3345 0.9022 203 Bio2_000437 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L16 mock treatment 0.341 0.00847 0.33 0.338 5.39E-4 0.01 0.2435 0.7306 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L17 compound treatment 0.463 0.13 5.13 0.462 0.125 2.61 5.4702 0.9507 553 Bio2_000438 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L18 mock treatment 0.338 0.00547 0.22 0.349 0.0115 0.24 0.3229 0.9983 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L19 compound treatment 0.343 0.0105 0.41 0.348 0.0105 0.22 0.4471 0.9572 568 Bio2_000439 COc1ccc(C=C(C#N)C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L20 mock treatment 0.34 0.00747 0.29 0.322 -0.0155 -0.32 -0.021 -0.0481 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L21 compound treatment 0.35 0.0175 0.69 0.34 0.00254 0.05 0.5234 0.7595 5 Bio2_000440 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L22 mock treatment 0.34 0.00747 0.29 0.32 -0.0175 -0.37 -0.0506 -0.1079 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L23 mock treatment 0.325 -0.00753 -0.3 0.328 -0.00946 -0.2 -0.3493 -0.9809 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 L24 mock treatment 0.087 -0.246 -9.65 0.087 -0.25 -5.24 -10.5322 -0.9588 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M01 mock treatment 0.329 -0.00353 -0.14 0.345 0.00754 0.16 0.0135 0.0643 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M02 mock treatment 0.333 4.73E-4 0.02 0.341 0.00354 0.07 0.0655 0.858 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M03 compound treatment 0.336 0.00347 0.14 0.338 5.39E-4 0.01 0.1045 0.7629 423 Bio2_000441 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M04 mock treatment 0.328 -0.00453 -0.18 0.344 0.00654 0.14 -0.0291 -0.1296 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M05 compound treatment 0.346 0.0135 0.53 0.35 0.0125 0.26 0.5601 0.9475 321 Bio2_000442 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M06 mock treatment 0.326 -0.00653 -0.26 0.331 -0.00646 -0.14 -0.2771 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M07 compound treatment 0.346 0.0135 0.53 0.348 0.0105 0.22 0.5305 0.9246 243 Bio2_000443 O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M08 mock treatment 0.341 0.00847 0.33 0.342 0.00454 0.09 0.3027 0.8739 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M09 compound treatment 0.333 4.73E-4 0.02 0.344 0.00654 0.14 0.1099 0.7959 1059329 Bio2_000444 Nc1ncnc2n(cc(I)c12)C3OC(CO)C(O)C3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M10 mock treatment 0.345 0.0125 0.49 0.35 0.0125 0.26 0.5323 0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M11 compound treatment 0.378 0.0455 1.79 0.386 0.0485 1.02 1.9825 0.9641 3104900 Bio2_000445 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M12 mock treatment 0.338 0.00547 0.22 0.363 0.0255 0.53 0.5301 0.92 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M13 compound treatment 0.351 0.0185 0.73 0.345 0.00754 0.16 0.6251 0.8411 192 Bio2_000446 CCCCC(C)/C=C(\C)/C=C(\C)/C(=O)NC1=CC(O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)C3OC3C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M14 mock treatment 0.339 0.00647 0.25 0.354 0.0165 0.35 0.4247 0.9886 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M15 compound treatment 0.361 0.0285 1.12 0.352 0.0145 0.3 1.0067 0.8678 907409 Bio2_000447 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M16 mock treatment 0.343 0.0105 0.41 0.34 0.00254 0.05 0.3287 0.7918 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M17 compound treatment 0.408 0.0755 2.97 0.41 0.0725 1.52 3.1717 0.9515 419 Bio2_000448 CC1=NN(C(=O)C1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M18 mock treatment 0.325 -0.00753 -0.3 0.355 0.0175 0.37 0.0503 0.1066 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M19 compound treatment 0.323 -0.00953 -0.37 0.349 0.0115 0.24 -0.0941 -0.2112 3002144 Bio2_000449 CN1C(=O)[C@@]23CC4=CC=C[C@H](O)[C@H]4N3C(=O)[C@@]1(CO)[S+](C)S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M20 mock treatment 0.348 0.0155 0.61 0.327 -0.0105 -0.22 0.2754 0.4259 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M21 compound treatment 0.336 0.00347 0.14 0.33 -0.00746 -0.16 -0.0138 -0.0667 638 Bio2_000450 C/C(=C(\C#N)/C(=O)Nc1cc(Br)ccc1Br)/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M22 mock treatment 0.333 4.73E-4 0.02 0.348 0.0105 0.22 0.1691 0.764 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M23 mock treatment 0.328 -0.00453 -0.18 0.326 -0.0115 -0.24 -0.2954 -0.9892 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 M24 mock treatment 0.089 -0.244 -9.57 0.087 -0.25 -5.24 -10.4766 -0.9598 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N01 mock treatment 0.331 -0.00153 -0.06 0.332 -0.00546 -0.11 -0.1233 -0.9549 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N02 mock treatment 0.338 0.00547 0.22 0.343 0.00554 0.12 0.2341 0.9579 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N03 compound treatment 0.278 -0.0545 -2.14 0.269 -0.0685 -1.43 -2.529 -0.9808 3104901 Bio2_000451 CCCc1cc(OC)ccc1C.CC12CCCCC2CCC1NCCCCCCN3C(=O)C=CC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N04 mock treatment 0.339 0.00647 0.25 0.336 -0.00146 -0.03 0.1583 0.6177 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N05 compound treatment 0.368 0.0355 1.39 0.362 0.0245 0.51 1.3493 0.9079 325 Bio2_000452 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N06 mock treatment 0.336 0.00347 0.14 0.334 -0.00346 -0.07 0.0453 0.2934 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N07 compound treatment 0.328 -0.00453 -0.18 0.329 -0.00846 -0.18 -0.2511 -1.0 2430 Bio2_000453 CC(C)C1NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N08 mock treatment 0.342 0.00947 0.37 0.348 0.0105 0.22 0.4193 0.9687 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N09 compound treatment 0.386 0.0535 2.1 0.391 0.0535 1.12 2.2789 0.9566 3002149 Bio2_000454 *[C@@H]1[C@H]([C@@H]2CN(C[C@](O)(CC)C2)CCc3c1[nH]c4ccccc34)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](O)[C@]7(O)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N10 mock treatment 0.335 0.00247 0.1 0.346 0.00854 0.18 0.1951 0.9591 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N11 compound treatment 0.353 0.0205 0.8 0.358 0.0205 0.43 0.8731 0.9568 3002210 Bio2_000455 *CCCCCCNOc1cccc2c(Cl)cccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N12 mock treatment 0.356 0.0235 0.92 0.355 0.0175 0.37 0.9121 0.9184 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N13 compound treatment 0.4 0.0675 2.65 0.382 0.0445 0.93 2.5349 0.9015 293 Bio2_000456 COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)C4CCC5=O)OC(=O)C)[C@]1(C)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N14 mock treatment 0.352 0.0195 0.77 0.345 0.00754 0.16 0.6529 0.8353 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N15 compound treatment 0.346 0.0135 0.53 0.331 -0.00646 -0.14 0.279 0.5103 677 Bio2_000457 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N16 mock treatment 0.333 4.73E-4 0.02 0.327 -0.0105 -0.22 -0.1416 -0.6447 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N17 compound treatment 0.343 0.0105 0.41 0.341 0.00354 0.07 0.3435 0.8211 3000363 Bio2_000458 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N18 mock treatment 0.341 0.00847 0.33 0.329 -0.00846 -0.18 0.1104 0.2926 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N19 compound treatment 0.34 0.00747 0.29 0.344 0.00654 0.14 0.3045 0.9395 207 Bio2_000459 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)/C=C/S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N20 mock treatment 0.348 0.0155 0.61 0.329 -0.00846 -0.18 0.305 0.4813 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N21 compound treatment 0.342 0.00947 0.37 0.326 -0.0115 -0.24 0.0938 0.2117 352 Bio2_000460 CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N22 mock treatment 0.339 0.00647 0.25 0.324 -0.0135 -0.28 -0.0192 -0.0506 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N23 mock treatment 0.33 -0.00253 -0.1 0.33 -0.00746 -0.16 -0.1807 -0.9762 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 N24 mock treatment 0.089 -0.244 -9.57 0.088 -0.249 -5.22 -10.4618 -0.9593 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O01 mock treatment 0.326 -0.00653 -0.26 0.341 0.00354 0.07 -0.1291 -0.4833 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O02 mock treatment 0.336 0.00347 0.14 0.341 0.00354 0.07 0.1489 0.9587 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O03 compound treatment 0.337 0.00447 0.18 0.343 0.00554 0.12 0.2063 0.9795 3002219 Bio2_000461 *CCC(NC(=O)c1ccc(cc1)N(C)Cc2cnc3nc(N)nc(N)c3n2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O04 mock treatment 0.353 0.0205 0.8 0.343 0.00554 0.12 0.6512 0.8007 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O05 compound treatment 0.324 -0.00853 -0.34 0.334 -0.00346 -0.07 -0.2883 -0.8405 1001921 Bio2_000462 Clc1ccc(cn1)C2CC3CCC2N3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O06 mock treatment 0.336 0.00347 0.14 0.346 0.00854 0.18 0.2229 0.9912 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O07 compound treatment 0.38 0.0475 1.87 0.396 0.0585 1.23 2.1861 0.9791 381 Bio2_000463 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3CCCC(=O)O3)[C@@H]12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O08 mock treatment 0.353 0.0205 0.8 0.367 0.0295 0.62 1.0063 0.9915 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O09 compound treatment 0.369 0.0365 1.43 0.365 0.0275 0.58 1.4215 0.9198 1000019 Bio2_000464 CO[C@@]12[C@H]3N[C@H]3CN2C4=C([C@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O10 mock treatment 0.359 0.0265 1.04 0.352 0.0145 0.3 0.9511 0.8771 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O11 compound treatment 0.351 0.0185 0.73 0.353 0.0155 0.33 0.7435 0.9343 281 Bio2_000465 Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O12 mock treatment 0.352 0.0195 0.77 0.358 0.0205 0.43 0.8453 0.9627 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O13 compound treatment 0.349 0.0165 0.65 0.357 0.0195 0.41 0.7471 0.9754 3002225 Bio2_000466 Clc1cccc2c(cccc12)S(=O)(=O)N3CC*CCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O14 mock treatment 0.349 0.0165 0.65 0.338 5.39E-4 0.01 0.466 0.7193 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O15 compound treatment 0.333 4.73E-4 0.02 0.326 -0.0115 -0.24 -0.1564 -0.6503 438 Bio2_000467 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(O)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O16 mock treatment 0.345 0.0125 0.49 0.33 -0.00746 -0.16 0.2364 0.4593 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O17 compound treatment 0.441 0.108 4.26 0.445 0.108 2.25 4.607 0.9554 656 Bio2_000468 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O18 mock treatment 0.342 0.00947 0.37 0.338 5.39E-4 0.01 0.2713 0.7282 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O19 compound treatment 0.336 0.00347 0.14 0.345 0.00754 0.16 0.2081 0.9974 3104902 Bio2_000469 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)C/C=C(\C)/OO)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O20 mock treatment 0.339 0.00647 0.25 0.324 -0.0135 -0.28 -0.0192 -0.0506 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O21 compound treatment 0.349 0.0165 0.65 0.348 0.0105 0.22 0.6139 0.8973 1907781 Bio2_000470 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)C3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O22 mock treatment 0.335 0.00247 0.1 0.327 -0.0105 -0.22 -0.086 -0.3592 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O23 mock treatment 0.328 -0.00453 -0.18 0.326 -0.0115 -0.24 -0.2954 -0.9892 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 O24 mock treatment 0.092 -0.241 -9.46 0.09 -0.247 -5.18 -10.3488 -0.9598 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P01 positive control 0.346 0.0135 0.53 0.344 0.00654 0.14 0.4713 0.8615 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P02 positive control 0.344 0.0115 0.45 0.368 0.0305 0.64 0.7709 0.9855 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P03 mock treatment 0.354 0.0215 0.84 0.352 0.0145 0.3 0.8121 0.905 201 Bio2_000471 COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P04 positive control 0.361 0.0285 1.12 0.379 0.0415 0.87 1.4063 0.9922 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P05 mock treatment 0.394 0.0615 2.42 0.411 0.0735 1.54 2.7972 0.9762 2217 Bio2_000472 CS(=O)(=O)Nc1ccc(cc1OC2CCCCC2)[N+](=O)[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P06 positive control 0.373 0.0405 1.59 0.382 0.0445 0.93 1.7843 0.9675 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P07 mock treatment 0.353 0.0205 0.8 0.384 0.0465 0.97 1.2578 0.9955 1917 Bio2_000473 CC1=C(C)C(=O)C(=C(C)C1=O)CCCCC#CCCCC#CCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P08 positive control 0.381 0.0485 1.91 0.394 0.0565 1.18 2.1843 0.9737 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P09 mock treatment 0.388 0.0555 2.18 0.396 0.0585 1.23 2.4085 0.9628 3002232 Bio2_000474 *CC/C(=C/Cc1c(O)c2C(=O)OCc2c(C)c1OC)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P10 positive control 0.402 0.0695 2.73 0.408 0.0705 1.48 2.9753 0.9583 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P11 mock treatment 0.557 0.224 8.83 0.466 0.129 2.69 8.1428 0.8825 2288 Bio2_000475 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P12 positive control 0.392 0.0595 2.34 0.389 0.0515 1.08 2.4161 0.9383 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P13 mock treatment 0.368 0.0355 1.39 0.372 0.0345 0.72 1.4973 0.9532 3104904 Bio2_000476 C1C[C@H]2CCCCCC[C@H]3CCN4CCC[C@H](CCCCCC[C@H]5CCN(C1)[C@@H]2O5)[C@H]4O3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P14 positive control 0.37 0.0375 1.47 0.365 0.0275 0.58 1.4493 0.9161 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P15 mock treatment 0.508 0.175 6.9 0.524 0.187 3.9 7.6387 0.9636 1907782 Bio2_000477 Oc1ccc(/C=C(/C#N)\C(=O)OC\C=C\c2ccccc2)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P16 positive control 0.373 0.0405 1.59 0.401 0.0635 1.33 2.0654 0.996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P17 mock treatment 0.345 0.0125 0.49 0.345 0.00754 0.16 0.4583 0.8897 3104917 Bio2_000478 C/C=C/C\C=C\CCC(=O)[C@H]1O[C@H]1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P18 positive control 0.357 0.0245 0.96 0.359 0.0215 0.45 0.9991 0.9403 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P19 mock treatment 0.338 0.00547 0.22 0.368 0.0305 0.64 0.604 0.8958 1395 Bio2_000479 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P20 positive control 0.342 0.00947 0.37 0.367 0.0295 0.62 0.7005 0.9706 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P21 mock treatment 0.336 0.00347 0.14 0.348 0.0105 0.22 0.2525 0.9734 1303231 Bio2_000480 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P22 positive control 0.344 0.0115 0.45 0.338 5.39E-4 0.01 0.3269 0.7246 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P23 positive control 0.342 0.00947 0.37 0.337 -4.61E-4 -0.01 0.2565 0.6886 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1362 P24 positive control 0.1 -0.233 -9.14 0.092 -0.245 -5.14 -10.0968 -0.9628 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A01 compound treatment 0.333 -0.0205 -0.8 0.341 -0.0118 -0.25 -0.7436 -0.8836 2065880 IFLab1_000001 CCC(=O)Nc1nc(cs1)c2ccc(C)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A02 compound treatment 0.378 0.0245 0.96 0.384 0.0312 0.65 1.1438 0.9819 2065881 IFLab1_000002 Cc1ccc(NC(=O)/C=C/c2ccc(o2)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A03 compound treatment 0.308 -0.0455 -1.79 0.33 -0.0228 -0.48 -1.6014 -0.8656 1391894 IFLab1_000003 O=C(Nc1ccccc1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A04 compound treatment 0.309 -0.0445 -1.75 0.317 -0.0358 -0.75 -1.766 -0.9285 2065882 IFLab1_000004 OC(CCl)c1ccc(cc1)n2cncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A05 compound treatment 0.309 -0.0445 -1.75 0.329 -0.0238 -0.5 -1.5884 -0.8739 1605892 IFLab1_000005 COc1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A06 compound treatment 0.318 -0.0355 -1.39 0.326 -0.0268 -0.56 -1.3826 -0.92 1488846 IFLab1_000006 Clc1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A07 compound treatment 0.346 -0.00746 -0.29 0.32 -0.0328 -0.69 -0.6929 -0.928 1471155 IFLab1_000007 CCOc1ccc2nc(NC(=O)c3ccc(C)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A08 compound treatment 0.324 -0.0295 -1.16 0.321 -0.0318 -0.67 -1.2897 -0.9654 1253831 IFLab1_000008 COc1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A09 compound treatment 0.332 -0.0215 -0.84 0.342 -0.0108 -0.23 -0.7566 -0.8661 2065883 IFLab1_000009 CCOc1ccc(cc1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A10 compound treatment 0.316 -0.0375 -1.47 0.319 -0.0338 -0.71 -1.5418 -0.9436 1330417 IFLab1_000010 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A11 compound treatment 0.385 0.0315 1.24 0.375 0.0222 0.46 1.2052 0.9102 1508840 IFLab1_000011 Clc1ccccc1C(=O)N=c2[nH]c3ccc4ccccc4c3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A12 compound treatment 0.322 -0.0315 -1.24 0.32 -0.0328 -0.69 -1.3601 -0.9614 1134756 IFLab1_000012 COc1ccc(cc1)c2csc(NC(=O)c3ccc(C#N)cc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A13 compound treatment 0.34 -0.0135 -0.53 0.328 -0.0248 -0.52 -0.7413 -1.0 1921843 IFLab1_000013 Cc1cc(Sc2nnnn2c3ccccc3)nc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A14 compound treatment 0.328 -0.0255 -1.0 0.312 -0.0408 -0.85 -1.3117 -0.9969 1444027 IFLab1_000014 O=C(Nc1ccccc1)c2nc[nH]c2C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A15 compound treatment 0.333 -0.0205 -0.8 0.314 -0.0388 -0.81 -1.1431 -1.0 1615284 IFLab1_000015 CN1N=Nc2ccc(Br)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A16 compound treatment 0.328 -0.0255 -1.0 0.329 -0.0238 -0.5 -1.0602 -0.9481 2065884 IFLab1_000016 O/C(=N/Cc1ccccc1)/NC2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A17 compound treatment 0.323 -0.0305 -1.2 0.32 -0.0328 -0.69 -1.3323 -0.9651 1258148 IFLab1_000017 CC(=O)NCC(=O)Nc1ccc(Br)cc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A18 compound treatment 0.349 -0.00446 -0.18 0.325 -0.0278 -0.58 -0.5355 -0.881 1392876 IFLab1_000018 COc1ccc(cc1)C(=O)CSc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A19 compound treatment 0.329 -0.0245 -0.96 0.327 -0.0258 -0.54 -1.0619 -0.9628 1379853 IFLab1_000019 CCOc1ccc(cc1)C(=O)Nc2nnc(s2)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A20 compound treatment 0.328 -0.0255 -1.0 0.343 -0.00981 -0.21 -0.853 -0.8348 1616408 IFLab1_000020 CCOC(=O)c1sc(NC(=O)c2ccc(F)cc2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A21 compound treatment 0.323 -0.0305 -1.2 0.315 -0.0378 -0.79 -1.4063 -0.9798 2065885 IFLab1_000021 Cc1ccc2[nH]c(=NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A22 compound treatment 0.343 -0.0105 -0.41 0.319 -0.0338 -0.71 -0.7911 -0.9667 1428497 IFLab1_000022 Cc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A23 mock treatment 0.317 -0.0365 -1.43 0.317 -0.0358 -0.75 -1.5435 -0.9542 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 A24 mock treatment 0.079 -0.274 -10.79 0.078 -0.275 -5.75 -11.6969 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B01 compound treatment 0.278 -0.0755 -2.97 0.271 -0.0818 -1.71 -3.3085 -0.9659 2065886 IFLab1_000023 O=C(NCSc1ccncn1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B02 compound treatment 0.353 -4.59E-4 -0.02 0.349 -0.00381 -0.08 -0.0692 -0.8459 1463606 IFLab1_000024 C1COc2cc(ccc2O1)c3cc4ccccn4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B03 compound treatment 0.315 -0.0385 -1.51 0.318 -0.0348 -0.73 -1.5843 -0.9439 2065887 IFLab1_000025 BrC(=C(NC(=O)c1ccccc1)C#N)Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B04 compound treatment 0.325 -0.0285 -1.12 0.328 -0.0248 -0.52 -1.1584 -0.939 2065888 IFLab1_000026 Cc1n[nH]c(C)c1Sc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B05 compound treatment 0.333 -0.0205 -0.8 0.326 -0.0268 -0.56 -0.9655 -0.9845 1583892 IFLab1_000027 Cc1nc(c(o1)N2CCOCC2)S(=O)(=O)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B06 compound treatment 0.321 -0.0325 -1.28 0.32 -0.0328 -0.69 -1.3879 -0.9577 1435296 IFLab1_000028 COc1ccc(COCC(O)CN2CCCCC2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B07 compound treatment 0.34 -0.0135 -0.53 0.334 -0.0188 -0.39 -0.6525 -0.9894 2065889 IFLab1_000029 Brc1ccc(cc1)C(=O)CN2C(=N)Cc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B08 compound treatment 0.347 -0.00646 -0.25 0.345 -0.00781 -0.16 -0.2952 -0.9773 2065890 IFLab1_000030 COC(=O)c1ccccc1NC(=O)/C=C/c2ccc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B09 compound treatment 0.339 -0.0145 -0.57 0.331 -0.0218 -0.46 -0.7247 -0.9941 1352752 IFLab1_000031 Clc1ccccc1C(=O)OCCN2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B10 compound treatment 0.32 -0.0335 -1.32 0.338 -0.0148 -0.31 -1.1494 -0.8504 1300150 IFLab1_000032 CCOC(=O)c1csc(NC(=O)C(C)(C)C)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B11 compound treatment 0.329 -0.0245 -0.96 0.324 -0.0288 -0.6 -1.1063 -0.9747 1376524 IFLab1_000033 O=C(CC1(CC2CC3CC(C2)C1)C3)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B12 compound treatment 0.319 -0.0345 -1.35 0.331 -0.0218 -0.46 -1.2808 -0.8958 1069951 IFLab1_000034 CC(=O)NS(=O)(=O)c1ccc(C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B13 compound treatment 0.312 -0.0415 -1.63 0.301 -0.0518 -1.08 -1.9193 -0.9804 1002571 IFLab1_000035 Oc1ccc(Nc2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B14 compound treatment 0.314 -0.0395 -1.55 0.323 -0.0298 -0.62 -1.5382 -0.9199 2065891 IFLab1_000036 Brc1ccc(/N=C\2/CCCCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B15 compound treatment 0.327 -0.0265 -1.04 0.334 -0.0188 -0.39 -1.014 -0.9116 1314233 IFLab1_000037 O=C(CC1Sc2ccccc2NC1=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B16 compound treatment 0.321 -0.0325 -1.28 0.332 -0.0208 -0.44 -1.2104 -0.8976 2065892 IFLab1_000038 O/C(=N/C1CCCCC1)/NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B17 compound treatment 0.333 -0.0205 -0.8 0.336 -0.0168 -0.35 -0.8176 -0.9312 1571502 IFLab1_000039 OCCC1(CC2CC3C1)CC(CCO)(C2)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B18 compound treatment 0.105 -0.248 -9.77 0.115 -0.238 -4.98 -10.4266 -0.951 1954 IFLab1_000040 Cc1ccc(cc1)S(=O)(=O)/C=C/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B19 compound treatment 0.322 -0.0315 -1.24 0.323 -0.0298 -0.62 -1.3157 -0.9498 2065893 IFLab1_000041 CN(C)C(=O)C1(CC2(C)CC3(C)CC(C)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B20 compound treatment 0.326 -0.0275 -1.08 0.335 -0.0178 -0.37 -1.027 -0.8991 2065894 IFLab1_000042 Clc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)N3CCOCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B21 compound treatment 0.338 -0.0155 -0.61 0.334 -0.0188 -0.39 -0.7081 -0.9779 1589343 IFLab1_000043 COc1ccc2nc(NC(=O)c3cccnc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B22 compound treatment 0.333 -0.0205 -0.8 0.335 -0.0178 -0.37 -0.8324 -0.9389 2065895 IFLab1_000044 O=C(NCC1CCCO1)/C(=C\C=C/c2ccccc2)/NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B23 mock treatment 0.329 -0.0245 -0.96 0.327 -0.0258 -0.54 -1.0619 -0.9628 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 B24 mock treatment 0.078 -0.275 -10.83 0.078 -0.275 -5.75 -11.7247 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C01 compound treatment 0.328 -0.0255 -1.0 0.334 -0.0188 -0.39 -0.9862 -0.9168 2065896 IFLab1_000045 CC1CCc2nc(NC(=O)C)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C02 compound treatment 0.32 -0.0335 -1.32 0.333 -0.0198 -0.41 -1.2234 -0.8869 1466153 IFLab1_000046 CC(C)(C)NC(=O)c1ccc2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C03 compound treatment 0.313 -0.0405 -1.59 0.314 -0.0388 -0.81 -1.6991 -0.9513 1442113 IFLab1_000047 CCOC(=O)COc1c(Br)cc(Br)c2cccnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C04 compound treatment 0.376 0.0225 0.89 0.383 0.0302 0.63 1.0734 0.9862 1148405 IFLab1_000048 COc1cc(OC)cc(c1)C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C05 compound treatment 0.323 -0.0305 -1.2 0.317 -0.0358 -0.75 -1.3767 -0.9745 1479838 IFLab1_000049 COc1ccccc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C06 compound treatment 0.346 -0.00746 -0.29 0.365 0.0122 0.26 -0.027 -0.0695 2065897 IFLab1_000050 CCC(=O)Nc1nc2ccc(Cl)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C07 compound treatment 0.338 -0.0155 -0.61 0.35 -0.00281 -0.06 -0.4714 -0.7719 1265435 IFLab1_000051 CCC(=O)Nc1ccc(cc1OC)c2ccc(NC(=O)CC)c(OC)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C08 compound treatment 0.365 0.0115 0.45 0.368 0.0152 0.32 0.5456 0.9848 1654530 IFLab1_000052 COc1cccc2sc(NC(=O)c3ccc(Br)cc3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C09 compound treatment 0.326 -0.0275 -1.08 0.332 -0.0208 -0.44 -1.0714 -0.9203 1553650 IFLab1_000053 CCOc1ccc(cc1)C(=O)Nc2nc3c(OC)cccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C10 compound treatment 0.322 -0.0315 -1.24 0.329 -0.0238 -0.5 -1.227 -0.9201 1915458 IFLab1_000054 OC(=O)/C=C/c1cccc(NC(=O)c2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C11 compound treatment 0.348 -0.00546 -0.21 0.358 0.00519 0.11 -0.075 -0.3118 1515224 IFLab1_000055 COc1ccc(cc1)C(=O)N=c2[nH]c3ccc4ccccc4c3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C12 compound treatment 0.329 -0.0245 -0.96 0.331 -0.0218 -0.46 -1.0028 -0.942 1313540 IFLab1_000056 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2sc3CCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C13 compound treatment 0.343 -0.0105 -0.41 0.321 -0.0318 -0.67 -0.7615 -0.9732 1280845 IFLab1_000057 Brc1ccc(o1)C(=O)Oc2ccc(cc2)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C14 compound treatment 0.329 -0.0245 -0.96 0.316 -0.0368 -0.77 -1.2247 -0.994 1296776 IFLab1_000058 COc1ccc(cc1)c2[nH]c(=N)sc2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C15 compound treatment 0.334 -0.0195 -0.77 0.332 -0.0208 -0.44 -0.849 -0.9643 1510463 IFLab1_000059 CCOC(=O)N1CC(=O)Nc2ccc(Br)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C16 compound treatment 0.333 -0.0205 -0.8 0.337 -0.0158 -0.33 -0.8028 -0.9229 2065898 IFLab1_000060 Clc1ccc(cc1Cl)c2cn3CCCc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C17 compound treatment 0.356 0.00254 0.1 0.357 0.00419 0.09 0.1326 0.9979 2065899 IFLab1_000061 Oc1ccccc1/C=N/c2ccc(Br)cc2C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C18 compound treatment 0.332 -0.0215 -0.84 0.331 -0.0218 -0.46 -0.9194 -0.9584 1053847 IFLab1_000062 O=C1CSC(N1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C19 compound treatment 0.332 -0.0215 -0.84 0.342 -0.0108 -0.23 -0.7566 -0.8661 1466812 IFLab1_000063 CC(C)c1nnc(NC(=O)c2ccc(cc2)c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C20 compound treatment 0.36 0.00654 0.26 0.369 0.0162 0.34 0.4214 0.9908 1354815 IFLab1_000064 CCOC(=O)c1sc(NC(=O)c2cccc(OC)c2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C21 compound treatment 0.31 -0.0435 -1.71 0.33 -0.0228 -0.48 -1.5458 -0.8713 2065900 IFLab1_000065 Cc1ccc2[nH]c(=NC(=O)C(C)(C)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C22 compound treatment 0.336 -0.0175 -0.69 0.334 -0.0188 -0.39 -0.7638 -0.9652 1437324 IFLab1_000066 CCC(=O)N1CC(=O)Nc2ccc(Br)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C23 mock treatment 0.325 -0.0285 -1.12 0.323 -0.0298 -0.62 -1.2323 -0.9619 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 C24 mock treatment 0.078 -0.275 -10.83 0.079 -0.274 -5.73 -11.7099 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D01 compound treatment 0.346 -0.00746 -0.29 0.347 -0.00581 -0.12 -0.2934 -0.924 1916257 IFLab1_000067 O=C(NCSc1ccnc(SCNC(=O)c2ccccc2)n1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D02 compound treatment 0.319 -0.0345 -1.35 0.323 -0.0298 -0.62 -1.3992 -0.938 2065901 IFLab1_000068 C/C(=N\O)/C(=O)c1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D03 compound treatment 0.359 0.00554 0.22 0.345 -0.00781 -0.16 0.0385 0.1412 1254249 IFLab1_000069 N#Cc1nc(CNc2ccccc2)oc1Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D04 compound treatment 0.356 0.00254 0.1 0.338 -0.0148 -0.31 -0.1485 -0.4561 1221113 IFLab1_000070 CC(C)c1ccc(C)cc1OCC(O)CN2CCN(C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D05 compound treatment 0.353 -4.59E-4 -0.02 0.345 -0.00781 -0.16 -0.1284 -0.7805 1130793 IFLab1_000071 CCOP(=O)(c1nc(oc1NC)c2ccc(Cl)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D06 compound treatment 0.332 -0.0215 -0.84 0.338 -0.0148 -0.31 -0.8158 -0.9076 2065902 IFLab1_000072 CC1CN(CC(O)COCCC2(CC3CC4CC(C3)C2)C4)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D07 compound treatment 0.334 -0.0195 -0.77 0.351 -0.00181 -0.04 -0.5678 -0.7412 2065903 IFLab1_000073 COc1ccc(cc1)c2csc3nccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D08 compound treatment 0.336 -0.0175 -0.69 0.366 0.0132 0.28 -0.2902 -0.3923 2065904 IFLab1_000074 CCCC[n+]1c(C)csc1Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D09 compound treatment 0.332 -0.0215 -0.84 0.361 0.00819 0.17 -0.4754 -0.5522 1099044 IFLab1_000075 CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2cncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D10 compound treatment 0.367 0.0135 0.53 0.394 0.0412 0.86 0.9859 0.9732 1371837 IFLab1_000076 COc1ccc(cc1OC)C(=O)Nc2nc3c(C)cccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D11 compound treatment 0.344 -0.00946 -0.37 0.369 0.0162 0.34 -0.0234 -0.0466 1304281 IFLab1_000077 CNC(=O)CC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D12 compound treatment 0.342 -0.0115 -0.45 0.37 0.0172 0.36 -0.0642 -0.1114 2065905 IFLab1_000078 COc1ccc(N)cc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D13 compound treatment 0.331 -0.0225 -0.88 0.367 0.0142 0.3 -0.4145 -0.4449 1552029 IFLab1_000079 NC(=O)c1cc(N)cc(c1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D14 compound treatment 0.338 -0.0155 -0.61 0.362 0.00919 0.19 -0.2938 -0.4609 1020564 IFLab1_000080 COc1ccc(cc1)C(=O)Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D15 compound treatment 0.342 -0.0115 -0.45 0.346 -0.00681 -0.14 -0.4194 -0.8874 1530606 IFLab1_000081 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1Cc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D16 compound treatment 0.334 -0.0195 -0.77 0.329 -0.0238 -0.5 -0.8933 -0.9784 1978847 IFLab1_000082 NC1=[N+](Cc2ccccc2C#N)Cc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D17 compound treatment 0.336 -0.0175 -0.69 0.341 -0.0118 -0.25 -0.6602 -0.9048 1464506 IFLab1_000083 NC1(CC2CC3C1)CC(C2)(C3)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D18 compound treatment 0.42 0.0665 2.62 0.417 0.0642 1.34 2.7998 0.952 2065906 IFLab1_000084 O=S1(=O)CCC(C1)NC(=S)SCCOc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D19 compound treatment 0.312 -0.0415 -1.63 0.318 -0.0348 -0.73 -1.6678 -0.9341 1158926 IFLab1_000085 CNC(=O)C1(CC2(C)CC3(C)CC(C)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D20 compound treatment 0.348 -0.00546 -0.21 0.345 -0.00781 -0.16 -0.2674 -0.991 2065907 IFLab1_000086 CNC(=O)/C(=C\c1ccco1)/NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D21 compound treatment 0.343 -0.0105 -0.41 0.336 -0.0168 -0.35 -0.5395 -0.997 1458474 IFLab1_000087 O=C(Oc1ccc(cc1)c2ccc(C#N)cc2)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D22 compound treatment 0.229 -0.124 -4.89 0.234 -0.119 -2.49 -5.2183 -0.9507 2065908 IFLab1_000088 OC(=O)CCN1C(=O)/C(=C/c2ccc(o2)c3ccccc3Cl)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D23 mock treatment 0.326 -0.0275 -1.08 0.321 -0.0318 -0.67 -1.2341 -0.973 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 D24 mock treatment 0.08 -0.273 -10.75 0.08 -0.273 -5.71 -11.6395 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E01 compound treatment 0.341 -0.0125 -0.49 0.319 -0.0338 -0.71 -0.8467 -0.9839 2065909 IFLab1_000089 CC(C)C(=O)Nc1nc2CCC(C)Cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E02 compound treatment 0.329 -0.0245 -0.96 0.341 -0.0118 -0.25 -0.8548 -0.8609 1311039 IFLab1_000090 CCOC(=O)NC(=O)c1ccc2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E03 compound treatment 0.332 -0.0215 -0.84 0.332 -0.0208 -0.44 -0.9046 -0.9527 2065910 IFLab1_000091 CN(C)c1ccc(/C=N/c2nnc(NC(=O)c3ccccc3Br)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E04 compound treatment 0.332 -0.0215 -0.84 0.337 -0.0158 -0.33 -0.8306 -0.9164 1384833 IFLab1_000092 COc1cccc2sc(NC(=O)C)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E05 compound treatment 0.359 0.00554 0.22 0.358 0.00519 0.11 0.2308 0.9483 1626820 IFLab1_000093 O=C(NCc1ccccc1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E06 compound treatment 0.346 -0.00746 -0.29 0.336 -0.0168 -0.35 -0.4561 -0.9959 1478376 IFLab1_000094 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E07 compound treatment 0.354 5.41E-4 0.02 0.367 0.0142 0.3 0.225 0.7558 2065911 IFLab1_000095 COc1ccc(cc1)c2csc(NC(=O)c3cccs3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E08 compound treatment 0.392 0.0385 1.52 0.39 0.0372 0.78 1.6218 0.952 1228205 IFLab1_000096 CCN1C(=O)c2cccc3c(NC(=O)c4ccco4)ccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E09 compound treatment 0.353 -4.59E-4 -0.02 0.372 0.0192 0.4 0.2712 0.6746 1255545 IFLab1_000097 Clc1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E10 compound treatment 0.205 -0.148 -5.84 0.246 -0.107 -2.24 -5.708 -0.9132 1922518 IFLab1_000098 NC(=O)/C=C/C(=O)Nc1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E11 compound treatment 0.325 -0.0285 -1.12 0.356 0.00319 0.07 -0.744 -0.6638 1738146 IFLab1_000099 COc1cc(OC)cc(c1)C(=O)N=c2[nH]c3ccc4ccccc4c3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E12 compound treatment 0.361 0.00754 0.3 0.391 0.0382 0.8 0.7747 0.9089 1169513 IFLab1_000100 O=C(Nc1sc2CCCc2c1C#N)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E13 compound treatment 0.337 -0.0165 -0.65 0.387 0.0342 0.72 0.0483 0.0501 1628256 IFLab1_000101 CN(C1CCS(=O)(=O)C1)C(=O)c2ccc(Br)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E14 compound treatment 0.336 -0.0175 -0.69 0.364 0.0112 0.23 -0.3198 -0.441 2065912 IFLab1_000102 Cn1c(SCC(=O)N)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E15 compound treatment 0.356 0.00254 0.1 0.38 0.0272 0.57 0.473 0.8187 2065913 IFLab1_000103 COC(=O)CNC(c1ccccc1)c2cc(C)ccc2NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E16 compound treatment 0.339 -0.0145 -0.57 0.357 0.00419 0.09 -0.34 -0.5911 2065914 IFLab1_000104 Brc1c(nc2CCCn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E17 compound treatment 0.367 0.0135 0.53 0.377 0.0242 0.51 0.7344 0.9997 2065915 IFLab1_000105 Cc1ccc(/N=C/c2ccccc2O)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E18 compound treatment 0.346 -0.00746 -0.29 0.339 -0.0138 -0.29 -0.4117 -1.0 2065916 IFLab1_000106 CCOc1ccc(NC2=NCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E19 compound treatment 0.335 -0.0185 -0.73 0.333 -0.0198 -0.41 -0.8064 -0.9647 2065917 IFLab1_000107 CC(C)c1nnc(NC(=O)Cc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E20 compound treatment 0.345 -0.00846 -0.33 0.341 -0.0118 -0.25 -0.41 -0.9893 1696886 IFLab1_000108 CCOC(=O)c1sc(NC(=O)c2ccccc2OC)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E21 compound treatment 0.356 0.00254 0.1 0.351 -0.00181 -0.04 0.0438 0.4103 1367135 IFLab1_000109 CC(C)C(=O)N=c1[nH]c(c(s1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E22 compound treatment 0.343 -0.0105 -0.41 0.344 -0.00881 -0.18 -0.4212 -0.9345 1372651 IFLab1_000110 CC(C)C(=O)N1CC(=O)Nc2ccc(Cl)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E23 mock treatment 0.331 -0.0225 -0.88 0.322 -0.0308 -0.64 -1.0803 -0.9881 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 E24 mock treatment 0.081 -0.272 -10.71 0.081 -0.272 -5.69 -11.5969 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F01 compound treatment 0.324 -0.0295 -1.16 0.321 -0.0318 -0.67 -1.2897 -0.9654 2065918 IFLab1_000111 O=C(NCSc1ncccn1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F02 compound treatment 0.322 -0.0315 -1.24 0.323 -0.0298 -0.62 -1.3157 -0.9498 1189565 IFLab1_000112 COc1ccc(OCC(=O)N(C(C)C)c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F03 compound treatment 0.326 -0.0275 -1.08 0.326 -0.0268 -0.56 -1.1602 -0.9535 1252399 IFLab1_000113 CCc1nc(C#N)c(o1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F04 compound treatment 0.342 -0.0115 -0.45 0.324 -0.0288 -0.6 -0.7449 -0.9897 1660114 IFLab1_000114 CC(C)NCC(O)COc1cc(C)ccc1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F05 compound treatment 0.323 -0.0305 -1.2 0.333 -0.0198 -0.41 -1.14 -0.8995 1295924 IFLab1_000115 CCOP(=O)(c1nc(oc1NCc2ccccc2)c3ccc(Cl)cc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F06 compound treatment 0.307 -0.0465 -1.83 0.319 -0.0338 -0.71 -1.792 -0.9148 1563210 IFLab1_000116 CCN(CC)CC(O)COC1C2CC3CC(C2)CC1C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F07 compound treatment 0.332 -0.0215 -0.84 0.346 -0.00681 -0.14 -0.6974 -0.815 2065919 IFLab1_000117 C(/N=C/1\CCCCCN1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F08 compound treatment 0.406 0.0525 2.07 0.401 0.0482 1.01 2.1738 0.9456 2065920 IFLab1_000118 ClC1=C(NC(=CS1)c2ccccc2)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F09 compound treatment 0.344 -0.00946 -0.37 0.341 -0.0118 -0.25 -0.4378 -0.9803 2065921 IFLab1_000119 Cc1n(C)c2ccccc2[n+]1CC(=O)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F10 compound treatment 0.35 -0.00346 -0.14 0.381 0.0282 0.59 0.3209 0.5301 1465253 IFLab1_000120 COc1ccc(cc1OC)C(=O)Nc2sc3CCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F11 compound treatment 0.346 -0.00746 -0.29 0.363 0.0102 0.21 -0.0566 -0.1561 1517846 IFLab1_000121 O=C(N1CCOCC1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F12 compound treatment 0.343 -0.0105 -0.41 0.355 0.00219 0.05 -0.2584 -0.6245 1227669 IFLab1_000122 COc1ccc(NC(=O)C)cc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F13 compound treatment 0.346 -0.00746 -0.29 0.392 0.0392 0.82 0.3725 0.4277 1378783 IFLab1_000123 CCCOc1ccccc1N2C(=O)CC(Nc3ccc(C)cc3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F14 compound treatment 0.349 -0.00446 -0.18 0.348 -0.00481 -0.1 -0.1952 -0.9653 1124699 IFLab1_000124 CCOc1ccc(cc1)C(=O)CSCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F15 compound treatment 0.351 -0.00246 -0.1 0.367 0.0142 0.3 0.1416 0.4534 1261357 IFLab1_000125 COC(=O)CNc1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F16 compound treatment 0.339 -0.0145 -0.57 0.369 0.0162 0.34 -0.1624 -0.2455 2065922 IFLab1_000126 Fc1ccc(cc1)c2cn3Cc4ccccc4-c3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F17 compound treatment 0.348 -0.00546 -0.21 0.338 -0.0148 -0.31 -0.3709 -0.9839 1175265 IFLab1_000127 COC(=O)C1(CC2CC3CC(N)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F18 compound treatment 0.328 -0.0255 -1.0 0.324 -0.0288 -0.6 -1.1341 -0.9705 2065923 IFLab1_000128 CC(=O)N(c1ccccc1)c2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F19 compound treatment 0.328 -0.0255 -1.0 0.337 -0.0158 -0.33 -0.9418 -0.8933 1137572 IFLab1_000129 Nc1nc(cs1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F20 compound treatment 0.314 -0.0395 -1.55 0.317 -0.0358 -0.75 -1.6269 -0.9443 2065924 IFLab1_000130 Cc1ccc(cc1)C(=O)N/C(=C/c2ccco2)/C(=O)Nc3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F21 compound treatment 0.333 -0.0205 -0.8 0.331 -0.0218 -0.46 -0.8916 -0.964 1246928 IFLab1_000131 CCOC(=O)c1cccc(n1)C(=O)Nc2ccc(Cl)cn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F22 compound treatment 0.35 -0.00346 -0.14 0.35 -0.00281 -0.06 -0.1378 -0.9297 2065925 IFLab1_000132 Cc1ccc(/C=C/2\SC(=S)N(C3CCS(=O)(=O)C3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F23 mock treatment 0.321 -0.0325 -1.28 0.325 -0.0278 -0.58 -1.314 -0.9368 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 F24 mock treatment 0.084 -0.269 -10.59 0.081 -0.272 -5.69 -11.5135 -0.9575 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G01 compound treatment 0.339 -0.0145 -0.57 0.342 -0.0108 -0.23 -0.562 -0.9184 1606974 IFLab1_000133 COc1ccccc1C(=O)Nc2nc3CCC(C)Cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G02 compound treatment 0.318 -0.0355 -1.39 0.332 -0.0208 -0.44 -1.2938 -0.8858 2065926 IFLab1_000134 CCOC(=O)c1ccc(cc1)N2Cc3ccccc3C2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G03 compound treatment 0.368 0.0145 0.57 0.352 -8.11E-4 -0.02 0.3923 0.6858 2065927 IFLab1_000135 Clc1ccc(C(=O)Nc2nnc(/N=C/c3cccs3)s2)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G04 compound treatment 0.349 -0.00446 -0.18 0.354 0.00119 0.02 -0.1064 -0.6007 1374791 IFLab1_000136 O=C(Nc1ccccc1c2nc3ccccc3[nH]2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G05 compound treatment 0.312 -0.0415 -1.63 0.316 -0.0368 -0.77 -1.6973 -0.9414 1351064 IFLab1_000137 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G06 compound treatment 0.328 -0.0255 -1.0 0.346 -0.00681 -0.14 -0.8086 -0.7997 1314536 IFLab1_000138 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G07 compound treatment 0.328 -0.0255 -1.0 0.34 -0.0128 -0.27 -0.8974 -0.866 1456201 IFLab1_000139 Cc1ccccc1N2C(=O)C3C=CC=CC3n4cnnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G08 compound treatment 0.356 0.00254 0.1 0.345 -0.00781 -0.16 -0.0449 -0.2346 1237070 IFLab1_000140 O=C(CC1Sc2ccccc2NC1=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G09 compound treatment 0.382 0.0285 1.12 0.368 0.0152 0.32 1.0182 0.873 1516945 IFLab1_000141 Cc1ccc(cc1C)c2csc(=NC(=O)c3cccc(Cl)c3)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G10 compound treatment 0.258 -0.0955 -3.75 0.297 -0.0558 -1.17 -3.4798 -0.8853 2065928 IFLab1_000142 CCOc1ccccc1NC(=O)/C=C/C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G11 compound treatment 0.386 0.0325 1.28 0.397 0.0442 0.92 1.5586 0.9873 1351750 IFLab1_000143 O=C(N=c1[nH]c2ccc3ccccc3c2s1)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G12 compound treatment 0.322 -0.0315 -1.24 0.364 0.0112 0.23 -0.7091 -0.5632 1292829 IFLab1_000144 CCOc1ccc2nc(NC(=O)c3ccc(C#N)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G13 compound treatment 0.333 -0.0205 -0.8 0.377 0.0242 0.51 -0.2109 -0.2219 1598186 IFLab1_000145 CC(C)(C)P(=O)(NCc1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G14 compound treatment 0.336 -0.0175 -0.69 0.346 -0.00681 -0.14 -0.5862 -0.8361 2065929 IFLab1_000146 CCOc1ccc(cc1)C(=O)C[n+]2ccsc2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G15 compound treatment 0.33 -0.0235 -0.92 0.355 0.00219 0.05 -0.6198 -0.6712 2065930 IFLab1_000147 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G16 compound treatment 0.306 -0.0475 -1.87 0.35 -0.00281 -0.06 -1.3611 -0.729 1112886 IFLab1_000148 Clc1ccc(cc1)c2cc3ccccn3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G17 compound treatment 0.334 -0.0195 -0.77 0.342 -0.0108 -0.23 -0.701 -0.8786 1641695 IFLab1_000149 Cc1ccc(N)c(c1)C(O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G18 compound treatment 0.34 -0.0135 -0.53 0.334 -0.0188 -0.39 -0.6525 -0.9894 1396561 IFLab1_000150 CC(=C)CN1CCN(CC1)C(c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G19 compound treatment 0.327 -0.0265 -1.04 0.332 -0.0208 -0.44 -1.0436 -0.9253 2065931 IFLab1_000151 CC(C)c1nnc(NC(=O)c2cccs2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G20 compound treatment 0.385 0.0315 1.24 0.363 0.0102 0.21 1.0277 0.8167 1139085 IFLab1_000152 CCOC(=O)c1sc(NC(=O)c2cccs2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G21 compound treatment 0.346 -0.00746 -0.29 0.321 -0.0318 -0.67 -0.6781 -0.9322 2065932 IFLab1_000153 CC(=O)Nc1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G22 compound treatment 0.334 -0.0195 -0.77 0.332 -0.0208 -0.44 -0.849 -0.9643 1455038 IFLab1_000154 CC(C)C(=O)N1CC(=O)Nc2ccc(C)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G23 mock treatment 0.322 -0.0315 -1.24 0.319 -0.0338 -0.71 -1.3749 -0.9649 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 G24 mock treatment 0.081 -0.272 -10.71 0.082 -0.271 -5.67 -11.5821 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H01 compound treatment 0.348 -0.00546 -0.21 0.359 0.00619 0.13 -0.0602 -0.2401 2065933 IFLab1_000155 Cc1ccc(cc1)C(=O)NC(=C(Cl)Cl)S(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H02 compound treatment 0.325 -0.0285 -1.12 0.327 -0.0258 -0.54 -1.1732 -0.9442 1089066 IFLab1_000156 OC(=O)CN1C(=O)C2C3CC(C=C3)C2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H03 compound treatment 0.321 -0.0325 -1.28 0.342 -0.0108 -0.23 -1.0624 -0.8197 2065934 IFLab1_000157 CNc1oc(nc1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H04 compound treatment 0.326 -0.0275 -1.08 0.331 -0.0218 -0.46 -1.0862 -0.9266 1134668 IFLab1_000158 CC(C)NCC(O)COC1CC(C)CCC1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H05 compound treatment 0.342 -0.0115 -0.45 0.339 -0.0138 -0.29 -0.523 -0.977 1022918 IFLab1_000159 N=c1[nH]c(c(s1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H06 compound treatment 0.323 -0.0305 -1.2 0.333 -0.0198 -0.41 -1.14 -0.8995 1601554 IFLab1_000160 COc1cc(ccc1N)C2(CCCCC2)c3ccc(N)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H07 compound treatment 0.356 0.00254 0.1 0.332 -0.0208 -0.44 -0.2373 -0.5311 2065935 IFLab1_000161 COc1ccc(cc1)C(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H08 compound treatment 0.354 5.41E-4 0.02 0.337 -0.0158 -0.33 -0.2189 -0.6603 1198451 IFLab1_000162 CCOC(=O)c1csc(NC(=O)c2ccccc2OC)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H09 compound treatment 0.342 -0.0115 -0.45 0.355 0.00219 0.05 -0.2862 -0.632 1391379 IFLab1_000163 COc1ccc(C(=O)CSc2nc3ccccc3[nH]2)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H10 compound treatment 0.32 -0.0335 -1.32 0.337 -0.0158 -0.33 -1.1642 -0.8582 1156950 IFLab1_000164 COc1cccc(c1)C(=O)Nc2ccc3nc(SC)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H11 compound treatment 0.33 -0.0235 -0.92 0.343 -0.00981 -0.21 -0.7974 -0.8438 2065936 IFLab1_000165 Cc1ccc(C)c(SCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H12 compound treatment 0.338 -0.0155 -0.61 0.347 -0.00581 -0.12 -0.5158 -0.8321 1337746 IFLab1_000166 CC(=O)Nc1ccc(NC(=O)CSc2ccccc2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H13 compound treatment 0.316 -0.0375 -1.47 0.355 0.00219 0.05 -1.0091 -0.6848 2065937 IFLab1_000167 CC(=O)Nc1sccc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H14 compound treatment 0.34 -0.0135 -0.53 0.364 0.0112 0.23 -0.2086 -0.3605 2065938 IFLab1_000168 CC(C)N(C(=O)C[n+]1ccsc1N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H15 compound treatment 0.336 -0.0175 -0.69 0.36 0.00719 0.15 -0.379 -0.5393 1864902 IFLab1_000169 O=S(=O)(NCc1ccccc1)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H16 compound treatment 0.345 -0.00846 -0.33 0.358 0.00519 0.11 -0.1584 -0.4527 2065939 IFLab1_000170 CCOc1ccc(cc1)C(=O)/C(=N/O)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H17 compound treatment 0.344 -0.00946 -0.37 0.355 0.00219 0.05 -0.2306 -0.6154 1313832 IFLab1_000171 NC(=O)C1(CC2CC3CC(C2)CC1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H18 compound treatment 0.317 -0.0365 -1.43 0.334 -0.0188 -0.39 -1.292 -0.8691 2065940 IFLab1_000172 CCOC(=O)C1=C(C)NC(=NC1c2ccccc2)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H19 compound treatment 0.334 -0.0195 -0.77 0.337 -0.0158 -0.33 -0.775 -0.9297 1727964 IFLab1_000173 CNC(=O)C1(CC2CC3C1)CC(C2)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H20 compound treatment 0.361 0.00754 0.3 0.363 0.0102 0.21 0.3604 0.9869 2065941 IFLab1_000174 O=C/1Nc2ccccc2\C1=N\C3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H21 compound treatment 0.341 -0.0125 -0.49 0.345 -0.00781 -0.16 -0.462 -0.8946 1490379 IFLab1_000175 Nc1ccc(CCc2nc3cc(N)ccc3o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H22 compound treatment 0.352 -0.00146 -0.06 0.349 -0.00381 -0.08 -0.097 -0.987 2065942 IFLab1_000176 Cc1ccc(cc1)C2=N/C(=C\c3cccs3)/C(=O)O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H23 mock treatment 0.328 -0.0255 -1.0 0.321 -0.0318 -0.67 -1.1785 -0.9804 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 H24 mock treatment 0.083 -0.27 -10.63 0.084 -0.269 -5.63 -11.4969 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I01 compound treatment 0.325 -0.0285 -1.12 0.347 -0.00581 -0.12 -0.8772 -0.7794 1167788 IFLab1_000177 COc1ccccc1c2csc(N)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I02 compound treatment 0.329 -0.0245 -0.96 0.336 -0.0168 -0.35 -0.9288 -0.907 2065943 IFLab1_000178 CN(C)CCOC(=O)c1ccc(cc1)N2Cc3ccccc3C2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I03 compound treatment 0.358 0.00454 0.18 0.362 0.00919 0.19 0.2622 0.9993 1336253 IFLab1_000179 CC(=O)Oc1ccc(cc1)c2ccc(cc2)C(=O)Nc3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I04 compound treatment 0.372 0.0185 0.73 0.365 0.0122 0.26 0.6958 0.901 2065944 IFLab1_000180 Cc1nc2ccc(NC(=O)/C=C/c3ccccc3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I05 compound treatment 0.35 -0.00346 -0.14 0.338 -0.0148 -0.31 -0.3153 -0.9317 1309772 IFLab1_000181 COc1ccccc1NC(=O)c2ccc(cc2)S(=O)(=O)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I06 compound treatment 0.36 0.00654 0.26 0.356 0.00319 0.07 0.229 0.8621 1163700 IFLab1_000182 O=C(Nc1nccs1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I07 compound treatment 0.39 0.0365 1.44 0.373 0.0202 0.42 1.3146 0.8779 2065945 IFLab1_000183 CC(C)(C)C(=O)Nc1nnc(/N=C/c2ccc(Br)s2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I08 compound treatment 0.356 0.00254 0.1 0.339 -0.0138 -0.29 -0.1337 -0.4373 2065946 IFLab1_000184 COc1ccc(/C=C/C(=O)N2CCOCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I09 compound treatment 0.365 0.0115 0.45 0.365 0.0122 0.26 0.5012 0.9629 1398037 IFLab1_000185 Cc1ccc(cc1C)c2csc(=NC(=O)c3ccccc3F)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I10 compound treatment 0.351 -0.00246 -0.1 0.331 -0.0218 -0.46 -0.3911 -0.8383 1613217 IFLab1_000186 O=C(CC1Nc2ccccc2NC1=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I11 compound treatment 0.333 -0.0205 -0.8 0.337 -0.0158 -0.33 -0.8028 -0.9229 1164573 IFLab1_000187 COc1cc(OC)cc(c1)C(=O)N=c2[nH]c(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I12 compound treatment 0.35 -0.00346 -0.14 0.367 0.0142 0.3 0.1138 0.3484 1722777 IFLab1_000188 CC(=O)Nc1ccc2nc(NC(=O)c3ccc(C#N)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I13 compound treatment 0.338 -0.0155 -0.61 0.367 0.0142 0.3 -0.2198 -0.325 1916136 IFLab1_000189 CC(C)C1(C)NC(=NC1=O)c2ncccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I14 compound treatment 0.34 -0.0135 -0.53 0.362 0.00919 0.19 -0.2382 -0.4231 1136476 IFLab1_000190 CCOc1ccc(Cc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I15 compound treatment 0.338 -0.0155 -0.61 0.354 0.00119 0.02 -0.4122 -0.6776 2065947 IFLab1_000191 CCOC(=O)Nc1ccc(Br)cc1C(NCC(=O)OC)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I16 compound treatment 0.338 -0.0155 -0.61 0.354 0.00119 0.02 -0.4122 -0.6776 1046914 IFLab1_000192 OC(=O)CCC(=O)Nc1nccs1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I17 compound treatment 0.321 -0.0325 -1.28 0.356 0.00319 0.07 -0.8552 -0.6692 2065948 IFLab1_000193 CCc1nnc(NC(=O)c2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I18 compound treatment 0.321 -0.0325 -1.28 0.312 -0.0408 -0.85 -1.5063 -0.9809 1702732 IFLab1_000194 Nc1nc(c(s1)C(=O)Nc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I19 compound treatment 0.32 -0.0335 -1.32 0.338 -0.0148 -0.31 -1.1494 -0.8504 1571935 IFLab1_000195 Cc1ccc2[nH]c(=NC(=O)c3ccccc3C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I20 compound treatment 0.344 -0.00946 -0.37 0.344 -0.00881 -0.18 -0.3934 -0.9476 1688422 IFLab1_000196 CCOC(=O)c1sc(NC(=O)c2ccco2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I21 compound treatment 0.325 -0.0285 -1.12 0.326 -0.0268 -0.56 -1.188 -0.949 2065949 IFLab1_000197 CC(=O)Nc1ccc2nc(NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I22 compound treatment 0.319 -0.0345 -1.35 0.319 -0.0338 -0.71 -1.4583 -0.9541 1724906 IFLab1_000198 CCCCC(=O)N1CC(=O)Nc2ccc(C)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I23 mock treatment 0.33 -0.0235 -0.92 0.33 -0.0228 -0.48 -0.9898 -0.953 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 I24 mock treatment 0.082 -0.271 -10.67 0.085 -0.268 -5.6 -11.5099 -0.9548 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J01 compound treatment 0.328 -0.0255 -1.0 0.341 -0.0118 -0.25 -0.8826 -0.856 1913601 IFLab1_000199 COc1ccc2sc(C(=O)O)c(Br)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J02 compound treatment 0.336 -0.0175 -0.69 0.352 -8.11E-4 -0.02 -0.4974 -0.7244 2065950 IFLab1_000200 Nc1ccc(Br)cc1c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J03 compound treatment 0.329 -0.0245 -0.96 0.345 -0.00781 -0.16 -0.7956 -0.8156 1731303 IFLab1_000201 COC(=O)c1nc(oc1N2CCOCC2)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J04 compound treatment 0.324 -0.0295 -1.16 0.341 -0.0118 -0.25 -0.9938 -0.8391 1229921 IFLab1_000202 CC(C)C1CCC(C)CC1OCC(O)CNC(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J05 compound treatment 0.336 -0.0175 -0.69 0.336 -0.0168 -0.35 -0.7342 -0.9518 1170020 IFLab1_000203 COc1ccc(cc1)c2nc(N)sc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J06 compound treatment 0.324 -0.0295 -1.16 0.326 -0.0268 -0.56 -1.2158 -0.9446 1020977 IFLab1_000204 CS(=O)(=O)c1ccc(N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J07 compound treatment 0.354 5.41E-4 0.02 0.359 0.00619 0.13 0.1066 0.8123 2065951 IFLab1_000205 CCOc1ccc(cc1)C(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J08 compound treatment 0.374 0.0205 0.81 0.33 -0.0228 -0.48 0.2335 0.2489 1509443 IFLab1_000206 COc1ccc(cc1OC)C(=O)Nc2nc3c(OC)cccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J09 compound treatment 0.313 -0.0405 -1.59 0.322 -0.0308 -0.64 -1.5808 -0.9209 2065952 IFLab1_000207 Cc1cc(ccc1O)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J10 compound treatment 0.358 0.00454 0.18 0.35 -0.00281 -0.06 0.0846 0.4503 1366440 IFLab1_000208 CSc1nc2ccc(NC(=O)c3cccc(Cl)c3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J11 compound treatment 0.364 0.0105 0.41 0.341 -0.0118 -0.25 0.1183 0.2451 1250082 IFLab1_000209 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J12 compound treatment 0.334 -0.0195 -0.77 0.334 -0.0188 -0.39 -0.8194 -0.9523 2065953 IFLab1_000210 FC(F)(F)C(=O)NCC1(CC2CC3C1)CC(CNC(=O)C(F)(F)F)(C2)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J13 compound treatment 0.349 -0.00446 -0.18 0.338 -0.0148 -0.31 -0.3431 -0.9636 1116743 IFLab1_000211 COC(=O)c1cc(Cl)c(cc1Cl)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J14 compound treatment 0.332 -0.0215 -0.84 0.343 -0.00981 -0.21 -0.7418 -0.8542 2065954 IFLab1_000212 CCOc1ccc(cc1)C2=C(C)SC(=NN2)Nc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J15 compound treatment 0.308 -0.0455 -1.79 0.345 -0.00781 -0.16 -1.3794 -0.7686 2065955 IFLab1_000213 O=S(=O)(/C=C/c1ccccc1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J16 compound treatment 0.333 -0.0205 -0.8 0.343 -0.00981 -0.21 -0.714 -0.86 2065956 IFLab1_000214 OC1=NC(C(=O)N1)(c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J17 compound treatment 0.345 -0.00846 -0.33 0.342 -0.0108 -0.23 -0.3952 -0.9824 2065957 IFLab1_000215 ClC1(CC2CC3C1)CC(C2)(C3)C(=O)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J18 compound treatment 0.351 -0.00246 -0.1 0.323 -0.0298 -0.62 -0.5095 -0.8071 2065958 IFLab1_000216 CN(C)C(=O)/C(=C\c1ccco1)/NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J19 compound treatment 0.356 0.00254 0.1 0.358 0.00519 0.11 0.1474 0.9991 1364663 IFLab1_000217 COc1cc(OC)cc(c1)C(=O)NC(C(=O)O)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J20 compound treatment 0.347 -0.00646 -0.25 0.351 -0.00181 -0.04 -0.2064 -0.8037 2065959 IFLab1_000218 O=C(NC1CCCCC1)/C(=C\c2cccs2)/NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J21 compound treatment 0.35 -0.00346 -0.14 0.344 -0.00881 -0.18 -0.2266 -0.9888 1331163 IFLab1_000219 CCc1ccc(OC(=O)c2cncc(Br)c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J22 compound treatment 0.317 -0.0365 -1.43 0.311 -0.0418 -0.87 -1.6323 -0.972 2065960 IFLab1_000220 CN(Cc1ccccc1)C(=O)c2sc3ccccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J23 mock treatment 0.327 -0.0265 -1.04 0.331 -0.0218 -0.46 -1.0584 -0.9316 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 J24 mock treatment 0.083 -0.27 -10.63 0.086 -0.267 -5.58 -11.4673 -0.9548 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K01 compound treatment 0.349 -0.00446 -0.18 0.345 -0.00781 -0.16 -0.2396 -0.9994 1482153 IFLab1_000221 CN1C(=O)CN=C(c2ccccc2)c3cc(C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K02 compound treatment 0.323 -0.0305 -1.2 0.352 -8.11E-4 -0.02 -0.8588 -0.7171 2065961 IFLab1_000222 COC(=O)c1cccc(c1)N2Cc3ccccc3C2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K03 compound treatment 0.364 0.0105 0.41 0.352 -8.11E-4 -0.02 0.2811 0.6776 1434293 IFLab1_000223 Cc1cccc2sc(NC(=O)c3ccccc3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K04 compound treatment 0.347 -0.00646 -0.25 0.337 -0.0158 -0.33 -0.4135 -0.9915 1553252 IFLab1_000224 Clc1ccc2nc(NC(=O)Cc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K05 compound treatment 0.329 -0.0245 -0.96 0.334 -0.0188 -0.39 -0.9584 -0.9223 1384219 IFLab1_000225 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K06 compound treatment 0.365 0.0115 0.45 0.392 0.0392 0.82 0.9007 0.961 2065962 IFLab1_000226 Oc1ccc(/N=C/c2ccccc2)cc1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K07 compound treatment 0.339 -0.0145 -0.57 0.347 -0.00581 -0.12 -0.488 -0.8394 2065963 IFLab1_000227 Cc1cccc(c1)C(=O)Nc2nnc(/N=C/c3ccc(Br)s3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K08 compound treatment 0.338 -0.0155 -0.61 0.336 -0.0168 -0.35 -0.6786 -0.9662 1915824 IFLab1_000228 OC(=O)CCCCc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K09 compound treatment 0.353 -4.59E-4 -0.02 0.353 1.89E-4 0.0 -0.01 -0.5393 1414943 IFLab1_000229 Cc1ccc(cc1C)c2csc(=NC(=O)c3cccs3)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K10 compound treatment 0.342 -0.0115 -0.45 0.345 -0.00781 -0.16 -0.4342 -0.9059 1181259 IFLab1_000230 COc1cc(C)nc(n1)N(CCO)CCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K11 compound treatment 0.332 -0.0215 -0.84 0.339 -0.0138 -0.29 -0.801 -0.8981 1174301 IFLab1_000231 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)N=c2[nH]c(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K12 compound treatment 0.356 0.00254 0.1 0.366 0.0132 0.28 0.2658 0.9055 1544781 IFLab1_000232 Brc1ccc2[nH]c(=O)cc(c3ccccc3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K13 compound treatment 0.351 -0.00246 -0.1 0.34 -0.0128 -0.27 -0.2579 -0.9051 2065964 IFLab1_000233 O=C/1/C(=C/c2ccncc2)/CC\C1=C/c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K14 compound treatment 0.339 -0.0145 -0.57 0.348 -0.00481 -0.1 -0.4732 -0.8196 2065965 IFLab1_000234 C1Cc2nc(cn2C1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K15 compound treatment 0.343 -0.0105 -0.41 0.342 -0.0108 -0.23 -0.4508 -0.9604 2065966 IFLab1_000235 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K16 compound treatment 0.341 -0.0125 -0.49 0.342 -0.0108 -0.23 -0.5064 -0.9384 2065967 IFLab1_000236 Brc1ccc(/N=C\2/CCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K17 compound treatment 0.349 -0.00446 -0.18 0.342 -0.0108 -0.23 -0.284 -0.9921 2065968 IFLab1_000237 CCc1nnc(NC(=O)Cc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K18 compound treatment 0.353 -4.59E-4 -0.02 0.354 0.00119 0.02 0.0048 0.1568 1163040 IFLab1_000238 CCc1nc2sc3CCCc3c2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K19 compound treatment 0.347 -0.00646 -0.25 0.358 0.00519 0.11 -0.1028 -0.3722 1246151 IFLab1_000239 Cc1ccc2[nH]c(=NC(=O)c3ccc(cc3)c4ccccc4)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K20 compound treatment 0.353 -4.59E-4 -0.02 0.341 -0.0118 -0.25 -0.1875 -0.7568 1554752 IFLab1_000240 CC(=O)Nc1nc(c(s1)C(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K21 compound treatment 0.348 -0.00546 -0.21 0.318 -0.0348 -0.73 -0.6669 -0.8781 1482437 IFLab1_000241 CC(=O)Nc1ccc2nc(NC(=O)C(C)(C)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K22 compound treatment 0.351 -0.00246 -0.1 0.321 -0.0318 -0.67 -0.5391 -0.8014 1251197 IFLab1_000242 CCc1cc(C(=O)Cc2ccc3ccccc3n2)c(O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K23 mock treatment 0.326 -0.0275 -1.08 0.326 -0.0268 -0.56 -1.1602 -0.9535 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 K24 mock treatment 0.085 -0.268 -10.56 0.086 -0.267 -5.58 -11.4117 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L01 compound treatment 0.366 0.0125 0.49 0.344 -0.00881 -0.18 0.2183 0.4147 2065969 IFLab1_000243 CN(C)c1oc(C)nc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L02 compound treatment 0.341 -0.0125 -0.49 0.35 -0.00281 -0.06 -0.388 -0.7864 1438167 IFLab1_000244 COc1ccc(cc1)C(=O)CSc2nc3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L03 compound treatment 0.329 -0.0245 -0.96 0.332 -0.0208 -0.44 -0.988 -0.9358 2065970 IFLab1_000245 COC(=O)c1nc(oc1N(C)C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L04 compound treatment 0.332 -0.0215 -0.84 0.343 -0.00981 -0.21 -0.7418 -0.8542 1432807 IFLab1_000246 CC(C)C1CCC(C)CC1OCC(O)CN2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L05 compound treatment 0.333 -0.0205 -0.8 0.343 -0.00981 -0.21 -0.714 -0.86 1715518 IFLab1_000247 CCc1sc(N)nc1c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L06 compound treatment 0.33 -0.0235 -0.92 0.334 -0.0188 -0.39 -0.9306 -0.9279 2065971 IFLab1_000248 OC(=O)CSc1cccc2cccc(C(=O)O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L07 compound treatment 0.352 -0.00146 -0.06 0.339 -0.0138 -0.29 -0.2449 -0.8313 2065972 IFLab1_000249 C1CCN=C(CC1)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L08 compound treatment 0.34 -0.0135 -0.53 0.336 -0.0168 -0.35 -0.623 -0.9803 1472187 IFLab1_000250 CCOC(=O)c1csc(NC(=O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L09 compound treatment 0.344 -0.00946 -0.37 0.348 -0.00481 -0.1 -0.3342 -0.8673 1077649 IFLab1_000251 O=C(c1ccccc1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L10 compound treatment 0.352 -0.00146 -0.06 0.351 -0.00181 -0.04 -0.0674 -0.9797 1543700 IFLab1_000252 CSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L11 compound treatment 0.354 5.41E-4 0.02 0.351 -0.00181 -0.04 -0.0118 -0.2708 1920684 IFLab1_000253 Nc1cc(ccc1C(=O)O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L12 compound treatment 0.329 -0.0245 -0.96 0.359 0.00619 0.13 -0.5884 -0.6064 1209783 IFLab1_000254 ONC(=O)C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L13 compound treatment 0.348 -0.00546 -0.21 0.349 -0.00381 -0.08 -0.2082 -0.9091 2065973 IFLab1_000255 Oc1ccc(Br)cc1/C=[N+](\[O-])/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L14 compound treatment 0.331 -0.0225 -0.88 0.343 -0.00981 -0.21 -0.7696 -0.8489 2065974 IFLab1_000256 COc1ccc(/C=N/C2=NNC(=CS2)c3ccc(OC)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L15 compound treatment 0.343 -0.0105 -0.41 0.362 0.00919 0.19 -0.1548 -0.341 2065975 IFLab1_000257 Oc1ccccc1C2=Nc3ccccc3NC(=C2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L16 compound treatment 0.339 -0.0145 -0.57 0.351 -0.00181 -0.04 -0.4288 -0.7526 2065976 IFLab1_000258 c1c(sc2nc3ccccc3n12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L17 compound treatment 0.348 -0.00546 -0.21 0.346 -0.00681 -0.14 -0.2526 -0.9802 2065977 IFLab1_000259 ClC1(CC2CC3C1)CC(C2)(C3)C(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L18 compound treatment 0.338 -0.0155 -0.61 0.321 -0.0318 -0.67 -0.9005 -0.999 1565649 IFLab1_000260 Fc1ccc(cc1)C2NCCc3nc[nH]c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L19 compound treatment 0.349 -0.00446 -0.18 0.349 -0.00381 -0.08 -0.1804 -0.9364 1181085 IFLab1_000261 Clc1ccc(cc1Cl)S(=O)(=O)N2CCn3c(C2)nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L20 compound treatment 0.347 -0.00646 -0.25 0.339 -0.0138 -0.29 -0.3839 -0.9979 2065978 IFLab1_000262 O=C(N/C(=C/c1cccs1)/C(=O)N2CCCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L21 compound treatment 0.343 -0.0105 -0.41 0.339 -0.0138 -0.29 -0.4952 -0.9851 1005863 IFLab1_000263 c1ccc(cc1)c2nn(c3ccccc3)[n+](n2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L22 compound treatment 0.34 -0.0135 -0.53 0.321 -0.0318 -0.67 -0.8449 -0.9935 1133625 IFLab1_000264 Clc1c(sc2ccccc12)C(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L23 mock treatment 0.327 -0.0265 -1.04 0.328 -0.0248 -0.52 -1.1028 -0.9484 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 L24 mock treatment 0.086 -0.267 -10.52 0.088 -0.265 -5.54 -11.3543 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M01 compound treatment 0.341 -0.0125 -0.49 0.336 -0.0168 -0.35 -0.5951 -0.9868 1077797 IFLab1_000265 OC1(CC(=O)c2ccccc2)C(=O)Nc3ccccc31 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M02 compound treatment 0.346 -0.00746 -0.29 0.356 0.00319 0.07 -0.1602 -0.5326 2065979 IFLab1_000266 N=C1N(Cc2ccccc12)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M03 compound treatment 0.34 -0.0135 -0.53 0.349 -0.00381 -0.08 -0.4306 -0.8046 1274778 IFLab1_000267 Cc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M04 compound treatment 0.33 -0.0235 -0.92 0.328 -0.0248 -0.52 -1.0193 -0.963 2065980 IFLab1_000268 CC(C)C(=O)Nc1nc2ccc(Cl)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M05 compound treatment 0.321 -0.0325 -1.28 0.345 -0.00781 -0.16 -1.018 -0.7912 1248780 IFLab1_000269 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M06 compound treatment 0.35 -0.00346 -0.14 0.353 1.89E-4 0.0 -0.0934 -0.6862 1352995 IFLab1_000270 CC(C)C(=O)Nc1ccccc1c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M07 compound treatment 0.333 -0.0205 -0.8 0.332 -0.0208 -0.44 -0.8768 -0.9585 1123586 IFLab1_000271 COc1ccc(cc1)C(=O)N=c2[nH]c3CCC(C)Cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M08 compound treatment 0.325 -0.0285 -1.12 0.356 0.00319 0.07 -0.744 -0.6638 1136362 IFLab1_000272 O=C(CSc1nc2ccccc2o1)OCC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M09 compound treatment 0.337 -0.0165 -0.65 0.332 -0.0208 -0.44 -0.7655 -0.9814 1169709 IFLab1_000273 COc1ccc(C(=O)N=c2[nH]c(cs2)c3ccc(C)cc3)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M10 compound treatment 0.351 -0.00246 -0.1 0.336 -0.0168 -0.35 -0.3171 -0.8692 1378300 IFLab1_000274 CCOc1cccc2sc(NC(=O)CC)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M11 compound treatment 0.336 -0.0175 -0.69 0.357 0.00419 0.09 -0.4234 -0.6118 1648536 IFLab1_000275 O=C(N=c1[nH]c(cs1)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M12 compound treatment 0.343 -0.0105 -0.41 0.334 -0.0188 -0.39 -0.5691 -0.9998 1115780 IFLab1_000276 CCOC(=O)c1nc[nH]c1C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M13 compound treatment 0.345 -0.00846 -0.33 0.348 -0.00481 -0.1 -0.3064 -0.8816 1122531 IFLab1_000277 Oc1ccc(cc1)N2C(=O)c3cccc4cccc(C2=O)c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M14 compound treatment 0.326 -0.0275 -1.08 0.346 -0.00681 -0.14 -0.8642 -0.7936 1349436 IFLab1_000278 OCCN=c1scc(c2ccc(Br)cc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M15 compound treatment 0.354 5.41E-4 0.02 0.355 0.00219 0.05 0.0474 0.939 2065981 IFLab1_000279 Nc1ccc(Br)cc1C(NCC(=O)O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M16 compound treatment 0.344 -0.00946 -0.37 0.355 0.00219 0.05 -0.2306 -0.6154 2065982 IFLab1_000280 CCOC(=O)CSc1ncc([nH]1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M17 compound treatment 0.332 -0.0215 -0.84 0.342 -0.0108 -0.23 -0.7566 -0.8661 2065983 IFLab1_000281 CCc1nnc(NC(=O)/C=C/c2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M18 compound treatment 0.335 -0.0185 -0.73 0.353 1.89E-4 0.0 -0.5104 -0.7032 1402099 IFLab1_000282 CC(=O)Nc1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M19 compound treatment 0.35 -0.00346 -0.14 0.338 -0.0148 -0.31 -0.3153 -0.9317 1334707 IFLab1_000283 Cc1ccc2[nH]c(=NC(=O)c3ccc(F)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M20 compound treatment 0.343 -0.0105 -0.41 0.343 -0.00981 -0.21 -0.436 -0.9485 1173878 IFLab1_000284 CC(C)C(=O)Nc1nc(c(s1)C(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M21 compound treatment 0.358 0.00454 0.18 0.36 0.00719 0.15 0.2326 0.9964 1399425 IFLab1_000285 CC(=O)Nc1ccc2nc(NC(=O)c3ccc(F)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M22 compound treatment 0.347 -0.00646 -0.25 0.338 -0.0148 -0.31 -0.3987 -0.9951 1173147 IFLab1_000286 Cc1nc(cs1)c2coc3cc(OCC(=O)O)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M23 mock treatment 0.297 -0.0565 -2.22 0.334 -0.0188 -0.39 -1.848 -0.8197 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 M24 mock treatment 0.088 -0.265 -10.44 0.09 -0.263 -5.5 -11.2691 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N01 compound treatment 0.341 -0.0125 -0.49 0.339 -0.0138 -0.29 -0.5508 -0.9683 1261092 IFLab1_000287 COc1nc(C#N)c(o1)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N02 compound treatment 0.343 -0.0105 -0.41 0.345 -0.00781 -0.16 -0.4064 -0.9183 1016465 IFLab1_000288 O=S(=O)(N1CCN(CC1)S(=O)(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N03 compound treatment 0.346 -0.00746 -0.29 0.333 -0.0198 -0.41 -0.5005 -0.9856 1147410 IFLab1_000289 CNc1oc(nc1S(=O)(=O)c2ccc(C)cc2)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N04 compound treatment 0.342 -0.0115 -0.45 0.354 0.00119 0.02 -0.301 -0.667 1252245 IFLab1_000290 CC1CN(CC(O)COCc2ccccc2)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N05 compound treatment 0.336 -0.0175 -0.69 0.35 -0.00281 -0.06 -0.527 -0.7649 1056492 IFLab1_000291 O=C(CSc1nc2ccccc2s1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N06 compound treatment 0.36 0.00654 0.26 0.356 0.00319 0.07 0.229 0.8621 2065984 IFLab1_000292 COc1c2ccccc2c(OC)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N07 compound treatment 0.363 0.00954 0.38 0.351 -0.00181 -0.04 0.2385 0.6325 2065985 IFLab1_000293 C1CCN/C(=N\c2ccc(/N=C\3/CCCCCN3)cc2)/CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N08 compound treatment 0.331 -0.0225 -0.88 0.346 -0.00681 -0.14 -0.7252 -0.8107 2065986 IFLab1_000294 CCOC(=O)c1csc(NC(=O)CC)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N09 compound treatment 0.323 -0.0305 -1.2 0.321 -0.0318 -0.67 -1.3175 -0.9616 1303815 IFLab1_000295 CCNC(=O)OCCC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N10 compound treatment 0.354 5.41E-4 0.02 0.365 0.0122 0.26 0.1954 0.7634 1343698 IFLab1_000296 O=S(=O)(N1CCOCC1)c2ccc(cc2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N11 compound treatment 0.337 -0.0165 -0.65 0.355 0.00219 0.05 -0.4252 -0.6554 2065987 IFLab1_000297 CCc1cc(CC)c(/C=N/O)c(CC)c1/C=N/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N12 compound treatment 0.359 0.00554 0.22 0.355 0.00219 0.05 0.1864 0.8375 1689360 IFLab1_000298 CCCNC1C2CC3CC(C2)CC1C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N13 compound treatment 0.329 -0.0245 -0.96 0.316 -0.0368 -0.77 -1.2247 -0.994 2065988 IFLab1_000299 [O-]/[N+](=C\c1cccc(Br)c1)/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N14 compound treatment 0.356 0.00254 0.1 0.353 1.89E-4 0.0 0.0734 0.7346 1257989 IFLab1_000300 COc1c(nc2ccccn12)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N15 compound treatment 0.353 -4.59E-4 -0.02 0.351 -0.00181 -0.04 -0.0396 -0.9426 1515635 IFLab1_000301 CC(C)(C)NC(=O)CC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N16 compound treatment 0.344 -0.00946 -0.37 0.346 -0.00681 -0.14 -0.3638 -0.9133 2065989 IFLab1_000302 OC(=O)C1Cc2nc[nH]c2C(N1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N17 compound treatment 0.325 -0.0285 -1.12 0.348 -0.00481 -0.1 -0.8624 -0.7676 2065990 IFLab1_000303 CCN(CC)C(=O)C1(CC2CC3CC(Cl)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N18 compound treatment 0.351 -0.00246 -0.1 0.352 -8.11E-4 -0.02 -0.0804 -0.8187 2065991 IFLab1_000304 COc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)N3CCCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N19 compound treatment 0.368 0.0145 0.57 0.341 -0.0118 -0.25 0.2295 0.3685 1344908 IFLab1_000305 Brc1ccc2[nH]c3nc(SCCN4CCOCC4)nnc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N20 compound treatment 0.359 0.00554 0.22 0.344 -0.00881 -0.18 0.0237 0.0829 2065992 IFLab1_000306 Cc1ccc(cc1)C(=O)N/C(=C/c2cccs2)/C(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N21 compound treatment 0.415 0.0615 2.42 0.414 0.0612 1.28 2.6164 0.9557 2065993 IFLab1_000307 Oc1ccccc1/C=C\2/SC(=S)N(CC=C)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N22 compound treatment 0.326 -0.0275 -1.08 0.321 -0.0318 -0.67 -1.2341 -0.973 2065994 IFLab1_000308 CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N23 mock treatment 0.33 -0.0235 -0.92 0.331 -0.0218 -0.46 -0.975 -0.9474 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 N24 mock treatment 0.1 -0.253 -9.97 0.091 -0.262 -5.48 -10.9207 -0.9603 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O01 compound treatment 0.345 -0.00846 -0.33 0.33 -0.0228 -0.48 -0.5727 -0.9844 1335173 IFLab1_000309 O=C(Nc1ccccc1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O02 compound treatment 0.341 -0.0125 -0.49 0.344 -0.00881 -0.18 -0.4768 -0.9109 2065995 IFLab1_000310 OC(=O)c1cc(ccc1O)N2Cc3ccccc3C2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O03 compound treatment 0.352 -0.00146 -0.06 0.355 0.00219 0.05 -0.0082 -0.1114 1153397 IFLab1_000311 COc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O04 compound treatment 0.367 0.0135 0.53 0.377 0.0242 0.51 0.7344 0.9997 2065996 IFLab1_000312 Clc1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O05 compound treatment 0.372 0.0185 0.73 0.363 0.0102 0.21 0.6662 0.8772 1740717 IFLab1_000313 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3CCCCc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O06 compound treatment 0.423 0.0695 2.73 0.405 0.0522 1.09 2.7056 0.919 1547719 IFLab1_000314 COc1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O07 compound treatment 0.356 0.00254 0.1 0.35 -0.00281 -0.06 0.029 0.2505 1154542 IFLab1_000315 CC(=O)N=c1[nH]c(cs1)c2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O08 compound treatment 0.338 -0.0155 -0.61 0.346 -0.00681 -0.14 -0.5306 -0.8499 1421349 IFLab1_000316 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O09 compound treatment 0.338 -0.0155 -0.61 0.348 -0.00481 -0.1 -0.501 -0.8131 1183972 IFLab1_000317 Clc1ccc2[nH]c(=NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O10 compound treatment 0.334 -0.0195 -0.77 0.345 -0.00781 -0.16 -0.6566 -0.8392 1507719 IFLab1_000318 CCOc1cccc2sc(NC(=O)c3ccccc3F)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O11 compound treatment 0.347 -0.00646 -0.25 0.339 -0.0138 -0.29 -0.3839 -0.9979 1262170 IFLab1_000319 O=C(N=c1[nH]c(cs1)c2ccccc2)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O12 compound treatment 0.353 -4.59E-4 -0.02 0.351 -0.00181 -0.04 -0.0396 -0.9426 1442046 IFLab1_000320 Clc1ccc2nc(nc(c3ccccc3)c2c1)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O13 compound treatment 0.357 0.00354 0.14 0.349 -0.00381 -0.08 0.042 0.2621 2065997 IFLab1_000321 OC(=O)CCCNc1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O14 compound treatment 0.357 0.00354 0.14 0.353 1.89E-4 0.0 0.1012 0.7269 1508834 IFLab1_000322 Cc1ccc(C)c(NCC(O)c2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O15 compound treatment 0.347 -0.00646 -0.25 0.352 -8.11E-4 -0.02 -0.1916 -0.7527 2065998 IFLab1_000323 COC(=O)CNC(c1ccccc1)c2cc(C)ccc2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O16 compound treatment 0.352 -0.00146 -0.06 0.327 -0.0258 -0.54 -0.4225 -0.7779 2065999 IFLab1_000324 C(c1nnc2CCCCCn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O17 compound treatment 0.35 -0.00346 -0.14 0.344 -0.00881 -0.18 -0.2266 -0.9888 2066000 IFLab1_000325 CC(C)c1nnc(NC(=O)C(C)(C)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O18 compound treatment 0.342 -0.0115 -0.45 0.345 -0.00781 -0.16 -0.4342 -0.9059 1270129 IFLab1_000326 CCOC(=O)c1sc(N)nc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O19 compound treatment 0.349 -0.00446 -0.18 0.339 -0.0138 -0.29 -0.3283 -0.9713 1513067 IFLab1_000327 COc1cc(cc(OC)c1OC)C(=O)N=c2[nH]c3ccc(C)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O20 compound treatment 0.348 -0.00546 -0.21 0.326 -0.0268 -0.56 -0.5485 -0.9131 1260925 IFLab1_000328 CC(=O)N1CC(=O)Nc2ccc(C)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O21 compound treatment 0.349 -0.00446 -0.18 0.344 -0.00881 -0.18 -0.2544 -0.9997 1197138 IFLab1_000329 COc1cc2ccccc2cc1C(=O)Nc3ccc(F)cc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O22 compound treatment 0.347 -0.00646 -0.25 0.344 -0.00881 -0.18 -0.31 -0.9876 1016782 IFLab1_000330 C1CCN(CC1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O23 mock treatment 0.326 -0.0275 -1.08 0.33 -0.0228 -0.48 -1.101 -0.9326 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 O24 mock treatment 0.092 -0.261 -10.28 0.093 -0.26 -5.44 -11.1135 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P01 mock treatment 0.328 -0.0255 -1.0 0.342 -0.0108 -0.23 -0.8678 -0.8456 2066001 IFLab1_000331 CN(C)c1oc(nc1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P02 mock treatment 0.341 -0.0125 -0.49 0.345 -0.00781 -0.16 -0.462 -0.8946 1010311 IFLab1_000332 C(N1CCN(Cc2ccccc2)CC1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P03 mock treatment 0.346 -0.00746 -0.29 0.352 -8.11E-4 -0.02 -0.2194 -0.7468 1170580 IFLab1_000333 CN(C)c1oc(C)nc1S(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P04 mock treatment 0.362 0.00854 0.34 0.362 0.00919 0.19 0.3734 0.965 2066002 IFLab1_000334 OC(COCCC1(CC2CC3CC(C2)C1)C3)CN4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P05 mock treatment 0.374 0.0205 0.81 0.374 0.0212 0.44 0.8846 0.9601 2066003 IFLab1_000335 COc1ccc(NC2=NCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P06 mock treatment 0.368 0.0145 0.57 0.376 0.0232 0.49 0.7474 0.9967 2066004 IFLab1_000336 CCc1ccc(OC(=O)c2ccc(Br)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P07 mock treatment 0.397 0.0435 1.71 0.383 0.0302 0.63 1.6572 0.9082 1422847 IFLab1_000337 O=S1(=O)CC(Nc2ccccc2)C=C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P08 mock treatment 0.397 0.0435 1.71 0.385 0.0322 0.67 1.6868 0.9169 2066005 IFLab1_000338 CCOC(=O)c1csc(NC(=O)C)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P09 mock treatment 0.381 0.0275 1.08 0.387 0.0342 0.72 1.2716 0.9798 1101861 IFLab1_000339 FC(F)(F)C(=O)NC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P10 mock treatment 0.383 0.0295 1.16 0.374 0.0212 0.44 1.1348 0.9128 1587082 IFLab1_000340 CCN(CC)S(=O)(=O)c1ccc(cc1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P11 mock treatment 0.414 0.0605 2.38 0.414 0.0612 1.28 2.5886 0.9577 1046807 IFLab1_000341 OC(=O)CNc1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P12 mock treatment 0.392 0.0385 1.52 0.389 0.0362 0.76 1.607 0.9486 1308973 IFLab1_000342 CC(C)(C)C(=O)NC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P13 mock treatment 0.401 0.0475 1.87 0.37 0.0172 0.36 1.5761 0.828 2066006 IFLab1_000343 OC(=O)/C=C/C(=O)Nc1ccc(cc1)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P14 mock treatment 0.399 0.0455 1.79 0.38 0.0272 0.57 1.6684 0.888 2066007 IFLab1_000344 O/C(=N\c1ccccc1)/Nc2ccc(Cl)c(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P15 mock treatment 0.372 0.0185 0.73 0.371 0.0182 0.38 0.7846 0.9541 1578265 IFLab1_000345 OC(=O)C1CC2CC3CC(C2)CC1(O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P16 mock treatment 0.378 0.0245 0.96 0.385 0.0322 0.67 1.1586 0.9846 1712628 IFLab1_000346 Brc1ccc(OCC(=O)OC2CCS(=O)(=O)C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P17 mock treatment 0.37 0.0165 0.65 0.369 0.0162 0.34 0.6994 0.9538 2066008 IFLab1_000347 NC(=O)C1(CC2CC3CC(Cl)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P18 mock treatment 0.368 0.0145 0.57 0.367 0.0142 0.3 0.6142 0.9534 2066009 IFLab1_000348 Cc1ccc(cc1)C(=O)N/C(=C/c2ccco2)/C(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P19 mock treatment 0.371 0.0175 0.69 0.368 0.0152 0.32 0.7124 0.9382 1547979 IFLab1_000349 Nc1ccccc1c2nc3cc4ccccc4cc3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P20 mock treatment 0.349 -0.00446 -0.18 0.364 0.0112 0.23 0.0416 0.1422 2066010 IFLab1_000350 CC1CCN(CC1)C(=O)/C(=C\c2ccccc2)/NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P21 mock treatment 0.368 0.0145 0.57 0.357 0.00419 0.09 0.4662 0.8061 2066011 IFLab1_000351 COc1ccc(/N=C/2\CCCCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P22 mock treatment 0.357 0.00354 0.14 0.355 0.00219 0.05 0.1308 0.8927 2066012 IFLab1_000352 CC1(C)C(C=C(Cl)Cl)C1C(=O)NC2CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P23 positive control 0.343 -0.0105 -0.41 0.337 -0.0158 -0.33 -0.5247 -0.9942 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1412 P24 positive control 0.093 -0.26 -10.24 0.098 -0.255 -5.33 -11.0118 -0.9537 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A01 compound treatment 0.344 0.0171 0.67 0.342 0.0154 0.32 0.7028 0.9439 2066013 IFLab1_000353 CC1(C)C(C=C(Cl)Cl)C1C(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A02 compound treatment 0.341 0.0141 0.55 0.315 -0.0116 -0.24 0.2199 0.3643 1254934 IFLab1_000354 COc1cccc(OCC(=O)Oc2ccc(C#N)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A03 compound treatment 0.321 -0.00594 -0.23 0.338 0.0114 0.24 0.0042 0.0125 2066014 IFLab1_000355 Cc1cc(C)nc(SCc2nc3ncccn3c2Br)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A04 compound treatment 0.334 0.00706 0.28 0.323 -0.00356 -0.07 0.1436 0.4996 2066015 IFLab1_000356 N=C1NC(=O)C(CC(=O)NCc2ccccc2)S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A05 compound treatment 0.315 -0.0119 -0.47 0.313 -0.0136 -0.28 -0.5326 -0.971 1318533 IFLab1_000357 Nc1nc(cs1)c2ccc(Oc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A06 compound treatment 0.321 -0.00594 -0.23 0.311 -0.0156 -0.33 -0.3954 -0.9867 2066016 IFLab1_000358 Cc1ccc2nc(NC(=O)c3ccc(Br)s3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A07 compound treatment 0.341 0.0141 0.55 0.332 0.00544 0.11 0.4714 0.8351 1556775 IFLab1_000359 COc1ccc2oc(=O)c(cc2c1)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A08 compound treatment 0.302 -0.0249 -0.98 0.341 0.0144 0.3 -0.4797 -0.4675 1685499 IFLab1_000360 Cc1cccc2nc(COc3ccc(Cl)cc3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A09 compound treatment 0.321 -0.00594 -0.23 0.331 0.00444 0.09 -0.0994 -0.3957 1644755 IFLab1_000361 Cc1ccn2cc(nc2c1)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A10 compound treatment 0.324 -0.00294 -0.12 0.335 0.00844 0.18 0.0432 0.2047 1919680 IFLab1_000362 O/N=C/c1ccc(o1)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A11 compound treatment 0.324 -0.00294 -0.12 0.327 4.38E-4 0.01 -0.0752 -0.649 1663537 IFLab1_000363 CCN(CC)CC(O)COc1ccc(OC)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A12 compound treatment 0.328 0.00106 0.04 0.336 0.00944 0.2 0.1692 0.8381 2066017 IFLab1_000364 Cc1cc(C)nc(SCNC(=O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A13 compound treatment 0.303 -0.0239 -0.94 0.303 -0.0236 -0.49 -1.0142 -0.9545 1576829 IFLab1_000365 CC(C)NCC(O)COc1ccc(cc1)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A14 compound treatment 0.372 0.0451 1.77 0.382 0.0554 1.16 2.0731 0.9789 1710436 IFLab1_000366 CC1(C)CC(=O)c2sc(NC(=O)c3cccs3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A15 compound treatment 0.318 -0.00894 -0.35 0.324 -0.00256 -0.05 -0.2864 -0.8057 1232209 IFLab1_000367 COc1ccc(Cc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A16 compound treatment 0.321 -0.00594 -0.23 0.344 0.0174 0.36 0.093 0.2146 2066018 IFLab1_000368 CCOC(=O)CSc1nc(C)cc(O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A17 compound treatment 0.346 0.0191 0.75 0.325 -0.00156 -0.03 0.5069 0.6756 2066019 IFLab1_000369 FC(F)(F)C(=O)NC(=O)Oc1ccc(Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A18 compound treatment 0.326 -9.37E-4 -0.04 0.329 0.00244 0.05 0.01 0.159 2066020 IFLab1_000370 COc1ccc(cc1)c2cc(C)nc(SCC(=O)Nc3ccccc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A19 compound treatment 0.323 -0.00394 -0.15 0.339 0.0124 0.26 0.0746 0.2462 1116045 IFLab1_000371 CC(=O)NC1(CCCCC1)C2CCCCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A20 compound treatment 0.342 0.0151 0.59 0.325 -0.00156 -0.03 0.3956 0.6671 1391769 IFLab1_000372 Clc1ccccc1C(=O)Nc2nc(=S)ss2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A21 compound treatment 0.347 0.0201 0.79 0.322 -0.00456 -0.1 0.4903 0.617 1482648 IFLab1_000373 CC1CCc2sc(NC(=O)c3cccs3)c(C#N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A22 compound treatment 0.321 -0.00594 -0.23 0.339 0.0124 0.26 0.019 0.0542 1082368 IFLab1_000374 NC(=N)SC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A23 mock treatment 0.318 -0.00894 -0.35 0.319 -0.00756 -0.16 -0.3604 -0.9351 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 A24 positive control 0.078 -0.249 -9.79 0.078 -0.249 -5.2 -10.599 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B01 compound treatment 0.337 0.0101 0.4 0.331 0.00444 0.09 0.3454 0.85 1400599 IFLab1_000375 COc1ccc(c2nnc(NC(=O)c3ccccc3C)s2)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B02 compound treatment 0.33 0.00306 0.12 0.346 0.0194 0.41 0.3728 0.8787 1655412 IFLab1_000376 CC(C)Oc1ccc(c2n[nH]cc2c3ccc(F)cc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B03 compound treatment 0.331 0.00406 0.16 0.318 -0.00856 -0.18 -0.0138 -0.0573 1427798 IFLab1_000377 O=c1oc2ccccc2cc1c3nc4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B04 compound treatment 0.323 -0.00394 -0.15 0.342 0.0154 0.32 0.119 0.3321 2066021 IFLab1_000378 COc1ccc2c(=O)c(coc2c1)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B05 compound treatment 0.329 0.00206 0.08 0.32 -0.00656 -0.14 -0.0398 -0.2493 1264650 IFLab1_000379 CCc1ccc(cc1)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B06 compound treatment 0.339 0.0121 0.47 0.347 0.0204 0.43 0.6378 0.9987 1357504 IFLab1_000380 CCCCc1cc(C(=O)Cc2ccccn2)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B07 compound treatment 0.327 6.25E-5 0.0 0.321 -0.00556 -0.12 -0.0806 -0.692 1595739 IFLab1_000381 CCc1ccc(cc1)S(=O)(=O)Nc2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B08 compound treatment 0.35 0.0231 0.91 0.354 0.0274 0.57 1.0472 0.9757 1475722 IFLab1_000382 CCc1cc2c(=O)c(coc2cc1O)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B09 compound treatment 0.336 0.00906 0.36 0.337 0.0104 0.22 0.4064 0.9724 1674860 IFLab1_000383 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(OCc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B10 compound treatment 0.347 0.0201 0.79 0.36 0.0334 0.7 1.0526 0.9982 1245387 IFLab1_000384 CCc1cc2c(=O)c(coc2cc1O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B11 compound treatment 0.321 -0.00594 -0.23 0.322 -0.00456 -0.1 -0.2326 -0.9222 2066022 IFLab1_000385 CC1C(=C(N)OC2=C1C(=O)CC(C2)c3ccccc3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B12 compound treatment 0.336 0.00906 0.36 0.34 0.0134 0.28 0.4508 0.9931 1618011 IFLab1_000386 CCCc1cc2c(=O)c(c(C)oc2cc1OC(=O)C)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B13 compound treatment 0.331 0.00406 0.16 0.334 0.00744 0.16 0.223 0.9999 2066023 IFLab1_000387 Clc1ccc(s1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B14 compound treatment 0.333 0.00606 0.24 0.337 0.0104 0.22 0.323 0.999 1478672 IFLab1_000388 Oc1ccc2c(=O)c(coc2c1)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B15 compound treatment 0.315 -0.0119 -0.47 0.314 -0.0126 -0.26 -0.5178 -0.9625 1196124 IFLab1_000389 Cc1cc(O)cc2occ(c3cnn(c3)c4ccccc4)c(=O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B16 compound treatment 0.373 0.0461 1.81 0.363 0.0364 0.76 1.8198 0.9261 1450229 IFLab1_000390 O=C(Nc1ncc(Cc2ccccc2)s1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B17 compound treatment 0.313 -0.0139 -0.55 0.335 0.00844 0.18 -0.2626 -0.4562 1597678 IFLab1_000391 Clc1cc(CC#N)c2OCOCc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B18 compound treatment 0.321 -0.00594 -0.23 0.319 -0.00756 -0.16 -0.277 -0.9821 2066024 IFLab1_000392 O=C/1Nc2ccccc2\C1=C/3\SC(=S)N(C3=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B19 compound treatment 0.337 0.0101 0.4 0.341 0.0144 0.3 0.4934 0.9911 1462039 IFLab1_000393 CCCc1cc2c(=O)c(coc2cc1O)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B20 compound treatment 0.458 0.131 5.15 0.447 0.12 2.52 5.4259 0.9459 2066025 IFLab1_000394 OC(=O)CCCN1C(=O)/C(=C/c2ccccc2C(=O)O)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B21 compound treatment 0.333 0.00606 0.24 0.333 0.00644 0.13 0.2638 0.9635 1219702 IFLab1_000395 Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B22 compound treatment 0.335 0.00806 0.32 0.335 0.00844 0.18 0.349 0.9618 2066026 IFLab1_000396 CCN(CC)C(=O)CN1C(=O)S/C(=C\c2ccccc2)/C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B23 mock treatment 0.328 0.00106 0.04 0.328 0.00144 0.03 0.0508 0.987 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 B24 positive control 0.077 -0.25 -9.83 0.077 -0.25 -5.22 -10.6416 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C01 compound treatment 0.334 0.00706 0.28 0.323 -0.00356 -0.07 0.1436 0.4996 2066027 IFLab1_000397 CC1(C)C(C=C(Cl)Cl)C1C(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C02 compound treatment 0.321 -0.00594 -0.23 0.327 4.38E-4 0.01 -0.1586 -0.6789 1281656 IFLab1_000398 COc1cccc(OCC(=O)NCc2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C03 compound treatment 0.331 0.00406 0.16 0.342 0.0154 0.32 0.3414 0.9473 1574522 IFLab1_000399 Cc1cc(C)n2cc(CSc3nc4ccccc4[nH]3)nc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C04 compound treatment 0.335 0.00806 0.32 0.345 0.0184 0.39 0.497 0.9952 1122062 IFLab1_000400 O=C(Cc1ccccc1)Nc2ccc(cc2)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C05 compound treatment 0.324 -0.00294 -0.12 0.339 0.0124 0.26 0.1024 0.3595 1458550 IFLab1_000401 CC(NC(=O)C1(CC2CC3C1)CC(C2)(C3)c4ccc(C)cc4)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C06 compound treatment 0.331 0.00406 0.16 0.342 0.0154 0.32 0.3414 0.9473 2066028 IFLab1_000402 Brc1ccc(s1)C(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C07 compound treatment 0.332 0.00506 0.2 0.334 0.00744 0.16 0.2508 0.9926 1569865 IFLab1_000403 Brc1ccc2oc(=O)c(cc2c1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C08 compound treatment 0.332 0.00506 0.2 0.341 0.0144 0.3 0.3544 0.9795 2066029 IFLab1_000404 O=C(OCc1nc2ccccc2s1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C09 compound treatment 0.367 0.0401 1.58 0.385 0.0584 1.22 1.9785 0.9922 2066030 IFLab1_000405 c1csc(c1)c2cc3ccccn3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C10 compound treatment 0.337 0.0101 0.4 0.337 0.0104 0.22 0.4342 0.9608 1576056 IFLab1_000406 OC(NC(=O)c1ccco1)C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C11 compound treatment 0.335 0.00806 0.32 0.332 0.00544 0.11 0.3046 0.9044 1540776 IFLab1_000407 CCCc1ccc(OCC(O)CN2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C12 compound treatment 0.322 -0.00494 -0.19 0.328 0.00144 0.03 -0.116 -0.5905 1916230 IFLab1_000408 CC(C)(C)C(=O)NC(=C(Cl)Cl)Sc1nccc(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C13 compound treatment 0.336 0.00906 0.36 0.332 0.00544 0.11 0.3324 0.8887 1373755 IFLab1_000409 CCC(=O)NCC(=O)Nc1ccc(Br)cc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C14 compound treatment 0.329 0.00206 0.08 0.334 0.00744 0.16 0.1674 0.9538 2066031 IFLab1_000410 CSc1nc2ccc(NC(=O)c3ccc(Cl)s3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C15 compound treatment 0.342 0.0151 0.59 0.34 0.0134 0.28 0.6176 0.9421 1983522 IFLab1_000411 CC(C)C(=O)c1ccc(OCCOc2ccc(C#N)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C16 compound treatment 0.341 0.0141 0.55 0.35 0.0234 0.49 0.7378 0.9982 2066032 IFLab1_000412 O=C(CSc1ncnc2ccccc12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C17 compound treatment 0.379 0.0521 2.05 0.377 0.0504 1.06 2.1938 0.9525 1156224 IFLab1_000413 CCOC(=O)Cn1c(=O)c(nc2ccccc12)c3ccccc3N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C18 compound treatment 0.336 0.00906 0.36 0.337 0.0104 0.22 0.4064 0.9724 1591580 IFLab1_000414 Cc1cc(nc(SCC(=O)N2CCCC2)n1)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C19 compound treatment 0.478 0.151 5.94 0.491 0.164 3.44 6.633 0.9663 2066033 IFLab1_000415 CCOc1cc(/C=C\2/SC(=S)NC2=O)cc(Br)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C20 compound treatment 0.335 0.00806 0.32 0.336 0.00944 0.2 0.3638 0.9741 1222761 IFLab1_000416 CCOC(=O)c1sc2nc(C)c(C)c(C)c2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C21 compound treatment 0.314 -0.0129 -0.51 0.326 -5.62E-4 -0.01 -0.368 -0.7233 2066034 IFLab1_000417 COc1ccc(cc1)N2C(c3ccccc3)C(F)(F)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C22 compound treatment 0.332 0.00506 0.2 0.334 0.00744 0.16 0.2508 0.9926 2066035 IFLab1_000418 C1CSC(=NC1)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C23 mock treatment 0.329 0.00206 0.08 0.324 -0.00256 -0.05 0.0194 0.1998 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 C24 positive control 0.078 -0.249 -9.79 0.079 -0.248 -5.18 -10.5842 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D01 compound treatment 0.363 0.0361 1.42 0.374 0.0474 0.99 1.7045 0.9848 1429941 IFLab1_000419 Cc1ccccc1c2nnc(NC(=O)c3ccccc3Cl)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D02 compound treatment 0.332 0.00506 0.2 0.325 -0.00156 -0.03 0.1176 0.5831 1174306 IFLab1_000420 Oc1ccc(C(=O)Cc2cscn2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D03 compound treatment 0.345 0.0181 0.71 0.325 -0.00156 -0.03 0.4791 0.6738 1207536 IFLab1_000421 Brc1ccc2oc(=O)c(cc2c1)c3nnc(o3)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D04 compound treatment 0.338 0.0111 0.43 0.352 0.0254 0.53 0.684 0.995 2066036 IFLab1_000422 Oc1ccc2c(=O)c(coc2c1)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D05 compound treatment 0.336 0.00906 0.36 0.337 0.0104 0.22 0.4064 0.9724 1494557 IFLab1_000423 O=S(=O)(CCc1ccccc1)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D06 compound treatment 0.351 0.0241 0.95 0.37 0.0434 0.91 1.3117 0.9998 1550716 IFLab1_000424 Cc1cc(O)c(C(=O)Cc2ccccn2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D07 compound treatment 0.326 -9.37E-4 -0.04 0.341 0.0144 0.3 0.1876 0.6163 1383245 IFLab1_000425 CC(=O)Nc1ccc(OC(=O)Cc2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D08 compound treatment 0.333 0.00606 0.24 0.338 0.0114 0.24 0.3378 1.0 1138627 IFLab1_000426 CCOc1ccc2oc(c(N)c(=O)c2c1)c3cc(Br)cc4COCOc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D09 compound treatment 0.343 0.0161 0.63 0.337 0.0104 0.22 0.601 0.8994 1469300 IFLab1_000427 NC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D10 compound treatment 0.323 -0.00394 -0.15 0.335 0.00844 0.18 0.0154 0.0655 1217608 IFLab1_000428 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D11 compound treatment 0.342 0.0151 0.59 0.338 0.0114 0.24 0.588 0.9205 2066037 IFLab1_000429 NC1=C(C#N)C(C2CCCCC2)C3=C(CCCC3=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D12 compound treatment 0.341 0.0141 0.55 0.345 0.0184 0.39 0.6638 0.9845 1346635 IFLab1_000430 CCCc1cc2c(=O)c(coc2cc1O)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D13 compound treatment 0.33 0.00306 0.12 0.336 0.00944 0.2 0.2248 0.9718 2066038 IFLab1_000431 CC(C)(C)c1csc(NC(=O)c2ccc(F)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D14 compound treatment 0.352 0.0251 0.99 0.322 -0.00456 -0.1 0.6293 0.6356 2066039 IFLab1_000432 CCOC(=O)c1cc2cc(ccc2o1)c3c(C)oc4cc(O)ccc4c3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D15 compound treatment 0.323 -0.00394 -0.15 0.318 -0.00856 -0.18 -0.2362 -0.9973 2066040 IFLab1_000433 Cc1cc(O)cc2oc(c(c3cnn(c3)c4ccccc4)c(=O)c12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D16 compound treatment 0.359 0.0321 1.26 0.37 0.0434 0.91 1.5342 0.9871 1123607 IFLab1_000434 Clc1ccccc1Cc2cnc(NC(=O)c3ccco3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D17 compound treatment 0.341 0.0141 0.55 0.34 0.0134 0.28 0.5898 0.9508 1602403 IFLab1_000435 CC(=O)Oc1ccc2c(=O)c(coc2c1)c3nc4ccccc4n3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D18 compound treatment 0.422 0.0951 3.74 0.406 0.0794 1.66 3.8184 0.9334 2066041 IFLab1_000436 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCN(C)CC3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D19 compound treatment 0.34 0.0131 0.51 0.317 -0.00956 -0.2 0.2217 0.4022 1341629 IFLab1_000437 CCc1oc2cc(O)ccc2c(=O)c1c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D20 compound treatment 0.358 0.0311 1.22 0.361 0.0344 0.72 1.3732 0.9683 2066042 IFLab1_000438 CCOC(=O)CN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D21 compound treatment 0.347 0.0201 0.79 0.34 0.0134 0.28 0.7566 0.9035 1159801 IFLab1_000439 Oc1cc(O)c2c(=O)c(coc2c1)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D22 compound treatment 0.344 0.0171 0.67 0.348 0.0214 0.45 0.7916 0.9809 2066043 IFLab1_000440 C=CCOC(=O)CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D23 mock treatment 0.328 0.00106 0.04 0.321 -0.00556 -0.12 -0.0528 -0.4267 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 D24 positive control 0.079 -0.248 -9.75 0.08 -0.247 -5.16 -10.5416 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E01 compound treatment 0.329 0.00206 0.08 0.314 -0.0126 -0.26 -0.1285 -0.4673 2066044 IFLab1_000441 Cc1csc2nc(CSc3nc(C)cc(C)n3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E02 compound treatment 0.326 -9.37E-4 -0.04 0.319 -0.00756 -0.16 -0.138 -0.8491 1246562 IFLab1_000442 O=C(COc1ccc(Oc2ccccc2)cc1)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E03 compound treatment 0.337 0.0101 0.4 0.336 0.00944 0.2 0.4194 0.9485 2066045 IFLab1_000443 Cc1ccc(SCc2cn3c(C)cc(C)nc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E04 compound treatment 0.343 0.0161 0.63 0.344 0.0174 0.36 0.7046 0.966 2066046 IFLab1_000444 FC(F)(F)C(=C(C#N)C#N)N=C(c1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E05 compound treatment 0.322 -0.00494 -0.19 0.343 0.0164 0.34 0.106 0.2683 1184496 IFLab1_000445 Clc1cccc(c1)C(=O)NC2C3CC4CC(C3)CC2C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E06 compound treatment 0.351 0.0241 0.95 0.359 0.0324 0.68 1.149 0.9867 1560446 IFLab1_000446 C(c1cn2ccccc2n1)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E07 compound treatment 0.347 0.0201 0.79 0.366 0.0394 0.83 1.1413 0.9997 1582829 IFLab1_000447 Clc1ccc2oc(=O)c(cc2c1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E08 compound treatment 0.364 0.0371 1.46 0.363 0.0364 0.76 1.5696 0.9544 1165519 IFLab1_000448 CCC(=O)Nc1nc2cc3nc(NC(=O)CC)sc3cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E09 compound treatment 0.329 0.00206 0.08 0.352 0.0254 0.53 0.4337 0.8055 1479599 IFLab1_000449 Cc1ccc(C)c(c1)c2csc(=N)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E10 compound treatment 0.314 -0.0129 -0.51 0.353 0.0264 0.55 0.0315 0.0419 1301225 IFLab1_000450 Clc1ccc(cc1)C(=O)Nc2c(nc3ncccn23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E11 compound treatment 0.337 0.0101 0.4 0.342 0.0154 0.32 0.5082 0.9949 1516084 IFLab1_000451 CCCc1ccc(OCC(O)CN2CCN(C)CC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E12 compound treatment 0.224 -0.103 -4.05 0.254 -0.0726 -1.52 -3.9356 -0.9104 2066047 IFLab1_000452 O=C(NC(Sc1ccncn1)C(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E13 compound treatment 0.337 0.0101 0.4 0.34 0.0134 0.28 0.4786 0.986 2066048 IFLab1_000453 COC(=O)c1coc(n1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E14 compound treatment 0.352 0.0251 0.99 0.358 0.0314 0.66 1.162 0.9807 2066049 IFLab1_000454 Clc1ccc(s1)C(=O)Nc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E15 compound treatment 0.336 0.00906 0.36 0.344 0.0174 0.36 0.51 0.9999 1360834 IFLab1_000455 OC(=O)c1ccc(cc1)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E16 compound treatment 0.343 0.0161 0.63 0.343 0.0164 0.34 0.6898 0.9592 1103986 IFLab1_000456 Cc1cc(O)nc(SCC(=O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E17 compound treatment 0.36 0.0331 1.3 0.354 0.0274 0.57 1.3252 0.9325 1437896 IFLab1_000457 COc1cc(cc(OC)c1OC)c2onc3ccc(Cl)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E18 compound treatment 0.34 0.0131 0.51 0.337 0.0104 0.22 0.5176 0.9274 1591585 IFLab1_000458 Cc1cc(O)nc(SCC(=O)N2CCCC2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E19 compound treatment 0.341 0.0141 0.55 0.334 0.00744 0.16 0.501 0.8723 1297146 IFLab1_000459 CN(C)CCOC(=O)c1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E20 compound treatment 0.319 -0.00794 -0.31 0.316 -0.0106 -0.22 -0.377 -0.9857 1560447 IFLab1_000460 CCCSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2OC)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E21 compound treatment 0.331 0.00406 0.16 0.342 0.0154 0.32 0.3414 0.9473 2066050 IFLab1_000461 COc1ccc(NC(c2ccccc2)C(F)(F)CO)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E22 compound treatment 0.332 0.00506 0.2 0.341 0.0144 0.3 0.3544 0.9795 2066051 IFLab1_000462 CC(=O)Nc1nnc(s1)c2ccccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E23 mock treatment 0.329 0.00206 0.08 0.323 -0.00356 -0.07 0.0046 0.042 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 E24 positive control 0.081 -0.246 -9.67 0.081 -0.246 -5.14 -10.4712 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F01 compound treatment 0.372 0.0451 1.77 0.36 0.0334 0.7 1.7476 0.9174 1349364 IFLab1_000463 COc1cccc(c1)C(=O)Nc2nnc(s2)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F02 compound treatment 0.318 -0.00894 -0.35 0.317 -0.00956 -0.2 -0.39 -0.9644 3176014 IFLab1_000464 CC[n+]1c(C)scc1c2c(C)oc3cc(O)ccc3c2=O.Cc1ccc(cc1)S(=O)(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F03 compound treatment 0.32 -0.00694 -0.27 0.322 -0.00456 -0.1 -0.2604 -0.901 2066053 IFLab1_000465 C/C=C/c1n(C)c2ccccc2[n+]1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F04 compound treatment 0.322 -0.00494 -0.19 0.336 0.00944 0.2 0.0024 0.0086 1255057 IFLab1_000466 O=C1CC(Oc2ccccc12)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F05 compound treatment 0.313 -0.0139 -0.55 0.344 0.0174 0.36 -0.1295 -0.1966 1043657 IFLab1_000467 Clc1ccccc1NS(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F06 compound treatment 0.331 0.00406 0.16 0.373 0.0464 0.97 0.8001 0.8124 2066054 IFLab1_000468 O=c1c(coc2ccccc12)c3cc4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F07 compound treatment 0.32 -0.00694 -0.27 0.318 -0.00856 -0.18 -0.3196 -0.9792 1587529 IFLab1_000469 Fc1ccc(cc1)C(=O)Nc2cccc(OC(=O)c3ccc(F)cc3)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F08 compound treatment 0.331 0.00406 0.16 0.344 0.0174 0.36 0.371 0.9313 1289161 IFLab1_000470 Cc1nc(cs1)c2c[nH]nc2c3ccc(O)c(C)c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F09 compound treatment 0.33 0.00306 0.12 0.331 0.00444 0.09 0.1508 0.9918 1137982 IFLab1_000471 CCCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F10 compound treatment 0.298 -0.0289 -1.14 0.303 -0.0236 -0.49 -1.1532 -0.93 1540974 IFLab1_000472 CCc1cc(c2n[nH]cc2c3ccc(Br)cc3)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F11 compound treatment 0.347 0.0201 0.79 0.347 0.0204 0.43 0.8602 0.9586 1724075 IFLab1_000473 COc1ccc(cc1OC)c2csc(NC(=O)Cc3ccccc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F12 compound treatment 0.337 0.0101 0.4 0.355 0.0284 0.6 0.7006 0.9803 1126855 IFLab1_000474 CCCc1cc2c(=O)c(coc2cc1OC(=O)C)c3nc(C)cs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F13 compound treatment 0.281 -0.0459 -1.81 0.342 0.0154 0.32 -1.0487 -0.5716 1606685 IFLab1_000475 COc1ccc(cc1)C(=O)Nc2nc(cs2)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F14 compound treatment 0.339 0.0121 0.47 0.346 0.0194 0.41 0.623 0.9971 1695634 IFLab1_000476 CCOC(=O)c1ccc(o1)c2coc3cc(OC)c(CC)cc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F15 compound treatment 0.335 0.00806 0.32 0.344 0.0174 0.36 0.4822 0.9975 1568951 IFLab1_000477 COc1ccc2c(=O)c(coc2c1)c3cnn(c3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F16 compound treatment 0.337 0.0101 0.4 0.338 0.0114 0.24 0.449 0.971 2066055 IFLab1_000478 COc1ccc(CC2SC(=N)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F17 compound treatment 0.336 0.00906 0.36 0.34 0.0134 0.28 0.4508 0.9931 1296030 IFLab1_000479 COc1ccc(c2onc(C)c2c3cscn3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F18 compound treatment 0.36 0.0331 1.3 0.353 0.0264 0.55 1.3104 0.9275 2066056 IFLab1_000480 CN1CCN(CC1)C(=O)CCCN2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F19 compound treatment 0.338 0.0111 0.43 0.35 0.0234 0.49 0.6544 0.9982 1349453 IFLab1_000481 CCc1cc2c(=O)c(coc2cc1O)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F20 compound treatment 0.36 0.0331 1.3 0.351 0.0244 0.51 1.2808 0.9169 1922550 IFLab1_000482 CCCOC(=O)CN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F21 compound treatment 0.333 0.00606 0.24 0.335 0.00844 0.18 0.2934 0.9891 2066057 IFLab1_000483 COc1ccc2c(=O)c(c3cscn3)c(oc2c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F22 compound treatment 0.345 0.0181 0.71 0.336 0.00944 0.2 0.6418 0.8707 2066058 IFLab1_000484 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F23 mock treatment 0.32 -0.00694 -0.27 0.327 4.38E-4 0.01 -0.1864 -0.683 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 F24 positive control 0.082 -0.245 -9.63 0.081 -0.246 -5.14 -10.4434 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G01 compound treatment 0.339 0.0121 0.47 0.34 0.0134 0.28 0.5342 0.9689 2066059 IFLab1_000485 Cc1cc(C)nc(SCc2cn3ccccc3n2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G02 compound treatment 0.446 0.119 4.68 0.442 0.115 2.42 5.0183 0.9526 1415634 IFLab1_000486 CCN(CC)c1ccc2cc(C(=O)N)c(=N)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G03 compound treatment 0.347 0.0201 0.79 0.341 0.0144 0.3 0.7714 0.9132 2066060 IFLab1_000487 Cc1csc2nc(CSc3ccc(C)cc3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G04 compound treatment 0.336 0.00906 0.36 0.327 4.38E-4 0.01 0.2584 0.725 1136925 IFLab1_000488 CCOC(=O)Cc1csc(NC(=O)c2ccc(Br)cc2F)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G05 compound treatment 0.331 0.00406 0.16 0.318 -0.00856 -0.18 -0.0138 -0.0573 2066061 IFLab1_000489 Oc1ccc(cc1)C(CCl)n2cncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G06 compound treatment 0.297 -0.0299 -1.18 0.31 -0.0166 -0.35 -1.0774 -0.878 1320990 IFLab1_000490 CCOC(=O)c1coc2c(F)c(F)c(F)cc2c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G07 compound treatment 0.324 -0.00294 -0.12 0.348 0.0214 0.45 0.2355 0.5085 1445944 IFLab1_000491 CCOC(=O)c1cc2cc(Br)ccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G08 compound treatment 0.373 0.0461 1.81 0.362 0.0354 0.74 1.805 0.9223 1536983 IFLab1_000492 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G09 compound treatment 0.345 0.0181 0.71 0.334 0.00744 0.16 0.6122 0.8421 1252330 IFLab1_000493 Cc1cc(C)c(c2csc(=N)[nH]2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G10 compound treatment 0.335 0.00806 0.32 0.339 0.0124 0.26 0.4082 0.9952 1284273 IFLab1_000494 COC(=O)Nc1c(nc2ccccn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G11 compound treatment 0.32 -0.00694 -0.27 0.316 -0.0106 -0.22 -0.3492 -0.9946 1474573 IFLab1_000495 CCCc1ccc(OCC(O)CNC(C)(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G12 compound treatment 0.325 -0.00194 -0.08 0.335 0.00844 0.18 0.071 0.3691 2066062 IFLab1_000496 Clc1ccc(s1)c2csc(NC(=O)c3ccco3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G13 compound treatment 0.329 0.00206 0.08 0.34 0.0134 0.28 0.2562 0.8754 1473618 IFLab1_000497 CN(C)c1oc(nc1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G14 compound treatment 0.351 0.0241 0.95 0.319 -0.00756 -0.16 0.5571 0.5808 2066063 IFLab1_000498 CCOC(=O)c1ccc(NC(=O)c2ccc(Cl)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G15 compound treatment 0.325 -0.00194 -0.08 0.334 0.00744 0.16 0.0562 0.3243 2066064 IFLab1_000499 COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G16 compound treatment 0.307 -0.0199 -0.78 0.327 4.38E-4 0.01 -0.5478 -0.6988 2066065 IFLab1_000500 NC(=O)CSc1ncnc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G17 compound treatment 0.337 0.0101 0.4 0.343 0.0164 0.34 0.523 0.9976 2066066 IFLab1_000501 Cc1nn(c2ccccc2)c3sc(C#N)c(N)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G18 compound treatment 0.337 0.0101 0.4 0.337 0.0104 0.22 0.4342 0.9608 1503906 IFLab1_000502 Cc1cc(nc(SCC(=O)N2CCCC2)n1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G19 compound treatment 0.334 0.00706 0.28 0.332 0.00544 0.11 0.2768 0.9224 2066067 IFLab1_000503 O/C(=C(/C#N)\c1nc2ccccc2s1)/C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G20 compound treatment 0.337 0.0101 0.4 0.351 0.0244 0.51 0.6414 0.992 1378607 IFLab1_000504 CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G21 compound treatment 0.335 0.00806 0.32 0.333 0.00644 0.13 0.3194 0.9273 2066068 IFLab1_000505 NC(c1ccccc1)C(F)(F)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G22 compound treatment 0.329 0.00206 0.08 0.33 0.00344 0.07 0.1082 0.9982 1248621 IFLab1_000506 CCCCC(=O)Nc1nnc(s1)c2ccc(OC)cc2OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G23 mock treatment 0.321 -0.00594 -0.23 0.318 -0.00856 -0.18 -0.2918 -0.9915 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 G24 positive control 0.081 -0.246 -9.67 0.081 -0.246 -5.14 -10.4712 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H01 compound treatment 0.377 0.0501 1.97 0.363 0.0364 0.76 1.931 0.9148 1478424 IFLab1_000507 COc1ccc(c2nnc(NC(=O)c3cc(C)cc(C)c3)s2)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H02 compound treatment 0.339 0.0121 0.47 0.321 -0.00556 -0.12 0.2531 0.5182 1565369 IFLab1_000508 COc1cc(C)c2c(=O)c(coc2c1)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H03 compound treatment 0.388 0.0611 2.4 0.378 0.0514 1.08 2.4588 0.9345 2066069 IFLab1_000509 NS(=O)(=O)c1ccc(/N=C/2\C(=O)Nc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H04 compound treatment 0.347 0.0201 0.79 0.34 0.0134 0.28 0.7566 0.9035 1213399 IFLab1_000510 CCCc1cc2c(=O)c(coc2cc1OC)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H05 compound treatment 0.327 6.25E-5 0.0 0.333 0.00644 0.13 0.097 0.7199 2066070 IFLab1_000511 Cc1ccccc1S(=O)(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H06 compound treatment 0.327 6.25E-5 0.0 0.349 0.0224 0.47 0.3337 0.7108 1422397 IFLab1_000512 CCc1cc2c(=O)c(coc2cc1OC(=O)C)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H07 compound treatment 0.341 0.0141 0.55 0.332 0.00544 0.11 0.4714 0.8351 1335854 IFLab1_000513 Clc1cccc(c1)C(=O)Oc2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H08 compound treatment 0.328 0.00106 0.04 0.337 0.0104 0.22 0.184 0.8274 2066071 IFLab1_000514 ON=c1cc(oc2ccccc12)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H09 compound treatment 0.354 0.0271 1.06 0.379 0.0524 1.1 1.5283 0.9999 1578674 IFLab1_000515 O=c1oc2ccccc2cc1c3nc(cs3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H10 compound treatment 0.35 0.0231 0.91 0.34 0.0134 0.28 0.84 0.8848 1420322 IFLab1_000516 CC(=O)Oc1ccc2c(=O)c(coc2c1)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H11 compound treatment 0.339 0.0121 0.47 0.319 -0.00756 -0.16 0.2235 0.4469 2066072 IFLab1_000517 Cc1ccc(cc1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H12 compound treatment 0.342 0.0151 0.59 0.352 0.0254 0.53 0.7952 0.9986 2066073 IFLab1_000518 Cc1oc2cc(O)ccc2c(=O)c1c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H13 compound treatment 0.352 0.0251 0.99 0.365 0.0384 0.8 1.2656 0.9949 1211272 IFLab1_000519 CC(C)(C)c1csc(NC(=O)c2ccc(C#N)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H14 compound treatment 0.348 0.0211 0.83 0.341 0.0144 0.3 0.7992 0.9066 1661025 IFLab1_000520 CCOC(=O)c1ccc(o1)c2coc3cc(O)c(CC)cc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H15 compound treatment 0.344 0.0171 0.67 0.327 4.38E-4 0.01 0.4808 0.7167 1247029 IFLab1_000521 COc1ccc(C(=O)Cc2cnn(c2)c3ccccc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H16 compound treatment 0.335 0.00806 0.32 0.339 0.0124 0.26 0.4082 0.9952 2066074 IFLab1_000522 Clc1ccccc1CC2S/C(=N/c3ccccc3)/NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H17 compound treatment 0.342 0.0151 0.59 0.349 0.0224 0.47 0.7508 0.9934 1317931 IFLab1_000523 CCc1cc2c(=O)c(coc2cc1O)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H18 compound treatment 0.536 0.209 8.22 0.533 0.206 4.32 8.867 0.9549 2066075 IFLab1_000524 OC(=O)CCCN1C(=O)/C(=C\2/C(=O)Nc3ccccc23)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H19 compound treatment 0.337 0.0101 0.4 0.343 0.0164 0.34 0.523 0.9976 2066076 IFLab1_000525 Fc1ccc2oc(cc(=O)c2c1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H20 compound treatment 0.351 0.0241 0.95 0.353 0.0264 0.55 1.0602 0.9673 1922508 IFLab1_000526 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)OC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H21 compound treatment 0.32 -0.00694 -0.27 0.34 0.0134 0.28 0.006 0.0152 1486099 IFLab1_000527 Oc1ccc2c(=O)c(coc2c1)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H22 compound treatment 0.398 0.0711 2.79 0.402 0.0754 1.58 3.0919 0.9635 2066077 IFLab1_000528 COc1ccc(/C=C/2\SC(=S)N(C2=O)c3ccc(O)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H23 mock treatment 0.333 0.00606 0.24 0.322 -0.00456 -0.1 0.101 0.3935 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 H24 positive control 0.083 -0.244 -9.59 0.083 -0.244 -5.1 -10.386 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I01 compound treatment 0.312 -0.0149 -0.59 0.346 0.0194 0.41 -0.1277 -0.1787 1615739 IFLab1_000529 Cc1ccc(SCc2cn3ccccc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I02 compound treatment 0.358 0.0311 1.22 0.374 0.0474 0.99 1.5655 0.9947 2066078 IFLab1_000530 Oc1ccc2ccccc2c1/C=N/c3ncccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I03 compound treatment 0.34 0.0131 0.51 0.338 0.0114 0.24 0.5324 0.9396 2066079 IFLab1_000531 Cc1ccc(SCc2cn3ccsc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I04 compound treatment 0.352 0.0251 0.99 0.368 0.0414 0.87 1.3099 0.998 1491476 IFLab1_000532 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(Br)cc3F)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I05 compound treatment 0.362 0.0351 1.38 0.356 0.0294 0.62 1.4104 0.9341 2066080 IFLab1_000533 NCc1cn2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I06 compound treatment 0.356 0.0291 1.14 0.349 0.0224 0.47 1.14 0.9228 1263079 IFLab1_000534 COc1ccc(cc1)c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I07 compound treatment 0.399 0.0721 2.83 0.385 0.0584 1.22 2.8682 0.9294 1577290 IFLab1_000535 COc1cccc2cc(c3csc(N)n3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I08 compound treatment 0.351 0.0241 0.95 0.339 0.0124 0.26 0.853 0.8693 1694764 IFLab1_000536 Clc1ccc(OCc2cn3ccccc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I09 compound treatment 0.35 0.0231 0.91 0.356 0.0294 0.62 1.0768 0.9823 2066081 IFLab1_000537 Fc1cccc(Cl)c1C=c2sc3nc4ccccc4n3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I10 compound treatment 0.349 0.0221 0.87 0.35 0.0234 0.49 0.9602 0.9636 1378406 IFLab1_000538 Cc1ccc(cc1)C(=O)Nc2c(nc3scnn23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I11 compound treatment 0.335 0.00806 0.32 0.341 0.0144 0.3 0.4378 0.9997 1527411 IFLab1_000539 CC(C)c1ccc(OCC(O)CN2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I12 compound treatment 0.34 0.0131 0.51 0.379 0.0524 1.1 1.1391 0.9402 1602410 IFLab1_000540 COc1ccc(cc1OC)C(=O)N=c2sc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I13 compound treatment 0.33 0.00306 0.12 0.345 0.0184 0.39 0.358 0.8857 2066082 IFLab1_000541 CC(C)C(=O)Nc1nc(cs1)c2ccc(C)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I14 compound treatment 0.345 0.0181 0.71 0.342 0.0154 0.32 0.7306 0.9364 1345171 IFLab1_000542 NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I15 compound treatment 0.332 0.00506 0.2 0.34 0.0134 0.28 0.3396 0.9857 2066083 IFLab1_000543 C(/N=C/c1ccc2OCOc2c1)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I16 compound treatment 0.337 0.0101 0.4 0.339 0.0124 0.26 0.4638 0.9794 1492342 IFLab1_000544 Cc1nc2ccccc2nc1SCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I17 compound treatment 0.341 0.0141 0.55 0.354 0.0274 0.57 0.797 0.9998 1660276 IFLab1_000545 Oc1c(C(=O)NCc2ccccc2)c(=O)[nH]c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I18 compound treatment 0.344 0.0171 0.67 0.334 0.00744 0.16 0.5844 0.8486 2066084 IFLab1_000546 Clc1nc2ccccc2nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I19 compound treatment 0.335 0.00806 0.32 0.318 -0.00856 -0.18 0.0975 0.2676 2066085 IFLab1_000547 COc1ccccc1N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I20 compound treatment 0.344 0.0171 0.67 0.347 0.0204 0.43 0.7768 0.9764 2066086 IFLab1_000548 CC1(C)C(C#N)C(=O)NC(=C1C#N)SCC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I21 compound treatment 0.332 0.00506 0.2 0.347 0.0204 0.43 0.4432 0.9394 1483937 IFLab1_000549 CC(C)NC(=O)COc1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I22 compound treatment 0.336 0.00906 0.36 0.322 -0.00456 -0.1 0.1844 0.5 2066087 IFLab1_000550 CCCCC(=O)Nc1nnc(s1)c2c(C)c(C)cc(C)c2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I23 mock treatment 0.333 0.00606 0.24 0.33 0.00344 0.07 0.2194 0.8812 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 I24 positive control 0.083 -0.244 -9.59 0.084 -0.243 -5.08 -10.3712 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J01 compound treatment 0.327 6.25E-5 0.0 0.35 0.0234 0.49 0.3485 0.7106 1207239 IFLab1_000551 Cc1cc(C)c(c2nnc(NC(=O)c3cccs3)s2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J02 compound treatment 0.332 0.00506 0.2 0.334 0.00744 0.16 0.2508 0.9926 1206421 IFLab1_000552 Cc1cc(O)c2c(=O)c(c3cscn3)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J03 compound treatment 0.359 0.0321 1.26 0.352 0.0254 0.53 1.2678 0.9265 2066088 IFLab1_000553 Oc1c(CC=C)cccc1/C=N/C2=C(CCC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J04 compound treatment 0.325 -0.00194 -0.08 0.331 0.00444 0.09 0.0118 0.0982 1691238 IFLab1_000554 CCCCc1cc2c(=O)c(coc2cc1O)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J05 compound treatment 0.346 0.0191 0.75 0.332 0.00544 0.11 0.6104 0.8052 1088882 IFLab1_000555 Cc1cc(C)c(c(C)c1)S(=O)(=O)n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J06 compound treatment 0.326 -9.37E-4 -0.04 0.337 0.0104 0.22 0.1284 0.5796 1214890 IFLab1_000556 CCc1cc2c(=O)c(coc2cc1OC)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J07 compound treatment 0.334 0.00706 0.28 0.338 0.0114 0.24 0.3656 0.9973 2066089 IFLab1_000557 COc1ccc(cc1)C(=O)CSc2nc(C)cc(C)c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J08 compound treatment 0.371 0.0441 1.73 0.355 0.0284 0.6 1.6458 0.8985 1143247 IFLab1_000558 Cc1ccc(O)c(c1)c2cc([nH]n2)c3ncc(Cl)n3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J09 compound treatment 0.332 0.00506 0.2 0.351 0.0244 0.51 0.5024 0.9154 1200252 IFLab1_000559 CCCSC1=C(C#N)C(CC(=O)N1)c2cc(OC)ccc2OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J10 compound treatment 0.354 0.0271 1.06 0.352 0.0254 0.53 1.1288 0.9488 1449786 IFLab1_000560 Oc1ccc(C(=O)Cc2ccc3OCCCOc3c2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J11 compound treatment 0.309 -0.0179 -0.71 0.349 0.0224 0.47 -0.1667 -0.1967 2066090 IFLab1_000561 Brc1cccc(c1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J12 compound treatment 0.335 0.00806 0.32 0.32 -0.00656 -0.14 0.127 0.3678 1427754 IFLab1_000562 CCCc1cc2c(=O)c(coc2cc1O)c3ccc(o3)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J13 compound treatment 0.347 0.0201 0.79 0.327 4.38E-4 0.01 0.5643 0.7153 2066091 IFLab1_000563 COC(=O)Nc1ccc(SCC(=O)c2ccc(Cl)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J14 compound treatment 0.36 0.0331 1.3 0.346 0.0194 0.41 1.2068 0.886 2066092 IFLab1_000564 Clc1ccc(cc1)c2nc(C#N)c(NCc3ccco3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J15 compound treatment 0.332 0.00506 0.2 0.336 0.00944 0.2 0.2804 1.0 1566339 IFLab1_000565 COc1ccc2c(=O)c(coc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J16 compound treatment 0.341 0.0141 0.55 0.342 0.0154 0.32 0.6194 0.9673 2066093 IFLab1_000566 Clc1ccc(/N=C/2\NC(=O)CS2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J17 compound treatment 0.345 0.0181 0.71 0.348 0.0214 0.45 0.8194 0.9755 1195576 IFLab1_000567 Cn1c(Cl)cnc1C2CC(=O)c3cc(Cl)ccc3O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J18 compound treatment 0.37 0.0431 1.69 0.369 0.0424 0.89 1.8252 0.9546 1921718 IFLab1_000568 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccc(cc3)C(=O)O)/c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J19 compound treatment 0.382 0.0551 2.16 0.38 0.0534 1.12 2.3216 0.9528 1611959 IFLab1_000569 COc1ccc2c(=S)c(c3csc(C)n3)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J20 compound treatment 0.359 0.0321 1.26 0.361 0.0344 0.72 1.401 0.9648 1922520 IFLab1_000570 COC(=O)CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J21 compound treatment 0.352 0.0251 0.99 0.345 0.0184 0.39 0.9696 0.9162 2066094 IFLab1_000571 O/N=C(\Cc1cscn1)/c2ccc(O)cc2O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J22 compound treatment 0.35 0.0231 0.91 0.346 0.0194 0.41 0.9288 0.9346 2066095 IFLab1_000572 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccc(O)cc3)/c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J23 mock treatment 0.334 0.00706 0.28 0.326 -5.62E-4 -0.01 0.188 0.6765 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 J24 positive control 0.084 -0.243 -9.55 0.085 -0.242 -5.06 -10.3286 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K01 compound treatment 0.364 0.0371 1.46 0.359 0.0324 0.68 1.5104 0.9396 1409705 IFLab1_000573 C(Sc1nc2ccccc2[nH]1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K02 compound treatment 0.329 0.00206 0.08 0.347 0.0204 0.43 0.3598 0.8265 2066096 IFLab1_000574 CCOc1nc(nc(Cl)c1N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K03 compound treatment 0.329 0.00206 0.08 0.328 0.00144 0.03 0.0786 0.9089 2066097 IFLab1_000575 Cc1cc(C)nc(SCc2nc3sccn3c2Br)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K04 compound treatment 0.338 0.0111 0.43 0.334 0.00744 0.16 0.4176 0.904 1265730 IFLab1_000576 CCOc1cccc(NC(=O)c2ccc(Br)cc2F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K05 compound treatment 0.325 -0.00194 -0.08 0.327 4.38E-4 0.01 -0.0474 -0.6177 1210575 IFLab1_000577 Cc1ccc(NC(=O)CC#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K06 compound treatment 0.33 0.00306 0.12 0.346 0.0194 0.41 0.3728 0.8787 1382919 IFLab1_000578 CCOc1ccc(NCc2cn3cccnc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K07 compound treatment 0.346 0.0191 0.75 0.362 0.0354 0.74 1.0543 1.0 1734743 IFLab1_000579 CC(=O)NC(=O)c1cc2ccccc2oc1=Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K08 compound treatment 0.341 0.0141 0.55 0.357 0.0304 0.64 0.8414 0.9975 1536710 IFLab1_000580 Nc1ccccc1SCc2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K09 compound treatment 0.344 0.0171 0.67 0.343 0.0164 0.34 0.7176 0.9518 1018829 IFLab1_000581 O=C(NS(=O)(=O)c1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K10 compound treatment 0.354 0.0271 1.06 0.337 0.0104 0.22 0.9068 0.8348 2066098 IFLab1_000582 CC(=O)NCS(=O)(=O)c1ccc(C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K11 compound treatment 0.347 0.0201 0.79 0.349 0.0224 0.47 0.8898 0.9693 1450771 IFLab1_000583 CCc1ccc(OCC(O)CN2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K12 compound treatment 0.348 0.0211 0.83 0.366 0.0394 0.83 1.1691 1.0 2066099 IFLab1_000584 Cn1c(=NC(=O)/C=C\c2ccccc2)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K13 compound treatment 0.325 -0.00194 -0.08 0.339 0.0124 0.26 0.1302 0.48 1025093 IFLab1_000585 OC(=O)CC1Sc2ccccc2NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K14 compound treatment 0.349 0.0221 0.87 0.35 0.0234 0.49 0.9602 0.9636 2066100 IFLab1_000586 Clc1ccc(s1)C(=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K15 compound treatment 0.348 0.0211 0.83 0.348 0.0214 0.45 0.9028 0.9585 1520940 IFLab1_000587 OC(=O)c1ccc(cc1)S(=O)(=O)n2ncc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K16 compound treatment 0.347 0.0201 0.79 0.348 0.0214 0.45 0.875 0.9642 1739560 IFLab1_000588 Cc1nc2ccccc2nc1SC(C(=O)O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K17 compound treatment 0.368 0.0411 1.61 0.357 0.0304 0.64 1.592 0.9173 1155994 IFLab1_000589 Cc1cccc(c1)C(=O)Nc2nc(cs2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K18 compound treatment 0.343 0.0161 0.63 0.345 0.0184 0.39 0.7194 0.9721 2066101 IFLab1_000590 Cc1nnc2c(nc3ccccc3n12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K19 compound treatment 0.346 0.0191 0.75 0.344 0.0174 0.36 0.788 0.9453 1634249 IFLab1_000591 OC(=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K20 compound treatment 0.345 0.0181 0.71 0.361 0.0344 0.72 1.0117 1.0 2066102 IFLab1_000592 Nc1nc(SCc2ccccc2)c(C#N)c(c1C#N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K21 compound treatment 0.344 0.0171 0.67 0.337 0.0104 0.22 0.6288 0.8913 1576638 IFLab1_000593 Brc1ccc(OCC(=O)NCc2ccco2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K22 compound treatment 0.349 0.0221 0.87 0.341 0.0144 0.3 0.827 0.9003 1737940 IFLab1_000594 CC(C)(C)C(=O)Nc1nnc(s1)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K23 mock treatment 0.333 0.00606 0.24 0.323 -0.00356 -0.07 0.1158 0.4638 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 K24 positive control 0.087 -0.24 -9.43 0.086 -0.241 -5.03 -10.2304 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L01 compound treatment 0.354 0.0271 1.06 0.345 0.0184 0.39 1.0252 0.9058 1688908 IFLab1_000595 CCOc1ccc(cc1)C(=O)Nc2nnc(s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L02 compound treatment 0.347 0.0201 0.79 0.356 0.0294 0.62 0.9934 0.9925 2066103 IFLab1_000596 Brc1ccc2oc(=O)c(cc2c1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L03 compound treatment 0.352 0.0251 0.99 0.357 0.0304 0.64 1.1472 0.9777 2066104 IFLab1_000597 Oc1ccc2ccccc2c1/C=N/C3=C(CCC3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L04 compound treatment 0.332 0.00506 0.2 0.345 0.0184 0.39 0.4136 0.9526 1626953 IFLab1_000598 Cc1nc(cs1)c2coc3cc(O)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L05 compound treatment 0.338 0.0111 0.43 0.35 0.0234 0.49 0.6544 0.9982 2066105 IFLab1_000599 O=S(=O)(/C=C/c1ccccc1)n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L06 compound treatment 0.335 0.00806 0.32 0.332 0.00544 0.11 0.3046 0.9044 1711938 IFLab1_000600 COC(=O)COc1cc2occ(c3csc(C)n3)c(=O)c2cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L07 compound treatment 0.387 0.0601 2.36 0.375 0.0484 1.01 2.3866 0.9287 1481629 IFLab1_000601 CC(C)C1C(=C(N)Oc2c1c(=O)oc3ccccc23)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L08 compound treatment 0.349 0.0221 0.87 0.351 0.0244 0.51 0.975 0.9682 1513242 IFLab1_000602 COc1ccc(c(O)c1OC)c2ncncc2c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L09 compound treatment 0.348 0.0211 0.83 0.37 0.0434 0.91 1.2283 0.9989 2066106 IFLab1_000603 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L10 compound treatment 0.324 -0.00294 -0.12 0.325 -0.00156 -0.03 -0.1048 -0.873 1240381 IFLab1_000604 CCCc1cc(C(=O)Cc2ccc3OCOc3c2)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L11 compound treatment 0.357 0.0301 1.18 0.359 0.0324 0.68 1.3158 0.9653 2066107 IFLab1_000605 COc1cc(OC)cc(c1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L12 compound treatment 0.354 0.0271 1.06 0.363 0.0364 0.76 1.2916 0.9866 1235291 IFLab1_000606 CCc1cc2c(=O)c(coc2cc1OC)c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L13 compound treatment 0.345 0.0181 0.71 0.346 0.0194 0.41 0.7898 0.965 2066108 IFLab1_000607 Cc1nnc2n(c3ccccc3)c(=O)c4ccccc4n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L14 compound treatment 0.322 -0.00494 -0.19 0.348 0.0214 0.45 0.1799 0.3681 2066109 IFLab1_000608 NNc1oc(nc1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L15 compound treatment 0.345 0.0181 0.71 0.346 0.0194 0.41 0.7898 0.965 1466966 IFLab1_000609 Oc1ccc2c(=O)c(Oc3ccccc3)coc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L16 compound treatment 0.364 0.0371 1.46 0.362 0.0354 0.74 1.5548 0.9509 2066110 IFLab1_000610 Cc1sc2nc(SCC=C)[nH]c(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L17 compound treatment 0.332 0.00506 0.2 0.35 0.0234 0.49 0.4876 0.9211 1123889 IFLab1_000611 Cc1oc2cc(O)cc(O)c2c(=O)c1c3ccc4OCCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L18 compound treatment 0.335 0.00806 0.32 0.349 0.0224 0.47 0.5562 0.9817 2066111 IFLab1_000612 OC(=O)CN1C(=O)S/C(=C\c2ccc(Br)cc2)/C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L19 compound treatment 0.339 0.0121 0.47 0.341 0.0144 0.3 0.549 0.9763 1262600 IFLab1_000613 CCc1cc(C(=O)Cc2c[nH]cn2)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L20 compound treatment 0.351 0.0241 0.95 0.355 0.0284 0.6 1.0898 0.975 1922147 IFLab1_000614 O=C(CCN1C(=O)/C(=C/c2ccccc2)/SC1=S)OC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L21 compound treatment 0.341 0.0141 0.55 0.34 0.0134 0.28 0.5898 0.9508 1139636 IFLab1_000615 COC(=O)c1cc(CC#N)c(C)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L22 compound treatment 0.404 0.0771 3.03 0.41 0.0834 1.75 3.3771 0.9657 1717907 IFLab1_000616 Oc1cccc(c1)N2C(=O)CSC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L23 mock treatment 0.326 -9.37E-4 -0.04 0.336 0.00944 0.2 0.1136 0.5654 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 L24 positive control 0.086 -0.241 -9.47 0.088 -0.239 -4.99 -10.2286 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M01 compound treatment 0.357 0.0301 1.18 0.332 0.00544 0.11 0.9163 0.7716 2066112 IFLab1_000617 Clc1ccc(SCc2nc3ncccn3c2Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M02 compound treatment 0.34 0.0131 0.51 0.345 0.0184 0.39 0.636 0.9901 2066113 IFLab1_000618 Oc1ccc(Br)cc1/C=N/S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M03 compound treatment 0.331 0.00406 0.16 0.342 0.0154 0.32 0.3414 0.9473 1697044 IFLab1_000619 CC(C)C(=O)Nc1sc2CCCc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M04 compound treatment 0.321 -0.00594 -0.23 0.314 -0.0126 -0.26 -0.351 -0.9982 1176687 IFLab1_000620 CCOc1ccccc1NC(=O)c2ccc(Br)cc2F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M05 compound treatment 0.317 -0.00994 -0.39 0.324 -0.00256 -0.05 -0.3142 -0.7967 2066114 IFLab1_000621 COC(=O)c1cc2ccccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M06 compound treatment 0.351 0.0241 0.95 0.348 0.0214 0.45 0.9862 0.9419 1630490 IFLab1_000622 Cc1cccn2cc(CN3CCCc4ccccc34)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M07 compound treatment 0.409 0.0821 3.23 0.397 0.0704 1.47 3.3238 0.937 1651667 IFLab1_000623 Fc1ccc(Nc2nc(cs2)c3cc4ccccc4oc3=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M08 compound treatment 0.329 0.00206 0.08 0.342 0.0154 0.32 0.2858 0.858 1199946 IFLab1_000624 Clc1ccc(OC(=O)c2ccncc2)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M09 compound treatment 0.335 0.00806 0.32 0.345 0.0184 0.39 0.497 0.9952 1917560 IFLab1_000625 O=C(CSc1nnc[nH]1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M10 compound treatment 0.336 0.00906 0.36 0.334 0.00744 0.16 0.362 0.931 2066115 IFLab1_000626 CC(=O)Nc1nc(c2ccccc2)[n+](s1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M11 compound treatment 0.33 0.00306 0.12 0.341 0.0144 0.3 0.2988 0.9187 1254501 IFLab1_000627 CCc1ccc(OCC(O)CNC(C)(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M12 compound treatment 0.341 0.0141 0.55 0.358 0.0314 0.66 0.8561 0.9963 1676295 IFLab1_000628 Cc1ccc(cc1)C(=O)Nc2nc3CC(C)(C)CC(=O)c3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M13 compound treatment 0.359 0.0321 1.26 0.345 0.0184 0.39 1.1642 0.8831 1713221 IFLab1_000629 CCOc1ccc(cc1)c2cc3ccccn3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M14 compound treatment 0.337 0.0101 0.4 0.352 0.0254 0.53 0.6562 0.9893 1697812 IFLab1_000630 OC(=O)CSc1nc2ccccc2nc1SCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M15 compound treatment 0.333 0.00606 0.24 0.327 4.38E-4 0.01 0.175 0.7337 2066116 IFLab1_000631 C1Oc2ccc(/C=N/c3ccc(cc3)N4CCOCC4)cc2O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M16 compound treatment 0.343 0.0161 0.63 0.345 0.0184 0.39 0.7194 0.9721 1251723 IFLab1_000632 Cc1ccnc(SC(C(=O)O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M17 compound treatment 0.337 0.0101 0.4 0.328 0.00144 0.03 0.301 0.7587 1718133 IFLab1_000633 COc1ccc(NC(=O)C2CCCCC2C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M18 compound treatment 0.349 0.0221 0.87 0.349 0.0224 0.47 0.9454 0.9585 1608218 IFLab1_000634 Cc1ccccc1n2c(=O)c3ccccc3n4nnnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M19 compound treatment 0.367 0.0401 1.58 0.365 0.0384 0.8 1.6826 0.9513 2066117 IFLab1_000635 CC1CCc2sc(NC(=O)c3ccco3)c(C#N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M20 compound treatment 0.329 0.00206 0.08 0.35 0.0234 0.49 0.4041 0.813 2066118 IFLab1_000636 Clc1cccc(Cl)c1NC2=NCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M21 compound treatment 0.346 0.0191 0.75 0.336 0.00944 0.2 0.6696 0.8639 1316539 IFLab1_000637 CN(Cc1ccccc1)C(=O)COc2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M22 compound treatment 0.353 0.0261 1.02 0.348 0.0214 0.45 1.0418 0.9313 1716728 IFLab1_000638 Cc1ccc(cc1)C(=O)Nc2nnc(s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M23 mock treatment 0.3 -0.0269 -1.06 0.333 0.00644 0.13 -0.6537 -0.6122 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 M24 positive control 0.087 -0.24 -9.43 0.089 -0.238 -4.97 -10.186 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N01 compound treatment 0.336 0.00906 0.36 0.342 0.0154 0.32 0.4804 0.9988 1183943 IFLab1_000639 Brc1ccc(cc1)c2nnc(NC(=O)Cc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N02 compound treatment 0.342 0.0151 0.59 0.352 0.0254 0.53 0.7952 0.9986 1722057 IFLab1_000640 Oc1ccc2c(=O)c(coc2c1)c3cc4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N03 compound treatment 0.378 0.0511 2.01 0.381 0.0544 1.14 2.2252 0.964 1514271 IFLab1_000641 COc1cccc(NC2SC(=O)N(C2=O)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N04 compound treatment 0.345 0.0181 0.71 0.347 0.0204 0.43 0.8046 0.9705 1470825 IFLab1_000642 OC(=O)COc1ccc2c(=O)c(coc2c1)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N05 compound treatment 0.341 0.0141 0.55 0.343 0.0164 0.34 0.6342 0.9739 1567994 IFLab1_000643 NC(=O)c1cc2cccc(CC=C)c2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N06 compound treatment 0.373 0.0461 1.81 0.379 0.0524 1.1 2.0566 0.9712 1661386 IFLab1_000644 CCc1cc2c(=O)c(coc2cc1O)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N07 compound treatment 0.368 0.0411 1.61 0.369 0.0424 0.89 1.7696 0.9604 1425226 IFLab1_000645 NC1=C(C#N)C(C2CCCCC2)c3c(O1)c4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N08 compound treatment 0.344 0.0171 0.67 0.37 0.0434 0.91 1.1171 0.9888 1145802 IFLab1_000646 CCc1cc(c(O)cc1OC)c2nc(N)ncc2c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N09 compound treatment 0.363 0.0361 1.42 0.359 0.0324 0.68 1.4826 0.9431 1641303 IFLab1_000647 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N10 compound treatment 0.384 0.0571 2.24 0.374 0.0474 0.99 2.2884 0.9327 1469406 IFLab1_000648 COc1ccc(C(=O)Cc2ccc3OCCOc3c2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N11 compound treatment 0.369 0.0421 1.65 0.357 0.0304 0.64 1.6198 0.914 2066119 IFLab1_000649 O=C(OCc1nc2ccccc2s1)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N12 compound treatment 0.352 0.0251 0.99 0.361 0.0344 0.72 1.2064 0.9882 1178007 IFLab1_000650 COc1ccc(c2n[nH]cc2c3cnc(C)s3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N13 compound treatment 0.334 0.00706 0.28 0.356 0.0294 0.62 0.6319 0.9352 1518256 IFLab1_000651 Cc1noc(c1c2ccc3OCCCOc3c2)c4ccc(O)cc4O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N14 compound treatment 0.266 -0.0609 -2.4 0.262 -0.0646 -1.35 -2.6495 -0.9632 2066120 IFLab1_000652 CC(C)c1nc(C)cc(SCNC(=O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N15 compound treatment 0.332 0.00506 0.2 0.347 0.0204 0.43 0.4432 0.9394 1120486 IFLab1_000653 COc1cccc(Oc2coc3cc(O)ccc3c2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N16 compound treatment 0.348 0.0211 0.83 0.335 0.00844 0.18 0.7104 0.839 2066121 IFLab1_000654 CCOC(=O)c1sc(NC2=NCCCCC2)nc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N17 compound treatment 0.362 0.0351 1.38 0.362 0.0354 0.74 1.4992 0.9577 2066122 IFLab1_000655 Oc1ccc2c(=O)c(c3ccc4OCCOc4c3)c(oc2c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N18 compound treatment 0.399 0.0721 2.83 0.396 0.0694 1.45 3.031 0.9519 2066123 IFLab1_000656 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cccc(c3)C(=O)O)/c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N19 compound treatment 0.394 0.0671 2.64 0.387 0.0604 1.26 2.7588 0.9434 2066124 IFLab1_000657 Cc1csc(n1)c2c(oc3cc(O)c(C)cc3c2=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N20 compound treatment 0.35 0.0231 0.91 0.349 0.0224 0.47 0.9732 0.9531 2066125 IFLab1_000658 COc1ccc(/C=C\2/SC(=S)N(CC(=O)NCc3ccccc3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N21 compound treatment 0.348 0.0211 0.83 0.35 0.0234 0.49 0.9324 0.9687 1409498 IFLab1_000659 Cc1csc(n1)c2c(C)oc3cc(O)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N22 compound treatment 0.385 0.0581 2.28 0.376 0.0494 1.03 2.3458 0.9359 2066126 IFLab1_000660 COc1ccc(/C=C\2/SC(=O)N(CCC(=O)O)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N23 mock treatment 0.33 0.00306 0.12 0.332 0.00544 0.11 0.1656 0.9996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 N24 positive control 0.088 -0.239 -9.39 0.09 -0.237 -4.95 -10.1434 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O01 compound treatment 0.339 0.0121 0.47 0.331 0.00444 0.09 0.401 0.8298 2066127 IFLab1_000661 Cc1ccc(SCc2nc3ncccn3c2Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O02 compound treatment 0.338 0.0111 0.43 0.346 0.0194 0.41 0.5952 0.9994 2066128 IFLab1_000662 COc1ccc(NC2CC(=O)N(C2=O)c3ccccc3C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O03 compound treatment 0.345 0.0181 0.71 0.348 0.0214 0.45 0.8194 0.9755 2066129 IFLab1_000663 CSc1nc2cc(NC(=O)c3cccs3)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O04 compound treatment 0.346 0.0191 0.75 0.359 0.0324 0.68 1.01 0.9988 2066130 IFLab1_000664 Cc1nc2cc(NC(=O)c3ccc(Br)s3)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O05 compound treatment 0.34 0.0131 0.51 0.336 0.00944 0.2 0.5028 0.9138 1429139 IFLab1_000665 CNC(=O)c1cc2ccccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O06 compound treatment 0.338 0.0111 0.43 0.336 0.00944 0.2 0.4472 0.9362 1210621 IFLab1_000666 Clc1ccc(OC(=O)c2ccco2)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O07 compound treatment 0.386 0.0591 2.32 0.383 0.0564 1.18 2.4772 0.9508 1131108 IFLab1_000667 COc1ccc2oc(=O)c(cc2c1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O08 compound treatment 0.369 0.0421 1.65 0.36 0.0334 0.7 1.6642 0.9267 2066131 IFLab1_000668 NC(=N)SCc1cn2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O09 compound treatment 0.359 0.0321 1.26 0.351 0.0244 0.51 1.253 0.9211 2066132 IFLab1_000669 Nc1nc(nc(c1C#N)C(F)(F)F)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O10 compound treatment 0.37 0.0431 1.69 0.393 0.0664 1.39 2.1803 0.9952 1442636 IFLab1_000670 Cc1ccc(cc1)c2nc(C#N)c(NCc3ccco3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O11 compound treatment 0.357 0.0301 1.18 0.34 0.0134 0.28 1.0346 0.8516 1126167 IFLab1_000671 CC(C)NCC(O)COc1ccc2ccccc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O12 compound treatment 0.354 0.0271 1.06 0.359 0.0324 0.68 1.2324 0.9764 1255431 IFLab1_000672 CC1(C)CC(=O)c2sc(NC(=O)c3ccc(F)cc3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O13 compound treatment 0.355 0.0281 1.1 0.355 0.0284 0.6 1.201 0.958 1284522 IFLab1_000673 COc1ccc(cc1)c2[nH]c(=N)sc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O14 compound treatment 0.355 0.0281 1.1 0.356 0.0294 0.62 1.2158 0.9621 1492827 IFLab1_000674 Cc1cc(O)nc(SC(C(=O)O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O15 compound treatment 0.343 0.0161 0.63 0.347 0.0204 0.43 0.749 0.982 2066133 IFLab1_000675 FC(F)(F)Sc1ccc(NC(=O)C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O16 compound treatment 0.344 0.0171 0.67 0.344 0.0174 0.36 0.7324 0.959 1604786 IFLab1_000676 OC(=O)C(Sc1ncccn1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O17 compound treatment 0.347 0.0201 0.79 0.345 0.0184 0.39 0.8306 0.9459 1131927 IFLab1_000677 CCc1ccc(cc1)C(=O)Oc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O18 compound treatment 0.373 0.0461 1.81 0.384 0.0574 1.2 2.1305 0.9802 1192767 IFLab1_000678 Clc1ccc(cc1)C(=O)Nc2nc(=S)ss2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O19 compound treatment 0.363 0.0361 1.42 0.349 0.0224 0.47 1.3346 0.8935 1280949 IFLab1_000679 CC(C)C(=O)Nc1sc2CCC(C)Cc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O20 compound treatment 0.334 0.00706 0.28 0.333 0.00644 0.13 0.2916 0.9448 1375435 IFLab1_000680 COc1ccc(cc1)c2c(C)sc(=NCCO)n2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O21 compound treatment 0.342 0.0151 0.59 0.341 0.0144 0.3 0.6324 0.9512 1343193 IFLab1_000681 COc1cccc(OCC(=O)NC(C)C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O22 compound treatment 0.35 0.0231 0.91 0.354 0.0274 0.57 1.0472 0.9757 1428115 IFLab1_000682 Cc1cccc(c1)C(=O)Nc2nnc(s2)c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O23 mock treatment 0.325 -0.00194 -0.08 0.33 0.00344 0.07 -0.003 -0.0286 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 O24 positive control 0.091 -0.236 -9.28 0.093 -0.234 -4.89 -10.0156 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P01 compound treatment 0.34 0.0131 0.51 0.346 0.0194 0.41 0.6508 0.9933 2066134 IFLab1_000683 CSc1nc(O)cc(NC(=O)C(F)(F)F)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P02 compound treatment 0.344 0.0171 0.67 0.344 0.0174 0.36 0.7324 0.959 1734927 IFLab1_000684 CC(=O)Oc1ccc2c(=O)c(Oc3ccc(Cl)cc3)coc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P03 compound treatment 0.345 0.0181 0.71 0.351 0.0244 0.51 0.8638 0.987 1313753 IFLab1_000685 Cc1ccccc1S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P04 compound treatment 0.372 0.0451 1.77 0.366 0.0394 0.83 1.8364 0.9395 1477934 IFLab1_000686 COc1ccc2c(=O)c(coc2c1C)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P05 compound treatment 0.381 0.0541 2.13 0.379 0.0524 1.1 2.279 0.9527 2066135 IFLab1_000687 O=C/1N\C(=N\c2ccccc2)\S\C1=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P06 compound treatment 0.38 0.0531 2.09 0.378 0.0514 1.08 2.2364 0.9526 1658364 IFLab1_000688 CCc1cc2c(=O)c(coc2c(CN(C)C)c1O)c3cscn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P07 compound treatment 0.403 0.0761 2.99 0.4 0.0734 1.54 3.2014 0.9521 2066136 IFLab1_000689 NC1=C(C#N)C(CCc2ccccc2)c3c(O1)c4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P08 compound treatment 0.404 0.0771 3.03 0.397 0.0704 1.47 3.1848 0.9452 1918579 IFLab1_000690 COc1ccc2c(=O)c(coc2c1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P09 compound treatment 0.39 0.0631 2.48 0.407 0.0804 1.68 2.9435 0.9822 2066137 IFLab1_000691 CCc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P10 compound treatment 0.381 0.0541 2.13 0.39 0.0634 1.33 2.4417 0.9743 1241693 IFLab1_000692 CCCc1cc2c(=O)c(c(C)oc2cc1O)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P11 compound treatment 0.398 0.0711 2.79 0.392 0.0654 1.37 2.944 0.9461 2066138 IFLab1_000693 COc1ccc(cc1OC)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P12 compound treatment 0.381 0.0541 2.13 0.382 0.0554 1.16 2.3234 0.9594 1249520 IFLab1_000694 CC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P13 compound treatment 0.393 0.0661 2.6 0.375 0.0484 1.01 2.5534 0.9158 1550204 IFLab1_000695 Cc1oc2cc(OCC#N)ccc2c(=O)c1c3ccc4OCCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P14 compound treatment 0.372 0.0451 1.77 0.378 0.0514 1.08 2.014 0.9715 1636441 IFLab1_000696 Fc1ccc(NC2CC(=O)N(Cc3ccccc3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P15 compound treatment 0.379 0.0521 2.05 0.381 0.0544 1.14 2.253 0.9617 1455221 IFLab1_000697 Oc1cc(O)c2c(=O)c(Oc3ccc(F)cc3)coc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P16 compound treatment 0.455 0.128 5.04 0.462 0.135 2.83 5.5645 0.963 2066139 IFLab1_000698 OC(=O)CCCN1C(=O)/C(=C/c2ccc(Cl)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P17 compound treatment 0.355 0.0281 1.1 0.358 0.0314 0.66 1.2454 0.9695 1492285 IFLab1_000699 Oc1cc(O)c2c(=O)c(coc2c1)c3ccc4OCCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P18 compound treatment 0.515 0.188 7.39 0.625 0.298 6.25 9.6445 0.9965 1922325 IFLab1_000700 OC(=O)CN1C(=O)/C(=C/C=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P19 compound treatment 0.364 0.0371 1.46 0.378 0.0514 1.08 1.7915 0.9889 1387348 IFLab1_000701 Oc1cc(O)c2c(=O)c(coc2c1)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P20 compound treatment 0.36 0.0331 1.3 0.356 0.0294 0.62 1.3548 0.9418 2066140 IFLab1_000702 CN1CCN(CC1)C(=O)CN2C(=O)S/C(=C\c3ccc(Cl)cc3)/C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P21 compound treatment 0.372 0.0451 1.77 0.366 0.0394 0.83 1.8364 0.9395 1608146 IFLab1_000703 CCc1cc(c2n[nH]cc2c3ccc4OCCOc4c3)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P22 compound treatment 0.401 0.0741 2.91 0.399 0.0724 1.52 3.131 0.9537 2066141 IFLab1_000704 O=C1NC(=O)/C(=C\C=C\c2ccccc2)/S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P23 mock treatment 0.344 0.0171 0.67 0.333 0.00644 0.13 0.5696 0.8325 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1413 P24 positive control 0.093 -0.234 -9.2 0.096 -0.231 -4.82 -9.9156 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A01 compound treatment 0.346 0.0181 0.71 0.346 0.0206 0.43 0.8091 0.9711 2066142 IFLab1_000705 COc1ccccc1/C=C/2\SC(=S)N(CCC(=O)Nc3nccs3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A02 compound treatment 0.321 -0.00688 -0.27 0.335 0.00962 0.2 -0.0487 -0.1445 2066143 IFLab1_000706 Nc1c(C#N)cnn1c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A03 compound treatment 0.241 -0.0869 -3.42 0.253 -0.0724 -1.51 -3.4862 -0.933 2066144 IFLab1_000707 CCOc1cc(/C=C/2\SC(=S)N(C2=O)c3ccccc3)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A04 compound treatment 0.34 0.0121 0.48 0.348 0.0226 0.47 0.6719 1.0 2066145 IFLab1_000708 O=c1[nH]c(nc2sc3CCCCc3c12)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A05 compound treatment 0.322 -0.00588 -0.23 0.316 -0.00938 -0.2 -0.3021 -0.9967 1582407 IFLab1_000709 NC(=O)c1cc(Cl)c(cc1Cl)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A06 compound treatment 0.327 -8.75E-4 -0.03 0.326 6.25E-4 0.01 -0.0151 -0.4097 2066146 IFLab1_000710 CCc1nc2sc3CCCCc3c2c4nncn14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A07 compound treatment 0.331 0.00312 0.12 0.313 -0.0124 -0.26 -0.0962 -0.3357 1178646 IFLab1_000711 Cc1onc(c1C(=O)NCC2COc3ccccc3O2)c4ccccc4Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A08 compound treatment 0.334 0.00612 0.24 0.328 0.00262 0.05 0.2091 0.8467 1144144 IFLab1_000712 O=c1[nH]cnc2n(ncc12)c3ccc4ccccc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A09 compound treatment 0.309 -0.0189 -0.74 0.31 -0.0154 -0.32 -0.7523 -0.93 1696434 IFLab1_000713 Cc1nc2ccccc2nc1SCC(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A10 compound treatment 0.324 -0.00388 -0.15 0.314 -0.0114 -0.24 -0.276 -0.9768 1293363 IFLab1_000714 OC(=O)CCC(=O)Nc1ccccc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A11 compound treatment 0.328 1.25E-4 0.0 0.324 -0.00138 -0.03 -0.0169 -0.578 2066147 IFLab1_000715 CCC(=O)N=c1sc2cc(C)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A12 compound treatment 0.355 0.0271 1.07 0.352 0.0266 0.56 1.1481 0.9542 1443857 IFLab1_000716 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A13 compound treatment 0.336 0.00812 0.32 0.331 0.00562 0.12 0.3091 0.908 1209496 IFLab1_000717 CCCOc1ccccc1N2C(=O)CC(N(O)c3ccccc3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A14 compound treatment 0.342 0.0141 0.56 0.337 0.0116 0.24 0.5647 0.9314 1915651 IFLab1_000718 OC(=O)c1cc(nc2C(=O)C=C(O)C(=O)c12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A15 compound treatment 0.464 0.136 5.35 0.451 0.126 2.63 5.6434 0.9464 1191019 IFLab1_000719 Oc1ccc2cc(c3ccccn3)c(=O)oc2c1CN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A16 compound treatment 0.348 0.0201 0.79 0.346 0.0206 0.43 0.8647 0.9594 2066148 IFLab1_000720 OC(=O)CCCNC1=NCCS1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A17 compound treatment 0.33 0.00212 0.08 0.323 -0.00238 -0.05 0.0239 0.2462 2066149 IFLab1_000721 Brc1ccc(cc1)C(=O)COC(=O)c2cc3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A18 compound treatment 0.317 -0.0109 -0.43 0.323 -0.00238 -0.05 -0.3375 -0.784 2066150 IFLab1_000722 NCCCc1nc2cc(Cc3ccc4[nH]c(CCCN)nc4c3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A19 compound treatment 0.321 -0.00688 -0.27 0.325 -3.75E-4 -0.01 -0.1967 -0.7273 1582593 IFLab1_000723 O=C(COC(=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A20 compound treatment 0.34 0.0121 0.48 0.339 0.0136 0.29 0.5387 0.9698 1178732 IFLab1_000724 CCOC(=O)c1ccccc1NCn2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A21 compound treatment 0.318 -0.00988 -0.39 0.32 -0.00538 -0.11 -0.3541 -0.8759 2066151 IFLab1_000725 COc1ncnc2sc3CCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A22 compound treatment 0.319 -0.00888 -0.35 0.32 -0.00538 -0.11 -0.3263 -0.8899 2066152 IFLab1_000726 CCOc1ccccc1NC(=O)CC2SC(=N)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A23 mock treatment 0.318 -0.00988 -0.39 0.319 -0.00638 -0.13 -0.3689 -0.8985 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 A24 positive control 0.078 -0.25 -9.82 0.078 -0.247 -5.18 -10.6075 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B01 compound treatment 0.332 0.00412 0.16 0.346 0.0206 0.43 0.4199 0.9106 1435318 IFLab1_000727 COc1ccc(NC(=O)COc2cccc(Oc3ccccc3)c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B02 compound treatment 0.316 -0.0119 -0.47 0.315 -0.0104 -0.22 -0.4837 -0.9393 2066153 IFLab1_000728 Cc1nc2cc(ccc2s1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B03 compound treatment 0.322 -0.00588 -0.23 0.319 -0.00638 -0.13 -0.2577 -0.966 1236739 IFLab1_000729 CCOc1ccc(OCC)c(c1)S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B04 compound treatment 0.327 -8.75E-4 -0.03 0.325 -3.75E-4 -0.01 -0.0299 -0.8467 1357115 IFLab1_000730 Cc1ncc(CN2CCOCC2)c(N)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B05 compound treatment 0.326 -0.00188 -0.07 0.317 -0.00838 -0.18 -0.1761 -0.926 1153755 IFLab1_000731 COc1cccc(OC)c1C(=O)Oc2cccc3ccc(C)nc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B06 compound treatment 0.319 -0.00888 -0.35 0.325 -3.75E-4 -0.01 -0.2523 -0.7228 1656336 IFLab1_000732 O=C(Nc1nc2CCCCc2s1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B07 compound treatment 0.337 0.00912 0.36 0.329 0.00362 0.08 0.3073 0.8381 1340351 IFLab1_000733 CN1CCN(CC1)S(=O)(=O)c2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B08 compound treatment 0.339 0.0111 0.44 0.325 -3.75E-4 -0.01 0.3037 0.6943 1331391 IFLab1_000734 COc1ccccc1NC(=O)CCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B09 compound treatment 0.334 0.00612 0.24 0.328 0.00262 0.05 0.2091 0.8467 1166622 IFLab1_000735 COc1ccc(cc1)S(=O)(=O)n2ccnc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B10 compound treatment 0.348 0.0201 0.79 0.335 0.00962 0.2 0.7019 0.8597 1632537 IFLab1_000736 Cc1ccc(cc1)c2nc(nc3ccccc23)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B11 compound treatment 0.335 0.00712 0.28 0.328 0.00262 0.05 0.2369 0.83 2066154 IFLab1_000737 CC(=O)Nc1sc(C)nc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B12 compound treatment 0.337 0.00912 0.36 0.331 0.00562 0.12 0.3369 0.8923 1345692 IFLab1_000738 CCS(=O)(=O)c1ccc(O)c(c1)N2C(=O)c3cccc4cccc(C2=O)c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B13 compound treatment 0.338 0.0101 0.4 0.334 0.00862 0.18 0.4091 0.936 1144948 IFLab1_000739 Cc1ccc(Nc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B14 compound treatment 0.343 0.0151 0.59 0.347 0.0216 0.45 0.7405 0.9909 1625199 IFLab1_000740 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B15 compound treatment 0.32 -0.00788 -0.31 0.321 -0.00438 -0.09 -0.2837 -0.8786 2066155 IFLab1_000741 CC(C)CC1C(=C(N)OC2=C1C(=O)CC(C2)c3ccccc3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B16 compound treatment 0.331 0.00312 0.12 0.332 0.00662 0.14 0.1849 0.9982 2066156 IFLab1_000742 OC(=O)/C=C/C(=O)NC1CCCC(C1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B17 compound treatment 0.346 0.0181 0.71 0.317 -0.00838 -0.18 0.38 0.5178 2066157 IFLab1_000743 Cc1c(C#N)c(N)nc(SCC(=O)N)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B18 compound treatment 0.326 -0.00188 -0.07 0.332 0.00662 0.14 0.0459 0.2923 2066158 IFLab1_000744 FC(F)(F)c1cccc(c1)N2CCN(CC2)S(=O)(=O)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B19 compound treatment 0.328 1.25E-4 0.0 0.328 0.00262 0.05 0.0423 0.7673 1262898 IFLab1_000745 CSc1nc(cc(c1C#N)c2ccccc2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B20 compound treatment 0.339 0.0111 0.44 0.334 0.00862 0.18 0.4369 0.9234 1093273 IFLab1_000746 Cc1cc(C)n(n1)c2ccc(Cl)nn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B21 compound treatment 0.334 0.00612 0.24 0.339 0.0136 0.29 0.3719 0.9965 2066159 IFLab1_000747 CN(C)C(=O)c1cc(F)c(F)c(F)c1F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B22 compound treatment 0.333 0.00512 0.2 0.334 0.00862 0.18 0.2701 0.9985 2066160 IFLab1_000748 O=C(CSc1nnc2ccccn12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B23 mock treatment 0.333 0.00512 0.2 0.327 0.00162 0.03 0.1665 0.8149 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 B24 positive control 0.078 -0.25 -9.82 0.078 -0.247 -5.18 -10.6075 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C01 compound treatment 0.339 0.0111 0.44 0.342 0.0166 0.35 0.5553 0.9936 2066161 IFLab1_000749 COc1cccc(/C=C\2/SC(=S)N(CCC(=O)N3CCCCC3)C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C02 compound treatment 0.337 0.00912 0.36 0.34 0.0146 0.31 0.4701 0.9969 2066162 IFLab1_000750 CN(C)CCCNc1ncnc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C03 compound treatment 0.334 0.00612 0.24 0.337 0.0116 0.24 0.3423 1.0 2066163 IFLab1_000751 COc1ccc(/C=C/2\SC(=O)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C04 compound treatment 0.358 0.0301 1.18 0.34 0.0146 0.31 1.0539 0.8615 1336422 IFLab1_000752 O=C(N1CCCCC1)c2ccc3SCC(=O)Nc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C05 compound treatment 0.316 -0.0119 -0.47 0.325 -3.75E-4 -0.01 -0.3357 -0.7189 2066164 IFLab1_000753 Cc1nnc(SCC(=O)c2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C06 compound treatment 0.336 0.00812 0.32 0.32 -0.00538 -0.11 0.1464 0.4321 1387926 IFLab1_000754 CCN1CCN(CC1)c2nc(C)nc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C07 compound treatment 0.312 -0.0159 -0.62 0.329 0.00362 0.08 -0.3877 -0.6166 2066165 IFLab1_000755 OC(=O)CSc1nc(ccc1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C08 compound treatment 0.326 -0.00188 -0.07 0.323 -0.00238 -0.05 -0.0873 -0.9816 1179581 IFLab1_000756 O=C(Cc1ccccc1)Oc2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C09 compound treatment 0.333 0.00512 0.2 0.324 -0.00138 -0.03 0.1221 0.6 1679237 IFLab1_000757 O=C(CSc1ncnc2ccccc12)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C10 compound treatment 0.321 -0.00688 -0.27 0.329 0.00362 0.08 -0.1375 -0.4898 2066166 IFLab1_000758 CCCSc1nc(C)cc(O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C11 compound treatment 0.345 0.0171 0.67 0.322 -0.00338 -0.07 0.4262 0.6295 2066167 IFLab1_000759 CC(C)C(=O)N=c1sc2cc(C)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C12 compound treatment 0.336 0.00812 0.32 0.334 0.00862 0.18 0.3535 0.9635 1211734 IFLab1_000760 Oc1ccc(cc1)c2ccc(C#N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C13 compound treatment 0.336 0.00812 0.32 0.339 0.0136 0.29 0.4275 0.9984 2066168 IFLab1_000761 Fc1ccc(/C=C/C(=O)Nc2nc3ccccc3s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C14 compound treatment 0.333 0.00512 0.2 0.337 0.0116 0.24 0.3145 0.9956 1247012 IFLab1_000762 Cc1ccc(cc1)S(=O)(=O)N2CCn3c(C2)nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C15 compound treatment 0.32 -0.00788 -0.31 0.333 0.00762 0.16 -0.1061 -0.3046 1378201 IFLab1_000763 CCc1sc(=N)[nH]c1c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C16 compound treatment 0.336 0.00812 0.32 0.321 -0.00438 -0.09 0.1612 0.4849 1013636 IFLab1_000764 OC(=O)c1cc2ccccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C17 compound treatment 0.339 0.0111 0.44 0.342 0.0166 0.35 0.5553 0.9936 2066169 IFLab1_000765 CCN(CC)c1ccc(/C=N/c2nc3CCCCc3s2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C18 compound treatment 0.335 0.00712 0.28 0.335 0.00962 0.2 0.3405 0.9869 1196090 IFLab1_000766 CCCCc1ccc(cc1)c2nc3ccccc3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C19 compound treatment 0.363 0.0351 1.38 0.361 0.0356 0.75 1.5037 0.9581 1605525 IFLab1_000767 NC(=O)c1ccsc1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C20 compound treatment 0.336 0.00812 0.32 0.338 0.0126 0.26 0.4127 0.9955 1589089 IFLab1_000768 NC(=O)c1cc2ccccc2oc1=Nc3ccc(Cl)cc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C21 compound treatment 0.327 -8.75E-4 -0.03 0.312 -0.0134 -0.28 -0.2222 -0.7881 1072653 IFLab1_000769 NC(=O)c1c(N)sc2CCCCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C22 compound treatment 0.335 0.00712 0.28 0.335 0.00962 0.2 0.3405 0.9869 1427875 IFLab1_000770 OC(=O)c1ccccc1SC2CC(=O)N(C2=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C23 mock treatment 0.325 -0.00288 -0.11 0.323 -0.00238 -0.05 -0.1151 -0.9319 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 C24 positive control 0.079 -0.249 -9.79 0.078 -0.247 -5.18 -10.5797 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D01 compound treatment 0.216 -0.112 -4.4 0.222 -0.103 -2.16 -4.64 -0.9466 1336894 IFLab1_000771 CCOC(=O)c1[nH]c(COC(=O)C)c(CC)c1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D02 compound treatment 0.325 -0.00288 -0.11 0.33 0.00462 0.1 -0.0115 -0.0772 2066170 IFLab1_000772 FC(F)(F)Sc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D03 compound treatment 0.333 0.00512 0.2 0.337 0.0116 0.24 0.3145 0.9956 1628546 IFLab1_000773 COc1cc(c(OC)cc1Cl)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D04 compound treatment 0.327 -8.75E-4 -0.03 0.321 -0.00438 -0.09 -0.0891 -0.9106 1343364 IFLab1_000774 CC(=O)Nc1cc2ccccc2cc1NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D05 compound treatment 0.333 0.00512 0.2 0.341 0.0156 0.33 0.3737 0.973 1355529 IFLab1_000775 CCOc1ccc2cc(ccc2c1)S(=O)(=O)N3CCN(C)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D06 compound treatment 0.329 0.00112 0.04 0.33 0.00462 0.1 0.0997 0.937 1619282 IFLab1_000776 Brc1ccc(NC(=O)c2ccco2)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D07 compound treatment 0.329 0.00112 0.04 0.323 -0.00238 -0.05 -0.0039 -0.0581 2066171 IFLab1_000777 Cc1cn(cn1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D08 compound treatment 0.657 0.329 12.94 0.621 0.296 6.19 13.5247 0.9429 1626796 IFLab1_000778 Cc1ccc(NC(=S)SCCC(=O)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D09 compound treatment 0.344 0.0161 0.63 0.335 0.00962 0.2 0.5907 0.888 2066172 IFLab1_000779 CC1=C(C)C/S(=N\c2ccccc2)/N(C1)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D10 compound treatment 0.338 0.0101 0.4 0.339 0.0136 0.29 0.4831 0.9866 1774660 IFLab1_000780 OC(=O)CNS(=O)(=O)/C=C/c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D11 compound treatment 0.346 0.0181 0.71 0.342 0.0166 0.35 0.7499 0.9456 1567659 IFLab1_000781 CC(=O)Nc1c(nc2ccccn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D12 compound treatment 0.343 0.0151 0.59 0.326 6.25E-4 0.01 0.4298 0.7225 1334752 IFLab1_000782 OP(=O)(C1CCCCN1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D13 compound treatment 0.341 0.0131 0.52 0.319 -0.00638 -0.13 0.2706 0.5076 1558592 IFLab1_000783 COc1ccc(Nc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D14 compound treatment 0.328 1.25E-4 0.0 0.33 0.00462 0.1 0.0719 0.7421 1453859 IFLab1_000784 O=S(=O)(N1CCC2CCCCC2C1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D15 compound treatment 0.33 0.00212 0.08 0.338 0.0126 0.26 0.2459 0.8874 1351496 IFLab1_000785 COC(=O)C1C(C(=C(NC1=O)SC)C#N)c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D16 compound treatment 0.345 0.0171 0.67 0.341 0.0156 0.33 0.7073 0.945 2066173 IFLab1_000786 O=C(CSc1nnc2ccccn12)Nc3sc4CCCCc4c3C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D17 compound treatment 0.404 0.0761 2.99 0.404 0.0786 1.65 3.2799 0.9603 1567187 IFLab1_000787 NC1=C(C#N)C(Cc2ccccc2)C(=C(N)S1)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D18 compound treatment 0.338 0.0101 0.4 0.336 0.0106 0.22 0.4387 0.9621 1729782 IFLab1_000788 c1ccc2c3nnnn3c(nc2c1)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D19 compound treatment 0.375 0.0471 1.85 0.371 0.0456 0.95 1.9853 0.9525 1391339 IFLab1_000789 Nc1c(C#N)c(cc(c1C#N)c2ccccc2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D20 compound treatment 0.339 0.0111 0.44 0.342 0.0166 0.35 0.5553 0.9936 2066174 IFLab1_000790 CCOc1ccc2N3CCS(=O)(=O)N=C3Sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D21 compound treatment 0.355 0.0271 1.07 0.361 0.0356 0.75 1.2813 0.9847 2066175 IFLab1_000791 CCN1C(=O)/C(=C/N(C(=O)C)c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D22 compound treatment 0.338 0.0101 0.4 0.342 0.0166 0.35 0.5275 0.9977 2066176 IFLab1_000792 O=C(/C=C/c1ccco1)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D23 mock treatment 0.324 -0.00388 -0.15 0.327 0.00162 0.03 -0.0837 -0.5361 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 D24 positive control 0.08 -0.248 -9.75 0.079 -0.246 -5.16 -10.5371 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E01 compound treatment 0.33 0.00212 0.08 0.338 0.0126 0.26 0.2459 0.8874 2066177 IFLab1_000793 COc1ccc(/C=C\2/SC(=S)N(CCC(=O)Nc3nccs3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E02 compound treatment 0.319 -0.00888 -0.35 0.333 0.00762 0.16 -0.1339 -0.349 1215246 IFLab1_000794 Cc1cccc(NS(=O)(=O)c2ccc3OCCOc3c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E03 compound treatment 0.369 0.0411 1.62 0.365 0.0396 0.83 1.7297 0.9519 2066178 IFLab1_000795 CN(C)c1ccc(/C=C/2\SC(=O)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E04 compound treatment 0.33 0.00212 0.08 0.342 0.0166 0.35 0.3051 0.8527 1917636 IFLab1_000796 C(CSc1nc2ccccc2s1)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E05 compound treatment 0.337 0.00912 0.36 0.324 -0.00138 -0.03 0.2333 0.6483 2066179 IFLab1_000797 COc1ccc(cc1)c2ccnc(SCC(=O)c3ccc(Cl)cc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E06 compound treatment 0.362 0.0341 1.34 0.349 0.0236 0.49 1.2983 0.908 1382086 IFLab1_000798 COc1ccc2c(C)cc(nc2c1)n3nc(C)cc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E07 compound treatment 0.337 0.00912 0.36 0.336 0.0106 0.22 0.4109 0.9735 2066180 IFLab1_000799 Cc1ccc(C#N)c(SC(C(=O)O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E08 compound treatment 0.347 0.0191 0.75 0.346 0.0206 0.43 0.8369 0.9653 2066181 IFLab1_000800 OC(=O)CSc1ccc2ccccc2c1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E09 compound treatment 0.346 0.0181 0.71 0.342 0.0166 0.35 0.7499 0.9456 2066182 IFLab1_000801 CC(C)C(=O)Nc1nc(cs1)c2ccc(Br)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E10 compound treatment 0.348 0.0201 0.79 0.344 0.0186 0.39 0.8351 0.9468 1241077 IFLab1_000802 O=S(=O)(CCc1nc2ccccc2[nH]1)CCc3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E11 compound treatment 0.352 0.0241 0.95 0.346 0.0206 0.43 0.9759 0.9365 2066183 IFLab1_000803 Cc1ccc2n(C)c(=NC(=O)c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E12 compound treatment 0.349 0.0211 0.83 0.34 0.0146 0.31 0.8037 0.908 1003071 IFLab1_000804 OC(=O)CCC(=O)c1ccc2ccccc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E13 compound treatment 0.342 0.0141 0.56 0.336 0.0106 0.22 0.5499 0.9193 1439444 IFLab1_000805 O=C(c1ccc(cc1)S(=O)(=O)N2CCCCC2)n3cnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E14 compound treatment 0.338 0.0101 0.4 0.336 0.0106 0.22 0.4387 0.9621 1167767 IFLab1_000806 Cc1nc2cc(CO)ccc2n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E15 compound treatment 0.34 0.0121 0.48 0.34 0.0146 0.31 0.5535 0.977 2066184 IFLab1_000807 O=C(C/N=C/1\CCCN1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E16 compound treatment 0.341 0.0131 0.52 0.338 0.0126 0.26 0.5517 0.9517 1467897 IFLab1_000808 COC(=O)c1cccc(n1)C(=O)Oc2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E17 compound treatment 0.337 0.00912 0.36 0.33 0.00462 0.1 0.3221 0.8669 1553040 IFLab1_000809 COC(=O)C(NC(=O)c1cccs1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E18 compound treatment 0.336 0.00812 0.32 0.341 0.0156 0.33 0.4571 0.9999 1175330 IFLab1_000810 O=C(NCc1nc2ccccc2[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E19 compound treatment 0.332 0.00412 0.16 0.339 0.0136 0.29 0.3163 0.9642 2066185 IFLab1_000811 CC(N)(C(=O)O)c1cccc(OCc2cccc(Cl)c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E20 compound treatment 0.339 0.0111 0.44 0.343 0.0176 0.37 0.5701 0.9964 1920319 IFLab1_000812 Brc1ccc(o1)C(=O)Nc2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E21 compound treatment 0.344 0.0161 0.63 0.344 0.0186 0.39 0.7239 0.9727 1543687 IFLab1_000813 NS(=O)(=O)c1ccc2OCCOc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E22 compound treatment 0.34 0.0121 0.48 0.335 0.00962 0.2 0.4795 0.9266 2066186 IFLab1_000814 FC(F)(F)c1ccccc1N2C(=O)CC(Nc3ccc(cc3)N4CCOCC4)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E23 mock treatment 0.328 1.25E-4 0.0 0.326 6.25E-4 0.01 0.0127 0.9106 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 E24 positive control 0.081 -0.247 -9.71 0.081 -0.244 -5.11 -10.4797 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F01 compound treatment 0.344 0.0161 0.63 0.338 0.0126 0.26 0.6351 0.9247 1457970 IFLab1_000815 COc1ccc(cc1OC)S(=O)(=O)n2cnc3cc(C)c(C)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F02 compound treatment 0.319 -0.00888 -0.35 0.324 -0.00138 -0.03 -0.2671 -0.7628 2066187 IFLab1_000816 Fc1c(F)c(F)c(Nc2ccccc2)c(F)c1F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F03 compound treatment 0.358 0.0301 1.18 0.342 0.0166 0.35 1.0835 0.8777 1382541 IFLab1_000817 COc1ccc(Nc2ncc(s2)c3cc4cc(OC)ccc4oc3=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F04 compound treatment 0.366 0.0381 1.5 0.374 0.0486 1.02 1.7795 0.9822 1673434 IFLab1_000818 CCN1C(=O)c2cccc3c(NC(=O)C(C)(C)C)ccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F05 compound treatment 0.324 -0.00388 -0.15 0.316 -0.00938 -0.2 -0.2465 -0.9922 1307775 IFLab1_000819 CCOc1ccc2cc(ccc2c1)S(=O)(=O)N3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F06 compound treatment 0.354 0.0261 1.03 0.332 0.00662 0.14 0.8244 0.7953 1707691 IFLab1_000820 COc1cccc(c1)C(=O)Nc2nc(cs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F07 compound treatment 0.337 0.00912 0.36 0.325 -3.75E-4 -0.01 0.2481 0.6915 2066188 IFLab1_000821 Cc1ccccc1C(=O)ON2CCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F08 compound treatment 0.342 0.0141 0.56 0.334 0.00862 0.18 0.5203 0.891 1006473 IFLab1_000822 NC(=O)CCSC(=S)N1CCOCC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F09 compound treatment 0.331 0.00312 0.12 0.33 0.00462 0.1 0.1553 0.993 1721458 IFLab1_000823 CC1=C(C)CS(=O)N(C1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F10 compound treatment 0.349 0.0211 0.83 0.313 -0.0124 -0.26 0.4042 0.4646 1783521 IFLab1_000824 COc1ccccc1NS(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F11 compound treatment 0.341 0.0131 0.52 0.342 0.0166 0.35 0.6109 0.9816 1292240 IFLab1_000825 CC(=O)Nc1sc(N)nc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F12 compound treatment 0.328 1.25E-4 0.0 0.342 0.0166 0.35 0.2495 0.717 1529227 IFLab1_000826 CC(NC(=O)Cc1ccccc1)P(=O)(O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F13 compound treatment 0.346 0.0181 0.71 0.329 0.00362 0.08 0.5576 0.778 1429319 IFLab1_000827 OC(=O)CSc1ccc2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F14 compound treatment 0.342 0.0141 0.56 0.345 0.0196 0.41 0.6831 0.989 1269335 IFLab1_000828 CC1CCCN(Cn2cnc3ccccc23)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F15 compound treatment 0.286 -0.0419 -1.65 0.286 -0.0394 -0.82 -1.7468 -0.9488 1450633 IFLab1_000829 COC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2C)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F16 compound treatment 0.335 0.00712 0.28 0.33 0.00462 0.1 0.2665 0.8992 2066189 IFLab1_000830 C(CSc1nnnn1c2ccccc2)Oc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F17 compound treatment 0.417 0.0891 3.5 0.425 0.0996 2.08 3.952 0.9692 1983965 IFLab1_000831 CC(C)C1C(=C(N)SC(=C1C#N)N)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F18 compound treatment 0.353 0.0251 0.99 0.359 0.0336 0.7 1.1961 0.9862 1209125 IFLab1_000832 COc1ccc(cc1OC)C(=O)Nc2ncnc3sc4CCCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F19 compound treatment 0.356 0.0281 1.11 0.348 0.0226 0.47 1.1167 0.9283 1733805 IFLab1_000833 NC1=C(C#N)C(CC(=C1C#N)C2CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F20 compound treatment 0.335 0.00712 0.28 0.34 0.0146 0.31 0.4145 0.999 1712762 IFLab1_000834 O=S(=O)(Nc1ccccn1)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F21 compound treatment 0.342 0.0141 0.56 0.344 0.0186 0.39 0.6683 0.985 1092401 IFLab1_000835 Cc1ccc(N)c(c1)C(O)(C(F)(F)F)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F22 compound treatment 0.332 0.00412 0.16 0.33 0.00462 0.1 0.1831 0.9696 2066190 IFLab1_000836 OC(=O)CSc1nnc2sc3ccccc3n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F23 mock treatment 0.336 0.00812 0.32 0.327 0.00162 0.03 0.2499 0.778 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 F24 positive control 0.081 -0.247 -9.71 0.081 -0.244 -5.11 -10.4797 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G01 compound treatment 0.344 0.0161 0.63 0.345 0.0196 0.41 0.7387 0.9779 2066191 IFLab1_000837 Cc1ccc(/C=C\2/SC(=S)N(CC(=O)Nc3nccs3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G02 compound treatment 0.313 -0.0149 -0.58 0.316 -0.00938 -0.2 -0.5523 -0.8953 2066192 IFLab1_000838 CCOC(=O)c1cnn(c1N)c2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G03 compound treatment 0.332 0.00412 0.16 0.344 0.0186 0.39 0.3903 0.9245 1180638 IFLab1_000839 CC(C)NC(=O)COc1ccc2ccccc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G04 compound treatment 0.327 -8.75E-4 -0.03 0.324 -0.00138 -0.03 -0.0447 -0.9961 2066193 IFLab1_000840 O=C(CSc1nc2ccccc2s1)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G05 compound treatment 0.313 -0.0149 -0.58 0.323 -0.00238 -0.05 -0.4487 -0.7644 2066194 IFLab1_000841 OC(=O)C(Sc1nnc[nH]1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G06 compound treatment 0.342 0.0141 0.56 0.32 -0.00538 -0.11 0.3132 0.5527 1260123 IFLab1_000842 Oc1ccc(CN2CCOCC2)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G07 compound treatment 0.347 0.0191 0.75 0.338 0.0126 0.26 0.7185 0.9015 2066195 IFLab1_000843 OC(=O)C(Sc1nc(ccc1C#N)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G08 compound treatment 0.322 -0.00588 -0.23 0.323 -0.00238 -0.05 -0.1985 -0.84 1299218 IFLab1_000844 COc1cccc2cc(C(=O)Nc3ccccc3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G09 compound treatment 0.351 0.0231 0.91 0.34 0.0146 0.31 0.8593 0.8957 1112883 IFLab1_000845 CC(=O)Nc1nc-2c(CCc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G10 compound treatment 0.339 0.0111 0.44 0.331 0.00562 0.12 0.3925 0.8666 1919273 IFLab1_000846 CSc1nnc(Nc2ccccc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G11 compound treatment 0.333 0.00512 0.2 0.336 0.0106 0.22 0.2997 0.9988 2066196 IFLab1_000847 CC(=O)N=c1sc2cc(C)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G12 compound treatment 0.333 0.00512 0.2 0.338 0.0126 0.26 0.3293 0.9911 1918502 IFLab1_000848 Nc1ccc(Sc2nc3ccccc3s2)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G13 compound treatment 0.345 0.0171 0.67 0.343 0.0176 0.37 0.7369 0.9599 2066197 IFLab1_000849 OC(=O)c1ccccc1SC/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G14 compound treatment 0.316 -0.0119 -0.47 0.319 -0.00638 -0.13 -0.4245 -0.8742 1273147 IFLab1_000850 N=c1oc2ccccc2cc1c3nc4ccccc4c(=O)[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G15 compound treatment 0.33 0.00212 0.08 0.333 0.00762 0.16 0.1719 0.9544 2066198 IFLab1_000851 CCOc1ccc(cc1)c2cnc3CCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G16 compound treatment 0.33 0.00212 0.08 0.316 -0.00938 -0.2 -0.0796 -0.3735 1346128 IFLab1_000852 COC(=O)c1cccc(n1)C(=O)Nc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G17 compound treatment 0.328 1.25E-4 0.0 0.335 0.00962 0.2 0.1459 0.7241 1707205 IFLab1_000853 COC(=O)C(C)NC(=O)C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G18 compound treatment 0.332 0.00412 0.16 0.332 0.00662 0.14 0.2127 0.9969 1139849 IFLab1_000854 Clc1ccc(cc1)S(=O)(=O)NCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G19 compound treatment 0.32 -0.00788 -0.31 0.337 0.0116 0.24 -0.0469 -0.1192 2066199 IFLab1_000855 OC(=O)Cc1sc(Nc2ccccc2)nc1c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G20 compound treatment 0.328 1.25E-4 0.0 0.333 0.00762 0.16 0.1163 0.7285 2066200 IFLab1_000856 FC(F)(F)c1cccc(NC(=O)c2ccc(Br)o2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G21 compound treatment 0.334 0.00612 0.24 0.33 0.00462 0.1 0.2387 0.9198 2066201 IFLab1_000857 COc1ccc2N3C(=NCCS3(=O)=O)Sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G22 compound treatment 0.321 -0.00688 -0.27 0.313 -0.0124 -0.26 -0.3743 -0.9998 1547942 IFLab1_000858 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G23 mock treatment 0.317 -0.0109 -0.43 0.321 -0.00438 -0.09 -0.3671 -0.8395 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 G24 positive control 0.081 -0.247 -9.71 0.081 -0.244 -5.11 -10.4797 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H01 compound treatment 0.348 0.0201 0.79 0.339 0.0136 0.29 0.7611 0.9049 1539766 IFLab1_000859 Cc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H02 compound treatment 0.33 0.00212 0.08 0.328 0.00262 0.05 0.0979 0.9793 2066202 IFLab1_000860 CC(=O)Nc1cccc(c1)C(C(F)(F)F)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H03 compound treatment 0.323 -0.00488 -0.19 0.321 -0.00438 -0.09 -0.2003 -0.9428 2066203 IFLab1_000861 CCOC(=O)c1c(C)oc(N)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H04 compound treatment 0.383 0.0551 2.17 0.375 0.0496 1.04 2.2669 0.9432 1429241 IFLab1_000862 CC(=O)Nc1ccc(O)c(c1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H05 compound treatment 0.33 0.00212 0.08 0.326 6.25E-4 0.01 0.0683 0.808 1367455 IFLab1_000863 Cc1cccc(c1)C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H06 compound treatment 0.34 0.0121 0.48 0.3 -0.0254 -0.53 -0.0384 -0.0538 2066204 IFLab1_000864 Cc1csc(=NC(=O)c2ccccc2)n1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H07 compound treatment 0.332 0.00412 0.16 0.336 0.0106 0.22 0.2719 0.988 1371413 IFLab1_000865 O=C(Nn1cnnc1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H08 compound treatment 0.36 0.0321 1.26 0.359 0.0336 0.7 1.3907 0.9618 1695119 IFLab1_000866 Fc1cccc(F)c1C(=O)Nc2nc3c(Cl)cccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H09 compound treatment 0.343 0.0151 0.59 0.322 -0.00338 -0.07 0.3706 0.6188 2066205 IFLab1_000867 COC(=O)NC1Sc2ccccc2N=C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H10 compound treatment 0.338 0.0101 0.4 0.331 0.00562 0.12 0.3647 0.8786 1864904 IFLab1_000868 OC(=O)c1ccc(NS(=O)(=O)/C=C/c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H11 compound treatment 0.34 0.0121 0.48 0.336 0.0106 0.22 0.4943 0.9397 2066206 IFLab1_000869 CN=S(=O)(Nc1ccccc1)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H12 compound treatment 0.329 0.00112 0.04 0.333 0.00762 0.16 0.1441 0.8703 1719046 IFLab1_000870 CC(NC(=O)Cc1ccccc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H13 compound treatment 0.338 0.0101 0.4 0.338 0.0126 0.26 0.4683 0.9802 1920032 IFLab1_000871 CCOC(=O)CSc1ccc2ccccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H14 compound treatment 0.345 0.0171 0.67 0.34 0.0146 0.31 0.6925 0.9363 1168264 IFLab1_000872 OC(=O)C1CCN(CC1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H15 compound treatment 0.333 0.00512 0.2 0.339 0.0136 0.29 0.3441 0.9856 1731533 IFLab1_000873 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H16 compound treatment 0.325 -0.00288 -0.11 0.322 -0.00338 -0.07 -0.1299 -0.9744 1435420 IFLab1_000874 COc1ccccc1N2CCN(Cc3c(O)ccc4ccccc34)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H17 compound treatment 0.359 0.0311 1.22 0.361 0.0356 0.75 1.3925 0.9718 2066207 IFLab1_000875 NC1=C(C#N)C(C2CCCCC2)C(=C(N)S1)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H18 compound treatment 0.327 -8.75E-4 -0.03 0.338 0.0126 0.26 0.1625 0.6099 1654724 IFLab1_000876 Cc1cc(nc2ccccc12)n3ncc(C#N)c3N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H19 compound treatment 0.347 0.0191 0.75 0.354 0.0286 0.6 0.9553 0.9937 1276166 IFLab1_000877 Cc1cc(=O)[nH]c(SCC(=O)c2ccc(O)c(O)c2)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H20 compound treatment 0.338 0.0101 0.4 0.329 0.00362 0.08 0.3351 0.827 1459080 IFLab1_000878 CCN(c1ccccc1)S(=O)(=O)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H21 compound treatment 0.336 0.00812 0.32 0.336 0.0106 0.22 0.3831 0.9843 2066208 IFLab1_000879 Cc1nc2cc(ccc2[nH]1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H22 compound treatment 0.322 -0.00588 -0.23 0.335 0.00962 0.2 -0.0209 -0.0682 1472629 IFLab1_000880 O=C(Cc1cccc2ccccc12)N3CCN(Cc4ccccc4)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H23 mock treatment 0.331 0.00312 0.12 0.324 -0.00138 -0.03 0.0665 0.5273 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 H24 positive control 0.083 -0.245 -9.63 0.082 -0.243 -5.09 -10.4093 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I01 compound treatment 0.341 0.0131 0.52 0.322 -0.00338 -0.07 0.315 0.6047 2066209 IFLab1_000881 Cc1ccc(/C=C\2/SC(=S)N(CCC(=O)N3CCOCC3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I02 compound treatment 0.342 0.0141 0.56 0.351 0.0256 0.54 0.7719 0.9998 1634133 IFLab1_000882 Nc1nc(c(s1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I03 compound treatment 0.342 0.0141 0.56 0.344 0.0186 0.39 0.6683 0.985 1438750 IFLab1_000883 CC(C)CNC(=O)COc1ccc2ccccc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I04 compound treatment 0.33 0.00212 0.08 0.339 0.0136 0.29 0.2607 0.8774 1154208 IFLab1_000884 O=C1CCCN1c2sc3CCCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I05 compound treatment 0.359 0.0311 1.22 0.353 0.0276 0.58 1.2741 0.9414 1095704 IFLab1_000885 O=C(CSc1nc(c(o1)c2ccccc2)c3ccccc3)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I06 compound treatment 0.345 0.0171 0.67 0.342 0.0166 0.35 0.7221 0.9528 1564129 IFLab1_000886 COc1ccc2c(C)cc(SCC#N)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I07 compound treatment 0.345 0.0171 0.67 0.342 0.0166 0.35 0.7221 0.9528 2066210 IFLab1_000887 COc1ccc(cc1)C(=O)CSc2ncccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I08 compound treatment 0.341 0.0131 0.52 0.348 0.0226 0.47 0.6997 0.9991 1008544 IFLab1_000888 COc1ccc(CC#N)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I09 compound treatment 0.343 0.0151 0.59 0.349 0.0236 0.49 0.7701 0.9958 2066211 IFLab1_000889 O=C(OCc1nc2ccccc2s1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I10 compound treatment 0.358 0.0301 1.18 0.347 0.0216 0.45 1.1575 0.9129 1592383 IFLab1_000890 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CSc2nnnn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I11 compound treatment 0.328 1.25E-4 0.0 0.352 0.0266 0.56 0.3974 0.7133 1326458 IFLab1_000891 OC(=O)CCC(=O)Nc1cccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I12 compound treatment 0.339 0.0111 0.44 0.338 0.0126 0.26 0.4961 0.9708 1047487 IFLab1_000892 Cc1ccc(cc1)S(=O)(=O)N2C=Cc3ccccc3C2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I13 compound treatment 0.351 0.0231 0.91 0.332 0.00662 0.14 0.741 0.8056 2066212 IFLab1_000893 O=C(OC/C=C/c1ccccc1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I14 compound treatment 0.34 0.0121 0.48 0.326 6.25E-4 0.01 0.3463 0.7262 2066213 IFLab1_000894 Cc1ccc(cc1)C(=O)Cn2cncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I15 compound treatment 0.337 0.00912 0.36 0.338 0.0126 0.26 0.4405 0.9887 1310409 IFLab1_000895 Clc1ccc(cc1)C(=O)c2cnc3CCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I16 compound treatment 0.336 0.00812 0.32 0.34 0.0146 0.31 0.4423 0.9998 1529319 IFLab1_000896 COC(=O)c1cccc(n1)C(=O)Nc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I17 compound treatment 0.324 -0.00388 -0.15 0.339 0.0136 0.29 0.0939 0.2904 1244491 IFLab1_000897 CC(CO)NCC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I18 compound treatment 0.339 0.0111 0.44 0.346 0.0206 0.43 0.6145 1.0 1550073 IFLab1_000898 CN(C)CCOC(=O)C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I19 compound treatment 0.338 0.0101 0.4 0.344 0.0186 0.39 0.5571 0.9999 1254871 IFLab1_000899 CCc1nnc2c3cnn(c4ccccc4)c3ncn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I20 compound treatment 0.328 1.25E-4 0.0 0.327 0.00162 0.03 0.0275 0.801 1686352 IFLab1_000900 CC1CCN(CC1)C(=O)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I21 compound treatment 0.345 0.0171 0.67 0.339 0.0136 0.29 0.6777 0.9269 1324070 IFLab1_000901 C1CN(CCO1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I22 compound treatment 0.339 0.0111 0.44 0.341 0.0156 0.33 0.5405 0.9897 2066214 IFLab1_000902 Brc1ccc(o1)C(=O)Oc2ccc(C#N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I23 mock treatment 0.333 0.00512 0.2 0.329 0.00362 0.08 0.1961 0.9109 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 I24 positive control 0.084 -0.244 -9.59 0.082 -0.243 -5.09 -10.3815 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J01 compound treatment 0.332 0.00412 0.16 0.324 -0.00138 -0.03 0.0943 0.5727 1589564 IFLab1_000903 COc1ccc(Cl)cc1S(=O)(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J02 compound treatment 0.328 1.25E-4 0.0 0.328 0.00262 0.05 0.0423 0.7673 2066215 IFLab1_000904 ClC(=Cc1nc2ccccc2s1)Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J03 compound treatment 0.345 0.0171 0.67 0.354 0.0286 0.6 0.8997 0.9983 1255108 IFLab1_000905 CCOc1ccc(c2ccccc12)S(=O)(=O)NCc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J04 compound treatment 0.34 0.0121 0.48 0.336 0.0106 0.22 0.4943 0.9397 1662205 IFLab1_000906 CC(C)(C)C(=O)Nc1ccc(O)c(c1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J05 compound treatment 0.324 -0.00388 -0.15 0.323 -0.00238 -0.05 -0.1429 -0.8915 1538879 IFLab1_000907 COc1cccc(OC)c1C(=O)Nc2ccc(Br)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J06 compound treatment 0.326 -0.00188 -0.07 0.333 0.00762 0.16 0.0607 0.3453 1596098 IFLab1_000908 Clc1ccc(cc1)c2csc(NCC=C)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J07 compound treatment 0.331 0.00312 0.12 0.335 0.00962 0.2 0.2293 0.9719 2066216 IFLab1_000909 Cc1ccsc1/C=N/c2ccc(Cl)cn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J08 compound treatment 0.326 -0.00188 -0.07 0.331 0.00562 0.12 0.0311 0.224 1702801 IFLab1_000910 CC(C)C(=O)Nc1ccc(Cl)c(c1)C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J09 compound treatment 0.305 -0.0229 -0.9 0.304 -0.0214 -0.45 -0.9523 -0.948 2066217 IFLab1_000911 CC1=C(C)CS(=O)N(C1)C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J10 compound treatment 0.334 0.00612 0.24 0.337 0.0116 0.24 0.3423 1.0 1864905 IFLab1_000912 OC(=O)c1cccc(NS(=O)(=O)/C=C/c2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J11 compound treatment 0.338 0.0101 0.4 0.346 0.0206 0.43 0.5867 0.9992 2066218 IFLab1_000913 Clc1ccc(SCn2c(=S)sc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J12 compound treatment 0.343 0.0151 0.59 0.345 0.0196 0.41 0.7109 0.9837 2066219 IFLab1_000914 OC(=O)/C=C/c1cccc(NS(=O)(=O)c2cccc3cccnc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J13 compound treatment 0.322 -0.00588 -0.23 0.325 -3.75E-4 -0.01 -0.1689 -0.7307 1715445 IFLab1_000915 Nc1nc(cs1)c2ccc(NC(=O)c3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J14 compound treatment 0.341 0.0131 0.52 0.341 0.0156 0.33 0.5961 0.9758 1467660 IFLab1_000916 OC(=O)C1CCCCN1S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J15 compound treatment 0.342 0.0141 0.56 0.327 0.00162 0.03 0.4167 0.749 2066220 IFLab1_000917 Cc1nc(SCC(=O)c2ccc(Cl)cc2)c(C#N)c(C)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J16 compound treatment 0.343 0.0151 0.59 0.337 0.0116 0.24 0.5925 0.9222 2066221 IFLab1_000918 Cc1[nH]nc(c1c2nc3ccccc3s2)c4ccc(O)cc4O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J17 compound treatment 0.335 0.00712 0.28 0.351 0.0256 0.54 0.5773 0.9542 2066222 IFLab1_000919 CCOC(=O)CSc1nc(N)c(C#N)c(CC(C)C)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J18 compound treatment 0.379 0.0511 2.01 0.361 0.0356 0.75 1.9485 0.9089 2066223 IFLab1_000920 Cc1cc(N)n(n1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J19 compound treatment 0.343 0.0151 0.59 0.349 0.0236 0.49 0.7701 0.9958 2066224 IFLab1_000921 CN(Cc1ccccc1)c2cc(C)ncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J20 compound treatment 0.333 0.00512 0.2 0.327 0.00162 0.03 0.1665 0.8149 2066225 IFLab1_000922 O=C(CSc1ncnc2sc3CCCCc3c12)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J21 compound treatment 0.302 -0.0259 -1.02 0.322 -0.00338 -0.07 -0.7693 -0.7544 2066226 IFLab1_000923 Cc1nc2cc(ccc2s1)S(=O)(=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J22 compound treatment 0.336 0.00812 0.32 0.32 -0.00538 -0.11 0.1464 0.4321 2066227 IFLab1_000924 O=C(Cc1cccc2ccccc12)NCCCN3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J23 mock treatment 0.324 -0.00388 -0.15 0.323 -0.00238 -0.05 -0.1429 -0.8915 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 J24 positive control 0.085 -0.243 -9.55 0.083 -0.242 -5.07 -10.3389 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K01 compound treatment 0.353 0.0251 0.99 0.349 0.0236 0.49 1.0481 0.9488 2066228 IFLab1_000925 CCOc1ccc(NC(=O)CN2C(=O)S/C(=C/c3ccc(Cl)cc3)/C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K02 compound treatment 0.33 0.00212 0.08 0.343 0.0176 0.37 0.3199 0.8459 2066229 IFLab1_000926 Clc1cc(c2ccccc2)c3ccccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K03 compound treatment 0.349 0.0211 0.83 0.343 0.0176 0.37 0.8481 0.9332 2066230 IFLab1_000927 Brc1ccc(OCC(=O)Oc2ccc(C#N)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K04 compound treatment 0.358 0.0301 1.18 0.354 0.0286 0.6 1.2611 0.9501 1721773 IFLab1_000928 OC(=O)c1c(NC(=O)c2ccccc2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K05 compound treatment 0.338 0.0101 0.4 0.332 0.00662 0.14 0.3795 0.9003 1153573 IFLab1_000929 O=C(CSc1nc(c(o1)c2ccccc2)c3ccccc3)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K06 compound treatment 0.328 1.25E-4 0.0 0.332 0.00662 0.14 0.1015 0.7317 2066231 IFLab1_000930 CCOC(=O)c1c(NC(=O)c2ccco2)scc1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K07 compound treatment 0.331 0.00312 0.12 0.334 0.00862 0.18 0.2145 0.9824 2066232 IFLab1_000931 O=C(CSc1ncccn1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K08 compound treatment 0.39 0.0621 2.44 0.397 0.0716 1.5 2.787 0.9725 1010920 IFLab1_000932 Nc1ccccc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K09 compound treatment 0.345 0.0171 0.67 0.345 0.0196 0.41 0.7665 0.9719 1618688 IFLab1_000933 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)N=c2sc3cc(C)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K10 compound treatment 0.364 0.0361 1.42 0.364 0.0386 0.81 1.5759 0.9643 1047471 IFLab1_000934 O=C(CS(=O)(=O)CC(=O)c1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K11 compound treatment 0.337 0.00912 0.36 0.343 0.0176 0.37 0.5145 0.9999 1606914 IFLab1_000935 OC(=O)CCC(=O)Nc1ccc(Br)cn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K12 compound treatment 0.332 0.00412 0.16 0.353 0.0276 0.58 0.5235 0.8718 1175259 IFLab1_000936 Clc1ccc(cc1)C(=O)N2CCC(=O)c3cc4ccccc4cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K13 compound treatment 0.34 0.0121 0.48 0.349 0.0236 0.49 0.6867 0.9998 2066233 IFLab1_000937 COc1ccc(/C=C/C(=O)Nc2nc3ccccc3s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K14 compound treatment 0.343 0.0151 0.59 0.348 0.0226 0.47 0.7553 0.9936 1316988 IFLab1_000938 OCc1nc(CO)n(Cc2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K15 compound treatment 0.349 0.0211 0.83 0.351 0.0256 0.54 0.9665 0.9776 2066234 IFLab1_000939 Brc1ccc(cc1)c2cnc3CCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K16 compound treatment 0.358 0.0301 1.18 0.365 0.0396 0.83 1.4239 0.9848 1257868 IFLab1_000940 COC(=O)c1nc(O)c2ccccc2c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K17 compound treatment 0.337 0.00912 0.36 0.347 0.0216 0.45 0.5737 0.9934 1431440 IFLab1_000941 CC1(C)CC(=O)C2=C(C1)Nc3ncnn3C2c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K18 compound treatment 0.335 0.00712 0.28 0.315 -0.0104 -0.22 0.0446 0.1258 1164420 IFLab1_000942 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nc3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K19 compound treatment 0.346 0.0181 0.71 0.347 0.0216 0.45 0.8239 0.976 2066235 IFLab1_000943 O=C(CSc1nnnn1c2ccccc2)Nc3ccc(cc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K20 compound treatment 0.34 0.0121 0.48 0.346 0.0206 0.43 0.6423 0.9988 1254000 IFLab1_000944 CCOc1ccc(cc1)C(=O)NC2CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K21 compound treatment 0.343 0.0151 0.59 0.343 0.0176 0.37 0.6813 0.9736 1563387 IFLab1_000945 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(Cl)cc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K22 compound treatment 0.318 -0.00988 -0.39 0.327 0.00162 0.03 -0.2505 -0.6427 1251633 IFLab1_000946 CC(C)COc1cccc(OCC(=O)Nc2cccc(Cl)c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K23 mock treatment 0.314 -0.0139 -0.55 0.31 -0.0154 -0.32 -0.6133 -0.9683 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 K24 positive control 0.086 -0.242 -9.51 0.085 -0.24 -5.03 -10.2815 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L01 compound treatment 0.345 0.0171 0.67 0.349 0.0236 0.49 0.8257 0.9885 1467605 IFLab1_000947 COc1ccc(Cl)cc1S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L02 compound treatment 0.328 1.25E-4 0.0 0.329 0.00362 0.08 0.0571 0.7513 2066236 IFLab1_000948 Cc1ccc(O)c(c1)C(N)(C(F)(F)F)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L03 compound treatment 0.347 0.0191 0.75 0.342 0.0166 0.35 0.7777 0.9387 2066237 IFLab1_000949 Cc1cn(cn1)S(=O)(=O)c2ccc(Br)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L04 compound treatment 0.352 0.0241 0.95 0.332 0.00662 0.14 0.7688 0.8019 1529937 IFLab1_000950 Oc1ccc(NC(=O)Cc2ccccc2)cc1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L05 compound treatment 0.338 0.0101 0.4 0.33 0.00462 0.1 0.3499 0.8541 1462872 IFLab1_000951 CC(C)c1nccn1C(=O)c2ccccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L06 compound treatment 0.335 0.00712 0.28 0.324 -0.00138 -0.03 0.1777 0.6312 1915820 IFLab1_000952 CC(=O)N=c1scc(c2ccccc2)n1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L07 compound treatment 0.341 0.0131 0.52 0.331 0.00562 0.12 0.4481 0.8467 1702422 IFLab1_000953 COc1ccc(cc1)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L08 compound treatment 0.33 0.00212 0.08 0.334 0.00862 0.18 0.1867 0.9387 1383579 IFLab1_000954 CN(c1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L09 compound treatment 0.333 0.00512 0.2 0.334 0.00862 0.18 0.2701 0.9985 2066238 IFLab1_000955 Clc1ccc(cc1)S(=O)(=O)/C(=C\c2ccccc2)/NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L10 compound treatment 0.359 0.0311 1.22 0.331 0.00562 0.12 0.9486 0.7716 2066239 IFLab1_000956 Cc1cc(C)nc(Nc2ccc(NS(=O)(=O)/C=C/c3ccccc3)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L11 compound treatment 0.327 -8.75E-4 -0.03 0.337 0.0116 0.24 0.1477 0.6011 1261562 IFLab1_000957 CC(=O)NC(Sc1ccc(Cl)cc1)C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L12 compound treatment 0.345 0.0171 0.67 0.34 0.0146 0.31 0.6925 0.9363 2066240 IFLab1_000958 FC(F)(F)c1ccc(nc1)n2cc(ccc2=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L13 compound treatment 0.334 0.00612 0.24 0.336 0.0106 0.22 0.3275 0.9992 2066241 IFLab1_000959 COc1ccc(cc1)n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L14 compound treatment 0.337 0.00912 0.36 0.329 0.00362 0.08 0.3073 0.8381 1119664 IFLab1_000960 CC1CCN(CC1)S(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L15 compound treatment 0.348 0.0201 0.79 0.337 0.0116 0.24 0.7315 0.8837 1498580 IFLab1_000961 COc1ccc(cc1)C(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L16 compound treatment 0.339 0.0111 0.44 0.338 0.0126 0.26 0.4961 0.9708 1197423 IFLab1_000962 O=C(Nc1cc(ncn1)N2CCOCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L17 compound treatment 0.341 0.0131 0.52 0.348 0.0226 0.47 0.6997 0.9991 2066242 IFLab1_000963 CCc1c(C#N)c(N)nc(SCC#N)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L18 compound treatment 0.353 0.0251 0.99 0.347 0.0216 0.45 1.0185 0.9374 1639361 IFLab1_000964 COc1ccc2c(C)cc(SCC(=O)Nc3ccc4OCOc4c3)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L19 compound treatment 0.344 0.0161 0.63 0.347 0.0216 0.45 0.7683 0.9863 1243635 IFLab1_000965 COc1ccc(Nc2cc(C)ncn2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L20 compound treatment 0.357 0.0291 1.15 0.358 0.0326 0.68 1.2925 0.9695 1273163 IFLab1_000966 COc1ccc2c(C)cc(SCC(=O)Nc3ccccc3)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L21 compound treatment 0.343 0.0151 0.59 0.347 0.0216 0.45 0.7405 0.9909 2066243 IFLab1_000967 CC1(C)CC(=O)C(SC(F)(F)F)C(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L22 compound treatment 0.357 0.0291 1.15 0.351 0.0256 0.54 1.1889 0.9402 1259132 IFLab1_000968 Cc1[nH]c2ccccc2c1C(=O)CSc3nnnn3c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L23 mock treatment 0.327 -8.75E-4 -0.03 0.328 0.00262 0.05 0.0145 0.224 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 L24 positive control 0.087 -0.241 -9.47 0.085 -0.24 -5.03 -10.2537 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M01 compound treatment 0.339 0.0111 0.44 0.34 0.0146 0.31 0.5257 0.9847 2066244 IFLab1_000969 Oc1cccc(/C=C/2\SC(=S)N(C2=O)c3ccccc3O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M02 compound treatment 0.346 0.0181 0.71 0.342 0.0166 0.35 0.7499 0.9456 1608089 IFLab1_000970 CC(C)(C)C(=O)Nc1sc2CCCCc2c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M03 compound treatment 0.331 0.00312 0.12 0.334 0.00862 0.18 0.2145 0.9824 1443155 IFLab1_000971 O=C(COc1ccccc1)NC2CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M04 compound treatment 0.334 0.00612 0.24 0.335 0.00962 0.2 0.3127 0.9961 1299013 IFLab1_000972 CCOC(=O)c1c(N)sc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M05 compound treatment 0.323 -0.00488 -0.19 0.31 -0.0154 -0.32 -0.363 -0.9694 1175751 IFLab1_000973 COC(=O)CSc1nc(c(o1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M06 compound treatment 0.326 -0.00188 -0.07 0.331 0.00562 0.12 0.0311 0.224 2066245 IFLab1_000974 OCCSc1ncnc2sc3CCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M07 compound treatment 0.359 0.0311 1.22 0.347 0.0216 0.45 1.1853 0.9085 2066246 IFLab1_000975 Cc1nc2ccccc2nc1SCC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M08 compound treatment 0.34 0.0121 0.48 0.341 0.0156 0.33 0.5683 0.9831 1280132 IFLab1_000976 CN1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M09 compound treatment 0.342 0.0141 0.56 0.337 0.0116 0.24 0.5647 0.9314 1536713 IFLab1_000977 COc1ccc(C(=O)N=c2sc3cc(C)ccc3n2C)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M10 compound treatment 0.467 0.139 5.47 0.347 0.0216 0.45 4.1879 0.763 1587062 IFLab1_000978 CCOC(=O)C1=C(CC)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M11 compound treatment 0.312 -0.0159 -0.62 0.328 0.00262 0.05 -0.4025 -0.6424 1203340 IFLab1_000979 Cc1cc2NC(CC(=O)NCc3ccccc3)C(=O)Nc2cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M12 compound treatment 0.47 0.142 5.59 0.464 0.139 2.9 6.0026 0.9534 1162320 IFLab1_000980 O=C1C(C(=O)c2ccccc12)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M13 compound treatment 0.341 0.0131 0.52 0.361 0.0356 0.75 0.892 0.9839 2066247 IFLab1_000981 O=C(COC(=O)/C=C/c1ccco1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M14 compound treatment 0.345 0.0171 0.67 0.332 0.00662 0.14 0.5741 0.8352 1418088 IFLab1_000982 Cc1ccc(cc1)S(=O)(=O)NCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M15 compound treatment 0.333 0.00512 0.2 0.349 0.0236 0.49 0.4921 0.9217 1431241 IFLab1_000983 OC(=O)CCCC(=O)Nc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M16 compound treatment 0.332 0.00412 0.16 0.323 -0.00238 -0.05 0.0795 0.4689 1159607 IFLab1_000984 O=C(NCC1NCCc2ccccc12)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M17 compound treatment 0.326 -0.00188 -0.07 0.352 0.0266 0.56 0.3418 0.6082 1481431 IFLab1_000985 O=S(=O)(NCC1CCCO1)c2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M18 compound treatment 0.355 0.0271 1.07 0.353 0.0276 0.58 1.1629 0.9586 1165794 IFLab1_000986 Nc1nc(cs1)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M19 compound treatment 0.3 -0.0279 -1.1 0.286 -0.0394 -0.82 -1.3576 -0.9901 1391031 IFLab1_000987 Oc1cc(CN2CCCCCC2)c(O)cc1CN3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M20 compound treatment 0.342 0.0141 0.56 0.336 0.0106 0.22 0.5499 0.9193 2066248 IFLab1_000988 FC(F)(F)c1ccccc1N2C(=O)C3C4OC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M21 compound treatment 0.342 0.0141 0.56 0.333 0.00762 0.16 0.5055 0.8749 1918943 IFLab1_000989 OC(=O)CSc1ncnc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M22 compound treatment 0.352 0.0241 0.95 0.332 0.00662 0.14 0.7688 0.8019 1720082 IFLab1_000990 COc1cccc(OCC(=O)OC2CCS(=O)(=O)C2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M23 mock treatment 0.332 0.00412 0.16 0.323 -0.00238 -0.05 0.0795 0.4689 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 M24 positive control 0.09 -0.238 -9.35 0.087 -0.238 -4.99 -10.1407 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N01 compound treatment 0.33 0.00212 0.08 0.332 0.00662 0.14 0.1571 0.9706 1402173 IFLab1_000991 CCOc1ccc(OCC)c(c1)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N02 compound treatment 0.338 0.0101 0.4 0.338 0.0126 0.26 0.4683 0.9802 2066249 IFLab1_000992 Cc1sc[n+](Cc2ccccc2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N03 compound treatment 0.328 1.25E-4 0.0 0.326 6.25E-4 0.01 0.0127 0.9106 2066250 IFLab1_000993 Cc1ccc(cc1C)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N04 compound treatment 0.347 0.0191 0.75 0.332 0.00662 0.14 0.6297 0.8236 1385003 IFLab1_000994 CC(C)C(=O)Nc1ccc(C)cc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N05 compound treatment 0.343 0.0151 0.59 0.337 0.0116 0.24 0.5925 0.9222 1618967 IFLab1_000995 COc1ccc(OC)c(c1)S(=O)(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N06 compound treatment 0.376 0.0481 1.89 0.367 0.0416 0.87 1.9539 0.938 1447645 IFLab1_000996 COc1ccccc1Nc2nc(C)cs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N07 compound treatment 0.355 0.0271 1.07 0.333 0.00762 0.16 0.867 0.804 1265647 IFLab1_000997 COc1cccc(OC)c1C(=O)Nc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N08 compound treatment 0.325 -0.00288 -0.11 0.321 -0.00438 -0.09 -0.1447 -0.9945 1347203 IFLab1_000998 CCOC(=O)COc1nc(nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N09 compound treatment 0.344 0.0161 0.63 0.334 0.00862 0.18 0.5759 0.8737 2066251 IFLab1_000999 OP(=O)(/C(=C\c1ccccc1)/NC(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N10 compound treatment 0.343 0.0151 0.59 0.346 0.0206 0.43 0.7257 0.9876 1783522 IFLab1_001000 O=S(=O)(NC1CCS(=O)(=O)C1)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N11 compound treatment 0.395 0.0671 2.64 0.382 0.0566 1.18 2.7041 0.9347 1478277 IFLab1_001001 Nc1sc2CCCCc2c1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N12 compound treatment 0.362 0.0341 1.34 0.312 -0.0134 -0.28 0.7508 0.5478 1140164 IFLab1_001002 CC1CCCN(C1)C(=O)C2CCN(CC2)S(=O)(=O)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N13 compound treatment 0.336 0.00812 0.32 0.355 0.0296 0.62 0.6643 0.9525 1441266 IFLab1_001003 OC(=O)c1ccccc1C(=O)Nc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N14 compound treatment 0.351 0.0231 0.91 0.355 0.0296 0.62 1.0813 0.9826 1561953 IFLab1_001004 CC1CCCN(C1)S(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N15 compound treatment 0.322 -0.00588 -0.23 0.327 0.00162 0.03 -0.1393 -0.5966 1511809 IFLab1_001005 CCOC(=O)C1=C(C)NC(=C(C#N)C1CC(C)C)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N16 compound treatment 0.346 0.0181 0.71 0.341 0.0156 0.33 0.7351 0.9376 2066252 IFLab1_001006 Oc1nc(nc2ccccc12)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N17 compound treatment 0.381 0.0531 2.09 0.372 0.0466 0.98 2.1669 0.9399 2066253 IFLab1_001007 Nc1nc(SCC#N)c(C#N)c(c2cccs2)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N18 compound treatment 0.358 0.0301 1.18 0.35 0.0246 0.52 1.2019 0.9305 2066254 IFLab1_001008 Nc1c(C#N)cnn1c2ccc(cn2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N19 compound treatment 0.34 0.0121 0.48 0.346 0.0206 0.43 0.6423 0.9988 1146626 IFLab1_001009 Cc1cc(NCc2ccco2)ncn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N20 compound treatment 0.348 0.0201 0.79 0.361 0.0356 0.75 1.0867 0.9996 2066255 IFLab1_001010 Cc1nc(SCCO)c2c3CCCCc3sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N21 compound treatment 0.352 0.0241 0.95 0.346 0.0206 0.43 0.9759 0.9365 2066256 IFLab1_001011 OC(=O)c1c(F)c(F)c(F)c(F)c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N22 compound treatment 0.348 0.0201 0.79 0.35 0.0246 0.52 0.9239 0.9784 1668611 IFLab1_001012 Cc1[nH]c2ccccc2c1c3csc(N)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N23 mock treatment 0.332 0.00412 0.16 0.33 0.00462 0.1 0.1831 0.9696 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 N24 positive control 0.09 -0.238 -9.35 0.088 -0.237 -4.97 -10.1259 -0.9562 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O01 compound treatment 0.492 0.164 6.45 0.499 0.174 3.63 7.1322 0.9631 2066257 IFLab1_001013 CCCC(N1C(=O)/C(=C/c2ccc(O)c(OCC)c2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O02 compound treatment 0.338 0.0101 0.4 0.34 0.0146 0.31 0.4979 0.9916 1703333 IFLab1_001014 CC(C)(C)c1nc2sc3CCCCc3c2c(=O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O03 compound treatment 0.332 0.00412 0.16 0.323 -0.00238 -0.05 0.0795 0.4689 1529241 IFLab1_001015 CC(NC(=O)C1(CC2CC3CC(C2)C1)C3)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O04 compound treatment 0.348 0.0201 0.79 0.346 0.0206 0.43 0.8647 0.9594 1618285 IFLab1_001016 COc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2CN(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O05 compound treatment 0.335 0.00712 0.28 0.344 0.0186 0.39 0.4737 0.9869 2066258 IFLab1_001017 Oc1nc(c2ccccc2)c3ccccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O06 compound treatment 0.337 0.00912 0.36 0.336 0.0106 0.22 0.4109 0.9735 2066259 IFLab1_001018 CCc1nc2sccc2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O07 compound treatment 0.339 0.0111 0.44 0.338 0.0126 0.26 0.4961 0.9708 1582358 IFLab1_001019 O=C(CSc1nncc2ccccc12)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O08 compound treatment 0.353 0.0251 0.99 0.357 0.0316 0.66 1.1665 0.981 2066260 IFLab1_001020 NNc1nc(c2ccccc2)c3ccccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O09 compound treatment 0.335 0.00712 0.28 0.334 0.00862 0.18 0.3257 0.9774 2066261 IFLab1_001021 Cc1ccc2n(C)c(=NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O10 compound treatment 0.347 0.0191 0.75 0.324 -0.00138 -0.03 0.5114 0.6796 1101412 IFLab1_001022 CC1C(NC(C(C)C1=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O11 compound treatment 0.347 0.0191 0.75 0.334 0.00862 0.18 0.6593 0.8526 1408775 IFLab1_001023 COc1ccc(NC2CC(=O)N(Cc3ccccc3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O12 compound treatment 0.353 0.0251 0.99 0.355 0.0296 0.62 1.1369 0.9748 1155862 IFLab1_001024 OC(=O)c1ccc(C(=O)O)c(c1)C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O13 compound treatment 0.353 0.0251 0.99 0.362 0.0366 0.77 1.2405 0.9921 1565787 IFLab1_001025 O=c1oc2cc(OCc3ccccc3)ccc2cc1c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O14 compound treatment 0.349 0.0211 0.83 0.35 0.0246 0.52 0.9517 0.9736 1547967 IFLab1_001026 CN(C)CCOC(=O)C1(CC2CC3C1)CC(C2)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O15 compound treatment 0.35 0.0221 0.87 0.347 0.0216 0.45 0.9351 0.9536 2066262 IFLab1_001027 N(=c1[nH]c(cs1)c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O16 compound treatment 0.346 0.0181 0.71 0.348 0.0226 0.47 0.8387 0.9803 2066263 IFLab1_001028 Nc1ccc(cc1)C(=O)OCCCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O17 compound treatment 0.345 0.0171 0.67 0.346 0.0206 0.43 0.7813 0.9769 2066264 IFLab1_001029 CCOC(=O)c1c(NC(=O)/C=C/c2ccc(OC)cc2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O18 compound treatment 0.34 0.0121 0.48 0.34 0.0146 0.31 0.5535 0.977 1577258 IFLab1_001030 COc1cc2CC(C)(C)n3c(C)nnc3-c2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O19 compound treatment 0.338 0.0101 0.4 0.345 0.0196 0.41 0.5719 0.9999 1536183 IFLab1_001031 Nc1nc(c(CC(=O)O)s1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O20 compound treatment 0.339 0.0111 0.44 0.328 0.00262 0.05 0.3481 0.7897 1438322 IFLab1_001032 CN(C)c1ccc(NC(=O)CC2Sc3ccccc3NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O21 compound treatment 0.352 0.0241 0.95 0.355 0.0296 0.62 1.1091 0.9788 1194533 IFLab1_001033 CCOC(=O)c1c(C)[nH]c(C(=O)CC#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O22 compound treatment 0.324 -0.00388 -0.15 0.327 0.00162 0.03 -0.0837 -0.5361 1527606 IFLab1_001034 COc1ccc(NC(=O)COc2cccc(OCC(C)C)c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O23 mock treatment 0.326 -0.00188 -0.07 0.33 0.00462 0.1 0.0163 0.134 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 O24 positive control 0.093 -0.235 -9.23 0.09 -0.235 -4.93 -10.0129 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P01 compound treatment 0.343 0.0151 0.59 0.337 0.0116 0.24 0.5925 0.9222 1256291 IFLab1_001035 CCOc1ccc(OCC)c(c1)S(=O)(=O)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P02 compound treatment 0.343 0.0151 0.59 0.341 0.0156 0.33 0.6517 0.9603 1131746 IFLab1_001036 Cc1ncc(CN2CCCCC2)c(N)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P03 compound treatment 0.34 0.0121 0.48 0.336 0.0106 0.22 0.4943 0.9397 2066265 IFLab1_001037 CCC1CCCCN1S(=O)(=O)c2c(C)cc(C)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P04 compound treatment 0.362 0.0341 1.34 0.366 0.0406 0.85 1.5499 0.9758 1316159 IFLab1_001038 Cc1ccc(NC(=O)c2ccco2)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P05 compound treatment 0.377 0.0491 1.93 0.385 0.0596 1.25 2.2481 0.9776 1726579 IFLab1_001039 O=C(NCc1cccnc1)c2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P06 compound treatment 0.406 0.0781 3.07 0.394 0.0686 1.44 3.1875 0.94 1142713 IFLab1_001040 COC(=O)Cc1csc(N)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P07 compound treatment 0.376 0.0481 1.89 0.375 0.0496 1.04 2.0723 0.9601 1493096 IFLab1_001041 Brc1ccc(cc1)C(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P08 compound treatment 0.376 0.0481 1.89 0.395 0.0696 1.46 2.3682 0.9917 2066266 IFLab1_001042 Oc1nc(c2ccc(Cl)cc2)c3ccccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P09 compound treatment 0.388 0.0601 2.36 0.376 0.0506 1.06 2.4207 0.9344 1448916 IFLab1_001043 CC(=O)Nc1sc(nc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P10 compound treatment 0.407 0.0791 3.11 0.411 0.0856 1.79 3.4668 0.9657 2066267 IFLab1_001044 OCCSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P11 compound treatment 0.362 0.0341 1.34 0.373 0.0476 1.0 1.6535 0.9893 1306282 IFLab1_001045 CC(C)c1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P12 compound treatment 0.401 0.0731 2.88 0.382 0.0566 1.18 2.8709 0.9232 1448828 IFLab1_001046 O=C(Nc1cccc2ccccc12)C3CCCCN3S(=O)(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P13 compound treatment 0.382 0.0541 2.13 0.397 0.0716 1.5 2.5646 0.9853 1630696 IFLab1_001047 COc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P14 compound treatment 0.381 0.0531 2.09 0.351 0.0256 0.54 1.8562 0.8607 2066268 IFLab1_001048 OC(=O)/C=C/C(=O)N1CCCC(C1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P15 compound treatment 0.383 0.0551 2.17 0.401 0.0756 1.58 2.6516 0.9881 2066269 IFLab1_001049 CCc1ccc(cc1)C2C(=C(N)SC(=C2C#N)N)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P16 compound treatment 0.374 0.0461 1.81 0.358 0.0326 0.68 1.7651 0.9109 2066270 IFLab1_001050 CSc1ncnc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P17 compound treatment 0.375 0.0471 1.85 0.373 0.0476 1.0 2.0149 0.9577 2066271 IFLab1_001051 CCCOC(=O)CSc1nc(C)cc(C)c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P18 compound treatment 0.353 0.0251 0.99 0.362 0.0366 0.77 1.2405 0.9921 2066272 IFLab1_001052 O=C(CSc1nc2scc(c3ccccc3)c2c(=O)[nH]1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P19 compound treatment 0.37 0.0421 1.66 0.365 0.0396 0.83 1.7575 0.9488 2066273 IFLab1_001053 CC(=O)N(/C=C/1\SC(=S)N(CC(F)(F)F)C1=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P20 compound treatment 0.354 0.0261 1.03 0.346 0.0206 0.43 1.0315 0.9258 2066274 IFLab1_001054 COc1ccc(NC(=O)CSc2nnc3ccccn23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P21 compound treatment 0.354 0.0261 1.03 0.347 0.0216 0.45 1.0463 0.9322 2066275 IFLab1_001055 CCn1c(C)nc2cc(NC(=O)C(F)(F)F)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P22 compound treatment 0.348 0.0201 0.79 0.351 0.0256 0.54 0.9387 0.982 2066276 IFLab1_001056 Cc1nc(SCCC(=O)O)c2c3CCCCc3sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P23 mock treatment 0.346 0.0181 0.71 0.339 0.0136 0.29 0.7055 0.9192 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1414 P24 positive control 0.097 -0.231 -9.08 0.093 -0.232 -4.86 -9.8573 -0.9572 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A01 compound treatment 0.348 0.0205 0.81 0.348 0.0202 0.42 0.8687 0.9546 1468351 IFLab1_001057 C1CCc2c(C1)sc3ncnc(Oc4cccnc4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A02 compound treatment 0.321 -0.0065 -0.26 0.339 0.0112 0.23 -0.0152 -0.0438 2066277 IFLab1_001058 Oc1c(/C=N/c2cccnc2)c(=O)oc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A03 compound treatment 0.322 -0.0055 -0.22 0.311 -0.0168 -0.35 -0.4017 -0.9727 1405888 IFLab1_001059 CCOC(=O)c1c(NC(=O)C(C)(C)C)scc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A04 compound treatment 0.328 5.0E-4 0.02 0.331 0.00319 0.07 0.0611 0.8782 1349352 IFLab1_001060 CC1CCc2sc(NC(=O)Cc3ccccc3)c(C(=O)N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A05 compound treatment 0.344 0.0165 0.65 0.314 -0.0138 -0.29 0.2543 0.3581 2066278 IFLab1_001061 S=c1[nH]cnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A06 compound treatment 0.328 5.0E-4 0.02 0.322 -0.00581 -0.12 -0.0721 -0.5852 1150492 IFLab1_001062 CCSc1nnc(NC(=O)C2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A07 compound treatment 0.327 -5.0E-4 -0.02 0.34 0.0122 0.26 0.1664 0.6507 1504404 IFLab1_001063 CCOC(=O)c1c(oc2ccc(O)c(CN(C)C)c12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A08 compound treatment 0.345 0.0175 0.69 0.336 0.00819 0.17 0.6077 0.857 1715117 IFLab1_001064 COc1cc(OC)cc(c1)C(=O)Nc2nnc(s2)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A09 compound treatment 0.327 -5.0E-4 -0.02 0.315 -0.0128 -0.27 -0.2035 -0.7569 1584865 IFLab1_001065 CCOC(=O)c1c(oc2ccc(O)c(CN3CCN(C)CC3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A10 compound treatment 0.327 -5.0E-4 -0.02 0.328 1.88E-4 0.0 -0.0111 -0.555 2066279 IFLab1_001066 Clc1ccc(cc1)c2nnc(NC(=O)/C=C\c3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A11 compound treatment 0.332 0.0045 0.18 0.335 0.00719 0.15 0.2315 0.9967 1279363 IFLab1_001067 CCOC(=O)COc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A12 compound treatment 0.332 0.0045 0.18 0.351 0.0232 0.49 0.4682 0.9066 1250002 IFLab1_001068 COC(=O)C1=C(CCS1)NC(=O)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A13 compound treatment 0.662 0.335 13.15 0.676 0.348 7.29 14.4519 0.9612 1693583 IFLab1_001069 Cc1csc(n1)c2cc3ccc(O)c(CN4CCCC4)c3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A14 compound treatment 0.334 0.0065 0.26 0.33 0.00219 0.05 0.2131 0.8207 1436211 IFLab1_001070 COC(=O)C1=C(CCS1)NC(=O)COc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A15 compound treatment 0.33 0.0025 0.1 0.313 -0.0148 -0.31 -0.1497 -0.4603 1139829 IFLab1_001071 COc1cccc(OCC(=O)N(C)C2CCS(=O)(=O)C2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A16 compound treatment 0.33 0.0025 0.1 0.334 0.00619 0.13 0.1611 0.9908 1559224 IFLab1_001072 Cc1ccc(cc1)c2nnc(NC(=O)COc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A17 compound treatment 0.344 0.0165 0.65 0.314 -0.0138 -0.29 0.2543 0.3581 1218799 IFLab1_001073 O=C(Nc1sc2CCCc2c1C#N)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A18 compound treatment 0.326 -0.0015 -0.06 0.33 0.00219 0.05 -0.0093 -0.125 1248136 IFLab1_001074 CC1(C)CC(=O)c2sc(NC(=O)C3CCCCC3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A19 compound treatment 0.332 0.0045 0.18 0.361 0.0332 0.69 0.6162 0.8598 1169304 IFLab1_001075 O=C(Nc1ccccc1c2nc3ccccc3[nH]2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A20 compound treatment 0.326 -0.0015 -0.06 0.324 -0.00381 -0.08 -0.0981 -0.9889 1732906 IFLab1_001076 Cc1nc2ccc(NC(=O)c3ccc(cc3)N4C(=O)CCC4=O)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A21 compound treatment 0.341 0.0135 0.53 0.324 -0.00381 -0.08 0.3189 0.5942 1461536 IFLab1_001077 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A22 compound treatment 0.322 -0.0055 -0.22 0.323 -0.00481 -0.1 -0.2241 -0.9395 2066280 IFLab1_001078 CC(C)(C)Nc1scc(c2ccccc2)[n+]1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A23 mock treatment 0.321 -0.0065 -0.26 0.344 0.0162 0.34 0.0588 0.1386 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 A24 positive control 0.078 -0.25 -9.81 0.078 -0.25 -5.23 -10.6331 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B01 compound treatment 0.338 0.0105 0.41 0.336 0.00819 0.17 0.4131 0.9241 1359222 IFLab1_001079 Cc1nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B02 compound treatment 0.328 5.0E-4 0.02 0.335 0.00719 0.15 0.1203 0.7928 1724523 IFLab1_001080 Nc1ccc(cc1N)C(=O)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B03 compound treatment 0.331 0.0035 0.14 0.329 0.00119 0.02 0.1149 0.8215 1187088 IFLab1_001081 Clc1ccc(cc1)c2csc(NC(=O)COc3ccccc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B04 compound treatment 0.341 0.0135 0.53 0.336 0.00819 0.17 0.4965 0.8901 1137914 IFLab1_001082 COc1ccc(Nc2ccnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B05 compound treatment 0.33 0.0025 0.1 0.319 -0.00881 -0.18 -0.0609 -0.2914 2066281 IFLab1_001083 CCCC(=O)Nc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B06 compound treatment 0.324 -0.0035 -0.14 0.337 0.00919 0.19 0.0386 0.1634 1210687 IFLab1_001084 Cc1ccnc(NC(=O)C2CCCCC2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B07 compound treatment 0.34 0.0125 0.49 0.336 0.00819 0.17 0.4687 0.9005 1334135 IFLab1_001085 O=C(NCc1ccccc1)c2cc3c(ccc4ccccc43)oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B08 compound treatment 0.342 0.0145 0.57 0.335 0.00719 0.15 0.5095 0.8641 1983536 IFLab1_001086 CCOC(=O)C(N)CSC1CCCCO1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B09 compound treatment 0.363 0.0355 1.4 0.373 0.0452 0.95 1.6556 0.982 2066282 IFLab1_001087 COc1ccc(/N=C/2\NC(=O)C(Cc3ccc(C)cc3)S2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B10 compound treatment 0.222 -0.106 -4.15 0.222 -0.106 -2.21 -4.4988 -0.9568 2066283 IFLab1_001088 [O-][n+]1onc(C(=O)c2cccs2)c1C(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B11 compound treatment 0.345 0.0175 0.69 0.338 0.0102 0.21 0.6373 0.8847 1403758 IFLab1_001089 O=C(COc1ccccc1)Nc2ncc(Cc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B12 compound treatment 0.34 0.0125 0.49 0.341 0.0132 0.28 0.5427 0.9628 1603086 IFLab1_001090 OC(=O)C(NC(=O)c1ccccc1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B13 compound treatment 0.324 -0.0035 -0.14 0.323 -0.00481 -0.1 -0.1685 -0.9882 1520010 IFLab1_001091 O=S(=O)(CCOc1ccccc1)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B14 compound treatment 0.326 -0.0015 -0.06 0.342 0.0142 0.3 0.1682 0.5558 2066284 IFLab1_001092 C(Sc1nncn1c2ccccc2)c3cn4ccsc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B15 compound treatment 0.32 -0.0075 -0.29 0.332 0.00419 0.09 -0.1466 -0.4764 2066285 IFLab1_001093 CC(C)(C)c1ccc(/C=C/C(=O)O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B16 compound treatment 0.338 0.0105 0.41 0.325 -0.00281 -0.06 0.2503 0.6002 1656781 IFLab1_001094 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)C(=O)c4ccccc4)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B17 compound treatment 0.339 0.0115 0.45 0.335 0.00719 0.15 0.4261 0.8941 2066286 IFLab1_001095 COC(=O)CCS(=O)(=O)c1ccc(Cl)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B18 compound treatment 0.338 0.0105 0.41 0.34 0.0122 0.26 0.4723 0.9732 1179259 IFLab1_001096 Clc1ccc(Cl)c(Cc2cnc(NC(=O)C3CCCO3)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B19 compound treatment 0.342 0.0145 0.57 0.338 0.0102 0.21 0.5539 0.91 1224001 IFLab1_001097 CCN1CCN(CC1)c2cc3N(C)c4ccccc4Oc3nn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B20 compound treatment 0.333 0.0055 0.22 0.34 0.0122 0.26 0.3333 0.9966 1349850 IFLab1_001098 COc1ccc(cc1)c2csc(N)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B21 compound treatment 0.336 0.0085 0.33 0.34 0.0122 0.26 0.4167 0.9911 1917751 IFLab1_001099 COC(=O)CCC(=O)c1ccc(Br)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B22 compound treatment 0.336 0.0085 0.33 0.334 0.00619 0.13 0.3279 0.9148 1140317 IFLab1_001100 CC(=O)Nc1ccc(cc1)c2cn3ccsc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B23 mock treatment 0.329 0.0015 0.06 0.33 0.00219 0.05 0.0741 0.9922 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 B24 positive control 0.081 -0.247 -9.69 0.078 -0.25 -5.23 -10.5497 -0.958 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C01 compound treatment 0.34 0.0125 0.49 0.336 0.00819 0.17 0.4687 0.9005 1223908 IFLab1_001101 Nc1nc(cs1)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C02 compound treatment 0.334 0.0065 0.26 0.336 0.00819 0.17 0.3019 0.9811 1149446 IFLab1_001102 Clc1ccc(cc1)C2=C(C#N)C(=O)Nc3ccccc3S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C03 compound treatment 0.34 0.0125 0.49 0.332 0.00419 0.09 0.4095 0.8202 1273996 IFLab1_001103 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C04 compound treatment 0.345 0.0175 0.69 0.337 0.00919 0.19 0.6225 0.8713 1668048 IFLab1_001104 COc1ccc(cc1OC)C(=O)Nc2sc3CCC(C)Cc3c2C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C05 compound treatment 0.322 -0.0055 -0.22 0.335 0.00719 0.15 -0.0466 -0.1767 1663578 IFLab1_001105 CN1CCCN(CC1)c2nc(C)nc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C06 compound treatment 0.34 0.0125 0.49 0.341 0.0132 0.28 0.5427 0.9628 1541981 IFLab1_001106 CCSc1nnc(NC(=O)c2ccc(cc2)c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C07 compound treatment 0.365 0.0375 1.47 0.364 0.0362 0.76 1.578 0.9521 1728326 IFLab1_001107 COc1ccc2oc(c(C(=O)N)c2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C08 compound treatment 0.343 0.0155 0.61 0.342 0.0142 0.3 0.6409 0.9454 1403107 IFLab1_001108 COc1ccccc1C(=O)Nc2nnc(s2)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C09 compound treatment 0.308 -0.0195 -0.77 0.314 -0.0138 -0.29 -0.7465 -0.9111 1458750 IFLab1_001109 CC(C)OC(=O)c1c(C)oc2ccc(OC(=O)C(C)C)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C10 compound treatment 0.338 0.0105 0.41 0.345 0.0172 0.36 0.5462 0.9976 1170894 IFLab1_001110 COC(=O)C1=C(CCS1)NC(=O)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C11 compound treatment 0.361 0.0335 1.32 0.357 0.0292 0.61 1.3633 0.939 1702141 IFLab1_001111 CCc1cc(C(=O)Cn2cnc3ccccc23)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C12 compound treatment 0.335 0.0075 0.29 0.329 0.00119 0.02 0.2261 0.764 1529753 IFLab1_001112 CCc1nnc(NC(=O)c2cc3ccccc3cc2OC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C13 compound treatment 0.34 0.0125 0.49 0.331 0.00319 0.07 0.3947 0.7958 2066287 IFLab1_001113 COC(=O)NC1(Oc2cc(Cl)c(Cl)cc2O1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C14 compound treatment 0.355 0.0275 1.08 0.352 0.0242 0.51 1.1225 0.9402 1223344 IFLab1_001114 COC(=O)C1=C(CCS1)NC(=O)c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C15 compound treatment 0.333 0.0055 0.22 0.335 0.00719 0.15 0.2593 0.9843 1602437 IFLab1_001115 COc1cccc(OCC(=O)NCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C16 compound treatment 0.341 0.0135 0.53 0.337 0.00919 0.19 0.5113 0.9057 1667248 IFLab1_001116 Fc1ccc(cc1)c2nnc(NC(=O)COc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C17 compound treatment 0.328 5.0E-4 0.02 0.337 0.00919 0.19 0.1498 0.7754 2066288 IFLab1_001117 Brc1ccc(s1)C(=O)NCC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C18 compound treatment 0.343 0.0155 0.61 0.326 -0.00181 -0.04 0.4041 0.6618 2066289 IFLab1_001118 Cn1c(=NC(=O)C2CCCCC2)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C19 compound treatment 0.337 0.0095 0.37 0.334 0.00619 0.13 0.3557 0.8997 1119499 IFLab1_001119 Brc1ccc(NC(=O)C2CC2)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C20 compound treatment 0.364 0.0365 1.44 0.348 0.0202 0.42 1.3135 0.878 1148237 IFLab1_001120 Fc1ccc(cc1)c2csc(NC(=O)c3ccc(cc3)N4C(=O)CCC4=O)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C21 compound treatment 0.354 0.0265 1.04 0.358 0.0302 0.63 1.1834 0.9713 1505492 IFLab1_001121 CCOCN1C(=O)c2cccc3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C22 compound treatment 0.375 0.0475 1.87 0.377 0.0492 1.03 2.0484 0.9606 2066290 IFLab1_001122 COc1ccc(cc1)c2csc(Nc3ccccc3)[n+]2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C23 mock treatment 0.323 -0.0045 -0.18 0.325 -0.00281 -0.06 -0.1667 -0.8941 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 C24 positive control 0.079 -0.249 -9.77 0.078 -0.25 -5.23 -10.6053 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D01 compound treatment 0.344 0.0165 0.65 0.345 0.0172 0.36 0.7131 0.9613 1171021 IFLab1_001123 CCOC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2)nc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D02 compound treatment 0.338 0.0105 0.41 0.325 -0.00281 -0.06 0.2503 0.6002 1127343 IFLab1_001124 CC1(CC2(C)CC3(CC(=O)O)C1)CC(CC(=O)O)(C2)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D03 compound treatment 0.361 0.0335 1.32 0.362 0.0342 0.72 1.4372 0.9589 1413469 IFLab1_001125 CCOC(=O)c1sc(NC(=O)COc2ccccc2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D04 compound treatment 0.336 0.0085 0.33 0.323 -0.00481 -0.1 0.1651 0.473 1079544 IFLab1_001126 FC(F)(F)S(=O)(=O)c1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D05 compound treatment 0.335 0.0075 0.29 0.34 0.0122 0.26 0.3889 0.9974 1600969 IFLab1_001127 CC(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D06 compound treatment 0.351 0.0235 0.92 0.343 0.0152 0.32 0.8781 0.8987 1138171 IFLab1_001128 Fc1ccc(NC(=O)c2cc3cc(Cl)ccc3oc2=N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D07 compound treatment 0.348 0.0205 0.81 0.338 0.0102 0.21 0.7207 0.8644 1108481 IFLab1_001129 O=C(Nc1ccccc1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D08 compound treatment 0.345 0.0175 0.69 0.34 0.0122 0.26 0.6669 0.9088 2066291 IFLab1_001130 FC(F)(F)C(=O)Nc1cccc(c1)C(=O)Nc2cccc(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D09 compound treatment 0.374 0.0465 1.83 0.364 0.0362 0.76 1.8283 0.9239 2066292 IFLab1_001131 COc1ccc(CC2S/C(=N/c3ccc(Br)cc3)/NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D10 compound treatment 0.331 0.0035 0.14 0.361 0.0332 0.69 0.5884 0.8311 1342742 IFLab1_001132 Cc1ccc(cc1)S(=O)(=O)N2CCN(Cc3cc(ccc3O)c4ccccc4)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D11 compound treatment 0.348 0.0205 0.81 0.357 0.0292 0.61 1.0018 0.9906 1650769 IFLab1_001133 COc1ccccc1OCC(=O)Nc2ncc(Cc3ccc(F)cc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D12 compound treatment 0.339 0.0115 0.45 0.321 -0.00681 -0.14 0.2189 0.4618 1985468 IFLab1_001134 CSc1nnc(o1)c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D13 compound treatment 0.34 0.0125 0.49 0.335 0.00719 0.15 0.4539 0.8831 2066293 IFLab1_001135 Cc1ccc(cc1)n2c(C)nc3ccccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D14 compound treatment 0.329 0.0015 0.06 0.338 0.0102 0.21 0.1924 0.87 2066294 IFLab1_001136 Cc1csc2nc(CSc3nnnn3c4ccccc4)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D15 compound treatment 0.31 -0.0175 -0.69 0.339 0.0112 0.23 -0.321 -0.4417 1604901 IFLab1_001137 O=C(NCCc1c[nH]c2ccccc12)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D16 compound treatment 0.32 -0.0075 -0.29 0.321 -0.00681 -0.14 -0.3093 -0.9444 1740346 IFLab1_001138 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccccc3Oc4ccccc4)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D17 compound treatment 0.338 0.0105 0.41 0.343 0.0152 0.32 0.5167 0.9916 1286122 IFLab1_001139 CC(=O)Nc1ccc(cc1N)S(=O)(=O)c2ccc(N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D18 compound treatment 0.338 0.0105 0.41 0.338 0.0102 0.21 0.4427 0.9527 1548282 IFLab1_001140 OC(=O)COc1ccc2c(c1)oc(=O)c3ccccc32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D19 compound treatment 0.334 0.0065 0.26 0.337 0.00919 0.19 0.3167 0.9902 1379754 IFLab1_001141 CC(C)Sc1nc2ccccc2n1CC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D20 compound treatment 0.339 0.0115 0.45 0.343 0.0152 0.32 0.5445 0.9851 1016070 IFLab1_001142 CC(=O)Nc1nc(cs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D21 compound treatment 0.336 0.0085 0.33 0.346 0.0182 0.38 0.5054 0.9979 1385217 IFLab1_001143 Oc1c(CN2CCOCC2)cc(cc1CN3CCOCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D22 compound treatment 0.339 0.0115 0.45 0.339 0.0112 0.23 0.4853 0.9531 1576299 IFLab1_001144 Cn1ccnc1SCC(=O)c2ccc(O)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D23 mock treatment 0.327 -5.0E-4 -0.02 0.327 -8.12E-4 -0.02 -0.0259 -0.9974 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 D24 positive control 0.08 -0.248 -9.73 0.079 -0.249 -5.21 -10.5627 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E01 compound treatment 0.325 -0.0025 -0.1 0.331 0.00319 0.07 -0.0223 -0.1881 1253521 IFLab1_001145 OCCN(CCO)c1ncnc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E02 compound treatment 0.308 -0.0195 -0.77 0.312 -0.0158 -0.33 -0.7761 -0.9294 2066295 IFLab1_001146 CC(=O)Sc1[nH]c(nc1S(=O)(=O)c2ccccc2)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E03 compound treatment 0.325 -0.0025 -0.1 0.304 -0.0238 -0.5 -0.4219 -0.8306 2066296 IFLab1_001147 Cc1nnc2c3cnn(c4ccccc4)c3nc(C)n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E04 compound treatment 0.363 0.0355 1.4 0.338 0.0102 0.21 1.1377 0.8058 1399682 IFLab1_001148 Cc1ccc(cc1)C(=O)Nc2nc(cs2)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E05 compound treatment 0.34 0.0125 0.49 0.327 -8.12E-4 -0.02 0.3355 0.6822 1296769 IFLab1_001149 O=C(CC(=O)c1ccccc1)Nc2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E06 compound treatment 0.367 0.0395 1.55 0.336 0.00819 0.17 1.2193 0.7804 1738796 IFLab1_001150 CCSc1nnc(NC(=O)c2ccc(cc2)C(=O)c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E07 compound treatment 0.313 -0.0145 -0.57 0.303 -0.0248 -0.52 -0.7703 -0.9989 2066297 IFLab1_001151 CCOC(=O)c1c(oc2ccc(OC)cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E08 compound treatment 0.36 0.0325 1.28 0.36 0.0322 0.67 1.3798 0.9552 1715253 IFLab1_001152 Clc1ccccc1c2nnc(NC(=O)Cc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E09 compound treatment 0.356 0.0285 1.12 0.359 0.0312 0.65 1.2538 0.9669 1190551 IFLab1_001153 Oc1ccc2c(=O)c(coc2c1)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E10 compound treatment 0.356 0.0285 1.12 0.357 0.0292 0.61 1.2242 0.9593 1703708 IFLab1_001154 COC(=O)C1=C(CCS1)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E11 compound treatment 0.342 0.0145 0.57 0.345 0.0172 0.36 0.6575 0.9753 1160900 IFLab1_001155 COc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E12 compound treatment 0.388 0.0605 2.38 0.355 0.0272 0.57 2.0843 0.8522 1709683 IFLab1_001156 O=C(Cc1cccc2ccccc12)Nc3nnc(s3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E13 compound treatment 0.341 0.0135 0.53 0.343 0.0152 0.32 0.6001 0.9699 1528674 IFLab1_001157 CCN(CC)S(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)N(CC)CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E14 compound treatment 0.335 0.0075 0.29 0.342 0.0142 0.3 0.4184 1.0 1423396 IFLab1_001158 Cc1nnc(NC(=O)COc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E15 compound treatment 0.342 0.0145 0.57 0.341 0.0132 0.28 0.5983 0.9445 1592334 IFLab1_001159 CC(C)CCOc1cccc(OCC(=O)NCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E16 compound treatment 0.344 0.0165 0.65 0.349 0.0212 0.44 0.7722 0.9828 2066298 IFLab1_001160 CCSc1nnc(NC(=O)c2cccc(c2)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E17 compound treatment 0.342 0.0145 0.57 0.349 0.0212 0.44 0.7166 0.9923 1224629 IFLab1_001161 CCOc1ccc2nc(NC(=O)C3CC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E18 compound treatment 0.343 0.0155 0.61 0.347 0.0192 0.4 0.7149 0.9795 1720680 IFLab1_001162 Oc1ccc(NC(=O)C2CCCCC2)cc1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E19 compound treatment 0.367 0.0395 1.55 0.37 0.0422 0.88 1.7224 0.9642 2066299 IFLab1_001163 O=C(/C(=C/1\Nc2ccccc2S1)/C#N)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E20 compound treatment 0.347 0.0195 0.77 0.362 0.0342 0.72 1.048 0.9994 1124258 IFLab1_001164 O=C(Nc1nc(cs1)c2cccs2)c3ccc(cc3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E21 compound treatment 0.38 0.0525 2.06 0.353 0.0252 0.53 1.8323 0.8601 1674690 IFLab1_001165 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CCN(C)CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E22 compound treatment 0.34 0.0125 0.49 0.335 0.00719 0.15 0.4539 0.8831 1007668 IFLab1_001166 Nc1ccc(NC(=O)CCC(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E23 mock treatment 0.327 -5.0E-4 -0.02 0.329 0.00119 0.02 0.0037 0.1158 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 E24 positive control 0.081 -0.247 -9.69 0.081 -0.247 -5.16 -10.5053 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F01 compound treatment 0.333 0.0055 0.22 0.336 0.00819 0.17 0.2741 0.9934 2066300 IFLab1_001167 CC1CCc2sc(NC(=O)COc3ccc(Cl)cc3)c(C(=O)N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F02 compound treatment 0.335 0.0075 0.29 0.324 -0.00381 -0.08 0.1521 0.4979 1215594 IFLab1_001168 Cc1cc(nc2cc(nn12)C(=O)NCC3CCCO3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F03 compound treatment 0.334 0.0065 0.26 0.364 0.0362 0.76 0.7162 0.8961 1361013 IFLab1_001169 O=C(COc1ccccc1)Nc2nc(cs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F04 compound treatment 0.326 -0.0015 -0.06 0.325 -0.00281 -0.06 -0.0833 -1.0 2066301 IFLab1_001170 CCC(=O)c1ccc2OCCOc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F05 compound treatment 0.359 0.0315 1.24 0.333 0.00519 0.11 0.9525 0.7661 1404125 IFLab1_001171 CC(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)Nc3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F06 compound treatment 0.34 0.0125 0.49 0.337 0.00919 0.19 0.4835 0.9161 1414687 IFLab1_001172 CC1(C)C(OC(=O)C(C)(C)C1=O)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F07 compound treatment 0.348 0.0205 0.81 0.341 0.0132 0.28 0.7651 0.898 1329870 IFLab1_001173 CCN(CC)c1ccc2cc(C(=O)Nc3ccccc3)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F08 compound treatment 0.324 -0.0035 -0.14 0.329 0.00119 0.02 -0.0797 -0.5702 2066302 IFLab1_001174 CCCCC1(C)Cc2ccccc2C(=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F09 compound treatment 0.361 0.0335 1.32 0.373 0.0452 0.95 1.6 0.9868 2066303 IFLab1_001175 COc1ccc(CC2S/C(=N/c3ccccn3)/NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F10 compound treatment 0.348 0.0205 0.81 0.339 0.0112 0.23 0.7355 0.8763 2066304 IFLab1_001176 Clc1ccc(C(=O)Cn2ccnc2)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F11 compound treatment 0.341 0.0135 0.53 0.343 0.0152 0.32 0.6001 0.9699 2066305 IFLab1_001177 COc1ccc(/N=C/c2ccc(o2)c3ccc(F)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F12 compound treatment 0.4 0.0725 2.85 0.382 0.0542 1.13 2.8175 0.9184 2066306 IFLab1_001178 S=C/1SC(=C\C1=C/Nc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F13 compound treatment 0.342 0.0145 0.57 0.339 0.0112 0.23 0.5687 0.9227 1538947 IFLab1_001179 CCCC(NS(=O)(=O)c1ccc(C)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F14 compound treatment 0.343 0.0155 0.61 0.346 0.0182 0.38 0.7001 0.9743 2066307 IFLab1_001180 Clc1ccccc1/N=C/c2ccc(OC(=O)c3cccnc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F15 compound treatment 0.339 0.0115 0.45 0.342 0.0142 0.3 0.5297 0.9792 1619951 IFLab1_001181 Clc1ccc(cc1Cl)C(=O)Oc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F16 compound treatment 0.339 0.0115 0.45 0.346 0.0182 0.38 0.5888 0.9963 2066308 IFLab1_001182 CS(=O)(=O)c1ccc2nc(NC(=O)c3cccc(c3)C(F)(F)F)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F17 compound treatment 0.33 0.0025 0.1 0.334 0.00619 0.13 0.1611 0.9908 1518504 IFLab1_001183 CC(CO)NC(=O)c1cc2ccccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F18 compound treatment 0.347 0.0195 0.77 0.351 0.0232 0.49 0.8852 0.9756 1864906 IFLab1_001184 OC(=O)c1ccccc1NS(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F19 compound treatment 0.343 0.0155 0.61 0.341 0.0132 0.28 0.6261 0.9358 1026952 IFLab1_001185 NC(=O)c1ccc(Oc2ccc(cc2)C(=O)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F20 compound treatment 0.336 0.0085 0.33 0.341 0.0132 0.28 0.4315 0.9955 1172465 IFLab1_001186 O=C1OC(Nc2nccs2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F21 compound treatment 0.344 0.0165 0.65 0.352 0.0242 0.51 0.8166 0.9925 2066309 IFLab1_001187 O=C/1OC(=C\C1=C/Nc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F22 compound treatment 0.336 0.0085 0.33 0.337 0.00919 0.19 0.3723 0.9655 2066310 IFLab1_001188 COc1cc(/C=C\2/N=C(SCC(=O)c3ccccc3)N(C2=O)c4ccccc4)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F23 mock treatment 0.327 -5.0E-4 -0.02 0.307 -0.0208 -0.44 -0.3219 -0.7383 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 F24 positive control 0.081 -0.247 -9.69 0.081 -0.247 -5.16 -10.5053 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G01 compound treatment 0.343 0.0155 0.61 0.332 0.00419 0.09 0.4929 0.8005 1647190 IFLab1_001189 Oc1ccc2ccccc2c1CN3CCN(Cc4ccccc4)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G02 compound treatment 0.312 -0.0155 -0.61 0.315 -0.0128 -0.27 -0.6205 -0.932 2066311 IFLab1_001190 CN1CCN(CC1)C(=O)/C=C/c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G03 compound treatment 0.333 0.0055 0.22 0.325 -0.00281 -0.06 0.1113 0.4966 1731764 IFLab1_001191 O=C(CCN1CCN(Cc2ccccc2)CC1)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G04 compound treatment 0.341 0.0135 0.53 0.331 0.00319 0.07 0.4225 0.7898 2066312 IFLab1_001192 CCSc1nnc(NC(=O)C(C)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G05 compound treatment 0.354 0.0265 1.04 0.337 0.00919 0.19 0.8727 0.8237 2066313 IFLab1_001193 Cc1nc2c(nn(c3ccccc3)c2s1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G06 compound treatment 0.328 5.0E-4 0.02 0.318 -0.00981 -0.21 -0.1313 -0.6365 1566011 IFLab1_001194 CC(=O)Nc1nnc(s1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G07 compound treatment 0.33 0.0025 0.1 0.345 0.0172 0.36 0.3238 0.8685 1342241 IFLab1_001195 COc1ccc2oc(c(C(=O)N(C)C)c2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G08 compound treatment 0.342 0.0145 0.57 0.343 0.0152 0.32 0.6279 0.9619 2066314 IFLab1_001196 CC(C)C(=O)Nc1nnc(s1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G09 compound treatment 0.339 0.0115 0.45 0.346 0.0182 0.38 0.5888 0.9963 1459250 IFLab1_001197 CC(=O)Oc1ccc2c(=O)c(c3nc4ccccc4s3)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G10 compound treatment 0.357 0.0295 1.16 0.358 0.0302 0.63 1.2668 0.9592 1410281 IFLab1_001198 CCCCC(=O)NC1=C(SCC1)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G11 compound treatment 0.331 0.0035 0.14 0.36 0.0322 0.67 0.5736 0.8343 1501543 IFLab1_001199 Cc1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G12 compound treatment 0.345 0.0175 0.69 0.346 0.0182 0.38 0.7557 0.961 1544488 IFLab1_001200 COc1ccc(cc1OC)C(=O)Nc2nnc(s2)c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G13 compound treatment 0.344 0.0165 0.65 0.33 0.00219 0.05 0.4911 0.7551 1156157 IFLab1_001201 Cc1ccccc1Nc2ncc(s2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G14 compound treatment 0.34 0.0125 0.49 0.328 1.88E-4 0.0 0.3503 0.7127 1219723 IFLab1_001202 CCc1nnc(NC(=O)COc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G15 compound treatment 0.33 0.0025 0.1 0.331 0.00319 0.07 0.1167 0.9822 1693047 IFLab1_001203 CC(C)COc1cccc(OCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G16 compound treatment 0.352 0.0245 0.96 0.348 0.0202 0.42 0.9799 0.9316 1615637 IFLab1_001204 Cc1cccc(c1)c2nnc(NC(=O)c3c(F)cccc3F)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G17 compound treatment 0.332 0.0045 0.18 0.335 0.00719 0.15 0.2315 0.9967 1629230 IFLab1_001205 NS(=O)(=O)c1ccc2nc(NC(=O)C3CC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G18 compound treatment 0.333 0.0055 0.22 0.352 0.0242 0.51 0.5108 0.9281 1601099 IFLab1_001206 CSc1nc2ccc(NC(=O)C3CCCCC3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G19 compound treatment 0.341 0.0135 0.53 0.335 0.00719 0.15 0.4817 0.8731 2066315 IFLab1_001207 COc1cc(cc(OC)c1OC)C(=O)/C(=C/2\Nc3ccccc3S2)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G20 compound treatment 0.334 0.0065 0.26 0.338 0.0102 0.21 0.3315 0.9959 1166131 IFLab1_001208 O=C(OCc1nc2ccccc2s1)c3ccc(cc3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G21 compound treatment 0.314 -0.0135 -0.53 0.336 0.00819 0.17 -0.2542 -0.4557 1514992 IFLab1_001209 CN(C)c1ccc(cc1)C(Nc2nccs2)c3ccc4cccnc4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G22 compound treatment 0.335 0.0075 0.29 0.331 0.00319 0.07 0.2557 0.8457 1617268 IFLab1_001210 COC(=O)Cc1csc(=Nc2ccccc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G23 mock treatment 0.319 -0.0085 -0.33 0.322 -0.00581 -0.12 -0.3223 -0.9063 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 G24 positive control 0.081 -0.247 -9.69 0.081 -0.247 -5.16 -10.5053 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H01 compound treatment 0.351 0.0235 0.92 0.353 0.0252 0.53 1.026 0.9646 1738700 IFLab1_001211 CCOc1ccc2nc(NC(=O)COc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H02 compound treatment 0.324 -0.0035 -0.14 0.331 0.00319 0.07 -0.0501 -0.3279 1640509 IFLab1_001212 CCCC1(CC2CC3CC(N)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H03 compound treatment 0.344 0.0165 0.65 0.353 0.0252 0.53 0.8314 0.9947 1352697 IFLab1_001213 O=C(COc1ccccc1)Nc2sc3CCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H04 compound treatment 0.328 5.0E-4 0.02 0.324 -0.00381 -0.08 -0.0425 -0.5174 1609850 IFLab1_001214 Oc1ccc(cc1CN2CCN(CC2)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H05 compound treatment 0.362 0.0345 1.36 0.345 0.0172 0.36 1.2135 0.8647 1353666 IFLab1_001215 COc1ccc(NC(=O)C(C)NC(=O)C(c2ccccc2)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H06 compound treatment 0.335 0.0075 0.29 0.324 -0.00381 -0.08 0.1521 0.4979 1006846 IFLab1_001216 COc1ccc(cc1OC)C(=O)c2ccc(OC)c(OC)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H07 compound treatment 0.337 0.0095 0.37 0.336 0.00819 0.17 0.3853 0.9375 1563664 IFLab1_001217 Cc1cccc(NC(=O)c2cc3c(ccc4ccccc43)oc2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H08 compound treatment 0.338 0.0105 0.41 0.348 0.0202 0.42 0.5906 0.9999 1379899 IFLab1_001218 CC1(C)CC(CC(C)(C)N1)OC(=O)c2ccccc2C(=O)OC3CC(C)(C)NC(C)(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H09 compound treatment 0.348 0.0205 0.81 0.357 0.0292 0.61 1.0018 0.9906 2066316 IFLab1_001219 FC(F)(F)c1cccc(CC2S/C(=N/c3ccccc3)/NC2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H10 compound treatment 0.332 0.0045 0.18 0.345 0.0172 0.36 0.3794 0.9466 1579704 IFLab1_001220 OC(=O)CC(Cc1ccc(Cl)cc1)C(=O)NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H11 compound treatment 0.344 0.0165 0.65 0.346 0.0182 0.38 0.7279 0.9677 2066317 IFLab1_001221 COc1ccc(/N=C/c2ccc(o2)c3ccc(OC)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H12 compound treatment 0.213 -0.115 -4.5 0.218 -0.11 -2.3 -4.8082 -0.9513 2066318 IFLab1_001222 FC(F)(F)c1cccc(c1)c2ccc(/C=C\3/SC(=S)NC3=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H13 compound treatment 0.346 0.0185 0.73 0.336 0.00819 0.17 0.6355 0.8504 1457186 IFLab1_001223 CC1(C)CC(CC(C)(C)N1)OC(=O)CC(=O)OC2CC(C)(C)NC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H14 compound treatment 0.34 0.0125 0.49 0.342 0.0142 0.3 0.5575 0.9709 1007502 IFLab1_001224 OC(=O)CCC(=O)Nc1ccc(Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H15 compound treatment 0.335 0.0075 0.29 0.337 0.00919 0.19 0.3445 0.9785 1265036 IFLab1_001225 CC(C)c1ccc(O)c(CN2CCN(CC2)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H16 compound treatment 0.371 0.0435 1.71 0.37 0.0422 0.88 1.8336 0.9527 1539446 IFLab1_001226 CCOC(=O)Cc1csc(NC(=O)c2sc3ccccc3c2Cl)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H17 compound treatment 0.332 0.0045 0.18 0.328 1.88E-4 0.0 0.1279 0.7226 2066319 IFLab1_001227 CN(Cc1cccs1)C(=S)S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H18 compound treatment 0.333 0.0055 0.22 0.328 1.88E-4 0.0 0.1557 0.7198 2066320 IFLab1_001228 OC(=O)/C=C/c1ccc(cc1)S(=O)(=O)Nc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H19 compound treatment 0.379 0.0515 2.02 0.38 0.0522 1.09 2.204 0.958 1384687 IFLab1_001229 CCOc1ccc2NC(C)(C)c3ssc(=S)c3-c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H20 compound treatment 0.322 -0.0055 -0.22 0.338 0.0102 0.21 -0.0022 -0.0071 1681924 IFLab1_001230 COc1ccc2C(Nc3ccccn3)OC(=O)c2c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H21 compound treatment 0.335 0.0075 0.29 0.336 0.00819 0.17 0.3297 0.9666 2066321 IFLab1_001231 COC(=O)CSc1nnc(o1)c2ccc(Cl)cc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H22 compound treatment 0.339 0.0115 0.45 0.342 0.0142 0.3 0.5297 0.9792 1191458 IFLab1_001232 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H23 mock treatment 0.322 -0.0055 -0.22 0.327 -8.12E-4 -0.02 -0.1649 -0.7604 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 H24 positive control 0.082 -0.246 -9.65 0.082 -0.246 -5.14 -10.4627 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I01 compound treatment 0.351 0.0235 0.92 0.334 0.00619 0.13 0.7449 0.7984 2066322 IFLab1_001233 OC(=O)CCCSc1ncnc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I02 compound treatment 0.336 0.0085 0.33 0.336 0.00819 0.17 0.3575 0.9518 1333100 IFLab1_001234 CC1CCc2sc(NC(=O)C)c(C(=O)N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I03 compound treatment 0.334 0.0065 0.26 0.355 0.0272 0.57 0.583 0.9348 2066323 IFLab1_001235 CCOC(=O)CCSc1ncnc2sc3CCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I04 compound treatment 0.342 0.0145 0.57 0.335 0.00719 0.15 0.5095 0.8641 2066324 IFLab1_001236 CCSc1nnc(NC(=O)CC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I05 compound treatment 0.34 0.0125 0.49 0.345 0.0172 0.36 0.6019 0.9882 2066325 IFLab1_001237 Cc1ccc(NC(=O)CSc2nnc3ccccn23)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I06 compound treatment 0.35 0.0225 0.88 0.344 0.0162 0.34 0.8651 0.9132 1280967 IFLab1_001238 CC(C)C(=O)Nc1nnc(s1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I07 compound treatment 0.361 0.0335 1.32 0.348 0.0202 0.42 1.2301 0.8893 1445143 IFLab1_001239 Oc1ccc2oc(c(C(=O)N3CCCCC3)c2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I08 compound treatment 0.35 0.0225 0.88 0.365 0.0372 0.78 1.1758 0.998 2066326 IFLab1_001240 CC(=O)Nc1nnc(s1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I09 compound treatment 0.349 0.0215 0.85 0.339 0.0112 0.23 0.7633 0.8702 1400911 IFLab1_001241 CC(=O)Oc1ccc2c(=O)c(coc2c1)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I10 compound treatment 0.349 0.0215 0.85 0.352 0.0242 0.51 0.9556 0.9699 1316483 IFLab1_001242 COC(=O)C1=C(CCS1)NC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I11 compound treatment 0.35 0.0225 0.88 0.358 0.0302 0.63 1.0722 0.9864 1614124 IFLab1_001243 COc1ccc2cc(c3nc4ccccc4n3C)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I12 compound treatment 0.341 0.0135 0.53 0.339 0.0112 0.23 0.5409 0.9323 1419025 IFLab1_001244 Cc1ccc(cc1)c2nnc(NC(=O)C3CCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I13 compound treatment 0.36 0.0325 1.28 0.351 0.0232 0.49 1.2467 0.9121 1128737 IFLab1_001245 COc1ccccc1Nc2ncc(s2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I14 compound treatment 0.335 0.0075 0.29 0.341 0.0132 0.28 0.4037 0.9995 1438184 IFLab1_001246 CC(C)c1nnc(NC(=O)COc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I15 compound treatment 0.336 0.0085 0.33 0.339 0.0112 0.23 0.4019 0.9848 1286322 IFLab1_001247 Cc1ccc(OCC(=O)OC2CCS(=O)(=O)C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I16 compound treatment 0.338 0.0105 0.41 0.332 0.00419 0.09 0.3539 0.8385 1188871 IFLab1_001248 COc1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I17 compound treatment 0.34 0.0125 0.49 0.323 -0.00481 -0.1 0.2763 0.5508 1680962 IFLab1_001249 Clc1cccc2sc(NC(=O)C3CC3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I18 compound treatment 0.314 -0.0135 -0.53 0.338 0.0102 0.21 -0.2246 -0.3926 1152746 IFLab1_001250 O=C(Nc1nc(cs1)c2ccc(C#N)cc2)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I19 compound treatment 0.322 -0.0055 -0.22 0.333 0.00519 0.11 -0.0762 -0.3147 2066327 IFLab1_001251 NS(=O)(=O)c1ccc2nc(NC(=O)c3cccc(c3)C(F)(F)F)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I20 compound treatment 0.342 0.0145 0.57 0.317 -0.0108 -0.23 0.2431 0.3964 1317436 IFLab1_001252 CC(=O)Nc1nc(CC(=O)c2ccccc2)cs1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I21 compound treatment 0.269 -0.0585 -2.3 0.266 -0.0618 -1.29 -2.5411 -0.9629 1486508 IFLab1_001253 Oc1c(ccc2cccnc12)C(Nc3ccccc3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I22 compound treatment 0.307 -0.0205 -0.81 0.336 0.00819 0.17 -0.4488 -0.5446 1648546 IFLab1_001254 OC(=O)CCC(=O)Nc1cccc(c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I23 mock treatment 0.33 0.0025 0.1 0.33 0.00219 0.05 0.1019 0.9395 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 I24 positive control 0.083 -0.245 -9.61 0.082 -0.246 -5.14 -10.4349 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J01 compound treatment 0.375 0.0475 1.87 0.368 0.0402 0.84 1.9153 0.9351 1384521 IFLab1_001255 Clc1ccc2nc(NC(=O)COc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J02 compound treatment 0.384 0.0565 2.22 0.391 0.0632 1.32 2.5058 0.9693 1346891 IFLab1_001256 Oc1ccc(cc1)c2cnc(nc2)c3ccc(O)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J03 compound treatment 0.328 5.0E-4 0.02 0.331 0.00319 0.07 0.0611 0.8782 1222630 IFLab1_001257 O=C(COc1ccccc1)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J04 compound treatment 0.333 0.0055 0.22 0.33 0.00219 0.05 0.1853 0.8382 1270037 IFLab1_001258 Cc1cc(Cc2cc(C)c(N)c(C)c2)cc(C)c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J05 compound treatment 0.331 0.0035 0.14 0.332 0.00419 0.09 0.1593 0.9763 1379503 IFLab1_001259 CCOc1cccc2cc(C(=O)OC)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J06 compound treatment 0.331 0.0035 0.14 0.322 -0.00581 -0.12 0.0113 0.0615 1568728 IFLab1_001260 Cc1ccc(cc1)S(=O)(=O)c2cc(C)ccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J07 compound treatment 0.337 0.0095 0.37 0.327 -8.12E-4 -0.02 0.2521 0.6742 1195296 IFLab1_001261 CCOc1cccc2cc(C(=O)Nc3ccc(Cl)cc3Cl)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J08 compound treatment 0.329 0.0015 0.06 0.335 0.00719 0.15 0.1481 0.9164 1723897 IFLab1_001262 CCN(CC)C(=O)c1ccc(Oc2ccc(cc2)C(=O)N(CC)CC)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J09 compound treatment 0.336 0.0085 0.33 0.334 0.00619 0.13 0.3279 0.9148 2066328 IFLab1_001263 CC(=O)Nc1ncc(Cc2cccc(Cl)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J10 compound treatment 0.361 0.0335 1.32 0.346 0.0182 0.38 1.2005 0.8756 1072056 IFLab1_001264 OC(=O)c1cc(Br)c2ccccc2c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J11 compound treatment 0.342 0.0145 0.57 0.34 0.0122 0.26 0.5835 0.9342 1659159 IFLab1_001265 O=C(C1CCCCC1)N2CC(=O)N(CCc3ccccc3)C(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J12 compound treatment 0.318 -0.0095 -0.37 0.349 0.0212 0.44 0.0494 0.0852 2066329 IFLab1_001266 OC(=O)/C=C/c1ccc(o1)c2cccc(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J13 compound treatment 0.347 0.0195 0.77 0.345 0.0172 0.36 0.7965 0.9405 2066330 IFLab1_001267 Clc1cccc(/C=C/2\N=C(OC2=O)c3ccco3)c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J14 compound treatment 0.338 0.0105 0.41 0.358 0.0302 0.63 0.7386 0.9787 2066331 IFLab1_001268 Clc1ccc2nc(nc(c3ccccc3)c2c1)N4CCNCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J15 compound treatment 0.351 0.0235 0.92 0.347 0.0192 0.4 0.9373 0.9303 1161341 IFLab1_001269 Brc1ccc(cc1)C(=O)n2c(=O)oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J16 compound treatment 0.356 0.0285 1.12 0.363 0.0352 0.74 1.313 0.9793 1593267 IFLab1_001270 CCOC(=O)c1csc(NC(=O)c2sc3ccccc3c2Cl)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J17 compound treatment 0.356 0.0285 1.12 0.337 0.00919 0.19 0.9283 0.8165 1359955 IFLab1_001271 CCOC(=O)c1cnc2c3nsnc3ccc2c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J18 compound treatment 0.343 0.0155 0.61 0.346 0.0182 0.38 0.7001 0.9743 1360581 IFLab1_001272 O=S(=O)(N1CCCCC1)c2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J19 compound treatment 0.303 -0.0245 -0.96 0.311 -0.0168 -0.35 -0.9299 -0.9068 1702645 IFLab1_001273 CCOC(=O)c1c(OCC)[nH]c2c1cc(O)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J20 compound treatment 0.349 0.0215 0.85 0.35 0.0222 0.46 0.9261 0.9602 1220831 IFLab1_001274 O=C1OC(Nc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J21 compound treatment 0.346 0.0185 0.73 0.353 0.0252 0.53 0.887 0.9875 1186914 IFLab1_001275 NC(=O)CSc1nc2ccccc2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J22 compound treatment 0.351 0.0235 0.92 0.351 0.0232 0.49 0.9965 0.9548 1219595 IFLab1_001276 CC(C)C(=O)Nc1nc(cs1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J23 mock treatment 0.324 -0.0035 -0.14 0.307 -0.0208 -0.44 -0.4053 -0.8873 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 J24 positive control 0.084 -0.243 -9.57 0.083 -0.245 -5.12 -10.3923 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K01 compound treatment 0.35 0.0225 0.88 0.347 0.0192 0.4 0.9095 0.9361 1786302 IFLab1_001277 OC(=O)CCc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K02 compound treatment 0.332 0.0045 0.18 0.324 -0.00381 -0.08 0.0687 0.3539 1436253 IFLab1_001278 CC(C)C(=O)Nc1sc2CCC(C)Cc2c1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K03 compound treatment 0.331 0.0035 0.14 0.334 0.00619 0.13 0.1889 0.9995 1477975 IFLab1_001279 CN1CCN(CC1)S(=O)(=O)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K04 compound treatment 0.335 0.0075 0.29 0.328 1.88E-4 0.0 0.2113 0.7165 1116592 IFLab1_001280 CCSc1nnc(NC(=O)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K05 compound treatment 0.327 -5.0E-4 -0.02 0.329 0.00119 0.02 0.0037 0.1158 1067361 IFLab1_001281 OC(=O)c1ccccc1C(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K06 compound treatment 0.375 0.0475 1.87 0.364 0.0362 0.76 1.8561 0.921 2066332 IFLab1_001282 Cc1cccc(c1)c2nnc(NC(=O)C(C)(C)C)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K07 compound treatment 0.348 0.0205 0.81 0.331 0.00319 0.07 0.6171 0.763 1444429 IFLab1_001283 CN(C)C(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K08 compound treatment 0.34 0.0125 0.49 0.356 0.0282 0.59 0.7646 0.9959 2066333 IFLab1_001284 Clc1ccc(cc1)c2nnc(NC(=O)CBr)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K09 compound treatment 0.359 0.0315 1.24 0.372 0.0442 0.92 1.5296 0.9896 1922320 IFLab1_001285 CCc1cc2c(=O)c(c3nc4ccccc4n3C)c(oc2cc1O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K10 compound treatment 0.365 0.0375 1.47 0.368 0.0402 0.84 1.6372 0.9646 1461478 IFLab1_001286 COC(=O)C1=C(CCS1)NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K11 compound treatment 0.351 0.0235 0.92 0.341 0.0132 0.28 0.8485 0.8799 1163362 IFLab1_001287 CCc1cc(c2n[nH]cc2c3nc4ccccc4n3C)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K12 compound treatment 0.351 0.0235 0.92 0.35 0.0222 0.46 0.9817 0.9493 1511522 IFLab1_001288 Fc1cccc(c1)C(=O)Nc2nnc(s2)c3ccc(Cl)cc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K13 compound treatment 0.328 5.0E-4 0.02 0.348 0.0202 0.42 0.3126 0.7392 2066334 IFLab1_001289 OC(=O)CSc1nnc(COc2ccccc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K14 compound treatment 0.346 0.0185 0.73 0.339 0.0112 0.23 0.6799 0.8897 2066335 IFLab1_001290 CC(C)c1nnc(NC(=O)c2c(F)cccc2F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K15 compound treatment 0.344 0.0165 0.65 0.346 0.0182 0.38 0.7279 0.9677 1728810 IFLab1_001291 CC(NC(=O)COc1ccc(C)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K16 compound treatment 0.375 0.0475 1.87 0.366 0.0382 0.8 1.8857 0.9283 1588522 IFLab1_001292 Clc1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K17 compound treatment 0.355 0.0275 1.08 0.359 0.0312 0.65 1.226 0.9708 1371960 IFLab1_001293 O=C(Nc1nc2c(ccc3ccccc23)s1)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K18 compound treatment 0.342 0.0145 0.57 0.341 0.0132 0.28 0.5983 0.9445 1606388 IFLab1_001294 CCOC(=O)c1csc(NC(=O)C2CCCCC2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K19 compound treatment 0.339 0.0115 0.45 0.335 0.00719 0.15 0.4261 0.8941 1213849 IFLab1_001295 Cc1cccc2nc(CNc3ccc(I)cc3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K20 compound treatment 0.321 -0.0065 -0.26 0.326 -0.00181 -0.04 -0.2075 -0.8033 1483792 IFLab1_001296 CC(=O)Nc1ccc2nc(NC(=O)c3cc(Cl)ccc3Cl)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K21 compound treatment 0.336 0.0085 0.33 0.341 0.0132 0.28 0.4315 0.9955 1687669 IFLab1_001297 Fc1ccc(cc1)c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K22 compound treatment 0.336 0.0085 0.33 0.345 0.0172 0.36 0.4906 0.9993 1233139 IFLab1_001298 Cc1cccc(NC(=O)CCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K23 mock treatment 0.331 0.0035 0.14 0.325 -0.00281 -0.06 0.0557 0.3721 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 K24 positive control 0.086 -0.241 -9.5 0.085 -0.243 -5.08 -10.3071 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L01 compound treatment 0.343 0.0155 0.61 0.345 0.0172 0.36 0.6853 0.9684 1476952 IFLab1_001299 O=C(COc1ccccc1)Nc2nc3CCCCc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L02 compound treatment 0.319 -0.0085 -0.33 0.328 1.88E-4 0.0 -0.2335 -0.6988 1522785 IFLab1_001300 CCc1ccc(OCC(=O)NCCc2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L03 compound treatment 0.343 0.0155 0.61 0.354 0.0262 0.55 0.8184 0.9986 1687354 IFLab1_001301 CCCC(=O)Nc1ccccc1c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L04 compound treatment 0.331 0.0035 0.14 0.325 -0.00281 -0.06 0.0557 0.3721 1616457 IFLab1_001302 CC1(C)CC(=O)C=C(C1)NCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L05 compound treatment 0.353 0.0255 1.0 0.349 0.0212 0.44 1.0225 0.9327 1539653 IFLab1_001303 CCN(CC)c1ccc2cc(C#N)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L06 compound treatment 0.334 0.0065 0.26 0.334 0.00619 0.13 0.2723 0.9503 2066336 IFLab1_001304 Brc1ccc(/C=C/2\N=C(OC2=O)c3ccco3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L07 compound treatment 0.358 0.0305 1.2 0.361 0.0332 0.69 1.339 0.9663 1508244 IFLab1_001305 CCOc1cccc2cc(c3nc4ccccc4[nH]3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L08 compound treatment 0.34 0.0125 0.49 0.35 0.0222 0.46 0.6758 0.9996 2066337 IFLab1_001306 Cc1c(Cl)cccc1N/C=C/2\N=C(OC2=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L09 compound treatment 0.358 0.0305 1.2 0.331 0.00319 0.07 0.8951 0.7453 2066338 IFLab1_001307 CC(=O)Nc1ncc(Cc2ccc(C)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L10 compound treatment 0.338 0.0105 0.41 0.337 0.00919 0.19 0.4279 0.9395 1779852 IFLab1_001308 C/C(=C\C(=O)O)/C=C/c1cccnc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L11 compound treatment 0.334 0.0065 0.26 0.333 0.00519 0.11 0.2575 0.9273 1229167 IFLab1_001309 C(Cn1c(NCc2cccs2)nc3ccccc13)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L12 compound treatment 0.358 0.0305 1.2 0.358 0.0302 0.63 1.2946 0.9552 2066339 IFLab1_001310 OC(=O)/C=C/c1ccc(o1)c2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L13 compound treatment 0.331 0.0035 0.14 0.346 0.0182 0.38 0.3664 0.9054 1686133 IFLab1_001311 Oc1cc(O)cc(c1)C(=O)Nc2cccc(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L14 compound treatment 0.343 0.0155 0.61 0.343 0.0152 0.32 0.6557 0.9539 1683189 IFLab1_001312 CC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L15 compound treatment 0.342 0.0145 0.57 0.332 0.00419 0.09 0.4651 0.8063 1570094 IFLab1_001313 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2cccc(F)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L16 compound treatment 0.334 0.0065 0.26 0.351 0.0232 0.49 0.5238 0.9552 2066340 IFLab1_001314 Clc1c(sc2ccccc12)/C(=C\3/Nc4ccccc4S3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L17 compound treatment 0.334 0.0065 0.26 0.356 0.0282 0.59 0.5978 0.9299 1600394 IFLab1_001315 COc1cccc(c1)C(=O)Nc2cccc(c2)c3nc4ncccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L18 compound treatment 0.348 0.0205 0.81 0.33 0.00219 0.05 0.6023 0.7461 1478136 IFLab1_001316 OC(=O)c1ccc(cc1)S(=O)(=O)N2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L19 compound treatment 0.326 -0.0015 -0.06 0.329 0.00119 0.02 -0.0241 -0.3771 1426498 IFLab1_001317 CCOC(=O)C1C(C(C(=O)OCC)C(C)(O)CC1=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L20 compound treatment 0.438 0.111 4.34 0.432 0.104 2.18 4.6138 0.9491 1625442 IFLab1_001318 COc1ccc(cc1)c2nc3SCCn3c2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L21 compound treatment 0.347 0.0195 0.77 0.353 0.0252 0.53 0.9148 0.9833 2066341 IFLab1_001319 CC(=O)N/C(=C\c1ccccc1)/C(=O)Nc2cc(C)cc(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L22 compound treatment 0.35 0.0225 0.88 0.35 0.0222 0.46 0.9539 0.9547 1524726 IFLab1_001320 Fc1cccc(F)c1C(=O)Nc2nc(cs2)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L23 mock treatment 0.328 5.0E-4 0.02 0.327 -8.12E-4 -0.02 0.0019 0.0723 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 L24 positive control 0.085 -0.242 -9.53 0.085 -0.243 -5.08 -10.3349 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M01 compound treatment 0.334 0.0065 0.26 0.337 0.00919 0.19 0.3167 0.9902 1138428 IFLab1_001321 COc1ccccc1C(=O)Nc2ncnc3sc4CCCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M02 compound treatment 0.38 0.0525 2.06 0.376 0.0482 1.01 2.1726 0.9457 1292616 IFLab1_001322 COc1ccccc1C(=O)Nc2sc3CCC(C)Cc3c2C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M03 compound treatment 0.346 0.0185 0.73 0.348 0.0202 0.42 0.8131 0.9666 2066342 IFLab1_001323 Cc1cccc(NC(=O)CSc2nnnn2c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M04 compound treatment 0.329 0.0015 0.06 0.327 -8.12E-4 -0.02 0.0297 0.4836 1124649 IFLab1_001324 CCSc1nnc(NC(=O)c2ccc(OC)cc2OC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M05 compound treatment 0.343 0.0155 0.61 0.314 -0.0138 -0.29 0.2265 0.3359 1293606 IFLab1_001325 COc1ccc(cc1OC)C(=O)NCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M06 compound treatment 0.335 0.0075 0.29 0.334 0.00619 0.13 0.3001 0.9317 1195031 IFLab1_001326 Cc1cccc(c1)c2nnc(NC(=O)Cc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M07 compound treatment 0.323 -0.0045 -0.18 0.327 -8.12E-4 -0.02 -0.1371 -0.7715 1371174 IFLab1_001327 CCOC(=O)c1c(C)oc2ccc(OC(=O)c3ccco3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M08 compound treatment 0.339 0.0115 0.45 0.339 0.0112 0.23 0.4853 0.9531 2066343 IFLab1_001328 CCC(=O)Nc1nnc(s1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M09 compound treatment 0.345 0.0175 0.69 0.335 0.00719 0.15 0.5929 0.8418 1220572 IFLab1_001329 CC(=O)Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M10 compound treatment 0.408 0.0805 3.17 0.407 0.0792 1.66 3.4098 0.9544 2066344 IFLab1_001330 COC(=O)C1=C(CCS1)NC(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M11 compound treatment 0.351 0.0235 0.92 0.382 0.0542 1.13 1.4552 0.9948 2066345 IFLab1_001331 Oc1ccc(c2n[nH]cc2c3nc4ccccc4s3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M12 compound treatment 0.359 0.0315 1.24 0.35 0.0222 0.46 1.2041 0.9103 1147068 IFLab1_001332 CCSc1nnc(NC(=O)COc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M13 compound treatment 0.349 0.0215 0.85 0.349 0.0212 0.44 0.9113 0.9546 1384402 IFLab1_001333 OC(=O)CNC(=O)COc1ccc(Oc2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M14 compound treatment 0.362 0.0345 1.36 0.362 0.0342 0.72 1.465 0.9553 1628487 IFLab1_001334 CCC(CC)C(=O)Nc1nnc(s1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M15 compound treatment 0.359 0.0315 1.24 0.345 0.0172 0.36 1.1301 0.8763 2066346 IFLab1_001335 COc1ccc(cc1)C(=O)/C(=C/2\Nc3ccccc3S2)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M16 compound treatment 0.358 0.0305 1.2 0.352 0.0242 0.51 1.2059 0.9264 1582551 IFLab1_001336 Cc1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M17 compound treatment 0.346 0.0185 0.73 0.351 0.0232 0.49 0.8574 0.9806 1348132 IFLab1_001337 CCOC(=O)c1sc(NC(=O)C2CC2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M18 compound treatment 0.345 0.0175 0.69 0.328 1.88E-4 0.0 0.4893 0.7111 1493938 IFLab1_001338 COc1ccc(NC(=O)C2CCCCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M19 compound treatment 0.343 0.0155 0.61 0.339 0.0112 0.23 0.5965 0.9136 1502606 IFLab1_001339 Cc1cccc2nc(CSc3ccccc3N)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M20 compound treatment 0.338 0.0105 0.41 0.337 0.00919 0.19 0.4279 0.9395 2066347 IFLab1_001340 Clc1ccc(Cl)c(c1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M21 compound treatment 0.328 5.0E-4 0.02 0.347 0.0192 0.4 0.2978 0.7408 1684460 IFLab1_001341 Cc1cccn2cc(COc3ccc(Cl)cc3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M22 compound treatment 0.35 0.0225 0.88 0.35 0.0222 0.46 0.9539 0.9547 2066348 IFLab1_001342 Oc1nc(c2ccccc2)c3cc(Cl)ccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M23 mock treatment 0.333 0.0055 0.22 0.334 0.00619 0.13 0.2445 0.9699 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 M24 positive control 0.087 -0.24 -9.46 0.087 -0.241 -5.04 -10.2497 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N01 compound treatment 0.349 0.0215 0.85 0.344 0.0162 0.34 0.8373 0.9194 1657252 IFLab1_001343 Cn1c(=NC(=O)COc2ccccc2)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N02 compound treatment 0.334 0.0065 0.26 0.336 0.00819 0.17 0.3019 0.9811 1537341 IFLab1_001344 OC(=O)CCCN1CCS(=O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N03 compound treatment 0.349 0.0215 0.85 0.346 0.0182 0.38 0.8669 0.9351 2066349 IFLab1_001345 CCCC(=O)Nc1nc(cs1)c2ccc(Cl)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N04 compound treatment 0.526 0.199 7.8 0.508 0.18 3.77 8.185 0.9443 1983568 IFLab1_001346 CCN(CC)c1ccc2ccc(O)cc2[o+]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N05 compound treatment 0.349 0.0215 0.85 0.34 0.0122 0.26 0.7781 0.8812 1386125 IFLab1_001347 CCOc1cccc2cc(C#N)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N06 compound treatment 0.337 0.0095 0.37 0.337 0.00919 0.19 0.4001 0.9523 1561072 IFLab1_001348 COc1ccc(cc1)C(=O)NC2=C(C)N(C)N(C2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N07 compound treatment 0.378 0.0505 1.99 0.362 0.0342 0.72 1.9099 0.9049 1489044 IFLab1_001349 c1ccc2oc(nc2c1)c3ccnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N08 compound treatment 0.379 0.0515 2.02 0.358 0.0302 0.63 1.8785 0.8856 1721659 IFLab1_001350 CCOC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N09 compound treatment 0.354 0.0265 1.04 0.353 0.0252 0.53 1.1095 0.9502 2066350 IFLab1_001351 CC(C)C(=O)Nc1ncc(Cc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N10 compound treatment 0.334 0.0065 0.26 0.332 0.00419 0.09 0.2427 0.8982 1285926 IFLab1_001352 CCC1(CC2CC3CC(N)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N11 compound treatment 0.362 0.0345 1.36 0.368 0.0402 0.84 1.5538 0.9736 1697548 IFLab1_001353 Nc1ccc(c2nc3ccccc3[nH]2)c(N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N12 compound treatment 0.384 0.0565 2.22 0.393 0.0652 1.36 2.5354 0.9726 1782504 IFLab1_001354 Fc1ccc(cc1)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N13 compound treatment 0.356 0.0285 1.12 0.344 0.0162 0.34 1.0319 0.8815 1628850 IFLab1_001355 COc1ccc2[nH]c3C(C)NCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N14 compound treatment 0.353 0.0255 1.0 0.357 0.0292 0.61 1.1408 0.9718 1372885 IFLab1_001356 CS(=O)(=O)c1ccc2nc(NC(=O)C3CC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N15 compound treatment 0.343 0.0155 0.61 0.342 0.0142 0.3 0.6409 0.9454 1326463 IFLab1_001357 COc1ccccc1Nc2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N16 compound treatment 0.344 0.0165 0.65 0.343 0.0152 0.32 0.6835 0.9461 1781991 IFLab1_001358 O=S(=O)(/C=C/c1ccccc1)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N17 compound treatment 0.347 0.0195 0.77 0.347 0.0192 0.4 0.8261 0.9545 1258045 IFLab1_001359 CC(C)(C)c1cc(CN2CCOCC2)c(O)c(CN3CCOCC3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N18 compound treatment 0.345 0.0175 0.69 0.351 0.0232 0.49 0.8296 0.9854 1016773 IFLab1_001360 CCOC(=O)CSc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N19 compound treatment 0.325 -0.0025 -0.1 0.331 0.00319 0.07 -0.0223 -0.1881 1141026 IFLab1_001361 CC(C)c1ccc(C)c(Oc2cc(Cl)nc(N)n2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N20 compound treatment 0.33 0.0025 0.1 0.338 0.0102 0.21 0.2203 0.9382 2066351 IFLab1_001362 O=C(Cn1c(c[n+]2ccsc12)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N21 compound treatment 0.348 0.0205 0.81 0.331 0.00319 0.07 0.6171 0.763 1585073 IFLab1_001363 CCc1ccc(OCC(=O)Nc2cccc(Cl)c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N22 compound treatment 0.337 0.0095 0.37 0.347 0.0192 0.4 0.548 0.9993 1287641 IFLab1_001364 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N23 mock treatment 0.331 0.0035 0.14 0.338 0.0102 0.21 0.2481 0.9776 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 N24 positive control 0.086 -0.241 -9.5 0.088 -0.24 -5.02 -10.2627 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O01 compound treatment 0.343 0.0155 0.61 0.344 0.0162 0.34 0.6705 0.9616 1381740 IFLab1_001365 O=S(=O)(N1CCN(Cc2ccccc2)CC1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O02 compound treatment 0.349 0.0215 0.85 0.344 0.0162 0.34 0.8373 0.9194 1226038 IFLab1_001366 CC1CCc2sc(NC(=O)c3cccs3)c(C(=O)N)c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O03 compound treatment 0.356 0.0285 1.12 0.351 0.0232 0.49 1.1355 0.9299 2066352 IFLab1_001367 CCOC(=O)c1c(NC(=O)/C=C/c2ccco2)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O04 compound treatment 0.337 0.0095 0.37 0.326 -0.00181 -0.04 0.2373 0.6321 1257242 IFLab1_001368 CCSc1nnc(NC(=O)c2ccccc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O05 compound treatment 0.328 5.0E-4 0.02 0.334 0.00619 0.13 0.1055 0.8052 1432965 IFLab1_001369 CCOC(=O)c1c(oc2ccc(OC(=O)CC)cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O06 compound treatment 0.351 0.0235 0.92 0.342 0.0142 0.3 0.8633 0.8895 1555885 IFLab1_001370 COc1ccccc1C(=O)Nc2nnc(s2)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O07 compound treatment 0.334 0.0065 0.26 0.338 0.0102 0.21 0.3315 0.9959 1315017 IFLab1_001371 CCOC(=O)c1c(oc2ccc(O)c(CN3CCOCC3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O08 compound treatment 0.344 0.0165 0.65 0.342 0.0142 0.3 0.6687 0.9372 1634705 IFLab1_001372 Clc1ccc(cc1)c2nnc(NC(=O)C3CCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O09 compound treatment 0.543 0.216 8.47 0.604 0.276 5.78 10.0781 0.9826 1422999 IFLab1_001373 CN(C)Cc1c(O)ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O10 compound treatment 0.366 0.0385 1.51 0.345 0.0172 0.36 1.3247 0.8514 1133059 IFLab1_001374 COC(=O)C1=C(CCS1)NC(=O)Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O11 compound treatment 0.544 0.217 8.51 0.547 0.219 4.59 9.2625 0.9579 1235738 IFLab1_001375 CCC1CCCCN1Cc2c(O)ccc3cc(c4nc(C)cs4)c(=O)oc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O12 compound treatment 0.371 0.0435 1.71 0.377 0.0492 1.03 1.9372 0.9705 2066353 IFLab1_001376 COC(=O)C1=C(CCS1)NC(=O)CCCCl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O13 compound treatment 0.343 0.0155 0.61 0.349 0.0212 0.44 0.7444 0.9878 1711670 IFLab1_001377 COc1cccc(OCC(=O)Oc2ccc(cc2)C(=O)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O14 compound treatment 0.353 0.0255 1.0 0.359 0.0312 0.65 1.1704 0.9784 2066354 IFLab1_001378 FC(F)(F)c1cccc(c1)C(=O)Nc2nnc(s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O15 compound treatment 0.335 0.0075 0.29 0.33 0.00219 0.05 0.2409 0.8072 1178511 IFLab1_001379 CCOC(=O)c1c(NC(=O)C2CC2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O16 compound treatment 0.348 0.0205 0.81 0.353 0.0252 0.53 0.9426 0.9788 1518941 IFLab1_001380 NS(=O)(=O)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O17 compound treatment 0.347 0.0195 0.77 0.349 0.0212 0.44 0.8557 0.9661 1584919 IFLab1_001381 COc1ccc(NC(=O)C2CC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O18 compound treatment 0.347 0.0195 0.77 0.342 0.0142 0.3 0.7521 0.9147 1713763 IFLab1_001382 Brc1ccc2nc(NC(=O)c3ccc(cc3)N4C(=O)CCC4=O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O19 compound treatment 0.331 0.0035 0.14 0.34 0.0122 0.26 0.2776 0.9581 2066355 IFLab1_001383 COc1ccc(cc1)C(=O)OCc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O20 compound treatment 0.344 0.0165 0.65 0.329 0.00119 0.02 0.4763 0.7337 2066356 IFLab1_001384 Cc1csc(Nc2ccccc2)[n+]1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O21 compound treatment 0.345 0.0175 0.69 0.346 0.0182 0.38 0.7557 0.961 1177653 IFLab1_001385 C(SC1=NCCS1)c2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O22 compound treatment 0.34 0.0125 0.49 0.343 0.0152 0.32 0.5723 0.9777 2066357 IFLab1_001386 Oc1nc(c2ccccc2)c3cc(Br)ccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O23 mock treatment 0.331 0.0035 0.14 0.327 -8.12E-4 -0.02 0.0853 0.6151 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 O24 positive control 0.089 -0.238 -9.38 0.09 -0.238 -4.98 -10.1497 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P01 compound treatment 0.35 0.0225 0.88 0.34 0.0122 0.26 0.8059 0.8753 1566344 IFLab1_001387 CSc1nc2ccc(NC(=O)COc3ccccc3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P02 compound treatment 0.355 0.0275 1.08 0.335 0.00719 0.15 0.8709 0.7978 1915775 IFLab1_001388 OC(=O)CN(CCCc1ccccc1)CC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P03 compound treatment 0.355 0.0275 1.08 0.347 0.0192 0.4 1.0485 0.909 2066358 IFLab1_001389 CCCC(=O)Nc1nc2CCC(C)Cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P04 compound treatment 0.365 0.0375 1.47 0.366 0.0382 0.8 1.6076 0.9586 2066359 IFLab1_001390 CC(NC(=O)C(C)(C)C)C1CC2CCC1C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P05 compound treatment 0.385 0.0575 2.26 0.383 0.0552 1.15 2.4152 0.9514 1328544 IFLab1_001391 COc1ccccc1NC(=O)c2cc3ccccc3oc2=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P06 compound treatment 0.369 0.0415 1.63 0.357 0.0292 0.61 1.5857 0.9101 1163900 IFLab1_001392 CCOC(=O)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P07 compound treatment 0.367 0.0395 1.55 0.384 0.0562 1.18 1.9296 0.9906 2066360 IFLab1_001393 CCOc1ccc(CC2SC(=N)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P08 compound treatment 0.382 0.0545 2.14 0.393 0.0652 1.36 2.4798 0.9762 1221857 IFLab1_001394 O=C1CN(CC(=O)N1CCc2ccccc2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P09 compound treatment 0.417 0.0895 3.52 0.399 0.0712 1.49 3.5416 0.9268 1360916 IFLab1_001395 COc1ccc(Cc2cnc(NC(=O)Cc3ccccc3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P10 compound treatment 0.392 0.0645 2.54 0.391 0.0632 1.32 2.7282 0.9539 2066361 IFLab1_001396 CC(=C)C(=O)Nc1ccc(cc1)c2nc3cc(NC(=O)C(=C)C)ccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P11 compound treatment 0.39 0.0625 2.46 0.386 0.0582 1.22 2.5986 0.9475 1140011 IFLab1_001397 Cc1ccc(OCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P12 compound treatment 0.392 0.0645 2.54 0.39 0.0622 1.3 2.7134 0.9519 1782503 IFLab1_001398 COc1ccc(cc1)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P13 compound treatment 0.377 0.0495 1.95 0.379 0.0512 1.07 2.1336 0.9604 2066362 IFLab1_001399 O=S1(=O)N=C(NCc2ccccc2)c3ccccc31 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P14 compound treatment 0.377 0.0495 1.95 0.391 0.0632 1.32 2.3112 0.9823 1139871 IFLab1_001400 Cc1ccc(cc1)C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P15 compound treatment 0.363 0.0355 1.4 0.366 0.0382 0.8 1.552 0.965 1041788 IFLab1_001401 CN1CCCC1c2cccnc2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P16 compound treatment 0.376 0.0485 1.91 0.375 0.0472 0.99 2.0466 0.9531 2066363 IFLab1_001402 CS(=O)(=O)c1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P17 compound treatment 0.369 0.0415 1.63 0.363 0.0352 0.74 1.6745 0.9354 1395261 IFLab1_001403 CC1(C)CC(CC(C)(C)N1)NC(=O)CNc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P18 compound treatment 0.345 0.0175 0.69 0.352 0.0242 0.51 0.8444 0.9886 1645376 IFLab1_001404 CCOC(=O)c1c(oc2ccc(OC(C)C(=O)OC)cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P19 compound treatment 0.346 0.0185 0.73 0.349 0.0212 0.44 0.8279 0.9718 1343506 IFLab1_001405 Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P20 compound treatment 0.358 0.0305 1.2 0.352 0.0242 0.51 1.2059 0.9264 1100932 IFLab1_001406 C1Cn2cc(nc2S1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P21 compound treatment 0.354 0.0265 1.04 0.369 0.0412 0.86 1.3462 0.9956 1705627 IFLab1_001407 CC(=O)Oc1ccc(cc1)C(=O)Nc2cc(Cl)ccc2OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P22 compound treatment 0.346 0.0185 0.73 0.344 0.0162 0.34 0.7539 0.9395 1577296 IFLab1_001408 CCCC(=O)Nc1nc(cs1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P23 mock treatment 0.337 0.0095 0.37 0.346 0.0182 0.38 0.5332 1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1415 P24 positive control 0.092 -0.235 -9.26 0.093 -0.235 -4.91 -10.0219 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A01 compound treatment 0.352 0.0251 0.99 0.34 0.0121 0.25 0.8753 0.8605 1743162 IFLab1_001409 CN(C)c1ccc(cc1)C(=O)Nc2nc3ccc(Cl)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A02 compound treatment 0.322 -0.00494 -0.19 0.348 0.0201 0.42 0.1596 0.345 2066364 IFLab1_001410 CC(=O)Nc1nc(cs1)c2cc(Cl)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A03 compound treatment 0.321 -0.00594 -0.23 0.323 -0.00494 -0.1 -0.2381 -0.9328 1275248 IFLab1_001411 CC(=O)Nc1ccc2nc(NC(=O)CCOc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A04 compound treatment 0.498 0.171 6.73 0.489 0.161 3.37 7.1391 0.949 2066365 IFLab1_001412 COc1ccc(/C=C\2/SC(=S)N(C(C)C(=O)O)C2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A05 compound treatment 0.327 6.25E-5 0.0 0.319 -0.00894 -0.19 -0.1305 -0.6978 1150681 IFLab1_001413 CCOc1ccc(OCC)c(c1)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A06 compound treatment 0.358 0.0311 1.22 0.338 0.0101 0.21 1.0125 0.817 2066366 IFLab1_001414 Clc1ccccc1NC(=O)CN2C(=O)S/C(=C/c3ccccc3)/C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A07 compound treatment 0.173 -0.154 -6.05 0.157 -0.171 -3.58 -6.8092 -0.9685 2066367 IFLab1_001415 CCN1C(=O)/C(=C\C=C\c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A08 compound treatment 0.351 0.0241 0.95 0.341 0.0131 0.27 0.8623 0.8756 2066368 IFLab1_001416 CC(C)(C)NC(=O)CN1C(=O)S/C(=C\c2ccccc2)/C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A09 compound treatment 0.324 -0.00294 -0.12 0.34 0.0121 0.25 0.0968 0.3488 1157814 IFLab1_001417 Fc1ccccc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A10 compound treatment 0.372 0.0451 1.77 0.331 0.00306 0.06 1.2981 0.7322 2066369 IFLab1_001418 CCC(=O)Nc1c2CSCc2nn1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A11 compound treatment 0.329 0.00206 0.08 0.327 -9.37E-4 -0.02 0.0435 0.521 2066370 IFLab1_001419 O/N=C/c1cn(CCC#N)nc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A12 compound treatment 0.339 0.0121 0.47 0.36 0.0321 0.67 0.8098 0.9856 1130107 IFLab1_001420 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A13 compound treatment 0.333 0.00606 0.24 0.332 0.00406 0.09 0.2287 0.9036 1258421 IFLab1_001421 CSCCC(N1C(=O)CSC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A14 compound treatment 0.333 0.00606 0.24 0.331 0.00306 0.06 0.2139 0.8664 1742527 IFLab1_001422 CC(=O)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A15 compound treatment 0.36 0.0331 1.3 0.32 -0.00794 -0.17 0.8018 0.6118 2066371 IFLab1_001423 CN1CCN(CC1)C(=O)CCN2C(=O)S/C(=C/c3ccc(C)cc3)/C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A16 compound treatment 0.35 0.0231 0.91 0.347 0.0191 0.4 0.9233 0.932 1561178 IFLab1_001424 Fc1ccc(COc2ccc3ccc(=O)oc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A17 compound treatment 0.328 0.00106 0.04 0.351 0.0231 0.48 0.3708 0.7655 2066372 IFLab1_001425 COc1cccc(/C=C/2\SC(=O)N(CCC(=O)O)C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A18 compound treatment 0.348 0.0211 0.83 0.328 6.25E-5 0.0 0.5865 0.7082 1347239 IFLab1_001426 COC(=O)C(C)Oc1ccc2c(C)cc(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A19 compound treatment 0.43 0.103 4.05 0.42 0.0921 1.93 4.2276 0.9422 2066373 IFLab1_001427 CCCC(N1C(=O)/C(=C/c2ccccc2Cl)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A20 compound treatment 0.325 -0.00194 -0.08 0.344 0.0161 0.34 0.1838 0.5333 2066374 IFLab1_001428 CCCc1cc(=O)oc2cc(OC)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A21 compound treatment 0.333 0.00606 0.24 0.317 -0.0109 -0.23 0.0067 0.0203 1647010 IFLab1_001429 Oc1c(CN2CCCC2=O)cc(Cl)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A22 compound treatment 0.323 -0.00394 -0.15 0.324 -0.00394 -0.08 -0.1677 -0.9564 1718551 IFLab1_001430 CC(=O)Oc1ccc2c(cc(=O)oc2c1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A23 mock treatment 0.322 -0.00494 -0.19 0.343 0.0151 0.32 0.0856 0.2313 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 A24 positive control 0.078 -0.249 -9.79 0.079 -0.249 -5.21 -10.6045 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B01 compound treatment 0.336 0.00906 0.36 0.347 0.0191 0.4 0.534 0.9984 1417741 IFLab1_001431 CCOc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B02 compound treatment 0.32 -0.00694 -0.27 0.325 -0.00294 -0.06 -0.2363 -0.8453 1377384 IFLab1_001432 O=C(Nc1nc(cs1)c2ccccc2)c3cc(=O)c4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B03 compound treatment 0.377 0.0501 1.97 0.362 0.0341 0.71 1.8959 0.9056 1250399 IFLab1_001433 Oc1cc(O)c2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B04 compound treatment 0.332 0.00506 0.2 0.327 -9.37E-4 -0.02 0.1269 0.6343 1678427 IFLab1_001434 CCOC(=O)c1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B05 compound treatment 0.332 0.00506 0.2 0.32 -0.00794 -0.17 0.0233 0.0899 1662612 IFLab1_001435 O=C(COc1ccc2c3CCCc3c(=O)oc2c1)OCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B06 compound treatment 0.31 -0.0169 -0.67 0.324 -0.00394 -0.08 -0.5292 -0.7886 1730696 IFLab1_001436 CC(C)(CO)NC(=O)c1ccccc1F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B07 compound treatment 0.331 0.00406 0.16 0.328 6.25E-5 0.0 0.1139 0.7129 1373454 IFLab1_001437 CC(Oc1cc(C)cc2oc(=O)c3CCCCc3c12)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B08 compound treatment 0.335 0.00806 0.32 0.332 0.00406 0.09 0.2843 0.8661 2066375 IFLab1_001438 CC(C)CCn1c(CO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B09 compound treatment 0.385 0.0581 2.28 0.365 0.0371 0.78 2.1627 0.897 1469532 IFLab1_001439 CN(C)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B10 compound treatment 0.336 0.00906 0.36 0.332 0.00406 0.09 0.3121 0.8519 1327495 IFLab1_001440 CCn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B11 compound treatment 0.345 0.0181 0.71 0.337 0.00906 0.19 0.6363 0.8656 1278001 IFLab1_001441 Cc1c(O)c(CN2CCCC2)cc3c4CCCCc4c(=O)oc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B12 compound treatment 0.341 0.0141 0.55 0.331 0.00306 0.06 0.4363 0.7838 1002093 IFLab1_001442 CC(=O)Oc1ccc2c(C)cc(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B13 compound treatment 0.345 0.0181 0.71 0.33 0.00206 0.04 0.5327 0.7487 1675366 IFLab1_001443 CC(=C)COc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B14 compound treatment 0.342 0.0151 0.59 0.33 0.00206 0.04 0.4493 0.7566 1264606 IFLab1_001444 Cc1ccc(NC(=O)CSc2nnc(NC(=O)c3cccs3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B15 compound treatment 0.35 0.0231 0.91 0.345 0.0171 0.36 0.8937 0.917 1184152 IFLab1_001445 N#CC(=C1C=C(Oc2ccccc12)c3ccccc3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B16 compound treatment 0.319 -0.00794 -0.31 0.334 0.00606 0.13 -0.131 -0.3888 2066376 IFLab1_001446 Fc1ccccc1NC(=O)CSc2nnc(NC(=O)c3cccs3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B17 compound treatment 0.327 6.25E-5 0.0 0.342 0.0141 0.29 0.2098 0.713 2066377 IFLab1_001447 O=c1cc(oc-2c1Cc3ccccc32)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B18 compound treatment 0.342 0.0151 0.59 0.33 0.00206 0.04 0.4493 0.7566 1726638 IFLab1_001448 CCCC(=O)Nc1nnc(SCC(=O)N2CCc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B19 compound treatment 0.336 0.00906 0.36 0.301 -0.0269 -0.56 -0.1466 -0.2199 1180953 IFLab1_001449 CCN(CC)c1ccc2cc(c3nnc(o3)c4cccs4)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B20 compound treatment 0.337 0.0101 0.4 0.341 0.0131 0.27 0.473 0.9837 1721660 IFLab1_001450 CCC(=O)Nc1nnc(SCc2cccc(F)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B21 compound treatment 0.336 0.00906 0.36 0.339 0.0111 0.23 0.4156 0.9782 1403641 IFLab1_001451 O=C(N1CCc2ccccc12)c3ccc(cc3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B22 compound treatment 0.337 0.0101 0.4 0.334 0.00606 0.13 0.3695 0.8892 1575463 IFLab1_001452 CCOC(=O)CSc1nnc(NC(=O)CC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B23 mock treatment 0.337 0.0101 0.4 0.328 6.25E-5 0.0 0.2807 0.7094 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 B24 positive control 0.078 -0.249 -9.79 0.078 -0.25 -5.23 -10.6193 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C01 compound treatment 0.345 0.0181 0.71 0.346 0.0181 0.38 0.7694 0.9564 1728261 IFLab1_001453 CSc1nc2ccc(NC(=O)c3ccc(cc3)N(C)C)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C02 compound treatment 0.423 0.0961 3.78 0.437 0.109 2.28 4.2845 0.9709 2066378 IFLab1_001454 CCOc1ccc2C(=O)/C(=C\c3ccccc3O)/Sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C03 compound treatment 0.332 0.00506 0.2 0.33 0.00206 0.04 0.1713 0.8409 1133641 IFLab1_001455 COc1ccc(cc1)c2csc(NC(=O)CCOc3ccccc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C04 compound treatment 0.331 0.00406 0.16 0.347 0.0191 0.4 0.395 0.9193 2066379 IFLab1_001456 COc1cccc(c1)N2C(=O)/C(=C/c3cccc(O)c3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C05 compound treatment 0.314 -0.0129 -0.51 0.311 -0.0169 -0.35 -0.6103 -0.9844 2066380 IFLab1_001457 O=S(=O)(NCCCN1CCOCC1)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C06 compound treatment 0.338 0.0111 0.43 0.326 -0.00194 -0.04 0.2789 0.6384 2066381 IFLab1_001458 CCCCc1nnc(NC(=O)CCCN2C(=O)/C(=C/c3ccccc3)/SC2=S)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C07 compound treatment 0.343 0.0161 0.63 0.344 0.0161 0.34 0.6842 0.9564 2066382 IFLab1_001459 CC(C)N1C(=O)/C(=C\c2ccc(cc2)C(F)(F)F)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C08 compound treatment 1.127 0.8 31.46 1.073 0.745 15.59 33.2681 0.9476 2066383 IFLab1_001460 CC(N1C(=O)/C(=C\c2ccco2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C09 compound treatment 0.363 0.0361 1.42 0.362 0.0341 0.71 1.5066 0.9494 1258028 IFLab1_001461 Fc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C10 compound treatment 0.339 0.0121 0.47 0.345 0.0171 0.36 0.5878 0.9902 1469046 IFLab1_001462 CC(C)C(=O)Nc1c2CSCc2nn1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C11 compound treatment 0.328 0.00106 0.04 0.334 0.00606 0.13 0.1192 0.8928 2066384 IFLab1_001463 Cc1ccc(o1)c2nn(cc2C#N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C12 compound treatment 0.362 0.0351 1.38 0.36 0.0321 0.67 1.4492 0.9452 1320609 IFLab1_001464 CC(C)(C)n1nc2CSCc2c1NC(=O)COc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C13 compound treatment 0.458 0.131 5.15 0.457 0.129 2.7 5.5536 0.9546 1922484 IFLab1_001465 OC(=O)CN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C14 compound treatment 0.33 0.00306 0.12 0.343 0.0151 0.32 0.308 0.9129 1454292 IFLab1_001466 COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C15 compound treatment 0.334 0.00706 0.28 0.336 0.00806 0.17 0.3157 0.9715 2066385 IFLab1_001467 COc1ccccc1/C=C\2/SC(=O)N(CCC(=O)Nc3ccccc3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C16 compound treatment 0.348 0.0211 0.83 0.359 0.0311 0.65 1.0452 0.9928 1301535 IFLab1_001468 Clc1ccc(COc2ccc3ccc(=O)oc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C17 compound treatment 0.48 0.153 6.02 0.462 0.134 2.81 6.2392 0.9397 2066386 IFLab1_001469 CCN(CC)C(=O)CCCN1C(=O)/C(=C/c2ccc(OC)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C18 compound treatment 0.327 6.25E-5 0.0 0.343 0.0151 0.32 0.2246 0.7126 1329720 IFLab1_001470 Cc1cc(=O)oc2cc(OCC(=O)N)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C19 compound treatment 0.783 0.456 17.93 0.735 0.407 8.52 18.7028 0.9421 2066387 IFLab1_001471 CCCC(N1C(=O)/C(=C/c2ccc(C)cc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C20 compound treatment 0.321 -0.00594 -0.23 0.328 6.25E-5 0.0 -0.1641 -0.7031 2066388 IFLab1_001472 CCCc1cc(=O)oc2cc(OCC)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C21 compound treatment 0.337 0.0101 0.4 0.341 0.0131 0.27 0.473 0.9837 1207391 IFLab1_001473 Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C22 compound treatment 0.337 0.0101 0.4 0.339 0.0111 0.23 0.4435 0.9674 1609929 IFLab1_001474 CCOc1ccc2c(cc(=O)oc2c1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C23 mock treatment 0.327 6.25E-5 0.0 0.334 0.00606 0.13 0.0914 0.7207 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 C24 positive control 0.079 -0.248 -9.75 0.079 -0.249 -5.21 -10.5767 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D01 compound treatment 0.342 0.0151 0.59 0.351 0.0231 0.48 0.76 0.9948 1275473 IFLab1_001475 COC(=O)COc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D02 compound treatment 0.331 0.00406 0.16 0.333 0.00506 0.11 0.1879 0.9801 1507053 IFLab1_001476 Clc1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D03 compound treatment 0.334 0.00706 0.28 0.331 0.00306 0.06 0.2417 0.848 1548289 IFLab1_001477 CC(=O)Oc1cc(OC(=O)C)c2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D04 compound treatment 0.338 0.0111 0.43 0.335 0.00706 0.15 0.4121 0.897 1731317 IFLab1_001478 Brc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D05 compound treatment 0.333 0.00606 0.24 0.333 0.00506 0.11 0.2435 0.9333 1184556 IFLab1_001479 CCOC(=O)C(C)Oc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D06 compound treatment 0.343 0.0161 0.63 0.335 0.00706 0.15 0.5511 0.8496 1549066 IFLab1_001480 CC(C)(CO)NC(=O)c1ccc(Cl)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D07 compound treatment 0.341 0.0141 0.55 0.342 0.0141 0.29 0.5991 0.9564 1407462 IFLab1_001481 Cc1cc(OCC(=O)N)c2c3CCCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D08 compound treatment 0.342 0.0151 0.59 0.335 0.00706 0.15 0.5233 0.8573 2066389 IFLab1_001482 CCCn1c(CO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D09 compound treatment 0.35 0.0231 0.91 0.35 0.0221 0.46 0.9676 0.951 1222573 IFLab1_001483 CN1CCN(Cc2c(O)ccc3c(cc(=O)oc23)c4ccccc4)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D10 compound treatment 0.317 -0.00994 -0.39 0.324 -0.00394 -0.08 -0.3345 -0.8378 2066390 IFLab1_001484 CC(C)n1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D11 compound treatment 0.366 0.0391 1.54 0.37 0.0421 0.88 1.7084 0.9651 1596779 IFLab1_001485 Cc1c(O)c(CN2CCOCC2)cc3c(cc(=O)oc13)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D12 compound treatment 0.346 0.0191 0.75 0.341 0.0131 0.27 0.7233 0.9066 1247768 IFLab1_001486 CC(=O)Nc1nnc(SCC(=O)Nc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D13 compound treatment 0.349 0.0221 0.87 0.325 -0.00294 -0.06 0.5699 0.6554 1379272 IFLab1_001487 O=C(COc1ccc2c3CCCc3c(=O)oc2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D14 compound treatment 0.359 0.0321 1.26 0.36 0.0321 0.67 1.3658 0.9564 1659161 IFLab1_001488 Cc1ccc(NC(=O)CSc2nnc(NC(=O)C3CCCCC3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D15 compound treatment 0.341 0.0141 0.55 0.33 0.00206 0.04 0.4215 0.76 1413686 IFLab1_001489 N#CC(=C1C=C(Sc2ccccc12)c3ccccc3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D16 compound treatment 0.334 0.00706 0.28 0.334 0.00606 0.13 0.2861 0.937 2066391 IFLab1_001490 CC(C)(C)C(=O)Nc1nnc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D17 compound treatment 0.336 0.00906 0.36 0.335 0.00706 0.15 0.3565 0.9241 1685836 IFLab1_001491 c1cnc2ccc(cc2c1)c3ccc4ncccc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D18 compound treatment 0.341 0.0141 0.55 0.335 0.00706 0.15 0.4955 0.8657 1651045 IFLab1_001492 O=C(CSc1nnc(NC(=O)C2CCCCC2)s1)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D19 compound treatment 0.34 0.0131 0.51 0.338 0.0101 0.21 0.5121 0.9225 2066392 IFLab1_001493 OC(=O)c1cc(=O)[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D20 compound treatment 0.336 0.00906 0.36 0.335 0.00706 0.15 0.3565 0.9241 1332183 IFLab1_001494 CC(C)C(=O)Nc1nnc(SCc2cccc(F)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D21 compound treatment 0.332 0.00506 0.2 0.341 0.0131 0.27 0.334 0.9879 1205400 IFLab1_001495 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D22 compound treatment 0.34 0.0131 0.51 0.338 0.0101 0.21 0.5121 0.9225 1310468 IFLab1_001496 CCOC(=O)CSc1nnc(NC(=O)C(C)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D23 mock treatment 0.33 0.00306 0.12 0.325 -0.00294 -0.06 0.0417 0.3083 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 D24 positive control 0.08 -0.247 -9.71 0.08 -0.248 -5.19 -10.5341 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E01 compound treatment 0.391 0.0641 2.52 0.403 0.0751 1.57 2.8918 0.9742 1152420 IFLab1_001497 CN(C)c1ccc(cc1)C(=O)Nc2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E02 compound treatment 0.325 -0.00194 -0.08 0.328 6.25E-5 0.0 -0.0529 -0.6949 2066393 IFLab1_001498 Fc1ccccc1OCC(=O)Nc2cc(ccc2Cl)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E03 compound treatment 0.329 0.00206 0.08 0.331 0.00306 0.06 0.1027 0.9932 1125027 IFLab1_001499 Cc1cc(NC(=O)CCOc2ccccc2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E04 compound treatment 0.275 -0.0519 -2.04 0.259 -0.0689 -1.44 -2.464 -0.9855 2066394 IFLab1_001500 COc1cccc(c1)N2C(=O)/C(=C/c3ccco3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E05 compound treatment 0.338 0.0111 0.43 0.334 0.00606 0.13 0.3973 0.8768 1350022 IFLab1_001501 Fc1ccc(cc1)C(=O)N2CCCC3C=CC=CC32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E06 compound treatment 0.338 0.0111 0.43 0.335 0.00706 0.15 0.4121 0.897 2066395 IFLab1_001502 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(C)cc3)C2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E07 compound treatment 0.341 0.0141 0.55 0.343 0.0151 0.32 0.6138 0.9645 2066396 IFLab1_001503 Clc1c(CSc2nncn2c3ccccc3)nc4ncccn14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E08 compound treatment 0.588 0.261 10.26 0.561 0.233 4.88 10.7067 0.9421 2066397 IFLab1_001504 CC(N1C(=O)/C(=C\c2ccc(Br)cc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E09 compound treatment 0.35 0.0231 0.91 0.345 0.0171 0.36 0.8937 0.917 2066398 IFLab1_001505 CC(=O)NC1=NC(=O)CS1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E10 compound treatment 0.346 0.0191 0.75 0.351 0.0231 0.48 0.8712 0.9773 1210816 IFLab1_001506 CC(C)(C)n1nc2CSCc2c1NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E11 compound treatment 0.356 0.0291 1.14 0.36 0.0321 0.67 1.2824 0.9678 2066399 IFLab1_001507 O=c1oc2ccccc2cc1c3nn(cc3C#N)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E12 compound treatment 0.377 0.0501 1.97 0.38 0.0521 1.09 2.1622 0.9611 1584875 IFLab1_001508 CCCC(=O)Nc1c2CSCc2nn1c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E13 compound treatment 0.49 0.163 6.41 0.485 0.157 3.29 6.8575 0.9518 1913451 IFLab1_001509 OC(=O)CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E14 compound treatment 0.318 -0.00894 -0.35 0.318 -0.00994 -0.21 -0.3955 -0.9687 1289218 IFLab1_001510 CCCOc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E15 compound treatment 0.377 0.0501 1.97 0.379 0.0511 1.07 2.1474 0.9588 2066400 IFLab1_001511 CCOC(=O)CCCN1C(=O)/C(=C/c2ccc(OC)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E16 compound treatment 0.334 0.00706 0.28 0.345 0.0171 0.36 0.4488 0.9923 1682566 IFLab1_001512 Cc1cccc(COc2ccc3ccc(=O)oc3c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E17 compound treatment 0.714 0.387 15.22 0.712 0.384 8.04 16.4441 0.9555 2066401 IFLab1_001513 Cc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E18 compound treatment 0.342 0.0151 0.59 0.34 0.0121 0.25 0.5973 0.9277 1411884 IFLab1_001514 CCOc1cc2oc(=O)cc(C)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E19 compound treatment 0.666 0.339 13.33 0.653 0.325 6.8 14.2366 0.9512 2066402 IFLab1_001515 CCOc1cc(/C=C/2\SC(=S)N(C(C(C)C)C(=O)O)C2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E20 compound treatment 0.319 -0.00794 -0.31 0.323 -0.00494 -0.1 -0.2937 -0.8935 1476798 IFLab1_001516 CCCc1cc(=O)oc2cc(OCC(=O)O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E21 compound treatment 0.34 0.0131 0.51 0.34 0.0121 0.25 0.5417 0.9465 1428720 IFLab1_001517 OCCN1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E22 compound treatment 0.375 0.0481 1.89 0.36 0.0321 0.67 1.8107 0.9029 1122185 IFLab1_001518 CCc1cc2c(cc(=O)oc2cc1O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E23 mock treatment 0.304 -0.0229 -0.9 0.329 0.00106 0.02 -0.622 -0.6895 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 E24 positive control 0.081 -0.246 -9.67 0.081 -0.247 -5.17 -10.4915 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F01 compound treatment 0.332 0.00506 0.2 0.352 0.0241 0.5 0.4968 0.9175 1303820 IFLab1_001519 CCOC(=O)COc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F02 compound treatment 0.325 -0.00194 -0.08 0.327 -9.37E-4 -0.02 -0.0677 -0.8611 1326772 IFLab1_001520 COc1ccccc1NC(=O)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F03 compound treatment 0.331 0.00406 0.16 0.34 0.0121 0.25 0.2914 0.9756 1206227 IFLab1_001521 COc1cc(OC)c2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F04 compound treatment 0.329 0.00206 0.08 0.337 0.00906 0.19 0.1914 0.9282 1464242 IFLab1_001522 O=C(N1CCc2ccccc12)c3cc(=O)c4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F05 compound treatment 0.324 -0.00294 -0.12 0.324 -0.00394 -0.08 -0.1399 -0.9863 1225694 IFLab1_001523 CC(Oc1ccc2c3CCCc3c(=O)oc2c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F06 compound treatment 0.328 0.00106 0.04 0.332 0.00406 0.09 0.0897 0.9465 1584088 IFLab1_001524 CC(C)(CO)NC(=O)C(c1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F07 compound treatment 0.332 0.00506 0.2 0.347 0.0191 0.4 0.4228 0.9484 1220389 IFLab1_001525 COc1cc(OC)c2c3CCCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F08 compound treatment 0.338 0.0111 0.43 0.335 0.00706 0.15 0.4121 0.897 2066403 IFLab1_001526 OCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F09 compound treatment 0.348 0.0211 0.83 0.36 0.0321 0.67 1.06 0.9945 1176846 IFLab1_001527 Oc1ccc2c(cc(=O)oc2c1CN3CCOCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F10 compound treatment 0.343 0.0161 0.63 0.346 0.0181 0.38 0.7138 0.9699 2066404 IFLab1_001528 Cn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F11 compound treatment 0.419 0.0921 3.62 0.462 0.134 2.81 4.5433 0.9921 1208562 IFLab1_001529 CCN(CC)Cc1cc2c(cc(=O)oc2c(C)c1O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F12 compound treatment 0.349 0.0221 0.87 0.347 0.0191 0.4 0.8955 0.9379 1287153 IFLab1_001530 CCC(=O)Nc1nnc(SCC(=O)Nc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F13 compound treatment 0.374 0.0471 1.85 0.392 0.0641 1.34 2.2564 0.9875 1590271 IFLab1_001531 CC1=CC(C=C(O1)c2ccccc2)C(C#N)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F14 compound treatment 0.323 -0.00394 -0.15 0.354 0.0261 0.55 0.2762 0.4871 1707654 IFLab1_001532 Cc1ccc(C)c(NC(=O)CSc2nnc(NC(=O)c3ccccc3F)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F15 compound treatment 0.369 0.0421 1.65 0.371 0.0431 0.9 1.8066 0.9592 2066405 IFLab1_001533 CCCC[n+]1c(C)sc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F16 compound treatment 0.324 -0.00294 -0.12 0.332 0.00406 0.09 -0.0216 -0.1503 2066406 IFLab1_001534 CCCC(=O)Nc1nnc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F17 compound treatment 0.334 0.00706 0.28 0.345 0.0171 0.36 0.4488 0.9923 1592207 IFLab1_001535 CCOCC(=O)NC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F18 compound treatment 0.34 0.0131 0.51 0.355 0.0271 0.57 0.7636 0.9988 1686691 IFLab1_001536 O=C(CSc1nnc(NC(=O)c2ccccc2)s1)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F19 compound treatment 0.502 0.175 6.88 0.509 0.181 3.79 7.5463 0.9604 1559933 IFLab1_001537 Oc1ccc2cc(C(=O)Nc3ccc(F)cc3)c(=N)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F20 compound treatment 0.346 0.0191 0.75 0.345 0.0171 0.36 0.7825 0.9425 1507214 IFLab1_001538 Fc1cccc(CSc2nnc(NC(=O)COc3ccccc3)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F21 compound treatment 0.34 0.0131 0.51 0.33 0.00206 0.04 0.3937 0.7638 1148185 IFLab1_001539 O=C(N1CCc2ccccc2C1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F22 compound treatment 0.318 -0.00894 -0.35 0.343 0.0151 0.32 -0.0256 -0.0542 1244303 IFLab1_001540 CCOC(=O)CSc1nnc(NC(=O)C2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F23 mock treatment 0.328 0.00106 0.04 0.315 -0.0129 -0.27 -0.1619 -0.591 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 F24 positive control 0.081 -0.246 -9.67 0.081 -0.247 -5.17 -10.4915 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G01 compound treatment 0.338 0.0111 0.43 0.348 0.0201 0.42 0.6044 0.9998 1682851 IFLab1_001541 CN(C)c1ccc(cc1)C(=O)Nc2cc(C)on2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G02 compound treatment 0.317 -0.00994 -0.39 0.332 0.00406 0.09 -0.2162 -0.5406 2066407 IFLab1_001542 CC(N)(C(=O)O)c1cccc(OCc2ccccc2F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G03 compound treatment 0.357 0.0301 1.18 0.362 0.0341 0.71 1.3398 0.9707 1599345 IFLab1_001543 NC(=O)c1c(NC(=O)CCOc2ccccc2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G04 compound treatment 0.344 0.0171 0.67 0.341 0.0131 0.27 0.6677 0.9217 2066408 IFLab1_001544 COC(=O)c1ccc(/C=C/2\SC(=S)N(C2=O)c3cccc(OC)c3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G05 compound treatment 0.323 -0.00394 -0.15 0.32 -0.00794 -0.17 -0.2269 -0.9994 1224648 IFLab1_001545 O=C(N1CCN(Cc2ccccc2)CC1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G06 compound treatment 0.335 0.00806 0.32 0.33 0.00206 0.04 0.2547 0.796 2066409 IFLab1_001546 Oc1ccc(cc1)N2C(=O)S/C(=C\c3ccccc3)/C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G07 compound treatment 0.337 0.0101 0.4 0.334 0.00606 0.13 0.3695 0.8892 1557893 IFLab1_001547 O=C(Nc1nc(cs1)c2ccccc2)C3CCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G08 compound treatment 0.654 0.327 12.86 0.603 0.275 5.76 13.1631 0.9343 2066410 IFLab1_001548 Cc1ccc(/C=C/2\SC(=S)N(C(CCC(=O)O)C(=O)O)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G09 compound treatment 0.342 0.0151 0.59 0.346 0.0181 0.38 0.686 0.9765 2066411 IFLab1_001549 O=C(NC1=NC(=O)CS1)C2CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G10 compound treatment 0.361 0.0341 1.34 0.352 0.0241 0.5 1.3031 0.9107 1332028 IFLab1_001550 O=C(Nc1c2CSCc2nn1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G11 compound treatment 0.346 0.0191 0.75 0.35 0.0221 0.46 0.8564 0.9729 2066412 IFLab1_001551 N#Cc1cn(nc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G12 compound treatment 0.344 0.0171 0.67 0.333 0.00506 0.11 0.5493 0.8087 2066413 IFLab1_001552 CCC(CC)C(=O)Nc1c2CSCc2nn1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G13 compound treatment 0.512 0.185 7.28 0.487 0.159 3.33 7.4988 0.9372 2066414 IFLab1_001553 CC(C)C(N1C(=O)/C(=C\2/C(=O)Nc3ccccc23)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G14 compound treatment 0.327 6.25E-5 0.0 0.328 6.25E-5 0.0 0.0027 0.9564 1337075 IFLab1_001554 COC(=O)COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G15 compound treatment 0.37 0.0431 1.69 0.372 0.0441 0.92 1.8492 0.9592 2066415 IFLab1_001555 CN1CCN(CC1)C(=O)CN2C(=O)/C(=C/c3ccc(C)cc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G16 compound treatment 0.339 0.0121 0.47 0.338 0.0101 0.21 0.4843 0.9332 1232944 IFLab1_001556 Cc1ccc(COc2ccc3ccc(=O)oc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G17 compound treatment 0.316 -0.0109 -0.43 0.334 0.00606 0.13 -0.2144 -0.4781 2066416 IFLab1_001557 OC(=O)CN1C(=O)S/C(=C\c2ccccc2Cl)/C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G18 compound treatment 0.335 0.00806 0.32 0.329 0.00106 0.02 0.2399 0.7548 1653969 IFLab1_001558 COC(=O)COc1cc2oc(=O)cc(C)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G19 compound treatment 0.842 0.515 20.25 0.793 0.465 9.73 21.2014 0.9436 2066417 IFLab1_001559 CCOc1cc(/C=C/2\SC(=S)N(C(C)C(=O)O)C2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G20 compound treatment 0.319 -0.00794 -0.31 0.319 -0.00894 -0.19 -0.3529 -0.97 1702937 IFLab1_001560 CCCOc1ccc2c(C)c(CCC)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G21 compound treatment 0.392 0.0651 2.56 0.389 0.0611 1.28 2.7124 0.9486 2066418 IFLab1_001561 CC1=CC(=O)/C(=C\c2c(O)cc(C)oc2=O)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G22 compound treatment 0.312 -0.0149 -0.59 0.316 -0.0119 -0.25 -0.5919 -0.9275 1172857 IFLab1_001562 CCCc1cc2c(cc(=O)oc2cc1OC(=O)C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G23 mock treatment 0.32 -0.00694 -0.27 0.319 -0.00894 -0.19 -0.3251 -0.9831 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 G24 positive control 0.081 -0.246 -9.67 0.08 -0.248 -5.19 -10.5063 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H01 compound treatment 0.344 0.0171 0.67 0.342 0.0141 0.29 0.6825 0.9316 1534948 IFLab1_001563 CCOC(=O)C(C)Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H02 compound treatment 0.328 0.00106 0.04 0.341 0.0131 0.27 0.2228 0.8058 1297509 IFLab1_001564 COc1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H03 compound treatment 0.327 6.25E-5 0.0 0.327 -9.37E-4 -0.02 -0.0121 -0.6137 1220421 IFLab1_001565 CCOc1cc(OCC)c2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H04 compound treatment 0.328 0.00106 0.04 0.329 0.00106 0.02 0.0453 0.9564 1413645 IFLab1_001566 CC(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H05 compound treatment 0.33 0.00306 0.12 0.333 0.00506 0.11 0.1601 0.998 1632768 IFLab1_001567 O=c1oc2cc(OCc3ccccc3)ccc2c4CCCc41 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H06 compound treatment 0.331 0.00406 0.16 0.321 -0.00694 -0.15 0.0103 0.0477 2066419 IFLab1_001568 CCCn1c(CC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H07 compound treatment 0.35 0.0231 0.91 0.358 0.0301 0.63 1.086 0.984 2066420 IFLab1_001569 CCC(NCc1c(O)ccc2c3CCCc3c(=O)oc12)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H08 compound treatment 0.337 0.0101 0.4 0.337 0.00906 0.19 0.4139 0.9433 2066421 IFLab1_001570 CC(C)Cn1c(CO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H09 compound treatment 0.346 0.0191 0.75 0.343 0.0151 0.32 0.7529 0.9259 1583196 IFLab1_001571 CN1CCN(Cc2c(O)cc(C)c3c4ccccc4c(=O)oc23)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H10 compound treatment 0.344 0.0171 0.67 0.342 0.0141 0.29 0.6825 0.9316 2066422 IFLab1_001572 CC(C)n1c(CO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H11 compound treatment 0.347 0.0201 0.79 0.342 0.0141 0.29 0.7659 0.9097 1588833 IFLab1_001573 Cc1cc2oc(=O)cc(c3ccccc3)c2c(O)c1CN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H12 compound treatment 0.343 0.0161 0.63 0.338 0.0101 0.21 0.5955 0.8945 1590861 IFLab1_001574 CC(C)C(=O)Nc1nnc(SCC(=O)Nc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H13 compound treatment 0.354 0.0271 1.06 0.355 0.0271 0.57 1.1528 0.9564 1060778 IFLab1_001575 O=C(CC(C1CCCCC1=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H14 compound treatment 0.334 0.00706 0.28 0.332 0.00406 0.09 0.2565 0.8831 1392262 IFLab1_001576 CCCC(=O)Nc1nnc(SCC(=O)Nc2ccc(C)cc2C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H15 compound treatment 0.318 -0.00894 -0.35 0.317 -0.0109 -0.23 -0.4103 -0.9784 2066423 IFLab1_001577 CC(C)(C)c1ccc2ccccc2[o+]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H16 compound treatment 0.34 0.0131 0.51 0.337 0.00906 0.19 0.4973 0.9083 1536325 IFLab1_001578 Cc1ccc(cc1)C(=O)Nc2nnc(SCC(=O)N3CCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H17 compound treatment 0.34 0.0131 0.51 0.338 0.0101 0.21 0.5121 0.9225 1514764 IFLab1_001579 COC(=O)c1cc(Br)ccc1OC(=O)c2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H18 compound treatment 0.358 0.0311 1.22 0.329 0.00106 0.02 0.8793 0.7199 2066424 IFLab1_001580 CC(=O)Nc1nnc(SCc2ccc(cc2)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H19 compound treatment 0.332 0.00506 0.2 0.327 -9.37E-4 -0.02 0.1269 0.6343 2066425 IFLab1_001581 CCCOC(=O)c1ccc(NC(=O)C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H20 compound treatment 0.359 0.0321 1.26 0.355 0.0271 0.57 1.2918 0.9348 1426131 IFLab1_001582 Fc1cccc(CSc2nnc(NC(=O)Cc3ccccc3)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H21 compound treatment 0.321 -0.00594 -0.23 0.338 0.0101 0.21 -0.0162 -0.0515 1540083 IFLab1_001583 O=C(N1CCc2ccccc2C1)c3ccc(cc3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H22 compound treatment 0.338 0.0111 0.43 0.335 0.00706 0.15 0.4121 0.897 1462660 IFLab1_001584 CCOC(=O)CSc1nnc(NC(=O)C2CCCCC2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H23 mock treatment 0.333 0.00606 0.24 0.327 -9.37E-4 -0.02 0.1547 0.6467 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 H24 positive control 0.083 -0.244 -9.59 0.082 -0.246 -5.15 -10.4211 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I01 compound treatment 0.397 0.0701 2.75 0.362 0.0341 0.71 2.4519 0.8617 1191498 IFLab1_001585 Brc1ccc2nc(NC(=O)CCOc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I02 compound treatment 0.33 0.00306 0.12 0.344 0.0161 0.34 0.3228 0.9042 1337876 IFLab1_001586 NC(=O)c1cc(Br)c(O)c(Br)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I03 compound treatment 0.344 0.0171 0.67 0.347 0.0191 0.4 0.7564 0.9692 1403897 IFLab1_001587 Cc1csc(NC(=O)CCCC(=O)O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I04 compound treatment 0.361 0.0341 1.34 0.362 0.0341 0.71 1.451 0.9564 2066426 IFLab1_001588 CCN(CC)c1ccc(cc1)N2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I05 compound treatment 0.304 -0.0229 -0.9 0.303 -0.0249 -0.52 -1.0067 -0.9662 2066427 IFLab1_001589 CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I06 compound treatment 0.385 0.0581 2.28 0.413 0.0851 1.78 2.8729 0.9924 2066428 IFLab1_001590 Oc1ccc(/N=C/2\S/C(=C\c3ccccc3)/C(=O)N2c4ccc(O)cc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I07 compound treatment 0.342 0.0151 0.59 0.35 0.0221 0.46 0.7452 0.9924 1519257 IFLab1_001591 Cc1ccc(cc1)S(=O)(=O)NC(CC(=O)O)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I08 compound treatment 0.679 0.352 13.84 0.655 0.327 6.84 14.6276 0.9473 2066429 IFLab1_001592 CC(N1C(=O)/C(=C/c2cccc3ccccc23)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I09 compound treatment 0.345 0.0181 0.71 0.343 0.0151 0.32 0.7251 0.9332 1918681 IFLab1_001593 OC(=O)c1cn(nc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I10 compound treatment 0.37 0.0431 1.69 0.379 0.0511 1.07 1.9528 0.9754 2066430 IFLab1_001594 O=C(Nc1c2CSCc2nn1c3ccccc3)/C=C/c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I11 compound treatment 0.355 0.0281 1.1 0.36 0.0321 0.67 1.2546 0.9716 2066431 IFLab1_001595 CCc1ccc(cc1)c2nn(cc2C#N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I12 compound treatment 0.381 0.0541 2.13 0.36 0.0321 0.67 1.9775 0.8872 2066432 IFLab1_001596 CC(C)CC(=O)Nc1c2CSCc2nn1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I13 compound treatment 0.564 0.237 9.32 0.525 0.197 4.12 9.5068 0.9327 1916983 IFLab1_001597 CC(C)C(N1C(=O)/C(=C/c2ccccc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I14 compound treatment 0.324 -0.00294 -0.12 0.341 0.0131 0.27 0.1116 0.3761 1176011 IFLab1_001598 OC(=O)COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I15 compound treatment 0.382 0.0551 2.16 0.361 0.0331 0.69 2.0201 0.8888 2066433 IFLab1_001599 Oc1ccccc1NC(=O)CCCN2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I16 compound treatment 0.337 0.0101 0.4 0.339 0.0111 0.23 0.4435 0.9674 1641566 IFLab1_001600 CCOC(=O)COc1ccc2ccc(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I17 compound treatment 0.543 0.216 8.5 0.515 0.187 3.91 8.775 0.9381 2066434 IFLab1_001601 CCC(N1C(=O)/C(=C/c2ccccc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I18 compound treatment 0.351 0.0241 0.95 0.336 0.00806 0.17 0.7883 0.8203 1136950 IFLab1_001602 CCOC(=O)COc1cc2oc(=O)cc(C)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I19 compound treatment 0.359 0.0321 1.26 0.368 0.0401 0.84 1.4842 0.9804 2066435 IFLab1_001603 O=C(CCN1C(=O)/C(=C/c2ccccc2)/SC1=S)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I20 compound treatment 0.343 0.0161 0.63 0.337 0.00906 0.19 0.5807 0.8806 1634155 IFLab1_001604 CCCc1c(C)c2ccc(OCC(=O)OC)cc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I21 compound treatment 0.342 0.0151 0.59 0.331 0.00306 0.06 0.4641 0.7791 1631732 IFLab1_001605 Oc1c(CN2CCc3ccccc3C2)cc(Cl)c4cccnc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I22 compound treatment 0.392 0.0651 2.56 0.377 0.0491 1.03 2.5349 0.9196 1657318 IFLab1_001606 CCCc1cc2c(cc(=O)oc2cc1O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I23 mock treatment 0.309 -0.0179 -0.71 0.308 -0.0199 -0.42 -0.7937 -0.9686 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 I24 positive control 0.084 -0.243 -9.55 0.083 -0.245 -5.13 -10.3785 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J01 compound treatment 0.352 0.0251 0.99 0.342 0.0141 0.29 0.9049 0.8799 1497163 IFLab1_001607 Cc1cc(O)c2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J02 compound treatment 0.373 0.0461 1.81 0.364 0.0361 0.75 1.8143 0.9247 1339908 IFLab1_001608 COc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J03 compound treatment 0.333 0.00606 0.24 0.336 0.00806 0.17 0.2879 0.9857 1456924 IFLab1_001609 CCOc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J04 compound treatment 0.33 0.00306 0.12 0.331 0.00306 0.06 0.1305 0.9564 2066436 IFLab1_001610 COC(=O)c1ccc(Cl)c(N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J05 compound treatment 0.328 0.00106 0.04 0.331 0.00306 0.06 0.0749 0.9785 1269936 IFLab1_001611 COc1cc2oc(=O)c3CCCc3c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J06 compound treatment 0.328 0.00106 0.04 0.325 -0.00294 -0.06 -0.0139 -0.1874 2066437 IFLab1_001612 C(Cn1cnc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J07 compound treatment 0.342 0.0151 0.59 0.34 0.0121 0.25 0.5973 0.9277 1348555 IFLab1_001613 CCCc1cc(=O)oc2c(CN3CCCCC3)c(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J08 compound treatment 0.322 -0.00494 -0.19 0.333 0.00506 0.11 -0.0624 -0.282 1316654 IFLab1_001614 OCc1nc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J09 compound treatment 0.365 0.0381 1.5 0.346 0.0181 0.38 1.3255 0.8587 1437457 IFLab1_001615 CCC1CCCCN1Cc2c(O)cc(C)c3c4ccccc4c(=O)oc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J10 compound treatment 0.338 0.0111 0.43 0.338 0.0101 0.21 0.4565 0.9446 2066438 IFLab1_001616 Fc1c(F)c(F)c(c(F)c1F)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J11 compound treatment 0.355 0.0281 1.1 0.356 0.0281 0.59 1.1954 0.9564 1552348 IFLab1_001617 COC(=O)c1ccc(Oc2coc3cc(OC)ccc3c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J12 compound treatment 0.373 0.0461 1.81 0.376 0.0481 1.01 1.9918 0.9615 1577132 IFLab1_001618 O=C(CSc1nnc(NC(=O)Cc2ccccc2)s1)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J13 compound treatment 0.343 0.0161 0.63 0.336 0.00806 0.17 0.5659 0.8657 1667612 IFLab1_001619 Cc1cc(O)c(C(=O)c2ccccc2)c(=O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J14 compound treatment 0.352 0.0251 0.99 0.355 0.0271 0.57 1.0972 0.9654 1605777 IFLab1_001620 CC(C)C(=O)Nc1nnc(SCC(=O)Nc2cc(C)cc(C)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J15 compound treatment 0.856 0.529 20.8 0.776 0.448 9.38 21.339 0.9352 2066439 IFLab1_001621 Nc1ccc2C(=O)/C(=C/c3ccco3)/Cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J16 compound treatment 0.345 0.0181 0.71 0.347 0.0191 0.4 0.7842 0.9628 1258313 IFLab1_001622 CC(C)C(=O)Nc1nnc(SCC(=O)N2CCCc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J17 compound treatment 0.343 0.0161 0.63 0.343 0.0151 0.32 0.6695 0.9485 1295217 IFLab1_001623 CCOC(=O)c1cccc(n1)C(=O)Oc2ccc3cc(Br)ccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J18 compound treatment 0.347 0.0201 0.79 0.336 0.00806 0.17 0.6771 0.8394 2066440 IFLab1_001624 CCC(=O)Nc1nnc(SCc2ccc(cc2)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J19 compound treatment 0.36 0.0331 1.3 0.37 0.0421 0.88 1.5416 0.982 2066441 IFLab1_001625 Fc1ccc2nc(NC(=O)c3ccccc3Br)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J20 compound treatment 0.375 0.0481 1.89 0.371 0.0431 0.9 1.9734 0.9426 1180168 IFLab1_001626 Fc1cccc(CSc2nnc(NC(=O)C3CCCCC3)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J21 compound treatment 0.341 0.0141 0.55 0.349 0.0211 0.44 0.7026 0.9937 1724026 IFLab1_001627 CC1CC(C)CN(C1)C(=O)c2ccc(C#N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J22 compound treatment 0.336 0.00906 0.36 0.345 0.0171 0.36 0.5044 1.0 1141491 IFLab1_001628 CCOC(=O)CSc1nnc(NC(=O)c2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J23 mock treatment 0.328 0.00106 0.04 0.325 -0.00294 -0.06 -0.0139 -0.1874 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 J24 positive control 0.085 -0.242 -9.51 0.083 -0.245 -5.13 -10.3507 -0.9579 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K01 compound treatment 0.354 0.0271 1.06 0.371 0.0431 0.9 1.3896 0.9966 1200027 IFLab1_001629 CC1(C)CC(=O)c2sc(NC(=O)CCOc3ccccc3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K02 compound treatment 0.326 -9.37E-4 -0.04 0.332 0.00406 0.09 0.034 0.3675 2066442 IFLab1_001630 COC(=O)c1cc(Br)c(O)c(Br)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K03 compound treatment 0.33 0.00306 0.12 0.346 0.0181 0.38 0.3524 0.8884 2066443 IFLab1_001631 Clc1cccc(Cl)c1C(=O)n2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K04 compound treatment 0.43 0.103 4.05 0.409 0.0811 1.7 4.0648 0.9253 2066444 IFLab1_001632 Cc1cccc(N2C(=O)/C(=C/c3ccc(O)c(O)c3)/SC2=S)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K05 compound treatment 0.338 0.0111 0.43 0.337 0.00906 0.19 0.4417 0.9308 2066445 IFLab1_001633 CCN1C(=O)/C(=C/c2cccc(OC)c2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K06 compound treatment 0.364 0.0371 1.46 0.363 0.0351 0.73 1.5492 0.9496 2066446 IFLab1_001634 CC(C)(C)NC(=O)CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K07 compound treatment 0.358 0.0311 1.22 0.345 0.0171 0.36 1.1161 0.8771 1472427 IFLab1_001635 O=C(Nc1nc2sc3CCCCc3c2c(=O)s1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K08 compound treatment 0.34 0.0131 0.51 0.35 0.0221 0.46 0.6896 0.9986 1148757 IFLab1_001636 Clc1ccc2c(c1)c(nc3nnnn32)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K09 compound treatment 0.306 -0.0209 -0.82 0.293 -0.0349 -0.73 -1.0991 -0.9982 2066447 IFLab1_001637 CCN1C(=O)/C(=C/c2cn(CCC#N)nc2c3ccc(F)cc3)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K10 compound treatment 0.374 0.0471 1.85 0.371 0.0431 0.9 1.9456 0.9453 1492715 IFLab1_001638 O=C(Cc1ccccc1)Nc2c3CSCc3nn2c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K11 compound treatment 0.336 0.00906 0.36 0.351 0.0231 0.48 0.5932 0.9889 2066448 IFLab1_001639 N#CCCn1cc(C#N)c(n1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K12 compound treatment 0.38 0.0531 2.09 0.367 0.0391 0.82 2.0533 0.9163 2066449 IFLab1_001640 O=C(Nc1c2CSCc2nn1c3ccccc3)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K13 compound treatment 0.364 0.0371 1.46 0.366 0.0381 0.8 1.5936 0.9596 2066450 IFLab1_001641 COc1ccccc1/C=C/2\SC(=O)N(CCC(=O)O)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K14 compound treatment 0.345 0.0181 0.71 0.347 0.0191 0.4 0.7842 0.9628 1364279 IFLab1_001642 COC(=O)C(C)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K15 compound treatment 0.533 0.206 8.1 0.507 0.179 3.75 8.3786 0.9386 2066451 IFLab1_001643 OC(=O)c1ccc(NC(=O)CCCN2C(=O)/C(=C/c3ccccc3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K16 compound treatment 0.344 0.0171 0.67 0.334 0.00606 0.13 0.5641 0.8262 1703933 IFLab1_001644 CCOC(=O)C(C)Oc1ccc2ccc(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K17 compound treatment 0.459 0.132 5.19 0.455 0.127 2.66 5.5518 0.9517 2066452 IFLab1_001645 CC(N1C(=O)/C(=C/c2ccccc2Cl)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K18 compound treatment 0.339 0.0121 0.47 0.338 0.0101 0.21 0.4843 0.9332 1602155 IFLab1_001646 Cc1cc(=O)oc2cc(OCC(=O)O)c(Cl)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K19 compound treatment 0.357 0.0301 1.18 0.357 0.0291 0.61 1.2658 0.9523 2066453 IFLab1_001647 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K20 compound treatment 0.347 0.0201 0.79 0.345 0.0171 0.36 0.8103 0.9358 1677944 IFLab1_001648 CCCc1c(C)c2ccc(OCC(=O)O)cc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K21 compound treatment 0.331 0.00406 0.16 0.351 0.0231 0.48 0.4542 0.8935 1482253 IFLab1_001649 Oc1c(ccc2cccnc12)C(Nc3nccs3)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K22 compound treatment 0.407 0.0801 3.15 0.404 0.0761 1.59 3.3514 0.9501 1118351 IFLab1_001650 Oc1ccc2c(cc(=O)oc2c1O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K23 mock treatment 0.334 0.00706 0.28 0.325 -0.00294 -0.06 0.1529 0.5376 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 K24 positive control 0.086 -0.241 -9.47 0.085 -0.243 -5.08 -10.2933 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L01 compound treatment 0.342 0.0151 0.59 0.348 0.0201 0.42 0.7156 0.9858 1380521 IFLab1_001651 CC(=O)Oc1cc(C)cc2oc(=O)cc(c3ccccc3)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L02 compound treatment 0.355 0.0281 1.1 0.348 0.0201 0.42 1.0771 0.9123 1492849 IFLab1_001652 CCOc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L03 compound treatment 0.334 0.00706 0.28 0.341 0.0131 0.27 0.3896 1.0 1194526 IFLab1_001653 CCCOc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L04 compound treatment 0.33 0.00306 0.12 0.322 -0.00594 -0.12 -0.0027 -0.0157 2066454 IFLab1_001654 O=C(CCC1CCCCC1)NC2=NCCS2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L05 compound treatment 0.331 0.00406 0.16 0.33 0.00206 0.04 0.1435 0.8671 1618364 IFLab1_001655 COc1cc(OC)c2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L06 compound treatment 0.326 -9.37E-4 -0.04 0.321 -0.00694 -0.15 -0.1287 -0.8594 2066455 IFLab1_001656 Cc1nc2ccccc2n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L07 compound treatment 0.333 0.00606 0.24 0.339 0.0111 0.23 0.3322 0.9999 1550371 IFLab1_001657 CCCc1cc(=O)oc2c(CN3CCN(C)CC3)c(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L08 compound treatment 0.337 0.0101 0.4 0.329 0.00106 0.02 0.2955 0.7457 1546436 IFLab1_001658 OCc1nc2ccccc2n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L09 compound treatment 0.349 0.0221 0.87 0.338 0.0101 0.21 0.7623 0.854 1059295 IFLab1_001659 CN1CCN(Cc2c(O)ccc3c4CCCCc4c(=O)oc23)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L10 compound treatment 0.347 0.0201 0.79 0.332 0.00406 0.09 0.6179 0.7788 2066456 IFLab1_001660 O=C1CC(SC(C1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L11 compound treatment 0.334 0.00706 0.28 0.345 0.0171 0.36 0.4488 0.9923 1271679 IFLab1_001661 CCCc1cc(=O)oc2cc(OC(=O)C)cc(OC(=O)C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L12 compound treatment 0.365 0.0381 1.5 0.361 0.0331 0.69 1.5474 0.9386 1531292 IFLab1_001662 O=C(CSc1nnc(NC(=O)C2CC2)s1)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L13 compound treatment 0.349 0.0221 0.87 0.357 0.0291 0.61 1.0434 0.9849 1605587 IFLab1_001663 COc1ccc(cc1)c2cc(=O)c3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L14 compound treatment 0.337 0.0101 0.4 0.348 0.0201 0.42 0.5766 0.9996 2066457 IFLab1_001664 CCCC(=O)Nc1nnc(SCC(=O)Nc2ccccc2C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L15 compound treatment 0.336 0.00906 0.36 0.331 0.00306 0.06 0.2973 0.8211 2066458 IFLab1_001665 COc1ccc(/C=N/c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L16 compound treatment 0.355 0.0281 1.1 0.374 0.0461 0.96 1.4618 0.9977 1570815 IFLab1_001666 O=C(Cc1ccccc1)Nc2nnc(SCC(=O)N3CCCc4ccccc34)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L17 compound treatment 0.367 0.0401 1.58 0.374 0.0461 0.96 1.7954 0.9722 2066459 IFLab1_001667 O=c1[nH]c(cs1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L18 compound treatment 0.36 0.0331 1.3 0.353 0.0251 0.52 1.2901 0.9203 2066460 IFLab1_001668 CC(=O)Nc1nnc(SCc2cccc(c2)C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L19 compound treatment 0.382 0.0551 2.16 0.377 0.0491 1.03 2.2568 0.9419 1424203 IFLab1_001669 COc1ccc(cc1)C(=O)Nc2nc3ccc(F)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L20 compound treatment 0.37 0.0431 1.69 0.367 0.0391 0.82 1.7752 0.9442 1427510 IFLab1_001670 Fc1cccc(CSc2nnc(NC(=O)c3ccccc3)s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L21 compound treatment 0.315 -0.0119 -0.47 0.324 -0.00394 -0.08 -0.3902 -0.8187 2066461 IFLab1_001671 CC1CC(C)CN(C1)C(=O)c2sc3ccccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L22 compound treatment 0.349 0.0221 0.87 0.346 0.0181 0.38 0.8807 0.9307 1180987 IFLab1_001672 CN(C(=O)C(C)(C)C)c1nnc(s1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L23 mock treatment 0.332 0.00506 0.2 0.327 -9.37E-4 -0.02 0.1269 0.6343 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 L24 positive control 0.087 -0.24 -9.43 0.085 -0.243 -5.08 -10.2655 -0.9579 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M01 compound treatment 0.347 0.0201 0.79 0.368 0.0401 0.84 1.1506 0.9995 1654772 IFLab1_001673 Cc1cc(C)c2nc(NC(=O)CCOc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M02 compound treatment 0.333 0.00606 0.24 0.32 -0.00794 -0.17 0.0511 0.1759 2066462 IFLab1_001674 COc1cc(/C=C/2\SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M03 compound treatment 0.309 -0.0179 -0.71 0.303 -0.0249 -0.52 -0.8677 -0.989 1141643 IFLab1_001675 COc1cc(F)ccc1S(=O)(=O)N2CCCCC2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M04 compound treatment 0.381 0.0541 2.13 0.361 0.0331 0.69 1.9923 0.8912 2066463 IFLab1_001676 OC(=O)C(Cc1ccccc1)N2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M05 compound treatment 0.37 0.0431 1.69 0.371 0.0431 0.9 1.8344 0.9564 2066464 IFLab1_001677 CCN1C(=O)/C(=C/c2ccccc2O)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M06 compound treatment 0.33 0.00306 0.12 0.349 0.0211 0.44 0.3968 0.8685 2066465 IFLab1_001678 CCOC(=O)CCN1C(=O)/C(=C/c2ccc(C)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M07 compound treatment 0.347 0.0201 0.79 0.347 0.0191 0.4 0.8398 0.9501 1158506 IFLab1_001679 Cc1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M08 compound treatment 0.335 0.00806 0.32 0.335 0.00706 0.15 0.3287 0.9397 2066466 IFLab1_001680 CC(=O)Nc1c2CSCc2nn1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M09 compound treatment 0.386 0.0591 2.32 0.377 0.0491 1.03 2.368 0.9326 2066467 IFLab1_001681 Cc1ccc(o1)c2nn(cc2/C=N/O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M10 compound treatment 0.386 0.0591 2.32 0.427 0.0991 2.07 3.1079 0.9984 1301858 IFLab1_001682 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M11 compound treatment 0.354 0.0271 1.06 0.335 0.00706 0.15 0.8569 0.7977 2066468 IFLab1_001683 O/N=C/c1cn(nc1c2cccnc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M12 compound treatment 0.342 0.0151 0.59 0.347 0.0191 0.4 0.7008 0.9815 1392605 IFLab1_001684 CCC(CC)C(=O)Nc1c2CSCc2nn1c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M13 compound treatment 0.352 0.0251 0.99 0.336 0.00806 0.17 0.8161 0.8163 2066469 IFLab1_001685 CCOc1ccc(NC(=O)CCCN2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M14 compound treatment 0.339 0.0121 0.47 0.358 0.0301 0.63 0.7802 0.9903 1403471 IFLab1_001686 NC(=O)COc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M15 compound treatment 0.426 0.0991 3.89 0.429 0.101 2.11 4.2496 0.9588 2066470 IFLab1_001687 O=C(CCCN1C(=O)/C(=C/c2ccccc2)/SC1=S)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M16 compound treatment 0.347 0.0201 0.79 0.333 0.00506 0.11 0.6327 0.7949 1545368 IFLab1_001688 CC(Oc1ccc2ccc(=O)oc2c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M17 compound treatment 0.498 0.171 6.73 0.489 0.161 3.37 7.1391 0.949 2066471 IFLab1_001689 OC(=O)c1cccc(c1)N2C(=O)/C(=C/c3ccccc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M18 compound treatment 0.341 0.0141 0.55 0.341 0.0131 0.27 0.5843 0.9472 1517439 IFLab1_001690 COC(=O)c1ccc(COc2cc3oc(=O)cc(C)c3cc2Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M19 compound treatment 0.658 0.331 13.02 0.646 0.318 6.66 13.9106 0.9515 2066472 IFLab1_001691 CSCCC(N1C(=O)/C(=C/c2ccc(C)cc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M20 compound treatment 0.332 0.00506 0.2 0.326 -0.00194 -0.04 0.1121 0.5517 1576198 IFLab1_001692 CCCc1c(C)c2c(OCC)cc(OCC)cc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M21 compound treatment 0.4 0.0731 2.87 0.419 0.0911 1.91 3.3787 0.9801 2066473 IFLab1_001693 Fc1ccc(cc1)C(CC(=O)c2ccco2)SCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M22 compound treatment 0.403 0.0761 2.99 0.441 0.113 2.37 3.7877 0.9933 1673658 IFLab1_001694 Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M23 mock treatment 0.31 -0.0169 -0.67 0.332 0.00406 0.09 -0.4108 -0.6119 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 M24 positive control 0.09 -0.237 -9.32 0.087 -0.241 -5.04 -10.1525 -0.9584 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N01 compound treatment 0.335 0.00806 0.32 0.336 0.00806 0.17 0.3435 0.9564 1303158 IFLab1_001695 COc1cc(C)cc2oc(=O)cc(c3ccccc3)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N02 compound treatment 0.329 0.00206 0.08 0.331 0.00306 0.06 0.1027 0.9932 1311259 IFLab1_001696 CCOc1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N03 compound treatment 0.331 0.00406 0.16 0.326 -0.00194 -0.04 0.0843 0.5114 1359118 IFLab1_001697 COC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N04 compound treatment 0.329 0.00206 0.08 0.322 -0.00594 -0.12 -0.0305 -0.2057 1267907 IFLab1_001698 COC(=O)c1ccccc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N05 compound treatment 0.336 0.00906 0.36 0.325 -0.00294 -0.06 0.2085 0.5766 1594889 IFLab1_001699 CCOc1cc(OCC)c2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N06 compound treatment 0.345 0.0181 0.71 0.343 0.0151 0.32 0.7251 0.9332 1617261 IFLab1_001700 OCCCc1nc2ccccc2n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N07 compound treatment 0.339 0.0121 0.47 0.341 0.0131 0.27 0.5286 0.9657 1481154 IFLab1_001701 CCCc1cc(=O)oc2c(CN3CCOCC3)c(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N08 compound treatment 0.331 0.00406 0.16 0.329 0.00106 0.02 0.1287 0.7978 2066474 IFLab1_001702 CCCn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N09 compound treatment 0.354 0.0271 1.06 0.352 0.0241 0.5 1.1084 0.9416 1059294 IFLab1_001703 Oc1ccc2c3CCCCc3c(=O)oc2c1CN4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N10 compound treatment 0.357 0.0301 1.18 0.342 0.0141 0.29 1.0439 0.857 1313591 IFLab1_001704 Cc1ccc(cc1)C2CC(=O)CC(S2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N11 compound treatment 0.352 0.0251 0.99 0.355 0.0271 0.57 1.0972 0.9654 1335067 IFLab1_001705 CCCc1cc(=O)oc2cc(O)cc(O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N12 compound treatment 0.378 0.0511 2.01 0.366 0.0381 0.8 1.9829 0.918 1360502 IFLab1_001706 O=C(CSc1nnc(NC(=O)c2ccccc2)s1)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N13 compound treatment 0.353 0.0261 1.02 0.352 0.0241 0.5 1.0806 0.9465 2066475 IFLab1_001707 Clc1ccc2c(=O)cc(oc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N14 compound treatment 0.343 0.0161 0.63 0.34 0.0121 0.25 0.6251 0.919 1544143 IFLab1_001708 Fc1ccc(NC(=O)CSc2nnc(NC(=O)C3CCCCC3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N15 compound treatment 0.348 0.0211 0.83 0.35 0.0221 0.46 0.912 0.9619 2066476 IFLab1_001709 Fc1ccc(/C=C/C(=O)\C=C\c2ccc(F)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N16 compound treatment 0.353 0.0261 1.02 0.348 0.0201 0.42 1.0215 0.9224 1568818 IFLab1_001710 Cc1ccc(cc1)C(=O)Nc2nnc(SCC(=O)N3CCCc4ccccc34)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N17 compound treatment 0.385 0.0581 2.28 0.369 0.0411 0.86 2.2219 0.9109 1624156 IFLab1_001711 Nc1ccc(cc1)c2cc(C(=O)O)c3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N18 compound treatment 0.355 0.0281 1.1 0.351 0.0231 0.48 1.1215 0.9312 1732206 IFLab1_001712 CCC(=O)Nc1nnc(SCc2ccc(Br)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N19 compound treatment 0.362 0.0351 1.38 0.388 0.0601 1.26 1.8636 0.9989 1231750 IFLab1_001713 COc1cccc(c1)C(=O)Nc2nc3ccc(F)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N20 compound treatment 0.366 0.0391 1.54 0.357 0.0291 0.61 1.5161 0.9178 1231846 IFLab1_001714 COc1ccccc1C(=O)Nc2nnc(SCc3cccc(F)c3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N21 compound treatment 0.379 0.0521 2.05 0.379 0.0511 1.07 2.203 0.9541 2066477 IFLab1_001715 CCOC(=O)c1sc(cc1N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N22 compound treatment 0.397 0.0701 2.75 0.412 0.0841 1.76 3.1918 0.9765 2066478 IFLab1_001716 COC(=O)c1ccccc1N/C=C\2/SC(=S)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N23 mock treatment 0.335 0.00806 0.32 0.33 0.00206 0.04 0.2547 0.796 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 N24 positive control 0.09 -0.237 -9.32 0.088 -0.24 -5.02 -10.1377 -0.9579 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O01 compound treatment 0.333 0.00606 0.24 0.344 0.0161 0.34 0.4062 0.9858 1672421 IFLab1_001717 Oc1ccc(NC(=O)CCOc2ccccc2)cc1c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O02 compound treatment 0.333 0.00606 0.24 0.328 6.25E-5 0.0 0.1695 0.711 2066479 IFLab1_001718 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C/c3cccs3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O03 compound treatment 0.325 -0.00194 -0.08 0.324 -0.00394 -0.08 -0.1121 -0.9992 1634906 IFLab1_001719 COc1ccc(Cl)cc1S(=O)(=O)N2CCCCC2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O04 compound treatment 0.33 0.00306 0.12 0.318 -0.00994 -0.21 -0.0619 -0.2576 2066480 IFLab1_001720 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccc(C)cc3)/c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O05 compound treatment 0.212 -0.115 -4.52 0.211 -0.117 -2.45 -4.9258 -0.9585 2066481 IFLab1_001721 CCN1C(=O)/C(=C\c2ccc(C)o2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O06 compound treatment 0.338 0.0111 0.43 0.338 0.0101 0.21 0.4565 0.9446 2066482 IFLab1_001722 CCOC(=O)CCN1C(=O)/C(=C/c2ccccc2OC)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O07 compound treatment 0.348 0.0211 0.83 0.363 0.0351 0.73 1.1044 0.9982 2066483 IFLab1_001723 CCc1ccc(cc1)c2cn3ccsc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O08 compound treatment 0.344 0.0171 0.67 0.346 0.0181 0.38 0.7416 0.9632 2066484 IFLab1_001724 CC(=O)Nc1c2CSCc2nn1C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O09 compound treatment 0.355 0.0281 1.1 0.35 0.0221 0.46 1.1067 0.9253 2066485 IFLab1_001725 O/N=C/c1cn(nc1c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O10 compound treatment 0.415 0.0881 3.46 0.388 0.0601 1.26 3.3371 0.9059 1543452 IFLab1_001726 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O11 compound treatment 0.344 0.0171 0.67 0.337 0.00906 0.19 0.6085 0.8728 2066486 IFLab1_001727 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O12 compound treatment 0.423 0.0961 3.78 0.389 0.0611 1.28 3.5743 0.8964 1172810 IFLab1_001728 Cc1cccc(c1)n2nc3CSCc3c2NC(=O)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O13 compound treatment 0.352 0.0251 0.99 0.348 0.0201 0.42 0.9937 0.9277 2066487 IFLab1_001729 Cc1ccc(/C=C\2/SC(=O)N(CCC(=O)O)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O14 compound treatment 0.349 0.0221 0.87 0.35 0.0221 0.46 0.9398 0.9564 1256406 IFLab1_001730 Fc1ccccc1COc2ccc3ccc(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O15 compound treatment 0.444 0.117 4.6 0.437 0.109 2.28 4.8684 0.9476 1064179 IFLab1_001731 FC(F)(F)c1cccc(c1)N2C(=O)CSC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O16 compound treatment 0.348 0.0211 0.83 0.35 0.0221 0.46 0.912 0.9619 1377440 IFLab1_001732 Cc1cc(=O)oc2cc(OCc3ccccc3F)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O17 compound treatment 0.374 0.0471 1.85 0.367 0.0391 0.82 1.8864 0.9325 2066488 IFLab1_001733 CCCOC(=O)C(C)N1C(=O)/C(=C/c2ccc(OC)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O18 compound treatment 0.345 0.0181 0.71 0.337 0.00906 0.19 0.6363 0.8656 1140550 IFLab1_001734 CCCc1cc(=O)oc2cc(OC(=O)C)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O19 compound treatment 0.779 0.452 17.77 0.741 0.413 8.64 18.6804 0.9451 2066489 IFLab1_001735 CSCCC(N1C(=O)/C(=C/c2ccc(O)cc2)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O20 compound treatment 0.349 0.0221 0.87 0.364 0.0361 0.75 1.147 0.9976 1240833 IFLab1_001736 Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O21 compound treatment 0.346 0.0191 0.75 0.328 6.25E-5 0.0 0.5309 0.7083 2066490 IFLab1_001737 Nc1nc(cs1)c2cc(Cl)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O22 compound treatment 0.347 0.0201 0.79 0.345 0.0171 0.36 0.8103 0.9358 1616603 IFLab1_001738 CC(=O)Oc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O23 mock treatment 0.334 0.00706 0.28 0.334 0.00606 0.13 0.2861 0.937 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 O24 positive control 0.093 -0.234 -9.2 0.09 -0.238 -4.98 -10.0247 -0.9585 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P01 compound treatment 0.34 0.0131 0.51 0.34 0.0121 0.25 0.5417 0.9465 1366445 IFLab1_001739 COC(=O)C(C)Oc1cc(C)cc2oc(=O)cc(c3ccccc3)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P02 compound treatment 0.347 0.0201 0.79 0.335 0.00706 0.15 0.6623 0.8252 1677477 IFLab1_001740 CCOc1ccccc1NC(=O)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P03 compound treatment 0.347 0.0201 0.79 0.348 0.0201 0.42 0.8546 0.9564 1298345 IFLab1_001741 CCOC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P04 compound treatment 0.367 0.0401 1.58 0.372 0.0441 0.92 1.7658 0.9675 1358453 IFLab1_001742 COC(=O)c1ccc(C)c(NC(=O)C(C)NC(=O)C(c2ccccc2)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P05 compound treatment 0.371 0.0441 1.73 0.373 0.0451 0.94 1.8918 0.9591 1377920 IFLab1_001743 Cc1c(OCC(=O)N)ccc2c3CCCCc3c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P06 compound treatment 0.383 0.0561 2.2 0.369 0.0411 0.86 2.1663 0.9156 1170966 IFLab1_001744 CC(O)c1nc2ccccc2n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P07 compound treatment 0.382 0.0551 2.16 0.389 0.0611 1.28 2.4344 0.9684 1377722 IFLab1_001745 CCCc1cc(=O)oc2c(CN3CCCC3)c(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P08 compound treatment 0.353 0.0261 1.02 0.367 0.0391 0.82 1.3026 0.9937 1735834 IFLab1_001746 CC(C)Cn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P09 compound treatment 0.391 0.0641 2.52 0.419 0.0911 1.91 3.1285 0.9905 1545681 IFLab1_001747 Oc1ccc2c3CCCc3c(=O)oc2c1CN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P10 compound treatment 0.376 0.0491 1.93 0.392 0.0641 1.34 2.312 0.9842 1175371 IFLab1_001748 CC1(O)CC(SC(C1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P11 compound treatment 0.377 0.0501 1.97 0.366 0.0381 0.8 1.9551 0.9207 1588913 IFLab1_001749 CC(=CCOc1ccc2c(c1)oc(=O)c3ccccc32)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P12 compound treatment 0.393 0.0661 2.6 0.381 0.0531 1.11 2.6218 0.9281 1684952 IFLab1_001750 CC(C)CC(=O)Nc1nnc(SCC(=O)Nc2ccc(C)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P13 compound treatment 0.365 0.0381 1.5 0.385 0.0571 1.19 1.9026 0.9937 1087106 IFLab1_001751 CC(=O)Nc1ccc2C(=O)CCc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P14 compound treatment 0.388 0.0611 2.4 0.373 0.0451 0.94 2.3645 0.9167 1195268 IFLab1_001752 Cc1ccccc1C(=O)Nc2nnc(SCC(=O)Nc3ccc(F)cc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P15 compound treatment 0.394 0.0671 2.64 0.399 0.0711 1.49 2.916 0.9633 2066491 IFLab1_001753 O=C/1/C(=C/c2ccco2)/CC\C1=C/c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P16 compound treatment 0.361 0.0341 1.34 0.355 0.0271 0.57 1.3475 0.9267 1573578 IFLab1_001754 CC(=O)Nc1nnc(SCC(=O)N2CCc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P17 compound treatment 0.364 0.0371 1.46 0.353 0.0251 0.52 1.4013 0.9048 1437274 IFLab1_001755 CC(=O)NC1(CC2CC3CC(CC(=O)O)(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P18 compound treatment 0.355 0.0281 1.1 0.361 0.0331 0.69 1.2694 0.9747 1361597 IFLab1_001756 CC(=O)Nc1nnc(SCc2cccc(F)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P19 compound treatment 0.358 0.0311 1.22 0.349 0.0211 0.44 1.1753 0.9052 1473279 IFLab1_001757 CN(C)c1ccc(cc1)C(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P20 compound treatment 0.36 0.0331 1.3 0.346 0.0181 0.38 1.1865 0.8764 1116608 IFLab1_001758 CCOC(=O)CSc1nnc(NC(=O)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P21 compound treatment 0.363 0.0361 1.42 0.351 0.0231 0.48 1.3439 0.8972 1558744 IFLab1_001759 O=C(Nc1nc2ccccc2s1)c3cc(=O)c4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P22 compound treatment 0.363 0.0361 1.42 0.357 0.0291 0.61 1.4327 0.9286 2066492 IFLab1_001760 CCc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P23 mock treatment 0.348 0.0211 0.83 0.346 0.0181 0.38 0.8529 0.9369 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1416 P24 positive control 0.096 -0.231 -9.08 0.093 -0.235 -4.92 -9.8969 -0.9585 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A01 compound treatment 0.34 0.0113 0.44 0.345 0.0164 0.34 0.5577 0.9919 1706923 IFLab1_001761 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3cccs3)SCC(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A02 compound treatment 0.313 -0.0157 -0.62 0.316 -0.0126 -0.26 -0.622 -0.9277 2066493 IFLab1_001762 Fc1ccc(cc1Cl)N2C(SCC2=O)c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A03 compound treatment 0.319 -0.00969 -0.38 0.325 -0.00356 -0.07 -0.322 -0.8298 2066494 IFLab1_001763 COC(=O)[C@H]1C(C(=C(NC1=O)SC)C#N)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A04 compound treatment 0.318 -0.0107 -0.42 0.326 -0.00256 -0.05 -0.3351 -0.7909 2066495 IFLab1_001764 Cc1nnc(NC(=O)c2ccccc2C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A05 compound treatment 0.321 -0.00769 -0.3 0.352 0.0234 0.49 0.1331 0.231 1619755 IFLab1_001765 NC(=O)CSC1=C(C#N)C(C(C#N)C(=O)N1)c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A06 compound treatment 0.315 -0.0137 -0.54 0.327 -0.00156 -0.03 -0.4037 -0.7487 2066496 IFLab1_001766 CC(C)c1nnc(NC(=O)c2ccccc2C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A07 compound treatment 0.358 0.0293 1.15 0.34 0.0114 0.24 0.9842 0.8361 2066497 IFLab1_001767 *c1ccccc1C2C(=O)N(C)c3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A08 compound treatment 0.324 -0.00469 -0.18 0.325 -0.00356 -0.07 -0.183 -0.9207 1500808 IFLab1_001768 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(Cl)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A09 compound treatment 0.324 -0.00469 -0.18 0.319 -0.00956 -0.2 -0.2718 -0.9992 1510133 IFLab1_001769 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A10 compound treatment 0.325 -0.00369 -0.14 0.355 0.0264 0.55 0.2887 0.5048 1622222 IFLab1_001770 Cc1ccc2n(C)c(=NC(=O)c3cccc(c3)N4C(=O)CCC4=O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A11 compound treatment 0.356 0.0273 1.07 0.321 -0.00756 -0.16 0.6474 0.5965 1038790 IFLab1_001771 COc1ccc(C#CC(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A12 compound treatment 0.325 -0.00369 -0.14 0.339 0.0104 0.22 0.0519 0.1981 2066498 IFLab1_001772 BrC(=C)CSCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A13 compound treatment 0.325 -0.00369 -0.14 0.331 0.00244 0.05 -0.0665 -0.4324 2066499 IFLab1_001773 COc1ccc2nc(NC(=O)/C=C/c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A14 compound treatment 0.327 -0.00169 -0.07 0.34 0.0114 0.24 0.1223 0.4925 1322719 IFLab1_001774 CCC(C)Sc1nnc(NC(=O)c2cc(Cl)ccc2OC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A15 compound treatment 0.36 0.0313 1.23 0.32 -0.00856 -0.18 0.7438 0.5979 1710534 IFLab1_001775 CC1CC(C)CN(C1)C(=O)c2ccc(cc2)S(=O)(=O)N3CC(C)CC(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A16 compound treatment 0.328 -6.88E-4 -0.03 0.335 0.00644 0.13 0.0761 0.5542 1918857 IFLab1_001776 S=c1sc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A17 compound treatment 0.326 -0.00269 -0.11 0.329 4.38E-4 0.01 -0.0682 -0.6434 1197782 IFLab1_001777 O=C(CN1C(=O)CCC1=O)Nc2ccc3CCc4cccc2c43 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A18 compound treatment 0.326 -0.00269 -0.11 0.327 -0.00156 -0.03 -0.0978 -0.8845 1250804 IFLab1_001778 OC(c1ccccc1)c2nccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A19 compound treatment 0.335 0.00631 0.25 0.352 0.0234 0.49 0.5223 0.9502 1304828 IFLab1_001779 COc1cccc(c1)C(=O)N=c2sc3cc(Cl)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A20 compound treatment 0.43 0.101 3.98 0.414 0.0854 1.79 4.0809 0.9347 2066500 IFLab1_001780 CN1/C(=C\C=N\c2ccc(cc2)C(=O)O)/C(C)(C)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A21 compound treatment 0.321 -0.00769 -0.3 0.322 -0.00656 -0.14 -0.3108 -0.9363 1002763 IFLab1_001781 OC(=O)c1cccc(n1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A22 compound treatment 0.344 0.0153 0.6 0.327 -0.00156 -0.03 0.4026 0.6677 1380195 IFLab1_001782 O=C(N1CCOCC1)c2ccc(cc2)S(=O)(=O)N3CCc4ccccc4C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A23 mock treatment 0.323 -0.00569 -0.22 0.343 0.0144 0.3 0.0555 0.1477 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 A24 positive control 0.078 -0.251 -9.86 0.078 -0.251 -5.24 -10.6772 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B01 compound treatment 0.337 0.00831 0.33 0.345 0.0164 0.34 0.4743 0.9997 2066501 IFLab1_001783 Fc1ccc(cc1)C(=O)COC(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B02 compound treatment 0.336 0.00731 0.29 0.329 4.38E-4 0.01 0.2098 0.7293 1519483 IFLab1_001784 CCOc1ccccc1Nc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B03 compound treatment 0.346 0.0173 0.68 0.335 0.00644 0.13 0.5766 0.8309 2066502 IFLab1_001785 CCn1c(C)cc(C)[n+]1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B04 compound treatment 0.342 0.0133 0.52 0.344 0.0154 0.32 0.5985 0.9731 1430925 IFLab1_001786 CN(Cc1ccccc1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B05 compound treatment 0.342 0.0133 0.52 0.348 0.0194 0.41 0.6577 0.9922 2066503 IFLab1_001787 Cc1ccc(Nc2ccc(C)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B06 compound treatment 0.328 -6.88E-4 -0.03 0.319 -0.00956 -0.2 -0.1606 -0.7954 1234994 IFLab1_001788 C(CC1=CCCCC1)Nc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B07 compound treatment 0.331 0.00231 0.09 0.338 0.00944 0.2 0.2039 0.938 2066504 IFLab1_001789 O/C(=N\c1ccccc1)/NC2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B08 compound treatment 0.335 0.00631 0.25 0.344 0.0154 0.32 0.4039 0.9915 1158576 IFLab1_001790 Cc1ccc(c(C)c1)n2ncc3c(NCCO)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B09 compound treatment 0.349 0.0203 0.8 0.358 0.0294 0.62 1.0003 0.9918 2066505 IFLab1_001791 Cc1sc[n+](CC(=O)c2ccc(Br)cc2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B10 compound treatment 0.342 0.0133 0.52 0.345 0.0164 0.34 0.6133 0.9793 1237630 IFLab1_001792 CN1CCc2c(C(=O)N)c(NC(=O)c3ccco3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B11 compound treatment 0.342 0.0133 0.52 0.339 0.0104 0.22 0.5246 0.9249 1587647 IFLab1_001793 OCc1cc(=O)c(O)c(CN2CCCCC2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B12 compound treatment 0.334 0.00531 0.21 0.345 0.0164 0.34 0.3909 0.9714 1312557 IFLab1_001794 COc1ccc(cc1)C(=O)NCc2nnc(SC)n2C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B13 compound treatment 0.33 0.00131 0.05 0.328 -5.62E-4 -0.01 0.0282 0.5321 1319457 IFLab1_001795 CSc1nnc(CNC(=O)COc2ccccc2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B14 compound treatment 0.342 0.0133 0.52 0.347 0.0184 0.39 0.6429 0.9887 2066506 IFLab1_001796 O=C(Nc1nnc(s1)c2ccccc2)/C=C\c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B15 compound treatment 0.339 0.0103 0.41 0.342 0.0134 0.28 0.4855 0.984 1661799 IFLab1_001797 CSc1nnc(NC(=O)C2CCCCC2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B16 compound treatment 0.341 0.0123 0.48 0.324 -0.00456 -0.1 0.2748 0.5569 1717952 IFLab1_001798 CCOC(=O)C(CC)Sc1nnc(NC(=O)Cc2cccs2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B17 compound treatment 0.35 0.0213 0.84 0.356 0.0274 0.57 0.9985 0.983 1118747 IFLab1_001799 COc1cccc(c1)C(=O)Nc2nnc(SCc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B18 compound treatment 0.328 -6.88E-4 -0.03 0.328 -5.62E-4 -0.01 -0.0274 -0.9306 1238367 IFLab1_001800 COC(CNc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B19 compound treatment 0.336 0.00731 0.29 0.345 0.0164 0.34 0.4465 0.996 1444994 IFLab1_001801 CSc1nnc(NC(=O)C2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B20 compound treatment 0.34 0.0113 0.44 0.342 0.0134 0.28 0.5133 0.9755 1173596 IFLab1_001802 CCC(=O)N1CCc2cc(OC)c(OC)cc2C1COc3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B21 compound treatment 0.327 -0.00169 -0.07 0.349 0.0204 0.43 0.2555 0.5903 1713021 IFLab1_001803 Cc1ccc(c(C)c1)n2ncc3c(NCc4ccco4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B22 compound treatment 0.336 0.00731 0.29 0.335 0.00644 0.13 0.2986 0.9403 1385028 IFLab1_001804 O=C(CCc1ccccc1)N2CCN(CC2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B23 mock treatment 0.329 3.12E-4 0.01 0.331 0.00244 0.05 0.0448 0.853 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 B24 positive control 0.078 -0.251 -9.86 0.078 -0.251 -5.24 -10.6772 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C01 compound treatment 0.341 0.0123 0.48 0.337 0.00844 0.18 0.4672 0.9066 1252379 IFLab1_001805 C=CCSC1=C(C#N)C(CC(=O)N1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C02 compound treatment 0.326 -0.00269 -0.11 0.327 -0.00156 -0.03 -0.0978 -0.8845 1695744 IFLab1_001806 O=C(Nc1nnc(s1)c2ccccc2)c3ccc4ccccc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C03 compound treatment 0.325 -0.00369 -0.14 0.332 0.00344 0.07 -0.0517 -0.3192 2066507 IFLab1_001807 CCOc1ccccc1C2[C@H](C(=O)OC)C(=O)NC(=C2C#N)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C04 compound treatment 0.336 0.00731 0.29 0.344 0.0154 0.32 0.4317 0.9983 1211582 IFLab1_001808 Cc1nnc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C05 compound treatment 0.333 0.00431 0.17 0.339 0.0104 0.22 0.2743 0.9922 1437597 IFLab1_001809 Clc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C06 compound treatment 0.339 0.0103 0.41 0.34 0.0114 0.24 0.456 0.9684 1546770 IFLab1_001810 CC(C)c1nnc(NC(=O)c2cc(Br)ccc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C07 compound treatment 0.338 0.00931 0.37 0.333 0.00444 0.09 0.3246 0.8592 1714685 IFLab1_001811 Brc1ccc2[nH]c(=O)c(NC(=O)c3ccccc3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C08 compound treatment 0.34 0.0113 0.44 0.343 0.0144 0.3 0.5281 0.9822 1362589 IFLab1_001812 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C09 compound treatment 0.338 0.00931 0.37 0.341 0.0124 0.26 0.4429 0.986 1217478 IFLab1_001813 Cc1cc(C)c(c(C)c1)S(=O)(=O)NC(CC(=O)O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C10 compound treatment 0.339 0.0103 0.41 0.338 0.00944 0.2 0.4264 0.9453 2066508 IFLab1_001814 CCCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C11 compound treatment 0.371 0.0423 1.66 0.377 0.0484 1.01 1.8931 0.9718 1347042 IFLab1_001815 O=C(CCSc1ccccc1)Nc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C12 compound treatment 0.343 0.0143 0.56 0.348 0.0194 0.41 0.6855 0.9873 1364584 IFLab1_001816 CCOC(=O)C(C)Sc1nnc(NC(=O)c2c(F)cccc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C13 compound treatment 0.321 -0.00769 -0.3 0.32 -0.00856 -0.18 -0.3404 -0.9688 2066509 IFLab1_001817 Brc1ccc2nc(NC(=O)/C=C/c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C14 compound treatment 0.327 -0.00169 -0.07 0.326 -0.00256 -0.05 -0.0848 -0.9944 2066510 IFLab1_001818 CCC(C)Sc1nnc(NC(=O)c2ccccc2C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C15 compound treatment 0.334 0.00531 0.21 0.336 0.00744 0.16 0.2578 0.9895 1565540 IFLab1_001819 Brc1ccc2nc(NC(=O)CN3C(=O)CCC3=O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C16 compound treatment 0.425 0.0963 3.79 0.448 0.119 2.5 4.445 0.9797 1343195 IFLab1_001820 CCN1C(=O)c2cccc3c(N)ccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C17 compound treatment 0.339 0.0103 0.41 0.331 0.00244 0.05 0.3228 0.7898 1235040 IFLab1_001821 O=C(CN1C(=O)CCC1=O)Nc2ccccc2Oc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C18 compound treatment 0.346 0.0173 0.68 0.348 0.0194 0.41 0.7689 0.9697 1307874 IFLab1_001822 O=C(OC(c1ccccc1)c2nccc3ccccc23)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C19 compound treatment 0.323 -0.00569 -0.22 0.333 0.00444 0.09 -0.0925 -0.3819 1734067 IFLab1_001823 COc1ccccc1C(=O)N=c2sc3cc(Cl)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C20 compound treatment 0.333 0.00431 0.17 0.323 -0.00556 -0.12 0.0376 0.1828 2066511 IFLab1_001824 C(OCc1nc2ccccc2s1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C21 compound treatment 0.335 0.00631 0.25 0.338 0.00944 0.2 0.3151 0.9936 1026938 IFLab1_001825 CC(=O)n1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C22 compound treatment 0.326 -0.00269 -0.11 0.325 -0.00356 -0.07 -0.1274 -0.9854 1138266 IFLab1_001826 COc1ccc(C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C23 mock treatment 0.324 -0.00469 -0.18 0.325 -0.00356 -0.07 -0.183 -0.9207 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 C24 positive control 0.08 -0.249 -9.78 0.079 -0.25 -5.22 -10.6068 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D01 compound treatment 0.34 0.0113 0.44 0.356 0.0274 0.57 0.7205 0.992 1265183 IFLab1_001827 COC(=O)C1=C(C)NC(=C(C1c2cccs2)C(=O)OC)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D02 compound treatment 0.331 0.00231 0.09 0.334 0.00544 0.11 0.1448 0.9938 1726080 IFLab1_001828 CSc1ccccc1Nc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D03 compound treatment 0.341 0.0123 0.48 0.353 0.0244 0.51 0.7039 0.9996 1495117 IFLab1_001829 COC(=O)c1ccc(NC2SC(=O)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D04 compound treatment 0.322 -0.00669 -0.26 0.337 0.00844 0.18 -0.0611 -0.1928 1308000 IFLab1_001830 CC1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D05 compound treatment 0.318 -0.0107 -0.42 0.335 0.00644 0.13 -0.2019 -0.4575 1239434 IFLab1_001831 Clc1ccc(cc1)C2=CSc3nnc(Cc4ccccc4)n3N2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D06 compound treatment 0.321 -0.00769 -0.3 0.339 0.0104 0.22 -0.0593 -0.159 1206698 IFLab1_001832 OCCNc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D07 compound treatment 0.328 -6.88E-4 -0.03 0.341 0.0124 0.26 0.1649 0.6303 2066512 IFLab1_001833 CCCc1n(C)c2ccccc2[n+]1CC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D08 compound treatment 0.327 -0.00169 -0.07 0.301 -0.0276 -0.58 -0.4548 -0.7833 1173648 IFLab1_001834 CCOC(=O)c1c(NC(=O)C)sc2CN(CCc12)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D09 compound treatment 0.347 0.0183 0.72 0.347 0.0184 0.39 0.7819 0.9572 2066513 IFLab1_001835 O/N=C/c1ccc(o1)c2cc(Cl)ccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D10 compound treatment 0.334 0.00531 0.21 0.336 0.00744 0.16 0.2578 0.9895 1536384 IFLab1_001836 NC(=O)c1c(NC(=O)COc2ccc(Cl)cc2)sc3CN(Cc4ccccc4)CCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D11 compound treatment 0.344 0.0153 0.6 0.342 0.0134 0.28 0.6246 0.9399 1369784 IFLab1_001837 OCc1cc(=O)c(O)c(CN2CCc3ccccc3C2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D12 compound treatment 0.344 0.0153 0.6 0.337 0.00844 0.18 0.5506 0.8775 2066514 IFLab1_001838 CCn1c(CNC(=O)c2ccc(OC)cc2)nnc1SC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D13 compound treatment 0.339 0.0103 0.41 0.336 0.00744 0.16 0.3968 0.9135 2066515 IFLab1_001839 CSc1nnc(CNC(=O)c2cccs2)n1c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D14 compound treatment 0.33 0.00131 0.05 0.317 -0.0116 -0.24 -0.1346 -0.5441 2066516 IFLab1_001840 COc1ccc(/C=C/C(=O)Nc2nnc(s2)c3ccccc3)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D15 compound treatment 0.347 0.0183 0.72 0.343 0.0144 0.3 0.7228 0.9256 1474513 IFLab1_001841 O=C(Nc1nnc(SCc2ccccc2)s1)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D16 compound treatment 0.347 0.0183 0.72 0.353 0.0244 0.51 0.8707 0.9859 1123435 IFLab1_001842 O=C(Cc1cccs1)Nc2nnc(SCC(=O)N3CCCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D17 compound treatment 0.352 0.0233 0.92 0.352 0.0234 0.49 0.9949 0.9571 2066517 IFLab1_001843 CSc1nnc(NC(=O)c2ccc(C)c(C)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D18 compound treatment 0.32 -0.00869 -0.34 0.318 -0.0106 -0.22 -0.3978 -0.9778 1262419 IFLab1_001844 OCCNc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D19 compound treatment 0.343 0.0143 0.56 0.346 0.0174 0.36 0.6559 0.978 1599675 IFLab1_001845 CCCSc1nnc(NC(=O)C2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D20 compound treatment 0.344 0.0153 0.6 0.347 0.0184 0.39 0.6985 0.9769 1466906 IFLab1_001846 COc1ccccc1OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D21 compound treatment 0.335 0.00631 0.25 0.338 0.00944 0.2 0.3151 0.9936 1290646 IFLab1_001847 C(Nc1ncnc2n(ncc12)c3ccccc3)C4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D22 compound treatment 0.361 0.0323 1.27 0.373 0.0444 0.93 1.5559 0.9882 1241725 IFLab1_001848 COc1cccc2sc(NC(=O)C3COc4ccccc4O3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D23 mock treatment 0.327 -0.00169 -0.07 0.322 -0.00656 -0.14 -0.144 -0.9443 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 D24 positive control 0.081 -0.248 -9.74 0.081 -0.248 -5.18 -10.5494 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E01 compound treatment 0.328 -6.88E-4 -0.03 0.349 0.0204 0.43 0.2833 0.6611 2066518 IFLab1_001849 Cc1[nH]nc2OC(=C(C#N)C(CCc3ccccc3)c12)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E02 compound treatment 0.356 0.0273 1.07 0.356 0.0274 0.57 1.1653 0.957 2066519 IFLab1_001850 FC(F)(F)c1ccccc1C(=O)Nc2nnc(s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E03 compound treatment 0.336 0.00731 0.29 0.336 0.00744 0.16 0.3134 0.9585 1227743 IFLab1_001851 CCCSC1=C(C#N)C(CC(=O)N1)c2cc(Br)c(O)c(OC)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E04 compound treatment 0.337 0.00831 0.33 0.328 -5.62E-4 -0.01 0.2228 0.6812 1170244 IFLab1_001852 CCc1nnc(NC(=O)c2c(OC)cccc2OC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E05 compound treatment 0.326 -0.00269 -0.11 0.334 0.00544 0.11 0.0057 0.037 1694562 IFLab1_001853 COC(=O)CSC1=C(C#N)C(C(C#N)C(=O)N1)c2ccccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E06 compound treatment 0.343 0.0143 0.56 0.341 0.0124 0.26 0.582 0.9386 1430816 IFLab1_001854 CC(C)c1nnc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E07 compound treatment 0.34 0.0113 0.44 0.329 4.38E-4 0.01 0.321 0.7215 1694711 IFLab1_001855 CC(=O)Nc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E08 compound treatment 0.347 0.0183 0.72 0.335 0.00644 0.13 0.6044 0.8251 1456677 IFLab1_001856 O=C(NC1SC2=C(CCCC2)C1C#N)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E09 compound treatment 0.356 0.0273 1.07 0.358 0.0294 0.62 1.1949 0.9652 1211135 IFLab1_001857 Oc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1C3CCCC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E10 compound treatment 0.345 0.0163 0.64 0.35 0.0214 0.45 0.7707 0.9847 2066520 IFLab1_001858 CCCc1nc2ccccc2n1CCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E11 compound treatment 0.352 0.0233 0.92 0.349 0.0204 0.43 0.9506 0.9398 2066521 IFLab1_001859 O=C(CCSc1ccccc1)Nc2nc(cs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E12 compound treatment 0.38 0.0513 2.02 0.385 0.0564 1.18 2.2617 0.9675 1249277 IFLab1_001860 CCOC(=O)C(C)Sc1nnc(NC(=O)c2ccc3ccccc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E13 compound treatment 0.38 0.0513 2.02 0.382 0.0534 1.12 2.2173 0.9613 2066522 IFLab1_001861 O=C(Nc1nc2CCCCc2s1)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E14 compound treatment 0.394 0.0653 2.57 0.393 0.0644 1.35 2.7693 0.9548 1556070 IFLab1_001862 CC(C)Sc1nnc(NC(=O)c2ccc3ccccc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E15 compound treatment 0.343 0.0143 0.56 0.349 0.0204 0.43 0.7003 0.9908 1131316 IFLab1_001863 CC1CCc2nc(NC(=O)CN3C(=O)CCC3=O)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E16 compound treatment 0.415 0.0863 3.39 0.417 0.0884 1.85 3.7083 0.9593 1161051 IFLab1_001864 Cc1ccc(cc1)C(CC(=O)c2ccco2)Sc3ccccc3N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E17 compound treatment 0.338 0.00931 0.37 0.349 0.0204 0.43 0.5613 0.997 1197512 IFLab1_001865 O=C(CN1C(=O)CCC1=O)Nc2sc3CCCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E18 compound treatment 0.341 0.0123 0.48 0.353 0.0244 0.51 0.7039 0.9996 1253412 IFLab1_001866 Oc1c(CN2CCCCC2)cc(Cl)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E19 compound treatment 0.333 0.00431 0.17 0.334 0.00544 0.11 0.2004 0.9812 1212707 IFLab1_001867 CCOc1ccc(cc1)C(=O)N=c2sc3cc(Cl)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E20 compound treatment 0.334 0.00531 0.21 0.339 0.0104 0.22 0.3021 0.9998 1670069 IFLab1_001868 CC1COc2c(F)c(F)cc3c(=O)c(cn1c23)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E21 compound treatment 0.383 0.0543 2.14 0.393 0.0644 1.35 2.4635 0.9754 1157091 IFLab1_001869 CC(=O)N(C1SC(=O)N(C1=O)c2ccc(C)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E22 compound treatment 0.337 0.00831 0.33 0.343 0.0144 0.3 0.4447 0.9992 1241476 IFLab1_001870 COC(=O)c1ccc(cc1)C(=O)Nc2nc3ccc(C)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E23 mock treatment 0.329 3.12E-4 0.01 0.323 -0.00556 -0.12 -0.0736 -0.629 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 E24 positive control 0.081 -0.248 -9.74 0.082 -0.247 -5.16 -10.5346 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F01 compound treatment 0.362 0.0333 1.31 0.373 0.0444 0.93 1.5837 0.9859 1544313 IFLab1_001871 CC(C)COP(=O)(C(O)c1ccc(cc1)N(C)C)c2ccc(cc2)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F02 compound treatment 0.359 0.0303 1.19 0.354 0.0254 0.53 1.2191 0.934 2066523 IFLab1_001872 FC(F)(F)c1cccc(Nc2ncnc3n(ncc23)c4ccccc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F03 compound treatment 0.329 3.12E-4 0.01 0.326 -0.00256 -0.05 -0.0292 -0.5313 1307066 IFLab1_001873 Cc1ccccc1NC2(CCCCC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F04 compound treatment 0.34 0.0113 0.44 0.322 -0.00656 -0.14 0.2174 0.467 1307373 IFLab1_001874 CCN1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F05 compound treatment 0.343 0.0143 0.56 0.35 0.0214 0.45 0.7151 0.9937 2066524 IFLab1_001875 Brc1cccc(c1)c2nnc(SCC(=O)c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F06 compound treatment 0.318 -0.0107 -0.42 0.333 0.00444 0.09 -0.2315 -0.5379 2066525 IFLab1_001876 CN(C)CCCNc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F07 compound treatment 0.343 0.0143 0.56 0.333 0.00444 0.09 0.4636 0.8128 2066526 IFLab1_001877 CC(C)(C)C(=O)CSc1nnc(o1)c2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F08 compound treatment 0.35 0.0213 0.84 0.336 0.00744 0.16 0.7026 0.8243 1703237 IFLab1_001878 COC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc3CN(C)CCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F09 compound treatment 0.333 0.00431 0.17 0.336 0.00744 0.16 0.2299 0.9991 1740986 IFLab1_001879 Clc1ccccc1c2ccc(o2)C(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F10 compound treatment 0.45 0.121 4.77 0.441 0.112 2.35 5.0365 0.947 1122518 IFLab1_001880 CC(C)N1CCc2c(C(=O)N)c(NC(=O)CCOc3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F11 compound treatment 0.336 0.00731 0.29 0.334 0.00544 0.11 0.2838 0.9177 2066527 IFLab1_001881 CSc1nnc(CNC(=O)c2ccccc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F12 compound treatment 0.332 0.00331 0.13 0.351 0.0224 0.47 0.4241 0.8704 1555617 IFLab1_001882 CCCCn1c(CNC(=O)c2ccc(OC)cc2)nnc1SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F13 compound treatment 0.351 0.0223 0.88 0.35 0.0214 0.45 0.9375 0.9515 2066528 IFLab1_001883 CCC(=O)Nc1nnc(SC)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F14 compound treatment 0.364 0.0353 1.39 0.367 0.0384 0.8 1.5505 0.9663 1545087 IFLab1_001884 Clc1ccc(cc1)c2nnc(NC(=O)Cc3cccs3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F15 compound treatment 0.34 0.0113 0.44 0.339 0.0104 0.22 0.469 0.9464 1476953 IFLab1_001885 CSc1nnc(NC(=O)COc2ccc(Cl)cc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F16 compound treatment 0.344 0.0153 0.6 0.329 4.38E-4 0.01 0.4322 0.7178 1255190 IFLab1_001886 O=C(CCc1ccccc1)Nc2nnc(SCC(=O)N3CCCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F17 compound treatment 0.349 0.0203 0.8 0.326 -0.00256 -0.05 0.5268 0.6581 2066529 IFLab1_001887 CSc1nnc(NC(=O)c2ccc(Cl)cc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F18 compound treatment 0.331 0.00231 0.09 0.327 -0.00156 -0.03 0.0412 0.4261 1145823 IFLab1_001888 COCC(C)Nc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F19 compound treatment 0.345 0.0163 0.64 0.347 0.0184 0.39 0.7263 0.9704 1571608 IFLab1_001889 CC(C)Nc1ncnc2n(ncc12)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F20 compound treatment 0.356 0.0273 1.07 0.359 0.0304 0.64 1.2097 0.9689 2066530 IFLab1_001890 CCOC(=O)c1sc2nc(NC(=O)C)sc2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F21 compound treatment 0.337 0.00831 0.33 0.344 0.0154 0.32 0.4595 1.0 1229721 IFLab1_001891 Cc1ccc(c(C)c1)n2ncc3c(NCC4CCCO4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F22 compound treatment 0.376 0.0473 1.86 0.366 0.0374 0.78 1.8693 0.9261 1390189 IFLab1_001892 Clc1ccc2nc(NC(=O)C3COc4ccccc4O3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F23 mock treatment 0.326 -0.00269 -0.11 0.334 0.00544 0.11 0.0057 0.037 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 F24 positive control 0.082 -0.247 -9.7 0.082 -0.247 -5.16 -10.5068 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G01 compound treatment 0.347 0.0183 0.72 0.349 0.0204 0.43 0.8115 0.9691 2066531 IFLab1_001893 Cc1ccc(o1)C2CC(=O)NC(=C2C#N)SCC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G02 compound treatment 0.331 0.00231 0.09 0.328 -5.62E-4 -0.01 0.056 0.6105 1540328 IFLab1_001894 Cc1ccc(cc1)c2nnc(NC(=O)C3CC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G03 compound treatment 0.341 0.0123 0.48 0.337 0.00844 0.18 0.4672 0.9066 1229379 IFLab1_001895 CCSC1=C(C#N)C(CC(=O)N1)c2cccc(Cl)c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G04 compound treatment 0.353 0.0243 0.96 0.348 0.0194 0.41 0.9636 0.9275 1704234 IFLab1_001896 CCc1nnc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G05 compound treatment 0.348 0.0193 0.76 0.324 -0.00456 -0.1 0.4694 0.6134 1412010 IFLab1_001897 Cc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G06 compound treatment 0.344 0.0153 0.6 0.344 0.0154 0.32 0.6541 0.9574 2066532 IFLab1_001898 NC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G07 compound treatment 0.339 0.0103 0.41 0.345 0.0164 0.34 0.5299 0.9967 1738994 IFLab1_001899 CCC(=O)Nc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G08 compound treatment 0.373 0.0443 1.74 0.364 0.0354 0.74 1.7563 0.9276 1544297 IFLab1_001900 CC(C)(C)C(=O)Nc1ccc(c2nc3ccccc3s2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G09 compound treatment 0.326 -0.00269 -0.11 0.333 0.00444 0.09 -0.0091 -0.0644 1192710 IFLab1_001901 CCOc1ccc(cc1)S(=O)(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G10 compound treatment 0.339 0.0103 0.41 0.342 0.0134 0.28 0.4855 0.984 2066533 IFLab1_001902 CCCc1nc2ccccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G11 compound treatment 0.342 0.0133 0.52 0.346 0.0174 0.36 0.6281 0.9844 1393173 IFLab1_001903 CS(=O)(=O)c1ccc2nc(NC(=O)CCSc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G12 compound treatment 0.332 0.00331 0.13 0.308 -0.0206 -0.43 -0.2122 -0.4719 2066534 IFLab1_001904 CCOC(=O)C(C)Sc1nnc(NC(=O)c2cc(Br)ccc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G13 compound treatment 0.354 0.0253 1.0 0.354 0.0254 0.53 1.0801 0.957 2066535 IFLab1_001905 O=C(Nc1nc(cs1)c2ccc(C#N)cc2)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G14 compound treatment 0.333 0.00431 0.17 0.333 0.00444 0.09 0.1856 0.9598 2066536 IFLab1_001906 CC(C)Sc1nnc(NC(=O)c2ccccc2C(F)(F)F)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G15 compound treatment 0.334 0.00531 0.21 0.34 0.0114 0.24 0.3169 0.9977 1134081 IFLab1_001907 Cc1cc(C)c2nc(NC(=O)CN3C(=O)CCC3=O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G16 compound treatment 0.333 0.00431 0.17 0.339 0.0104 0.22 0.2743 0.9922 2066537 IFLab1_001908 Oc1c(/C=N/c2ncccn2)c(=O)oc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G17 compound treatment 0.319 -0.00969 -0.38 0.349 0.0204 0.43 0.0331 0.0578 1344110 IFLab1_001909 O=C(CN1C(=O)CCC1=O)Nc2sc3CCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G18 compound treatment 0.338 0.00931 0.37 0.329 4.38E-4 0.01 0.2654 0.7246 1590099 IFLab1_001910 Clc1ccc(OC(=O)c2cccs2)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G19 compound treatment 0.343 0.0143 0.56 0.339 0.0104 0.22 0.5524 0.9151 1236688 IFLab1_001911 CN(C)c1ccc(cc1)C(=O)N=c2sc3cc(Cl)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G20 compound treatment 0.336 0.00731 0.29 0.338 0.00944 0.2 0.3429 0.9832 1116313 IFLab1_001912 OC(=O)Cn1c(=S)sc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G21 compound treatment 0.331 0.00231 0.09 0.339 0.0104 0.22 0.2187 0.9246 2066538 IFLab1_001913 Cn1ncc(I)c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G22 compound treatment 0.353 0.0243 0.96 0.355 0.0264 0.55 1.0671 0.9662 1593262 IFLab1_001914 COC(=O)c1ccc(cc1)C(=O)Nc2cccc3c(OC)cccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G23 mock treatment 0.317 -0.0117 -0.46 0.32 -0.00856 -0.18 -0.4516 -0.9157 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 G24 positive control 0.082 -0.247 -9.7 0.082 -0.247 -5.16 -10.5068 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H01 compound treatment 0.359 0.0303 1.19 0.347 0.0184 0.39 1.1156 0.8905 1539174 IFLab1_001915 CC(C)OP(=O)(C(Nc1ccccc1)c2ccccc2)c3ccc(cc3)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H02 compound treatment 0.321 -0.00769 -0.3 0.331 0.00244 0.05 -0.1777 -0.5796 1420157 IFLab1_001916 CCN(CC)c1ncnc2n(ncc12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H03 compound treatment 0.326 -0.00269 -0.11 0.33 0.00144 0.03 -0.0534 -0.4865 1689697 IFLab1_001917 COc1ccccc1NC2(CCCCC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H04 compound treatment 0.325 -0.00369 -0.14 0.338 0.00944 0.2 0.0371 0.1515 1124205 IFLab1_001918 CCC(CO)Nc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H05 compound treatment 0.323 -0.00569 -0.22 0.337 0.00844 0.18 -0.0333 -0.1168 2066539 IFLab1_001919 CCOc1ccc(Cc2nnc(SCC(=O)c3ccc(Cl)cc3)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H06 compound treatment 0.329 3.12E-4 0.01 0.343 0.0144 0.3 0.2223 0.7353 1562161 IFLab1_001920 CCN(CC)CCNc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H07 compound treatment 0.327 -0.00169 -0.07 0.339 0.0104 0.22 0.1075 0.4711 2066540 IFLab1_001921 CCCn1c[n+](CC(=O)C(C)(C)C)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H08 compound treatment 0.326 -0.00269 -0.11 0.356 0.0274 0.57 0.3313 0.5674 1470976 IFLab1_001922 COC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc3CN(CCc13)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H09 compound treatment 0.34 0.0113 0.44 0.344 0.0154 0.32 0.5429 0.9877 1452917 IFLab1_001923 COC(=O)C1=C(C)Nc2ncnn2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H10 compound treatment 0.348 0.0193 0.76 0.342 0.0134 0.28 0.7358 0.9087 1684580 IFLab1_001924 CC(=O)Nc1sc(Cc2ccc3OCOc3c2)c(C)c1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H11 compound treatment 0.341 0.0123 0.48 0.344 0.0154 0.32 0.5707 0.9807 1611826 IFLab1_001925 CCSc1nnc(CNC(=O)c2ccccc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H12 compound treatment 0.325 -0.00369 -0.14 0.323 -0.00556 -0.12 -0.1848 -0.9941 1342725 IFLab1_001926 CCCCn1c(CNC(=O)c2ccc(OC)cc2)nnc1SC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H13 compound treatment 0.343 0.0143 0.56 0.342 0.0134 0.28 0.5968 0.9486 2066541 IFLab1_001927 CSc1nnc(NC(=O)C(C)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H14 compound treatment 0.353 0.0243 0.96 0.358 0.0294 0.62 1.1115 0.9774 1318892 IFLab1_001928 COC(=O)C1=C(CCS1)NC(=O)c2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H15 compound treatment 0.343 0.0143 0.56 0.341 0.0124 0.26 0.582 0.9386 1714879 IFLab1_001929 Clc1ccccc1C(=O)Nc2nnc(SCc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H16 compound treatment 0.313 -0.0157 -0.62 0.312 -0.0166 -0.35 -0.6812 -0.9628 2066542 IFLab1_001930 O=C(CSCc1ccccc1)Nc2nnc(SCC(=O)N3CCCCCC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H17 compound treatment 0.34 0.0113 0.44 0.348 0.0194 0.41 0.6021 0.999 1321105 IFLab1_001931 Fc1cccc(Cl)c1C(=O)Nc2nnc(SCC(=O)N3CCCc4ccccc34)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H18 compound treatment 0.316 -0.0127 -0.5 0.318 -0.0106 -0.22 -0.509 -0.9329 1246268 IFLab1_001932 CC(O)CNc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H19 compound treatment 0.333 0.00431 0.17 0.349 0.0204 0.43 0.4223 0.9179 1334198 IFLab1_001933 Cc1cccc(c1)n2ncc3c(NC(C)(C)C)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H20 compound treatment 0.325 -0.00369 -0.14 0.324 -0.00456 -0.1 -0.17 -0.9795 2066543 IFLab1_001934 CCOC(=O)c1sc(NC(=O)c2ccccc2)c(SC#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H21 compound treatment 0.349 0.0203 0.8 0.353 0.0244 0.51 0.9263 0.9768 1526571 IFLab1_001935 Clc1ccc(cc1)n2ncc3c(Nc4ccccc4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H22 compound treatment 0.365 0.0363 1.43 0.375 0.0464 0.97 1.6967 0.9824 1622380 IFLab1_001936 CSc1nc2ccc(NC(=O)C3COc4ccccc4O3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H23 mock treatment 0.329 3.12E-4 0.01 0.33 0.00144 0.03 0.03 0.922 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 H24 positive control 0.084 -0.245 -9.62 0.085 -0.244 -5.1 -10.4068 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I01 compound treatment 0.351 0.0223 0.88 0.345 0.0164 0.34 0.8636 0.9164 1433444 IFLab1_001937 COC(=O)C1C(C(=C(NC1=O)SC)C#N)c2ccccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I02 compound treatment 0.335 0.00631 0.25 0.336 0.00744 0.16 0.2856 0.9747 1268390 IFLab1_001938 Brc1ccc(cc1)c2nnc(NC(=O)C3CC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I03 compound treatment 0.339 0.0103 0.41 0.345 0.0164 0.34 0.5299 0.9967 2066544 IFLab1_001939 CCOc1ccc(cc1)C2[C@H](C(=O)OC)C(=O)NC(=C2C#N)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I04 compound treatment 0.339 0.0103 0.41 0.342 0.0134 0.28 0.4855 0.984 2066545 IFLab1_001940 CCSc1nnc(NC(=O)c2c(C)onc2c3ccccc3Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I05 compound treatment 0.336 0.00731 0.29 0.344 0.0154 0.32 0.4317 0.9983 1351574 IFLab1_001941 CCSC1=C(C#N)C(C(C#N)C(=O)N1)c2ccccc2OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I06 compound treatment 0.363 0.0343 1.35 0.36 0.0314 0.66 1.4191 0.9455 1251069 IFLab1_001942 CCOC(=O)c1sc2nc(N)c(C#N)c(c3ccc(Cl)cc3)c2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I07 compound treatment 0.35 0.0213 0.84 0.339 0.0104 0.22 0.747 0.8626 1655783 IFLab1_001943 OCC(=O)Nc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I08 compound treatment 0.346 0.0173 0.68 0.358 0.0294 0.62 0.9169 0.9988 1662562 IFLab1_001944 CSc1nc2ccc(NC(=O)c3cc(=O)c4ccccc4o3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I09 compound treatment 0.348 0.0193 0.76 0.348 0.0194 0.41 0.8245 0.9572 2066546 IFLab1_001945 COC(=O)c1cccc2c(Br)ccc(C(=O)OC)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I10 compound treatment 0.343 0.0143 0.56 0.334 0.00544 0.11 0.4784 0.8332 2066547 IFLab1_001946 CCCc1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I11 compound treatment 0.356 0.0273 1.07 0.359 0.0304 0.64 1.2097 0.9689 1244189 IFLab1_001947 O=C(CCc1ccccc1)Nc2nc(cs2)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I12 compound treatment 0.345 0.0163 0.64 0.348 0.0194 0.41 0.7411 0.9759 1421279 IFLab1_001948 CCOC(=O)C(C)Sc1nnc(NC(=O)C2CC2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I13 compound treatment 0.353 0.0243 0.96 0.361 0.0324 0.68 1.1559 0.9859 2066548 IFLab1_001949 O=C(Nc1ccc2OCOc2c1)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I14 compound treatment 0.333 0.00431 0.17 0.316 -0.0126 -0.26 -0.066 -0.211 1169448 IFLab1_001950 CC(C)Sc1nnc(NC(=O)c2cc(Br)ccc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I15 compound treatment 0.337 0.00831 0.33 0.34 0.0114 0.24 0.4003 0.9883 1321566 IFLab1_001951 O=C(CN1C(=O)CCC1=O)Nc2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I16 compound treatment 0.339 0.0103 0.41 0.34 0.0114 0.24 0.456 0.9684 2066549 IFLab1_001952 Cc1cc(C)nc(N/C=C/2\C(=O)Oc3ccccc3C2=O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I17 compound treatment 0.345 0.0163 0.64 0.35 0.0214 0.45 0.7707 0.9847 1599758 IFLab1_001953 Brc1ccc(NC(=O)CN2C(=O)CCC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I18 compound treatment 0.355 0.0263 1.03 0.364 0.0354 0.74 1.2559 0.9867 1699779 IFLab1_001954 c1coc(c1)c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I19 compound treatment 0.337 0.00831 0.33 0.327 -0.00156 -0.03 0.208 0.6332 2066550 IFLab1_001955 Cn1c(=NC(=O)/C=C/c2cccs2)sc3cc(Cl)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I20 compound treatment 0.511 0.182 7.17 0.501 0.172 3.61 7.6202 0.9495 2066551 IFLab1_001956 CN1/C(=C\C=C2C(=O)CC(C)(C)CC2=O)/C(C)(C)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I21 compound treatment 0.358 0.0293 1.15 0.348 0.0194 0.41 1.1026 0.9021 1385511 IFLab1_001957 CCOc1ccc(NC(=O)c2ccccc2NC(=O)c3cccnc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I22 compound treatment 0.33 0.00131 0.05 0.311 -0.0176 -0.37 -0.2234 -0.6019 1606202 IFLab1_001958 COC(=O)c1ccc(cc1)C(=O)Nc2cc(C)on2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I23 mock treatment 0.332 0.00331 0.13 0.337 0.00844 0.18 0.2169 0.9888 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 I24 positive control 0.085 -0.244 -9.58 0.085 -0.244 -5.1 -10.379 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J01 compound treatment 0.343 0.0143 0.56 0.345 0.0164 0.34 0.6411 0.9721 2066552 IFLab1_001959 Fc1ccc(/C=N/n2cnnc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J02 compound treatment 0.329 3.12E-4 0.01 0.332 0.00344 0.07 0.0596 0.8161 1435936 IFLab1_001960 CCN(CC)c1ncnc2n(ncc12)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J03 compound treatment 0.327 -0.00169 -0.07 0.326 -0.00256 -0.05 -0.0848 -0.9944 1540841 IFLab1_001961 COc1ccc(NC2(CCCCC2)C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J04 compound treatment 0.356 0.0273 1.07 0.357 0.0284 0.6 1.1801 0.9612 1429199 IFLab1_001962 COc1cccc(Nc2ncnc3n(ncc23)c4ccccc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J05 compound treatment 0.325 -0.00369 -0.14 0.325 -0.00356 -0.07 -0.1552 -0.9522 2066553 IFLab1_001963 C/N=C(/O)\n1c(nc2ccccc12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J06 compound treatment 0.335 0.00631 0.25 0.329 4.38E-4 0.01 0.182 0.7327 1688897 IFLab1_001964 CCN(c1ccccc1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J07 compound treatment 0.347 0.0183 0.72 0.35 0.0214 0.45 0.8263 0.9741 2066554 IFLab1_001965 CSc1ccc(cc1)c2cn3ccsc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J08 compound treatment 0.512 0.183 7.21 0.515 0.186 3.9 7.8552 0.9585 2066555 IFLab1_001966 CC(C)N1CCc2c(C#N)c(NC(=O)CCc3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J09 compound treatment 0.332 0.00331 0.13 0.338 0.00944 0.2 0.2317 0.9796 1694650 IFLab1_001967 CC1=C(C(c2ccccc2Cl)n3ncnc3N1)C(=O)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J10 compound treatment 0.334 0.00531 0.21 0.347 0.0184 0.39 0.4205 0.9585 2066556 IFLab1_001968 COc1ccc(cc1)C(=O)NCc2nnc(SC(C)C)n2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J11 compound treatment 0.343 0.0143 0.56 0.337 0.00844 0.18 0.5228 0.8864 2066557 IFLab1_001969 O=C(CSc1nnc(CNC(=O)c2ccccc2)n1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J12 compound treatment 0.325 -0.00369 -0.14 0.333 0.00444 0.09 -0.0369 -0.2141 2066558 IFLab1_001970 CCCSc1nnc(CNC(=O)C2(CC3CC4CC(C3)C2)C4)n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J13 compound treatment 0.343 0.0143 0.56 0.345 0.0164 0.34 0.6411 0.9721 2066559 IFLab1_001971 CC(C)Sc1nnc(NC(=O)C(C)C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J14 compound treatment 0.346 0.0173 0.68 0.354 0.0254 0.53 0.8577 0.9926 1599393 IFLab1_001972 COC(=O)C1=C(CCS1)NC(=O)CSCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J15 compound treatment 0.338 0.00931 0.37 0.331 0.00244 0.05 0.295 0.7979 1542441 IFLab1_001973 CCCSc1nnc(NC(=O)c2ccccc2Br)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J16 compound treatment 0.37 0.0413 1.62 0.361 0.0324 0.68 1.6286 0.9251 1319496 IFLab1_001974 COc1ccc(CC(=O)Nc2nnc(SCc3ccccc3)s2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J17 compound treatment 0.336 0.00731 0.29 0.338 0.00944 0.2 0.3429 0.9832 2066560 IFLab1_001975 CSc1nnc(NC(=O)c2ccco2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J18 compound treatment 0.348 0.0193 0.76 0.34 0.0114 0.24 0.7062 0.887 2066561 IFLab1_001976 CN(C)CCCNc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J19 compound treatment 0.349 0.0203 0.8 0.345 0.0164 0.34 0.808 0.9291 1338944 IFLab1_001977 C=CCNc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J20 compound treatment 0.351 0.0223 0.88 0.355 0.0264 0.55 1.0115 0.9753 2066562 IFLab1_001978 COc1cc(OC)cc(c1)C(=O)N=c2sc3cc(C)cc(C)c3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J21 compound treatment 0.35 0.0213 0.84 0.348 0.0194 0.41 0.8801 0.9449 1289588 IFLab1_001979 Cc1ccccc1Nc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J22 compound treatment 0.343 0.0143 0.56 0.348 0.0194 0.41 0.6855 0.9873 1443554 IFLab1_001980 Cc1nc2cc(NC(=O)C3COc4ccccc4O3)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J23 mock treatment 0.328 -6.88E-4 -0.03 0.327 -0.00156 -0.03 -0.0422 -0.9955 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 J24 positive control 0.086 -0.243 -9.54 0.087 -0.242 -5.06 -10.3216 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K01 compound treatment 0.352 0.0233 0.92 0.353 0.0244 0.51 1.0097 0.962 2066563 IFLab1_001981 CC(=C)CSC1=C(C#N)C(CC(=O)N1)c2sccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K02 compound treatment 0.33 0.00131 0.05 0.325 -0.00356 -0.07 -0.0162 -0.1789 1162356 IFLab1_001982 COc1ccc(Cl)cc1C(=O)Nc2nnc(s2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K03 compound treatment 0.334 0.00531 0.21 0.338 0.00944 0.2 0.2873 0.9996 2066564 IFLab1_001983 NC(=O)CSC1=C(C#N)C(C(C(=O)c2cccs2)C(O)(N1)C(F)(F)F)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K04 compound treatment 0.355 0.0263 1.03 0.353 0.0244 0.51 1.0931 0.9472 1620885 IFLab1_001984 CCSc1nnc(NC(=O)c2ccc3ccccc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K05 compound treatment 0.341 0.0123 0.48 0.327 -0.00156 -0.03 0.3192 0.6578 1713691 IFLab1_001985 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K06 compound treatment 0.37 0.0413 1.62 0.339 0.0104 0.22 1.303 0.795 2066565 IFLab1_001986 COC(=O)c1sc2nc(N)c(C#N)c(c3ccc(Cl)cc3)c2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K07 compound treatment 0.358 0.0293 1.15 0.359 0.0304 0.64 1.2653 0.9609 1417357 IFLab1_001987 Brc1ccc2[nH]c(=O)c(N3CCCCC3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K08 compound treatment 0.383 0.0543 2.14 0.369 0.0404 0.85 2.1084 0.9179 1512636 IFLab1_001988 Cn1c(=NC(=O)c2cc(=O)c3ccccc3o2)sc4cc(Br)ccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K09 compound treatment 0.358 0.0293 1.15 0.355 0.0264 0.55 1.2061 0.9435 1160121 IFLab1_001989 CCOc1nc(c(Cl)s1)S(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K10 compound treatment 0.344 0.0153 0.6 0.341 0.0124 0.26 0.6098 0.9296 1145304 IFLab1_001990 CCCc1nc2ccccc2n1CC(=O)N(C(C)C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K11 compound treatment 0.365 0.0363 1.43 0.365 0.0364 0.76 1.5487 0.9568 1666697 IFLab1_001991 CC(=O)Nc1ccc2nc(NC(=O)CCc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K12 compound treatment 0.387 0.0583 2.29 0.383 0.0544 1.14 2.4267 0.9479 1298019 IFLab1_001992 COc1ccc(Cl)cc1C(=O)Nc2nnc(SCC(=O)c3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K13 compound treatment 0.39 0.0613 2.41 0.372 0.0434 0.91 2.3474 0.9111 2066566 IFLab1_001993 O=C(Nc1sc2CCCCc2c1C#N)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K14 compound treatment 0.36 0.0313 1.23 0.37 0.0414 0.87 1.4837 0.9853 1171242 IFLab1_001994 COc1cccc(OC)c1C(=O)Nc2nnc(SC)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K15 compound treatment 0.35 0.0213 0.84 0.338 0.00944 0.2 0.7322 0.8505 1413908 IFLab1_001995 Cc1ccc2n(C)c(=NC(=O)CN3C(=O)CCC3=O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K16 compound treatment 0.35 0.0213 0.84 0.349 0.0204 0.43 0.8949 0.9513 2066567 IFLab1_001996 FC(F)(F)c1cccc(N/C=C/2\C(=O)Oc3ccccc3C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K17 compound treatment 0.348 0.0193 0.76 0.35 0.0214 0.45 0.8541 0.9685 1284270 IFLab1_001997 O=S(=O)(N1CCN(Cc2ccccc2)CC1)c3cccc4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K18 compound treatment 0.382 0.0533 2.1 0.367 0.0384 0.8 2.051 0.9135 1654918 IFLab1_001998 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N2CCN(CCO)CC2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K19 compound treatment 0.349 0.0203 0.8 0.355 0.0264 0.55 0.9559 0.9839 1139214 IFLab1_001999 Cc1cccc(NC(=O)CCSc2ccccc2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K20 compound treatment 0.332 0.00331 0.13 0.343 0.0144 0.3 0.3057 0.9293 1057475 IFLab1_002000 OCc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K21 compound treatment 0.335 0.00631 0.25 0.346 0.0174 0.36 0.4335 0.9824 2066568 IFLab1_002001 Clc1cccc(/C=C/C(=O)Nc2cc3ccccc3oc2=O)c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K22 compound treatment 0.346 0.0173 0.68 0.36 0.0314 0.66 0.9465 0.9999 2066569 IFLab1_002002 COC(=O)c1ccc(cc1)C(=O)/C(=C\2/Nc3ccccc3S2)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K23 mock treatment 0.333 0.00431 0.17 0.324 -0.00456 -0.1 0.0524 0.2692 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 K24 positive control 0.087 -0.242 -9.5 0.087 -0.242 -5.06 -10.2938 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L01 compound treatment 0.411 0.0823 3.24 0.37 0.0414 0.87 2.9016 0.866 2066570 IFLab1_002003 CS(=O)(=O)c1ccc(/C=C/c2ccc(Cl)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L02 compound treatment 0.32 -0.00869 -0.34 0.324 -0.00456 -0.1 -0.309 -0.8714 1639021 IFLab1_002004 CCN(CC)c1ncnc2n(ncc12)c3ccc(C)cc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L03 compound treatment 0.327 -0.00169 -0.07 0.335 0.00644 0.13 0.0483 0.3219 1273051 IFLab1_002005 O=C(N1CCN(CC1)C(C#N)c2ccco2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L04 compound treatment 0.33 0.00131 0.05 0.332 0.00344 0.07 0.0874 0.9867 1323830 IFLab1_002006 COc1ccc(CNc2ncnc3n(ncc23)c4ccccc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L05 compound treatment 0.351 0.0223 0.88 0.358 0.0294 0.62 1.0559 0.985 2066571 IFLab1_002007 COc1ccccc1/C=C/2\C(=Nc3ccccc23)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L06 compound treatment 0.324 -0.00469 -0.18 0.326 -0.00256 -0.05 -0.1682 -0.8765 1719787 IFLab1_002008 CC1CC(C)CN(C1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L07 compound treatment 0.327 -0.00169 -0.07 0.33 0.00144 0.03 -0.0256 -0.352 1432193 IFLab1_002009 COC(=O)Nc1ccc(SCC(=O)N(C(C)C)c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L08 compound treatment 0.33 0.00131 0.05 0.348 0.0194 0.41 0.3241 0.7905 2066572 IFLab1_002010 CC(C)(C)C(=O)Nc1sc2CN(Cc3ccccc3)CCc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L09 compound treatment 0.503 0.174 6.85 0.549 0.22 4.61 8.1081 0.9814 1183269 IFLab1_002011 Fc1ccc(cc1)C(CC(=O)c2ccncc2)SCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L10 compound treatment 0.338 0.00931 0.37 0.35 0.0214 0.45 0.5761 0.9949 1561883 IFLab1_002012 COc1ccc(cc1)C(=O)NCc2nnc(SC)n2Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L11 compound treatment 0.33 0.00131 0.05 0.327 -0.00156 -0.03 0.0134 0.2188 1657887 IFLab1_002013 CCCSc1nnc(CNC(=O)c2cccc(F)c2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L12 compound treatment 0.373 0.0443 1.74 0.383 0.0544 1.14 2.0375 0.9788 1537959 IFLab1_002014 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)CCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L13 compound treatment 0.333 0.00431 0.17 0.352 0.0234 0.49 0.4667 0.8993 1615904 IFLab1_002015 CCC(CC)C(=O)Nc1nnc(SCC(=O)Nc2ccc(F)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L14 compound treatment 0.351 0.0223 0.88 0.356 0.0274 0.57 1.0263 0.9789 1717888 IFLab1_002016 COC(=O)C1=C(CCS1)NC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L15 compound treatment 0.367 0.0383 1.51 0.359 0.0304 0.64 1.5156 0.9267 1193481 IFLab1_002017 Cc1ccc(cc1)C(=O)Nc2nnc(SCc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L16 compound treatment 0.357 0.0283 1.11 0.353 0.0244 0.51 1.1487 0.9377 2066573 IFLab1_002018 O=C(CSCc1ccccc1)Nc2nnc(SCc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L17 compound treatment 0.371 0.0423 1.66 0.366 0.0374 0.78 1.7303 0.941 2066574 IFLab1_002019 O=C(Nc1nnc(SCc2ccccc2)s1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L18 compound treatment 0.346 0.0173 0.68 0.347 0.0184 0.39 0.7541 0.9638 1714750 IFLab1_002020 CC(C)C(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L19 compound treatment 0.358 0.0293 1.15 0.371 0.0424 0.89 1.4429 0.9917 1345426 IFLab1_002021 C(Nc1ncnc2n(ncc12)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L20 compound treatment 0.347 0.0183 0.72 0.325 -0.00356 -0.07 0.4564 0.6305 1270721 IFLab1_002022 O=C(N1CCN(CC1)c2nc3ccccc3s2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L21 compound treatment 0.375 0.0463 1.82 0.359 0.0304 0.64 1.738 0.9009 1319044 IFLab1_002023 Cc1cccc(Nc2ncnc3n(ncc23)c4ccccc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L22 compound treatment 0.359 0.0303 1.19 0.368 0.0394 0.83 1.4263 0.9839 1250717 IFLab1_002024 COc1ccc(cc1)c2csc(NC(=O)C3COc4ccccc4O3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L23 mock treatment 0.328 -6.88E-4 -0.03 0.32 -0.00856 -0.18 -0.1458 -0.8047 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 L24 positive control 0.088 -0.241 -9.46 0.088 -0.241 -5.03 -10.2512 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M01 compound treatment 0.334 0.00531 0.21 0.329 4.38E-4 0.01 0.1542 0.7374 2066575 IFLab1_002025 Cc1ccsc1C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M02 compound treatment 0.338 0.00931 0.37 0.335 0.00644 0.13 0.3542 0.9078 1521578 IFLab1_002026 Clc1ccccc1c2nnc(NC(=O)C3CC3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M03 compound treatment 0.335 0.00631 0.25 0.335 0.00644 0.13 0.2708 0.9588 2066576 IFLab1_002027 CSC1=C(C#N)C(C(C(=O)c2cccs2)C(O)(N1)C(F)(F)F)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M04 compound treatment 0.328 -6.88E-4 -0.03 0.326 -0.00256 -0.05 -0.057 -0.9497 1717378 IFLab1_002028 CCSc1nnc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M05 compound treatment 0.358 0.0293 1.15 0.354 0.0254 0.53 1.1913 0.9384 1367096 IFLab1_002029 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M06 compound treatment 0.362 0.0333 1.31 0.365 0.0364 0.76 1.4653 0.9669 2066577 IFLab1_002030 Cc1ccc(cc1)c2c(C#N)c(N)nc(SCC=C)c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M07 compound treatment 0.331 0.00231 0.09 0.329 4.38E-4 0.01 0.0708 0.7744 1203190 IFLab1_002031 Cc1ccc2[nH]c(=O)c(N3CCCCC3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M08 compound treatment 0.386 0.0573 2.25 0.39 0.0614 1.29 2.5025 0.9646 1351022 IFLab1_002032 CCOc1ccc2nc(NC(=O)CCc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M09 compound treatment 0.358 0.0293 1.15 0.371 0.0424 0.89 1.4429 0.9917 1401467 IFLab1_002033 CC(=O)Nc1nc2sc(C)c(C)c2c(=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M10 compound treatment 0.336 0.00731 0.29 0.333 0.00444 0.09 0.269 0.8902 1648432 IFLab1_002034 CCc1nc2ccccc2n1CC(=O)N(C(C)C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M11 compound treatment 0.349 0.0203 0.8 0.351 0.0224 0.47 0.8967 0.9679 1605456 IFLab1_002035 CCc1ccccc1NC(=O)c2ccc(cc2)S(=O)(=O)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M12 compound treatment 0.361 0.0323 1.27 0.379 0.0504 1.06 1.6447 0.9958 1283829 IFLab1_002036 COc1ccc(CC(=O)Nc2nnc(SCC(=O)c3ccccc3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M13 compound treatment 0.352 0.0233 0.92 0.356 0.0274 0.57 1.0541 0.9746 2066578 IFLab1_002037 O=C(Nc1sc2CCCc2c1C#N)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M14 compound treatment 0.33 0.00131 0.05 0.35 0.0214 0.45 0.3537 0.7833 1024180 IFLab1_002038 OC(c1ccccc1)c2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M15 compound treatment 0.327 -0.00169 -0.07 0.35 0.0214 0.45 0.2703 0.596 1472063 IFLab1_002039 Clc1ccc(NC(=O)CN2C(=O)CCC2=O)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M16 compound treatment 0.356 0.0273 1.07 0.353 0.0244 0.51 1.1209 0.9424 1534214 IFLab1_002040 Fc1ccc(cc1)C(=O)Oc2ccc(Cl)c3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M17 compound treatment 0.345 0.0163 0.64 0.353 0.0244 0.51 0.8151 0.9937 2066579 IFLab1_002041 Brc1ccc(s1)C(=O)Nc2nc(cs2)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M18 compound treatment 0.29 -0.0387 -1.52 0.303 -0.0256 -0.53 -1.4538 -0.9016 1235906 IFLab1_002042 OCc1cc(=O)c(O)c(o1)C(Nc2ccccn2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M19 compound treatment 0.359 0.0303 1.19 0.363 0.0344 0.72 1.3523 0.971 2066580 IFLab1_002043 O=C(COC(=O)/C=C/c1cccs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M20 compound treatment 0.348 0.0193 0.76 0.356 0.0274 0.57 0.9429 0.9905 1141707 IFLab1_002044 CC(C)Oc1ccc(cc1)C(=O)N=c2sc3cc(Cl)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M21 compound treatment 0.329 3.12E-4 0.01 0.341 0.0124 0.26 0.1927 0.7397 2066581 IFLab1_002045 Cc1cc(nn1CC(=O)N)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M22 compound treatment 0.347 0.0183 0.72 0.36 0.0314 0.66 0.9743 0.999 1118672 IFLab1_002046 COC(=O)c1ccc(cc1)C(=O)Nc2ccc3n(c(C)nc3c2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M23 mock treatment 0.331 0.00231 0.09 0.324 -0.00456 -0.1 -0.0032 -0.0244 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 M24 positive control 0.091 -0.238 -9.35 0.09 -0.239 -4.99 -10.1382 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N01 compound treatment 0.349 0.0203 0.8 0.345 0.0164 0.34 0.808 0.9291 1367393 IFLab1_002047 CC(=C1C(=O)c2ccccc2C1=O)NCc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N02 compound treatment 0.323 -0.00569 -0.22 0.329 4.38E-4 0.01 -0.1517 -0.6776 1346381 IFLab1_002048 CCCN(CCC)c1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N03 compound treatment 0.328 -6.88E-4 -0.03 0.326 -0.00256 -0.05 -0.057 -0.9497 1741714 IFLab1_002049 N#CC1(CCCCC1)NCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N04 compound treatment 0.354 0.0253 1.0 0.337 0.00844 0.18 0.8286 0.8198 1291416 IFLab1_002050 COc1ccccc1CNc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N05 compound treatment 0.334 0.00531 0.21 0.332 0.00344 0.07 0.1986 0.8988 2066582 IFLab1_002051 O/C(=C/Sc1nnc(Cc2ccccc2)o1)/c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N06 compound treatment 0.338 0.00931 0.37 0.335 0.00644 0.13 0.3542 0.9078 1426062 IFLab1_002052 CC1CN(CC(C)O1)c2ncnc3n(ncc23)c4cccc(C)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N07 compound treatment 0.344 0.0153 0.6 0.342 0.0134 0.28 0.6246 0.9399 2066583 IFLab1_002053 COC(=O)Nc1ccc(SCC(=O)Nc2ccc(C)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N08 compound treatment 0.499 0.17 6.7 0.49 0.161 3.38 7.1238 0.9498 2066584 IFLab1_002054 CC(C)N1CCc2c(C#N)c(NC(=O)C(C)(C)C)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N09 compound treatment 0.336 0.00731 0.29 0.314 -0.0146 -0.3 -0.0122 -0.0291 1195559 IFLab1_002055 Fc1ccc(cc1)C(Nc2ccccn2)c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N10 compound treatment 0.343 0.0143 0.56 0.338 0.00944 0.2 0.5376 0.9014 1426396 IFLab1_002056 COc1ccc(cc1)C(=O)NCc2nnc(SC(C)C)n2Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N11 compound treatment 0.341 0.0123 0.48 0.356 0.0274 0.57 0.7483 0.9964 1589739 IFLab1_002057 CCSc1nnc(CNC(=O)c2cccc(OC)c2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N12 compound treatment 0.37 0.0413 1.62 0.35 0.0214 0.45 1.4658 0.8698 1323956 IFLab1_002058 COc1ccccc1c2nnc(NC(=O)CSCc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N13 compound treatment 0.357 0.0283 1.11 0.361 0.0324 0.68 1.2671 0.9719 1545951 IFLab1_002059 CC(C)CC(=O)Nc1nnc(SCc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N14 compound treatment 0.358 0.0293 1.15 0.36 0.0314 0.66 1.2801 0.9646 2066585 IFLab1_002060 CSc1nnc(NC(=O)/C=C\c2ccc3OCOc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N15 compound treatment 0.346 0.0173 0.68 0.352 0.0234 0.49 0.8281 0.9871 2066586 IFLab1_002061 CSc1nnc(NC(=O)c2ccc(F)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N16 compound treatment 0.343 0.0143 0.56 0.341 0.0124 0.26 0.582 0.9386 2066587 IFLab1_002062 COc1ccc(/C=C/C(=O)Nc2nnc(SCc3ccccc3)s2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N17 compound treatment 0.343 0.0143 0.56 0.349 0.0204 0.43 0.7003 0.9908 2066588 IFLab1_002063 CSc1nnc(NC(=O)c2cccs2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N18 compound treatment 0.346 0.0173 0.68 0.347 0.0184 0.39 0.7541 0.9638 1380308 IFLab1_002064 Cc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N19 compound treatment 0.338 0.00931 0.37 0.323 -0.00556 -0.12 0.1766 0.4596 1724334 IFLab1_002065 Cc1ccc(c(C)c1)n2ncc3c(NC4CCCCC4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N20 compound treatment 0.344 0.0153 0.6 0.34 0.0114 0.24 0.595 0.9183 1122906 IFLab1_002066 CCOC(=O)c1sc(NC(=O)COc2ccccc2)c(SC#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N21 compound treatment 0.336 0.00731 0.29 0.337 0.00844 0.18 0.3282 0.9726 1438816 IFLab1_002067 Cc1ccc(Nc2ncnc3n(ncc23)c4ccccc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N22 compound treatment 0.333 0.00431 0.17 0.336 0.00744 0.16 0.2299 0.9991 2066589 IFLab1_002068 O=C(Nc1nc(cs1)c2cccs2)c3ccc4ncsc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N23 mock treatment 0.336 0.00731 0.29 0.324 -0.00456 -0.1 0.1358 0.4482 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 N24 positive control 0.092 -0.237 -9.31 0.09 -0.239 -4.99 -10.1104 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O01 compound treatment 0.332 0.00331 0.13 0.328 -5.62E-4 -0.01 0.0838 0.6406 2066590 IFLab1_002069 COC(=O)[C@H]1C(C(=C(NC1=O)SCC=C)C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O02 compound treatment 0.329 3.12E-4 0.01 0.326 -0.00256 -0.05 -0.0292 -0.5313 1131201 IFLab1_002070 Cc1nnc(NC(=O)c2ccc3ccccc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O03 compound treatment 0.326 -0.00269 -0.11 0.324 -0.00456 -0.1 -0.1422 -0.9987 1560450 IFLab1_002071 COC(=O)CSC1=C(C#N)C(C(C#N)C(=O)N1)c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O04 compound treatment 0.341 0.0123 0.48 0.329 4.38E-4 0.01 0.3488 0.7204 1630046 IFLab1_002072 CC(C)c1nnc(NC(=O)c2ccc3ccccc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O05 compound treatment 0.33 0.00131 0.05 0.321 -0.00756 -0.16 -0.0754 -0.4531 1660891 IFLab1_002073 COc1ccc(cc1)c2nnc(SCC(=O)O)n2CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O06 compound treatment 0.373 0.0443 1.74 0.362 0.0334 0.7 1.7268 0.9197 2066591 IFLab1_002074 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)/C=C/c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O07 compound treatment 0.342 0.0133 0.52 0.344 0.0154 0.32 0.5985 0.9731 1699053 IFLab1_002075 CCN(CC)c1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O08 compound treatment 0.347 0.0183 0.72 0.354 0.0254 0.53 0.8855 0.989 1606282 IFLab1_002076 Cc1sc2nc(SCC(=O)N3CCCC3)[nH]c(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O09 compound treatment 0.346 0.0173 0.68 0.341 0.0124 0.26 0.6654 0.913 2066592 IFLab1_002077 C=CCSc1nc2sc3CCCCc3c2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O10 compound treatment 0.355 0.0263 1.03 0.349 0.0204 0.43 1.034 0.9236 2066593 IFLab1_002078 CCc1nc2ccccc2n1CC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O11 compound treatment 0.341 0.0123 0.48 0.329 4.38E-4 0.01 0.3488 0.7204 1127904 IFLab1_002079 CCc1ccccc1NC(=O)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O12 compound treatment 0.377 0.0483 1.9 0.387 0.0584 1.22 2.2079 0.9773 1493243 IFLab1_002080 CCCSc1nnc(NC(=O)Cc2ccc(OC)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O13 compound treatment 0.412 0.0833 3.28 0.407 0.0784 1.64 3.4769 0.949 1203259 IFLab1_002081 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O14 compound treatment 0.343 0.0143 0.56 0.348 0.0194 0.41 0.6855 0.9873 1402101 IFLab1_002082 CC(NC(=O)c1ccccc1)C(O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O15 compound treatment 0.339 0.0103 0.41 0.352 0.0234 0.49 0.6335 0.9955 1628010 IFLab1_002083 Cc1ccc(NC(=O)CN2C(=O)CCC2=O)c(c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O16 compound treatment 0.356 0.0273 1.07 0.357 0.0284 0.6 1.1801 0.9612 1495979 IFLab1_002084 COc1ccc(cc1OC)C(=O)Oc2ccc(Cl)c3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O17 compound treatment 0.356 0.0273 1.07 0.359 0.0304 0.64 1.2097 0.9689 1266836 IFLab1_002085 O=C(CCOc1ccccc1)Nc2nc(cs2)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O18 compound treatment 0.543 0.214 8.43 0.482 0.153 3.21 8.2287 0.9125 1915215 IFLab1_002086 CN1/C(=C\C=N\c2cccc(c2)C(=O)O)/C(C)(C)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O19 compound treatment 0.341 0.0123 0.48 0.343 0.0144 0.3 0.5559 0.9742 2066594 IFLab1_002087 O=C(OCc1ccc2OCOc2c1)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O20 compound treatment 0.348 0.0193 0.76 0.348 0.0194 0.41 0.8245 0.9572 1297842 IFLab1_002088 COc1cccc(OC)c1C(=O)N=c2sc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O21 compound treatment 0.357 0.0283 1.11 0.363 0.0344 0.72 1.2967 0.9778 2066595 IFLab1_002089 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCC#N)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O22 compound treatment 0.342 0.0133 0.52 0.347 0.0184 0.39 0.6429 0.9887 1453344 IFLab1_002090 O=C(CSc1nc2ccccc2s1)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O23 mock treatment 0.335 0.00631 0.25 0.332 0.00344 0.07 0.2264 0.876 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 O24 positive control 0.094 -0.235 -9.23 0.093 -0.236 -4.93 -10.0104 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P01 compound treatment 0.348 0.0193 0.76 0.342 0.0134 0.28 0.7358 0.9087 2066596 IFLab1_002091 COc1ccc(/C=C/C(=C2C(=O)c3ccccc3C2=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P02 compound treatment 0.338 0.00931 0.37 0.335 0.00644 0.13 0.3542 0.9078 1287937 IFLab1_002092 CN(C1CCCCC1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P03 compound treatment 0.351 0.0223 0.88 0.352 0.0234 0.49 0.9671 0.9623 1374478 IFLab1_002093 COc1ccc(cc1)C(C#N)N2CCN(CC2)C(C#N)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P04 compound treatment 0.381 0.0523 2.06 0.354 0.0254 0.53 1.8308 0.8617 1474382 IFLab1_002094 C(Nc1ncnc2n(ncc12)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P05 compound treatment 0.394 0.0653 2.57 0.387 0.0584 1.22 2.6805 0.9424 2066597 IFLab1_002095 CCOc1ccc(/C=C\2/C(=Nc3ccccc23)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P06 compound treatment 0.381 0.0523 2.06 0.369 0.0404 0.85 2.0528 0.923 1265467 IFLab1_002096 Cc1ccc(c(C)c1)n2ncc3c(NCc4cccs4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P07 compound treatment 0.376 0.0473 1.86 0.374 0.0454 0.95 1.9877 0.9515 1649963 IFLab1_002097 COc1ccnc(Nc2ccc(C)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P08 compound treatment 0.408 0.0793 3.12 0.406 0.0774 1.62 3.3509 0.9535 1151052 IFLab1_002098 CN1CCc2c(C(=O)N)c(NC(=O)c3cc(Cl)sc3Cl)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P09 compound treatment 0.371 0.0423 1.66 0.372 0.0434 0.91 1.8191 0.9596 1597260 IFLab1_002099 Cc1occc(=O)c1OC(=O)c2ccc(cc2)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P10 compound treatment 0.391 0.0623 2.45 0.387 0.0584 1.22 2.5971 0.9485 1130732 IFLab1_002100 COc1ccc(cc1)C(=O)NCc2nnc(SC)n2CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P11 compound treatment 0.376 0.0473 1.86 0.364 0.0354 0.74 1.8398 0.9187 1217156 IFLab1_002101 CSc1nnc(CNC(=O)Cc2ccccc2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P12 compound treatment 0.381 0.0523 2.06 0.375 0.0464 0.97 2.1415 0.9414 1737840 IFLab1_002102 COc1ccc(OC)c(c1)c2nnc(NC(=O)Cc3cccs3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P13 compound treatment 0.378 0.0493 1.94 0.367 0.0384 0.8 1.9398 0.9241 1627526 IFLab1_002103 CC(C)(C)C(=O)Nc1nnc(SCc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P14 compound treatment 0.368 0.0393 1.55 0.363 0.0344 0.72 1.6025 0.9397 1467867 IFLab1_002104 CSc1nnc(NC(=O)c2cc3ccccc3oc2=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P15 compound treatment 0.369 0.0403 1.59 0.371 0.0424 0.89 1.7487 0.9625 1131969 IFLab1_002105 CC(C)Sc1nnc(NC(=O)c2ccc(F)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P16 compound treatment 0.373 0.0443 1.74 0.369 0.0404 0.85 1.8303 0.945 1642669 IFLab1_002106 Fc1ccc(CSc2nnc(NC(=O)CCc3ccccc3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P17 compound treatment 0.361 0.0323 1.27 0.37 0.0414 0.87 1.5115 0.9827 2066598 IFLab1_002107 CC(C)Sc1nnc(NC(=O)c2cccs2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P18 compound treatment 0.38 0.0513 2.02 0.375 0.0464 0.97 2.1137 0.9439 1153759 IFLab1_002108 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P19 compound treatment 0.364 0.0353 1.39 0.369 0.0404 0.85 1.5801 0.9718 1297256 IFLab1_002109 Clc1ccc(cc1)n2ncc3c(NCc4ccco4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P20 compound treatment 0.367 0.0383 1.51 0.362 0.0334 0.7 1.5599 0.9392 1399814 IFLab1_002110 O=C(CCOc1ccccc1)N2CCN(CC2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P21 compound treatment 0.363 0.0343 1.35 0.363 0.0344 0.72 1.4635 0.9569 1486928 IFLab1_002111 CCc1ccccc1Nc2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P22 compound treatment 0.355 0.0263 1.03 0.356 0.0274 0.57 1.1375 0.9614 2066599 IFLab1_002112 Cc1sc(NC(=O)c2ccc3ncsc3c2)nc1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P23 mock treatment 0.332 0.00331 0.13 0.341 0.0124 0.26 0.2761 0.9488 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1417 P24 positive control 0.098 -0.231 -9.07 0.097 -0.232 -4.85 -9.84 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A01 compound treatment 0.358 0.0276 1.08 0.355 0.0256 0.54 1.1455 0.9474 1635158 IFLab1_002113 CCOC(=O)Cc1csc(NC(=O)c2ccc3ncsc3c2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A02 compound treatment 0.329 -0.00144 -0.06 0.337 0.00763 0.16 0.0729 0.4304 1610130 IFLab1_002114 Cc1nnc(NC(=O)CSc2c[nH]c3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A03 compound treatment 0.326 -0.00444 -0.17 0.324 -0.00537 -0.11 -0.2029 -0.9774 1165598 IFLab1_002115 Cc1cccc(NC(=O)c2ccc3CCCCc3c2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A04 compound treatment 0.334 0.00356 0.14 0.334 0.00463 0.1 0.1675 0.9837 2066600 IFLab1_002116 CC(Oc1ccccc1)C(=O)Nc2ccc(cc2)n3nncc3c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A05 compound treatment 0.343 0.0126 0.49 0.349 0.0196 0.41 0.6397 0.9958 1573765 IFLab1_002117 O=C(Nc1ccc2sccc2c1)C3COc4ccccc4O3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A06 compound treatment 0.335 0.00456 0.18 0.323 -0.00637 -0.13 0.0325 0.1454 1249570 IFLab1_002118 Cc1cc(C)n2cc(CN3CCOCC3)nc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A07 compound treatment 0.334 0.00356 0.14 0.32 -0.00937 -0.2 -0.0397 -0.1646 1492235 IFLab1_002119 CCCC(=O)Nc1c2CS(=O)(=O)Cc2nn1c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A08 compound treatment 0.332 0.00156 0.06 0.331 0.00163 0.03 0.0675 0.9611 1570935 IFLab1_002120 COCC(C)n1c(=O)c2ccccc2c3ccccc3c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A09 compound treatment 0.366 0.0356 1.4 0.336 0.00663 0.14 1.0867 0.7734 1733826 IFLab1_002121 CCC(C(=O)Nc1c2CSCc2nn1c3ccc(F)cc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A10 compound treatment 0.342 0.0116 0.45 0.356 0.0266 0.56 0.7154 0.9949 2066601 IFLab1_002122 CN1CCc2c(OCC(=O)N3CCC(Cc4ccccc4)CC3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A11 compound treatment 0.334 0.00356 0.14 0.325 -0.00437 -0.09 0.0343 0.205 2066602 IFLab1_002123 O=C(CSC1=NN2CCCC(=O)N=C2S1)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A12 compound treatment 0.325 -0.00544 -0.21 0.333 0.00363 0.08 -0.0975 -0.4299 2066603 IFLab1_002124 CCN1CCc2c(OCc3ccc(Cl)cc3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A13 compound treatment 0.335 0.00456 0.18 0.328 -0.00137 -0.03 0.1065 0.5862 1161551 IFLab1_002125 Cc1nnc(NC(=O)CSc2cn(Cc3ccccc3)c4ccccc24)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A14 compound treatment 0.315 -0.0154 -0.61 0.321 -0.00837 -0.18 -0.5531 -0.8755 2066604 IFLab1_002126 CC(C)Oc1cccc2C(=O)N(Cc3ccccc3)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A15 compound treatment 0.328 -0.00244 -0.1 0.337 0.00763 0.16 0.0451 0.2421 1341623 IFLab1_002127 COc1ccc(CCNC(=O)CSc2cn(C)c3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A16 compound treatment 0.353 0.0226 0.89 0.332 0.00263 0.05 0.6661 0.7495 2066605 IFLab1_002128 O=C(COc1cccc2C(=O)N(Cc3cccnc3)CCc12)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A17 compound treatment 0.327 -0.00344 -0.14 0.333 0.00363 0.08 -0.0419 -0.2705 1575537 IFLab1_002129 CCn1cc(SCC(=O)NCc2ccco2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A18 compound treatment 0.329 -0.00144 -0.06 0.349 0.0196 0.41 0.2504 0.6041 1429546 IFLab1_002130 Cc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A19 compound treatment 0.344 0.0136 0.53 0.332 0.00263 0.05 0.4159 0.7758 2066606 IFLab1_002131 Fc1ccc(CSc2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A20 compound treatment 0.329 -0.00144 -0.06 0.33 6.25E-4 0.01 -0.0307 -0.5295 1168181 IFLab1_002132 Fc1ccc(cc1)C2N(CC(=O)Nc3ccc(F)cc23)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A21 compound treatment 0.324 -0.00644 -0.25 0.345 0.0156 0.33 0.0522 0.1263 1383288 IFLab1_002133 O=C(CSc1c[nH]c2ccccc12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A22 compound treatment 0.338 0.00756 0.3 0.321 -0.00837 -0.18 0.0863 0.2501 1698240 IFLab1_002134 CCCCC1CCC(CC1)C(=O)Nc2c3CS(=O)Cc3nn2c4ccccc4C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A23 mock treatment 0.322 -0.00844 -0.33 0.321 -0.00837 -0.18 -0.3585 -0.9555 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 A24 positive control 0.079 -0.251 -9.89 0.079 -0.25 -5.24 -10.6953 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B01 compound treatment 0.344 0.0136 0.53 0.353 0.0236 0.49 0.7266 0.9993 1132477 IFLab1_002135 Cc1cccc(c1C)n2nc3CS(=O)Cc3c2NC(=O)COc4ccc(Cl)cc4Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B02 compound treatment 0.319 -0.0114 -0.45 0.333 0.00363 0.08 -0.2643 -0.5796 2066607 IFLab1_002136 CCCSc1nc2CCSc2c(=O)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B03 compound treatment 0.334 0.00356 0.14 0.332 0.00263 0.05 0.1379 0.9165 2066608 IFLab1_002137 CC(C)Sc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B04 compound treatment 0.343 0.0126 0.49 0.348 0.0186 0.39 0.6249 0.9931 1599701 IFLab1_002138 CC(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B05 compound treatment 0.314 -0.0164 -0.65 0.329 -3.75E-4 -0.01 -0.4625 -0.7156 2066609 IFLab1_002139 CC(=O)Oc1c(Sc2ccccc2)c(C)nn1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B06 compound treatment 0.328 -0.00244 -0.1 0.358 0.0286 0.6 0.3558 0.5865 2066610 IFLab1_002140 CCOc1ccccc1C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B07 compound treatment 0.334 0.00356 0.14 0.357 0.0276 0.58 0.5078 0.8537 1337346 IFLab1_002141 NC(=O)CSc1c([nH]c2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B08 compound treatment 0.337 0.00656 0.26 0.352 0.0226 0.47 0.5172 0.9593 2066611 IFLab1_002142 O=C(NCCSc1c[nH]c2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B09 compound treatment 0.358 0.0276 1.08 0.352 0.0226 0.47 1.1011 0.9311 1501564 IFLab1_002143 CC1CC(CC(C)(C)C1)Nc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B10 compound treatment 0.345 0.0146 0.57 0.338 0.00863 0.18 0.5325 0.887 2066612 IFLab1_002144 Cc1[nH]c2ccccc2c1SCCNC(=O)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B11 compound treatment 0.34 0.00956 0.38 0.334 0.00463 0.1 0.3343 0.8611 1666807 IFLab1_002145 CC(C)CNc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B12 compound treatment 0.344 0.0136 0.53 0.351 0.0216 0.45 0.6971 0.9967 2066613 IFLab1_002146 CCC(=O)NCCSc1c([nH]c2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B13 compound treatment 0.338 0.00756 0.3 0.328 -0.00137 -0.03 0.1899 0.6357 1204379 IFLab1_002147 CCN(C1CCCCC1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B14 compound treatment 0.347 0.0166 0.65 0.329 -3.75E-4 -0.01 0.4549 0.6985 2066614 IFLab1_002148 Cn1c(CNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B15 compound treatment 0.341 0.0106 0.42 0.332 0.00263 0.05 0.3325 0.7937 1740866 IFLab1_002149 CCOC(=O)C(CC)Sc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B16 compound treatment 0.344 0.0136 0.53 0.336 0.00663 0.14 0.4751 0.8623 2066615 IFLab1_002150 CCCn1c(CNC(=O)c2cccc(C)c2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B17 compound treatment 0.346 0.0156 0.61 0.344 0.0146 0.31 0.6491 0.9487 2066616 IFLab1_002151 CN(CCNc1ncnc2[nH]cnc12)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B18 compound treatment 0.329 -0.00144 -0.06 0.333 0.00363 0.08 0.0137 0.1445 2066617 IFLab1_002152 CCCCn1c(CNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B19 compound treatment 0.341 0.0106 0.42 0.331 0.00163 0.03 0.3177 0.7625 2066618 IFLab1_002153 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B20 compound treatment 0.341 0.0106 0.42 0.35 0.0206 0.43 0.5988 0.9998 2066619 IFLab1_002154 CC(C)(C)C(=O)NCc1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B21 compound treatment 0.338 0.00756 0.3 0.346 0.0166 0.35 0.4563 0.9969 2066620 IFLab1_002155 COC(=O)C(C)Sc1nc2CCSc2c(=O)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B22 compound treatment 0.338 0.00756 0.3 0.329 -3.75E-4 -0.01 0.2047 0.6882 2066621 IFLab1_002156 Cc1cccc(c1)C(=O)NCc2nc3ccccc3n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B23 mock treatment 0.333 0.00256 0.1 0.33 6.25E-4 0.01 0.0805 0.7923 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 B24 positive control 0.078 -0.252 -9.93 0.08 -0.249 -5.22 -10.7083 -0.9549 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C01 compound treatment 0.34 0.00956 0.38 0.34 0.0106 0.22 0.4231 0.9686 1633953 IFLab1_002157 Fc1cccc(NC(=O)C2COc3ccccc3O2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C02 compound treatment 0.321 -0.00944 -0.37 0.344 0.0146 0.31 -0.046 -0.0956 1252358 IFLab1_002158 Cc1cc(NC(=O)CSc2c[nH]c3ccccc23)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C03 compound treatment 0.322 -0.00844 -0.33 0.375 0.0456 0.95 0.4405 0.4359 1433727 IFLab1_002159 Cc1cccc(NC(=O)C2COc3ccccc3O2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C04 compound treatment 0.344 0.0136 0.53 0.402 0.0726 1.52 1.4517 0.9013 1504829 IFLab1_002160 Fc1ccc(cc1)C(=O)Nc2ccc(cc2)n3nncc3c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C05 compound treatment 0.316 -0.0144 -0.57 0.39 0.0606 1.27 0.4957 0.3566 1633628 IFLab1_002161 COc1ccc2n(C)c(=NC(=O)C3COc4ccccc4O3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C06 compound treatment 0.334 0.00356 0.14 0.408 0.0786 1.65 1.2625 0.7645 1737527 IFLab1_002162 Cc1cc(C)n2c(Br)c(CN3CCC4(CC3)OCCO4)nc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C07 compound treatment 0.327 -0.00344 -0.14 0.43 0.101 2.11 1.3934 0.6604 2066622 IFLab1_002163 CC(=O)Nc1c2CS(=O)(=O)Cc2nn1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C08 compound treatment 0.35 0.0196 0.77 0.44 0.111 2.31 2.1808 0.894 1629891 IFLab1_002164 O=c1n(Cc2ccco2)c(=O)c3ccccc3c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C09 compound treatment 0.353 0.0226 0.89 0.471 0.142 2.96 2.7229 0.8802 1614228 IFLab1_002165 Fc1ccc(cc1)n2nc3CSCc3c2NC(=O)COc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C10 compound treatment 0.333 0.00256 0.1 0.442 0.113 2.36 1.7378 0.7367 2066623 IFLab1_002166 CN1CCc2c(OCC(=O)NC3CCCCC3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C11 compound treatment 0.342 0.0116 0.45 0.401 0.0716 1.5 1.3813 0.8819 2066624 IFLab1_002167 O=C(CSC1=NN2CCCC(=O)N=C2S1)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C12 compound treatment 0.344 0.0136 0.53 0.407 0.0776 1.62 1.5257 0.8924 2066625 IFLab1_002168 CCN1CCc2c(OCC(=O)N3CCC(Cc4ccccc4)CC3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C13 compound treatment 0.339 0.00856 0.34 0.387 0.0576 1.21 1.0907 0.8712 1512964 IFLab1_002169 Cn1cc(SCC(=O)N2CCCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C14 compound treatment 0.326 -0.00444 -0.17 0.382 0.0526 1.1 0.6553 0.5877 2066626 IFLab1_002170 CCOC(=O)COc1cccc2C(=O)N(Cc3ccccc3)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C15 compound treatment 0.335 0.00456 0.18 0.38 0.0506 1.06 0.876 0.8152 1604129 IFLab1_002171 Cn1cc(SCC(=O)NCc2ccco2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C16 compound treatment 0.345 0.0146 0.57 0.38 0.0506 1.06 1.154 0.9583 1668735 IFLab1_002172 O=C(CSCC(=O)N1CCCC1)Nc2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C17 compound treatment 0.342 0.0116 0.45 0.383 0.0536 1.12 1.115 0.9209 1597456 IFLab1_002173 CCn1cc(SCC(=O)Nc2nccs2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C18 compound treatment 0.341 0.0106 0.42 0.372 0.0426 0.89 0.9244 0.9395 1399135 IFLab1_002174 CCCC(=O)N1CC(=O)Nc2ccc(Br)cc2C1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C19 compound treatment 0.326 -0.00444 -0.17 0.382 0.0526 1.1 0.6553 0.5877 2066627 IFLab1_002175 Fc1cccc(CSc2c[nH]c3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C20 compound treatment 0.338 0.00756 0.3 0.382 0.0526 1.1 0.989 0.867 1343528 IFLab1_002176 CC(C)(C)n1nc2CS(=O)Cc2c1NC(=O)CC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C21 compound treatment 0.336 0.00556 0.22 0.335 0.00563 0.12 0.2379 0.9578 1368429 IFLab1_002177 Cc1cccc(NC(=O)CSc2c[nH]c3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C22 compound treatment 0.337 0.00656 0.26 0.326 -0.00337 -0.07 0.1325 0.4953 1125236 IFLab1_002178 O=C(Cc1ccccc1)Nc2c3CS(=O)Cc3nn2c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C23 mock treatment 0.334 0.00356 0.14 0.325 -0.00437 -0.09 0.0343 0.205 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 C24 positive control 0.08 -0.25 -9.85 0.078 -0.251 -5.26 -10.6823 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D01 compound treatment 0.348 0.0176 0.69 0.354 0.0246 0.52 0.8527 0.9896 2066628 IFLab1_002179 CCn1c(=NC(=O)c2ccc(cc2)S(=O)(=O)N(C)C)sc3cc(Cl)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D02 compound treatment 0.337 0.00656 0.26 0.336 0.00663 0.14 0.2805 0.9576 2066629 IFLab1_002180 CC(C)Sc1nc2CCSc2c(=O)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D03 compound treatment 0.344 0.0136 0.53 0.406 0.0766 1.6 1.5109 0.8941 2066630 IFLab1_002181 CCC(C)Sc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D04 compound treatment 0.358 0.0276 1.08 0.414 0.0846 1.77 2.0185 0.9722 1160659 IFLab1_002182 CCOC(=O)CSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccc(C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D05 compound treatment 0.335 0.00456 0.18 0.394 0.0646 1.35 1.0831 0.7939 1575575 IFLab1_002183 COCC(=O)Oc1c(Sc2ccc(C)cc2)c(C)nn1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D06 compound treatment 0.343 0.0126 0.49 0.415 0.0856 1.79 1.6163 0.8696 2066631 IFLab1_002184 O=C(NCCSc1c[nH]c2ccccc12)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D07 compound treatment 0.361 0.0306 1.2 0.449 0.12 2.5 2.6198 0.9435 1439475 IFLab1_002185 CC1=C(C(c2ccccc2)n3nc(SCc4ccccc4)nc3N1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D08 compound treatment 0.349 0.0186 0.73 0.445 0.116 2.42 2.227 0.8812 1986922 IFLab1_002186 CC(C)C(=O)NCCSc1c[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D09 compound treatment 0.344 0.0136 0.53 0.398 0.0686 1.44 1.3925 0.909 1088782 IFLab1_002187 C(Cc1ccccc1)Nc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D10 compound treatment 0.333 0.00256 0.1 0.438 0.109 2.27 1.6786 0.7377 2066632 IFLab1_002188 Cc1[nH]c2ccccc2c1SCCNC(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D11 compound treatment 0.344 0.0136 0.53 0.412 0.0826 1.73 1.5997 0.8841 1222884 IFLab1_002189 CC(O)CNc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D12 compound treatment 0.345 0.0146 0.57 0.409 0.0796 1.67 1.5831 0.8985 2066633 IFLab1_002190 COc1ccc(cc1)c2[nH]c3ccccc3c2SCCNC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D13 compound treatment 0.338 0.00756 0.3 0.41 0.0806 1.69 1.4033 0.8191 1329314 IFLab1_002191 C1CCCN(CC1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D14 compound treatment 0.333 0.00256 0.1 0.432 0.103 2.15 1.5898 0.7395 2066634 IFLab1_002192 Cn1c(CNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D15 compound treatment 0.331 5.63E-4 0.02 0.42 0.0906 1.9 1.3566 0.7153 2066635 IFLab1_002193 CCOC(=O)C(C)(C)Sc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D16 compound treatment 0.343 0.0126 0.49 0.433 0.104 2.17 1.8826 0.8465 2066636 IFLab1_002194 CC(C)n1c(CNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D17 compound treatment 0.339 0.00856 0.34 0.43 0.101 2.11 1.727 0.8099 2066637 IFLab1_002195 CCN(c1cccc(C)c1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D18 compound treatment 0.335 0.00456 0.18 0.396 0.0666 1.39 1.1127 0.7916 2066638 IFLab1_002196 CCCCn1c(CNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D19 compound treatment 0.341 0.0106 0.42 0.389 0.0596 1.25 1.1759 0.8942 2066639 IFLab1_002197 NC(=O)CSc1nc2CCSc2c(=O)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D20 compound treatment 0.342 0.0116 0.45 0.37 0.0406 0.85 0.9226 0.957 2066640 IFLab1_002198 Fc1ccccc1Cn2c(CNC(=O)Cc3ccccc3)nc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D21 compound treatment 0.339 0.00856 0.34 0.346 0.0166 0.35 0.4841 0.9999 2066641 IFLab1_002199 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)OCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D22 compound treatment 0.34 0.00956 0.38 0.342 0.0126 0.26 0.4527 0.9851 2066642 IFLab1_002200 C=CCn1c(CNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D23 mock treatment 0.335 0.00456 0.18 0.329 -3.75E-4 -0.01 0.1213 0.6755 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 D24 positive control 0.081 -0.249 -9.81 0.08 -0.249 -5.22 -10.6249 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E01 compound treatment 0.338 0.00756 0.3 0.343 0.0136 0.29 0.4119 0.9998 1527773 IFLab1_002201 O=C(Nc1nccs1)c2ccc3CCCCc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E02 compound treatment 0.333 0.00256 0.1 0.346 0.0166 0.35 0.3172 0.8759 2066643 IFLab1_002202 CC(C)(C)c1cnnn1c2ccc(NC(=O)COc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E03 compound treatment 0.334 0.00356 0.14 0.388 0.0586 1.23 0.9665 0.7828 1374536 IFLab1_002203 O=C(N1CCN(CC1)c2ccccc2)c3ccc4CCCCc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E04 compound treatment 0.368 0.0376 1.48 0.433 0.104 2.17 2.5777 0.9825 1643731 IFLab1_002204 COc1ccc(cc1)C(=O)Nc2ccc(cc2)n3nncc3c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E05 compound treatment 0.345 0.0146 0.57 0.417 0.0876 1.83 1.7015 0.8857 1359418 IFLab1_002205 CCN1CCc2c(C(=O)N)c(NC(=O)c3ccc4CCCCc4c3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E06 compound treatment 0.343 0.0126 0.49 0.404 0.0746 1.56 1.4535 0.8874 1228490 IFLab1_002206 COc1ccc(cc1)N2CCN(Cc3nc4nc(C)cc(C)n4c3Br)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E07 compound treatment 0.341 0.0106 0.42 0.429 0.0996 2.08 1.7678 0.8316 2066644 IFLab1_002207 Clc1ccc(cc1)n2nc3CS(=O)(=O)Cc3c2NC(=O)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E08 compound treatment 0.358 0.0276 1.08 0.493 0.164 3.42 3.1875 0.8875 2066645 IFLab1_002208 Brc1ccc(CN2CCc3c(OCC(=O)N4CCOCC4)cccc3C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E09 compound treatment 0.34 0.00956 0.38 0.469 0.14 2.92 2.3319 0.7916 2066646 IFLab1_002209 Cc1cccc(c1C)n2nc3CSCc3c2NC(=O)/C=C\c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E10 compound treatment 0.363 0.0326 1.28 0.47 0.141 2.94 2.9861 0.9305 2066647 IFLab1_002210 CN1CCc2c(OCC(=O)N3CCc4ccccc34)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E11 compound treatment 0.346 0.0156 0.61 0.439 0.11 2.29 2.0548 0.8655 2066648 IFLab1_002211 O=C(CSC1=NN2CCCC(=O)N=C2S1)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E12 compound treatment 0.35 0.0196 0.77 0.44 0.111 2.31 2.1808 0.894 2066649 IFLab1_002212 CCN1CCc2c(OCC(=O)N3CCCc4ccccc34)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E13 compound treatment 0.35 0.0196 0.77 0.433 0.104 2.17 2.0772 0.9028 1274679 IFLab1_002213 Cn1cc(SCC(=O)NC2CCCCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E14 compound treatment 0.338 0.00756 0.3 0.449 0.12 2.5 1.9804 0.7856 2066650 IFLab1_002214 CC1CCN(CC1)C(=O)COc2cccc3C(=O)N(Cc4ccccc4)CCc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E15 compound treatment 0.349 0.0186 0.73 0.463 0.134 2.8 2.4933 0.8628 1546893 IFLab1_002215 Cn1cc(SCC(=O)Nc2nccs2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E16 compound treatment 0.343 0.0126 0.49 0.459 0.13 2.71 2.2673 0.8223 1267123 IFLab1_002216 O=C(CSCC(=O)N1CCOCC1)Nc2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E17 compound treatment 0.342 0.0116 0.45 0.454 0.125 2.61 2.1656 0.818 1512881 IFLab1_002217 CCSc1nnc(NC(=O)CSc2cn(CC)c3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E18 compound treatment 0.319 -0.0114 -0.45 0.396 0.0666 1.39 0.6679 0.4559 1192525 IFLab1_002218 CC(C)CC(=O)N1CC(=O)Nc2ccc(Cl)cc2C1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E19 compound treatment 0.332 0.00156 0.06 0.394 0.0646 1.35 0.9997 0.7385 1431821 IFLab1_002219 O=C(CSc1c[nH]c2ccccc12)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E20 compound treatment 0.337 0.00656 0.26 0.376 0.0466 0.98 0.8724 0.8644 1522936 IFLab1_002220 Cc1ccc(cc1)n2nc3CS(=O)Cc3c2NC(=O)C4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E21 compound treatment 0.323 -0.00744 -0.29 0.354 0.0246 0.52 0.1576 0.266 1248786 IFLab1_002221 COc1ccc(NC(=O)CSc2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E22 compound treatment 0.335 0.00456 0.18 0.334 0.00463 0.1 0.1953 0.9581 1196087 IFLab1_002222 COc1ccc(cc1)n2nc3CS(=O)Cc3c2NC(=O)c4cccc(F)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E23 mock treatment 0.322 -0.00844 -0.33 0.331 0.00163 0.03 -0.2105 -0.6313 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 E24 positive control 0.081 -0.249 -9.81 0.081 -0.248 -5.2 -10.6101 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F01 compound treatment 0.345 0.0146 0.57 0.342 0.0126 0.26 0.5917 0.9383 2066651 IFLab1_002223 CCn1c(=NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)sc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F02 compound treatment 0.332 0.00156 0.06 0.333 0.00363 0.08 0.0971 0.9945 2066652 IFLab1_002224 Clc1ccc(cc1)n2c(SCC(=O)NCCc3ccccc3)nc4CCSc4c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F03 compound treatment 0.331 5.63E-4 0.02 0.37 0.0406 0.85 0.6168 0.7253 2066653 IFLab1_002225 CC(C)CSc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F04 compound treatment 0.363 0.0326 1.28 0.428 0.0986 2.06 2.3647 0.9736 1401085 IFLab1_002226 COC(=O)C(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1c4cc(C)cc(C)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F05 compound treatment 0.328 -0.00244 -0.1 0.376 0.0466 0.98 0.6221 0.6346 2066654 IFLab1_002227 CC(=O)Oc1c(Sc2ccccc2)c(C)nn1C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F06 compound treatment 0.337 0.00656 0.26 0.432 0.103 2.15 1.701 0.7864 2066655 IFLab1_002228 COc1ccc(/C=C/C(=O)NCCSc2c[nH]c3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F07 compound treatment 0.325 -0.00544 -0.21 0.406 0.0766 1.6 0.9827 0.6075 1116063 IFLab1_002229 N(c1ccccc1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F08 compound treatment 0.351 0.0206 0.81 0.457 0.128 2.67 2.4602 0.8817 2066656 IFLab1_002230 O=C(NCCSc1c[nH]c2ccccc12)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F09 compound treatment 0.318 -0.0124 -0.49 0.439 0.11 2.29 1.2763 0.5441 1433115 IFLab1_002231 Cc1ccc(CNc2ncnc3[nH]cnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F10 compound treatment 0.354 0.0236 0.93 0.46 0.131 2.73 2.588 0.8967 2066657 IFLab1_002232 Cc1[nH]c2ccccc2c1SCCNC(=O)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F11 compound treatment 0.345 0.0146 0.57 0.45 0.121 2.52 2.1898 0.846 1515739 IFLab1_002233 C1CCC(C1)Nc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F12 compound treatment 0.32 -0.0104 -0.41 0.455 0.126 2.63 1.5687 0.5896 2066658 IFLab1_002234 CCC(=O)NCCSc1c([nH]c2ccccc12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F13 compound treatment 0.354 0.0236 0.93 0.452 0.123 2.57 2.4696 0.9052 1116026 IFLab1_002235 C1CCN(C1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F14 compound treatment 0.348 0.0176 0.69 0.465 0.136 2.84 2.4951 0.8542 1986747 IFLab1_002236 CCn1c(CNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F15 compound treatment 0.323 -0.00744 -0.29 0.455 0.126 2.63 1.6521 0.6246 1025691 IFLab1_002237 CC(Sc1ncnc2[nH]cnc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F16 compound treatment 0.356 0.0256 1.01 0.466 0.137 2.86 2.7323 0.9016 2066659 IFLab1_002238 CCC(=O)NCc1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F17 compound treatment 0.345 0.0146 0.57 0.441 0.112 2.34 2.0566 0.8551 2066660 IFLab1_002239 CCN(c1ccc(CC)cc1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F18 compound treatment 0.325 -0.00544 -0.21 0.417 0.0876 1.83 1.1454 0.6205 2066661 IFLab1_002240 CC(=O)NCc1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F19 compound treatment 0.349 0.0186 0.73 0.401 0.0716 1.5 1.5759 0.9453 2066662 IFLab1_002241 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F20 compound treatment 0.341 0.0106 0.42 0.381 0.0516 1.08 1.0576 0.9137 2066663 IFLab1_002242 CC(C)Cn1c(CNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F21 compound treatment 0.344 0.0136 0.53 0.365 0.0356 0.75 0.9042 0.9865 2066664 IFLab1_002243 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F22 compound treatment 0.339 0.00856 0.34 0.356 0.0266 0.56 0.632 0.9709 2066665 IFLab1_002244 CCCC(=O)NCc1nc2ccccc2n1CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F23 mock treatment 0.327 -0.00344 -0.14 0.332 0.00263 0.05 -0.0567 -0.3888 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 F24 positive control 0.082 -0.248 -9.77 0.081 -0.248 -5.2 -10.5823 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G01 compound treatment 0.362 0.0316 1.24 0.345 0.0156 0.33 1.1087 0.8639 1529122 IFLab1_002245 COc1cccc(NC(=O)c2ccc3CCCCc3c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G02 compound treatment 0.34 0.00956 0.38 0.343 0.0136 0.29 0.4675 0.9907 1264034 IFLab1_002246 COc1ccc(cc1)C(=O)Nc2ccc(cc2)n3nncc3C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G03 compound treatment 0.345 0.0146 0.57 0.394 0.0646 1.35 1.3611 0.9268 1737761 IFLab1_002247 NC(=O)c1c(NC(=O)C2COc3ccccc3O2)sc4CCCCc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G04 compound treatment 0.33 -4.37E-4 -0.02 0.397 0.0676 1.42 0.9885 0.6985 1611845 IFLab1_002248 O=C(Nc1ccc(cc1)n2nncc2c3ccccc3)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G05 compound treatment 0.361 0.0306 1.2 0.445 0.116 2.42 2.5606 0.9478 1578795 IFLab1_002249 CN1CCc2c(C(=O)N)c(NC(=O)c3ccc4ncsc4c3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G06 compound treatment 0.345 0.0146 0.57 0.405 0.0756 1.58 1.5239 0.9055 1503991 IFLab1_002250 O=C(CSc1cn(CCNC(=O)c2ccccc2)c3ccccc13)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G07 compound treatment 0.344 0.0136 0.53 0.419 0.0896 1.88 1.7033 0.8735 2066666 IFLab1_002251 CC(C)(C)C(=O)Nc1c2CS(=O)(=O)Cc2nn1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G08 compound treatment 0.322 -0.00844 -0.33 0.422 0.0926 1.94 1.136 0.5777 2066667 IFLab1_002252 COc1cccc2C(=O)N(C)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G09 compound treatment 0.34 0.00956 0.38 0.446 0.117 2.44 1.9916 0.8065 2066668 IFLab1_002253 O=C1CCCN2N=C(SCc3ccccc3)SC2=N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G10 compound treatment 0.329 -0.00144 -0.06 0.479 0.15 3.13 2.1741 0.6942 2066669 IFLab1_002254 CN1CCc2c(OCC(=O)Nc3ccccc3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G11 compound treatment 0.34 0.00956 0.38 0.436 0.107 2.23 1.8436 0.8148 1988980 IFLab1_002255 CC(C)SC1=NN2CCCC(=O)N=C2S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G12 compound treatment 0.341 0.0106 0.42 0.47 0.141 2.94 2.3745 0.799 2066670 IFLab1_002256 CCN1CCc2c(OCC(=O)Nc3ccccc3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G13 compound treatment 0.338 0.00756 0.3 0.443 0.114 2.38 1.8916 0.7894 1711507 IFLab1_002257 Cn1cc(SCC(=O)N2CCc3ccccc23)c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G14 compound treatment 0.343 0.0126 0.49 0.468 0.139 2.9 2.4005 0.8158 2066671 IFLab1_002258 O=C(COc1cccc2C(=O)N(Cc3ccccc3)CCc12)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G15 compound treatment 0.339 0.00856 0.34 0.45 0.121 2.52 2.023 0.7944 1700924 IFLab1_002259 Cc1cc(NC(=O)CSc2cn(C)c3ccccc23)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G16 compound treatment 0.319 -0.0114 -0.45 0.458 0.129 2.69 1.5853 0.5809 1624721 IFLab1_002260 CC1CCCCN1C(=O)CSCC(=O)Nc2nc(cs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G17 compound treatment 0.34 0.00956 0.38 0.454 0.125 2.61 2.1099 0.8008 1575716 IFLab1_002261 CCCn1cc(SCC(=O)NC2CCCCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G18 compound treatment 0.321 -0.00944 -0.37 0.424 0.0946 1.98 1.1378 0.5648 1550535 IFLab1_002262 Clc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)c4ccc(Br)o4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G19 compound treatment 0.336 0.00556 0.22 0.417 0.0876 1.83 1.4512 0.7859 1246056 IFLab1_002263 O=C(CSc1c[nH]c2ccccc12)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G20 compound treatment 0.337 0.00656 0.26 0.395 0.0656 1.37 1.1535 0.8255 1243084 IFLab1_002264 Clc1cccc(c1)n2nc3CS(=O)Cc3c2NC(=O)C4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G21 compound treatment 0.33 -4.37E-4 -0.02 0.37 0.0406 0.85 0.589 0.6927 1195249 IFLab1_002265 CCOc1ccc(NC(=O)CSc2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G22 compound treatment 0.355 0.0246 0.97 0.351 0.0216 0.45 1.0029 0.9403 1386808 IFLab1_002266 COc1cccc(c1)C(=O)Nc2c3CS(=O)Cc3nn2c4ccc(C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G23 mock treatment 0.332 0.00156 0.06 0.334 0.00463 0.1 0.1119 0.9759 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 G24 positive control 0.082 -0.248 -9.77 0.081 -0.248 -5.2 -10.5823 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H01 compound treatment 0.349 0.0186 0.73 0.363 0.0336 0.7 1.0136 0.9998 2066672 IFLab1_002267 CCn1c(=NC(=O)c2ccc(cc2)S(=O)(=O)N(CC=C)CC=C)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H02 compound treatment 0.345 0.0146 0.57 0.341 0.0116 0.24 0.5769 0.9273 2066673 IFLab1_002268 CCC(C)Sc1nc2CCSc2c(=O)n1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H03 compound treatment 0.351 0.0206 0.81 0.392 0.0626 1.31 1.4983 0.9731 2066674 IFLab1_002269 O=c1[nH]c(SCc2ccccc2)nc3n(ncc13)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H04 compound treatment 0.345 0.0146 0.57 0.397 0.0676 1.42 1.4055 0.9207 1232933 IFLab1_002270 CCOC(=O)CSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H05 compound treatment 0.339 0.00856 0.34 0.392 0.0626 1.31 1.1647 0.8608 1719331 IFLab1_002271 Cc1[nH]c2ccccc2c1SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H06 compound treatment 0.351 0.0206 0.81 0.416 0.0866 1.81 1.8535 0.9338 2066675 IFLab1_002272 O=C(NCCSc1c[nH]c2ccccc12)C3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H07 compound treatment 0.338 0.00756 0.3 0.426 0.0966 2.02 1.64 0.8025 1716215 IFLab1_002273 Cc1ccccc1Nc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H08 compound treatment 0.355 0.0246 0.97 0.464 0.135 2.82 2.6749 0.8982 2066676 IFLab1_002274 O=C(NCCSc1c[nH]c2ccccc12)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H09 compound treatment 0.348 0.0176 0.69 0.431 0.102 2.13 1.992 0.8909 1011397 IFLab1_002275 OCCNc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H10 compound treatment 0.34 0.00956 0.38 0.507 0.178 3.72 2.8942 0.7747 2066677 IFLab1_002276 Cc1[nH]c2ccccc2c1SCCNC(=O)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H11 compound treatment 0.34 0.00956 0.38 0.463 0.134 2.8 2.2431 0.795 1504774 IFLab1_002277 C(Nc1ncnc2[nH]cnc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H12 compound treatment 0.345 0.0146 0.57 0.489 0.16 3.34 2.7669 0.8164 2066678 IFLab1_002278 CC(=O)NCCSc1c([nH]c2ccccc12)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H13 compound treatment 0.346 0.0156 0.61 0.48 0.151 3.15 2.6615 0.8289 1215993 IFLab1_002279 CC1CC(C)CN(C1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H14 compound treatment 0.342 0.0116 0.45 0.462 0.133 2.78 2.2839 0.8121 2066679 IFLab1_002280 CCC(=O)NCc1nc2ccccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H15 compound treatment 0.343 0.0126 0.49 0.47 0.141 2.94 2.4301 0.8144 1660279 IFLab1_002281 Cc1cccc(CSc2ncnc3[nH]cnc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H16 compound treatment 0.347 0.0166 0.65 0.47 0.141 2.94 2.5413 0.8432 2066680 IFLab1_002282 CCCCn1c(CNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H17 compound treatment 0.348 0.0176 0.69 0.459 0.13 2.71 2.4063 0.8597 2066681 IFLab1_002283 CCCN(c1ccc(OCC)cc1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H18 compound treatment 0.317 -0.0134 -0.53 0.443 0.114 2.38 1.3077 0.5369 2066682 IFLab1_002284 Cc1ccccc1Cn2c(CNC(=O)C(C)(C)C)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H19 compound treatment 0.334 0.00356 0.14 0.439 0.11 2.29 1.7212 0.7489 2066683 IFLab1_002285 CSc1nc2CCSc2c(=O)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H20 compound treatment 0.341 0.0106 0.42 0.387 0.0576 1.21 1.1463 0.8988 2066684 IFLab1_002286 CCC(=O)NCc1nc2ccccc2n1CC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H21 compound treatment 0.339 0.00856 0.34 0.384 0.0546 1.14 1.0463 0.8781 2066685 IFLab1_002287 CCSc1nc2CCSc2c(=O)n1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H22 compound treatment 0.323 -0.00744 -0.29 0.364 0.0346 0.72 0.3056 0.3911 2066686 IFLab1_002288 CC(=C)Cn1c(CNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H23 mock treatment 0.334 0.00356 0.14 0.328 -0.00137 -0.03 0.0787 0.5504 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 H24 positive control 0.084 -0.246 -9.69 0.082 -0.247 -5.18 -10.5119 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I01 compound treatment 0.346 0.0156 0.61 0.346 0.0166 0.35 0.6787 0.9642 1273039 IFLab1_002289 CCOC(=O)c1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I02 compound treatment 0.35 0.0196 0.77 0.35 0.0206 0.43 0.8491 0.9627 2066687 IFLab1_002290 CCOc1ccccc1C(=O)Nc2ccc(cc2)n3nncc3C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I03 compound treatment 0.345 0.0146 0.57 0.385 0.0556 1.16 1.228 0.9466 1441041 IFLab1_002291 CC1CN(CC(C)O1)C(=O)c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I04 compound treatment 0.36 0.0296 1.16 0.414 0.0846 1.77 2.0741 0.9791 1452546 IFLab1_002292 O=C(Nc1ccc(cc1)n2nncc2c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I05 compound treatment 0.345 0.0146 0.57 0.417 0.0876 1.83 1.7015 0.8857 1459497 IFLab1_002293 CCCCC1CCC(CC1)C(=O)Nc2c3CS(=O)(=O)Cc3nn2C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I06 compound treatment 0.375 0.0446 1.75 0.411 0.0816 1.71 2.4467 0.9999 1453256 IFLab1_002294 O=C(CSc1cn(CCNC(=O)c2ccccc2)c3ccccc13)NCc4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I07 compound treatment 0.358 0.0276 1.08 0.427 0.0976 2.04 2.2109 0.956 1388827 IFLab1_002295 Fc1ccc(cc1)n2nc3CS(=O)(=O)Cc3c2NC(=O)CCC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I08 compound treatment 0.367 0.0366 1.44 0.451 0.122 2.55 2.8162 0.9634 2066688 IFLab1_002296 CCCOc1cccc2C(=O)N(C)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I09 compound treatment 0.354 0.0236 0.93 0.457 0.128 2.67 2.5436 0.8998 2066689 IFLab1_002297 CCOC(=O)CSC1=NN2CCCC(=O)N=C2S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I10 compound treatment 0.375 0.0446 1.75 0.509 0.18 3.76 3.8969 0.9396 2066690 IFLab1_002298 CN1CCc2c(OCC(=O)NCc3ccco3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I11 compound treatment 0.369 0.0386 1.52 0.525 0.196 4.09 3.9668 0.9087 2066691 IFLab1_002299 O=C(CSC1=NN2CCCC(=O)N=C2S1)OCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I12 compound treatment 0.353 0.0226 0.89 0.484 0.155 3.24 2.9153 0.8689 2066692 IFLab1_002300 CCN1CCc2c(OCC(=O)NCc3ccco3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I13 compound treatment 0.33 -4.37E-4 -0.02 0.458 0.129 2.69 1.8911 0.7026 1570021 IFLab1_002301 Cn1cc(SCC(=O)N2CCCc3ccccc23)c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I14 compound treatment 0.351 0.0206 0.81 0.481 0.152 3.17 2.8153 0.8598 2066693 IFLab1_002302 O=C(COc1cccc2C(=O)N(Cc3ccccc3)CCc12)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I15 compound treatment 0.329 -0.00144 -0.06 0.464 0.135 2.82 1.9521 0.6928 1196611 IFLab1_002303 CCn1cc(SCC(=O)N2CCOCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I16 compound treatment 0.321 -0.00944 -0.37 0.473 0.144 3.01 1.8629 0.6151 1651192 IFLab1_002304 CC1CCCN(C1)C(=O)CSCC(=O)Nc2nc(cs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I17 compound treatment 0.35 0.0196 0.77 0.46 0.131 2.73 2.4767 0.8722 1710188 IFLab1_002305 CCCn1cc(SCC(=O)NCc2ccco2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I18 compound treatment 0.351 0.0206 0.81 0.44 0.111 2.31 2.2086 0.9007 1308271 IFLab1_002306 Clc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I19 compound treatment 0.35 0.0196 0.77 0.453 0.124 2.59 2.3732 0.8793 1445814 IFLab1_002307 O=C(CSc1c[nH]c2ccccc12)N3CCN(CC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I20 compound treatment 0.35 0.0196 0.77 0.434 0.105 2.19 2.092 0.9015 1275791 IFLab1_002308 Cc1ccc(cc1)n2nc3CS(=O)Cc3c2NC(=O)CCC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I21 compound treatment 0.351 0.0206 0.81 0.399 0.0696 1.46 1.6019 0.9614 1390944 IFLab1_002309 COc1ccc(CCNC(=O)CSc2c[nH]c3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I22 compound treatment 0.326 -0.00444 -0.17 0.377 0.0476 1.0 0.5813 0.5746 1616799 IFLab1_002310 CCOc1ccc(cc1)C(=O)Nc2c3CS(=O)Cc3nn2c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I23 mock treatment 0.332 0.00156 0.06 0.334 0.00463 0.1 0.1119 0.9759 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 I24 positive control 0.086 -0.244 -9.61 0.083 -0.246 -5.16 -10.4415 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J01 compound treatment 0.352 0.0216 0.85 0.347 0.0176 0.37 0.8603 0.9305 2066694 IFLab1_002311 C=CCSc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J02 compound treatment 0.371 0.0406 1.59 0.366 0.0366 0.77 1.6697 0.9436 1702777 IFLab1_002312 NC(=O)CSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J03 compound treatment 0.333 0.00256 0.1 0.383 0.0536 1.12 0.8647 0.7675 2066695 IFLab1_002313 FC(F)(F)c1cccc(CSc2nc3n(ncc3c(=O)[nH]2)c4ccccc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J04 compound treatment 0.324 -0.00644 -0.25 0.37 0.0406 0.85 0.4222 0.4759 1237051 IFLab1_002314 CCOC(=O)C(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J05 compound treatment 0.343 0.0126 0.49 0.403 0.0736 1.54 1.4387 0.8892 1157350 IFLab1_002315 Cc1[nH]c2ccccc2c1SCC(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J06 compound treatment 0.338 0.00756 0.3 0.389 0.0596 1.25 1.0925 0.8518 2066696 IFLab1_002316 Fc1cccc(F)c1C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J07 compound treatment 0.339 0.00856 0.34 0.42 0.0906 1.9 1.579 0.8198 1105705 IFLab1_002317 Cc1cccc(Nc2ncnc3[nH]cnc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J08 compound treatment 0.339 0.00856 0.34 0.47 0.141 2.94 2.3189 0.7829 2066697 IFLab1_002318 CC(Oc1ccccc1)C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J09 compound treatment 0.337 0.00656 0.26 0.449 0.12 2.5 1.9526 0.7759 1554706 IFLab1_002319 C(Nc1ncnc2[nH]cnc12)C3CCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J10 compound treatment 0.344 0.0136 0.53 0.441 0.112 2.34 2.0288 0.8467 2066698 IFLab1_002320 CC(=O)NCCSc1c(C)[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J11 compound treatment 0.347 0.0166 0.65 0.447 0.118 2.46 2.201 0.8644 1287684 IFLab1_002321 CCC(CO)Nc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J12 compound treatment 0.338 0.00756 0.3 0.467 0.138 2.88 2.2467 0.776 2066699 IFLab1_002322 CC(=O)NCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J13 compound treatment 0.346 0.0156 0.61 0.471 0.142 2.96 2.5283 0.8355 1206546 IFLab1_002323 C1Cc2ccccc2N1c3ncnc4[nH]cnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J14 compound treatment 0.349 0.0186 0.73 0.476 0.147 3.07 2.6857 0.8515 2066700 IFLab1_002324 CCn1c(CNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J15 compound treatment 0.349 0.0186 0.73 0.483 0.154 3.21 2.7893 0.8461 1015839 IFLab1_002325 Fc1cccc(CSc2ncnc3[nH]cnc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J16 compound treatment 0.346 0.0156 0.61 0.48 0.151 3.15 2.6615 0.8289 2066701 IFLab1_002326 CCCCn1c(CNC(=O)CC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J17 compound treatment 0.347 0.0166 0.65 0.476 0.147 3.07 2.6301 0.8385 2066702 IFLab1_002327 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J18 compound treatment 0.346 0.0156 0.61 0.455 0.126 2.63 2.2916 0.849 2066703 IFLab1_002328 COCC(=O)NCc1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J19 compound treatment 0.348 0.0176 0.69 0.45 0.121 2.52 2.2732 0.8686 2066704 IFLab1_002329 O=c1c2SCCc2nc(SCc3ccccc3)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J20 compound treatment 0.35 0.0196 0.77 0.419 0.0896 1.88 1.8701 0.9225 2066705 IFLab1_002330 CC(C)Cn1c(CNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J21 compound treatment 0.346 0.0156 0.61 0.412 0.0826 1.73 1.6553 0.9025 2066706 IFLab1_002331 CCSc1nc2CCSc2c(=O)n1c3ccccc3OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J22 compound treatment 0.342 0.0116 0.45 0.399 0.0696 1.46 1.3517 0.8856 2066707 IFLab1_002332 CC(=C)Cn1c(CNC(=O)c2ccc(F)cc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J23 mock treatment 0.33 -4.37E-4 -0.02 0.332 0.00263 0.05 0.0267 0.4635 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 J24 positive control 0.088 -0.242 -9.53 0.086 -0.243 -5.09 -10.3415 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K01 compound treatment 0.367 0.0366 1.44 0.361 0.0316 0.66 1.4845 0.938 1379846 IFLab1_002333 NS(=O)(=O)c1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K02 compound treatment 0.337 0.00656 0.26 0.336 0.00663 0.14 0.2805 0.9576 2066708 IFLab1_002334 CC(C)(C)c1cnnn1c2ccc(NC(=O)c3ccc(Br)o3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K03 compound treatment 0.38 0.0496 1.95 0.405 0.0756 1.58 2.497 0.9947 1415594 IFLab1_002335 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4CCCCc4c3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K04 compound treatment 0.347 0.0166 0.65 0.369 0.0396 0.83 1.0468 0.9928 2066709 IFLab1_002336 CC(=O)Nc1ccc(cc1)n2nncc2c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K05 compound treatment 0.346 0.0156 0.61 0.372 0.0426 0.89 1.0634 0.9831 1736282 IFLab1_002337 CC(C)(C)n1nc2CS(=O)(=O)Cc2c1NC(=O)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K06 compound treatment 0.369 0.0386 1.52 0.417 0.0876 1.83 2.3687 0.9955 1606600 IFLab1_002338 O=C(CSc1cn(CCNC(=O)c2ccccc2)c3ccccc13)Nc4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K07 compound treatment 0.369 0.0386 1.52 0.417 0.0876 1.83 2.3687 0.9955 1259324 IFLab1_002339 Cc1cccc(c1C)n2nc3CS(=O)(=O)Cc3c2NC(=O)c4c(F)cccc4Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K08 compound treatment 0.378 0.0476 1.87 0.426 0.0966 2.02 2.7521 0.9992 2066710 IFLab1_002340 CCC1CCCCN1C(=O)COc2cccc3C(=O)N(C)CCc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K09 compound treatment 0.361 0.0306 1.2 0.423 0.0936 1.96 2.2351 0.9725 2066711 IFLab1_002341 CCC1CCCCN1C(=O)CSC2=NN3CCCC(=O)N=C3S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K10 compound treatment 0.345 0.0146 0.57 0.439 0.11 2.29 2.027 0.8573 2066712 IFLab1_002342 CCCOc1cccc2C(=O)N(CC)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K11 compound treatment 0.349 0.0186 0.73 0.476 0.147 3.07 2.6857 0.8515 2066713 IFLab1_002343 O=C(CSC1=NN2CCCC(=O)N=C2S1)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K12 compound treatment 0.33 -4.37E-4 -0.02 0.473 0.144 3.01 2.1131 0.703 2066714 IFLab1_002344 COC(=O)c1ccc(COc2cccc3C(=O)N(Cc4ccccc4)CCc23)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K13 compound treatment 0.33 -4.37E-4 -0.02 0.462 0.133 2.78 1.9503 0.7027 1287039 IFLab1_002345 Cc1ccc(NC(=O)CSc2cn(C)c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K14 compound treatment 0.361 0.0306 1.2 0.422 0.0926 1.94 2.2203 0.9736 2066715 IFLab1_002346 O=C(COc1cccc2C(=O)N(Cc3ccccc3)CCc12)NCc4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K15 compound treatment 0.358 0.0276 1.08 0.483 0.154 3.21 3.0395 0.8959 1337054 IFLab1_002347 CCn1cc(SCC(=O)NC2CCCCC2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K16 compound treatment 0.355 0.0246 0.97 0.489 0.16 3.34 3.0449 0.8757 1485238 IFLab1_002348 Cc1sc(NC(=O)CSCC(=O)N2CCCCC2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K17 compound treatment 0.345 0.0146 0.57 0.422 0.0926 1.94 1.7754 0.8785 1720561 IFLab1_002349 CCCn1cc(SCC(=O)Nc2nccs2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K18 compound treatment 0.35 0.0196 0.77 0.455 0.126 2.63 2.4028 0.8772 1691725 IFLab1_002350 Fc1ccc(cc1)C2N(CC(=O)Nc3ccc(F)cc23)C(=O)C4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K19 compound treatment 0.346 0.0156 0.61 0.383 0.0536 1.12 1.2262 0.9593 1714284 IFLab1_002351 O=C(CSc1c[nH]c2ccccc12)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K20 compound treatment 0.349 0.0186 0.73 0.409 0.0796 1.67 1.6943 0.9314 2066716 IFLab1_002352 CC(C)CC(=O)Nc1c2CS(=O)Cc2nn1c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K21 compound treatment 0.343 0.0126 0.49 0.409 0.0796 1.67 1.5275 0.8789 1552804 IFLab1_002353 COc1ccc(NC(=O)CSc2c[nH]c3ccccc23)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K22 compound treatment 0.331 5.63E-4 0.02 0.383 0.0536 1.12 0.8091 0.7209 1685998 IFLab1_002354 CC(C)(C)c1ccc(cc1)C(=O)Nc2c3CS(=O)Cc3nn2c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K23 mock treatment 0.337 0.00656 0.26 0.32 -0.00937 -0.2 0.0437 0.1349 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 K24 positive control 0.087 -0.243 -9.57 0.087 -0.242 -5.07 -10.3545 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L01 compound treatment 0.358 0.0276 1.08 0.359 0.0296 0.62 1.2047 0.9649 2066717 IFLab1_002355 CSc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L02 compound treatment 0.345 0.0146 0.57 0.358 0.0286 0.6 0.8284 0.9997 1500101 IFLab1_002356 CSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L03 compound treatment 0.352 0.0216 0.85 0.366 0.0366 0.77 1.1414 0.9987 2066718 IFLab1_002357 Cc1cccc(CSc2nc3n(ncc3c(=O)[nH]2)c4ccc(Cl)cc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L04 compound treatment 0.344 0.0136 0.53 0.365 0.0356 0.75 0.9042 0.9865 1324500 IFLab1_002358 COC(=O)C(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L05 compound treatment 0.348 0.0176 0.69 0.372 0.0426 0.89 1.119 0.992 1682223 IFLab1_002359 Cc1[nH]c2ccccc2c1SCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L06 compound treatment 0.341 0.0106 0.42 0.395 0.0656 1.37 1.2647 0.8815 2066719 IFLab1_002360 COc1ccccc1C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L07 compound treatment 0.353 0.0226 0.89 0.407 0.0776 1.62 1.7759 0.9595 1015182 IFLab1_002361 COc1ccc(Nc2ncnc3[nH]cnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L08 compound treatment 0.36 0.0296 1.16 0.409 0.0796 1.67 2.0001 0.9845 2066720 IFLab1_002362 Cc1cccc(c1)C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L09 compound treatment 0.334 0.00356 0.14 0.431 0.102 2.13 1.6028 0.7521 1540141 IFLab1_002363 CC(Nc1ncnc2[nH]cnc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L10 compound treatment 0.373 0.0426 1.67 0.447 0.118 2.46 2.9238 0.9823 2066721 IFLab1_002364 Cc1[nH]c2ccccc2c1SCCNC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L11 compound treatment 0.341 0.0106 0.42 0.452 0.123 2.57 2.1082 0.811 1666417 IFLab1_002365 CCCN(CCC)c1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L12 compound treatment 0.365 0.0346 1.36 0.446 0.117 2.44 2.6866 0.9618 2066722 IFLab1_002366 CCC(=O)NCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L13 compound treatment 0.352 0.0216 0.85 0.432 0.103 2.15 2.118 0.9174 1569766 IFLab1_002367 OC1CCN(CC1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L14 compound treatment 0.351 0.0206 0.81 0.398 0.0686 1.44 1.5871 0.9631 2066723 IFLab1_002368 CCn1c(CNC(=O)COC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L15 compound treatment 0.345 0.0146 0.57 0.436 0.107 2.23 1.9826 0.8607 1070173 IFLab1_002369 COc1ccccc1CNc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L16 compound treatment 0.335 0.00456 0.18 0.451 0.122 2.55 1.9265 0.7551 2066724 IFLab1_002370 CCCCn1c(CNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L17 compound treatment 0.358 0.0276 1.08 0.411 0.0816 1.71 1.9741 0.9759 2066725 IFLab1_002371 CCC1CCCCN1C(=O)CSc2nc3CCSc3c(=O)n2c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L18 compound treatment 0.345 0.0146 0.57 0.435 0.106 2.21 1.9678 0.8618 2066726 IFLab1_002372 CCCC(=O)NCc1nc2ccccc2n1Cc3cc(C)ccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L19 compound treatment 0.347 0.0166 0.65 0.417 0.0876 1.83 1.7571 0.903 2066727 IFLab1_002373 COC(=O)c1ccc(CSc2nc3CCSc3c(=O)n2c4ccccc4)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L20 compound treatment 0.355 0.0246 0.97 0.396 0.0666 1.39 1.6687 0.9839 2066728 IFLab1_002374 CC(C)Cn1c(CNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L21 compound treatment 0.331 5.63E-4 0.02 0.382 0.0526 1.1 0.7943 0.7212 2066729 IFLab1_002375 COc1ccccc1n2c(SCc3ccc(F)cc3)nc4CCSc4c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L22 compound treatment 0.345 0.0146 0.57 0.366 0.0366 0.77 0.9468 0.9897 2066730 IFLab1_002376 CC(=C)Cn1c(CNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L23 mock treatment 0.333 0.00256 0.1 0.325 -0.00437 -0.09 0.0065 0.0478 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 L24 positive control 0.089 -0.241 -9.49 0.086 -0.243 -5.09 -10.3137 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M01 compound treatment 0.342 0.0116 0.45 0.357 0.0276 0.58 0.7302 0.9929 1137296 IFLab1_002377 O=C(NCc1ccccc1)c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M02 compound treatment 0.376 0.0456 1.79 0.363 0.0336 0.7 1.7643 0.9167 2066731 IFLab1_002378 CC(=O)Nc1ccc(cc1)n2nncc2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M03 compound treatment 0.359 0.0286 1.12 0.35 0.0206 0.43 1.0993 0.9137 1609713 IFLab1_002379 O=C(Nc1nc(cs1)c2ccncc2)C3COc4ccccc4O3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M04 compound treatment 0.327 -0.00344 -0.14 0.346 0.0166 0.35 0.1504 0.4031 2066732 IFLab1_002380 CSc1ncnc2n(cc(c3ccccc3)c12)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M05 compound treatment 0.341 0.0106 0.42 0.348 0.0186 0.39 0.5693 0.9995 1373988 IFLab1_002381 CC(=O)Nc1c2CS(=O)(=O)Cc2nn1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M06 compound treatment 0.344 0.0136 0.53 0.379 0.0496 1.04 1.1114 0.952 1591870 IFLab1_002382 C=CCn1c(=O)c2ccccc2c3ccccc3c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M07 compound treatment 0.356 0.0256 1.01 0.416 0.0866 1.81 1.9925 0.9613 1542921 IFLab1_002383 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)CCC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M08 compound treatment 0.374 0.0436 1.71 0.391 0.0616 1.29 2.123 0.9902 2066733 IFLab1_002384 CN1CCc2c(OCc3ccccc3Cl)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M09 compound treatment 0.35 0.0196 0.77 0.408 0.0786 1.65 1.7073 0.94 2066734 IFLab1_002385 O=C(CSC1=NN2CCCC(=O)N=C2S1)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M10 compound treatment 0.351 0.0206 0.81 0.387 0.0576 1.21 1.4244 0.9811 2066735 IFLab1_002386 CCN1CCc2c(OC(C)C)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M11 compound treatment 0.36 0.0296 1.16 0.414 0.0846 1.77 2.0741 0.9791 1736080 IFLab1_002387 O=C(CSc1cn(Cc2ccccc2)c3ccccc13)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M12 compound treatment 0.357 0.0266 1.04 0.431 0.102 2.13 2.2422 0.9464 2066736 IFLab1_002388 COc1cccc2C(=O)N(Cc3ccccc3)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M13 compound treatment 0.342 0.0116 0.45 0.437 0.108 2.25 1.914 0.833 1211414 IFLab1_002389 CCOC(=O)c1ccc(NC(=O)CSc2cn(C)c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M14 compound treatment 0.357 0.0266 1.04 0.411 0.0816 1.71 1.9463 0.9721 2066737 IFLab1_002390 Cc1ccccc1CN2CCc3c(OCC(=O)N4CCOCC4)cccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M15 compound treatment 0.342 0.0116 0.45 0.443 0.114 2.38 2.0028 0.8273 1364028 IFLab1_002391 CCn1cc(SCC(=O)N2CCc3ccccc23)c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M16 compound treatment 0.352 0.0216 0.85 0.442 0.113 2.36 2.266 0.9047 1545038 IFLab1_002392 CC(C)CC(=O)N1CC(=O)Nc2ccc(C)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M17 compound treatment 0.362 0.0316 1.24 0.454 0.125 2.61 2.7216 0.9423 1675792 IFLab1_002393 CCCn1cc(SCC(=O)Nc2nnc(SCC)s2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M18 compound treatment 0.356 0.0256 1.01 0.413 0.0836 1.75 1.9481 0.9653 1149106 IFLab1_002394 CC(Oc1ccccc1)C(=O)N2CC(=O)Nc3ccc(F)cc3C2c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M19 compound treatment 0.352 0.0216 0.85 0.389 0.0596 1.25 1.4818 0.9823 1575533 IFLab1_002395 O=C(CSc1c[nH]c2ccccc12)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M20 compound treatment 0.355 0.0246 0.97 0.362 0.0326 0.68 1.1656 0.9856 1739369 IFLab1_002396 Cc1cccc(c1C)n2nc3CS(=O)Cc3c2NC(=O)c4ccc(Br)o4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M21 compound treatment 0.344 0.0136 0.53 0.365 0.0356 0.75 0.9042 0.9865 1124986 IFLab1_002397 O=C(CSc1c[nH]c2ccccc12)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M22 compound treatment 0.338 0.00756 0.3 0.359 0.0296 0.62 0.6486 0.9434 2066738 IFLab1_002398 FC(F)(F)c1cccc(c1)C(=O)Nc2c3CS(=O)Cc3nn2c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M23 mock treatment 0.298 -0.0324 -1.28 0.312 -0.0174 -0.36 -1.1589 -0.8739 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 M24 positive control 0.09 -0.24 -9.45 0.087 -0.242 -5.07 -10.2711 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N01 compound treatment 0.352 0.0216 0.85 0.354 0.0246 0.52 0.9639 0.9715 2066739 IFLab1_002399 CCSc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N02 compound treatment 0.339 0.00856 0.34 0.334 0.00463 0.1 0.3065 0.8749 1246183 IFLab1_002400 CCSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N03 compound treatment 0.335 0.00456 0.18 0.351 0.0216 0.45 0.4468 0.9179 2066740 IFLab1_002401 Cc1ccc(cc1)n2ncc3c(=O)[nH]c(SCc4ccccc4F)nc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N04 compound treatment 0.36 0.0296 1.16 0.363 0.0336 0.7 1.3194 0.9711 2066741 IFLab1_002402 O=C(Cc1ccccc1)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N05 compound treatment 0.367 0.0366 1.44 0.381 0.0516 1.08 1.7804 0.9901 1703926 IFLab1_002403 O=C(CSc1c([nH]c2ccccc12)c3ccccc3)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N06 compound treatment 0.362 0.0316 1.24 0.382 0.0526 1.1 1.6562 0.9982 2066742 IFLab1_002404 COc1cccc(c1)C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N07 compound treatment 0.352 0.0216 0.85 0.377 0.0476 1.0 1.3042 0.9968 1680511 IFLab1_002405 CCOc1ccc(Nc2ncnc3[nH]cnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N08 compound treatment 0.369 0.0386 1.52 0.404 0.0746 1.56 2.1763 0.9999 2066743 IFLab1_002406 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N09 compound treatment 0.356 0.0256 1.01 0.397 0.0676 1.42 1.7113 0.9859 1606233 IFLab1_002407 COc1ccc(CNc2ncnc3[nH]cnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N10 compound treatment 0.346 0.0156 0.61 0.404 0.0746 1.56 1.5369 0.9163 2066744 IFLab1_002408 CC(C)C(=O)NCCSc1c(C)[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N11 compound treatment 0.366 0.0356 1.4 0.405 0.0756 1.58 2.1077 0.9981 1628336 IFLab1_002409 C(N(Cc1ccccc1)c2ncnc3[nH]cnc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N12 compound treatment 0.358 0.0276 1.08 0.408 0.0786 1.65 1.9297 0.9795 2066745 IFLab1_002410 CCCC(=O)NCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N13 compound treatment 0.355 0.0246 0.97 0.42 0.0906 1.9 2.0239 0.951 1343384 IFLab1_002411 Cc1ccc(C)c(c1)N2CCN(CC2)c3ncnc4[nH]cnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N14 compound treatment 0.351 0.0206 0.81 0.414 0.0846 1.77 1.8239 0.9369 2066746 IFLab1_002412 CCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N15 compound treatment 0.339 0.00856 0.34 0.411 0.0816 1.71 1.4459 0.8305 2066747 IFLab1_002413 C(CNc1ncnc2[nH]cnc12)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N16 compound treatment 0.345 0.0146 0.57 0.404 0.0746 1.56 1.5091 0.9073 2066748 IFLab1_002414 CCCCn1c(CNC(=O)COC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N17 compound treatment 0.337 0.00656 0.26 0.399 0.0696 1.46 1.2127 0.8196 2066749 IFLab1_002415 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N18 compound treatment 0.351 0.0206 0.81 0.38 0.0506 1.06 1.3208 0.9911 2066750 IFLab1_002416 CC(=O)NCc1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N19 compound treatment 0.343 0.0126 0.49 0.363 0.0336 0.7 0.8468 0.985 2066751 IFLab1_002417 CCOC(=O)CSc1nc2CCSc2c(=O)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N20 compound treatment 0.351 0.0206 0.81 0.361 0.0316 0.66 1.0396 0.9951 2066752 IFLab1_002418 COc1ccc(cc1OC)C(=O)NCc2nc3ccccc3n2CC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N21 compound treatment 0.354 0.0236 0.93 0.357 0.0276 0.58 1.0639 0.9742 2066753 IFLab1_002419 COc1ccc(cc1)n2c(SCC(=O)NCCc3ccccc3)nc4CCSc4c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N22 compound treatment 0.345 0.0146 0.57 0.349 0.0196 0.41 0.6953 0.9867 2066754 IFLab1_002420 CCCC(=O)NCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N23 mock treatment 0.334 0.00356 0.14 0.34 0.0106 0.22 0.2563 0.9752 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 N24 positive control 0.09 -0.24 -9.45 0.089 -0.24 -5.03 -10.2415 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O01 compound treatment 0.35 0.0196 0.77 0.364 0.0346 0.72 1.0562 0.9996 2066755 IFLab1_002421 O=C(N1CCCCC1)c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O02 compound treatment 0.371 0.0406 1.59 0.361 0.0316 0.66 1.5957 0.9241 2066756 IFLab1_002422 O=C(COc1ccccc1)Nc2ccc(cc2)n3nncc3c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O03 compound treatment 0.326 -0.00444 -0.17 0.332 0.00263 0.05 -0.0845 -0.4621 1560385 IFLab1_002423 COC(=O)c1sc(cc1NC(=O)C2COc3ccccc3O2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O04 compound treatment 0.341 0.0106 0.42 0.335 0.00563 0.12 0.3769 0.8731 1284076 IFLab1_002424 COc1ccc(cc1)n2cc(c3ccccc3)c4c(SC)ncnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O05 compound treatment 0.34 0.00956 0.38 0.352 0.0226 0.47 0.6006 0.9935 1188956 IFLab1_002425 CC(C)C(=O)Nc1c2CS(=O)(=O)Cc2nn1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O06 compound treatment 0.345 0.0146 0.57 0.329 -3.75E-4 -0.01 0.3993 0.6974 1159535 IFLab1_002426 COCCn1c(=O)c2ccccc2c3ccccc3c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O07 compound treatment 0.366 0.0356 1.4 0.369 0.0396 0.83 1.575 0.9689 1651482 IFLab1_002427 COc1cccc(C(=O)Nc2c3CSCc3nn2c4ccc(F)cc4)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O08 compound treatment 0.368 0.0376 1.48 0.367 0.0376 0.79 1.6011 0.9566 2066757 IFLab1_002428 CN1CCc2c(OCC(=O)N3CCCCCC3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O09 compound treatment 0.369 0.0386 1.52 0.366 0.0366 0.77 1.6141 0.9501 2066758 IFLab1_002429 O=C(CSC1=NN2CCCC(=O)N=C2S1)N3CCC(Cc4ccccc4)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O10 compound treatment 0.346 0.0156 0.61 0.334 0.00463 0.1 0.5011 0.8089 2066759 IFLab1_002430 CCN1CCc2c(OCc3ccc(C)cc3)cccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O11 compound treatment 0.35 0.0196 0.77 0.35 0.0206 0.43 0.8491 0.9627 1669221 IFLab1_002431 O=C(CSc1cn(Cc2ccccc2)c3ccccc13)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O12 compound treatment 0.336 0.00556 0.22 0.333 0.00363 0.08 0.2083 0.8998 2066760 IFLab1_002432 CCCOc1cccc2C(=O)N(Cc3ccccc3)CCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O13 compound treatment 0.363 0.0326 1.28 0.363 0.0336 0.7 1.4029 0.9603 1539780 IFLab1_002433 Cn1cc(SCC(=O)Nc2ccc3OCCOc3c2)c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O14 compound treatment 0.349 0.0186 0.73 0.346 0.0166 0.35 0.7621 0.9426 2066761 IFLab1_002434 Clc1ccc(COc2cccc3C(=O)N(Cc4cccnc4)CCc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O15 compound treatment 0.357 0.0266 1.04 0.347 0.0176 0.37 0.9993 0.9022 1338499 IFLab1_002435 CCn1cc(SCC(=O)Nc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O16 compound treatment 0.358 0.0276 1.08 0.356 0.0266 0.56 1.1603 0.9522 1234655 IFLab1_002436 Cc1ccc2NC(=O)CN(C(c3ccc(F)cc3)c2c1)C(=O)c4ccc(Br)o4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O17 compound treatment 0.35 0.0196 0.77 0.349 0.0196 0.41 0.8343 0.9568 1606138 IFLab1_002437 CCCn1cc(SCC(=O)Nc2cc(C)on2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O18 compound treatment 0.352 0.0216 0.85 0.348 0.0186 0.39 0.8751 0.9378 1356340 IFLab1_002438 CCCCC(=O)N1CC(=O)Nc2ccc(F)cc2C1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O19 compound treatment 0.347 0.0166 0.65 0.351 0.0216 0.45 0.7805 0.9842 1446040 IFLab1_002439 O=C(CSc1c[nH]c2ccccc12)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O20 compound treatment 0.352 0.0216 0.85 0.347 0.0176 0.37 0.8603 0.9305 1165282 IFLab1_002440 CC(C)C(=O)Nc1c2CS(=O)Cc2nn1C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O21 compound treatment 0.384 0.0536 2.11 0.371 0.0416 0.87 2.1051 0.9237 1658135 IFLab1_002441 CCSc1nnc(NC(=O)CSc2c[nH]c3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O22 compound treatment 0.334 0.00356 0.14 0.331 0.00163 0.03 0.1231 0.854 1674962 IFLab1_002442 O=C(Nc1c2CS(=O)Cc2nn1c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O23 mock treatment 0.34 0.00956 0.38 0.327 -0.00237 -0.05 0.2307 0.6083 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 O24 positive control 0.093 -0.237 -9.34 0.092 -0.237 -4.97 -10.1137 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P01 compound treatment 0.354 0.0236 0.93 0.348 0.0186 0.39 0.9307 0.926 2066762 IFLab1_002443 CCCSc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P02 compound treatment 0.346 0.0156 0.61 0.349 0.0196 0.41 0.7231 0.9812 1652304 IFLab1_002444 CCCSc1nc2c3ccccc3[nH]c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P03 compound treatment 0.353 0.0226 0.89 0.354 0.0246 0.52 0.9917 0.9666 2066763 IFLab1_002445 Cc1ccc(cc1)n2ncc3c(=O)[nH]c(SCC(=O)c4ccccc4)nc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P04 compound treatment 0.389 0.0586 2.3 0.379 0.0496 1.04 2.3625 0.9353 2066764 IFLab1_002446 COc1ccc(CC(=O)NCCSc2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P05 compound treatment 0.389 0.0586 2.3 0.398 0.0686 1.44 2.6436 0.9742 1227813 IFLab1_002447 CCOC(=O)N1CCN(CC1)C(=O)CSc2c([nH]c3ccccc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P06 compound treatment 0.397 0.0666 2.62 0.388 0.0586 1.23 2.7181 0.9404 2066765 IFLab1_002448 CCOc1ccc(cc1)C(=O)NCCSc2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P07 compound treatment 0.377 0.0466 1.83 0.391 0.0616 1.29 2.2064 0.9853 1579426 IFLab1_002449 CCCNc1ncnc2[nH]cnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P08 compound treatment 0.421 0.0906 3.56 0.452 0.123 2.57 4.3323 0.9871 2066766 IFLab1_002450 O=C(NCCSc1c[nH]c2ccccc12)c3ccc(cc3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P09 compound treatment 0.393 0.0626 2.46 0.38 0.0506 1.06 2.4885 0.9291 1427094 IFLab1_002451 C(CC1=CCCCC1)Nc2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P10 compound treatment 0.394 0.0636 2.5 0.398 0.0686 1.44 2.7826 0.9654 2066767 IFLab1_002452 CCC(=O)NCCSc1c(C)[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P11 compound treatment 0.388 0.0576 2.26 0.52 0.191 3.99 4.4211 0.964 1378306 IFLab1_002453 CN(C1CCCCC1)c2ncnc3[nH]cnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P12 compound treatment 0.382 0.0516 2.03 0.374 0.0446 0.93 2.0939 0.9381 2066768 IFLab1_002454 Cn1c(CNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P13 compound treatment 0.387 0.0566 2.22 0.391 0.0616 1.29 2.4844 0.9664 1589607 IFLab1_002455 CC1Cc2ccccc2N1c3ncnc4[nH]cnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P14 compound treatment 0.387 0.0566 2.22 0.375 0.0456 0.95 2.2477 0.9287 2066769 IFLab1_002456 CCn1c(CNC(=O)c2ccc(OC)c(OC)c2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P15 compound treatment 0.38 0.0496 1.95 0.41 0.0806 1.69 2.571 0.9974 2066770 IFLab1_002457 CCN(CCCNc1ncnc2[nH]cnc12)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P16 compound treatment 0.369 0.0386 1.52 0.369 0.0396 0.83 1.6585 0.9597 2066771 IFLab1_002458 CCCCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P17 compound treatment 0.374 0.0436 1.71 0.365 0.0356 0.75 1.7383 0.9306 2066772 IFLab1_002459 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P18 compound treatment 0.363 0.0326 1.28 0.366 0.0366 0.77 1.4472 0.9699 2066773 IFLab1_002460 CCC(=O)NCc1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P19 compound treatment 0.365 0.0346 1.36 0.366 0.0366 0.77 1.5029 0.9633 2066774 IFLab1_002461 CCC(Sc1nc2CCSc2c(=O)n1c3ccccc3)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P20 compound treatment 0.361 0.0306 1.2 0.369 0.0396 0.83 1.436 0.9836 1986829 IFLab1_002462 CC(=O)NCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P21 compound treatment 0.361 0.0306 1.2 0.345 0.0156 0.33 1.0809 0.868 2066775 IFLab1_002463 CCOc1ccc(cc1)n2c(SC(C)CC)nc3CCSc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P22 compound treatment 0.357 0.0266 1.04 0.345 0.0156 0.33 0.9697 0.8861 2066776 IFLab1_002464 CC(C)(C)C(=O)NCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P23 mock treatment 0.344 0.0136 0.53 0.35 0.0206 0.43 0.6823 0.9945 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1418 P24 positive control 0.097 -0.233 -9.18 0.094 -0.235 -4.93 -9.9729 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A01 compound treatment 0.35 0.0238 0.93 0.347 0.0218 0.46 0.9831 0.9458 2066777 IFLab1_002465 COCC(=O)NCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A02 compound treatment 0.326 -2.5E-4 -0.01 0.327 0.00181 0.04 0.0199 0.5071 2066778 IFLab1_002466 CCCn1c(CCCNC(=O)CC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A03 compound treatment 0.327 7.5E-4 0.03 0.349 0.0238 0.5 0.3732 0.7476 2066779 IFLab1_002467 CCn1c(nc2ccccc12)C(C)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A04 compound treatment 0.339 0.0127 0.5 0.322 -0.00319 -0.07 0.3073 0.6077 2066780 IFLab1_002468 CCCCn1c(CCCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A05 compound treatment 0.324 -0.00225 -0.09 0.325 -1.88E-4 0.0 -0.0653 -0.7377 2066781 IFLab1_002469 CCCCn1c(nc2ccccc12)C(C)NC(=O)CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A06 compound treatment 0.326 -2.5E-4 -0.01 0.317 -0.00819 -0.17 -0.1281 -0.7464 2066782 IFLab1_002470 C=CCn1c(CCCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A07 compound treatment 0.33 0.00375 0.15 0.324 -0.00119 -0.02 0.0867 0.5798 2066783 IFLab1_002471 CC(NC(=O)C)c1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A08 compound treatment 0.328 0.00175 0.07 0.35 0.0248 0.52 0.4158 0.7939 2066784 IFLab1_002472 CC(=O)NC(c1nc2ccccc2[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A09 compound treatment 0.345 0.0187 0.74 0.328 0.00281 0.06 0.5629 0.7611 2066785 IFLab1_002473 COCC(=O)NC(C)c1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A10 compound treatment 0.321 -0.00525 -0.21 0.319 -0.00619 -0.13 -0.2375 -0.9748 2066786 IFLab1_002474 O=C(CSc1oc(nc1S(=O)(=O)c2ccccc2)c3cccs3)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A11 compound treatment 0.331 0.00475 0.19 0.345 0.0198 0.41 0.4252 0.9351 2066787 IFLab1_002475 Cn1c(CCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A12 compound treatment 0.376 0.0498 1.96 0.343 0.0178 0.37 1.6467 0.827 2066788 IFLab1_002476 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A13 compound treatment 0.327 7.5E-4 0.03 0.326 8.12E-4 0.02 0.0329 0.9658 2066789 IFLab1_002477 CCC(=O)NCCc1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A14 compound treatment 0.326 -2.5E-4 -0.01 0.353 0.0278 0.58 0.4046 0.6951 2066790 IFLab1_002478 COc1ccc(cc1)c2nc3ccccn3c2NC(=O)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A15 compound treatment 0.343 0.0168 0.66 0.322 -0.00319 -0.07 0.4185 0.6323 2066791 IFLab1_002479 Cc1ccccc1Cn2c(CCNC(=O)C(C)(C)C)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A16 compound treatment 0.328 0.00175 0.07 0.325 -1.88E-4 0.0 0.0459 0.6657 2066792 IFLab1_002480 Cc1ccn2c(NC(=O)C3CC3)c(nc2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A17 compound treatment 0.329 0.00275 0.11 0.328 0.00281 0.06 0.1181 0.9591 2066793 IFLab1_002481 CC(C)(C)C(=O)NCCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A18 compound treatment 0.328 0.00175 0.07 0.34 0.0148 0.31 0.2678 0.8435 2066794 IFLab1_002482 Clc1ccc(CS(=O)(=O)c2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A19 compound treatment 0.345 0.0187 0.74 0.325 -1.88E-4 0.0 0.5185 0.7033 2066795 IFLab1_002483 COCC(=O)NCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A20 compound treatment 0.327 7.5E-4 0.03 0.313 -0.0122 -0.26 -0.1595 -0.6212 2066796 IFLab1_002484 CCCn1cc(c2ccccc12)S(=O)(=O)CC(=O)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A21 compound treatment 0.319 -0.00725 -0.29 0.321 -0.00419 -0.09 -0.2635 -0.8837 2066797 IFLab1_002485 CCC(=O)NCCCc1nc2ccccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A22 compound treatment 0.346 0.0198 0.78 0.352 0.0268 0.56 0.9458 0.9873 2066798 IFLab1_002486 Clc1ccc(Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)Nc4nccs4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A23 mock treatment 0.319 -0.00725 -0.29 0.318 -0.00719 -0.15 -0.3079 -0.9554 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 A24 positive control 0.079 -0.247 -9.72 0.08 -0.245 -5.13 -10.5021 -0.9554 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B01 compound treatment 0.339 0.0127 0.5 0.35 0.0248 0.52 0.7216 0.9998 2066799 IFLab1_002487 Cc1ccc(cc1)c2nnc(SCC(=O)NC3CCCCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B02 compound treatment 0.323 -0.00325 -0.13 0.327 0.00181 0.04 -0.0635 -0.4767 2066800 IFLab1_002488 COc1ccc(CNCc2cn3c(nnc3s2)c4ccc(Br)cc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B03 compound treatment 0.324 -0.00225 -0.09 0.323 -0.00219 -0.05 -0.0949 -0.953 2066801 IFLab1_002489 O=C(CSc1nnc(Cc2ccccc2)o1)N3CCN(CC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B04 compound treatment 0.329 0.00275 0.11 0.33 0.00481 0.1 0.1477 0.9994 2066802 IFLab1_002490 CCCC(=O)NCCc1cc2cc(C)c(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B05 compound treatment 0.329 0.00275 0.11 0.318 -0.00719 -0.15 -0.0299 -0.1614 2066803 IFLab1_002491 O=C(CSc1ncnc2c3ccccc3oc12)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B06 compound treatment 0.321 -0.00525 -0.21 0.323 -0.00219 -0.05 -0.1783 -0.8434 2066804 IFLab1_002492 Cc1ccc2cc(CCNC(=O)C3CC3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B07 compound treatment 0.342 0.0158 0.62 0.332 0.00681 0.14 0.5387 0.8477 1987303 IFLab1_002493 O=C(CSc1ncnc2c3ccccc3oc12)NCCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B08 compound treatment 0.34 0.0138 0.54 0.337 0.0118 0.25 0.5571 0.9371 2066805 IFLab1_002494 CC(C)C(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B09 compound treatment 0.337 0.0107 0.42 0.331 0.00581 0.12 0.3849 0.8751 2066806 IFLab1_002495 COC(=O)C(C)Sc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B10 compound treatment 0.336 0.00975 0.38 0.336 0.0108 0.23 0.4311 0.9684 2066807 IFLab1_002496 COc1ccc2cc(CCNC(=O)/C=C\c3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B11 compound treatment 0.328 0.00175 0.07 0.344 0.0188 0.39 0.327 0.8183 2066808 IFLab1_002497 CCSc1nnc(NC(=O)CSc2nccn2c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B12 compound treatment 0.335 0.00875 0.34 0.327 0.00181 0.04 0.2701 0.7803 2066809 IFLab1_002498 COc1ccc2cc(CCNC(=O)c3ccco3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B13 compound treatment 0.332 0.00575 0.23 0.336 0.0108 0.23 0.3199 1.0 2066810 IFLab1_002499 O=C(CSc1nccn1c2ccccc2)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B14 compound treatment 0.349 0.0227 0.89 0.346 0.0208 0.44 0.9405 0.9453 2066811 IFLab1_002500 COc1ccc(cc1OC)C(=O)NCCc2cc3c(C)ccc(C)c3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B15 compound treatment 0.327 7.5E-4 0.03 0.327 0.00181 0.04 0.0477 0.9923 2066812 IFLab1_002501 Cc1cc(C)cc(c1)n2ccnc2SCC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B16 compound treatment 0.342 0.0158 0.62 0.341 0.0158 0.33 0.6719 0.9569 2066813 IFLab1_002502 Cc1ccc2cc(CCNC(=O)c3cc4ccccc4oc3=O)c(=O)[nH]c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B17 compound treatment 0.347 0.0208 0.82 0.348 0.0228 0.48 0.9145 0.9674 2066814 IFLab1_002503 CCOc1ccc(cc1)n2ccnc2SCC(=O)Nc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B18 compound treatment 0.34 0.0138 0.54 0.341 0.0158 0.33 0.6163 0.9722 2066815 IFLab1_002504 O=C(Cc1ccccc1)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B19 compound treatment 0.333 0.00675 0.27 0.322 -0.00319 -0.07 0.1405 0.5134 2066816 IFLab1_002505 Cc1ccc(NC(=O)CSc2nccn2c3ccc(Cl)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B20 compound treatment 0.335 0.00875 0.34 0.341 0.0158 0.33 0.4772 0.9998 2066817 IFLab1_002506 O=C(NCCn1ccc2ccccc12)/C=C/c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B21 compound treatment 0.341 0.0147 0.58 0.342 0.0168 0.35 0.6589 0.9713 2066818 IFLab1_002507 CC(=O)Nc1ccc2n(C)c(=NC(=O)c3ccc(Br)s3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B22 compound treatment 0.336 0.00975 0.38 0.333 0.00781 0.16 0.3867 0.9278 2066819 IFLab1_002508 O=C(NCCn1ccc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B23 mock treatment 0.327 7.5E-4 0.03 0.326 8.12E-4 0.02 0.0329 0.9658 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 B24 positive control 0.079 -0.247 -9.72 0.079 -0.246 -5.15 -10.5169 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C01 compound treatment 0.347 0.0208 0.82 0.342 0.0168 0.35 0.8257 0.9293 2066820 IFLab1_002509 O=C(Cc1ccccc1)NCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C02 compound treatment 0.319 -0.00725 -0.29 0.328 0.00281 0.06 -0.1599 -0.5495 2066821 IFLab1_002510 CCCn1c(CCCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C03 compound treatment 0.333 0.00675 0.27 0.302 -0.0232 -0.49 -0.1554 -0.2811 2066822 IFLab1_002511 CCC(=O)NC(C)c1nc2ccccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C04 compound treatment 0.338 0.0118 0.46 0.341 0.0158 0.33 0.5607 0.9866 2066823 IFLab1_002512 CCCCn1c(CCCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C05 compound treatment 0.341 0.0147 0.58 0.333 0.00781 0.16 0.5257 0.8724 2066824 IFLab1_002513 CCCCn1c(nc2ccccc12)C(C)NC(=O)c3ccc(OC)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C06 compound treatment 0.341 0.0147 0.58 0.329 0.00381 0.08 0.4665 0.7969 2066825 IFLab1_002514 CCC(=O)NCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C07 compound treatment 0.328 0.00175 0.07 0.329 0.00381 0.08 0.1051 0.9973 2066826 IFLab1_002515 CC(NC(=O)C(C)(C)C)c1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C08 compound treatment 0.347 0.0208 0.82 0.341 0.0158 0.33 0.8109 0.921 2066827 IFLab1_002516 Cn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C09 compound treatment 0.339 0.0127 0.5 0.341 0.0158 0.33 0.5885 0.9797 1586768 IFLab1_002517 CC(NC(=O)c1ccccc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C10 compound treatment 0.343 0.0168 0.66 0.352 0.0268 0.56 0.8624 0.9968 2066828 IFLab1_002518 CSc1oc(nc1S(=O)(=O)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C11 compound treatment 0.33 0.00375 0.15 0.327 0.00181 0.04 0.1311 0.861 2066829 IFLab1_002519 COc1ccc(cc1OC)C(=O)NCCc2nc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C12 compound treatment 0.34 0.0138 0.54 0.337 0.0118 0.25 0.5571 0.9371 2066830 IFLab1_002520 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C13 compound treatment 0.333 0.00675 0.27 0.338 0.0128 0.27 0.3773 1.0 2066831 IFLab1_002521 CC(C)n1c(CCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C14 compound treatment 0.337 0.0107 0.42 0.34 0.0148 0.31 0.5181 0.9884 2066832 IFLab1_002522 CCCCC(=O)Nc1c(nc2ccccn12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C15 compound treatment 0.337 0.0107 0.42 0.338 0.0128 0.27 0.4885 0.9759 2066833 IFLab1_002523 COCC(=O)NCCc1nc2ccccc2n1Cc3c(F)cccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C16 compound treatment 0.338 0.0118 0.46 0.326 8.12E-4 0.02 0.3387 0.7326 2066834 IFLab1_002524 O=C(CS(=O)(=O)c1c[nH]c2ccccc12)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C17 compound treatment 0.339 0.0127 0.5 0.337 0.0118 0.25 0.5293 0.9469 2066835 IFLab1_002525 C=CCn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C18 compound treatment 0.325 -0.00125 -0.05 0.327 0.00181 0.04 -0.0079 -0.1278 2066836 IFLab1_002526 FC(F)(F)c1ccc(CS(=O)(=O)c2c[nH]c3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C19 compound treatment 0.34 0.0138 0.54 0.336 0.0108 0.23 0.5423 0.9253 2066837 IFLab1_002527 CCC(=O)NCCCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C20 compound treatment 0.336 0.00975 0.38 0.332 0.00681 0.14 0.3719 0.9092 2066838 IFLab1_002528 CCCn1cc(c2ccccc12)S(=O)(=O)CC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C21 compound treatment 0.336 0.00975 0.38 0.337 0.0118 0.25 0.4459 0.9775 2066839 IFLab1_002529 CCn1c(CCCNC(=O)c2cccc(C)c2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C22 compound treatment 0.336 0.00975 0.38 0.336 0.0108 0.23 0.4311 0.9684 2066840 IFLab1_002530 Clc1ccccc1Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C23 mock treatment 0.323 -0.00325 -0.13 0.323 -0.00219 -0.05 -0.1227 -0.9042 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 C24 positive control 0.08 -0.246 -9.68 0.079 -0.246 -5.15 -10.4891 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D01 compound treatment 0.348 0.0217 0.86 0.352 0.0268 0.56 1.0014 0.9791 2066841 IFLab1_002531 COc1ccccc1c2nnc(SCC(=O)NC3CCCCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D02 compound treatment 0.324 -0.00225 -0.09 0.339 0.0138 0.29 0.1418 0.4692 2066842 IFLab1_002532 C(NCc1ccccc1)c2cn3c(nnc3s2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D03 compound treatment 0.329 0.00275 0.11 0.334 0.00881 0.18 0.2069 0.9676 2066843 IFLab1_002533 O=C(CSc1nnc(Cc2ccccc2)o1)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D04 compound treatment 0.33 0.00375 0.15 0.335 0.00981 0.21 0.2495 0.9868 2066844 IFLab1_002534 Cc1cc2cc(CCNC(=O)CC3CCCCC3)c(=O)[nH]c2cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D05 compound treatment 0.345 0.0187 0.74 0.348 0.0228 0.48 0.8588 0.9779 2066845 IFLab1_002535 O=C(CSc1ncnc2c3ccccc3oc12)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D06 compound treatment 0.342 0.0158 0.62 0.344 0.0188 0.39 0.7163 0.9761 2066846 IFLab1_002536 Cc1ccc2cc(CCNC(=O)Cc3cccs3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D07 compound treatment 0.351 0.0248 0.97 0.342 0.0168 0.35 0.9369 0.9054 2066847 IFLab1_002537 COc1cccc(NC(=O)CSc2ncnc3c4ccccc4oc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D08 compound treatment 0.345 0.0187 0.74 0.342 0.0168 0.35 0.7701 0.9427 2066848 IFLab1_002538 Cc1ccc2cc(CCNC(=O)c3ccco3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D09 compound treatment 0.344 0.0177 0.7 0.344 0.0188 0.39 0.7719 0.9633 2066849 IFLab1_002539 O=C(CSc1ncnc2c3ccccc3oc12)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D10 compound treatment 0.339 0.0127 0.5 0.348 0.0228 0.48 0.692 0.9997 2066850 IFLab1_002540 COc1ccc2cc(CCNC(=O)C3CC3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D11 compound treatment 0.345 0.0187 0.74 0.343 0.0178 0.37 0.7849 0.9501 2066851 IFLab1_002541 O=C(CSc1nccn1c2ccccc2)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D12 compound treatment 0.349 0.0227 0.89 0.341 0.0158 0.33 0.8665 0.9085 2066852 IFLab1_002542 CCC(C(=O)NCCc1cc2ccc(OC)cc2[nH]c1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D13 compound treatment 0.348 0.0217 0.86 0.337 0.0118 0.25 0.7795 0.8757 2066853 IFLab1_002543 Cc1cc(NC(=O)CSc2nccn2c3ccccc3)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D14 compound treatment 0.341 0.0147 0.58 0.348 0.0228 0.48 0.7476 0.9953 2066854 IFLab1_002544 Cc1ccc(C)c2[nH]c(=O)c(CCNC(=O)c3ccc4OCOc4c3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D15 compound treatment 0.329 0.00275 0.11 0.339 0.0138 0.29 0.2808 0.91 2066855 IFLab1_002545 COc1cccc(c1)n2ccnc2SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D16 compound treatment 0.344 0.0177 0.7 0.334 0.00881 0.18 0.6239 0.8643 2066856 IFLab1_002546 CCS(=O)(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D17 compound treatment 0.32 -0.00625 -0.25 0.341 0.0158 0.33 0.0602 0.1461 2066857 IFLab1_002547 CCOc1ccc(cc1)n2ccnc2SCC(=O)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D18 compound treatment 0.341 0.0147 0.58 0.338 0.0128 0.27 0.5997 0.9386 2066858 IFLab1_002548 COc1cc(cc(OC)c1OC)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D19 compound treatment 0.339 0.0127 0.5 0.333 0.00781 0.16 0.4701 0.8915 2066859 IFLab1_002549 Clc1ccc(cc1)n2ccnc2SCC(=O)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D20 compound treatment 0.345 0.0187 0.74 0.353 0.0278 0.58 0.9328 0.9932 2066860 IFLab1_002550 O=C(NCCn1ccc2ccccc12)C3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D21 compound treatment 0.338 0.0118 0.46 0.342 0.0168 0.35 0.5754 0.991 2066861 IFLab1_002551 CC(=O)Nc1ccc2n(C)c(=NC(=O)c3ccc4ncsc4c3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D22 compound treatment 0.34 0.0138 0.54 0.336 0.0108 0.23 0.5423 0.9253 2066862 IFLab1_002552 CC(C)C(=O)NCCn1ccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D23 mock treatment 0.321 -0.00525 -0.21 0.326 8.12E-4 0.02 -0.1339 -0.6467 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 D24 positive control 0.082 -0.244 -9.6 0.08 -0.245 -5.13 -10.4187 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E01 compound treatment 0.327 7.5E-4 0.03 0.337 0.0118 0.25 0.1956 0.7859 2066863 IFLab1_002553 O=C(NCc1nc2ccccc2[nH]1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E02 compound treatment 0.319 -0.00725 -0.29 0.325 -1.88E-4 0.0 -0.2043 -0.7168 2066864 IFLab1_002554 CCCn1c(CCCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E03 compound treatment 0.321 -0.00525 -0.21 0.326 8.12E-4 0.02 -0.1339 -0.6467 2066865 IFLab1_002555 CCn1c(nc2ccccc12)C(C)NC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E04 compound treatment 0.327 7.5E-4 0.03 0.319 -0.00619 -0.13 -0.0707 -0.5324 2066866 IFLab1_002556 CC(=O)NCCCc1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E05 compound treatment 0.33 0.00375 0.15 0.327 0.00181 0.04 0.1311 0.861 2066867 IFLab1_002557 CC(NC(=O)C)c1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E06 compound treatment 0.334 0.00775 0.3 0.33 0.00481 0.1 0.2867 0.8933 1986706 IFLab1_002558 CC(C)(C)C(=O)NCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E07 compound treatment 0.336 0.00975 0.38 0.337 0.0118 0.25 0.4459 0.9775 2066868 IFLab1_002559 CC(NC(=O)c1ccccc1)c2nc3ccccc3n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E08 compound treatment 0.342 0.0158 0.62 0.342 0.0168 0.35 0.6867 0.9641 2066869 IFLab1_002560 Cn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E09 compound treatment 0.349 0.0227 0.89 0.349 0.0238 0.5 0.9849 0.9618 2066870 IFLab1_002561 COc1ccc(cc1OC)C(=O)NC(C)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E10 compound treatment 0.337 0.0107 0.42 0.334 0.00881 0.18 0.4293 0.9309 2066871 IFLab1_002562 CCSc1oc(nc1S(=O)(=O)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E11 compound treatment 0.347 0.0208 0.82 0.341 0.0158 0.33 0.8109 0.921 2066872 IFLab1_002563 CCn1c(CCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E12 compound treatment 0.348 0.0217 0.86 0.344 0.0188 0.39 0.8831 0.938 2066873 IFLab1_002564 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)Cc3ccc(OCC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E13 compound treatment 0.342 0.0158 0.62 0.337 0.0118 0.25 0.6127 0.9189 2066874 IFLab1_002565 CC(C)n1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E14 compound treatment 0.34 0.0138 0.54 0.336 0.0108 0.23 0.5423 0.9253 2066875 IFLab1_002566 O=C(COc1ccccc1)Nc2c(nc3ccccn23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E15 compound treatment 0.331 0.00475 0.19 0.328 0.00281 0.06 0.1737 0.8869 2066876 IFLab1_002567 COCC(=O)NCCc1nc2ccccc2n1Cc3cc(C)ccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E16 compound treatment 0.338 0.0118 0.46 0.338 0.0128 0.27 0.5163 0.9665 2066877 IFLab1_002568 O=C(CS(=O)(=O)c1c[nH]c2ccccc12)N3CCN(CC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E17 compound treatment 0.318 -0.00825 -0.32 0.334 0.00881 0.18 -0.099 -0.2652 2066878 IFLab1_002569 C=CCn1c(CCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E18 compound treatment 0.338 0.0118 0.46 0.339 0.0138 0.29 0.5311 0.9745 2066879 IFLab1_002570 Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)N3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E19 compound treatment 0.333 0.00675 0.27 0.338 0.0128 0.27 0.3773 1.0 2066880 IFLab1_002571 Cn1c(CCCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E20 compound treatment 0.352 0.0257 1.01 0.349 0.0238 0.5 1.0683 0.9467 2066881 IFLab1_002572 CCCn1cc(c2ccccc12)S(=O)(=O)CC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E21 compound treatment 0.339 0.0127 0.5 0.34 0.0148 0.31 0.5737 0.9733 2066882 IFLab1_002573 CCn1c(CCCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E22 compound treatment 0.342 0.0158 0.62 0.33 0.00481 0.1 0.5091 0.8114 2066883 IFLab1_002574 CCC1CCCCN1C(=O)CSc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E23 mock treatment 0.321 -0.00525 -0.21 0.321 -0.00419 -0.09 -0.2079 -0.9272 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 E24 positive control 0.082 -0.244 -9.6 0.082 -0.243 -5.09 -10.3891 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F01 compound treatment 0.328 0.00175 0.07 0.337 0.0118 0.25 0.2234 0.8708 2066884 IFLab1_002575 O=C(CSc1nnc(o1)c2cccs2)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F02 compound treatment 0.33 0.00375 0.15 0.322 -0.00319 -0.07 0.0571 0.3528 2066885 IFLab1_002576 CC(C)C(=O)Oc1c(c(C)nn1C(C)(C)C)S(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F03 compound treatment 0.316 -0.0103 -0.4 0.317 -0.00819 -0.17 -0.4061 -0.9274 2066886 IFLab1_002577 O=C(CSc1nnc(Cc2ccccc2)o1)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F04 compound treatment 0.331 0.00475 0.19 0.331 0.00581 0.12 0.2181 0.9784 2066887 IFLab1_002578 COc1ccc(CC(=O)NCCc2cc3cc(C)c(C)cc3[nH]c2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F05 compound treatment 0.344 0.0177 0.7 0.336 0.0108 0.23 0.6535 0.8907 2066888 IFLab1_002579 COc1ccc(NC(=O)CSc2ncnc3c4ccccc4oc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F06 compound treatment 0.335 0.00875 0.34 0.33 0.00481 0.1 0.3145 0.8773 2066889 IFLab1_002580 Cc1ccc2cc(CCNC(=O)/C=C\c3ccc4OCOc4c3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F07 compound treatment 0.336 0.00975 0.38 0.336 0.0108 0.23 0.4311 0.9684 2066890 IFLab1_002581 CSc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F08 compound treatment 0.347 0.0208 0.82 0.331 0.00581 0.12 0.6629 0.8036 2066891 IFLab1_002582 COc1ccc(C(=O)NCCc2cc3ccc(C)cc3[nH]c2=O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F09 compound treatment 0.342 0.0158 0.62 0.344 0.0188 0.39 0.7163 0.9761 2066892 IFLab1_002583 NC(=O)CSC1=NN2CCCC(=O)N=C2S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F10 compound treatment 0.349 0.0227 0.89 0.341 0.0158 0.33 0.8665 0.9085 2066893 IFLab1_002584 COc1ccc2cc(CCNC(=O)C3CCCC3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F11 compound treatment 0.347 0.0208 0.82 0.33 0.00481 0.1 0.6481 0.7884 2066894 IFLab1_002585 CCOC(=O)c1ccc(NC(=O)CSc2nccn2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F12 compound treatment 0.334 0.00775 0.3 0.337 0.0118 0.25 0.3903 0.9946 2066895 IFLab1_002586 COc1ccc2cc(CCNC(=O)C(C)Oc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F13 compound treatment 0.354 0.0278 1.09 0.333 0.00781 0.16 0.8871 0.8041 2066896 IFLab1_002587 CCc1ccc(NC(=O)CSc2nccn2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F14 compound treatment 0.351 0.0248 0.97 0.335 0.00981 0.21 0.8333 0.8379 2066897 IFLab1_002588 CC(Oc1ccccc1)C(=O)NCCc2cc3c(C)ccc(C)c3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F15 compound treatment 0.345 0.0187 0.74 0.345 0.0198 0.41 0.8145 0.9629 2066898 IFLab1_002589 COc1cccc(c1)n2ccnc2SCC(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F16 compound treatment 0.35 0.0238 0.93 0.35 0.0248 0.52 1.0275 0.9616 2066899 IFLab1_002590 Cc1ccc2cc(CCNS(=O)(=O)c3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F17 compound treatment 0.351 0.0248 0.97 0.352 0.0268 0.56 1.0848 0.9658 2066900 IFLab1_002591 COc1ccc(NC(=O)CSc2nccn2c3ccc(F)cc3)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F18 compound treatment 0.344 0.0177 0.7 0.334 0.00881 0.18 0.6239 0.8643 2066901 IFLab1_002592 Clc1ccc(OCC(=O)NCCn2ccc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F19 compound treatment 0.365 0.0388 1.52 0.349 0.0238 0.5 1.4297 0.8919 2066902 IFLab1_002593 COc1ccc(OC)c(NC(=O)CSc2nccn2c3ccc(Cl)cc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F20 compound treatment 0.338 0.0118 0.46 0.341 0.0158 0.33 0.5607 0.9866 2066903 IFLab1_002594 Fc1cccc(F)c1C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F21 compound treatment 0.34 0.0138 0.54 0.342 0.0168 0.35 0.6311 0.9783 2066904 IFLab1_002595 Brc1cccc(c1)c2nnc3sc(CNCc4ccco4)cn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F22 compound treatment 0.338 0.0118 0.46 0.339 0.0138 0.29 0.5311 0.9745 2066905 IFLab1_002596 COc1ccc(C(=O)NCCn2ccc3ccccc23)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F23 mock treatment 0.323 -0.00325 -0.13 0.321 -0.00419 -0.09 -0.1523 -0.9831 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 F24 positive control 0.083 -0.243 -9.56 0.082 -0.243 -5.09 -10.3613 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G01 compound treatment 0.335 0.00875 0.34 0.336 0.0108 0.23 0.4033 0.9793 2066906 IFLab1_002597 CC(NC(=O)C)c1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G02 compound treatment 0.316 -0.0103 -0.4 0.314 -0.0112 -0.23 -0.4505 -0.9666 2066907 IFLab1_002598 CC(C)n1c(CCCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G03 compound treatment 0.327 7.5E-4 0.03 0.316 -0.00919 -0.19 -0.1151 -0.5917 2066908 IFLab1_002599 CCn1c(nc2ccccc12)C(C)NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G04 compound treatment 0.343 0.0168 0.66 0.321 -0.00419 -0.09 0.4037 0.6077 2066909 IFLab1_002600 CCC(=O)NCCCc1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G05 compound treatment 0.316 -0.0103 -0.4 0.32 -0.00519 -0.11 -0.3617 -0.8667 2066910 IFLab1_002601 CCC(=O)NC(C)c1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G06 compound treatment 0.324 -0.00225 -0.09 0.318 -0.00719 -0.15 -0.1689 -0.968 2066911 IFLab1_002602 O=C(NCCCc1nc2ccccc2[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G07 compound treatment 0.34 0.0138 0.54 0.333 0.00781 0.16 0.4979 0.8815 2066912 IFLab1_002603 CC(NC(=O)Cc1ccccc1)c2nc3ccccc3n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G08 compound treatment 0.327 7.5E-4 0.03 0.341 0.0158 0.33 0.2548 0.7671 2066913 IFLab1_002604 CCn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G09 compound treatment 0.326 -2.5E-4 -0.01 0.324 -0.00119 -0.02 -0.0245 -0.9176 2066914 IFLab1_002605 CCC(=O)NCCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G10 compound treatment 0.352 0.0257 1.01 0.353 0.0278 0.58 1.1274 0.9654 2066915 IFLab1_002606 CSc1oc(nc1S(=O)(=O)c2ccc(F)cc2)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G11 compound treatment 0.34 0.0138 0.54 0.334 0.00881 0.18 0.5127 0.8975 2066916 IFLab1_002607 CCC(=O)NCCc1nc2ccccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G12 compound treatment 0.364 0.0377 1.48 0.36 0.0348 0.73 1.5646 0.9463 2066917 IFLab1_002608 Fc1ccc(cc1)c2nc3ccccn3c2NC(=O)COc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G13 compound treatment 0.342 0.0158 0.62 0.331 0.00581 0.12 0.5239 0.8301 2066918 IFLab1_002609 CCCCn1c(CCNC(=O)CC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G14 compound treatment 0.343 0.0168 0.66 0.344 0.0188 0.39 0.7441 0.9697 2066919 IFLab1_002610 O=C(Nc1c(nc2ccccn12)c3cccs3)/C=C\c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G15 compound treatment 0.33 0.00375 0.15 0.324 -0.00119 -0.02 0.0867 0.5798 2066920 IFLab1_002611 CC(C)(C)C(=O)NCCc1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G16 compound treatment 0.337 0.0107 0.42 0.334 0.00881 0.18 0.4293 0.9309 2066921 IFLab1_002612 O=C(CS(=O)(=O)c1c[nH]c2ccccc12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G17 compound treatment 0.341 0.0147 0.58 0.332 0.00681 0.14 0.5109 0.8555 2066922 IFLab1_002613 COc1ccc(cc1OC)C(=O)NCCc2nc3ccccc3n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G18 compound treatment 0.336 0.00975 0.38 0.335 0.00981 0.21 0.4163 0.9572 2066923 IFLab1_002614 Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G19 compound treatment 0.347 0.0208 0.82 0.334 0.00881 0.18 0.7073 0.8456 2066924 IFLab1_002615 Cn1c(CCCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G20 compound treatment 0.369 0.0428 1.68 0.362 0.0368 0.77 1.7333 0.9374 2066925 IFLab1_002616 COc1ccc(NC(=O)CS(=O)(=O)c2cn(Cc3cccc(F)c3)c4ccccc24)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G21 compound treatment 0.338 0.0118 0.46 0.332 0.00681 0.14 0.4275 0.8842 2066926 IFLab1_002617 CCn1c(CCCNC(=O)c2ccc(Cl)cc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G22 compound treatment 0.334 0.00775 0.3 0.327 0.00181 0.04 0.2423 0.789 2066927 IFLab1_002618 O=C(CSc1nnc(o1)c2ccccc2)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G23 mock treatment 0.321 -0.00525 -0.21 0.321 -0.00419 -0.09 -0.2079 -0.9272 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 G24 positive control 0.083 -0.243 -9.56 0.082 -0.243 -5.09 -10.3613 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H01 compound treatment 0.342 0.0158 0.62 0.337 0.0118 0.25 0.6127 0.9189 2066928 IFLab1_002619 O=C(CSc1nnc(o1)c2ccco2)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H02 compound treatment 0.32 -0.00625 -0.25 0.323 -0.00219 -0.05 -0.2061 -0.8246 2066929 IFLab1_002620 Cc1nn(c(OC(=O)C2CC2)c1S(=O)(=O)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H03 compound treatment 0.323 -0.00325 -0.13 0.322 -0.00319 -0.07 -0.1375 -0.9541 2066930 IFLab1_002621 CC1CC(C)CN(C1)C(=O)CSc2nnc(Cc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H04 compound treatment 0.327 7.5E-4 0.03 0.323 -0.00219 -0.05 -0.0115 -0.2115 2066931 IFLab1_002622 CCCC(=O)NCCc1cc2c(OC)ccc(OC)c2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H05 compound treatment 0.352 0.0257 1.01 0.348 0.0228 0.48 1.0535 0.9411 2066932 IFLab1_002623 Cc1cccc(NC(=O)CSc2ncnc3c4ccccc4oc23)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H06 compound treatment 0.335 0.00875 0.34 0.329 0.00381 0.08 0.2997 0.8486 2066933 IFLab1_002624 Cc1ccc2cc(CCNC(=O)C3CCCC3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H07 compound treatment 0.344 0.0177 0.7 0.357 0.0318 0.67 0.9642 0.9997 2066934 IFLab1_002625 CCSc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H08 compound treatment 0.344 0.0177 0.7 0.342 0.0168 0.35 0.7423 0.9497 2066935 IFLab1_002626 Cc1ccc2cc(CCNC(=O)CCC3CCCC3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H09 compound treatment 0.35 0.0238 0.93 0.345 0.0198 0.41 0.9535 0.9332 2066936 IFLab1_002627 O=C(CSC1=NN2CCCC(=O)N=C2S1)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H10 compound treatment 0.353 0.0267 1.05 0.358 0.0328 0.69 1.2292 0.9786 2066937 IFLab1_002628 COc1ccc2cc(CCNC(=O)c3cccc(c3)C(F)(F)F)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H11 compound treatment 0.344 0.0177 0.7 0.341 0.0158 0.33 0.7275 0.9419 2066938 IFLab1_002629 Cc1cccc(NC(=O)CSc2nccn2c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H12 compound treatment 0.351 0.0248 0.97 0.346 0.0208 0.44 0.9961 0.9343 2066939 IFLab1_002630 COc1ccc2cc(CCNC(=O)CCCc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H13 compound treatment 0.354 0.0278 1.09 0.335 0.00981 0.21 0.9167 0.8257 2066940 IFLab1_002631 O=C(CSc1nccn1c2ccccc2)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H14 compound treatment 0.349 0.0227 0.89 0.335 0.00981 0.21 0.7777 0.8474 2066941 IFLab1_002632 COc1cc(OC)cc(c1)C(=O)NCCc2cc3ccc(C)c(C)c3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H15 compound treatment 0.34 0.0138 0.54 0.339 0.0138 0.29 0.5867 0.957 2066942 IFLab1_002633 COc1cccc(c1)n2ccnc2SCC(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H16 compound treatment 0.341 0.0147 0.58 0.332 0.00681 0.14 0.5109 0.8555 2066943 IFLab1_002634 COc1ccc2cc(CCNS(=O)(=O)C)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H17 compound treatment 0.351 0.0248 0.97 0.337 0.0118 0.25 0.8629 0.8594 2066944 IFLab1_002635 Fc1ccc(cc1)n2ccnc2SCC(=O)Nc3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H18 compound treatment 0.332 0.00575 0.23 0.337 0.0118 0.25 0.3347 0.999 2066945 IFLab1_002636 CCOc1ccccc1C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H19 compound treatment 0.33 0.00375 0.15 0.337 0.0118 0.25 0.279 0.9695 2066946 IFLab1_002637 Clc1ccc(cc1)n2ccnc2SCC(=O)NC3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H20 compound treatment 0.342 0.0158 0.62 0.339 0.0138 0.29 0.6423 0.9398 2066947 IFLab1_002638 Clc1ccc(C(=O)NCCn2ccc3ccccc23)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H21 compound treatment 0.337 0.0107 0.42 0.338 0.0128 0.27 0.4885 0.9759 2066948 IFLab1_002639 CC1CCCCN1Cc2cn3c(nnc3s2)c4ccc(Br)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H22 compound treatment 0.337 0.0107 0.42 0.333 0.00781 0.16 0.4145 0.9146 2066949 IFLab1_002640 O=C(NCCn1ccc2ccccc12)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H23 mock treatment 0.322 -0.00425 -0.17 0.328 0.00281 0.06 -0.0765 -0.432 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 H24 positive control 0.085 -0.241 -9.49 0.083 -0.242 -5.07 -10.2909 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I01 compound treatment 0.349 0.0227 0.89 0.346 0.0208 0.44 0.9405 0.9453 2066950 IFLab1_002641 CCC(=O)NC(C)c1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I02 compound treatment 0.336 0.00975 0.38 0.341 0.0158 0.33 0.505 0.9973 2066951 IFLab1_002642 CCC(=O)NCCCc1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I03 compound treatment 0.339 0.0127 0.5 0.343 0.0178 0.37 0.618 0.9894 2066952 IFLab1_002643 CCCn1c(nc2ccccc12)C(C)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I04 compound treatment 0.33 0.00375 0.15 0.324 -0.00119 -0.02 0.0867 0.5798 2066953 IFLab1_002644 CC(C)Cn1c(CCCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I05 compound treatment 0.342 0.0158 0.62 0.347 0.0218 0.46 0.7606 0.9887 2066954 IFLab1_002645 CC(NC(=O)C(C)(C)C)c1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I06 compound treatment 0.335 0.00875 0.34 0.341 0.0158 0.33 0.4772 0.9998 2066955 IFLab1_002646 Cc1cccc(c1)C(=O)NCCCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I07 compound treatment 0.329 0.00275 0.11 0.353 0.0278 0.58 0.488 0.8244 2066956 IFLab1_002647 COCC(=O)NC(C)c1nc2ccccc2n1CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I08 compound treatment 0.343 0.0168 0.66 0.352 0.0268 0.56 0.8624 0.9968 2066957 IFLab1_002648 CCn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)COC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I09 compound treatment 0.348 0.0217 0.86 0.344 0.0188 0.39 0.8831 0.938 2066958 IFLab1_002649 CCCC(=O)NCCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I10 compound treatment 0.347 0.0208 0.82 0.348 0.0228 0.48 0.9145 0.9674 2066959 IFLab1_002650 CCCCC(=O)Nc1c([nH]c2ccccc12)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I11 compound treatment 0.347 0.0208 0.82 0.342 0.0168 0.35 0.8257 0.9293 2066960 IFLab1_002651 CCn1c(CCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I12 compound treatment 0.349 0.0227 0.89 0.351 0.0258 0.54 1.0144 0.9708 2066961 IFLab1_002652 CC(C)CC(=O)Nc1c(nc2ccccn12)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I13 compound treatment 0.342 0.0158 0.62 0.345 0.0198 0.41 0.731 0.981 2066962 IFLab1_002653 CCCCn1c(CCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I14 compound treatment 0.369 0.0428 1.68 0.352 0.0268 0.56 1.5853 0.8946 2066963 IFLab1_002654 Fc1cccc(F)c1C(=O)Nc2c(nc3ccccn23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I15 compound treatment 0.348 0.0217 0.86 0.326 8.12E-4 0.02 0.6167 0.721 2066964 IFLab1_002655 CC(C)Cn1c(CCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I16 compound treatment 0.341 0.0147 0.58 0.339 0.0138 0.29 0.6145 0.9483 2066965 IFLab1_002656 Cc1cccc(NC(=O)CS(=O)(=O)c2c[nH]c3ccccc23)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I17 compound treatment 0.337 0.0107 0.42 0.342 0.0168 0.35 0.5476 0.9958 2066966 IFLab1_002657 CCCC(=O)NCCc1nc2ccccc2n1CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I18 compound treatment 0.345 0.0187 0.74 0.338 0.0128 0.27 0.7109 0.9062 2066967 IFLab1_002658 Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I19 compound treatment 0.337 0.0107 0.42 0.339 0.0138 0.29 0.5033 0.9828 2066968 IFLab1_002659 Cn1c(CCCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I20 compound treatment 0.335 0.00875 0.34 0.342 0.0168 0.35 0.492 0.9999 2066969 IFLab1_002660 Fc1ccc(Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)N4CCCCC4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I21 compound treatment 0.345 0.0187 0.74 0.339 0.0138 0.29 0.7257 0.9164 2066970 IFLab1_002661 CCn1c(CCCNC(=O)c2ccc(OC)c(OC)c2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I22 compound treatment 0.336 0.00975 0.38 0.335 0.00981 0.21 0.4163 0.9572 2066971 IFLab1_002662 O=C(CSc1nnc(o1)c2ccccc2)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I23 mock treatment 0.331 0.00475 0.19 0.33 0.00481 0.1 0.2033 0.958 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 I24 positive control 0.086 -0.24 -9.45 0.083 -0.242 -5.07 -10.2631 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J01 compound treatment 0.338 0.0118 0.46 0.324 -0.00119 -0.02 0.3091 0.6681 2066972 IFLab1_002663 CC1CCCN(C1)C(=O)CSc2nnc(o2)c3ccc(Cl)s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J02 compound treatment 0.33 0.00375 0.15 0.321 -0.00419 -0.09 0.0423 0.2466 2066973 IFLab1_002664 CC(=O)Nc1nnc(o1)c2ccc3CCCCc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J03 compound treatment 0.326 -2.5E-4 -0.01 0.327 0.00181 0.04 0.0199 0.5071 2066974 IFLab1_002665 Clc1ccc(OCc2nnc(SCC(=O)N3CCc4ccccc34)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J04 compound treatment 0.33 0.00375 0.15 0.326 8.12E-4 0.02 0.1163 0.7835 2066975 IFLab1_002666 COc1ccc(OC)c2[nH]c(=O)c(CCNC(=O)CC3CCCCC3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J05 compound treatment 0.336 0.00975 0.38 0.34 0.0148 0.31 0.4903 0.9944 2066976 IFLab1_002667 O=C(CSc1ncnc2c3ccccc3oc12)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J06 compound treatment 0.338 0.0118 0.46 0.324 -0.00119 -0.02 0.3091 0.6681 2066977 IFLab1_002668 COc1ccc(Cl)cc1C(=O)NCCc2cc3ccc(C)cc3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J07 compound treatment 0.327 7.5E-4 0.03 0.337 0.0118 0.25 0.1956 0.7859 2066978 IFLab1_002669 CCCSc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J08 compound treatment 0.331 0.00475 0.19 0.332 0.00681 0.14 0.2329 0.9911 2066979 IFLab1_002670 CCC(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J09 compound treatment 0.352 0.0257 1.01 0.346 0.0208 0.44 1.0239 0.929 2066980 IFLab1_002671 O=C(CSC1=NN2CCCC(=O)N=C2S1)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J10 compound treatment 0.329 0.00275 0.11 0.342 0.0168 0.35 0.3252 0.8836 2066981 IFLab1_002672 COc1ccc2cc(CCNC(=O)CC(C)C)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J11 compound treatment 0.337 0.0107 0.42 0.342 0.0168 0.35 0.5476 0.9958 2066982 IFLab1_002673 CCOc1ccc(NC(=O)CSc2nccn2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J12 compound treatment 0.334 0.00775 0.3 0.337 0.0118 0.25 0.3903 0.9946 2066983 IFLab1_002674 COc1cccc(C(=O)NCCc2cc3c(C)ccc(C)c3[nH]c2=O)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J13 compound treatment 0.35 0.0238 0.93 0.332 0.00681 0.14 0.7611 0.8057 2066984 IFLab1_002675 COc1cccc(NC(=O)CSc2nccn2c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J14 compound treatment 0.352 0.0257 1.01 0.346 0.0208 0.44 1.0239 0.929 2066985 IFLab1_002676 CCOc1ccccc1C(=O)NCCc2cc3ccc(C)c(C)c3[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J15 compound treatment 0.338 0.0118 0.46 0.337 0.0118 0.25 0.5015 0.9571 2066986 IFLab1_002677 COc1ccc(cc1)n2ccnc2SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J16 compound treatment 0.347 0.0208 0.82 0.347 0.0218 0.46 0.8997 0.9623 2066987 IFLab1_002678 CCS(=O)(=O)NCCc1cc2ccc(OC)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J17 compound treatment 0.346 0.0198 0.78 0.323 -0.00219 -0.05 0.5167 0.6643 2066988 IFLab1_002679 COc1ccc(OC)c(NC(=O)CSc2nccn2c3cccc(Cl)c3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J18 compound treatment 0.343 0.0168 0.66 0.342 0.0168 0.35 0.7145 0.9569 2066989 IFLab1_002680 O=C(NCCn1ccc2ccccc12)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J19 compound treatment 0.352 0.0257 1.01 0.341 0.0158 0.33 0.9499 0.8918 1410330 IFLab1_002681 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3c(F)cc(F)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J20 compound treatment 0.346 0.0198 0.78 0.344 0.0188 0.39 0.8275 0.9504 2066990 IFLab1_002682 O=C(NCCn1ccc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J21 compound treatment 0.341 0.0147 0.58 0.346 0.0208 0.44 0.718 0.99 2066991 IFLab1_002683 Brc1ccc(cc1)c2nnc3sc(CN4CCCCCC4)cn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J22 compound treatment 0.337 0.0107 0.42 0.342 0.0168 0.35 0.5476 0.9958 2066992 IFLab1_002684 CC(Oc1ccccc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J23 mock treatment 0.322 -0.00425 -0.17 0.326 8.12E-4 0.02 -0.1061 -0.6319 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 J24 positive control 0.087 -0.239 -9.41 0.084 -0.241 -5.05 -10.2205 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K01 compound treatment 0.344 0.0177 0.7 0.338 0.0128 0.27 0.6831 0.9137 2066993 IFLab1_002685 CC(NC(=O)C(C)(C)C)c1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K02 compound treatment 0.327 7.5E-4 0.03 0.321 -0.00419 -0.09 -0.0411 -0.4447 2066994 IFLab1_002686 CC(C)n1c(CCCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K03 compound treatment 0.32 -0.00625 -0.25 0.326 8.12E-4 0.02 -0.1617 -0.6566 2066995 IFLab1_002687 CCCn1c(nc2ccccc12)C(C)NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K04 compound treatment 0.322 -0.00425 -0.17 0.334 0.00881 0.18 0.0122 0.0492 2066996 IFLab1_002688 CC(=O)NCCCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K05 compound treatment 0.328 0.00175 0.07 0.322 -0.00319 -0.07 0.0015 0.0155 2066997 IFLab1_002689 CC(NC(=O)C)c1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K06 compound treatment 0.344 0.0177 0.7 0.326 8.12E-4 0.02 0.5055 0.7241 2066998 IFLab1_002690 O=C(Cc1ccccc1)NCCCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K07 compound treatment 0.337 0.0107 0.42 0.326 8.12E-4 0.02 0.3109 0.735 2066999 IFLab1_002691 CC(NC(=O)C)c1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K08 compound treatment 0.352 0.0257 1.01 0.342 0.0168 0.35 0.9647 0.9 2067000 IFLab1_002692 CCCn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K09 compound treatment 0.355 0.0288 1.13 0.34 0.0148 0.31 1.0185 0.8689 2067001 IFLab1_002693 Cn1c(CCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K10 compound treatment 0.403 0.0767 3.02 0.389 0.0638 1.34 3.078 0.9328 2067002 IFLab1_002694 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)COc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K11 compound treatment 0.346 0.0198 0.78 0.345 0.0198 0.41 0.8423 0.9568 2067003 IFLab1_002695 CCn1c(CCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K12 compound treatment 0.35 0.0238 0.93 0.344 0.0188 0.39 0.9387 0.9263 2067004 IFLab1_002696 CCC(=O)Nc1c(nc2ccccn12)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K13 compound treatment 0.345 0.0187 0.74 0.326 8.12E-4 0.02 0.5333 0.7232 2067005 IFLab1_002697 CCCCn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K14 compound treatment 0.336 0.00975 0.38 0.353 0.0278 0.58 0.6826 0.9795 2067006 IFLab1_002698 CC(C)(C)CC(=O)Nc1c(nc2ccccn12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K15 compound treatment 0.332 0.00575 0.23 0.326 8.12E-4 0.02 0.1719 0.7581 2067007 IFLab1_002699 CC(C)Cn1c(CCNC(=O)C(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K16 compound treatment 0.35 0.0238 0.93 0.351 0.0258 0.54 1.0422 0.9661 2067008 IFLab1_002700 O=C(CS(=O)(=O)c1c[nH]c2ccccc12)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K17 compound treatment 0.354 0.0278 1.09 0.346 0.0208 0.44 1.0795 0.9189 2067009 IFLab1_002701 CC(=C)Cn1c(CCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K18 compound treatment 0.343 0.0168 0.66 0.339 0.0138 0.29 0.6701 0.9317 2067010 IFLab1_002702 Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K19 compound treatment 0.324 -0.00225 -0.09 0.336 0.0108 0.23 0.0974 0.4011 2067011 IFLab1_002703 COc1ccc(cc1OC)C(=O)NCCCc2nc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K20 compound treatment 0.347 0.0208 0.82 0.349 0.0238 0.5 0.9292 0.972 2067012 IFLab1_002704 Fc1ccc(Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)NC4CCCCC4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K21 compound treatment 0.344 0.0177 0.7 0.342 0.0168 0.35 0.7423 0.9497 2067013 IFLab1_002705 CCn1c(CCCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K22 compound treatment 0.341 0.0147 0.58 0.343 0.0178 0.37 0.6737 0.9772 2067014 IFLab1_002706 O=C(CSc1nnc(o1)c2ccccc2)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K23 mock treatment 0.324 -0.00225 -0.09 0.324 -0.00119 -0.02 -0.0801 -0.872 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 K24 positive control 0.088 -0.238 -9.37 0.086 -0.239 -5.01 -10.1631 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L01 compound treatment 0.338 0.0118 0.46 0.336 0.0108 0.23 0.4867 0.9461 2067015 IFLab1_002707 Clc1cccc(c1)c2nnc(SCC(=O)NC3CCCCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L02 compound treatment 0.355 0.0288 1.13 0.34 0.0148 0.31 1.0185 0.8689 2067016 IFLab1_002708 O=C(Nc1nnc(o1)c2ccc3CCCCc3c2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L03 compound treatment 0.321 -0.00525 -0.21 0.326 8.12E-4 0.02 -0.1339 -0.6467 2067017 IFLab1_002709 CC1CC(C)CN(C1)C(=O)CSc2nnc(COc3ccc(Cl)cc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L04 compound treatment 0.341 0.0147 0.58 0.326 8.12E-4 0.02 0.4221 0.7275 2067018 IFLab1_002710 COc1ccc(OC)c2[nH]c(=O)c(CCNC(=O)c3ccc(F)c(F)c3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L05 compound treatment 0.336 0.00975 0.38 0.317 -0.00819 -0.17 0.1499 0.357 2067019 IFLab1_002711 O=C(CSc1ncnc2c3ccccc3oc12)Nc4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L06 compound treatment 0.326 -2.5E-4 -0.01 0.321 -0.00419 -0.09 -0.0689 -0.7815 2067020 IFLab1_002712 CC(C)CC(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L07 compound treatment 0.324 -0.00225 -0.09 0.319 -0.00619 -0.13 -0.1541 -0.9827 2067021 IFLab1_002713 CC(C)Sc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L08 compound treatment 0.346 0.0198 0.78 0.336 0.0108 0.23 0.7091 0.8767 2067022 IFLab1_002714 Cc1ccc2cc(CCNC(=O)CCCc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L09 compound treatment 0.355 0.0288 1.13 0.35 0.0248 0.52 1.1665 0.9377 2067023 IFLab1_002715 O=C1CCCN2N=C(SC/C=C/c3ccccc3)SC2=N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L10 compound treatment 0.328 0.00175 0.07 0.324 -0.00119 -0.02 0.0311 0.4249 2067024 IFLab1_002716 COc1ccc2cc(CCNC(=O)C)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L11 compound treatment 0.345 0.0187 0.74 0.334 0.00881 0.18 0.6517 0.8576 2067025 IFLab1_002717 O=C(CSc1nccn1c2ccccc2)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L12 compound treatment 0.357 0.0308 1.21 0.337 0.0118 0.25 1.0297 0.8344 2067026 IFLab1_002718 Cc1ccc(C)c2[nH]c(=O)c(CCNC(=O)c3cccs3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L13 compound treatment 0.349 0.0227 0.89 0.328 0.00281 0.06 0.6741 0.752 2067027 IFLab1_002719 CCOc1ccccc1NC(=O)CSc2nccn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L14 compound treatment 0.335 0.00875 0.34 0.334 0.00881 0.18 0.3737 0.9573 2067028 IFLab1_002720 Cc1ccc2cc(CCNC(=O)CCc3ccccc3)c(=O)[nH]c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L15 compound treatment 0.347 0.0208 0.82 0.327 0.00181 0.04 0.6037 0.7392 2067029 IFLab1_002721 COc1ccc(cc1)n2ccnc2SCC(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L16 compound treatment 0.328 0.00175 0.07 0.336 0.0108 0.23 0.2086 0.8822 2067030 IFLab1_002722 Cc1ccc(C)c2[nH]c(=O)c(CCNS(=O)(=O)C)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L17 compound treatment 0.347 0.0208 0.82 0.33 0.00481 0.1 0.6481 0.7884 2067031 IFLab1_002723 Clc1cccc(c1)n2ccnc2SCC(=O)NC3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L18 compound treatment 0.327 7.5E-4 0.03 0.339 0.0138 0.29 0.2252 0.7752 2067032 IFLab1_002724 O=C(NCCn1ccc2ccccc12)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L19 compound treatment 0.357 0.0308 1.21 0.366 0.0408 0.85 1.4588 0.9855 2067033 IFLab1_002725 Fc1cccc2sc(NC(=O)c3cccs3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L20 compound treatment 0.341 0.0147 0.58 0.338 0.0128 0.27 0.5997 0.9386 2067034 IFLab1_002726 Brc1ccc(o1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L21 compound treatment 0.337 0.0107 0.42 0.327 0.00181 0.04 0.3257 0.7675 2067035 IFLab1_002727 CCOC(=O)C1CCN(Cc2cn3c(nnc3s2)c4ccc(Br)cc4)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L22 compound treatment 0.346 0.0198 0.78 0.34 0.0148 0.31 0.7683 0.9189 2067036 IFLab1_002728 O=C(NCCn1ccc2ccccc12)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L23 mock treatment 0.328 0.00175 0.07 0.326 8.12E-4 0.02 0.0607 0.8561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 L24 positive control 0.089 -0.237 -9.33 0.086 -0.239 -5.01 -10.1353 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M01 compound treatment 0.337 0.0107 0.42 0.333 0.00781 0.16 0.4145 0.9146 2067037 IFLab1_002729 COCC(=O)NC(C)c1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M02 compound treatment 0.328 0.00175 0.07 0.32 -0.00519 -0.11 -0.0281 -0.2187 2067038 IFLab1_002730 CCCCn1c(CCCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M03 compound treatment 0.33 0.00375 0.15 0.319 -0.00619 -0.13 0.0127 0.0647 2067039 IFLab1_002731 CC(C)n1c(nc2ccccc12)C(C)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M04 compound treatment 0.327 7.5E-4 0.03 0.314 -0.0112 -0.23 -0.1447 -0.6132 2067040 IFLab1_002732 CC(C)(C)C(=O)NCCCc1nc2ccccc2n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M05 compound treatment 0.338 0.0118 0.46 0.316 -0.00919 -0.19 0.1907 0.3811 2067041 IFLab1_002733 CCC(=O)NC(C)c1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M06 compound treatment 0.341 0.0147 0.58 0.325 -1.88E-4 0.0 0.4073 0.7023 2067042 IFLab1_002734 COc1ccc(cc1OC)C(=O)NCCCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M07 compound treatment 0.334 0.00775 0.3 0.337 0.0118 0.25 0.3903 0.9946 2067043 IFLab1_002735 CCC(=O)NC(C)c1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M08 compound treatment 0.336 0.00975 0.38 0.33 0.00481 0.1 0.3423 0.8636 2067044 IFLab1_002736 CCCCn1c(nc2ccccc12)C(Cc3ccccc3)NC(=O)COC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M09 compound treatment 0.338 0.0118 0.46 0.332 0.00681 0.14 0.4275 0.8842 2067045 IFLab1_002737 COCC(=O)NCCc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M10 compound treatment 0.388 0.0617 2.43 0.378 0.0528 1.11 2.4982 0.9365 2067046 IFLab1_002738 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M11 compound treatment 0.35 0.0238 0.93 0.348 0.0228 0.48 0.9979 0.9515 2067047 IFLab1_002739 CCn1c(CCNC(=O)c2ccc(OC)c(OC)c2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M12 compound treatment 0.364 0.0377 1.48 0.338 0.0128 0.27 1.2391 0.8215 2067048 IFLab1_002740 CCCCC(=O)Nc1c(nc2ccccn12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M13 compound treatment 0.333 0.00675 0.27 0.341 0.0158 0.33 0.4216 0.994 2067049 IFLab1_002741 CCCCn1c(CCNC(=O)Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M14 compound treatment 0.335 0.00875 0.34 0.358 0.0328 0.69 0.7288 0.9489 2067050 IFLab1_002742 O=C(Nc1c(nc2ccccn12)c3ccccc3)C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M15 compound treatment 0.332 0.00575 0.23 0.342 0.0168 0.35 0.4086 0.9771 2067051 IFLab1_002743 CC(C)Cn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M16 compound treatment 0.341 0.0147 0.58 0.344 0.0188 0.39 0.6885 0.9822 2067052 IFLab1_002744 Fc1cccc(CS(=O)(=O)c2c[nH]c3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M17 compound treatment 0.343 0.0168 0.66 0.345 0.0198 0.41 0.7589 0.9751 2067053 IFLab1_002745 CC(=O)NCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M18 compound treatment 0.333 0.00675 0.27 0.348 0.0228 0.48 0.5252 0.9616 2067054 IFLab1_002746 CCn1cc(c2ccccc12)S(=O)(=O)CC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M19 compound treatment 0.339 0.0127 0.5 0.344 0.0188 0.39 0.6328 0.9928 2067055 IFLab1_002747 Cn1c(CCCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M20 compound treatment 0.353 0.0267 1.05 0.336 0.0108 0.23 0.9037 0.84 2067056 IFLab1_002748 Cc1ccccc1Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)N4CCCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M21 compound treatment 0.334 0.00775 0.3 0.35 0.0248 0.52 0.5826 0.9677 2067057 IFLab1_002749 CCCn1c(CCCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M22 compound treatment 0.343 0.0168 0.66 0.349 0.0238 0.5 0.818 0.9905 2067058 IFLab1_002750 O=C(CSc1nnc(o1)c2ccccc2)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M23 mock treatment 0.333 0.00675 0.27 0.311 -0.0142 -0.3 -0.0223 -0.0559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 M24 positive control 0.091 -0.235 -9.25 0.088 -0.237 -4.96 -10.0501 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N01 compound treatment 0.333 0.00675 0.27 0.329 0.00381 0.08 0.2441 0.8807 2067059 IFLab1_002751 CC1CCN(CC1)C(=O)CSc2nnc(Cc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N02 compound treatment 0.332 0.00575 0.23 0.32 -0.00519 -0.11 0.0831 0.3314 2067060 IFLab1_002752 O=C(Nc1nnc(o1)c2ccc3CCCCc3c2)C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N03 compound treatment 0.346 0.0198 0.78 0.319 -0.00619 -0.13 0.4575 0.5812 1987190 IFLab1_002753 CC1CCCCN1C(=O)CSc2nnc(COc3ccc(Cl)cc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N04 compound treatment 0.334 0.00775 0.3 0.329 0.00381 0.08 0.2719 0.8631 2067061 IFLab1_002754 Cc1ccc2cc(CCNC(=O)COc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N05 compound treatment 0.334 0.00775 0.3 0.327 0.00181 0.04 0.2423 0.789 2067062 IFLab1_002755 NC(=O)CSc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N06 compound treatment 0.33 0.00375 0.15 0.329 0.00381 0.08 0.1607 0.9584 2067063 IFLab1_002756 CC(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N07 compound treatment 0.354 0.0278 1.09 0.362 0.0368 0.77 1.3162 0.9855 2067064 IFLab1_002757 COC(=O)c1ccc(CSc2ncnc3c4ccccc4oc23)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N08 compound treatment 0.347 0.0208 0.82 0.349 0.0238 0.5 0.9292 0.972 2067065 IFLab1_002758 COc1ccc2cc(CCNC(=O)Cc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N09 compound treatment 0.328 0.00175 0.07 0.35 0.0248 0.52 0.4158 0.7939 2067066 IFLab1_002759 O=C(CSc1nccn1c2ccccc2)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N10 compound treatment 0.342 0.0158 0.62 0.343 0.0178 0.37 0.7015 0.9705 2067067 IFLab1_002760 COc1ccc2cc(CCNC(=O)C(C)C)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N11 compound treatment 0.33 0.00375 0.15 0.335 0.00981 0.21 0.2495 0.9868 2067068 IFLab1_002761 FC(F)(F)Oc1ccc(NC(=O)CSc2nccn2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N12 compound treatment 0.349 0.0227 0.89 0.346 0.0208 0.44 0.9405 0.9453 2067069 IFLab1_002762 CCC(CC)C(=O)NCCc1cc2c(C)ccc(C)c2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N13 compound treatment 0.348 0.0217 0.86 0.347 0.0218 0.46 0.9275 0.9568 2067070 IFLab1_002763 O=C(CSc1nccn1c2ccccc2)NCc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N14 compound treatment 0.349 0.0227 0.89 0.349 0.0238 0.5 0.9849 0.9618 2067071 IFLab1_002764 Cc1ccc2cc(CCNC(=O)C3CCCCC3)c(=O)[nH]c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N15 compound treatment 0.344 0.0177 0.7 0.339 0.0138 0.29 0.6979 0.9239 2067072 IFLab1_002765 COc1ccc(cc1)n2ccnc2SCC(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N16 compound treatment 0.331 0.00475 0.19 0.342 0.0168 0.35 0.3808 0.9561 2067073 IFLab1_002766 CCCS(=O)(=O)NCCc1cc2ccc(C)c(C)c2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N17 compound treatment 0.349 0.0227 0.89 0.339 0.0138 0.29 0.8369 0.8903 2067074 IFLab1_002767 CCc1nnc(NC(=O)CSc2nccn2c3ccc(Cl)cc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N18 compound treatment 0.346 0.0198 0.78 0.346 0.0208 0.44 0.8571 0.9626 2067075 IFLab1_002768 O=C(Cc1cccs1)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N19 compound treatment 0.353 0.0267 1.05 0.354 0.0288 0.6 1.17 0.9651 2067076 IFLab1_002769 Fc1cccc2sc(NC(=O)c3ccco3)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N20 compound treatment 0.351 0.0248 0.97 0.345 0.0198 0.41 0.9813 0.9277 2067077 IFLab1_002770 CCOc1ccc(cc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N21 compound treatment 0.351 0.0248 0.97 0.344 0.0188 0.39 0.9665 0.9207 2067078 IFLab1_002771 CC1CCN(Cc2cn3c(nnc3s2)c4ccc(Br)cc4)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N22 compound treatment 0.343 0.0168 0.66 0.342 0.0168 0.35 0.7145 0.9569 2067079 IFLab1_002772 Cc1cccc(c1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N23 mock treatment 0.333 0.00675 0.27 0.331 0.00581 0.12 0.2737 0.9374 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 N24 positive control 0.092 -0.234 -9.21 0.089 -0.236 -4.94 -10.0075 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O01 compound treatment 0.342 0.0158 0.62 0.332 0.00681 0.14 0.5387 0.8477 2067080 IFLab1_002773 COc1ccc(cc1OC)C(=O)NC(C)c2nc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O02 compound treatment 0.324 -0.00225 -0.09 0.314 -0.0112 -0.23 -0.2281 -0.9114 2067081 IFLab1_002774 CCCCn1c(CCCNC(=O)CC)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O03 compound treatment 0.318 -0.00825 -0.32 0.317 -0.00819 -0.17 -0.3505 -0.9555 2067082 IFLab1_002775 CCCC(=O)NC(C)c1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O04 compound treatment 0.328 0.00175 0.07 0.317 -0.00819 -0.17 -0.0725 -0.3927 2067083 IFLab1_002776 C=CCn1c(CCCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O05 compound treatment 0.321 -0.00525 -0.21 0.32 -0.00519 -0.11 -0.2227 -0.955 2067084 IFLab1_002777 CC(C)Cn1c(nc2ccccc12)C(C)NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O06 compound treatment 0.333 0.00675 0.27 0.321 -0.00419 -0.09 0.1257 0.4498 2067085 IFLab1_002778 O=C(NCCCc1nc2ccccc2[nH]1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O07 compound treatment 0.336 0.00975 0.38 0.324 -0.00119 -0.02 0.2535 0.6599 2067086 IFLab1_002779 CC(NC(=O)C(C)(C)C)c1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O08 compound treatment 0.35 0.0238 0.93 0.355 0.0298 0.62 1.1014 0.9808 1363058 IFLab1_002780 O=C(NC(Cc1ccccc1)c2nc3ccccc3[nH]2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O09 compound treatment 0.328 0.00175 0.07 0.33 0.00481 0.1 0.1199 0.9827 2067087 IFLab1_002781 Cn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O10 compound treatment 0.37 0.0437 1.72 0.356 0.0308 0.64 1.6723 0.9103 2067088 IFLab1_002782 CCOC(=O)c1[nH]c2ccccc2c1NC(=O)CC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O11 compound treatment 0.337 0.0107 0.42 0.334 0.00881 0.18 0.4293 0.9309 2067089 IFLab1_002783 CCCn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O12 compound treatment 0.354 0.0278 1.09 0.351 0.0258 0.54 1.1535 0.9474 2067090 IFLab1_002784 COc1ccc(cc1)c2nc3ccccn3c2NC(=O)CC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O13 compound treatment 0.345 0.0187 0.74 0.347 0.0218 0.46 0.844 0.9734 2067091 IFLab1_002785 CCCCn1c(CCNC(=O)c2cccs2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O14 compound treatment 0.331 0.00475 0.19 0.35 0.0248 0.52 0.4992 0.9047 2067092 IFLab1_002786 Cc1ccn2c(NC(=O)C(C)(C)C)c(nc2c1)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O15 compound treatment 0.353 0.0267 1.05 0.33 0.00481 0.1 0.8149 0.7713 2067093 IFLab1_002787 COc1ccc(cc1OC)C(=O)NCCc2nc3ccccc3n2CC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O16 compound treatment 0.347 0.0208 0.82 0.35 0.0248 0.52 0.944 0.9762 2067094 IFLab1_002788 Cc1ccccc1CS(=O)(=O)c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O17 compound treatment 0.34 0.0138 0.54 0.344 0.0188 0.39 0.6606 0.9879 2067095 IFLab1_002789 CC(C)(C)C(=O)NCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O18 compound treatment 0.344 0.0177 0.7 0.336 0.0108 0.23 0.6535 0.8907 2067096 IFLab1_002790 CCn1cc(c2ccccc12)S(=O)(=O)CC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O19 compound treatment 0.339 0.0127 0.5 0.342 0.0168 0.35 0.6033 0.985 2067097 IFLab1_002791 CCn1c(CCCNC(=O)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O20 compound treatment 0.368 0.0418 1.64 0.359 0.0338 0.71 1.6611 0.9292 2067098 IFLab1_002792 Cc1ccccc1Cn2cc(c3ccccc23)S(=O)(=O)CC(=O)Nc4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O21 compound treatment 0.35 0.0238 0.93 0.346 0.0208 0.44 0.9683 0.9397 1542607 IFLab1_002793 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4CCCCc4c3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O22 compound treatment 0.345 0.0187 0.74 0.34 0.0148 0.31 0.7405 0.9259 2067099 IFLab1_002794 CC1CCCCN1C(=O)CSc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O23 mock treatment 0.332 0.00575 0.23 0.327 0.00181 0.04 0.1867 0.8144 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 O24 positive control 0.095 -0.231 -9.09 0.091 -0.234 -4.9 -9.8945 -0.9579 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P01 compound treatment 0.356 0.0297 1.17 0.336 0.0108 0.23 0.9871 0.8285 2067100 IFLab1_002795 O=C(CSc1nnc(Cc2ccccc2)o1)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P02 compound treatment 0.34 0.0138 0.54 0.325 -1.88E-4 0.0 0.3795 0.702 2067101 IFLab1_002796 CC(C)(C)C(=O)Nc1nnc(o1)c2ccc3CCCCc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P03 compound treatment 0.35 0.0238 0.93 0.329 0.00381 0.08 0.7167 0.7647 2067102 IFLab1_002797 O=C(CSc1nnc(COc2ccccc2)o1)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P04 compound treatment 0.37 0.0437 1.72 0.383 0.0578 1.21 2.0718 0.9852 2067103 IFLab1_002798 Cc1ccc2cc(CCNC(=O)/C=C\c3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P05 compound treatment 0.365 0.0388 1.52 0.358 0.0328 0.69 1.5629 0.9352 2067104 IFLab1_002799 O=C(CSc1ncnc2c3ccccc3oc12)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P06 compound treatment 0.38 0.0537 2.11 0.358 0.0328 0.69 1.9799 0.891 2067105 IFLab1_002800 Cc1ccc2cc(CCNC(=O)c3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P07 compound treatment 0.366 0.0398 1.56 0.37 0.0448 0.94 1.7682 0.9701 2067106 IFLab1_002801 CCOC(=O)CSc1ncnc2c3ccccc3oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P08 compound treatment 0.378 0.0517 2.03 0.386 0.0608 1.27 2.3386 0.9745 2067107 IFLab1_002802 COc1ccc2cc(CCNC(=O)COc3ccccc3)c(=O)[nH]c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P09 compound treatment 0.379 0.0527 2.07 0.377 0.0518 1.08 2.2332 0.9542 2067108 IFLab1_002803 Cc1nnc(NC(=O)CSc2nccn2c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P10 compound treatment 0.375 0.0488 1.92 0.38 0.0548 1.15 2.1664 0.9699 2067109 IFLab1_002804 CCC(CC)C(=O)NCCc1cc2ccc(OC)cc2[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P11 compound treatment 0.41 0.0838 3.29 0.415 0.0898 1.88 3.6574 0.9646 2067110 IFLab1_002805 Cc1ccc2nc(NC(=O)CSc3nccn3c4ccccc4)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P12 compound treatment 0.371 0.0447 1.76 0.374 0.0488 1.02 1.9664 0.9665 2067111 IFLab1_002806 CCC(C(=O)NCCc1cc2c(C)ccc(C)c2[nH]c1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P13 compound treatment 0.379 0.0527 2.07 0.382 0.0568 1.19 2.3072 0.9651 2067112 IFLab1_002807 CCc1nnc(NC(=O)CSc2nccn2c3cc(C)cc(C)c3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P14 compound treatment 0.371 0.0447 1.76 0.369 0.0438 0.92 1.8924 0.9538 2067113 IFLab1_002808 Cc1ccc2cc(CCNC(=O)c3ccc(F)c(F)c3)c(=O)[nH]c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P15 compound treatment 0.365 0.0388 1.52 0.366 0.0408 0.85 1.6812 0.9626 2067114 IFLab1_002809 COc1ccc(cc1)n2ccnc2SCC(=O)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P16 compound treatment 0.359 0.0328 1.29 0.36 0.0348 0.73 1.4256 0.9636 2067115 IFLab1_002810 COc1ccc(cc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P17 compound treatment 0.371 0.0447 1.76 0.374 0.0488 1.02 1.9664 0.9665 2067116 IFLab1_002811 Fc1ccccc1NC(=O)CSc2nccn2c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P18 compound treatment 0.365 0.0388 1.52 0.37 0.0448 0.94 1.7404 0.9728 2067117 IFLab1_002812 COc1ccc(/C=C/C(=O)NCCn2ccc3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P19 compound treatment 0.355 0.0288 1.13 0.359 0.0338 0.71 1.2996 0.9745 2067118 IFLab1_002813 CC(=O)Nc1ccc2n(C)c(=NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P20 compound treatment 0.362 0.0357 1.41 0.348 0.0228 0.48 1.3315 0.8969 2067119 IFLab1_002814 CC(=O)NCCn1ccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P21 compound treatment 0.355 0.0288 1.13 0.348 0.0228 0.48 1.1369 0.9265 2067120 IFLab1_002815 Brc1ccc(cc1)c2nnc3sc(CNC4CCCC4)cn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P22 compound treatment 0.352 0.0257 1.01 0.33 0.00481 0.1 0.7871 0.7736 2067121 IFLab1_002816 CC(C)(C)C(=O)NCCn1ccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P23 mock treatment 0.34 0.0138 0.54 0.344 0.0188 0.39 0.6606 0.9879 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1419 P24 positive control 0.099 -0.227 -8.94 0.094 -0.231 -4.84 -9.7389 -0.9585 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A01 compound treatment 0.347 0.0209 0.82 0.345 0.0166 0.35 0.8272 0.9261 2067122 IFLab1_002817 CCC(=O)NCCn1ccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A02 compound treatment 0.33 0.00394 0.15 0.316 -0.0124 -0.26 -0.0746 -0.2462 2067123 IFLab1_002818 O=C(CCn1c(=O)sc2ccccc12)NCCC3=CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A03 compound treatment 0.323 -0.00306 -0.12 0.339 0.0106 0.22 0.0712 0.2827 2067124 IFLab1_002819 Cc1cc2ccccc2n1CCNC(=O)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A04 compound treatment 0.333 0.00694 0.27 0.326 -0.00244 -0.05 0.1568 0.5651 2067125 IFLab1_002820 COc1ccc(NC(=O)CCn2c(=O)sc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A05 compound treatment 0.331 0.00494 0.19 0.327 -0.00144 -0.03 0.116 0.5905 2067126 IFLab1_002821 Cc1cc2ccccc2n1CCNC(=O)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A06 compound treatment 0.348 0.0219 0.86 0.327 -0.00144 -0.03 0.5886 0.682 2067127 IFLab1_002822 Fc1cc(F)c2c(c1)sc3nnc(c4ccccc4)n32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A07 compound treatment 0.321 -0.00506 -0.2 0.345 0.0166 0.35 0.1043 0.261 2067128 IFLab1_002823 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A08 compound treatment 0.329 0.00294 0.12 0.331 0.00256 0.05 0.1196 0.9391 2067129 IFLab1_002824 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)NC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A09 compound treatment 0.346 0.0199 0.78 0.315 -0.0134 -0.28 0.3555 0.4268 2067130 IFLab1_002825 Cc1cc(NC(=O)c2ccccc2)nc3c4ccccc4oc(=O)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A10 compound treatment 0.334 0.00794 0.31 0.324 -0.00444 -0.09 0.155 0.4761 2067131 IFLab1_002826 CCCCC(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A11 compound treatment 0.333 0.00694 0.27 0.358 0.0296 0.62 0.6303 0.9323 2067132 IFLab1_002827 CCOC(=O)C1C(CC(=CC1=O)c2ccco2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A12 compound treatment 0.357 0.0309 1.22 0.337 0.00856 0.18 0.9868 0.8026 2067133 IFLab1_002828 COc1ccc(cc1OC)C(=O)NCc2ccc3[nH]c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A13 compound treatment 0.33 0.00394 0.15 0.327 -0.00144 -0.03 0.0882 0.5593 2067134 IFLab1_002829 CC1CCCN(C1)C(=O)CSCC(=O)N=c2sc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A14 compound treatment 0.325 -0.00106 -0.04 0.328 -4.37E-4 -0.01 -0.036 -0.8421 2067135 IFLab1_002830 Cc1cc2cc(CNC(=O)Cc3cccs3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A15 compound treatment 0.329 0.00294 0.12 0.348 0.0196 0.41 0.3711 0.8725 2067136 IFLab1_002831 Cc1nc2sc(C(N3CCCCC3)c4ccccc4)c(O)n2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A16 compound treatment 0.343 0.0169 0.67 0.328 -4.37E-4 -0.01 0.4644 0.6973 1987774 IFLab1_002832 CCOC(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A17 compound treatment 0.326 -6.25E-5 0.0 0.325 -0.00344 -0.07 -0.0526 -0.7308 2067137 IFLab1_002833 COc1ccc(cc1)C(=O)NCC(N(C)C)c2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A18 compound treatment 0.337 0.0109 0.43 0.315 -0.0134 -0.28 0.1052 0.2048 2067138 IFLab1_002834 CC(C)CC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A19 compound treatment 0.329 0.00294 0.12 0.348 0.0196 0.41 0.3711 0.8725 2067139 IFLab1_002835 CN(Cc1ccccc1)C(=O)CCn2c(=O)oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A20 compound treatment 0.325 -0.00106 -0.04 0.327 -0.00144 -0.03 -0.0508 -0.987 2067140 IFLab1_002836 Cc1cc2cc(CNC(=O)c3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A21 compound treatment 0.342 0.0159 0.63 0.32 -0.00844 -0.18 0.3182 0.4888 2067141 IFLab1_002837 O=C(CCn1c(=O)oc2ccccc12)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A22 compound treatment 0.327 9.38E-4 0.04 0.323 -0.00544 -0.11 -0.0544 -0.4548 2067142 IFLab1_002838 Cc1cc2cc(CNC(=O)Cc3cccs3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A23 mock treatment 0.321 -0.00506 -0.2 0.348 0.0196 0.41 0.1487 0.3267 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 A24 positive control 0.079 -0.247 -9.71 0.078 -0.25 -5.24 -10.5746 -0.9581 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B01 compound treatment 0.348 0.0219 0.86 0.335 0.00656 0.14 0.707 0.8095 1987861 IFLab1_002839 CCOC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B02 compound treatment 0.325 -0.00106 -0.04 0.317 -0.0114 -0.24 -0.1988 -0.8182 2067143 IFLab1_002840 CCN1CCN(CC1)C(C(C)NC(=O)c2cccc(OC)c2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B03 compound treatment 0.347 0.0209 0.82 0.333 0.00456 0.1 0.6496 0.7839 2067144 IFLab1_002841 CC(C)CC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B04 compound treatment 0.327 9.38E-4 0.04 0.329 5.63E-4 0.01 0.0344 0.8887 2067145 IFLab1_002842 CCN1CCN(CC1)C(C(C)NC(=O)c2ccncc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B05 compound treatment 0.339 0.0129 0.51 0.338 0.00956 0.2 0.5012 0.9169 2067146 IFLab1_002843 O=C(NCc1ccc2[nH]c3CCCCc3c2c1)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B06 compound treatment 0.324 -0.00206 -0.08 0.33 0.00156 0.03 -0.0342 -0.3914 2067147 IFLab1_002844 CC(NS(=O)(=O)C)C(N1CCOCC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B07 compound treatment 0.335 0.00894 0.35 0.329 5.63E-4 0.01 0.2568 0.7304 2067148 IFLab1_002845 CCCS(=O)(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B08 compound treatment 0.34 0.0139 0.55 0.337 0.00856 0.18 0.5142 0.8918 2067149 IFLab1_002846 Cn1cccc1Cc2nnc(SCC(=O)N3CCCC3)n2CCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B09 compound treatment 0.33 0.00394 0.15 0.331 0.00256 0.05 0.1474 0.8996 1987731 IFLab1_002847 Cn1c(SCC(=O)N2CCCC2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B10 compound treatment 0.329 0.00294 0.12 0.342 0.0136 0.28 0.2824 0.9215 2067150 IFLab1_002848 CCn1c(nc2ccccc12)C3CN(Cc4ccccc4)C(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B11 compound treatment 0.344 0.0179 0.71 0.324 -0.00444 -0.09 0.433 0.6088 2067151 IFLab1_002849 CCn1c(SC)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B12 compound treatment 0.337 0.0109 0.43 0.341 0.0126 0.26 0.49 0.9721 2067152 IFLab1_002850 CCSc1nnc(Cn2c(=O)sc3ccccc23)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B13 compound treatment 0.334 0.00794 0.31 0.327 -0.00144 -0.03 0.1994 0.636 2067153 IFLab1_002851 COCCn1c(SC)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B14 compound treatment 0.337 0.0109 0.43 0.338 0.00956 0.2 0.4456 0.9394 2067154 IFLab1_002852 Cc1cc(NC(=O)CN2C(=O)CC(Sc3ccccc23)c4ccccc4)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B15 compound treatment 0.341 0.0149 0.59 0.338 0.00956 0.2 0.5568 0.8974 2067155 IFLab1_002853 COC(=O)CSc1nnc(c2c[nH]c3ccccc23)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B16 compound treatment 0.327 9.38E-4 0.04 0.326 -0.00244 -0.05 -0.01 -0.159 2067156 IFLab1_002854 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCN(CC2)c3ccccc3F)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B17 compound treatment 0.325 -0.00106 -0.04 0.341 0.0126 0.26 0.1563 0.5874 2067157 IFLab1_002855 COc1ccc(CC(=O)NC(C)C(N2CCOCC2)c3cccs3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B18 compound treatment 0.347 0.0209 0.82 0.344 0.0156 0.33 0.8124 0.9176 2067158 IFLab1_002856 O=C(Nc1ccccc1)c2cccn(OCc3ccccc3)c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B19 compound treatment 0.323 -0.00306 -0.12 0.333 0.00456 0.1 -0.0176 -0.1147 2067159 IFLab1_002857 COc1ccc(cc1OC)C(=O)NC(C)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B20 compound treatment 0.346 0.0199 0.78 0.347 0.0186 0.39 0.829 0.9475 2067160 IFLab1_002858 COc1ccccc1NC(=O)CSc2ncnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B21 compound treatment 0.34 0.0139 0.55 0.339 0.0106 0.22 0.5438 0.9203 1260122 IFLab1_002859 Cc1ccc(cc1C)c2nnc(N3CCOCC3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B22 compound treatment 0.333 0.00694 0.27 0.331 0.00256 0.05 0.2308 0.8302 2067161 IFLab1_002860 COC(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B23 mock treatment 0.331 0.00494 0.19 0.331 0.00256 0.05 0.1752 0.8699 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 B24 positive control 0.079 -0.247 -9.71 0.078 -0.25 -5.24 -10.5746 -0.9581 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C01 compound treatment 0.344 0.0179 0.71 0.336 0.00756 0.16 0.6106 0.8448 1987268 IFLab1_002861 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C02 compound treatment 0.328 0.00194 0.08 0.32 -0.00844 -0.18 -0.071 -0.3691 2067162 IFLab1_002862 CC1CCCCC1NC(=O)CCn2c(=O)sc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C03 compound treatment 0.319 -0.00706 -0.28 0.324 -0.00444 -0.09 -0.262 -0.8949 2067163 IFLab1_002863 Cc1cc2ccccc2n1CCNC(=O)Cc3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C04 compound treatment 0.334 0.00794 0.31 0.345 0.0166 0.35 0.4658 0.9986 2067164 IFLab1_002864 CCOC(=O)c1ccc(NC(=O)CCn2c(=O)sc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C05 compound treatment 0.317 -0.00906 -0.36 0.306 -0.0224 -0.47 -0.584 -0.9907 2067165 IFLab1_002865 CC(Oc1ccccc1)C(=O)NCCn2c(C)cc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C06 compound treatment 0.336 0.00994 0.39 0.336 0.00756 0.16 0.3882 0.9208 2067166 IFLab1_002866 CN(C1CCCCC1)C(=O)c2sc3nc(cn3c2C)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C07 compound treatment 0.335 0.00894 0.35 0.334 0.00556 0.12 0.3308 0.8936 2067167 IFLab1_002867 Cc1cc2ccccc2n1CCNS(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C08 compound treatment 0.379 0.0529 2.08 0.366 0.0376 0.79 2.0276 0.9113 2067168 IFLab1_002868 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)Nc4cccc(C)n4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C09 compound treatment 0.344 0.0179 0.71 0.34 0.0116 0.24 0.6698 0.8983 2067169 IFLab1_002869 CCC(CC)C(=O)Nc1cc(C)c2c(=O)oc3ccccc3c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C10 compound treatment 0.344 0.0179 0.71 0.336 0.00756 0.16 0.6106 0.8448 2067170 IFLab1_002870 CC(C)CC(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C11 compound treatment 0.334 0.00794 0.31 0.339 0.0106 0.22 0.377 0.9857 2067171 IFLab1_002871 CCOC(=O)C1C(CC(=CC1=O)c2ccco2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C12 compound treatment 0.337 0.0109 0.43 0.339 0.0106 0.22 0.4604 0.9521 2067172 IFLab1_002872 Cc1cc2cc(CNC(=O)c3ccc4OCOc4c3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C13 compound treatment 0.338 0.0119 0.47 0.321 -0.00744 -0.16 0.2218 0.4486 2067173 IFLab1_002873 CCn1c(=NC(=O)CSCC(=O)N2CCCc3ccccc23)sc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C14 compound treatment 0.336 0.00994 0.39 0.334 0.00556 0.12 0.3586 0.8796 2067174 IFLab1_002874 Cc1cc2cc(CNC(=O)CCc3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C15 compound treatment 0.34 0.0139 0.55 0.333 0.00456 0.1 0.455 0.818 2067175 IFLab1_002875 Cc1nc2sc(C(N3CCC(O)CC3)c4cccc(F)c4)c(O)n2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C16 compound treatment 0.336 0.00994 0.39 0.327 -0.00144 -0.03 0.255 0.6507 2067176 IFLab1_002876 C/C=C\C(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C17 compound treatment 0.326 -6.25E-5 0.0 0.338 0.00956 0.2 0.1398 0.6984 2067177 IFLab1_002877 CN(C)C(CNC(=O)c1cccs1)c2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C18 compound treatment 0.324 -0.00206 -0.08 0.338 0.00956 0.2 0.0842 0.3898 2067178 IFLab1_002878 CCC(CC)C(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C19 compound treatment 0.335 0.00894 0.35 0.337 0.00856 0.18 0.3752 0.9511 2067179 IFLab1_002879 O=C(CCn1c(=O)oc2ccccc12)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C20 compound treatment 0.327 9.38E-4 0.04 0.338 0.00956 0.2 0.1676 0.8235 2067180 IFLab1_002880 Cc1cc2cc(CNC(=O)c3ccc4OCOc4c3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C21 compound treatment 0.337 0.0109 0.43 0.334 0.00556 0.12 0.3864 0.8673 2067181 IFLab1_002881 COc1ccc(CCNC(=O)CCn2c(=O)oc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C22 compound treatment 0.335 0.00894 0.35 0.34 0.0116 0.24 0.4196 0.9834 2067182 IFLab1_002882 Cc1cc2cc(CNC(=O)CCc3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C23 mock treatment 0.327 9.38E-4 0.04 0.326 -0.00244 -0.05 -0.01 -0.159 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 C24 positive control 0.08 -0.246 -9.67 0.08 -0.248 -5.2 -10.5172 -0.9576 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D01 compound treatment 0.355 0.0289 1.14 0.343 0.0146 0.3 1.02 0.866 2067183 IFLab1_002883 C/C=C\C(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D02 compound treatment 0.334 0.00794 0.31 0.322 -0.00644 -0.13 0.1254 0.369 2067184 IFLab1_002884 CCN1CCN(CC1)C(C(C)NC(=O)c2ccc3OCOc3c2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D03 compound treatment 0.353 0.0269 1.06 0.355 0.0266 0.56 1.142 0.9547 2067185 IFLab1_002885 CCC(CC)C(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D04 compound treatment 0.336 0.00994 0.39 0.339 0.0106 0.22 0.4326 0.9636 2067186 IFLab1_002886 CCN1CCN(CC1)C(C(C)NC(=O)c2ccc(cc2)N(C)C)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D05 compound treatment 0.347 0.0209 0.82 0.335 0.00656 0.14 0.6792 0.8138 2067187 IFLab1_002887 C/C=C\C(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D06 compound treatment 0.342 0.0159 0.63 0.336 0.00756 0.16 0.555 0.8587 2067188 IFLab1_002888 CC(NS(=O)(=O)c1ccccc1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D07 compound treatment 0.34 0.0139 0.55 0.343 0.0146 0.3 0.603 0.9616 2067189 IFLab1_002889 CN(C)S(=O)(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D08 compound treatment 0.342 0.0159 0.63 0.34 0.0116 0.24 0.6142 0.9143 2067190 IFLab1_002890 Cn1cccc1Cc2nnc(SCC(=O)N)n2CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D09 compound treatment 0.341 0.0149 0.59 0.34 0.0116 0.24 0.5864 0.9231 2067191 IFLab1_002891 Cn1c(SCC(=O)N)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D10 compound treatment 0.347 0.0209 0.82 0.338 0.00956 0.2 0.7236 0.8541 2067192 IFLab1_002892 CCCn1c(nc2ccccc12)C3CN(Cc4ccccc4)C(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D11 compound treatment 0.342 0.0159 0.63 0.343 0.0146 0.3 0.6586 0.9451 2067193 IFLab1_002893 CCSc1nnc(c2c[nH]c3ccccc23)n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D12 compound treatment 0.334 0.00794 0.31 0.339 0.0106 0.22 0.377 0.9857 1332791 IFLab1_002894 CN1C(=O)CC(Sc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D13 compound treatment 0.32 -0.00606 -0.24 0.341 0.0126 0.26 0.0173 0.0489 2067194 IFLab1_002895 COCCn1c(SC(C)C)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D14 compound treatment 0.332 0.00594 0.23 0.33 0.00156 0.03 0.1882 0.7984 2067195 IFLab1_002896 COc1ccc(cc1OC)C2CC(=O)N(CC(=O)N)c3ccccc3S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D15 compound treatment 0.354 0.0279 1.1 0.345 0.0166 0.35 1.0218 0.8871 2067196 IFLab1_002897 COC(=O)C(C)Sc1nnc(c2c[nH]c3ccccc23)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D16 compound treatment 0.336 0.00994 0.39 0.337 0.00856 0.18 0.403 0.9375 2067197 IFLab1_002898 CCOC(=O)c1[nH]c(C)c(C(=O)NC)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D17 compound treatment 0.336 0.00994 0.39 0.334 0.00556 0.12 0.3586 0.8796 2067198 IFLab1_002899 CC(NC(=O)Cc1ccc(F)cc1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D18 compound treatment 0.347 0.0209 0.82 0.338 0.00956 0.2 0.7236 0.8541 2067199 IFLab1_002900 COc1ccccc1NC(=O)c2cccn(OCc3ccccc3)c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D19 compound treatment 0.34 0.0139 0.55 0.338 0.00956 0.2 0.529 0.9068 2067200 IFLab1_002901 CC(NC(=O)c1c(F)cccc1F)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D20 compound treatment 0.344 0.0179 0.71 0.342 0.0136 0.28 0.6994 0.92 2067201 IFLab1_002902 CCOc1ccccc1NC(=O)CSc2ncnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D21 compound treatment 0.338 0.0119 0.47 0.334 0.00556 0.12 0.4142 0.8565 2067202 IFLab1_002903 CC(C)OC(=O)NC1(Oc2ccccc2O1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D22 compound treatment 0.335 0.00894 0.35 0.339 0.0106 0.22 0.4048 0.975 2067203 IFLab1_002904 CC(=O)Nc1cccc(NC(=O)CSc2ncnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D23 mock treatment 0.33 0.00394 0.15 0.325 -0.00344 -0.07 0.0586 0.3433 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 D24 positive control 0.08 -0.246 -9.67 0.081 -0.247 -5.18 -10.5024 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E01 compound treatment 0.328 0.00194 0.08 0.326 -0.00244 -0.05 0.0178 0.1941 2067204 IFLab1_002905 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E02 compound treatment 0.32 -0.00606 -0.24 0.315 -0.0134 -0.28 -0.3674 -0.9966 2067205 IFLab1_002906 O=C(CCn1c(=O)sc2ccccc12)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E03 compound treatment 0.327 9.38E-4 0.04 0.323 -0.00544 -0.11 -0.0544 -0.4548 2067206 IFLab1_002907 Cc1cc2ccccc2n1CCNC(=O)C3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E04 compound treatment 0.334 0.00794 0.31 0.328 -4.37E-4 -0.01 0.2142 0.6861 2067207 IFLab1_002908 O=C(CCn1c(=O)sc2ccccc12)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E05 compound treatment 0.335 0.00894 0.35 0.332 0.00356 0.07 0.3012 0.8385 2067208 IFLab1_002909 Cc1cc2ccccc2n1CCNC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E06 compound treatment 0.336 0.00994 0.39 0.346 0.0176 0.37 0.5362 0.9995 2067209 IFLab1_002910 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E07 compound treatment 0.339 0.0129 0.51 0.33 0.00156 0.03 0.3828 0.751 2067210 IFLab1_002911 Cc1cc2ccccc2n1CCNS(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E08 compound treatment 0.349 0.0229 0.9 0.338 0.00956 0.2 0.7792 0.8435 2067211 IFLab1_002912 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E09 compound treatment 0.359 0.0329 1.3 0.349 0.0206 0.43 1.22 0.894 2067212 IFLab1_002913 CCC(=O)Nc1cc(C)c2c(=O)oc3ccccc3c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E10 compound treatment 0.344 0.0179 0.71 0.347 0.0186 0.39 0.7734 0.9605 2067213 IFLab1_002914 CCC(CC)C(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E11 compound treatment 0.344 0.0179 0.71 0.344 0.0156 0.33 0.729 0.9384 2067214 IFLab1_002915 COc1ccc2n(C)c(=NC(=O)CSC(=O)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E12 compound treatment 0.342 0.0159 0.63 0.349 0.0206 0.43 0.7474 0.9832 2067215 IFLab1_002916 COc1ccc(/C=C\C(=O)NCc2ccc3[nH]c(C)cc3c2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E13 compound treatment 0.34 0.0139 0.55 0.347 0.0186 0.39 0.6622 0.9858 2067216 IFLab1_002917 CCn1c(=NC(=O)CSCC(=O)Nc2nccs2)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E14 compound treatment 0.338 0.0119 0.47 0.338 0.00956 0.2 0.4734 0.9278 2067217 IFLab1_002918 Cc1cc2cc(CNC(=O)CCCc3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E15 compound treatment 0.338 0.0119 0.47 0.341 0.0126 0.26 0.5178 0.9625 2067218 IFLab1_002919 Cc1nc2sc(C(N3CCOCC3)c4cccc(F)c4)c(O)n2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E16 compound treatment 0.344 0.0179 0.71 0.339 0.0106 0.22 0.655 0.8862 1987817 IFLab1_002920 Cc1cc2cc(CNC(=O)CCC(=O)O)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E17 compound treatment 0.333 0.00694 0.27 0.334 0.00556 0.12 0.2752 0.9279 2067219 IFLab1_002921 COc1ccccc1C(=O)NCC(N(C)C)c2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E18 compound treatment 0.341 0.0149 0.59 0.332 0.00356 0.07 0.468 0.7905 2067220 IFLab1_002922 Cc1cc2cc(CNC(=O)C3CC3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E19 compound treatment 0.338 0.0119 0.47 0.331 0.00256 0.05 0.3698 0.7828 2067221 IFLab1_002923 Clc1ccccc1N2CCN(CC2)C(=O)CCn3c(=O)oc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E20 compound treatment 0.34 0.0139 0.55 0.338 0.00956 0.2 0.529 0.9068 2067222 IFLab1_002924 COc1cc(cc(OC)c1OC)C(=O)NCc2ccc3n(C)c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E21 compound treatment 0.34 0.0139 0.55 0.336 0.00756 0.16 0.4994 0.8755 2067223 IFLab1_002925 CCN(C(=O)CCn1c(=O)oc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E22 compound treatment 0.34 0.0139 0.55 0.346 0.0176 0.37 0.6474 0.9811 2067224 IFLab1_002926 Cc1cc2cc(CNC(=O)CCCc3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E23 mock treatment 0.329 0.00294 0.12 0.323 -0.00544 -0.11 0.0012 0.0075 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 E24 positive control 0.081 -0.245 -9.64 0.082 -0.246 -5.16 -10.4598 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F01 compound treatment 0.325 -0.00106 -0.04 0.329 5.63E-4 0.01 -0.0212 -0.4888 2067225 IFLab1_002927 Cc1cc2cc(CNC(=O)CCC(=O)O)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F02 compound treatment 0.322 -0.00406 -0.16 0.32 -0.00844 -0.18 -0.2378 -0.9987 2067226 IFLab1_002928 CCN1CCN(CC1)C(C(C)NC(=O)c2ccc(F)cc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F03 compound treatment 0.321 -0.00506 -0.2 0.329 5.63E-4 0.01 -0.1324 -0.6641 2067227 IFLab1_002929 O=C(NCc1ccc2[nH]c3CCCCc3c2c1)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F04 compound treatment 0.327 9.38E-4 0.04 0.32 -0.00844 -0.18 -0.0988 -0.5477 2067228 IFLab1_002930 CC(C)CC(=O)NC(C)C(N1CCN(CC1)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F05 compound treatment 0.324 -0.00206 -0.08 0.33 0.00156 0.03 -0.0342 -0.3914 2067229 IFLab1_002931 OC(=O)CCC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F06 compound treatment 0.335 0.00894 0.35 0.325 -0.00344 -0.07 0.1976 0.5509 2067230 IFLab1_002932 CC(NS(=O)(=O)C)C(N1CCN(C)CC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F07 compound treatment 0.342 0.0159 0.63 0.337 0.00856 0.18 0.5698 0.8743 2067231 IFLab1_002933 Cc1cc2cc(CNS(=O)(=O)c3ccc(C)cc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F08 compound treatment 0.343 0.0169 0.67 0.343 0.0146 0.3 0.6864 0.9372 2067232 IFLab1_002934 Cn1cccc1Cc2nnc(SCC(=O)N3CCCCC3)n2c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F09 compound treatment 0.341 0.0149 0.59 0.324 -0.00444 -0.09 0.3496 0.588 2067233 IFLab1_002935 Cn1c(SCC(=O)Nc2ccc(F)cc2F)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F10 compound treatment 0.329 0.00294 0.12 0.336 0.00756 0.16 0.1936 0.988 2067234 IFLab1_002936 COc1ccc(OC)c(c1)N2CC(CC2=O)c3nc4ccccc4n3CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F11 compound treatment 0.341 0.0149 0.59 0.332 0.00356 0.07 0.468 0.7905 2067235 IFLab1_002937 CCn1c(SCC(=O)N2CCC(C)CC2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F12 compound treatment 0.336 0.00994 0.39 0.324 -0.00444 -0.09 0.2106 0.5244 2067236 IFLab1_002938 CCN1C(=O)CC(Sc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F13 compound treatment 0.345 0.0189 0.74 0.341 0.0126 0.26 0.7124 0.9022 2067237 IFLab1_002939 COCCn1c(SCc2ccccc2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F14 compound treatment 0.333 0.00694 0.27 0.33 0.00156 0.03 0.216 0.7862 2067238 IFLab1_002940 COc1cc(cc(OC)c1OC)C2CC(=O)N(C)c3ccccc3S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F15 compound treatment 0.343 0.0169 0.67 0.333 0.00456 0.1 0.5384 0.8003 2067239 IFLab1_002941 CC(C)C(=O)NC(C)C(N1CCOCC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F16 compound treatment 0.348 0.0219 0.86 0.347 0.0186 0.39 0.8846 0.9351 2067240 IFLab1_002942 CCOC(=O)c1[nH]c(C)c(C(=O)NC2CCCCC2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F17 compound treatment 0.348 0.0219 0.86 0.345 0.0166 0.35 0.855 0.9198 2067241 IFLab1_002943 CC(NC(=O)Cc1cccs1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F18 compound treatment 0.348 0.0219 0.86 0.346 0.0176 0.37 0.8698 0.9277 2067242 IFLab1_002944 FC(F)(F)c1ccccc1NC(=O)c2cccn(OCc3ccccc3)c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F19 compound treatment 0.342 0.0159 0.63 0.347 0.0186 0.39 0.7178 0.9736 2067243 IFLab1_002945 COc1ccc(CC(=O)NC(C)C(N2CCN(C)CC2)c3cccs3)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F20 compound treatment 0.335 0.00894 0.35 0.34 0.0116 0.24 0.4196 0.9834 2067244 IFLab1_002946 CCOc1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F21 compound treatment 0.345 0.0189 0.74 0.344 0.0156 0.33 0.7568 0.9312 2067245 IFLab1_002947 S=c1[nH]c(nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F22 compound treatment 0.334 0.00794 0.31 0.338 0.00956 0.2 0.3622 0.9769 2067246 IFLab1_002948 CC(=O)Nc1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F23 mock treatment 0.327 9.38E-4 0.04 0.331 0.00256 0.05 0.064 0.9833 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 F24 positive control 0.081 -0.245 -9.64 0.082 -0.246 -5.16 -10.4598 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G01 compound treatment 0.333 0.00694 0.27 0.339 0.0106 0.22 0.3492 0.9946 2067247 IFLab1_002949 O=C(NCCn1ccc2ccccc12)c3ccc(cc3)S(=O)(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G02 compound treatment 0.313 -0.0131 -0.51 0.311 -0.0174 -0.36 -0.6212 -0.986 2067248 IFLab1_002950 CC(NC(=O)CCn1c(=O)sc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G03 compound treatment 0.319 -0.00706 -0.28 0.311 -0.0174 -0.36 -0.4544 -0.9909 2067249 IFLab1_002951 Cc1cc2ccccc2n1CCNC(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G04 compound treatment 0.319 -0.00706 -0.28 0.322 -0.00644 -0.13 -0.2916 -0.9448 2067250 IFLab1_002952 O=C(CCn1c(=O)sc2ccccc12)NC3=NCCS3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G05 compound treatment 0.325 -0.00106 -0.04 0.317 -0.0114 -0.24 -0.1988 -0.8182 2067251 IFLab1_002953 CCC(=O)NCCn1c(C)cc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G06 compound treatment 0.324 -0.00206 -0.08 0.336 0.00756 0.16 0.0546 0.3068 2067252 IFLab1_002954 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G07 compound treatment 0.335 0.00894 0.35 0.345 0.0166 0.35 0.4936 1.0 2067253 IFLab1_002955 Cc1cc(NC(=O)Cc2ccccc2)nc3c4ccccc4oc(=O)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G08 compound treatment 0.343 0.0169 0.67 0.342 0.0136 0.28 0.6716 0.9277 2067254 IFLab1_002956 CN(C)CCNC(=O)c1sc2nc(cn2c1C)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G09 compound treatment 0.344 0.0179 0.71 0.332 0.00356 0.07 0.5514 0.7775 2067255 IFLab1_002957 COCC(=O)Nc1cc(C)c2c(=O)oc3ccccc3c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G10 compound treatment 0.339 0.0129 0.51 0.338 0.00956 0.2 0.5012 0.9169 2067256 IFLab1_002958 Cc1cc2cc(CNC(=O)C3CC3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G11 compound treatment 0.338 0.0119 0.47 0.335 0.00656 0.14 0.429 0.8772 2067257 IFLab1_002959 CC(=O)SCC(=O)N=c1sc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G12 compound treatment 0.338 0.0119 0.47 0.336 0.00756 0.16 0.4438 0.896 2067258 IFLab1_002960 Cc1cc2cc(CNC(=O)/C=C\c3ccc4OCOc4c3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G13 compound treatment 0.31 -0.0161 -0.63 0.318 -0.0104 -0.22 -0.601 -0.8994 2067259 IFLab1_002961 COc1ccc(cc1)C(=O)NCc2nnc(SC/C=C/c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G14 compound treatment 0.334 0.00794 0.31 0.335 0.00656 0.14 0.3178 0.932 2067260 IFLab1_002962 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCc2ccc3[nH]c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G15 compound treatment 0.339 0.0129 0.51 0.329 5.63E-4 0.01 0.368 0.7233 2067261 IFLab1_002963 CN1CCN(CC1)C(c2sc3nc(C)nn3c2O)c4cccc(F)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G16 compound treatment 0.319 -0.00706 -0.28 0.338 0.00956 0.2 -0.0549 -0.1603 2067262 IFLab1_002964 CC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G17 compound treatment 0.342 0.0159 0.63 0.335 0.00656 0.14 0.5402 0.8421 2067263 IFLab1_002965 CN(C)C(CNC(=O)c1ccco1)c2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G18 compound treatment 0.341 0.0149 0.59 0.339 0.0106 0.22 0.5716 0.9109 2067264 IFLab1_002966 Cc1cc2cc(CNC(=O)C3CCCC3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G19 compound treatment 0.331 0.00494 0.19 0.335 0.00656 0.14 0.2344 0.9856 2067265 IFLab1_002967 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCn3c(=O)oc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G20 compound treatment 0.325 -0.00106 -0.04 0.329 5.63E-4 0.01 -0.0212 -0.4888 2067266 IFLab1_002968 Cc1cc2cc(CNC(=O)/C=C\c3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G21 compound treatment 0.337 0.0109 0.43 0.335 0.00656 0.14 0.4012 0.8887 2067267 IFLab1_002969 O=C(CCn1c(=O)oc2ccccc12)N(Cc3ccccc3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G22 compound treatment 0.335 0.00894 0.35 0.332 0.00356 0.07 0.3012 0.8385 2067268 IFLab1_002970 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCc2ccc3n(C)c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G23 mock treatment 0.324 -0.00206 -0.08 0.319 -0.00944 -0.2 -0.197 -0.9227 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 G24 positive control 0.081 -0.245 -9.64 0.082 -0.246 -5.16 -10.4598 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H01 compound treatment 0.341 0.0149 0.59 0.345 0.0166 0.35 0.6604 0.9683 2067269 IFLab1_002971 CC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H02 compound treatment 0.323 -0.00306 -0.12 0.317 -0.0114 -0.24 -0.2544 -0.9495 2067270 IFLab1_002972 CCN1CCN(CC1)C(C(C)NC(=O)c2c(F)cccc2F)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H03 compound treatment 0.337 0.0109 0.43 0.335 0.00656 0.14 0.4012 0.8887 2067271 IFLab1_002973 O=C(NCc1ccc2[nH]c3CCCCc3c2c1)C4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H04 compound treatment 0.35 0.0239 0.94 0.349 0.0206 0.43 0.9698 0.9371 2067272 IFLab1_002974 CC(NC(=O)Cc1cccs1)C(N2CCN(CC2)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H05 compound treatment 0.349 0.0229 0.9 0.347 0.0186 0.39 0.9124 0.9291 2067273 IFLab1_002975 CCCS(=O)(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H06 compound treatment 0.336 0.00994 0.39 0.342 0.0136 0.28 0.477 0.9877 2067274 IFLab1_002976 CC(NS(=O)(=O)c1ccccc1)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H07 compound treatment 0.361 0.0349 1.37 0.351 0.0226 0.47 1.3052 0.8986 2067275 IFLab1_002977 CCS(=O)(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H08 compound treatment 0.334 0.00794 0.31 0.336 0.00756 0.16 0.3326 0.9505 2067276 IFLab1_002978 Cn1cccc1Cc2nnc(SCC(=O)N)n2c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H09 compound treatment 0.339 0.0129 0.51 0.332 0.00356 0.07 0.4124 0.8022 2067277 IFLab1_002979 Cn1c(SCC(=O)NC2CCCC2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H10 compound treatment 0.33 0.00394 0.15 0.329 5.63E-4 0.01 0.1178 0.7587 2067278 IFLab1_002980 CCCCn1c(nc2ccccc12)C3CN(C(=O)C3)c4cc(OC)ccc4OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H11 compound treatment 0.339 0.0129 0.51 0.343 0.0146 0.3 0.5752 0.97 2067279 IFLab1_002981 CCn1c(SCC(=O)N)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H12 compound treatment 0.322 -0.00406 -0.16 0.328 -4.37E-4 -0.01 -0.1194 -0.7464 2067280 IFLab1_002982 CCCN1C(=O)CC(Sc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H13 compound treatment 0.343 0.0169 0.67 0.352 0.0236 0.49 0.8196 0.9891 2067281 IFLab1_002983 COc1ccc(cc1)n2c(SC)nnc2c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H14 compound treatment 0.334 0.00794 0.31 0.341 0.0126 0.26 0.4066 0.9964 2067282 IFLab1_002984 CCN1C(=O)CC(Sc2ccccc12)c3cc(OC)c(OC)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H15 compound treatment 0.338 0.0119 0.47 0.333 0.00456 0.1 0.3994 0.8339 2067283 IFLab1_002985 COc1cccc(c1)C(=O)NC(C)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H16 compound treatment 0.329 0.00294 0.12 0.334 0.00556 0.12 0.164 1.0 2067284 IFLab1_002986 CCCCN(C(=O)c1c(C)[nH]c(C(=O)OCC)c1C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H17 compound treatment 0.334 0.00794 0.31 0.337 0.00856 0.18 0.3474 0.9653 2067285 IFLab1_002987 CC(NC(=O)c1ccco1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H18 compound treatment 0.324 -0.00206 -0.08 0.322 -0.00644 -0.13 -0.1526 -0.9705 2067286 IFLab1_002988 Cc1ccc(NC(=O)c2cccn(OCc3ccccc3)c2=O)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H19 compound treatment 0.338 0.0119 0.47 0.334 0.00556 0.12 0.4142 0.8565 2067287 IFLab1_002989 CC(NC(=O)Cc1ccc(F)cc1)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H20 compound treatment 0.338 0.0119 0.47 0.336 0.00756 0.16 0.4438 0.896 2067288 IFLab1_002990 O=C(CSc1ncnc2ccccc12)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H21 compound treatment 0.338 0.0119 0.47 0.337 0.00856 0.18 0.4586 0.9128 1354034 IFLab1_002991 Clc1ccccc1c2nnc(NC(=O)CSC3=NCCS3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H22 compound treatment 0.338 0.0119 0.47 0.339 0.0106 0.22 0.4882 0.941 2067289 IFLab1_002992 O=C(CSc1ncnc2ccccc12)NC3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H23 mock treatment 0.33 0.00394 0.15 0.325 -0.00344 -0.07 0.0586 0.3433 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 H24 positive control 0.083 -0.243 -9.56 0.084 -0.244 -5.12 -10.3746 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I01 compound treatment 0.344 0.0179 0.71 0.34 0.0116 0.24 0.6698 0.8983 2067290 IFLab1_002993 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I02 compound treatment 0.34 0.0139 0.55 0.328 -4.37E-4 -0.01 0.381 0.6952 2067291 IFLab1_002994 COc1ccc(CCNC(=O)CCn2c(=O)sc3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I03 compound treatment 0.34 0.0139 0.55 0.335 0.00656 0.14 0.4846 0.8578 2067292 IFLab1_002995 Cc1cc2ccccc2n1CCNC(=O)c3ccc(Br)o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I04 compound treatment 0.339 0.0129 0.51 0.335 0.00656 0.14 0.4568 0.867 2067293 IFLab1_002996 O=C(CCn1c(=O)sc2ccccc12)Nc3ccon3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I05 compound treatment 0.349 0.0229 0.9 0.341 0.0126 0.26 0.8236 0.8767 2067294 IFLab1_002997 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCCn2c(C)cc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I06 compound treatment 0.34 0.0139 0.55 0.354 0.0256 0.53 0.7657 0.9999 2067295 IFLab1_002998 CC1CCCCN1C(=O)c2sc3nc(cn3c2C)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I07 compound treatment 0.351 0.0249 0.98 0.341 0.0126 0.26 0.8792 0.8661 2067296 IFLab1_002999 Cc1cc(NC(=O)C2CC2)nc3c4ccccc4oc(=O)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I08 compound treatment 0.35 0.0239 0.94 0.342 0.0136 0.28 0.8662 0.8811 2067297 IFLab1_003000 Cc1c(sc2nc(cn12)c3ccc(F)cc3)C(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I09 compound treatment 0.338 0.0119 0.47 0.345 0.0166 0.35 0.577 0.9889 2067298 IFLab1_003001 CCCn1cc(SCC(=O)N)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I10 compound treatment 0.355 0.0289 1.14 0.335 0.00656 0.14 0.9016 0.7867 2067299 IFLab1_003002 Cc1cc2cc(CNC(=O)C3CCCC3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I11 compound treatment 0.345 0.0189 0.74 0.343 0.0146 0.3 0.742 0.9223 2067300 IFLab1_003003 COc1ccc2n(C)c(=NC(=O)CSCC(=O)NC3CCCCC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I12 compound treatment 0.338 0.0119 0.47 0.33 0.00156 0.03 0.355 0.7545 2067301 IFLab1_003004 Cc1cc2cc(CNC(=O)COc3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I13 compound treatment 0.339 0.0129 0.51 0.351 0.0226 0.47 0.6935 0.9993 2067302 IFLab1_003005 Clc1ccc(OCC(=O)NCc2nnc(SC/C=C/c3ccccc3)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I14 compound treatment 0.346 0.0199 0.78 0.344 0.0156 0.33 0.7846 0.9243 2067303 IFLab1_003006 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)NCc2ccc3[nH]c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I15 compound treatment 0.33 0.00394 0.15 0.325 -0.00344 -0.07 0.0586 0.3433 2067304 IFLab1_003007 Cc1nc2sc(C(N3CCC(O)CC3)c4ccc(F)cc4)c(O)n2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I16 compound treatment 0.341 0.0149 0.59 0.325 -0.00344 -0.07 0.3644 0.6159 2067305 IFLab1_003008 CCC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I17 compound treatment 0.33 0.00394 0.15 0.336 0.00756 0.16 0.2214 0.9999 2067306 IFLab1_003009 CN1CCN(CC1)C(CNS(=O)(=O)c2ccccc2)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I18 compound treatment 0.325 -0.00106 -0.04 0.351 0.0226 0.47 0.3043 0.642 2067307 IFLab1_003010 Cc1cc2cc(CNC(=O)CC3CCCCC3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I19 compound treatment 0.344 0.0179 0.71 0.337 0.00856 0.18 0.6254 0.8595 2067308 IFLab1_003011 C=CCNC(=O)CCn1c(=O)oc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I20 compound treatment 0.345 0.0189 0.74 0.339 0.0106 0.22 0.6828 0.8791 2067309 IFLab1_003012 Cc1cc2cc(CNC(=O)COc3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I21 compound treatment 0.313 -0.0131 -0.51 0.31 -0.0184 -0.39 -0.636 -0.9901 1682201 IFLab1_003013 O=C(CCn1c(=O)oc2ccccc12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I22 compound treatment 0.335 0.00894 0.35 0.327 -0.00144 -0.03 0.2272 0.6442 2067310 IFLab1_003014 Cc1cc2cc(CNC(=O)c3ccc(cc3)S(=O)(=O)N4CCCC4)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I23 mock treatment 0.305 -0.0211 -0.83 0.314 -0.0144 -0.3 -0.7992 -0.9066 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 I24 positive control 0.083 -0.243 -9.56 0.085 -0.243 -5.09 -10.3598 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J01 compound treatment 0.339 0.0129 0.51 0.339 0.0106 0.22 0.516 0.9303 2067311 IFLab1_003015 CCC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J02 compound treatment 0.329 0.00294 0.12 0.333 0.00456 0.1 0.1492 0.9955 2067312 IFLab1_003016 CCN1CCN(CC1)C(C(C)NC(=O)Cc2ccc(OC)c(OC)c2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J03 compound treatment 0.352 0.0259 1.02 0.33 0.00156 0.03 0.7442 0.7294 2067313 IFLab1_003017 O=C(NCc1ccc2[nH]c3CCCCc3c2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J04 compound treatment 0.343 0.0169 0.67 0.343 0.0146 0.3 0.6864 0.9372 2067314 IFLab1_003018 CC(NC(=O)c1ccco1)C(N2CCN(CC2)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J05 compound treatment 0.334 0.00794 0.31 0.331 0.00256 0.05 0.2586 0.8166 2067315 IFLab1_003019 CN(C)S(=O)(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J06 compound treatment 0.327 9.38E-4 0.04 0.322 -0.00644 -0.13 -0.0692 -0.4954 2067316 IFLab1_003020 CCN1CCN(CC1)C(C(C)NS(=O)(=O)C)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J07 compound treatment 0.346 0.0199 0.78 0.344 0.0156 0.33 0.7846 0.9243 2067317 IFLab1_003021 CN(C)S(=O)(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J08 compound treatment 0.34 0.0139 0.55 0.343 0.0146 0.3 0.603 0.9616 2067318 IFLab1_003022 Cn1cccc1Cc2nnc(SCC(=O)Nc3ccccc3)n2c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J09 compound treatment 0.333 0.00694 0.27 0.331 0.00256 0.05 0.2308 0.8302 2067319 IFLab1_003023 Cn1c(SCC(=O)NCc2ccccc2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J10 compound treatment 0.338 0.0119 0.47 0.331 0.00256 0.05 0.3698 0.7828 2067320 IFLab1_003024 COc1ccc(Cl)cc1N2CC(CC2=O)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J11 compound treatment 0.353 0.0269 1.06 0.344 0.0156 0.33 0.9792 0.8837 2067321 IFLab1_003025 CCn1c(SCC(=O)Nc2ccccc2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J12 compound treatment 0.346 0.0199 0.78 0.326 -0.00244 -0.05 0.5182 0.6597 2067322 IFLab1_003026 O=C(CN1C(=O)CC(Sc2ccccc12)c3ccccc3)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J13 compound treatment 0.348 0.0219 0.86 0.343 0.0146 0.3 0.8254 0.9023 2067323 IFLab1_003027 CCSc1nnc(c2c[nH]c3ccccc23)n1c4ccc(OC)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J14 compound treatment 0.343 0.0169 0.67 0.338 0.00956 0.2 0.6124 0.8807 2067324 IFLab1_003028 CCOC(=O)c1[nH]c(C)c(C(=O)N(CC)CC)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J15 compound treatment 0.322 -0.00406 -0.16 0.339 0.0106 0.22 0.0433 0.159 2067325 IFLab1_003029 COc1ccc(C(=O)NC(C)C(N2CCOCC2)c3cccs3)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J16 compound treatment 0.337 0.0109 0.43 0.346 0.0176 0.37 0.564 0.9969 2067326 IFLab1_003030 CCOC(=O)c1[nH]c(C)c(C(=O)Nc2cc(C)cc(C)c2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J17 compound treatment 0.335 0.00894 0.35 0.338 0.00956 0.2 0.39 0.9644 2067327 IFLab1_003031 CC(NC(=O)c1cccs1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J18 compound treatment 0.335 0.00894 0.35 0.335 0.00656 0.14 0.3456 0.916 2067328 IFLab1_003032 O=C(Nc1nc2ccccc2s1)c3cccn(OCc4ccccc4)c3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J19 compound treatment 0.351 0.0249 0.98 0.346 0.0176 0.37 0.9532 0.9103 2067329 IFLab1_003033 CC(NC(=O)Cc1cccs1)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J20 compound treatment 0.343 0.0169 0.67 0.344 0.0156 0.33 0.7012 0.9459 2067330 IFLab1_003034 FC(F)(F)c1ccccc1NC(=O)CSc2ncnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J21 compound treatment 0.345 0.0189 0.74 0.347 0.0186 0.39 0.8012 0.954 2067331 IFLab1_003035 Brc1ccc(cc1)c2nnc(NC(=O)CSC3=NCCS3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J22 compound treatment 0.34 0.0139 0.55 0.337 0.00856 0.18 0.5142 0.8918 2067332 IFLab1_003036 O=C(CSc1ncnc2ccccc12)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J23 mock treatment 0.329 0.00294 0.12 0.331 0.00256 0.05 0.1196 0.9391 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 J24 positive control 0.084 -0.242 -9.52 0.086 -0.242 -5.07 -10.3172 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K01 compound treatment 0.341 0.0149 0.59 0.343 0.0146 0.3 0.6308 0.9533 2067333 IFLab1_003037 CCOc1ccc(CC(=O)NCCn2ccc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K02 compound treatment 0.32 -0.00606 -0.24 0.321 -0.00744 -0.16 -0.2786 -0.9787 2067334 IFLab1_003038 CC(CCc1ccccc1)NC(=O)CCn2c(=O)sc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K03 compound treatment 0.324 -0.00206 -0.08 0.314 -0.0144 -0.3 -0.271 -0.8662 2067335 IFLab1_003039 CC(=O)NCCn1c(C)cc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K04 compound treatment 0.332 0.00594 0.23 0.32 -0.00844 -0.18 0.0402 0.1374 2067336 IFLab1_003040 Cc1cc(NC(=O)CCn2c(=O)sc3ccccc23)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K05 compound treatment 0.323 -0.00306 -0.12 0.322 -0.00644 -0.13 -0.1804 -0.9984 2067337 IFLab1_003041 Cc1cc2ccccc2n1CCNC(=O)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K06 compound treatment 0.328 0.00194 0.08 0.328 -4.37E-4 -0.01 0.0474 0.6177 2067338 IFLab1_003042 CC1CN(CC(C)O1)C(=O)c2sc3nc(cn3c2C)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K07 compound treatment 0.326 -6.25E-5 0.0 0.331 0.00256 0.05 0.0362 0.674 2067339 IFLab1_003043 Cc1cc(NC(=O)C2CCCC2)nc3c4ccccc4oc(=O)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K08 compound treatment 0.344 0.0179 0.71 0.333 0.00456 0.1 0.5662 0.7956 2067340 IFLab1_003044 CC(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K09 compound treatment 0.34 0.0139 0.55 0.34 0.0116 0.24 0.5586 0.9325 2067341 IFLab1_003045 NC(=O)CSc1cn(Cc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K10 compound treatment 0.342 0.0159 0.63 0.339 0.0106 0.22 0.5994 0.9021 2067342 IFLab1_003046 Cc1cc2cc(CNC(=O)CC3CCCCC3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K11 compound treatment 0.343 0.0169 0.67 0.335 0.00656 0.14 0.568 0.8353 2067343 IFLab1_003047 COc1ccc2n(C)c(=NC(=O)CSCC(=O)N3CCc4ccccc34)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K12 compound treatment 0.343 0.0169 0.67 0.338 0.00956 0.2 0.6124 0.8807 2067344 IFLab1_003048 CC(Oc1ccccc1)C(=O)NCc2ccc3[nH]c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K13 compound treatment 0.348 0.0219 0.86 0.346 0.0176 0.37 0.8698 0.9277 2067345 IFLab1_003049 Fc1ccccc1C(=O)NCc2nnc(SC/C=C/c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K14 compound treatment 0.35 0.0239 0.94 0.348 0.0196 0.41 0.955 0.9305 2067346 IFLab1_003050 Cc1cc2cc(CNC(=O)c3ccc(cc3)S(=O)(=O)N4CCCC4)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K15 compound treatment 0.346 0.0199 0.78 0.343 0.0146 0.3 0.7698 0.9153 2067347 IFLab1_003051 CN1CCN(CC1)C(c2sc3nc(C)nn3c2O)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K16 compound treatment 0.35 0.0239 0.94 0.336 0.00756 0.16 0.7774 0.8146 2067348 IFLab1_003052 CCCC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K17 compound treatment 0.345 0.0189 0.74 0.345 0.0166 0.35 0.7716 0.9395 2067349 IFLab1_003053 O=S(=O)(NCC(N1CCOCC1)c2cccnc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K18 compound treatment 0.347 0.0209 0.82 0.35 0.0216 0.45 0.9012 0.9599 2067350 IFLab1_003054 Cc1cc2cc(CNC(=O)CCC3CCCC3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K19 compound treatment 0.325 -0.00106 -0.04 0.336 0.00756 0.16 0.0824 0.5032 2067351 IFLab1_003055 O=C(CCn1c(=O)oc2ccccc12)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K20 compound treatment 0.321 -0.00506 -0.2 0.338 0.00956 0.2 7.0E-4 0.0027 2067352 IFLab1_003056 CC(Oc1ccccc1)C(=O)NCc2ccc3n(C)c(C)cc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K21 compound treatment 0.342 0.0159 0.63 0.34 0.0116 0.24 0.6142 0.9143 2067353 IFLab1_003057 O=C(CCn1c(=O)oc2ccccc12)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K22 compound treatment 0.343 0.0169 0.67 0.32 -0.00844 -0.18 0.346 0.5023 2067354 IFLab1_003058 Cc1cc2cc(CNC(=O)c3ccco3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K23 mock treatment 0.327 9.38E-4 0.04 0.328 -4.37E-4 -0.01 0.0196 0.5158 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 K24 positive control 0.086 -0.24 -9.44 0.087 -0.241 -5.05 -10.2468 -0.9571 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L01 compound treatment 0.351 0.0249 0.98 0.347 0.0186 0.39 0.968 0.9178 2067355 IFLab1_003059 CCCC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L02 compound treatment 0.317 -0.00906 -0.36 0.314 -0.0144 -0.3 -0.4656 -0.9966 2067356 IFLab1_003060 CCN1CCN(CC1)C(C(C)NC(=O)Cc2ccc(F)cc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L03 compound treatment 0.349 0.0229 0.9 0.348 0.0196 0.41 0.9272 0.9361 2067357 IFLab1_003061 O=C(COc1ccccc1)NCc2ccc3[nH]c4CCCCc4c3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L04 compound treatment 0.333 0.00694 0.27 0.334 0.00556 0.12 0.2752 0.9279 2067358 IFLab1_003062 CC(NC(=O)c1ccncc1)C(N2CCN(CC2)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L05 compound treatment 0.345 0.0189 0.74 0.342 0.0136 0.28 0.7272 0.9126 2067359 IFLab1_003063 Cc1cc2cc(CNS(=O)(=O)c3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L06 compound treatment 0.322 -0.00406 -0.16 0.321 -0.00744 -0.16 -0.223 -0.9999 2067360 IFLab1_003064 CCN1CCN(CC1)C(C(C)NS(=O)(=O)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L07 compound treatment 0.362 0.0359 1.41 0.358 0.0296 0.62 1.4366 0.9313 2067361 IFLab1_003065 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2ccc3[nH]c4CCCCc4c3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L08 compound treatment 0.333 0.00694 0.27 0.323 -0.00544 -0.11 0.1124 0.3804 2067362 IFLab1_003066 Cc1ccc(N2CC(CC2=O)c3nc4ccccc4[nH]3)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L09 compound treatment 0.342 0.0159 0.63 0.331 0.00256 0.05 0.481 0.7648 2067363 IFLab1_003067 Cn1c(SCc2ccccc2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L10 compound treatment 0.324 -0.00206 -0.08 0.332 0.00356 0.07 -0.0046 -0.042 2067364 IFLab1_003068 CSc1nnc(Cn2c(=O)sc3ccccc23)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L11 compound treatment 0.337 0.0109 0.43 0.334 0.00556 0.12 0.3864 0.8673 2067365 IFLab1_003069 CCn1c(SCC(=O)NC2CCCC2)nnc1c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L12 compound treatment 0.335 0.00894 0.35 0.341 0.0126 0.26 0.4344 0.9898 2067366 IFLab1_003070 O=C(CN1C(=O)CC(Sc2ccccc12)c3ccccc3)NC4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L13 compound treatment 0.338 0.0119 0.47 0.345 0.0166 0.35 0.577 0.9889 2067367 IFLab1_003071 CCOc1ccc(cc1)n2c(SC)nnc2c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L14 compound treatment 0.334 0.00794 0.31 0.34 0.0116 0.24 0.3918 0.9921 2067368 IFLab1_003072 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCCCCC2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L15 compound treatment 0.33 0.00394 0.15 0.335 0.00656 0.14 0.2066 0.9982 2067369 IFLab1_003073 CC(NC(=O)c1ccc2OCOc2c1)C(N3CCOCC3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L16 compound treatment 0.336 0.00994 0.39 0.344 0.0156 0.33 0.5066 0.9959 2067370 IFLab1_003074 CCOC(=O)c1c(C)c(C(=O)NC2CCCCC2)c(C)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L17 compound treatment 0.341 0.0149 0.59 0.328 -4.37E-4 -0.01 0.4088 0.696 2067371 IFLab1_003075 CC(NC(=O)Oc1ccccc1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L18 compound treatment 0.338 0.0119 0.47 0.338 0.00956 0.2 0.4734 0.9278 2067372 IFLab1_003076 Cc1csc(NC(=O)c2cccn(OCc3ccccc3)c2=O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L19 compound treatment 0.34 0.0139 0.55 0.338 0.00956 0.2 0.529 0.9068 2067373 IFLab1_003077 CC(NC(=O)c1ccco1)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L20 compound treatment 0.34 0.0139 0.55 0.339 0.0106 0.22 0.5438 0.9203 2067374 IFLab1_003078 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2ncnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L21 compound treatment 0.346 0.0199 0.78 0.342 0.0136 0.28 0.755 0.9056 1355836 IFLab1_003079 COc1ccccc1c2nnc(NC(=O)CSC3=NCCS3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L22 compound treatment 0.337 0.0109 0.43 0.34 0.0116 0.24 0.4752 0.963 2067375 IFLab1_003080 O=C(CSc1ncnc2ccccc12)NCc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L23 mock treatment 0.33 0.00394 0.15 0.332 0.00356 0.07 0.1622 0.9439 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 L24 positive control 0.086 -0.24 -9.44 0.089 -0.239 -5.01 -10.2172 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M01 compound treatment 0.336 0.00994 0.39 0.326 -0.00244 -0.05 0.2402 0.6096 2067376 IFLab1_003081 O=C(NCCn1ccc2ccccc12)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M02 compound treatment 0.319 -0.00706 -0.28 0.319 -0.00944 -0.2 -0.336 -0.9861 2067377 IFLab1_003082 O=C(CCn1c(=O)sc2ccccc12)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M03 compound treatment 0.326 -6.25E-5 0.0 0.32 -0.00844 -0.18 -0.1266 -0.7169 2067378 IFLab1_003083 Cc1cc2ccccc2n1CCNC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M04 compound treatment 0.306 -0.0201 -0.79 0.319 -0.00944 -0.2 -0.6974 -0.8577 2067379 IFLab1_003084 Cc1nnc(NC(=O)CCn2c(=O)sc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M05 compound treatment 0.315 -0.0111 -0.43 0.328 -4.37E-4 -0.01 -0.314 -0.7218 2067380 IFLab1_003085 O=S(=O)(NCCn1ccc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M06 compound treatment 0.342 0.0159 0.63 0.326 -0.00244 -0.05 0.407 0.6474 2067381 IFLab1_003086 COC(CNC(=O)c1sc2nc(cn2c1C)c3ccccc3)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M07 compound treatment 0.345 0.0189 0.74 0.337 0.00856 0.18 0.6532 0.8529 2067382 IFLab1_003087 CC(C)CC(=O)Nc1cc(C)c2c(=O)oc3ccccc3c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M08 compound treatment 0.324 -0.00206 -0.08 0.345 0.0166 0.35 0.1877 0.5274 2067383 IFLab1_003088 CCC(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M09 compound treatment 0.341 0.0149 0.59 0.338 0.00956 0.2 0.5568 0.8974 2067384 IFLab1_003089 O=C(CSc1c[nH]c2ccccc12)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M10 compound treatment 0.353 0.0269 1.06 0.352 0.0236 0.49 1.0976 0.9395 2067385 IFLab1_003090 Cc1cc2cc(CNC(=O)CCC3CCCC3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M11 compound treatment 0.348 0.0219 0.86 0.342 0.0136 0.28 0.8106 0.8927 2067386 IFLab1_003091 COc1ccc2n(C)c(=NC(=O)CSCC(=O)N3CCCc4ccccc34)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M12 compound treatment 0.362 0.0359 1.41 0.344 0.0156 0.33 1.2294 0.8479 2067387 IFLab1_003092 Cc1cc2cc(CNC(=O)Cc3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M13 compound treatment 0.343 0.0169 0.67 0.344 0.0156 0.33 0.7012 0.9459 2067388 IFLab1_003093 O=C(NCc1nnc(SC/C=C/c2ccccc2)o1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M14 compound treatment 0.347 0.0209 0.82 0.345 0.0166 0.35 0.8272 0.9261 1628828 IFLab1_003094 Cc1cc2cc(CNC(=O)c3ccco3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M15 compound treatment 0.344 0.0179 0.71 0.34 0.0116 0.24 0.6698 0.8983 2067389 IFLab1_003095 CC1CCN(CC1)C(c2cccs2)c3sc4nc(C)nn4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M16 compound treatment 0.335 0.00894 0.35 0.342 0.0136 0.28 0.4492 0.9944 2067390 IFLab1_003096 CC(C)C(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M17 compound treatment 0.335 0.00894 0.35 0.34 0.0116 0.24 0.4196 0.9834 2067391 IFLab1_003097 CCN(CC)C(=O)CCn1c(=O)oc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M18 compound treatment 0.346 0.0199 0.78 0.346 0.0176 0.37 0.8142 0.9404 2067392 IFLab1_003098 COCC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M19 compound treatment 0.322 -0.00406 -0.16 0.338 0.00956 0.2 0.0286 0.1115 2067393 IFLab1_003099 CC(NC(=O)CCn1c(=O)oc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M20 compound treatment 0.359 0.0329 1.3 0.361 0.0326 0.68 1.3976 0.955 2067394 IFLab1_003100 Cc1cc2cc(CNC(=O)Cc3ccccc3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M21 compound treatment 0.344 0.0179 0.71 0.345 0.0166 0.35 0.7438 0.9465 2067395 IFLab1_003101 O=C(CCn1c(=O)oc2ccccc12)NC3=NCCS3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M22 compound treatment 0.361 0.0349 1.37 0.351 0.0226 0.47 1.3052 0.8986 2067396 IFLab1_003102 Cc1cc2cc(CNC(=O)c3cccs3)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M23 mock treatment 0.301 -0.0251 -0.99 0.308 -0.0204 -0.43 -0.9992 -0.9302 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 M24 positive control 0.088 -0.238 -9.36 0.091 -0.237 -4.97 -10.132 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N01 compound treatment 0.345 0.0189 0.74 0.343 0.0146 0.3 0.742 0.9223 2067397 IFLab1_003103 CC(C)C(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N02 compound treatment 0.375 0.0489 1.92 0.373 0.0446 0.93 2.02 0.9447 2067398 IFLab1_003104 CCN1CCN(CC1)C(C(C)NC(=O)Cc2cccs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N03 compound treatment 0.345 0.0189 0.74 0.341 0.0126 0.26 0.7124 0.9022 2067399 IFLab1_003105 O=C(Cc1ccccc1)NCc2ccc3[nH]c4CCCCc4c3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N04 compound treatment 0.333 0.00694 0.27 0.329 5.63E-4 0.01 0.2012 0.7369 2067400 IFLab1_003106 CC(NC(=O)Oc1ccccc1)C(N2CCN(CC2)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N05 compound treatment 0.365 0.0389 1.53 0.374 0.0456 0.95 1.7567 0.974 2067401 IFLab1_003107 Cc1cc2cc(CNS(=O)(=O)C)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N06 compound treatment 0.344 0.0179 0.71 0.33 0.00156 0.03 0.5218 0.7391 2067402 IFLab1_003108 CC(NS(=O)(=O)C)C(N1CCN(CC1)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N07 compound treatment 0.335 0.00894 0.35 0.334 0.00556 0.12 0.3308 0.8936 2067403 IFLab1_003109 CSc1nnc(c2c[nH]c3ccccc23)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N08 compound treatment 0.33 0.00394 0.15 0.331 0.00256 0.05 0.1474 0.8996 2067404 IFLab1_003110 O=C1CC(CN1Cc2ccccc2)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N09 compound treatment 0.351 0.0249 0.98 0.336 0.00756 0.16 0.8052 0.8107 2067405 IFLab1_003111 COC(=O)CSc1nnc(c2c[nH]c3ccccc23)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N10 compound treatment 0.342 0.0159 0.63 0.34 0.0116 0.24 0.6142 0.9143 2067406 IFLab1_003112 Cn1c(Cn2c(=O)sc3ccccc23)nnc1SC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N11 compound treatment 0.334 0.00794 0.31 0.345 0.0166 0.35 0.4658 0.9986 2067407 IFLab1_003113 CCn1c(SCC(=O)OC)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N12 compound treatment 0.336 0.00994 0.39 0.353 0.0246 0.51 0.6397 0.9908 2067408 IFLab1_003114 O=C(CN1C(=O)CC(Sc2ccccc12)c3ccccc3)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N13 compound treatment 0.345 0.0189 0.74 0.349 0.0206 0.43 0.8308 0.966 2067409 IFLab1_003115 CSc1nnc(c2c[nH]c3ccccc23)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N14 compound treatment 0.356 0.0299 1.18 0.354 0.0256 0.53 1.2106 0.9363 2067410 IFLab1_003116 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCCCC2C)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N15 compound treatment 0.32 -0.00606 -0.24 0.341 0.0126 0.26 0.0173 0.0489 2067411 IFLab1_003117 CC(NC(=O)c1ccc(F)cc1)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N16 compound treatment 0.33 0.00394 0.15 0.347 0.0186 0.39 0.3841 0.9187 2067412 IFLab1_003118 CCOC(=O)c1c(C)c(C(=O)NCc2ccccc2)c(C)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N17 compound treatment 0.335 0.00894 0.35 0.341 0.0126 0.26 0.4344 0.9898 2067413 IFLab1_003119 CC(C)C(=O)NC(C)C(N1CCN(C)CC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N18 compound treatment 0.34 0.0139 0.55 0.341 0.0126 0.26 0.5734 0.9434 2067414 IFLab1_003120 O=C(CSc1ncnc2ccccc12)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N19 compound treatment 0.343 0.0169 0.67 0.337 0.00856 0.18 0.5976 0.8665 2067415 IFLab1_003121 CC(NC(=O)c1cccs1)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N20 compound treatment 0.344 0.0179 0.71 0.343 0.0146 0.3 0.7142 0.9296 2067416 IFLab1_003122 CCOC(=O)c1ccccc1NC(=O)CSc2ncnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N21 compound treatment 0.349 0.0229 0.9 0.338 0.00956 0.2 0.7792 0.8435 2067417 IFLab1_003123 Cc1cc(C)c(c2nnc(NC(=O)CSC3=NCCS3)s2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N22 compound treatment 0.341 0.0149 0.59 0.337 0.00856 0.18 0.542 0.8827 2067418 IFLab1_003124 O=C(CSc1ncnc2ccccc12)NCC3CCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N23 mock treatment 0.334 0.00794 0.31 0.336 0.00756 0.16 0.3326 0.9505 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 N24 positive control 0.089 -0.237 -9.32 0.091 -0.237 -4.97 -10.1042 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O01 compound treatment 0.331 0.00494 0.19 0.32 -0.00844 -0.18 0.0124 0.0473 2067419 IFLab1_003125 Cc1cc2ccccc2n1CCNC(=O)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O02 compound treatment 0.311 -0.0151 -0.59 0.31 -0.0184 -0.39 -0.6916 -0.9785 2067420 IFLab1_003126 COc1ccccc1NC(=O)CCn2c(=O)sc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O03 compound treatment 0.31 -0.0161 -0.63 0.308 -0.0204 -0.43 -0.749 -0.982 2067421 IFLab1_003127 CC(C)C(=O)NCCn1c(C)cc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O04 compound treatment 0.32 -0.00606 -0.24 0.322 -0.00644 -0.13 -0.2638 -0.9635 2067422 IFLab1_003128 CC(=O)Nc1cccc(NC(=O)CCn2c(=O)sc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O05 compound treatment 0.328 0.00194 0.08 0.32 -0.00844 -0.18 -0.071 -0.3691 2067423 IFLab1_003129 COc1ccc(cc1)S(=O)(=O)NCCn2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O06 compound treatment 0.324 -0.00206 -0.08 0.326 -0.00244 -0.05 -0.0934 -0.975 2067424 IFLab1_003130 Cc1c(sc2nc(cn12)c3ccccc3)C(=O)NCCN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O07 compound treatment 0.327 9.38E-4 0.04 0.321 -0.00744 -0.16 -0.084 -0.5251 2067425 IFLab1_003131 CC(=O)Nc1cc(C)c2c(=O)oc3ccccc3c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O08 compound treatment 0.334 0.00794 0.31 0.33 0.00156 0.03 0.2438 0.7769 2067426 IFLab1_003132 CC(C)C(=O)NCc1ccc2[nH]c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O09 compound treatment 0.35 0.0239 0.94 0.337 0.00856 0.18 0.7922 0.8269 2067427 IFLab1_003133 CCOC(=O)C1C(CC(=CC1=O)c2ccco2)c3ccc(cc3)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O10 compound treatment 0.338 0.0119 0.47 0.336 0.00756 0.16 0.4438 0.896 2067428 IFLab1_003134 Cc1cc2cc(CNC(=O)c3ccccc3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O11 compound treatment 0.351 0.0249 0.98 0.348 0.0196 0.41 0.9828 0.925 2067429 IFLab1_003135 CCn1c(=NC(=O)CSCC(=O)N2CCN(CC2)c3ccccc3)sc4cc(F)ccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O12 compound treatment 0.352 0.0259 1.02 0.362 0.0336 0.7 1.2177 0.9834 2067430 IFLab1_003136 CCC(C(=O)NCc1ccc2[nH]c(C)cc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O13 compound treatment 0.345 0.0189 0.74 0.339 0.0106 0.22 0.6828 0.8791 2067431 IFLab1_003137 O=C(NCc1nnc(SC/C=C/c2ccccc2)o1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O14 compound treatment 0.355 0.0289 1.14 0.349 0.0206 0.43 1.1088 0.9115 2067432 IFLab1_003138 Cc1cc2cc(CNC(=O)c3cccs3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O15 compound treatment 0.343 0.0169 0.67 0.339 0.0106 0.22 0.6272 0.8939 2067433 IFLab1_003139 CC1CC(C)CN(C1)C(c2cccs2)c3sc4nc(C)nn4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O16 compound treatment 0.344 0.0179 0.71 0.338 0.00956 0.2 0.6402 0.8733 2067434 IFLab1_003140 CCCCC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O17 compound treatment 0.341 0.0149 0.59 0.339 0.0106 0.22 0.5716 0.9109 2067435 IFLab1_003141 CCCN(CCC)C(=O)CCn1c(=O)oc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O18 compound treatment 0.349 0.0229 0.9 0.354 0.0256 0.53 1.016 0.9689 2067436 IFLab1_003142 CCOCC(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O19 compound treatment 0.34 0.0139 0.55 0.336 0.00756 0.16 0.4994 0.8755 2067437 IFLab1_003143 O=C(CCn1c(=O)oc2ccccc12)NCc3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O20 compound treatment 0.365 0.0389 1.53 0.365 0.0366 0.77 1.6236 0.9486 2067438 IFLab1_003144 CCC(C(=O)NCc1ccc2n(C)c(C)cc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O21 compound treatment 0.341 0.0149 0.59 0.344 0.0156 0.33 0.6456 0.9613 2067439 IFLab1_003145 O=C(CCn1c(=O)sc2ccccc12)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O22 compound treatment 0.341 0.0149 0.59 0.345 0.0166 0.35 0.6604 0.9683 2067440 IFLab1_003146 Cc1cc2cc(CNC(=O)c3cc4ccccc4oc3=O)ccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O23 mock treatment 0.328 0.00194 0.08 0.335 0.00656 0.14 0.151 0.9613 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 O24 positive control 0.091 -0.235 -9.24 0.094 -0.234 -4.91 -10.0042 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P01 compound treatment 0.351 0.0249 0.98 0.372 0.0436 0.91 1.3379 0.9993 2067441 IFLab1_003147 CCCCC(=O)NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P02 compound treatment 0.323 -0.00306 -0.12 0.332 0.00356 0.07 -0.0324 -0.229 2067442 IFLab1_003148 CCN1CCN(CC1)C(C(C)NC(=O)c2ccco2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P03 compound treatment 0.375 0.0489 1.92 0.354 0.0256 0.53 1.7388 0.8707 2067443 IFLab1_003149 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCc2ccc3[nH]c4CCCCc4c3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P04 compound treatment 0.351 0.0249 0.98 0.345 0.0166 0.35 0.9384 0.9023 2067444 IFLab1_003150 CC(NC(=O)c1cccs1)C(N2CCN(Cc3ccccc3)CC2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P05 compound treatment 0.399 0.0729 2.87 0.401 0.0726 1.52 3.1015 0.9558 2067445 IFLab1_003151 CCS(=O)(=O)NCc1ccc2n(C)c(C)cc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P06 compound treatment 0.363 0.0369 1.45 0.37 0.0416 0.87 1.6419 0.9699 2067446 IFLab1_003152 CC(NS(=O)(=O)c1ccccc1)C(N2CCN(CC2)c3ccccc3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P07 compound treatment 0.375 0.0489 1.92 0.366 0.0376 0.79 1.9164 0.922 2067447 IFLab1_003153 Cn1c(SCC=C)nnc1c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P08 compound treatment 0.384 0.0579 2.28 0.371 0.0426 0.89 2.2406 0.916 2067448 IFLab1_003154 Cn1c(nc2ccccc12)C3CN(Cc4ccccc4)C(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P09 compound treatment 0.37 0.0439 1.73 0.374 0.0456 0.95 1.8957 0.9608 2067449 IFLab1_003155 CCOC(=O)C(CC)Sc1nnc(c2c[nH]c3ccccc23)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P10 compound treatment 0.376 0.0499 1.96 0.38 0.0516 1.08 2.1513 0.9603 2067450 IFLab1_003156 CSc1nnc(Cn2c(=O)sc3ccccc23)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P11 compound treatment 0.367 0.0409 1.61 0.364 0.0356 0.74 1.6644 0.9386 2067451 IFLab1_003157 CCC(Sc1nnc(c2c[nH]c3ccccc23)n1CC)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P12 compound treatment 0.373 0.0469 1.85 0.368 0.0396 0.83 1.8904 0.9346 2067452 IFLab1_003158 O=C(CN1C(=O)CC(Sc2ccccc12)c3ccccc3)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P13 compound treatment 0.385 0.0589 2.32 0.374 0.0456 0.95 2.3128 0.923 2067453 IFLab1_003159 NC(=O)CSc1nnc(c2c[nH]c3ccccc23)n1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P14 compound treatment 0.36 0.0339 1.33 0.369 0.0406 0.85 1.5437 0.9762 2067454 IFLab1_003160 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCOCC2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P15 compound treatment 0.357 0.0309 1.22 0.355 0.0266 0.56 1.2532 0.937 2067455 IFLab1_003161 CC(NC(=O)c1c(F)cccc1F)C(N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P16 compound treatment 0.359 0.0329 1.3 0.364 0.0356 0.74 1.442 0.9654 2067456 IFLab1_003162 CCOC(=O)c1c(C)c(C(=O)Nc2ccc(C)cc2)c(C)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P17 compound treatment 0.356 0.0299 1.18 0.361 0.0326 0.68 1.3142 0.9662 2067457 IFLab1_003163 COc1ccccc1C(=O)NC(C)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P18 compound treatment 0.358 0.0319 1.26 0.353 0.0246 0.51 1.2514 0.9223 2067458 IFLab1_003164 O=C(CSc1ncnc2ccccc12)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P19 compound treatment 0.361 0.0349 1.37 0.355 0.0266 0.56 1.3644 0.9207 2067459 IFLab1_003165 CC(NC(=O)c1ccc(cc1)N(C)C)C(N2CCN(C)CC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P20 compound treatment 0.367 0.0409 1.61 0.368 0.0396 0.83 1.7236 0.9522 2067460 IFLab1_003166 CCOC(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P21 compound treatment 0.361 0.0349 1.37 0.36 0.0316 0.66 1.4384 0.9437 2067461 IFLab1_003167 CCSc1nnc(NC(=O)CSC2=NCCS2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P22 compound treatment 0.347 0.0209 0.82 0.352 0.0236 0.49 0.9308 0.97 2067462 IFLab1_003168 CCOC(=O)C1CCN(CC1)C(=O)c2sc3nc(cn3c2C)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P23 mock treatment 0.344 0.0179 0.71 0.343 0.0146 0.3 0.7142 0.9296 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1420 P24 positive control 0.094 -0.232 -9.12 0.098 -0.23 -4.82 -9.8616 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A01 compound treatment 0.337 0.00981 0.39 0.341 0.0139 0.29 0.479 0.9905 2067463 IFLab1_003169 O=C(CSc1ncnc2ccccc12)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A02 compound treatment 0.326 -0.00119 -0.05 0.326 -0.00106 -0.02 -0.0487 -0.9424 1707401 IFLab1_003170 Cc1nc2c(ccc3nc(NC(=O)C4CC4)sc32)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A03 compound treatment 0.327 -1.88E-4 -0.01 0.337 0.00994 0.21 0.1418 0.6816 2067464 IFLab1_003171 Cc1ccc(C)c(CSc2ncnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A04 compound treatment 0.326 -0.00119 -0.05 0.323 -0.00406 -0.09 -0.0931 -0.9602 1243518 IFLab1_003172 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCNC(=O)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A05 compound treatment 0.357 0.0298 1.17 0.318 -0.00906 -0.19 0.6947 0.5851 2067465 IFLab1_003173 Fc1ccc(cc1)c2nnc3ccc(SCC(=O)OCc4ccccc4)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A06 compound treatment 0.349 0.0218 0.86 0.342 0.0149 0.31 0.8275 0.9065 2067466 IFLab1_003174 N#CC(=C(/C=C/c1ccccc1)C2CC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A07 compound treatment 0.331 0.00381 0.15 0.317 -0.0101 -0.21 -0.0429 -0.166 1486765 IFLab1_003175 CCOC(=O)c1csc(NC(=O)COc2ccc(Cl)cc2Cl)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A08 compound treatment 0.364 0.0368 1.45 0.38 0.0529 1.11 1.8068 0.9913 1453180 IFLab1_003176 Cc1ccc2nc(NCCO)nc(c3ccccc3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A09 compound treatment 0.324 -0.00319 -0.13 0.32 -0.00706 -0.15 -0.1931 -0.9966 1125483 IFLab1_003177 CC(C)c1cc(NS(=O)(=O)c2ccccc2)c(C)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A10 compound treatment 0.354 0.0268 1.05 0.317 -0.0101 -0.21 0.5965 0.5549 1290154 IFLab1_003178 O=C(N1CCN(CC1)c2ccccc2)C3(CC3)S(=O)(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A11 compound treatment 0.362 0.0348 1.37 0.378 0.0509 1.07 1.7216 0.9924 1449642 IFLab1_003179 COc1ccc(NC(=O)c2csc3CCCCc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A12 compound treatment 0.371 0.0438 1.72 0.369 0.0419 0.88 1.8386 0.951 2067467 IFLab1_003180 Cc1ccc(o1)c2csc(NC(=O)/C=C/c3ccccc3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A13 compound treatment 0.328 8.12E-4 0.03 0.332 0.00494 0.1 0.0956 0.8844 1682012 IFLab1_003181 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)N2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A14 compound treatment 0.351 0.0238 0.94 0.332 0.00494 0.1 0.7351 0.7804 1382951 IFLab1_003182 COC(=O)c1ccc(Oc2coc3cc(O)ccc3c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A15 compound treatment 0.335 0.00781 0.31 0.353 0.0259 0.54 0.601 0.9637 2067468 IFLab1_003183 Clc1cc(C(=O)Nc2ccc3OCOc3c2)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A16 compound treatment 0.326 -0.00119 -0.05 0.325 -0.00206 -0.04 -0.0635 -0.9992 1506201 IFLab1_003184 COc1cc(C)c2c(=O)c(Oc3ccccc3)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A17 compound treatment 0.323 -0.00419 -0.16 0.348 0.0209 0.44 0.1934 0.4132 1429516 IFLab1_003185 CC1CCCN(CC(O)COCc2ccc3OCOc3c2)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A18 compound treatment 0.35 0.0228 0.9 0.326 -0.00106 -0.02 0.6185 0.6894 2067469 IFLab1_003186 Fc1ccc(cc1)c2csc3nc[nH]c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A19 compound treatment 0.32 -0.00719 -0.28 0.32 -0.00706 -0.15 -0.3043 -0.9543 1692215 IFLab1_003187 OC(COc1ccc(Cl)cc1)CN2CCC(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A20 compound treatment 0.323 -0.00419 -0.16 0.338 0.0109 0.23 0.0454 0.1611 1726881 IFLab1_003188 C1Cc2sc3ncnc(N4CCCCC4)c3c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A21 compound treatment 0.34 0.0128 0.5 0.321 -0.00606 -0.13 0.2665 0.513 1983497 IFLab1_003189 Brc1ccccc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A22 compound treatment 0.314 -0.0132 -0.52 0.325 -0.00206 -0.04 -0.3972 -0.7633 1308511 IFLab1_003190 O=S(=O)(Nc1cccnc1)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A23 mock treatment 0.319 -0.00819 -0.32 0.319 -0.00806 -0.17 -0.3469 -0.9545 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 A24 positive control 0.078 -0.249 -9.8 0.081 -0.246 -5.15 -10.5689 -0.9549 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B01 compound treatment 0.339 0.0118 0.46 0.344 0.0169 0.35 0.579 0.9911 2067470 IFLab1_003191 COc1ccc2c(C)cc(SCc3c(C)noc3C)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B02 compound treatment 0.321 -0.00619 -0.24 0.332 0.00494 0.1 -0.099 -0.3744 2067471 IFLab1_003192 CC(=O)Nc1ccc(N/C=C(/C#N)\c2nc(cs2)c3ccc(Cl)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B03 compound treatment 0.322 -0.00519 -0.2 0.315 -0.0121 -0.25 -0.3227 -0.9944 2067472 IFLab1_003193 CCc1nc2sc3CCCc3c2c4nncn14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B04 compound treatment 0.388 0.0608 2.39 0.366 0.0389 0.81 2.2669 0.8974 2067473 IFLab1_003194 CCOC(=O)CCN1C(=O)/C(=C\c2cccs2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B05 compound treatment 0.322 -0.00519 -0.2 0.323 -0.00406 -0.09 -0.2043 -0.9247 1355776 IFLab1_003195 CC1CN(CC(C)O1)c2nc(C)nc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B06 compound treatment 0.335 0.00781 0.31 0.319 -0.00806 -0.17 0.0979 0.2794 1517771 IFLab1_003196 OC(=O)C1CCCN(C1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B07 compound treatment 0.333 0.00581 0.23 0.34 0.0129 0.27 0.353 0.9964 1371219 IFLab1_003197 COc1ccc(cc1OC)c2csc3ncn(n4c(C)ccc4C)c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B08 compound treatment 0.353 0.0258 1.01 0.348 0.0209 0.44 1.0275 0.9295 1238926 IFLab1_003198 O=C(Nc1ccc2ccccc2c1)C3CCCN(C3)S(=O)(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B09 compound treatment 0.312 -0.0152 -0.6 0.336 0.00894 0.19 -0.29 -0.4634 2067474 IFLab1_003199 CCSc1nnc(NC(=O)C(C)SC2=NCCS2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B10 compound treatment 0.34 0.0128 0.5 0.337 0.00994 0.21 0.5033 0.9234 1285934 IFLab1_003200 CC1(CC2CC(C)(C)C1)CN2C(=O)C3CCN(CC3)S(=O)(=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B11 compound treatment 0.38 0.0528 2.08 0.383 0.0559 1.17 2.296 0.9632 2067475 IFLab1_003201 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC(C)(C)C)C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B12 compound treatment 0.318 -0.00919 -0.36 0.316 -0.0111 -0.23 -0.4191 -0.9769 1414036 IFLab1_003202 OC(=O)CCC(=O)Nc1nc(cs1)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B13 compound treatment 0.329 0.00181 0.07 0.333 0.00594 0.12 0.1382 0.9652 1644254 IFLab1_003203 OC(=O)c1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B14 compound treatment 0.364 0.0368 1.45 0.357 0.0299 0.63 1.4664 0.9298 2067476 IFLab1_003204 Oc1ccccc1/C=N/c2oc(c3ccco3)c(c2C#N)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B15 compound treatment 0.317 -0.0102 -0.4 0.336 0.00894 0.19 -0.151 -0.3415 2067477 IFLab1_003205 Cc1nn(CO)c(C)c1Sc2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B16 compound treatment 0.327 -1.88E-4 -0.01 0.341 0.0139 0.29 0.201 0.689 1224211 IFLab1_003206 CCOC(=O)c1c(NC(=O)c2ccccc2C(=O)O)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B17 compound treatment 0.341 0.0138 0.54 0.323 -0.00406 -0.09 0.3239 0.5892 1405871 IFLab1_003207 Cc1[nH]nc(c1c2ccccc2C)c3ccc(O)c(C)c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B18 compound treatment 0.335 0.00781 0.31 0.333 0.00594 0.12 0.3051 0.9207 2067478 IFLab1_003208 Cc1nc(c(C)s1)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B19 compound treatment 0.339 0.0118 0.46 0.336 0.00894 0.19 0.4607 0.9201 1180360 IFLab1_003209 COc1ccc(c2n[nH]cc2c3ccccc3)c(O)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B20 compound treatment 0.408 0.0808 3.18 0.409 0.0819 1.71 3.4592 0.9581 2067479 IFLab1_003210 Cc1sc(/N=C/c2ccco2)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B21 compound treatment 0.345 0.0178 0.7 0.347 0.0199 0.42 0.7902 0.9694 2067480 IFLab1_003211 Cc1cccc(N/C=C(\C#N)/c2nc(cs2)c3ccc4OCOc4c3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B22 compound treatment 0.337 0.00981 0.39 0.337 0.00994 0.21 0.4199 0.9579 1468849 IFLab1_003212 COc1ccc2oc(=O)c(cc2c1)C(=O)n3ccnc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B23 mock treatment 0.329 0.00181 0.07 0.328 9.38E-4 0.02 0.0643 0.8694 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 B24 positive control 0.078 -0.249 -9.8 0.08 -0.247 -5.17 -10.5837 -0.9554 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C01 compound treatment 0.338 0.0108 0.43 0.338 0.0109 0.23 0.4625 0.9578 2067481 IFLab1_003213 COc1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C02 compound treatment 0.326 -0.00119 -0.05 0.321 -0.00606 -0.13 -0.1227 -0.9078 1357765 IFLab1_003214 Cc1nc2c(ccc3nc(NC(=O)c4ccco4)sc32)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C03 compound treatment 0.322 -0.00519 -0.2 0.327 -6.25E-5 0.0 -0.1451 -0.7116 2067482 IFLab1_003215 COC(=O)c1ccc(CSc2ncnc3ccccc23)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C04 compound treatment 0.344 0.0168 0.66 0.33 0.00294 0.06 0.5109 0.7695 1225861 IFLab1_003216 Clc1ccc(cc1)S(=O)(=O)N2CCNC(=O)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C05 compound treatment 0.32 -0.00719 -0.28 0.327 -6.25E-5 0.0 -0.2008 -0.7104 2067483 IFLab1_003217 CCCCC(Sc1ccc2nnc(c3ccc(F)cc3)n2n1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C06 compound treatment 0.337 0.00981 0.39 0.32 -0.00706 -0.15 0.1683 0.4074 2067484 IFLab1_003218 CCOC(=O)CSc1nc(cc(c1C#N)c2ccccc2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C07 compound treatment 0.359 0.0318 1.25 0.36 0.0329 0.69 1.3718 0.9606 2067485 IFLab1_003219 CSc1nc2ccc(NC(=O)/C=C/c3cccs3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C08 compound treatment 0.37 0.0428 1.68 0.367 0.0399 0.84 1.7812 0.9478 1289522 IFLab1_003220 OCCNC(=O)c1ccc(Nc2nc(c3ccccc3)c4cc(Cl)ccc4n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C09 compound treatment 0.356 0.0288 1.13 0.365 0.0379 0.79 1.3624 0.9849 1726978 IFLab1_003221 CCC(=O)Nc1ccc(cc1)c2csc(n2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C10 compound treatment 0.337 0.00981 0.39 0.346 0.0189 0.4 0.553 0.9999 1607111 IFLab1_003222 O=S(N1CCCCCC1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C11 compound treatment 0.336 0.00881 0.35 0.333 0.00594 0.12 0.3329 0.9043 1402860 IFLab1_003223 Clc1ccccc1NC(=O)c2csc3CCCCc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C12 compound treatment 0.34 0.0128 0.5 0.323 -0.00406 -0.09 0.2961 0.5796 2067486 IFLab1_003224 Clc1cc(C(=O)OCc2nc3ccccc3s2)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C13 compound treatment 0.352 0.0248 0.98 0.363 0.0359 0.75 1.2216 0.9917 1259546 IFLab1_003225 Clc1cc(C(=O)Nc2nc3ccccc3s2)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C14 compound treatment 0.336 0.00881 0.35 0.325 -0.00206 -0.04 0.2145 0.6143 1465254 IFLab1_003226 CCc1cc(c2n[nH]cc2Oc3ccccc3)c(O)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C15 compound treatment 0.337 0.00981 0.39 0.336 0.00894 0.19 0.4051 0.9447 1677596 IFLab1_003227 O=C(Nc1nc(cs1)c2csc(NC(=O)C3CC3)n2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C16 compound treatment 0.34 0.0128 0.5 0.336 0.00894 0.19 0.4885 0.909 2067487 IFLab1_003228 Oc1ccc(c2n[nH]cc2Oc3ccccc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C17 compound treatment 0.337 0.00981 0.39 0.334 0.00694 0.15 0.3755 0.9108 1188084 IFLab1_003229 CC1CCCC(C)N1CC(O)COCC2COc3ccccc3O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C18 compound treatment 0.339 0.0118 0.46 0.328 9.38E-4 0.02 0.3423 0.7363 2067488 IFLab1_003230 Cc1noc(C)c1CSc2ncnc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C19 compound treatment 0.329 0.00181 0.07 0.329 0.00194 0.04 0.0791 0.9643 1369316 IFLab1_003231 COc1cc(CC=C)ccc1OCC(O)CN2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C20 compound treatment 0.336 0.00881 0.35 0.338 0.0109 0.23 0.4068 0.9797 2067489 IFLab1_003232 Cc1cc2nnc(SCC(=O)O)n2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C21 compound treatment 0.336 0.00881 0.35 0.34 0.0129 0.27 0.4364 0.9926 2067490 IFLab1_003233 Fc1cccc(/C=C\2/N=C(OC2=O)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C22 compound treatment 0.324 -0.00319 -0.13 0.325 -0.00206 -0.04 -0.1191 -0.8988 2067491 IFLab1_003234 NC(=O)c1cnn(c1N)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C23 mock treatment 0.324 -0.00319 -0.13 0.325 -0.00206 -0.04 -0.1191 -0.8988 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 C24 positive control 0.08 -0.247 -9.72 0.08 -0.247 -5.17 -10.5281 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D01 compound treatment 0.348 0.0208 0.82 0.343 0.0159 0.33 0.8145 0.9217 2067492 IFLab1_003235 Cc1noc(C)c1CSc2nnnn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D02 compound treatment 0.358 0.0308 1.21 0.344 0.0169 0.35 1.1073 0.8772 2067493 IFLab1_003236 CCOc1ccc(cc1)c2csc(n2)/C(=C\Nc3ccc(NC(=O)C)cc3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D03 compound treatment 0.333 0.00581 0.23 0.331 0.00394 0.08 0.2199 0.905 2067494 IFLab1_003237 CCc1nc2sc3CCCc3c2c4nnc(C)n14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D04 compound treatment 0.34 0.0128 0.5 0.331 0.00394 0.08 0.4145 0.812 2067495 IFLab1_003238 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D05 compound treatment 0.361 0.0338 1.33 0.355 0.0279 0.58 1.3534 0.9319 2067496 IFLab1_003239 Cc1nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c3cnn(c4ccccc4)c3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D06 compound treatment 0.333 0.00581 0.23 0.334 0.00694 0.15 0.2643 0.976 1238050 IFLab1_003240 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCCC(C2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D07 compound treatment 0.342 0.0148 0.58 0.332 0.00494 0.1 0.4849 0.8198 1257742 IFLab1_003241 CCc1nnc(NC(=O)C(C)Sc2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D08 compound treatment 0.335 0.00781 0.31 0.344 0.0169 0.35 0.4678 0.9975 1358391 IFLab1_003242 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D09 compound treatment 0.354 0.0268 1.05 0.346 0.0189 0.4 1.0257 0.9107 1335988 IFLab1_003243 CCC(Sc1ccc(Cl)cc1)C(=O)Nc2nnc(C)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D10 compound treatment 0.333 0.00581 0.23 0.341 0.0139 0.29 0.3678 0.9927 2067497 IFLab1_003244 CCOC(=O)c1c(C)c(C)sc1NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D11 compound treatment 0.41 0.0828 3.26 0.407 0.0799 1.67 3.4852 0.9521 2067498 IFLab1_003245 OC(=O)c1ccc(/C=C/2\S\C(=N/c3ccc(O)cc3)\NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D12 compound treatment 0.334 0.00681 0.27 0.336 0.00894 0.19 0.3217 0.9846 1645660 IFLab1_003246 CCOC(=O)c1c(C)c(C)sc1NC(=O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D13 compound treatment 0.334 0.00681 0.27 0.339 0.0119 0.25 0.366 0.9994 1255590 IFLab1_003247 OC(=O)c1ccccc1N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D14 compound treatment 0.333 0.00581 0.23 0.337 0.00994 0.21 0.3086 0.9989 1593881 IFLab1_003248 COc1ccccc1NC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D15 compound treatment 0.33 0.00281 0.11 0.337 0.00994 0.21 0.2252 0.9563 1175935 IFLab1_003249 COc1ccc(C(=O)COc2ccccc2)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D16 compound treatment 0.33 0.00281 0.11 0.33 0.00294 0.06 0.1217 0.9616 1028611 IFLab1_003250 OC(=O)c1ccccc1C(=O)Nc2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D17 compound treatment 0.334 0.00681 0.27 0.34 0.0129 0.27 0.3808 1.0 1721182 IFLab1_003251 Cc1ccccc1c2c(C)oc3cc(O)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D18 compound treatment 0.332 0.00481 0.19 0.333 0.00594 0.12 0.2217 0.9792 1113514 IFLab1_003252 CCC(=O)Nc1ccc(C)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D19 compound treatment 0.334 0.00681 0.27 0.345 0.0179 0.38 0.4548 0.9863 1450543 IFLab1_003253 CCOc1ccc(c2nn(C)c(C)c2Oc3ccccc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D20 compound treatment 0.34 0.0128 0.5 0.337 0.00994 0.21 0.5033 0.9234 1448679 IFLab1_003254 CC(Sc1nc2ccccc2o1)C(=O)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D21 compound treatment 0.342 0.0148 0.58 0.346 0.0189 0.4 0.692 0.9824 2067499 IFLab1_003255 CCOc1ccc(cc1)c2csc(n2)/C(=C/Nc3ccccc3OC)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D22 compound treatment 0.329 0.00181 0.07 0.331 0.00394 0.08 0.1087 0.9974 1568669 IFLab1_003256 COc1ccccc1Nc2nc(cs2)c3cc4cccc(OC)c4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D23 mock treatment 0.322 -0.00519 -0.2 0.328 9.38E-4 0.02 -0.1304 -0.6362 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 D24 positive control 0.08 -0.247 -9.72 0.079 -0.248 -5.19 -10.5429 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E01 compound treatment 0.343 0.0158 0.62 0.336 0.00894 0.19 0.5719 0.8808 2067500 IFLab1_003257 O=C(CSc1ncnc2ccccc12)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E02 compound treatment 0.38 0.0528 2.08 0.381 0.0539 1.13 2.2664 0.959 1377062 IFLab1_003258 O=C(Nc1ccc(cc1)c2nc3ccccc3[nH]2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E03 compound treatment 0.322 -0.00519 -0.2 0.319 -0.00806 -0.17 -0.2635 -0.9956 2067501 IFLab1_003259 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E04 compound treatment 0.335 0.00781 0.31 0.316 -0.0111 -0.23 0.0535 0.1391 1595210 IFLab1_003260 COc1ccc(cc1)S(=O)(=O)N2CCNC(=O)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E05 compound treatment 0.331 0.00381 0.15 0.323 -0.00406 -0.09 0.0459 0.2662 2067502 IFLab1_003261 Fc1ccc(cc1)c2nnc3ccc(SCC(=O)c4ccccc4)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E06 compound treatment 0.367 0.0398 1.57 0.367 0.0399 0.84 1.6978 0.9568 1343158 IFLab1_003262 COc1ccc(cc1)c2cc(nc3sc(C(=O)N)c(N)c23)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E07 compound treatment 0.339 0.0118 0.46 0.323 -0.00406 -0.09 0.2683 0.5682 1713395 IFLab1_003263 CSc1nc2ccc(NC(=O)CN3C(=O)CCC3=O)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E08 compound treatment 0.342 0.0148 0.58 0.341 0.0139 0.29 0.6181 0.9489 1724848 IFLab1_003264 CN(C1CCS(=O)(=O)C1)S(=O)(=O)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E09 compound treatment 0.348 0.0208 0.82 0.346 0.0189 0.4 0.8588 0.9446 1536646 IFLab1_003265 COc1cccc(c1)C(=O)Nc2ccc(cc2)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E10 compound treatment 0.345 0.0178 0.7 0.341 0.0139 0.29 0.7015 0.9246 1545984 IFLab1_003266 CN1CCN(CC1)S(=O)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E11 compound treatment 0.341 0.0138 0.54 0.342 0.0149 0.31 0.605 0.9656 1370968 IFLab1_003267 Cc1ccc(CCC(=O)Nc2ccc(C)cc2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E12 compound treatment 0.35 0.0228 0.9 0.343 0.0159 0.33 0.8701 0.9092 1626673 IFLab1_003268 CCCc1ccc(OCC(=O)c2ccc(O)cc2O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E13 compound treatment 0.34 0.0128 0.5 0.339 0.0119 0.25 0.5329 0.9476 2067503 IFLab1_003269 Cc1ccc2n(C)c(=NC(=O)c3cc(Cl)sc3Cl)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E14 compound treatment 0.336 0.00881 0.35 0.341 0.0139 0.29 0.4512 0.9963 1259259 IFLab1_003270 COc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E15 compound treatment 0.416 0.0888 3.49 0.403 0.0759 1.59 3.5928 0.9365 2067504 IFLab1_003271 COc1ccc(c2csc(NC(=O)/C=C/c3cccs3)n2)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E16 compound treatment 0.361 0.0338 1.33 0.369 0.0419 0.88 1.5606 0.9797 2067505 IFLab1_003272 COC(=O)c1ccc(Oc2c(oc3cc(O)ccc3c2=O)C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E17 compound treatment 0.329 0.00181 0.07 0.331 0.00394 0.08 0.1087 0.9974 1145970 IFLab1_003273 CC(C)C1CCC(C)CC1OCC(O)CN2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E18 compound treatment 0.386 0.0588 2.31 0.393 0.0659 1.38 2.6108 0.9696 2067506 IFLab1_003274 OC(=O)c1c(NC(=O)/C=C/c2cccs2)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E19 compound treatment 0.329 0.00181 0.07 0.338 0.0109 0.23 0.2122 0.8853 1429811 IFLab1_003275 COc1ccc(COCC(O)CN2C(C)CCCC2C)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E20 compound treatment 0.336 0.00881 0.35 0.338 0.0109 0.23 0.4068 0.9797 2067507 IFLab1_003276 Cc1cc(C(=O)CSc2nnc3ccccn23)c(C)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E21 compound treatment 0.342 0.0148 0.58 0.348 0.0209 0.44 0.7216 0.9902 2067508 IFLab1_003277 COc1ccccc1/C=C/2\N=C(OC2=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E22 compound treatment 0.341 0.0138 0.54 0.289 -0.0381 -0.8 -0.1792 -0.1859 1551354 IFLab1_003278 Cc1ccc(cc1C)c2nn3nnnc3c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E23 mock treatment 0.323 -0.00419 -0.16 0.323 -0.00406 -0.09 -0.1765 -0.9527 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 E24 positive control 0.081 -0.246 -9.68 0.081 -0.246 -5.15 -10.4855 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F01 compound treatment 0.365 0.0378 1.49 0.375 0.0479 1.0 1.7606 0.9817 2067509 IFLab1_003279 COc1ccc(/C=C/C(=O)Nc2sc3CCCCc3c2C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F02 compound treatment 0.344 0.0168 0.66 0.333 0.00594 0.12 0.5553 0.8256 2067510 IFLab1_003280 COc1cccc(c1)c2csc(n2)/C(=C\Nc3ccc(NC(=O)C)cc3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F03 compound treatment 0.318 -0.00919 -0.36 0.315 -0.0121 -0.25 -0.4339 -0.9846 1278829 IFLab1_003281 C1CN(CCO1)c2ncnc3scc(c4ccccc4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F04 compound treatment 0.324 -0.00319 -0.13 0.32 -0.00706 -0.15 -0.1931 -0.9966 1284006 IFLab1_003282 COc1ccc(NC(=O)CCCC(=O)O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F05 compound treatment 0.324 -0.00319 -0.13 0.318 -0.00906 -0.19 -0.2227 -0.9798 1175385 IFLab1_003283 COc1cc(cc(OC)c1OC)c2nc3sc4CCCc4c3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F06 compound treatment 0.336 0.00881 0.35 0.328 9.38E-4 0.02 0.2589 0.7459 1353868 IFLab1_003284 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCCCC2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F07 compound treatment 0.358 0.0308 1.21 0.356 0.0289 0.61 1.2848 0.9486 2067511 IFLab1_003285 CC(Sc1nc2ccccc2s1)C(=O)Nc3nnc(s3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F08 compound treatment 0.342 0.0148 0.58 0.327 -6.25E-5 0.0 0.4109 0.7055 1615740 IFLab1_003286 Cc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F09 compound treatment 0.356 0.0288 1.13 0.375 0.0479 1.0 1.5104 0.9982 1263143 IFLab1_003287 CCC(Sc1ccccc1)C(=O)Nc2nnc(s2)c3ccc(OC)cc3OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F10 compound treatment 0.392 0.0648 2.55 0.374 0.0469 0.98 2.4965 0.9141 1419097 IFLab1_003288 CCC(=O)Nc1ccc(cc1)c2nc3ccc(C)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F11 compound treatment 0.326 -0.00119 -0.05 0.363 0.0359 0.75 0.4988 0.6619 2067512 IFLab1_003289 Oc1ccc(/N=C\2/NC(=O)/C(=C/c3ccc(Cl)cc3Cl)/S2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F12 compound treatment 0.364 0.0368 1.45 0.35 0.0229 0.48 1.3629 0.8937 2067513 IFLab1_003290 Cc1sc(/N=C/c2ccc(O)cc2)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F13 compound treatment 0.354 0.0268 1.05 0.357 0.0299 0.63 1.1884 0.9691 2067514 IFLab1_003291 Cc1nn(C(=O)c2ccco2)c(C)c1Sc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F14 compound treatment 0.34 0.0128 0.5 0.351 0.0239 0.5 0.7104 1.0 1179283 IFLab1_003292 COc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F15 compound treatment 0.344 0.0168 0.66 0.343 0.0159 0.33 0.7033 0.9498 1640181 IFLab1_003293 Cc1oc2cc(O)ccc2c(=O)c1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F16 compound treatment 0.349 0.0218 0.86 0.353 0.0259 0.54 0.9902 0.9756 1049198 IFLab1_003294 CCOC(=O)c1c(C)c(C)sc1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F17 compound treatment 0.332 0.00481 0.19 0.332 0.00494 0.1 0.2069 0.9595 2067515 IFLab1_003295 CCOc1ccc(c2n[nH]c(c2Oc3ccccc3)C(F)(F)F)c(O)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F18 compound treatment 0.339 0.0118 0.46 0.347 0.0199 0.42 0.6234 0.9986 1663501 IFLab1_003296 CC(C)CC(=O)Nc1ccc(cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F19 compound treatment 0.353 0.0258 1.01 0.348 0.0209 0.44 1.0275 0.9295 1195788 IFLab1_003297 COc1ccc(c2n[nH]c(C)c2c3ccccc3)c(O)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F20 compound treatment 0.333 0.00581 0.23 0.334 0.00694 0.15 0.2643 0.976 1355410 IFLab1_003298 Cc1c(Cl)cccc1NC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F21 compound treatment 0.344 0.0168 0.66 0.349 0.0219 0.46 0.792 0.9841 2067516 IFLab1_003299 COc1ccc(N/C=C(\C#N)/c2nc(cs2)c3ccc4OCOc4c3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F22 compound treatment 0.334 0.00681 0.27 0.342 0.0149 0.31 0.4104 0.997 1601988 IFLab1_003300 COc1cccc2cc(C(=O)NCCc3ccccc3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F23 mock treatment 0.328 8.12E-4 0.03 0.325 -0.00206 -0.04 -0.0079 -0.1477 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 F24 positive control 0.081 -0.246 -9.68 0.081 -0.246 -5.15 -10.4855 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G01 compound treatment 0.353 0.0258 1.01 0.334 0.00694 0.15 0.8203 0.8001 2067517 IFLab1_003301 Cc1csc(NC(=O)CSc2ncnc3ccccc23)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G02 compound treatment 0.315 -0.0122 -0.48 0.324 -0.00306 -0.06 -0.3842 -0.7946 1254381 IFLab1_003302 CCC(=O)Nc1ccc(cc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G03 compound treatment 0.315 -0.0122 -0.48 0.313 -0.0141 -0.29 -0.5469 -0.9726 2067518 IFLab1_003303 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G04 compound treatment 0.326 -0.00119 -0.05 0.315 -0.0121 -0.25 -0.2115 -0.8239 1606394 IFLab1_003304 O=C1CCN(CCN1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G05 compound treatment 0.317 -0.0102 -0.4 0.33 0.00294 0.06 -0.2398 -0.5917 2067519 IFLab1_003305 CCOc1ccc(cc1)c2nnc3ccc(SC)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G06 compound treatment 0.324 -0.00319 -0.13 0.352 0.0249 0.52 0.2804 0.5224 1623658 IFLab1_003306 Nc1c(sc2nc(cc(c3ccc(Cl)cc3)c12)C4CC4)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G07 compound treatment 0.341 0.0138 0.54 0.36 0.0329 0.69 0.8714 0.993 1470386 IFLab1_003307 O=C(OCc1nc2ccccc2s1)c3cccc(c3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G08 compound treatment 0.326 -0.00119 -0.05 0.33 0.00294 0.06 0.0105 0.1354 1159893 IFLab1_003308 CN1CCN(CC1)S(=O)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G09 compound treatment 0.343 0.0158 0.62 0.378 0.0509 1.07 1.1933 0.9671 1418753 IFLab1_003309 OC(=O)CCC(=O)Nc1ccc(cc1)c2csc(n2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G10 compound treatment 0.333 0.00581 0.23 0.382 0.0549 1.15 0.9745 0.8314 2067520 IFLab1_003310 S(c1c(nc2ncccn12)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G11 compound treatment 0.335 0.00781 0.31 0.369 0.0419 0.88 0.8378 0.901 1214346 IFLab1_003311 CN(C)c1ccc(cc1)P(=O)(OCc2ccccc2)C(O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G12 compound treatment 0.356 0.0288 1.13 0.379 0.0519 1.09 1.5696 0.9998 1208321 IFLab1_003312 Cc1c(O)ccc2c(=O)c(Oc3ccccc3)coc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G13 compound treatment 0.341 0.0138 0.54 0.348 0.0209 0.44 0.6938 0.9943 1466716 IFLab1_003313 CCOC(=O)Cc1csc(NC(=O)c2cc(Cl)sc2Cl)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G14 compound treatment 0.334 0.00681 0.27 0.373 0.0459 0.96 0.8691 0.871 2067521 IFLab1_003314 Cc1[nH]nc(c1Oc2ccccc2)c3ccc(O)cc3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G15 compound treatment 0.341 0.0138 0.54 0.389 0.0619 1.3 1.3005 0.9254 1675481 IFLab1_003315 COc1ccc(cc1)C(=O)Nc2nc(cs2)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G16 compound treatment 0.308 -0.0192 -0.75 0.345 0.0179 0.38 -0.268 -0.3181 1477422 IFLab1_003316 CCCOc1ccc(c2n[nH]cc2Oc3ccccc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G17 compound treatment 0.334 0.00681 0.27 0.358 0.0309 0.65 0.6472 0.9237 1171118 IFLab1_003317 OC(COc1ccc2OCOc2c1)CN3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G18 compound treatment 0.334 0.00681 0.27 0.371 0.0439 0.92 0.8395 0.8767 1523521 IFLab1_003318 C1CN(CCO1)c2nnc(N3CCOCC3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G19 compound treatment 0.336 0.00881 0.35 0.344 0.0169 0.35 0.4956 0.9999 1119823 IFLab1_003319 Cc1cccc(C)c1OCC(O)CN2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G20 compound treatment 0.331 0.00381 0.15 0.332 0.00494 0.1 0.1791 0.9835 1366277 IFLab1_003320 CN1CCN(CC1)c2nnc(c3ccccc3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G21 compound treatment 0.337 0.00981 0.39 0.324 -0.00306 -0.06 0.2275 0.5817 1446410 IFLab1_003321 Clc1ccc2n(COC(=O)NC3CCCCC3)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G22 compound treatment 0.327 -1.88E-4 -0.01 0.329 0.00194 0.04 0.0235 0.5692 2067522 IFLab1_003322 Cc1ccc(cc1)c2nn3cnnc3c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G23 mock treatment 0.321 -0.00619 -0.24 0.324 -0.00306 -0.06 -0.2173 -0.8639 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 G24 positive control 0.081 -0.246 -9.68 0.081 -0.246 -5.15 -10.4855 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H01 compound treatment 0.364 0.0368 1.45 0.348 0.0209 0.44 1.3333 0.8816 2067523 IFLab1_003323 CC(C)(C)c1ccc(NC(=O)CSc2nnnn2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H02 compound treatment 0.322 -0.00519 -0.2 0.331 0.00394 0.08 -0.086 -0.3908 2067524 IFLab1_003324 COc1ccc(Cl)cc1N/C=C(\C#N)/c2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H03 compound treatment 0.347 0.0198 0.78 0.334 0.00694 0.15 0.6535 0.8247 2067525 IFLab1_003325 S=c1[nH]cnc2scc(c3ccccc3)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H04 compound treatment 0.337 0.00981 0.39 0.332 0.00494 0.1 0.3459 0.866 1669631 IFLab1_003326 OC(=O)CCCC(=O)Nc1cccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H05 compound treatment 0.334 0.00681 0.27 0.334 0.00694 0.15 0.2921 0.9586 2067526 IFLab1_003327 CN(C)c1ccc(/C=C\2/N=C(OC2=O)c3cccs3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H06 compound treatment 0.345 0.0178 0.7 0.329 0.00194 0.04 0.5239 0.7468 2067527 IFLab1_003328 FC(F)(F)C1CCCN(C1)S(=O)(=O)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H07 compound treatment 0.343 0.0158 0.62 0.358 0.0309 0.65 0.8974 0.9998 1561214 IFLab1_003329 CC(SC1=NCCS1)C(=O)Nc2nnc(s2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H08 compound treatment 0.338 0.0108 0.43 0.328 9.38E-4 0.02 0.3145 0.739 1250459 IFLab1_003330 CN(C(=O)C1CCCN(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H09 compound treatment 0.353 0.0258 1.01 0.344 0.0169 0.35 0.9683 0.9007 1656241 IFLab1_003331 CCSc1nnc(NC(=O)C(CC)Sc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H10 compound treatment 0.345 0.0178 0.7 0.336 0.00894 0.19 0.6275 0.8656 1720041 IFLab1_003332 OC(=O)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H11 compound treatment 0.403 0.0758 2.98 0.396 0.0689 1.44 3.1278 0.9445 2067528 IFLab1_003333 Cc1ccc(/C=C\2/S/C(=N/c3ccc(O)cc3)/NC2=O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H12 compound treatment 0.316 -0.0112 -0.44 0.345 0.0179 0.38 -0.0456 -0.0789 1520208 IFLab1_003334 CC(=O)Nc1ccc(OC(=O)c2cc3ccccc3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H13 compound treatment 0.343 0.0158 0.62 0.343 0.0159 0.33 0.6754 0.9574 1435135 IFLab1_003335 Cc1nn(C(=O)c2cccnc2)c(C)c1Sc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H14 compound treatment 0.344 0.0168 0.66 0.343 0.0159 0.33 0.7033 0.9498 1129935 IFLab1_003336 O=C(Oc1ccccc1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H15 compound treatment 0.338 0.0108 0.43 0.335 0.00794 0.17 0.4181 0.916 1051974 IFLab1_003337 COc1ccc(cc1)c2c(C)oc3cc(OC(=O)C)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H16 compound treatment 0.339 0.0118 0.46 0.338 0.0109 0.23 0.4903 0.9468 2067529 IFLab1_003338 N(c1nc(cs1)c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H17 compound treatment 0.353 0.0258 1.01 0.355 0.0279 0.58 1.131 0.9657 2067530 IFLab1_003339 Cc1c(O)ccc2c(=O)c(c3ccc(F)cc3)c(oc12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H18 compound treatment 0.323 -0.00419 -0.16 0.337 0.00994 0.21 0.0306 0.1155 2067531 IFLab1_003340 Cc1nc(cs1)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H19 compound treatment 0.334 0.00681 0.27 0.337 0.00994 0.21 0.3364 0.9922 1187065 IFLab1_003341 COc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H20 compound treatment 0.337 0.00981 0.39 0.329 0.00194 0.04 0.3015 0.7771 1626157 IFLab1_003342 CC1CCCC(C)N1C(=O)c2ccccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H21 compound treatment 0.335 0.00781 0.31 0.335 0.00794 0.17 0.3347 0.9583 2067532 IFLab1_003343 Fc1ccc(cc1)c2csc(n2)/C(=C\Nc3cccc(Cl)c3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H22 compound treatment 0.406 0.0788 3.1 0.407 0.0799 1.67 3.374 0.9581 1212413 IFLab1_003344 Clc1cc(Cl)c2oc(=O)c(cc2c1)C(=O)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H23 mock treatment 0.323 -0.00419 -0.16 0.324 -0.00306 -0.06 -0.1617 -0.9154 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 H24 positive control 0.083 -0.244 -9.6 0.082 -0.245 -5.13 -10.4151 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I01 compound treatment 0.342 0.0148 0.58 0.349 0.0219 0.46 0.7364 0.9931 2067533 IFLab1_003345 CCOC(=O)c1c(NC(=O)CSc2ncnc3ccccc23)sc4CCCc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I02 compound treatment 0.416 0.0888 3.49 0.425 0.0979 2.05 3.9184 0.9678 2067534 IFLab1_003346 O=C(Nc1ccc(cc1)c2nc3ccccc3[nH]2)/C=C/c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I03 compound treatment 0.336 0.00881 0.35 0.334 0.00694 0.15 0.3477 0.9254 2067535 IFLab1_003347 NC(=O)CSc1ccc2nnc(c3ccccc3)n2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I04 compound treatment 0.332 0.00481 0.19 0.33 0.00294 0.06 0.1773 0.891 1327413 IFLab1_003348 O=S(=O)(N1CCN(CC1)S(=O)(=O)c2cccs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I05 compound treatment 0.335 0.00781 0.31 0.365 0.0379 0.79 0.7786 0.9146 2067536 IFLab1_003349 CCOc1ccc(cc1)c2nnc3ccc(SCC)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I06 compound treatment 0.341 0.0138 0.54 0.335 0.00794 0.17 0.5015 0.883 2067537 IFLab1_003350 OC(=O)CSc1nc(cc(c1C#N)c2ccccc2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I07 compound treatment 0.352 0.0248 0.98 0.35 0.0229 0.48 1.0292 0.9466 1060520 IFLab1_003351 COc1ccc(cc1)C2=CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I08 compound treatment 0.342 0.0148 0.58 0.35 0.0229 0.48 0.7512 0.9954 1502026 IFLab1_003352 Cc1ccc(cc1)N(Cc2ccco2)C(=O)CNS(=O)(=O)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I09 compound treatment 0.345 0.0178 0.7 0.338 0.0109 0.23 0.6571 0.8918 2067538 IFLab1_003353 CC(C)OC(=O)c1cc2ccccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I10 compound treatment 0.344 0.0168 0.66 0.338 0.0109 0.23 0.6293 0.8995 2067539 IFLab1_003354 CC1Cc2ccccc2N1C(=O)COc3c(F)c(F)c(F)c(F)c3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I11 compound treatment 0.35 0.0228 0.9 0.353 0.0259 0.54 1.018 0.9711 1698498 IFLab1_003355 CN(C)c1ccc(cc1)P(=O)(OC2CCCCC2)C(O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I12 compound treatment 0.342 0.0148 0.58 0.334 0.00694 0.15 0.5145 0.8571 1383363 IFLab1_003356 CC(=O)Oc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I13 compound treatment 0.345 0.0178 0.7 0.346 0.0189 0.4 0.7754 0.9636 1142618 IFLab1_003357 Clc1cc(C(=O)Nc2nccs2)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I14 compound treatment 0.343 0.0158 0.62 0.346 0.0189 0.4 0.7198 0.9763 1346302 IFLab1_003358 CCc1cc(c2n[nH]cc2Oc3ccccc3)c(O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I15 compound treatment 0.364 0.0368 1.45 0.36 0.0329 0.69 1.5108 0.9424 1652338 IFLab1_003359 O=C(Nc1nc(cs1)c2ccncc2)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I16 compound treatment 0.378 0.0508 2.0 0.371 0.0439 0.92 2.0628 0.938 1645418 IFLab1_003360 Oc1ccc(cc1)c2nc(c3ccccc3)c4ccccn24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I17 compound treatment 0.345 0.0178 0.7 0.337 0.00994 0.21 0.6423 0.8791 1406699 IFLab1_003361 CCC1CCCCN1CC(O)COc2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I18 compound treatment 0.341 0.0138 0.54 0.335 0.00794 0.17 0.5015 0.883 1146596 IFLab1_003362 CN1CCN(CC1)c2ncnc3scc(c4ccc(F)cc4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I19 compound treatment 0.34 0.0128 0.5 0.334 0.00694 0.15 0.4589 0.8753 2067540 IFLab1_003363 CN1CCN(CC1)C(=O)CN2C(=O)S/C(=C\c3ccccc3F)/C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I20 compound treatment 0.332 0.00481 0.19 0.337 0.00994 0.21 0.2808 0.9989 2067541 IFLab1_003364 COC(=O)c1cc(cc(c1)n2c(C)ccc2C)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I21 compound treatment 0.336 0.00881 0.35 0.331 0.00394 0.08 0.3033 0.8515 2067542 IFLab1_003365 Fc1cccc(Cl)c1C2SCC(=O)N2c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I22 compound treatment 0.298 -0.0292 -1.15 0.337 0.00994 0.21 -0.6644 -0.5697 2067543 IFLab1_003366 COC(=O)/C(=C\c1cccnc1)/NC(=O)c2ccc(OCc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I23 mock treatment 0.335 0.00781 0.31 0.333 0.00594 0.12 0.3051 0.9207 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 I24 positive control 0.084 -0.243 -9.56 0.082 -0.245 -5.13 -10.3873 -0.9574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J01 compound treatment 0.337 0.00981 0.39 0.327 -6.25E-5 0.0 0.2719 0.7047 1166892 IFLab1_003367 CCOC(=O)c1c(NC(=O)CCN2CCC(C)CC2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J02 compound treatment 0.326 -0.00119 -0.05 0.32 -0.00706 -0.15 -0.1375 -0.8873 2067544 IFLab1_003368 N#C/C(=C/Nc1cccc2ccccc12)/c3nc(cs3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J03 compound treatment 0.316 -0.0112 -0.44 0.323 -0.00406 -0.09 -0.3711 -0.8284 2067545 IFLab1_003369 CC(=O)Oc1cc2sc(C)nc2c3sccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J04 compound treatment 0.33 0.00281 0.11 0.329 0.00194 0.04 0.1069 0.9073 2067546 IFLab1_003370 Cc1cccc(NC(=O)CCCOc2ccc(Cl)cc2Cl)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J05 compound treatment 0.345 0.0178 0.7 0.349 0.0219 0.46 0.8198 0.979 2067547 IFLab1_003371 N#CCSc1nnc(c2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J06 compound treatment 0.327 -1.88E-4 -0.01 0.318 -0.00906 -0.19 -0.1393 -0.734 2067548 IFLab1_003372 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J07 compound treatment 0.388 0.0608 2.39 0.384 0.0569 1.19 2.5332 0.9483 1356576 IFLab1_003373 CC(Sc1nc2ccccc2[nH]1)C(=O)Nc3nnc(s3)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J08 compound treatment 0.342 0.0148 0.58 0.342 0.0149 0.31 0.6328 0.9574 1361432 IFLab1_003374 O=C(C1CCN(CC1)S(=O)(=O)c2cccs2)N3CCc4ccccc4C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J09 compound treatment 0.215 -0.112 -4.41 0.228 -0.0991 -2.07 -4.5849 -0.9407 2067549 IFLab1_003375 Cc1ccc(cc1)C(=O)NCS(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J10 compound treatment 0.335 0.00781 0.31 0.344 0.0169 0.35 0.4678 0.9975 1627846 IFLab1_003376 CCOC(=O)c1c(NC(=O)CCCC(=O)O)scc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J11 compound treatment 0.362 0.0348 1.37 0.366 0.0389 0.81 1.544 0.9693 2067550 IFLab1_003377 CN1C(=O)/C(=C\2/S/C(=N\c3ccc(C)c(C)c3)/NC2=O)/c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J12 compound treatment 0.332 0.00481 0.19 0.343 0.0159 0.33 0.3696 0.9639 1648362 IFLab1_003378 Brc1ccc(cc1)C(=O)COC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J13 compound treatment 0.339 0.0118 0.46 0.357 0.0299 0.63 0.7714 0.9891 2067551 IFLab1_003379 Cc1ccc(SC(C(=O)c2ccccc2)C(=O)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J14 compound treatment 0.334 0.00681 0.27 0.343 0.0159 0.33 0.4252 0.9941 1161503 IFLab1_003380 COc1ccc(OC(=O)c2cc3ccccc3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J15 compound treatment 0.342 0.0148 0.58 0.335 0.00794 0.17 0.5293 0.8739 1370114 IFLab1_003381 COc1ccc(cc1)c2c(C)oc3cc(O)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J16 compound treatment 0.34 0.0128 0.5 0.344 0.0169 0.35 0.6068 0.9852 1075844 IFLab1_003382 CCc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J17 compound treatment 0.347 0.0198 0.78 0.34 0.0129 0.27 0.7423 0.9001 1151392 IFLab1_003383 CCOc1ccc2c(=O)c(coc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J18 compound treatment 0.34 0.0128 0.5 0.346 0.0189 0.4 0.6364 0.9929 2067552 IFLab1_003384 CCOC(=O)c1c(NC(=O)/C=C\C(=O)O)sc(C)c1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J19 compound treatment 0.368 0.0408 1.6 0.361 0.0339 0.71 1.6368 0.9328 1293115 IFLab1_003385 Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J20 compound treatment 0.344 0.0168 0.66 0.338 0.0109 0.23 0.6293 0.8995 1625895 IFLab1_003386 CCN(C(=O)c1cc2ccccc2oc1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J21 compound treatment 0.337 0.00981 0.39 0.339 0.0119 0.25 0.4494 0.9779 2067553 IFLab1_003387 Clc1cccc(N/C=C(\C#N)/c2nc(cs2)c3ccc4OCOc4c3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J22 compound treatment 0.355 0.0278 1.09 0.356 0.0289 0.61 1.2014 0.9611 1182925 IFLab1_003388 CC(NC(=O)C(c1ccccc1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J23 mock treatment 0.327 -1.88E-4 -0.01 0.323 -0.00406 -0.09 -0.0653 -0.7656 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 J24 positive control 0.084 -0.243 -9.56 0.083 -0.244 -5.11 -10.3725 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K01 compound treatment 0.34 0.0128 0.5 0.336 0.00894 0.19 0.4885 0.909 1039953 IFLab1_003389 C(Sc1ncnc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K02 compound treatment 0.366 0.0388 1.53 0.385 0.0579 1.21 1.9364 0.9935 1175995 IFLab1_003390 COC(=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K03 compound treatment 0.321 -0.00619 -0.24 0.322 -0.00506 -0.11 -0.2469 -0.9306 2067554 IFLab1_003391 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K04 compound treatment 0.335 0.00781 0.31 0.33 0.00294 0.06 0.2607 0.8321 1382032 IFLab1_003392 CCSc1nc(cc(c2ccco2)c1C#N)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K05 compound treatment 0.345 0.0178 0.7 0.358 0.0309 0.65 0.953 0.9992 2067555 IFLab1_003393 COc1ccc(cc1OC)c2nnc3ccc(SCc4ccccc4F)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K06 compound treatment 0.398 0.0708 2.78 0.401 0.0739 1.55 3.0628 0.9616 1640446 IFLab1_003394 NC(=O)CSc1nc(cc(c2cccs2)c1C#N)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K07 compound treatment 0.336 0.00881 0.35 0.327 -6.25E-5 0.0 0.2441 0.7044 1032557 IFLab1_003395 C=CC(=O)N1CCN(CC1)C(=O)C=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K08 compound treatment 0.337 0.00981 0.39 0.337 0.00994 0.21 0.4199 0.9579 1408889 IFLab1_003396 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccs2)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K09 compound treatment 0.338 0.0108 0.43 0.342 0.0149 0.31 0.5216 0.9886 2067556 IFLab1_003397 Cc1ccc(/C=C/C(=O)Nc2ccccc2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K10 compound treatment 0.344 0.0168 0.66 0.343 0.0159 0.33 0.7033 0.9498 1307317 IFLab1_003398 O=C(N(Cc1ccccc1)c2ccccn2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K11 compound treatment 0.34 0.0128 0.5 0.343 0.0159 0.33 0.592 0.9799 1485325 IFLab1_003399 CC(C)C(O)P(=O)(OCc1ccccc1)c2ccc(cc2)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K12 compound treatment 0.374 0.0468 1.84 0.389 0.0619 1.3 2.218 0.9853 2067557 IFLab1_003400 Cc1c(O)ccc2c(=O)c(Oc3ccccc3)c(oc12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K13 compound treatment 0.343 0.0158 0.62 0.346 0.0189 0.4 0.7198 0.9763 1298394 IFLab1_003401 CCOC(=O)c1ccc(NC(=O)c2cc(Cl)sc2Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K14 compound treatment 0.339 0.0118 0.46 0.333 0.00594 0.12 0.4163 0.8658 1488365 IFLab1_003402 CCOc1cc(O)c(cc1CC)c2n[nH]cc2Oc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K15 compound treatment 0.345 0.0178 0.7 0.342 0.0149 0.31 0.7163 0.9339 1558600 IFLab1_003403 COC(=O)c1ccc(cc1)C(=O)Nc2nc(cs2)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K16 compound treatment 0.349 0.0218 0.86 0.348 0.0209 0.44 0.9162 0.9514 1220961 IFLab1_003404 OCc1cc(=O)c(O)c(o1)C(Nc2nccs2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K17 compound treatment 0.342 0.0148 0.58 0.342 0.0149 0.31 0.6328 0.9574 2067558 IFLab1_003405 OC(COCCC1(CC2CC3CC(C2)C1)C3)CN4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K18 compound treatment 0.328 8.12E-4 0.03 0.34 0.0129 0.27 0.214 0.7851 1074365 IFLab1_003406 CCOC(=O)c1c(N)sc2CCCCCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K19 compound treatment 0.345 0.0178 0.7 0.344 0.0169 0.35 0.7458 0.9502 2067559 IFLab1_003407 Brc1ccc2cc(OC(=O)c3ccncc3)ccc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K20 compound treatment 0.32 -0.00719 -0.28 0.326 -0.00106 -0.02 -0.2155 -0.7604 2067560 IFLab1_003408 FC(F)(F)c1ccc(Cl)c(NC(=O)CCSc2nnnn2c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K21 compound treatment 0.338 0.0108 0.43 0.339 0.0119 0.25 0.4772 0.9679 2067561 IFLab1_003409 CC(=O)Nc1ccc(cc1)N2C(SCC2=O)c3c(F)cccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K22 compound treatment 0.343 0.0158 0.62 0.344 0.0169 0.35 0.6902 0.9645 2067562 IFLab1_003410 C(Sc1nnc2ccccn12)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K23 mock treatment 0.323 -0.00419 -0.16 0.325 -0.00206 -0.04 -0.1469 -0.8633 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 K24 positive control 0.084 -0.243 -9.56 0.084 -0.243 -5.09 -10.3577 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L01 compound treatment 0.337 0.00981 0.39 0.334 0.00694 0.15 0.3755 0.9108 1258224 IFLab1_003411 COc1ccc(C=c2sc3nc4ccccc4n3c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L02 compound treatment 0.318 -0.00919 -0.36 0.318 -0.00906 -0.19 -0.3895 -0.9548 2067563 IFLab1_003412 CCOc1ccc(cc1)c2csc(n2)/C(=C/Nc3ccc4OCOc4c3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L03 compound treatment 0.32 -0.00719 -0.28 0.323 -0.00406 -0.09 -0.2599 -0.8808 1239454 IFLab1_003413 Cc1ccc(C)n1n2cnc3sc4CCCc4c3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L04 compound treatment 0.324 -0.00319 -0.13 0.317 -0.0101 -0.21 -0.2375 -0.9693 1612805 IFLab1_003414 CCc1cc2c(=O)c(coc2cc1OC(C)C(=O)O)c3nc(C)cs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L05 compound treatment 0.325 -0.00219 -0.09 0.316 -0.0111 -0.23 -0.2245 -0.9091 1442760 IFLab1_003415 Fc1ccc(NC(=O)CCSc2nnc3ccccn23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L06 compound treatment 0.343 0.0158 0.62 0.34 0.0129 0.27 0.6311 0.9306 1983592 IFLab1_003416 O=S(=O)(c1cccs1)n2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L07 compound treatment 0.336 0.00881 0.35 0.344 0.0169 0.35 0.4956 0.9999 1554770 IFLab1_003417 CC(SC1=NCCS1)C(=O)Nc2nnc(s2)c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L08 compound treatment 0.326 -0.00119 -0.05 0.33 0.00294 0.06 0.0105 0.1354 1455385 IFLab1_003418 O=C(NCc1ccccc1)C2CCN(CC2)S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L09 compound treatment 0.355 0.0278 1.09 0.353 0.0259 0.54 1.157 0.9478 2067564 IFLab1_003419 CCOc1ccc(/C=C/2\SC(=S)N(CC(=O)N3CCCc4ccccc34)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L10 compound treatment 0.362 0.0348 1.37 0.35 0.0229 0.48 1.3073 0.9013 1587902 IFLab1_003420 CCN(CC)c1ccc(cc1)C(=O)OCC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L11 compound treatment 0.331 0.00381 0.15 0.331 0.00394 0.08 0.1643 0.9603 2067565 IFLab1_003421 Cc1ccc(NC(=O)CCCN2C(=O)/C(=C\c3ccc4OCOc4c3)/SC2=S)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L12 compound treatment 0.346 0.0188 0.74 0.341 0.0139 0.29 0.7293 0.9172 1160289 IFLab1_003422 CCOC(=O)c1cc2cccc(CC=C)c2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L13 compound treatment 0.347 0.0198 0.78 0.349 0.0219 0.46 0.8754 0.9682 2067566 IFLab1_003423 COc1ccc(cc1)S(=O)(=O)Nc2nc(cs2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L14 compound treatment 0.342 0.0148 0.58 0.336 0.00894 0.19 0.5441 0.8894 1597206 IFLab1_003424 NC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L15 compound treatment 0.339 0.0118 0.46 0.338 0.0109 0.23 0.4903 0.9468 1218304 IFLab1_003425 COc1ccc(cc1)c2c(C)oc3cc(OC)ccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L16 compound treatment 0.341 0.0138 0.54 0.338 0.0109 0.23 0.5459 0.9262 1075853 IFLab1_003426 OC(=O)c1ccccc1C(=O)Nc2ccccc2F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L17 compound treatment 0.341 0.0138 0.54 0.349 0.0219 0.46 0.7086 0.9965 2067567 IFLab1_003427 COc1ccc(cc1)c2c(n[nH]c2C(F)(F)F)c3ccc(O)cc3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L18 compound treatment 0.341 0.0138 0.54 0.336 0.00894 0.19 0.5163 0.8988 1709284 IFLab1_003428 CCOc1ccccc1NC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L19 compound treatment 0.345 0.0178 0.7 0.349 0.0219 0.46 0.8198 0.979 1176804 IFLab1_003429 CC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L20 compound treatment 0.342 0.0148 0.58 0.325 -0.00206 -0.04 0.3813 0.6529 1620579 IFLab1_003430 C=CCc1cccc2cc(C(=O)NCCC3=CCCCC3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L21 compound treatment 0.337 0.00981 0.39 0.344 0.0169 0.35 0.5234 0.9991 2067568 IFLab1_003431 Brc1ccc(N/C=C(\C#N)/c2nc(cs2)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L22 compound treatment 0.396 0.0688 2.71 0.393 0.0659 1.38 2.8888 0.9512 2067569 IFLab1_003432 Oc1c(Cl)cc(Cl)cc1/C=N/c2nc3CCCCc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L23 mock treatment 0.33 0.00281 0.11 0.33 0.00294 0.06 0.1217 0.9616 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 L24 positive control 0.086 -0.241 -9.48 0.085 -0.242 -5.07 -10.2873 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M01 compound treatment 0.326 -0.00119 -0.05 0.324 -0.00306 -0.06 -0.0783 -0.9879 2067570 IFLab1_003433 Fc1ccc(CSc2ncnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M02 compound treatment 0.328 8.12E-4 0.03 0.33 0.00294 0.06 0.0661 0.9535 1329441 IFLab1_003434 CCC(=O)Nc1cccc(c1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M03 compound treatment 0.347 0.0198 0.78 0.332 0.00494 0.1 0.6239 0.7939 2067571 IFLab1_003435 Cc1cc(C)c(NC(=O)CSc2ccc3nnc(c4ccccc4)n3n2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M04 compound treatment 0.367 0.0398 1.57 0.368 0.0409 0.86 1.7126 0.9598 1129291 IFLab1_003436 NC(=O)c1sc2nc(cc(c3cccs3)c2c1N)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M05 compound treatment 0.351 0.0238 0.94 0.346 0.0189 0.4 0.9423 0.9268 1277302 IFLab1_003437 CC1(C)CC(=O)c2sc(NC(=O)CCSc3ccccc3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M06 compound treatment 0.324 -0.00319 -0.13 0.323 -0.00406 -0.09 -0.1487 -0.9821 1526878 IFLab1_003438 C1CCN(C1)c2nc(c3ccccc3)c4ccccc4n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M07 compound treatment 0.356 0.0288 1.13 0.366 0.0389 0.81 1.3772 0.9869 2067572 IFLab1_003439 CC(=Cc1ccc(O)cc1)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M08 compound treatment 0.339 0.0118 0.46 0.341 0.0139 0.29 0.5346 0.9749 1492730 IFLab1_003440 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2(CC2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M09 compound treatment 0.34 0.0128 0.5 0.338 0.0109 0.23 0.5181 0.9363 1377193 IFLab1_003441 Cc1ccccc1NC(=O)c2csc3CCCCc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M10 compound treatment 0.351 0.0238 0.94 0.35 0.0229 0.48 1.0014 0.9518 1278533 IFLab1_003442 Cc1nn(C(=O)CNS(=O)(=O)c2ccccc2)c(C)c1Sc3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M11 compound treatment 0.347 0.0198 0.78 0.344 0.0169 0.35 0.8015 0.9365 1274575 IFLab1_003443 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M12 compound treatment 0.368 0.0408 1.6 0.371 0.0439 0.92 1.7848 0.9651 2067573 IFLab1_003444 CCc1cc2c(=O)c(Oc3ccccc3)c(oc2cc1O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M13 compound treatment 0.345 0.0178 0.7 0.349 0.0219 0.46 0.8198 0.979 2067574 IFLab1_003445 Clc1cc(C(=O)N2CCc3ccccc23)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M14 compound treatment 0.343 0.0158 0.62 0.357 0.0299 0.63 0.8826 1.0 1369842 IFLab1_003446 Cc1cc(O)cc2oc(C)c(Oc3ccccc3)c(=O)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M15 compound treatment 0.405 0.0778 3.06 0.398 0.0709 1.48 3.213 0.9449 1641075 IFLab1_003447 Oc1n(nc2ncncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M16 compound treatment 0.344 0.0168 0.66 0.339 0.0119 0.25 0.6441 0.9114 2067575 IFLab1_003448 Cc1ccc(C)n1n2cnc3scc(c4ccc(F)cc4)c3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M17 compound treatment 0.34 0.0128 0.5 0.342 0.0149 0.31 0.5772 0.9737 1720875 IFLab1_003449 CC(C)C1CCC(C)CC1OCC(O)CN2CC(C)OC(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M18 compound treatment 0.341 0.0138 0.54 0.332 0.00494 0.1 0.4571 0.8268 2067576 IFLab1_003450 Cc1nc(SCCO)c2c3CCCc3sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M19 compound treatment 0.335 0.00781 0.31 0.332 0.00494 0.1 0.2903 0.8956 1219582 IFLab1_003451 NCC(c1ccco1)c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M20 compound treatment 0.361 0.0338 1.33 0.349 0.0219 0.46 1.2647 0.8992 1478257 IFLab1_003452 OC(=O)c1cc(cc(c1)C(=O)O)N2C(=O)CSC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M21 compound treatment 0.334 0.00681 0.27 0.35 0.0229 0.48 0.5288 0.962 1349251 IFLab1_003453 COc1ccc(cc1Cl)N2C(SCC2=O)c3cccc(OC)c3OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M22 compound treatment 0.348 0.0208 0.82 0.343 0.0159 0.33 0.8145 0.9217 1584606 IFLab1_003454 CCN1CCN(CC1)S(=O)(=O)c2c(C)c(C)cc(C)c2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M23 mock treatment 0.322 -0.00519 -0.2 0.336 0.00894 0.19 -0.012 -0.0433 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 M24 positive control 0.088 -0.239 -9.4 0.087 -0.24 -5.02 -10.2021 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N01 compound treatment 0.343 0.0158 0.62 0.328 9.38E-4 0.02 0.4535 0.7291 1739652 IFLab1_003455 Cc1cc2nnc(SCC(=O)NCc3ccco3)n2c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N02 compound treatment 0.322 -0.00519 -0.2 0.314 -0.0131 -0.27 -0.3375 -0.9896 2067577 IFLab1_003456 Cc1ccc(cc1C)c2csc(n2)/C(=C/Nc3ccccc3)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N03 compound treatment 0.321 -0.00619 -0.24 0.31 -0.0171 -0.36 -0.4245 -0.9825 2067578 IFLab1_003457 COc1ncnc2n(ncc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N04 compound treatment 0.365 0.0378 1.49 0.357 0.0299 0.63 1.4943 0.9262 1554368 IFLab1_003458 Cc1ccc2OC(CC(=O)c2c1)c3cc(Br)cc4COCOc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N05 compound treatment 0.333 0.00581 0.23 0.325 -0.00206 -0.04 0.1311 0.5636 2067579 IFLab1_003459 C=CCNc1nc(c(s1)C(=O)Nc2cccnc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N06 compound treatment 0.33 0.00281 0.11 0.327 -6.25E-5 0.0 0.0773 0.6987 1290098 IFLab1_003460 COc1cc(cc(OC)c1OC)C(=O)N2Cc3ccccc3CC2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N07 compound treatment 0.394 0.0668 2.63 0.399 0.0719 1.51 2.922 0.9651 1694396 IFLab1_003461 COc1ccccc1c2nnc(NC(=O)C(C)SC3=NCCS3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N08 compound treatment 0.346 0.0188 0.74 0.338 0.0109 0.23 0.6849 0.8845 1174227 IFLab1_003462 CN(Cc1ccccc1)C(=O)C2CCCCN2S(=O)(=O)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N09 compound treatment 0.366 0.0388 1.53 0.37 0.0429 0.9 1.7144 0.9681 2067580 IFLab1_003463 CCOC(=O)CCCN1C(=O)/C(=C/c2cccc(OC)c2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N10 compound treatment 0.35 0.0228 0.9 0.349 0.0219 0.46 0.9588 0.9516 1584745 IFLab1_003464 Oc1ccc(C(=O)OCC(=O)c2ccccc2)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N11 compound treatment 0.342 0.0148 0.58 0.343 0.0159 0.33 0.6476 0.965 1581754 IFLab1_003465 O=C1C2C3CC(C=C3)C2C(=O)N1C4CCS(=O)(=O)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N12 compound treatment 0.348 0.0208 0.82 0.346 0.0189 0.4 0.8588 0.9446 1330006 IFLab1_003466 Cc1sc(NC(=O)CCC(=O)O)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N13 compound treatment 0.343 0.0158 0.62 0.348 0.0209 0.44 0.7494 0.9853 2067581 IFLab1_003467 N/C(=N/c1ccccc1)/C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N14 compound treatment 0.345 0.0178 0.7 0.354 0.0269 0.56 0.8938 0.9942 1571895 IFLab1_003468 OC(=O)CCCC(=O)Nc1nc(cs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N15 compound treatment 0.362 0.0348 1.37 0.381 0.0539 1.13 1.766 0.9954 2067582 IFLab1_003469 COc1ccc(cc1)c2c(oc3cc(O)ccc3c2=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N16 compound treatment 0.343 0.0158 0.62 0.341 0.0139 0.29 0.6459 0.9405 1113394 IFLab1_003470 Clc1ccccc1NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N17 compound treatment 0.338 0.0108 0.43 0.346 0.0189 0.4 0.5808 0.9994 1164418 IFLab1_003471 Cc1c(O)ccc(c2n[nH]cc2c3ccccc3)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N18 compound treatment 0.345 0.0178 0.7 0.34 0.0129 0.27 0.6867 0.9145 1552580 IFLab1_003472 CCOc1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N19 compound treatment 0.342 0.0148 0.58 0.345 0.0179 0.38 0.6772 0.9774 1143498 IFLab1_003473 CC(=O)Oc1ccc2c(=O)c(coc2c1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N20 compound treatment 0.342 0.0148 0.58 0.342 0.0149 0.31 0.6328 0.9574 1407757 IFLab1_003474 CCN(C1CCCCC1)C(=O)c2cc3cc(OC)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N21 compound treatment 0.347 0.0198 0.78 0.354 0.0269 0.56 0.9494 0.9874 2067583 IFLab1_003475 Cc1ccc(cc1)c2csc(n2)/C(=C\Nc3ccc(cc3)S(=O)(=O)N)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N22 compound treatment 0.38 0.0528 2.08 0.386 0.0589 1.23 2.3404 0.9691 2067584 IFLab1_003476 Oc1c(Cl)cc(Cl)cc1/C=N/C2=C(CCC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N23 mock treatment 0.333 0.00581 0.23 0.331 0.00394 0.08 0.2199 0.905 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 N24 positive control 0.087 -0.24 -9.44 0.088 -0.239 -5.0 -10.2151 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O01 compound treatment 0.329 0.00181 0.07 0.322 -0.00506 -0.11 -0.0245 -0.192 2067585 IFLab1_003477 Fc1cccc(Cl)c1CSc2ncnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O02 compound treatment 0.327 -1.88E-4 -0.01 0.32 -0.00706 -0.15 -0.1097 -0.7415 2067586 IFLab1_003478 C(Sc1nc2ccccc2s1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O03 compound treatment 0.31 -0.0172 -0.68 0.307 -0.0201 -0.42 -0.7747 -0.9738 2067587 IFLab1_003479 Fc1ccc(cc1)c2nnc3ccc(SCc4ccccc4)nn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O04 compound treatment 0.349 0.0218 0.86 0.339 0.0119 0.25 0.7831 0.8766 2067588 IFLab1_003480 N#CC(=C(/C=C/c1cccs1)C2CC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O05 compound treatment 0.349 0.0218 0.86 0.38 0.0529 1.11 1.3898 0.992 1312621 IFLab1_003481 O=C(CCSc1ccccc1)Nc2nc(cs2)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O06 compound treatment 0.371 0.0438 1.72 0.369 0.0419 0.88 1.8386 0.951 1732274 IFLab1_003482 OCCNc1nc(c2ccccc2)c3cc(Cl)ccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O07 compound treatment 0.325 -0.00219 -0.09 0.328 9.38E-4 0.02 -0.0469 -0.5321 2067589 IFLab1_003483 Oc1ccc(N/C(=N\S(=O)(=O)c2ccccc2)/c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O08 compound treatment 0.334 0.00681 0.27 0.334 0.00694 0.15 0.2921 0.9586 1441706 IFLab1_003484 O=C(NCc1ccc2OCOc2c1)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O09 compound treatment 0.329 0.00181 0.07 0.326 -0.00106 -0.02 0.0347 0.4644 1247662 IFLab1_003485 COc1ccccc1NC(=O)c2csc3CCCCc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O10 compound treatment 0.404 0.0768 3.02 0.416 0.0889 1.86 3.4516 0.973 1295311 IFLab1_003486 Brc1ccc(s1)C(=O)Nc2nc(cs2)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O11 compound treatment 0.347 0.0198 0.78 0.335 0.00794 0.17 0.6683 0.839 1427279 IFLab1_003487 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O12 compound treatment 0.379 0.0518 2.04 0.364 0.0369 0.77 1.9871 0.912 2067590 IFLab1_003488 Oc1ccc2c(=O)c(Oc3ccccc3)c(oc2c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O13 compound treatment 0.341 0.0138 0.54 0.346 0.0189 0.4 0.6642 0.988 1581630 IFLab1_003489 CCc1ccccc1NC(=O)c2cc(Cl)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O14 compound treatment 0.371 0.0438 1.72 0.373 0.0459 0.96 1.8978 0.962 2067591 IFLab1_003490 Cc1cc(O)cc2oc(c(Oc3ccccc3)c(=O)c12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O15 compound treatment 0.344 0.0168 0.66 0.34 0.0129 0.27 0.6589 0.9224 2067592 IFLab1_003491 CC1CCCN(CC(O)COCCC2(CC3CC4CC(C3)C2)C4)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O16 compound treatment 0.348 0.0208 0.82 0.351 0.0239 0.5 0.9328 0.9723 1176174 IFLab1_003492 CC(=O)Nc1cccc(Oc2nc(C)nc3sc4CCCCc4c23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O17 compound treatment 0.35 0.0228 0.9 0.352 0.0249 0.52 1.0032 0.9668 1592437 IFLab1_003493 OC(COc1ccc(Cl)cc1)CN2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O18 compound treatment 0.353 0.0258 1.01 0.346 0.0189 0.4 0.9979 0.9159 1705824 IFLab1_003494 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2ccc(Cl)cc2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O19 compound treatment 0.337 0.00981 0.39 0.34 0.0129 0.27 0.4642 0.985 2067593 IFLab1_003495 Cc1ccccc1NC(=O)c2cccc(NC(=O)C(F)(F)F)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O20 compound treatment 0.35 0.0228 0.9 0.344 0.0169 0.35 0.8849 0.9175 2067594 IFLab1_003496 O=C1CSC(=S)N1CC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O21 compound treatment 0.345 0.0178 0.7 0.345 0.0179 0.38 0.7606 0.9573 1073429 IFLab1_003497 O=C(Nc1ccc(cc1)C(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O22 compound treatment 0.344 0.0168 0.66 0.344 0.0169 0.35 0.718 0.9573 2067595 IFLab1_003498 Fc1ccc(cc1)N2CCN(CC2)S(=O)(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O23 mock treatment 0.335 0.00781 0.31 0.326 -0.00106 -0.02 0.2015 0.6542 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 O24 positive control 0.09 -0.237 -9.33 0.09 -0.237 -4.96 -10.1021 -0.9564 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P01 compound treatment 0.35 0.0228 0.9 0.335 0.00794 0.17 0.7517 0.824 2067596 IFLab1_003499 COc1ccc(cc1OC)C2=N/C(=C/c3ccco3)/C(=O)O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P02 compound treatment 0.33 0.00281 0.11 0.322 -0.00506 -0.11 0.0033 0.0214 2067597 IFLab1_003500 COc1cccc(N/C=C(\C#N)/c2nc(cs2)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P03 compound treatment 0.333 0.00581 0.23 0.318 -0.00906 -0.19 0.0275 0.0926 1597962 IFLab1_003501 Fc1ccc(cc1)c2nnc(N3CCOCC3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P04 compound treatment 0.345 0.0178 0.7 0.338 0.0109 0.23 0.6571 0.8918 1290708 IFLab1_003502 OC(=O)C1CCN(CC1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P05 compound treatment 0.345 0.0178 0.7 0.343 0.0159 0.33 0.7311 0.9424 2067598 IFLab1_003503 Cc1cc(=O)oc2cc(OCCOc3ccccc3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P06 compound treatment 0.354 0.0268 1.05 0.345 0.0179 0.38 1.0109 0.9033 2067599 IFLab1_003504 FC(F)(F)C1CCCC(C1)NC(=O)c2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P07 compound treatment 0.36 0.0328 1.29 0.359 0.0319 0.67 1.3848 0.9531 1742215 IFLab1_003505 COc1ccc(cc1)c2nnc(NC(=O)C(C)Sc3ccc(C)cc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P08 compound treatment 0.381 0.0538 2.12 0.372 0.0449 0.94 2.161 0.9333 2067600 IFLab1_003506 CC1CCCN(C1)c2ccc(cn2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P09 compound treatment 0.363 0.0358 1.41 0.358 0.0309 0.65 1.4534 0.9378 2067601 IFLab1_003507 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)Nc3ccccc3C(F)(F)F)C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P10 compound treatment 0.371 0.0438 1.72 0.364 0.0369 0.77 1.7646 0.9346 1192861 IFLab1_003508 O=C(OC1CCCCC1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P11 compound treatment 0.36 0.0328 1.29 0.359 0.0319 0.67 1.3848 0.9531 1430028 IFLab1_003509 CCS(=O)(=O)c1ccc(O)c(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P12 compound treatment 0.384 0.0568 2.23 0.365 0.0379 0.79 2.1409 0.9031 1374110 IFLab1_003510 COc1cccc(OC(=O)c2cc3ccccc3oc2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P13 compound treatment 0.366 0.0388 1.53 0.375 0.0479 1.0 1.7884 0.9793 1314980 IFLab1_003511 O=S(=O)(N=S(N1CCCCC1)N2CCCCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P14 compound treatment 0.407 0.0798 3.14 0.455 0.128 2.68 4.1121 0.9969 2067602 IFLab1_003512 Cc1sc(/N=C/c2c[nH]c3ccccc23)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P15 compound treatment 0.361 0.0338 1.33 0.363 0.0359 0.75 1.4718 0.9636 1451504 IFLab1_003513 Cc1ccccc1CC(=O)c2ccc(O)cc2O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P16 compound treatment 0.357 0.0298 1.17 0.356 0.0289 0.61 1.257 0.9528 1313479 IFLab1_003514 CN(C)S(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P17 compound treatment 0.362 0.0348 1.37 0.365 0.0379 0.79 1.5292 0.9664 1542694 IFLab1_003515 COc1ccc(c2n[nH]cc2c3ccccc3)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P18 compound treatment 0.352 0.0248 0.98 0.355 0.0279 0.58 1.1032 0.97 1661708 IFLab1_003516 CC(NC(=O)c1cc2ccccc2oc1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P19 compound treatment 0.355 0.0278 1.09 0.354 0.0269 0.56 1.1718 0.9525 1270685 IFLab1_003517 CN(C)Cc1c(O)ccc2c(=O)c(c(C)oc12)c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P20 compound treatment 0.366 0.0388 1.53 0.368 0.0409 0.86 1.6848 0.9627 2067603 IFLab1_003518 COc1ccc(O)c(/C=N/CCc2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P21 compound treatment 0.357 0.0298 1.17 0.358 0.0309 0.65 1.2866 0.9608 2067604 IFLab1_003519 NS(=O)(=O)c1ccc(N/C=C(/C#N)\c2nc(cs2)c3ccc(Cl)c(Cl)c3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P22 compound treatment 0.348 0.0208 0.82 0.35 0.0229 0.48 0.918 0.9677 1237246 IFLab1_003520 COc1ccc(Br)cc1S(=O)(=O)NCc2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P23 mock treatment 0.341 0.0138 0.54 0.333 0.00594 0.12 0.4719 0.847 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1421 P24 positive control 0.092 -0.235 -9.25 0.093 -0.234 -4.9 -10.0021 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A01 compound treatment 0.345 0.0206 0.81 0.349 0.0235 0.49 0.9194 0.9716 1409745 IFLab1_003521 O=C(NCc1ccc2OCOc2c1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A02 compound treatment 0.332 0.00756 0.3 0.326 5.0E-4 0.01 0.2177 0.7315 1784445 IFLab1_003522 CC/C(=C(\C#N)/c1nc2ccccc2[nH]1)/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A03 compound treatment 0.341 0.0166 0.65 0.338 0.0125 0.26 0.6454 0.9197 2067605 IFLab1_003523 Cc1ccc(/C=N/c2sc(C)c(C)c2C#N)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A04 compound treatment 0.351 0.0266 1.04 0.35 0.0245 0.51 1.101 0.9463 2067606 IFLab1_003524 COC1CS(=O)(=O)CC1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A05 compound treatment 0.324 -4.37E-4 -0.02 0.323 -0.0025 -0.05 -0.0492 -0.8926 1227048 IFLab1_003525 CC1CN(CCN1C(=O)c2cccc(Cl)c2)C(=O)c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A06 compound treatment 0.33 0.00556 0.22 0.327 0.0015 0.03 0.1768 0.8004 1326007 IFLab1_003526 COc1cccc2cc(c3nnc(Nc4ccccc4F)s3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A07 compound treatment 0.324 -4.37E-4 -0.02 0.33 0.0045 0.09 0.0544 0.5685 1345083 IFLab1_003527 O=C(Nc1ccncc1NC(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A08 compound treatment 0.347 0.0226 0.89 0.348 0.0225 0.47 0.9602 0.9561 1656482 IFLab1_003528 Clc1cccc(c1)C2SCCN2C(=O)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A09 compound treatment 0.325 5.63E-4 0.02 0.324 -0.0015 -0.03 -0.0066 -0.1708 1520132 IFLab1_003529 CC(C)N(C(=O)Cn1cnc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A10 compound treatment 0.325 5.63E-4 0.02 0.321 -0.0045 -0.09 -0.0509 -0.5267 1637825 IFLab1_003530 COC(=O)c1sc2ccccc2c1NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A11 compound treatment 0.336 0.0116 0.45 0.336 0.0105 0.22 0.4768 0.9444 1230553 IFLab1_003531 Clc1ccc(OCc2nc3ccccc3[nH]2)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A12 compound treatment 0.358 0.0336 1.32 0.359 0.0335 0.7 1.4288 0.9562 2067607 IFLab1_003532 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A13 compound treatment 0.347 0.0226 0.89 0.34 0.0145 0.3 0.8418 0.8979 1243864 IFLab1_003533 COc1ccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A14 compound treatment 0.331 0.00656 0.26 0.321 -0.0045 -0.09 0.1159 0.4218 2067608 IFLab1_003534 CCNc1nc(NCC)nc(SCC(=O)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A15 compound treatment 0.333 0.00856 0.34 0.348 0.0225 0.47 0.571 0.9865 2067609 IFLab1_003535 C=CCn1nnnc1SCC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A16 compound treatment 0.426 0.102 3.99 0.401 0.0755 1.58 3.9408 0.9177 1331694 IFLab1_003536 COc1ccc(cc1)c2cc3ccccn3c2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A17 compound treatment 0.329 0.00456 0.18 0.326 5.0E-4 0.01 0.1342 0.7471 1166854 IFLab1_003537 C(N1CCN(CC1)c2ccccc2)c3cn4cccnc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A18 compound treatment 0.328 0.00356 0.14 0.33 0.0045 0.09 0.1656 0.9813 2067610 IFLab1_003538 O=C(Nc1nccs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A19 compound treatment 0.327 0.00256 0.1 0.349 0.0235 0.49 0.419 0.8346 2067611 IFLab1_003539 COc1ccc(cc1)C(=O)CNC2=NCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A20 compound treatment 0.322 -0.00244 -0.1 0.323 -0.0025 -0.05 -0.1048 -0.9595 1700419 IFLab1_003540 CCOc1ccc(cc1)S(=O)(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A21 compound treatment 0.345 0.0206 0.81 0.318 -0.0075 -0.16 0.4607 0.5594 1164353 IFLab1_003541 OC(=O)CNC(=O)COc1cccc(Br)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A22 compound treatment 0.315 -0.00944 -0.37 0.341 0.0155 0.32 -0.033 -0.067 1152002 IFLab1_003542 COc1ccccc1NC(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A23 mock treatment 0.319 -0.00544 -0.21 0.321 -0.0045 -0.09 -0.2178 -0.9321 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 A24 positive control 0.078 -0.246 -9.69 0.078 -0.248 -5.18 -10.5137 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B01 compound treatment 0.333 0.00856 0.34 0.338 0.0125 0.26 0.423 0.9922 1677123 IFLab1_003543 Cc1cc(=O)cc(C)n1c2ccc(cc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B02 compound treatment 0.335 0.0106 0.42 0.32 -0.0055 -0.12 0.2123 0.4926 2067612 IFLab1_003544 CC(=C)C(=O)Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B03 compound treatment 0.326 0.00156 0.06 0.325 -5.0E-4 -0.01 0.036 0.5783 1207063 IFLab1_003545 CCOC(=O)C1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B04 compound treatment 0.328 0.00356 0.14 0.332 0.0065 0.14 0.1952 0.9999 1980352 IFLab1_003546 CCCc1nnc2SCC(=Nn12)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B05 compound treatment 0.315 -0.00944 -0.37 0.32 -0.0055 -0.12 -0.3438 -0.8848 1398133 IFLab1_003547 Cn1c(=NC(=O)c2nc3ccccc3s2)sc4cc(Cl)ccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B06 compound treatment 0.327 0.00256 0.1 0.326 5.0E-4 0.01 0.0786 0.7764 2067613 IFLab1_003548 COc1ccc(cc1)C(=O)CSc2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B07 compound treatment 0.368 0.0436 1.71 0.357 0.0315 0.66 1.6772 0.9139 2067614 IFLab1_003549 O=C(Nc1ccc2sccc2c1)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B08 compound treatment 0.366 0.0416 1.63 0.372 0.0465 0.97 1.8436 0.9693 2067615 IFLab1_003550 CCc1ccc(/C=C/2\SC(=S)N(CCCC(=O)Nc3cccnc3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B09 compound treatment 0.336 0.0116 0.45 0.3 -0.0255 -0.53 -0.0559 -0.0797 1145470 IFLab1_003551 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B10 compound treatment 0.339 0.0146 0.57 0.327 0.0015 0.03 0.4271 0.7448 2067616 IFLab1_003552 Cn1c(=NC(=O)c2ccc(Br)s2)sc3cc(F)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B11 compound treatment 0.336 0.0116 0.45 0.336 0.0105 0.22 0.4768 0.9444 1265904 IFLab1_003553 CCC(=O)Nc1ccc(cc1)c2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B12 compound treatment 0.354 0.0296 1.16 0.356 0.0305 0.64 1.2732 0.9602 2067617 IFLab1_003554 NC(=O)c1ccc(N/C=C(\C#N)/c2nc(cs2)c3cccc4ccccc34)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B13 compound treatment 0.339 0.0146 0.57 0.333 0.0075 0.16 0.5158 0.8689 2067618 IFLab1_003555 CC(Sc1nnc(o1)c2cccc(Br)c2)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B14 compound treatment 0.316 -0.00844 -0.33 0.329 0.0035 0.07 -0.1828 -0.538 1134927 IFLab1_003556 CC(C)(C)NC(=O)C1C2CC(C)(NC1=O)Oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B15 compound treatment 0.327 0.00256 0.1 0.338 0.0125 0.26 0.2562 0.914 1650896 IFLab1_003557 CCOC(=O)c1c(C)[nH]c(C(=O)CC(=O)OC)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B16 compound treatment 0.341 0.0166 0.65 0.335 0.0095 0.2 0.601 0.8828 1545249 IFLab1_003558 Cc1ccc(OCC(O)CN2CCCCC2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B17 compound treatment 0.404 0.0796 3.13 0.39 0.0645 1.35 3.1664 0.9294 2067619 IFLab1_003559 OC(=O)c1cccc(c1)N2C(=O)/C(=C\c3ccc4OCOc4c3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B18 compound treatment 0.328 0.00356 0.14 0.323 -0.0025 -0.05 0.0621 0.415 1351386 IFLab1_003560 COc1ccccc1N2CCN(CC(O)COc3ccccc3CC=C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B19 compound treatment 0.337 0.0126 0.49 0.338 0.0125 0.26 0.5342 0.9558 1166032 IFLab1_003561 CC(C)c1ccc(OCC(C)NC(=O)c2cccs2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B20 compound treatment 0.345 0.0206 0.81 0.342 0.0165 0.35 0.8158 0.928 1068756 IFLab1_003562 Cc1ccc(cc1)S(=O)(=O)CC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B21 compound treatment 0.341 0.0166 0.65 0.34 0.0145 0.3 0.675 0.9396 1597132 IFLab1_003563 CCC(=O)Oc1ccc(cc1)N2C(=O)CCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B22 compound treatment 0.332 0.00756 0.3 0.338 0.0125 0.26 0.3952 0.998 1604489 IFLab1_003564 O=S(=O)(N1CCc2ccccc12)c3cccc4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B23 mock treatment 0.326 0.00156 0.06 0.333 0.0075 0.16 0.1544 0.9162 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 B24 positive control 0.078 -0.246 -9.69 0.078 -0.248 -5.18 -10.5137 -0.9569 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C01 compound treatment 0.332 0.00756 0.3 0.339 0.0135 0.28 0.41 0.9997 1280715 IFLab1_003565 COc1ccc(Br)cc1S(=O)(=O)n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C02 compound treatment 0.325 5.63E-4 0.02 0.321 -0.0045 -0.09 -0.0509 -0.5267 2067620 IFLab1_003566 FC(F)(F)SCC(=O)Nc1ccc(I)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C03 compound treatment 0.322 -0.00244 -0.1 0.329 0.0035 0.07 -0.016 -0.1325 1475116 IFLab1_003567 COc1ccc2cc(ccc2c1)S(=O)(=O)N3CCN(C)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C04 compound treatment 0.337 0.0126 0.49 0.34 0.0145 0.3 0.5638 0.9726 1224373 IFLab1_003568 OC1CS(=O)(=O)CC1N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C05 compound treatment 0.331 0.00656 0.26 0.331 0.0055 0.12 0.2638 0.9338 1490334 IFLab1_003569 CC1CN(CCN1C(=O)c2ccccc2Cl)C(=O)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C06 compound treatment 0.327 0.00256 0.1 0.337 0.0115 0.24 0.2414 0.9253 1327035 IFLab1_003570 CCOc1cccc2cc(C(=O)N)c(=Nc3ccccc3F)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C07 compound treatment 0.34 0.0156 0.61 0.322 -0.0035 -0.07 0.3809 0.6181 1117794 IFLab1_003571 O=C(Nc1ccncc1NC(=O)C2CC2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C08 compound treatment 0.342 0.0176 0.69 0.34 0.0145 0.3 0.7028 0.9318 1303507 IFLab1_003572 CCC(=O)Nc1cccc(c1)c2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C09 compound treatment 0.341 0.0166 0.65 0.335 0.0095 0.2 0.601 0.8828 2067621 IFLab1_003573 CCCn1c(CCCO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C10 compound treatment 0.332 0.00756 0.3 0.333 0.0075 0.16 0.3212 0.9554 1383855 IFLab1_003574 COC(=O)c1sc2ccccc2c1NC(=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C11 compound treatment 0.342 0.0176 0.69 0.34 0.0145 0.3 0.7028 0.9318 1142340 IFLab1_003575 COc1cc(Cn2c(nc3ccccc23)c4ccc(O)c(OC)c4)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C12 compound treatment 0.324 -4.37E-4 -0.02 0.328 0.0025 0.05 0.0248 0.4509 1385320 IFLab1_003576 O=C(Nc1ccccc1C#N)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C13 compound treatment 0.37 0.0456 1.79 0.363 0.0375 0.78 1.8216 0.9314 2067622 IFLab1_003577 Brc1ccc(NC2=Nc3ccccc3SC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C14 compound treatment 0.336 0.0116 0.45 0.34 0.0145 0.3 0.536 0.9807 1455353 IFLab1_003578 O=C(CSc1nc2ccccc2c(=O)n1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C15 compound treatment 0.337 0.0126 0.49 0.332 0.0065 0.14 0.4454 0.8695 1569227 IFLab1_003579 COc1ccc(cc1)C(=O)CSc2nnnn2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C16 compound treatment 0.337 0.0126 0.49 0.338 0.0125 0.26 0.5342 0.9558 1182009 IFLab1_003580 CC(C)N(C(=O)CSc1ccccc1C(=O)O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C17 compound treatment 0.336 0.0116 0.45 0.337 0.0115 0.24 0.4916 0.9558 2067623 IFLab1_003581 Cn1cnn2cc(c3ccccc3)[n+](C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C18 compound treatment 0.338 0.0136 0.53 0.335 0.0095 0.2 0.5176 0.9096 1360104 IFLab1_003582 COc1ccccc1N2CCN(CC2)C(=O)Oc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C19 compound treatment 0.332 0.00756 0.3 0.34 0.0145 0.3 0.4248 0.9999 1730817 IFLab1_003583 COC(=O)c1ccccc1Sc2c(nc3ncccn23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C20 compound treatment 0.338 0.0136 0.53 0.323 -0.0025 -0.05 0.3401 0.6347 1207062 IFLab1_003584 OCCNS(=O)(=O)c1cc(Cl)ccc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C21 compound treatment 0.341 0.0166 0.65 0.333 0.0075 0.16 0.5714 0.8531 1720395 IFLab1_003585 O=C(COc1cccc2ccccc12)OC3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C22 compound treatment 0.334 0.00956 0.38 0.333 0.0075 0.16 0.3768 0.9249 1409165 IFLab1_003586 COc1ccc(cc1)S(=O)(=O)N2C(C)CCCC2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C23 mock treatment 0.324 -4.37E-4 -0.02 0.324 -0.0015 -0.03 -0.0344 -0.9599 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 C24 positive control 0.078 -0.246 -9.69 0.079 -0.247 -5.16 -10.4989 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D01 compound treatment 0.348 0.0236 0.93 0.345 0.0195 0.41 0.9436 0.9321 2067624 IFLab1_003587 OC(=O)CC1(OCCO1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D02 compound treatment 0.335 0.0106 0.42 0.329 0.0035 0.07 0.3454 0.8192 1400553 IFLab1_003588 Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D03 compound treatment 0.333 0.00856 0.34 0.328 0.0025 0.05 0.275 0.8073 1107771 IFLab1_003589 CN1CCN(Cc2oc(CO)cc(=O)c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D04 compound treatment 0.332 0.00756 0.3 0.335 0.0095 0.2 0.3508 0.9808 2067625 IFLab1_003590 CCCc1nnc2SCC(=Nn12)c3ccc(OC)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D05 compound treatment 0.402 0.0776 3.05 0.385 0.0595 1.25 3.0368 0.9219 1309648 IFLab1_003591 Fc1cccc(F)c1C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D06 compound treatment 0.341 0.0166 0.65 0.334 0.0085 0.18 0.5862 0.8684 2067626 IFLab1_003592 Cc1nnc2SCC(=Nn12)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D07 compound treatment 0.371 0.0466 1.83 0.363 0.0375 0.78 1.8494 0.9285 1710483 IFLab1_003593 O=C(Nc1ccc2sccc2c1)c3ccc(cc3)S(=O)(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D08 compound treatment 0.336 0.0116 0.45 0.342 0.0165 0.35 0.5656 0.9908 2067627 IFLab1_003594 CCc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3CCCC3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D09 compound treatment 0.342 0.0176 0.69 0.335 0.0095 0.2 0.6288 0.8751 2067628 IFLab1_003595 OC(=O)c1sc2cc(Cl)ccc2c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D10 compound treatment 0.335 0.0106 0.42 0.336 0.0105 0.22 0.449 0.9557 2067629 IFLab1_003596 COc1cccc2sc(=NC(=O)c3cccc(c3)C(F)(F)F)n(C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D11 compound treatment 0.344 0.0196 0.77 0.339 0.0135 0.28 0.7436 0.9075 2067630 IFLab1_003597 Cc1ccc(cc1)C(=O)CSc2nnc3[nH]c(=O)cc(C)n23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D12 compound treatment 0.34 0.0156 0.61 0.336 0.0105 0.22 0.588 0.9045 1220393 IFLab1_003598 COc1ccc(Br)cc1S(=O)(=O)n2ccnc2C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D13 compound treatment 0.33 0.00556 0.22 0.337 0.0115 0.24 0.3248 0.9989 2067631 IFLab1_003599 Cc1ccc(NC2=NCCOC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D14 compound treatment 0.34 0.0156 0.61 0.335 0.0095 0.2 0.5732 0.891 1631142 IFLab1_003600 Cc1nc2ccccc2n1CC(=O)N3CC(=O)Nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D15 compound treatment 0.334 0.00956 0.38 0.323 -0.0025 -0.05 0.2289 0.6029 2067632 IFLab1_003601 O=c1ccc2ccc(OCCOc3ccc4ccc(=O)oc4c3)cc2o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D16 compound treatment 0.333 0.00856 0.34 0.333 0.0075 0.16 0.349 0.9397 1559652 IFLab1_003602 CC1CCCN(CC(O)COCc2ccc(Cl)cc2)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D17 compound treatment 0.336 0.0116 0.45 0.334 0.0085 0.18 0.4472 0.9161 2067633 IFLab1_003603 O=S(=O)(/C=C/c1ccccc1)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D18 compound treatment 0.323 -0.00144 -0.06 0.318 -0.0075 -0.16 -0.1509 -0.9049 1444119 IFLab1_003604 Cc1cc(OCC(O)CN2CCN(CC2)c3ccccn3)ccc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D19 compound treatment 0.339 0.0146 0.57 0.334 0.0085 0.18 0.5306 0.8851 1432502 IFLab1_003605 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D20 compound treatment 0.307 -0.0174 -0.69 0.305 -0.0205 -0.43 -0.7881 -0.9745 1559961 IFLab1_003606 Oc1c(ccc2cccnc12)C(N3CCCC3)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D21 compound treatment 0.346 0.0216 0.85 0.341 0.0155 0.32 0.8288 0.9131 1239975 IFLab1_003607 CCC(=O)Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D22 compound treatment 0.334 0.00956 0.38 0.341 0.0155 0.32 0.4952 0.9973 1400810 IFLab1_003608 O=S(=O)(N1CCc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D23 mock treatment 0.325 5.63E-4 0.02 0.322 -0.0035 -0.07 -0.0362 -0.4725 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 D24 positive control 0.079 -0.245 -9.65 0.08 -0.246 -5.14 -10.4563 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E01 compound treatment 0.333 0.00856 0.34 0.328 0.0025 0.05 0.275 0.8073 1627518 IFLab1_003609 Cc1ccc(C(=O)O)c(c1)C(=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E02 compound treatment 0.351 0.0266 1.04 0.355 0.0295 0.62 1.175 0.9685 2067634 IFLab1_003610 FC(F)(F)c1ccc2sc(CC#N)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E03 compound treatment 0.339 0.0146 0.57 0.338 0.0125 0.26 0.5898 0.937 1530960 IFLab1_003611 COc1ccc2cc(ccc2c1)S(=O)(=O)n3nnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E04 compound treatment 0.328 0.00356 0.14 0.337 0.0115 0.24 0.2692 0.9668 1083304 IFLab1_003612 O=S1(=O)CC(SC#N)C=C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E05 compound treatment 0.33 0.00556 0.22 0.33 0.0045 0.09 0.2212 0.9291 1193288 IFLab1_003613 COc1ccc(C)cc1S(=O)(=O)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E06 compound treatment 0.33 0.00556 0.22 0.328 0.0025 0.05 0.1916 0.8522 1737734 IFLab1_003614 CCOc1cccc2cc(C(=O)N)c(=Nc3ccc(F)cc3)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E07 compound treatment 0.336 0.0116 0.45 0.331 0.0055 0.12 0.4028 0.859 1655301 IFLab1_003615 COC(=O)c1sc(cc1NC(=O)C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E08 compound treatment 0.345 0.0206 0.81 0.336 0.0105 0.22 0.727 0.8678 1496658 IFLab1_003616 Cc1nc(cs1)c2cccc(NC(=O)c3cc4ccccc4oc3=O)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E09 compound treatment 0.341 0.0166 0.65 0.341 0.0155 0.32 0.6898 0.9482 2067635 IFLab1_003617 C=CCn1c(nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E10 compound treatment 0.356 0.0316 1.24 0.369 0.0435 0.91 1.5212 0.9884 1221120 IFLab1_003618 COC(=O)c1sc2ccccc2c1NC(=O)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E11 compound treatment 0.358 0.0336 1.32 0.354 0.0285 0.6 1.3548 0.9356 1553473 IFLab1_003619 CCc1cccc(CC)c1N(COC)C(=O)CSc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E12 compound treatment 0.331 0.00656 0.26 0.343 0.0175 0.37 0.4414 0.9853 2067636 IFLab1_003620 O=C(Cn1nnc(n1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E13 compound treatment 0.307 -0.0174 -0.69 0.33 0.0045 0.09 -0.4182 -0.6043 2067637 IFLab1_003621 O=C1C(CCc2ccccc12)Sc3nnc(o3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E14 compound treatment 0.37 0.0456 1.79 0.35 0.0245 0.51 1.6293 0.8744 2067638 IFLab1_003622 CC(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E15 compound treatment 0.344 0.0196 0.77 0.34 0.0145 0.3 0.7584 0.9173 2067639 IFLab1_003623 C/C(=C(/C#N)\c1nnc2CCCCCn12)/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E16 compound treatment 0.34 0.0156 0.61 0.341 0.0155 0.32 0.662 0.9559 2067640 IFLab1_003624 CC1CSC(=N1)Nc2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E17 compound treatment 0.346 0.0216 0.85 0.333 0.0075 0.16 0.7105 0.824 2067641 IFLab1_003625 Cc1n[n+](CC(=O)c2ccc(Br)cc2)c(N)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E18 compound treatment 0.344 0.0196 0.77 0.333 0.0075 0.16 0.6549 0.8342 2067642 IFLab1_003626 O=C(Oc1ccccc1)Oc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E19 compound treatment 0.335 0.0106 0.42 0.332 0.0065 0.14 0.3898 0.8921 1149978 IFLab1_003627 OC(=O)c1ccc(CNC2CCS(=O)(=O)C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E20 compound treatment 0.346 0.0216 0.85 0.338 0.0125 0.26 0.7844 0.8841 2067643 IFLab1_003628 CN(C)S(=O)(=O)c1c(C)cc(C)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E21 compound treatment 0.361 0.0366 1.44 0.355 0.0295 0.62 1.453 0.9287 1420932 IFLab1_003629 NS(=O)(=O)c1ccc(NC(=O)COc2cccc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E22 compound treatment 0.318 -0.00644 -0.25 0.324 -0.0015 -0.03 -0.2012 -0.7888 1403291 IFLab1_003630 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E23 mock treatment 0.322 -0.00244 -0.1 0.32 -0.0055 -0.12 -0.1492 -0.9959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 E24 positive control 0.081 -0.243 -9.57 0.081 -0.245 -5.12 -10.3859 -0.957 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F01 compound treatment 0.331 0.00656 0.26 0.329 0.0035 0.07 0.2342 0.8733 2067644 IFLab1_003631 C1CN=C(Nc2ccccc2)S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F02 compound treatment 0.32 -0.00444 -0.17 0.321 -0.0045 -0.09 -0.19 -0.9581 1431348 IFLab1_003632 Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F03 compound treatment 0.322 -0.00244 -0.1 0.318 -0.0075 -0.16 -0.1787 -0.972 1512484 IFLab1_003633 OC(=O)c1ccc(cc1)n2c(cc3C(=O)CCCc32)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F04 compound treatment 0.328 0.00356 0.14 0.332 0.0065 0.14 0.1952 0.9999 1486736 IFLab1_003634 Cc1ccc(NC(=O)CSc2nnc3CCCCCn23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F05 compound treatment 0.341 0.0166 0.65 0.344 0.0185 0.39 0.7342 0.9692 2067645 IFLab1_003635 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)/C=C/c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F06 compound treatment 0.336 0.0116 0.45 0.344 0.0185 0.39 0.5952 0.9968 2067646 IFLab1_003636 Clc1ccc(cc1)C(=O)CSc2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F07 compound treatment 0.338 0.0136 0.53 0.341 0.0155 0.32 0.6064 0.9716 1637291 IFLab1_003637 O=C(CCc1ccccc1)Nc2ccc3sccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F08 compound treatment 0.342 0.0176 0.69 0.342 0.0165 0.35 0.7324 0.9487 1502473 IFLab1_003638 NC(=O)c1oc2ccccc2c1NC(=O)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F09 compound treatment 0.343 0.0186 0.73 0.338 0.0125 0.26 0.701 0.9042 1560840 IFLab1_003639 O=S(=O)(N1CCc2ccccc2C1)c3cccc4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F10 compound treatment 0.344 0.0196 0.77 0.349 0.0235 0.49 0.8916 0.9766 1179572 IFLab1_003640 COc1cccc2sc(=NC(=O)C3CCCCC3)n(C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F11 compound treatment 0.339 0.0146 0.57 0.336 0.0105 0.22 0.5602 0.9135 2067647 IFLab1_003641 Nc1ccc(cc1)S(=O)(=O)/N=C/2\CCCCCN2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F12 compound treatment 0.339 0.0146 0.57 0.34 0.0145 0.3 0.6194 0.9559 1682798 IFLab1_003642 Cc1c(Cl)ccc(c1Cl)S(=O)(=O)Nc2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F13 compound treatment 0.365 0.0406 1.59 0.365 0.0395 0.83 1.7122 0.9532 1211371 IFLab1_003643 CCOC(=O)c1c(C)oc2cc(Br)c(O)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F14 compound treatment 0.342 0.0176 0.69 0.335 0.0095 0.2 0.6288 0.8751 1205440 IFLab1_003644 COc1cccc(OCC(O)CN2CCCCC2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F15 compound treatment 0.329 0.00456 0.18 0.347 0.0215 0.45 0.445 0.9187 1298587 IFLab1_003645 CC(C)(C)c1ccc(cc1)C(=O)N2CCCCCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F16 compound treatment 0.342 0.0176 0.69 0.339 0.0135 0.28 0.688 0.9222 1699254 IFLab1_003646 OCCN1CCN(CC(O)COCc2ccc(Cl)cc2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F17 compound treatment 0.38 0.0556 2.18 0.37 0.0445 0.93 2.2032 0.9278 2067648 IFLab1_003647 O=C/1N(C(=S)S\C1=C/c2cccnc2)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F18 compound treatment 0.342 0.0176 0.69 0.335 0.0095 0.2 0.6288 0.8751 1181961 IFLab1_003648 COc1cccc(OC)c1OCC(O)CN2CCN(C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F19 compound treatment 0.329 0.00456 0.18 0.337 0.0115 0.24 0.297 0.9895 1705677 IFLab1_003649 CC(C)c1ccc(OCC(C)NC(=O)c2ccc(Br)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F20 compound treatment 0.257 -0.0674 -2.65 0.261 -0.0645 -1.35 -2.8293 -0.9509 1667146 IFLab1_003650 Oc1c(ccc2cccnc12)C(Nc3ccc(F)cc3)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F21 compound treatment 0.338 0.0136 0.53 0.336 0.0105 0.22 0.5324 0.9232 1613489 IFLab1_003651 CCC(=O)Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F22 compound treatment 0.365 0.0406 1.59 0.352 0.0265 0.55 1.5198 0.9001 1705192 IFLab1_003652 Clc1ccc(cc1)C2CC(=O)n3c(S2)nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F23 mock treatment 0.322 -0.00244 -0.1 0.323 -0.0025 -0.05 -0.1048 -0.9595 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 F24 positive control 0.081 -0.243 -9.57 0.081 -0.245 -5.12 -10.3859 -0.957 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G01 compound treatment 0.338 0.0136 0.53 0.341 0.0155 0.32 0.6064 0.9716 2067649 IFLab1_003653 Cc1cc(C)c(C(=O)NCCCN2CCOCC2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G02 compound treatment 0.334 0.00956 0.38 0.331 0.0055 0.12 0.3472 0.8831 2067650 IFLab1_003654 CCn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G03 compound treatment 0.32 -0.00444 -0.17 0.31 -0.0155 -0.32 -0.3527 -0.9577 1341016 IFLab1_003655 COc1ccc(I)cc1S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G04 compound treatment 0.31 -0.0144 -0.57 0.314 -0.0115 -0.24 -0.5716 -0.927 1086344 IFLab1_003656 C=CS(=O)(=O)Cc1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G05 compound treatment 0.321 -0.00344 -0.14 0.321 -0.0045 -0.09 -0.1622 -0.9844 1480776 IFLab1_003657 COc1ccc(C)cc1S(=O)(=O)n2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G06 compound treatment 0.327 0.00256 0.1 0.323 -0.0025 -0.05 0.0342 0.3017 2067651 IFLab1_003658 FC(F)(F)c1cccc(Nc2nnc(s2)c3cc4ccccc4oc3=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G07 compound treatment 0.329 0.00456 0.18 0.328 0.0025 0.05 0.1638 0.8768 1271620 IFLab1_003659 COC(=O)c1sc(cc1NC(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G08 compound treatment 0.317 -0.00744 -0.29 0.321 -0.0045 -0.09 -0.2734 -0.8898 2067652 IFLab1_003660 Cc1nc(cs1)c2ccc(/N=C/c3cc(Br)ccc3O)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G09 compound treatment 0.322 -0.00244 -0.1 0.328 0.0025 0.05 -0.0308 -0.2819 2067653 IFLab1_003661 C=CCn1c(Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G10 compound treatment 0.343 0.0186 0.73 0.341 0.0155 0.32 0.7454 0.9333 1416878 IFLab1_003662 COC(=O)c1sc2ccccc2c1NC(=O)COc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G11 compound treatment 0.341 0.0166 0.65 0.334 0.0085 0.18 0.5862 0.8684 1590989 IFLab1_003663 CCc1cccc(CC)c1N(COC)C(=O)Cn2c(nc3ccccc23)C(C)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G12 compound treatment 0.332 0.00756 0.3 0.325 -5.0E-4 -0.01 0.2029 0.6818 1503144 IFLab1_003664 CC(=O)n1c(N)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G13 compound treatment 0.312 -0.0124 -0.49 0.333 0.0075 0.16 -0.2348 -0.4572 2067654 IFLab1_003665 CC(C)N(C(=O)CSc1nnc(o1)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G14 compound treatment 0.337 0.0126 0.49 0.341 0.0155 0.32 0.5786 0.9792 2067655 IFLab1_003666 Brc1cccc(c1)c2nnc(Nc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G15 compound treatment 0.342 0.0176 0.69 0.342 0.0165 0.35 0.7324 0.9487 2067656 IFLab1_003667 Cc1cc(NC(=O)CCN2C(=O)/C(=C\c3ccccc3F)/SC2=S)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G16 compound treatment 0.334 0.00956 0.38 0.335 0.0095 0.2 0.4064 0.9556 1547461 IFLab1_003668 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G17 compound treatment 0.342 0.0176 0.69 0.336 0.0105 0.22 0.6436 0.8882 2067657 IFLab1_003669 N#CCc1ncc(CSc2nnnn2c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G18 compound treatment 0.327 0.00256 0.1 0.331 0.0055 0.12 0.1526 0.9978 1007899 IFLab1_003670 O=C(Oc1ccc2ccccc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G19 compound treatment 0.318 -0.00644 -0.25 0.337 0.0115 0.24 -0.0088 -0.0252 1476561 IFLab1_003671 CN1CCN(CC1)C(=O)COc2ccc(Oc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G20 compound treatment 0.366 0.0416 1.63 0.364 0.0385 0.81 1.7252 0.9469 1376608 IFLab1_003672 OCCNS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G21 compound treatment 0.333 0.00856 0.34 0.337 0.0115 0.24 0.4082 0.9865 1532797 IFLab1_003673 CCOC(=O)Cc1csc(NC(=O)COc2cccc3ccccc23)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G22 compound treatment 0.331 0.00656 0.26 0.332 0.0065 0.14 0.2786 0.9553 1730280 IFLab1_003674 O=C(Oc1ccccc1)Oc2ccc3ccc(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G23 mock treatment 0.318 -0.00644 -0.25 0.319 -0.0065 -0.14 -0.2752 -0.9576 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 G24 positive control 0.081 -0.243 -9.57 0.082 -0.243 -5.1 -10.3711 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H01 compound treatment 0.342 0.0176 0.69 0.338 0.0125 0.26 0.6732 0.9117 1666173 IFLab1_003675 O=C1C(CN2CCCCC2)CCCC1CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H02 compound treatment 0.318 -0.00644 -0.25 0.325 -5.0E-4 -0.01 -0.1864 -0.7357 1172015 IFLab1_003676 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(O)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H03 compound treatment 0.349 0.0246 0.97 0.329 0.0035 0.07 0.7347 0.7586 2067658 IFLab1_003677 Clc1ccc(cc1)C2C=C(Nc3ncnn23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H04 compound treatment 0.322 -0.00244 -0.1 0.331 0.0055 0.12 0.0136 0.0909 1328685 IFLab1_003678 COc1ccc(NC(=O)CSc2nnc3CCCCCn23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H05 compound treatment 0.37 0.0456 1.79 0.37 0.0445 0.93 1.9252 0.9535 2067659 IFLab1_003679 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc(Br)s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H06 compound treatment 0.316 -0.00844 -0.33 0.338 0.0125 0.26 -0.0496 -0.1174 1111757 IFLab1_003680 Fc1ccc(cc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H07 compound treatment 0.355 0.0306 1.2 0.339 0.0135 0.28 1.0495 0.8502 1734773 IFLab1_003681 O=C(CN1C(=O)CCC1=O)Nc2ccc3sccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H08 compound treatment 0.343 0.0186 0.73 0.336 0.0105 0.22 0.6714 0.8809 1304791 IFLab1_003682 COc1cccc2sc(=NC(=O)c3cccc4ccccc34)n(C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H09 compound treatment 0.334 0.00956 0.38 0.347 0.0215 0.45 0.584 0.996 1621309 IFLab1_003683 Cc1ccccc1NC(=O)CSc2ccccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H10 compound treatment 0.381 0.0566 2.22 0.366 0.0405 0.85 2.1718 0.9126 1634225 IFLab1_003684 Cc1ccc(cc1C)C(=O)Nc2c(oc3ccccc23)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H11 compound treatment 0.758 0.434 17.05 0.773 0.448 9.36 18.6756 0.9602 2067660 IFLab1_003685 Cc1ccccc1NC(=O)CSC2=NCCN2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H12 compound treatment 0.344 0.0196 0.77 0.315 -0.0105 -0.22 0.3885 0.4857 1650383 IFLab1_003686 CCC1CCCCN1S(=O)(=O)c2ccc3cc(OC)ccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H13 compound treatment 0.361 0.0366 1.44 0.353 0.0275 0.58 1.4234 0.9193 1536420 IFLab1_003687 CCOC(=O)c1c(C)oc2cc(Br)c(OCC#N)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H14 compound treatment 0.339 0.0146 0.57 0.343 0.0175 0.37 0.6638 0.9767 1634405 IFLab1_003688 COc1cccc(OCC(O)CN2CC(C)CC(C)C2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H15 compound treatment 0.337 0.0126 0.49 0.343 0.0175 0.37 0.6082 0.9892 2067661 IFLab1_003689 COC(=O)c1c(NC(=O)CCNCc2ccco2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H16 compound treatment 0.344 0.0196 0.77 0.335 0.0095 0.2 0.6844 0.8616 1404662 IFLab1_003690 CCOC(=O)C1CCN(CC(O)COCc2ccc(Cl)cc2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H17 compound treatment 0.342 0.0176 0.69 0.331 0.0055 0.12 0.5697 0.8137 2067662 IFLab1_003691 Cc1sc2ncnc(SCC(=O)c3ccc4OCCOc4c3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H18 compound treatment 0.332 0.00756 0.3 0.33 0.0045 0.09 0.2768 0.8876 1544274 IFLab1_003692 CC1CCCCN1CC(O)COc2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H19 compound treatment 0.339 0.0146 0.57 0.337 0.0115 0.24 0.575 0.9259 1291788 IFLab1_003693 CC(C)(C)c1csc(NC(=O)c2ccc(Br)o2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H20 compound treatment 0.339 0.0146 0.57 0.335 0.0095 0.2 0.5454 0.8999 1455013 IFLab1_003694 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H21 compound treatment 0.339 0.0146 0.57 0.341 0.0155 0.32 0.6342 0.9638 2067663 IFLab1_003695 COC(=O)c1ccc(cc1)N2C(=O)CCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H22 compound treatment 0.331 0.00656 0.26 0.349 0.0235 0.49 0.5302 0.9547 1158912 IFLab1_003696 COc1ccc(cc1)C2CC(=O)n3c(S2)nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H23 mock treatment 0.325 5.63E-4 0.02 0.321 -0.0045 -0.09 -0.0509 -0.5267 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 H24 positive control 0.082 -0.242 -9.53 0.084 -0.241 -5.05 -10.3138 -0.956 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I01 compound treatment 0.346 0.0216 0.85 0.341 0.0155 0.32 0.8288 0.9131 2067664 IFLab1_003697 CC(C)c1cc(C(C)C)c(S(=O)NCCCN2CCOCC2)c(c1)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I02 compound treatment 0.342 0.0176 0.69 0.336 0.0105 0.22 0.6436 0.8882 2067665 IFLab1_003698 CC(C)n1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I03 compound treatment 0.347 0.0226 0.89 0.347 0.0215 0.45 0.9454 0.9505 1218592 IFLab1_003699 COc1ccc2cc(ccc2c1)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I04 compound treatment 0.266 -0.0584 -2.3 0.281 -0.0445 -0.93 -2.2832 -0.9209 2067666 IFLab1_003700 Brc1cccc(c1)S(=O)(=O)C=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I05 compound treatment 0.38 0.0556 2.18 0.366 0.0405 0.85 2.144 0.915 1119800 IFLab1_003701 CCC(=O)Nc1c2CSCc2nn1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I06 compound treatment 0.393 0.0686 2.7 0.408 0.0825 1.73 3.1269 0.9768 1216791 IFLab1_003702 C1CSC(N1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I07 compound treatment 0.354 0.0296 1.16 0.345 0.0195 0.41 1.1104 0.9014 1129857 IFLab1_003703 COC(=O)c1sc(cc1NC(=O)C2CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I08 compound treatment 0.353 0.0286 1.12 0.337 0.0115 0.24 0.9643 0.8396 1217935 IFLab1_003704 Cc1nc(cs1)c2cccc(N)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I09 compound treatment 0.343 0.0186 0.73 0.35 0.0245 0.51 0.8786 0.9851 2067667 IFLab1_003705 CCn1c(Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I10 compound treatment 0.348 0.0236 0.93 0.354 0.0285 0.6 1.0768 0.9773 1464364 IFLab1_003706 COC(=O)c1sc2ccccc2c1NC(=O)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I11 compound treatment 0.342 0.0176 0.69 0.332 0.0065 0.14 0.5845 0.8304 1535035 IFLab1_003707 CC(C)N(C(=O)Cn1c(C)nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I12 compound treatment 0.338 0.0136 0.53 0.341 0.0155 0.32 0.6064 0.9716 1073760 IFLab1_003708 COc1ccc(NC2=NCCS2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I13 compound treatment 0.342 0.0176 0.69 0.346 0.0205 0.43 0.7916 0.9738 2067668 IFLab1_003709 Cc1nnc(SCC(=O)Nc2ccccc2)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I14 compound treatment 0.339 0.0146 0.57 0.332 0.0065 0.14 0.501 0.8514 1344074 IFLab1_003710 CC(C)N(C(=O)Cn1c(=N)sc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I15 compound treatment 0.337 0.0126 0.49 0.317 -0.0085 -0.18 0.2235 0.4257 1379574 IFLab1_003711 CCOC(=O)CSc1nc2ccccc2c(=O)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I16 compound treatment 0.318 -0.00644 -0.25 0.326 5.0E-4 0.01 -0.1716 -0.6773 2067669 IFLab1_003712 Clc1ccccc1C(=O)Oc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I17 compound treatment 0.34 0.0156 0.61 0.338 0.0125 0.26 0.6176 0.9281 1735150 IFLab1_003713 N#CCc1ncc(CSc2nc3ccccc3[nH]2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I18 compound treatment 0.344 0.0196 0.77 0.339 0.0135 0.28 0.7436 0.9075 1013810 IFLab1_003714 O=C1OC2(CCCCC2)OC1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I19 compound treatment 0.348 0.0236 0.93 0.332 0.0065 0.14 0.7513 0.8023 1228915 IFLab1_003715 COc1cccc(OCC(=O)Nc2ccc(F)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I20 compound treatment 0.341 0.0166 0.65 0.372 0.0465 0.97 1.1485 0.9809 1248295 IFLab1_003716 CN(C)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I21 compound treatment 0.337 0.0126 0.49 0.346 0.0205 0.43 0.6526 0.9975 1296632 IFLab1_003717 OC(=O)CNC(=O)COc1cccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I22 compound treatment 0.335 0.0106 0.42 0.308 -0.0175 -0.37 0.0347 0.0627 2067670 IFLab1_003718 CN1CCN(CC1)c2cc(C)ncn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I23 mock treatment 0.33 0.00556 0.22 0.33 0.0045 0.09 0.2212 0.9291 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 I24 positive control 0.083 -0.241 -9.49 0.085 -0.24 -5.03 -10.2712 -0.956 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J01 compound treatment 0.337 0.0126 0.49 0.333 0.0075 0.16 0.4602 0.888 1357445 IFLab1_003719 CC1(C)COC(=O)C1OC(=O)c2ccccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J02 compound treatment 0.328 0.00356 0.14 0.329 0.0035 0.07 0.1508 0.9543 2067671 IFLab1_003720 CC(=C)C(=O)Oc1ccc(cc1)N2Cc3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J03 compound treatment 0.33 0.00556 0.22 0.322 -0.0035 -0.07 0.1029 0.446 1673475 IFLab1_003721 CCc1nc(c2ccccc2)c3ccccn13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J04 compound treatment 0.331 0.00656 0.26 0.325 -5.0E-4 -0.01 0.1751 0.6779 2067672 IFLab1_003722 CCc1nnc2SCC(=Nn12)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J05 compound treatment 0.341 0.0166 0.65 0.333 0.0075 0.16 0.5714 0.8531 2067673 IFLab1_003723 COC(=O)c1sc2ccccc2c1NC(=O)c3cc(Cl)sc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J06 compound treatment 0.358 0.0336 1.32 0.36 0.0345 0.72 1.4436 0.9597 2067674 IFLab1_003724 Fc1ccc(NC2=NC(=O)/C(=C\c3ccc4OCOc4c3)/S2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J07 compound treatment 0.334 0.00956 0.38 0.329 0.0035 0.07 0.3176 0.8293 1605554 IFLab1_003725 O=C(Nc1ccc2sccc2c1)c3cccc(c3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J08 compound treatment 0.337 0.0126 0.49 0.328 0.0025 0.05 0.3863 0.7777 1647947 IFLab1_003726 COc1cccc2sc(=NC(=O)c3ccc(C#N)cc3)n(C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J09 compound treatment 0.33 0.00556 0.22 0.329 0.0035 0.07 0.2064 0.8951 2067675 IFLab1_003727 OC(=O)c1ccccc1SCC(=O)Nc2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J10 compound treatment 0.34 0.0156 0.61 0.329 0.0035 0.07 0.4845 0.7861 1316524 IFLab1_003728 COC(=O)c1ccc(cc1)C(=O)N=c2sc3cc(F)ccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J11 compound treatment 0.947 0.623 24.48 0.955 0.629 13.17 26.6233 0.9578 2067676 IFLab1_003729 COc1ccc(NC(=O)CSC2=NCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J12 compound treatment 0.342 0.0176 0.69 0.326 5.0E-4 0.01 0.4957 0.7177 1447150 IFLab1_003730 COc1cc(C)c(cc1S(=O)(=O)N2CCCC(C)C2)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J13 compound treatment 0.448 0.124 4.86 0.413 0.0875 1.83 4.73 0.9111 2067677 IFLab1_003731 COc1ccc(/C=C/C(=O)Nc2sc3CCCCc3c2C(=O)N)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J14 compound treatment 0.342 0.0176 0.69 0.341 0.0155 0.32 0.7176 0.9406 1637379 IFLab1_003732 CCN1CCN(CC(O)COc2cccc(OC)c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J15 compound treatment 0.386 0.0616 2.42 0.387 0.0615 1.29 2.6216 0.9563 2067678 IFLab1_003733 Cc1ccc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)S(=O)(=O)N)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J16 compound treatment 0.351 0.0266 1.04 0.341 0.0155 0.32 0.9678 0.885 1303213 IFLab1_003734 CN1CCN(CC(O)COc2ccc(cc2)C3CCCCC3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J17 compound treatment 0.334 0.00956 0.38 0.342 0.0165 0.35 0.51 0.9991 1246133 IFLab1_003735 CCC(CO)Nc1nc(C)nc2sc3CCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J18 compound treatment 0.341 0.0166 0.65 0.341 0.0155 0.32 0.6898 0.9482 1283409 IFLab1_003736 CC1CCCCN1CC(O)COc2c(F)cc(Br)cc2F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J19 compound treatment 0.347 0.0226 0.89 0.335 0.0095 0.2 0.7679 0.8446 1562712 IFLab1_003737 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J20 compound treatment 0.342 0.0176 0.69 0.333 0.0075 0.16 0.5993 0.8462 2067679 IFLab1_003738 O=C/1Oc2ccccc2C(=O)\C1=C\NN3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J21 compound treatment 0.343 0.0186 0.73 0.343 0.0175 0.37 0.775 0.9491 1327796 IFLab1_003739 OC(=O)CCCN1C(=O)C2C3CC(C=C3)C2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J22 compound treatment 0.337 0.0126 0.49 0.337 0.0115 0.24 0.5194 0.9454 1421681 IFLab1_003740 OC(=O)C1CCN(CC1)S(=O)(=O)c2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J23 mock treatment 0.322 -0.00244 -0.1 0.326 5.0E-4 0.01 -0.0604 -0.6262 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 J24 positive control 0.084 -0.24 -9.45 0.086 -0.239 -5.01 -10.2286 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K01 compound treatment 0.334 0.00956 0.38 0.335 0.0095 0.2 0.4064 0.9556 1597075 IFLab1_003741 Cc1ccc(c(C)c1)S(=O)(=O)n2cnc3cc(C)c(C)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K02 compound treatment 0.336 0.0116 0.45 0.337 0.0115 0.24 0.4916 0.9558 2067680 IFLab1_003742 CCCn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K03 compound treatment 0.324 -4.37E-4 -0.02 0.314 -0.0115 -0.24 -0.1823 -0.7557 2067681 IFLab1_003743 Clc1ccc2n(nnc2c1)C(=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K04 compound treatment 0.376 0.0516 2.03 0.372 0.0465 0.97 2.1216 0.9435 1643138 IFLab1_003744 O=S1(=O)CCC(C1)NC(=S)SCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K05 compound treatment 0.365 0.0406 1.59 0.357 0.0315 0.66 1.5938 0.9236 1547490 IFLab1_003745 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K06 compound treatment 0.324 -4.37E-4 -0.02 0.342 0.0165 0.35 0.232 0.671 1294431 IFLab1_003746 COc1ccc(cc1)C2SCCN2S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K07 compound treatment 0.324 -4.37E-4 -0.02 0.339 0.0135 0.28 0.1876 0.6628 1655407 IFLab1_003747 COC(=O)c1sc(cc1NC(=O)C2CCCCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K08 compound treatment 0.348 0.0236 0.93 0.358 0.0325 0.68 1.136 0.9884 1583005 IFLab1_003748 COc1ccccc1C(=O)Nc2ccc(cc2)c3csc(C)n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K09 compound treatment 0.332 0.00756 0.3 0.329 0.0035 0.07 0.262 0.8557 2067682 IFLab1_003749 CCCCn1c(nc2ccccc12)C(C)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K10 compound treatment 0.351 0.0266 1.04 0.333 0.0075 0.16 0.8495 0.8043 1479098 IFLab1_003750 O=C(Nc1ncc(s1)c2ccccc2)c3cccc(c3)N4C(=O)CCC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K11 compound treatment 0.342 0.0176 0.69 0.344 0.0185 0.39 0.762 0.9626 1157513 IFLab1_003751 CC(C)N(C(=O)Cn1c(CO)nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K12 compound treatment 0.365 0.0406 1.59 0.359 0.0335 0.7 1.6234 0.9319 2067683 IFLab1_003752 CCOc1ccc(cc1)n2nnnc2SCC(=O)c3c(C)cc(C)cc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K13 compound treatment 0.356 0.0316 1.24 0.341 0.0155 0.32 1.1069 0.8629 1467007 IFLab1_003753 Cc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2C)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K14 compound treatment 0.345 0.0206 0.81 0.347 0.0215 0.45 0.8898 0.9617 2067684 IFLab1_003754 COc1ccc(NC(=O)CSc2nnc(C)n2c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K15 compound treatment 0.347 0.0226 0.89 0.348 0.0225 0.47 0.9602 0.9561 1301130 IFLab1_003755 O=C(CSc1nc2ccccc2c(=O)n1c3ccccc3)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K16 compound treatment 0.348 0.0236 0.93 0.348 0.0225 0.47 0.988 0.9507 1621327 IFLab1_003756 OC(=O)CC(NS(=O)(=O)c1ccc(Br)cc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K17 compound treatment 0.343 0.0186 0.73 0.345 0.0195 0.41 0.8046 0.9623 1550526 IFLab1_003757 O=C(N1CCCC1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K18 compound treatment 0.341 0.0166 0.65 0.345 0.0195 0.41 0.749 0.9747 1036303 IFLab1_003758 COc1ccc(NS(=O)(=O)c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K19 compound treatment 0.346 0.0216 0.85 0.323 -0.0025 -0.05 0.5625 0.6622 1138357 IFLab1_003759 Cc1ccc(Oc2ccc(OCC(=O)NCC3CCCO3)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K20 compound treatment 0.387 0.0626 2.46 0.376 0.0505 1.06 2.4866 0.9288 1260052 IFLab1_003760 CC1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K21 compound treatment 0.347 0.0226 0.89 0.326 5.0E-4 0.01 0.6347 0.7154 1661854 IFLab1_003761 OCCSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K22 compound treatment 0.343 0.0186 0.73 0.339 0.0135 0.28 0.7158 0.9147 1442345 IFLab1_003762 CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K23 mock treatment 0.322 -0.00244 -0.1 0.323 -0.0025 -0.05 -0.1048 -0.9595 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 K24 positive control 0.085 -0.239 -9.41 0.087 -0.238 -4.99 -10.186 -0.9559 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L01 compound treatment 0.338 0.0136 0.53 0.333 0.0075 0.16 0.488 0.878 1421062 IFLab1_003763 CCN1CCN(Cc2oc(CO)cc(=O)c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L02 compound treatment 0.317 -0.00744 -0.29 0.315 -0.0105 -0.22 -0.3621 -0.9901 1742285 IFLab1_003764 CC(=O)Oc1cccc(c1)N2Cc3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L03 compound treatment 0.346 0.0216 0.85 0.322 -0.0035 -0.07 0.5477 0.6436 1590090 IFLab1_003765 COc1cccc2cc(c3nc4ccccc4s3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L04 compound treatment 0.319 -0.00544 -0.21 0.323 -0.0025 -0.05 -0.1882 -0.8549 2067685 IFLab1_003766 FC(F)(F)c1nnc2SCC(=Nn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L05 compound treatment 0.324 -4.37E-4 -0.02 0.327 0.0015 0.03 0.01 0.2803 1623297 IFLab1_003767 O=C(Nc1ccc2sccc2c1)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L06 compound treatment 0.327 0.00256 0.1 0.334 0.0085 0.18 0.197 0.9638 2067686 IFLab1_003768 Oc1ccc(/C=C\2/SC(=NC2=O)Nc3cccnc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L07 compound treatment 0.344 0.0196 0.77 0.338 0.0125 0.26 0.7288 0.8971 2067687 IFLab1_003769 COC(=O)c1ccc(cc1)C(=O)Nc2ccc3sccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L08 compound treatment 0.343 0.0186 0.73 0.346 0.0205 0.43 0.8194 0.9679 1691783 IFLab1_003770 NC(=O)c1oc2ccccc2c1NC(=O)Cc3cccc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L09 compound treatment 0.34 0.0156 0.61 0.363 0.0375 0.78 0.9876 0.9924 1429998 IFLab1_003771 Cc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L10 compound treatment 0.32 -0.00444 -0.17 0.346 0.0205 0.43 0.18 0.3886 1920805 IFLab1_003772 CCOC(=O)CSc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L11 compound treatment 0.339 0.0146 0.57 0.344 0.0185 0.39 0.6786 0.9818 1481544 IFLab1_003773 Brc1ccc(OCc2nnc3CCCCCn23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L12 compound treatment 0.326 0.00156 0.06 0.337 0.0115 0.24 0.2136 0.86 1230624 IFLab1_003774 CC1CN(CCN1C(=O)c2cccs2)C(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L13 compound treatment 0.332 0.00756 0.3 0.348 0.0225 0.47 0.5432 0.9754 2067688 IFLab1_003775 Cc1noc(C)c1CSc2ncnc3sc4CCCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L14 compound treatment 0.341 0.0166 0.65 0.342 0.0165 0.35 0.7046 0.956 1568403 IFLab1_003776 COc1cccc(OCC(O)CN2CCN(CC2)c3ccc(F)cc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L15 compound treatment 0.289 -0.0354 -1.39 0.327 0.0015 0.03 -0.963 -0.691 2067689 IFLab1_003777 NS(=O)(=O)c1ccc(cc1)N2C(=O)/C(=C\C=C\c3ccccc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L16 compound treatment 0.339 0.0146 0.57 0.338 0.0125 0.26 0.5898 0.937 1585215 IFLab1_003778 CCN1CCN(CC(O)COc2ccc(cc2)C3CCCCC3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L17 compound treatment 0.34 0.0156 0.61 0.342 0.0165 0.35 0.6768 0.9633 2067690 IFLab1_003779 Cc1sc2ncnc(Sc3ccccc3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L18 compound treatment 0.342 0.0176 0.69 0.335 0.0095 0.2 0.6288 0.8751 1457194 IFLab1_003780 CC1CCCCN1CC(O)COc2cc(C)c(Cl)c(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L19 compound treatment 0.345 0.0206 0.81 0.339 0.0135 0.28 0.7714 0.9008 1396726 IFLab1_003781 CC(C)CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L20 compound treatment 0.364 0.0396 1.56 0.36 0.0345 0.72 1.6104 0.9391 2067691 IFLab1_003782 COc1ccc(N/C=C/2\C(=O)OC(=CC2=O)C)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L21 compound treatment 0.344 0.0196 0.77 0.336 0.0105 0.22 0.6992 0.8741 1156241 IFLab1_003783 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L22 compound treatment 0.349 0.0246 0.97 0.354 0.0285 0.6 1.1046 0.9732 1271483 IFLab1_003784 Fc1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L23 mock treatment 0.328 0.00356 0.14 0.327 0.0015 0.03 0.1212 0.8446 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 L24 positive control 0.085 -0.239 -9.41 0.088 -0.237 -4.97 -10.1712 -0.9554 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M01 compound treatment 0.335 0.0106 0.42 0.327 0.0015 0.03 0.3159 0.7584 1722879 IFLab1_003785 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M02 compound treatment 0.317 -0.00744 -0.29 0.317 -0.0085 -0.18 -0.3326 -0.9716 2067692 IFLab1_003786 CC(C)Cn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M03 compound treatment 0.301 -0.0234 -0.92 0.31 -0.0155 -0.32 -0.881 -0.9018 1334268 IFLab1_003787 COc1ccc(OC)c(c1)S(=O)(=O)N2C(C)CCCC2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M04 compound treatment 0.321 -0.00344 -0.14 0.324 -0.0015 -0.03 -0.1178 -0.8487 1337692 IFLab1_003788 O=C(NC1CS(=O)(=O)C=C1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M05 compound treatment 0.399 0.0746 2.93 0.403 0.0775 1.62 3.2198 0.961 1555709 IFLab1_003789 Cc1cc(C)cc(c1)n2nc3CSCc3c2NC(=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M06 compound treatment 0.306 -0.0184 -0.72 0.306 -0.0195 -0.41 -0.8011 -0.963 1577333 IFLab1_003790 OCCNC(=O)c1cc2cc(Br)ccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M07 compound treatment 0.392 0.0676 2.66 0.385 0.0595 1.25 2.7588 0.9404 1552568 IFLab1_003791 O=C(Cc1ccccc1)Nc2nc(cs2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M08 compound treatment 0.314 -0.0104 -0.41 0.356 0.0305 0.64 0.1611 0.2123 1670918 IFLab1_003792 Cc1nc(sc1C(=O)Nc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M09 compound treatment 0.334 0.00956 0.38 0.339 0.0135 0.28 0.4656 0.9901 1030469 IFLab1_003793 CC(O)c1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M10 compound treatment 0.336 0.0116 0.45 0.344 0.0185 0.39 0.5952 0.9968 1299003 IFLab1_003794 CCC(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M11 compound treatment 0.339 0.0146 0.57 0.348 0.0225 0.47 0.7378 0.9953 1699317 IFLab1_003795 CC(C)N(C(=O)Cn1c(nc2ccccc12)C(C)O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M12 compound treatment 0.341 0.0166 0.65 0.353 0.0275 0.58 0.8674 0.9981 1504395 IFLab1_003796 CC(C)N(C(=O)CSc1nc2ccccc2[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M13 compound treatment 0.348 0.0236 0.93 0.364 0.0385 0.81 1.2248 0.9976 2067693 IFLab1_003797 CCOc1ccc(cc1)C(=O)CSc2nnc(CC)n2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M14 compound treatment 0.344 0.0196 0.77 0.342 0.0165 0.35 0.788 0.9347 2067694 IFLab1_003798 c1csc(c1)c2cn3ccsc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M15 compound treatment 0.336 0.0116 0.45 0.344 0.0185 0.39 0.5952 0.9968 1406732 IFLab1_003799 OC(=O)c1ccc(CSc2nc3ccccc3s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M16 compound treatment 0.334 0.00956 0.38 0.325 -5.0E-4 -0.01 0.2585 0.6872 1032066 IFLab1_003800 Cc1ccccc1NS(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M17 compound treatment 0.36 0.0356 1.4 0.357 0.0315 0.66 1.4548 0.9411 2067695 IFLab1_003801 Cc1ccc(cc1)C(=O)CSc2nnnn2c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M18 compound treatment 0.313 -0.0114 -0.45 0.346 0.0205 0.43 -0.0146 -0.0236 1463364 IFLab1_003802 CCOc1ccc(cc1)S(=O)(=O)N2CCC(C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M19 compound treatment 0.319 -0.00544 -0.21 0.333 0.0075 0.16 -0.0402 -0.1516 1369379 IFLab1_003803 CC1CCCC(C)N1C(=O)COc2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M20 compound treatment 0.171 -0.153 -6.03 0.159 -0.167 -3.48 -6.7296 -0.966 1641505 IFLab1_003804 CCOc1ccc(cc1)S(=O)(=O)Nc2cc(Cl)c(O)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M21 compound treatment 0.306 -0.0184 -0.72 0.306 -0.0195 -0.41 -0.8011 -0.963 2067696 IFLab1_003805 CN(C)c1nc(c2ccccc2)c3cc(Cl)ccc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M22 compound treatment 0.348 0.0236 0.93 0.345 0.0195 0.41 0.9436 0.9321 2067697 IFLab1_003806 COC(=O)CN1CCN(CC1)S(=O)(=O)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M23 mock treatment 0.327 0.00256 0.1 0.332 0.0065 0.14 0.1674 0.9891 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 M24 positive control 0.087 -0.237 -9.34 0.091 -0.234 -4.91 -10.0712 -0.9549 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N01 compound treatment 0.333 0.00856 0.34 0.328 0.0025 0.05 0.275 0.8073 1262773 IFLab1_003807 OC(c1ccc2OCOc2c1)c3nccc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N02 compound treatment 0.367 0.0426 1.67 0.369 0.0435 0.91 1.827 0.959 2067698 IFLab1_003808 COC(=O)c1ccc(NC(=O)CSC2=NCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N03 compound treatment 0.306 -0.0184 -0.72 0.297 -0.0285 -0.6 -0.9343 -0.9953 1162882 IFLab1_003809 Cc1[nH]c2ccccc2c1C(N3CCOCC3)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N04 compound treatment 0.32 -0.00444 -0.17 0.322 -0.0035 -0.07 -0.1752 -0.9257 1283766 IFLab1_003810 Cc1n[nH]c(O)c1C2=NCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N05 compound treatment 0.326 0.00156 0.06 0.33 0.0045 0.09 0.11 0.9786 2067699 IFLab1_003811 O=C(Nc1ccc2sccc2c1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N06 compound treatment 0.331 0.00656 0.26 0.329 0.0035 0.07 0.2342 0.8733 2067700 IFLab1_003812 COC(=O)c1ccc(/C=C\2/SC(=NC2=O)Nc3cccnc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N07 compound treatment 0.378 0.0536 2.11 0.361 0.0355 0.74 2.0144 0.9021 1237264 IFLab1_003813 CSc1nc2ccc3nc(N)sc3c2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N08 compound treatment 0.341 0.0166 0.65 0.341 0.0155 0.32 0.6898 0.9482 1137905 IFLab1_003814 Cc1ccc2n(C)c(=NC(=O)Cc3cccc4ccccc34)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N09 compound treatment 0.338 0.0136 0.53 0.335 0.0095 0.2 0.5176 0.9096 1632673 IFLab1_003815 CC(=O)Nc1ccc(cc1)c2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N10 compound treatment 0.34 0.0156 0.61 0.341 0.0155 0.32 0.662 0.9559 2067701 IFLab1_003816 Cc1ccc(N/C=C(\C#N)/c2nc(cs2)c3cc4ccccc4oc3=O)cc1F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N11 compound treatment 0.348 0.0236 0.93 0.327 0.0015 0.03 0.6773 0.7306 1475279 IFLab1_003817 CCc1ccc(cc1)C(=O)CSc2ccccc2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N12 compound treatment 0.346 0.0216 0.85 0.344 0.0185 0.39 0.8732 0.9369 1242387 IFLab1_003818 Cc1cccc(c1)C(=O)N2CCCN(CC2)C(=O)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N13 compound treatment 0.348 0.0236 0.93 0.346 0.0205 0.43 0.9584 0.9388 2067702 IFLab1_003819 Cc1sc2ncnc(Sc3nnnn3c4ccccc4)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N14 compound treatment 0.331 0.00656 0.26 0.343 0.0175 0.37 0.4414 0.9853 1370244 IFLab1_003820 COc1cccc(OCC(O)CN2CCc3ccccc3C2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N15 compound treatment 0.753 0.429 16.85 0.747 0.421 8.82 18.1519 0.9544 2067703 IFLab1_003821 OC(=O)COc1ccccc1/C=C\2/SC(=S)N(C2=O)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N16 compound treatment 0.336 0.0116 0.45 0.303 -0.0225 -0.47 -0.0115 -0.0175 1541183 IFLab1_003822 CC1CN(CC(O)COc2ccc(cc2)C3CCCCC3)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N17 compound treatment 0.334 0.00956 0.38 0.336 0.0105 0.22 0.4212 0.9673 1214816 IFLab1_003823 NC(=O)CCS(=O)(=O)CCN1CCCCC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N18 compound treatment 0.383 0.0586 2.3 0.371 0.0455 0.95 2.3014 0.9237 1663477 IFLab1_003824 Oc1ccccc1C(Nc2nccs2)c3ccc4cccnc4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N19 compound treatment 0.345 0.0206 0.81 0.336 0.0105 0.22 0.727 0.8678 2067704 IFLab1_003825 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N20 compound treatment 0.353 0.0286 1.12 0.351 0.0255 0.53 1.1714 0.9421 2067705 IFLab1_003826 Clc1ccc(SCc2cn3cccnc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N21 compound treatment 0.344 0.0196 0.77 0.333 0.0075 0.16 0.6549 0.8342 1043174 IFLab1_003827 O=C1C2C3CC(C=C3)C2C(=O)N1c4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N22 compound treatment 0.342 0.0176 0.69 0.338 0.0125 0.26 0.6732 0.9117 2067706 IFLab1_003828 CC1CCN(CC1)S(=O)(=O)c2ccc(/C=C/C(=O)O)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N23 mock treatment 0.328 0.00356 0.14 0.328 0.0025 0.05 0.136 0.9098 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 N24 positive control 0.092 -0.232 -9.14 0.091 -0.234 -4.91 -9.9322 -0.9575 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O01 compound treatment 0.331 0.00656 0.26 0.319 -0.0065 -0.14 0.0863 0.2958 1377919 IFLab1_003829 COc1ccc(Cl)cc1S(=O)(=O)N2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O02 compound treatment 0.313 -0.0114 -0.45 0.315 -0.0105 -0.22 -0.4734 -0.9457 2899 IFLab1_003830 COc1ccc(cc1)c2noc(CC(=O)O)c2c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O03 compound treatment 0.333 0.00856 0.34 0.326 5.0E-4 0.01 0.2455 0.7287 1434813 IFLab1_003831 CC1CN(CCN1S(=O)(=O)c2ccc(Cl)cc2)S(=O)(=O)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O04 compound treatment 0.314 -0.0104 -0.41 0.317 -0.0085 -0.18 -0.416 -0.93 1487527 IFLab1_003832 Cc1ccc(Nc2nnc(s2)c3cc4cc(Cl)ccc4oc3=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O05 compound treatment 0.316 -0.00844 -0.33 0.312 -0.0135 -0.28 -0.4343 -0.9968 1266519 IFLab1_003833 CC(=O)Nc1ccncc1NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O06 compound treatment 0.329 0.00456 0.18 0.327 0.0015 0.03 0.149 0.8184 1565108 IFLab1_003834 COc1ccccc1C2SCCN2S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O07 compound treatment 0.334 0.00956 0.38 0.33 0.0045 0.09 0.3324 0.8577 1321850 IFLab1_003835 CCc1cccc(CC)c1N(COC)C(=O)Cn2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O08 compound treatment 0.384 0.0596 2.34 0.373 0.0475 0.99 2.3588 0.9272 2067707 IFLab1_003836 Cc1nc(cs1)c2cccc(NC(=O)/C=C\C(=O)O)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O09 compound treatment 0.32 -0.00444 -0.17 0.327 0.0015 0.03 -0.1012 -0.5707 1033879 IFLab1_003837 C(Oc1ccccc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O10 compound treatment 0.327 0.00256 0.1 0.344 0.0185 0.39 0.345 0.8624 1381079 IFLab1_003838 CCC(=O)Nc1sc2CCCCCc2c1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O11 compound treatment 0.363 0.0386 1.52 0.371 0.0455 0.95 1.7454 0.9749 1281502 IFLab1_003839 CC(C)C(=O)Nc1ccc(cc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O12 compound treatment 0.339 0.0146 0.57 0.401 0.0755 1.58 1.522 0.9057 2067708 IFLab1_003840 C1CN=C(C1)NC2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O13 compound treatment 0.338 0.0136 0.53 0.334 0.0085 0.18 0.5028 0.8945 1232395 IFLab1_003841 C=CCn1nnnc1SCC(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O14 compound treatment 0.366 0.0416 1.63 0.358 0.0325 0.68 1.6364 0.9245 1684284 IFLab1_003842 OC(=O)CN1C(=O)c2cccc3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O15 compound treatment 0.361 0.0366 1.44 0.363 0.0375 0.78 1.5714 0.9595 2067709 IFLab1_003843 CN(C1=CC(=O)c2ccccc2C1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O16 compound treatment 0.348 0.0236 0.93 0.348 0.0225 0.47 0.988 0.9507 1232143 IFLab1_003844 Cc1ccc(C)c(c1)S(=O)(=O)Nc2ccc(O)c(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O17 compound treatment 0.343 0.0186 0.73 0.341 0.0155 0.32 0.7454 0.9333 1556147 IFLab1_003845 CCc1ccc(cc1)c2csc(N)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O18 compound treatment 0.344 0.0196 0.77 0.338 0.0125 0.26 0.7288 0.8971 2067710 IFLab1_003846 CCOc1ccc(cc1)S(=O)(=O)NC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O19 compound treatment 0.341 0.0166 0.65 0.335 0.0095 0.2 0.601 0.8828 1143616 IFLab1_003847 CN(C1CCS(=O)(=O)C1)C(=O)COc2cccc(Br)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O20 compound treatment 0.368 0.0436 1.71 0.365 0.0395 0.83 1.7956 0.9442 1687160 IFLab1_003848 NS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O21 compound treatment 0.343 0.0186 0.73 0.35 0.0245 0.51 0.8786 0.9851 1208892 IFLab1_003849 CCC(Sc1ccc(Cl)cc1)C(=O)Nc2nnc(s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O22 compound treatment 0.341 0.0166 0.65 0.341 0.0155 0.32 0.6898 0.9482 2067711 IFLab1_003850 COC(=O)CSc1nnc(SCc2ccc(Cl)cc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O23 mock treatment 0.324 -4.37E-4 -0.02 0.331 0.0055 0.12 0.0692 0.5948 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 O24 positive control 0.091 -0.233 -9.18 0.096 -0.23 -4.8 -9.886 -0.9543 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P01 compound treatment 0.355 0.0306 1.2 0.36 0.0345 0.72 1.3602 0.9703 1460909 IFLab1_003851 OCCN1CCN(CC1)C(c2ccccc2)c3ccc4cccnc4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P02 compound treatment 0.446 0.122 4.78 0.456 0.131 2.73 5.3107 0.9648 2067712 IFLab1_003852 Cc1ccc(NC(=O)CSC2=NCCN2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P03 compound treatment 0.344 0.0196 0.77 0.335 0.0095 0.2 0.6844 0.8616 1584511 IFLab1_003853 Cc1ccc(o1)c2csc(NC(=O)c3nc4ccccc4s3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P04 compound treatment 0.352 0.0276 1.08 0.343 0.0175 0.37 1.0252 0.8963 2067713 IFLab1_003854 Cc1n[nH]c(O)c1C2=NCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P05 compound treatment 0.362 0.0376 1.48 0.361 0.0355 0.74 1.5696 0.9494 2067714 IFLab1_003855 O=C(Nc1ccc2sccc2c1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P06 compound treatment 0.375 0.0506 1.99 0.359 0.0335 0.7 1.9014 0.902 2067715 IFLab1_003856 O=C/1N=C(Nc2cccnc2)S\C1=C\c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P07 compound treatment 0.371 0.0466 1.83 0.36 0.0345 0.72 1.805 0.9172 1685961 IFLab1_003857 CCC(=O)Nc1nc2ccc3nc(SC)sc3c2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P08 compound treatment 0.478 0.154 6.04 0.465 0.14 2.92 6.3335 0.9444 1504525 IFLab1_003858 NC(=O)c1oc2ccccc2c1NC(=O)C(c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P09 compound treatment 0.368 0.0436 1.71 0.373 0.0475 0.99 1.914 0.9665 2067716 IFLab1_003859 CCCc1nnc(SCC(=O)O)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P10 compound treatment 0.428 0.104 4.07 0.435 0.11 2.29 4.4995 0.963 2067717 IFLab1_003860 NC(=O)c1ccc(N/C=C(\C#N)/c2nc(cs2)c3cccc(Br)c3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P11 compound treatment 0.369 0.0446 1.75 0.374 0.0485 1.01 1.9566 0.9663 1312456 IFLab1_003861 COC(=O)c1ccc(NCC(=O)c2ccc(OC)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P12 compound treatment 0.367 0.0426 1.67 0.372 0.0465 0.97 1.8714 0.9667 1298903 IFLab1_003862 Cc1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P13 compound treatment 0.387 0.0626 2.46 0.382 0.0565 1.18 2.5754 0.9436 1591687 IFLab1_003863 CC1CCc2c(C(=O)O)c(NC(=O)c3cccs3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P14 compound treatment 0.375 0.0506 1.99 0.374 0.0485 1.01 2.1234 0.9513 1199813 IFLab1_003864 COc1cccc(OCC(O)CNC(C)c2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P15 compound treatment 0.534 0.21 8.24 0.542 0.217 4.53 9.0298 0.9603 2067718 IFLab1_003865 OC(=O)COc1ccccc1/C=C\2/SC(=S)N(Cc3ccco3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P16 compound treatment 0.376 0.0516 2.03 0.381 0.0555 1.16 2.2548 0.965 1241600 IFLab1_003866 OC(COc1ccc(cc1)C2CCCCC2)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P17 compound treatment 0.379 0.0546 2.15 0.372 0.0465 0.97 2.205 0.936 2067719 IFLab1_003867 Cc1ccc(cc1)N(Sc2ccc(Cl)cc2)C3CS(=O)(=O)C=C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P18 compound treatment 0.44 0.116 4.54 0.433 0.108 2.25 4.8036 0.9474 1368925 IFLab1_003868 Oc1c(ccc2cccnc12)C(Nc3nccs3)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P19 compound treatment 0.362 0.0376 1.48 0.352 0.0265 0.55 1.4364 0.9105 1589801 IFLab1_003869 CCOc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P20 compound treatment 0.356 0.0316 1.24 0.355 0.0295 0.62 1.314 0.948 1522937 IFLab1_003870 O=C1CC(Sc2nc3ccccc3n12)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P21 compound treatment 0.363 0.0386 1.52 0.354 0.0285 0.6 1.4938 0.9169 2067720 IFLab1_003871 CC(=C)C(=O)Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P22 compound treatment 0.338 0.0136 0.53 0.355 0.0295 0.62 0.8136 0.9973 1429354 IFLab1_003872 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P23 mock treatment 0.329 0.00456 0.18 0.328 0.0025 0.05 0.1638 0.8768 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1422 P24 positive control 0.094 -0.23 -9.06 0.099 -0.227 -4.74 -9.7582 -0.9543 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A01 compound treatment 0.336 0.0111 0.43 0.343 0.0178 0.37 0.5711 0.997 2067721 IFLab1_003873 O=S(=O)(/C=C/c1ccccc1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A02 compound treatment 0.33 0.00506 0.2 0.327 0.00181 0.04 0.1676 0.827 1694079 IFLab1_003874 OC(CC(=O)O)c1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A03 compound treatment 0.315 -0.00994 -0.39 0.328 0.00281 0.06 -0.2347 -0.5939 2067722 IFLab1_003875 CCOC(=O)c1oc2ccccc2c1NC(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A04 compound treatment 0.357 0.0321 1.26 0.327 0.00181 0.04 0.9182 0.7281 2067723 IFLab1_003876 CC(C)c1nc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A05 compound treatment 0.337 0.0121 0.47 0.325 -1.88E-4 0.0 0.3326 0.7012 2067724 IFLab1_003877 Cc1ccc2cc(/N=C/c3ccc(O)cc3)ccc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A06 compound treatment 0.325 6.25E-5 0.0 0.355 0.0298 0.62 0.4429 0.7099 1310560 IFLab1_003878 COc1ccc(cc1OC)c2nc3ccccc3n2C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A07 compound treatment 0.317 -0.00794 -0.31 0.333 0.00781 0.16 -0.1051 -0.2982 1559622 IFLab1_003879 CC1(C)C2(C)CCC1(CC2=O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A08 compound treatment 0.345 0.0201 0.79 0.328 0.00281 0.06 0.5994 0.7578 1249669 IFLab1_003880 CCN(CC)Cc1cc(C(C)C)c(O)c(c1)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A09 compound treatment 0.324 -9.37E-4 -0.04 0.323 -0.00219 -0.05 -0.0584 -0.9942 1210566 IFLab1_003881 CC1(C)C2CCC1(C)C(C2)NC(=O)CCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A10 compound treatment 0.351 0.0261 1.02 0.377 0.0518 1.08 1.4913 0.9996 2067725 IFLab1_003882 CC(=O)Nc1ccc(/N=C/c2ccc(OC(=O)c3ccccc3Br)cc2O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A11 compound treatment 0.364 0.0391 1.54 0.365 0.0398 0.83 1.6751 0.9587 2067726 IFLab1_003883 NC(=O)/C(=N\O)/c1nc(cs1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A12 compound treatment 0.352 0.0271 1.06 0.328 0.00281 0.06 0.794 0.7451 2067727 IFLab1_003884 COc1ccc(cc1)n2ccsc2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A13 compound treatment 0.331 0.00606 0.24 0.313 -0.0122 -0.26 -0.0118 -0.0338 2067728 IFLab1_003885 COc1ccc2nc(sc2c1)/C(=N/O)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A14 compound treatment 0.318 -0.00694 -0.27 0.353 0.0278 0.58 0.2187 0.3402 1451497 IFLab1_003886 CC(=O)Nc1ccc(cc1)n2c(C)csc2=NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A15 compound treatment 0.328 0.00306 0.12 0.313 -0.0122 -0.26 -0.0952 -0.3375 2067729 IFLab1_003887 COc1ccc2cc(Br)ccc2c1CCl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A16 compound treatment 0.347 0.0221 0.87 0.315 -0.0102 -0.21 0.4626 0.5179 2067730 IFLab1_003888 Cc1sc(N2C(=O)C3C4CC(C=C4)C3C2=O)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A17 compound treatment 0.333 0.00806 0.32 0.337 0.0118 0.25 0.3989 0.9924 1009444 IFLab1_003889 CCn1c2ccccc2c3cc(N)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A18 compound treatment 0.324 -9.37E-4 -0.04 0.34 0.0148 0.31 0.1931 0.6187 2067731 IFLab1_003890 CC1(C)COC(=O)C1OC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A19 compound treatment 0.346 0.0211 0.83 0.327 0.00181 0.04 0.6124 0.7387 1774948 IFLab1_003891 NC(=O)c1cc(Cl)c([nH]c1=O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A20 compound treatment 0.329 0.00406 0.16 0.332 0.00681 0.14 0.2138 0.9984 2067732 IFLab1_003892 Cc1ccc(cc1)C(=O)CC(c2ccco2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A21 compound treatment 0.319 -0.00594 -0.23 0.341 0.0158 0.33 0.0689 0.1702 2067733 IFLab1_003893 C(c1ccccc1)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A22 compound treatment 0.325 6.25E-5 0.0 0.32 -0.00519 -0.11 -0.075 -0.6909 2067734 IFLab1_003894 O=c1[nH]c(nc2ccccc12)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A23 mock treatment 0.348 0.0231 0.91 0.318 -0.00719 -0.15 0.5348 0.5819 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 A24 positive control 0.079 -0.246 -9.67 0.079 -0.246 -5.15 -10.4804 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B01 compound treatment 0.35 0.0251 0.99 0.337 0.0118 0.25 0.8716 0.8579 2067735 IFLab1_003895 COc1ccccc1Oc2ncnc3scc(c4ccc(F)cc4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B02 compound treatment 0.329 0.00406 0.16 0.322 -0.00319 -0.07 0.0658 0.38 1464339 IFLab1_003896 Cc1sc2nc(SCC(=O)NC3CCCCC3)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B03 compound treatment 0.321 -0.00394 -0.15 0.323 -0.00219 -0.05 -0.1418 -0.8786 1493334 IFLab1_003897 CC1CN(CCC(=O)Nc2sc3CCCc3c2C#N)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B04 compound treatment 0.329 0.00406 0.16 0.34 0.0148 0.31 0.3321 0.9525 1584044 IFLab1_003898 Cc1ccc(o1)c2csc(NC(=O)c3coc4ccccc4c3=O)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B05 compound treatment 0.32 -0.00494 -0.19 0.317 -0.00819 -0.17 -0.2584 -0.9981 1391072 IFLab1_003899 COC(=O)c1ccc(OCc2c(C)noc2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B06 compound treatment 0.323 -0.00194 -0.08 0.337 0.0118 0.25 0.1209 0.4675 2067736 IFLab1_003900 O=C(OCc1nc2ccccc2s1)c3coc4ccccc4c3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B07 compound treatment 0.353 0.0281 1.1 0.332 0.00681 0.14 0.881 0.7919 1327211 IFLab1_003901 Fc1ccc2nc(NC(=O)CCc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B08 compound treatment 0.326 0.00106 0.04 0.33 0.00481 0.1 0.1008 0.9241 1687858 IFLab1_003902 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B09 compound treatment 0.332 0.00706 0.28 0.342 0.0168 0.35 0.4451 0.9931 1645978 IFLab1_003903 CCC(=O)Nc1nc(cs1)c2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B10 compound treatment 0.325 6.25E-5 0.0 0.328 0.00281 0.06 0.0434 0.736 1246329 IFLab1_003904 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B11 compound treatment 0.35 0.0251 0.99 0.349 0.0238 0.5 1.0491 0.9501 2067737 IFLab1_003905 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B12 compound treatment 0.336 0.0111 0.43 0.338 0.0128 0.27 0.4971 0.973 1702041 IFLab1_003906 CC(=C)CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B13 compound treatment 0.319 -0.00594 -0.23 0.334 0.00881 0.18 -0.0347 -0.1166 1416302 IFLab1_003907 O=C1CCCc2c1cc(c3ccccc3)n2c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B14 compound treatment 0.324 -9.37E-4 -0.04 0.339 0.0138 0.29 0.1783 0.612 2067738 IFLab1_003908 CC(C)CC1C(=C(N)OC2=C1C(=O)CCC2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B15 compound treatment 0.353 0.0281 1.1 0.342 0.0168 0.35 1.029 0.8885 1565528 IFLab1_003909 Oc1c(CN2CCCC2)cc(Cl)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B16 compound treatment 0.333 0.00806 0.32 0.337 0.0118 0.25 0.3989 0.9924 2067739 IFLab1_003910 Cc1cc(C)c(C#N)c(SCC(=O)Nc2nccs2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B17 compound treatment 0.335 0.0101 0.4 0.344 0.0188 0.39 0.5581 1.0 1411855 IFLab1_003911 OC(COc1ccc(F)cc1)CN2CCN(CC2)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B18 compound treatment 0.341 0.0161 0.63 0.339 0.0138 0.29 0.651 0.9372 2067740 IFLab1_003912 CCOC(=O)Cc1nc(cs1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B19 compound treatment 0.323 -0.00194 -0.08 0.326 8.12E-4 0.02 -0.0418 -0.5361 1234418 IFLab1_003913 CC(C)(C)c1ccccc1OCC(O)CN2CCN(CC2)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B20 compound treatment 0.336 0.0111 0.43 0.337 0.0118 0.25 0.4824 0.9641 1017621 IFLab1_003914 N#CC(CCN1CCOCC1)(c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B21 compound treatment 0.359 0.0341 1.34 0.364 0.0388 0.81 1.5213 0.9713 1985493 IFLab1_003915 CCOC(=O)CSc1nc(N)c2c3CCCCc3sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B22 compound treatment 0.332 0.00706 0.28 0.346 0.0208 0.44 0.5043 0.9764 1638899 IFLab1_003916 N#CC(N1CCOCC1)c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B23 mock treatment 0.327 0.00206 0.08 0.325 -1.88E-4 0.0 0.0546 0.6721 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 B24 positive control 0.078 -0.247 -9.71 0.078 -0.247 -5.17 -10.523 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C01 compound treatment 0.344 0.0191 0.75 0.343 0.0178 0.37 0.7935 0.948 2067741 IFLab1_003917 O=S(=O)(/C=C/c1ccccc1)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C02 compound treatment 0.332 0.00706 0.28 0.324 -0.00119 -0.02 0.1788 0.6413 1197757 IFLab1_003918 OC(C(O)c1nc2ccccc2[nH]1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C03 compound treatment 0.345 0.0201 0.79 0.341 0.0158 0.33 0.7918 0.9256 1475911 IFLab1_003919 O=C(Nc1ccccc1c2nc3ccccc3o2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C04 compound treatment 0.311 -0.0139 -0.55 0.341 0.0158 0.33 -0.1535 -0.2398 2067742 IFLab1_003920 CCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C05 compound treatment 0.329 0.00406 0.16 0.318 -0.00719 -0.15 0.0066 0.03 2067743 IFLab1_003921 CCOC(=O)c1ccc(/N=C/c2ccc(OC(=O)c3ccco3)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C06 compound treatment 0.335 0.0101 0.4 0.338 0.0128 0.27 0.4693 0.982 1064752 IFLab1_003922 Brc1cccc(c1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C07 compound treatment 0.338 0.0131 0.51 0.335 0.00981 0.21 0.5084 0.9191 2067744 IFLab1_003923 CN(C)C(=O)C1(CCC2(C)C(=O)C1)C2(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C08 compound treatment 0.339 0.0141 0.55 0.342 0.0168 0.35 0.6397 0.9762 1126912 IFLab1_003924 Cc1ccccc1NC(=O)Cn2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C09 compound treatment 0.329 0.00406 0.16 0.332 0.00681 0.14 0.2138 0.9984 1549344 IFLab1_003925 CC12COC3(CN)CC2CCC13C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C10 compound treatment 0.342 0.0171 0.67 0.335 0.00981 0.21 0.6196 0.8831 1736585 IFLab1_003926 NC(=O)CCSc1nnc(SCC(=O)c2ccccc2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C11 compound treatment 0.343 0.0181 0.71 0.343 0.0178 0.37 0.7657 0.9547 2067745 IFLab1_003927 O/N=C(\C#N)/c1nc(cs1)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C12 compound treatment 0.335 0.0101 0.4 0.339 0.0138 0.29 0.4841 0.9881 1533408 IFLab1_003928 CCOC(=O)c1sc(=S)n(c1C)c2ccc(OC)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C13 compound treatment 0.336 0.0111 0.43 0.335 0.00981 0.21 0.4528 0.9413 2067746 IFLab1_003929 CNc1ccc2ccccc2c1SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C14 compound treatment 0.33 0.00506 0.2 0.332 0.00681 0.14 0.2416 0.9866 1580665 IFLab1_003930 COc1ccccc1N=c2[nH]c(C)cs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C15 compound treatment 0.338 0.0131 0.51 0.334 0.00881 0.18 0.4936 0.9045 1219130 IFLab1_003931 CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C16 compound treatment 0.339 0.0141 0.55 0.342 0.0168 0.35 0.6397 0.9762 2067747 IFLab1_003932 COc1cccc(/N=C/2\NC(=O)\C(=C/3\C(=O)Nc4ccccc34)\S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C17 compound treatment 0.323 -0.00194 -0.08 0.337 0.0118 0.25 0.1209 0.4675 2067748 IFLab1_003933 CC(C)NC(=O)c1cc(Br)c(C)c(C)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C18 compound treatment 0.339 0.0141 0.55 0.342 0.0168 0.35 0.6397 0.9762 2067749 IFLab1_003934 Oc1ccccc1/C=N/c2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C19 compound treatment 0.335 0.0101 0.4 0.336 0.0108 0.23 0.4398 0.9649 1599486 IFLab1_003935 Cc1ccc(cc1NC(=O)c2cccc(Cl)c2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C20 compound treatment 0.341 0.0161 0.63 0.339 0.0138 0.29 0.651 0.9372 2067750 IFLab1_003936 O=C(N/C(=C\c1ccc(o1)c2ccccc2)/C(=O)N3CCOCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C21 compound treatment 0.337 0.0121 0.47 0.333 0.00781 0.16 0.451 0.8989 2067751 IFLab1_003937 CC(c1ccccc1)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C22 compound treatment 0.339 0.0141 0.55 0.331 0.00581 0.12 0.477 0.8425 1700925 IFLab1_003938 O=C(CSc1nnnn1c2ccccc2)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C23 mock treatment 0.325 6.25E-5 0.0 0.321 -0.00419 -0.09 -0.0602 -0.687 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 C24 positive control 0.079 -0.246 -9.67 0.079 -0.246 -5.15 -10.4804 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D01 compound treatment 0.346 0.0211 0.83 0.344 0.0188 0.39 0.864 0.9422 2067752 IFLab1_003939 Cc1sc2ncnc(SC3CCCCN(C(=O)c4ccccc4)C3=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D02 compound treatment 0.328 0.00306 0.12 0.323 -0.00219 -0.05 0.0528 0.4097 2067753 IFLab1_003940 CCOC(=O)CSc1nnc(CSc2nc3ccccc3s2)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D03 compound treatment 0.336 0.0111 0.43 0.335 0.00981 0.21 0.4528 0.9413 1652678 IFLab1_003941 Cc1sc2ncnc(n3nnc4ccccc34)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D04 compound treatment 0.33 0.00506 0.2 0.335 0.00981 0.21 0.2859 0.9999 1306053 IFLab1_003942 CSc1nc2ccc(NC(=O)c3coc4ccccc4c3=O)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D05 compound treatment 0.337 0.0121 0.47 0.327 0.00181 0.04 0.3622 0.7612 2067754 IFLab1_003943 CCN1CCN(CC1)S(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D06 compound treatment 0.34 0.0151 0.59 0.338 0.0128 0.27 0.6084 0.9358 2067755 IFLab1_003944 O=C(OCc1nc2ccccc2s1)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D07 compound treatment 0.338 0.0131 0.51 0.348 0.0228 0.48 0.7007 0.9993 1271140 IFLab1_003945 Cc1cc(NC(=O)c2cc(=O)c3ccccc3o2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D08 compound treatment 0.339 0.0141 0.55 0.339 0.0138 0.29 0.5954 0.9542 1192376 IFLab1_003946 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCC(C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D09 compound treatment 0.351 0.0261 1.02 0.35 0.0248 0.52 1.0917 0.9504 1722692 IFLab1_003947 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D10 compound treatment 0.361 0.0361 1.42 0.348 0.0228 0.48 1.3402 0.8958 2067756 IFLab1_003948 FC(F)(F)c1ccccc1NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D11 compound treatment 0.321 -0.00394 -0.15 0.325 -1.88E-4 0.0 -0.1122 -0.7248 2067757 IFLab1_003949 FC(F)(F)c1ccc(nc1)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D12 compound treatment 0.338 0.0131 0.51 0.344 0.0188 0.39 0.6415 0.9914 2067758 IFLab1_003950 Cc1ccccc1NC(=O)CSc2[nH]c(=O)cc(C)c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D13 compound treatment 0.34 0.0151 0.59 0.338 0.0128 0.27 0.6084 0.9358 1190709 IFLab1_003951 CCN(CC)Cc1oc(CO)cc(=O)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D14 compound treatment 0.34 0.0151 0.59 0.333 0.00781 0.16 0.5344 0.8698 1130052 IFLab1_003952 NC1=C(C#N)C(Cc2ccccc2)C3=C(CCCC3=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D15 compound treatment 0.281 -0.0439 -1.73 0.276 -0.0492 -1.03 -1.9494 -0.9694 1636340 IFLab1_003953 Oc1c(ccc2cccnc12)C(N3CCOCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D16 compound treatment 0.336 0.0111 0.43 0.33 0.00481 0.1 0.3788 0.8484 2067759 IFLab1_003954 COC(=O)CSC1=C(C#N)C2(CCCCC2)C(C(=N)N1)c3nc(cs3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D17 compound treatment 0.334 0.00906 0.36 0.335 0.00981 0.21 0.3972 0.9657 1688285 IFLab1_003955 CCOC(=O)N1CCN(CC(O)COCc2ccccc2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D18 compound treatment 0.338 0.0131 0.51 0.339 0.0138 0.29 0.5675 0.963 1205429 IFLab1_003956 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3ccccc3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D19 compound treatment 0.326 0.00106 0.04 0.328 0.00281 0.06 0.0712 0.9859 1250232 IFLab1_003957 CCOC(=O)N1CCN(CC(O)COc2cc(C)c(Cl)c(C)c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D20 compound treatment 0.337 0.0121 0.47 0.339 0.0138 0.29 0.5397 0.9718 1228488 IFLab1_003958 O=S(=O)(N=C1SCCS1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D21 compound treatment 0.34 0.0151 0.59 0.333 0.00781 0.16 0.5344 0.8698 2067760 IFLab1_003959 Nc1nc(SCC(=O)NCCO)nc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D22 compound treatment 0.34 0.0151 0.59 0.34 0.0148 0.31 0.6379 0.9544 1500854 IFLab1_003960 N#CC(N1CCCCCC1)c2c[nH]c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D23 mock treatment 0.325 6.25E-5 0.0 0.321 -0.00419 -0.09 -0.0602 -0.687 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 D24 positive control 0.08 -0.245 -9.63 0.081 -0.244 -5.11 -10.423 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E01 compound treatment 0.335 0.0101 0.4 0.327 0.00181 0.04 0.3066 0.7714 1506747 IFLab1_003961 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E02 compound treatment 0.323 -0.00194 -0.08 0.314 -0.0112 -0.23 -0.2194 -0.8912 1025087 IFLab1_003962 OC(=O)CCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E03 compound treatment 0.349 0.0241 0.95 0.342 0.0168 0.35 0.9178 0.9092 2067761 IFLab1_003963 CCOC(=O)c1oc2ccccc2c1NC(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E04 compound treatment 0.314 -0.0109 -0.43 0.324 -0.00119 -0.02 -0.3217 -0.7467 2067762 IFLab1_003964 CC(=C)Cn1c(CCCO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E05 compound treatment 0.329 0.00406 0.16 0.331 0.00581 0.12 0.199 0.991 1710571 IFLab1_003965 CC12COC3(CC2CCC13C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E06 compound treatment 0.33 0.00506 0.2 0.338 0.0128 0.27 0.3303 0.9892 2067763 IFLab1_003966 CCn1c(nc2ccccc12)c3cccc(Br)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E07 compound treatment 0.34 0.0151 0.59 0.346 0.0208 0.44 0.7267 0.9886 2067764 IFLab1_003967 CCN(CC)C(=O)C1(CCC2(C)C(=O)C1)C2(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E08 compound treatment 0.353 0.0281 1.1 0.343 0.0178 0.37 1.0438 0.8962 1178687 IFLab1_003968 Cc1cccc(NC(=O)Cn2nnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E09 compound treatment 0.341 0.0161 0.63 0.343 0.0178 0.37 0.7101 0.9684 1103732 IFLab1_003969 CC1(C)C2CCC(C2)(C(=O)O)C1=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E10 compound treatment 0.344 0.0191 0.75 0.344 0.0188 0.39 0.8083 0.9548 2067765 IFLab1_003970 OC(=O)/C=C\C(=O)Nc1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E11 compound treatment 0.338 0.0131 0.51 0.339 0.0138 0.29 0.5675 0.963 1470009 IFLab1_003971 Oc1ccc(O)c(Cc2nc3ccccc3s2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E12 compound treatment 0.338 0.0131 0.51 0.342 0.0168 0.35 0.6119 0.983 2067766 IFLab1_003972 CC(=O)/N=C/1\NC(=O)C(CC(=O)O)S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E13 compound treatment 0.337 0.0121 0.47 0.347 0.0218 0.46 0.6581 0.9998 2067767 IFLab1_003973 Cn1c(nc2ccccc12)/C(=N/O)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E14 compound treatment 0.345 0.0201 0.79 0.346 0.0208 0.44 0.8657 0.9608 2067768 IFLab1_003974 CC(C)C(=O)N=c1scc(c2ccc(C)cc2)n1c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E15 compound treatment 0.347 0.0221 0.87 0.351 0.0258 0.54 0.9953 0.974 1643271 IFLab1_003975 COc1ccc2cc(Br)ccc2c1CC(=O)NC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E16 compound treatment 0.353 0.0281 1.1 0.342 0.0168 0.35 1.029 0.8885 2067769 IFLab1_003976 OCc1csc2nc(=O)c3c4CCCCc4sc3n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E17 compound treatment 0.329 0.00406 0.16 0.335 0.00981 0.21 0.2581 0.9923 2067770 IFLab1_003977 CNC(=O)c1cc(Br)c(C)c(C)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E18 compound treatment 0.338 0.0131 0.51 0.33 0.00481 0.1 0.4344 0.83 1057181 IFLab1_003978 C(Cc1ccccn1)N2CCN(CCc3ccccn3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E19 compound treatment 0.341 0.0161 0.63 0.337 0.0118 0.25 0.6214 0.9162 1409934 IFLab1_003979 Cc1ccc2cccc(OC(=O)N3CCOCC3)c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E20 compound treatment 0.342 0.0171 0.67 0.339 0.0138 0.29 0.6788 0.9292 2067771 IFLab1_003980 Cc1ccc(cc1)C(=O)CC(c2ccccc2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E21 compound treatment 0.337 0.0121 0.47 0.336 0.0108 0.23 0.4954 0.9427 2067772 IFLab1_003981 Cc1nc2ccccc2n1C(=O)/C=C\C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E22 compound treatment 0.331 0.00606 0.24 0.333 0.00781 0.16 0.2842 0.9831 1518257 IFLab1_003982 CCN1CCN(CC1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E23 mock treatment 0.321 -0.00394 -0.15 0.319 -0.00619 -0.13 -0.201 -0.9961 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 E24 positive control 0.081 -0.244 -9.59 0.081 -0.244 -5.11 -10.3952 -0.9565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F01 compound treatment 0.341 0.0161 0.63 0.333 0.00781 0.16 0.5622 0.8617 1681080 IFLab1_003983 COc1ccc(CCNc2ncnc3sc(C)c(C)c23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F02 compound treatment 0.32 -0.00494 -0.19 0.321 -0.00419 -0.09 -0.1992 -0.9354 1118702 IFLab1_003984 O=C(c1ccccc1)c2ccccc2NS(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F03 compound treatment 0.321 -0.00394 -0.15 0.317 -0.00819 -0.17 -0.2306 -0.9987 1181804 IFLab1_003985 COC(=O)c1ccc(Oc2ncnc3sc4CCCCc4c23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F04 compound treatment 0.331 0.00606 0.24 0.321 -0.00419 -0.09 0.1066 0.4197 1164174 IFLab1_003986 Cc1nc2cc(NC(=O)c3ccc4OCCOc4c3)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F05 compound treatment 0.321 -0.00394 -0.15 0.323 -0.00219 -0.05 -0.1418 -0.8786 1603298 IFLab1_003987 C1CCCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F06 compound treatment 0.375 0.0501 1.97 0.369 0.0438 0.92 2.0401 0.9395 1691025 IFLab1_003988 CCOC(=O)c1sc(NC(=O)Cc2cccc3ccccc23)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F07 compound treatment 0.332 0.00706 0.28 0.321 -0.00419 -0.09 0.1344 0.4615 1347874 IFLab1_003989 O=C(N1CCN(CC1)c2ccccc2)c3cc(=O)c4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F08 compound treatment 0.339 0.0141 0.55 0.334 0.00881 0.18 0.5214 0.8945 1596702 IFLab1_003990 Fc1ccc(cc1)S(=O)(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F09 compound treatment 0.347 0.0221 0.87 0.318 -0.00719 -0.15 0.507 0.5759 2067773 IFLab1_003991 CC(C)(CSc1ccccn1)NS(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F10 compound treatment 0.349 0.0241 0.95 0.368 0.0428 0.9 1.3025 0.9996 2067774 IFLab1_003992 COC(=O)c1ccc(/C=C\2/SC(=S)N(CCC(=O)N(Cc3ccccc3)C(C)(C)C)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F11 compound treatment 0.345 0.0201 0.79 0.331 0.00581 0.12 0.6438 0.8066 2067775 IFLab1_003993 CCOC(=O)N1CCN(CC1)c2ccc(cn2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F12 compound treatment 0.345 0.0201 0.79 0.357 0.0318 0.67 1.0285 0.9964 2067776 IFLab1_003994 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC#N)c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F13 compound treatment 0.346 0.0211 0.83 0.343 0.0178 0.37 0.8492 0.935 1447178 IFLab1_003995 CCOC(=O)N1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F14 compound treatment 0.349 0.0241 0.95 0.339 0.0138 0.29 0.8734 0.8829 2067777 IFLab1_003996 CCCC(C)C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F15 compound treatment 0.21 -0.115 -4.52 0.213 -0.112 -2.35 -4.8555 -0.9535 1371058 IFLab1_003997 CCN(CC)Cc1cc(Cl)c2cccnc2c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F16 compound treatment 0.343 0.0181 0.71 0.346 0.0208 0.44 0.8101 0.9724 2067778 IFLab1_003998 CSC1=C(C#N)C2(CCCCC2)C(C(=N)N1)c3nc(cs3)c4ccc(C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F17 compound treatment 0.336 0.0111 0.43 0.336 0.0108 0.23 0.4676 0.9536 1443895 IFLab1_003999 CCOC(=O)N1CCN(CC(O)COC2CC(C)CCC2C(C)C)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F18 compound treatment 0.324 -9.37E-4 -0.04 0.337 0.0118 0.25 0.1487 0.5951 1367941 IFLab1_004000 CC(NC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F19 compound treatment 0.328 0.00306 0.12 0.354 0.0288 0.6 0.5115 0.8319 1574885 IFLab1_004001 CCOC(=O)N1CCN(CC(O)COc2ccc3ccccc3c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F20 compound treatment 0.384 0.0591 2.32 0.387 0.0618 1.29 2.5567 0.9618 1576686 IFLab1_004002 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3)C(=O)CC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F21 compound treatment 0.341 0.0161 0.63 0.337 0.0118 0.25 0.6214 0.9162 1358709 IFLab1_004003 Nc1nc(SCc2ccc(cc2)C(=O)NCCO)nc3sc4CCCCc4c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F22 compound treatment 0.347 0.0221 0.87 0.348 0.0228 0.48 0.9509 0.9604 1290396 IFLab1_004004 Clc1cccc(c1)C(=O)Oc2ccc3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F23 mock treatment 0.322 -0.00294 -0.12 0.329 0.00381 0.08 -0.0253 -0.1799 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 F24 positive control 0.081 -0.244 -9.59 0.082 -0.243 -5.09 -10.3804 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G01 compound treatment 0.339 0.0141 0.55 0.33 0.00481 0.1 0.4622 0.8224 2067779 IFLab1_004005 O=C(CSc1nc2ccccc2s1)NCCCN3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G02 compound treatment 0.311 -0.0139 -0.55 0.307 -0.0182 -0.38 -0.6566 -0.9841 1042426 IFLab1_004006 OC(C(O)c1nc2ccccc2[nH]1)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G03 compound treatment 0.32 -0.00494 -0.19 0.315 -0.0102 -0.21 -0.288 -0.9989 1232473 IFLab1_004007 O=C(Nc1ccccc1c2nc3ccccc3o2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G04 compound treatment 0.332 0.00706 0.28 0.331 0.00581 0.12 0.2824 0.9314 1605646 IFLab1_004008 CC(c1ccccc1)n2c(CCCO)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G05 compound treatment 0.329 0.00406 0.16 0.316 -0.00919 -0.19 -0.023 -0.092 1140709 IFLab1_004009 CC1(C)C2(C)CCC1(OC2=O)C(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G06 compound treatment 0.32 -0.00494 -0.19 0.312 -0.0132 -0.28 -0.3324 -0.9852 2067780 IFLab1_004010 C=CCn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G07 compound treatment 0.324 -9.37E-4 -0.04 0.337 0.0118 0.25 0.1487 0.5951 1314249 IFLab1_004011 CC1(C)C2(C)CCC1(CC2=O)C(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G08 compound treatment 0.347 0.0221 0.87 0.341 0.0158 0.33 0.8474 0.9127 1499128 IFLab1_004012 Cc1ccc(NC(=O)Cn2nnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G09 compound treatment 0.339 0.0141 0.55 0.327 0.00181 0.04 0.4178 0.7538 2067781 IFLab1_004013 CC1(C)C2CCC(C2)(C(=O)N)C1=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G10 compound treatment 0.091 -0.234 -9.2 0.088 -0.237 -4.96 -10.0136 -0.9581 2067782 IFLab1_004014 COC(=O)/C=C\C(=O)Nc1ccc(NC(=O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G11 compound treatment 0.31 -0.0149 -0.59 0.317 -0.00819 -0.17 -0.5364 -0.8768 1218937 IFLab1_004015 Oc1ccc(O)c(Cc2nc3ccccc3[nH]2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G12 compound treatment 0.339 0.0141 0.55 0.339 0.0138 0.29 0.5954 0.9542 1874778 IFLab1_004016 OC(=O)CCC(=O)N=c1[nH]c(cs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G13 compound treatment 0.33 0.00506 0.2 0.34 0.0148 0.31 0.3599 0.9771 1532898 IFLab1_004017 COC(Cc1nc2ccccc2s1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G14 compound treatment 0.315 -0.00994 -0.39 0.3 -0.0252 -0.53 -0.649 -0.9891 2067783 IFLab1_004018 COC(=O)c1sc(=Nc2ccccc2)n(c1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G15 compound treatment 0.32 -0.00494 -0.19 0.332 0.00681 0.14 -0.0365 -0.1514 2067784 IFLab1_004019 O[C@@H]1CCCC[C@@H]1c2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G16 compound treatment 0.323 -0.00194 -0.08 0.325 -1.88E-4 0.0 -0.0566 -0.7425 1661218 IFLab1_004020 OCCNC(=O)c1ccc(CSc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G17 compound treatment 0.338 0.0131 0.51 0.339 0.0138 0.29 0.5675 0.963 1276443 IFLab1_004021 Cc1ccc2cccc(OCc3ccccc3)c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G18 compound treatment 0.322 -0.00294 -0.12 0.334 0.00881 0.18 0.0487 0.224 1580956 IFLab1_004022 Nc1ncc(Cc2ccc(Cl)cc2Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G19 compound treatment 0.337 0.0121 0.47 0.332 0.00681 0.14 0.4362 0.8807 1499659 IFLab1_004023 COc1ccc(CN2CCN(Cc3c[nH]c4ccccc34)CC2)c(OC)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G20 compound treatment 0.333 0.00806 0.32 0.337 0.0118 0.25 0.3989 0.9924 2067785 IFLab1_004024 CC(=O)Nc1nc(Br)sc1Cc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G21 compound treatment 0.33 0.00506 0.2 0.335 0.00981 0.21 0.2859 0.9999 2067786 IFLab1_004025 Cn1c(Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G22 compound treatment 0.337 0.0121 0.47 0.329 0.00381 0.08 0.3918 0.8146 1271881 IFLab1_004026 COc1ccc2c(C)cc(nc2c1)N3CC(C)OC(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G23 mock treatment 0.32 -0.00494 -0.19 0.316 -0.00919 -0.19 -0.2732 -1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 G24 positive control 0.081 -0.244 -9.59 0.082 -0.243 -5.09 -10.3804 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H01 compound treatment 0.347 0.0221 0.87 0.337 0.0118 0.25 0.7882 0.8738 1218095 IFLab1_004027 C(Nc1nc(nc2ccccc12)c3ccccc3)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H02 compound treatment 0.32 -0.00494 -0.19 0.317 -0.00819 -0.17 -0.2584 -0.9981 2067787 IFLab1_004028 O=C(NC1CCS(=O)(=O)C1)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H03 compound treatment 0.359 0.0341 1.34 0.355 0.0298 0.62 1.3881 0.9396 1125766 IFLab1_004029 CCOC(=O)C1=C(C)NC2=C(C1c3ccc4OCCOc4c3)C(=O)CC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H04 compound treatment 0.33 0.00506 0.2 0.329 0.00381 0.08 0.1972 0.9194 1502661 IFLab1_004030 Cc1cccc(NC(=O)c2coc3ccccc3c2=O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H05 compound treatment 0.328 0.00306 0.12 0.329 0.00381 0.08 0.1416 0.98 1624933 IFLab1_004031 CC1CCN(CCC(=O)Nc2sc3CCCCc3c2C#N)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H06 compound treatment 0.347 0.0221 0.87 0.355 0.0298 0.62 1.0545 0.9869 1562302 IFLab1_004032 CCOC(=O)c1sc(NC(=O)CCOc2ccccc2)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H07 compound treatment 0.382 0.0571 2.24 0.369 0.0438 0.92 2.2348 0.922 1721633 IFLab1_004033 O=C(Nc1nccs1)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H08 compound treatment 0.337 0.0121 0.47 0.339 0.0138 0.29 0.5397 0.9718 2067788 IFLab1_004034 OC(=O)CSc1nnc(c2ccncc2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H09 compound treatment 0.338 0.0131 0.51 0.347 0.0218 0.46 0.6859 0.9983 1728558 IFLab1_004035 Cc1ccc(cc1)S(=O)(=O)NC(C)(C)CSc2ncccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H10 compound treatment 0.346 0.0211 0.83 0.333 0.00781 0.16 0.7012 0.8307 1030654 IFLab1_004036 ONC(=O)COc1ccc(Cl)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H11 compound treatment 0.341 0.0161 0.63 0.34 0.0148 0.31 0.6658 0.9463 1158237 IFLab1_004037 CCN1CCN(CC1)S(=O)(=O)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H12 compound treatment 0.336 0.0111 0.43 0.348 0.0228 0.48 0.6451 0.9989 2067789 IFLab1_004038 NC1=C(C#N)C(C2CCCCC2)C3=C(CC(CC3=O)c4ccccc4)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H13 compound treatment 0.342 0.0171 0.67 0.343 0.0178 0.37 0.7379 0.9615 1593651 IFLab1_004039 Clc1ccc(c2ncc3ccccn23)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H14 compound treatment 0.341 0.0161 0.63 0.327 0.00181 0.04 0.4734 0.7482 2067790 IFLab1_004040 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2CCc3ccccc3)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H15 compound treatment 0.341 0.0161 0.63 0.337 0.0118 0.25 0.6214 0.9162 1352508 IFLab1_004041 COc1ccc(OC)c(c1)C2SCCN2C(=O)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H16 compound treatment 0.346 0.0211 0.83 0.343 0.0178 0.37 0.8492 0.935 1502136 IFLab1_004042 Cc1cc(C)c(C(=O)N)c(SCC(=O)c2ccc(Cl)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H17 compound treatment 0.332 0.00706 0.28 0.339 0.0138 0.29 0.4007 0.9998 1287574 IFLab1_004043 CCOC(=O)N1CCN(CC(O)COC2C(C)(C)C3CCC2(C)C3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H18 compound treatment 0.343 0.0181 0.71 0.337 0.0118 0.25 0.677 0.9003 1195797 IFLab1_004044 NC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H19 compound treatment 0.336 0.0111 0.43 0.336 0.0108 0.23 0.4676 0.9536 1130221 IFLab1_004045 OC(COc1ccccc1CC=C)CN2CCN(Cc3ccc4OCOc4c3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H20 compound treatment 0.327 0.00206 0.08 0.332 0.00681 0.14 0.1581 0.9642 2067791 IFLab1_004046 Clc1cccc(c1)C(=O)Sc2nc3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H21 compound treatment 0.322 -0.00294 -0.12 0.324 -0.00119 -0.02 -0.0992 -0.84 1270665 IFLab1_004047 Nc1nc(SCC(=O)N2CCCCC2)nc3sc4CCCCc4c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H22 compound treatment 0.347 0.0221 0.87 0.341 0.0158 0.33 0.8474 0.9127 1305578 IFLab1_004048 COc1cccc(c1)C(=O)Oc2ccc3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H23 mock treatment 0.326 0.00106 0.04 0.32 -0.00519 -0.11 -0.0472 -0.406 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 H24 positive control 0.082 -0.243 -9.55 0.084 -0.241 -5.05 -10.323 -0.9555 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I01 compound treatment 0.328 0.00306 0.12 0.347 0.0218 0.46 0.4079 0.8641 2067792 IFLab1_004049 COC(=O)c1ccc(CSc2nc(C)cc(C)n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I02 compound treatment 0.332 0.00706 0.28 0.332 0.00681 0.14 0.2972 0.952 1111780 IFLab1_004050 COc1ccc(cc1OC)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I03 compound treatment 0.343 0.0181 0.71 0.338 0.0128 0.27 0.6918 0.9113 1198571 IFLab1_004051 O=C(Nc1ccccc1c2nc3ccccc3o2)C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I04 compound treatment 0.318 -0.00694 -0.27 0.327 0.00181 0.04 -0.1661 -0.603 1466951 IFLab1_004052 CC(c1ccccc1)n2c(CO)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I05 compound treatment 0.327 0.00206 0.08 0.334 0.00881 0.18 0.1877 0.9319 1187141 IFLab1_004053 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I06 compound treatment 0.337 0.0121 0.47 0.35 0.0248 0.52 0.7025 0.999 1527969 IFLab1_004054 Clc1ccc(nn1)n2ccnc2C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I07 compound treatment 0.349 0.0241 0.95 0.338 0.0128 0.27 0.8586 0.8731 1510527 IFLab1_004055 CC1(C)C2(C)CCC1(CC2=O)C(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I08 compound treatment 0.346 0.0211 0.83 0.337 0.0118 0.25 0.7604 0.8798 1718880 IFLab1_004056 COCn1ccnc1P(=O)(O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I09 compound treatment 0.337 0.0121 0.47 0.351 0.0258 0.54 0.7173 0.9979 1578960 IFLab1_004057 CC1(C)C2(C)CCC1(CC2O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I10 compound treatment 0.344 0.0191 0.75 0.329 0.00381 0.08 0.5864 0.778 1241726 IFLab1_004058 NC(=O)CSc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I11 compound treatment 0.437 0.112 4.41 0.434 0.109 2.28 4.7257 0.9528 2067793 IFLab1_004059 CC(O)CCc1sc2ccccc2[n+]1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I12 compound treatment 0.343 0.0181 0.71 0.364 0.0388 0.81 1.0765 0.9978 1210609 IFLab1_004060 CCOC(=O)Cc1csc(Nc2ccc(Cl)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I13 compound treatment 0.35 0.0251 0.99 0.352 0.0268 0.56 1.0935 0.9644 1149957 IFLab1_004061 CC(=O)SC(CC(=O)O)c1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I14 compound treatment 0.341 0.0161 0.63 0.335 0.00981 0.21 0.5918 0.8911 1983767 IFLab1_004062 COC(=O)c1sc(=Nc2ccccc2)[nH]c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I15 compound treatment 0.338 0.0131 0.51 0.334 0.00881 0.18 0.4936 0.9045 2067794 IFLab1_004063 NC(=O)Cc1nc(cs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I16 compound treatment 0.333 0.00806 0.32 0.334 0.00881 0.18 0.3546 0.9668 1011848 IFLab1_004064 CN(C)CCC(O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I17 compound treatment 0.341 0.0161 0.63 0.356 0.0308 0.64 0.9025 0.9999 1922612 IFLab1_004065 Cc1nc(co1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I18 compound treatment 0.341 0.0161 0.63 0.348 0.0228 0.48 0.7841 0.9905 1620515 IFLab1_004066 COc1ccc(Cc2cnc(N)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I19 compound treatment 0.346 0.0211 0.83 0.317 -0.00819 -0.17 0.4644 0.5492 1665570 IFLab1_004067 COc1cc(OC)c(OC)cc1CN2CCN(Cc3ccc(F)cc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I20 compound treatment 0.335 0.0101 0.4 0.34 0.0148 0.31 0.4989 0.9927 2067795 IFLab1_004068 COc1ccc(cc1)S(=O)(=O)CC(SC#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I21 compound treatment 0.325 6.25E-5 0.0 0.345 0.0198 0.41 0.2949 0.7113 2067796 IFLab1_004069 CC(C)n1c(nc2ccccc12)C(C)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I22 compound treatment 0.341 0.0161 0.63 0.333 0.00781 0.16 0.5622 0.8617 1153758 IFLab1_004070 C(Nc1ncnc2sc3CCCCc3c12)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I23 mock treatment 0.327 0.00206 0.08 0.329 0.00381 0.08 0.1138 1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 I24 positive control 0.083 -0.242 -9.51 0.085 -0.24 -5.03 -10.2804 -0.9555 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J01 compound treatment 0.356 0.0311 1.22 0.353 0.0278 0.58 1.2751 0.9425 2067797 IFLab1_004071 COC(=O)c1cccc(c1)N2C(=O)/C(=C\c3cccnc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J02 compound treatment 0.343 0.0181 0.71 0.354 0.0288 0.6 0.9285 0.9967 2067798 IFLab1_004072 FC(F)(F)c1cccc(NC(=O)CCCN2C(=O)/C(=C/c3cccs3)/SC2=S)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J03 compound treatment 0.29 -0.0349 -1.37 0.287 -0.0382 -0.8 -1.5364 -0.9668 2067799 IFLab1_004073 Cc1sc2ncnc(SCc3ccccc3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J04 compound treatment 0.328 0.00306 0.12 0.322 -0.00319 -0.07 0.038 0.2759 1280766 IFLab1_004074 O=C(N1CCN(CC1)c2ccccc2)c3coc4ccccc4c3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J05 compound treatment 0.346 0.0211 0.83 0.339 0.0138 0.29 0.79 0.9006 2067800 IFLab1_004075 O=C(CSc1ncnc2sc3CCCc3c12)NCCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J06 compound treatment 0.34 0.0151 0.59 0.333 0.00781 0.16 0.5344 0.8698 1251832 IFLab1_004076 CCC(=O)Nc1ccccc1c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J07 compound treatment 0.444 0.119 4.68 0.417 0.0918 1.92 4.6687 0.9226 1556547 IFLab1_004077 CC1(C)CC(=O)c2sc(NC(=O)c3cc(=O)c4ccccc4o3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J08 compound treatment 0.35 0.0251 0.99 0.342 0.0168 0.35 0.9456 0.9037 1340014 IFLab1_004078 O=C(COC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3ccccc3c2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J09 compound treatment 0.332 0.00706 0.28 0.337 0.0118 0.25 0.3711 0.9983 1983663 IFLab1_004079 Cc1ccc(cc1)S(=O)(=O)NCCSc2ncccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J10 compound treatment 0.338 0.0131 0.51 0.337 0.0118 0.25 0.538 0.9438 2067801 IFLab1_004080 ONC(=O)CCCOc1ccc(Cl)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J11 compound treatment 0.328 0.00306 0.12 0.344 0.0188 0.39 0.3635 0.883 1662497 IFLab1_004081 Fc1ccc(cc1)S(=O)(=O)N2CCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J12 compound treatment 0.357 0.0321 1.26 0.363 0.0378 0.79 1.4509 0.9748 1247646 IFLab1_004082 CCOC(=O)C1=C(OC(=C(C#N)C1C(C)C)N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J13 compound treatment 0.344 0.0191 0.75 0.327 0.00181 0.04 0.5568 0.7419 1193394 IFLab1_004083 Clc1ccccc1c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J14 compound treatment 0.34 0.0151 0.59 0.343 0.0178 0.37 0.6823 0.9751 2067802 IFLab1_004084 CCOC(=O)/C(=C(\C)/O)/C1(CCCCC1)C(C#N)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J15 compound treatment 0.34 0.0151 0.59 0.338 0.0128 0.27 0.6084 0.9358 1285402 IFLab1_004085 Fc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J16 compound treatment 0.333 0.00806 0.32 0.338 0.0128 0.27 0.4137 0.9965 1535652 IFLab1_004086 CCCSc1nc(C)cc(C)c1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J17 compound treatment 0.325 6.25E-5 0.0 0.329 0.00381 0.08 0.0582 0.7285 1180294 IFLab1_004087 CCOC(=O)N1CCN(CC(O)COc2cc(C)ccc2C(C)C)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J18 compound treatment 0.339 0.0141 0.55 0.342 0.0168 0.35 0.6397 0.9762 1280339 IFLab1_004088 Cc1cc(C)c(NC(=O)Cn2cnc3ccccc23)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J19 compound treatment 0.332 0.00706 0.28 0.331 0.00581 0.12 0.2824 0.9314 1370921 IFLab1_004089 Cc1cc(OCC(O)CN2CCN(Cc3ccc4OCOc4c3)CC2)cc(C)c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J20 compound treatment 0.335 0.0101 0.4 0.344 0.0188 0.39 0.5581 1.0 1913413 IFLab1_004090 OC(=O)CSc1nnnn1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J21 compound treatment 0.355 0.0301 1.18 0.349 0.0238 0.5 1.1882 0.9263 2067803 IFLab1_004091 Cc1sc2nc(SCC=C)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J22 compound treatment 0.329 0.00406 0.16 0.346 0.0208 0.44 0.4209 0.9073 1458176 IFLab1_004092 COc1ccc(cc1OC)C(C#N)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J23 mock treatment 0.323 -0.00194 -0.08 0.323 -0.00219 -0.05 -0.0862 -0.9703 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 J24 positive control 0.084 -0.241 -9.47 0.086 -0.239 -5.01 -10.2378 -0.9555 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K01 compound treatment 0.333 0.00806 0.32 0.334 0.00881 0.18 0.3546 0.9668 2067804 IFLab1_004093 ICC1COC[N+]21CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K02 compound treatment 0.328 0.00306 0.12 0.328 0.00281 0.06 0.1268 0.9458 1721556 IFLab1_004094 O=C(CSc1nc2ccccc2[nH]1)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K03 compound treatment 0.323 -0.00194 -0.08 0.315 -0.0102 -0.21 -0.2046 -0.9038 1244153 IFLab1_004095 O=C(COc1ccccc1)Nc2ccccc2c3nc4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K04 compound treatment 0.321 -0.00394 -0.15 0.316 -0.00919 -0.19 -0.2454 -0.9942 2067805 IFLab1_004096 CC(O)c1nc2ccccc2n1CC(=C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K05 compound treatment 0.318 -0.00694 -0.27 0.321 -0.00419 -0.09 -0.2548 -0.8895 1490821 IFLab1_004097 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCc4ccccc4C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K06 compound treatment 0.326 0.00106 0.04 0.325 -1.88E-4 0.0 0.0268 0.6379 1120666 IFLab1_004098 OP(=O)(c1nccn1c2ccc(NC(=O)c3ccccc3Cl)cc2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K07 compound treatment 0.329 0.00406 0.16 0.324 -0.00119 -0.02 0.0954 0.59 1262122 IFLab1_004099 CC1(C)C2(C)CCC1(CC2=O)C(=O)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K08 compound treatment 0.349 0.0241 0.95 0.335 0.00981 0.21 0.8142 0.841 1717379 IFLab1_004100 O=P(N1CCCCCC1)(c2nc3ccccc3s2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K09 compound treatment 0.339 0.0141 0.55 0.329 0.00381 0.08 0.4474 0.8008 2067806 IFLab1_004101 CC12C=C(Br)C2CCC1(C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K10 compound treatment 0.35 0.0251 0.99 0.333 0.00781 0.16 0.8124 0.8133 2067807 IFLab1_004102 CCS/C(=N/c1ccccc1)/Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K11 compound treatment 0.343 0.0181 0.71 0.333 0.00781 0.16 0.6178 0.8477 2067808 IFLab1_004103 C[n+]1ccsc1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K12 compound treatment 0.343 0.0181 0.71 0.34 0.0148 0.31 0.7214 0.9309 1689552 IFLab1_004104 OC(=O)CCC(=O)Nc1nc(cs1)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K13 compound treatment 0.344 0.0191 0.75 0.328 0.00281 0.06 0.5716 0.7603 1613969 IFLab1_004105 Cc1ccc(cc1)C(O)C(C)(C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K14 compound treatment 0.344 0.0191 0.75 0.334 0.00881 0.18 0.6604 0.8556 1362321 IFLab1_004106 COC(=O)c1sc(N)nc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K15 compound treatment 0.344 0.0191 0.75 0.337 0.0118 0.25 0.7048 0.893 1263917 IFLab1_004107 OC(=O)CCc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K16 compound treatment 0.331 0.00606 0.24 0.33 0.00481 0.1 0.2398 0.9266 2067809 IFLab1_004108 COC(=O)c1ccc(CSc2nccc(O)n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K17 compound treatment 0.339 0.0141 0.55 0.339 0.0138 0.29 0.5954 0.9542 1330843 IFLab1_004109 Clc1ccc(NC(=O)c2cc3ccccc3oc2=N)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K18 compound treatment 0.393 0.0681 2.68 0.378 0.0528 1.11 2.6737 0.9235 2067810 IFLab1_004110 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C(\C#N)/c3ccc(Cl)cc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K19 compound treatment 0.352 0.0271 1.06 0.326 8.12E-4 0.02 0.7644 0.7183 1609689 IFLab1_004111 CC(C)Cc1cc2c3ccccc3oc(=O)c2c(N)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K20 compound treatment 0.343 0.0181 0.71 0.334 0.00881 0.18 0.6326 0.8621 2067811 IFLab1_004112 Cc1ccc(cc1)S(=O)(=O)CC(SC#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K21 compound treatment 0.339 0.0141 0.55 0.337 0.0118 0.25 0.5658 0.9341 1038915 IFLab1_004113 OCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K22 compound treatment 0.341 0.0161 0.63 0.337 0.0118 0.25 0.6214 0.9162 2067812 IFLab1_004114 Cc1sc2ncnc(Sc3nnc4ccccn34)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K23 mock treatment 0.322 -0.00294 -0.12 0.322 -0.00319 -0.07 -0.1288 -0.966 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 K24 positive control 0.086 -0.239 -9.39 0.087 -0.238 -4.98 -10.1674 -0.956 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L01 compound treatment 0.429 0.104 4.09 0.423 0.0978 2.05 4.3405 0.9488 2067813 IFLab1_004115 OC(=O)c1c(NC(=O)/C=C/c2ccco2)sc3CCCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L02 compound treatment 0.315 -0.00994 -0.39 0.312 -0.0132 -0.28 -0.4714 -0.9855 2067814 IFLab1_004116 CCc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCCc4ccccc34)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L03 compound treatment 0.33 0.00506 0.2 0.32 -0.00519 -0.11 0.064 0.2822 2067815 IFLab1_004117 O=C(CSc1nnc2sc3ccccc3n12)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L04 compound treatment 0.317 -0.00794 -0.31 0.317 -0.00819 -0.17 -0.3418 -0.9601 1721996 IFLab1_004118 Cc1cc(NC(=O)c2coc3ccccc3c2=O)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L05 compound treatment 0.317 -0.00794 -0.31 0.321 -0.00419 -0.09 -0.2826 -0.8719 2067816 IFLab1_004119 Fc1ccc(cc1)C(=O)CSc2ncnc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L06 compound treatment 0.321 -0.00394 -0.15 0.324 -0.00119 -0.02 -0.127 -0.8102 1437264 IFLab1_004120 COC(=O)c1c(NC(=O)c2ccc(Cl)s2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L07 compound treatment 0.33 0.00506 0.2 0.319 -0.00619 -0.13 0.0492 0.2072 1590309 IFLab1_004121 O=C(N1CCN(CC1)c2ccccc2)c3ccc(C#N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L08 compound treatment 0.33 0.00506 0.2 0.318 -0.00719 -0.15 0.0344 0.1379 1865398 IFLab1_004122 OC(=O)C1CCN(CC1)S(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L09 compound treatment 0.33 0.00506 0.2 0.323 -0.00219 -0.05 0.1084 0.5306 2067817 IFLab1_004123 Cc1ccc(cc1)S(=O)(=O)NCCSc2nncn2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L10 compound treatment 0.322 -0.00294 -0.12 0.325 -1.88E-4 0.0 -0.0844 -0.7307 1004471 IFLab1_004124 NC(=O)COc1ccc(Cl)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L11 compound treatment 0.333 0.00806 0.32 0.325 -1.88E-4 0.0 0.2214 0.6983 1310812 IFLab1_004125 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L12 compound treatment 0.34 0.0151 0.59 0.338 0.0128 0.27 0.6084 0.9358 1199043 IFLab1_004126 CCCc1n[nH]c2OC(=C(C#N)C(C(C)C)c12)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L13 compound treatment 0.333 0.00806 0.32 0.328 0.00281 0.06 0.2658 0.8243 2067818 IFLab1_004127 Fc1ccccc1c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L14 compound treatment 0.337 0.0121 0.47 0.336 0.0108 0.23 0.4954 0.9427 2067819 IFLab1_004128 C/C(=C(\C(=O)Nc1ccccc1)/C2(CCCC2)C(C#N)C(=O)N)/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L15 compound treatment 0.339 0.0141 0.55 0.328 0.00281 0.06 0.4326 0.778 1706740 IFLab1_004129 CC1CC(CC(C)(C)C1)OCC(O)CN2CCN(CC2)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L16 compound treatment 0.342 0.0171 0.67 0.336 0.0108 0.23 0.6344 0.896 1547286 IFLab1_004130 Cc1cc(C)c(C(=O)N)c(SCC(=O)Nc2nccs2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L17 compound treatment 0.333 0.00806 0.32 0.332 0.00681 0.14 0.325 0.9349 2067820 IFLab1_004131 CCOC(=O)N1CCN(CC(O)COCCC2(CC3CC4CC(C3)C2)C4)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L18 compound treatment 0.334 0.00906 0.36 0.339 0.0138 0.29 0.4563 0.9946 1687920 IFLab1_004132 C(Cn1cnc2ccccc12)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L19 compound treatment 0.329 0.00406 0.16 0.33 0.00481 0.1 0.1842 0.9753 1147315 IFLab1_004133 CC(C)(C)c1ccccc1OCC(O)CN2CCN(Cc3ccc4OCOc4c3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L20 compound treatment 0.337 0.0121 0.47 0.339 0.0138 0.29 0.5397 0.9718 1160809 IFLab1_004134 COc1ccc(cc1)C(=O)Sc2nnnn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L21 compound treatment 0.35 0.0251 0.99 0.351 0.0258 0.54 1.0787 0.96 2067821 IFLab1_004135 CCOC(=O)CSc1nc(N)c2c(C)c(C)sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L22 compound treatment 0.339 0.0141 0.55 0.326 8.12E-4 0.02 0.403 0.7285 1409803 IFLab1_004136 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3ccc(OC)cc3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L23 mock treatment 0.327 0.00206 0.08 0.326 8.12E-4 0.02 0.0694 0.8372 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 L24 positive control 0.085 -0.24 -9.43 0.088 -0.237 -4.96 -10.1804 -0.955 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M01 compound treatment 0.332 0.00706 0.28 0.324 -0.00119 -0.02 0.1788 0.6413 1262449 IFLab1_004137 CC(=O)Nc1ccccc1c2nc3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M02 compound treatment 0.315 -0.00994 -0.39 0.313 -0.0122 -0.26 -0.4566 -0.9786 1522274 IFLab1_004138 Cc1nc2ccccc2n1C(=O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M03 compound treatment 0.335 0.0101 0.4 0.321 -0.00419 -0.09 0.2178 0.5375 2067822 IFLab1_004139 O=C(Nc1ccccc1c2nc3ccccc3o2)/C=C/c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M04 compound treatment 0.343 0.0181 0.71 0.337 0.0118 0.25 0.677 0.9003 1419243 IFLab1_004140 CC(O)c1nc2ccccc2n1Cc3cccc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M05 compound treatment 0.3 -0.0249 -0.98 0.324 -0.00119 -0.02 -0.7109 -0.7248 1412759 IFLab1_004141 CC1Cc2ccccc2N1C(=O)C3(CCC4(C)C(=O)O3)C4(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M06 compound treatment 0.324 -9.37E-4 -0.04 0.31 -0.0152 -0.32 -0.2508 -0.7839 1612011 IFLab1_004142 OP(=O)(c1nccn1c2ccc(Cl)nn2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M07 compound treatment 0.333 0.00806 0.32 0.334 0.00881 0.18 0.3546 0.9668 1562590 IFLab1_004143 CC1Cc2ccccc2N1C(=O)C3(CCC4(C)C(=O)C3)C4(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M08 compound treatment 0.337 0.0121 0.47 0.325 -1.88E-4 0.0 0.3326 0.7012 1556156 IFLab1_004144 Cn1c(nc2ccccc12)P(=O)(O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M09 compound treatment 0.336 0.0111 0.43 0.331 0.00581 0.12 0.3936 0.8714 2067823 IFLab1_004145 CC1(CBr)C2CCC1(C)/C(=N\O)/C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M10 compound treatment 0.344 0.0191 0.75 0.347 0.0218 0.46 0.8527 0.9717 1737929 IFLab1_004146 OC1(CSC(=S)N1Cc2ccco2)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M11 compound treatment 0.345 0.0201 0.79 0.332 0.00681 0.14 0.6586 0.8216 1411978 IFLab1_004147 COC(CC(=O)O)c1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M12 compound treatment 0.352 0.0271 1.06 0.35 0.0248 0.52 1.1195 0.9456 1673424 IFLab1_004148 CCOc1ccc(cc1)n2c(csc2=NC(=O)C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M13 compound treatment 0.354 0.0291 1.14 0.36 0.0348 0.73 1.3231 0.9764 2067824 IFLab1_004149 COc1ccc2cc(Br)ccc2c1CC#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M14 compound treatment 0.363 0.0381 1.5 0.356 0.0308 0.64 1.5141 0.9292 1495820 IFLab1_004150 O=C(CSc1nc2ccccc2c(=O)[nH]1)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M15 compound treatment 0.302 -0.0229 -0.9 0.341 0.0158 0.33 -0.4037 -0.4203 1053080 IFLab1_004151 OC(C(O)c1ccccc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M16 compound treatment 0.332 0.00706 0.28 0.337 0.0118 0.25 0.3711 0.9983 2067825 IFLab1_004152 COC(=O)c1ccc(CSC(=S)N(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M17 compound treatment 0.331 0.00606 0.24 0.335 0.00981 0.21 0.3137 0.9972 1189581 IFLab1_004153 CC(=O)Nc1ccc(c(c1)C(=O)O)n2c(C)ccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M18 compound treatment 0.365 0.0401 1.58 0.367 0.0418 0.87 1.7325 0.9615 2067826 IFLab1_004154 Fc1ccc(cc1)C(=O)CC(c2cccs2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M19 compound treatment 0.31 -0.0149 -0.59 0.316 -0.00919 -0.19 -0.5512 -0.892 1393870 IFLab1_004155 Oc1c(C(=O)Nc2nccs2)c(=O)[nH]c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M20 compound treatment 0.328 0.00306 0.12 0.335 0.00981 0.21 0.2303 0.9677 2067827 IFLab1_004156 CNC(=O)/C=C/c1cccc(c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M21 compound treatment 0.342 0.0171 0.67 0.322 -0.00319 -0.07 0.4272 0.6337 2067828 IFLab1_004157 CC(C)n1c(CCCO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M22 compound treatment 0.336 0.0111 0.43 0.347 0.0218 0.46 0.6303 0.9997 2067829 IFLab1_004158 COC(=O)c1ccc(cc1)N2C(=O)/C(=C\c3cccnc3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M23 mock treatment 0.291 -0.0339 -1.33 0.334 0.00881 0.18 -0.8131 -0.6036 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 M24 positive control 0.087 -0.238 -9.36 0.091 -0.234 -4.9 -10.0804 -0.9545 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N01 compound treatment 0.325 6.25E-5 0.0 0.325 -1.88E-4 0.0 -0.001 -0.224 2067830 IFLab1_004159 Clc1ccc(cc1)C(=O)N2CCCCCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N02 compound treatment 0.376 0.0511 2.01 0.371 0.0458 0.96 2.0975 0.9428 2067831 IFLab1_004160 CCc1ccc(/C=C/2\SC(=S)N(CCC(=O)NCCCN3CCOCC3)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N03 compound treatment 0.341 0.0161 0.63 0.335 0.00981 0.21 0.5918 0.8911 2067832 IFLab1_004161 COc1ccc(/C=C/2\CN(C)C/C(=C/c3ccc(OC)c(OC)c3)/C2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N04 compound treatment 0.384 0.0591 2.32 0.384 0.0588 1.23 2.5123 0.9559 1742089 IFLab1_004162 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc4OCCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N05 compound treatment 0.326 0.00106 0.04 0.331 0.00581 0.12 0.1155 0.8985 2067833 IFLab1_004163 O=C(CSc1ncnc2sc3CCCCc3c12)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N06 compound treatment 0.337 0.0121 0.47 0.334 0.00881 0.18 0.4658 0.9153 1592722 IFLab1_004164 CCOc1ccc2n3C(=O)CC(Sc3nc2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N07 compound treatment 0.318 -0.00694 -0.27 0.33 0.00481 0.1 -0.1217 -0.4184 1324779 IFLab1_004165 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N08 compound treatment 0.347 0.0221 0.87 0.341 0.0158 0.33 0.8474 0.9127 1404106 IFLab1_004166 O=C1CC(Sc2nc(nn12)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N09 compound treatment 0.346 0.0211 0.83 0.324 -0.00119 -0.02 0.568 0.6856 1330345 IFLab1_004167 CC(C)(C)NC1C(NS(=O)(=O)c2ccccc2)c3cccc4cccc1c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N10 compound treatment 0.342 0.0171 0.67 0.337 0.0118 0.25 0.6492 0.908 1362202 IFLab1_004168 Cc1cc(C)n(n1)C(=O)CCNC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N11 compound treatment 0.347 0.0221 0.87 0.346 0.0208 0.44 0.9213 0.9492 1475361 IFLab1_004169 C(Sc1nc2ccccc2o1)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N12 compound treatment 0.346 0.0211 0.83 0.356 0.0308 0.64 1.0415 0.9923 1562660 IFLab1_004170 CCCc1n[nH]c2OC(=C(C#N)C(C3CCC=CC3)c12)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N13 compound treatment 0.373 0.0481 1.89 0.37 0.0448 0.94 1.9993 0.9477 1272545 IFLab1_004171 COc1ccc(cc1OC)c2ncc3ccccn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N14 compound treatment 0.333 0.00806 0.32 0.327 0.00181 0.04 0.251 0.7861 1158072 IFLab1_004172 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2cccs2)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N15 compound treatment 0.327 0.00206 0.08 0.315 -0.0102 -0.21 -0.0934 -0.4095 1297657 IFLab1_004173 CC1(C)C(OCC(O)CN2CCN(CC2)c3ccccc3F)C4(C)CCC1C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N16 compound treatment 0.361 0.0361 1.42 0.367 0.0418 0.87 1.6213 0.9731 1609604 IFLab1_004174 Nc1nc(SC2CCCCC2=O)c(C#N)c(c1C#N)c3ccc(O)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N17 compound treatment 0.329 0.00406 0.16 0.33 0.00481 0.1 0.1842 0.9753 1361801 IFLab1_004175 CCOC(=O)N1CCN(CC(O)COc2ccccc2CC=C)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N18 compound treatment 0.373 0.0481 1.89 0.358 0.0328 0.69 1.8218 0.9061 1452225 IFLab1_004176 CCOc1ccc(cc1)c2nc3ccc(C)cc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N19 compound treatment 0.345 0.0201 0.79 0.34 0.0148 0.31 0.777 0.9167 1481685 IFLab1_004177 CCc1ccc(OCC(O)CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N20 compound treatment 0.327 0.00206 0.08 0.326 8.12E-4 0.02 0.0694 0.8372 2067834 IFLab1_004178 Clc1cccc(c1)C(=O)Sc2nnnn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N21 compound treatment 0.343 0.0181 0.71 0.345 0.0198 0.41 0.7953 0.9672 1166709 IFLab1_004179 COc1ccc(CCNC(=O)CSc2nc(N)c3c(C)c(C)sc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N22 compound treatment 0.341 0.0161 0.63 0.335 0.00981 0.21 0.5918 0.8911 2067835 IFLab1_004180 CCSc1nnc2sc3ccccc3n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N23 mock treatment 0.33 0.00506 0.2 0.331 0.00581 0.12 0.2268 0.9721 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 N24 positive control 0.088 -0.237 -9.32 0.091 -0.234 -4.9 -10.0526 -0.955 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O01 compound treatment 0.326 0.00106 0.04 0.318 -0.00719 -0.15 -0.0768 -0.4921 1589629 IFLab1_004181 CCOC(=O)c1oc2ccccc2c1NC(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O02 compound treatment 0.314 -0.0109 -0.43 0.309 -0.0162 -0.34 -0.5436 -0.993 1289953 IFLab1_004182 CCc1nc2ccccc2n1C(=O)c3ccccc3C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O03 compound treatment 0.317 -0.00794 -0.31 0.316 -0.00919 -0.19 -0.3566 -0.9729 2067836 IFLab1_004183 CCOC(=O)c1oc2ccccc2c1NC(=O)CCSc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O04 compound treatment 0.311 -0.0139 -0.55 0.312 -0.0132 -0.28 -0.5826 -0.9496 2067837 IFLab1_004184 CCCn1c(nc2ccccc12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O05 compound treatment 0.314 -0.0109 -0.43 0.308 -0.0172 -0.36 -0.5584 -0.9961 1731872 IFLab1_004185 COc1ccc(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O06 compound treatment 0.29 -0.0349 -1.37 0.292 -0.0332 -0.69 -1.4624 -0.9501 1148178 IFLab1_004186 OP(=O)(c1nc2CCCCc2s1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O07 compound treatment 0.328 0.00306 0.12 0.319 -0.00619 -0.13 -0.0064 -0.0363 1428100 IFLab1_004187 CC1(C)C2(C)CCC1(CC2=O)C(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O08 compound treatment 0.377 0.0521 2.05 0.38 0.0548 1.15 2.2585 0.9625 2067838 IFLab1_004188 CC(=O)Nc1ccc(/N=C/c2ccc(OC(=O)c3cccnc3)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O09 compound treatment 0.327 0.00206 0.08 0.314 -0.0112 -0.23 -0.1082 -0.4367 1699037 IFLab1_004189 O=C(c1ccco1)c2ncc[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O10 compound treatment 0.333 0.00806 0.32 0.331 0.00581 0.12 0.3102 0.9135 1168461 IFLab1_004190 OC1CSC(=S)N1Cc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O11 compound treatment 0.328 0.00306 0.12 0.331 0.00581 0.12 0.1712 1.0 1285740 IFLab1_004191 C(Cc1nc2ccccc2s1)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O12 compound treatment 0.347 0.0221 0.87 0.342 0.0168 0.35 0.8622 0.921 1593851 IFLab1_004192 CCOC(=O)c1sc(Nc2ccccc2)nc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O13 compound treatment 0.342 0.0171 0.67 0.337 0.0118 0.25 0.6492 0.908 1231987 IFLab1_004193 COc1ccc2cc(Br)ccc2c1CC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O14 compound treatment 0.377 0.0521 2.05 0.388 0.0628 1.31 2.3769 0.9771 1572467 IFLab1_004194 COC(=O)c1ccc(CSc2nc3ccccc3c(=O)[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O15 compound treatment 0.322 -0.00294 -0.12 0.339 0.0138 0.29 0.1227 0.3943 2067839 IFLab1_004195 COC(=O)CC1SCCNC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O16 compound treatment 0.34 0.0151 0.59 0.336 0.0108 0.23 0.5788 0.9129 2067840 IFLab1_004196 COC(=O)c1ccc(CSC(=N)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O17 compound treatment 0.331 0.00606 0.24 0.325 -1.88E-4 0.0 0.1658 0.6954 1621447 IFLab1_004197 Nc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O18 compound treatment 0.338 0.0131 0.51 0.345 0.0198 0.41 0.6563 0.9944 2067841 IFLab1_004198 Clc1ccc(cc1)C(=O)CC(c2ccco2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O19 compound treatment 0.345 0.0201 0.79 0.344 0.0188 0.39 0.8361 0.9484 2067842 IFLab1_004199 C(Sc1nc2ccccc2[nH]1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O20 compound treatment 0.359 0.0341 1.34 0.362 0.0368 0.77 1.4917 0.9655 2067843 IFLab1_004200 O=C(/N=C/1\SCC(=O)N1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O21 compound treatment 0.34 0.0151 0.59 0.343 0.0178 0.37 0.6823 0.9751 1090872 IFLab1_004201 OC(=O)c1ccccc1c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O22 compound treatment 0.343 0.0181 0.71 0.343 0.0178 0.37 0.7657 0.9547 2067844 IFLab1_004202 Cc1ccc(cc1)c2csc3ncnc(SCCC(=O)O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O23 mock treatment 0.325 6.25E-5 0.0 0.329 0.00381 0.08 0.0582 0.7285 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 O24 positive control 0.09 -0.235 -9.24 0.094 -0.231 -4.84 -9.9526 -0.9545 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P01 compound treatment 0.331 0.00606 0.24 0.338 0.0128 0.27 0.3581 0.9983 1639547 IFLab1_004203 CC1CN(CCC(=O)Nc2ccc3OCCOc3c2)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P02 compound treatment 0.314 -0.0109 -0.43 0.314 -0.0112 -0.23 -0.4696 -0.9591 1517519 IFLab1_004204 CC(C)(C)c1csc(NC(=O)c2ccc3OCCOc3c2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P03 compound treatment 0.33 0.00506 0.2 0.328 0.00281 0.06 0.1824 0.8786 1499175 IFLab1_004205 CCN(CC)C(=S)SC1CCCCN(C(=O)c2ccc(F)cc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P04 compound treatment 0.349 0.0241 0.95 0.353 0.0278 0.58 1.0805 0.9728 1662741 IFLab1_004206 CCOC(=O)c1sc2ccccc2c1NC(=O)c3coc4ccccc4c3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P05 compound treatment 0.348 0.0231 0.91 0.352 0.0268 0.56 1.0379 0.9734 1611338 IFLab1_004207 COc1ccc(cc1NC(=O)C)S(=O)(=O)Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P06 compound treatment 0.353 0.0281 1.1 0.361 0.0358 0.75 1.3101 0.9822 1678592 IFLab1_004208 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P07 compound treatment 0.406 0.0811 3.19 0.388 0.0628 1.31 3.1831 0.9233 1717784 IFLab1_004209 Cc1cc(NC(=O)c2ccc(cc2)C(=O)c3ccccc3)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P08 compound treatment 0.363 0.0381 1.5 0.359 0.0338 0.71 1.5585 0.9415 1170257 IFLab1_004210 O=C(NCc1ccc2OCOc2c1)C3(CC3)S(=O)(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P09 compound treatment 0.352 0.0271 1.06 0.354 0.0288 0.6 1.1787 0.9638 1480904 IFLab1_004211 CC(C)(C)c1ccc(NC(=O)C2CCCCN2S(=O)(=O)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P10 compound treatment 0.358 0.0331 1.3 0.37 0.0448 0.94 1.5823 0.9872 1608487 IFLab1_004212 CCOC(=O)C1=C(OC(=C(C#N)C1CC(C)C)N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P11 compound treatment 0.362 0.0371 1.46 0.357 0.0318 0.67 1.5011 0.937 1518616 IFLab1_004213 Clc1cccc(NCc2cn3ccccc3n2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P12 compound treatment 0.365 0.0401 1.58 0.376 0.0508 1.06 1.8657 0.9817 2067845 IFLab1_004214 CCC(C)C1C(=C(N)Oc2[nH]nc(C)c12)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P13 compound treatment 0.359 0.0341 1.34 0.363 0.0378 0.79 1.5065 0.9685 1065279 IFLab1_004215 CN1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P14 compound treatment 0.332 0.00706 0.28 0.335 0.00981 0.21 0.3415 0.989 1599312 IFLab1_004216 CC1=C(C(C(=C(N1)SCC(=O)O)C#N)c2cccs2)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P15 compound treatment 0.347 0.0221 0.87 0.34 0.0148 0.31 0.8326 0.9038 1350007 IFLab1_004217 OC(COc1ccccc1CC=C)CN2CCN(CC2)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P16 compound treatment 0.356 0.0311 1.22 0.362 0.0368 0.77 1.4083 0.9753 1151769 IFLab1_004218 N#CC(=C1CCCC1)c2nc(cs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P17 compound treatment 0.349 0.0241 0.95 0.348 0.0228 0.48 1.0065 0.9498 1573234 IFLab1_004219 CCOC(=O)N1CCN(CC(O)COc2ccc(cc2)C3CCCCC3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P18 compound treatment 0.358 0.0331 1.3 0.351 0.0258 0.54 1.3012 0.9243 2067846 IFLab1_004220 Cc1ccc2nc(NC(=O)c3ccccc3C(=O)O)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P19 compound treatment 0.358 0.0331 1.3 0.355 0.0298 0.62 1.3603 0.9434 1192690 IFLab1_004221 OC(=O)c1cccc(c1)c2ccc(O)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P20 compound treatment 0.346 0.0211 0.83 0.354 0.0288 0.6 1.0119 0.9878 1585548 IFLab1_004222 COc1cccc(c1)C(=O)SC2=NCCS2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P21 compound treatment 0.352 0.0271 1.06 0.351 0.0258 0.54 1.1343 0.9506 2067847 IFLab1_004223 Cc1sc2nc(SCC(=O)NCCO)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P22 compound treatment 0.349 0.0241 0.95 0.343 0.0178 0.37 0.9326 0.9171 1284329 IFLab1_004224 O=C(Oc1ccc2c3CCCCc3c(=O)oc2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P23 mock treatment 0.34 0.0151 0.59 0.34 0.0148 0.31 0.6379 0.9544 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1423 P24 positive control 0.093 -0.232 -9.12 0.098 -0.227 -4.75 -9.81 -0.9539 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A01 compound treatment 0.345 0.0219 0.86 0.344 0.0193 0.4 0.8957 0.9403 1612472 IFLab1_004225 Cc1ccc(cc1)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A02 compound treatment 0.329 0.00594 0.23 0.341 0.0163 0.34 0.4065 0.9828 1493512 IFLab1_004226 Cc1ccccc1CN2C(=O)C(O)(CC(=O)c3ccc(N)cc3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A03 compound treatment 0.323 -6.25E-5 0.0 0.321 -0.00369 -0.08 -0.0563 -0.7293 1393816 IFLab1_004227 COc1ccc(cc1OC)C(=O)Oc2ccc3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A04 compound treatment 0.357 0.0339 1.33 0.355 0.0303 0.63 1.3921 0.9422 2067848 IFLab1_004228 NS(=O)(=O)c1cc(ccc1F)C(=O)Nc2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A05 compound treatment 0.327 0.00394 0.15 0.324 -6.88E-4 -0.01 0.0993 0.6386 2067849 IFLab1_004229 Cc1ccc(cc1)S(=O)(=O)/N=C(/N)\c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A06 compound treatment 0.324 9.38E-4 0.04 0.326 0.00131 0.03 0.0455 0.9895 1141228 IFLab1_004230 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCCN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A07 compound treatment 0.329 0.00594 0.23 0.329 0.00431 0.09 0.2289 0.9145 1004437 IFLab1_004231 Nc1ccc(cc1)c2ccc(N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A08 compound treatment 0.358 0.0349 1.37 0.355 0.0303 0.63 1.4199 0.9384 2067850 IFLab1_004232 Fc1ccccc1CSCCC(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A09 compound treatment 0.323 -6.25E-5 0.0 0.326 0.00131 0.03 0.0177 0.6413 2067851 IFLab1_004233 CCCn1c(CCCNC(=O)c2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A10 compound treatment 0.325 0.00194 0.08 0.334 0.00931 0.19 0.1917 0.916 1320853 IFLab1_004234 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A11 compound treatment 0.329 0.00594 0.23 0.32 -0.00469 -0.1 0.0957 0.378 2067852 IFLab1_004235 CC(C)Cc1nc2ccccc2n1CC(=C)Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A12 compound treatment 0.329 0.00594 0.23 0.35 0.0253 0.53 0.5396 0.9322 1356380 IFLab1_004236 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCOCC4)c(C)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A13 compound treatment 0.35 0.0269 1.06 0.332 0.00731 0.15 0.8571 0.801 1777377 IFLab1_004237 OC(=O)C1CCCN1S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A14 compound treatment 0.376 0.0529 2.08 0.367 0.0423 0.89 2.0979 0.9275 1213553 IFLab1_004238 CN(C)c1ccc(cc1)C(O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A15 compound treatment 0.328 0.00494 0.19 0.338 0.0133 0.28 0.3343 0.9844 2067853 IFLab1_004239 CCOC(=O)CSc1nc(C)c2ccc(C)cc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A16 compound treatment 0.343 0.0199 0.78 0.344 0.0193 0.4 0.8401 0.9525 2067854 IFLab1_004240 Cc1cccc(NC(=O)CCCN2C(=O)/C(=C/c3cccs3)/SC2=S)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A17 compound treatment 0.334 0.0109 0.43 0.353 0.0283 0.59 0.723 0.9876 1585819 IFLab1_004241 Cc1ccccc1NC(=O)CSc2nc3ccc(N)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A18 compound treatment 0.343 0.0199 0.78 0.327 0.00231 0.05 0.5885 0.7493 2067855 IFLab1_004242 Brc1cccc(/N=C/c2ccc(OC(=O)c3ccccn3)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A19 compound treatment 0.328 0.00494 0.19 0.329 0.00431 0.09 0.2011 0.9393 1213026 IFLab1_004243 CCC(C)NS(=O)(=O)c1cccc2nsnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A20 compound treatment 0.322 -0.00106 -0.04 0.347 0.0223 0.47 0.3006 0.6413 1179632 IFLab1_004244 Cc1sc2nc(SC3CCOC3=O)[nH]c(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A21 compound treatment 0.314 -0.00906 -0.36 0.327 0.00231 0.05 -0.2177 -0.6055 1582509 IFLab1_004245 CCCOc1ccc(cc1OC)C(=O)NCC2COc3ccccc3O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A22 compound treatment 0.352 0.0289 1.14 0.326 0.00131 0.03 0.8239 0.724 1015772 IFLab1_004246 OCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A23 mock treatment 0.318 -0.00506 -0.2 0.34 0.0153 0.32 0.0858 0.2275 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 A24 positive control 0.079 -0.244 -9.6 0.08 -0.245 -5.12 -10.4061 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B01 compound treatment 0.385 0.0619 2.44 0.402 0.0773 1.62 2.866 0.9803 2067856 IFLab1_004247 COc1ccc(cc1)c2nnc(SCC(=O)c3ccc(Cl)cc3)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B02 compound treatment 0.352 0.0289 1.14 0.364 0.0393 0.82 1.3862 0.9873 1595456 IFLab1_004248 CCC(CO)NCC(O)CN1c2ccccc2Sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B03 compound treatment 0.321 -0.00206 -0.08 0.324 -6.88E-4 -0.01 -0.0675 -0.8198 2067857 IFLab1_004249 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B04 compound treatment 0.323 -6.25E-5 0.0 0.327 0.00231 0.05 0.0325 0.6703 1435499 IFLab1_004250 Cc1nc2ccccc2n1CC(O)COc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B05 compound treatment 0.319 -0.00406 -0.16 0.317 -0.00769 -0.16 -0.2267 -1.0 2067858 IFLab1_004251 Cc1ccc(SCC(=O)N2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B06 compound treatment 0.339 0.0159 0.63 0.344 0.0193 0.4 0.7289 0.9775 1629445 IFLab1_004252 OCc1nc2ccccc2n1CC(O)COc3ccc(OCc4ccccc4)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B07 compound treatment 0.328 0.00494 0.19 0.326 0.00131 0.03 0.1567 0.7992 1490604 IFLab1_004253 CCOC(=O)N1CCN(CC1)C(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B08 compound treatment 0.326 0.00294 0.12 0.331 0.00631 0.13 0.1751 0.9978 1513930 IFLab1_004254 Clc1ccc(OC(=O)N2CCCCC2)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B09 compound treatment 0.33 0.00694 0.27 0.334 0.00931 0.19 0.3307 0.9864 1565645 IFLab1_004255 Fc1ccc(NC(=O)CSC2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B10 compound treatment 0.323 -6.25E-5 0.0 0.321 -0.00369 -0.08 -0.0563 -0.7293 2067859 IFLab1_004256 CCOC(=O)N=c1oc2ccccc2o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B11 compound treatment 0.346 0.0229 0.9 0.334 0.00931 0.19 0.7755 0.8405 1329469 IFLab1_004257 O=C(CSCc1ccco1)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B12 compound treatment 0.33 0.00694 0.27 0.33 0.00531 0.11 0.2715 0.9217 2067860 IFLab1_004258 CCOC(=O)Cc1nc(O)cs1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B13 compound treatment 0.387 0.0639 2.51 0.392 0.0673 1.41 2.7736 0.9625 2067861 IFLab1_004259 Oc1c(Br)cc(Br)cc1/C=N/c2ccccc2F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B14 compound treatment 0.318 -0.00506 -0.2 0.335 0.0103 0.22 0.0118 0.0404 1601596 IFLab1_004260 Clc1cc2CN(COc2c3ncccc13)C4CCS(=O)(=O)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B15 compound treatment 0.33 0.00694 0.27 0.343 0.0183 0.38 0.4638 0.9861 1602324 IFLab1_004261 COc1ccc2oc(=O)c(cc2c1)C(=O)NC3=C(CCC3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B16 compound treatment 0.327 0.00394 0.15 0.337 0.0123 0.26 0.2917 0.9703 1586226 IFLab1_004262 COc1ccc(OCC(O)CN2CCc3ccccc3C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B17 compound treatment 0.372 0.0489 1.92 0.373 0.0483 1.01 2.0754 0.9549 1918439 IFLab1_004263 CCOc1ccc(/N=C/c2ccc(cc2O)N(CC)CC)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B18 compound treatment 0.33 0.00694 0.27 0.345 0.0203 0.43 0.4934 0.977 1291626 IFLab1_004264 O=S(=O)(NC1CCCCC1NCc2ccco2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B19 compound treatment 0.339 0.0159 0.63 0.338 0.0133 0.28 0.6401 0.9334 1722803 IFLab1_004265 COc1ccc(c2ccccc12)S(=O)(=O)NCc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B20 compound treatment 0.335 0.0119 0.47 0.342 0.0173 0.36 0.5881 0.9918 1200025 IFLab1_004266 Brc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ncnn24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B21 compound treatment 0.339 0.0159 0.63 0.328 0.00331 0.07 0.4921 0.7806 1376706 IFLab1_004267 COc1ccc(OC)c(c1)S(=O)(=O)NC(C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B22 compound treatment 0.328 0.00494 0.19 0.333 0.00831 0.17 0.2603 0.9985 1417127 IFLab1_004268 COc1ccccc1NC(=O)c2c(C)nc3ccccc3c2C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B23 mock treatment 0.324 9.38E-4 0.04 0.326 0.00131 0.03 0.0455 0.9895 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 B24 positive control 0.078 -0.245 -9.64 0.079 -0.246 -5.14 -10.4487 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C01 compound treatment 0.339 0.0159 0.63 0.349 0.0243 0.51 0.8028 0.9947 2067862 IFLab1_004269 CN(C)C(C#N)c1c[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C02 compound treatment 0.33 0.00694 0.27 0.335 0.0103 0.22 0.3455 0.9933 1399619 IFLab1_004270 Cc1ccc(cc1NC(=O)c2ccc(F)cc2)c3nc4ncccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C03 compound treatment 0.321 -0.00206 -0.08 0.323 -0.00169 -0.04 -0.0823 -0.9306 1145310 IFLab1_004271 COC(=O)c1c(C)n2CCCc2c1C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C04 compound treatment 0.336 0.0129 0.51 0.34 0.0153 0.32 0.5863 0.9752 1401068 IFLab1_004272 Cc1ccc(NC(=O)c2ccc(F)c(c2)S(=O)(=O)N3CCCC3)cc1F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C05 compound treatment 0.331 0.00794 0.31 0.332 0.00731 0.15 0.3289 0.9462 1244776 IFLab1_004273 CC(C)(C)C(=O)NS(=O)(=O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C06 compound treatment 0.334 0.0109 0.43 0.339 0.0143 0.3 0.5159 0.9844 1257119 IFLab1_004274 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C07 compound treatment 0.324 9.38E-4 0.04 0.334 0.00931 0.19 0.1639 0.8262 1221558 IFLab1_004275 COc1ccccc1N2CCN(Cc3cc(Cl)c(O)c4ncccc34)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C08 compound treatment 0.337 0.0139 0.55 0.339 0.0143 0.3 0.5993 0.9596 1215843 IFLab1_004276 COc1ccc(CNC(=O)CSCc2ccccc2F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C09 compound treatment 0.338 0.0149 0.59 0.34 0.0153 0.32 0.6419 0.9594 2067863 IFLab1_004277 C1COc2cc(ccc2O1)C3=Nn4cnnc4SC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C10 compound treatment 0.352 0.0289 1.14 0.344 0.0193 0.4 1.0903 0.903 1311268 IFLab1_004278 CC1=C(C(C2=C(CCCC2=O)N1)c3c(F)cccc3Cl)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C11 compound treatment 0.338 0.0149 0.59 0.325 3.12E-4 0.01 0.4199 0.7149 2067864 IFLab1_004279 CC(C)c1nc2ccccc2n1CC(=C)Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C12 compound treatment 0.327 0.00394 0.15 0.34 0.0153 0.32 0.3361 0.9443 1436807 IFLab1_004280 CCCNC(=O)c1ccc2n(cnc2c1)c3ccccc3OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C13 compound treatment 0.343 0.0199 0.78 0.338 0.0133 0.28 0.7513 0.9031 1247600 IFLab1_004281 O=c1oc(nc2ccccc12)c3ccc(cc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C14 compound treatment 0.337 0.0139 0.55 0.338 0.0133 0.28 0.5845 0.9508 1851046 IFLab1_004282 OCc1ccc(O)c2ncccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C15 compound treatment 0.335 0.0119 0.47 0.337 0.0123 0.26 0.5141 0.9601 1133645 IFLab1_004283 COC(=O)CC1(O)N(Cc2ccccc2)C(=O)c3ccccc31 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C16 compound treatment 0.364 0.0409 1.61 0.355 0.0303 0.63 1.5867 0.9171 2067865 IFLab1_004284 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(Cc3ccccc3)C(C)(C)C)C2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C17 compound treatment 0.334 0.0109 0.43 0.339 0.0143 0.3 0.5159 0.9844 1667144 IFLab1_004285 O=C(c1ccco1)c2nnn(Cc3ccccc3)c2c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C18 compound treatment 0.337 0.0139 0.55 0.327 0.00231 0.05 0.4217 0.7666 2067866 IFLab1_004286 Brc1cccc(/N=C/c2ccc(OC(=O)c3ccncc3)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C19 compound treatment 0.327 0.00394 0.15 0.325 3.12E-4 0.01 0.1141 0.7363 1580942 IFLab1_004287 COc1ccccc1CNC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCC(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C20 compound treatment 0.318 -0.00506 -0.2 0.34 0.0153 0.32 0.0858 0.2275 1053978 IFLab1_004288 OC(=O)CCNc1ccccc1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C21 compound treatment 0.335 0.0119 0.47 0.346 0.0213 0.45 0.6472 0.9997 1151524 IFLab1_004289 Brc1ccccc1C(=O)NCC2OCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C22 compound treatment 0.333 0.00994 0.39 0.323 -0.00169 -0.04 0.2513 0.6406 1377098 IFLab1_004290 Oc1nc2ccccc2nc1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C23 mock treatment 0.32 -0.00306 -0.12 0.32 -0.00469 -0.1 -0.1545 -0.9948 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 C24 positive control 0.078 -0.245 -9.64 0.078 -0.247 -5.16 -10.4635 -0.9572 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D01 compound treatment 0.345 0.0219 0.86 0.347 0.0223 0.47 0.9401 0.9585 1642800 IFLab1_004291 O=S(=O)(NC1CCS(=O)(=O)C1)c2cccc3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D02 compound treatment 0.317 -0.00606 -0.24 0.333 0.00831 0.17 -0.0455 -0.1544 1578807 IFLab1_004292 OCCN1CCN(CC1)C(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D03 compound treatment 0.329 0.00594 0.23 0.333 0.00831 0.17 0.2881 0.9895 1428593 IFLab1_004293 Cc1cc(=O)cc(C)n1c2ccc(O)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D04 compound treatment 0.31 -0.0131 -0.51 0.317 -0.00769 -0.16 -0.4769 -0.8861 2067867 IFLab1_004294 CC(C)c1cc(C(C)C)c(cc1NC(=O)C)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D05 compound treatment 0.341 0.0179 0.71 0.347 0.0223 0.47 0.8289 0.9799 2067868 IFLab1_004295 O=C(CSC1CCCCC1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D06 compound treatment 0.349 0.0259 1.02 0.35 0.0253 0.53 1.0957 0.9534 1118201 IFLab1_004296 CC(=O)N1CCN(CC(O)COc2ccc(OCc3ccccc3)cc2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D07 compound treatment 0.338 0.0149 0.59 0.338 0.0133 0.28 0.6123 0.9419 1708765 IFLab1_004297 O=C(CSC1=NCCS1)N2CCC(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D08 compound treatment 0.338 0.0149 0.59 0.339 0.0143 0.3 0.6271 0.9512 1204115 IFLab1_004298 CN(C)C(=O)Oc1ccc(Cl)c2cccnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D09 compound treatment 0.532 0.209 8.21 0.509 0.184 3.86 8.5362 0.9406 1712972 IFLab1_004299 COc1ccc(NC(=O)CSC2=NCCS2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D10 compound treatment 0.374 0.0509 2.0 0.36 0.0353 0.74 1.9387 0.9082 2067869 IFLab1_004300 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCC(=O)Nc3ccccc3O)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D11 compound treatment 0.355 0.0319 1.26 0.355 0.0303 0.63 1.3365 0.95 2067870 IFLab1_004301 O=C(CSC1=NCCS1)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D12 compound treatment 0.316 -0.00706 -0.28 0.324 -6.88E-4 -0.01 -0.2065 -0.7427 1198909 IFLab1_004302 Oc1c(ccc2cccnc12)C(N3CCCC3)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D13 compound treatment 0.393 0.0699 2.75 0.366 0.0413 0.86 2.5557 0.8866 2067871 IFLab1_004303 Oc1ccc(/C=N\c2sc3CCCCc3c2C#N)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D14 compound treatment 0.337 0.0139 0.55 0.338 0.0133 0.28 0.5845 0.9508 1184389 IFLab1_004304 OC(COc1ccc2CCCc2c1)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D15 compound treatment 0.334 0.0109 0.43 0.336 0.0113 0.24 0.4715 0.9604 1344107 IFLab1_004305 Fc1ccc(NC(=O)c2cc3cc(Cl)cc(Cl)c3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D16 compound treatment 0.335 0.0119 0.47 0.335 0.0103 0.22 0.4845 0.9378 1623111 IFLab1_004306 CC(C)n1c(NCCO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D17 compound treatment 0.338 0.0149 0.59 0.342 0.0173 0.36 0.6715 0.9731 1208439 IFLab1_004307 COc1cccc2cc(C(=O)N3CCCc4ccccc34)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D18 compound treatment 0.336 0.0129 0.51 0.338 0.0133 0.28 0.5567 0.9598 1445043 IFLab1_004308 CN(C)C1CCCCC1NS(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D19 compound treatment 0.344 0.0209 0.82 0.348 0.0233 0.49 0.9271 0.9688 1647688 IFLab1_004309 COc1ccc(c2ccccc12)S(=O)(=O)Nc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D20 compound treatment 0.338 0.0149 0.59 0.341 0.0163 0.34 0.6567 0.9667 1587839 IFLab1_004310 Fc1ccccc1C2C3=C(CCCC3=O)Nc4ncnn24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D21 compound treatment 0.341 0.0179 0.71 0.34 0.0153 0.32 0.7253 0.9363 1133679 IFLab1_004311 CCOc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D22 compound treatment 0.339 0.0159 0.63 0.362 0.0373 0.78 0.9952 0.9941 1219904 IFLab1_004312 CCOc1cc2SCC(=O)Nc2cc1C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D23 mock treatment 0.325 0.00194 0.08 0.325 3.12E-4 0.01 0.0585 0.765 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 D24 positive control 0.079 -0.244 -9.6 0.08 -0.245 -5.12 -10.4061 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E01 compound treatment 0.337 0.0139 0.55 0.334 0.00931 0.19 0.5253 0.9032 1512753 IFLab1_004313 COc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E02 compound treatment 0.321 -0.00206 -0.08 0.328 0.00331 0.07 -0.0083 -0.078 1169697 IFLab1_004314 Cc1nc2ccc(Cl)cc2c(O)c1CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E03 compound treatment 0.379 0.0559 2.2 0.384 0.0593 1.24 2.4328 0.9633 2067872 IFLab1_004315 COC(=O)/C=C/1\SC(=NC1=O)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E04 compound treatment 0.32 -0.00306 -0.12 0.332 0.00731 0.15 0.0231 0.1184 1505449 IFLab1_004316 COc1ccccc1NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E05 compound treatment 0.321 -0.00206 -0.08 0.334 0.00931 0.19 0.0805 0.3812 1650517 IFLab1_004317 OCCNC(=O)c1ccc(CSc2nc3ccccc3c(=O)[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E06 compound treatment 0.326 0.00294 0.12 0.337 0.0123 0.26 0.2639 0.9345 1690222 IFLab1_004318 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E07 compound treatment 0.333 0.00994 0.39 0.338 0.0133 0.28 0.4733 0.9863 1251542 IFLab1_004319 NC(=O)C1(CC1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E08 compound treatment 0.33 0.00694 0.27 0.33 0.00531 0.11 0.2715 0.9217 2067873 IFLab1_004320 Fc1cccc(CSCCC(=O)N2CCc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E09 compound treatment 0.349 0.0259 1.02 0.353 0.0283 0.59 1.1401 0.9666 2067874 IFLab1_004321 CC(C)(C)c1nnc2SCC(=Nn12)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E10 compound treatment 0.344 0.0209 0.82 0.345 0.0203 0.43 0.8827 0.9527 2067875 IFLab1_004322 Clc1ccccc1CSc2ncccc2C(=O)NCCCN3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E11 compound treatment 0.345 0.0219 0.86 0.346 0.0213 0.45 0.9253 0.9529 1330239 IFLab1_004323 COC(=O)c1ccc(OCC(O)CN2C(C)(C)CC(O)CC2(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E12 compound treatment 0.34 0.0169 0.67 0.345 0.0203 0.43 0.7715 0.9765 1169734 IFLab1_004324 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCc4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E13 compound treatment 0.343 0.0199 0.78 0.345 0.0203 0.43 0.8549 0.9587 1551497 IFLab1_004325 NC(=O)c1ccc(NC(=O)COc2cc(Cl)ccc2Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E14 compound treatment 0.338 0.0149 0.59 0.344 0.0193 0.4 0.7011 0.9834 2067876 IFLab1_004326 CN(C)C(=O)Cc1c[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E15 compound treatment 0.121 -0.202 -7.94 0.126 -0.199 -4.16 -8.5577 -0.9544 2067877 IFLab1_004327 O=C1C=CC(=O)N1CC(c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E16 compound treatment 0.334 0.0109 0.43 0.342 0.0173 0.36 0.5603 0.9964 1555179 IFLab1_004328 COc1ccc(OCc2nc3ccccc3n2CC=C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E17 compound treatment 0.332 0.00894 0.35 0.345 0.0203 0.43 0.549 0.9955 1719407 IFLab1_004329 NS(=O)(=O)c1cccc(c1)C(=O)N2CCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E18 compound treatment 0.339 0.0159 0.63 0.346 0.0213 0.45 0.7585 0.9861 2067878 IFLab1_004330 COc1cc(/C=N/c2ccc(NC(=O)C)cc2)ccc1OC(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E19 compound treatment 0.341 0.0179 0.71 0.345 0.0203 0.43 0.7993 0.9706 1656405 IFLab1_004331 COc1cccc(CSCC(=O)NCc2ccccc2Cl)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E20 compound treatment 0.348 0.0249 0.98 0.346 0.0213 0.45 1.0087 0.9364 2067879 IFLab1_004332 O/N=C/1\C(=O)N(Cc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E21 compound treatment 0.341 0.0179 0.71 0.346 0.0213 0.45 0.8141 0.9756 1985559 IFLab1_004333 Nc1nc(N)n(n1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E22 compound treatment 0.349 0.0259 1.02 0.351 0.0263 0.55 1.1105 0.9582 2067880 IFLab1_004334 COC(=O)c1cccc2/C(=N/O)/C(=O)Nc21 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E23 mock treatment 0.319 -0.00406 -0.16 0.319 -0.00569 -0.12 -0.1971 -0.9895 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 E24 positive control 0.081 -0.242 -9.52 0.085 -0.24 -5.02 -10.2765 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F01 compound treatment 0.34 0.0169 0.67 0.339 0.0143 0.3 0.6827 0.9349 1326153 IFLab1_004335 COc1ccc(cc1)c2nc3SC(CC(=O)n3n2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F02 compound treatment 0.354 0.0309 1.22 0.364 0.0393 0.82 1.4418 0.9819 1162856 IFLab1_004336 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CNCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F03 compound treatment 0.316 -0.00706 -0.28 0.316 -0.00869 -0.18 -0.3249 -0.9789 1138912 IFLab1_004337 Cc1cc(=O)cc(C)n1c2ccccc2O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F04 compound treatment 0.337 0.0139 0.55 0.347 0.0223 0.47 0.7177 0.9968 1439026 IFLab1_004338 OC(COc1ccccc1CC=C)Cn2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F05 compound treatment 0.317 -0.00606 -0.24 0.321 -0.00369 -0.08 -0.2231 -0.8905 2067881 IFLab1_004339 Cn1cnnc1SCC(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F06 compound treatment 0.339 0.0159 0.63 0.364 0.0393 0.82 1.0248 0.991 1641305 IFLab1_004340 OC(CNCc1ccccc1)Cn2c3CCCCc3c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F07 compound treatment 0.326 0.00294 0.12 0.329 0.00431 0.09 0.1455 0.9926 1306960 IFLab1_004341 O=C(CSC1CCCCC1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F08 compound treatment 0.339 0.0159 0.63 0.35 0.0253 0.53 0.8176 0.9965 2067882 IFLab1_004342 CCN(CC)C(=O)Oc1ccc2ccccc2c1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F09 compound treatment 0.331 0.00794 0.31 0.343 0.0183 0.38 0.4917 0.9948 1441301 IFLab1_004343 CCOc1ccc(NC(=O)CSC2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F10 compound treatment 0.328 0.00494 0.19 0.336 0.0113 0.24 0.3047 0.9951 1317691 IFLab1_004344 Nc1nc(SCC(=O)NCc2ccccn2)nc3sc4CCCCc4c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F11 compound treatment 0.335 0.0119 0.47 0.344 0.0193 0.4 0.6177 0.9972 2067883 IFLab1_004345 CCSc1nnc(NC(=O)CSc2ncccn2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F12 compound treatment 0.283 -0.0401 -1.58 0.272 -0.0527 -1.1 -1.8934 -0.9848 1124758 IFLab1_004346 CC1CCN(CC1)C(c2ccccc2)c3ccc4cccnc4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F13 compound treatment 0.347 0.0239 0.94 0.356 0.0313 0.66 1.1288 0.9843 2067884 IFLab1_004347 COc1ccc(/N=C/c2cc(Br)ccc2O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F14 compound treatment 0.354 0.0309 1.22 0.349 0.0243 0.51 1.2199 0.9252 1176626 IFLab1_004348 CCN1CCN(CC(O)COc2ccc3CCCc3c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F15 compound treatment 0.35 0.0269 1.06 0.376 0.0513 1.07 1.5082 1.0 2067885 IFLab1_004349 COc1ccc(O)c(/C=N/c2cc(C)ccn2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F16 compound treatment 0.347 0.0239 0.94 0.351 0.0263 0.55 1.0549 0.9674 1676471 IFLab1_004350 CCCc1nc2ccccc2n1C(=O)CCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F17 compound treatment 0.386 0.0629 2.47 0.396 0.0713 1.49 2.805 0.9707 2067886 IFLab1_004351 COc1cccc(/C=N/CCN2CCOCC2)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F18 compound treatment 0.348 0.0249 0.98 0.352 0.0273 0.57 1.0975 0.967 1442728 IFLab1_004352 O=S(=O)(NC1CCCCC1Nc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F19 compound treatment 0.342 0.0189 0.74 0.349 0.0243 0.51 0.8863 0.9828 1347669 IFLab1_004353 CC(=O)Nc1ccc(NC(=O)C2CC(=CCC2C(=O)O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F20 compound treatment 0.336 0.0129 0.51 0.337 0.0123 0.26 0.5419 0.9503 1571146 IFLab1_004354 COc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ncnn24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F21 compound treatment 0.343 0.0199 0.78 0.347 0.0223 0.47 0.8845 0.9694 1283413 IFLab1_004355 COc1c(Cl)c(Cl)ccc1S(=O)(=O)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F22 compound treatment 0.336 0.0129 0.51 0.343 0.0183 0.38 0.6307 0.9903 2067887 IFLab1_004356 CCc1cc2c(SCC(=O)c3ccccc3)ncnc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F23 mock treatment 0.321 -0.00206 -0.08 0.321 -0.00369 -0.08 -0.1119 -0.9997 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 F24 positive control 0.081 -0.242 -9.52 0.086 -0.239 -4.99 -10.2617 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G01 compound treatment 0.329 0.00594 0.23 0.331 0.00631 0.13 0.2585 0.9636 1263425 IFLab1_004357 COc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)NC(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G02 compound treatment 0.335 0.0119 0.47 0.327 0.00231 0.05 0.3661 0.7759 1188495 IFLab1_004358 COc1ccc2oc(=O)c(cc2c1)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G03 compound treatment 0.318 -0.00506 -0.2 0.317 -0.00769 -0.16 -0.2545 -0.9944 1336676 IFLab1_004359 CC(C)(NC(=O)C1Cc2ccccc2CN1S(=O)(=O)c3ccc(F)cc3)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G04 compound treatment 0.317 -0.00606 -0.24 0.324 -6.88E-4 -0.01 -0.1787 -0.7484 1214090 IFLab1_004360 CCc1ccc(NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G05 compound treatment 0.317 -0.00606 -0.24 0.316 -0.00869 -0.18 -0.2971 -0.9911 1718943 IFLab1_004361 CCCCn1c(=O)c(C(=O)NC(C)c2ccccc2)c(O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G06 compound treatment 0.325 0.00194 0.08 0.323 -0.00169 -0.04 0.0289 0.3441 1471839 IFLab1_004362 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCc4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G07 compound treatment 0.36 0.0369 1.45 0.352 0.0273 0.57 1.4311 0.9169 2067888 IFLab1_004363 CCN1C(=O)/C(=C\c2cc(C)n(c2C)c3ccccc3)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G08 compound treatment 0.341 0.0179 0.71 0.336 0.0113 0.24 0.6661 0.8954 2067889 IFLab1_004364 Fc1ccccc1CSCCC(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G09 compound treatment 0.328 0.00494 0.19 0.334 0.00931 0.19 0.2751 1.0 1246979 IFLab1_004365 C(Sc1nc2ccccc2o1)c3cn4ccsc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G10 compound treatment 0.337 0.0139 0.55 0.363 0.0383 0.8 0.9544 0.9828 1569276 IFLab1_004366 CCOc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G11 compound treatment 0.333 0.00994 0.39 0.336 0.0113 0.24 0.4437 0.9712 2067890 IFLab1_004367 CC(=O)Nc1ccc(OCC(O)CN2C(C)(C)CC(O)CC2(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G12 compound treatment 0.339 0.0159 0.63 0.345 0.0203 0.43 0.7437 0.9821 1123327 IFLab1_004368 CCC(C)NC(=O)c1ccc2n(cnc2c1)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G13 compound treatment 0.326 0.00294 0.12 0.319 -0.00569 -0.12 -0.0025 -0.015 2067891 IFLab1_004369 Clc1cc(NC(=O)c2ccc(Br)o2)ccc1N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G14 compound treatment 0.345 0.0219 0.86 0.338 0.0133 0.28 0.8069 0.8902 1520717 IFLab1_004370 O=C(Nc1ncccn1)C2c3ccccc3Oc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G15 compound treatment 0.334 0.0109 0.43 0.346 0.0213 0.45 0.6194 0.9998 1488402 IFLab1_004371 On1c(=O)c(=O)n(OCc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G16 compound treatment 0.334 0.0109 0.43 0.321 -0.00369 -0.08 0.2495 0.5711 1299945 IFLab1_004372 CC(O)c1nc2ccccc2n1Cc3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G17 compound treatment 0.372 0.0489 1.92 0.355 0.0303 0.63 1.8091 0.8929 1169121 IFLab1_004373 CCOC(=O)c1c(oc2ccc(OCC(=O)N)cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G18 compound treatment 0.332 0.00894 0.35 0.337 0.0123 0.26 0.4307 0.9884 1361535 IFLab1_004374 CSc1nc(cn1c2ccc(NC(=O)C)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G19 compound treatment 0.328 0.00494 0.19 0.33 0.00531 0.11 0.2159 0.965 1490777 IFLab1_004375 Cc1ccc(cc1Cl)n2c(SCC(=O)c3ccccc3)nc4[nH]ncc4c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G20 compound treatment 0.33 0.00694 0.27 0.34 0.0153 0.32 0.4195 0.9968 2067892 IFLab1_004376 O/N=C\1/CCCc2oc(cc12)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G21 compound treatment 0.336 0.0129 0.51 0.34 0.0153 0.32 0.5863 0.9752 1501794 IFLab1_004377 COc1ccccc1N2CCN(CCC(=O)Nc3ccc4CCCc4c3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G22 compound treatment 0.321 -0.00206 -0.08 0.344 0.0193 0.4 0.2284 0.5542 1914379 IFLab1_004378 CCSc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G23 mock treatment 0.318 -0.00506 -0.2 0.32 -0.00469 -0.1 -0.2101 -0.9468 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 G24 positive control 0.081 -0.242 -9.52 0.082 -0.243 -5.08 -10.3209 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H01 compound treatment 0.38 0.0569 2.24 0.359 0.0343 0.72 2.0907 0.8893 2067893 IFLab1_004379 COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H02 compound treatment 0.335 0.0119 0.47 0.339 0.0143 0.3 0.5437 0.9765 1601208 IFLab1_004380 CCN(CC)CC(O)Cn1c(cc2ccccc12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H03 compound treatment 0.332 0.00894 0.35 0.332 0.00731 0.15 0.3567 0.9306 1693007 IFLab1_004381 CCc1cc(nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H04 compound treatment 0.338 0.0149 0.59 0.346 0.0213 0.45 0.7307 0.9908 1684917 IFLab1_004382 Cc1ccc(OCC(O)Cn2cnc3ccccc23)c(CC=C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H05 compound treatment 0.318 -0.00506 -0.2 0.331 0.00631 0.13 -0.0473 -0.1982 1361158 IFLab1_004383 O=C(CSC1CCCCC1)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H06 compound treatment 0.33 0.00694 0.27 0.335 0.0103 0.22 0.3455 0.9933 1142337 IFLab1_004384 CCC(CO)NCC(O)Cn1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H07 compound treatment 0.349 0.0259 1.02 0.358 0.0333 0.7 1.214 0.9828 1686398 IFLab1_004385 O=C(CSCc1ccccc1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H08 compound treatment 0.354 0.0309 1.22 0.357 0.0323 0.68 1.3383 0.9616 2067894 IFLab1_004386 CN(C)C(=O)Oc1ccc2cc(Br)ccc2c1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H09 compound treatment 0.346 0.0229 0.9 0.346 0.0213 0.45 0.9531 0.9473 1519008 IFLab1_004387 CCOC(=O)c1ccc(NC(=O)CSc2ccc(Cl)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H10 compound treatment 0.363 0.0399 1.57 0.371 0.0463 0.97 1.7956 0.9731 2067895 IFLab1_004388 Cc1sc2nc(SCc3cc(O)[nH]n3)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H11 compound treatment 0.334 0.0109 0.43 0.335 0.0103 0.22 0.4567 0.9491 1503811 IFLab1_004389 Cc1nnc(NC(=O)CSC2CCCCC2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H12 compound treatment 0.263 -0.0601 -2.36 0.272 -0.0527 -1.1 -2.4495 -0.9399 1361283 IFLab1_004390 CN1CCN(CC1)C(c2ccccn2)c3cc(Cl)c4cccnc4c3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H13 compound treatment 0.356 0.0329 1.3 0.338 0.0133 0.28 1.1127 0.84 2067896 IFLab1_004391 COc1cccc(/C=N/c2sc3CCCCc3c2C#N)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H14 compound treatment 0.337 0.0139 0.55 0.336 0.0113 0.24 0.5549 0.9295 1472459 IFLab1_004392 CC(C)NCC(O)COc1ccc2CCCc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H15 compound treatment 0.315 -0.00806 -0.32 0.306 -0.0187 -0.39 -0.5007 -0.9946 1279406 IFLab1_004393 NC(=O)c1cc2ccccc2oc1=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H16 compound treatment 0.34 0.0169 0.67 0.342 0.0173 0.36 0.7271 0.9591 1033666 IFLab1_004394 CN(C)c1ccc(cc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H17 compound treatment 0.347 0.0239 0.94 0.332 0.00731 0.15 0.7737 0.8114 2067897 IFLab1_004395 CCN(CC)c1ccc(/C=N/CCN2CCOCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H18 compound treatment 0.34 0.0169 0.67 0.337 0.0123 0.26 0.6531 0.9146 1740945 IFLab1_004396 Cc1cc(C)nc(SC2CCCCC2NS(=O)(=O)c3ccccc3)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H19 compound treatment 0.339 0.0159 0.63 0.326 0.00131 0.03 0.4625 0.7374 1535475 IFLab1_004397 CC1CN(CCN1C(=O)c2ccc(C)c(C)c2)C(=O)c3ccc(C)c(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H20 compound treatment 0.335 0.0119 0.47 0.339 0.0143 0.3 0.5437 0.9765 1466174 IFLab1_004398 CNC1CCS(=O)(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H21 compound treatment 0.335 0.0119 0.47 0.341 0.0163 0.34 0.5733 0.9878 1472099 IFLab1_004399 Cc1ccc2cccc(OC(=O)c3ccccc3F)c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H22 compound treatment 0.335 0.0119 0.47 0.339 0.0143 0.3 0.5437 0.9765 2067898 IFLab1_004400 CCc1cc2c(SCC(=O)c3ccc(Cl)s3)ncnc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H23 mock treatment 0.322 -0.00106 -0.04 0.323 -0.00169 -0.04 -0.0545 -0.9965 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 H24 positive control 0.082 -0.241 -9.48 0.083 -0.242 -5.06 -10.2783 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I01 compound treatment 0.337 0.0139 0.55 0.353 0.0283 0.59 0.8064 0.9992 2067899 IFLab1_004401 Fc1ccc(cc1)S(=O)(=O)NCc2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I02 compound treatment 0.333 0.00994 0.39 0.336 0.0113 0.24 0.4437 0.9712 1173402 IFLab1_004402 NS(=O)(=O)c1ccccc1N2C(=O)CCC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I03 compound treatment 0.352 0.0289 1.14 0.347 0.0223 0.47 1.1347 0.9226 1318426 IFLab1_004403 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)Nc4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I04 compound treatment 0.386 0.0629 2.47 0.362 0.0373 0.78 2.3019 0.8871 1258637 IFLab1_004404 OC(=O)c1ccc2NC(CSCc3ccccc3Cl)C(=O)Nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I05 compound treatment 0.344 0.0209 0.82 0.347 0.0223 0.47 0.9123 0.9639 1002849 IFLab1_004405 c1ccc(cc1)c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I06 compound treatment 0.356 0.0329 1.3 0.358 0.0333 0.7 1.4087 0.9578 1696315 IFLab1_004406 Cc1ccc(cc1Cl)n2cnc3cc(ccc23)C(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I07 compound treatment 0.344 0.0209 0.82 0.353 0.0283 0.59 1.001 0.987 2067900 IFLab1_004407 OC(=O)c1ccc(s1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I08 compound treatment 0.349 0.0259 1.02 0.349 0.0243 0.51 1.0809 0.9484 2067901 IFLab1_004408 COc1ccc(CNC(=O)CCSCc2ccccc2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I09 compound treatment 0.331 0.00794 0.31 0.341 0.0163 0.34 0.4621 0.999 2067902 IFLab1_004409 O=S(=O)(Cc1ccccc1)n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I10 compound treatment 0.349 0.0259 1.02 0.35 0.0253 0.53 1.0957 0.9534 1659314 IFLab1_004410 COc1ccccc1CNC(=O)c2sc3nc[nH]c(=O)c3c2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I11 compound treatment 0.353 0.0299 1.18 0.354 0.0293 0.61 1.2661 0.9538 1661541 IFLab1_004411 CC1(C)CC(O)CC(C)(C)N1CC(O)COc2ccc(cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I12 compound treatment 0.336 0.0129 0.51 0.344 0.0193 0.4 0.6455 0.9935 1286186 IFLab1_004412 Cc1nc2cc(ccc2n1c3ccc(F)cc3F)C(=O)NCCN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I13 compound treatment 0.347 0.0239 0.94 0.339 0.0143 0.3 0.8773 0.8882 1223709 IFLab1_004413 COc1cccc(c1)C(=O)N2CCN(Cc3cccc4ccccc34)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I14 compound treatment 0.352 0.0289 1.14 0.352 0.0273 0.57 1.2087 0.9493 1647689 IFLab1_004414 O=C(Nc1nc[nH]n1)C2c3ccccc3Oc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I15 compound treatment 0.337 0.0139 0.55 0.339 0.0143 0.3 0.5993 0.9596 1685824 IFLab1_004415 CCOC(=O)c1oc2cccc(O)c2c1CN(Cc3ccccc3)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I16 compound treatment 0.335 0.0119 0.47 0.322 -0.00269 -0.06 0.2921 0.618 2067903 IFLab1_004416 Cc1ccc(Cn2cnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I17 compound treatment 0.337 0.0139 0.55 0.35 0.0253 0.53 0.762 0.9999 1676733 IFLab1_004417 CC(=O)N1CCN(CC1)c2ccc(NC(=O)c3cc(Br)ccc3Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I18 compound treatment 0.337 0.0139 0.55 0.342 0.0173 0.36 0.6437 0.9798 1219407 IFLab1_004418 OC(=O)c1c(Nc2nnc(s2)c3ccncc3)sc4CCCCc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I19 compound treatment 0.351 0.0279 1.1 0.363 0.0383 0.8 1.3436 0.988 1392974 IFLab1_004419 O=C1CCCc2c1[nH]c3ccc(cc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I20 compound treatment 0.339 0.0159 0.63 0.306 -0.0187 -0.39 0.1666 0.2255 1523614 IFLab1_004420 CC(=O)n1cc(c2c(O)c3ccccc3oc2=O)c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I21 compound treatment 0.33 0.00694 0.27 0.34 0.0153 0.32 0.4195 0.9968 1498479 IFLab1_004421 CCOC(=O)C1CCCN(CCC(=O)Nc2cc(C)ccc2C)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I22 compound treatment 0.329 0.00594 0.23 0.34 0.0153 0.32 0.3917 0.9879 1865662 IFLab1_004422 CCOC(=O)N1CCN(CC1)S(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I23 mock treatment 0.325 0.00194 0.08 0.324 -6.88E-4 -0.01 0.0437 0.5636 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 I24 positive control 0.083 -0.24 -9.44 0.088 -0.237 -4.95 -10.1765 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J01 compound treatment 0.329 0.00594 0.23 0.329 0.00431 0.09 0.2289 0.9145 2067904 IFLab1_004423 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J02 compound treatment 0.364 0.0409 1.61 0.364 0.0393 0.82 1.7199 0.9514 1539414 IFLab1_004424 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CN4CCCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J03 compound treatment 0.34 0.0169 0.67 0.356 0.0313 0.66 0.9342 1.0 2067905 IFLab1_004425 CCOC(=O)c1csc(NC(=O)/C=C/c2cccs2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J04 compound treatment 0.359 0.0359 1.41 0.363 0.0383 0.8 1.566 0.964 1510071 IFLab1_004426 Cc1ccc(OCC(O)Cn2c(CO)nc3ccccc23)c(CC=C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J05 compound treatment 0.309 -0.0141 -0.55 0.323 -0.00169 -0.04 -0.4159 -0.7507 1152963 IFLab1_004427 O=C(CSC1CCCCC1)N2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J06 compound treatment 0.38 0.0569 2.24 0.367 0.0423 0.89 2.2091 0.9176 1153478 IFLab1_004428 CC(=O)Nc1ccc(NC2SC(=O)N(C2=O)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J07 compound treatment 0.315 -0.00806 -0.32 0.333 0.00831 0.17 -0.1012 -0.2797 1705520 IFLab1_004429 O=C(CSC1=NCCS1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J08 compound treatment 0.331 0.00794 0.31 0.335 0.0103 0.22 0.3733 0.9838 1179186 IFLab1_004430 C(N1CCN(CC1)c2ncccn2)c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J09 compound treatment 0.454 0.131 5.15 0.455 0.13 2.73 5.5686 0.9558 1167109 IFLab1_004431 Cc1ccc(NC(=O)CSC2=NCCS2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J10 compound treatment 0.362 0.0389 1.53 0.359 0.0343 0.72 1.5903 0.9404 1287571 IFLab1_004432 O=C1OCCC1Sc2nc3sc4CCCCc4c3c(=O)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J11 compound treatment 0.343 0.0199 0.78 0.342 0.0173 0.36 0.8105 0.9385 1181391 IFLab1_004433 Cc1cc(NC(=O)CSCc2ccccc2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J12 compound treatment 0.342 0.0189 0.74 0.346 0.0213 0.45 0.8419 0.97 1684818 IFLab1_004434 OCc1cc(=O)c(O)c(CN2CCN(CC2)c3ccccc3F)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J13 compound treatment 0.344 0.0209 0.82 0.35 0.0253 0.53 0.9567 0.9773 2067906 IFLab1_004435 CCN(CC)c1ccc(O)c(/C=N/c2ccc(cc2)S(=O)(=O)N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J14 compound treatment 0.337 0.0139 0.55 0.321 -0.00369 -0.08 0.3329 0.6016 1702055 IFLab1_004436 CCOC(=O)N1CCN(CC(O)COc2ccc3CCCc3c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J15 compound treatment 0.344 0.0209 0.82 0.345 0.0203 0.43 0.8827 0.9527 1138056 IFLab1_004437 COc1ccc(N=c2oc3ccccc3cc2C(=O)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J16 compound treatment 0.34 0.0169 0.67 0.334 0.00931 0.19 0.6087 0.8772 1508530 IFLab1_004438 Cc1csc(n1)c2c[nH]nc2c3c(O)cc(C)cc3O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J17 compound treatment 0.331 0.00794 0.31 0.333 0.00831 0.17 0.3437 0.9619 1032629 IFLab1_004439 COc1ccccc1NS(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J18 compound treatment 0.343 0.0199 0.78 0.343 0.0183 0.38 0.8253 0.9458 2067907 IFLab1_004440 COC1CCCCC1NS(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J19 compound treatment 0.33 0.00694 0.27 0.345 0.0203 0.43 0.4934 0.977 1616918 IFLab1_004441 Cc1ccc2cccc(OC(=O)c3ccc(C)c(C)c3)c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J20 compound treatment 0.342 0.0189 0.74 0.345 0.0203 0.43 0.8271 0.9647 1370608 IFLab1_004442 CN1CCN(CC1)C(=O)c2ccc(o2)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J21 compound treatment 0.341 0.0179 0.71 0.344 0.0193 0.4 0.7845 0.9651 2067908 IFLab1_004443 CN(C)C(=S)SCN1CCCC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J22 compound treatment 0.341 0.0179 0.71 0.343 0.0183 0.38 0.7697 0.9589 2067909 IFLab1_004444 Cc1sc2ncnc(SCC(=O)c3ccc(C)cc3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J23 mock treatment 0.322 -0.00106 -0.04 0.323 -0.00169 -0.04 -0.0545 -0.9965 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 J24 positive control 0.084 -0.239 -9.4 0.084 -0.241 -5.04 -10.2079 -0.9572 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K01 compound treatment 0.343 0.0199 0.78 0.351 0.0263 0.55 0.9437 0.9851 1277021 IFLab1_004445 CC(=C)CSc1nnc2c3ccccc3[nH]c2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K02 compound treatment 0.323 -6.25E-5 0.0 0.328 0.00331 0.07 0.0473 0.6816 2067910 IFLab1_004446 FC(F)(F)c1cccc(NC(=O)CSc2ncccc2C(=O)NCc3cccnc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K03 compound treatment 0.351 0.0279 1.1 0.343 0.0183 0.38 1.0477 0.9006 2067911 IFLab1_004447 CS(=O)(=O)/N=C(\NC#N)/c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K04 compound treatment 0.323 -6.25E-5 0.0 0.328 0.00331 0.07 0.0473 0.6816 1409951 IFLab1_004448 CCCNC(=O)c1ccc2n(cnc2c1)c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K05 compound treatment 0.32 -0.00306 -0.12 0.319 -0.00569 -0.12 -0.1693 -1.0 1371388 IFLab1_004449 CCN(CC)Cc1c[nH]c2c(cccc12)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K06 compound treatment 0.337 0.0139 0.55 0.331 0.00631 0.13 0.4809 0.8531 1710118 IFLab1_004450 CCC(C)NC(=O)c1ccc2n(cnc2c1)c3cc(C)cc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K07 compound treatment 0.322 -0.00106 -0.04 0.332 0.00731 0.15 0.0787 0.4959 2067912 IFLab1_004451 Brc1ccc(cc1)c2nnc3SC(=C)Cn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K08 compound treatment 0.34 0.0169 0.67 0.345 0.0203 0.43 0.7715 0.9765 1154278 IFLab1_004452 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)Nc4cccc(Cl)c4C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K09 compound treatment 0.341 0.0179 0.71 0.346 0.0213 0.45 0.8141 0.9756 2067913 IFLab1_004453 CC(C)Oc1ccc(cc1N)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K10 compound treatment 0.365 0.0419 1.65 0.37 0.0453 0.95 1.8364 0.9655 1302617 IFLab1_004454 Cc1c(sc2nc[nH]c(=O)c12)C(=O)N3CCN(CC3)c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K11 compound treatment 0.335 0.0119 0.47 0.345 0.0203 0.43 0.6325 0.9988 2067914 IFLab1_004455 C=CCSc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K12 compound treatment 0.347 0.0239 0.94 0.35 0.0253 0.53 1.0401 0.963 1198483 IFLab1_004456 Cc1nc2cc(ccc2n1c3cccc(F)c3)C(=O)NCc4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K13 compound treatment 0.344 0.0209 0.82 0.347 0.0223 0.47 0.9123 0.9639 1328673 IFLab1_004457 COc1ccc(CN2CCN(CC2)C(=O)c3ccccc3F)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K14 compound treatment 0.343 0.0199 0.78 0.346 0.0213 0.45 0.8697 0.9643 2067915 IFLab1_004458 Cc1cc(O)nc(SCc2cn3ccccc3n2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K15 compound treatment 0.336 0.0129 0.51 0.363 0.0383 0.8 0.9266 0.9759 1293452 IFLab1_004459 Clc1ccc(CC(=O)Nc2cccc3nsnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K16 compound treatment 0.337 0.0139 0.55 0.333 0.00831 0.17 0.5105 0.8879 1651872 IFLab1_004460 CCOCN(C(=O)Cn1cnc2ccccc12)c3c(C)cccc3CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K17 compound treatment 0.34 0.0169 0.67 0.347 0.0223 0.47 0.8011 0.9849 1653161 IFLab1_004461 Cc1cccc(NC(=O)CCS(=O)(=O)c2ccccc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K18 compound treatment 0.346 0.0229 0.9 0.341 0.0163 0.34 0.8791 0.9116 1510088 IFLab1_004462 CC(C)N(C(=O)CSc1nc2ccccc2n1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K19 compound treatment 0.351 0.0279 1.1 0.355 0.0303 0.63 1.2253 0.966 1404903 IFLab1_004463 COc1ccc(Oc2ccc3[nH]c4C(=O)CCCc4c3c2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K20 compound treatment 0.365 0.0419 1.65 0.369 0.0443 0.93 1.8216 0.9629 2067916 IFLab1_004464 O=C(/C=C/1\C(=O)Nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K21 compound treatment 0.332 0.00894 0.35 0.341 0.0163 0.34 0.4899 0.9999 1607380 IFLab1_004465 COc1cc2CN(C(=O)c3ccccc3)C(C)(C)Cc2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K22 compound treatment 0.338 0.0149 0.59 0.343 0.0183 0.38 0.6863 0.9786 1643121 IFLab1_004466 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K23 mock treatment 0.324 9.38E-4 0.04 0.321 -0.00369 -0.08 -0.0285 -0.3333 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 K24 positive control 0.085 -0.238 -9.36 0.086 -0.239 -4.99 -10.1505 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L01 compound treatment 0.344 0.0209 0.82 0.346 0.0213 0.45 0.8975 0.9586 2067917 IFLab1_004467 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L02 compound treatment 0.352 0.0289 1.14 0.347 0.0223 0.47 1.1347 0.9226 1318328 IFLab1_004468 Cc1c(C)c2ccccc2n1CC(O)CNc3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L03 compound treatment 0.323 -6.25E-5 0.0 0.324 -6.88E-4 -0.01 -0.0119 -0.8161 2067918 IFLab1_004469 Clc1ccc(SCC(=O)N2CCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L04 compound treatment 0.315 -0.00806 -0.32 0.316 -0.00869 -0.18 -0.3527 -0.9652 1416271 IFLab1_004470 Cc1ccc(OCC(O)CN2CCN(CC2)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L05 compound treatment 0.317 -0.00606 -0.24 0.315 -0.00969 -0.2 -0.3119 -0.9968 1361906 IFLab1_004471 O=C(CSC1CCCCC1)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L06 compound treatment 0.385 0.0619 2.44 0.382 0.0573 1.2 2.57 0.9468 1475405 IFLab1_004472 Cc1ccc(NC2SC(=O)N(C2=O)c3ccc(C)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L07 compound treatment 0.331 0.00794 0.31 0.325 3.12E-4 0.01 0.2253 0.7218 1236624 IFLab1_004473 O=C(CSc1nc2ccccc2s1)N3CCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L08 compound treatment 0.321 -0.00206 -0.08 0.334 0.00931 0.19 0.0805 0.3812 2067919 IFLab1_004474 NC1(Oc2cc(Cl)c(Cl)cc2O1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L09 compound treatment 0.318 -0.00506 -0.2 0.337 0.0123 0.26 0.0414 0.1273 2067920 IFLab1_004475 FC(F)(F)c1ccc(Cl)c(NC(=O)CSCc2ccco2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L10 compound treatment 0.34 0.0169 0.67 0.345 0.0203 0.43 0.7715 0.9765 1536276 IFLab1_004476 Cc1ccc(NC(c2ccc(O)cc2)P(=O)(c3ccccc3)c4ccccc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L11 compound treatment 0.374 0.0509 2.0 0.377 0.0523 1.09 2.1902 0.9596 1742239 IFLab1_004477 Cc1cc(NC(=O)CSC2=NCCS2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L12 compound treatment 0.337 0.0139 0.55 0.346 0.0213 0.45 0.7029 0.9948 1458992 IFLab1_004478 S=C(SCc1cn2ccccc2n1)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L13 compound treatment 0.343 0.0199 0.78 0.353 0.0283 0.59 0.9732 0.9905 2067921 IFLab1_004479 Oc1c(CC=C)cccc1/C=N/c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L14 compound treatment 0.335 0.0119 0.47 0.343 0.0183 0.38 0.6029 0.9949 1503358 IFLab1_004480 CC(NCC(O)COc1ccc2CCCc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L15 compound treatment 0.364 0.0409 1.61 0.356 0.0313 0.66 1.6015 0.9215 1382037 IFLab1_004481 NC(=O)c1cc2ccccc2oc1=NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L16 compound treatment 0.336 0.0129 0.51 0.323 -0.00169 -0.04 0.3347 0.6564 2067922 IFLab1_004482 Cc1nc(cs1)c2c(noc2c3ccc(O)cc3O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L17 compound treatment 0.336 0.0129 0.51 0.353 0.0283 0.59 0.7786 0.9971 2067923 IFLab1_004483 Oc1ccc(cc1)C(=O)OCC(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L18 compound treatment 0.332 0.00894 0.35 0.332 0.00731 0.15 0.3567 0.9306 1610504 IFLab1_004484 CS(=O)(=O)Nc1cc(Br)c(O)c(Br)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L19 compound treatment 0.342 0.0189 0.74 0.35 0.0253 0.53 0.9011 0.9861 1180167 IFLab1_004485 Cc1ccc(cc1C)C(=O)NCc2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L20 compound treatment 0.176 -0.147 -5.78 0.188 -0.137 -2.86 -6.1112 -0.9473 1407742 IFLab1_004486 O=C1CCCCCN1Sc2c(nc3sccn23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L21 compound treatment 0.342 0.0189 0.74 0.329 0.00431 0.09 0.5903 0.787 1016009 IFLab1_004487 O=C1CCCCC1CN2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L22 compound treatment 0.338 0.0149 0.59 0.353 0.0283 0.59 0.8342 1.0 1135361 IFLab1_004488 COc1ccc(CCNS(=O)(=O)c2cccc3cccnc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L23 mock treatment 0.326 0.00294 0.12 0.328 0.00331 0.07 0.1307 0.9702 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 L24 positive control 0.085 -0.238 -9.36 0.091 -0.234 -4.89 -10.0765 -0.9542 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M01 compound treatment 0.333 0.00994 0.39 0.333 0.00831 0.17 0.3993 0.9336 1513352 IFLab1_004489 COc1ccc(cc1OC)C(=O)N2CCc3cc(OC)c(OC)cc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M02 compound treatment 0.334 0.0109 0.43 0.337 0.0123 0.26 0.4863 0.97 1171272 IFLab1_004490 Fc1ccc(cc1C(=O)Nc2cccc(Cl)c2)S(=O)(=O)N3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M03 compound treatment 0.291 -0.0321 -1.26 0.293 -0.0317 -0.66 -1.3603 -0.955 2067924 IFLab1_004491 CS(=O)(=O)/N=C(\N)/c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M04 compound treatment 0.321 -0.00206 -0.08 0.325 3.12E-4 0.01 -0.0527 -0.648 2067925 IFLab1_004492 OC(=O)c1ccc(CSCc2c(F)cccc2Cl)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M05 compound treatment 0.305 -0.0181 -0.71 0.326 0.00131 0.03 -0.4828 -0.6793 2067926 IFLab1_004493 NC(=O)c1ccccc1NC(=O)CSc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M06 compound treatment 0.331 0.00794 0.31 0.334 0.00931 0.19 0.3585 0.9743 1645794 IFLab1_004494 Cc1ccc(NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M07 compound treatment 0.329 0.00594 0.23 0.322 -0.00269 -0.06 0.1253 0.5218 1223484 IFLab1_004495 CC(=O)Nc1ccc2nc(N)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M08 compound treatment 0.338 0.0149 0.59 0.343 0.0183 0.38 0.6863 0.9786 1452318 IFLab1_004496 OC(=O)CC(NS(=O)(=O)c1ccc(Cl)cc1)c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M09 compound treatment 0.358 0.0349 1.37 0.351 0.0263 0.55 1.3607 0.9194 2067927 IFLab1_004497 C(Sc1nnnn1c2ccccc2)c3csc(n3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M10 compound treatment 0.344 0.0209 0.82 0.354 0.0293 0.61 1.0158 0.9895 2067928 IFLab1_004498 Cc1c(sc2nc[nH]c(=O)c12)C(=O)Nc3nc4ccc(Br)cc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M11 compound treatment 0.353 0.0299 1.18 0.358 0.0333 0.7 1.3253 0.9687 1006147 IFLab1_004499 CSc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M12 compound treatment 0.354 0.0309 1.22 0.373 0.0483 1.01 1.575 0.9958 1652255 IFLab1_004500 Cc1cc(C)cc(Nc2ccc(cc2N)C(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M13 compound treatment 0.327 0.00394 0.15 0.347 0.0223 0.47 0.4396 0.8937 1484553 IFLab1_004501 COc1cc(CN2CCN(Cc3ccc4ccccc4c3)CC2)cc(OC)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M14 compound treatment 0.345 0.0219 0.86 0.349 0.0243 0.51 0.9697 0.9683 2067929 IFLab1_004502 Cc1cc(O)nc(SCc2nc3ccccn3c2Br)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M15 compound treatment 0.343 0.0199 0.78 0.349 0.0243 0.51 0.9141 0.9781 1315868 IFLab1_004503 O=C(N1CCCCCC1)c2cccc(c2)N3C(=O)C4CC=CCC4C3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M16 compound treatment 0.325 0.00194 0.08 0.324 -6.88E-4 -0.01 0.0437 0.5636 1328703 IFLab1_004504 CC(=O)Nc1ccc(NC(=O)Oc2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M17 compound treatment 0.344 0.0209 0.82 0.341 0.0163 0.34 0.8235 0.924 2067930 IFLab1_004505 CCOc1ccc(cc1)c2ncnn2c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M18 compound treatment 0.348 0.0249 0.98 0.339 0.0143 0.3 0.9051 0.8828 1126378 IFLab1_004506 COc1ccccc1Nc2nc(cs2)c3ccc(OC)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M19 compound treatment 0.303 -0.0201 -0.79 0.318 -0.00669 -0.14 -0.6567 -0.8198 1729956 IFLab1_004507 CC12C3CC(C=C3)C2C(=O)N(Cc4ccccc4)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M20 compound treatment 0.367 0.0439 1.73 0.35 0.0253 0.53 1.5961 0.8833 1257229 IFLab1_004508 COc1cc2cc(O)nc(C)c2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M21 compound treatment 0.348 0.0249 0.98 0.345 0.0203 0.43 0.9939 0.93 1365211 IFLab1_004509 CCOC(=O)C1CCCc2c1[nH]c3c(cccc23)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M22 compound treatment 0.343 0.0199 0.78 0.318 -0.00669 -0.14 0.4553 0.5718 2067931 IFLab1_004510 O=C(/C=C\c1cccs1)N2CCN(Cc3ccc4OCOc4c3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M23 mock treatment 0.326 0.00294 0.12 0.33 0.00531 0.11 0.1603 0.9998 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 M24 positive control 0.087 -0.236 -9.28 0.088 -0.237 -4.95 -10.0653 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N01 compound treatment 0.335 0.0119 0.47 0.334 0.00931 0.19 0.4697 0.9242 1865661 IFLab1_004511 COC(=O)c1ccc(NS(=O)(=O)/C=C/c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N02 compound treatment 0.318 -0.00506 -0.2 0.317 -0.00769 -0.16 -0.2545 -0.9944 1436371 IFLab1_004512 OC(COc1ccc(Br)cc1)Cn2nnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N03 compound treatment 0.318 -0.00506 -0.2 0.32 -0.00469 -0.1 -0.2101 -0.9468 1486361 IFLab1_004513 O=C(CSc1nc2ccccc2s1)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N04 compound treatment 0.33 0.00694 0.27 0.339 0.0143 0.3 0.4047 0.9989 1327244 IFLab1_004514 Cc1nc2ccccc2n1CC(O)COc3ccccc3CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N05 compound treatment 0.315 -0.00806 -0.32 0.331 0.00631 0.13 -0.1307 -0.3807 1271955 IFLab1_004515 O=C(CSCc1ccccc1)N2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N06 compound treatment 0.32 -0.00306 -0.12 0.33 0.00531 0.11 -0.0065 -0.0399 1406581 IFLab1_004516 Clc1cc(Br)c(OC(=O)N2CCOCC2)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N07 compound treatment 0.334 0.0109 0.43 0.328 0.00331 0.07 0.3531 0.8106 2067932 IFLab1_004517 Clc1ccc(SCC(=O)N2CCCc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N08 compound treatment 0.335 0.0119 0.47 0.341 0.0163 0.34 0.5733 0.9878 1607731 IFLab1_004518 Fc1ccc(cc1)C(=O)Nc2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N09 compound treatment 0.467 0.144 5.66 0.442 0.117 2.45 5.7376 0.9301 2067933 IFLab1_004519 FC(F)(F)c1ccc(Cl)c(NC(=O)CSC2=NCCS2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N10 compound treatment 0.34 0.0169 0.67 0.344 0.0193 0.4 0.7567 0.9714 3061579 IFLab1_004520 Cc1sc2sc(c(N)[n+]2c1C)c3ccccc3.OS(=O)(=O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N11 compound treatment 0.398 0.0749 2.95 0.388 0.0633 1.32 3.0203 0.9349 1410761 IFLab1_004521 Cc1cc(NC(=O)CSc2nc3ccccc3s2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N12 compound treatment 0.402 0.0789 3.1 0.376 0.0513 1.07 2.9539 0.8994 1690107 IFLab1_004522 Cc1cc(NC(c2cccc(Br)c2)c3ccc4cccnc4c3O)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N13 compound treatment 0.343 0.0199 0.78 0.349 0.0243 0.51 0.9141 0.9781 2067935 IFLab1_004523 c1ccc(cc1)c2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N14 compound treatment 0.333 0.00994 0.39 0.337 0.0123 0.26 0.4585 0.9796 1582367 IFLab1_004524 CCN(CC(O)COc1ccc(Cl)cc1Cl)Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N15 compound treatment 0.343 0.0199 0.78 0.331 0.00631 0.13 0.6477 0.8148 1499530 IFLab1_004525 Clc1cc(Cl)c2oc(=O)c(cc2c1)C(=O)NCCC3=CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N16 compound treatment 0.343 0.0199 0.78 0.343 0.0183 0.38 0.8253 0.9458 1019542 IFLab1_004526 c1nc(oc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N17 compound treatment 0.338 0.0149 0.59 0.339 0.0143 0.3 0.6271 0.9512 2067936 IFLab1_004527 Oc1ccccc1C(=O)OCC(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N18 compound treatment 0.353 0.0299 1.18 0.349 0.0243 0.51 1.1921 0.9296 1298704 IFLab1_004528 Cc1ccc(cc1)S(=O)(=O)Nc2cc(C)c3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N19 compound treatment 0.344 0.0209 0.82 0.347 0.0223 0.47 0.9123 0.9639 1376525 IFLab1_004529 COc1ccc(Br)cc1S(=O)(=O)NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N20 compound treatment 0.342 0.0189 0.74 0.345 0.0203 0.43 0.8271 0.9647 2067937 IFLab1_004530 COC(=O)CCNc1ccccn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N21 compound treatment 0.342 0.0189 0.74 0.345 0.0203 0.43 0.8271 0.9647 2067938 IFLab1_004531 OCN1CCCCCC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N22 compound treatment 0.346 0.0229 0.9 0.343 0.0183 0.38 0.9087 0.9273 1247227 IFLab1_004532 O=C(N1CCc2ccccc12)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N23 mock treatment 0.327 0.00394 0.15 0.327 0.00231 0.05 0.1437 0.8859 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 N24 positive control 0.088 -0.235 -9.24 0.089 -0.236 -4.93 -10.0227 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O01 compound treatment 0.328 0.00494 0.19 0.324 -6.88E-4 -0.01 0.1271 0.6529 1385689 IFLab1_004533 COc1ccc(cc1OC)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O02 compound treatment 0.365 0.0419 1.65 0.364 0.0393 0.82 1.7477 0.9484 2067939 IFLab1_004534 Cc1[nH]nc2nc(SCc3ccccc3Cl)n(c4ccc(Cl)c(C)c4)c(=N)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O03 compound treatment 0.305 -0.0181 -0.71 0.307 -0.0177 -0.37 -0.7639 -0.9539 2067940 IFLab1_004535 C/C(=N\S(=O)(=O)c1ccc(Cl)cc1)/N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O04 compound treatment 0.323 -6.25E-5 0.0 0.324 -6.88E-4 -0.01 -0.0119 -0.8161 1133737 IFLab1_004536 CCCNC(=O)c1ccc2n(cnc2c1)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O05 compound treatment 0.316 -0.00706 -0.28 0.314 -0.0107 -0.22 -0.3545 -0.9942 1008818 IFLab1_004537 OC(=O)c1ccccc1C(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O06 compound treatment 0.315 -0.00806 -0.32 0.32 -0.00469 -0.1 -0.2935 -0.8845 1193623 IFLab1_004538 Cc1ccc(NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O07 compound treatment 0.323 -6.25E-5 0.0 0.327 0.00231 0.05 0.0325 0.6703 1119595 IFLab1_004539 OC(=O)C1(CC1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O08 compound treatment 0.331 0.00794 0.31 0.337 0.0123 0.26 0.4029 0.9955 1598317 IFLab1_004540 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3F)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O09 compound treatment 0.318 -0.00506 -0.2 0.332 0.00731 0.15 -0.0325 -0.1296 2067941 IFLab1_004541 CC(C)Cc1nc2ccccc2n1C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O10 compound treatment 0.334 0.0109 0.43 0.329 0.00431 0.09 0.3679 0.8373 1631779 IFLab1_004542 COc1ccc(NC(=O)c2oc(=O)c3ccccc3c2c4ccccc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O11 compound treatment 0.325 0.00194 0.08 0.338 0.0133 0.28 0.2509 0.8686 1153827 IFLab1_004543 CCn1c(NN)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O12 compound treatment 0.354 0.0309 1.22 0.359 0.0343 0.72 1.3679 0.9684 2067942 IFLab1_004544 OCCCc1nc2cc(Cc3ccc4[nH]c(CCCO)nc4c3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O13 compound treatment 0.34 0.0169 0.67 0.339 0.0143 0.3 0.6827 0.9349 1178468 IFLab1_004545 COc1cccc(CN2CCN(Cc3cccnc3)CC2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O14 compound treatment 0.331 0.00794 0.31 0.336 0.0113 0.24 0.3881 0.9907 1354178 IFLab1_004546 CC(C)C1CCC(C)CC1OP(=O)(N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O15 compound treatment 0.348 0.0249 0.98 0.344 0.0193 0.4 0.9791 0.9232 2067943 IFLab1_004547 COC(=O)c1cn(nc1N)C(=O)c2cc(Br)ccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O16 compound treatment 0.345 0.0219 0.86 0.329 0.00431 0.09 0.6737 0.7768 2067944 IFLab1_004548 Brc1ccccc1/N=C/c2ccc(OC(=O)c3ccccn3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O17 compound treatment 0.348 0.0249 0.98 0.35 0.0253 0.53 1.0679 0.9582 2067945 IFLab1_004549 COc1ccccc1c2nc(cc(=O)o2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O18 compound treatment 0.339 0.0159 0.63 0.344 0.0193 0.4 0.7289 0.9775 1704237 IFLab1_004550 COc1ccc(C(=O)CSc2nc3ccccc3n2C)c(F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O19 compound treatment 0.339 0.0159 0.63 0.343 0.0183 0.38 0.7141 0.9722 2067946 IFLab1_004551 CCC(C)(O)c1cn(Cc2ccccc2)nn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O20 compound treatment 0.338 0.0149 0.59 0.345 0.0203 0.43 0.7159 0.9874 1026023 IFLab1_004552 CCCSc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O21 compound treatment 0.338 0.0149 0.59 0.345 0.0203 0.43 0.7159 0.9874 1366338 IFLab1_004553 CCOC(=O)c1c(N)c(C#N)c2CCCCCn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O22 compound treatment 0.34 0.0169 0.67 0.343 0.0183 0.38 0.7419 0.9656 2067947 IFLab1_004554 Cc1ccc(cc1)c2nnc(SCC(=O)c3ccc(Cl)cc3)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O23 mock treatment 0.322 -0.00106 -0.04 0.323 -0.00169 -0.04 -0.0545 -0.9965 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 O24 positive control 0.09 -0.233 -9.16 0.091 -0.234 -4.89 -9.9375 -0.9567 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P01 compound treatment 0.332 0.00894 0.35 0.328 0.00331 0.07 0.2975 0.8306 2067948 IFLab1_004555 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P02 compound treatment 0.327 0.00394 0.15 0.325 3.12E-4 0.01 0.1141 0.7363 1671185 IFLab1_004556 Cc1nccn1CC(O)COc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P03 compound treatment 0.326 0.00294 0.12 0.325 3.12E-4 0.01 0.0863 0.7459 1279371 IFLab1_004557 O=C(CSc1nc2ccccc2o1)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P04 compound treatment 0.349 0.0259 1.02 0.348 0.0233 0.49 1.0661 0.943 1129329 IFLab1_004558 Cc1ccc(NCC(O)COc2ccc(OCc3ccccc3)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P05 compound treatment 0.351 0.0279 1.1 0.342 0.0173 0.36 1.0329 0.893 1197141 IFLab1_004559 CCOC(=O)N1CCN(CC1)C(=O)CSc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P06 compound treatment 0.346 0.0229 0.9 0.349 0.0243 0.51 0.9975 0.9633 1151475 IFLab1_004560 CCN(CC)C(=O)Oc1c(I)cc(Cl)c2cccnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P07 compound treatment 0.364 0.0409 1.61 0.36 0.0353 0.74 1.6607 0.9376 2067949 IFLab1_004561 FC(F)(F)c1ccccc1NC(=O)CSc2ncccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P08 compound treatment 0.4 0.0769 3.03 0.372 0.0473 0.99 2.8391 0.892 2067950 IFLab1_004562 FC(F)(F)C(=O)NC1(Oc2ccccc2O1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P09 compound treatment 0.36 0.0369 1.45 0.358 0.0333 0.7 1.5199 0.9435 1724321 IFLab1_004563 O=C(CSC1CCCCC1)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P10 compound treatment 0.432 0.109 4.28 0.404 0.0793 1.66 4.2023 0.9148 3176314 IFLab1_004564 CSc1sc(c2NC(=O)C[n+]12)c3ccccc3.OS(=O)(=O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P11 compound treatment 0.364 0.0409 1.61 0.366 0.0413 0.86 1.7495 0.9575 1620221 IFLab1_004565 CCOC(=O)c1c(NC(=O)C(C)Sc2ncccn2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P12 compound treatment 0.403 0.0799 3.14 0.411 0.0863 1.81 3.4996 0.9654 1616233 IFLab1_004566 CC1(C)CC(CC(C)(C)N1)N2COc3c(C2)cc(Cl)c4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P13 compound treatment 0.391 0.0679 2.67 0.386 0.0613 1.28 2.796 0.9435 1205710 IFLab1_004567 CCOC(=O)c1cc2cc(OC)ccc2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P14 compound treatment 0.352 0.0289 1.14 0.351 0.0263 0.55 1.1939 0.9445 1412296 IFLab1_004568 CC1(C)CC(O)CC(C)(C)N1CC(O)COCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P15 compound treatment 0.354 0.0309 1.22 0.351 0.0263 0.55 1.2495 0.9358 1440750 IFLab1_004569 CCOc1ccccc1NC(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P16 compound treatment 0.346 0.0229 0.9 0.361 0.0363 0.76 1.175 0.9964 1548337 IFLab1_004570 O=S(=O)(NC1CCCCC1N2CCCCC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P17 compound treatment 0.35 0.0269 1.06 0.347 0.0223 0.47 1.0791 0.9323 2067952 IFLab1_004571 Cc1sc2ncnc(O)c2c1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P18 compound treatment 0.357 0.0339 1.33 0.363 0.0383 0.8 1.5104 0.9703 1518118 IFLab1_004572 CC1=C(C(c2ccc(F)cc2)n3ncnc3N1)C(=O)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P19 compound treatment 0.36 0.0369 1.45 0.364 0.0393 0.82 1.6086 0.9638 1289630 IFLab1_004573 COc1ccc(OC)c(c1)S(=O)(=O)NCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P20 compound treatment 0.356 0.0329 1.3 0.358 0.0333 0.7 1.4087 0.9578 2067953 IFLab1_004574 CN(C1CCS(=O)(=O)C1)C(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P21 compound treatment 0.342 0.0189 0.74 0.349 0.0243 0.51 0.8863 0.9828 2067954 IFLab1_004575 CN(C)C(=S)SCN1CCCCCC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P22 compound treatment 0.325 0.00194 0.08 0.351 0.0263 0.55 0.4432 0.7973 1384114 IFLab1_004576 Cc1ccc(cc1)c2nc3SC(CC(=O)n3n2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P23 mock treatment 0.33 0.00694 0.27 0.325 3.12E-4 0.01 0.1975 0.7239 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1424 P24 positive control 0.094 -0.229 -9.01 0.094 -0.231 -4.83 -9.7819 -0.9573 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A01 compound treatment 0.343 0.018 0.71 0.344 0.0147 0.31 0.7178 0.9303 1867102 IFLab1_004577 COc1ccccc1N2CCN(CC2)S(=O)(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A02 compound treatment 0.318 -0.007 -0.28 0.355 0.0257 0.54 0.1855 0.3071 2067955 IFLab1_004578 COc1cc(/C=N/S(=O)(=O)CCc2ccccc2)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A03 compound treatment 0.313 -0.012 -0.47 0.324 -0.00531 -0.11 -0.4122 -0.8504 1399613 IFLab1_004579 COc1cccc2cc(C(=O)NC3CCCCC3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A04 compound treatment 0.337 0.012 0.47 0.344 0.0147 0.31 0.551 0.9784 2067956 IFLab1_004580 COc1ccc(c2n[nH]c(c2c3cnn(c3)c4ccccc4)C(F)(F)F)c(O)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A05 compound treatment 0.33 0.005 0.2 0.338 0.00869 0.18 0.2676 0.9992 1423467 IFLab1_004581 O=C(COc1ccccc1)Nc2sc3CCCCc3c2C(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A06 compound treatment 0.341 0.016 0.63 0.342 0.0127 0.27 0.6326 0.9264 2067957 IFLab1_004582 CCc1cc2c(=O)c(Oc3ccccc3F)c(oc2c(CN(C)C)c1O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A07 compound treatment 0.331 0.006 0.24 0.342 0.0127 0.27 0.3546 0.9983 1436811 IFLab1_004583 COc1ccc(Cl)cc1S(=O)(=O)NCCN2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A08 compound treatment 0.362 0.037 1.45 0.327 -0.00231 -0.05 0.9945 0.6832 1374298 IFLab1_004584 OCCCc1nc2ccccc2n1Cc3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A09 compound treatment 0.326 0.001 0.04 0.325 -0.00431 -0.09 -0.036 -0.3658 2067958 IFLab1_004585 Cc1cc(C)nc(SC(C#N)c2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A10 compound treatment 0.328 0.003 0.12 0.346 0.0167 0.35 0.3303 0.8962 2067959 IFLab1_004586 OC(=O)CC1S/C(=N/c2ccccc2)/N(C1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A11 compound treatment 0.33 0.005 0.2 0.331 0.00169 0.04 0.164 0.821 2067960 IFLab1_004587 CC1=CC(=O)/C(=C/Nc2cccc(c2)C(F)(F)F)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A12 compound treatment 0.356 0.031 1.22 0.337 0.00769 0.16 0.9756 0.7936 1638905 IFLab1_004588 O=C(CC1SC(=O)NC1=O)Nc2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A13 compound treatment 0.336 0.011 0.43 0.336 0.00669 0.14 0.4048 0.8905 2067961 IFLab1_004589 O=C(CN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A14 compound treatment 0.33 0.005 0.2 0.358 0.0287 0.6 0.5635 0.8921 1276376 IFLab1_004590 Oc1cccc2CCCN(c12)S(=O)(=O)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A15 compound treatment 0.335 0.01 0.39 0.335 0.00569 0.12 0.3622 0.8816 2067962 IFLab1_004591 CCOc1ccccc1NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A16 compound treatment 0.32 -0.005 -0.2 0.324 -0.00531 -0.11 -0.2176 -0.9636 2067963 IFLab1_004592 C=CCn1c(SCC(=O)c2ccccc2)nnc1c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A17 compound treatment 0.299 -0.026 -1.02 0.299 -0.0303 -0.63 -1.1714 -0.9737 2067964 IFLab1_004593 O=C(CCCN1C(=O)/C(=C/C=C/c2ccccc2)/SC1=S)NC3=NCCS3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A18 compound treatment 0.327 0.002 0.08 0.328 -0.00131 -0.03 0.0362 0.4344 1275009 IFLab1_004594 OC(=O)Cc1cc(=O)oc2c1ccc3ccccc32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A19 compound treatment 0.331 0.006 0.24 0.358 0.0287 0.6 0.5913 0.9167 1331110 IFLab1_004595 O=C(Cc1cccs1)Nc2ccc(cc2)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A20 compound treatment 0.345 0.02 0.79 0.322 -0.00731 -0.15 0.4478 0.559 1565168 IFLab1_004596 Oc1ccc(CN2CCN(CC2)c3ccc(F)cc3)c4cccnc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A21 compound treatment 0.332 0.007 0.28 0.322 -0.00731 -0.15 0.0864 0.2744 1587927 IFLab1_004597 Cc1ccc(cc1)N2C(=O)C3C4OC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A22 compound treatment 0.328 0.003 0.12 0.328 -0.00131 -0.03 0.064 0.5283 1701435 IFLab1_004598 CCOC(=O)c1c(C)oc2c1c3CN(CCO)COc3c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A23 mock treatment 0.317 -0.008 -0.31 0.317 -0.0123 -0.26 -0.4046 -0.9951 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 A24 positive control 0.081 -0.244 -9.59 0.08 -0.249 -5.22 -10.4728 -0.959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B01 compound treatment 0.333 0.008 0.31 0.344 0.0147 0.31 0.4397 0.9999 1488289 IFLab1_004599 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NC4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B02 compound treatment 0.315 -0.01 -0.39 0.323 -0.00631 -0.13 -0.3714 -0.8955 1352342 IFLab1_004600 COc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B03 compound treatment 0.321 -0.004 -0.16 0.329 -3.12E-4 -0.01 -0.1158 -0.7359 1158402 IFLab1_004601 CC1CN(CC(C)O1)c2oc(nc2C#N)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B04 compound treatment 0.324 -0.001 -0.04 0.345 0.0157 0.33 0.2043 0.618 2067965 IFLab1_004602 OC(=O)C(CC(=O)Nc1ccccc1)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B05 compound treatment 0.353 0.028 1.1 0.386 0.0567 1.19 1.6173 0.9993 1554471 IFLab1_004603 Clc1ccc(Nc2nc(CC(=O)NCc3ccccc3)cs2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B06 compound treatment 0.322 -0.003 -0.12 0.357 0.0277 0.58 0.3263 0.5518 2067966 IFLab1_004604 CC(C)NC(CC(=O)Nc1ccc(C)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B07 compound treatment 0.33 0.005 0.2 0.389 0.0597 1.25 1.0222 0.8084 1419715 IFLab1_004605 Cn1c(=NC(=O)c2ccc(Cl)s2)sc3cc(ccc13)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B08 compound treatment 0.327 0.002 0.08 0.355 0.0257 0.54 0.4357 0.802 1382065 IFLab1_004606 COc1ccccc1N2CCN(CC(O)COc3c(F)cc(Br)cc3F)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B09 compound treatment 0.349 0.024 0.94 0.381 0.0517 1.08 1.4321 0.9977 1237175 IFLab1_004607 NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B10 compound treatment 0.327 0.002 0.08 0.383 0.0537 1.12 0.85 0.7548 1480977 IFLab1_004608 CC(C)C(NC(=O)C1(CC2(C)CC3(C)CC(C)(C2)C1)C3)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B11 compound treatment 0.365 0.04 1.57 0.397 0.0677 1.42 2.1137 0.9986 1296257 IFLab1_004609 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(F)cc2)C#N)c3cccs3)C(=O)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B12 compound treatment 0.312 -0.013 -0.51 0.334 0.00469 0.1 -0.2921 -0.5612 1181255 IFLab1_004610 OC(=O)CNC(=O)CC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B13 compound treatment 0.352 0.027 1.06 0.384 0.0547 1.14 1.5599 0.9993 1500326 IFLab1_004611 CCN(CC)S(=O)(=O)c1ccc2SC(=O)c3cccc1c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B14 compound treatment 0.343 0.018 0.71 0.369 0.0397 0.83 1.0877 0.9968 1610407 IFLab1_004612 COc1cc(Cl)c(cc1Cl)S(=O)(=O)Nc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B15 compound treatment 0.325 0.0 0.0 0.364 0.0347 0.73 0.5133 0.7071 1626661 IFLab1_004613 CCOC(Cn1c(CO)nc2ccccc12)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B16 compound treatment 0.373 0.048 1.89 0.394 0.0647 1.35 2.2917 0.9867 2067967 IFLab1_004614 O=C1C(=Cc2ccco2)C(=O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B17 compound treatment 0.339 0.014 0.55 0.358 0.0287 0.6 0.8137 0.9991 2067968 IFLab1_004615 O/N=C/c1nc(c2ccccc2)n3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B18 compound treatment 0.342 0.017 0.67 0.357 0.0277 0.58 0.8823 0.9975 1487281 IFLab1_004616 CC1(C)C2CCC1(CS(=O)(=O)N3CCN(CC3)c4ccccc4F)C(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B19 compound treatment 0.265 -0.06 -2.36 0.274 -0.0553 -1.16 -2.4866 -0.9463 1388984 IFLab1_004617 CCN1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B20 compound treatment 0.355 0.03 1.18 0.343 0.0137 0.29 1.0366 0.854 1328803 IFLab1_004618 Cc1ccc(o1)c2c3CCCCc3nc4sc(C(=O)N)c(N)c24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B21 compound treatment 0.351 0.026 1.02 0.357 0.0277 0.58 1.1325 0.9638 2067969 IFLab1_004619 Brc1ccc(/C=C/C(=O)\C=C\c2ccc(Br)o2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B22 compound treatment 0.335 0.01 0.39 0.315 -0.0143 -0.3 0.0662 0.134 2067970 IFLab1_004620 COc1ccc(cc1)C(=O)CSc2nc(C)c(C(=O)N)c(C)c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B23 mock treatment 0.328 0.003 0.12 0.322 -0.00731 -0.15 -0.0248 -0.1283 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 B24 positive control 0.08 -0.245 -9.63 0.079 -0.25 -5.24 -10.5154 -0.959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C01 compound treatment 0.367 0.042 1.65 0.37 0.0407 0.85 1.7697 0.9525 1867103 IFLab1_004621 O=S(=O)(/C=C/c1ccccc1)N2CCN(CC2)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C02 compound treatment 0.288 -0.037 -1.45 0.283 -0.0463 -0.97 -1.714 -0.9805 2067971 IFLab1_004622 NC(=O)/C=C/C(=O)Nc1ccc(cc1)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C03 compound treatment 0.331 0.006 0.24 0.417 0.0877 1.83 1.4643 0.7915 1531823 IFLab1_004623 CN(C)C(=O)c1cc2cccc(CC=C)c2oc1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C04 compound treatment 0.345 0.02 0.79 0.428 0.0987 2.07 2.0163 0.9124 1712547 IFLab1_004624 COc1ccc2c(=O)c(Oc3ccccc3F)c(C)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C05 compound treatment 0.334 0.009 0.35 0.426 0.0967 2.02 1.6809 0.8184 2067972 IFLab1_004625 COc1nc(nc(Cl)c1NC(=O)c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C06 compound treatment 0.344 0.019 0.75 0.426 0.0967 2.02 1.9589 0.9083 1139894 IFLab1_004626 CC12CS(=O)(=O)CC2SC(=S)N1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C07 compound treatment 0.336 0.011 0.43 0.419 0.0897 1.88 1.6329 0.8478 2067973 IFLab1_004627 COc1cc(c(OC)cc1Br)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C08 compound treatment 0.328 0.003 0.12 0.434 0.105 2.19 1.6325 0.7441 1214357 IFLab1_004628 C(Cn1cnc2ccccc12)Oc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C09 compound treatment 0.326 0.001 0.04 0.452 0.123 2.57 1.8432 0.7179 2067974 IFLab1_004629 Cc1sc2nc(SCc3ccc(cc3)C(=O)NCCO)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C10 compound treatment 0.325 0.0 0.0 0.44 0.111 2.32 1.6379 0.7071 2067975 IFLab1_004630 Oc1ccc(/N=C/2\NC(=O)CS2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C11 compound treatment 0.343 0.018 0.71 0.426 0.0967 2.02 1.9311 0.9009 1425224 IFLab1_004631 COc1ccc(cc1OC)C(=O)Oc2c(C)occc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C12 compound treatment 0.354 0.029 1.14 0.43 0.101 2.11 2.2961 0.9584 2067976 IFLab1_004632 O=C(Nc1ccccc1)/C=C/2\SC(=O)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C13 compound treatment 0.351 0.026 1.02 0.467 0.138 2.88 2.7602 0.9028 2067977 IFLab1_004633 O=C(CN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C14 compound treatment 0.327 0.002 0.08 0.429 0.0997 2.09 1.5307 0.7332 1224768 IFLab1_004634 COc1ccc(cc1)S(=O)(=O)N2CCCc3cccc(O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C15 compound treatment 0.371 0.046 1.81 0.481 0.152 3.17 3.5234 0.9644 2067978 IFLab1_004635 CCOc1ccc(NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C16 compound treatment 0.324 -0.001 -0.04 0.405 0.0757 1.58 1.0922 0.6893 1635746 IFLab1_004636 COc1ccc(cc1)N2CCN(CC(O)COc3ccccc3CC=C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C17 compound treatment 0.359 0.034 1.34 0.476 0.147 3.07 3.1158 0.9306 2067979 IFLab1_004637 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCCC(=O)Nc3cccnc3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C18 compound treatment 0.348 0.023 0.9 0.431 0.102 2.13 2.1441 0.9273 2067980 IFLab1_004638 Brc1ccc(NC(=O)c2cccs2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C19 compound treatment 0.346 0.021 0.83 0.421 0.0917 1.92 1.9406 0.929 1174397 IFLab1_004639 Cc1cccc(N2C(=O)CC(N(O)c3ccccc3)C2=O)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C20 compound treatment 0.341 0.016 0.63 0.431 0.102 2.13 1.9495 0.8786 1196000 IFLab1_004640 Oc1ccc(CNc2ccc(Cl)cn2)c3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C21 compound treatment 0.337 0.012 0.47 0.404 0.0747 1.56 1.4388 0.8813 1653982 IFLab1_004641 Cc1ccc(N2C(=O)CC(Sc3ccccc3C(=O)O)C2=O)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C22 compound treatment 0.327 0.002 0.08 0.359 0.0297 0.62 0.4949 0.7903 1636765 IFLab1_004642 COc1ccc(CCN2COc3c(C2)cc(Cl)c4cccnc34)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C23 mock treatment 0.323 -0.002 -0.08 0.321 -0.00831 -0.17 -0.1786 -0.9356 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 C24 positive control 0.081 -0.244 -9.59 0.078 -0.251 -5.26 -10.5024 -0.96 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D01 compound treatment 0.379 0.054 2.12 0.383 0.0537 1.12 2.2957 0.9557 1670351 IFLab1_004643 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D02 compound treatment 0.316 -0.009 -0.35 0.321 -0.00831 -0.17 -0.3732 -0.9465 2067981 IFLab1_004644 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)NC2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D03 compound treatment 0.333 0.008 0.31 0.424 0.0947 1.98 1.6235 0.8092 1552352 IFLab1_004645 CN1CCN(CC1)c2oc(nc2C#N)c3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D04 compound treatment 0.338 0.013 0.51 0.412 0.0827 1.73 1.585 0.8785 2067982 IFLab1_004646 OC(=O)C(CC(=O)Nc1ccccc1)NCCC2=CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D05 compound treatment 0.334 0.009 0.35 0.421 0.0917 1.92 1.6069 0.8236 1268870 IFLab1_004647 COc1ccc(OC)c(NC(=O)CCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D06 compound treatment 0.336 0.011 0.43 0.426 0.0967 2.02 1.7365 0.8393 1258179 IFLab1_004648 CC(C)c1ccccc1OCC(O)CN2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D07 compound treatment 0.345 0.02 0.79 0.436 0.107 2.23 2.1347 0.9019 1163664 IFLab1_004649 Cn1c(=NC(=O)c2c(F)cccc2F)sc3cc(ccc13)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D08 compound treatment 0.33 0.005 0.2 0.436 0.107 2.23 1.7177 0.7664 1213728 IFLab1_004650 COc1ccccc1N2CCN(CC(O)COc3ccccc3C(C)(C)C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D09 compound treatment 0.338 0.013 0.51 0.446 0.117 2.44 2.0881 0.837 1121939 IFLab1_004651 CCOC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D10 compound treatment 0.335 0.01 0.39 0.408 0.0787 1.65 1.4424 0.852 1611471 IFLab1_004652 Cc1ccc(cc1)C2(CC3CC4CC(C3)(C2)C(=O)NCC(=O)O)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D11 compound treatment 0.374 0.049 1.93 0.516 0.187 3.91 4.1247 0.9469 2067983 IFLab1_004653 Brc1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D12 compound treatment 0.338 0.013 0.51 0.459 0.13 2.71 2.2804 0.8258 1193720 IFLab1_004654 CC(C)C(NC(=O)CC1(CC2CC3CC(C2)C1)C3)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D13 compound treatment 0.343 0.018 0.71 0.457 0.128 2.67 2.3898 0.8646 1133429 IFLab1_004655 OC(=O)c1cccc(c1)S(=O)(=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D14 compound treatment 0.332 0.007 0.28 0.437 0.108 2.25 1.7881 0.7876 1425263 IFLab1_004656 COc1c(Cl)c(Cl)ccc1S(=O)(=O)Nc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D15 compound treatment 0.336 0.011 0.43 0.436 0.107 2.23 1.8845 0.8287 1701281 IFLab1_004657 CCOC(Cn1c(nc2ccccc12)C(C)O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D16 compound treatment 0.348 0.023 0.9 0.466 0.137 2.86 2.662 0.8874 2067984 IFLab1_004658 Cc1sc2nc(SCc3nnc(Nc4ccccc4)s3)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D17 compound treatment 0.436 0.111 4.36 0.528 0.199 4.16 6.026 0.9997 2067985 IFLab1_004659 OC(=O)/C=C/c1nc(c2ccccc2)n3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D18 compound treatment 0.336 0.011 0.43 0.433 0.104 2.17 1.8401 0.8317 2067986 IFLab1_004660 Cc1cc(C)n(n1)c2nc(nc3ccccc23)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D19 compound treatment 0.28 -0.045 -1.77 0.364 0.0347 0.73 -0.7378 -0.3858 1243310 IFLab1_004661 Cc1[nH]c2ccccc2c1C(N3CCC(CC3)C(=O)N)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D20 compound treatment 0.374 0.049 1.93 0.453 0.124 2.59 3.1925 0.9894 2067987 IFLab1_004662 Brc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D21 compound treatment 0.348 0.023 0.9 0.423 0.0937 1.96 2.0258 0.9383 1610342 IFLab1_004663 Oc1cc(c2ccc(Cl)cc2Cl)c3oc(=O)sc3c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D22 compound treatment 0.343 0.018 0.71 0.359 0.0297 0.62 0.9397 0.9979 1672509 IFLab1_004664 O=C(CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccco3)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D23 mock treatment 0.321 -0.004 -0.16 0.324 -0.00531 -0.11 -0.1898 -0.9856 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 D24 positive control 0.083 -0.242 -9.51 0.08 -0.249 -5.22 -10.4172 -0.96 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E01 compound treatment 0.327 0.002 0.08 0.336 0.00669 0.14 0.1546 0.9628 1328309 IFLab1_004665 CCCOC(=O)c1cccc(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E02 compound treatment 0.314 -0.011 -0.43 0.32 -0.00931 -0.19 -0.4436 -0.9352 1419652 IFLab1_004666 O=S(=O)(N1CCCc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E03 compound treatment 0.322 -0.003 -0.12 0.397 0.0677 1.42 0.9182 0.646 1629177 IFLab1_004667 OC(=O)c1ccccc1C(=O)NCc2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E04 compound treatment 0.334 0.009 0.35 0.419 0.0897 1.88 1.5773 0.8259 1206695 IFLab1_004668 CN(C)Cc1c(O)ccc2c(=O)c(c3cnn(c3)c4ccccc4)c(C)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E05 compound treatment 0.333 0.008 0.31 0.411 0.0817 1.71 1.4312 0.8234 1574212 IFLab1_004669 CCOc1ccc(cc1)S(=O)(=O)NCc2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E06 compound treatment 0.329 0.004 0.16 0.428 0.0987 2.07 1.5715 0.7588 2067988 IFLab1_004670 CCN(CC)C(=S)SC1=C(Cl)CS(=O)(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E07 compound treatment 0.331 0.006 0.24 0.436 0.107 2.23 1.7455 0.7775 1143921 IFLab1_004671 COc1cc(c(OC)cc1Br)S(=O)(=O)N2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E08 compound treatment 0.336 0.011 0.43 0.446 0.117 2.44 2.0325 0.8196 2067989 IFLab1_004672 CCc1nc2ccccc2n1CCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E09 compound treatment 0.367 0.042 1.65 0.472 0.143 2.99 3.279 0.961 2067990 IFLab1_004673 CCOC(=O)CSc1nc(N)c2c3CCCc3sc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E10 compound treatment 0.512 0.187 7.35 0.609 0.28 5.85 9.3375 0.9936 2067991 IFLab1_004674 OC(=O)CCCN1C(=O)S/C(=C\C=C\c2ccccc2)/C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E11 compound treatment 0.343 0.018 0.71 0.459 0.13 2.71 2.4194 0.8627 1052339 IFLab1_004675 OCc1cc(=O)c(O)c(CN2CCOCC2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E12 compound treatment 0.369 0.044 1.73 0.47 0.141 2.94 3.3051 0.9679 2067992 IFLab1_004676 O=C(Nc1nccs1)/C=C/2\SC(=O)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E13 compound treatment 0.348 0.023 0.9 0.479 0.15 3.13 2.8544 0.8755 2067993 IFLab1_004677 O=C(CN1C(=O)/C(=C\c2cccs2)/SC1=S)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E14 compound treatment 0.339 0.014 0.55 0.443 0.114 2.38 2.0715 0.8483 2067994 IFLab1_004678 CC1CCN(CC1)S(=O)(=O)c2ccc(Cl)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E15 compound treatment 0.392 0.067 2.63 0.491 0.162 3.38 4.2552 0.9923 2067995 IFLab1_004679 FC(F)(F)c1ccccc1NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E16 compound treatment 0.329 0.004 0.16 0.437 0.108 2.25 1.7047 0.7546 1224542 IFLab1_004680 COc1ccc(cc1)N2CCN(CC(O)COC3C(C)(C)C4CCC3(C)C4)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E17 compound treatment 0.333 0.008 0.31 0.452 0.123 2.57 2.0378 0.7878 2067996 IFLab1_004681 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCCC(=O)Nc3cc(C)on3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E18 compound treatment 0.338 0.013 0.51 0.436 0.107 2.23 1.9401 0.8471 1047188 IFLab1_004682 Clc1ccc(cc1Cl)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E19 compound treatment 0.345 0.02 0.79 0.424 0.0947 1.98 1.9571 0.9181 2067997 IFLab1_004683 O=C(Nc1ccc(cc1)N2CCOCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E20 compound treatment 0.362 0.037 1.45 0.429 0.0997 2.09 2.5038 0.9845 1132054 IFLab1_004684 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NC4CC(C)(C)NC(C)(C)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E21 compound treatment 0.277 -0.048 -1.89 0.345 0.0157 0.33 -1.1024 -0.5755 2067998 IFLab1_004685 [O-]/[N+](=C\c1ccc(F)cc1)/c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E22 compound treatment 0.346 0.021 0.83 0.38 0.0507 1.06 1.3339 0.9923 1283697 IFLab1_004686 Clc1cc2CN(COc2c3ncccc13)C4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E23 mock treatment 0.32 -0.005 -0.2 0.32 -0.00931 -0.19 -0.2768 -1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 E24 positive control 0.084 -0.241 -9.48 0.082 -0.247 -5.18 -10.3598 -0.9595 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F01 compound treatment 0.351 0.026 1.02 0.356 0.0267 0.56 1.1177 0.9596 1370382 IFLab1_004687 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F02 compound treatment 0.322 -0.003 -0.12 0.313 -0.0163 -0.34 -0.3248 -0.8993 2067999 IFLab1_004688 OC(=O)C(CC(=O)Nc1cccc(Cl)c1Cl)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F03 compound treatment 0.346 0.021 0.83 0.433 0.104 2.17 2.1181 0.9124 1125272 IFLab1_004689 Fc1ccccc1c2nc(C#N)c(NC3CCCCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F04 compound treatment 0.316 -0.009 -0.35 0.41 0.0807 1.69 0.9437 0.547 2068000 IFLab1_004690 OC(=O)C(CC(=O)Nc1ccccc1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F05 compound treatment 0.328 0.003 0.12 0.409 0.0797 1.67 1.2626 0.7552 2068001 IFLab1_004691 C=CC/N=C/1\SCC(=O)N1S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F06 compound treatment 0.331 0.006 0.24 0.423 0.0937 1.96 1.5531 0.7865 1514657 IFLab1_004692 CC(C)c1ccccc1OCC(O)CN2CC(C)OC(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F07 compound treatment 0.325 0.0 0.0 0.425 0.0957 2.0 1.4159 0.7071 2068002 IFLab1_004693 COc1ccc(Cl)cc1NC(=O)/C(=C\C(=O)O)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F08 compound treatment 0.353 0.028 1.1 0.456 0.127 2.65 2.6531 0.9242 1639934 IFLab1_004694 CCCc1cc(NCCN(C)C)n2c3ccccc3nc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F09 compound treatment 0.334 0.009 0.35 0.454 0.125 2.61 2.0952 0.7957 1413907 IFLab1_004695 CCOC(=O)c1sc2nc3CCCC(=O)c3cc2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F10 compound treatment 0.345 0.02 0.79 0.426 0.0967 2.02 1.9867 0.9152 1594347 IFLab1_004696 Cc1ccc(cc1)C(=O)NCC(=O)NC2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F11 compound treatment 0.348 0.023 0.9 0.502 0.173 3.61 3.1947 0.8576 2068003 IFLab1_004697 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F12 compound treatment 0.351 0.026 1.02 0.448 0.119 2.48 2.4791 0.923 1173735 IFLab1_004698 Cc1ccc(c(C)c1C)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F13 compound treatment 0.343 0.018 0.71 0.462 0.133 2.78 2.4638 0.8598 1200595 IFLab1_004699 COc1ccc(NS(=O)(=O)c2cccc(c2)C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F14 compound treatment 0.347 0.022 0.86 0.443 0.114 2.38 2.2939 0.9062 1675115 IFLab1_004700 COc1c(Cl)c(Cl)ccc1S(=O)(=O)n2cnc(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F15 compound treatment 0.348 0.023 0.9 0.436 0.107 2.23 2.2181 0.9208 1471952 IFLab1_004701 CCOC(Cn1c(COc2ccccc2)nc3ccccc13)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F16 compound treatment 0.353 0.028 1.1 0.45 0.121 2.53 2.5643 0.9308 1263925 IFLab1_004702 Cc1sc2ncnc(Nc3ccc(F)cc3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F17 compound treatment 0.345 0.02 0.79 0.434 0.105 2.19 2.1051 0.9044 1451270 IFLab1_004703 OC(c1cccs1)c2nccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F18 compound treatment 0.349 0.024 0.94 0.452 0.123 2.57 2.4827 0.9076 1321579 IFLab1_004704 Cc1noc(C)c1COc2ccc3ccc(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F19 compound treatment 0.341 0.016 0.63 0.408 0.0787 1.65 1.6092 0.9129 2068004 IFLab1_004705 CC1=CC(=O)/C(=C/Nc2cccc(F)c2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F20 compound treatment 0.352 0.027 1.06 0.442 0.113 2.36 2.4181 0.9351 1509495 IFLab1_004706 Cc1ccc(NC(=O)CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F21 compound treatment 0.341 0.016 0.63 0.421 0.0917 1.92 1.8015 0.8922 1124052 IFLab1_004707 Oc1cc(c2ccc(F)cc2)c3oc(=O)sc3c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F22 compound treatment 0.345 0.02 0.79 0.403 0.0737 1.54 1.6464 0.9512 1692546 IFLab1_004708 CCc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F23 mock treatment 0.319 -0.006 -0.24 0.316 -0.0133 -0.28 -0.3638 -0.9966 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 F24 positive control 0.083 -0.242 -9.51 0.082 -0.247 -5.18 -10.3876 -0.959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G01 compound treatment 0.33 0.005 0.2 0.327 -0.00231 -0.05 0.1048 0.5176 1683742 IFLab1_004709 Cc1cc(C)nc(SCC(CSc2nc(C)cc(C)n2)C(=O)O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G02 compound treatment 0.309 -0.016 -0.63 0.31 -0.0193 -0.4 -0.7306 -0.9771 2068005 IFLab1_004710 COc1ccc(NC(=O)CC2SC(=N)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G03 compound treatment 0.367 0.042 1.65 0.443 0.114 2.38 2.8499 0.9841 2068006 IFLab1_004711 FC(F)(F)C(=C(C#N)C#N)Nc1ccccn1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G04 compound treatment 0.343 0.018 0.71 0.408 0.0787 1.65 1.6648 0.9289 1718602 IFLab1_004712 CN(C)Cc1cc2c(=O)c(c3cnn(c3)c4ccccc4)c(C)oc2c(C)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G05 compound treatment 0.311 -0.014 -0.55 0.402 0.0727 1.52 0.6863 0.4243 1612106 IFLab1_004713 Clc1ccc(Cl)c(c1)S(=O)(=O)NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G06 compound treatment 0.332 0.007 0.28 0.408 0.0787 1.65 1.359 0.814 1212778 IFLab1_004714 COc1ccccc1NC2CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G07 compound treatment 0.324 -0.001 -0.04 0.434 0.105 2.19 1.5213 0.6943 1321934 IFLab1_004715 COc1cccc2cc(C(=O)N3CCN(CC3)c4ccccc4)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G08 compound treatment 0.325 0.0 0.0 0.422 0.0927 1.94 1.3715 0.7071 1724423 IFLab1_004716 CC(O)c1nc2ccccc2n1CCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G09 compound treatment 0.331 0.006 0.24 0.461 0.132 2.76 2.1154 0.7648 1579401 IFLab1_004717 COc1ccc(cc1)C(=O)N2CCN(CCn3c(C)ccc3C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G10 compound treatment 0.337 0.012 0.47 0.425 0.0957 2.0 1.7495 0.8504 2068007 IFLab1_004718 OC(=O)/C=C/1\SC(=O)NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G11 compound treatment 0.335 0.01 0.39 0.464 0.135 2.82 2.271 0.798 2068008 IFLab1_004719 Cc1cccnc1N/C=C/2\C(=O)Oc3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G12 compound treatment 0.274 -0.051 -2.01 0.428 0.0987 2.07 0.0424 0.0147 1297968 IFLab1_004720 CC(C)Cn1c(NN)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G13 compound treatment 0.348 0.023 0.9 0.452 0.123 2.57 2.4549 0.9019 2068009 IFLab1_004721 O=C(CN1C(=O)/C(=C\c2cccs2)/SC1=S)N3CCN(CC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G14 compound treatment 0.317 -0.008 -0.31 0.436 0.107 2.23 1.3563 0.6015 1641682 IFLab1_004722 Clc1ccc(s1)S(=O)(=O)N2CCN(CC2)S(=O)(=O)c3ccc(Cl)s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G15 compound treatment 0.232 -0.093 -3.66 0.412 0.0827 1.73 -1.3621 -0.3367 2068010 IFLab1_004723 Clc1ccc(NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G16 compound treatment 0.325 0.0 0.0 0.416 0.0867 1.81 1.2827 0.7071 1648540 IFLab1_004724 CC1(C)C(OCC(O)CN2CCN(CC2)c3cccc(Cl)c3)C4(C)CCC1C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G17 compound treatment 0.322 -0.003 -0.12 0.475 0.146 3.05 2.0723 0.6792 2068011 IFLab1_004725 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CC(=O)Nc3cccnc3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G18 compound treatment 0.333 0.008 0.31 0.422 0.0927 1.94 1.5939 0.8112 1337253 IFLab1_004726 CN(CC(O)COCc1ccc2OCOc2c1)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G19 compound treatment 0.303 -0.022 -0.86 0.392 0.0627 1.31 0.3159 0.2011 2068012 IFLab1_004727 Cc1ccccc1/[N+](=C/c2ccncc2)/[O-] 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G20 compound treatment 0.337 0.012 0.47 0.428 0.0987 2.07 1.7939 0.8468 1648175 IFLab1_004728 CCOC(=O)c1c(C)oc2c1c(CN3CCN(C)CC3)c(O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G21 compound treatment 0.34 0.015 0.59 0.418 0.0887 1.86 1.7293 0.8881 2068013 IFLab1_004729 FC(F)(F)c1cccc(c1)N2C(=O)CC(Nc3ccc(cc3)N4CCOCC4)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G22 compound treatment 0.338 0.013 0.51 0.395 0.0657 1.37 1.3334 0.9092 1271328 IFLab1_004730 Clc1cc2CN(CCCN3CCOCC3)COc2c4ncccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G23 mock treatment 0.318 -0.007 -0.28 0.321 -0.00831 -0.17 -0.3176 -0.9755 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 G24 positive control 0.083 -0.242 -9.51 0.082 -0.247 -5.18 -10.3876 -0.959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H01 compound treatment 0.362 0.037 1.45 0.358 0.0287 0.6 1.4532 0.9234 1679577 IFLab1_004731 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CC(C)OC(C)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H02 compound treatment 0.317 -0.008 -0.31 0.318 -0.0113 -0.24 -0.3898 -0.9902 2068014 IFLab1_004732 NC(CC(=O)Nc1ccc(Cl)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H03 compound treatment 0.321 -0.004 -0.16 0.398 0.0687 1.44 0.9052 0.626 1204754 IFLab1_004733 COc1ccc(cc1)c2nc(C#N)c(o2)N3CC(C)OC(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H04 compound treatment 0.328 0.003 0.12 0.4 0.0707 1.48 1.1294 0.7611 2068015 IFLab1_004734 OC(=O)C(CC(=O)Nc1ccccc1)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H05 compound treatment 0.361 0.036 1.42 0.452 0.123 2.57 2.8163 0.9606 1574049 IFLab1_004735 OCCNC(=O)c1ccc(CSc2nc3sc4CCCc4c3c(=O)[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H06 compound treatment 0.334 0.009 0.35 0.419 0.0897 1.88 1.5773 0.8259 1471476 IFLab1_004736 CC(C)c1ccccc1OCC(O)CN(C)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H07 compound treatment 0.36 0.035 1.38 0.491 0.162 3.38 3.3656 0.9214 1313936 IFLab1_004737 COc1ccc2oc(=Nc3ccccc3)c(cc2c1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H08 compound treatment 0.337 0.012 0.47 0.441 0.112 2.34 1.9863 0.833 1627175 IFLab1_004738 C1CCN(C1)c2ncnc3scc(c4ccccc4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H09 compound treatment 0.351 0.026 1.02 0.425 0.0957 2.0 2.1388 0.9513 1702530 IFLab1_004739 CC1(C)CC(=O)c2cc(C#N)c(SCC=C)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H10 compound treatment 0.325 0.0 0.0 0.448 0.119 2.48 1.7562 0.7071 1411984 IFLab1_004740 CC(NC(=O)c1ccc(C)cc1)C(=O)NC2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H11 compound treatment 0.346 0.021 0.83 0.471 0.142 2.96 2.6804 0.8709 2068016 IFLab1_004741 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H12 compound treatment 0.351 0.026 1.02 0.485 0.156 3.26 3.0266 0.8864 1535363 IFLab1_004742 COc1ccc(OC)c(c1)S(=O)(=O)NC2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H13 compound treatment 0.35 0.025 0.98 0.45 0.121 2.53 2.4809 0.9154 1417274 IFLab1_004743 O=C(Oc1ccc2ccc(=O)oc2c1)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H14 compound treatment 0.354 0.029 1.14 0.467 0.138 2.88 2.8436 0.9177 1295540 IFLab1_004744 Brc1ccc2oc(=O)c(cc2c1)C(=O)OCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H15 compound treatment 0.34 0.015 0.59 0.449 0.12 2.5 2.1881 0.8504 1312039 IFLab1_004745 CCCCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H16 compound treatment 0.33 0.005 0.2 0.456 0.127 2.65 2.0136 0.7575 1285134 IFLab1_004746 Cc1sc2ncnc(Nc3ccc4OCOc4c3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H17 compound treatment 0.351 0.026 1.02 0.438 0.109 2.27 2.3311 0.9348 2068017 IFLab1_004747 CCOC(=O)c1ccc(N/C=C\2/C(=O)OC(=CC2=O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H18 compound treatment 0.339 0.014 0.55 0.428 0.0987 2.07 1.8495 0.8654 1237999 IFLab1_004748 COC(=O)c1c(NC(=O)CCN2CCC(C)CC2)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H19 compound treatment 0.34 0.015 0.59 0.435 0.106 2.21 1.9809 0.8654 2068018 IFLab1_004749 CC1=CC(=O)/C(=C/Nc2ccccc2Br)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H20 compound treatment 0.328 0.003 0.12 0.42 0.0907 1.9 1.4253 0.7496 1271820 IFLab1_004750 CCc1ccc(NC(=O)CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H21 compound treatment 0.352 0.027 1.06 0.432 0.103 2.15 2.2701 0.9472 2068019 IFLab1_004751 Cc1ccc(cc1)C(=O)CC(c2cccs2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H22 compound treatment 0.338 0.013 0.51 0.416 0.0867 1.81 1.6442 0.8724 1429648 IFLab1_004752 COc1ccc(cc1OC)C2C(=C(NC(=C2C(=O)Nc3ccccc3C)C)SC)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H23 mock treatment 0.323 -0.002 -0.08 0.332 0.00269 0.06 -0.0158 -0.1638 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 H24 positive control 0.086 -0.239 -9.4 0.083 -0.246 -5.15 -10.2894 -0.96 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I01 compound treatment 0.343 0.018 0.71 0.334 0.00469 0.1 0.5698 0.7975 1523731 IFLab1_004753 CC1(CC2C(C(=O)NCC=C)C(=O)N1)Oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I02 compound treatment 0.396 0.071 2.79 0.423 0.0937 1.96 3.3602 0.9851 1479951 IFLab1_004754 O=C(CC1Sc2ccccc2NC1=O)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I03 compound treatment 0.321 -0.004 -0.16 0.404 0.0747 1.56 0.994 0.6328 1480556 IFLab1_004755 CCCOC1(NC(=O)c2ccc(C)cc2)C(=CC(=O)C=C1C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I04 compound treatment 0.346 0.021 0.83 0.405 0.0757 1.58 1.7038 0.9539 1218950 IFLab1_004756 CN(C)Cc1cc2c(=O)c(Oc3ccccc3F)c(C)oc2c(C)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I05 compound treatment 0.333 0.008 0.31 0.421 0.0917 1.92 1.5791 0.8122 1403868 IFLab1_004757 COc1cc(ccc1Cl)S(=O)(=O)Nc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I06 compound treatment 0.359 0.034 1.34 0.451 0.122 2.55 2.7459 0.9548 2068020 IFLab1_004758 O=S1(=O)CC2SC(=S)N(Cc3ccccc3)C2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I07 compound treatment 0.372 0.047 1.85 0.454 0.125 2.61 3.1517 0.9857 2068021 IFLab1_004759 CCc1ccc(/N=C/c2c(O)ccc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I08 compound treatment 0.327 0.002 0.08 0.449 0.12 2.5 1.8266 0.7289 2068022 IFLab1_004760 OCCCc1nc2ccccc2n1CCCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I09 compound treatment 0.355 0.03 1.18 0.437 0.108 2.25 2.4275 0.9544 1686056 IFLab1_004761 Cc1oc2c(cc(O)c3ccccc23)c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I10 compound treatment 0.409 0.084 3.3 0.528 0.199 4.16 5.2754 0.9935 2068023 IFLab1_004762 Oc1cccc(NC(=O)CCCN2C(=O)S/C(=C\C=C\c3ccccc3)/C2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I11 compound treatment 0.325 0.0 0.0 0.497 0.168 3.51 2.4813 0.7071 1293366 IFLab1_004763 Cc1cc2cc(NC(=O)c3ccco3)ccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I12 compound treatment 0.339 0.014 0.55 0.479 0.15 3.13 2.6042 0.8188 1729635 IFLab1_004764 CCOC(Cn1c(C)nc2ccccc12)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I13 compound treatment 0.359 0.034 1.34 0.487 0.158 3.3 3.2786 0.9209 2068024 IFLab1_004765 O=C(CN1C(=O)/C(=C\c2cccs2)/SC1=S)N(Cc3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I14 compound treatment 0.334 0.009 0.35 0.435 0.106 2.21 1.8141 0.8099 1279880 IFLab1_004766 CC1CCc2ccccc2N1S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I15 compound treatment 0.25 -0.075 -2.95 0.387 0.0577 1.21 -1.2315 -0.3865 2068025 IFLab1_004767 O=C(CCCN1C(=O)/C(=C\c2ccco2)/SC1=S)Nc3ccc4ccccc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I16 compound treatment 0.352 0.027 1.06 0.435 0.106 2.21 2.3145 0.9435 1609431 IFLab1_004768 CC1CC(CC(C)(C)C1)OCC(O)CN2CCN(CC2)c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I17 compound treatment 0.331 0.006 0.24 0.48 0.151 3.15 2.3966 0.7579 2068026 IFLab1_004769 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CC(=O)Nc3ccccn3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I18 compound treatment 0.323 -0.002 -0.08 0.418 0.0887 1.86 1.2567 0.6765 1577195 IFLab1_004770 CN(CC(O)COCC1COc2ccccc2O1)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I19 compound treatment 0.322 -0.003 -0.12 0.433 0.104 2.17 1.4509 0.6677 2068027 IFLab1_004771 CC1=CC(=O)N(CCC#N)c2ccccc2N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I20 compound treatment 0.341 0.016 0.63 0.438 0.109 2.27 2.0531 0.87 2068028 IFLab1_004772 CCOC(=O)c1c(C)oc-2c1/C(=C/NCc3ccccn3)/C(=O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I21 compound treatment 0.348 0.023 0.9 0.43 0.101 2.11 2.1293 0.9287 2068029 IFLab1_004773 COc1cc(/C=N\S(=O)(=O)c2cccs2)cc(Br)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I22 compound treatment 0.336 0.011 0.43 0.449 0.12 2.5 2.0769 0.8171 1446470 IFLab1_004774 CN1CCN(Cc2c(c(C)c3ccccn23)c4ccccc4)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I23 mock treatment 0.331 0.006 0.24 0.344 0.0147 0.31 0.3841 0.9915 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 I24 positive control 0.088 -0.237 -9.32 0.083 -0.246 -5.15 -10.2338 -0.961 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J01 compound treatment 0.358 0.033 1.3 0.357 0.0277 0.58 1.3272 0.934 1614018 IFLab1_004775 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CCN(CC)CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J02 compound treatment 0.318 -0.007 -0.28 0.317 -0.0123 -0.26 -0.3768 -0.9995 2068030 IFLab1_004776 OC(=O)C(CC(=O)Nc1ccc(Cl)cc1)NCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J03 compound treatment 0.318 -0.007 -0.28 0.383 0.0537 1.12 0.5998 0.5185 1372168 IFLab1_004777 Clc1ccccc1c2nc(C#N)c(o2)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J04 compound treatment 0.324 -0.001 -0.04 0.385 0.0557 1.17 0.7962 0.6829 2068031 IFLab1_004778 COc1ccccc1NC(=O)CC(NCc2ccccc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J05 compound treatment 0.326 0.001 0.04 0.392 0.0627 1.31 0.9554 0.728 1639457 IFLab1_004779 CC(=O)N=c1sc2cc(ccc2n1C)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J06 compound treatment 0.327 0.002 0.08 0.403 0.0737 1.54 1.146 0.7422 1391862 IFLab1_004780 CC(C)c1ccccc1OCC(O)CN2C(C)(C)CC(O)CC2(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J07 compound treatment 0.333 0.008 0.31 0.427 0.0977 2.04 1.6679 0.8064 1459734 IFLab1_004781 CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J08 compound treatment 0.331 0.006 0.24 0.424 0.0947 1.98 1.5679 0.7857 1593253 IFLab1_004782 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(Cl)cc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J09 compound treatment 0.362 0.037 1.45 0.48 0.151 3.15 3.2584 0.9383 1514613 IFLab1_004783 Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J10 compound treatment 0.328 0.003 0.12 0.433 0.104 2.17 1.6177 0.7444 1203559 IFLab1_004784 CC(C)CC(NC(=O)c1ccc(C)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J11 compound treatment 0.364 0.039 1.53 0.537 0.208 4.35 4.1575 0.9021 1691430 IFLab1_004785 Cc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J12 compound treatment 0.341 0.016 0.63 0.488 0.159 3.32 2.7929 0.8264 1466915 IFLab1_004786 COc1ccc(Cl)cc1S(=O)(=O)NC2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J13 compound treatment 0.336 0.011 0.43 0.453 0.124 2.59 2.136 0.814 1660049 IFLab1_004787 CC(=O)Oc1ccc(cc1)N(C(=O)C)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J14 compound treatment 0.335 0.01 0.39 0.429 0.0997 2.09 1.7531 0.8258 1635047 IFLab1_004788 CC1CN(CC(C)O1)C(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J15 compound treatment 0.321 -0.004 -0.16 0.441 0.112 2.34 1.5414 0.658 1277840 IFLab1_004789 O=C1CC(CN1c2ccccc2)c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J16 compound treatment 0.329 0.004 0.16 0.462 0.133 2.78 2.0746 0.746 2068032 IFLab1_004790 COC(=O)c1c(NC(=O)CCN2CC(C)OC(C)C2)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J17 compound treatment 0.326 0.001 0.04 0.435 0.106 2.21 1.5917 0.7196 1548974 IFLab1_004791 COc1ccc(NC(c2c(C)[nH]c3ccccc23)c4ccccn4)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J18 compound treatment 0.345 0.02 0.79 0.433 0.104 2.17 2.0903 0.9057 1259190 IFLab1_004792 OCCNc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J19 compound treatment 0.34 0.015 0.59 0.458 0.129 2.69 2.3212 0.842 2068033 IFLab1_004793 CC1=CC(=O)/C(=C/Nc2ccc(C)cc2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J20 compound treatment 0.351 0.026 1.02 0.455 0.126 2.63 2.5827 0.9152 2068034 IFLab1_004794 Clc1ccc(NC(=O)CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J21 compound treatment 0.356 0.031 1.22 0.453 0.124 2.59 2.6921 0.941 2068035 IFLab1_004795 Cc1ccc(cc1)c2ccc(/C=N/n3cnnc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J22 compound treatment 0.347 0.022 0.86 0.445 0.116 2.42 2.3235 0.9038 1272038 IFLab1_004796 Cc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J23 mock treatment 0.324 -0.001 -0.04 0.348 0.0187 0.39 0.2487 0.6328 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 J24 positive control 0.09 -0.235 -9.24 0.084 -0.245 -5.13 -10.1634 -0.9615 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K01 compound treatment 0.348 0.023 0.9 0.338 0.00869 0.18 0.768 0.8326 1731947 IFLab1_004797 O=C(N1CC(=O)Nc2ccccc12)c3cc4ccccc4oc3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K02 compound treatment 0.32 -0.005 -0.2 0.323 -0.00631 -0.13 -0.2324 -0.9813 1219728 IFLab1_004798 COC(=O)c1c(NC(=O)CC2Sc3ccccc3NC2=O)sc4CCCCc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K03 compound treatment 0.316 -0.009 -0.35 0.358 0.0287 0.6 0.1743 0.2501 1253240 IFLab1_004799 Cc1cc(NC(=O)Cc2ccccc2)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K04 compound treatment 0.397 0.072 2.83 0.482 0.153 3.2 4.2611 0.9982 1392397 IFLab1_004800 CCc1cc2c(=O)c(c3cnn(c3)c4ccccc4)c(C)oc2cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K05 compound treatment 0.319 -0.006 -0.24 0.378 0.0487 1.02 0.5536 0.5294 1412463 IFLab1_004801 COc1cc(ccc1Cl)S(=O)(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K06 compound treatment 0.336 0.011 0.43 0.393 0.0637 1.33 1.2482 0.8908 2068036 IFLab1_004802 COC(=O)C(C1CCS(=O)(=O)C1)S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K07 compound treatment 0.332 0.007 0.28 0.393 0.0637 1.33 1.137 0.8355 1599104 IFLab1_004803 Oc1ccccc1c2csc(n2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K08 compound treatment 0.342 0.017 0.67 0.423 0.0937 1.96 1.8589 0.8975 2068037 IFLab1_004804 OCc1nc2ccccc2n1CCCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K09 compound treatment 0.343 0.018 0.71 0.411 0.0817 1.71 1.7092 0.9238 2068038 IFLab1_004805 CC1=CC(=O)/C(=C/Nc2ccccn2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K10 compound treatment 0.419 0.094 3.7 0.511 0.182 3.8 5.3018 0.9999 2068039 IFLab1_004806 Oc1ccc(NC(=O)CN2C(=O)S/C(=C\C=C\c3ccccc3)/C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K11 compound treatment 0.327 0.002 0.08 0.453 0.124 2.59 1.8858 0.7283 1342138 IFLab1_004807 CC1CN(Cc2oc(CO)cc(=O)c2O)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K12 compound treatment 0.34 0.015 0.59 0.472 0.143 2.99 2.5284 0.8307 2068040 IFLab1_004808 CC(=C)Cn1c(nc2ccccc12)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K13 compound treatment 0.325 0.0 0.0 0.541 0.212 4.43 3.1324 0.7071 2068041 IFLab1_004809 COc1ccccc1NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K14 compound treatment 0.339 0.014 0.55 0.449 0.12 2.5 2.1603 0.8424 1596879 IFLab1_004810 O=S(=O)(NCCN1CCOCC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K15 compound treatment 0.377 0.052 2.04 0.532 0.203 4.24 4.4449 0.944 2068042 IFLab1_004811 Cc1csc(NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K16 compound treatment 0.342 0.017 0.67 0.446 0.117 2.44 2.1993 0.8687 1177055 IFLab1_004812 COc1ccc(OCC(O)Cn2cnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K17 compound treatment 0.363 0.038 1.49 0.515 0.186 3.89 3.8041 0.9138 2068043 IFLab1_004813 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CC(=O)N3CCN(CC3)c4ccccc4)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K18 compound treatment 0.37 0.045 1.77 0.493 0.164 3.43 3.6732 0.9528 1336607 IFLab1_004814 CCc1c(C)c(C#N)c2nc3ccccc3n2c1NCCN(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K19 compound treatment 0.346 0.021 0.83 0.478 0.149 3.11 2.784 0.8648 2068044 IFLab1_004815 Cc1ccc(/C=[N+](\[O-])/c2ccccc2C)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K20 compound treatment 0.329 0.004 0.16 0.435 0.106 2.21 1.6751 0.7555 2068045 IFLab1_004816 CCOC(=O)c1c(C)oc-2c1/C(=C/NCc3cccnc3)/C(=O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K21 compound treatment 0.351 0.026 1.02 0.435 0.106 2.21 2.2867 0.9385 2068046 IFLab1_004817 N=C1NC(=O)C(CC(=O)Nc2ccc(cc2)N3CCCCC3)S1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K22 compound treatment 0.318 -0.007 -0.28 0.434 0.105 2.19 1.3545 0.6134 1413048 IFLab1_004818 CCOC(=O)c1c(C)oc2c1c(CN3CCN(CC)CC3)c(O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K23 mock treatment 0.324 -0.001 -0.04 0.35 0.0207 0.43 0.2783 0.6403 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 K24 positive control 0.089 -0.236 -9.28 0.086 -0.243 -5.09 -10.1616 -0.9601 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L01 compound treatment 0.343 0.018 0.71 0.342 0.0127 0.27 0.6882 0.9104 1673825 IFLab1_004819 Cc1[nH]c2ccccc2c1C(O)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L02 compound treatment 0.311 -0.014 -0.55 0.316 -0.0133 -0.28 -0.5862 -0.9502 2068047 IFLab1_004820 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)NCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L03 compound treatment 0.404 0.079 3.11 0.403 0.0737 1.54 3.2867 0.9478 1329589 IFLab1_004821 COc1ccc(Nc2oc(nc2C#N)c3ccccc3Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L04 compound treatment 0.319 -0.006 -0.24 0.354 0.0247 0.52 0.1985 0.3495 2068048 IFLab1_004822 Cc1ccccc1NC(=O)CC(NCc2ccccc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L05 compound treatment 0.349 0.024 0.94 0.428 0.0987 2.07 2.1275 0.937 1599499 IFLab1_004823 COc1cccc(c1)C(=O)N=c2sc3cc(ccc3n2C)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L06 compound treatment 0.32 -0.005 -0.2 0.382 0.0527 1.1 0.6406 0.572 1577554 IFLab1_004824 CCC(C)c1ccccc1OCC(O)CNC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L07 compound treatment 0.344 0.019 0.75 0.406 0.0767 1.6 1.663 0.9395 1280637 IFLab1_004825 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)cc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L08 compound treatment 0.402 0.077 3.03 0.476 0.147 3.07 4.3113 1.0 1216919 IFLab1_004826 OC1=C(C(N(Cc2cccnc2)C1=O)c3ccc(F)cc3)C(=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L09 compound treatment 0.343 0.018 0.71 0.413 0.0837 1.75 1.7388 0.9205 1733784 IFLab1_004827 CCOC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(cc3)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L10 compound treatment 0.334 0.009 0.35 0.401 0.0717 1.5 1.311 0.8506 1422056 IFLab1_004828 COc1ccc(cc1)C(=O)NCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L11 compound treatment 0.326 0.001 0.04 0.413 0.0837 1.75 1.2661 0.7228 2068049 IFLab1_004829 O=S(=O)(N1CCOCC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L12 compound treatment 0.333 0.008 0.31 0.453 0.124 2.59 2.0526 0.7872 2068050 IFLab1_004830 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cc(Cl)ccc2OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L13 compound treatment 0.345 0.02 0.79 0.457 0.128 2.67 2.4454 0.878 2068051 IFLab1_004831 NC(=O)CCn1cnc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L14 compound treatment 0.365 0.04 1.57 0.466 0.137 2.86 3.1347 0.9603 2068052 IFLab1_004832 COc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L15 compound treatment 0.341 0.016 0.63 0.494 0.165 3.45 2.8817 0.8226 1136508 IFLab1_004833 C(Cn1c(nc2ccccc12)c3ccco3)Oc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L16 compound treatment 0.344 0.019 0.75 0.471 0.142 2.96 2.6248 0.8584 2068053 IFLab1_004834 COc1ccc(cc1)c2csc3ncnc(n4nc(C)cc4N)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L17 compound treatment 0.341 0.016 0.63 0.464 0.135 2.82 2.4378 0.8442 1334590 IFLab1_004835 Cc1cc(NC(c2c(C)[nH]c3ccccc23)c4ccccn4)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L18 compound treatment 0.353 0.028 1.1 0.453 0.124 2.59 2.6087 0.9275 1699433 IFLab1_004836 C=CCSc1nnc(o1)c2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L19 compound treatment 0.344 0.019 0.75 0.426 0.0967 2.02 1.9589 0.9083 1314063 IFLab1_004837 Clc1ccc(cc1)C(=O)Oc2c(CN3CCOCC3)cc(Cl)c4cccnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L20 compound treatment 0.36 0.035 1.38 0.434 0.105 2.19 2.5221 0.9749 1271753 IFLab1_004838 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccccc2Cl)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L21 compound treatment 0.342 0.017 0.67 0.418 0.0887 1.86 1.785 0.9049 1449299 IFLab1_004839 Cc1ccc(CCC(=O)Nc2ccc(cc2)C(=O)O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L22 compound treatment 0.356 0.031 1.22 0.412 0.0827 1.73 2.0854 0.9853 1301330 IFLab1_004840 CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(OCc4ccccc4)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L23 mock treatment 0.328 0.003 0.12 0.34 0.0107 0.22 0.2416 0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 L24 positive control 0.09 -0.235 -9.24 0.086 -0.243 -5.09 -10.1338 -0.9606 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M01 compound treatment 0.323 -0.002 -0.08 0.332 0.00269 0.06 -0.0158 -0.1638 2068054 IFLab1_004841 CC(=O)N1CC(=O)Nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M02 compound treatment 0.328 0.003 0.12 0.333 0.00369 0.08 0.138 0.9788 1454506 IFLab1_004842 COC(=O)c1c(C)c(C)sc1NC(=O)CC2Sc3ccccc3NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M03 compound treatment 0.32 -0.005 -0.2 0.329 -3.12E-4 -0.01 -0.1436 -0.7302 1540390 IFLab1_004843 COC1(NC(=O)c2ccccc2)C(=CC(=O)C=C1C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M04 compound treatment 0.327 0.002 0.08 0.355 0.0257 0.54 0.4357 0.802 1681787 IFLab1_004844 CCc1cc2c(=O)c(c(C)oc2cc1OCC(=O)O)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M05 compound treatment 0.334 0.009 0.35 0.356 0.0267 0.56 0.6451 0.9758 1373556 IFLab1_004845 COc1cc(C)ccc1S(=O)(=O)n2cnc3cc(C)c(C)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M06 compound treatment 0.32 -0.005 -0.2 0.373 0.0437 0.91 0.5074 0.5426 1638669 IFLab1_004846 CN(C(=O)c1ccc(Cl)cc1)C2(C)CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M07 compound treatment 0.489 0.164 6.45 0.532 0.203 4.24 7.5587 0.9794 2068055 IFLab1_004847 O=C/1NC(=S)S\C1=C/Nc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M08 compound treatment 0.351 0.026 1.02 0.397 0.0677 1.42 1.7244 0.9872 2068056 IFLab1_004848 Cc1nc2ccccc2n1CCCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M09 compound treatment 0.344 0.019 0.75 0.398 0.0687 1.44 1.5446 0.9535 2068057 IFLab1_004849 Cc1cc(O)c(/C=N/c2ccccn2)c(=O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M10 compound treatment 0.342 0.017 0.67 0.419 0.0897 1.88 1.7997 0.9034 2068058 IFLab1_004850 NC(=O)CC1SC(=O)NC1=N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M11 compound treatment 0.363 0.038 1.49 0.434 0.105 2.19 2.6055 0.9826 1679062 IFLab1_004851 Cc1ccc(C)n1CCN2CCN(CC2)C(=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M12 compound treatment 0.339 0.014 0.55 0.433 0.104 2.17 1.9235 0.8593 1635935 IFLab1_004852 CCCn1c(nc2ccccc12)c3ccc(cc3)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M13 compound treatment 0.37 0.045 1.77 0.551 0.222 4.64 4.5314 0.9127 2068059 IFLab1_004853 COc1cccc(NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M14 compound treatment 0.32 -0.005 -0.2 0.462 0.133 2.78 1.8244 0.6554 1365021 IFLab1_004854 COc1ccc(cc1OC)C2CC(=O)n3nc(nc3S2)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M15 compound treatment 0.258 -0.067 -2.63 0.43 0.101 2.11 -0.3729 -0.1105 2068060 IFLab1_004855 Fc1cccc(NC(=O)CCCN2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M16 compound treatment 0.347 0.022 0.86 0.457 0.128 2.67 2.501 0.8905 1353446 IFLab1_004856 Cc1ccc2c(CC(=O)O)cc(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M17 compound treatment 0.35 0.025 0.98 0.473 0.144 3.01 2.8212 0.8918 2068061 IFLab1_004857 CCNC(=O)CC1Sc2ccc(cc2NC1=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M18 compound treatment 0.355 0.03 1.18 0.44 0.111 2.32 2.4719 0.951 1175381 IFLab1_004858 Cc1c(CCC#N)c(O)n2c3ccccc3nc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M19 compound treatment 0.182 -0.143 -5.62 0.239 -0.0903 -1.89 -5.3121 -0.8956 2068062 IFLab1_004859 O=C1C=CC(=O)N1c2ccccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M20 compound treatment 0.359 0.034 1.34 0.408 0.0787 1.65 2.1096 0.9947 2068063 IFLab1_004860 CCOC(=O)c1c(C)oc-2c1/C(=C/NCC3CCCO3)/C(=O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M21 compound treatment 0.308 -0.017 -0.67 0.378 0.0487 1.02 0.2478 0.2034 1389116 IFLab1_004861 CCNC(=O)CC1Nc2cc(C)c(C)cc2NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M22 compound treatment 0.352 0.027 1.06 0.385 0.0557 1.17 1.5747 0.9989 1354410 IFLab1_004862 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)Nc4ccc(C)cn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M23 mock treatment 0.335 0.01 0.39 0.333 0.00369 0.08 0.3326 0.83 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 M24 positive control 0.092 -0.233 -9.16 0.088 -0.241 -5.05 -10.0486 -0.9606 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N01 compound treatment 0.324 -0.001 -0.04 0.327 -0.00231 -0.05 -0.062 -0.9947 1348243 IFLab1_004863 Fc1ccccc1c2nc(C#N)c(NCCN3CCOCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N02 compound treatment 0.313 -0.012 -0.47 0.313 -0.0163 -0.34 -0.575 -0.9874 2068064 IFLab1_004864 Cc1cccc(C)c1NC(=O)CC(NCc2ccco2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N03 compound treatment 0.315 -0.01 -0.39 0.32 -0.00931 -0.19 -0.4158 -0.9476 1144471 IFLab1_004865 CN(C)CCNc1oc(nc1C#N)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N04 compound treatment 0.317 -0.008 -0.31 0.339 0.00969 0.2 -0.0791 -0.2113 2068065 IFLab1_004866 COc1ccccc1NC(=O)CC(N(C)C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N05 compound treatment 0.366 0.041 1.61 0.389 0.0597 1.25 2.0231 0.992 1631308 IFLab1_004867 Cn1c(=NC(=O)c2cccc3ccccc23)sc4cc(ccc14)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N06 compound treatment 0.334 0.009 0.35 0.35 0.0207 0.43 0.5563 0.995 1636718 IFLab1_004868 CCC(C)c1ccccc1OCC(O)CN2CCN(Cc3ccc4OCOc4c3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N07 compound treatment 0.366 0.041 1.61 0.393 0.0637 1.33 2.0823 0.9955 1582749 IFLab1_004869 COc1cc(ccc1O)C2C(=C(NC3=C2C(=O)CCC3)SCc4ccccc4)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N08 compound treatment 0.378 0.053 2.08 0.42 0.0907 1.9 2.8154 0.9989 1529622 IFLab1_004870 OC1=C(C(N(Cc2cccnc2)C1=O)c3ccncc3)C(=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N09 compound treatment 0.36 0.035 1.38 0.414 0.0847 1.77 2.2262 0.9922 1714926 IFLab1_004871 CC(C)c1ccc(cc1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)N)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N10 compound treatment 0.339 0.014 0.55 0.395 0.0657 1.37 1.3612 0.9193 1655271 IFLab1_004872 CC(C)C(NC(=O)COc1ccccc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N11 compound treatment 0.355 0.03 1.18 0.408 0.0787 1.65 1.9984 0.9866 2068066 IFLab1_004873 O=S(=O)(N1CCCCC1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N12 compound treatment 0.352 0.027 1.06 0.404 0.0747 1.56 1.8558 0.9822 1728353 IFLab1_004874 CC(C)c1ccc(C)c(c1)S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N13 compound treatment 0.357 0.032 1.26 0.447 0.118 2.46 2.6311 0.9514 1056487 IFLab1_004875 CCOC(CSc1nc2ccccc2[nH]1)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N14 compound treatment 0.363 0.038 1.49 0.46 0.131 2.73 2.9903 0.9596 2068067 IFLab1_004876 CS/C(=C/1\CCCCC1=O)/NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N15 compound treatment 0.337 0.012 0.47 0.424 0.0947 1.98 1.7347 0.8517 1513471 IFLab1_004877 Nc1ccc(cc1)c2nc3ccccc3n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N16 compound treatment 0.337 0.012 0.47 0.443 0.114 2.38 2.0159 0.8312 1648406 IFLab1_004878 CC1CCc2c(C1)sc3ncnc(NCCN4CCOCC4)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N17 compound treatment 0.328 0.003 0.12 0.414 0.0847 1.77 1.3365 0.7525 1185990 IFLab1_004879 CC1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N18 compound treatment 0.346 0.021 0.83 0.399 0.0697 1.46 1.615 0.9637 1349673 IFLab1_004880 Cc1cc(C)n(n1)C(=O)C2CCCN2S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N19 compound treatment 0.323 -0.002 -0.08 0.379 0.0497 1.04 0.6796 0.6518 1283648 IFLab1_004881 Cc1[nH]c2ccccc2c1C(N3CCCCC3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N20 compound treatment 0.342 0.017 0.67 0.386 0.0567 1.19 1.3114 0.9632 1412058 IFLab1_004882 CCOC(=O)CSC1=C(C#N)C(C)C2=C(CCCC2=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N21 compound treatment 0.353 0.028 1.1 0.382 0.0527 1.1 1.5581 1.0 1341013 IFLab1_004883 CN(C1CCCCC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N22 compound treatment 0.377 0.052 2.04 0.395 0.0657 1.37 2.4177 0.9813 1230304 IFLab1_004884 CCSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(OCc4ccccc4)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N23 mock treatment 0.332 0.007 0.28 0.328 -0.00131 -0.03 0.1752 0.6334 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 N24 positive control 0.093 -0.232 -9.12 0.089 -0.24 -5.03 -10.006 -0.9606 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O01 compound treatment 0.385 0.06 2.36 0.375 0.0457 0.96 2.3442 0.9209 1683671 IFLab1_004885 COc1cccc(NC(=O)c2cc3cccc(CC=C)c3oc2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O02 compound treatment 0.377 0.052 2.04 0.377 0.0477 1.0 2.1513 0.9456 2068068 IFLab1_004886 Oc1ccc(c2n[nH]c(c2c3cnn(c3)c4ccccc4)C(F)(F)F)c(O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O03 compound treatment 0.306 -0.019 -0.75 0.31 -0.0193 -0.4 -0.814 -0.9584 1578971 IFLab1_004887 COc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O04 compound treatment 0.315 -0.01 -0.39 0.313 -0.0163 -0.34 -0.5194 -0.9975 1295379 IFLab1_004888 CCc1cc2c(=O)c(Oc3ccccc3F)c(C)oc2cc1OCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O05 compound treatment 0.31 -0.015 -0.59 0.315 -0.0143 -0.3 -0.6288 -0.9506 1082126 IFLab1_004889 Cc1ccc(NC(=O)c2ccco2)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O06 compound treatment 0.319 -0.006 -0.24 0.322 -0.00731 -0.15 -0.275 -0.978 2068069 IFLab1_004890 Cc1nc2ccc(Br)cc2c(c3ccccc3)c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O07 compound treatment 0.459 0.134 5.27 0.446 0.117 2.44 5.4521 0.9389 2068070 IFLab1_004891 CCN1C(=O)/C(=C/Nc2nc3ccccc3[nH]2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O08 compound treatment 0.325 0.0 0.0 0.328 -0.00131 -0.03 -0.0194 -0.7071 1320029 IFLab1_004892 ONC(=O)c1sc2ccccc2c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O09 compound treatment 0.321 -0.004 -0.16 0.326 -0.00331 -0.07 -0.1602 -0.9322 2068071 IFLab1_004893 Cc1cc(O)c(/C=N/c2ccc(I)cc2)c(=O)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O10 compound treatment 0.33 0.005 0.2 0.335 0.00569 0.12 0.2232 0.9711 2068072 IFLab1_004894 COC(=O)CC/1SC(=O)N\C1=N\c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O11 compound treatment 0.38 0.055 2.16 0.364 0.0347 0.73 2.0424 0.8954 1458878 IFLab1_004895 Cc1ccc(C)n1CCN2CCN(CC2)C(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O12 compound treatment 0.345 0.02 0.79 0.344 0.0147 0.31 0.7734 0.916 1191331 IFLab1_004896 Oc1cccc2CCCN(c12)S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O13 compound treatment 0.376 0.051 2.01 0.375 0.0457 0.96 2.0939 0.9426 2068073 IFLab1_004897 COc1ccc(NC(=O)CCCN2C(=O)/C(=C\c3ccco3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O14 compound treatment 0.33 0.005 0.2 0.351 0.0217 0.45 0.4599 0.9299 2068074 IFLab1_004898 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O15 compound treatment 0.264 -0.061 -2.4 0.277 -0.0523 -1.09 -2.47 -0.9369 2068075 IFLab1_004899 O=C(CCCN1C(=O)/C(=C/C=C/c2ccccc2)/SC1=S)Nc3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O16 compound treatment 0.344 0.019 0.75 0.361 0.0317 0.66 0.9971 0.9982 1040166 IFLab1_004900 OC(=O)Cc1cc(=O)oc2cc(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O17 compound treatment 0.355 0.03 1.18 0.359 0.0297 0.62 1.2733 0.9552 2068076 IFLab1_004901 Oc1ccc2ccccc2c1/C=N/S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O18 compound treatment 0.342 0.017 0.67 0.338 0.00869 0.18 0.6012 0.8679 2068077 IFLab1_004902 Clc1ccc(cc1)c2csc3ncnc(Cl)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O19 compound treatment 0.336 0.011 0.43 0.339 0.00969 0.2 0.4492 0.9404 1404527 IFLab1_004903 CC(=O)Oc1ccc(cc1)N2C(=O)C3C4OC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O20 compound treatment 0.346 0.021 0.83 0.34 0.0107 0.22 0.742 0.8674 2068078 IFLab1_004904 CCOC(=O)c1c(C)oc-2c1/C(=C/NCc3ccco3)/C(=O)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O21 compound treatment 0.33 0.005 0.2 0.344 0.0147 0.31 0.3563 0.9767 2068079 IFLab1_004905 COC(=O)c1c(C)c(C)sc1N2C(=O)C3CC(=C(C)CC3C2=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O22 compound treatment 0.375 0.05 1.97 0.374 0.0447 0.94 2.0513 0.9423 1566101 IFLab1_004906 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)Nc4cccc(C)n4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O23 mock treatment 0.328 0.003 0.12 0.323 -0.00631 -0.13 -0.01 -0.0565 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 O24 positive control 0.096 -0.229 -9.0 0.091 -0.238 -4.99 -9.893 -0.9612 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P01 compound treatment 0.352 0.027 1.06 0.343 0.0137 0.29 0.9532 0.8669 1424679 IFLab1_004907 Fc1ccccc1c2nc(C#N)c(NCCc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P02 compound treatment 0.325 0.0 0.0 0.319 -0.0103 -0.22 -0.1526 -0.7071 2068080 IFLab1_004908 CN(C)C(CC(=O)Nc1c(C)cccc1C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P03 compound treatment 0.326 0.001 0.04 0.323 -0.00631 -0.13 -0.0656 -0.476 1921619 IFLab1_004909 OC(=O)/C=C\C(=O)Nc1ccc(Cl)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P04 compound treatment 0.336 0.011 0.43 0.343 0.0137 0.29 0.5084 0.98 2068081 IFLab1_004910 Cc1ccc(C)c(NC(=O)CC(NCCc2ccccc2)C(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P05 compound treatment 0.346 0.021 0.83 0.346 0.0167 0.35 0.8308 0.9267 1647669 IFLab1_004911 Cn1c(=NC(=O)c2ccco2)sc3cc(ccc13)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P06 compound treatment 0.363 0.038 1.49 0.342 0.0127 0.27 1.2442 0.8199 1630888 IFLab1_004912 CCC(OCC(O)CN1CCCC1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P07 compound treatment 0.37 0.045 1.77 0.373 0.0437 0.91 1.8975 0.9528 1335997 IFLab1_004913 CCSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P08 compound treatment 0.377 0.052 2.04 0.385 0.0557 1.17 2.2697 0.9645 1579335 IFLab1_004914 Cc1ccc(cc1)C2N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4ccccc4)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P09 compound treatment 0.378 0.053 2.08 0.37 0.0407 0.85 2.0756 0.922 1438643 IFLab1_004915 COC(=O)C1C(C(=C(NC1=O)SCc2ccccc2Cl)C#N)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P10 compound treatment 0.377 0.052 2.04 0.376 0.0467 0.98 2.1365 0.9429 1199415 IFLab1_004916 OC(=O)C(Cc1ccccc1)NC(=O)COc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P11 compound treatment 0.361 0.036 1.42 0.366 0.0367 0.77 1.5437 0.9587 2068082 IFLab1_004917 COc1ccccc1NS(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P12 compound treatment 0.363 0.038 1.49 0.36 0.0307 0.64 1.5106 0.9289 1301866 IFLab1_004918 COc1cc(Cl)c(cc1Cl)S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P13 compound treatment 0.366 0.041 1.61 0.376 0.0467 0.98 1.8307 0.9712 1205579 IFLab1_004919 CCOC(Cn1c(nc2ccccc12)c3ccc(OC)cc3)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P14 compound treatment 0.377 0.052 2.04 0.366 0.0367 0.77 1.9886 0.9105 1094785 IFLab1_004920 Oc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P15 compound treatment 0.358 0.033 1.3 0.355 0.0257 0.54 1.2976 0.9239 1345180 IFLab1_004921 CCn1c(nc2ccccc12)c3ccc(N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P16 compound treatment 0.362 0.037 1.45 0.353 0.0237 0.5 1.3792 0.8974 2068083 IFLab1_004922 Cc1noc(C)c1CN2CCN(CC2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P17 compound treatment 0.322 -0.003 -0.12 0.318 -0.0113 -0.24 -0.2508 -0.9482 1461963 IFLab1_004923 CCOC(=O)C1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P18 compound treatment 0.376 0.051 2.01 0.379 0.0497 1.04 2.1531 0.9532 2068084 IFLab1_004924 Cc1c(O)ccc(c2n[nH]c(c2Oc3ccccc3)C(F)(F)F)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P19 compound treatment 0.357 0.032 1.26 0.359 0.0297 0.62 1.329 0.9471 2068085 IFLab1_004925 COc1ccccc1C2CC(=O)CC(S2)c3ccccc3OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P20 compound treatment 0.328 0.003 0.12 0.342 0.0127 0.27 0.2711 0.9333 1268872 IFLab1_004926 CC1=C(C(C(=C(N1)SCC(=O)c2ccccc2)C#N)c3ccco3)C(=O)Nc4ccccc4C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P21 compound treatment 0.341 0.016 0.63 0.343 0.0137 0.29 0.6474 0.9366 1451347 IFLab1_004927 CN(C1CCCCC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P22 compound treatment 0.352 0.027 1.06 0.349 0.0197 0.41 1.042 0.915 1261725 IFLab1_004928 NC(=O)c1sc2NC(=O)CC(c2c1N)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P23 mock treatment 0.329 0.004 0.16 0.33 6.88E-4 0.01 0.1214 0.7686 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1425 P24 positive control 0.1 -0.225 -8.85 0.094 -0.235 -4.92 -9.7374 -0.9617 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A01 compound treatment 0.34 0.0154 0.6 0.349 0.0259 0.54 0.8113 0.9986 1331393 IFLab1_004929 COc1ccc(cc1)C2C(=C(NC3=C2C(=O)CC(C)(C)C3)SCC(=O)Nc4ccccc4)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A02 compound treatment 0.312 -0.0126 -0.5 0.328 0.00494 0.1 -0.2779 -0.5482 1299912 IFLab1_004930 CC1CCN(CC1)C(=O)c2ccc(cc2)C(=O)N3CCC(C)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A03 compound treatment 0.337 0.0124 0.49 0.341 0.0179 0.38 0.6095 0.9918 1234075 IFLab1_004931 CCOc1ccccc1C2C(=C(NC3=C2C(=O)CCC3)SC)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A04 compound treatment 0.35 0.0254 1.0 0.331 0.00794 0.17 0.8229 0.8136 1623784 IFLab1_004932 C(Sc1ccccn1)c2cn3cccnc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A05 compound treatment 0.33 0.00538 0.21 0.343 0.0199 0.42 0.4445 0.9503 1145453 IFLab1_004933 COC(=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A06 compound treatment 0.331 0.00638 0.25 0.331 0.00794 0.17 0.2947 0.98 1460803 IFLab1_004934 Cc1cc(Cl)ccc1OCc2cn3cccnc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A07 compound treatment 0.328 0.00338 0.13 0.323 -6.25E-5 0.0 0.0929 0.7001 1458206 IFLab1_004935 CC1CN(CC(C)O1)c2nnnn2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A08 compound treatment 0.326 0.00138 0.05 0.322 -0.00106 -0.02 0.0225 0.385 1516662 IFLab1_004936 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)COc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A09 compound treatment 0.352 0.0274 1.08 0.323 -6.25E-5 0.0 0.7602 0.7062 2068086 IFLab1_004937 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A10 compound treatment 0.327 0.00238 0.09 0.33 0.00694 0.15 0.1687 0.9772 1134486 IFLab1_004938 COc1ccc(NC(=O)CSc2nc3CCCC(=O)c3cc2C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A11 compound treatment 0.33 0.00538 0.21 0.327 0.00394 0.08 0.2077 0.9157 2068087 IFLab1_004939 CC1CN(CCC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A12 compound treatment 0.34 0.0154 0.6 0.354 0.0309 0.65 0.8852 0.9994 1638070 IFLab1_004940 CCN(CC)C(=O)c1sc2nc3CC(C)(C)CC(=O)c3cc2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A13 compound treatment 0.353 0.0284 1.12 0.327 0.00394 0.08 0.8471 0.7573 1253964 IFLab1_004941 C1CN(CCO1)c2nnc(c3cccs3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A14 compound treatment 0.322 -0.00262 -0.1 0.328 0.00494 0.1 1.0E-4 6.0E-4 2068088 IFLab1_004942 Cc1cc(C)c(C#N)c(SCc2cn3c(C)cccc3n2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A15 compound treatment 0.33 0.00538 0.21 0.351 0.0279 0.58 0.5628 0.9054 1676583 IFLab1_004943 Cc1sc2ncnc(NCc3ccc4OCOc4c3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A16 compound treatment 0.35 0.0254 1.0 0.351 0.0279 0.58 1.1189 0.9676 1583138 IFLab1_004944 COC(=O)Cc1cc(=O)oc2cc(O)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A17 compound treatment 0.339 0.0144 0.57 0.319 -0.00406 -0.09 0.3395 0.5941 1667885 IFLab1_004945 CCOC(=O)c1c(NC(=O)CCN2CCOCC2)sc(C)c1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A18 compound treatment 0.324 -6.25E-4 -0.02 0.323 -6.25E-5 0.0 -0.0183 -0.7437 1057190 IFLab1_004946 O=C(N1CCOCC1)c2c3CCCCc3nc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A19 compound treatment 0.315 -0.00962 -0.38 0.347 0.0239 0.5 0.0866 0.138 1398007 IFLab1_004947 Cc1cc(=O)oc2cc(Oc3nncc4ccccc34)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A20 compound treatment 0.348 0.0234 0.92 0.321 -0.00206 -0.04 0.6194 0.6732 2068089 IFLab1_004948 COc1cccc(NC(=O)CC2SC(=N)NC2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A21 compound treatment 0.318 -0.00662 -0.26 0.316 -0.00706 -0.15 -0.2887 -0.964 1328045 IFLab1_004949 O=C(CSc1nnc2ccccn12)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A22 compound treatment 0.318 -0.00662 -0.26 0.323 -6.25E-5 0.0 -0.1851 -0.7106 1584108 IFLab1_004950 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NC4CCSC4=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A23 mock treatment 0.316 -0.00862 -0.34 0.314 -0.00906 -0.19 -0.3739 -0.9623 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 A24 positive control 0.079 -0.246 -9.66 0.079 -0.244 -5.11 -10.4403 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B01 compound treatment 0.334 0.00938 0.37 0.338 0.0149 0.31 0.4817 0.9966 1420417 IFLab1_004951 COc1ccc(cc1)c2nc(NC(=O)C3CC3)sc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B02 compound treatment 0.33 0.00538 0.21 0.343 0.0199 0.42 0.4445 0.9503 1167951 IFLab1_004952 OC(CNC1CCCCC1)COc2ccc(cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B03 compound treatment 0.322 -0.00262 -0.1 0.286 -0.0371 -0.78 -0.6214 -0.7942 1158020 IFLab1_004953 O=C1CCCC2=C1C(c3cccs3)n4ncnc4N2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B04 compound treatment 0.331 0.00638 0.25 0.324 9.38E-4 0.02 0.1911 0.7601 1274024 IFLab1_004954 CCN1C(=O)C2ON(C(C2C1=O)c3ccc(cc3)N(C)C)c4ccc(Cl)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B05 compound treatment 0.293 -0.0316 -1.24 0.316 -0.00706 -0.15 -0.9837 -0.7856 2068090 IFLab1_004955 C(c1cccs1)n2c(nc3ccccc23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B06 compound treatment 0.318 -0.00662 -0.26 0.322 -0.00106 -0.02 -0.1999 -0.7647 2068091 IFLab1_004956 Nn1c(SCC(=O)NC2CCCCC2)nnc1C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B07 compound treatment 0.326 0.00138 0.05 0.328 0.00494 0.1 0.1113 0.9543 1449826 IFLab1_004957 CC1(C)CC(=C(C(c2c[nH]c3ccccc23)c4ccccn4)C(=O)C1)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B08 compound treatment 0.372 0.0474 1.86 0.38 0.0569 1.19 2.1596 0.9767 2068092 IFLab1_004958 Nc1ccccc1c2nnc(SCC(=O)c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B09 compound treatment 0.325 3.75E-4 0.01 0.335 0.0119 0.25 0.1871 0.7475 1569512 IFLab1_004959 COc1ccc(cc1OC)c2nn(cc2C(=O)N3CCCCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B10 compound treatment 0.341 0.0164 0.64 0.328 0.00494 0.1 0.5283 0.8102 1733756 IFLab1_004960 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccccc3F)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B11 compound treatment 0.345 0.0204 0.8 0.343 0.0199 0.42 0.8615 0.9538 2068093 IFLab1_004961 COc1ccc(cc1)c2nnc3sc(nn23)c4ccc(Br)o4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B12 compound treatment 0.337 0.0124 0.49 0.335 0.0119 0.25 0.5207 0.952 2068094 IFLab1_004962 COc1ccc(CCN2C(=O)/C(=C\3/C(=O)N(CC=C)c4ccccc34)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B13 compound treatment 0.327 0.00238 0.09 0.336 0.0129 0.27 0.2575 0.899 1572398 IFLab1_004963 Cc1cccn2cc(nc12)c3cccc(NC(=O)CCC(=O)O)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B14 compound treatment 0.334 0.00938 0.37 0.328 0.00494 0.1 0.3337 0.8717 1395341 IFLab1_004964 COc1ccc(cc1)S(=O)(=O)Nc2ccc3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B15 compound treatment 0.329 0.00438 0.17 0.337 0.0139 0.29 0.3279 0.9683 1573171 IFLab1_004965 CC(NCC(O)COc1ccc(Br)cc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B16 compound treatment 0.327 0.00238 0.09 0.34 0.0169 0.35 0.3167 0.8639 1281253 IFLab1_004966 CC(=O)Oc1ccc(cc1)N(C(=O)C)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B17 compound treatment 0.341 0.0164 0.64 0.33 0.00694 0.15 0.5579 0.8453 1373656 IFLab1_004967 Clc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B18 compound treatment 0.343 0.0184 0.72 0.352 0.0289 0.61 0.9391 0.9961 1353522 IFLab1_004968 CCOC(=O)c1sc(NC(=O)CSc2ccc(C)cc2)nc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B19 compound treatment 0.332 0.00738 0.29 0.333 0.00994 0.21 0.3521 0.9867 1569733 IFLab1_004969 Cc1c(C)c2ccccc2n1CC(O)CNCC3CCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B20 compound treatment 0.338 0.0134 0.53 0.328 0.00494 0.1 0.4449 0.8302 2068095 IFLab1_004970 Cc1nnc(SCc2ccc(cc2)C(=O)c3ccc(F)cc3)nc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B21 compound treatment 0.336 0.0114 0.45 0.329 0.00594 0.12 0.4041 0.8706 2068096 IFLab1_004971 Brc1ccc(cc1)n2cnnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B22 compound treatment 0.331 0.00638 0.25 0.317 -0.00606 -0.13 0.0875 0.3116 1391385 IFLab1_004972 NCC(O)COc1ccc2OCOc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B23 mock treatment 0.325 3.75E-4 0.01 0.321 -0.00206 -0.04 -0.0201 -0.4406 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 B24 positive control 0.079 -0.246 -9.66 0.079 -0.244 -5.11 -10.4403 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C01 compound treatment 0.334 0.00938 0.37 0.328 0.00494 0.1 0.3337 0.8717 1252533 IFLab1_004973 COC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C02 compound treatment 0.315 -0.00962 -0.38 0.319 -0.00406 -0.09 -0.3277 -0.8449 1293687 IFLab1_004974 COc1ccc(cc1OC)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C03 compound treatment 0.316 -0.00862 -0.34 0.335 0.0119 0.25 -0.0632 -0.1499 2068097 IFLab1_004975 NC(=O)CSC1=C(C#N)C(C(C(=O)c2cccs2)C(O)(N1)C(F)(F)F)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C04 compound treatment 0.345 0.0204 0.8 0.332 0.00894 0.19 0.6987 0.8494 1523895 IFLab1_004976 C(Sc1nncc(n1)c2ccccc2)c3cn4cccnc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C05 compound treatment 0.338 0.0134 0.53 0.319 -0.00406 -0.09 0.3117 0.5852 2068098 IFLab1_004977 COC(=O)c1ccccc1NC(=O)CSc2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C06 compound treatment 0.347 0.0224 0.88 0.344 0.0209 0.44 0.9319 0.9482 1393524 IFLab1_004978 Fc1cccc(NCc2cn3cccnc3n2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C07 compound treatment 0.337 0.0124 0.49 0.342 0.0189 0.4 0.6243 0.9948 1541517 IFLab1_004979 CCOC(=O)c1c(NC(=O)CCN2CCOCC2)sc3CC(C)CCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C08 compound treatment 0.354 0.0294 1.15 0.356 0.0329 0.69 1.3041 0.9696 1551454 IFLab1_004980 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2F)SCC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C09 compound treatment 0.34 0.0154 0.6 0.337 0.0139 0.29 0.6337 0.9441 1392911 IFLab1_004981 Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C10 compound treatment 0.34 0.0154 0.6 0.345 0.0219 0.46 0.7521 0.9908 1174704 IFLab1_004982 CC1(C)CC(=O)c2cc(C#N)c(SCC(=O)N3CCc4ccccc34)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C11 compound treatment 0.337 0.0124 0.49 0.331 0.00794 0.17 0.4615 0.8976 1400707 IFLab1_004983 Cc1ccc(C)n1n2cnc3scc(c4cccs4)c3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C12 compound treatment 0.334 0.00938 0.37 0.333 0.00994 0.21 0.4077 0.9633 1428542 IFLab1_004984 Cc1ccc(cc1)C2CC(=O)Nc3sc(C(=O)N)c(N)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C13 compound treatment 0.326 0.00138 0.05 0.335 0.0119 0.25 0.2149 0.8407 1526230 IFLab1_004985 Cc1ccc(cc1C)S(=O)(=O)NC(Cc2ccccc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C14 compound treatment 0.329 0.00438 0.17 0.34 0.0169 0.35 0.3723 0.9449 1156965 IFLab1_004986 CCOC(=O)c1sc2nc(cc(c3ccc(OC)cc3)c2c1N)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C15 compound treatment 0.333 0.00838 0.33 0.334 0.0109 0.23 0.3947 0.9842 2068099 IFLab1_004987 Cc1sc2ncnc(SCC(=O)N3CCOCC3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C16 compound treatment 0.341 0.0164 0.64 0.337 0.0139 0.29 0.6615 0.9359 1205072 IFLab1_004988 CCC(=O)Oc1ccc2cc(c3nc4ccccc4n3C)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C17 compound treatment 0.325 3.75E-4 0.01 0.331 0.00794 0.17 0.1279 0.7669 2068100 IFLab1_004989 CCOc1ncnc2sc(cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C18 compound treatment 0.337 0.0124 0.49 0.328 0.00494 0.1 0.4171 0.8386 1517794 IFLab1_004990 CCN(CC)C(=O)c1c2CCCCc2nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C19 compound treatment 0.337 0.0124 0.49 0.336 0.0129 0.27 0.5355 0.9617 1419018 IFLab1_004991 C1Oc2ccc(Oc3nncc4ccccc34)cc2O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C20 compound treatment 0.337 0.0124 0.49 0.321 -0.00206 -0.04 0.3135 0.6419 1458982 IFLab1_004992 CCCCN1C(=O)C2ON(C(C2C1=O)c3cccs3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C21 compound treatment 0.333 0.00838 0.33 0.335 0.0119 0.25 0.4095 0.9907 2068101 IFLab1_004993 O=C(CSc1nnc2ccccn12)Nc3sc4CCCc4c3C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C22 compound treatment 0.33 0.00538 0.21 0.34 0.0169 0.35 0.4001 0.9695 1645696 IFLab1_004994 OC(=O)c1ccc(CN2C(=O)CSC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C23 mock treatment 0.321 -0.00362 -0.14 0.319 -0.00406 -0.09 -0.1609 -0.9695 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 C24 positive control 0.08 -0.245 -9.62 0.079 -0.244 -5.11 -10.4125 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D01 compound treatment 0.342 0.0174 0.68 0.332 0.00894 0.19 0.6153 0.8687 2068102 IFLab1_004995 CC(=O)Nc1nc(cs1)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D02 compound treatment 0.322 -0.00262 -0.1 0.322 -0.00106 -0.02 -0.0887 -0.8402 1181293 IFLab1_004996 CCN1CCN(CC(O)COc2ccc(cc2)C(=O)OC)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D03 compound treatment 0.333 0.00838 0.33 0.332 0.00894 0.19 0.3651 0.9641 1422173 IFLab1_004997 COc1ccc(cc1)c2nc3ccccc3n2C(=O)c4ccccc4C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D04 compound treatment 0.338 0.0134 0.53 0.329 0.00594 0.12 0.4597 0.8508 1468196 IFLab1_004998 CCOc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D05 compound treatment 0.346 0.0214 0.84 0.344 0.0209 0.44 0.9041 0.9539 1242970 IFLab1_004999 Cc1ccccc1OCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D06 compound treatment 0.349 0.0244 0.96 0.351 0.0279 0.58 1.0911 0.9719 2068103 IFLab1_005000 FC(F)(F)c1ccccc1NC(=O)CSc2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D07 compound treatment 0.339 0.0144 0.57 0.332 0.00894 0.19 0.5319 0.8934 1519864 IFLab1_005001 COc1ccc(cc1OC)C(Nc2ccccn2)c3c(C)[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D08 compound treatment 0.343 0.0184 0.72 0.337 0.0139 0.29 0.7171 0.9204 2068104 IFLab1_005002 CC(C)(C)C1=N/C(=C\c2ccccc2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D09 compound treatment 0.349 0.0244 0.96 0.329 0.00594 0.12 0.7655 0.7922 2068105 IFLab1_005003 COc1ccc(cc1)c2nn(cc2/C=C\C(=O)N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D10 compound treatment 0.356 0.0314 1.23 0.372 0.0489 1.02 1.5964 0.9957 1480863 IFLab1_005004 COc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D11 compound treatment 0.346 0.0214 0.84 0.337 0.0139 0.29 0.8005 0.8999 2068106 IFLab1_005005 OC(=O)CSc1nnc(c2ccco2)n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D12 compound treatment 0.341 0.0164 0.64 0.334 0.0109 0.23 0.6171 0.9031 1604864 IFLab1_005006 Cn1c(SCC(=O)NCc2cccnc2)nnc1c3sc4ccccc4c3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D13 compound treatment 0.341 0.0164 0.64 0.332 0.00894 0.19 0.5875 0.8763 1547076 IFLab1_005007 Cc1ccc(cc1)C2SCCN2S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D14 compound treatment 0.333 0.00838 0.33 0.341 0.0179 0.38 0.4983 0.9979 1164761 IFLab1_005008 Cc1ccc(c(C)c1)S(=O)(=O)Nc2ccc(O)c(c2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D15 compound treatment 0.323 -0.00162 -0.06 0.333 0.00994 0.21 0.1019 0.4683 1375016 IFLab1_005009 CN(CC(O)COc1ccc(Br)cc1)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D16 compound treatment 0.338 0.0134 0.53 0.335 0.0119 0.25 0.5485 0.9421 1437364 IFLab1_005010 CCCC(=O)Oc1ccc(cc1)N(C(=O)CCC)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D17 compound treatment 0.337 0.0124 0.49 0.339 0.0159 0.33 0.5799 0.983 1468627 IFLab1_005011 CS(=O)(=O)N1CCN(CC1)c2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D18 compound treatment 0.34 0.0154 0.6 0.341 0.0179 0.38 0.6929 0.9737 1490534 IFLab1_005012 Cc1ccc(SCC(=O)Nc2ccc(I)cn2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D19 compound treatment 0.339 0.0144 0.57 0.331 0.00794 0.17 0.5171 0.8778 1164764 IFLab1_005013 Cc1c(C)c2ccccc2n1CC(O)CN3CCN(CCO)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D20 compound treatment 0.343 0.0184 0.72 0.341 0.0179 0.38 0.7763 0.9535 1588258 IFLab1_005014 COc1ccc(CCNc2nc3ccccc3s2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D21 compound treatment 0.317 -0.00762 -0.3 0.325 0.00194 0.04 -0.1833 -0.606 1415637 IFLab1_005015 CCOC(=O)c1ccc(NC(=O)C2(CCC3(C)C(=O)C2)C3(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D22 compound treatment 0.339 0.0144 0.57 0.335 0.0119 0.25 0.5763 0.9326 2068107 IFLab1_005016 COc1ccc(CCNC(CC(=O)Nc2ccccc2)C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D23 mock treatment 0.321 -0.00362 -0.14 0.324 9.38E-4 0.02 -0.0869 -0.6041 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 D24 positive control 0.081 -0.244 -9.58 0.08 -0.243 -5.09 -10.3699 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E01 compound treatment 0.339 0.0144 0.57 0.351 0.0279 0.58 0.813 0.9999 1645465 IFLab1_005017 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E02 compound treatment 0.308 -0.0166 -0.65 0.327 0.00394 0.08 -0.4039 -0.6131 2068108 IFLab1_005018 COc1ccc(OC)c(/C=N/c2sc3CCCc3c2C#N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E03 compound treatment 0.324 -6.25E-4 -0.02 0.324 9.38E-4 0.02 -0.0035 -0.1114 1176253 IFLab1_005019 CCOC(=O)C1=C(NC(=O)C(C)(C#N)C21CCCCC2)SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E04 compound treatment 0.333 0.00838 0.33 0.32 -0.00306 -0.06 0.1875 0.559 2068109 IFLab1_005020 C(Sc1ncn[nH]1)c2cn3cccnc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E05 compound treatment 0.335 0.0104 0.41 0.324 9.38E-4 0.02 0.3023 0.7403 2068110 IFLab1_005021 [O-][n+]1ccc(cc1)C(=O)NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E06 compound treatment 0.339 0.0144 0.57 0.336 0.0129 0.27 0.5911 0.9432 2068111 IFLab1_005022 FC(F)(F)c1cccc(NCc2cn3cccnc3n2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E07 compound treatment 0.344 0.0194 0.76 0.343 0.0199 0.42 0.8337 0.9598 2068112 IFLab1_005023 O=C(CSc1ncnc2sc(cc12)c3ccccc3)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E08 compound treatment 0.345 0.0204 0.8 0.364 0.0409 0.86 1.1722 0.9994 1645072 IFLab1_005024 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2F)SCC(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E09 compound treatment 0.348 0.0234 0.92 0.346 0.0229 0.48 0.9893 0.9541 1256364 IFLab1_005025 COCCn1c(C)cc(C(=O)CSc2ccc(Cl)cc2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E10 compound treatment 0.354 0.0294 1.15 0.347 0.0239 0.5 1.1709 0.9301 1337342 IFLab1_005026 Fc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E11 compound treatment 0.343 0.0184 0.72 0.343 0.0199 0.42 0.8059 0.966 2068113 IFLab1_005027 O=C(CSc1nnc2sc3ccccc3n12)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E12 compound treatment 0.342 0.0174 0.68 0.332 0.00894 0.19 0.6153 0.8687 1434667 IFLab1_005028 COc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E13 compound treatment 0.344 0.0194 0.76 0.338 0.0149 0.31 0.7597 0.9226 2068114 IFLab1_005029 COC(=O)c1cccc(Oc2ncnc3sc(C)c(C)c23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E14 compound treatment 0.358 0.0334 1.31 0.357 0.0339 0.71 1.4301 0.9584 1848330 IFLab1_005030 COc1ccc(cc1)C(=O)CSc2nc3CCCc3cc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E15 compound treatment 0.343 0.0184 0.72 0.335 0.0119 0.25 0.6875 0.8994 2068115 IFLab1_005031 CCN(CC)c1nnc(Cl)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E16 compound treatment 0.336 0.0114 0.45 0.338 0.0149 0.31 0.5373 0.9847 1353147 IFLab1_005032 COc1ccccc1C(=O)NC2CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E17 compound treatment 0.337 0.0124 0.49 0.343 0.0199 0.42 0.6391 0.9971 2068116 IFLab1_005033 O=C(CSc1nnc2sc3ccccc3n12)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E18 compound treatment 0.293 -0.0316 -1.24 0.299 -0.0241 -0.5 -1.2353 -0.9208 2068117 IFLab1_005034 COc1ccc(NC2=CC(=O)C=CC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E19 compound treatment 0.332 0.00738 0.29 0.334 0.0109 0.23 0.3669 0.9931 1213918 IFLab1_005035 CC1CCN(CC1)c2nncc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E20 compound treatment 0.335 0.0104 0.41 0.335 0.0119 0.25 0.4651 0.9723 1546809 IFLab1_005036 CC(C)N1C(=O)C2ON(C(C2C1=O)c3cccs3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E21 compound treatment 0.341 0.0164 0.64 0.338 0.0149 0.31 0.6763 0.9449 1630387 IFLab1_005037 OC(=O)CCCC(=O)Nc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E22 compound treatment 0.337 0.0124 0.49 0.328 0.00494 0.1 0.4171 0.8386 1712984 IFLab1_005038 Cc1nc(SC(C(=O)O)c2ccccc2)cc(n1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E23 mock treatment 0.319 -0.00562 -0.22 0.318 -0.00506 -0.11 -0.2313 -0.9432 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 E24 positive control 0.082 -0.243 -9.54 0.081 -0.242 -5.07 -10.3273 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F01 compound treatment 0.331 0.00638 0.25 0.33 0.00694 0.15 0.2799 0.9663 1218828 IFLab1_005039 CCC(=O)Nc1nc(cs1)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F02 compound treatment 0.32 -0.00462 -0.18 0.317 -0.00606 -0.13 -0.2183 -0.9845 1676002 IFLab1_005040 COC(=O)c1ccc(OCC(O)CN2CCC(Cc3ccccc3)CC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F03 compound treatment 0.333 0.00838 0.33 0.331 0.00794 0.17 0.3503 0.9498 1347641 IFLab1_005041 OCCCc1nc2ccccc2n1Cc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F04 compound treatment 0.339 0.0144 0.57 0.32 -0.00306 -0.06 0.3543 0.6229 1653668 IFLab1_005042 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cnc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F05 compound treatment 0.325 3.75E-4 0.01 0.323 -6.25E-5 0.0 0.0095 0.6419 1266158 IFLab1_005043 COc1ccccc1OCc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F06 compound treatment 0.338 0.0134 0.53 0.341 0.0179 0.38 0.6373 0.9863 2068118 IFLab1_005044 Cc1nnc2SCC(=Nn12)Nc3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F07 compound treatment 0.34 0.0154 0.6 0.345 0.0219 0.46 0.7521 0.9908 1259496 IFLab1_005045 Cc1[nH]c2ccccc2c1C(N3CCC(CC3)C(=O)N)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F08 compound treatment 0.339 0.0144 0.57 0.331 0.00794 0.17 0.5171 0.8778 2068119 IFLab1_005046 CCC1=N/C(=C\c2ccc(Br)cc2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F09 compound treatment 0.335 0.0104 0.41 0.34 0.0169 0.35 0.5391 0.9975 2068120 IFLab1_005047 CC(=C)Cn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F10 compound treatment 0.344 0.0194 0.76 0.332 0.00894 0.19 0.6709 0.8553 2068121 IFLab1_005048 Cc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F11 compound treatment 0.342 0.0174 0.68 0.346 0.0229 0.48 0.8225 0.9851 2068122 IFLab1_005049 OC(=O)CSc1nnc(c2ccc(Cl)cc2Cl)n1Cc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F12 compound treatment 0.332 0.00738 0.29 0.338 0.0149 0.31 0.4261 0.9993 1443992 IFLab1_005050 O=C(CSc1nnc(o1)c2ccncc2)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F13 compound treatment 0.354 0.0294 1.15 0.348 0.0249 0.52 1.1857 0.9355 2068123 IFLab1_005051 CS(=O)(=O)N1CCSC1c2ccccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F14 compound treatment 0.349 0.0244 0.96 0.35 0.0269 0.56 1.0763 0.968 1714206 IFLab1_005052 OC(=O)c1cc(NS(=O)(=O)c2ccc3ccccc3c2)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F15 compound treatment 0.34 0.0154 0.6 0.342 0.0189 0.4 0.7077 0.979 1277792 IFLab1_005053 C[N+]1(CC(O)COc2ccc(Br)cc2)CCCCC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F16 compound treatment 0.328 0.00338 0.13 0.316 -0.00706 -0.15 -0.0107 -0.0537 1396458 IFLab1_005054 Cc1cc(C)c(cc1C)S(=O)(=O)Nc2cc(SCC(=O)O)c(O)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F17 compound treatment 0.342 0.0174 0.68 0.343 0.0199 0.42 0.7781 0.972 1482477 IFLab1_005055 O=S(=O)(N1CCN(CC1)c2ccccn2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F18 compound treatment 0.345 0.0204 0.8 0.354 0.0309 0.65 1.0243 0.9944 1606813 IFLab1_005056 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccc(cc3)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F19 compound treatment 0.336 0.0114 0.45 0.328 0.00494 0.1 0.3893 0.8481 2068124 IFLab1_005057 CN(C)S(=O)(=O)n1c(C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F20 compound treatment 0.362 0.0374 1.47 0.365 0.0419 0.88 1.6597 0.9696 1446334 IFLab1_005058 CCCCN1C(=O)C2ON(C(C2C1=O)c3cc(Br)ccc3O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F21 compound treatment 0.325 3.75E-4 0.01 0.337 0.0139 0.29 0.2167 0.7419 2068125 IFLab1_005059 Cc1nc(cs1)/C(=N\O)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F22 compound treatment 0.334 0.00938 0.37 0.337 0.0139 0.29 0.4669 0.9933 2068126 IFLab1_005060 CCc1ccc(NC(=O)CC(NCC2CCCO2)C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F23 mock treatment 0.327 0.00238 0.09 0.323 -6.25E-5 0.0 0.0651 0.6971 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 F24 positive control 0.082 -0.243 -9.54 0.081 -0.242 -5.07 -10.3273 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G01 compound treatment 0.336 0.0114 0.45 0.328 0.00494 0.1 0.3893 0.8481 1394739 IFLab1_005061 NC(=O)c1sc2nc3CCCC(=O)c3cc2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G02 compound treatment 0.318 -0.00662 -0.26 0.323 -6.25E-5 0.0 -0.1851 -0.7106 1739828 IFLab1_005062 Oc1ccccc1NC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G03 compound treatment 0.354 0.0294 1.15 0.352 0.0289 0.61 1.2449 0.9546 1309366 IFLab1_005063 Cc1nc2sc(C(=O)N)c(N)c2c(c3ccccc3)c1C(=O)Nc4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G04 compound treatment 0.348 0.0234 0.92 0.355 0.0319 0.67 1.1225 0.9878 2068127 IFLab1_005064 C(Oc1ccccc1)c2cn3cccnc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G05 compound treatment 0.311 -0.0136 -0.54 0.311 -0.0121 -0.25 -0.5573 -0.9411 1738161 IFLab1_005065 COc1ccccc1NC(=O)c2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G06 compound treatment 0.331 0.00638 0.25 0.33 0.00694 0.15 0.2799 0.9663 1125229 IFLab1_005066 Clc1ccc(cc1)C2=CC(c3ccco3)n4ncnc4N2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G07 compound treatment 0.33 0.00538 0.21 0.335 0.0119 0.25 0.3261 0.9965 1480927 IFLab1_005067 OC(=O)C(Cc1ccccc1)NC(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G08 compound treatment 0.36 0.0354 1.39 0.337 0.0139 0.29 1.1897 0.8372 1631224 IFLab1_005068 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G09 compound treatment 0.322 -0.00262 -0.1 0.327 0.00394 0.08 -0.0147 -0.1114 1258870 IFLab1_005069 O=C(CCN1CCCC1)Nc2ccc3OCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G10 compound treatment 0.358 0.0334 1.31 0.347 0.0239 0.5 1.2821 0.9128 1121089 IFLab1_005070 Fc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(F)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G11 compound treatment 0.342 0.0174 0.68 0.352 0.0289 0.61 0.9113 0.9982 2068128 IFLab1_005071 S=c1[nH]cnc2sc(cc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G12 compound treatment 0.347 0.0224 0.88 0.349 0.0259 0.54 1.0059 0.9731 1443171 IFLab1_005072 Cc1ccc(NC(=O)CSc2nc3CC(C)(C)CC(=O)c3cc2C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G13 compound treatment 0.355 0.0304 1.19 0.334 0.0109 0.23 1.0063 0.8276 1399296 IFLab1_005073 COC(=O)c1ccc(Oc2ncnc3sc(C)c(C)c23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G14 compound treatment 0.351 0.0264 1.04 0.341 0.0179 0.38 0.9987 0.9056 1308667 IFLab1_005074 NC(=O)c1sc2nc3CCCCc3cc2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G15 compound treatment 0.339 0.0144 0.57 0.312 -0.0111 -0.23 0.236 0.3863 2068129 IFLab1_005075 Cc1ccc(C)n1c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G16 compound treatment 0.345 0.0204 0.8 0.336 0.0129 0.27 0.7579 0.8963 1462613 IFLab1_005076 COc1ccc(NC2CS(=O)(=O)CC2NCc3ccccc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G17 compound treatment 0.339 0.0144 0.57 0.338 0.0149 0.31 0.6207 0.961 1717975 IFLab1_005077 Cc1sc2ncnc(NCCc3ccc4OCCOc4c3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G18 compound treatment 0.329 0.00438 0.17 0.323 -6.25E-5 0.0 0.1207 0.7017 1468470 IFLab1_005078 Nc1nc(NS(=O)(=O)c2ccccc2)ns1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G19 compound treatment 0.337 0.0124 0.49 0.322 -0.00106 -0.02 0.3283 0.6741 2068130 IFLab1_005079 COc1cc(cc(OC)c1OC)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G20 compound treatment 0.339 0.0144 0.57 0.337 0.0139 0.29 0.6059 0.9526 2068131 IFLab1_005080 CNC(=O)CC1Sc2ccc(cc2NC1=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G21 compound treatment 0.317 -0.00762 -0.3 0.327 0.00394 0.08 -0.1537 -0.4944 2068132 IFLab1_005081 Cc1sc(/N=C\c2ccccc2Cl)c(C#N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G22 compound treatment 0.507 0.182 7.17 0.51 0.187 3.91 7.8365 0.9594 1338036 IFLab1_005082 OC(=O)CSC(=S)Nc1cccnc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G23 mock treatment 0.317 -0.00762 -0.3 0.319 -0.00406 -0.09 -0.2721 -0.8732 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 G24 positive control 0.082 -0.243 -9.54 0.081 -0.242 -5.07 -10.3273 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H01 compound treatment 0.355 0.0304 1.19 0.354 0.0309 0.65 1.3023 0.9586 1428215 IFLab1_005083 CC(=O)Nc1nc(COc2ccc3ccccc3c2)cs1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H02 compound treatment 0.32 -0.00462 -0.18 0.324 9.38E-4 0.02 -0.1147 -0.6272 1279006 IFLab1_005084 COC(=O)c1ccc(OCC(O)CNC(C)(C)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H03 compound treatment 0.333 0.00838 0.33 0.322 -0.00106 -0.02 0.2171 0.6579 1338644 IFLab1_005085 C=CCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H04 compound treatment 0.308 -0.0166 -0.65 0.317 -0.00606 -0.13 -0.5519 -0.8289 1160276 IFLab1_005086 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H05 compound treatment 0.327 0.00238 0.09 0.318 -0.00506 -0.11 -0.0089 -0.0629 1191645 IFLab1_005087 COc1ccc(cc1)C(=O)c2nccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H06 compound treatment 0.36 0.0354 1.39 0.358 0.0349 0.73 1.5005 0.9549 2068133 IFLab1_005088 Clc1ccc(NC2=Nn3cnnc3SC2)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H07 compound treatment 0.35 0.0254 1.0 0.34 0.0169 0.35 0.9561 0.903 1557422 IFLab1_005089 COc1ccc(cc1)C(N2CCCC2)c3c(C)[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H08 compound treatment 0.344 0.0194 0.76 0.332 0.00894 0.19 0.6709 0.8553 2068134 IFLab1_005090 CCC1=N/C(=C\c2ccc(C)cc2)/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H09 compound treatment 0.351 0.0264 1.04 0.335 0.0119 0.25 0.9099 0.853 2068135 IFLab1_005091 Brc1ccc(cc1)c2nnc3sc(nn23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H10 compound treatment 0.364 0.0394 1.55 0.363 0.0399 0.84 1.6857 0.9581 2068136 IFLab1_005092 Cc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H11 compound treatment 0.351 0.0264 1.04 0.32 -0.00306 -0.06 0.688 0.6621 2068137 IFLab1_005093 Cc1cccc(Cn2cnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H12 compound treatment 0.345 0.0204 0.8 0.335 0.0119 0.25 0.7431 0.8855 1261610 IFLab1_005094 NS(=O)(=O)c1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H13 compound treatment 0.351 0.0264 1.04 0.338 0.0149 0.31 0.9543 0.8811 1525872 IFLab1_005095 CS(=O)(=O)N1CCSC1c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H14 compound treatment 0.36 0.0354 1.39 0.345 0.0219 0.46 1.3081 0.8931 1727653 IFLab1_005096 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(c2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H15 compound treatment 0.347 0.0224 0.88 0.329 0.00594 0.12 0.7099 0.799 2068138 IFLab1_005097 CCn1c(SCC(=O)c2ccccc2)nnc1c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H16 compound treatment 0.343 0.0184 0.72 0.318 -0.00506 -0.11 0.436 0.597 1719595 IFLab1_005098 Cc1cccc(NS(=O)(=O)c2cccs2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H17 compound treatment 0.342 0.0174 0.68 0.339 0.0159 0.33 0.7189 0.9456 1683592 IFLab1_005099 O=C1OCCC1Sc2nc3sc4CCCc4c3c(=O)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H18 compound treatment 0.37 0.0454 1.78 0.366 0.0429 0.9 1.8969 0.9496 1873822 IFLab1_005100 CNC1=C(C(=O)c2ccccc2C1=O)n3nnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H19 compound treatment 0.334 0.00938 0.37 0.335 0.0119 0.25 0.4373 0.982 2068139 IFLab1_005101 CN(C)S(=O)(=O)n1nc(C)c(Br)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H20 compound treatment 0.343 0.0184 0.72 0.336 0.0129 0.27 0.7023 0.9103 2068140 IFLab1_005102 Cc1ccc(NC(=O)CC2SC(=N)NC2=O)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H21 compound treatment 0.317 -0.00762 -0.3 0.324 9.38E-4 0.02 -0.1981 -0.6594 1234567 IFLab1_005103 CCOC(=O)N1CCN(CC(O)COc2ccc(cc2)c3ccccc3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H22 compound treatment 0.336 0.0114 0.45 0.327 0.00394 0.08 0.3745 0.8235 2068141 IFLab1_005104 CCc1ccccc1NC(=O)CC(NCC2CCCO2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H23 mock treatment 0.32 -0.00462 -0.18 0.323 -6.25E-5 0.0 -0.1295 -0.7122 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 H24 positive control 0.084 -0.241 -9.46 0.082 -0.241 -5.04 -10.2569 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I01 compound treatment 0.345 0.0204 0.8 0.35 0.0269 0.56 0.9651 0.9852 1217244 IFLab1_005105 Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I02 compound treatment 0.329 0.00438 0.17 0.335 0.0119 0.25 0.2983 0.9834 1614490 IFLab1_005106 COc1ccc(cc1)S(=O)(=O)NCc2ccccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I03 compound treatment 0.341 0.0164 0.64 0.342 0.0189 0.4 0.7355 0.9728 1339718 IFLab1_005107 COC(=O)c1sc2nc3CCCc3c(c4ccc(Cl)cc4)c2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I04 compound treatment 0.378 0.0534 2.1 0.384 0.0609 1.28 2.3856 0.9715 2068142 IFLab1_005108 Cc1ccc(OCc2cn3cccnc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I05 compound treatment 0.336 0.0114 0.45 0.342 0.0189 0.4 0.5965 0.9982 1309285 IFLab1_005109 COc1cccc(NC(=O)c2ccncc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I06 compound treatment 0.339 0.0144 0.57 0.338 0.0149 0.31 0.6207 0.961 1485320 IFLab1_005110 O=C1OCCC1Sc2nc3ccccc3c(=O)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I07 compound treatment 0.342 0.0174 0.68 0.347 0.0239 0.5 0.8373 0.9884 1583959 IFLab1_005111 CC1CCN(CC1)C(=O)CSc2nnc3sc4ccccc4n23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I08 compound treatment 0.354 0.0294 1.15 0.376 0.0529 1.11 1.6 0.9998 1227098 IFLab1_005112 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I09 compound treatment 0.351 0.0264 1.04 0.338 0.0149 0.31 0.9543 0.8811 2068143 IFLab1_005113 O=C(CSc1nnc2sc3ccccc3n12)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I10 compound treatment 0.358 0.0334 1.31 0.359 0.0359 0.75 1.4597 0.9651 1167233 IFLab1_005114 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)N(c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I11 compound treatment 0.356 0.0314 1.23 0.345 0.0219 0.46 1.1969 0.9093 2068144 IFLab1_005115 Cc1nc(Cl)c2cc(sc2n1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I12 compound treatment 0.354 0.0294 1.15 0.319 -0.00406 -0.09 0.7566 0.6533 2068145 IFLab1_005116 CCSc1nc2CCCC(=O)c2cc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I13 compound treatment 0.352 0.0274 1.08 0.337 0.0139 0.29 0.9673 0.8674 1322641 IFLab1_005117 Cc1nc(NCc2ccco2)c3c4CCCc4sc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I14 compound treatment 0.338 0.0134 0.53 0.337 0.0139 0.29 0.5781 0.9613 1292254 IFLab1_005118 OC(=O)CCN1C(=O)C2CC=CCC2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I15 compound treatment 0.338 0.0134 0.53 0.338 0.0149 0.31 0.5929 0.9691 2068146 IFLab1_005119 O=C(CSc1nnc2sc3ccccc3n12)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I16 compound treatment 0.331 0.00638 0.25 0.337 0.0139 0.29 0.3835 0.9972 1167564 IFLab1_005120 COc1cccc(c1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I17 compound treatment 0.348 0.0234 0.92 0.319 -0.00406 -0.09 0.5898 0.639 1709494 IFLab1_005121 OC(=O)C(Cc1ccccc1)NS(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I18 compound treatment 0.345 0.0204 0.8 0.338 0.0149 0.31 0.7875 0.9158 1558129 IFLab1_005122 CC1(C)CC(=O)C=C(C1)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I19 compound treatment 0.326 0.00138 0.05 0.338 0.0149 0.31 0.2593 0.8173 2068147 IFLab1_005123 OC(=O)C(Cc1ccccc1)NS(=O)(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I20 compound treatment 0.342 0.0174 0.68 0.34 0.0169 0.35 0.7337 0.9533 1568157 IFLab1_005124 Cc1onc(c1C(=O)NC2CCSC2=O)c3c(F)cccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I21 compound treatment 0.341 0.0164 0.64 0.335 0.0119 0.25 0.6319 0.915 1387264 IFLab1_005125 OC(=O)c1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I22 compound treatment 0.34 0.0154 0.6 0.35 0.0269 0.56 0.8261 0.9994 1382446 IFLab1_005126 COC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I23 mock treatment 0.33 0.00538 0.21 0.324 9.38E-4 0.02 0.1633 0.7694 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 I24 positive control 0.085 -0.24 -9.42 0.083 -0.24 -5.02 -10.2143 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J01 compound treatment 0.333 0.00838 0.33 0.332 0.00894 0.19 0.3651 0.9641 1461808 IFLab1_005127 CC(C)(C)C(=O)Nc1nc(COc2ccccc2)cs1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J02 compound treatment 0.321 -0.00362 -0.14 0.318 -0.00506 -0.11 -0.1757 -0.9893 1562921 IFLab1_005128 COC(=O)c1ccc(OCC(O)CN2C(C)CCCC2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J03 compound treatment 0.318 -0.00662 -0.26 0.324 9.38E-4 0.02 -0.1703 -0.652 1570310 IFLab1_005129 CC(C)n1c(nc2ccccc12)c3ccc(cc3)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J04 compound treatment 0.317 -0.00762 -0.3 0.323 -6.25E-5 0.0 -0.2129 -0.7102 1422437 IFLab1_005130 COc1ccc(OC)c(c1)S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J05 compound treatment 0.33 0.00538 0.21 0.33 0.00694 0.15 0.2521 0.9832 1611204 IFLab1_005131 OCc1nc(c2ccccc2)n3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J06 compound treatment 0.317 -0.00762 -0.3 0.319 -0.00406 -0.09 -0.2721 -0.8732 2068148 IFLab1_005132 C(Sc1ccccc1)c2nnc3CCCCCn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J07 compound treatment 0.536 0.211 8.31 0.529 0.206 4.31 8.9239 0.9532 2068149 IFLab1_005133 O=C/1NC(=S)S\C1=C/c2cn(CCC#N)nc2c3cccc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J08 compound treatment 0.324 -6.25E-4 -0.02 0.327 0.00394 0.08 0.0409 0.4755 2068150 IFLab1_005134 CCn1c(SCC=C)nnc1c2nnc(SCC=C)n2CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J09 compound treatment 0.334 0.00938 0.37 0.339 0.0159 0.33 0.4965 0.9988 1657953 IFLab1_005135 Brc1ccc(o1)c2nn3c(Cc4ccccc4)nnc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J10 compound treatment 0.349 0.0244 0.96 0.354 0.0309 0.65 1.1355 0.9818 1610795 IFLab1_005136 CCOC(=O)c1c(C)n(CC)c2ccc(OC(=O)c3ccco3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J11 compound treatment 0.347 0.0224 0.88 0.342 0.0189 0.4 0.9023 0.9351 1654477 IFLab1_005137 COCc1nc2ccccc2n1Cc3ccccc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J12 compound treatment 0.342 0.0174 0.68 0.341 0.0179 0.38 0.7485 0.9602 2068151 IFLab1_005138 CC(C)C(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J13 compound treatment 0.345 0.0204 0.8 0.34 0.0169 0.35 0.8171 0.9327 1597313 IFLab1_005139 CS(=O)(=O)N1CCSC1c2cccc(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J14 compound treatment 0.349 0.0244 0.96 0.344 0.0209 0.44 0.9875 0.9371 1188701 IFLab1_005140 OC(=O)c1cc(NS(=O)(=O)c2ccc(Br)cc2)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J15 compound treatment 0.323 -0.00162 -0.06 0.331 0.00794 0.17 0.0723 0.4061 1570777 IFLab1_005141 CCCS(=O)(=O)N1CCN(CC1)c2ccc(OC)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J16 compound treatment 0.34 0.0154 0.6 0.341 0.0179 0.38 0.6929 0.9737 2068152 IFLab1_005142 Oc1ccc(NS(=O)(=O)c2cccs2)cc1Sc3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J17 compound treatment 0.345 0.0204 0.8 0.33 0.00694 0.15 0.6691 0.8219 1270070 IFLab1_005143 OC(=O)C(CSc1ncccn1)CSc2ncccn2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J18 compound treatment 0.371 0.0464 1.82 0.372 0.0489 1.02 2.0135 0.9628 2068153 IFLab1_005144 CC(C)(C)NC1=C(C(=O)c2ccccc2C1=O)n3nnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J19 compound treatment 0.341 0.0164 0.64 0.336 0.0129 0.27 0.6467 0.9259 1203811 IFLab1_005145 O=S(=O)(N1CCOCC1)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J20 compound treatment 0.349 0.0244 0.96 0.34 0.0169 0.35 0.9283 0.9085 1711842 IFLab1_005146 CCCCN1C(=O)C2ON(C(C2C1=O)c3ccco3)c4ccccc4C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J21 compound treatment 0.35 0.0254 1.0 0.34 0.0169 0.35 0.9561 0.903 1201405 IFLab1_005147 CCN1CCN(CC(O)COc2ccc(cc2)c3ccccc3)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J22 compound treatment 0.338 0.0134 0.53 0.337 0.0139 0.29 0.5781 0.9613 2068154 IFLab1_005148 CN(C)C(CC(=O)Nc1ccc(O)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J23 mock treatment 0.326 0.00138 0.05 0.32 -0.00306 -0.06 -0.0071 -0.0845 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 J24 positive control 0.086 -0.239 -9.38 0.084 -0.239 -5.0 -10.1717 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K01 compound treatment 0.355 0.0304 1.19 0.376 0.0529 1.11 1.6278 0.9993 1253348 IFLab1_005149 Clc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K02 compound treatment 0.32 -0.00462 -0.18 0.315 -0.00806 -0.17 -0.2479 -0.9993 1922360 IFLab1_005150 O=C(Oc1ccc2ccccc2c1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K03 compound treatment 0.314 -0.0106 -0.42 0.323 -6.25E-5 0.0 -0.2963 -0.7093 2068155 IFLab1_005151 c1ccc(nc1)c2ccc(nc2)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K04 compound treatment 0.318 -0.00662 -0.26 0.321 -0.00206 -0.04 -0.2147 -0.8132 1299905 IFLab1_005152 COc1ccc(OCc2cn3cccnc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K05 compound treatment 0.317 -0.00762 -0.3 0.315 -0.00806 -0.17 -0.3313 -0.963 1731573 IFLab1_005153 Cn1c(Cc2ccccc2C(=O)O)nc(=O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K06 compound treatment 0.333 0.00838 0.33 0.326 0.00294 0.06 0.2763 0.8249 2068156 IFLab1_005154 ONC(=O)c1ccc(cc1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K07 compound treatment 0.363 0.0384 1.51 0.351 0.0279 0.58 1.4803 0.9148 2068157 IFLab1_005155 Cc1[nH]c2ccccc2c1C(=O)CSc3nc(C)cc(C)c3C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K08 compound treatment 0.354 0.0294 1.15 0.357 0.0339 0.71 1.3189 0.9727 2068158 IFLab1_005156 CC(=O)Nc1ccc(NC=C2C(=O)CC(C)(C)CC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K09 compound treatment 0.337 0.0124 0.49 0.331 0.00794 0.17 0.4615 0.8976 1523217 IFLab1_005157 CC(=O)Nc1ccc(OCc2c(C)noc2C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K10 compound treatment 0.347 0.0224 0.88 0.346 0.0229 0.48 0.9615 0.9594 1447953 IFLab1_005158 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2F)SCC(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K11 compound treatment 0.334 0.00938 0.37 0.34 0.0169 0.35 0.5113 0.9998 1493305 IFLab1_005159 COc1cc(CC=C)ccc1Oc2ncnc3sc(C)c(C)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K12 compound treatment 0.338 0.0134 0.53 0.342 0.0189 0.4 0.6521 0.9903 1190410 IFLab1_005160 NC(=O)CSc1nc2CCCC(=O)c2cc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K13 compound treatment 0.342 0.0174 0.68 0.347 0.0239 0.5 0.8373 0.9884 2068159 IFLab1_005161 Cc1sc2ncnc(SCc3ccco3)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K14 compound treatment 0.34 0.0154 0.6 0.33 0.00694 0.15 0.5301 0.8527 1291239 IFLab1_005162 OC(=O)c1cccc(c1)N2C(=O)C3CC=CCC3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K15 compound treatment 0.335 0.0104 0.41 0.336 0.0129 0.27 0.4799 0.9802 1446192 IFLab1_005163 COc1ccccc1Oc2ncnc3sc(cc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K16 compound treatment 0.348 0.0234 0.92 0.351 0.0279 0.58 1.0633 0.9761 1150502 IFLab1_005164 NC(=O)Cc1nc(cs1)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K17 compound treatment 0.339 0.0144 0.57 0.347 0.0239 0.5 0.7539 0.9982 1725286 IFLab1_005165 C(Nc1nnc(c2cccs2)c3ccccc13)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K18 compound treatment 0.347 0.0224 0.88 0.344 0.0209 0.44 0.9319 0.9482 2068160 IFLab1_005166 Oc1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K19 compound treatment 0.378 0.0534 2.1 0.374 0.0509 1.07 2.2377 0.9507 1568400 IFLab1_005167 COC(=O)c1c(NC(=O)CS(=O)(=O)c2ccccc2)scc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K20 compound treatment 0.312 -0.0126 -0.5 0.341 0.0179 0.38 -0.0856 -0.1375 1538826 IFLab1_005168 CC1CN(CC(C)O1)C(=O)c2cc3c(C)nn(c4ccccc4)c3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K21 compound treatment 0.337 0.0124 0.49 0.339 0.0159 0.33 0.5799 0.983 1058262 IFLab1_005169 O=C(NCc1ccccc1)c2ccc(cc2)C(=O)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K22 compound treatment 0.337 0.0124 0.49 0.341 0.0179 0.38 0.6095 0.9918 1631849 IFLab1_005170 Oc1cccc(c1)N2C(=O)C3CC=CCC3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K23 mock treatment 0.323 -0.00162 -0.06 0.323 -6.25E-5 0.0 -0.0461 -0.7214 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 K24 positive control 0.088 -0.237 -9.3 0.085 -0.238 -4.98 -10.1013 -0.9572 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L01 compound treatment 0.332 0.00738 0.29 0.333 0.00994 0.21 0.3521 0.9867 1672084 IFLab1_005171 CC(C)(C)C(=O)NCC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L02 compound treatment 0.313 -0.0116 -0.46 0.316 -0.00706 -0.15 -0.4277 -0.8904 1326538 IFLab1_005172 COC(=O)c1ccc(OCC(O)CN2CC(C)CC(C)C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L03 compound treatment 0.314 -0.0106 -0.42 0.323 -6.25E-5 0.0 -0.2963 -0.7093 2068161 IFLab1_005173 CC(=C)CSCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L04 compound treatment 0.319 -0.00562 -0.22 0.314 -0.00906 -0.19 -0.2905 -0.9971 2068162 IFLab1_005174 Fc1ccc(Cn2cnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L05 compound treatment 0.321 -0.00362 -0.14 0.315 -0.00806 -0.17 -0.2201 -0.9965 1595692 IFLab1_005175 OC(=O)CCn1c(cc2C(=O)CCCc21)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L06 compound treatment 0.333 0.00838 0.33 0.349 0.0259 0.54 0.6166 0.9713 2068163 IFLab1_005176 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3cc(C)ccc3C)n2N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L07 compound treatment 0.317 -0.00762 -0.3 0.32 -0.00306 -0.06 -0.2573 -0.8393 1438323 IFLab1_005177 Cc1ccc(cc1)c2nn(CCC#N)cc2CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L08 compound treatment 0.368 0.0434 1.71 0.352 0.0289 0.61 1.6341 0.903 1379123 IFLab1_005178 Clc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3cccc4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L09 compound treatment 0.371 0.0464 1.82 0.368 0.0449 0.94 1.9543 0.9526 2068164 IFLab1_005179 Brc1ccccc1c2nnc3sc(nn23)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L10 compound treatment 0.331 0.00638 0.25 0.322 -0.00106 -0.02 0.1615 0.6419 1415537 IFLab1_005180 CN(C)CCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L11 compound treatment 0.327 0.00238 0.09 0.336 0.0129 0.27 0.2575 0.899 1282291 IFLab1_005181 Cc1cccc(Cn2c(CO)nc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L12 compound treatment 0.345 0.0204 0.8 0.329 0.00594 0.12 0.6543 0.8071 2068165 IFLab1_005182 OC(=O)C(Cc1c[nH]c2ccccc12)N3C(=O)C4CC=CCC4C3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L13 compound treatment 0.348 0.0234 0.92 0.338 0.0149 0.31 0.8709 0.8971 2068166 IFLab1_005183 COc1ccc(cc1Br)C2SCCN2S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L14 compound treatment 0.351 0.0264 1.04 0.348 0.0249 0.52 1.1023 0.9495 2068167 IFLab1_005184 Oc1ccc(NS(=O)(=O)c2cccs2)cc1c3c(O)ccc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L15 compound treatment 0.335 0.0104 0.41 0.338 0.0149 0.31 0.5095 0.9914 1298159 IFLab1_005185 CCCS(=O)(=O)N1CCN(CC1)c2cccc(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L16 compound treatment 0.115 -0.21 -8.24 0.11 -0.213 -4.46 -8.9807 -0.9584 2068168 IFLab1_005186 O=C1C=CC(=NS(=O)(=O)c2cccs2)C=C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L17 compound treatment 0.345 0.0204 0.8 0.342 0.0189 0.4 0.8467 0.9473 1504417 IFLab1_005187 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CNCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L18 compound treatment 0.333 0.00838 0.33 0.321 -0.00206 -0.04 0.2023 0.6092 1328135 IFLab1_005188 O=C(C1Cc2ccccc2CN1S(=O)(=O)c3cccs3)N4CCCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L19 compound treatment 0.324 -6.25E-4 -0.02 0.348 0.0249 0.52 0.3516 0.6731 2068169 IFLab1_005189 C/C(=N\O)/c1ccc2c(c1)n(C)c3ccccc32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L20 compound treatment 0.345 0.0204 0.8 0.334 0.0109 0.23 0.7283 0.8742 1508288 IFLab1_005190 O=C1NC(=O)C2C(N(OC21)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L21 compound treatment 0.349 0.0244 0.96 0.357 0.0339 0.71 1.1799 0.9891 1173425 IFLab1_005191 COc1ccc(cc1)N2CCN(CC(O)COc3ccc(cc3)c4ccccc4)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L22 compound treatment 0.342 0.0174 0.68 0.316 -0.00706 -0.15 0.3786 0.5416 2068170 IFLab1_005192 Cc1ccc(NC(=O)CC(NCCC2=CCCCC2)C(=O)O)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L23 mock treatment 0.327 0.00238 0.09 0.324 9.38E-4 0.02 0.0799 0.8374 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 L24 positive control 0.089 -0.236 -9.26 0.086 -0.237 -4.96 -10.0587 -0.9572 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M01 compound treatment 0.326 0.00138 0.05 0.327 0.00394 0.08 0.0965 0.9791 2068171 IFLab1_005193 CC1(C)CC(=O)C(=CNc2ccc(F)c(F)c2)C(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M02 compound treatment 0.316 -0.00862 -0.34 0.315 -0.00806 -0.17 -0.3591 -0.9481 1453382 IFLab1_005194 COc1ccc(OC)c(c1)S(=O)(=O)n2ccnc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M03 compound treatment 0.313 -0.0116 -0.46 0.319 -0.00406 -0.09 -0.3833 -0.8245 2068172 IFLab1_005195 OC(=O)CSc1nnc(c2cccs2)n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M04 compound treatment 0.366 0.0414 1.63 0.385 0.0619 1.3 2.0668 0.9937 1656648 IFLab1_005196 Cc1cc(OCc2cn3cccnc3n2)ccc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M05 compound treatment 0.324 -6.25E-4 -0.02 0.293 -0.0301 -0.63 -0.4622 -0.7342 1134171 IFLab1_005197 COC(=O)c1ccccc1Cc2nc(=O)c3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M06 compound treatment 0.329 0.00438 0.17 0.326 0.00294 0.06 0.1651 0.9038 2068173 IFLab1_005198 ONC(=O)c1ccccc1C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M07 compound treatment 0.333 0.00838 0.33 0.331 0.00794 0.17 0.3503 0.9498 1336083 IFLab1_005199 Cc1cc(N)n(n1)c2ncnc3sc4CCCc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M08 compound treatment 0.367 0.0424 1.67 0.365 0.0419 0.88 1.7987 0.9552 2068174 IFLab1_005200 COc1cc(NC=C2C(=O)CC(C)(C)CC2=O)c(OC)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M09 compound treatment 0.343 0.0184 0.72 0.349 0.0259 0.54 0.8947 0.9901 2068175 IFLab1_005201 CCOC(=O)c1cnn(c1N)c2ccc(Cl)c(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M10 compound treatment 0.351 0.0264 1.04 0.348 0.0249 0.52 1.1023 0.9495 2068176 IFLab1_005202 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M11 compound treatment 0.352 0.0274 1.08 0.34 0.0169 0.35 1.0117 0.8928 1492077 IFLab1_005203 CC1CN(CC(C)O1)S(=O)(=O)c2c(C)c(C)cc(C)c2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M12 compound treatment 0.352 0.0274 1.08 0.362 0.0389 0.81 1.3372 0.9906 1200931 IFLab1_005204 Clc1ccc(CSc2nc3CCCC(=O)c3cc2C#N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M13 compound treatment 0.338 0.0134 0.53 0.341 0.0179 0.38 0.6373 0.9863 1284362 IFLab1_005205 CCOC(=O)c1nn(cc1O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M14 compound treatment 0.348 0.0234 0.92 0.346 0.0229 0.48 0.9893 0.9541 1334392 IFLab1_005206 Cc1oc2ccc(OCc3cccc(F)c3)cc2c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M15 compound treatment 0.342 0.0174 0.68 0.345 0.0219 0.46 0.8077 0.9813 2068177 IFLab1_005207 Cc1sc2ncn(n3cccc3)c(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M16 compound treatment 0.329 0.00438 0.17 0.334 0.0109 0.23 0.2835 0.9901 1013035 IFLab1_005208 O=S(=O)(Nc1ccccc1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M17 compound treatment 0.344 0.0194 0.76 0.348 0.0249 0.52 0.9077 0.983 1517837 IFLab1_005209 Cc1nc2scc(c3cccs3)c2c(=O)n1n4cccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M18 compound treatment 0.348 0.0234 0.92 0.344 0.0209 0.44 0.9597 0.9426 1197592 IFLab1_005210 OC(=O)c1ccccc1SC2CC(=O)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M19 compound treatment 0.336 0.0114 0.45 0.342 0.0189 0.4 0.5965 0.9982 1657419 IFLab1_005211 COc1cc(cc(OC)c1OC)c2nc3sc4CCCCc4c3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M20 compound treatment 0.346 0.0214 0.84 0.341 0.0179 0.38 0.8597 0.934 1188518 IFLab1_005212 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M21 compound treatment 0.353 0.0284 1.12 0.355 0.0319 0.67 1.2615 0.97 2068178 IFLab1_005213 N#Cc1c(/N=C/c2cccs2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M22 compound treatment 0.336 0.0114 0.45 0.341 0.0179 0.38 0.5817 0.9962 2068179 IFLab1_005214 C(Sc1nnc(o1)c2ccncc2)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M23 mock treatment 0.332 0.00738 0.29 0.332 0.00894 0.19 0.3373 0.9775 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 M24 positive control 0.092 -0.233 -9.15 0.088 -0.235 -4.92 -9.9457 -0.9577 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N01 compound treatment 0.326 0.00138 0.05 0.327 0.00394 0.08 0.0965 0.9791 1500866 IFLab1_005215 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)n2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N02 compound treatment 0.314 -0.0106 -0.42 0.313 -0.0101 -0.21 -0.4443 -0.9497 1253630 IFLab1_005216 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)Nc4nccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N03 compound treatment 0.318 -0.00662 -0.26 0.314 -0.00906 -0.19 -0.3183 -0.9878 1287593 IFLab1_005217 Oc1cccc(c1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N04 compound treatment 0.319 -0.00562 -0.22 0.322 -0.00106 -0.02 -0.1721 -0.7743 1370978 IFLab1_005218 CC(O)c1nc2ccccc2n1CCC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N05 compound treatment 0.337 0.0124 0.49 0.34 0.0169 0.35 0.5947 0.9879 1740639 IFLab1_005219 Cc1[nH]c2ccccc2c1Sc3ccccc3N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N06 compound treatment 0.372 0.0474 1.86 0.373 0.0499 1.05 2.0561 0.9627 2068180 IFLab1_005220 COc1ccc(cc1)C2Nn3c(C)nnc3SC2C(=O)c4ccc(Cl)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N07 compound treatment 0.336 0.0114 0.45 0.341 0.0179 0.38 0.5817 0.9962 1304164 IFLab1_005221 CCN(CC)C(=O)c1cn(nc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N08 compound treatment 0.352 0.0274 1.08 0.352 0.0289 0.61 1.1893 0.963 2068181 IFLab1_005222 Cn1c(COc2cccc3cccnc23)nnc1SCC(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N09 compound treatment 0.379 0.0544 2.14 0.409 0.0859 1.8 2.7834 0.9963 2068182 IFLab1_005223 Clc1ccc(cc1)c2nnc3sc(nn23)c4ccc(Br)o4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N10 compound treatment 0.33 0.00538 0.21 0.335 0.0119 0.25 0.3261 0.9965 1264894 IFLab1_005224 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccc(F)cc3)C(=O)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N11 compound treatment 0.353 0.0284 1.12 0.351 0.0279 0.58 1.2023 0.9545 1308561 IFLab1_005225 CC(=O)Nc1cccc(c1)c2cn3c(C)cccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N12 compound treatment 0.351 0.0264 1.04 0.366 0.0429 0.9 1.3686 0.9975 1550936 IFLab1_005226 O=c1oc2ccc(NS(=O)(=O)c3ccccc3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N13 compound treatment 0.349 0.0244 0.96 0.346 0.0229 0.48 1.0171 0.9489 1731231 IFLab1_005227 CC(C)NCC(O)COc1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N14 compound treatment 0.329 0.00438 0.17 0.32 -0.00306 -0.06 0.0763 0.4157 1257153 IFLab1_005228 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cccs3)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N15 compound treatment 0.343 0.0184 0.72 0.344 0.0209 0.44 0.8207 0.9713 2068183 IFLab1_005229 CCn1c(SCC(=O)c2ccccc2)nnc1c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N16 compound treatment 0.343 0.0184 0.72 0.336 0.0129 0.27 0.7023 0.9103 1305541 IFLab1_005230 CN(C(=O)COc1ccccc1)C2(C)CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N17 compound treatment 0.355 0.0304 1.19 0.343 0.0199 0.42 1.1395 0.9007 1720348 IFLab1_005231 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CN4CCN(CCO)CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N18 compound treatment 0.325 3.75E-4 0.01 0.341 0.0179 0.38 0.2758 0.7343 1581419 IFLab1_005232 CC(C)(C)NC(=O)C1Cc2ccccc2CN1S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N19 compound treatment 0.339 0.0144 0.57 0.33 0.00694 0.15 0.5023 0.8608 1309428 IFLab1_005233 OC(CNC1CCCC1)Cn2c3ccccc3c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N20 compound treatment 0.351 0.0264 1.04 0.342 0.0189 0.4 1.0135 0.9129 1180231 IFLab1_005234 CCCCN1C(=O)C2ON(C(C2C1=O)c3ccccc3)c4ccc(Cl)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N21 compound treatment 0.351 0.0264 1.04 0.343 0.0199 0.42 1.0283 0.9199 1341724 IFLab1_005235 OC(COc1ccc(cc1)c2ccccc2)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N22 compound treatment 0.337 0.0124 0.49 0.338 0.0149 0.31 0.5651 0.9771 2068184 IFLab1_005236 Cc1ccc(C)c(NC(=O)CC(NC2CCCCC2)C(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N23 mock treatment 0.33 0.00538 0.21 0.327 0.00394 0.08 0.2077 0.9157 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 N24 positive control 0.092 -0.233 -9.15 0.088 -0.235 -4.92 -9.9457 -0.9577 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O01 compound treatment 0.316 -0.00862 -0.34 0.324 9.38E-4 0.02 -0.2259 -0.6651 2068185 IFLab1_005237 CCOc1ccc(NC=C2C(=O)CC(C)(C)CC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O02 compound treatment 0.311 -0.0136 -0.54 0.308 -0.0151 -0.32 -0.6017 -0.968 2068186 IFLab1_005238 Clc1ccc(cc1)C(=O)COC(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O03 compound treatment 0.313 -0.0116 -0.46 0.309 -0.0141 -0.29 -0.5313 -0.9773 2068187 IFLab1_005239 Cc1cc(C)n(n1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O04 compound treatment 0.323 -0.00162 -0.06 0.313 -0.0101 -0.21 -0.1941 -0.882 1213491 IFLab1_005240 Brc1ccc(OCc2cn3cccnc3n2)c(Br)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O05 compound treatment 0.439 0.114 4.5 0.45 0.127 2.66 5.0582 0.9685 1246967 IFLab1_005241 COc1ccc(cc1)N2C(=O)Cc3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O06 compound treatment 0.316 -0.00862 -0.34 0.314 -0.00906 -0.19 -0.3739 -0.9623 2068188 IFLab1_005242 ONC(=O)c1cccc(c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O07 compound treatment 0.322 -0.00262 -0.1 0.331 0.00794 0.17 0.0445 0.2274 1473061 IFLab1_005243 CCN1CCN(CC1)c2nnc(c3ccccc3)c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O08 compound treatment 0.364 0.0394 1.55 0.368 0.0449 0.94 1.7596 0.9714 2068189 IFLab1_005244 O=C(CSC1=C(C#N)C(CC(=O)N1)c2cccs2)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O09 compound treatment 0.333 0.00838 0.33 0.337 0.0139 0.29 0.4391 0.9982 1692380 IFLab1_005245 O=C(CCN1CCOCC1)Nc2sc3CCCCCc3c2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O10 compound treatment 0.337 0.0124 0.49 0.338 0.0149 0.31 0.5651 0.9771 1138453 IFLab1_005246 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O11 compound treatment 0.323 -0.00162 -0.06 0.332 0.00894 0.19 0.0871 0.4406 1583395 IFLab1_005247 CCC(CO)Nc1nc(C)nc2sc3CCCCc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O12 compound treatment 0.345 0.0204 0.8 0.341 0.0179 0.38 0.8319 0.9403 1562432 IFLab1_005248 COC(=O)CSc1nc2CCCC(=O)c2cc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O13 compound treatment 0.338 0.0134 0.53 0.34 0.0169 0.35 0.6225 0.9816 1570944 IFLab1_005249 CCOC(=O)c1nn(cc1O)c2ccc(OCC)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O14 compound treatment 0.421 0.0964 3.79 0.397 0.0739 1.55 3.7735 0.9219 1568943 IFLab1_005250 CN(C)Cc1c(O)ccc2cc(c3nc4ccccc4o3)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O15 compound treatment 0.342 0.0174 0.68 0.337 0.0139 0.29 0.6893 0.928 1742097 IFLab1_005251 CC1(C)C2CCC1(CS(=O)(=O)Nc3ccc(F)c(Cl)c3)C(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O16 compound treatment 0.345 0.0204 0.8 0.343 0.0199 0.42 0.8615 0.9538 1736528 IFLab1_005252 CN(C)C(=O)c1c2CCCCc2nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O17 compound treatment 0.339 0.0144 0.57 0.341 0.0179 0.38 0.6651 0.9802 2068190 IFLab1_005253 Cc1sc2ncn3nnnc3c2c1c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O18 compound treatment 0.301 -0.0236 -0.93 0.293 -0.0301 -0.63 -1.1017 -0.982 1596620 IFLab1_005254 NC(=O)CC1Nc2ccccc2NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O19 compound treatment 0.333 0.00838 0.33 0.336 0.0129 0.27 0.4243 0.9953 2068191 IFLab1_005255 Cc1sc2ncn3cnnc3c2c1c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O20 compound treatment 0.347 0.0224 0.88 0.343 0.0199 0.42 0.9171 0.9419 1363821 IFLab1_005256 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NCCN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O21 compound treatment 0.342 0.0174 0.68 0.339 0.0159 0.33 0.7189 0.9456 1457538 IFLab1_005257 CC(C)(C)c1ccc(cc1)C(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O22 compound treatment 0.342 0.0174 0.68 0.341 0.0179 0.38 0.7485 0.9602 1553347 IFLab1_005258 CCOC(=O)c1sc(NC(=O)c2cc(=O)c3ccccc3o2)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O23 mock treatment 0.327 0.00238 0.09 0.323 -6.25E-5 0.0 0.0651 0.6971 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 O24 positive control 0.095 -0.23 -9.03 0.091 -0.232 -4.86 -9.8179 -0.9577 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P01 compound treatment 0.336 0.0114 0.45 0.337 0.0139 0.29 0.5225 0.9785 1639695 IFLab1_005259 CC1=C(C(c2ccccc2F)n3ncnc3N1)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P02 compound treatment 0.321 -0.00362 -0.14 0.323 -6.25E-5 0.0 -0.1017 -0.7136 1677121 IFLab1_005260 CCCCN1C(=O)C2ON(C(C2C1=O)c3ccc(OC)cc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P03 compound treatment 0.323 -0.00162 -0.06 0.325 0.00194 0.04 -0.0165 -0.2182 2068192 IFLab1_005261 OC(=O)C1CN(CC=C)C(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P04 compound treatment 0.34 0.0154 0.6 0.343 0.0199 0.42 0.7225 0.9836 1651615 IFLab1_005262 OCc1nc2ccccc2n1CCC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P05 compound treatment 0.398 0.0734 2.88 0.41 0.0869 1.82 3.3264 0.9753 1149352 IFLab1_005263 CC(C)(C)N1COc2c(C1)cc(Cl)c3cccnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P06 compound treatment 0.36 0.0354 1.39 0.362 0.0389 0.81 1.5597 0.9675 2068193 IFLab1_005264 Cc1ccc(NC(=O)CSc2nnc([nH]2)c3ccc(Br)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P07 compound treatment 0.368 0.0434 1.71 0.374 0.0509 1.07 1.9596 0.9744 1327405 IFLab1_005265 O=C(Nc1nccs1)c2cn(nc2c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P08 compound treatment 0.352 0.0274 1.08 0.381 0.0579 1.21 1.6184 0.9982 2068194 IFLab1_005266 OC(=O)CC(Sc1nnc[nH]1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P09 compound treatment 0.36 0.0354 1.39 0.382 0.0589 1.23 1.8556 0.9982 2068195 IFLab1_005267 Brc1ccc(cc1)c2nn3c(nnc3s2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P10 compound treatment 0.363 0.0384 1.51 0.389 0.0659 1.38 2.0426 0.999 1670029 IFLab1_005268 COC(=O)CC1N(CCNC1=O)C(=O)c2sc3ccccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P11 compound treatment 0.364 0.0394 1.55 0.364 0.0409 0.86 1.7005 0.9611 1739671 IFLab1_005269 CC(=O)Nc1cccc(c1)c2cn3cccc(C)c3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P12 compound treatment 0.375 0.0504 1.98 0.381 0.0579 1.21 2.2578 0.9723 1451858 IFLab1_005270 Cc1ccc(c(C)c1)S(=O)(=O)Nc2ccc3oc(=O)sc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P13 compound treatment 0.355 0.0304 1.19 0.368 0.0449 0.94 1.5094 0.993 1280369 IFLab1_005271 CC(C)(C)NCC(O)COc1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P14 compound treatment 0.381 0.0564 2.22 0.401 0.0779 1.63 2.7206 0.9886 1431576 IFLab1_005272 O=C1CCCc2oc3ccc(NS(=O)(=O)c4cccs4)cc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P15 compound treatment 0.367 0.0424 1.67 0.368 0.0449 0.94 1.8431 0.9634 2068196 IFLab1_005273 Clc1cccc(c1)N2CCN(CC2)S(=O)(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P16 compound treatment 0.359 0.0344 1.35 0.35 0.0269 0.56 1.3543 0.9248 1406246 IFLab1_005274 CN(C1CCS(=O)(=O)C1)C(=O)CSc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P17 compound treatment 0.358 0.0334 1.31 0.365 0.0419 0.88 1.5484 0.9809 1689228 IFLab1_005275 Cc1c(C)c2ccccc2n1CC(O)CNC3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P18 compound treatment 0.375 0.0504 1.98 0.35 0.0269 0.56 1.7991 0.8737 1602093 IFLab1_005276 CC1(C)CC(=O)C2=C(C1)Nc3nc(O)nc(O)c3C2c4ccc(Br)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P19 compound treatment 0.359 0.0344 1.35 0.352 0.0289 0.61 1.3839 0.9344 1649149 IFLab1_005277 COC(=O)CCc1nc2c(ccc3ccccc23)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P20 compound treatment 0.356 0.0314 1.23 0.354 0.0309 0.65 1.3301 0.9547 1654002 IFLab1_005278 NCC(O)COCC1COc2ccccc2O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P21 compound treatment 0.353 0.0284 1.12 0.35 0.0269 0.56 1.1875 0.95 2068197 IFLab1_005279 BrCC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P22 compound treatment 0.349 0.0244 0.96 0.349 0.0259 0.54 1.0615 0.9637 2068198 IFLab1_005280 Cc1ccc(NC(=O)CC(NCc2ccco2)C(=O)O)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P23 mock treatment 0.333 0.00838 0.33 0.335 0.0119 0.25 0.4095 0.9907 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1426 P24 positive control 0.099 -0.226 -8.87 0.094 -0.229 -4.79 -9.6623 -0.9582 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A01 compound treatment 0.25 -0.0771 -3.03 0.244 -0.0815 -1.71 -3.3485 -0.963 2068199 IFLab1_005281 [O-]/[N+](=C\c1ccncc1)/c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A02 compound treatment 0.327 -6.25E-5 0.0 0.32 -0.0055 -0.12 -0.0831 -0.722 2068200 IFLab1_005282 O=C(Nc1cccc(c1)c2nc3ccccc3s2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A03 compound treatment 0.33 0.00294 0.12 0.319 -0.0065 -0.14 -0.0145 -0.0813 1985810 IFLab1_005283 C(Sc1nc2ccccc2[nH]1)Sc3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A04 compound treatment 0.347 0.0199 0.78 0.326 5.0E-4 0.01 0.5617 0.7165 2068201 IFLab1_005284 O=C(Nc1nc-2c(Cc3ccccc23)s1)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A05 compound treatment 0.331 0.00394 0.15 0.319 -0.0065 -0.14 0.0133 0.0645 1436032 IFLab1_005285 COc1ccccc1NCC(O)COc2ccc(Cl)cc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A06 compound treatment 0.35 0.0229 0.9 0.345 0.0195 0.41 0.9263 0.9357 2068202 IFLab1_005286 O=C(Nc1ccc(cc1)c2nc3ccccc3[nH]2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A07 compound treatment 0.328 9.38E-4 0.04 0.356 0.0305 0.64 0.4774 0.7467 1590898 IFLab1_005287 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3nccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A08 compound treatment 0.369 0.0419 1.65 0.347 0.0215 0.45 1.4841 0.8683 2068203 IFLab1_005288 NS(=O)(=O)c1ccc(NC(=O)c2ccc(s2)c3nc4ccccc4s3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A09 compound treatment 0.33 0.00294 0.12 0.338 0.0125 0.26 0.2666 0.9325 2068204 IFLab1_005289 Cc1ccc(cc1)C2=CSc3nnc(c4ccccc4Br)n3N2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A10 compound treatment 0.326 -0.00106 -0.04 0.346 0.0205 0.43 0.2738 0.6352 2068205 IFLab1_005290 Oc1c(CN2CCOCC2)ccc3cccnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A11 compound treatment 0.329 0.00194 0.08 0.33 0.0045 0.09 0.1205 0.9945 1873703 IFLab1_005291 CC(=O)Nc1ccc(OCC(O)CN2CCc3ccccc3C2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A12 compound treatment 0.389 0.0619 2.44 0.354 0.0285 0.6 2.1437 0.855 2068206 IFLab1_005292 COc1ccc(NC(=O)CSc2nc3ccccc3nc2O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A13 compound treatment 0.326 -0.00106 -0.04 0.345 0.0195 0.41 0.259 0.6314 2068207 IFLab1_005293 CCOc1cccc2sc(=NC(=O)c3ccc(C#N)cc3)n(CC)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A14 compound treatment 0.31 -0.0171 -0.67 0.32 -0.0055 -0.12 -0.5558 -0.8165 2068208 IFLab1_005294 Cc1ccc2n(CC(O)CNCc3ccccc3)c4C(=O)CCCc4c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A15 compound treatment 0.324 -0.00306 -0.12 0.315 -0.0105 -0.22 -0.2405 -0.9599 2068209 IFLab1_005295 CC(=O)N1CCc2c(C#N)c(NC(=O)/C=C/c3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A16 compound treatment 0.355 0.0279 1.1 0.343 0.0175 0.37 1.0357 0.8944 2068210 IFLab1_005296 FC(F)(F)c1cccc(NC2=NC(=O)CS2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A17 compound treatment 0.323 -0.00406 -0.16 0.323 -0.0025 -0.05 -0.1499 -0.8921 2068211 IFLab1_005297 COC(=O)c1ccc2nc(NC(=O)C3CC3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A18 compound treatment 0.326 -0.00106 -0.04 0.324 -0.0015 -0.03 -0.0517 -0.9901 1511336 IFLab1_005298 CN(C)S(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)N(C)C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A19 compound treatment 0.341 0.0139 0.55 0.346 0.0205 0.43 0.6908 0.9927 2068212 IFLab1_005299 CC(=O)Nc1nc(cs1)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A20 compound treatment 0.329 0.00194 0.08 0.328 0.0025 0.05 0.0909 0.9832 1245578 IFLab1_005300 CC1CN(CC(C)O1)C(=O)c2cccc3C(=O)c4ccccc4-c32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A21 compound treatment 0.339 0.0119 0.47 0.338 0.0125 0.26 0.5169 0.9619 2068213 IFLab1_005301 CC1(C)CC(=O)c2sc(NC(=O)C3=COCCO3)nc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A22 compound treatment 0.317 -0.0101 -0.4 0.32 -0.0055 -0.12 -0.3611 -0.8765 2068214 IFLab1_005302 COCCn1c(COc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A23 mock treatment 0.349 0.0219 0.86 0.317 -0.0085 -0.18 0.4841 0.5497 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 A24 positive control 0.079 -0.248 -9.75 0.079 -0.247 -5.16 -10.5441 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B01 compound treatment 0.339 0.0119 0.47 0.336 0.0105 0.22 0.4873 0.9402 2068215 IFLab1_005303 COC(=O)c1ccsc1NC(=O)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B02 compound treatment 0.316 -0.0111 -0.43 0.317 -0.0085 -0.18 -0.4333 -0.9221 2068216 IFLab1_005304 O=C(Nc1nnc(o1)c2ccccc2)/C=C/c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B03 compound treatment 0.337 0.00994 0.39 0.333 0.0075 0.16 0.3873 0.9197 2068217 IFLab1_005305 NC(=O)c1ccsc1NC(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B04 compound treatment 0.331 0.00394 0.15 0.331 0.0055 0.12 0.1909 0.9893 2068218 IFLab1_005306 O=C(Nc1nnc(o1)c2cccs2)c3ccc4CCCCc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B05 compound treatment 0.319 -0.00806 -0.32 0.326 5.0E-4 0.01 -0.2168 -0.6834 2068219 IFLab1_005307 NC(=O)c1ccsc1NC(=O)C2CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B06 compound treatment 0.317 -0.0101 -0.4 0.319 -0.0065 -0.14 -0.3759 -0.8986 2068220 IFLab1_005308 CCCC(=O)N=c1sc2cc(Cl)ccc2n1CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B07 compound treatment 0.368 0.0409 1.61 0.347 0.0215 0.45 1.4563 0.8714 2068221 IFLab1_005309 CNC(=O)c1ccsc1NC(=O)c2cc3ccccc3cc2OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B08 compound treatment 0.357 0.0299 1.18 0.347 0.0215 0.45 1.1505 0.913 2068222 IFLab1_005310 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B09 compound treatment 0.323 -0.00406 -0.16 0.336 0.0105 0.22 0.0424 0.1562 2068223 IFLab1_005311 COCCn1c(=NC(=O)c2ccccc2)sc3cc(ccc13)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B10 compound treatment 0.331 0.00394 0.15 0.334 0.0085 0.18 0.2352 0.9976 2068224 IFLab1_005312 O=C(Nc1sccc1C#N)c2coc3ccccc3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B11 compound treatment 0.335 0.00794 0.31 0.335 0.0095 0.2 0.3613 0.9763 2068225 IFLab1_005313 CN(C)C(=O)CSc1nnc2cc(C)c3ccccc3n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B12 compound treatment 0.329 0.00194 0.08 0.339 0.0135 0.28 0.2536 0.8668 2068226 IFLab1_005314 CC(C)Oc1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B13 compound treatment 0.334 0.00694 0.27 0.325 -5.0E-4 -0.01 0.1855 0.6795 2068227 IFLab1_005315 CC(C)OC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B14 compound treatment 0.328 9.38E-4 0.04 0.332 0.0065 0.14 0.1222 0.8674 2068228 IFLab1_005316 COc1cc2CCNC(COc3cc(C)cc(C)c3)c2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B15 compound treatment 0.325 -0.00206 -0.08 0.323 -0.0025 -0.05 -0.0943 -0.9775 2068229 IFLab1_005317 CC(=O)Nc1ccc2n(CC=C)c(=NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B16 compound treatment 0.326 -0.00106 -0.04 0.324 -0.0015 -0.03 -0.0517 -0.9901 2068230 IFLab1_005318 NCCSc1c[nH]c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B17 compound treatment 0.335 0.00794 0.31 0.325 -5.0E-4 -0.01 0.2133 0.683 2068231 IFLab1_005319 OC(=O)c1cnccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B18 compound treatment 0.344 0.0169 0.67 0.341 0.0155 0.32 0.7003 0.9453 2068232 IFLab1_005320 COc1ccc(cc1)c2cnnn2c3ccc(N)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B19 compound treatment 0.332 0.00494 0.19 0.328 0.0025 0.05 0.1743 0.8667 2068233 IFLab1_005321 COC(=O)c1ccccc1S(=O)(=O)NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B20 compound treatment 0.357 0.0299 1.18 0.356 0.0305 0.64 1.2836 0.9587 2068234 IFLab1_005322 OC1=C(C(=O)c2cccs2)C(=O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B21 compound treatment 0.338 0.0109 0.43 0.338 0.0125 0.26 0.489 0.9716 2068235 IFLab1_005323 CCCC(=O)Nc1nnc(o1)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B22 compound treatment 0.339 0.0119 0.47 0.344 0.0185 0.39 0.6056 0.9954 2068236 IFLab1_005324 Cc1ccc2n(CC(=O)O)c3nc4ccccc4nc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B23 mock treatment 0.327 -6.25E-5 0.0 0.329 0.0035 0.07 0.0501 0.683 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 B24 positive control 0.078 -0.249 -9.79 0.079 -0.247 -5.16 -10.5719 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C01 compound treatment 0.338 0.0109 0.43 0.34 0.0145 0.3 0.5186 0.9854 2068237 IFLab1_005325 Cc1ccc(NC(=O)CC(NCc2cccnc2)C(=O)O)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C02 compound treatment 0.327 -6.25E-5 0.0 0.322 -0.0035 -0.07 -0.0535 -0.7304 2068238 IFLab1_005326 O=C(Nc1ccccc1c2nc3ccccc3s2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C03 compound treatment 0.33 0.00294 0.12 0.33 0.0045 0.09 0.1483 0.9949 2068239 IFLab1_005327 CCS(=O)c1nc2c(Br)cccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C04 compound treatment 0.342 0.0149 0.59 0.34 0.0145 0.3 0.6299 0.9528 2068240 IFLab1_005328 O=C(N1CCCc2ccccc12)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C05 compound treatment 0.318 -0.00906 -0.36 0.32 -0.0055 -0.12 -0.3333 -0.8902 1579979 IFLab1_005329 OC(COc1ccc(Cl)cc1Cl)CN2C(=O)c3ccccc3S2(=O)=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C06 compound treatment 0.35 0.0229 0.9 0.341 0.0155 0.32 0.8671 0.9047 2068241 IFLab1_005330 O=C(Nc1cccc(c1)c2nc3ccccc3[nH]2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C07 compound treatment 0.335 0.00794 0.31 0.332 0.0065 0.14 0.3169 0.9307 1462746 IFLab1_005331 Cc1cccc(n1)N2C(=O)c3cccc4cccc(C2=O)c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C08 compound treatment 0.326 -0.00106 -0.04 0.341 0.0155 0.32 0.1998 0.611 1554162 IFLab1_005332 OC(=O)CSc1cccc2cccnc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C09 compound treatment 0.341 0.0139 0.55 0.338 0.0125 0.26 0.5725 0.9427 2068242 IFLab1_005333 CC(C)(C)c1nnc(SCC(=O)Nc2ccc(Br)cc2)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C10 compound treatment 0.33 0.00294 0.12 0.331 0.0055 0.12 0.1631 1.0 2068243 IFLab1_005334 CCN1CCN(Cc2ccc3cccnc3c2O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C11 compound treatment 0.322 -0.00506 -0.2 0.323 -0.0025 -0.05 -0.1777 -0.8636 1873690 IFLab1_005335 CC(=O)Nc1ccc(OCC(O)CN2CCN(CC2)c3ccc(F)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C12 compound treatment 0.338 0.0109 0.43 0.336 0.0105 0.22 0.4595 0.9514 2068244 IFLab1_005336 Cc1nc2ccccc2nc1SCC(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C13 compound treatment 0.335 0.00794 0.31 0.336 0.0105 0.22 0.376 0.9853 2068245 IFLab1_005337 CCOC(=O)N1CCc2c(C#N)c(NC(=O)c3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C14 compound treatment 0.332 0.00494 0.19 0.332 0.0065 0.14 0.2335 0.9849 2068246 IFLab1_005338 Cc1nccn1CC(O)Cn2c3C(=O)CCCc3c4cc(C)ccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C15 compound treatment 0.343 0.0159 0.63 0.345 0.0195 0.41 0.7316 0.9784 2068247 IFLab1_005339 CC(=O)N1CCc2c(C#N)c(NC(=O)c3ccc(C#N)cc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C16 compound treatment 0.348 0.0209 0.82 0.35 0.0245 0.51 0.9446 0.974 2068248 IFLab1_005340 Cc1ccc(cc1)n2nnnc2c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C17 compound treatment 0.334 0.00694 0.27 0.335 0.0095 0.2 0.3334 0.9879 2068249 IFLab1_005341 COC(=O)c1ccc2nc(NC(=O)C(C)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C18 compound treatment 0.335 0.00794 0.31 0.334 0.0085 0.18 0.3465 0.9645 1623824 IFLab1_005342 CC(=O)Nc1ccccc1NS(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C19 compound treatment 0.378 0.0509 2.0 0.367 0.0415 0.87 2.0302 0.9301 2068250 IFLab1_005343 O=C(Nc1nc(cs1)c2ccc3OCCOc3c2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C20 compound treatment 0.332 0.00494 0.19 0.332 0.0065 0.14 0.2335 0.9849 1274031 IFLab1_005344 CC(C)(CO)NCC(O)Cn1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C21 compound treatment 0.333 0.00594 0.23 0.333 0.0075 0.16 0.2761 0.9813 2068251 IFLab1_005345 O=C(Nc1nc2CCCCc2s1)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C22 compound treatment 0.319 -0.00806 -0.32 0.32 -0.0055 -0.12 -0.3055 -0.906 1711097 IFLab1_005346 Clc1sc(Nc2ccccc2N3CCOCC3)nc1S(=O)(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C23 mock treatment 0.322 -0.00506 -0.2 0.321 -0.0045 -0.09 -0.2073 -0.9416 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 C24 positive control 0.079 -0.248 -9.75 0.08 -0.246 -5.14 -10.5293 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D01 compound treatment 0.349 0.0219 0.86 0.341 0.0155 0.32 0.8393 0.9107 2068252 IFLab1_005347 COC(=O)c1ccsc1NC(=O)c2ccc(cc2)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D02 compound treatment 0.324 -0.00306 -0.12 0.319 -0.0065 -0.14 -0.1813 -0.9982 2068253 IFLab1_005348 Clc1cc(C(=O)Nc2nnc(o2)c3ccccc3)c(Cl)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D03 compound treatment 0.329 0.00194 0.08 0.324 -0.0015 -0.03 0.0317 0.3844 2068254 IFLab1_005349 NC(=O)c1ccsc1NC(=O)c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D04 compound treatment 0.336 0.00894 0.35 0.333 0.0075 0.16 0.3595 0.934 2068255 IFLab1_005350 CCC(=O)Nc1nnc(o1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D05 compound treatment 0.338 0.0109 0.43 0.338 0.0125 0.26 0.489 0.9716 2068256 IFLab1_005351 CC(C)(C)c1ccc(cc1)C(=O)Nc2sccc2C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D06 compound treatment 0.332 0.00494 0.19 0.337 0.0115 0.24 0.3074 0.9943 2068257 IFLab1_005352 CCn1c(=NC(=O)c2ccc(cc2)N(C)C)sc3cc(Cl)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D07 compound treatment 0.34 0.0129 0.51 0.333 0.0075 0.16 0.4707 0.8841 2068258 IFLab1_005353 COCCn1c(=NC(=O)c2ccc(cc2)C(=O)OC)sc3cc(C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D08 compound treatment 0.36 0.0329 1.3 0.358 0.0325 0.68 1.3966 0.9548 2068259 IFLab1_005354 O=C(Nc1sccc1C#N)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D09 compound treatment 0.351 0.0239 0.94 0.347 0.0215 0.45 0.9836 0.9429 2068260 IFLab1_005355 COCCn1c(=NC(=O)c2ccccc2)sc3cc(NC(=O)C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D10 compound treatment 0.336 0.00894 0.35 0.335 0.0095 0.2 0.3891 0.9636 2068261 IFLab1_005356 O=C(Nc1sccc1C#N)C2CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D11 compound treatment 0.338 0.0109 0.43 0.338 0.0125 0.26 0.489 0.9716 2068262 IFLab1_005357 OC(=O)CNS(=O)(=O)c1ccccc1C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D12 compound treatment 0.376 0.0489 1.92 0.371 0.0455 0.95 2.0338 0.9474 2068263 IFLab1_005358 CCCCN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D13 compound treatment 0.379 0.0519 2.04 0.356 0.0305 0.64 1.8953 0.8859 2068264 IFLab1_005359 Cc1ccc(cc1)C(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D14 compound treatment 0.332 0.00494 0.19 0.326 5.0E-4 0.01 0.1447 0.7441 2068265 IFLab1_005360 CCOC(=O)c1ccc(OCC2NCCc3cc(OC)c(OC)cc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D15 compound treatment 0.328 9.38E-4 0.04 0.33 0.0045 0.09 0.0927 0.9162 2068266 IFLab1_005361 COC(=O)Cn1c(=NC(=O)C(C)C)sc2cc(Cl)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D16 compound treatment 0.321 -0.00606 -0.24 0.336 0.0105 0.22 -0.0132 -0.0407 2068267 IFLab1_005362 Cc1ccc(cc1)c2[nH]c3ccccc3c2SCCN 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D17 compound treatment 0.331 0.00394 0.15 0.331 0.0055 0.12 0.1909 0.9893 2068268 IFLab1_005363 CC1(C)C2(C)CCC1(CC2=O)C(=O)Nc3ncc(Cl)cc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D18 compound treatment 0.401 0.0739 2.91 0.399 0.0735 1.54 3.1432 0.9557 2068269 IFLab1_005364 S=C(NCC1CCCO1)SCc2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D19 compound treatment 0.336 0.00894 0.35 0.331 0.0055 0.12 0.3299 0.8921 2068270 IFLab1_005365 COc1ccccc1c2nnc(NC(=O)c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D20 compound treatment 0.336 0.00894 0.35 0.336 0.0105 0.22 0.4039 0.9744 2068271 IFLab1_005366 CS(=O)(=O)c1ccc(COC(=O)c2ccccc2O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D21 compound treatment 0.33 0.00294 0.12 0.331 0.0055 0.12 0.1631 1.0 2068272 IFLab1_005367 Clc1ccc(cc1)c2nnc(NC(=O)c3ccc4ncsc4c3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D22 compound treatment 0.332 0.00494 0.19 0.332 0.0065 0.14 0.2335 0.9849 2068273 IFLab1_005368 CN1CCN(CC1)C(c2c(NC(=O)C)sc3CCCCc23)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D23 mock treatment 0.32 -0.00706 -0.28 0.321 -0.0045 -0.09 -0.2629 -0.8967 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 D24 positive control 0.08 -0.247 -9.71 0.082 -0.243 -5.1 -10.4719 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E01 compound treatment 0.324 -0.00306 -0.12 0.329 0.0035 0.07 -0.0334 -0.2367 2068274 IFLab1_005369 CN1CCN(CC1)C(CC(=O)Nc2ccc(C)c(Cl)c2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E02 compound treatment 0.326 -0.00106 -0.04 0.316 -0.0095 -0.2 -0.1701 -0.8374 2068275 IFLab1_005370 O=C(Nc1cccc(c1)c2nc3ccccc3o2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E03 compound treatment 0.332 0.00494 0.19 0.328 0.0025 0.05 0.1743 0.8667 1920161 IFLab1_005371 CCOc1ccc2[nH]c(SCC)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E04 compound treatment 0.334 0.00694 0.27 0.328 0.0025 0.05 0.2299 0.8276 2068276 IFLab1_005372 CN(C(=O)C1=COCCO1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E05 compound treatment 0.333 0.00594 0.23 0.326 5.0E-4 0.01 0.1725 0.7381 1499088 IFLab1_005373 Clc1ccc(cc1)S(=O)(=O)NC2OC(=O)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E06 compound treatment 0.347 0.0199 0.78 0.352 0.0265 0.55 0.9464 0.9856 2068277 IFLab1_005374 O=C(Nc1nccs1)c2ccc(s2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E07 compound treatment 0.696 0.369 14.51 0.673 0.347 7.27 15.3992 0.949 2068278 IFLab1_005375 CN1/C(=C/C(=O)c2ccccc2)/Sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E08 compound treatment 0.348 0.0209 0.82 0.34 0.0145 0.3 0.7967 0.908 1867541 IFLab1_005376 CC1(C)C2(C)CCC1(CC2=O)C(=O)Nc3cccc4cccnc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E09 compound treatment 0.346 0.0189 0.74 0.338 0.0125 0.26 0.7115 0.9015 2068279 IFLab1_005377 Nn1c(SCC(=O)NC2CCCCC2)nnc1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E10 compound treatment 0.347 0.0199 0.78 0.345 0.0195 0.41 0.8428 0.9537 1417146 IFLab1_005378 CC1CCN(Cc2ccc(O)c3ncccc23)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E11 compound treatment 0.34 0.0129 0.51 0.34 0.0145 0.3 0.5742 0.9695 1873699 IFLab1_005379 CC(=O)Nc1ccc(OCC(O)Cn2cnc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E12 compound treatment 0.339 0.0119 0.47 0.337 0.0115 0.24 0.5021 0.9518 2068280 IFLab1_005380 O=C(CSc1cnc2ccccc2n1)NC3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E13 compound treatment 0.352 0.0249 0.98 0.338 0.0125 0.26 0.8783 0.8655 2068281 IFLab1_005381 CCOC(=O)N1CCc2c(C#N)c(NC(=O)/C=C/c3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E14 compound treatment 0.332 0.00494 0.19 0.331 0.0055 0.12 0.2187 0.9689 2068282 IFLab1_005382 CC(C)(C)NC(=O)C1C2CC(C)(Oc3ccccc23)N(CC=C)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E15 compound treatment 0.338 0.0109 0.43 0.338 0.0125 0.26 0.489 0.9716 2068283 IFLab1_005383 CC(C)C(=O)Nc1sc2CN(CCc2c1C#N)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E16 compound treatment 0.337 0.00994 0.39 0.33 0.0045 0.09 0.3429 0.8531 2068284 IFLab1_005384 Cn1cnnc1SC2C(NS(=O)(=O)C)c3cccc4cccc2c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E17 compound treatment 0.334 0.00694 0.27 0.332 0.0065 0.14 0.2891 0.9483 2068285 IFLab1_005385 COC(=O)c1ccc2nc(NC(=O)Cc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E18 compound treatment 0.327 -6.25E-5 0.0 0.329 0.0035 0.07 0.0501 0.683 1633840 IFLab1_005386 OC(CN1CCNCC1)Cn2c3ccccc3c4cc(Br)ccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E19 compound treatment 0.347 0.0199 0.78 0.353 0.0275 0.58 0.9612 0.9884 2068286 IFLab1_005387 O=C(Nc1nc(cs1)c2ccc3OCCOc3c2)/C=C/c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E20 compound treatment 0.334 0.00694 0.27 0.334 0.0085 0.18 0.3187 0.9785 1060202 IFLab1_005388 CC(C)(C)NC(=O)c1cccc2C(=O)c3ccccc3-c21 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E21 compound treatment 0.34 0.0129 0.51 0.339 0.0135 0.28 0.5594 0.9615 2068287 IFLab1_005389 Cc1nc2ccc3nc(NC(=O)C4=COCCO4)sc3c2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E22 compound treatment 0.289 -0.0381 -1.5 0.286 -0.0395 -0.83 -1.6427 -0.9608 2068288 IFLab1_005390 Cn1sc(=Nc2ccccc2)nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E23 mock treatment 0.32 -0.00706 -0.28 0.322 -0.0035 -0.07 -0.2481 -0.8641 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 E24 positive control 0.082 -0.245 -9.64 0.082 -0.243 -5.1 -10.4163 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F01 compound treatment 0.329 0.00194 0.08 0.336 0.0105 0.22 0.2092 0.8997 2068289 IFLab1_005391 CCOC(=O)c1ccsc1NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F02 compound treatment 0.329 0.00194 0.08 0.317 -0.0085 -0.18 -0.0719 -0.3716 2068290 IFLab1_005392 CC(C)(C)C(=O)Nc1nnc(o1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F03 compound treatment 0.366 0.0389 1.53 0.369 0.0435 0.91 1.7262 0.9692 2068291 IFLab1_005393 NC(=O)c1ccsc1NC(=O)c2ccc(Br)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F04 compound treatment 0.319 -0.00806 -0.32 0.318 -0.0075 -0.16 -0.3351 -0.9474 2068292 IFLab1_005394 Fc1ccc(/C=C/C(=O)Nc2ccon2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F05 compound treatment 0.357 0.0299 1.18 0.356 0.0305 0.64 1.2836 0.9587 2068293 IFLab1_005395 NC(=O)c1ccsc1NC(=O)C2COc3ccccc3O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F06 compound treatment 0.359 0.0319 1.26 0.343 0.0175 0.37 1.1469 0.8768 2068294 IFLab1_005396 CCn1c(=NC(=O)c2ccccc2OC)sc3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F07 compound treatment 0.321 -0.00606 -0.24 0.333 0.0075 0.16 -0.0576 -0.2017 2068295 IFLab1_005397 COCCn1c(=NC(=O)c2cccs2)sc3cc(ccc13)C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F08 compound treatment 0.354 0.0269 1.06 0.372 0.0465 0.97 1.437 0.9991 2068296 IFLab1_005398 O=C(Nc1sccc1C#N)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F09 compound treatment 0.341 0.0139 0.55 0.346 0.0205 0.43 0.6908 0.9927 2068297 IFLab1_005399 COCCn1c(=NC(=O)c2ccc(Br)s2)sc3cc(NC(=O)C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F10 compound treatment 0.345 0.0179 0.71 0.35 0.0245 0.51 0.8612 0.9877 2068298 IFLab1_005400 CCC(=O)Nc1sccc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F11 compound treatment 0.34 0.0129 0.51 0.338 0.0125 0.26 0.5447 0.9522 1260669 IFLab1_005401 Cc1cc(NCCN2CCOCC2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F12 compound treatment 0.342 0.0149 0.59 0.347 0.0215 0.45 0.7334 0.9913 2068299 IFLab1_005402 CN(C1CCCCC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3sccc3C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F13 compound treatment 0.367 0.0399 1.57 0.358 0.0325 0.68 1.5912 0.9299 2068300 IFLab1_005403 COc1ccc(cc1)C2C(=C(NC3=C2C(=O)CC(C)(C)C3)SC)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F14 compound treatment 0.337 0.00994 0.39 0.343 0.0175 0.37 0.5352 0.9995 2068301 IFLab1_005404 NC(=N)Sc1cn(Cc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F15 compound treatment 0.343 0.0159 0.63 0.34 0.0145 0.3 0.6577 0.9446 2068302 IFLab1_005405 COC(=O)Cn1c(=NC(=O)C)sc2cc(Br)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F16 compound treatment 0.324 -0.00306 -0.12 0.329 0.0035 0.07 -0.0334 -0.2367 2068303 IFLab1_005406 COc1ccc(cc1)n2cc(c3ccccc3)c4c(O)ncnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F17 compound treatment 0.349 0.0219 0.86 0.339 0.0135 0.28 0.8097 0.8921 2068304 IFLab1_005407 FC(F)(F)c1nn(c2CCCCc12)c3ccc(cc3)C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F18 compound treatment 0.33 0.00294 0.12 0.32 -0.0055 -0.12 3.0E-4 0.0017 2068305 IFLab1_005408 NCc1ccc2[nH]c3CCCCc3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F19 compound treatment 0.341 0.0139 0.55 0.354 0.0285 0.6 0.8092 0.9991 2068306 IFLab1_005409 COc1ccccc1c2nnc(NC(=O)CCSc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F20 compound treatment 0.37 0.0429 1.69 0.363 0.0375 0.78 1.7486 0.9393 2068307 IFLab1_005410 OC1=C(C(=O)/C=C/c2ccco2)C(=O)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F21 compound treatment 0.345 0.0179 0.71 0.337 0.0115 0.24 0.6689 0.8976 2068308 IFLab1_005411 Clc1ccc(cc1)c2nnc(NC(=O)COc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F22 compound treatment 0.339 0.0119 0.47 0.331 0.0055 0.12 0.4133 0.8552 2068309 IFLab1_005412 CC(=O)Nc1sc2CCCCc2c1C(N3CCN(CCO)CC3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F23 mock treatment 0.324 -0.00306 -0.12 0.328 0.0025 0.05 -0.0482 -0.3668 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 F24 positive control 0.082 -0.245 -9.64 0.082 -0.243 -5.1 -10.4163 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G01 compound treatment 0.339 0.0119 0.47 0.328 0.0025 0.05 0.3689 0.7811 2068310 IFLab1_005413 CN(C)C(CC(=O)Nc1cc(Cl)ccc1C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G02 compound treatment 0.368 0.0409 1.61 0.349 0.0235 0.49 1.4859 0.8829 2068311 IFLab1_005414 CSc1nc2ccc3nc(NC(=O)C4=COCCO4)sc3c2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G03 compound treatment 0.312 -0.0151 -0.59 0.31 -0.0155 -0.32 -0.6481 -0.9598 1231753 IFLab1_005415 CCOc1ccc2[nH]c(SCCN(C)C)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G04 compound treatment 0.335 0.00794 0.31 0.32 -0.0055 -0.12 0.1393 0.4188 2068312 IFLab1_005416 O=C(N1CCN(CC1)c2ccccc2)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G05 compound treatment 0.307 -0.0201 -0.79 0.317 -0.0085 -0.18 -0.6836 -0.8453 2068313 IFLab1_005417 CN1C(=O)/C(=C\C=C\c2ccccc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G06 compound treatment 0.37 0.0429 1.69 0.377 0.0515 1.08 1.9558 0.9765 2068314 IFLab1_005418 O=C(NCc1ccccc1)c2ccc(s2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G07 compound treatment 0.343 0.0159 0.63 0.333 0.0075 0.16 0.5541 0.8577 2068315 IFLab1_005419 C1Cn2cc(nc2S1)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G08 compound treatment 0.344 0.0169 0.67 0.342 0.0165 0.35 0.715 0.9532 1873796 IFLab1_005420 CC1(C)C2CCC(C2)(C(=O)Nc3ccc(Br)cn3)C1=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G09 compound treatment 0.328 9.38E-4 0.04 0.333 0.0075 0.16 0.137 0.85 1708050 IFLab1_005421 Cc1nnc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G10 compound treatment 0.327 -6.25E-5 0.0 0.331 0.0055 0.12 0.0796 0.6919 2068316 IFLab1_005422 FC(F)(F)c1cc(NC(=O)CC2SC(=N)NC2=O)ccc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G11 compound treatment 0.336 0.00894 0.35 0.321 -0.0045 -0.09 0.1819 0.5 2068317 IFLab1_005423 COC(=O)/C=C/1\SC(=N)NC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G12 compound treatment 0.327 -6.25E-5 0.0 0.31 -0.0155 -0.32 -0.2311 -0.7124 2068318 IFLab1_005424 Fc1ccc(cc1)N2CCN(CC2)C(=O)CSc3cnc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G13 compound treatment 0.384 0.0569 2.24 0.378 0.0525 1.1 2.3598 0.9463 2068319 IFLab1_005425 CC(=O)N1CCc2c(C(=O)N)c(NC(=O)c3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G14 compound treatment 0.333 0.00594 0.23 0.328 0.0025 0.05 0.2021 0.8446 2068320 IFLab1_005426 CC1(CC2C(C(=O)Nc3ccccc3)C(=O)N1CC=C)Oc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G15 compound treatment 0.34 0.0129 0.51 0.338 0.0125 0.26 0.5447 0.9522 2068321 IFLab1_005427 CC(=O)N1CCc2c(C#N)c(NC(=O)Cc3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G16 compound treatment 0.347 0.0199 0.78 0.35 0.0245 0.51 0.9168 0.9788 2068322 IFLab1_005428 COc1ccc(cc1)c2ccc(o2)C3C(=C(N)OC4=C3C(=O)CCC4)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G17 compound treatment 0.353 0.0259 1.02 0.355 0.0295 0.62 1.1576 0.9711 2068323 IFLab1_005429 CCOC(=O)c1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G18 compound treatment 0.333 0.00594 0.23 0.333 0.0075 0.16 0.2761 0.9813 2068324 IFLab1_005430 COC(=O)c1cccc2/C(=N\O)/c3ccccc3-c21 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G19 compound treatment 0.325 -0.00206 -0.08 0.332 0.0065 0.14 0.0388 0.2453 2068325 IFLab1_005431 O=C(Nc1nc(cs1)c2ccc3OCCOc3c2)C4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G20 compound treatment 0.332 0.00494 0.19 0.319 -0.0065 -0.14 0.0411 0.1733 1424207 IFLab1_005432 Cc1ccc(cc1)S(=O)(=O)NCC(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G21 compound treatment 0.334 0.00694 0.27 0.327 0.0015 0.03 0.2151 0.7833 2068326 IFLab1_005433 O=C(Nc1nc(cs1)c2ccccc2)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G22 compound treatment 0.283 -0.0441 -1.73 0.278 -0.0475 -0.99 -1.9279 -0.9652 2068327 IFLab1_005434 C[N+](=c1nc(c2ccccc2)n(C)s1)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G23 mock treatment 0.318 -0.00906 -0.36 0.317 -0.0085 -0.18 -0.3777 -0.9485 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 G24 positive control 0.082 -0.245 -9.64 0.082 -0.243 -5.1 -10.4163 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H01 compound treatment 0.352 0.0249 0.98 0.334 0.0085 0.18 0.8191 0.822 2068328 IFLab1_005435 CCOC(=O)c1ccsc1NC(=O)c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H02 compound treatment 0.326 -0.00106 -0.04 0.313 -0.0125 -0.26 -0.2145 -0.8098 2068329 IFLab1_005436 COc1ccccc1C(=O)Nc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H03 compound treatment 0.362 0.0349 1.37 0.35 0.0245 0.51 1.3339 0.9097 2068330 IFLab1_005437 Cc1ccc(cc1C)C(=O)Nc2sccc2C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H04 compound treatment 0.332 0.00494 0.19 0.334 0.0085 0.18 0.263 0.999 2068331 IFLab1_005438 Cc1cc(C)n(n1)C(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H05 compound treatment 0.365 0.0379 1.49 0.369 0.0435 0.91 1.6984 0.9719 2068332 IFLab1_005439 NC(=O)c1ccsc1NC(=O)c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H06 compound treatment 0.352 0.0249 0.98 0.334 0.0085 0.18 0.8191 0.822 2068333 IFLab1_005440 CCn1c(=NC(=O)Cc2ccccc2)sc3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H07 compound treatment 0.339 0.0119 0.47 0.339 0.0135 0.28 0.5316 0.9705 2068334 IFLab1_005441 COCCn1c(=NC(=O)C)sc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H08 compound treatment 0.368 0.0409 1.61 0.369 0.0435 0.91 1.7818 0.9636 2068335 IFLab1_005442 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H09 compound treatment 0.353 0.0259 1.02 0.343 0.0175 0.37 0.9801 0.9045 2068336 IFLab1_005443 COCCn1c(=NC(=O)CCc2ccccc2)sc3cc(NC(=O)C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H10 compound treatment 0.342 0.0149 0.59 0.342 0.0165 0.35 0.6594 0.9679 2068337 IFLab1_005444 CC(C)C(=O)Nc1sccc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H11 compound treatment 0.341 0.0139 0.55 0.337 0.0115 0.24 0.5577 0.9317 2068338 IFLab1_005445 CN(C)C(=O)CSc1nnc2sc3ccccc3n12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H12 compound treatment 0.343 0.0159 0.63 0.344 0.0185 0.39 0.7168 0.9732 2068339 IFLab1_005446 O=C(Nc1sccc1C#N)c2ccc3ncsc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H13 compound treatment 0.353 0.0259 1.02 0.344 0.0185 0.39 0.9949 0.912 1571330 IFLab1_005447 c1ccc2[nH]c(nc2c1)c3nc4ccccc4o3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H14 compound treatment 0.342 0.0149 0.59 0.34 0.0145 0.3 0.6299 0.9528 2068340 IFLab1_005448 Cn1cc(SC(=N)N)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H15 compound treatment 0.365 0.0379 1.49 0.375 0.0495 1.04 1.7872 0.9841 2068341 IFLab1_005449 COC(=O)Cn1c(=NC(=O)/C=C/c2cccs2)sc3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H16 compound treatment 0.338 0.0109 0.43 0.326 5.0E-4 0.01 0.3115 0.7241 2068342 IFLab1_005450 Cc1cccc(c1)n2cc(c3ccccc3)c4c(O)ncnc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H17 compound treatment 0.344 0.0169 0.67 0.339 0.0135 0.28 0.6707 0.9271 1867614 IFLab1_005451 CC1(C)C2(C)CCC1(OC2=O)C(=O)Nc3ccc(Br)cn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H18 compound treatment 0.324 -0.00306 -0.12 0.321 -0.0045 -0.09 -0.1517 -0.9926 2068343 IFLab1_005452 Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H19 compound treatment 0.33 0.00294 0.12 0.327 0.0015 0.03 0.1039 0.8678 1574318 IFLab1_005453 COc1ccc(cc1)c2nnc(NC(=O)C)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H20 compound treatment 0.355 0.0279 1.1 0.352 0.0265 0.55 1.1688 0.9499 2068344 IFLab1_005454 COc1ccc(cc1)C(=O)C2=C(O)c3ccccc3C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H21 compound treatment 0.337 0.00994 0.39 0.334 0.0085 0.18 0.4021 0.9365 2068345 IFLab1_005455 O=C(Nc1nnc(o1)c2ccccc2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H22 compound treatment 0.336 0.00894 0.35 0.331 0.0055 0.12 0.3299 0.8921 2068346 IFLab1_005456 CC(=O)Nc1sc2CCCCc2c1C(N3CCOCC3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H23 mock treatment 0.323 -0.00406 -0.16 0.32 -0.0055 -0.12 -0.1943 -0.9871 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 H24 positive control 0.084 -0.243 -9.56 0.084 -0.241 -5.05 -10.3311 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I01 compound treatment 0.346 0.0189 0.74 0.331 0.0055 0.12 0.6079 0.8068 2068347 IFLab1_005457 Cc1ccc(Cl)cc1NC(=O)CC(N2CCNCC2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I02 compound treatment 0.328 9.38E-4 0.04 0.327 0.0015 0.03 0.0483 0.9968 2068348 IFLab1_005458 COc1cccc2sc(=NC(=O)C3=COCCO3)n(C)c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I03 compound treatment 0.335 0.00794 0.31 0.333 0.0075 0.16 0.3317 0.9494 1869881 IFLab1_005459 CCOc1ccc2nc3SCC(O)Cn3c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I04 compound treatment 0.329 0.00194 0.08 0.334 0.0085 0.18 0.1796 0.9284 2068349 IFLab1_005460 Cc1cc(NC(=O)C2=COCCO2)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I05 compound treatment 0.331 0.00394 0.15 0.336 0.0105 0.22 0.2648 0.9853 2068350 IFLab1_005461 CN1C(=O)/C(=C\c2ccc(Cl)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I06 compound treatment 0.343 0.0159 0.63 0.338 0.0125 0.26 0.6281 0.9249 2068351 IFLab1_005462 O=C(N1CCOCC1)c2ccc(s2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I07 compound treatment 0.349 0.0219 0.86 0.351 0.0255 0.53 0.9872 0.9734 555 IFLab1_005463 Cc1cc2ncc(nc2cc1C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I08 compound treatment 0.34 0.0129 0.51 0.337 0.0115 0.24 0.5299 0.9416 1868510 IFLab1_005464 OC(=O)Cc1coc2ccc3ccccc3c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I09 compound treatment 0.345 0.0179 0.71 0.342 0.0165 0.35 0.7429 0.946 1177865 IFLab1_005465 CCc1nnc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I10 compound treatment 0.342 0.0149 0.59 0.341 0.0155 0.32 0.6446 0.9608 2068352 IFLab1_005466 CN(C)c1ccc(NC(=O)CC2SC(=N)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I11 compound treatment 0.342 0.0149 0.59 0.341 0.0155 0.32 0.6446 0.9608 2068353 IFLab1_005467 FC(F)(F)c1cc(NC2OC(=O)c3ccccc23)ccc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I12 compound treatment 0.349 0.0219 0.86 0.343 0.0175 0.37 0.8689 0.9272 2068354 IFLab1_005468 Fc1ccc(NC(=O)CSc2cnc3ccccc3n2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I13 compound treatment 0.373 0.0459 1.81 0.37 0.0445 0.93 1.9356 0.9525 2068355 IFLab1_005469 CC(=O)N1CCc2c(C(=O)N)c(NC(=O)/C=C/c3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I14 compound treatment 0.322 -0.00506 -0.2 0.34 0.0145 0.3 0.0738 0.2034 2068356 IFLab1_005470 CCC(CC)NC(=O)C1C2CC(C)(Oc3ccccc23)N(C)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I15 compound treatment 0.319 -0.00806 -0.32 0.312 -0.0135 -0.28 -0.4239 -0.9983 2068357 IFLab1_005471 CC(C)C(=O)Nc1sc2CN(CCc2c1c3nc4ccccc4s3)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I16 compound treatment 0.334 0.00694 0.27 0.332 0.0065 0.14 0.2891 0.9483 2068358 IFLab1_005472 N/C(=N\S(=O)(=O)c1ccc(Cl)s1)/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I17 compound treatment 0.341 0.0139 0.55 0.339 0.0135 0.28 0.5873 0.9525 2068359 IFLab1_005473 CCOC(=O)c1ccc2nc(NC(=O)C(C)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I18 compound treatment 0.339 0.0119 0.47 0.337 0.0115 0.24 0.5021 0.9518 3177232 IFLab1_005474 CCN(CC)CC(O)Cn1c2ccccc2c3ccccc13.OC(=O)c1ccco1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I19 compound treatment 0.338 0.0109 0.43 0.334 0.0085 0.18 0.4299 0.9237 2068360 IFLab1_005475 CCC(=O)Nc1nc(cs1)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I20 compound treatment 0.34 0.0129 0.51 0.342 0.0165 0.35 0.6038 0.9822 1190658 IFLab1_005476 CCC(NS(=O)(=O)c1ccc(C)cc1)C(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I21 compound treatment 0.337 0.00994 0.39 0.342 0.0165 0.35 0.5204 0.9981 2068361 IFLab1_005477 Clc1ccc(s1)c2csc(NC(=O)C3=COCCO3)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I22 compound treatment 0.324 -0.00306 -0.12 0.325 -5.0E-4 -0.01 -0.0925 -0.7657 2068362 IFLab1_005478 Cc1ccc(cc1)S(=O)(=O)c2nc(Nc3nccs3)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I23 mock treatment 0.333 0.00594 0.23 0.332 0.0065 0.14 0.2613 0.9669 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 I24 positive control 0.086 -0.241 -9.48 0.085 -0.24 -5.03 -10.2607 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J01 compound treatment 0.335 0.00794 0.31 0.33 0.0045 0.09 0.2873 0.8812 2068363 IFLab1_005479 CCOC(=O)c1ccsc1NC(=O)C2CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J02 compound treatment 0.326 -0.00106 -0.04 0.323 -0.0025 -0.05 -0.0665 -0.9938 2068364 IFLab1_005480 O=C(CCc1ccccc1)Nc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J03 compound treatment 0.324 -0.00306 -0.12 0.316 -0.0095 -0.2 -0.2257 -0.9711 2068365 IFLab1_005481 NC(=O)c1ccsc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J04 compound treatment 0.389 0.0619 2.44 0.385 0.0595 1.25 2.6024 0.9515 2068366 IFLab1_005482 Fc1cccc(/C=C/C(=O)Nc2ccc3OCOc3c2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J05 compound treatment 0.326 -0.00106 -0.04 0.332 0.0065 0.14 0.0666 0.4683 2068367 IFLab1_005483 NC(=O)c1ccsc1NC(=O)C2=COCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J06 compound treatment 0.336 0.00894 0.35 0.335 0.0095 0.2 0.3891 0.9636 2068368 IFLab1_005484 CCn1c(=NC(=O)c2ccc(Br)s2)sc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J07 compound treatment 0.323 -0.00406 -0.16 0.324 -0.0015 -0.03 -0.1351 -0.8302 2068369 IFLab1_005485 COCCn1c(=NC(=O)C2COc3ccccc3O2)sc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J08 compound treatment 0.353 0.0259 1.02 0.356 0.0305 0.64 1.1724 0.9745 2068370 IFLab1_005486 O=C(Nc1sccc1C#N)c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J09 compound treatment 0.338 0.0109 0.43 0.336 0.0105 0.22 0.4595 0.9514 2068371 IFLab1_005487 COCCn1c(=NC(=O)c2ccccc2OC)sc3cc(OC)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J10 compound treatment 0.353 0.0259 1.02 0.347 0.0215 0.45 1.0393 0.9324 2068372 IFLab1_005488 COc1ccccc1C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J11 compound treatment 0.333 0.00594 0.23 0.355 0.0295 0.62 0.6016 0.9115 2068373 IFLab1_005489 O=c1[nH]c(CN2CCOCC2)nc3sc4CCCCc4c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J12 compound treatment 0.337 0.00994 0.39 0.348 0.0225 0.47 0.6092 0.9957 2068374 IFLab1_005490 O=C(CCSc1ccccc1)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J13 compound treatment 0.341 0.0139 0.55 0.337 0.0115 0.24 0.5577 0.9317 2068375 IFLab1_005491 COC(=O)c1ccc2n(CC=C)c(=NC(=O)c3ccc(F)cc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J14 compound treatment 0.344 0.0169 0.67 0.34 0.0145 0.3 0.6855 0.9366 2068376 IFLab1_005492 CCn1cc(SC(=N)N)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J15 compound treatment 0.342 0.0149 0.59 0.339 0.0135 0.28 0.6151 0.9437 2068377 IFLab1_005493 CCOC(=O)Cn1c(=NC(=O)c2ccccc2Br)sc3cc(C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J16 compound treatment 0.329 0.00194 0.08 0.323 -0.0025 -0.05 0.0169 0.1826 2068378 IFLab1_005494 Oc1ncnc2n(cc(c3ccccc3)c12)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J17 compound treatment 0.337 0.00994 0.39 0.336 0.0105 0.22 0.4317 0.9629 2068379 IFLab1_005495 OC(=O)c1ccc(cc1)n2nc(c3CCCCc32)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J18 compound treatment 0.331 0.00394 0.15 0.335 0.0095 0.2 0.25 0.9924 2068380 IFLab1_005496 Cc1[nH]c2ccccc2c1C(N3CCCC3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J19 compound treatment 0.341 0.0139 0.55 0.34 0.0145 0.3 0.602 0.9611 2068381 IFLab1_005497 COc1ccc(cc1)c2nnc(NC(=O)/C=C/c3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J20 compound treatment 0.36 0.0329 1.3 0.352 0.0265 0.55 1.3079 0.9284 2068382 IFLab1_005498 CN(C)c1ccc(/C=C/C(=O)C2=C(O)c3ccccc3C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J21 compound treatment 0.339 0.0119 0.47 0.34 0.0145 0.3 0.5464 0.9777 2068383 IFLab1_005499 FC(F)(F)c1cccc(c1)C(=O)Nc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J22 compound treatment 0.331 0.00394 0.15 0.333 0.0075 0.16 0.2204 1.0 2068384 IFLab1_005500 CC(=O)Nc1sc2CCCCc2c1CN3CCc4ccccc4C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J23 mock treatment 0.326 -0.00106 -0.04 0.326 5.0E-4 0.01 -0.0221 -0.5141 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 J24 positive control 0.086 -0.241 -9.48 0.086 -0.239 -5.01 -10.2459 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K01 compound treatment 0.347 0.0199 0.78 0.334 0.0085 0.18 0.6801 0.846 2068385 IFLab1_005501 Cc1ccc(Cl)cc1NC(=O)CC(NCC2CCCO2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K02 compound treatment 0.32 -0.00706 -0.28 0.317 -0.0085 -0.18 -0.3221 -0.9768 2068386 IFLab1_005502 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K03 compound treatment 0.309 -0.0181 -0.71 0.301 -0.0245 -0.51 -0.8647 -0.9872 1869885 IFLab1_005503 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CCN2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K04 compound treatment 0.33 0.00294 0.12 0.336 0.0105 0.22 0.237 0.9549 2068387 IFLab1_005504 O=C(Nc1ccccc1c2nc3ccccc3[nH]2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K05 compound treatment 0.463 0.136 5.34 0.456 0.131 2.73 5.7104 0.9514 2068388 IFLab1_005505 CN1C(=O)/C(=C\c2ccc(O)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K06 compound treatment 0.337 0.00994 0.39 0.338 0.0125 0.26 0.4612 0.981 2068389 IFLab1_005506 O=C(N1CCCCC1)c2ccc(s2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K07 compound treatment 0.344 0.0169 0.67 0.341 0.0155 0.32 0.7003 0.9453 1005966 IFLab1_005507 COc1ccccc1OCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K08 compound treatment 0.334 0.00694 0.27 0.331 0.0055 0.12 0.2743 0.9264 2068390 IFLab1_005508 COC(=O)CSc1nnc(c2cccs2)n1c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K09 compound treatment 0.336 0.00894 0.35 0.339 0.0135 0.28 0.4482 0.9941 1873702 IFLab1_005509 CCN(CC)CC(O)COc1ccc(NC(=O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K10 compound treatment 0.335 0.00794 0.31 0.342 0.0165 0.35 0.4648 0.9987 2068391 IFLab1_005510 CC(C)OCC(O)CN1CCN(Cc2ccccc2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K11 compound treatment 0.334 0.00694 0.27 0.341 0.0155 0.32 0.4222 0.9963 2068392 IFLab1_005511 Cc1c(Cl)cccc1NC2OC(=O)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K12 compound treatment 0.34 0.0129 0.51 0.346 0.0205 0.43 0.663 0.9964 2068393 IFLab1_005512 O=C(CSc1nc2ccccc2nc1c3ccccc3)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K13 compound treatment 0.341 0.0139 0.55 0.346 0.0205 0.43 0.6908 0.9927 2068394 IFLab1_005513 CC(C)C(=O)Nc1sc2CN(CCc2c1C(=O)N)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K14 compound treatment 0.34 0.0129 0.51 0.343 0.0175 0.37 0.6186 0.987 2068395 IFLab1_005514 CCN(CC)C(=O)C1C2CC(C)(NC1=O)Oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K15 compound treatment 0.343 0.0159 0.63 0.344 0.0185 0.39 0.7168 0.9732 2068396 IFLab1_005515 COC(=O)c1ccc2nc(NC(=O)C)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K16 compound treatment 0.344 0.0169 0.67 0.343 0.0175 0.37 0.7298 0.9603 2068397 IFLab1_005516 O=S(=O)(/N=C(\NC#N)/c1ccccc1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K17 compound treatment 0.355 0.0279 1.1 0.353 0.0275 0.58 1.1836 0.9545 2068398 IFLab1_005517 CCCC(=O)Nc1nc2ccc(cc2s1)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K18 compound treatment 0.34 0.0129 0.51 0.342 0.0165 0.35 0.6038 0.9822 1453602 IFLab1_005518 OCCN(CCO)CC(O)Cn1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K19 compound treatment 0.337 0.00994 0.39 0.335 0.0095 0.2 0.4169 0.9509 2068399 IFLab1_005519 Cc1nc2ccc(NC(=O)C3=COCCO3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K20 compound treatment 0.337 0.00994 0.39 0.337 0.0115 0.24 0.4464 0.9729 1142721 IFLab1_005520 COc1ccccc1N(CC(O)CN2CCCCC2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K21 compound treatment 0.337 0.00994 0.39 0.338 0.0125 0.26 0.4612 0.981 2068400 IFLab1_005521 CC(C)(C)c1csc(NC(=O)C2=COCCO2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K22 compound treatment 0.339 0.0119 0.47 0.336 0.0105 0.22 0.4873 0.9402 2068401 IFLab1_005522 Clc1sc(nc1S(=O)(=O)c2ccc(Cl)cc2)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K23 mock treatment 0.323 -0.00406 -0.16 0.322 -0.0035 -0.07 -0.1647 -0.9375 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 K24 positive control 0.087 -0.24 -9.44 0.087 -0.238 -4.99 -10.2033 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L01 compound treatment 0.343 0.0159 0.63 0.327 0.0015 0.03 0.4653 0.7416 2068402 IFLab1_005523 CCOC(=O)c1ccsc1NC(=O)CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L02 compound treatment 0.32 -0.00706 -0.28 0.317 -0.0085 -0.18 -0.3221 -0.9768 2068403 IFLab1_005524 O=C(Cc1ccccc1)Nc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L03 compound treatment 0.324 -0.00306 -0.12 0.316 -0.0095 -0.2 -0.2257 -0.9711 2068404 IFLab1_005525 NC(=O)c1ccsc1NC(=O)c2cc(=O)c3ccccc3o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L04 compound treatment 0.316 -0.0111 -0.43 0.315 -0.0105 -0.22 -0.4629 -0.95 2068405 IFLab1_005526 Cn1c(=NC(=O)c2ccc(Cl)s2)sc3cccc(Cl)c13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L05 compound treatment 0.375 0.0479 1.88 0.369 0.0435 0.91 1.9764 0.9443 2068406 IFLab1_005527 NC(=O)c1ccsc1NC(=O)c2sc3ccccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L06 compound treatment 0.111 -0.216 -8.5 0.111 -0.215 -4.49 -9.181 -0.9555 1067560 IFLab1_005528 COc1ccc(CCN2C(=O)C=CC2=O)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L07 compound treatment 0.334 0.00694 0.27 0.33 0.0045 0.09 0.2595 0.8991 2068407 IFLab1_005529 COCCn1c(=NC(=O)c2cccc(OC)c2)sc3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L08 compound treatment 0.387 0.0599 2.36 0.375 0.0495 1.04 2.3988 0.9319 2068408 IFLab1_005530 Brc1ccc(s1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L09 compound treatment 0.324 -0.00306 -0.12 0.33 0.0045 0.09 -0.0186 -0.1214 2068409 IFLab1_005531 COCCn1c(=NC(=O)c2c(F)cccc2F)sc3cc(OC)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L10 compound treatment 0.348 0.0209 0.82 0.349 0.0235 0.49 0.9298 0.9697 2068410 IFLab1_005532 CCOc1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L11 compound treatment 0.336 0.00894 0.35 0.336 0.0105 0.22 0.4039 0.9744 2068411 IFLab1_005533 Fc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L12 compound treatment 0.354 0.0269 1.06 0.348 0.0225 0.47 1.0819 0.9334 2068412 IFLab1_005534 COc1ccc(cc1)n2ncc3c(O)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L13 compound treatment 0.333 0.00594 0.23 0.335 0.0095 0.2 0.3056 0.9968 2068413 IFLab1_005535 CS(=O)(=O)c1ccc2n(CC=C)c(=NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L14 compound treatment 0.334 0.00694 0.27 0.338 0.0125 0.26 0.3778 0.9998 2068414 IFLab1_005536 NC(=N)Sc1cn(CCNC(=O)c2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L15 compound treatment 0.342 0.0149 0.59 0.338 0.0125 0.26 0.6003 0.9336 1867568 IFLab1_005537 CCN1CCN(CC1)C(=O)C2(CCC3(C)C(=O)O2)C3(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L16 compound treatment 0.336 0.00894 0.35 0.333 0.0075 0.16 0.3595 0.934 1032585 IFLab1_005538 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L17 compound treatment 0.348 0.0209 0.82 0.348 0.0225 0.47 0.915 0.9649 1475400 IFLab1_005539 Oc1ccccc1C(=O)NS(=O)(=O)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L18 compound treatment 0.331 0.00394 0.15 0.333 0.0075 0.16 0.2204 1.0 2068415 IFLab1_005540 OCCCc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L19 compound treatment 0.339 0.0119 0.47 0.335 0.0095 0.2 0.4725 0.9269 2068416 IFLab1_005541 COc1ccc(cc1)C(=O)Nc2nnc(o2)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L20 compound treatment 0.345 0.0179 0.71 0.337 0.0115 0.24 0.6689 0.8976 2068417 IFLab1_005542 CCOC(=O)c1sc2nc3CCCc3c(c4ccc(OC)cc4)c2c1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L21 compound treatment 0.335 0.00794 0.31 0.33 0.0045 0.09 0.2873 0.8812 2068418 IFLab1_005543 O=C(Nc1nnc(o1)c2ccccc2)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L22 compound treatment 0.333 0.00594 0.23 0.337 0.0115 0.24 0.3352 0.9999 2068419 IFLab1_005544 Cc1sc(NC(=O)c2ccco2)c(C(N3CCCCC3)c4cccnc4)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L23 mock treatment 0.309 -0.0181 -0.71 0.327 0.0015 0.03 -0.48 -0.6752 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 L24 positive control 0.089 -0.238 -9.36 0.088 -0.237 -4.97 -10.1329 -0.9561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M01 compound treatment 0.324 -0.00306 -0.12 0.324 -0.0015 -0.03 -0.1073 -0.8626 2068420 IFLab1_005545 OC(=O)C(CC(=O)Nc1ccc(Cl)cc1Cl)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M02 compound treatment 0.341 0.0139 0.55 0.329 0.0035 0.07 0.4393 0.7945 2068421 IFLab1_005546 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M03 compound treatment 0.302 -0.0251 -0.99 0.317 -0.0085 -0.18 -0.8226 -0.8215 1635497 IFLab1_005547 OC(=O)c1cccnc1SCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M04 compound treatment 0.327 -6.25E-5 0.0 0.319 -0.0065 -0.14 -0.0979 -0.7198 2068422 IFLab1_005548 NC(=O)c1c(NC(=O)C2=COCCO2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M05 compound treatment 0.32 -0.00706 -0.28 0.329 0.0035 0.07 -0.1446 -0.5034 2068423 IFLab1_005549 COc1ccc(/C=C\2/SC(=S)N(C)C2=O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M06 compound treatment 0.343 0.0159 0.63 0.344 0.0185 0.39 0.7168 0.9732 2068424 IFLab1_005550 CN(C(=O)c1ccc(s1)c2nc3ccccc3s2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M07 compound treatment 0.338 0.0109 0.43 0.337 0.0115 0.24 0.4743 0.9624 1517122 IFLab1_005551 COc1ccc(C(=O)CNc2cc(C)ccc2C)c(F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M08 compound treatment 0.347 0.0199 0.78 0.351 0.0255 0.53 0.9316 0.9824 1635494 IFLab1_005552 OC(c1c[nH]c2ccccc12)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M09 compound treatment 0.333 0.00594 0.23 0.337 0.0115 0.24 0.3352 0.9999 1873677 IFLab1_005553 CC1CCCC(C)N1CC(O)COc2ccc(NC(=O)C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M10 compound treatment 0.342 0.0149 0.59 0.333 0.0075 0.16 0.5263 0.8657 2068425 IFLab1_005554 CC(C)OCC(O)CN1CCN(CC1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M11 compound treatment 0.343 0.0159 0.63 0.342 0.0165 0.35 0.6872 0.9606 2068426 IFLab1_005555 Cc1ccc(NC2OC(=O)c3ccccc23)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M12 compound treatment 0.355 0.0279 1.1 0.353 0.0275 0.58 1.1836 0.9545 2068427 IFLab1_005556 O=C(CSc1nccc2ccccc12)N3CCN(CC3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M13 compound treatment 0.341 0.0139 0.55 0.339 0.0135 0.28 0.5873 0.9525 2068428 IFLab1_005557 CC(=O)N1CCc2c(C(=O)N)c(NC(=O)Cc3ccccc3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M14 compound treatment 0.342 0.0149 0.59 0.343 0.0175 0.37 0.6742 0.9742 2068429 IFLab1_005558 CCN(CC)C(=O)C1C2C3CCCCC3(NC1=O)Oc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M15 compound treatment 0.342 0.0149 0.59 0.343 0.0175 0.37 0.6742 0.9742 2068430 IFLab1_005559 COC(=O)c1ccc2nc(NC(=O)c3ccco3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M16 compound treatment 0.344 0.0169 0.67 0.345 0.0195 0.41 0.7594 0.9724 2068431 IFLab1_005560 CC(C)(C)c1ccc(OCc2nc3ccccc3[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M17 compound treatment 0.344 0.0169 0.67 0.333 0.0075 0.16 0.5819 0.8505 2068432 IFLab1_005561 CCC(=O)Nc1nc2c(C)c(C)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M18 compound treatment 0.331 0.00394 0.15 0.343 0.0175 0.37 0.3684 0.9266 1186605 IFLab1_005562 CC1CC(C)CN(CC(O)Cn2c3ccccc3c4ccccc24)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M19 compound treatment 0.336 0.00894 0.35 0.34 0.0145 0.3 0.463 0.9973 2068433 IFLab1_005563 CSc1nc2ccc(NC(=O)C3=COCCO3)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M20 compound treatment 0.347 0.0199 0.78 0.339 0.0135 0.28 0.7541 0.905 1636064 IFLab1_005564 Cc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)C(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M21 compound treatment 0.336 0.00894 0.35 0.347 0.0215 0.45 0.5666 0.9925 2068434 IFLab1_005565 O=C(Nc1sc2CCCc2c1C#N)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M22 compound treatment 0.344 0.0169 0.67 0.342 0.0165 0.35 0.715 0.9532 2068435 IFLab1_005566 Cc1cccc(/N=C\2/NC(=O)C(Cc3cccc(c3)C(F)(F)F)S2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M23 mock treatment 0.333 0.00594 0.23 0.332 0.0065 0.14 0.2613 0.9669 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 M24 positive control 0.091 -0.236 -9.28 0.091 -0.234 -4.91 -10.0329 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N01 compound treatment 0.332 0.00494 0.19 0.329 0.0035 0.07 0.1891 0.9112 2068436 IFLab1_005567 NC(=O)c1ccsc1NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N02 compound treatment 0.312 -0.0151 -0.59 0.311 -0.0145 -0.3 -0.6333 -0.9517 2068437 IFLab1_005568 CC(=O)Nc1nnc(o1)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N03 compound treatment 0.372 0.0449 1.77 0.347 0.0215 0.45 1.5675 0.8597 2068438 IFLab1_005569 NC(=O)c1ccsc1NC(=O)c2ccc3OCCOc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N04 compound treatment 0.331 0.00394 0.15 0.323 -0.0025 -0.05 0.0725 0.4435 2068439 IFLab1_005570 CCn1c(=NC(=O)c2cccs2)sc3cc(Cl)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N05 compound treatment 0.33 0.00294 0.12 0.325 -5.0E-4 -0.01 0.0743 0.6404 2068440 IFLab1_005571 CNC(=O)c1ccsc1NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N06 compound treatment 0.176 -0.151 -5.94 0.165 -0.161 -3.36 -6.5748 -0.9636 2068441 IFLab1_005572 COC(=O)c1c(sc2CC(C)CCc12)N3C(=O)C=CC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N07 compound treatment 0.353 0.0259 1.02 0.342 0.0165 0.35 0.9653 0.8965 2068442 IFLab1_005573 COCCn1c(=NC(=O)/C=C/c2cccs2)sc3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N08 compound treatment 0.366 0.0389 1.53 0.368 0.0425 0.89 1.7114 0.9666 2068443 IFLab1_005574 O=C(CCOc1ccccc1)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N09 compound treatment 0.344 0.0169 0.67 0.345 0.0195 0.41 0.7594 0.9724 2068444 IFLab1_005575 CCN(CC)c1ccc(cc1)C(=O)N=c2sc3cc(OC)ccc3n2CCOC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N10 compound treatment 0.337 0.00994 0.39 0.336 0.0105 0.22 0.4317 0.9629 2068445 IFLab1_005576 CCCC(=O)Nc1sccc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N11 compound treatment 0.356 0.0289 1.14 0.354 0.0285 0.6 1.2262 0.9546 2068446 IFLab1_005577 FC(F)(F)c1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N12 compound treatment 0.344 0.0169 0.67 0.339 0.0135 0.28 0.6707 0.9271 2068447 IFLab1_005578 Cc1ccc(c(C)c1)n2ncc3c(O)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N13 compound treatment 0.371 0.0439 1.73 0.362 0.0365 0.76 1.7616 0.9327 2068448 IFLab1_005579 NS(=O)(=O)c1ccc2n(CC=C)c(=NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N14 compound treatment 0.348 0.0209 0.82 0.347 0.0215 0.45 0.9002 0.9596 2068449 IFLab1_005580 COc1ccccc1C(=O)NCCn2cc(SC(=N)N)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N15 compound treatment 0.335 0.00794 0.31 0.334 0.0085 0.18 0.3465 0.9645 1867574 IFLab1_005581 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCN(Cc4ccccc4)CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N16 compound treatment 0.348 0.0209 0.82 0.347 0.0215 0.45 0.9002 0.9596 2068450 IFLab1_005582 Nc1nc(cs1)c2ccc(C#N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N17 compound treatment 0.34 0.0129 0.51 0.338 0.0125 0.26 0.5447 0.9522 2068451 IFLab1_005583 Clc1ccc(s1)S(=O)(=O)NC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N18 compound treatment 0.34 0.0129 0.51 0.34 0.0145 0.3 0.5742 0.9695 1725012 IFLab1_005584 CC(=O)Nc1ccccc1OCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N19 compound treatment 0.335 0.00794 0.31 0.337 0.0115 0.24 0.3908 0.9918 2068452 IFLab1_005585 Clc1ccc(cc1)c2nnc(NC(=O)c3ccco3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N20 compound treatment 0.342 0.0149 0.59 0.339 0.0135 0.28 0.6151 0.9437 2068453 IFLab1_005586 CCOC(=O)c1cc(C(=O)N)c(SCC=C)[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N21 compound treatment 0.345 0.0179 0.71 0.351 0.0255 0.53 0.876 0.9905 2068454 IFLab1_005587 Cc1ccc(cc1C)C(=O)Nc2nnc(o2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N22 compound treatment 0.337 0.00994 0.39 0.336 0.0105 0.22 0.4317 0.9629 2068455 IFLab1_005588 Cc1sc(NC(=O)c2ccco2)c(C(N3CCOCC3)c4ccncc4)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N23 mock treatment 0.334 0.00694 0.27 0.331 0.0055 0.12 0.2743 0.9264 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 N24 positive control 0.093 -0.234 -9.2 0.091 -0.234 -4.91 -9.9773 -0.9566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O01 compound treatment 0.319 -0.00806 -0.32 0.316 -0.0095 -0.2 -0.3647 -0.9747 2068456 IFLab1_005589 COc1ccc(Cl)cc1NC(=O)CC(NCCc2ccccc2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O02 compound treatment 0.311 -0.0161 -0.63 0.31 -0.0155 -0.32 -0.6759 -0.952 2068457 IFLab1_005590 O=C(N1CCN(CC1)c2nc3ccccc3s2)C4=COCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O03 compound treatment 0.306 -0.0211 -0.83 0.305 -0.0205 -0.43 -0.8889 -0.9531 2068458 IFLab1_005591 Cn1c(SCC(=O)c2ccccc2)nnc1c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O04 compound treatment 0.314 -0.0131 -0.51 0.314 -0.0115 -0.24 -0.5333 -0.9403 2068459 IFLab1_005592 NC(=O)c1c(NC(=O)C2=COCCO2)sc3CCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O05 compound treatment 0.309 -0.0181 -0.71 0.308 -0.0175 -0.37 -0.7611 -0.9525 1306646 IFLab1_005593 CCC(=O)OC1CCC2C3CCC4CC(=O)CCC4(C)C3CCC12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O06 compound treatment 0.316 -0.0111 -0.43 0.318 -0.0075 -0.16 -0.4185 -0.9051 2068460 IFLab1_005594 Cc1cc(NC(=O)c2ccc(s2)c3nc4ccccc4s3)no1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O07 compound treatment 0.316 -0.0111 -0.43 0.315 -0.0105 -0.22 -0.4629 -0.95 2068461 IFLab1_005595 Cc1nnc(SCC(=O)O)n1/N=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O08 compound treatment 0.329 0.00194 0.08 0.335 0.0095 0.2 0.1944 0.9133 1616098 IFLab1_005596 CCN(CC)c1ccc2nc(C)c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O09 compound treatment 0.317 -0.0101 -0.4 0.318 -0.0075 -0.16 -0.3907 -0.918 1873681 IFLab1_005597 CC(=O)Nc1ccc(OCC(O)CN2CCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O10 compound treatment 0.325 -0.00206 -0.08 0.327 0.0015 0.03 -0.0351 -0.4042 2068462 IFLab1_005598 CN1CCN(CC1)C(=O)c2cc3ccccc3nc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O11 compound treatment 0.36 0.0329 1.3 0.359 0.0335 0.7 1.4114 0.9585 2068463 IFLab1_005599 Cc1ccc(cc1)c2csc(NC3OC(=O)c4ccccc34)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O12 compound treatment 0.345 0.0179 0.71 0.345 0.0195 0.41 0.7872 0.9662 2068464 IFLab1_005600 COC(=O)c1ccccc1NC(=O)CSc2nc3ccccc3nc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O13 compound treatment 0.334 0.00694 0.27 0.337 0.0115 0.24 0.363 0.998 2068465 IFLab1_005601 COC(=O)c1c(NC(=O)c2ccc(Cl)s2)sc3CN(CCc13)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O14 compound treatment 0.362 0.0349 1.37 0.356 0.0305 0.64 1.4226 0.9392 2068466 IFLab1_005602 FC(F)(F)c1ccccc1NC2=NC(=O)CS2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O15 compound treatment 0.37 0.0429 1.69 0.407 0.0815 1.71 2.3997 1.0 2068467 IFLab1_005603 COC(=O)c1ccc2nc(NC(=O)CCOc3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O16 compound treatment 0.337 0.00994 0.39 0.335 0.0095 0.2 0.4169 0.9509 2068468 IFLab1_005604 COC(=O)CSc1nnc(o1)c2ccc(OC)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O17 compound treatment 0.349 0.0219 0.86 0.348 0.0225 0.47 0.9428 0.9595 2068469 IFLab1_005605 CC(C)C(=O)Nc1nc2c(C)c(C)ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O18 compound treatment 0.342 0.0149 0.59 0.341 0.0155 0.32 0.6446 0.9608 1446160 IFLab1_005606 CC1CCN(CC(O)Cn2c3ccccc3c4ccccc24)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O19 compound treatment 0.333 0.00594 0.23 0.332 0.0065 0.14 0.2613 0.9669 2068470 IFLab1_005607 O=C(Nc1nc2ccccc2s1)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O20 compound treatment 0.34 0.0129 0.51 0.336 0.0105 0.22 0.5151 0.9295 2068471 IFLab1_005608 CNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O21 compound treatment 0.342 0.0149 0.59 0.339 0.0135 0.28 0.6151 0.9437 2068472 IFLab1_005609 O=C(Nc1sc2CCCCc2c1C#N)C3=COCCO3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O22 compound treatment 0.34 0.0129 0.51 0.341 0.0155 0.32 0.589 0.9764 2068473 IFLab1_005610 COC(=O)c1ccsc1NC(=O)CCOc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O23 mock treatment 0.331 0.00394 0.15 0.331 0.0055 0.12 0.1909 0.9893 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 O24 positive control 0.094 -0.233 -9.16 0.095 -0.231 -4.82 -9.8903 -0.9551 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P01 compound treatment 0.363 0.0359 1.41 0.359 0.0335 0.7 1.4948 0.9477 2068474 IFLab1_005611 COc1ccc(C(=O)Nc2sccc2C(=O)N)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P02 compound treatment 0.327 -6.25E-5 0.0 0.322 -0.0035 -0.07 -0.0535 -0.7304 2068475 IFLab1_005612 O=C(Nc1nnc(o1)c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P03 compound treatment 0.361 0.0339 1.33 0.354 0.0285 0.6 1.3652 0.9341 2068476 IFLab1_005613 NC(=O)c1ccsc1NC(=O)c2ccc3CCCCc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P04 compound treatment 0.348 0.0209 0.82 0.35 0.0245 0.51 0.9446 0.974 2068477 IFLab1_005614 CCn1c(=NC(=O)C2CC2)sc3cc(Cl)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P05 compound treatment 0.376 0.0489 1.92 0.366 0.0405 0.85 1.9598 0.9321 2068478 IFLab1_005615 CNC(=O)c1ccsc1NC(=O)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P06 compound treatment 0.365 0.0379 1.49 0.356 0.0305 0.64 1.5061 0.9283 2068479 IFLab1_005616 O=C(Nc1sccc1C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P07 compound treatment 0.361 0.0339 1.33 0.357 0.0315 0.66 1.4096 0.9472 2068480 IFLab1_005617 COCCn1c(=NC(=O)C)sc2cc(ccc12)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P08 compound treatment 0.36 0.0329 1.3 0.361 0.0355 0.74 1.441 0.9652 2068481 IFLab1_005618 COC(=O)c1ccc(cc1)C(=O)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P09 compound treatment 0.367 0.0399 1.57 0.367 0.0415 0.87 1.7244 0.961 2068482 IFLab1_005619 OC(=O)CCNS(=O)(=O)c1cccc(c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P10 compound treatment 0.365 0.0379 1.49 0.382 0.0565 1.18 1.8908 0.9934 2068483 IFLab1_005620 O=C(CCc1ccccc1)Nc2sccc2C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P11 compound treatment 0.36 0.0329 1.3 0.359 0.0335 0.7 1.4114 0.9585 2068484 IFLab1_005621 CC(C)(C)NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P12 compound treatment 0.356 0.0289 1.14 0.356 0.0305 0.64 1.2558 0.9626 1199381 IFLab1_005622 Cc1ccccc1c2nnc(N)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P13 compound treatment 0.441 0.114 4.48 0.441 0.116 2.42 4.8768 0.9581 2068485 IFLab1_005623 NS(=O)(=O)c1ccc2n(CC=C)c(=NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P14 compound treatment 0.36 0.0329 1.3 0.35 0.0245 0.51 1.2783 0.9177 2068486 IFLab1_005624 Cc1nn(c(O)c1Sc2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P15 compound treatment 0.348 0.0209 0.82 0.342 0.0165 0.35 0.8263 0.9256 1175473 IFLab1_005625 CC(=O)N1CCc2ccccc2C1CC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P16 compound treatment 0.353 0.0259 1.02 0.343 0.0175 0.37 0.9801 0.9045 1719186 IFLab1_005626 Nc1nc2ccc(cc2s1)S(=O)(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P17 compound treatment 0.354 0.0269 1.06 0.354 0.0285 0.6 1.1706 0.9631 2068487 IFLab1_005627 O=C(NS(=O)(=O)c1ccc2OCCOc2c1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P18 compound treatment 0.38 0.0529 2.08 0.376 0.0505 1.06 2.219 0.9506 2068488 IFLab1_005628 CSC(C)C(=O)C1=C(O)c2ccccc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P19 compound treatment 0.357 0.0299 1.18 0.347 0.0215 0.45 1.1505 0.913 2068489 IFLab1_005629 Clc1ccc(cc1)c2nnc(NC(=O)CCOc3ccccc3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P20 compound treatment 0.363 0.0359 1.41 0.353 0.0275 0.58 1.4061 0.9216 2068490 IFLab1_005630 C=CCn1c2ccccc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P21 compound treatment 0.354 0.0269 1.06 0.351 0.0255 0.53 1.1262 0.9496 2068491 IFLab1_005631 Clc1c(sc2ccccc12)C(=O)Nc3nnc(o3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P22 compound treatment 0.35 0.0229 0.9 0.351 0.0255 0.53 1.015 0.9686 2068492 IFLab1_005632 Cc1sc(NC(=O)c2ccco2)c(CN3CCN(CC3)c4ccccn4)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P23 mock treatment 0.341 0.0139 0.55 0.332 0.0065 0.14 0.4837 0.8566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1427 P24 positive control 0.098 -0.229 -9.01 0.098 -0.228 -4.76 -9.7347 -0.9556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A01 compound treatment 0.333 0.00825 0.32 0.33 0.0075 0.16 0.3403 0.9445 2068493 IFLab1_005633 Cc1sc(NC(=O)c2ccco2)c(CN3CCc4ccccc4C3)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A02 compound treatment 0.313 -0.0118 -0.46 0.314 -0.0085 -0.18 -0.4524 -0.914 1875154 IFLab1_005634 CC(Oc1ccc(F)cc1)C(=O)Nc2ccccc2Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A03 compound treatment 0.322 -0.00275 -0.11 0.309 -0.0135 -0.28 -0.2762 -0.9131 2068494 IFLab1_005635 Fc1cccc(/C=C/C(=O)Nc2ccon2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A04 compound treatment 0.313 -0.0118 -0.46 0.315 -0.0075 -0.16 -0.4377 -0.897 2068495 IFLab1_005636 CCN1C(=O)/C(=C/2\SC(=S)N(C3CCCC3)C2=O)/c4cc(Br)ccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A05 compound treatment 0.338 0.0133 0.52 0.31 -0.0125 -0.26 0.1834 0.3146 2068496 IFLab1_005637 Cc1ccc(o1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A06 compound treatment 0.314 -0.0107 -0.42 0.356 0.0335 0.7 0.1968 0.2405 2068497 IFLab1_005638 Cc1ccc(cc1)c2nc3sc(=Cc4cccs4)c(=O)n3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A07 compound treatment 0.314 -0.0107 -0.42 0.324 0.0015 0.03 -0.2767 -0.6528 1873189 IFLab1_005639 CC(C)c1cc(NCCN(C)C)n2c3ccccc3nc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A08 compound treatment 0.31 -0.0147 -0.58 0.32 -0.0025 -0.05 -0.4471 -0.7678 2068498 IFLab1_005640 CCSc1nnc(c2ccco2)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A09 compound treatment 0.338 0.0133 0.52 0.32 -0.0025 -0.05 0.3314 0.6329 2068499 IFLab1_005641 CCC(C)Nc1ncnc2n(Cc3ccc(Cl)cc3)ncc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A10 compound treatment 0.317 -0.00775 -0.3 0.356 0.0335 0.7 0.2802 0.3666 2068500 IFLab1_005642 FC(F)(F)c1ccccc1NC(=O)CSc2nc3sc4CCCc4c3c(=O)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A11 compound treatment 0.326 0.00125 0.05 0.325 0.0025 0.05 0.0717 0.9995 2068501 IFLab1_005643 Cc1ccc(cc1C)N2CCN(CC2)C(=O)c3ccc(Br)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A12 compound treatment 0.333 0.00825 0.32 0.336 0.0135 0.28 0.4291 0.9976 2068502 IFLab1_005644 CCOc1ccccc1Cn2c(=O)oc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A13 compound treatment 0.317 -0.00775 -0.3 0.348 0.0255 0.53 0.1619 0.2634 2068503 IFLab1_005645 COc1ccc(cc1OC)C2=N/C(=C/c3cccnc3)/C(=O)O2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A14 compound treatment 0.341 0.0163 0.64 0.322 -5.0E-4 -0.01 0.4444 0.6954 2068504 IFLab1_005646 Cc1cccc(OCC(O)CN2CCc3ccccc3C2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A15 compound treatment 0.318 -0.00675 -0.27 0.323 5.0E-4 0.01 -0.1803 -0.6787 2068505 IFLab1_005647 CN(C)C(=O)CSc1nc(nc2CCCCc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A16 compound treatment 0.315 -0.00975 -0.38 0.338 0.0155 0.32 -0.0417 -0.0831 2068506 IFLab1_005648 OC(COc1ccccc1Br)CN2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A17 compound treatment 0.327 0.00225 0.09 0.326 0.0035 0.07 0.1143 0.9956 2068507 IFLab1_005649 CCNc1c2-c3ccccc3C(=O)c4cccc(n(C)c1=O)c42 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A18 compound treatment 0.344 0.0193 0.76 0.321 -0.0015 -0.03 0.513 0.6772 2068508 IFLab1_005650 CCN1CCN(CCC(=O)Nc2sc3CCCCCc3c2C#N)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A19 compound treatment 0.313 -0.0118 -0.46 0.321 -0.0015 -0.03 -0.3489 -0.7534 2068509 IFLab1_005651 CCCC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A20 compound treatment 0.322 -0.00275 -0.11 0.347 0.0245 0.51 0.2861 0.546 2068510 IFLab1_005652 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A21 compound treatment 0.319 -0.00575 -0.23 0.322 -5.0E-4 -0.01 -0.1673 -0.739 2068511 IFLab1_005653 O=C(Nc1nc2ccc(cc2s1)S(=O)(=O)N3CCCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A22 compound treatment 0.316 -0.00875 -0.34 0.318 -0.0045 -0.09 -0.3099 -0.8687 2068512 IFLab1_005654 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(Oc3ccccc3C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A23 mock treatment 0.349 0.0243 0.95 0.316 -0.0065 -0.14 0.578 0.6002 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 A24 positive control 0.081 -0.244 -9.58 0.079 -0.243 -5.1 -10.3798 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B01 compound treatment 0.335 0.0103 0.4 0.338 0.0155 0.32 0.5143 0.9942 2068513 IFLab1_005655 Cc1nnc(SCC(=O)NCc2ccc3OCOc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B02 compound treatment 0.322 -0.00275 -0.11 0.324 0.0015 0.03 -0.0543 -0.4819 2068514 IFLab1_005656 COc1cccc2cc(C(=O)NCCc3c(C)[nH]c4c(C)cccc34)c(=O)oc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B03 compound treatment 0.34 0.0153 0.6 0.347 0.0245 0.51 0.7865 0.997 1438875 IFLab1_005657 Cc1sc(NC(=O)C(c2ccccc2)c3ccccc3)c(C(=O)N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B04 compound treatment 0.329 0.00425 0.17 0.331 0.0085 0.18 0.2439 0.9995 2068515 IFLab1_005658 COc1ccc(cc1C)S(=O)(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B05 compound treatment 0.309 -0.0158 -0.62 0.309 -0.0135 -0.28 -0.6376 -0.9368 2068516 IFLab1_005659 Cn1cc(C(=O)Cc2ccccc2)c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B06 compound treatment 0.316 -0.00875 -0.34 0.329 0.0065 0.14 -0.1471 -0.3976 2068517 IFLab1_005660 Cc1ccc(cc1)C(=O)COC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B07 compound treatment 0.34 0.0153 0.6 0.346 0.0235 0.49 0.7717 0.9952 2068518 IFLab1_005661 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCCCC2)/C=C/c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B08 compound treatment 0.322 -0.00275 -0.11 0.308 -0.0145 -0.3 -0.291 -0.9034 2068519 IFLab1_005662 Cc1cccc(c1)N2C(=O)CC(Sc3ncccc3C(=O)O)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B09 compound treatment 0.327 0.00225 0.09 0.331 0.0085 0.18 0.1883 0.948 1480619 IFLab1_005663 Cc1cc(Br)ccc1OCC(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B10 compound treatment 0.322 -0.00275 -0.11 0.329 0.0065 0.14 0.0197 0.1135 2068520 IFLab1_005664 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B11 compound treatment 0.339 0.0143 0.56 0.331 0.0085 0.18 0.522 0.8879 2068521 IFLab1_005665 Cc1ccc(/C=C/C(=O)N2CCCc3ccccc23)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B12 compound treatment 0.334 0.00925 0.36 0.357 0.0345 0.72 0.7677 0.9496 2068522 IFLab1_005666 CN1C(=O)/C(=C/c2c[nH]c3ccccc23)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B13 compound treatment 0.324 -7.5E-4 -0.03 0.326 0.0035 0.07 0.0309 0.3918 1860959 IFLab1_005667 CCC(=O)Nc1ccc(cc1)C(=O)n2ccc(C)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B14 compound treatment 0.33 0.00525 0.21 0.342 0.0195 0.41 0.4345 0.9502 2068523 IFLab1_005668 O=C(Nc1ccccc1)c2cc3ccccc3c(=O)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B15 compound treatment 0.325 2.5E-4 0.01 0.336 0.0135 0.28 0.2067 0.7313 1172781 IFLab1_005669 C(NCc1ccccc1)C2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B16 compound treatment 0.336 0.0113 0.44 0.33 0.0075 0.16 0.4238 0.9029 1295216 IFLab1_005670 COc1ccc(cc1)C(=O)N2CCn3c2nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B17 compound treatment 0.321 -0.00375 -0.15 0.339 0.0165 0.35 0.1399 0.3726 1983615 IFLab1_005671 COC(=O)CCC(=O)N1CCc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B18 compound treatment 0.328 0.00325 0.13 0.331 0.0085 0.18 0.2161 0.9868 2068524 IFLab1_005672 O=C(Nc1ccc2[nH]c3CCCCc3c2c1)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B19 compound treatment 0.332 0.00725 0.29 0.335 0.0125 0.26 0.3865 0.9991 1183336 IFLab1_005673 O=C(COc1ccccc1)Nc2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B20 compound treatment 0.341 0.0163 0.64 0.339 0.0165 0.35 0.6959 0.9583 2068525 IFLab1_005674 CN1CCN(CC1)C(c2c(C)c(C)sc2NC(=O)c3ccco3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B21 compound treatment 0.339 0.0143 0.56 0.338 0.0155 0.32 0.6255 0.9662 1726674 IFLab1_005675 COC(=O)CCC(=O)Nc1sc2CCCCc2c1C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B22 compound treatment 0.329 0.00425 0.17 0.331 0.0085 0.18 0.2439 0.9995 2068526 IFLab1_005676 COc1cc(c(OC)cc1Cl)S(=O)(=O)N(C)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B23 mock treatment 0.326 0.00125 0.05 0.325 0.0025 0.05 0.0717 0.9995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 B24 positive control 0.079 -0.246 -9.66 0.078 -0.245 -5.12 -10.4502 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C01 compound treatment 0.329 0.00425 0.17 0.329 0.0065 0.14 0.2143 0.9948 1530278 IFLab1_005677 O=c1oc(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C02 compound treatment 0.33 0.00525 0.21 0.337 0.0145 0.3 0.3605 0.9824 2068527 IFLab1_005678 CCCN1C(=O)/C(=C/2\SC(=S)NC2=O)/c3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C03 compound treatment 0.322 -0.00275 -0.11 0.335 0.0125 0.26 0.1085 0.3834 2068528 IFLab1_005679 O=C1CC(SC(=N1)N2CCc3ccccc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C04 compound treatment 0.352 0.0273 1.07 0.339 0.0165 0.35 1.0018 0.8899 2068529 IFLab1_005680 CCN1C(=O)/C(=C/2\SC(=S)NC2=O)/c3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C05 compound treatment 0.317 -0.00775 -0.3 0.329 0.0065 0.14 -0.1193 -0.3575 2068530 IFLab1_005681 COc1ccc(cc1O)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C06 compound treatment 0.344 0.0193 0.76 0.33 0.0075 0.16 0.6462 0.836 2068531 IFLab1_005682 CCC1CCCCN1S(=O)(=O)c2ccc(NC(=O)/C=C/c3ccco3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C07 compound treatment 0.321 -0.00375 -0.15 0.315 -0.0075 -0.16 -0.2152 -0.9995 1873195 IFLab1_005683 CC(C)c1cc(NCCN2CCOCC2)n3c4ccccc4nc3c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C08 compound treatment 0.327 0.00225 0.09 0.338 0.0155 0.32 0.2919 0.8682 2068532 IFLab1_005684 Cc1ccsc1C=c2sc3nc(nn3c2=O)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C09 compound treatment 0.324 -7.5E-4 -0.03 0.336 0.0135 0.28 0.1789 0.6299 2068533 IFLab1_005685 Cc1ccc(Cn2ncc3c(ncnc23)N4CCOCC4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C10 compound treatment 0.335 0.0103 0.4 0.335 0.0125 0.26 0.4699 0.9781 1650368 IFLab1_005686 Cc1ccc(cc1)S(=O)(=O)c2nc(NC3CCS(=O)(=O)C3)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C11 compound treatment 0.334 0.00925 0.36 0.333 0.0105 0.22 0.4125 0.9709 2068534 IFLab1_005687 CCOc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C12 compound treatment 0.326 0.00125 0.05 0.322 -5.0E-4 -0.01 0.0274 0.5444 2068535 IFLab1_005688 O=c1oc2ccccc2n1CCCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C13 compound treatment 0.333 0.00825 0.32 0.333 0.0105 0.22 0.3847 0.982 2068536 IFLab1_005689 CC1CN(CC(C)O1)S(=O)(=O)CC2(CCC3CC2=O)C3(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C14 compound treatment 0.332 0.00725 0.29 0.333 0.0105 0.22 0.3569 0.9917 2068537 IFLab1_005690 Cc1cccc(OCC(O)CN2C(C)(C)CC(O)CC2(C)C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C15 compound treatment 0.321 -0.00375 -0.15 0.331 0.0085 0.18 0.0215 0.0931 2068538 IFLab1_005691 O=C(CSc1nc(nc2CCCCc12)c3ccccc3)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C16 compound treatment 0.332 0.00725 0.29 0.327 0.0045 0.09 0.2682 0.8932 2068539 IFLab1_005692 CC1(C)CCCC(C)(C)N1CC(O)COc2ccccc2Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C17 compound treatment 0.337 0.0123 0.48 0.332 0.0095 0.2 0.4811 0.9234 1204795 IFLab1_005693 CNc1c2-c3ccccc3C(=O)c4cccc(n(C)c1=O)c42 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C18 compound treatment 0.32 -0.00475 -0.19 0.331 0.0085 0.18 -0.0063 -0.0244 1592072 IFLab1_005694 Cc1nc(N2CCCC2)c3ccsc3n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C19 compound treatment 0.322 -0.00275 -0.11 0.322 -5.0E-4 -0.01 -0.0839 -0.7719 2068540 IFLab1_005695 CN(C)S(=O)(=O)c1ccc2nc(NC(=O)/C=C/c3ccccc3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C20 compound treatment 0.327 0.00225 0.09 0.335 0.0125 0.26 0.2475 0.8964 2068541 IFLab1_005696 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C21 compound treatment 0.333 0.00825 0.32 0.331 0.0085 0.18 0.3551 0.96 1193718 IFLab1_005697 OC(=O)CCN1C(=O)C2C3CC(C=C3)C2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C22 compound treatment 0.334 0.00925 0.36 0.333 0.0105 0.22 0.4125 0.9709 2068542 IFLab1_005698 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C23 mock treatment 0.321 -0.00375 -0.15 0.328 0.0055 0.12 -0.0229 -0.1223 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 C24 positive control 0.079 -0.246 -9.66 0.079 -0.243 -5.1 -10.4354 -0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D01 compound treatment 0.336 0.0113 0.44 0.333 0.0105 0.22 0.4681 0.9479 2068543 IFLab1_005699 CCOC(=O)c1c(NC(=O)CSc2nnc(C)s2)sc3CCCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D02 compound treatment 0.315 -0.00975 -0.38 0.329 0.0065 0.14 -0.1749 -0.4299 2068544 IFLab1_005700 COc1ccc(cc1)C(=O)C(C)OC(=O)c2cc(C)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D03 compound treatment 0.32 -0.00475 -0.19 0.32 -0.0025 -0.05 -0.1691 -0.8716 2068545 IFLab1_005701 CCOC(=O)c1c(NC(=O)COc2ccccc2OC)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D04 compound treatment 0.315 -0.00975 -0.38 0.325 0.0025 0.05 -0.2341 -0.605 2068546 IFLab1_005702 COc1cc(C)c(cc1C)S(=O)(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D05 compound treatment 0.32 -0.00475 -0.19 0.329 0.0065 0.14 -0.0359 -0.1553 1984307 IFLab1_005703 CNCCn1ccc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D06 compound treatment 0.329 0.00425 0.17 0.331 0.0085 0.18 0.2439 0.9995 2068547 IFLab1_005704 CC(OC(=O)c1cc2ccccc2oc1=O)C(=O)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D07 compound treatment 0.317 -0.00775 -0.3 0.332 0.0095 0.2 -0.0749 -0.2058 2068548 IFLab1_005705 CN(C(=O)C)c1ccc(NC(=O)/C=C/c2ccco2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D08 compound treatment 0.33 0.00525 0.21 0.339 0.0165 0.35 0.3901 0.9698 2068549 IFLab1_005706 CCOc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D09 compound treatment 0.32 -0.00475 -0.19 0.336 0.0135 0.28 0.0677 0.1999 1587778 IFLab1_005707 Cc1cc(C)n(n1)C(=O)c2ccc(NC(=O)C3CCCCC3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D10 compound treatment 0.343 0.0182 0.72 0.339 0.0165 0.35 0.7515 0.9438 2068550 IFLab1_005708 Cc1nc(cs1)c2ccc(NS(=O)(=O)C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D11 compound treatment 0.371 0.0462 1.82 0.352 0.0295 0.62 1.7224 0.8969 2068551 IFLab1_005709 CCOC(=O)c1ccc(NC(=O)/C=C/c2ccc(C)o2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D12 compound treatment 0.32 -0.00475 -0.19 0.335 0.0125 0.26 0.0529 0.1646 1727105 IFLab1_005710 Cc1cc(C)c(cc1C)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D13 compound treatment 0.329 0.00425 0.17 0.327 0.0045 0.09 0.1847 0.9632 1860982 IFLab1_005711 Cc1ccn(n1)C(=O)c2ccc(NC(=O)C3CC3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D14 compound treatment 0.325 2.5E-4 0.01 0.324 0.0015 0.03 0.0291 0.8861 2068552 IFLab1_005712 CCOC(=O)c1ccc(NC(=O)c2cc3ccccc3c(=O)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D15 compound treatment 0.331 0.00625 0.25 0.333 0.0105 0.22 0.3291 0.9984 2068553 IFLab1_005713 Cc1cc([nH]n1)C(=O)n2nc(C)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D16 compound treatment 0.347 0.0222 0.87 0.332 0.0095 0.2 0.7592 0.8462 1527441 IFLab1_005714 O=C(N1CCn2c1nc3ccccc23)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D17 compound treatment 0.324 -7.5E-4 -0.03 0.335 0.0125 0.26 0.1641 0.6234 2068554 IFLab1_005715 CC(=O)N/C(=C\c1ccccc1)/C(=O)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D18 compound treatment 0.336 0.0113 0.44 0.333 0.0105 0.22 0.4681 0.9479 2068555 IFLab1_005716 O=C(Nc1ccc2[nH]c3CCCCc3c2c1)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D19 compound treatment 0.34 0.0153 0.6 0.338 0.0155 0.32 0.6533 0.9584 1515305 IFLab1_005717 COC(=O)CCC(=O)Nc1nc(cs1)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D20 compound treatment 0.34 0.0153 0.6 0.336 0.0135 0.28 0.6237 0.941 2068556 IFLab1_005718 CC1(C)CC(CC(C)(C)N1)NS(=O)(=O)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D21 compound treatment 0.335 0.0103 0.4 0.333 0.0105 0.22 0.4403 0.9593 1351356 IFLab1_005719 Cc1ccc(OCC(=O)N2CCCc3ccccc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D22 compound treatment 0.33 0.00525 0.21 0.329 0.0065 0.14 0.2421 0.9795 2068557 IFLab1_005720 COc1ccc(c(C)c1C)S(=O)(=O)N2CCN(C)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D23 mock treatment 0.325 2.5E-4 0.01 0.324 0.0015 0.03 0.0291 0.8861 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 D24 positive control 0.08 -0.245 -9.62 0.08 -0.242 -5.07 -10.3928 -0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E01 compound treatment 0.331 0.00625 0.25 0.336 0.0135 0.28 0.3735 0.9976 2068558 IFLab1_005721 COC(=O)c1ccc(/C=N/n2cnnc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E02 compound treatment 0.314 -0.0107 -0.42 0.328 0.0055 0.12 -0.2175 -0.4965 2068559 IFLab1_005722 Oc1nc(cc(n1)C(F)(F)F)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E03 compound treatment 0.321 -0.00375 -0.15 0.331 0.0085 0.18 0.0215 0.0931 2068560 IFLab1_005723 O=C(N1CCc2ccccc12)c3ccc(cc3)S(=O)(=O)NCC4CCCO4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E04 compound treatment 0.376 0.0512 2.02 0.379 0.0565 1.18 2.2609 0.9677 2068561 IFLab1_005724 CC(C)N1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E05 compound treatment 0.321 -0.00375 -0.15 0.329 0.0065 0.14 -0.0081 -0.0403 2068562 IFLab1_005725 O=C1CCCC2=C1C(C3=C(CCCC3=O)O2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E06 compound treatment 0.317 -0.00775 -0.3 0.329 0.0065 0.14 -0.1193 -0.3575 2068563 IFLab1_005726 CC(C)Oc1ccc(cc1)C(=O)NC2CCS(=O)(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E07 compound treatment 0.322 -0.00275 -0.11 0.336 0.0135 0.28 0.1233 0.4076 1016316 IFLab1_005727 Oc1ncnc2n(Cc3ccccc3)ncc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E08 compound treatment 0.344 0.0193 0.76 0.347 0.0245 0.51 0.8977 0.982 2068564 IFLab1_005728 CC(=O)Nc1c(nc2ncccn12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E09 compound treatment 0.364 0.0393 1.54 0.388 0.0655 1.37 2.0604 0.9983 2068565 IFLab1_005729 Cc1ccc(Cn2ncc3c(Nc4ccc(C)cc4)ncnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E10 compound treatment 0.364 0.0393 1.54 0.346 0.0235 0.49 1.439 0.8884 1470713 IFLab1_005730 Cc1ccc(cc1)S(=O)(=O)c2nc(NN)sc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E11 compound treatment 0.333 0.00825 0.32 0.339 0.0165 0.35 0.4735 0.9995 1264560 IFLab1_005731 COC(=O)c1cc(Br)ccc1NC(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E12 compound treatment 0.332 0.00725 0.29 0.331 0.0085 0.18 0.3273 0.9742 1050406 IFLab1_005732 Cc1cccc(OCC(O)CN2CCCCC2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E13 compound treatment 0.34 0.0153 0.6 0.336 0.0135 0.28 0.6237 0.941 2068566 IFLab1_005733 CC(C)(C)N/C(=N/S(=O)(=O)c1cccs1)/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E14 compound treatment 0.333 0.00825 0.32 0.336 0.0135 0.28 0.4291 0.9976 1051147 IFLab1_005734 Cc1cccc(OCC(O)CN2CCN(CC2)c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E15 compound treatment 0.343 0.0182 0.72 0.34 0.0175 0.37 0.7663 0.9513 2068567 IFLab1_005735 FC(F)(F)c1ccc2SC(CC(=O)NC3CCCCC3)C(=O)Nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E16 compound treatment 0.337 0.0123 0.48 0.334 0.0115 0.24 0.5107 0.9486 2068568 IFLab1_005736 COc1ccc2c(Cl)c(sc2c1)c3nnc(SCC(=O)N)n3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E17 compound treatment 0.335 0.0103 0.4 0.336 0.0135 0.28 0.4847 0.9849 1229014 IFLab1_005737 CCOC(=O)c1c2-c3ccccc3C(=O)c4cccc([nH]c1=O)c42 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E18 compound treatment 0.325 2.5E-4 0.01 0.329 0.0065 0.14 0.1031 0.7562 1465443 IFLab1_005738 COC(=O)c1c(N)sc2CCCCCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E19 compound treatment 0.333 0.00825 0.32 0.334 0.0115 0.24 0.3995 0.9892 2068569 IFLab1_005739 CN(C)S(=O)(=O)c1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E20 compound treatment 0.339 0.0143 0.56 0.338 0.0155 0.32 0.6255 0.9662 2068570 IFLab1_005740 COc1cccc(c1)S(=O)(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E21 compound treatment 0.341 0.0163 0.64 0.34 0.0175 0.37 0.7107 0.9651 2068571 IFLab1_005741 COC(=O)C1Sc2[nH]c(=O)sc2C(C1C(=O)OC)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E22 compound treatment 0.327 0.00225 0.09 0.326 0.0035 0.07 0.1143 0.9956 2068572 IFLab1_005742 CCN1CCN(CC1)S(=O)(=O)c2ccc(Oc3ccccc3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E23 mock treatment 0.32 -0.00475 -0.19 0.318 -0.0045 -0.09 -0.1986 -0.9497 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 E24 positive control 0.081 -0.244 -9.58 0.081 -0.241 -5.05 -10.3502 -0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F01 compound treatment 0.329 0.00425 0.17 0.33 0.0075 0.16 0.2291 0.9995 1258274 IFLab1_005743 Cc1nnc(SCC(=O)Nc2ccc3OCCOc3c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F02 compound treatment 0.316 -0.00875 -0.34 0.316 -0.0065 -0.14 -0.3394 -0.9176 2068573 IFLab1_005744 COc1ccc(cc1)C(=O)C(C)OC(=O)c2ccc3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F03 compound treatment 0.321 -0.00375 -0.15 0.325 0.0025 0.05 -0.0673 -0.4299 1243591 IFLab1_005745 O=C(Cc1ccccc1)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F04 compound treatment 0.325 2.5E-4 0.01 0.329 0.0065 0.14 0.1031 0.7562 2068574 IFLab1_005746 COc1cc(Cl)ccc1S(=O)(=O)N2CCN(CC2)c3ccc(C)c(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F05 compound treatment 0.311 -0.0138 -0.54 0.307 -0.0155 -0.32 -0.6116 -0.9701 1223953 IFLab1_005747 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCCC2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F06 compound treatment 0.331 0.00625 0.25 0.326 0.0035 0.07 0.2256 0.8796 2068575 IFLab1_005748 CCC(=O)c1ccc(OC(=O)c2cc3cc(Br)ccc3oc2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F07 compound treatment 0.328 0.00325 0.13 0.34 0.0175 0.37 0.3493 0.9006 2068576 IFLab1_005749 O=C(Nc1ccc(Oc2ccccc2)cc1)/C=C/c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F08 compound treatment 0.336 0.0113 0.44 0.344 0.0215 0.45 0.6309 1.0 2068577 IFLab1_005750 CCOc1cc(ccc1OC)C(C#N)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F09 compound treatment 0.34 0.0153 0.6 0.331 0.0085 0.18 0.5498 0.879 2068578 IFLab1_005751 O=C(C1CC1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F10 compound treatment 0.325 2.5E-4 0.01 0.333 0.0105 0.22 0.1623 0.738 2068579 IFLab1_005752 Clc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F11 compound treatment 0.337 0.0123 0.48 0.331 0.0085 0.18 0.4663 0.9083 2068580 IFLab1_005753 O=C(/C=C/c1ccco1)N2CCCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F12 compound treatment 0.335 0.0103 0.4 0.334 0.0115 0.24 0.4551 0.9696 1372844 IFLab1_005754 Cc1cc(C)c(cc1C)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F13 compound treatment 0.342 0.0173 0.68 0.338 0.0155 0.32 0.7089 0.943 2068581 IFLab1_005755 O=C(C1CC1)N2CCNC(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F14 compound treatment 0.344 0.0193 0.76 0.346 0.0235 0.49 0.8829 0.9782 2068582 IFLab1_005756 COc1cccc(CC2(O)C(=O)Nc3ccccc32)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F15 compound treatment 0.341 0.0163 0.64 0.339 0.0165 0.35 0.6959 0.9583 2068583 IFLab1_005757 CC(C)(C)OC(=O)N1CCNC(=O)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F16 compound treatment 0.338 0.0133 0.52 0.347 0.0245 0.51 0.7309 1.0 2068584 IFLab1_005758 CS(=O)(=O)N1CCn2c1nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F17 compound treatment 0.37 0.0452 1.78 0.376 0.0535 1.12 2.0497 0.9751 1136002 IFLab1_005759 O=C(Nc1ccc(cc1)C(=O)c2ccccc2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F18 compound treatment 0.339 0.0143 0.56 0.339 0.0165 0.35 0.6403 0.973 2068585 IFLab1_005760 Cc1ccn2cc(CSc3ncccn3)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F19 compound treatment 0.324 -7.5E-4 -0.03 0.341 0.0185 0.39 0.2529 0.6514 1450947 IFLab1_005761 Cc1ccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F20 compound treatment 0.321 -0.00375 -0.15 0.332 0.0095 0.2 0.0363 0.1467 2068586 IFLab1_005762 CCOc1ccc(c2ccccc12)S(=O)(=O)NC3CC(C)(C)NC(C)(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F21 compound treatment 0.335 0.0103 0.4 0.321 -0.0015 -0.03 0.2628 0.6501 1520384 IFLab1_005763 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F22 compound treatment 0.335 0.0103 0.4 0.324 0.0015 0.03 0.3072 0.7599 2068587 IFLab1_005764 CCOc1ccc(Cl)cc1S(=O)(=O)N2CCCC(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F23 mock treatment 0.32 -0.00475 -0.19 0.325 0.0025 0.05 -0.0951 -0.4902 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 F24 positive control 0.082 -0.243 -9.54 0.081 -0.241 -5.05 -10.3224 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G01 compound treatment 0.328 0.00325 0.13 0.333 0.0105 0.22 0.2457 0.9667 1241260 IFLab1_005765 CCOC(=O)c1ccc(NC(=O)c2ccccc2OC(=O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G02 compound treatment 0.316 -0.00875 -0.34 0.319 -0.0035 -0.07 -0.2951 -0.8388 2068588 IFLab1_005766 CCCN1C(=O)/C(=C/2\SC(=S)N(CC=C)C2=O)/c3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G03 compound treatment 0.324 -7.5E-4 -0.03 0.326 0.0035 0.07 0.0309 0.3918 1357017 IFLab1_005767 O=S(=O)(N1CCCC1)c2ccc(cc2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G04 compound treatment 0.311 -0.0138 -0.54 0.309 -0.0135 -0.28 -0.582 -0.9542 2068589 IFLab1_005768 CC(Oc1ccc(F)cc1)C(=O)Oc2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G05 compound treatment 0.313 -0.0118 -0.46 0.317 -0.0055 -0.12 -0.4081 -0.8571 1551594 IFLab1_005769 Oc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G06 compound treatment 0.315 -0.00975 -0.38 0.314 -0.0085 -0.18 -0.3968 -0.939 2068590 IFLab1_005770 CC(C)Oc1ccc(cc1)C(=O)NCc2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G07 compound treatment 0.321 -0.00375 -0.15 0.336 0.0135 0.28 0.0955 0.2997 2068591 IFLab1_005771 Clc1ccc(Cn2ncc3c(ncnc23)N4CCCCC4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G08 compound treatment 0.324 -7.5E-4 -0.03 0.33 0.0075 0.16 0.0901 0.5644 2068592 IFLab1_005772 Cc1cc(C)n(n1)C(=O)CNC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G09 compound treatment 0.339 0.0143 0.56 0.325 0.0025 0.05 0.4332 0.7698 2068593 IFLab1_005773 CC1CCN(CC1)c2ncnc3n(Cc4ccc(C)cc4)ncc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G10 compound treatment 0.334 0.00925 0.36 0.327 0.0045 0.09 0.3238 0.8618 1741156 IFLab1_005774 Cc1ccc(cc1)c2nnnn2CS(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G11 compound treatment 0.333 0.00825 0.32 0.329 0.0065 0.14 0.3255 0.9255 1719877 IFLab1_005775 COc1ccccc1N(CC(O)CN2C(C)CCCC2C)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G12 compound treatment 0.333 0.00825 0.32 0.331 0.0085 0.18 0.3551 0.96 2068594 IFLab1_005776 CC1CC(C)CN(CC(O)COc2cccc(C)c2)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G13 compound treatment 0.331 0.00625 0.25 0.325 0.0025 0.05 0.2108 0.8388 2068595 IFLab1_005777 CN(C)C(=O)CSc1nc(N)cc(O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G14 compound treatment 0.32 -0.00475 -0.19 0.322 -5.0E-4 -0.01 -0.1395 -0.7456 2068596 IFLab1_005778 CCN1CCN(CC(O)COc2cccc(C)c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G15 compound treatment 0.317 -0.00775 -0.3 0.331 0.0085 0.18 -0.0897 -0.2542 2068597 IFLab1_005779 OC(=O)c1ccccc1SC2CC(=O)N(C3CCCCC3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G16 compound treatment 0.318 -0.00675 -0.27 0.327 0.0045 0.09 -0.1211 -0.4299 2068598 IFLab1_005780 CCOC(=O)N1CCN(CC1)C(=O)c2sc3cc(F)ccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G17 compound treatment 0.324 -7.5E-4 -0.03 0.33 0.0075 0.16 0.0901 0.5644 1874324 IFLab1_005781 COC(=O)c1c2C(=O)c3ccccc3C(=O)c2n4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G18 compound treatment 0.338 0.0133 0.52 0.327 0.0045 0.09 0.435 0.8216 2068599 IFLab1_005782 C(Nc1ncnc2sccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G19 compound treatment 0.338 0.0133 0.52 0.331 0.0085 0.18 0.4942 0.8977 2068600 IFLab1_005783 CCN(CC)S(=O)(=O)c1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G20 compound treatment 0.333 0.00825 0.32 0.334 0.0115 0.24 0.3995 0.9892 2068601 IFLab1_005784 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G21 compound treatment 0.321 -0.00375 -0.15 0.34 0.0175 0.37 0.1547 0.3918 1874958 IFLab1_005785 COc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G22 compound treatment 0.314 -0.0107 -0.42 0.319 -0.0035 -0.07 -0.3507 -0.8175 2068602 IFLab1_005786 FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)N2CCN(CC2)C(=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G23 mock treatment 0.317 -0.00775 -0.3 0.316 -0.0065 -0.14 -0.3116 -0.9339 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 G24 positive control 0.081 -0.244 -9.58 0.08 -0.242 -5.07 -10.365 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H01 compound treatment 0.332 0.00725 0.29 0.33 0.0075 0.16 0.3125 0.9605 2068603 IFLab1_005787 Cc1cc2ccccc2n3c(SCC(=O)NCC4CCCO4)nnc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H02 compound treatment 0.319 -0.00575 -0.23 0.319 -0.0035 -0.07 -0.2117 -0.8906 1436799 IFLab1_005788 Clc1ccc(cc1Cl)C(=O)COC(=O)c2ccc3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H03 compound treatment 0.316 -0.00875 -0.34 0.319 -0.0035 -0.07 -0.2951 -0.8388 1430777 IFLab1_005789 COC(=O)CCC(=O)Nc1sc(C)c(C)c1C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H04 compound treatment 0.317 -0.00775 -0.3 0.326 0.0035 0.07 -0.1637 -0.5223 2068604 IFLab1_005790 Nc1nc(cs1)c2cccc(NS(=O)(=O)c3ccccc3)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H05 compound treatment 0.322 -0.00275 -0.11 0.323 5.0E-4 0.01 -0.0691 -0.6357 2068605 IFLab1_005791 COC(=O)c1c(NC(=O)C2CC2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H06 compound treatment 0.319 -0.00575 -0.23 0.318 -0.0045 -0.09 -0.2264 -0.9246 2068606 IFLab1_005792 NC(=O)C1CCN(CC1)C(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H07 compound treatment 0.334 0.00925 0.36 0.351 0.0285 0.6 0.6789 0.9719 1588356 IFLab1_005793 Cc1sc(NC(=O)C2CC2)c(C(=O)N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H08 compound treatment 0.439 0.114 4.49 0.413 0.0905 1.89 4.5155 0.9263 2068607 IFLab1_005794 COc1cccc(c1)C2CC(=O)Nc3sc4c(C)c(C#N)c(N)nc4c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H09 compound treatment 0.322 -0.00275 -0.11 0.336 0.0135 0.28 0.1233 0.4076 1703452 IFLab1_005795 Cc1cc(C)n(n1)C(=O)c2ccc(NC(=O)C3CC3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H10 compound treatment 0.344 0.0193 0.76 0.333 0.0105 0.22 0.6906 0.8762 2068608 IFLab1_005796 CS(=O)(=O)N1CCSC1c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H11 compound treatment 0.334 0.00925 0.36 0.331 0.0085 0.18 0.3829 0.9459 2068609 IFLab1_005797 CN(Cc1ccccc1)C(=O)/C=C/c2ccc(C)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H12 compound treatment 0.373 0.0483 1.9 0.374 0.0515 1.08 2.1035 0.9641 2068610 IFLab1_005798 COc1ccc2cc(sc(=O)c2c1OC)C(=O)OC(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H13 compound treatment 0.328 0.00325 0.13 0.335 0.0125 0.26 0.2753 0.9457 1243065 IFLab1_005799 OC(=O)C1CCCCC1C(=O)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H14 compound treatment 0.338 0.0133 0.52 0.338 0.0155 0.32 0.5977 0.974 1145455 IFLab1_005800 CC(=O)Nc1cccc(NC(=O)c2cccnc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H15 compound treatment 0.318 -0.00675 -0.27 0.336 0.0135 0.28 0.0121 0.0312 2068611 IFLab1_005801 CC(=O)Oc1cn(C)c2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H16 compound treatment 0.322 -0.00275 -0.11 0.338 0.0155 0.32 0.1529 0.4472 2068612 IFLab1_005802 COC(=O)Oc1ccc2c3CCCCc3c(=O)oc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H17 compound treatment 0.397 0.0722 2.84 0.386 0.0635 1.33 2.9483 0.9401 1482525 IFLab1_005803 Nc1c(sc2nc3CCCc3cc12)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H18 compound treatment 0.424 0.0993 3.9 0.417 0.0945 1.98 4.1577 0.9504 2068613 IFLab1_005804 Cc1cccc2nc(CSC(=S)NCC3CCCO3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H19 compound treatment 0.331 0.00625 0.25 0.333 0.0105 0.22 0.3291 0.9984 2068614 IFLab1_005805 O=C(N1CCc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H20 compound treatment 0.334 0.00925 0.36 0.334 0.0115 0.24 0.4273 0.9799 2068615 IFLab1_005806 COc1cc(C)c(C)cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H21 compound treatment 0.332 0.00725 0.29 0.331 0.0085 0.18 0.3273 0.9742 2068616 IFLab1_005807 CCCS(=O)(=O)N1CCN(CC1)c2ccccc2F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H22 compound treatment 0.334 0.00925 0.36 0.328 0.0055 0.12 0.3386 0.8875 2068617 IFLab1_005808 CCOc1ccc(Cl)cc1S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H23 mock treatment 0.326 0.00125 0.05 0.322 -5.0E-4 -0.01 0.0274 0.5444 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 H24 positive control 0.084 -0.241 -9.47 0.082 -0.24 -5.03 -10.252 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I01 compound treatment 0.338 0.0133 0.52 0.337 0.0145 0.3 0.5829 0.9669 1711638 IFLab1_005809 CC(=O)Nc1ccc(NC(=O)c2ccccc2OC(=O)C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I02 compound treatment 0.329 0.00425 0.17 0.341 0.0185 0.39 0.3919 0.9294 2068618 IFLab1_005810 COCCN1C(=O)/C(=C/c2cn(nc2c3ccccc3)c4ccccc4)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I03 compound treatment 0.327 0.00225 0.09 0.338 0.0155 0.32 0.2919 0.8682 2068619 IFLab1_005811 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccn4)C(=O)CC(C)(C)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I04 compound treatment 0.318 -0.00675 -0.27 0.329 0.0065 0.14 -0.0915 -0.3068 1875413 IFLab1_005812 CC(Oc1ccc(F)cc1)C(=O)Oc2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I05 compound treatment 0.328 0.00325 0.13 0.337 0.0145 0.3 0.3049 0.9261 1664813 IFLab1_005813 Clc1ccccc1C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I06 compound treatment 0.356 0.0313 1.23 0.359 0.0365 0.76 1.4089 0.9738 2068620 IFLab1_005814 COC(=O)Nc1sc(nc1c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I07 compound treatment 0.335 0.0103 0.4 0.346 0.0235 0.49 0.6327 0.9951 2068621 IFLab1_005815 CN1CCN(CC1)c2ncnc3n(Cc4ccc(Cl)cc4)ncc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I08 compound treatment 0.349 0.0243 0.95 0.353 0.0305 0.64 1.1255 0.981 1351145 IFLab1_005816 COc1ccc(cc1OC)c2nnc(o2)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I09 compound treatment 0.338 0.0133 0.52 0.339 0.0165 0.35 0.6125 0.98 1693765 IFLab1_005817 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCC(CC2)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I10 compound treatment 0.34 0.0153 0.6 0.343 0.0205 0.43 0.7273 0.9865 1339994 IFLab1_005818 Cc1ccc(cc1)S(=O)(=O)CNC(=O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I11 compound treatment 0.346 0.0213 0.84 0.352 0.0295 0.62 1.0273 0.9889 2068622 IFLab1_005819 CCOC(=O)/C(=C\1/Sc2ccccc2N1C)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I12 compound treatment 0.334 0.00925 0.36 0.33 0.0075 0.16 0.3681 0.9294 2068623 IFLab1_005820 CC1CCCC(C)N1CC(O)COc2cccc(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I13 compound treatment 0.336 0.0113 0.44 0.335 0.0125 0.26 0.4977 0.9686 2068624 IFLab1_005821 CCN(CC)C(=O)CSc1nc(N)cc(O)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I14 compound treatment 0.337 0.0123 0.48 0.34 0.0175 0.37 0.5995 0.9909 1559508 IFLab1_005822 Cc1cccc(OCC(O)Cn2cnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I15 compound treatment 0.337 0.0123 0.48 0.336 0.0135 0.28 0.5403 0.9677 2068625 IFLab1_005823 CCc1ccccc1NC(=O)CC2SC(=N)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I16 compound treatment 0.341 0.0163 0.64 0.338 0.0155 0.32 0.6811 0.9506 1566329 IFLab1_005824 O=C(COC(=O)C1CCN(CC1)S(=O)(=O)c2cccs2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I17 compound treatment 0.344 0.0193 0.76 0.334 0.0115 0.24 0.7054 0.8881 2068626 IFLab1_005825 Nc1cc(O)nc(SCc2ccc(cc2)C(=O)c3ccccc3)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I18 compound treatment 0.353 0.0283 1.11 0.34 0.0175 0.37 1.0444 0.893 2068627 IFLab1_005826 Cc1sc2nc[nH]c(=O)c2c1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I19 compound treatment 0.332 0.00725 0.29 0.343 0.0205 0.43 0.5049 0.9803 2068628 IFLab1_005827 CCCC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I20 compound treatment 0.342 0.0173 0.68 0.34 0.0175 0.37 0.7385 0.9582 2068629 IFLab1_005828 COc1cccc(c1)S(=O)(=O)N2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I21 compound treatment 0.333 0.00825 0.32 0.333 0.0105 0.22 0.3847 0.982 2068630 IFLab1_005829 CCCN1C(=O)/C(=C\2/C(=O)N(Cc3ccc(C)cc3)c4ccccc24)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I22 compound treatment 0.334 0.00925 0.36 0.333 0.0105 0.22 0.4125 0.9709 1526180 IFLab1_005830 Fc1cccc(F)c1S(=O)(=O)N2CCN(CC2)C(=O)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I23 mock treatment 0.328 0.00325 0.13 0.325 0.0025 0.05 0.1273 0.9223 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 I24 positive control 0.085 -0.24 -9.43 0.082 -0.24 -5.03 -10.2242 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J01 compound treatment 0.332 0.00725 0.29 0.333 0.0105 0.22 0.3569 0.9917 2068631 IFLab1_005831 Cc1cc(O)n(n1)C(=S)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J02 compound treatment 0.319 -0.00575 -0.23 0.322 -5.0E-4 -0.01 -0.1673 -0.739 2068632 IFLab1_005832 Brc1ccc(nc1)C(=O)OCC(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J03 compound treatment 0.32 -0.00475 -0.19 0.32 -0.0025 -0.05 -0.1691 -0.8716 2068633 IFLab1_005833 Cn1ccnc1C(O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J04 compound treatment 0.325 2.5E-4 0.01 0.331 0.0085 0.18 0.1327 0.745 2068634 IFLab1_005834 O=C(COC(=O)c1cccs1)c2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J05 compound treatment 0.324 -7.5E-4 -0.03 0.321 -0.0015 -0.03 -0.043 -0.9995 1191156 IFLab1_005835 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)C3CC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J06 compound treatment 0.339 0.0143 0.56 0.336 0.0135 0.28 0.5959 0.9497 1131862 IFLab1_005836 Cc1cc(NCc2cccnc2)n3c4ccccc4nc3c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J07 compound treatment 0.363 0.0382 1.5 0.373 0.0505 1.06 1.8107 0.9851 2068635 IFLab1_005837 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)/C=C/c3ccco3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J08 compound treatment 0.33 0.00525 0.21 0.334 0.0115 0.24 0.3161 0.9971 2068636 IFLab1_005838 O=C(CSC1=C(C#N)C(CC(=O)N1)c2ccco2)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J09 compound treatment 0.359 0.0343 1.35 0.35 0.0275 0.58 1.3591 0.9281 2068637 IFLab1_005839 COc1ccc(/C=C/C(=O)Nc2nccs2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J10 compound treatment 0.327 0.00225 0.09 0.339 0.0165 0.35 0.3067 0.8605 2068638 IFLab1_005840 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J11 compound treatment 0.352 0.0273 1.07 0.346 0.0235 0.49 1.1053 0.9376 2068639 IFLab1_005841 Cc1ccc(/C=C/C(=O)NCC2CCCO2)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J12 compound treatment 0.34 0.0153 0.6 0.332 0.0095 0.2 0.5646 0.8937 2068640 IFLab1_005842 CCOC(=O)c1cc2ccccc2c(=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J13 compound treatment 0.323 -0.00175 -0.07 0.323 5.0E-4 0.01 -0.0413 -0.5928 1707491 IFLab1_005843 COc1cc(cc(OC)c1OC)C(=O)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J14 compound treatment 0.338 0.0133 0.52 0.342 0.0195 0.41 0.6569 0.9927 2068641 IFLab1_005844 Cc1ccc(cc1NC(=O)c2cccnc2)S(=O)(=O)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J15 compound treatment 0.362 0.0372 1.46 0.362 0.0395 0.83 1.6201 0.9633 2068642 IFLab1_005845 O=C(Nc1nccs1)/C=C/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J16 compound treatment 0.345 0.0203 0.8 0.338 0.0155 0.32 0.7923 0.9216 2068643 IFLab1_005846 CN(C1CCS(=O)(=O)C1)C(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J17 compound treatment 0.339 0.0143 0.56 0.333 0.0105 0.22 0.5515 0.9165 1007321 IFLab1_005847 CCOC(=O)c1[nH]c(C)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J18 compound treatment 0.385 0.0602 2.37 0.389 0.0665 1.39 2.6591 0.9678 2068644 IFLab1_005848 Cc1cccc2nc(CSC(=S)NCc3cccnc3)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J19 compound treatment 0.34 0.0153 0.6 0.348 0.0255 0.53 0.8013 0.9983 1374001 IFLab1_005849 O=C(COc1ccccc1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J20 compound treatment 0.331 0.00625 0.25 0.331 0.0085 0.18 0.2995 0.9874 2068645 IFLab1_005850 COc1cc(C)c(cc1S(=O)(=O)N2CCCC2)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J21 compound treatment 0.343 0.0182 0.72 0.341 0.0185 0.39 0.7811 0.9581 1361126 IFLab1_005851 Cc1ccc(cc1C(=O)O)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J22 compound treatment 0.333 0.00825 0.32 0.339 0.0165 0.35 0.4735 0.9995 2068646 IFLab1_005852 CCOc1ccc(Cl)cc1S(=O)(=O)N2CC(C)OC(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J23 mock treatment 0.323 -0.00175 -0.07 0.322 -5.0E-4 -0.01 -0.0561 -0.8054 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 J24 positive control 0.084 -0.241 -9.47 0.084 -0.238 -4.99 -10.2224 -0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K01 compound treatment 0.345 0.0203 0.8 0.347 0.0245 0.51 0.9255 0.9773 2068647 IFLab1_005853 Clc1cccc(c1)N2CCN(CC2)C(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K02 compound treatment 0.312 -0.0127 -0.5 0.315 -0.0075 -0.16 -0.4655 -0.8861 2068648 IFLab1_005854 OC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K03 compound treatment 0.318 -0.00675 -0.27 0.317 -0.0055 -0.12 -0.269 -0.9301 2068649 IFLab1_005855 O=C1CCCC2=C1C(C3=C(CCCC3=O)O2)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K04 compound treatment 0.348 0.0233 0.91 0.353 0.0305 0.64 1.0977 0.9846 2068650 IFLab1_005856 CN1C(=O)/C(=C/C2=Cc3ccccc3OC2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K05 compound treatment 0.314 -0.0107 -0.42 0.315 -0.0075 -0.16 -0.4098 -0.909 2068651 IFLab1_005857 Cc1cc(NCc2ccccn2)n3c4ccccc4nc3c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K06 compound treatment 0.342 0.0173 0.68 0.34 0.0175 0.37 0.7385 0.9582 2068652 IFLab1_005858 Cc1ccc(SCC(=O)Nc2nnc(SCc3ccccc3)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K07 compound treatment 0.324 -7.5E-4 -0.03 0.339 0.0165 0.35 0.2233 0.6444 2068653 IFLab1_005859 CCN(CC)c1ncnc2n(Cc3ccc(Cl)cc3)ncc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K08 compound treatment 0.348 0.0233 0.91 0.336 0.0135 0.28 0.8462 0.8844 2068654 IFLab1_005860 O=S1(=O)CCC(C1)n2nnnc2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K09 compound treatment 0.343 0.0182 0.72 0.331 0.0085 0.18 0.6332 0.8565 1603138 IFLab1_005861 COc1ccc(cc1OC)S(=O)(=O)N2CCc3ccccc3C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K10 compound treatment 0.337 0.0123 0.48 0.329 0.0065 0.14 0.4368 0.8727 2068655 IFLab1_005862 COC(=O)NC(=C(Cl)Cl)S(=O)(=O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K11 compound treatment 0.352 0.0273 1.07 0.335 0.0125 0.26 0.9426 0.8546 2068656 IFLab1_005863 CC(C)CCNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K12 compound treatment 0.337 0.0123 0.48 0.325 0.0025 0.05 0.3776 0.7793 2068657 IFLab1_005864 CC1CN(CC(O)COc2cccc(C)c2)CC(C)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K13 compound treatment 0.35 0.0253 0.99 0.344 0.0215 0.45 1.0201 0.9359 2068658 IFLab1_005865 Nc1cc(O)nc(SCC(=O)Nc2ccccc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K14 compound treatment 0.337 0.0123 0.48 0.333 0.0105 0.22 0.4959 0.9368 2068659 IFLab1_005866 Cc1cccc(OCC(O)CN2C(C)(C)CCCC2(C)C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K15 compound treatment 0.326 0.00125 0.05 0.336 0.0135 0.28 0.2345 0.8178 2068660 IFLab1_005867 FC(F)(F)Sc1ccccc1NC(=O)CC2SC(=N)NC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K16 compound treatment 0.362 0.0372 1.46 0.338 0.0155 0.32 1.265 0.8433 2068661 IFLab1_005868 Fc1ccc2c(Cl)c(sc2c1)C(=O)Nc3ccon3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K17 compound treatment 0.354 0.0293 1.15 0.351 0.0285 0.6 1.2349 0.9532 2068662 IFLab1_005869 O=C(CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccco3)NC4CC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K18 compound treatment 0.323 -0.00175 -0.07 0.324 0.0015 0.03 -0.0265 -0.3498 2068663 IFLab1_005870 COCCn1c(C)cc(C(=O)CSc2ncnc3sc(C)c(C)c23)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K19 compound treatment 0.336 0.0113 0.44 0.341 0.0185 0.39 0.5865 0.9978 2068664 IFLab1_005871 Nc1nc2ccc(cc2s1)S(=O)(=O)N3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K20 compound treatment 0.399 0.0742 2.92 0.393 0.0705 1.48 3.1075 0.95 2068665 IFLab1_005872 COc1ccc(cc1)c2ccc(cc2)S(=O)(=O)N3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K21 compound treatment 0.341 0.0163 0.64 0.337 0.0145 0.3 0.6663 0.9421 2068666 IFLab1_005873 COCCN1C(=O)/C(=C\2/C(=O)N(Cc3ccc(C)cc3)c4ccccc24)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K22 compound treatment 0.338 0.0133 0.52 0.334 0.0115 0.24 0.5385 0.9385 2068667 IFLab1_005874 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)Nc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K23 mock treatment 0.322 -0.00275 -0.11 0.32 -0.0025 -0.05 -0.1134 -0.9445 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 K24 positive control 0.086 -0.239 -9.39 0.085 -0.237 -4.97 -10.152 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L01 compound treatment 0.326 0.00125 0.05 0.327 0.0045 0.09 0.1013 0.954 1637501 IFLab1_005875 O=C(NC1CCCCC1NC(=O)c2cccs2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L02 compound treatment 0.316 -0.00875 -0.34 0.332 0.0095 0.2 -0.1027 -0.2585 2068668 IFLab1_005876 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3ccc(Cl)c(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L03 compound treatment 0.322 -0.00275 -0.11 0.343 0.0205 0.43 0.2269 0.5128 1040671 IFLab1_005877 CC(=O)OCC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L04 compound treatment 0.314 -0.0107 -0.42 0.319 -0.0035 -0.07 -0.3507 -0.8175 2068669 IFLab1_005878 CC(OC(=O)c1cccs1)C(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L05 compound treatment 0.324 -7.5E-4 -0.03 0.338 0.0155 0.32 0.2085 0.6402 2068670 IFLab1_005879 Cc1cc(C)nc(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L06 compound treatment 0.325 2.5E-4 0.01 0.328 0.0055 0.12 0.0883 0.7647 2068671 IFLab1_005880 Cc1cc(NCCCN2CCOCC2)n3c4ccccc4nc3c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L07 compound treatment 0.351 0.0262 1.03 0.361 0.0385 0.81 1.2995 0.9925 2068672 IFLab1_005881 O=C(Nc1ccc(Nc2ccccc2)cc1)/C=C/c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L08 compound treatment 0.33 0.00525 0.21 0.343 0.0205 0.43 0.4493 0.9438 2068673 IFLab1_005882 O=C(CSC1=C(C#N)C(CC(=O)N1)c2ccco2)NCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L09 compound treatment 0.367 0.0423 1.66 0.356 0.0335 0.7 1.6703 0.9264 2068674 IFLab1_005883 COc1ccc(/C=C/C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L10 compound treatment 0.336 0.0113 0.44 0.335 0.0125 0.26 0.4977 0.9686 2068675 IFLab1_005884 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCSC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L11 compound treatment 0.367 0.0423 1.66 0.384 0.0615 1.29 2.0847 0.992 2068676 IFLab1_005885 CN(Cc1ccccc1)S(=O)(=O)c2ccc(NC(=O)/C=C/c3ccco3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L12 compound treatment 0.336 0.0113 0.44 0.331 0.0085 0.18 0.4385 0.9199 2068677 IFLab1_005886 COC(=O)c1cc2ccccc2c(=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L13 compound treatment 0.341 0.0163 0.64 0.344 0.0215 0.45 0.7699 0.9853 1197766 IFLab1_005887 Cc1ccc(CNCC2CCCO2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L14 compound treatment 0.336 0.0113 0.44 0.339 0.0165 0.35 0.5569 0.9925 1602731 IFLab1_005888 CS(=O)(=O)c1ccc(Cl)c(NC(=O)c2cccnc2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L15 compound treatment 0.339 0.0143 0.56 0.339 0.0165 0.35 0.6403 0.973 1364252 IFLab1_005889 CCOC(=O)c1c(NC(=O)CCC(=O)OC)sc2CCCc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L16 compound treatment 0.35 0.0253 0.99 0.342 0.0195 0.41 0.9905 0.9228 2068678 IFLab1_005890 COc1cccc(c1)c2nc3ccccc3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L17 compound treatment 0.336 0.0113 0.44 0.335 0.0125 0.26 0.4977 0.9686 1319156 IFLab1_005891 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L18 compound treatment 0.358 0.0333 1.31 0.351 0.0285 0.6 1.3461 0.9368 2068679 IFLab1_005892 S=C(NCc1ccco1)SCc2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L19 compound treatment 0.34 0.0153 0.6 0.334 0.0115 0.24 0.5941 0.9196 1413491 IFLab1_005893 COc1ccc(cc1OC)C(O)c2nccn2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L20 compound treatment 0.341 0.0163 0.64 0.336 0.0135 0.28 0.6515 0.9327 2068680 IFLab1_005894 O=S(=O)(N1CCCC1)c2ccc(cc2)C3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L21 compound treatment 0.34 0.0153 0.6 0.337 0.0145 0.3 0.6385 0.9502 2068681 IFLab1_005895 Fc1ccccc1N2CCN(CC2)S(=O)(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L22 compound treatment 0.321 -0.00375 -0.15 0.319 -0.0035 -0.07 -0.156 -0.9479 2068682 IFLab1_005896 COc1ccc(cc1C)S(=O)(=O)NC2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L23 mock treatment 0.327 0.00225 0.09 0.322 -5.0E-4 -0.01 0.0552 0.6192 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 L24 positive control 0.086 -0.239 -9.39 0.085 -0.237 -4.97 -10.152 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M01 compound treatment 0.33 0.00525 0.21 0.338 0.0155 0.32 0.3753 0.9762 2068683 IFLab1_005897 CCn1c(SCC(=O)O)nnc1c2sc3cc(Cl)ccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M02 compound treatment 0.359 0.0343 1.35 0.387 0.0645 1.35 1.9066 1.0 1875263 IFLab1_005898 Nc1sc2CCCc2c1C(=O)NCCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M03 compound treatment 0.288 -0.0367 -1.44 0.294 -0.0285 -0.6 -1.4434 -0.9234 2068684 IFLab1_005899 CCCCC1C2=C(CCCC2=O)OC3=C1C(=O)CCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M04 compound treatment 0.327 0.00225 0.09 0.341 0.0185 0.39 0.3363 0.8469 2068685 IFLab1_005900 Nc1nc(cs1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M05 compound treatment 0.393 0.0683 2.68 0.396 0.0735 1.54 2.9851 0.9651 2068686 IFLab1_005901 Clc1ccc(cc1)c2csc3nc[nH]c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M06 compound treatment 0.335 0.0103 0.4 0.347 0.0245 0.51 0.6475 0.9929 2068687 IFLab1_005902 N#C/C(=C/C1=Cc2ccccc2OC1)/c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M07 compound treatment 0.321 -0.00375 -0.15 0.328 0.0055 0.12 -0.0229 -0.1223 2068688 IFLab1_005903 Clc1ccc(Cn2ncc3c(NC4CCCCC4)ncnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M08 compound treatment 0.351 0.0262 1.03 0.365 0.0425 0.89 1.3587 0.9973 2068689 IFLab1_005904 CC1Oc2ccccc2C=C1/C=C(\NC(=O)c3ccccc3)/C(=O)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M09 compound treatment 0.333 0.00825 0.32 0.325 0.0025 0.05 0.2664 0.8107 2068690 IFLab1_005905 CCOc1ccc(OCC)c(c1)S(=O)(=O)N(C)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M10 compound treatment 0.339 0.0143 0.56 0.337 0.0145 0.3 0.6107 0.9585 2068691 IFLab1_005906 ClC(=CNC(=O)c1ccccc1)Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M11 compound treatment 0.316 -0.00875 -0.34 0.32 -0.0025 -0.05 -0.2803 -0.8054 2068692 IFLab1_005907 CNCC(O)Cn1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M12 compound treatment 0.335 0.0103 0.4 0.348 0.0255 0.53 0.6623 0.9904 2068693 IFLab1_005908 CCOC(=O)C1CCN(CC(O)COc2cccc(C)c2)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M13 compound treatment 0.322 -0.00275 -0.11 0.339 0.0165 0.35 0.1677 0.4635 2068694 IFLab1_005909 CN(C)C(=O)CSc1nc(O)c2c(C)cc(C)nc2n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M14 compound treatment 0.343 0.0182 0.72 0.341 0.0185 0.39 0.7811 0.9581 2068695 IFLab1_005910 CC1CCN(CC(O)COc2ccccc2Br)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M15 compound treatment 0.336 0.0113 0.44 0.338 0.0155 0.32 0.5421 0.9884 2068696 IFLab1_005911 Cc1oc2nc(SCC(=O)N3CCCCC3)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M16 compound treatment 0.336 0.0113 0.44 0.331 0.0085 0.18 0.4385 0.9199 2068697 IFLab1_005912 CCn1c(SC)nnc1c2nnc(SC)n2CC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M17 compound treatment 0.523 0.198 7.79 0.538 0.216 4.51 8.7005 0.9662 2068698 IFLab1_005913 CSCCC(N1C(=O)/C(=C/c2c[nH]c3ccccc23)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M18 compound treatment 0.344 0.0193 0.76 0.344 0.0215 0.45 0.8533 0.9691 2068699 IFLab1_005914 COc1cccc(NC(=O)CSc2nnc3ccccn23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M19 compound treatment 0.342 0.0173 0.68 0.333 0.0105 0.22 0.635 0.8906 2068700 IFLab1_005915 O=C(Nc1nc2ccc(cc2s1)S(=O)(=O)N3CCCC3)/C=C/c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M20 compound treatment 0.304 -0.0208 -0.82 0.3 -0.0225 -0.47 -0.9098 -0.9659 1149422 IFLab1_005916 Cc1ccccc1Oc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M21 compound treatment 0.342 0.0173 0.68 0.344 0.0215 0.45 0.7977 0.9801 2068701 IFLab1_005917 CCCN1C(=O)/C(=C/2\SC(=S)N(C)C2=O)/c3cc(Br)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M22 compound treatment 0.336 0.0113 0.44 0.342 0.0195 0.41 0.6013 0.9992 2068702 IFLab1_005918 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)NCc3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M23 mock treatment 0.326 0.00125 0.05 0.328 0.0055 0.12 0.1161 0.928 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 M24 positive control 0.087 -0.238 -9.35 0.087 -0.235 -4.93 -10.0946 -0.9553 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N01 compound treatment 0.321 -0.00375 -0.15 0.326 0.0035 0.07 -0.0525 -0.3187 1464164 IFLab1_005919 Brc1ccc(o1)C(=O)NCC2CCCO2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N02 compound treatment 0.315 -0.00975 -0.38 0.315 -0.0075 -0.16 -0.382 -0.9223 2068703 IFLab1_005920 C/C(=C/C(=O)O)/C(=O)Nc1sc2CCCCc2c1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N03 compound treatment 0.31 -0.0147 -0.58 0.317 -0.0055 -0.12 -0.4915 -0.8312 2068704 IFLab1_005921 Cc1cc(C)nc(SCCS(=O)(=O)c2nc3ccccc3s2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N04 compound treatment 0.317 -0.00775 -0.3 0.323 5.0E-4 0.01 -0.2081 -0.6824 2068705 IFLab1_005922 OCCN1CCN(CC1)C(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N05 compound treatment 0.315 -0.00975 -0.38 0.313 -0.0095 -0.2 -0.4116 -0.9532 1721418 IFLab1_005923 O=C(NCC1CCCO1)C2CCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N06 compound treatment 0.137 -0.188 -7.38 0.122 -0.201 -4.2 -8.1866 -0.9642 1047107 IFLab1_005924 CC(=O)Nc1ccc(cc1)N2C(=O)C=CC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N07 compound treatment 0.334 0.00925 0.36 0.323 5.0E-4 0.01 0.2646 0.7271 1189856 IFLab1_005925 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)c3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N08 compound treatment 0.372 0.0473 1.86 0.372 0.0495 1.04 2.0461 0.9619 1873360 IFLab1_005926 COc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N09 compound treatment 0.354 0.0293 1.15 0.343 0.0205 0.43 1.1165 0.9096 1181825 IFLab1_005927 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C4CC4)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N10 compound treatment 0.351 0.0262 1.03 0.341 0.0185 0.39 1.0035 0.9104 2068706 IFLab1_005928 CC(C)CC(=O)Nc1nc(cs1)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N11 compound treatment 0.344 0.0193 0.76 0.357 0.0345 0.72 1.0457 0.9997 2068707 IFLab1_005929 Fc1ccc(/C=C/C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N12 compound treatment 0.342 0.0173 0.68 0.326 0.0035 0.07 0.5314 0.7789 2068708 IFLab1_005930 CC(C)OC(=O)c1cc2ccccc2c(=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N13 compound treatment 0.344 0.0193 0.76 0.343 0.0205 0.43 0.8385 0.9638 2068709 IFLab1_005931 O=C(COc1ccccc1)N2CCNC(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N14 compound treatment 0.343 0.0182 0.72 0.343 0.0205 0.43 0.8107 0.9698 2068710 IFLab1_005932 CC(=O)Nc1cccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N15 compound treatment 0.348 0.0233 0.91 0.336 0.0135 0.28 0.8462 0.8844 1263468 IFLab1_005933 O=C(NC1CCSC1=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N16 compound treatment 0.342 0.0173 0.68 0.339 0.0165 0.35 0.7237 0.9509 1189678 IFLab1_005934 COc1ccc(cc1OC)c2nc3ccccc3c(=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N17 compound treatment 0.337 0.0123 0.48 0.334 0.0115 0.24 0.5107 0.9486 2068711 IFLab1_005935 O=C(/C=C/c1ccccc1)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N18 compound treatment 0.308 -0.0168 -0.66 0.308 -0.0145 -0.3 -0.6802 -0.9381 2068712 IFLab1_005936 CN1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N19 compound treatment 0.34 0.0153 0.6 0.342 0.0195 0.41 0.7125 0.9824 1528199 IFLab1_005937 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N20 compound treatment 0.336 0.0113 0.44 0.368 0.0455 0.95 0.986 0.9392 2068713 IFLab1_005938 COc1cc(C)c(cc1S(=O)(=O)NCCCn2ccnc2)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N21 compound treatment 0.374 0.0493 1.94 0.379 0.0565 1.18 2.2053 0.972 2068714 IFLab1_005939 O=C(Nc1ccc(cc1)c2cn3ccsc3n2)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N22 compound treatment 0.356 0.0313 1.23 0.345 0.0225 0.47 1.2017 0.9133 2068715 IFLab1_005940 COc1ccc(c2ccccc12)S(=O)(=O)NC3CCCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N23 mock treatment 0.305 -0.0198 -0.78 0.314 -0.0085 -0.18 -0.6749 -0.8471 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 N24 positive control 0.088 -0.237 -9.31 0.089 -0.234 -4.89 -10.0372 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O01 compound treatment 0.323 -0.00175 -0.07 0.326 0.0035 0.07 0.0031 0.0312 2068716 IFLab1_005941 CCn1c(SCC(=O)N)nnc1c2sc3cc(Cl)ccc3c2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O02 compound treatment 0.329 0.00425 0.17 0.341 0.0185 0.39 0.3919 0.9294 1875264 IFLab1_005942 Nc1c(oc2ccccc12)C(=O)Nc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O03 compound treatment 0.303 -0.0217 -0.86 0.305 -0.0175 -0.37 -0.8636 -0.9284 2068717 IFLab1_005943 O=C1CCCC2=C1C(C3=C(CCCC3=O)O2)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O04 compound treatment 0.322 -0.00275 -0.11 0.316 -0.0065 -0.14 -0.1726 -0.9935 2068718 IFLab1_005944 Clc1ccccc1NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CC=C)C3=O)/c4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O05 compound treatment 0.336 0.0113 0.44 0.333 0.0105 0.22 0.4681 0.9479 1867276 IFLab1_005945 CCC(C)(C)C1CCc2sc3nc[nH]c(=O)c3c2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O06 compound treatment 0.32 -0.00475 -0.19 0.318 -0.0045 -0.09 -0.1986 -0.9497 2068719 IFLab1_005946 OC1=C(C(N(Cc2ccco2)C1=O)c3ccccc3)C(=O)c4ccc(OCC=C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O07 compound treatment 0.333 0.00825 0.32 0.343 0.0205 0.43 0.5327 0.9905 2068720 IFLab1_005947 Clc1ccc(Cn2ncc3c(NCc4cccnc4)ncnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O08 compound treatment 0.341 0.0163 0.64 0.342 0.0195 0.41 0.7403 0.9765 2068721 IFLab1_005948 Cc1oc2nc(SCC(=O)NC3CCCCC3)nc(N)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O09 compound treatment 0.318 -0.00675 -0.27 0.321 -0.0015 -0.03 -0.2099 -0.7853 2068722 IFLab1_005949 COc1ccc(cc1C)S(=O)(=O)N(C)C2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O10 compound treatment 0.327 0.00225 0.09 0.318 -0.0045 -0.09 -0.004 -0.0312 1629304 IFLab1_005950 Cn1cnnc1SC2CCCCC2NS(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O11 compound treatment 0.357 0.0323 1.27 0.363 0.0405 0.85 1.4959 0.9808 1139707 IFLab1_005951 CS(=O)(=O)N1CCN(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O12 compound treatment 0.338 0.0133 0.52 0.33 0.0075 0.16 0.4794 0.881 2068723 IFLab1_005952 CCOC(=O)C1CCCN(CC(O)COc2cccc(C)c2)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O13 compound treatment 0.34 0.0153 0.6 0.335 0.0125 0.26 0.6089 0.9309 2068724 IFLab1_005953 COC(=O)CSc1nc(nc2CCCCc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O14 compound treatment 0.341 0.0163 0.64 0.338 0.0155 0.32 0.6811 0.9506 2068725 IFLab1_005954 CCOC(=O)C1CCCN(CC(O)COc2ccccc2Br)C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O15 compound treatment 0.336 0.0113 0.44 0.335 0.0125 0.26 0.4977 0.9686 1510267 IFLab1_005955 COC(=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O16 compound treatment 0.344 0.0193 0.76 0.346 0.0235 0.49 0.8829 0.9782 2068726 IFLab1_005956 C(CNc1ncnc2scc(c3ccccc3)c12)CN4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O17 compound treatment 0.406 0.0813 3.19 0.412 0.0895 1.87 3.5833 0.9676 2068727 IFLab1_005957 CCOc1ccccc1N2C(=O)/C(=C/c3c[nH]c4ccccc34)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O18 compound treatment 0.335 0.0103 0.4 0.338 0.0155 0.32 0.5143 0.9942 1202252 IFLab1_005958 Cc1cc2nnc(SCC(=O)N3CCCC3)n2c4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O19 compound treatment 0.34 0.0153 0.6 0.339 0.0165 0.35 0.6681 0.9656 2068728 IFLab1_005959 CC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O20 compound treatment 0.327 0.00225 0.09 0.337 0.0145 0.3 0.2771 0.8768 2068729 IFLab1_005960 COc1ccccc1Oc2ccc(cc2)S(=O)(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O21 compound treatment 0.345 0.0203 0.8 0.364 0.0415 0.87 1.1771 0.9991 1875129 IFLab1_005961 O=S(=O)(N1CCCCC1)c2ccc(cc2)c3csc(n3)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O22 compound treatment 0.336 0.0113 0.44 0.344 0.0215 0.45 0.6309 1.0 2068730 IFLab1_005962 Cc1nnc(SCC(=O)Nc2nsc(n2)c3ccccc3)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O23 mock treatment 0.323 -0.00175 -0.07 0.321 -0.0015 -0.03 -0.0708 -0.9368 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 O24 positive control 0.09 -0.235 -9.23 0.091 -0.232 -4.84 -9.9521 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P01 compound treatment 0.336 0.0113 0.44 0.333 0.0105 0.22 0.4681 0.9479 1226990 IFLab1_005963 COC(=O)CCC(=O)Nc1ccc(cc1)c2nc3ccc(C)cc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P02 compound treatment 0.321 -0.00375 -0.15 0.317 -0.0055 -0.12 -0.1856 -0.9925 2068731 IFLab1_005964 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(OC)c(C)cc3C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P03 compound treatment 0.339 0.0143 0.56 0.325 0.0025 0.05 0.4332 0.7698 1088422 IFLab1_005965 O=S(=O)(c1ccccc1)n2ccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P04 compound treatment 0.353 0.0283 1.11 0.346 0.0235 0.49 1.1331 0.9328 2068732 IFLab1_005966 Brc1cc(Br)c2oc(=O)c(cc2c1)C(=O)OCC(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P05 compound treatment 0.349 0.0243 0.95 0.341 0.0185 0.39 0.9479 0.9212 1678677 IFLab1_005967 COc1ccc(cc1)C2C(CC(=O)N2Cc3ccccc3)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P06 compound treatment 0.359 0.0343 1.35 0.349 0.0265 0.55 1.3443 0.9231 2068733 IFLab1_005968 [O-]/[N+](=C\c1c[nH]c2ccccc12)/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P07 compound treatment 0.368 0.0432 1.7 0.363 0.0405 0.85 1.8017 0.9483 2068734 IFLab1_005969 Cc1cc(C)nc(SCCS(=O)c2ccc(cc2)C(C)(C)C)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P08 compound treatment 0.386 0.0612 2.41 0.4 0.0775 1.62 2.8496 0.9815 1873372 IFLab1_005970 O=C(CSC1=C(C#N)C(CC(=O)N1)c2ccco2)N(c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P09 compound treatment 0.358 0.0333 1.31 0.352 0.0295 0.62 1.3609 0.9413 2068735 IFLab1_005971 Cc1ccc(/C=C/C(=O)N2CCN(CC2)C(=O)\C=C\c3ccc(C)o3)o1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P10 compound treatment 0.379 0.0543 2.13 0.375 0.0525 1.1 2.2851 0.9524 2068736 IFLab1_005972 CCCC(=O)Nc1nc(cs1)c2ccc(F)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P11 compound treatment 0.36 0.0352 1.39 0.36 0.0375 0.78 1.5349 0.9637 1860862 IFLab1_005973 COc1ccc(cc1Br)C(=O)n2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P12 compound treatment 0.397 0.0722 2.84 0.399 0.0765 1.6 3.1407 0.9632 2068737 IFLab1_005974 COc1ccc2cc(sc(=O)c2c1OC)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P13 compound treatment 0.382 0.0573 2.25 0.383 0.0605 1.27 2.4869 0.963 1146748 IFLab1_005975 COc1ccc(CC(=O)NCC2CCCO2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P14 compound treatment 0.359 0.0343 1.35 0.359 0.0365 0.76 1.4923 0.9639 2068738 IFLab1_005976 CC(=O)Nc1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P15 compound treatment 0.36 0.0352 1.39 0.37 0.0475 0.99 1.6829 0.9867 2068739 IFLab1_005977 O=C(CCc1ccccc1)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P16 compound treatment 0.354 0.0293 1.15 0.353 0.0305 0.64 1.2645 0.9614 1689389 IFLab1_005978 O=C(Oc1ccc2oc3CCCCc3c2c1)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P17 compound treatment 0.356 0.0313 1.23 0.359 0.0365 0.76 1.4089 0.9738 2068740 IFLab1_005979 Cc1nn(C(=S)N)c(O)c1C(C(C#N)C#N)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P18 compound treatment 0.287 -0.0377 -1.48 0.293 -0.0295 -0.62 -1.486 -0.9244 2068741 IFLab1_005980 CCOC(=O)N1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P19 compound treatment 0.348 0.0233 0.91 0.353 0.0305 0.64 1.0977 0.9846 2068742 IFLab1_005981 NC1=C(C#N)C(c2c(n[nH]c2O1)C(F)(F)F)c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P20 compound treatment 0.354 0.0293 1.15 0.357 0.0345 0.72 1.3237 0.9748 1154230 IFLab1_005982 COc1cc(ccc1F)S(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P21 compound treatment 0.35 0.0253 0.99 0.352 0.0295 0.62 1.1385 0.9739 1569833 IFLab1_005983 O=c1oc2ccccc2cc1c3nnc([nH]3)c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P22 compound treatment 0.338 0.0133 0.52 0.35 0.0275 0.58 0.7753 0.9988 2068743 IFLab1_005984 COc1cc(c(C)cc1C)S(=O)(=O)NC2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P23 mock treatment 0.338 0.0133 0.52 0.334 0.0115 0.24 0.5385 0.9385 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1428 P24 positive control 0.094 -0.231 -9.07 0.094 -0.229 -4.78 -9.7965 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A01 compound treatment 0.337 0.0149 0.58 0.34 0.0162 0.34 0.6531 0.9663 2068744 IFLab1_005985 COc1cc(C)c(C)cc1S(=O)(=O)NC2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A02 compound treatment 0.323 8.75E-4 0.03 0.312 -0.0118 -0.25 -0.1505 -0.6029 1916829 IFLab1_005986 Cn1c(nc2ccccc12)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A03 compound treatment 0.314 -0.00812 -0.32 0.324 1.88E-4 0.0 -0.2231 -0.6984 2068745 IFLab1_005987 CN(C)CCNC(=O)c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A04 compound treatment 0.352 0.0299 1.17 0.316 -0.00781 -0.16 0.715 0.6029 2068746 IFLab1_005988 Cn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A05 compound treatment 0.312 -0.0101 -0.4 0.311 -0.0128 -0.27 -0.4711 -0.9815 2068747 IFLab1_005989 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A06 compound treatment 0.313 -0.00912 -0.36 0.339 0.0152 0.32 -0.029 -0.0604 2068748 IFLab1_005990 Cc1cc(C)c(cc1C)S(=O)(=O)N2CCSC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A07 compound treatment 0.31 -0.0121 -0.48 0.317 -0.00681 -0.14 -0.4379 -0.8801 2068749 IFLab1_005991 CCC(=O)Nc1ccc(cc1)c2cn3cccc(C)c3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A08 compound treatment 0.315 -0.00712 -0.28 0.316 -0.00781 -0.16 -0.3137 -0.9671 1364444 IFLab1_005992 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A09 compound treatment 0.341 0.0189 0.74 0.315 -0.00881 -0.18 0.3944 0.5157 2068750 IFLab1_005993 NC(=O)CSc1nnc(c2cccs2)n1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A10 compound treatment 0.328 0.00588 0.23 0.342 0.0182 0.38 0.4325 0.9714 2068751 IFLab1_005994 O=S(=O)(NC1CCCCC1n2cc(nn2)c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A11 compound treatment 0.325 0.00288 0.11 0.319 -0.00481 -0.1 0.0087 0.0576 2068752 IFLab1_005995 CN(C)C(=O)c1cn(nc1c2cc3ccccc3o2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A12 compound treatment 0.322 -1.25E-4 0.0 0.322 -0.00181 -0.04 -0.0303 -0.7921 2068753 IFLab1_005996 O=C(NCCC1=CCCCC1)/C=C/c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A13 compound treatment 0.36 0.0379 1.49 0.321 -0.00281 -0.06 1.0114 0.6786 2068754 IFLab1_005997 c1ccc(cc1)n2nnnc2c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A14 compound treatment 0.312 -0.0101 -0.4 0.329 0.00519 0.11 -0.2047 -0.4962 1104608 IFLab1_005998 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccccc2)N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A15 compound treatment 0.317 -0.00512 -0.2 0.313 -0.0108 -0.23 -0.3025 -0.9983 2068755 IFLab1_005999 CCOc1ccc(cc1)n2nnnc2c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A16 compound treatment 0.353 0.0309 1.21 0.323 -8.12E-4 -0.02 0.8464 0.6971 2068756 IFLab1_006000 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2cccs2)c3cccc(OCC=C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A17 compound treatment 0.327 0.00488 0.19 0.331 0.00719 0.15 0.2419 0.9928 2068757 IFLab1_006001 Cc1ccc2[nH]c(SCc3ccccc3)nc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A18 compound treatment 0.738 0.416 16.35 0.719 0.395 8.27 17.4098 0.9501 2068758 IFLab1_006002 CCN(CC)CC1=C/C(=N/O)/c2cccnc2C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A19 compound treatment 0.344 0.0219 0.86 0.312 -0.0118 -0.25 0.4334 0.4843 2068759 IFLab1_006003 Cc1cccc(OCCn2cnc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A20 compound treatment 0.321 -0.00112 -0.04 0.353 0.0292 0.61 0.4006 0.6542 2068760 IFLab1_006004 CN(C)C(CC(=O)Nc1cc(C)cc(C)c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A21 compound treatment 0.317 -0.00512 -0.2 0.321 -0.00281 -0.06 -0.1841 -0.877 2068761 IFLab1_006005 CC(C)N1C(=O)/C(=C/c2cccc(Cl)c2Cl)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A22 compound treatment 0.361 0.0389 1.53 0.341 0.0172 0.36 1.3351 0.8503 2068762 IFLab1_006006 COc1cc(/C=N/S(=O)(=O)c2ccccc2)cc(OC)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A23 mock treatment 0.316 -0.00612 -0.24 0.313 -0.0108 -0.23 -0.3303 -0.9995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 A24 positive control 0.079 -0.243 -9.56 0.079 -0.245 -5.12 -10.3819 -0.9573 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B01 compound treatment 0.409 0.0869 3.42 0.396 0.0722 1.51 3.4835 0.9327 2068763 IFLab1_006007 Cc1sc2nc(Nc3ccc(cc3)S(=O)(=O)N)sc(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B02 compound treatment 0.298 -0.0241 -0.95 0.307 -0.0168 -0.35 -0.9195 -0.9089 1541550 IFLab1_006008 CCCCc1ccc(NS(=O)(=O)c2cccs2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B03 compound treatment 0.332 0.00988 0.39 0.323 -8.12E-4 -0.02 0.2625 0.6755 2068764 IFLab1_006009 N(/C=N\c1nccs1)c2nccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B04 compound treatment 0.354 0.0319 1.25 0.345 0.0212 0.44 1.1997 0.9025 2068765 IFLab1_006010 CCOc1cc(/C=C\2/SC(=S)N(C2=O)c3ccc4OCOc4c3)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B05 compound treatment 0.315 -0.00712 -0.28 0.321 -0.00281 -0.06 -0.2397 -0.8374 2068766 IFLab1_006011 Cc1sc2nc(SCCC(=O)NC3CCCCC3)[nH]c(=O)c2c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B06 compound treatment 0.356 0.0339 1.33 0.347 0.0232 0.49 1.2849 0.9064 2068767 IFLab1_006012 COc1ccccc1/C=C/2\SC(=S)N(C2=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B07 compound treatment 0.349 0.0269 1.06 0.341 0.0172 0.36 1.0015 0.8972 2068768 IFLab1_006013 Cc1ccc(cc1)c2cnnn2c3ccc(cc3)C(=O)COC(=O)c4ccccc4F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B08 compound treatment 0.327 0.00488 0.19 0.321 -0.00281 -0.06 0.0939 0.4684 2068769 IFLab1_006014 COc1ccc(Cn2c(=O)oc3ccc(C)cc23)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B09 compound treatment 0.328 0.00588 0.23 0.324 1.88E-4 0.0 0.1661 0.719 1630178 IFLab1_006015 COC(=O)Cc1c(c2ccccc2)c3cc(C)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B10 compound treatment 0.337 0.0149 0.58 0.332 0.00819 0.17 0.5347 0.8774 2068770 IFLab1_006016 Cc1ccc(NS(=O)(=O)C(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B11 compound treatment 0.36 0.0379 1.49 0.345 0.0212 0.44 1.3665 0.8795 1633075 IFLab1_006017 Cc1ccc2[nH]c(=O)c(CNS(=O)(=O)c3ccccc3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B12 compound treatment 0.32 -0.00212 -0.08 0.327 0.00319 0.07 -0.0119 -0.1114 2068771 IFLab1_006018 CC1C/C(=C\c2cccnc2)/C(=O)\C(=C\c3cccnc3)\C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B13 compound treatment 0.335 0.0129 0.51 0.323 -8.12E-4 -0.02 0.3459 0.683 2068772 IFLab1_006019 COCCn1cnc2cc(C)c(C)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B14 compound treatment 0.323 8.75E-4 0.03 0.325 0.00119 0.02 0.0419 0.9873 1865121 IFLab1_006020 COc1ccc(OCC(O)CNC(C)C)c(c1)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B15 compound treatment 0.337 0.0149 0.58 0.335 0.0112 0.23 0.5791 0.9192 2068773 IFLab1_006021 CC(=O)NCCCc1nc2ccccc2n1Cc3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B16 compound treatment 0.336 0.0139 0.55 0.322 -0.00181 -0.04 0.3589 0.6564 2068774 IFLab1_006022 COc1ccc(CCNC(=O)c2csc3CCCCc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B17 compound treatment 0.334 0.0119 0.47 0.339 0.0152 0.32 0.5549 0.9824 2068775 IFLab1_006023 CN(C)CCNc1nc2ccccc2n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B18 compound treatment 0.339 0.0169 0.66 0.339 0.0152 0.32 0.6939 0.9432 2068776 IFLab1_006024 FC(F)(F)c1ccc(NC(=O)/C=C/c2ccco2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B19 compound treatment 0.337 0.0149 0.58 0.321 -0.00281 -0.06 0.3719 0.6328 2068777 IFLab1_006025 Cc1cccc(OCC(O)CN2CCCCCC2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B20 compound treatment 0.331 0.00888 0.35 0.326 0.00219 0.05 0.2791 0.7931 2068778 IFLab1_006026 OCCN1CCN(CC1)c2nc(c3ccccc3)c4cc(Br)ccc4n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B21 compound treatment 0.337 0.0149 0.58 0.333 0.00919 0.19 0.5495 0.8926 1479148 IFLab1_006027 C(N1CCOCC1)c2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B22 compound treatment 0.293 -0.0291 -1.15 0.292 -0.0318 -0.67 -1.2805 -0.9667 2068779 IFLab1_006028 Oc1c(Br)cc(/C=[N+](\[O-])/c2ccccc2)cc1Br 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B23 mock treatment 0.325 0.00288 0.11 0.327 0.00319 0.07 0.1271 0.9683 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 B24 positive control 0.078 -0.244 -9.6 0.078 -0.246 -5.14 -10.4245 -0.9573 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C01 compound treatment 0.331 0.00888 0.35 0.331 0.00719 0.15 0.3531 0.9292 2068780 IFLab1_006029 COc1cc(C)c(Cl)c(C)c1S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C02 compound treatment 0.334 0.0119 0.47 0.315 -0.00881 -0.18 0.1997 0.3979 2068781 IFLab1_006030 c1csc(c1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C03 compound treatment 0.332 0.00988 0.39 0.318 -0.00581 -0.12 0.1885 0.4634 2068782 IFLab1_006031 CN(CC(O)Cn1c2ccccc2c3ccccc13)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C04 compound treatment 0.317 -0.00512 -0.2 0.327 0.00319 0.07 -0.0953 -0.4491 2068783 IFLab1_006032 CC(C)n1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C05 compound treatment 0.318 -0.00412 -0.16 0.326 0.00219 0.05 -0.0823 -0.4884 2068784 IFLab1_006033 CN(C)S(=O)(=O)Nc1ccc(N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C06 compound treatment 0.324 0.00188 0.07 0.324 1.88E-4 0.0 0.0549 0.7437 2068785 IFLab1_006034 CC1SCCN1S(=O)(=O)c2c(C)cc(C)cc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C07 compound treatment 0.345 0.0229 0.9 0.343 0.0192 0.4 0.9199 0.9339 2068786 IFLab1_006035 CC(C)CC(=O)Nc1ccc(cc1)c2cn3cccc(C)c3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C08 compound treatment 0.338 0.0159 0.62 0.328 0.00419 0.09 0.5033 0.7985 2068787 IFLab1_006036 Cc1ccc(s1)S(=O)(=O)NCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C09 compound treatment 0.335 0.0129 0.51 0.324 1.88E-4 0.0 0.3607 0.7126 2068788 IFLab1_006037 COC(=O)CSc1nnc(c2cccs2)n1c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C10 compound treatment 0.33 0.00788 0.31 0.324 1.88E-4 0.0 0.2217 0.716 1572783 IFLab1_006038 CC1(C)C(CCC1(C)C(=O)O)C(=O)N2CCc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C11 compound treatment 0.321 -0.00112 -0.04 0.323 -8.12E-4 -0.02 -0.0433 -0.9137 2068789 IFLab1_006039 COC(=O)CNC(=O)c1cn(nc1c2ccc(F)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C12 compound treatment 0.382 0.0599 2.35 0.387 0.0632 1.32 2.5996 0.9628 2068790 IFLab1_006040 Cc1sc(NC(=O)/C=C/c2ccco2)c(C(=O)N)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C13 compound treatment 0.34 0.0179 0.7 0.33 0.00619 0.13 0.5885 0.8235 2068791 IFLab1_006041 c1ccc(cc1)n2nnnc2c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C14 compound treatment 0.32 -0.00212 -0.08 0.321 -0.00281 -0.06 -0.1007 -0.9853 2068792 IFLab1_006042 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C15 compound treatment 0.337 0.0149 0.58 0.325 0.00119 0.02 0.4311 0.7365 2068793 IFLab1_006043 c1ccc(cc1)n2nnnc2c3nc4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C16 compound treatment 0.33 0.00788 0.31 0.331 0.00719 0.15 0.3253 0.945 2068794 IFLab1_006044 COc1cccc(c1)C(=O)C2=C(O)C(=O)N(CCN(C)C)C2c3ccc(cc3)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C17 compound treatment 0.325 0.00288 0.11 0.337 0.0132 0.28 0.2751 0.9224 2068795 IFLab1_006045 CC(O)c1nc2ccccc2n1C/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C18 compound treatment 0.638 0.316 12.42 0.625 0.301 6.3 13.2387 0.9506 2068796 IFLab1_006046 O/N=C\1/C=C(CN2CCOCC2)C(=O)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C19 compound treatment 0.332 0.00988 0.39 0.323 -8.12E-4 -0.02 0.2625 0.6755 2068797 IFLab1_006047 COCCn1c(nc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C20 compound treatment 0.33 0.00788 0.31 0.321 -0.00281 -0.06 0.1773 0.5626 2068798 IFLab1_006048 CCN(CC)CC(O)Cn1c2CCCCc2c3cc(C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C21 compound treatment 0.336 0.0139 0.55 0.322 -0.00181 -0.04 0.3589 0.6564 2068799 IFLab1_006049 CC(C)N1C(=O)/C(=C/c2ccc(Br)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C22 compound treatment 0.344 0.0219 0.86 0.343 0.0192 0.4 0.8921 0.9398 2068800 IFLab1_006050 COc1ccc(OC)c(NC(=O)CC2Sc3ccccc3NC2=O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C23 mock treatment 0.32 -0.00212 -0.08 0.321 -0.00281 -0.06 -0.1007 -0.9853 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 C24 positive control 0.079 -0.243 -9.56 0.08 -0.244 -5.1 -10.3671 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D01 compound treatment 0.345 0.0229 0.9 0.336 0.0122 0.26 0.8163 0.8732 2068801 IFLab1_006051 Cc1cccc(c1)c2nc3scc(c4ccccc4)n3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D02 compound treatment 0.316 -0.00612 -0.24 0.312 -0.0118 -0.25 -0.3451 -0.9999 2068802 IFLab1_006052 Clc1ccc(Cl)c(NS(=O)(=O)c2cccs2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D03 compound treatment 0.254 -0.0681 -2.68 0.261 -0.0628 -1.31 -2.8235 -0.9463 2068803 IFLab1_006053 CN1C(=O)/C(=C\c2ccc(o2)c3ccccc3)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D04 compound treatment 0.37 0.0479 1.88 0.384 0.0602 1.26 2.2216 0.9809 2068804 IFLab1_006054 COc1cc(/C=C\2/SC(=S)N(C2=O)c3ccc4ccccc4c3)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D05 compound treatment 0.334 0.0119 0.47 0.315 -0.00881 -0.18 0.1997 0.3979 1013635 IFLab1_006055 OC(=O)C1Cc2ccccc2CN1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D06 compound treatment 0.364 0.0419 1.65 0.34 0.0162 0.34 1.4037 0.8351 2068805 IFLab1_006056 COc1ccccc1/C=C/2\SC(=O)N(C2=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D07 compound treatment 0.359 0.0369 1.45 0.361 0.0372 0.78 1.5755 0.9574 2068806 IFLab1_006057 CCN1C(=O)/C(=C\c2ccc(NC(=O)C(F)(F)F)cc2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D08 compound treatment 0.333 0.0109 0.43 0.323 -8.12E-4 -0.02 0.2903 0.6785 1870189 IFLab1_006058 CC(C)C(NC(=O)c1cc2ccccc2cc1O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D09 compound treatment 0.337 0.0149 0.58 0.322 -0.00181 -0.04 0.3867 0.6599 1231001 IFLab1_006059 CCOC(=O)Cc1c(c2ccccc2)c3cc(C)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D10 compound treatment 0.345 0.0229 0.9 0.323 -8.12E-4 -0.02 0.6239 0.6936 2068807 IFLab1_006060 Cc1ccccc1OCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D11 compound treatment 0.348 0.0259 1.02 0.344 0.0202 0.42 1.0181 0.9242 2068808 IFLab1_006061 Cc1ccc(cc1)N2C(=O)CC(Sc3ccccc3C(=O)N4CCOCC4)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D12 compound treatment 0.332 0.00988 0.39 0.333 0.00919 0.19 0.4105 0.9475 2068809 IFLab1_006062 Cc1ccnc2ccc(SC(F)(F)F)cc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D13 compound treatment 0.33 0.00788 0.31 0.328 0.00419 0.09 0.2809 0.8729 1033861 IFLab1_006063 COCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D14 compound treatment 0.337 0.0149 0.58 0.33 0.00619 0.13 0.5051 0.8432 2068810 IFLab1_006064 Cc1ccc(OCC(O)CN)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D15 compound treatment 0.337 0.0149 0.58 0.329 0.00519 0.11 0.4903 0.8243 2068811 IFLab1_006065 CC(=O)NCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D16 compound treatment 0.336 0.0139 0.55 0.323 -8.12E-4 -0.02 0.3737 0.6847 2068812 IFLab1_006066 COc1ccc(cc1)C2C3C(SC(=C2C#N)N)C(=O)N(C3=O)c4ccc(C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D17 compound treatment 0.334 0.0119 0.47 0.332 0.00819 0.17 0.4513 0.9074 2068813 IFLab1_006067 CCN(CC)CCCNc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D18 compound treatment 0.337 0.0149 0.58 0.338 0.0142 0.3 0.6235 0.9506 2068814 IFLab1_006068 O=C(NCCc1ccccc1)/C=C/c2ccco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D19 compound treatment 0.334 0.0119 0.47 0.335 0.0112 0.23 0.4957 0.949 2068815 IFLab1_006069 Cc1cccc(OCC(O)CN2CCN(Cc3ccccc3)CC2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D20 compound treatment 0.333 0.0109 0.43 0.337 0.0132 0.28 0.4975 0.9776 2068816 IFLab1_006070 COc1cc(N)n(n1)S(=O)(=O)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D21 compound treatment 0.335 0.0129 0.51 0.327 0.00319 0.07 0.4051 0.7934 2068817 IFLab1_006071 COC(=O)c1cccnc1c2nc3ccccc3s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D22 compound treatment 0.339 0.0169 0.66 0.34 0.0162 0.34 0.7087 0.9513 2068818 IFLab1_006072 COc1cc(/C=[N+](\[O-])/c2ccccc2)cc(OC)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D23 mock treatment 0.322 -1.25E-4 0.0 0.318 -0.00581 -0.12 -0.0895 -0.7351 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 D24 positive control 0.08 -0.242 -9.52 0.081 -0.243 -5.08 -10.3245 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E01 compound treatment 0.339 0.0169 0.66 0.326 0.00219 0.05 0.5015 0.7541 2068819 IFLab1_006073 COc1ccc(cc1C)S(=O)(=O)n2ccc(C)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E02 compound treatment 0.33 0.00788 0.31 0.31 -0.0138 -0.29 0.0146 0.0344 2068820 IFLab1_006074 CCCn1c(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E03 compound treatment 0.329 0.00688 0.27 0.317 -0.00681 -0.14 0.0903 0.2956 2068821 IFLab1_006075 CS(=O)(=O)NCC(O)Cn1c2ccccc2c3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E04 compound treatment 0.333 0.0109 0.43 0.33 0.00619 0.13 0.3939 0.8817 1531370 IFLab1_006076 CC(C)CCOc1ccc(CN)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E05 compound treatment 0.326 0.00388 0.15 0.327 0.00319 0.07 0.1549 0.9313 1012680 IFLab1_006077 O=S(=O)(N1CCCCC1)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E06 compound treatment 0.334 0.0119 0.47 0.339 0.0152 0.32 0.5549 0.9824 2068822 IFLab1_006078 Cc1ccn2cc(nc2c1)c3cccc(NS(=O)(=O)C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E07 compound treatment 0.357 0.0349 1.37 0.349 0.0252 0.53 1.3423 0.9137 1112848 IFLab1_006079 Oc1nc2ccccc2nc1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E08 compound treatment 0.349 0.0269 1.06 0.333 0.00919 0.19 0.8831 0.8223 1141016 IFLab1_006080 O=S(=O)(NCCc1ccccn1)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E09 compound treatment 0.342 0.0199 0.78 0.336 0.0122 0.26 0.7329 0.8916 2068823 IFLab1_006081 COc1ccc(cc1OC)c2nnc(SCC(=O)c3ccccc3)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E10 compound treatment 0.338 0.0159 0.62 0.324 1.88E-4 0.0 0.4441 0.7115 2068824 IFLab1_006082 COC(=O)C1=C(N)OC2=C(C1c3ccccc3)C(=O)CC(C)(C)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E11 compound treatment 0.338 0.0159 0.62 0.338 0.0142 0.3 0.6513 0.9423 2068825 IFLab1_006083 OC(=O)CNC(=O)c1cn(nc1c2ccc(Cl)s2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E12 compound treatment 0.359 0.0369 1.45 0.345 0.0212 0.44 1.3387 0.883 2068826 IFLab1_006084 COc1ccc(/C=C/C(=O)Nc2sc(C)c(C)c2C(=O)N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E13 compound treatment 0.339 0.0169 0.66 0.334 0.0102 0.21 0.6199 0.8895 2068827 IFLab1_006085 Cc1ccc(cc1)n2nnnc2c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E14 compound treatment 0.327 0.00488 0.19 0.328 0.00419 0.09 0.1975 0.9371 1259598 IFLab1_006086 CCCC1=C(C(C(=C(N)O1)C#N)c2ccccc2)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E15 compound treatment 0.353 0.0309 1.21 0.333 0.00919 0.19 0.9943 0.809 2068828 IFLab1_006087 Clc1cc(Cn2cnc3ccccc23)c4OCOCc4c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E16 compound treatment 0.342 0.0199 0.78 0.329 0.00519 0.11 0.6293 0.7977 2068829 IFLab1_006088 COc1cccc(c1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3)c4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E17 compound treatment 0.338 0.0159 0.62 0.315 -0.00881 -0.18 0.311 0.4778 2068830 IFLab1_006089 Cn1c(CC(C)(C)C)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E18 compound treatment 0.549 0.227 8.92 0.535 0.211 4.42 9.4325 0.9475 2068831 IFLab1_006090 COC(=O)c1ccccc1c2ccc(/C=C/3\SC(=O)NC3=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E19 compound treatment 0.337 0.0149 0.58 0.32 -0.00381 -0.08 0.3571 0.605 2068832 IFLab1_006091 COCc1nc2ccccc2n1Cc3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E20 compound treatment 0.331 0.00888 0.35 0.336 0.0122 0.26 0.4271 0.9881 2068833 IFLab1_006092 CCC(CO)NCC(O)Cn1c2CCCCc2c3cc(C)ccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E21 compound treatment 0.346 0.0239 0.94 0.341 0.0172 0.36 0.9181 0.9133 2068834 IFLab1_006093 COc1cc(/C=C/2\SC(=S)N(C(C)C)C2=O)ccc1OCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E22 compound treatment 0.329 0.00688 0.27 0.323 -8.12E-4 -0.02 0.1791 0.6613 2068835 IFLab1_006094 CCOc1cc(/C=N/S(=O)(=O)c2cccs2)cc(Br)c1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E23 mock treatment 0.319 -0.00312 -0.12 0.321 -0.00281 -0.06 -0.1285 -0.9432 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 E24 positive control 0.081 -0.241 -9.48 0.082 -0.242 -5.06 -10.2819 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F01 compound treatment 0.338 0.0159 0.62 0.332 0.00819 0.17 0.5625 0.8691 2068836 IFLab1_006095 CSc1nnc(COc2ccccc2)n1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F02 compound treatment 0.321 -0.00112 -0.04 0.321 -0.00281 -0.06 -0.0729 -0.9901 2068837 IFLab1_006096 CCOc1ccccc1N2C(=O)/C(=C\c3cccs3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F03 compound treatment 0.325 0.00288 0.11 0.32 -0.00381 -0.08 0.0235 0.17 2068838 IFLab1_006097 CCN(CC)C(=O)/C=C/c1ccc(o1)c2cc(Cl)ccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F04 compound treatment 0.376 0.0539 2.12 0.369 0.0452 0.95 2.1665 0.9339 2068839 IFLab1_006098 COc1cc(/C=C\2/SC(=O)N(C2=O)c3ccc(C)cc3)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F05 compound treatment 0.307 -0.0151 -0.59 0.311 -0.0128 -0.27 -0.6101 -0.9353 2068840 IFLab1_006099 COc1ccc(CCNCC2CCCO2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F06 compound treatment 0.332 0.00988 0.39 0.319 -0.00481 -0.1 0.2033 0.5069 2068841 IFLab1_006100 Clc1cc(Cl)cc(c1)N2C(=O)/C(=C/c3cccs3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F07 compound treatment 0.34 0.0179 0.7 0.333 0.00919 0.19 0.6329 0.8686 1703775 IFLab1_006101 Brc1ccc(cc1)c2cn3ccccc3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F08 compound treatment 0.327 0.00488 0.19 0.323 -8.12E-4 -0.02 0.1235 0.6419 1559763 IFLab1_006102 CCCN(CCC)C(=O)c1cc2ccccc2cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F09 compound treatment 0.344 0.0219 0.86 0.318 -0.00581 -0.12 0.5222 0.6011 1785241 IFLab1_006103 Cc1ccc2[nH]c(=O)c(CC(=O)O)c(c3ccccc3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F10 compound treatment 0.337 0.0149 0.58 0.334 0.0102 0.21 0.5643 0.9065 2068842 IFLab1_006104 COc1ccccc1OCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F11 compound treatment 0.357 0.0349 1.37 0.336 0.0122 0.26 1.1499 0.8245 2068843 IFLab1_006105 Fc1ccc(CN2C(=O)S/C(=C\C(=O)Nc3nccs3)/C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F12 compound treatment 0.335 0.0129 0.51 0.316 -0.00781 -0.16 0.2423 0.4556 2068844 IFLab1_006106 Clc1ccccc1c2nnc(o2)c3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F13 compound treatment 0.345 0.0229 0.9 0.33 0.00619 0.13 0.7275 0.8007 2068845 IFLab1_006107 COCc1nc2ccccc2n1Cc3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F14 compound treatment 0.359 0.0369 1.45 0.329 0.00519 0.11 1.102 0.7579 2068846 IFLab1_006108 Cc1ccc(CC2SC(=N)NC2=O)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F15 compound treatment 0.343 0.0209 0.82 0.316 -0.00781 -0.16 0.4648 0.5553 1705662 IFLab1_006109 C1CNC(C1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F16 compound treatment 0.351 0.0289 1.14 0.336 0.0122 0.26 0.9831 0.8449 2068847 IFLab1_006110 Cc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F17 compound treatment 0.332 0.00988 0.39 0.325 0.00119 0.02 0.2921 0.7508 2068848 IFLab1_006111 COc1ccc(OC)c(NS(=O)(=O)c2cccs2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F18 compound treatment 0.308 -0.0141 -0.56 0.285 -0.0388 -0.81 -0.967 -0.9828 2068849 IFLab1_006112 Oc1ccc(O)c(Sc2nnnn2c3ccccc3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F19 compound treatment 0.341 0.0189 0.74 0.338 0.0142 0.3 0.7347 0.9192 2068850 IFLab1_006113 CC(C)NCC(O)COc1cc(C)cc(C)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F20 compound treatment 0.33 0.00788 0.31 0.34 0.0162 0.34 0.4585 0.999 2068851 IFLab1_006114 O=C1CN(c2ccccc2N1)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F21 compound treatment 0.336 0.0139 0.55 0.325 0.00119 0.02 0.4033 0.7386 1415204 IFLab1_006115 Brc1c(nc2ccccn12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F22 compound treatment 0.342 0.0199 0.78 0.32 -0.00381 -0.08 0.4962 0.6316 2068852 IFLab1_006116 CCc1cc(C(=O)OC)c(NC(=O)/C=C/C(=O)O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F23 mock treatment 0.323 8.75E-4 0.03 0.325 0.00119 0.02 0.0419 0.9873 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 F24 positive control 0.081 -0.241 -9.48 0.084 -0.24 -5.02 -10.2523 -0.9558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G01 compound treatment 0.332 0.00988 0.39 0.326 0.00219 0.05 0.3069 0.785 2068853 IFLab1_006117 COc1cc(ccc1Cl)S(=O)(=O)n2ccc(C)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G02 compound treatment 0.319 -0.00312 -0.12 0.314 -0.00981 -0.21 -0.2321 -0.9699 2068854 IFLab1_006118 CC(C)Cn1c(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G03 compound treatment 0.325 0.00288 0.11 0.311 -0.0128 -0.27 -0.1097 -0.3769 1146217 IFLab1_006119 Clc1c(sc2cc(Cl)ccc12)C(=O)NCCN3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G04 compound treatment 0.319 -0.00312 -0.12 0.321 -0.00281 -0.06 -0.1285 -0.9432 2068855 IFLab1_006120 CCOC(=O)Cn1c2ccc(Cl)cc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G05 compound treatment 0.316 -0.00612 -0.24 0.314 -0.00981 -0.21 -0.3155 -0.9969 1013038 IFLab1_006121 Cc1ccccc1NS(=O)(=O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G06 compound treatment 0.303 -0.0191 -0.75 0.31 -0.0138 -0.29 -0.7361 -0.9137 2068856 IFLab1_006122 Clc1ccc(s1)S(=O)(=O)NN2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G07 compound treatment 0.301 -0.0211 -0.83 0.278 -0.0458 -0.96 -1.2652 -0.9974 2068857 IFLab1_006123 Fc1ccc(NC(=O)CN2C(=O)/C(=C\C=C\c3ccccc3)/SC2=S)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G08 compound treatment 0.318 -0.00412 -0.16 0.321 -0.00281 -0.06 -0.1563 -0.9059 2068858 IFLab1_006124 Cc1nc2ccccc2cc1C(=O)NCc3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G09 compound treatment 0.341 0.0189 0.74 0.324 1.88E-4 0.0 0.5275 0.7108 2068859 IFLab1_006125 Clc1ccc(cc1)c2csc3ncnn23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G10 compound treatment 0.343 0.0209 0.82 0.323 -8.12E-4 -0.02 0.5683 0.6923 2068860 IFLab1_006126 NC1=C(C#N)C(c2cccnc2)c3ccc(N)cc3O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G11 compound treatment 0.318 -0.00412 -0.16 0.316 -0.00781 -0.16 -0.2303 -1.0 2068861 IFLab1_006127 COc1ccccc1N(C)S(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G12 compound treatment 0.33 0.00788 0.31 0.321 -0.00281 -0.06 0.1773 0.5626 2068862 IFLab1_006128 O=C(/C=C/c1ccccc1)N2CCNC(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G13 compound treatment 0.335 0.0129 0.51 0.331 0.00719 0.15 0.4643 0.8792 2068863 IFLab1_006129 CCOc1ccc(cc1)n2nnnc2c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G14 compound treatment 0.33 0.00788 0.31 0.34 0.0162 0.34 0.4585 0.999 1650810 IFLab1_006130 COc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)OCc3ccccc3)C)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G15 compound treatment 0.331 0.00888 0.35 0.324 1.88E-4 0.0 0.2495 0.715 2068864 IFLab1_006131 ClC1(Cl)CC1Cn2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G16 compound treatment 0.499 0.177 6.95 0.399 0.0752 1.57 6.03 0.8457 2068865 IFLab1_006132 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2cc3ccccc3o2)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G17 compound treatment 0.336 0.0139 0.55 0.318 -0.00581 -0.12 0.2997 0.5363 1147748 IFLab1_006133 Cc1cccc(OCCn2c(CO)nc3ccccc23)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G18 compound treatment 0.331 0.00888 0.35 0.32 -0.00381 -0.08 0.1903 0.5317 1082165 IFLab1_006134 CC1(C)OC(=O)N(C1=C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G19 compound treatment 0.328 0.00588 0.23 0.312 -0.0118 -0.25 -0.0115 -0.0339 2068866 IFLab1_006135 OCc1nc2ccccc2n1CC3CC3(Cl)Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G20 compound treatment 0.311 -0.0111 -0.44 0.317 -0.00681 -0.14 -0.4101 -0.8914 2068867 IFLab1_006136 CC1CCCCN1CC(O)Cn2c(C)c(C)c3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G21 compound treatment 0.321 -0.00112 -0.04 0.314 -0.00981 -0.21 -0.1765 -0.8402 2068868 IFLab1_006137 CC(C)N1C(=O)/C(=C/c2ccc(cc2)N(C)C)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G22 compound treatment 0.318 -0.00412 -0.16 0.303 -0.0208 -0.44 -0.4226 -0.9094 2068869 IFLab1_006138 CC(NC(=O)CC1Nc2cc(C)c(C)cc2NC1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G23 mock treatment 0.318 -0.00412 -0.16 0.316 -0.00781 -0.16 -0.2303 -1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 G24 positive control 0.081 -0.241 -9.48 0.083 -0.241 -5.04 -10.2671 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H01 compound treatment 0.334 0.0119 0.47 0.335 0.0112 0.23 0.4957 0.949 2068870 IFLab1_006139 CCn1c(COc2ccc(Cl)c3cccnc23)nnc1SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H02 compound treatment 0.345 0.0229 0.9 0.338 0.0142 0.3 0.8459 0.8931 2068871 IFLab1_006140 Cc1ccc(/N=C/2\NC(=O)\C(=C/c3cccs3)\S2)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H03 compound treatment 0.335 0.0129 0.51 0.332 0.00819 0.17 0.4791 0.8965 2068872 IFLab1_006141 Clc1ccc(Cl)c(c1)c2ccc(/C=C/C(=O)N3CCOCC3)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H04 compound treatment 0.526 0.204 8.02 0.515 0.191 4.0 8.4972 0.9485 2068873 IFLab1_006142 CCC(N1C(=O)/C(=C\C(=C\c2ccccc2)\C)/SC1=S)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H05 compound treatment 0.323 8.75E-4 0.03 0.329 0.00519 0.11 0.1011 0.8877 1249854 IFLab1_006143 COc1ccc(CNCC2CCCO2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H06 compound treatment 0.32 -0.00212 -0.08 0.335 0.0112 0.23 0.1065 0.4283 2068874 IFLab1_006144 Clc1ccc(cc1Cl)N2C(=O)/C(=C/c3cccs3)/SC2=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H07 compound treatment 0.337 0.0149 0.58 0.334 0.0102 0.21 0.5643 0.9065 2068875 IFLab1_006145 Cc1ccn2cc(nc2c1)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H08 compound treatment 0.322 -1.25E-4 0.0 0.318 -0.00581 -0.12 -0.0895 -0.7351 2068876 IFLab1_006146 FC(F)(F)S(=O)(=O)Nc1ccc(Br)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H09 compound treatment 0.339 0.0169 0.66 0.33 0.00619 0.13 0.5607 0.8295 2068877 IFLab1_006147 Brc1ccc2[nH]c(=O)c(CN3CCCCC3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H10 compound treatment 0.337 0.0149 0.58 0.324 1.88E-4 0.0 0.4163 0.7118 1066538 IFLab1_006148 Cc1ccc(OCCC(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H11 compound treatment 0.339 0.0169 0.66 0.339 0.0152 0.32 0.6939 0.9432 2068878 IFLab1_006149 COc1ccc2cc(sc(=O)c2c1OC)C(=O)N3CCOCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H12 compound treatment 0.33 0.00788 0.31 0.316 -0.00781 -0.16 0.1033 0.2951 2068879 IFLab1_006150 Brc1cccc(c1)c2nnco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H13 compound treatment 0.332 0.00988 0.39 0.323 -8.12E-4 -0.02 0.2625 0.6755 2068880 IFLab1_006151 COCc1nc2ccccc2n1CC(=O)N(C(C)C)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H14 compound treatment 0.32 -0.00212 -0.08 0.322 -0.00181 -0.04 -0.0859 -0.9362 2068881 IFLab1_006152 CCOC(=O)c1ccc(CC2SC(=N)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H15 compound treatment 0.333 0.0109 0.43 0.322 -0.00181 -0.04 0.2755 0.6419 1920651 IFLab1_006153 Cc1ccc(cc1)c2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H16 compound treatment 0.34 0.0179 0.7 0.323 -8.12E-4 -0.02 0.4849 0.6898 2068882 IFLab1_006154 COc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H17 compound treatment 0.335 0.0129 0.51 0.325 0.00119 0.02 0.3755 0.7409 2068883 IFLab1_006155 CN(Cc1ccccc1)S(=O)(=O)c2ccc(C)c(c2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H18 compound treatment 0.334 0.0119 0.47 0.312 -0.0118 -0.25 0.1554 0.2941 2068884 IFLab1_006156 C(=C/c1ccccc1)\c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H19 compound treatment 0.334 0.0119 0.47 0.334 0.0102 0.21 0.4809 0.9369 2068885 IFLab1_006157 CC1CC(CC(C)(C)C1)OCC(O)CN2CCN(CC2)c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H20 compound treatment 0.335 0.0129 0.51 0.34 0.0162 0.34 0.5975 0.9809 2068886 IFLab1_006158 CCCNS(=O)(=O)c1ccc(NC(=O)c2ccncc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H21 compound treatment 0.33 0.00788 0.31 0.333 0.00919 0.19 0.3549 0.9737 2068887 IFLab1_006159 Cc1cccc2nc(CSc3nncn3c4ccccc4)cn12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H22 compound treatment 0.333 0.0109 0.43 0.322 -0.00181 -0.04 0.2755 0.6419 2068888 IFLab1_006160 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1C4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H23 mock treatment 0.322 -1.25E-4 0.0 0.321 -0.00281 -0.06 -0.0451 -0.7635 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 H24 positive control 0.083 -0.239 -9.4 0.084 -0.24 -5.02 -10.1967 -0.9568 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I01 compound treatment 0.343 0.0209 0.82 0.335 0.0112 0.23 0.7459 0.8739 2068889 IFLab1_006161 CCOc1ccc(cc1)S(=O)(=O)n2ccc(C)n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I02 compound treatment 0.334 0.0119 0.47 0.319 -0.00481 -0.1 0.2589 0.5421 2068890 IFLab1_006162 CCn1c(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I03 compound treatment 0.35 0.0279 1.1 0.344 0.0202 0.42 1.0737 0.9141 2068891 IFLab1_006163 CCOC(=O)c1ccc2nc(nc(Cl)c2c1)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I04 compound treatment 0.331 0.00888 0.35 0.32 -0.00381 -0.08 0.1903 0.5317 2068892 IFLab1_006164 COc1ccc(Cn2c(=O)oc3ccccc23)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I05 compound treatment 0.341 0.0189 0.74 0.322 -0.00181 -0.04 0.4979 0.6701 1013041 IFLab1_006165 COc1ccc(NS(=O)(=O)N2CCCCC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I06 compound treatment 0.334 0.0119 0.47 0.332 0.00819 0.17 0.4513 0.9074 2068893 IFLab1_006166 CN(c1ccccc1)S(=O)(=O)c2ccc(C)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I07 compound treatment 0.383 0.0609 2.39 0.393 0.0692 1.45 2.7162 0.971 2068894 IFLab1_006167 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(CCC(=O)Nc3nc(C)cs3)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I08 compound treatment 0.315 -0.00712 -0.28 0.342 0.0182 0.38 0.071 0.1503 2068895 IFLab1_006168 Cc1nc2ccccc2cc1C(=O)NCc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I09 compound treatment 0.353 0.0309 1.21 0.344 0.0202 0.42 1.1571 0.9002 2068896 IFLab1_006169 c1sc2nc(nn2c1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I10 compound treatment 0.339 0.0169 0.66 0.337 0.0132 0.28 0.6643 0.9244 2068897 IFLab1_006170 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cccnc2)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I11 compound treatment 0.332 0.00988 0.39 0.332 0.00819 0.17 0.3957 0.9324 2068898 IFLab1_006171 COc1ccccc1N(C(=O)C)S(=O)(=O)c2ccc(Cl)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I12 compound treatment 0.337 0.0149 0.58 0.347 0.0232 0.49 0.7567 0.9957 1537771 IFLab1_006172 COC(=O)c1c(NC(=O)COc2ccc(OC)cc2)sc3CCCCc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I13 compound treatment 0.355 0.0329 1.29 0.353 0.0292 0.61 1.3459 0.9414 2068899 IFLab1_006173 COc1ccc(cc1)n2nnnc2c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I14 compound treatment 0.341 0.0189 0.74 0.327 0.00319 0.07 0.5719 0.7676 2068900 IFLab1_006174 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(Cl)cc2)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I15 compound treatment 0.345 0.0229 0.9 0.31 -0.0138 -0.29 0.4316 0.4568 2068901 IFLab1_006175 Cc1nc2ccccc2n1CC3CC3(Cl)Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I16 compound treatment 0.334 0.0119 0.47 0.333 0.00919 0.19 0.4661 0.9231 2068902 IFLab1_006176 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(F)cc2)c3ccccn3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I17 compound treatment 0.345 0.0229 0.9 0.336 0.0122 0.26 0.8163 0.8732 2068903 IFLab1_006177 Cc1cc2ncn(Cc3ccccc3F)c2cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I18 compound treatment 0.33 0.00788 0.31 0.334 0.0102 0.21 0.3697 0.9834 2068904 IFLab1_006178 CC(C)NC(CC(=O)Nc1cccc(C)c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I19 compound treatment 0.339 0.0169 0.66 0.325 0.00119 0.02 0.4867 0.7331 2068905 IFLab1_006179 CCC(C)Cn1c(nc2ccccc12)C(C)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I20 compound treatment 0.327 0.00488 0.19 0.344 0.0202 0.42 0.4343 0.9361 2068906 IFLab1_006180 Cc1c(C)c2cc(C)ccc2n1CC(O)CN3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I21 compound treatment 0.322 -1.25E-4 0.0 0.331 0.00719 0.15 0.1029 0.6836 2068907 IFLab1_006181 CC(C)N1C(=O)/C(=C\2/C(=O)Nc3ccccc23)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I22 compound treatment 0.328 0.00588 0.23 0.307 -0.0168 -0.35 -0.0854 -0.203 2068908 IFLab1_006182 COC(=O)c1ccc(/C=[N+](\[O-])/c2ccccc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I23 mock treatment 0.301 -0.0211 -0.83 0.329 0.00519 0.11 -0.5106 -0.6095 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 I24 positive control 0.083 -0.239 -9.4 0.085 -0.239 -5.0 -10.1819 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J01 compound treatment 0.335 0.0129 0.51 0.338 0.0142 0.3 0.5679 0.9677 2068909 IFLab1_006183 Cc1ccc2cccc(c2n1)S(=O)(=O)N3CCCc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J02 compound treatment 0.359 0.0369 1.45 0.347 0.0232 0.49 1.3683 0.895 2068910 IFLab1_006184 COc1cc(/C=C\2/S/C(=N/c3cccc(Cl)c3Cl)/NC2=O)cc(OC)c1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J03 compound treatment 0.317 -0.00512 -0.2 0.301 -0.0228 -0.48 -0.48 -0.9264 1155277 IFLab1_006185 NC(=O)CCn1c(=O)oc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J04 compound treatment 0.442 0.12 4.71 0.425 0.101 2.12 4.83 0.9348 2068911 IFLab1_006186 CCOc1cc(/C=C\2/SC(=S)N(C(C(=O)O)c3ccccc3)C2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J05 compound treatment 0.321 -0.00112 -0.04 0.324 1.88E-4 0.0 -0.0285 -0.6419 2068912 IFLab1_006187 CCC(=O)Nc1ccc(cc1)S(=O)(=O)NC(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J06 compound treatment 0.338 0.0159 0.62 0.352 0.0282 0.59 0.8585 0.9996 2068913 IFLab1_006188 Oc1ccccc1/C=N/c2c(c3ccccc3)c4cc(Br)ccc4[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J07 compound treatment 0.342 0.0199 0.78 0.35 0.0262 0.55 0.9401 0.9849 2068914 IFLab1_006189 COC(=O)CNC(c1ccccc1)c2cc(Cl)ccc2NC(=O)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J08 compound treatment 0.36 0.0379 1.49 0.356 0.0322 0.67 1.5293 0.9357 1428158 IFLab1_006190 CN(C)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J09 compound treatment 0.35 0.0279 1.1 0.346 0.0222 0.46 1.1033 0.9269 1785243 IFLab1_006191 Brc1ccc2[nH]c(=O)c(CN3CCOCC3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J10 compound treatment 0.331 0.00888 0.35 0.324 1.88E-4 0.0 0.2495 0.715 1072842 IFLab1_006192 COc1ccc(OCCC(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J11 compound treatment 0.336 0.0139 0.55 0.329 0.00519 0.11 0.4625 0.8315 2068915 IFLab1_006193 O=C(N1CCOCC1)c2cc3ccccc3c(=O)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J12 compound treatment 0.328 0.00588 0.23 0.321 -0.00281 -0.06 0.1217 0.5106 2068916 IFLab1_006194 Cc1ccc(cc1)c2nnco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J13 compound treatment 0.34 0.0179 0.7 0.342 0.0182 0.38 0.7661 0.9585 2068917 IFLab1_006195 CCc1cccc(C)c1N(C(C)COC)C(=O)Cn2c(COC)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J14 compound treatment 0.335 0.0129 0.51 0.325 0.00119 0.02 0.3755 0.7409 1877847 IFLab1_006196 OC(=O)c1ccc(CC2SC(=O)NC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J15 compound treatment 0.333 0.0109 0.43 0.326 0.00219 0.05 0.3347 0.7784 2068918 IFLab1_006197 CCn1c(nc2ccccc12)c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J16 compound treatment 0.367 0.0449 1.76 0.35 0.0262 0.55 1.6351 0.885 1594185 IFLab1_006198 Clc1ccc(Cl)c(c1)c2ccc(o2)C(=O)Nc3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J17 compound treatment 0.346 0.0239 0.94 0.322 -0.00181 -0.04 0.637 0.678 2068919 IFLab1_006199 CN(Cc1ccccc1)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J18 compound treatment 0.342 0.0199 0.78 0.341 0.0172 0.36 0.8069 0.938 2068920 IFLab1_006200 Cc1ccccc1N/2C(=O)C(Cc3ccccc3)S\C2=C(\C#N)/C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J19 compound treatment 0.342 0.0199 0.78 0.358 0.0342 0.72 1.0584 0.999 2068921 IFLab1_006201 CC1(C)C(OCC(O)CN2CCN(CC2)c3cccc(c3)C(F)(F)F)C4(C)CCC1C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J20 compound treatment 0.325 0.00288 0.11 0.347 0.0232 0.49 0.423 0.8491 2068922 IFLab1_006202 CCCNS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J21 compound treatment 0.334 0.0119 0.47 0.329 0.00519 0.11 0.4069 0.8489 2068923 IFLab1_006203 Cc1cc(C)nc(SCc2csc(n2)c3ccccc3)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J22 compound treatment 0.335 0.0129 0.51 0.338 0.0142 0.3 0.5679 0.9677 2068924 IFLab1_006204 Cc1ccc(N2C(=O)CC(Nc3ccc(cc3)N4CCOCC4)C2=O)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J23 mock treatment 0.319 -0.00312 -0.12 0.324 1.88E-4 0.0 -0.0841 -0.6842 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 J24 positive control 0.084 -0.238 -9.36 0.086 -0.238 -4.98 -10.1393 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K01 compound treatment 0.348 0.0259 1.02 0.348 0.0242 0.51 1.0773 0.9481 1150198 IFLab1_006205 O=C(Nc1nccs1)c2cccc3C(=O)c4ccccc4-c32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K02 compound treatment 0.315 -0.00712 -0.28 0.317 -0.00681 -0.14 -0.2989 -0.9509 2068925 IFLab1_006206 CC(C)n1c(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K03 compound treatment 0.329 0.00688 0.27 0.33 0.00619 0.13 0.2827 0.9432 2068926 IFLab1_006207 O=C(/N=C/1\SC2CS(=O)(=O)CC2N1c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K04 compound treatment 0.318 -0.00412 -0.16 0.319 -0.00481 -0.1 -0.1859 -0.9737 2068927 IFLab1_006208 O=c1oc2ccccc2n1CCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K05 compound treatment 0.316 -0.00612 -0.24 0.32 -0.00381 -0.08 -0.2267 -0.8936 2068928 IFLab1_006209 CNc1nnc(CSc2nc(C)cc(C)n2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K06 compound treatment 0.323 8.75E-4 0.03 0.341 0.0172 0.36 0.2787 0.7712 2068929 IFLab1_006210 Cc1ccc(s1)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K07 compound treatment 0.327 0.00488 0.19 0.337 0.0132 0.28 0.3307 0.9841 2068930 IFLab1_006211 COc1ccc(cc1OC)C(=O)n2c(SC)nc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K08 compound treatment 0.336 0.0139 0.55 0.337 0.0132 0.28 0.5809 0.9502 2068931 IFLab1_006212 Cc1nc2ccccc2cc1C(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K09 compound treatment 0.387 0.0649 2.55 0.375 0.0512 1.07 2.5611 0.9257 2068932 IFLab1_006213 COc1ccc(cc1)c2nc3scc(c4ccccc4)n3n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K10 compound treatment 0.369 0.0469 1.84 0.362 0.0382 0.8 1.8683 0.93 2068933 IFLab1_006214 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)/C=C/c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K11 compound treatment 0.333 0.0109 0.43 0.321 -0.00281 -0.06 0.2607 0.6041 2068934 IFLab1_006215 CC1CCCCN1S(=O)(=O)c2cc(Cl)ccc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K12 compound treatment 0.332 0.00988 0.39 0.335 0.0112 0.23 0.4401 0.9707 2068935 IFLab1_006216 O=C(NCCC1=CCCCC1)/C=C/c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K13 compound treatment 0.337 0.0149 0.58 0.329 0.00519 0.11 0.4903 0.8243 2068936 IFLab1_006217 Cc1cccc(c1)n2nnnc2c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K14 compound treatment 0.335 0.0129 0.51 0.323 -8.12E-4 -0.02 0.3459 0.683 1289756 IFLab1_006218 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K15 compound treatment 0.349 0.0269 1.06 0.329 0.00519 0.11 0.8239 0.7757 2068937 IFLab1_006219 CCCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K16 compound treatment 0.113 -0.209 -8.22 0.109 -0.215 -4.5 -8.9927 -0.9596 2068938 IFLab1_006220 Cc1ccc(cc1)c2nc(N)s[n+]2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K17 compound treatment 0.338 0.0159 0.62 0.335 0.0112 0.23 0.6069 0.9104 2068939 IFLab1_006221 Cc1cc2ncn(C(=O)c3ccccc3C(=O)O)c2cc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K18 compound treatment 0.336 0.0139 0.55 0.341 0.0172 0.36 0.6401 0.9796 2068940 IFLab1_006222 CC(C)NC(CC(=O)Nc1ccccc1Cl)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K19 compound treatment 0.368 0.0459 1.8 0.371 0.0472 0.99 1.9737 0.9598 2068941 IFLab1_006223 CCN1C(=O)/C(=C\c2ccc(OCC(=O)N)c(OC)c2)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K20 compound treatment 0.333 0.0109 0.43 0.341 0.0172 0.36 0.5567 0.9963 2068942 IFLab1_006224 Cc1c(C)c2cc(C)ccc2n1CC(O)Cn3nnc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K21 compound treatment 0.344 0.0219 0.86 0.326 0.00219 0.05 0.6405 0.7437 2068943 IFLab1_006225 COc1cc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)ccc1OCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K22 compound treatment 0.34 0.0179 0.7 0.337 0.0132 0.28 0.6921 0.9166 2068944 IFLab1_006226 CCOC(=O)CSc1nc2ccccc2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K23 mock treatment 0.324 0.00188 0.07 0.321 -0.00281 -0.06 0.0105 0.1114 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 K24 positive control 0.085 -0.237 -9.32 0.09 -0.234 -4.89 -10.0523 -0.9547 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L01 compound treatment 0.334 0.0119 0.47 0.334 0.0102 0.21 0.4809 0.9369 2068945 IFLab1_006227 CSc1nnc(COc2cccc3ccc(C)nc23)n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L02 compound treatment 0.378 0.0559 2.2 0.385 0.0612 1.28 2.4588 0.967 2068946 IFLab1_006228 Clc1cccc(NC2=NC(=O)/C(=C\c3cccs3)/S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L03 compound treatment 0.332 0.00988 0.39 0.318 -0.00581 -0.12 0.1885 0.4634 2068947 IFLab1_006229 Cc1ccc2oc(=O)n(c2c1)S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L04 compound treatment 0.383 0.0609 2.39 0.382 0.0582 1.22 2.5535 0.9509 2068948 IFLab1_006230 COc1cc(/C=C\2/S/C(=N/c3ccccc3C(F)(F)F)/NC2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L05 compound treatment 0.322 -1.25E-4 0.0 0.335 0.0112 0.23 0.1621 0.6921 2068949 IFLab1_006231 Cc1ccccc1OCC(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L06 compound treatment 0.333 0.0109 0.43 0.337 0.0132 0.28 0.4975 0.9776 2068950 IFLab1_006232 OC(=O)Cn1c2ccc(Cl)cc2c3nc4ccccc4nc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L07 compound treatment 0.335 0.0129 0.51 0.327 0.00319 0.07 0.4051 0.7934 1142586 IFLab1_006233 COC(=O)Cc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L08 compound treatment 0.327 0.00488 0.19 0.321 -0.00281 -0.06 0.0939 0.4684 1550348 IFLab1_006234 CCN1CCN(CC1)C(=O)c2cc(nc3ccccc23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L09 compound treatment 0.326 0.00388 0.15 0.321 -0.00281 -0.06 0.0661 0.4048 1785242 IFLab1_006235 Cc1ccc2[nH]c(=O)c(CN3CCCCC3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L10 compound treatment 0.319 -0.00312 -0.12 0.331 0.00719 0.15 0.0195 0.1003 2068951 IFLab1_006236 Cc1cccc(OCCC(=O)O)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L11 compound treatment 0.336 0.0139 0.55 0.33 0.00619 0.13 0.4773 0.8513 2068952 IFLab1_006237 CC(=C)Cn1c(nc2ccccc12)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L12 compound treatment 0.343 0.0209 0.82 0.337 0.0132 0.28 0.7755 0.8956 1052523 IFLab1_006238 Oc1ccccc1c2nnco2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L13 compound treatment 0.339 0.0169 0.66 0.333 0.00919 0.19 0.6051 0.876 2068953 IFLab1_006239 CCn1c(nc2ccccc12)c3cccc(C)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L14 compound treatment 0.166 -0.156 -6.14 0.203 -0.121 -2.53 -6.1283 -0.9231 2068954 IFLab1_006240 Cc1ccc(cc1C)C2=CC(=O)C=CC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L15 compound treatment 0.343 0.0209 0.82 0.325 0.00119 0.02 0.5979 0.7282 1871622 IFLab1_006241 COc1ccccc1Nc2nc3ccccc3[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L16 compound treatment 0.342 0.0199 0.78 0.342 0.0182 0.38 0.8217 0.9453 2068955 IFLab1_006242 NS(=O)(=O)c1ccc(NC(=O)c2ccc(o2)c3ccccc3Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L17 compound treatment 0.373 0.0509 2.0 0.35 0.0262 0.55 1.8019 0.8688 2068956 IFLab1_006243 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)NCc4ccccn4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L18 compound treatment 0.343 0.0209 0.82 0.348 0.0242 0.51 0.9383 0.973 2068957 IFLab1_006244 CC1S/C(=C(/C#N)\C(=O)N)/N(C1=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L19 compound treatment 0.329 0.00688 0.27 0.326 0.00219 0.05 0.2235 0.8152 2068958 IFLab1_006245 CC1CC(CC(C)(C)C1)OCC(O)CN2CCN(Cc3ccc(Cl)cc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L20 compound treatment 0.336 0.0139 0.55 0.338 0.0142 0.3 0.5957 0.9591 2068959 IFLab1_006246 CC(C)NS(=O)(=O)c1ccc(NC(=O)c2ccncc2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L21 compound treatment 0.344 0.0219 0.86 0.325 0.00119 0.02 0.6257 0.7272 2068960 IFLab1_006247 Brc1ccc(cc1)C(=O)CS[n+]2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L22 compound treatment 0.336 0.0139 0.55 0.325 0.00119 0.02 0.4033 0.7386 2068961 IFLab1_006248 O=C(CC1Nc2ccccc2NC1=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L23 mock treatment 0.327 0.00488 0.19 0.328 0.00419 0.09 0.1975 0.9371 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 L24 positive control 0.086 -0.236 -9.28 0.088 -0.236 -4.93 -10.0541 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M01 compound treatment 0.329 0.00688 0.27 0.326 0.00219 0.05 0.2235 0.8152 2068962 IFLab1_006249 Cc1nc2ccccc2n1CC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M02 compound treatment 0.327 0.00488 0.19 0.332 0.00819 0.17 0.2567 0.9984 2068963 IFLab1_006250 Fc1ccc(Cn2c(nc3ccccc23)c4ccco4)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M03 compound treatment 0.309 -0.0131 -0.52 0.317 -0.00681 -0.14 -0.4657 -0.8699 1670110 IFLab1_006251 CC(=O)N(C1CS(=O)(=O)C=C1)c2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M04 compound treatment 0.331 0.00888 0.35 0.319 -0.00481 -0.1 0.1755 0.4833 2068964 IFLab1_006252 CC(C)N(C(=O)Cn1c(=O)oc2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M05 compound treatment 0.381 0.0589 2.31 0.397 0.0732 1.53 2.7198 0.9799 2068965 IFLab1_006253 COc1ccc(NC(=O)CCCSc2nc3sc(C)c(C)c3c(=O)[nH]2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M06 compound treatment 0.297 -0.0251 -0.99 0.297 -0.0268 -0.56 -1.0953 -0.9641 2068966 IFLab1_006254 Cc1ccc(s1)S(=O)(=O)N2CCCC(C2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M07 compound treatment 0.323 8.75E-4 0.03 0.321 -0.00281 -0.06 -0.0173 -0.2536 2068967 IFLab1_006255 CSc1nc2ccccc2n1C(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M08 compound treatment 0.358 0.0359 1.41 0.34 0.0162 0.34 1.2369 0.8527 2068968 IFLab1_006256 Cc1nc2ccccc2cc1C(=O)Nc3cccc(F)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M09 compound treatment 0.345 0.0229 0.9 0.336 0.0122 0.26 0.8163 0.8732 2068969 IFLab1_006257 CN(C)C(=O)c1cn(nc1c2cc3ccccc3oc2=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M10 compound treatment 0.332 0.00988 0.39 0.339 0.0152 0.32 0.4993 0.9951 2068970 IFLab1_006258 C[n+]1noc(NC(=O)C(F)(F)F)c1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M11 compound treatment 0.343 0.0209 0.82 0.34 0.0162 0.34 0.8199 0.9234 2068971 IFLab1_006259 Brc1ccc(NP2(=O)CC=CC2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M12 compound treatment 0.341 0.0189 0.74 0.34 0.0162 0.34 0.7643 0.9369 2068972 IFLab1_006260 Cc1cc(C)n(n1)C(=O)COc2cc(C)cc(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M13 compound treatment 0.326 0.00388 0.15 0.328 0.00419 0.09 0.1697 0.9655 2068973 IFLab1_006261 COc1ccccc1n2nnnc2c3ccc4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M14 compound treatment 0.369 0.0469 1.84 0.365 0.0412 0.86 1.9127 0.9401 1312516 IFLab1_006262 CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M15 compound treatment 0.341 0.0189 0.74 0.344 0.0202 0.42 0.8235 0.9643 2068974 IFLab1_006263 CCC(=O)NCCc1nc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M16 compound treatment 0.363 0.0409 1.61 0.362 0.0382 0.8 1.7015 0.948 2068975 IFLab1_006264 Cc1ccc(cc1)c2nc(Nc3ccccc3)n[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M17 compound treatment 0.348 0.0259 1.02 0.334 0.0102 0.21 0.8701 0.8371 1142502 IFLab1_006265 Cc1ccccc1OCCn2cnc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M18 compound treatment 0.344 0.0219 0.86 0.332 0.00819 0.17 0.7293 0.8316 2068976 IFLab1_006266 COc1ccc(NC(=O)CC(NC(C)c2ccccc2)C(=O)O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M19 compound treatment 0.284 -0.0381 -1.5 0.302 -0.0218 -0.46 -1.3827 -0.8824 2068977 IFLab1_006267 CCN(CC)c1ccc(/C=C\2/SC(=S)N(CC)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M20 compound treatment 0.33 0.00788 0.31 0.337 0.0132 0.28 0.4141 0.9984 2068978 IFLab1_006268 Cc1cc(C)n(CC(O)Cn2c(C)c(C)c3cc(C)ccc23)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M21 compound treatment 0.352 0.0299 1.17 0.314 -0.00981 -0.21 0.6854 0.5748 2068979 IFLab1_006269 O=S(=O)(/N=C(\Nc1ccccn1)/c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M22 compound treatment 0.306 -0.0161 -0.63 0.331 0.00719 0.15 -0.342 -0.5248 2068980 IFLab1_006270 OCCNC(=O)CSc1nc2ccccc2c(=O)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M23 mock treatment 0.328 0.00588 0.23 0.331 0.00719 0.15 0.2697 0.9784 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 M24 positive control 0.088 -0.234 -9.21 0.091 -0.233 -4.87 -9.9541 -0.9557 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N01 compound treatment 0.325 0.00288 0.11 0.33 0.00619 0.13 0.1715 0.9977 1398650 IFLab1_006271 Cc1cc(Nc2ccccc2)n(n1)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N02 compound treatment 0.361 0.0389 1.53 0.372 0.0482 1.01 1.7938 0.9796 2068981 IFLab1_006272 Brc1ccccc1NC2=NC(=O)/C(=C\c3cccs3)/S2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N03 compound treatment 0.314 -0.00812 -0.32 0.314 -0.00981 -0.21 -0.3711 -0.9772 2068982 IFLab1_006273 NC(=O)CCn1c(=O)sc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N04 compound treatment 0.362 0.0399 1.57 0.36 0.0362 0.76 1.6441 0.9443 2068983 IFLab1_006274 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3C(F)(F)F)/NC2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N05 compound treatment 0.3 -0.0221 -0.87 0.32 -0.00381 -0.08 -0.6715 -0.7687 1753888 IFLab1_006275 CN1CCN(CC1)S(=O)(=O)c2ccc(N)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N06 compound treatment 0.328 0.00588 0.23 0.329 0.00519 0.11 0.2401 0.9407 2068984 IFLab1_006276 Cc1ccc2oc(=O)n(CCOc3ccccc3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N07 compound treatment 0.325 0.00288 0.11 0.328 0.00419 0.09 0.1419 0.9921 1580625 IFLab1_006277 CCOC(=O)Cc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N08 compound treatment 0.334 0.0119 0.47 0.329 0.00519 0.11 0.4069 0.8489 2068985 IFLab1_006278 O=C/1/C(=C/c2cccnc2)/CCCC\C1=C/c3cccnc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N09 compound treatment 0.404 0.0819 3.22 0.399 0.0752 1.57 3.3888 0.9458 1219786 IFLab1_006279 Clc1ccc2[nH]c(=O)c(NS(=O)(=O)c3ccccc3)c(c4ccccc4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N10 compound treatment 0.322 -1.25E-4 0.0 0.323 -8.12E-4 -0.02 -0.0155 -0.8757 1321283 IFLab1_006280 OC(=O)Cn1c(Cc2ccccc2)nc3ccccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N11 compound treatment 0.329 0.00688 0.27 0.343 0.0192 0.4 0.4751 0.9815 2068986 IFLab1_006281 CC(O)c1nc2ccccc2n1Cc3ccccc3F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N12 compound treatment 0.343 0.0209 0.82 0.342 0.0182 0.38 0.8495 0.939 2068987 IFLab1_006282 C(Sc1nnc(o1)c2ccccc2)c3cn4ccccc4n3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N13 compound treatment 0.329 0.00688 0.27 0.33 0.00619 0.13 0.2827 0.9432 2068988 IFLab1_006283 CCC(=O)NCc1nc2ccccc2n1Cc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N14 compound treatment 0.352 0.0299 1.17 0.347 0.0232 0.49 1.1737 0.9235 2068989 IFLab1_006284 Cc1ccc(cc1C)c2cc(O)cc3sc(=O)oc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N15 compound treatment 0.298 -0.0241 -0.95 0.323 -8.12E-4 -0.02 -0.6827 -0.7197 2068990 IFLab1_006285 COc1ccccc1Nc2nc3ccccc3n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N16 compound treatment 0.324 0.00188 0.07 0.326 0.00219 0.05 0.0845 0.9737 2068991 IFLab1_006286 COC(=O)c1ccccc1NC(=O)c2ccc(o2)c3ccccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N17 compound treatment 0.344 0.0219 0.86 0.359 0.0352 0.74 1.1288 0.997 2068992 IFLab1_006287 CN(CCc1ccccn1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N18 compound treatment 0.329 0.00688 0.27 0.327 0.00319 0.07 0.2383 0.8559 2068993 IFLab1_006288 CC1=CS/C(=C(/C#N)\C(=O)NCc2ccco2)/N1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N19 compound treatment 0.342 0.0199 0.78 0.321 -0.00281 -0.06 0.5109 0.652 2068994 IFLab1_006289 OC(COc1ccccc1)CN2CCN(Cc3ccc(Cl)cc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N20 compound treatment 0.346 0.0239 0.94 0.344 0.0202 0.42 0.9625 0.935 2068995 IFLab1_006290 CC(C)NS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N21 compound treatment 0.337 0.0149 0.58 0.349 0.0252 0.53 0.7863 0.9987 2068996 IFLab1_006291 O=C(ON1C(=O)c2cccc3cccc(C1=O)c23)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N22 compound treatment 0.335 0.0129 0.51 0.329 0.00519 0.11 0.4347 0.8397 2068997 IFLab1_006292 CCc1cc(C(=O)OC)c(NC(=O)CC2Sc3ccccc3NC2=O)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N23 mock treatment 0.327 0.00488 0.19 0.33 0.00619 0.13 0.2271 0.9818 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 N24 positive control 0.089 -0.233 -9.17 0.091 -0.233 -4.87 -9.9263 -0.9563 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O01 compound treatment 0.322 -1.25E-4 0.0 0.318 -0.00581 -0.12 -0.0895 -0.7351 1128682 IFLab1_006293 CC(C)(C)NC(=O)C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O02 compound treatment 0.312 -0.0101 -0.4 0.315 -0.00881 -0.18 -0.4119 -0.9388 2068998 IFLab1_006294 CCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O03 compound treatment 0.308 -0.0141 -0.56 0.307 -0.0168 -0.35 -0.6415 -0.9757 1195801 IFLab1_006295 COc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O04 compound treatment 0.307 -0.0151 -0.59 0.315 -0.00881 -0.18 -0.5509 -0.8848 2068999 IFLab1_006296 COC(=O)Cn1c(=O)oc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O05 compound treatment 0.364 0.0419 1.65 0.356 0.0322 0.67 1.6405 0.9222 2069000 IFLab1_006297 COc1ccc(cc1)c2csc(n2)C(=C(SC)SC)C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O06 compound treatment 0.322 -1.25E-4 0.0 0.322 -0.00181 -0.04 -0.0303 -0.7921 2069001 IFLab1_006298 Cc1ccc(s1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O07 compound treatment 0.327 0.00488 0.19 0.324 1.88E-4 0.0 0.1383 0.7214 2069002 IFLab1_006299 Fc1ccc2c(Cl)c(sc2c1)C(=O)Nc3ccc(cc3)N4CCOCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O08 compound treatment 0.326 0.00388 0.15 0.323 -8.12E-4 -0.02 0.0957 0.6243 2069003 IFLab1_006300 CN(C)N/C(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O09 compound treatment 0.324 0.00188 0.07 0.329 0.00519 0.11 0.1289 0.9822 2069004 IFLab1_006301 O=C(N1CCCCC1)c2cn(nc2c3ccncc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O10 compound treatment 0.325 0.00288 0.11 0.327 0.00319 0.07 0.1271 0.9683 1019444 IFLab1_006302 C[n+]1noc(O)c1c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O11 compound treatment 0.328 0.00588 0.23 0.321 -0.00281 -0.06 0.1217 0.5106 2069005 IFLab1_006303 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O12 compound treatment 0.339 0.0169 0.66 0.351 0.0272 0.57 0.8715 0.9971 2069006 IFLab1_006304 Cc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CC(C)(C)CC3=O)N2)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O13 compound treatment 0.355 0.0329 1.29 0.351 0.0272 0.57 1.3163 0.9321 2069007 IFLab1_006305 COc1ccc(cc1)n2nnnc2c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O14 compound treatment 0.365 0.0429 1.69 0.338 0.0142 0.3 1.4019 0.819 2069008 IFLab1_006306 COc1ccc(cc1Cl)C(=O)C2=C(O)C(=O)N(CCN(C)C)C2c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O15 compound treatment 0.332 0.00988 0.39 0.337 0.0132 0.28 0.4697 0.986 2069009 IFLab1_006307 CC(C)C(=O)NCCCc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O16 compound treatment 0.803 0.481 18.91 0.777 0.453 9.48 20.0752 0.9491 2069010 IFLab1_006308 O/N=C\1/C=C(CN2CCCCC2)C(=O)c3ncccc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O17 compound treatment 0.327 0.00488 0.19 0.339 0.0152 0.32 0.3603 0.9707 2069011 IFLab1_006309 COCc1nc2ccccc2n1CCOc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O18 compound treatment 0.343 0.0209 0.82 0.339 0.0152 0.32 0.8051 0.9147 2069012 IFLab1_006310 CN(C)C(CC(=O)Nc1cccc(c1)C(F)(F)F)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O19 compound treatment 0.349 0.0269 1.06 0.343 0.0192 0.4 1.0311 0.9122 2069013 IFLab1_006311 CCN1C(=O)/C(=C/2\C(=O)Nc3ccccc23)/SC1=S 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O20 compound treatment 0.338 0.0159 0.62 0.343 0.0192 0.4 0.7253 0.9772 2069014 IFLab1_006312 COc1ccc(cc1)N/2C(=O)CS\C2=N\S(=O)(=O)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O21 compound treatment 0.342 0.0199 0.78 0.343 0.0192 0.4 0.8365 0.9521 2069015 IFLab1_006313 FC(F)(F)c1nc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O22 compound treatment 0.34 0.0179 0.7 0.339 0.0152 0.32 0.7217 0.9356 2069016 IFLab1_006314 Cc1sc2c(c1C)c(=O)nc3scc(CC(=O)NCCO)n32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O23 mock treatment 0.323 8.75E-4 0.03 0.328 0.00419 0.09 0.0863 0.9166 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 O24 positive control 0.091 -0.231 -9.09 0.095 -0.229 -4.79 -9.8115 -0.9552 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P01 compound treatment 0.337 0.0149 0.58 0.34 0.0162 0.34 0.6531 0.9663 2069017 IFLab1_006315 Cc1c(cnn1c2ccccc2)C(=O)Nc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P02 compound treatment 0.348 0.0259 1.02 0.353 0.0292 0.61 1.1513 0.9702 2069018 IFLab1_006316 FC(F)(F)c1cccc(NC2=NC(=O)/C(=C\c3cccs3)/S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P03 compound treatment 0.395 0.0729 2.87 0.412 0.0882 1.85 3.331 0.9774 2069019 IFLab1_006317 NS(=O)(=O)c1ccc(Nc2nc3sc4CCCCc4c3c(=O)s2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P04 compound treatment 0.4 0.0779 3.06 0.401 0.0772 1.62 3.3072 0.9553 2069020 IFLab1_006318 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3F)/NC2=O)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P05 compound treatment 0.366 0.0439 1.73 0.35 0.0262 0.55 1.6073 0.888 2069021 IFLab1_006319 Fc1ccc(cc1)c2cnnn2c3ccc(cc3)C(=O)COC(=O)c4ccccc4F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P06 compound treatment 0.365 0.0429 1.69 0.362 0.0382 0.8 1.7571 0.9418 2069022 IFLab1_006320 COc1ccccc1Cn2c(=O)oc3ccc(C)cc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P07 compound treatment 0.394 0.0719 2.83 0.372 0.0482 1.01 2.7113 0.9036 1785239 IFLab1_006321 OC(=O)Cc1c(c2ccccc2)c3cc(Br)ccc3[nH]c1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P08 compound treatment 0.371 0.0489 1.92 0.363 0.0392 0.82 1.9387 0.9279 2069023 IFLab1_006322 OC(=O)c1ccc(OC(F)(F)F)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P09 compound treatment 0.412 0.0899 3.53 0.415 0.0912 1.91 3.848 0.9582 1327154 IFLab1_006323 Cc1ccc(cc1)S(=O)(=O)Nc2c(c3ccccc3)c4cc(C)ccc4[nH]c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P10 compound treatment 0.375 0.0529 2.08 0.366 0.0422 0.88 2.0943 0.9272 1134203 IFLab1_006324 CCOC(=O)CC(=O)Nc1nc2ccccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P11 compound treatment 0.364 0.0419 1.65 0.357 0.0332 0.69 1.6553 0.9263 2069024 IFLab1_006325 CCC(C)Cn1c(CO)nc2ccccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P12 compound treatment 0.377 0.0549 2.16 0.358 0.0342 0.72 2.0315 0.8937 2069025 IFLab1_006326 Cc1ccnc(SCc2nc3ccc(Cl)cn3c2Br)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P13 compound treatment 0.377 0.0549 2.16 0.353 0.0292 0.61 1.9575 0.873 2069026 IFLab1_006327 CC(=O)NCCc1nc2ccccc2n1Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P14 compound treatment 0.399 0.0769 3.02 0.423 0.0992 2.08 3.605 0.9832 2069027 IFLab1_006328 CCOc1ccc(cc1)c2cc(O)cc3sc(=O)oc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P15 compound treatment 0.358 0.0359 1.41 0.344 0.0202 0.42 1.2961 0.8803 2069028 IFLab1_006329 CN(C)CCNc1nc2ccccc2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P16 compound treatment 0.361 0.0389 1.53 0.363 0.0392 0.82 1.6607 0.9574 2069029 IFLab1_006330 Clc1cccc(c1)c2ccc(o2)C(=O)NCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P17 compound treatment 0.347 0.0249 0.98 0.349 0.0252 0.53 1.0643 0.9579 2069030 IFLab1_006331 Cc1cc(ccc1F)S(=O)(=O)N2CCOCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P18 compound treatment 0.351 0.0289 1.14 0.348 0.0242 0.51 1.1607 0.9338 2069031 IFLab1_006332 CC1=CS/C(=C(/C#N)\C(=O)N2CCOCC2)/N1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P19 compound treatment 0.352 0.0299 1.17 0.349 0.0252 0.53 1.2033 0.9346 2069032 IFLab1_006333 Cc1cc(C)nc(SCC(=O)CSc2nc(C)cc(C)n2)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P20 compound treatment 0.379 0.0569 2.24 0.366 0.0422 0.88 2.2055 0.9174 2069033 IFLab1_006334 CC(NC(=O)CC1Sc2ccccc2NC1=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P21 compound treatment 0.341 0.0189 0.74 0.338 0.0142 0.3 0.7347 0.9192 2069034 IFLab1_006335 OC(=O)CNS(=O)(=O)c1ccc(Cl)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P22 compound treatment 0.34 0.0179 0.7 0.349 0.0252 0.53 0.8697 0.9899 2069035 IFLab1_006336 CC(C)N1C(=O)CC(Nc2ccc(cc2)N3CCOCC3)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P23 mock treatment 0.34 0.0179 0.7 0.328 0.00419 0.09 0.5589 0.7892 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1429 P24 positive control 0.094 -0.228 -8.97 0.1 -0.224 -4.68 -9.6541 -0.9541 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A01 compound treatment 0.342 0.00792 0.31 0.343 -0.072 -1.51 -0.845 -0.5494 2069036 IFLab1_006337 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A02 compound treatment 0.326 -0.00808 -0.32 0.317 -0.098 -2.05 -1.6746 -0.8071 1986286 IFLab1_006338 COCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4cccc(O)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A03 compound treatment 0.317 -0.0171 -0.67 0.319 -0.096 -2.01 -1.8952 -0.8949 2069037 IFLab1_006339 Cc1cccc(c1C)n2c(SCC(=O)O)nnc2c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A04 compound treatment 0.32 -0.0141 -0.55 0.338 -0.077 -1.61 -1.5307 -0.8986 2069038 IFLab1_006340 COCCN1C(c2c(oc3ccc(F)cc3c2=O)C1=O)c4cccc(OCC=C)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A05 compound treatment 0.346 0.0119 0.47 0.318 -0.097 -2.03 -1.1038 -0.5299 2069039 IFLab1_006341 O=S(=O)(N1CCCC1)c2cccc(c2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A06 compound treatment 0.323 -0.0111 -0.44 0.317 -0.098 -2.05 -1.758 -0.8387 2069040 IFLab1_006342 Cc1c(oc2ccc(C)cc12)C(=O)N(Cc3ccccc3)C4CCS(=O)(=O)C4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A07 compound treatment 0.322 -0.0121 -0.48 0.349 -0.066 -1.38 -1.3123 -0.8987 2069041 IFLab1_006343 CC(C)c1ccc(cc1)S(=O)(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A08 compound treatment 0.35 0.0159 0.63 0.324 -0.091 -1.9 -0.9038 -0.451 2069042 IFLab1_006344 CC1SC(C)C(=O)N(CC(=O)Nc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A09 compound treatment 0.89 0.556 21.86 0.918 0.503 10.53 22.8988 0.9439 2069043 IFLab1_006345 Oc1ccc2cc(c(=O)oc2c1)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A10 compound treatment 0.322 -0.0121 -0.48 0.337 -0.078 -1.63 -1.4899 -0.8766 2069044 IFLab1_006346 CCC1SC(CC)C(=O)N(CC(=O)NCCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A11 compound treatment 0.351 0.0169 0.67 0.329 -0.086 -1.8 -0.802 -0.4181 1346298 IFLab1_006347 Cn1c(=NC(=O)c2ccc(cc2)N3C(=O)CCC3=O)sc4ccccc14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A12 compound treatment 0.327 -0.00708 -0.28 0.343 -0.072 -1.51 -1.2621 -0.8239 2069045 IFLab1_006348 CC1SCC(=O)N(CC(=O)Nc2ccccc2C(F)(F)F)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A13 compound treatment 0.322 -0.0121 -0.48 0.326 -0.089 -1.86 -1.6526 -0.86 2069046 IFLab1_006349 Cn1c(SCc2nc3ccccc3s2)nnc1c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A14 compound treatment 0.339 0.00492 0.19 0.334 -0.081 -1.69 -1.0616 -0.6224 2069047 IFLab1_006350 CCSC1=NCCN1S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A15 compound treatment 0.324 -0.0101 -0.4 0.329 -0.086 -1.8 -1.5526 -0.8427 2069048 IFLab1_006351 CCCOc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)O)n2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A16 compound treatment 0.319 -0.0151 -0.59 0.317 -0.098 -2.05 -1.8692 -0.8757 2069049 IFLab1_006352 CCS(=O)(=O)N1CCN=C1SC(C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A17 compound treatment 0.345 0.0109 0.43 0.312 -0.103 -2.15 -1.2204 -0.5554 2069050 IFLab1_006353 CC(Oc1ccccc1F)C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A18 compound treatment 0.325 -0.00908 -0.36 0.327 -0.088 -1.84 -1.5544 -0.8288 2069051 IFLab1_006354 CS(=O)(=O)N1CCN=C1SCc2ccc(cc2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A19 compound treatment 0.317 -0.0171 -0.67 0.326 -0.089 -1.86 -1.7916 -0.9051 2069052 IFLab1_006355 Cc1cc(C)cc(OCC(=O)N2CCN(Cc3ccccc3)CC2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A20 compound treatment 0.339 0.00492 0.19 0.345 -0.07 -1.46 -0.8989 -0.6085 2069053 IFLab1_006356 CC1CC(C)CN(C1)C(c2sc3ncnn3c2O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A21 compound treatment 0.348 0.0139 0.55 0.333 -0.082 -1.72 -0.8262 -0.4588 2069054 IFLab1_006357 CCOc1cccc(c1)C2N(Cc3ccccc3)C(=O)C(=C2C(=O)c4ccc(C)o4)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A22 compound treatment 0.319 -0.0151 -0.59 0.317 -0.098 -2.05 -1.8692 -0.8757 2069055 IFLab1_006358 CC(C)Sc1nnc(CSc2ncccn2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A23 mock treatment 0.312 -0.0221 -0.87 0.315 -0.1 -2.09 -2.0934 -0.9241 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 A24 positive control 0.079 -0.255 -10.03 0.079 -0.336 -7.03 -12.0634 -0.9849 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B01 compound treatment 0.339 0.00492 0.19 0.338 -0.077 -1.61 -1.0024 -0.6179 2069056 IFLab1_006359 COc1cccc2c(=O)n(CC(=O)N3CCc4ccccc34)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B02 mock treatment 0.324 -0.0101 -0.4 0.377 -0.038 -0.79 -0.8424 -0.9484 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B03 compound treatment 0.324 -0.0101 -0.4 0.412 -0.00298 -0.06 -0.3245 -0.8084 2069057 IFLab1_006360 Cn1cccc1Cc2nnc(SCC(=O)NC3CCCC3)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B04 mock treatment 0.323 -0.0111 -0.44 0.424 0.00902 0.19 -0.1747 -0.3679 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B05 compound treatment 0.325 -0.00908 -0.36 0.474 0.059 1.24 0.6207 0.4828 2069058 IFLab1_006361 NNc1nc2c3CCCCc3ccc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B06 mock treatment 0.32 -0.0141 -0.55 0.454 0.039 0.82 0.1858 0.1883 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B07 compound treatment 0.327 -0.00708 -0.28 0.439 0.024 0.5 0.1584 0.2757 1060996 IFLab1_006362 COc1ccc2nc(Cl)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B08 mock treatment 0.326 -0.00808 -0.32 0.451 0.036 0.75 0.3082 0.3768 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B09 mock treatment 0.328 -0.00608 -0.24 0.446 0.031 0.65 0.2898 0.4189 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B10 mock treatment 0.326 -0.00808 -0.32 0.452 0.037 0.77 0.323 0.3857 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B11 mock treatment 0.33 -0.00408 -0.16 0.458 0.043 0.9 0.523 0.5719 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B12 mock treatment 0.323 -0.0111 -0.44 0.435 0.02 0.42 -0.012 -0.0198 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B13 mock treatment 0.331 -0.00308 -0.12 0.43 0.015 0.31 0.1365 0.4051 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B14 mock treatment 0.324 -0.0101 -0.4 0.44 0.025 0.52 0.0898 0.1368 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B15 mock treatment 0.328 -0.00608 -0.24 0.411 -0.00398 -0.08 -0.2281 -0.9003 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B16 mock treatment 0.336 0.00192 0.08 0.409 -0.00598 -0.13 -0.0353 -0.2414 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B17 mock treatment 0.329 -0.00508 -0.2 0.408 -0.00698 -0.15 -0.2447 -0.9881 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B18 mock treatment 0.339 0.00492 0.19 0.41 -0.00498 -0.1 0.063 0.2867 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B19 mock treatment 0.328 -0.00608 -0.24 0.422 0.00702 0.15 -0.0653 -0.2326 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B20 mock treatment 0.332 -0.00208 -0.08 0.436 0.021 0.44 0.2531 0.5656 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B21 compound treatment 0.336 0.00192 0.08 0.422 0.00702 0.15 0.1571 0.9518 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B22 mock treatment 0.329 -0.00508 -0.2 0.42 0.00502 0.11 -0.0671 -0.2971 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B23 mock treatment 0.322 -0.0121 -0.48 0.385 -0.03 -0.63 -0.7796 -0.9906 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 B24 positive control 0.078 -0.256 -10.07 0.08 -0.335 -7.01 -12.0764 -0.9843 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C01 compound treatment 0.146 -0.188 -7.4 0.184 -0.231 -4.83 -8.647 -0.9788 2069059 IFLab1_006363 CCc1cc(C(=O)OC)c(s1)N2C(=O)C=CC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C02 compound treatment 0.324 -0.0101 -0.4 0.425 0.01 0.21 -0.1321 -0.2946 2069060 IFLab1_006364 COCCN1C(c2c(oc3cc(C)c(C)cc3c2=O)C1=O)c4ccccc4F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C03 compound treatment 0.327 -0.00708 -0.28 0.427 0.012 0.25 -0.0191 -0.0509 2069061 IFLab1_006365 CSc1nnc(c2cccs2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C04 compound treatment 0.33 -0.00408 -0.16 0.452 0.037 0.77 0.4342 0.5488 2069062 IFLab1_006366 COCCN1C(c2c(oc3ccc(F)cc3c2=O)C1=O)c4ccc(OCC=C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C05 compound treatment 0.332 -0.00208 -0.08 0.519 0.104 2.18 1.4812 0.68 1558055 IFLab1_006367 CC(=O)N1CC(=O)Nc2ccc(F)cc2C1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C06 compound treatment 0.342 0.00792 0.31 0.528 0.113 2.37 1.8924 0.7933 2069063 IFLab1_006368 COC(=O)c1ccc2O/C(=C/c3ccccc3O)/C(=O)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C07 compound treatment 0.333 -0.00108 -0.04 0.473 0.058 1.21 0.8284 0.6818 2069064 IFLab1_006369 O=C(NC1CCCCC1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C08 compound treatment 0.334 -8.5E-5 0.0 0.465 0.05 1.05 0.7378 0.7048 2069065 IFLab1_006370 CC1SC(C)C(=O)N(CC(=O)NC2CCCCC2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C09 compound treatment 0.338 0.00392 0.15 0.468 0.053 1.11 0.8934 0.7976 2069066 IFLab1_006371 Cc1ccc(CCNC(=O)CC(C)(C)CC2=Nc3ccccc3S(=O)(=O)N2)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C10 compound treatment 0.341 0.00692 0.27 0.455 0.04 0.84 0.7844 0.8909 2069067 IFLab1_006372 CC1SCC(=O)N(CC(=O)Nc2cccc(C)c2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C11 compound treatment 0.336 0.00192 0.08 0.469 0.054 1.13 0.8526 0.7525 1627112 IFLab1_006373 CCOc1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCCC3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C12 compound treatment 0.324 -0.0101 -0.4 0.466 0.051 1.07 0.4746 0.4167 2069068 IFLab1_006374 CC1SCC(=O)N(CC(=O)NCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C13 compound treatment 0.333 -0.00108 -0.04 0.444 0.029 0.61 0.3992 0.6558 2069069 IFLab1_006375 OC(=O)CSc1nnc(c2cccs2)n1c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C14 compound treatment 0.332 -0.00208 -0.08 0.443 0.028 0.59 0.3566 0.6024 2069070 IFLab1_006376 CCSC1=NCCN1S(=O)(=O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C15 compound treatment 0.348 0.0139 0.55 0.446 0.031 0.65 0.8459 0.9964 2069071 IFLab1_006377 O=S(=O)(/C(=C\C1=Cc2ccccc2OC1)/C#N)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C16 compound treatment 0.319 -0.0151 -0.59 0.434 0.019 0.4 -0.138 -0.1931 2069072 IFLab1_006378 CC(SC1=NCCN1S(=O)(=O)c2ccccc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C17 compound treatment 0.338 0.00392 0.15 0.456 0.041 0.86 0.7158 0.8208 2069073 IFLab1_006379 COC(=O)c1nc(oc1Nc2ccc(C)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C18 compound treatment 0.332 -0.00208 -0.08 0.455 0.04 0.84 0.5342 0.6349 2069074 IFLab1_006380 CCS(=O)(=O)N1CCN=C1SCc2ccc(cc2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C19 compound treatment 0.337 0.00292 0.11 0.468 0.053 1.11 0.8656 0.776 2069075 IFLab1_006381 COCCN1C(C(=C(O)C1=O)C(=O)c2ccc3OC(C)Cc3c2)c4ccc(Cl)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C20 compound treatment 0.335 9.15E-4 0.04 0.43 0.015 0.31 0.2477 0.7829 2069076 IFLab1_006382 CC1CN(CC(C)O1)C(c2sc3ncnn3c2O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C21 compound treatment 0.344 0.00992 0.39 0.446 0.031 0.65 0.7347 0.9702 2069077 IFLab1_006383 COC(=O)Nc1sc(nc1c2cccs2)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C22 compound treatment 0.331 -0.00308 -0.12 0.412 -0.00298 -0.06 -0.1299 -0.9522 2069078 IFLab1_006384 CSc1nnc(CSc2ncccn2)n1c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C23 mock treatment 0.318 -0.0161 -0.63 0.383 -0.032 -0.67 -0.9204 -0.9996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 C24 positive control 0.078 -0.256 -10.07 0.081 -0.334 -6.99 -12.0616 -0.9841 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D01 compound treatment 0.34 0.00592 0.23 0.331 -0.084 -1.76 -1.0782 -0.6082 2069079 IFLab1_006385 COc1cccc2c(=O)n(CC(=O)N)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D02 mock treatment 0.315 -0.0191 -0.75 0.432 0.017 0.36 -0.2788 -0.3356 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D03 compound treatment 0.32 -0.0141 -0.55 0.443 0.028 0.59 0.023 0.0285 2069080 IFLab1_006386 Cn1cccc1Cc2nnc(SCC(=O)NCc3ccccc3)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D04 mock treatment 0.325 -0.00908 -0.36 0.46 0.045 0.94 0.4136 0.4105 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D05 compound treatment 0.328 -0.00608 -0.24 0.48 0.065 1.36 0.7929 0.574 2069081 IFLab1_006387 Cc1cccc2sc(NN)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D06 mock treatment 0.333 -0.00108 -0.04 0.475 0.06 1.26 0.858 0.6827 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D07 compound treatment 0.327 -0.00708 -0.28 0.465 0.05 1.05 0.5432 0.5015 1688617 IFLab1_006388 COc1cccc2sc(N)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D08 mock treatment 0.335 9.15E-4 0.04 0.482 0.067 1.4 1.0171 0.725 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D09 mock treatment 0.34 0.00592 0.23 0.461 0.046 0.96 0.8454 0.8533 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D10 mock treatment 0.343 0.00892 0.35 0.455 0.04 0.84 0.84 0.9253 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D11 mock treatment 0.341 0.00692 0.27 0.469 0.054 1.13 0.9916 0.8529 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D12 mock treatment 0.332 -0.00208 -0.08 0.464 0.049 1.03 0.6674 0.6485 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D13 mock treatment 0.332 -0.00208 -0.08 0.466 0.051 1.07 0.697 0.6509 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D14 mock treatment 0.335 9.15E-4 0.04 0.457 0.042 0.88 0.6472 0.7354 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D15 mock treatment 0.331 -0.00308 -0.12 0.425 0.01 0.21 0.0625 0.258 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D16 mock treatment 0.33 -0.00408 -0.16 0.412 -0.00298 -0.06 -0.1577 -0.9151 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D17 mock treatment 0.333 -0.00108 -0.04 0.415 1.96E-5 0.0 -0.0299 -0.7003 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D18 mock treatment 0.331 -0.00308 -0.12 0.436 0.021 0.44 0.2253 0.4937 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D19 mock treatment 0.335 9.15E-4 0.04 0.467 0.052 1.09 0.7952 0.7301 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D20 mock treatment 0.332 -0.00208 -0.08 0.471 0.056 1.17 0.771 0.6561 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D21 compound treatment 0.333 -0.00108 -0.04 0.46 0.045 0.94 0.636 0.6744 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D22 mock treatment 0.329 -0.00508 -0.2 0.444 0.029 0.61 0.288 0.4505 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D23 mock treatment 0.323 -0.0111 -0.44 0.386 -0.029 -0.61 -0.737 -0.9869 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 D24 positive control 0.079 -0.255 -10.03 0.084 -0.331 -6.93 -11.9894 -0.9837 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E01 compound treatment 0.198 -0.136 -5.35 0.183 -0.232 -4.85 -7.2161 -0.9988 2069082 IFLab1_006389 COC(=O)c1c(sc2CC(CCc12)C(C)(C)C)N3C(=O)C=CC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E02 compound treatment 0.336 0.00192 0.08 0.422 0.00702 0.15 0.1571 0.9518 2069083 IFLab1_006390 COCCN1C(c2c(oc3ccc(Br)cc3c2=O)C1=O)c4ccc(Cl)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E03 compound treatment 0.338 0.00392 0.15 0.466 0.051 1.07 0.8638 0.8008 2069084 IFLab1_006391 Cc1ccc2cccc(c2n1)S(=O)(=O)Nc3ccc4OCOc4c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E04 compound treatment 0.341 0.00692 0.27 0.461 0.046 0.96 0.8732 0.8726 2069085 IFLab1_006392 COc1ccc(cc1F)C(=O)C2=C(O)C(=O)N(CCCO)C2c3cccc(Br)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E05 compound treatment 0.332 -0.00208 -0.08 0.463 0.048 1.0 0.6526 0.6473 2069086 IFLab1_006393 Cc1ccc2NC(=O)CN=C(c3ccc(F)cc3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E06 compound treatment 0.352 0.0179 0.7 0.484 0.069 1.44 1.5194 0.9455 2069087 IFLab1_006394 Fc1ccccc1C(=O)Nc2c(oc3ccccc23)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E07 compound treatment 0.34 0.00592 0.23 0.474 0.059 1.24 1.0378 0.8257 2069088 IFLab1_006395 Fc1cccc(Cn2c(=O)c3ccccc3n4nncc24)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E08 compound treatment 0.355 0.0209 0.82 0.48 0.065 1.36 1.5436 0.9709 2069089 IFLab1_006396 CC1SC(C)C(=O)N(CC(=O)NCc2ccco2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E09 compound treatment 0.345 0.0109 0.43 0.456 0.041 0.86 0.9104 0.9487 2069090 IFLab1_006397 Cc1ccc(C)c(NC2=NC3CS(=O)(=O)CC3S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E10 compound treatment 0.34 0.00592 0.23 0.479 0.064 1.34 1.1118 0.8176 2069091 IFLab1_006398 CC1SCC(=O)N(CC(=O)Nc2ccc(C)cc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E11 compound treatment 0.336 0.00192 0.08 0.488 0.073 1.53 1.1337 0.7411 1700163 IFLab1_006399 CCOc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E12 compound treatment 0.332 -0.00208 -0.08 0.488 0.073 1.53 1.0225 0.6682 2069092 IFLab1_006400 CC1SCC(=O)N(CC(=O)NCCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E13 compound treatment 0.339 0.00492 0.19 0.485 0.07 1.47 1.1727 0.7935 2069093 IFLab1_006401 Cc1ccc(cc1S(=O)(=O)N2CCCC2)c3nc4ccccc4s3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E14 compound treatment 0.328 -0.00608 -0.24 0.46 0.045 0.94 0.497 0.5113 2069094 IFLab1_006402 CCSC1=NCCN1S(=O)(=O)c2ccc(NC(=O)C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E15 compound treatment 0.35 0.0159 0.63 0.449 0.034 0.71 0.9459 0.9979 2069095 IFLab1_006403 CC1Oc2ccccc2C=C1/C=C(\C#N)/c3nc(=O)c4ccccc4[nH]3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E16 compound treatment 0.333 -0.00108 -0.04 0.422 0.00702 0.15 0.0737 0.4819 2069096 IFLab1_006404 CC(SC1=NCCN1S(=O)(=O)c2ccc(NC(=O)C)cc2)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E17 compound treatment 0.332 -0.00208 -0.08 0.428 0.013 0.27 0.1347 0.4734 2069097 IFLab1_006405 O=C(Nc1c(nc2ncccn12)c3cccs3)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E18 compound treatment 0.335 9.15E-4 0.04 0.456 0.041 0.86 0.6324 0.7361 2069098 IFLab1_006406 CS(=O)(=O)N1CCN=C1SCc2ccc(Cl)c(Cl)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E19 compound treatment 0.337 0.00292 0.11 0.463 0.048 1.0 0.7916 0.7827 2069099 IFLab1_006407 Clc1ccc(CN(C2CCS(=O)(=O)C2)C(=O)c3ccc(Cl)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E20 compound treatment 0.333 -0.00108 -0.04 0.462 0.047 0.98 0.6656 0.6758 2069100 IFLab1_006408 CCN1CCN(CC1)C(c2sc3ncnn3c2O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E21 compound treatment 0.337 0.00292 0.11 0.461 0.046 0.96 0.762 0.7857 2069101 IFLab1_006409 Clc1ccc(OCC(=O)N(Cc2cccs2)C3CCS(=O)(=O)C3)c(Cl)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E22 compound treatment 0.316 -0.0181 -0.71 0.427 0.012 0.25 -0.3249 -0.4308 2069102 IFLab1_006410 CCSc1nnc(CSc2ncccn2)n1c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E23 mock treatment 0.317 -0.0171 -0.67 0.372 -0.043 -0.9 -1.111 -0.9897 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 E24 positive control 0.081 -0.253 -9.95 0.086 -0.329 -6.88 -11.9042 -0.9838 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F01 compound treatment 0.396 0.0619 2.43 0.393 -0.022 -0.46 1.3961 0.5635 2069103 IFLab1_006411 COc1cccc2c(=O)n(CC(=O)Nc3ccccc3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F02 mock treatment 0.305 -0.0291 -1.14 0.411 -0.00398 -0.08 -0.8675 -0.7566 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F03 compound treatment 0.336 0.00192 0.08 0.43 0.015 0.31 0.2755 0.8524 2069104 IFLab1_006412 Cc1ccc(NC(=O)c2cccn(OCc3ccc(F)cc3)c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F04 mock treatment 0.318 -0.0161 -0.63 0.425 0.01 0.21 -0.2989 -0.4487 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F05 compound treatment 0.341 0.00692 0.27 0.467 0.052 1.09 0.962 0.8574 2069105 IFLab1_006413 CCc1cccc2sc(NN)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F06 mock treatment 0.324 -0.0101 -0.4 0.448 0.033 0.69 0.2082 0.2614 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F07 compound treatment 0.329 -0.00508 -0.2 0.462 0.047 0.98 0.5544 0.5521 1430771 IFLab1_006414 CCOc1cccc2sc(N)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F08 mock treatment 0.338 0.00392 0.15 0.439 0.024 0.5 0.4643 0.8832 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F09 mock treatment 0.35 0.0159 0.63 0.461 0.046 0.96 1.1234 0.9782 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F10 mock treatment 0.338 0.00392 0.15 0.466 0.051 1.07 0.8638 0.8008 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F11 mock treatment 0.343 0.00892 0.35 0.461 0.046 0.96 0.9288 0.9063 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F12 mock treatment 0.334 -8.5E-5 0.0 0.45 0.035 0.73 0.5158 0.7039 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F13 mock treatment 0.342 0.00792 0.31 0.462 0.047 0.98 0.9158 0.8874 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F14 mock treatment 0.341 0.00692 0.27 0.467 0.052 1.09 0.962 0.8574 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F15 mock treatment 0.342 0.00792 0.31 0.44 0.025 0.52 0.5903 0.9691 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F16 mock treatment 0.348 0.0139 0.55 0.426 0.011 0.23 0.5499 0.9262 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F17 mock treatment 0.34 0.00592 0.23 0.427 0.012 0.25 0.3423 0.9992 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F18 mock treatment 0.346 0.0119 0.47 0.472 0.057 1.19 1.175 0.9166 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F19 mock treatment 0.334 -8.5E-5 0.0 0.468 0.053 1.11 0.7822 0.705 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F20 mock treatment 0.334 -8.5E-5 0.0 0.474 0.059 1.24 0.871 0.7052 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F21 compound treatment 0.336 0.00192 0.08 0.448 0.033 0.69 0.5418 0.7795 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F22 mock treatment 0.335 9.15E-4 0.04 0.439 0.024 0.5 0.3809 0.7558 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F23 mock treatment 0.322 -0.0121 -0.48 0.364 -0.051 -1.07 -1.0903 -0.9336 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 F24 positive control 0.081 -0.253 -9.95 0.084 -0.331 -6.93 -11.9338 -0.9843 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G01 compound treatment 0.137 -0.197 -7.75 0.159 -0.256 -5.36 -9.2671 -0.9837 2069106 IFLab1_006415 CCOC(=O)c1c(sc2CC(C)CCc12)N3C(=O)C=CC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G02 compound treatment 0.359 0.0249 0.98 0.431 0.016 0.34 0.9297 0.898 2069107 IFLab1_006416 CCOc1cccc(c1)C2N(CCCN(C)C)C(=O)c3oc4cc(C)c(C)cc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G03 compound treatment 0.311 -0.0231 -0.91 0.398 -0.017 -0.36 -0.8931 -0.9162 2069108 IFLab1_006417 CSc1nnc(COc2cccc3ccc(C)nc23)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G04 compound treatment 0.331 -0.00308 -0.12 0.414 -9.8E-4 -0.02 -0.1003 -0.8151 2069109 IFLab1_006418 COC(=O)c1ccc2O/C(=C\c3ccccc3F)/C(=O)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G05 compound treatment 0.337 0.00292 0.11 0.426 0.011 0.23 0.2441 0.9479 2069110 IFLab1_006419 Cc1nc(N)sc1c2nnc(Nc3ccccc3)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G06 compound treatment 0.329 -0.00508 -0.2 0.446 0.031 0.65 0.3176 0.4676 2069111 IFLab1_006420 CC(C)c1nnc(NC(=O)c2oc3ccc(C)cc3c2C)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G07 compound treatment 0.324 -0.0101 -0.4 0.446 0.031 0.65 0.1786 0.2348 2069112 IFLab1_006421 Fc1cccc(Cn2cc(C(=O)c3ccccc3)c(=O)c4cc(F)ccc24)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G08 compound treatment 0.322 -0.0121 -0.48 0.464 0.049 1.03 0.3894 0.3444 2069113 IFLab1_006422 CC1SC(C)C(=O)N(CC(=O)NCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G09 compound treatment 0.332 -0.00208 -0.08 0.462 0.047 0.98 0.6378 0.646 2069114 IFLab1_006423 CSc1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G10 compound treatment 0.334 -8.5E-5 0.0 0.472 0.057 1.19 0.8414 0.7051 2069115 IFLab1_006424 CCCCc1ccc(NC(=O)CN2C(=O)CSC(C)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G11 compound treatment 0.334 -8.5E-5 0.0 0.459 0.044 0.92 0.649 0.7045 1788580 IFLab1_006425 CCOc1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G12 compound treatment 0.34 0.00592 0.23 0.467 0.052 1.09 0.9342 0.8392 2069116 IFLab1_006426 CSC1=NCCN1S(=O)(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G13 compound treatment 0.346 0.0119 0.47 0.492 0.077 1.61 1.4709 0.8764 2069117 IFLab1_006427 Fc1cccc(c1)C2CC(=O)n3c(S2)nc4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G14 compound treatment 0.325 -0.00908 -0.36 0.472 0.057 1.19 0.5911 0.4746 2069118 IFLab1_006428 CCCS(=O)(=O)N1CCN=C1SCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G15 compound treatment 0.34 0.00592 0.23 0.487 0.072 1.51 1.2301 0.8067 2069119 IFLab1_006429 Clc1cccc(C=c2sc3nc(nn3c2=O)c4cccs4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G16 compound treatment 0.333 -0.00108 -0.04 0.482 0.067 1.4 0.9615 0.6853 2069120 IFLab1_006430 CCS(=O)(=O)N1CCN=C1SCc2ccccc2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G17 compound treatment 0.345 0.0109 0.43 0.492 0.077 1.61 1.4431 0.8652 1537635 IFLab1_006431 CCCOc1ccc(cc1)C(=O)Nc2ccc(cc2)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G18 compound treatment 0.331 -0.00308 -0.12 0.479 0.064 1.34 0.8615 0.6405 2069121 IFLab1_006432 CS(=O)(=O)N1CCN=C1SCc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G19 compound treatment 0.333 -0.00108 -0.04 0.456 0.041 0.86 0.5768 0.6711 2069122 IFLab1_006433 CC(Oc1ccc(F)cc1)C(=O)N(Cc2ccccc2Cl)C3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G20 compound treatment 0.33 -0.00408 -0.16 0.453 0.038 0.8 0.449 0.5532 2069123 IFLab1_006434 Oc1c(sc2ncnn12)C(N3CCOCC3)c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G21 compound treatment 0.329 -0.00508 -0.2 0.427 0.012 0.25 0.0365 0.1135 2069124 IFLab1_006435 COc1ccccc1C(=O)N(Cc2cccs2)C3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G22 compound treatment 0.322 -0.0121 -0.48 0.407 -0.00798 -0.17 -0.4541 -0.9016 2069125 IFLab1_006436 CCOc1ccc(cc1)n2c(CSc3nc(C)cc(C)n3)nnc2SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G23 mock treatment 0.316 -0.0181 -0.71 0.361 -0.054 -1.13 -1.3016 -0.9751 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 G24 positive control 0.081 -0.253 -9.95 0.098 -0.317 -6.63 -11.7267 -0.9806 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H01 compound treatment 0.332 -0.00208 -0.08 0.338 -0.077 -1.61 -1.1971 -0.7421 2069126 IFLab1_006437 COc1cccc2c(=O)n(CC(=O)NC3CCCC3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H02 mock treatment 0.316 -0.0181 -0.71 0.372 -0.043 -0.9 -1.1388 -0.9932 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H03 compound treatment 0.336 0.00192 0.08 0.478 0.063 1.32 0.9857 0.7463 2069127 IFLab1_006438 COc1ccc(NC(=O)c2cccn(OCc3ccc(F)cc3)c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H04 mock treatment 0.319 -0.0151 -0.59 0.421 0.00602 0.13 -0.3303 -0.5448 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H05 compound treatment 0.318 -0.0161 -0.63 0.423 0.00802 0.17 -0.3285 -0.5021 2069128 IFLab1_006439 COc1cccc2sc(NN)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H06 mock treatment 0.321 -0.0131 -0.51 0.433 0.018 0.38 -0.0972 -0.1523 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H07 compound treatment 0.341 0.00692 0.27 0.448 0.033 0.69 0.6808 0.9169 2069129 IFLab1_006440 NC(C(=O)O)C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H08 mock treatment 0.333 -0.00108 -0.04 0.454 0.039 0.82 0.5472 0.6693 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H09 mock treatment 0.334 -8.5E-5 0.0 0.455 0.04 0.84 0.5898 0.7043 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H10 mock treatment 0.349 0.0149 0.59 0.465 0.05 1.05 1.1548 0.9625 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H11 mock treatment 0.33 -0.00408 -0.16 0.459 0.044 0.92 0.5378 0.5751 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H12 mock treatment 0.336 0.00192 0.08 0.463 0.048 1.0 0.7638 0.758 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H13 mock treatment 0.333 -0.00108 -0.04 0.459 0.044 0.92 0.6212 0.6736 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H14 mock treatment 0.337 0.00292 0.11 0.466 0.051 1.07 0.836 0.7785 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H15 mock treatment 0.332 -0.00208 -0.08 0.464 0.049 1.03 0.6674 0.6485 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H16 mock treatment 0.331 -0.00308 -0.12 0.462 0.047 0.98 0.61 0.6153 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H17 mock treatment 0.337 0.00292 0.11 0.453 0.038 0.8 0.6436 0.8007 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H18 mock treatment 0.338 0.00392 0.15 0.453 0.038 0.8 0.6714 0.8285 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H19 mock treatment 0.336 0.00192 0.08 0.444 0.029 0.61 0.4826 0.7887 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H20 mock treatment 0.332 -0.00208 -0.08 0.443 0.028 0.59 0.3566 0.6024 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H21 compound treatment 0.333 -0.00108 -0.04 0.421 0.00602 0.13 0.0589 0.4429 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H22 mock treatment 0.33 -0.00408 -0.16 0.416 0.00102 0.02 -0.0985 -0.6078 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H23 mock treatment 0.321 -0.0131 -0.51 0.334 -0.081 -1.69 -1.5621 -0.882 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 H24 positive control 0.082 -0.252 -9.91 0.086 -0.329 -6.88 -11.8764 -0.9841 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I01 compound treatment 0.192 -0.142 -5.59 0.251 -0.164 -3.43 -6.3767 -0.9726 2069130 IFLab1_006441 CCOC(=O)c1cc(C)sc1N2C(=O)C=CC2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I02 compound treatment 0.335 9.15E-4 0.04 0.37 -0.045 -0.94 -0.6401 -0.6796 2069131 IFLab1_006442 OCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I03 compound treatment 0.339 0.00492 0.19 0.438 0.023 0.48 0.4773 0.9195 2069132 IFLab1_006443 Cn1c(SCc2nc3ccccc3s2)nnc1c4ccncc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I04 compound treatment 0.333 -0.00108 -0.04 0.432 0.017 0.36 0.2217 0.618 2069133 IFLab1_006444 COc1ccc(cc1)C2N(CCCO)C(=O)c3oc4ccccc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I05 compound treatment 0.348 0.0139 0.55 0.455 0.04 0.84 0.979 0.9787 2069134 IFLab1_006445 COc1ccc(cc1OC)C2=Nc3ccccc3S(=O)(=O)N2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I06 compound treatment 0.334 -8.5E-5 0.0 0.461 0.046 0.96 0.6786 0.7046 2069135 IFLab1_006446 CC(C)C(=O)Nc1c(oc2ccccc12)C(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I07 compound treatment 0.359 0.0249 0.98 0.459 0.044 0.92 1.3441 0.9995 1206686 IFLab1_006447 O=c1oc2ccccc2cc1S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I08 compound treatment 0.358 0.0239 0.94 0.443 0.028 0.59 1.0795 0.9742 2069136 IFLab1_006448 CC1SC(C)C(=O)N(CC(=O)NCCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I09 compound treatment 0.339 0.00492 0.19 0.455 0.04 0.84 0.7288 0.848 2069137 IFLab1_006449 Cc1cc(C)cc(NC2=NC3CS(=O)(=O)CC3S2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I10 compound treatment 0.35 0.0159 0.63 0.471 0.056 1.17 1.2714 0.9568 2069138 IFLab1_006450 CC1SCC(=O)N(CC(=O)Nc2ccc(F)cc2F)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I11 compound treatment 0.374 0.0399 1.57 0.533 0.118 2.47 2.8561 0.976 1218671 IFLab1_006451 CC1CCc2[nH]c(=NC(=O)c3ccc(F)c(F)c3)sc2C1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I12 compound treatment 0.333 -0.00108 -0.04 0.465 0.05 1.05 0.71 0.6777 2069139 IFLab1_006452 CSC1=NCCN1S(=O)(=O)c2ccc(Br)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I13 compound treatment 0.34 0.00592 0.23 0.48 0.065 1.36 1.1266 0.8161 2069140 IFLab1_006453 Cc1ccc(cc1S(=O)(=O)N2CCCC2)C(=O)N3CCN(CC3)c4ccccc4F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I14 compound treatment 0.337 0.00292 0.11 0.465 0.05 1.05 0.8212 0.7799 2069141 IFLab1_006454 CS(=O)(=O)N1CCN=C1SCc2cccc(F)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I15 compound treatment 0.41 0.0759 2.98 0.538 0.123 2.57 3.9309 0.9973 1657893 IFLab1_006455 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c4cccc(Cl)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I16 compound treatment 0.353 0.0189 0.74 0.484 0.069 1.44 1.5472 0.9524 2069142 IFLab1_006456 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN=C2SCc3c(F)cccc3Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I17 compound treatment 0.339 0.00492 0.19 0.502 0.087 1.82 1.4243 0.7778 2069143 IFLab1_006457 CCCOc1ccc(cc1C)c2cc(n[nH]2)C(=O)NO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I18 compound treatment 0.336 0.00192 0.08 0.441 0.026 0.54 0.4383 0.7973 2069144 IFLab1_006458 CCS(=O)(=O)N1CCN=C1SCc2cccc3ccccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I19 compound treatment 0.338 0.00392 0.15 0.445 0.03 0.63 0.553 0.8551 2069145 IFLab1_006459 Clc1ccc(CN(C2CCS(=O)(=O)C2)C(=O)c3cc4ccccc4oc3=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I20 compound treatment 0.335 9.15E-4 0.04 0.426 0.011 0.23 0.1885 0.8077 2069146 IFLab1_006460 CCSc1nnc(CSc2ncccn2)n1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I21 compound treatment 0.333 -0.00108 -0.04 0.412 -0.00298 -0.06 -0.0743 -0.9828 2069147 IFLab1_006461 COCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4ccc(C)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I22 compound treatment 0.332 -0.00208 -0.08 0.391 -0.024 -0.5 -0.4128 -0.8119 2069148 IFLab1_006462 CSc1nnc(CSc2nc(C)cc(C)n2)n1c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I23 mock treatment 0.324 -0.0101 -0.4 0.338 -0.077 -1.61 -1.4195 -0.8556 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 I24 positive control 0.082 -0.252 -9.91 0.087 -0.328 -6.86 -11.8616 -0.9839 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J01 compound treatment 0.333 -0.00108 -0.04 0.343 -0.072 -1.51 -1.0953 -0.7268 2069149 IFLab1_006463 COc1cccc2c(=O)n(CC(=O)NCc3ccccc3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J02 mock treatment 0.312 -0.0221 -0.87 0.353 -0.062 -1.3 -1.5311 -0.981 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J03 compound treatment 0.327 -0.00708 -0.28 0.405 -0.00998 -0.21 -0.3447 -0.9899 2069150 IFLab1_006464 Fc1ccc(COn2cccc(C(=O)Nc3cc(Cl)ccc3Cl)c2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J04 mock treatment 0.323 -0.0111 -0.44 0.414 -9.8E-4 -0.02 -0.3227 -0.7396 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J05 compound treatment 0.342 0.00792 0.31 0.442 0.027 0.57 0.6199 0.9604 2069151 IFLab1_006465 CCOc1ccc2nc(NN)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J06 mock treatment 0.318 -0.0161 -0.63 0.438 0.023 0.48 -0.1066 -0.1341 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J07 compound treatment 0.329 -0.00508 -0.2 0.414 -9.8E-4 -0.02 -0.1559 -0.7756 1081539 IFLab1_006466 NCC1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J08 mock treatment 0.336 0.00192 0.08 0.43 0.015 0.31 0.2755 0.8524 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J09 mock treatment 0.336 0.00192 0.08 0.453 0.038 0.8 0.6158 0.7706 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J10 mock treatment 0.333 -0.00108 -0.04 0.446 0.031 0.65 0.4288 0.6592 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J11 mock treatment 0.342 0.00792 0.31 0.452 0.037 0.77 0.7678 0.9197 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J12 mock treatment 0.343 0.00892 0.35 0.444 0.029 0.61 0.6773 0.9659 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J13 mock treatment 0.343 0.00892 0.35 0.447 0.032 0.67 0.7217 0.9543 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J14 mock treatment 0.334 -8.5E-5 0.0 0.461 0.046 0.96 0.6786 0.7046 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J15 mock treatment 0.333 -0.00108 -0.04 0.455 0.04 0.84 0.562 0.6702 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J16 mock treatment 0.342 0.00792 0.31 0.436 0.021 0.44 0.5311 0.9856 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J17 mock treatment 0.341 0.00692 0.27 0.46 0.045 0.94 0.8584 0.8754 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J18 mock treatment 0.343 0.00892 0.35 0.453 0.038 0.8 0.8104 0.9322 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J19 mock treatment 0.34 0.00592 0.23 0.465 0.05 1.05 0.9046 0.8436 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J20 mock treatment 0.342 0.00792 0.31 0.425 0.01 0.21 0.3683 0.9815 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J21 compound treatment 0.34 0.00592 0.23 0.426 0.011 0.23 0.3275 1.0 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J22 mock treatment 0.339 0.00492 0.19 0.403 -0.012 -0.25 -0.0406 -0.1283 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J23 mock treatment 0.321 -0.0131 -0.51 0.342 -0.073 -1.53 -1.4437 -0.8958 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 J24 positive control 0.084 -0.25 -9.83 0.088 -0.327 -6.84 -11.7912 -0.9843 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K01 compound treatment 0.337 0.00292 0.11 0.346 -0.069 -1.44 -0.9397 -0.6489 2069152 IFLab1_006467 O=C(N1CCN(CC1)c2ccccc2)c3cccc(c3)S(=O)(=O)N4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K02 compound treatment 0.322 -0.0121 -0.48 0.344 -0.071 -1.49 -1.3863 -0.8889 2069153 IFLab1_006468 COc1cccc(c1)C2N(CCO)C(=O)c3oc4ccccc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K03 compound treatment 0.325 -0.00908 -0.36 0.369 -0.046 -0.96 -0.933 -0.909 2069154 IFLab1_006469 CSc1nnc(NC(=O)/C=C/c2cccc(F)c2)s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K04 compound treatment 0.318 -0.0161 -0.63 0.391 -0.024 -0.5 -0.802 -0.9934 2069155 IFLab1_006470 COc1ccc(cc1)C2N(CC=C)C(=O)c3oc4ccccc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K05 compound treatment 0.323 -0.0111 -0.44 0.418 0.00302 0.06 -0.2635 -0.5983 2069156 IFLab1_006471 COc1ccc(cc1OC)c2nnn(c2N)c3cccc(c3)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K06 compound treatment 0.326 -0.00808 -0.32 0.448 0.033 0.69 0.2638 0.3469 2069157 IFLab1_006472 O=C(CN1C(=O)CSCC1=O)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K07 compound treatment 0.322 -0.0121 -0.48 0.441 0.026 0.54 0.049 0.0678 2069158 IFLab1_006473 COc1ccc2cc(c(=O)oc2c1)S(=O)(=O)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K08 compound treatment 0.341 0.00692 0.27 0.436 0.021 0.44 0.5033 0.9733 2069159 IFLab1_006474 CCC1SC(CC)C(=O)N(CC(=O)Nc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K09 compound treatment 0.33 -0.00408 -0.16 0.449 0.034 0.71 0.3898 0.5342 2069160 IFLab1_006475 Clc1ccc(NC2=NC3CS(=O)(=O)CC3S2)cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K10 compound treatment 0.341 0.00692 0.27 0.453 0.038 0.8 0.7548 0.8978 2069161 IFLab1_006476 COc1ccccc1NC(=O)CN2C(=O)CSC(C)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K11 compound treatment 0.363 0.0289 1.14 0.512 0.097 2.03 2.2395 0.9624 2069162 IFLab1_006477 NS(=O)(=O)c1ccc2nc(NC(=O)c3cccs3)sc2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K12 compound treatment 0.332 -0.00208 -0.08 0.45 0.035 0.73 0.4602 0.6241 2069163 IFLab1_006478 COc1ccc(cc1)S(=O)(=O)N2CCN=C2SC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K13 compound treatment 0.338 0.00392 0.15 0.454 0.039 0.82 0.6862 0.8259 2069164 IFLab1_006479 COc1ccc(cc1OC)c2nnc(SCC(=O)c3ccccc3)n2CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K14 compound treatment 0.334 -8.5E-5 0.0 0.449 0.034 0.71 0.501 0.7038 2069165 IFLab1_006480 CCS(=O)(=O)N1CCN=C1SCc2cccc(F)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K15 compound treatment 0.334 -8.5E-5 0.0 0.472 0.057 1.19 0.8414 0.7051 2069166 IFLab1_006481 CCOc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K16 compound treatment 0.342 0.00792 0.31 0.465 0.05 1.05 0.9602 0.8793 2069167 IFLab1_006482 CCS(=O)(=O)N1CCN=C1SCc2cccc(C)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K17 compound treatment 0.355 0.0209 0.82 0.48 0.065 1.36 1.5436 0.9709 2069168 IFLab1_006483 CC(=O)Oc1cccc(C=c2sc3nc(nn3c2=O)c4ccc(F)cc4)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K18 compound treatment 0.334 -8.5E-5 0.0 0.455 0.04 0.84 0.5898 0.7043 2069169 IFLab1_006484 CS(=O)(=O)N1CCN=C1SCc2cccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K19 compound treatment 0.342 0.00792 0.31 0.451 0.036 0.75 0.753 0.9234 2069170 IFLab1_006485 CC1Cc2cc(ccc2O1)C(=O)C3=C(O)C(=O)N(CCN(C)C)C3c4cccs4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K20 compound treatment 0.342 0.00792 0.31 0.438 0.023 0.48 0.5607 0.9777 2069171 IFLab1_006486 CSc1nnc(CSc2ncccn2)n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K21 compound treatment 0.34 0.00592 0.23 0.434 0.019 0.4 0.4459 0.9673 2069172 IFLab1_006487 COc1ccc(cc1)C2N(CCCOC(C)C)C(=O)c3oc4ccccc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K22 compound treatment 0.338 0.00392 0.15 0.43 0.015 0.31 0.3311 0.946 2069173 IFLab1_006488 COc1cccc2c(=O)n(CC(=O)N3CCCC3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K23 mock treatment 0.319 -0.0151 -0.59 0.373 -0.042 -0.88 -1.0406 -0.9817 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 K24 positive control 0.085 -0.249 -9.79 0.09 -0.325 -6.8 -11.7338 -0.9841 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L01 compound treatment 0.334 -8.5E-5 0.0 0.346 -0.069 -1.44 -1.0231 -0.7087 2069174 IFLab1_006489 Cn1cccc1Cc2nnc(SCC(=O)N3CCCc4ccccc34)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L02 mock treatment 0.31 -0.0241 -0.95 0.327 -0.088 -1.84 -1.9715 -0.9522 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L03 compound treatment 0.329 -0.00508 -0.2 0.378 -0.037 -0.77 -0.6886 -0.8615 2069175 IFLab1_006490 Cc1[nH]c2ccccc2c1CCNCc3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L04 mock treatment 0.32 -0.0141 -0.55 0.39 -0.025 -0.52 -0.7612 -0.9996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L05 compound treatment 0.361 0.0269 1.06 0.446 0.031 0.65 1.2073 0.9725 2069176 IFLab1_006491 NNc1nc2c(Cl)cc(Cl)cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L06 mock treatment 0.328 -0.00608 -0.24 0.405 -0.00998 -0.21 -0.3169 -0.9977 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L07 compound treatment 0.329 -0.00508 -0.2 0.423 0.00802 0.17 -0.0227 -0.087 2069177 IFLab1_006492 NC(=O)c1oc2ccccc2c1NC(=O)c3cccs3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L08 mock treatment 0.333 -0.00108 -0.04 0.417 0.00202 0.04 -3.0E-4 -0.0047 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L09 mock treatment 0.327 -0.00708 -0.28 0.429 0.014 0.29 0.0105 0.0259 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L10 mock treatment 0.332 -0.00208 -0.08 0.43 0.015 0.31 0.1643 0.5058 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L11 mock treatment 0.336 0.00192 0.08 0.454 0.039 0.82 0.6306 0.769 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L12 mock treatment 0.331 -0.00308 -0.12 0.446 0.031 0.65 0.3732 0.5652 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L13 mock treatment 0.345 0.0109 0.43 0.445 0.03 0.63 0.7477 0.9827 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L14 mock treatment 0.34 0.00592 0.23 0.44 0.025 0.52 0.5347 0.9333 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L15 mock treatment 0.341 0.00692 0.27 0.451 0.036 0.75 0.7252 0.9051 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L16 mock treatment 0.331 -0.00308 -0.12 0.441 0.026 0.54 0.2992 0.5364 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L17 mock treatment 0.341 0.00692 0.27 0.449 0.034 0.71 0.6956 0.9129 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L18 mock treatment 0.333 -0.00108 -0.04 0.447 0.032 0.67 0.4436 0.6608 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L19 mock treatment 0.337 0.00292 0.11 0.447 0.032 0.67 0.5548 0.8162 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L20 mock treatment 0.335 9.15E-4 0.04 0.442 0.027 0.57 0.4253 0.7506 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L21 compound treatment 0.34 0.00592 0.23 0.429 0.014 0.29 0.3719 0.9934 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L22 mock treatment 0.331 -0.00308 -0.12 0.432 0.017 0.36 0.1661 0.4414 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L23 mock treatment 0.322 -0.0121 -0.48 0.396 -0.019 -0.4 -0.6168 -0.996 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 L24 positive control 0.086 -0.248 -9.75 0.091 -0.324 -6.78 -11.6912 -0.9842 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M01 compound treatment 0.326 -0.00808 -0.32 0.336 -0.079 -1.65 -1.3935 -0.8279 2069178 IFLab1_006493 Cc1ccc(cc1S(=O)(=O)NCc2ccco2)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M02 compound treatment 0.322 -0.0121 -0.48 0.319 -0.096 -2.01 -1.7562 -0.8509 2069179 IFLab1_006494 Brc1ccc(cc1)C(=O)N(Cc2ccco2)C3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M03 compound treatment 0.312 -0.0221 -0.87 0.354 -0.061 -1.28 -1.5163 -0.9824 2069180 IFLab1_006495 NC(=O)CSc1nnc(c2cccs2)n1CC=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M04 compound treatment 0.331 -0.00308 -0.12 0.38 -0.035 -0.73 -0.6034 -0.8132 2069181 IFLab1_006496 COc1cc(ccc1O)C2N(CC=C)C(=O)c3oc4ccccc4c(=O)c23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M05 compound treatment 0.332 -0.00208 -0.08 0.409 -0.00598 -0.13 -0.1465 -0.979 2069182 IFLab1_006497 Nc1c(nnn1c2ccccc2)c3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M06 compound treatment 0.32 -0.0141 -0.55 0.391 -0.024 -0.5 -0.7464 -0.9988 2069183 IFLab1_006498 Fc1ccc(CNC(=O)CN2C(=O)CSCC2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M07 compound treatment 0.34 0.00592 0.23 0.4 -0.015 -0.31 -0.0572 -0.1466 2069184 IFLab1_006499 Cc1ccc(cc1C)S(=O)(=O)c2cc3ccccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M08 compound treatment 0.327 -0.00708 -0.28 0.427 0.012 0.25 -0.0191 -0.0509 2069185 IFLab1_006500 CCC1SC(CC)C(=O)N(CC(=O)NC2CCCCC2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M09 compound treatment 0.366 0.0319 1.25 0.451 0.036 0.75 1.4203 0.9703 2069186 IFLab1_006501 O=C(NCc1ccccc1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M10 compound treatment 0.336 0.00192 0.08 0.423 0.00802 0.17 0.1719 0.9346 2069187 IFLab1_006502 CCOc1ccccc1NC(=O)CN2C(=O)CSC(C)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M11 compound treatment 0.34 0.00592 0.23 0.417 0.00202 0.04 0.1943 0.8221 2069188 IFLab1_006503 OC(COc1ccccc1Cl)CN2CCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M12 compound treatment 0.348 0.0139 0.55 0.414 -9.8E-4 -0.02 0.3724 0.6801 2069189 IFLab1_006504 CSC1=NCCN1S(=O)(=O)c2ccc(NC(=O)C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M13 compound treatment 0.345 0.0109 0.43 0.418 0.00302 0.06 0.3481 0.8026 2069190 IFLab1_006505 COc1ccc(cc1)n2c(SC)nnc2c3ccc(OC)c(OC)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M14 compound treatment 0.347 0.0129 0.51 0.424 0.00902 0.19 0.4925 0.9092 2069191 IFLab1_006506 Fc1ccc(CSC2=NCCN2S(=O)(=O)c3ccc(F)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M15 compound treatment 0.348 0.0139 0.55 0.473 0.058 1.21 1.2454 0.9352 2069192 IFLab1_006507 Cc1ccc(cc1)C(=O)Nc2sc(CC#N)nc2c3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M16 compound treatment 0.331 -0.00308 -0.12 0.423 0.00802 0.17 0.0329 0.1589 2069193 IFLab1_006508 CCS(=O)(=O)N1CCN=C1SCc2ccc(C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M17 compound treatment 0.342 0.00792 0.31 0.431 0.016 0.34 0.4571 0.9993 2069194 IFLab1_006509 CCc1ccc(cc1)C2N(CCOC)C(=O)C(=C2C(=O)c3ccc4OC(C)Cc4c3)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M18 compound treatment 0.33 -0.00408 -0.16 0.441 0.026 0.54 0.2714 0.4782 2069195 IFLab1_006510 CCS(=O)(=O)N1CCN=C1SCc2ccc(Cl)cc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M19 compound treatment 0.33 -0.00408 -0.16 0.42 0.00502 0.11 -0.0393 -0.2048 2069196 IFLab1_006511 O=c1c(=Cc2ccccc2)sc3nc(nn13)c4ccco4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M20 compound treatment 0.33 -0.00408 -0.16 0.409 -0.00598 -0.13 -0.2021 -0.9924 2069197 IFLab1_006512 CCSc1nnc(CSc2ncccn2)n1CCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M21 compound treatment 0.349 0.0149 0.59 0.439 0.024 0.5 0.7701 0.9971 2069198 IFLab1_006513 Cc1ccc(C)c(c1)C(=O)C2=C(O)C(=O)N(CCc3ccccc3)C2c4ccc(O)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M22 compound treatment 0.321 -0.0131 -0.51 0.398 -0.017 -0.36 -0.615 -0.9837 2069199 IFLab1_006514 COc1cccc2c(=O)n(CC(=O)N3CCCCC3)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M23 mock treatment 0.331 -0.00308 -0.12 0.348 -0.067 -1.4 -1.0769 -0.7654 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 M24 positive control 0.088 -0.246 -9.68 0.093 -0.322 -6.74 -11.606 -0.9844 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N01 compound treatment 0.322 -0.0121 -0.48 0.341 -0.074 -1.55 -1.4307 -0.8835 2069200 IFLab1_006515 Cn1cccc1Cc2nnc(SCC(=O)N)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N02 mock treatment 0.309 -0.0251 -0.99 0.322 -0.093 -1.95 -2.0733 -0.9504 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N03 compound treatment 0.314 -0.0201 -0.79 0.335 -0.08 -1.67 -1.7419 -0.9412 2069201 IFLab1_006516 Cc1[nH]c2ccccc2c1CCNCc3ccncc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N04 mock treatment 0.32 -0.0141 -0.55 0.359 -0.056 -1.17 -1.2199 -0.9415 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N05 compound treatment 0.32 -0.0141 -0.55 0.383 -0.032 -0.67 -0.8648 -0.9956 2069202 IFLab1_006517 NNc1nc2cc3OCOc3cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N06 mock treatment 0.326 -0.00808 -0.32 0.383 -0.032 -0.67 -0.698 -0.9421 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N07 compound treatment 0.332 -0.00208 -0.08 0.393 -0.022 -0.46 -0.3832 -0.8202 1273015 IFLab1_006518 OC(=O)Cc1sc(NCC=C)nc1c2cccs2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N08 mock treatment 0.336 0.00192 0.08 0.417 0.00202 0.04 0.0831 0.9627 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N09 mock treatment 0.339 0.00492 0.19 0.389 -0.026 -0.54 -0.2478 -0.4294 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N10 mock treatment 0.33 -0.00408 -0.16 0.4 -0.015 -0.31 -0.3352 -0.9517 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N11 mock treatment 0.34 0.00592 0.23 0.415 1.96E-5 0.0 0.1647 0.7084 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N12 mock treatment 0.342 0.00792 0.31 0.41 -0.00498 -0.1 0.1464 0.446 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N13 mock treatment 0.339 0.00492 0.19 0.399 -0.016 -0.33 -0.0998 -0.2584 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N14 mock treatment 0.341 0.00692 0.27 0.413 -0.00198 -0.04 0.1629 0.5925 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N15 mock treatment 0.333 -0.00108 -0.04 0.402 -0.013 -0.27 -0.2222 -0.8082 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N16 mock treatment 0.339 0.00492 0.19 0.399 -0.016 -0.33 -0.0998 -0.2584 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N17 mock treatment 0.335 9.15E-4 0.04 0.383 -0.032 -0.67 -0.4478 -0.6681 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N18 mock treatment 0.339 0.00492 0.19 0.379 -0.036 -0.75 -0.3958 -0.5091 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N19 mock treatment 0.336 0.00192 0.08 0.39 -0.025 -0.52 -0.3164 -0.5991 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N20 mock treatment 0.34 0.00592 0.23 0.385 -0.03 -0.63 -0.2792 -0.4172 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N21 compound treatment 0.34 0.00592 0.23 0.373 -0.042 -0.88 -0.4567 -0.5026 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N22 mock treatment 0.336 0.00192 0.08 0.33 -0.085 -1.78 -1.2042 -0.6766 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N23 mock treatment 0.325 -0.00908 -0.36 0.329 -0.086 -1.8 -1.5248 -0.8313 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 N24 positive control 0.088 -0.246 -9.68 0.094 -0.321 -6.72 -11.5912 -0.9841 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O01 compound treatment 0.324 -0.0101 -0.4 0.333 -0.082 -1.72 -1.4935 -0.8482 2069203 IFLab1_006519 N#CCSc1nnc(c2cccs2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O02 compound treatment 0.333 -0.00108 -0.04 0.342 -0.073 -1.53 -1.1101 -0.7266 2069204 IFLab1_006520 C=CCNc1oc(Cc2cccc3ccccc23)nc1C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O03 compound treatment 0.343 0.00892 0.35 0.332 -0.083 -1.74 -0.98 -0.5532 1236685 IFLab1_006521 O=C(Nc1nc(cs1)c2ccccc2)c3cccc(c3)S(=O)(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O04 compound treatment 0.349 0.0149 0.59 0.367 -0.048 -1.0 -0.2953 -0.254 1224766 IFLab1_006522 Nc1c(oc2ccccc12)C(=O)c3ccc(F)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O05 compound treatment 0.324 -0.0101 -0.4 0.332 -0.083 -1.74 -1.5083 -0.8468 2069205 IFLab1_006523 Cc1cccc(Cn2nnc(C(=O)Nc3ccc(Br)cc3)c2N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O06 compound treatment 0.324 -0.0101 -0.4 0.332 -0.083 -1.74 -1.5083 -0.8468 2069206 IFLab1_006524 Cc1cc(C)c(NC(=O)CN2C(=O)CSCC2=O)c(C)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O07 compound treatment 0.343 0.00892 0.35 0.348 -0.067 -1.4 -0.7433 -0.5144 2069207 IFLab1_006525 Clc1ccc(cc1)S(=O)(=O)c2cc3cc(Br)ccc3oc2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O08 compound treatment 0.326 -0.00808 -0.32 0.338 -0.077 -1.61 -1.3639 -0.8306 2069208 IFLab1_006526 CCC1SC(CC)C(=O)N(CC(=O)NCc2ccccc2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O09 compound treatment 0.324 -0.0101 -0.4 0.349 -0.066 -1.38 -1.2567 -0.8748 1360347 IFLab1_006527 O=C(N1CCc2ccccc12)c3ccc(cc3)S(=O)(=O)N4CCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O10 compound treatment 0.327 -0.00708 -0.28 0.357 -0.058 -1.21 -1.0549 -0.8474 2069209 IFLab1_006528 CCOc1ccc(NC(=O)CN2C(=O)CSC(C)C2=O)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O11 compound treatment 0.324 -0.0101 -0.4 0.345 -0.07 -1.46 -1.3159 -0.8673 2069210 IFLab1_006529 CCOC(=O)Cc1csc(=S)n1c2ccc(OC)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O12 compound treatment 0.334 -8.5E-5 0.0 0.36 -0.055 -1.15 -0.8159 -0.7092 2069211 IFLab1_006530 CSC1=NCCN1S(=O)(=O)c2ccc3ccccc3c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O13 compound treatment 0.351 0.0169 0.67 0.344 -0.071 -1.49 -0.58 -0.3564 1870451 IFLab1_006531 CC(=O)OC1=C(C(N(C1=O)c2ccccn2)c3ccccc3)C(=O)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O14 compound treatment 0.34 0.00592 0.23 0.337 -0.078 -1.63 -0.9894 -0.6003 2069212 IFLab1_006532 CC(SC1=NCCN1S(=O)(=O)C)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O15 compound treatment 0.341 0.00692 0.27 0.347 -0.068 -1.42 -0.8137 -0.5618 2069213 IFLab1_006533 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)c3csc(n3)c4cccnc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O16 compound treatment 0.349 0.0149 0.59 0.35 -0.065 -1.36 -0.5469 -0.3693 2069214 IFLab1_006534 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN=C2SCc3ccc(C)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O17 compound treatment 0.341 0.00692 0.27 0.339 -0.076 -1.59 -0.932 -0.5778 2069215 IFLab1_006535 CC(Oc1ccc(Cl)c(C)c1)C(=O)N(Cc2ccccc2Cl)C3CCS(=O)(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O18 compound treatment 0.355 0.0209 0.82 0.34 -0.075 -1.57 -0.528 -0.2981 2069216 IFLab1_006536 Oc1c(sc2ncnn12)C(N3CCCCC3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O19 compound treatment 0.339 0.00492 0.19 0.333 -0.082 -1.72 -1.0764 -0.6235 2069217 IFLab1_006537 CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc2nnc(SCC=C)s2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O20 compound treatment 0.335 9.15E-4 0.04 0.338 -0.077 -1.61 -1.1136 -0.6911 2069218 IFLab1_006538 CCCSc1nnc(CSc2ncccn2)n1c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O21 compound treatment 0.337 0.00292 0.11 0.343 -0.072 -1.51 -0.9841 -0.6514 2069219 IFLab1_006539 COCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4cccc(OC)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O22 compound treatment 0.335 9.15E-4 0.04 0.336 -0.079 -1.65 -1.1432 -0.6916 2069220 IFLab1_006540 COc1cccc2c(=O)n(CC(=O)N3CCCc4ccccc34)ccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O23 mock treatment 0.322 -0.0121 -0.48 0.327 -0.088 -1.84 -1.6378 -0.8614 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 O24 positive control 0.091 -0.243 -9.56 0.097 -0.318 -6.65 -11.4634 -0.9843 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P01 compound treatment 0.332 -0.00208 -0.08 0.334 -0.081 -1.69 -1.2562 -0.7404 2069221 IFLab1_006541 Cn1cccc1Cc2nnc(SCC(=O)Nc3ccccc3)n2C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P02 mock treatment 0.317 -0.0171 -0.67 0.328 -0.087 -1.82 -1.7621 -0.9082 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P03 compound treatment 0.328 -0.00608 -0.24 0.334 -0.081 -1.69 -1.3674 -0.799 2069222 IFLab1_006542 Cc1[nH]c2ccccc2c1CCNCc3ccco3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P04 mock treatment 0.347 0.0129 0.51 0.343 -0.072 -1.51 -0.706 -0.4442 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P05 compound treatment 0.361 0.0269 1.06 0.359 -0.056 -1.17 -0.0801 -0.0507 2069223 IFLab1_006543 NNc1nc2cc3OCCOc3cc2s1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P06 mock treatment 0.35 0.0159 0.63 0.357 -0.058 -1.21 -0.4155 -0.3043 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P07 mock treatment 0.365 0.0309 1.22 0.356 -0.059 -1.23 -0.0132 -0.0076 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P08 mock treatment 0.366 0.0319 1.25 0.356 -0.059 -1.23 0.0146 0.0083 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P09 mock treatment 0.36 0.0259 1.02 0.36 -0.055 -1.15 -0.0931 -0.0606 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P10 mock treatment 0.359 0.0249 0.98 0.363 -0.052 -1.09 -0.0765 -0.0522 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P11 mock treatment 0.358 0.0239 0.94 0.353 -0.062 -1.3 -0.2522 -0.1575 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P12 mock treatment 0.36 0.0259 1.02 0.358 -0.057 -1.19 -0.1227 -0.0782 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P13 mock treatment 0.372 0.0379 1.49 0.355 -0.06 -1.26 0.1666 0.0855 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P14 mock treatment 0.352 0.0179 0.7 0.352 -0.063 -1.32 -0.4339 -0.2903 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P15 mock treatment 0.349 0.0149 0.59 0.342 -0.073 -1.53 -0.6652 -0.4066 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P16 mock treatment 0.35 0.0159 0.63 0.35 -0.065 -1.36 -0.5191 -0.3468 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P17 mock treatment 0.351 0.0169 0.67 0.351 -0.064 -1.34 -0.4765 -0.3187 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P18 mock treatment 0.349 0.0149 0.59 0.349 -0.066 -1.38 -0.5617 -0.3744 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P19 mock treatment 0.355 0.0209 0.82 0.346 -0.069 -1.44 -0.4392 -0.2644 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P20 mock treatment 0.352 0.0179 0.7 0.349 -0.066 -1.38 -0.4782 -0.3085 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P21 compound treatment 0.346 0.0119 0.47 0.347 -0.068 -1.42 -0.6747 -0.4504 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P22 mock treatment 0.342 0.00792 0.31 0.341 -0.074 -1.55 -0.8746 -0.5539 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P23 mock treatment 0.331 -0.00308 -0.12 0.336 -0.079 -1.65 -1.2544 -0.757 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1430 P24 positive control 0.094 -0.24 -9.44 0.101 -0.314 -6.57 -11.3208 -0.9843 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A01 mock treatment 0.344 0.0148 0.58 0.332 -0.00175 -0.04 0.3848 0.6612 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A02 mock treatment 0.309 -0.0202 -0.8 0.315 -0.0187 -0.39 -0.8399 -0.947 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A03 compound treatment 0.302 -0.0272 -1.07 0.309 -0.0248 -0.52 -1.1233 -0.9445 315 KBio2_000001 CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A04 compound treatment 0.322 -0.00723 -0.28 0.308 -0.0257 -0.54 -0.582 -0.9553 85 KBio2_000002 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)NC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A05 compound treatment 0.296 -0.0332 -1.31 0.296 -0.0377 -0.79 -1.4824 -0.971 29 KBio2_000003 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NCCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A06 compound treatment 0.309 -0.0202 -0.8 0.314 -0.0198 -0.41 -0.8547 -0.9535 302 KBio2_000004 CCCCC[C@H](O)C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A07 compound treatment 0.308 -0.0212 -0.83 0.3 -0.0338 -0.71 -1.0896 -0.9965 10 KBio2_000005 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A08 compound treatment 0.318 -0.0112 -0.44 0.323 -0.0107 -0.22 -0.4713 -0.9511 262 KBio2_000006 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A09 compound treatment 0.31 -0.0192 -0.76 0.306 -0.0278 -0.58 -0.9452 -0.9915 100 KBio2_000007 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)C[C@H](O)C3=C)/CCC[C@]12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A10 compound treatment 0.322 -0.00723 -0.28 0.302 -0.0318 -0.66 -0.6708 -0.9282 1000034 KBio2_000008 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A11 compound treatment 0.308 -0.0212 -0.83 0.305 -0.0288 -0.6 -1.0156 -0.9871 148 KBio2_000009 CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A12 compound treatment 0.33 7.71E-4 0.03 0.317 -0.0168 -0.35 -0.2264 -0.6436 122 KBio2_000010 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A13 compound treatment 0.323 -0.00623 -0.24 0.318 -0.0158 -0.33 -0.4062 -0.9893 150 KBio2_000011 CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A14 compound treatment 0.333 0.00377 0.15 0.303 -0.0308 -0.64 -0.3502 -0.5303 31 KBio2_000012 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A15 compound treatment 0.322 -0.00723 -0.28 0.299 -0.0348 -0.73 -0.7152 -0.916 171 KBio2_000013 CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC/C=C\CCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A16 compound treatment 0.342 0.0128 0.5 0.296 -0.0377 -0.79 -0.2035 -0.2174 33 KBio2_000014 CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A17 compound treatment 0.322 -0.00723 -0.28 0.313 -0.0208 -0.43 -0.508 -0.9789 141 KBio2_000015 CCCCC/C=C\CC1OC1C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A18 compound treatment 0.307 -0.0222 -0.87 0.302 -0.0318 -0.66 -1.0878 -0.9908 34 KBio2_000016 CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A19 compound treatment 0.329 -2.29E-4 -0.01 0.313 -0.0208 -0.43 -0.3134 -0.7216 1000003 KBio2_000017 CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A20 compound treatment 0.343 0.0138 0.54 0.336 0.00225 0.05 0.4162 0.7657 223 KBio2_000018 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A21 compound treatment 0.325 -0.00423 -0.17 0.309 -0.0248 -0.52 -0.4838 -0.8894 46 KBio2_000019 CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A22 compound treatment 0.33 7.71E-4 0.03 0.307 -0.0267 -0.56 -0.3744 -0.6678 268 KBio2_000020 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A23 mock treatment 0.312 -0.0172 -0.68 0.309 -0.0248 -0.52 -0.8452 -0.9912 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 A24 positive control 0.078 -0.251 -9.88 0.078 -0.256 -5.35 -10.769 -0.9586 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B01 mock treatment 0.331 0.00177 0.07 0.33 -0.00375 -0.08 -0.0063 -0.0596 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B02 mock treatment 0.31 -0.0192 -0.76 0.328 -0.00575 -0.12 -0.6197 -0.8095 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B03 compound treatment 0.319 -0.0102 -0.4 0.377 0.0432 0.91 0.3556 0.359 1000048 KBio2_000021 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B04 compound treatment 0.319 -0.0102 -0.4 0.42 0.0862 1.8 0.9919 0.5364 2139 KBio2_000022 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@H]32)[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B05 compound treatment 0.331 0.00177 0.07 0.426 0.0922 1.93 1.4143 0.7321 32 KBio2_000023 C/C(=C/1\C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)/O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B06 compound treatment 0.383 0.0538 2.11 0.527 0.193 4.04 4.3545 0.9542 3000451 KBio2_000024 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5cccc(O)c5cc4Cn3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B07 compound treatment 0.582 0.253 9.94 0.713 0.379 7.94 12.6393 0.9938 3000787 KBio2_000025 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B08 compound treatment 0.307 -0.0222 -0.87 0.446 0.112 2.35 1.043 0.4161 2127 KBio2_000026 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B09 compound treatment 0.325 -0.00423 -0.17 0.432 0.0983 2.06 1.3362 0.6478 35 KBio2_000027 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B10 compound treatment 0.332 0.00277 0.11 0.443 0.109 2.29 1.6936 0.74 3103826 KBio2_000028 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B11 compound treatment 0.291 -0.0382 -1.5 0.429 0.0953 1.99 0.3466 0.1388 3103827 KBio2_000029 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccc(Cl)cc2Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B12 compound treatment 0.312 -0.0172 -0.68 0.453 0.119 2.5 1.2855 0.4972 1907748 KBio2_000030 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B13 compound treatment 0.336 0.00677 0.27 0.45 0.116 2.43 1.9084 0.7798 3000452 KBio2_000031 *CCN1C(=O)[C@H](OC(=O)C)[C@@H](Sc2ccccc12)c3ccc(OC)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B14 compound treatment 0.35 0.0208 0.82 0.46 0.126 2.64 2.4456 0.8844 3000453 KBio2_000032 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B15 compound treatment 0.33 7.71E-4 0.03 0.451 0.117 2.45 1.7564 0.7158 357 KBio2_000033 Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(=O)(=O)C)cc3)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B16 compound treatment 0.329 -2.29E-4 -0.01 0.441 0.107 2.24 1.5806 0.7043 1000105 KBio2_000034 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B17 compound treatment 0.271 -0.0582 -2.29 0.392 0.0583 1.22 -0.757 -0.2918 39 KBio2_000035 Nc1c(S(=O)C(F)(F)F)c(C#N)nn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B18 compound treatment 0.33 7.71E-4 0.03 0.429 0.0953 1.99 1.4309 0.7178 1907749 KBio2_000036 CCOC(=O)CN1C(=O)CC(C[C@@H](O)C2C[C@@H](C)C[C@H](C)C2=O)CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B19 compound treatment 0.328 -0.00123 -0.05 0.403 0.0693 1.45 0.9905 0.6831 359 KBio2_000037 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B20 compound treatment 0.325 -0.00423 -0.17 0.414 0.0803 1.68 1.0699 0.634 1907750 KBio2_000038 CC[C@@H]1/C=C(\C)/C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)\C(=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC)\C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B21 compound treatment 0.338 0.00877 0.34 0.391 0.0573 1.2 1.091 0.8751 41 KBio2_000039 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B22 compound treatment 0.327 -0.00223 -0.09 0.395 0.0612 1.28 0.8443 0.6572 2349 KBio2_000040 CC12CC=C3C(CCC4=CC(=O)C=CC43C)C2CC[C@@H]1C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B23 mock treatment 0.32 -0.00923 -0.36 0.323 -0.0107 -0.22 -0.4157 -0.9736 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 B24 positive control 0.078 -0.251 -9.88 0.077 -0.257 -5.37 -10.7838 -0.959 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C01 mock treatment 0.332 0.00277 0.11 0.326 -0.00775 -0.16 -0.0376 -0.1927 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C02 mock treatment 0.312 -0.0172 -0.68 0.356 0.0222 0.47 -0.1498 -0.1822 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C03 compound treatment 0.314 -0.0152 -0.6 0.428 0.0943 1.97 0.9712 0.4712 87 KBio2_000041 CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C04 compound treatment 0.326 -0.00323 -0.13 0.425 0.0912 1.91 1.2605 0.6586 264 KBio2_000042 CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C05 compound treatment 0.327 -0.00223 -0.09 0.429 0.0953 1.99 1.3474 0.6754 301 KBio2_000043 COCCCCCCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C06 compound treatment 0.32 -0.00923 -0.36 0.424 0.0902 1.89 1.0788 0.561 233 KBio2_000044 CCCCCCCCCCC/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C07 compound treatment 0.318 -0.0112 -0.44 0.451 0.117 2.45 1.4228 0.5707 61 KBio2_000045 CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C08 compound treatment 0.318 -0.0112 -0.44 0.432 0.0983 2.06 1.1416 0.5429 256 KBio2_000046 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C09 compound treatment 0.324 -0.00523 -0.21 0.452 0.118 2.47 1.6044 0.6461 90 KBio2_000047 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C10 compound treatment 0.329 -2.29E-4 -0.01 0.458 0.124 2.6 1.8322 0.7047 221 KBio2_000048 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C11 compound treatment 0.332 0.00277 0.11 0.456 0.122 2.56 1.886 0.7366 304 KBio2_000049 CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C12 compound treatment 0.318 -0.0112 -0.44 0.451 0.117 2.45 1.4228 0.5707 260 KBio2_000050 CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C13 compound treatment 0.33 7.71E-4 0.03 0.468 0.134 2.81 2.0079 0.7147 1000009 KBio2_000051 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C14 compound treatment 0.315 -0.0142 -0.56 0.444 0.11 2.31 1.2358 0.5206 1000007 KBio2_000052 CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C15 compound treatment 0.329 -2.29E-4 -0.01 0.45 0.116 2.43 1.7138 0.7045 149 KBio2_000053 CCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C16 compound treatment 0.335 0.00577 0.23 0.433 0.0993 2.08 1.6291 0.7797 55 KBio2_000054 CC(=CCC/C(=C/CC/C(=C/CSCC(=O)O)/C)/C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C17 compound treatment 0.334 0.00477 0.19 0.448 0.114 2.39 1.8232 0.7602 143 KBio2_000055 CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C18 compound treatment 0.332 0.00277 0.11 0.438 0.104 2.18 1.6196 0.7415 217 KBio2_000056 O[C@@H](COc1cccc(c1)C(F)(F)F)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C19 compound treatment 0.334 0.00477 0.19 0.441 0.107 2.24 1.7196 0.7635 50 KBio2_000057 CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C20 compound treatment 0.323 -0.00623 -0.24 0.43 0.0963 2.01 1.251 0.6166 231 KBio2_000058 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C21 compound treatment 0.329 -2.29E-4 -0.01 0.431 0.0973 2.04 1.4326 0.704 89 KBio2_000059 CCCCC[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C22 compound treatment 0.328 -0.00123 -0.05 0.415 0.0813 1.7 1.1681 0.6867 92 KBio2_000060 CCCCC/C=C\CC1OC1CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C23 mock treatment 0.319 -0.0102 -0.4 0.333 -7.5E-4 -0.02 -0.2955 -0.7341 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 C24 positive control 0.083 -0.246 -9.68 0.078 -0.256 -5.35 -10.63 -0.9609 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D01 mock treatment 0.35 0.0208 0.82 0.342 0.00825 0.17 0.6995 0.8381 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D02 mock treatment 0.339 0.00977 0.38 0.351 0.0173 0.36 0.5269 0.9995 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D03 compound treatment 0.315 -0.0142 -0.56 0.375 0.0413 0.86 0.2148 0.2088 43 KBio2_000061 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D04 compound treatment 0.114 -0.215 -8.46 0.227 -0.107 -2.23 -7.5634 -0.8642 1531 KBio2_000062 O=c1n([se]c2ccccc12)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D05 compound treatment 0.296 -0.0332 -1.31 0.397 0.0633 1.32 0.0121 0.0065 3104253 KBio2_000063 CC(CCCN1CCC2(CC1)N(C)CNC2=O)c3ccc(F)cc3.Fc1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D06 compound treatment 0.333 0.00377 0.15 0.448 0.114 2.39 1.7954 0.7495 1875 KBio2_000064 FC(F)(F)c1ccccc1n2ccnc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D07 compound treatment 0.342 0.0128 0.5 0.456 0.122 2.56 2.164 0.8301 3000569 KBio2_000065 Cc1cc(C(=O)c2ccccc2Cc3ccccc3)c(C)[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D08 compound treatment 0.341 0.0118 0.46 0.458 0.124 2.6 2.1658 0.8201 2372 KBio2_000066 COc1cc(ccc1OC(F)F)c2ccc(=O)[nH]n2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D09 compound treatment 0.32 -0.00923 -0.36 0.443 0.109 2.29 1.36 0.5875 70 KBio2_000067 CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D10 compound treatment 0.337 0.00777 0.31 0.462 0.128 2.68 2.1138 0.7826 3000570 KBio2_000068 CCCNc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D11 compound treatment 0.342 0.0128 0.5 0.462 0.128 2.68 2.2528 0.8251 72 KBio2_000069 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D12 compound treatment 0.338 0.00877 0.34 0.458 0.124 2.6 2.0824 0.7939 3000571 KBio2_000070 *C1=C[C@]2(CC)CCCN3CCc4c(C32)n1c5ccccc45 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D13 compound treatment 0.35 0.0208 0.82 0.472 0.138 2.89 2.6232 0.8726 74 KBio2_000071 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D14 compound treatment 0.32 -0.00923 -0.36 0.491 0.157 3.29 2.0703 0.6253 2337 KBio2_000072 COc1cc2CCn3c(cc(=Nc4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D15 compound treatment 0.332 0.00277 0.11 0.447 0.113 2.37 1.7528 0.7388 76 KBio2_000073 CC1(C)[C@@H](O)C[C@@H]2[C@]1(O)[C@H](O)C[C@@]3(C[C@@](C)(O)C4CC[C@H]3[C@@]2(C)O)[C@@H]4O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D16 compound treatment 0.332 0.00277 0.11 0.434 0.1 2.1 1.5604 0.7428 1907751 KBio2_000074 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D17 compound treatment 0.313 -0.0162 -0.64 0.451 0.117 2.45 1.2838 0.5064 78 KBio2_000075 C[C@]1(Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O)C3CCCC3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D18 compound treatment 0.335 0.00577 0.23 0.45 0.116 2.43 1.8806 0.7697 1000092 KBio2_000076 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D19 compound treatment 0.306 -0.0232 -0.91 0.444 0.11 2.31 0.9856 0.3972 3103683 KBio2_000077 COc1ccccc1.CS[C@H](C)[C@H](OC(=O)C)C(=O)N(C)CCN(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D20 compound treatment 0.337 0.00777 0.31 0.452 0.118 2.47 1.9658 0.7884 2270 KBio2_000078 CCCCOc1cc(CC2CNC(=O)N2)ccc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D21 compound treatment 0.334 0.00477 0.19 0.437 0.103 2.16 1.6604 0.7656 362 KBio2_000079 CCN(CC)CC(=O)Nc1c(C)cccc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D22 compound treatment 0.352 0.0228 0.9 0.439 0.105 2.2 2.1905 0.9213 1865 KBio2_000080 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D23 mock treatment 0.316 -0.0132 -0.52 0.332 -0.00175 -0.04 -0.3937 -0.755 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 D24 positive control 0.081 -0.248 -9.76 0.078 -0.256 -5.35 -10.6856 -0.96 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E01 mock treatment 0.338 0.00877 0.34 0.342 0.00825 0.17 0.3659 0.9488 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E02 mock treatment 0.318 -0.0112 -0.44 0.344 0.0103 0.21 -0.1605 -0.327 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E03 compound treatment 0.329 -2.29E-4 -0.01 0.429 0.0953 1.99 1.4031 0.7039 308 KBio2_000081 CCCCC/C=C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E04 compound treatment 0.324 -0.00523 -0.21 0.437 0.103 2.16 1.3824 0.6369 94 KBio2_000082 CCCCCC1OC1C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E05 compound treatment 0.343 0.0138 0.54 0.438 0.104 2.18 1.9255 0.8566 147 KBio2_000083 CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E06 compound treatment 0.325 -0.00423 -0.17 0.437 0.103 2.16 1.4102 0.6508 1000018 KBio2_000084 CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E07 compound treatment 0.332 0.00277 0.11 0.451 0.117 2.45 1.812 0.7378 259 KBio2_000085 CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E08 compound treatment 0.329 -2.29E-4 -0.01 0.455 0.121 2.54 1.7878 0.7046 3000590 KBio2_000086 **(*)S[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E09 compound treatment 0.347 0.0178 0.7 0.433 0.0993 2.08 1.9627 0.8957 272 KBio2_000087 OC(=O)CCCCCCCCCCCCCCCC#C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E10 compound treatment 0.349 0.0198 0.78 0.46 0.126 2.64 2.4178 0.8779 3000609 KBio2_000088 *C(=O)[C@H](CS)NS[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E11 compound treatment 0.342 0.0128 0.5 0.458 0.124 2.6 2.1936 0.8284 300 KBio2_000089 O[C@@H](CCc1ccccc1)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E12 compound treatment 0.351 0.0218 0.86 0.453 0.119 2.5 2.3698 0.8983 3000610 KBio2_000090 *[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E13 compound treatment 0.323 -0.00623 -0.24 0.443 0.109 2.29 1.4434 0.6278 109 KBio2_000091 CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E14 compound treatment 0.335 0.00577 0.23 0.442 0.108 2.27 1.7622 0.7741 22 KBio2_000092 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E15 compound treatment 0.322 -0.00723 -0.28 0.436 0.102 2.14 1.312 0.6078 179 KBio2_000093 CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E16 compound treatment 0.342 0.0128 0.5 0.434 0.1 2.1 1.8385 0.8523 270 KBio2_000094 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E17 compound treatment 0.318 -0.0112 -0.44 0.424 0.0902 1.89 1.0232 0.5276 81 KBio2_000095 CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E18 compound treatment 0.342 0.0128 0.5 0.447 0.113 2.37 2.0308 0.8383 229 KBio2_000096 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E19 compound treatment 0.308 -0.0212 -0.83 0.424 0.0902 1.89 0.7452 0.3609 183 KBio2_000097 CCCCCCCCCCCCCCCCOCC(CO)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E20 compound treatment 0.335 0.00577 0.23 0.441 0.107 2.24 1.7474 0.7746 186 KBio2_000098 CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E21 compound treatment 0.319 -0.0102 -0.4 0.414 0.0803 1.68 0.9031 0.523 181 KBio2_000099 CCCCCCCCCCCCCCCCOCC(CO)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E22 compound treatment 0.345 0.0158 0.62 0.432 0.0983 2.06 1.8923 0.8812 3000631 KBio2_000100 *P(=O)OC[C@H](NC(=O)CCCCCCCCCCCCCCC)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E23 mock treatment 0.318 -0.0112 -0.44 0.329 -0.00475 -0.1 -0.3825 -0.8451 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 E24 positive control 0.082 -0.247 -9.72 0.082 -0.252 -5.27 -10.5986 -0.9586 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F01 mock treatment 0.338 0.00877 0.34 0.338 0.00425 0.09 0.3067 0.8613 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F02 mock treatment 0.313 -0.0162 -0.64 0.336 0.00225 0.05 -0.4179 -0.6532 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F03 compound treatment 0.318 -0.0112 -0.44 0.404 0.0703 1.47 0.7273 0.4738 80 KBio2_000101 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F04 compound treatment 0.322 -0.00723 -0.28 0.429 0.0953 1.99 1.2084 0.6002 3000632 KBio2_000102 *CCNS(=O)(=O)c1cccc2c(Cl)cccc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F05 compound treatment 0.325 -0.00423 -0.17 0.421 0.0872 1.83 1.1735 0.6401 372 KBio2_000103 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F06 compound treatment 0.331 0.00177 0.07 0.427 0.0933 1.95 1.4291 0.7319 47 KBio2_000104 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F07 compound treatment 0.324 -0.00523 -0.21 0.44 0.106 2.22 1.4268 0.639 82 KBio2_000105 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F08 compound treatment 0.346 0.0168 0.66 0.44 0.106 2.22 2.0385 0.879 3000633 KBio2_000106 Cc1ccc(C(=O)*2****o2)c3nc4c(C(=O)*5****o5)c(N)c(=O)c(C)c4oc13 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F09 compound treatment 0.325 -0.00423 -0.17 0.449 0.115 2.41 1.5878 0.6568 84 KBio2_000107 Nc1cc(nc(N)[n+]1OS(=O)(=O)O)N2CCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F10 compound treatment 0.291 -0.0382 -1.5 0.403 0.0693 1.45 -0.0381 -0.0183 1907752 KBio2_000108 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCc1ccc(O)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F11 compound treatment 0.296 -0.0332 -1.31 0.405 0.0712 1.49 0.1305 0.0658 86 KBio2_000109 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F12 compound treatment 0.343 0.0138 0.54 0.473 0.139 2.91 2.4434 0.8244 331 KBio2_000110 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F13 compound treatment 0.187 -0.142 -5.59 0.31 -0.0238 -0.5 -4.3057 -0.7669 110 KBio2_000111 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F14 compound treatment 0.294 -0.0352 -1.39 0.446 0.112 2.35 0.6815 0.2499 333 KBio2_000112 NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F15 compound treatment 0.341 0.0118 0.46 0.451 0.117 2.45 2.0622 0.8259 112 KBio2_000113 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F16 compound treatment 0.377 0.0478 1.88 0.492 0.158 3.31 3.6698 0.9639 203 KBio2_000114 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F17 compound treatment 0.234 -0.0952 -3.74 0.366 0.0323 0.67 -2.1704 -0.5705 907431 KBio2_000115 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F18 compound treatment 0.585 0.256 10.06 0.705 0.371 7.77 12.6044 0.9919 3 KBio2_000116 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F19 compound treatment 0.342 0.0128 0.5 0.455 0.121 2.54 2.1492 0.8309 115 KBio2_000117 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F20 compound treatment 0.402 0.0728 2.86 0.476 0.142 2.98 4.1281 0.9998 208 KBio2_000118 CC(C)(C)c1cc(/C=C(\C#N)/C(=S)N)cc(c1O)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F21 compound treatment 0.349 0.0198 0.78 0.426 0.0922 1.93 1.9147 0.9201 117 KBio2_000119 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F22 compound treatment 0.323 -0.00623 -0.24 0.395 0.0612 1.28 0.7331 0.5618 2413 KBio2_000120 CC(C)CC(NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C)C(C)C)C(=O)NC(C)(C)C(=O)N2CCCC2C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CO)Cc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F23 mock treatment 0.318 -0.0112 -0.44 0.312 -0.0217 -0.46 -0.634 -0.9999 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 F24 positive control 0.082 -0.247 -9.72 0.081 -0.253 -5.29 -10.6134 -0.9591 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G01 mock treatment 0.333 0.00377 0.15 0.348 0.0143 0.3 0.3157 0.948 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G02 mock treatment 0.322 -0.00723 -0.28 0.326 -0.00775 -0.16 -0.3157 -0.9646 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G03 compound treatment 0.331 0.00177 0.07 0.412 0.0783 1.64 1.2071 0.7365 83 KBio2_000121 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G04 compound treatment 0.317 -0.0122 -0.48 0.411 0.0772 1.62 0.8031 0.4762 191 KBio2_000122 CCCc1c(O)c(ccc1OCCCCc2nnn[nH]2)C(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G05 compound treatment 0.317 -0.0122 -0.48 0.4 0.0663 1.39 0.6403 0.4364 173 KBio2_000123 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G06 compound treatment 0.33 7.71E-4 0.03 0.43 0.0963 2.01 1.4457 0.7177 3000641 KBio2_000124 *CCOP(=O)(O)OC[C@H](O)COCCCCCCCCCCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G07 compound treatment 0.315 -0.0142 -0.56 0.439 0.105 2.2 1.1618 0.5113 177 KBio2_000125 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G08 compound treatment 0.325 -0.00423 -0.17 0.441 0.107 2.24 1.4694 0.6529 111 KBio2_000126 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G09 compound treatment 0.332 0.00277 0.11 0.45 0.116 2.43 1.7972 0.738 175 KBio2_000127 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G10 compound treatment 0.314 -0.0152 -0.6 0.426 0.0922 1.93 0.9416 0.4659 36 KBio2_000128 CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G11 compound treatment 0.314 -0.0152 -0.6 0.436 0.102 2.14 1.0896 0.4904 102 KBio2_000129 C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G12 compound treatment 0.31 -0.0192 -0.76 0.423 0.0892 1.87 0.786 0.3901 1000002 KBio2_000130 CCCCCCCCCCCCCC(=O)N[C@@H](C)[C@H](O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G13 compound treatment 0.326 -0.00323 -0.13 0.451 0.117 2.45 1.6452 0.6696 98 KBio2_000131 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G14 compound treatment 0.313 -0.0162 -0.64 0.453 0.119 2.5 1.3134 0.5099 227 KBio2_000132 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G15 compound treatment 0.311 -0.0182 -0.72 0.43 0.0963 2.01 0.9174 0.4291 118 KBio2_000133 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G16 compound treatment 0.312 -0.0172 -0.68 0.429 0.0953 1.99 0.9304 0.442 8 KBio2_000134 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G17 compound treatment 0.316 -0.0132 -0.52 0.452 0.118 2.47 1.382 0.5465 276 KBio2_000135 CCCCCCCCCCCCCCC(F)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G18 compound treatment 0.334 0.00477 0.19 0.442 0.108 2.27 1.7344 0.763 136 KBio2_000136 COC(C)(C)CCCC(C)C/C=C/C(=C/C(=O)O)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G19 compound treatment 0.334 0.00477 0.19 0.43 0.0963 2.01 1.5569 0.7696 274 KBio2_000137 CCCCCCCCCCCCC(O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G20 compound treatment 0.336 0.00677 0.27 0.422 0.0882 1.85 1.4941 0.8008 310 KBio2_000138 CCCCC(C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G21 compound treatment 0.332 0.00277 0.11 0.413 0.0793 1.66 1.2497 0.7519 130 KBio2_000139 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G22 compound treatment 0.322 -0.00723 -0.28 0.339 0.00525 0.11 -0.1233 -0.4046 309 KBio2_000140 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G23 mock treatment 0.311 -0.0182 -0.72 0.322 -0.0118 -0.25 -0.6807 -0.8983 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 G24 positive control 0.082 -0.247 -9.72 0.08 -0.254 -5.31 -10.6282 -0.9595 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H01 mock treatment 0.342 0.0128 0.5 0.34 0.00625 0.13 0.4475 0.8625 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H02 mock treatment 0.322 -0.00723 -0.28 0.329 -0.00475 -0.1 -0.2713 -0.9009 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H03 compound treatment 0.325 -0.00423 -0.17 0.39 0.0563 1.18 0.7148 0.6012 119 KBio2_000141 OC(=O)c1ccccc1Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H04 compound treatment 0.339 0.00977 0.38 0.42 0.0862 1.8 1.5479 0.8388 556 KBio2_000142 COc1cc2ncc(nc2cc1OC)c3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H05 compound treatment 0.617 0.288 11.31 0.688 0.354 7.41 13.2425 0.979 3001877 KBio2_000143 OC(=O)c1cc(O)ccc1NCCCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H06 compound treatment 0.323 -0.00623 -0.24 0.428 0.0943 1.97 1.2214 0.6146 3001878 KBio2_000144 Cc1[nH]c(=O)c([N+]#[C-])cc1c2ccncc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H07 compound treatment 0.321 -0.00823 -0.32 0.423 0.0892 1.87 1.0919 0.576 2450 KBio2_000145 Oc1ccc(cc1n2c(=O)[nH]c3cc(ccc23)C(F)(F)F)C(F)(F)F 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H08 compound treatment 0.326 -0.00323 -0.13 0.451 0.117 2.45 1.6452 0.6696 2080829 KBio2_000146 OCC1(CO)N2CCC(CC2)C1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H09 compound treatment 0.346 0.0168 0.66 0.48 0.146 3.06 2.6303 0.8402 124 KBio2_000147 CC(C)(O)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@H](Cc5c4[nH]c6ccccc56)CC[C@@]3(O)C2=CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H10 compound treatment 0.339 0.00977 0.38 0.485 0.151 3.17 2.5097 0.7872 1907753 KBio2_000148 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H11 compound treatment 0.335 0.00577 0.23 0.45 0.116 2.43 1.8806 0.7697 126 KBio2_000149 CC1(C)Oc2ccc(C#N)cc2[C@@H](OC3=CC(=O)CC3)[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H12 compound treatment 0.381 0.0518 2.04 0.485 0.151 3.17 3.6774 0.9772 354 KBio2_000150 Nc1ccc2C(=O)NC(=O)c3cccc1c32 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H13 compound treatment 0.333 0.00377 0.15 0.424 0.0902 1.89 1.4403 0.7603 128 KBio2_000151 CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H14 compound treatment 0.342 0.0128 0.5 0.444 0.11 2.31 1.9864 0.8413 445 KBio2_000152 NC(=O)c1cccc(N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H15 compound treatment 0.349 0.0198 0.78 0.463 0.129 2.7 2.4622 0.8749 2474 KBio2_000153 Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H16 compound treatment 0.335 0.00577 0.23 0.455 0.121 2.54 1.9546 0.7673 1907754 KBio2_000154 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H17 compound treatment 0.333 0.00377 0.15 0.436 0.102 2.14 1.6178 0.7543 153 KBio2_000155 CC1=CC=C(CC1)N(CC2=NCCN2)c3cccc(O)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H18 compound treatment 0.316 -0.0132 -0.52 0.426 0.0922 1.93 0.9972 0.4988 3001880 KBio2_000156 CC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H19 compound treatment 0.334 0.00477 0.19 0.43 0.0963 2.01 1.5569 0.7696 3001155 KBio2_000157 CC1(C)NC(=O)NC1=O.c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H20 compound treatment 0.338 0.00877 0.34 0.432 0.0983 2.06 1.6977 0.8143 154 KBio2_000158 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H21 compound treatment 0.268 -0.0612 -2.41 0.341 0.00725 0.15 -1.595 -0.6612 156 KBio2_000159 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H22 compound treatment 0.367 0.0378 1.49 0.417 0.0833 1.74 2.282 0.9968 401 KBio2_000160 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H23 mock treatment 0.318 -0.0112 -0.44 0.32 -0.0138 -0.29 -0.5157 -0.9785 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 H24 positive control 0.084 -0.245 -9.64 0.082 -0.252 -5.27 -10.543 -0.9596 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I01 mock treatment 0.323 -0.00623 -0.24 0.327 -0.00675 -0.14 -0.2731 -0.9658 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I02 mock treatment 0.328 -0.00123 -0.05 0.353 0.0193 0.4 0.2507 0.6178 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I03 compound treatment 0.326 -0.00323 -0.13 0.392 0.0583 1.22 0.7722 0.63 299 KBio2_000161 CCCCCCCCCCOCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I04 compound treatment 0.339 0.00977 0.38 0.413 0.0793 1.66 1.4443 0.8484 184 KBio2_000162 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)C)C(=O)O)[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I05 compound treatment 0.333 0.00377 0.15 0.437 0.103 2.16 1.6326 0.7539 13 KBio2_000163 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I06 compound treatment 0.33 7.71E-4 0.03 0.414 0.0803 1.68 1.2089 0.7198 14 KBio2_000164 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I07 compound treatment 0.323 -0.00623 -0.24 0.46 0.126 2.64 1.695 0.6388 64 KBio2_000165 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)OO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I08 compound treatment 0.33 7.71E-4 0.03 0.456 0.122 2.56 1.8304 0.7154 123 KBio2_000166 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I09 compound treatment 0.345 0.0158 0.62 0.461 0.127 2.66 2.3214 0.849 137 KBio2_000167 CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I10 compound treatment 0.34 0.0108 0.42 0.465 0.131 2.75 2.2416 0.8066 40 KBio2_000168 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I11 compound treatment 0.334 0.00477 0.19 0.454 0.12 2.52 1.912 0.7577 146 KBio2_000169 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I12 compound treatment 0.333 0.00377 0.15 0.464 0.13 2.73 2.0322 0.7445 66 KBio2_000170 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I13 compound treatment 0.356 0.0268 1.05 0.471 0.137 2.87 2.7752 0.9072 144 KBio2_000171 CCCCCCCCC#CCC#CCC#CCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I14 compound treatment 0.33 7.71E-4 0.03 0.484 0.15 3.14 2.2447 0.7139 69 KBio2_000172 CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I15 compound treatment 0.305 -0.0242 -0.95 0.486 0.152 3.19 1.5792 0.4749 145 KBio2_000173 CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I16 compound treatment 0.318 -0.0112 -0.44 0.45 0.116 2.43 1.408 0.5695 318 KBio2_000174 CCCCCCCCCCCCCCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I17 compound treatment 0.341 0.0118 0.46 0.449 0.115 2.41 2.0326 0.8277 120 KBio2_000175 O=Cc1c2[nH]c3ccccc3c2cc4[nH]c5ccccc5c14 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I18 compound treatment 0.338 0.00877 0.34 0.425 0.0912 1.91 1.5941 0.8215 114 KBio2_000176 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I19 compound treatment 0.288 -0.0412 -1.62 0.434 0.1 2.1 0.3372 0.1272 257 KBio2_000177 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I20 compound treatment 0.34 0.0108 0.42 0.425 0.0912 1.91 1.6497 0.8434 190 KBio2_000178 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I21 compound treatment 0.332 0.00277 0.11 0.392 0.0583 1.22 0.939 0.7672 258 KBio2_000179 CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I22 compound treatment 0.327 -0.00223 -0.09 0.36 0.0262 0.55 0.3264 0.5869 212 KBio2_000180 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I23 mock treatment 0.326 -0.00323 -0.13 0.326 -0.00775 -0.16 -0.2045 -0.9927 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 I24 positive control 0.086 -0.243 -9.56 0.082 -0.252 -5.27 -10.4874 -0.9605 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J01 mock treatment 0.34 0.0108 0.42 0.33 -0.00375 -0.08 0.244 0.5664 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J02 mock treatment 0.334 0.00477 0.19 0.345 0.0113 0.24 0.2991 0.9937 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J03 compound treatment 0.34 0.0108 0.42 0.371 0.0372 0.78 0.8506 0.9589 3104408 KBio2_000181 CC(N/C(=N\C#N)/Nc1ccncc1)C(C)(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J04 compound treatment 0.332 0.00277 0.11 0.405 0.0712 1.49 1.1313 0.7568 1907755 KBio2_000182 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J05 compound treatment 0.332 0.00277 0.11 0.39 0.0563 1.18 0.9094 0.7693 2431 KBio2_000183 CCN(CC)CCNC(=O)c1ccc(N)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J06 compound treatment 0.345 0.0158 0.62 0.428 0.0943 1.97 1.8331 0.8866 1907756 KBio2_000184 Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J07 compound treatment 0.318 -0.0112 -0.44 0.432 0.0983 2.06 1.1416 0.5429 3104409 KBio2_000185 CCCNCC(O)COc1ccccc1.CC(=O)CCc1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J08 compound treatment 0.36 0.0308 1.21 0.492 0.158 3.31 3.1971 0.9068 155 KBio2_000186 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J09 compound treatment 0.335 0.00577 0.23 0.459 0.125 2.62 2.0138 0.7655 161 KBio2_000187 COc1ccc2nccc(C(O)[C@H]3CC4CC[C@@H]3CC4C=C)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J10 compound treatment 0.323 -0.00623 -0.24 0.434 0.1 2.1 1.3102 0.6203 361 KBio2_000188 CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J11 compound treatment 0.326 -0.00323 -0.13 0.432 0.0983 2.06 1.364 0.6622 1000050 KBio2_000189 COc1ccc2nccc([C@@H](O)[C@@H]3CC4CC[C@@H]3CC4C=C)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J12 compound treatment 0.332 0.00277 0.11 0.439 0.105 2.2 1.6344 0.7412 3103962 KBio2_000190 CO[C@H]1/C=C/C=C(\C)/C[C@@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@H]2C[C@@H](O)[C@H](C)[C@H](O2)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J13 compound treatment 0.339 0.00977 0.38 0.439 0.105 2.2 1.829 0.8181 907369 KBio2_000191 CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J14 compound treatment 0.361 0.0318 1.25 0.48 0.146 3.06 3.0474 0.9219 3103963 KBio2_000192 CC(=O)OCOC(=O)CNc1ccccc1OCCOc2ccccc2NCC(=O)OCOC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J15 compound treatment 0.348 0.0188 0.74 0.477 0.143 3.0 2.6416 0.8556 3103964 KBio2_000193 CC(C)[C@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@]1(C)[C@]5(O)C[C@@]3(C)[C@@]6(O)CC[C@H](C)[C@@H](O)[C@]46O5 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J16 compound treatment 0.422 0.0928 3.65 0.567 0.233 4.88 6.0306 0.9897 3103618 KBio2_000194 Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J17 compound treatment 0.26 -0.0692 -2.72 0.405 0.0712 1.49 -0.8704 -0.2805 165 KBio2_000195 OC(COc1cccc2[nH]c(C#N)cc12)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J18 compound treatment 0.345 0.0158 0.62 0.444 0.11 2.31 2.0698 0.8664 3001881 KBio2_000196 */C=C(/CC(=O)O)\C=C\[C@@H](C)C\C=C\CC/C=C/C=C\CC/C(=C\C=C(\*)/C)/C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J19 compound treatment 0.306 -0.0232 -0.91 0.397 0.0633 1.32 0.2901 0.1804 390 KBio2_000197 COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J20 compound treatment 0.358 0.0288 1.13 0.462 0.128 2.68 2.6976 0.9262 1000439 KBio2_000198 CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(I)cc4)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J21 compound treatment 0.314 -0.0152 -0.6 0.404 0.0703 1.47 0.6161 0.3881 193 KBio2_000199 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J22 compound treatment 0.345 0.0158 0.62 0.397 0.0633 1.32 1.3744 0.9403 3104702 KBio2_000200 C[C@H]1CCC/C=C/C2C[C@H](O)C[C@H]2[C@H](O)/C=C/C(=O)O1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J23 mock treatment 0.321 -0.00823 -0.32 0.319 -0.0147 -0.31 -0.447 -0.9997 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 J24 positive control 0.086 -0.243 -9.56 0.083 -0.251 -5.25 -10.4726 -0.9601 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K01 mock treatment 0.348 0.0188 0.74 0.348 0.0143 0.3 0.7327 0.9205 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K02 mock treatment 0.337 0.00777 0.31 0.329 -0.00475 -0.1 0.1458 0.4537 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K03 compound treatment 0.324 -0.00523 -0.21 0.366 0.0323 0.67 0.3318 0.4703 139 KBio2_000201 CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K04 compound treatment 0.33 7.71E-4 0.03 0.393 0.0592 1.24 0.8982 0.7242 214 KBio2_000202 CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)O)C(=O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K05 compound treatment 0.326 -0.00323 -0.13 0.39 0.0563 1.18 0.7426 0.6272 1000033 KBio2_000203 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K06 compound treatment 0.35 0.0208 0.82 0.444 0.11 2.31 2.2089 0.9025 216 KBio2_000204 CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K07 compound treatment 0.344 0.0148 0.58 0.444 0.11 2.31 2.042 0.8583 57 KBio2_000205 CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K08 compound treatment 0.343 0.0138 0.54 0.448 0.114 2.39 2.0734 0.8458 218 KBio2_000206 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K09 compound treatment 0.339 0.00977 0.38 0.431 0.0973 2.04 1.7107 0.826 88 KBio2_000207 CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K10 compound treatment 0.33 7.71E-4 0.03 0.463 0.129 2.7 1.934 0.715 220 KBio2_000208 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K11 compound treatment 0.32 -0.00923 -0.36 0.419 0.0853 1.78 1.0049 0.552 45 KBio2_000209 CCCCCCCC/C=C\CCCCCCCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K12 compound treatment 0.324 -0.00523 -0.21 0.445 0.111 2.33 1.5008 0.6422 222 KBio2_000210 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K13 compound treatment 0.345 0.0158 0.62 0.44 0.106 2.22 2.0107 0.8711 1000028 KBio2_000211 CCCCC[C@H](O)/C=C/[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K14 compound treatment 0.335 0.00577 0.23 0.478 0.144 3.02 2.2949 0.7581 226 KBio2_000212 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K15 compound treatment 0.35 0.0208 0.82 0.449 0.115 2.41 2.2828 0.8965 1000027 KBio2_000213 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H](O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K16 compound treatment 0.346 0.0168 0.66 0.456 0.122 2.56 2.2752 0.8612 224 KBio2_000214 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K17 compound treatment 0.348 0.0188 0.74 0.468 0.134 2.81 2.5084 0.8636 1000008 KBio2_000215 C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K18 compound treatment 0.342 0.0128 0.5 0.446 0.112 2.35 2.016 0.8393 3184 KBio2_000216 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K19 compound treatment 0.348 0.0188 0.74 0.449 0.115 2.41 2.2272 0.8831 47 KBio2_000217 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K20 compound treatment 0.344 0.0148 0.58 0.437 0.103 2.16 1.9385 0.8664 267 KBio2_000218 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K21 compound treatment 0.315 -0.0142 -0.56 0.413 0.0793 1.66 0.7771 0.444 266 KBio2_000219 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K22 compound treatment 0.34 0.0108 0.42 0.431 0.0973 2.04 1.7385 0.8363 104 KBio2_000220 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K23 mock treatment 0.32 -0.00923 -0.36 0.34 0.00625 0.13 -0.1641 -0.4255 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 K24 positive control 0.086 -0.243 -9.56 0.085 -0.249 -5.21 -10.443 -0.9591 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L01 mock treatment 0.349 0.0198 0.78 0.352 0.0182 0.38 0.8197 0.9464 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L02 mock treatment 0.332 0.00277 0.11 0.33 -0.00375 -0.08 0.0215 0.1605 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L03 compound treatment 0.34 0.0108 0.42 0.353 0.0193 0.4 0.5843 0.9997 194 KBio2_000221 CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L04 compound treatment 0.371 0.0418 1.64 0.406 0.0722 1.51 2.2304 0.9991 407 KBio2_000222 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L05 compound treatment 0.33 7.71E-4 0.03 0.371 0.0372 0.78 0.5726 0.734 392 KBio2_000223 CCN(CC)CCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L06 compound treatment 0.327 -0.00223 -0.09 0.393 0.0592 1.24 0.8148 0.6555 3103965 KBio2_000224 Nc1ncnc2n(C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)c(Br)nc12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L07 compound treatment 0.329 -2.29E-4 -0.01 0.407 0.0732 1.53 1.0775 0.7029 196 KBio2_000225 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L08 compound treatment 0.343 0.0138 0.54 0.422 0.0882 1.85 1.6887 0.8775 3103966 KBio2_000226 NC1=NC2C(N=C(Br)N2C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)C(=O)N1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L09 compound treatment 0.342 0.0128 0.5 0.41 0.0762 1.6 1.4833 0.8868 198 KBio2_000227 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L10 compound treatment 0.354 0.0248 0.97 0.439 0.105 2.2 2.2461 0.9327 404 KBio2_000228 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L11 compound treatment 0.347 0.0178 0.7 0.41 0.0762 1.6 1.6223 0.9314 3103746 KBio2_000229 C1CCC(CC1)/N=C(\NC2C3CC4CC(C3)CC2C4)/N5CCOCC5 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L12 compound treatment 0.371 0.0418 1.64 0.433 0.0993 2.08 2.6299 0.9932 3001884 KBio2_000230 CCNC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L13 compound treatment 0.337 0.00777 0.31 0.43 0.0963 2.01 1.6403 0.8052 396 KBio2_000231 CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L14 compound treatment 0.315 -0.0142 -0.56 0.451 0.117 2.45 1.3394 0.5322 373 KBio2_000232 CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L15 compound treatment 0.34 0.0108 0.42 0.453 0.119 2.5 2.064 0.8154 1000056 KBio2_000233 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L16 compound treatment 0.35 0.0208 0.82 0.449 0.115 2.41 2.2828 0.8965 3103967 KBio2_000234 CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L17 compound treatment 0.354 0.0248 0.97 0.457 0.123 2.58 2.5124 0.9113 200 KBio2_000235 COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@@]3(C[C@@]6(O)C7CN8CC(C)CCC8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L18 compound treatment 0.409 0.0798 3.14 0.501 0.167 3.5 4.6926 0.9985 1907757 KBio2_000236 Oc1ccc(NC2=C(C(=O)NC2=O)c3ccccc3[N+](=O)[O-])cc1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L19 compound treatment 0.334 0.00477 0.19 0.438 0.104 2.18 1.6752 0.7651 202 KBio2_000237 COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L20 compound treatment 0.31 -0.0192 -0.76 0.396 0.0623 1.3 0.3865 0.2566 3103968 KBio2_000238 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L21 compound treatment 0.312 -0.0172 -0.68 0.418 0.0843 1.76 0.7677 0.4064 3104544 KBio2_000239 CC(O)(C(=O)Nc1ccccc1)C(F)(F)F.CS(=O)(=O)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L22 compound treatment 0.141 -0.188 -7.4 0.226 -0.108 -2.25 -6.8275 -0.8825 125 KBio2_000240 COc1cc(O)c2c(=O)c(OC)c(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5c(CC(C)OC(=O)c6ccccc6)c(OC)c(=O)c7c(O)cc(OC)c(c1c24)c75 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L23 mock treatment 0.324 -0.00523 -0.21 0.331 -0.00275 -0.06 -0.1861 -0.8715 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 L24 positive control 0.088 -0.241 -9.48 0.085 -0.249 -5.21 -10.3874 -0.9601 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M01 mock treatment 0.335 0.00577 0.23 0.341 0.00725 0.15 0.2677 0.9808 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M02 mock treatment 0.35 0.0208 0.82 0.344 0.0103 0.21 0.7291 0.8635 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M03 compound treatment 0.35 0.0208 0.82 0.346 0.0123 0.26 0.7587 0.8864 53 KBio2_000241 CC(=CCC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M04 compound treatment 0.335 0.00577 0.23 0.364 0.0302 0.63 0.6081 0.9042 189 KBio2_000242 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M05 compound treatment 0.332 0.00277 0.11 0.351 0.0173 0.36 0.3323 0.8813 51 KBio2_000243 CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)/C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M06 compound treatment 0.326 -0.00323 -0.13 0.378 0.0442 0.93 0.565 0.6045 49 KBio2_000244 COC(=O)[C@@H](N)CSC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M07 compound treatment 0.346 0.0168 0.66 0.401 0.0673 1.41 1.4614 0.9403 116 KBio2_000245 Cc1c(nn(c1c2ccc(I)cc2)c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M08 compound treatment 0.35 0.0208 0.82 0.4 0.0663 1.39 1.5578 0.9682 1000032 KBio2_000246 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M09 compound treatment 0.33 7.71E-4 0.03 0.402 0.0683 1.43 1.0313 0.7219 132 KBio2_000247 CC1(C)CCC(C)(C)c2cc(ccc21)C(=O)Nc3ccc(cc3)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M10 compound treatment 0.337 0.00777 0.31 0.401 0.0673 1.41 1.2112 0.841 3103969 KBio2_000248 OC(=O)CCC/C=C\CC1C(CNNC(=O)Nc2ccccc2)C3CCC1O3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M11 compound treatment 0.331 0.00177 0.07 0.403 0.0693 1.45 1.0739 0.7402 2 KBio2_000249 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M12 compound treatment 0.355 0.0258 1.01 0.434 0.1 2.1 2.1999 0.9443 3001885 KBio2_000250 CCCCCc1cc(O)c2C3C=C(CC[C@H]3C(C)(C)Oc2c1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M13 compound treatment 0.33 7.71E-4 0.03 0.427 0.0933 1.95 1.4013 0.718 4 KBio2_000251 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M14 compound treatment 0.337 0.00777 0.31 0.492 0.158 3.31 2.5577 0.7691 134 KBio2_000252 C/C(=C\c1ccc(cc1)C(=O)O)/c2ccc3c(c2)C(C)(C)CCC3(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M15 compound treatment 0.322 -0.00723 -0.28 0.46 0.126 2.64 1.6671 0.6274 316 KBio2_000253 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M16 compound treatment 0.353 0.0238 0.93 0.437 0.103 2.16 2.1887 0.9297 261 KBio2_000254 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H]2CO[C@@H]1C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M17 compound treatment 0.323 -0.00623 -0.24 0.423 0.0892 1.87 1.1475 0.6092 6 KBio2_000255 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)NCCO 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M18 compound treatment 0.334 0.00477 0.19 0.403 0.0693 1.45 1.1573 0.792 3103970 KBio2_000256 CCCCC/C=C\CC(O)/C=C/c1cccc(CC(O)CCCCO)n1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M19 compound treatment 0.32 -0.00923 -0.36 0.403 0.0693 1.45 0.7681 0.5142 20 KBio2_000257 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M20 compound treatment 0.346 0.0168 0.66 0.406 0.0722 1.51 1.5354 0.9308 18 KBio2_000258 Cc1c(C(=O)c2ccc3ccccc3c2)c4cccc5OC[C@@H](CN6CCOCC6)n1c54 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M21 compound treatment 0.352 0.0228 0.9 0.385 0.0512 1.07 1.3914 0.996 225 KBio2_000259 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M22 compound treatment 0.34 0.0108 0.42 0.35 0.0163 0.34 0.5399 0.9941 138 KBio2_000260 Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M23 mock treatment 0.328 -0.00123 -0.05 0.318 -0.0158 -0.33 -0.2672 -0.8022 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 M24 positive control 0.09 -0.239 -9.41 0.087 -0.247 -5.16 -10.3022 -0.9601 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N01 mock treatment 0.334 0.00477 0.19 0.332 -0.00175 -0.04 0.1067 0.5585 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N02 mock treatment 0.343 0.0138 0.54 0.343 0.00925 0.19 0.5197 0.9039 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N03 compound treatment 0.331 0.00177 0.07 0.335 0.00125 0.03 0.0677 0.9106 1002014 KBio2_000261 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)CCl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N04 compound treatment 0.365 0.0358 1.41 0.377 0.0432 0.91 1.6345 0.9773 3103971 KBio2_000262 COC[C@H]([C@@H](O)[C@@H](O)C(=O)NCC[C@@H](C)c1nc(/C=C/C[C@H]2OC3(C[C@H](O)[C@H]2C)OC([C@@H](C[C@@H](O)[C@@H](C)[C@@H](O)[C@@H](C)/C=C(\C)/C(=C/C=C/C(=C\C#N)/C)/C)OC)[C@@H](OP(=O)(O)O)C3(C)C)co1)N(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N05 compound treatment 0.4 0.0708 2.78 0.41 0.0762 1.6 3.0959 0.9652 2041 KBio2_000263 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N06 compound treatment 0.358 0.0288 1.13 0.389 0.0553 1.16 1.6174 0.9999 3001887 KBio2_000264 CC[C@@]1(O)C(=O)OCc2c1cc3Cc4nc5ccccc5cc4-n3c2=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N07 compound treatment 0.337 0.00777 0.31 0.362 0.0283 0.59 0.6341 0.9528 831924 KBio2_000265 O=C[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)OCc3ccccc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N08 compound treatment 0.346 0.0168 0.66 0.392 0.0583 1.22 1.3282 0.9584 363 KBio2_000266 CC12C3CCC(O3)C2(C)C(=O)OC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N09 compound treatment 0.354 0.0248 0.97 0.409 0.0752 1.57 1.8022 0.9733 1907758 KBio2_000267 CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N10 compound treatment 0.344 0.0148 0.58 0.385 0.0512 1.07 1.169 0.9585 446 KBio2_000268 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N11 compound treatment 0.358 0.0288 1.13 0.408 0.0742 1.55 1.8986 0.9878 1891 KBio2_000269 Clc1oc(=O)c2ccccc2c1Cl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N12 compound treatment 0.343 0.0138 0.54 0.415 0.0813 1.7 1.5851 0.8883 377 KBio2_000270 Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N13 compound treatment 0.333 0.00377 0.15 0.43 0.0963 2.01 1.5291 0.7571 1907759 KBio2_000271 CC(C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N14 compound treatment 0.359 0.0298 1.17 0.441 0.107 2.24 2.4147 0.9539 379 KBio2_000272 O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N15 compound treatment 0.346 0.0168 0.66 0.443 0.109 2.29 2.0828 0.8754 2060 KBio2_000273 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N16 compound treatment 0.41 0.0808 3.18 0.499 0.165 3.46 4.6908 0.9991 3103975 KBio2_000274 CCCN(CCC)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCC)CCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N17 compound treatment 0.335 0.00577 0.23 0.395 0.0612 1.28 1.0668 0.8195 1907760 KBio2_000275 C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)CCl 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N18 compound treatment 0.324 -0.00523 -0.21 0.374 0.0403 0.84 0.4502 0.5193 391 KBio2_000276 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N19 compound treatment 0.328 -0.00123 -0.05 0.348 0.0143 0.3 0.1767 0.5849 1907761 KBio2_000277 CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N20 compound treatment 0.357 0.0278 1.09 0.361 0.0273 0.57 1.1753 0.9541 3001890 KBio2_000278 COc1ccc2c(c1)c(OC)[n+](C)c3c2ccc4cc5OCOc5cc43 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N21 compound treatment 0.353 0.0238 0.93 0.344 0.0103 0.21 0.8125 0.8474 1907762 KBio2_000279 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C)C=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N22 compound treatment 0.356 0.0268 1.05 0.346 0.0123 0.26 0.9255 0.8543 1907763 KBio2_000280 Oc1ccc(/C=C/C(=O)OCCc2ccccc2)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N23 mock treatment 0.327 -0.00223 -0.09 0.325 -0.00875 -0.18 -0.1915 -0.9431 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 N24 positive control 0.09 -0.239 -9.41 0.088 -0.246 -5.14 -10.2874 -0.9596 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O01 mock treatment 0.333 0.00377 0.15 0.335 0.00125 0.03 0.1233 0.8192 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O02 mock treatment 0.343 0.0138 0.54 0.337 0.00325 0.07 0.4309 0.7897 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O03 compound treatment 0.343 0.0138 0.54 0.342 0.00825 0.17 0.5049 0.8885 73 KBio2_000281 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O04 compound treatment 0.344 0.0148 0.58 0.334 2.5E-4 0.01 0.4144 0.7134 338 KBio2_000282 Nc1ccncc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O05 compound treatment 0.34 0.0108 0.42 0.346 0.0123 0.26 0.4807 0.9711 12 KBio2_000283 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCOCC4)c2c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O06 compound treatment 0.341 0.0118 0.46 0.341 0.00725 0.15 0.4345 0.8922 340 KBio2_000284 CCCCCC(O)CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O07 compound treatment 0.339 0.00977 0.38 0.344 0.0103 0.21 0.4233 0.9621 305 KBio2_000285 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O08 compound treatment 0.352 0.0228 0.9 0.368 0.0343 0.72 1.1399 0.9939 1000039 KBio2_000286 CC[C@]1(COC)[C@H](O)C[C@H](OC)[C@@]2(C(C)C)C3C[C@@]4(O)[C@H](OC(=O)c5ccccc5)C3[C@](C[C@H](OC)C12)(OC(=O)C)[C@@H](O)C[C@@H]4OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O09 compound treatment 0.338 0.00877 0.34 0.337 0.00325 0.07 0.2919 0.8306 307 KBio2_000287 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O10 compound treatment 0.339 0.00977 0.38 0.345 0.0113 0.24 0.4381 0.9724 24 KBio2_000288 CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc2ccc(NS(=O)(=O)C)cc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O11 compound treatment 0.331 0.00177 0.07 0.33 -0.00375 -0.08 -0.0063 -0.0596 311 KBio2_000289 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O12 compound treatment 0.356 0.0268 1.05 0.36 0.0262 0.55 1.1327 0.954 1000040 KBio2_000290 [N-2]C1(CC2CC3CC(C2)C1)C3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O13 compound treatment 0.329 -2.29E-4 -0.01 0.331 -0.00275 -0.06 -0.0471 -0.808 313 KBio2_000291 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O14 compound treatment 0.356 0.0268 1.05 0.362 0.0283 0.59 1.1623 0.9628 1000042 KBio2_000292 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O15 compound treatment 0.349 0.0198 0.78 0.347 0.0133 0.28 0.7457 0.9036 271 KBio2_000293 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2C/C(=C\CCCC(=O)O)/C[C@H]12 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O16 compound treatment 0.339 0.00977 0.38 0.325 -0.00875 -0.18 0.1422 0.3341 26 KBio2_000294 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O17 compound treatment 0.339 0.00977 0.38 0.345 0.0113 0.24 0.4381 0.9724 140 KBio2_000295 CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O18 compound treatment 0.345 0.0158 0.62 0.34 0.00625 0.13 0.5309 0.8378 28 KBio2_000296 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O19 compound treatment 0.338 0.00877 0.34 0.34 0.00625 0.13 0.3363 0.9119 142 KBio2_000297 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O20 compound treatment 0.399 0.0698 2.74 0.395 0.0612 1.28 2.8461 0.94 3103889 KBio2_000298 COC(=O)C1=C(C)NC(=C(O)C1c2ccccc2C(F)(F)F)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O21 compound treatment 0.347 0.0178 0.7 0.338 0.00425 0.09 0.557 0.7907 219 KBio2_000299 O[C@@H](COc1cccc(Cl)c1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O22 compound treatment 0.347 0.0178 0.7 0.343 0.00925 0.19 0.6309 0.8702 3103678 KBio2_000300 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O23 mock treatment 0.325 -0.00423 -0.17 0.321 -0.0127 -0.27 -0.3062 -0.9741 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 O24 positive control 0.093 -0.236 -9.29 0.09 -0.244 -5.1 -10.1744 -0.9602 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P01 mock treatment 0.334 0.00477 0.19 0.341 0.00725 0.15 0.2399 0.9945 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P02 mock treatment 0.341 0.0118 0.46 0.349 0.0153 0.32 0.5529 0.9835 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P03 compound treatment 0.334 0.00477 0.19 0.321 -0.0127 -0.27 -0.056 -0.1718 1907764 KBio2_000301 CCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2OC)[C@@H](C)OC1=O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P04 compound treatment 0.352 0.0228 0.9 0.357 0.0233 0.49 0.9771 0.9589 393 KBio2_000302 CC(C)NCC(O)c1ccc(N)c(C#N)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P05 compound treatment 0.332 0.00277 0.11 0.337 0.00325 0.07 0.1251 0.9743 2090 KBio2_000303 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P06 compound treatment 0.384 0.0548 2.15 0.38 0.0462 0.97 2.2071 0.9348 157 KBio2_000304 COC(=O)CC[C@H](NC(=O)CNC(=O)c1ccc(/C=C/C(=O)OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P07 compound treatment 0.353 0.0238 0.93 0.363 0.0293 0.61 1.0937 0.9789 2020 KBio2_000305 CCCCCCCCCCC1=C(C)C(=O)C(=C(OC)C1=O)OC 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P08 compound treatment 0.376 0.0468 1.84 0.396 0.0623 1.3 2.2214 0.9857 395 KBio2_000306 C(Oc1ccccc1C2CC2)C3=NCCN3 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P09 compound treatment 0.412 0.0828 3.25 0.412 0.0783 1.64 3.4591 0.9495 3103891 KBio2_000307 CC(=C)C1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P10 compound treatment 0.379 0.0498 1.96 0.388 0.0543 1.14 2.1865 0.9665 448 KBio2_000308 Clc1cccc(Cl)c1N=C2NCCN2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P11 compound treatment 0.374 0.0448 1.76 0.393 0.0592 1.24 2.1214 0.9853 1000476 KBio2_000309 C[C@@H](N(C)CC#C)c1ccccc1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P12 compound treatment 0.384 0.0548 2.15 0.406 0.0722 1.51 2.5918 0.985 417 KBio2_000310 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P13 compound treatment 0.383 0.0538 2.11 0.405 0.0712 1.49 2.5492 0.9854 410 KBio2_000311 CC(=N)NCc1cccc(CN)c1 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P14 compound treatment 0.51 0.181 7.11 0.503 0.169 3.54 7.5302 0.9483 3001893 KBio2_000312 COc1ccc(/C=C/C(=O)CC(=O)\C=C\c2cccc(O)c2OC)cc1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P15 compound treatment 0.365 0.0358 1.41 0.385 0.0512 1.07 1.7529 0.991 3001894 KBio2_000313 *[C@@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)[C@H](*)[C@H](C)CCCC.CC(=O)C[C@@H](CC(=O)O)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P16 compound treatment 0.359 0.0298 1.17 0.368 0.0343 0.72 1.3345 0.9723 421 KBio2_000314 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](O)CC2CC(=O)NC(=O)C2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P17 compound treatment 0.369 0.0398 1.56 0.368 0.0343 0.72 1.6125 0.9374 2340 KBio2_000315 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P18 compound treatment 0.351 0.0218 0.86 0.362 0.0283 0.59 1.0233 0.9837 3001895 KBio2_000316 *C1N(C)C(=O)C(*)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C(=O)C(CC)NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(*)N(C)C1=O)C(C)C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P19 compound treatment 0.339 0.00977 0.38 0.336 0.00225 0.05 0.3049 0.7879 1907765 KBio2_000317 Cc1coc-2c1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P20 compound treatment 0.347 0.0178 0.7 0.329 -0.00475 -0.1 0.4238 0.6005 397 KBio2_000318 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P21 compound treatment 0.344 0.0148 0.58 0.343 0.00925 0.19 0.5475 0.8944 3103893 KBio2_000319 C[C@H]([C@@H]1O[C@@H](C[C@@H]2CC[C@@H](C)[C@@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)[C@@H]5O[C@H](C[C@@H]5C)[C@H]6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)O2)CC[C@@H]1C)C(=O)O 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P22 compound treatment 0.362 0.0328 1.29 0.347 0.0133 0.28 1.1072 0.84 3103894 KBio2_000320 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]4[C@H](O)C1=C 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P23 mock treatment 0.343 0.0138 0.54 0.341 0.00725 0.15 0.4901 0.8717 1017.0009 EnzCoupledColor(1017.0009) TrypanothioneReductase 1017.0009.1464 P24 positive control 0.097 -0.232 -9.13 0.093 -0.241 -5.04 -10.0188 -0.9607