ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A01 compound treatment 0.211 -0.0201 -2.78 0.212 -0.0137 -1.98 -3.3648 -0.986 1205993 ChemDiv3_000001 Cc1cc(c(O)c(c1)C(C)(C)C)n2nc3ccc(Cl)cc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A02 compound treatment 0.223 -0.00813 -1.12 0.222 -0.00369 -0.53 -1.1712 -0.9418 1044707 ChemDiv3_000002 OC(=O)c1ccccc1C(=O)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A03 compound treatment 0.214 -0.0171 -2.37 0.206 -0.0197 -2.84 -3.6846 -0.9958 1699093 ChemDiv3_000003 Cc1ccc(Nc2ccc3ncnc4-c5ccccc5C(=O)c2c43)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A04 compound treatment 0.261 0.0299 4.13 0.254 0.0283 4.09 5.8094 1.0 3117569 ChemDiv3_000004 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A05 compound treatment 0.312 0.0809 11.17 0.316 0.0903 13.05 17.124 0.997 1561677 ChemDiv3_000005 CCOC(=O)c1c(O)nc2c3ccccc3oc2c1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A06 compound treatment 0.256 0.0249 3.44 0.254 0.0283 4.09 5.321 0.9962 3117570 ChemDiv3_000006 CN(C)C(=O)C[n+]1ccc(/C=N/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A07 compound treatment 0.225 -0.00613 -0.85 0.213 -0.0127 -1.83 -1.895 -0.9386 1166193 ChemDiv3_000007 CCCC1CCC(CC1)c2ccc(cc2)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A08 compound treatment 0.456 0.225 31.07 0.454 0.228 32.98 45.2862 0.9996 3019825 ChemDiv3_000008 C(c1ccccc1)[n+]2ccc(cc2)c3nc4ccccc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A09 compound treatment 0.24 0.00887 1.22 0.247 0.0213 3.08 3.043 0.9184 1640201 ChemDiv3_000009 CCCc1ccc(OC(=O)c2ccc(O)cc2Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A10 compound treatment 0.225 -0.00613 -0.85 0.23 0.00431 0.62 -0.1587 -0.1509 1305993 ChemDiv3_000010 Cc1sc(N)nc1C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A11 compound treatment 0.213 -0.0181 -2.51 0.206 -0.0197 -2.84 -3.7823 -0.998 3019826 ChemDiv3_000011 CCN1C(=O)/C(=C/C=C\2/Sc3ccccc3N2CC)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A12 compound treatment 0.217 -0.0141 -1.95 0.212 -0.0137 -1.98 -2.7787 -1.0 1005107 ChemDiv3_000012 CC(C)(C)C(=O)C[n+]1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A13 compound treatment 0.344 0.113 15.59 0.339 0.113 16.37 22.5992 0.9997 1917998 ChemDiv3_000013 CN(C)c1ccc(cc1)c2n(C)c3ccccc3[n+]2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A14 compound treatment 0.233 0.00187 0.26 0.233 0.00731 1.06 0.9292 0.8546 3117571 ChemDiv3_000014 O/N=C/c1cc[n+](C/C=C\c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A15 compound treatment 0.232 8.67E-4 0.12 0.236 0.0103 1.49 1.138 0.7615 1511477 ChemDiv3_000015 Cc1ccc(cc1)S(=O)(=O)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A16 compound treatment 0.209 -0.0221 -3.06 0.205 -0.0207 -2.99 -4.2751 -0.9999 1463254 ChemDiv3_000016 C(CN1CCOCC1)Oc2ccc3ccccc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A17 compound treatment 0.214 -0.0171 -2.37 0.209 -0.0167 -2.41 -3.3781 -1.0 1289110 ChemDiv3_000017 N#CC(=c1ccc(=C(C#N)c2ccc(cc2)N3CCCC3)cc1)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A18 compound treatment 0.21 -0.0211 -2.92 0.21 -0.0157 -2.27 -3.6668 -0.9921 1594677 ChemDiv3_000018 CC(C)CN(CC(C)C)Cn1c(=O)oc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A19 compound treatment 0.229 -0.00213 -0.29 0.222 -0.00369 -0.53 -0.585 -0.9611 1914297 ChemDiv3_000019 COc1ccc(/C=N/n2cnnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A20 compound treatment 0.251 0.0199 2.74 0.249 0.0233 3.37 4.3218 0.9948 1550111 ChemDiv3_000020 CC(C)C1CCC(C)C(C(O)c2ccc(cc2)c3ccccc3)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A21 compound treatment 0.276 0.0449 6.2 0.279 0.0533 7.7 9.8282 0.9942 3019827 ChemDiv3_000021 CN(C)c1ccc(/C=C/C=C/c2cc[n+](C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A22 compound treatment 0.245 0.0139 1.92 0.237 0.0113 1.63 2.51 0.9969 1470588 ChemDiv3_000022 Fc1ccccc1C(=O)Oc2cccc(OC(=O)c3ccccc3F)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A23 mock treatment 0.219 -0.0121 -1.68 0.217 -0.00869 -1.25 -2.0726 -0.9898 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 A24 positive control 0.216 -0.0151 -2.09 0.217 -0.00869 -1.25 -2.3657 -0.9702 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B01 compound treatment 0.239 0.00787 1.09 0.237 0.0113 1.63 1.9239 0.9804 3117572 ChemDiv3_000023 COc1ccc(/C=N/c2ccc(OCC(O)CN3C(C)CCCC3C)cc2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B02 compound treatment 0.224 -0.00713 -0.99 0.22 -0.00569 -0.82 -1.2778 -0.9959 1476169 ChemDiv3_000024 CC(C)(C)NC(=O)C1(CC2CC3C1)CC(C2)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B03 compound treatment 0.244 0.0129 1.78 0.225 -6.88E-4 -0.1 1.1867 0.6666 1164812 ChemDiv3_000025 O(c1ccccc1)c2cccc(Oc3ccccc3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B04 compound treatment 0.227 -0.00413 -0.57 0.218 -0.00769 -1.11 -1.189 -0.9522 3019828 ChemDiv3_000026 Brc1ccc(/C=N/C2CCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B05 compound treatment 0.356 0.125 17.25 0.358 0.132 19.11 25.7121 0.9987 2083946 ChemDiv3_000027 O=C(/C=C/c1ccccc1)/C=C/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B06 compound treatment 0.268 0.0369 5.09 0.264 0.0383 5.53 7.5146 0.9991 3117574 ChemDiv3_000028 CC1(CC2(C)CC3(C)C1)CC(C/N=C/c4ccc(O)cc4)(C2)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B07 compound treatment 0.23 -0.00113 -0.16 0.222 -0.00369 -0.53 -0.4873 -0.8778 1666537 ChemDiv3_000029 COC(=O)NCC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B08 compound treatment 0.236 0.00487 0.67 0.232 0.00631 0.91 1.1202 0.9888 1021487 ChemDiv3_000030 C1CN(CCN1c2ccccn2)c3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B09 compound treatment 0.243 0.0119 1.64 0.23 0.00431 0.62 1.5997 0.9122 3019829 ChemDiv3_000031 COc1ccc(/C=N/c2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B10 compound treatment 0.226 -0.00513 -0.71 0.221 -0.00469 -0.68 -0.9802 -0.9997 1699181 ChemDiv3_000032 Cc1c(NC(=O)c2ccccc2)c(=O)n(c3ccccc3)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B11 compound treatment 0.22 -0.0111 -1.54 0.219 -0.00669 -0.97 -1.7706 -0.9749 3019830 ChemDiv3_000033 CC(C)Cc1ccc(cc1)C(C)C(=O)NC(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B12 compound treatment 0.249 0.0179 2.47 0.245 0.0193 2.79 3.7179 0.9981 3117575 ChemDiv3_000034 COc1ccc(/C=C/2\CC/C(=C\c3ccc(C)cc3)/C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B13 compound treatment 0.228 -0.00313 -0.43 0.226 3.12E-4 0.05 -0.2742 -0.63 1119180 ChemDiv3_000035 CNC(=O)c1ccc(Oc2ccc(cc2)C(=O)NC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B14 compound treatment 0.263 0.0319 4.4 0.248 0.0223 3.22 5.3919 0.9882 1616129 ChemDiv3_000036 CC(=O)Nc1cccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(Oc5ccc(C)c(C)c5)cc4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B15 compound treatment 0.303 0.0719 9.93 0.298 0.0723 10.45 14.4064 0.9997 1336672 ChemDiv3_000037 O=C(Nc1cc(=O)c2ccccc2o1)OCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B16 compound treatment 0.232 8.67E-4 0.12 0.223 -0.00269 -0.39 -0.1898 -0.4673 3117576 ChemDiv3_000038 CC[n+]1ccc(C)c2cc(ccc12)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B17 compound treatment 0.278 0.0469 6.47 0.288 0.0623 9.0 10.9428 0.9869 3019831 ChemDiv3_000039 NNC(=S)NC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B18 compound treatment 0.228 -0.00313 -0.43 0.222 -0.00369 -0.53 -0.6827 -0.9947 1270265 ChemDiv3_000040 Clc1ccc(cc1)S(=O)(=O)n2cnc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B19 compound treatment 0.231 -1.33E-4 -0.02 0.226 3.12E-4 0.05 0.0189 0.3875 3117577 ChemDiv3_000041 Cc1cc(nc2ccc3ccccc3c12)c4ccc5ccccc5n4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B20 compound treatment 0.236 0.00487 0.67 0.234 0.00831 1.2 1.3244 0.9624 1591919 ChemDiv3_000042 CNc1ccc(cc1)S(=O)(=O)c2ccc(NC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B21 compound treatment 0.321 0.0899 12.42 0.303 0.0773 11.17 16.6754 0.9986 3117578 ChemDiv3_000043 O=C(C1=C(C(=O)c2ccccc2C1=O)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B22 compound treatment 0.225 -0.00613 -0.85 0.218 -0.00769 -1.11 -1.3843 -0.9911 1583295 ChemDiv3_000044 Brc1ccc(OC(=O)c2cccnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B23 mock treatment 0.234 0.00287 0.4 0.224 -0.00169 -0.24 0.1077 0.2316 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 B24 positive control 0.23 -0.00113 -0.16 0.224 -0.00169 -0.24 -0.2831 -0.9771 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C01 compound treatment 0.225 -0.00613 -0.85 0.226 3.12E-4 0.05 -0.5672 -0.6685 3019835 ChemDiv3_000045 Cc1ccn(CN2CCN(Cn3ccc(C)n3)C2=S)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C02 compound treatment 0.228 -0.00313 -0.43 0.225 -6.88E-4 -0.1 -0.3763 -0.8473 1183514 ChemDiv3_000046 CC(=O)Oc1ccc(C(=O)c2ccccc2)c(OC(=O)C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C03 compound treatment 0.239 0.00787 1.09 0.238 0.0123 1.78 2.0261 0.9721 1699403 ChemDiv3_000047 O=C(NC1(CCC(=O)O1)C(=O)OCc2ccccc2)OCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C04 compound treatment 0.241 0.00987 1.36 0.234 0.00831 1.2 1.8129 0.998 3019836 ChemDiv3_000048 COc1ccc(NC(=S)C)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C05 compound treatment 0.235 0.00387 0.53 0.227 0.00131 0.19 0.5118 0.9029 3019837 ChemDiv3_000049 Clc1ccc(OC(=O)c2ccc(Br)cc2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C06 compound treatment 0.267 0.0359 4.96 0.265 0.0393 5.68 7.519 0.9977 3117579 ChemDiv3_000050 CC(C)N(C(C)C)C(=O)C[n+]1ccc(/C=N/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C07 compound treatment 0.232 8.67E-4 0.12 0.229 0.00331 0.48 0.423 0.8576 1112119 ChemDiv3_000051 CC(=O)Oc1ccc(cc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C08 compound treatment 0.276 0.0449 6.2 0.271 0.0453 6.55 9.0111 0.9996 1921020 ChemDiv3_000052 CC[n+]1cccc(c1)c2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C09 compound treatment 0.236 0.00487 0.67 0.234 0.00831 1.2 1.3244 0.9624 1233273 ChemDiv3_000053 CCN1CCN(CC1)c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C10 compound treatment 0.219 -0.0121 -1.68 0.222 -0.00369 -0.53 -1.5619 -0.888 3019838 ChemDiv3_000054 NC(=O)N1CCc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C11 compound treatment 0.222 -0.00913 -1.26 0.221 -0.00469 -0.68 -1.371 -0.9574 1021994 ChemDiv3_000055 Oc1ccc(cc1)C2(CCCCC2)c3ccc(O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C12 compound treatment 0.226 -0.00513 -0.71 0.221 -0.00469 -0.68 -0.9802 -0.9997 3019839 ChemDiv3_000056 CC(C)(C)OC(=O)C[n+]1cccc(c1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C13 compound treatment 0.226 -0.00513 -0.71 0.225 -6.88E-4 -0.1 -0.5717 -0.7983 3117584 ChemDiv3_000057 O=C1CN(C(=O)N1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C14 compound treatment 0.268 0.0369 5.09 0.265 0.0393 5.68 7.6167 0.9985 3019840 ChemDiv3_000058 O/N=C/c1cc[n+](CC(=O)N2CCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C15 compound treatment 0.223 -0.00813 -1.12 0.222 -0.00369 -0.53 -1.1712 -0.9418 1320550 ChemDiv3_000059 COC(=O)CCS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)CCC(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C16 compound treatment 0.469 0.238 32.86 0.458 0.232 33.56 46.9647 0.9999 1778026 ChemDiv3_000060 OCc1c(CO)[n+]([O-])c2ccccc2[n+]1[O-] 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C17 compound treatment 0.371 0.14 19.32 0.367 0.141 20.41 28.0967 0.9996 3019841 ChemDiv3_000061 Cc1ccc(cc1)C(=O)C2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C18 compound treatment 0.266 0.0349 4.82 0.267 0.0413 5.97 7.6256 0.9944 1353751 ChemDiv3_000062 Clc1cccc(NCn2c(=O)oc3ccccc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C19 compound treatment 0.246 0.0149 2.05 0.245 0.0193 2.79 3.4248 0.9887 1912422 ChemDiv3_000063 CCc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C20 compound treatment 0.217 -0.0141 -1.95 0.217 -0.00869 -1.25 -2.268 -0.9772 1318161 ChemDiv3_000064 C(N1CCOCCN(Cc2ccccc2)CCOCC1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C21 compound treatment 0.377 0.146 20.15 0.371 0.145 20.99 29.0914 0.9998 1038768 ChemDiv3_000065 CCN(CC)c1ccc2c(C)cc(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C22 compound treatment 0.268 0.0369 5.09 0.26 0.0343 4.96 7.106 0.9999 3019842 ChemDiv3_000066 O=C(Oc1ccc(cc1)c2ccccc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C23 mock treatment 0.233 0.00187 0.26 0.224 -0.00169 -0.24 0.01 0.0282 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 C24 positive control 0.233 0.00187 0.26 0.227 0.00131 0.19 0.3164 0.9886 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D01 compound treatment 0.222 -0.00913 -1.26 0.226 3.12E-4 0.05 -0.8603 -0.6814 3117585 ChemDiv3_000067 C(Sc1nnnn1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D02 compound treatment 0.222 -0.00913 -1.26 0.219 -0.00669 -0.97 -1.5753 -0.9913 3117586 ChemDiv3_000068 CC(C)(C)C(/C=C/c1ccc(Cl)cc1Cl)n2nnnc2C(C)(C)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D03 compound treatment 0.223 -0.00813 -1.12 0.223 -0.00269 -0.39 -1.069 -0.8992 1053376 ChemDiv3_000069 OC(=O)C1C(C(C1c2ccccc2)C(=O)O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D04 compound treatment 0.236 0.00487 0.67 0.243 0.0173 2.5 2.2437 0.8664 3117587 ChemDiv3_000070 O=C(/C=C/N1C(=O)c2ccccc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D05 compound treatment 0.22 -0.0111 -1.54 0.217 -0.00869 -1.25 -1.9749 -0.9949 3019843 ChemDiv3_000071 c1cncc(c1)c2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D06 compound treatment 0.222 -0.00913 -1.26 0.22 -0.00569 -0.82 -1.4731 -0.9784 1343691 ChemDiv3_000072 CCN(C)CC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D07 compound treatment 0.227 -0.00413 -0.57 0.223 -0.00269 -0.39 -0.6783 -0.9823 1187732 ChemDiv3_000073 COC(=O)NC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D08 compound treatment 0.316 0.0849 11.72 0.312 0.0863 12.47 17.1062 0.9995 1355186 ChemDiv3_000074 Nc1ccc(Sc2ccc3ccccc3c2Cl)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D09 compound treatment 0.222 -0.00913 -1.26 0.215 -0.0107 -1.54 -1.9838 -0.995 1016949 ChemDiv3_000075 NC(=N)NC(=N)NCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D10 compound treatment 0.224 -0.00713 -0.99 0.223 -0.00269 -0.39 -0.9713 -0.9171 1392304 ChemDiv3_000076 Clc1ccc(cc1)c2nnc(o2)C3CCC(CC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D11 compound treatment 0.227 -0.00413 -0.57 0.225 -6.88E-4 -0.1 -0.474 -0.8178 1388409 ChemDiv3_000077 S=c1sc2ccccc2n1CN3CCN(Cc4ccccc4)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D12 compound treatment 0.233 0.00187 0.26 0.231 0.00531 0.77 0.725 0.8955 3117588 ChemDiv3_000078 COc1ccc(/C=C/2\CC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D13 compound treatment 0.312 0.0809 11.17 0.304 0.0783 11.31 15.8984 1.0 1025986 ChemDiv3_000079 Cc1ccccc1NC(=O)c2cc3ccccc3cc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D14 compound treatment 0.221 -0.0101 -1.4 0.223 -0.00269 -0.39 -1.2644 -0.8703 1513086 ChemDiv3_000080 O=C(COc1ccc2ccccc2c1)NS(=O)(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D15 compound treatment 0.219 -0.0121 -1.68 0.214 -0.0117 -1.69 -2.379 -1.0 1550944 ChemDiv3_000081 O=C(N1CC(CC1=O)c2ccccc2)c3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D16 compound treatment 0.255 0.0239 3.3 0.265 0.0393 5.68 6.3468 0.9666 1432699 ChemDiv3_000082 CCOC(=O)c1cccc(n1)C(=O)Nc2nc3ccc(OC)cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D17 compound treatment 0.248 0.0169 2.33 0.24 0.0143 2.07 3.1095 0.9982 1601789 ChemDiv3_000083 Cc1ccc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D18 compound treatment 0.23 -0.00113 -0.16 0.227 0.00131 0.19 0.0233 0.0949 3019844 ChemDiv3_000084 CC(C)OC(=O)n1c(=S)oc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D19 compound treatment 0.229 -0.00213 -0.29 0.225 -6.88E-4 -0.1 -0.2786 -0.8959 1581559 ChemDiv3_000085 O=C(Oc1ccc(OC(=O)c2ccccc2)cc1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D20 compound treatment 0.311 0.0799 11.03 0.308 0.0823 11.89 16.2093 0.9993 3117589 ChemDiv3_000086 O=S(=O)(/C=C/c1ccccc1)N2C=Cc3ccccc3C2c4c[nH]c5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D21 compound treatment 0.322 0.0909 12.55 0.327 0.101 14.63 19.2244 0.9971 1529969 ChemDiv3_000087 Nc1nnc(s1)C(=O)c2ccccc2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D22 compound treatment 0.23 -0.00113 -0.16 0.228 0.00231 0.33 0.1255 0.3401 1119404 ChemDiv3_000088 CCCC1CCC(CC1)c2ccc(OC(=O)c3cccnc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D23 mock treatment 0.229 -0.00213 -0.29 0.227 0.00131 0.19 -0.0743 -0.2121 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 D24 positive control 0.234 0.00287 0.4 0.227 0.00131 0.19 0.4141 0.9431 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E01 compound treatment 0.223 -0.00813 -1.12 0.231 0.00531 0.77 -0.2519 -0.1851 3019845 ChemDiv3_000089 C1OC(OCC2OC(OC12)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E02 compound treatment 0.219 -0.0121 -1.68 0.217 -0.00869 -1.25 -2.0726 -0.9898 1616713 ChemDiv3_000090 CCCOc1ccc(N)cc1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E03 compound treatment 0.23 -0.00113 -0.16 0.229 0.00331 0.48 0.2276 0.4521 3117590 ChemDiv3_000091 COc1ccc(cc1OC)C(=O)CN2Cc3ccccc3C2=N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E04 compound treatment 0.22 -0.0111 -1.54 0.217 -0.00869 -1.25 -1.9749 -0.9949 3019846 ChemDiv3_000092 COc1ccc(NC(=O)C)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E05 compound treatment 0.478 0.247 34.1 0.47 0.244 35.29 49.0695 0.9999 3019847 ChemDiv3_000093 Nc1nc(cc[n+]1[O-])c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E06 compound treatment 0.266 0.0349 4.82 0.26 0.0343 4.96 6.9107 0.9999 3117591 ChemDiv3_000094 O/N=C/c1cc[n+](CC(=O)NC2CCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E07 compound treatment 0.231 -1.33E-4 -0.02 0.226 3.12E-4 0.05 0.0189 0.3875 1701731 ChemDiv3_000095 CCc1ccc(cc1)C(=O)Oc2ccc(C#N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E08 compound treatment 0.227 -0.00413 -0.57 0.224 -0.00169 -0.24 -0.5761 -0.9279 1069596 ChemDiv3_000096 COC(=O)N1C(C=Cc2ccccc12)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E09 compound treatment 0.245 0.0139 1.92 0.238 0.0123 1.78 2.6122 0.9993 3019848 ChemDiv3_000097 N/N=C/c1ccc(cc1)S(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E10 compound treatment 0.221 -0.0101 -1.4 0.219 -0.00669 -0.97 -1.673 -0.9836 3117592 ChemDiv3_000098 CN1CCN(CC1)C(=O)/C=C(/C)\C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E11 compound treatment 0.273 0.0419 5.78 0.275 0.0493 7.12 9.1266 0.9947 1026004 ChemDiv3_000099 COc1ccc2ccccc2c1c3c(OC)ccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E12 compound treatment 0.225 -0.00613 -0.85 0.219 -0.00669 -0.97 -1.2822 -0.9979 3019849 ChemDiv3_000100 CC(C)(C)C(=O)C[n+]1cccc(c1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E13 compound treatment 0.228 -0.00313 -0.43 0.217 -0.00869 -1.25 -1.1934 -0.899 1049039 ChemDiv3_000101 CC(=O)N(Nc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E14 compound treatment 0.219 -0.0121 -1.68 0.219 -0.00669 -0.97 -1.8683 -0.9657 3117593 ChemDiv3_000102 O/N=C/c1ccc[n+](CC(=O)NC2(CC3CC4CC(C3)C2)C4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E15 compound treatment 0.224 -0.00713 -0.99 0.219 -0.00669 -0.97 -1.3799 -1.0 3019850 ChemDiv3_000103 CSc1ccc(cc1)c2ccc(SC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E16 compound treatment 0.223 -0.00813 -1.12 0.221 -0.00469 -0.68 -1.2733 -0.9706 3019851 ChemDiv3_000104 Nc1ccc(cc1)S(=O)(=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E17 compound treatment 0.224 -0.00713 -0.99 0.223 -0.00269 -0.39 -0.9713 -0.9171 1913805 ChemDiv3_000105 CC(C)(C)OC(=O)Nc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E18 compound treatment 0.232 8.67E-4 0.12 0.233 0.00731 1.06 0.8315 0.7823 1334112 ChemDiv3_000106 Cc1ccc(NCn2c(=O)oc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E19 compound treatment 0.291 0.0599 8.27 0.289 0.0633 9.15 12.3149 0.9987 1464160 ChemDiv3_000107 OCCNC(=O)c1cc2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E20 compound treatment 0.218 -0.0131 -1.81 0.219 -0.00669 -0.97 -1.966 -0.9565 1484925 ChemDiv3_000108 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E21 compound treatment 0.609 0.378 52.2 0.614 0.388 56.09 76.5745 0.9994 3117594 ChemDiv3_000109 [O-][S+]1NN([S+]([O-])NN1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E22 compound treatment 0.251 0.0199 2.74 0.242 0.0163 2.36 3.6069 0.9971 1033254 ChemDiv3_000110 COc1cc(NCCCC(C)N)c2ncccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E23 mock treatment 0.23 -0.00113 -0.16 0.224 -0.00169 -0.24 -0.2831 -0.9771 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 E24 positive control 0.233 0.00187 0.26 0.227 0.00131 0.19 0.3164 0.9886 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F01 compound treatment 0.222 -0.00913 -1.26 0.222 -0.00369 -0.53 -1.2688 -0.9264 1915982 ChemDiv3_000111 O=C1NC(=O)/C(=C/c2ccccc2)/C(=O)N1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F02 compound treatment 0.282 0.0509 7.03 0.271 0.0453 6.55 9.5972 0.9994 1272580 ChemDiv3_000112 CC(=C)CN1c2ccccc2Sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F03 compound treatment 0.228 -0.00313 -0.43 0.224 -0.00169 -0.24 -0.4784 -0.9631 1220799 ChemDiv3_000113 Cc1ccc(Nc2ccc3noc4-c5ccccc5C(=O)c2c43)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F04 compound treatment 0.237 0.00587 0.81 0.236 0.0103 1.49 1.6264 0.9591 1191611 ChemDiv3_000114 O=c1oc2ccccc2c(Nc3ccccc3)c1CN4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F05 compound treatment 0.223 -0.00813 -1.12 0.214 -0.0117 -1.69 -1.9883 -0.9804 1052238 ChemDiv3_000115 COc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F06 compound treatment 0.226 -0.00513 -0.71 0.223 -0.00269 -0.39 -0.776 -0.9598 1363766 ChemDiv3_000116 Cc1cccc(c1)N(CC(=O)O)CC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F07 compound treatment 0.322 0.0909 12.55 0.349 0.123 17.81 21.4715 0.9853 1561715 ChemDiv3_000117 O=C(Nc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F08 compound treatment 0.238 0.00687 0.95 0.239 0.0133 1.92 2.0305 0.947 1160251 ChemDiv3_000118 CCCC1CCC(CC1)c2ccc(OC(=O)c3ccco3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F09 compound treatment 0.218 -0.0131 -1.81 0.22 -0.00569 -0.82 -1.8639 -0.9358 1185575 ChemDiv3_000119 Cc1cc(F)ccc1S(=O)(=O)NCC2CC3CCC2C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F10 compound treatment 0.218 -0.0131 -1.81 0.218 -0.00769 -1.11 -2.0682 -0.9722 1298807 ChemDiv3_000120 OCC(O)C1OC(Nc2ccc(Cl)cc2)C(O)C1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F11 compound treatment 0.215 -0.0161 -2.23 0.217 -0.00869 -1.25 -2.4634 -0.9631 1454827 ChemDiv3_000121 CC(C)(c1ccccc1)c2cc(CN3CCOCC3)c(O)c(CN4CCOCC4)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F12 compound treatment 0.241 0.00987 1.36 0.245 0.0193 2.79 2.9364 0.9458 1403981 ChemDiv3_000122 COc1ccc2oc(=O)c(cc2c1)c3cnc(C)s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F13 compound treatment 0.236 0.00487 0.67 0.23 0.00431 0.62 0.9159 0.9993 3117595 ChemDiv3_000123 O/N=C(\C(=O)c1ccccc1Cl)/n2cncn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F14 compound treatment 0.223 -0.00813 -1.12 0.22 -0.00569 -0.82 -1.3754 -0.9882 3117598 ChemDiv3_000124 CC1(C)COP(=S)(OC1)C(Nc2ccc(Cl)cc2)c3ccc(O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F15 compound treatment 0.224 -0.00713 -0.99 0.22 -0.00569 -0.82 -1.2778 -0.9959 1605115 ChemDiv3_000125 Oc1ccccc1c2nsnc2C(=O)N3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F16 compound treatment 0.262 0.0309 4.26 0.26 0.0343 4.96 6.5199 0.9972 1419832 ChemDiv3_000126 O=C(Oc1ccc(cc1)S(=O)(=O)c2ccc(OC(=O)c3cccs3)cc2)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F17 compound treatment 0.226 -0.00513 -0.71 0.223 -0.00269 -0.39 -0.776 -0.9598 1721700 ChemDiv3_000127 COc1cccc(c1)C2(CCCC2)c3ccc(O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F18 compound treatment 0.225 -0.00613 -0.85 0.227 0.00131 0.19 -0.4651 -0.5357 1321397 ChemDiv3_000128 Nc1ncn(CC(O)CO)c2nc(Br)nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F19 compound treatment 0.226 -0.00513 -0.71 0.222 -0.00369 -0.53 -0.8781 -0.99 3019915 ChemDiv3_000129 COc1ccc(cc1)C(=O)C[n+]2ccc3n(C)nnc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F20 compound treatment 0.221 -0.0101 -1.4 0.22 -0.00569 -0.82 -1.5708 -0.9677 1406847 ChemDiv3_000130 CCCC1CCC(CC1)c2ccc(OC(=O)c3cccs3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F21 compound treatment 0.218 -0.0131 -1.81 0.217 -0.00869 -1.25 -2.1703 -0.9838 1504493 ChemDiv3_000131 CC(=O)N1C(NC(=S)N)C(=O)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F22 compound treatment 0.221 -0.0101 -1.4 0.217 -0.00869 -1.25 -1.8772 -0.9985 1667131 ChemDiv3_000132 CCOc1ccc(OC(=O)c2cccnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F23 mock treatment 0.23 -0.00113 -0.16 0.222 -0.00369 -0.53 -0.4873 -0.8778 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 F24 positive control 0.233 0.00187 0.26 0.227 0.00131 0.19 0.3164 0.9886 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G01 compound treatment 0.222 -0.00913 -1.26 0.223 -0.00269 -0.39 -1.1667 -0.8838 1210291 ChemDiv3_000133 CN(C)CCOC(=O)c1ccc2[nH]c3CCSCc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G02 compound treatment 0.221 -0.0101 -1.4 0.22 -0.00569 -0.82 -1.5708 -0.9677 1432983 ChemDiv3_000134 O=C(CC1(CC2CC3CC(C2)C1)C3)N4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G03 compound treatment 0.222 -0.00913 -1.26 0.221 -0.00469 -0.68 -1.371 -0.9574 3019916 ChemDiv3_000135 CC(Cc1ccccc1)[n+]2cc(N)on2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G04 compound treatment 0.255 0.0239 3.3 0.249 0.0233 3.37 4.7126 0.9999 1091968 ChemDiv3_000136 Nc1ccc(Br)cc1C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G05 compound treatment 0.318 0.0869 12.0 0.299 0.0733 10.59 15.9738 0.9981 1446265 ChemDiv3_000137 CC(=O)Oc1ccc2ccc3ccc(OC(=O)C)c4ccc1c2c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G06 compound treatment 0.225 -0.00613 -0.85 0.224 -0.00169 -0.24 -0.7715 -0.875 3019918 ChemDiv3_000138 O/N=C/c1ccc[n+](CC(=O)NCc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G07 compound treatment 0.232 8.67E-4 0.12 0.231 0.00531 0.77 0.6273 0.8077 3117599 ChemDiv3_000139 CC1CCC/C(=C/c2ccc(Cl)cc2)/C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G08 compound treatment 0.246 0.0149 2.05 0.244 0.0183 2.65 3.3227 0.9922 1662647 ChemDiv3_000140 CCOC(=O)NC(=S)Nc1ccc(NC(=O)c2cc(Cl)ccc2O)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G09 compound treatment 0.22 -0.0111 -1.54 0.221 -0.00469 -0.68 -1.5664 -0.9321 1320817 ChemDiv3_000141 CCN(CC)C(=O)N1CCN(CCC#N)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G10 compound treatment 0.217 -0.0141 -1.95 0.221 -0.00469 -0.68 -1.8594 -0.8997 1913999 ChemDiv3_000142 CC(Cc1c[nH]c2ccccc12)NC(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G11 compound treatment 0.313 0.0819 11.31 0.303 0.0773 11.17 15.8939 1.0 3117600 ChemDiv3_000143 S=c1nc(oc2CCCCc21)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G12 compound treatment 0.224 -0.00713 -0.99 0.224 -0.00169 -0.24 -0.8692 -0.8562 3019921 ChemDiv3_000144 CC(C)(C)C(=O)C[n+]1ccc(cc1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G13 compound treatment 0.228 -0.00313 -0.43 0.222 -0.00369 -0.53 -0.6827 -0.9947 1032623 ChemDiv3_000145 O=C(N(Nc1ccccc1)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G14 compound treatment 0.22 -0.0111 -1.54 0.219 -0.00669 -0.97 -1.7706 -0.9749 3117601 ChemDiv3_000146 OC(=O)c1ccc(NC(=O)C[n+]2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G15 compound treatment 0.235 0.00387 0.53 0.238 0.0123 1.78 1.6353 0.8806 3117602 ChemDiv3_000147 CSc1ccc(Sc2ccc(SC)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G16 compound treatment 0.224 -0.00713 -0.99 0.219 -0.00669 -0.97 -1.3799 -1.0 1075919 ChemDiv3_000148 Clc1ccc(OCC(=O)NCCc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G17 compound treatment 0.27 0.0389 5.37 0.267 0.0413 5.97 8.0164 0.9986 1146554 ChemDiv3_000149 OCC1(C(=O)c2ccccc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G18 compound treatment 0.311 0.0799 11.03 0.298 0.0723 10.45 15.1879 0.9996 1723737 ChemDiv3_000150 NC(=S)c1cc2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G19 compound treatment 0.241 0.00987 1.36 0.234 0.00831 1.2 1.8129 0.998 1601550 ChemDiv3_000151 COc1ccc(C2C(=O)c3ccccc3C2=O)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G20 compound treatment 0.215 -0.0161 -2.23 0.218 -0.00769 -1.11 -2.3612 -0.9482 1302822 ChemDiv3_000152 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G21 compound treatment 0.256 0.0249 3.44 0.248 0.0223 3.22 4.7081 0.9995 3019795 ChemDiv3_000153 S=C1NN=C(C(N1)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G22 compound treatment 0.249 0.0179 2.47 0.246 0.0203 2.93 3.82 0.9963 1416806 ChemDiv3_000154 Nc1ccc(cc1)C(=O)Nc2ccc(cc2N)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G23 mock treatment 0.23 -0.00113 -0.16 0.228 0.00231 0.33 0.1255 0.3401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 G24 positive control 0.232 8.67E-4 0.12 0.225 -6.88E-4 -0.1 0.0144 0.0928 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H01 compound treatment 0.225 -0.00613 -0.85 0.226 3.12E-4 0.05 -0.5672 -0.6685 1123126 ChemDiv3_000155 C(CN1CCOCC1)Sc2nc3ccccc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H02 compound treatment 0.486 0.255 35.21 0.494 0.268 38.76 52.3023 0.9989 3019817 ChemDiv3_000156 CCOC(=O)c1c(C)c(C)sc1/N=C/c2ccc(cc2)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H03 compound treatment 0.245 0.0139 1.92 0.237 0.0113 1.63 2.51 0.9969 3117603 ChemDiv3_000157 CCOC(=O)c1c(C)c(C)sc1/N=C/c2ccccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H04 compound treatment 0.324 0.0929 12.83 0.321 0.0953 13.77 18.807 0.9994 3019818 ChemDiv3_000158 COc1ccc(cc1)N(C(=O)/C=C/c2ccc(OC)c(OC)c2)C3=CC4CCC(C3)N4C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H05 compound treatment 0.222 -0.00913 -1.26 0.219 -0.00669 -0.97 -1.5753 -0.9913 1020750 ChemDiv3_000159 NC(=O)c1ccc[n+](CC(=O)c2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H06 compound treatment 0.246 0.0149 2.05 0.255 0.0293 4.23 4.4462 0.9448 1221336 ChemDiv3_000160 Cc1ccc(OC(=O)c2ccccc2)c(c1)n3nc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H07 compound treatment 0.249 0.0179 2.47 0.259 0.0333 4.81 5.1478 0.9519 1171342 ChemDiv3_000161 COC(=O)NC(=S)Nc1ccc(Oc2ccc(Cl)cc2Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H08 compound treatment 0.254 0.0229 3.16 0.25 0.0243 3.51 4.717 0.9986 1054931 ChemDiv3_000162 O=C(Oc1ccc(cc1)c2ccccc2)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H09 compound treatment 0.221 -0.0101 -1.4 0.216 -0.00969 -1.4 -1.9794 -1.0 1080023 ChemDiv3_000163 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H10 compound treatment 0.293 0.0619 8.55 0.299 0.0733 10.59 13.5316 0.9944 1270809 ChemDiv3_000164 Cc1ccccc1C(=O)N2N=C(CC2c3nc4ccccc4[nH]3)c5ccc(Br)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H11 compound treatment 0.244 0.0129 1.78 0.242 0.0163 2.36 2.923 0.9903 1111851 ChemDiv3_000165 OCc1nc2cc3ccccc3cc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H12 compound treatment 0.226 -0.00513 -0.71 0.222 -0.00369 -0.53 -0.8781 -0.99 3117604 ChemDiv3_000166 O=C1N(C(=O)c2cc(ccc12)c3ncc(o3)c4ccccc4)c5ncn[nH]5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H13 compound treatment 0.333 0.102 14.07 0.333 0.107 15.5 20.9118 0.9988 3019820 ChemDiv3_000167 Oc1ccccc1/C=N/n2c3ccccc3c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H14 compound treatment 0.258 0.0269 3.71 0.256 0.0303 4.38 5.7206 0.9966 3117605 ChemDiv3_000168 C/N=C(\C)/c1c(O)c2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H15 compound treatment 0.236 0.00487 0.67 0.234 0.00831 1.2 1.3244 0.9624 1279829 ChemDiv3_000169 Oc1ccccc1C2CCCCC2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H16 compound treatment 0.228 -0.00313 -0.43 0.227 0.00131 0.19 -0.172 -0.364 1311336 ChemDiv3_000170 Nc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(N)c3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H17 compound treatment 0.274 0.0429 5.92 0.27 0.0443 6.4 8.7136 0.9992 1341633 ChemDiv3_000171 Cc1cc(C)c2ccc(NN)nc2c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H18 compound treatment 0.225 -0.00613 -0.85 0.224 -0.00169 -0.24 -0.7715 -0.875 3117606 ChemDiv3_000172 CC(=O)Nc1c(C)nn(c1O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H19 compound treatment 0.399 0.168 23.19 0.385 0.159 23.01 32.6704 1.0 3019822 ChemDiv3_000173 COc1ccc2nc(C)cc(S)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H20 compound treatment 0.222 -0.00913 -1.26 0.219 -0.00669 -0.97 -1.5753 -0.9913 1016095 ChemDiv3_000174 COC(=O)c1cccc(n1)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H21 compound treatment 0.253 0.0219 3.02 0.248 0.0223 3.22 4.4151 0.9995 1229822 ChemDiv3_000175 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2ccc(I)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H22 compound treatment 0.241 0.00987 1.36 0.24 0.0143 2.07 2.4257 0.9796 1484239 ChemDiv3_000176 CC(C)OC(=O)c1cccc(n1)C(=O)Nc2ccc(NC(=O)C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H23 mock treatment 0.229 -0.00213 -0.29 0.229 0.00331 0.48 0.1299 0.2312 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 H24 positive control 0.234 0.00287 0.4 0.225 -6.88E-4 -0.1 0.2098 0.5139 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I01 compound treatment 0.223 -0.00813 -1.12 0.224 -0.00169 -0.24 -0.9669 -0.8409 1528297 ChemDiv3_000177 CCN(CC)C(=O)COc1ccc(C)nc1CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I02 compound treatment 0.224 -0.00713 -0.99 0.225 -6.88E-4 -0.1 -0.7671 -0.7744 1726229 ChemDiv3_000178 O=C(NC1CCCCC1)NC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I03 compound treatment 0.228 -0.00313 -0.43 0.226 3.12E-4 0.05 -0.2742 -0.63 1695838 ChemDiv3_000179 OC(=O)c1ccc2C(=O)c3ccccc3S(=O)(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I04 compound treatment 0.269 0.0379 5.23 0.262 0.0363 5.25 7.408 1.0 1706757 ChemDiv3_000180 CCCN(CCC)C(=O)Cn1ccc(=N)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I05 compound treatment 0.223 -0.00813 -1.12 0.222 -0.00369 -0.53 -1.1712 -0.9418 3019863 ChemDiv3_000181 OC(=O)c1ccc(cc1)c2ccc(Br)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I06 compound treatment 0.24 0.00887 1.22 0.238 0.0123 1.78 2.1237 0.9834 3117607 ChemDiv3_000182 C[N+](C)(CCOc1ccccc1)Cc2ccccc2.OC(=O)c1cc2ccccc2c(Br)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I07 compound treatment 0.223 -0.00813 -1.12 0.225 -6.88E-4 -0.1 -0.8647 -0.7666 1103446 ChemDiv3_000183 OC(=O)C(Cc1ccccc1)NC=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I08 compound treatment 0.232 8.67E-4 0.12 0.229 0.00331 0.48 0.423 0.8576 3019864 ChemDiv3_000184 NC(=S)/N=C/1\CCCCC1=C2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I09 compound treatment 0.263 0.0319 4.4 0.258 0.0323 4.67 6.4133 0.9996 3117608 ChemDiv3_000185 Clc1ccc(cc1)S(=O)(=O)/N=C/2\SCCN2S(=O)(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I10 compound treatment 0.22 -0.0111 -1.54 0.221 -0.00469 -0.68 -1.5664 -0.9321 3019865 ChemDiv3_000186 NC(=O)c1ccc[n+](CC(=O)N(CC=C)CC=C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I11 compound treatment 0.219 -0.0121 -1.68 0.221 -0.00469 -0.68 -1.6641 -0.9205 1008424 ChemDiv3_000187 Nc1ccc(Sc2ccc(N)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I12 compound treatment 0.224 -0.00713 -0.99 0.222 -0.00369 -0.53 -1.0735 -0.9583 3117609 ChemDiv3_000188 CC(C)(C)OC(=O)C[n+]1ccc(cc1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I13 compound treatment 0.239 0.00787 1.09 0.236 0.0103 1.49 1.8218 0.988 1590292 ChemDiv3_000189 Cc1ccc(cc1)C(=O)Oc2cc(C)cc(OC(=O)c3ccc(C)cc3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I14 compound treatment 0.235 0.00387 0.53 0.235 0.00931 1.35 1.3289 0.9182 3019866 ChemDiv3_000190 Brc1ccc2[n+](C/C=C/c3ccccc3)cccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I15 compound treatment 0.224 -0.00713 -0.99 0.23 0.00431 0.62 -0.2564 -0.2199 2121292 ChemDiv3_000191 Clc1ccc(cc1Cl)S(=O)(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I16 compound treatment 0.22 -0.0111 -1.54 0.218 -0.00769 -1.11 -1.8728 -0.9872 1483300 ChemDiv3_000192 COc1ccc(Cl)c(NCCC(=O)O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I17 compound treatment 0.233 0.00187 0.26 0.225 -6.88E-4 -0.1 0.1121 0.4058 1243544 ChemDiv3_000193 CCOc1ccc(cc1OC)C2(CC(=O)Nc3ccccc3)C(=O)c4ccccc4C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I18 compound treatment 0.247 0.0159 2.19 0.239 0.0133 1.92 2.9097 0.9979 1632789 ChemDiv3_000194 O=C(Nc1cccc2ccccc12)c3cc4ccccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I19 compound treatment 0.243 0.0119 1.64 0.243 0.0173 2.5 2.9275 0.979 1020326 ChemDiv3_000195 CCOC(=O)C1=C(O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I20 compound treatment 0.223 -0.00813 -1.12 0.22 -0.00569 -0.82 -1.3754 -0.9882 1160580 ChemDiv3_000196 OC(=O)C(Cc1cnc[nH]1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I21 compound treatment 0.221 -0.0101 -1.4 0.217 -0.00869 -1.25 -1.8772 -0.9985 1223725 ChemDiv3_000197 OC(=O)CC1(CC2CC3C1)CC(CC(=O)O)(C2)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I22 compound treatment 0.227 -0.00413 -0.57 0.225 -6.88E-4 -0.1 -0.474 -0.8178 3019868 ChemDiv3_000198 OC(=O)c1ccc(C(=O)O)c(c1)c2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I23 mock treatment 0.232 8.67E-4 0.12 0.228 0.00231 0.33 0.3209 0.9042 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 I24 positive control 0.234 0.00287 0.4 0.223 -0.00269 -0.39 0.0055 0.01 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J01 compound treatment 0.237 0.00587 0.81 0.24 0.0143 2.07 2.035 0.9164 3117610 ChemDiv3_000199 N/N=C(\C(=O)O)/c1ccccc1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J02 compound treatment 0.255 0.0239 3.3 0.244 0.0183 2.65 4.2019 0.994 3019869 ChemDiv3_000200 O=C(C[n+]1ccc(C#N)cc1)c2ccc(NC(=O)c3ccccc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J03 compound treatment 0.404 0.173 23.88 0.383 0.157 22.72 32.9546 0.9997 3117612 ChemDiv3_000201 O=C(/C=C/c1c[nH]c2ccccc12)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J04 compound treatment 0.222 -0.00913 -1.26 0.223 -0.00269 -0.39 -1.1667 -0.8838 1170304 ChemDiv3_000202 OC(=O)CCNc1cc(Cl)ccc1Oc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J05 compound treatment 0.226 -0.00513 -0.71 0.221 -0.00469 -0.68 -0.9802 -0.9997 3019870 ChemDiv3_000203 O=C(C[n+]1cccc(NC(=O)c2ccccc2)c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J06 compound treatment 0.229 -0.00213 -0.29 0.226 3.12E-4 0.05 -0.1765 -0.5919 1618034 ChemDiv3_000204 COc1ccc(cc1)N2C(=O)C3CC=CC(C)C3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J07 compound treatment 0.227 -0.00413 -0.57 0.226 3.12E-4 0.05 -0.3719 -0.6492 3117613 ChemDiv3_000205 CCn1c(C)[n+](CC)c2cc(ccc12)S(=O)(=O)NC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J08 compound treatment 0.273 0.0419 5.78 0.275 0.0493 7.12 9.1266 0.9947 1082227 ChemDiv3_000206 C(CSc1nc2ccccc2[nH]1)Sc3nc4ccccc4[nH]3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J09 compound treatment 0.24 0.00887 1.22 0.23 0.00431 0.62 1.3066 0.9508 3019871 ChemDiv3_000207 Cc1ccc(cc1C)C(=O)c2ccc(C)c(C)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J10 compound treatment 0.245 0.0139 1.92 0.246 0.0203 2.93 3.4293 0.9787 1921766 ChemDiv3_000208 CC(/N=C/c1ccccc1O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J11 compound treatment 0.324 0.0929 12.83 0.325 0.0993 14.35 19.2155 0.9984 1340958 ChemDiv3_000209 CCN(CC)CCSc1nnc2c3ccccc3n(CC(=O)N)c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J12 compound treatment 0.295 0.0639 8.82 0.291 0.0653 9.43 12.9099 0.9994 1421356 ChemDiv3_000210 O=C(Nc1nc(cs1)c2ccccc2)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J13 compound treatment 0.254 0.0229 3.16 0.259 0.0333 4.81 5.6363 0.9792 3019898 ChemDiv3_000211 Oc1ccccc1/C=N/c2cccc(\N=C\c3ccccc3O)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J14 compound treatment 0.262 0.0309 4.26 0.262 0.0363 5.25 6.7242 0.9947 3117614 ChemDiv3_000212 Clc1ccc2[nH]c(=O)nc(c3ccccc3)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J15 compound treatment 0.269 0.0379 5.23 0.266 0.0403 5.82 7.8166 0.9986 1122932 ChemDiv3_000213 Oc1cc(cc(c1)C2CCCCC2)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J16 compound treatment 0.228 -0.00313 -0.43 0.224 -0.00169 -0.24 -0.4784 -0.9631 3117615 ChemDiv3_000214 CC(=O)NC1=NN(C(=O)C)C(C)(CS(=O)(=O)c2ccc(C)cc2)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J17 compound treatment 0.358 0.127 17.53 0.347 0.121 17.52 24.784 1.0 1730515 ChemDiv3_000215 CNc1ccc2cccc(Oc3ccc4cccc(O)c4n3)c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J18 compound treatment 0.226 -0.00513 -0.71 0.223 -0.00269 -0.39 -0.776 -0.9598 1591676 ChemDiv3_000216 Nc1cccc(NC(=O)CCC(=O)O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J19 compound treatment 0.23 -0.00113 -0.16 0.23 0.00431 0.62 0.3298 0.5134 3117616 ChemDiv3_000217 CC1(C)CC(CC(C)(C)N1)/N=C/c2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J20 compound treatment 0.227 -0.00413 -0.57 0.226 3.12E-4 0.05 -0.3719 -0.6492 1528923 ChemDiv3_000218 CC(C)OC(=O)c1cccc(n1)C(=O)OC(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J21 compound treatment 0.225 -0.00613 -0.85 0.222 -0.00369 -0.53 -0.9758 -0.975 1320476 ChemDiv3_000219 OC(=O)CC(N1C(=O)c2ccccc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J22 compound treatment 0.226 -0.00513 -0.71 0.22 -0.00569 -0.82 -1.0824 -0.9973 1009844 ChemDiv3_000220 Nc1cc(ccc1O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J23 mock treatment 0.232 8.67E-4 0.12 0.228 0.00231 0.33 0.3209 0.9042 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 J24 positive control 0.235 0.00387 0.53 0.228 0.00231 0.33 0.6139 0.9744 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K01 compound treatment 0.229 -0.00213 -0.29 0.229 0.00331 0.48 0.1299 0.2312 1273679 ChemDiv3_000221 CCN(CC)CCOc1ccc2nc(sc2c1)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K02 compound treatment 0.224 -0.00713 -0.99 0.222 -0.00369 -0.53 -1.0735 -0.9583 1202625 ChemDiv3_000222 OCCC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K03 compound treatment 0.227 -0.00413 -0.57 0.223 -0.00269 -0.39 -0.6783 -0.9823 1450413 ChemDiv3_000223 CS(=O)(=O)CS(=O)(=O)C1=C(C2CCN1CC2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K04 compound treatment 0.272 0.0409 5.65 0.274 0.0483 6.98 8.9267 0.9945 1353143 ChemDiv3_000224 CC(C)N(C(C)C)C(=O)Cn1ccc(=N)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K05 compound treatment 0.224 -0.00713 -0.99 0.222 -0.00369 -0.53 -1.0735 -0.9583 3117617 ChemDiv3_000225 CCCCc1ccc(CC(=O)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K06 compound treatment 0.264 0.0329 4.54 0.261 0.0353 5.1 6.8174 0.9983 3019901 ChemDiv3_000226 CC[n+]1cccc(c1)c2nc3ccccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K07 compound treatment 0.22 -0.0111 -1.54 0.23 0.00431 0.62 -0.6471 -0.39 1058991 ChemDiv3_000227 CCc1ccc(CC(=S)N2CCOCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K08 compound treatment 0.226 -0.00513 -0.71 0.23 0.00431 0.62 -0.061 -0.0646 1049850 ChemDiv3_000228 C(N1CCN(CC1)c2ccccc2)N3CCN(CC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K09 compound treatment 0.219 -0.0121 -1.68 0.219 -0.00669 -0.97 -1.8683 -0.9657 1529951 ChemDiv3_000229 COc1ccc2N(C)C(=O)C(C)(CC#N)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K10 compound treatment 0.222 -0.00913 -1.26 0.221 -0.00469 -0.68 -1.371 -0.9574 3117618 ChemDiv3_000230 NC(=O)c1cc[n+](CC(=O)N(CC=C)CC=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K11 compound treatment 0.221 -0.0101 -1.4 0.221 -0.00469 -0.68 -1.4687 -0.9444 1049796 ChemDiv3_000231 C[n+]1ccc(cc1)c2cc[n+](C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K12 compound treatment 0.225 -0.00613 -0.85 0.224 -0.00169 -0.24 -0.7715 -0.875 3117619 ChemDiv3_000232 O/N=C/c1ccc[n+](C/C=C/c2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K13 compound treatment 0.258 0.0269 3.71 0.258 0.0323 4.67 5.9249 0.9936 1377603 ChemDiv3_000233 Cc1cccc(NC(=O)c2cccc(c2)C(=O)Nc3cccc(C)c3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K14 compound treatment 0.305 0.0739 10.2 0.299 0.0733 10.59 14.7039 0.9998 3117620 ChemDiv3_000234 NC(=O)NC(=O)C[n+]1ccc(/C=N/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K15 compound treatment 0.226 -0.00513 -0.71 0.221 -0.00469 -0.68 -0.9802 -0.9997 1086380 ChemDiv3_000235 Brc1ccc(cc1)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K16 compound treatment 0.226 -0.00513 -0.71 0.226 3.12E-4 0.05 -0.4695 -0.6608 3117621 ChemDiv3_000236 OC(=O)CN(CCc1ccccc1)CC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K17 compound treatment 0.261 0.0299 4.13 0.262 0.0363 5.25 6.6265 0.9929 1677145 ChemDiv3_000237 O=C1C(C(C2C(=O)c3ccccc3C2=O)c4ccccc4)C(=O)c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K18 compound treatment 0.235 0.00387 0.53 0.232 0.00631 0.91 1.0225 0.9676 1190677 ChemDiv3_000238 CCN(CC)c1ccc2cc(C(=O)Nc3ccccc3)c(=N)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K19 compound treatment 0.258 0.0269 3.71 0.246 0.0203 2.93 4.6992 0.9932 3019902 ChemDiv3_000239 CCC(=O)c1ccc2cc(OC)ccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K20 compound treatment 0.223 -0.00813 -1.12 0.223 -0.00269 -0.39 -1.069 -0.8992 1231229 ChemDiv3_000240 CCCCC(N1C(=O)c2ccccc2C1=O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K21 compound treatment 0.225 -0.00613 -0.85 0.218 -0.00769 -1.11 -1.3843 -0.9911 1111942 ChemDiv3_000241 CN(C)CCC(=O)c1ccc(Br)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K22 compound treatment 0.239 0.00787 1.09 0.237 0.0113 1.63 1.9239 0.9804 3019922 ChemDiv3_000242 Cc1cc(NC(=O)c2ccc(N)cc2)c(N)cc1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K23 mock treatment 0.231 -1.33E-4 -0.02 0.228 0.00231 0.33 0.2232 0.6671 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 K24 positive control 0.231 -1.33E-4 -0.02 0.229 0.00331 0.48 0.3253 0.6794 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L01 compound treatment 0.237 0.00587 0.81 0.245 0.0193 2.79 2.5456 0.8763 3117622 ChemDiv3_000243 CC(=O)Nc1ccc(NC(=O)/C=N/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L02 compound treatment 0.219 -0.0121 -1.68 0.213 -0.0127 -1.83 -2.4812 -0.999 3117623 ChemDiv3_000244 O=C(C[n+]1cccc(c1)C(=O)Nc2ccccc2)c3ccc(cc3)N4C(=O)c5ccccc5C4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L03 compound treatment 0.226 -0.00513 -0.71 0.221 -0.00469 -0.68 -0.9802 -0.9997 3019923 ChemDiv3_000245 CC1(C)CC(CC(C)(C)N1)NC(=O)/C=C/C(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L04 compound treatment 0.237 0.00587 0.81 0.234 0.00831 1.2 1.4221 0.9817 1260714 ChemDiv3_000246 CC(C)(C)c1ccc(O)c(CN2CCN(CC2)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L05 compound treatment 0.225 -0.00613 -0.85 0.221 -0.00469 -0.68 -1.0779 -0.9938 3019924 ChemDiv3_000247 CC(C)N1C(=O)N(C(=CC1(C)C)C)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L06 compound treatment 0.24 0.00887 1.22 0.234 0.00831 1.2 1.7152 1.0 1635573 ChemDiv3_000248 COc1ccc(cc1CN2CCOCC2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L07 compound treatment 0.23 -0.00113 -0.16 0.225 -6.88E-4 -0.1 -0.1809 -0.9759 1417227 ChemDiv3_000249 C1CN(CCO1)c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L08 compound treatment 0.251 0.0199 2.74 0.255 0.0293 4.23 4.9347 0.978 3019925 ChemDiv3_000250 Brc1ccc(cc1)N(CN2C(=O)c3ccccc3C2=O)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L09 compound treatment 0.24 0.00887 1.22 0.235 0.00931 1.35 1.8173 0.9989 1196316 ChemDiv3_000251 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccnc3OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L10 compound treatment 0.287 0.0559 7.72 0.291 0.0653 9.43 12.1284 0.995 1401655 ChemDiv3_000252 CCSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L11 compound treatment 0.22 -0.0111 -1.54 0.219 -0.00669 -0.97 -1.7706 -0.9749 1010418 ChemDiv3_000253 Oc1ccc(cc1)S(=O)(=O)c2ccc(O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L12 compound treatment 0.223 -0.00813 -1.12 0.221 -0.00469 -0.68 -1.2733 -0.9706 1538510 ChemDiv3_000254 CCOC(=O)n1c(=O)oc2cc(Cl)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L13 compound treatment 0.235 0.00387 0.53 0.235 0.00931 1.35 1.3289 0.9182 1642025 ChemDiv3_000255 CCOC(=O)Nc1cc(=O)c2ccccc2o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L14 compound treatment 0.28 0.0489 6.75 0.251 0.0253 3.66 7.359 0.9585 1641183 ChemDiv3_000256 O=C(COC(=O)c1cc2ccccc2oc1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L15 compound treatment 0.236 0.00487 0.67 0.222 -0.00369 -0.53 0.0988 0.1152 3019926 ChemDiv3_000257 O/N=C(\c1ccccc1)/C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L16 compound treatment 0.367 0.136 18.77 0.363 0.137 19.83 27.2974 0.9996 3117624 ChemDiv3_000258 CC[n+]1c(/C=C\2/CC(C)(C)CC(=C2)C)oc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L17 compound treatment 0.263 0.0319 4.4 0.272 0.0463 6.69 7.8433 0.9794 1920076 ChemDiv3_000259 Cc1cc(C)c2ccc(/C=N/O)nc2c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L18 compound treatment 0.372 0.141 19.46 0.361 0.135 19.55 27.5815 1.0 3117625 ChemDiv3_000260 CC[n+]1c(/C=C/2\CC(C)CC(=C2)C)sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L19 compound treatment 0.227 -0.00413 -0.57 0.221 -0.00469 -0.68 -0.8825 -0.9964 1315100 ChemDiv3_000261 CSc1nc2ccccc2n1CN(C)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L20 compound treatment 0.227 -0.00413 -0.57 0.222 -0.00369 -0.53 -0.7804 -0.9994 1305784 ChemDiv3_000262 COC(=O)c1cccc(n1)C(=O)Oc2ccc(OC(=O)c3cccc(n3)C(=O)OC)c(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L21 compound treatment 0.249 0.0179 2.47 0.243 0.0173 2.5 3.5136 1.0 1433025 ChemDiv3_000263 Cc1cc(cc(C)c1N)C2(CCCCC2)c3cc(C)c(N)c(C)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L22 compound treatment 0.425 0.194 26.78 0.418 0.192 27.78 38.5809 0.9998 1464584 ChemDiv3_000264 CN(C)c1ccc(cc1)C(O)C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L23 mock treatment 0.231 -1.33E-4 -0.02 0.228 0.00231 0.33 0.2232 0.6671 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 L24 positive control 0.23 -0.00113 -0.16 0.225 -6.88E-4 -0.1 -0.1809 -0.9759 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M01 compound treatment 0.23 -0.00113 -0.16 0.229 0.00331 0.48 0.2276 0.4521 1660133 ChemDiv3_000265 CC1=CC(=O)OC1Cc2ccc3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M02 compound treatment 0.256 0.0249 3.44 0.25 0.0243 3.51 4.9124 0.9999 1710588 ChemDiv3_000266 CC(=O)Nc1nc(cs1)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M03 compound treatment 0.417 0.186 25.68 0.421 0.195 28.21 38.1058 0.9989 3117626 ChemDiv3_000267 C/N=C\1/S/C(=C\c2cn(CC(=O)O)c3ccccc23)/C(=O)N1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M04 compound treatment 0.226 -0.00513 -0.71 0.224 -0.00169 -0.24 -0.6738 -0.8986 3019928 ChemDiv3_000268 CC(C)(C)NC(=O)C[n+]1cccc(/C=N/O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M05 compound treatment 0.227 -0.00413 -0.57 0.222 -0.00369 -0.53 -0.7804 -0.9994 3117629 ChemDiv3_000269 CC(=O)OC1CCC(CC1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M06 compound treatment 0.229 -0.00213 -0.29 0.225 -6.88E-4 -0.1 -0.2786 -0.8959 3019929 ChemDiv3_000270 CC(=O)Nc1sc2CCCCc2c1SC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M07 compound treatment 0.224 -0.00713 -0.99 0.224 -0.00169 -0.24 -0.8692 -0.8562 3117630 ChemDiv3_000271 CCC1(CC)C(=[N+](C)c2ccccc21)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M08 compound treatment 0.226 -0.00513 -0.71 0.23 0.00431 0.62 -0.061 -0.0646 1692026 ChemDiv3_000272 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccccc2C(=O)NC3CC(C)(C)NC(C)(C)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M09 compound treatment 0.222 -0.00913 -1.26 0.223 -0.00269 -0.39 -1.1667 -0.8838 3019876 ChemDiv3_000273 CC[n+]1c(C)sc(c1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M10 compound treatment 0.223 -0.00813 -1.12 0.219 -0.00669 -0.97 -1.4776 -0.9972 3117631 ChemDiv3_000274 NC(=O)c1ccc[n+](CC(=O)N2CCCCC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M11 compound treatment 0.222 -0.00913 -1.26 0.22 -0.00569 -0.82 -1.4731 -0.9784 1141301 ChemDiv3_000275 COC(=O)Nc1ccc(cc1)S(=O)(=O)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M12 compound treatment 0.265 0.0339 4.68 0.259 0.0333 4.81 6.7108 0.9999 3117632 ChemDiv3_000276 O/N=C/c1cc[n+](CCC(=O)NCc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M13 compound treatment 0.258 0.0269 3.71 0.27 0.0443 6.4 7.1505 0.9664 3019878 ChemDiv3_000277 Cc1cccc(NC(=O)/C=C/c2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M14 compound treatment 0.221 -0.0101 -1.4 0.222 -0.00369 -0.53 -1.3665 -0.9123 3117633 ChemDiv3_000278 OC(=O)c1ccccc1NC(=O)C[n+]2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M15 compound treatment 0.223 -0.00813 -1.12 0.218 -0.00769 -1.11 -1.5797 -1.0 1048436 ChemDiv3_000279 O=C(Nc1ccccc1)C2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M16 compound treatment 0.39 0.159 21.95 0.388 0.162 23.45 32.0977 0.9995 1410422 ChemDiv3_000280 CCNc1c(N)c(=O)oc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M17 compound treatment 0.226 -0.00513 -0.71 0.226 3.12E-4 0.05 -0.4695 -0.6608 3019903 ChemDiv3_000281 Nc1nonc1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M18 compound treatment 0.248 0.0169 2.33 0.237 0.0113 1.63 2.8031 0.9849 3019904 ChemDiv3_000282 CC(C)C1=CCC(C)/C(=C\c2ccc(Cl)cc2)/C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M19 compound treatment 0.232 8.67E-4 0.12 0.225 -6.88E-4 -0.1 0.0144 0.0928 1010017 ChemDiv3_000283 O=C1C=CC(=O)N1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M20 compound treatment 0.235 0.00387 0.53 0.229 0.00331 0.48 0.7161 0.9985 1922526 ChemDiv3_000284 Brc1ccccc1c2nc3ccccc3c4nc5ccccc5n24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M21 compound treatment 0.266 0.0349 4.82 0.264 0.0383 5.53 7.3192 0.9976 1409537 ChemDiv3_000285 Nc1ccc(cc1)C(=O)CC(=O)Nc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M22 compound treatment 0.275 0.0439 6.06 0.274 0.0483 6.98 9.2198 0.9975 1104285 ChemDiv3_000286 OC(=O)c1cc2ccc3cccc4ccc(c1)c2c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M23 mock treatment 0.233 0.00187 0.26 0.228 0.00231 0.33 0.4185 0.9918 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 M24 positive control 0.228 -0.00313 -0.43 0.227 0.00131 0.19 -0.172 -0.364 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N01 compound treatment 0.235 0.00387 0.53 0.241 0.0153 2.21 1.9417 0.8533 3019905 ChemDiv3_000287 C/C(=C/C(=O)O)/C=C/c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N02 compound treatment 0.236 0.00487 0.67 0.237 0.0113 1.63 1.6309 0.923 1113098 ChemDiv3_000288 O=C(Oc1ccccc1OC(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N03 compound treatment 0.222 -0.00913 -1.26 0.219 -0.00669 -0.97 -1.5753 -0.9913 1455237 ChemDiv3_000289 S=C1NCN(CN1)C2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N04 compound treatment 0.231 -1.33E-4 -0.02 0.23 0.00431 0.62 0.4274 0.6859 1652365 ChemDiv3_000290 CC(C)c1cc(CN2CCN(CC2)c3ccccc3)c(O)c(CN4CCN(CC4)c5ccccc5)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N05 compound treatment 0.239 0.00787 1.09 0.238 0.0123 1.78 2.0261 0.9721 3019907 ChemDiv3_000291 CN(C)C/C(=N/O)/C(=O)Nc1ccc(C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N06 compound treatment 0.224 -0.00713 -0.99 0.222 -0.00369 -0.53 -1.0735 -0.9583 1498499 ChemDiv3_000292 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)nc(OC)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N07 compound treatment 0.22 -0.0111 -1.54 0.222 -0.00369 -0.53 -1.4642 -0.8996 1034347 ChemDiv3_000293 N#CCCn1nnc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N08 compound treatment 0.217 -0.0141 -1.95 0.224 -0.00169 -0.24 -1.553 -0.7893 3117634 ChemDiv3_000294 CC(=O)N(CN1C(=O)c2ccccc2C1=O)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N09 compound treatment 0.217 -0.0141 -1.95 0.224 -0.00169 -0.24 -1.553 -0.7893 1051930 ChemDiv3_000295 C(c1ccccc1)n2ccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N10 compound treatment 0.313 0.0819 11.31 0.308 0.0823 11.89 16.4046 0.9997 1022496 ChemDiv3_000296 OC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N11 compound treatment 0.217 -0.0141 -1.95 0.213 -0.0127 -1.83 -2.6765 -0.9995 1579194 ChemDiv3_000297 CN(C)C(=O)c1ccc(Oc2ccc(cc2)C(=O)N(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N12 compound treatment 0.261 0.0299 4.13 0.255 0.0293 4.23 5.9115 0.9999 1676465 ChemDiv3_000298 Clc1ccc(cc1)C(=O)n2c(=O)oc3cc(Cl)ccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N13 compound treatment 0.25 0.0189 2.61 0.245 0.0193 2.79 3.8156 0.9994 1542255 ChemDiv3_000299 CCOC(=O)c1c(O)cc(C)cc1Nc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N14 compound treatment 0.18 -0.0511 -7.06 0.181 -0.0447 -6.45 -9.5594 -0.999 3117635 ChemDiv3_000300 O=C(C[n+]1ccccc1)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N15 compound treatment 0.239 0.00787 1.09 0.238 0.0123 1.78 2.0261 0.9721 1382153 ChemDiv3_000301 O=C1N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N16 compound treatment 0.227 -0.00413 -0.57 0.241 0.0153 2.21 1.1602 0.5079 1667966 ChemDiv3_000302 O=C(Nc1ccc(cc1)c2nc3cc(NC(=O)C4CCCCC4)ccc3o2)C5CCCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N17 compound treatment 0.293 0.0619 8.55 0.288 0.0623 9.0 12.4081 0.9997 3019932 ChemDiv3_000303 COC(=O)c1cc2cc(Br)ccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N18 compound treatment 0.222 -0.00913 -1.26 0.225 -6.88E-4 -0.1 -0.9624 -0.7604 1508788 ChemDiv3_000304 CC(=O)Nc1ccc2oc3ccccc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N19 compound treatment 0.225 -0.00613 -0.85 0.219 -0.00669 -0.97 -1.2822 -0.9979 3019933 ChemDiv3_000305 NC(=O)CSc1nc2ccccc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N20 compound treatment 0.224 -0.00713 -0.99 0.223 -0.00269 -0.39 -0.9713 -0.9171 1682374 ChemDiv3_000306 COC(=O)c1cccc(n1)C(=O)Nc2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N21 compound treatment 0.232 8.67E-4 0.12 0.225 -6.88E-4 -0.1 0.0144 0.0928 1467868 ChemDiv3_000307 Cc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N22 compound treatment 0.22 -0.0111 -1.54 0.217 -0.00869 -1.25 -1.9749 -0.9949 3019936 ChemDiv3_000308 O=C/1OC(=N\C1=C/c2ccco2)c3ccc(cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N23 mock treatment 0.231 -1.33E-4 -0.02 0.226 3.12E-4 0.05 0.0189 0.3875 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 N24 positive control 0.229 -0.00213 -0.29 0.224 -0.00169 -0.24 -0.3808 -0.9955 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O01 compound treatment 0.269 0.0379 5.23 0.282 0.0563 8.13 9.4508 0.9772 3117636 ChemDiv3_000309 NNc1nc(cc(n1)c2ccccc2O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O02 compound treatment 0.231 -1.33E-4 -0.02 0.23 0.00431 0.62 0.4274 0.6859 3019937 ChemDiv3_000310 CCCc1[nH]c(Br)nc1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O03 compound treatment 0.228 -0.00313 -0.43 0.22 -0.00569 -0.82 -0.887 -0.9552 1573334 ChemDiv3_000311 COc1nsnc1N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O04 compound treatment 0.227 -0.00413 -0.57 0.219 -0.00669 -0.97 -1.0868 -0.9685 3117637 ChemDiv3_000312 CN(C)C(=O)C[n+]1cccc(/C=N/O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O05 compound treatment 0.247 0.0159 2.19 0.241 0.0153 2.21 3.114 1.0 1280359 ChemDiv3_000313 CCCCC1CCC(CC1)c2ccc(cc2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O06 compound treatment 0.305 0.0739 10.2 0.299 0.0733 10.59 14.7039 0.9998 3019939 ChemDiv3_000314 C[n+]1ccccc1c2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O07 compound treatment 0.229 -0.00213 -0.29 0.222 -0.00369 -0.53 -0.585 -0.9611 1372721 ChemDiv3_000315 CCCCC1CCC(CC1)C(=O)Oc2ccc(OCC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O08 compound treatment 0.262 0.0309 4.26 0.26 0.0343 4.96 6.5199 0.9972 1559693 ChemDiv3_000316 CCOC(=O)c1[nH]c2ccc(OCC)cc2c1CCCN3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O09 compound treatment 0.221 -0.0101 -1.4 0.219 -0.00669 -0.97 -1.673 -0.9836 1672292 ChemDiv3_000317 COC(=O)c1ccc2n(CCO)c(C)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O10 compound treatment 0.218 -0.0131 -1.81 0.214 -0.0117 -1.69 -2.4767 -0.9994 3117638 ChemDiv3_000318 CC(C)(C)CC[n+]1ccc(cc1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O11 compound treatment 0.218 -0.0131 -1.81 0.216 -0.00969 -1.4 -2.2724 -0.9918 3019783 ChemDiv3_000319 CN1C(N(C)c2ccccc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O12 compound treatment 0.247 0.0159 2.19 0.241 0.0153 2.21 3.114 1.0 3019784 ChemDiv3_000320 CC(C)(C)CC[n+]1ccc(/C=N/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O13 compound treatment 0.245 0.0139 1.92 0.249 0.0233 3.37 3.7357 0.9643 1564111 ChemDiv3_000321 Cc1ccc(cc1)C(=O)c2ccc(Oc3ccccc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O14 compound treatment 0.345 0.114 15.73 0.346 0.12 17.38 23.4119 0.9988 1011033 ChemDiv3_000322 Cc1nc(N)c(nc1C)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O15 compound treatment 0.273 0.0419 5.78 0.276 0.0503 7.27 9.2287 0.9936 1628748 ChemDiv3_000323 CN(CC(=O)C1=C(C(=O)c2ccccc2C1=O)c3ccc(Br)cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O16 compound treatment 0.346 0.115 15.87 0.35 0.124 17.96 23.9181 0.9981 1540210 ChemDiv3_000324 Nc1c(N2CCOCC2)c3ccccc3oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O17 compound treatment 0.237 0.00587 0.81 0.237 0.0113 1.63 1.7285 0.9477 1072203 ChemDiv3_000325 CCCn1c2ccccc2c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O18 compound treatment 0.252 0.0209 2.88 0.259 0.0333 4.81 5.4409 0.97 3019785 ChemDiv3_000326 COc1ccc(/C=C/2\C(C)CC=C(C(C)C)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O19 compound treatment 0.233 0.00187 0.26 0.231 0.00531 0.77 0.725 0.8955 1084080 ChemDiv3_000327 CC[n+]1ccc(C)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O20 compound treatment 0.22 -0.0111 -1.54 0.218 -0.00769 -1.11 -1.8728 -0.9872 1594899 ChemDiv3_000328 COC(=O)CNC(=O)c1cc(OC)c(OC)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O21 compound treatment 0.222 -0.00913 -1.26 0.216 -0.00969 -1.4 -1.8817 -0.9987 1181132 ChemDiv3_000329 O=C(NCC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O22 compound treatment 0.221 -0.0101 -1.4 0.218 -0.00769 -1.11 -1.7751 -0.9934 1124218 ChemDiv3_000330 CCc1nc(C)ccc1OCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O23 mock treatment 0.231 -1.33E-4 -0.02 0.224 -0.00169 -0.24 -0.1854 -0.7584 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 O24 positive control 0.226 -0.00513 -0.71 0.22 -0.00569 -0.82 -1.0824 -0.9973 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P01 compound treatment 0.223 -0.00813 -1.12 0.226 3.12E-4 0.05 -0.7626 -0.6782 1003174 ChemDiv3_000331 CC(O)c1ccc(Oc2ccc(cc2)C(C)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P02 compound treatment 0.691 0.46 63.53 0.69 0.464 67.07 92.3474 0.9996 3019787 ChemDiv3_000332 CN(C)c1ccc(/C=N/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P03 compound treatment 0.222 -0.00913 -1.26 0.223 -0.00269 -0.39 -1.1667 -0.8838 1340347 ChemDiv3_000333 CC(C)(C)c1cc(CN2CCN(CCC#N)CC2)cc(c1O)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P04 compound treatment 0.224 -0.00713 -0.99 0.218 -0.00769 -1.11 -1.482 -0.9982 3019803 ChemDiv3_000334 COc1cccc2s/c(=N/C(=O)CC3(CC4CC5CC(C4)C3)C5)/n(C)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P05 compound treatment 0.224 -0.00713 -0.99 0.22 -0.00569 -0.82 -1.2778 -0.9959 1922875 ChemDiv3_000335 CCN(CC)C(=O)C1(CC2CC3C1)CC(C2)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P06 compound treatment 0.27 0.0389 5.37 0.268 0.0423 6.11 8.1185 0.9979 3117639 ChemDiv3_000336 O/N=C/c1cccc[n+]1CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P07 compound treatment 0.224 -0.00713 -0.99 0.224 -0.00169 -0.24 -0.8692 -0.8562 1035295 ChemDiv3_000337 CC(C)(C)N1C(=O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P08 compound treatment 0.224 -0.00713 -0.99 0.224 -0.00169 -0.24 -0.8692 -0.8562 1005478 ChemDiv3_000338 Nc1ccc(Oc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P09 compound treatment 0.224 -0.00713 -0.99 0.218 -0.00769 -1.11 -1.482 -0.9982 1734538 ChemDiv3_000339 OC(=O)CCNC(=O)c1ccco1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P10 compound treatment 0.246 0.0149 2.05 0.25 0.0243 3.51 3.9355 0.9674 3117642 ChemDiv3_000340 CN(C)c1ccc(/C=C/2\CCC/C(=C\c3ccccc3)/C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P11 compound treatment 0.222 -0.00913 -1.26 0.223 -0.00269 -0.39 -1.1667 -0.8838 1511725 ChemDiv3_000341 COC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P12 compound treatment 0.221 -0.0101 -1.4 0.222 -0.00369 -0.53 -1.3665 -0.9123 1287341 ChemDiv3_000342 O=S(=O)(N1CCOCC1)c2cccc(c2)S(=O)(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P13 compound treatment 0.23 -0.00113 -0.16 0.222 -0.00369 -0.53 -0.4873 -0.8778 1166133 ChemDiv3_000343 CN(C)CCOC(=O)c1ccc2n(CCN(C)C)c(C)c(C)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P14 compound treatment 0.266 0.0349 4.82 0.263 0.0373 5.39 7.2171 0.9984 1920545 ChemDiv3_000344 O=c1cc([nH]c(=S)[nH]1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P15 compound treatment 0.226 -0.00513 -0.71 0.224 -0.00169 -0.24 -0.6738 -0.8986 3117643 ChemDiv3_000345 Oc1ccc(Br)cc1/C=N\CC2(CC3CC4CC(C3)CC2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P16 compound treatment 0.224 -0.00713 -0.99 0.223 -0.00269 -0.39 -0.9713 -0.9171 1350693 ChemDiv3_000346 Nc1ccc(CCc2nc3ccccc3[nH]2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P17 compound treatment 0.224 -0.00713 -0.99 0.218 -0.00769 -1.11 -1.482 -0.9982 1509469 ChemDiv3_000347 CCN(CC)C(=O)c1cc(nc2ccccc12)c3cc(C(=O)N(CC)CC)c4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P18 compound treatment 0.216 -0.0151 -2.09 0.222 -0.00369 -0.53 -1.855 -0.8598 3019852 ChemDiv3_000348 O/N=C(\Cn1cncn1)/c2ccc(Cl)cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P19 compound treatment 0.22 -0.0111 -1.54 0.22 -0.00569 -0.82 -1.6685 -0.9569 1127886 ChemDiv3_000349 C(Cc1nc2ccccc2o1)Cc3nc4ccccc4o3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P20 compound treatment 0.237 0.00587 0.81 0.251 0.0253 3.66 3.1585 0.8434 1524725 ChemDiv3_000350 COC(=O)c1cccc(n1)C(=O)Nc2cnc3ccccc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P21 compound treatment 0.219 -0.0121 -1.68 0.219 -0.00669 -0.97 -1.8683 -0.9657 1740437 ChemDiv3_000351 OC(CNCc1ccccc1)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P22 compound treatment 0.218 -0.0131 -1.81 0.219 -0.00669 -0.97 -1.966 -0.9565 3019853 ChemDiv3_000352 Brc1ccc(cc1)S(=O)(=O)/N=C(\Oc2ccccc2)/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P23 mock treatment 0.231 -1.33E-4 -0.02 0.226 3.12E-4 0.05 0.0189 0.3875 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2001 P24 positive control 0.233 0.00187 0.26 0.224 -0.00169 -0.24 0.01 0.0282 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A01 compound treatment 0.249 0.0182 2.51 0.249 0.0228 3.3 4.1079 0.9911 1487428 ChemDiv3_000705 CCOC(=O)C1=C(CC)NC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A02 compound treatment 0.26 0.0292 4.03 0.267 0.0408 5.9 7.021 0.9829 1295860 ChemDiv3_000706 Ic1ccc(NC(=O)COc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A03 compound treatment 0.222 -0.0088 -1.22 0.214 -0.0122 -1.76 -2.1045 -0.9837 1077646 ChemDiv3_000707 Clc1ccc2Sc3ccccc3N(CCC#N)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A04 compound treatment 0.215 -0.0158 -2.18 0.222 -0.00419 -0.6 -1.9712 -0.8703 3117740 ChemDiv3_000708 FC(F)(F)Oc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A05 compound treatment 0.213 -0.0178 -2.46 0.212 -0.0142 -2.05 -3.1879 -0.9959 3020717 ChemDiv3_000709 NC(=S)N1C(CCN1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A06 compound treatment 0.215 -0.0158 -2.18 0.212 -0.0142 -2.05 -2.9926 -0.9995 1443291 ChemDiv3_000710 OCCc1ccc(s1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A07 compound treatment 0.234 0.0032 0.44 0.218 -0.00819 -1.18 -0.5237 -0.4148 3117741 ChemDiv3_000711 CCN(N(CC)S(=O)(=O)c1ccc(C)cc1)C2=NS(=O)(=O)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A08 compound treatment 0.232 0.0012 0.17 0.237 0.0108 1.56 1.2216 0.7778 3020718 ChemDiv3_000712 COc1ccccc1/N=C/c2ccsc2S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A09 compound treatment 0.21 -0.0208 -2.87 0.212 -0.0142 -2.05 -3.481 -0.9863 1233664 ChemDiv3_000713 O=C(CCN1C(=O)c2ccccc2C1=O)NCc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A10 compound treatment 0.209 -0.0218 -3.01 0.207 -0.0192 -2.77 -4.0894 -0.9991 1914325 ChemDiv3_000714 NC(=N)SCCS(=O)(=O)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A11 compound treatment 0.212 -0.0188 -2.6 0.206 -0.0202 -2.92 -3.8984 -0.9983 1506625 ChemDiv3_000715 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A12 compound treatment 0.216 -0.0148 -2.04 0.216 -0.0102 -1.47 -2.4863 -0.987 1069326 ChemDiv3_000716 FC(F)(F)c1ccccc1NC(=O)c2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A13 compound treatment 0.213 -0.0178 -2.46 0.206 -0.0202 -2.92 -3.8008 -0.9964 1446136 ChemDiv3_000717 COc1ccc(NC(=O)C2CSC(C)(C)N2C=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A14 compound treatment 0.316 0.0852 11.77 0.344 0.118 17.02 20.3562 0.9838 3020719 ChemDiv3_000718 COc1ccc(/C=N/c2nc3ccccc3n2Cc4ccc(Cl)cc4)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A15 compound treatment 0.247 0.0162 2.24 0.255 0.0288 4.16 4.5254 0.9577 1718021 ChemDiv3_000719 COC(=O)c1cc(Cl)c(NC(=S)NC(=O)C(C)(C)C)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A16 compound treatment 0.238 0.0072 0.99 0.238 0.0118 1.71 1.9099 0.967 3117742 ChemDiv3_000720 CN(C)c1ccc(/C=N/c2nc3ccccc3n2Cc4ccc(C)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A17 compound treatment 0.208 -0.0228 -3.15 0.202 -0.0242 -3.49 -4.6978 -0.9987 1339224 ChemDiv3_000721 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A18 compound treatment 0.209 -0.0218 -3.01 0.211 -0.0152 -2.19 -3.6808 -0.9879 1054488 ChemDiv3_000722 Cc1cc(C)n(n1)S(=O)(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A19 compound treatment 0.217 -0.0138 -1.91 0.212 -0.0142 -2.05 -2.7972 -0.9993 1779183 ChemDiv3_000723 CC(C)COC(=O)CNc1n[nH]c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A20 compound treatment 0.257 0.0262 3.62 0.255 0.0288 4.16 5.5023 0.9976 3117743 ChemDiv3_000724 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(I)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A21 compound treatment 0.207 -0.0238 -3.29 0.208 -0.0182 -2.63 -4.1826 -0.9938 1646638 ChemDiv3_000725 COC(=O)C(Cc1ccc(O)cc1)NC(=O)c2ccccc2OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A22 compound treatment 0.213 -0.0178 -2.46 0.211 -0.0152 -2.19 -3.2901 -0.9984 1624682 ChemDiv3_000726 COC(=O)c1ccccc1NC(=O)CCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A23 mock treatment 0.218 -0.0128 -1.77 0.217 -0.00919 -1.33 -2.1888 -0.99 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 A24 positive control 0.215 -0.0158 -2.18 0.21 -0.0162 -2.34 -3.1968 -0.9994 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B01 compound treatment 0.286 0.0552 7.63 0.283 0.0568 8.21 11.1951 0.9993 1725673 ChemDiv3_000727 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B02 compound treatment 0.245 0.0142 1.96 0.235 0.00881 1.27 2.2873 0.9781 3117744 ChemDiv3_000728 CN1C(=O)/C(=C\2/SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B03 compound treatment 0.227 -0.0038 -0.52 0.224 -0.00219 -0.32 -0.5946 -0.9705 3020720 ChemDiv3_000729 Cc1cccc(c1)C(=O)Oc2ccc(C)c(C)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B04 compound treatment 0.275 0.0442 6.11 0.259 0.0328 4.74 7.6692 0.9922 1254173 ChemDiv3_000730 Cc1ccccc1OCCn2c(SCc3nc4ccccc4[nH]3)nc5ccccc25 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B05 compound treatment 0.227 -0.0038 -0.52 0.221 -0.00519 -0.75 -0.9011 -0.9849 3020816 ChemDiv3_000731 C1CCC2CC(OCC2C1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B06 compound treatment 0.275 0.0442 6.11 0.279 0.0528 7.63 9.712 0.9939 3117745 ChemDiv3_000732 Cc1ccc(cc1)S(=O)(=O)/N=C(/NC(=S)Nc2ccccc2)\c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B07 compound treatment 0.23 -8.0E-4 -0.11 0.222 -0.00419 -0.6 -0.5059 -0.8227 3020817 ChemDiv3_000733 CCN(CC)C(=O)CSc1nnc(o1)c2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B08 compound treatment 0.236 0.0052 0.72 0.232 0.00581 0.84 1.1017 0.997 3117746 ChemDiv3_000734 CC(=O)NC(=O)c/1cc2c(ccc3ccccc32)o\c1=N/c4ccc(C)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B09 compound treatment 0.279 0.0482 6.66 0.293 0.0668 9.65 11.5327 0.9836 1423328 ChemDiv3_000735 OC(CNCc1ccccc1)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B10 compound treatment 0.233 0.0022 0.3 0.23 0.00381 0.55 0.6043 0.9608 1240251 ChemDiv3_000736 Cc1c(Cl)cccc1NC(=O)c2cccnc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B11 compound treatment 0.239 0.0082 1.13 0.24 0.0138 2.0 2.2118 0.964 3020818 ChemDiv3_000737 CCOc1ccc-2c(c1)C(=O)c3cc(OCC)ccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B12 compound treatment 0.301 0.0702 9.7 0.295 0.0688 9.94 13.8861 0.9999 1727003 ChemDiv3_000738 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc3sc(SC)nc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B13 compound treatment 0.244 0.0132 1.82 0.246 0.0198 2.86 3.3131 0.9763 1740255 ChemDiv3_000739 Cc1ccc(cc1)S(=O)(=O)N2CCN(C2c3ccccc3)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B14 compound treatment 0.304 0.0732 10.11 0.292 0.0658 9.51 13.8727 0.9995 3020819 ChemDiv3_000740 CC1(C)CC(=S)C=C(C1)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B15 compound treatment 0.264 0.0332 4.59 0.259 0.0328 4.74 6.5946 0.9999 1741101 ChemDiv3_000741 Clc1cc2sc(=O)oc2cc1OC(=O)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B16 compound treatment 0.295 0.0642 8.87 0.273 0.0468 6.76 11.0529 0.991 3117538 ChemDiv3_000742 COc1ccc(OC)c(/N=C/c2cc(I)cc(C)c2O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B17 compound treatment 0.242 0.0112 1.55 0.243 0.0168 2.43 2.8113 0.9763 3117539 ChemDiv3_000743 CCOc1ccc(cc1)N2C(=O)S/C(=C/3\C(=O)Nc4ccccc34)/C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B18 compound treatment 0.308 0.0772 10.67 0.297 0.0708 10.23 14.7742 0.9998 1455599 ChemDiv3_000744 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)Nc2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B19 compound treatment 0.25 0.0192 2.65 0.246 0.0198 2.86 3.8992 0.9993 1507311 ChemDiv3_000745 CC(C)CN(CC(C)C)C(=O)c1cc2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B20 compound treatment 0.314 0.0832 11.49 0.305 0.0788 11.38 16.1774 1.0 3117540 ChemDiv3_000746 CCN1C(=O)/C(=C/Nc2ccccc2)/OC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B21 compound treatment 0.236 0.0052 0.72 0.236 0.00981 1.42 1.5102 0.9504 1429235 ChemDiv3_000747 CCOc1ccc(NC(=O)CCOc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B22 compound treatment 0.226 -0.0048 -0.66 0.221 -0.00519 -0.75 -0.9987 -0.9981 1159158 ChemDiv3_000748 O=C1CC(CC(=C1)NCc2ccco2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B23 mock treatment 0.237 0.0062 0.86 0.224 -0.00219 -0.32 0.3822 0.4187 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 B24 positive control 0.229 -0.0018 -0.25 0.223 -0.00319 -0.46 -0.5014 -0.9582 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C01 compound treatment 0.23 -8.0E-4 -0.11 0.231 0.00481 0.7 0.4134 0.5873 1611722 ChemDiv3_000749 CCOC(=O)C1=C(CC)NC2=C(C1c3ccccc3OCC)C(=O)CCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C02 compound treatment 0.257 0.0262 3.62 0.258 0.0318 4.6 5.8087 0.993 1332565 ChemDiv3_000750 CCOC(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C03 compound treatment 0.224 -0.0068 -0.94 0.221 -0.00519 -0.75 -1.1941 -0.9937 1451908 ChemDiv3_000751 CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN(C)C)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C04 compound treatment 0.231 2.0E-4 0.03 0.225 -0.00119 -0.17 -0.1018 -0.5857 2112223 ChemDiv3_000752 O=c1oc2ccccc2cc1c3cn4c(n3)sc5ccccc54 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C05 compound treatment 0.226 -0.0048 -0.66 0.217 -0.00919 -1.33 -1.4073 -0.9486 1471012 ChemDiv3_000753 S=C(Nc1ccccc1)N2CCCN2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C06 compound treatment 0.232 0.0012 0.17 0.226 -1.88E-4 -0.03 0.0981 0.5838 1915139 ChemDiv3_000754 NC(C(=O)O)c1ccc(CCCC(=O)O)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C07 compound treatment 0.248 0.0172 2.38 0.247 0.0208 3.01 3.806 0.9932 1351042 ChemDiv3_000755 O=C(Nc1ccccc1)Nc2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C08 compound treatment 0.403 0.172 23.79 0.403 0.177 25.54 34.8812 0.9994 3020820 ChemDiv3_000756 CN(/C=C\1/C=C(C)SC1=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C09 compound treatment 0.228 -0.0028 -0.39 0.223 -0.00319 -0.46 -0.5991 -0.9962 3117541 ChemDiv3_000757 Clc1ccc(C(=O)OCCCN2C(=O)c3ccccc3C2=O)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C10 compound treatment 0.22 -0.0108 -1.49 0.223 -0.00319 -0.46 -1.3806 -0.8842 1673647 ChemDiv3_000758 O=C1CC(OC21CCCCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C11 compound treatment 0.244 0.0132 1.82 0.246 0.0198 2.86 3.3131 0.9763 1920609 ChemDiv3_000759 FC(F)(F)c1ccccc1NC(=O)NC2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C12 compound treatment 0.226 -0.0048 -0.66 0.223 -0.00319 -0.46 -0.7945 -0.9841 1187258 ChemDiv3_000760 O=C(N(CC#N)CC#N)c1ccc(cc1)C(=O)N(CC#N)CC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C13 compound treatment 0.252 0.0212 2.93 0.257 0.0308 4.45 5.2181 0.9794 1351252 ChemDiv3_000761 CC(C)C(=O)Oc1ccc2c(c1)oc(=O)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C14 compound treatment 0.391 0.16 22.13 0.362 0.136 19.62 29.5212 0.9982 3117542 ChemDiv3_000762 Clc1ccc(Cn2c(/N=C/c3ccc4OCOc4c3)nc5ccccc25)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C15 compound treatment 0.339 0.108 14.95 0.343 0.117 16.87 22.5008 0.9982 1648199 ChemDiv3_000763 Nc1c(C#N)c2nc3ccccc3nc2n1c4ccc(O)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C16 compound treatment 0.247 0.0162 2.24 0.248 0.0218 3.15 3.8104 0.986 3117543 ChemDiv3_000764 Cc1ccc(Cn2c(/N=C/c3ccc(Br)cc3)nc4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C17 compound treatment 0.229 -0.0018 -0.25 0.229 0.00281 0.41 0.1114 0.2339 3020844 ChemDiv3_000765 CN(Cc1ccccc1)C(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C18 compound treatment 0.249 0.0182 2.51 0.254 0.0278 4.02 4.6186 0.9745 1586578 ChemDiv3_000766 Brc1ccc(cc1)C(=O)COC(=O)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C19 compound treatment 0.226 -0.0048 -0.66 0.226 -1.88E-4 -0.03 -0.4881 -0.7354 1919025 ChemDiv3_000767 FC(F)(F)c1cccc(NC(=O)COc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C20 compound treatment 0.228 -0.0028 -0.39 0.225 -0.00119 -0.17 -0.3948 -0.933 3020845 ChemDiv3_000768 NNC(=O)c1ccc(/C=N\O)nc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C21 compound treatment 0.265 0.0342 4.72 0.262 0.0358 5.17 6.9987 0.999 3020846 ChemDiv3_000769 Brc1ccc(NC(=O)/C=C/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C22 compound treatment 0.224 -0.0068 -0.94 0.221 -0.00519 -0.75 -1.1941 -0.9937 1510082 ChemDiv3_000770 OC(=O)CCC(=O)NCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C23 mock treatment 0.231 2.0E-4 0.03 0.225 -0.00119 -0.17 -0.1018 -0.5857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 C24 positive control 0.232 0.0012 0.17 0.226 -1.88E-4 -0.03 0.0981 0.5838 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D01 compound treatment 0.221 -0.0098 -1.35 0.224 -0.00219 -0.32 -1.1808 -0.8493 1123230 ChemDiv3_000771 Oc1ccccc1N2C(=O)C3CC=CCC3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D02 compound treatment 0.225 -0.0058 -0.8 0.222 -0.00419 -0.6 -0.9943 -0.9904 1485584 ChemDiv3_000772 CCN(CC)c1ccc(NC(=O)C(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D03 compound treatment 0.236 0.0052 0.72 0.233 0.00681 0.98 1.2038 0.988 3020847 ChemDiv3_000773 O=C(NN1C(=O)CSC1=S)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D04 compound treatment 0.217 -0.0138 -1.91 0.22 -0.00619 -0.89 -1.9801 -0.9404 3117544 ChemDiv3_000774 C(CSc1nc2ccccc2[nH]1)CN3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D05 compound treatment 0.254 0.0232 3.21 0.253 0.0268 3.87 5.0049 0.9956 1778456 ChemDiv3_000775 OC(=O)CC(Sc1nc2sc3CCCCc3c2c(=O)[nH]1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D06 compound treatment 0.244 0.0132 1.82 0.249 0.0228 3.3 3.6195 0.9611 3020848 ChemDiv3_000776 FC(F)(F)c1cccc(NC(=O)c2ccc3ccccc3c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D07 compound treatment 0.26 0.0292 4.03 0.263 0.0368 5.32 6.6124 0.9907 3020849 ChemDiv3_000777 Cc1sc(Nc2ccccc2F)nc1c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D08 compound treatment 0.242 0.0112 1.55 0.239 0.0128 1.85 2.4027 0.996 1364991 ChemDiv3_000778 Brc1cccc(c1)c2nnc(o2)c3cc4ccccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D09 compound treatment 0.222 -0.0088 -1.22 0.214 -0.0122 -1.76 -2.1045 -0.9837 3117545 ChemDiv3_000779 CCOC(=O)c1c(/N=c/2\oc3ccc4ccccc4c3cc2C(=O)N)sc5CCCCc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D10 compound treatment 0.218 -0.0128 -1.77 0.215 -0.0112 -1.62 -2.3931 -0.999 1665286 ChemDiv3_000780 CN1CCN(CC1)NC(=O)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D11 compound treatment 0.275 0.0442 6.11 0.281 0.0548 7.92 9.9163 0.9918 1652224 ChemDiv3_000781 COC(=O)COc1ccc-2c(c1)C(=NO)c3cc(OCC(=O)OC)ccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D12 compound treatment 0.308 0.0772 10.67 0.307 0.0808 11.67 15.7955 0.999 1235358 ChemDiv3_000782 CCC1Nc2ccccc2-c3nnc(SC)nc3O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D13 compound treatment 0.226 -0.0048 -0.66 0.22 -0.00619 -0.89 -1.1009 -0.9892 1443634 ChemDiv3_000783 OC(=O)C1C2CC=CC2c3cc(Cl)cc4C5C=CCC5CN1c43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D14 compound treatment 0.23 -8.0E-4 -0.11 0.239 0.0128 1.85 1.2305 0.6637 3020850 ChemDiv3_000784 Fc1cccc(c1)C2=N/C(=C\c3cccc4ccccc34)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D15 compound treatment 0.265 0.0342 4.72 0.269 0.0428 6.18 7.7137 0.9912 1569541 ChemDiv3_000785 CCOC(=O)c1cnn(c1N(C(=O)c2ccccc2F)C(=O)c3ccccc3F)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D16 compound treatment 0.316 0.0852 11.77 0.316 0.0898 12.97 17.4963 0.9988 3020851 ChemDiv3_000786 CC(=O)Nc1cccc(/N=C/c2cc(I)cc(C)c2O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D17 compound treatment 0.233 0.0022 0.3 0.234 0.00781 1.13 1.0129 0.8667 1355069 ChemDiv3_000787 CS(=O)(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D18 compound treatment 0.283 0.0522 7.21 0.278 0.0518 7.48 10.3913 0.9998 1626307 ChemDiv3_000788 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D19 compound treatment 0.221 -0.0098 -1.35 0.219 -0.00719 -1.04 -1.6915 -0.9914 3117546 ChemDiv3_000789 Cc1cc(C)c(C(=O)NCC=C)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D20 compound treatment 0.272 0.0412 5.69 0.271 0.0448 6.47 8.6018 0.9979 3117547 ChemDiv3_000790 CCN1/C(=C\2/C(=NN(C2=O)c3ccccc3)C)/C=Cc4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D21 compound treatment 0.217 -0.0138 -1.91 0.218 -0.00819 -1.18 -2.1843 -0.9736 1388884 ChemDiv3_000791 O=C(CCOc1ccccc1)NCc2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D22 compound treatment 0.241 0.0102 1.41 0.233 0.00681 0.98 1.6922 0.9846 3117548 ChemDiv3_000792 COc1ccccc1/C=C/2\SC(=O)N(CCC(=O)N3c4ccccc4Sc5ccccc35)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D23 mock treatment 0.229 -0.0018 -0.25 0.228 0.00181 0.26 0.0093 0.0257 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 D24 positive control 0.232 0.0012 0.17 0.227 8.12E-4 0.12 0.2002 0.9857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E01 compound treatment 0.29 0.0592 8.18 0.302 0.0758 10.95 13.5265 0.9897 1583492 ChemDiv3_000793 COC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(C)C)C(=O)CC(C2)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E02 compound treatment 0.241 0.0102 1.41 0.235 0.00881 1.27 1.8965 0.9987 1432876 ChemDiv3_000794 CCc1ccc(OCC(=O)Nc2ccc(OC)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E03 compound treatment 0.325 0.0942 13.01 0.275 0.0488 7.05 14.1878 0.9586 3117549 ChemDiv3_000795 COc1cccc(/C=C/C(=O)C2C(=O)c3ccccc3C2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E04 compound treatment 0.276 0.0452 6.24 0.277 0.0508 7.34 9.6054 0.9968 1606983 ChemDiv3_000796 Oc1cccc(NC(=O)c2c(O)c3ccccc3n(CC=C)c2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E05 compound treatment 0.255 0.0242 3.34 0.252 0.0258 3.73 5.0005 0.9985 1715553 ChemDiv3_000797 Cc1[nH]c2ccc(CN3C(=O)c4ccccc4C3=O)cc2c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E06 compound treatment 0.28 0.0492 6.8 0.275 0.0488 7.05 9.7919 0.9998 3020853 ChemDiv3_000798 COC(=O)c1cc(N)c(Cl)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E07 compound treatment 0.248 0.0172 2.38 0.245 0.0188 2.72 3.6017 0.9978 1915335 ChemDiv3_000799 FC(F)(F)c1cccc(NC(=O)Nc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E08 compound treatment 0.248 0.0172 2.38 0.24 0.0138 2.0 3.091 0.9962 1289585 ChemDiv3_000800 CC1(OC(=O)C2C1C3CCCCC3=C4CCCCC24)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E09 compound treatment 0.227 -0.0038 -0.52 0.224 -0.00219 -0.32 -0.5946 -0.9705 1304126 ChemDiv3_000801 O=C(N1CC(=O)Nc2ccccc12)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E10 compound treatment 0.223 -0.0078 -1.08 0.222 -0.00419 -0.6 -1.1897 -0.9627 1265761 ChemDiv3_000802 COc1cc(nc(OC)n1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E11 compound treatment 0.215 -0.0158 -2.18 0.222 -0.00419 -0.6 -1.9712 -0.8703 1735414 ChemDiv3_000803 COC(=O)c1ccc(OC(=O)CCN2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E12 compound treatment 0.224 -0.0068 -0.94 0.22 -0.00619 -0.89 -1.2963 -0.9997 3020873 ChemDiv3_000804 CN(c1ccccc1)S(=O)(=O)c2c(C)cc(C)cc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E13 compound treatment 0.224 -0.0068 -0.94 0.221 -0.00519 -0.75 -1.1941 -0.9937 1517748 ChemDiv3_000805 CN(C1CCCCC1)C(=O)COc2ccc(Cl)c(C)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E14 compound treatment 0.341 0.11 15.22 0.356 0.13 18.75 24.024 0.9947 1467248 ChemDiv3_000806 Cc1nc2n(Cc3ccccc3)c4ccccc4n2c1C(=S)Nc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E15 compound treatment 0.221 -0.0098 -1.35 0.215 -0.0112 -1.62 -2.1 -0.9961 1918958 ChemDiv3_000807 Clc1cccc(CC2SC(=N)NC2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E16 compound treatment 0.227 -0.0038 -0.52 0.22 -0.00619 -0.89 -1.0032 -0.9678 3020874 ChemDiv3_000808 CC(/N=C/c1nc2ccccc2n1C)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E17 compound treatment 0.232 0.0012 0.17 0.238 0.0118 1.71 1.3237 0.7722 3117550 ChemDiv3_000809 Cc1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E18 compound treatment 0.275 0.0442 6.11 0.271 0.0448 6.47 8.8949 0.9996 3117551 ChemDiv3_000810 COc1ccc(O)c(/C=N/CC(C)\N=C\c2cc(OC)ccc2O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E19 compound treatment 0.237 0.0062 0.86 0.236 0.00981 1.42 1.6079 0.9709 1413824 ChemDiv3_000811 COC(=O)c1ccccc1NC(=O)COc2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E20 compound treatment 0.262 0.0312 4.31 0.26 0.0338 4.88 6.5014 0.9981 1629872 ChemDiv3_000812 COc1ccccc1C(=O)Nc2ccc3oc(nc3c2)c4ccc5ccccc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E21 compound treatment 0.224 -0.0068 -0.94 0.22 -0.00619 -0.89 -1.2963 -0.9997 1625558 ChemDiv3_000813 COC(=O)c1cccc(NC(=O)c2ccccc2C(=O)O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E22 compound treatment 0.222 -0.0088 -1.22 0.219 -0.00719 -1.04 -1.5938 -0.9969 1326899 ChemDiv3_000814 COc1ccccc1N2CCN(CC2)C(=O)CCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E23 mock treatment 0.229 -0.0018 -0.25 0.224 -0.00219 -0.32 -0.3993 -0.993 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 E24 positive control 0.232 0.0012 0.17 0.231 0.00481 0.7 0.6088 0.8519 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F01 compound treatment 0.224 -0.0068 -0.94 0.223 -0.00319 -0.46 -0.9898 -0.9461 1373507 ChemDiv3_000815 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Cc3ccncc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F02 compound treatment 0.222 -0.0088 -1.22 0.214 -0.0122 -1.76 -2.1045 -0.9837 3020875 ChemDiv3_000816 O=C(NC1CCCC1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F03 compound treatment 0.255 0.0242 3.34 0.254 0.0278 4.02 5.2048 0.9958 1442394 ChemDiv3_000817 O=C(NCCc1ccccc1)c2ccccc2CN3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F04 compound treatment 0.219 -0.0118 -1.63 0.218 -0.00819 -1.18 -1.989 -0.9876 3020876 ChemDiv3_000818 FC(F)(F)c1nc2ccccc2n1CCOc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F05 compound treatment 0.222 -0.0088 -1.22 0.217 -0.00919 -1.33 -1.798 -0.999 3117552 ChemDiv3_000819 O=C(N/C(=C/c1ccccc1)/S(=O)(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F06 compound treatment 0.31 0.0792 10.94 0.334 0.108 15.57 18.7487 0.9851 3020877 ChemDiv3_000820 CCOc1ccc(cc1Br)C(=O)Nc2cccc(NC(=O)c3ccccc3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F07 compound treatment 0.226 -0.0048 -0.66 0.221 -0.00519 -0.75 -0.9987 -0.9981 3117553 ChemDiv3_000821 O=C(Nc1ccccc1)c2cnc[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F08 compound treatment 0.29 0.0592 8.18 0.288 0.0618 8.93 12.0965 0.999 1673072 ChemDiv3_000822 OC(C(=O)Nc1cc(Cl)ccc1Cl)(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F09 compound treatment 0.27 0.0392 5.42 0.276 0.0498 7.2 8.9171 0.9902 3020878 ChemDiv3_000823 CCN(CC)c1ccc2cc(C(=O)N)/c(=N/c3cccc(C)c3)/oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F10 compound treatment 0.228 -0.0028 -0.39 0.221 -0.00519 -0.75 -0.8034 -0.9527 3117554 ChemDiv3_000824 Fc1ccc(NC(=O)c2cnccn2)c(F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F11 compound treatment 0.221 -0.0098 -1.35 0.22 -0.00619 -0.89 -1.5893 -0.9797 1470949 ChemDiv3_000825 COc1ccc(cc1)c2ccc(OC)cc2C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F12 compound treatment 0.283 0.0522 7.21 0.282 0.0558 8.06 10.7999 0.9985 1687536 ChemDiv3_000826 CCN(CC)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)Oc2ccc(C)cc2n3nc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F13 compound treatment 0.263 0.0322 4.45 0.256 0.0298 4.31 6.1905 0.9999 1365314 ChemDiv3_000827 Clc1ccc2NC(C3CC=CC3c2c1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F14 compound treatment 0.271 0.0402 5.55 0.306 0.0798 11.53 12.079 0.9439 1517186 ChemDiv3_000828 Cc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F15 compound treatment 0.26 0.0292 4.03 0.272 0.0458 6.62 7.5317 0.9718 1513840 ChemDiv3_000829 COC(=O)C1=C(C)N(C(=C(C1c2ccccc2)C(=O)OC)C)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F16 compound treatment 0.271 0.0402 5.55 0.269 0.0428 6.18 8.2998 0.9986 3117555 ChemDiv3_000830 COc1cccc(/C=C\2/C(=O)NN(C2=O)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F17 compound treatment 0.223 -0.0078 -1.08 0.219 -0.00719 -1.04 -1.4961 -0.9998 3020879 ChemDiv3_000831 CS(=O)(=O)NCCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F18 compound treatment 0.222 -0.0088 -1.22 0.226 -1.88E-4 -0.03 -0.8788 -0.7227 1468720 ChemDiv3_000832 OC(=O)c1ccccc1C(=O)NC=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F19 compound treatment 0.225 -0.0058 -0.8 0.221 -0.00519 -0.75 -1.0964 -0.9994 3117556 ChemDiv3_000833 CC(C)c1ccc(/C=C/C(=O)NCC=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F20 compound treatment 0.222 -0.0088 -1.22 0.22 -0.00619 -0.89 -1.4916 -0.9886 3117557 ChemDiv3_000834 CC(C)CNC=C1C(=O)CC(C)(C)CC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F21 compound treatment 0.27 0.0392 5.42 0.261 0.0348 5.03 7.385 0.9993 1393505 ChemDiv3_000835 Cc1cc(C)cc(NC(=O)c2cc3ccccc3o2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F22 compound treatment 0.235 0.0042 0.58 0.231 0.00481 0.7 0.9018 0.996 3117558 ChemDiv3_000836 CN1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F23 mock treatment 0.23 -8.0E-4 -0.11 0.223 -0.00319 -0.46 -0.4037 -0.8526 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 F24 positive control 0.232 0.0012 0.17 0.227 8.12E-4 0.12 0.2002 0.9857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G01 compound treatment 0.337 0.106 14.67 0.329 0.103 14.85 20.8755 1.0 1690924 ChemDiv3_000837 COC(=O)C1=C(C)NC2=C(C1c3ccccc3)C(=O)CCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G02 compound treatment 0.221 -0.0098 -1.35 0.22 -0.00619 -0.89 -1.5893 -0.9797 1254482 ChemDiv3_000838 Cc1ccc(OCC(=O)NCc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G03 compound treatment 0.22 -0.0108 -1.49 0.221 -0.00519 -0.75 -1.5849 -0.9492 1006818 ChemDiv3_000839 OC(=O)CCCC(=O)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G04 compound treatment 0.24 0.0092 1.27 0.233 0.00681 0.98 1.5945 0.992 3117559 ChemDiv3_000840 CC(C)(C)c1ccc(cc1)C(=O)N2CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G05 compound treatment 0.237 0.0062 0.86 0.234 0.00781 1.13 1.4036 0.9907 1344674 ChemDiv3_000841 Clc1ccccc1C(=O)c2ccc3OCCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G06 compound treatment 0.235 0.0042 0.58 0.236 0.00981 1.42 1.4125 0.9223 1914993 ChemDiv3_000842 COC(=O)CCC(=O)c1cc(sc1C(C)(C)C)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G07 compound treatment 0.229 -0.0018 -0.25 0.223 -0.00319 -0.46 -0.5014 -0.9582 1342176 ChemDiv3_000843 CC1CCN(Cn2c(=S)oc3ccccc23)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G08 compound treatment 0.273 0.0422 5.83 0.268 0.0418 6.04 8.3931 0.9998 1917056 ChemDiv3_000844 FC(F)(F)COc1nc(nc(n1)N2CCCCC2)N(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G09 compound treatment 0.249 0.0182 2.51 0.251 0.0248 3.58 4.3122 0.985 1584064 ChemDiv3_000845 Cc1ccccc1OCC(=O)NC(c2ccccc2)c3c(O)ccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G10 compound treatment 0.266 0.0352 4.86 0.261 0.0348 5.03 6.9943 0.9999 1318907 ChemDiv3_000846 CCCc1nc(N)c(C#N)c(c1CC)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G11 compound treatment 0.257 0.0262 3.62 0.245 0.0188 2.72 4.4809 0.99 1607665 ChemDiv3_000847 O=C(NCCc1ccccc1)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G12 compound treatment 0.228 -0.0028 -0.39 0.223 -0.00319 -0.46 -0.5991 -0.9962 1316192 ChemDiv3_000848 CCN(Cc1ccccc1)S(=O)(=O)c2cc(Cl)ccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G13 compound treatment 0.233 0.0022 0.3 0.252 0.0258 3.73 2.8514 0.7622 3117560 ChemDiv3_000849 Clc1ccc(/C=C/C(=O)Nc2nccs2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G14 compound treatment 0.217 -0.0138 -1.91 0.22 -0.00619 -0.89 -1.9801 -0.9404 1342653 ChemDiv3_000850 Clc1ccc2[nH]c(nc2c1)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G15 compound treatment 0.223 -0.0078 -1.08 0.228 0.00181 0.26 -0.5768 -0.5202 1360061 ChemDiv3_000851 CCOc1ccccc1C(=O)Nc2cccc(C)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G16 compound treatment 0.225 -0.0058 -0.8 0.219 -0.00719 -1.04 -1.3007 -0.9918 1160846 ChemDiv3_000852 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(NC(=O)C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G17 compound treatment 0.226 -0.0048 -0.66 0.223 -0.00319 -0.46 -0.7945 -0.9841 3020907 ChemDiv3_000853 Cc1ccc(NC(=O)c2ccc(F)cc2)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G18 compound treatment 0.238 0.0072 0.99 0.23 0.00381 0.55 1.0928 0.9611 1569529 ChemDiv3_000854 Cc1ccc(NC(=O)c2nc[nH]c2C(=O)N3CCCCC3)c(c1)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G19 compound treatment 0.227 -0.0038 -0.52 0.222 -0.00419 -0.6 -0.7989 -0.9975 1657157 ChemDiv3_000855 CC(C)(C)C(=O)NC(c1ccccc1)c2c(O)ccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G20 compound treatment 0.221 -0.0098 -1.35 0.228 0.00181 0.26 -0.7722 -0.56 1709867 ChemDiv3_000856 COc1cccc(c1)C(=O)Nc2ccc3oc(nc3c2)c4cccc(I)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G21 compound treatment 0.241 0.0102 1.41 0.237 0.0108 1.56 2.1008 0.9987 1083894 ChemDiv3_000857 Clc1ccc(cc1)C(=O)NCCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G22 compound treatment 0.22 -0.0108 -1.49 0.218 -0.00819 -1.18 -1.8913 -0.9934 3117561 ChemDiv3_000858 COc1cccc(c1)C(C(F)(F)F)P(=O)(C)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G23 mock treatment 0.228 -0.0028 -0.39 0.226 -1.88E-4 -0.03 -0.2927 -0.7548 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 G24 positive control 0.231 2.0E-4 0.03 0.224 -0.00219 -0.32 -0.2039 -0.6428 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H01 compound treatment 0.224 -0.0068 -0.94 0.225 -0.00119 -0.17 -0.7856 -0.8226 1366343 ChemDiv3_000859 CC(=O)N(CN1C(=O)C2CC=CCC2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H02 compound treatment 0.228 -0.0028 -0.39 0.228 0.00181 0.26 -0.0884 -0.1893 1584378 ChemDiv3_000860 CCOC(=O)Cc1csc(NC(=O)c2ccccc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H03 compound treatment 0.298 0.0672 9.28 0.284 0.0578 8.35 12.4695 0.9986 3117562 ChemDiv3_000861 CC(C)c1ccc(C)cc1OCC(=O)/C=C/2\Sc3ccccc3N2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H04 compound treatment 0.285 0.0542 7.49 0.28 0.0538 7.77 10.791 0.9998 1622162 ChemDiv3_000862 Cc1ccccc1C(=O)Nc2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H05 compound treatment 0.425 0.194 26.83 0.419 0.193 27.85 38.6645 0.9998 3117563 ChemDiv3_000863 Cc1ccc(cc1)S(=O)(=O)NN2C(=O)S/C(=C/c3ccccc3)/C2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H06 compound treatment 0.507 0.276 38.16 0.497 0.271 39.12 54.6417 0.9999 3020908 ChemDiv3_000864 CSc1ccc(/C=C\2/SC(=O)N(CNc3ccccc3)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H07 compound treatment 0.255 0.0242 3.34 0.253 0.0268 3.87 5.1026 0.9973 1912608 ChemDiv3_000865 Oc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H08 compound treatment 0.282 0.0512 7.07 0.282 0.0558 8.06 10.7022 0.9979 1623791 ChemDiv3_000866 Cc1ccc(NC(=O)c2ccc(cc2)c3ccccc3)nc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H09 compound treatment 0.235 0.0042 0.58 0.234 0.00781 1.13 1.2082 0.9522 3117564 ChemDiv3_000867 COc1cccc2cc(c3csc(Nc4cccc(c4)C(F)(F)F)n3)c(=O)oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H10 compound treatment 0.271 0.0402 5.55 0.268 0.0418 6.04 8.1977 0.9991 3020909 ChemDiv3_000868 CC(C)(C)c1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H11 compound treatment 0.225 -0.0058 -0.8 0.226 -1.88E-4 -0.03 -0.5857 -0.7306 1919894 ChemDiv3_000869 CCS(=O)(=O)C(=C(Nc1ccccc1)Nc2ccccc2)S(=O)(=O)CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H12 compound treatment 0.221 -0.0098 -1.35 0.221 -0.00519 -0.75 -1.4872 -0.9611 1361150 ChemDiv3_000870 COC(=O)C(C(C)C)N1C(=O)C2C3CC(C=C3)C2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H13 compound treatment 0.235 0.0042 0.58 0.231 0.00481 0.7 0.9018 0.996 1526618 ChemDiv3_000871 Cc1c(Cl)cccc1NC(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H14 compound treatment 0.439 0.208 28.76 0.476 0.25 36.08 45.854 0.9937 3118161 ChemDiv3_000872 O=C(Nc1ccc(cc1)c2nc3c(ccc4ccccc34)o2)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H15 compound treatment 0.317 0.0862 11.91 0.306 0.0798 11.53 16.5726 0.9999 1157871 ChemDiv3_000873 O=C(COc1ccc2c(cc(=O)oc2c1)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H16 compound treatment 0.386 0.155 21.44 0.386 0.16 23.08 31.4841 0.9993 3118162 ChemDiv3_000874 Nc1nnnn1/N=C\c2ccc(O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H17 compound treatment 0.227 -0.0038 -0.52 0.224 -0.00219 -0.32 -0.5946 -0.9705 1288630 ChemDiv3_000875 CCOC(=O)c1ccccc1NS(=O)(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H18 compound treatment 0.296 0.0652 9.01 0.302 0.0758 10.95 14.1126 0.9953 1696480 ChemDiv3_000876 Cc1ccc(NCC(O)Cn2c3ccccc3c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H19 compound treatment 0.225 -0.0058 -0.8 0.219 -0.00719 -1.04 -1.3007 -0.9918 1434081 ChemDiv3_000877 CC(C)c1ccc(OCC(=O)NCC=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H20 compound treatment 0.229 -0.0018 -0.25 0.225 -0.00119 -0.17 -0.2971 -0.9836 3020910 ChemDiv3_000878 CC1(C)CC(=O)C(=CNCc2ccco2)C(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H21 compound treatment 0.236 0.0052 0.72 0.232 0.00581 0.84 1.1017 0.997 1350794 ChemDiv3_000879 COc1ccc(OC(=O)c2cc3ccccc3o2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H22 compound treatment 0.23 -8.0E-4 -0.11 0.23 0.00381 0.55 0.3113 0.5541 3020911 ChemDiv3_000880 O=c1[nH]nc(N2CCOCC2)c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H23 mock treatment 0.229 -0.0018 -0.25 0.229 0.00281 0.41 0.1114 0.2339 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 H24 positive control 0.235 0.0042 0.58 0.225 -0.00119 -0.17 0.289 0.4776 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I01 compound treatment 0.229 -0.0018 -0.25 0.228 0.00181 0.26 0.0093 0.0257 1682167 ChemDiv3_000881 CCOC(=O)C1=C(NC(=O)NC1c2ccc(OC)cc2)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I02 compound treatment 0.529 0.298 41.2 0.532 0.306 44.17 60.3657 0.9994 3020912 ChemDiv3_000882 C1CN(CCO1)c2ccc(C=Nn3cncn3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I03 compound treatment 0.246 0.0152 2.1 0.245 0.0188 2.72 3.4063 0.9919 1588286 ChemDiv3_000883 CCOc1ccccc1N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I04 compound treatment 0.218 -0.0128 -1.77 0.214 -0.0122 -1.76 -2.4952 -1.0 3118163 ChemDiv3_000884 Cc1ccc(C)c(c1)S(=O)(=O)NCCCn2ccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I05 compound treatment 0.226 -0.0048 -0.66 0.228 0.00181 0.26 -0.2838 -0.398 1319250 ChemDiv3_000885 O=C(Nc1ccc2-c3ccc(NC(=O)C4CCCCC4)cc3S(=O)(=O)c2c1)C5CCCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I06 compound treatment 0.222 -0.0088 -1.22 0.222 -0.00419 -0.6 -1.2874 -0.9481 3020913 ChemDiv3_000886 CC1NC(=O)NC1CCCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I07 compound treatment 0.223 -0.0078 -1.08 0.223 -0.00319 -0.46 -1.0875 -0.9281 1370690 ChemDiv3_000887 CCC1CCCCN1C(=O)CN2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I08 compound treatment 0.225 -0.0058 -0.8 0.222 -0.00419 -0.6 -0.9943 -0.9904 3020914 ChemDiv3_000888 CCC1(CC)Cc2ccccc2/C(=N/c3c(C)n(C)n(c4ccccc4)c3=O)/N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I09 compound treatment 0.254 0.0232 3.21 0.254 0.0278 4.02 5.1071 0.9937 3118164 ChemDiv3_000889 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cccc(c3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I10 compound treatment 0.24 0.0092 1.27 0.241 0.0148 2.14 2.4117 0.9691 3118165 ChemDiv3_000890 COc1ccc(Cl)cc1NC(=O)c2nc3nc(cc(n3n2)C(F)(F)F)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I11 compound treatment 0.219 -0.0118 -1.63 0.22 -0.00619 -0.89 -1.7847 -0.96 1696086 ChemDiv3_000891 CCc1ccc(OCC(=O)N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I12 compound treatment 0.222 -0.0088 -1.22 0.221 -0.00519 -0.75 -1.3895 -0.973 1643226 ChemDiv3_000892 OC(=O)CP(=O)(O)c1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I13 compound treatment 0.23 -8.0E-4 -0.11 0.227 8.12E-4 0.12 0.0048 0.03 3118166 ChemDiv3_000893 Clc1ccccc1/C=C/C(=O)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I14 compound treatment 0.231 2.0E-4 0.03 0.231 0.00481 0.7 0.5111 0.7346 3020915 ChemDiv3_000894 COc1ccccc1/C=N\c2ccc3n(Cc4ccccc4)c(C)nc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I15 compound treatment 0.217 -0.0138 -1.91 0.216 -0.0102 -1.47 -2.3886 -0.9918 1438926 ChemDiv3_000895 COC(=O)c1ccccc1NC(=O)c2ccccc2Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I16 compound treatment 0.224 -0.0068 -0.94 0.219 -0.00719 -1.04 -1.3984 -0.9988 1126074 ChemDiv3_000896 O=S(=O)(Cc1ccccc1)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I17 compound treatment 0.243 0.0122 1.69 0.243 0.0168 2.43 2.909 0.9841 3118167 ChemDiv3_000897 Clc1ccc(/C=C/C(=O)NCc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I18 compound treatment 0.231 2.0E-4 0.03 0.224 -0.00219 -0.32 -0.2039 -0.6428 3118168 ChemDiv3_000898 O=C1CS/C(=N\c2ccccc2)/N1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I19 compound treatment 0.234 0.0032 0.44 0.234 0.00781 1.13 1.1106 0.9163 1496753 ChemDiv3_000899 CC(=O)n1cc(c2ccncc2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I20 compound treatment 0.226 -0.0048 -0.66 0.22 -0.00619 -0.89 -1.1009 -0.9892 3118169 ChemDiv3_000900 CC(=O)NC(=O)c/1cc2ccccc2o\c1=N/c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I21 compound treatment 0.248 0.0172 2.38 0.238 0.0118 1.71 2.8867 0.9868 1085397 ChemDiv3_000901 Clc1ccccc1NC(=O)COc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I22 compound treatment 0.223 -0.0078 -1.08 0.222 -0.00419 -0.6 -1.1897 -0.9627 3020938 ChemDiv3_000902 CP(=O)(O)C(c1cccc(Cl)c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I23 mock treatment 0.232 0.0012 0.17 0.227 8.12E-4 0.12 0.2002 0.9857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 I24 positive control 0.234 0.0032 0.44 0.223 -0.00319 -0.46 -0.013 -0.0203 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J01 compound treatment 0.298 0.0672 9.28 0.314 0.0878 12.68 15.5336 0.9882 3118170 ChemDiv3_000903 O=C1NC(=O)/C(=C\c2c3ccccc3cc4ccccc24)/C(=O)N1c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J02 compound treatment 0.254 0.0232 3.21 0.248 0.0218 3.15 4.4942 1.0 1538193 ChemDiv3_000904 Cc1cccc(Nc2nc(C)cc(C)c2C#N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J03 compound treatment 0.706 0.475 65.65 0.661 0.435 62.81 90.8322 0.9998 3020939 ChemDiv3_000905 CC(C)C(=O)/C=C\1/Sc2ccccc2N1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J04 compound treatment 0.221 -0.0098 -1.35 0.221 -0.00519 -0.75 -1.4872 -0.9611 1399642 ChemDiv3_000906 CC(C)(C#CC(O)(c1ccccc1)c2ccccc2)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J05 compound treatment 0.301 0.0702 9.7 0.291 0.0648 9.36 13.4775 0.9998 3118171 ChemDiv3_000907 Clc1ccc(/C=C\2/SC(=O)N(NC(=O)c3ccccc3Cl)C2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J06 compound treatment 0.242 0.0112 1.55 0.242 0.0158 2.28 2.7092 0.982 1545446 ChemDiv3_000908 OC(=O)c1ccccc1n2c(=O)c3cc4c(=O)n(c5ccccc5C(=O)O)c(=O)c4cc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J07 compound treatment 0.229 -0.0018 -0.25 0.227 8.12E-4 0.12 -0.0929 -0.3377 1642929 ChemDiv3_000909 C(N1CCN(Cc2ccccc2)C1c3c[nH]c4ccccc34)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J08 compound treatment 0.288 0.0572 7.9 0.286 0.0598 8.64 11.6969 0.999 3118172 ChemDiv3_000910 FC(F)(F)c1cccc(NC(=O)c2ccc(cc2)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J09 compound treatment 0.258 0.0272 3.76 0.247 0.0208 3.01 4.7829 0.9939 3020940 ChemDiv3_000911 Ic1cccc(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J10 compound treatment 0.263 0.0322 4.45 0.262 0.0358 5.17 6.8034 0.9972 3118173 ChemDiv3_000912 Cc1cc(I)ccc1NC(=O)c2ccc(cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J11 compound treatment 0.24 0.0092 1.27 0.241 0.0148 2.14 2.4117 0.9691 1477505 ChemDiv3_000913 CCCS(=O)(=O)c1c(C(=O)OC)n2ccccc2c1S(=O)(=O)CCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J12 compound treatment 0.224 -0.0068 -0.94 0.226 -1.88E-4 -0.03 -0.6834 -0.7272 1130176 ChemDiv3_000914 Cc1cccc(NCN2C(=O)C3C4CC(C=C4)C3C2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J13 compound treatment 0.331 0.1 13.84 0.336 0.11 15.86 21.0044 0.9977 3020941 ChemDiv3_000915 O=C/1OC(=N\C1=C/Nc2ccccn2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J14 compound treatment 0.225 -0.0058 -0.8 0.233 0.00681 0.98 0.1292 0.1018 1478515 ChemDiv3_000916 CCCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J15 compound treatment 0.293 0.0622 8.59 0.282 0.0558 8.06 11.7768 0.9995 3118174 ChemDiv3_000917 CC(C)(C)NC(=O)CCCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J16 compound treatment 0.297 0.0662 9.15 0.294 0.0678 9.8 13.3932 0.9994 3020942 ChemDiv3_000918 Brc1ccc(cc1)C2=N/C(=C\Nc3ccccc3)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J17 compound treatment 0.235 0.0042 0.58 0.232 0.00581 0.84 1.004 0.9837 3118175 ChemDiv3_000919 OC(=O)CCCNc1n[nH]c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J18 compound treatment 0.226 -0.0048 -0.66 0.223 -0.00319 -0.46 -0.7945 -0.9841 1721267 ChemDiv3_000920 O=C1N(CN2CCCCC2)C(=O)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J19 compound treatment 0.232 0.0012 0.17 0.229 0.00281 0.41 0.4045 0.9219 1065790 ChemDiv3_000921 COc1ccc(NC(=S)NC2CCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J20 compound treatment 0.231 2.0E-4 0.03 0.23 0.00381 0.55 0.4089 0.7417 1923178 ChemDiv3_000922 CC1(C)CC(=O)C(=CNCC2CCCO2)C(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J21 compound treatment 0.226 -0.0048 -0.66 0.227 8.12E-4 0.12 -0.3859 -0.5731 1623304 ChemDiv3_000923 Cc1ccc(OC(=O)c2cc3ccccc3o2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J22 compound treatment 0.223 -0.0078 -1.08 0.219 -0.00719 -1.04 -1.4961 -0.9998 3118176 ChemDiv3_000924 CCOCc1c[nH]c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J23 mock treatment 0.232 0.0012 0.17 0.229 0.00281 0.41 0.4045 0.9219 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 J24 positive control 0.235 0.0042 0.58 0.229 0.00281 0.41 0.6976 0.9848 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K01 compound treatment 0.255 0.0242 3.34 0.254 0.0278 4.02 5.2048 0.9958 1216806 ChemDiv3_000925 CC(=O)OCCn1c(=O)[nH]c(=O)c2nsnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K02 compound treatment 0.242 0.0112 1.55 0.239 0.0128 1.85 2.4027 0.996 3118177 ChemDiv3_000926 CC(C)(C)c1cc(Cl)c(O)c(/N=C/c2ccccc2O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K03 compound treatment 0.321 0.0902 12.46 0.364 0.138 19.91 22.8874 0.9746 1915945 ChemDiv3_000927 CCOC(=O)/C=C(\C)/N1N=C2C(CCc3cc(OC)ccc23)C1c4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K04 compound treatment 0.222 -0.0088 -1.22 0.221 -0.00519 -0.75 -1.3895 -0.973 1496403 ChemDiv3_000928 Cc1cn(cn1)S(=O)(=O)c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K05 compound treatment 0.284 0.0532 7.35 0.282 0.0558 8.06 10.8976 0.9989 1637460 ChemDiv3_000929 CCOc1cc(ccc1O)c2cc(C)c3c(ccc4ccccc43)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K06 compound treatment 0.325 0.0942 13.01 0.316 0.0898 12.97 18.3755 1.0 3020943 ChemDiv3_000930 CCC1=C/C(=C/N(C)c2ccccc2)/C(=O)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K07 compound treatment 0.219 -0.0118 -1.63 0.225 -0.00119 -0.17 -1.274 -0.7772 1083865 ChemDiv3_000931 FC(F)(F)c1cccc(NC(=O)c2ccco2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K08 compound treatment 0.236 0.0052 0.72 0.241 0.0148 2.14 2.0209 0.8954 1678628 ChemDiv3_000932 NCCCc1nc2cc3ccccc3cc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K09 compound treatment 0.243 0.0122 1.69 0.245 0.0188 2.72 3.1133 0.9736 3118178 ChemDiv3_000933 CN(C)c1n[nH]c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K10 compound treatment 0.222 -0.0088 -1.22 0.222 -0.00419 -0.6 -1.2874 -0.9481 1535139 ChemDiv3_000934 NC(=O)C1CCN(CC1)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K11 compound treatment 0.264 0.0332 4.59 0.261 0.0348 5.03 6.7989 0.9989 3020944 ChemDiv3_000935 NN1C(=O)/C(=C\c2ccccc2)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K12 compound treatment 0.222 -0.0088 -1.22 0.222 -0.00419 -0.6 -1.2874 -0.9481 1729835 ChemDiv3_000936 C(Cn1c(Cc2ccccc2)nc3ccccc13)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K13 compound treatment 0.284 0.0532 7.35 0.289 0.0628 9.07 11.6126 0.9945 3020945 ChemDiv3_000937 CC1CCN(CC1)C(=O)/C=C/c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K14 compound treatment 0.271 0.0402 5.55 0.265 0.0388 5.61 7.8913 1.0 3118311 ChemDiv3_000938 Cc1nc2cc(/N=C\c3ccc(Cl)cc3)ccc2n1Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K15 compound treatment 0.221 -0.0098 -1.35 0.22 -0.00619 -0.89 -1.5893 -0.9797 3020946 ChemDiv3_000939 CCCCc1ccc(NC(=O)CC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K16 compound treatment 0.227 -0.0038 -0.52 0.228 0.00181 0.26 -0.1861 -0.3172 1129901 ChemDiv3_000940 O=S(=O)(Cc1ccccc1)Nn2cnnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K17 compound treatment 0.248 0.0172 2.38 0.255 0.0288 4.16 4.6231 0.9647 3020947 ChemDiv3_000941 CC(NC(=O)/C=C/c1ccccc1Cl)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K18 compound treatment 0.264 0.0332 4.59 0.271 0.0448 6.47 7.8203 0.9858 3020310 ChemDiv3_000942 CCOc1ccc(OCCSc2nc3ccccc3n2Cc4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K19 compound treatment 0.237 0.0062 0.86 0.226 -1.88E-4 -0.03 0.5865 0.6844 1632334 ChemDiv3_000943 CCOC(=O)c1ccccc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K20 compound treatment 0.235 0.0042 0.58 0.241 0.0148 2.14 1.9232 0.8675 3118312 ChemDiv3_000944 CCOc1cccc2cc(C(=O)N)/c(=N/Cc3ccccc3)/oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K21 compound treatment 0.219 -0.0118 -1.63 0.217 -0.00919 -1.33 -2.0911 -0.9948 1564768 ChemDiv3_000945 COC(=O)c1cccc(NC(=O)COc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K22 compound treatment 0.231 2.0E-4 0.03 0.23 0.00381 0.55 0.4089 0.7417 1122886 ChemDiv3_000946 COC(=O)C1=C(C)NC(=O)CC1c2ccccc2I 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K23 mock treatment 0.231 2.0E-4 0.03 0.229 0.00281 0.41 0.3068 0.7535 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 K24 positive control 0.232 0.0012 0.17 0.229 0.00281 0.41 0.4045 0.9219 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L01 compound treatment 0.22 -0.0108 -1.49 0.224 -0.00219 -0.32 -1.2785 -0.8383 1725902 ChemDiv3_000947 CCOC(=O)CSc1nc2ccccc2o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L02 compound treatment 0.241 0.0102 1.41 0.246 0.0198 2.86 3.02 0.9467 3118313 ChemDiv3_000948 Clc1cccc(c1)C2OCC3(CO2)COC(OC3)c4cccc(Cl)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L03 compound treatment 0.23 -8.0E-4 -0.11 0.231 0.00481 0.7 0.4134 0.5873 3020311 ChemDiv3_000949 Clc1ccc(/C=C\2/C=C(OC2=O)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L04 compound treatment 0.247 0.0162 2.24 0.247 0.0208 3.01 3.7083 0.9894 1215566 ChemDiv3_000950 COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L05 compound treatment 0.224 -0.0068 -0.94 0.221 -0.00519 -0.75 -1.1941 -0.9937 1482448 ChemDiv3_000951 Clc1ccc(OCC(=O)NC2CCS(=O)(=O)C2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L06 compound treatment 0.226 -0.0048 -0.66 0.221 -0.00519 -0.75 -0.9987 -0.9981 3118314 ChemDiv3_000952 O=C1CCC(=O)N1c2nccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L07 compound treatment 0.233 0.0022 0.3 0.229 0.00281 0.41 0.5022 0.9898 1240764 ChemDiv3_000953 Oc1ccccc1C2N(Cc3ccccc3)CCN2Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L08 compound treatment 0.243 0.0122 1.69 0.244 0.0178 2.57 3.0111 0.979 1351151 ChemDiv3_000954 Clc1c(sc2ccccc12)C(=O)NCc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L09 compound treatment 0.227 -0.0038 -0.52 0.224 -0.00219 -0.32 -0.5946 -0.9705 1921190 ChemDiv3_000955 Nc1nnc(CCS(=O)(=O)c2ccc(Br)cc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L10 compound treatment 0.226 -0.0048 -0.66 0.228 0.00181 0.26 -0.2838 -0.398 1668007 ChemDiv3_000956 O=C(Nc1cccnc1)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L11 compound treatment 0.218 -0.0128 -1.77 0.217 -0.00919 -1.33 -2.1888 -0.99 3118315 ChemDiv3_000957 CN1CNC(=NS(=O)(=O)c2ccc(C)cc2)NC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L12 compound treatment 0.219 -0.0118 -1.63 0.22 -0.00619 -0.89 -1.7847 -0.96 1733849 ChemDiv3_000958 COC(=O)c1ccc(NC(=O)C2C(C3CCC2C3)C(=O)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L13 compound treatment 0.547 0.316 43.68 0.52 0.294 42.44 60.8984 0.9999 3020312 ChemDiv3_000959 O=C/1OC(=N\C1=C/N2CCCCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L14 compound treatment 0.23 -8.0E-4 -0.11 0.236 0.00981 1.42 0.9241 0.65 1222654 ChemDiv3_000960 CCCOc1ccc(cc1)C(=O)Nc2ccc-3c(Cc4ccccc43)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L15 compound treatment 0.223 -0.0078 -1.08 0.219 -0.00719 -1.04 -1.4961 -0.9998 3020313 ChemDiv3_000961 Cc1cccc(/N=C/2\SCC(=O)N2c3cccc(C)c3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L16 compound treatment 0.222 -0.0088 -1.22 0.223 -0.00319 -0.46 -1.1852 -0.9117 3118316 ChemDiv3_000962 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)CCN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L17 compound treatment 0.247 0.0162 2.24 0.248 0.0218 3.15 3.8104 0.986 3020314 ChemDiv3_000963 CCCOC(=O)c1ccc(NC(=O)/C=C/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L18 compound treatment 0.299 0.0682 9.42 0.291 0.0648 9.36 13.2821 1.0 3118317 ChemDiv3_000964 CCCCN1C(=O)/C(=C/N(C(=O)C)c2ccccc2)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L19 compound treatment 0.222 -0.0088 -1.22 0.224 -0.00219 -0.32 -1.0831 -0.8622 1677249 ChemDiv3_000965 CCc1cccc(C)c1NC(=O)C2COc3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L20 compound treatment 0.228 -0.0028 -0.39 0.227 8.12E-4 0.12 -0.1905 -0.4714 3118318 ChemDiv3_000966 COc1ccc(CNC=C2C(=O)CC(C)(C)CC2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L21 compound treatment 0.32 0.0892 12.32 0.321 0.0948 13.7 18.3977 0.9986 3118319 ChemDiv3_000967 Clc1ccc(/C=C/2\SC(=O)N(CC(=O)Nc3cccnc3)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L22 compound treatment 0.222 -0.0088 -1.22 0.22 -0.00619 -0.89 -1.4916 -0.9886 3020315 ChemDiv3_000968 CN(/C(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2)c3ccc(O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L23 mock treatment 0.23 -8.0E-4 -0.11 0.232 0.00581 0.84 0.5155 0.6088 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 L24 positive control 0.23 -8.0E-4 -0.11 0.228 0.00181 0.26 0.107 0.3764 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M01 compound treatment 0.233 0.0022 0.3 0.231 0.00481 0.7 0.7065 0.9312 3118320 ChemDiv3_000969 OC(=O)c1ccc(/N=C/c2cn(Cc3ccccc3)c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M02 compound treatment 0.264 0.0332 4.59 0.264 0.0378 5.46 7.1053 0.9962 3020316 ChemDiv3_000970 Fc1ccc(cc1)c2nc3cc(/N=C/C=C/c4ccc5OCOc5c4)ccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M03 compound treatment 0.228 -0.0028 -0.39 0.23 0.00381 0.55 0.1159 0.1722 3118321 ChemDiv3_000971 COc1ccc2CC/C(=C\c3ccc(cc3)N(C)C)/C(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M04 compound treatment 0.226 -0.0048 -0.66 0.226 -1.88E-4 -0.03 -0.4881 -0.7354 1918339 ChemDiv3_000972 CC(C)(C)S(=O)(=O)c1ccc(s1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M05 compound treatment 0.229 -0.0018 -0.25 0.225 -0.00119 -0.17 -0.2971 -0.9836 1679374 ChemDiv3_000973 CCc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M06 compound treatment 0.305 0.0742 10.25 0.304 0.0778 11.24 15.1961 0.9989 3118322 ChemDiv3_000974 CCC1=C/C(=C\c2ccc3OCOc3c2)/C(=O)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M07 compound treatment 0.229 -0.0018 -0.25 0.228 0.00181 0.26 0.0093 0.0257 3118323 ChemDiv3_000975 Brc1ccc2NC(=O)/C(=C/3\SC(=S)N(C3=O)c4cccc(Br)c4)/c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M08 compound treatment 0.228 -0.0028 -0.39 0.228 0.00181 0.26 -0.0884 -0.1893 1260425 ChemDiv3_000976 OC(=O)c1cncc(OC(=O)OCc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M09 compound treatment 0.226 -0.0048 -0.66 0.225 -0.00119 -0.17 -0.5902 -0.8617 1445337 ChemDiv3_000977 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M10 compound treatment 0.223 -0.0078 -1.08 0.219 -0.00719 -1.04 -1.4961 -0.9998 1228370 ChemDiv3_000978 COc1ccc(cc1)S(=O)(=O)N2CCCCC2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M11 compound treatment 0.225 -0.0058 -0.8 0.221 -0.00519 -0.75 -1.0964 -0.9994 1353970 ChemDiv3_000979 CCS(=O)(=O)c1ccc(O)c(NC(=O)COc2ccc(OC)cc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M12 compound treatment 0.291 0.0602 8.32 0.292 0.0658 9.51 12.6028 0.9978 3020317 ChemDiv3_000980 Brc1ccc(/C=N/c2nc3ccccc3n2CCN4CCCCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M13 compound treatment 0.225 -0.0058 -0.8 0.225 -0.00119 -0.17 -0.6879 -0.8395 1731333 ChemDiv3_000981 CCOC(=O)c1cccc(NC(=O)c2ccccc2Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M14 compound treatment 0.291 0.0602 8.32 0.295 0.0688 9.94 12.9092 0.9961 3020318 ChemDiv3_000982 CN(C)c1ccc(/C=N/c2ccc3n(cnc3c2)c4ccc(C)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M15 compound treatment 0.23 -8.0E-4 -0.11 0.222 -0.00419 -0.6 -0.5059 -0.8227 1678613 ChemDiv3_000983 CCOc1ccccc1C(=O)Nc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M16 compound treatment 0.225 -0.0058 -0.8 0.221 -0.00519 -0.75 -1.0964 -0.9994 1685159 ChemDiv3_000984 CC1CC(C)CN(C1)C(=O)c2c(C)onc2c3ccccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M17 compound treatment 0.28 0.0492 6.8 0.283 0.0568 8.21 10.609 0.9956 3020319 ChemDiv3_000985 CC(NC(=O)/C=C/c1ccc2OCOc2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M18 compound treatment 0.252 0.0212 2.93 0.263 0.0368 5.32 5.8309 0.9605 3118324 ChemDiv3_000986 CCOc1ccc(OCCSc2nc(=O)cc(C)[nH]2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M19 compound treatment 0.228 -0.0028 -0.39 0.225 -0.00119 -0.17 -0.3948 -0.933 1635077 ChemDiv3_000987 NC(=O)CCN1C(=O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M20 compound treatment 0.223 -0.0078 -1.08 0.224 -0.00219 -0.32 -0.9854 -0.8775 1419414 ChemDiv3_000988 C(CN1CCOCC1)Cc2ccc(COc3ccccc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M21 compound treatment 0.266 0.0352 4.86 0.268 0.0418 6.04 7.7093 0.9942 1606786 ChemDiv3_000989 COC(=O)c1ccccc1NC(=O)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M22 compound treatment 0.264 0.0332 4.59 0.278 0.0518 7.48 8.5353 0.9724 1273253 ChemDiv3_000990 CNS(=O)(=O)c1ccc-2c(c1)C(=NO)c3cc(ccc32)S(=O)(=O)NC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M23 mock treatment 0.233 0.0022 0.3 0.228 0.00181 0.26 0.4 0.9972 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 M24 positive control 0.226 -0.0048 -0.66 0.227 8.12E-4 0.12 -0.3859 -0.5731 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N01 compound treatment 0.223 -0.0078 -1.08 0.228 0.00181 0.26 -0.5768 -0.5202 1426304 ChemDiv3_000991 Cc1cc(C)cc(OC(=O)CCN2C(=O)c3ccccc3C2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N02 compound treatment 0.223 -0.0078 -1.08 0.217 -0.00919 -1.33 -1.7004 -0.9947 3020320 ChemDiv3_000992 Brc1ccc(cc1)C2OCC(CO2)OC(=O)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N03 compound treatment 0.232 0.0012 0.17 0.241 0.0148 2.14 1.6301 0.7596 1721013 ChemDiv3_000993 Clc1ccc(cc1Cl)C(=O)NCCc2nc3ccccc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N04 compound treatment 0.227 -0.0038 -0.52 0.23 0.00381 0.55 0.0182 0.0239 3020321 ChemDiv3_000994 Brc1ccc(cc1)S(=O)(=O)/N=C(\Nc2ccccc2)/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N05 compound treatment 0.226 -0.0048 -0.66 0.227 8.12E-4 0.12 -0.3859 -0.5731 1559580 ChemDiv3_000995 CCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N06 compound treatment 0.229 -0.0018 -0.25 0.226 -1.88E-4 -0.03 -0.195 -0.7795 3020344 ChemDiv3_000996 CSc1ccc(/C=c\2/sc3nc4c(C)c(C)ccc4n3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N07 compound treatment 0.294 0.0632 8.73 0.304 0.0778 11.24 14.1215 0.9922 1921413 ChemDiv3_000997 CC(=O)Nc1ccc(NC(=O)/C=C/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N08 compound treatment 0.216 -0.0148 -2.04 0.229 0.00281 0.41 -1.1585 -0.5557 1649360 ChemDiv3_000998 CC(C)c1ccc(NC(=O)c2cccnc2Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N09 compound treatment 0.218 -0.0128 -1.77 0.22 -0.00619 -0.89 -1.8824 -0.95 1551746 ChemDiv3_000999 CC(=O)Nc1nnc(CCS(=O)(=O)c2ccc(C)cc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N10 compound treatment 0.271 0.0402 5.55 0.286 0.0598 8.64 10.0362 0.9772 3118325 ChemDiv3_001000 Oc1ccccc1NC(=S)NC(=O)/C=C/c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N11 compound treatment 0.22 -0.0108 -1.49 0.215 -0.0112 -1.62 -2.1977 -0.9992 3118597 ChemDiv3_001001 NC(=NS(=O)(=O)c1ccc(NC(=O)OC2CCCC2)cc1)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N12 compound treatment 0.219 -0.0118 -1.63 0.217 -0.00919 -1.33 -2.0911 -0.9948 1270195 ChemDiv3_001002 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N13 compound treatment 0.235 0.0042 0.58 0.24 0.0138 2.0 1.8211 0.8764 3118453 ChemDiv3_001003 O=S(=O)(/N=C(\OC1CCCCC1)/c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N14 compound treatment 0.232 0.0012 0.17 0.231 0.00481 0.7 0.6088 0.8519 1241887 ChemDiv3_001004 CCCOc1cccc(c1)C(=O)Nc2ccc(cc2)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N15 compound treatment 0.298 0.0672 9.28 0.303 0.0768 11.1 14.4101 0.9961 3020346 ChemDiv3_001005 COc1ccccc1N2C(=O)S/C(=C\c3ccccc3)/C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N16 compound treatment 0.229 -0.0018 -0.25 0.231 0.00481 0.7 0.3157 0.4276 1373892 ChemDiv3_001006 CC(=C)Cn1c(SCC(=O)NN)nc2ccccc2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N17 compound treatment 0.245 0.0142 1.96 0.243 0.0168 2.43 3.1044 0.9944 1493653 ChemDiv3_001007 CC(C)c1ccccc1NC(=O)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N18 compound treatment 0.338 0.107 14.81 0.33 0.104 15.0 21.0754 1.0 3118454 ChemDiv3_001008 CC(=O)N(/C=C/1\SC(=S)N(Cc2ccccc2)C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N19 compound treatment 0.224 -0.0068 -0.94 0.223 -0.00319 -0.46 -0.9898 -0.9461 1232650 ChemDiv3_001009 CCOC(=O)c1cccc(NC(=O)CCOc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N20 compound treatment 0.227 -0.0038 -0.52 0.228 0.00181 0.26 -0.1861 -0.3172 3118455 ChemDiv3_001010 CC1(C)CC(=O)C(=CNCc2cccnc2)C(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N21 compound treatment 0.236 0.0052 0.72 0.234 0.00781 1.13 1.3059 0.9762 3118456 ChemDiv3_001011 CN1CCN(CC1)NC(=O)CN2C(=O)S/C(=C/c3ccc(Cl)cc3)/C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N22 compound treatment 0.22 -0.0108 -1.49 0.221 -0.00519 -0.75 -1.5849 -0.9492 1118985 ChemDiv3_001012 COc1ccccc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N23 mock treatment 0.23 -8.0E-4 -0.11 0.226 -1.88E-4 -0.03 -0.0973 -0.8551 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 N24 positive control 0.229 -0.0018 -0.25 0.226 -1.88E-4 -0.03 -0.195 -0.7795 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O01 compound treatment 0.271 0.0402 5.55 0.275 0.0488 7.05 8.9127 0.993 3118457 ChemDiv3_001013 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)c3ccccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O02 compound treatment 0.238 0.0072 0.99 0.236 0.00981 1.42 1.7056 0.985 3020347 ChemDiv3_001014 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O03 compound treatment 0.223 -0.0078 -1.08 0.22 -0.00619 -0.89 -1.3939 -0.9957 1433689 ChemDiv3_001015 COc1ccc(cc1OC)C2CC(=NN2C=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O04 compound treatment 0.258 0.0272 3.76 0.25 0.0238 3.44 5.0893 0.999 1216374 ChemDiv3_001016 CC1(C)CC(=CC(C)(C)N1)c2ccc(s2)C3=CC(C)(C)NC(C)(C)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O05 compound treatment 0.262 0.0312 4.31 0.271 0.0448 6.47 7.6249 0.9805 1687051 ChemDiv3_001017 Oc1cccc(c1)c2nc3ccc4ccccc4c3c5CCCCc25 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O06 compound treatment 0.373 0.142 19.65 0.372 0.146 21.06 28.7842 0.9994 3020348 ChemDiv3_001018 CCc1cc2c[n+](sc2s1)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O07 compound treatment 0.265 0.0342 4.72 0.266 0.0398 5.75 7.4073 0.9952 1282936 ChemDiv3_001019 Cc1cc(=O)oc2cc(OCC(=O)O)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O08 compound treatment 0.226 -0.0048 -0.66 0.222 -0.00419 -0.6 -0.8966 -0.9989 1606633 ChemDiv3_001020 CC(=O)Oc1cncc(c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O09 compound treatment 0.235 0.0042 0.58 0.234 0.00781 1.13 1.2082 0.9522 1192059 ChemDiv3_001021 O=C(NCc1ccccc1)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O10 compound treatment 0.22 -0.0108 -1.49 0.215 -0.0112 -1.62 -2.1977 -0.9992 1475559 ChemDiv3_001022 COc1ccc(cc1)C(=O)NCC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O11 compound treatment 0.283 0.0522 7.21 0.272 0.0458 6.62 9.7785 0.9991 1080178 ChemDiv3_001023 Clc1ccc(cc1)C(=O)NC(=S)Nc2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O12 compound treatment 0.285 0.0542 7.49 0.312 0.0858 12.4 14.0594 0.9709 3118458 ChemDiv3_001024 Clc1ccc(/C=N/c2nc3ccccc3n2CC=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O13 compound treatment 0.218 -0.0128 -1.77 0.226 -1.88E-4 -0.03 -1.2696 -0.7179 1649330 ChemDiv3_001025 O=C(CNC(=O)c1ccccc1)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O14 compound treatment 0.321 0.0902 12.46 0.351 0.125 18.03 21.5596 0.9837 3118459 ChemDiv3_001026 COc1ccccc1n2cnc3cc(/N=C/c4ccccc4O)ccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O15 compound treatment 0.223 -0.0078 -1.08 0.219 -0.00719 -1.04 -1.4961 -0.9998 1328150 ChemDiv3_001027 Cc1ccc(cc1)N(C2CS(=O)(=O)CC2OC(=O)c3ccccc3)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O16 compound treatment 0.249 0.0182 2.51 0.258 0.0318 4.6 5.0272 0.9597 1283075 ChemDiv3_001028 COc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O17 compound treatment 0.273 0.0422 5.83 0.272 0.0458 6.62 8.8016 0.998 3118460 ChemDiv3_001029 Cc1ccccc1NC(=O)/C=C/c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O18 compound treatment 0.219 -0.0118 -1.63 0.219 -0.00719 -1.04 -1.8868 -0.9763 1317231 ChemDiv3_001030 NNC(=O)CNC(=O)C1COc2ccccc2O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O19 compound treatment 0.219 -0.0118 -1.63 0.223 -0.00319 -0.46 -1.4783 -0.8727 1195157 ChemDiv3_001031 COc1ccc(CCNC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O20 compound treatment 0.245 0.0142 1.96 0.245 0.0188 2.72 3.3086 0.9872 3020350 ChemDiv3_001032 OC(=O)C/1=NN(C(=O)\C1=C/c2c[nH]c3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O21 compound treatment 0.224 -0.0068 -0.94 0.219 -0.00719 -1.04 -1.3984 -0.9988 1154870 ChemDiv3_001033 COc1ccc(NC(=O)COc2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O22 compound treatment 0.247 0.0162 2.24 0.252 0.0258 3.73 4.219 0.9702 1195792 ChemDiv3_001034 CCNS(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)NCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O23 mock treatment 0.231 2.0E-4 0.03 0.225 -0.00119 -0.17 -0.1018 -0.5857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 O24 positive control 0.226 -0.0048 -0.66 0.221 -0.00519 -0.75 -0.9987 -0.9981 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P01 compound treatment 0.224 -0.0068 -0.94 0.231 0.00481 0.7 -0.1727 -0.1478 1266216 ChemDiv3_001035 Cc1cccc(C)c1OC(=O)CN2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P02 compound treatment 0.238 0.0072 0.99 0.234 0.00781 1.13 1.5013 0.998 3118461 ChemDiv3_001036 Cc1ccccc1OCCn2c(S)nc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P03 compound treatment 0.222 -0.0088 -1.22 0.227 8.12E-4 0.12 -0.7767 -0.6359 1270060 ChemDiv3_001037 O=C(NC1CCCC1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P04 compound treatment 0.221 -0.0098 -1.35 0.219 -0.00719 -1.04 -1.6915 -0.9914 3020351 ChemDiv3_001038 Cc1ccccc1N/C(=N\S(=O)(=O)c2ccccc2)/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P05 compound treatment 0.258 0.0272 3.76 0.271 0.0448 6.47 7.2342 0.9665 1725017 ChemDiv3_001039 COc1ccc(CC(C)CC(=O)Nc2ccc(I)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P06 compound treatment 0.3 0.0692 9.56 0.27 0.0438 6.33 11.2349 0.9799 1202851 ChemDiv3_001040 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4ccccc4Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P07 compound treatment 0.263 0.0322 4.45 0.301 0.0748 10.81 10.7868 0.923 1528263 ChemDiv3_001041 COc1ccc(NCC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P08 compound treatment 0.225 -0.0058 -0.8 0.223 -0.00319 -0.46 -0.8922 -0.9654 1730700 ChemDiv3_001042 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3Br)cc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P09 compound treatment 0.242 0.0112 1.55 0.237 0.0108 1.56 2.1985 1.0 3020380 ChemDiv3_001043 COc1ccc-2c(c1)C(=NN)c3cc(OC)ccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P10 compound treatment 0.245 0.0142 1.96 0.235 0.00881 1.27 2.2873 0.9781 3118462 ChemDiv3_001044 OC(=O)CCN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3Cl)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P11 compound treatment 0.218 -0.0128 -1.77 0.217 -0.00919 -1.33 -2.1888 -0.99 1544835 ChemDiv3_001045 CC(C)OC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P12 compound treatment 0.218 -0.0128 -1.77 0.223 -0.00319 -0.46 -1.576 -0.8625 3118463 ChemDiv3_001046 CCN1/C(=C\2/SC(=S)N(N)C2=O)/C=Cc3cc(C)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P13 compound treatment 0.225 -0.0058 -0.8 0.228 0.00181 0.26 -0.3815 -0.4525 3118464 ChemDiv3_001047 CCS(=O)(=O)CCc1nnc(NC(=O)Nc2cccc(c2)C(F)(F)F)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P14 compound treatment 0.271 0.0402 5.55 0.288 0.0618 8.93 10.2405 0.9739 1403310 ChemDiv3_001048 CCOc1ccc(NC(=O)c2cc3ccccc3o2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P15 compound treatment 0.227 -0.0038 -0.52 0.226 -1.88E-4 -0.03 -0.3904 -0.7426 3118465 ChemDiv3_001049 COc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccc(C)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P16 compound treatment 0.279 0.0482 6.66 0.277 0.0508 7.34 9.8985 0.9988 3020381 ChemDiv3_001050 CN(C)c1ccc(/C=C/c2ccncc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P17 compound treatment 0.238 0.0072 0.99 0.233 0.00681 0.98 1.3992 1.0 1724755 ChemDiv3_001051 CCc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P18 compound treatment 0.239 0.0082 1.13 0.246 0.0198 2.86 2.8247 0.9177 3020382 ChemDiv3_001052 CN1C(=O)/C(=C/Nc2ccccc2)/OC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P19 compound treatment 0.223 -0.0078 -1.08 0.224 -0.00219 -0.32 -0.9854 -0.8775 1157486 ChemDiv3_001053 Cc1cccc(NC(=O)CCOc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P20 compound treatment 0.225 -0.0058 -0.8 0.228 0.00181 0.26 -0.3815 -0.4525 1218521 ChemDiv3_001054 CCOP(=S)(OCC)SCSn1c(=O)oc2cc(Cl)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P21 compound treatment 0.246 0.0152 2.1 0.251 0.0248 3.58 4.0192 0.9676 3118466 ChemDiv3_001055 O=C/1N(C(=S)S\C1=C\c2cccs2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P22 compound treatment 0.227 -0.0038 -0.52 0.217 -0.00919 -1.33 -1.3096 -0.9176 3020383 ChemDiv3_001056 CC(Oc1ccc(Br)cc1)C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P23 mock treatment 0.23 -8.0E-4 -0.11 0.227 8.12E-4 0.12 0.0048 0.03 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2003 P24 positive control 0.235 0.0042 0.58 0.224 -0.00219 -0.32 0.1869 0.2828 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A01 compound treatment 0.212 -0.0195 -2.69 0.214 -0.0176 -2.55 -3.7018 -0.9996 3025482 ChemDiv3_005281 Cc1nc(CSc2nnc3scc(c4ccccc4)n23)cs1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A02 compound treatment 0.214 -0.0175 -2.41 0.22 -0.0116 -1.68 -2.8936 -0.9843 3118094 ChemDiv3_005282 COc1cc2nc(oc(=O)c2cc1OC)c3ccc4C(=O)N(CC(C)C)C(=O)c4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A03 compound treatment 0.216 -0.0155 -2.14 0.219 -0.0126 -1.82 -2.8004 -0.9969 1863770 ChemDiv3_005283 COc1cc(CNC2C3CC4CC(C3)CC2C4)ccc1OCc5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A04 compound treatment 0.211 -0.0205 -2.83 0.215 -0.0166 -2.4 -3.6974 -0.9967 1692810 ChemDiv3_005284 CCN(CC)C(=O)CSc1nc2n(C)c(=O)n(C)c(=O)c2n1CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A05 compound treatment 0.344 0.113 15.55 0.33 0.0984 14.21 21.041 0.999 3118095 ChemDiv3_005285 CC/N=C/1\S/C(=C\c2cn(CC(=O)Nc3cccc(C)c3)c4ccccc24)/C(=O)N1CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A06 compound treatment 0.233 0.00153 0.21 0.236 0.00437 0.63 0.5966 0.8952 3025483 ChemDiv3_005286 CCCCn1c(nc2c(=O)oc3ccccc3c12)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A07 compound treatment 0.251 0.0195 2.7 0.244 0.0124 1.79 3.1721 0.98 3025484 ChemDiv3_005287 O=C1N(CCn2c(=O)oc3ccccc23)C(=O)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A08 compound treatment 0.248 0.0165 2.28 0.243 0.0114 1.64 2.7769 0.9869 3118096 ChemDiv3_005288 CC(C)c1ccc(cc1)C2Nc3ccccc3S(=O)(=O)N2Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A09 compound treatment 0.211 -0.0205 -2.83 0.213 -0.0186 -2.69 -3.9017 -0.9997 3118097 ChemDiv3_005289 COc1ccc(NC(=O)C2CC(=O)N(C(=O)N2NC(=O)c3ccncc3)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A10 compound treatment 0.374 0.143 19.69 0.39 0.158 22.88 30.0999 0.9972 3025485 ChemDiv3_005290 Cc1cc(/C=C\2/C(=N)N3C=CSC3=NC2=O)c(C)n1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A11 compound treatment 0.214 -0.0175 -2.41 0.219 -0.0126 -1.82 -2.9958 -0.9905 3118098 ChemDiv3_005291 Cc1ccc(O)c(c1)C(CC(=O)NCC2(CCOCC2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A12 compound treatment 0.248 0.0165 2.28 0.249 0.0174 2.51 3.3898 0.9989 3025486 ChemDiv3_005292 Cc1ccc2NC(C3CCOC3c2c1)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A13 compound treatment 0.261 0.0295 4.08 0.263 0.0314 4.53 6.0896 0.9986 1685959 ChemDiv3_005293 CCCCN(C)c1nc(CC)c2COC(C)(C)Cc2c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A14 compound treatment 0.222 -0.00947 -1.31 0.227 -0.00462 -0.67 -1.3972 -0.9514 3025487 ChemDiv3_005294 Fc1ccccc1COc2ccc3c(=O)c(coc3c2)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A15 compound treatment 0.223 -0.00847 -1.17 0.222 -0.00962 -1.39 -1.8102 -0.9963 3118099 ChemDiv3_005295 CCc1nc2sc3c(SCC=C)ncnc3c2c4CCCCc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A16 compound treatment 0.209 -0.0225 -3.1 0.212 -0.0196 -2.83 -4.1992 -0.999 3118100 ChemDiv3_005296 O=C(C1CCCN(C1)C(=O)c2ccccc2)N3CCC(Cc4ccccc4)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A17 compound treatment 0.349 0.118 16.24 0.333 0.101 14.64 21.8358 0.9987 3025488 ChemDiv3_005297 CCOC(=O)c1c(N)oc2c(c3ccc(CC)cc3)c4c(C(=O)OCC)c(N)oc4cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A18 compound treatment 0.215 -0.0165 -2.27 0.218 -0.0136 -1.97 -3.0002 -0.9974 3118101 ChemDiv3_005298 CCCN1CCC(CC1)N2CCCC(C2)C(=O)N(C)CCc3ccc(OC)c(OC)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A19 compound treatment 0.273 0.0415 5.74 0.266 0.0344 4.97 7.5683 0.9974 3025489 ChemDiv3_005299 CCCCc1ccc(NCc2nc(no2)c3ccc(C)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A20 compound treatment 0.216 -0.0155 -2.14 0.217 -0.0146 -2.11 -3.0047 -1.0 3118102 ChemDiv3_005300 OC(=O)c1cccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A21 compound treatment 0.212 -0.0195 -2.69 0.213 -0.0186 -2.69 -3.804 -1.0 3025490 ChemDiv3_005301 CN1CCN(CC1)C(=O)NCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A22 compound treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 3118103 ChemDiv3_005302 CCOc1ccc2c(c1)sc3c(C)cc(=O)oc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A23 mock treatment 0.217 -0.0145 -2.0 0.222 -0.00962 -1.39 -2.3963 -0.9843 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 A24 positive control 0.215 -0.0165 -2.27 0.214 -0.0176 -2.55 -3.4088 -0.9984 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B01 compound treatment 0.298 0.0665 9.19 0.298 0.0664 9.59 13.2789 0.9998 3118104 ChemDiv3_005303 CCN(CC)c1ccc(/N=c\2/ccc3ccccc3n2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B02 compound treatment 0.227 -0.00447 -0.62 0.227 -0.00462 -0.67 -0.9087 -0.9992 3025491 ChemDiv3_005304 Cc1n[nH]c(C)c1CCCOc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B03 compound treatment 0.23 -0.00147 -0.2 0.23 -0.00162 -0.23 -0.3093 -0.9973 3118105 ChemDiv3_005305 CC1N(C)C(=O)N(OC1=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B04 compound treatment 0.239 0.00753 1.04 0.236 0.00437 0.63 1.1828 0.9714 3025492 ChemDiv3_005306 COC(=O)c1cc(on1)c2cccc(OC)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B05 compound treatment 0.294 0.0625 8.64 0.294 0.0624 9.01 12.4796 0.9998 1346624 ChemDiv3_005307 C1CCC(CC1)c2ccc3n4CCN=C5CCCc(c54)c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B06 compound treatment 0.276 0.0445 6.15 0.271 0.0394 5.69 8.3721 0.9992 1692119 ChemDiv3_005308 Cc1cccc(NC(=O)C2c3ccccc3Oc4ccccc24)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B07 compound treatment 0.227 -0.00447 -0.62 0.231 -6.25E-4 -0.09 -0.5002 -0.802 3025493 ChemDiv3_005309 COC(=O)N(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B08 compound treatment 0.235 0.00353 0.49 0.234 0.00238 0.34 0.5877 0.9851 3118106 ChemDiv3_005310 CC(Oc1ccc(Cl)cc1C)C(=O)N2CCN(CC2)c3ccccc3F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B09 compound treatment 0.338 0.107 14.72 0.339 0.107 15.51 21.3741 0.9997 1341182 ChemDiv3_005311 CC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B10 compound treatment 0.3 0.0685 9.47 0.321 0.0894 12.91 15.8235 0.9884 3025494 ChemDiv3_005312 COc1cccc(/C=C/2\CCC/C(=C/c3cccc(OC)c3OC)/C2=O)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B11 compound treatment 0.438 0.207 28.53 0.443 0.211 30.53 41.7653 0.9994 1875367 ChemDiv3_005313 CCn1c(N)c(sc1=S)C(=O)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B12 compound treatment 0.226 -0.00547 -0.76 0.229 -0.00262 -0.38 -0.8021 -0.9492 3118107 ChemDiv3_005314 CCn1c(S)nnc1c2csc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B13 compound treatment 0.265 0.0335 4.63 0.268 0.0364 5.25 6.9911 0.998 3118108 ChemDiv3_005315 Cc1ccc(c(C)c1C)S(=O)(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(C)c(C)c3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B14 compound treatment 0.23 -0.00147 -0.2 0.231 -6.25E-4 -0.09 -0.2071 -0.9337 1248039 ChemDiv3_005316 Cc1cc(NC(=O)CCC2CCCCC2)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B15 compound treatment 0.222 -0.00947 -1.31 0.225 -0.00662 -0.96 -1.6014 -0.9882 3118109 ChemDiv3_005317 Cc1ccc(cc1CNS(=O)(=O)C)c2nn(C)c(=O)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B16 compound treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 1550315 ChemDiv3_005318 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B17 compound treatment 0.229 -0.00247 -0.34 0.231 -6.25E-4 -0.09 -0.3048 -0.8646 3025495 ChemDiv3_005319 COC(=O)CCn1nc(c2ccc(Cl)cc2)c3ccccc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B18 compound treatment 0.266 0.0345 4.77 0.283 0.0514 7.42 8.6208 0.9772 1302577 ChemDiv3_005320 CCCc1ccc(CC2(CC(=O)OCC)C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B19 compound treatment 0.284 0.0525 7.26 0.281 0.0494 7.13 10.1749 1.0 3118110 ChemDiv3_005321 CC/1=NN(C(=S)\C1=C/Nc2nc(cs2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B20 compound treatment 0.229 -0.00247 -0.34 0.232 3.75E-4 0.05 -0.2027 -0.5873 1585203 ChemDiv3_005322 O=C(C1CC1)N2CCN(CC2)c3ncccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B21 compound treatment 0.268 0.0365 5.05 0.264 0.0324 4.68 6.8756 0.9993 3118111 ChemDiv3_005323 O=C(CN1C(=O)c2cccc3cccc1c23)N(Cc4ccccc4)Cc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B22 compound treatment 0.224 -0.00747 -1.03 0.226 -0.00562 -0.81 -1.3039 -0.993 3025496 ChemDiv3_005324 Cc1ccc(NCc2nnc(SCC(=O)c3ccccc3)n2CC=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B23 mock treatment 0.234 0.00253 0.35 0.235 0.00337 0.49 0.5922 0.9868 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 B24 positive control 0.231 -4.67E-4 -0.06 0.233 0.00138 0.2 0.0949 0.4542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C01 compound treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 3118112 ChemDiv3_005325 Clc1ccc(cc1)c2csc3nnc(SCC(=O)NCc4ccc5OCOc5c4)n23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C02 compound treatment 0.242 0.0105 1.46 0.233 0.00138 0.2 1.1694 0.7962 3118113 ChemDiv3_005326 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccc(cc3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C03 compound treatment 0.224 -0.00747 -1.03 0.224 -0.00762 -1.1 -1.5082 -0.9995 1863776 ChemDiv3_005327 CCOc1cc(CNC2(CC3CC4CC(C3)C2)C4)ccc1OCc5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C04 compound treatment 0.229 -0.00247 -0.34 0.228 -0.00362 -0.52 -0.6112 -0.9784 3118236 ChemDiv3_005328 CCn1c(SCc2ccc(Br)cc2)nnc1c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C05 compound treatment 0.237 0.00553 0.76 0.239 0.00737 1.07 1.2938 0.9868 1718306 ChemDiv3_005329 CC(c1ccccc1)n2c(COc3ccccc3)nc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C06 compound treatment 0.288 0.0565 7.81 0.282 0.0504 7.28 10.6678 0.9994 3025497 ChemDiv3_005330 FC(F)(F)c1nc2c(=O)oc3ccccc3c2n1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C07 compound treatment 0.232 5.33E-4 0.07 0.236 0.00437 0.63 0.499 0.7842 3118237 ChemDiv3_005331 O=C1N(CCCn2c(=O)oc3ccccc23)C(=O)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C08 compound treatment 0.297 0.0655 9.05 0.312 0.0804 11.61 14.6112 0.9924 3025498 ChemDiv3_005332 COC(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C09 compound treatment 0.288 0.0565 7.81 0.281 0.0494 7.13 10.5657 0.999 3118238 ChemDiv3_005333 Cn1nc(SCC(=O)n2c3CCCCc3c4ccccc24)sc1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C10 compound treatment 0.342 0.111 15.27 0.329 0.0974 14.07 20.7435 0.9992 3118239 ChemDiv3_005334 CC1=CN2C(=NC(=O)/C(=C\c3cc(C)n(Cc4ccccc4)c3C)/C2=N)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C11 compound treatment 0.221 -0.0105 -1.45 0.223 -0.00862 -1.25 -1.9034 -0.9972 3025499 ChemDiv3_005335 OC(=O)CCN1C(=O)SC(CC(=O)Nc2nccs2)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C12 compound treatment 0.228 -0.00347 -0.48 0.227 -0.00462 -0.67 -0.811 -0.9867 3118240 ChemDiv3_005336 COc1cccc(c1)N2C(CC=C)c3cccc(C(=O)O)c3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C13 compound treatment 0.264 0.0325 4.49 0.267 0.0354 5.11 6.7913 0.998 1674657 ChemDiv3_005337 CC1(C)Cc2c(C#N)c(NCC3CCCO3)nc(c4ccccc4)c2CO1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C14 compound treatment 0.224 -0.00747 -1.03 0.224 -0.00762 -1.1 -1.5082 -0.9995 3025500 ChemDiv3_005338 CCOC(=O)c1sc2ncn3c(nnc3c2c1C)c4ccc(C)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C15 compound treatment 0.218 -0.0135 -1.86 0.221 -0.0106 -1.53 -2.4007 -0.9954 3118241 ChemDiv3_005339 Cc1cc(Oc2ccccc2)nc(Oc3ccc(OCCOc4ccc(Br)cc4)nn3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C16 compound treatment 0.228 -0.00347 -0.48 0.229 -0.00262 -0.38 -0.6068 -0.9933 3025501 ChemDiv3_005340 COc1ccc(cc1)C(=O)N2CCCC(C2)C(=O)N3CCCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C17 compound treatment 0.238 0.00653 0.9 0.237 0.00537 0.78 1.1872 0.9972 3118242 ChemDiv3_005341 FC(F)(F)c1cccc(Cc2cn3cc(nc3s2)c4cc5ccccc5oc4=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C18 compound treatment 0.228 -0.00347 -0.48 0.227 -0.00462 -0.67 -0.811 -0.9867 3025502 ChemDiv3_005342 O=C(C1CCCN(C1)S(=O)(=O)c2ccccc2)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C19 compound treatment 0.223 -0.00847 -1.17 0.228 -0.00362 -0.52 -1.1973 -0.9343 3118243 ChemDiv3_005343 Cc1ccc(cc1)c2noc(CN3CCN(CC3)c4ccccc4F)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C20 compound treatment 0.226 -0.00547 -0.76 0.23 -0.00162 -0.23 -0.7 -0.8851 3025503 ChemDiv3_005344 Cc1ccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C21 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3118244 ChemDiv3_005345 OCCN1CCN(CC1)C(=O)NCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C22 compound treatment 0.282 0.0505 6.98 0.288 0.0564 8.14 10.6945 0.9971 3118245 ChemDiv3_005346 CCn1/c(=N\c2ccc(C)cc2)/ccc3cc(C)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C23 mock treatment 0.231 -4.67E-4 -0.06 0.233 0.00138 0.2 0.0949 0.4542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 C24 positive control 0.233 0.00153 0.21 0.235 0.00337 0.49 0.4945 0.9303 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D01 compound treatment 0.222 -0.00947 -1.31 0.223 -0.00862 -1.25 -1.8057 -0.9997 3025504 ChemDiv3_005347 OC(=O)c1cccc(Nc2nc(Nc3ccccc3)nc(n2)N4CCCC4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D02 compound treatment 0.226 -0.00547 -0.76 0.224 -0.00762 -1.1 -1.3128 -0.9831 3118246 ChemDiv3_005348 CC(C)c1ccc(OCCCN2CCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D03 compound treatment 0.22 -0.0115 -1.58 0.222 -0.00962 -1.39 -2.1032 -0.9979 1230490 ChemDiv3_005349 Cc1ccc2n3CCN(C=O)C4CCCc(c43)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D04 compound treatment 0.28 0.0485 6.7 0.284 0.0524 7.57 10.0906 0.9982 3118247 ChemDiv3_005350 CC1CN/C(=C/C(=O)/C=C/c2ccccc2)/C(=O)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D05 compound treatment 0.297 0.0655 9.05 0.308 0.0764 11.03 14.2026 0.9952 1147135 ChemDiv3_005351 CC(C)(C)c1ccc2n3CCN(CCC#N)C4CCCc(c43)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D06 compound treatment 0.343 0.112 15.41 0.342 0.11 15.94 22.169 0.9999 3025635 ChemDiv3_005352 CCc1c(C)sc(NC(=O)C2c3ccccc3Oc4ccccc24)c1C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D07 compound treatment 0.227 -0.00447 -0.62 0.228 -0.00362 -0.52 -0.8066 -0.9967 3118248 ChemDiv3_005353 CN(C(=O)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D08 compound treatment 0.229 -0.00247 -0.34 0.228 -0.00362 -0.52 -0.6112 -0.9784 3118249 ChemDiv3_005354 Cc1cc(Cl)ccc1OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D09 compound treatment 0.272 0.0405 5.6 0.272 0.0404 5.83 8.0834 0.9998 3025636 ChemDiv3_005355 OC(=O)COc1ccccc1C2Nc3ccccc3-c4nnc(SCC=C)nc4O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D10 compound treatment 0.237 0.00553 0.76 0.239 0.00737 1.07 1.2938 0.9868 3118250 ChemDiv3_005356 Cc1ccc(cc1C)c2cc(n3nc(cc3n2)C(=O)Nc4ccn(Cc5ccccc5)n4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D11 compound treatment 0.355 0.124 17.07 0.347 0.115 16.67 23.8519 0.9999 3025637 ChemDiv3_005357 Nc1c(sc(=S)n1CC=C)C(=O)NCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D12 compound treatment 0.227 -0.00447 -0.62 0.227 -0.00462 -0.67 -0.9087 -0.9992 3118251 ChemDiv3_005358 Cc1cc(C(=O)N2N=C(CC2(O)C(F)(F)F)C3CC3)c4ccccc4n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D13 compound treatment 0.313 0.0815 11.26 0.305 0.0734 10.6 15.4592 0.9995 3025638 ChemDiv3_005359 Oc1c(CC=C)cccc1/C=N/c2cccn3cc(nc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D14 compound treatment 0.22 -0.0115 -1.58 0.221 -0.0106 -1.53 -2.2054 -0.9999 1607969 ChemDiv3_005360 Cc1cc(NC(=O)C2CCCCC2C(=O)O)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D15 compound treatment 0.221 -0.0105 -1.45 0.221 -0.0106 -1.53 -2.1077 -0.9996 3118252 ChemDiv3_005361 Cc1cc(C)nc(SCc2cc(ccc2C)c3nn(C)c(=O)c4ccccc34)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D16 compound treatment 0.227 -0.00447 -0.62 0.228 -0.00362 -0.52 -0.8066 -0.9967 3025639 ChemDiv3_005362 Cc1cc(C)n(n1)C(=O)CCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D17 compound treatment 0.225 -0.00647 -0.89 0.224 -0.00762 -1.1 -1.4105 -0.9946 3118253 ChemDiv3_005363 Clc1ccc(cc1)c2nn(CCC(=O)NCCN3CCOCC3)c(=O)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D18 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 1244787 ChemDiv3_005364 Cc1cccc(N2CCN(CC2)C(=O)CCC(=O)O)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D19 compound treatment 0.266 0.0345 4.77 0.268 0.0364 5.25 7.0888 0.9988 3118254 ChemDiv3_005365 CCCc1nnc(N/C=C\2/C=C(OC2=O)c3ccccc3)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D20 compound treatment 0.273 0.0415 5.74 0.273 0.0414 5.98 8.2833 0.9998 1550669 ChemDiv3_005366 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4cc5ccccc5c(=O)o4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D21 compound treatment 0.218 -0.0135 -1.86 0.22 -0.0116 -1.68 -2.5029 -0.9987 3118255 ChemDiv3_005367 CCCC1(CNCC2(C)CNC1)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D22 compound treatment 0.223 -0.00847 -1.17 0.223 -0.00862 -1.25 -1.708 -0.9995 1138350 ChemDiv3_005368 O=C(Nc1nnn[nH]1)C2c3ccccc3Oc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D23 mock treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 D24 positive control 0.232 5.33E-4 0.07 0.234 0.00238 0.34 0.2947 0.8398 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E01 compound treatment 0.237 0.00553 0.76 0.24 0.00837 1.21 1.3959 0.9755 3118256 ChemDiv3_005369 Clc1ccc(cc1)c2csc3nnc(SCCC(=O)NCCc4ccccc4)n23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E02 compound treatment 0.223 -0.00847 -1.17 0.227 -0.00462 -0.67 -1.2995 -0.9647 3118257 ChemDiv3_005370 Fc1ccc(cc1)n2c(n[nH]c2=S)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E03 compound treatment 0.222 -0.00947 -1.31 0.225 -0.00662 -0.96 -1.6014 -0.9882 1863813 ChemDiv3_005371 COc1cccc(CNC(C)C2(CC3CC4CC(C3)C2)C4)c1OCc5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E04 compound treatment 0.223 -0.00847 -1.17 0.222 -0.00962 -1.39 -1.8102 -0.9963 3118258 ChemDiv3_005372 CC(C)Cn1c(SCc2ccccc2)nnc1c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E05 compound treatment 0.23 -0.00147 -0.2 0.234 0.00238 0.34 0.0993 0.2492 1732699 ChemDiv3_005373 CC(C)C(=O)Nc1cccc(c1)c2cn3c(C)cccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E06 compound treatment 0.223 -0.00847 -1.17 0.226 -0.00562 -0.81 -1.4016 -0.9842 3025640 ChemDiv3_005374 CC1(C)Cc2c(c3ccccc3n2c4ccccc4)C(C)(C)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E07 compound treatment 0.318 0.0865 11.95 0.315 0.0834 12.04 16.969 1.0 3118259 ChemDiv3_005375 COC(=O)/C(=C/c1ccc2OCOc2c1)/NC(=O)c3ccc(cc3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E08 compound treatment 0.283 0.0515 7.12 0.273 0.0414 5.98 9.2601 0.9962 3118260 ChemDiv3_005376 C=CCNC(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E09 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 3025641 ChemDiv3_005377 NC(=O)C1CCN(CC1)C(=O)CSc2ncccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E10 compound treatment 0.283 0.0515 7.12 0.281 0.0494 7.13 10.0773 1.0 3118393 ChemDiv3_005378 CCOc1cc(/C=C/2\C(=N)N3C(=CSC3=NC2=O)C)ccc1OCc4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E11 compound treatment 0.302 0.0705 9.74 0.304 0.0724 10.45 14.2825 0.9994 3025677 ChemDiv3_005379 O=C1CSC(=N1)Nc2nccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E12 compound treatment 0.25 0.0185 2.56 0.249 0.0174 2.51 3.5851 1.0 1523673 ChemDiv3_005380 CN1C(CC=C(C)C1c2ccccc2)c3cnc(c(C)c3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E13 compound treatment 0.253 0.0215 2.97 0.259 0.0274 3.95 4.8996 0.9902 3025678 ChemDiv3_005381 CCc1nc2sc3c(NCCc4ccccc4)ncnc3c2c5CCCCc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E14 compound treatment 0.413 0.182 25.08 0.412 0.18 26.05 36.1568 0.9998 3118394 ChemDiv3_005382 COc1ccc(cc1)c2c/c(=N\CCc3ccccc3)/c4cc(C)ccc4o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E15 compound treatment 0.223 -0.00847 -1.17 0.224 -0.00762 -1.1 -1.6059 -0.9995 1875998 ChemDiv3_005383 Cc1cc(Oc2ccc(=O)n(C)n2)nc(Oc3ccc(=O)n(C)n3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E16 compound treatment 0.223 -0.00847 -1.17 0.224 -0.00762 -1.1 -1.6059 -0.9995 3025679 ChemDiv3_005384 Clc1cccc(CN2CCCC(C2)C(=O)N3CCCCCC3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E17 compound treatment 0.231 -4.67E-4 -0.06 0.231 -6.25E-4 -0.09 -0.1094 -0.9864 3118395 ChemDiv3_005385 Clc1ccccc1Cc2cn3cc(nc3s2)c4cc5ccccc5oc4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E18 compound treatment 0.227 -0.00447 -0.62 0.231 -6.25E-4 -0.09 -0.5002 -0.802 3118396 ChemDiv3_005386 CCn1c2ccccc2c3cc(CN4CCC(CC4)N5CCCCC5)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E19 compound treatment 0.222 -0.00947 -1.31 0.223 -0.00862 -1.25 -1.8057 -0.9997 3025680 ChemDiv3_005387 O=C(NCN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E20 compound treatment 0.239 0.00753 1.04 0.241 0.00937 1.35 1.6935 0.9915 3118397 ChemDiv3_005388 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3ccc4CCc5cccc3c54 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E21 compound treatment 0.238 0.00653 0.9 0.237 0.00537 0.78 1.1872 0.9972 3025681 ChemDiv3_005389 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E22 compound treatment 0.226 -0.00547 -0.76 0.227 -0.00462 -0.67 -1.0064 -0.9981 3118398 ChemDiv3_005390 Cn1/c(=N/c2ccccc2C(=O)O)/sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E23 mock treatment 0.23 -0.00147 -0.2 0.231 -6.25E-4 -0.09 -0.2071 -0.9337 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 E24 positive control 0.233 0.00153 0.21 0.234 0.00238 0.34 0.3924 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F01 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3118399 ChemDiv3_005391 O=C(NCCN1C(=O)C2C3CC(C=C3)C2C1=O)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F02 compound treatment 0.227 -0.00447 -0.62 0.227 -0.00462 -0.67 -0.9087 -0.9992 1301199 ChemDiv3_005392 OC(=O)c1ccc(NC(CC(=O)c2ccc(Cl)cc2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F03 compound treatment 0.255 0.0235 3.25 0.255 0.0234 3.38 4.6864 0.9998 1472870 ChemDiv3_005393 CC(C)c1ccc2[nH]c3C(=O)CCCc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F04 compound treatment 0.29 0.0585 8.09 0.291 0.0594 8.58 11.7825 0.9996 3118400 ChemDiv3_005394 COC(=O)C1=C(C(c2ccc(cc2)C(=O)OC)n3nnnc3N1)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F05 compound treatment 0.247 0.0155 2.15 0.249 0.0174 2.51 3.2921 0.997 1302281 ChemDiv3_005395 Cc1ccc(NC(=S)N2CCn3c4C2CCc4c(=O)c5cc(C)ccc35)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F06 compound treatment 0.227 -0.00447 -0.62 0.229 -0.00262 -0.38 -0.7045 -0.9727 3118401 ChemDiv3_005396 COc1ccccc1N2CCN(CC2)C(=O)C3C(C4OC3C=C4)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F07 compound treatment 0.226 -0.00547 -0.76 0.229 -0.00262 -0.38 -0.8021 -0.9492 3025682 ChemDiv3_005397 C/C(=C\C(=O)Nc1ccccc1)/N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F08 compound treatment 0.242 0.0105 1.46 0.247 0.0154 2.22 2.5994 0.979 1123206 ChemDiv3_005398 O=C(CCC1CCCCC1)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F09 compound treatment 0.218 -0.0135 -1.86 0.218 -0.0136 -1.97 -2.7072 -0.9996 1399432 ChemDiv3_005399 Cc1cccc(OCC(=O)N2CCCc3ccccc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F10 compound treatment 0.22 -0.0115 -1.58 0.22 -0.0116 -1.68 -2.3075 -0.9996 3118402 ChemDiv3_005400 Cc1ccc(cc1)n2c(S)nnc2c3nn(C)cc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F11 compound treatment 0.303 0.0715 9.88 0.295 0.0634 9.15 13.4609 0.9993 3118403 ChemDiv3_005401 COc1ccc(cc1)n2c(N)c(sc2=S)c3nc4ccccc4n3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F12 compound treatment 0.225 -0.00647 -0.89 0.225 -0.00662 -0.96 -1.3084 -0.9994 3025683 ChemDiv3_005402 COc1ccc(/N=C/c2c(C)c(C#N)c3[nH]c4ccccc4n3c2=O)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F13 compound treatment 0.267 0.0355 4.91 0.264 0.0324 4.68 6.7779 0.9997 3118404 ChemDiv3_005403 Oc1ccc2ccccc2c1/C=N/c3cccn4cc(nc34)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F14 compound treatment 0.213 -0.0185 -2.55 0.213 -0.0186 -2.69 -3.7063 -0.9996 1691290 ChemDiv3_005404 COc1cccc(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccc(C)n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F15 compound treatment 0.216 -0.0155 -2.14 0.217 -0.0146 -2.11 -3.0047 -1.0 3025684 ChemDiv3_005405 CCN(CC)C(=O)CCn1nc(c2ccc(C)cc2)c3ccccc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F16 compound treatment 0.223 -0.00847 -1.17 0.224 -0.00762 -1.1 -1.6059 -0.9995 1623425 ChemDiv3_005406 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccncc3)cc2)nc(C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F17 compound treatment 0.231 -4.67E-4 -0.06 0.232 3.75E-4 0.05 -0.0073 -0.0865 3025685 ChemDiv3_005407 Clc1ccc(cc1)c2nn(CCC(=O)N3CCN(Cc4ccccc4)CC3)c(=O)c5ccccc25 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F18 compound treatment 0.229 -0.00247 -0.34 0.229 -0.00262 -0.38 -0.5091 -0.9986 1377550 ChemDiv3_005408 CCOC(=O)c1c(NC(=O)c2cc3ccccc3c(=O)o2)sc4CCCCCCc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F19 compound treatment 0.225 -0.00647 -0.89 0.225 -0.00662 -0.96 -1.3084 -0.9994 3025686 ChemDiv3_005409 CCOc1ccc(cc1)S(=O)(=O)/N=C(\N)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F20 compound treatment 0.229 -0.00247 -0.34 0.225 -0.00662 -0.96 -0.9176 -0.9033 1483573 ChemDiv3_005410 O=C(Nc1ccc2OCOc2c1)C3c4ccccc4Oc5ccccc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F21 compound treatment 0.219 -0.0125 -1.72 0.222 -0.00962 -1.39 -2.2009 -0.9944 3025687 ChemDiv3_005411 C(c1ccccc1)[n+]2cccc(c2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F22 compound treatment 0.333 0.102 14.03 0.332 0.1 14.5 20.1707 0.9999 3118405 ChemDiv3_005412 COc1ccc(CC(=O)Nc2ccc3c(cc(=O)oc3c2)C(F)(F)F)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F23 mock treatment 0.231 -4.67E-4 -0.06 0.232 3.75E-4 0.05 -0.0073 -0.0865 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 F24 positive control 0.234 0.00253 0.35 0.234 0.00238 0.34 0.4901 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G01 compound treatment 0.234 0.00253 0.35 0.245 0.0134 1.93 1.6136 0.8218 1863502 ChemDiv3_005413 CCOc1cc(CNc2ccc(cc2)N3CCOCC3)ccc1OCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G02 compound treatment 0.228 -0.00347 -0.48 0.228 -0.00362 -0.52 -0.7089 -0.999 3025688 ChemDiv3_005414 COc1ccccc1n2c(n[nH]c2=S)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G03 compound treatment 0.234 0.00253 0.35 0.236 0.00437 0.63 0.6943 0.9612 1863847 ChemDiv3_005415 CCOc1cc(CNc2ccc(NC(=O)CC)cc2)ccc1OCc3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G04 compound treatment 0.224 -0.00747 -1.03 0.224 -0.00762 -1.1 -1.5082 -0.9995 3025689 ChemDiv3_005416 COc1ccc(cc1)C2(CNC(=S)Nc3ccccc3)CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G05 compound treatment 0.305 0.0735 10.16 0.319 0.0874 12.62 16.1076 0.9942 1476189 ChemDiv3_005417 CCOc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)c3cn4cccc(C)c4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G06 compound treatment 0.251 0.0195 2.7 0.25 0.0184 2.65 3.785 1.0 3025690 ChemDiv3_005418 CC(C)CCn1c(=O)n(CC(C)C)c2[nH]c(S)nc2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G07 compound treatment 0.306 0.0745 10.3 0.307 0.0754 10.89 14.9797 0.9996 3118406 ChemDiv3_005419 CNC(=O)/C(=C\c1ccc2OCOc2c1)/NC(=O)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G08 compound treatment 0.258 0.0265 3.67 0.253 0.0214 3.09 4.7752 0.9964 1861617 ChemDiv3_005420 O=C(Nc1ccccc1N2CCCC2)c3cccc(OCc4ccccc4)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G09 compound treatment 0.221 -0.0105 -1.45 0.221 -0.0106 -1.53 -2.1077 -0.9996 3118407 ChemDiv3_005421 Cn1c(=O)n(C)c2ncn(CC/N=C/3\CCCN3)c2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G10 compound treatment 0.266 0.0345 4.77 0.263 0.0314 4.53 6.5781 0.9997 3025733 ChemDiv3_005422 CCN(CC)Cn1nc2-c3ccccc3-c4cccc(c1=O)c42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G11 compound treatment 0.219 -0.0125 -1.72 0.221 -0.0106 -1.53 -2.3031 -0.9983 3118408 ChemDiv3_005423 FC(F)(F)c1cccc(NC(=O)CC2SC(=O)NC2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G12 compound treatment 0.224 -0.00747 -1.03 0.224 -0.00762 -1.1 -1.5082 -0.9995 1400276 ChemDiv3_005424 COC(=O)CN(c1cccc2ccccc12)S(=O)(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G13 compound treatment 0.243 0.0115 1.59 0.238 0.00637 0.92 1.7778 0.966 1177986 ChemDiv3_005425 CCCC(=O)N1CCN(CC1)c2nc(Cc3ccccc3)c4COC(C)(C)Cc4c2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G14 compound treatment 0.333 0.102 14.03 0.337 0.105 15.22 20.6814 0.9992 3118530 ChemDiv3_005426 COc1ccc(cc1)c2c/c(=N/c3ccc(O)cc3)/c4cc(C)ccc4o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G15 compound treatment 0.221 -0.0105 -1.45 0.222 -0.00962 -1.39 -2.0055 -0.9998 3025734 ChemDiv3_005427 COc1cc(C)nc(SCC(=O)N)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G16 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 3118531 ChemDiv3_005428 COc1ccc(CCN(C)C(=O)C2CCCN(Cc3ccc(OC)c(OC)c3)C2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G17 compound treatment 0.257 0.0255 3.53 0.259 0.0274 3.95 5.2903 0.9984 3118532 ChemDiv3_005429 Cc1ccc2n(CC(O)CN3C(=O)CNC3=O)c4C(=O)CCCc4c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G18 compound treatment 0.248 0.0165 2.28 0.248 0.0164 2.37 3.2876 0.9998 1912397 ChemDiv3_005430 CCOC(=O)/C=C(\C)/Sc1cc(=O)oc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G19 compound treatment 0.226 -0.00547 -0.76 0.226 -0.00562 -0.81 -1.1086 -0.9993 3025735 ChemDiv3_005431 CC(NC(=O)Nc1ccccn1)N2C(=O)C3C4CC(C=C4)C3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G20 compound treatment 0.289 0.0575 7.95 0.273 0.0414 5.98 9.8463 0.9901 3118533 ChemDiv3_005432 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3nc(cs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G21 compound treatment 0.229 -0.00247 -0.34 0.233 0.00138 0.2 -0.1005 -0.2549 3025736 ChemDiv3_005433 Clc1ccc(OCC(=O)NCCC2(CC3CC4CC(C3)C2)C4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G22 compound treatment 0.274 0.0425 5.88 0.274 0.0424 6.12 8.4831 0.9998 3118534 ChemDiv3_005434 CCOc1ccc(/N=c\2/ccc3ccccc3n2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G23 mock treatment 0.229 -0.00247 -0.34 0.231 -6.25E-4 -0.09 -0.3048 -0.8646 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 G24 positive control 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H01 compound treatment 0.225 -0.00647 -0.89 0.227 -0.00462 -0.67 -1.1041 -0.9897 3118535 ChemDiv3_005435 O=C(NCCN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H02 compound treatment 0.3 0.0685 9.47 0.313 0.0814 11.75 15.0064 0.9942 3025737 ChemDiv3_005436 Clc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H03 compound treatment 0.228 -0.00347 -0.48 0.229 -0.00262 -0.38 -0.6068 -0.9933 1915152 ChemDiv3_005437 ON(C(=O)Nc1ccccc1)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H04 compound treatment 0.237 0.00553 0.76 0.24 0.00837 1.21 1.3959 0.9755 1394020 ChemDiv3_005438 CCOC(=O)c1c(C)nsc1Nc2cc(C)ccc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H05 compound treatment 0.315 0.0835 11.54 0.321 0.0894 12.91 17.2888 0.9984 1417285 ChemDiv3_005439 Cc1ccc2n(CCN(Cc3ccccc3)Cc4ccccc4)c5C(=O)CCCc5c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H06 compound treatment 0.253 0.0215 2.97 0.256 0.0244 3.52 4.5932 0.9965 3118536 ChemDiv3_005440 Clc1ccc(cc1)c2csc(NC(=O)C3c4ccccc4Oc5ccccc35)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H07 compound treatment 0.224 -0.00747 -1.03 0.223 -0.00862 -1.25 -1.6103 -0.9956 3025738 ChemDiv3_005441 CN(C(=O)c1ccccc1)c2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H08 compound treatment 0.234 0.00253 0.35 0.232 3.75E-4 0.05 0.2858 0.8069 1234713 ChemDiv3_005442 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3ccncc3)cc2)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H09 compound treatment 0.223 -0.00847 -1.17 0.221 -0.0106 -1.53 -1.9123 -0.991 3025739 ChemDiv3_005443 Clc1ccccc1OCC(=O)N2CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H10 compound treatment 0.22 -0.0115 -1.58 0.221 -0.0106 -1.53 -2.2054 -0.9999 1454824 ChemDiv3_005444 Cc1ccc2nc3CCC(Cc3c(C(=O)O)c2c1)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H11 compound treatment 0.289 0.0575 7.95 0.274 0.0424 6.12 9.9484 0.9917 3025740 ChemDiv3_005445 COc1ccccc1/C=C/C2N3C(=O)CCSC3=NC(=C2C(=O)OCC(C)C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H12 compound treatment 0.34 0.109 14.99 0.32 0.0884 12.77 19.6288 0.9968 3118537 ChemDiv3_005446 Fc1cccc(c1)C2=N/C(=C\C=C\c3ccccc3)/C(=O)N2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H13 compound treatment 0.226 -0.00547 -0.76 0.226 -0.00562 -0.81 -1.1086 -0.9993 1015846 ChemDiv3_005447 O=S(=O)(N1CCCN(CC1)S(=O)(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H14 compound treatment 0.248 0.0165 2.28 0.244 0.0124 1.79 2.8791 0.9926 1377150 ChemDiv3_005448 O=C(Nc1ccccc1)c2cc3ccccc3c(=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H15 compound treatment 0.311 0.0795 10.99 0.319 0.0874 12.62 16.6938 0.9976 3118538 ChemDiv3_005449 Cc1ccc(cc1)c2nn(CCC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H16 compound treatment 0.223 -0.00847 -1.17 0.224 -0.00762 -1.1 -1.6059 -0.9995 1382411 ChemDiv3_005450 OC(=O)CCC(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H17 compound treatment 0.226 -0.00547 -0.76 0.224 -0.00762 -1.1 -1.3128 -0.9831 3118539 ChemDiv3_005451 CCCNC(=O)Cn1c(=O)n(C)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H18 compound treatment 0.267 0.0355 4.91 0.274 0.0424 6.12 7.7993 0.994 1714411 ChemDiv3_005452 COc1ccc(CCNC(=O)c2cc3ccccc3c(=O)o2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H19 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 3118540 ChemDiv3_005453 CN(C)/C(=N\S(=O)(=O)c1ccc(F)cc1)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H20 compound treatment 0.222 -0.00947 -1.31 0.222 -0.00962 -1.39 -1.9079 -0.9995 1880109 ChemDiv3_005454 CC1CN(C(C)CN1C(=O)C2CCCCC2)C(=O)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H21 compound treatment 0.224 -0.00747 -1.03 0.226 -0.00562 -0.81 -1.3039 -0.993 3025782 ChemDiv3_005455 COc1ccc(CCNC(=O)CC(c2ccccc2)c3cccc(C)c3O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H22 compound treatment 0.289 0.0575 7.95 0.292 0.0604 8.72 11.7869 0.9989 3025741 ChemDiv3_005456 FC(F)(F)C(=O)N1C(C2=C(CC(CC2=O)c3ccco3)Nc4ccccc14)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H23 mock treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 H24 positive control 0.233 0.00153 0.21 0.235 0.00337 0.49 0.4945 0.9303 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I01 compound treatment 0.227 -0.00447 -0.62 0.23 -0.00162 -0.23 -0.6023 -0.9123 3118541 ChemDiv3_005457 Cc1ccc(CNc2ccc(N3CCOCC3)c(Cl)c2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I02 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3118542 ChemDiv3_005458 COCCn1c(n[nH]c1=S)c2ccc(cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I03 compound treatment 0.232 5.33E-4 0.07 0.235 0.00337 0.49 0.3968 0.8048 1863874 ChemDiv3_005459 Cn1nnc(NCc2cc(Br)ccc2OCc3ccccc3F)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I04 compound treatment 0.265 0.0335 4.63 0.269 0.0374 5.4 7.0932 0.9971 1566392 ChemDiv3_005460 CCOC(=O)c1ccc(Nc2cc(C)nc(C)c2C(=O)OCC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I05 compound treatment 0.335 0.104 14.3 0.313 0.0814 11.75 18.4254 0.9952 1351464 ChemDiv3_005461 Cc1cccn2cc(nc12)c3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I06 compound treatment 0.298 0.0665 9.19 0.304 0.0724 10.45 13.8918 0.9979 3118543 ChemDiv3_005462 CCOc1ccc(Br)cc1C2C(=C(N)Oc3cc(ccc23)N(C)C)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I07 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 1132528 ChemDiv3_005463 OC(=O)c1ccccc1NC(=O)c2ccc(CN3CCOCC3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I08 compound treatment 0.256 0.0245 3.39 0.257 0.0254 3.67 4.9884 0.9992 3025742 ChemDiv3_005464 CC(=O)N1N=C(CC1c2cccs2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I09 compound treatment 0.369 0.138 19.0 0.373 0.141 20.42 27.8751 0.9994 3118544 ChemDiv3_005465 C(Cn1c2ccccc2c3nc4ccccc4nc13)N5CCOCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I10 compound treatment 0.313 0.0815 11.26 0.305 0.0734 10.6 15.4592 0.9995 3025743 ChemDiv3_005466 CN1C(c2ccccc2)n3c(nc4ccccc34)-c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I11 compound treatment 0.241 0.00953 1.32 0.239 0.00737 1.07 1.6846 0.9945 1431675 ChemDiv3_005467 Clc1ccccc1C2N(Cc3ccccc3)CCN2Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I12 compound treatment 0.265 0.0335 4.63 0.263 0.0314 4.53 6.4804 0.9999 3118545 ChemDiv3_005468 Brc1c(cnn(c2ccccc2)c1=O)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I13 compound treatment 0.227 -0.00447 -0.62 0.231 -6.25E-4 -0.09 -0.5002 -0.802 3025783 ChemDiv3_005469 CCc1nc(Cl)c(C#N)c2CCCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I14 compound treatment 0.295 0.0635 8.78 0.289 0.0574 8.29 12.0666 0.9996 1304796 ChemDiv3_005470 Cc1ccc(SC2=C(N3CCOCC3)C(=O)N(C2=O)c4cc(C)cc(C)c4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I15 compound treatment 0.316 0.0845 11.68 0.314 0.0824 11.9 16.6715 1.0 3118546 ChemDiv3_005471 COc1ccc(/C=C(/NC(=O)c2ccco2)\C(=O)N3CCCC3=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I16 compound treatment 0.22 -0.0115 -1.58 0.221 -0.0106 -1.53 -2.2054 -0.9999 3025784 ChemDiv3_005472 Fc1ccccc1CN2CCCC(C2)C(=O)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I17 compound treatment 0.367 0.136 18.72 0.362 0.13 18.83 26.5562 1.0 3118547 ChemDiv3_005473 COc1ccc(cc1)C2NN=C3C2CCc4c3[nH]c5ccc(C)cc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I18 compound treatment 0.242 0.0105 1.46 0.243 0.0114 1.64 2.1908 0.9982 1436055 ChemDiv3_005474 Oc1c(Sc2ccccc2)c(=O)oc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I19 compound treatment 0.221 -0.0105 -1.45 0.223 -0.00862 -1.25 -1.9034 -0.9972 1124479 ChemDiv3_005475 Cc1ccc(cc1)S(=O)(=O)N2CC3CCC2C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I20 compound treatment 0.24 0.00853 1.18 0.231 -6.25E-4 -0.09 0.7698 0.6511 3118548 ChemDiv3_005476 COc1ccc(CN(C(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c4ccccc4O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I21 compound treatment 0.239 0.00753 1.04 0.253 0.0214 3.09 2.9191 0.8959 3025785 ChemDiv3_005477 CC(C)c1ccc(C)cc1OCC(=O)NCCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I22 compound treatment 0.248 0.0165 2.28 0.255 0.0234 3.38 4.0026 0.9819 3118549 ChemDiv3_005478 Cn1/c(=N/c2ccccc2C(=O)O)/ccc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I23 mock treatment 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 I24 positive control 0.234 0.00253 0.35 0.237 0.00537 0.78 0.7965 0.9352 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J01 compound treatment 0.229 -0.00247 -0.34 0.229 -0.00262 -0.38 -0.5091 -0.9986 3118550 ChemDiv3_005479 O=C(NCCN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J02 compound treatment 0.23 -0.00147 -0.2 0.231 -6.25E-4 -0.09 -0.2071 -0.9337 1252670 ChemDiv3_005480 CCOc1ccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J03 compound treatment 0.227 -0.00447 -0.62 0.229 -0.00262 -0.38 -0.7045 -0.9727 1661781 ChemDiv3_005481 CCc1ccc(cc1)C(=O)c2cncc(Br)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J04 compound treatment 0.268 0.0365 5.05 0.265 0.0334 4.82 6.9777 0.9997 1297371 ChemDiv3_005482 OC(=O)c1sc2ccccc2c1Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J05 compound treatment 0.229 -0.00247 -0.34 0.229 -0.00262 -0.38 -0.5091 -0.9986 817062 ChemDiv3_005483 OC(=O)Cc1ccc(O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J06 compound treatment 0.228 -0.00347 -0.48 0.229 -0.00262 -0.38 -0.6068 -0.9933 3118675 ChemDiv3_005484 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3nc(cs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J07 compound treatment 0.229 -0.00247 -0.34 0.23 -0.00162 -0.23 -0.4069 -0.9834 1661374 ChemDiv3_005485 CN(C)C1(CCCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J08 compound treatment 0.316 0.0845 11.68 0.323 0.0914 13.2 17.5908 0.9981 1119745 ChemDiv3_005486 CCOC(=O)c1c(NC(=O)c2ccn(CC)n2)sc3CCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J09 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 3025786 ChemDiv3_005487 Clc1ccc(/C=C/C(=O)NCCCn2ccnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J10 compound treatment 0.221 -0.0105 -1.45 0.221 -0.0106 -1.53 -2.1077 -0.9996 3118676 ChemDiv3_005488 CCOc1ccc(cc1)n2c(S)nnc2c3nn(C)cc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J11 compound treatment 0.422 0.191 26.32 0.415 0.183 26.49 37.3424 1.0 3118677 ChemDiv3_005489 CN(C)c1ccc(cc1)C2Nc3sc4CCCCc4c3C(=O)N2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J12 compound treatment 0.246 0.0145 2.01 0.244 0.0124 1.79 2.6837 0.9983 1628099 ChemDiv3_005490 O=C(Nc1ccc2OCOc2c1)c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J13 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 3118678 ChemDiv3_005491 CCOC(=O)C1=C(C)N(C)C2(C)CC1c3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J14 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 1258498 ChemDiv3_005492 CN(C)c1ccc(NC(=O)c2ccoc2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J15 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3118679 ChemDiv3_005493 COC(=O)CCn1nc(c2ccc(C)cc2)c3ccccc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J16 compound treatment 0.224 -0.00747 -1.03 0.227 -0.00462 -0.67 -1.2018 -0.9779 1151532 ChemDiv3_005494 COc1ccc(CC(=O)N2CCc3ccccc3C2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J17 compound treatment 0.227 -0.00447 -0.62 0.227 -0.00462 -0.67 -0.9087 -0.9992 3118680 ChemDiv3_005495 OC(=O)c1ccc(cc1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J18 compound treatment 0.225 -0.00647 -0.89 0.23 -0.00162 -0.23 -0.7977 -0.8636 1879815 ChemDiv3_005496 CCOc1ccccc1C(=O)N2CC(C)N(CC2C)C(=O)c3ccccc3OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J19 compound treatment 0.228 -0.00347 -0.48 0.231 -6.25E-4 -0.09 -0.4025 -0.8259 3025787 ChemDiv3_005497 Cc1ccccc1S(=O)(=O)/N=C(\N)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J20 compound treatment 0.226 -0.00547 -0.76 0.227 -0.00462 -0.67 -1.0064 -0.9981 3118681 ChemDiv3_005498 OC(=O)C1CC=CCC1C(=O)N2CCN(C/C=C/c3ccccc3)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J21 compound treatment 0.261 0.0295 4.08 0.254 0.0224 3.23 5.1704 0.9933 3025788 ChemDiv3_005499 COc1ccc(CCNC(=O)CC(c2ccccc2)c3cc(Br)ccc3O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J22 compound treatment 0.22 -0.0115 -1.58 0.222 -0.00962 -1.39 -2.1032 -0.9979 1480862 ChemDiv3_005500 O=C(CCc1ccccc1)N2CCCN(CC2)C(=O)CCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J23 mock treatment 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 J24 positive control 0.235 0.00353 0.49 0.234 0.00238 0.34 0.5877 0.9851 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K01 compound treatment 0.227 -0.00447 -0.62 0.23 -0.00162 -0.23 -0.6023 -0.9123 1863608 ChemDiv3_005501 C(Nn1cnnc1)c2cccc(OCc3ccccc3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K02 compound treatment 0.24 0.00853 1.18 0.243 0.0114 1.64 1.9954 0.9867 3118682 ChemDiv3_005502 CC(C)Cn1c(n[nH]c1=S)c2ccncc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K03 compound treatment 0.23 -0.00147 -0.2 0.234 0.00238 0.34 0.0993 0.2492 3118683 ChemDiv3_005503 COc1cccc(CC2CC(=O)N(C2=O)c3ccc4c(C)cc(=O)oc4c3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K04 compound treatment 0.254 0.0225 3.11 0.258 0.0264 3.81 4.8951 0.995 1788155 ChemDiv3_005504 O=C(OCc1ccccc1)N2CN(Cc3ccccc3)Cc4c2oc5ccccc5c4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K05 compound treatment 0.276 0.0445 6.15 0.275 0.0434 6.27 8.7806 1.0 1500365 ChemDiv3_005505 Cc1ccccc1C(=O)Nc2cccc(c2)c3cn4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K06 compound treatment 0.253 0.0215 2.97 0.256 0.0244 3.52 4.5932 0.9965 3025789 ChemDiv3_005506 CCc1ccc(cc1)C2C(=C(N)Oc3cc4OCOc4cc23)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K07 compound treatment 0.217 -0.0145 -2.0 0.217 -0.0146 -2.11 -2.907 -0.9996 1203882 ChemDiv3_005507 O=C(N1CCCCCC1)c2ccc(CN3CCc4ccccc4C3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K08 compound treatment 0.226 -0.00547 -0.76 0.228 -0.00362 -0.52 -0.9043 -0.984 3118684 ChemDiv3_005508 CC(=O)N1N=C(CC1c2cc3cc4OCOc4cc3nc2Cl)c5ccc(C)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K09 compound treatment 0.282 0.0505 6.98 0.275 0.0434 6.27 9.3667 0.9985 3025791 ChemDiv3_005509 CC(Cc1ccccc1)NC(=O)CC(c2ccccc2)c3cc(Br)ccc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K10 compound treatment 0.316 0.0845 11.68 0.316 0.0844 12.19 16.8758 0.9998 1541015 ChemDiv3_005510 N1C(c2ccncc2)n3c(nc4ccccc34)-c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K11 compound treatment 0.231 -4.67E-4 -0.06 0.231 -6.25E-4 -0.09 -0.1094 -0.9864 3118685 ChemDiv3_005511 Cc1ccc(cc1)N(CC(=O)NC(c2ccccc2)c3ccccc3)S(=O)(=O)N4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K12 compound treatment 0.261 0.0295 4.08 0.259 0.0274 3.95 5.6811 0.9999 3118686 ChemDiv3_005512 CCC(C)OC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K13 compound treatment 0.225 -0.00647 -0.89 0.228 -0.00362 -0.52 -1.002 -0.9676 1344366 ChemDiv3_005513 CCc1nc(N2CCCCC2)c(C#N)c3CCCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K14 compound treatment 0.239 0.00753 1.04 0.241 0.00937 1.35 1.6935 0.9915 1538233 ChemDiv3_005514 CCc1ccccc1OCC(=O)Nc2ccc(cc2)S(=O)(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K15 compound treatment 0.216 -0.0155 -2.14 0.218 -0.0136 -1.97 -2.9025 -0.9992 3118687 ChemDiv3_005515 CCc1ccc(cc1)C2=CC(=O)C=CC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K16 compound treatment 0.226 -0.00547 -0.76 0.227 -0.00462 -0.67 -1.0064 -0.9981 3118688 ChemDiv3_005516 O=C(C1CCCN(Cc2ccco2)C1)N3CCCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K17 compound treatment 0.329 0.0975 13.47 0.302 0.0704 10.17 16.7158 0.9903 3025829 ChemDiv3_005517 Cc1ccc2[nH]c3C4=NNC(C4CCc3c2c1)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K18 compound treatment 0.271 0.0395 5.46 0.272 0.0404 5.83 7.9858 0.9995 3118689 ChemDiv3_005518 COC(=O)C1=C(N)OC2=C(C1c3ccc(OCc4ccccc4F)cc3)C(=O)CCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K19 compound treatment 0.225 -0.00647 -0.89 0.227 -0.00462 -0.67 -1.1041 -0.9897 3025830 ChemDiv3_005519 Cc1ccc(cc1)S(=O)(=O)N2CC3CC2C=C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K20 compound treatment 0.223 -0.00847 -1.17 0.224 -0.00762 -1.1 -1.6059 -0.9995 3118690 ChemDiv3_005520 CC(C)CNC(=O)CCN1C(=O)c2ccccc2S1(=O)=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K21 compound treatment 0.236 0.00453 0.63 0.238 0.00637 0.92 1.094 0.9824 1184424 ChemDiv3_005521 O=C(NCCC1(CC2CC3CC(C2)C1)C3)C4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K22 compound treatment 0.276 0.0445 6.15 0.274 0.0424 6.12 8.6785 1.0 3025831 ChemDiv3_005522 Cn1/c(=N\c2ccc(cc2)N3CCOCC3)/ccc4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K23 mock treatment 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 K24 positive control 0.233 0.00153 0.21 0.234 0.00238 0.34 0.3924 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L01 compound treatment 0.215 -0.0165 -2.27 0.217 -0.0146 -2.11 -3.1024 -0.9993 3118691 ChemDiv3_005523 O=C(Nc1nncs1)Nc2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L02 compound treatment 0.223 -0.00847 -1.17 0.225 -0.00662 -0.96 -1.5038 -0.995 3025832 ChemDiv3_005524 COC(=O)C1CCN(CC1)C(=O)Cc2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L03 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3118692 ChemDiv3_005525 CC1ON(C(=O)NC1=O)c2ccc(Br)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L04 compound treatment 0.26 0.0285 3.94 0.252 0.0204 2.94 4.8684 0.9896 3025833 ChemDiv3_005526 CCc1cccc(NC(=O)C2c3ccccc3Oc4ccccc24)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L05 compound treatment 0.26 0.0285 3.94 0.264 0.0324 4.68 6.0941 0.9964 3118693 ChemDiv3_005527 CC(C)COc1ccc2c(c1)c3CCCc4[n+](C)ccn2c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L06 compound treatment 0.263 0.0315 4.36 0.261 0.0294 4.24 6.0807 0.9999 3118694 ChemDiv3_005528 CCN(CC)c1ccc(NC(=O)C2c3ccccc3Oc4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L07 compound treatment 0.218 -0.0135 -1.86 0.22 -0.0116 -1.68 -2.5029 -0.9987 1478251 ChemDiv3_005529 CN(C)c1ccc(cc1)C(N2CCOCC2)c3nnnn3CCOC(=O)Nc4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L08 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 1142691 ChemDiv3_005530 CCOC(=O)c1cc(NC(=O)C2C(C3OC2C=C3)C(=O)O)cc(c1)C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L09 compound treatment 0.222 -0.00947 -1.31 0.22 -0.0116 -1.68 -2.1121 -0.9924 3118834 ChemDiv3_005531 CC(C)(C)c1ccc(/C=C/C(=O)NCCCn2ccnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L10 compound treatment 0.215 -0.0165 -2.27 0.216 -0.0156 -2.26 -3.2045 -1.0 3025834 ChemDiv3_005532 CCn1c(S)nnc1c2cc(C)n(C)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L11 compound treatment 0.221 -0.0105 -1.45 0.227 -0.00462 -0.67 -1.4949 -0.9385 3025835 ChemDiv3_005533 CC1(C)Cc2c(CO1)sc3nc(CCCc4ccccc4)n(N)c(=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L12 compound treatment 0.259 0.0275 3.8 0.261 0.0294 4.24 5.69 0.9985 3118835 ChemDiv3_005534 Cc1ccsc1C2C(=C(N)Oc3[nH]c(nc23)c4ccccc4)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L13 compound treatment 0.222 -0.00947 -1.31 0.227 -0.00462 -0.67 -1.3972 -0.9514 3118836 ChemDiv3_005535 COc1ccc(NC(=O)N2CCN(C/C=C/c3ccccc3)CC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L14 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 1459940 ChemDiv3_005536 O=C(NCC1CCCO1)C2c3ccccc3Oc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L15 compound treatment 0.222 -0.00947 -1.31 0.221 -0.0106 -1.53 -2.01 -0.9968 3118837 ChemDiv3_005537 Cc1ccc(cc1)c2nn(CCC(=O)N3CCCC3)c(=O)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L16 compound treatment 0.224 -0.00747 -1.03 0.226 -0.00562 -0.81 -1.3039 -0.993 1569367 ChemDiv3_005538 OC(=O)C1CCCCC1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L17 compound treatment 0.226 -0.00547 -0.76 0.227 -0.00462 -0.67 -1.0064 -0.9981 3025836 ChemDiv3_005539 Fc1ccccc1c2nc(no2)c3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L18 compound treatment 0.223 -0.00847 -1.17 0.222 -0.00962 -1.39 -1.8102 -0.9963 1310245 ChemDiv3_005540 OC(=O)C1C(C2CC1C=C2)C(=O)NCc3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L19 compound treatment 0.223 -0.00847 -1.17 0.226 -0.00562 -0.81 -1.4016 -0.9842 3118838 ChemDiv3_005541 CC(C)(C)N/C(=N\S(=O)(=O)c1ccc(Br)cc1)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L20 compound treatment 0.249 0.0175 2.42 0.25 0.0184 2.65 3.5896 0.999 1202411 ChemDiv3_005542 COC(=O)CN(C(=O)c1cc2ccccc2oc1=O)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L21 compound treatment 0.216 -0.0155 -2.14 0.219 -0.0126 -1.82 -2.8004 -0.9969 3025837 ChemDiv3_005543 COc1ccc(cc1OC)C2(CCCC2)C(=O)NCc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L22 compound treatment 0.222 -0.00947 -1.31 0.223 -0.00862 -1.25 -1.8057 -0.9997 3118839 ChemDiv3_005544 OC(=O)C1C(C2CCC1O2)C(=O)N3CCN(C/C=C/c4ccccc4)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L23 mock treatment 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 L24 positive control 0.232 5.33E-4 0.07 0.234 0.00238 0.34 0.2947 0.8398 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M01 compound treatment 0.246 0.0145 2.01 0.247 0.0154 2.22 2.9901 0.9987 1863694 ChemDiv3_005545 CCCCC(=O)Nc1ccc(NCc2ccc(C)s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M02 compound treatment 0.26 0.0285 3.94 0.259 0.0274 3.95 5.5834 1.0 1844088 ChemDiv3_005546 COc1ccccc1n2c(n[nH]c2=S)c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M03 compound treatment 0.343 0.112 15.41 0.345 0.113 16.38 22.4754 0.9995 3118840 ChemDiv3_005547 CCOC(=O)C(C)N1C(=O)S/C(=C/c2ccc(o2)c3ccccc3C(=O)O)/C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M04 compound treatment 0.25 0.0185 2.56 0.255 0.0234 3.38 4.198 0.9907 3025838 ChemDiv3_005548 CCOC(=O)Nc1oc2ccccc2c(=O)c1CN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M05 compound treatment 0.249 0.0175 2.42 0.248 0.0164 2.37 3.3853 0.9999 3118841 ChemDiv3_005549 CN(C)c1oc(nc1S(=O)(=O)c2ccc(C)cc2)c3ccccc3Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M06 compound treatment 0.26 0.0285 3.94 0.254 0.0224 3.23 5.0727 0.9951 3118842 ChemDiv3_005550 CCN(CC)C(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M07 compound treatment 0.25 0.0185 2.56 0.248 0.0164 2.37 3.483 0.9992 3025839 ChemDiv3_005551 CC1=Nc2ccccc2N=C(O)C1Sc3nc4ccccc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M08 compound treatment 0.256 0.0245 3.39 0.274 0.0424 6.12 6.7247 0.9611 1645771 ChemDiv3_005552 Cc1ccc2nc(cc(c3ccccc3)c2c1)c4ccncc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M09 compound treatment 0.251 0.0195 2.7 0.245 0.0134 1.93 3.2743 0.9866 3118843 ChemDiv3_005553 CCCN(CCC)C(=O)CC(c1ccccc1)c2cc(Br)ccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M10 compound treatment 0.324 0.0925 12.78 0.327 0.0954 13.78 18.7808 0.9993 1210079 ChemDiv3_005554 N1C(c2ccco2)n3c(nc4ccccc34)-c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M11 compound treatment 0.229 -0.00247 -0.34 0.228 -0.00362 -0.52 -0.6112 -0.9784 3118844 ChemDiv3_005555 COc1ccc(C)cc1Cn2c(nc3ccccc23)S(=O)(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M12 compound treatment 0.258 0.0265 3.67 0.251 0.0194 2.8 4.5709 0.9911 3118845 ChemDiv3_005556 CCC(C)OC(=O)COc1ccc2c(=O)c(Oc3cc(C)ccc3C)coc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M13 compound treatment 0.252 0.0205 2.84 0.255 0.0234 3.38 4.3933 0.9962 1459137 ChemDiv3_005557 CCc1nc(NCCN2CCOCC2)c(C#N)c3CCCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M14 compound treatment 0.232 5.33E-4 0.07 0.233 0.00138 0.2 0.1925 0.9089 3118846 ChemDiv3_005558 CCN(CC)C(=O)CSc1nc(O)c2c(C)cc(C)nc2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M15 compound treatment 0.299 0.0675 9.33 0.287 0.0554 8.0 12.2531 0.9971 3025063 ChemDiv3_005559 CCc1ccc(cc1)c2cc(O)cc3sc(=O)oc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M16 compound treatment 0.225 -0.00647 -0.89 0.225 -0.00662 -0.96 -1.3084 -0.9994 3118847 ChemDiv3_005560 O=C(C1CCCN(CC2CC3CC2C=C3)C1)N4CCC(Cc5ccccc5)CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M17 compound treatment 0.32 0.0885 12.23 0.322 0.0904 13.05 17.8794 0.9995 3025066 ChemDiv3_005561 Cc1ccc2n(CCC(=O)O)c3C(=O)CCCc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M18 compound treatment 0.227 -0.00447 -0.62 0.229 -0.00262 -0.38 -0.7045 -0.9727 3025068 ChemDiv3_005562 Clc1ccc(CSc2ncccn2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M19 compound treatment 0.225 -0.00647 -0.89 0.227 -0.00462 -0.67 -1.1041 -0.9897 1194966 ChemDiv3_005563 O=C(NCc1ccccc1)N2CC3CC2C=C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M20 compound treatment 0.349 0.118 16.24 0.342 0.11 15.94 22.7551 1.0 3118848 ChemDiv3_005564 COc1ccccc1C2=NC(CN2c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M21 compound treatment 0.238 0.00653 0.9 0.24 0.00837 1.21 1.4936 0.9896 1272874 ChemDiv3_005565 O=C(CCC1CCCCC1)NCCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M22 compound treatment 0.226 -0.00547 -0.76 0.224 -0.00762 -1.1 -1.3128 -0.9831 3118849 ChemDiv3_005566 OC(=O)CC[n+]1ccc(cc1)c2cc[n+](CCC(=O)O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M23 mock treatment 0.234 0.00253 0.35 0.235 0.00337 0.49 0.5922 0.9868 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 M24 positive control 0.23 -0.00147 -0.2 0.23 -0.00162 -0.23 -0.3093 -0.9973 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N01 compound treatment 0.22 -0.0115 -1.58 0.222 -0.00962 -1.39 -2.1032 -0.9979 3025074 ChemDiv3_005567 COC(=O)NCN1C(=O)C2C3CC(C=C3)C2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N02 compound treatment 0.368 0.137 18.86 0.374 0.142 20.57 27.8796 0.9991 3118850 ChemDiv3_005568 CC1(C)CC(=O)c2sc(NS(=O)(=O)C)nc2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N03 compound treatment 0.234 0.00253 0.35 0.238 0.00637 0.92 0.8986 0.9122 1577663 ChemDiv3_005569 Clc1ccc(cc1Cl)N2OCC(=O)NC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N04 compound treatment 0.219 -0.0125 -1.72 0.221 -0.0106 -1.53 -2.3031 -0.9983 3118851 ChemDiv3_005570 Clc1ncccc1C(=O)N(Cc2ccccc2)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N05 compound treatment 0.269 0.0375 5.19 0.271 0.0394 5.69 7.6882 0.9989 3118852 ChemDiv3_005571 NNC(=O)c1ccc2[nH]c3/C(=N/N)/CCCc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N06 compound treatment 0.288 0.0565 7.81 0.278 0.0464 6.7 10.2593 0.9971 3025109 ChemDiv3_005572 Cc1cc(NC(=O)/C=C/c2ccc(F)cc2)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N07 compound treatment 0.273 0.0415 5.74 0.277 0.0454 6.55 8.6918 0.9978 1467529 ChemDiv3_005573 Cc1ccc(NC2(CCCCC2)c3nnnn3CCOC(=O)Nc4ccc(Cl)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N08 compound treatment 0.603 0.372 51.33 0.598 0.366 52.92 73.7152 0.9999 3025111 ChemDiv3_005574 Cn1ccc(/C=C/2\CCC/C(=C/c3ccn(C)n3)/C2=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N09 compound treatment 0.278 0.0465 6.43 0.279 0.0474 6.84 9.3845 0.9995 1875080 ChemDiv3_005575 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C5CCCCC5)c3nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N10 compound treatment 0.262 0.0305 4.22 0.268 0.0364 5.25 6.698 0.9941 1217360 ChemDiv3_005576 COc1ccc(cc1COc2ccccc2Cl)C(=O)NCc3cc4cc(Cl)ccc4[nH]3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N11 compound treatment 0.257 0.0255 3.53 0.257 0.0254 3.67 5.0861 0.9998 3118853 ChemDiv3_005577 O=S(=O)(N1CCCCCC1)c2ccc3oc4ccc(cc4c3c2)S(=O)(=O)N5CCCCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N12 compound treatment 0.25 0.0185 2.56 0.249 0.0174 2.51 3.5851 1.0 1327882 ChemDiv3_005578 Cc1nc(C(C(C#N)C#N)c2ccccc2F)c(O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N13 compound treatment 0.233 0.00153 0.21 0.233 0.00138 0.2 0.2902 0.9995 3118854 ChemDiv3_005579 CCCC(=O)N1CCC(=N1)c2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N14 compound treatment 0.245 0.0135 1.87 0.245 0.0134 1.93 2.6881 0.9999 1390843 ChemDiv3_005580 CC(C)CN(CC(C)C)C(=O)C1c2ccccc2Oc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N15 compound treatment 0.23 -0.00147 -0.2 0.237 0.00537 0.78 0.4057 0.5056 3118980 ChemDiv3_005581 CNC(=O)COc1ccc(NC(=O)CCn2nc(c3ccc(Cl)cc3)c4ccccc4c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N16 compound treatment 0.267 0.0355 4.91 0.265 0.0334 4.82 6.88 1.0 1879391 ChemDiv3_005582 Brc1cccc(c1)c2cc(C(=O)NCc3cccnc3)c4ccccc4n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N17 compound treatment 0.227 -0.00447 -0.62 0.225 -0.00662 -0.96 -1.113 -0.9775 3118981 ChemDiv3_005583 COc1ccc(CC(=O)Nc2ccc(O)c(c2)c3nc4ccccc4o3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N18 compound treatment 0.238 0.00653 0.9 0.234 0.00238 0.34 0.8808 0.9122 1132559 ChemDiv3_005584 CC(C)OC(=O)c1c(NC(=O)c2ccc(Cn3nc(C)c(Cl)c3C)o2)sc4CCCCc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N19 compound treatment 0.272 0.0405 5.6 0.271 0.0394 5.69 7.9813 1.0 3118982 ChemDiv3_005585 Oc1ccccc1c2nnc(SCc3ccccc3)n2c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N20 compound treatment 0.266 0.0345 4.77 0.266 0.0344 4.97 6.8845 0.9998 1923004 ChemDiv3_005586 CCOC(=O)c1ccc2n(Cc3ccccc3)c(C)c(C)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N21 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3025118 ChemDiv3_005587 CCOc1ccc(NC(=O)C2(CCOCC2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N22 compound treatment 0.226 -0.00547 -0.76 0.227 -0.00462 -0.67 -1.0064 -0.9981 1121345 ChemDiv3_005588 O=C(N1CCN(CC1)c2ncccn2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N23 mock treatment 0.233 0.00153 0.21 0.232 3.75E-4 0.05 0.1881 0.8602 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 N24 positive control 0.231 -4.67E-4 -0.06 0.233 0.00138 0.2 0.0949 0.4542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O01 compound treatment 0.259 0.0275 3.8 0.26 0.0284 4.1 5.5878 0.9993 1863698 ChemDiv3_005589 CCOc1ccc(CNc2ccc(cc2)N3CCCC3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O02 compound treatment 0.227 -0.00447 -0.62 0.231 -6.25E-4 -0.09 -0.5002 -0.802 1314044 ChemDiv3_005590 CCOC(=O)c1c(C)n(c2ccc(C)cc2)c3ccc(OCC(O)CN4CCN(C)CC4)cc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O03 compound treatment 0.237 0.00553 0.76 0.235 0.00337 0.49 0.8853 0.9764 3118983 ChemDiv3_005591 Oc1ccc(cc1)n2cccc2C=C3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O04 compound treatment 0.224 -0.00747 -1.03 0.225 -0.00662 -0.96 -1.4061 -0.9993 3025165 ChemDiv3_005592 Cn1c(nc2c(=O)oc3ccccc3c12)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O05 compound treatment 0.264 0.0325 4.49 0.263 0.0314 4.53 6.3827 1.0 1629009 ChemDiv3_005593 CCOC(=O)c1ccc(NC(=O)C2C3CC(C)(Oc4ccccc34)N(C)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O06 compound treatment 0.225 -0.00647 -0.89 0.225 -0.00662 -0.96 -1.3084 -0.9994 3025167 ChemDiv3_005594 CNC(=O)CN1C(=O)c2ccccc2S1(=O)=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O07 compound treatment 0.221 -0.0105 -1.45 0.226 -0.00562 -0.81 -1.597 -0.9628 3118984 ChemDiv3_005595 OCCN1CNC(=Nc2nc3ccccc3o2)NC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O08 compound treatment 0.345 0.114 15.68 0.344 0.112 16.23 22.5686 0.9999 3118985 ChemDiv3_005596 CCOC(=O)C1C(CC(=CC1=O)c2cccs2)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O09 compound treatment 0.221 -0.0105 -1.45 0.221 -0.0106 -1.53 -2.1077 -0.9996 3025170 ChemDiv3_005597 CCCN(CCC)C(=O)CC(c1ccccc1)c2cc(C)ccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O10 compound treatment 0.294 0.0625 8.64 0.296 0.0644 9.3 12.6839 0.9993 3118986 ChemDiv3_005598 C1CC2C(O1)c3ccc4ccccc4c3NC2c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O11 compound treatment 0.226 -0.00547 -0.76 0.242 0.0104 1.5 0.5257 0.3132 1497180 ChemDiv3_005599 CCCCc1nc2sc3c(NCc4ccccc4)ncnc3c2c5CC(C)(C)OCc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O12 compound treatment 0.238 0.00653 0.9 0.239 0.00737 1.07 1.3915 0.9966 3025173 ChemDiv3_005600 CCC(C)OC(=O)COc1ccc2c(=O)c(Oc3ccccc3Cl)coc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O13 compound treatment 0.263 0.0315 4.36 0.251 0.0194 2.8 5.0593 0.9771 1391398 ChemDiv3_005601 CCc1nc(NCC(C)C)c(C#N)c2CCCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O14 compound treatment 0.264 0.0325 4.49 0.271 0.0394 5.69 7.1998 0.9932 3025175 ChemDiv3_005602 Cc1cc(C)c2c(O)nc(SCC(=O)Nc3ccccc3)nc2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O15 compound treatment 0.23 -0.00147 -0.2 0.231 -6.25E-4 -0.09 -0.2071 -0.9337 3118987 ChemDiv3_005603 Oc1cc(c2cc(ccc2Cl)C(F)(F)F)c3oc(=O)sc3c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O16 compound treatment 0.22 -0.0115 -1.58 0.221 -0.0106 -1.53 -2.2054 -0.9999 3118988 ChemDiv3_005604 COc1cc(CN2CCCC(C2)C(=O)N3CCCCCC3)ccc1OCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O17 compound treatment 0.268 0.0365 5.05 0.263 0.0314 4.53 6.7734 0.9986 3118989 ChemDiv3_005605 Cc1ccc(cc1)c2noc(CNc3ccc(Oc4ccccc4)cc3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O18 compound treatment 0.23 -0.00147 -0.2 0.232 3.75E-4 0.05 -0.105 -0.5005 3025225 ChemDiv3_005606 OC(=O)c1ccc(CSc2nc(cc(n2)C(F)(F)F)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O19 compound treatment 0.219 -0.0125 -1.72 0.219 -0.0126 -1.82 -2.5073 -0.9996 1658529 ChemDiv3_005607 OC(=O)C1(CCCCC1)NS(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O20 compound treatment 0.238 0.00653 0.9 0.236 0.00437 0.63 1.0851 0.9848 3025227 ChemDiv3_005608 O=C/1N(C(=S)S\C1=C/2\Nc3ccccc3C2=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O21 compound treatment 0.276 0.0445 6.15 0.275 0.0434 6.27 8.7806 1.0 3118990 ChemDiv3_005609 COc1ccc(cc1)C(=O)Nc2ccc3C(=O)N(CCC(=O)O)C(=O)c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O22 compound treatment 0.243 0.0115 1.59 0.248 0.0164 2.37 2.7992 0.9815 3025229 ChemDiv3_005610 Cn1/c(=N\c2cccc(O)c2)/ccc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O23 mock treatment 0.232 5.33E-4 0.07 0.232 3.75E-4 0.05 0.0904 0.9886 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 O24 positive control 0.227 -0.00447 -0.62 0.228 -0.00362 -0.52 -0.8066 -0.9967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P01 compound treatment 0.225 -0.00647 -0.89 0.227 -0.00462 -0.67 -1.1041 -0.9897 3118991 ChemDiv3_005611 COC(=O)NC(C)N1C(=O)C2C3CC(C=C3)C2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P02 compound treatment 0.244 0.0125 1.73 0.246 0.0144 2.08 2.6926 0.9959 3025231 ChemDiv3_005612 CC(C)Cn1c2ccccc2c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P03 compound treatment 0.298 0.0665 9.19 0.299 0.0674 9.73 13.3811 0.9996 1152346 ChemDiv3_005613 CC(C)c1ccc2n3CCN(CC#N)C4CCCc(c43)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P04 compound treatment 0.238 0.00653 0.9 0.242 0.0104 1.5 1.6979 0.9705 3118992 ChemDiv3_005614 O=C(Nc1ccc(Oc2ccccc2)cc1)C3c4ccccc4Oc5ccccc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P05 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 3025234 ChemDiv3_005615 CC(C)OC(=O)N(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P06 compound treatment 0.347 0.116 15.96 0.333 0.101 14.64 21.6405 0.9991 1670317 ChemDiv3_005616 COC(=O)c1c(NC(=O)C(C)Oc2ccccc2)sc3CCc4ccccc4-c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P07 compound treatment 0.246 0.0145 2.01 0.246 0.0144 2.08 2.888 0.9999 3025236 ChemDiv3_005617 FC(F)(F)c1cccc(NC(=O)C(=C2CCCCCC2)C#N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P08 compound treatment 0.307 0.0755 10.44 0.291 0.0594 8.58 13.4431 0.9953 3118993 ChemDiv3_005618 CCN1CCc2c(C1)sc3NC(NC(=O)c23)c4ccc(COc5cccc(c5)C(F)(F)F)o4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P09 compound treatment 0.317 0.0855 11.82 0.32 0.0884 12.77 17.382 0.9993 1875125 ChemDiv3_005619 CC1CCCCN1S(=O)(=O)c2ccc(NC(=O)c3oc4ccccc4c3C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P10 compound treatment 0.339 0.108 14.86 0.34 0.108 15.65 21.5739 0.9997 3118994 ChemDiv3_005620 Cn1c2ccccc2c3cc(ccc13)C4Nc5ccccc5C(=O)N4O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P11 compound treatment 0.219 -0.0125 -1.72 0.217 -0.0146 -2.11 -2.7116 -0.9949 3118995 ChemDiv3_005621 O=S(=O)(NCC1CCCO1)c2ccc3oc4ccc(cc4c3c2)S(=O)(=O)NCC5CCCO5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P12 compound treatment 0.247 0.0155 2.15 0.25 0.0184 2.65 3.3942 0.9944 1257085 ChemDiv3_005622 Cc1cc(C)n(n1)C(=S)CSc2nc(cc(c3ccco3)c2C#N)c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P13 compound treatment 0.227 -0.00447 -0.62 0.225 -0.00662 -0.96 -1.113 -0.9775 3118996 ChemDiv3_005623 Cc1ccc(cc1CNC(=O)CSc2nc3ccccc3s2)c4nn(C)c(=O)c5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P14 compound treatment 0.221 -0.0105 -1.45 0.223 -0.00862 -1.25 -1.9034 -0.9972 1731321 ChemDiv3_005624 O=C(C(Sc1ccccc1)c2ccccc2)n3cnc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P15 compound treatment 0.218 -0.0135 -1.86 0.219 -0.0126 -1.82 -2.605 -1.0 3118997 ChemDiv3_005625 Clc1ccc(cc1)c2nn(CCC(=O)NCC3CCCO3)c(=O)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P16 compound treatment 0.226 -0.00547 -0.76 0.228 -0.00362 -0.52 -0.9043 -0.984 1308799 ChemDiv3_005626 CC1CCN(CC1)C(=O)C2c3ccccc3Oc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P17 compound treatment 0.227 -0.00447 -0.62 0.229 -0.00262 -0.38 -0.7045 -0.9727 1147363 ChemDiv3_005627 C1CCN(CC1)c2nc(N3CCCCC3)c4ccccc4n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P18 compound treatment 0.26 0.0285 3.94 0.288 0.0564 8.14 8.5454 0.9446 1443626 ChemDiv3_005628 CCOc1ccc(cc1)c2cc(C(=O)N3CCc4ccccc4C3)c5ccccc5n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P19 compound treatment 0.225 -0.00647 -0.89 0.226 -0.00562 -0.81 -1.2062 -0.9989 1859661 ChemDiv3_005629 CC(=O)Nc1ccc(NC(=O)CCSc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P20 compound treatment 0.221 -0.0105 -1.45 0.223 -0.00862 -1.25 -1.9034 -0.9972 1880335 ChemDiv3_005630 COc1ccc(cc1OC)C(=O)N2CC(C)N(CC2C)C(=O)c3ccc(OC)c(OC)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P21 compound treatment 0.222 -0.00947 -1.31 0.224 -0.00762 -1.1 -1.7036 -0.9963 3025305 ChemDiv3_005631 COc1ccc(cc1OC)C2(CCCC2)C(=O)NCCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P22 compound treatment 0.257 0.0255 3.53 0.263 0.0314 4.53 5.6989 0.9923 3119130 ChemDiv3_005632 Cc1cc(nn1Cc2ccc(o2)C(=O)Nc3ncc(Br)s3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P23 mock treatment 0.232 5.33E-4 0.07 0.231 -6.25E-4 -0.09 -0.0117 -0.1007 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2016 P24 positive control 0.234 0.00253 0.35 0.236 0.00437 0.63 0.6943 0.9612 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A01 compound treatment 0.233 0.00369 0.51 0.238 -0.00238 -0.34 0.1176 0.1915 3036308 ChemDiv3_012321 CCC(Cc1ccccc1)NS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A02 compound treatment 0.348 0.119 16.4 0.312 0.0716 10.35 18.91 0.9753 3121441 ChemDiv3_012322 O=C/1OC(=N\C1=C/c2ccco2)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A03 compound treatment 0.259 0.0297 4.1 0.286 0.0456 6.59 7.5602 0.974 3121442 ChemDiv3_012323 Cc1cc(C)cc(c1)n2c(SCC(=O)Nc3ccccc3C(F)(F)F)nc4CCSc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A04 compound treatment 0.351 0.122 16.81 0.358 0.118 16.99 23.9014 1.0 3036310 ChemDiv3_012324 O=C/1OC(=N\C1=C\NC2CCCCC2)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A05 compound treatment 0.217 -0.0123 -1.7 0.23 -0.0104 -1.5 -2.2625 -0.998 3121443 ChemDiv3_012325 O=C(Cn1cc(SCc2ccccc2)c3ccccc13)N4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A06 compound treatment 0.235 0.00569 0.79 0.245 0.00462 0.67 1.028 0.9967 3036312 ChemDiv3_012326 CC(=O)Nc1ccccc1/C(=N/C2CCCCC2)/C(=O)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A07 compound treatment 0.207 -0.0223 -3.08 0.231 -0.00937 -1.35 -3.1372 -0.9318 3121444 ChemDiv3_012327 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)NCc3ccc(F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A08 compound treatment 0.216 -0.0133 -1.84 0.229 -0.0114 -1.64 -2.4623 -0.9984 3121445 ChemDiv3_012328 CCOc1cccc2cc(C(=O)Nc3nccs3)/c(=N/c4cccc(c4)C(F)(F)F)/oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A09 compound treatment 0.295 0.0657 9.07 0.308 0.0676 9.77 13.324 0.9993 3036314 ChemDiv3_012329 CCc1ccc(NC(=O)N2CC(C)Sc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A10 compound treatment 0.22 -0.00931 -1.29 0.229 -0.0114 -1.64 -2.0715 -0.9927 3121446 ChemDiv3_012330 O=C(N1CCN(CC1)c2ccccc2)c3ccc(Cn4c(=O)[nH]c5ccccc5c4=O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A11 compound treatment 0.228 -0.00131 -0.18 0.246 0.00562 0.81 0.4463 0.5361 3036316 ChemDiv3_012331 CCc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)C3COc4ccccc4O3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A12 compound treatment 0.336 0.107 14.74 0.355 0.115 16.56 22.1297 0.9983 3121447 ChemDiv3_012332 CCC(=O)c1cc2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A13 compound treatment 0.216 -0.0133 -1.84 0.229 -0.0114 -1.64 -2.4623 -0.9984 3121448 ChemDiv3_012333 Clc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCCc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A14 compound treatment 0.215 -0.0143 -1.98 0.227 -0.0134 -1.93 -2.7643 -0.9999 1630757 ChemDiv3_012334 COc1cccc(Nc2nnc(s2)c3cc4cccc(OC)c4oc3=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A15 compound treatment 0.213 -0.0163 -2.25 0.225 -0.0154 -2.22 -3.1639 -1.0 3036368 ChemDiv3_012335 O=C(NCCc1csc2nc(nn12)c3ccccc3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A16 compound treatment 0.226 -0.00331 -0.46 0.237 -0.00338 -0.49 -0.6683 -0.9995 3036369 ChemDiv3_012336 O=C(NCc1ccc2OCOc2c1)c3sc(=S)n4c3[nH]c(=O)c5ccccc54 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A17 compound treatment 0.211 -0.0183 -2.53 0.228 -0.0124 -1.79 -3.0529 -0.9855 3036371 ChemDiv3_012337 COc1ccc(/C=N/c2ccc(cc2)C3(CC4CC5CC(C4)C3)C5)c(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A18 compound treatment 0.222 -0.00731 -1.01 0.241 6.25E-4 0.09 -0.6505 -0.6414 3036372 ChemDiv3_012338 Nc1c(nnn1c2ccc(OC(F)(F)F)cc2)C(=O)NCc3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A19 compound treatment 0.228 -0.00131 -0.18 0.247 0.00662 0.96 0.5485 0.5631 3036374 ChemDiv3_012339 Cc1cc(N/C(=N\S(=O)(=O)c2ccc(C)cc2)/c3ccccc3)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A20 compound treatment 0.241 0.0117 1.61 0.261 0.0206 2.98 3.2483 0.9586 3036375 ChemDiv3_012340 CSc1nc(cn1c2cccc(Cl)c2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A21 compound treatment 0.214 -0.0153 -2.12 0.227 -0.0134 -1.93 -2.8619 -0.999 3036377 ChemDiv3_012341 CC(C)(C)c1ccc(/C=N/n2cnnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A22 compound treatment 0.216 -0.0133 -1.84 0.231 -0.00937 -1.35 -2.258 -0.9887 3121449 ChemDiv3_012342 CCC(C)NC(=O)c1ccc(NC2=NC3CS(=O)(=O)CC3S2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A23 mock treatment 0.224 -0.00531 -0.73 0.233 -0.00737 -1.07 -1.2722 -0.9835 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 A24 positive control 0.219 -0.0103 -1.42 0.223 -0.0174 -2.51 -2.7821 -0.964 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B01 compound treatment 0.225 -0.00431 -0.6 0.234 -0.00637 -0.92 -1.0724 -0.9778 3121450 ChemDiv3_012343 CCC(Sc1nc2ccccc2c3nc4ccccc4n13)C(=O)N5CCOCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B02 compound treatment 0.26 0.0307 4.24 0.271 0.0306 4.42 6.1258 0.9998 3036379 ChemDiv3_012344 Fc1ccccc1CSC2=Nc3ccccc3C4=NC(CC(=O)NC5CCCCC5)C(=O)N42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B03 compound treatment 0.257 0.0277 3.83 0.274 0.0336 4.86 6.1391 0.993 1528378 ChemDiv3_012345 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B04 compound treatment 0.312 0.0827 11.42 0.327 0.0866 12.51 16.9253 0.999 1456817 ChemDiv3_012346 COC(=O)c1ccc2c(=O)n(c(SCC(=O)C(C)(C)C)nc2c1)c3ccc(F)c(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B05 compound treatment 0.222 -0.00731 -1.01 0.234 -0.00637 -0.92 -1.3655 -0.9989 3036381 ChemDiv3_012347 CC(CC(=O)NC1CCCCCC1)CC2=Nc3ccccc3S(=O)(=O)N2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B06 compound treatment 0.297 0.0677 9.35 0.309 0.0686 9.91 13.6215 0.9996 1665762 ChemDiv3_012348 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)NCCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B07 compound treatment 0.289 0.0597 8.25 0.299 0.0586 8.47 11.8186 0.9999 3036383 ChemDiv3_012349 Cc1cccc(NC2=Nc3ccccc3S(=O)(=O)N2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B08 compound treatment 0.238 0.00869 1.2 0.249 0.00862 1.25 1.7296 0.9998 1562044 ChemDiv3_012350 CCOC(=O)c1cc(CSc2nc3ccccc3c(=O)n2Cc4cccs4)c5OCOCc5c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B09 compound treatment 0.227 -0.00231 -0.32 0.239 -0.00138 -0.2 -0.3663 -0.9739 3121451 ChemDiv3_012351 O=C(CSc1nc2c3ccccc3sc2c(=O)n1Cc4ccccc4)NCCC5=CCCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B10 compound treatment 0.239 0.00969 1.34 0.251 0.0106 1.53 2.0316 0.9977 1694421 ChemDiv3_012352 O=C(NC1CCCCC1)C2CCC(Cn3c(=O)c4ccccc4[nH]c3=S)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B11 compound treatment 0.252 0.0227 3.13 0.259 0.0186 2.69 4.1186 0.9971 3121627 ChemDiv3_012353 O=c1n(CCCN2CCOCC2)c(SCC#N)nc3c4ccccc4sc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B12 compound treatment 0.241 0.0117 1.61 0.265 0.0246 3.56 3.6569 0.9362 1139359 ChemDiv3_012354 CC(=O)NCCn1c(SCC(=O)NCc2ccccc2)nc3ccccc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B13 compound treatment 0.253 0.0237 3.27 0.259 0.0186 2.69 4.2163 0.9953 3121628 ChemDiv3_012355 C=CCN(C(=O)CSc1nc2c3ccccc3sc2c(=O)n1Cc4cccnc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B14 compound treatment 0.234 0.00469 0.65 0.251 0.0106 1.53 1.5431 0.9264 1712288 ChemDiv3_012356 O=C(CCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B15 compound treatment 0.228 -0.00131 -0.18 0.241 6.25E-4 0.09 -0.0644 -0.3178 3036389 ChemDiv3_012357 CN(C)C(=O)C1C2NC(=S)N(c3cccc(C)c3)C1(C)Oc4c(Cl)cc(Cl)cc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B16 compound treatment 0.235 0.00569 0.79 0.272 0.0316 4.57 3.7857 0.8167 1243347 ChemDiv3_012358 O=C(CCCn1c(SCC#N)nc2ccccc2c1=O)NCc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B17 compound treatment 0.271 0.0417 5.76 0.284 0.0436 6.3 8.5281 0.999 3121629 ChemDiv3_012359 COc1ccc2C3C(C(=O)c4ccccc4)C(=O)NC5(CCCCC35)Oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B18 compound treatment 0.234 0.00469 0.65 0.249 0.00862 1.25 1.3389 0.9535 1732946 ChemDiv3_012360 CCOC(=O)N1CCN(CC1)C(=O)CCCn2c(=O)c3cc(Br)ccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B19 compound treatment 0.319 0.0897 12.39 0.33 0.0896 12.95 17.9155 0.9998 3121630 ChemDiv3_012361 CCC(SC1=Nc2ccccc2C3=NC(CC(C)C)C(=O)N31)C(=O)Nc4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B20 compound treatment 0.282 0.0527 7.28 0.317 0.0766 11.07 12.9733 0.9793 1372747 ChemDiv3_012362 CCOC(CCn1c(SCc2cccc(F)c2)nc3ccccc3c1=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B21 compound treatment 0.257 0.0277 3.83 0.269 0.0286 4.13 5.6284 0.9992 3036435 ChemDiv3_012363 CC1N=C2N(C1=O)C(=Nc3ccccc23)SCc4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B22 compound treatment 0.336 0.107 14.74 0.351 0.111 15.98 21.7211 0.9992 3036437 ChemDiv3_012364 COc1cc2[nH]c(=S)n(C3CC3)c(=O)c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B23 mock treatment 0.229 -3.12E-4 -0.04 0.245 0.00462 0.67 0.4419 0.66 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 B24 positive control 0.228 -0.00131 -0.18 0.239 -0.00138 -0.2 -0.2687 -0.999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C01 compound treatment 0.25 0.0207 2.86 0.258 0.0176 2.55 3.8211 0.9983 3036438 ChemDiv3_012365 CCN(c1ccc(OC)cc1)S(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C02 compound treatment 0.351 0.122 16.81 0.359 0.119 17.13 24.0035 1.0 3036440 ChemDiv3_012366 CC(=O)Oc1cccc(/C=C/2\N=C(OC2=O)c3ccccc3Br)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C03 compound treatment 0.29 0.0607 8.38 0.31 0.0696 10.06 13.0398 0.9959 3036441 ChemDiv3_012367 Cc1cc(C)cc(c1)n2c(SCC(=O)NCc3ccc(F)cc3)nc4CCSc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C04 compound treatment 0.262 0.0327 4.52 0.279 0.0386 5.58 7.1383 0.9945 3036443 ChemDiv3_012368 O=C/1OC(=N\C1=C/Nc2ccc3ccccc3c2)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C05 compound treatment 0.217 -0.0123 -1.7 0.23 -0.0104 -1.5 -2.2625 -0.998 3121631 ChemDiv3_012369 O=C(CSc1cn(CC(=O)N2CCOCC2)c3ccccc13)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C06 compound treatment 0.34 0.111 15.29 0.356 0.116 16.7 22.6226 0.999 3036445 ChemDiv3_012370 COc1ccc(cc1)c2nc3cc(F)c(Cl)cc3nc2c4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C07 compound treatment 0.228 -0.00131 -0.18 0.235 -0.00538 -0.78 -0.6772 -0.8494 3121632 ChemDiv3_012371 CNC(=O)CS(=O)(=O)c1cn(CC(=O)N2CCCC2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C08 compound treatment 0.227 -0.00231 -0.32 0.241 6.25E-4 0.09 -0.1621 -0.4882 3121633 ChemDiv3_012372 CCOc1cccc2cc(C(=O)Nc3nccs3)/c(=N/c4ccc(C)c(C)c4)/oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C09 compound treatment 0.25 0.0207 2.86 0.262 0.0216 3.12 4.2297 0.999 3036448 ChemDiv3_012373 CC1CN(C(=O)Nc2cccc(Cl)c2C)c3ccccc3S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C10 compound treatment 0.253 0.0237 3.27 0.256 0.0156 2.26 3.9099 0.9836 3121634 ChemDiv3_012374 CCOc1cc2[nH]c(=O)n(Cc3cccc(OC)c3)c(=O)c2cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C11 compound treatment 0.232 0.00269 0.37 0.241 6.25E-4 0.09 0.3264 0.8542 3036450 ChemDiv3_012375 CN(C)CCN(C(=O)c1ccc2ncsc2c1)c3nc4c(C)cccc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C12 compound treatment 0.275 0.0457 6.31 0.294 0.0536 7.75 9.9403 0.9948 1011589 ChemDiv3_012376 O=C(c1ccccc1)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C13 compound treatment 0.225 -0.00431 -0.6 0.234 -0.00637 -0.92 -1.0724 -0.9778 3121635 ChemDiv3_012377 Clc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCN(Cc4ccccc4)CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C14 compound treatment 0.223 -0.00631 -0.87 0.235 -0.00538 -0.78 -1.1656 -0.9983 3036453 ChemDiv3_012378 COc1ccc2oc(=O)c(cc2c1)c3nnc(NCc4ccc5OCOc5c4)s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C15 compound treatment 0.318 0.0887 12.25 0.328 0.0876 12.66 17.6136 0.9999 3121636 ChemDiv3_012379 CC1CN(CC(C)O1)c2nc(Nc3ccc(C)c(Cl)c3)c4cnn(C)c4n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C16 compound treatment 0.26 0.0307 4.24 0.291 0.0506 7.31 8.1685 0.9664 3036455 ChemDiv3_012380 CC(C)NC(=O)c1sc(=S)n2c1[nH]c(=O)c3ccc(cc32)C(=O)NC(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C17 compound treatment 0.263 0.0337 4.65 0.27 0.0296 4.28 6.3167 0.9991 3121637 ChemDiv3_012381 FC(F)(F)c1ccc(Cl)c(NC(=O)CC(=O)c2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C18 compound treatment 0.233 0.00369 0.51 0.249 0.00862 1.25 1.2412 0.9221 1593078 ChemDiv3_012382 S=c1[nH]c(cn1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C19 compound treatment 0.233 0.00369 0.51 0.238 -0.00238 -0.34 0.1176 0.1915 3121638 ChemDiv3_012383 FC(F)(F)c1cccc(/C=N/n2cnnc2SCc3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C20 compound treatment 0.274 0.0447 6.17 0.284 0.0436 6.3 8.8212 0.9999 3121639 ChemDiv3_012384 Cc1ccc(cc1)n2cc(nc2SCC(=O)NCCc3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C21 compound treatment 0.231 0.00169 0.23 0.242 0.00162 0.23 0.3308 1.0 3036458 ChemDiv3_012385 COc1ccc(/C=N/N(C)C2=NCCN2)c(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C22 compound treatment 0.221 -0.00831 -1.15 0.231 -0.00937 -1.35 -1.7696 -0.9966 3121640 ChemDiv3_012386 FC(F)(F)c1cccc(OCCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C23 mock treatment 0.229 -3.12E-4 -0.04 0.242 0.00162 0.23 0.1354 0.5675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 C24 positive control 0.231 0.00169 0.23 0.242 0.00162 0.23 0.3308 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D01 compound treatment 0.299 0.0697 9.63 0.299 0.0586 8.47 12.7955 0.998 3036460 ChemDiv3_012387 Cn1c(=O)c2nc(oc2c3ccccc13)c4ccccc4I 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D02 compound treatment 0.248 0.0187 2.58 0.252 0.0116 1.68 3.0129 0.9783 3036503 ChemDiv3_012388 O=C(CC1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccccc4)NCCc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D03 compound treatment 0.222 -0.00731 -1.01 0.229 -0.0114 -1.64 -1.8762 -0.9727 3036504 ChemDiv3_012389 O=C(CCCC1=Nc2ccccc2S(=O)(=O)N1)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D04 compound treatment 0.267 0.0377 5.21 0.261 0.0206 2.98 5.7882 0.9649 1076056 ChemDiv3_012390 CCCCn1c(=O)c2ccccc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D05 compound treatment 0.281 0.0517 7.14 0.291 0.0506 7.31 10.22 0.9999 3036506 ChemDiv3_012391 Cc1cccc(N2CCN(CC2)C(=O)CC3(CC4=Nc5ccccc5S(=O)(=O)N4)CCCC3)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D06 compound treatment 0.224 -0.00531 -0.73 0.233 -0.00737 -1.07 -1.2722 -0.9835 1698753 ChemDiv3_012392 Clc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D07 compound treatment 0.311 0.0817 11.29 0.321 0.0806 11.65 16.2148 0.9999 3036508 ChemDiv3_012393 COC(=O)c1ccccc1n2c(N)c(C#N)c(N)c(C#N)c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D08 compound treatment 0.269 0.0397 5.48 0.288 0.0476 6.88 8.7413 0.9937 1613927 ChemDiv3_012394 Clc1ccc(CSc2nc3ccccc3c(=O)n2Cc4cccs4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D09 compound treatment 0.249 0.0197 2.72 0.267 0.0266 3.85 4.6427 0.9856 3121641 ChemDiv3_012395 COc1ccc(CCn2c(=O)c3sc4ccccc4c3[nH]c2=S)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D10 compound treatment 0.248 0.0187 2.58 0.256 0.0156 2.26 3.4215 0.9978 1185287 ChemDiv3_012396 COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)Nc4ccccc4Cl)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D11 compound treatment 0.262 0.0327 4.52 0.264 0.0236 3.41 5.6062 0.9905 3036510 ChemDiv3_012397 COc1ccc(CCNC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCO)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D12 compound treatment 0.301 0.0717 9.9 0.329 0.0886 12.8 16.055 0.992 1434889 ChemDiv3_012398 COc1ccc(NC(=O)CCCn2c(=O)c3ccccc3[nH]c2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D13 compound treatment 0.28 0.0507 7.0 0.299 0.0586 8.47 10.9394 0.9955 3036513 ChemDiv3_012399 Cc1ccccc1Nc2sc(C(=O)c3ccccc3)c(N)c2C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D14 compound treatment 0.241 0.0117 1.61 0.246 0.00562 0.81 1.7163 0.9495 1547109 ChemDiv3_012400 O=C(CC#N)Nn1c(=O)c2ccccc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D15 compound treatment 0.216 -0.0133 -1.84 0.226 -0.0144 -2.08 -2.7687 -0.9982 3121642 ChemDiv3_012401 COc1cccc2C3NC(=S)NC(C)(Oc12)C3C(=O)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D16 compound treatment 0.24 0.0107 1.48 0.241 6.25E-4 0.09 1.1079 0.7489 1155487 ChemDiv3_012402 Fc1cccc(CSc2nc3ccccc3c(=O)n2CCC(=O)NCCc4ccccc4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D17 compound treatment 0.275 0.0457 6.31 0.295 0.0546 7.89 10.0424 0.9939 3121643 ChemDiv3_012403 COc1ccccc1C(=O)C2C3CC(C)(NC2=O)Oc4ccc(Cl)cc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D18 compound treatment 0.231 0.00169 0.23 0.242 0.00162 0.23 0.3308 1.0 1421160 ChemDiv3_012404 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCCC(=O)N4CCCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D19 compound treatment 0.242 0.0127 1.75 0.249 0.00862 1.25 2.1204 0.986 3036517 ChemDiv3_012405 CCC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCc4cc(=O)n5ccccc5n4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D20 compound treatment 0.22 -0.00931 -1.29 0.231 -0.00937 -1.35 -1.8673 -0.9997 3121644 ChemDiv3_012406 Clc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D21 compound treatment 0.227 -0.00231 -0.32 0.233 -0.00737 -1.07 -0.9792 -0.8804 3121645 ChemDiv3_012407 O=C(CCC1N=C2N(C1=O)C(=S)Nc3ccccc23)N4CCN(CC4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D22 compound treatment 0.219 -0.0103 -1.42 0.23 -0.0104 -1.5 -2.0671 -0.9997 3036519 ChemDiv3_012408 CC1CCN(CC1)C(=O)CSc2nc3cc4OCOc4cc3c(=O)n2CCC5=CCCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D23 mock treatment 0.231 0.00169 0.23 0.237 -0.00338 -0.49 -0.1799 -0.3329 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 D24 positive control 0.232 0.00269 0.37 0.239 -0.00138 -0.2 0.1221 0.29 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E01 compound treatment 0.224 -0.00531 -0.73 0.223 -0.0174 -2.51 -2.2936 -0.8772 3121646 ChemDiv3_012409 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(C)CC(=O)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E02 compound treatment 0.217 -0.0123 -1.7 0.226 -0.0144 -2.08 -2.671 -0.9951 1660760 ChemDiv3_012410 CCOc1ncccc1C(=O)Nc2cccc(c2)C(=O)Nc3cccc(c3)S(=O)(=O)CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E03 compound treatment 0.252 0.0227 3.13 0.262 0.0216 3.12 4.425 1.0 3121828 ChemDiv3_012411 COc1cccc(c1)n2c(SCC(=O)NC3CCCC3)nc4CCSc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E04 compound treatment 0.273 0.0437 6.04 0.291 0.0506 7.31 9.4385 0.9955 3121829 ChemDiv3_012412 Cc1ccc(cc1)C2=N/C(=C/Nc3ccccc3)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E05 compound treatment 0.221 -0.00831 -1.15 0.23 -0.0104 -1.5 -1.8717 -0.9914 3036522 ChemDiv3_012413 NC(=O)CSc1cn(CC(=O)N2CCOCC2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E06 compound treatment 0.4 0.171 23.58 0.416 0.176 25.37 34.6121 0.9993 3121830 ChemDiv3_012414 O=C(NCCc1ccccc1)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E07 compound treatment 0.216 -0.0133 -1.84 0.231 -0.00937 -1.35 -2.258 -0.9887 3036524 ChemDiv3_012415 CN(C(=O)CS(=O)(=O)c1cn(CC(=O)N2CCOCC2)c3ccccc13)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E08 compound treatment 0.258 0.0287 3.96 0.276 0.0356 5.15 6.4411 0.9917 3121831 ChemDiv3_012416 COc1ccc2o/c(=N\c3ccc(cc3)C(=O)O)/c(cc2c1)C(=O)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E09 compound treatment 0.219 -0.0103 -1.42 0.236 -0.00438 -0.63 -1.4543 -0.9331 3036578 ChemDiv3_012417 FC(F)(F)c1cccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E10 compound treatment 0.27 0.0407 5.62 0.284 0.0436 6.3 8.4305 0.9984 3036580 ChemDiv3_012418 COc1ccc(NC(=O)CCn2c(=O)[nH]c3ccccc3c2=O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E11 compound treatment 0.317 0.0877 12.11 0.313 0.0726 10.49 15.9838 0.9974 3036582 ChemDiv3_012419 CN(C)CCN(C(=O)c1ccco1)c2nc3cc4OCOc4cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E12 compound treatment 0.234 0.00469 0.65 0.249 0.00862 1.25 1.3389 0.9535 3036583 ChemDiv3_012420 CCCC(=O)c1cc2cc(Cl)ccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E13 compound treatment 0.233 0.00369 0.51 0.243 0.00262 0.38 0.6283 0.9894 3036585 ChemDiv3_012421 COc1ccc(NC(=O)c2cncc(NS(=O)(=O)c3ccc(C)cc3)c2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E14 compound treatment 0.327 0.0977 13.5 0.319 0.0786 11.36 17.5735 0.9963 1332200 ChemDiv3_012422 CC1CCC(CC1)NC(=O)CCC(=O)Nc2nc(cs2)c3cc4ccccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E15 compound treatment 0.223 -0.00631 -0.87 0.232 -0.00837 -1.21 -1.4721 -0.9871 3121832 ChemDiv3_012423 COc1ccc(Nc2nc(NCCN3CCOCC3)nc4n(C)ncc24)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E16 compound treatment 0.225 -0.00431 -0.6 0.237 -0.00338 -0.49 -0.766 -0.995 3036587 ChemDiv3_012424 Cc1ccc(cc1)S(=O)(=O)c2nnn3c2[nH]c(=O)c4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E17 compound treatment 0.246 0.0167 2.31 0.268 0.0276 3.99 4.4517 0.966 1438027 ChemDiv3_012425 Cc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E18 compound treatment 0.257 0.0277 3.83 0.259 0.0186 2.69 4.6071 0.9852 3036589 ChemDiv3_012426 CC(C)(C)c1cn(c2ccc(F)cc2)c(=S)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E19 compound treatment 0.223 -0.00631 -0.87 0.227 -0.0134 -1.93 -1.9828 -0.9354 3121833 ChemDiv3_012427 Brc1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E20 compound treatment 0.245 0.0157 2.17 0.255 0.0146 2.11 3.0262 0.9999 3121834 ChemDiv3_012428 COc1ccc(OC)c(c1)n2cc(nc2SC)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E21 compound treatment 0.222 -0.00731 -1.01 0.229 -0.0114 -1.64 -1.8762 -0.9727 3036591 ChemDiv3_012429 CN(/N=C/c1ccncc1)C2=NCCN2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E22 compound treatment 0.238 0.00869 1.2 0.242 0.00162 0.23 1.0146 0.8297 3121835 ChemDiv3_012430 Fc1cccc(CSc2nc3ccccc3c4nc5ccccc5n24)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E23 mock treatment 0.228 -0.00131 -0.18 0.237 -0.00338 -0.49 -0.4729 -0.9093 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 E24 positive control 0.231 0.00169 0.23 0.24 -3.75E-4 -0.05 0.1265 0.5287 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F01 compound treatment 0.228 -0.00131 -0.18 0.237 -0.00338 -0.49 -0.4729 -0.9093 3121836 ChemDiv3_012431 COc1ccccc1NC(=O)c2sc3nc([nH]c(=O)c3c2C)c4cc5cccc(OC)c5oc4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F02 compound treatment 0.244 0.0147 2.03 0.257 0.0166 2.4 3.1328 0.9965 3036593 ChemDiv3_012432 Cc1cc(C)n(CCc2nc3c4ccccc4[nH]c(=S)n3n2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F03 compound treatment 0.22 -0.00931 -1.29 0.23 -0.0104 -1.5 -1.9694 -0.9971 3036595 ChemDiv3_012433 O=C(CCC1=Nc2ccccc2S(=O)(=O)N1)NC3CCCCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F04 compound treatment 0.227 -0.00231 -0.32 0.236 -0.00438 -0.63 -0.6728 -0.9501 1258951 ChemDiv3_012434 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCc4ccc(Cl)cc4)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F05 compound treatment 0.232 0.00269 0.37 0.248 0.00762 1.1 1.0413 0.8959 3121837 ChemDiv3_012435 Cc1cc(C)cc(NC(=O)CN2C=NS(=O)(=O)c3ccccc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F06 compound treatment 0.311 0.0817 11.29 0.304 0.0636 9.19 14.4784 0.9948 1505938 ChemDiv3_012436 Fc1cccc(F)c1CSc2nc3ccccc3c(=O)n2Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F07 compound treatment 0.307 0.0777 10.73 0.321 0.0806 11.65 15.824 0.9992 3121838 ChemDiv3_012437 CCOc1ccccc1n2c(N)c(C#N)c(N)c(C#N)c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F08 compound treatment 0.231 0.00169 0.23 0.255 0.0146 2.11 1.6586 0.7804 1429743 ChemDiv3_012438 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F09 compound treatment 0.246 0.0167 2.31 0.268 0.0276 3.99 4.4517 0.966 3121839 ChemDiv3_012439 NS(=O)(=O)c1ccc(CCn2c(=O)c3sc4ccccc4c3[nH]c2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F10 compound treatment 0.266 0.0367 5.07 0.287 0.0466 6.73 8.3461 0.9902 1534154 ChemDiv3_012440 O=c1n(C2CCCC2)c(=S)[nH]c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F11 compound treatment 0.224 -0.00531 -0.73 0.236 -0.00438 -0.63 -0.9658 -0.9972 3121840 ChemDiv3_012441 CCCCn1c(SCC(=O)NCc2ccccc2)nc3c4ccccc4sc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F12 compound treatment 0.221 -0.00831 -1.15 0.231 -0.00937 -1.35 -1.7696 -0.9966 1166876 ChemDiv3_012442 O=C(CSc1nc2ccccc2c(=O)n1NC(=O)c3ccccc3)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F13 compound treatment 0.294 0.0647 8.94 0.307 0.0666 9.62 13.1241 0.9993 3036601 ChemDiv3_012443 O/C(=C\1/C(=O)Nc2ccccc12)/C(=O)NCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F14 compound treatment 0.229 -3.12E-4 -0.04 0.236 -0.00438 -0.63 -0.4774 -0.7537 1501852 ChemDiv3_012444 O=C(CCn1c(SCC#N)nc2ccccc2c1=O)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F15 compound treatment 0.278 0.0487 6.73 0.295 0.0546 7.89 10.3355 0.9968 3036644 ChemDiv3_012445 CCN1C(=S)NC2C(C(=O)Nc3ccc(Cl)cc3)C1(C)Oc4ccc(Br)cc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F16 compound treatment 0.257 0.0277 3.83 0.269 0.0286 4.13 5.6284 0.9992 1342889 ChemDiv3_012446 Fc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CCCC(=O)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F17 compound treatment 0.233 0.00369 0.51 0.243 0.00262 0.38 0.6283 0.9894 1680152 ChemDiv3_012447 COc1ccc2oc(=O)c(cc2c1)c3nc(cs3)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F18 compound treatment 0.253 0.0237 3.27 0.259 0.0186 2.69 4.2163 0.9953 1164499 ChemDiv3_012448 CCOC(=O)CSc1nc2ccc(Br)cc2c3nc4ccccc4n13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F19 compound treatment 0.299 0.0697 9.63 0.314 0.0736 10.63 14.3275 0.9988 3036647 ChemDiv3_012449 CC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccc(Br)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F20 compound treatment 0.257 0.0277 3.83 0.277 0.0366 5.29 6.4455 0.9873 3036648 ChemDiv3_012450 Fc1cccc(CSc2nc3ccccc3c(=O)n2C4CC4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F21 compound treatment 0.259 0.0297 4.1 0.264 0.0236 3.41 5.3131 0.9958 3121841 ChemDiv3_012451 O=C(CCC1N=C2N(C1=O)C(=S)Nc3ccccc23)NC4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F22 compound treatment 0.23 6.88E-4 0.09 0.231 -0.00937 -1.35 -0.8904 -0.6559 3121842 ChemDiv3_012452 Fc1ccccc1N2CCN(CC2)C(=O)CCCn3c(=O)c4cc5OCOc5cc4[nH]c3=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F23 mock treatment 0.227 -0.00231 -0.32 0.238 -0.00238 -0.34 -0.4685 -0.9994 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 F24 positive control 0.231 0.00169 0.23 0.24 -3.75E-4 -0.05 0.1265 0.5287 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G01 compound treatment 0.227 -0.00231 -0.32 0.235 -0.00538 -0.78 -0.7749 -0.923 3036650 ChemDiv3_012453 CC1Cc2cc(ccc2N1C(=O)C)S(=O)(=O)N(C)CC(=O)N(C)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G02 compound treatment 0.254 0.0247 3.41 0.297 0.0566 8.18 8.1952 0.9248 1923050 ChemDiv3_012454 O=C/1OC(=N\C1=C/c2ccccc2)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G03 compound treatment 0.219 -0.0103 -1.42 0.231 -0.00937 -1.35 -1.965 -0.9997 3121843 ChemDiv3_012455 CCN(CC)C(=O)Cn1cc(SCC(=O)N2CCCCC2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G04 compound treatment 0.273 0.0437 6.04 0.28 0.0396 5.72 8.315 0.9996 3036653 ChemDiv3_012456 Cc1ccc(cc1C)N2C(SCC2=O)c3ccccc3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G05 compound treatment 0.216 -0.0133 -1.84 0.228 -0.0124 -1.79 -2.5644 -0.9999 3121844 ChemDiv3_012457 O=C(CSc1cn(CC(=O)N2CCOCC2)c3ccccc13)NCc4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G06 compound treatment 0.273 0.0437 6.04 0.293 0.0526 7.6 9.6428 0.9935 3121845 ChemDiv3_012458 O=C(NCc1ccccc1)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G07 compound treatment 0.287 0.0577 7.97 0.303 0.0626 9.05 12.0318 0.998 3036656 ChemDiv3_012459 CCOC(=O)C1=C(CN2CCC(=CC2)c3ccccc3)NC(=O)NC1c4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G08 compound treatment 0.32 0.0907 12.53 0.336 0.0956 13.81 18.626 0.9988 3121846 ChemDiv3_012460 COc1ccc(NC(=O)c/2cc3ccc(O)cc3o\c2=N/c4ccc(cc4)C(=O)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G09 compound treatment 0.24 0.0107 1.48 0.251 0.0106 1.53 2.1293 0.9998 3036658 ChemDiv3_012461 CN(C)CCN(C(=O)c1ccco1)c2nc3ccc(C)cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G10 compound treatment 0.222 -0.00731 -1.01 0.232 -0.00837 -1.21 -1.5697 -0.996 3121847 ChemDiv3_012462 CCOc1cc2[nH]c(=O)n(CCC(=O)NC3CCCCC3C)c(=O)c2cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G11 compound treatment 0.22 -0.00931 -1.29 0.227 -0.0134 -1.93 -2.2758 -0.9805 3036660 ChemDiv3_012463 COc1ccc2sc(nc2c1)N(CCN(C)C)C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G12 compound treatment 0.241 0.0117 1.61 0.245 0.00462 0.67 1.6141 0.9237 3121848 ChemDiv3_012464 CCc1ccc(/N=c/2\oc3c(C)ncc(CO)c3cc2C(=O)N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G13 compound treatment 0.229 -3.12E-4 -0.04 0.236 -0.00438 -0.63 -0.4774 -0.7537 3121849 ChemDiv3_012465 Cc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)NC3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G14 compound treatment 0.344 0.115 15.84 0.354 0.114 16.41 22.809 0.9998 1158935 ChemDiv3_012466 CCc1ccc(Nc2nc(cs2)c3cc4ccccc4oc3=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G15 compound treatment 0.226 -0.00331 -0.46 0.236 -0.00438 -0.63 -0.7704 -0.9874 3121850 ChemDiv3_012467 COc1ccc(Nc2nc(nc3n(C)ncc23)N4CCN(CCO)CC4)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G16 compound treatment 0.226 -0.00331 -0.46 0.234 -0.00637 -0.92 -0.9747 -0.9479 3036662 ChemDiv3_012468 Clc1ccc(cc1)c2nnn3c2[nH]c(=O)c4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G17 compound treatment 0.222 -0.00731 -1.01 0.233 -0.00737 -1.07 -1.4676 -0.9996 1396293 ChemDiv3_012469 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G18 compound treatment 0.278 0.0487 6.73 0.311 0.0706 10.2 11.9697 0.9796 3036664 ChemDiv3_012470 Cc1ccc(c(C)c1)n2cc([nH]c2=S)c3ccc4OCOc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G19 compound treatment 0.227 -0.00231 -0.32 0.242 0.00162 0.23 -0.0599 -0.1512 3122038 ChemDiv3_012471 CCOC(=O)c1c(C)c(C)sc1NC(=O)Nc2ccc(Cl)c(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G20 compound treatment 0.289 0.0597 8.25 0.285 0.0446 6.45 10.3887 0.9926 3122039 ChemDiv3_012472 Cc1ccc(NC(=O)CSc2nc(cn2c3cccc(Cl)c3)c4ccc5OCOc5c4)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G21 compound treatment 0.221 -0.00831 -1.15 0.231 -0.00937 -1.35 -1.7696 -0.9966 3036666 ChemDiv3_012473 C(=N/n1cnnc1)\c2ccccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G22 compound treatment 0.257 0.0277 3.83 0.255 0.0146 2.11 4.1985 0.9608 3035632 ChemDiv3_012474 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)NCc5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G23 mock treatment 0.228 -0.00131 -0.18 0.237 -0.00338 -0.49 -0.4729 -0.9093 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 G24 positive control 0.229 -3.12E-4 -0.04 0.239 -0.00138 -0.2 -0.171 -0.8412 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H01 compound treatment 0.274 0.0447 6.17 0.281 0.0406 5.87 8.5148 0.9997 3035560 ChemDiv3_012475 COc1ccc(OCC(=O)Nn2c(=O)c3cccnc3[nH]c2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H02 compound treatment 0.227 -0.00231 -0.32 0.232 -0.00837 -1.21 -1.0813 -0.8642 3035562 ChemDiv3_012476 Cc1cc(C)n(CCc2nc3c4ccccc4nc(SCc5ccc(C)cc5)n3n2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H03 compound treatment 0.219 -0.0103 -1.42 0.23 -0.0104 -1.5 -2.0671 -0.9997 3035563 ChemDiv3_012477 O=C(CCCC1=Nc2ccccc2S(=O)(=O)N1)N3CCCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H04 compound treatment 0.227 -0.00231 -0.32 0.237 -0.00338 -0.49 -0.5706 -0.979 1726645 ChemDiv3_012478 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCC(=O)C(C)(C)C)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H05 compound treatment 0.306 0.0767 10.59 0.306 0.0656 9.48 14.1943 0.9985 3035566 ChemDiv3_012479 Clc1ccc(cc1)N2C(=O)N(Cc3cc(=O)n4ccccc4n3)c5ccccc5S2(=O)=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H06 compound treatment 0.224 -0.00531 -0.73 0.237 -0.00338 -0.49 -0.8637 -0.9802 1217521 ChemDiv3_012480 Cc1ccc(CSc2nc3ccccc3c(=O)n2CCc4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H07 compound treatment 0.315 0.0857 11.84 0.318 0.0776 11.21 16.2991 0.9996 3035568 ChemDiv3_012481 Nc1c(C#N)c(N)n(CC2CCCO2)c(=S)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H08 compound treatment 0.226 -0.00331 -0.46 0.237 -0.00338 -0.49 -0.6683 -0.9995 1739931 ChemDiv3_012482 COC(=O)c1ccc2c3nc4ccccc4n3c(SCc5ccccc5Cl)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H09 compound treatment 0.344 0.115 15.84 0.382 0.142 20.46 25.6689 0.992 3122040 ChemDiv3_012483 CCCCC(CC)Cn1c(=O)c2sc3ccccc3c2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H10 compound treatment 0.247 0.0177 2.44 0.26 0.0196 2.83 3.7323 0.9973 1290113 ChemDiv3_012484 O=c1n(CC2COc3ccccc3O2)c(=S)[nH]c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H11 compound treatment 0.223 -0.00631 -0.87 0.227 -0.0134 -1.93 -1.9828 -0.9354 3122041 ChemDiv3_012485 CCCCn1c(SCC(=O)NC2CCCC2)nc3c4ccccc4sc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H12 compound treatment 0.259 0.0297 4.1 0.278 0.0376 5.43 6.7431 0.9904 1516861 ChemDiv3_012486 O=C(Cc1ccccc1)Nn2c(SCC(=O)c3ccccc3)nc4ccccc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H13 compound treatment 0.276 0.0467 6.45 0.296 0.0556 8.03 10.2422 0.9941 3122042 ChemDiv3_012487 O/C(=C\1/C(=O)Nc2ccccc12)/C(=O)Nc3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H14 compound treatment 0.264 0.0347 4.79 0.292 0.0516 7.46 8.6614 0.9771 1425823 ChemDiv3_012488 COc1cccc(NC(=O)CCn2c(=O)c3ccccc3[nH]c2=S)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H15 compound treatment 0.246 0.0167 2.31 0.257 0.0166 2.4 3.3282 0.9998 3035573 ChemDiv3_012489 CC1(CC2NC(=S)N1c3ccccc3)Oc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H16 compound treatment 0.24 0.0107 1.48 0.247 0.00662 0.96 1.7207 0.978 1579697 ChemDiv3_012490 CCOC(CCn1c(SCc2cc(=O)n3ccccc3n2)nc4ccccc4c1=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H17 compound treatment 0.246 0.0167 2.31 0.258 0.0176 2.55 3.4304 0.9988 1412676 ChemDiv3_012491 CC(=O)Oc1ccc2cc(c3nc(c(C)s3)c4ccccc4)c(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H18 compound treatment 0.227 -0.00231 -0.32 0.234 -0.00637 -0.92 -0.877 -0.8998 3122043 ChemDiv3_012492 CCC(C)NC(=O)CSc1nc2ccc(Br)cc2c3nc4ccccc4n13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H19 compound treatment 0.269 0.0397 5.48 0.283 0.0426 6.16 8.2306 0.9983 3122044 ChemDiv3_012493 CC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCc4ccccc4F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H20 compound treatment 0.29 0.0607 8.38 0.305 0.0646 9.33 12.5291 0.9986 3035576 ChemDiv3_012494 CCN(CCCn1c(=O)c2cc3OCOc3cc2[nH]c1=S)c4cccc(C)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H21 compound treatment 0.268 0.0387 5.34 0.28 0.0396 5.72 7.8265 0.9994 3122045 ChemDiv3_012495 O=C(CC1N=C2N(C1=O)C(=S)Nc3ccccc23)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H22 compound treatment 0.268 0.0387 5.34 0.265 0.0246 3.56 6.2944 0.9804 3035579 ChemDiv3_012496 C=CCNC(=O)CCn1c(=O)c2cc3OCOc3cc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H23 mock treatment 0.233 0.00369 0.51 0.242 0.00162 0.23 0.5262 0.9381 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 H24 positive control 0.23 6.88E-4 0.09 0.244 0.00362 0.52 0.4374 0.822 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I01 compound treatment 0.337 0.108 14.88 0.348 0.108 15.55 21.5124 0.9998 3122046 ChemDiv3_012497 Cc1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2Cc4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I02 compound treatment 0.288 0.0587 8.11 0.289 0.0486 7.02 10.6995 0.9974 3035581 ChemDiv3_012498 COc1ccc(cc1)C2=N/C(=C\c3ccco3)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I03 compound treatment 0.221 -0.00831 -1.15 0.231 -0.00937 -1.35 -1.7696 -0.9966 3122047 ChemDiv3_012499 CCN(CC)C(=O)Cn1cc(SCC(=O)N)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I04 compound treatment 0.216 -0.0133 -1.84 0.23 -0.0104 -1.5 -2.3602 -0.9948 1325020 ChemDiv3_012500 COc1ccc(cc1)N2C(SCC2=O)c3cccc(OC)c3OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I05 compound treatment 0.229 -3.12E-4 -0.04 0.235 -0.00538 -0.78 -0.5795 -0.7453 3035634 ChemDiv3_012501 CC1CCN(CC1)C(=O)Cn2cc(SCC(=O)N3CCc4ccccc34)c5ccccc25 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I06 compound treatment 0.34 0.111 15.29 0.355 0.115 16.56 22.5204 0.9992 3035635 ChemDiv3_012502 CCC(C)NC(=O)c1ccc2nc(c3cccs3)c(nc2c1)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I07 compound treatment 0.227 -0.00231 -0.32 0.235 -0.00538 -0.78 -0.7749 -0.923 3035637 ChemDiv3_012503 Cc1cc([nH]n1)C(=O)N2CCN(Cc3ccccc3)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I08 compound treatment 0.223 -0.00631 -0.87 0.236 -0.00438 -0.63 -1.0635 -0.9875 3035638 ChemDiv3_012504 COc1ccc(CNC(=O)CCn2c(=O)[nH]c3ccccc3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I09 compound treatment 0.237 0.00769 1.06 0.255 0.0146 2.11 2.2447 0.9494 3122048 ChemDiv3_012505 COc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I10 compound treatment 0.224 -0.00531 -0.73 0.235 -0.00538 -0.78 -1.068 -0.9996 3122049 ChemDiv3_012506 CC1CCCC(NC(=O)C2CCC(Cn3c(=O)[nH]c4ccccc4c3=O)CC2)C1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I11 compound treatment 0.229 -3.12E-4 -0.04 0.236 -0.00438 -0.63 -0.4774 -0.7537 3035641 ChemDiv3_012507 COc1ccc2sc(nc2c1)N(CCN(C)C)C(=O)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I12 compound treatment 0.227 -0.00231 -0.32 0.242 0.00162 0.23 -0.0599 -0.1512 3122050 ChemDiv3_012508 Cc1ncc(CO)c2cc(C(=O)Nc3ccccc3)/c(=N/c4ccccc4)/oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I13 compound treatment 0.287 0.0577 7.97 0.299 0.0586 8.47 11.6232 0.9995 3035643 ChemDiv3_012509 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)Nc3ccc(cc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I14 compound treatment 0.225 -0.00431 -0.6 0.237 -0.00338 -0.49 -0.766 -0.995 3122051 ChemDiv3_012510 CC(=O)N(c1nc(cs1)c2cc3ccccc3oc2=O)c4cccc(C)c4C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I15 compound treatment 0.234 0.00469 0.65 0.243 0.00262 0.38 0.726 0.9675 3035645 ChemDiv3_012511 COc1ccccc1N2CCN(CC2)c3nc(Nc4ccc(C)cc4)c5cnn(C)c5n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I16 compound treatment 0.246 0.0167 2.31 0.258 0.0176 2.55 3.4304 0.9988 3122052 ChemDiv3_012512 FC(F)(F)c1cccc(c1)c2nnn3c2[nH]c(=O)c4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I17 compound treatment 0.295 0.0657 9.07 0.29 0.0496 7.17 11.4855 0.9932 3035648 ChemDiv3_012513 Oc1c(Br)cc(Br)cc1/C=N/N2C(=O)CSC2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I18 compound treatment 0.24 0.0107 1.48 0.255 0.0146 2.11 2.5378 0.9847 3122053 ChemDiv3_012514 Fc1ccc(cc1)n2cc([nH]c2=S)c3ccc4OCOc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I19 compound treatment 0.25 0.0207 2.86 0.256 0.0156 2.26 3.6168 0.9932 3122054 ChemDiv3_012515 C1COCCOc2cc(/N=C\c3c[nH]c4ccccc34)ccc2OCCO1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I20 compound treatment 0.226 -0.00331 -0.46 0.242 0.00162 0.23 -0.1576 -0.3065 3035650 ChemDiv3_012516 CC(C)(C)C1=Nn2c(nnc2SC1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I21 compound treatment 0.236 0.00669 0.92 0.255 0.0146 2.11 2.1471 0.9312 3122055 ChemDiv3_012517 CN(/N=C/c1ccc(C)o1)C2=NCCN2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I22 compound treatment 0.222 -0.00731 -1.01 0.235 -0.00538 -0.78 -1.2633 -0.9915 3035652 ChemDiv3_012518 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)NCCc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I23 mock treatment 0.23 6.88E-4 0.09 0.245 0.00462 0.67 0.5396 0.7996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 I24 positive control 0.228 -0.00131 -0.18 0.244 0.00362 0.52 0.242 0.4368 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J01 compound treatment 0.261 0.0317 4.38 0.266 0.0256 3.7 5.7128 0.9965 3122056 ChemDiv3_012519 C=CCNC(=O)Cn1c(=O)c2cccnc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J02 compound treatment 0.223 -0.00631 -0.87 0.244 0.00362 0.52 -0.2464 -0.2422 3122057 ChemDiv3_012520 Cc1nc2c3ccccc3nc(SCc4cc(F)cc5COCOc45)n2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J03 compound treatment 0.217 -0.0123 -1.7 0.239 -0.00138 -0.2 -1.3432 -0.7843 3035654 ChemDiv3_012521 CC(CC(=O)O)CC1=Nc2ccccc2S(=O)(=O)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J04 compound treatment 0.262 0.0327 4.52 0.275 0.0346 5.0 6.7297 0.9987 1191560 ChemDiv3_012522 CC1CCCC(C1C)n2c(=O)c3ccccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J05 compound treatment 0.249 0.0197 2.72 0.277 0.0366 5.29 5.664 0.9522 3122058 ChemDiv3_012523 Clc1ccc(cc1)N2C(=O)N(CC(=O)N3CCCc4ccccc34)c5ccccc5S2(=O)=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J06 compound treatment 0.303 0.0737 10.18 0.332 0.0916 13.23 16.5568 0.9916 1311026 ChemDiv3_012524 Cc1ccc(CSc2nc3ccccc3c(=O)n2Cc4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J07 compound treatment 0.257 0.0277 3.83 0.279 0.0386 5.58 6.6498 0.983 3035657 ChemDiv3_012525 CSc1nc2c3ccccc3sc2c(=O)n1c4ccc(C)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J08 compound treatment 0.236 0.00669 0.92 0.254 0.0136 1.97 2.0449 0.9406 1488534 ChemDiv3_012526 CC1CCCCC1NC(=O)c2ccc3c(=O)n(CCCN4CCCC4=O)c(=S)[nH]c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J09 compound treatment 0.287 0.0577 7.97 0.302 0.0616 8.9 11.9296 0.9985 3122059 ChemDiv3_012527 Fc1ccccc1N2CCN(CCCn3c(=O)c4sc5ccccc5c4[nH]c3=S)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J10 compound treatment 0.228 -0.00131 -0.18 0.24 -3.75E-4 -0.05 -0.1665 -0.8799 1733498 ChemDiv3_012528 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J11 compound treatment 0.275 0.0457 6.31 0.31 0.0696 10.06 11.5745 0.9748 3035717 ChemDiv3_012529 O=c1n(C2CCCCC2)c(SCC#N)nc3c4ccccc4sc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J12 compound treatment 0.228 -0.00131 -0.18 0.241 6.25E-4 0.09 -0.0644 -0.3178 3035719 ChemDiv3_012530 O=c1n(CCn2c(SCC#N)nc3ccccc3c2=O)c(SCC#N)nc4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J13 compound treatment 0.224 -0.00531 -0.73 0.233 -0.00737 -1.07 -1.2722 -0.9835 3443559 ChemDiv3_012531 CCOC(=O)C1C2NC(=S)N(c3ccccc3)C1(C)Oc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J14 compound treatment 0.246 0.0167 2.31 0.267 0.0266 3.85 4.3496 0.97 1675251 ChemDiv3_012532 O=C(NCC1CCCO1)c2ccc(Cn3c(=O)c4ccccc4[nH]c3=S)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J15 compound treatment 0.26 0.0307 4.24 0.277 0.0366 5.29 6.7386 0.994 3035721 ChemDiv3_012533 COc1ccc(CCN2C(=S)NC3CC2(C)Oc4c(OC)cc(Br)cc34)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J16 compound treatment 0.251 0.0217 3.0 0.265 0.0246 3.56 4.6338 0.9964 1729416 ChemDiv3_012534 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)Nc3ccc(C)cc3)nc4ccccc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J17 compound treatment 0.261 0.0317 4.38 0.267 0.0266 3.85 5.8149 0.9979 1733506 ChemDiv3_012535 CC(=O)Oc1ccc2cc(c3nc-4c(CCc5ccccc45)s3)c(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J18 compound treatment 0.226 -0.00331 -0.46 0.234 -0.00637 -0.92 -0.9747 -0.9479 1577061 ChemDiv3_012536 CCC(Sc1nc2ccc(Br)cc2c3nc4ccccc4n13)C(=O)NCC5CCCO5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J19 compound treatment 0.281 0.0517 7.14 0.29 0.0496 7.17 10.1178 1.0 3122243 ChemDiv3_012537 COc1ccc(CCNC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J20 compound treatment 0.242 0.0127 1.75 0.244 0.00362 0.52 1.6097 0.8799 3035725 ChemDiv3_012538 Clc1ccccc1CCn2c(=O)c3cc4OCOc4cc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J21 compound treatment 0.275 0.0457 6.31 0.283 0.0426 6.16 8.8168 0.9999 3122244 ChemDiv3_012539 CC(C)NC(=O)CC1N=C2N(C1=O)C(=S)Nc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J22 compound treatment 0.294 0.0647 8.94 0.244 0.00362 0.52 6.6894 0.7473 3122245 ChemDiv3_012540 CCOC(=O)N1CCN(CC1)C(=O)CCn2c(=O)c3cc4OCOc4cc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J23 mock treatment 0.231 0.00169 0.23 0.244 0.00362 0.52 0.5351 0.9336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 J24 positive control 0.233 0.00369 0.51 0.245 0.00462 0.67 0.8326 0.991 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K01 compound treatment 0.27 0.0407 5.62 0.277 0.0366 5.29 7.7155 0.9995 3035727 ChemDiv3_012541 O=C(CSc1nc2CCSc2c(=O)n1Cc3ccccc3)NC4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K02 compound treatment 0.321 0.0917 12.67 0.332 0.0916 13.23 18.3152 0.9998 3122246 ChemDiv3_012542 COc1ccc(/C=C/2\N=C(\OC2=O)/C=C/c3ccc(C)cc3)cc1OC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K03 compound treatment 0.228 -0.00131 -0.18 0.245 0.00462 0.67 0.3442 0.4972 3035729 ChemDiv3_012543 CCN(CC)C(=O)Cn1cc(SCc2ccccc2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K04 compound treatment 0.234 0.00469 0.65 0.254 0.0136 1.97 1.8495 0.8927 1694239 ChemDiv3_012544 Cc1onc(c1C(=O)NCC2(CC3CC4CC(C3)C2)C4)c5ccccc5Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K05 compound treatment 0.216 -0.0133 -1.84 0.236 -0.00438 -0.63 -1.7473 -0.8985 3122247 ChemDiv3_012545 CNC(=O)CSc1cn(CC(=O)N2CCC(C)CC2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K06 compound treatment 0.269 0.0397 5.48 0.286 0.0456 6.59 8.537 0.9958 3035731 ChemDiv3_012546 CC(C)CCNC(=O)c1ccc2nc(c3cccs3)c(nc2c1)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K07 compound treatment 0.239 0.00969 1.34 0.243 0.00262 0.38 1.2145 0.8731 3122248 ChemDiv3_012547 Fc1ccc(cc1)c2cc([nH]n2)C(=O)N3CCN(CC3)c4cccc(Cl)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K08 compound treatment 0.23 6.88E-4 0.09 0.242 0.00162 0.23 0.2331 0.9207 3035733 ChemDiv3_012548 O=C(CCn1c(=O)[nH]c2ccccc2c1=O)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K09 compound treatment 0.253 0.0237 3.27 0.267 0.0266 3.85 5.0334 0.9968 3122249 ChemDiv3_012549 CN(C)CCN(C(=O)c1ccc(Br)cc1)c2nc3ccc(Cl)cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K10 compound treatment 0.232 0.00269 0.37 0.245 0.00462 0.67 0.7349 0.9616 3122250 ChemDiv3_012550 CC(C)CCNC(=O)C1CCC(Cn2c(=O)[nH]c3ccccc3c2=O)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K11 compound treatment 0.222 -0.00731 -1.01 0.233 -0.00737 -1.07 -1.4676 -0.9996 3035735 ChemDiv3_012551 CN(C)CCN(C(=O)C)c1nc2cc(C)cc(C)c2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K12 compound treatment 0.224 -0.00531 -0.73 0.235 -0.00538 -0.78 -1.068 -0.9996 3122251 ChemDiv3_012552 Cc1ncc(CO)c2cc(c3nnc(Nc4cc(ccc4Cl)C(F)(F)F)s3)c(=O)oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K13 compound treatment 0.228 -0.00131 -0.18 0.234 -0.00637 -0.92 -0.7793 -0.8304 3035787 ChemDiv3_012553 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)NCc3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K14 compound treatment 0.226 -0.00331 -0.46 0.236 -0.00438 -0.63 -0.7704 -0.9874 3035789 ChemDiv3_012554 CCOC(=O)c1ccc(cc1)N(C(=O)C)c2nc(cs2)c3cc4cccc(OCC)c4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K15 compound treatment 0.22 -0.00931 -1.29 0.232 -0.00837 -1.21 -1.7651 -0.9995 3035791 ChemDiv3_012555 COc1ccc(cc1OC)C(CC(=O)NCc2ccc(C)cc2)N3Cc4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K16 compound treatment 0.23 6.88E-4 0.09 0.237 -0.00338 -0.49 -0.2776 -0.5588 3035793 ChemDiv3_012556 COc1ccc(CCNC(=O)c2nnn(c2N)c3cccc(C)c3)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K17 compound treatment 0.372 0.143 19.71 0.379 0.139 20.02 28.0977 1.0 3035794 ChemDiv3_012557 COc1cccc(/C=N/N2C(=O)CSC2=S)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K18 compound treatment 0.231 0.00169 0.23 0.257 0.0166 2.4 1.8629 0.7721 3035796 ChemDiv3_012558 COc1cccc2cc(c3cn(c4ccc(F)c(F)c4)c(=S)[nH]3)c(=O)oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K19 compound treatment 0.228 -0.00131 -0.18 0.242 0.00162 0.23 0.0378 0.1273 3122252 ChemDiv3_012559 Clc1ccc(/C=N\c2ccc3OCCOCCOCCOc3c2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K20 compound treatment 0.234 0.00469 0.65 0.246 0.00562 0.81 1.0324 0.9937 3035798 ChemDiv3_012560 Brc1ccc(cc1)C2=Nn3c(SC2)nc4ccccc4c3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K21 compound treatment 0.244 0.0147 2.03 0.268 0.0276 3.99 4.2564 0.9508 3122253 ChemDiv3_012561 Cc1ccc(cc1)C2=N/C(=C\c3ccco3)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K22 compound treatment 0.225 -0.00431 -0.6 0.237 -0.00338 -0.49 -0.766 -0.995 3035800 ChemDiv3_012562 CCN(C(=O)CSc1nc2ccccc2c3nc4ccccc4n13)c5cccc(C)c5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K23 mock treatment 0.231 0.00169 0.23 0.243 0.00262 0.38 0.433 0.9727 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 K24 positive control 0.233 0.00369 0.51 0.243 0.00262 0.38 0.6283 0.9894 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L01 compound treatment 0.261 0.0317 4.38 0.261 0.0206 2.98 5.2021 0.9824 3122254 ChemDiv3_012563 COC(=O)c1cccnc1NC(=S)NC(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L02 compound treatment 0.222 -0.00731 -1.01 0.229 -0.0114 -1.64 -1.8762 -0.9727 3122255 ChemDiv3_012564 CCC(Sc1nc2ccccc2c3nc(C)nn13)C(=O)Nc4cc(OC)ccc4OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L03 compound treatment 0.224 -0.00531 -0.73 0.23 -0.0104 -1.5 -1.5787 -0.946 3035802 ChemDiv3_012565 OC(=O)CC1(CC2=Nc3ccccc3S(=O)(=O)N2)CCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L04 compound treatment 0.242 0.0127 1.75 0.257 0.0166 2.4 2.9375 0.988 1540848 ChemDiv3_012566 CSc1nc2ccccc2c(=O)n1C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L05 compound treatment 0.242 0.0127 1.75 0.269 0.0286 4.13 4.1631 0.927 3122256 ChemDiv3_012567 Cc1ccc(cc1Cl)N2C(=O)N(CC(=O)Nc3ccccc3)c4ccccc4S2(=O)=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L06 compound treatment 0.256 0.0267 3.69 0.27 0.0296 4.28 5.6329 0.9972 1685213 ChemDiv3_012568 Brc1ccccc1OCC(=O)Nn2c(=O)c3ccccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L07 compound treatment 0.222 -0.00731 -1.01 0.24 -3.75E-4 -0.05 -0.7526 -0.744 3122257 ChemDiv3_012569 O=C(CSc1nc2c3ccccc3sc2c(=O)n1c4ccccc4)N5CCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L08 compound treatment 0.24 0.0107 1.48 0.254 0.0136 1.97 2.4357 0.99 3035806 ChemDiv3_012570 O=C(NCCCN1CCOCC1)c2ccc3c(=O)n(CCCN4CCCC4=O)c(=S)[nH]c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L09 compound treatment 0.274 0.0447 6.17 0.308 0.0676 9.77 11.2725 0.9755 3122258 ChemDiv3_012571 CCN(CC)CCn1c(SCC(=O)Nc2cccc(OC)c2)nc3c4ccccc4sc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L10 compound treatment 0.279 0.0497 6.86 0.287 0.0466 6.73 9.6161 1.0 1627035 ChemDiv3_012572 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L11 compound treatment 0.222 -0.00731 -1.01 0.235 -0.00538 -0.78 -1.2633 -0.9915 3035808 ChemDiv3_012573 Cc1ccc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CC5CCCO5)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L12 compound treatment 0.232 0.00269 0.37 0.248 0.00762 1.1 1.0413 0.8959 1362140 ChemDiv3_012574 CCOC(Cn1c(SCC#N)nc2ccccc2c1=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L13 compound treatment 0.224 -0.00531 -0.73 0.234 -0.00637 -0.92 -1.1701 -0.9937 3122259 ChemDiv3_012575 CCOc1cccc2C3NC(=S)N(CCOC)C(C)(Oc12)C3C(=O)Nc4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L14 compound treatment 0.243 0.0137 1.89 0.245 0.00462 0.67 1.8095 0.9023 1500074 ChemDiv3_012576 O=C(NC1CCCCC1)c2ccc(Cn3c(=O)c4ccccc4[nH]c3=S)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L15 compound treatment 0.265 0.0357 4.93 0.284 0.0436 6.3 7.942 0.9926 3122260 ChemDiv3_012577 CC1(CC2C(C(=O)c3ccccc3)C(=O)N1)Oc4c(Br)cc(Br)cc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L16 compound treatment 0.233 0.00369 0.51 0.254 0.0136 1.97 1.7519 0.8617 1425362 ChemDiv3_012578 COc1ccc(CCNC(=O)CCn2c(SCC#N)nc3ccccc3c2=O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L17 compound treatment 0.263 0.0337 4.65 0.27 0.0296 4.28 6.3167 0.9991 3036527 ChemDiv3_012579 CCN(CC)C(=O)CSC1=Nc2ccccc2C3=NC(Cc4c[nH]c5ccccc45)C(=O)N31 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L18 compound treatment 0.232 0.00269 0.37 0.242 0.00162 0.23 0.4285 0.9755 1179823 ChemDiv3_012580 CN(Cc1ccccc1)C(=O)CSc2nc3ccc(Br)cc3c4nc5ccccc5n24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L19 compound treatment 0.278 0.0487 6.73 0.292 0.0516 7.46 10.0291 0.9987 3036529 ChemDiv3_012581 CCc1ccc(NC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L20 compound treatment 0.284 0.0547 7.56 0.297 0.0566 8.18 11.1259 0.9992 3036532 ChemDiv3_012582 OC(=O)CCCn1c(=O)c2cc3OCOc3cc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L21 compound treatment 0.273 0.0437 6.04 0.278 0.0376 5.43 8.1107 0.9986 3036534 ChemDiv3_012583 O=C(CCC1N=C2N(C1=O)C(=Nc3ccccc23)SCC#N)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L22 compound treatment 0.227 -0.00231 -0.32 0.241 6.25E-4 0.09 -0.1621 -0.4882 3036535 ChemDiv3_012584 O=C(CCn1c(=O)c2cc3OCOc3cc2[nH]c1=S)NC4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L23 mock treatment 0.231 0.00169 0.23 0.241 6.25E-4 0.09 0.2287 0.9147 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 L24 positive control 0.231 0.00169 0.23 0.24 -3.75E-4 -0.05 0.1265 0.5287 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M01 compound treatment 0.329 0.0997 13.77 0.333 0.0926 13.38 19.1988 0.9999 3122261 ChemDiv3_012585 Cc1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2CCc4ccccc4)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M02 compound treatment 0.301 0.0717 9.9 0.284 0.0436 6.3 11.4588 0.9762 3036538 ChemDiv3_012586 Clc1ccc(cc1)C2=N/C(=C\c3ccccc3)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M03 compound treatment 0.221 -0.00831 -1.15 0.227 -0.0134 -1.93 -2.1781 -0.9691 3122262 ChemDiv3_012587 CCN(CC)C(=O)Cn1cc(SCC(=O)N(C(C)C)C(C)C)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M04 compound treatment 0.251 0.0217 3.0 0.261 0.0206 2.98 4.2252 1.0 3036541 ChemDiv3_012588 Nc1ccc(Br)cc1c2nc3ccccc3[nH]c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M05 compound treatment 0.225 -0.00431 -0.6 0.236 -0.00438 -0.63 -0.8681 -0.9996 3122263 ChemDiv3_012589 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M06 compound treatment 0.301 0.0717 9.9 0.314 0.0736 10.63 14.5229 0.9994 3036544 ChemDiv3_012590 O=C(NCc1cccnc1)c2ccc3nc(c4ccco4)c(nc3c2)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M07 compound treatment 0.245 0.0157 2.17 0.256 0.0156 2.26 3.1284 0.9998 3122457 ChemDiv3_012591 Clc1ccc(cc1)c2cc([nH]n2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M08 compound treatment 0.238 0.00869 1.2 0.249 0.00862 1.25 1.7296 0.9998 3036547 ChemDiv3_012592 O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NCCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M09 compound treatment 0.233 0.00369 0.51 0.246 0.00562 0.81 0.9348 0.9747 3036603 ChemDiv3_012593 CN(C)CCN(C(=O)C1CCCCC1)c2nc3ccc(Br)cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M10 compound treatment 0.243 0.0137 1.89 0.259 0.0186 2.69 3.2394 0.9851 3036605 ChemDiv3_012594 CC1CCCCC1NC(=O)c2ccc3c(=O)n(Cc4ccc5OCOc5c4)c(=O)[nH]c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M11 compound treatment 0.246 0.0167 2.31 0.257 0.0166 2.4 3.3282 0.9998 3036607 ChemDiv3_012595 CN(C)CCN(C(=O)CN1C(=O)c2ccccc2C1=O)c3nc4c(F)cc(F)cc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M12 compound treatment 0.229 -3.12E-4 -0.04 0.238 -0.00238 -0.34 -0.2731 -0.7899 3036609 ChemDiv3_012596 Cc1ncc(CO)c2cc(C(=O)Nc3ccc(I)cc3)c(=O)oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M13 compound treatment 0.224 -0.00531 -0.73 0.228 -0.0124 -1.79 -1.7829 -0.9227 3036611 ChemDiv3_012597 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCN(CC3)c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M14 compound treatment 0.243 0.0137 1.89 0.252 0.0116 1.68 2.5245 0.9982 3036613 ChemDiv3_012598 CC(=O)N(c1nc(cs1)c2cc3ccccc3oc2=O)c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M15 compound treatment 0.218 -0.0113 -1.56 0.232 -0.00837 -1.21 -1.9605 -0.992 3122458 ChemDiv3_012599 CCOC(=O)c1sc2ncn(/N=C/c3ccc4OCCOc4c3)c(=O)c2c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M16 compound treatment 0.268 0.0387 5.34 0.279 0.0386 5.58 7.7244 0.9998 3036615 ChemDiv3_012600 Cc1cccc(NC(=O)c2nnn(c2N)c3cccc(c3)C(F)(F)F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M17 compound treatment 0.258 0.0287 3.96 0.26 0.0196 2.83 4.8069 0.9865 3122459 ChemDiv3_012601 Cc1c(/N=C/c2cc(Br)cc(Br)c2O)cccc1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M18 compound treatment 0.235 0.00569 0.79 0.243 0.00262 0.38 0.8237 0.9441 3036617 ChemDiv3_012602 Cc1cccc(c1)n2cc([nH]c2=S)c3cc4cc(Cl)ccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M19 compound treatment 0.231 0.00169 0.23 0.24 -3.75E-4 -0.05 0.1265 0.5287 3122460 ChemDiv3_012603 OC(=O)c1cc(/C=N\c2ccc3OCCOCCOCCOc3c2)ccc1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M20 compound treatment 0.222 -0.00731 -1.01 0.229 -0.0114 -1.64 -1.8762 -0.9727 3122461 ChemDiv3_012604 O=C(NCCc1ccccc1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M21 compound treatment 0.272 0.0427 5.9 0.283 0.0426 6.16 8.5237 0.9998 3036619 ChemDiv3_012605 Fc1ccccc1C2=N/C(=C\c3cccc(c3)C(F)(F)F)/C(=O)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M22 compound treatment 0.231 0.00169 0.23 0.238 -0.00238 -0.34 -0.0777 -0.1874 3122462 ChemDiv3_012606 CC1CC(C)CN(C1)C(=O)CSc2nc3ccccc3c4nc5ccccc5n24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M23 mock treatment 0.23 6.88E-4 0.09 0.243 0.00262 0.38 0.3353 0.8577 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 M24 positive control 0.23 6.88E-4 0.09 0.235 -0.00538 -0.78 -0.4818 -0.616 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N01 compound treatment 0.238 0.00869 1.2 0.243 0.00262 0.38 1.1168 0.8873 3036622 ChemDiv3_012607 Cc1ccc(C)c(Cn2c(C)nc3n(c4ccccc4)c(=S)sc3c2=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N02 compound treatment 0.262 0.0327 4.52 0.262 0.0216 3.12 5.4019 0.9838 3122463 ChemDiv3_012608 Cc1nc2c3ccccc3nc(SCc4cccc(c4)C(F)(F)F)n2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N03 compound treatment 0.221 -0.00831 -1.15 0.23 -0.0104 -1.5 -1.8717 -0.9914 3122464 ChemDiv3_012609 CC(CC(=O)N1CCc2ccccc2C1)CC3=Nc4ccccc4S(=O)(=O)N3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N04 compound treatment 0.288 0.0587 8.11 0.296 0.0556 8.03 11.4145 1.0 1247070 ChemDiv3_012610 Fc1ccccc1CSc2nc3ccccc3c(=O)n2CCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N05 compound treatment 0.247 0.0177 2.44 0.252 0.0116 1.68 2.9152 0.9832 3122465 ChemDiv3_012611 CCN(C(=O)CN1C(=O)N(c2ccc(C)c(Cl)c2)S(=O)(=O)c3ccccc13)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N06 compound treatment 0.317 0.0877 12.11 0.318 0.0776 11.21 16.4945 0.9993 3036627 ChemDiv3_012612 Clc1ccc(CNC(=O)c2ccc3c4nc5ccccc5n4c(=S)[nH]c3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N07 compound treatment 0.262 0.0327 4.52 0.267 0.0266 3.85 5.9126 0.9968 3035583 ChemDiv3_012613 NC(=O)CSc1nc2c3ccccc3sc2c(=O)n1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N08 compound treatment 0.289 0.0597 8.25 0.282 0.0416 6.01 10.0822 0.988 1730072 ChemDiv3_012614 CC(C)NC(=O)c1ccc2c(=O)n(Cc3ccco3)c(=S)[nH]c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N09 compound treatment 0.229 -3.12E-4 -0.04 0.265 0.0246 3.56 2.4846 0.6985 3035585 ChemDiv3_012615 Cc1cc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCc5ccccc5)n[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N10 compound treatment 0.225 -0.00431 -0.6 0.233 -0.00737 -1.07 -1.1745 -0.9623 1416226 ChemDiv3_012616 Clc1ccc(CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N11 compound treatment 0.262 0.0327 4.52 0.266 0.0256 3.7 5.8105 0.9951 3035588 ChemDiv3_012617 O=C(CSc1nc2c3ccccc3sc2c(=O)n1CC4CCCO4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N12 compound treatment 0.277 0.0477 6.59 0.306 0.0656 9.48 11.3613 0.9842 1410674 ChemDiv3_012618 CCOC(Cn1c(SCc2c(F)cccc2Cl)nc3ccccc3c1=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N13 compound treatment 0.267 0.0377 5.21 0.274 0.0336 4.86 7.116 0.9994 3122466 ChemDiv3_012619 COc1cccc2C3NC(=S)N(c4ccc(F)cc4)C(C)(Oc12)C3C(=O)Nc5ccc(C)cc5C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N14 compound treatment 0.22 -0.00931 -1.29 0.228 -0.0124 -1.79 -2.1737 -0.987 1265476 ChemDiv3_012620 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)NC(C)CC)nc3ccccc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N15 compound treatment 0.259 0.0297 4.1 0.263 0.0226 3.27 5.211 0.9937 3035592 ChemDiv3_012621 COc1ccc(/C=C/C(=C/2\C3C4CCCC4(Oc5ccccc35)N(C)C2=O)/O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N16 compound treatment 0.285 0.0557 7.69 0.307 0.0666 9.62 12.245 0.9938 1632146 ChemDiv3_012622 Brc1ccc2[nH]c(=S)n(Cc3ccc(cc3)C(=O)NCc4ccco4)c(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N17 compound treatment 0.266 0.0367 5.07 0.299 0.0586 8.47 9.5718 0.9699 3122467 ChemDiv3_012623 Fc1ccc(cc1)C(=O)CSC2=Nc3ccccc3C4=NC(Cc5ccccc5)C(=O)N42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N18 compound treatment 0.268 0.0387 5.34 0.267 0.0266 3.85 6.4987 0.987 1249888 ChemDiv3_012624 CCOC(CCn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)OC)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N19 compound treatment 0.275 0.0457 6.31 0.284 0.0436 6.3 8.9189 1.0 3122468 ChemDiv3_012625 COc1cccc(NC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N20 compound treatment 0.234 0.00469 0.65 0.24 -3.75E-4 -0.05 0.4196 0.6457 3035596 ChemDiv3_012626 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4)C(=O)Nc5ccccc5OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N21 compound treatment 0.257 0.0277 3.83 0.269 0.0286 4.13 5.6284 0.9992 3122469 ChemDiv3_012627 O=C(CCC1N=C2N(C1=O)C(=Nc3ccccc23)SCC#N)NC4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N22 compound treatment 0.222 -0.00731 -1.01 0.23 -0.0104 -1.5 -1.774 -0.9816 3122470 ChemDiv3_012628 Cc1cccc(N2CCN(CC2)C(=O)CCn3c(=O)c4cc5OCOc5cc4[nH]c3=S)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N23 mock treatment 0.229 -3.12E-4 -0.04 0.241 6.25E-4 0.09 0.0333 0.3329 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 N24 positive control 0.23 6.88E-4 0.09 0.237 -0.00338 -0.49 -0.2776 -0.5588 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O01 compound treatment 0.261 0.0317 4.38 0.276 0.0356 5.15 6.7342 0.9968 3035598 ChemDiv3_012629 O=C(CSc1nc2CCSc2c(=O)n1CCc3ccccc3)Nc4nccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O02 compound treatment 0.283 0.0537 7.42 0.289 0.0486 7.02 10.2111 0.9996 3122471 ChemDiv3_012630 O=C/1O/C(=N\C1=C\c2ccco2)/C=C/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O03 compound treatment 0.219 -0.0103 -1.42 0.227 -0.0134 -1.93 -2.3735 -0.9888 3122472 ChemDiv3_012631 O=C(CSc1cn(CC(=O)N2CCCC2)c3ccccc13)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O04 compound treatment 0.392 0.163 22.48 0.408 0.168 24.21 33.0135 0.9993 1274089 ChemDiv3_012632 Oc1ncnc2nc(c3ccccc3)c(nc12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O05 compound treatment 0.222 -0.00731 -1.01 0.229 -0.0114 -1.64 -1.8762 -0.9727 3122473 ChemDiv3_012633 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)Nc3ccccc3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O06 compound treatment 0.224 -0.00531 -0.73 0.237 -0.00338 -0.49 -0.8637 -0.9802 3035659 ChemDiv3_012634 Clc1ccc(/N=c/2\oc3ccccc3cc2C(=O)Nc4nccs4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O07 compound treatment 0.22 -0.00931 -1.29 0.233 -0.00737 -1.07 -1.663 -0.9956 3035660 ChemDiv3_012635 O=C(NCc1ccccc1)N2CCSc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O08 compound treatment 0.237 0.00769 1.06 0.25 0.00962 1.39 1.7341 0.9912 3035662 ChemDiv3_012636 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(Cn3c(=O)[nH]c4ccccc4c3=O)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O09 compound treatment 0.224 -0.00531 -0.73 0.237 -0.00338 -0.49 -0.8637 -0.9802 3035664 ChemDiv3_012637 CCc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)c3ccc(cc3)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O10 compound treatment 0.233 0.00369 0.51 0.243 0.00262 0.38 0.6283 0.9894 3035665 ChemDiv3_012638 O=C(NCc1ccccc1)c2ccc3c(=O)n(CCC4=CCCCC4)c(=O)[nH]c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O11 compound treatment 0.229 -3.12E-4 -0.04 0.238 -0.00238 -0.34 -0.2731 -0.7899 3035668 ChemDiv3_012639 O=C(Nc1ccc2OCOc2c1)c3cncc(NS(=O)(=O)c4ccccc4)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O12 compound treatment 0.212 -0.0173 -2.39 0.231 -0.00937 -1.35 -2.6488 -0.9637 3122474 ChemDiv3_012640 Cc1ncc(CO)c2cc(C(=O)NC3=CC4OCOC4C=C3)/c(=N/c5ccccc5)/oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O13 compound treatment 0.224 -0.00531 -0.73 0.224 -0.0164 -2.37 -2.1915 -0.8849 3035669 ChemDiv3_012641 COc1cccc(C(=O)NCCc2csc3nc(nn23)c4ccc(C)cc4)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O14 compound treatment 0.224 -0.00531 -0.73 0.229 -0.0114 -1.64 -1.6808 -0.934 3122475 ChemDiv3_012642 Brc1ccc2oc(=O)c(cc2c1)c3csc(NC(=O)CCC(=O)N4CCCC4)n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O15 compound treatment 0.278 0.0487 6.73 0.295 0.0546 7.89 10.3355 0.9968 3035672 ChemDiv3_012643 Cc1cc(c(C)s1)c2cn(/N=C/c3ccc(Cl)cc3Cl)c(N)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O16 compound treatment 0.249 0.0197 2.72 0.256 0.0156 2.26 3.5191 0.9957 3122476 ChemDiv3_012644 Nc1c(nnn1c2cccc(c2)C(F)(F)F)C(=O)NCCC3=CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O17 compound treatment 0.307 0.0777 10.73 0.316 0.0756 10.92 15.3133 1.0 3035674 ChemDiv3_012645 COc1cccc(/C=N/c2cccc(C(=O)O)c2C)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O18 compound treatment 0.276 0.0467 6.45 0.277 0.0366 5.29 8.3016 0.9952 1347140 ChemDiv3_012646 COc1ccc(cc1)n2cc(nc2SCC(=O)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O19 compound treatment 0.221 -0.00831 -1.15 0.229 -0.0114 -1.64 -1.9739 -0.9847 3035676 ChemDiv3_012647 CN(/N=C/c1ccc(cc1)C(C)(C)C)C2=NCCN2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O20 compound treatment 0.221 -0.00831 -1.15 0.232 -0.00837 -1.21 -1.6674 -0.9997 3122477 ChemDiv3_012648 O=C(N1CCCCC1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O21 compound treatment 0.279 0.0497 6.86 0.296 0.0556 8.03 10.5353 0.9969 3035679 ChemDiv3_012649 CC(=O)Oc1cccc(/C=C/2\N=C(OC2=O)c3ccco3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O22 compound treatment 0.245 0.0157 2.17 0.252 0.0116 1.68 2.7198 0.992 3122478 ChemDiv3_012650 CCN(Cc1ccccc1)C(=O)CSc2nc3ccccc3c4nc5ccccc5n24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O23 mock treatment 0.228 -0.00131 -0.18 0.241 6.25E-4 0.09 -0.0644 -0.3178 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 O24 positive control 0.224 -0.00531 -0.73 0.235 -0.00538 -0.78 -1.068 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P01 compound treatment 0.24 0.0107 1.48 0.237 -0.00338 -0.49 0.6993 0.4498 3035682 ChemDiv3_012651 Cc1ccc2oc(=O)c(cc2c1)c3nc4ccccc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P02 compound treatment 0.257 0.0277 3.83 0.275 0.0346 5.0 6.2413 0.9912 3122479 ChemDiv3_012652 Cc1n[nH]c(C)c1CCc2nc3c4ccccc4nc(SCc5ccc(C)cc5)n3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P03 compound treatment 0.226 -0.00331 -0.46 0.227 -0.0134 -1.93 -1.6897 -0.8511 3122670 ChemDiv3_012653 CC(CC(=O)NCc1ccccc1)CC2=Nc3ccccc3S(=O)(=O)N2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P04 compound treatment 0.23 6.88E-4 0.09 0.241 6.25E-4 0.09 0.131 0.9997 1381410 ChemDiv3_012654 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)NCc4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P05 compound treatment 0.23 6.88E-4 0.09 0.234 -0.00637 -0.92 -0.584 -0.6308 3035739 ChemDiv3_012655 O=S1(=O)NC(CC#N)Nc2ccccc21 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P06 compound treatment 0.229 -3.12E-4 -0.04 0.241 6.25E-4 0.09 0.0333 0.3329 1142918 ChemDiv3_012656 CCOC(=O)CSc1nc2ccccc2c(=O)n1CCN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P07 compound treatment 0.236 0.00669 0.92 0.247 0.00662 0.96 1.33 0.9998 3035742 ChemDiv3_012657 CCOC(=O)CSc1nc2c3ccccc3sc2c(=O)n1Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P08 compound treatment 0.253 0.0237 3.27 0.271 0.0306 4.42 5.442 0.989 1618070 ChemDiv3_012658 O=C(NCc1ccccc1)C2CCC(Cn3c(=O)c4ccccc4[nH]c3=S)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P09 compound treatment 0.236 0.00669 0.92 0.248 0.00762 1.1 1.4321 0.9962 3035744 ChemDiv3_012659 CCC(Sc1nc2c3ccccc3sc2c(=O)n1CCc4ccccc4)C(=O)N5CCOCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P10 compound treatment 0.215 -0.0143 -1.98 0.228 -0.0124 -1.79 -2.6621 -0.9987 1164910 ChemDiv3_012660 CC(=O)NCCn1c(SCc2ccccc2C)nc3ccccc3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P11 compound treatment 0.222 -0.00731 -1.01 0.234 -0.00637 -0.92 -1.3655 -0.9989 3035746 ChemDiv3_012661 CCOC(CCn1c(SC)nc2c3ccccc3sc2c1=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P12 compound treatment 0.223 -0.00631 -0.87 0.224 -0.0164 -2.37 -2.2892 -0.9081 1398709 ChemDiv3_012662 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCCN4CCC(C)CC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P13 compound treatment 0.297 0.0677 9.35 0.299 0.0586 8.47 12.6001 0.9988 3122671 ChemDiv3_012663 Cc1ccc(cc1)N2C(=S)NC3C(C(=O)Nc4ccc(C)cc4C)C2(C)Oc5ccc(Cl)cc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P14 compound treatment 0.248 0.0187 2.58 0.25 0.00962 1.39 2.8086 0.9578 3035748 ChemDiv3_012664 FC(F)(F)c1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4CCCO4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P15 compound treatment 0.264 0.0347 4.79 0.278 0.0376 5.43 7.2315 0.998 3122672 ChemDiv3_012665 CN1C(=O)C(C2CC1(C)Oc3ccc(Br)cc23)c4nnc(Nc5ccc(C)cc5)s4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P16 compound treatment 0.258 0.0287 3.96 0.264 0.0236 3.41 5.2154 0.9972 1567339 ChemDiv3_012666 CC(C)NC(=O)CCCn1c(=O)c2cc(Br)ccc2[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P17 compound treatment 0.249 0.0197 2.72 0.264 0.0236 3.41 4.3362 0.9937 3122673 ChemDiv3_012667 Cc1ccc(CNC(=O)CSC2=Nc3ccccc3C4=NC(Cc5ccccc5)C(=O)N42)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P18 compound treatment 0.225 -0.00431 -0.6 0.23 -0.0104 -1.5 -1.481 -0.9183 1672792 ChemDiv3_012668 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)c3ccccc3)nc4ccccc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P19 compound treatment 0.333 0.104 14.32 0.338 0.0976 14.1 20.1002 1.0 3122674 ChemDiv3_012669 CC1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccc(O)c(O)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P20 compound treatment 0.227 -0.00231 -0.32 0.231 -0.00937 -1.35 -1.1834 -0.8506 3122675 ChemDiv3_012670 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4)C(=O)NCc5ccc(C)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P21 compound treatment 0.271 0.0417 5.76 0.275 0.0346 5.0 7.6089 0.9975 3035754 ChemDiv3_012671 O=C(CSC1=Nc2ccccc2C3=NC(CC(=O)NCc4ccco4)C(=O)N31)NCc5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P22 compound treatment 0.298 0.0687 9.49 0.314 0.0736 10.63 14.2299 0.9984 3122676 ChemDiv3_012672 O=C(NCCC1=CCCCC1)c2ccc(Cn3c(=O)c4cc5OCOc5cc4[nH]c3=S)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P23 mock treatment 0.23 6.88E-4 0.09 0.237 -0.00338 -0.49 -0.2776 -0.5588 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2036 P24 positive control 0.225 -0.00431 -0.6 0.24 -3.75E-4 -0.05 -0.4596 -0.7682 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A01 compound treatment 0.214 -0.0122 -1.68 0.215 -0.0109 -1.58 -2.3077 -0.9995 3063827 Maybridge4_001761 Cc1noc(C)c1S(=O)(=O)NCC2COc3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A02 compound treatment 0.285 0.0588 8.13 0.279 0.0531 7.66 11.165 0.9996 3179242 Maybridge4_001762 COc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A03 compound treatment 0.245 0.0188 2.6 0.243 0.0171 2.46 3.5805 0.9996 3063828 Maybridge4_001763 COc1ccc(cc1)c2nnsc2N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A04 compound treatment 0.211 -0.0152 -2.1 0.211 -0.0149 -2.16 -3.0093 -0.9999 3179243 Maybridge4_001764 CCn1c(Cn2nnc3ccccc23)nnc1SCC(=O)c4ccc(Br)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A05 compound treatment 0.337 0.111 15.31 0.336 0.11 15.9 22.0666 0.9998 3179244 Maybridge4_001765 C1Cc2cc(ccc2O1)C3Nc4ccccc4-c5cccn35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A06 compound treatment 0.226 -1.88E-4 -0.03 0.231 0.00506 0.73 0.4988 0.6816 3063829 Maybridge4_001766 S=C(Nc1ccccc1)N2c3ccccc3Sc4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A07 compound treatment 0.218 -0.00819 -1.13 0.218 -0.00794 -1.15 -1.6105 -1.0 3179245 Maybridge4_001767 O=S(=O)(NCc1ccco1)c2ccc(Oc3c(C#N)cccc3C#N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A08 compound treatment 0.216 -0.0102 -1.41 0.216 -0.00994 -1.44 -2.0102 -1.0 3063830 Maybridge4_001768 Nc1nc(Sc2nnc(c3ccncc3)n2c4ccccc4)ncc1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A09 compound treatment 0.246 0.0198 2.74 0.247 0.0211 3.04 4.0867 0.9986 3179246 Maybridge4_001769 Clc1ccc(COC(=O)c2ccc3ccccc3n2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A10 compound treatment 0.225 -0.00119 -0.16 0.226 6.25E-5 0.01 -0.1096 -0.6672 3063831 Maybridge4_001770 O=C(CSc1nnc(o1)c2ccncc2)NC(=O)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A11 compound treatment 0.227 8.12E-4 0.11 0.228 0.00206 0.3 0.29 0.911 1526124 Maybridge4_001771 S=c1[nH]nc(c2ccncc2)n1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A12 compound treatment 0.235 0.00881 1.22 0.233 0.00706 1.02 1.5822 0.9961 3179247 Maybridge4_001772 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A13 compound treatment 0.214 -0.0122 -1.68 0.215 -0.0109 -1.58 -2.3077 -0.9995 3063832 Maybridge4_001773 Cc1cc(C)c2c(n1)sc3c(=O)n(/N=C/c4ccccc4)cnc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A14 compound treatment 0.223 -0.00319 -0.44 0.235 0.00906 1.31 0.6142 0.4447 3179248 Maybridge4_001774 Fc1ccc(Cn2nc3sc4ccccc4n3c(=O)c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A15 compound treatment 0.318 0.0918 12.68 0.317 0.0911 13.15 18.2699 0.9998 3063833 Maybridge4_001775 Clc1ccccc1Cn2nnc3c(=S)[nH]cnc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A16 compound treatment 0.246 0.0198 2.74 0.24 0.0141 2.03 3.3718 0.9892 3179249 Maybridge4_001776 CCOC(=O)c1c(C)c(C)sc1NC(=S)Nc2cc(C)nn2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A17 compound treatment 0.231 0.00481 0.66 0.233 0.00706 1.02 1.1915 0.9785 3063834 Maybridge4_001777 CCOC(=O)c1nnn2c1nc(N(CC)CC)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A18 compound treatment 0.215 -0.0112 -1.55 0.217 -0.00894 -1.29 -2.0057 -0.996 3179250 Maybridge4_001778 Cc1cc(C)c2c(n1)sc3c(=O)n(NC(=O)Nc4ccccc4)c(C)nc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A19 compound treatment 0.228 0.00181 0.25 0.23 0.00406 0.59 0.592 0.9279 3063835 Maybridge4_001779 CCOC(=O)c1nn(c2ccccc2)c3nc(=O)c(C#N)c(c4ccccc4)n13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A20 compound treatment 0.244 0.0178 2.46 0.237 0.0111 1.6 2.87 0.9781 3179251 Maybridge4_001780 O=C(Cn1c(=O)n(c2ccccc2)c(=O)c3cc(sc13)c4ccccc4)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A21 compound treatment 0.212 -0.0142 -1.96 0.214 -0.0119 -1.72 -2.6052 -0.998 3179252 Maybridge4_001781 COc1ccc(cc1)n2ncc(NC(=O)NCc3ccccn3)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A22 compound treatment 0.217 -0.00919 -1.27 0.217 -0.00894 -1.29 -1.8104 -1.0 3063836 Maybridge4_001782 COc1ccc(/C=C/2\N=C(N(/N=C/c3cccnc3)C2=O)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A23 mock treatment 0.217 -0.00919 -1.27 0.222 -0.00394 -0.57 -1.2997 -0.9344 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 A24 positive control 0.214 -0.0122 -1.68 0.21 -0.0159 -2.3 -2.8184 -0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B01 compound treatment 0.222 -0.00419 -0.58 0.222 -0.00394 -0.57 -0.8112 -1.0 3179253 Maybridge4_001783 OC(=O)CSc1nnc([nH]1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B02 compound treatment 0.347 0.121 16.69 0.345 0.119 17.2 23.9627 0.9999 3063837 Maybridge4_001784 O=c1oc2=C(c3ccccc3)S(=O)(=O)C(=c2o1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B03 compound treatment 0.273 0.0468 6.47 0.268 0.0421 6.08 8.8692 0.9995 3179254 Maybridge4_001785 Cc1cc(C)c2c3NC(=O)CN(C(=O)c3sc2n1)c4ccccc4C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B04 compound treatment 0.222 -0.00419 -0.58 0.22 -0.00594 -0.86 -1.0155 -0.9816 1701942 Maybridge4_001786 COc1ccc(cc1)N2C(=O)Cc3ccc(OC)cc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B05 compound treatment 0.225 -0.00119 -0.16 0.226 6.25E-5 0.01 -0.1096 -0.6672 3179255 Maybridge4_001787 Clc1ccc(cc1)n2c(=N)c3cnc(nc3[nH]c2=O)N4CCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B06 compound treatment 0.266 0.0398 5.5 0.261 0.0351 5.06 7.4704 0.9992 1588538 Maybridge4_001788 Cc1oc2cc(O)ccc2c(=O)c1Oc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B07 compound treatment 0.25 0.0238 3.29 0.241 0.0151 2.18 3.8646 0.9799 3179256 Maybridge4_001789 COc1ccc(cc1)n/2c(cs\c2=N/Cc3cccnc3)c4cccc(OC)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B08 compound treatment 0.311 0.0848 11.72 0.296 0.0701 10.12 15.4412 0.9973 3179257 Maybridge4_001790 O=C(c1ccccc1)c2cccc(NC=C3C(=O)NC(=O)NC3=O)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B09 compound treatment 0.235 0.00881 1.22 0.231 0.00506 0.73 1.3779 0.9703 1289329 Maybridge4_001791 O=C1C(=C(c2ccccc2)S(=O)(=O)c3ccccc13)Cc4ccc(cc4)c5nnn[nH]5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B10 compound treatment 0.247 0.0208 2.88 0.244 0.0181 2.61 3.878 0.9988 1270319 Maybridge4_001792 O=C(c1ccccn1)c2ccc3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B11 compound treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 1356935 Maybridge4_001793 C1C2CC3CC1CC(C2)(C3)c4cn5ccccc5n4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B12 compound treatment 0.26 0.0338 4.67 0.254 0.0281 4.05 6.1693 0.9975 1489551 Maybridge4_001794 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B13 compound treatment 0.23 0.00381 0.53 0.229 0.00306 0.44 0.6852 0.9962 3063861 Maybridge4_001795 CC(=O)O[C@@H]1[C@H]2CO[C@H](O2)[C@H](OC(=O)C)[C@H]1OC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B14 compound treatment 0.25 0.0238 3.29 0.247 0.0211 3.04 4.4775 0.9992 1649672 Maybridge4_001796 COc1cc(C(=O)CCC(=O)O)c(OC)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B15 compound treatment 0.239 0.0128 1.77 0.236 0.0101 1.45 2.2794 0.9952 1471910 Maybridge4_001797 Cc1ccc(NC(=O)N2C(=O)C3(OCCO3)c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B16 compound treatment 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1205899 Maybridge4_001798 CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B17 compound treatment 0.25 0.0238 3.29 0.243 0.0171 2.46 4.0689 0.9899 3063863 Maybridge4_001799 CC(=O)Nc1ccc2oc(cc(=O)c2c1)c3ccc(C#N)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B18 compound treatment 0.296 0.0698 9.64 0.293 0.0671 9.69 13.6695 1.0 3179258 Maybridge4_001800 Cc1c(sc2nc(C)cc(C)c12)C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B19 compound treatment 0.225 -0.00119 -0.16 0.224 -0.00194 -0.28 -0.3139 -0.9676 3063864 Maybridge4_001801 CC(O)/C=C\c1cc[n+](C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B20 compound treatment 0.249 0.0228 3.15 0.246 0.0201 2.9 4.2777 0.9991 3179259 Maybridge4_001802 O=C(NC(=S)NC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B21 compound treatment 0.222 -0.00419 -0.58 0.221 -0.00494 -0.71 -0.9134 -0.9946 1176828 Maybridge4_001803 COC(=O)C1C(C(C(=O)OC)S(=O)(=O)CS1(=O)=O)c2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B22 compound treatment 0.219 -0.00719 -0.99 0.218 -0.00794 -1.15 -1.5129 -0.9974 1288189 Maybridge4_001804 COC(=O)C1=C(C)NC(=C(C1)C(=O)OC)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B23 mock treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 B24 positive control 0.225 -0.00119 -0.16 0.225 -9.38E-4 -0.14 -0.2118 -0.9955 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C01 compound treatment 0.257 0.0308 4.26 0.256 0.0301 4.34 6.0805 1.0 3179260 Maybridge4_001805 O=S(=O)(NCC1COc2ccccc2O1)c3ccc(s3)S(=O)(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C02 compound treatment 0.294 0.0678 9.37 0.303 0.0771 11.13 14.4955 0.9963 3063865 Maybridge4_001806 Fc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C03 compound treatment 0.223 -0.00319 -0.44 0.22 -0.00594 -0.86 -0.9178 -0.952 3179353 Maybridge4_001807 COc1ccc(cc1OC)C(=O)NCc2ccc(C#N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C04 compound treatment 0.287 0.0608 8.4 0.283 0.0571 8.24 11.7689 1.0 3063866 Maybridge4_001808 O=C(Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C05 compound treatment 0.215 -0.0112 -1.55 0.212 -0.0139 -2.01 -2.5164 -0.9915 3179354 Maybridge4_001809 FC(F)(F)c1ccc(cc1)c2nnc(SCc3ccncc3)n2Cc4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C06 compound treatment 0.237 0.0108 1.49 0.234 0.00806 1.16 1.8797 0.9924 3063867 Maybridge4_001810 CCOC(=O)c1nnn2c1nc(Sc3nc4ccccc4o3)c5ccccc52 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C07 compound treatment 0.227 8.12E-4 0.11 0.224 -0.00194 -0.28 -0.1185 -0.3931 3179355 Maybridge4_001811 COc1cccc(Cc2nnc(o2)c3c(C)onc3c4ccccc4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C08 compound treatment 0.345 0.119 16.41 0.339 0.113 16.33 23.1545 1.0 3179356 Maybridge4_001812 C=CCn1c(=S)sc2c(Sc3nnc(o3)c4ccco4)ncnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C09 compound treatment 0.306 0.0798 11.03 0.29 0.0641 9.25 14.3399 0.9962 3063868 Maybridge4_001813 Clc1ccc(Cn2c(=O)n(Cc3ccc(Cl)cc3)c4ccccc4c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C10 compound treatment 0.272 0.0458 6.33 0.261 0.0351 5.06 8.0565 0.9939 3179357 Maybridge4_001814 Nc1nc(SCC(=O)NC(=O)Nc2ccccc2)ncc1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C11 compound treatment 0.308 0.0818 11.3 0.287 0.0611 8.82 14.2289 0.9925 2099392 Maybridge4_001815 Cc1nc2ccc(F)cc2c3N(CCc31)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C12 compound treatment 0.418 0.192 26.5 0.406 0.18 26.01 37.129 1.0 3179358 Maybridge4_001816 C=CCSc1ncc2c(=S)[nH]c(=S)[nH]c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C13 compound treatment 0.228 0.00181 0.25 0.228 0.00206 0.3 0.3877 0.9963 3179359 Maybridge4_001817 Cc1cc(C)c2c(n1)sc3c(SCC(=O)c4ccc(Br)cc4)ncnc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C14 compound treatment 0.275 0.0488 6.74 0.271 0.0451 6.51 9.371 0.9998 3063869 Maybridge4_001818 C=CCn1nc2sc3ccccc3n2c(=O)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C15 compound treatment 0.253 0.0268 3.7 0.245 0.0191 2.75 4.5663 0.9893 3179360 Maybridge4_001819 COc1ccc(Nc2ncnc3n(Cc4ccccc4Cl)nnc23)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C16 compound treatment 0.26 0.0338 4.67 0.26 0.0341 4.92 6.7822 0.9997 3063871 Maybridge4_001820 CCOC(=O)c1c(C)c(C)sc1NC(=S)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C17 compound treatment 0.254 0.0278 3.84 0.25 0.0241 3.48 5.1746 0.9987 3179361 Maybridge4_001821 CCOC(=O)c1nnn2c1nc(N3CCN(CC3)c4ccccc4)c5ccccc52 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C18 compound treatment 0.292 0.0658 9.09 0.269 0.0431 6.22 10.8274 0.9829 3063872 Maybridge4_001822 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C19 compound treatment 0.3 0.0738 10.2 0.289 0.0631 9.11 13.6517 0.9984 3179362 Maybridge4_001823 COc1ccc(cc1)C2C(=C(N)N3CCc4cc(OC)c(OC)cc4C3=C2C#N)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C20 compound treatment 0.249 0.0228 3.15 0.243 0.0171 2.46 3.9712 0.9926 3063873 Maybridge4_001824 CNC(=O)NC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C21 compound treatment 0.286 0.0598 8.26 0.279 0.0531 7.66 11.2627 0.9993 3179363 Maybridge4_001825 COc1cc2CCN3C(N(N=C3C(=O)c4cccs4)c5ccccc5)c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C22 compound treatment 0.272 0.0458 6.33 0.26 0.0341 4.92 7.9544 0.9922 3063874 Maybridge4_001826 Fc1ccc(/C=N/N2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C23 mock treatment 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 C24 positive control 0.228 0.00181 0.25 0.227 0.00106 0.15 0.2856 0.9724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D01 compound treatment 0.261 0.0348 4.81 0.26 0.0341 4.92 6.8798 0.9999 3179364 Maybridge4_001827 CCOC(=O)CSc1nc(Nc2ccc(OC)cc2)c3cnc(nc3n1)N(CC)CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D02 compound treatment 0.224 -0.00219 -0.3 0.219 -0.00694 -1.0 -0.9223 -0.8812 1016783 Maybridge4_001828 CSc1ncnc2[nH]cnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D03 compound treatment 0.282 0.0558 7.71 0.275 0.0491 7.09 10.4634 0.9991 3179365 Maybridge4_001829 CCOC(=O)CSc1nc(Nc2ccccc2)c3cnc(nc3n1)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D04 compound treatment 0.224 -0.00219 -0.3 0.222 -0.00394 -0.57 -0.6159 -0.9562 3063875 Maybridge4_001830 CCn1c(C)[n+](CC)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D05 compound treatment 0.248 0.0218 3.01 0.241 0.0151 2.18 3.6693 0.9872 3179366 Maybridge4_001831 Nc1c(C#N)c(cc2c3ccccc3oc(=O)c12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D06 compound treatment 0.231 0.00481 0.66 0.227 0.00106 0.15 0.5786 0.848 1156367 Maybridge4_001832 CC(=O)Oc1ccc2c(=O)c(Oc3ccc(Cl)cc3)c(C)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D07 compound treatment 0.239 0.0128 1.77 0.236 0.0101 1.45 2.2794 0.9952 3179367 Maybridge4_001833 CC(/C=N/N1C(=O)c2ccccc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D08 compound treatment 0.391 0.165 22.77 0.401 0.175 25.29 33.9807 0.9986 3063876 Maybridge4_001834 COC(=O)c1sc(=S)sc1C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D09 compound treatment 0.247 0.0208 2.88 0.245 0.0191 2.75 3.9801 0.9998 1027030 Maybridge4_001835 Clc1ccc2OC(CC(=O)c2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D10 compound treatment 0.22 -0.00619 -0.85 0.216 -0.00994 -1.44 -1.6194 -0.9693 1567173 Maybridge4_001836 C=CCN1C(=O)NC2(CCCCC2)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D11 compound treatment 0.282 0.0558 7.71 0.27 0.0441 6.36 9.9527 0.9955 1014811 Maybridge4_001837 O=C(N(C(=O)c1ccccc1)C(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D12 compound treatment 0.223 -0.00319 -0.44 0.223 -0.00294 -0.42 -0.6114 -0.9998 1422860 Maybridge4_001838 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D13 compound treatment 0.225 -0.00119 -0.16 0.223 -0.00294 -0.42 -0.416 -0.9145 3063327 Maybridge4_001839 CCOc1ccc2nc(S/C=C/C(=O)c3ccc(Cl)cc3)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D14 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 1403045 Maybridge4_001840 COc1cc(c(OC)cc1C)c2cc(OC)c(C)cc2OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D15 compound treatment 0.217 -0.00919 -1.27 0.216 -0.00994 -1.44 -1.9125 -0.9981 1267535 Maybridge4_001841 OC(=O)C(Sc1ccccc1C(=O)O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D16 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 3063328 Maybridge4_001842 CC(C)(C)[C@H]1COC(=N1)CC2=N[C@H](CO2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D17 compound treatment 0.317 0.0908 12.55 0.32 0.0941 13.59 18.4787 0.9992 1035033 Maybridge4_001843 O=C(C1=NNCC1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D18 compound treatment 0.31 0.0838 11.58 0.303 0.0771 11.13 16.0585 0.9998 1414609 Maybridge4_001844 CC(=O)Oc1ccc2c(=O)c(c3nc4ccccc4n3C)c(C)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D19 compound treatment 0.22 -0.00619 -0.85 0.218 -0.00794 -1.15 -1.4152 -0.9895 3063329 Maybridge4_001845 CC1=CC(=O)OC(C1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D20 compound treatment 0.288 0.0618 8.54 0.282 0.0561 8.1 11.7645 0.9996 1054135 Maybridge4_001846 CCc1c(O)nc2ccccn2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D21 compound treatment 0.221 -0.00519 -0.72 0.22 -0.00594 -0.86 -1.1132 -0.996 1416442 Maybridge4_001847 CCN(CC)CCC1S(=O)(=O)CC(CS1(=O)=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D22 compound treatment 0.231 0.00481 0.66 0.223 -0.00294 -0.42 0.1701 0.2157 3179368 Maybridge4_001848 C(/N=C/c1cn(nc1c2ccccc2)c3ccccc3)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D23 mock treatment 0.228 0.00181 0.25 0.227 0.00106 0.15 0.2856 0.9724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 D24 positive control 0.228 0.00181 0.25 0.227 0.00106 0.15 0.2856 0.9724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E01 compound treatment 0.224 -0.00219 -0.3 0.225 -9.38E-4 -0.14 -0.3094 -0.9344 3063330 Maybridge4_001849 O=C(Nc1cccs1)N2CCN(CC2)C(=O)C3CCCO3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E02 compound treatment 0.307 0.0808 11.16 0.295 0.0691 9.98 14.9483 0.9984 3179369 Maybridge4_001850 Clc1ccc(NC(=O)N2N=C3C(CCc4ccccc34)C2c5cccs5)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E03 compound treatment 0.257 0.0308 4.26 0.256 0.0301 4.34 6.0805 1.0 3063331 Maybridge4_001851 CC(C)(C)c1cc(C(=O)NCc2ccc(C#N)cc2)n(Cc3ccccc3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E04 compound treatment 0.3 0.0738 10.2 0.315 0.0891 12.86 16.3073 0.9934 3179370 Maybridge4_001852 C1Cc2ccccc2N1c3nnc(c4ccccc4)c(n3)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E05 compound treatment 0.238 0.0118 1.63 0.234 0.00806 1.16 1.9774 0.9863 3179371 Maybridge4_001853 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)N3CCCN(CC3)C(=O)OC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E06 compound treatment 0.225 -0.00119 -0.16 0.224 -0.00194 -0.28 -0.3139 -0.9676 3063332 Maybridge4_001854 CCOC(=O)c1nnn2c1nc(Sc3nnc(c4ccncc4)n3C)c5ccccc52 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E07 compound treatment 0.221 -0.00519 -0.72 0.225 -9.38E-4 -0.14 -0.6025 -0.8261 3179372 Maybridge4_001855 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)C(=O)OC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E08 compound treatment 0.232 0.00581 0.8 0.231 0.00506 0.73 1.0849 0.9989 1566406 Maybridge4_001856 CNc1nc(=S)[nH]c2sc3CCCCc3c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E09 compound treatment 0.222 -0.00419 -0.58 0.218 -0.00794 -1.15 -1.2198 -0.9498 3179373 Maybridge4_001857 OC[C@@H]1O[C@@H](C[C@H]1O)n2cnc3c(=O)[nH]cnc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E10 compound treatment 0.27 0.0438 6.05 0.265 0.0391 5.64 8.2697 0.9994 3063334 Maybridge4_001858 COc1ccc(Nc2ncc(C#N)c(N)n2)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E11 compound treatment 0.238 0.0118 1.63 0.24 0.0141 2.03 2.5903 0.9941 3179374 Maybridge4_001859 CCNc1nc(=S)[nH]c2n(ncc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E12 compound treatment 0.319 0.0928 12.82 0.321 0.0951 13.73 18.7762 0.9994 3063335 Maybridge4_001860 CCN(CC)c1ncc2c(=S)[nH]c(=S)[nH]c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E13 compound treatment 0.242 0.0158 2.18 0.234 0.00806 1.16 2.3682 0.9566 3179375 Maybridge4_001861 Cc1cc(C)c2c(n1)sc3c(Sc4nnc(o4)c5ccncc5)ncnc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E14 compound treatment 0.276 0.0498 6.88 0.26 0.0341 4.92 8.3452 0.9865 3179376 Maybridge4_001862 CCOC(=O)N1CCc2c(C1)sc3ncn(Cc4ccc(Cl)cc4)c(=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E15 compound treatment 0.363 0.137 18.9 0.365 0.139 20.09 27.5685 0.9995 3063336 Maybridge4_001863 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=S)NCC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E16 compound treatment 0.231 0.00481 0.66 0.23 0.00406 0.59 0.8851 0.9981 1616264 Maybridge4_001864 CC1=NN(C(=O)C1)c2ncnc3sc4CCCCc4c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E17 compound treatment 0.248 0.0218 3.01 0.251 0.0251 3.62 4.6907 0.9958 3179377 Maybridge4_001865 CCOC(=O)c1nnn2c1nc(N(Cc3ccccc3)Cc4ccccc4)c5ccccc52 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E18 compound treatment 0.226 -1.88E-4 -0.03 0.228 0.00206 0.3 0.1923 0.6432 3063337 Maybridge4_001866 NNC(=O)/C(=C\c1ccccc1)/NC(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E19 compound treatment 0.336 0.11 15.17 0.318 0.0921 13.3 20.1304 0.9978 3179378 Maybridge4_001867 Cc1ccc(Cc2nn3c(nn(c4ccc(Cl)cc4)c3nc2=O)C(=O)c5cccs5)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E20 compound treatment 0.23 0.00381 0.53 0.226 6.25E-5 0.01 0.3788 0.7191 3063338 Maybridge4_001868 Fc1ccc(Cn2nc3CSc4ccccc4-n3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E21 compound treatment 0.305 0.0788 10.89 0.296 0.0701 10.12 14.8551 0.9993 3063339 Maybridge4_001869 Cc1ccc2nc(C)c3CCN(c3c2c1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E22 compound treatment 0.331 0.105 14.48 0.333 0.107 15.46 21.1741 0.9995 3179379 Maybridge4_001870 Fc1ccc(/C=C\2/N=C(N(CC(=O)c3ccco3)C2=O)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E23 mock treatment 0.225 -0.00119 -0.16 0.224 -0.00194 -0.28 -0.3139 -0.9676 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 E24 positive control 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F01 compound treatment 0.26 0.0338 4.67 0.278 0.0521 7.52 8.6206 0.9738 3179475 Maybridge4_001871 Cc1cc(nc2oc3C(=O)N(CC(=O)Nc3c12)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F02 compound treatment 0.214 -0.0122 -1.68 0.218 -0.00794 -1.15 -2.0013 -0.9825 1429948 Maybridge4_001872 CC1(C)C(NC(=O)C2CCCCC2)[C@]3(C)CCC1C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F03 compound treatment 0.296 0.0698 9.64 0.294 0.0681 9.83 13.7716 1.0 3179476 Maybridge4_001873 CCN(CC)c1ncc2c(NCc3ccccc3)nc(SCc4ccccc4)nc2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F04 compound treatment 0.219 -0.00719 -0.99 0.22 -0.00594 -0.86 -1.3086 -0.9973 1050962 Maybridge4_001874 NC(=O)CCCCC1CCSS1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F05 compound treatment 0.223 -0.00319 -0.44 0.226 6.25E-5 0.01 -0.305 -0.6925 3179477 Maybridge4_001875 O=C(CN1CCc2ccccc12)Nc3scc4c3c(=O)oc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F06 compound treatment 0.238 0.0118 1.63 0.238 0.0121 1.74 2.386 0.9995 3063341 Maybridge4_001876 CC1(C)C2CCC1(C)c3noc(c23)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F07 compound treatment 0.22 -0.00619 -0.85 0.221 -0.00494 -0.71 -1.1088 -0.9959 1040822 Maybridge4_001877 Cc1ccc(NC(=O)N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F08 compound treatment 0.243 0.0168 2.32 0.245 0.0191 2.75 3.5894 0.9964 1502018 Maybridge4_001878 COc1ccc2oc(cc(=O)c2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F09 compound treatment 0.384 0.158 21.8 0.383 0.157 22.69 31.4584 0.9998 3063363 Maybridge4_001879 O=C1/C(=C/c2ccc(cc2)c3nnn[nH]3)/C(Oc4ccccc14)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F10 compound treatment 0.218 -0.00819 -1.13 0.216 -0.00994 -1.44 -1.8148 -0.993 3063364 Maybridge4_001880 CC1(C)NC(=O)N(CC=C)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F11 compound treatment 0.259 0.0328 4.53 0.254 0.0281 4.05 6.0716 0.9984 3063365 Maybridge4_001881 Clc1ccccc1CNC(=S)NC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F12 compound treatment 0.231 0.00481 0.66 0.232 0.00606 0.88 1.0893 0.9908 3063366 Maybridge4_001882 Fc1ccc(cc1)N(Cc2ccc(Br)cc2)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F13 compound treatment 0.229 0.00281 0.39 0.228 0.00206 0.3 0.4854 0.9914 1687915 Maybridge4_001883 CC1(C)CC(=O)C=C(C1)Sc2nc3ccccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F14 compound treatment 0.221 -0.00519 -0.72 0.222 -0.00394 -0.57 -0.9089 -0.9934 3063367 Maybridge4_001884 C[n+]1ccc(CCc2cc[n+](C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F15 compound treatment 0.22 -0.00619 -0.85 0.22 -0.00594 -0.86 -1.2109 -1.0 1612566 Maybridge4_001885 CCC(=O)N1N(C(=O)CC)c2cc(Cl)ccc2-n3c1nn(C(=O)CC)c3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F16 compound treatment 0.277 0.0508 7.02 0.273 0.0471 6.8 9.7706 0.9999 1406161 Maybridge4_001886 CC(=O)Oc1c(I)c(=O)n(C)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F17 compound treatment 0.228 0.00181 0.25 0.224 -0.00194 -0.28 -0.0208 -0.0555 3179478 Maybridge4_001887 CCSC(=O)NC1CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F18 compound treatment 0.242 0.0158 2.18 0.237 0.0111 1.6 2.6746 0.9882 3179479 Maybridge4_001888 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F19 compound treatment 0.301 0.0748 10.34 0.289 0.0631 9.11 13.7494 0.998 1002179 Maybridge4_001889 Clc1ccc(cc1)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F20 compound treatment 0.248 0.0218 3.01 0.244 0.0181 2.61 3.9757 0.9974 3063368 Maybridge4_001890 CCC(C)Sc1nnc(S)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F21 compound treatment 0.224 -0.00219 -0.3 0.221 -0.00494 -0.71 -0.718 -0.9269 3179480 Maybridge4_001891 COC(=O)/C(=C/c1ccccc1)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F22 compound treatment 0.23 0.00381 0.53 0.228 0.00206 0.3 0.5831 0.9636 1172572 Maybridge4_001892 O=c1[nH]cc(NCc2ccccc2)c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F23 mock treatment 0.224 -0.00219 -0.3 0.223 -0.00294 -0.42 -0.5137 -0.9862 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 F24 positive control 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G01 compound treatment 0.222 -0.00419 -0.58 0.222 -0.00394 -0.57 -0.8112 -1.0 3179481 Maybridge4_001893 CCOC(=O)N1CCC(CC1)NC(=O)CCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G02 compound treatment 0.245 0.0188 2.6 0.246 0.0201 2.9 3.8869 0.9985 3179482 Maybridge4_001894 O=C1CSC2=NC3=C(CCc4ccccc34)C(N12)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G03 compound treatment 0.216 -0.0102 -1.41 0.22 -0.00594 -0.86 -1.6016 -0.9718 3063369 Maybridge4_001895 CCOC(=O)c1ncn(Cc2ccccc2)c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G04 compound treatment 0.22 -0.00619 -0.85 0.222 -0.00394 -0.57 -1.0066 -0.9804 3063370 Maybridge4_001896 S=c1[nH]nc(Cn2nnc3ccccc23)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G05 compound treatment 0.308 0.0818 11.3 0.288 0.0621 8.96 14.331 0.9934 3179483 Maybridge4_001897 COc1cccc(Cc2nnc(o2)c3ccc(s3)c4cccs4)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G06 compound treatment 0.262 0.0358 4.95 0.264 0.0381 5.5 7.3861 0.9986 3063371 Maybridge4_001898 Cn1nc2c3ccccc3n(Cc4ccccc4)c2nc1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G07 compound treatment 0.231 0.00481 0.66 0.238 0.0121 1.74 1.7022 0.9127 3179484 Maybridge4_001899 CCOC(=O)c1cnn(C(=O)Cc2cccc(OC)c2)c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G08 compound treatment 0.246 0.0198 2.74 0.245 0.0191 2.75 3.8824 1.0 1696254 Maybridge4_001900 COc1cc(OC)c2nc(C)c3CCSc3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G09 compound treatment 0.232 0.00581 0.8 0.228 0.00206 0.3 0.7785 0.9089 3179485 Maybridge4_001901 CC(=O)Nc1ccccc1OCC2CC(=NO2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G10 compound treatment 0.279 0.0528 7.3 0.281 0.0551 7.95 10.7831 0.9991 3179486 Maybridge4_001902 C1Sc2nnc(c3ccccc3)n2N=C1c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G11 compound treatment 0.263 0.0368 5.09 0.258 0.0321 4.63 6.8709 0.9989 3063373 Maybridge4_001903 S=c1nc(Nc2ccccc2)c3cnn(c4ccccc4)c3[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G12 compound treatment 0.264 0.0378 5.22 0.264 0.0381 5.5 7.5815 0.9997 3179487 Maybridge4_001904 CN1CCN(CC1)c2ncc3c(=S)[nH]c(=S)[nH]c3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G13 compound treatment 0.233 0.00681 0.94 0.236 0.0101 1.45 1.6933 0.9779 3063374 Maybridge4_001905 CCn1c(Sc2ncnc3c2sc4nc(C)cc(C)c43)nnc1c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G14 compound treatment 0.226 -1.88E-4 -0.03 0.227 0.00106 0.15 0.0902 0.5796 3179488 Maybridge4_001906 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=S)N3CCc4ccccc34)sc2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G15 compound treatment 0.32 0.0938 12.96 0.313 0.0871 12.58 18.0567 0.9999 3179489 Maybridge4_001907 CCNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G16 compound treatment 0.226 -1.88E-4 -0.03 0.226 6.25E-5 0.01 -0.0119 -0.435 1303898 Maybridge4_001908 CC1=NN(C(=O)C1)c2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G17 compound treatment 0.247 0.0208 2.88 0.246 0.0201 2.9 4.0823 1.0 3063375 Maybridge4_001909 CCOC(=O)C1=NN(C2N1CCc3cc(OC)c(OC)cc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G18 compound treatment 0.28 0.0538 7.43 0.279 0.0531 7.66 10.6765 0.9999 3179490 Maybridge4_001910 COc1cc(/C=C\2/N=C(N(C)C2=O)c3ccccc3)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G19 compound treatment 0.27 0.0438 6.05 0.26 0.0341 4.92 7.759 0.9947 3063377 Maybridge4_001911 Cc1c(C)c(=O)n(Cc2ccc(Br)cc2)c(=O)n1Cc3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G20 compound treatment 0.258 0.0318 4.39 0.254 0.0281 4.05 5.9739 0.9992 3179491 Maybridge4_001912 O=C(Cn1nc2CSc3ccccc3-n2c1=O)NC(=O)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G21 compound treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 3179492 Maybridge4_001913 CCOC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)Nc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G22 compound treatment 0.303 0.0768 10.61 0.315 0.0891 12.86 16.6003 0.9954 1150256 Maybridge4_001914 N(c1ccccc1)c2ncnc3sc(cc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G23 mock treatment 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 G24 positive control 0.225 -0.00119 -0.16 0.224 -0.00194 -0.28 -0.3139 -0.9676 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H01 compound treatment 0.226 -1.88E-4 -0.03 0.225 -9.38E-4 -0.14 -0.1141 -0.8274 3179493 Maybridge4_001915 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)c3ccco3)n2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H02 compound treatment 0.232 0.00581 0.8 0.232 0.00606 0.88 1.187 0.9991 1202312 Maybridge4_001916 Clc1ccc(OC2CN(C2)C(=O)N3CC(C3)Oc4ccc(Cl)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H03 compound treatment 0.285 0.0588 8.13 0.254 0.0281 4.05 8.6115 0.9484 3179494 Maybridge4_001917 O=C(CN1CCc2ccccc12)Nc3nnc(s3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H04 compound treatment 0.222 -0.00419 -0.58 0.25 0.0241 3.48 2.0486 0.5814 1178262 Maybridge4_001918 COc1ccc(cc1)c2nc3cc4Nc5ccccc5Oc4cc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H05 compound treatment 0.257 0.0308 4.26 0.255 0.0291 4.2 5.9784 1.0 3063402 Maybridge4_001919 O=C(Nc1scc2c1c(=O)oc3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H06 compound treatment 0.221 -0.00519 -0.72 0.22 -0.00594 -0.86 -1.1132 -0.996 3179495 Maybridge4_001920 FC(F)(F)C(NC(=O)c1cccnc1)(N2CCCC2=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H07 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 1117011 Maybridge4_001921 COc1cccc(NC(=O)N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H08 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 3063403 Maybridge4_001922 NC(=O)c1cc(Cl)c(Cl)cc1C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H09 compound treatment 0.251 0.0248 3.43 0.24 0.0141 2.03 3.8602 0.9688 3179496 Maybridge4_001923 O[C@H]1[C@@H](Oc2ccccc2C1=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H10 compound treatment 0.221 -0.00519 -0.72 0.22 -0.00594 -0.86 -1.1132 -0.996 3063404 Maybridge4_001924 COc1ncnc(OC)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H11 compound treatment 0.329 0.103 14.2 0.33 0.104 15.03 20.6723 0.9996 1558852 Maybridge4_001925 CC1=C(C(C2=C(N1)c3ccccc3C2=O)c4ccccc4)C(=O)Nc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H12 compound treatment 0.221 -0.00519 -0.72 0.221 -0.00494 -0.71 -1.0111 -1.0 1698244 Maybridge4_001926 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H13 compound treatment 0.225 -0.00119 -0.16 0.226 6.25E-5 0.01 -0.1096 -0.6672 1372400 Maybridge4_001927 O=c1c(c[nH]c2ccccc12)c3nnnn3c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H14 compound treatment 0.22 -0.00619 -0.85 0.219 -0.00694 -1.0 -1.313 -0.9969 3179497 Maybridge4_001928 N1[C@H]([C@H](N=C1c2ccccc2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H15 compound treatment 0.216 -0.0102 -1.41 0.217 -0.00894 -1.29 -1.9081 -0.9991 3063405 Maybridge4_001929 CO[C@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1OC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H16 compound treatment 0.222 -0.00419 -0.58 0.222 -0.00394 -0.57 -0.8112 -1.0 1081881 Maybridge4_001930 COC(=O)CSc1nc2ccccc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H17 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 3063406 Maybridge4_001931 CC(C)N(C(C)C)C(=O)NCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H18 compound treatment 0.249 0.0228 3.15 0.245 0.0191 2.75 4.1755 0.9977 3179498 Maybridge4_001932 Clc1ccc(cc1)c2nc(SCc3ccccc3)[nH]c(=S)c2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H19 compound treatment 0.22 -0.00619 -0.85 0.221 -0.00494 -0.71 -1.1088 -0.9959 3063407 Maybridge4_001933 OC(=O)c1cc(F)cc(c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H20 compound treatment 0.217 -0.00919 -1.27 0.217 -0.00894 -1.29 -1.8104 -1.0 1198061 Maybridge4_001934 CC(Oc1ccc(Cl)cc1Cl)c2n[nH]c(=S)n2CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H21 compound treatment 0.219 -0.00719 -0.99 0.218 -0.00794 -1.15 -1.5129 -0.9974 3179499 Maybridge4_001935 FC(F)(F)C(NC1CCCCC1)(NC(=O)c2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H22 compound treatment 0.279 0.0528 7.3 0.27 0.0441 6.36 9.6596 0.9977 1345621 Maybridge4_001936 O=c1[nH][nH]c(=O)n1CCCc2cc3cccc4ccc5cccc2c5c43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H23 mock treatment 0.229 0.00281 0.39 0.23 0.00406 0.59 0.6897 0.98 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 H24 positive control 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I01 compound treatment 0.247 0.0208 2.88 0.246 0.0201 2.9 4.0823 1.0 3179500 Maybridge4_001937 NC(=O)c1ccccc1NCC(=O)c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I02 compound treatment 0.219 -0.00719 -0.99 0.218 -0.00794 -1.15 -1.5129 -0.9974 1786031 Maybridge4_001938 S=c1[nH]nc(Cc2ccccc2)n1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I03 compound treatment 0.22 -0.00619 -0.85 0.219 -0.00694 -1.0 -1.313 -0.9969 1416652 Maybridge4_001939 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I04 compound treatment 0.216 -0.0102 -1.41 0.215 -0.0109 -1.58 -2.1123 -0.9983 3179586 Maybridge4_001940 CNC(=O)NC(=O)CSc1nnc(Cc2ccccc2)n1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I05 compound treatment 0.235 0.00881 1.22 0.233 0.00706 1.02 1.5822 0.9961 3063409 Maybridge4_001941 Cn1cc(cn1)S(=O)(=O)Nc2ccc(Oc3c(Cl)cccc3Cl)nc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I06 compound treatment 0.232 0.00581 0.8 0.226 6.25E-5 0.01 0.5742 0.715 3179587 Maybridge4_001942 Clc1ccccc1CC(C(=O)N2CCc3ccccc23)C(=O)N4CCc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I07 compound treatment 0.271 0.0448 6.19 0.264 0.0381 5.5 8.2653 0.9982 3063410 Maybridge4_001943 CCOC(=O)c1cnn(C(=O)c2ccc(cc2)n3c(C)ccc3C)c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I08 compound treatment 0.264 0.0378 5.22 0.259 0.0331 4.78 7.0708 0.999 1500802 Maybridge4_001944 NC(=O)c1nnc2ccc(Cl)cc2c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I09 compound treatment 0.235 0.00881 1.22 0.234 0.00806 1.16 1.6844 0.9998 1103360 Maybridge4_001945 FC(F)(F)c1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I10 compound treatment 0.227 8.12E-4 0.11 0.224 -0.00194 -0.28 -0.1185 -0.3931 3179588 Maybridge4_001946 O=C(CSc1nnc2NCCCn12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I11 compound treatment 0.286 0.0598 8.26 0.282 0.0561 8.1 11.5691 0.9999 1721477 Maybridge4_001947 Cc1nn(c2NC3=C(C(c12)c4cccnc4)C(=O)CC(C)(C)C3)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I12 compound treatment 0.229 0.00281 0.39 0.227 0.00106 0.15 0.3833 0.9174 1444715 Maybridge4_001948 Cc1nc2cc(C)ccn2c1c3nnco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I13 compound treatment 0.227 8.12E-4 0.11 0.224 -0.00194 -0.28 -0.1185 -0.3931 3063411 Maybridge4_001949 Cc1cc(C)c(C#N)c(Sc2ncnc3c2sc4nc(C)cc(C)c43)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I14 compound treatment 0.227 8.12E-4 0.11 0.224 -0.00194 -0.28 -0.1185 -0.3931 3179589 Maybridge4_001950 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I15 compound treatment 0.331 0.105 14.48 0.327 0.101 14.6 20.5612 1.0 3179590 Maybridge4_001951 CNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I16 compound treatment 0.314 0.0878 12.13 0.311 0.0851 12.29 17.2663 1.0 3063412 Maybridge4_001952 CCOC(=O)N1CCc2c(C1)sc3[nH]c(=S)n(c4ccccc4)c(=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I17 compound treatment 0.229 0.00281 0.39 0.228 0.00206 0.3 0.4854 0.9914 3179591 Maybridge4_001953 COc1cc2CCn3c(C(=O)c4cccs4)c(c(C#N)c3-c2cc1OC)c5ccc(C)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I18 compound treatment 0.336 0.11 15.17 0.341 0.115 16.62 22.4796 0.999 3063413 Maybridge4_001954 Fc1ccc(CN2C(=O)/C(=C\c3ccc(F)cc3)/N=C2c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I19 compound treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 3179592 Maybridge4_001955 CCC(C)[C@H](NC(=O)c1ccco1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I20 compound treatment 0.331 0.105 14.48 0.329 0.103 14.89 20.7655 0.9999 3179593 Maybridge4_001956 COc1cccc(c1)C(=O)c2sc3nsc(SCc4ccccc4)c3c2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I21 compound treatment 0.222 -0.00419 -0.58 0.222 -0.00394 -0.57 -0.8112 -1.0 3063414 Maybridge4_001957 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCC(=O)c4ccccc4)n3CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I22 compound treatment 0.223 -0.00319 -0.44 0.221 -0.00494 -0.71 -0.8157 -0.9731 3179594 Maybridge4_001958 C=CCn1nc2CSc3ccccc3-n2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I23 mock treatment 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 I24 positive control 0.222 -0.00419 -0.58 0.222 -0.00394 -0.57 -0.8112 -1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J01 compound treatment 0.229 0.00281 0.39 0.23 0.00406 0.59 0.6897 0.98 3179595 Maybridge4_001959 CCOC(=O)CSc1nc(CN2c3ccccc3Sc4ccccc24)n[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J02 compound treatment 0.23 0.00381 0.53 0.226 6.25E-5 0.01 0.3788 0.7191 1402836 Maybridge4_001960 NS(=O)(=O)c1ccc(Cl)cc1Sc2ccccc2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J03 compound treatment 0.219 -0.00719 -0.99 0.216 -0.00994 -1.44 -1.7171 -0.9838 3179596 Maybridge4_001961 CCOC(=O)Cn1c(nc(c1c2ccccc2)c3ccccc3)c4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J04 compound treatment 0.229 0.00281 0.39 0.224 -0.00194 -0.28 0.0769 0.1605 1114912 Maybridge4_001962 NNC(=O)CNC(=O)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J05 compound treatment 0.247 0.0208 2.88 0.262 0.0361 5.21 5.7165 0.9608 3179597 Maybridge4_001963 Fc1ccc(COc2nc(cc(c3ccco3)c2C#N)c4cccs4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J06 compound treatment 0.233 0.00681 0.94 0.228 0.00206 0.3 0.8762 0.8875 3063348 Maybridge4_001964 FC(F)(F)C(NCc1ccccn1)(NC(=O)c2cccnc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J07 compound treatment 0.291 0.0648 8.95 0.288 0.0621 8.96 12.6703 1.0 3179598 Maybridge4_001965 COc1ccc(/N=C/c2cn(cc2\C=N\c3ccc(OC)cc3)c4ccc(OC)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J08 compound treatment 0.231 0.00481 0.66 0.226 6.25E-5 0.01 0.4765 0.7166 1550362 Maybridge4_001966 OC(=O)c1ccccc1NC(=O)OCC2c3ccccc3-c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J09 compound treatment 0.249 0.0228 3.15 0.247 0.0211 3.04 4.3798 0.9998 3179599 Maybridge4_001967 CC1(C)CC(=O)C=C(C1)Sc2nc3cc(Cl)ccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J10 compound treatment 0.229 0.00281 0.39 0.224 -0.00194 -0.28 0.0769 0.1605 1156147 Maybridge4_001968 COc1ccc2nc3n(C)c(=O)n(C)c(=O)c3cc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J11 compound treatment 0.285 0.0588 8.13 0.278 0.0521 7.52 11.0628 0.9993 3179600 Maybridge4_001969 O=C1C2=C(NC(=S)NC2c3ccccc3)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J12 compound treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 1727811 Maybridge4_001970 COc1cc(CCC(C)NC(=O)c2ccco2)ccc1OC(=O)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J13 compound treatment 0.229 0.00281 0.39 0.228 0.00206 0.3 0.4854 0.9914 3063350 Maybridge4_001971 COc1ccc(C#N)cc1Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J14 compound treatment 0.225 -0.00119 -0.16 0.223 -0.00294 -0.42 -0.416 -0.9145 1014022 Maybridge4_001972 O=S(=O)(Cc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J15 compound treatment 0.222 -0.00419 -0.58 0.221 -0.00494 -0.71 -0.9134 -0.9946 3179601 Maybridge4_001973 Nc1n/c(=N\c2ccccc2)/n(c3ccccc3)c(=N)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J16 compound treatment 0.236 0.00981 1.36 0.231 0.00506 0.73 1.4756 0.958 3063351 Maybridge4_001974 FC(F)(F)c1ccccc1/N=C/2\CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J17 compound treatment 0.226 -1.88E-4 -0.03 0.224 -0.00194 -0.28 -0.2162 -0.7693 3179602 Maybridge4_001975 COCOc1ccc(cc1OC)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J18 compound treatment 0.243 0.0168 2.32 0.243 0.0171 2.46 3.3851 0.9996 1465673 Maybridge4_001976 CC(Nc1ccccc1)(C#N)c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J19 compound treatment 0.265 0.0388 5.36 0.254 0.0281 4.05 6.6578 0.9905 3179603 Maybridge4_001977 c1ccc(cc1)c2nnc(o2)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J20 compound treatment 0.222 -0.00419 -0.58 0.223 -0.00294 -0.42 -0.7091 -0.9884 1519121 Maybridge4_001978 CC(Oc1ccccc1c2ccccc2)c3n[nH]c(=S)n3c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J21 compound treatment 0.224 -0.00219 -0.3 0.223 -0.00294 -0.42 -0.5137 -0.9862 3063353 Maybridge4_001979 COC(NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J22 compound treatment 0.218 -0.00819 -1.13 0.217 -0.00894 -1.29 -1.7127 -0.9978 1009264 Maybridge4_001980 CC(NC(=O)C)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J23 mock treatment 0.229 0.00281 0.39 0.23 0.00406 0.59 0.6897 0.98 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 J24 positive control 0.228 0.00181 0.25 0.229 0.00306 0.44 0.4899 0.9637 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K01 compound treatment 0.227 8.12E-4 0.11 0.229 0.00306 0.44 0.3922 0.8593 3179604 Maybridge4_001981 OC(=O)CSCC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K02 compound treatment 0.241 0.0148 2.05 0.239 0.0131 1.89 2.7812 0.9992 3063380 Maybridge4_001982 CCOC(=O)c1nnn2c1nc(SCC(=O)N)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K03 compound treatment 0.222 -0.00419 -0.58 0.223 -0.00294 -0.42 -0.7091 -0.9884 3179605 Maybridge4_001983 COc1ccc(NC(=O)c2ccc(CN3CCS(=O)(=O)CC3)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K04 compound treatment 0.223 -0.00319 -0.44 0.225 -9.38E-4 -0.14 -0.4071 -0.8837 3063381 Maybridge4_001984 CNC(=O)NC(=O)CSc1nnc(c2ccncc2)n1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K05 compound treatment 0.227 8.12E-4 0.11 0.227 0.00106 0.15 0.1879 0.9882 3179606 Maybridge4_001985 S=C(NCC1CC(=NO1)c2ccccc2)NCc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K06 compound treatment 0.229 0.00281 0.39 0.23 0.00406 0.59 0.6897 0.98 3179607 Maybridge4_001986 CCOc1nc-2c(Cc3ccccc32)c(c4ccco4)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K07 compound treatment 0.228 0.00181 0.25 0.226 6.25E-5 0.01 0.1834 0.7321 3063383 Maybridge4_001987 Sc1nnc(Cc2ccsc2)n1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K08 compound treatment 0.28 0.0538 7.43 0.279 0.0531 7.66 10.6765 0.9999 3179608 Maybridge4_001988 O=c1[nH]c-2c(CCc3ccccc32)c(c1C#N)c4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K09 compound treatment 0.243 0.0168 2.32 0.245 0.0191 2.75 3.5894 0.9964 3063384 Maybridge4_001989 C=CCSc1c2CCCc2c(C#N)c3nc4ccccc4n13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K10 compound treatment 0.229 0.00281 0.39 0.228 0.00206 0.3 0.4854 0.9914 3179609 Maybridge4_001990 O=C(N1CCCn2c(SCc3ccccc3)nnc12)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K11 compound treatment 0.284 0.0578 7.99 0.293 0.0671 9.69 12.4972 0.9954 3063386 Maybridge4_001991 CCNC(=S)Nc1sc2CC(C)CCc2c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K12 compound treatment 0.245 0.0188 2.6 0.241 0.0151 2.18 3.3762 0.9961 3179610 Maybridge4_001992 Cc1sc2nc3SCC(=Nn3c(=O)c2c1C)c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K13 compound treatment 0.28 0.0538 7.43 0.277 0.0511 7.38 10.4723 1.0 3063387 Maybridge4_001993 CCOC(=O)c1oc2nc(cc(c3ccco3)c2c1N)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K14 compound treatment 0.224 -0.00219 -0.3 0.224 -0.00194 -0.28 -0.4116 -0.9993 3179611 Maybridge4_001994 C1Sc2ccccc2-n3c(nnc13)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K15 compound treatment 0.221 -0.00519 -0.72 0.224 -0.00194 -0.28 -0.7046 -0.9159 3179694 Maybridge4_001995 CCOC(=O)c1nnn2c1n(C)c(=O)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K16 compound treatment 0.273 0.0468 6.47 0.272 0.0461 6.65 9.2778 0.9999 3063389 Maybridge4_001996 O=c1c(nnc2sc3ccccc3n12)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K17 compound treatment 0.249 0.0228 3.15 0.241 0.0151 2.18 3.767 0.9836 3179695 Maybridge4_001997 CCOC(=O)C1=NN(C2C1c3cccc4cccc2c34)c5ccc(C)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K18 compound treatment 0.281 0.0548 7.57 0.278 0.0521 7.52 10.6721 1.0 3063390 Maybridge4_001998 Clc1ccccc1/C=C\2/N=C(N(CC=C)C2=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K19 compound treatment 0.232 0.00581 0.8 0.229 0.00306 0.44 0.8806 0.9605 3179696 Maybridge4_001999 O=C(NCC1COc2ccccc2O1)Nc3csc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K20 compound treatment 0.225 -0.00119 -0.16 0.225 -9.38E-4 -0.14 -0.2118 -0.9955 3179697 Maybridge4_002000 CNC(=O)NC(=O)CSc1ncnc2sc(cc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K21 compound treatment 0.224 -0.00219 -0.3 0.223 -0.00294 -0.42 -0.5137 -0.9862 3063391 Maybridge4_002001 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCc4ccc(Cl)cc4)n3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K22 compound treatment 0.219 -0.00719 -0.99 0.219 -0.00694 -1.0 -1.4107 -1.0 3179698 Maybridge4_002002 S=c1[nH]nc(CSc2nc(cn2c3ccccc3)c4ccccc4)n1c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K23 mock treatment 0.23 0.00381 0.53 0.23 0.00406 0.59 0.7874 0.9985 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 K24 positive control 0.228 0.00181 0.25 0.23 0.00406 0.59 0.592 0.9279 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L01 compound treatment 0.242 0.0158 2.18 0.242 0.0161 2.32 3.1853 0.9995 3063422 Maybridge4_002003 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CCCc3sc2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L02 compound treatment 0.222 -0.00419 -0.58 0.22 -0.00594 -0.86 -1.0155 -0.9816 1536081 Maybridge4_002004 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L03 compound treatment 0.275 0.0488 6.74 0.288 0.0621 8.96 11.1073 0.9902 3179699 Maybridge4_002005 C=CCn1c(nc(c1c2ccccc2)c3ccccc3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L04 compound treatment 0.219 -0.00719 -0.99 0.219 -0.00694 -1.0 -1.4107 -1.0 1430538 Maybridge4_002006 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2cccc(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L05 compound treatment 0.242 0.0158 2.18 0.239 0.0131 1.89 2.8789 0.9973 3179700 Maybridge4_002007 N=c1n(Nc2ccccc2)cnc3sc4CCCc4c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L06 compound treatment 0.224 -0.00219 -0.3 0.22 -0.00594 -0.86 -0.8201 -0.9019 3063426 Maybridge4_002008 Cc1ccc(cc1)C(=O)NC(NCc2ccco2)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L07 compound treatment 0.262 0.0358 4.95 0.255 0.0291 4.2 6.4668 0.9967 3179701 Maybridge4_002009 Brc1ccc(s1)c2ccc(Br)s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L08 compound treatment 0.273 0.0468 6.47 0.26 0.0341 4.92 8.0521 0.9909 1371799 Maybridge4_002010 CCOC(=O)C(C)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L09 compound treatment 0.224 -0.00219 -0.3 0.22 -0.00594 -0.86 -0.8201 -0.9019 1134767 Maybridge4_002011 C1C(=Cc2ccccc12)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L10 compound treatment 0.218 -0.00819 -1.13 0.218 -0.00794 -1.15 -1.6105 -1.0 1364288 Maybridge4_002012 O=C(NC1CCN(CC1)C(=O)C2CCC2)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L11 compound treatment 0.22 -0.00619 -0.85 0.22 -0.00594 -0.86 -1.2109 -1.0 1570440 Maybridge4_002013 Oc1cc(Cc2ccccc2)cnc1CN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L12 compound treatment 0.242 0.0158 2.18 0.239 0.0131 1.89 2.8789 0.9973 1227426 Maybridge4_002014 CC(C)C1CCC(C)CC1N(Cc2ccccc2)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L13 compound treatment 0.222 -0.00419 -0.58 0.224 -0.00194 -0.28 -0.607 -0.9445 1583701 Maybridge4_002015 N[C@@H](CO)CSCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L14 compound treatment 0.229 0.00281 0.39 0.223 -0.00294 -0.42 -0.0253 -0.0439 1368346 Maybridge4_002016 COc1cc(CCc2cc(OC)c(C)cc2OC)c(OC)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L15 compound treatment 0.221 -0.00519 -0.72 0.22 -0.00594 -0.86 -1.1132 -0.996 3063428 Maybridge4_002017 FC(F)(F)C(NC(=O)c1ccccc1)(Nc2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L16 compound treatment 0.265 0.0388 5.36 0.264 0.0381 5.5 7.6791 0.9999 1023708 Maybridge4_002018 COc1ccc(cc1)c2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L17 compound treatment 0.227 8.12E-4 0.11 0.228 0.00206 0.3 0.29 0.911 1344186 Maybridge4_002019 CC(=O)N1C(C(=O)NC1=S)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L18 compound treatment 0.221 -0.00519 -0.72 0.22 -0.00594 -0.86 -1.1132 -0.996 3179703 Maybridge4_002020 CC(C)C(C)(Nc1ccccc1)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L19 compound treatment 0.224 -0.00219 -0.3 0.221 -0.00494 -0.71 -0.718 -0.9269 1047316 Maybridge4_002021 OC(=O)c1ccc(s1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L20 compound treatment 0.233 0.00681 0.94 0.238 0.0121 1.74 1.8975 0.9582 3179704 Maybridge4_002022 Brc1ccccc1C(=O)c2ccc-3c(c2)C(=O)c4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L21 compound treatment 0.22 -0.00619 -0.85 0.216 -0.00994 -1.44 -1.6194 -0.9693 3063451 Maybridge4_002023 FC(F)(F)C(NC(=O)c1ccccc1)(OCc2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L22 compound treatment 0.222 -0.00419 -0.58 0.221 -0.00494 -0.71 -0.9134 -0.9946 3179705 Maybridge4_002024 CCOC(=O)CSc1nncc(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L23 mock treatment 0.229 0.00281 0.39 0.227 0.00106 0.15 0.3833 0.9174 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 L24 positive control 0.225 -0.00119 -0.16 0.225 -9.38E-4 -0.14 -0.2118 -0.9955 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M01 compound treatment 0.234 0.00781 1.08 0.235 0.00906 1.31 1.6888 0.9954 3063453 Maybridge4_002025 Cc1ccc(CNC(=O)Nc2ccccc2)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M02 compound treatment 0.243 0.0168 2.32 0.236 0.0101 1.45 2.6701 0.9745 3179706 Maybridge4_002026 CCOC(=O)c1nnn2c1nc(SCc3ccc(F)cc3)c4ccccc42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M03 compound treatment 0.232 0.00581 0.8 0.233 0.00706 1.02 1.2892 0.993 3179707 Maybridge4_002027 O=C(Nc1ccc(OCc2ccccc2)cc1)OCC3CN(Cc4ccccc4)CCO3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M04 compound treatment 0.269 0.0428 5.91 0.267 0.0411 5.93 8.3763 1.0 3063456 Maybridge4_002028 O=C(CC(C(=O)N1CCc2ccccc12)C(=O)N3CCc4ccccc34)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M05 compound treatment 0.229 0.00281 0.39 0.227 0.00106 0.15 0.3833 0.9174 3179708 Maybridge4_002029 O=C(OCC1CC(=NO1)c2ccccc2)c3cccc(n3)C(=O)OCC4CC(=NO4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M06 compound treatment 0.225 -0.00119 -0.16 0.222 -0.00394 -0.57 -0.5182 -0.8754 3063457 Maybridge4_002030 CC1=Nn2c(Cn3nnc4ccccc34)nnc2SC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M07 compound treatment 0.236 0.00981 1.36 0.233 0.00706 1.02 1.6799 0.9902 3179709 Maybridge4_002031 C/C(=N\O)/C(C)(C)Nc1ccc(cc1)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M08 compound treatment 0.267 0.0408 5.64 0.267 0.0411 5.93 8.1809 0.9997 3063458 Maybridge4_002032 O=C(Oc1cc(=O)oc2c3cccc4CCn(c(=O)c12)c43)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M09 compound treatment 0.325 0.0988 13.65 0.328 0.102 14.74 20.0773 0.9993 2096080 Maybridge4_002033 CCOC(=O)c1sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c2c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M10 compound treatment 0.247 0.0208 2.88 0.25 0.0241 3.48 4.4908 0.9956 3179710 Maybridge4_002034 CCOC(=O)N1CCc2c(C#N)c(NC(=O)CN3CCc4ccccc34)sc2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M11 compound treatment 0.256 0.0298 4.12 0.254 0.0281 4.05 5.7786 1.0 3063459 Maybridge4_002035 O=C(COc1nc(cc(c2cccs2)c1C#N)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M12 compound treatment 0.248 0.0218 3.01 0.24 0.0141 2.03 3.5671 0.9816 3063460 Maybridge4_002036 O=c1n(CN2CCOCC2)nc3sc4ccccc4n3c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M13 compound treatment 0.234 0.00781 1.08 0.232 0.00606 0.88 1.3824 0.9946 3179711 Maybridge4_002037 Nc1c(oc2nc(cc(c3cccs3)c12)c4ccco4)C(=O)c5ccc(Cl)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M14 compound treatment 0.293 0.0668 9.23 0.292 0.0661 9.54 13.2743 0.9999 3063486 Maybridge4_002038 Cc1nc2n(ncc2c(=O)n1NC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M15 compound treatment 0.218 -0.00819 -1.13 0.219 -0.00694 -1.0 -1.5084 -0.9982 3179712 Maybridge4_002039 CCOC(=O)c1nnn2c1n(CC=C)c(=O)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M16 compound treatment 0.304 0.0778 10.75 0.302 0.0761 10.99 15.3702 0.9999 3063487 Maybridge4_002040 COC(=O)C1=C(C)N=C2SC(=C(N)N2C1c3cccs3)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M17 compound treatment 0.321 0.0948 13.1 0.36 0.134 19.36 22.9549 0.9819 3179713 Maybridge4_002041 O=C/1NN=C(\C1=C\2/OC(=CS2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M18 compound treatment 0.322 0.0958 13.24 0.32 0.0941 13.59 18.9671 0.9999 3179714 Maybridge4_002042 Clc1ccc(CN2C(=O)/C(=C\c3cccs3)/N=C2c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M19 compound treatment 0.223 -0.00319 -0.44 0.223 -0.00294 -0.42 -0.6114 -0.9998 3063489 Maybridge4_002043 COc1ccc(cc1)n2ncc(NC(=O)N3CCOCC3)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M20 compound treatment 0.246 0.0198 2.74 0.252 0.0261 3.76 4.5974 0.9877 3179715 Maybridge4_002044 O=c1c(nc(nn1CN2CCOCC2)c3ccccc3)C(CN4CCOCC4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M21 compound treatment 0.301 0.0748 10.34 0.267 0.0411 5.93 11.5023 0.9652 3063490 Maybridge4_002045 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M22 compound treatment 0.224 -0.00219 -0.3 0.223 -0.00294 -0.42 -0.5137 -0.9862 3179716 Maybridge4_002046 CCOC(=O)c1cnc(nc1N)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M23 mock treatment 0.227 8.12E-4 0.11 0.226 6.25E-5 0.01 0.0858 0.7615 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 M24 positive control 0.224 -0.00219 -0.3 0.225 -9.38E-4 -0.14 -0.3094 -0.9344 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N01 compound treatment 0.228 0.00181 0.25 0.225 -9.38E-4 -0.14 0.0813 0.2856 3063492 Maybridge4_002047 O=C1CSc2nnc(c3ccccc3)n12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N02 compound treatment 0.218 -0.00819 -1.13 0.216 -0.00994 -1.44 -1.8148 -0.993 1229835 Maybridge4_002048 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N03 compound treatment 0.273 0.0468 6.47 0.27 0.0441 6.36 9.0735 1.0 1256899 Maybridge4_002049 c1csc(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N04 compound treatment 0.254 0.0278 3.84 0.259 0.0331 4.78 6.0939 0.9942 3178130 Maybridge4_002050 CCCc1cc(O)nc(SC/C=C/c2ccccc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N05 compound treatment 0.234 0.00781 1.08 0.238 0.0121 1.74 1.9952 0.9735 3178131 Maybridge4_002051 CCNc1nc(SCC(=O)NC(=O)NCc2ccccc2)nc3sc4CN(C)CCc4c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N06 compound treatment 0.25 0.0238 3.29 0.248 0.0221 3.19 4.5796 0.9999 3063494 Maybridge4_002052 CC1CN=C(S1)N(C2CCCCC2)C(=O)Nc3cccc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N07 compound treatment 0.222 -0.00419 -0.58 0.223 -0.00294 -0.42 -0.7091 -0.9884 3178132 Maybridge4_002053 Cc1ccc(OC(=O)OCSc2nnn[nH]2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N08 compound treatment 0.314 0.0878 12.13 0.314 0.0881 12.72 17.5728 0.9997 1423044 Maybridge4_002054 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N09 compound treatment 0.259 0.0328 4.53 0.258 0.0321 4.63 6.4802 0.9999 1177114 Maybridge4_002055 Brc1ccc(cc1)N2C(=O)C3=C(C2=O)C(=NCCN3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N10 compound treatment 0.219 -0.00719 -0.99 0.217 -0.00894 -1.29 -1.615 -0.9916 1659522 Maybridge4_002056 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N11 compound treatment 0.215 -0.0112 -1.55 0.213 -0.0129 -1.87 -2.4143 -0.9955 1381385 Maybridge4_002057 CN1C(=O)N(c2ccc(Cl)cc2)C(C)(O)CC1(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N12 compound treatment 0.222 -0.00419 -0.58 0.221 -0.00494 -0.71 -0.9134 -0.9946 1409714 Maybridge4_002058 COc1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N13 compound treatment 0.226 -1.88E-4 -0.03 0.223 -0.00294 -0.42 -0.3183 -0.7489 1704266 Maybridge4_002059 CC(C)(C)C(=O)Nc1ccccc1Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N14 compound treatment 0.276 0.0498 6.88 0.275 0.0491 7.09 9.8772 0.9999 3178133 Maybridge4_002060 NNC(=O)c1cc(S)ncn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N15 compound treatment 0.221 -0.00519 -0.72 0.221 -0.00494 -0.71 -1.0111 -1.0 3063524 Maybridge4_002061 CC(=O)NC(Nc1ccccc1)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N16 compound treatment 0.235 0.00881 1.22 0.233 0.00706 1.02 1.5822 0.9961 3178134 Maybridge4_002062 C/C(=N\c1ccccc1C(F)(F)F)/c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N17 compound treatment 0.221 -0.00519 -0.72 0.219 -0.00694 -1.0 -1.2153 -0.9865 1020871 Maybridge4_002063 O=C1NC(C(=O)N1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N18 compound treatment 0.226 -1.88E-4 -0.03 0.227 0.00106 0.15 0.0902 0.5796 1667495 Maybridge4_002064 Clc1ccc2[nH]c(=O)c3nc(oc3c2c1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N19 compound treatment 0.223 -0.00319 -0.44 0.223 -0.00294 -0.42 -0.6114 -0.9998 1670169 Maybridge4_002065 CC(C)c1ccc(cc1)S(=O)(=O)CC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N20 compound treatment 0.223 -0.00319 -0.44 0.222 -0.00394 -0.57 -0.7135 -0.992 1596128 Maybridge4_002066 CCOC(=O)C1CCN(C1=O)S(=O)(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N21 compound treatment 0.223 -0.00319 -0.44 0.223 -0.00294 -0.42 -0.6114 -0.9998 1008385 Maybridge4_002067 O=C(c1ccccc1)c2ccccc2C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N22 compound treatment 0.22 -0.00619 -0.85 0.219 -0.00694 -1.0 -1.313 -0.9969 1546853 Maybridge4_002068 Cn1c(=O)n(C)c2ncn(CC(O)CN(CC=C)CC=C)c2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N23 mock treatment 0.225 -0.00119 -0.16 0.224 -0.00194 -0.28 -0.3139 -0.9676 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 N24 positive control 0.223 -0.00319 -0.44 0.224 -0.00194 -0.28 -0.5093 -0.9761 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O01 compound treatment 0.311 0.0848 11.72 0.305 0.0791 11.42 16.3605 0.9999 3063527 Maybridge4_002069 O=C(Nc1sccc1c2nc3ccccc3s2)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O02 compound treatment 0.22 -0.00619 -0.85 0.218 -0.00794 -1.15 -1.4152 -0.9895 3178135 Maybridge4_002070 CCOC(=O)CSc1nnc(Cn2nnc3ccccc23)n1c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O03 compound treatment 0.215 -0.0112 -1.55 0.217 -0.00894 -1.29 -2.0057 -0.996 3063528 Maybridge4_002071 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCC2CN(Cc3ccccc3)CCO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O04 compound treatment 0.275 0.0488 6.74 0.284 0.0581 8.39 10.6988 0.9942 3178136 Maybridge4_002072 Cn1nc2c3ccccc3n(CC=C)c2nc1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O05 compound treatment 0.282 0.0558 7.71 0.268 0.0421 6.08 9.7484 0.993 3178137 Maybridge4_002073 Clc1ccc(cc1)n2ncc(n2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O06 compound treatment 0.231 0.00481 0.66 0.227 0.00106 0.15 0.5786 0.848 3178138 Maybridge4_002074 Brc1ccc(cc1)C2=Nn3c(Cn4nnc5ccccc45)nnc3SC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O07 compound treatment 0.274 0.0478 6.61 0.27 0.0441 6.36 9.1712 0.9998 1760428 Maybridge4_002075 O=C(Nc1ccc2OCCOc2c1)c3ccc4nccnc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O08 compound treatment 0.224 -0.00219 -0.3 0.222 -0.00394 -0.57 -0.6159 -0.9562 3178139 Maybridge4_002076 CNC(=O)NC(=O)CSc1nnc(o1)c2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O09 compound treatment 0.343 0.117 16.14 0.334 0.108 15.61 22.4485 0.9999 3178140 Maybridge4_002077 CCOC(=O)COc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O10 compound treatment 0.23 0.00381 0.53 0.234 0.00806 1.16 1.1959 0.9357 3063548 Maybridge4_002078 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O11 compound treatment 0.239 0.0128 1.77 0.234 0.00806 1.16 2.0751 0.9794 1200067 Maybridge4_002079 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O12 compound treatment 0.225 -0.00119 -0.16 0.221 -0.00494 -0.71 -0.6203 -0.8476 2102976 Maybridge4_002080 COc1ccc(cc1)C2=Nn3c(SC2)nc4sc5CCCCc5c4c3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O13 compound treatment 0.238 0.0118 1.63 0.237 0.0111 1.6 2.2838 0.9999 3063550 Maybridge4_002081 Cc1cc(C)c(C#N)c(Sc2ncnc3n(Cc4ccccc4)nnc23)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O14 compound treatment 0.289 0.0628 8.68 0.284 0.0581 8.39 12.0664 0.9999 3178141 Maybridge4_002082 O=c1n(/N=C/c2cccs2)cnc3sc(cc13)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O15 compound treatment 0.247 0.0208 2.88 0.244 0.0181 2.61 3.878 0.9988 3178142 Maybridge4_002083 CCOC(=O)c1nnn2c1n(Cc3ccc(Cl)cc3)c(=O)c4ccccc42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O16 compound treatment 0.257 0.0308 4.26 0.255 0.0291 4.2 5.9784 1.0 3063551 Maybridge4_002084 COc1cc(/C=N/n2c(C)nc3n(cnc3c2=O)c4ccccc4)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O17 compound treatment 0.221 -0.00519 -0.72 0.219 -0.00694 -1.0 -1.2153 -0.9865 3178143 Maybridge4_002085 O=c1nc2n(nc(c3ccccc3)n2c(c1C#N)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O18 compound treatment 0.278 0.0518 7.16 0.27 0.0441 6.36 9.5619 0.9983 3063552 Maybridge4_002086 C1Cc2ccccc2N1c3ncnc4sc(cc34)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O19 compound treatment 0.218 -0.00819 -1.13 0.219 -0.00694 -1.0 -1.5084 -0.9982 3178144 Maybridge4_002087 COc1ccc(cc1)n2ncc(NC(=O)Nc3ccc4OCCCOc4c3)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O20 compound treatment 0.233 0.00681 0.94 0.229 0.00306 0.44 0.9783 0.9407 3063553 Maybridge4_002088 Nc1ncnc2nc(ncc12)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O21 compound treatment 0.217 -0.00919 -1.27 0.215 -0.0109 -1.58 -2.0146 -0.9941 3178145 Maybridge4_002089 CC(=O)N1N=C2C(CCc3ccccc23)C1c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O22 compound treatment 0.218 -0.00819 -1.13 0.216 -0.00994 -1.44 -1.8148 -0.993 3063554 Maybridge4_002090 Cc1cc(=O)n2ncnc2n1CC(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O23 mock treatment 0.223 -0.00319 -0.44 0.222 -0.00394 -0.57 -0.7135 -0.992 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 O24 positive control 0.219 -0.00719 -0.99 0.218 -0.00794 -1.15 -1.5129 -0.9974 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P01 compound treatment 0.24 0.0138 1.91 0.228 0.00206 0.3 1.56 0.8077 1504248 Maybridge4_002091 C1Cc2ccccc2N1c3ncnc4n(ncc34)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P02 compound treatment 0.22 -0.00619 -0.85 0.22 -0.00594 -0.86 -1.2109 -1.0 1485949 Maybridge4_002092 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccc(cc3)C(C)(C)C)c4ccccn4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P03 compound treatment 0.243 0.0168 2.32 0.243 0.0171 2.46 3.3851 0.9996 3063615 Maybridge4_002093 O=C/1NNC(=N\C1=C/c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P04 compound treatment 0.225 -0.00119 -0.16 0.226 6.25E-5 0.01 -0.1096 -0.6672 3178146 Maybridge4_002094 Cn1cnnc1Sc2cc(C#N)c(C#N)cc2Sc3nncn3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P05 compound treatment 0.275 0.0488 6.74 0.273 0.0471 6.8 9.5753 1.0 3063618 Maybridge4_002095 CCNc1nc(SCc2ccc(Cl)cc2)nc3sc4CN(C)CCc4c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P06 compound treatment 0.241 0.0148 2.05 0.239 0.0131 1.89 2.7812 0.9992 3178147 Maybridge4_002096 Cn1cnc(c1C#N)n2oo2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P07 compound treatment 0.228 0.00181 0.25 0.225 -9.38E-4 -0.14 0.0813 0.2856 1405262 Maybridge4_002097 O=C(NCc1ccccc1)NC2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P08 compound treatment 0.253 0.0268 3.7 0.249 0.0231 3.33 4.9748 0.9986 1585718 Maybridge4_002098 CCOC(=O)C(C)Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P09 compound treatment 0.235 0.00881 1.22 0.233 0.00706 1.02 1.5822 0.9961 3178148 Maybridge4_002099 COC(=O)/C(=C/C(=O)c1c(F)c(F)c(OC)c(F)c1F)/O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P10 compound treatment 0.217 -0.00919 -1.27 0.218 -0.00794 -1.15 -1.7082 -0.9987 1497616 Maybridge4_002100 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)C3CCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P11 compound treatment 0.225 -0.00119 -0.16 0.227 0.00106 0.15 -0.0075 -0.0333 3178149 Maybridge4_002101 O=c1ccc2CCCCc2n1CCC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P12 compound treatment 0.222 -0.00419 -0.58 0.218 -0.00794 -1.15 -1.2198 -0.9498 1054556 Maybridge4_002102 Cc1ccc(NS(=O)(=O)c2ccccc2)c(NS(=O)(=O)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P13 compound treatment 0.22 -0.00619 -0.85 0.218 -0.00794 -1.15 -1.4152 -0.9895 1043550 Maybridge4_002103 OC1CCN(Cc2ccccc2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P14 compound treatment 0.222 -0.00419 -0.58 0.219 -0.00694 -1.0 -1.1177 -0.9659 1240290 Maybridge4_002104 CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P15 compound treatment 0.22 -0.00619 -0.85 0.22 -0.00594 -0.86 -1.2109 -1.0 3063648 Maybridge4_002105 CC(=O)NC(NCc1ccccc1)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P16 compound treatment 0.225 -0.00119 -0.16 0.222 -0.00394 -0.57 -0.5182 -0.8754 3178234 Maybridge4_002106 CC(C)[C@H]1COC(=N1)c2cccc(n2)C3=N[C@H](CO3)C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P17 compound treatment 0.217 -0.00919 -1.27 0.215 -0.0109 -1.58 -2.0146 -0.9941 3063650 Maybridge4_002107 CC(O)/C=C/c1cccc[n+]1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P18 compound treatment 0.242 0.0158 2.18 0.236 0.0101 1.45 2.5725 0.9804 3178235 Maybridge4_002108 CCOC(=O)C1=C(C)N(C(=O)Oc2ccccc2)C(=NC1c3ccccc3)SC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P19 compound treatment 0.243 0.0168 2.32 0.237 0.0111 1.6 2.7723 0.9833 3063651 Maybridge4_002109 CN1C(=O)/C(=C\Nc2ccc(Cl)cc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P20 compound treatment 0.359 0.133 18.35 0.355 0.129 18.64 26.1564 1.0 1466385 Maybridge4_002110 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OC)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P21 compound treatment 0.239 0.0128 1.77 0.248 0.0221 3.19 3.5051 0.9615 1646281 Maybridge4_002111 COc1cccc(c1)c2ncc(o2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P22 compound treatment 0.264 0.0378 5.22 0.27 0.0441 6.36 8.1943 0.9952 1592521 Maybridge4_002112 O=C(Nc1ccccc1)N(Cc2ccccc2)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P23 mock treatment 0.225 -0.00119 -0.16 0.223 -0.00294 -0.42 -0.416 -0.9145 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2054 P24 positive control 0.222 -0.00419 -0.58 0.221 -0.00494 -0.71 -0.9134 -0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A01 compound treatment 0.212 -0.0175 -2.42 0.217 -0.00806 -1.16 -2.533 -0.9439 1585984 Maybridge4_003521 CC1=NN(C(=O)C2CC2)C(=O)C1Cc3ccc(F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A02 compound treatment 0.283 0.0535 7.39 0.262 0.0369 5.34 8.999 0.9872 1074928 Maybridge4_003522 S=c1cc(ss1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A03 compound treatment 0.238 0.0085 1.17 0.227 0.00194 0.28 1.0282 0.8518 3178867 Maybridge4_003523 Fc1ccc(N(C(=O)c2ccco2)C3=NCCCC(=O)S3)c(F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A04 compound treatment 0.22 -0.0095 -1.31 0.215 -0.0101 -1.45 -1.9558 -0.9987 3065053 Maybridge4_003524 CN(C)C(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A05 compound treatment 0.25 0.0205 2.83 0.241 0.0159 2.3 3.6304 0.9947 1513145 Maybridge4_003525 CCCc1nc(SCC(=O)c2ccc(Cl)cc2)nc(OC(=O)N(CC)CC)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A06 compound treatment 0.218 -0.0115 -1.59 0.216 -0.00906 -1.31 -2.049 -0.9954 1235942 Maybridge4_003526 CC(C)(C)NC(=O)Nc1ccc2ccccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A07 compound treatment 0.277 0.0475 6.56 0.259 0.0339 4.9 8.1065 0.9897 1494176 Maybridge4_003527 Cc1cccc(NC(=S)Nc2ccccn2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A08 compound treatment 0.363 0.134 18.44 0.361 0.136 19.64 26.9257 0.9995 3065054 Maybridge4_003528 CNN1C(=O)c2cccc3cccc(C1=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A09 compound treatment 0.244 0.0145 2.0 0.25 0.0249 3.6 3.9635 0.9616 1077258 Maybridge4_003529 COc1ccc(cc1)C(CC(=O)c2ccccc2)CC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A10 compound treatment 0.221 -0.0085 -1.17 0.22 -0.00506 -0.73 -1.3474 -0.974 3065056 Maybridge4_003530 Brc1ccc(cc1)C(=O)CC(CC(=O)c2ccc(Br)cc2)c3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A11 compound treatment 0.213 -0.0165 -2.28 0.211 -0.0141 -2.03 -3.0482 -0.9983 1076053 Maybridge4_003531 CN(C)CN1C(=O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A12 compound treatment 0.221 -0.0085 -1.17 0.217 -0.00806 -1.16 -1.6538 -1.0 1711456 Maybridge4_003532 O=C1CSC(N1c2cccnc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A13 compound treatment 0.216 -0.0135 -1.87 0.213 -0.0121 -1.74 -2.5508 -0.9994 3065058 Maybridge4_003533 Cc1c(C)c(NC(=O)/C=C/C(=O)O)c(C)c(C)c1NC(=O)/C=C/C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A14 compound treatment 0.212 -0.0175 -2.42 0.213 -0.0121 -1.74 -2.9416 -0.9871 3065084 Maybridge4_003534 CCc1ccc(cc1)n2nn[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A15 compound treatment 0.215 -0.0145 -2.0 0.217 -0.00806 -1.16 -2.24 -0.9667 1012391 Maybridge4_003535 Clc1cccc(NC(=S)Nc2cccc(Cl)c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A16 compound treatment 0.211 -0.0185 -2.56 0.211 -0.0141 -2.03 -3.2435 -0.9935 3065085 Maybridge4_003536 Cc1oc2ccccc2c1CNC(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A17 compound treatment 0.25 0.0205 2.83 0.254 0.0289 4.18 4.9582 0.982 1164445 Maybridge4_003537 CCc1ccc(cc1)N2C(=O)CC(Sc3ccccc3N)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A18 compound treatment 0.256 0.0265 3.66 0.254 0.0289 4.18 5.5444 0.9978 3065086 Maybridge4_003538 C/C(=N\CCc1ccc(Cl)cc1)/c2ccccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A19 compound treatment 0.217 -0.0125 -1.73 0.216 -0.00906 -1.31 -2.1467 -0.9907 1020973 Maybridge4_003539 CC1(NC(=O)NC1=O)C2CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A20 compound treatment 0.223 -0.0065 -0.9 0.22 -0.00506 -0.73 -1.152 -0.9948 3065087 Maybridge4_003540 Cc1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A21 compound treatment 0.213 -0.0165 -2.28 0.213 -0.0121 -1.74 -2.8439 -0.9912 3065088 Maybridge4_003541 CC(=O)Nc1nnc(o1)c2c(C)onc2c3c(Cl)cccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A22 compound treatment 0.226 -0.0035 -0.48 0.234 0.00894 1.29 0.571 0.4142 3065089 Maybridge4_003542 Cc1cc(SCc2ccc(F)cc2)c(C)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A23 mock treatment 0.219 -0.0105 -1.45 0.218 -0.00706 -1.02 -1.7471 -0.9852 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 A24 positive control 0.214 -0.0155 -2.14 0.211 -0.0141 -2.03 -2.9505 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B01 compound treatment 0.235 0.0055 0.76 0.233 0.00794 1.15 1.348 0.98 1186435 Maybridge4_003543 CCc1ccc(O)c(c1)C2(O)C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B02 compound treatment 0.238 0.0085 1.17 0.231 0.00594 0.86 1.4368 0.9881 1389708 Maybridge4_003544 CCOc1ccc(NC23SCC(=O)C3CCc4ccccc42)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B03 compound treatment 0.227 -0.0025 -0.35 0.223 -0.00206 -0.3 -0.4549 -0.9973 1565816 Maybridge4_003545 CC(C)(C)c1ccc(cc1)C(=O)Oc2ccccc2CCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B04 compound treatment 0.458 0.229 31.57 0.431 0.206 29.75 43.3558 0.9996 3178868 Maybridge4_003546 CCSC(=S)c1c(C)nn(c1O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B05 compound treatment 0.245 0.0155 2.14 0.246 0.0209 3.02 3.6527 0.9857 1315983 Maybridge4_003547 Clc1ccc(NC(C#N)c2ccccc2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B06 compound treatment 0.229 -5.0E-4 -0.07 0.222 -0.00306 -0.44 -0.3616 -0.8077 1049908 Maybridge4_003548 Fc1ccc(cc1)C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B07 compound treatment 0.23 5.0E-4 0.07 0.222 -0.00306 -0.44 -0.264 -0.5895 3178869 Maybridge4_003549 NC(=S)Nc1ccccc1OC(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B08 compound treatment 0.232 0.0025 0.35 0.228 0.00294 0.42 0.5443 0.9948 3178870 Maybridge4_003550 COc1ccc(cc1)C(=O)NCc2c(C)onc2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B09 compound treatment 0.24 0.0105 1.45 0.237 0.0119 1.72 2.245 0.9963 3065091 Maybridge4_003551 CC1CN(CC(C)O1)c2ccccc2OC(=O)Nc3ccc(OC(F)(F)F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B10 compound treatment 0.263 0.0335 4.63 0.276 0.0509 7.36 8.4752 0.975 3178871 Maybridge4_003552 Clc1ccc2nc(NC(=O)C3CN(C3)C(c4ccccc4)c5ccccc5)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B11 compound treatment 0.273 0.0435 6.01 0.294 0.0689 9.96 11.2906 0.9708 3178872 Maybridge4_003553 COc1ccc2cc(ccc2c1)C(C)C(=O)Nc3ccc(OC(F)(F)F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B12 compound treatment 0.229 -5.0E-4 -0.07 0.222 -0.00306 -0.44 -0.3616 -0.8077 3065092 Maybridge4_003554 CCc1ccnc(NC(=O)CC2(CC(=O)O)CCCCC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B13 compound treatment 0.23 5.0E-4 0.07 0.229 0.00394 0.57 0.451 0.7872 1734850 Maybridge4_003555 COc1cc2N3C(=O)c4ccccc4C3(O)OC(=O)c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B14 compound treatment 0.227 -0.0025 -0.35 0.219 -0.00606 -0.88 -0.8634 -0.9172 3065093 Maybridge4_003556 Cc1nn(nc1CNC(=O)c2cc(F)cc3COCOc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B15 compound treatment 0.225 -0.0045 -0.62 0.22 -0.00506 -0.73 -0.9567 -0.9967 3178873 Maybridge4_003557 NNC(=S)NCc1ccc(F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B16 compound treatment 0.226 -0.0035 -0.48 0.223 -0.00206 -0.3 -0.5526 -0.9729 3178874 Maybridge4_003558 Cc1nn(C)c2sc(cc12)C(=O)N(Cc3ccccn3)Cc4ccccn4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B17 compound treatment 0.228 -0.0015 -0.21 0.226 9.38E-4 0.14 -0.0508 -0.2051 3065094 Maybridge4_003559 CN/1N=C(CS\C1=N\c2ccccc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B18 compound treatment 0.279 0.0495 6.84 0.276 0.0509 7.36 10.0382 0.9993 3178875 Maybridge4_003560 O=C(Nc1ccc(cc1)N2CCOCC2)c3cnc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B19 compound treatment 0.226 -0.0035 -0.48 0.222 -0.00306 -0.44 -0.6547 -0.999 1661129 Maybridge4_003561 Cc1ccc(CNC(=S)NCCO)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B20 compound treatment 0.225 -0.0045 -0.62 0.22 -0.00506 -0.73 -0.9567 -0.9967 3178876 Maybridge4_003562 CN1CCN(CC1)c2ccc(CNC(=O)c3ccc4OCCOc4c3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B21 compound treatment 0.241 0.0115 1.59 0.241 0.0159 2.3 2.7512 0.9836 1246483 Maybridge4_003563 COc1ccc(cc1)C2C3CCc4ccccc4C3=NN2CCOC(=O)C5CC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B22 compound treatment 0.224 -0.0055 -0.76 0.218 -0.00706 -1.02 -1.2586 -0.9895 1407515 Maybridge4_003564 CCOC(=O)C1CCN(CC1)C(=O)CN2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B23 mock treatment 0.233 0.0035 0.48 0.224 -0.00106 -0.15 0.2334 0.4601 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 B24 positive control 0.23 5.0E-4 0.07 0.224 -0.00106 -0.15 -0.0597 -0.3546 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C01 compound treatment 0.254 0.0245 3.38 0.252 0.0269 3.89 5.1447 0.9976 3178877 Maybridge4_003565 CCCc1cc(O)nc(NC(=N)Nc2cccc(c2)C(F)(F)F)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C02 compound treatment 0.232 0.0025 0.35 0.227 0.00194 0.28 0.4421 0.9946 3065097 Maybridge4_003566 O=C1N(Nc2ccc(cc2)N3CCOCC3)C(=O)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C03 compound treatment 0.246 0.0165 2.28 0.252 0.0269 3.89 4.3632 0.9675 3065098 Maybridge4_003567 CCCc1nc(SCC2CC2)nc(O)c1CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C04 compound treatment 0.377 0.147 20.38 0.359 0.134 19.35 28.0891 0.9997 3178878 Maybridge4_003568 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccnn2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C05 compound treatment 0.317 0.0875 12.09 0.295 0.0699 10.1 15.691 0.996 3178879 Maybridge4_003569 FC(F)(F)c1ccc(NC(=S)NC(=O)/C=C/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C06 compound treatment 0.227 -0.0025 -0.35 0.224 -0.00106 -0.15 -0.3527 -0.9333 1525321 Maybridge4_003570 CCc1ccc(NC(=S)Nc2ccccc2C(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C07 compound treatment 0.248 0.0185 2.56 0.243 0.0179 2.59 3.6393 1.0 1218939 Maybridge4_003571 NNC(=S)NC1CCCCCCCCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C08 compound treatment 0.276 0.0465 6.42 0.264 0.0389 5.62 8.5195 0.9978 3065100 Maybridge4_003572 C(N1C2CCCCCN2c3ccccc13)c4ccncc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C09 compound treatment 0.29 0.0605 8.36 0.279 0.0539 7.79 11.4192 0.9994 3178880 Maybridge4_003573 O=C(CC(CC(=O)c1ccccc1)c2cccc3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C10 compound treatment 0.301 0.0715 9.88 0.31 0.0849 12.27 15.66 0.9942 3178881 Maybridge4_003574 Cn1cccc1C(=S)NC(=O)Nc2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C11 compound treatment 0.218 -0.0115 -1.59 0.219 -0.00606 -0.88 -1.7426 -0.9606 3065101 Maybridge4_003575 CC1CC(CC(C)(C)C1)NC(=S)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C12 compound treatment 0.225 -0.0045 -0.62 0.222 -0.00306 -0.44 -0.7524 -0.9861 3065130 Maybridge4_003576 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C13 compound treatment 0.275 0.0455 6.29 0.276 0.0509 7.36 9.6475 0.9969 1084590 Maybridge4_003577 FC(F)(F)c1cccc(c1)n2c(=O)c3ccccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C14 compound treatment 0.255 0.0255 3.52 0.256 0.0309 4.47 5.6509 0.9931 3065131 Maybridge4_003578 COc1ccc(Nc2cc(ccc2Cl)C(F)(F)F)c(c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C15 compound treatment 0.221 -0.0085 -1.17 0.222 -0.00306 -0.44 -1.1431 -0.911 1657408 Maybridge4_003579 CCOc1ccc(cc1)n2c(=O)c3cc4c(=O)n(c5ccc(OCC)cc5)c(=O)c4cc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C16 compound treatment 0.276 0.0465 6.42 0.278 0.0529 7.65 9.9494 0.9962 3065132 Maybridge4_003580 C/C(=N\CCc1c[nH]c2ccccc12)/c3ccccc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C17 compound treatment 0.221 -0.0085 -1.17 0.229 0.00394 0.57 -0.4282 -0.3282 3065134 Maybridge4_003581 CCc1ccc(NC2=NCCS2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C18 compound treatment 0.225 -0.0045 -0.62 0.226 9.38E-4 0.14 -0.3438 -0.5404 3065135 Maybridge4_003582 Clc1ccc(CCn2nn[nH]c2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C19 compound treatment 0.255 0.0255 3.52 0.257 0.0319 4.61 5.7531 0.9911 1919115 Maybridge4_003583 COc1ccc(CC/N=C/c2ccccc2O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C20 compound treatment 0.473 0.243 33.64 0.465 0.24 34.66 48.2938 0.9999 3065136 Maybridge4_003584 O=C1C(=C(Nc2cccnc2)C#N)C(=O)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C21 compound treatment 0.247 0.0175 2.42 0.242 0.0169 2.45 3.4395 1.0 1317332 Maybridge4_003585 CC(C)c1cccc(C(C)C)c1NC(=S)Nc2cccc(C)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C22 compound treatment 0.341 0.112 15.4 0.342 0.117 16.89 22.836 0.9989 3065137 Maybridge4_003586 Clc1ccc(s1)C(=O)CC2OC(=O)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C23 mock treatment 0.231 0.0015 0.21 0.225 -6.25E-5 -0.01 0.1401 0.6757 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 C24 positive control 0.233 0.0035 0.48 0.226 9.38E-4 0.14 0.4377 0.8716 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D01 compound treatment 0.328 0.0985 13.61 0.339 0.114 16.46 21.2596 0.9955 1200638 Maybridge4_003587 Cc1ccc(cc1)N2C(C(=O)c3ccc(C)cc3O)c4ccccc4C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D02 compound treatment 0.223 -0.0065 -0.9 0.219 -0.00606 -0.88 -1.2542 -0.9999 1391574 Maybridge4_003588 COc1ccc(Cc2nnc(N)o2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D03 compound treatment 0.223 -0.0065 -0.9 0.22 -0.00506 -0.73 -1.152 -0.9948 1057870 Maybridge4_003589 O=C1CC(=O)N(Cc2ccccc2)C(=O)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D04 compound treatment 0.372 0.142 19.69 0.384 0.159 22.96 30.1541 0.9971 1006014 Maybridge4_003590 OC(=O)c1cc(O)nc(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D05 compound treatment 0.221 -0.0085 -1.17 0.217 -0.00806 -1.16 -1.6538 -1.0 3178961 Maybridge4_003591 Cc1ccc(F)cc1N2C(=O)COCC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D06 compound treatment 0.223 -0.0065 -0.9 0.218 -0.00706 -1.02 -1.3563 -0.998 3065138 Maybridge4_003592 N[C@@H](CC1CCCCC1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D07 compound treatment 0.226 -0.0035 -0.48 0.225 -6.25E-5 -0.01 -0.3483 -0.7202 3178962 Maybridge4_003593 OCC1(CO)CSC(=N1)Nc2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D08 compound treatment 0.224 -0.0055 -0.76 0.222 -0.00306 -0.44 -0.8501 -0.9669 3065139 Maybridge4_003594 Cc1onc(c1CNC(=O)C2CCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D09 compound treatment 0.228 -0.0015 -0.21 0.219 -0.00606 -0.88 -0.7657 -0.8509 3178963 Maybridge4_003595 FC(F)(F)Oc1ccc(NC(=O)Oc2ccccc2N3CCOCC3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D10 compound treatment 0.267 0.0375 5.18 0.264 0.0389 5.62 7.6403 0.9992 3178964 Maybridge4_003596 O=C(NCc1cc2ccccc2s1)C3CN(C3)C(c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D11 compound treatment 0.22 -0.0095 -1.31 0.22 -0.00506 -0.73 -1.4451 -0.9619 1719612 Maybridge4_003597 O=C1CC2(CCCc3ccccc32)C(=O)N1CN4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D12 compound treatment 0.282 0.0525 7.25 0.295 0.0699 10.1 12.2719 0.9868 3178965 Maybridge4_003598 Fc1cc(NC(=O)Nc2ccc(cc2)c3nc4ccccc4s3)c5OCOCc5c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D13 compound treatment 0.28 0.0505 6.98 0.27 0.0449 6.49 9.5231 0.9994 3065140 Maybridge4_003599 CCCC(/N=C/c1cc(Cl)ccc1O)/N=C/c2cc(Cl)ccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D14 compound treatment 0.239 0.0095 1.31 0.239 0.0139 2.01 2.3516 0.9785 3178966 Maybridge4_003600 CC(C)c1ccc(NC(=O)c2cc(F)cc3COCOc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D15 compound treatment 0.222 -0.0075 -1.04 0.219 -0.00606 -0.88 -1.3519 -0.9965 3065142 Maybridge4_003601 Fc1ccc(Cn2nn[nH]c2=S)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D16 compound treatment 0.222 -0.0075 -1.04 0.223 -0.00206 -0.3 -0.9433 -0.875 3178967 Maybridge4_003602 Cc1cc(CNC(=O)c2cc(C)n(C)n2)c(o1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D17 compound treatment 0.327 0.0975 13.47 0.373 0.148 21.37 24.6346 0.9752 1581411 Maybridge4_003603 COc1ccc(NC(=S)N2CCCC(=N2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D18 compound treatment 0.217 -0.0125 -1.73 0.225 -6.25E-5 -0.01 -1.2275 -0.7108 3065143 Maybridge4_003604 COc1ccc(CC(=O)Nc2ccc(cc2)N3CCOCC3)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D19 compound treatment 0.218 -0.0115 -1.59 0.219 -0.00606 -0.88 -1.7426 -0.9606 3178968 Maybridge4_003605 CN(C)C(=S)NCCC1=CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D20 compound treatment 0.224 -0.0055 -0.76 0.218 -0.00706 -1.02 -1.2586 -0.9895 3065144 Maybridge4_003606 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccc4OCCc4c3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D21 compound treatment 0.258 0.0285 3.94 0.269 0.0439 6.35 7.2718 0.9736 3178969 Maybridge4_003607 CSc1ccc(cc1)C2C3CCCc4ccccc4C3=NN2CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D22 compound treatment 0.253 0.0235 3.25 0.246 0.0209 3.02 4.4342 0.9994 1607790 Maybridge4_003608 Fc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D23 mock treatment 0.229 -5.0E-4 -0.07 0.227 0.00194 0.28 0.149 0.5171 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 D24 positive control 0.232 0.0025 0.35 0.227 0.00194 0.28 0.4421 0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E01 compound treatment 0.217 -0.0125 -1.73 0.223 -0.00206 -0.3 -1.4318 -0.817 1514931 Maybridge4_003609 CC(C)(C)C(=O)Nc1nc(NC(=O)C(C)(C)C)nc(n1)c2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E02 compound treatment 0.268 0.0385 5.32 0.266 0.0409 5.91 7.9423 0.9986 3178970 Maybridge4_003610 CC1CC(CC(C)(C)C1)NC(=S)Nc2cc(C)ccc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E03 compound treatment 0.225 -0.0045 -0.62 0.218 -0.00706 -1.02 -1.1609 -0.9718 3065145 Maybridge4_003611 Cc1cccc(C)c1NC(=S)N2CCCC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E04 compound treatment 0.27 0.0405 5.6 0.262 0.0369 5.34 7.7291 0.9997 3178971 Maybridge4_003612 Oc1ccccc1/C=N/c2ccccc2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E05 compound treatment 0.246 0.0165 2.28 0.253 0.0279 4.04 4.4653 0.9634 3178972 Maybridge4_003613 Oc1nc(S)nc(c1Cc2ccc(Cl)c(Cl)c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E06 compound treatment 0.3 0.0705 9.74 0.294 0.0689 9.96 13.9281 0.9999 3065146 Maybridge4_003614 CCOc1ccc(NC(=S)NC(c2ccccc2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E07 compound treatment 0.227 -0.0025 -0.35 0.223 -0.00206 -0.3 -0.4549 -0.9973 3178973 Maybridge4_003615 Cc1cccc(C)c1NC2=NCCS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E08 compound treatment 0.35 0.121 16.65 0.341 0.116 16.75 23.613 1.0 3065190 Maybridge4_003616 COc1cc(CN2C3CCCCCN3c4ccccc24)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E09 compound treatment 0.225 -0.0045 -0.62 0.219 -0.00606 -0.88 -1.0588 -0.9859 1023038 Maybridge4_003617 CN(C)C(=S)Nc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E10 compound treatment 0.221 -0.0085 -1.17 0.22 -0.00506 -0.73 -1.3474 -0.974 3065191 Maybridge4_003618 S=c1[nH]nnn1C2CC3CC2C4C=CCC34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E11 compound treatment 0.216 -0.0135 -1.87 0.219 -0.00606 -0.88 -1.938 -0.9406 3065192 Maybridge4_003619 C(=N/c1ccccc1)\c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E12 compound treatment 0.257 0.0275 3.8 0.253 0.0279 4.04 5.5399 0.9995 3065193 Maybridge4_003620 CC(C)(C)c1ccc(/N=C/c2ccccc2O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E13 compound treatment 0.224 -0.0055 -0.76 0.222 -0.00306 -0.44 -0.8501 -0.9669 1597004 Maybridge4_003621 CN(C)C(=S)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E14 compound treatment 0.267 0.0375 5.18 0.267 0.0419 6.06 7.9467 0.997 3065194 Maybridge4_003622 CCCNC(=O)OCN1C(=O)c2ccc(N)cc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E15 compound treatment 0.222 -0.0075 -1.04 0.216 -0.00906 -1.31 -1.6583 -0.9933 3065195 Maybridge4_003623 Cc1cccc(NC2=NCCCS2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E16 compound treatment 0.231 0.0015 0.21 0.225 -6.25E-5 -0.01 0.1401 0.6757 3178974 Maybridge4_003624 O=C1CSC(N1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E17 compound treatment 0.219 -0.0105 -1.45 0.225 -6.25E-5 -0.01 -1.0321 -0.7115 3065196 Maybridge4_003625 COc1cc(NC(=S)N(C)C)c(OC)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E18 compound treatment 0.216 -0.0135 -1.87 0.226 9.38E-4 0.14 -1.223 -0.654 1132507 Maybridge4_003626 NNC(=S)NCCc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E19 compound treatment 0.267 0.0375 5.18 0.271 0.0459 6.64 8.3553 0.9925 3178975 Maybridge4_003627 Oc1ccc2ccccc2c1/C=N/Cc3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E20 compound treatment 0.218 -0.0115 -1.59 0.219 -0.00606 -0.88 -1.7426 -0.9606 1203485 Maybridge4_003628 CC(CC(=O)O)CC(=O)Nc1ccc(C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E21 compound treatment 0.222 -0.0075 -1.04 0.219 -0.00606 -0.88 -1.3519 -0.9965 3178976 Maybridge4_003629 CSc1cccc(NC(=S)NN(C)C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E22 compound treatment 0.22 -0.0095 -1.31 0.216 -0.00906 -1.31 -1.8537 -1.0 1385701 Maybridge4_003630 CC(C)(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E23 mock treatment 0.229 -5.0E-4 -0.07 0.223 -0.00206 -0.3 -0.2595 -0.8485 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 E24 positive control 0.233 0.0035 0.48 0.227 0.00194 0.28 0.5398 0.9662 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F01 compound treatment 0.231 0.0015 0.21 0.232 0.00694 1.0 0.8551 0.8357 1225773 Maybridge4_003631 Cc1cc(C)c(O)c(c1)C2(O)C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F02 compound treatment 0.254 0.0245 3.38 0.248 0.0229 3.31 4.7361 0.9999 1310128 Maybridge4_003632 OCCn1nc(O)ccc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F03 compound treatment 0.238 0.0085 1.17 0.235 0.00994 1.44 1.8453 0.995 1400202 Maybridge4_003633 O=c1n(Cc2cccnc2)c(=S)[nH]c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F04 compound treatment 0.222 -0.0075 -1.04 0.218 -0.00706 -1.02 -1.454 -1.0 1055139 Maybridge4_003634 C(CC1CCNCC1)CC2CCNCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F05 compound treatment 0.232 0.0025 0.35 0.232 0.00694 1.0 0.9528 0.8989 1205535 Maybridge4_003635 CN1N=C2C(CCc3ccccc23)C1c4ccc(F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F06 compound treatment 0.23 5.0E-4 0.07 0.227 0.00194 0.28 0.2467 0.8559 1475761 Maybridge4_003636 OC(=O)C1CCN(CC1)C(=O)OCC2c3ccccc3-c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F07 compound treatment 0.227 -0.0025 -0.35 0.22 -0.00506 -0.73 -0.7613 -0.9414 3065197 Maybridge4_003637 COc1ccccc1NC2=NC(CO)(CO)CS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F08 compound treatment 0.225 -0.0045 -0.62 0.222 -0.00306 -0.44 -0.7524 -0.9861 3178977 Maybridge4_003638 Cc1onc(c1CNS(=O)(=O)c2cccc(Cl)c2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F09 compound treatment 0.221 -0.0085 -1.17 0.219 -0.00606 -0.88 -1.4496 -0.9896 1679129 Maybridge4_003639 OCCn1c(=O)[nH]c2ccsc2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F10 compound treatment 0.23 5.0E-4 0.07 0.225 -6.25E-5 -0.01 0.0425 0.6095 3178978 Maybridge4_003640 O=C(Nc1ccc(cc1)n2cncn2)c3ccccc3N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F11 compound treatment 0.218 -0.0115 -1.59 0.215 -0.0101 -1.45 -2.1512 -0.999 1432542 Maybridge4_003641 OC1(NC(=O)Cc2ccccc2Cl)C(=O)c3ccccc3C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F12 compound treatment 0.233 0.0035 0.48 0.238 0.0129 1.87 1.6633 0.8617 3178979 Maybridge4_003642 CSc1c(c(N)nn1C(=O)C2CCC2)c3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F13 compound treatment 0.228 -0.0015 -0.21 0.227 0.00194 0.28 0.0514 0.1475 1512720 Maybridge4_003643 CN1OC(COC(=O)c2cc(Cl)cc(Cl)c2)CC31C4CC5CC(C4)CC3C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F14 compound treatment 0.223 -0.0065 -0.9 0.227 0.00194 0.28 -0.4371 -0.4647 3065199 Maybridge4_003644 NC(=O)c1ccc(NC(=O)c2cccc3OCCCOc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F15 compound treatment 0.223 -0.0065 -0.9 0.233 0.00794 1.15 0.1758 0.1207 3065200 Maybridge4_003645 Cc1ccc2nc(oc2c1)c3ccc(cc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F16 compound treatment 0.223 -0.0065 -0.9 0.223 -0.00206 -0.3 -0.8456 -0.8938 3178980 Maybridge4_003646 Cc1cc(nn1C)C(=O)NCC2COc3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F17 compound treatment 0.385 0.156 21.48 0.341 0.116 16.75 27.0321 0.9924 3065201 Maybridge4_003647 Cc1ccc(NC(=S)N2CCCC(=N2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F18 compound treatment 0.219 -0.0105 -1.45 0.229 0.00394 0.57 -0.6236 -0.4002 3178981 Maybridge4_003648 COc1ccc(CC(=O)Nc2ccc(cc2)c3cnco3)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F19 compound treatment 0.222 -0.0075 -1.04 0.219 -0.00606 -0.88 -1.3519 -0.9965 1597585 Maybridge4_003649 COc1ccc(CNC(=S)NCCO)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F20 compound treatment 0.219 -0.0105 -1.45 0.218 -0.00706 -1.02 -1.7471 -0.9852 3065202 Maybridge4_003650 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3sc(C)nc3C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F21 compound treatment 0.25 0.0205 2.83 0.237 0.0119 1.72 3.2219 0.9717 2107603 Maybridge4_003651 O=C1/C(=C/c2ccccc2)/CCCc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F22 compound treatment 0.219 -0.0105 -1.45 0.22 -0.00506 -0.73 -1.5428 -0.9497 3179070 Maybridge4_003652 O=C1NCCCCC1NS(=O)(=O)c2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F23 mock treatment 0.23 5.0E-4 0.07 0.223 -0.00206 -0.3 -0.1618 -0.5291 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 F24 positive control 0.232 0.0025 0.35 0.226 9.38E-4 0.14 0.34 0.9164 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G01 compound treatment 0.222 -0.0075 -1.04 0.222 -0.00306 -0.44 -1.0455 -0.928 3065203 Maybridge4_003653 CC(C)(C)C(=O)Nc1nc(NC(=O)C(C)(C)C)nc(n1)c2ccccc2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G02 compound treatment 0.222 -0.0075 -1.04 0.219 -0.00606 -0.88 -1.3519 -0.9965 3179071 Maybridge4_003654 Fc1cccc(NC(=S)NCc2ccc3OCOc3c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G03 compound treatment 0.216 -0.0135 -1.87 0.215 -0.0101 -1.45 -2.3466 -0.9924 1323302 Maybridge4_003655 CCCc1nc(nc(OC(=O)N(C)C)c1Cc2c(F)cccc2Cl)c3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G04 compound treatment 0.225 -0.0045 -0.62 0.22 -0.00506 -0.73 -0.9567 -0.9967 3065204 Maybridge4_003656 COC(=C(C#N)C#N)c1c(C)onc1c2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G05 compound treatment 0.233 0.0035 0.48 0.222 -0.00306 -0.44 0.0291 0.0444 3065205 Maybridge4_003657 CC(C)(C)C(=O)Cn1nnc(n1)c2cccc(c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G06 compound treatment 0.262 0.0325 4.49 0.264 0.0389 5.62 7.1519 0.9938 3179072 Maybridge4_003658 COC(=O)c1cc(NC(=O)/C=C/C(=O)O)ccc1N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G07 compound treatment 0.265 0.0355 4.9 0.262 0.0369 5.34 7.2406 0.9991 3065206 Maybridge4_003659 Sc1nnc(Nc2ccccc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G08 compound treatment 0.228 -0.0015 -0.21 0.22 -0.00506 -0.73 -0.6636 -0.8731 3065300 Maybridge4_003660 CC1(C)NN(C(=O)N1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G09 compound treatment 0.241 0.0115 1.59 0.245 0.0199 2.88 3.1598 0.9607 1076488 Maybridge4_003661 CCOc1ccc(cc1)N2CSC(=S)N(C2)c3ccc(OCC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G10 compound treatment 0.25 0.0205 2.83 0.245 0.0199 2.88 4.039 1.0 3065240 Maybridge4_003662 CC(C)N(Cc1ccccc1)C(=S)Nc2ccc(cc2)C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G11 compound treatment 0.224 -0.0055 -0.76 0.225 -6.25E-5 -0.01 -0.5437 -0.7155 3065241 Maybridge4_003663 OCCNC(=S)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G12 compound treatment 0.255 0.0255 3.52 0.244 0.0189 2.74 4.4253 0.9922 3065242 Maybridge4_003664 CC(C)(C)C(=O)Nc1ccc(cc1)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G13 compound treatment 0.225 -0.0045 -0.62 0.223 -0.00206 -0.3 -0.6503 -0.9432 3065243 Maybridge4_003665 Cc1ccc2[nH]c(=S)n(C3CC4CC3C=C4)c(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G14 compound treatment 0.246 0.0165 2.28 0.248 0.0229 3.31 3.9546 0.9833 3065244 Maybridge4_003666 CC1(C)CC(=O)C=C(C1)NC(=O)Nc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G15 compound treatment 0.219 -0.0105 -1.45 0.218 -0.00706 -1.02 -1.7471 -0.9852 3482133 Maybridge4_003667 CC(C)C(NS(=O)(=O)c1ccccc1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G16 compound treatment 0.293 0.0635 8.77 0.28 0.0549 7.94 11.8144 0.9987 3065245 Maybridge4_003668 Cc1ccc(cc1Cl)N2C(=O)N(C(=N)C2=S)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G17 compound treatment 0.226 -0.0035 -0.48 0.224 -0.00106 -0.15 -0.4504 -0.8879 3179073 Maybridge4_003669 Cc1c(C)c(C)c(CSc2cccc(NC(=O)/C=C/C(=O)O)c2)c(C)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G18 compound treatment 0.248 0.0185 2.56 0.238 0.0129 1.87 3.1286 0.9882 3065246 Maybridge4_003670 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G19 compound treatment 0.228 -0.0015 -0.21 0.225 -6.25E-5 -0.01 -0.1529 -0.7372 3179074 Maybridge4_003671 CN(CC(=O)O)C(=S)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G20 compound treatment 0.304 0.0745 10.29 0.343 0.118 17.04 19.3237 0.9709 3179075 Maybridge4_003672 CSc1ccc(/C=N/n2c(=O)oc3ccccc3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G21 compound treatment 0.221 -0.0085 -1.17 0.218 -0.00706 -1.02 -1.5517 -0.9975 3065247 Maybridge4_003673 CN(C)NC(=S)Nc1ccc(C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G22 compound treatment 0.22 -0.0095 -1.31 0.216 -0.00906 -1.31 -1.8537 -1.0 1356260 Maybridge4_003674 N#Cc1ccc(cc1)C(N2CCSCC2)N3CCSCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G23 mock treatment 0.228 -0.0015 -0.21 0.226 9.38E-4 0.14 -0.0508 -0.2051 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 G24 positive control 0.23 5.0E-4 0.07 0.224 -0.00106 -0.15 -0.0597 -0.3546 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H01 compound treatment 0.262 0.0325 4.49 0.263 0.0379 5.48 7.0497 0.9951 3065248 Maybridge4_003675 Clc1cccc(Cl)c1CSCc2cc3ccccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H02 compound treatment 0.254 0.0245 3.38 0.257 0.0319 4.61 5.6554 0.9884 1495324 Maybridge4_003676 CSCC(O)Cn1nc(O)ccc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H03 compound treatment 0.241 0.0115 1.59 0.236 0.0109 1.58 2.2405 1.0 3065250 Maybridge4_003677 CN(C)/C=C/1\C(=O)N(C)N=C1c2ccccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H04 compound treatment 0.22 -0.0095 -1.31 0.218 -0.00706 -1.02 -1.6494 -0.9922 3179076 Maybridge4_003678 NC(=N)c1ccc(cc1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H05 compound treatment 0.265 0.0355 4.9 0.272 0.0469 6.78 8.262 0.9874 3065251 Maybridge4_003679 NC1=C(C#N)C(C#N)(C#N)C2CCCC(=C21)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H06 compound treatment 0.229 -5.0E-4 -0.07 0.22 -0.00506 -0.73 -0.5659 -0.7705 3179077 Maybridge4_003680 CC(C)(C)OC(=O)N1CCCC[C@@H]1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H07 compound treatment 0.257 0.0275 3.8 0.254 0.0289 4.18 5.642 0.9989 3179078 Maybridge4_003681 FC(F)(F)c1ccc(cc1)C(=O)NCc2csc3ccc(Cl)cc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H08 compound treatment 0.225 -0.0045 -0.62 0.224 -0.00106 -0.15 -0.5481 -0.856 3065253 Maybridge4_003682 Cc1onc(c1CNC(=O)Nc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H09 compound treatment 0.223 -0.0065 -0.9 0.217 -0.00806 -1.16 -1.4585 -0.9917 3179079 Maybridge4_003683 Fc1cccc(Cl)c1/C=N/Cc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H10 compound treatment 0.219 -0.0105 -1.45 0.22 -0.00506 -0.73 -1.5428 -0.9497 3065255 Maybridge4_003684 OC(=O)CC1(CC(=O)NCc2ccccn2)CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H11 compound treatment 0.219 -0.0105 -1.45 0.219 -0.00606 -0.88 -1.6449 -0.9708 1354093 Maybridge4_003685 CC(=O)Nc1ccccc1OCCN(Cc2ccccc2)C(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H12 compound treatment 0.253 0.0235 3.25 0.257 0.0319 4.61 5.5577 0.9852 3179080 Maybridge4_003686 CC1(C)Cc2cccc(C(=O)N3CCC(CC3)c4c[nH]c5ccccc45)c2O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H13 compound treatment 0.245 0.0155 2.14 0.247 0.0219 3.17 3.7548 0.9818 1211536 Maybridge4_003687 COc1ccc(cc1)C(=O)CC(C(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H14 compound treatment 0.261 0.0315 4.35 0.252 0.0269 3.89 5.8285 0.9984 3179081 Maybridge4_003688 FC(F)(SCc1c(Cl)cccc1Cl)C(=O)c2cnc3ccccn23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H15 compound treatment 0.224 -0.0055 -0.76 0.222 -0.00306 -0.44 -0.8501 -0.9669 3065256 Maybridge4_003689 O=C1/C(=C/C2CCCCC2)/CCCc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H16 compound treatment 0.222 -0.0075 -1.04 0.221 -0.00406 -0.59 -1.1476 -0.9637 3179082 Maybridge4_003690 Cc1cc(nn1C)C(=O)NCc2cc(F)cc3COCOc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H17 compound treatment 0.24 0.0105 1.45 0.237 0.0119 1.72 2.245 0.9963 3179083 Maybridge4_003691 CC1OCN(Cn2c1nc3ccc(Cl)cc23)c4ccc(OC(F)(F)F)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H18 compound treatment 0.222 -0.0075 -1.04 0.222 -0.00306 -0.44 -1.0455 -0.928 3065257 Maybridge4_003692 COc1ccc(CC(=O)N2CCN(CC2)c3ncccn3)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H19 compound treatment 0.225 -0.0045 -0.62 0.219 -0.00606 -0.88 -1.0588 -0.9859 3065258 Maybridge4_003693 COc1ccc(CNC(=S)NN)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H20 compound treatment 0.223 -0.0065 -0.9 0.222 -0.00306 -0.44 -0.9478 -0.9468 3179084 Maybridge4_003694 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3cccc4nonc34)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H21 compound treatment 0.233 0.0035 0.48 0.238 0.0129 1.87 1.6633 0.8617 1247395 Maybridge4_003695 CN1N=C2C(CCCc3ccccc23)C1c4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H22 compound treatment 0.22 -0.0095 -1.31 0.218 -0.00706 -1.02 -1.6494 -0.9922 3065259 Maybridge4_003696 Cc1cc(c(C)s1)S(=O)(=O)NC2CCCCNC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H23 mock treatment 0.227 -0.0025 -0.35 0.228 0.00294 0.42 0.0558 0.102 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 H24 positive control 0.232 0.0025 0.35 0.224 -0.00106 -0.15 0.1357 0.359 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I01 compound treatment 0.222 -0.0075 -1.04 0.225 -6.25E-5 -0.01 -0.739 -0.7132 1362748 Maybridge4_003697 CCc1cccc(C)c1NC(=S)NCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I02 compound treatment 0.239 0.0095 1.31 0.241 0.0159 2.3 2.5559 0.9645 3065301 Maybridge4_003698 Clc1ccc(NC(=S)NC2CCCC2)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I03 compound treatment 0.225 -0.0045 -0.62 0.221 -0.00406 -0.59 -0.8545 -0.9996 1186254 Maybridge4_003699 CCN(CC)C(=O)Oc1nc(nc(COC)c1CC2CC2)c3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I04 compound treatment 0.218 -0.0115 -1.59 0.216 -0.00906 -1.31 -2.049 -0.9954 3065303 Maybridge4_003700 C1CN=C(Nc2ccccc2c3ccccc3)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I05 compound treatment 0.268 0.0385 5.32 0.268 0.0429 6.2 8.1465 0.9971 1358941 Maybridge4_003701 Clc1ccc(cc1)c2csc(NC(=S)NC(=O)C3CC3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I06 compound treatment 0.222 -0.0075 -1.04 0.221 -0.00406 -0.59 -1.1476 -0.9637 3065304 Maybridge4_003702 CCOC(=O)c1ccc(Cl)c(NC(=S)N(C)C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I07 compound treatment 0.268 0.0385 5.32 0.263 0.0379 5.48 7.6359 0.9999 1536146 Maybridge4_003703 S=C(NCc1ccccc1)NC(Cc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I08 compound treatment 0.249 0.0195 2.69 0.237 0.0119 1.72 3.1242 0.9768 3065305 Maybridge4_003704 FC(F)(F)c1cc(NC(=S)NC2CCCCC2)cc(c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I09 compound treatment 0.256 0.0265 3.66 0.238 0.0129 1.87 3.9101 0.9513 3179085 Maybridge4_003705 S=C1SCN(Cc2ccccc2)CN1Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I10 compound treatment 0.271 0.0415 5.73 0.26 0.0349 5.05 7.6225 0.998 3179086 Maybridge4_003706 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC(=S)Nc2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I11 compound treatment 0.259 0.0295 4.08 0.258 0.0329 4.76 6.246 0.997 3065306 Maybridge4_003707 COc1ccc(CCNC(=S)NC(=O)c2ccc(Cl)cc2Cl)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I12 compound treatment 0.248 0.0185 2.56 0.25 0.0249 3.6 4.3543 0.9859 3179087 Maybridge4_003708 COc1ccc(/C=N/c2ccc(cc2)C(C)(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I13 compound treatment 0.226 -0.0035 -0.48 0.224 -0.00106 -0.15 -0.4504 -0.8879 3065307 Maybridge4_003709 Clc1cccc(Cl)c1/N=C\2/NCCS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I14 compound treatment 0.219 -0.0105 -1.45 0.218 -0.00706 -1.02 -1.7471 -0.9852 1044972 Maybridge4_003710 NNC(=O)Cc1cccc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I15 compound treatment 0.306 0.0765 10.57 0.345 0.12 17.32 19.7233 0.9719 3065308 Maybridge4_003711 Cc1ccc2[nH]c(nc2c1)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I16 compound treatment 0.221 -0.0085 -1.17 0.217 -0.00806 -1.16 -1.6538 -1.0 3179088 Maybridge4_003712 OC(=O)CC(CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccc(Cl)cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I17 compound treatment 0.223 -0.0065 -0.9 0.219 -0.00606 -0.88 -1.2542 -0.9999 3179089 Maybridge4_003713 CC(C)c1ccc2c(CCC3C(C)(CNC(=O)/C=C/C(=O)O)CCCC32C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I18 compound treatment 0.275 0.0455 6.29 0.282 0.0569 8.22 10.2603 0.9912 1216891 Maybridge4_003714 Ic1ccc(NC(=O)Cc2cccc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I19 compound treatment 0.218 -0.0115 -1.59 0.22 -0.00506 -0.73 -1.6405 -0.938 3065310 Maybridge4_003715 Fc1ccc(NC2=NCCN2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I20 compound treatment 0.22 -0.0095 -1.31 0.221 -0.00406 -0.59 -1.343 -0.9341 3179090 Maybridge4_003716 CC1CC(=O)N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I21 compound treatment 0.426 0.197 27.15 0.398 0.173 24.98 36.8592 0.9991 3065312 Maybridge4_003717 COc1ccc(/N=C/c2ccc(cc2)N(C)CCC#N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I22 compound treatment 0.22 -0.0095 -1.31 0.221 -0.00406 -0.59 -1.343 -0.9341 1341869 Maybridge4_003718 C1CN(CCO1)C(N2CCOCC2)c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I23 mock treatment 0.231 0.0015 0.21 0.226 9.38E-4 0.14 0.2423 0.9787 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 I24 positive control 0.233 0.0035 0.48 0.223 -0.00206 -0.3 0.1312 0.2311 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J01 compound treatment 0.225 -0.0045 -0.62 0.228 0.00294 0.42 -0.1396 -0.1854 1699626 Maybridge4_003719 CC(C)(C)c1ccc(NC(=O)N2CCOCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J02 compound treatment 0.293 0.0635 8.77 0.29 0.0649 9.38 12.8358 0.9994 1369792 Maybridge4_003720 Fc1ccc(cc1)C2=NN(CCC2)C(=S)NCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J03 compound treatment 0.315 0.0855 11.81 0.31 0.0849 12.27 17.0277 0.9998 3065313 Maybridge4_003721 Cc1onc(c1c2nc3ccc(I)cc3c(=O)o2)c4ccccc4Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J04 compound treatment 0.221 -0.0085 -1.17 0.221 -0.00406 -0.59 -1.2453 -0.9486 1076697 Maybridge4_003722 CC1=NN(C(=O)C1)c2cccc(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J05 compound treatment 0.213 -0.0165 -2.28 0.208 -0.0171 -2.46 -3.3546 -0.9992 3179091 Maybridge4_003723 Cn1c(=O)sn(c2ccccc2)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J06 compound treatment 0.241 0.0115 1.59 0.24 0.0149 2.16 2.6491 0.9887 3179172 Maybridge4_003724 Clc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J07 compound treatment 0.314 0.0845 11.67 0.305 0.0799 11.55 16.4193 1.0 3065315 Maybridge4_003725 Cc1ccc(cc1)C(=O)CC(C(=O)c2ccc(cc2)C(F)(F)F)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J08 compound treatment 0.225 -0.0045 -0.62 0.219 -0.00606 -0.88 -1.0588 -0.9859 3179173 Maybridge4_003726 Cc1onc(c1CNC(=O)NC2CCN(CC2)C(=O)OCc3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J09 compound treatment 0.235 0.0055 0.76 0.233 0.00794 1.15 1.348 0.98 1543567 Maybridge4_003727 CN1N=C2C(CCc3ccccc23)C1c4ccc(C#N)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J10 compound treatment 0.22 -0.0095 -1.31 0.213 -0.0121 -1.74 -2.1601 -0.9902 3065317 Maybridge4_003728 Cc1noc(c1NC(=O)Nc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J11 compound treatment 0.294 0.0645 8.91 0.292 0.0669 9.67 13.1377 0.9992 3179174 Maybridge4_003729 CCOC(=O)C1C(CC(=CC1=O)c2ccc3ccccc3c2)c4ccc(cc4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J12 compound treatment 0.252 0.0225 3.11 0.253 0.0279 4.04 5.0515 0.9917 3065318 Maybridge4_003730 CC1(C)Cc2cccc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J13 compound treatment 0.222 -0.0075 -1.04 0.22 -0.00506 -0.73 -1.2497 -0.9854 1351189 Maybridge4_003731 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J14 compound treatment 0.22 -0.0095 -1.31 0.216 -0.00906 -1.31 -1.8537 -1.0 3065319 Maybridge4_003732 CC1(C)CCc2cc(ccc2O1)S(=O)(=O)N(Cc3ccccn3)Cc4ccccn4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J15 compound treatment 0.221 -0.0085 -1.17 0.21 -0.0151 -2.18 -2.3688 -0.9581 3179175 Maybridge4_003733 COc1ccc(C/N=C/c2ccc(cc2)C(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J16 compound treatment 0.228 -0.0015 -0.21 0.217 -0.00806 -1.16 -0.97 -0.82 3065320 Maybridge4_003734 Cc1cc(nn1C)C(=O)NCc2cccn2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J17 compound treatment 0.276 0.0465 6.42 0.28 0.0549 7.94 10.1537 0.9945 3179176 Maybridge4_003735 FC(F)(F)c1ccc(/C=C(\C#N)/c2csc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J18 compound treatment 0.227 -0.0025 -0.35 0.221 -0.00406 -0.59 -0.6592 -0.9681 3065361 Maybridge4_003736 COc1ccc(CC(=O)NCc2cc(C)oc2C(F)(F)F)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J19 compound treatment 0.259 0.0295 4.08 0.252 0.0269 3.89 5.6331 0.9997 3065362 Maybridge4_003737 CCOc1cccc(/C=N/c2nnc(SC)s2)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J20 compound treatment 0.224 -0.0055 -0.76 0.224 -0.00106 -0.15 -0.6458 -0.8331 3065363 Maybridge4_003738 COC(=O)c1cc(oc1C)S(=O)(=O)N2CCSC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J21 compound treatment 0.221 -0.0085 -1.17 0.224 -0.00106 -0.15 -0.9389 -0.7928 3065364 Maybridge4_003739 Cn1c2NCN(CC3CC3)Cc2c(=O)n(C)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J22 compound treatment 0.224 -0.0055 -0.76 0.219 -0.00606 -0.88 -1.1565 -0.9975 3065366 Maybridge4_003740 O=C(NC1CCCCNC1=O)c2csc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J23 mock treatment 0.232 0.0025 0.35 0.228 0.00294 0.42 0.5443 0.9948 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 J24 positive control 0.233 0.0035 0.48 0.229 0.00394 0.57 0.7441 0.9967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K01 compound treatment 0.265 0.0355 4.9 0.264 0.0389 5.62 7.4449 0.9977 1480507 Maybridge4_003741 Clc1ccc(Oc2ccccc2NS(=O)(=O)c3ccc(NC(=O)C4CC4)cc3)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K02 compound treatment 0.233 0.0035 0.48 0.238 0.0129 1.87 1.6633 0.8617 3065367 Maybridge4_003742 CN(C)c1ccc(/C=N/N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K03 compound treatment 0.228 -0.0015 -0.21 0.223 -0.00206 -0.3 -0.3572 -0.9843 1560480 Maybridge4_003743 Cc1c(Cc2ccc(F)cc2)c(=O)oc3cc(O)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K04 compound treatment 0.223 -0.0065 -0.9 0.226 9.38E-4 0.14 -0.5392 -0.5938 3179177 Maybridge4_003744 CC(C)(C)NC(=O)Nc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K05 compound treatment 0.314 0.0845 11.67 0.307 0.0819 11.84 16.6236 1.0 1436913 Maybridge4_003745 COc1ccccc1NC(=S)NC(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K06 compound treatment 0.237 0.0075 1.04 0.242 0.0169 2.45 2.4626 0.9269 1517059 Maybridge4_003746 CCOc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K07 compound treatment 0.256 0.0265 3.66 0.256 0.0309 4.47 5.7486 0.9951 3179178 Maybridge4_003747 C1CCCCCC(CCCCC1)/N=C/c2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K08 compound treatment 0.227 -0.0025 -0.35 0.222 -0.00306 -0.44 -0.557 -0.9925 1293740 Maybridge4_003748 Cc1cc(C)cc(NC(=S)NC2CCCCC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K09 compound treatment 0.22 -0.0095 -1.31 0.214 -0.0111 -1.6 -2.0579 -0.9952 1032487 Maybridge4_003749 CCN1CSC(=S)N(CC)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K10 compound treatment 0.221 -0.0085 -1.17 0.216 -0.00906 -1.31 -1.756 -0.9985 1046043 Maybridge4_003750 NC(=N)SCCN1C(=O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K11 compound treatment 0.22 -0.0095 -1.31 0.215 -0.0101 -1.45 -1.9558 -0.9987 1157754 Maybridge4_003751 COc1ccc(CCNC(=S)N(C)C)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K12 compound treatment 0.25 0.0205 2.83 0.244 0.0189 2.74 3.9368 0.9998 3179179 Maybridge4_003752 Cc1nc2ccccc2c(=O)n1/N=C/c3ccc(Cl)c(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K13 compound treatment 0.229 -5.0E-4 -0.07 0.228 0.00294 0.42 0.2512 0.5843 1244335 Maybridge4_003753 S=C(NCc1cccnc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K14 compound treatment 0.223 -0.0065 -0.9 0.214 -0.0111 -1.6 -1.7649 -0.9629 3179180 Maybridge4_003754 O=C(NCCCN1CCOCC1)NCc2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K15 compound treatment 0.225 -0.0045 -0.62 0.217 -0.00806 -1.16 -1.2631 -0.9568 3065370 Maybridge4_003755 COc1cc(NC(=S)N)c(OC)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K16 compound treatment 0.229 -5.0E-4 -0.07 0.222 -0.00306 -0.44 -0.3616 -0.8077 3179181 Maybridge4_003756 FC(F)(F)c1cccc(NC(=O)N2CCOC32CCCCC3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K17 compound treatment 0.258 0.0285 3.94 0.253 0.0279 4.04 5.6376 0.9999 3065371 Maybridge4_003757 Cc1c(C)c(C)c(CNC(=S)NN)c(C)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K18 compound treatment 0.225 -0.0045 -0.62 0.22 -0.00506 -0.73 -0.9567 -0.9967 3179182 Maybridge4_003758 O=c1oc(nc2ccccc12)C3CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K19 compound treatment 0.228 -0.0015 -0.21 0.221 -0.00406 -0.59 -0.5615 -0.9022 3179183 Maybridge4_003759 CC/C(=N\Cc1ccc(C#N)cc1)/c2ccccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K20 compound treatment 0.223 -0.0065 -0.9 0.221 -0.00406 -0.59 -1.0499 -0.9787 1593893 Maybridge4_003760 NC(=O)C1C(C2CC1C=C2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K21 compound treatment 0.22 -0.0095 -1.31 0.217 -0.00806 -1.16 -1.7515 -0.9982 3179184 Maybridge4_003761 Fc1cccc(NC2=NCCS2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K22 compound treatment 0.261 0.0315 4.35 0.265 0.0399 5.77 7.1563 0.9903 3065373 Maybridge4_003762 Clc1ccc(cc1)C(=O)OCCc2csc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K23 mock treatment 0.232 0.0025 0.35 0.228 0.00294 0.42 0.5443 0.9948 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 K24 positive control 0.231 0.0015 0.21 0.228 0.00294 0.42 0.4466 0.9457 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L01 compound treatment 0.417 0.188 25.9 0.426 0.201 29.02 38.8399 0.9984 3179185 Maybridge4_003763 CN(C)/C=C/1\SC(=O)N(C1=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L02 compound treatment 0.282 0.0525 7.25 0.31 0.0849 12.27 13.804 0.9685 1281043 Maybridge4_003764 CC(C)c1ccc(NC(=S)N2CCCC(=N2)c3ccc(F)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L03 compound treatment 0.27 0.0405 5.6 0.276 0.0509 7.36 9.159 0.9909 3065374 Maybridge4_003765 O=C/1N(C(=N\C1=C\c2ccccc2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L04 compound treatment 0.36 0.131 18.03 0.36 0.135 19.49 26.5305 0.9992 3065375 Maybridge4_003766 OC(=O)c1cccnc1S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L05 compound treatment 0.262 0.0325 4.49 0.261 0.0359 5.19 6.8454 0.9974 3179186 Maybridge4_003767 FC(F)(F)c1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L06 compound treatment 0.25 0.0205 2.83 0.241 0.0159 2.3 3.6304 0.9947 1719441 Maybridge4_003768 Cc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L07 compound treatment 0.263 0.0335 4.63 0.253 0.0279 4.04 6.126 0.9977 3179187 Maybridge4_003769 FC(F)(F)Oc1ccc(NC(=O)OCCc2csc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L08 compound treatment 0.32 0.0905 12.5 0.303 0.0779 11.26 16.8011 0.9986 3179188 Maybridge4_003770 C1COc2cc(ccc2O1)c3nc(cs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L09 compound treatment 0.241 0.0115 1.59 0.23 0.00494 0.71 1.6277 0.9347 3065376 Maybridge4_003771 Clc1ccc(cc1)c2nnc(c3ccccc3)c(=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L10 compound treatment 0.275 0.0455 6.29 0.276 0.0509 7.36 9.6475 0.9969 3179189 Maybridge4_003772 Cc1noc(c1NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L11 compound treatment 0.273 0.0435 6.01 0.263 0.0379 5.48 8.1243 0.9989 3065377 Maybridge4_003773 CN1N=C(CC1c2ccc(F)cc2)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L12 compound treatment 0.242 0.0125 1.73 0.236 0.0109 1.58 2.3382 0.999 3179190 Maybridge4_003774 CC1(C)Cc2cccc(C(=O)Nc3cccc4CCCCc34)c2O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L13 compound treatment 0.246 0.0165 2.28 0.231 0.00594 0.86 2.2183 0.9108 3065378 Maybridge4_003775 Cc1ccc2n(CNc3ccc(OC(F)(F)F)cc3)nnc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L14 compound treatment 0.216 -0.0135 -1.87 0.212 -0.0131 -1.89 -2.653 -1.0 3179191 Maybridge4_003776 O=S(=O)(N(Cc1ccccn1)Cc2ccccn2)c3ccc(s3)c4ccon4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L15 compound treatment 0.323 0.0935 12.92 0.339 0.114 16.46 20.7712 0.9928 3065424 Maybridge4_003777 CCOC(=O)C1(CCC#N)C(CC(=CC1=O)c2ccc(OC)cc2)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L16 compound treatment 0.217 -0.0125 -1.73 0.211 -0.0141 -2.03 -2.6574 -0.9967 3065425 Maybridge4_003778 Clc1ccc(cc1)C(=O)NCc2ccc(s2)S(=O)(=O)NCCN3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L17 compound treatment 0.455 0.226 31.15 0.424 0.199 28.74 42.3477 0.9992 3065426 Maybridge4_003779 CN(C)/C=C/C(=S)c1cccs1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L18 compound treatment 0.219 -0.0105 -1.45 0.213 -0.0121 -1.74 -2.2578 -0.9959 3065427 Maybridge4_003780 CN1CCN(CC1)c2ccc(CNC(=O)c3cccnc3Oc4ccc(Cl)cc4)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L19 compound treatment 0.26 0.0305 4.21 0.257 0.0319 4.61 6.2415 0.999 3065428 Maybridge4_003781 CSc1nnc(/N=C/c2c(O)ccc3ccccc23)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L20 compound treatment 0.228 -0.0015 -0.21 0.228 0.00294 0.42 0.1535 0.3251 3065429 Maybridge4_003782 OC(CSc1nc(c2ccccc2)n(n1)c3ccccc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L21 compound treatment 0.217 -0.0125 -1.73 0.219 -0.00606 -0.88 -1.8403 -0.9505 3065430 Maybridge4_003783 Cc1ccc(Cl)cc1NC(=S)N(N)CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L22 compound treatment 0.219 -0.0105 -1.45 0.219 -0.00606 -0.88 -1.6449 -0.9708 3179192 Maybridge4_003784 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)NC3CCCCNC3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L23 mock treatment 0.232 0.0025 0.35 0.228 0.00294 0.42 0.5443 0.9948 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 L24 positive control 0.23 5.0E-4 0.07 0.225 -6.25E-5 -0.01 0.0425 0.6095 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M01 compound treatment 0.227 -0.0025 -0.35 0.226 9.38E-4 0.14 -0.1485 -0.4002 3065431 Maybridge4_003785 Clc1cccc(c1)n2c(SCC3CC3)nnc2C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M02 compound treatment 0.249 0.0195 2.69 0.249 0.0239 3.46 4.3498 0.9924 3179193 Maybridge4_003786 CN(C)C(=S)NC(Cc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M03 compound treatment 0.22 -0.0095 -1.31 0.216 -0.00906 -1.31 -1.8537 -1.0 3179194 Maybridge4_003787 CCCc1nc(SCC(=O)c2ccccc2Cl)nc(O)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M04 compound treatment 0.233 0.0035 0.48 0.226 9.38E-4 0.14 0.4377 0.8716 3065433 Maybridge4_003788 CCc1ccc(NC(=O)NC(C)(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M05 compound treatment 0.226 -0.0035 -0.48 0.219 -0.00606 -0.88 -0.9611 -0.9608 1572084 Maybridge4_003789 Cc1ccc(NC(=S)Nc2ccccc2C)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M06 compound treatment 0.227 -0.0025 -0.35 0.218 -0.00706 -1.02 -0.9656 -0.8965 1569198 Maybridge4_003790 O=C1N(Cc2ccncc2)C(=O)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M07 compound treatment 0.221 -0.0085 -1.17 0.216 -0.00906 -1.31 -1.756 -0.9985 3179195 Maybridge4_003791 C(/N=C/c1ccco1)C2CCC(C/N=C/c3ccco3)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M08 compound treatment 0.228 -0.0015 -0.21 0.225 -6.25E-5 -0.01 -0.1529 -0.7372 1300916 Maybridge4_003792 CCOc1ccc(NC(=S)NC(C)(C)CC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M09 compound treatment 0.224 -0.0055 -0.76 0.217 -0.00806 -1.16 -1.3608 -0.9786 1039987 Maybridge4_003793 CC(C)N1CSC(=S)N(C1)C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M10 compound treatment 0.29 0.0605 8.36 0.275 0.0499 7.21 11.0106 0.9973 1339416 Maybridge4_003794 Cc1cc(ccc1Br)n2c(=O)c3ccccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M11 compound treatment 0.235 0.0055 0.76 0.223 -0.00206 -0.3 0.3266 0.4002 3179196 Maybridge4_003795 COc1ccc(CCN2C(=O)/C(=C/c3ccccc3Cl)/SC2=S)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M12 compound treatment 0.224 -0.0055 -0.76 0.211 -0.0141 -2.03 -1.9736 -0.91 3065435 Maybridge4_003796 CC(C)(C)c1ccc(cc1)C2=NC(C)(C)CO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M13 compound treatment 0.229 -5.0E-4 -0.07 0.228 0.00294 0.42 0.2512 0.5843 3179281 Maybridge4_003797 S=C(NCCc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M14 compound treatment 0.23 5.0E-4 0.07 0.229 0.00394 0.57 0.451 0.7872 3179282 Maybridge4_003798 Cc1onc(c1C(=O)OC2=CC(=O)CC(C)(C)C2)c3c(Cl)cccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M15 compound treatment 0.253 0.0235 3.25 0.24 0.0149 2.16 3.8214 0.9803 3065437 Maybridge4_003799 CC(C)c1ccc(NC(=S)NCc2ccc(C#N)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M16 compound treatment 0.247 0.0175 2.42 0.244 0.0189 2.74 3.6438 0.9981 3179283 Maybridge4_003800 COc1ccc(cc1)C(=O)N/C(=N/c2c(C)cccc2C)/SC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M17 compound treatment 0.225 -0.0045 -0.62 0.217 -0.00806 -1.16 -1.2631 -0.9568 3065438 Maybridge4_003801 CSc1cccc(NC(=O)N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M18 compound treatment 0.355 0.126 17.34 0.332 0.107 15.45 23.1822 0.9983 3065439 Maybridge4_003802 N/C(=C(\N=C\c1ccc(C#N)cc1)/C#N)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M19 compound treatment 0.537 0.308 42.48 0.53 0.305 44.05 61.1848 0.9998 3179284 Maybridge4_003803 O=C1CSC(=S)N1/N=C/c2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M20 compound treatment 0.222 -0.0075 -1.04 0.222 -0.00306 -0.44 -1.0455 -0.928 3179285 Maybridge4_003804 CCC(C)(CC(=O)O)CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M21 compound treatment 0.272 0.0425 5.87 0.271 0.0459 6.64 8.8437 0.9981 3065440 Maybridge4_003805 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M22 compound treatment 0.221 -0.0085 -1.17 0.219 -0.00606 -0.88 -1.4496 -0.9896 1441619 Maybridge4_003806 COc1ccc(CCN2C(SC(C)C2=O)c3cccnc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M23 mock treatment 0.232 0.0025 0.35 0.227 0.00194 0.28 0.4421 0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 M24 positive control 0.225 -0.0045 -0.62 0.225 -6.25E-5 -0.01 -0.446 -0.7173 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N01 compound treatment 0.221 -0.0085 -1.17 0.223 -0.00206 -0.3 -1.041 -0.8593 3065441 Maybridge4_003807 S=C(N1CCSCC1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N02 compound treatment 0.258 0.0285 3.94 0.261 0.0359 5.19 6.4547 0.9907 1195820 Maybridge4_003808 CC(C)c1ccc(cc1)C2C3CCc4ccccc4C3=NN2CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N03 compound treatment 0.225 -0.0045 -0.62 0.23 0.00494 0.71 0.0647 0.0684 3065442 Maybridge4_003809 FC(F)(F)c1cc(NC(C#N)c2ccccc2)cc(c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N04 compound treatment 0.219 -0.0105 -1.45 0.216 -0.00906 -1.31 -1.9513 -0.9987 1398220 Maybridge4_003810 OC(=O)C(C(=O)OCc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N05 compound treatment 0.225 -0.0045 -0.62 0.219 -0.00606 -0.88 -1.0588 -0.9859 3065443 Maybridge4_003811 CC1CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N06 compound treatment 0.246 0.0165 2.28 0.235 0.00994 1.44 2.6268 0.9751 1541655 Maybridge4_003812 COc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N07 compound treatment 0.246 0.0165 2.28 0.251 0.0259 3.75 4.2611 0.9716 3065444 Maybridge4_003813 Oc1ccccc1/C=N/c2ccc(OC(F)(F)F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N08 compound treatment 0.27 0.0405 5.6 0.301 0.0759 10.97 11.7125 0.9512 3179286 Maybridge4_003814 CCOC(=O)c1ccc(cc1)n2c(=S)[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N09 compound treatment 0.23 5.0E-4 0.07 0.224 -0.00106 -0.15 -0.0597 -0.3546 3065445 Maybridge4_003815 CC(C)c1ccc2[n+](C)cccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N10 compound treatment 0.222 -0.0075 -1.04 0.215 -0.0101 -1.45 -1.7604 -0.9862 3064681 Maybridge4_003816 Cc1noc(c1NC(=O)N2CCOCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N11 compound treatment 0.313 0.0835 11.54 0.288 0.0629 9.09 14.5853 0.9931 1587431 Maybridge4_003817 COc1ccc(cc1)C2CC(=NN2C)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N12 compound treatment 0.225 -0.0045 -0.62 0.215 -0.0101 -1.45 -1.4674 -0.9282 3064636 Maybridge4_003818 Fc1cc(C(=O)NCc2nc3ccccc3s2)c4OCOCc4c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N13 compound treatment 0.226 -0.0035 -0.48 0.218 -0.00706 -1.02 -1.0633 -0.9418 3064637 Maybridge4_003819 OC(=O)/C=C/C(=O)Nc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N14 compound treatment 0.234 0.0045 0.62 0.231 0.00594 0.86 1.046 0.9875 3064638 Maybridge4_003820 O=C(N(Cc1ccccn1)Cc2ccccn2)c3ccc4nsnc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N15 compound treatment 0.226 -0.0035 -0.48 0.221 -0.00406 -0.59 -0.7568 -0.9954 1376553 Maybridge4_003821 CN1N=C2C(CCCc3ccccc23)C1c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N16 compound treatment 0.283 0.0535 7.39 0.275 0.0499 7.21 10.3268 0.9999 3064639 Maybridge4_003822 Cc1cc(CNC(=O)c2cnc3ccccc3n2)c(o1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N17 compound treatment 0.222 -0.0075 -1.04 0.214 -0.0111 -1.6 -1.8626 -0.978 3064640 Maybridge4_003823 COc1ccccc1CNC(=S)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N18 compound treatment 0.22 -0.0095 -1.31 0.216 -0.00906 -1.31 -1.8537 -1.0 3179287 Maybridge4_003824 CN1CCN(CC1)c2ccc(CNC(=O)c3cnn(c3C)c4ccc(Cl)cc4)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N19 compound treatment 0.265 0.0355 4.9 0.26 0.0349 5.05 7.0364 0.9999 1418353 Maybridge4_003825 CC1=NN(C(=O)C1=C2SCCCS2)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N20 compound treatment 0.306 0.0765 10.57 0.301 0.0759 10.97 15.2292 0.9998 3064641 Maybridge4_003826 OC(CSc1nccc(n1)c2ccc3OCCOc3c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N21 compound treatment 0.286 0.0565 7.81 0.269 0.0439 6.35 10.0071 0.9947 3179288 Maybridge4_003827 COc1ccc(/N=C\2/SCC(=NN2CCO)c3ccc(C)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N22 compound treatment 0.22 -0.0095 -1.31 0.218 -0.00706 -1.02 -1.6494 -0.9922 3179289 Maybridge4_003828 CC(C)(Oc1ccc(Cl)cc1)C(=O)NC2CCCCNC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N23 mock treatment 0.229 -5.0E-4 -0.07 0.224 -0.00106 -0.15 -0.1574 -0.935 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 N24 positive control 0.227 -0.0025 -0.35 0.223 -0.00206 -0.3 -0.4549 -0.9973 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O01 compound treatment 0.224 -0.0055 -0.76 0.223 -0.00206 -0.3 -0.7479 -0.9164 3064642 Maybridge4_003829 Fc1ccc(NC2=NCCCC(=O)S2)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O02 compound treatment 0.259 0.0295 4.08 0.253 0.0279 4.04 5.7353 1.0 3179290 Maybridge4_003830 Cc1cc(/N=C/c2cc(Cl)cc(Cl)c2O)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O03 compound treatment 0.217 -0.0125 -1.73 0.213 -0.0121 -1.74 -2.4531 -1.0 1155572 Maybridge4_003831 CC(C)(C)C(=O)COC(=O)Cn1nnc(n1)N2CCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O04 compound treatment 0.235 0.0055 0.76 0.226 9.38E-4 0.14 0.633 0.8202 3179291 Maybridge4_003832 CC(C)(C)NC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O05 compound treatment 0.237 0.0075 1.04 0.23 0.00494 0.71 1.237 0.9834 1006391 Maybridge4_003833 Cc1ccc(NC(=S)Nc2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O06 compound treatment 0.297 0.0675 9.33 0.285 0.0599 8.66 12.7158 0.9993 3179292 Maybridge4_003834 COc1cccc(/C=N\c2ccccc2N3C(=O)c4ccccc4C3=O)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O07 compound treatment 0.233 0.0035 0.48 0.232 0.00694 1.0 1.0505 0.9441 1631575 Maybridge4_003835 CCOc1ccc(NC(=S)NC(Cc2ccccc2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O08 compound treatment 0.271 0.0415 5.73 0.266 0.0409 5.91 8.2353 0.9999 3179293 Maybridge4_003836 CCOC(=O)c1ccc(NC(=S)NC(C)c2ccc3OCCOc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O09 compound treatment 0.293 0.0635 8.77 0.289 0.0639 9.24 12.7336 0.9997 1028763 Maybridge4_003837 OC(=O)CSC(=S)c1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O10 compound treatment 0.348 0.118 16.37 0.341 0.116 16.75 23.4177 0.9999 3179294 Maybridge4_003838 N/C(=N\O)/c1c(cc([nH]c1=O)c2ccc(F)cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O11 compound treatment 0.276 0.0465 6.42 0.269 0.0439 6.35 9.0302 1.0 1080231 Maybridge4_003839 COc1ccc(cc1)C(CC(=O)c2ccccc2)Sc3ccccc3N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O12 compound treatment 0.259 0.0295 4.08 0.239 0.0139 2.01 4.3053 0.9471 1192868 Maybridge4_003840 CC(C)c1ccc(cc1)N2C(=O)SC(C2=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O13 compound treatment 0.217 -0.0125 -1.73 0.217 -0.00806 -1.16 -2.0446 -0.9816 3179295 Maybridge4_003841 CN(C)C(=O)Nc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O14 compound treatment 0.236 0.0065 0.9 0.231 0.00594 0.86 1.2414 0.9997 3179296 Maybridge4_003842 CC(C)(C)c1ccc(cc1)C(=O)OC2=CC(=O)CC(C)(C)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O15 compound treatment 0.231 0.0015 0.21 0.221 -0.00406 -0.59 -0.2684 -0.4313 3064643 Maybridge4_003843 C/C(=N\Cc1ccc(Cl)c(Cl)c1)/c2ccccc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O16 compound treatment 0.221 -0.0085 -1.17 0.215 -0.0101 -1.45 -1.8581 -0.9944 3179297 Maybridge4_003844 CC(C)(C)NC(=S)N1CCSCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O17 compound treatment 0.238 0.0085 1.17 0.224 -0.00106 -0.15 0.7218 0.6095 3064645 Maybridge4_003845 CSc1cccc(NC(=S)Nc2cccc(SC)c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O18 compound treatment 0.274 0.0445 6.15 0.271 0.0459 6.64 9.0391 0.9993 3179298 Maybridge4_003846 CN(C)/C=C/1\N=C(NC1=O)SCc2c(Cl)cccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O19 compound treatment 0.365 0.136 18.72 0.36 0.135 19.49 27.019 0.9998 3179299 Maybridge4_003847 CCO/C=C/1\SC(=S)N(/N=C/c2cccc(Cl)c2)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O20 compound treatment 0.27 0.0405 5.6 0.264 0.0389 5.62 7.9334 1.0 3064646 Maybridge4_003848 Cc1ccc(cc1)C(=O)CC(Sc2ccccc2N)c3ccsc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O21 compound treatment 0.227 -0.0025 -0.35 0.221 -0.00406 -0.59 -0.6592 -0.9681 3179300 Maybridge4_003849 Clc1ccc(Cl)c(c1)C2=NN3C(C2)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O22 compound treatment 0.237 0.0075 1.04 0.235 0.00994 1.44 1.7477 0.9872 3064648 Maybridge4_003850 Cc1oc2ccccc2c1CCOC(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O23 mock treatment 0.229 -5.0E-4 -0.07 0.222 -0.00306 -0.44 -0.3616 -0.8077 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 O24 positive control 0.223 -0.0065 -0.9 0.219 -0.00606 -0.88 -1.2542 -0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P01 compound treatment 0.274 0.0445 6.15 0.271 0.0459 6.64 9.0391 0.9993 3179301 Maybridge4_003851 CC/1=NN(C(=O)\C1=N\O)c2cccc(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P02 compound treatment 0.243 0.0135 1.87 0.238 0.0129 1.87 2.6402 1.0 1673238 Maybridge4_003852 Fc1ccc2C3Sc4ccccc4C(=O)C3=C(c2c1)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P03 compound treatment 0.341 0.112 15.4 0.341 0.116 16.75 22.7338 0.9991 3179302 Maybridge4_003853 Cn1nc(sc1=S)c2ccccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P04 compound treatment 0.256 0.0265 3.66 0.254 0.0289 4.18 5.5444 0.9978 3179303 Maybridge4_003854 Sc1nc(c(o1)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P05 compound treatment 0.227 -0.0025 -0.35 0.218 -0.00706 -1.02 -0.9656 -0.8965 3064649 Maybridge4_003855 CC1=CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P06 compound treatment 0.274 0.0445 6.15 0.265 0.0399 5.77 8.4263 0.9995 3179304 Maybridge4_003856 FC(F)(F)C1=NCCN(C=C1)C(=O)Nc2ccc3OCCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P07 compound treatment 0.25 0.0205 2.83 0.24 0.0149 2.16 3.5283 0.991 3064650 Maybridge4_003857 FC(F)(F)Oc1ccc(Nc2n[nH]c(=S)s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P08 compound treatment 0.269 0.0395 5.46 0.274 0.0489 7.07 8.8571 0.9918 3179305 Maybridge4_003858 Clc1ccc(NC(=S)N/2CCN\C2=N/c3ccc(Cl)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P09 compound treatment 0.264 0.0345 4.77 0.233 0.00794 1.15 4.1809 0.8529 1422913 Maybridge4_003859 COc1ccc2cc(ccc2c1)C(C)C(=O)Nc3cc(Cl)cc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P10 compound treatment 0.23 5.0E-4 0.07 0.223 -0.00206 -0.3 -0.1618 -0.5291 3064682 Maybridge4_003860 OC(=O)CC1(CC(=O)Nc2cc3ccccc3cn2)CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P11 compound treatment 0.294 0.0645 8.91 0.29 0.0649 9.38 12.9335 0.9997 1218065 Maybridge4_003861 Cc1ccc(cc1)n2c(SCC(=O)C(C)(C)C)nc3ccccc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P12 compound treatment 0.252 0.0225 3.11 0.252 0.0269 3.89 4.9493 0.9938 3064683 Maybridge4_003862 Fc1cc(C(=O)NCc2csc(n2)c3cccs3)c4OCOCc4c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P13 compound treatment 0.219 -0.0105 -1.45 0.218 -0.00706 -1.02 -1.7471 -0.9852 3064684 Maybridge4_003863 Fc1ccc(CNC2=NCCS2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P14 compound treatment 0.221 -0.0085 -1.17 0.219 -0.00606 -0.88 -1.4496 -0.9896 3064685 Maybridge4_003864 O=C(N(Cc1ccccn1)Cc2ccccn2)c3ncoc3c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P15 compound treatment 0.223 -0.0065 -0.9 0.218 -0.00706 -1.02 -1.3563 -0.998 3064686 Maybridge4_003865 CC(C)(C)c1ccc(cc1)c2nc(O)nn2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P16 compound treatment 0.249 0.0195 2.69 0.241 0.0159 2.3 3.5327 0.9969 3179306 Maybridge4_003866 Fc1cc(CNC(=O)c2cnc3ccccc3n2)c4OCOCc4c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P17 compound treatment 0.222 -0.0075 -1.04 0.208 -0.0171 -2.46 -2.4754 -0.9259 3064687 Maybridge4_003867 COc1ccccc1Cn2nn[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P18 compound treatment 0.225 -0.0045 -0.62 0.221 -0.00406 -0.59 -0.8545 -0.9996 3179307 Maybridge4_003868 CN1CCN(CC1)c2ccc(CNC(=O)c3ccc4nsnc4c3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P19 compound treatment 0.244 0.0145 2.0 0.242 0.0169 2.45 3.1464 0.9951 1399162 Maybridge4_003869 OCCN1N=C2C(CCc3ccccc23)C1c4ccccc4Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P20 compound treatment 0.221 -0.0085 -1.17 0.222 -0.00306 -0.44 -1.1431 -0.911 3179308 Maybridge4_003870 Cc1csc2c(SCC(O)C(F)(F)F)ncnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P21 compound treatment 0.218 -0.0115 -1.59 0.217 -0.00806 -1.16 -1.9469 -0.9883 3064689 Maybridge4_003871 NN(CCO)C(=S)NCc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P22 compound treatment 0.219 -0.0105 -1.45 0.215 -0.0101 -1.45 -2.0535 -1.0 3179398 Maybridge4_003872 O=C(Cc1cccc2ccccc12)NC3CCCCNC3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P23 mock treatment 0.229 -5.0E-4 -0.07 0.224 -0.00106 -0.15 -0.1574 -0.935 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2059 P24 positive control 0.23 5.0E-4 0.07 0.223 -0.00206 -0.3 -0.1618 -0.5291 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A01 compound treatment 0.211 -0.0177 -2.45 0.212 -0.0188 -2.72 -3.6542 -0.9987 3179399 Maybridge4_003873 Cn1nc(cc1C(=O)NC2CCCCNC2=O)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A02 compound treatment 0.294 0.0653 9.01 0.306 0.0752 10.86 14.0549 0.9957 1395167 Maybridge4_003874 CCCC1N(CCc2sccc12)C(=S)Nc3ccc(Cl)cc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A03 compound treatment 0.217 -0.0118 -1.62 0.218 -0.0128 -1.85 -2.4552 -0.9979 3179400 Maybridge4_003875 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc4OCCCOc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A04 compound treatment 0.219 -0.00975 -1.35 0.222 -0.0088 -1.27 -1.8513 -0.9996 1342707 Maybridge4_003876 CC(C)(C)C1=NN(C(=O)C1)c2nc3ccc(Cl)cc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A05 compound treatment 0.245 0.0163 2.24 0.243 0.0122 1.76 2.8335 0.9928 3179401 Maybridge4_003877 O=C(NCc1csc(n1)c2cccs2)c3ccno3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A06 compound treatment 0.233 0.00425 0.59 0.233 0.0022 0.32 0.6399 0.9584 1644100 Maybridge4_003878 COc1ccc(OC(=O)c2cnc3SCCn3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A07 compound treatment 0.221 -0.00775 -1.07 0.221 -0.0098 -1.42 -1.758 -0.9905 3179402 Maybridge4_003879 O=C(NC1CCCCNC1=O)c2ccc(nc2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A08 compound treatment 0.362 0.133 18.41 0.357 0.126 18.23 25.9067 1.0 3179403 Maybridge4_003880 CC(C)(C)S(=O)(=O)/C(=C/c1sccc1C2OCCO2)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A09 compound treatment 0.244 0.0153 2.11 0.23 -8.0E-4 -0.12 1.408 0.6673 3064691 Maybridge4_003881 O=S(=O)(NCc1ccc(cc1)c2cccs2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A10 compound treatment 0.224 -0.00475 -0.66 0.224 -0.0068 -0.98 -1.1586 -0.9808 3179404 Maybridge4_003882 Clc1ccc(cc1)C(=O)n2cc3CSc4ccc(Cl)cc4-c3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A11 compound treatment 0.224 -0.00475 -0.66 0.223 -0.0078 -1.13 -1.2607 -0.9669 3064692 Maybridge4_003883 Cc1nn(nc1CNC(=O)CC(C)(C)C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A12 compound treatment 0.228 -7.5E-4 -0.1 0.225 -0.0058 -0.84 -0.6657 -0.7886 3179405 Maybridge4_003884 CCOC(=O)Cn1c2CCCC(=O)c2c(cc1=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A13 compound treatment 0.215 -0.0138 -1.9 0.215 -0.0158 -2.28 -2.957 -0.9958 3064694 Maybridge4_003885 Cc1noc(C)c1NC(=O)NC2CCCCNC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A14 compound treatment 0.25 0.0213 2.94 0.247 0.0162 2.34 3.7305 0.9937 3179406 Maybridge4_003886 CN(C)/C(=N/C(=S)c1ccc(Cl)cc1)/C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A15 compound treatment 0.213 -0.0158 -2.18 0.213 -0.0178 -2.57 -3.3566 -0.9966 3064695 Maybridge4_003887 Cc1cc(SCc2ncon2)c(Cl)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A16 compound treatment 0.212 -0.0168 -2.31 0.21 -0.0208 -3.0 -3.7607 -0.9917 3179407 Maybridge4_003888 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)/N=C/N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A17 compound treatment 0.209 -0.0198 -2.73 0.211 -0.0198 -2.86 -3.9517 -0.9997 3064696 Maybridge4_003889 CSc1nc(/N=C/N(C)C)n(n1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A18 compound treatment 0.257 0.0283 3.9 0.282 0.0512 7.4 7.9892 0.9554 3179408 Maybridge4_003890 Cc1c2C(=O)/C(=C/c3ccccc3)/Cn2c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A19 compound treatment 0.233 0.00425 0.59 0.234 0.0032 0.46 0.742 0.993 3179409 Maybridge4_003891 FC(F)(F)c1ccccc1NC(=S)Nc2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A20 compound treatment 0.23 0.00125 0.17 0.226 -0.0048 -0.69 -0.3682 -0.5152 3064697 Maybridge4_003892 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A21 compound treatment 0.211 -0.0177 -2.45 0.213 -0.0178 -2.57 -3.552 -0.9997 1223239 Maybridge4_003893 Clc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A22 compound treatment 0.215 -0.0138 -1.9 0.213 -0.0178 -2.57 -3.1613 -0.9889 1594618 Maybridge4_003894 Cc1oc2c(F)c(F)c(F)c(F)c2c1c3noc(n3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A23 mock treatment 0.22 -0.00875 -1.21 0.219 -0.0118 -1.7 -2.06 -0.9858 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 A24 positive control 0.214 -0.0147 -2.04 0.211 -0.0198 -2.86 -3.4632 -0.9862 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B01 compound treatment 0.355 0.126 17.44 0.356 0.125 18.08 25.1208 0.9998 3179410 Maybridge4_003895 O=C(/C=C/c1ccc(s1)c2cccs2)N3CCSCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B02 compound treatment 0.239 0.0103 1.42 0.242 0.0112 1.62 2.1452 0.9978 3064698 Maybridge4_003896 FC(F)(F)c1oc(cc1C(=O)NCc2ccco2)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B03 compound treatment 0.26 0.0313 4.32 0.271 0.0402 5.81 7.1587 0.9893 1349711 Maybridge4_003897 CSc1c([nH]c2ccccc12)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B04 compound treatment 0.233 0.00425 0.59 0.231 2.0E-4 0.03 0.4356 0.741 3179411 Maybridge4_003898 Cc1nc(sc1c2ccnn2C(=O)C(C)(C)C)c3ccc(s3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B05 compound treatment 0.264 0.0352 4.87 0.265 0.0342 4.94 6.9366 1.0 3064699 Maybridge4_003899 CCOC(=O)c1c(CS(=O)c2ccc(Cl)cc2)oc3c(F)c(F)c(F)c(F)c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B06 compound treatment 0.236 0.00725 1.0 0.245 0.0142 2.05 2.1586 0.9457 3179412 Maybridge4_003900 C/C(=N\O)/C(=O)c1ccc(cc1)c2ccccc2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B07 compound treatment 0.229 2.5E-4 0.03 0.227 -0.0038 -0.55 -0.3637 -0.6613 3179413 Maybridge4_003901 CC1(C)COC(=N1)c2sccc2C(=O)N(C3CCCCC3)C(=O)NC4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B08 compound treatment 0.233 0.00425 0.59 0.233 0.0022 0.32 0.6399 0.9584 3064701 Maybridge4_003902 Nc1ccccc1SCc2cccc(Cl)c2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B09 compound treatment 0.326 0.0973 13.44 0.321 0.0902 13.03 18.713 0.9999 1459519 Maybridge4_003903 NC(=S)c1cnc(nc1N)c2ccncc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B10 compound treatment 0.227 -0.00175 -0.24 0.236 0.0052 0.75 0.3602 0.4564 1481845 Maybridge4_003904 CCCNC(=S)N1CCC(CC1)C(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B11 compound treatment 0.27 0.0413 5.7 0.268 0.0372 5.37 7.8292 0.9996 3064731 Maybridge4_003905 NC(=S)c1ncc(cc1N2CCCC2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B12 compound treatment 0.234 0.00525 0.73 0.235 0.0042 0.61 0.9418 0.9961 3064732 Maybridge4_003906 Cc1noc(C)c1c2nc(no2)c3cccc(c3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B13 compound treatment 0.222 -0.00675 -0.93 0.226 -0.0048 -0.69 -1.1497 -0.9894 3064733 Maybridge4_003907 COc1cc(NC(=O)C(C)(C)C)ccc1Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B14 compound treatment 0.26 0.0313 4.32 0.262 0.0312 4.51 6.2395 0.9998 3064734 Maybridge4_003908 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)c4ccco4)cn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B15 compound treatment 0.22 -0.00875 -1.21 0.225 -0.0058 -0.84 -1.4472 -0.984 3064735 Maybridge4_003909 CN(N1C(=O)c2ccccc2C1=O)c3cc(ccn3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B16 compound treatment 0.223 -0.00575 -0.79 0.227 -0.0038 -0.55 -0.9498 -0.9837 1391890 Maybridge4_003910 CC(C)(C)c1cc(n(n1)c2ccc(NC(=O)COCC(=O)O)cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B17 compound treatment 0.228 -7.5E-4 -0.1 0.229 -0.0018 -0.26 -0.2571 -0.9186 3179414 Maybridge4_003911 Cc1cc(C)n(n1)c2ccc(cc2)n3cccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B18 compound treatment 0.244 0.0153 2.11 0.245 0.0142 2.05 2.9401 0.9999 1368065 Maybridge4_003912 CC(C)Cc1ccc(cc1)C(C)c2nc(no2)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B19 compound treatment 0.286 0.0573 7.91 0.274 0.0432 6.24 10.005 0.9931 1510531 Maybridge4_003913 COc1cc(cc(OC)c1OC)C(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B20 compound treatment 0.23 0.00125 0.17 0.234 0.0032 0.46 0.449 0.9099 1512133 Maybridge4_003914 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)NC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B21 compound treatment 0.229 2.5E-4 0.03 0.229 -0.0018 -0.26 -0.1594 -0.6078 3064736 Maybridge4_003915 Cc1snnc1C(=O)Oc2ccccc2c3nnco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B22 compound treatment 0.242 0.0133 1.83 0.244 0.0132 1.91 2.6426 0.9998 3179415 Maybridge4_003916 CC(C)(C)c1cc(n(n1)c2ccc(/N=C\c3ccccc3O)cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B23 mock treatment 0.234 0.00525 0.73 0.234 0.0032 0.46 0.8397 0.9763 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 B24 positive control 0.229 2.5E-4 0.03 0.229 -0.0018 -0.26 -0.1594 -0.6078 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C01 compound treatment 0.225 -0.00375 -0.52 0.224 -0.0068 -0.98 -1.0609 -0.9553 3064737 Maybridge4_003917 Clc1ccc(Oc2ncccc2C(=O)NC3CCCCNC3=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C02 compound treatment 0.283 0.0543 7.49 0.277 0.0462 6.67 10.0183 0.9983 1245123 Maybridge4_003918 O=C(NCc1ccco1)NC(=O)c2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C03 compound treatment 0.222 -0.00675 -0.93 0.224 -0.0068 -0.98 -1.3539 -0.9997 3064739 Maybridge4_003919 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3c(C)nn(C)c3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C04 compound treatment 0.294 0.0653 9.01 0.29 0.0592 8.55 12.4207 0.9997 3179416 Maybridge4_003920 CC(C)(C)c1csc(Cc2ccc(cc2)c3csnn3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C05 compound treatment 0.265 0.0362 5.01 0.264 0.0332 4.8 6.9322 0.9998 3179417 Maybridge4_003921 Cc1oc(cc1C(=O)NCc2csc(n2)c3cccs3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C06 compound treatment 0.239 0.0103 1.42 0.24 0.0092 1.33 1.941 0.9995 1605864 Maybridge4_003922 OC(=O)CCCc1nc(no1)c2cnc3SCCn3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C07 compound treatment 0.231 0.00225 0.31 0.23 -8.0E-4 -0.12 0.1381 0.4164 3179418 Maybridge4_003923 O=C(NCC1CN(Cc2ccccc2)CCO1)c3ccc(nc3)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C08 compound treatment 0.28 0.0512 7.08 0.275 0.0442 6.38 9.521 0.9987 3064740 Maybridge4_003924 COC(=O)c1cc2CSc3ccc(Cl)cc3-c2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C09 compound treatment 0.27 0.0413 5.7 0.269 0.0382 5.52 7.9313 0.9999 3179419 Maybridge4_003925 O=C(NCc1ccc(cc1)c2cccs2)C3=Cc4ccccc4OC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C10 compound treatment 0.306 0.0772 10.67 0.288 0.0572 8.26 13.3887 0.992 3064741 Maybridge4_003926 CC(C)(C)C(=O)n1cc2CSc3ccc(Cl)cc3-c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C11 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 3179420 Maybridge4_003927 COCC(=O)NCc1nn(nc1C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C12 compound treatment 0.3 0.0712 9.84 0.298 0.0672 9.71 13.8239 1.0 3064742 Maybridge4_003928 COC(=O)c1sccc1c2ccc(o2)c3ccn(n3)C(=O)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C13 compound treatment 0.228 -7.5E-4 -0.1 0.234 0.0032 0.46 0.2536 0.5353 3179421 Maybridge4_003929 Cc1cc(CNC(=O)Nc2c(C)noc2C)c(o1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C14 compound treatment 0.36 0.131 18.13 0.351 0.12 17.36 25.0985 0.9998 3064743 Maybridge4_003930 Clc1ccc(NC(=O)/C(=C\c2cccs2)/c3ccsc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C15 compound treatment 0.211 -0.0177 -2.45 0.218 -0.0128 -1.85 -3.0413 -0.9903 3179422 Maybridge4_003931 CN(C)C(=O)Oc1cccc(N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C16 compound treatment 0.228 -7.5E-4 -0.1 0.236 0.0052 0.75 0.4579 0.6038 3179423 Maybridge4_003932 FC(F)(F)Oc1ccccc1/C=N/c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C17 compound treatment 0.225 -0.00375 -0.52 0.229 -0.0018 -0.26 -0.5502 -0.9492 1299325 Maybridge4_003933 CC(C)N(C(C)C)C(=O)NC(=O)c1csnn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C18 compound treatment 0.223 -0.00575 -0.79 0.225 -0.0058 -0.84 -1.1541 -0.9996 3179518 Maybridge4_003934 FC(F)(F)C1NCCc2c1[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C19 compound treatment 0.222 -0.00675 -0.93 0.222 -0.0088 -1.27 -1.5582 -0.9884 1154654 Maybridge4_003935 Cc1noc(C)c1c2nc(CSc3ccccc3)no2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C20 compound treatment 0.324 0.0953 13.16 0.298 0.0672 9.71 16.1685 0.9888 3179519 Maybridge4_003936 O=C(NCc1ccc(s1)c2cccs2)NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C21 compound treatment 0.26 0.0313 4.32 0.262 0.0312 4.51 6.2395 0.9998 1179307 Maybridge4_003937 CC(C)NC(=O)N1CCc2sccc2C1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C22 compound treatment 0.249 0.0203 2.8 0.25 0.0192 2.77 3.9392 1.0 3064744 Maybridge4_003938 CC(C)(C)c1nc(no1)c2ccc(s2)c3ccon3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C23 mock treatment 0.234 0.00525 0.73 0.231 2.0E-4 0.03 0.5333 0.7347 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 C24 positive control 0.234 0.00525 0.73 0.233 0.0022 0.32 0.7376 0.9314 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D01 compound treatment 0.34 0.111 15.37 0.335 0.104 15.05 21.5106 0.9999 3179520 Maybridge4_003939 CC(C)(C)c1ccc(NC(=O)/C=C/c2ccc(s2)c3cccs3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D02 compound treatment 0.271 0.0423 5.84 0.266 0.0352 5.08 7.7226 0.9976 3064745 Maybridge4_003940 COc1cccc(/C=N/c2c(c(nn2C)C(F)(F)F)c3ccccc3)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D03 compound treatment 0.219 -0.00975 -1.35 0.22 -0.0108 -1.56 -2.0555 -0.9973 1138512 Maybridge4_003941 COc1ccc(cc1)S(=O)(=O)CC(C)(O)CS(=O)(=O)c2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D04 compound treatment 0.217 -0.0118 -1.62 0.219 -0.0118 -1.7 -2.3531 -0.9997 3064746 Maybridge4_003942 FC(F)(F)c1ccc(/C=N/c2cc(Cl)cc(Cl)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D05 compound treatment 0.298 0.0693 9.57 0.309 0.0782 11.3 14.7521 0.9966 3179521 Maybridge4_003943 Cc1noc(C)c1c2nc(COc3ccc(/C=C(/C#N)\S(=O)(=O)C)cc3)no2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D06 compound treatment 0.275 0.0462 6.39 0.25 0.0192 2.77 6.4791 0.9302 3064747 Maybridge4_003944 CCc1sc(nc1C(=O)OC)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D07 compound treatment 0.295 0.0663 9.15 0.3 0.0692 10.0 13.5398 0.999 3064748 Maybridge4_003945 Cc1ccsc1C(=S)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D08 compound treatment 0.24 0.0113 1.55 0.237 0.0062 0.9 1.7322 0.9657 3179522 Maybridge4_003946 FC(F)(F)c1cc(Oc2ccc(cc2)n3cccc3)cc(c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D09 compound treatment 0.265 0.0362 5.01 0.261 0.0302 4.36 6.6258 0.9976 3064749 Maybridge4_003947 CSc1ccc(s1)C(=O)NC(=O)Nc2cc(C)on2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D10 compound treatment 0.216 -0.0127 -1.76 0.217 -0.0138 -1.99 -2.655 -0.9981 3179523 Maybridge4_003948 CS/C(=N\C#N)/N1CCC(CC1)C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D11 compound treatment 0.217 -0.0118 -1.62 0.219 -0.0118 -1.7 -2.3531 -0.9997 1573241 Maybridge4_003949 Cc1noc(C)c1C(=O)Oc2ccc(cc2)c3nn[nH]c3C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D12 compound treatment 0.222 -0.00675 -0.93 0.224 -0.0068 -0.98 -1.3539 -0.9997 3064792 Maybridge4_003950 CC(C)(C)NC(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D13 compound treatment 0.254 0.0253 3.49 0.261 0.0302 4.36 5.5512 0.9939 3064793 Maybridge4_003951 CCOC(=O)c1cc(CSc2ccc(Cl)cc2)c3OCOCc3c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D14 compound treatment 0.215 -0.0138 -1.9 0.217 -0.0138 -1.99 -2.7527 -0.9997 3064794 Maybridge4_003952 COc1ccccc1N2CCN(CC2)C(=S)c3ccccc3OC(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D15 compound treatment 0.218 -0.0107 -1.49 0.219 -0.0118 -1.7 -2.2554 -0.9976 3064795 Maybridge4_003953 CN(N1C(=O)CSCC1=O)c2cc(ccn2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D16 compound treatment 0.232 0.00325 0.45 0.233 0.0022 0.32 0.5422 0.9857 3064796 Maybridge4_003954 N/C(=N\O)/c1ccc(nc1)N2CCN(CC2)c3ncccc3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D17 compound treatment 0.22 -0.00875 -1.21 0.222 -0.0088 -1.27 -1.7536 -0.9997 3064797 Maybridge4_003955 Cc1nn(c(C)c1C(=O)Oc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D18 compound treatment 0.232 0.00325 0.45 0.235 0.0042 0.61 0.7465 0.989 3064798 Maybridge4_003956 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)Oc2cccc3cccnc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D19 compound treatment 0.284 0.0553 7.63 0.277 0.0462 6.67 10.116 0.9978 3064800 Maybridge4_003957 FC(F)(F)c1ccc(cc1)C(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D20 compound treatment 0.3 0.0712 9.84 0.318 0.0872 12.6 15.8667 0.9926 3179524 Maybridge4_003958 FC(F)(F)c1cccnc1N2CCN(CC2)c3ccc(NC(=O)Nc4ccc(Cl)cc4)cn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D21 compound treatment 0.235 0.00625 0.86 0.234 0.0032 0.46 0.9374 0.9571 3064801 Maybridge4_003959 CN(C)/C=C(\C#N)/c1nnc(c2ccccn2)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D22 compound treatment 0.221 -0.00775 -1.07 0.223 -0.0078 -1.13 -1.5538 -0.9997 3179525 Maybridge4_003960 Fc1ccc(CS(=O)(=O)CCNC(=O)c2c(F)cccc2Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D23 mock treatment 0.228 -7.5E-4 -0.1 0.229 -0.0018 -0.26 -0.2571 -0.9186 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 D24 positive control 0.231 0.00225 0.31 0.233 0.0022 0.32 0.4445 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E01 compound treatment 0.211 -0.0177 -2.45 0.218 -0.0128 -1.85 -3.0413 -0.9903 3179526 Maybridge4_003961 O=C(NC1CCCCNC1=O)c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E02 compound treatment 0.228 -7.5E-4 -0.1 0.227 -0.0038 -0.55 -0.4614 -0.826 3064802 Maybridge4_003962 FC(F)(F)c1ccc(cc1)C2=NCCc3sccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E03 compound treatment 0.246 0.0173 2.38 0.246 0.0152 2.2 3.2376 0.9992 3179527 Maybridge4_003963 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc4OC(C)(C)CCc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E04 compound treatment 0.243 0.0143 1.97 0.237 0.0062 0.9 2.0253 0.9364 3064804 Maybridge4_003964 O=C(Nc1ccccc1)Nc2cccc(c2)c3nnco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E05 compound treatment 0.219 -0.00975 -1.35 0.22 -0.0108 -1.56 -2.0555 -0.9973 3064805 Maybridge4_003965 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccno2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E06 compound treatment 0.263 0.0343 4.73 0.263 0.0322 4.65 6.6347 1.0 1736114 Maybridge4_003966 COc1ccc(cc1)C2N(CCc3sccc23)C(=S)NCC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E07 compound treatment 0.227 -0.00175 -0.24 0.231 2.0E-4 0.03 -0.1505 -0.6182 3179528 Maybridge4_003967 Cc1nn(C)c(C)c1CNC(=O)c2ccc(nc2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E08 compound treatment 0.224 -0.00475 -0.66 0.227 -0.0038 -0.55 -0.8521 -0.9961 3064806 Maybridge4_003968 O=C(NC(=O)c1nnc(o1)c2ccccc2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E09 compound treatment 0.26 0.0313 4.32 0.263 0.0322 4.65 6.3416 0.9993 3179529 Maybridge4_003969 COc1ccc(cc1)n2ncc(C(=O)NCc3ccc(cc3)c4cccs4)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E10 compound treatment 0.24 0.0113 1.55 0.233 0.0022 0.32 1.3237 0.8344 3064807 Maybridge4_003970 CC(C)c1ncc2CSc3ccc(Cl)cc3-c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E11 compound treatment 0.306 0.0772 10.67 0.276 0.0452 6.53 12.163 0.9722 3179530 Maybridge4_003971 COc1ccc(cc1)c2ocnc2C(=O)NCc3nn(nc3C)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E12 compound treatment 0.265 0.0362 5.01 0.265 0.0342 4.94 7.0343 1.0 3064809 Maybridge4_003972 COC(=O)c1sccc1c2ccc(o2)c3ccn(n3)S(=O)(=O)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E13 compound treatment 0.272 0.0432 5.98 0.303 0.0722 10.43 11.5994 0.9651 3179531 Maybridge4_003973 Cc1c(C)c(C)c2[nH]c(nc2c1C)c3ccc4OCOc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E14 compound treatment 0.337 0.108 14.95 0.318 0.0872 12.6 19.4812 0.9964 3179532 Maybridge4_003974 FC(F)(F)c1cccc(NC(=O)/C(=C\c2cccs2)/c3ccsc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E15 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 3064810 Maybridge4_003975 FC(F)(F)c1ccccc1N/C(=N/C#N)/N2CCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E16 compound treatment 0.224 -0.00475 -0.66 0.225 -0.0058 -0.84 -1.0564 -0.9927 3179533 Maybridge4_003976 FC(F)(F)c1cccc(NC(=O)CS(=O)(=O)Nc2cccc(c2)C(F)(F)F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E17 compound treatment 0.238 0.00925 1.28 0.246 0.0152 2.2 2.4561 0.9668 3064811 Maybridge4_003977 Cc1cc(NC(=O)NC(=O)c2csnn2)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E18 compound treatment 0.266 0.0372 5.15 0.269 0.0382 5.52 7.5406 0.9994 3179534 Maybridge4_003978 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E19 compound treatment 0.224 -0.00475 -0.66 0.227 -0.0038 -0.55 -0.8521 -0.9961 3064812 Maybridge4_003979 Cc1noc(C)c1c2nc(CS(=O)(=O)Cc3ccc(Cl)cc3)no2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E20 compound treatment 0.215 -0.0138 -1.9 0.22 -0.0108 -1.56 -2.4463 -0.9952 3064813 Maybridge4_003980 Cc1cc(cc(C)c1I)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E21 compound treatment 0.256 0.0273 3.76 0.267 0.0362 5.23 6.3594 0.987 1590769 Maybridge4_003981 CNC(=S)N1CCc2sccc2C1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E22 compound treatment 0.552 0.323 44.66 0.554 0.323 46.68 64.5887 0.9998 3064814 Maybridge4_003982 CN(C)/C=N/C(=O)c1ccc(s1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E23 mock treatment 0.224 -0.00475 -0.66 0.23 -8.0E-4 -0.12 -0.5457 -0.819 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 E24 positive control 0.233 0.00425 0.59 0.233 0.0022 0.32 0.6399 0.9584 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F01 compound treatment 0.326 0.0973 13.44 0.308 0.0772 11.15 17.3852 0.9957 3179535 Maybridge4_003983 Clc1ccc(OC(=O)/C=C/c2ccc(s2)c3cccs3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F02 compound treatment 0.252 0.0233 3.21 0.246 0.0152 2.2 3.8237 0.9828 3064815 Maybridge4_003984 Cc1ccc(C)n1c2ccc(cc2)n3cccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F03 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 1608279 Maybridge4_003985 CC(O)(CNCc1ccc(Cl)cc1)CSc2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F04 compound treatment 0.223 -0.00575 -0.79 0.229 -0.0018 -0.26 -0.7456 -0.892 3179536 Maybridge4_003986 COC(=O)c1cc(=O)c2cc(NC(=O)c3ccc(OC(F)(F)F)cc3)ccc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F05 compound treatment 0.219 -0.00975 -1.35 0.222 -0.0088 -1.27 -1.8513 -0.9996 3064655 Maybridge4_003987 CC1(C)COC(=N1)c2sccc2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F06 compound treatment 0.224 -0.00475 -0.66 0.226 -0.0048 -0.69 -0.9543 -0.9996 1318553 Maybridge4_003988 NNC(=O)c1ccc(cc1)c2ccccc2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F07 compound treatment 0.221 -0.00775 -1.07 0.225 -0.0058 -0.84 -1.3495 -0.9926 3179537 Maybridge4_003989 OC1CS(=O)(=O)CC1S(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F08 compound treatment 0.227 -0.00175 -0.24 0.235 0.0042 0.61 0.258 0.3951 3064656 Maybridge4_003990 COc1cc(cc(c1C(=O)NCc2cccs2)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F09 compound treatment 0.266 0.0372 5.15 0.275 0.0442 6.38 8.1534 0.9943 3179538 Maybridge4_003991 CSc1ccc(s1)C(=O)NC(=O)NCc2cccc(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F10 compound treatment 0.419 0.19 26.28 0.424 0.193 27.91 38.3182 0.9996 1598180 Maybridge4_003992 CN(C)c1cnn(c2cnc3ccccc3n2)c(=O)c1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F11 compound treatment 0.215 -0.0138 -1.9 0.218 -0.0128 -1.85 -2.6506 -0.9999 3179539 Maybridge4_003993 Cc1nnsc1C(=O)Oc2ccc(cc2)c3nn[nH]c3C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F12 compound treatment 0.247 0.0182 2.52 0.246 0.0152 2.2 3.3353 0.9976 3179540 Maybridge4_003994 CC(C)(C)c1cc(n(n1)c2ccc(cc2)n3cccc3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F13 compound treatment 0.25 0.0213 2.94 0.267 0.0362 5.23 5.7733 0.9627 3064661 Maybridge4_003995 CCOC(=O)c1cc(CSc2ccc(cn2)C(F)(F)F)c3OCOCc3c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F14 compound treatment 0.215 -0.0138 -1.9 0.217 -0.0138 -1.99 -2.7527 -0.9997 1225795 Maybridge4_003996 CNC(=S)N1CCN(CC1)c2ccccc2OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F15 compound treatment 0.219 -0.00975 -1.35 0.22 -0.0108 -1.56 -2.0555 -0.9973 3179541 Maybridge4_003997 Clc1cc(Cl)cc(c1)C(=O)OCCSc2cnc3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F16 compound treatment 0.248 0.0193 2.66 0.249 0.0182 2.63 3.7394 1.0 3064703 Maybridge4_003998 CS(=O)(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F17 compound treatment 0.223 -0.00575 -0.79 0.223 -0.0078 -1.13 -1.3584 -0.9854 3179628 Maybridge4_003999 FC(F)(F)c1cccc(NC(=S)N2CCCC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F18 compound treatment 0.223 -0.00575 -0.79 0.224 -0.0068 -0.98 -1.2562 -0.9945 1219010 Maybridge4_004000 COc1cccc(Oc2ccc(OC)cc2C(=O)NN)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F19 compound treatment 0.223 -0.00575 -0.79 0.224 -0.0068 -0.98 -1.2562 -0.9945 1054347 Maybridge4_004001 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F20 compound treatment 0.225 -0.00375 -0.52 0.224 -0.0068 -0.98 -1.0609 -0.9553 1252794 Maybridge4_004002 CC(C)Cc1ccc(cc1)C(C)c2nc(no2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F21 compound treatment 0.233 0.00425 0.59 0.233 0.0022 0.32 0.6399 0.9584 3179629 Maybridge4_004003 Cc1nc(sc1C(=O)Nc2ccc(Cl)cc2)C(=O)Nc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F22 compound treatment 0.236 0.00725 1.0 0.24 0.0092 1.33 1.6479 0.9903 3179630 Maybridge4_004004 CC(C)(C)c1n[nH]c(c1Cc2c(F)cccc2Cl)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F23 mock treatment 0.23 0.00125 0.17 0.23 -8.0E-4 -0.12 0.0404 0.1944 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 F24 positive control 0.231 0.00225 0.31 0.234 0.0032 0.46 0.5466 0.9814 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G01 compound treatment 0.231 0.00225 0.31 0.233 0.0022 0.32 0.4445 0.9999 3064707 Maybridge4_004005 O=C(NC1CCCCNC1=O)c2ccc3nsnc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G02 compound treatment 0.238 0.00925 1.28 0.25 0.0192 2.77 2.8647 0.9381 3179631 Maybridge4_004006 Cc1noc(C)c1C(=O)N2CCc3sccc3C2c4ccc(cc4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G03 compound treatment 0.217 -0.0118 -1.62 0.218 -0.0128 -1.85 -2.4552 -0.9979 1266306 Maybridge4_004007 NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G04 compound treatment 0.22 -0.00875 -1.21 0.222 -0.0088 -1.27 -1.7536 -0.9997 3179632 Maybridge4_004008 CCOC(=O)c1ncoc1c2ccc(Cl)cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G05 compound treatment 0.241 0.0123 1.69 0.248 0.0172 2.48 2.9535 0.9825 3064708 Maybridge4_004009 Clc1cccc(NC(=O)NCc2csc(n2)c3cccs3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G06 compound treatment 0.291 0.0623 8.6 0.291 0.0602 8.7 12.2298 1.0 1361028 Maybridge4_004010 COc1ccc(cc1)C2N(CCc3sccc23)S(=O)(=O)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G07 compound treatment 0.219 -0.00975 -1.35 0.222 -0.0088 -1.27 -1.8513 -0.9996 3179633 Maybridge4_004011 O=C(N1CCC2(CC1)NC(=O)c3ccccc3O2)c4ncoc4c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G08 compound treatment 0.239 0.0103 1.42 0.243 0.0122 1.76 2.2474 0.9941 3064709 Maybridge4_004012 NC(=S)c1sccc1CS(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G09 compound treatment 0.241 0.0123 1.69 0.246 0.0152 2.2 2.7492 0.9917 3179634 Maybridge4_004013 COc1ccccc1CC(=O)NCc2ccc(cc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G10 compound treatment 0.227 -0.00175 -0.24 0.229 -0.0018 -0.26 -0.3548 -0.9993 3064710 Maybridge4_004014 FC(F)(F)c1cc(=O)[nH]c2CCCC(=O)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G11 compound treatment 0.235 0.00625 0.86 0.238 0.0072 1.04 1.3459 0.9957 3179635 Maybridge4_004015 Cc1nn(nc1CNC(=O)C2CC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G12 compound treatment 0.235 0.00625 0.86 0.228 -0.0028 -0.4 0.3246 0.3404 3064711 Maybridge4_004016 FC(F)(F)c1cccc(OCc2ccc(cc2)c3ncns3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G13 compound treatment 0.22 -0.00875 -1.21 0.224 -0.0068 -0.98 -1.5493 -0.9947 3179636 Maybridge4_004017 Fc1cc(C(=O)NCc2ccco2)c3OCOCc3c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G14 compound treatment 0.265 0.0362 5.01 0.24 0.0092 1.33 4.4809 0.8648 3064712 Maybridge4_004018 Fc1ccc(OC(=O)/C(=C\c2cccs2)/c3ccsc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G15 compound treatment 0.22 -0.00875 -1.21 0.222 -0.0088 -1.27 -1.7536 -0.9997 3179637 Maybridge4_004019 COC(=O)C1=NN(C(=O)C1)c2c(C)cccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G16 compound treatment 0.223 -0.00575 -0.79 0.222 -0.0088 -1.27 -1.4605 -0.9744 1285053 Maybridge4_004020 Fc1ccc(NC(=O)CS(=O)(=O)Nc2ccc(F)cc2Cl)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G17 compound treatment 0.248 0.0193 2.66 0.238 0.0072 1.04 2.6159 0.9161 3179638 Maybridge4_004021 Clc1ccc(CSCc2ccc(cc2)c3csnn3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G18 compound treatment 0.224 -0.00475 -0.66 0.224 -0.0068 -0.98 -1.1586 -0.9808 1173952 Maybridge4_004022 COc1cc(NS(=O)(=O)c2c(C)oc3c(F)c(F)c(F)c(F)c23)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G19 compound treatment 0.264 0.0352 4.87 0.264 0.0332 4.8 6.8345 1.0 1587917 Maybridge4_004023 Clc1cc(Cl)cc(c1)C(=O)NCc2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G20 compound treatment 0.238 0.00925 1.28 0.244 0.0132 1.91 2.2518 0.9811 3179639 Maybridge4_004024 Clc1ccc(/C=N/Cc2ccc(s2)c3cccs3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G21 compound treatment 0.219 -0.00975 -1.35 0.223 -0.0078 -1.13 -1.7491 -0.9961 3064752 Maybridge4_004025 Cc1cc(C(=O)O)c(C)n1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G22 compound treatment 0.324 0.0953 13.16 0.316 0.0852 12.31 18.0069 0.9994 1446641 Maybridge4_004026 COc1ccc2ncc3COc4ccc(Cl)cc4-c3c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G23 mock treatment 0.227 -0.00175 -0.24 0.231 2.0E-4 0.03 -0.1505 -0.6182 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 G24 positive control 0.23 0.00125 0.17 0.232 0.0012 0.17 0.2447 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H01 compound treatment 0.222 -0.00675 -0.93 0.223 -0.0078 -1.13 -1.4561 -0.9956 3064753 Maybridge4_004027 CC(=O)Nc1ccccc1OCC(O)CS(=O)(=O)c2ccc(cn2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H02 compound treatment 0.275 0.0462 6.39 0.269 0.0382 5.52 8.4197 0.9973 3064754 Maybridge4_004028 CC(C)c1ccc(C)c2c(C#N)cc(C)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H03 compound treatment 0.232 0.00325 0.45 0.238 0.0072 1.04 1.0529 0.9295 3064755 Maybridge4_004029 Cc1noc(c1c2nnc(o2)c3cccc(c3)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H04 compound treatment 0.227 -0.00175 -0.24 0.228 -0.0028 -0.4 -0.4569 -0.9697 3064756 Maybridge4_004030 COc1ccc(C/N=C/c2ccc(OC)c(OC)c2)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H05 compound treatment 0.221 -0.00775 -1.07 0.22 -0.0108 -1.56 -1.8602 -0.9831 3064758 Maybridge4_004031 Clc1ccc(cc1)c2cc[nH]n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H06 compound treatment 0.225 -0.00375 -0.52 0.227 -0.0038 -0.55 -0.7545 -0.9996 3179640 Maybridge4_004032 COC(=O)Cc1nc(sc1C)c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H07 compound treatment 0.217 -0.0118 -1.62 0.22 -0.0108 -1.56 -2.2509 -0.9998 1266051 Maybridge4_004033 COc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)CC2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H08 compound treatment 0.252 0.0233 3.21 0.252 0.0212 3.06 4.4366 0.9997 3179641 Maybridge4_004034 COc1cc(cc(c1C(=O)N2CCC(CC2)C(=O)c3ccc(Cl)cc3)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H09 compound treatment 0.228 -7.5E-4 -0.1 0.228 -0.0028 -0.4 -0.3593 -0.8605 1103147 Maybridge4_004035 N#Cc1c(nc2SCCn12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H10 compound treatment 0.215 -0.0138 -1.9 0.218 -0.0128 -1.85 -2.6506 -0.9999 3179642 Maybridge4_004036 Brc1cc(Br)cc(c1)C(=O)NC(=O)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H11 compound treatment 0.339 0.11 15.23 0.312 0.0812 11.73 19.0637 0.9917 3064759 Maybridge4_004037 O=S(=O)(/C(=C/c1ccc(s1)C2=CCOc3ccccc23)/C#N)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H12 compound treatment 0.314 0.0853 11.78 0.312 0.0812 11.73 16.6215 1.0 1625813 Maybridge4_004038 CCN(CC)c1ccc(NC(=O)c2ccc(Cl)cc2)c(n1)N(CC)CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H13 compound treatment 0.24 0.0113 1.55 0.241 0.0102 1.47 2.1408 0.9996 3179643 Maybridge4_004039 CCOC(=O)c1cc(CSc2cccc(c2)C(F)(F)F)c3OCOCc3c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H14 compound treatment 0.252 0.0233 3.21 0.244 0.0132 1.91 3.6195 0.969 3064760 Maybridge4_004040 Cc1ccc(SCCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H15 compound treatment 0.221 -0.00775 -1.07 0.222 -0.0088 -1.27 -1.6559 -0.9964 1714044 Maybridge4_004041 O=C1CC(Sc2ccccc2N1)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H16 compound treatment 0.24 0.0113 1.55 0.234 0.0032 0.46 1.4258 0.8793 3179644 Maybridge4_004042 CNC(=S)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H17 compound treatment 0.221 -0.00775 -1.07 0.224 -0.0068 -0.98 -1.4516 -0.9991 3064761 Maybridge4_004043 FC(F)(F)c1ccccc1NC(=S)N2CCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H18 compound treatment 0.248 0.0193 2.66 0.242 0.0112 1.62 3.0244 0.9716 3179645 Maybridge4_004044 Cc1ccc(SCc2cccc(c2)C(=O)N3CCN(CC3)c4ncccc4C(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H19 compound treatment 0.222 -0.00675 -0.93 0.222 -0.0088 -1.27 -1.5582 -0.9884 3064762 Maybridge4_004045 FC(F)(F)C(CNC(=O)Nc1ccccc1)c2ccc[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H20 compound treatment 0.241 0.0123 1.69 0.241 0.0102 1.47 2.2385 0.9976 3179646 Maybridge4_004046 FC(F)(F)Oc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H21 compound treatment 0.224 -0.00475 -0.66 0.224 -0.0068 -0.98 -1.1586 -0.9808 1471144 Maybridge4_004047 Cc1nc(sc1C(=O)Oc2ccc(Cl)cc2)C(=O)Oc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H22 compound treatment 0.219 -0.00975 -1.35 0.221 -0.0098 -1.42 -1.9534 -0.9997 3179647 Maybridge4_004048 CC(C)(C)C(=O)C(Cc1c(F)cccc1Cl)C(=O)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H23 mock treatment 0.229 2.5E-4 0.03 0.23 -8.0E-4 -0.12 -0.0573 -0.475 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 H24 positive control 0.233 0.00425 0.59 0.235 0.0042 0.61 0.8442 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I01 compound treatment 0.225 -0.00375 -0.52 0.227 -0.0038 -0.55 -0.7545 -0.9996 3064764 Maybridge4_004049 Cc1nn(C)c2sc(cc12)C(=O)NC3CCCCNC3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I02 compound treatment 0.273 0.0442 6.11 0.288 0.0572 8.26 10.165 0.989 3179648 Maybridge4_004050 FC(F)(F)c1ccc(cc1)C2N(CCc3sccc23)C(=O)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I03 compound treatment 0.242 0.0133 1.83 0.241 0.0102 1.47 2.3362 0.9942 3179649 Maybridge4_004051 CC1(C)CCc2cc(ccc2O1)S(=O)(=O)NCc3ccc(cc3)S(=O)(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I04 compound treatment 0.238 0.00925 1.28 0.235 0.0042 0.61 1.3326 0.942 3064766 Maybridge4_004052 NNC(=O)c1ncoc1c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I05 compound treatment 0.295 0.0663 9.15 0.299 0.0682 9.85 13.4376 0.9993 3064767 Maybridge4_004053 Cc1cc(C)cc(NC(=O)NCc2csc(n2)c3cccs3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I06 compound treatment 0.233 0.00425 0.59 0.234 0.0032 0.46 0.742 0.993 1598083 Maybridge4_004054 NNC(=O)CS(=O)(=O)Cc1ccc(cc1)c2csnn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I07 compound treatment 0.231 0.00225 0.31 0.227 -0.0038 -0.55 -0.1683 -0.2669 3179650 Maybridge4_004055 O=C(NCc1ccc2OCCc2c1)c3ccc4nsnc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I08 compound treatment 0.268 0.0393 5.42 0.271 0.0402 5.81 7.9402 0.9994 1651781 Maybridge4_004056 CC(C)(C)c1csc(n1)c2sccc2COc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I09 compound treatment 0.247 0.0182 2.52 0.252 0.0212 3.06 3.9481 0.9953 3179651 Maybridge4_004057 Cn1nc(cc1C(=O)NCc2ccc(cc2)c3cccs3)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I10 compound treatment 0.247 0.0182 2.52 0.269 0.0382 5.52 5.6845 0.937 1154669 Maybridge4_004058 Cc1nn(cc1c2nsc(Nc3ccccc3)n2)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I11 compound treatment 0.219 -0.00975 -1.35 0.219 -0.0118 -1.7 -2.1577 -0.9932 3179736 Maybridge4_004059 CN1CCOc2cc(ccc12)S(=O)(=O)NCc3nn(nc3C)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I12 compound treatment 0.241 0.0123 1.69 0.24 0.0092 1.33 2.1363 0.9928 3064768 Maybridge4_004060 Fc1ccc(NC(=O)NC(=O)c2csc(n2)c3ccc(cc3Cl)C(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I13 compound treatment 0.234 0.00525 0.73 0.233 0.0022 0.32 0.7376 0.9314 3179737 Maybridge4_004061 Fc1cc(C(=O)NCc2ccc(cc2)N3CCOCC3)c4OCOCc4c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I14 compound treatment 0.233 0.00425 0.59 0.238 0.0072 1.04 1.1506 0.9634 3179738 Maybridge4_004062 Cc1cc(NC(=O)/C(=C/c2cccs2)/c3ccsc3)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I15 compound treatment 0.318 0.0892 12.33 0.319 0.0882 12.74 17.7272 0.9999 3064816 Maybridge4_004063 COC(=O)C/1=NN(C(=O)\C1=N/O)c2c(C)cccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I16 compound treatment 0.338 0.109 15.09 0.336 0.105 15.2 21.4173 1.0 3064817 Maybridge4_004064 COC(=O)C/1=NN(C(=O)\C1=C/N(C)C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I17 compound treatment 0.232 0.00325 0.45 0.237 0.0062 0.9 0.9507 0.949 3064818 Maybridge4_004065 FC(F)(F)c1cc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)cc(c1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I18 compound treatment 0.228 -7.5E-4 -0.1 0.23 -8.0E-4 -0.12 -0.155 -0.9985 3064819 Maybridge4_004066 OC(=O)c1coc2CCC/C(=N\N3CCCCC3)/c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I19 compound treatment 0.221 -0.00775 -1.07 0.22 -0.0108 -1.56 -1.8602 -0.9831 1604639 Maybridge4_004067 CNC(=S)NCc1ccc(cc1)c2csnn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I20 compound treatment 0.266 0.0372 5.15 0.258 0.0272 3.93 6.417 0.9911 3064820 Maybridge4_004068 FC(F)(F)c1cccc(/C=N/Cc2ccc(s2)c3cccs3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I21 compound treatment 0.231 0.00225 0.31 0.233 0.0022 0.32 0.4445 0.9999 3064821 Maybridge4_004069 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)Oc2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I22 compound treatment 0.355 0.126 17.44 0.361 0.13 18.81 25.6315 0.9993 3064822 Maybridge4_004070 COc1cc(/C=C\2/N=C(C)OC2=O)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I23 mock treatment 0.232 0.00325 0.45 0.233 0.0022 0.32 0.5422 0.9857 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 I24 positive control 0.233 0.00425 0.59 0.236 0.0052 0.75 0.9463 0.9926 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J01 compound treatment 0.227 -0.00175 -0.24 0.23 -8.0E-4 -0.12 -0.2527 -0.9429 3064823 Maybridge4_004071 CSc1cc(n[nH]1)c2nccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J02 compound treatment 0.273 0.0442 6.11 0.306 0.0752 10.86 12.0035 0.963 3179739 Maybridge4_004072 CC(C)c1ccc(C)c2c(/C=C(/C#N)\S(=O)(=O)C)cc(C)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J03 compound treatment 0.25 0.0213 2.94 0.257 0.0262 3.78 4.7519 0.9921 3064824 Maybridge4_004073 Nc1nc2c(c(sc2s1)C(F)(F)F)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J04 compound treatment 0.219 -0.00975 -1.35 0.223 -0.0078 -1.13 -1.7491 -0.9961 3179740 Maybridge4_004074 NC(=S)Nc1ccc(cc1Cl)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J05 compound treatment 0.226 -0.00275 -0.38 0.225 -0.0058 -0.84 -0.861 -0.936 3179741 Maybridge4_004075 COC(=O)c1sc(c(c1S(=O)(=O)N2CCOCC2)c3ccccc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J06 compound treatment 0.225 -0.00375 -0.52 0.227 -0.0038 -0.55 -0.7545 -0.9996 3064825 Maybridge4_004076 CC(C)N(C(C)C)C(=O)c1ccc(cc1)c2ccccc2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J07 compound treatment 0.224 -0.00475 -0.66 0.224 -0.0068 -0.98 -1.1586 -0.9808 1125107 Maybridge4_004077 Clc1snnc1CN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J08 compound treatment 0.234 0.00525 0.73 0.232 0.0012 0.17 0.6354 0.8521 3179742 Maybridge4_004078 Clc1ccc(Sc2ccc(C#N)cn2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J09 compound treatment 0.229 2.5E-4 0.03 0.231 2.0E-4 0.03 0.0448 0.9961 3179743 Maybridge4_004079 COc1cc(cc(OC)c1OC)C(=O)OC(Cc2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J10 compound treatment 0.638 0.409 56.54 0.638 0.407 58.82 81.5694 0.9998 1420510 Maybridge4_004080 NC(=S)c1nc(oc1N)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J11 compound treatment 0.231 0.00225 0.31 0.232 0.0012 0.17 0.3424 0.962 3064826 Maybridge4_004081 CCOC(=O)Cc1csc(n1)c2ncc(cc2Cl)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J12 compound treatment 0.237 0.00825 1.14 0.241 0.0102 1.47 1.8477 0.9919 1571322 Maybridge4_004082 CCN(CC)c1ccc(NC(=O)C2CCCCC2)c(n1)N(CC)CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J13 compound treatment 0.225 -0.00375 -0.52 0.226 -0.0048 -0.69 -0.8566 -0.9897 3064827 Maybridge4_004083 CC(C)(C)Cc1nc(no1)C2(CC2)c3ccc(Cl)cc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J14 compound treatment 0.322 0.0933 12.88 0.292 0.0612 8.84 15.3602 0.9831 3179744 Maybridge4_004084 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)cc1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J15 compound treatment 0.277 0.0483 6.67 0.275 0.0442 6.38 9.2279 0.9998 1672501 Maybridge4_004085 O=C(NC(=O)N1CCCC1)C2CCN(CC2)c3cnc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J16 compound treatment 0.261 0.0323 4.46 0.247 0.0162 2.34 4.8051 0.9548 3064828 Maybridge4_004086 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J17 compound treatment 0.223 -0.00575 -0.79 0.226 -0.0048 -0.69 -1.052 -0.9977 1716306 Maybridge4_004087 O=C(C1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J18 compound treatment 0.225 -0.00375 -0.52 0.224 -0.0068 -0.98 -1.0609 -0.9553 1727489 Maybridge4_004088 Cc1ccc(F)cc1N2CC(CC2=O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J19 compound treatment 0.243 0.0143 1.97 0.24 0.0092 1.33 2.3317 0.9817 3179745 Maybridge4_004089 Clc1ccc(/C=C/2\COC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J20 compound treatment 0.248 0.0193 2.66 0.258 0.0272 3.93 4.6587 0.9819 1700558 Maybridge4_004090 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)c3nc(no3)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J21 compound treatment 0.227 -0.00175 -0.24 0.227 -0.0038 -0.55 -0.5591 -0.9321 3064829 Maybridge4_004091 Fc1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J22 compound treatment 0.228 -7.5E-4 -0.1 0.228 -0.0028 -0.4 -0.3593 -0.8605 3064830 Maybridge4_004092 CC(C)(C)c1nnc(o1)c2cccc(NS(=O)(=O)c3ccc(s3)c4ccon4)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J23 mock treatment 0.231 0.00225 0.31 0.231 2.0E-4 0.03 0.2402 0.7695 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 J24 positive control 0.234 0.00525 0.73 0.235 0.0042 0.61 0.9418 0.9961 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K01 compound treatment 0.226 -0.00275 -0.38 0.228 -0.0028 -0.4 -0.5546 -0.9995 3179746 Maybridge4_004093 Clc1ccc(cc1)S(=O)(=O)NC2CCCCNC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K02 compound treatment 0.248 0.0193 2.66 0.247 0.0162 2.34 3.5351 0.998 3179747 Maybridge4_004094 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc(c2)c3nnco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K03 compound treatment 0.235 0.00625 0.86 0.232 0.0012 0.17 0.7331 0.8324 3064831 Maybridge4_004095 O=S(=O)(NCC1COc2ccccc2O1)c3ccc(nc3)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K04 compound treatment 0.227 -0.00175 -0.24 0.235 0.0042 0.61 0.258 0.3951 1348923 Maybridge4_004096 Cc1cc(NC(=O)CCOc2ccc(F)cc2)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K05 compound treatment 0.222 -0.00675 -0.93 0.221 -0.0098 -1.42 -1.6603 -0.9795 3179748 Maybridge4_004097 Cc1cc(c(C)o1)S(=O)(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K06 compound treatment 0.231 0.00225 0.31 0.232 0.0012 0.17 0.3424 0.962 1281685 Maybridge4_004098 NC(=O)c1cnc2SCCn2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K07 compound treatment 0.216 -0.0127 -1.76 0.216 -0.0148 -2.14 -2.7572 -0.9954 3064832 Maybridge4_004099 COc1ccc(cc1)C(=O)NCc2ccc3OCCc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K08 compound treatment 0.238 0.00925 1.28 0.246 0.0152 2.2 2.4561 0.9668 3179749 Maybridge4_004100 CC(C)(C)c1csc(n1)c2sccc2CS(=O)(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K09 compound treatment 0.245 0.0163 2.24 0.257 0.0262 3.78 4.2635 0.9689 3179750 Maybridge4_004101 COc1ccccc1CC(=O)NCc2nn(nc2C)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K10 compound treatment 0.24 0.0113 1.55 0.233 0.0022 0.32 1.3237 0.8344 3064834 Maybridge4_004102 FC(F)(F)c1ccc(SCCS(=O)(=O)CCSc2ccc(cn2)C(F)(F)F)nc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K11 compound treatment 0.217 -0.0118 -1.62 0.218 -0.0128 -1.85 -2.4552 -0.9979 3179751 Maybridge4_004103 Cc1noc(C)c1S(=O)(=O)NCc2nn(nc2C)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K12 compound treatment 0.219 -0.00975 -1.35 0.22 -0.0108 -1.56 -2.0555 -0.9973 3064714 Maybridge4_004104 OC(=O)c1ncoc1c2cccc(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K13 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 1121050 Maybridge4_004105 CCOC(=O)c1c(NC(=O)C)nc(SC)n1Cc2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K14 compound treatment 0.35 0.121 16.75 0.321 0.0902 13.03 21.0575 0.9923 3179752 Maybridge4_004106 FC(F)(F)c1ccc(SC(=O)/C(=C\c2cccs2)/c3ccsc3)nc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K15 compound treatment 0.279 0.0503 6.94 0.279 0.0482 6.96 9.8319 1.0 3064716 Maybridge4_004107 CCOC(=O)c1n[nH]c(=S)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K16 compound treatment 0.238 0.00925 1.28 0.237 0.0062 0.9 1.5369 0.9849 3179753 Maybridge4_004108 COC(=O)c1nn(c2ccccc2)c3oc(=O)cc(C)c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K17 compound treatment 0.226 -0.00275 -0.38 0.233 0.0022 0.32 -0.0439 -0.0887 3064717 Maybridge4_004109 CC(C)(C)S(=O)(=O)/C(=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K18 compound treatment 0.27 0.0413 5.7 0.263 0.0322 4.65 7.3185 0.9949 3179754 Maybridge4_004110 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)c4cccc(c4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K19 compound treatment 0.237 0.00825 1.14 0.231 2.0E-4 0.03 0.8264 0.7248 3064769 Maybridge4_004111 CC1=NN(C(=O)C1)c2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K20 compound treatment 0.242 0.0133 1.83 0.237 0.0062 0.9 1.9276 0.9459 1351476 Maybridge4_004112 Fc1ccccc1NC(=O)NCc2sccc2COc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K21 compound treatment 0.226 -0.00275 -0.38 0.222 -0.0088 -1.27 -1.1675 -0.88 3064771 Maybridge4_004113 CCCC1N(CCc2sccc12)C(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K22 compound treatment 0.227 -0.00175 -0.24 0.228 -0.0028 -0.4 -0.4569 -0.9697 3179755 Maybridge4_004114 COc1cc(/C=C(\NC(=O)C)/C(=O)O)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K23 mock treatment 0.23 0.00125 0.17 0.231 2.0E-4 0.03 0.1425 0.8141 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 K24 positive control 0.232 0.00325 0.45 0.232 0.0012 0.17 0.4401 0.9143 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L01 compound treatment 0.256 0.0273 3.76 0.259 0.0282 4.07 5.5423 0.9992 3064772 Maybridge4_004115 FC(F)(F)c1sc(cc1c2ccccc2)C(=O)Oc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L02 compound treatment 0.349 0.12 16.61 0.355 0.124 17.94 24.4325 0.9993 3179756 Maybridge4_004116 NC(=S)c1ccc(s1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L03 compound treatment 0.252 0.0233 3.21 0.254 0.0232 3.35 4.6408 0.9998 3179757 Maybridge4_004117 COc1ccc(SCc2nsc(Sc3ccc(OC)cc3)n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L04 compound treatment 0.253 0.0243 3.35 0.263 0.0322 4.65 5.6578 0.987 3064773 Maybridge4_004118 OC(=O)c1c-2c(CSc3ccc(Cl)cc32)nc4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L05 compound treatment 0.226 -0.00275 -0.38 0.224 -0.0068 -0.98 -0.9632 -0.9146 3179758 Maybridge4_004119 CSC(=N)Nc1csc(c1c2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L06 compound treatment 0.342 0.113 15.65 0.359 0.128 18.52 24.1573 0.9965 3179759 Maybridge4_004120 O=C/1Nc2ccccc2\C1=C/c3ccccc3N4CCN(Cc5ccccc5)CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L07 compound treatment 0.265 0.0362 5.01 0.265 0.0342 4.94 7.0343 1.0 3064774 Maybridge4_004121 NC(=S)c1cc(c(s1)C(F)(F)F)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L08 compound treatment 0.254 0.0253 3.49 0.254 0.0232 3.35 4.8362 0.9998 3064775 Maybridge4_004122 CCOC(=O)Cc1c(C#N)c(N)sc1C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L09 compound treatment 0.222 -0.00675 -0.93 0.225 -0.0058 -0.84 -1.2518 -0.9986 3179760 Maybridge4_004123 FC(F)(F)C(Cc1ccccc1)OC(=O)c2ccc(Cl)cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L10 compound treatment 0.285 0.0563 7.77 0.278 0.0472 6.82 10.3159 0.9979 3064776 Maybridge4_004124 CC(C)(C)c1ccc(s1)C(=O)Nc2ccc(cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L11 compound treatment 0.275 0.0462 6.39 0.27 0.0392 5.66 8.5219 0.9982 3178169 Maybridge4_004125 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSc4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L12 compound treatment 0.264 0.0352 4.87 0.259 0.0282 4.07 6.3238 0.9961 3178170 Maybridge4_004126 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)c4cccs4)cn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L13 compound treatment 0.236 0.00725 1.0 0.233 0.0022 0.32 0.9329 0.8878 3064777 Maybridge4_004127 FC(F)(F)c1ccnc(c1)c2ccc(s2)S(=O)(=O)N3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L14 compound treatment 0.264 0.0352 4.87 0.261 0.0302 4.36 6.5281 0.9985 3064778 Maybridge4_004128 CC1(C)OC(=O)C(=Cc2cccn2c3ccc(cc3)C(F)(F)F)C(=O)O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L15 compound treatment 0.231 0.00225 0.31 0.232 0.0012 0.17 0.3424 0.962 3178171 Maybridge4_004129 Cc1onc(c1NC(=O)OCCOc2cc(ccn2)C(F)(F)F)c3c(Cl)cccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L16 compound treatment 0.264 0.0352 4.87 0.268 0.0372 5.37 7.243 0.9988 3178172 Maybridge4_004130 CC(C)Cc1ccc(cc1)C(C)C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L17 compound treatment 0.251 0.0222 3.07 0.26 0.0292 4.22 5.156 0.9879 1466123 Maybridge4_004131 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L18 compound treatment 0.377 0.148 20.48 0.381 0.15 21.7 29.8234 0.9996 3178173 Maybridge4_004132 CS(=O)(=O)/C(=C/c1cccn1c2ccc(OC(F)(F)F)cc2)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L19 compound treatment 0.219 -0.00975 -1.35 0.221 -0.0098 -1.42 -1.9534 -0.9997 3064779 Maybridge4_004133 Clc1ccc(C(=O)n2cc3COCCc3n2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L20 compound treatment 0.236 0.00725 1.0 0.239 0.0082 1.18 1.5458 0.9965 3178174 Maybridge4_004134 CC(C)(C)c1cc(n(n1)c2ccc(cc2)C(=O)NN)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L21 compound treatment 0.214 -0.0147 -2.04 0.214 -0.0168 -2.43 -3.1568 -0.9962 3064780 Maybridge4_004135 OC(=O)CCc1ccc(Cl)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L22 compound treatment 0.269 0.0403 5.56 0.265 0.0342 4.94 7.4251 0.9983 1339700 Maybridge4_004136 Cc1onc(c1c2nc(CSc3nc4ccccc4[nH]3)no2)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L23 mock treatment 0.229 2.5E-4 0.03 0.231 2.0E-4 0.03 0.0448 0.9961 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 L24 positive control 0.228 -7.5E-4 -0.1 0.231 2.0E-4 0.03 -0.0528 -0.4912 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M01 compound treatment 0.228 -7.5E-4 -0.1 0.227 -0.0038 -0.55 -0.4614 -0.826 3178175 Maybridge4_004137 CCc1ccc(cc1)S(=O)(=O)NC2CCCCNC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M02 compound treatment 0.411 0.182 25.18 0.404 0.173 25.02 35.4939 1.0 3064835 Maybridge4_004138 CC/1Sc2ccc(Cl)cc2C(=O)\C1=C\N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M03 compound treatment 0.227 -0.00175 -0.24 0.225 -0.0058 -0.84 -0.7634 -0.8754 3178176 Maybridge4_004139 O=S(=O)(N(Cc1ccccn1)Cc2ccccn2)c3ccc(nc3)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M04 compound treatment 0.223 -0.00575 -0.79 0.225 -0.0058 -0.84 -1.1541 -0.9996 3064836 Maybridge4_004140 Cn1cnnc1SCc2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M05 compound treatment 0.23 0.00125 0.17 0.228 -0.0028 -0.4 -0.1639 -0.3726 3178177 Maybridge4_004141 O=C(N1CCCCCC1)c2ccc(nc2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M06 compound treatment 0.234 0.00525 0.73 0.234 0.0032 0.46 0.8397 0.9763 3064837 Maybridge4_004142 COC(=O)c1cc(C)cc(=O)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M07 compound treatment 0.219 -0.00975 -1.35 0.22 -0.0108 -1.56 -2.0555 -0.9973 3064839 Maybridge4_004143 Fc1ccc(cc1F)S(=O)(=O)NCc2ccc3OCCc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M08 compound treatment 0.226 -0.00275 -0.38 0.229 -0.0018 -0.26 -0.4525 -0.9829 1167482 Maybridge4_004144 Cc1nc(C)c(o1)c2ccnc(n2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M09 compound treatment 0.241 0.0123 1.69 0.243 0.0122 1.76 2.4428 0.9998 3178178 Maybridge4_004145 CN(C)c1ccc(cc1)C(=O)NCc2nn(nc2C)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M10 compound treatment 0.305 0.0762 10.53 0.311 0.0802 11.58 15.6402 0.9989 1335790 Maybridge4_004146 CN(C)c1c(F)cc(cc1F)C(=O)NC(=O)NCc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M11 compound treatment 0.22 -0.00875 -1.21 0.223 -0.0078 -1.13 -1.6514 -0.9994 3178179 Maybridge4_004147 COc1ccc(OC)c(c1)S(=O)(=O)NCc2nn(nc2C)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M12 compound treatment 0.392 0.163 22.55 0.371 0.14 20.25 30.2673 0.9986 3064841 Maybridge4_004148 CN(C)c1c(/C=C(/C#N)\S(=O)(=O)C)cc(/C=C(/C#N)\S(=O)(=O)C)c(N(C)C)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M13 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 3178180 Maybridge4_004149 CSc1nsc(SC)c1C(=O)NC(=O)N2CCSCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M14 compound treatment 0.219 -0.00975 -1.35 0.219 -0.0118 -1.7 -2.1577 -0.9932 1166894 Maybridge4_004150 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)N3CCSCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M15 compound treatment 0.272 0.0432 5.98 0.264 0.0332 4.8 7.616 0.9941 3064844 Maybridge4_004151 COC(=O)c1sc(cc1CS(=O)(=O)c2cc(C)c(Cl)cc2C)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M16 compound treatment 0.334 0.105 14.54 0.304 0.0732 10.57 17.7582 0.9878 3178181 Maybridge4_004152 Sc1nccc(n1)c2ccc(s2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M17 compound treatment 0.268 0.0393 5.42 0.272 0.0412 5.95 8.0423 0.9989 1462127 Maybridge4_004153 Fc1ccc(C(=O)Nc2ccc(cc2)c3cnco3)c(F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M18 compound treatment 0.275 0.0462 6.39 0.264 0.0332 4.8 7.909 0.99 3178182 Maybridge4_004154 Cc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M19 compound treatment 0.232 0.00325 0.45 0.234 0.0032 0.46 0.6443 0.9999 1245747 Maybridge4_004155 Clc1ccc(cc1)C2=NCCc3sccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M20 compound treatment 0.232 0.00325 0.45 0.234 0.0032 0.46 0.6443 0.9999 3178183 Maybridge4_004156 Clc1ccc(OCc2ccsc2Cn3cccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M21 compound treatment 0.218 -0.0107 -1.49 0.22 -0.0108 -1.56 -2.1532 -0.9997 1431141 Maybridge4_004157 CCCC1N(CCc2sccc12)C(=O)c3cc(OC)cc(OC)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M22 compound treatment 0.26 0.0313 4.32 0.257 0.0262 3.78 5.7288 0.9978 3178184 Maybridge4_004158 Clc1ccc(SC(=O)c2ccc(s2)c3cccs3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M23 mock treatment 0.229 2.5E-4 0.03 0.233 0.0022 0.32 0.2491 0.7794 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 M24 positive control 0.224 -0.00475 -0.66 0.227 -0.0038 -0.55 -0.8521 -0.9961 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N01 compound treatment 0.223 -0.00575 -0.79 0.223 -0.0078 -1.13 -1.3584 -0.9854 3064890 Maybridge4_004159 C/C(=N\O)/c1cc(c(s1)C(F)(F)F)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N02 compound treatment 0.397 0.168 23.24 0.345 0.114 16.5 28.1002 0.9859 3178185 Maybridge4_004160 CC(C)(C)c1csc(n1)c2ccc(s2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N03 compound treatment 0.257 0.0283 3.9 0.257 0.0262 3.78 5.4357 0.9999 3064891 Maybridge4_004161 FC(F)(F)c1sc(COC(=O)Nc2ccccc2)cc1c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N04 compound treatment 0.215 -0.0138 -1.9 0.216 -0.0148 -2.14 -2.8549 -0.9983 3178186 Maybridge4_004162 FC(F)(F)c1ccc(Cl)c(c1)c2ccc(o2)C(C3C(=O)CCCC3=O)C4C(=O)CCCC4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N05 compound treatment 0.23 0.00125 0.17 0.23 -8.0E-4 -0.12 0.0404 0.1944 3064893 Maybridge4_004163 COc1ccc(SCc2cc3c(F)c(F)c(F)c(F)c3o2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N06 compound treatment 0.258 0.0293 4.04 0.263 0.0322 4.65 6.1462 0.9975 3178187 Maybridge4_004164 Cc1noc(C)c1C(=O)n2cc3CSc4ccc(F)cc4-c3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N07 compound treatment 0.226 -0.00275 -0.38 0.23 -8.0E-4 -0.12 -0.3504 -0.8823 3064894 Maybridge4_004165 FC(F)(F)/C(=C(\C#N)/c1ccccc1)/Oc2ccc(C#N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N08 compound treatment 0.218 -0.0107 -1.49 0.217 -0.0138 -1.99 -2.4597 -0.9895 3178188 Maybridge4_004166 Cc1oc(N)c(c1C)S(=O)(=O)/C(=C/c2cc(Cl)cc(Cl)c2)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N09 compound treatment 0.224 -0.00475 -0.66 0.233 0.0022 0.32 -0.2393 -0.3282 3178189 Maybridge4_004167 CCOC(=O)c1ccc2C(=O)/C(=C/c3ccc(Cl)cc3Cl)/CCc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N10 compound treatment 0.219 -0.00975 -1.35 0.222 -0.0088 -1.27 -1.8513 -0.9996 1967416 Maybridge4_004168 OC(=O)CCC(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N11 compound treatment 0.252 0.0233 3.21 0.248 0.0172 2.48 4.028 0.9919 3064896 Maybridge4_004169 Clc1ccc(SCc2csc(n2)c3ccsc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N12 compound treatment 0.217 -0.0118 -1.62 0.219 -0.0118 -1.7 -2.3531 -0.9997 3178190 Maybridge4_004170 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)/C=C/c4ccccc4)cn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N13 compound treatment 0.225 -0.00375 -0.52 0.228 -0.0028 -0.4 -0.6523 -0.9925 3064897 Maybridge4_004171 CN(C)/C=N/C(=S)N1CCOCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N14 compound treatment 0.218 -0.0107 -1.49 0.216 -0.0148 -2.14 -2.5618 -0.9842 3178191 Maybridge4_004172 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCc4c([nH]c5ccccc45)C3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N15 compound treatment 0.217 -0.0118 -1.62 0.218 -0.0128 -1.85 -2.4552 -0.9979 1192815 Maybridge4_004173 O=C(NC(=S)Nc1ccncc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N16 compound treatment 0.221 -0.00775 -1.07 0.22 -0.0108 -1.56 -1.8602 -0.9831 3064898 Maybridge4_004174 CS(=O)(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N17 compound treatment 0.221 -0.00775 -1.07 0.227 -0.0038 -0.55 -1.1452 -0.9518 1131475 Maybridge4_004175 Clc1ccc(NC(=O)N2CCC(CC2)C(=O)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N18 compound treatment 0.22 -0.00875 -1.21 0.222 -0.0088 -1.27 -1.7536 -0.9997 1346023 Maybridge4_004176 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccc(cc2)c3csnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N19 compound treatment 0.221 -0.00775 -1.07 0.222 -0.0088 -1.27 -1.6559 -0.9964 3178192 Maybridge4_004177 S=C(SCc1ncon1)N2CCSCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N20 compound treatment 0.222 -0.00675 -0.93 0.227 -0.0038 -0.55 -1.0475 -0.9681 3178193 Maybridge4_004178 Cc1ccc(C)n1CCSCc2c(C)cc(C)cc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N21 compound treatment 0.217 -0.0118 -1.62 0.221 -0.0098 -1.42 -2.1488 -0.9977 1202142 Maybridge4_004179 CCOC(=O)c1c(C)nn(c1C)c2ncccc2NC(=O)CCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N22 compound treatment 0.223 -0.00575 -0.79 0.226 -0.0048 -0.69 -1.052 -0.9977 1591050 Maybridge4_004180 CCOC(=O)c1[nH]c2ccc(cc2c1CCC(=O)O)C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N23 mock treatment 0.226 -0.00275 -0.38 0.23 -8.0E-4 -0.12 -0.3504 -0.8823 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 N24 positive control 0.225 -0.00375 -0.52 0.229 -0.0018 -0.26 -0.5502 -0.9492 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O01 compound treatment 0.238 0.00925 1.28 0.239 0.0082 1.18 1.7411 0.9993 3178270 Maybridge4_004181 COc1cc2CCN(Cc2cc1OC)C(=O)c3sc(nc3C)c4cnccn4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O02 compound treatment 0.224 -0.00475 -0.66 0.223 -0.0078 -1.13 -1.2607 -0.9669 1317839 Maybridge4_004182 CC(C)(C)c1ccc(s1)C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O03 compound treatment 0.25 0.0213 2.94 0.245 0.0142 2.05 3.5262 0.9846 3064900 Maybridge4_004183 COc1ccc(cc1)n2ncc(C(=O)Nc3ccc4nccnc4c3)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O04 compound treatment 0.259 0.0302 4.18 0.259 0.0282 4.07 5.8354 0.9999 3178271 Maybridge4_004184 N/C(=N/O)/c1cnc2SCCn2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O05 compound treatment 0.226 -0.00275 -0.38 0.227 -0.0038 -0.55 -0.6568 -0.9839 3178272 Maybridge4_004185 O=C(N1CCSCC1)c2ccc(nc2)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O06 compound treatment 0.228 -7.5E-4 -0.1 0.228 -0.0028 -0.4 -0.3593 -0.8605 3064901 Maybridge4_004186 NC(=S)c1ccc(cc1Cl)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O07 compound treatment 0.244 0.0153 2.11 0.245 0.0142 2.05 2.9401 0.9999 3178273 Maybridge4_004187 O=S(=O)(NCc1ccc(cc1)c2cccs2)c3ccc(nc3)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O08 compound treatment 0.361 0.132 18.27 0.451 0.22 31.81 35.4101 0.9654 3064932 Maybridge4_004188 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)C)c(F)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O09 compound treatment 0.22 -0.00875 -1.21 0.221 -0.0098 -1.42 -1.8557 -0.9969 3178274 Maybridge4_004189 Cc1nn(nc1CNC(=O)c2cccs2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O10 compound treatment 0.258 0.0293 4.04 0.26 0.0292 4.22 5.8398 0.9998 3178275 Maybridge4_004190 CN(C)c1c(F)cc(cc1F)C(=O)NC(=O)NC2=NCCS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O11 compound treatment 0.216 -0.0127 -1.76 0.216 -0.0148 -2.14 -2.7572 -0.9954 3064933 Maybridge4_004191 Cc1noc(C)c1NC(=O)NCc2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O12 compound treatment 0.224 -0.00475 -0.66 0.227 -0.0038 -0.55 -0.8521 -0.9961 3064934 Maybridge4_004192 NNC(=O)c1cc2sccc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O13 compound treatment 0.256 0.0273 3.76 0.264 0.0332 4.8 6.053 0.9928 3178276 Maybridge4_004193 CSc1nsc(SC)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O14 compound treatment 0.215 -0.0138 -1.9 0.216 -0.0148 -2.14 -2.8549 -0.9983 1408005 Maybridge4_004194 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)Nc3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O15 compound treatment 0.221 -0.00775 -1.07 0.222 -0.0088 -1.27 -1.6559 -0.9964 3064936 Maybridge4_004195 COC(=O)c1sc(cc1CS(=O)(=O)c2ccccn2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O16 compound treatment 0.284 0.0553 7.63 0.297 0.0662 9.56 12.1588 0.9938 3178277 Maybridge4_004196 COc1ccc(cc1OC)S(=O)(=O)n2nccc2c3ccc(s3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O17 compound treatment 0.281 0.0522 7.22 0.27 0.0392 5.66 9.108 0.9928 3064939 Maybridge4_004197 Clc1ccc(NC(=S)Nc2ccc(cc2)c3csnn3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O18 compound treatment 0.3 0.0712 9.84 0.272 0.0412 5.95 11.1683 0.971 3178278 Maybridge4_004198 Clc1cccc(Cl)c1C(=O)NCc2ccc(s2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O19 compound treatment 0.217 -0.0118 -1.62 0.218 -0.0128 -1.85 -2.4552 -0.9979 3064941 Maybridge4_004199 CNC(=S)N1CCc2sccc2C1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O20 compound treatment 0.242 0.0133 1.83 0.247 0.0162 2.34 2.949 0.9926 3178279 Maybridge4_004200 CS/C(=N\C#N)/NCc1sccc1COc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O21 compound treatment 0.216 -0.0127 -1.76 0.216 -0.0148 -2.14 -2.7572 -0.9954 1659450 Maybridge4_004201 O=C(NC(=O)c1ccc(cc1)c2csnn2)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O22 compound treatment 0.276 0.0473 6.53 0.267 0.0362 5.23 8.3132 0.994 3178280 Maybridge4_004202 CN(C)/C=N\C(=S)c1sccc1CSc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O23 mock treatment 0.229 2.5E-4 0.03 0.229 -0.0018 -0.26 -0.1594 -0.6078 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 O24 positive control 0.226 -0.00275 -0.38 0.226 -0.0048 -0.69 -0.7589 -0.9599 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P01 compound treatment 0.248 0.0193 2.66 0.249 0.0182 2.63 3.7394 1.0 1411380 Maybridge4_004203 COC(=O)c1cc(=O)n2ccccc2c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P02 compound treatment 0.365 0.136 18.82 0.371 0.14 20.25 27.6297 0.9993 3178281 Maybridge4_004204 CN(C)/C=N/C(=S)c1ccc(s1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P03 compound treatment 0.254 0.0253 3.49 0.252 0.0212 3.06 4.6319 0.9979 3178282 Maybridge4_004205 CCOC(=O)c1c(CS(=O)(=O)Cc2ccc(Cl)cc2)oc3c(F)c(F)c(F)c(F)c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P04 compound treatment 0.218 -0.0107 -1.49 0.222 -0.0088 -1.27 -1.949 -0.997 1195874 Maybridge4_004206 COc1ccc(CN(Cc2cc(OC)c(OC)c(OC)c2)C(=O)C(C)(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P05 compound treatment 0.243 0.0143 1.97 0.239 0.0082 1.18 2.2296 0.9704 3178283 Maybridge4_004207 COC(=O)c1sc(c(c1S(=O)(=O)NC(C)(C)C)c2ccccc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P06 compound treatment 0.292 0.0633 8.74 0.292 0.0612 8.84 12.4296 1.0 3064943 Maybridge4_004208 OC1=C(C(=O)c2ccccc12)c3cc(Cl)cc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P07 compound treatment 0.28 0.0512 7.08 0.281 0.0502 7.25 10.1338 0.9999 3064944 Maybridge4_004209 CSc1ccc(/C=C\2/C(=NN(C)C2=O)C)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P08 compound treatment 0.22 -0.00875 -1.21 0.221 -0.0098 -1.42 -1.8557 -0.9969 1179765 Maybridge4_004210 Cc1noc(C)c1NC(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P09 compound treatment 0.221 -0.00775 -1.07 0.225 -0.0058 -0.84 -1.3495 -0.9926 3064945 Maybridge4_004211 FC(F)(F)Oc1ccc(NC(=O)C=C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P10 compound treatment 0.239 0.0103 1.42 0.237 0.0062 0.9 1.6346 0.9756 3178284 Maybridge4_004212 CC(C)(C)SCc1cccc(c1)C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P11 compound treatment 0.215 -0.0138 -1.9 0.215 -0.0158 -2.28 -2.957 -0.9958 3178285 Maybridge4_004213 OC(=O)c1cccnc1C(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P12 compound treatment 0.218 -0.0107 -1.49 0.218 -0.0128 -1.85 -2.3575 -0.9941 3178286 Maybridge4_004214 O/N=C/c1ccc(Cl)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P13 compound treatment 0.236 0.00725 1.0 0.237 0.0062 0.9 1.3415 0.9984 3178287 Maybridge4_004215 CC(C)(C)NC(=O)N1CCN(CC1)c2cc(ccn2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P14 compound treatment 0.219 -0.00975 -1.35 0.219 -0.0118 -1.7 -2.1577 -0.9932 3064989 Maybridge4_004216 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=S)NCC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P15 compound treatment 0.233 0.00425 0.59 0.228 -0.0028 -0.4 0.1292 0.1812 3178288 Maybridge4_004217 CN(C(=S)NC(=O)c1ccccc1)c2ccc(OC(F)(F)F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P16 compound treatment 0.225 -0.00375 -0.52 0.226 -0.0048 -0.69 -0.8566 -0.9897 3064991 Maybridge4_004218 FC(F)(F)c1ccc(nc1)N2CCN(CC2)C(=O)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P17 compound treatment 0.262 0.0333 4.59 0.267 0.0362 5.23 6.9455 0.9979 3178289 Maybridge4_004219 Cc1cc(C)n(n1)c2ccc(cc2)n3cccc3/C=C(/C#N)\S(=O)(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P18 compound treatment 0.216 -0.0127 -1.76 0.218 -0.0128 -1.85 -2.5529 -0.9997 3178290 Maybridge4_004220 OC(=O)CCCC(=O)Nc1ccccc1SCc2noc(n2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P19 compound treatment 0.255 0.0262 3.63 0.261 0.0302 4.36 5.6489 0.9958 1467411 Maybridge4_004221 Fc1ccc(CSC(=S)N2CCN(CC2)C(=S)SCc3ccc(F)cc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P20 compound treatment 0.221 -0.00775 -1.07 0.221 -0.0098 -1.42 -1.758 -0.9905 3064993 Maybridge4_004222 CC(C)n1nc(cc1C(C)(C)C)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P21 compound treatment 0.216 -0.0127 -1.76 0.217 -0.0138 -1.99 -2.655 -0.9981 3178291 Maybridge4_004223 Cn1nc(c(c1N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P22 compound treatment 0.248 0.0193 2.66 0.254 0.0232 3.35 4.2501 0.9934 3178292 Maybridge4_004224 COC(=O)c1cc(/C=C/C(=O)N(C2CCCCC2)C(=O)NC3CCCCC3)cn1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P23 mock treatment 0.228 -7.5E-4 -0.1 0.229 -0.0018 -0.26 -0.2571 -0.9186 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2060 P24 positive control 0.231 0.00225 0.31 0.232 0.0012 0.17 0.3424 0.962 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A01 compound treatment 0.297 0.0709 9.8 0.312 0.0819 11.83 15.2923 0.9956 3081891 TimTec1_000353 CCc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A02 compound treatment 0.445 0.219 30.25 0.446 0.216 31.18 43.4366 0.9999 3210254 TimTec1_000354 O=C/1NC(=S)S\C1=C\c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A03 compound treatment 0.246 0.0199 2.75 0.242 0.0119 1.72 3.1605 0.974 3081893 TimTec1_000355 CCOC(=O)c1sc2cc(OC)ccc2c1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A04 compound treatment 0.292 0.0659 9.11 0.269 0.0389 5.62 10.4119 0.973 1428363 TimTec1_000356 CCc1c(C)sc(NC(=O)C2CC3CCC2C3)c1C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A05 compound treatment 0.217 -0.00906 -1.25 0.217 -0.0131 -1.9 -2.2259 -0.9797 3081895 TimTec1_000357 Cc1ccc(C)[n+](CNC(=O)c2ccc(Cl)cc2Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A06 compound treatment 0.217 -0.00906 -1.25 0.215 -0.0151 -2.18 -2.4301 -0.9651 1573927 TimTec1_000358 CCOc1ccc(cc1)C(=O)Nc2cc(C)ccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A07 compound treatment 0.219 -0.00706 -0.98 0.227 -0.00312 -0.45 -1.0091 -0.9387 1174870 TimTec1_000359 OC(=O)c1ccccc1SC(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A08 compound treatment 0.229 0.00294 0.41 0.225 -0.00512 -0.74 -0.2365 -0.2801 3210255 TimTec1_000360 C/C(=N\N)/c1ccc2ccccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A09 compound treatment 0.219 -0.00706 -0.98 0.218 -0.0121 -1.75 -1.9283 -0.9618 3210256 TimTec1_000361 OC(=O)/C=C/c1ccc(cc1)S(=O)(=O)Nc2cccc(c2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A10 compound treatment 0.214 -0.0121 -1.67 0.21 -0.0201 -2.91 -3.2339 -0.9651 1008686 TimTec1_000362 OC(=O)c1cncc(c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A11 compound treatment 0.235 0.00894 1.23 0.241 0.0109 1.57 1.9838 0.9929 1637875 TimTec1_000363 Cc1oc2ccccc2c1c3ccc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A12 compound treatment 0.29 0.0639 8.83 0.288 0.0579 8.36 12.1572 0.9996 1629100 TimTec1_000364 COc1ccc2nc(C)cc(Nc3ccccc3)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A13 compound treatment 0.28 0.0539 7.45 0.268 0.0379 5.47 9.1375 0.9885 3081900 TimTec1_000365 O=C(Oc1nc2ccccc2s1)c3ccccc3C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A14 compound treatment 0.211 -0.0151 -2.08 0.212 -0.0181 -2.62 -3.3227 -0.9935 1265013 TimTec1_000366 COc1ccc(OCC(O)CN2CCN(C)CC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A15 compound treatment 0.216 -0.0101 -1.39 0.218 -0.0121 -1.75 -2.2214 -0.9935 3081958 TimTec1_000367 Cc1nn(C)cc1C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A16 compound treatment 0.34 0.114 15.74 0.34 0.11 15.87 22.3527 1.0 3210257 TimTec1_000368 O=C(NCCOc1ccccc1Cc2ccccc2)c3ccc4CCc5cccc3c54 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A17 compound treatment 0.223 -0.00306 -0.42 0.216 -0.0141 -2.04 -1.7419 -0.836 1435378 TimTec1_000369 O=C(NC1CCCCCCC1)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A18 compound treatment 0.238 0.0119 1.65 0.236 0.00587 0.85 1.7662 0.9523 1651254 TimTec1_000370 Clc1ccc(CCNC(=O)C(c2ccccc2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A19 compound treatment 0.293 0.0669 9.25 0.292 0.0619 8.94 12.8588 0.9999 3210258 TimTec1_000371 COC(=O)C1=C(C)NC(=S)NC1c2cn(nc2c3cccs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A20 compound treatment 0.266 0.0399 5.52 0.271 0.0409 5.9 8.0763 0.9994 1199491 TimTec1_000372 O=C(CNc1ccc(Cc2ccncc2)cc1)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A21 compound treatment 0.211 -0.0151 -2.08 0.211 -0.0191 -2.76 -3.4248 -0.9902 1401884 TimTec1_000373 C(OC1CCCCC1)C2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A22 compound treatment 0.212 -0.0141 -1.94 0.213 -0.0171 -2.47 -3.1229 -0.9929 1357135 TimTec1_000374 Cc1nnc(SCC(=O)N2CCOCC2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A23 mock treatment 0.22 -0.00606 -0.84 0.221 -0.00912 -1.32 -1.5242 -0.976 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 A24 positive control 0.216 -0.0101 -1.39 0.213 -0.0171 -2.47 -2.7321 -0.9629 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B01 compound treatment 0.222 -0.00406 -0.56 0.226 -0.00412 -0.6 -0.8182 -0.9996 3210259 TimTec1_000375 CC(NC(=O)CSc1nnc(c2cccc(F)c2)n1c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B02 compound treatment 0.369 0.143 19.75 0.381 0.151 21.79 29.3734 0.9988 1231283 TimTec1_000376 O=C(C1=NN(C2C1C(=O)N(C2=O)c3ccccc3)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B03 compound treatment 0.227 9.38E-4 0.13 0.228 -0.00212 -0.31 -0.1255 -0.3766 1268796 TimTec1_000377 Nc1nonc1C(=O)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B04 compound treatment 0.219 -0.00706 -0.98 0.229 -0.00112 -0.16 -0.8048 -0.8137 1721792 TimTec1_000378 Cc1ccc(cc1)C(=O)N2CCc3ccccc3C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B05 compound treatment 0.23 0.00394 0.54 0.235 0.00487 0.7 0.8826 0.9919 3081967 TimTec1_000379 CCN1C(=O)/C(=c\2/sc3nc4ccccc4n3c2=O)/c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B06 compound treatment 0.273 0.0469 6.48 0.286 0.0559 8.07 10.2922 0.9941 3210260 TimTec1_000380 CN(C)/C=C/c1cc-2c(cn1)C(=O)c3ccccc32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B07 compound treatment 0.247 0.0209 2.89 0.259 0.0289 4.17 4.9946 0.984 1780211 TimTec1_000381 CCN1CCc2c(C1)sc3[nH]c(=S)[nH]c(=S)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B08 compound treatment 0.231 0.00494 0.68 0.234 0.00388 0.56 0.8781 0.9952 3210261 TimTec1_000382 COC(=O)C1=NNC2(C)C1C(=O)N(C2=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B09 compound treatment 0.256 0.0299 4.14 0.254 0.0239 3.45 5.3631 0.9959 3081970 TimTec1_000383 CC1(C)CC(=O)N=C(Nc2ccc(Br)cc2)C(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B10 compound treatment 0.263 0.0369 5.1 0.265 0.0349 5.04 7.1704 1.0 3210262 TimTec1_000384 CCC1(NN(C(=S)N1)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B11 compound treatment 0.289 0.0629 8.69 0.272 0.0419 6.05 10.4253 0.9843 3210263 TimTec1_000385 CN(C)CCSc1nc(cc(c1C#N)c2ccc(Cl)cc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B12 compound treatment 0.322 0.0959 13.25 0.315 0.0849 12.26 18.0409 0.9992 1634534 TimTec1_000386 Cc1cccc(c1)C(=O)N(CCN2C(=O)c3ccccc3C2=O)c4cccc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B13 compound treatment 0.247 0.0209 2.89 0.259 0.0289 4.17 4.9946 0.984 1575191 TimTec1_000387 CCN(CC)S(=O)(=O)c1cc(ccc1C)c2nnc(o2)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B14 compound treatment 0.22 -0.00606 -0.84 0.228 -0.00212 -0.31 -0.8093 -0.9072 1606248 TimTec1_000388 CN(c1ccc(cc1)C(=O)N2CCCCC2)S(=O)(=O)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B15 compound treatment 0.224 -0.00206 -0.28 0.228 -0.00212 -0.31 -0.4185 -0.9993 3210264 TimTec1_000389 OC(=O)C(CC(=O)c1ccc(Br)cc1)NCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B16 compound treatment 0.243 0.0169 2.34 0.257 0.0269 3.88 4.3996 0.9706 1631485 TimTec1_000390 Brc1ccccc1OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B17 compound treatment 0.229 0.00294 0.41 0.233 0.00288 0.42 0.5806 0.9999 1246627 TimTec1_000391 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)n3ccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B18 compound treatment 0.225 -0.00106 -0.15 0.229 -0.00112 -0.16 -0.2187 -0.9987 1679013 TimTec1_000392 OC(=O)CCn1c(=O)n(CCC(=O)O)c2c(Cl)cc(Cl)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B19 compound treatment 0.418 0.192 26.52 0.406 0.176 25.4 36.7135 0.9998 3082038 TimTec1_000393 Oc1ccccc1/C=N/n2c(nc3ccccc3c2=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B20 compound treatment 0.224 -0.00206 -0.28 0.227 -0.00312 -0.45 -0.5207 -0.9754 1477092 TimTec1_000394 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc(F)cc2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B21 compound treatment 0.367 0.141 19.47 0.368 0.138 19.92 27.8502 0.9999 1663115 TimTec1_000395 CCOC(=O)c1c(C)[nH]c(=S)c(C#N)c1c2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B22 compound treatment 0.222 -0.00406 -0.56 0.228 -0.00212 -0.31 -0.6139 -0.9597 1283576 TimTec1_000396 CC(=O)Oc1ccccc1C(=O)N2CCN(CC2)c3cccc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B23 mock treatment 0.227 9.38E-4 0.13 0.235 0.00487 0.7 0.5895 0.8234 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 B24 positive control 0.226 -6.25E-5 -0.01 0.232 0.00188 0.27 0.1854 0.6842 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C01 compound treatment 0.242 0.0159 2.2 0.24 0.00987 1.43 2.5655 0.9779 1380400 TimTec1_000397 O=C(Nc1sc2CCCCCc2c1C(=O)N3CCOCC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C02 compound treatment 0.245 0.0189 2.62 0.253 0.0229 3.3 4.1864 0.9933 1651805 TimTec1_000398 CC(C(Cc1cc(C)cc(C)c1)c2nc3ccccc3[nH]2)c4nc5ccccc5[nH]4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C03 compound treatment 0.226 -6.25E-5 -0.01 0.223 -0.00712 -1.03 -0.7338 -0.713 1188845 TimTec1_000399 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C04 compound treatment 0.264 0.0379 5.24 0.272 0.0419 6.05 7.9831 0.9975 1525346 TimTec1_000400 NC(=O)c1c(NC(=O)C2CC2)sc3CCCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C05 compound treatment 0.218 -0.00806 -1.11 0.225 -0.00512 -0.74 -1.3111 -0.9803 3210265 TimTec1_000401 CC1=NN(C(=O)C1/C=N/C2CCS(=O)(=O)C2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C06 compound treatment 0.25 0.0239 3.31 0.244 0.0139 2.0 3.7556 0.9712 1333714 TimTec1_000402 O=C(NC1CCCC1)C(Sc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C07 compound treatment 0.236 0.00994 1.37 0.231 8.75E-4 0.13 1.0601 0.769 1642658 TimTec1_000403 O=C(COCC(=O)c1ccccc1)Sc2nc3ccccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C08 compound treatment 0.24 0.0139 1.93 0.237 0.00687 0.99 2.0637 0.9526 1608693 TimTec1_000404 CCN(CC)C(=O)c1sc(N)c(C#N)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C09 compound treatment 0.227 9.38E-4 0.13 0.229 -0.00112 -0.16 -0.0233 -0.1122 1606859 TimTec1_000405 COc1ccc(cc1)c2nn(C)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C10 compound treatment 0.26 0.0339 4.69 0.255 0.0249 3.59 5.856 0.9914 3082046 TimTec1_000406 COC(=O)c1csc(C(=O)OC)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C11 compound treatment 0.224 -0.00206 -0.28 0.224 -0.00612 -0.88 -0.8271 -0.8898 3210382 TimTec1_000407 CC(=O)Oc1ccccc1OCc2nn(C)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C12 compound treatment 0.269 0.0429 5.93 0.283 0.0529 7.64 9.595 0.9922 1715694 TimTec1_000408 CCOc1ccc(Oc2cc(NC(=O)c3ccc(F)cc3)cc(NC(=O)c4ccc(F)cc4)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C13 compound treatment 0.229 0.00294 0.41 0.228 -0.00212 -0.31 0.0699 0.1374 3082048 TimTec1_000409 O=C(CCN1CCOCC1)N/C=N\c2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C14 compound treatment 0.285 0.0589 8.14 0.281 0.0509 7.35 10.9538 0.9987 1388427 TimTec1_000410 COc1ccc(cc1)c2ccc(o2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C15 compound treatment 0.222 -0.00406 -0.56 0.217 -0.0131 -1.9 -1.7374 -0.8787 1724239 TimTec1_000411 O=C(CCc1ccccc1)NCCN2CCN(CC2)C(=O)CCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C16 compound treatment 0.228 0.00194 0.27 0.231 8.75E-4 0.13 0.2786 0.9413 3082050 TimTec1_000412 COC(=O)NCCOc1ccc(C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C17 compound treatment 0.293 0.0669 9.25 0.271 0.0409 5.9 10.7139 0.9765 1126232 TimTec1_000413 O=C(NCCC(c1ccccc1)c2ccccc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C18 compound treatment 0.292 0.0659 9.11 0.289 0.0589 8.5 12.4547 0.9994 1230497 TimTec1_000414 O=C(NCc1cccc2ccccc12)c3ccc4CCc5cccc3c54 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C19 compound treatment 0.229 0.00294 0.41 0.225 -0.00512 -0.74 -0.2365 -0.2801 1531449 TimTec1_000415 COc1ccccc1C(=O)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C20 compound treatment 0.228 0.00194 0.27 0.227 -0.00312 -0.45 -0.1299 -0.2476 1369763 TimTec1_000416 O=S(=O)(NCc1cccc2ccccc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C21 compound treatment 0.226 -6.25E-5 -0.01 0.225 -0.00512 -0.74 -0.5296 -0.7153 1183479 TimTec1_000417 C(Oc1cccc2cccnc12)C3CCCN4CCCCC34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C22 compound treatment 0.222 -0.00406 -0.56 0.224 -0.00612 -0.88 -1.0225 -0.9759 3081139 TimTec1_000418 Cc1nnc(SC(c2ccccc2)c3ccccc3)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C23 mock treatment 0.227 9.38E-4 0.13 0.233 0.00288 0.42 0.3852 0.8856 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 C24 positive control 0.229 0.00294 0.41 0.235 0.00487 0.7 0.7849 0.9657 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D01 compound treatment 0.278 0.0519 7.18 0.261 0.0309 4.46 8.2272 0.9738 1140783 TimTec1_000419 O=C(CSCC(=O)c1ccc(cc1)c2ccccc2)Nc3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D02 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 1615836 TimTec1_000420 NS(=O)(=O)c1ccc(CNC(=O)c2ccc(cc2)C(=O)N(C3CCCCC3)C4CCCCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D03 compound treatment 0.232 0.00594 0.82 0.229 -0.00112 -0.16 0.4651 0.5562 3081141 TimTec1_000421 Nc1nonc1/C(=N/O)/N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D04 compound treatment 0.226 -6.25E-5 -0.01 0.22 -0.0101 -1.46 -1.0403 -0.7113 1613632 TimTec1_000422 COC(=O)C1CCN(CC1)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D05 compound treatment 0.23 0.00394 0.54 0.232 0.00188 0.27 0.5762 0.9481 3081143 TimTec1_000423 COCCN1C(=O)/C(=C/c2sccc2C)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D06 compound treatment 0.223 -0.00306 -0.42 0.225 -0.00512 -0.74 -0.8226 -0.9648 1480512 TimTec1_000424 CCOC(=O)c1[nH]c(=O)[nH]c1Cn2nc(C)cc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D07 compound treatment 0.295 0.0689 9.52 0.294 0.0639 9.23 13.2584 0.9999 3210383 TimTec1_000425 Cc1ccc(/C=C/C(=O)Nc2sc3CCCCc3c2C#N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D08 compound treatment 0.421 0.195 26.93 0.43 0.2 28.87 39.4579 0.9994 1098479 TimTec1_000426 CCOC(=O)C1=NN(CC1C(=O)OC)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D09 compound treatment 0.275 0.0489 6.76 0.277 0.0469 6.77 9.5683 1.0 3210384 TimTec1_000427 CC(=O)N/C(=N\C(=O)C)/c1ccc(cc1)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D10 compound treatment 0.222 -0.00406 -0.56 0.221 -0.00912 -1.32 -1.3289 -0.9276 1312411 TimTec1_000428 CC1(C)Cc2ccccc2C(=N1)C(Cc3ccccc3)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D11 compound treatment 0.309 0.0829 11.46 0.316 0.0859 12.4 16.8731 0.9992 1238734 TimTec1_000429 Cn1c2CCCC(=O)c2c3cc(ccc13)C4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D12 compound treatment 0.226 -6.25E-5 -0.01 0.227 -0.00312 -0.45 -0.3253 -0.7205 1207720 TimTec1_000430 O=C1CCC(=O)N1c2ccccc2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D13 compound treatment 0.355 0.129 17.81 0.356 0.126 18.18 25.4523 0.9999 3210385 TimTec1_000431 COc1ccc(cc1)c2cc(nc(SC/C(=N\C#N)/N)c2C#N)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D14 compound treatment 0.256 0.0299 4.14 0.249 0.0189 2.73 4.8524 0.9796 3081150 TimTec1_000432 O=S(=O)(/N=c\1/cc(ss1)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D15 compound treatment 0.217 -0.00906 -1.25 0.213 -0.0171 -2.47 -2.6344 -0.9502 3210386 TimTec1_000433 CCN(CC)CCCNc1nc(Cl)nc(Nc2ccc(F)cc2F)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D16 compound treatment 0.223 -0.00306 -0.42 0.222 -0.00812 -1.17 -1.129 -0.905 1665252 TimTec1_000434 CCN(CC)C(=O)COCC1CCCN2CCCCC12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D17 compound treatment 0.225 -0.00106 -0.15 0.222 -0.00812 -1.17 -0.9337 -0.7894 3081152 TimTec1_000435 Clc1cc(Cl)cc(NC(=N)N2CCN(Cc3ccccc3)CC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D18 compound treatment 0.229 0.00294 0.41 0.228 -0.00212 -0.31 0.0699 0.1374 3210387 TimTec1_000436 CCOC(=O)c1c(C)n[nH]c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D19 compound treatment 0.245 0.0189 2.62 0.244 0.0139 2.0 3.2671 0.9913 3081154 TimTec1_000437 O=C(/C=C/c1ccccc1)C2CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D20 compound treatment 0.223 -0.00306 -0.42 0.222 -0.00812 -1.17 -1.129 -0.905 1277973 TimTec1_000438 CCC(C)NC(=O)c1ccc(OC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D21 compound treatment 0.291 0.0649 8.97 0.288 0.0579 8.36 12.2549 0.9994 1511267 TimTec1_000439 COc1ccc(OCc2c(C#N)c3ccccc3n2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D22 compound treatment 0.232 0.00594 0.82 0.234 0.00388 0.56 0.9758 0.9826 1736813 TimTec1_000440 CC(NC(=O)c1ccccc1OC(=O)C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D23 mock treatment 0.229 0.00294 0.41 0.23 -1.25E-4 -0.02 0.2742 0.675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 D24 positive control 0.229 0.00294 0.41 0.233 0.00288 0.42 0.5806 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E01 compound treatment 0.234 0.00794 1.1 0.24 0.00987 1.43 1.784 0.9916 1576550 TimTec1_000441 Brc1ccc(cc1)S(=O)(=O)N2CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E02 compound treatment 0.247 0.0209 2.89 0.255 0.0249 3.59 4.586 0.9942 1538091 TimTec1_000442 CCOc1ccc(NC(=O)CC(C)Cc2cc(C)cc(C)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E03 compound treatment 0.419 0.193 26.65 0.448 0.218 31.47 41.101 0.9966 1380584 TimTec1_000443 Cc1ccc(o1)c2cc(C(=O)O)c3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E04 compound treatment 0.22 -0.00606 -0.84 0.224 -0.00612 -0.88 -1.2178 -0.9996 1384234 TimTec1_000444 Cc1onc(c1C(=O)NCc2ccc(F)cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E05 compound treatment 0.415 0.189 26.1 0.348 0.118 17.03 30.4964 0.9786 3210388 TimTec1_000445 Cc1nn(c(O)c1/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E06 compound treatment 0.22 -0.00606 -0.84 0.228 -0.00212 -0.31 -0.8093 -0.9072 1727240 TimTec1_000446 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3CCCO3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E07 compound treatment 0.242 0.0159 2.2 0.264 0.0339 4.89 5.0168 0.935 1282347 TimTec1_000447 O=C(COCC(=O)c1ccccc1)Sc2nc3ccccc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E08 compound treatment 0.23 0.00394 0.54 0.229 -0.00112 -0.16 0.2697 0.4751 1626029 TimTec1_000448 CC(NC(=O)c1ccccc1)C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E09 compound treatment 0.226 -6.25E-5 -0.01 0.228 -0.00212 -0.31 -0.2231 -0.7267 3081750 TimTec1_000449 Cc1ccc(OCc2nn(C)c3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E10 compound treatment 0.225 -0.00106 -0.15 0.223 -0.00712 -1.03 -0.8315 -0.7999 3081752 TimTec1_000450 Cn1ncc(Br)c1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E11 compound treatment 0.221 -0.00506 -0.7 0.215 -0.0151 -2.18 -2.0394 -0.889 1483987 TimTec1_000451 O=C(Cc1nc2ccccc2[nH]1)Oc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E12 compound treatment 0.241 0.0149 2.06 0.249 0.0189 2.73 3.3871 0.9906 1161165 TimTec1_000452 OC(=O)c1cc2cccc(c2cc1O)S(=O)(=O)NCC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E13 compound treatment 0.224 -0.00206 -0.28 0.226 -0.00412 -0.6 -0.6228 -0.943 3081755 TimTec1_000453 O=C(N/C=N\c1cccnc1)C2COc3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E14 compound treatment 0.221 -0.00506 -0.7 0.218 -0.0121 -1.75 -1.733 -0.9189 1290467 TimTec1_000454 CCCc1nc(c(NC)o1)S(=O)(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E15 compound treatment 0.241 0.0149 2.06 0.249 0.0189 2.73 3.3871 0.9906 1210563 TimTec1_000455 Cc1cc(C)c(c(C)c1)n2cccc2CN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E16 compound treatment 0.238 0.0119 1.65 0.224 -0.00612 -0.88 0.5405 0.2888 1600581 TimTec1_000456 O=C(NCc1ccc2OCOc2c1)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E17 compound treatment 0.247 0.0209 2.89 0.248 0.0179 2.58 3.8711 0.9984 3210389 TimTec1_000457 Clc1ccccc1c2ccc(/C=C/3\SC(=S)N(CC4CCCO4)C3=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E18 compound treatment 0.341 0.115 15.88 0.321 0.0909 13.13 20.5098 0.9955 1166878 TimTec1_000458 O=C(NCc1cccc2ccccc12)C(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E19 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 1409245 TimTec1_000459 Clc1ccc(OCC(=O)OCC2CCCN3CCCCC23)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E20 compound treatment 0.229 0.00294 0.41 0.227 -0.00312 -0.45 -0.0322 -0.0531 1120094 TimTec1_000460 Cc1ccc(CSc2nnc(N)s2)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E21 compound treatment 0.223 -0.00306 -0.42 0.22 -0.0101 -1.46 -1.3333 -0.8758 1262423 TimTec1_000461 O=C1CCC(=O)N1OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E22 compound treatment 0.218 -0.00806 -1.11 0.223 -0.00712 -1.03 -1.5153 -0.9992 3210390 TimTec1_000462 COc1ccc(cc1)c2nnc(SCC(=O)CSc3nnc([nH]3)c4ccc(OC)cc4)[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E23 mock treatment 0.225 -0.00106 -0.15 0.23 -1.25E-4 -0.02 -0.1166 -0.7881 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 E24 positive control 0.228 0.00194 0.27 0.234 0.00388 0.56 0.5851 0.943 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F01 compound treatment 0.222 -0.00406 -0.56 0.221 -0.00912 -1.32 -1.3289 -0.9276 3081761 TimTec1_000463 C(Sc1nnc(c2ccco2)n1c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F02 compound treatment 0.215 -0.0111 -1.53 0.222 -0.00812 -1.17 -1.9105 -0.9915 1189560 TimTec1_000464 O=C(NCCc1c[nH]c2ccccc12)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F03 compound treatment 0.27 0.0439 6.07 0.282 0.0519 7.49 9.5906 0.9945 3210512 TimTec1_000465 COc1ccc(cc1COc2cccc(Cl)c2)C3C4C(NN=C4C)OC(=C3C#N)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F04 compound treatment 0.222 -0.00406 -0.56 0.223 -0.00712 -1.03 -1.1246 -0.9593 3081764 TimTec1_000466 O=c1/c(=C/c2ccc(cc2)N3CCOCC3)/sc4nc5ccccc5n14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F05 compound treatment 0.238 0.0119 1.65 0.246 0.0159 2.29 2.7876 0.9869 1511275 TimTec1_000467 CCOC(=O)C1=C(NC(=O)c2cccs2)C(CC=C)C(=S)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F06 compound treatment 0.235 0.00894 1.23 0.241 0.0109 1.57 1.9838 0.9929 1440881 TimTec1_000468 O=C(CNS(=O)(=O)c1ccccc1)Oc2ccc3ccc(=O)oc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F07 compound treatment 0.23 0.00394 0.54 0.236 0.00587 0.85 0.9847 0.9769 3210513 TimTec1_000469 Cc1c(NC(=O)/C=C/c2ccc(Cl)cc2Cl)c(=O)n(c3ccccc3)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F08 compound treatment 0.252 0.0259 3.58 0.25 0.0199 2.87 4.5638 0.994 1518488 TimTec1_000470 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F09 compound treatment 0.261 0.0349 4.83 0.271 0.0409 5.9 7.5879 0.995 1338448 TimTec1_000471 O=C(CCc1ccccc1)Nc2cccc(NC(=O)CCc3ccccc3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F10 compound treatment 0.259 0.0329 4.55 0.248 0.0179 2.58 5.0433 0.964 1388176 TimTec1_000472 O=C(N1CCCCC1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F11 compound treatment 0.301 0.0749 10.35 0.311 0.0809 11.68 15.5809 0.9982 1550208 TimTec1_000473 Nc1nc(N)c2sc(Nc3ccccc3)c(C#N)c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F12 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 1706746 TimTec1_000474 O=C(NCc1ccco1)c2ccccc2C(=O)c3ncc[nH]3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F13 compound treatment 0.262 0.0359 4.96 0.266 0.0359 5.18 7.1749 0.9998 1726053 TimTec1_000475 NC(=O)c1c(SCC#N)nc(cc1c2ccc(F)cc2)C3CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F14 compound treatment 0.224 -0.00206 -0.28 0.219 -0.0111 -1.61 -1.3378 -0.8197 3081820 TimTec1_000476 COC1(OC)N=C(N)C2(C#N)C3CCC(C=C3)C12C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F15 compound treatment 0.303 0.0769 10.63 0.293 0.0629 9.08 13.9378 0.9969 1570113 TimTec1_000477 CNC(=S)N(Cc1ccc(OC)cc1OC)c2ccc(cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F16 compound treatment 0.222 -0.00406 -0.56 0.222 -0.00812 -1.17 -1.2267 -0.943 1573637 TimTec1_000478 C[N+]12CCCCC2C(COC(=O)c3ccccn3)CCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F17 compound treatment 0.228 0.00194 0.27 0.225 -0.00512 -0.74 -0.3342 -0.4245 3210514 TimTec1_000479 Cc1ccc(cc1)C(=O)CC(NCCN2CCOCC2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F18 compound treatment 0.237 0.0109 1.51 0.23 -1.25E-4 -0.02 1.0557 0.6986 2120076 TimTec1_000480 Cl/C(=N\c1ccccc1)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F19 compound treatment 0.22 -0.00606 -0.84 0.226 -0.00412 -0.6 -1.0136 -0.9861 3081824 TimTec1_000481 CCN(CC)C(=O)c1ccc[n+](CC(=O)N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F20 compound treatment 0.219 -0.00706 -0.98 0.22 -0.0101 -1.46 -1.7241 -0.9806 1381433 TimTec1_000482 CC(=O)Nc1ccc(cc1)C(=O)N(CC#N)CC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F21 compound treatment 0.244 0.0179 2.48 0.239 0.00887 1.28 2.6588 0.9529 1233063 TimTec1_000483 Cc1cc(=O)oc2ccc(OCC(=O)N3CCOCC3)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F22 compound treatment 0.229 0.00294 0.41 0.228 -0.00212 -0.31 0.0699 0.1374 1243176 TimTec1_000484 CC(=O)Oc1ccccc1C(=O)NC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F23 mock treatment 0.224 -0.00206 -0.28 0.23 -1.25E-4 -0.02 -0.2142 -0.7504 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 F24 positive control 0.228 0.00194 0.27 0.233 0.00288 0.42 0.4829 0.9774 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G01 compound treatment 0.231 0.00494 0.68 0.243 0.0129 1.86 1.7974 0.9074 1705462 TimTec1_000485 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4cccc(Cl)c4Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G02 compound treatment 0.221 -0.00506 -0.7 0.222 -0.00812 -1.17 -1.3244 -0.9694 1202595 TimTec1_000486 Cc1cc(C)cc(CC(CC(=O)O)C(=O)NCc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G03 compound treatment 0.232 0.00594 0.82 0.229 -0.00112 -0.16 0.4651 0.5562 1578135 TimTec1_000487 COc1ccc(OC)c(NC(=O)c2cccnc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G04 compound treatment 0.234 0.00794 1.1 0.235 0.00487 0.7 1.2733 0.9771 3081828 TimTec1_000488 FC(F)(F)c1ccccc1NC(=O)c2cnccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G05 compound treatment 0.223 -0.00306 -0.42 0.223 -0.00712 -1.03 -1.0269 -0.9229 3210515 TimTec1_000489 CCOC(=O)C1(NC(=S)N2CCOCC2)Sc3cc(C)ccc3NC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G06 compound treatment 0.355 0.129 17.81 0.35 0.12 17.32 24.8394 0.9999 1293037 TimTec1_000490 COc1ccc(NC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G07 compound treatment 0.229 0.00294 0.41 0.229 -0.00112 -0.16 0.1721 0.3936 3210516 TimTec1_000491 O=C(Cc1ccccc1)Sc2ncn[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G08 compound treatment 0.261 0.0349 4.83 0.264 0.0339 4.89 6.8729 1.0 3210517 TimTec1_000492 CCOC(=O)c1cnn2c(cc(nc12)c3ccc(OC)cc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G09 compound treatment 0.218 -0.00806 -1.11 0.22 -0.0101 -1.46 -1.8218 -0.991 3081831 TimTec1_000493 Oc1ccc(Cn2nc(c3ccc(O)cc3)c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G10 compound treatment 0.249 0.0229 3.17 0.249 0.0189 2.73 4.1686 0.9972 1071560 TimTec1_000494 CCOC(=O)c1sc(N)c(C(=O)OCC)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G11 compound treatment 0.218 -0.00806 -1.11 0.219 -0.0111 -1.61 -1.9239 -0.984 3210518 TimTec1_000495 Cn1nc(c2ccc(Cl)cc2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G12 compound treatment 0.225 -0.00106 -0.15 0.225 -0.00512 -0.74 -0.6273 -0.8311 1169828 TimTec1_000496 Cn1nc(cc1C(=O)N2CCOCC2)C(=O)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G13 compound treatment 0.234 0.00794 1.1 0.236 0.00587 0.85 1.3755 0.992 1636675 TimTec1_000497 O=C(Sc1cccc2ncccc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G14 compound treatment 0.219 -0.00706 -0.98 0.218 -0.0121 -1.75 -1.9283 -0.9618 1539302 TimTec1_000498 CCCc1ccc(OCC(O)CN2CC(C)OC(C)C2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G15 compound treatment 0.22 -0.00606 -0.84 0.218 -0.0121 -1.75 -1.8307 -0.943 1391849 TimTec1_000499 Fc1ccccc1C(=O)NC2CCC(CC2)NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G16 compound treatment 0.224 -0.00206 -0.28 0.224 -0.00612 -0.88 -0.8271 -0.8898 3210519 TimTec1_000500 COc1ccccc1OCCNC(=O)c2ccc3CCc4cccc2c43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G17 compound treatment 0.272 0.0459 6.35 0.267 0.0369 5.33 8.2539 0.9962 3081837 TimTec1_000501 COCCN1C(=O)/C(=C\2/C(=O)N(OC)c3ccccc23)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G18 compound treatment 0.266 0.0399 5.52 0.272 0.0419 6.05 8.1784 0.9989 1286375 TimTec1_000502 O=C(NCc1cccc2ccccc12)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G19 compound treatment 0.222 -0.00406 -0.56 0.224 -0.00612 -0.88 -1.0225 -0.9759 1364575 TimTec1_000503 NCCC(=O)OCC1CCCN2CCCCC12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G20 compound treatment 0.254 0.0279 3.86 0.237 0.00687 0.99 3.4314 0.861 3081904 TimTec1_000504 Cc1ccc(CSc2nc3ccccc3s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G21 compound treatment 0.271 0.0449 6.21 0.275 0.0449 6.48 8.9733 0.9998 1216012 TimTec1_000505 O=C(COCC1CCCN2CCCCC12)Oc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G22 compound treatment 0.252 0.0259 3.58 0.241 0.0109 1.57 3.6445 0.9315 1654975 TimTec1_000506 O=C(CSCC(=O)c1ccc-2c(Cc3ccccc32)c1)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G23 mock treatment 0.227 9.38E-4 0.13 0.229 -0.00112 -0.16 -0.0233 -0.1122 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 G24 positive control 0.225 -0.00106 -0.15 0.232 0.00188 0.27 0.0877 0.2847 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H01 compound treatment 0.402 0.176 24.31 0.434 0.204 29.45 38.0104 0.9955 3081906 TimTec1_000507 C(Sc1nc2ccccc2s1)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H02 compound treatment 0.275 0.0489 6.76 0.281 0.0509 7.35 9.9769 0.9991 1631930 TimTec1_000508 COc1ccc(cc1OC)c2nnc(o2)c3ccc(cc3)S(=O)(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H03 compound treatment 0.397 0.171 23.62 0.4 0.17 24.54 34.0492 0.9998 1266410 TimTec1_000509 NC1=C(C#N)C(C(=C(N)S1)C#N)c2ccncc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H04 compound treatment 0.251 0.0249 3.45 0.261 0.0309 4.46 5.5896 0.9919 1442167 TimTec1_000510 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCc2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H05 compound treatment 0.254 0.0279 3.86 0.255 0.0249 3.59 5.2698 0.9994 3210520 TimTec1_000511 Clc1ccc(c2ccc(/C=C(\NC(=O)c3ccccc3)/C(=O)N4CCCC4)o2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H06 compound treatment 0.265 0.0389 5.38 0.251 0.0209 3.02 5.9359 0.9626 1738071 TimTec1_000512 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)c4nc5cc(Cl)ccc5c(=O)o4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H07 compound treatment 0.228 0.00194 0.27 0.223 -0.00712 -1.03 -0.5385 -0.5064 1329849 TimTec1_000513 O=C(Nc1ccc(Oc2ccccc2)cc1)C3CCCO3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H08 compound treatment 0.232 0.00594 0.82 0.241 0.0109 1.57 1.6908 0.9541 1630279 TimTec1_000514 C(N1CCN(Cc2ccccc2)C1c3ccc4OCOc4c3)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H09 compound treatment 0.403 0.177 24.44 0.42 0.19 27.43 36.6781 0.9984 1681726 TimTec1_000515 NC(=O)C1C(C(=C(N)NC1=S)C#N)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H10 compound treatment 0.22 -0.00606 -0.84 0.22 -0.0101 -1.46 -1.6264 -0.965 1578391 TimTec1_000516 CC(=O)OC1(CC(CN(C1)C(C)(C)C)C(C)(C)C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H11 compound treatment 0.248 0.0219 3.03 0.243 0.0129 1.86 3.4581 0.9725 1698115 TimTec1_000517 Brc1ccc(Nc2nc(cs2)c3ccc(cc3)S(=O)(=O)N4CCCCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H12 compound treatment 0.296 0.0699 9.66 0.318 0.0879 12.69 15.8074 0.9909 1204133 TimTec1_000518 O=S(=O)(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H13 compound treatment 0.248 0.0219 3.03 0.254 0.0239 3.45 4.5816 0.9979 1427336 TimTec1_000519 CC(C)N1CCC2(CC1)C(=C(N)NC(=C2C#N)S)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H14 compound treatment 0.223 -0.00306 -0.42 0.224 -0.00612 -0.88 -0.9248 -0.943 1552647 TimTec1_000520 Cn1c(CN2CCCCC2)c(C#N)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H15 compound treatment 0.305 0.0789 10.91 0.309 0.0789 11.39 15.7674 0.9998 1575250 TimTec1_000521 COc1cccc(CN(C(=S)NCc2ccccc2)c3ccc(F)c(Cl)c3)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H16 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 1570436 TimTec1_000522 Oc1ccccc1C(=O)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H17 compound treatment 0.23 0.00394 0.54 0.225 -0.00512 -0.74 -0.1388 -0.1511 3210637 TimTec1_000523 OC(=O)C(CC(=O)c1ccc(Br)cc1)NCCc2cc3ccccc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H18 compound treatment 0.226 -6.25E-5 -0.01 0.225 -0.00512 -0.74 -0.5296 -0.7153 1321027 TimTec1_000524 CCc1cccc(C)c1NC(=O)c2ccc(OC(=O)C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H19 compound treatment 0.269 0.0429 5.93 0.273 0.0429 6.19 8.5736 0.9998 1312477 TimTec1_000525 CC1=C(C(C(=C(S)N1)C#N)c2ccncc2)C(=O)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H20 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 1393948 TimTec1_000526 CCCNC(=O)c1ccc(NC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H21 compound treatment 0.224 -0.00206 -0.28 0.222 -0.00812 -1.17 -1.0314 -0.854 1298760 TimTec1_000527 O=C(NCc1ccc2OCOc2c1)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H22 compound treatment 0.223 -0.00306 -0.42 0.223 -0.00712 -1.03 -1.0269 -0.9229 1374460 TimTec1_000528 CC(=O)Oc1ccccc1C(=O)N2CCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H23 mock treatment 0.229 0.00294 0.41 0.228 -0.00212 -0.31 0.0699 0.1374 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 H24 positive control 0.224 -0.00206 -0.28 0.234 0.00388 0.56 0.1943 0.3094 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I01 compound treatment 0.354 0.128 17.67 0.354 0.124 17.89 25.1503 1.0 1566570 TimTec1_000529 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I02 compound treatment 0.219 -0.00706 -0.98 0.222 -0.00812 -1.17 -1.5198 -0.9958 1193846 TimTec1_000530 OC(=O)CCc1cn(CCC(=O)O)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I03 compound treatment 0.223 -0.00306 -0.42 0.25 0.0199 2.87 1.7308 0.5965 1083948 TimTec1_000531 Clc1ccc(NC(=O)Cc2ccccc2)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I04 compound treatment 0.217 -0.00906 -1.25 0.221 -0.00912 -1.32 -1.8173 -0.9997 1450798 TimTec1_000532 CCOc1ccccc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I05 compound treatment 0.235 0.00894 1.23 0.238 0.00787 1.14 1.6774 0.9992 3210638 TimTec1_000533 CCOC(=O)c1c(NC(=O)CN2C(=O)S/C(=C/c3ccc(F)cc3)/C2=O)sc4CCCCc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I06 compound treatment 0.293 0.0669 9.25 0.293 0.0629 9.08 12.9609 1.0 1441802 TimTec1_000534 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccccc4)C(=O)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I07 compound treatment 0.259 0.0329 4.55 0.264 0.0339 4.89 6.6775 0.9993 3210639 TimTec1_000535 COc1ccc(CC(=O)Sc2nc3ccccc3s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I08 compound treatment 0.315 0.0889 12.29 0.289 0.0589 8.5 14.7015 0.9838 1043205 TimTec1_000536 COc1ccc2Sc3ccccc3Nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I09 compound treatment 0.272 0.0459 6.35 0.259 0.0289 4.17 7.4368 0.9793 1647938 TimTec1_000537 O=C(c1ccccc1)c2ccccc2OCc3nc4ccccc4s3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I10 compound treatment 0.255 0.0289 4.0 0.263 0.0329 4.75 6.1846 0.9963 1583677 TimTec1_000538 COC(=O)c1c(N)sc2CC(CCc12)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I11 compound treatment 0.22 -0.00606 -0.84 0.219 -0.0111 -1.61 -1.7285 -0.9539 3210640 TimTec1_000539 OC(=O)c1ccccc1OCC(=O)N2CCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I12 compound treatment 0.243 0.0169 2.34 0.239 0.00887 1.28 2.5611 0.9599 3081983 TimTec1_000540 Fc1ccc(CC(=O)Oc2ccccc2F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I13 compound treatment 0.249 0.0229 3.17 0.245 0.0149 2.15 3.76 0.9821 1530773 TimTec1_000541 Clc1c(sc2ccccc12)C(=O)NC3CC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I14 compound treatment 0.264 0.0379 5.24 0.274 0.0439 6.34 8.1873 0.9955 1155672 TimTec1_000542 O=C(N(C1CCCC1)C2CCCC2)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I15 compound treatment 0.226 -6.25E-5 -0.01 0.225 -0.00512 -0.74 -0.5296 -0.7153 1319420 TimTec1_000543 Cc1cc2OCCn2c(=O)c1C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I16 compound treatment 0.235 0.00894 1.23 0.23 -1.25E-4 -0.02 0.8603 0.6967 3210641 TimTec1_000544 CC(C)c1ccc(C)cc1OCCNC(=O)Nc2ccc(Br)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I17 compound treatment 0.359 0.133 18.37 0.366 0.136 19.63 26.8644 0.9994 3081987 TimTec1_000545 Cc1cccc(c1)N2CCC(=N2)/N=C/N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I18 compound treatment 0.222 -0.00406 -0.56 0.226 -0.00412 -0.6 -0.8182 -0.9996 1266605 TimTec1_000546 O=C(NCc1ccc2OCOc2c1)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I19 compound treatment 0.225 -0.00106 -0.15 0.221 -0.00912 -1.32 -1.0358 -0.781 1545215 TimTec1_000547 O=C(CCN1C(=O)CCC1=O)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I20 compound treatment 0.221 -0.00506 -0.7 0.223 -0.00712 -1.03 -1.2223 -0.9823 3210642 TimTec1_000548 CC(Sc1nnnn1c2ccccc2)C(=O)Nc3c(C)cc(C)cc3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I21 compound treatment 0.222 -0.00406 -0.56 0.224 -0.00612 -0.88 -1.0225 -0.9759 1121440 TimTec1_000549 OCCN1CC2CC(C1)c3cccc(=O)n3C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I22 compound treatment 0.248 0.0219 3.03 0.254 0.0239 3.45 4.5816 0.9979 1565244 TimTec1_000550 O=C(CSC(c1ccccc1)c2ccccc2)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I23 mock treatment 0.227 9.38E-4 0.13 0.232 0.00188 0.27 0.2831 0.943 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 I24 positive control 0.222 -0.00406 -0.56 0.233 0.00288 0.42 -0.1032 -0.1478 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J01 compound treatment 0.3 0.0739 10.21 0.318 0.0879 12.69 16.1982 0.9942 3081991 TimTec1_000551 C(Sc1nc2ccccc2o1)c3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J02 compound treatment 0.246 0.0199 2.75 0.254 0.0239 3.45 4.3862 0.9938 1373763 TimTec1_000552 CCOc1cc(ccc1OC)C(=S)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J03 compound treatment 0.373 0.147 20.3 0.377 0.147 21.22 29.3556 0.9998 1655707 TimTec1_000553 CCOC(=O)c1cccc(c1)c2ccc(o2)C3C4C(OC(=C3C#N)N)c5ccccc5OC4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J04 compound treatment 0.251 0.0249 3.45 0.252 0.0219 3.16 4.6704 0.9991 3210643 TimTec1_000554 Cc1nc2ccccc2c(=O)n1/N=C/c3ccsc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J05 compound treatment 0.229 0.00294 0.41 0.233 0.00288 0.42 0.5806 0.9999 1122674 TimTec1_000555 CCOC(=O)C1=C(NC(=S)NC1C)C2CCC=CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J06 compound treatment 0.232 0.00594 0.82 0.26 0.0299 4.32 3.6314 0.8267 1230190 TimTec1_000556 CC(=O)Oc1ccc2nc(CN3C(=O)c4ccccc4C3=O)oc(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J07 compound treatment 0.292 0.0659 9.11 0.295 0.0649 9.37 13.0675 0.9999 1236736 TimTec1_000557 O=C(Oc1ccccc1)[C@@H]2[C@@H](c3ccoc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J08 compound treatment 0.231 0.00494 0.68 0.225 -0.00512 -0.74 -0.0411 -0.0409 1297872 TimTec1_000558 CC(C)OC(=O)Oc1ccc2oc(=O)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J09 compound treatment 0.267 0.0409 5.66 0.276 0.0459 6.63 8.6847 0.9969 1481447 TimTec1_000559 CC(O)(C#Cc1ccccc1)c2ccc(N3CCCCC3)c(F)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J10 compound treatment 0.233 0.00694 0.96 0.22 -0.0101 -1.46 -0.3564 -0.2038 1391128 TimTec1_000560 CC1(C)CC(=O)c2cc(c3ccccc3)n(c2C1)c4ccc(cc4)S(=O)(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J11 compound treatment 0.228 0.00194 0.27 0.227 -0.00312 -0.45 -0.1299 -0.2476 3210645 TimTec1_000561 FC(F)(F)c1cccc(NCn2nc(oc2=S)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J12 compound treatment 0.23 0.00394 0.54 0.222 -0.00812 -1.17 -0.4452 -0.3442 1726909 TimTec1_000562 Clc1ccc(cc1)C(=O)NCc2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J13 compound treatment 0.237 0.0109 1.51 0.231 8.75E-4 0.13 1.1578 0.7636 1416599 TimTec1_000563 NC1=C(C#N)C2=CCNCC2C(c3ccccc3)C1(C#N)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J14 compound treatment 0.315 0.0889 12.29 0.315 0.0849 12.26 17.3571 1.0 3210646 TimTec1_000564 CCCc1cc2c(=O)c(c3ccc4OCCOc4c3)c(oc2c(C=N(C)C)c1O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J15 compound treatment 0.239 0.0129 1.79 0.258 0.0279 4.03 4.1109 0.9332 1693767 TimTec1_000565 CNC(=S)N(Cc1ccc(OC)cc1OC)c2ccc(I)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J16 compound treatment 0.222 -0.00406 -0.56 0.225 -0.00512 -0.74 -0.9203 -0.9907 1775537 TimTec1_000566 Cc1ccccc1C(=O)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J17 compound treatment 0.248 0.0219 3.03 0.234 0.00388 0.56 2.5388 0.8238 3082061 TimTec1_000567 Cc1ccc(cc1)C(=O)CC(NCCc2c[nH]c3ccccc23)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J18 compound treatment 0.223 -0.00306 -0.42 0.227 -0.00312 -0.45 -0.6184 -0.9995 1438042 TimTec1_000568 CCN(C(=O)c1ccc(OC(=O)C)cc1)c2ccccc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J19 compound treatment 0.23 0.00394 0.54 0.231 8.75E-4 0.13 0.474 0.8488 1030998 TimTec1_000569 CCc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J20 compound treatment 0.225 -0.00106 -0.15 0.229 -0.00112 -0.16 -0.2187 -0.9987 2085724 TimTec1_000570 CCc1cccc(C)c1NC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J21 compound treatment 0.224 -0.00206 -0.28 0.222 -0.00812 -1.17 -1.0314 -0.854 1132592 TimTec1_000571 Clc1ccc(Cl)c(c1)S(=O)(=O)n2ccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J22 compound treatment 0.223 -0.00306 -0.42 0.224 -0.00612 -0.88 -0.9248 -0.943 1473958 TimTec1_000572 CC(=O)Oc1ccccc1C(=O)NCc2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J23 mock treatment 0.229 0.00294 0.41 0.232 0.00188 0.27 0.4785 0.9807 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 J24 positive control 0.228 0.00194 0.27 0.235 0.00487 0.7 0.6872 0.9122 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K01 compound treatment 0.24 0.0139 1.93 0.235 0.00487 0.7 1.8594 0.907 1711757 TimTec1_000573 Clc1c(sc2ccccc12)C(=O)N3CCc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K02 compound treatment 0.219 -0.00706 -0.98 0.226 -0.00412 -0.6 -1.1112 -0.972 3082065 TimTec1_000574 C(=N/c1nc2ccccc2[nH]1)\N(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K03 compound treatment 0.217 -0.00906 -1.25 0.222 -0.00812 -1.17 -1.7152 -0.9995 1572077 TimTec1_000575 O=C(NCCN1CCOCC1)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K04 compound treatment 0.226 -6.25E-5 -0.01 0.224 -0.00612 -0.88 -0.6317 -0.714 1453184 TimTec1_000576 CCC(C(=O)Nc1c(C)n(C)n(c2ccccc2)c1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K05 compound treatment 0.227 9.38E-4 0.13 0.227 -0.00312 -0.45 -0.2276 -0.4847 1610602 TimTec1_000577 Cc1cccc2nc(Cn3ccccc3=O)cn12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K06 compound treatment 0.232 0.00594 0.82 0.241 0.0109 1.57 1.6908 0.9541 3082068 TimTec1_000578 Clc1ccc(cc1Cl)C(=O)N2CCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K07 compound treatment 0.263 0.0369 5.1 0.285 0.0549 7.93 9.2132 0.9773 1335233 TimTec1_000579 COc1ccc(CC(=O)Sc2nc3ccccc3o2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K08 compound treatment 0.231 0.00494 0.68 0.231 8.75E-4 0.13 0.5717 0.8241 1575168 TimTec1_000580 COC(=O)c1ccc(CSc2nc3ccccc3s2)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K09 compound treatment 0.378 0.152 20.99 0.354 0.124 17.89 27.4948 0.9968 1544044 TimTec1_000581 Cc1c([nH]c2ccccc12)c3ccccc3OC(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K10 compound treatment 0.266 0.0399 5.52 0.268 0.0379 5.47 7.7699 1.0 1742152 TimTec1_000582 CC(C)(C)C1CCc2c(C#N)c(N)sc2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K11 compound treatment 0.224 -0.00206 -0.28 0.223 -0.00712 -1.03 -0.9292 -0.8701 1582197 TimTec1_000583 CC(C)COc1ccc(OCC(C)C)c(N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K12 compound treatment 0.224 -0.00206 -0.28 0.224 -0.00612 -0.88 -0.8271 -0.8898 3210777 TimTec1_000584 Cc1cccc(OC(=O)Cc2ccc(F)cc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K13 compound treatment 0.235 0.00894 1.23 0.228 -0.00212 -0.31 0.656 0.5156 1222918 TimTec1_000585 O=C(NC1CCC(CC2CCC(CC2)NC(=O)c3cccnc3)CC1)c4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K14 compound treatment 0.226 -6.25E-5 -0.01 0.229 -0.00112 -0.16 -0.121 -0.7436 1594065 TimTec1_000586 O=C(NCc1ccco1)C(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K15 compound treatment 0.242 0.0159 2.2 0.251 0.0209 3.02 3.689 0.9881 1561515 TimTec1_000587 CCOC(=O)c1cnc(nc1NCc2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K16 compound treatment 0.225 -0.00106 -0.15 0.226 -0.00412 -0.6 -0.5251 -0.8557 1376512 TimTec1_000588 O=C(CSCc1ccccc1)NCc2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K17 compound treatment 0.408 0.182 25.13 0.406 0.176 25.4 35.7366 1.0 3081162 TimTec1_000589 OCCN(CCO)/C=N/C1=NN(CC1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K18 compound treatment 0.222 -0.00406 -0.56 0.227 -0.00312 -0.45 -0.716 -0.9942 1454649 TimTec1_000590 Clc1ccc(CCNC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K19 compound treatment 0.222 -0.00406 -0.56 0.227 -0.00312 -0.45 -0.716 -0.9942 1521681 TimTec1_000591 O=C(CNC(=O)c1ccccc1)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K20 compound treatment 0.244 0.0179 2.48 0.239 0.00887 1.28 2.6588 0.9529 1335587 TimTec1_000592 O=C(CSc1cccc2cccnc12)NCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K21 compound treatment 0.229 0.00294 0.41 0.228 -0.00212 -0.31 0.0699 0.1374 1610318 TimTec1_000593 CC(O)CN1CCCCC1c2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K22 compound treatment 0.277 0.0509 7.04 0.272 0.0419 6.05 9.253 0.9972 1566510 TimTec1_000594 O=C(CSCC(=O)Nc1ccccc1Oc2ccccc2)Nc3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K23 mock treatment 0.229 0.00294 0.41 0.232 0.00188 0.27 0.4785 0.9807 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 K24 positive control 0.228 0.00194 0.27 0.232 0.00188 0.27 0.3808 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L01 compound treatment 0.263 0.0369 5.1 0.255 0.0249 3.59 6.149 0.9853 1594804 TimTec1_000595 O=C(CSc1nc(c[nH]1)c2ccccc2)c3ccc(cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L02 compound treatment 0.221 -0.00506 -0.7 0.222 -0.00812 -1.17 -1.3244 -0.9694 1439459 TimTec1_000596 CC(=C1C2C=CC1C3C2C(=O)N(Cc4cccnc4)C3=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L03 compound treatment 0.226 -6.25E-5 -0.01 0.227 -0.00312 -0.45 -0.3253 -0.7205 3081167 TimTec1_000597 Cc1[nH]nc(O)c1C(C(C#N)C#N)c2ccncc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L04 compound treatment 0.273 0.0469 6.48 0.272 0.0419 6.05 8.8623 0.9994 1273129 TimTec1_000598 CCc1[nH]c(=S)c(C#N)c(c2ccccc2)c1C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L05 compound treatment 0.229 0.00294 0.41 0.23 -1.25E-4 -0.02 0.2742 0.675 3081169 TimTec1_000599 CN1C(=O)/C(=C/2\SC(=S)N(CC3CCCO3)C2=O)/c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L06 compound treatment 0.225 -0.00106 -0.15 0.228 -0.00212 -0.31 -0.3208 -0.943 1050772 TimTec1_000600 COc1cccc(c1)c2nnc(o2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L07 compound treatment 0.249 0.0229 3.17 0.244 0.0139 2.0 3.6579 0.9756 3081170 TimTec1_000601 CN(C)c1ccc(cc1)c2oncc2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L08 compound treatment 0.234 0.00794 1.1 0.226 -0.00412 -0.6 0.3541 0.2837 1311113 TimTec1_000602 O=C(N1CCCCC1)c2cccc(c2)N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L09 compound treatment 0.236 0.00994 1.37 0.239 0.00887 1.28 1.8772 0.9994 1490753 TimTec1_000603 CC(O)(C#CC1(CC2CC3CC(C2)C1)C3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L10 compound treatment 0.219 -0.00706 -0.98 0.216 -0.0141 -2.04 -2.1326 -0.943 1577974 TimTec1_000604 O=C(NC1CCCCC1)C2CCCN2C(=O)Oc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L11 compound treatment 0.248 0.0219 3.03 0.249 0.0189 2.73 4.0709 0.9986 1352134 TimTec1_000605 Cc1ccc(Nc2nc(cs2)c3ccc(cc3)S(=O)(=O)N4CCCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L12 compound treatment 0.223 -0.00306 -0.42 0.221 -0.00912 -1.32 -1.2312 -0.8894 1230716 TimTec1_000606 Fc1ccc(cc1F)C(=O)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L13 compound treatment 0.232 0.00594 0.82 0.227 -0.00312 -0.45 0.2608 0.2786 1741888 TimTec1_000607 Cn1c2OC(=C(C#N)C(c3ccccc3)c2c(=O)n(C)c1=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L14 compound treatment 0.252 0.0259 3.58 0.244 0.0139 2.0 3.9509 0.9623 1654001 TimTec1_000608 O=c1oc2ccccc2cc1c3ccc4OCOc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L15 compound treatment 0.24 0.0139 1.93 0.222 -0.00812 -1.17 0.5316 0.2358 3210778 TimTec1_000609 CC(C)(C)c1ccc(cc1)C(=O)CC(NCc2ccccc2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L16 compound treatment 0.231 0.00494 0.68 0.228 -0.00212 -0.31 0.2653 0.3547 1345015 TimTec1_000610 CC(O)CN1CC2CC(C1)c3cccc(=O)n3C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L17 compound treatment 0.236 0.00994 1.37 0.231 8.75E-4 0.13 1.0601 0.769 3210779 TimTec1_000611 CS/C(=N\C#N)/Nc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L18 compound treatment 0.227 9.38E-4 0.13 0.225 -0.00512 -0.74 -0.4319 -0.5747 1173928 TimTec1_000612 CC(=O)Oc1ccc(cc1)C(=O)N2CCc3ccccc3C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L19 compound treatment 0.225 -0.00106 -0.15 0.223 -0.00712 -1.03 -0.8315 -0.7999 3382 TimTec1_000613 Cc1c(CCO)sc[n+]1Cc2cnc(C)nc2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L20 compound treatment 0.228 0.00194 0.27 0.223 -0.00712 -1.03 -0.5385 -0.5064 3210780 TimTec1_000614 COc1ccc(CNC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L21 compound treatment 0.263 0.0369 5.1 0.255 0.0249 3.59 6.149 0.9853 1705753 TimTec1_000615 CC1(OCCO1)c2ccc3noc(c4ccccc4)c3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L22 compound treatment 0.22 -0.00606 -0.84 0.221 -0.00912 -1.32 -1.5242 -0.976 1592926 TimTec1_000616 CC(C)(C)c1ccc(cc1)C(=O)N(CC#N)CC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L23 mock treatment 0.227 9.38E-4 0.13 0.23 -1.25E-4 -0.02 0.0788 0.6027 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 L24 positive control 0.226 -6.25E-5 -0.01 0.23 -1.25E-4 -0.02 -0.0189 -0.943 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M01 compound treatment 0.235 0.00894 1.23 0.228 -0.00212 -0.31 0.656 0.5156 1026530 TimTec1_000617 Cc1cccc(c1)C(=O)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M02 compound treatment 0.228 0.00194 0.27 0.229 -0.00112 -0.16 0.0744 0.2375 3081201 TimTec1_000618 COCn1nc(oc1=S)c2ccccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M03 compound treatment 0.224 -0.00206 -0.28 0.224 -0.00612 -0.88 -0.8271 -0.8898 1048496 TimTec1_000619 Cc1ccccc1NC(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M04 compound treatment 0.262 0.0359 4.96 0.267 0.0369 5.33 7.277 0.9994 1139431 TimTec1_000620 CCC(Oc1ccccc1)C(=O)Nc2sc3CCCCc3c2C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M05 compound treatment 0.271 0.0449 6.21 0.269 0.0389 5.62 8.3605 0.9987 3081204 TimTec1_000621 O=C(NCSc1nc2ccccc2s1)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M06 compound treatment 0.227 9.38E-4 0.13 0.229 -0.00112 -0.16 -0.0233 -0.1122 3081205 TimTec1_000622 COC(=O)c1c(I)cnn1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M07 compound treatment 0.255 0.0289 4.0 0.249 0.0189 2.73 4.7547 0.9826 3210781 TimTec1_000623 C(/N=C/c1cccnc1)c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M08 compound treatment 0.23 0.00394 0.54 0.218 -0.0121 -1.75 -0.8538 -0.4655 1442529 TimTec1_000624 Cc1c(cccc1C(=O)c2ccccc2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M09 compound treatment 0.228 0.00194 0.27 0.223 -0.00712 -1.03 -0.5385 -0.5064 1549357 TimTec1_000625 COc1c(O)cc2CCCC(=O)Cc2c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M10 compound treatment 0.243 0.0169 2.34 0.243 0.0129 1.86 2.9696 0.9935 1364990 TimTec1_000626 CC(C)OC(=O)c1c(N)sc2CC(C)CCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M11 compound treatment 0.227 9.38E-4 0.13 0.225 -0.00512 -0.74 -0.4319 -0.5747 1248596 TimTec1_000627 O=C(Cc1ccccc1)Sc2nc3ccccc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M12 compound treatment 0.221 -0.00506 -0.7 0.222 -0.00812 -1.17 -1.3244 -0.9694 3210782 TimTec1_000628 NNC(=O)CCCNc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M13 compound treatment 0.244 0.0179 2.48 0.245 0.0149 2.15 3.2716 0.9975 1664419 TimTec1_000629 O=C(Nc1ccc(Cc2ccc(NC(=O)C3CC3)cc2)cc1)C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M14 compound treatment 0.225 -0.00106 -0.15 0.22 -0.0101 -1.46 -1.1379 -0.7742 3081210 TimTec1_000630 COc1cccc(OCCNC(=O)c2cccc3ccccc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M15 compound treatment 0.273 0.0469 6.48 0.276 0.0459 6.63 9.2708 0.9999 1630369 TimTec1_000631 C(Cc1ccco1)C2=NCCn3cccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M16 compound treatment 0.225 -0.00106 -0.15 0.223 -0.00712 -1.03 -0.8315 -0.7999 3210783 TimTec1_000632 CC1CC(CC(C)(C)C1)NC(=O)c2ccc(Br)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M17 compound treatment 0.29 0.0639 8.83 0.288 0.0579 8.36 12.1572 0.9996 2106961 TimTec1_000633 O=S(=O)(Nc1nc2ccccc2nc1[n+]3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M18 compound treatment 0.228 0.00194 0.27 0.224 -0.00612 -0.88 -0.4363 -0.472 1408031 TimTec1_000634 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4o3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M19 compound treatment 0.225 -0.00106 -0.15 0.226 -0.00412 -0.6 -0.5251 -0.8557 1186272 TimTec1_000635 O=C(OCC1CCCN2CCCCC12)C3CCNCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M20 compound treatment 0.231 0.00494 0.68 0.229 -0.00112 -0.16 0.3674 0.524 3210784 TimTec1_000636 S(C(c1ccccc1)c2ccccc2)c3ccccn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M21 compound treatment 0.219 -0.00706 -0.98 0.217 -0.0131 -1.9 -2.0305 -0.9523 1230906 TimTec1_000637 Brc1cccc(c1)C(=O)NCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M22 compound treatment 0.224 -0.00206 -0.28 0.225 -0.00512 -0.74 -0.7249 -0.9139 3081216 TimTec1_000638 COc1ccc(cc1)c2nnc(SCc3ccc(F)cc3)n2c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M23 mock treatment 0.226 -6.25E-5 -0.01 0.232 0.00188 0.27 0.1854 0.6842 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 M24 positive control 0.225 -0.00106 -0.15 0.226 -0.00412 -0.6 -0.5251 -0.8557 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N01 compound treatment 0.225 -0.00106 -0.15 0.219 -0.0111 -1.61 -1.2401 -0.7685 3210785 TimTec1_000639 O=C(CSc1ccccn1)NCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N02 compound treatment 0.221 -0.00506 -0.7 0.224 -0.00612 -0.88 -1.1201 -0.9932 3081217 TimTec1_000640 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N03 compound treatment 0.221 -0.00506 -0.7 0.222 -0.00812 -1.17 -1.3244 -0.9694 3210786 TimTec1_000641 Cc1ccc2nc(oc2c1)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N04 compound treatment 0.223 -0.00306 -0.42 0.226 -0.00412 -0.6 -0.7205 -0.9859 1304545 TimTec1_000642 CC1(O)N(CCc2ccccc2)C(=O)OC31CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N05 compound treatment 0.23 0.00394 0.54 0.234 0.00388 0.56 0.7804 0.9999 3081220 TimTec1_000643 CN1C(=O)/C(=c/2\sc3nc(nn3c2=O)c4ccccc4)/c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N06 compound treatment 0.229 0.00294 0.41 0.231 8.75E-4 0.13 0.3763 0.8854 1284486 TimTec1_000644 CC1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N07 compound treatment 0.223 -0.00306 -0.42 0.22 -0.0101 -1.46 -1.3333 -0.8758 1505391 TimTec1_000645 CC(Oc1ccccc1OC(=O)C)c2nn(C(=O)C)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N08 compound treatment 0.228 0.00194 0.27 0.219 -0.0111 -1.61 -0.947 -0.5813 3210905 TimTec1_000646 OCCCn/1c(cs\c1=N/c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N09 compound treatment 0.236 0.00994 1.37 0.238 0.00787 1.14 1.7751 0.9956 3210906 TimTec1_000647 CSc1nc(N)nc(SCC(=O)Nc2ccccc2)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N10 compound treatment 0.353 0.127 17.54 0.357 0.127 18.33 25.359 0.9998 1155124 TimTec1_000648 CC(C)CC(C(=O)N)C1=NC(C)(C)Cc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N11 compound treatment 0.218 -0.00806 -1.11 0.222 -0.00812 -1.17 -1.6175 -0.9997 1713559 TimTec1_000649 CSc1nc2ccc(NC(=O)CCc3ccccc3)cc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N12 compound treatment 0.22 -0.00606 -0.84 0.22 -0.0101 -1.46 -1.6264 -0.965 3081224 TimTec1_000650 CC(=C)C1CCC2(C)OC(=O)N(Cc3ccccc3)C12C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N13 compound treatment 0.286 0.0599 8.28 0.274 0.0439 6.34 10.3365 0.9913 1489806 TimTec1_000651 Clc1ccc(cc1)C2=CC(c3ccccc3)n4ncnc4N2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N14 compound treatment 0.213 -0.0131 -1.8 0.212 -0.0181 -2.62 -3.1273 -0.9835 1607919 TimTec1_000652 CC(C)C(=O)OCC1CCCN2CCCCC12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N15 compound treatment 0.249 0.0229 3.17 0.247 0.0169 2.44 3.9643 0.9916 3081227 TimTec1_000653 Oc1ccccc1/C=N/c2ncc(cc2Cl)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N16 compound treatment 0.226 -6.25E-5 -0.01 0.223 -0.00712 -1.03 -0.7338 -0.713 1250530 TimTec1_000654 Cc1ccc(C)c(NC(=O)CC(Cc2ccccc2)C(=O)O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N17 compound treatment 0.233 0.00694 0.96 0.232 0.00188 0.27 0.8692 0.8727 3081228 TimTec1_000655 CS/C(=N\C#N)/Nc1ccc(C)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N18 compound treatment 0.224 -0.00206 -0.28 0.222 -0.00812 -1.17 -1.0314 -0.854 3210907 TimTec1_000656 CCN(CC)C(=O)c1ccc(OC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N19 compound treatment 0.265 0.0389 5.38 0.265 0.0349 5.04 7.3658 0.9995 2709 TimTec1_000657 Cc1ncc(CO)c(CO)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N20 compound treatment 0.221 -0.00506 -0.7 0.22 -0.0101 -1.46 -1.5287 -0.943 3081230 TimTec1_000658 CCN(Cc1ccccc1)C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N21 compound treatment 0.227 9.38E-4 0.13 0.231 8.75E-4 0.13 0.181 0.9999 3210908 TimTec1_000659 FC(F)(F)c1nc2ccccc2nc1c3cccc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N22 compound treatment 0.219 -0.00706 -0.98 0.218 -0.0121 -1.75 -1.9283 -0.9618 1661635 TimTec1_000660 CC(C)(C)c1ccc(cc1)C(=O)NCCN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N23 mock treatment 0.225 -0.00106 -0.15 0.23 -1.25E-4 -0.02 -0.1166 -0.7881 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 N24 positive control 0.224 -0.00206 -0.28 0.228 -0.00212 -0.31 -0.4185 -0.9993 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O01 compound treatment 0.237 0.0109 1.51 0.226 -0.00412 -0.6 0.6471 0.3984 1674716 TimTec1_000661 COc1ccc(CC(=O)N2CCN(CC2)c3ccccc3OC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O02 compound treatment 0.222 -0.00406 -0.56 0.223 -0.00712 -1.03 -1.1246 -0.9593 1336284 TimTec1_000662 COc1c2CC(Oc2nc3ccccc13)C(C)(O)CO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O03 compound treatment 0.216 -0.0101 -1.39 0.22 -0.0101 -1.46 -2.0171 -0.9997 1432196 TimTec1_000663 O=C(Cc1ccccc1)NCCN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O04 compound treatment 0.214 -0.0121 -1.67 0.22 -0.0101 -1.46 -2.2125 -0.9979 1552779 TimTec1_000664 CCC(C(=O)Nc1cccc(NC(=O)C)c1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O05 compound treatment 0.221 -0.00506 -0.7 0.225 -0.00512 -0.74 -1.018 -0.9996 3210909 TimTec1_000665 CC(C)(C)/N=C/1\OC(NC(=S)N1c2ccccc2)(c3ccccc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O06 compound treatment 0.22 -0.00606 -0.84 0.224 -0.00612 -0.88 -1.2178 -0.9996 3081248 TimTec1_000666 Cn1ncc(Br)c1C(=O)NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O07 compound treatment 0.226 -6.25E-5 -0.01 0.223 -0.00712 -1.03 -0.7338 -0.713 1391171 TimTec1_000667 O=C(Cc1ccccc1)SC2=NCCS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O08 compound treatment 0.223 -0.00306 -0.42 0.225 -0.00512 -0.74 -0.8226 -0.9648 1548144 TimTec1_000668 Nc1ccccc1N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O09 compound treatment 0.221 -0.00506 -0.7 0.225 -0.00512 -0.74 -1.018 -0.9996 1262651 TimTec1_000669 OC(=O)c1ccccc1OCc2ccc3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O10 compound treatment 0.23 0.00394 0.54 0.235 0.00487 0.7 0.8826 0.9919 1660487 TimTec1_000670 Cc1cc(Nc2ccccc2)nc(Nc3ccccc3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O11 compound treatment 0.287 0.0609 8.42 0.289 0.0589 8.5 11.9662 1.0 3210910 TimTec1_000671 N#Cc1cnoc1N2CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O12 compound treatment 0.211 -0.0151 -2.08 0.215 -0.0151 -2.18 -3.0163 -0.9997 1484966 TimTec1_000672 CN1CCN(CC(O)COc2ccc3ccccc3c2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O13 compound treatment 0.381 0.155 21.4 0.369 0.139 20.06 29.32 0.9995 1229967 TimTec1_000673 COc1ccc2nc(C)cc(N3CCOCC3)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O14 compound treatment 0.227 9.38E-4 0.13 0.226 -0.00412 -0.6 -0.3297 -0.5408 3210911 TimTec1_000674 Cc1ccc(OCCNC(=O)c2ccc(cc2)C(C)(C)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O15 compound treatment 0.215 -0.0111 -1.53 0.224 -0.00612 -0.88 -1.7063 -0.9662 1008172 TimTec1_000675 O=C(N(C1CCCCC1)C2CCCCC2)c3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O16 compound treatment 0.221 -0.00506 -0.7 0.221 -0.00912 -1.32 -1.4266 -0.9561 1563007 TimTec1_000676 CS(=O)(=O)NCc1cccc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O17 compound treatment 0.356 0.13 17.95 0.317 0.0869 12.55 21.5666 0.9847 3210912 TimTec1_000677 CC1=NN(C(=O)C1/C=C/2\SC(=S)N(CC3CCCO3)C2=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O18 compound treatment 0.218 -0.00806 -1.11 0.222 -0.00812 -1.17 -1.6175 -0.9997 1336524 TimTec1_000678 O=C(NCc1ccccn1)C(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O19 compound treatment 0.22 -0.00606 -0.84 0.219 -0.0111 -1.61 -1.7285 -0.9539 1536621 TimTec1_000679 CC(=O)NCC1CCCN2CCCCC12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O20 compound treatment 0.221 -0.00506 -0.7 0.222 -0.00812 -1.17 -1.3244 -0.9694 1425414 TimTec1_000680 CCOc1ccc2nc(SCC(=O)N3CCOCC3)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O21 compound treatment 0.207 -0.0191 -2.63 0.212 -0.0181 -2.62 -3.7134 -1.0 3210913 TimTec1_000681 C[N+]1(CCOCC2CCC[N+]3(C)CCCCC23)CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O22 compound treatment 0.22 -0.00606 -0.84 0.223 -0.00712 -1.03 -1.32 -0.9948 3081257 TimTec1_000682 Nc1nnc(SCC(=O)c2ccccc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O23 mock treatment 0.222 -0.00406 -0.56 0.23 -1.25E-4 -0.02 -0.4096 -0.7295 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 O24 positive control 0.22 -0.00606 -0.84 0.224 -0.00612 -0.88 -1.2178 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P01 compound treatment 0.228 0.00194 0.27 0.231 8.75E-4 0.13 0.2786 0.9413 3210914 TimTec1_000683 Cn1nnnc1SC(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P02 compound treatment 0.219 -0.00706 -0.98 0.221 -0.00912 -1.32 -1.6219 -0.989 1610147 TimTec1_000684 O=C(NC(c1ccccc1)c2ccccc2)c3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P03 compound treatment 0.283 0.0569 7.87 0.277 0.0469 6.77 10.3498 0.9972 3210915 TimTec1_000685 COC(=O)C1=C(C)N=C2SCCC(=O)N2C1c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P04 compound treatment 0.216 -0.0101 -1.39 0.22 -0.0101 -1.46 -2.0171 -0.9997 3210916 TimTec1_000686 CCCCS(=O)(=O)/C=C/C1C(C2CC1C=C2)S(=O)(=O)CCCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P05 compound treatment 0.225 -0.00106 -0.15 0.228 -0.00212 -0.31 -0.3208 -0.943 3081261 TimTec1_000687 Cc1c(NC(=O)/C(=C/c2ccccc2)/NC(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P06 compound treatment 0.227 9.38E-4 0.13 0.227 -0.00312 -0.45 -0.2276 -0.4847 3210917 TimTec1_000688 CCOC(=O)CN(C1=NS(=O)(=O)c2ccccc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P07 compound treatment 0.222 -0.00406 -0.56 0.221 -0.00912 -1.32 -1.3289 -0.9276 1583564 TimTec1_000689 OC(=O)c1ccccc1OCC(=O)NCCN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P08 compound treatment 0.23 0.00394 0.54 0.226 -0.00412 -0.6 -0.0367 -0.0455 1715711 TimTec1_000690 CC(C)N(C(C)C)C(=O)c1ccc(cc1)c2nnc(o2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P09 compound treatment 0.228 0.00194 0.27 0.233 0.00288 0.42 0.4829 0.9774 1353777 TimTec1_000691 Cc1cc2OC(=C(C#N)C(c3ccc(F)cc3)c2c(=O)o1)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P10 compound treatment 0.228 0.00194 0.27 0.256 0.0259 3.74 2.8321 0.7558 1375739 TimTec1_000692 CN(C)c1ccc(cc1)n2c(=O)c3cc4c(=O)n(c5ccc(cc5)N(C)C)c(=O)c4cc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P11 compound treatment 0.215 -0.0111 -1.53 0.217 -0.0131 -1.9 -2.4212 -0.9943 1562644 TimTec1_000693 COc1ccc(CNCC2(CCCC2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P12 compound treatment 0.222 -0.00406 -0.56 0.217 -0.0131 -1.9 -1.7374 -0.8787 1540542 TimTec1_000694 Cc1ccc(CCP(=O)(O)CCc2ccc(C)nc2)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P13 compound treatment 0.22 -0.00606 -0.84 0.223 -0.00712 -1.03 -1.32 -0.9948 1525917 TimTec1_000695 OC(=O)C(CC(=O)c1ccc(Br)cc1)SC2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P14 compound treatment 0.22 -0.00606 -0.84 0.219 -0.0111 -1.61 -1.7285 -0.9539 1646318 TimTec1_000696 O=C(Cc1ccccc1)OCC2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P15 compound treatment 0.22 -0.00606 -0.84 0.219 -0.0111 -1.61 -1.7285 -0.9539 3210918 TimTec1_000697 OC(=O)C(CC(=O)c1ccc(Cl)cc1)NC(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P16 compound treatment 0.224 -0.00206 -0.28 0.226 -0.00412 -0.6 -0.6228 -0.943 3081269 TimTec1_000698 CCCn1c(=O)n(CCC)c2c(C)cc(C)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P17 compound treatment 0.22 -0.00606 -0.84 0.223 -0.00712 -1.03 -1.32 -0.9948 3210919 TimTec1_000699 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)N3CCN(CC3)c4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P18 compound treatment 0.219 -0.00706 -0.98 0.214 -0.0161 -2.33 -2.3369 -0.9254 3081271 TimTec1_000700 CNC(=O)c1ccc(OC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P19 compound treatment 0.223 -0.00306 -0.42 0.22 -0.0101 -1.46 -1.3333 -0.8758 3081273 TimTec1_000701 Cn1cc(I)c(n1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P20 compound treatment 0.221 -0.00506 -0.7 0.218 -0.0121 -1.75 -1.733 -0.9189 3081274 TimTec1_000702 CCN(C(=O)C)c1ccccc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P21 compound treatment 0.218 -0.00806 -1.11 0.22 -0.0101 -1.46 -1.8218 -0.991 1207599 TimTec1_000703 Cc1ccc(cc1C)N2C(=O)c3ccc(cc3C2=O)C(=O)N(CCO)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P22 compound treatment 0.217 -0.00906 -1.25 0.216 -0.0141 -2.04 -2.328 -0.9725 1637859 TimTec1_000704 Clc1ccc(Cl)c(c1)C(=O)N(CC#N)CC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P23 mock treatment 0.224 -0.00206 -0.28 0.228 -0.00212 -0.31 -0.4185 -0.9993 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2064 P24 positive control 0.223 -0.00306 -0.42 0.23 -1.25E-4 -0.02 -0.3119 -0.7366 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A01 compound treatment 0.213 -0.0134 -1.85 0.216 -0.0106 -1.53 -2.3918 -0.9957 1509421 TimTec1_003873 OC(C1CN2CCC1CC2)(c3cccs3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A02 compound treatment 0.249 0.0226 3.13 0.243 0.0164 2.37 3.8827 0.9905 3085133 TimTec1_003874 Brc1ccc(NCCC(=O)c2ccc3OCOc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A03 compound treatment 0.213 -0.0134 -1.85 0.21 -0.0166 -2.4 -3.0046 -0.9916 1626877 TimTec1_003875 CCOC(=O)c1cc(sc1NC(=O)CCN2CCN(CC)CC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A04 compound treatment 0.208 -0.0184 -2.54 0.209 -0.0176 -2.55 -3.5952 -1.0 3211709 TimTec1_003876 COC(C(=O)NCc1ccc(Cl)cc1Cl)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A05 compound treatment 0.33 0.104 14.32 0.33 0.103 14.93 20.6814 0.9998 3085202 TimTec1_003877 Cc1ccc(Nc2c(O)[nH]c(=O)n2N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A06 compound treatment 0.236 0.00962 1.33 0.234 0.00738 1.07 1.6935 0.994 1917644 TimTec1_003878 CC1=C(C(=O)OCc2ccccc2)C3(O)C(=O)c4ccccc4C3(O)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A07 compound treatment 0.248 0.0216 2.99 0.257 0.0304 4.39 5.2149 0.9825 3211710 TimTec1_003879 C(N1CCN(CC1)c2ncnc3sc4CCCCCc4c23)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A08 compound treatment 0.27 0.0436 6.03 0.271 0.0444 6.41 8.794 0.9995 1084987 TimTec1_003880 OC(=O)c1ccc2nc(O)c(O)nc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A09 compound treatment 0.215 -0.0114 -1.57 0.21 -0.0166 -2.4 -2.8092 -0.9789 3211711 TimTec1_003881 CC(C)c1ccc(NC(=O)NCC2CCCO2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A10 compound treatment 0.246 0.0196 2.71 0.24 0.0134 1.93 3.2832 0.9862 1015637 TimTec1_003882 Clc1ccc(cc1)c2cc3ccccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A11 compound treatment 0.26 0.0336 4.65 0.252 0.0254 3.67 5.8765 0.9931 3211712 TimTec1_003883 Cn1cc(/C(=N\O)/Cc2ccccc2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A12 compound treatment 0.232 0.00563 0.78 0.233 0.00638 0.92 1.2006 0.9964 3211713 TimTec1_003884 Cc1nn(Cc2cccc(c2)C(=O)Nc3cccc(C)c3C)c(C)c1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A13 compound treatment 0.22 -0.00637 -0.88 0.211 -0.0156 -2.26 -2.2187 -0.9158 1851015 TimTec1_003885 CCc1ccc(OC(=O)COc2ccc(Br)c(C)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A14 compound treatment 0.211 -0.0154 -2.12 0.209 -0.0176 -2.55 -3.3021 -0.9959 3211714 TimTec1_003886 CC1(C)Cc2ccccc2C(=N1)NC(Cc3c[nH]c4ccccc34)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A15 compound treatment 0.218 -0.00837 -1.16 0.211 -0.0156 -2.26 -2.414 -0.9518 1208534 TimTec1_003887 COC(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2Br)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A16 compound treatment 0.24 0.0136 1.88 0.236 0.00937 1.35 2.2885 0.9869 1464409 TimTec1_003888 COc1ccc(OC)c2c(C)cc(=O)[nH]c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A17 compound treatment 0.211 -0.0154 -2.12 0.215 -0.0116 -1.68 -2.6893 -0.9932 1255944 TimTec1_003889 COC(=O)c1ccccc1NC(=O)c2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A18 compound treatment 0.222 -0.00437 -0.6 0.218 -0.00862 -1.25 -1.3083 -0.9448 3211715 TimTec1_003890 Cc1nnc(Sc2cc(C)nc3ccccc23)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A19 compound treatment 0.215 -0.0114 -1.57 0.214 -0.0126 -1.82 -2.4007 -0.9973 3211716 TimTec1_003891 CCOc1ccc(CC(=O)NC2CC(C)(C)N(C)C(C)(C)C2)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A20 compound treatment 0.211 -0.0154 -2.12 0.213 -0.0136 -1.97 -2.8936 -0.9993 225200 TimTec1_003892 Nc1ccn(C2CC(O)C(CO)O2)c(=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A21 compound treatment 0.212 -0.0144 -1.99 0.209 -0.0176 -2.55 -3.2044 -0.9925 3211717 TimTec1_003893 CC(NC(=O)Cc1c[nH]c2ccccc12)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A22 compound treatment 0.308 0.0816 11.28 0.303 0.0764 11.03 15.7746 0.9999 3085213 TimTec1_003894 Brc1cc(N/C=C\2/C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A23 mock treatment 0.221 -0.00537 -0.74 0.217 -0.00962 -1.39 -1.5082 -0.9568 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 A24 positive control 0.217 -0.00937 -1.3 0.212 -0.0146 -2.11 -2.4096 -0.9724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B01 compound treatment 0.226 -3.75E-4 -0.05 0.224 -0.00262 -0.38 -0.3047 -0.7963 3211718 TimTec1_003895 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cc(Br)c(=O)[nH]c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B02 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 3211719 TimTec1_003896 COC(=O)C1=NNC(C1c2ccccc2)C(=O)OC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B03 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 3085215 TimTec1_003897 CN1[C@H](CC(O)c2ccccc2)CCCC1CC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B04 compound treatment 0.27 0.0436 6.03 0.268 0.0414 5.98 8.4876 1.0 3211720 TimTec1_003898 CCOC(=O)CNc1nnc(c2ccccc2)c(c1C#N)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B05 compound treatment 0.266 0.0396 5.47 0.27 0.0434 6.27 8.3011 0.9977 3085217 TimTec1_003899 COc1c(N)cc(Oc2cccc(c2)C(F)(F)F)c3nc(C)cc(C)c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B06 compound treatment 0.224 -0.00237 -0.33 0.224 -0.00262 -0.38 -0.5001 -0.9974 1047737 TimTec1_003900 COC(=O)C1CN(C)CCC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B07 compound treatment 0.323 0.0966 13.35 0.394 0.167 24.18 26.5345 0.9608 3211721 TimTec1_003901 CC(C)(C)c1oc(cc1COCC(F)(F)F)C(=O)Nc2ccc3c(c2)oc4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B08 compound treatment 0.26 0.0336 4.65 0.254 0.0274 3.95 6.0808 0.9968 3211722 TimTec1_003902 CC(C)NC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B09 compound treatment 0.265 0.0386 5.34 0.275 0.0484 6.99 8.7141 0.9911 1305957 TimTec1_003903 Clc1cccc(Cl)c1CN(Cc2ccccc2)c3ncnc4[nH]cnc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B10 compound treatment 0.223 -0.00337 -0.47 0.225 -0.00162 -0.23 -0.4957 -0.9495 1515666 TimTec1_003904 NNC(=O)C1C2CCCCC12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B11 compound treatment 0.346 0.12 16.53 0.346 0.119 17.24 23.8787 0.9998 3211723 TimTec1_003905 OC(=O)C(=C1SCCS1)C(=O)/C=C/c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B12 compound treatment 0.358 0.132 18.18 0.357 0.13 18.83 26.1744 0.9998 3085287 TimTec1_003906 Cc1ccc(cc1)N2C(=O)C(=CC2(O)c3ccccc3)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B13 compound treatment 0.228 0.00163 0.22 0.227 3.75E-4 0.05 0.197 0.8532 1580685 TimTec1_003907 CCc1ccccc1NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B14 compound treatment 0.221 -0.00537 -0.74 0.222 -0.00462 -0.67 -0.9975 -0.9986 3211724 TimTec1_003908 COc1ccccc1N/C(=N\O)/c2nonc2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B15 compound treatment 0.294 0.0676 9.34 0.291 0.0644 9.3 13.1813 1.0 3085290 TimTec1_003909 Clc1ccc(cc1)c2ccc(/C=N/C3CCS(=O)(=O)C3)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B16 compound treatment 0.37 0.144 19.84 0.366 0.139 20.13 28.2659 1.0 3211725 TimTec1_003910 OC(=O)c1cccc(/N=C/c2ccc(cc2)N3CCOCC3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B17 compound treatment 0.27 0.0436 6.03 0.263 0.0364 5.25 7.9769 0.9977 3211726 TimTec1_003911 CCn1c(=O)c(/C=C\2/C(=O)NN=C2c3ccccc3)c(O)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B18 compound treatment 0.235 0.00862 1.19 0.235 0.00837 1.21 1.698 1.0 3085292 TimTec1_003912 C(=N/c1n[nH]c(\N=C\c2ccccc2)n1)\c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B19 compound treatment 0.265 0.0386 5.34 0.27 0.0434 6.27 8.2034 0.9968 3211727 TimTec1_003913 FC(F)(F)c1nnc(S)n1/N=C/c2c[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B20 compound treatment 0.223 -0.00337 -0.47 0.221 -0.00562 -0.81 -0.9042 -0.9652 3085294 TimTec1_003914 FC(F)(F)c1ccccc1NC(=O)CSc2ccccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B21 compound treatment 0.248 0.0216 2.99 0.252 0.0254 3.67 4.7043 0.9949 1454180 TimTec1_003915 Cc1nn(c(Cl)c1C2N(Cc3ccccc3)CCN2Cc4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B22 compound treatment 0.223 -0.00337 -0.47 0.221 -0.00562 -0.81 -0.9042 -0.9652 1565629 TimTec1_003916 CCOC(=O)c1c(CN(C)C)n(C)c2cc(Br)c(OC)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B23 mock treatment 0.227 6.25E-4 0.09 0.227 3.75E-4 0.05 0.0994 0.9748 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 B24 positive control 0.226 -3.75E-4 -0.05 0.225 -0.00162 -0.23 -0.2026 -0.8429 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C01 compound treatment 0.236 0.00962 1.33 0.241 0.0144 2.08 2.4085 0.9768 1262920 TimTec1_003917 CC(C)NC(=O)c1ccccc1CCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C02 compound treatment 0.235 0.00862 1.19 0.233 0.00638 0.92 1.4937 0.9919 3085297 TimTec1_003918 O=C(CCN1CCN(CC1)c2ccccc2)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C03 compound treatment 0.224 -0.00237 -0.33 0.223 -0.00362 -0.52 -0.6023 -0.9747 1344204 TimTec1_003919 COc1ccc(cc1)c2csc(NC(=O)Cc3cccc4ccccc34)c2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C04 compound treatment 0.282 0.0556 7.68 0.314 0.0874 12.62 14.3582 0.9717 3211824 TimTec1_003920 CC(NC(=O)c1ccc(CSc2ccccc2)cc1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C05 compound treatment 0.547 0.321 44.29 0.521 0.294 42.52 61.3881 0.9998 3085300 TimTec1_003921 NC1=NNC2=C(NNN12)c3ccccc3C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C06 compound treatment 0.23 0.00363 0.5 0.228 0.00138 0.2 0.4946 0.918 1738981 TimTec1_003922 O=c1n(nc(c2ccccc2)c3ccccc13)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C07 compound treatment 0.25 0.0236 3.26 0.254 0.0274 3.95 5.1039 0.9955 3085302 TimTec1_003923 COc1cc(/C=C/C)ccc1Oc2nnc(C)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C08 compound treatment 0.272 0.0456 6.3 0.269 0.0424 6.12 8.7851 0.9999 1410588 TimTec1_003924 Brc1cccc(NC(=O)c2ccc(OC3CSC3)cc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C09 compound treatment 0.224 -0.00237 -0.33 0.224 -0.00262 -0.38 -0.5001 -0.9974 1451839 TimTec1_003925 CC(C)c1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C10 compound treatment 0.251 0.0246 3.4 0.267 0.0404 5.83 6.5294 0.9671 3211825 TimTec1_003926 COc1ccc(c(OC)c1)c2oc3ccc(OC)cc3c(=O)c2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C11 compound treatment 0.258 0.0316 4.37 0.259 0.0324 4.68 6.3961 0.9994 1232921 TimTec1_003927 Cc1ccc(OC(=O)COc2ccc3ccccc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C12 compound treatment 0.238 0.0116 1.61 0.236 0.00937 1.35 2.0932 0.9964 1881298 TimTec1_003928 CC(C)(C)c1ccccc1NC(=O)c2cccc(Cn3cc(Cl)cn3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C13 compound treatment 0.226 -3.75E-4 -0.05 0.226 -6.25E-4 -0.09 -0.1005 -0.9652 3085306 TimTec1_003929 CCc1ccc(OC(=O)c2ccc(C)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C14 compound treatment 0.311 0.0846 11.69 0.295 0.0684 9.88 15.2505 0.9965 3211826 TimTec1_003930 NS(=O)(=O)c1ccc(Nc2nc(cs2)c3cccs3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C15 compound treatment 0.276 0.0496 6.86 0.278 0.0514 7.42 10.0951 0.9992 1544060 TimTec1_003931 Brc1c(OCC(=O)NCCC2=CCCCC2)ccc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C16 compound treatment 0.267 0.0406 5.61 0.266 0.0394 5.69 7.9903 1.0 1058123 TimTec1_003932 COc1ccc(OC)c2c(C)cc(Cl)nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C17 compound treatment 0.229 0.00263 0.36 0.23 0.00338 0.49 0.6011 0.9894 1506791 TimTec1_003933 CCC(CC)NC(=O)c1ccc(OC)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C18 compound treatment 0.227 6.25E-4 0.09 0.226 -6.25E-4 -0.09 -0.0028 -0.0223 1441088 TimTec1_003934 OC(=O)C(NC(=O)CSc1nnnn1c2ccccc2)(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C19 compound treatment 0.228 0.00163 0.22 0.227 3.75E-4 0.05 0.197 0.8532 3085378 TimTec1_003935 CN(C)c1nc(N)nc(Cn2ccnc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C20 compound treatment 0.224 -0.00237 -0.33 0.226 -6.25E-4 -0.09 -0.2958 -0.8694 3211827 TimTec1_003936 NNc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C21 compound treatment 0.221 -0.00537 -0.74 0.221 -0.00562 -0.81 -1.0996 -0.999 1668209 TimTec1_003937 Nc1nnnn1CC(=O)N(Cc2ccco2)C3(CCCCC3)C(=O)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C22 compound treatment 0.259 0.0326 4.51 0.26 0.0334 4.82 6.5959 0.9994 3211828 TimTec1_003938 COCCN1C(=C(C(=O)OC)/C(=C/c2c(Cl)cccc2Cl)/C1=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C23 mock treatment 0.227 6.25E-4 0.09 0.228 0.00138 0.2 0.2015 0.9304 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 C24 positive control 0.228 0.00163 0.22 0.228 0.00138 0.2 0.2992 0.9981 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D01 compound treatment 0.227 6.25E-4 0.09 0.226 -6.25E-4 -0.09 -0.0028 -0.0223 3085382 TimTec1_003939 CC(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C)n2cc(C)c(=O)[nH]c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D02 compound treatment 0.264 0.0376 5.2 0.273 0.0464 6.7 8.4122 0.9921 3211829 TimTec1_003940 Fc1ccc(Nn2c(nc3ccccc3c2=O)c4ccccc4)c(F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D03 compound treatment 0.919 0.693 95.69 0.95 0.723 104.49 141.5453 0.999 3085384 TimTec1_003941 CCN(CC)/C=C/C(=O)c1ccccc1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D04 compound treatment 0.228 0.00163 0.22 0.23 0.00338 0.49 0.5035 0.938 1632200 TimTec1_003942 CCOC(=O)c1sc(NC(=O)CC)c(C(=O)OCC)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D05 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 3085386 TimTec1_003943 COc1cc2CC3(Cc2cc1OC)N(C)Cc4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D06 compound treatment 0.219 -0.00737 -1.02 0.221 -0.00562 -0.81 -1.295 -0.9937 3211830 TimTec1_003944 CNC(C)[C@@H](O)c1ccc(O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D07 compound treatment 0.226 -3.75E-4 -0.05 0.226 -6.25E-4 -0.09 -0.1005 -0.9652 1329060 TimTec1_003945 OCC1(CO)COC2(CCCCC2)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D08 compound treatment 0.273 0.0466 6.44 0.275 0.0484 6.99 9.4956 0.9992 3211831 TimTec1_003946 CCOC(=O)c1sc(nc1C)n2nc(C)cc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D09 compound treatment 0.413 0.187 25.78 0.433 0.206 29.81 39.3098 0.9974 3211832 TimTec1_003947 COc1ccc(cc1)N2CC(=O)N(/N=C/c3ccc(cc3)N(C)C)C2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D10 compound treatment 0.291 0.0646 8.93 0.27 0.0434 6.27 10.7433 0.985 3085389 TimTec1_003948 O=C(CSc1cccc(n1)c2ccccc2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D11 compound treatment 0.38 0.154 21.22 0.357 0.13 18.83 28.3236 0.9982 3211833 TimTec1_003949 O=C/1Nc2ccccc2\C1=N/N3C(=O)/C(=C/c4ccccc4)/N=C3c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D12 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 1282238 TimTec1_003950 CC(C)NC(=O)COc1ccc(Cl)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D13 compound treatment 0.254 0.0276 3.82 0.247 0.0204 2.94 4.7797 0.9918 1920102 TimTec1_003951 FC(F)(F)c1cccc(/N=C/2\C(=O)Nc3ccccc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D14 compound treatment 0.224 -0.00237 -0.33 0.223 -0.00362 -0.52 -0.6023 -0.9747 3085391 TimTec1_003952 COC1=CC(=O)OC21CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D15 compound treatment 0.263 0.0366 5.06 0.262 0.0354 5.11 7.191 1.0 3085393 TimTec1_003953 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D16 compound treatment 0.227 6.25E-4 0.09 0.227 3.75E-4 0.05 0.0994 0.9748 1168752 TimTec1_003954 CCOC(=O)C1=C(C)OC(=C(C(=O)OCC)C21C(=O)Nc3ccccc32)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D17 compound treatment 0.23 0.00363 0.5 0.232 0.00538 0.78 0.9031 0.9775 1702369 TimTec1_003955 COc1ccc(cc1)c2csc(n2)N3N=C(C)C(C(C(C#N)C(=O)N)c4ccc(Cl)cc4)C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D18 compound treatment 0.242 0.0156 2.16 0.24 0.0134 1.93 2.8925 0.9985 3085395 TimTec1_003956 CCOC(=O)c1sc2c(OC)c(Br)ccc2c1NC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D19 compound treatment 0.566 0.34 46.92 0.564 0.337 48.73 67.6361 0.9998 3085397 TimTec1_003957 CC1(C)CC(=O)C(=CNc2ncnc3[nH]cnc23)C(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D20 compound treatment 0.221 -0.00537 -0.74 0.222 -0.00462 -0.67 -0.9975 -0.9986 1514121 TimTec1_003958 O=C(CCc1ccccc1)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D21 compound treatment 0.266 0.0396 5.47 0.266 0.0394 5.69 7.8926 0.9998 3211834 TimTec1_003959 OCCNc1ccn(c2nc(sc2c3ccccc3)c4ccccc4)c(=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D22 compound treatment 0.219 -0.00737 -1.02 0.22 -0.00662 -0.96 -1.3971 -0.9995 1914384 TimTec1_003960 Cc1ccc(CCSCC(=O)O)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D23 mock treatment 0.229 0.00263 0.36 0.229 0.00238 0.34 0.499 0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 D24 positive control 0.229 0.00263 0.36 0.229 0.00238 0.34 0.499 0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E01 compound treatment 0.22 -0.00637 -0.88 0.222 -0.00462 -0.67 -1.0951 -0.9907 1410817 TimTec1_003961 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCCCCC4)cc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E02 compound treatment 0.239 0.0126 1.74 0.237 0.0104 1.5 2.293 0.9971 3085400 TimTec1_003962 CC(C)c1ccc(cc1)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)Nc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E03 compound treatment 0.454 0.228 31.45 0.454 0.227 32.84 45.4599 0.9998 1389044 TimTec1_003963 Cc1ccc(o1)C(=O)Nc2sc3CCCCc3c2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E04 compound treatment 0.219 -0.00737 -1.02 0.219 -0.00762 -1.1 -1.4993 -0.9992 3084361 TimTec1_003964 Brc1cccc(c1)c2n[nH]c(=S)[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E05 compound treatment 0.221 -0.00537 -0.74 0.219 -0.00762 -1.1 -1.3039 -0.9816 3211835 TimTec1_003965 O=C(NCCOc1ccccc1)c2ccc(=O)[nH]c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E06 compound treatment 0.255 0.0286 3.95 0.252 0.0254 3.67 5.3881 0.9993 3084365 TimTec1_003966 S=C(NCc1ccccc1)Nc2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E07 compound treatment 0.223 -0.00337 -0.47 0.223 -0.00362 -0.52 -0.6999 -0.9983 1680390 TimTec1_003967 CN1CCN(CC1)c2ncnc3sc(C)c(c4ccccc4)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E08 compound treatment 0.224 -0.00237 -0.33 0.222 -0.00462 -0.67 -0.7044 -0.9464 1123501 TimTec1_003968 COC(C(=O)NCc1ccc(OC)cc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E09 compound treatment 0.283 0.0566 7.82 0.28 0.0534 7.71 10.9832 1.0 3211836 TimTec1_003969 Clc1ccc(NC(=O)N(Cc2ccccc2)Cc3ccccc3)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E10 compound treatment 0.22 -0.00637 -0.88 0.219 -0.00762 -1.1 -1.4016 -0.9939 1804050 TimTec1_003970 CC(SCc1ccccc1)C(=O)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E11 compound treatment 0.22 -0.00637 -0.88 0.218 -0.00862 -1.25 -1.5037 -0.9856 1707898 TimTec1_003971 Cc1ccc(o1)C(O)c2nccn2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E12 compound treatment 0.229 0.00263 0.36 0.228 0.00138 0.2 0.3969 0.9598 3211977 TimTec1_003972 CCc1c(C)sc(NC(=O)CCCC(=O)O)c1C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E13 compound treatment 0.26 0.0336 4.65 0.263 0.0364 5.25 7.0 0.9981 1707943 TimTec1_003973 CCOc1ccc(NC(=O)CCC(=O)n2nc(cc2c3ccccc3)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E14 compound treatment 0.287 0.0606 8.38 0.272 0.0454 6.55 10.5568 0.9926 3211915 TimTec1_003974 Cc1ccc(Nc2nc(Nc3ccc(C)cc3)nc(Sc4nnc[nH]4)n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E15 compound treatment 0.259 0.0326 4.51 0.263 0.0364 5.25 6.9023 0.9971 1558319 TimTec1_003975 Brc1c(OCC(=O)NC2CCCCC2)ccc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E16 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 3084371 TimTec1_003976 O=S(=O)(Nc1cccc(c1)C2OCCCO2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E17 compound treatment 0.255 0.0286 3.95 0.252 0.0254 3.67 5.3881 0.9993 1490598 TimTec1_003977 Brc1ccccc1NC(=O)c2ccccc2Oc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E18 compound treatment 0.267 0.0406 5.61 0.26 0.0334 4.82 7.3774 0.9971 1419531 TimTec1_003978 CC1(C)CC(CCO1)n2c(NCCO)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E19 compound treatment 0.22 -0.00637 -0.88 0.219 -0.00762 -1.1 -1.4016 -0.9939 3084373 TimTec1_003979 O=C(NC(Cc1ccccc1)C(=O)N2CCCCC2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E20 compound treatment 0.22 -0.00637 -0.88 0.221 -0.00562 -0.81 -1.1973 -0.9992 3211916 TimTec1_003980 CC1CN(C2CC(O)C(CO)O2)C(=O)NC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E21 compound treatment 0.217 -0.00937 -1.3 0.219 -0.00762 -1.1 -1.6946 -0.9967 1203573 TimTec1_003981 O=C1CC2CS(=O)(=O)CC2N1c3ccc(Oc4ccccc4)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E22 compound treatment 0.216 -0.0104 -1.43 0.215 -0.0116 -1.68 -2.2009 -0.9969 3211917 TimTec1_003982 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccncc2)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E23 mock treatment 0.225 -0.00137 -0.19 0.226 -6.25E-4 -0.09 -0.1982 -0.9422 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 E24 positive control 0.229 0.00263 0.36 0.228 0.00138 0.2 0.3969 0.9598 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F01 compound treatment 0.242 0.0156 2.16 0.245 0.0184 2.65 3.4032 0.9947 1780915 TimTec1_003983 OCC1OC(Nc2ccc(cc2)C(=O)O)C(O)C1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F02 compound treatment 0.393 0.167 23.02 0.393 0.166 24.03 33.2705 0.9998 3211918 TimTec1_003984 CN1CCN(CC1)c2nsc(NO)c2Nc3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F03 compound treatment 0.257 0.0306 4.23 0.263 0.0364 5.25 6.707 0.9942 1313296 TimTec1_003985 Oc1ccccc1C(=O)c2cnn(c2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F04 compound treatment 0.409 0.183 25.23 0.399 0.172 24.9 35.4463 1.0 3211919 TimTec1_003986 COc1cc(/C=C\2/SC(=S)N(NC(=O)C)C2=O)ccc1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F05 compound treatment 0.133 -0.0934 -12.9 0.132 -0.0946 -13.67 -18.7864 -0.9996 3211920 TimTec1_003987 CN(C)c1ccc2N=c3cc(C)c(N)cc3=Sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F06 compound treatment 0.25 0.0236 3.26 0.254 0.0274 3.95 5.1039 0.9955 3084378 TimTec1_003988 COc1cc(O)c(C(=O)Cc2ccc(Cl)cc2)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F07 compound treatment 0.223 -0.00337 -0.47 0.218 -0.00862 -1.25 -1.2106 -0.9101 3211921 TimTec1_003989 CCOC(=O)NC(=S)N1CCN(CC1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F08 compound treatment 0.233 0.00663 0.92 0.238 0.0114 1.64 1.809 0.9618 3084380 TimTec1_003990 Cc1cc(c(C#N)c(SCC(=O)c2ccccc2)n1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F09 compound treatment 0.307 0.0806 11.14 0.351 0.124 17.97 20.5795 0.9736 3211922 TimTec1_003991 Fc1ccc(/C=N/N2C(=O)CN(C2=S)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F10 compound treatment 0.315 0.0886 12.24 0.307 0.0804 11.61 16.8669 0.9996 3084382 TimTec1_003992 Cc1cc(C(=O)Nc2ccccc2)c(o1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F11 compound treatment 0.319 0.0926 12.8 0.331 0.104 15.08 19.709 0.9967 3084969 TimTec1_003993 CCN(CC)C1=N/C(=C/c2ccccc2)/C(=O)N1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F12 compound treatment 0.235 0.00862 1.19 0.239 0.0124 1.79 2.1065 0.9806 3211923 TimTec1_003994 Brc1ccc(cc1)C(=O)NCCOc2ccccc2Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F13 compound treatment 0.314 0.0876 12.11 0.319 0.0924 13.34 17.9949 0.9988 3084971 TimTec1_003995 Oc1cc(O)c2sc3nc(cc(c3c2n1)C(F)(F)F)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F14 compound treatment 0.23 0.00363 0.5 0.227 3.75E-4 0.05 0.3924 0.779 1360453 TimTec1_003996 Cc1ccc(CCC2C3=C(CCCC3=O)OC4=C2C(=O)CCC4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F15 compound treatment 0.255 0.0286 3.95 0.267 0.0404 5.83 6.9201 0.9821 3084973 TimTec1_003997 CSc1oc(nc1S(=O)(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F16 compound treatment 0.224 -0.00237 -0.33 0.225 -0.00162 -0.23 -0.398 -0.9865 1588811 TimTec1_003998 CNC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F17 compound treatment 0.243 0.0166 2.3 0.239 0.0124 1.79 2.888 0.9923 3211924 TimTec1_003999 CCOc1ccc(cc1)C(C)(C)C(=O)NN2C(=O)/C(=C/c3ccccn3)/N=C2c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F18 compound treatment 0.286 0.0596 8.24 0.296 0.0694 10.02 12.9105 0.9953 3084976 TimTec1_004000 COc1ccc(/C=N/c2nc3ccc(Br)cc3s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F19 compound treatment 0.22 -0.00637 -0.88 0.22 -0.00662 -0.96 -1.2994 -0.9991 1627471 TimTec1_004001 O=S(=O)(NCc1ccncc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F20 compound treatment 0.219 -0.00737 -1.02 0.218 -0.00862 -1.25 -1.6014 -0.995 1030019 TimTec1_004002 CN(C)C(=O)c1ccccc1C(=O)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F21 compound treatment 0.258 0.0316 4.37 0.259 0.0324 4.68 6.3961 0.9994 3084978 TimTec1_004003 N#Cc1nc(oc1NCCCN2CCOCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F22 compound treatment 0.28 0.0536 7.41 0.272 0.0454 6.55 9.873 0.9981 1252023 TimTec1_004004 Cc1cccc(NC(=O)C2C3CCC=CCCC23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F23 mock treatment 0.226 -3.75E-4 -0.05 0.226 -6.25E-4 -0.09 -0.1005 -0.9652 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 F24 positive control 0.228 0.00163 0.22 0.228 0.00138 0.2 0.2992 0.9981 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G01 compound treatment 0.235 0.00862 1.19 0.23 0.00338 0.49 1.1873 0.9222 1401883 TimTec1_004005 Cc1c(C)c2ccccc2n1CC(O)CNCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G02 compound treatment 0.22 -0.00637 -0.88 0.219 -0.00762 -1.1 -1.4016 -0.9939 3084981 TimTec1_004006 O=C1OCc2cc(ccc12)n3cnnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G03 compound treatment 0.27 0.0436 6.03 0.272 0.0454 6.55 8.8962 0.9991 3211925 TimTec1_004007 Cc1sc2ncnc(N3CCN(CC3)c4cccc(c4)C(F)(F)F)c2c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G04 compound treatment 0.276 0.0496 6.86 0.276 0.0494 7.13 9.8908 0.9998 1527185 TimTec1_004008 COc1ccccc1c2cc(=O)c3ccccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G05 compound treatment 0.316 0.0896 12.38 0.305 0.0784 11.32 16.7604 0.999 1639456 TimTec1_004009 Oc1ccccc1C(Nc2ccccn2)c3ccc4cccnc4c3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G06 compound treatment 0.23 0.00363 0.5 0.225 -0.00162 -0.23 0.1881 0.3402 1650064 TimTec1_004010 Oc1ccccc1C(=O)NCCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G07 compound treatment 0.224 -0.00237 -0.33 0.221 -0.00562 -0.81 -0.8065 -0.9204 1085927 TimTec1_004011 CC1CCCCN1C(=O)Nc2cccc(c2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G08 compound treatment 0.272 0.0456 6.3 0.271 0.0444 6.41 8.9894 1.0 3085053 TimTec1_004012 O=C(N[C@@H]1C[C@H]2CC[C@@H]1C2)c3ccc(CSc4ccccc4)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G09 compound treatment 0.277 0.0506 6.99 0.271 0.0444 6.41 9.4778 0.9991 1516181 TimTec1_004013 C1CN(CC1c2ccccc2)c3nc(cs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G10 compound treatment 0.222 -0.00437 -0.6 0.218 -0.00862 -1.25 -1.3083 -0.9448 3211926 TimTec1_004014 OC(=O)c1ccccc1NC(=O)CCSc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G11 compound treatment 0.245 0.0186 2.57 0.239 0.0124 1.79 3.0834 0.9842 1741292 TimTec1_004015 CCCOC(=O)c1ccc(NC(=O)c2ccc(C)c(Br)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G12 compound treatment 0.315 0.0886 12.24 0.317 0.0904 13.05 17.8883 0.9995 3211927 TimTec1_004016 C1CN(CCO1)c2ccc(/N=C/c3ccc(Sc4nc5ccccc5[nH]4)o3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G13 compound treatment 0.284 0.0576 7.96 0.274 0.0474 6.84 10.4681 0.9972 1267880 TimTec1_004017 COC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G14 compound treatment 0.286 0.0596 8.24 0.276 0.0494 7.13 10.8677 0.9974 3211928 TimTec1_004018 OC(=O)/C(=C\c1ccco1)/NC(=O)c2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G15 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 1175724 TimTec1_004019 Cc1ccc(NC(=O)c2ccco2)cc1F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G16 compound treatment 0.221 -0.00537 -0.74 0.22 -0.00662 -0.96 -1.2017 -0.9921 3211929 TimTec1_004020 Cc1ccc(NCC(=O)SCc2csc(Nc3ccccc3)n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G17 compound treatment 0.249 0.0226 3.13 0.248 0.0214 3.09 4.3934 1.0 3085059 TimTec1_004021 COc1ccccc1c2nnc(o2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G18 compound treatment 0.28 0.0536 7.41 0.279 0.0524 7.57 10.588 0.9999 3211930 TimTec1_004022 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G19 compound treatment 0.221 -0.00537 -0.74 0.221 -0.00562 -0.81 -1.0996 -0.999 3211931 TimTec1_004023 CC(C)CSCC1OC(C(O)C1O)n2cnc3c(N)ncnc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G20 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 907315 TimTec1_004024 CCc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G21 compound treatment 0.22 -0.00637 -0.88 0.219 -0.00762 -1.1 -1.4016 -0.9939 1121708 TimTec1_004025 COc1cccc(NC(=O)COc2ccccc2OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G22 compound treatment 0.217 -0.00937 -1.3 0.22 -0.00662 -0.96 -1.5925 -0.9889 1216245 TimTec1_004026 Fc1ccc(cc1)S(=O)(=O)N(CC(=O)NCC2CCCO2)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G23 mock treatment 0.228 0.00163 0.22 0.229 0.00238 0.34 0.4013 0.9789 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 G24 positive control 0.225 -0.00137 -0.19 0.226 -6.25E-4 -0.09 -0.1982 -0.9422 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H01 compound treatment 0.225 -0.00137 -0.19 0.226 -6.25E-4 -0.09 -0.1982 -0.9422 1279518 TimTec1_004027 Nc1cnn(C2OC(COC(=O)c3ccccc3)C(O)C2O)c(=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H02 compound treatment 0.224 -0.00237 -0.33 0.221 -0.00562 -0.81 -0.8065 -0.9204 3211932 TimTec1_004028 Cc1ccc(C)c(NS(=O)(=O)c2ccc(NC(=N)Nc3nncc(C)n3)cc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H03 compound treatment 0.296 0.0696 9.62 0.318 0.0914 13.2 16.1344 0.9879 1187682 TimTec1_004029 COc1ccc(cc1)c2cc(CC(C)C)nc(N)c2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H04 compound treatment 0.244 0.0176 2.43 0.247 0.0204 2.94 3.8028 0.9956 1408114 TimTec1_004030 CCc1ccccc1NC(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H05 compound treatment 0.223 -0.00337 -0.47 0.217 -0.00962 -1.39 -1.3128 -0.8952 3211978 TimTec1_004031 CN(C)c1ccc(CCNC(=O)c2ccco2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H06 compound treatment 0.319 0.0926 12.8 0.328 0.101 14.64 19.4026 0.9977 3085065 TimTec1_004032 COc1cccc(c1)c2cc(=O)c3ccc(O)cc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H07 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 3211979 TimTec1_004033 C1CN(CCO1)/C(=N\c2ccccc2)/Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H08 compound treatment 0.287 0.0606 8.38 0.289 0.0624 9.01 12.2932 0.9993 3211980 TimTec1_004034 FC(F)(F)c1cc(nc(SCC(=O)c2ccccc2)c1C#N)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H09 compound treatment 0.224 -0.00237 -0.33 0.221 -0.00562 -0.81 -0.8065 -0.9204 3085068 TimTec1_004035 CC(=O)Nc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H10 compound treatment 0.238 0.0116 1.61 0.24 0.0134 1.93 2.5017 0.9958 3211981 TimTec1_004036 Cc1cc(nc2sc(C(=O)Nc3ccc(cc3)C(=O)N)c(N)c12)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H11 compound treatment 0.225 -0.00137 -0.19 0.221 -0.00562 -0.81 -0.7088 -0.8495 3085069 TimTec1_004037 OCC1OC(Oc2cccc(O)c2CCCc3ccc(O)cc3)C(O)C(O)C1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H12 compound treatment 0.223 -0.00337 -0.47 0.222 -0.00462 -0.67 -0.8021 -0.9845 1309367 TimTec1_004038 O=C(N1CCOCC1)c2nc3ccccc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H13 compound treatment 0.322 0.0956 13.21 0.296 0.0694 10.02 16.4272 0.9907 1455904 TimTec1_004039 CCc1nc2sc(C#N)c(N)c2cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H14 compound treatment 0.223 -0.00337 -0.47 0.219 -0.00762 -1.1 -1.1085 -0.9268 1365090 TimTec1_004040 NC(=O)c1ccc(cc1)C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H15 compound treatment 0.242 0.0156 2.16 0.234 0.00738 1.07 2.2796 0.947 1421754 TimTec1_004041 COc1ccc(NCn2c3ccccc3c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H16 compound treatment 0.224 -0.00237 -0.33 0.223 -0.00362 -0.52 -0.6023 -0.9747 1486169 TimTec1_004042 Cc1ccc2N3CCN(C(CCCC(=O)c2c1)C3=O)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H17 compound treatment 0.267 0.0406 5.61 0.267 0.0404 5.83 8.0924 0.9998 3211982 TimTec1_004043 Cc1ccc(cc1)C2=NNC3(S2)C(=O)Nc4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H18 compound treatment 0.226 -3.75E-4 -0.05 0.226 -6.25E-4 -0.09 -0.1005 -0.9652 3085139 TimTec1_004044 Cc1ccc2nc(/N=C/c3ccc(Cl)cc3Cl)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H19 compound treatment 0.329 0.103 14.18 0.323 0.0964 13.92 19.8688 1.0 3211983 TimTec1_004045 CCn1nc(C)c(/N=C/c2ccc(N(C)C)c(Br)c2)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H20 compound treatment 0.22 -0.00637 -0.88 0.221 -0.00562 -0.81 -1.1973 -0.9992 1009941 TimTec1_004046 CC(=O)OC(C(=O)c1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H21 compound treatment 0.218 -0.00837 -1.16 0.217 -0.00962 -1.39 -1.8012 -0.9958 1132941 TimTec1_004047 CC1(C)CC(CC(C)(C)N1)N2CCC(O)(C(C2)C(=O)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H22 compound treatment 0.22 -0.00637 -0.88 0.221 -0.00562 -0.81 -1.1973 -0.9992 3085143 TimTec1_004048 Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Br)cc2)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H23 mock treatment 0.229 0.00263 0.36 0.23 0.00338 0.49 0.6011 0.9894 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 H24 positive control 0.224 -0.00237 -0.33 0.226 -6.25E-4 -0.09 -0.2958 -0.8694 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I01 compound treatment 0.311 0.0846 11.69 0.309 0.0824 11.9 16.6805 1.0 1679534 TimTec1_004049 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I02 compound treatment 0.253 0.0266 3.68 0.261 0.0344 4.97 6.1119 0.9891 3085145 TimTec1_004050 CN(C)c1nc(N)nc(COc2ccc(C)c(C)c2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I03 compound treatment 0.223 -0.00337 -0.47 0.222 -0.00462 -0.67 -0.8021 -0.9845 1257756 TimTec1_004051 O=c1ccc2ccc(Oc3nc(nc4ccccc34)c5cccnc5)cc2o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I04 compound treatment 0.215 -0.0114 -1.57 0.214 -0.0126 -1.82 -2.4007 -0.9973 1524978 TimTec1_004052 CCS(=O)(=O)N(CC(=O)N1CCCC1)c2ccc(OC)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I05 compound treatment 0.271 0.0446 6.16 0.296 0.0694 10.02 11.4452 0.9728 3211984 TimTec1_004053 FC(F)(F)c1cccc(Nc2ncnc3sc4CCCc4c23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I06 compound treatment 0.221 -0.00537 -0.74 0.222 -0.00462 -0.67 -0.9975 -0.9986 1023730 TimTec1_004054 NC(=N)SCc1ccc(Cl)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I07 compound treatment 0.235 0.00862 1.19 0.236 0.00937 1.35 1.8001 0.998 3211985 TimTec1_004055 CC1CCCC(C)N1C(=O)Nc2ccc(Cl)c(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I08 compound treatment 0.508 0.282 38.91 0.521 0.294 42.52 57.5783 0.999 3085148 TimTec1_004056 CCN(CC)c1ccc(/C=C/C#N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I09 compound treatment 0.225 -0.00137 -0.19 0.223 -0.00362 -0.52 -0.5046 -0.9059 3211986 TimTec1_004057 Cn1c(NC(=O)c2cc(F)c(F)cc2Cl)nc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I10 compound treatment 0.218 -0.00837 -1.16 0.216 -0.0106 -1.53 -1.9034 -0.9903 1379820 TimTec1_004058 CCOC(=O)CC(N)c1cccc(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I11 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 3211987 TimTec1_004059 Cc1ccc(CCC(=O)O)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I12 compound treatment 0.845 0.619 85.46 0.803 0.576 83.25 119.302 0.9999 3085152 TimTec1_004060 COc1ccc(/N=C/c2cccn2c3ccc(Br)cc3)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I13 compound treatment 0.282 0.0556 7.68 0.3 0.0734 10.6 12.9283 0.9875 3211988 TimTec1_004061 NS(=O)(=O)c1ccc(NC(=O)/C=C/c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I14 compound treatment 0.22 -0.00637 -0.88 0.215 -0.0116 -1.68 -1.8101 -0.9546 1519495 TimTec1_004062 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)CSc4nnc[nH]4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I15 compound treatment 0.233 0.00663 0.92 0.225 -0.00162 -0.23 0.4812 0.5093 1570543 TimTec1_004063 CCOc1ccc(NCC(=O)n2nc(C)cc2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I16 compound treatment 0.23 0.00363 0.5 0.228 0.00138 0.2 0.4946 0.918 3211989 TimTec1_004064 Cc1ccc(SCCNC(=O)c2ccc3ccccc3n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I17 compound treatment 0.221 -0.00537 -0.74 0.221 -0.00562 -0.81 -1.0996 -0.999 1040036 TimTec1_004065 OCC1OC(C(O)C1O)n2cnc3cncnc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I18 compound treatment 0.394 0.168 23.16 0.367 0.14 20.28 30.7126 0.9978 3085155 TimTec1_004066 S=C(NCc1ccco1)Nc2ccc3nc(c4ccccn4)c(nc3c2)c5ccccn5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I19 compound treatment 0.223 -0.00337 -0.47 0.227 3.75E-4 0.05 -0.2914 -0.6208 3211990 TimTec1_004067 OC(Cc1c[nH]c2ccccc12)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I20 compound treatment 0.22 -0.00637 -0.88 0.22 -0.00662 -0.96 -1.2994 -0.9991 3551456 TimTec1_004068 CN(C)c1ncnc2n(cnc12)C3OC(CO)C(N)C3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I21 compound treatment 0.215 -0.0114 -1.57 0.216 -0.0106 -1.53 -2.1964 -0.9999 1678356 TimTec1_004069 COc1ccc(cc1OC)c2n[nH]c(=S)n2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I22 compound treatment 0.357 0.131 18.05 0.368 0.141 20.42 27.2003 0.9981 1862685 TimTec1_004070 Fc1cccc(NC(=O)c2cccc(c2)c3cc4ccccc4oc3=O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I23 mock treatment 0.225 -0.00137 -0.19 0.227 3.75E-4 0.05 -0.096 -0.4861 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 I24 positive control 0.222 -0.00437 -0.6 0.223 -0.00362 -0.52 -0.7976 -0.9974 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J01 compound treatment 0.23 0.00363 0.5 0.23 0.00338 0.49 0.6988 0.9999 1494538 TimTec1_004071 OC1C(COC(=O)c2ccccc2)OC3C1Oc4nc(=O)ccn34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J02 compound treatment 0.247 0.0206 2.85 0.251 0.0244 3.52 4.5044 0.9945 3085226 TimTec1_004072 Cc1cc(/C=N/c2ccc(cc2)N3CCOCC3)c(C)n1c4ccc(cc4C)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J03 compound treatment 0.247 0.0206 2.85 0.251 0.0244 3.52 4.5044 0.9945 3211991 TimTec1_004073 COC(OC)C1(C)NC(=O)c2ccccc2N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J04 compound treatment 0.296 0.0696 9.62 0.297 0.0704 10.17 13.9895 0.9996 3211992 TimTec1_004074 CC1=CCC2C(C)(C)[C@@H](O)CCC2(C)C1COc3ccc4ccc(=O)oc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J05 compound treatment 0.24 0.0136 1.88 0.245 0.0184 2.65 3.2078 0.9858 3085228 TimTec1_004075 O=C(COc1ccc2ccccc2c1)Nc3ccc(Cc4ccccn4)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J06 compound treatment 0.227 6.25E-4 0.09 0.227 3.75E-4 0.05 0.0994 0.9748 3211993 TimTec1_004076 C[C@H](CSC(=O)C)C(=O)N1CCC[C@H]1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J07 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 3085230 TimTec1_004077 OCC1(CO)COC(=N1)COc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J08 compound treatment 0.23 0.00363 0.5 0.229 0.00238 0.34 0.5967 0.983 3211994 TimTec1_004078 Cc1cc(C)c(C#N)c(SCC(=O)C2CC2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J09 compound treatment 0.239 0.0126 1.74 0.233 0.00638 0.92 1.8844 0.9554 1375364 TimTec1_004079 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J10 compound treatment 0.221 -0.00537 -0.74 0.219 -0.00762 -1.1 -1.3039 -0.9816 1019637 TimTec1_004080 CN(C)c1nc2cc(Cl)ccc2o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J11 compound treatment 0.33 0.104 14.32 0.328 0.101 14.64 20.4772 0.9999 3211995 TimTec1_004081 Oc1ccc(cc1)C(=O)NN2C(SCC2=O)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J12 compound treatment 0.327 0.101 13.9 0.338 0.111 16.09 21.2055 0.9974 3211996 TimTec1_004082 COc1ccc(/C=C/2\C(=O)N(C(c3ccc(F)cc3)S2(=O)=O)c4ccc(Cl)cc4)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J13 compound treatment 0.248 0.0216 2.99 0.258 0.0314 4.53 5.3171 0.9796 1535419 TimTec1_004083 OC(COc1ccc(cc1)C(=O)c2ccccc2)CN3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J14 compound treatment 0.222 -0.00437 -0.6 0.219 -0.00762 -1.1 -1.2062 -0.9601 1646040 TimTec1_004084 CCOC(=O)C1=C(C)NC(=O)NC1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J15 compound treatment 0.228 0.00163 0.22 0.223 -0.00362 -0.52 -0.2115 -0.3713 1413879 TimTec1_004085 Ic1ccc2nc(c3ccccc3)n(NC(=S)NCC=C)c(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J16 compound treatment 0.252 0.0256 3.54 0.248 0.0214 3.09 4.6865 0.9977 1498022 TimTec1_004086 O=C1C2C(C(C=CC2c3ccccc3)c4ccccc4)C(=O)N1Cc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J17 compound treatment 0.245 0.0186 2.57 0.241 0.0144 2.08 3.2877 0.9943 1546528 TimTec1_004087 CCC(=O)N(C(=O)CC)c1cc2oc3ccccc3c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J18 compound treatment 0.382 0.156 21.5 0.319 0.0924 13.34 24.6377 0.9737 3211997 TimTec1_004088 COc1ccc(/C=N/c2nc3c(ccc4ccccc34)s2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J19 compound treatment 0.257 0.0306 4.23 0.254 0.0274 3.95 5.7877 0.9994 3085236 TimTec1_004089 OCc1coc(O)c(CN2CCCCC2)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J20 compound treatment 0.227 6.25E-4 0.09 0.228 0.00138 0.2 0.2015 0.9304 1049537 TimTec1_004090 OCCNC(=O)c1ccc(cc1)C(=O)NCCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J21 compound treatment 0.232 0.00563 0.78 0.232 0.00538 0.78 1.0985 1.0 3085238 TimTec1_004091 O=c1[nH]cnc2ccc(NC(=S)NC3CC3)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J22 compound treatment 0.229 0.00263 0.36 0.229 0.00238 0.34 0.499 0.9996 1129244 TimTec1_004092 Brc1ccc2[nH]c3C(CCCc3c2c1)NCc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J23 mock treatment 0.228 0.00163 0.22 0.229 0.00238 0.34 0.4013 0.9789 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 J24 positive control 0.228 0.00163 0.22 0.23 0.00338 0.49 0.5035 0.938 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K01 compound treatment 0.233 0.00663 0.92 0.236 0.00937 1.35 1.6047 0.9818 3085240 TimTec1_004093 Cc1ccc(Cl)c(c1)C(=O)NC2=CC(=O)CC(C)(C)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K02 compound treatment 0.241 0.0146 2.02 0.241 0.0144 2.08 2.8969 0.9999 3212056 TimTec1_004094 COC(OC)C1Nc2ccccc2C(=O)N1c3cccc(c3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K03 compound treatment 0.24 0.0136 1.88 0.25 0.0234 3.38 3.7185 0.9619 1870332 TimTec1_004095 COc1ccc(cc1)c2cc(c3ccccc3O)n(n2)C4C(=O)Nc5ccc(Br)cc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K04 compound treatment 0.222 -0.00437 -0.6 0.221 -0.00562 -0.81 -1.0019 -0.9894 3085242 TimTec1_004096 CC(C)(C)NC(=S)NCc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K05 compound treatment 0.226 -3.75E-4 -0.05 0.223 -0.00362 -0.52 -0.4069 -0.7733 1547474 TimTec1_004097 CN1CCN(CC1)C(c2ccncc2)c3ccc4cccnc4c3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K06 compound treatment 0.228 0.00163 0.22 0.227 3.75E-4 0.05 0.197 0.8532 1031437 TimTec1_004098 COc1cc(CC=C)ccc1OCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K07 compound treatment 0.225 -0.00137 -0.19 0.223 -0.00362 -0.52 -0.5046 -0.9059 3212057 TimTec1_004099 FC(F)(F)c1cccc(NC(=O)N2CCN(Cc3ccccc3)CC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K08 compound treatment 0.434 0.208 28.68 0.418 0.191 27.64 39.8291 0.9998 3085313 TimTec1_004100 O=C1CC(N(N=C1C#N)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K09 compound treatment 0.254 0.0276 3.82 0.27 0.0434 6.27 7.1289 0.9717 1194194 TimTec1_004101 O=C(CCC(=O)Nc1cccc2ccccc12)Nc3cccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K10 compound treatment 0.234 0.00763 1.05 0.23 0.00338 0.49 1.0896 0.9387 3085314 TimTec1_004102 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2C1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K11 compound treatment 0.307 0.0806 11.14 0.305 0.0784 11.32 15.8812 1.0 3212058 TimTec1_004103 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)[C@@H]4CCCC[C@@H]4C(=O)O)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K12 compound treatment 0.224 -0.00237 -0.33 0.222 -0.00462 -0.67 -0.7044 -0.9464 3212059 TimTec1_004104 Cc1cccc(OCCNC(=O)c2cccnc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K13 compound treatment 0.288 0.0616 8.51 0.286 0.0594 8.58 12.0845 1.0 1300948 TimTec1_004105 COC(=O)c1c(NC(=O)C)sc2CCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K14 compound treatment 0.221 -0.00537 -0.74 0.22 -0.00662 -0.96 -1.2017 -0.9921 3085318 TimTec1_004106 CCN(CC)C(=O)c1nn(C)c(=O)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K15 compound treatment 0.26 0.0336 4.65 0.25 0.0234 3.38 5.6722 0.9877 1423050 TimTec1_004107 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)Nc3cccc(Br)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K16 compound treatment 0.225 -0.00137 -0.19 0.222 -0.00462 -0.67 -0.6067 -0.8735 3212060 TimTec1_004108 OCCCc1nnc(SC(=O)O)n1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K17 compound treatment 0.223 -0.00337 -0.47 0.223 -0.00362 -0.52 -0.6999 -0.9983 3085320 TimTec1_004109 Cc1cc(C)n(n1)C(=O)CSc2ccc(cc2)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K18 compound treatment 0.221 -0.00537 -0.74 0.222 -0.00462 -0.67 -0.9975 -0.9986 3212061 TimTec1_004110 Fc1ccc(cc1)S(=O)(=O)Nc2nonc2NS(=O)(=O)c3ccc(F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K19 compound treatment 0.241 0.0146 2.02 0.237 0.0104 1.5 2.4884 0.9892 3085322 TimTec1_004111 CC1(C)[C@H]2CCC1(CS(=O)(=O)N(C3CCCCC3)C4CCCCC4)C(O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K20 compound treatment 0.35 0.124 17.08 0.349 0.122 17.68 24.5758 0.9999 3212062 TimTec1_004112 COC(=O)C/1=C(C)NC(=O)\C1=C/c2ccc(cc2)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K21 compound treatment 0.316 0.0896 12.38 0.306 0.0794 11.47 16.8625 0.9993 1494618 TimTec1_004113 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(C)cc4C)sc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K22 compound treatment 0.221 -0.00537 -0.74 0.222 -0.00462 -0.67 -0.9975 -0.9986 1021964 TimTec1_004114 NCCc1ccc(cc1)S(=O)(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K23 mock treatment 0.228 0.00163 0.22 0.229 0.00238 0.34 0.4013 0.9789 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 K24 positive control 0.228 0.00163 0.22 0.229 0.00238 0.34 0.4013 0.9789 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L01 compound treatment 0.254 0.0276 3.82 0.263 0.0364 5.25 6.4139 0.9877 1265817 TimTec1_004115 Cc1ccc(NC2OC(CO)C(O)C2O)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L02 compound treatment 0.222 -0.00437 -0.6 0.221 -0.00562 -0.81 -1.0019 -0.9894 3212063 TimTec1_004116 O=C(CSc1nnc(c2ccccc2)n1CCN3CCOCC3)NC4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L03 compound treatment 0.22 -0.00637 -0.88 0.22 -0.00662 -0.96 -1.2994 -0.9991 3085326 TimTec1_004117 Cc1cc(C(=O)O)c(CSCc2cc(oc2C)C(=O)O)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L04 compound treatment 0.215 -0.0114 -1.57 0.214 -0.0126 -1.82 -2.4007 -0.9973 1576521 TimTec1_004118 COc1ccc(CN(CCCN)CCC2(CC(C)N(C)CC2C)c3ccccc3)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L05 compound treatment 0.239 0.0126 1.74 0.239 0.0124 1.79 2.4973 0.9999 3212064 TimTec1_004119 CCCc1cc2OCOc2cc1NC(=O)C(C)(C)C(=O)Nc3cc4OCOc4cc3CCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L06 compound treatment 0.286 0.0596 8.24 0.307 0.0804 11.61 14.034 0.9859 3085328 TimTec1_004120 Oc1cccc(c1)c2cc(=O)c3cc(O)ccc3o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L07 compound treatment 0.22 -0.00637 -0.88 0.216 -0.0106 -1.53 -1.708 -0.9652 3085330 TimTec1_004121 Nc1cccc(c1)C2OCCCO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L08 compound treatment 0.256 0.0296 4.09 0.255 0.0284 4.1 5.7922 1.0 3212065 TimTec1_004122 Cc1cc(=O)[nH]c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L09 compound treatment 0.219 -0.00737 -1.02 0.216 -0.0106 -1.53 -1.8057 -0.9802 1408553 TimTec1_004123 CC(C)NC(=O)C(Cc1ccccc1)N2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L10 compound treatment 0.225 -0.00137 -0.19 0.223 -0.00362 -0.52 -0.5046 -0.9059 3085403 TimTec1_004124 Cc1cc2COC(=O)c2c(Sc3ccccc3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L11 compound treatment 0.247 0.0206 2.85 0.241 0.0144 2.08 3.483 0.9879 3212066 TimTec1_004125 O=C/1OC(=N\C1=C/2\OC(=O)c3ccccc23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L12 compound treatment 0.278 0.0516 7.13 0.272 0.0454 6.55 9.6777 0.9991 1563075 TimTec1_004126 O=C1CCCC2=C1C(Nc3ccc4ccccc4c23)c5cccnc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L13 compound treatment 0.346 0.12 16.53 0.333 0.106 15.37 22.5509 0.9993 3085407 TimTec1_004127 Fc1ccc(C/N=C\c2cc3ccccc3nc2Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L14 compound treatment 0.223 -0.00337 -0.47 0.22 -0.00662 -0.96 -1.0064 -0.9454 1705522 TimTec1_004128 Oc1ccc(cc1CN2CCN(CCC#N)CC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L15 compound treatment 0.284 0.0576 7.96 0.283 0.0564 8.14 11.3873 0.9999 3085409 TimTec1_004129 COc1cc(ccc1O)c2nc(S)nc(N)c2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L16 compound treatment 0.224 -0.00237 -0.33 0.219 -0.00762 -1.1 -1.0108 -0.8796 1136694 TimTec1_004130 Cc1cccc(NC(=O)CNC(=O)OCc2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L17 compound treatment 0.232 0.00563 0.78 0.229 0.00238 0.34 0.7921 0.9324 1605978 TimTec1_004131 Cn1c(=O)c(c2cc(c3ccccc3C(=O)NN)n(n2)c4ccccc4)c(O)c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L18 compound treatment 0.264 0.0376 5.2 0.265 0.0384 5.54 7.5951 0.9995 3085412 TimTec1_004132 CCOc1ccc(cc1)[C@H]2[C@@H]3CN(Cc4ccccc4)CC=C3C(=C(N)C2(C#N)C#N)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L19 compound treatment 0.223 -0.00337 -0.47 0.221 -0.00562 -0.81 -0.9042 -0.9652 3212067 TimTec1_004133 C(NC1=NC=N2CCn3cnc1c23)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L20 compound treatment 0.221 -0.00537 -0.74 0.22 -0.00662 -0.96 -1.2017 -0.9921 1912645 TimTec1_004134 CC(=O)n1nc(C)cc1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L21 compound treatment 0.216 -0.0104 -1.43 0.216 -0.0106 -1.53 -2.0987 -0.9994 3085414 TimTec1_004135 Sc1nnc(COc2ccccc2Cl)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L22 compound treatment 0.223 -0.00337 -0.47 0.223 -0.00362 -0.52 -0.6999 -0.9983 1409212 TimTec1_004136 COc1ccccc1CNC(=O)COc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L23 mock treatment 0.228 0.00163 0.22 0.229 0.00238 0.34 0.4013 0.9789 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 L24 positive control 0.226 -3.75E-4 -0.05 0.226 -6.25E-4 -0.09 -0.1005 -0.9652 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M01 compound treatment 0.232 0.00563 0.78 0.231 0.00438 0.63 0.9963 0.9947 1608236 TimTec1_004137 CC(C)c1ccc(cc1)c2csc3ncn(N)c(=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M02 compound treatment 0.228 0.00163 0.22 0.228 0.00138 0.2 0.2992 0.9981 3212068 TimTec1_004138 Cn1c(=O)n(C)c2cc(CN3C(=O)c4ccccc4C3=O)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M03 compound treatment 0.228 0.00163 0.22 0.231 0.00438 0.63 0.6056 0.903 1233601 TimTec1_004139 Cc1nn(c2CC(CC(=O)c12)c3ccco3)c4ccccn4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M04 compound treatment 0.292 0.0656 9.07 0.315 0.0884 12.77 15.4372 0.9859 1300398 TimTec1_004140 O=C(NC1CC1)c2ccc(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M05 compound treatment 0.232 0.00563 0.78 0.24 0.0134 1.93 1.9156 0.9199 1190193 TimTec1_004141 Cc1[nH]c2ccccc2c1C(N3CCN(CC3)c4ccccc4)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M06 compound treatment 0.224 -0.00237 -0.33 0.22 -0.00662 -0.96 -0.9087 -0.8982 1227000 TimTec1_004142 NNc1ccc2[nH]c(=O)[nH]c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M07 compound treatment 0.224 -0.00237 -0.33 0.219 -0.00762 -1.1 -1.0108 -0.8796 1560140 TimTec1_004143 Fc1ccc(Cn2cnc3ccccc3c2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M08 compound treatment 0.227 6.25E-4 0.09 0.224 -0.00262 -0.38 -0.2071 -0.5325 3212133 TimTec1_004144 CC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M09 compound treatment 0.23 0.00363 0.5 0.228 0.00138 0.2 0.4946 0.918 3085420 TimTec1_004145 Brc1ccc(o1)C(=O)Nc2ccc(C#N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M10 compound treatment 0.217 -0.00937 -1.3 0.215 -0.0116 -1.68 -2.1032 -0.9918 3212134 TimTec1_004146 CCC1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(OC)c(OC)cc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M11 compound treatment 0.22 -0.00637 -0.88 0.219 -0.00762 -1.1 -1.4016 -0.9939 3085422 TimTec1_004147 C[C@@H]1CC2(CCCN2Cc3ccccc3)C[C@H]1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M12 compound treatment 0.217 -0.00937 -1.3 0.215 -0.0116 -1.68 -2.1032 -0.9918 3085423 TimTec1_004148 O=C(NCCN1CCN=C1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M13 compound treatment 0.225 -0.00137 -0.19 0.223 -0.00362 -0.52 -0.5046 -0.9059 1325497 TimTec1_004149 CCC(=O)Nc1ccccc1C(=O)Nc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M14 compound treatment 0.311 0.0846 11.69 0.316 0.0894 12.91 17.3954 0.9988 3085425 TimTec1_004150 O=c1cc(CSc2nc3ccccc3s2)c4ccccc4[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M15 compound treatment 0.218 -0.00837 -1.16 0.214 -0.0126 -1.82 -2.1076 -0.9759 1732529 TimTec1_004151 CC(C)NS(=O)(=O)c1ccc(NC(=O)C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M16 compound treatment 0.229 0.00263 0.36 0.225 -0.00162 -0.23 0.0905 0.2094 1321742 TimTec1_004152 CC(C)(C)NC(=O)CSc1nc2ccccc2n1c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M17 compound treatment 0.224 -0.00237 -0.33 0.221 -0.00562 -0.81 -0.8065 -0.9204 3212135 TimTec1_004153 O=S(=O)(NCCCn1ccnc1)c2ccc3ccccc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M18 compound treatment 0.257 0.0306 4.23 0.254 0.0274 3.95 5.7877 0.9994 3084387 TimTec1_004154 Cc1ccc(cc1S(=O)(=O)NC(C)(C)CO)c2nnc(N3CCOCC3)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M19 compound treatment 0.226 -3.75E-4 -0.05 0.225 -0.00162 -0.23 -0.2026 -0.8429 1026799 TimTec1_004155 OC(=O)c1ccc(Br)c(c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M20 compound treatment 0.25 0.0236 3.26 0.25 0.0234 3.38 4.6954 0.9999 3212136 TimTec1_004156 OC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M21 compound treatment 0.224 -0.00237 -0.33 0.225 -0.00162 -0.23 -0.398 -0.9865 3084389 TimTec1_004157 COc1ccc(cc1)C2CC(=O)Nc3cc4OCOc4cc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M22 compound treatment 0.221 -0.00537 -0.74 0.221 -0.00562 -0.81 -1.0996 -0.999 3069528 TimTec1_004158 C/C=C\1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M23 mock treatment 0.227 6.25E-4 0.09 0.227 3.75E-4 0.05 0.0994 0.9748 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 M24 positive control 0.225 -0.00137 -0.19 0.225 -0.00162 -0.23 -0.3003 -0.9945 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N01 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 3212137 TimTec1_004159 OCC1OC(CC1O)Nc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N02 compound treatment 0.309 0.0826 11.41 0.347 0.12 17.39 20.3664 0.9792 3212138 TimTec1_004160 CC/1=NNC(=O)\C1=C/c2cn(nc2c3ccc(F)cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N03 compound treatment 0.22 -0.00637 -0.88 0.218 -0.00862 -1.25 -1.5037 -0.9856 3084392 TimTec1_004161 Cn1cnnc1c2ccc(N)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N04 compound treatment 0.219 -0.00737 -1.02 0.216 -0.0106 -1.53 -1.8057 -0.9802 3084393 TimTec1_004162 CN(Cc1ccccc1)C(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N05 compound treatment 0.228 0.00163 0.22 0.223 -0.00362 -0.52 -0.2115 -0.3713 3212139 TimTec1_004163 Cc1nc2ccc(NC(=O)C(C)(C)C(=O)Nc3ccc4nc(C)c(C)nc4c3)cc2nc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N06 compound treatment 0.224 -0.00237 -0.33 0.222 -0.00462 -0.67 -0.7044 -0.9464 3084395 TimTec1_004164 Cc1ccccc1OCc2nnc(S)n2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N07 compound treatment 0.388 0.162 22.33 0.397 0.17 24.61 33.1906 0.9988 3212140 TimTec1_004165 O=C(/C=C/c1cccs1)C(=C2SCCCCS2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N08 compound treatment 0.226 -3.75E-4 -0.05 0.221 -0.00562 -0.81 -0.6112 -0.7507 1485279 TimTec1_004166 CCOC(=O)C1=C(C)NC2(O)CC1C3COC2O3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N09 compound treatment 0.216 -0.0104 -1.43 0.214 -0.0126 -1.82 -2.303 -0.9929 1264107 TimTec1_004167 Cc1ccc(cc1)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N10 compound treatment 0.222 -0.00437 -0.6 0.224 -0.00262 -0.38 -0.6955 -0.9748 1616817 TimTec1_004168 CCc1nc(SCC(=O)C(C)(C)C)c(C#N)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N11 compound treatment 0.217 -0.00937 -1.3 0.213 -0.0136 -1.97 -2.3075 -0.9794 1253074 TimTec1_004169 O=C(NC(=S)NCc1ccco1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N12 compound treatment 0.348 0.122 16.8 0.329 0.102 14.79 22.3377 0.998 3084399 TimTec1_004170 Cc1[nH]c2ccccc2c1/C=N/c3c(nc4ccccn34)c5ccco5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N13 compound treatment 0.224 -0.00237 -0.33 0.222 -0.00462 -0.67 -0.7044 -0.9464 1017704 TimTec1_004171 Nc1ncnc2[nH]c(nc12)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N14 compound treatment 0.238 0.0116 1.61 0.231 0.00438 0.63 1.5825 0.9169 3212141 TimTec1_004172 CCOC(=O)c1sc(SC#N)c(c1N)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N15 compound treatment 0.224 -0.00237 -0.33 0.219 -0.00762 -1.1 -1.0108 -0.8796 1004708 TimTec1_004173 COc1ccccc1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N16 compound treatment 0.223 -0.00337 -0.47 0.221 -0.00562 -0.81 -0.9042 -0.9652 1222145 TimTec1_004174 CC(C)N1CC(COc2ccccc2)OC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N17 compound treatment 0.24 0.0136 1.88 0.231 0.00438 0.63 1.7779 0.8954 3084402 TimTec1_004175 Cc1cc(N)n(n1)c2ncnc3sc4CCCCc4c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N18 compound treatment 0.246 0.0196 2.71 0.243 0.0164 2.37 3.5896 0.9977 1166305 TimTec1_004176 Cc1ccc(cc1S)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N19 compound treatment 0.289 0.0626 8.65 0.277 0.0504 7.28 11.2629 0.9963 3212142 TimTec1_004177 Cc1nc2ccccc2nc1N/C(=N/C(=O)c3ccccc3)/N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N20 compound treatment 0.242 0.0156 2.16 0.233 0.00638 0.92 2.1775 0.9279 1378550 TimTec1_004178 O=C1CCC(=O)N1CNc2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N21 compound treatment 0.278 0.0516 7.13 0.273 0.0464 6.7 9.7798 0.9995 3212143 TimTec1_004179 Cc1nc2ccc(NC(=O)N3CC4(C)CC3CC(C)(C)C4)cc2nc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N22 compound treatment 0.253 0.0266 3.68 0.252 0.0254 3.67 5.1927 1.0 1205779 TimTec1_004180 NC(=O)c1cc2ccccc2oc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N23 mock treatment 0.224 -0.00237 -0.33 0.226 -6.25E-4 -0.09 -0.2958 -0.8694 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 N24 positive control 0.224 -0.00237 -0.33 0.225 -0.00162 -0.23 -0.398 -0.9865 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O01 compound treatment 0.225 -0.00137 -0.19 0.226 -6.25E-4 -0.09 -0.1982 -0.9422 1144219 TimTec1_004181 Cc1sc2ncnc(N3CCN(Cc4ccccc4)CC3)c2c1c5ccc(F)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O02 compound treatment 0.218 -0.00837 -1.16 0.217 -0.00962 -1.39 -1.8012 -0.9958 3084915 TimTec1_004182 COc1ccc(cc1OC)c2nnc(SC)n2CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O03 compound treatment 0.215 -0.0114 -1.57 0.213 -0.0136 -1.97 -2.5028 -0.9938 1582942 TimTec1_004183 CC1=CCC(C(C1)c2ccc(Br)cc2)(C(=O)O)C(=O)NCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O04 compound treatment 0.221 -0.00537 -0.74 0.218 -0.00862 -1.25 -1.406 -0.9694 1277662 TimTec1_004184 COc1ccc(cc1)C(=O)NC2CCCCC2NC(=O)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O05 compound treatment 0.248 0.0216 2.99 0.26 0.0334 4.82 5.5214 0.9735 1305407 TimTec1_004185 Fc1ccc(cc1)c2csc3ncnc(Oc4ccc5ccc(=O)oc5c4)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O06 compound treatment 0.221 -0.00537 -0.74 0.219 -0.00762 -1.1 -1.3039 -0.9816 3212144 TimTec1_004186 OC(=O)c1cc(ccc1Cl)N2N=C(/C(=C/c3ccc(o3)c4ccccc4)/C2=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O07 compound treatment 0.22 -0.00637 -0.88 0.216 -0.0106 -1.53 -1.708 -0.9652 3084918 TimTec1_004187 COC(=O)c1nn(c(Br)c1C(=O)OC)c2ccc(Br)cc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O08 compound treatment 0.223 -0.00337 -0.47 0.215 -0.0116 -1.68 -1.5171 -0.8705 3084920 TimTec1_004188 COc1cc(Br)c(CN(CCc2ccc(O)cc2)C(=O)C(F)(F)F)cc1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O09 compound treatment 0.23 0.00363 0.5 0.227 3.75E-4 0.05 0.3924 0.779 1388832 TimTec1_004189 Clc1ccccc1C(=O)NC2CCCCC2NC(=O)c3ccccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O10 compound treatment 0.261 0.0346 4.78 0.261 0.0344 4.97 6.8934 0.9998 1535096 TimTec1_004190 CC(C)c1ccc(cc1)C2C(=C(N)Oc3c2n(C(=O)C)c4ccccc34)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O11 compound treatment 0.28 0.0536 7.41 0.241 0.0144 2.08 6.7067 0.8717 1851014 TimTec1_004191 COc1ccc2c(Cl)c(sc2c1)C(=O)Oc3ccccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O12 compound treatment 0.245 0.0186 2.57 0.264 0.0374 5.4 5.6369 0.9425 1407017 TimTec1_004192 CCN(CC)c1ccc2c(c1)oc(=O)c3c(Cl)cc(=O)oc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O13 compound treatment 0.226 -3.75E-4 -0.05 0.225 -0.00162 -0.23 -0.2026 -0.8429 1440352 TimTec1_004193 OC(=O)c1ccccc1C(=O)N2CCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O14 compound treatment 0.222 -0.00437 -0.6 0.219 -0.00762 -1.1 -1.2062 -0.9601 3084985 TimTec1_004194 COC(=O)Nc1ncc(CN2CCC(C)CC2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O15 compound treatment 0.274 0.0476 6.58 0.265 0.0384 5.54 8.5719 0.9964 1441746 TimTec1_004195 O=C(Cc1ccccc1)NN(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O16 compound treatment 0.316 0.0896 12.38 0.325 0.0984 14.21 18.8031 0.9976 1247973 TimTec1_004196 CC1CCCCN1C(=O)c2ccccc2NS(=O)(=O)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O17 compound treatment 0.217 -0.00937 -1.3 0.215 -0.0116 -1.68 -2.1032 -0.9918 3084989 TimTec1_004197 CCOCC(O)CSc1nc(C)cc(C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O18 compound treatment 0.222 -0.00437 -0.6 0.22 -0.00662 -0.96 -1.1041 -0.9754 1089162 TimTec1_004198 OCC1OC(C(O)C1O)n2ccc(NC(=O)c3ccccc3)nc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O19 compound treatment 0.22 -0.00637 -0.88 0.22 -0.00662 -0.96 -1.2994 -0.9991 3084991 TimTec1_004199 CC1(C)[C@H]2CCC1(CS(=O)(=O)N)C(=O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O20 compound treatment 0.39 0.164 22.6 0.371 0.144 20.85 30.7304 0.9992 3212307 TimTec1_004200 OC(=O)c1cc(cc(c1)c2ccc(/C=N\c3ccc4[nH]c(=O)[nH]c4c3)o2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O21 compound treatment 0.219 -0.00737 -1.02 0.219 -0.00762 -1.1 -1.4993 -0.9992 3084993 TimTec1_004201 Clc1ccc(cc1)C2NC(=O)NC(=C2)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O22 compound treatment 0.217 -0.00937 -1.3 0.217 -0.00962 -1.39 -1.8989 -0.9994 1067834 TimTec1_004202 NCCC(c1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O23 mock treatment 0.223 -0.00337 -0.47 0.223 -0.00362 -0.52 -0.6999 -0.9983 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 O24 positive control 0.219 -0.00737 -1.02 0.219 -0.00762 -1.1 -1.4993 -0.9992 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P01 compound treatment 0.225 -0.00137 -0.19 0.224 -0.00262 -0.38 -0.4024 -0.9489 3212216 TimTec1_004203 CC(C)(C)C1(O)CC2OC(=O)CC23C(=O)OC4OC(=O)C(O)C413 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P02 compound treatment 0.239 0.0126 1.74 0.238 0.0114 1.64 2.3951 0.9996 1735319 TimTec1_004204 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=N)c3c(N)c(C#N)c(N)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P03 compound treatment 0.228 0.00163 0.22 0.225 -0.00162 -0.23 -0.0072 -0.0223 3212217 TimTec1_004205 COc1cc2C[C@@H]3N(C)CCc4c(N)c(OC)c(OC)c(-c2cc1OC)c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P04 compound treatment 0.283 0.0566 7.82 0.332 0.105 15.22 16.2944 0.9521 3084996 TimTec1_004206 Oc1ccc2cc(c3cccc(Br)c3)c(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P05 compound treatment 0.288 0.0616 8.51 0.293 0.0664 9.59 12.7994 0.9982 3212218 TimTec1_004207 Cc1ccc(cc1Cl)C(=O)NC2CS(=O)(=O)CC2NC(=O)c3ccc(C)c(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P06 compound treatment 0.224 -0.00237 -0.33 0.223 -0.00362 -0.52 -0.6023 -0.9747 1055533 TimTec1_004208 NC(=O)c1c(F)c(F)c(N)c(F)c1F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P07 compound treatment 0.371 0.145 19.98 0.353 0.126 18.25 27.0358 0.999 3212219 TimTec1_004209 OC1=CC(O)(N(/N=C/2\C(=O)Nc3ccc(Br)cc23)C1=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P08 compound treatment 0.227 6.25E-4 0.09 0.219 -0.00762 -1.1 -0.7178 -0.6497 3084999 TimTec1_004210 CC/C(=N/O)/C(=O)c1ccc(Br)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P09 compound treatment 0.232 0.00563 0.78 0.223 -0.00362 -0.52 0.1792 0.1913 1118292 TimTec1_004211 COc1ccc(NC(=O)CC(=O)c2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P10 compound treatment 0.217 -0.00937 -1.3 0.215 -0.0116 -1.68 -2.1032 -0.9918 3212220 TimTec1_004212 CC1(C)N2CN(CCCCN3CN4N(C3)C4(C)C)CN21 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P11 compound treatment 0.216 -0.0104 -1.43 0.213 -0.0136 -1.97 -2.4051 -0.9879 3085001 TimTec1_004213 FC(F)(F)c1ccccc1NCn2nnc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P12 compound treatment 0.269 0.0426 5.89 0.27 0.0434 6.27 8.5942 0.9995 1471541 TimTec1_004214 OC(=O)CCNc1ccc(Br)cc1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P13 compound treatment 0.219 -0.00737 -1.02 0.219 -0.00762 -1.1 -1.4993 -0.9992 3212221 TimTec1_004215 CCOC(=O)c1[nH]c(=O)[nH]c1CC2C(=O)CC(C)(C)CC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P14 compound treatment 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 1913403 TimTec1_004216 CN(C)c1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P15 compound treatment 0.277 0.0506 6.99 0.275 0.0484 6.99 9.8864 1.0 1008937 TimTec1_004217 C(COc1ccccc1)Oc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P16 compound treatment 0.224 -0.00237 -0.33 0.219 -0.00762 -1.1 -1.0108 -0.8796 1247888 TimTec1_004218 O=C(CSc1ccccn1)NCC(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P17 compound treatment 0.269 0.0426 5.89 0.255 0.0284 4.1 7.0621 0.9843 1266971 TimTec1_004219 C(Sc1nc2ccccc2o1)c3cccc(Oc4ccccc4)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P18 compound treatment 0.223 -0.00337 -0.47 0.222 -0.00462 -0.67 -0.8021 -0.9845 3212222 TimTec1_004220 Cc1nnc(SCc2ccc(F)cc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P19 compound treatment 0.223 -0.00337 -0.47 0.217 -0.00962 -1.39 -1.3128 -0.8952 1377201 TimTec1_004221 O=C1N(CCNS(=O)(=O)c2ccc3oc4ccccc4c3c2)Cc5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P20 compound treatment 0.243 0.0166 2.3 0.237 0.0104 1.5 2.6837 0.9786 1474244 TimTec1_004222 CC1(C)Cc2c(CO1)c(nc3sc(cc23)C(=O)O)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P21 compound treatment 0.249 0.0226 3.13 0.25 0.0234 3.38 4.5977 0.9993 3212223 TimTec1_004223 COc1cccc2C(CC(=O)c3ccc(O)cc3)C4=C(CC(C)(C)CC4=O)Oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P22 compound treatment 0.218 -0.00837 -1.16 0.216 -0.0106 -1.53 -1.9034 -0.9903 3085007 TimTec1_004224 CC(=CCS(=O)(=O)c1ccccc1)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P23 mock treatment 0.227 6.25E-4 0.09 0.224 -0.00262 -0.38 -0.2071 -0.5325 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2074 P24 positive control 0.222 -0.00437 -0.6 0.222 -0.00462 -0.67 -0.8998 -0.9988 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A01 compound treatment 0.213 -0.0166 -2.3 0.209 -0.0163 -2.36 -3.2902 -0.9999 3212900 TimTec1_004577 Cc1n[nH]c(O)c1CCCOc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A02 compound treatment 0.225 -0.00462 -0.64 0.221 -0.00431 -0.62 -0.8923 -0.9999 3085778 TimTec1_004578 Cc1cc(Sc2ccccn2)c3ccccc3n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A03 compound treatment 0.219 -0.0106 -1.47 0.208 -0.0173 -2.5 -2.8062 -0.9678 3212901 TimTec1_004579 [O-][n+]1onc2c(nnc(c3ccc(Cl)cc3)c12)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A04 compound treatment 0.21 -0.0196 -2.71 0.201 -0.0243 -3.51 -4.4004 -0.9918 3085779 TimTec1_004580 NC(=O)CSc1nc(N)cc(N)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A05 compound treatment 0.217 -0.0126 -1.74 0.211 -0.0143 -2.07 -2.6952 -0.9964 3212902 TimTec1_004581 Cc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCN(CC4)c5ccccc5)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A06 compound treatment 0.228 -0.00162 -0.22 0.224 -0.00131 -0.19 -0.2928 -0.9965 3085780 TimTec1_004582 COc1ccc(cc1OC)C2C(C(=O)NC(=C2C#N)O)[n+]3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A07 compound treatment 0.217 -0.0126 -1.74 0.206 -0.0193 -2.79 -3.2059 -0.9744 3211405 TimTec1_004583 CN1C(=O)CCN(C=O)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A08 compound treatment 0.211 -0.0186 -2.57 0.208 -0.0173 -2.5 -3.5877 -0.9999 1392481 TimTec1_004584 CCC(=O)Nc1c(C)c(Cl)c(C)nc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A09 compound treatment 0.213 -0.0166 -2.3 0.212 -0.0133 -1.92 -2.9838 -0.9961 3211202 TimTec1_004585 CC(=O)NC1C(=O)NC(=NC1=O)SCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A10 compound treatment 0.337 0.107 14.83 0.338 0.113 16.28 21.9989 0.9989 1665015 TimTec1_004586 OC1=C(C(=O)c2ccccc2)C3(OC1=O)C(=O)NC(=O)NC3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A11 compound treatment 0.211 -0.0186 -2.57 0.209 -0.0163 -2.36 -3.4856 -0.999 1224645 TimTec1_004587 COc1ccc(NC(=S)N(CC2CCCO2)CC3CCC=CC3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A12 compound treatment 0.22 -0.00962 -1.33 0.216 -0.00931 -1.35 -1.8914 -1.0 1534543 TimTec1_004588 Cc1nc(C(=O)N)c(N)n1CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A13 compound treatment 0.23 3.75E-4 0.05 0.223 -0.00231 -0.33 -0.1996 -0.5904 3211203 TimTec1_004589 OC(=O)C1CCCCC1C(=O)Nc2ccc3[nH]c(=S)sc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A14 compound treatment 0.209 -0.0206 -2.85 0.208 -0.0173 -2.5 -3.7831 -0.9979 1303334 TimTec1_004590 CCC1(C)OC(=O)N(CCc2c(C)[nH]c3ccccc23)C1(C)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A15 compound treatment 0.208 -0.0216 -2.99 0.208 -0.0173 -2.5 -3.8808 -0.9961 1738265 TimTec1_004591 CC1(C)CC(CC(C)(C)N1)N2C(=O)c3ccccc3C2(O)Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A16 compound treatment 0.252 0.0224 3.09 0.26 0.0347 5.01 5.7287 0.9731 1544216 TimTec1_004592 O=C1Nc2nonc2NC(=C1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A17 compound treatment 0.212 -0.0176 -2.43 0.208 -0.0173 -2.5 -3.49 -0.9999 1580828 TimTec1_004593 OCC1COC(=O)N1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A18 compound treatment 0.214 -0.0156 -2.16 0.212 -0.0133 -1.92 -2.8861 -0.9983 3211204 TimTec1_004594 CN1CCN(CC1)n/2c(cs\c2=N/c3ccccc3)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A19 compound treatment 0.358 0.128 17.74 0.359 0.134 19.31 26.1953 0.9991 3085781 TimTec1_004595 CCCn1c2ccccc2c3nnc(SCCNS(=O)(=O)c4ccccc4)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A20 compound treatment 0.215 -0.0146 -2.02 0.213 -0.0123 -1.78 -2.6863 -0.998 1295244 TimTec1_004596 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A21 compound treatment 0.208 -0.0216 -2.99 0.21 -0.0153 -2.21 -3.6765 -0.9891 1339032 TimTec1_004597 O=S1(=O)N=C(Oc2ccccc2)c3ccccc31 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A22 compound treatment 0.211 -0.0186 -2.57 0.211 -0.0143 -2.07 -3.2813 -0.9941 3211205 TimTec1_004598 COc1ccc(cc1)n2c(=O)c3c4CC(OCc4sc3n5cnnc25)C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A23 mock treatment 0.222 -0.00762 -1.05 0.217 -0.00831 -1.2 -1.5939 -0.9979 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 A24 positive control 0.216 -0.0136 -1.88 0.212 -0.0133 -1.92 -2.6907 -0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B01 compound treatment 0.251 0.0214 2.95 0.247 0.0217 3.13 4.3032 0.9996 1180956 TimTec1_004599 CC(=O)Nc1cccc(C(=O)Oc2cccc(C)c2)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B02 compound treatment 0.256 0.0264 3.64 0.248 0.0227 3.28 4.8938 0.9986 3211206 TimTec1_004600 CC(C)OC(=O)COc1ccc2C(CC3(CC(C)(C)NC(=O)N3)Oc2c1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B03 compound treatment 0.266 0.0364 5.03 0.253 0.0277 4.0 6.3813 0.9936 3085782 TimTec1_004601 O=S1(=O)N(Cc2ccccn2)c3cccc4cccc1c34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B04 compound treatment 0.303 0.0734 10.14 0.295 0.0697 10.07 14.2856 1.0 3211207 TimTec1_004602 Cc1nn(c(N)c1c2ccc(Cl)cc2)c3nc4ccccc4[nH]3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B05 compound treatment 0.264 0.0344 4.75 0.257 0.0317 4.58 6.5945 0.9998 3085783 TimTec1_004603 OC1COC(NCCc2ccccc2)C(O)C1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B06 compound treatment 0.315 0.0854 11.79 0.313 0.0877 12.67 17.2963 0.9994 1409204 TimTec1_004604 N(c1ccccc1)c2nc3nonc3nc2Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B07 compound treatment 0.364 0.134 18.56 0.369 0.144 20.76 27.8028 0.9985 3211208 TimTec1_004605 FC(F)(F)C1(N=C(Nc2c1c(=O)[nH]c(=O)n2c3ccccc3)c4ccncc4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B08 compound treatment 0.233 0.00338 0.47 0.226 6.88E-4 0.1 0.3999 0.8389 3085788 TimTec1_004606 CN1C2NCN(CCc3ccccc3)CC2C(=O)N(C)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B09 compound treatment 0.254 0.0244 3.37 0.255 0.0297 4.29 5.4134 0.9928 3211209 TimTec1_004607 CCOc1ccc(Cn2nnc(n2)c3ccc(cc3)S(=O)(=O)C)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B10 compound treatment 0.344 0.114 15.8 0.343 0.118 17.0 23.1934 0.9993 1264288 TimTec1_004608 CN(NC1=C(C)CN(C2CCCCC2)C1=O)c3cccc(Cl)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B11 compound treatment 0.227 -0.00262 -0.36 0.221 -0.00431 -0.62 -0.6969 -0.9669 3211210 TimTec1_004609 OCC1OC(C(O)C1O)n2ccc(O)nc2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B12 compound treatment 0.239 0.00937 1.3 0.233 0.00769 1.11 1.701 0.9971 1629862 TimTec1_004610 OC1=C(Cc2ccccc2)CN(Cc3ccccc3)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B13 compound treatment 0.31 0.0804 11.1 0.31 0.0847 12.23 16.5015 0.9988 3211211 TimTec1_004611 CCCCc1ccc2nc3sc(cc3cc2c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B14 compound treatment 0.225 -0.00462 -0.64 0.216 -0.00931 -1.35 -1.403 -0.9421 3085792 TimTec1_004612 CC1(C)CC(=O)OC(C1)(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B15 compound treatment 0.225 -0.00462 -0.64 0.219 -0.00631 -0.91 -1.0966 -0.9849 3211212 TimTec1_004613 CCCCS(=O)(=O)Nc1ccc(Cc2ccncc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B16 compound treatment 0.229 -6.25E-4 -0.09 0.219 -0.00631 -0.91 -0.7058 -0.7706 3211213 TimTec1_004614 FC(F)(F)C(=O)Nc1ccccc1C(=O)NCc2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B17 compound treatment 0.253 0.0234 3.23 0.253 0.0277 4.0 5.1114 0.9944 3085794 TimTec1_004615 CC(C)Nc1nc(nc(n1)n2ccnc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B18 compound treatment 0.229 -6.25E-4 -0.09 0.22 -0.00531 -0.77 -0.6037 -0.7817 3085836 TimTec1_004616 O=CN1CCN(CC1)C(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B19 compound treatment 0.237 0.00737 1.02 0.222 -0.00331 -0.48 0.3821 0.3395 3085838 TimTec1_004617 N(c1cccc2ccccc12)c3nc(nc(n3)n4ccnc4)n5ccnc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B20 compound treatment 0.251 0.0214 2.95 0.246 0.0207 2.99 4.2011 1.0 1599768 TimTec1_004618 COC(=O)C1C(c2cc(OC)c(OC)cc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B21 compound treatment 0.224 -0.00562 -0.78 0.22 -0.00531 -0.77 -1.0921 -1.0 3085840 TimTec1_004619 CC(C)(O)c1nnn(Cc2ccccc2)c1C(C)(C)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B22 compound treatment 0.271 0.0414 5.72 0.262 0.0367 5.3 7.789 0.9993 1176863 TimTec1_004620 Cc1ncsc1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B23 mock treatment 0.235 0.00537 0.74 0.224 -0.00131 -0.19 0.391 0.5102 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 B24 positive control 0.232 0.00238 0.33 0.223 -0.00231 -0.33 -0.0042 -0.0089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C01 compound treatment 0.25 0.0204 2.81 0.246 0.0207 2.99 4.1034 0.9996 3085842 TimTec1_004621 O=C(N/C(=C(\Sc1ccccn1)/c2ccccc2)/C(=O)N3CCOCC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C02 compound treatment 0.232 0.00238 0.33 0.219 -0.00631 -0.91 -0.4127 -0.4259 3211214 TimTec1_004622 N#Cc1ccc(CSc2ncccn2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C03 compound treatment 0.228 -0.00162 -0.22 0.223 -0.00231 -0.33 -0.3949 -0.9813 1239016 TimTec1_004623 COc1ccc(C(=O)Nc2ccncc2)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C04 compound treatment 0.255 0.0254 3.51 0.244 0.0187 2.7 4.3875 0.9917 1306638 TimTec1_004624 COc1ccc(cc1OC)C(=O)CSC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C05 compound treatment 0.224 -0.00562 -0.78 0.213 -0.0123 -1.78 -1.8071 -0.9311 3085845 TimTec1_004625 CN1C(OC(=O)C)C(OC(=O)C)N(C)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C06 compound treatment 0.228 -0.00162 -0.22 0.22 -0.00531 -0.77 -0.7014 -0.8772 1689037 TimTec1_004626 CC(=O)Nc1ccc(cc1)C2N3CCCN23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C07 compound treatment 0.232 0.00238 0.33 0.224 -0.00131 -0.19 0.098 0.2585 1384622 TimTec1_004627 C=CCN1C(=O)CCNc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C08 compound treatment 0.232 0.00238 0.33 0.224 -0.00131 -0.19 0.098 0.2585 1104469 TimTec1_004628 Cc1cc(Cl)nc(Cl)c1C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C09 compound treatment 0.227 -0.00262 -0.36 0.219 -0.00631 -0.91 -0.9012 -0.9184 1540410 TimTec1_004629 Brc1ccc(o1)C(=O)NC2C3CC4CC(C3)CC2C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C10 compound treatment 0.219 -0.0106 -1.47 0.217 -0.00831 -1.2 -1.887 -0.995 3085848 TimTec1_004630 C1CCN2C(C3N4CCCCN34)N2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C11 compound treatment 0.222 -0.00762 -1.05 0.217 -0.00831 -1.2 -1.5939 -0.9979 1554188 TimTec1_004631 CCOC(=O)C1(CCN(CCOc2ccccc2)CC1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C12 compound treatment 0.231 0.00138 0.19 0.232 0.00669 0.97 0.8174 0.8303 1287126 TimTec1_004632 O=S(Cc1ccccc1)c2cc(Oc3ccccc3)ccc2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C13 compound treatment 0.239 0.00937 1.3 0.236 0.0107 1.54 2.0074 0.9962 3211215 TimTec1_004633 O=C/1N2C(=C\C1=C/N3CCCCC3)C(=O)c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C14 compound treatment 0.224 -0.00562 -0.78 0.222 -0.00331 -0.48 -0.8878 -0.9729 1182870 TimTec1_004634 CCCc1cc2c3ccccc3oc(=O)c2c(NC(=O)C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C15 compound treatment 0.223 -0.00662 -0.92 0.219 -0.00631 -0.91 -1.2919 -1.0 1129282 TimTec1_004635 OC(=O)C1CC(=O)CCC1Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C16 compound treatment 0.23 3.75E-4 0.05 0.223 -0.00231 -0.33 -0.1996 -0.5904 1342925 TimTec1_004636 COc1nc(Cl)nc(n1)N2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C17 compound treatment 0.233 0.00338 0.47 0.227 0.00169 0.24 0.5021 0.9542 3211216 TimTec1_004637 OC(=O)c1ccc(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C18 compound treatment 0.239 0.00937 1.3 0.233 0.00769 1.11 1.701 0.9971 1658196 TimTec1_004638 CCCCc1c(C)nc2ccc(Br)cc2c1SCCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C19 compound treatment 0.226 -0.00362 -0.5 0.224 -0.00131 -0.19 -0.4882 -0.9117 1175416 TimTec1_004639 CC(=O)NC(C)(C)COc1ccc(Cl)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C20 compound treatment 0.223 -0.00662 -0.92 0.218 -0.00731 -1.06 -1.3941 -0.9975 1184099 TimTec1_004640 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cc[nH]n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C21 compound treatment 0.226 -0.00362 -0.5 0.22 -0.00531 -0.77 -0.8967 -0.9786 3085855 TimTec1_004641 CC1=CC(C)(C)NC(=S)N1CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C22 compound treatment 0.259 0.0294 4.06 0.256 0.0307 4.43 6.0039 0.999 1171271 TimTec1_004642 O=C(NN1C(=O)c2ccccc2NC31CCCC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C23 mock treatment 0.232 0.00238 0.33 0.225 -3.12E-4 -0.05 0.2001 0.6041 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 C24 positive control 0.233 0.00338 0.47 0.226 6.88E-4 0.1 0.3999 0.8389 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D01 compound treatment 0.224 -0.00562 -0.78 0.222 -0.00331 -0.48 -0.8878 -0.9729 1550109 TimTec1_004643 Cc1oc(C)c(C(=O)O)c1CN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D02 compound treatment 0.231 0.00138 0.19 0.227 0.00169 0.24 0.3067 0.9924 3085895 TimTec1_004644 Clc1ccc2oc3c(=O)oc(nc3c2c1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D03 compound treatment 0.223 -0.00662 -0.92 0.218 -0.00731 -1.06 -1.3941 -0.9975 3211406 TimTec1_004645 O=C(NC(=O)c1ccccc1)OC2CCS(=O)(=O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D04 compound treatment 0.218 -0.0116 -1.61 0.22 -0.00531 -0.77 -1.6782 -0.9429 3211407 TimTec1_004646 OC(=O)CC(NC(=O)C1(CC2CC3CC(C2)C1)C3)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D05 compound treatment 0.221 -0.00862 -1.19 0.216 -0.00931 -1.35 -1.7937 -0.9982 3085898 TimTec1_004647 CN(C1CC(C)(C)NC(C)(C)C1)C(=O)c2ccccc2C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D06 compound treatment 0.228 -0.00162 -0.22 0.223 -0.00231 -0.33 -0.3949 -0.9813 1913187 TimTec1_004648 CSc1sc(SC)c(C[n+]2ccccc2)c1C[n+]3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D07 compound treatment 0.241 0.0114 1.57 0.24 0.0147 2.12 2.6114 0.9891 3085900 TimTec1_004649 Cc1cc(NC(=O)NC(=O)c2cccs2)n[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D08 compound treatment 0.225 -0.00462 -0.64 0.223 -0.00231 -0.33 -0.688 -0.9542 1392952 TimTec1_004650 COc1ccc(cc1)N2CC(CC2=O)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D09 compound treatment 0.223 -0.00662 -0.92 0.213 -0.0123 -1.78 -1.9048 -0.9523 3211408 TimTec1_004651 Cc1cn(CC(=O)NCCN)c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D10 compound treatment 0.256 0.0264 3.64 0.271 0.0457 6.6 7.243 0.9608 1692385 TimTec1_004652 CN(Nc1ccccc1)C2=C(CN(C3CCCCC3)C2=O)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D11 compound treatment 0.341 0.111 15.39 0.348 0.123 17.72 23.4111 0.9975 3211409 TimTec1_004653 Cc1cc(=O)[nH]c2nn(c(O)c12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D12 compound treatment 0.217 -0.0126 -1.74 0.224 -0.00131 -0.19 -1.3674 -0.7794 3085903 TimTec1_004654 CCOC(=O)C1=C(O)CN(C)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D13 compound treatment 0.234 0.00438 0.6 0.24 0.0147 2.12 1.9275 0.8738 3211410 TimTec1_004655 Cc1nn(C(=O)c2ccc(F)cc2)c(N)c1c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D14 compound treatment 0.221 -0.00862 -1.19 0.22 -0.00531 -0.77 -1.3852 -0.9773 3085905 TimTec1_004656 CCn1ncc(Cl)c(Cl)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D15 compound treatment 0.333 0.103 14.28 0.326 0.101 14.54 20.3825 1.0 3211411 TimTec1_004657 COc1cc(C)c(cc1C(C)C)S(=O)(=O)Nc2ccc3nc(C)sc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D16 compound treatment 0.234 0.00438 0.6 0.232 0.00669 0.97 1.1104 0.9745 1577125 TimTec1_004658 CCOC(=O)CCCN1C(CCc2ccccc12)C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D17 compound treatment 0.272 0.0424 5.85 0.283 0.0577 8.33 10.0316 0.9851 3211412 TimTec1_004659 C1CC1Nc2nc(nc(n2)n3ccnc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D18 compound treatment 0.226 -0.00362 -0.5 0.221 -0.00431 -0.62 -0.7946 -0.9941 1034819 TimTec1_004660 CC(O)(c1ccccc1)C(C)(O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D19 compound treatment 0.224 -0.00562 -0.78 0.219 -0.00631 -0.91 -1.1942 -0.9968 3211413 TimTec1_004661 O=S(=O)(Cc1ccccc1C#N)c2nc3cccnc3[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D20 compound treatment 0.226 -0.00362 -0.5 0.219 -0.00631 -0.91 -0.9989 -0.9602 3211414 TimTec1_004662 Oc1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D21 compound treatment 0.225 -0.00462 -0.64 0.222 -0.00331 -0.48 -0.7901 -0.9898 3085910 TimTec1_004663 CN(C(=O)CSc1nc(C)cc2COC(=O)c21)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D22 compound treatment 0.222 -0.00762 -1.05 0.218 -0.00731 -1.06 -1.4918 -1.0 3085911 TimTec1_004664 Cc1cc(=O)n(CNC(=O)c2ccco2)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D23 mock treatment 0.229 -6.25E-4 -0.09 0.229 0.00369 0.53 0.3156 0.5848 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 D24 positive control 0.233 0.00338 0.47 0.227 0.00169 0.24 0.5021 0.9542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E01 compound treatment 0.522 0.292 40.39 0.533 0.308 44.44 59.9881 0.9989 3211415 TimTec1_004665 O/N=C(/C#N)\c1nc2ccccc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E02 compound treatment 0.221 -0.00862 -1.19 0.215 -0.0103 -1.49 -1.8959 -0.9939 1640993 TimTec1_004666 CCOc1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccccc5C4=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E03 compound treatment 0.35 0.12 16.63 0.285 0.0597 8.62 17.8555 0.9532 1162299 TimTec1_004667 COc1ccc(cc1)c2nnc(NC(=O)CC(C)C)s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E04 compound treatment 0.222 -0.00762 -1.05 0.216 -0.00931 -1.35 -1.696 -0.9927 3085914 TimTec1_004668 Cc1nnc(SCC(=O)c2ccc(Cl)cc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E05 compound treatment 0.222 -0.00762 -1.05 0.216 -0.00931 -1.35 -1.696 -0.9927 3211416 TimTec1_004669 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccc(C)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E06 compound treatment 0.223 -0.00662 -0.92 0.221 -0.00431 -0.62 -1.0877 -0.9824 3211417 TimTec1_004670 OC(=O)CSc1nnc(c2ccccc2Br)n1C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E07 compound treatment 0.23 3.75E-4 0.05 0.222 -0.00331 -0.48 -0.3017 -0.6269 1165665 TimTec1_004671 CC(C)N1C(=O)CCNc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E08 compound treatment 0.351 0.121 16.77 0.338 0.113 16.28 23.3666 0.9999 3085950 TimTec1_004672 Clc1ccc(SCc2[nH]n(c3nc4ccccc4s3)c(=O)c2/C=N/Cc5ccco5)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E09 compound treatment 0.221 -0.00862 -1.19 0.218 -0.00731 -1.06 -1.5894 -0.9982 1675123 TimTec1_004673 COc1cc(CNC(=O)C2CCCC2)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E10 compound treatment 0.221 -0.00862 -1.19 0.216 -0.00931 -1.35 -1.7937 -0.9982 1569434 TimTec1_004674 CCn1c(=N)n(CC(=O)c2ccc(Br)cc2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E11 compound treatment 0.203 -0.0266 -3.68 0.217 -0.00831 -1.2 -3.45 -0.8916 3085953 TimTec1_004675 CC(C)(C)Nc1nc(=O)[nH]c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E12 compound treatment 0.212 -0.0176 -2.43 0.217 -0.00831 -1.2 -2.5708 -0.9469 3211418 TimTec1_004676 C[C@H]1C[C@H](C2C(=NNC2=O)C)N(N1c3ccccc3)C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E13 compound treatment 0.221 -0.00862 -1.19 0.229 0.00369 0.53 -0.4659 -0.357 1364377 TimTec1_004677 CN(Cc1ccccc1)Cc2c(O)ccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E14 compound treatment 0.214 -0.0156 -2.16 0.218 -0.00731 -1.06 -2.2733 -0.9459 3211419 TimTec1_004678 O=C(C1CCCCC1)n2cnc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E15 compound treatment 0.236 0.00637 0.88 0.228 0.00269 0.39 0.8973 0.9322 3085956 TimTec1_004679 Cn1c(=O)c(C#N)c(c2ccccc2)n3cnnc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E16 compound treatment 0.226 -0.00362 -0.5 0.222 -0.00331 -0.48 -0.6925 -0.9997 3085958 TimTec1_004680 C=CCNC(=O)C#Cc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E17 compound treatment 0.239 0.00937 1.3 0.24 0.0147 2.12 2.416 0.972 3211420 TimTec1_004681 CCOC(=O)n1ncc(C#N)c1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E18 compound treatment 0.226 -0.00362 -0.5 0.223 -0.00231 -0.33 -0.5903 -0.9806 1935336 TimTec1_004682 CC(=O)OC1CC(C)(C)N(O)C(C)(C)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E19 compound treatment 0.227 -0.00262 -0.36 0.224 -0.00131 -0.19 -0.3905 -0.9542 1210397 TimTec1_004683 CC1CN(OC(O1)c2cccc(O)c2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E20 compound treatment 0.25 0.0204 2.81 0.256 0.0307 4.43 5.1248 0.976 3085961 TimTec1_004684 CCN(N)c1nc(Cl)cc(C)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E21 compound treatment 0.221 -0.00862 -1.19 0.218 -0.00731 -1.06 -1.5894 -0.9982 1723779 TimTec1_004685 COC(C(=O)Nc1ccc(Cl)cn1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E22 compound treatment 0.218 -0.0116 -1.61 0.211 -0.0143 -2.07 -2.5975 -0.9922 1263589 TimTec1_004686 NCC1(CC2CC3C1)CC(CN)(C2)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E23 mock treatment 0.23 3.75E-4 0.05 0.224 -0.00131 -0.19 -0.0974 -0.4957 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 E24 positive control 0.235 0.00537 0.74 0.227 0.00169 0.24 0.6974 0.8924 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F01 compound treatment 0.223 -0.00662 -0.92 0.22 -0.00531 -0.77 -1.1898 -0.9962 1717073 TimTec1_004687 COc1ccc(CC2C(=O)NC(=O)N(C2=O)c3cccc(Cl)c3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F02 compound treatment 0.225 -0.00462 -0.64 0.225 -3.12E-4 -0.05 -0.4837 -0.7552 3085964 TimTec1_004688 S=C(NC(c1ccccc1)c2ccccc2)Nc3cccnc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F03 compound treatment 0.277 0.0474 6.54 0.274 0.0487 7.03 9.6008 0.9994 1738878 TimTec1_004689 CC(C)(C)c1nnc(Nc2ccc3OCOc3c2)n(N)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F04 compound treatment 0.219 -0.0106 -1.47 0.218 -0.00731 -1.06 -1.7848 -0.987 3085966 TimTec1_004690 OCc1ccccc1NC(=S)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F05 compound treatment 0.335 0.105 14.56 0.317 0.0917 13.24 19.6587 0.9989 3211421 TimTec1_004691 FC(F)(F)c1cccc(c1)N2C(Nc3ccccc3C2=O)c4ccc5cccnc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F06 compound treatment 0.221 -0.00862 -1.19 0.222 -0.00331 -0.48 -1.1809 -0.9197 1429088 TimTec1_004692 CC(C)CCOc1ccc(cc1)C2(C)NC(=O)N(CN3CCOCC3)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F07 compound treatment 0.232 0.00238 0.33 0.227 0.00169 0.24 0.4044 0.9893 3085968 TimTec1_004693 CCC(=O)Oc1ccc(cc1OC)C2CC(=O)c3c(N2)ccc4ccccc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F08 compound treatment 0.244 0.0144 1.99 0.237 0.0117 1.69 2.598 0.9967 3085970 TimTec1_004694 OC(=O)c1cc(on1)c2ccc(O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F09 compound treatment 0.288 0.0584 8.06 0.296 0.0707 10.21 12.9224 0.9932 3211422 TimTec1_004695 COc1ccc(cc1)C(=O)c2[nH]c(cc2c3ccccc3)c4ccc(OC)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F10 compound treatment 0.237 0.00737 1.02 0.234 0.00869 1.25 1.6078 0.9947 1353733 TimTec1_004696 CCOC(=O)C1=C(CN(C1)C(=O)c2ccccc2)NN(C)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F11 compound treatment 0.229 -6.25E-4 -0.09 0.233 0.00769 1.11 0.7241 0.6502 3085972 TimTec1_004697 Oc1[nH]nc2nc(cc(c12)C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F12 compound treatment 0.215 -0.0146 -2.02 0.221 -0.00431 -0.62 -1.8692 -0.8841 3211423 TimTec1_004698 CN(C1=C(C)CN(C2CCCCC2)C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F13 compound treatment 0.26 0.0304 4.2 0.256 0.0307 4.43 6.1016 0.9996 3211424 TimTec1_004699 Cc1nn(C(=O)COc2ccc(Cl)cc2Cl)c(N)c1c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F14 compound treatment 0.226 -0.00362 -0.5 0.238 0.0127 1.83 0.9418 0.4957 3086016 TimTec1_004700 COc1ccc(cc1)N(C(C)C2C(C)(C)C2(C)C)C(=O)Nc3ccccc3N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F15 compound treatment 0.213 -0.0166 -2.3 0.218 -0.00731 -1.06 -2.3709 -0.9379 3211510 TimTec1_004701 OC1(N(C2CC2)C(=O)c3ccccc31)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F16 compound treatment 0.225 -0.00462 -0.64 0.228 0.00269 0.39 -0.1773 -0.2372 1249129 TimTec1_004702 CCC1(COCc2ccccc2)CCC(O1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F17 compound treatment 0.262 0.0324 4.47 0.277 0.0517 7.47 8.4419 0.97 3211511 TimTec1_004703 CCN(Cc1ccccc1)C(=O)c2sc3nc(C)cc(C)c3c2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F18 compound treatment 0.238 0.00837 1.16 0.242 0.0167 2.41 2.5226 0.9435 3086019 TimTec1_004704 COc1ccc2/C(=N/N)/CCCc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F19 compound treatment 0.296 0.0664 9.17 0.298 0.0727 10.5 13.9082 0.9977 3211512 TimTec1_004705 Nc1nnc(s1)c2ccc(Cn3c(nc4ccccc34)c5cncs5)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F20 compound treatment 0.243 0.0134 1.85 0.242 0.0167 2.41 3.011 0.9914 3211513 TimTec1_004706 CS(=O)(=O)c1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F21 compound treatment 0.218 -0.0116 -1.61 0.216 -0.00931 -1.35 -2.0868 -0.9961 1223782 TimTec1_004707 OCC1CCCCN1C(=S)NCCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F22 compound treatment 0.276 0.0464 6.41 0.279 0.0537 7.75 10.0138 0.9955 3211514 TimTec1_004708 COc1ccc2C(=O)/C(=N\O)/CCCc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F23 mock treatment 0.23 3.75E-4 0.05 0.223 -0.00231 -0.33 -0.1996 -0.5904 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 F24 positive control 0.233 0.00338 0.47 0.227 0.00169 0.24 0.5021 0.9542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G01 compound treatment 0.276 0.0464 6.41 0.277 0.0517 7.47 9.8095 0.9971 1356880 TimTec1_004709 OC(=O)c1cc(nc2ccc(Br)cc12)c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G02 compound treatment 0.279 0.0494 6.82 0.279 0.0537 7.75 10.3069 0.998 3211515 TimTec1_004710 Brc1ccc(cc1)C2=CC(=O)OC(O2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G03 compound treatment 0.249 0.0194 2.68 0.254 0.0287 4.14 4.8228 0.9776 2106889 TimTec1_004711 Nc1nc(Cl)cc(Oc2ccc(Cl)cc2)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G04 compound treatment 0.213 -0.0166 -2.3 0.214 -0.0113 -1.63 -2.7795 -0.9861 1151915 TimTec1_004712 CN1C(=O)C(Cc2c(C)[nH]c3ccccc23)C(=O)N(C)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G05 compound treatment 0.221 -0.00862 -1.19 0.227 0.00169 0.24 -0.6702 -0.551 1509629 TimTec1_004713 Cn1c(SCC(=O)c2ccc3CCCCc3c2)nc4ccccc4c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G06 compound treatment 0.213 -0.0166 -2.3 0.222 -0.00331 -0.48 -1.9624 -0.8365 1368472 TimTec1_004714 Cc1nonc1NC(=O)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G07 compound treatment 0.26 0.0304 4.2 0.252 0.0267 3.85 5.6931 0.9991 1733999 TimTec1_004715 S=C1CCN(Cc2ccccc2)c3ccccc3N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G08 compound treatment 0.23 3.75E-4 0.05 0.222 -0.00331 -0.48 -0.3017 -0.6269 1463893 TimTec1_004716 CN1CCN(CC1)C(=O)c2c(C)oc3cc4c(C(=O)N5CCN(C)CC5)c(C)oc4cc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G09 compound treatment 0.229 -6.25E-4 -0.09 0.219 -0.00631 -0.91 -0.7058 -0.7706 3086027 TimTec1_004717 CCOc1ccc2nc(NC(NC(=O)CC)(C(F)(F)F)C(F)(F)F)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G10 compound treatment 0.233 0.00338 0.47 0.237 0.0117 1.69 1.5234 0.8698 3211516 TimTec1_004718 Fc1ccc(cc1)c2n[nH]cc2C=C3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G11 compound treatment 0.219 -0.0106 -1.47 0.216 -0.00931 -1.35 -1.9891 -0.999 1735827 TimTec1_004719 CCN(CC)C(=S)Nc1ccc2oc(nc2c1)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G12 compound treatment 0.22 -0.00962 -1.33 0.221 -0.00431 -0.62 -1.3807 -0.9403 3211517 TimTec1_004720 CC1(NN(C(=S)N1)c2ccccc2)C3(C)COCOC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G13 compound treatment 0.22 -0.00962 -1.33 0.224 -0.00131 -0.19 -1.0743 -0.7998 3086031 TimTec1_004721 CCOc1ccccc1C(=O)n2cc(Cl)cn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G14 compound treatment 0.207 -0.0226 -3.13 0.225 -3.12E-4 -0.05 -2.2421 -0.7172 1425223 TimTec1_004722 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cc(C)on4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G15 compound treatment 0.347 0.117 16.22 0.384 0.159 22.92 27.6742 0.9856 1383059 TimTec1_004723 CC1CCN(CC1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G16 compound treatment 0.244 0.0144 1.99 0.26 0.0347 5.01 4.9472 0.9179 1606397 TimTec1_004724 O=S(=O)(NCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G17 compound treatment 0.287 0.0574 7.93 0.289 0.0637 9.2 12.1098 0.9972 3211518 TimTec1_004725 COc1ccc(CCN2C(CC(=O)N)C(=O)N(C2=S)c3cccc(c3)C(F)(F)F)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G18 compound treatment 0.223 -0.00662 -0.92 0.225 -3.12E-4 -0.05 -0.6791 -0.7411 3086077 TimTec1_004726 Clc1cccc(c1)C2CC(=O)C(=CNC3CCCC3)C(=O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G19 compound treatment 0.254 0.0244 3.37 0.261 0.0357 5.15 6.0262 0.9787 1327319 TimTec1_004727 COc1ccc(cc1OC)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G20 compound treatment 0.227 -0.00262 -0.36 0.231 0.00569 0.82 0.3245 0.3613 1653659 TimTec1_004728 Clc1ccc(cc1)c2csc3c4ncnc4ncn23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G21 compound treatment 0.329 0.0994 13.73 0.33 0.105 15.12 20.4003 0.9988 3211519 TimTec1_004729 Cn1c(/C=C/C(=O)O)nc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G22 compound treatment 0.225 -0.00462 -0.64 0.222 -0.00331 -0.48 -0.7901 -0.9898 3211520 TimTec1_004730 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G23 mock treatment 0.23 3.75E-4 0.05 0.227 0.00169 0.24 0.209 0.8387 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 G24 positive control 0.232 0.00238 0.33 0.225 -3.12E-4 -0.05 0.2001 0.6041 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H01 compound treatment 0.244 0.0144 1.99 0.24 0.0147 2.12 2.9044 0.9995 1710338 TimTec1_004731 Cn1c(CS(=O)(=O)c2ccccc2)c(C#N)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H02 compound treatment 0.221 -0.00862 -1.19 0.221 -0.00431 -0.62 -1.283 -0.9542 3211521 TimTec1_004732 Clc1ccc(CS(=O)(=O)c2nc3cccnc3[nH]2)c(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H03 compound treatment 0.238 0.00837 1.16 0.235 0.00969 1.4 1.8076 0.9955 3086082 TimTec1_004733 Cc1[nH]c2ccccc2c1CCN3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H04 compound treatment 0.21 -0.0196 -2.71 0.217 -0.00831 -1.2 -2.7661 -0.9329 3211522 TimTec1_004734 O=C(NC(=O)c1cccs1)OC[C@@H]2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H05 compound treatment 0.215 -0.0146 -2.02 0.221 -0.00431 -0.62 -1.8692 -0.8841 3086084 TimTec1_004735 OC(=O)CCc1ccc(c2ccccc2)n1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H06 compound treatment 0.222 -0.00762 -1.05 0.227 0.00169 0.24 -0.5725 -0.5295 3211523 TimTec1_004736 OC1(CC(=NN1C(=O)c2cccnc2)C(F)(F)F)c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H07 compound treatment 0.28 0.0504 6.96 0.298 0.0727 10.5 12.3452 0.9801 3211524 TimTec1_004737 Fc1cccc(c1)C(=O)NC(=O)Nc2nc(cc(n2)C(F)(F)F)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H08 compound treatment 0.244 0.0144 1.99 0.232 0.00669 0.97 2.0873 0.9452 3086087 TimTec1_004738 Fc1ccccc1CCNc2c3CCCCc3nc4ncnn24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H09 compound treatment 0.224 -0.00562 -0.78 0.219 -0.00631 -0.91 -1.1942 -0.9968 3086089 TimTec1_004739 Cc1ccoc1C(=O)NCCN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H10 compound treatment 0.297 0.0674 9.31 0.298 0.0727 10.5 14.0059 0.9982 1653767 TimTec1_004740 CCOC(=O)C1=C(NC(C)C)C(=O)N(C1)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H11 compound treatment 0.222 -0.00762 -1.05 0.216 -0.00931 -1.35 -1.696 -0.9927 3211525 TimTec1_004741 CC1Cc2nn(c(c2C(=O)C1C)c3cccnc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H12 compound treatment 0.229 -6.25E-4 -0.09 0.224 -0.00131 -0.19 -0.1951 -0.9366 1563400 TimTec1_004742 CN1CC(=C(NC2CCCCC2)C1=O)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H13 compound treatment 0.224 -0.00562 -0.78 0.219 -0.00631 -0.91 -1.1942 -0.9968 3211526 TimTec1_004743 O=C1N(Cc2cccnc2)C(NCc3cccnc3)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H14 compound treatment 0.22 -0.00962 -1.33 0.224 -0.00131 -0.19 -1.0743 -0.7998 3086093 TimTec1_004744 Cc1cc(C)[n+]2c(csc2n1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H15 compound treatment 0.507 0.277 38.32 0.518 0.293 42.28 56.9907 0.9988 1868951 TimTec1_004745 CCOC(=O)c1c(C)cc(C)[nH]c1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H16 compound treatment 0.23 3.75E-4 0.05 0.238 0.0127 1.83 1.3325 0.7268 1285461 TimTec1_004746 COc1cc(C(=O)CN2C(=O)c3ccccc3C2=O)c(OC)cc1Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H17 compound treatment 0.222 -0.00762 -1.05 0.222 -0.00331 -0.48 -1.0832 -0.9362 3086156 TimTec1_004747 CCOc1ccc(CCNC(=O)Cc2nnc[nH]2)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H18 compound treatment 0.221 -0.00862 -1.19 0.221 -0.00431 -0.62 -1.283 -0.9542 1091806 TimTec1_004748 CCC1C[N+]2(C)CCc3cc(OC)c(OC)cc3C2CC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H19 compound treatment 0.225 -0.00462 -0.64 0.225 -3.12E-4 -0.05 -0.4837 -0.7552 3086159 TimTec1_004749 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H20 compound treatment 0.234 0.00438 0.6 0.23 0.00469 0.68 0.9062 0.9984 3211527 TimTec1_004750 CS(=O)(=O)c1ccc(C(=O)O)c(O)c1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H21 compound treatment 0.231 0.00138 0.19 0.231 0.00569 0.82 0.7152 0.8482 3211528 TimTec1_004751 CC(C)(C)NC(=O)Cn1nnc(n1)c2ccc(cc2)S(=O)(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H22 compound treatment 0.219 -0.0106 -1.47 0.217 -0.00831 -1.2 -1.887 -0.995 1019007 TimTec1_004752 COc1ncnc2[nH]cnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H23 mock treatment 0.228 -0.00162 -0.22 0.228 0.00269 0.39 0.1158 0.2581 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 H24 positive control 0.233 0.00338 0.47 0.224 -0.00131 -0.19 0.1956 0.3887 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I01 compound treatment 0.223 -0.00662 -0.92 0.222 -0.00331 -0.48 -0.9855 -0.9542 1573225 TimTec1_004753 O=C(N1CCOCC1)c2ccccc2C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I02 compound treatment 0.252 0.0224 3.09 0.249 0.0237 3.42 4.6052 0.9987 1382795 TimTec1_004754 O=C(CSc1ccccn1)c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I03 compound treatment 0.225 -0.00462 -0.64 0.217 -0.00831 -1.2 -1.3008 -0.9564 1128047 TimTec1_004755 O=C(Oc1cccc2cccnc12)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I04 compound treatment 0.218 -0.0116 -1.61 0.218 -0.00731 -1.06 -1.8825 -0.9793 1498538 TimTec1_004756 CC(NC(=O)c1nc[nH]n1)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I05 compound treatment 0.213 -0.0166 -2.3 0.22 -0.00531 -0.77 -2.1667 -0.8947 1694793 TimTec1_004757 NC(=O)N1CCC(=O)Nc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I06 compound treatment 0.212 -0.0176 -2.43 0.222 -0.00331 -0.48 -2.0601 -0.8302 1660022 TimTec1_004758 CC12CCCCC2N(CC(=O)N)c3ccccc31 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I07 compound treatment 0.35 0.12 16.63 0.335 0.11 15.84 22.9625 0.9997 1335680 TimTec1_004759 Cc1nc2ccccn2c1c3csc(Nc4ccc(C)cc4C)n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I08 compound treatment 0.221 -0.00862 -1.19 0.22 -0.00531 -0.77 -1.3852 -0.9773 1266099 TimTec1_004760 Clc1ccc2oc(=O)n(C(=O)Oc3ccccc3)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I09 compound treatment 0.221 -0.00862 -1.19 0.217 -0.00831 -1.2 -1.6916 -1.0 3211606 TimTec1_004761 OC(=O)C(Cc1ccccc1)P(=O)(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I10 compound treatment 0.226 -0.00362 -0.5 0.229 0.00369 0.53 0.0225 0.0308 3086166 TimTec1_004762 COc1ccc(c2nnc3ccc(Cl)nn23)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I11 compound treatment 0.297 0.0674 9.31 0.313 0.0877 12.67 15.538 0.9885 1268857 TimTec1_004763 COc1ccc(c2csc(n2)C3COc4ccccc4O3)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I12 compound treatment 0.223 -0.00662 -0.92 0.222 -0.00331 -0.48 -0.9855 -0.9542 1370075 TimTec1_004764 CN(C(=O)Cn1nnnc1N)C2(CCCCC2)C(=O)Nc3ccccc3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I13 compound treatment 0.224 -0.00562 -0.78 0.223 -0.00231 -0.33 -0.7857 -0.9289 1698831 TimTec1_004765 O=c1nc(Nc2ccccc2)[nH]c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I14 compound treatment 0.347 0.117 16.22 0.339 0.114 16.42 23.0779 1.0 3211607 TimTec1_004766 Cc1ccc(/C(=C/C2=NCCNC(C2)c3ccccc3)/O)c(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I15 compound treatment 0.208 -0.0216 -2.99 0.216 -0.00931 -1.35 -3.0637 -0.9351 1314790 TimTec1_004767 COC(C(=O)NCc1cccnc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I16 compound treatment 0.257 0.0274 3.78 0.267 0.0417 6.02 6.9321 0.9749 3211608 TimTec1_004768 CCCC/1=NN(C(=O)\C1=C/N)c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I17 compound treatment 0.227 -0.00262 -0.36 0.226 6.88E-4 0.1 -0.1862 -0.4952 1621835 TimTec1_004769 CCN(CC)c1ccc2c(=O)[nH][nH]c(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I18 compound treatment 0.258 0.0284 3.92 0.253 0.0277 4.0 5.5998 0.9999 1274514 TimTec1_004770 Fc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I19 compound treatment 0.233 0.00338 0.47 0.236 0.0107 1.54 1.4213 0.8814 1017274 TimTec1_004771 CCOC(=O)c1cnc2ccc(OC)cc2c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I20 compound treatment 0.226 -0.00362 -0.5 0.218 -0.00731 -1.06 -1.101 -0.9419 1179846 TimTec1_004772 O=C(c1ccccc1)c2ccc(cc2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I21 compound treatment 0.218 -0.0116 -1.61 0.214 -0.0113 -1.63 -2.2911 -1.0 1674029 TimTec1_004773 CCCCC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I22 compound treatment 0.277 0.0474 6.54 0.278 0.0527 7.61 10.0094 0.9972 1703643 TimTec1_004774 COCc1cc(C)nc2sc3C(=O)NC(Nc3c12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I23 mock treatment 0.232 0.00238 0.33 0.226 6.88E-4 0.1 0.3022 0.8816 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 I24 positive control 0.237 0.00737 1.02 0.222 -0.00331 -0.48 0.3821 0.3395 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J01 compound treatment 0.28 0.0504 6.96 0.278 0.0527 7.61 10.3024 0.999 1596975 TimTec1_004775 COc1ccc(cc1)C(=O)n2c(=S)nc3cc(C)ccn23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J02 compound treatment 0.296 0.0664 9.17 0.285 0.0597 8.62 12.5804 0.9995 3211609 TimTec1_004776 Cc1ccc(cc1)C(=O)OC2CC(OC2CO)n3ccc(NC(=O)c4ccccc4)nc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J03 compound treatment 0.299 0.0694 9.58 0.282 0.0567 8.19 12.5671 0.9969 1526337 TimTec1_004777 COc1ccc(cc1)C2=C(CC(=O)O)C(=O)CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J04 compound treatment 0.221 -0.00862 -1.19 0.22 -0.00531 -0.77 -1.3852 -0.9773 3211610 TimTec1_004778 Cc1ccc(cc1)C(=O)NC(=O)OC[C@@H]2CCCN3CCCCC23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J05 compound treatment 0.239 0.00937 1.3 0.237 0.0117 1.69 2.1096 0.9914 1520302 TimTec1_004779 C(Cn1c(COc2ccccc2)nc3ccccc13)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J06 compound treatment 0.222 -0.00762 -1.05 0.225 -3.12E-4 -0.05 -0.7768 -0.7367 1554201 TimTec1_004780 Cc1ccc(cc1)N(C(=O)c2ccccn2)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J07 compound treatment 0.31 0.0804 11.1 0.332 0.107 15.41 18.7485 0.9871 3211611 TimTec1_004781 Cc1ccc(cc1C)n2nc(C(=O)O)c(/C=C/c3ccc(Cl)cc3Cl)c(C#N)c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J08 compound treatment 0.234 0.00438 0.6 0.239 0.0137 1.98 1.8254 0.8829 3086243 TimTec1_004782 Clc1ccc(NCc2ccccc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J09 compound treatment 0.264 0.0344 4.75 0.263 0.0377 5.44 7.2074 0.9977 3211612 TimTec1_004783 C(c1cn(Cc2ccccc2)nn1)n3nnc(n3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J10 compound treatment 0.219 -0.0106 -1.47 0.221 -0.00431 -0.62 -1.4784 -0.9272 1008095 TimTec1_004784 NC(=S)Nc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J11 compound treatment 0.221 -0.00862 -1.19 0.221 -0.00431 -0.62 -1.283 -0.9542 3211613 TimTec1_004785 OC(=O)CCN1CCn2c1nc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J12 compound treatment 0.302 0.0724 10.0 0.305 0.0797 11.51 15.2093 0.9975 1404920 TimTec1_004786 CCOC(=O)C1=C(NC2CCCCC2)C(=O)N(C1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J13 compound treatment 0.226 -0.00362 -0.5 0.23 0.00469 0.68 0.1247 0.148 3211614 TimTec1_004787 CCOc1ccc(CC(=O)C2C(=O)CC(C)(C)CC2=O)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J14 compound treatment 0.214 -0.0156 -2.16 0.224 -0.00131 -0.19 -1.6604 -0.7663 1418487 TimTec1_004788 CCOC(=O)c1nccnc1N(C(=O)c2ccc(C)cc2)C(=O)c3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J15 compound treatment 0.293 0.0634 8.76 0.29 0.0647 9.34 12.798 0.9995 3086247 TimTec1_004789 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC4CCCC4)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J16 compound treatment 0.214 -0.0156 -2.16 0.222 -0.00331 -0.48 -1.8647 -0.8434 3211615 TimTec1_004790 CSC(=S)NCc1cccs1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J17 compound treatment 0.317 0.0874 12.07 0.326 0.101 14.54 18.8195 0.9957 3211616 TimTec1_004791 CCC1(CN2CC3(CC)CN(C1)C2c4c(C)[nH]c5ccccc45)C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J18 compound treatment 0.217 -0.0126 -1.74 0.218 -0.00731 -1.06 -1.9802 -0.9711 1118951 TimTec1_004792 CC1=CC(=O)CN(C1)S(=O)(=O)c2ccc(C)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J19 compound treatment 0.227 -0.00262 -0.36 0.226 6.88E-4 0.1 -0.1862 -0.4952 3086250 TimTec1_004793 CS(=O)(=O)NCc1ccc(cc1)C(=O)NCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J20 compound treatment 0.227 -0.00262 -0.36 0.222 -0.00331 -0.48 -0.5948 -0.9907 3211617 TimTec1_004794 Fc1cccc2ncnc(OCc3ccccc3)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J21 compound treatment 0.239 0.00937 1.3 0.241 0.0157 2.27 2.5181 0.9648 3211618 TimTec1_004795 COc1ccccc1NC(=O)C(F)(F)C(=O)Nc2ccccc2OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J22 compound treatment 0.22 -0.00962 -1.33 0.216 -0.00931 -1.35 -1.8914 -1.0 1295066 TimTec1_004796 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)CCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J23 mock treatment 0.231 0.00138 0.19 0.229 0.00369 0.53 0.511 0.9035 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 J24 positive control 0.235 0.00537 0.74 0.228 0.00269 0.39 0.7996 0.9542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K01 compound treatment 0.294 0.0644 8.89 0.291 0.0657 9.49 12.9979 0.9995 3211619 TimTec1_004797 Cc1ccc(NC(=O)c2ccccc2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K02 compound treatment 0.268 0.0384 5.3 0.239 0.0137 1.98 5.1468 0.9096 1736764 TimTec1_004798 CC(C)Cc1nc(C#N)c(N)c(c1C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K03 compound treatment 0.388 0.158 21.88 0.376 0.151 21.77 30.8623 1.0 1338385 TimTec1_004799 CN(C)N=Nc1ccc(cc1)S(=O)(=O)N(C(=O)C)C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K04 compound treatment 0.338 0.108 14.97 0.331 0.106 15.27 21.3817 1.0 1523329 TimTec1_004800 COc1cc(ccc1O)C2N(Cc3ccccc3)CCCN2Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K05 compound treatment 0.223 -0.00662 -0.92 0.221 -0.00431 -0.62 -1.0877 -0.9824 1577188 TimTec1_004801 CC1CC(=O)Nc2ccccc2N1C=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K06 compound treatment 0.27 0.0404 5.58 0.263 0.0377 5.44 7.7935 0.9999 1555913 TimTec1_004802 Cc1ccc(NC(=O)C2(CCCCC2)NC(=O)c3ccc(cc3)n4cnnn4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K07 compound treatment 0.227 -0.00262 -0.36 0.234 0.00869 1.25 0.6309 0.483 3211620 TimTec1_004803 Cc1nc2ccccn2c1c3csc(Nc4ccc(Br)cc4Br)n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K08 compound treatment 0.226 -0.00362 -0.5 0.226 6.88E-4 0.1 -0.2839 -0.5561 3086325 TimTec1_004804 OCC1(CCCCC1)C2=NOC(O)(C2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K09 compound treatment 0.215 -0.0146 -2.02 0.217 -0.00831 -1.2 -2.2777 -0.9691 1021311 TimTec1_004805 C[N+]1(CC[N+]2(C)CCCCC2)CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K10 compound treatment 0.219 -0.0106 -1.47 0.221 -0.00431 -0.62 -1.4784 -0.9272 1399338 TimTec1_004806 OC(C1CN2CCC1CC2)(c3cccc(Cl)c3)c4cccc(Cl)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K11 compound treatment 0.232 0.00238 0.33 0.234 0.00869 1.25 1.1193 0.863 3086328 TimTec1_004807 Cc1ccc(CC2SC(=NC2=O)N3CCN(CC3)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K12 compound treatment 0.331 0.101 14.01 0.307 0.0817 11.8 18.2465 0.9964 1611430 TimTec1_004808 CC1CCc2nc3ccc4ccccc4c3c(c5ccc(O)c(O)c5)c2C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K13 compound treatment 0.222 -0.00762 -1.05 0.225 -3.12E-4 -0.05 -0.7768 -0.7367 1442519 TimTec1_004809 CC(=O)OC1CCC(C(OC(=O)C)C1[N+](C)(C)C)[N+](C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K14 compound treatment 0.218 -0.0116 -1.61 0.222 -0.00331 -0.48 -1.474 -0.8796 1912712 TimTec1_004810 CC1=CC(C)(C)C(C(C1)C(=O)O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K15 compound treatment 0.217 -0.0126 -1.74 0.218 -0.00731 -1.06 -1.9802 -0.9711 1608847 TimTec1_004811 Cc1ccc(cc1)S(=O)(=O)N2N=NC3C4CC(C5CC=CC54)C32 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K16 compound treatment 0.266 0.0364 5.03 0.275 0.0497 7.18 8.6284 0.9848 3211621 TimTec1_004812 FC(F)(F)c1cccc(NC(=O)NC2(CC2)c3ccccc3)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K17 compound treatment 0.222 -0.00762 -1.05 0.224 -0.00131 -0.19 -0.8789 -0.8212 3086332 TimTec1_004813 COc1nsc(Br)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K18 compound treatment 0.235 0.00537 0.74 0.239 0.0137 1.98 1.9231 0.9106 1299455 TimTec1_004814 CC1Nc2ccccc2C(=O)N1NC(=O)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K19 compound treatment 0.225 -0.00462 -0.64 0.222 -0.00331 -0.48 -0.7901 -0.9898 1278796 TimTec1_004815 O=C(Cc1ccccc1)N2CCC(=N2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K20 compound treatment 0.219 -0.0106 -1.47 0.22 -0.00531 -0.77 -1.5805 -0.9542 1293299 TimTec1_004816 COc1ccc(CCn2c(N)cc(=O)[nH]c2=O)cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K21 compound treatment 0.238 0.00837 1.16 0.235 0.00969 1.4 1.8076 0.9955 1371336 TimTec1_004817 CCCCC(=O)Nc1c(nc2ccccn12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K22 compound treatment 0.235 0.00537 0.74 0.232 0.00669 0.97 1.2081 0.9916 3211728 TimTec1_004818 Brc1cnn(c2ccccc2)c(=O)c1NCCCN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K23 mock treatment 0.23 3.75E-4 0.05 0.227 0.00169 0.24 0.209 0.8387 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 K24 positive control 0.233 0.00338 0.47 0.229 0.00369 0.53 0.7063 0.9978 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L01 compound treatment 0.273 0.0434 5.99 0.293 0.0677 9.78 11.1507 0.9724 1208379 TimTec1_004819 O=C(c1ccco1)n2c(=S)nc3ccccn23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L02 compound treatment 0.244 0.0144 1.99 0.219 -0.00631 -0.91 0.7595 0.3476 3211729 TimTec1_004820 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NCc3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L03 compound treatment 0.267 0.0374 5.16 0.226 6.88E-4 0.1 3.7213 0.7206 3211730 TimTec1_004821 CCOC(=O)c1nc(N)c(=O)n(n1)c2ccc(cc2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L04 compound treatment 0.229 -6.25E-4 -0.09 0.221 -0.00431 -0.62 -0.5015 -0.7975 3086338 TimTec1_004822 CN1C2=C(C(NC1=O)c3ccc(O)cc3)C(=O)N(CCO)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L05 compound treatment 0.229 -6.25E-4 -0.09 0.235 0.00969 1.4 0.9284 0.6622 3211731 TimTec1_004823 CC1(C)Cc2ccccc2C(=N1)c3sc4nc5CCCCCc5cc4c3N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L06 compound treatment 0.273 0.0434 5.99 0.293 0.0677 9.78 11.1507 0.9724 1225977 TimTec1_004824 Cc1cc(NC(=O)Cc2ccccc2)ccc1c3cc4ccccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L07 compound treatment 0.243 0.0134 1.85 0.23 0.00469 0.68 1.7853 0.9072 3086341 TimTec1_004825 CC(C)n1c(COc2ccc(Cl)cc2)nc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L08 compound treatment 0.297 0.0674 9.31 0.295 0.0697 10.07 13.6995 0.9992 1395920 TimTec1_004826 COC(=O)C1=C(CN(C1)c2ccccc2)NN(C)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L09 compound treatment 0.238 0.00837 1.16 0.229 0.00369 0.53 1.1948 0.938 3086343 TimTec1_004827 Cc1ccsc1CNn2cnnc2SCc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L10 compound treatment 0.254 0.0244 3.37 0.259 0.0337 4.87 5.8219 0.9838 3086416 TimTec1_004828 CN(NC(=S)Nc1ccccc1)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L11 compound treatment 0.289 0.0594 8.2 0.278 0.0527 7.61 11.1816 0.9993 3211732 TimTec1_004829 Cc1nn(C(=O)c2c[nH]c3ccccc23)c(N)c1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L12 compound treatment 0.233 0.00338 0.47 0.232 0.00669 0.97 1.0127 0.9442 3086420 TimTec1_004830 O/N=C/c1nc2ccccc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L13 compound treatment 0.226 -0.00362 -0.5 0.222 -0.00331 -0.48 -0.6925 -0.9997 3211733 TimTec1_004831 Nn1c(S)nnc1Cc2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L14 compound treatment 0.212 -0.0176 -2.43 0.211 -0.0143 -2.07 -3.1836 -0.9967 3086422 TimTec1_004832 OC/C=C/c1ccc(O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L15 compound treatment 0.25 0.0204 2.81 0.254 0.0287 4.14 4.9205 0.9822 3211734 TimTec1_004833 COc1ccc(c2cc(n[nH]2)C(=O)N)c(F)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L16 compound treatment 0.218 -0.0116 -1.61 0.22 -0.00531 -0.77 -1.6782 -0.9429 3086423 TimTec1_004834 CC(C)(C)c1ccc(cc1)S(=O)(=O)NC(=O)c2cccc(Oc3cccc(c3)C(F)(F)F)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L17 compound treatment 0.222 -0.00762 -1.05 0.223 -0.00231 -0.33 -0.9811 -0.8878 3211735 TimTec1_004835 OCC1OC(Nc2ccccn2)C(O)C(O)C1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L18 compound treatment 0.318 0.0884 12.21 0.344 0.119 17.14 20.7557 0.9862 1186126 TimTec1_004836 COc1ccc2c3CCc4c([nH]c5ccccc45)-c3ccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L19 compound treatment 0.245 0.0154 2.12 0.252 0.0267 3.85 4.2278 0.9606 3086426 TimTec1_004837 Cc1cccc(C)c1OCCN2C(=O)c3ccccc3C2(O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L20 compound treatment 0.252 0.0224 3.09 0.253 0.0277 4.0 5.0137 0.9919 1122321 TimTec1_004838 CCC1Nc2ccccc2NC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L21 compound treatment 0.221 -0.00862 -1.19 0.218 -0.00731 -1.06 -1.5894 -0.9982 1235395 TimTec1_004839 S=C(Nc1cccnc1)N(CCc2ccccc2)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L22 compound treatment 0.221 -0.00862 -1.19 0.219 -0.00631 -0.91 -1.4873 -0.9913 3086429 TimTec1_004840 O/N=C/C(=O)Nc1ccccc1I 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L23 mock treatment 0.228 -0.00162 -0.22 0.227 0.00169 0.24 0.0136 0.0411 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 L24 positive control 0.231 0.00138 0.19 0.225 -3.12E-4 -0.05 0.1024 0.5245 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M01 compound treatment 0.224 -0.00562 -0.78 0.224 -0.00131 -0.19 -0.6835 -0.8546 1539018 TimTec1_004841 CC(C)(C)NCC(O)COc1c(Br)ccc2c1sc3nc4CCCCCn4c(=O)c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M02 compound treatment 0.282 0.0524 7.24 0.247 0.0217 3.13 7.3315 0.9298 1251587 TimTec1_004842 CCCc1nc2c(sc3nc(COC)cc(C)c32)c4nc5ccccc5n14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M03 compound treatment 0.227 -0.00262 -0.36 0.224 -0.00131 -0.19 -0.3905 -0.9542 1774729 TimTec1_004843 O=C(OC1CS(=O)(=O)CC1OC(=O)c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M04 compound treatment 0.219 -0.0106 -1.47 0.221 -0.00431 -0.62 -1.4784 -0.9272 3086431 TimTec1_004844 CCC(=O)Nc1nc2nc(COC)cc(O)n2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M05 compound treatment 0.23 3.75E-4 0.05 0.221 -0.00431 -0.62 -0.4038 -0.6461 3211736 TimTec1_004845 CC1CC(=O)N(C(=O)C)c2ccccc2N1C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M06 compound treatment 0.24 0.0104 1.43 0.233 0.00769 1.11 1.7987 0.992 1645856 TimTec1_004846 CCOC(=O)CNc1nc(Cl)nc(NCC=C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M07 compound treatment 0.239 0.00937 1.3 0.224 -0.00131 -0.19 0.7818 0.5972 1505508 TimTec1_004847 OC(=O)CCNS(=O)(=O)c1ccc2ccccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M08 compound treatment 0.308 0.0784 10.83 0.31 0.0847 12.23 16.3061 0.9981 3211737 TimTec1_004848 OC(=O)Cn1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M09 compound treatment 0.223 -0.00662 -0.92 0.222 -0.00331 -0.48 -0.9855 -0.9542 3211738 TimTec1_004849 OC(C(O)c1nnc(S)n1c2ccccc2)c3nnc(S)n3c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M10 compound treatment 0.221 -0.00862 -1.19 0.22 -0.00531 -0.77 -1.3852 -0.9773 3086435 TimTec1_004850 OC(=O)c1ccc(CSc2nnc(Cc3ccccc3)n2c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M11 compound treatment 0.221 -0.00862 -1.19 0.221 -0.00431 -0.62 -1.283 -0.9542 3211739 TimTec1_004851 CCOC(=O)CN1NC(CC)(NC1=S)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M12 compound treatment 0.237 0.00737 1.02 0.23 0.00469 0.68 1.1992 0.9803 3211740 TimTec1_004852 Cc1onc(c1C(=O)NCCOC2(CC3CC4CC(C3)C2)C4)c5ccccc5Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M13 compound treatment 0.246 0.0164 2.26 0.248 0.0227 3.28 3.9169 0.9836 1320456 TimTec1_004853 Oc1ncnc2nn(nc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M14 compound treatment 0.22 -0.00962 -1.33 0.223 -0.00231 -0.33 -1.1764 -0.8581 1262859 TimTec1_004854 C=CCN1C(=O)C(Cc2c[nH]c3ccccc23)NC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M15 compound treatment 0.213 -0.0166 -2.3 0.208 -0.0173 -2.5 -3.3923 -0.9991 1260852 TimTec1_004855 COc1ccccc1N2CCSC2C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M16 compound treatment 0.251 0.0214 2.95 0.238 0.0127 1.83 3.384 0.9737 1602518 TimTec1_004856 COC(=O)c1cc(=O)c2c(SC)nc(nc2[nH]1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M17 compound treatment 0.239 0.00937 1.3 0.241 0.0157 2.27 2.5181 0.9648 1218046 TimTec1_004857 CC(C)(O)C#Cc1ccc(o1)C(=O)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M18 compound treatment 0.223 -0.00662 -0.92 0.224 -0.00131 -0.19 -0.7812 -0.8358 1375886 TimTec1_004858 CC(C)c1ccc(cc1)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M19 compound treatment 0.224 -0.00562 -0.78 0.224 -0.00131 -0.19 -0.6835 -0.8546 1685209 TimTec1_004859 O=C1NC(=O)C(CCc2ccccn2)(CCc3ccccn3)C(=O)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M20 compound treatment 0.457 0.227 31.41 0.487 0.262 37.8 48.9401 0.9958 3211741 TimTec1_004860 Cc1nnc(c2ccccc2)c(=O)n1/N=C/c3ccc(O)c(O)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M21 compound treatment 0.224 -0.00562 -0.78 0.223 -0.00231 -0.33 -0.7857 -0.9289 1591983 TimTec1_004861 O=C(NC1CCCCC1)n2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M22 compound treatment 0.222 -0.00762 -1.05 0.22 -0.00531 -0.77 -1.2875 -0.9879 3086509 TimTec1_004862 Cc1cc(C)n(n1)c2n[nH]c(=S)n2N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M23 mock treatment 0.231 0.00138 0.19 0.226 6.88E-4 0.1 0.2045 0.9542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 M24 positive control 0.226 -0.00362 -0.5 0.224 -0.00131 -0.19 -0.4882 -0.9117 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N01 compound treatment 0.235 0.00537 0.74 0.242 0.0167 2.41 2.2295 0.8839 1431780 TimTec1_004863 Oc1nnc(c2ncc[nH]2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N02 compound treatment 0.215 -0.0146 -2.02 0.217 -0.00831 -1.2 -2.2777 -0.9691 3211742 TimTec1_004864 CCOc1ccc(cc1S(=O)(=O)NC2CC2)n3cnnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N03 compound treatment 0.219 -0.0106 -1.47 0.218 -0.00731 -1.06 -1.7848 -0.987 3086512 TimTec1_004865 CCN1CN(Cc2ccccc2)CNC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N04 compound treatment 0.219 -0.0106 -1.47 0.216 -0.00931 -1.35 -1.9891 -0.999 3211743 TimTec1_004866 CC1(C2c3ccccc3OC(=O)C21C(=O)N4CCOCC4)C(=O)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N05 compound treatment 0.286 0.0564 7.79 0.286 0.0607 8.77 11.7057 0.9983 3211744 TimTec1_004867 CCCCn1c(cc(=O)c2c(C)n(c3ccccc3)c(=S)nc12)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N06 compound treatment 0.245 0.0154 2.12 0.25 0.0247 3.57 4.0235 0.9694 3086514 TimTec1_004868 Cc1cccc(NCc2c(C#N)c3ccccc3n2C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N07 compound treatment 0.23 3.75E-4 0.05 0.229 0.00369 0.53 0.4133 0.7722 3211745 TimTec1_004869 CCOc1nc(OCC)nc(n1)n2cc(nn2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N08 compound treatment 0.279 0.0494 6.82 0.294 0.0687 9.92 11.839 0.9833 1416515 TimTec1_004870 CCOC(=O)C1=C(NN(C)c2ccccc2)C(=O)N(C)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N09 compound treatment 0.156 -0.0736 -10.17 0.158 -0.0673 -9.72 -14.0674 -0.9997 3211746 TimTec1_004871 Nc1nc-2c(CCc3c2cnn3c4ccccc4)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N10 compound treatment 0.222 -0.00762 -1.05 0.223 -0.00231 -0.33 -0.9811 -0.8878 1675882 TimTec1_004872 CCOC(=O)C1=C(N)C(=O)N(CCCN2CCOCC2)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N11 compound treatment 0.277 0.0474 6.54 0.258 0.0327 4.72 7.9666 0.9872 3211837 TimTec1_004873 CCOc1nc(NC(=O)NC(=O)c2c(F)cccc2F)nc(n1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N12 compound treatment 0.23 3.75E-4 0.05 0.228 0.00269 0.39 0.3111 0.7944 3086517 TimTec1_004874 Cn1c(/C=N/O)nc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N13 compound treatment 0.229 -6.25E-4 -0.09 0.235 0.00969 1.4 0.9284 0.6622 3211838 TimTec1_004875 COC(=O)Nc1ccc2n(cnc2c1)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N14 compound treatment 0.269 0.0394 5.44 0.254 0.0287 4.14 6.7765 0.991 1164968 TimTec1_004876 O=C(NCCc1ccccc1)C2c3ccccc3-c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N15 compound treatment 0.221 -0.00862 -1.19 0.223 -0.00231 -0.33 -1.0788 -0.8717 3211839 TimTec1_004877 Cc1n[nH]c2nc3n(C)c(=O)n(C)c(=O)c3c(OC(=O)c4ccccc4)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N16 compound treatment 0.22 -0.00962 -1.33 0.224 -0.00131 -0.19 -1.0743 -0.7998 3086520 TimTec1_004878 CNC(=O)c1cccc(Oc2cccc(Cl)n2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N17 compound treatment 0.22 -0.00962 -1.33 0.22 -0.00531 -0.77 -1.4829 -0.9659 1658721 TimTec1_004879 S=C(NCCN1CCOCC1)NC2CCCc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N18 compound treatment 0.226 -0.00362 -0.5 0.235 0.00969 1.4 0.6353 0.4275 1394340 TimTec1_004880 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)c3ccccc3-c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N19 compound treatment 0.252 0.0224 3.09 0.254 0.0287 4.14 5.1159 0.9896 3211840 TimTec1_004881 NC(=O)C(Cc1ccccc1)NC(=O)c2ccc(Cl)cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N20 compound treatment 0.222 -0.00762 -1.05 0.222 -0.00331 -0.48 -1.0832 -0.9362 1014469 TimTec1_004882 CC(=O)Nc1ccccc1N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N21 compound treatment 0.22 -0.00962 -1.33 0.22 -0.00531 -0.77 -1.4829 -0.9659 3211841 TimTec1_004883 CC(C)N(Cc1ccccc1)C(=S)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N22 compound treatment 0.218 -0.0116 -1.61 0.221 -0.00431 -0.62 -1.5761 -0.915 3085427 TimTec1_004884 COc1ccccc1/C(=C\C)/C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N23 mock treatment 0.229 -6.25E-4 -0.09 0.225 -3.12E-4 -0.05 -0.093 -0.9542 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 N24 positive control 0.229 -6.25E-4 -0.09 0.226 6.88E-4 0.1 0.0092 0.0696 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O01 compound treatment 0.219 -0.0106 -1.47 0.23 0.00469 0.68 -0.5592 -0.3459 1506163 TimTec1_004885 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3c4OCN(CC=C)Cc4ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O02 compound treatment 0.222 -0.00762 -1.05 0.22 -0.00531 -0.77 -1.2875 -0.9879 1693531 TimTec1_004886 CC1(C)CC(CC(C)(C)N1)NC(=S)NC(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O03 compound treatment 0.262 0.0324 4.47 0.265 0.0397 5.73 7.2163 0.9925 3085432 TimTec1_004887 Clc1ccc(NN2C(=O)c3cccc4cc(Br)cc(C2=O)c34)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O04 compound treatment 0.236 0.00637 0.88 0.236 0.0107 1.54 1.7144 0.9646 1234657 TimTec1_004888 O=C(CSCc1ccc2nsnc2c1)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O05 compound treatment 0.223 -0.00662 -0.92 0.221 -0.00431 -0.62 -1.0877 -0.9824 3211842 TimTec1_004889 CCCN1C(=O)CCN(C(=O)C)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O06 compound treatment 0.222 -0.00762 -1.05 0.22 -0.00531 -0.77 -1.2875 -0.9879 1713735 TimTec1_004890 CC1(O)N(C2CC(C)(C)NC(C)(C)C2)C(=O)OC1(C)C3CC4CC3C=C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O07 compound treatment 0.218 -0.0116 -1.61 0.22 -0.00531 -0.77 -1.6782 -0.9429 3211843 TimTec1_004891 Cn1cnnc1SCc2c(Cl)cccc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O08 compound treatment 0.224 -0.00562 -0.78 0.222 -0.00331 -0.48 -0.8878 -0.9729 1260007 TimTec1_004892 CN1CCN(CC1)NC(=S)Nc2ccccc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O09 compound treatment 0.221 -0.00862 -1.19 0.22 -0.00531 -0.77 -1.3852 -0.9773 3085435 TimTec1_004893 NN(CCC(=O)NC1CCCCC1)C2=NS(=O)(=O)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O10 compound treatment 0.218 -0.0116 -1.61 0.214 -0.0113 -1.63 -2.2911 -1.0 3211844 TimTec1_004894 Clc1ccccc1C(=O)NCCOc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O11 compound treatment 0.229 -6.25E-4 -0.09 0.226 6.88E-4 0.1 0.0092 0.0696 1622091 TimTec1_004895 Cc1ccc(CNC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O12 compound treatment 0.349 0.119 16.49 0.331 0.106 15.27 22.4562 0.9993 1190874 TimTec1_004896 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(N4CCCCC4)c5ccccc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O13 compound treatment 0.218 -0.0116 -1.61 0.228 0.00269 0.39 -0.8611 -0.5212 1074879 TimTec1_004897 NC(=O)c1ccc(cc1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O14 compound treatment 0.28 0.0504 6.96 0.308 0.0827 11.94 13.3666 0.9669 1529201 TimTec1_004898 O=C1CSC(c2c(nn(c2N1)c3ccccc3)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O15 compound treatment 0.374 0.144 19.95 0.369 0.144 20.76 28.7797 0.9998 1372011 TimTec1_004899 OC(=O)C1(CCC(=O)NCc2ccccc2)CCC(=O)NC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O16 compound treatment 0.222 -0.00762 -1.05 0.225 -3.12E-4 -0.05 -0.7768 -0.7367 1451083 TimTec1_004900 Cc1cccc(NC(=O)CSc2nnc(CCC(=O)O)c(=O)n2N)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O17 compound treatment 0.395 0.165 22.85 0.411 0.186 26.82 35.1209 0.9968 1606306 TimTec1_004901 CC(=O)Nc1ccccc1c2nc3ccccc3nc2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O18 compound treatment 0.264 0.0344 4.75 0.249 0.0237 3.42 5.7774 0.9871 3211845 TimTec1_004902 Brc1ccc(NC(=O)CSCC(=O)Nc2cccc3ccccc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O19 compound treatment 0.222 -0.00762 -1.05 0.221 -0.00431 -0.62 -1.1853 -0.9686 1693543 TimTec1_004903 Cc1nonc1NC2(Nc3nonc3C)C(=O)c4ccccc4C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O20 compound treatment 0.453 0.223 30.86 0.467 0.242 34.91 46.5066 0.9981 1465796 TimTec1_004904 O=C(Sc1nc(c([nH]1)c2ccccc2)c3ccccc3)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O21 compound treatment 0.218 -0.0116 -1.61 0.216 -0.00931 -1.35 -2.0868 -0.9961 1609425 TimTec1_004905 CC(=O)Nc1ncc(CN2CCOCC2)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O22 compound treatment 0.285 0.0554 7.65 0.284 0.0587 8.48 11.4037 0.9987 1141664 TimTec1_004906 COc1ccc(cc1)S(=O)(=O)c2cc(NS(=O)(=O)c3ccccc3)cc(C(C)C)c2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O23 mock treatment 0.229 -6.25E-4 -0.09 0.224 -0.00131 -0.19 -0.1951 -0.9366 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 O24 positive control 0.226 -0.00362 -0.5 0.221 -0.00431 -0.62 -0.7946 -0.9941 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P01 compound treatment 0.218 -0.0116 -1.61 0.225 -3.12E-4 -0.05 -1.1675 -0.7267 3085443 TimTec1_004907 Nn1cnn2c(SCc3cccc(c3)C(F)(F)F)nnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P02 compound treatment 0.221 -0.00862 -1.19 0.221 -0.00431 -0.62 -1.283 -0.9542 3085445 TimTec1_004908 OC1(CC(=O)c2cccc(c2)n3cnnn3)C(=O)Nc4ccccc41 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P03 compound treatment 0.211 -0.0186 -2.57 0.212 -0.0133 -1.92 -3.1792 -0.9897 3211846 TimTec1_004909 NCCN1C(c2c(n[nH]c2C1=O)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P04 compound treatment 0.334 0.104 14.42 0.31 0.0847 12.23 18.846 0.9967 3211847 TimTec1_004910 Fc1ccc(NC=C2C(=O)NC(=O)NC2=O)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P05 compound treatment 0.221 -0.00862 -1.19 0.218 -0.00731 -1.06 -1.5894 -0.9982 3085513 TimTec1_004911 Cc1ccc(c(O)c1)C(O)(c2nc3ccccc3[nH]2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P06 compound treatment 0.289 0.0594 8.2 0.279 0.0537 7.75 11.2838 0.9996 1787981 TimTec1_004912 CCn1c2ccccc2c3cc(NC(=O)c4ccc(OC)c(OC)c4)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P07 compound treatment 0.277 0.0474 6.54 0.275 0.0497 7.18 9.703 0.9989 3085795 TimTec1_004913 O=C(CC(C(=O)c1ccccc1)n2cccn2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P08 compound treatment 0.253 0.0234 3.23 0.257 0.0317 4.58 5.52 0.9854 3211848 TimTec1_004914 CN(/N=C\1/CCN(C2CCCCC2)C1=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P09 compound treatment 0.222 -0.00762 -1.05 0.217 -0.00831 -1.2 -1.5939 -0.9979 3085796 TimTec1_004915 O=S(=O)(CCC#N)c1nnnn1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P10 compound treatment 0.237 0.00737 1.02 0.234 0.00869 1.25 1.6078 0.9947 1492454 TimTec1_004916 COC(=O)C1=C(N)C(=O)N(C1)c2ccc(cc2)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P11 compound treatment 0.214 -0.0156 -2.16 0.214 -0.0113 -1.63 -2.6818 -0.9906 3211849 TimTec1_004917 COc1ccc(cc1)C(=O)NC(Cc2ccccc2)C(=O)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P12 compound treatment 0.259 0.0294 4.06 0.254 0.0287 4.14 5.7997 0.9999 1062606 TimTec1_004918 N1=C(C1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P13 compound treatment 0.219 -0.0106 -1.47 0.218 -0.00731 -1.06 -1.7848 -0.987 3085797 TimTec1_004919 COc1cc(NS(=O)(=O)N2CCCC2)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P14 compound treatment 0.244 0.0144 1.99 0.248 0.0227 3.28 3.7215 0.9712 3211850 TimTec1_004920 O=C(NCCCc1ccccc1)C2c3ccccc3-c4ccccc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P15 compound treatment 0.233 0.00338 0.47 0.237 0.0117 1.69 1.5234 0.8698 3085798 TimTec1_004921 CNC(=O)C1=C(C)Nc2nc3ccccc3n2C1c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P16 compound treatment 0.221 -0.00862 -1.19 0.222 -0.00331 -0.48 -1.1809 -0.9197 1558273 TimTec1_004922 OC1C2CN3CC1(CN(C2)CC3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P17 compound treatment 0.243 0.0134 1.85 0.235 0.00969 1.4 2.296 0.9906 3211851 TimTec1_004923 O=C(Cc1ccccc1)Nc2nonc2NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P18 compound treatment 0.236 0.00637 0.88 0.241 0.0157 2.27 2.2251 0.9152 1454261 TimTec1_004924 CCCNC(=O)c1ccc(OC)c(OC(=O)c2ccccc2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P19 compound treatment 0.219 -0.0106 -1.47 0.221 -0.00431 -0.62 -1.4784 -0.9272 3211852 TimTec1_004925 CN(C)c1nc(N)nc(n1)C2CCCN2S(=O)(=O)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P20 compound treatment 0.218 -0.0116 -1.61 0.22 -0.00531 -0.77 -1.6782 -0.9429 3085799 TimTec1_004926 CS(=O)(=O)c1cccc(Cl)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P21 compound treatment 0.223 -0.00662 -0.92 0.225 -3.12E-4 -0.05 -0.6791 -0.7411 3085800 TimTec1_004927 CC1(C)C(OC(=O)C(C)(C)C1=O)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P22 compound treatment 0.22 -0.00962 -1.33 0.214 -0.0113 -1.63 -2.0957 -0.9948 1523811 TimTec1_004928 O=C(N1CCC2(Cc3ccccc3C2=O)CC1)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P23 mock treatment 0.228 -0.00162 -0.22 0.224 -0.00131 -0.19 -0.2928 -0.9965 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2076 P24 positive control 0.232 0.00238 0.33 0.221 -0.00431 -0.62 -0.2085 -0.2961 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A01 compound treatment 0.276 -0.00787 -1.09 0.269 -0.0201 -2.9 -2.8181 -0.9103 1644449 TimTec1_004929 COc1cc2CN(C)C(Cc3ccc(OC(=O)C)cc3)c2cc1OBr 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A02 compound treatment 0.282 -0.00187 -0.26 0.282 -0.00707 -1.02 -0.9041 -0.8588 3085801 TimTec1_004930 CCn1c(nc2ccccc12)c3nc4ccccc4n3CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A03 compound treatment 0.268 -0.0159 -2.19 0.276 -0.0131 -1.89 -2.8846 -0.9972 3211933 TimTec1_004931 CCOC(=O)/C=C(\C)/NC1CC(C)(C)NC(C)(C)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A04 compound treatment 0.297 0.0131 1.81 0.297 0.00793 1.15 2.0933 0.9754 3085802 TimTec1_004932 CO[C@H]1O[C@H](CO)C(=O)C(=C1N)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A05 compound treatment 0.274 -0.00987 -1.36 0.277 -0.0121 -1.74 -2.1963 -0.9926 3211934 TimTec1_004933 O=c1sc2ccccc2n1COc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A06 compound treatment 0.315 0.0311 4.3 0.319 0.0299 4.32 6.0987 1.0 1219039 TimTec1_004934 CN1CCN(Cc2c3ccccc3cc4ccccc24)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A07 compound treatment 0.286 0.00213 0.29 0.297 0.00793 1.15 1.0187 0.8609 3085803 TimTec1_004935 Cc1noc(C)c1C(=O)Nc2nnc(SCC(=O)O)s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A08 compound treatment 0.268 -0.0159 -2.19 0.268 -0.0211 -3.04 -3.7017 -0.987 1640299 TimTec1_004936 CN(Cc1ccc2OCOc2c1)C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A09 compound treatment 0.291 0.00713 0.99 0.293 0.00393 0.57 1.0986 0.9658 1531940 TimTec1_004937 OC(C(=O)c1ccccc1)c2c[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A10 compound treatment 0.265 -0.0189 -2.61 0.267 -0.0221 -3.19 -4.0969 -0.995 3211935 TimTec1_004938 Cn1nnnc1c2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A11 compound treatment 0.312 0.0281 3.89 0.316 0.0269 3.89 5.4992 1.0 1334202 TimTec1_004939 CC(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)c(C)oc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A12 compound treatment 0.281 -0.00287 -0.4 0.287 -0.00207 -0.3 -0.4911 -0.9903 1403452 TimTec1_004940 COc1ccccc1c2nn(CN(c3ccccc3)c4ccccc4)c(=S)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A13 compound treatment 0.263 -0.0209 -2.88 0.271 -0.0181 -2.61 -3.8837 -0.9988 1575737 TimTec1_004941 O=C(c1ccc2OCCCOc2c1)c3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A14 compound treatment 0.266 -0.0179 -2.47 0.264 -0.0251 -3.62 -4.3056 -0.9826 1152651 TimTec1_004942 O[C@@H](C1CC2CCN1CC2C=C)c3cnc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A15 compound treatment 0.287 0.00313 0.43 0.29 9.33E-4 0.13 0.4014 0.8854 1401869 TimTec1_004943 CC1(C)CC2(CCCN(CC#N)C2)CCO1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A16 compound treatment 0.274 -0.00987 -1.36 0.275 -0.0141 -2.03 -2.4006 -0.9811 1670175 TimTec1_004944 Cc1nc2c(sc3nc4CCCCc4c(c5ccco5)c32)c(=O)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A17 compound treatment 0.266 -0.0179 -2.47 0.27 -0.0191 -2.75 -3.6928 -0.9985 1247373 TimTec1_004945 Brc1ccnc(N2C(=O)c3ccccc3C2=O)c1Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A18 compound treatment 0.483 0.199 27.51 0.472 0.183 26.42 38.1374 0.9998 3211937 TimTec1_004946 Nc1c(sc2nc(ccc12)c3cccs3)C(=O)c4ccc(Br)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A19 compound treatment 0.266 -0.0179 -2.47 0.275 -0.0141 -2.03 -3.1821 -0.9953 3085804 TimTec1_004947 CC(=C)C(=O)N1C(COC1=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A20 compound treatment 0.264 -0.0199 -2.74 0.275 -0.0141 -2.03 -3.3775 -0.989 1254800 TimTec1_004948 CNc1nc(OC)cc(OC)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A21 compound treatment 0.504 0.22 30.41 0.478 0.189 27.29 40.8017 0.9985 3211938 TimTec1_004949 O=C(NCc1ccco1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A22 compound treatment 0.266 -0.0179 -2.47 0.273 -0.0161 -2.32 -3.3864 -0.9995 1033657 TimTec1_004950 CS(=O)(=O)c1nc2ccccc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A23 mock treatment 0.272 -0.0119 -1.64 0.278 -0.0111 -1.6 -2.2896 -0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 A24 positive control 0.265 -0.0189 -2.61 0.268 -0.0211 -3.04 -3.9948 -0.997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B01 compound treatment 0.282 -0.00187 -0.26 0.289 -6.67E-5 -0.01 -0.1892 -0.733 3211939 TimTec1_004951 CC(C)(C)C(=O)Nc1nccs1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B02 compound treatment 0.328 0.0441 6.1 0.336 0.0469 6.78 9.105 0.9986 3211940 TimTec1_004952 O=S(=O)(/N=C(\Nc1cccc2ccccc12)/c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B03 compound treatment 0.283 -8.67E-4 -0.12 0.289 -6.67E-5 -0.01 -0.0915 -0.7615 1143395 TimTec1_004953 CN(C)c1nc2n(C)c(=O)[nH]c(=O)c2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B04 compound treatment 0.278 -0.00587 -0.81 0.288 -0.00107 -0.15 -0.682 -0.8267 3085810 TimTec1_004954 CCOC(=O)c1cn(nc1C(F)(F)F)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B05 compound treatment 0.3 0.0161 2.23 0.307 0.0179 2.59 3.4077 0.9972 3211941 TimTec1_004955 CCc1[o+]c(cc2CCCCc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B06 compound treatment 0.288 0.00413 0.57 0.295 0.00593 0.86 1.0098 0.9805 1673469 TimTec1_004956 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B07 compound treatment 0.393 0.109 15.08 0.399 0.11 15.88 21.8894 0.9997 3211942 TimTec1_004957 O=C/1CCCC\C1=C\Nc2cccc(N/C=C\3/CCCCC3=O)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B08 compound treatment 0.284 1.33E-4 0.02 0.288 -0.00107 -0.15 -0.0959 -0.6182 1541165 TimTec1_004958 Cc1nonc1NC(=O)Nc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B09 compound treatment 0.29 0.00613 0.85 0.295 0.00593 0.86 1.2052 1.0 1429667 TimTec1_004959 COc1cccc(C(N2CCCC2)c3cc4OCOc4cc3O)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B10 compound treatment 0.292 0.00813 1.12 0.298 0.00893 1.29 1.707 0.9976 3085814 TimTec1_004960 CC(=O)Nc1sc(C)c(C)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B11 compound treatment 0.284 1.33E-4 0.02 0.285 -0.00407 -0.59 -0.4023 -0.6846 1366449 TimTec1_004961 CN(C)c1ccc(cc1)C2CC(C)(Oc3cc4OCOc4cc23)N5CCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B12 compound treatment 0.302 0.0181 2.51 0.318 0.0289 4.18 4.7266 0.97 3085816 TimTec1_004962 CC1=NNC(=O)C1C(C(C#N)C#N)c2ccccc2F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B13 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 1019517 TimTec1_004963 COc1cc(cc(OC)c1O)C2C3C(COC3=O)Cc4c(O)c5OCOc5cc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B14 compound treatment 0.288 0.00413 0.57 0.295 0.00593 0.86 1.0098 0.9805 1563233 TimTec1_004964 CCSc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc3ccc(C)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B15 compound treatment 0.28 -0.00387 -0.53 0.282 -0.00707 -1.02 -1.0995 -0.9544 3085858 TimTec1_004965 COc1cnc(SC)n(C)c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B16 compound treatment 0.29 0.00613 0.85 0.299 0.00993 1.43 1.6137 0.9684 1621047 TimTec1_004966 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc(Cl)cc3Cl)c(Br)nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B17 compound treatment 0.282 -0.00187 -0.26 0.289 -6.67E-5 -0.01 -0.1892 -0.733 1547656 TimTec1_004967 CCOc1nc2ccccc2c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B18 compound treatment 0.364 0.0801 11.07 0.374 0.0849 12.27 16.503 0.9987 1446595 TimTec1_004968 CC(C)c1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B19 compound treatment 0.279 -0.00487 -0.67 0.282 -0.00707 -1.02 -1.1972 -0.9795 2747 TimTec1_004969 Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B20 compound treatment 0.6 0.316 43.67 0.601 0.312 45.06 62.7427 0.9999 1295276 TimTec1_004970 NC(=S)c1[nH]nc2c1[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B21 compound treatment 0.278 -0.00587 -0.81 0.281 -0.00807 -1.17 -1.397 -0.9843 1170984 TimTec1_004971 Cc1ccc(SC(CC(=O)c2ccc(cc2)C(C)(C)C)C(=O)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B22 compound treatment 0.323 0.0391 5.41 0.333 0.0439 6.35 8.3101 0.9968 3085864 TimTec1_004972 CCCCC1SC(=NNC1=O)/N=C/c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B23 mock treatment 0.279 -0.00487 -0.67 0.291 0.00193 0.28 -0.2779 -0.3818 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 B24 positive control 0.279 -0.00487 -0.67 0.287 -0.00207 -0.3 -0.6865 -0.9332 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C01 compound treatment 0.29 0.00613 0.85 0.296 0.00693 1.0 1.3073 0.9965 1262842 TimTec1_004973 CCOC(=O)C1(CCN(c2ccccc2C1=O)S(=O)(=O)c3ccc(C)cc3)C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C02 compound treatment 0.283 -8.67E-4 -0.12 0.289 -6.67E-5 -0.01 -0.0915 -0.7615 1630883 TimTec1_004974 Cn1c(nc2ccccc12)P(=O)(C)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C03 compound treatment 0.283 -8.67E-4 -0.12 0.287 -0.00207 -0.3 -0.2957 -0.9195 3211943 TimTec1_004975 CCc1cccc(NC(=O)OC2CCN(C)CC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C04 compound treatment 0.285 0.00113 0.16 0.296 0.00693 1.0 0.8189 0.8078 3085867 TimTec1_004976 Oc1ccccc1/N=C/c2ccncc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C05 compound treatment 0.276 -0.00787 -1.09 0.288 -0.00107 -0.15 -0.8774 -0.7994 1684419 TimTec1_004977 CC(=O)Nc1ccc2n(CC=C)c(=O)sc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C06 compound treatment 0.284 1.33E-4 0.02 0.288 -0.00107 -0.15 -0.0959 -0.6182 3085869 TimTec1_004978 CN1CCN(Cc2c(Cl)cccc2Cl)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C07 compound treatment 0.336 0.0521 7.2 0.341 0.0519 7.5 10.3972 0.9998 1544605 TimTec1_004979 Cc1ccc(F)c2[nH]cc3c(=O)n(nc3c12)c4ccccc4Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C08 compound treatment 0.282 -0.00187 -0.26 0.29 9.33E-4 0.13 -0.087 -0.299 1692460 TimTec1_004980 CSc1ccc(CN2CCOCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C09 compound treatment 0.355 0.0711 9.83 0.356 0.0669 9.67 13.7853 1.0 1697399 TimTec1_004981 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)ON4C(=O)CCC4=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C10 compound treatment 0.29 0.00613 0.85 0.289 -6.67E-5 -0.01 0.5923 0.699 1553247 TimTec1_004982 Nc1nc(c(Cl)s1)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C11 compound treatment 0.291 0.00713 0.99 0.299 0.00993 1.43 1.7114 0.9832 1170357 TimTec1_004983 CC(C)(C)OC(=O)N1CCCC1C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc5OCCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C12 compound treatment 0.334 0.0501 6.93 0.338 0.0489 7.07 9.8954 0.9999 1143084 TimTec1_004984 O=C(CSCc1c[nH]c2ccccc12)Nc3ccc4ccccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C13 compound treatment 0.286 0.00213 0.29 0.292 0.00293 0.42 0.508 0.9843 1113621 TimTec1_004985 S=C(N1CCOCC1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C14 compound treatment 0.279 -0.00487 -0.67 0.276 -0.0131 -1.89 -1.81 -0.9034 3211944 TimTec1_004986 OC[C@H]1[C@@H](C[C@@H]2OC(=O)C[C@H]12)OC(=O)c3ccc(cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C15 compound treatment 0.281 -0.00287 -0.4 0.278 -0.0111 -1.6 -1.4104 -0.8564 1673684 TimTec1_004987 COc1nc(nc(n1)N2CCc3ccccc23)N4CCc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C16 compound treatment 0.299 0.0151 2.09 0.305 0.0159 2.3 3.1057 0.9989 3085875 TimTec1_004988 CCc1nc(SC)c(C#N)c2CCCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C17 compound treatment 0.289 0.00513 0.71 0.289 -6.67E-5 -0.01 0.4947 0.6974 1436730 TimTec1_004989 CC1(C)CC(=O)C(C(=C1)O)C2(O)C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C18 compound treatment 0.284 1.33E-4 0.02 0.285 -0.00407 -0.59 -0.4023 -0.6846 1271503 TimTec1_004990 COc1ccc(OC)c(c1)C2C(=C(N)Oc3cc(C)oc(=O)c23)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C19 compound treatment 0.487 0.203 28.06 0.467 0.178 25.7 38.0174 0.999 3085916 TimTec1_004991 CC[n+]1ccc(/C=C/c2ccc(OC)c(OC)c2OC)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C20 compound treatment 0.277 -0.00687 -0.95 0.281 -0.00807 -1.17 -1.4947 -0.9948 3085918 TimTec1_004992 Nc1nc(OCC(F)(F)F)cc(n1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C21 compound treatment 0.423 0.139 19.22 0.43 0.141 20.36 27.9863 0.9996 3211998 TimTec1_004993 CC1CCN(CC1)C(=O)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C22 compound treatment 0.292 0.00813 1.12 0.295 0.00593 0.86 1.4005 0.9911 3085922 TimTec1_004994 Cc1nc2ccccc2c(=O)n1/N=C/c3ccc4ncccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C23 mock treatment 0.282 -0.00187 -0.26 0.289 -6.67E-5 -0.01 -0.1892 -0.733 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 C24 positive control 0.283 -8.67E-4 -0.12 0.291 0.00193 0.28 0.1128 0.3713 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D01 compound treatment 0.287 0.00313 0.43 0.285 -0.00407 -0.59 -0.1093 -0.1498 1018493 TimTec1_004995 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D02 compound treatment 0.282 -0.00187 -0.26 0.288 -0.00107 -0.15 -0.2913 -0.9697 1571869 TimTec1_004996 Cc1ccc(cc1)S(=O)(=O)NC(=O)SC#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D03 compound treatment 0.321 0.0371 5.13 0.323 0.0339 4.9 7.0934 0.9997 1513997 TimTec1_004997 Cc1cccc(Oc2ncc(F)c(Oc3cccc(C)c3)n2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D04 compound treatment 0.292 0.00813 1.12 0.287 -0.00207 -0.3 0.5834 0.5018 1365828 TimTec1_004998 CSc1nc2NC(=CC(c3ccccc3)n2n1)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D05 compound treatment 0.351 0.0671 9.27 0.344 0.0549 7.93 12.1689 0.997 3085925 TimTec1_004999 CCc1[o+]c(cc2cc(OC)c(OC)cc12)c3ccc(OC)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D06 compound treatment 0.324 0.0401 5.54 0.308 0.0189 2.73 5.8544 0.947 1921582 TimTec1_005000 Cc1cc(C)n(n1)C(=O)c2ccc(cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D07 compound treatment 0.298 0.0141 1.95 0.298 0.00893 1.29 2.2931 0.9798 3211999 TimTec1_005001 O=C/1CCCC\C1=C\Nc2ccc(N/C=C\3/CCCCC3=O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D08 compound treatment 0.28 -0.00387 -0.53 0.286 -0.00307 -0.44 -0.691 -0.9957 1174633 TimTec1_005002 CC(NC(=O)c1cccc(N)c1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D09 compound treatment 0.295 0.0111 1.54 0.302 0.0129 1.87 2.4086 0.9953 1210964 TimTec1_005003 COc1ccc(cc1)C(C)c2cc3OCOc3cc2OCC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D10 compound treatment 0.278 -0.00587 -0.81 0.284 -0.00507 -0.73 -1.0906 -0.9987 3212000 TimTec1_005004 Clc1ccc(NC(=O)c2cccs2)nc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D11 compound treatment 0.308 0.0241 3.33 0.3 0.0109 1.58 3.4742 0.9417 1124331 TimTec1_005005 CN(C)c1ccc(cc1)C(N2CCCCC2)c3cc4OCOc4cc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D12 compound treatment 0.282 -0.00187 -0.26 0.284 -0.00507 -0.73 -0.6999 -0.9019 1007160 TimTec1_005006 NC(=N)Nc1nc2ccccc2[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D13 compound treatment 0.353 0.0691 9.55 0.362 0.0729 10.53 14.2028 0.9988 3085929 TimTec1_005007 Cn1c(=O)n(C)c2nc([nH]c2c1=O)[n+]3ccc(cc3)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D14 compound treatment 0.291 0.00713 0.99 0.298 0.00893 1.29 1.6093 0.9911 1272092 TimTec1_005008 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc4ccccc4c3)c(S)nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D15 compound treatment 0.27 -0.0139 -1.92 0.277 -0.0121 -1.74 -2.5871 -0.9989 1371696 TimTec1_005009 OC(=O)Cn1ccsc1=N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D16 compound treatment 0.282 -0.00187 -0.26 0.284 -0.00507 -0.73 -0.6999 -0.9019 3085931 TimTec1_005010 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccccc2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D17 compound treatment 0.288 0.00413 0.57 0.285 -0.00407 -0.59 -0.0116 -0.0141 1391232 TimTec1_005011 CCOc1nc2ccccc2c(=O)n1CCO 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D18 compound treatment 0.311 0.0271 3.75 0.315 0.0259 3.75 5.2994 1.0 1600779 TimTec1_005012 NC(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D19 compound treatment 0.276 -0.00787 -1.09 0.278 -0.0111 -1.6 -1.8988 -0.9823 3085934 TimTec1_005013 Cn1cnnc1SC/C=C/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D20 compound treatment 0.339 0.0551 7.62 0.391 0.102 14.72 15.7972 0.9529 3212001 TimTec1_005014 N(=c/1\[nH]c2c(ccc3ccccc23)s1)\c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D21 compound treatment 0.277 -0.00687 -0.95 0.277 -0.0121 -1.74 -1.9033 -0.9591 1597367 TimTec1_005015 OC(=O)C(CC(=O)c1ccc(Cl)cc1)SCc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D22 compound treatment 0.451 0.167 23.09 0.426 0.137 19.78 30.313 0.997 3212002 TimTec1_005016 N1N=C(SC=C1c2ccccc2)/N=C/c3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D23 mock treatment 0.285 0.00113 0.16 0.287 -0.00207 -0.3 -0.1004 -0.2978 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 D24 positive control 0.285 0.00113 0.16 0.289 -6.67E-5 -0.01 0.1039 0.6624 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E01 compound treatment 0.319 0.0351 4.85 0.314 0.0249 3.6 5.9787 0.9892 1071315 TimTec1_005017 COc1ccc2c3CCCC(=O)c3ccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E02 compound treatment 0.455 0.171 23.64 0.452 0.163 23.53 33.3594 1.0 1454628 TimTec1_005018 Oc1ccc(C(=O)COc2ccccc2)c(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E03 compound treatment 0.295 0.0111 1.54 0.297 0.00793 1.15 1.8979 0.9895 3085938 TimTec1_005019 CCOC(=O)Nc1nc2c(Cl)cccc2s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E04 compound treatment 0.28 -0.00387 -0.53 0.284 -0.00507 -0.73 -0.8952 -0.988 1030338 TimTec1_005020 COC(=O)c1nc[nH]c1C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E05 compound treatment 0.281 -0.00287 -0.4 0.283 -0.00607 -0.88 -0.8997 -0.9356 3085974 TimTec1_005021 CCOC(=O)n1c(=O)sc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E06 compound treatment 0.28 -0.00387 -0.53 0.286 -0.00307 -0.44 -0.691 -0.9957 3085976 TimTec1_005022 CN1CCN(CC2CCC=CC2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E07 compound treatment 0.281 -0.00287 -0.4 0.287 -0.00207 -0.3 -0.4911 -0.9903 1140829 TimTec1_005023 CN(C)S(=O)(=O)c1ccc(C#N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E08 compound treatment 0.282 -0.00187 -0.26 0.289 -6.67E-5 -0.01 -0.1892 -0.733 1363499 TimTec1_005024 CCCN(CCO)CC1CCC=CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E09 compound treatment 0.417 0.133 18.39 0.377 0.0879 12.7 21.9869 0.9837 1427526 TimTec1_005025 O=c1c(Oc2ccccc2)coc3cc(OCc4ccccc4)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E10 compound treatment 0.279 -0.00487 -0.67 0.284 -0.00507 -0.73 -0.9929 -0.9991 1637231 TimTec1_005026 COC1(CCCC2(CCC1)C(=O)O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E11 compound treatment 0.336 0.0521 7.2 0.304 0.0149 2.16 6.6181 0.8803 1442714 TimTec1_005027 CCOC(=O)c1ccc(o1)c2coc3cc(O)cc(O)c3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E12 compound treatment 0.299 0.0151 2.09 0.307 0.0179 2.59 3.31 0.9944 1234769 TimTec1_005028 COc1ccc(cc1)c2cc(NC(=O)Nc3ccccc3)n(n2)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E13 compound treatment 0.292 0.00813 1.12 0.317 0.0279 4.03 3.6476 0.8709 1381033 TimTec1_005029 COc1cc(Cl)cc(C(=O)O)c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E14 compound treatment 0.362 0.0781 10.79 0.359 0.0699 10.1 14.7755 0.9995 1056436 TimTec1_005030 CC(C)c1nc2nc(N)nc(N)c2nc1C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E15 compound treatment 0.277 -0.00687 -0.95 0.282 -0.00707 -1.02 -1.3926 -0.9993 1074483 TimTec1_005031 CCN(C(=O)Nc1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E16 compound treatment 0.375 0.0911 12.59 0.383 0.0939 13.57 18.4968 0.9993 3212003 TimTec1_005032 Cc1s/c(=N/c2ccccc2)/[nH]c1c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E17 compound treatment 0.335 0.0511 7.06 0.328 0.0389 5.62 8.9717 0.9936 3212004 TimTec1_005033 C(=N/c1cc(nn1c2ccccc2)c3ccccc3)\c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E18 compound treatment 0.282 -0.00187 -0.26 0.284 -0.00507 -0.73 -0.6999 -0.9019 3085984 TimTec1_005034 COc1ccc(/C=C/2\C(=NC(=NC2=O)S)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E19 compound treatment 0.278 -0.00587 -0.81 0.278 -0.0111 -1.6 -1.7034 -0.9504 3212005 TimTec1_005035 CCc1ccc(NC(=O)CSc2nncn2C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E20 compound treatment 0.279 -0.00487 -0.67 0.28 -0.00907 -1.31 -1.4015 -0.952 3085985 TimTec1_005036 Cc1cc(nc(N)n1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E21 compound treatment 0.4 0.116 16.04 0.397 0.108 15.59 22.3689 0.9999 3212006 TimTec1_005037 Cc1ccc(cc1)C(=O)N/C(=C\C=C/c2ccccc2)/C(=O)NCC3CCCO3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E22 compound treatment 0.352 0.0681 9.41 0.348 0.0589 8.51 12.6751 0.9987 3085988 TimTec1_005038 Oc1ccc(/C=N\C2c3ccccc3-c4ccccc24)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E23 mock treatment 0.281 -0.00287 -0.4 0.288 -0.00107 -0.15 -0.389 -0.9154 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 E24 positive control 0.285 0.00113 0.16 0.29 9.33E-4 0.13 0.206 0.9972 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F01 compound treatment 0.332 0.0481 6.65 0.334 0.0449 6.49 9.2915 0.9999 3212007 TimTec1_005039 C[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F02 compound treatment 0.275 -0.00887 -1.22 0.286 -0.00307 -0.44 -1.1794 -0.9054 3085989 TimTec1_005040 Cn1c(=O)[nH]c(=O)c2n3CCCC(c3nc12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F03 compound treatment 0.283 -8.67E-4 -0.12 0.287 -0.00207 -0.3 -0.2957 -0.9195 3212008 TimTec1_005041 Clc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F04 compound treatment 0.319 0.0351 4.85 0.324 0.0349 5.05 7.0001 0.9998 1188459 TimTec1_005042 OC(CN(Cc1ccccc1)Cc2ccccc2)Cn3c4ccccc4c5ccccc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F05 compound treatment 0.34 0.0561 7.75 0.345 0.0559 8.08 11.1965 0.9998 3085992 TimTec1_005043 COC(=O)C(Cc1c[nH]c2ccccc12)/N=C/c3cc(Cl)cc(Cl)c3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F06 compound treatment 0.292 0.00813 1.12 0.296 0.00693 1.0 1.5027 0.9984 1464296 TimTec1_005044 CCCOC(=O)c1c(N)sc2CCCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F07 compound treatment 0.28 -0.00387 -0.53 0.288 -0.00107 -0.15 -0.4867 -0.8754 3085994 TimTec1_005045 CC1(C)CC(=O)C/C(=N\CC(=O)O)/C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F08 compound treatment 0.332 0.0481 6.65 0.328 0.0389 5.62 8.6786 0.9965 3212009 TimTec1_005046 COc1cccc(c1)c2nnc(o2)c3ccc(NC(=O)C(F)(F)F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F09 compound treatment 0.279 -0.00487 -0.67 0.283 -0.00607 -0.88 -1.0951 -0.9914 1692415 TimTec1_005047 COc1ccccc1C(C2=C(O)COC2=O)c3cc4OCOc4cc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F10 compound treatment 0.325 0.0411 5.68 0.338 0.0489 7.07 9.0162 0.9941 1261046 TimTec1_005048 O=C(Nc1nccs1)c2ccccc2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F11 compound treatment 0.324 0.0401 5.54 0.334 0.0449 6.49 8.5099 0.9969 1427389 TimTec1_005049 Oc1cc2OCOc2cc1C(Nc3ccccn3)c4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F12 compound treatment 0.339 0.0551 7.62 0.353 0.0639 9.23 11.9159 0.9954 1182617 TimTec1_005050 CC(C)(C)C(=O)C1C2CCC1C(O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F13 compound treatment 0.273 -0.0109 -1.5 0.285 -0.00407 -0.59 -1.4769 -0.9162 1471843 TimTec1_005051 Cn1c(SCC(=O)OCC(=O)c2ccc(Br)cc2)nc3n(C)c(=O)[nH]c(=O)c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F14 compound treatment 0.279 -0.00487 -0.67 0.274 -0.0151 -2.18 -2.0143 -0.8843 1227820 TimTec1_005052 CC1CCN(CC1)C(=O)COc2ccc(Br)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F15 compound treatment 0.278 -0.00587 -0.81 0.274 -0.0151 -2.18 -2.112 -0.9094 1067946 TimTec1_005053 Cc1nnc(o1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F16 compound treatment 0.289 0.00513 0.71 0.297 0.00793 1.15 1.3118 0.9734 3212010 TimTec1_005054 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F17 compound treatment 0.283 -8.67E-4 -0.12 0.283 -0.00607 -0.88 -0.7043 -0.7963 1743351 TimTec1_005055 CCOC(=O)CNc1nc(N)n[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F18 compound treatment 0.308 0.0241 3.33 0.295 0.00593 0.86 2.9636 0.8609 3212069 TimTec1_005056 Sc1nnc2c3cc(Br)ccc3n(CC=C)c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F19 compound treatment 0.276 -0.00787 -1.09 0.285 -0.00407 -0.59 -1.1838 -0.9583 3086039 TimTec1_005057 OC(=O)c1ccc(Sc2ccccn2)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F20 compound treatment 0.445 0.161 22.26 0.443 0.154 22.23 31.4632 1.0 3212070 TimTec1_005058 CC1SC(=NNC1=O)/N=C/c2ccc(cc2)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F21 compound treatment 0.275 -0.00887 -1.22 0.278 -0.0111 -1.6 -1.9965 -0.9914 1338088 TimTec1_005059 Cc1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F22 compound treatment 0.278 -0.00587 -0.81 0.281 -0.00807 -1.17 -1.397 -0.9843 3212071 TimTec1_005060 Cc1c(/N=c/2\scc(c3ccccc3)n2c4ccccc4)c(=O)n(c5ccccc5)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F23 mock treatment 0.281 -0.00287 -0.4 0.288 -0.00107 -0.15 -0.389 -0.9154 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 F24 positive control 0.286 0.00213 0.29 0.29 9.33E-4 0.13 0.3037 0.9372 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G01 compound treatment 0.291 0.00713 0.99 0.295 0.00593 0.86 1.3029 0.9976 3086042 TimTec1_005061 CCOC(=O)C1=C(O)C(=O)N(C1)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G02 compound treatment 0.28 -0.00387 -0.53 0.284 -0.00507 -0.73 -0.8952 -0.988 3212072 TimTec1_005062 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2)C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G03 compound treatment 0.282 -0.00187 -0.26 0.282 -0.00707 -1.02 -0.9041 -0.8588 1400641 TimTec1_005063 C=CCON1C(=O)C2C3OC(C=C3)C2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G04 compound treatment 0.283 -8.67E-4 -0.12 0.287 -0.00207 -0.3 -0.2957 -0.9195 3212073 TimTec1_005064 C[N+](C)(C)[C@H]1C(O)O[C@@H]2C(O)CO[C@H]12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G05 compound treatment 0.287 0.00313 0.43 0.282 -0.00707 -1.02 -0.4157 -0.3749 1411352 TimTec1_005065 C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)C4(OCCO4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G06 compound treatment 0.284 1.33E-4 0.02 0.282 -0.00707 -1.02 -0.7088 -0.6942 3212074 TimTec1_005066 CN1CCN(Cc2ccc[nH]2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G07 compound treatment 0.318 0.0341 4.72 0.315 0.0259 3.75 5.9832 0.9935 3086046 TimTec1_005067 COc1ccc(cc1)c2nc3ccsc3c(=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G08 compound treatment 0.277 -0.00687 -0.95 0.284 -0.00507 -0.73 -1.1883 -0.9918 1405970 TimTec1_005068 CN(C)CCN(CC1CC2CC1C=C2)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G09 compound treatment 0.279 -0.00487 -0.67 0.283 -0.00607 -0.88 -1.0951 -0.9914 1084368 TimTec1_005069 OC(=O)C1CSC2(CCCCC2)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G10 compound treatment 0.345 0.0611 8.45 0.344 0.0549 7.93 11.5828 0.9995 1144864 TimTec1_005070 CCN1C(=O)c2cccc3c(NC(=O)C)ccc1c23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G11 compound treatment 0.274 -0.00987 -1.36 0.278 -0.0111 -1.6 -2.0942 -0.9969 3212075 TimTec1_005071 Cc1[nH]cnc1C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G12 compound treatment 0.291 0.00713 0.99 0.295 0.00593 0.86 1.3029 0.9976 1717981 TimTec1_005072 Oc1ccc(=O)n(CN(c2ccccc2)c3ccccc3)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G13 compound treatment 0.276 -0.00787 -1.09 0.284 -0.00507 -0.73 -1.286 -0.9815 1174597 TimTec1_005073 CCc1cc2OCCOc2cc1C(=O)CCN3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G14 compound treatment 0.278 -0.00587 -0.81 0.275 -0.0141 -2.03 -2.0098 -0.9188 3086051 TimTec1_005074 CC1CC(C)(C)N=C(O1)C(=C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G15 compound treatment 0.289 0.00513 0.71 0.29 9.33E-4 0.13 0.5968 0.8267 1409343 TimTec1_005075 O=C1N(CNN2CCCc3ccccc23)C(=O)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G16 compound treatment 0.275 -0.00887 -1.22 0.282 -0.00707 -1.02 -1.5879 -0.9959 1629224 TimTec1_005076 CSc1ccc(cc1)c2[nH]c(=N)sc2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G17 compound treatment 0.298 0.0141 1.95 0.298 0.00893 1.29 2.2931 0.9798 1378559 TimTec1_005077 CCN(CC)c1nc(NC(C)(C)C)nc(NC(C)(C)C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G18 compound treatment 0.283 -8.67E-4 -0.12 0.285 -0.00407 -0.59 -0.5 -0.8341 1733553 TimTec1_005078 Oc1nc2CCCc2c(=O)n1C3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G19 compound treatment 0.293 0.00913 1.26 0.284 -0.00507 -0.73 0.3747 0.2569 3086099 TimTec1_005079 Clc1ccc(SCC(=O)Nc2cccc(Cl)c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G20 compound treatment 0.279 -0.00487 -0.67 0.272 -0.0171 -2.47 -2.2186 -0.8682 1367022 TimTec1_005080 Oc1ccccc1OCC(=O)Nc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G21 compound treatment 0.277 -0.00687 -0.95 0.28 -0.00907 -1.31 -1.5968 -0.9875 3212076 TimTec1_005081 O=C(NCC1CCCO1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G22 compound treatment 0.276 -0.00787 -1.09 0.278 -0.0111 -1.6 -1.8988 -0.9823 3086101 TimTec1_005082 O=S(=O)(c1ccc(/N=C\c2ccncc2)cc1)c3ccc(/N=C\c4ccncc4)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G23 mock treatment 0.284 1.33E-4 0.02 0.287 -0.00207 -0.3 -0.1981 -0.6622 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 G24 positive control 0.283 -8.67E-4 -0.12 0.289 -6.67E-5 -0.01 -0.0915 -0.7615 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H01 compound treatment 0.379 0.0951 13.14 0.377 0.0879 12.7 18.2747 0.9999 3212077 TimTec1_005083 CC[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H02 compound treatment 0.286 0.00213 0.29 0.287 -0.00207 -0.3 -0.0027 -0.0064 1673284 TimTec1_005084 CC(=C)c1cccc(c1)C(C)(C)NC(=O)NCC2CCCO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H03 compound treatment 0.288 0.00413 0.57 0.29 9.33E-4 0.13 0.4991 0.8507 3086104 TimTec1_005085 Clc1nc(nc2sc3CCCCc3c12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H04 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 3212078 TimTec1_005086 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)/c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H05 compound treatment 0.291 0.00713 0.99 0.291 0.00193 0.28 0.8943 0.8731 1072337 TimTec1_005087 CCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H06 compound treatment 0.34 0.0561 7.75 0.348 0.0589 8.51 11.5029 0.9989 1560027 TimTec1_005088 Cc1ccccc1C(=O)Nc2cc3CCCCc3s2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H07 compound treatment 0.285 0.00113 0.16 0.284 -0.00507 -0.73 -0.4068 -0.5435 3086107 TimTec1_005089 OC(=O)c1ccc(/N=C/c2cccnc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H08 compound treatment 0.311 0.0271 3.75 0.307 0.0179 2.59 4.4823 0.9837 1735547 TimTec1_005090 O=C1CCC(=O)N1c2ccc3c(c2)oc4ccccc43 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H09 compound treatment 0.278 -0.00587 -0.81 0.283 -0.00607 -0.88 -1.1927 -0.9992 1148656 TimTec1_005091 COc1ccccc1C(C2=C(COC2=O)OC(=O)C)c3cc4OCOc4cc3OC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H10 compound treatment 0.297 0.0131 1.81 0.3 0.0109 1.58 2.3997 0.9976 3212079 TimTec1_005092 Fc1ccccc1NC(=O)CSCC(=O)Nc2ccc3ccccc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H11 compound treatment 0.298 0.0141 1.95 0.294 0.00493 0.71 1.8845 0.9067 1232879 TimTec1_005093 COc1ccc(cc1)C(N2CCOCC2)c3cc4OCOc4cc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H12 compound treatment 0.276 -0.00787 -1.09 0.28 -0.00907 -1.31 -1.6945 -0.9957 1704797 TimTec1_005094 O=C(CCc1ccccc1)N2CCN(CC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H13 compound treatment 0.275 -0.00887 -1.22 0.283 -0.00607 -0.88 -1.4858 -0.9865 1531317 TimTec1_005095 CCCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H14 compound treatment 0.31 0.0261 3.61 0.314 0.0249 3.6 5.0996 1.0 1213903 TimTec1_005096 CC(C)(C)c1ccccc1OCC(=O)Nc2ccc(OCc3ccccc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H15 compound treatment 0.34 0.0561 7.75 0.341 0.0519 7.5 10.7879 0.9999 3212080 TimTec1_005097 CSc1nc(N)c(C#N)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H16 compound treatment 0.286 0.00213 0.29 0.284 -0.00507 -0.73 -0.3091 -0.3918 1603630 TimTec1_005098 CCOC(=O)N(c1ccc(OC)cc1)S(=O)(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H17 compound treatment 0.304 0.0201 2.78 0.298 0.00893 1.29 2.8792 0.939 1625154 TimTec1_005099 CCn1c(=O)c(C(=O)NC)c(O)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H18 compound treatment 0.284 1.33E-4 0.02 0.284 -0.00507 -0.73 -0.5045 -0.6891 3212081 TimTec1_005100 COc1ccc(c2n[nH]c(C)c2Oc3ccccc3)c(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H19 compound treatment 0.308 0.0241 3.33 0.31 0.0209 3.02 4.4956 0.9988 1424497 TimTec1_005101 CCOC(=O)C1=C(C)NC(=O)NC1c2c(Cl)nc3c(C)cccn3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H20 compound treatment 0.333 0.0491 6.79 0.336 0.0469 6.78 9.5934 1.0 3212082 TimTec1_005102 COc1ccc(/C=N/C2=NNC(=O)CS2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H21 compound treatment 0.274 -0.00987 -1.36 0.278 -0.0111 -1.6 -2.0942 -0.9969 1547308 TimTec1_005103 CC(C)(C)c1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H22 compound treatment 0.376 0.0921 12.73 0.38 0.0909 13.13 18.2881 0.9999 3212083 TimTec1_005104 COc1ccc(/C=N/C2=NNC(=CS2)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H23 mock treatment 0.286 0.00213 0.29 0.287 -0.00207 -0.3 -0.0027 -0.0064 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 H24 positive control 0.283 -8.67E-4 -0.12 0.292 0.00293 0.42 0.2149 0.4882 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I01 compound treatment 0.29 0.00613 0.85 0.288 -0.00107 -0.15 0.4902 0.5692 1210543 TimTec1_005105 O=C(c1ccccc1)C2(OCCCCO2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I02 compound treatment 0.363 0.0791 10.93 0.367 0.0779 11.26 15.6903 0.9999 3212084 TimTec1_005106 CN1C(=O)/C(=C\NC(=O)C)/C(=C(C#N)C1=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I03 compound treatment 0.301 0.0171 2.37 0.31 0.0209 3.02 3.8118 0.9927 1253003 TimTec1_005107 COC(C)OC(=O)Cn1c(=O)sc2cccc(Cl)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I04 compound treatment 0.276 -0.00787 -1.09 0.284 -0.00507 -0.73 -1.286 -0.9815 1054992 TimTec1_005108 Brc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I05 compound treatment 0.35 0.0661 9.14 0.344 0.0549 7.93 12.0712 0.9975 3212085 TimTec1_005109 Cc1ccccc1Nc2cc(C)c(C#N)c3nc4ccccc4n23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I06 compound treatment 0.312 0.0281 3.89 0.323 0.0339 4.9 6.2142 0.9934 1286333 TimTec1_005110 CCn1c2ccccc2c3cc(CN(C)Cc4ccccc4)ccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I07 compound treatment 0.328 0.0441 6.1 0.342 0.0529 7.65 9.7178 0.9937 1318051 TimTec1_005111 COc1ccc2OCc3ccccc3C(O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I08 compound treatment 0.275 -0.00887 -1.22 0.286 -0.00307 -0.44 -1.1794 -0.9054 1348090 TimTec1_005112 CN(C)CCN(Cc1ccsc1)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I09 compound treatment 0.277 -0.00687 -0.95 0.283 -0.00607 -0.88 -1.2904 -0.9992 1334512 TimTec1_005113 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C34CC5CC4CCC(C5)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I10 compound treatment 0.414 0.13 17.98 0.415 0.126 18.19 25.575 1.0 1920628 TimTec1_005114 CN1/C(=C/C(=O)c2ccco2)/Sc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I11 compound treatment 0.276 -0.00787 -1.09 0.279 -0.0101 -1.45 -1.7967 -0.9897 3086180 TimTec1_005115 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NCc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I12 compound treatment 0.284 1.33E-4 0.02 0.288 -0.00107 -0.15 -0.0959 -0.6182 3212145 TimTec1_005116 CCOc1ccc(cc1)c2n[nH]c(=S)[nH]2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I13 compound treatment 0.308 0.0241 3.33 0.307 0.0179 2.59 4.1892 0.9922 3086182 TimTec1_005117 O=C(Nn1cnnc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I14 compound treatment 0.307 0.0231 3.2 0.301 0.0119 1.72 3.4787 0.958 3212146 TimTec1_005118 CCOc1ccc(/C=C/C(=O)Sc2ccc(Cl)cc2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I15 compound treatment 0.271 -0.0129 -1.78 0.273 -0.0161 -2.32 -2.8979 -0.9913 1487889 TimTec1_005119 OC(CNCN1C(=O)c2ccccc2C1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I16 compound treatment 0.277 -0.00687 -0.95 0.282 -0.00707 -1.02 -1.3926 -0.9993 3212147 TimTec1_005120 Cc1cc(C)c(C#N)c(SCC=C)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I17 compound treatment 0.299 0.0151 2.09 0.296 0.00693 1.0 2.1865 0.9432 1921119 TimTec1_005121 CCNc1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I18 compound treatment 0.278 -0.00587 -0.81 0.285 -0.00407 -0.59 -0.9885 -0.9875 3086186 TimTec1_005122 CS/C(=N\C#N)/NC1CCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I19 compound treatment 0.342 0.0581 8.03 0.333 0.0439 6.35 10.1662 0.9932 3212148 TimTec1_005123 O=C/1N(C2CCS(=O)(=O)C2)C(=S)S\C1=C/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I20 compound treatment 0.35 0.0661 9.14 0.347 0.0579 8.37 12.3776 0.999 1623935 TimTec1_005124 CCN(CC)c1ccc(N=C2C(=C(C#N)C#N)c3ccccc3C2=C(C#N)C#N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I21 compound treatment 0.339 0.0551 7.62 0.351 0.0619 8.95 11.7116 0.9968 3086189 TimTec1_005125 COCCN1C(=O)/C(=C\c2ccc3OCOc3c2)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I22 compound treatment 0.446 0.162 22.4 0.445 0.156 22.52 31.7652 1.0 3212149 TimTec1_005126 COc1cc2CC[C@H](NC(=O)C(F)(F)F)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I23 mock treatment 0.285 0.00113 0.16 0.291 0.00193 0.28 0.3082 0.9626 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 I24 positive control 0.283 -8.67E-4 -0.12 0.294 0.00493 0.71 0.4192 0.5802 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J01 compound treatment 0.291 0.00713 0.99 0.29 9.33E-4 0.13 0.7922 0.7964 3086191 TimTec1_005127 CC(C)C1CCC(C)CC1OC(=O)CN2CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J02 compound treatment 0.289 0.00513 0.71 0.284 -0.00507 -0.73 -0.016 -0.0157 1218294 TimTec1_005128 CC(C)(C)C(=O)NC(=S)Nc1cccc(O)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J03 compound treatment 0.293 0.00913 1.26 0.305 0.0159 2.3 2.5196 0.96 1240106 TimTec1_005129 C(Nc1ncnc2sc3CCCCc3c12)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J04 compound treatment 0.282 -0.00187 -0.26 0.283 -0.00607 -0.88 -0.802 -0.878 1554580 TimTec1_005130 Ic1ccccc1NC(=O)C2CN(C(=O)C2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J05 compound treatment 0.285 0.00113 0.16 0.289 -6.67E-5 -0.01 0.1039 0.6624 3212150 TimTec1_005131 OC(=O)C(Cc1c[nH]cn1)/N=C/c2cccc(CC=C)c2O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J06 compound treatment 0.375 0.0911 12.59 0.396 0.107 15.45 19.8246 0.9949 1532567 TimTec1_005132 CCCOc1ccccc1C2NC(=S)NC(=C2C(=O)OC3CCCC(C)C3)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J07 compound treatment 0.289 0.00513 0.71 0.294 0.00493 0.71 1.0053 1.0 3086259 TimTec1_005133 O=S(=O)(C1CCS(=O)(=O)C1)C2CCS(=O)(=O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J08 compound treatment 0.366 0.0821 11.35 0.364 0.0749 10.82 15.677 0.9997 1186821 TimTec1_005134 Cc1cc(C)c(NC(=O)C2CC3C4C=CC=CC4C2c5ccccc35)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J09 compound treatment 0.278 -0.00587 -0.81 0.284 -0.00507 -0.73 -1.0906 -0.9987 3212151 TimTec1_005135 COc1ccccc1C2C(C)C(C)(O)Oc3cc4OCOc4cc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J10 compound treatment 0.381 0.0971 13.42 0.384 0.0949 13.71 19.1851 0.9999 1139775 TimTec1_005136 Cc1cc(C(=O)O)c(CSc2ncn[nH]2)o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J11 compound treatment 0.281 -0.00287 -0.4 0.283 -0.00607 -0.88 -0.8997 -0.9356 1141408 TimTec1_005137 Cc1ccccc1Cn2cnc3ccccc3c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J12 compound treatment 0.284 1.33E-4 0.02 0.284 -0.00507 -0.73 -0.5045 -0.6891 1449011 TimTec1_005138 Cc1ccc(N2C(=O)CC(=O)N(C2=O)c3ccc(C)cc3C)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J13 compound treatment 0.331 0.0471 6.51 0.328 0.0389 5.62 8.5809 0.9973 1586155 TimTec1_005139 CC1=C(C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccccn3)C(=O)Nc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J14 compound treatment 0.306 0.0221 3.06 0.308 0.0189 2.73 4.096 0.9984 3086263 TimTec1_005140 CC(C)c1ccc(OCC(=O)Nc2ccccc2C(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J15 compound treatment 0.299 0.0151 2.09 0.309 0.0199 2.88 3.5143 0.9876 1332067 TimTec1_005141 CCOC(=O)c1c(C)oc(NC(=O)Nc2ccc(F)cc2)c1C(=O)OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J16 compound treatment 0.307 0.0231 3.2 0.317 0.0279 4.03 5.1129 0.9933 1544744 TimTec1_005142 Cc1c(OCc2ccc(F)cc2)ccc3c4CCCCc4c(=O)oc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J17 compound treatment 0.282 -0.00187 -0.26 0.286 -0.00307 -0.44 -0.4956 -0.9669 1496408 TimTec1_005143 CCc1nnc(NC(=O)CC(=O)Nc2ccccc2C(=O)O)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J18 compound treatment 0.281 -0.00287 -0.4 0.286 -0.00307 -0.44 -0.5933 -0.9984 1851913 TimTec1_005144 CC(C)CC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J19 compound treatment 0.599 0.315 43.54 0.601 0.312 45.06 62.645 0.9999 1716165 TimTec1_005145 NC(=O)c1sc(=S)n(c1N)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J20 compound treatment 0.363 0.0791 10.93 0.347 0.0579 8.37 13.6476 0.9913 3086267 TimTec1_005146 CC1SC(=NNC1=O)/N=C/c2ccc(F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J21 compound treatment 0.283 -8.67E-4 -0.12 0.285 -0.00407 -0.59 -0.5 -0.8341 3212152 TimTec1_005147 OC(=O)C(CC(=O)c1ccc(Cl)cc1)N(Cc2ccccc2)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J22 compound treatment 0.28 -0.00387 -0.53 0.287 -0.00207 -0.3 -0.5888 -0.9622 3086269 TimTec1_005148 C=CCN1C(SC=C1c2ccccc2)/N=C/c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J23 mock treatment 0.286 0.00213 0.29 0.291 0.00193 0.28 0.4059 0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 J24 positive control 0.288 0.00413 0.57 0.293 0.00393 0.57 0.8055 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K01 compound treatment 0.328 0.0441 6.1 0.33 0.0409 5.91 8.4921 0.9999 1023027 TimTec1_005149 Oc1ccccc1C(=O)CC(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K02 compound treatment 0.283 -8.67E-4 -0.12 0.289 -6.67E-5 -0.01 -0.0915 -0.7615 3212153 TimTec1_005150 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K03 compound treatment 0.281 -0.00287 -0.4 0.286 -0.00307 -0.44 -0.5933 -0.9984 3086271 TimTec1_005151 CC(C)NC(=O)C[n+]1csc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K04 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 1118603 TimTec1_005152 CN1CCN(Cc2cc(Br)cs2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K05 compound treatment 0.312 0.0281 3.89 0.316 0.0269 3.89 5.4992 1.0 3212154 TimTec1_005153 CC(O)c1cc(NC(=O)c2ccccc2)c(=O)oc1/C=C/N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K06 compound treatment 0.283 -8.67E-4 -0.12 0.288 -0.00107 -0.15 -0.1936 -0.9922 3086274 TimTec1_005154 CN(Cc1ccccc1)Cc2cccnc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K07 compound treatment 0.288 0.00413 0.57 0.281 -0.00807 -1.17 -0.4201 -0.3238 3212155 TimTec1_005155 O=C(/C=C/c1cccc(Oc2ccccc2)c1)N3CCOCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K08 compound treatment 0.285 0.00113 0.16 0.286 -0.00307 -0.44 -0.2025 -0.431 1586101 TimTec1_005156 CN(C)CCN(Cc1ccccc1)Cc2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K09 compound treatment 0.279 -0.00487 -0.67 0.279 -0.0101 -1.45 -1.5036 -0.9386 1051443 TimTec1_005157 FC(F)(F)CN1C(=O)c2ccccc2C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K10 compound treatment 0.281 -0.00287 -0.4 0.281 -0.00807 -1.17 -1.104 -0.897 1698764 TimTec1_005158 COc1ccc(NCc2cn3ccccc3n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K11 compound treatment 0.287 0.00313 0.43 0.285 -0.00407 -0.59 -0.1093 -0.1498 3212156 TimTec1_005159 N#CCCN1CCCC2(CCCC2)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K12 compound treatment 0.443 0.159 21.98 0.45 0.161 23.25 31.9828 0.9996 3212157 TimTec1_005160 O=C/1N=C(S\C1=C/c2cccs2)N3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K13 compound treatment 0.295 0.0111 1.54 0.284 -0.00507 -0.73 0.5701 0.3347 1604720 TimTec1_005161 CCc1c(C)nc2ccccc2c1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K14 compound treatment 0.289 0.00513 0.71 0.279 -0.0101 -1.45 -0.5267 -0.3256 3212158 TimTec1_005162 Cc1cc(C)cc(Nc2csc(N/C=N\O)n2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K15 compound treatment 0.284 1.33E-4 0.02 0.289 -6.67E-5 -0.01 0.0062 0.299 3086348 TimTec1_005163 OC(=O)c1ccccc1NCn2nnc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K16 compound treatment 0.288 0.00413 0.57 0.289 -6.67E-5 -0.01 0.397 0.6951 3212159 TimTec1_005164 Clc1ccc(cc1)C2=CC=C(C#N)C(N2)SCc3nc4ccccc4[nH]3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K17 compound treatment 0.34 0.0561 7.75 0.326 0.0369 5.33 9.2558 0.9833 1472272 TimTec1_005165 CNc1nc(nc(n1)N2CCOCC2)N(c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K18 compound treatment 0.345 0.0611 8.45 0.351 0.0619 8.95 12.2977 0.9996 3086351 TimTec1_005166 CCCC1CCC(CC1)c2ccc(cc2)/C(=N/O)/N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K19 compound treatment 0.343 0.0591 8.17 0.347 0.0579 8.37 11.6938 0.9999 3212160 TimTec1_005167 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K20 compound treatment 0.289 0.00513 0.71 0.286 -0.00307 -0.44 0.1882 0.2251 1130551 TimTec1_005168 COc1ccc(cc1)N(C(=O)c2ccco2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K21 compound treatment 0.319 0.0351 4.85 0.317 0.0279 4.03 6.2852 0.9958 3212161 TimTec1_005169 FC(F)(F)c1ccccc1NC(NC(=O)c2ccco2)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K22 compound treatment 0.289 0.00513 0.71 0.295 0.00593 0.86 1.1075 0.9956 1915266 TimTec1_005170 Cc1cc[n+](CCC(=O)O)c2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K23 mock treatment 0.286 0.00213 0.29 0.291 0.00193 0.28 0.4059 0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 K24 positive control 0.288 0.00413 0.57 0.29 9.33E-4 0.13 0.4991 0.8507 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L01 compound treatment 0.293 0.00913 1.26 0.286 -0.00307 -0.44 0.579 0.433 1383984 TimTec1_005171 CCC1=CC(C)(CC)Nc2cc(C)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L02 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 1409216 TimTec1_005172 COc1cc(cc(OC)c1OC)C(=O)N(C)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L03 compound treatment 0.282 -0.00187 -0.26 0.288 -0.00107 -0.15 -0.2913 -0.9697 1273531 TimTec1_005173 OCC(O)C1OC(OCC1O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L04 compound treatment 0.32 0.0361 4.99 0.322 0.0329 4.76 6.8935 0.9997 1385587 TimTec1_005174 Cc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3c(C)cccc3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L05 compound treatment 0.357 0.0731 10.1 0.368 0.0789 11.4 15.2063 0.9982 3212235 TimTec1_005175 OC(=O)C(Cc1ccc(O)cc1)/N=C/c2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L06 compound treatment 0.349 0.0651 9.0 0.343 0.0539 7.79 11.8714 0.9974 3086357 TimTec1_005176 COC(=O)c1c(NC(=O)C(F)(F)F)sc2CCCCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L07 compound treatment 0.284 1.33E-4 0.02 0.287 -0.00207 -0.3 -0.1981 -0.6622 1333937 TimTec1_005177 O=S(=O)(C1CCS(=O)(=O)C1)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L08 compound treatment 0.28 -0.00387 -0.53 0.286 -0.00307 -0.44 -0.691 -0.9957 1533793 TimTec1_005178 Cc1ccc(NC(=O)C2C(C=CC(C2C(=O)O)c3ccccc3)c4ccccc4)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L09 compound treatment 0.276 -0.00787 -1.09 0.281 -0.00807 -1.17 -1.5924 -0.9994 1611679 TimTec1_005179 COc1ccc(cc1)C(C2=C(O)CCCC2=O)c3cc4OCOc4cc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L10 compound treatment 0.29 0.00613 0.85 0.287 -0.00207 -0.3 0.3881 0.432 1081231 TimTec1_005180 O=C1N(C(=O)c2nccnc12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L11 compound treatment 0.327 0.0431 5.96 0.328 0.0389 5.62 8.1902 0.9996 1700569 TimTec1_005181 CCOC(=O)C1=C(O)c2ccccc2NC(=O)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L12 compound treatment 0.303 0.0191 2.64 0.304 0.0149 2.16 3.3944 0.9949 1371927 TimTec1_005182 Cc1cccc2c(cc(nc12)c3ccccc3)C(=O)NC(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L13 compound treatment 0.312 0.0281 3.89 0.317 0.0279 4.03 5.6013 0.9998 3086362 TimTec1_005183 Cc1cc2ncc(nc2cc1C)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L14 compound treatment 0.334 0.0501 6.93 0.329 0.0399 5.77 8.9761 0.9959 1442595 TimTec1_005184 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(I)cc3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L15 compound treatment 0.359 0.0751 10.38 0.366 0.0769 11.11 15.1974 0.9994 3086440 TimTec1_005185 CCOC(=O)/C(=C(/N)\c1cc2cccc(OC)c2oc1=O)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L16 compound treatment 0.406 0.122 16.87 0.379 0.0899 12.99 21.1166 0.9917 1612648 TimTec1_005186 CC1CCN(Cc2cc3c(cc(=O)oc3c(C)c2O)c4ccccc4)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L17 compound treatment 0.282 -0.00187 -0.26 0.282 -0.00707 -1.02 -0.9041 -0.8588 3212236 TimTec1_005187 Cn1cnnc1SCc2cccc(CSc3nncn3C)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L18 compound treatment 0.293 0.00913 1.26 0.289 -6.67E-5 -0.01 0.8854 0.7017 3086444 TimTec1_005188 CCN(CC)c1ccc(/N=C/c2ccc3ccccc3n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L19 compound treatment 0.28 -0.00387 -0.53 0.281 -0.00807 -1.17 -1.2016 -0.9375 1589064 TimTec1_005189 Clc1c(sc2ccccc12)C(=O)N3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L20 compound treatment 0.377 0.0931 12.87 0.372 0.0829 11.98 17.5687 0.9994 3212237 TimTec1_005190 CC1SC(=NNC1=O)/N=C/c2ccc(O)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L21 compound treatment 0.277 -0.00687 -0.95 0.278 -0.0111 -1.6 -1.8011 -0.969 3086447 TimTec1_005191 CC(NC(CC(=O)c1ccc(F)cc1)C(=O)O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L22 compound treatment 0.321 0.0371 5.13 0.322 0.0329 4.76 6.9912 0.9993 1451936 TimTec1_005192 CCCc1cc(=O)oc2cc(OCc3ccccc3)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L23 mock treatment 0.287 0.00313 0.43 0.29 9.33E-4 0.13 0.4014 0.8854 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 L24 positive control 0.285 0.00113 0.16 0.289 -6.67E-5 -0.01 0.1039 0.6624 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M01 compound treatment 0.29 0.00613 0.85 0.292 0.00293 0.42 0.8988 0.9487 3086449 TimTec1_005193 CCOC(=O)CN1CCN(CC1)C=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M02 compound treatment 0.306 0.0221 3.06 0.308 0.0189 2.73 4.096 0.9984 3212238 TimTec1_005194 O=C(/C=C\Nc1cccc(N/C=C\C(=O)c2ccccc2)c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M03 compound treatment 0.29 0.00613 0.85 0.293 0.00393 0.57 1.0009 0.9811 1445055 TimTec1_005195 Cc1ccccc1OC(=O)Cn2c(=O)sc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M04 compound treatment 0.287 0.00313 0.43 0.29 9.33E-4 0.13 0.4014 0.8854 1718720 TimTec1_005196 CN1CCN(Cc2coc3ccccc3c2=O)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M05 compound treatment 0.288 0.00413 0.57 0.289 -6.67E-5 -0.01 0.397 0.6951 1415720 TimTec1_005197 OCC1Sc2ccccc2NC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M06 compound treatment 0.285 0.00113 0.16 0.291 0.00193 0.28 0.3082 0.9626 1643885 TimTec1_005198 NC(=O)C1CCN(Cc2ccc(Cl)cc2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M07 compound treatment 0.329 0.0451 6.24 0.325 0.0359 5.19 8.0791 0.9958 3212239 TimTec1_005199 COc1ccc2c3CC[C@](C)(CCC(=O)O)C(=O)c3ccc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M08 compound treatment 0.339 0.0551 7.62 0.343 0.0539 7.79 10.8945 0.9999 3086453 TimTec1_005200 Cc1ccc(C(=O)Sc2nc(N)c(C#N)cc2C#N)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M09 compound treatment 0.331 0.0471 6.51 0.326 0.0369 5.33 8.3767 0.9951 1212803 TimTec1_005201 CCOc1ccc2c(cc(=O)oc2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M10 compound treatment 0.288 0.00413 0.57 0.294 0.00493 0.71 0.9077 0.994 3086455 TimTec1_005202 COc1ccc(cc1)c2cc(nc(=O)[nH]2)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M11 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 1222652 TimTec1_005203 CCc1cc2OCCOc2cc1C(=O)c3ccc(I)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M12 compound treatment 0.276 -0.00787 -1.09 0.283 -0.00607 -0.88 -1.3881 -0.9943 1107292 TimTec1_005204 CCC1SC2=NCCN2C1(O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M13 compound treatment 0.283 -8.67E-4 -0.12 0.281 -0.00807 -1.17 -0.9086 -0.7757 1431781 TimTec1_005205 CC1(C)CC2(CCCN(CCC(O)(c3ccccc3)c4ccccc4)C2)CCO1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M14 compound treatment 0.319 0.0351 4.85 0.316 0.0269 3.89 6.183 0.994 1622469 TimTec1_005206 CCCCn1c(nn(c1=O)S(=O)(=O)c2ccc(Br)cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M15 compound treatment 0.302 0.0181 2.51 0.309 0.0199 2.88 3.8074 0.9976 1265308 TimTec1_005207 OC(=O)c1ccccc1C(=O)Nc2cccc3ncccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M16 compound treatment 0.29 0.00613 0.85 0.286 -0.00307 -0.44 0.2859 0.299 3086459 TimTec1_005208 CSC1=Nc2ccccc2CN1c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M17 compound treatment 0.306 0.0221 3.06 0.303 0.0139 2.01 3.5853 0.9794 3086461 TimTec1_005209 O=C(Nc1nc[nH]n1)Nc2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M18 compound treatment 0.282 -0.00187 -0.26 0.28 -0.00907 -1.31 -1.1084 -0.8304 1609905 TimTec1_005210 CCCC1CCC(CC1)c2ccc(cc2)C(=O)CCN(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M19 compound treatment 0.332 0.0481 6.65 0.333 0.0439 6.35 9.1893 0.9997 3212240 TimTec1_005211 Cc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M20 compound treatment 0.285 0.00113 0.16 0.281 -0.00807 -1.17 -0.7132 -0.6066 3085449 TimTec1_005212 CC[C@@]1(C)N[C@@H](CS1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M21 compound treatment 0.333 0.0491 6.79 0.332 0.0429 6.2 9.1849 0.999 1601693 TimTec1_005213 O=C(NC(Nc1cccc2ccccc12)C(=O)c3ccccc3)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M22 compound treatment 0.282 -0.00187 -0.26 0.285 -0.00407 -0.59 -0.5977 -0.9317 1269343 TimTec1_005214 CC(CC(=O)c1ccccc1)CC(=O)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M23 mock treatment 0.285 0.00113 0.16 0.292 0.00293 0.42 0.4103 0.9084 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 M24 positive control 0.286 0.00213 0.29 0.284 -0.00507 -0.73 -0.3091 -0.3918 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N01 compound treatment 0.292 0.00813 1.12 0.286 -0.00307 -0.44 0.4813 0.3985 3085453 TimTec1_005215 Cc1cc(C)c(CC2C(=O)c3ccccc3C2=O)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N02 compound treatment 0.276 -0.00787 -1.09 0.279 -0.0101 -1.45 -1.7967 -0.9897 1524336 TimTec1_005216 O=C(NCCc1nc2ccccc2[nH]1)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N03 compound treatment 0.297 0.0131 1.81 0.3 0.0109 1.58 2.3997 0.9976 1139245 TimTec1_005217 O=C(Cc1ccccc1)c2ccc3OCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N04 compound treatment 0.283 -8.67E-4 -0.12 0.283 -0.00607 -0.88 -0.7043 -0.7963 1718136 TimTec1_005218 O=c1oc2ccccc2cc1c3nnc(o3)c4cccc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N05 compound treatment 0.482 0.198 27.37 0.484 0.195 28.16 39.2654 0.9999 3085456 TimTec1_005219 CC1(C)CC(=O)C2C(=Nc3ccccc3N=C2c4ccccc4)C1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N06 compound treatment 0.287 0.00313 0.43 0.285 -0.00407 -0.59 -0.1093 -0.1498 1256766 TimTec1_005220 CC1N(c2cccc(C)c2)C3(CCCCC3)SC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N07 compound treatment 0.283 -8.67E-4 -0.12 0.286 -0.00307 -0.44 -0.3979 -0.8671 1496277 TimTec1_005221 NC(=O)C(C1CCS(=O)(=O)C1)C(=O)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N08 compound treatment 0.282 -0.00187 -0.26 0.278 -0.0111 -1.6 -1.3127 -0.8107 1400156 TimTec1_005222 NNC(=O)C1CCCN1S(=O)(=O)c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N09 compound treatment 0.294 0.0101 1.4 0.294 0.00493 0.71 1.4938 0.9509 1525056 TimTec1_005223 COc1ccc(cc1)C2C3C(=O)CCCC3(O)Oc4cc5OCOc5cc24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N10 compound treatment 0.295 0.0111 1.54 0.3 0.0109 1.58 2.2043 0.9999 1231285 TimTec1_005224 CCN(CC)c1ccc2cc(c3ncc(o3)c4ccc(F)cc4)c(=O)oc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N11 compound treatment 0.273 -0.0109 -1.5 0.28 -0.00907 -1.31 -1.9876 -0.9977 3212241 TimTec1_005225 COc1cc2CCN(C)[C@H](Cc3ccc(O)cc3)c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N12 compound treatment 0.326 0.0421 5.82 0.306 0.0169 2.45 5.8455 0.9258 1135918 TimTec1_005226 Oc1ccccc1C2=Nc3ncnn3C(C2)c4ccc(Cl)cc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N13 compound treatment 0.477 0.193 26.68 0.48 0.191 27.58 38.3684 0.9999 3212242 TimTec1_005227 CCC[n+]1ccc(cc1)c2c[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N14 compound treatment 0.31 0.0261 3.61 0.306 0.0169 2.45 4.2824 0.982 1154608 TimTec1_005228 CC(C)c1ccc(OC(=O)C(C)N2C(=O)c3ccccc3C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N15 compound treatment 0.349 0.0651 9.0 0.337 0.0479 6.92 11.2586 0.9916 3212243 TimTec1_005229 CCOC(=O)/C(=C(/N)\c1cc2cc(Br)cc(Br)c2oc1=O)/C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N16 compound treatment 0.303 0.0191 2.64 0.294 0.00493 0.71 2.373 0.8668 1059298 TimTec1_005230 Cc1cc2oc(=O)c3CCCCc3c2c(O)c1CN4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N17 compound treatment 0.279 -0.00487 -0.67 0.281 -0.00807 -1.17 -1.2993 -0.9659 1365174 TimTec1_005231 NC(=O)CNC(=O)c1cccc(Cl)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N18 compound treatment 0.281 -0.00287 -0.4 0.281 -0.00807 -1.17 -1.104 -0.897 3085464 TimTec1_005232 CC(N1C(=O)CCC1=O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N19 compound treatment 0.319 0.0351 4.85 0.317 0.0279 4.03 6.2852 0.9958 3212244 TimTec1_005233 COC(=O)c1cc(Br)ccc1OC(=O)/C=C/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N20 compound treatment 0.321 0.0371 5.13 0.314 0.0249 3.6 6.1741 0.985 3085466 TimTec1_005234 Oc1ccccc1/C=N/C2=NNC(=O)CS2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N21 compound treatment 0.297 0.0131 1.81 0.303 0.0139 2.01 2.7061 0.9987 3212245 TimTec1_005235 Cc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N22 compound treatment 0.337 0.0531 7.34 0.343 0.0539 7.79 10.6991 0.9996 1411087 TimTec1_005236 CCOC(=O)Cc1cc(=O)oc2cc(OCC)ccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N23 mock treatment 0.283 -8.67E-4 -0.12 0.29 9.33E-4 0.13 0.0107 0.0592 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 N24 positive control 0.285 0.00113 0.16 0.288 -0.00107 -0.15 0.0018 0.008 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O01 compound treatment 0.289 0.00513 0.71 0.28 -0.00907 -1.31 -0.4246 -0.2851 3212318 TimTec1_005237 C=CCOC(=O)OCn1c(=O)sc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O02 compound treatment 0.281 -0.00287 -0.4 0.29 9.33E-4 0.13 -0.1847 -0.4415 3212319 TimTec1_005238 CCCCN1N=C(C)CC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O03 compound treatment 0.347 0.0631 8.72 0.351 0.0619 8.95 12.4931 0.9999 3212320 TimTec1_005239 O=C(Cn1c(=O)sc2ccccc12)OC(C(=O)c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O04 compound treatment 0.283 -8.67E-4 -0.12 0.286 -0.00307 -0.44 -0.3979 -0.8671 1379879 TimTec1_005240 CN1CCN(Cc2ccc(NC(=O)C)cc2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O05 compound treatment 0.285 0.00113 0.16 0.287 -0.00207 -0.3 -0.1004 -0.2978 1721138 TimTec1_005241 CC1CN(CC2COC(C)(C)O2)CC(C)O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O06 compound treatment 0.284 1.33E-4 0.02 0.287 -0.00207 -0.3 -0.1981 -0.6622 1672440 TimTec1_005242 NC(=O)C1CCN(CC2CCC=CC2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O07 compound treatment 0.287 0.00313 0.43 0.292 0.00293 0.42 0.6057 0.9999 1624424 TimTec1_005243 COc1cc2c3CCc4cn[nH]c4-c3ccc2c(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O08 compound treatment 0.281 -0.00287 -0.4 0.288 -0.00107 -0.15 -0.389 -0.9154 1736587 TimTec1_005244 Fc1ccc(cc1)C(=O)Oc2ccccc2c3cnc4ccccc4n3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O09 compound treatment 0.34 0.0561 7.75 0.351 0.0619 8.95 11.8093 0.9975 1502476 TimTec1_005245 CC(C)C(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)coc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O10 compound treatment 0.275 -0.00887 -1.22 0.281 -0.00807 -1.17 -1.6901 -0.9997 1214549 TimTec1_005246 COc1cc(ccc1O)C2CS(=O)(=O)CS(=O)(=O)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O11 compound treatment 0.275 -0.00887 -1.22 0.279 -0.0101 -1.45 -1.8944 -0.9964 1679192 TimTec1_005247 O=C(c1cccs1)c2ccc3OCCCOc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O12 compound treatment 0.276 -0.00787 -1.09 0.282 -0.00707 -1.02 -1.4903 -0.9995 3086118 TimTec1_005248 FC(F)(F)c1ccc2c(Cl)ccnc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O13 compound treatment 0.285 0.00113 0.16 0.279 -0.0101 -1.45 -0.9175 -0.6273 1449875 TimTec1_005249 CN(C)CCC(=O)c1ccc2OCCCOc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O14 compound treatment 0.317 0.0331 4.58 0.315 0.0259 3.75 5.8855 0.995 3086120 TimTec1_005250 S=c1[nH]c(ccc1C#N)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O15 compound treatment 0.278 -0.00587 -0.81 0.284 -0.00507 -0.73 -1.0906 -0.9987 1687305 TimTec1_005251 O=C1N(C(=O)c2ccccc12)c3ccc4ncccc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O16 compound treatment 0.284 1.33E-4 0.02 0.276 -0.0131 -1.89 -1.3216 -0.7002 1675695 TimTec1_005252 CN1C2OC(=C(C#N)C(C2C(=O)N(C)C1=O)c3cccc(Br)c3)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O17 compound treatment 0.284 1.33E-4 0.02 0.289 -6.67E-5 -0.01 0.0062 0.299 3086122 TimTec1_005253 O=C(/C=C/c1ccccc1)N2C(COC2=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O18 compound treatment 0.28 -0.00387 -0.53 0.281 -0.00807 -1.17 -1.2016 -0.9375 3212321 TimTec1_005254 CCN(CC)[P+](NC(=O)c1ccccc1)(N(CC)CC)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O19 compound treatment 0.376 0.0921 12.73 0.373 0.0839 12.12 17.5731 0.9997 3212322 TimTec1_005255 O=C(NC1CCCCC1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O20 compound treatment 0.317 0.0331 4.58 0.312 0.0229 3.31 5.5791 0.9874 3086125 TimTec1_005256 O[C@@H]1CO[C@@H](Nc2ccccc2)[C@H](O)[C@H]1O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O21 compound treatment 0.276 -0.00787 -1.09 0.281 -0.00807 -1.17 -1.5924 -0.9994 1457665 TimTec1_005257 OP(=O)(c1nc2ccccc2n1CC=C)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O22 compound treatment 0.275 -0.00887 -1.22 0.279 -0.0101 -1.45 -1.8944 -0.9964 1597857 TimTec1_005258 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O23 mock treatment 0.283 -8.67E-4 -0.12 0.291 0.00193 0.28 0.1128 0.3713 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 O24 positive control 0.277 -0.00687 -0.95 0.284 -0.00507 -0.73 -1.1883 -0.9918 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P01 compound treatment 0.289 0.00513 0.71 0.284 -0.00507 -0.73 -0.016 -0.0157 3212323 TimTec1_005259 C[n+]1cn(NC(=O)c2ccc(cc2)C(=O)ON3C(=O)CCC3=O)cn1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P02 compound treatment 0.293 0.00913 1.26 0.29 9.33E-4 0.13 0.9875 0.7782 3212324 TimTec1_005260 OC(=O)C(Cc1ccccc1)NCc2c(O)ccc3c4CCCCc4c(=O)oc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P03 compound treatment 0.292 0.00813 1.12 0.297 0.00793 1.15 1.6048 1.0 1665007 TimTec1_005261 COc1ccc(CCC(=O)c2ccc3OCCOc3c2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P04 compound treatment 0.286 0.00213 0.29 0.29 9.33E-4 0.13 0.3037 0.9372 3212325 TimTec1_005262 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NN4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P05 compound treatment 0.302 0.0181 2.51 0.309 0.0199 2.88 3.8074 0.9976 3086129 TimTec1_005263 Oc1ccc(Cl)cc1/C=N/CCc2c[nH]c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P06 compound treatment 0.288 0.00413 0.57 0.289 -6.67E-5 -0.01 0.397 0.6951 1176935 TimTec1_005264 CC(=O)Nc1cccc(NC(=O)N2CCOCC2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P07 compound treatment 0.286 0.00213 0.29 0.289 -6.67E-5 -0.01 0.2016 0.6836 3086130 TimTec1_005265 CN(N)P(=O)(c1ccccc1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P08 compound treatment 0.283 -8.67E-4 -0.12 0.288 -0.00107 -0.15 -0.1936 -0.9922 3212326 TimTec1_005266 OC(=O)c1ccccc1C(=O)Nc2ccc(/C=C/c3ccccc3)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P09 compound treatment 0.279 -0.00487 -0.67 0.29 9.33E-4 0.13 -0.3801 -0.5543 1689960 TimTec1_005267 COc1ccc(cc1)C2C(C)C(C)(Oc3cc4OCOc4cc23)N5CCCC5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P10 compound treatment 0.37 0.0861 11.9 0.372 0.0829 11.98 16.8848 1.0 3212327 TimTec1_005268 CC(C)c1ccc(cc1)C2C(=C(N)SC(=C2C#N)N)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P11 compound treatment 0.292 0.00813 1.12 0.293 0.00393 0.57 1.1963 0.9501 1088185 TimTec1_005269 COc1cc2C=CN(C(C#N)c2cc1OC)C(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P12 compound treatment 0.301 0.0171 2.37 0.298 0.00893 1.29 2.5862 0.9593 1306739 TimTec1_005270 CC(C)CNc1ncnc2sc3CCCCc3c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P13 compound treatment 0.289 0.00513 0.71 0.299 0.00993 1.43 1.516 0.9472 1251200 TimTec1_005271 O=C1CC(N2CCCc3ccccc23)C(=O)N1c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P14 compound treatment 0.331 0.0471 6.51 0.336 0.0469 6.78 9.398 0.9998 1588848 TimTec1_005272 Cc1ccc(CNc2nc3n(C)c(=O)[nH]c(=O)c3n2Cc4ccccc4C)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P15 compound treatment 0.317 0.0331 4.58 0.317 0.0279 4.03 6.0898 0.998 1071878 TimTec1_005273 COc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P16 compound treatment 0.383 0.0991 13.7 0.368 0.0789 11.4 17.7462 0.9958 1718803 TimTec1_005274 Cc1cc(OC(=O)CNC(=O)OCc2ccccc2)cc3oc(=O)c4ccccc4c13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P17 compound treatment 0.277 -0.00687 -0.95 0.282 -0.00707 -1.02 -1.3926 -0.9993 1656249 TimTec1_005275 CCC(Cc1cccc(O)c1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P18 compound treatment 0.318 0.0341 4.72 0.317 0.0279 4.03 6.1875 0.997 1501431 TimTec1_005276 Brc1ccc(cc1)N2C(=O)CC(Nc3c[nH]c(=O)[nH]c3=O)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P19 compound treatment 0.287 0.00313 0.43 0.284 -0.00507 -0.73 -0.2114 -0.2486 3212328 TimTec1_005277 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NC3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P20 compound treatment 0.39 0.106 14.66 0.374 0.0849 12.27 19.0429 0.9961 3086198 TimTec1_005278 Oc1ccccc1/C=N/C2=NNC(=CS2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P21 compound treatment 0.279 -0.00487 -0.67 0.28 -0.00907 -1.31 -1.4015 -0.952 3086200 TimTec1_005279 N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P22 compound treatment 0.391 0.107 14.8 0.391 0.102 14.72 20.8769 1.0 1555180 TimTec1_005280 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2cc3oc(=O)c(Cl)c(C)c3cc2Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P23 mock treatment 0.285 0.00113 0.16 0.283 -0.00607 -0.88 -0.5089 -0.5717 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2077 P24 positive control 0.281 -0.00287 -0.4 0.292 0.00293 0.42 0.0196 0.0337 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A01 compound treatment 0.275 -0.0164 -2.27 0.27 -0.0199 -2.88 -3.638 -0.993 3211440 TimTec1_005633 CC(=O)n1cc(/C=c\2/sc3nc4c(C)c(C)ccc4n3c2=O)c(n1)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A02 compound treatment 0.348 0.0566 7.82 0.334 0.0441 6.37 10.03 0.9948 3085592 TimTec1_005634 Cc1nc(N)sc1c2csc(Nc3cccc(Cl)c3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A03 compound treatment 0.279 -0.0124 -1.71 0.274 -0.0159 -2.3 -2.8387 -0.9894 3211529 TimTec1_005635 CCC(=O)N1N=C(CC1(O)c2ccc(F)cc2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A04 compound treatment 0.274 -0.0174 -2.4 0.268 -0.0219 -3.17 -3.94 -0.9907 1419705 TimTec1_005636 CC1CCC(=C(C#N)C(=O)NCc2ccccc2)CC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A05 compound treatment 0.291 -4.0E-4 -0.06 0.292 0.00207 0.3 0.172 0.5666 1732858 TimTec1_005637 Fc1ccc2C(=O)N(C3CCCCCCC3)C(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A06 compound treatment 0.323 0.0316 4.37 0.312 0.0221 3.19 5.3408 0.9881 3211530 TimTec1_005638 Fc1ccc(cc1)C2Nc3ccc(OC(F)(F)F)cc3C4C=CCC42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A07 compound treatment 0.281 -0.0104 -1.44 0.278 -0.0119 -1.72 -2.2348 -0.9959 1737054 TimTec1_005639 Nn1c(CO)nc2ccccc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A08 compound treatment 0.276 -0.0154 -2.13 0.274 -0.0159 -2.3 -3.1318 -0.9992 1175030 TimTec1_005640 CC(C)(O)c1cn2ccccc2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A09 compound treatment 0.274 -0.0174 -2.4 0.269 -0.0209 -3.02 -3.8379 -0.9935 1364286 TimTec1_005641 COc1ccc(cc1)C(CC#N)C2CCOC(C)(C)C2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A10 compound treatment 0.271 -0.0204 -2.82 0.268 -0.0219 -3.17 -4.2331 -0.9983 1357576 TimTec1_005642 O=C(NCCc1ccc(cc1)S(=O)(=O)N2CCCC2)c3cccs3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A11 compound treatment 0.383 0.0916 12.65 0.354 0.0641 9.25 15.4919 0.9882 3211531 TimTec1_005643 CNC(=S)N(C)/N=C\1/C(=O)N(Cc2c(Cl)cccc2Cl)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A12 compound treatment 0.289 -0.0024 -0.33 0.282 -0.00793 -1.15 -1.0447 -0.8758 3085598 TimTec1_005644 CCc1nn2c(C)cc(O)nc2c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A13 compound treatment 0.277 -0.0144 -1.99 0.272 -0.0179 -2.59 -3.2384 -0.9915 1530862 TimTec1_005645 C1Cc2c(C1)c3c(ccc4ccccc43)nc2c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A14 compound treatment 0.31 0.0186 2.57 0.307 0.0171 2.47 3.5602 0.9998 1575017 TimTec1_005646 CC1CN(OC(O1)c2ccc3OCOc3c2)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A15 compound treatment 0.273 -0.0184 -2.54 0.27 -0.0199 -2.88 -3.8334 -0.9981 3085600 TimTec1_005647 OC(=O)C1CC(=O)N(Cc2ccccc2)/C(=N/c3ccc(F)cc3)/S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A16 compound treatment 0.269 -0.0224 -3.09 0.264 -0.0259 -3.75 -4.837 -0.9955 1628881 TimTec1_005648 CCC(N)C1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A17 compound treatment 0.275 -0.0164 -2.27 0.272 -0.0179 -2.59 -3.4338 -0.9978 3085602 TimTec1_005649 FC(F)(F)c1cccc(NCn2c(=S)oc3ccc(Cl)cc23)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A18 compound treatment 0.279 -0.0124 -1.71 0.275 -0.0149 -2.16 -2.7366 -0.9935 1127153 TimTec1_005650 CC(C)c1ccccc1NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A19 compound treatment 0.279 -0.0124 -1.71 0.275 -0.0149 -2.16 -2.7366 -0.9935 1348096 TimTec1_005651 CN(C)c1nc2n(C)c(=O)n(C)c(=O)c2n1CC(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A20 compound treatment 0.276 -0.0154 -2.13 0.271 -0.0189 -2.73 -3.4382 -0.9923 1611764 TimTec1_005652 COC(=O)CCn1cc(F)c(N)nc1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A21 compound treatment 0.335 0.0436 6.02 0.33 0.0401 5.79 8.3515 0.9998 1564099 TimTec1_005653 CN(C)N=Nc1ccc(cc1)S(=O)(=O)NC(=O)Cc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A22 compound treatment 0.273 -0.0184 -2.54 0.269 -0.0209 -3.02 -3.9355 -0.9963 1394944 TimTec1_005654 C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A23 mock treatment 0.278 -0.0134 -1.85 0.279 -0.0109 -1.58 -2.4257 -0.9969 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 A24 positive control 0.272 -0.0194 -2.68 0.268 -0.0219 -3.17 -4.1354 -0.9965 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B01 compound treatment 0.441 0.15 20.67 0.386 0.0961 13.88 24.4262 0.9812 3211532 TimTec1_005655 SC1=NC(=O)/C(=C\c2cccnc2)/S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B02 compound treatment 0.33 0.0386 5.33 0.323 0.0331 4.78 7.1481 0.9985 1491875 TimTec1_005656 COc1ccc(cc1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B03 compound treatment 0.291 -4.0E-4 -0.06 0.289 -9.33E-4 -0.13 -0.1344 -0.9225 3085609 TimTec1_005657 Cc1nn(c(O)c1CCC#N)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B04 compound treatment 0.313 0.0216 2.98 0.309 0.0191 2.75 4.0575 0.9992 3211533 TimTec1_005658 FC(F)(F)C(NCC1(CC2CC3CC(C2)C1)C3)(NC(=O)c4ccccc4)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B05 compound treatment 0.498 0.207 28.54 0.503 0.213 30.78 41.9446 0.9993 3085612 TimTec1_005659 COc1cc(NC=C2C(=O)NC(=O)NC2=O)cc(OC)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B06 compound treatment 0.287 -0.0044 -0.61 0.287 -0.00293 -0.42 -0.7294 -0.9844 3085613 TimTec1_005660 Cc1cc(cc(C)c1O)C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B07 compound treatment 0.416 0.125 17.21 0.407 0.117 16.91 24.1289 1.0 3211534 TimTec1_005661 FC(F)(F)c1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B08 compound treatment 0.368 0.0766 10.58 0.363 0.0731 10.55 14.9458 1.0 1339353 TimTec1_005662 CCc1ccc(cc1)C(=O)c2c(c(c3cc(ccn23)C(C)(C)C)S(=O)(=O)CC)S(=O)(=O)CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B09 compound treatment 0.29 -0.0014 -0.19 0.288 -0.00193 -0.28 -0.3342 -0.9839 1735427 TimTec1_005663 CC1(C)CC(=O)CC(C)(C)N1OC(=O)c2ccccn2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B10 compound treatment 0.297 0.0056 0.77 0.295 0.00507 0.73 1.0646 0.9996 1503527 TimTec1_005664 CCC(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B11 compound treatment 0.287 -0.0044 -0.61 0.286 -0.00393 -0.57 -0.8316 -0.9994 1555325 TimTec1_005665 CCOc1ccccc1NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B12 compound treatment 0.357 0.0656 9.06 0.355 0.0651 9.4 13.0541 0.9998 3085617 TimTec1_005666 COc1ccc(/C=N/n2c(=O)c(nn3cnnc23)C(C)(C)C)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B13 compound treatment 0.291 -4.0E-4 -0.06 0.292 0.00207 0.3 0.172 0.5666 1402991 TimTec1_005667 Cc1ccc(Oc2cc(C#N)c(C#N)cc2n3nnc4ccccc34)cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B14 compound treatment 0.346 0.0546 7.54 0.346 0.0561 8.1 11.0603 0.9994 3085619 TimTec1_005668 CC/N=C\1/S/C(=C/c2sccc2C)/C(=O)N1CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B15 compound treatment 0.233 -0.0584 -8.07 0.235 -0.0549 -7.93 -11.3158 -1.0 1257857 TimTec1_005669 OC1=C(C(C#Cc2ccccc2)C3=C(O)CCCC3=O)C(=O)CCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B16 compound treatment 0.304 0.0126 1.74 0.301 0.0111 1.6 2.3612 0.9991 1631021 TimTec1_005670 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3c(C)ccc4nsnc34 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B17 compound treatment 0.292 6.0E-4 0.08 0.292 0.00207 0.3 0.2697 0.8705 1219783 TimTec1_005671 COc1ccc(cc1)N2C(=O)NC(=O)C(Cc3ccc(O)c(OC)c3)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B18 compound treatment 0.287 -0.0044 -0.61 0.287 -0.00293 -0.42 -0.7294 -0.9844 3211535 TimTec1_005672 Cc1cc(NC(=O)NC(=O)c2ccc(F)cc2)n[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B19 compound treatment 0.284 -0.0074 -1.02 0.282 -0.00793 -1.15 -1.5332 -0.9984 1033315 TimTec1_005673 Cc1cc(C)n(n1)C(=S)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B20 compound treatment 0.297 0.0056 0.77 0.295 0.00507 0.73 1.0646 0.9996 3085624 TimTec1_005674 CSc1snc(O)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B21 compound treatment 0.291 -4.0E-4 -0.06 0.29 6.67E-5 0.01 -0.0323 -0.5752 3211536 TimTec1_005675 CCc1ccc(cc1)C2=Nn3c(C)nnc3SC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B22 compound treatment 0.351 0.0596 8.23 0.324 0.0341 4.92 9.3017 0.9697 3085626 TimTec1_005676 O=C(Nc1cccc(c1)c2nnc(o2)c3ccco3)C(c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B23 mock treatment 0.293 0.0016 0.22 0.293 0.00307 0.44 0.4695 0.9484 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 B24 positive control 0.288 -0.0034 -0.47 0.288 -0.00193 -0.28 -0.5296 -0.9692 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C01 compound treatment 0.301 0.0096 1.33 0.309 0.0191 2.75 2.8852 0.9439 1675170 TimTec1_005677 C(Oc1cccc(c1)c2nnc3ccc4ccccc4n23)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C02 compound treatment 0.415 0.124 17.08 0.348 0.0581 8.39 18.005 0.9464 1346658 TimTec1_005678 Fc1ccccc1C2Nc3ccc4ccccc4c3C5C=CCC52 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C03 compound treatment 0.287 -0.0044 -0.61 0.287 -0.00293 -0.42 -0.7294 -0.9844 3085628 TimTec1_005679 COC(C)n1cc(Br)c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C04 compound treatment 0.31 0.0186 2.57 0.313 0.0231 3.33 4.173 0.9918 1681244 TimTec1_005680 Cc1cc(Oc2cc(C#N)c3ccccc3n2)ccc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C05 compound treatment 0.289 -0.0024 -0.33 0.289 -9.33E-4 -0.13 -0.3298 -0.9214 3085667 TimTec1_005681 Fc1ccc2C(=O)N(N3CCOCC3)C(=O)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C06 compound treatment 0.287 -0.0044 -0.61 0.286 -0.00393 -0.57 -0.8316 -0.9994 1270347 TimTec1_005682 Cn1c(=N)n(CC(=O)C2(CC3CC4CC(C3)C2)C4)c5ccccc15 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C07 compound treatment 0.301 0.0096 1.33 0.298 0.00807 1.17 1.7617 0.9979 1454435 TimTec1_005683 CSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C08 compound treatment 0.29 -0.0014 -0.19 0.29 6.67E-5 0.01 -0.13 -0.6711 1371600 TimTec1_005684 Cc1ccc(cc1)C(=O)Cn2c(=N)n(C)c3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C09 compound treatment 0.299 0.0076 1.05 0.297 0.00707 1.02 1.4642 0.9999 1605543 TimTec1_005685 CSC1=NC2(Cc3ccccc13)CCCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C10 compound treatment 0.308 0.0166 2.29 0.315 0.0251 3.62 4.1819 0.9757 1564745 TimTec1_005686 CC(C)(O)C#Cc1ccc(cc1)C(=O)NCC(c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C11 compound treatment 0.33 0.0386 5.33 0.321 0.0311 4.49 6.9438 0.9963 3085653 TimTec1_005687 O=C(Nc1ccccc1)OCC23COC(N3C(OC2)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C12 compound treatment 0.308 0.0166 2.29 0.308 0.0181 2.61 3.4669 0.9979 1696532 TimTec1_005688 O=C1N(C(Nc2ccccc12)c3cccs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C13 compound treatment 0.322 0.0306 4.23 0.321 0.0311 4.49 6.1623 0.9996 3211537 TimTec1_005689 Cc1ccc(/N=C/2\NC(=O)C(Cc3cccc(c3)C(F)(F)F)S2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C14 compound treatment 0.323 0.0316 4.37 0.317 0.0271 3.91 5.8515 0.9985 1190215 TimTec1_005690 CC(C1Nc2ccccc2C(=O)N1c3ccccc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C15 compound treatment 0.291 -4.0E-4 -0.06 0.289 -9.33E-4 -0.13 -0.1344 -0.9225 1378935 TimTec1_005691 CCOC(=O)c1c(NC(=O)CSc2ncccn2)sc3CCCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C16 compound treatment 0.316 0.0246 3.4 0.323 0.0331 4.78 5.7805 0.9861 1327450 TimTec1_005692 CCC(=O)Nc1nonc1c2nc3ccccc3n2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C17 compound treatment 0.284 -0.0074 -1.02 0.29 6.67E-5 0.01 -0.7161 -0.7004 3211622 TimTec1_005693 CCC(=O)NC(Nc1sc2CCCCc2c1C#N)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C18 compound treatment 0.284 -0.0074 -1.02 0.285 -0.00493 -0.71 -1.2268 -0.9844 1168333 TimTec1_005694 CC(C)CCN1NC2(CCCCC2)NC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C19 compound treatment 0.303 0.0116 1.6 0.306 0.0161 2.32 2.7742 0.9837 3211623 TimTec1_005695 CN1C2=C(C(NC1=O)c3ccccc3)C(=O)N(C2)c4ccc(C)c(C)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C20 compound treatment 0.28 -0.0114 -1.57 0.28 -0.00993 -1.43 -2.1282 -0.9989 1532646 TimTec1_005696 Cn1nccc1C(=O)NCCN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C21 compound treatment 0.316 0.0246 3.4 0.316 0.0261 3.77 5.0655 0.9987 1534811 TimTec1_005697 COc1c(O)ccc2c(OC)c3ccoc3nc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C22 compound treatment 0.287 -0.0044 -0.61 0.287 -0.00293 -0.42 -0.7294 -0.9844 3085660 TimTec1_005698 Cn1c2ccccc2c3nnc(SCc4ccc(F)cc4Cl)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C23 mock treatment 0.291 -4.0E-4 -0.06 0.291 0.00107 0.15 0.0699 0.4269 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 C24 positive control 0.292 6.0E-4 0.08 0.293 0.00307 0.44 0.3718 0.8251 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D01 compound treatment 0.323 0.0316 4.37 0.348 0.0581 8.39 9.0178 0.9537 3211624 TimTec1_005699 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3ccc(OC(F)(F)F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D02 compound treatment 0.289 -0.0024 -0.33 0.289 -9.33E-4 -0.13 -0.3298 -0.9214 3085662 TimTec1_005700 C(Sc1ncn[nH]1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D03 compound treatment 0.303 0.0116 1.6 0.301 0.0111 1.6 2.2635 1.0 3211625 TimTec1_005701 Cc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccccc4)/S2)c(C)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D04 compound treatment 0.278 -0.0134 -1.85 0.279 -0.0109 -1.58 -2.4257 -0.9969 3085663 TimTec1_005702 FC(F)(F)C(NCCc1c[nH]c2ccccc12)(NC(=O)c3ccccc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D05 compound treatment 0.336 0.0446 6.16 0.338 0.0481 6.94 9.2663 0.9982 3211626 TimTec1_005703 CCC1(C)OC(=Nc2ccccc21)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D06 compound treatment 0.317 0.0256 3.54 0.316 0.0261 3.77 5.1632 0.9995 1384761 TimTec1_005704 Oc1ccc(NC2=C(C(=O)c3ccccc3C2=O)n4nnc5ccccc45)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D07 compound treatment 0.453 0.162 22.33 0.432 0.142 20.52 30.2968 0.9991 1725838 TimTec1_005705 CSc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D08 compound treatment 0.286 -0.0054 -0.75 0.286 -0.00393 -0.57 -0.9293 -0.991 1630880 TimTec1_005706 Cn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D09 compound treatment 0.318 0.0266 3.67 0.319 0.0291 4.2 5.5673 0.9978 1339859 TimTec1_005707 COc1cc2ccccc2cc1C(=O)NCCC3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D10 compound treatment 0.298 0.0066 0.91 0.301 0.0111 1.6 1.7751 0.9646 1488964 TimTec1_005708 CC(C)(C)c1ccc(cc1)C23OC(=O)C(C)(C)C3OC(=O)C2(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D11 compound treatment 0.281 -0.0104 -1.44 0.281 -0.00893 -1.29 -1.9284 -0.9986 1458934 TimTec1_005709 C1CN(CCN1)C2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D12 compound treatment 0.455 0.164 22.6 0.455 0.165 23.84 32.8413 0.9996 3211627 TimTec1_005710 O=C/1NC(=S)N\C1=C\c2cc3ccccc3nc2N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D13 compound treatment 0.318 0.0266 3.67 0.324 0.0341 4.92 6.078 0.9897 1617853 TimTec1_005711 Cc1cccc(C)c1NC(=O)C2(CCCC2)N(Cc3ccccc3)C(=O)c4ccc(cc4)n5cnnn5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D14 compound treatment 0.279 -0.0124 -1.71 0.289 -9.33E-4 -0.13 -1.3067 -0.7604 1422235 TimTec1_005712 Brc1ccc(CC2(CCc3ccncc3)C(=O)NC(=O)NC2=O)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D15 compound treatment 0.352 0.0606 8.37 0.353 0.0631 9.11 12.3614 0.9991 3211628 TimTec1_005713 CCN(CC)c1ccc(cc1)C2(NN(C(=C2C#N)N)c3ccccc3)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D16 compound treatment 0.405 0.114 15.69 0.401 0.111 16.04 22.4415 0.9999 3085673 TimTec1_005714 C/C(=N\c1ccccc1)/C2=C(O)C=C(CC2c3ccco3)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D17 compound treatment 0.295 0.0036 0.5 0.295 0.00507 0.73 0.8692 0.9823 3211629 TimTec1_005715 Fc1ccc(CCN2C(=O)NC(=O)/C(=C\c3cccc4ccccc34)/C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D18 compound treatment 0.355 0.0636 8.79 0.346 0.0561 8.1 11.9395 0.9992 1524909 TimTec1_005716 COc1ccccc1c2nnc(o2)c3ccccc3O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D19 compound treatment 0.352 0.0606 8.37 0.351 0.0611 8.82 12.1571 0.9997 3211630 TimTec1_005717 COc1cccc(c1)c2cc(nc(SC3CC(=O)C4OCC3O4)n2)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D20 compound treatment 0.281 -0.0104 -1.44 0.282 -0.00793 -1.15 -1.8262 -0.9937 3085676 TimTec1_005718 FC(F)(F)c1cccc(c1)N2C(=O)CC(Cc3ccccc3)C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D21 compound treatment 0.331 0.0396 5.47 0.33 0.0401 5.79 7.9608 0.9996 3211631 TimTec1_005719 CC1(C)OC(=O)C(=Cc2cccn2c3ccc(cc3)S(=O)(=O)N)C(=O)O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D22 compound treatment 0.302 0.0106 1.46 0.303 0.0131 1.89 2.3701 0.9921 3085679 TimTec1_005720 Cc1cccc2nc(=S)n(C(=O)c3ccc(F)cc3)n12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D23 mock treatment 0.289 -0.0024 -0.33 0.288 -0.00193 -0.28 -0.4319 -0.9964 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 D24 positive control 0.291 -4.0E-4 -0.06 0.291 0.00107 0.15 0.0699 0.4269 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E01 compound treatment 0.283 -0.0084 -1.16 0.284 -0.00593 -0.86 -1.4266 -0.9889 3211632 TimTec1_005721 Cc1cc(F)c(F)c(C(=O)n2ccnc2)c1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E02 compound treatment 0.296 0.0046 0.64 0.298 0.00807 1.17 1.2733 0.9594 1584802 TimTec1_005722 O=C(CSc1ccccc1)Nc2c(oc3ccccc23)C(=O)C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E03 compound treatment 0.35 0.0586 8.1 0.346 0.0561 8.1 11.4511 1.0 3211633 TimTec1_005723 COCc1cc(C)nc2sc(C(=O)OC)c(N)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E04 compound treatment 0.356 0.0646 8.92 0.374 0.0841 12.14 14.8971 0.9885 3211634 TimTec1_005724 CC(C)COC(=O)C1=C(C)Nc2cc(ccc2S1)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E05 compound treatment 0.29 -0.0014 -0.19 0.291 0.00107 0.15 -0.0278 -0.1125 3085682 TimTec1_005725 Fc1ccc(COc2ccccc2/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E06 compound treatment 0.364 0.0726 10.03 0.364 0.0741 10.7 14.6572 0.9995 3211635 TimTec1_005726 CN(C)c1ccc(/C=C\2/Oc3c(ccc(O)c3O)C2=O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E07 compound treatment 0.365 0.0736 10.17 0.371 0.0811 11.71 15.4698 0.9975 3211636 TimTec1_005727 CCn/1c(cs\c1=N\c2cc(OC)c(Cl)cc2OC)c3ccc(F)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E08 compound treatment 0.298 0.0066 0.91 0.297 0.00707 1.02 1.3665 0.9984 1668810 TimTec1_005728 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(Cc4ccccc4)O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E09 compound treatment 0.389 0.0976 13.48 0.384 0.0941 13.59 19.1421 1.0 1468867 TimTec1_005729 NS(=O)(=O)c1ccc(N=NN2CCCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E10 compound treatment 0.372 0.0806 11.13 0.363 0.0731 10.55 15.3365 0.9996 1221615 TimTec1_005730 CCc1ccc2cc(cn2c1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E11 compound treatment 0.279 -0.0124 -1.71 0.28 -0.00993 -1.43 -2.2259 -0.9961 3211637 TimTec1_005731 CC1SC(N(C1=O)c2ccccc2)c3ccc(Br)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E12 compound treatment 0.328 0.0366 5.06 0.327 0.0371 5.35 7.3613 0.9996 1203111 TimTec1_005732 Cc1cc(C(=O)O)c(C#N)c(N)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E13 compound treatment 0.304 0.0126 1.74 0.301 0.0111 1.6 2.3612 0.9991 3211638 TimTec1_005733 NC(=NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1)N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E14 compound treatment 0.277 -0.0144 -1.99 0.274 -0.0159 -2.3 -3.0341 -0.9974 3085709 TimTec1_005734 Cc1nc2ccccc2c(=O)n1c3ccc4OC(F)(F)Oc4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E15 compound treatment 0.279 -0.0124 -1.71 0.282 -0.00793 -1.15 -2.0216 -0.9809 3085711 TimTec1_005735 C/C(=C/C(=O)C1CC1)/C2CC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E16 compound treatment 0.308 0.0166 2.29 0.314 0.0241 3.48 4.0797 0.9796 1198283 TimTec1_005736 CC(C(=O)Nc1ccc2OCCOc2c1)n3nnc(n3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E17 compound treatment 0.361 0.0696 9.62 0.356 0.0661 9.54 13.547 1.0 1200453 TimTec1_005737 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E18 compound treatment 0.28 -0.0114 -1.57 0.281 -0.00893 -1.29 -2.0261 -0.9951 1488913 TimTec1_005738 CCCc1cc(O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E19 compound treatment 0.279 -0.0124 -1.71 0.277 -0.0129 -1.87 -2.5323 -0.9991 1378082 TimTec1_005739 CCOC(=O)C1(CCN(CC1)C(=O)c2ccccc2O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E20 compound treatment 0.284 -0.0074 -1.02 0.284 -0.00593 -0.86 -1.3289 -0.9962 1283200 TimTec1_005740 CC(C)N1C2OC(OC2N(C(C)C)S1(=O)=O)C3OC4C(O3)N(C(C)C)S(=O)(=O)N4C(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E21 compound treatment 0.285 -0.0064 -0.88 0.283 -0.00693 -1.0 -1.3334 -0.9981 1315806 TimTec1_005741 CC(=O)Oc1ccc(C)cc1n2nc3ccccc3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E22 compound treatment 0.509 0.218 30.06 0.516 0.226 32.65 44.3469 0.9991 3085715 TimTec1_005742 COc1ccccc1N/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E23 mock treatment 0.289 -0.0024 -0.33 0.289 -9.33E-4 -0.13 -0.3298 -0.9214 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 E24 positive control 0.292 6.0E-4 0.08 0.292 0.00207 0.3 0.2697 0.8705 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F01 compound treatment 0.288 -0.0034 -0.47 0.288 -0.00193 -0.28 -0.5296 -0.9692 1415787 TimTec1_005743 O=C(Cn1nnc(n1)c2ccc3OCOc3c2)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F02 compound treatment 0.351 0.0596 8.23 0.357 0.0671 9.69 12.6723 0.9967 1291024 TimTec1_005744 Cc1[nH]c2ccccc2c1CCNC(=O)c3cc4cc(Br)ccc4oc3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F03 compound treatment 0.305 0.0136 1.88 0.304 0.0141 2.03 2.7653 0.9992 3085718 TimTec1_005745 FC(F)(F)c1nnc(S)n1/N=C/c2ccc(Cl)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F04 compound treatment 0.285 -0.0064 -0.88 0.284 -0.00593 -0.86 -1.2312 -0.9999 1647381 TimTec1_005746 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)NCc3ccco3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F05 compound treatment 0.286 -0.0054 -0.75 0.285 -0.00493 -0.71 -1.0314 -0.9997 1416263 TimTec1_005747 Cc1c(NC(=O)C2CCCC2)c(=O)n(c3ccccc3)n1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F06 compound treatment 0.366 0.0746 10.31 0.37 0.0801 11.57 15.4654 0.9983 3211747 TimTec1_005748 Cc1cc(S)c2n(Cc3ccc(Cl)cc3Cl)nc[n+]2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F07 compound treatment 0.29 -0.0014 -0.19 0.289 -9.33E-4 -0.13 -0.2321 -0.9844 1581088 TimTec1_005749 Fc1cccc(Cl)c1C2N3CCCCN23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F08 compound treatment 0.328 0.0366 5.06 0.326 0.0361 5.21 7.2592 0.9999 1406168 TimTec1_005750 COC(=O)c1ccc(CSc2nnc3c4ccccc4n(C)c3n2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F09 compound treatment 0.303 0.0116 1.6 0.304 0.0141 2.03 2.5699 0.9931 3211748 TimTec1_005751 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)Nc3nn(nc3C(=O)N)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F10 compound treatment 0.282 -0.0094 -1.3 0.282 -0.00793 -1.15 -1.7286 -0.9981 3087784 TimTec1_005752 CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3)c4cc(Br)ccc4O)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F11 compound treatment 0.279 -0.0124 -1.71 0.277 -0.0129 -1.87 -2.5323 -0.9991 3211749 TimTec1_005753 N#CCC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F12 compound treatment 0.34 0.0486 6.71 0.328 0.0381 5.5 8.6357 0.9951 1605647 TimTec1_005754 COc1ccc(cc1OC)C2C(Oc3ccc(Cl)cc3C)C(=O)N2c4ccc(C)c(C)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F13 compound treatment 0.286 -0.0054 -0.75 0.282 -0.00793 -1.15 -1.3378 -0.9784 3087785 TimTec1_005755 C[S+](C)c1c(O)n(c2ccccc2F)c(=O)[nH]c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F14 compound treatment 0.288 -0.0034 -0.47 0.278 -0.0119 -1.72 -1.551 -0.8681 1201797 TimTec1_005756 Fc1cc(Cl)c(cc1F)C(=O)NC2C3CC4CC(C3)CC2C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F15 compound treatment 0.279 -0.0124 -1.71 0.275 -0.0149 -2.16 -2.7366 -0.9935 1326307 TimTec1_005757 CC(Sc1nc(N)cc(N)n1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F16 compound treatment 0.347 0.0556 7.68 0.347 0.0571 8.24 11.2601 0.9994 1664927 TimTec1_005758 C=CCn1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F17 compound treatment 0.282 -0.0094 -1.3 0.283 -0.00693 -1.0 -1.6264 -0.9918 3087786 TimTec1_005759 CC(Nc1nc(F)cc(=O)[nH]1)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F18 compound treatment 0.425 0.134 18.46 0.419 0.129 18.64 26.2337 1.0 3211750 TimTec1_005760 CCOC(=O)/C=C/1\NC(C)(C)Cc2cc(OC)c(O)cc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F19 compound treatment 0.314 0.0226 3.12 0.31 0.0201 2.9 4.2573 0.9993 3211751 TimTec1_005761 O=C(CSc1nnnn1c2ccccc2)NCCC3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F20 compound treatment 0.281 -0.0104 -1.44 0.278 -0.0119 -1.72 -2.2348 -0.9959 3087787 TimTec1_005762 CC1SC2(CCCCC2)N(C1=O)c3cc(C)cc(C)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F21 compound treatment 0.295 0.0036 0.5 0.282 -0.00793 -1.15 -0.4586 -0.3671 3211752 TimTec1_005763 CC(=O)NC(NCCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F22 compound treatment 0.365 0.0736 10.17 0.33 0.0401 5.79 11.2822 0.9643 1523330 TimTec1_005764 O=C(Oc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F23 mock treatment 0.292 6.0E-4 0.08 0.289 -9.33E-4 -0.13 -0.0367 -0.232 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 F24 positive control 0.293 0.0016 0.22 0.291 0.00107 0.15 0.2652 0.9844 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G01 compound treatment 0.292 6.0E-4 0.08 0.291 0.00107 0.15 0.1676 0.9577 3087788 TimTec1_005765 Fc1ccccc1c2nnc3ccc(cn23)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G02 compound treatment 0.287 -0.0044 -0.61 0.286 -0.00393 -0.57 -0.8316 -0.9994 3211753 TimTec1_005766 CN1C(=O)N(C)C2(N=C3SCC(=O)N3NC12c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G03 compound treatment 0.443 0.152 20.94 0.444 0.154 22.25 30.5456 0.9995 1444799 TimTec1_005767 OC1=C(C(N(C1=O)c2cccnc2)c3ccccc3)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G04 compound treatment 0.301 0.0096 1.33 0.3 0.0101 1.45 1.966 0.9989 1457617 TimTec1_005768 O=C(N1N=CCC1c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G05 compound treatment 0.329 0.0376 5.19 0.338 0.0481 6.94 8.5825 0.9898 1406350 TimTec1_005769 Clc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc45)sc3c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G06 compound treatment 0.307 0.0156 2.16 0.307 0.0171 2.47 3.2671 0.9978 1302719 TimTec1_005770 COC(=O)c1ccccc1NCNc2ccccc2C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G07 compound treatment 0.294 0.0026 0.36 0.29 6.67E-5 0.01 0.2608 0.7258 1261268 TimTec1_005771 CCCC(=C1C(=O)NC(=O)NC1=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G08 compound treatment 0.307 0.0156 2.16 0.322 0.0321 4.63 4.7992 0.9394 1028239 TimTec1_005772 S=c1sscc1c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G09 compound treatment 0.287 -0.0044 -0.61 0.284 -0.00593 -0.86 -1.0358 -0.9858 3211754 TimTec1_005773 CCOC(=O)Cc1nc(C)cs1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G10 compound treatment 0.283 -0.0084 -1.16 0.28 -0.00993 -1.43 -1.8352 -0.9945 1366551 TimTec1_005774 CCC1C(OC(=O)C(C)(C)C1=O)c2cccc(Br)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G11 compound treatment 0.282 -0.0094 -1.3 0.281 -0.00893 -1.29 -1.8307 -1.0 3087789 TimTec1_005775 CC(=O)OC(C)(C)C#CCN1CCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G12 compound treatment 0.316 0.0246 3.4 0.318 0.0281 4.05 5.2698 0.9962 3211755 TimTec1_005776 O=C/1Nc2ccccc2\C1=C/3\NC(=S)N(C3=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G13 compound treatment 0.288 -0.0034 -0.47 0.284 -0.00593 -0.86 -0.9382 -0.9599 3087790 TimTec1_005777 CCOC1=NOC2C3CCC(C3)C21 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G14 compound treatment 0.278 -0.0134 -1.85 0.275 -0.0149 -2.16 -2.8343 -0.9971 3211756 TimTec1_005778 COc1ccc(cc1)C2OCC(C)(CO2)C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G15 compound treatment 0.284 -0.0074 -1.02 0.279 -0.0109 -1.58 -1.8396 -0.9778 3087791 TimTec1_005779 Nc1ccc(OC(F)(F)F)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G16 compound treatment 0.286 -0.0054 -0.75 0.282 -0.00793 -1.15 -1.3378 -0.9784 1233416 TimTec1_005780 C(Sc1nnnn1c2ccc3OCOc3c2)C4CC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G17 compound treatment 0.287 -0.0044 -0.61 0.284 -0.00593 -0.86 -1.0358 -0.9858 1922264 TimTec1_005781 CC1(C)COC(O)(CC1=O)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G18 compound treatment 0.34 0.0486 6.71 0.345 0.0551 7.95 10.372 0.9964 1589793 TimTec1_005782 CCc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(cc4)N(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G19 compound treatment 0.287 -0.0044 -0.61 0.28 -0.00993 -1.43 -1.4444 -0.9269 3087792 TimTec1_005783 CSC1=NC2C(N1)N(C)C(=O)N2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G20 compound treatment 0.28 -0.0114 -1.57 0.276 -0.0139 -2.01 -2.5368 -0.9926 1362774 TimTec1_005784 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(O2)c4cccnc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G21 compound treatment 0.287 -0.0044 -0.61 0.282 -0.00793 -1.15 -1.2401 -0.956 3087793 TimTec1_005785 O=C(Oc1ccc(cc1)c2cnc3ccccc3n2)/C=C/c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G22 compound treatment 0.285 -0.0064 -0.88 0.282 -0.00793 -1.15 -1.4355 -0.9918 1511555 TimTec1_005786 Clc1ccc2oc(=O)n(C(=O)NC3CCCCC3)c2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G23 mock treatment 0.29 -0.0014 -0.19 0.287 -0.00293 -0.42 -0.4364 -0.9369 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 G24 positive control 0.292 6.0E-4 0.08 0.291 0.00107 0.15 0.1676 0.9577 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H01 compound treatment 0.291 -4.0E-4 -0.06 0.293 0.00307 0.44 0.2741 0.6141 1788039 TimTec1_005787 Fc1ccccc1c2nnn(CC(=O)N3CCCCC3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H02 compound treatment 0.29 -0.0014 -0.19 0.289 -9.33E-4 -0.13 -0.2321 -0.9844 1578958 TimTec1_005788 COc1ccc(Cl)cc1S(=O)(=O)N2CCN(CC2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H03 compound treatment 0.292 6.0E-4 0.08 0.29 6.67E-5 0.01 0.0654 0.784 3087794 TimTec1_005789 COc1cc2CC(C)(C)N=C(NC(C)C(=O)O)c2cc1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H04 compound treatment 0.487 0.196 27.02 0.49 0.2 28.9 39.5422 0.9994 3087795 TimTec1_005790 NCCN1C(=O)S/C(=C/c2cccs2)/C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H05 compound treatment 0.288 -0.0034 -0.47 0.285 -0.00493 -0.71 -0.836 -0.9795 1701075 TimTec1_005791 CCn1c(=N)n(CC(=O)c2cccs2)c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H06 compound treatment 0.293 0.0016 0.22 0.289 -9.33E-4 -0.13 0.061 0.2355 1332043 TimTec1_005792 COC(=O)NC1CSCC1OC(=O)CCCN2C(=O)c3ccccc3C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H07 compound treatment 0.288 -0.0034 -0.47 0.285 -0.00493 -0.71 -0.836 -0.9795 3087798 TimTec1_005793 COc1nsc(SC)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H08 compound treatment 0.292 6.0E-4 0.08 0.289 -9.33E-4 -0.13 -0.0367 -0.232 1015156 TimTec1_005794 COc1ccc(Cl)cc1NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H09 compound treatment 0.32 0.0286 3.95 0.324 0.0341 4.92 6.2734 0.9941 1397048 TimTec1_005795 COc1cc2ccccc2cc1C(=O)NC(C)Cc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H10 compound treatment 0.339 0.0476 6.58 0.33 0.0401 5.79 8.7423 0.998 3087801 TimTec1_005796 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4c(F)cccc4F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H11 compound treatment 0.319 0.0276 3.81 0.327 0.0371 5.35 6.4821 0.9862 1338227 TimTec1_005797 COc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccccc3F)c4ccccc4)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H12 compound treatment 0.328 0.0366 5.06 0.326 0.0361 5.21 7.2592 0.9999 1493728 TimTec1_005798 C1Oc2ccc(cc2O1)c3cc4ccccn4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H13 compound treatment 0.304 0.0126 1.74 0.302 0.0121 1.74 2.4633 1.0 1440128 TimTec1_005799 COc1cc(NC(=O)NC2(CC2)c3ccccc3)c(OC)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H14 compound treatment 0.303 0.0116 1.6 0.303 0.0131 1.89 2.4678 0.9967 1272978 TimTec1_005800 Cc1cc(NS(=O)(=O)c2ccccc2)cc(c1O)S(=O)(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H15 compound treatment 0.285 -0.0064 -0.88 0.28 -0.00993 -1.43 -1.6398 -0.9729 3211757 TimTec1_005801 Cc1cc(Cl)nc(NN)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H16 compound treatment 0.292 6.0E-4 0.08 0.317 0.0271 3.91 2.8232 0.7219 1520603 TimTec1_005802 Cn1c2ccc(Br)cc2c3nnc(SCc4ccc5nonc5c4)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H17 compound treatment 0.294 0.0026 0.36 0.29 6.67E-5 0.01 0.2608 0.7258 1486800 TimTec1_005803 CN(C)CP(=O)(O)CCn1c2ccccc2c3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H18 compound treatment 0.288 -0.0034 -0.47 0.284 -0.00593 -0.86 -0.9382 -0.9599 1194716 TimTec1_005804 OC(=O)C1Sc2c(sc(=O)n2Cc3ccccc3)C4C1C(=O)Oc5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H19 compound treatment 0.287 -0.0044 -0.61 0.285 -0.00493 -0.71 -0.9337 -0.9969 1203354 TimTec1_005805 Nc1nnc(CCCn2c(=O)oc3ccccc23)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H20 compound treatment 0.353 0.0616 8.51 0.346 0.0561 8.1 11.7441 0.9997 3087859 TimTec1_005806 CC/N=C\1/S/C(=C/c2ccc(o2)c3ccc(F)cc3)/C(=O)N1CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H21 compound treatment 0.304 0.0126 1.74 0.301 0.0111 1.6 2.3612 0.9991 1544104 TimTec1_005807 CN(C)c1ccc(cc1)C2OC(=O)C(C)(C)C(=O)C2(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H22 compound treatment 0.336 0.0446 6.16 0.329 0.0391 5.64 8.3471 0.999 3211853 TimTec1_005808 CCCn1c2ccccc2c3nnc(SCC(=O)NCc4ccc5OCOc5c4)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H23 mock treatment 0.29 -0.0014 -0.19 0.287 -0.00293 -0.42 -0.4364 -0.9369 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 H24 positive control 0.294 0.0026 0.36 0.293 0.00307 0.44 0.5672 0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I01 compound treatment 0.304 0.0126 1.74 0.302 0.0121 1.74 2.4633 1.0 1315061 TimTec1_005809 CCOC1(C)N(Nc2ccccc2C(=O)CC)c3ccccc3C1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I02 compound treatment 0.291 -4.0E-4 -0.06 0.288 -0.00193 -0.28 -0.2365 -0.8309 1011005 TimTec1_005810 OC(=O)CSc1ccccc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I03 compound treatment 0.289 -0.0024 -0.33 0.287 -0.00293 -0.42 -0.5341 -0.9926 3211854 TimTec1_005811 CC1(C)OC(=O)N(Nc2ccccc2)C1(C)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I04 compound treatment 0.289 -0.0024 -0.33 0.286 -0.00393 -0.57 -0.6362 -0.9671 3087863 TimTec1_005812 Cc1c(Cl)cccc1NN 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I05 compound treatment 0.327 0.0356 4.92 0.326 0.0361 5.21 7.1615 0.9996 1462704 TimTec1_005813 CC(C)(C)NC(=O)CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I06 compound treatment 0.288 -0.0034 -0.47 0.285 -0.00493 -0.71 -0.836 -0.9795 1663326 TimTec1_005814 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)Nc3ccccc3C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I07 compound treatment 0.405 0.114 15.69 0.401 0.111 16.04 22.4415 0.9999 3211855 TimTec1_005815 C1C/C(=C\c2nc3ccccc3[nH]2)/C(=C1)N4CCOCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I08 compound treatment 0.321 0.0296 4.09 0.314 0.0241 3.48 5.3497 0.9967 1375813 TimTec1_005816 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I09 compound treatment 0.285 -0.0064 -0.88 0.28 -0.00993 -1.43 -1.6398 -0.9729 3087867 TimTec1_005817 COC(=O)c1c(CSC(=N)N)nc2n(Cc3ccccc3)c4ccccc4n12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I10 compound treatment 0.302 0.0106 1.46 0.297 0.00707 1.02 1.7573 0.9844 3211856 TimTec1_005818 CC1=C(OC(=O)c2ccccc2)C(C)(C)C(OC1=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I11 compound treatment 0.282 -0.0094 -1.3 0.277 -0.0129 -1.87 -2.2393 -0.9842 3087868 TimTec1_005819 COC(=O)c1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)O)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I12 compound treatment 0.374 0.0826 11.41 0.358 0.0681 9.83 15.0212 0.9972 3211857 TimTec1_005820 COc1ccc(/C=N/c2nnc(c3ccccc3)c(n2)c4ccccc4)c(C(=O)O)c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I13 compound treatment 0.322 0.0306 4.23 0.325 0.0351 5.07 6.5709 0.996 3087871 TimTec1_005821 CC1CN(CN2C(=O)/C(=N\c3ccc4ccccc4c3)/c5ccccc25)CC(C)O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I14 compound treatment 0.284 -0.0074 -1.02 0.283 -0.00693 -1.0 -1.431 -0.9999 1190190 TimTec1_005822 CC(=O)OC1c2ccccc2NC(c3ccccc3)C1(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I15 compound treatment 0.375 0.0836 11.55 0.37 0.0801 11.57 16.3446 1.0 1442650 TimTec1_005823 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccs2)SCC(=O)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I16 compound treatment 0.349 0.0576 7.96 0.343 0.0531 7.67 11.047 0.9998 3087873 TimTec1_005824 SC1=C(C#N)C2(CCCCC2)C(C(=N)N1)c3nc(cs3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I17 compound treatment 0.429 0.138 19.01 0.429 0.139 20.09 27.6459 0.9996 1201213 TimTec1_005825 OC(=O)c1ccc(N=NN2CCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I18 compound treatment 0.308 0.0166 2.29 0.306 0.0161 2.32 3.2626 1.0 3211858 TimTec1_005826 CSc1ccc(cc1)S(=O)(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I19 compound treatment 0.34 0.0486 6.71 0.337 0.0471 6.8 9.5549 1.0 1656330 TimTec1_005827 CC(C)(CN1CCN(CC1)C(c2ccccc2)c3ccccc3)NS(=O)(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I20 compound treatment 0.3 0.0086 1.19 0.297 0.00707 1.02 1.5619 0.9971 1594685 TimTec1_005828 CC1C(C#N)(C#N)C2(C#N)C(OC1(C)OC2=N)c3ccncc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I21 compound treatment 0.314 0.0226 3.12 0.352 0.0621 8.97 8.5471 0.9003 3211859 TimTec1_005829 O=C/1N(CN2CCN(CC2)c3ccccc3)c4ccccc4\C1=N\c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I22 compound treatment 0.349 0.0576 7.96 0.358 0.0681 9.83 12.579 0.9945 1426903 TimTec1_005830 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(O)c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I23 mock treatment 0.295 0.0036 0.5 0.291 0.00107 0.15 0.4606 0.8847 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 I24 positive control 0.296 0.0046 0.64 0.295 0.00507 0.73 0.9669 0.9975 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J01 compound treatment 0.295 0.0036 0.5 0.294 0.00407 0.59 0.767 0.9966 1380440 TimTec1_005831 CC(C)(CO)NC1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J02 compound treatment 0.302 0.0106 1.46 0.303 0.0131 1.89 2.3701 0.9921 1328534 TimTec1_005832 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J03 compound treatment 0.658 0.367 50.65 0.668 0.378 54.61 74.4274 0.9993 3211860 TimTec1_005833 FC(F)(F)C1=CC(=NCCN1)c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J04 compound treatment 0.302 0.0106 1.46 0.3 0.0101 1.45 2.0637 1.0 1159735 TimTec1_005834 CN(C)P1(=O)Nc2ccccc2S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J05 compound treatment 0.292 6.0E-4 0.08 0.289 -9.33E-4 -0.13 -0.0367 -0.232 1421447 TimTec1_005835 CC(C)(O)C1(C)NCCc2ccccc21 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J06 compound treatment 0.345 0.0536 7.4 0.355 0.0651 9.4 11.8819 0.993 1178221 TimTec1_005836 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3ccc(C)c(C)c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J07 compound treatment 0.292 6.0E-4 0.08 0.288 -0.00193 -0.28 -0.1389 -0.4767 1709992 TimTec1_005837 CC1(C)CC(CC(C)(C)N1)NCc2ccco2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J08 compound treatment 0.29 -0.0014 -0.19 0.287 -0.00293 -0.42 -0.4364 -0.9369 1603180 TimTec1_005838 O=C(NC1CCCCC1)C2CC(=O)OC32CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J09 compound treatment 0.299 0.0076 1.05 0.291 0.00107 0.15 0.8514 0.8023 1526847 TimTec1_005839 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccccc5C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J10 compound treatment 0.343 0.0516 7.13 0.341 0.0511 7.38 10.2566 0.9999 3211861 TimTec1_005840 CCc1nc2sc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c(N)c2cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J11 compound treatment 0.285 -0.0064 -0.88 0.281 -0.00893 -1.29 -1.5376 -0.983 1564041 TimTec1_005841 CCN(C(=O)Cn1nnc(n1)c2ccc3OCOc3c2)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J12 compound treatment 0.291 -4.0E-4 -0.06 0.286 -0.00393 -0.57 -0.4408 -0.7722 3087925 TimTec1_005842 FC(F)(F)c1nnc2SCC(=Nn12)c3ccc(Cl)cc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J13 compound treatment 0.397 0.106 14.59 0.388 0.0981 14.17 20.3322 0.9999 3211862 TimTec1_005843 CCN1C(=O)C2NN=C(C2C1=O)C(=O)c3nc(Cl)ccc3Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J14 compound treatment 0.428 0.137 18.87 0.414 0.124 17.92 26.0161 0.9997 1209557 TimTec1_005844 COc1ccc(cc1)C(=O)Nc2cc(C)c(O)c(c2C)S(=O)(=O)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J15 compound treatment 0.36 0.0686 9.48 0.363 0.0731 10.55 14.1643 0.9986 3211863 TimTec1_005845 Sc1nc(SCCOc2ccccc2)nc3ccccc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J16 compound treatment 0.355 0.0636 8.79 0.355 0.0651 9.4 12.8587 0.9994 3087928 TimTec1_005846 CC(C)(C)C(=O)/C=C/1\NCCN\C1=C/C(=O)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J17 compound treatment 0.289 -0.0024 -0.33 0.286 -0.00393 -0.57 -0.6362 -0.9671 1272266 TimTec1_005847 OC(=O)C(Cc1ccco1)P(=O)(O)CN2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J18 compound treatment 0.346 0.0546 7.54 0.34 0.0501 7.23 10.4475 0.9998 1688384 TimTec1_005848 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCC3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J19 compound treatment 0.293 0.0016 0.22 0.311 0.0211 3.04 2.308 0.7565 1696945 TimTec1_005849 COc1cccc(c1)C(=O)Nc2cccc(C)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J20 compound treatment 0.371 0.0796 11.0 0.366 0.0761 10.99 15.5453 1.0 3087931 TimTec1_005850 Cc1cccn2cc(cc12)c3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J21 compound treatment 0.286 -0.0054 -0.75 0.283 -0.00693 -1.0 -1.2357 -0.9895 1142933 TimTec1_005851 Cc1ccc(cc1)C(=O)C2OC(=O)C(C)(C)C(=O)C2(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J22 compound treatment 0.357 0.0656 9.06 0.346 0.0561 8.1 12.1349 0.9984 3211864 TimTec1_005852 COc1cccc2cc(C(=O)NCCc3c(C)[nH]c4ccc(OC(F)(F)F)cc34)c(=O)oc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J23 mock treatment 0.293 0.0016 0.22 0.291 0.00107 0.15 0.2652 0.9844 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 J24 positive control 0.297 0.0056 0.77 0.294 0.00407 0.59 0.9624 0.9908 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K01 compound treatment 0.34 0.0486 6.71 0.36 0.0701 10.12 11.9041 0.9801 1683560 TimTec1_005853 CCn1c(nc2ccccc12)C(O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K02 compound treatment 0.294 0.0026 0.36 0.29 6.67E-5 0.01 0.2608 0.7258 3088026 TimTec1_005854 O=C1CSC2=NCN(CN12)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K03 compound treatment 0.351 0.0596 8.23 0.355 0.0651 9.4 12.468 0.9978 3087964 TimTec1_005855 CCOC(=O)C1=C(C)NC(=NC1c2ccc(OC(=O)C)c(OC)c2)SC(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K04 compound treatment 0.292 6.0E-4 0.08 0.288 -0.00193 -0.28 -0.1389 -0.4767 3087966 TimTec1_005856 CC(=O)NCCOc1cccc2cccnc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K05 compound treatment 0.311 0.0196 2.71 0.313 0.0231 3.33 4.2707 0.9947 1264565 TimTec1_005857 Cn1c(SCc2ccc(F)c3ccccc23)nc4ccccc4c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K06 compound treatment 0.294 0.0026 0.36 0.288 -0.00193 -0.28 0.0565 0.1242 3211865 TimTec1_005858 Clc1ccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K07 compound treatment 0.283 -0.0084 -1.16 0.277 -0.0129 -1.87 -2.1416 -0.9738 1638757 TimTec1_005859 CCN(CC)P1(=O)COc2ccccc2OC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K08 compound treatment 0.292 6.0E-4 0.08 0.285 -0.00493 -0.71 -0.4453 -0.6207 3211945 TimTec1_005860 CCC1CCC2(CC1)SCC(=O)N2c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K09 compound treatment 0.284 -0.0074 -1.02 0.278 -0.0119 -1.72 -1.9417 -0.9689 1385466 TimTec1_005861 COc1ccc(cc1)N(C)C(=O)C2COc3ccccc3O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K10 compound treatment 0.301 0.0096 1.33 0.295 0.00507 0.73 1.4553 0.9607 1301245 TimTec1_005862 Cc1ccc(NS(=O)(=O)c2c(C)ccc3nsnc23)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K11 compound treatment 0.367 0.0756 10.44 0.363 0.0731 10.55 14.8481 1.0 3087971 TimTec1_005863 CN(C)/C=N\c1ccc2nonc2c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K12 compound treatment 0.31 0.0186 2.57 0.311 0.0211 3.04 3.9687 0.9965 1432844 TimTec1_005864 CCOC(=O)c1c(CN2CCCC2)n(C)c3cc(Br)c(OC)cc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K13 compound treatment 0.282 -0.0094 -1.3 0.275 -0.0149 -2.16 -2.4435 -0.9705 3211946 TimTec1_005865 CSC1=NC2(CC(Oc3cc(O)ccc32)c4ccccc4)CC(C)(C)N1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K14 compound treatment 0.613 0.322 44.43 0.534 0.244 35.25 56.3449 0.9934 3087973 TimTec1_005866 CC(=O)N1C(=O)/C(=C\c2cccnc2)/NC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K15 compound treatment 0.327 0.0356 4.92 0.317 0.0271 3.91 6.2422 0.9935 1685221 TimTec1_005867 CCOC(=O)c1c(NC(=O)CSc2nccn2C)sc3CC(C)CCc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K16 compound treatment 0.361 0.0696 9.62 0.361 0.0711 10.27 14.0577 0.9995 3087975 TimTec1_005868 Oc1ccccc1c2cc(nn2Cc3ccc(Cl)cc3)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K17 compound treatment 0.401 0.11 15.14 0.427 0.137 19.8 24.7063 0.9912 1551420 TimTec1_005869 COC(=O)c1ccc(N=NN2CCCCCC2)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K18 compound treatment 0.344 0.0526 7.27 0.333 0.0431 6.22 9.5371 0.997 1545682 TimTec1_005870 COc1ccc(cc1)C2CC(=O)Oc3ccc(cc23)C(C)(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K19 compound treatment 0.289 -0.0024 -0.33 0.286 -0.00393 -0.57 -0.6362 -0.9671 1253632 TimTec1_005871 O=C(N(Cc1ccccc1)c2ccccn2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K20 compound treatment 0.287 -0.0044 -0.61 0.281 -0.00893 -1.29 -1.3423 -0.941 3211947 TimTec1_005872 COc1nc(OC)nc(n1)n2cnc(NC(=O)Nc3cccc(Cl)c3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K21 compound treatment 0.339 0.0476 6.58 0.345 0.0551 7.95 10.2744 0.9955 1118061 TimTec1_005873 Sc1nc2-c3ccccc3CC(C4CCCCC4)c2c(=O)[nH]1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K22 compound treatment 0.284 -0.0074 -1.02 0.283 -0.00693 -1.0 -1.431 -0.9999 3211948 TimTec1_005874 CCC(C#N)C1(CC2CC3CC(C2)C1)C3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K23 mock treatment 0.292 6.0E-4 0.08 0.292 0.00207 0.3 0.2697 0.8705 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 K24 positive control 0.293 0.0016 0.22 0.291 0.00107 0.15 0.2652 0.9844 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L01 compound treatment 0.285 -0.0064 -0.88 0.285 -0.00493 -0.71 -1.1291 -0.9943 3087980 TimTec1_005875 COC(=O)c1ccc(cc1)C2OCC(C)(C)CO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L02 compound treatment 0.288 -0.0034 -0.47 0.287 -0.00293 -0.42 -0.6317 -0.9987 1135137 TimTec1_005876 CCOc1ccc(CCNS(=O)(=O)c2c(C)cc(C)cc2C)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L03 compound treatment 0.284 -0.0074 -1.02 0.281 -0.00893 -1.29 -1.6353 -0.9933 3211949 TimTec1_005877 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)N)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L04 compound treatment 0.29 -0.0014 -0.19 0.284 -0.00593 -0.86 -0.7428 -0.8454 1515423 TimTec1_005878 CCOc1nc(Cl)nc(n1)N2CCCCC2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L05 compound treatment 0.291 -4.0E-4 -0.06 0.285 -0.00493 -0.71 -0.543 -0.7597 3088028 TimTec1_005879 COc1ccc(cc1)C(=O)NC(N2CCCCC2c3cccnc3)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L06 compound treatment 0.294 0.0026 0.36 0.285 -0.00493 -0.71 -0.2499 -0.3131 1732675 TimTec1_005880 CCOc1ccc(CC(=O)Nc2ccccc2)cc1OCC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L07 compound treatment 0.304 0.0126 1.74 0.295 0.00507 0.73 1.7484 0.9259 1230635 TimTec1_005881 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccc(O)cc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L08 compound treatment 0.29 -0.0014 -0.19 0.283 -0.00693 -1.0 -0.8449 -0.8284 1233176 TimTec1_005882 CCNC(=O)C1CC(=O)OC21CCCCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L09 compound treatment 0.291 -4.0E-4 -0.06 0.284 -0.00593 -0.86 -0.6451 -0.7511 1157682 TimTec1_005883 COCc1cc(C)nc(SCC(=O)N2CCCCC2)c1C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L10 compound treatment 0.278 -0.0134 -1.85 0.274 -0.0159 -2.3 -2.9364 -0.9942 3088032 TimTec1_005884 CC(=O)ON1C(C)(C)C=C(C(=O)N)C1(C)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L11 compound treatment 0.282 -0.0094 -1.3 0.286 -0.00393 -0.57 -1.32 -0.9312 3211950 TimTec1_005885 COc1ccccc1n2c(S)nnc2Cc3ccc(Cl)cc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L12 compound treatment 0.306 0.0146 2.02 0.297 0.00707 1.02 2.148 0.9502 1274328 TimTec1_005886 COc1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L13 compound treatment 0.308 0.0166 2.29 0.307 0.0171 2.47 3.3648 0.9993 3211951 TimTec1_005887 COC(=O)C1=CN(CC2(CC3CC4CC(C3)C2)C4)C=C(C1c5ccc(F)cc5)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L14 compound treatment 0.341 0.0496 6.85 0.336 0.0461 6.65 9.5505 0.9999 1513069 TimTec1_005888 CC(C)c1c(NC(=O)c2ccc(Cl)cc2)cc(C)c(O)c1S(=O)(=O)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L15 compound treatment 0.304 0.0126 1.74 0.306 0.0161 2.32 2.8719 0.99 1273520 TimTec1_005889 CCn1c(SCCn2c(=S)n(C)c3ccccc23)nc4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L16 compound treatment 0.289 -0.0024 -0.33 0.282 -0.00793 -1.15 -1.0447 -0.8758 1715744 TimTec1_005890 C(N1CCCC1)c2cc3ccccc3c4COCc42 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L17 compound treatment 0.319 0.0276 3.81 0.312 0.0221 3.19 4.95 0.996 1402014 TimTec1_005891 Cc1nc2cccc(C(=O)Oc3ccc(cc3)C(C)(C)C)c2o1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L18 compound treatment 0.348 0.0566 7.82 0.333 0.0431 6.22 9.9279 0.9936 1594146 TimTec1_005892 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCCC3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L19 compound treatment 0.285 -0.0064 -0.88 0.28 -0.00993 -1.43 -1.6398 -0.9729 3088038 TimTec1_005893 CCc1nnc(NC(=O)CSc2nnc(c3cccs3)n2CC=C)s1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L20 compound treatment 0.315 0.0236 3.26 0.309 0.0191 2.75 4.2529 0.9965 3211952 TimTec1_005894 CCN(CC)c1ccc(C=C2C(=O)OC(OC2=O)c3ccccc3)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L21 compound treatment 0.507 0.216 29.79 0.506 0.216 31.21 43.1302 0.9997 3088039 TimTec1_005895 OC(=O)/C(=C/C(=O)c1ccccc1)/Nc2ccc(OC(F)(F)F)cc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L22 compound treatment 0.286 -0.0054 -0.75 0.282 -0.00793 -1.15 -1.3378 -0.9784 1788194 TimTec1_005896 CCOC(=O)c1c(C)c(NC(=O)C)c(C)n1C(=O)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L23 mock treatment 0.294 0.0026 0.36 0.293 0.00307 0.44 0.5672 0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 L24 positive control 0.292 6.0E-4 0.08 0.29 6.67E-5 0.01 0.0654 0.784 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M01 compound treatment 0.291 -4.0E-4 -0.06 0.294 0.00407 0.59 0.3763 0.6378 1430182 TimTec1_005897 Cc1cc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccc(C)cc3)no1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M02 compound treatment 0.291 -4.0E-4 -0.06 0.291 0.00107 0.15 0.0699 0.4269 1516860 TimTec1_005898 CCN1C2OC3OC4C(OC3OC2N(CC)S1(=O)=O)N(CC)S(=O)(=O)N4CC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M03 compound treatment 0.328 0.0366 5.06 0.323 0.0331 4.78 6.9527 0.9996 1315988 TimTec1_005899 Clc1ccccc1NCn2nc(c3ccccc3)n(CC=C)c2=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M04 compound treatment 0.291 -4.0E-4 -0.06 0.287 -0.00293 -0.42 -0.3387 -0.7926 3088042 TimTec1_005900 CCC(=O)NC(Nc1sc(C)c(CC)c1C#N)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M05 compound treatment 0.293 0.0016 0.22 0.287 -0.00293 -0.42 -0.1433 -0.2999 3211953 TimTec1_005901 CC(C)C1C(=C(N)Oc2n[nH]c(C)c12)C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M06 compound treatment 0.297 0.0056 0.77 0.289 -9.33E-4 -0.13 0.4517 0.5752 1171314 TimTec1_005902 COc1ccc(OC)c(CNc2ccc3n(C)c(C)nc3c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M07 compound treatment 0.364 0.0726 10.03 0.357 0.0671 9.69 13.9422 0.9998 3088045 TimTec1_005903 CCOC(=O)C1=C(C)NC(=NC1c2ccccc2)SCC(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M08 compound treatment 0.294 0.0026 0.36 0.281 -0.00893 -1.29 -0.6584 -0.4916 1705094 TimTec1_005904 OC(=O)Cc1c(Sc2ccccc2)c3ccccc3n1Cc4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M09 compound treatment 0.295 0.0036 0.5 0.298 0.00807 1.17 1.1756 0.9279 3211954 TimTec1_005905 CN(C)c1ccc(/C=C/2\C(=O)N(N=C2C(=O)Nc3ccccc3)c4ccccc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M10 compound treatment 0.387 0.0956 13.21 0.385 0.0951 13.73 19.0489 0.9998 1621165 TimTec1_005906 O1c2ccccc2N=C(c3ccccc3)c4ccccc14 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M11 compound treatment 0.291 -4.0E-4 -0.06 0.292 0.00207 0.3 0.172 0.5666 1640716 TimTec1_005907 CCN(CC)C(=O)c1cn(nc1C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M12 compound treatment 0.286 -0.0054 -0.75 0.284 -0.00593 -0.86 -1.1335 -0.9976 3211955 TimTec1_005908 OC(=O)C1CC(=O)N(CCc2ccccc2)/C(=N/CCc3ccccc3)/S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M13 compound treatment 0.306 0.0146 2.02 0.303 0.0131 1.89 2.7608 0.9994 3088114 TimTec1_005909 CCCN1C(=O)/C(=C/C=C\2/Sc3ccccc3N2CCO)/SC1=S 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M14 compound treatment 0.341 0.0496 6.85 0.332 0.0421 6.08 9.1419 0.9982 1416853 TimTec1_005910 CCCCC(=O)Nc1ccc(cc1)c2csc(n2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M15 compound treatment 0.303 0.0116 1.6 0.301 0.0111 1.6 2.2635 1.0 3088116 TimTec1_005911 FC(F)(F)c1cccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M16 compound treatment 0.353 0.0616 8.51 0.376 0.0861 12.43 14.8083 0.9829 1117685 TimTec1_005912 CN(C)c1ccc(cc1)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M17 compound treatment 0.292 6.0E-4 0.08 0.28 -0.00993 -1.43 -0.956 -0.6651 1411622 TimTec1_005913 O=C(N(c1ccccc1)c2ccccc2)c3ccccc3C(=O)N4CCCCC4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M18 compound treatment 0.296 0.0046 0.64 0.29 6.67E-5 0.01 0.4562 0.7177 1119974 TimTec1_005914 COc1ccc(cc1)c2nc(SCc3ccccc3C#N)[nH]c(=O)c2C#N 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M19 compound treatment 0.346 0.0546 7.54 0.349 0.0591 8.53 11.3667 0.9981 1518985 TimTec1_005915 CC(C1C(=C(N)Oc2c1c(=O)oc3ccccc23)C#N)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M20 compound treatment 0.331 0.0396 5.47 0.335 0.0451 6.51 8.4715 0.9963 3088119 TimTec1_005916 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc3ccccc23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M21 compound treatment 0.284 -0.0074 -1.02 0.282 -0.00793 -1.15 -1.5332 -0.9984 1232476 TimTec1_005917 CC1CN(C(=O)C)c2ccccc2NC1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M22 compound treatment 0.36 0.0686 9.48 0.36 0.0701 10.12 13.8579 0.9995 1452888 TimTec1_005918 O=C1N(C(=O)c2cccc3cccc1c23)c4ccccc4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M23 mock treatment 0.294 0.0026 0.36 0.293 0.00307 0.44 0.5672 0.9946 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 M24 positive control 0.284 -0.0074 -1.02 0.286 -0.00393 -0.57 -1.1246 -0.9616 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N01 compound treatment 0.315 0.0236 3.26 0.307 0.0171 2.47 4.0486 0.9905 1241281 TimTec1_005919 COc1cc(NC(=O)c2cc3ccccc3cc2OCC(=O)NC(C)(C)C)c(OC)cc1Cl 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N02 compound treatment 0.316 0.0246 3.4 0.314 0.0241 3.48 4.8612 0.9999 3088122 TimTec1_005920 CCn/1cccc\c1=N/P2(=S)OCCO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N03 compound treatment 0.332 0.0406 5.61 0.327 0.0371 5.35 7.752 0.9997 1595949 TimTec1_005921 OC1=C(C(N(CCc2ccccc2)C1=O)c3ccccc3)C(=O)c4cccs4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N04 compound treatment 0.317 0.0256 3.54 0.315 0.0251 3.62 5.0611 0.9999 1572095 TimTec1_005922 COCc1cc(C)nc2[nH]nc(N)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N05 compound treatment 0.29 -0.0014 -0.19 0.286 -0.00393 -0.57 -0.5385 -0.8973 3212011 TimTec1_005923 O=C(NCCOc1ccccc1)/C=C/c2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N06 compound treatment 0.285 -0.0064 -0.88 0.281 -0.00893 -1.29 -1.5376 -0.983 3212012 TimTec1_005924 CCOC(=O)c1cn(nc1N)C2CC(=O)C3OCC2O3.CCOC(=O)c1cn(nc1N)C2CC(O)(O)C3OCC2O3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N07 compound treatment 0.288 -0.0034 -0.47 0.283 -0.00693 -1.0 -1.0403 -0.9405 3088126 TimTec1_005925 NC[C@@H]1CCCN2CCCC[C@H]12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N08 compound treatment 0.278 -0.0134 -1.85 0.274 -0.0159 -2.3 -2.9364 -0.9942 1354761 TimTec1_005926 CCC(C)NCc1ccc(o1)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N09 compound treatment 0.307 0.0156 2.16 0.303 0.0131 1.89 2.8585 0.9978 1518220 TimTec1_005927 CSC1=NC(=C(C(=O)Nc2ccccc2)C3(CCCCC3)C1C(=O)N)C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N10 compound treatment 0.286 -0.0054 -0.75 0.283 -0.00693 -1.0 -1.2357 -0.9895 3212013 TimTec1_005928 OC1(O)CC(C2COC1O2)n3nc(c4ccco4)n(CC=C)c3=S.C=CCn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N11 compound treatment 0.369 0.0776 10.72 0.367 0.0771 11.13 15.452 0.9998 3088130 TimTec1_005929 Cc1cc2CC(C)(C)N/C(=C/C(=O)N)/c2cc1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N12 compound treatment 0.283 -0.0084 -1.16 0.283 -0.00693 -1.0 -1.5287 -0.9973 1138138 TimTec1_005930 CCOC(=O)c1[nH]c(C)c(CNc2ccccc2)c1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N13 compound treatment 0.288 -0.0034 -0.47 0.285 -0.00493 -0.71 -0.836 -0.9795 1675612 TimTec1_005931 COc1nonc1n2nnc(C(=O)c3ccccc3)c2C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N14 compound treatment 0.334 0.0426 5.89 0.337 0.0471 6.8 8.9688 0.9974 1140939 TimTec1_005932 CCCc1c(C)[nH]c2nc3ccccc3n2c1=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N15 compound treatment 0.281 -0.0104 -1.44 0.278 -0.0119 -1.72 -2.2348 -0.9959 3088132 TimTec1_005933 Clc1ccccc1c2nnc3cccc(Cl)n23 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N16 compound treatment 0.309 0.0176 2.43 0.315 0.0251 3.62 4.2796 0.9812 1219341 TimTec1_005934 CCN(C(=O)c1c(C)c(Cl)c(C)nc1Oc2ccc(F)cc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N17 compound treatment 0.286 -0.0054 -0.75 0.284 -0.00593 -0.86 -1.1335 -0.9976 1518508 TimTec1_005935 CC(=O)N(CC1(CC2CC3CC(C2)C1)C3)C4CC(=O)N(C4=O)c5cccc(Cl)c5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N18 compound treatment 0.282 -0.0094 -1.3 0.278 -0.0119 -1.72 -2.1371 -0.9903 3088204 TimTec1_005936 Cn1nc(cc1Cl)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N19 compound treatment 0.525 0.234 32.27 0.522 0.232 33.52 46.5228 0.9998 3088206 TimTec1_005937 Cc1ccc(N/C(=C/C(=O)c2ccccc2)/C(=O)O)cc1Br 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N20 compound treatment 0.306 0.0146 2.02 0.301 0.0111 1.6 2.5566 0.9934 3088207 TimTec1_005938 CC(C)(C)C1(C)OC(=O)C(=Cc2ccc(Br)o2)C(=O)O1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N21 compound treatment 0.39 0.0986 13.62 0.387 0.0971 14.02 19.5462 0.9999 3212014 TimTec1_005939 COCCN1C=C(C(C(=C1)C(=O)OC)c2cccs2)C(=O)OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N22 compound treatment 0.336 0.0446 6.16 0.334 0.0441 6.37 8.8578 0.9999 3212015 TimTec1_005940 CN/1CCC\C1=C\C=C\2/SC(=S)NC2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N23 mock treatment 0.291 -4.0E-4 -0.06 0.289 -9.33E-4 -0.13 -0.1344 -0.9225 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 N24 positive control 0.289 -0.0024 -0.33 0.288 -0.00193 -0.28 -0.4319 -0.9964 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O01 compound treatment 0.316 0.0246 3.4 0.315 0.0251 3.62 4.9634 0.9995 1199249 TimTec1_005941 CCCn1c2ccccc2c3nnc(SCC(=O)NC(C)c4ccccc4)nc13 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O02 compound treatment 0.292 6.0E-4 0.08 0.291 0.00107 0.15 0.1676 0.9577 1786664 TimTec1_005942 CC(C)c1cc(=O)n2nc(N)[nH]c2n1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O03 compound treatment 0.33 0.0386 5.33 0.326 0.0361 5.21 7.4545 0.9999 3212016 TimTec1_005943 Fc1ccccc1COc2ccccc2/C=C\3/SC(=N)NC3=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O04 compound treatment 0.349 0.0576 7.96 0.34 0.0501 7.23 10.7405 0.9989 1724360 TimTec1_005944 c1c(nc2nc(c3ccccc3)c(nn12)c4ccccc4)c5ccccc5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O05 compound treatment 0.298 0.0066 0.91 0.293 0.00307 0.44 0.958 0.945 3088212 TimTec1_005945 O=C(CSC1=NC(CC(=O)N1)c2ccccc2)Nc3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O06 compound treatment 0.296 0.0046 0.64 0.297 0.00707 1.02 1.1711 0.974 1025381 TimTec1_005946 COc1ccc2CC3N(CCc4cc5OCOc5cc34)Cc2c1OC 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O07 compound treatment 0.329 0.0376 5.19 0.326 0.0361 5.21 7.3568 1.0 1512733 TimTec1_005947 COc1ccc(cc1)C2=C(C)C(c3cccs3)c4ccccc4O2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O08 compound treatment 0.29 -0.0014 -0.19 0.293 0.00307 0.44 0.1765 0.3651 3088214 TimTec1_005948 COC(=O)c1ccc(cc1)C2OCCCO2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O09 compound treatment 0.414 0.123 16.94 0.41 0.12 17.34 24.2399 0.9999 3212017 TimTec1_005949 CCN(CC)N=Nc1n[nH]c2nc(C)cc(C)c12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O10 compound treatment 0.283 -0.0084 -1.16 0.283 -0.00693 -1.0 -1.5287 -0.9973 1112286 TimTec1_005950 CC(=O)Nc1ccc(Cl)cc1C(=O)O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O11 compound treatment 0.447 0.156 21.5 0.431 0.141 20.38 29.6085 0.9996 3212018 TimTec1_005951 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4c[nH]c5ccccc45 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O12 compound treatment 0.292 6.0E-4 0.08 0.291 0.00107 0.15 0.1676 0.9577 3212019 TimTec1_005952 COc1cc(OC)c(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)c(OC)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O13 compound treatment 0.281 -0.0104 -1.44 0.281 -0.00893 -1.29 -1.9284 -0.9986 1583863 TimTec1_005953 CCOC(=O)C1(CCN(Cc2cccc(c2)C(=O)O)CC1)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O14 compound treatment 0.297 0.0056 0.77 0.295 0.00507 0.73 1.0646 0.9996 3212020 TimTec1_005954 COC(=O)c1c(NC(NC(=O)C)(C(F)(F)F)C(F)(F)F)sc2CN(C)CCc12 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O15 compound treatment 0.358 0.0666 9.2 0.337 0.0471 6.8 11.3133 0.9889 1330742 TimTec1_005955 COc1ccc(cc1)C(=O)c2sc3nc(cc(c4cccs4)c3c2N)c5cccs5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O16 compound treatment 0.285 -0.0064 -0.88 0.286 -0.00393 -0.57 -1.0269 -0.9771 1008206 TimTec1_005956 NNc1ccc(Br)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O17 compound treatment 0.343 0.0516 7.13 0.344 0.0541 7.81 10.563 0.999 3212021 TimTec1_005957 C/N=C\1/S/C(=C\c2sccc2C)/C(=O)N1C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O18 compound treatment 0.283 -0.0084 -1.16 0.281 -0.00893 -1.29 -1.733 -0.9986 1627835 TimTec1_005958 OC(C(=O)NN1CCCCC1)(c2ccsc2)c3ccsc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O19 compound treatment 0.292 6.0E-4 0.08 0.296 0.00607 0.88 0.6783 0.7706 3088220 TimTec1_005959 C/C(=N/O)/C1CCCCCCCCCCC1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O20 compound treatment 0.279 -0.0124 -1.71 0.277 -0.0129 -1.87 -2.5323 -0.9991 3212022 TimTec1_005960 Fc1cccc(C(=O)N2CCCCC2)c1F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O21 compound treatment 0.294 0.0026 0.36 0.29 6.67E-5 0.01 0.2608 0.7258 1373583 TimTec1_005961 Clc1ccc(cc1)C2(CC(=O)N3CCCCC3)C(=O)c4ccccc4C2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O22 compound treatment 0.283 -0.0084 -1.16 0.28 -0.00993 -1.43 -1.8352 -0.9945 1018702 TimTec1_005962 Oc1ccccc1C(=O)N2CCOCC2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O23 mock treatment 0.293 0.0016 0.22 0.291 0.00107 0.15 0.2652 0.9844 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 O24 positive control 0.285 -0.0064 -0.88 0.285 -0.00493 -0.71 -1.1291 -0.9943 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P01 compound treatment 0.294 0.0026 0.36 0.296 0.00607 0.88 0.8736 0.9225 1707498 TimTec1_005963 COc1ccc(C(=O)c2ccccc2)c(OCC(=O)NC3(CC4CC5CC(C4)C3)C5)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P02 compound treatment 0.288 -0.0034 -0.47 0.291 0.00107 0.15 -0.2232 -0.4515 3088297 TimTec1_005964 CC1(C)COP(=S)(OC1)N(C2=NCCC2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P03 compound treatment 0.287 -0.0044 -0.61 0.288 -0.00193 -0.28 -0.6273 -0.9377 3212023 TimTec1_005965 CCC1CC(O)C(C)C(C)S1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P04 compound treatment 0.293 0.0016 0.22 0.29 6.67E-5 0.01 0.1631 0.7372 3088299 TimTec1_005966 Oc1c(Cl)cc(Cl)cc1C(O)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P05 compound treatment 0.3 0.0086 1.19 0.297 0.00707 1.02 1.5619 0.9971 1497087 TimTec1_005967 COc1ccccc1n2c(CSc3ccccn3)nc4ccccc4c2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P06 compound treatment 0.315 0.0236 3.26 0.311 0.0211 3.04 4.4571 0.9994 3088301 TimTec1_005968 FC(F)(F)c1ccc(cc1)C(=O)NCCc2ccccc2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P07 compound treatment 0.333 0.0416 5.75 0.326 0.0361 5.21 7.7476 0.9988 3212024 TimTec1_005969 Brc1cccc(CSCC(=O)Nc2ccc3ccccc3c2)c1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P08 compound treatment 0.346 0.0546 7.54 0.333 0.0431 6.22 9.7325 0.9954 3212086 TimTec1_005970 Cc1cc(Cl)ccc1OC2C(N(C2=O)c3cccc(c3)C(F)(F)F)c4ccc5OCOc5c4 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P09 compound treatment 0.294 0.0026 0.36 0.294 0.00407 0.59 0.6694 0.9721 1275002 TimTec1_005971 CC(NC(=O)NC1(CC1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P10 compound treatment 0.285 -0.0064 -0.88 0.287 -0.00293 -0.42 -0.9248 -0.9432 1579554 TimTec1_005972 COc1ccc(cc1OC)C2SCC(=O)N2CCN3CCCCC3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P11 compound treatment 0.332 0.0406 5.61 0.329 0.0391 5.64 7.9563 1.0 3088305 TimTec1_005973 CNc1nc(cc(n1)C(F)(F)F)c2cccs2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P12 compound treatment 0.283 -0.0084 -1.16 0.287 -0.00293 -0.42 -1.1202 -0.9067 1420064 TimTec1_005974 Fc1ccccc1c2nnn(CC(=O)NCc3ccc4OCOc4c3)n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P13 compound treatment 0.287 -0.0044 -0.61 0.288 -0.00193 -0.28 -0.6273 -0.9377 1669226 TimTec1_005975 CCOC(=O)C1=C(N)CC(NC1c2ccccc2)c3ccccc3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P14 compound treatment 0.283 -0.0084 -1.16 0.285 -0.00493 -0.71 -1.3245 -0.9726 3088307 TimTec1_005976 COc1cc(ccc1n2cnnn2)n3cnnn3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P15 compound treatment 0.277 -0.0144 -1.99 0.276 -0.0139 -2.01 -2.8298 -1.0 1638981 TimTec1_005977 COc1ccc(NC(=O)C2(CCCCC2)N(C(=O)Cn3nnnc3N)c4ccc(OC)cc4)cc1 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P16 compound treatment 0.285 -0.0064 -0.88 0.285 -0.00493 -0.71 -1.1291 -0.9943 1387660 TimTec1_005978 CN(C)c1ccc(cc1)C(N2C(CC2=O)c3ccco3)C(=O)Nc4c(C)cccc4C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P17 compound treatment 0.284 -0.0074 -1.02 0.285 -0.00493 -0.71 -1.2268 -0.9844 1166206 TimTec1_005979 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)N(CC=C)CC=C 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P18 compound treatment 0.293 0.0016 0.22 0.292 0.00207 0.3 0.3674 0.9891 3088310 TimTec1_005980 Cc1ccccc1CSc2nnc3c4ccccc4n(CC=C)c3n2 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P19 compound treatment 0.299 0.0076 1.05 0.299 0.00907 1.31 1.6685 0.994 3212087 TimTec1_005981 CC(=O)NC(NCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P20 compound treatment 0.282 -0.0094 -1.3 0.282 -0.00793 -1.15 -1.7286 -0.9981 3212088 TimTec1_005982 Brc1ccc2nc(oc(=O)c2c1)c3ccc4C(=O)N(C5CCCCC5)C(=O)c4c3 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P21 compound treatment 0.43 0.139 19.15 0.438 0.148 21.39 28.6628 0.9985 1700737 TimTec1_005983 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(Nc4ccccc4)c5ccccc35 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P22 compound treatment 0.291 -4.0E-4 -0.06 0.288 -0.00193 -0.28 -0.2365 -0.8309 3212089 TimTec1_005984 CN1CCC(CC1)OC(=O)c2cc3cc(Br)ccc3oc2=O 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P23 mock treatment 0.285 -0.0064 -0.88 0.285 -0.00493 -0.71 -1.1291 -0.9943 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.2079 P24 positive control 0.292 6.0E-4 0.08 0.292 0.00207 0.3 0.2697 0.8705 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A01 mock treatment 0.215 -0.00748 -1.03 0.219 -0.00551 -0.8 -1.2935 -0.9917 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A02 mock treatment 0.217 -0.00548 -0.76 0.217 -0.00751 -1.08 -1.3024 -0.9845 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A03 mock treatment 0.219 -0.00348 -0.48 0.211 -0.0135 -1.95 -1.7199 -0.8557 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A04 mock treatment 0.216 -0.00648 -0.9 0.208 -0.0165 -2.38 -2.3194 -0.9105 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A05 mock treatment 0.213 -0.00948 -1.31 0.219 -0.00551 -0.8 -1.4889 -0.9715 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A06 mock treatment 0.216 -0.00648 -0.9 0.214 -0.0105 -1.52 -1.7065 -0.9683 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A07 mock treatment 0.218 -0.00448 -0.62 0.21 -0.0145 -2.1 -1.9197 -0.8784 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A08 mock treatment 0.212 -0.0105 -1.45 0.214 -0.0105 -1.52 -2.0973 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A09 mock treatment 0.211 -0.0115 -1.59 0.216 -0.00851 -1.23 -1.9907 -0.9921 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A10 mock treatment 0.208 -0.0145 -2.0 0.215 -0.00951 -1.37 -2.3859 -0.9832 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A11 mock treatment 0.215 -0.00748 -1.03 0.212 -0.0125 -1.81 -2.0085 -0.9648 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A12 mock treatment 0.217 -0.00548 -0.76 0.224 -5.11E-4 -0.07 -0.5875 -0.7724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A13 mock treatment 0.214 -0.00848 -1.17 0.213 -0.0115 -1.66 -2.0041 -0.9853 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A14 mock treatment 0.209 -0.0135 -1.86 0.214 -0.0105 -1.52 -2.3904 -0.9949 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A15 mock treatment 0.208 -0.0145 -2.0 0.212 -0.0125 -1.81 -2.6923 -0.9987 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A16 mock treatment 0.207 -0.0155 -2.14 0.211 -0.0135 -1.95 -2.8921 -0.999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A17 mock treatment 0.207 -0.0155 -2.14 0.21 -0.0145 -2.1 -2.9943 -0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A18 mock treatment 0.212 -0.0105 -1.45 0.218 -0.00651 -0.94 -1.6887 -0.9782 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A19 mock treatment 0.214 -0.00848 -1.17 0.215 -0.00951 -1.37 -1.7998 -0.9969 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A20 mock treatment 0.215 -0.00748 -1.03 0.214 -0.0105 -1.52 -1.8042 -0.9824 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A21 mock treatment 0.208 -0.0145 -2.0 0.214 -0.0105 -1.52 -2.488 -0.9907 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A22 mock treatment 0.211 -0.0115 -1.59 0.213 -0.0115 -1.66 -2.2971 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A23 mock treatment 0.213 -0.00948 -1.31 0.217 -0.00751 -1.08 -1.6932 -0.9956 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base A24 mock treatment 0.211 -0.0115 -1.59 0.212 -0.0125 -1.81 -2.3993 -0.9979 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B01 mock treatment 0.229 0.00652 0.9 0.229 0.00449 0.65 1.0955 0.987 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B02 mock treatment 0.228 0.00552 0.76 0.225 4.89E-4 0.07 0.5892 0.7693 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B03 mock treatment 0.231 0.00852 1.18 0.228 0.00349 0.5 1.1887 0.9284 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B04 mock treatment 0.23 0.00752 1.04 0.222 -0.00251 -0.36 0.4782 0.4346 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B05 mock treatment 0.23 0.00752 1.04 0.226 0.00149 0.22 0.8867 0.8358 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B06 mock treatment 0.231 0.00852 1.18 0.226 0.00149 0.22 0.9844 0.8227 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B07 mock treatment 0.233 0.0105 1.45 0.228 0.00349 0.5 1.3841 0.8998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B08 mock treatment 0.234 0.0115 1.59 0.233 0.00849 1.23 1.9925 0.9917 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B09 mock treatment 0.23 0.00752 1.04 0.229 0.00449 0.65 1.1932 0.9743 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B10 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B11 mock treatment 0.222 -4.8E-4 -0.07 0.228 0.00349 0.5 0.3095 0.6089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B12 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B13 mock treatment 0.229 0.00652 0.9 0.234 0.00949 1.37 1.6062 0.9793 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B14 mock treatment 0.224 0.00152 0.21 0.222 -0.00251 -0.36 -0.1079 -0.2575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B15 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B16 mock treatment 0.228 0.00552 0.76 0.227 0.00249 0.36 0.7935 0.9411 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B17 mock treatment 0.229 0.00652 0.9 0.231 0.00649 0.94 1.2998 0.9998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B18 mock treatment 0.227 0.00452 0.62 0.228 0.00349 0.5 0.798 0.9944 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B19 mock treatment 0.226 0.00352 0.49 0.23 0.00549 0.79 0.9046 0.9725 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B20 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B21 mock treatment 0.226 0.00352 0.49 0.227 0.00249 0.36 0.5981 0.989 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B22 mock treatment 0.227 0.00452 0.62 0.224 -5.11E-4 -0.07 0.3894 0.6193 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B23 mock treatment 0.229 0.00652 0.9 0.222 -0.00251 -0.36 0.3805 0.3919 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base B24 mock treatment 0.228 0.00552 0.76 0.224 -5.11E-4 -0.07 0.4871 0.6357 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C01 mock treatment 0.23 0.00752 1.04 0.231 0.00649 0.94 1.3974 0.9987 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C02 mock treatment 0.228 0.00552 0.76 0.226 0.00149 0.22 0.6914 0.8725 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C03 mock treatment 0.228 0.00552 0.76 0.225 4.89E-4 0.07 0.5892 0.7693 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C04 mock treatment 0.231 0.00852 1.18 0.225 4.89E-4 0.07 0.8823 0.7482 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C05 mock treatment 0.225 0.00252 0.35 0.22 -0.00451 -0.65 -0.2145 -0.2904 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C06 mock treatment 0.23 0.00752 1.04 0.227 0.00249 0.36 0.9889 0.8995 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C07 mock treatment 0.23 0.00752 1.04 0.231 0.00649 0.94 1.3974 0.9987 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C08 mock treatment 0.233 0.0105 1.45 0.23 0.00549 0.79 1.5884 0.9594 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C09 mock treatment 0.232 0.00952 1.32 0.227 0.00249 0.36 1.1843 0.8685 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C10 mock treatment 0.223 5.2E-4 0.07 0.222 -0.00251 -0.36 -0.2056 -0.5562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C11 mock treatment 0.224 0.00152 0.21 0.222 -0.00251 -0.36 -0.1079 -0.2575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C12 mock treatment 0.225 0.00252 0.35 0.226 0.00149 0.22 0.3983 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C13 mock treatment 0.228 0.00552 0.76 0.229 0.00449 0.65 0.9978 0.9967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C14 mock treatment 0.221 -0.00148 -0.2 0.223 -0.00151 -0.22 -0.2989 -0.9995 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C15 mock treatment 0.22 -0.00248 -0.34 0.224 -5.11E-4 -0.07 -0.2944 -0.8401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C16 mock treatment 0.227 0.00452 0.62 0.228 0.00349 0.5 0.798 0.9944 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C17 mock treatment 0.228 0.00552 0.76 0.229 0.00449 0.65 0.9978 0.9967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C18 mock treatment 0.229 0.00652 0.9 0.227 0.00249 0.36 0.8912 0.9189 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C19 mock treatment 0.227 0.00452 0.62 0.229 0.00449 0.65 0.9001 0.9998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C20 mock treatment 0.224 0.00152 0.21 0.226 0.00149 0.22 0.3006 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C21 mock treatment 0.223 5.2E-4 0.07 0.226 0.00149 0.22 0.2029 0.8947 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C22 mock treatment 0.227 0.00452 0.62 0.226 0.00149 0.22 0.5937 0.8989 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C23 mock treatment 0.225 0.00252 0.35 0.223 -0.00151 -0.22 0.0919 0.2236 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base C24 mock treatment 0.23 0.00752 1.04 0.226 0.00149 0.22 0.8867 0.8358 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D01 mock treatment 0.227 0.00452 0.62 0.229 0.00449 0.65 0.9001 0.9998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D02 mock treatment 0.226 0.00352 0.49 0.225 4.89E-4 0.07 0.3939 0.8015 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D03 mock treatment 0.228 0.00552 0.76 0.225 4.89E-4 0.07 0.5892 0.7693 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D04 mock treatment 0.22 -0.00248 -0.34 0.227 0.00249 0.36 0.012 0.0242 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D05 mock treatment 0.223 5.2E-4 0.07 0.223 -0.00151 -0.22 -0.1035 -0.4504 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D06 mock treatment 0.222 -4.8E-4 -0.07 0.223 -0.00151 -0.22 -0.2012 -0.8821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D07 mock treatment 0.228 0.00552 0.76 0.228 0.00349 0.5 0.8956 0.9798 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D08 mock treatment 0.227 0.00452 0.62 0.228 0.00349 0.5 0.798 0.9944 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D09 mock treatment 0.224 0.00152 0.21 0.216 -0.00851 -1.23 -0.7208 -0.5779 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D10 mock treatment 0.22 -0.00248 -0.34 0.22 -0.00451 -0.65 -0.703 -0.9549 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D11 mock treatment 0.22 -0.00248 -0.34 0.222 -0.00251 -0.36 -0.4987 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D12 mock treatment 0.224 0.00152 0.21 0.227 0.00249 0.36 0.4028 0.9672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D13 mock treatment 0.226 0.00352 0.49 0.224 -5.11E-4 -0.07 0.2917 0.5931 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D14 mock treatment 0.221 -0.00148 -0.2 0.226 0.00149 0.22 0.0076 0.0255 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D15 mock treatment 0.218 -0.00448 -0.62 0.217 -0.00751 -1.08 -1.2047 -0.9646 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D16 mock treatment 0.224 0.00152 0.21 0.229 0.00449 0.65 0.607 0.8906 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D17 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D18 mock treatment 0.225 0.00252 0.35 0.225 4.89E-4 0.07 0.2962 0.8336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D19 mock treatment 0.221 -0.00148 -0.2 0.224 -5.11E-4 -0.07 -0.1967 -0.9051 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D20 mock treatment 0.224 0.00152 0.21 0.225 4.89E-4 0.07 0.1985 0.8957 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D21 mock treatment 0.219 -0.00348 -0.48 0.222 -0.00251 -0.36 -0.5964 -0.9903 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D22 mock treatment 0.223 5.2E-4 0.07 0.221 -0.00351 -0.51 -0.3078 -0.6009 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D23 mock treatment 0.223 5.2E-4 0.07 0.225 4.89E-4 0.07 0.1008 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base D24 mock treatment 0.227 0.00452 0.62 0.229 0.00449 0.65 0.9001 0.9998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E01 mock treatment 0.223 5.2E-4 0.07 0.231 0.00649 0.94 0.7136 0.7591 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E02 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E03 mock treatment 0.228 0.00552 0.76 0.225 4.89E-4 0.07 0.5892 0.7693 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E04 mock treatment 0.223 5.2E-4 0.07 0.222 -0.00251 -0.36 -0.2056 -0.5562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E05 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E06 mock treatment 0.225 0.00252 0.35 0.224 -5.11E-4 -0.07 0.194 0.5452 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E07 mock treatment 0.228 0.00552 0.76 0.227 0.00249 0.36 0.7935 0.9411 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E08 mock treatment 0.228 0.00552 0.76 0.228 0.00349 0.5 0.8956 0.9798 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E09 mock treatment 0.227 0.00452 0.62 0.221 -0.00351 -0.51 0.083 0.1032 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E10 mock treatment 0.223 5.2E-4 0.07 0.221 -0.00351 -0.51 -0.3078 -0.6009 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E11 mock treatment 0.212 -0.0105 -1.45 0.22 -0.00451 -0.65 -1.4845 -0.935 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E12 mock treatment 0.224 0.00152 0.21 0.221 -0.00351 -0.51 -0.2101 -0.3827 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E13 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E14 mock treatment 0.213 -0.00948 -1.31 0.222 -0.00251 -0.36 -1.1825 -0.8702 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E15 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E16 mock treatment 0.221 -0.00148 -0.2 0.226 0.00149 0.22 0.0076 0.0255 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E17 mock treatment 0.222 -4.8E-4 -0.07 0.228 0.00349 0.5 0.3095 0.6089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E18 mock treatment 0.225 0.00252 0.35 0.23 0.00549 0.79 0.8069 0.9317 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E19 mock treatment 0.222 -4.8E-4 -0.07 0.223 -0.00151 -0.22 -0.2012 -0.8821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E20 mock treatment 0.22 -0.00248 -0.34 0.222 -0.00251 -0.36 -0.4987 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E21 mock treatment 0.221 -0.00148 -0.2 0.223 -0.00151 -0.22 -0.2989 -0.9995 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E22 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E23 mock treatment 0.222 -4.8E-4 -0.07 0.219 -0.00551 -0.8 -0.6097 -0.7633 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base E24 mock treatment 0.23 0.00752 1.04 0.225 4.89E-4 0.07 0.7846 0.7535 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F01 mock treatment 0.222 -4.8E-4 -0.07 0.228 0.00349 0.5 0.3095 0.6089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F02 mock treatment 0.222 -4.8E-4 -0.07 0.221 -0.00351 -0.51 -0.4054 -0.7928 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F03 mock treatment 0.225 0.00252 0.35 0.225 4.89E-4 0.07 0.2962 0.8336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F04 mock treatment 0.22 -0.00248 -0.34 0.225 4.89E-4 0.07 -0.1923 -0.5497 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F05 mock treatment 0.224 0.00152 0.21 0.222 -0.00251 -0.36 -0.1079 -0.2575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F06 mock treatment 0.226 0.00352 0.49 0.229 0.00449 0.65 0.8024 0.9899 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F07 mock treatment 0.225 0.00252 0.35 0.223 -0.00151 -0.22 0.0919 0.2236 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F08 mock treatment 0.227 0.00452 0.62 0.226 0.00149 0.22 0.5937 0.8989 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F09 mock treatment 0.218 -0.00448 -0.62 0.223 -0.00151 -0.22 -0.5919 -0.902 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F10 mock treatment 0.222 -4.8E-4 -0.07 0.218 -0.00651 -0.94 -0.7119 -0.7551 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F11 mock treatment 0.214 -0.00848 -1.17 0.22 -0.00451 -0.65 -1.2891 -0.9617 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F12 mock treatment 0.22 -0.00248 -0.34 0.221 -0.00351 -0.51 -0.6008 -0.9818 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F13 mock treatment 0.222 -4.8E-4 -0.07 0.225 4.89E-4 0.07 0.0031 0.0321 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F14 mock treatment 0.215 -0.00748 -1.03 0.222 -0.00251 -0.36 -0.9871 -0.9014 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F15 mock treatment 0.216 -0.00648 -0.9 0.22 -0.00451 -0.65 -1.0937 -0.9878 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F16 mock treatment 0.222 -4.8E-4 -0.07 0.228 0.00349 0.5 0.3095 0.6089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F17 mock treatment 0.222 -4.8E-4 -0.07 0.231 0.00649 0.94 0.6159 0.6555 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F18 mock treatment 0.224 0.00152 0.21 0.23 0.00549 0.79 0.7092 0.8646 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F19 mock treatment 0.224 0.00152 0.21 0.222 -0.00251 -0.36 -0.1079 -0.2575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F20 mock treatment 0.219 -0.00348 -0.48 0.223 -0.00151 -0.22 -0.4942 -0.9361 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F21 mock treatment 0.218 -0.00448 -0.62 0.22 -0.00451 -0.65 -0.8983 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F22 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F23 mock treatment 0.222 -4.8E-4 -0.07 0.221 -0.00351 -0.51 -0.4054 -0.7928 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base F24 mock treatment 0.23 0.00752 1.04 0.224 -5.11E-4 -0.07 0.6825 0.6552 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G01 mock treatment 0.226 0.00352 0.49 0.233 0.00849 1.23 1.211 0.918 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G02 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G03 mock treatment 0.221 -0.00148 -0.2 0.224 -5.11E-4 -0.07 -0.1967 -0.9051 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G04 mock treatment 0.226 0.00352 0.49 0.223 -0.00151 -0.22 0.1896 0.3557 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G05 mock treatment 0.223 5.2E-4 0.07 0.223 -0.00151 -0.22 -0.1035 -0.4504 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G06 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G07 mock treatment 0.226 0.00352 0.49 0.229 0.00449 0.65 0.8024 0.9899 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G08 mock treatment 0.228 0.00552 0.76 0.227 0.00249 0.36 0.7935 0.9411 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G09 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G10 mock treatment 0.22 -0.00248 -0.34 0.225 4.89E-4 0.07 -0.1923 -0.5497 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G11 mock treatment 0.217 -0.00548 -0.76 0.22 -0.00451 -0.65 -0.996 -0.9972 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G12 mock treatment 0.222 -4.8E-4 -0.07 0.226 0.00149 0.22 0.1052 0.4675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G13 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G14 mock treatment 0.216 -0.00648 -0.9 0.22 -0.00451 -0.65 -1.0937 -0.9878 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G15 mock treatment 0.22 -0.00248 -0.34 0.22 -0.00451 -0.65 -0.703 -0.9549 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G16 mock treatment 0.219 -0.00348 -0.48 0.222 -0.00251 -0.36 -0.5964 -0.9903 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G17 mock treatment 0.222 -4.8E-4 -0.07 0.227 0.00249 0.36 0.2074 0.5672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G18 mock treatment 0.225 0.00252 0.35 0.228 0.00349 0.5 0.6026 0.9837 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G19 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G20 mock treatment 0.217 -0.00548 -0.76 0.224 -5.11E-4 -0.07 -0.5875 -0.7724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G21 mock treatment 0.223 5.2E-4 0.07 0.224 -5.11E-4 -0.07 -0.0013 -0.013 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G22 mock treatment 0.222 -4.8E-4 -0.07 0.222 -0.00251 -0.36 -0.3033 -0.8227 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G23 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base G24 mock treatment 0.227 0.00452 0.62 0.225 4.89E-4 0.07 0.4915 0.7821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H01 mock treatment 0.229 0.00652 0.9 0.232 0.00749 1.08 1.4019 0.9959 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H02 mock treatment 0.224 0.00152 0.21 0.227 0.00249 0.36 0.4028 0.9672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H03 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H04 mock treatment 0.222 -4.8E-4 -0.07 0.225 4.89E-4 0.07 0.0031 0.0321 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H05 mock treatment 0.224 0.00152 0.21 0.225 4.89E-4 0.07 0.1985 0.8957 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H06 mock treatment 0.227 0.00452 0.62 0.226 0.00149 0.22 0.5937 0.8989 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H07 mock treatment 0.224 0.00152 0.21 0.23 0.00549 0.79 0.7092 0.8646 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H08 mock treatment 0.224 0.00152 0.21 0.225 4.89E-4 0.07 0.1985 0.8957 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H09 mock treatment 0.223 5.2E-4 0.07 0.219 -0.00551 -0.8 -0.512 -0.6407 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H10 mock treatment 0.218 -0.00448 -0.62 0.227 0.00249 0.36 -0.1834 -0.2562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H11 mock treatment 0.215 -0.00748 -1.03 0.22 -0.00451 -0.65 -1.1914 -0.9753 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H12 mock treatment 0.219 -0.00348 -0.48 0.224 -5.11E-4 -0.07 -0.3921 -0.8062 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H13 mock treatment 0.224 0.00152 0.21 0.22 -0.00451 -0.65 -0.3122 -0.4561 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H14 mock treatment 0.218 -0.00448 -0.62 0.223 -0.00151 -0.22 -0.5919 -0.902 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H15 mock treatment 0.218 -0.00448 -0.62 0.22 -0.00451 -0.65 -0.8983 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H16 mock treatment 0.22 -0.00248 -0.34 0.225 4.89E-4 0.07 -0.1923 -0.5497 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H17 mock treatment 0.223 5.2E-4 0.07 0.226 0.00149 0.22 0.2029 0.8947 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H18 mock treatment 0.22 -0.00248 -0.34 0.224 -5.11E-4 -0.07 -0.2944 -0.8401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H19 mock treatment 0.224 0.00152 0.21 0.223 -0.00151 -0.22 -0.0058 -0.0191 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H20 mock treatment 0.22 -0.00248 -0.34 0.221 -0.00351 -0.51 -0.6008 -0.9818 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H21 mock treatment 0.218 -0.00448 -0.62 0.219 -0.00551 -0.8 -1.0005 -0.9923 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H22 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H23 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base H24 mock treatment 0.228 0.00552 0.76 0.222 -0.00251 -0.36 0.2828 0.3349 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I01 mock treatment 0.228 0.00552 0.76 0.229 0.00449 0.65 0.9978 0.9967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I02 mock treatment 0.223 5.2E-4 0.07 0.224 -5.11E-4 -0.07 -0.0013 -0.013 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I03 mock treatment 0.225 0.00252 0.35 0.225 4.89E-4 0.07 0.2962 0.8336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I04 mock treatment 0.225 0.00252 0.35 0.221 -0.00351 -0.51 -0.1124 -0.1827 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I05 mock treatment 0.223 5.2E-4 0.07 0.225 4.89E-4 0.07 0.1008 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I06 mock treatment 0.226 0.00352 0.49 0.228 0.00349 0.5 0.7003 0.9998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I07 mock treatment 0.225 0.00252 0.35 0.228 0.00349 0.5 0.6026 0.9837 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I08 mock treatment 0.223 5.2E-4 0.07 0.222 -0.00251 -0.36 -0.2056 -0.5562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I09 mock treatment 0.223 5.2E-4 0.07 0.219 -0.00551 -0.8 -0.512 -0.6407 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I10 mock treatment 0.221 -0.00148 -0.2 0.221 -0.00351 -0.51 -0.5031 -0.9202 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I11 mock treatment 0.217 -0.00548 -0.76 0.223 -0.00151 -0.22 -0.6896 -0.8753 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I12 mock treatment 0.221 -0.00148 -0.2 0.225 4.89E-4 0.07 -0.0946 -0.4372 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I13 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I14 mock treatment 0.218 -0.00448 -0.62 0.221 -0.00351 -0.51 -0.7962 -0.9951 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I15 mock treatment 0.214 -0.00848 -1.17 0.218 -0.00651 -0.94 -1.4934 -0.9941 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I16 mock treatment 0.217 -0.00548 -0.76 0.224 -5.11E-4 -0.07 -0.5875 -0.7724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I17 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I18 mock treatment 0.226 0.00352 0.49 0.226 0.00149 0.22 0.496 0.9327 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I19 mock treatment 0.222 -4.8E-4 -0.07 0.225 4.89E-4 0.07 0.0031 0.0321 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I20 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I21 mock treatment 0.222 -4.8E-4 -0.07 0.221 -0.00351 -0.51 -0.4054 -0.7928 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I22 mock treatment 0.221 -0.00148 -0.2 0.226 0.00149 0.22 0.0076 0.0255 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I23 mock treatment 0.225 0.00252 0.35 0.224 -5.11E-4 -0.07 0.194 0.5452 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base I24 mock treatment 0.231 0.00852 1.18 0.223 -0.00151 -0.22 0.678 0.5664 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J01 mock treatment 0.23 0.00752 1.04 0.234 0.00949 1.37 1.7039 0.9907 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J02 mock treatment 0.229 0.00652 0.9 0.227 0.00249 0.36 0.8912 0.9189 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J03 mock treatment 0.226 0.00352 0.49 0.222 -0.00251 -0.36 0.0874 0.1441 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J04 mock treatment 0.221 -0.00148 -0.2 0.225 4.89E-4 0.07 -0.0946 -0.4372 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J05 mock treatment 0.225 0.00252 0.35 0.225 4.89E-4 0.07 0.2962 0.8336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J06 mock treatment 0.225 0.00252 0.35 0.233 0.00849 1.23 1.1133 0.8734 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J07 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J08 mock treatment 0.226 0.00352 0.49 0.23 0.00549 0.79 0.9046 0.9725 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J09 mock treatment 0.225 0.00252 0.35 0.221 -0.00351 -0.51 -0.1124 -0.1827 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J10 mock treatment 0.219 -0.00348 -0.48 0.225 4.89E-4 0.07 -0.29 -0.5967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J11 mock treatment 0.22 -0.00248 -0.34 0.227 0.00249 0.36 0.012 0.0242 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J12 mock treatment 0.223 5.2E-4 0.07 0.226 0.00149 0.22 0.2029 0.8947 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J13 mock treatment 0.221 -0.00148 -0.2 0.228 0.00349 0.5 0.2118 0.3895 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J14 mock treatment 0.218 -0.00448 -0.62 0.226 0.00149 0.22 -0.2855 -0.4357 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J15 mock treatment 0.219 -0.00348 -0.48 0.222 -0.00251 -0.36 -0.5964 -0.9903 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J16 mock treatment 0.223 5.2E-4 0.07 0.223 -0.00151 -0.22 -0.1035 -0.4504 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J17 mock treatment 0.225 0.00252 0.35 0.226 0.00149 0.22 0.3983 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J18 mock treatment 0.224 0.00152 0.21 0.226 0.00149 0.22 0.3006 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J19 mock treatment 0.228 0.00552 0.76 0.233 0.00849 1.23 1.4063 0.9739 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J20 mock treatment 0.227 0.00452 0.62 0.228 0.00349 0.5 0.798 0.9944 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J21 mock treatment 0.226 0.00352 0.49 0.225 4.89E-4 0.07 0.3939 0.8015 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J22 mock treatment 0.223 5.2E-4 0.07 0.22 -0.00451 -0.65 -0.4099 -0.6253 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J23 mock treatment 0.227 0.00452 0.62 0.225 4.89E-4 0.07 0.4915 0.7821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base J24 mock treatment 0.234 0.0115 1.59 0.228 0.00349 0.5 1.4818 0.8876 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K01 mock treatment 0.23 0.00752 1.04 0.234 0.00949 1.37 1.7039 0.9907 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K02 mock treatment 0.229 0.00652 0.9 0.226 0.00149 0.22 0.7891 0.852 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K03 mock treatment 0.226 0.00352 0.49 0.226 0.00149 0.22 0.496 0.9327 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K04 mock treatment 0.223 5.2E-4 0.07 0.228 0.00349 0.5 0.4072 0.7998 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K05 mock treatment 0.223 5.2E-4 0.07 0.227 0.00249 0.36 0.3051 0.832 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K06 mock treatment 0.225 0.00252 0.35 0.227 0.00249 0.36 0.5004 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K07 mock treatment 0.219 -0.00348 -0.48 0.229 0.00449 0.65 0.1186 0.1469 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K08 mock treatment 0.225 0.00252 0.35 0.229 0.00449 0.65 0.7047 0.9575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K09 mock treatment 0.218 -0.00448 -0.62 0.221 -0.00351 -0.51 -0.7962 -0.9951 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K10 mock treatment 0.219 -0.00348 -0.48 0.225 4.89E-4 0.07 -0.29 -0.5967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K11 mock treatment 0.219 -0.00348 -0.48 0.225 4.89E-4 0.07 -0.29 -0.5967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K12 mock treatment 0.221 -0.00148 -0.2 0.228 0.00349 0.5 0.2118 0.3895 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K13 mock treatment 0.22 -0.00248 -0.34 0.227 0.00249 0.36 0.012 0.0242 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K14 mock treatment 0.22 -0.00248 -0.34 0.222 -0.00251 -0.36 -0.4987 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K15 mock treatment 0.22 -0.00248 -0.34 0.224 -5.11E-4 -0.07 -0.2944 -0.8401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K16 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K17 mock treatment 0.222 -4.8E-4 -0.07 0.227 0.00249 0.36 0.2074 0.5672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K18 mock treatment 0.226 0.00352 0.49 0.224 -5.11E-4 -0.07 0.2917 0.5931 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K19 mock treatment 0.224 0.00152 0.21 0.226 0.00149 0.22 0.3006 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K20 mock treatment 0.221 -0.00148 -0.2 0.223 -0.00151 -0.22 -0.2989 -0.9995 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K21 mock treatment 0.22 -0.00248 -0.34 0.222 -0.00251 -0.36 -0.4987 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K22 mock treatment 0.222 -4.8E-4 -0.07 0.225 4.89E-4 0.07 0.0031 0.0321 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K23 mock treatment 0.224 0.00152 0.21 0.226 0.00149 0.22 0.3006 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base K24 mock treatment 0.229 0.00652 0.9 0.229 0.00449 0.65 1.0955 0.987 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L01 mock treatment 0.218 -0.00448 -0.62 0.232 0.00749 1.08 0.3273 0.2626 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L02 mock treatment 0.225 0.00252 0.35 0.226 0.00149 0.22 0.3983 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L03 mock treatment 0.222 -4.8E-4 -0.07 0.222 -0.00251 -0.36 -0.3033 -0.8227 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L04 mock treatment 0.221 -0.00148 -0.2 0.224 -5.11E-4 -0.07 -0.1967 -0.9051 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L05 mock treatment 0.223 5.2E-4 0.07 0.227 0.00249 0.36 0.3051 0.832 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L06 mock treatment 0.228 0.00552 0.76 0.224 -5.11E-4 -0.07 0.4871 0.6357 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L07 mock treatment 0.221 -0.00148 -0.2 0.226 0.00149 0.22 0.0076 0.0255 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L08 mock treatment 0.225 0.00252 0.35 0.224 -5.11E-4 -0.07 0.194 0.5452 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L09 mock treatment 0.224 0.00152 0.21 0.224 -5.11E-4 -0.07 0.0963 0.4328 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L10 mock treatment 0.213 -0.00948 -1.31 0.221 -0.00351 -0.51 -1.2846 -0.9147 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L11 mock treatment 0.216 -0.00648 -0.9 0.221 -0.00351 -0.51 -0.9916 -0.9638 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L12 mock treatment 0.218 -0.00448 -0.62 0.223 -0.00151 -0.22 -0.5919 -0.902 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L13 mock treatment 0.222 -4.8E-4 -0.07 0.227 0.00249 0.36 0.2074 0.5672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L14 mock treatment 0.214 -0.00848 -1.17 0.22 -0.00451 -0.65 -1.2891 -0.9617 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L15 mock treatment 0.218 -0.00448 -0.62 0.222 -0.00251 -0.36 -0.6941 -0.9676 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L16 mock treatment 0.22 -0.00248 -0.34 0.228 0.00349 0.5 0.1141 0.1873 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L17 mock treatment 0.224 0.00152 0.21 0.229 0.00449 0.65 0.607 0.8906 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L18 mock treatment 0.219 -0.00348 -0.48 0.227 0.00249 0.36 -0.0857 -0.1427 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L19 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L20 mock treatment 0.223 5.2E-4 0.07 0.221 -0.00351 -0.51 -0.3078 -0.6009 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L21 mock treatment 0.217 -0.00548 -0.76 0.22 -0.00451 -0.65 -0.996 -0.9972 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L22 mock treatment 0.22 -0.00248 -0.34 0.221 -0.00351 -0.51 -0.6008 -0.9818 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L23 mock treatment 0.227 0.00452 0.62 0.227 0.00249 0.36 0.6958 0.9656 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base L24 mock treatment 0.229 0.00652 0.9 0.224 -5.11E-4 -0.07 0.5848 0.647 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M01 mock treatment 0.227 0.00452 0.62 0.231 0.00649 0.94 1.1044 0.9805 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M02 mock treatment 0.225 0.00252 0.35 0.23 0.00549 0.79 0.8069 0.9317 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M03 mock treatment 0.22 -0.00248 -0.34 0.227 0.00249 0.36 0.012 0.0242 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M04 mock treatment 0.224 0.00152 0.21 0.227 0.00249 0.36 0.4028 0.9672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M05 mock treatment 0.226 0.00352 0.49 0.226 0.00149 0.22 0.496 0.9327 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M06 mock treatment 0.228 0.00552 0.76 0.227 0.00249 0.36 0.7935 0.9411 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M07 mock treatment 0.221 -0.00148 -0.2 0.23 0.00549 0.79 0.4161 0.5082 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M08 mock treatment 0.224 0.00152 0.21 0.232 0.00749 1.08 0.9135 0.8289 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M09 mock treatment 0.223 5.2E-4 0.07 0.226 0.00149 0.22 0.2029 0.8947 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M10 mock treatment 0.218 -0.00448 -0.62 0.223 -0.00151 -0.22 -0.5919 -0.902 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M11 mock treatment 0.221 -0.00148 -0.2 0.223 -0.00151 -0.22 -0.2989 -0.9995 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M12 mock treatment 0.221 -0.00148 -0.2 0.221 -0.00351 -0.51 -0.5031 -0.9202 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M13 mock treatment 0.22 -0.00248 -0.34 0.228 0.00349 0.5 0.1141 0.1873 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M14 mock treatment 0.218 -0.00448 -0.62 0.226 0.00149 0.22 -0.2855 -0.4357 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M15 mock treatment 0.221 -0.00148 -0.2 0.221 -0.00351 -0.51 -0.5031 -0.9202 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M16 mock treatment 0.222 -4.8E-4 -0.07 0.226 0.00149 0.22 0.1052 0.4675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M17 mock treatment 0.224 0.00152 0.21 0.229 0.00449 0.65 0.607 0.8906 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M18 mock treatment 0.222 -4.8E-4 -0.07 0.23 0.00549 0.79 0.5138 0.6457 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M19 mock treatment 0.226 0.00352 0.49 0.23 0.00549 0.79 0.9046 0.9725 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M20 mock treatment 0.223 5.2E-4 0.07 0.225 4.89E-4 0.07 0.1008 1.0 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M21 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M22 mock treatment 0.223 5.2E-4 0.07 0.226 0.00149 0.22 0.2029 0.8947 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M23 mock treatment 0.225 0.00252 0.35 0.226 0.00149 0.22 0.3983 0.9732 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base M24 mock treatment 0.226 0.00352 0.49 0.225 4.89E-4 0.07 0.3939 0.8015 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N01 mock treatment 0.221 -0.00148 -0.2 0.229 0.00449 0.65 0.314 0.4618 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N02 mock treatment 0.224 0.00152 0.21 0.219 -0.00551 -0.8 -0.4143 -0.5033 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N03 mock treatment 0.224 0.00152 0.21 0.226 0.00149 0.22 0.3006 0.9999 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N04 mock treatment 0.219 -0.00348 -0.48 0.224 -5.11E-4 -0.07 -0.3921 -0.8062 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N05 mock treatment 0.222 -4.8E-4 -0.07 0.226 0.00149 0.22 0.1052 0.4675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N06 mock treatment 0.222 -4.8E-4 -0.07 0.228 0.00349 0.5 0.3095 0.6089 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N07 mock treatment 0.22 -0.00248 -0.34 0.227 0.00249 0.36 0.012 0.0242 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N08 mock treatment 0.215 -0.00748 -1.03 0.233 0.00849 1.23 0.1364 0.0851 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N09 mock treatment 0.212 -0.0105 -1.45 0.217 -0.00751 -1.08 -1.7909 -0.9899 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N10 mock treatment 0.219 -0.00348 -0.48 0.222 -0.00251 -0.36 -0.5964 -0.9903 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N11 mock treatment 0.216 -0.00648 -0.9 0.216 -0.00851 -1.23 -1.5023 -0.9879 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N12 mock treatment 0.217 -0.00548 -0.76 0.221 -0.00351 -0.51 -0.8939 -0.981 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N13 mock treatment 0.222 -4.8E-4 -0.07 0.226 0.00149 0.22 0.1052 0.4675 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N14 mock treatment 0.215 -0.00748 -1.03 0.221 -0.00351 -0.51 -1.0893 -0.9463 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N15 mock treatment 0.215 -0.00748 -1.03 0.223 -0.00151 -0.22 -0.885 -0.8379 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N16 mock treatment 0.219 -0.00348 -0.48 0.229 0.00449 0.65 0.1186 0.1469 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N17 mock treatment 0.22 -0.00248 -0.34 0.221 -0.00351 -0.51 -0.6008 -0.9818 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N18 mock treatment 0.221 -0.00148 -0.2 0.227 0.00249 0.36 0.1097 0.2652 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N19 mock treatment 0.219 -0.00348 -0.48 0.227 0.00249 0.36 -0.0857 -0.1427 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N20 mock treatment 0.219 -0.00348 -0.48 0.226 0.00149 0.22 -0.1878 -0.3566 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N21 mock treatment 0.22 -0.00248 -0.34 0.224 -5.11E-4 -0.07 -0.2944 -0.8401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N22 mock treatment 0.219 -0.00348 -0.48 0.225 4.89E-4 0.07 -0.29 -0.5967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N23 mock treatment 0.225 0.00252 0.35 0.224 -5.11E-4 -0.07 0.194 0.5452 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base N24 mock treatment 0.227 0.00452 0.62 0.227 0.00249 0.36 0.6958 0.9656 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O01 mock treatment 0.217 -0.00548 -0.76 0.228 0.00349 0.5 -0.1789 -0.1967 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O02 mock treatment 0.226 0.00352 0.49 0.224 -5.11E-4 -0.07 0.2917 0.5931 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O03 mock treatment 0.22 -0.00248 -0.34 0.22 -0.00451 -0.65 -0.703 -0.9549 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O04 mock treatment 0.222 -4.8E-4 -0.07 0.221 -0.00351 -0.51 -0.4054 -0.7928 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O05 mock treatment 0.222 -4.8E-4 -0.07 0.224 -5.11E-4 -0.07 -0.099 -0.9986 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O06 mock treatment 0.222 -4.8E-4 -0.07 0.223 -0.00151 -0.22 -0.2012 -0.8821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O07 mock treatment 0.22 -0.00248 -0.34 0.224 -5.11E-4 -0.07 -0.2944 -0.8401 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O08 mock treatment 0.225 0.00252 0.35 0.225 4.89E-4 0.07 0.2962 0.8336 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O09 mock treatment 0.22 -0.00248 -0.34 0.222 -0.00251 -0.36 -0.4987 -0.9996 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O10 mock treatment 0.219 -0.00348 -0.48 0.217 -0.00751 -1.08 -1.1071 -0.9329 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O11 mock treatment 0.22 -0.00248 -0.34 0.218 -0.00651 -0.94 -0.9072 -0.9064 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O12 mock treatment 0.222 -4.8E-4 -0.07 0.217 -0.00751 -1.08 -0.814 -0.7489 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O13 mock treatment 0.217 -0.00548 -0.76 0.23 0.00549 0.79 0.0254 0.0231 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O14 mock treatment 0.217 -0.00548 -0.76 0.224 -5.11E-4 -0.07 -0.5875 -0.7724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O15 mock treatment 0.224 0.00152 0.21 0.219 -0.00551 -0.8 -0.4143 -0.5033 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O16 mock treatment 0.219 -0.00348 -0.48 0.226 0.00149 0.22 -0.1878 -0.3566 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O17 mock treatment 0.222 -4.8E-4 -0.07 0.223 -0.00151 -0.22 -0.2012 -0.8821 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O18 mock treatment 0.222 -4.8E-4 -0.07 0.225 4.89E-4 0.07 0.0031 0.0321 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O19 mock treatment 0.217 -0.00548 -0.76 0.224 -5.11E-4 -0.07 -0.5875 -0.7724 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O20 mock treatment 0.219 -0.00348 -0.48 0.224 -5.11E-4 -0.07 -0.3921 -0.8062 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O21 mock treatment 0.221 -0.00148 -0.2 0.222 -0.00251 -0.36 -0.401 -0.9632 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O22 mock treatment 0.221 -0.00148 -0.2 0.224 -5.11E-4 -0.07 -0.1967 -0.9051 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O23 mock treatment 0.223 5.2E-4 0.07 0.221 -0.00351 -0.51 -0.3078 -0.6009 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base O24 mock treatment 0.222 -4.8E-4 -0.07 0.219 -0.00551 -0.8 -0.6097 -0.7633 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P01 mock treatment 0.219 -0.00348 -0.48 0.23 0.00549 0.79 0.2207 0.2381 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P02 mock treatment 0.227 0.00452 0.62 0.223 -0.00151 -0.22 0.2873 0.4343 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P03 mock treatment 0.22 -0.00248 -0.34 0.226 0.00149 0.22 -0.0901 -0.2228 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P04 mock treatment 0.221 -0.00148 -0.2 0.22 -0.00451 -0.65 -0.6053 -0.8864 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P05 mock treatment 0.223 5.2E-4 0.07 0.223 -0.00151 -0.22 -0.1035 -0.4504 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P06 mock treatment 0.224 0.00152 0.21 0.228 0.00349 0.5 0.5049 0.9247 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P07 mock treatment 0.22 -0.00248 -0.34 0.226 0.00149 0.22 -0.0901 -0.2228 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P08 mock treatment 0.222 -4.8E-4 -0.07 0.227 0.00249 0.36 0.2074 0.5672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P09 mock treatment 0.223 5.2E-4 0.07 0.222 -0.00251 -0.36 -0.2056 -0.5562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P10 mock treatment 0.224 0.00152 0.21 0.22 -0.00451 -0.65 -0.3122 -0.4561 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P11 mock treatment 0.218 -0.00448 -0.62 0.22 -0.00451 -0.65 -0.8983 -0.9997 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P12 mock treatment 0.218 -0.00448 -0.62 0.223 -0.00151 -0.22 -0.5919 -0.902 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P13 mock treatment 0.223 5.2E-4 0.07 0.222 -0.00251 -0.36 -0.2056 -0.5562 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P14 mock treatment 0.219 -0.00348 -0.48 0.224 -5.11E-4 -0.07 -0.3921 -0.8062 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P15 mock treatment 0.216 -0.00648 -0.9 0.223 -0.00151 -0.22 -0.7873 -0.8545 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P16 mock treatment 0.222 -4.8E-4 -0.07 0.229 0.00449 0.65 0.4117 0.6315 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P17 mock treatment 0.222 -4.8E-4 -0.07 0.219 -0.00551 -0.8 -0.6097 -0.7633 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P18 mock treatment 0.218 -0.00448 -0.62 0.228 0.00349 0.5 -0.0812 -0.1018 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P19 mock treatment 0.222 -4.8E-4 -0.07 0.227 0.00249 0.36 0.2074 0.5672 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P20 mock treatment 0.218 -0.00448 -0.62 0.226 0.00149 0.22 -0.2855 -0.4357 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P21 mock treatment 0.22 -0.00248 -0.34 0.225 4.89E-4 0.07 -0.1923 -0.5497 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P22 mock treatment 0.221 -0.00148 -0.2 0.219 -0.00551 -0.8 -0.7074 -0.8608 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P23 mock treatment 0.224 0.00152 0.21 0.222 -0.00251 -0.36 -0.1079 -0.2575 1017.0003 EnzCoupledColor(1017.0003) TrypanothioneReductase 1017.0003.Base P24 mock treatment 0.232 0.00952 1.32 0.221 -0.00351 -0.51 0.5714 0.4054