ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A01 mock treatment 88800.0 -6360.0 -0.59 84800.0 -8960.0 -0.83 -1.0013 -0.9853 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A02 mock treatment 89200.0 -5960.0 -0.55 90800.0 -2960.0 -0.27 -0.582 -0.9489 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A03 compound treatment 94400.0 -763.0 -0.07 88800.0 -4960.0 -0.46 -0.3748 -0.8056 3000673 BCB01_000001 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A04 compound treatment 87600.0 -7560.0 -0.7 86800.0 -6960.0 -0.65 -0.9482 -0.9993 3000674 BCB01_000002 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A05 compound treatment 75200.0 -20000.0 -1.84 78400.0 -15400.0 -1.42 -2.3053 -0.9921 3000675 BCB01_000003 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A06 compound treatment 77600.0 -17600.0 -1.62 84400.0 -9360.0 -0.87 -1.7559 -0.9575 3000676 BCB01_000004 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A07 compound treatment 80800.0 -14400.0 -1.32 84400.0 -9360.0 -0.87 -1.5478 -0.9792 3093034 BCB01_000005 COc1cc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A08 compound treatment 82400.0 -12800.0 -1.17 74000.0 -19800.0 -1.83 -2.1254 -0.9769 3000677 BCB01_000006 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A09 compound treatment 86800.0 -8360.0 -0.77 78400.0 -15400.0 -1.42 -1.5508 -0.9582 3093035 BCB01_000007 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A10 compound treatment 86000.0 -9160.0 -0.84 84800.0 -8960.0 -0.83 -1.1834 -1.0 3000678 BCB01_000008 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A11 compound treatment 81600.0 -13600.0 -1.25 75200.0 -18600.0 -1.72 -2.0988 -0.9875 3093104 BCB01_000009 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A12 compound treatment 68800.0 -26400.0 -2.42 68000.0 -25800.0 -2.39 -3.4032 -1.0 3093105 BCB01_000010 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A13 compound treatment 87200.0 -7960.0 -0.73 92400.0 -1360.0 -0.13 -0.6072 -0.817 3000679 BCB01_000011 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A14 compound treatment 74400.0 -20800.0 -1.91 76400.0 -17400.0 -1.61 -2.4884 -0.9964 3093106 BCB01_000012 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A15 compound treatment 59600.0 -35600.0 -3.27 56400.0 -37400.0 -3.46 -4.7619 -0.9996 3093107 BCB01_000013 CCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A16 compound treatment 74000.0 -21200.0 -1.95 77200.0 -16600.0 -1.54 -2.462 -0.9931 3000680 BCB01_000014 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A17 compound treatment 83200.0 -12000.0 -1.1 85200.0 -8560.0 -0.79 -1.3393 -0.9871 3093108 BCB01_000015 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A18 compound treatment 87200.0 -7960.0 -0.73 89200.0 -4560.0 -0.42 -0.8169 -0.9659 3093109 BCB01_000016 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A19 compound treatment 93200.0 -1960.0 -0.18 83200.0 -10600.0 -0.98 -0.8199 -0.8236 3000681 BCB01_000017 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A20 compound treatment 88400.0 -6760.0 -0.62 89200.0 -4560.0 -0.42 -0.7389 -0.9823 3093110 BCB01_000018 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A21 compound treatment 90800.0 -4360.0 -0.4 91600.0 -2160.0 -0.2 -0.4255 -0.9486 3000682 BCB01_000019 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A22 compound treatment 80400.0 -14800.0 -1.36 87600.0 -6160.0 -0.57 -1.3641 -0.926 3093111 BCB01_000020 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A23 mock treatment 97600.0 2440.0 0.22 92400.0 -1360.0 -0.13 0.0692 0.2691 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 A24 mock treatment 101600.0 6440.0 0.59 92400.0 -1360.0 -0.13 0.3294 0.5441 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B01 mock treatment 100000.0 4840.0 0.44 90800.0 -2960.0 -0.27 0.1205 0.2304 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B02 mock treatment 96800.0 1640.0 0.15 106400.0 12600.0 1.17 0.9348 0.7915 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B03 compound treatment 109200.0 14000.0 1.29 104400.0 10600.0 0.99 1.6102 0.9911 3093112 BCB01_000021 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B04 compound treatment 97600.0 2440.0 0.22 96000.0 2240.0 0.21 0.3052 0.9992 3000683 BCB01_000022 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B05 compound treatment 92000.0 -3160.0 -0.29 88800.0 -4960.0 -0.46 -0.5309 -0.9756 3093113 BCB01_000023 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B06 compound treatment 85200.0 -9960.0 -0.92 73200.0 -20600.0 -1.91 -1.9957 -0.9437 3093114 BCB01_000024 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B07 compound treatment 56000.0 -39200.0 -3.6 52800.0 -41000.0 -3.8 -5.232 -0.9997 3000684 BCB01_000025 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B08 compound treatment 85600.0 -9560.0 -0.88 88000.0 -5760.0 -0.53 -0.9997 -0.9714 3093115 BCB01_000026 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B09 compound treatment 95600.0 438.0 0.04 89600.0 -4160.0 -0.39 -0.2444 -0.6299 3093116 BCB01_000027 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B10 compound treatment 92800.0 -2360.0 -0.22 92000.0 -1760.0 -0.16 -0.2692 -0.9901 3000685 BCB01_000028 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B11 compound treatment 81200.0 -14000.0 -1.28 88400.0 -5360.0 -0.5 -1.2596 -0.9147 3093117 BCB01_000029 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(C)cc(C)cc4C)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B12 compound treatment 80800.0 -14400.0 -1.32 66800.0 -27000.0 -2.5 -2.7013 -0.9556 3093118 BCB01_000030 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B13 compound treatment 86800.0 -8360.0 -0.77 82400.0 -11400.0 -1.05 -1.2886 -0.9881 3000686 BCB01_000031 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4C)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B14 compound treatment 81600.0 -13600.0 -1.25 81200.0 -12600.0 -1.16 -1.7055 -0.9994 3093119 BCB01_000032 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B15 compound treatment 86800.0 -8360.0 -0.77 84000.0 -9760.0 -0.9 -1.1838 -0.9967 3093120 BCB01_000033 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(c4ccccc4)c5ccccc5)C(=O)N(C3=O)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B16 compound treatment 76400.0 -18800.0 -1.73 65200.0 -28600.0 -2.65 -3.0924 -0.9785 3000687 BCB01_000034 CCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B17 compound treatment 85200.0 -9960.0 -0.92 83600.0 -10200.0 -0.94 -1.3141 -0.9999 3000688 BCB01_000035 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B18 compound treatment 76000.0 -19200.0 -1.76 77600.0 -16200.0 -1.5 -2.3057 -0.9967 3093121 BCB01_000036 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B19 compound treatment 82000.0 -13200.0 -1.21 83600.0 -10200.0 -0.94 -1.5222 -0.9923 3093122 BCB01_000037 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B20 compound treatment 83600.0 -11600.0 -1.06 81200.0 -12600.0 -1.16 -1.5754 -0.999 3093123 BCB01_000038 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B21 compound treatment 98000.0 2840.0 0.26 100800.0 7040.0 0.65 0.6458 0.9192 3000689 BCB01_000039 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B22 compound treatment 80000.0 -15200.0 -1.39 76800.0 -17000.0 -1.57 -2.098 -0.9982 3093124 BCB01_000040 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B23 mock treatment 102400.0 7240.0 0.67 96000.0 2240.0 0.21 0.6174 0.8854 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 B24 mock treatment 97600.0 2440.0 0.22 100400.0 6640.0 0.62 0.5936 0.9065 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C01 mock treatment 92400.0 -2760.0 -0.25 90800.0 -2960.0 -0.27 -0.3738 -0.9992 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C02 mock treatment 90800.0 -4360.0 -0.4 88000.0 -5760.0 -0.53 -0.6614 -0.9901 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C03 compound treatment 87200.0 -7960.0 -0.73 78800.0 -15000.0 -1.39 -1.4986 -0.9555 3000690 BCB01_000041 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C04 compound treatment 83200.0 -12000.0 -1.1 78400.0 -15400.0 -1.42 -1.785 -0.9919 3093125 BCB01_000042 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C05 compound treatment 81200.0 -14000.0 -1.28 79600.0 -14200.0 -1.31 -1.8364 -0.9999 3093282 BCB01_000043 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C06 compound treatment 86800.0 -8360.0 -0.77 82000.0 -11800.0 -1.09 -1.3149 -0.9854 3000691 BCB01_000044 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C07 compound treatment 83600.0 -11600.0 -1.06 84000.0 -9760.0 -0.9 -1.3919 -0.9968 3093194 BCB01_000045 COc1cc(NN2C3C(C=CC2C(O)C4CCC(CC4)C(=C)C)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C08 compound treatment 78400.0 -16800.0 -1.54 75200.0 -18600.0 -1.72 -2.3069 -0.9985 3093195 BCB01_000046 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C09 compound treatment 84800.0 -10400.0 -0.95 82000.0 -11800.0 -1.09 -1.4449 -0.9978 3000692 BCB01_000047 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C)C3=O)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C10 compound treatment 80800.0 -14400.0 -1.32 75200.0 -18600.0 -1.72 -2.1508 -0.9915 3093196 BCB01_000048 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C11 compound treatment 54400.0 -40800.0 -3.75 45200.0 -48600.0 -4.5 -5.8342 -0.9959 3093197 BCB01_000049 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C12 compound treatment 79200.0 -16000.0 -1.47 78400.0 -15400.0 -1.42 -2.0451 -0.9999 3000693 BCB01_000050 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C13 compound treatment 85600.0 -9560.0 -0.88 81200.0 -12600.0 -1.16 -1.4453 -0.9904 3093198 BCB01_000051 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C14 compound treatment 92400.0 -2760.0 -0.25 80400.0 -13400.0 -1.24 -1.0555 -0.8348 3000694 BCB01_000052 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C15 compound treatment 80000.0 -15200.0 -1.39 75200.0 -18600.0 -1.72 -2.2028 -0.9946 3093199 BCB01_000053 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C16 compound treatment 84000.0 -11200.0 -1.03 72400.0 -21400.0 -1.98 -2.1262 -0.9532 3093200 BCB01_000054 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C17 compound treatment 77200.0 -18000.0 -1.65 78000.0 -15800.0 -1.46 -2.2014 -0.9981 3000695 BCB01_000055 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C18 compound treatment 84800.0 -10400.0 -0.95 88000.0 -5760.0 -0.53 -1.0517 -0.9625 3093201 BCB01_000056 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C19 compound treatment 72800.0 -22400.0 -2.06 67600.0 -26200.0 -2.43 -3.1693 -0.9966 3093202 BCB01_000057 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C20 compound treatment 97600.0 2440.0 0.22 87600.0 -6160.0 -0.57 -0.2454 -0.3999 3000696 BCB01_000058 COc1ccc(cc1)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C21 compound treatment 80000.0 -15200.0 -1.39 84800.0 -8960.0 -0.83 -1.5736 -0.9694 3093203 BCB01_000059 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C22 compound treatment 101600.0 6440.0 0.59 93600.0 -163.0 -0.02 0.4081 0.6889 3093204 BCB01_000060 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C23 mock treatment 90000.0 -5160.0 -0.47 92800.0 -963.0 -0.09 -0.3989 -0.8255 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 C24 mock treatment 94800.0 -363.0 -0.03 97600.0 3840.0 0.36 0.2279 0.638 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D01 mock treatment 100800.0 5640.0 0.52 90000.0 -3760.0 -0.35 0.1201 0.1921 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D02 mock treatment 97600.0 2440.0 0.22 96400.0 2640.0 0.24 0.3314 0.9991 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D03 compound treatment 89600.0 -5560.0 -0.51 85600.0 -8160.0 -0.76 -0.8968 -0.9819 3000697 BCB01_000061 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccc(O)c4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D04 compound treatment 89200.0 -5960.0 -0.55 70800.0 -23000.0 -2.13 -1.8928 -0.8612 3093205 BCB01_000062 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D05 compound treatment 98000.0 2840.0 0.26 91600.0 -2160.0 -0.2 0.0428 0.1301 3093206 BCB01_000063 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)B(O)O)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D06 compound treatment 86800.0 -8360.0 -0.77 85600.0 -8160.0 -0.76 -1.0789 -1.0 3000698 BCB01_000064 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D07 compound treatment 81600.0 -13600.0 -1.25 81200.0 -12600.0 -1.16 -1.7055 -0.9994 3093207 BCB01_000065 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cn(C(=O)C)c5ccccc45)C(=O)N(C3=O)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D08 compound treatment 79200.0 -16000.0 -1.47 87200.0 -6560.0 -0.61 -1.4684 -0.9239 3000792 BCB01_000066 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D09 compound treatment 81600.0 -13600.0 -1.25 87200.0 -6560.0 -0.61 -1.3123 -0.9455 3000794 BCB01_000067 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(C)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D10 compound treatment 78800.0 -16400.0 -1.51 78800.0 -15000.0 -1.39 -2.0449 -0.9992 3000796 BCB01_000068 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D11 compound treatment 80000.0 -15200.0 -1.39 86000.0 -7760.0 -0.72 -1.495 -0.9526 3000797 BCB01_000069 CC(C)c1ccc(NN2C3C(C=CC2C(O)CC(C)c4ccc(C)o4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D12 compound treatment 78400.0 -16800.0 -1.54 77200.0 -16600.0 -1.54 -2.1758 -1.0 3093208 BCB01_000070 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4c(F)cccc4Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D13 compound treatment 82400.0 -12800.0 -1.17 74400.0 -19400.0 -1.79 -2.0992 -0.9788 3093209 BCB01_000071 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccs4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D14 compound treatment 80800.0 -14400.0 -1.32 70400.0 -23400.0 -2.17 -2.4654 -0.9719 3000798 BCB01_000072 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D15 compound treatment 80800.0 -14400.0 -1.32 74400.0 -19400.0 -1.79 -2.2032 -0.9886 3093210 BCB01_000073 CC(C)c1ccc(NN2C3C(C=CC2C(O)Cc4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D16 compound treatment 79200.0 -16000.0 -1.47 77600.0 -16200.0 -1.5 -2.0976 -0.9999 3000800 BCB01_000074 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D17 compound treatment 78400.0 -16800.0 -1.54 76400.0 -17400.0 -1.61 -2.2282 -0.9998 3093211 BCB01_000075 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D18 compound treatment 84400.0 -10800.0 -0.99 84000.0 -9760.0 -0.9 -1.3399 -0.999 3000876 BCB01_000076 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D19 compound treatment 98800.0 3640.0 0.33 99200.0 5440.0 0.5 0.593 0.9802 3000877 BCB01_000077 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc5OCOc5c4)C(=O)N(C3=O)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D20 compound treatment 72000.0 -23200.0 -2.13 83600.0 -10200.0 -0.94 -2.1726 -0.9326 3000878 BCB01_000078 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D21 compound treatment 90400.0 -4760.0 -0.44 80000.0 -13800.0 -1.28 -1.2118 -0.8984 3000880 BCB01_000079 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4=C[C@H]5C[C@@H](C4)C5(C)C)C(=O)N(C3=O)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D22 compound treatment 78800.0 -16400.0 -1.51 72800.0 -21000.0 -1.94 -2.4382 -0.992 3093212 BCB01_000080 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D23 mock treatment 93200.0 -1960.0 -0.18 92800.0 -963.0 -0.09 -0.1907 -0.9472 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 D24 mock treatment 92800.0 -2360.0 -0.22 94000.0 238.0 0.02 -0.1381 -0.6322 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E01 mock treatment 94000.0 -1160.0 -0.11 88000.0 -5760.0 -0.53 -0.4533 -0.8322 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E02 mock treatment 93200.0 -1960.0 -0.18 87600.0 -6160.0 -0.57 -0.5315 -0.8873 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E03 compound treatment 95200.0 37.5 0.0 91200.0 -2560.0 -0.24 -0.1655 -0.6968 3000882 BCB01_000081 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E04 compound treatment 92800.0 -2360.0 -0.22 85600.0 -8160.0 -0.76 -0.6886 -0.8748 3093213 BCB01_000082 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E05 compound treatment 84000.0 -11200.0 -1.03 88800.0 -4960.0 -0.46 -1.0513 -0.9344 3093214 BCB01_000083 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E06 compound treatment 83600.0 -11600.0 -1.06 74800.0 -19000.0 -1.76 -1.9949 -0.971 3000884 BCB01_000084 CN1C(=O)C2C=CC(C(O)C3CCC(CC3)C(=C)C)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E07 compound treatment 77200.0 -18000.0 -1.65 82400.0 -11400.0 -1.05 -1.913 -0.9764 3093215 BCB01_000085 CN1C(=O)C2C=CC(C(O)c3ccco3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E08 compound treatment 80400.0 -14800.0 -1.36 79200.0 -14600.0 -1.35 -1.9146 -1.0 3093216 BCB01_000086 CCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E09 compound treatment 82800.0 -12400.0 -1.14 78400.0 -15400.0 -1.42 -1.811 -0.9938 3000885 BCB01_000087 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E10 compound treatment 71200.0 -24000.0 -2.2 69600.0 -24200.0 -2.24 -3.1422 -1.0 3093283 BCB01_000088 CCCCCCCCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E11 compound treatment 74800.0 -20400.0 -1.87 70000.0 -23800.0 -2.2 -2.8819 -0.9967 3093284 BCB01_000089 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E12 compound treatment 84400.0 -10800.0 -0.99 77600.0 -16200.0 -1.5 -1.7593 -0.9798 3000886 BCB01_000090 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E13 compound treatment 86400.0 -8760.0 -0.81 79600.0 -14200.0 -1.31 -1.4982 -0.9726 3093285 BCB01_000091 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E14 compound treatment 80000.0 -15200.0 -1.39 79200.0 -14600.0 -1.35 -1.9407 -0.9999 3093286 BCB01_000092 COc1ccc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c5ccccc15 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E15 compound treatment 78000.0 -17200.0 -1.58 79200.0 -14600.0 -1.35 -2.0707 -0.997 3000889 BCB01_000093 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E16 compound treatment 83600.0 -11600.0 -1.06 85200.0 -8560.0 -0.79 -1.3133 -0.9896 3093287 BCB01_000094 COc1cc(Br)cc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E17 compound treatment 79200.0 -16000.0 -1.47 77200.0 -16600.0 -1.54 -2.1238 -0.9998 3093288 BCB01_000095 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E18 compound treatment 74400.0 -20800.0 -1.91 69600.0 -24200.0 -2.24 -2.9341 -0.9969 3000890 BCB01_000096 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3N5CCCCC5)C(=O)N(C)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E19 compound treatment 81600.0 -13600.0 -1.25 90400.0 -3360.0 -0.31 -1.1025 -0.8574 3093289 BCB01_000097 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E20 compound treatment 80000.0 -15200.0 -1.39 80000.0 -13800.0 -1.28 -1.8882 -0.999 3093290 BCB01_000098 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E21 compound treatment 83200.0 -12000.0 -1.1 83600.0 -10200.0 -0.94 -1.4441 -0.997 3000891 BCB01_000099 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E22 compound treatment 79600.0 -15600.0 -1.43 72400.0 -21400.0 -1.98 -2.4124 -0.9873 3093291 BCB01_000100 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E23 mock treatment 96400.0 1240.0 0.11 97600.0 3840.0 0.36 0.332 0.889 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 E24 mock treatment 97200.0 2040.0 0.19 98400.0 4640.0 0.43 0.4365 0.9308 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F01 mock treatment 84000.0 -11200.0 -1.03 87600.0 -6160.0 -0.57 -1.1299 -0.9617 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F02 mock treatment 81200.0 -14000.0 -1.28 87200.0 -6560.0 -0.61 -1.3383 -0.9417 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F03 compound treatment 81600.0 -13600.0 -1.25 78000.0 -15800.0 -1.46 -1.9152 -0.9969 3093292 BCB01_000101 CC(C)c1ccc(NN2C3C(C=CC2C(O)/C=C(\C)/CCC=C(C)C)C(=O)N(C3=O)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F04 compound treatment 71600.0 -23600.0 -2.17 71600.0 -22200.0 -2.05 -2.9851 -0.9996 3000892 BCB01_000102 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F05 compound treatment 81200.0 -14000.0 -1.28 83200.0 -10600.0 -0.98 -1.6004 -0.991 3093293 BCB01_000103 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F06 compound treatment 73600.0 -21600.0 -1.98 65200.0 -28600.0 -2.65 -3.2745 -0.9899 3000894 BCB01_000104 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F07 compound treatment 75200.0 -20000.0 -1.84 68800.0 -25000.0 -2.31 -2.9345 -0.9934 3093294 BCB01_000105 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F08 compound treatment 79200.0 -16000.0 -1.47 73600.0 -20200.0 -1.87 -2.3597 -0.9929 3093295 BCB01_000106 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F09 compound treatment 74000.0 -21200.0 -1.95 76400.0 -17400.0 -1.61 -2.5144 -0.9955 3000896 BCB01_000107 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F10 compound treatment 73600.0 -21600.0 -1.98 70400.0 -23400.0 -2.17 -2.9337 -0.999 3093296 BCB01_000108 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F11 compound treatment 81600.0 -13600.0 -1.25 79200.0 -14600.0 -1.35 -1.8366 -0.9992 3093297 BCB01_000109 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)C(=O)C)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F12 compound treatment 74400.0 -20800.0 -1.91 74000.0 -19800.0 -1.83 -2.6457 -0.9998 3000898 BCB01_000110 CC(C)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F13 compound treatment 58800.0 -36400.0 -3.34 18400.0 -75400.0 -6.99 -7.3045 -0.9431 3000979 BCB01_000111 CCCCCCCCCCC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F14 compound treatment 75600.0 -19600.0 -1.8 73200.0 -20600.0 -1.91 -2.6201 -0.9996 3000980 BCB01_000112 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc(O)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F15 compound treatment 79600.0 -15600.0 -1.43 76000.0 -17800.0 -1.65 -2.1764 -0.9976 3000981 BCB01_000113 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F16 compound treatment 71200.0 -24000.0 -2.2 63600.0 -30200.0 -2.8 -3.5355 -0.9931 3000982 BCB01_000114 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F17 compound treatment 73200.0 -22000.0 -2.02 68400.0 -25400.0 -2.35 -3.0908 -0.9972 3000984 BCB01_000115 COc1ccc(C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O)c4ccccc14 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F18 compound treatment 84400.0 -10800.0 -0.99 84400.0 -9360.0 -0.87 -1.3137 -0.9978 3093298 BCB01_000116 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F19 compound treatment 76800.0 -18400.0 -1.69 67200.0 -26600.0 -2.46 -2.9353 -0.9831 3093299 BCB01_000117 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F20 compound treatment 78000.0 -17200.0 -1.58 73200.0 -20600.0 -1.91 -2.464 -0.9956 3000987 BCB01_000118 CC(=O)N1CC(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F21 compound treatment 71600.0 -23600.0 -2.17 75200.0 -18600.0 -1.72 -2.7492 -0.9935 3093300 BCB01_000119 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F22 compound treatment 86400.0 -8760.0 -0.81 77600.0 -16200.0 -1.5 -1.6293 -0.9577 3093301 BCB01_000120 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccs4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F23 mock treatment 92800.0 -2360.0 -0.22 93200.0 -563.0 -0.05 -0.1905 -0.8526 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 F24 mock treatment 95600.0 438.0 0.04 93200.0 -563.0 -0.05 -0.0084 -0.1277 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G01 mock treatment 91600.0 -3560.0 -0.33 82400.0 -11400.0 -1.05 -0.9764 -0.8853 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G02 mock treatment 92800.0 -2360.0 -0.22 84000.0 -9760.0 -0.9 -0.7935 -0.8527 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G03 compound treatment 82000.0 -13200.0 -1.21 73600.0 -20200.0 -1.87 -2.1776 -0.9779 3000990 BCB01_000121 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G04 compound treatment 89600.0 -5560.0 -0.51 83200.0 -10600.0 -0.98 -1.0541 -0.9542 3093302 BCB01_000122 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G05 compound treatment 85600.0 -9560.0 -0.88 84000.0 -9760.0 -0.9 -1.2618 -0.9999 3093303 BCB01_000123 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G06 compound treatment 87600.0 -7560.0 -0.7 88000.0 -5760.0 -0.53 -0.8696 -0.9915 3000991 BCB01_000124 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G07 compound treatment 84000.0 -11200.0 -1.03 68000.0 -25800.0 -2.39 -2.4146 -0.9289 3093304 BCB01_000125 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G08 compound treatment 87600.0 -7560.0 -0.7 79200.0 -14600.0 -1.35 -1.4463 -0.9525 3000992 BCB01_000126 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G09 compound treatment 76800.0 -18400.0 -1.69 81200.0 -12600.0 -1.16 -2.0177 -0.9835 3093373 BCB01_000127 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G10 compound treatment 90800.0 -4360.0 -0.4 90800.0 -2960.0 -0.27 -0.4779 -0.9829 3093374 BCB01_000128 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G11 compound treatment 74000.0 -21200.0 -1.95 68000.0 -25800.0 -2.39 -3.065 -0.9949 3000993 BCB01_000129 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G12 compound treatment 84000.0 -11200.0 -1.03 80000.0 -13800.0 -1.28 -1.6281 -0.9942 3093375 BCB01_000130 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(C2C1=O)N5CCCCC5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G13 compound treatment 85600.0 -9560.0 -0.88 82800.0 -11000.0 -1.02 -1.3405 -0.9974 3093376 BCB01_000131 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G14 compound treatment 84800.0 -10400.0 -0.95 74800.0 -19000.0 -1.76 -1.9168 -0.9587 3000994 BCB01_000132 C/C=C/C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G15 compound treatment 71600.0 -23600.0 -2.17 68800.0 -25000.0 -2.31 -3.1687 -0.9995 3093377 BCB01_000133 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G16 compound treatment 80400.0 -14800.0 -1.36 88000.0 -5760.0 -0.53 -1.3379 -0.9169 3000995 BCB01_000134 CCC(CC)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G17 compound treatment 84000.0 -11200.0 -1.03 82400.0 -11400.0 -1.05 -1.4708 -0.9999 3093378 BCB01_000135 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccco5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G18 compound treatment 93600.0 -1560.0 -0.14 82000.0 -11800.0 -1.09 -0.8726 -0.7935 3000996 BCB01_000136 CC(C)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G19 compound treatment 84400.0 -10800.0 -0.99 80000.0 -13800.0 -1.28 -1.602 -0.9921 3093379 BCB01_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G20 compound treatment 90800.0 -4360.0 -0.4 86000.0 -7760.0 -0.72 -0.7925 -0.962 3093380 BCB01_000138 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G21 compound treatment 86000.0 -9160.0 -0.84 84400.0 -9360.0 -0.87 -1.2096 -0.9999 3000997 BCB01_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G22 compound treatment 87200.0 -7960.0 -0.73 84800.0 -8960.0 -0.83 -1.1053 -0.998 3093381 BCB01_000140 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G23 mock treatment 93600.0 -1560.0 -0.14 100000.0 6240.0 0.58 0.3072 0.5156 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 G24 mock treatment 96000.0 838.0 0.08 93600.0 -163.0 -0.02 0.0438 0.5583 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H01 mock treatment 95200.0 37.5 0.0 85600.0 -8160.0 -0.76 -0.5325 -0.7039 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H02 mock treatment 92000.0 -3160.0 -0.29 87200.0 -6560.0 -0.61 -0.6358 -0.943 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H03 compound treatment 65200.0 -30000.0 -2.76 58800.0 -35000.0 -3.24 -4.2403 -0.9968 3000998 BCB01_000141 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H04 compound treatment 84000.0 -11200.0 -1.03 73200.0 -20600.0 -1.91 -2.0737 -0.9579 3093382 BCB01_000142 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H05 compound treatment 85600.0 -9560.0 -0.88 86000.0 -7760.0 -0.72 -1.1307 -0.995 3093383 BCB01_000143 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H06 compound treatment 78800.0 -16400.0 -1.51 69600.0 -24200.0 -2.24 -2.6479 -0.9813 3000999 BCB01_000144 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(C#N)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H07 compound treatment 72400.0 -22800.0 -2.09 70800.0 -23000.0 -2.13 -2.9855 -1.0 3093384 BCB01_000145 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H08 compound treatment 76800.0 -18400.0 -1.69 77200.0 -16600.0 -1.54 -2.2799 -0.9989 3093385 BCB01_000146 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H09 compound treatment 68000.0 -27200.0 -2.5 65200.0 -28600.0 -2.65 -3.6388 -0.9996 3001000 BCB01_000147 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H10 compound treatment 71600.0 -23600.0 -2.17 67200.0 -26600.0 -2.46 -3.2735 -0.998 3001068 BCB01_000148 CC1(C)[C@H]2CC1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H11 compound treatment 69200.0 -26000.0 -2.39 72400.0 -21400.0 -1.98 -3.0888 -0.9957 3001069 BCB01_000149 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H12 compound treatment 87200.0 -7960.0 -0.73 75200.0 -18600.0 -1.72 -1.7345 -0.9276 3001070 BCB01_000150 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H13 compound treatment 88000.0 -7160.0 -0.66 79600.0 -14200.0 -1.31 -1.3941 -0.9492 3001072 BCB01_000151 C/C=C/C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H14 compound treatment 82400.0 -12800.0 -1.17 65200.0 -28600.0 -2.65 -2.7021 -0.933 3093386 BCB01_000152 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H15 compound treatment 82800.0 -12400.0 -1.14 88400.0 -5360.0 -0.5 -1.1556 -0.9311 3001073 BCB01_000153 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(NC(=O)OC(C)(C)C)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H16 compound treatment 88800.0 -6360.0 -0.59 86000.0 -7760.0 -0.72 -0.9226 -0.9947 3093387 BCB01_000154 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H17 compound treatment 84000.0 -11200.0 -1.03 85600.0 -8160.0 -0.76 -1.261 -0.9887 3093388 BCB01_000155 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H18 compound treatment 88400.0 -6760.0 -0.62 82400.0 -11400.0 -1.05 -1.1846 -0.9684 3001076 BCB01_000156 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(I)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H19 compound treatment 89600.0 -5560.0 -0.51 83600.0 -10200.0 -0.94 -1.0279 -0.9589 3093389 BCB01_000157 CC(C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H20 compound treatment 90800.0 -4360.0 -0.4 91600.0 -2160.0 -0.2 -0.4255 -0.9486 3093390 BCB01_000158 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H21 compound treatment 88400.0 -6760.0 -0.62 89600.0 -4160.0 -0.39 -0.7127 -0.9736 3001078 BCB01_000159 CC(CC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccc(C)o3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H22 compound treatment 88800.0 -6360.0 -0.59 94000.0 238.0 0.02 -0.3983 -0.68 3093391 BCB01_000160 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H23 mock treatment 98400.0 3240.0 0.3 95600.0 1840.0 0.17 0.331 0.9649 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 H24 mock treatment 91200.0 -3960.0 -0.36 95200.0 1440.0 0.13 -0.1635 -0.4213 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I01 mock treatment 98800.0 3640.0 0.33 92000.0 -1760.0 -0.16 0.1211 0.3252 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I02 mock treatment 95200.0 37.5 0.0 95600.0 1840.0 0.17 0.1229 0.7213 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I03 compound treatment 85200.0 -9960.0 -0.92 90800.0 -2960.0 -0.27 -0.8422 -0.8803 3001079 BCB01_000161 CN1C(=O)C2C=CC(C(O)c3cccc(O)c3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I04 compound treatment 89200.0 -5960.0 -0.55 82400.0 -11400.0 -1.05 -1.1325 -0.9538 3093392 BCB01_000162 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I05 compound treatment 88400.0 -6760.0 -0.62 77200.0 -16600.0 -1.54 -1.5254 -0.9209 3093393 BCB01_000163 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I06 compound treatment 78800.0 -16400.0 -1.51 79200.0 -14600.0 -1.35 -2.0187 -0.9985 3001081 BCB01_000164 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I07 compound treatment 81200.0 -14000.0 -1.28 80800.0 -13000.0 -1.2 -1.7577 -0.9994 3093394 BCB01_000165 CN1C(=O)C2C=CC(C(O)c3cn(C(=O)C)c4ccccc34)N(Nc5ccccc5)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I08 compound treatment 78000.0 -17200.0 -1.58 70000.0 -23800.0 -2.2 -2.6737 -0.9867 3093395 BCB01_000166 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I09 compound treatment 82000.0 -13200.0 -1.21 66800.0 -27000.0 -2.5 -2.6233 -0.9447 3001082 BCB01_000167 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I10 compound treatment 81200.0 -14000.0 -1.28 83600.0 -10200.0 -0.94 -1.5742 -0.9884 3093464 BCB01_000168 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I11 compound treatment 74000.0 -21200.0 -1.95 72800.0 -21000.0 -1.94 -2.7504 -1.0 3001083 BCB01_000169 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I12 compound treatment 82800.0 -12400.0 -1.14 83600.0 -10200.0 -0.94 -1.4702 -0.9956 3093465 BCB01_000170 CN1C(=O)C2C=CC(C(O)c3cccn3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I13 compound treatment 83600.0 -11600.0 -1.06 71200.0 -22600.0 -2.09 -2.2308 -0.9508 3093466 BCB01_000171 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccc(C)o4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I14 compound treatment 75600.0 -19600.0 -1.8 62800.0 -31000.0 -2.87 -3.3017 -0.9747 3001084 BCB01_000172 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I15 compound treatment 84000.0 -11200.0 -1.03 80400.0 -13400.0 -1.24 -1.6018 -0.9957 3093467 BCB01_000173 CN1C(=O)C2C=CC(C(O)c3cccs3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I16 compound treatment 75200.0 -20000.0 -1.84 72800.0 -21000.0 -1.94 -2.6723 -0.9996 3093468 BCB01_000174 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I17 compound treatment 64800.0 -30400.0 -2.79 58400.0 -35400.0 -3.28 -4.2926 -0.9968 3001085 BCB01_000175 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I18 compound treatment 83200.0 -12000.0 -1.1 82800.0 -11000.0 -1.02 -1.4966 -0.9992 3093469 BCB01_000176 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I19 compound treatment 80000.0 -15200.0 -1.39 79200.0 -14600.0 -1.35 -1.9407 -0.9999 3001086 BCB01_000177 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccccc5)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I20 compound treatment 81200.0 -14000.0 -1.28 76000.0 -17800.0 -1.65 -2.0723 -0.9925 3093470 BCB01_000178 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I21 compound treatment 86800.0 -8360.0 -0.77 86400.0 -7360.0 -0.68 -1.0265 -0.9982 3001087 BCB01_000179 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I22 compound treatment 90800.0 -4360.0 -0.4 78400.0 -15400.0 -1.42 -1.2906 -0.8724 3093471 BCB01_000180 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I23 mock treatment 99600.0 4440.0 0.41 94000.0 238.0 0.02 0.3042 0.7442 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 I24 mock treatment 98400.0 3240.0 0.3 94000.0 238.0 0.02 0.2261 0.7573 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J01 mock treatment 94800.0 -363.0 -0.03 92000.0 -1760.0 -0.16 -0.1391 -0.8342 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J02 mock treatment 95600.0 438.0 0.04 91200.0 -2560.0 -0.24 -0.1395 -0.579 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J03 compound treatment 96000.0 838.0 0.08 90400.0 -3360.0 -0.31 -0.1659 -0.5168 3093472 BCB01_000181 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J04 compound treatment 88800.0 -6360.0 -0.59 92800.0 -963.0 -0.09 -0.4769 -0.8056 3001088 BCB01_000182 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J05 compound treatment 70800.0 -24400.0 -2.24 62400.0 -31400.0 -2.91 -3.6402 -0.9917 3093473 BCB01_000183 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J06 compound treatment 91600.0 -3560.0 -0.33 85600.0 -8160.0 -0.76 -0.7667 -0.9299 3093474 BCB01_000184 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J07 compound treatment 81200.0 -14000.0 -1.28 80000.0 -13800.0 -1.28 -1.8102 -1.0 3001089 BCB01_000185 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J08 compound treatment 78800.0 -16400.0 -1.51 84400.0 -9360.0 -0.87 -1.6779 -0.9658 3001153 BCB01_000186 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J09 compound treatment 58000.0 -37200.0 -3.42 42800.0 -51000.0 -4.72 -5.7573 -0.9874 3001154 BCB01_000187 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J10 compound treatment 84400.0 -10800.0 -0.99 82000.0 -11800.0 -1.09 -1.471 -0.9988 3001156 BCB01_000188 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J11 compound treatment 76800.0 -18400.0 -1.69 79200.0 -14600.0 -1.35 -2.1488 -0.9938 3001157 BCB01_000189 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J12 compound treatment 85600.0 -9560.0 -0.88 85200.0 -8560.0 -0.79 -1.1832 -0.9987 3093475 BCB01_000190 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J13 compound treatment 83200.0 -12000.0 -1.1 77600.0 -16200.0 -1.5 -1.8374 -0.9885 3093476 BCB01_000191 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J14 compound treatment 94000.0 -1160.0 -0.11 84800.0 -8960.0 -0.83 -0.663 -0.7916 3001159 BCB01_000192 CCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J15 compound treatment 78000.0 -17200.0 -1.58 84800.0 -8960.0 -0.83 -1.7037 -0.955 3093477 BCB01_000193 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J16 compound treatment 64000.0 -31200.0 -2.87 55600.0 -38200.0 -3.54 -4.5281 -0.9946 3001160 BCB01_000194 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J17 compound treatment 70400.0 -24800.0 -2.28 62800.0 -31000.0 -2.87 -3.64 -0.9934 3093478 BCB01_000195 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J18 compound treatment 86800.0 -8360.0 -0.77 86400.0 -7360.0 -0.68 -1.0265 -0.9982 3093479 BCB01_000196 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J19 compound treatment 87600.0 -7560.0 -0.7 88400.0 -5360.0 -0.5 -0.8434 -0.9864 3001161 BCB01_000197 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J20 compound treatment 86000.0 -9160.0 -0.84 83200.0 -10600.0 -0.98 -1.2882 -0.9972 3093480 BCB01_000198 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J21 compound treatment 83200.0 -12000.0 -1.1 77600.0 -16200.0 -1.5 -1.8374 -0.9885 3093481 BCB01_000199 CCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J22 compound treatment 94000.0 -1160.0 -0.11 92800.0 -963.0 -0.09 -0.1387 -0.9959 3001163 BCB01_000200 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J23 mock treatment 96800.0 1640.0 0.15 91600.0 -2160.0 -0.2 -0.0352 -0.1405 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 J24 mock treatment 94400.0 -763.0 -0.07 90400.0 -3360.0 -0.31 -0.27 -0.8451 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K01 mock treatment 92800.0 -2360.0 -0.22 85200.0 -8560.0 -0.79 -0.7149 -0.8687 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K02 mock treatment 92000.0 -3160.0 -0.29 87600.0 -6160.0 -0.57 -0.6096 -0.951 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K03 compound treatment 95600.0 438.0 0.04 88800.0 -4960.0 -0.46 -0.2968 -0.6428 3093482 BCB01_000201 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccccc4)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K04 compound treatment 78400.0 -16800.0 -1.54 81600.0 -12200.0 -1.13 -1.8874 -0.9882 3001164 BCB01_000202 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K05 compound treatment 50800.0 -44400.0 -4.08 40000.0 -53800.0 -4.98 -6.4092 -0.9951 3093483 BCB01_000203 CN1C(=O)C2C=CC(C(O)/C=C(\C)/CCC=C(C)C)N(Nc3ccccc3)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K06 compound treatment 77200.0 -18000.0 -1.65 77200.0 -16600.0 -1.54 -2.2539 -0.9993 3093484 BCB01_000204 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K07 compound treatment 83200.0 -12000.0 -1.1 83200.0 -10600.0 -0.98 -1.4704 -0.9983 3000112 BCB01_000205 CN1C(=O)C2C=CC(C(O)C(C)(C)C)N(Nc3ccccc3)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K08 compound treatment 81200.0 -14000.0 -1.28 81600.0 -12200.0 -1.13 -1.7053 -0.9979 3000114 BCB01_000206 COc1ccc(cc1)C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K09 compound treatment 86000.0 -9160.0 -0.84 74400.0 -19400.0 -1.79 -1.865 -0.9406 3000115 BCB01_000207 CCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K10 compound treatment 82800.0 -12400.0 -1.14 81200.0 -12600.0 -1.16 -1.6275 -0.9999 3000116 BCB01_000208 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K11 compound treatment 64000.0 -31200.0 -2.87 64800.0 -29000.0 -2.68 -3.9251 -0.9995 3000118 BCB01_000209 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K12 compound treatment 78400.0 -16800.0 -1.54 74000.0 -19800.0 -1.83 -2.3855 -0.9963 3093485 BCB01_000210 CCCCC(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K13 compound treatment 66800.0 -28400.0 -2.61 62000.0 -31800.0 -2.94 -3.9265 -0.9982 3093645 BCB01_000211 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K14 compound treatment 86000.0 -9160.0 -0.84 82000.0 -11800.0 -1.09 -1.3669 -0.9919 3000120 BCB01_000212 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K15 compound treatment 85600.0 -9560.0 -0.88 84800.0 -8960.0 -0.83 -1.2094 -0.9996 3093555 BCB01_000213 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K16 compound treatment 84400.0 -10800.0 -0.99 77200.0 -16600.0 -1.54 -1.7856 -0.9775 3093556 BCB01_000214 COc1ccc(C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K17 compound treatment 75600.0 -19600.0 -1.8 82000.0 -11800.0 -1.09 -2.0433 -0.9712 3000122 BCB01_000215 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K18 compound treatment 80800.0 -14400.0 -1.32 73600.0 -20200.0 -1.87 -2.2557 -0.9856 3093557 BCB01_000216 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K19 compound treatment 86000.0 -9160.0 -0.84 92400.0 -1360.0 -0.13 -0.6853 -0.8041 3000123 BCB01_000217 OC(C#Cc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K20 compound treatment 79200.0 -16000.0 -1.47 84000.0 -9760.0 -0.9 -1.6781 -0.973 3093558 BCB01_000218 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(C2C1=O)N(c5ccccc5)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K21 compound treatment 74400.0 -20800.0 -1.91 77600.0 -16200.0 -1.5 -2.4098 -0.9928 3093559 BCB01_000219 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K22 compound treatment 89600.0 -5560.0 -0.51 92800.0 -963.0 -0.09 -0.4249 -0.8181 3000124 BCB01_000220 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K23 mock treatment 94400.0 -763.0 -0.07 104400.0 10600.0 0.99 0.6476 0.6552 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 K24 mock treatment 90000.0 -5160.0 -0.47 95600.0 1840.0 0.17 -0.2153 -0.4269 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L01 mock treatment 95200.0 37.5 0.0 94000.0 238.0 0.02 0.018 0.808 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L02 mock treatment 93200.0 -1960.0 -0.18 94800.0 1040.0 0.1 -0.0596 -0.2916 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L03 compound treatment 75200.0 -20000.0 -1.84 72000.0 -21800.0 -2.02 -2.7248 -0.9989 3093560 BCB01_000221 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L04 compound treatment 84800.0 -10400.0 -0.95 80000.0 -13800.0 -1.28 -1.576 -0.9897 3093561 BCB01_000222 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L05 compound treatment 87600.0 -7560.0 -0.7 87600.0 -6160.0 -0.57 -0.8958 -0.9952 3000127 BCB01_000223 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L06 compound treatment 89600.0 -5560.0 -0.51 90800.0 -2960.0 -0.27 -0.556 -0.9574 3093562 BCB01_000224 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L07 compound treatment 80800.0 -14400.0 -1.32 82000.0 -11800.0 -1.09 -1.7051 -0.9954 3093563 BCB01_000225 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L08 compound treatment 88000.0 -7160.0 -0.66 94400.0 638.0 0.06 -0.4241 -0.6411 3000128 BCB01_000226 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L09 compound treatment 88000.0 -7160.0 -0.66 81600.0 -12200.0 -1.13 -1.263 -0.9673 3093564 BCB01_000227 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L10 compound treatment 86800.0 -8360.0 -0.77 82800.0 -11000.0 -1.02 -1.2624 -0.9906 3000129 BCB01_000228 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4c(F)cccc4Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L11 compound treatment 75600.0 -19600.0 -1.8 70400.0 -23400.0 -2.17 -2.8036 -0.9958 3093565 BCB01_000229 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L12 compound treatment 86400.0 -8760.0 -0.81 83200.0 -10600.0 -0.98 -1.2622 -0.9953 3093566 BCB01_000230 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L13 compound treatment 78000.0 -17200.0 -1.58 82800.0 -11000.0 -1.02 -1.8348 -0.9773 3000131 BCB01_000231 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L14 compound treatment 54400.0 -40800.0 -3.75 61600.0 -32200.0 -2.98 -4.7593 -0.9935 3093567 BCB01_000232 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L15 compound treatment 70000.0 -25200.0 -2.31 64800.0 -29000.0 -2.68 -3.5349 -0.9973 3093568 BCB01_000233 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L16 compound treatment 94000.0 -1160.0 -0.11 86400.0 -7360.0 -0.68 -0.5582 -0.808 3000133 BCB01_000234 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L17 compound treatment 82800.0 -12400.0 -1.14 77600.0 -16200.0 -1.5 -1.8634 -0.9907 3093569 BCB01_000235 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L18 compound treatment 91600.0 -3560.0 -0.33 86400.0 -7360.0 -0.68 -0.7143 -0.9435 3000205 BCB01_000236 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L19 compound treatment 83600.0 -11600.0 -1.06 75600.0 -18200.0 -1.68 -1.9425 -0.9755 3000206 BCB01_000237 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L20 compound treatment 94800.0 -363.0 -0.03 87200.0 -6560.0 -0.61 -0.4537 -0.7448 3000207 BCB01_000238 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L21 compound treatment 81600.0 -13600.0 -1.25 77200.0 -16600.0 -1.54 -1.9677 -0.9947 3000208 BCB01_000239 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L22 compound treatment 84800.0 -10400.0 -0.95 89600.0 -4160.0 -0.39 -0.9468 -0.9208 3093570 BCB01_000240 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L23 mock treatment 97600.0 2440.0 0.22 95600.0 1840.0 0.17 0.279 0.9908 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 L24 mock treatment 90800.0 -4360.0 -0.4 92000.0 -1760.0 -0.16 -0.3993 -0.9215 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M01 mock treatment 90800.0 -4360.0 -0.4 88400.0 -5360.0 -0.5 -0.6352 -0.9944 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M02 mock treatment 105200.0 10000.0 0.92 90400.0 -3360.0 -0.31 0.4325 0.4438 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M03 compound treatment 82800.0 -12400.0 -1.14 90800.0 -2960.0 -0.27 -0.9983 -0.8533 3000209 BCB01_000241 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M04 compound treatment 94000.0 -1160.0 -0.11 86800.0 -6960.0 -0.65 -0.5319 -0.8132 3093571 BCB01_000242 C/C=C/C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M05 compound treatment 86800.0 -8360.0 -0.77 81200.0 -12600.0 -1.16 -1.3673 -0.9797 3093572 BCB01_000243 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M06 compound treatment 87200.0 -7960.0 -0.73 86400.0 -7360.0 -0.68 -1.0005 -0.9994 3000211 BCB01_000244 CC(C)C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M07 compound treatment 83600.0 -11600.0 -1.06 80000.0 -13800.0 -1.28 -1.6541 -0.9959 3093573 BCB01_000245 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M08 compound treatment 88000.0 -7160.0 -0.66 77600.0 -16200.0 -1.5 -1.5252 -0.9319 3093574 BCB01_000246 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M09 compound treatment 81600.0 -13600.0 -1.25 74800.0 -19000.0 -1.76 -2.125 -0.9859 3000213 BCB01_000247 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M10 compound treatment 77200.0 -18000.0 -1.65 76800.0 -17000.0 -1.57 -2.2801 -0.9997 3093575 BCB01_000248 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M11 compound treatment 61600.0 -33600.0 -3.09 55200.0 -38600.0 -3.57 -4.7105 -0.9973 3000215 BCB01_000249 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M12 compound treatment 84000.0 -11200.0 -1.03 79200.0 -14600.0 -1.35 -1.6805 -0.9909 3093576 BCB01_000250 CC(C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M13 compound treatment 72000.0 -23200.0 -2.13 70400.0 -23400.0 -2.17 -3.0378 -1.0 3093646 BCB01_000251 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M14 compound treatment 88000.0 -7160.0 -0.66 83600.0 -10200.0 -0.94 -1.1319 -0.9847 3000219 BCB01_000252 CN1C(=O)C2C=CC(C(O)c3cccs3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M15 compound treatment 66000.0 -29200.0 -2.68 67600.0 -26200.0 -2.43 -3.6115 -0.9987 3093647 BCB01_000253 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M16 compound treatment 80000.0 -15200.0 -1.39 82000.0 -11800.0 -1.09 -1.7571 -0.9926 3000221 BCB01_000254 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M17 compound treatment 92400.0 -2760.0 -0.25 84800.0 -8960.0 -0.83 -0.7671 -0.883 3093648 BCB01_000255 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M18 compound treatment 76400.0 -18800.0 -1.73 76800.0 -17000.0 -1.57 -2.3321 -0.9989 3093649 BCB01_000256 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M19 compound treatment 77600.0 -17600.0 -1.62 80000.0 -13800.0 -1.28 -2.0443 -0.9932 3000223 BCB01_000257 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M20 compound treatment 76400.0 -18800.0 -1.73 83200.0 -10600.0 -0.98 -1.9126 -0.9639 3093650 BCB01_000258 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M21 compound treatment 38800.0 -56400.0 -5.18 41600.0 -52200.0 -4.83 -7.0848 -0.9994 3093651 BCB01_000259 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M22 compound treatment 92000.0 -3160.0 -0.29 92000.0 -1760.0 -0.16 -0.3212 -0.9628 3000225 BCB01_000260 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M23 mock treatment 99600.0 4440.0 0.41 94000.0 238.0 0.02 0.3042 0.7442 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 M24 mock treatment 91600.0 -3560.0 -0.33 92000.0 -1760.0 -0.16 -0.3472 -0.9483 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N01 mock treatment 88400.0 -6760.0 -0.62 101200.0 7440.0 0.69 0.0476 0.0513 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N02 mock treatment 98400.0 3240.0 0.3 98400.0 4640.0 0.43 0.5145 0.9839 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N03 compound treatment 72400.0 -22800.0 -2.09 66000.0 -27800.0 -2.57 -3.3001 -0.9948 3093652 BCB01_000261 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N04 compound treatment 95200.0 37.5 0.0 94000.0 238.0 0.02 0.018 0.808 3093653 BCB01_000262 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N05 compound treatment 93200.0 -1960.0 -0.18 84000.0 -9760.0 -0.9 -0.7675 -0.8318 3000227 BCB01_000263 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N06 compound treatment 93200.0 -1960.0 -0.18 95200.0 1440.0 0.13 -0.0334 -0.149 3093654 BCB01_000264 C/C=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N07 compound treatment 86800.0 -8360.0 -0.77 82800.0 -11000.0 -1.02 -1.2624 -0.9906 3093655 BCB01_000265 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N08 compound treatment 92800.0 -2360.0 -0.22 80400.0 -13400.0 -1.24 -1.0295 -0.8187 3000229 BCB01_000266 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N09 compound treatment 82000.0 -13200.0 -1.21 81600.0 -12200.0 -1.13 -1.6533 -0.9994 3093656 BCB01_000267 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N10 compound treatment 95600.0 438.0 0.04 85200.0 -8560.0 -0.79 -0.5327 -0.6704 3000231 BCB01_000268 CC(C)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N11 compound treatment 74000.0 -21200.0 -1.95 76400.0 -17400.0 -1.61 -2.5144 -0.9955 3093657 BCB01_000269 CC(C)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N12 compound treatment 95600.0 438.0 0.04 84000.0 -9760.0 -0.9 -0.6114 -0.675 3000297 BCB01_000270 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N13 compound treatment 84400.0 -10800.0 -0.99 85200.0 -8560.0 -0.79 -1.2612 -0.994 3000298 BCB01_000271 OB(O)c1ccc(cc1)C(O)C2C=CC3CN(C(=O)C3N2Nc4ccc(C#N)cc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N14 compound treatment 91200.0 -3960.0 -0.36 98000.0 4240.0 0.39 0.02 0.0373 3000299 BCB01_000272 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N15 compound treatment 80000.0 -15200.0 -1.39 78000.0 -15800.0 -1.46 -2.0193 -0.9997 3093658 BCB01_000273 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N16 compound treatment 89600.0 -5560.0 -0.51 86800.0 -6960.0 -0.65 -0.8181 -0.9934 3093659 BCB01_000274 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N17 compound treatment 85200.0 -9960.0 -0.92 84400.0 -9360.0 -0.87 -1.2616 -0.9996 3000301 BCB01_000275 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N18 compound treatment 95200.0 37.5 0.0 93200.0 -563.0 -0.05 -0.0344 -0.6589 3093660 BCB01_000276 CC(C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N19 compound treatment 91200.0 -3960.0 -0.36 92800.0 -963.0 -0.09 -0.3208 -0.8549 3093661 BCB01_000277 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N20 compound treatment 89600.0 -5560.0 -0.51 92800.0 -963.0 -0.09 -0.4249 -0.8181 3000302 BCB01_000278 CC(CC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C)o4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N21 compound treatment 76000.0 -19200.0 -1.76 77600.0 -16200.0 -1.5 -2.3057 -0.9967 3093662 BCB01_000279 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N22 compound treatment 96800.0 1640.0 0.15 92000.0 -1760.0 -0.16 -0.009 -0.0406 3093663 BCB01_000280 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccs4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N23 mock treatment 100000.0 4840.0 0.44 101200.0 7440.0 0.69 0.8021 0.9776 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 N24 mock treatment 95200.0 37.5 0.0 98400.0 4640.0 0.43 0.3064 0.7128 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O01 mock treatment 85600.0 -9560.0 -0.88 100400.0 6640.0 0.62 -0.1869 -0.1742 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O02 mock treatment 102800.0 7640.0 0.7 105200.0 11400.0 1.06 1.2464 0.98 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O03 compound treatment 86800.0 -8360.0 -0.77 86000.0 -7760.0 -0.72 -1.0527 -0.9994 3000303 BCB01_000281 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O04 compound treatment 100800.0 5640.0 0.52 96000.0 2240.0 0.21 0.5133 0.9191 3093664 BCB01_000282 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O05 compound treatment 82400.0 -12800.0 -1.17 92000.0 -1760.0 -0.16 -0.9456 -0.7978 3093665 BCB01_000283 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O06 compound treatment 92400.0 -2760.0 -0.25 103600.0 9840.0 0.91 0.4651 0.4913 3000304 BCB01_000284 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O07 compound treatment 99200.0 4040.0 0.37 95600.0 1840.0 0.17 0.383 0.9375 3093666 BCB01_000285 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O08 compound treatment 99200.0 4040.0 0.37 94800.0 1040.0 0.1 0.3306 0.8618 3093667 BCB01_000286 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)C(=O)C)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O09 compound treatment 81600.0 -13600.0 -1.25 81200.0 -12600.0 -1.16 -1.7055 -0.9994 3000307 BCB01_000287 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O10 compound treatment 88000.0 -7160.0 -0.66 85600.0 -8160.0 -0.76 -1.0009 -0.9976 3093736 BCB01_000288 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O11 compound treatment 86400.0 -8760.0 -0.81 81600.0 -12200.0 -1.13 -1.3671 -0.9865 3000308 BCB01_000289 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O12 compound treatment 95600.0 438.0 0.04 92400.0 -1360.0 -0.13 -0.0608 -0.459 3093737 BCB01_000290 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O13 compound treatment 90000.0 -5160.0 -0.47 82000.0 -11800.0 -1.09 -1.1067 -0.9306 3093738 BCB01_000291 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O14 compound treatment 84000.0 -11200.0 -1.03 85600.0 -8160.0 -0.76 -1.261 -0.9887 3000310 BCB01_000292 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O15 compound treatment 74000.0 -21200.0 -1.95 74800.0 -19000.0 -1.76 -2.6193 -0.9987 3093739 BCB01_000293 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O16 compound treatment 97200.0 2040.0 0.19 93600.0 -163.0 -0.02 0.1219 0.6482 3000311 BCB01_000294 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O17 compound treatment 75600.0 -19600.0 -1.8 77600.0 -16200.0 -1.5 -2.3317 -0.9959 3093740 BCB01_000295 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O18 compound treatment 95200.0 37.5 0.0 90800.0 -2960.0 -0.27 -0.1917 -0.6982 3093741 BCB01_000296 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O19 compound treatment 99600.0 4440.0 0.41 95600.0 1840.0 0.17 0.4091 0.9249 3000313 BCB01_000297 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O20 compound treatment 84000.0 -11200.0 -1.03 76400.0 -17400.0 -1.61 -1.864 -0.9764 3093742 BCB01_000298 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O21 compound treatment 91600.0 -3560.0 -0.33 85600.0 -8160.0 -0.76 -0.7667 -0.9299 3000315 BCB01_000299 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O22 compound treatment 88400.0 -6760.0 -0.62 84400.0 -9360.0 -0.87 -1.0535 -0.9867 3093743 BCB01_000300 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)C(C)C)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O23 mock treatment 101200.0 6040.0 0.56 102400.0 8640.0 0.8 0.9588 0.984 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 O24 mock treatment 104000.0 8840.0 0.81 91200.0 -2560.0 -0.24 0.4069 0.4804 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P01 mock treatment 95200.0 37.5 0.0 98000.0 4240.0 0.39 0.2802 0.7133 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P02 mock treatment 103200.0 8040.0 0.74 102800.0 9040.0 0.84 1.1151 0.9981 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P03 compound treatment 96800.0 1640.0 0.15 102800.0 9040.0 0.84 0.6988 0.8211 3000135 BCB01_000301 CC(C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P04 compound treatment 99200.0 4040.0 0.37 96000.0 2240.0 0.21 0.4093 0.9621 3000137 BCB01_000302 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P05 compound treatment 72400.0 -22800.0 -2.09 48800.0 -45000.0 -4.17 -4.4275 -0.9493 3000138 BCB01_000303 CC(CC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P06 compound treatment 112400.0 17200.0 1.59 100800.0 7040.0 0.65 1.5824 0.923 3000139 BCB01_000304 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C#N)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P07 compound treatment 93200.0 -1960.0 -0.18 87600.0 -6160.0 -0.57 -0.5315 -0.8873 3093744 BCB01_000305 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P08 compound treatment 96000.0 838.0 0.08 95200.0 1440.0 0.13 0.1487 0.9661 3000141 BCB01_000306 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P09 compound treatment 90400.0 -4760.0 -0.44 79200.0 -14600.0 -1.35 -1.2642 -0.8909 3093745 BCB01_000307 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P10 compound treatment 101200.0 6040.0 0.56 93600.0 -163.0 -0.02 0.382 0.6877 3093746 BCB01_000308 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P11 compound treatment 100400.0 5240.0 0.48 86800.0 -6960.0 -0.65 -0.1157 -0.1436 3000143 BCB01_000309 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P12 compound treatment 93200.0 -1960.0 -0.18 85600.0 -8160.0 -0.76 -0.6626 -0.8519 3093747 BCB01_000310 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P13 compound treatment 79600.0 -15600.0 -1.43 70800.0 -23000.0 -2.13 -2.5172 -0.9814 3093748 BCB01_000311 CC(=CCC/C=C(\C)/C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P14 compound treatment 96000.0 838.0 0.08 93600.0 -163.0 -0.02 0.0438 0.5583 3000145 BCB01_000312 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P15 compound treatment 54400.0 -40800.0 -3.75 64000.0 -29800.0 -2.76 -4.602 -0.9886 3093749 BCB01_000313 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P16 compound treatment 98800.0 3640.0 0.33 94000.0 238.0 0.02 0.2522 0.752 3093750 BCB01_000314 OCC(O)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P17 compound treatment 82400.0 -12800.0 -1.17 83600.0 -10200.0 -0.94 -1.4962 -0.994 3000147 BCB01_000315 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(I)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P18 compound treatment 95200.0 37.5 0.0 92800.0 -963.0 -0.09 -0.0606 -0.6793 3093751 BCB01_000316 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P19 compound treatment 85600.0 -9560.0 -0.88 78400.0 -15400.0 -1.42 -1.6289 -0.9732 3093752 BCB01_000317 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P20 compound treatment 91200.0 -3960.0 -0.36 98400.0 4640.0 0.43 0.0462 0.082 3000149 BCB01_000318 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P21 compound treatment 87200.0 -7960.0 -0.73 90000.0 -3760.0 -0.35 -0.7645 -0.9424 3093752 BCB01_000319 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P22 compound treatment 92800.0 -2360.0 -0.22 87600.0 -6160.0 -0.57 -0.5576 -0.9123 3093753 BCB01_000320 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P23 mock treatment 99600.0 4440.0 0.41 104000.0 10200.0 0.95 0.9596 0.929 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2000 P24 mock treatment 98400.0 3240.0 0.3 90000.0 -3760.0 -0.35 -0.036 -0.0786 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A01 compound treatment 112400.0 7200.0 0.66 105200.0 3580.0 0.33 0.703 0.9492 3000745 BCB02_000001 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A02 compound treatment 112800.0 7600.0 0.7 99600.0 -2020.0 -0.19 0.362 0.5005 3000746 BCB02_000002 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A03 compound treatment 106800.0 1600.0 0.15 99200.0 -2420.0 -0.22 -0.0545 -0.2034 3000747 BCB02_000003 OC(C1CCCCC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A04 compound treatment 98000.0 -7200.0 -0.66 102800.0 1180.0 0.11 -0.3909 -0.582 3000748 BCB02_000004 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A05 compound treatment 100000.0 -5200.0 -0.48 105600.0 3980.0 0.37 -0.0773 -0.1278 3000749 BCB02_000005 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A06 compound treatment 98800.0 -6400.0 -0.59 103600.0 1980.0 0.18 -0.2864 -0.4642 3000750 BCB02_000006 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A07 compound treatment 110000.0 4800.0 0.44 97600.0 -4020.0 -0.37 0.0488 0.0846 3093754 BCB02_000007 CCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A08 compound treatment 103200.0 -2000.0 -0.18 105200.0 3580.0 0.33 0.1046 0.2754 2065163 BCB02_000008 CCOC(=O)/C=C/c1ccccc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A09 compound treatment 102800.0 -2400.0 -0.22 96400.0 -5220.0 -0.48 -0.4981 -0.9371 3093755 BCB02_000009 CCCCCCCCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A10 compound treatment 107600.0 2400.0 0.22 98000.0 -3620.0 -0.34 -0.0811 -0.2021 3000752 BCB02_000010 CCOC(=O)/C=C/c1cc(F)ccc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A11 compound treatment 105200.0 -3.05 0.0 101200.0 -416.0 -0.04 -0.0274 -0.7122 3093756 BCB02_000011 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A12 compound treatment 93600.0 -11600.0 -1.07 79200.0 -22400.0 -2.08 -2.2239 -0.9521 3000753 BCB02_000012 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A13 compound treatment 105200.0 -3.05 0.0 100800.0 -816.0 -0.08 -0.0537 -0.7097 3093757 BCB02_000013 COc1ccc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A14 compound treatment 121600.0 16400.0 1.51 122000.0 20400.0 1.89 2.4025 0.9938 3000754 BCB02_000014 CCOC(=O)/C=C/c1cccc(OC)c1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A15 compound treatment 104800.0 -403.0 -0.04 99200.0 -2420.0 -0.22 -0.1845 -0.8131 3093824 BCB02_000015 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A16 compound treatment 131200.0 26000.0 2.39 126400.0 24800.0 2.3 3.3153 0.9998 3000755 BCB02_000016 CCOC(=O)/C=C/c1cccc(C)c1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A17 mock treatment 106800.0 1600.0 0.15 98800.0 -2820.0 -0.26 -0.0807 -0.2694 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A18 mock treatment 101200.0 -4000.0 -0.37 101200.0 -416.0 -0.04 -0.2876 -0.7768 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A19 mock treatment 102400.0 -2800.0 -0.26 102000.0 384.0 0.04 -0.1571 -0.6037 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A20 mock treatment 109200.0 4000.0 0.37 103600.0 1980.0 0.18 0.39 0.9488 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A21 mock treatment 110800.0 5600.0 0.51 112400.0 10800.0 1.0 1.0709 0.9524 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A22 mock treatment 104800.0 -403.0 -0.04 102400.0 784.0 0.07 0.0252 0.3087 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A23 mock treatment 109200.0 4000.0 0.37 101200.0 -416.0 -0.04 0.2327 0.6296 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 A24 mock treatment 100400.0 -4800.0 -0.44 98400.0 -3220.0 -0.3 -0.5232 -0.9816 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B01 compound treatment 102800.0 -2400.0 -0.22 103200.0 1580.0 0.15 -0.0525 -0.1977 3093825 BCB02_000017 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B02 compound treatment 119200.0 14000.0 1.29 109600.0 7980.0 0.74 1.4337 0.9654 3000756 BCB02_000018 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B03 compound treatment 112400.0 7200.0 0.66 106000.0 4380.0 0.41 0.7555 0.9726 3093826 BCB02_000019 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B04 compound treatment 92400.0 -12800.0 -1.18 97600.0 -4020.0 -0.37 -1.0959 -0.8873 3000757 BCB02_000020 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B05 compound treatment 104400.0 -803.0 -0.07 105200.0 3580.0 0.33 0.1827 0.5368 3093827 BCB02_000021 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(s5)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B06 compound treatment 104800.0 -403.0 -0.04 94000.0 -7620.0 -0.71 -0.5254 -0.7432 3093828 BCB02_000022 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B07 compound treatment 104400.0 -803.0 -0.07 100800.0 -816.0 -0.08 -0.1057 -0.9999 3000758 BCB02_000023 CC(C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B08 compound treatment 104400.0 -803.0 -0.07 100000.0 -1620.0 -0.15 -0.1581 -0.947 3093829 BCB02_000024 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B09 compound treatment 100400.0 -4800.0 -0.44 95600.0 -6020.0 -0.56 -0.7067 -0.9934 3000759 BCB02_000025 CC(CC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(C)o5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B10 compound treatment 106000.0 797.0 0.07 107600.0 5980.0 0.55 0.4441 0.7937 3093830 BCB02_000026 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B11 compound treatment 108000.0 2800.0 0.26 97200.0 -4420.0 -0.41 -0.1075 -0.2223 3093831 BCB02_000027 OC(Cc1ccccc1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B12 compound treatment 108400.0 3200.0 0.29 106400.0 4780.0 0.44 0.5215 0.9801 3000760 BCB02_000028 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B13 compound treatment 101600.0 -3600.0 -0.33 90000.0 -11600.0 -1.08 -0.9957 -0.8838 3093832 BCB02_000029 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B14 compound treatment 104800.0 -403.0 -0.04 104000.0 2380.0 0.22 0.1301 0.5804 3093833 BCB02_000030 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B15 compound treatment 97200.0 -8000.0 -0.74 94800.0 -6820.0 -0.63 -0.9672 -0.9971 3000761 BCB02_000031 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B16 compound treatment 102400.0 -2800.0 -0.26 108400.0 6780.0 0.63 0.2623 0.386 3093834 BCB02_000032 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B17 mock treatment 106000.0 797.0 0.07 102400.0 784.0 0.07 0.1032 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B18 mock treatment 106000.0 797.0 0.07 109600.0 7980.0 0.74 0.5751 0.7734 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B19 mock treatment 114000.0 8800.0 0.81 104800.0 3180.0 0.3 0.7809 0.9066 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B20 mock treatment 118800.0 13600.0 1.25 101600.0 -15.6 0.0 0.8834 0.7063 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B21 mock treatment 113200.0 8000.0 0.74 104400.0 2780.0 0.26 0.7026 0.9013 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B22 mock treatment 110000.0 4800.0 0.44 117200.0 15600.0 1.44 1.3334 0.8828 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B23 mock treatment 107600.0 2400.0 0.22 117200.0 15600.0 1.44 1.1773 0.8057 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 B24 mock treatment 105600.0 397.0 0.04 109600.0 7980.0 0.74 0.5491 0.7411 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C01 compound treatment 94000.0 -11200.0 -1.03 92400.0 -9220.0 -0.85 -1.3327 -0.9957 3093835 BCB02_000033 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C02 compound treatment 104000.0 -1200.0 -0.11 100400.0 -1220.0 -0.11 -0.1579 -1.0 3000762 BCB02_000034 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C03 compound treatment 103200.0 -2000.0 -0.18 88800.0 -12800.0 -1.19 -0.9702 -0.8071 3000763 BCB02_000035 Cc1ccccc1C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C04 compound treatment 104800.0 -403.0 -0.04 90400.0 -11200.0 -1.04 -0.7613 -0.7319 3093836 BCB02_000036 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C05 compound treatment 94000.0 -11200.0 -1.03 96000.0 -5620.0 -0.52 -1.0967 -0.95 3093837 BCB02_000037 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C06 compound treatment 95600.0 -9600.0 -0.88 96400.0 -5220.0 -0.48 -0.9664 -0.9598 3000764 BCB02_000038 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C07 compound treatment 95200.0 -10000.0 -0.92 90000.0 -11600.0 -1.08 -1.4119 -0.9969 3093838 BCB02_000039 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C08 compound treatment 91200.0 -14000.0 -1.29 83600.0 -18000.0 -1.67 -2.0916 -0.9918 3000765 BCB02_000040 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C09 compound treatment 105600.0 397.0 0.04 98000.0 -3620.0 -0.34 -0.2112 -0.6264 3093839 BCB02_000041 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C10 compound treatment 92400.0 -12800.0 -1.18 92400.0 -9220.0 -0.85 -1.4368 -0.9876 3000766 BCB02_000042 O=c1oc2ccccc2cc1C#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C11 compound treatment 93200.0 -12000.0 -1.1 96800.0 -4820.0 -0.45 -1.0963 -0.9206 3093840 BCB02_000043 OC(C1CCC=CC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C12 compound treatment 102000.0 -3200.0 -0.29 96800.0 -4820.0 -0.45 -0.524 -0.9797 3000767 BCB02_000044 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C13 compound treatment 101600.0 -3600.0 -0.33 98800.0 -2820.0 -0.26 -0.4189 -0.993 3093841 BCB02_000045 CC(=O)n1cc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C14 compound treatment 91600.0 -13600.0 -1.25 83200.0 -18400.0 -1.71 -2.0918 -0.9883 3000768 BCB02_000046 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C15 compound treatment 93200.0 -12000.0 -1.1 92000.0 -9620.0 -0.89 -1.4109 -0.9944 3093842 BCB02_000047 CCCCC(CC)C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C16 compound treatment 96400.0 -8800.0 -0.81 98800.0 -2820.0 -0.26 -0.7571 -0.8899 3093843 BCB02_000048 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C17 mock treatment 105200.0 -3.05 0.0 96800.0 -4820.0 -0.45 -0.3158 -0.7076 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C18 mock treatment 107200.0 2000.0 0.18 99200.0 -2420.0 -0.22 -0.0284 -0.0982 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C19 mock treatment 100800.0 -4400.0 -0.41 96400.0 -5220.0 -0.48 -0.6282 -0.9961 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C20 mock treatment 102400.0 -2800.0 -0.26 100400.0 -1220.0 -0.11 -0.262 -0.9311 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C21 mock treatment 106400.0 1200.0 0.11 105200.0 3580.0 0.33 0.3128 0.8936 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C22 mock treatment 108400.0 3200.0 0.29 104400.0 2780.0 0.26 0.3904 0.9979 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C23 mock treatment 106800.0 1600.0 0.15 108000.0 6380.0 0.59 0.5223 0.8566 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 C24 mock treatment 106800.0 1600.0 0.15 104800.0 3180.0 0.3 0.3126 0.9481 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D01 compound treatment 106800.0 1600.0 0.15 99200.0 -2420.0 -0.22 -0.0545 -0.2034 3000769 BCB02_000049 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D02 compound treatment 106400.0 1200.0 0.11 95600.0 -6020.0 -0.56 -0.3164 -0.5567 3093844 BCB02_000050 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D03 compound treatment 99600.0 -5600.0 -0.52 90800.0 -10800.0 -1.0 -1.0733 -0.9522 3093845 BCB02_000051 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D04 compound treatment 107200.0 2000.0 0.18 104800.0 3180.0 0.3 0.3386 0.974 3000770 BCB02_000052 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D05 compound treatment 93200.0 -12000.0 -1.1 95600.0 -6020.0 -0.56 -1.175 -0.9499 3093846 BCB02_000053 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c(C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D06 compound treatment 86400.0 -18800.0 -1.73 83200.0 -18400.0 -1.71 -2.43 -1.0 3000771 BCB02_000054 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D07 compound treatment 93600.0 -11600.0 -1.07 95600.0 -6020.0 -0.56 -1.149 -0.9542 3092586 BCB02_000055 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D08 compound treatment 78800.0 -26400.0 -2.43 71200.0 -30400.0 -2.82 -3.7108 -0.9972 3092495 BCB02_000056 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D09 compound treatment 92800.0 -12400.0 -1.14 97200.0 -4420.0 -0.41 -1.0961 -0.9043 3000772 BCB02_000057 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D10 compound treatment 79600.0 -25600.0 -2.36 79600.0 -22000.0 -2.04 -3.1082 -0.9975 3092496 BCB02_000058 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D11 compound treatment 96400.0 -8800.0 -0.81 95200.0 -6420.0 -0.59 -0.9931 -0.9885 3092497 BCB02_000059 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D12 compound treatment 68800.0 -36400.0 -3.35 72800.0 -28800.0 -2.67 -4.2564 -0.9937 3000773 BCB02_000060 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D13 compound treatment 95600.0 -9600.0 -0.88 94800.0 -6820.0 -0.63 -1.0713 -0.9865 3092498 BCB02_000061 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D14 compound treatment 79600.0 -25600.0 -2.36 82000.0 -19600.0 -1.82 -2.9509 -0.9918 3000774 BCB02_000062 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D15 compound treatment 92000.0 -13200.0 -1.21 88800.0 -12800.0 -1.19 -1.6987 -0.9999 3092499 BCB02_000063 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D16 compound treatment 69600.0 -35600.0 -3.27 60800.0 -40800.0 -3.78 -4.9909 -0.9974 3000775 BCB02_000064 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D17 mock treatment 96400.0 -8800.0 -0.81 90400.0 -11200.0 -1.04 -1.3077 -0.9924 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D18 mock treatment 101600.0 -3600.0 -0.33 95600.0 -6020.0 -0.56 -0.6286 -0.9691 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D19 mock treatment 106000.0 797.0 0.07 106400.0 4780.0 0.44 0.3654 0.813 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D20 mock treatment 94800.0 -10400.0 -0.96 97200.0 -4420.0 -0.41 -0.9661 -0.9282 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D21 mock treatment 108800.0 3600.0 0.33 100000.0 -1620.0 -0.15 0.1281 0.3526 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D22 mock treatment 110000.0 4800.0 0.44 100000.0 -1620.0 -0.15 0.2061 0.4423 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D23 mock treatment 106400.0 1200.0 0.11 104400.0 2780.0 0.26 0.2603 0.9279 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 D24 mock treatment 99200.0 -6000.0 -0.55 106800.0 5180.0 0.48 -0.0507 -0.0692 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E01 compound treatment 96400.0 -8800.0 -0.81 99200.0 -2420.0 -0.22 -0.7309 -0.87 3092500 BCB02_000065 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E02 compound treatment 100800.0 -4400.0 -0.41 93200.0 -8420.0 -0.78 -0.838 -0.9534 3000776 BCB02_000066 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E03 compound treatment 95200.0 -10000.0 -0.92 94400.0 -7220.0 -0.67 -1.1236 -0.9877 3000847 BCB02_000067 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E04 compound treatment 88800.0 -16400.0 -1.51 87200.0 -14400.0 -1.34 -2.0117 -0.9982 3000848 BCB02_000068 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E05 compound treatment 100000.0 -5200.0 -0.48 94000.0 -7620.0 -0.71 -0.8376 -0.9821 3000849 BCB02_000069 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E06 compound treatment 99200.0 -6000.0 -0.55 94800.0 -6820.0 -0.63 -0.8372 -0.9977 3000850 BCB02_000070 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E07 compound treatment 104400.0 -803.0 -0.07 98400.0 -3220.0 -0.3 -0.263 -0.8564 3000851 BCB02_000071 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E08 compound treatment 97200.0 -8000.0 -0.74 94800.0 -6820.0 -0.63 -0.9672 -0.9971 3092501 BCB02_000072 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E09 compound treatment 82000.0 -23200.0 -2.13 85200.0 -16400.0 -1.52 -2.5851 -0.9862 3000852 BCB02_000073 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E10 compound treatment 71600.0 -33600.0 -3.09 76400.0 -25200.0 -2.34 -3.8383 -0.9905 3092502 BCB02_000074 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E11 compound treatment 93200.0 -12000.0 -1.1 88400.0 -13200.0 -1.22 -1.6469 -0.9987 3092503 BCB02_000075 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E12 compound treatment 82400.0 -22800.0 -2.1 86800.0 -14800.0 -1.37 -2.4542 -0.9789 3000853 BCB02_000076 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E13 compound treatment 92400.0 -12800.0 -1.18 85600.0 -16000.0 -1.48 -1.8824 -0.9934 3092504 BCB02_000077 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E14 compound treatment 88400.0 -16800.0 -1.55 91600.0 -10000.0 -0.93 -1.7494 -0.9703 3000854 BCB02_000078 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E15 compound treatment 85200.0 -20000.0 -1.84 90000.0 -11600.0 -1.08 -2.0624 -0.9674 3092505 BCB02_000079 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E16 compound treatment 84400.0 -20800.0 -1.91 86800.0 -14800.0 -1.37 -2.3241 -0.9868 3000855 BCB02_000080 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E17 mock treatment 96800.0 -8400.0 -0.77 95200.0 -6420.0 -0.59 -0.967 -0.9916 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E18 mock treatment 104000.0 -1200.0 -0.11 97200.0 -4420.0 -0.41 -0.3677 -0.8672 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E19 mock treatment 104800.0 -403.0 -0.04 95600.0 -6020.0 -0.56 -0.4205 -0.7525 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E20 mock treatment 100400.0 -4800.0 -0.44 98400.0 -3220.0 -0.3 -0.5232 -0.9816 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E21 mock treatment 99200.0 -6000.0 -0.55 98000.0 -3620.0 -0.34 -0.6274 -0.9714 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E22 mock treatment 105600.0 397.0 0.04 106000.0 4380.0 0.41 0.3132 0.7675 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E23 mock treatment 108000.0 2800.0 0.26 102400.0 784.0 0.07 0.2333 0.8728 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 E24 mock treatment 105600.0 397.0 0.04 108800.0 7180.0 0.67 0.4967 0.7448 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F01 compound treatment 93200.0 -12000.0 -1.1 83200.0 -18400.0 -1.71 -1.9877 -0.9778 3092506 BCB02_000081 OC(COCc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F02 compound treatment 72800.0 -32400.0 -2.98 68800.0 -32800.0 -3.04 -4.2584 -0.9999 3092507 BCB02_000082 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F03 compound treatment 101200.0 -4000.0 -0.37 97200.0 -4420.0 -0.41 -0.5498 -0.9986 3000856 BCB02_000083 COc1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F04 compound treatment 73200.0 -32000.0 -2.94 75600.0 -26000.0 -2.41 -3.7867 -0.9951 3092508 BCB02_000084 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F05 compound treatment 84000.0 -21200.0 -1.95 86000.0 -15600.0 -1.45 -2.4026 -0.9892 3092509 BCB02_000085 CCCCC(O)C1C=CC2C(N1Nc3ccc(OC)cc3)C(=O)N(C4CCCCC4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F06 compound treatment 61600.0 -43600.0 -4.01 56000.0 -45600.0 -4.23 -5.8258 -0.9997 3000857 BCB02_000086 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F07 compound treatment 91600.0 -13600.0 -1.25 92800.0 -8820.0 -0.82 -1.4626 -0.9787 3092510 BCB02_000087 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F08 compound treatment 59600.0 -45600.0 -4.19 64800.0 -36800.0 -3.41 -5.3791 -0.9948 3000858 BCB02_000088 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F09 compound treatment 92000.0 -13200.0 -1.21 91200.0 -10400.0 -0.97 -1.5414 -0.9935 3092511 BCB02_000089 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F10 compound treatment 50800.0 -54400.0 -5.0 48400.0 -53200.0 -4.93 -7.0264 -1.0 3000859 BCB02_000090 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F11 compound treatment 80000.0 -25200.0 -2.32 85600.0 -16000.0 -1.48 -2.689 -0.9768 3092512 BCB02_000091 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F12 compound treatment 68000.0 -37200.0 -3.42 64400.0 -37200.0 -3.45 -4.859 -1.0 3092513 BCB02_000092 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F13 compound treatment 94400.0 -10800.0 -0.99 91200.0 -10400.0 -0.97 -1.3853 -0.9999 3000860 BCB02_000093 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F14 compound treatment 66400.0 -38800.0 -3.57 65200.0 -36400.0 -3.38 -4.9106 -0.9996 3092514 BCB02_000094 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F15 compound treatment 94000.0 -11200.0 -1.03 86800.0 -14800.0 -1.37 -1.6997 -0.99 3092515 BCB02_000095 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F16 compound treatment 67600.0 -37600.0 -3.46 69200.0 -32400.0 -3.0 -4.5704 -0.9975 3000861 BCB02_000096 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F17 mock treatment 91200.0 -14000.0 -1.29 92400.0 -9220.0 -0.85 -1.5148 -0.9801 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F18 mock treatment 88000.0 -17200.0 -1.58 92000.0 -9620.0 -0.89 -1.7492 -0.9631 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F19 mock treatment 91600.0 -13600.0 -1.25 87200.0 -14400.0 -1.34 -1.8296 -0.9995 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F20 mock treatment 97600.0 -7600.0 -0.7 94800.0 -6820.0 -0.63 -0.9412 -0.9987 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F21 mock treatment 96400.0 -8800.0 -0.81 90800.0 -10800.0 -1.0 -1.2815 -0.9944 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F22 mock treatment 99200.0 -6000.0 -0.55 98000.0 -3620.0 -0.34 -0.6274 -0.9714 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F23 mock treatment 101600.0 -3600.0 -0.33 100400.0 -1220.0 -0.11 -0.314 -0.8971 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 F24 mock treatment 104400.0 -803.0 -0.07 96800.0 -4820.0 -0.45 -0.3679 -0.8131 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G01 compound treatment 97600.0 -7600.0 -0.7 94000.0 -7620.0 -0.71 -0.9937 -1.0 3092516 BCB02_000097 CC(C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G02 compound treatment 68400.0 -36800.0 -3.39 70800.0 -30800.0 -2.86 -4.4135 -0.9964 3000862 BCB02_000098 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G03 compound treatment 77600.0 -27600.0 -2.54 85200.0 -16400.0 -1.52 -2.8713 -0.97 3092587 BCB02_000099 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G04 compound treatment 64400.0 -40800.0 -3.75 65600.0 -36000.0 -3.34 -5.0145 -0.9983 3000863 BCB02_000100 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G05 compound treatment 91200.0 -14000.0 -1.29 94800.0 -6820.0 -0.63 -1.3575 -0.9462 3092588 BCB02_000101 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G06 compound treatment 76400.0 -28800.0 -2.65 76800.0 -24800.0 -2.3 -3.4999 -0.9975 3092589 BCB02_000102 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G07 compound treatment 85600.0 -19600.0 -1.8 74000.0 -27600.0 -2.56 -3.085 -0.9853 3000864 BCB02_000103 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G08 compound treatment 75200.0 -30000.0 -2.76 79200.0 -22400.0 -2.08 -3.4206 -0.9902 3092590 BCB02_000104 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G09 compound treatment 81600.0 -23600.0 -2.17 82800.0 -18800.0 -1.74 -2.7684 -0.9941 3092591 BCB02_000105 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G10 compound treatment 77200.0 -28000.0 -2.58 77200.0 -24400.0 -2.26 -3.4216 -0.9979 3000865 BCB02_000106 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G11 compound treatment 96800.0 -8400.0 -0.77 92400.0 -9220.0 -0.85 -1.1506 -0.9988 3092592 BCB02_000107 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccn5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G12 compound treatment 80000.0 -25200.0 -2.32 74800.0 -26800.0 -2.49 -3.3968 -0.9994 3000866 BCB02_000108 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G13 compound treatment 92000.0 -13200.0 -1.21 84800.0 -16800.0 -1.56 -1.9609 -0.9924 3092593 BCB02_000109 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G14 compound treatment 74000.0 -31200.0 -2.87 67600.0 -34000.0 -3.15 -4.259 -0.9989 3000867 BCB02_000110 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G15 compound treatment 72800.0 -32400.0 -2.98 58000.0 -43600.0 -4.04 -4.9662 -0.9888 3092594 BCB02_000111 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G16 compound treatment 90400.0 -14800.0 -1.36 80000.0 -21600.0 -2.0 -2.3796 -0.9823 3092595 BCB02_000112 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G17 mock treatment 94400.0 -10800.0 -0.99 92400.0 -9220.0 -0.85 -1.3067 -0.9972 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G18 mock treatment 95600.0 -9600.0 -0.88 94000.0 -7620.0 -0.71 -1.1238 -0.9938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G19 mock treatment 96000.0 -9200.0 -0.85 96000.0 -5620.0 -0.52 -0.9666 -0.9727 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G20 mock treatment 96400.0 -8800.0 -0.81 100800.0 -816.0 -0.08 -0.626 -0.7698 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G21 mock treatment 102400.0 -2800.0 -0.26 96800.0 -4820.0 -0.45 -0.4979 -0.966 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G22 mock treatment 104400.0 -803.0 -0.07 104000.0 2380.0 0.22 0.104 0.4465 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G23 mock treatment 105600.0 397.0 0.04 110800.0 9180.0 0.85 0.6278 0.7368 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 G24 mock treatment 114000.0 8800.0 0.81 102000.0 384.0 0.04 0.5974 0.7375 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H01 compound treatment 101600.0 -3600.0 -0.33 102800.0 1180.0 0.11 -0.1567 -0.4489 3000868 BCB02_000113 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H02 compound treatment 77600.0 -27600.0 -2.54 74400.0 -27200.0 -2.52 -3.5791 -1.0 3092596 BCB02_000114 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H03 compound treatment 103600.0 -1600.0 -0.15 94000.0 -7620.0 -0.71 -0.6034 -0.8368 3092597 BCB02_000115 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H04 compound treatment 84400.0 -20800.0 -1.91 74800.0 -26800.0 -2.49 -3.1106 -0.9917 3000869 BCB02_000116 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H05 compound treatment 102400.0 -2800.0 -0.26 104000.0 2380.0 0.22 -0.026 -0.0767 3092598 BCB02_000117 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H06 compound treatment 83600.0 -21600.0 -1.99 72800.0 -28800.0 -2.67 -3.2938 -0.9894 3000870 BCB02_000118 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H07 compound treatment 102000.0 -3200.0 -0.29 94800.0 -6820.0 -0.63 -0.655 -0.9397 3000871 BCB02_000119 O=c1cccc(o1)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H08 compound treatment 82000.0 -23200.0 -2.13 81200.0 -20400.0 -1.89 -2.8473 -0.9982 3092599 BCB02_000120 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H09 compound treatment 88800.0 -16400.0 -1.51 86000.0 -15600.0 -1.45 -2.0904 -0.9998 3000872 BCB02_000121 COc1cccc(c1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H10 compound treatment 65200.0 -40000.0 -3.68 59200.0 -42400.0 -3.93 -5.3819 -0.9995 3092600 BCB02_000122 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H11 compound treatment 111200.0 6000.0 0.55 102800.0 1180.0 0.11 0.4677 0.8315 1984103 BCB02_000123 Cc1ccc(cc1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H12 compound treatment 69200.0 -36000.0 -3.31 69200.0 -32400.0 -3.0 -4.4663 -0.9988 3092601 BCB02_000124 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H13 compound treatment 89600.0 -15600.0 -1.44 92000.0 -9620.0 -0.89 -1.6451 -0.9737 3000873 BCB02_000125 Clc1cccc(c1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H14 compound treatment 95600.0 -9600.0 -0.88 91200.0 -10400.0 -0.97 -1.3073 -0.999 3000874 BCB02_000126 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H15 compound treatment 100000.0 -5200.0 -0.48 89600.0 -12000.0 -1.11 -1.1259 -0.9288 3000875 BCB02_000127 Clc1ccccc1c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H16 compound treatment 93200.0 -12000.0 -1.1 96800.0 -4820.0 -0.45 -1.0963 -0.9206 3092602 BCB02_000128 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H17 mock treatment 99200.0 -6000.0 -0.55 86800.0 -14800.0 -1.37 -1.3615 -0.9199 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H18 mock treatment 104400.0 -803.0 -0.07 95200.0 -6420.0 -0.59 -0.4727 -0.7889 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H19 mock treatment 99200.0 -6000.0 -0.55 94000.0 -7620.0 -0.71 -0.8896 -0.9926 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H20 mock treatment 102000.0 -3200.0 -0.29 96800.0 -4820.0 -0.45 -0.524 -0.9797 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H21 mock treatment 102000.0 -3200.0 -0.29 101200.0 -416.0 -0.04 -0.2356 -0.7928 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H22 mock treatment 112800.0 7600.0 0.7 100800.0 -816.0 -0.08 0.4407 0.6269 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H23 mock treatment 105200.0 -3.05 0.0 103600.0 1980.0 0.18 0.1299 0.706 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 H24 mock treatment 109200.0 4000.0 0.37 107200.0 5580.0 0.52 0.626 0.986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I01 compound treatment 104400.0 -803.0 -0.07 105200.0 3580.0 0.33 0.1827 0.5368 3092603 BCB02_000129 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccs5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I02 compound treatment 81600.0 -23600.0 -2.17 80800.0 -20800.0 -1.93 -2.8995 -0.9983 3000947 BCB02_000130 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I03 compound treatment 83600.0 -21600.0 -1.99 85200.0 -16400.0 -1.52 -2.481 -0.9913 3000948 BCB02_000131 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I04 compound treatment 76800.0 -28400.0 -2.61 78800.0 -22800.0 -2.11 -3.3428 -0.9945 3000949 BCB02_000132 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I05 compound treatment 96400.0 -8800.0 -0.81 98800.0 -2820.0 -0.26 -0.7571 -0.8899 3000950 BCB02_000133 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I06 compound treatment 63200.0 -42000.0 -3.86 67200.0 -34400.0 -3.19 -4.9877 -0.9955 3000951 BCB02_000134 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I07 compound treatment 97600.0 -7600.0 -0.7 91600.0 -10000.0 -0.93 -1.151 -0.9902 3092604 BCB02_000135 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I08 compound treatment 80400.0 -24800.0 -2.28 76400.0 -25200.0 -2.34 -3.2659 -0.9999 3000952 BCB02_000136 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I09 compound treatment 94000.0 -11200.0 -1.03 79600.0 -22000.0 -2.04 -2.1716 -0.9499 3092605 BCB02_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I10 compound treatment 87200.0 -18000.0 -1.66 79600.0 -22000.0 -2.04 -2.6139 -0.9946 3092606 BCB02_000138 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I11 compound treatment 88800.0 -16400.0 -1.51 92800.0 -8820.0 -0.82 -1.6447 -0.9585 3000953 BCB02_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I12 compound treatment 55200.0 -50000.0 -4.6 56800.0 -44800.0 -4.15 -6.1896 -0.9987 3092607 BCB02_000140 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I13 compound treatment 94800.0 -10400.0 -0.96 92000.0 -9620.0 -0.89 -1.3069 -0.9994 3092678 BCB02_000141 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I14 compound treatment 92000.0 -13200.0 -1.21 85200.0 -16400.0 -1.52 -1.9347 -0.9938 3000954 BCB02_000142 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I15 compound treatment 100000.0 -5200.0 -0.48 97600.0 -4020.0 -0.37 -0.6016 -0.9923 3092679 BCB02_000143 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I16 compound treatment 75200.0 -30000.0 -2.76 72000.0 -29600.0 -2.75 -3.8925 -1.0 3000955 BCB02_000144 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I17 mock treatment 103600.0 -1600.0 -0.15 94800.0 -6820.0 -0.63 -0.551 -0.8493 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I18 mock treatment 104800.0 -403.0 -0.04 100400.0 -1220.0 -0.11 -0.1059 -0.8927 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I19 mock treatment 101200.0 -4000.0 -0.37 102000.0 384.0 0.04 -0.2352 -0.6357 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I20 mock treatment 98000.0 -7200.0 -0.66 104800.0 3180.0 0.3 -0.2598 -0.3582 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I21 mock treatment 100800.0 -4400.0 -0.41 99600.0 -2020.0 -0.19 -0.4185 -0.9383 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I22 mock treatment 110000.0 4800.0 0.44 107200.0 5580.0 0.52 0.678 0.9968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I23 mock treatment 103200.0 -2000.0 -0.18 104800.0 3180.0 0.3 0.0784 0.2254 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 I24 mock treatment 114800.0 9600.0 0.88 111200.0 9580.0 0.89 1.2524 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J01 compound treatment 99200.0 -6000.0 -0.55 108800.0 7180.0 0.67 0.0804 0.093 3000956 BCB02_000145 CCCc1cccc(=O)o1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J02 compound treatment 108400.0 3200.0 0.29 98800.0 -2820.0 -0.26 0.0234 0.0595 3092680 BCB02_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J03 compound treatment 98800.0 -6400.0 -0.59 105600.0 3980.0 0.37 -0.1553 -0.2234 3000957 BCB02_000147 Fc1ccc(cc1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J04 compound treatment 97200.0 -8000.0 -0.74 105200.0 3580.0 0.33 -0.2856 -0.3536 3092681 BCB02_000148 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J05 compound treatment 94400.0 -10800.0 -0.99 104800.0 3180.0 0.3 -0.4939 -0.4765 3000958 BCB02_000149 O=c1cccc(o1)c2ccc(C#N)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J06 compound treatment 96000.0 -9200.0 -0.85 85200.0 -16400.0 -1.52 -1.6745 -0.9617 3000959 BCB02_000150 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J07 compound treatment 91600.0 -13600.0 -1.25 86800.0 -14800.0 -1.37 -1.8558 -0.9989 3092682 BCB02_000151 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J08 compound treatment 84400.0 -20800.0 -1.91 87600.0 -14000.0 -1.3 -2.2717 -0.9822 3092683 BCB02_000152 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J09 compound treatment 95200.0 -10000.0 -0.92 86800.0 -14800.0 -1.37 -1.6217 -0.981 3000960 BCB02_000153 FC(F)(F)c1ccccc1c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J10 compound treatment 93200.0 -12000.0 -1.1 83200.0 -18400.0 -1.71 -1.9877 -0.9778 3092684 BCB02_000154 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J11 compound treatment 124400.0 19200.0 1.77 112400.0 10800.0 1.0 1.9554 0.9637 3000961 BCB02_000155 O=c1cccc(o1)c2ccc3ccccc3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J12 compound treatment 93200.0 -12000.0 -1.1 92400.0 -9220.0 -0.85 -1.3847 -0.992 3000962 BCB02_000156 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J13 compound treatment 98400.0 -6800.0 -0.63 95200.0 -6420.0 -0.59 -0.863 -0.9997 3092685 BCB02_000157 O=c1cccc(o1)c2ccco2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J14 compound treatment 99600.0 -5600.0 -0.52 95600.0 -6020.0 -0.56 -0.7587 -0.9992 3092686 BCB02_000158 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J15 compound treatment 101600.0 -3600.0 -0.33 93200.0 -8420.0 -0.78 -0.7859 -0.9273 3000963 BCB02_000159 O=c1cccc(CCc2ccccc2)o1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J16 compound treatment 94400.0 -10800.0 -0.99 94400.0 -7220.0 -0.67 -1.1756 -0.9814 3092687 BCB02_000160 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J17 mock treatment 101600.0 -3600.0 -0.33 94400.0 -7220.0 -0.67 -0.7073 -0.9475 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J18 mock treatment 102800.0 -2400.0 -0.22 96800.0 -4820.0 -0.45 -0.4719 -0.9475 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J19 mock treatment 98400.0 -6800.0 -0.63 97200.0 -4420.0 -0.41 -0.7319 -0.9788 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J20 mock treatment 102400.0 -2800.0 -0.26 100400.0 -1220.0 -0.11 -0.262 -0.9311 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J21 mock treatment 98800.0 -6400.0 -0.59 94400.0 -7220.0 -0.67 -0.8894 -0.998 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J22 mock treatment 102400.0 -2800.0 -0.26 96800.0 -4820.0 -0.45 -0.4979 -0.966 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J23 mock treatment 106800.0 1600.0 0.15 104000.0 2380.0 0.22 0.2601 0.9803 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 J24 mock treatment 102800.0 -2400.0 -0.22 111200.0 9580.0 0.89 0.4719 0.5155 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K01 compound treatment 97200.0 -8000.0 -0.74 98400.0 -3220.0 -0.3 -0.7313 -0.9208 3000964 BCB02_000161 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K02 compound treatment 80400.0 -24800.0 -2.28 83600.0 -18000.0 -1.67 -2.794 -0.9882 3092688 BCB02_000162 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K03 compound treatment 82000.0 -23200.0 -2.13 82400.0 -19200.0 -1.78 -2.7686 -0.996 3092689 BCB02_000163 CC(C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K04 compound treatment 57600.0 -47600.0 -4.38 55600.0 -46000.0 -4.27 -6.1122 -0.9999 3000965 BCB02_000164 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K05 compound treatment 100000.0 -5200.0 -0.48 98400.0 -3220.0 -0.3 -0.5492 -0.974 3092690 BCB02_000165 CC(CC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K06 compound treatment 105600.0 397.0 0.04 104000.0 2380.0 0.22 0.1821 0.8129 3000966 BCB02_000166 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K07 compound treatment 92800.0 -12400.0 -1.14 96800.0 -4820.0 -0.45 -1.1224 -0.9161 3092691 BCB02_000167 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccs5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K08 compound treatment 72400.0 -32800.0 -3.02 69200.0 -32400.0 -3.0 -4.2582 -1.0 3092692 BCB02_000168 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K09 compound treatment 99200.0 -6000.0 -0.55 84800.0 -16800.0 -1.56 -1.4926 -0.9026 3000967 BCB02_000169 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K10 compound treatment 97200.0 -8000.0 -0.74 96400.0 -5220.0 -0.48 -0.8624 -0.9792 3092693 BCB02_000170 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K11 compound treatment 97200.0 -8000.0 -0.74 85600.0 -16000.0 -1.48 -1.5702 -0.9476 3000968 BCB02_000171 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K12 compound treatment 52800.0 -52400.0 -4.82 54000.0 -47600.0 -4.41 -6.5293 -0.999 3092694 BCB02_000172 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K13 compound treatment 92800.0 -12400.0 -1.14 94800.0 -6820.0 -0.63 -1.2534 -0.9611 3092695 BCB02_000173 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K14 compound treatment 60000.0 -45200.0 -4.16 58400.0 -43200.0 -4.01 -5.7726 -0.9998 3000969 BCB02_000174 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K15 compound treatment 88800.0 -16400.0 -1.51 83200.0 -18400.0 -1.71 -2.2739 -0.9981 3092696 BCB02_000175 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K16 compound treatment 67200.0 -38000.0 -3.5 66400.0 -35200.0 -3.26 -4.7799 -0.9994 3000970 BCB02_000176 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)N(CC)CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K17 mock treatment 97600.0 -7600.0 -0.7 94400.0 -7220.0 -0.67 -0.9674 -0.9998 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K18 mock treatment 100000.0 -5200.0 -0.48 92400.0 -9220.0 -0.85 -0.9424 -0.9625 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K19 mock treatment 101600.0 -3600.0 -0.33 101600.0 -15.6 0.0 -0.2354 -0.7102 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K20 mock treatment 96400.0 -8800.0 -0.81 98400.0 -3220.0 -0.3 -0.7833 -0.9078 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K21 mock treatment 105600.0 397.0 0.04 98000.0 -3620.0 -0.34 -0.2112 -0.6264 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K22 mock treatment 110400.0 5200.0 0.48 107600.0 5980.0 0.55 0.7303 0.9973 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K23 mock treatment 107200.0 2000.0 0.18 108800.0 7180.0 0.67 0.6008 0.8697 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 K24 mock treatment 102400.0 -2800.0 -0.26 111200.0 9580.0 0.89 0.4459 0.482 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L01 compound treatment 107200.0 2000.0 0.18 98000.0 -3620.0 -0.34 -0.1071 -0.2802 3000971 BCB02_000177 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L02 compound treatment 98000.0 -7200.0 -0.66 87600.0 -14000.0 -1.3 -1.3871 -0.9512 3092697 BCB02_000178 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L03 compound treatment 100000.0 -5200.0 -0.48 98800.0 -2820.0 -0.26 -0.523 -0.9593 3000972 BCB02_000179 O=c1cccc(/C=C/c2ccccc2)o1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L04 compound treatment 107600.0 2400.0 0.22 94800.0 -6820.0 -0.63 -0.2908 -0.4346 3092698 BCB02_000180 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L05 compound treatment 101200.0 -4000.0 -0.37 103200.0 1580.0 0.15 -0.1565 -0.3948 3000973 BCB02_000181 O=c1cccc(o1)c2cccc3ccccc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L06 compound treatment 108800.0 3600.0 0.33 99200.0 -2420.0 -0.22 0.0756 0.1893 3092699 BCB02_000182 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L07 compound treatment 106000.0 797.0 0.07 105200.0 3580.0 0.33 0.2868 0.8429 3000974 BCB02_000183 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L08 compound treatment 104800.0 -403.0 -0.04 95600.0 -6020.0 -0.56 -0.4205 -0.7525 3092700 BCB02_000184 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L09 compound treatment 81600.0 -23600.0 -2.17 77600.0 -24000.0 -2.23 -3.1092 -0.9999 3092701 BCB02_000185 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L10 compound treatment 95200.0 -10000.0 -0.92 87600.0 -14000.0 -1.3 -1.5692 -0.9857 3000975 BCB02_000186 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L11 compound treatment 100800.0 -4400.0 -0.41 88400.0 -13200.0 -1.22 -1.1526 -0.8933 3092771 BCB02_000187 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L12 compound treatment 96800.0 -8400.0 -0.77 86400.0 -15200.0 -1.41 -1.5438 -0.9599 3000976 BCB02_000188 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L13 compound treatment 100800.0 -4400.0 -0.41 100400.0 -1220.0 -0.11 -0.3661 -0.8708 3092772 BCB02_000189 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L14 compound treatment 99600.0 -5600.0 -0.52 93600.0 -8020.0 -0.74 -0.8898 -0.984 3092773 BCB02_000190 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L15 compound treatment 89200.0 -16000.0 -1.47 80800.0 -20800.0 -1.93 -2.4052 -0.9911 3000977 BCB02_000191 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L16 compound treatment 96800.0 -8400.0 -0.77 93200.0 -8420.0 -0.78 -1.0981 -1.0 3092774 BCB02_000192 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L17 mock treatment 100000.0 -5200.0 -0.48 92000.0 -9620.0 -0.89 -0.9686 -0.9575 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L18 mock treatment 104400.0 -803.0 -0.07 96800.0 -4820.0 -0.45 -0.3679 -0.8131 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L19 mock treatment 98000.0 -7200.0 -0.66 106000.0 4380.0 0.41 -0.1811 -0.2331 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L20 mock treatment 106400.0 1200.0 0.11 98400.0 -3220.0 -0.3 -0.1329 -0.4183 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L21 mock treatment 106000.0 797.0 0.07 98000.0 -3620.0 -0.34 -0.1851 -0.5397 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L22 mock treatment 108000.0 2800.0 0.26 101200.0 -416.0 -0.04 0.1547 0.5946 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L23 mock treatment 112400.0 7200.0 0.66 102000.0 384.0 0.04 0.4933 0.7441 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 L24 mock treatment 106400.0 1200.0 0.11 110000.0 8380.0 0.78 0.6274 0.7993 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M01 compound treatment 90800.0 -14400.0 -1.32 80400.0 -21200.0 -1.97 -2.3273 -0.9815 3000978 BCB02_000193 CC1(C)[C@H]2C[C@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M02 compound treatment 93200.0 -12000.0 -1.1 83600.0 -18000.0 -1.67 -1.9615 -0.9798 3001047 BCB02_000194 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M03 compound treatment 102400.0 -2800.0 -0.26 87600.0 -14000.0 -1.3 -1.1009 -0.8312 3092775 BCB02_000195 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M04 compound treatment 88000.0 -17200.0 -1.58 86400.0 -15200.0 -1.41 -2.1162 -0.9984 3001048 BCB02_000196 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M05 compound treatment 88800.0 -16400.0 -1.51 91600.0 -10000.0 -0.93 -1.7233 -0.9728 3092776 BCB02_000197 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)[N+](=O)[O-])C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M06 compound treatment 77600.0 -27600.0 -2.54 79600.0 -22000.0 -2.04 -3.2383 -0.9941 3001049 BCB02_000198 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M07 compound treatment 90000.0 -15200.0 -1.4 84800.0 -16800.0 -1.56 -2.091 -0.9985 3092777 BCB02_000199 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M08 compound treatment 76400.0 -28800.0 -2.65 76000.0 -25600.0 -2.37 -3.5523 -0.9985 3092778 BCB02_000200 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M09 compound treatment 95600.0 -9600.0 -0.88 88800.0 -12800.0 -1.19 -1.4646 -0.9894 3001050 BCB02_000201 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M10 compound treatment 57200.0 -48000.0 -4.42 57600.0 -44000.0 -4.08 -6.0071 -0.9992 3001168 BCB02_000202 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M11 compound treatment 91600.0 -13600.0 -1.25 82800.0 -18800.0 -1.74 -2.118 -0.9867 3092779 BCB02_000203 COc1ccc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M12 compound treatment 76800.0 -28400.0 -2.61 73200.0 -28400.0 -2.63 -3.7098 -1.0 3092780 BCB02_000204 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M13 compound treatment 89600.0 -15600.0 -1.44 90800.0 -10800.0 -1.0 -1.7237 -0.9846 3001169 BCB02_000205 COc1ccc(NN2C3C(C=CC2C(O)C4=CC[C@H](CC4)C(=C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M14 compound treatment 93600.0 -11600.0 -1.07 86800.0 -14800.0 -1.37 -1.7257 -0.9922 3092781 BCB02_000206 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M15 compound treatment 107200.0 2000.0 0.18 106400.0 4780.0 0.44 0.4435 0.9239 3001170 BCB02_000207 COc1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M16 mock treatment 106800.0 1600.0 0.15 100400.0 -1220.0 -0.11 0.0242 0.1307 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M17 mock treatment 104400.0 -803.0 -0.07 94400.0 -7220.0 -0.67 -0.5252 -0.7805 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M18 mock treatment 99200.0 -6000.0 -0.55 97200.0 -4420.0 -0.41 -0.6799 -0.9891 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M19 mock treatment 98800.0 -6400.0 -0.59 98800.0 -2820.0 -0.26 -0.601 -0.9329 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M20 mock treatment 100800.0 -4400.0 -0.41 101200.0 -416.0 -0.04 -0.3136 -0.7709 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M21 mock treatment 106000.0 797.0 0.07 96000.0 -5620.0 -0.52 -0.3162 -0.6016 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M22 mock treatment 109200.0 4000.0 0.37 104800.0 3180.0 0.3 0.4687 0.9941 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M23 mock treatment 112800.0 7600.0 0.7 111200.0 9580.0 0.89 1.1223 0.9929 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 M24 mock treatment 111200.0 6000.0 0.55 114800.0 13200.0 1.22 1.2542 0.9354 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N01 compound treatment 98800.0 -6400.0 -0.59 92400.0 -9220.0 -0.85 -1.0205 -0.9835 3092782 BCB02_000208 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N02 compound treatment 102400.0 -2800.0 -0.26 101200.0 -416.0 -0.04 -0.2096 -0.8038 3092783 BCB02_000209 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N03 compound treatment 102400.0 -2800.0 -0.26 101600.0 -15.6 0.0 -0.1833 -0.7111 3001171 BCB02_000210 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N04 compound treatment 110400.0 5200.0 0.48 103200.0 1580.0 0.15 0.4419 0.8836 3092784 BCB02_000211 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N05 compound treatment 117200.0 12000.0 1.1 109200.0 7580.0 0.7 1.2774 0.9763 3001172 BCB02_000212 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N06 compound treatment 99200.0 -6000.0 -0.55 100000.0 -1620.0 -0.15 -0.4963 -0.8675 3092785 BCB02_000213 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N07 compound treatment 112400.0 7200.0 0.66 96800.0 -4820.0 -0.45 0.1525 0.191 3092786 BCB02_000214 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N08 compound treatment 92400.0 -12800.0 -1.18 91600.0 -10000.0 -0.93 -1.4892 -0.9931 3001173 BCB02_000215 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N09 compound treatment 57600.0 -47600.0 -4.38 55200.0 -46400.0 -4.3 -6.1384 -1.0 3092787 BCB02_000216 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N10 compound treatment 102800.0 -2400.0 -0.22 100400.0 -1220.0 -0.11 -0.236 -0.9511 3001174 BCB02_000217 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N11 compound treatment 92400.0 -12800.0 -1.18 90800.0 -10800.0 -1.0 -1.5416 -0.9968 3092788 BCB02_000218 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N12 compound treatment 101200.0 -4000.0 -0.37 90400.0 -11200.0 -1.04 -0.9955 -0.9026 3092789 BCB02_000219 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N13 compound treatment 77200.0 -28000.0 -2.58 72400.0 -29200.0 -2.71 -3.7362 -0.9997 3001175 BCB02_000220 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N14 compound treatment 102400.0 -2800.0 -0.26 96000.0 -5620.0 -0.52 -0.5504 -0.9475 3092790 BCB02_000221 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N15 compound treatment 99600.0 -5600.0 -0.52 101600.0 -15.6 0.0 -0.3655 -0.7091 3001176 BCB02_000222 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N16 mock treatment 110400.0 5200.0 0.48 103600.0 1980.0 0.18 0.4681 0.9139 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N17 mock treatment 104800.0 -403.0 -0.04 107600.0 5980.0 0.55 0.366 0.6584 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N18 mock treatment 105200.0 -3.05 0.0 104000.0 2380.0 0.22 0.1561 0.7062 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N19 mock treatment 103200.0 -2000.0 -0.18 104000.0 2380.0 0.22 0.026 0.0903 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N20 mock treatment 114000.0 8800.0 0.81 103200.0 1580.0 0.15 0.676 0.822 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N21 mock treatment 105200.0 -3.05 0.0 100800.0 -816.0 -0.08 -0.0537 -0.7097 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N22 mock treatment 117200.0 12000.0 1.1 112400.0 10800.0 1.0 1.4871 0.9988 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N23 mock treatment 113600.0 8400.0 0.77 113600.0 12000.0 1.11 1.3316 0.9842 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 N24 mock treatment 108800.0 3600.0 0.33 105200.0 3580.0 0.33 0.4689 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O01 compound treatment 110400.0 5200.0 0.48 93600.0 -8020.0 -0.74 -0.1873 -0.212 3092791 BCB02_000223 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O02 compound treatment 112800.0 7600.0 0.7 107600.0 5980.0 0.55 0.8864 0.9935 3001177 BCB02_000224 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O03 compound treatment 98000.0 -7200.0 -0.66 100800.0 -816.0 -0.08 -0.522 -0.7827 3092792 BCB02_000225 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)c(OCc5ccccc5)c4)C(=O)N(C6CCCCC6)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O04 compound treatment 118000.0 12800.0 1.18 122800.0 21200.0 1.96 2.2208 0.97 3001178 BCB02_000226 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O05 compound treatment 115600.0 10400.0 0.96 114400.0 12800.0 1.18 1.5142 0.9943 3092860 BCB02_000227 COc1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O06 compound treatment 83600.0 -21600.0 -1.99 84400.0 -17200.0 -1.6 -2.5335 -0.9941 3001179 BCB02_000228 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O07 compound treatment 109200.0 4000.0 0.37 100400.0 -1220.0 -0.11 0.1803 0.4689 3092861 BCB02_000229 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O08 compound treatment 85600.0 -19600.0 -1.8 86800.0 -14800.0 -1.37 -2.2461 -0.991 3001245 BCB02_000230 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O09 compound treatment 86800.0 -18400.0 -1.69 84000.0 -17600.0 -1.63 -2.3515 -0.9998 3092862 BCB02_000231 COc1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O10 compound treatment 68800.0 -36400.0 -3.35 68000.0 -33600.0 -3.12 -4.571 -0.9994 3001246 BCB02_000232 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O11 compound treatment 93200.0 -12000.0 -1.1 88400.0 -13200.0 -1.22 -1.6469 -0.9987 3092863 BCB02_000233 Cc1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C5CCCCC5)C3=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O12 compound treatment 146000.0 40800.0 3.75 143600.0 42000.0 3.89 5.4053 0.9998 3001247 BCB02_000234 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O13 compound treatment 106400.0 1200.0 0.11 105200.0 3580.0 0.33 0.3128 0.8936 3092864 BCB02_000235 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O14 compound treatment 110000.0 4800.0 0.44 106000.0 4380.0 0.41 0.5994 0.9992 3001248 BCB02_000236 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O15 compound treatment 102400.0 -2800.0 -0.26 108000.0 6380.0 0.59 0.2361 0.3658 3092865 BCB02_000237 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O16 mock treatment 106400.0 1200.0 0.11 102000.0 384.0 0.04 0.103 0.8905 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O17 mock treatment 106000.0 797.0 0.07 99200.0 -2420.0 -0.22 -0.1065 -0.452 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O18 mock treatment 114400.0 9200.0 0.85 99600.0 -2020.0 -0.19 0.4661 0.538 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O19 mock treatment 111200.0 6000.0 0.55 107600.0 5980.0 0.55 0.7823 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O20 mock treatment 99600.0 -5600.0 -0.52 102000.0 384.0 0.04 -0.3392 -0.6567 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O21 mock treatment 115200.0 10000.0 0.92 106800.0 5180.0 0.48 0.99 0.9542 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O22 mock treatment 104800.0 -403.0 -0.04 107600.0 5980.0 0.55 0.366 0.6584 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O23 mock treatment 106800.0 1600.0 0.15 109200.0 7580.0 0.7 0.601 0.8368 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 O24 mock treatment 114800.0 9600.0 0.88 118000.0 16400.0 1.52 1.6981 0.9667 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P01 compound treatment 104400.0 -803.0 -0.07 93600.0 -8020.0 -0.74 -0.5776 -0.7736 3001249 BCB02_000238 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P02 compound treatment 106000.0 797.0 0.07 104800.0 3180.0 0.3 0.2605 0.8567 3092866 BCB02_000239 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P03 compound treatment 106000.0 797.0 0.07 98400.0 -3220.0 -0.3 -0.1589 -0.5178 3001250 BCB02_000240 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P04 compound treatment 84400.0 -20800.0 -1.91 75200.0 -26400.0 -2.45 -3.0844 -0.9926 3092867 BCB02_000241 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P05 compound treatment 102800.0 -2400.0 -0.22 100400.0 -1220.0 -0.11 -0.236 -0.9511 3001251 BCB02_000242 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P06 compound treatment 81200.0 -24000.0 -2.21 84000.0 -17600.0 -1.63 -2.7158 -0.989 3092868 BCB02_000243 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P07 compound treatment 108000.0 2800.0 0.26 98400.0 -3220.0 -0.3 -0.0288 -0.0732 3001252 BCB02_000244 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P08 compound treatment 113600.0 8400.0 0.77 104800.0 3180.0 0.3 0.7549 0.9129 3092869 BCB02_000245 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P09 compound treatment 88800.0 -16400.0 -1.51 78000.0 -23600.0 -2.19 -2.6147 -0.9835 3001253 BCB02_000246 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P10 compound treatment 86000.0 -19200.0 -1.77 68800.0 -32800.0 -3.04 -3.3998 -0.9666 3092870 BCB02_000247 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P11 compound treatment 110000.0 4800.0 0.44 103600.0 1980.0 0.18 0.4421 0.9247 3001254 BCB02_000248 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P12 compound treatment 90800.0 -14400.0 -1.32 96400.0 -5220.0 -0.48 -1.2787 -0.9067 3092871 BCB02_000249 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P13 compound treatment 99200.0 -6000.0 -0.55 100800.0 -816.0 -0.08 -0.4439 -0.7965 3001255 BCB02_000250 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P14 compound treatment 108000.0 2800.0 0.26 107200.0 5580.0 0.52 0.5479 0.9479 3092774 BCB02_000251 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P15 compound treatment 105200.0 -3.05 0.0 101600.0 -15.6 0.0 -0.0012 -0.8288 3092872 BCB02_000252 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P16 mock treatment 108800.0 3600.0 0.33 106800.0 5180.0 0.48 0.5737 0.9834 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P17 mock treatment 113200.0 8000.0 0.74 98800.0 -2820.0 -0.26 0.3356 0.43 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P18 mock treatment 116000.0 10800.0 0.99 101200.0 -416.0 -0.04 0.675 0.6792 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P19 mock treatment 109200.0 4000.0 0.37 112000.0 10400.0 0.96 0.9406 0.9129 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P20 mock treatment 116800.0 11600.0 1.07 117200.0 15600.0 1.44 1.7757 0.9889 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P21 mock treatment 112800.0 7600.0 0.7 112800.0 11200.0 1.04 1.2272 0.9816 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P22 mock treatment 116000.0 10800.0 0.99 107600.0 5980.0 0.55 1.0945 0.9621 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P23 mock treatment 108400.0 3200.0 0.29 115200.0 13600.0 1.26 1.0983 0.8494 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2088 P24 mock treatment 112000.0 6800.0 0.63 103600.0 1980.0 0.18 0.5722 0.8779 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A01 compound treatment 103600.0 2630.0 0.24 100800.0 1230.0 0.11 0.2515 0.9405 3220649 PK04_107001 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A02 compound treatment 88400.0 -12600.0 -1.16 94800.0 -4770.0 -0.44 -1.1304 -0.9132 3188507 PK04_107002 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A03 compound treatment 101600.0 631.0 0.06 103200.0 3630.0 0.34 0.2787 0.8172 3220651 PK04_107003 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A04 compound treatment 107200.0 6230.0 0.57 100400.0 825.0 0.08 0.4594 0.7944 3070126 PK04_107004 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A05 compound treatment 99600.0 -1370.0 -0.13 105200.0 5630.0 0.52 0.2797 0.5214 3220653 PK04_107005 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A06 compound treatment 109600.0 8630.0 0.79 112800.0 13200.0 1.23 1.4282 0.9779 3070127 PK04_107006 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A07 compound treatment 109200.0 8230.0 0.76 97600.0 -1970.0 -0.18 0.406 0.5212 3220655 PK04_107007 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A08 compound treatment 70800.0 -30200.0 -2.78 71200.0 -28400.0 -2.63 -3.822 -0.9996 3070128 PK04_107008 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A09 compound treatment 91200.0 -9770.0 -0.9 96000.0 -3570.0 -0.33 -0.8697 -0.9081 3220657 PK04_107009 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A10 compound treatment 104000.0 3030.0 0.28 102800.0 3230.0 0.3 0.4086 0.9994 3070129 PK04_107010 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A11 compound treatment 97200.0 -3770.0 -0.35 92000.0 -7570.0 -0.7 -0.7416 -0.9471 3220659 PK04_107011 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A12 compound treatment 51200.0 -49800.0 -4.58 80000.0 -19600.0 -1.81 -4.52 -0.9179 3188513 PK04_107012 CCCCCCc1nc(CCCc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)cc4CO[Si](C(C)C)(C(C)C)c41 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A13 mock treatment 96800.0 -4170.0 -0.38 103600.0 4030.0 0.37 -0.0073 -0.0137 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A14 mock treatment 108800.0 7830.0 0.72 98400.0 -1170.0 -0.11 0.4324 0.5935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A15 compound treatment 104000.0 3030.0 0.28 94000.0 -5570.0 -0.52 -0.1682 -0.2865 3220661 PK04_107013 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A16 compound treatment 66000.0 -35000.0 -3.22 73600.0 -26000.0 -2.41 -3.9769 -0.9898 3188514 PK04_107014 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A17 compound treatment 99200.0 -1770.0 -0.16 96800.0 -2770.0 -0.26 -0.2969 -0.9756 3220663 PK04_107015 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3ccccc3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A18 compound treatment 100000.0 -969.0 -0.09 96800.0 -2770.0 -0.26 -0.2449 -0.8996 3070178 PK04_107016 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A19 compound treatment 104800.0 3830.0 0.35 102000.0 2430.0 0.22 0.4082 0.9764 3220665 PK04_107017 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A20 compound treatment 92800.0 -8170.0 -0.75 92800.0 -6770.0 -0.63 -0.9753 -0.996 3070179 PK04_107018 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A21 compound treatment 98400.0 -2570.0 -0.24 108400.0 8830.0 0.82 0.4114 0.4831 3220667 PK04_107019 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A22 compound treatment 97600.0 -3370.0 -0.31 94800.0 -4770.0 -0.44 -0.532 -0.9848 3070180 PK04_107020 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A23 compound treatment 108000.0 7030.0 0.65 105200.0 5630.0 0.52 0.826 0.9943 3220669 PK04_107021 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 A24 compound treatment 102400.0 1430.0 0.13 104400.0 4830.0 0.45 0.4094 0.878 3070181 PK04_107022 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B01 compound treatment 100400.0 -569.0 -0.05 94000.0 -5570.0 -0.52 -0.4024 -0.7747 3188518 PK04_107023 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B02 compound treatment 108400.0 7430.0 0.68 110000.0 10400.0 0.97 1.1666 0.9856 3188519 PK04_107024 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B03 compound treatment 107200.0 6230.0 0.57 100400.0 825.0 0.08 0.4594 0.7944 3070182 PK04_107025 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B04 compound treatment 100000.0 -969.0 -0.09 98800.0 -775.0 -0.07 -0.1138 -0.9943 3188520 PK04_107026 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B05 compound treatment 102000.0 1030.0 0.09 93200.0 -6370.0 -0.59 -0.3507 -0.5861 3188521 PK04_107027 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B06 compound treatment 104800.0 3830.0 0.35 98000.0 -1570.0 -0.15 0.146 0.3827 3070183 PK04_107028 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B07 compound treatment 105200.0 4230.0 0.39 99200.0 -375.0 -0.03 0.2507 0.6415 3188640 PK04_107029 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B08 compound treatment 95600.0 -5370.0 -0.49 89600.0 -9970.0 -0.92 -1.003 -0.9569 3188641 PK04_107030 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B09 compound treatment 91600.0 -9370.0 -0.86 96000.0 -3570.0 -0.33 -0.8437 -0.9138 3070184 PK04_107031 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B10 compound treatment 99600.0 -1370.0 -0.13 101600.0 2030.0 0.19 0.0437 0.1934 3188642 PK04_107032 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B11 compound treatment 100800.0 -169.0 -0.02 98000.0 -1570.0 -0.15 -0.1142 -0.7779 3070185 PK04_107033 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B12 compound treatment 97600.0 -3370.0 -0.31 92400.0 -7170.0 -0.67 -0.6893 -0.9396 3188643 PK04_107034 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B13 mock treatment 108000.0 7030.0 0.65 112400.0 12800.0 1.19 1.2979 0.9591 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B14 mock treatment 103200.0 2230.0 0.21 106000.0 6430.0 0.6 0.5663 0.8989 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B15 compound treatment 99600.0 -1370.0 -0.13 96400.0 -3170.0 -0.29 -0.2971 -0.9283 3188644 PK04_107035 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B16 compound treatment 98000.0 -2970.0 -0.27 93600.0 -5970.0 -0.55 -0.5847 -0.9469 3070186 PK04_107036 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B17 compound treatment 92000.0 -8970.0 -0.82 104400.0 4830.0 0.45 -0.2671 -0.2846 3188645 PK04_107037 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B18 compound treatment 100400.0 -569.0 -0.05 105600.0 6030.0 0.56 0.3579 0.6381 3188646 PK04_107038 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B19 compound treatment 95600.0 -5370.0 -0.49 105200.0 5630.0 0.52 0.0195 0.0272 3070187 PK04_107039 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B20 compound treatment 102400.0 1430.0 0.13 102000.0 2430.0 0.22 0.2521 0.9675 3188647 PK04_107040 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B21 compound treatment 107600.0 6630.0 0.61 108000.0 8430.0 0.78 0.9835 0.9925 3188648 PK04_107041 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B22 compound treatment 102000.0 1030.0 0.09 96000.0 -3570.0 -0.33 -0.1672 -0.4852 3070188 PK04_107042 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B23 compound treatment 108400.0 7430.0 0.68 114000.0 14400.0 1.34 1.4288 0.9515 3188649 PK04_107043 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 B24 compound treatment 96400.0 -4570.0 -0.42 100000.0 425.0 0.04 -0.2693 -0.638 3188650 PK04_107044 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C01 compound treatment 104400.0 3430.0 0.32 98400.0 -1170.0 -0.11 0.1462 0.4379 3414054 PK04_107045 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C02 compound treatment 110800.0 9830.0 0.9 98000.0 -1570.0 -0.15 0.5362 0.5854 3188651 PK04_107046 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C03 compound treatment 99600.0 -1370.0 -0.13 97200.0 -2370.0 -0.22 -0.2447 -0.9649 3414055 PK04_107047 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C04 compound treatment 100800.0 -169.0 -0.02 100800.0 1230.0 0.11 0.0693 0.6049 3070235 PK04_107048 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C05 compound treatment 98000.0 -2970.0 -0.27 92000.0 -7570.0 -0.7 -0.6895 -0.9153 3414056 PK04_107049 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C06 compound treatment 92800.0 -8170.0 -0.75 98800.0 -775.0 -0.07 -0.5821 -0.7712 3070236 PK04_107050 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C07 compound treatment 99200.0 -1770.0 -0.16 93600.0 -5970.0 -0.55 -0.5066 -0.8778 3414057 PK04_107051 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C08 compound treatment 72800.0 -28200.0 -2.59 78000.0 -21600.0 -2.0 -3.2462 -0.9918 3188655 PK04_107052 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C09 compound treatment 95200.0 -5770.0 -0.53 97600.0 -1970.0 -0.18 -0.5046 -0.899 3220705 PK04_107053 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C10 compound treatment 106800.0 5830.0 0.54 102800.0 3230.0 0.3 0.5907 0.9619 3188656 PK04_107054 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C11 mock treatment 101200.0 231.0 0.02 100000.0 425.0 0.04 0.0429 0.9581 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C12 mock treatment 95200.0 -5770.0 -0.53 95200.0 -4370.0 -0.41 -0.6619 -0.9912 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C13 compound treatment 100000.0 -969.0 -0.09 97200.0 -2370.0 -0.22 -0.2186 -0.9208 3220708 PK04_107055 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C14 compound treatment 83600.0 -17400.0 -1.6 87200.0 -12400.0 -1.15 -1.9408 -0.9868 3188772 PK04_107056 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C15 mock treatment 98800.0 -2170.0 -0.2 98800.0 -775.0 -0.07 -0.1918 -0.9048 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C16 mock treatment 105600.0 4630.0 0.43 95600.0 -3970.0 -0.37 0.0407 0.0723 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C17 compound treatment 104800.0 3830.0 0.35 106800.0 7230.0 0.67 0.7228 0.955 3220711 PK04_107057 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C18 compound treatment 101600.0 631.0 0.06 97200.0 -2370.0 -0.22 -0.1146 -0.5033 3070242 PK04_107058 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C19 compound treatment 106000.0 5030.0 0.46 105200.0 5630.0 0.52 0.6959 0.9982 3220713 PK04_107059 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C20 compound treatment 98400.0 -2570.0 -0.24 106800.0 7230.0 0.67 0.3065 0.4316 3070245 PK04_107060 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C21 compound treatment 110000.0 9030.0 0.83 106800.0 7230.0 0.67 1.061 0.9943 3220715 PK04_107061 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C22 compound treatment 99200.0 -1770.0 -0.16 100800.0 1230.0 0.11 -0.0347 -0.175 3070527 PK04_107062 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C23 compound treatment 106400.0 5430.0 0.5 114800.0 15200.0 1.41 1.3512 0.9025 3220717 PK04_107063 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 C24 compound treatment 94000.0 -6970.0 -0.64 104800.0 5230.0 0.48 -0.1108 -0.1379 3070530 PK04_107064 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D01 compound treatment 96400.0 -4570.0 -0.42 92800.0 -6770.0 -0.63 -0.7412 -0.9809 3188777 PK04_107065 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D02 compound treatment 99600.0 -1370.0 -0.13 90800.0 -8770.0 -0.81 -0.6641 -0.807 3188778 PK04_107066 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D03 compound treatment 86800.0 -14200.0 -1.3 93600.0 -5970.0 -0.55 -1.3132 -0.9273 3070575 PK04_107067 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D04 compound treatment 94800.0 -6170.0 -0.57 98800.0 -775.0 -0.07 -0.452 -0.7903 3188779 PK04_107068 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D05 compound treatment 87600.0 -13400.0 -1.23 94800.0 -4770.0 -0.44 -1.1825 -0.9048 3188780 PK04_107069 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D06 compound treatment 88400.0 -12600.0 -1.16 95200.0 -4370.0 -0.41 -1.1042 -0.9013 3070579 PK04_107070 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D07 compound treatment 92400.0 -8570.0 -0.79 90400.0 -9170.0 -0.85 -1.1587 -0.9993 3188781 PK04_107071 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D08 compound treatment 96400.0 -4570.0 -0.42 84000.0 -15600.0 -1.44 -1.318 -0.8766 3188782 PK04_107072 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D09 compound treatment 90000.0 -11000.0 -1.01 88400.0 -11200.0 -1.04 -1.4458 -0.9999 3188783 PK04_107073 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D10 compound treatment 92800.0 -8170.0 -0.75 89200.0 -10400.0 -0.96 -1.2113 -0.9926 3070632 PK04_107074 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D11 mock treatment 99200.0 -1770.0 -0.16 100400.0 825.0 0.08 -0.0609 -0.339 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D12 mock treatment 100000.0 -969.0 -0.09 97200.0 -2370.0 -0.22 -0.2186 -0.9208 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D13 compound treatment 92000.0 -8970.0 -0.82 92800.0 -6770.0 -0.63 -1.0274 -0.9909 3188784 PK04_107075 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D14 compound treatment 86400.0 -14600.0 -1.34 89200.0 -10400.0 -0.96 -1.6276 -0.9867 3188785 PK04_107076 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D15 mock treatment 94400.0 -6570.0 -0.6 96800.0 -2770.0 -0.26 -0.6091 -0.9276 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D16 mock treatment 89600.0 -11400.0 -1.05 98400.0 -1170.0 -0.11 -0.8164 -0.7765 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D17 compound treatment 95600.0 -5370.0 -0.49 97200.0 -2370.0 -0.22 -0.5048 -0.9337 3070637 PK04_107077 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D18 compound treatment 84800.0 -16200.0 -1.49 85200.0 -14400.0 -1.33 -1.9938 -0.9985 3188786 PK04_107078 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D19 compound treatment 86000.0 -15000.0 -1.38 91200.0 -8370.0 -0.78 -1.5225 -0.9632 3188787 PK04_107079 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D20 compound treatment 89200.0 -11800.0 -1.08 88000.0 -11600.0 -1.07 -1.5241 -1.0 3070641 PK04_107080 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D21 compound treatment 92000.0 -8970.0 -0.82 98400.0 -1170.0 -0.11 -0.6603 -0.7935 3188905 PK04_107081 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D22 compound treatment 86400.0 -14600.0 -1.34 100400.0 825.0 0.08 -0.8935 -0.6657 3188906 PK04_107082 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D23 compound treatment 102000.0 1030.0 0.09 100800.0 1230.0 0.11 0.1474 0.996 3070684 PK04_107083 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 D24 compound treatment 92800.0 -8170.0 -0.75 97600.0 -1970.0 -0.18 -0.6607 -0.8544 3188907 PK04_107084 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E01 mock treatment 107600.0 6630.0 0.61 104400.0 4830.0 0.45 0.7476 0.9884 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E02 mock treatment 102400.0 1430.0 0.13 98000.0 -1570.0 -0.15 -0.0101 -0.0514 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E03 compound treatment 102800.0 1830.0 0.17 93600.0 -5970.0 -0.55 -0.2725 -0.4707 3220739 PK04_107085 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E04 compound treatment 102000.0 1030.0 0.09 91200.0 -8370.0 -0.78 -0.4818 -0.6161 3070690 PK04_107086 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E05 compound treatment 102000.0 1030.0 0.09 94800.0 -4770.0 -0.44 -0.2459 -0.5432 3220741 PK04_107087 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E06 compound treatment 84000.0 -17000.0 -1.56 88400.0 -11200.0 -1.04 -1.8361 -0.9802 3070694 PK04_107088 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E07 compound treatment 98800.0 -2170.0 -0.2 98800.0 -775.0 -0.07 -0.1918 -0.9048 3220743 PK04_107089 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E08 compound treatment 75600.0 -25400.0 -2.33 78400.0 -21200.0 -1.96 -3.0379 -0.9963 3188910 PK04_107090 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E09 mock treatment 92000.0 -8970.0 -0.82 98000.0 -1570.0 -0.15 -0.6866 -0.8195 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E10 mock treatment 99200.0 -1770.0 -0.16 98000.0 -1570.0 -0.15 -0.2182 -0.9985 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E11 compound treatment 95200.0 -5770.0 -0.53 95200.0 -4370.0 -0.41 -0.6619 -0.9912 3188911 PK04_107091 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E12 compound treatment 93200.0 -7770.0 -0.71 93600.0 -5970.0 -0.55 -0.8969 -0.9921 3070742 PK04_107092 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E13 compound treatment 90400.0 -10600.0 -0.97 94000.0 -5570.0 -0.52 -1.0528 -0.9563 3188912 PK04_107093 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E14 compound treatment 92400.0 -8570.0 -0.79 88000.0 -11600.0 -1.07 -1.316 -0.9885 3070746 PK04_107094 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E15 compound treatment 96400.0 -4570.0 -0.42 93600.0 -5970.0 -0.55 -0.6888 -0.9907 3188913 PK04_107095 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E16 compound treatment 81600.0 -19400.0 -1.78 83200.0 -16400.0 -1.52 -2.333 -0.9968 3070750 PK04_107096 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E17 mock treatment 94400.0 -6570.0 -0.6 96400.0 -3170.0 -0.29 -0.6353 -0.9453 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E18 mock treatment 98000.0 -2970.0 -0.27 97200.0 -2370.0 -0.22 -0.3487 -0.9943 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E19 compound treatment 98000.0 -2970.0 -0.27 98400.0 -1170.0 -0.11 -0.2701 -0.9187 3220747 PK04_107097 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E20 compound treatment 86000.0 -15000.0 -1.38 84800.0 -14800.0 -1.37 -1.942 -1.0 3188915 PK04_107098 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E21 compound treatment 98800.0 -2170.0 -0.2 107200.0 7630.0 0.71 0.3587 0.4884 3220749 PK04_107099 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E22 compound treatment 96000.0 -4970.0 -0.46 101600.0 2030.0 0.19 -0.1904 -0.3854 3070803 PK04_107100 CC(C)[Si](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)(C#Cc3ccc(Oc4ccccc4)cc3)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E23 compound treatment 106800.0 5830.0 0.54 106000.0 6430.0 0.6 0.8004 0.9986 3220751 PK04_107101 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 E24 compound treatment 108800.0 7830.0 0.72 102400.0 2830.0 0.26 0.6945 0.9062 3070808 PK04_107102 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F01 mock treatment 102000.0 1030.0 0.09 101600.0 2030.0 0.19 0.1998 0.95 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F02 mock treatment 104000.0 3030.0 0.28 104400.0 4830.0 0.45 0.5134 0.9741 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F03 compound treatment 89600.0 -11400.0 -1.05 96400.0 -3170.0 -0.29 -0.9475 -0.8722 3188918 PK04_107103 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F04 compound treatment 84800.0 -16200.0 -1.49 85200.0 -14400.0 -1.33 -1.9938 -0.9985 3188919 PK04_107104 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F05 compound treatment 85600.0 -15400.0 -1.41 87200.0 -12400.0 -1.15 -1.8107 -0.9946 3188920 PK04_107105 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F06 compound treatment 89600.0 -11400.0 -1.05 92400.0 -7170.0 -0.67 -1.2097 -0.9761 3188921 PK04_107106 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F07 compound treatment 89200.0 -11800.0 -1.08 87200.0 -12400.0 -1.15 -1.5765 -0.9996 3070852 PK04_107107 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F08 compound treatment 86400.0 -14600.0 -1.34 90400.0 -9170.0 -0.85 -1.5489 -0.9759 3188922 PK04_107108 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F09 mock treatment 88000.0 -13000.0 -1.19 90400.0 -9170.0 -0.85 -1.4448 -0.9862 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F10 mock treatment 98400.0 -2570.0 -0.24 86800.0 -12800.0 -1.18 -1.0044 -0.8318 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F11 compound treatment 85600.0 -15400.0 -1.41 84000.0 -15600.0 -1.44 -2.0204 -0.9999 3189029 PK04_107109 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F12 compound treatment 88000.0 -13000.0 -1.19 92400.0 -7170.0 -0.67 -1.3138 -0.9619 3070859 PK04_107110 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F13 compound treatment 78000.0 -23000.0 -2.11 81200.0 -18400.0 -1.7 -2.6983 -0.9943 3189030 PK04_107111 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F14 compound treatment 81200.0 -19800.0 -1.82 83200.0 -16400.0 -1.52 -2.359 -0.996 3189031 PK04_107112 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F15 compound treatment 78000.0 -23000.0 -2.11 80000.0 -19600.0 -1.81 -2.7769 -0.9971 3070862 PK04_107113 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F16 compound treatment 75200.0 -25800.0 -2.37 77200.0 -22400.0 -2.07 -3.1425 -0.9978 3189032 PK04_107114 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F17 mock treatment 94800.0 -6170.0 -0.57 87600.0 -12000.0 -1.11 -1.1861 -0.9515 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F18 mock treatment 97200.0 -3770.0 -0.35 91600.0 -7970.0 -0.74 -0.7678 -0.9404 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F19 compound treatment 82000.0 -19000.0 -1.74 96400.0 -3170.0 -0.29 -1.4418 -0.8149 3189033 PK04_107115 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F20 compound treatment 86800.0 -14200.0 -1.3 88000.0 -11600.0 -1.07 -1.6802 -0.9953 3070022 PK04_107116 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F21 compound treatment 95600.0 -5370.0 -0.49 87200.0 -12400.0 -1.15 -1.1603 -0.9291 3189034 PK04_107117 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F22 compound treatment 93200.0 -7770.0 -0.71 100400.0 825.0 0.08 -0.4512 -0.6278 3189035 PK04_107118 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F23 compound treatment 88800.0 -12200.0 -1.12 95200.0 -4370.0 -0.41 -1.0782 -0.9057 3070031 PK04_107119 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 F24 compound treatment 98000.0 -2970.0 -0.27 102000.0 2430.0 0.22 -0.0341 -0.0965 3189036 PK04_107120 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G01 compound treatment 105600.0 4630.0 0.43 101600.0 2030.0 0.19 0.434 0.9322 3220772 PK04_107121 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G02 compound treatment 100400.0 -569.0 -0.05 96800.0 -2770.0 -0.26 -0.2188 -0.8339 3070078 PK04_107122 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G03 mock treatment 99200.0 -1770.0 -0.16 104000.0 4430.0 0.41 0.175 0.3966 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G04 mock treatment 102800.0 1830.0 0.17 99600.0 25.4 0.0 0.1208 0.7169 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G05 compound treatment 99200.0 -1770.0 -0.16 95600.0 -3970.0 -0.37 -0.3755 -0.9325 3220775 PK04_107123 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G06 compound treatment 81600.0 -19400.0 -1.78 80800.0 -18800.0 -1.74 -2.4903 -0.9999 3070081 PK04_107124 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G07 compound treatment 87600.0 -13400.0 -1.23 89200.0 -10400.0 -0.96 -1.5495 -0.9926 3189039 PK04_107125 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G08 compound treatment 91200.0 -9770.0 -0.9 81200.0 -18400.0 -1.7 -1.8397 -0.9554 3189040 PK04_107126 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G09 compound treatment 89200.0 -11800.0 -1.08 97600.0 -1970.0 -0.18 -0.8949 -0.8151 3070086 PK04_107127 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G10 compound treatment 87200.0 -13800.0 -1.27 81600.0 -18000.0 -1.67 -2.0736 -0.9908 3189041 PK04_107128 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G11 compound treatment 96800.0 -4170.0 -0.38 87200.0 -12400.0 -1.15 -1.0822 -0.8948 3070089 PK04_107129 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G12 compound treatment 84000.0 -17000.0 -1.56 85200.0 -14400.0 -1.33 -2.0458 -0.9969 3189042 PK04_107130 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G13 compound treatment 91600.0 -9370.0 -0.86 90400.0 -9170.0 -0.85 -1.2107 -1.0 3070134 PK04_107131 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G14 compound treatment 94400.0 -6570.0 -0.6 96400.0 -3170.0 -0.29 -0.6353 -0.9453 3070137 PK04_107132 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G15 compound treatment 91200.0 -9770.0 -0.9 90000.0 -9570.0 -0.89 -1.2629 -1.0 3189043 PK04_107133 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G16 compound treatment 88400.0 -12600.0 -1.16 97200.0 -2370.0 -0.22 -0.9731 -0.8269 3189044 PK04_107134 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G17 compound treatment 82800.0 -18200.0 -1.67 80400.0 -19200.0 -1.78 -2.4385 -0.9995 3070143 PK04_107135 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G18 compound treatment 86000.0 -15000.0 -1.38 88000.0 -11600.0 -1.07 -1.7322 -0.9924 3189045 PK04_107136 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G19 mock treatment 103600.0 2630.0 0.24 96800.0 -2770.0 -0.26 -0.0107 -0.0303 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G20 mock treatment 99600.0 -1370.0 -0.13 102800.0 3230.0 0.3 0.1224 0.3772 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G21 compound treatment 102000.0 1030.0 0.09 97600.0 -1970.0 -0.18 -0.0623 -0.3024 3070191 PK04_107137 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G22 compound treatment 64400.0 -36600.0 -3.36 63200.0 -36400.0 -3.37 -4.7626 -1.0 3189046 PK04_107138 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G23 compound treatment 110000.0 9030.0 0.83 108400.0 8830.0 0.82 1.1658 1.0 3070196 PK04_107139 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 G24 compound treatment 103600.0 2630.0 0.24 106000.0 6430.0 0.6 0.5923 0.9213 3189047 PK04_107140 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H01 compound treatment 93600.0 -7370.0 -0.68 96800.0 -2770.0 -0.26 -0.6611 -0.912 3189157 PK04_107141 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H02 compound treatment 97600.0 -3370.0 -0.31 100400.0 825.0 0.08 -0.165 -0.517 3189158 PK04_107142 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H03 mock treatment 100800.0 -169.0 -0.02 104800.0 5230.0 0.48 0.3315 0.6841 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H04 mock treatment 104000.0 3030.0 0.28 94800.0 -4770.0 -0.44 -0.1158 -0.2213 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H05 compound treatment 88800.0 -12200.0 -1.12 90400.0 -9170.0 -0.85 -1.3928 -0.9908 3070201 PK04_107143 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H06 compound treatment 90000.0 -11000.0 -1.01 102800.0 3230.0 0.3 -0.502 -0.4771 3189159 PK04_107144 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H07 compound treatment 84800.0 -16200.0 -1.49 84000.0 -15600.0 -1.44 -2.0724 -0.9999 3071172 PK04_107145 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H08 compound treatment 86800.0 -14200.0 -1.3 89600.0 -9970.0 -0.92 -1.5753 -0.9859 3071173 PK04_107146 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H09 compound treatment 82400.0 -18600.0 -1.71 79600.0 -20000.0 -1.85 -2.5169 -0.9992 3071174 PK04_107147 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H10 compound treatment 84400.0 -16600.0 -1.52 78000.0 -21600.0 -2.0 -2.4917 -0.991 3189160 PK04_107148 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H11 compound treatment 80000.0 -21000.0 -1.93 78000.0 -21600.0 -2.0 -2.7779 -0.9998 3189161 PK04_107149 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H12 compound treatment 94800.0 -6170.0 -0.57 86400.0 -13200.0 -1.22 -1.2647 -0.9392 3071175 PK04_107150 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H13 compound treatment 75600.0 -25400.0 -2.33 73200.0 -26400.0 -2.44 -3.3787 -0.9997 3189162 PK04_107151 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H14 compound treatment 80800.0 -20200.0 -1.86 83600.0 -16000.0 -1.48 -2.3588 -0.9938 3189163 PK04_107152 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H15 compound treatment 74400.0 -26600.0 -2.44 73200.0 -26400.0 -2.44 -3.4567 -1.0 3071176 PK04_107153 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H16 compound treatment 95200.0 -5770.0 -0.53 96400.0 -3170.0 -0.29 -0.5833 -0.9613 3189164 PK04_107154 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H17 compound treatment 84400.0 -16600.0 -1.52 84000.0 -15600.0 -1.44 -2.0985 -0.9996 3189165 PK04_107155 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H18 compound treatment 102400.0 1430.0 0.13 86400.0 -13200.0 -1.22 -0.7704 -0.6272 3071177 PK04_107156 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H19 mock treatment 98800.0 -2170.0 -0.2 97600.0 -1970.0 -0.18 -0.2705 -0.9991 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H20 mock treatment 91200.0 -9770.0 -0.9 101600.0 2030.0 0.19 -0.5026 -0.5476 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H21 compound treatment 87200.0 -13800.0 -1.27 81600.0 -18000.0 -1.67 -2.0736 -0.9908 3189166 PK04_107157 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H22 compound treatment 102400.0 1430.0 0.13 98400.0 -1170.0 -0.11 0.0161 0.0943 3189167 PK04_107158 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H23 compound treatment 92000.0 -8970.0 -0.82 92800.0 -6770.0 -0.63 -1.0274 -0.9909 3071178 PK04_107159 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 H24 compound treatment 98400.0 -2570.0 -0.24 98800.0 -775.0 -0.07 -0.2178 -0.8821 3189168 PK04_107160 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I01 compound treatment 108800.0 7830.0 0.72 108000.0 8430.0 0.78 1.0616 0.9992 3071179 PK04_107161 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I02 compound treatment 105600.0 4630.0 0.43 100800.0 1230.0 0.11 0.3815 0.8654 3189169 PK04_107162 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I03 compound treatment 101200.0 231.0 0.02 91200.0 -8370.0 -0.78 -0.5338 -0.6875 3071180 PK04_107163 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I04 compound treatment 75200.0 -25800.0 -2.37 72800.0 -26800.0 -2.48 -3.4309 -0.9997 3189170 PK04_107164 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I05 mock treatment 102800.0 1830.0 0.17 100000.0 425.0 0.04 0.147 0.8497 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I06 mock treatment 101200.0 231.0 0.02 98000.0 -1570.0 -0.15 -0.0882 -0.5977 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I07 compound treatment 75200.0 -25800.0 -2.37 63200.0 -36400.0 -3.37 -4.0601 -0.9851 3071181 PK04_107165 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I08 compound treatment 99600.0 -1370.0 -0.13 90000.0 -9570.0 -0.89 -0.7166 -0.7994 3189171 PK04_107166 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I09 compound treatment 43600.0 -57400.0 -5.28 41200.0 -58400.0 -5.41 -7.5574 -0.9999 3189172 PK04_107167 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I10 compound treatment 92800.0 -8170.0 -0.75 95200.0 -4370.0 -0.41 -0.818 -0.9581 3071182 PK04_107168 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I11 compound treatment 83600.0 -17400.0 -1.6 88800.0 -10800.0 -1.0 -1.8359 -0.9744 3189173 PK04_107169 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I12 compound treatment 82400.0 -18600.0 -1.71 89200.0 -10400.0 -0.96 -1.8877 -0.9631 3189286 PK04_107170 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I13 compound treatment 79200.0 -21800.0 -2.0 78000.0 -21600.0 -2.0 -2.8299 -1.0 3071183 PK04_107171 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I14 compound treatment 53600.0 -47400.0 -4.36 60400.0 -39200.0 -3.63 -5.6486 -0.9959 3189287 PK04_107172 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I15 compound treatment 86000.0 -15000.0 -1.38 86400.0 -13200.0 -1.22 -1.8371 -0.9982 3071184 PK04_107173 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I16 compound treatment 70000.0 -31000.0 -2.85 74400.0 -25200.0 -2.33 -3.6643 -0.9951 3189288 PK04_107174 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I17 compound treatment 92000.0 -8970.0 -0.82 92800.0 -6770.0 -0.63 -1.0274 -0.9909 3071185 PK04_107175 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I18 compound treatment 56400.0 -44600.0 -4.1 70400.0 -29200.0 -2.7 -4.811 -0.9796 3189289 PK04_107176 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I19 compound treatment 95200.0 -5770.0 -0.53 101600.0 2030.0 0.19 -0.2425 -0.4308 3071186 PK04_107177 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I20 compound treatment 88800.0 -12200.0 -1.12 96800.0 -2770.0 -0.26 -0.9733 -0.8475 3189171 PK04_107178 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I21 mock treatment 106400.0 5430.0 0.5 98000.0 -1570.0 -0.15 0.2501 0.4804 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I22 mock treatment 106000.0 5030.0 0.46 107200.0 7630.0 0.71 0.827 0.9789 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I23 compound treatment 102000.0 1030.0 0.09 103600.0 4030.0 0.37 0.3309 0.8595 3189290 PK04_107179 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 I24 compound treatment 96000.0 -4970.0 -0.46 105600.0 6030.0 0.56 0.0717 0.0994 3071182 PK04_107180 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J01 compound treatment 82400.0 -18600.0 -1.71 94800.0 -4770.0 -0.44 -1.5207 -0.8619 3189291 PK04_107181 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J02 compound treatment 85200.0 -15800.0 -1.45 91600.0 -7970.0 -0.74 -1.5483 -0.9511 3071187 PK04_107182 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J03 compound treatment 96800.0 -4170.0 -0.38 92400.0 -7170.0 -0.67 -0.7414 -0.9658 3189292 PK04_107183 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J04 compound treatment 94400.0 -6570.0 -0.6 94800.0 -4770.0 -0.44 -0.7402 -0.9883 3189293 PK04_107184 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J05 mock treatment 100000.0 -969.0 -0.09 98800.0 -775.0 -0.07 -0.1138 -0.9943 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J06 mock treatment 98800.0 -2170.0 -0.2 95600.0 -3970.0 -0.37 -0.4016 -0.9585 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J07 compound treatment 88400.0 -12600.0 -1.16 90000.0 -9570.0 -0.89 -1.445 -0.9915 3071188 PK04_107185 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J08 compound treatment 82400.0 -18600.0 -1.71 78400.0 -21200.0 -1.96 -2.5956 -0.9976 3189294 PK04_107186 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J09 compound treatment 81600.0 -19400.0 -1.78 82000.0 -17600.0 -1.63 -2.4117 -0.999 3189295 PK04_107187 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J10 compound treatment 90400.0 -10600.0 -0.97 90800.0 -8770.0 -0.81 -1.2625 -0.9961 3071189 PK04_107188 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J11 compound treatment 84000.0 -17000.0 -1.56 86000.0 -13600.0 -1.26 -1.9934 -0.9943 3189296 PK04_107189 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J12 compound treatment 82000.0 -19000.0 -1.74 86800.0 -12800.0 -1.18 -2.071 -0.9822 3189297 PK04_107190 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J13 compound treatment 81200.0 -19800.0 -1.82 84800.0 -14800.0 -1.37 -2.2542 -0.9902 3071190 PK04_107191 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J14 compound treatment 98800.0 -2170.0 -0.2 95600.0 -3970.0 -0.37 -0.4016 -0.9585 3189298 PK04_107192 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J15 compound treatment 86400.0 -14600.0 -1.34 86400.0 -13200.0 -1.22 -1.8111 -0.9989 3071191 PK04_107193 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J16 compound treatment 85600.0 -15400.0 -1.41 90000.0 -9570.0 -0.89 -1.6272 -0.9748 3189299 PK04_107194 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J17 compound treatment 85600.0 -15400.0 -1.41 89200.0 -10400.0 -0.96 -1.6796 -0.9824 3189300 PK04_107195 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J18 compound treatment 80400.0 -20600.0 -1.89 74800.0 -24800.0 -2.3 -2.9616 -0.9954 3071192 PK04_107196 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J19 compound treatment 96800.0 -4170.0 -0.38 88800.0 -10800.0 -1.0 -0.9773 -0.9136 3189301 PK04_107197 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J20 compound treatment 95200.0 -5770.0 -0.53 93600.0 -5970.0 -0.55 -0.7668 -0.9998 3189302 PK04_107198 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J21 mock treatment 108000.0 7030.0 0.65 99600.0 25.4 0.0 0.459 0.7097 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J22 mock treatment 102000.0 1030.0 0.09 101600.0 2030.0 0.19 0.1998 0.95 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J23 compound treatment 99200.0 -1770.0 -0.16 101600.0 2030.0 0.19 0.0177 0.0713 3071251 PK04_107199 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 J24 compound treatment 90400.0 -10600.0 -0.97 93200.0 -6370.0 -0.59 -1.1052 -0.9715 3189414 PK04_107200 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K01 compound treatment 104000.0 3030.0 0.28 106400.0 6830.0 0.63 0.6445 0.9322 3071252 PK04_107201 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K02 compound treatment 100000.0 -969.0 -0.09 103200.0 3630.0 0.34 0.1746 0.5022 3189415 PK04_107202 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K03 compound treatment 98800.0 -2170.0 -0.2 98000.0 -1570.0 -0.15 -0.2443 -0.9882 3071253 PK04_107203 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K04 compound treatment 94800.0 -6170.0 -0.57 73600.0 -26000.0 -2.41 -2.1037 -0.8505 3189416 PK04_107204 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K05 compound treatment 103200.0 2230.0 0.21 92000.0 -7570.0 -0.7 -0.3513 -0.4803 3189417 PK04_107205 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K06 compound treatment 77600.0 -23400.0 -2.15 71600.0 -28000.0 -2.59 -3.3535 -0.9957 3071254 PK04_107206 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K07 mock treatment 96800.0 -4170.0 -0.38 92000.0 -7570.0 -0.7 -0.7676 -0.9595 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K08 mock treatment 93600.0 -7370.0 -0.68 98800.0 -775.0 -0.07 -0.5301 -0.7777 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K09 compound treatment 92400.0 -8570.0 -0.79 92400.0 -7170.0 -0.67 -1.0276 -0.9964 3071255 PK04_107207 NC(=N)NCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K10 compound treatment 76800.0 -24200.0 -2.22 67200.0 -32400.0 -3.0 -3.6939 -0.9891 3189418 PK04_107208 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K11 compound treatment 88000.0 -13000.0 -1.19 92800.0 -6770.0 -0.63 -1.2875 -0.9551 3189419 PK04_107209 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K12 compound treatment 62000.0 -39000.0 -3.58 70000.0 -29600.0 -2.74 -4.473 -0.9912 3071256 PK04_107210 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K13 compound treatment 73600.0 -27400.0 -2.52 72000.0 -27600.0 -2.56 -3.5874 -1.0 3189420 PK04_107211 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K14 compound treatment 70000.0 -31000.0 -2.85 75200.0 -24400.0 -2.26 -3.6118 -0.9934 3071257 PK04_107212 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K15 mock treatment 96800.0 -4170.0 -0.38 101200.0 1630.0 0.15 -0.1646 -0.3996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K16 mock treatment 99200.0 -1770.0 -0.16 95600.0 -3970.0 -0.37 -0.3755 -0.9325 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K17 compound treatment 94400.0 -6570.0 -0.6 100800.0 1230.0 0.11 -0.3469 -0.5643 1035256 PK04_107213 C#CCNCc1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K18 compound treatment 96400.0 -4570.0 -0.42 92800.0 -6770.0 -0.63 -0.7412 -0.9809 3189421 PK04_107214 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K19 compound treatment 99200.0 -1770.0 -0.16 101200.0 1630.0 0.15 -0.0085 -0.0384 3071258 PK04_107215 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K20 compound treatment 102800.0 1830.0 0.17 103200.0 3630.0 0.34 0.3567 0.949 3189422 PK04_107216 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K21 compound treatment 111200.0 10200.0 0.94 99200.0 -375.0 -0.03 0.6409 0.6806 3189423 PK04_107217 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K22 compound treatment 79200.0 -21800.0 -2.0 98400.0 -1170.0 -0.11 -1.4929 -0.7445 3071259 PK04_107218 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K23 mock treatment 109200.0 8230.0 0.76 107200.0 7630.0 0.71 1.0352 0.9994 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 K24 mock treatment 114400.0 13400.0 1.24 104400.0 4830.0 0.45 1.1899 0.9056 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L01 compound treatment 102400.0 1430.0 0.13 96400.0 -3170.0 -0.29 -0.115 -0.3567 3189424 PK04_107219 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L02 compound treatment 110000.0 9030.0 0.83 109200.0 9630.0 0.89 1.2183 0.9994 3189425 PK04_107220 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L03 compound treatment 97200.0 -3770.0 -0.35 92400.0 -7170.0 -0.67 -0.7154 -0.9539 3071260 PK04_107221 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L04 compound treatment 94000.0 -6970.0 -0.64 101600.0 2030.0 0.19 -0.3205 -0.4799 3189426 PK04_107222 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L05 compound treatment 92000.0 -8970.0 -0.82 92800.0 -6770.0 -0.63 -1.0274 -0.9909 3189427 PK04_107223 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L06 compound treatment 99200.0 -1770.0 -0.16 92000.0 -7570.0 -0.7 -0.6115 -0.8485 3071261 PK04_107224 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L07 mock treatment 98800.0 -2170.0 -0.2 97200.0 -2370.0 -0.22 -0.2967 -0.9988 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L08 mock treatment 98000.0 -2970.0 -0.27 106400.0 6830.0 0.63 0.2543 0.369 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L09 compound treatment 95600.0 -5370.0 -0.49 99600.0 25.4 0.0 -0.3475 -0.7037 3189428 PK04_107225 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L10 compound treatment 89600.0 -11400.0 -1.05 84800.0 -14800.0 -1.37 -1.7078 -0.9911 3189429 PK04_107226 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L11 compound treatment 83600.0 -17400.0 -1.6 84400.0 -15200.0 -1.41 -2.1243 -0.998 3071262 PK04_107227 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L12 compound treatment 78000.0 -23000.0 -2.11 78000.0 -21600.0 -2.0 -2.908 -0.9996 3189430 PK04_107228 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L13 compound treatment 84800.0 -16200.0 -1.49 84800.0 -14800.0 -1.37 -2.02 -0.9992 3189431 PK04_107229 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L14 compound treatment 94400.0 -6570.0 -0.6 92800.0 -6770.0 -0.63 -0.8713 -0.9998 3071263 PK04_107230 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L15 mock treatment 97600.0 -3370.0 -0.31 99200.0 -375.0 -0.03 -0.2437 -0.7814 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L16 mock treatment 101600.0 631.0 0.06 98000.0 -1570.0 -0.15 -0.0621 -0.3956 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L17 compound treatment 88800.0 -12200.0 -1.12 93200.0 -6370.0 -0.59 -1.2093 -0.9554 3189432 PK04_107231 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L18 compound treatment 97600.0 -3370.0 -0.31 101200.0 1630.0 0.15 -0.1126 -0.3267 3189547 PK04_107232 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L19 compound treatment 94400.0 -6570.0 -0.6 93200.0 -6370.0 -0.59 -0.8451 -0.9999 3071264 PK04_107233 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L20 compound treatment 90000.0 -11000.0 -1.01 87600.0 -12000.0 -1.11 -1.4983 -0.9989 3189548 PK04_107234 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L21 compound treatment 100400.0 -569.0 -0.05 97200.0 -2370.0 -0.22 -0.1926 -0.8515 3189549 PK04_107235 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L22 compound treatment 100000.0 -969.0 -0.09 104400.0 4830.0 0.45 0.2533 0.5553 3071265 PK04_107236 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L23 mock treatment 108000.0 7030.0 0.65 102000.0 2430.0 0.22 0.6163 0.9001 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 L24 mock treatment 105200.0 4230.0 0.39 100400.0 825.0 0.08 0.3293 0.8302 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M01 compound treatment 98400.0 -2570.0 -0.24 106800.0 7230.0 0.67 0.3065 0.4316 3189550 PK04_107237 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M02 compound treatment 84400.0 -16600.0 -1.52 81200.0 -18400.0 -1.7 -2.282 -0.9985 3071266 PK04_107238 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M03 compound treatment 101200.0 231.0 0.02 100000.0 425.0 0.04 0.0429 0.9581 3189551 PK04_107239 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M04 compound treatment 98400.0 -2570.0 -0.24 103200.0 3630.0 0.34 0.0705 0.1717 3189552 PK04_107240 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M05 compound treatment 98000.0 -2970.0 -0.27 104800.0 5230.0 0.48 0.1494 0.2687 3071267 PK04_107241 CN(C)S(=O)(=O)NCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M06 compound treatment 102800.0 1830.0 0.17 100400.0 825.0 0.08 0.1732 0.9362 3189553 PK04_107242 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M07 compound treatment 95600.0 -5370.0 -0.49 92800.0 -6770.0 -0.63 -0.7932 -0.9929 3414058 PK04_107243 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M08 compound treatment 102000.0 1030.0 0.09 96400.0 -3170.0 -0.29 -0.141 -0.456 3189554 PK04_107244 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M09 mock treatment 100000.0 -969.0 -0.09 99600.0 25.4 0.0 -0.0613 -0.6882 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M10 mock treatment 98000.0 -2970.0 -0.27 94000.0 -5570.0 -0.52 -0.5585 -0.9556 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M11 compound treatment 98400.0 -2570.0 -0.24 109200.0 9630.0 0.89 0.4638 0.5025 3189555 PK04_107245 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M12 compound treatment 99200.0 -1770.0 -0.16 102800.0 3230.0 0.3 0.0964 0.2831 3071269 PK04_107246 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M13 mock treatment 94800.0 -6170.0 -0.57 99600.0 25.4 0.0 -0.3996 -0.7042 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M14 mock treatment 98000.0 -2970.0 -0.27 98000.0 -1570.0 -0.15 -0.2963 -0.9569 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M15 compound treatment 112000.0 11000.0 1.01 108800.0 9230.0 0.86 1.3222 0.9964 3189556 PK04_107247 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M16 compound treatment 79200.0 -21800.0 -2.0 87600.0 -12000.0 -1.11 -2.2007 -0.9613 3189557 PK04_107248 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M17 compound treatment 101600.0 631.0 0.06 101200.0 1630.0 0.15 0.1476 0.9141 3189558 PK04_107249 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M18 compound treatment 83600.0 -17400.0 -1.6 87600.0 -12000.0 -1.11 -1.9145 -0.9842 3071329 PK04_107250 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M19 compound treatment 107200.0 6230.0 0.57 106400.0 6830.0 0.63 0.8526 0.9988 3189559 PK04_107251 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M20 compound treatment 90800.0 -10200.0 -0.94 100000.0 425.0 0.04 -0.6335 -0.6767 3071330 PK04_107252 CCCC#C[Si](O[C@H](CC)c1cn(Cc2cccc(Cl)c2)nn1)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M21 compound treatment 92400.0 -8570.0 -0.79 103600.0 4030.0 0.37 -0.2935 -0.3366 3189560 PK04_107253 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M22 compound treatment 92400.0 -8570.0 -0.79 97600.0 -1970.0 -0.18 -0.6868 -0.8487 3071331 PK04_107254 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M23 compound treatment 111600.0 10600.0 0.98 105600.0 6030.0 0.56 1.0864 0.9647 3189561 PK04_107255 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 M24 compound treatment 95200.0 -5770.0 -0.53 86800.0 -12800.0 -1.18 -1.2125 -0.9344 3071332 PK04_107256 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N01 compound treatment 87600.0 -13400.0 -1.23 96400.0 -3170.0 -0.29 -1.0776 -0.8522 3189562 PK04_107257 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N02 compound treatment 103200.0 2230.0 0.21 98800.0 -775.0 -0.07 0.0944 0.434 3189563 PK04_107258 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N03 compound treatment 100000.0 -969.0 -0.09 100800.0 1230.0 0.11 0.0173 0.1199 3071333 PK04_107259 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N04 compound treatment 106400.0 5430.0 0.5 110000.0 10400.0 0.97 1.0366 0.9529 3189564 PK04_107260 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N05 compound treatment 93200.0 -7770.0 -0.71 89600.0 -9970.0 -0.92 -1.1591 -0.9919 3189681 PK04_107261 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N06 compound treatment 93200.0 -7770.0 -0.71 91600.0 -7970.0 -0.74 -1.028 -0.9999 3071334 PK04_107262 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N07 compound treatment 98800.0 -2170.0 -0.2 97600.0 -1970.0 -0.18 -0.2705 -0.9991 3189682 PK04_107263 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N08 compound treatment 94000.0 -6970.0 -0.64 88800.0 -10800.0 -1.0 -1.1595 -0.977 3071335 PK04_107264 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N09 mock treatment 103600.0 2630.0 0.24 106800.0 7230.0 0.67 0.6447 0.9053 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N10 mock treatment 112400.0 11400.0 1.05 103200.0 3630.0 0.34 0.9811 0.8888 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N11 compound treatment 98400.0 -2570.0 -0.24 96000.0 -3570.0 -0.33 -0.4014 -0.9863 3189683 PK04_107265 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N12 compound treatment 83200.0 -17800.0 -1.63 90400.0 -9170.0 -0.85 -1.757 -0.9537 3189684 PK04_107266 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N13 mock treatment 111600.0 10600.0 0.98 96800.0 -2770.0 -0.26 0.5096 0.504 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N14 mock treatment 101200.0 231.0 0.02 98800.0 -775.0 -0.07 -0.0357 -0.4771 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N15 compound treatment 90000.0 -11000.0 -1.01 94400.0 -5170.0 -0.48 -1.0526 -0.9422 3071336 PK04_107267 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N16 compound treatment 108800.0 7830.0 0.72 109200.0 9630.0 0.89 1.1402 0.9944 3189685 PK04_107268 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N17 compound treatment 98400.0 -2570.0 -0.24 93600.0 -5970.0 -0.55 -0.5587 -0.9279 3189686 PK04_107269 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N18 compound treatment 85200.0 -15800.0 -1.45 89200.0 -10400.0 -0.96 -1.7056 -0.9801 3071337 PK04_107270 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N19 compound treatment 98800.0 -2170.0 -0.2 102400.0 2830.0 0.26 0.0441 0.134 3189687 PK04_107271 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N20 compound treatment 94000.0 -6970.0 -0.64 99200.0 -375.0 -0.03 -0.4778 -0.7443 3189688 PK04_107272 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N21 compound treatment 94400.0 -6570.0 -0.6 100000.0 425.0 0.04 -0.3994 -0.6596 3071339 PK04_107273 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N22 compound treatment 96800.0 -4170.0 -0.38 102400.0 2830.0 0.26 -0.086 -0.1851 3189689 PK04_107274 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N23 compound treatment 112800.0 11800.0 1.09 110000.0 10400.0 0.97 1.4528 0.9982 3189690 PK04_107275 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 N24 compound treatment 98000.0 -2970.0 -0.27 95600.0 -3970.0 -0.37 -0.4536 -0.9891 3071341 PK04_107276 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O01 compound treatment 106800.0 5830.0 0.54 101200.0 1630.0 0.15 0.4858 0.872 3414059 PK04_107277 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O02 compound treatment 100400.0 -569.0 -0.05 93200.0 -6370.0 -0.59 -0.4548 -0.7667 3189692 PK04_107278 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O03 compound treatment 108800.0 7830.0 0.72 106800.0 7230.0 0.67 0.9829 0.9993 3414060 PK04_107279 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O04 compound treatment 94800.0 -6170.0 -0.57 98400.0 -1170.0 -0.11 -0.4782 -0.8277 3189693 PK04_107280 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O05 compound treatment 104000.0 3030.0 0.28 103200.0 3630.0 0.34 0.4348 0.9957 3071393 PK04_107281 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O06 compound treatment 91600.0 -9370.0 -0.86 80000.0 -19600.0 -1.81 -1.8923 -0.9421 3189694 PK04_107282 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O07 compound treatment 102000.0 1030.0 0.09 107600.0 8030.0 0.74 0.5931 0.7909 3189695 PK04_107283 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O08 compound treatment 94800.0 -6170.0 -0.57 100000.0 425.0 0.04 -0.3733 -0.6564 3071395 PK04_107284 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O09 compound treatment 106800.0 5830.0 0.54 102400.0 2830.0 0.26 0.5645 0.9457 3189696 PK04_107285 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O10 compound treatment 100400.0 -569.0 -0.05 92000.0 -7570.0 -0.7 -0.5334 -0.7577 3189697 PK04_107286 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O11 mock treatment 104400.0 3430.0 0.32 115600.0 16000.0 1.49 1.2735 0.8386 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O12 mock treatment 109600.0 8630.0 0.79 100000.0 425.0 0.04 0.5893 0.7413 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O13 compound treatment 105200.0 4230.0 0.39 101200.0 1630.0 0.15 0.3817 0.9147 3071396 PK04_107287 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O14 compound treatment 64000.0 -37000.0 -3.4 68000.0 -31600.0 -2.93 -4.474 -0.9972 3187592 PK04_107288 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O15 compound treatment 80000.0 -21000.0 -1.93 88400.0 -11200.0 -1.04 -2.0963 -0.9575 3187593 PK04_107289 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O16 compound treatment 60800.0 -40200.0 -3.69 72000.0 -27600.0 -2.56 -4.42 -0.9838 3071397 PK04_107290 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O17 compound treatment 87200.0 -13800.0 -1.27 90400.0 -9170.0 -0.85 -1.4969 -0.9812 3187594 PK04_107291 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O18 compound treatment 108000.0 7030.0 0.65 108400.0 8830.0 0.82 1.0358 0.9932 3071398 PK04_107292 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O19 compound treatment 108800.0 7830.0 0.72 114000.0 14400.0 1.34 1.4548 0.9579 3187595 PK04_107293 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O20 compound treatment 122800.0 21800.0 2.01 120400.0 20800.0 1.93 2.7849 0.9998 3071399 PK04_107294 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O21 compound treatment 112000.0 11000.0 1.01 111600.0 12000.0 1.11 1.5057 0.9989 3187594 PK04_107295 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O22 compound treatment 116000.0 15000.0 1.38 110000.0 10400.0 0.97 1.661 0.9847 3187596 PK04_107296 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O23 compound treatment 106400.0 5430.0 0.5 108400.0 8830.0 0.82 0.9317 0.972 3187597 PK04_107297 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 O24 compound treatment 115200.0 14200.0 1.31 108400.0 8830.0 0.82 1.5041 0.9744 3071400 PK04_107298 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P01 compound treatment 95600.0 -5370.0 -0.49 96800.0 -2770.0 -0.26 -0.5311 -0.9538 3187598 PK04_107299 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P02 compound treatment 98400.0 -2570.0 -0.24 92000.0 -7570.0 -0.7 -0.6635 -0.8957 3071401 PK04_107300 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P03 compound treatment 106800.0 5830.0 0.54 102400.0 2830.0 0.26 0.5645 0.9457 3187599 PK04_107301 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P04 compound treatment 104400.0 3430.0 0.32 92800.0 -6770.0 -0.63 -0.2208 -0.3142 3187600 PK04_107302 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P05 compound treatment 100000.0 -969.0 -0.09 96000.0 -3570.0 -0.33 -0.2973 -0.8665 3071402 PK04_107303 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P06 compound treatment 113600.0 12600.0 1.16 112800.0 13200.0 1.23 1.6884 0.9996 3187601 PK04_107304 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P07 compound treatment 95600.0 -5370.0 -0.49 94000.0 -5570.0 -0.52 -0.7146 -0.9997 3187602 PK04_107305 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P08 compound treatment 96000.0 -4970.0 -0.46 99200.0 -375.0 -0.03 -0.3477 -0.7586 3071403 PK04_107306 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P09 compound treatment 99600.0 -1370.0 -0.13 95600.0 -3970.0 -0.37 -0.3495 -0.8978 3187603 PK04_107307 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P10 compound treatment 99600.0 -1370.0 -0.13 89600.0 -9970.0 -0.92 -0.7428 -0.7961 3187604 PK04_107308 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P11 mock treatment 104800.0 3830.0 0.35 109200.0 9630.0 0.89 0.8801 0.9174 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P12 mock treatment 100400.0 -569.0 -0.05 106800.0 7230.0 0.67 0.4366 0.6499 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P13 compound treatment 96800.0 -4170.0 -0.38 100000.0 425.0 0.04 -0.2433 -0.6311 3071404 PK04_107309 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P14 compound treatment 90800.0 -10200.0 -0.94 92000.0 -7570.0 -0.7 -1.1579 -0.99 3187605 PK04_107310 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P15 compound treatment 101200.0 231.0 0.02 102000.0 2430.0 0.22 0.174 0.7706 3187606 PK04_107311 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P16 compound treatment 95600.0 -5370.0 -0.49 92800.0 -6770.0 -0.63 -0.7932 -0.9929 3071405 PK04_107312 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P17 compound treatment 105600.0 4630.0 0.43 97200.0 -2370.0 -0.22 0.1456 0.3036 3187607 PK04_107313 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P18 compound treatment 81600.0 -19400.0 -1.78 82400.0 -17200.0 -1.59 -2.3855 -0.9984 3187608 PK04_107314 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P19 compound treatment 95200.0 -5770.0 -0.53 104800.0 5230.0 0.48 -0.0327 -0.0456 3187728 PK04_107315 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P20 compound treatment 100000.0 -969.0 -0.09 96000.0 -3570.0 -0.33 -0.2973 -0.8665 3071452 PK04_107316 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P21 compound treatment 94000.0 -6970.0 -0.64 101600.0 2030.0 0.19 -0.3205 -0.4799 3187729 PK04_107317 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P22 compound treatment 99200.0 -1770.0 -0.16 94800.0 -4770.0 -0.44 -0.428 -0.9077 3187730 PK04_107318 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P23 compound treatment 108400.0 7430.0 0.68 94800.0 -4770.0 -0.44 0.1704 0.2093 3071453 PK04_107319 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2107 P24 compound treatment 81600.0 -19400.0 -1.78 87600.0 -12000.0 -1.11 -2.0446 -0.9741 3187731 PK04_107320 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A01 compound treatment 94800.0 -11000.0 -1.01 99600.0 -4770.0 -0.44 -1.0252 -0.9318 3187732 PK04_108001 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A02 compound treatment 89600.0 -16200.0 -1.49 82800.0 -21600.0 -2.0 -2.4645 -0.9893 3071454 PK04_108002 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A03 compound treatment 94400.0 -11400.0 -1.04 89200.0 -15200.0 -1.41 -1.7328 -0.9892 3187733 PK04_108003 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A04 compound treatment 98800.0 -6950.0 -0.64 106400.0 2030.0 0.19 -0.3193 -0.4792 3071455 PK04_108004 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A05 compound treatment 93600.0 -12200.0 -1.12 96800.0 -7570.0 -0.7 -1.2867 -0.9749 3187734 PK04_108005 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A06 compound treatment 92400.0 -13400.0 -1.23 75200.0 -29200.0 -2.7 -2.7805 -0.9362 3071456 PK04_108006 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A07 compound treatment 110800.0 5050.0 0.46 105200.0 825.0 0.08 0.3826 0.8126 3187735 PK04_108007 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A08 compound treatment 97600.0 -8150.0 -0.75 96000.0 -8370.0 -0.78 -1.079 -0.9998 3071457 PK04_108008 CC(=CCN[C@H](CO)c1ccccc1)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A09 compound treatment 103200.0 -2550.0 -0.23 100000.0 -4370.0 -0.41 -0.4526 -0.9661 3187736 PK04_108009 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A10 compound treatment 107200.0 1450.0 0.13 107200.0 2830.0 0.26 0.2795 0.951 3071458 PK04_108010 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A11 compound treatment 108000.0 2250.0 0.21 102400.0 -1970.0 -0.18 0.0169 0.0613 3071459 PK04_108011 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A12 compound treatment 34000.0 -71800.0 -6.6 23600.0 -80800.0 -7.49 -9.9609 -0.998 3187737 PK04_108012 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A13 mock treatment 104400.0 -1350.0 -0.12 106400.0 2030.0 0.19 0.0449 0.1997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A14 mock treatment 114000.0 8250.0 0.76 106800.0 2430.0 0.22 0.6956 0.8788 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A15 compound treatment 95200.0 -10600.0 -0.97 95200.0 -9170.0 -0.85 -1.2875 -0.9978 3187738 PK04_108013 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A16 compound treatment 120800.0 15100.0 1.38 111600.0 7230.0 0.67 1.4525 0.9445 3071460 PK04_108014 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A17 compound treatment 96800.0 -8950.0 -0.82 106800.0 2430.0 0.22 -0.4232 -0.4959 3187739 PK04_108015 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A18 compound treatment 92400.0 -13400.0 -1.23 93600.0 -10800.0 -1.0 -1.5745 -0.9947 3071461 PK04_108016 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A19 compound treatment 102000.0 -3750.0 -0.34 101200.0 -3170.0 -0.29 -0.452 -0.9969 3187740 PK04_108017 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A20 compound treatment 106800.0 1050.0 0.1 98000.0 -6370.0 -0.59 -0.3495 -0.5838 3071462 PK04_108018 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A21 compound treatment 104000.0 -1750.0 -0.16 103600.0 -775.0 -0.07 -0.1646 -0.9338 3187741 PK04_108019 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A22 compound treatment 68800.0 -37000.0 -3.4 78400.0 -26000.0 -2.41 -4.1057 -0.9857 3071463 PK04_108020 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A23 compound treatment 109600.0 3850.0 0.35 104000.0 -375.0 -0.03 0.2259 0.6347 3187742 PK04_108021 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 A24 compound treatment 94800.0 -11000.0 -1.01 102000.0 -2370.0 -0.22 -0.8679 -0.8418 3071464 PK04_108022 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B01 compound treatment 114400.0 8650.0 0.8 108800.0 4430.0 0.41 0.8527 0.9525 2133065 PK04_108023 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B02 compound treatment 131200.0 25500.0 2.34 140800.0 36400.0 3.38 4.0427 0.984 3071465 PK04_108024 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B03 compound treatment 106800.0 1050.0 0.1 106000.0 1630.0 0.15 0.1748 0.9769 2133224 PK04_108025 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B04 compound treatment 116800.0 11100.0 1.02 118800.0 14400.0 1.34 1.6642 0.9908 1952196 PK04_108026 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B05 compound treatment 67600.0 -38200.0 -3.51 60000.0 -44400.0 -4.11 -5.3898 -0.9969 2133510 PK04_108027 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B06 compound treatment 89600.0 -16200.0 -1.49 88000.0 -16400.0 -1.52 -2.1237 -0.9999 3071510 PK04_108028 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B07 compound treatment 108400.0 2650.0 0.24 106400.0 2030.0 0.19 0.3051 0.9917 2128988 PK04_108029 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B08 compound treatment 88400.0 -17400.0 -1.6 73600.0 -30800.0 -2.85 -3.1455 -0.9623 3187870 PK04_108030 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B09 compound treatment 104000.0 -1750.0 -0.16 106000.0 1630.0 0.15 -0.0073 -0.0331 3187871 PK04_108031 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B10 compound treatment 89200.0 -16600.0 -1.52 89600.0 -14800.0 -1.37 -2.0448 -0.9986 3071511 PK04_108032 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B11 compound treatment 94800.0 -11000.0 -1.01 86800.0 -17600.0 -1.63 -1.8641 -0.9733 2129008 PK04_108033 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B12 compound treatment 95200.0 -10600.0 -0.97 96400.0 -7970.0 -0.74 -1.2089 -0.991 3187872 PK04_108034 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B13 mock treatment 114800.0 9050.0 0.83 112000.0 7630.0 0.71 1.0884 0.9967 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B14 mock treatment 108400.0 2650.0 0.24 115200.0 10800.0 1.0 0.8819 0.854 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B15 compound treatment 109200.0 3450.0 0.32 97600.0 -6770.0 -0.63 -0.2196 -0.3122 3187873 PK04_108035 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CCC\C=C\CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B16 compound treatment 106400.0 650.0 0.06 115200.0 10800.0 1.0 0.7518 0.7479 3414061 PK04_108036 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B17 compound treatment 106800.0 1050.0 0.1 105600.0 1230.0 0.11 0.1486 0.9967 3187874 PK04_108037 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B18 compound treatment 116400.0 10700.0 0.98 116800.0 12400.0 1.15 1.5071 0.9968 3071513 PK04_108038 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B19 compound treatment 113600.0 7850.0 0.72 106000.0 1630.0 0.15 0.6171 0.8366 3187875 PK04_108039 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B20 compound treatment 97600.0 -8150.0 -0.75 92400.0 -12000.0 -1.11 -1.3149 -0.9817 3071514 PK04_108040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B21 compound treatment 97600.0 -8150.0 -0.75 99200.0 -5170.0 -0.48 -0.8693 -0.9767 3187876 PK04_108041 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B22 compound treatment 71600.0 -34200.0 -3.14 64000.0 -40400.0 -3.74 -4.8674 -0.9962 3071515 PK04_108042 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B23 compound treatment 112400.0 6650.0 0.61 110800.0 6430.0 0.6 0.8537 0.9999 3187877 PK04_108043 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 B24 compound treatment 66400.0 -39400.0 -3.62 67200.0 -37200.0 -3.45 -4.9959 -0.9997 3071516 PK04_108044 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C01 compound treatment 106800.0 1050.0 0.1 98000.0 -6370.0 -0.59 -0.3495 -0.5838 3187878 PK04_108045 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C02 compound treatment 106400.0 650.0 0.06 96400.0 -7970.0 -0.74 -0.4804 -0.6478 3071464 PK04_108046 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C03 compound treatment 100400.0 -5350.0 -0.49 98400.0 -5970.0 -0.55 -0.7396 -0.9983 3187879 PK04_108047 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C04 compound treatment 98400.0 -7350.0 -0.68 90800.0 -13600.0 -1.26 -1.3678 -0.9576 3071517 PK04_108048 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C05 compound treatment 100400.0 -5350.0 -0.49 92400.0 -12000.0 -1.11 -1.1328 -0.933 3071518 PK04_108049 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C06 compound treatment 100400.0 -5350.0 -0.49 94800.0 -9570.0 -0.89 -0.9755 -0.9613 3187880 PK04_108050 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C07 compound treatment 108400.0 2650.0 0.24 99600.0 -4770.0 -0.44 -0.1406 -0.2782 3187881 PK04_108051 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C08 compound treatment 5600.0 -100000.0 -9.21 4400.0 -100000.0 -9.27 -13.0665 -1.0 3071519 PK04_108052 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C09 compound treatment 98800.0 -6950.0 -0.64 94400.0 -9970.0 -0.92 -1.1058 -0.9838 3187882 PK04_108053 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C10 compound treatment 82800.0 -23000.0 -2.11 89600.0 -14800.0 -1.37 -2.4611 -0.978 3071520 PK04_108054 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C11 mock treatment 102400.0 -3350.0 -0.31 102400.0 -1970.0 -0.18 -0.3473 -0.9691 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C12 mock treatment 105200.0 -550.0 -0.05 112400.0 8030.0 0.74 0.4902 0.6575 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C13 compound treatment 98800.0 -6950.0 -0.64 93600.0 -10800.0 -1.0 -1.1582 -0.9768 3187883 PK04_108055 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C14 compound treatment 92400.0 -13400.0 -1.23 91200.0 -13200.0 -1.22 -1.7318 -1.0 3071521 PK04_108056 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C15 mock treatment 108000.0 2250.0 0.21 98000.0 -6370.0 -0.59 -0.2715 -0.4336 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C16 mock treatment 102800.0 -2950.0 -0.27 110000.0 5630.0 0.52 0.1768 0.3008 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C17 compound treatment 106800.0 1050.0 0.1 97600.0 -6770.0 -0.63 -0.3757 -0.5914 3188001 PK04_108057 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C18 compound treatment 105200.0 -550.0 -0.05 105600.0 1230.0 0.11 0.0445 0.3582 3071522 PK04_108058 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C19 compound treatment 104400.0 -1350.0 -0.12 110400.0 6030.0 0.56 0.3071 0.5368 3188002 PK04_108059 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C20 compound treatment 68800.0 -37000.0 -3.4 71600.0 -32800.0 -3.04 -4.5514 -0.9984 3071523 PK04_108060 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C21 compound treatment 113600.0 7850.0 0.72 116800.0 12400.0 1.15 1.325 0.9747 3188003 PK04_108061 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C22 compound treatment 112000.0 6250.0 0.57 108800.0 4430.0 0.41 0.6966 0.9863 3071524 PK04_108062 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C23 compound treatment 115600.0 9850.0 0.91 115200.0 10800.0 1.0 1.3502 0.9987 3188004 PK04_108063 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 C24 compound treatment 115200.0 9450.0 0.87 108400.0 4030.0 0.37 0.8785 0.9287 3071525 PK04_108064 CCOC(=O)C1OC[C@H](N1CC#C)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D01 compound treatment 82000.0 -23800.0 -2.18 79600.0 -24800.0 -2.3 -3.1685 -0.9997 3188005 PK04_108065 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D02 compound treatment 76000.0 -29800.0 -2.74 73600.0 -30800.0 -2.85 -3.952 -0.9998 3414062 PK04_108066 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D03 compound treatment 91600.0 -14200.0 -1.3 86400.0 -18000.0 -1.67 -2.0984 -0.9925 3188006 PK04_108067 CC(C)C[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D04 compound treatment 84000.0 -21800.0 -2.0 84800.0 -19600.0 -1.81 -2.6976 -0.9988 3071527 PK04_108068 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D05 compound treatment 89200.0 -16600.0 -1.52 82400.0 -22000.0 -2.04 -2.5167 -0.9897 3188007 PK04_108069 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D06 compound treatment 59600.0 -46200.0 -4.25 64400.0 -40000.0 -3.71 -5.6217 -0.9977 3071528 PK04_108070 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D07 compound treatment 103200.0 -2550.0 -0.23 106800.0 2430.0 0.22 -0.0069 -0.0212 3188008 PK04_108071 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D08 compound treatment 108000.0 2250.0 0.21 103600.0 -775.0 -0.07 0.0956 0.4363 3071529 PK04_108072 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D09 compound treatment 102000.0 -3750.0 -0.34 96400.0 -7970.0 -0.74 -0.7666 -0.9398 3188009 PK04_108073 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)CNC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D10 compound treatment 107200.0 1450.0 0.13 104800.0 425.0 0.04 0.1222 0.8786 3071530 PK04_108074 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D11 mock treatment 98800.0 -6950.0 -0.64 105600.0 1230.0 0.11 -0.3717 -0.5725 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D12 mock treatment 104800.0 -950.0 -0.09 105600.0 1230.0 0.11 0.0185 0.1293 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D13 compound treatment 99200.0 -6550.0 -0.6 100000.0 -4370.0 -0.41 -0.7127 -0.9814 3188010 PK04_108075 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D14 compound treatment 56800.0 -49000.0 -4.5 62800.0 -41600.0 -3.85 -5.9087 -0.997 3071531 PK04_108076 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D15 mock treatment 105600.0 -150.0 -0.01 101600.0 -2770.0 -0.26 -0.1916 -0.744 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D16 mock treatment 105200.0 -550.0 -0.05 104400.0 25.4 0.0 -0.0341 -0.6735 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D17 compound treatment 96000.0 -9750.0 -0.9 95600.0 -8770.0 -0.81 -1.2093 -0.9988 3071578 PK04_108077 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D18 compound treatment 41600.0 -64200.0 -5.9 28400.0 -76000.0 -7.04 -9.152 -0.9961 3071579 PK04_108078 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D19 compound treatment 92800.0 -13000.0 -1.19 97200.0 -7170.0 -0.67 -1.3125 -0.9621 3071580 PK04_108079 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc6ccccc6)NC2=O)[C@@H]7O[C@]7(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D20 compound treatment 24400.0 -81400.0 -7.48 27200.0 -77200.0 -7.15 -10.3494 -0.9997 3188011 PK04_108080 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D21 compound treatment 98000.0 -7750.0 -0.71 100400.0 -3970.0 -0.37 -0.7646 -0.9528 3188012 PK04_108081 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D22 compound treatment 101600.0 -4150.0 -0.38 103600.0 -775.0 -0.07 -0.3207 -0.8256 3071581 PK04_108082 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D23 compound treatment 102800.0 -2950.0 -0.27 91600.0 -12800.0 -1.18 -1.0291 -0.8472 3188013 PK04_108083 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 D24 compound treatment 106800.0 1050.0 0.1 99200.0 -5170.0 -0.48 -0.2709 -0.5536 3071582 PK04_108084 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E01 mock treatment 108400.0 2650.0 0.24 101600.0 -2770.0 -0.26 -0.0095 -0.0268 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E02 mock treatment 108800.0 3050.0 0.28 102400.0 -1970.0 -0.18 0.069 0.2059 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E03 compound treatment 108800.0 3050.0 0.28 94800.0 -9570.0 -0.89 -0.4292 -0.4611 3188014 PK04_108085 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E04 compound treatment 21600.0 -84200.0 -7.74 16400.0 -88000.0 -8.15 -11.2394 -0.9997 3071583 PK04_108086 C/C=C/CN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E05 compound treatment 95200.0 -10600.0 -0.97 96400.0 -7970.0 -0.74 -1.2089 -0.991 3188015 PK04_108087 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E06 compound treatment 107200.0 1450.0 0.13 99600.0 -4770.0 -0.44 -0.2186 -0.473 3071584 PK04_108088 OCC(NCC#C)/C=C/c1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E07 compound treatment 98000.0 -7750.0 -0.71 97200.0 -7170.0 -0.67 -0.9743 -0.9994 3188129 PK04_108089 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E08 compound treatment 105600.0 -150.0 -0.01 99600.0 -4770.0 -0.44 -0.3227 -0.7288 3071585 PK04_108090 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E09 mock treatment 107600.0 1850.0 0.17 106800.0 2430.0 0.22 0.2793 0.9906 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E10 mock treatment 98800.0 -6950.0 -0.64 102000.0 -2370.0 -0.22 -0.6077 -0.8988 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E11 compound treatment 88000.0 -17800.0 -1.63 83200.0 -21200.0 -1.96 -2.5423 -0.9958 3071586 PK04_108091 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E12 compound treatment 98400.0 -7350.0 -0.68 95200.0 -9170.0 -0.85 -1.0794 -0.9935 3188130 PK04_108092 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E13 compound treatment 98800.0 -6950.0 -0.64 88400.0 -16000.0 -1.48 -1.4991 -0.9295 3188131 PK04_108093 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E14 compound treatment 98400.0 -7350.0 -0.68 95200.0 -9170.0 -0.85 -1.0794 -0.9935 3071587 PK04_108094 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E15 compound treatment 89200.0 -16600.0 -1.52 86800.0 -17600.0 -1.63 -2.2283 -0.9994 3188132 PK04_108095 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E16 compound treatment 88000.0 -17800.0 -1.63 81600.0 -22800.0 -2.11 -2.6472 -0.9919 3071588 PK04_108096 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E17 mock treatment 108800.0 3050.0 0.28 102400.0 -1970.0 -0.18 0.069 0.2059 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E18 mock treatment 108400.0 2650.0 0.24 103600.0 -775.0 -0.07 0.1216 0.4785 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E19 compound treatment 86400.0 -19400.0 -1.78 82400.0 -22000.0 -2.04 -2.6988 -0.9977 3188133 PK04_108097 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E20 compound treatment 92000.0 -13800.0 -1.26 96000.0 -8370.0 -0.78 -1.4432 -0.9725 3071589 PK04_108098 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E21 compound treatment 98800.0 -6950.0 -0.64 100400.0 -3970.0 -0.37 -0.7125 -0.9657 3188134 PK04_108099 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E22 compound treatment 101600.0 -4150.0 -0.38 109200.0 4830.0 0.45 0.0463 0.0788 3071590 PK04_108100 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E23 compound treatment 85200.0 -20600.0 -1.89 94400.0 -9970.0 -0.92 -1.9904 -0.9459 3188135 PK04_108101 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 E24 compound treatment 94800.0 -11000.0 -1.01 104000.0 -375.0 -0.03 -0.7368 -0.731 3071591 PK04_108102 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F01 mock treatment 98800.0 -6950.0 -0.64 100400.0 -3970.0 -0.37 -0.7125 -0.9657 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F02 mock treatment 109200.0 3450.0 0.32 99200.0 -5170.0 -0.48 -0.1148 -0.1995 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F03 compound treatment 97200.0 -8550.0 -0.79 85200.0 -19200.0 -1.78 -1.8129 -0.9328 3188136 PK04_108103 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F04 compound treatment 100800.0 -4950.0 -0.46 94000.0 -10400.0 -0.96 -1.0019 -0.9417 3071592 PK04_108104 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F05 compound treatment 90800.0 -15000.0 -1.38 92000.0 -12400.0 -1.15 -1.7834 -0.9959 3188137 PK04_108105 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F06 compound treatment 99200.0 -6550.0 -0.6 97600.0 -6770.0 -0.63 -0.87 -0.9998 3071592 PK04_108106 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F07 compound treatment 93600.0 -12200.0 -1.12 94000.0 -10400.0 -0.96 -1.4702 -0.9972 3071593 PK04_108107 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F08 compound treatment 77600.0 -28200.0 -2.59 76800.0 -27600.0 -2.56 -3.6382 -1.0 3188138 PK04_108108 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F09 mock treatment 96800.0 -8950.0 -0.82 86800.0 -17600.0 -1.63 -1.734 -0.95 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F10 mock treatment 102000.0 -3750.0 -0.34 90400.0 -14000.0 -1.3 -1.1598 -0.8653 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F11 compound treatment 92800.0 -13000.0 -1.19 83600.0 -20800.0 -1.93 -2.2039 -0.9733 3188139 PK04_108109 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F12 compound treatment 106400.0 650.0 0.06 97600.0 -6770.0 -0.63 -0.4017 -0.6369 3071594 PK04_108110 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F13 compound treatment 91200.0 -14600.0 -1.34 84800.0 -19600.0 -1.81 -2.2293 -0.9888 3188140 PK04_108111 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F14 compound treatment 98000.0 -7750.0 -0.71 86400.0 -18000.0 -1.67 -1.6822 -0.9283 3414064 PK04_108112 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F15 compound treatment 95200.0 -10600.0 -0.97 84800.0 -19600.0 -1.81 -1.9692 -0.957 3071596 PK04_108113 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F16 compound treatment 78000.0 -27800.0 -2.55 75600.0 -28800.0 -2.67 -3.6909 -0.9998 3188141 PK04_108114 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F17 mock treatment 98800.0 -6950.0 -0.64 104000.0 -375.0 -0.03 -0.4766 -0.7444 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F18 mock treatment 97200.0 -8550.0 -0.79 96000.0 -8370.0 -0.78 -1.105 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F19 compound treatment 91200.0 -14600.0 -1.34 82000.0 -22400.0 -2.07 -2.4128 -0.9775 3188142 PK04_108115 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F20 compound treatment 60400.0 -45400.0 -4.17 57600.0 -46800.0 -4.34 -6.0154 -0.9998 3071597 PK04_108116 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F21 compound treatment 98000.0 -7750.0 -0.71 94000.0 -10400.0 -0.96 -1.1841 -0.9891 3188143 PK04_108117 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F22 compound treatment 92800.0 -13000.0 -1.19 90000.0 -14400.0 -1.33 -1.7844 -0.9984 3071598 PK04_108118 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F23 compound treatment 104800.0 -950.0 -0.09 104000.0 -375.0 -0.03 -0.0863 -0.9182 3188144 PK04_108119 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@@H](C)NC4=O)[C@@H]5O[C@@]51C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 F24 compound treatment 30800.0 -75000.0 -6.89 25600.0 -78800.0 -7.3 -10.038 -0.9996 3188260 PK04_108120 CC(=O)O[C@@H]([C@@H]1CCCN1S(=O)(=O)c2ccccc2[N+](=O)[O-])C(=C)C3=CCN(C3)S(=O)(=O)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G01 compound treatment 96400.0 -9350.0 -0.86 90000.0 -14400.0 -1.33 -1.5503 -0.9776 3071599 PK04_108121 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G02 compound treatment 84000.0 -21800.0 -2.0 80400.0 -24000.0 -2.22 -2.986 -0.9986 3188261 PK04_108122 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G03 mock treatment 108000.0 2250.0 0.21 105200.0 825.0 0.08 0.2004 0.9084 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G04 mock treatment 104400.0 -1350.0 -0.12 104000.0 -375.0 -0.03 -0.1124 -0.8714 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G05 compound treatment 90400.0 -15400.0 -1.41 91600.0 -12800.0 -1.18 -1.8357 -0.9962 3188262 PK04_108123 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G06 compound treatment 97200.0 -8550.0 -0.79 87600.0 -16800.0 -1.55 -1.6556 -0.9501 3071600 PK04_108124 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G07 compound treatment 93200.0 -12600.0 -1.15 96800.0 -7570.0 -0.7 -1.3127 -0.9716 3189036 PK04_108125 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G08 compound treatment 100400.0 -5350.0 -0.49 92800.0 -11600.0 -1.07 -1.1066 -0.9375 3071601 PK04_108126 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G09 compound treatment 91200.0 -14600.0 -1.34 86800.0 -17600.0 -1.63 -2.0982 -0.9952 3188263 PK04_108127 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G10 compound treatment 91600.0 -14200.0 -1.3 83200.0 -21200.0 -1.96 -2.3082 -0.9801 3071602 PK04_108128 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G11 compound treatment 86400.0 -19400.0 -1.78 85200.0 -19200.0 -1.78 -2.5153 -1.0 3188264 PK04_108129 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G12 compound treatment 102800.0 -2950.0 -0.27 90000.0 -14400.0 -1.33 -1.134 -0.834 3071603 PK04_108130 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G13 compound treatment 98800.0 -6950.0 -0.64 90000.0 -14400.0 -1.33 -1.3942 -0.9434 3188265 PK04_108131 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G14 compound treatment 84400.0 -21400.0 -1.96 76800.0 -27600.0 -2.56 -3.196 -0.9915 3071604 PK04_108132 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G15 compound treatment 85600.0 -20200.0 -1.85 89200.0 -15200.0 -1.41 -2.3052 -0.9907 3188266 PK04_108133 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G16 compound treatment 81200.0 -24600.0 -2.26 73200.0 -31200.0 -2.89 -3.64 -0.9926 3071651 PK04_108134 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G17 compound treatment 80400.0 -25400.0 -2.33 85600.0 -18800.0 -1.74 -2.8794 -0.9896 3188267 PK04_108135 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G18 compound treatment 87200.0 -18600.0 -1.71 82000.0 -22400.0 -2.07 -2.673 -0.9953 3071652 PK04_108136 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G19 mock treatment 103600.0 -2150.0 -0.2 101600.0 -2770.0 -0.26 -0.3217 -0.9916 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G20 mock treatment 108800.0 3050.0 0.28 106000.0 1630.0 0.15 0.3049 0.9575 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G21 compound treatment 108000.0 2250.0 0.21 93600.0 -10800.0 -1.0 -0.5598 -0.5489 3189164 PK04_108137 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G22 compound treatment 92800.0 -13000.0 -1.19 100000.0 -4370.0 -0.41 -1.129 -0.8972 3071653 PK04_108138 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G23 compound treatment 106000.0 250.0 0.02 101200.0 -3170.0 -0.29 -0.1918 -0.6499 3189167 PK04_108139 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 G24 compound treatment 91600.0 -14200.0 -1.3 102000.0 -2370.0 -0.22 -1.076 -0.8151 3188268 PK04_108140 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H01 compound treatment 99200.0 -6550.0 -0.6 96000.0 -8370.0 -0.78 -0.9749 -0.9922 3188269 PK04_108141 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H02 compound treatment 96800.0 -8950.0 -0.82 89600.0 -14800.0 -1.37 -1.5505 -0.9703 3071654 PK04_108142 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H03 mock treatment 104800.0 -950.0 -0.09 105200.0 825.0 0.08 -0.0077 -0.0662 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H04 mock treatment 107200.0 1450.0 0.13 108800.0 4430.0 0.41 0.3844 0.8911 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H05 compound treatment 99600.0 -6150.0 -0.57 101600.0 -2770.0 -0.26 -0.5819 -0.9364 3188270 PK04_108143 CC(C)C[C@@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H06 compound treatment 102000.0 -3750.0 -0.34 97600.0 -6770.0 -0.63 -0.6879 -0.9602 3071655 PK04_108144 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H07 compound treatment 97200.0 -8550.0 -0.79 95200.0 -9170.0 -0.85 -1.1574 -0.9992 3188271 PK04_108145 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H08 compound treatment 94800.0 -11000.0 -1.01 102400.0 -1970.0 -0.18 -0.8416 -0.8221 3071656 PK04_108146 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H09 compound treatment 75600.0 -30200.0 -2.77 74800.0 -29600.0 -2.74 -3.8994 -1.0 3188272 PK04_108147 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H10 compound treatment 112000.0 6250.0 0.57 102000.0 -2370.0 -0.22 0.2509 0.4075 3071529 PK04_108148 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H11 compound treatment 81600.0 -24200.0 -2.22 74400.0 -30000.0 -2.78 -3.5354 -0.9939 3188273 PK04_108149 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC1=O)[C@@H]6O[C@]6(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H12 compound treatment 106800.0 1050.0 0.1 103600.0 -775.0 -0.07 0.0175 0.1456 3071527 PK04_108150 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H13 compound treatment 94000.0 -11800.0 -1.08 91200.0 -13200.0 -1.22 -1.6277 -0.9981 3071658 PK04_108151 CC(C)C[C@H]1NC(=O)[C@@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H14 compound treatment 94800.0 -11000.0 -1.01 88400.0 -16000.0 -1.48 -1.7592 -0.9824 3188274 PK04_108152 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H15 compound treatment 103200.0 -2550.0 -0.23 86800.0 -17600.0 -1.63 -1.3177 -0.8007 3188275 PK04_108153 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H16 compound treatment 97600.0 -8150.0 -0.75 89200.0 -15200.0 -1.41 -1.5247 -0.9566 3071661 PK04_108154 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H17 compound treatment 89200.0 -16600.0 -1.52 82000.0 -22400.0 -2.07 -2.5429 -0.9884 3188391 PK04_108155 CC(C)C[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H18 compound treatment 83600.0 -22200.0 -2.04 85600.0 -18800.0 -1.74 -2.6712 -0.9969 3071664 PK04_108156 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H19 mock treatment 104000.0 -1750.0 -0.16 103200.0 -1170.0 -0.11 -0.1908 -0.9819 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H20 mock treatment 104800.0 -950.0 -0.09 102400.0 -1970.0 -0.18 -0.1912 -0.9428 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H21 compound treatment 108800.0 3050.0 0.28 100000.0 -4370.0 -0.41 -0.0883 -0.1792 3188392 PK04_108157 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H22 compound treatment 103600.0 -2150.0 -0.2 103200.0 -1170.0 -0.11 -0.2168 -0.9605 3071666 PK04_108158 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H23 compound treatment 114400.0 8650.0 0.8 104400.0 25.4 0.0 0.5643 0.7092 3188393 PK04_108159 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H]6CCCN6C2=O)[C@@H]7O[C@]7(C)[C@H]4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 H24 compound treatment 105600.0 -150.0 -0.01 106400.0 2030.0 0.19 0.123 0.6534 3071711 PK04_108160 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I01 compound treatment 100800.0 -4950.0 -0.46 102000.0 -2370.0 -0.22 -0.4776 -0.9444 3188394 PK04_108161 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I02 compound treatment 86400.0 -19400.0 -1.78 84400.0 -20000.0 -1.85 -2.5677 -0.9998 3071714 PK04_108162 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I03 compound treatment 102000.0 -3750.0 -0.34 104000.0 -375.0 -0.03 -0.2685 -0.7744 3188395 PK04_108163 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I04 compound treatment 88800.0 -17000.0 -1.56 74400.0 -30000.0 -2.78 -3.0671 -0.9627 3071715 PK04_108164 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I05 mock treatment 103600.0 -2150.0 -0.2 102800.0 -1570.0 -0.15 -0.243 -0.9888 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I06 mock treatment 102000.0 -3750.0 -0.34 100000.0 -4370.0 -0.41 -0.5306 -0.9968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I07 compound treatment 96000.0 -9750.0 -0.9 100000.0 -4370.0 -0.41 -0.9209 -0.9356 3188396 PK04_108165 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I08 compound treatment 83200.0 -22600.0 -2.07 78800.0 -25600.0 -2.37 -3.1429 -0.9978 3071717 PK04_108166 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I09 compound treatment 90800.0 -15000.0 -1.38 84800.0 -19600.0 -1.81 -2.2553 -0.9907 3188397 PK04_108167 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I10 compound treatment 94800.0 -11000.0 -1.01 101200.0 -3170.0 -0.29 -0.9203 -0.877 3071720 PK04_108168 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I11 compound treatment 87200.0 -18600.0 -1.71 85600.0 -18800.0 -1.74 -2.4371 -1.0 3188398 PK04_108169 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I12 compound treatment 102400.0 -3350.0 -0.31 85600.0 -18800.0 -1.74 -1.4484 -0.8196 3071724 PK04_108170 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I13 compound treatment 96400.0 -9350.0 -0.86 94800.0 -9570.0 -0.89 -1.2357 -0.9999 3071725 PK04_108171 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I14 compound treatment 94800.0 -11000.0 -1.01 88000.0 -16400.0 -1.52 -1.7854 -0.9802 3071727 PK04_108172 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I15 compound treatment 73600.0 -32200.0 -2.96 69600.0 -34800.0 -3.22 -4.3703 -0.9991 3188399 PK04_108173 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I16 compound treatment 65200.0 -40600.0 -3.73 55600.0 -48800.0 -4.52 -5.8343 -0.9954 3071766 PK04_108174 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I17 compound treatment 66000.0 -39800.0 -3.66 64000.0 -40400.0 -3.74 -5.2317 -0.9999 3188400 PK04_108175 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I18 compound treatment 95600.0 -10200.0 -0.93 98400.0 -5970.0 -0.55 -1.0518 -0.9689 3071767 PK04_108176 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I19 compound treatment 77600.0 -28200.0 -2.59 75200.0 -29200.0 -2.7 -3.7431 -0.9998 3188401 PK04_108177 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I20 compound treatment 101600.0 -4150.0 -0.38 102800.0 -1570.0 -0.15 -0.3731 -0.913 3071770 PK04_108178 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I21 mock treatment 106400.0 650.0 0.06 104400.0 25.4 0.0 0.0439 0.7344 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I22 mock treatment 107600.0 1850.0 0.17 110000.0 5630.0 0.52 0.489 0.8916 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I23 compound treatment 79200.0 -26600.0 -2.44 77200.0 -27200.0 -2.52 -3.508 -0.9999 3188402 PK04_108179 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 I24 compound treatment 35200.0 -70600.0 -6.49 59600.0 -44800.0 -4.15 -7.5234 -0.9767 3071774 PK04_108180 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J01 compound treatment 98800.0 -6950.0 -0.64 99600.0 -4770.0 -0.44 -0.765 -0.9839 3188403 PK04_108181 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J02 compound treatment 94800.0 -11000.0 -1.01 89200.0 -15200.0 -1.41 -1.7068 -0.9866 3071776 PK04_108182 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J03 compound treatment 112400.0 6650.0 0.61 111600.0 7230.0 0.67 0.9061 0.999 3188404 PK04_108183 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J04 compound treatment 110800.0 5050.0 0.46 99600.0 -4770.0 -0.44 0.0155 0.0242 3188405 PK04_108184 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J05 mock treatment 111200.0 5450.0 0.5 99600.0 -4770.0 -0.44 0.0415 0.0621 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J06 mock treatment 108800.0 3050.0 0.28 109600.0 5230.0 0.48 0.5409 0.9663 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J07 compound treatment 98400.0 -7350.0 -0.68 95200.0 -9170.0 -0.85 -1.0794 -0.9935 3070928 PK04_108185 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@H](C)NC4=O)[C@@H]6O[C@@]61C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J08 compound treatment 98000.0 -7750.0 -0.71 102400.0 -1970.0 -0.18 -0.6335 -0.8607 3070929 PK04_108186 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J09 compound treatment 97600.0 -8150.0 -0.75 87200.0 -17200.0 -1.59 -1.6558 -0.941 3070930 PK04_108187 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J10 compound treatment 94800.0 -11000.0 -1.01 92000.0 -12400.0 -1.15 -1.5233 -0.9979 3188406 PK04_108188 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J11 compound treatment 97600.0 -8150.0 -0.75 93200.0 -11200.0 -1.04 -1.2625 -0.9874 3188407 PK04_108189 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J12 compound treatment 100000.0 -5750.0 -0.53 95200.0 -9170.0 -0.85 -0.9753 -0.9739 3070931 PK04_108190 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J13 compound treatment 102400.0 -3350.0 -0.31 96800.0 -7570.0 -0.7 -0.7143 -0.9317 3070932 PK04_108191 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J14 compound treatment 107200.0 1450.0 0.13 99600.0 -4770.0 -0.44 -0.2186 -0.473 3070933 PK04_108192 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J15 compound treatment 88000.0 -17800.0 -1.63 79200.0 -25200.0 -2.33 -2.8045 -0.9847 3188522 PK04_108193 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J16 compound treatment 92800.0 -13000.0 -1.19 98400.0 -5970.0 -0.55 -1.2339 -0.9393 3188523 PK04_108194 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J17 compound treatment 101200.0 -4550.0 -0.42 99600.0 -4770.0 -0.44 -0.6089 -0.9996 3070934 PK04_108195 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J18 compound treatment 104800.0 -950.0 -0.09 109600.0 5230.0 0.48 0.2807 0.5703 3188524 PK04_108196 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J19 compound treatment 100800.0 -4950.0 -0.46 112000.0 7630.0 0.71 0.1778 0.2115 3070935 PK04_108197 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J20 compound treatment 111600.0 5850.0 0.54 107600.0 3230.0 0.3 0.5919 0.9615 3188525 PK04_108198 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J21 mock treatment 104800.0 -950.0 -0.09 116000.0 11600.0 1.08 0.7002 0.6476 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J22 mock treatment 107600.0 1850.0 0.17 111600.0 7230.0 0.67 0.5939 0.8595 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J23 compound treatment 103200.0 -2550.0 -0.23 106400.0 2030.0 0.19 -0.0331 -0.1102 3070936 PK04_108199 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 J24 compound treatment 90000.0 -15800.0 -1.45 83600.0 -20800.0 -1.93 -2.386 -0.9902 3188526 PK04_108200 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K01 compound treatment 115200.0 9450.0 0.87 101600.0 -2770.0 -0.26 0.4328 0.4774 3070937 PK04_108201 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K02 compound treatment 116800.0 11100.0 1.02 113600.0 9230.0 0.86 1.3234 0.9963 3188527 PK04_108202 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K03 compound treatment 116000.0 10300.0 0.94 110000.0 5630.0 0.52 1.0354 0.961 3188528 PK04_108203 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K04 compound treatment 76400.0 -29400.0 -2.7 76000.0 -28400.0 -2.63 -3.7687 -0.9999 3070938 PK04_108204 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K05 compound treatment 94400.0 -11400.0 -1.04 92400.0 -12000.0 -1.11 -1.5231 -0.9995 3188529 PK04_108205 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K06 compound treatment 75600.0 -30200.0 -2.77 70800.0 -33600.0 -3.11 -4.1616 -0.9983 3070939 PK04_108206 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K07 mock treatment 106400.0 650.0 0.06 100800.0 -3570.0 -0.33 -0.192 -0.5703 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K08 mock treatment 98800.0 -6950.0 -0.64 95600.0 -8770.0 -0.81 -1.0272 -0.9929 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K09 compound treatment 57200.0 -48600.0 -4.47 50800.0 -53600.0 -4.97 -6.6692 -0.9986 3188530 PK04_108207 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K10 compound treatment 75200.0 -30600.0 -2.81 69600.0 -34800.0 -3.22 -4.2662 -0.9977 3188531 PK04_108208 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K11 compound treatment 65600.0 -40200.0 -3.69 52400.0 -52000.0 -4.82 -6.018 -0.9914 3070940 PK04_108209 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K12 compound treatment 66800.0 -39000.0 -3.58 62000.0 -42400.0 -3.93 -5.3107 -0.9989 3188532 PK04_108210 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K13 compound treatment 57600.0 -48200.0 -4.43 58800.0 -45600.0 -4.22 -6.1188 -0.9997 3188533 PK04_108211 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K14 compound treatment 83600.0 -22200.0 -2.04 82400.0 -22000.0 -2.04 -2.881 -1.0 3070941 PK04_108212 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K15 mock treatment 104000.0 -1750.0 -0.16 104800.0 425.0 0.04 -0.0859 -0.5186 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K16 mock treatment 103600.0 -2150.0 -0.2 98000.0 -6370.0 -0.59 -0.5576 -0.895 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K17 compound treatment 92800.0 -13000.0 -1.19 94800.0 -9570.0 -0.89 -1.4698 -0.9895 3188534 PK04_108213 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K18 compound treatment 82000.0 -23800.0 -2.18 77600.0 -26800.0 -2.48 -3.2996 -0.998 3070942 PK04_108214 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K19 compound treatment 112000.0 6250.0 0.57 105200.0 825.0 0.08 0.4606 0.7942 3188535 PK04_108215 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K20 compound treatment 93200.0 -12600.0 -1.15 99200.0 -5170.0 -0.48 -1.1554 -0.9243 3070943 PK04_108216 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K21 compound treatment 68400.0 -37400.0 -3.44 78400.0 -26000.0 -2.41 -4.1318 -0.9849 3188536 PK04_108217 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K22 compound treatment 85200.0 -20600.0 -1.89 90800.0 -13600.0 -1.26 -2.2263 -0.9804 3188537 PK04_108218 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K23 mock treatment 110000.0 4250.0 0.39 113200.0 8830.0 0.82 0.8549 0.9429 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 K24 mock treatment 109200.0 3450.0 0.32 114400.0 10000.0 0.93 0.8815 0.8977 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L01 compound treatment 83600.0 -22200.0 -2.04 84000.0 -20400.0 -1.89 -2.7761 -0.9993 3070944 PK04_108219 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L02 compound treatment 110400.0 4650.0 0.43 108800.0 4430.0 0.41 0.5925 0.9998 3188538 PK04_108220 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L03 compound treatment 96800.0 -8950.0 -0.82 93200.0 -11200.0 -1.04 -1.3145 -0.9935 3188539 PK04_108221 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L04 compound treatment 110000.0 4250.0 0.39 108800.0 4430.0 0.41 0.5665 0.9997 3215882 PK04_108222 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L05 compound treatment 105200.0 -550.0 -0.05 104000.0 -375.0 -0.03 -0.0603 -0.9831 3188540 PK04_108223 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L06 compound treatment 97200.0 -8550.0 -0.79 91600.0 -12800.0 -1.18 -1.3934 -0.9802 3215880 PK04_108224 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L07 mock treatment 110800.0 5050.0 0.46 104000.0 -375.0 -0.03 0.3039 0.6524 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L08 mock treatment 101600.0 -4150.0 -0.38 102000.0 -2370.0 -0.22 -0.4256 -0.9658 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L09 compound treatment 106400.0 650.0 0.06 104400.0 25.4 0.0 0.0439 0.7344 3188541 PK04_108225 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L10 compound treatment 94400.0 -11400.0 -1.04 72000.0 -32400.0 -3.0 -2.8601 -0.9002 3188542 PK04_108226 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L11 compound treatment 85200.0 -20600.0 -1.89 71600.0 -32800.0 -3.04 -3.4847 -0.9739 3070947 PK04_108227 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L12 compound treatment 114400.0 8650.0 0.8 92000.0 -12400.0 -1.15 -0.2484 -0.178 3188543 PK04_108228 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L13 compound treatment 85600.0 -20200.0 -1.85 79200.0 -25200.0 -2.33 -2.9606 -0.9935 3188544 PK04_108229 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L14 compound treatment 92800.0 -13000.0 -1.19 81600.0 -22800.0 -2.11 -2.335 -0.9633 3070948 PK04_108230 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L15 mock treatment 100800.0 -4950.0 -0.46 99600.0 -4770.0 -0.44 -0.6349 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L16 mock treatment 96800.0 -8950.0 -0.82 98000.0 -6370.0 -0.59 -0.9999 -0.9868 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L17 compound treatment 99200.0 -6550.0 -0.6 102400.0 -1970.0 -0.18 -0.5554 -0.8821 3188657 PK04_108231 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L18 compound treatment 87600.0 -18200.0 -1.67 92000.0 -12400.0 -1.15 -1.9916 -0.9832 3070949 PK04_108232 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L19 compound treatment 105600.0 -150.0 -0.01 90800.0 -13600.0 -1.26 -0.8995 -0.7148 3188658 PK04_108233 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L20 compound treatment 103200.0 -2550.0 -0.23 106800.0 2430.0 0.22 -0.0069 -0.0212 3070950 PK04_108234 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L21 compound treatment 104800.0 -950.0 -0.09 104800.0 425.0 0.04 -0.0339 -0.3537 3188659 PK04_108235 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L22 compound treatment 112000.0 6250.0 0.57 113200.0 8830.0 0.82 0.985 0.9851 3070951 PK04_108236 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L23 mock treatment 118000.0 12300.0 1.13 114800.0 10400.0 0.97 1.4801 0.9971 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 L24 mock treatment 108800.0 3050.0 0.28 111200.0 6830.0 0.63 0.6457 0.933 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M01 compound treatment 81600.0 -24200.0 -2.22 80000.0 -24400.0 -2.26 -3.1683 -1.0 3188660 PK04_108237 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M02 compound treatment 103200.0 -2550.0 -0.23 92400.0 -12000.0 -1.11 -0.9507 -0.838 3070952 PK04_108238 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M03 compound treatment 80400.0 -25400.0 -2.33 77200.0 -27200.0 -2.52 -3.4299 -0.9993 3188661 PK04_108239 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M04 compound treatment 77600.0 -28200.0 -2.59 74800.0 -29600.0 -2.74 -3.7693 -0.9996 3070953 PK04_108240 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M05 compound treatment 104800.0 -950.0 -0.09 102400.0 -1970.0 -0.18 -0.1912 -0.9428 3188662 PK04_108241 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M06 compound treatment 82400.0 -23400.0 -2.15 80800.0 -23600.0 -2.19 -3.0639 -1.0 3070954 PK04_108242 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M07 compound treatment 106400.0 650.0 0.06 100800.0 -3570.0 -0.33 -0.192 -0.5703 3188663 PK04_108243 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M08 compound treatment 52000.0 -53800.0 -4.94 44800.0 -59600.0 -5.52 -7.4007 -0.9985 3188664 PK04_108244 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M09 mock treatment 104800.0 -950.0 -0.09 96400.0 -7970.0 -0.74 -0.5845 -0.7852 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M10 mock treatment 102000.0 -3750.0 -0.34 94000.0 -10400.0 -0.96 -0.9239 -0.9043 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M11 compound treatment 89200.0 -16600.0 -1.52 86400.0 -18000.0 -1.67 -2.2545 -0.999 3070955 PK04_108245 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M12 compound treatment 74800.0 -31000.0 -2.85 70000.0 -34400.0 -3.19 -4.266 -0.9984 3188665 PK04_108246 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M13 mock treatment 98800.0 -6950.0 -0.64 99200.0 -5170.0 -0.48 -0.7912 -0.99 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M14 mock treatment 111600.0 5850.0 0.54 100400.0 -3970.0 -0.37 0.12 0.184 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M15 compound treatment 88800.0 -17000.0 -1.56 88800.0 -15600.0 -1.44 -2.1233 -0.9993 3188666 PK04_108247 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M16 compound treatment 64000.0 -41800.0 -3.84 70400.0 -34000.0 -3.15 -4.9423 -0.9951 3070994 PK04_108248 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M17 compound treatment 79200.0 -26600.0 -2.44 74400.0 -30000.0 -2.78 -3.6915 -0.9979 3188667 PK04_108249 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M18 compound treatment 97200.0 -8550.0 -0.79 83600.0 -20800.0 -1.93 -1.9177 -0.922 3070995 PK04_108250 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M19 compound treatment 62800.0 -43000.0 -3.95 74800.0 -29600.0 -2.74 -4.732 -0.9841 3188668 PK04_108251 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M20 compound treatment 110000.0 4250.0 0.39 116400.0 12000.0 1.11 1.0646 0.9013 2133134 PK04_108252 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M21 compound treatment 70000.0 -35800.0 -3.29 72400.0 -32000.0 -2.96 -4.421 -0.9987 3070996 PK04_108253 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M22 compound treatment 108000.0 2250.0 0.21 117200.0 12800.0 1.19 0.9869 0.8179 2133147 PK04_108254 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M23 compound treatment 108000.0 2250.0 0.21 97600.0 -6770.0 -0.63 -0.2977 -0.4502 3070997 PK04_108255 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 M24 compound treatment 116000.0 10300.0 0.94 118400.0 14000.0 1.3 1.5859 0.9876 3188671 PK04_108256 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N01 compound treatment 114000.0 8250.0 0.76 106800.0 2430.0 0.22 0.6956 0.8788 3188672 PK04_108257 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N02 compound treatment 96800.0 -8950.0 -0.82 102000.0 -2370.0 -0.22 -0.7378 -0.8657 3070998 PK04_108258 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N03 compound treatment 112000.0 6250.0 0.57 101600.0 -2770.0 -0.26 0.2247 0.3567 3188673 PK04_108259 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N04 compound treatment 104800.0 -950.0 -0.09 106800.0 2430.0 0.22 0.0972 0.4029 3070999 PK04_108260 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N05 compound treatment 90000.0 -15800.0 -1.45 101600.0 -2770.0 -0.26 -1.2063 -0.8198 3188674 PK04_108261 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N06 compound treatment 71600.0 -34200.0 -3.14 72000.0 -32400.0 -3.0 -4.3431 -0.9997 3071000 PK04_108262 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N07 compound treatment 102800.0 -2950.0 -0.27 94000.0 -10400.0 -0.96 -0.8718 -0.8726 3188675 PK04_108263 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N08 compound treatment 100800.0 -4950.0 -0.46 96400.0 -7970.0 -0.74 -0.8446 -0.9729 3188676 PK04_108264 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N09 mock treatment 108000.0 2250.0 0.21 107600.0 3230.0 0.3 0.3577 0.9839 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N10 mock treatment 112400.0 6650.0 0.61 107200.0 2830.0 0.26 0.6177 0.9283 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N11 compound treatment 103200.0 -2550.0 -0.23 99200.0 -5170.0 -0.48 -0.505 -0.9459 3071001 PK04_108265 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N12 compound treatment 102400.0 -3350.0 -0.31 102800.0 -1570.0 -0.15 -0.3211 -0.9417 3188677 PK04_108266 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N13 mock treatment 105200.0 -550.0 -0.05 94400.0 -9970.0 -0.92 -0.6895 -0.7447 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N14 mock treatment 104400.0 -1350.0 -0.12 106800.0 2430.0 0.22 0.0712 0.2771 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N15 compound treatment 111600.0 5850.0 0.54 104000.0 -375.0 -0.03 0.3559 0.6601 3071002 PK04_108267 OCC1CC(=NO1)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N16 compound treatment 87200.0 -18600.0 -1.71 87200.0 -17200.0 -1.59 -2.3322 -0.9994 3188788 PK04_108268 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N17 compound treatment 115600.0 9850.0 0.91 111600.0 7230.0 0.67 1.1142 0.9889 3071004 PK04_108269 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N18 compound treatment 110400.0 4650.0 0.43 110400.0 6030.0 0.56 0.6974 0.9913 3071005 PK04_108270 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N19 compound treatment 110400.0 4650.0 0.43 110400.0 6030.0 0.56 0.6974 0.9913 3414065 PK04_108271 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N20 compound treatment 114800.0 9050.0 0.83 116000.0 11600.0 1.08 1.3506 0.9919 3188790 PK04_108272 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N21 compound treatment 116000.0 10300.0 0.94 102800.0 -1570.0 -0.15 0.5635 0.5906 3071008 PK04_108273 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N22 compound treatment 98000.0 -7750.0 -0.71 110400.0 6030.0 0.56 -0.1092 -0.1205 3188791 PK04_108274 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N23 compound treatment 114800.0 9050.0 0.83 127600.0 23200.0 2.15 2.1109 0.9145 3188792 PK04_108275 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 N24 compound treatment 114400.0 8650.0 0.8 118400.0 14000.0 1.3 1.4819 0.9722 3188793 PK04_108276 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O01 compound treatment 67600.0 -38200.0 -3.51 70000.0 -34400.0 -3.19 -4.7344 -0.9988 3071055 PK04_108277 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O02 compound treatment 117200.0 11500.0 1.05 112000.0 7630.0 0.71 1.2445 0.9812 2129060 PK04_108278 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O03 compound treatment 85600.0 -20200.0 -1.85 72800.0 -31600.0 -2.93 -3.3801 -0.9757 3188794 PK04_108279 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O04 compound treatment 114000.0 8250.0 0.76 118000.0 13600.0 1.26 1.4296 0.9703 2129057 PK04_108280 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O05 compound treatment 83200.0 -22600.0 -2.07 84800.0 -19600.0 -1.81 -2.7497 -0.9978 3188796 PK04_108281 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O06 compound treatment 118000.0 12300.0 1.13 116800.0 12400.0 1.15 1.6112 0.9999 2129061 PK04_108282 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O07 compound treatment 102800.0 -2950.0 -0.27 93200.0 -11200.0 -1.04 -0.9243 -0.8632 3071060 PK04_108283 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O08 compound treatment 106800.0 1050.0 0.1 105600.0 1230.0 0.11 0.1486 0.9967 2129067 PK04_108284 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O09 compound treatment 99200.0 -6550.0 -0.6 96800.0 -7570.0 -0.7 -0.9225 -0.9971 3188797 PK04_108285 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O10 compound treatment 104800.0 -950.0 -0.09 96400.0 -7970.0 -0.74 -0.5845 -0.7852 2129068 PK04_108286 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O11 mock treatment 106400.0 650.0 0.06 104000.0 -375.0 -0.03 0.0177 0.2564 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O12 mock treatment 107600.0 1850.0 0.17 104400.0 25.4 0.0 0.122 0.7168 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O13 compound treatment 103600.0 -2150.0 -0.2 94800.0 -9570.0 -0.89 -0.7674 -0.844 3188798 PK04_108287 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O14 compound treatment 114000.0 8250.0 0.76 108400.0 4030.0 0.37 0.8004 0.9465 3071064 PK04_108288 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O15 compound treatment 65200.0 -40600.0 -3.73 70000.0 -34400.0 -3.19 -4.8905 -0.9969 3188799 PK04_108289 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O16 compound treatment 100400.0 -5350.0 -0.49 108000.0 3630.0 0.34 -0.1104 -0.1852 2133032 PK04_108290 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O17 compound treatment 76800.0 -29000.0 -2.66 64000.0 -40400.0 -3.74 -4.5292 -0.9861 3071066 PK04_108291 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O18 compound treatment 118400.0 12700.0 1.16 112800.0 8430.0 0.78 1.375 0.9812 2133035 PK04_108292 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O19 compound treatment 109600.0 3850.0 0.35 110800.0 6430.0 0.6 0.6715 0.9692 3071068 PK04_108293 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O20 compound treatment 116400.0 10700.0 0.98 114800.0 10400.0 0.97 1.376 1.0 2133267 PK04_108294 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O21 compound treatment 91600.0 -14200.0 -1.3 104400.0 25.4 0.0 -0.9187 -0.7058 3071112 PK04_108295 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O22 compound treatment 117200.0 11500.0 1.05 124000.0 19600.0 1.82 2.031 0.9662 2133153 PK04_108296 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O23 compound treatment 117600.0 11900.0 1.09 116000.0 11600.0 1.08 1.5327 1.0 3188804 PK04_108297 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 O24 compound treatment 119200.0 13500.0 1.24 107600.0 3230.0 0.3 1.0862 0.8534 2132929 PK04_108298 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P01 compound treatment 124400.0 18700.0 1.72 108000.0 3630.0 0.34 1.4507 0.8298 3188805 PK04_108299 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P02 compound treatment 128800.0 23100.0 2.12 119600.0 15200.0 1.41 2.4971 0.9804 3071118 PK04_108300 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P03 compound treatment 116800.0 11100.0 1.02 112800.0 8430.0 0.78 1.2709 0.9915 3188806 PK04_108301 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P04 compound treatment 117200.0 11500.0 1.05 100000.0 -4370.0 -0.41 0.458 0.4058 3071120 PK04_108302 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P05 compound treatment 108400.0 2650.0 0.24 119600.0 15200.0 1.41 1.1703 0.8171 3188807 PK04_108303 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P06 compound treatment 118400.0 12700.0 1.16 116400.0 12000.0 1.11 1.611 0.9998 3188808 PK04_108304 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P07 compound treatment 110800.0 5050.0 0.46 112000.0 7630.0 0.71 0.8282 0.9793 3071124 PK04_108305 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P08 compound treatment 122800.0 17100.0 1.57 115200.0 10800.0 1.0 1.8185 0.9767 3188923 PK04_108306 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P09 compound treatment 116800.0 11100.0 1.02 104800.0 425.0 0.04 0.7466 0.734 3188924 PK04_108307 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P10 compound treatment 83600.0 -22200.0 -2.04 86800.0 -17600.0 -1.63 -2.5926 -0.9939 3071127 PK04_108308 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P11 mock treatment 106400.0 650.0 0.06 116400.0 12000.0 1.11 0.8304 0.744 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P12 mock treatment 116000.0 10300.0 0.94 108800.0 4430.0 0.41 0.9567 0.9305 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P13 compound treatment 111600.0 5850.0 0.54 108000.0 3630.0 0.34 0.6181 0.9743 3188925 PK04_108309 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P14 compound treatment 110800.0 5050.0 0.46 111200.0 6830.0 0.63 0.7758 0.9885 3071425 PK04_108310 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P15 compound treatment 115600.0 9850.0 0.91 115600.0 11200.0 1.04 1.3764 0.9976 3188926 PK04_108311 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P16 compound treatment 124800.0 19100.0 1.75 115600.0 11200.0 1.04 1.9748 0.969 3215868 PK04_108312 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P17 compound treatment 102000.0 -3750.0 -0.34 96000.0 -8370.0 -0.78 -0.7928 -0.9333 3188927 PK04_108313 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P18 compound treatment 90800.0 -15000.0 -1.38 101600.0 -2770.0 -0.26 -1.1542 -0.825 3215866 PK04_108314 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P19 compound treatment 112800.0 7050.0 0.65 110400.0 6030.0 0.56 0.8535 0.9972 3071435 PK04_108315 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P20 compound treatment 116800.0 11100.0 1.02 112800.0 8430.0 0.78 1.2709 0.9915 3071437 PK04_108316 OB1OC(CCc2ccccc2)CC=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P21 compound treatment 107200.0 1450.0 0.13 121600.0 17200.0 1.6 1.2233 0.7635 3188929 PK04_108317 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P22 compound treatment 93600.0 -12200.0 -1.12 97200.0 -7170.0 -0.67 -1.2605 -0.9692 3071483 PK04_108318 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P23 compound treatment 93600.0 -12200.0 -1.12 88800.0 -15600.0 -1.44 -1.8111 -0.992 3188930 PK04_108319 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2108 P24 compound treatment 134400.0 28700.0 2.64 137600.0 33200.0 3.08 4.0411 0.997 3071486 PK04_108320 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A01 compound treatment 113200.0 1950.0 0.18 112400.0 2650.0 0.25 0.3003 0.9881 3131442 CMLD2_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A02 compound treatment 116800.0 5550.0 0.51 122400.0 12600.0 1.17 1.1899 0.9306 3131443 CMLD2_000002 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A03 compound treatment 118400.0 7150.0 0.66 110800.0 1050.0 0.1 0.5337 0.8028 3010137 CMLD2_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A04 compound treatment 116400.0 5150.0 0.47 122400.0 12600.0 1.17 1.1639 0.9205 3131444 CMLD2_000004 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A05 compound treatment 120800.0 9550.0 0.88 116000.0 6250.0 0.58 1.0306 0.9796 3131445 CMLD2_000005 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A06 compound treatment 112800.0 1550.0 0.14 112400.0 2650.0 0.25 0.2743 0.9666 3010139 CMLD2_000006 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A07 compound treatment 116000.0 4750.0 0.44 110000.0 248.0 0.02 0.3252 0.7433 3131446 CMLD2_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A08 compound treatment 111200.0 -50.7 0.0 114400.0 4650.0 0.43 0.3013 0.6994 3010141 CMLD2_000008 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A09 compound treatment 109600.0 -1650.0 -0.15 117600.0 7850.0 0.73 0.407 0.5477 3010141 CMLD2_000009 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A10 compound treatment 111600.0 349.0 0.03 114400.0 4650.0 0.43 0.3274 0.7577 3010142 CMLD2_000010 CC(C)[C@H](O)C1=CCCCC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A11 compound treatment 106000.0 -5250.0 -0.48 91200.0 -18600.0 -1.72 -1.5575 -0.872 3131447 CMLD2_000011 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A12 compound treatment 110400.0 -851.0 -0.08 110800.0 1050.0 0.1 0.0133 0.107 3010143 CMLD2_000012 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A13 mock treatment 122000.0 10700.0 0.99 113600.0 3850.0 0.36 0.9514 0.9051 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A14 mock treatment 113200.0 1950.0 0.18 112400.0 2650.0 0.25 0.3003 0.9881 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A15 compound treatment 113600.0 2350.0 0.22 113200.0 3450.0 0.32 0.3788 0.9818 3131448 CMLD2_000013 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A16 compound treatment 128400.0 17100.0 1.58 122400.0 12600.0 1.17 1.9444 0.9893 3131449 CMLD2_000014 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A17 compound treatment 116400.0 5150.0 0.47 114800.0 5050.0 0.47 0.6658 1.0 3010159 CMLD2_000015 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](C)CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A18 mock treatment 113200.0 1950.0 0.18 112400.0 2650.0 0.25 0.3003 0.9881 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A19 compound treatment 111600.0 349.0 0.03 99600.0 -10200.0 -0.94 -0.6427 -0.6826 3131450 CMLD2_000016 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A20 compound treatment 112400.0 1150.0 0.11 113200.0 3450.0 0.32 0.3007 0.8934 3010162 CMLD2_000017 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A21 compound treatment 107600.0 -3650.0 -0.34 111200.0 1450.0 0.13 -0.1426 -0.3942 3131451 CMLD2_000018 COc1ccc(OC[C@H]2Cc3c(nc4CCN(CCOc5ccccc5)Cc4c3CO2)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A22 compound treatment 98800.0 -12500.0 -1.15 104000.0 -5750.0 -0.53 -1.1868 -0.9395 3131452 CMLD2_000019 COC(=O)C1=C(C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A23 compound treatment 119600.0 8350.0 0.77 113600.0 3850.0 0.36 0.7953 0.9392 3010166 CMLD2_000020 COc1cccc(c1)[C@H]2N[C@@H](CC[C@@H]2C)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 A24 compound treatment 113600.0 2350.0 0.22 102800.0 -6950.0 -0.64 -0.3029 -0.4456 3010168 CMLD2_000021 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)C)c3ccccc3)C(=O)OC)c4ccccc4)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B01 compound treatment 112400.0 1150.0 0.11 110000.0 248.0 0.02 0.091 0.8412 3131453 CMLD2_000022 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B02 compound treatment 122400.0 11100.0 1.03 119200.0 9450.0 0.88 1.3444 0.9969 3131569 CMLD2_000023 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B03 compound treatment 121200.0 9950.0 0.92 127600.0 17800.0 1.65 1.8169 0.961 3131570 CMLD2_000024 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B04 compound treatment 115200.0 3950.0 0.36 130000.0 20200.0 1.88 1.584 0.8286 3010172 CMLD2_000025 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B05 compound treatment 123200.0 11900.0 1.1 121600.0 11800.0 1.1 1.5537 1.0 3131571 CMLD2_000026 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B06 compound treatment 106800.0 -4450.0 -0.41 114400.0 4650.0 0.43 0.0151 0.0255 3010200 CMLD2_000027 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B07 compound treatment 109600.0 -1650.0 -0.15 114400.0 4650.0 0.43 0.1973 0.4319 3131572 CMLD2_000028 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B08 compound treatment 125600.0 14300.0 1.32 126400.0 16600.0 1.54 2.0245 0.997 3010203 CMLD2_000029 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B09 compound treatment 114000.0 2750.0 0.25 124000.0 14200.0 1.32 1.1127 0.8275 3010205 CMLD2_000030 COC(=O)NC/C=C\c1nc(CC/C=C\C(=O)OC)co1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B10 compound treatment 113600.0 2350.0 0.22 112400.0 2650.0 0.25 0.3264 0.998 3131573 CMLD2_000031 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@H](O)c2c(=O)o1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B11 compound treatment 122000.0 10700.0 0.99 114400.0 4650.0 0.43 1.0038 0.9307 3010207 CMLD2_000032 CC1(C)OCC(CO1)C(O)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B12 compound treatment 116000.0 4750.0 0.44 119600.0 9850.0 0.91 0.9544 0.9431 3131574 CMLD2_000033 COC(=O)[C@H](C)NC(=O)[C@@H](C)CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B13 mock treatment 118000.0 6750.0 0.62 120000.0 10200.0 0.95 1.1107 0.9788 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B14 mock treatment 110000.0 -1250.0 -0.12 124400.0 14600.0 1.36 0.8787 0.6449 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B15 compound treatment 112000.0 749.0 0.07 114000.0 4250.0 0.39 0.3272 0.8184 3010209 CMLD2_000034 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B16 compound treatment 109200.0 -2050.0 -0.19 116800.0 7050.0 0.65 0.3285 0.4832 2082484 CMLD2_000035 COC(=O)C(C1CCCC(=O)C1)C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B17 compound treatment 119600.0 8350.0 0.77 113200.0 3450.0 0.32 0.769 0.9245 3131575 CMLD2_000036 COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B18 mock treatment 108400.0 -2850.0 -0.26 116400.0 6650.0 0.62 0.2503 0.3738 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B19 compound treatment 122400.0 11100.0 1.03 114800.0 5050.0 0.47 1.056 0.9368 3010212 CMLD2_000037 CO[C@@H]1[C@H](O)CO[C@H]1/C=C/c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B20 compound treatment 113200.0 1950.0 0.18 114400.0 4650.0 0.43 0.4314 0.9245 3131576 CMLD2_000038 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B21 compound treatment 120800.0 9550.0 0.88 120000.0 10200.0 0.95 1.2928 0.9992 3010215 CMLD2_000039 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B22 compound treatment 119200.0 7950.0 0.73 110800.0 1050.0 0.1 0.5857 0.7941 3131577 CMLD2_000040 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B23 compound treatment 122400.0 11100.0 1.03 118800.0 9050.0 0.84 1.3182 0.995 3010186 CMLD2_000041 COc1ccc(cc1)c2ccccc2[C@@H]3N[C@@H](CC[C@H]3C)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 B24 compound treatment 114800.0 3550.0 0.33 122800.0 13000.0 1.21 1.086 0.867 3131578 CMLD2_000042 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCOC4=O)C(=O)CC)c5ccccc5)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C01 compound treatment 110800.0 -451.0 -0.04 109600.0 -152.0 -0.01 -0.0393 -0.8971 3131579 CMLD2_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C02 compound treatment 112800.0 1550.0 0.14 112800.0 3050.0 0.28 0.3005 0.9498 3010248 CMLD2_000044 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C03 compound treatment 110800.0 -451.0 -0.04 105200.0 -4550.0 -0.42 -0.3277 -0.7729 3131580 CMLD2_000045 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C04 compound treatment 113600.0 2350.0 0.22 112400.0 2650.0 0.25 0.3264 0.998 3131581 CMLD2_000046 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C05 compound treatment 122800.0 11500.0 1.06 118400.0 8650.0 0.8 1.318 0.9904 3131582 CMLD2_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C06 compound treatment 109600.0 -1650.0 -0.15 111200.0 1450.0 0.13 -0.0125 -0.0615 3010252 CMLD2_000048 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C07 compound treatment 110800.0 -451.0 -0.04 112400.0 2650.0 0.25 0.1442 0.5795 3131583 CMLD2_000049 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C08 compound treatment 111600.0 349.0 0.03 107200.0 -2550.0 -0.24 -0.1446 -0.6055 3010254 CMLD2_000050 Cc1cc2N(CC(O)CN3CCCc4nc(C)c(C)cc34)CCCc2nc1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C09 compound treatment 100000.0 -11300.0 -1.03 100800.0 -8950.0 -0.83 -1.3185 -0.994 3131584 CMLD2_000051 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C10 compound treatment 114400.0 3150.0 0.29 120400.0 10600.0 0.99 0.9027 0.8776 3010257 CMLD2_000052 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@@H](O)c2c(=O)o1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C11 mock treatment 116000.0 4750.0 0.44 106000.0 -3750.0 -0.35 0.063 0.1128 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C12 mock treatment 110400.0 -851.0 -0.08 114800.0 5050.0 0.47 0.2755 0.5808 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C13 compound treatment 112000.0 749.0 0.07 123600.0 13800.0 1.28 0.9564 0.744 3010259 CMLD2_000053 OC(CCOCc1ccccc1)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C14 compound treatment 98000.0 -13300.0 -1.22 100000.0 -9750.0 -0.9 -1.501 -0.9892 1304363 CMLD2_000054 C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C15 mock treatment 106800.0 -4450.0 -0.41 104000.0 -5750.0 -0.53 -0.6665 -0.9915 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C16 mock treatment 114000.0 2750.0 0.25 107600.0 -2150.0 -0.2 0.0378 0.1173 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C17 compound treatment 74400.0 -36900.0 -3.39 73200.0 -36600.0 -3.39 -4.7926 -1.0 3010233 CMLD2_000055 COc1ccc(cc1)c2cnnc(CCCn3ccnc3c4ccccc4)n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C18 compound treatment 92000.0 -19300.0 -1.77 98400.0 -11400.0 -1.05 -1.9962 -0.9691 3131585 CMLD2_000056 Cc1ccc(O[C@H]2C=C[C@@H](CC=C)O[C@@H]2COC(=O)NCc3cccc4ccccc34)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C19 compound treatment 110000.0 -1250.0 -0.12 111600.0 1850.0 0.17 0.0398 0.1927 3131586 CMLD2_000057 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2ccc(cc2)C(=O)OC)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C20 compound treatment 107200.0 -4050.0 -0.37 113600.0 3850.0 0.36 -0.0113 -0.0218 3010236 CMLD2_000058 C[C@H]1CC[C@@H]2N(CC(CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C21 compound treatment 115200.0 3950.0 0.36 124400.0 14600.0 1.36 1.2169 0.8658 3131587 CMLD2_000059 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2CC1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C22 compound treatment 116400.0 5150.0 0.47 121200.0 11400.0 1.06 1.0852 0.9339 3131703 CMLD2_000060 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C23 compound treatment 121600.0 10300.0 0.95 119200.0 9450.0 0.88 1.2924 0.9991 3010240 CMLD2_000061 OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 C24 compound treatment 110400.0 -851.0 -0.08 112000.0 2250.0 0.21 0.092 0.4134 3131704 CMLD2_000062 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C4=O)c5ccccc5)C(=O)OC)c6ccccc6)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D01 compound treatment 117600.0 6350.0 0.58 116800.0 7050.0 0.65 0.8749 0.9984 3010292 CMLD2_000063 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D02 compound treatment 110000.0 -1250.0 -0.12 110400.0 648.0 0.06 -0.0389 -0.2996 3131705 CMLD2_000064 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D03 compound treatment 108400.0 -2850.0 -0.26 108800.0 -952.0 -0.09 -0.2478 -0.8957 3131706 CMLD2_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D04 compound treatment 115200.0 3950.0 0.36 113200.0 3450.0 0.32 0.4829 0.998 3010296 CMLD2_000066 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D05 compound treatment 118000.0 6750.0 0.62 120400.0 10600.0 0.99 1.1369 0.975 3010274 CMLD2_000067 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D06 compound treatment 106000.0 -5250.0 -0.48 106400.0 -3350.0 -0.31 -0.5612 -0.9772 3131707 CMLD2_000068 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D07 compound treatment 101200.0 -10100.0 -0.92 97200.0 -12600.0 -1.16 -1.4764 -0.9935 3131708 CMLD2_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D08 compound treatment 119600.0 8350.0 0.77 121200.0 11400.0 1.06 1.2934 0.9874 3010278 CMLD2_000070 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D09 compound treatment 105200.0 -6050.0 -0.56 107200.0 -2550.0 -0.24 -0.5608 -0.9274 3010279 CMLD2_000071 CN1CCN(CC(O)CN2CCCc3nc(C)c(C)cc23)CC1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D10 compound treatment 117600.0 6350.0 0.58 104800.0 -4950.0 -0.46 0.0884 0.119 3131709 CMLD2_000072 C[C@@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D11 mock treatment 101600.0 -9650.0 -0.89 110400.0 648.0 0.06 -0.5852 -0.6578 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D12 mock treatment 111200.0 -50.7 0.0 104000.0 -5750.0 -0.53 -0.3803 -0.7133 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D13 compound treatment 114400.0 3150.0 0.29 112800.0 3050.0 0.28 0.4046 0.9999 3010281 CMLD2_000073 Brc1ccc(cc1)C(=O)OC(CCc2ccccc2)C3=CCCCC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D14 compound treatment 109200.0 -2050.0 -0.19 105600.0 -4150.0 -0.38 -0.4055 -0.9461 3131710 CMLD2_000074 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D15 mock treatment 109200.0 -2050.0 -0.19 103200.0 -6550.0 -0.61 -0.5628 -0.885 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D16 mock treatment 110400.0 -851.0 -0.08 104000.0 -5750.0 -0.53 -0.4323 -0.8023 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D17 compound treatment 113200.0 1950.0 0.18 108000.0 -1750.0 -0.16 0.012 0.0494 3131711 CMLD2_000075 COC(=O)C/C=C/[C@H](C)[C@H](CO)NS(=O)(=O)c1ccc(C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D18 compound treatment 110400.0 -851.0 -0.08 106400.0 -3350.0 -0.31 -0.275 -0.8584 3010283 CMLD2_000076 CCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D19 compound treatment 124800.0 13500.0 1.25 123600.0 13800.0 1.28 1.7889 0.9999 3131712 CMLD2_000077 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D20 compound treatment 113200.0 1950.0 0.18 112800.0 3050.0 0.28 0.3266 0.9759 3010285 CMLD2_000078 COC(=O)[C@@H]1CC[C@@H](C)[C@@H](N1)c2ccc(Br)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D21 compound treatment 115600.0 4350.0 0.4 113200.0 3450.0 0.32 0.5089 0.9938 3131713 CMLD2_000079 C[C@@H]1Cc2c(CO1)cnc3CCN(C)Cc32 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D22 compound treatment 110800.0 -451.0 -0.04 105200.0 -4550.0 -0.42 -0.3277 -0.7729 3131714 CMLD2_000080 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D23 compound treatment 122000.0 10700.0 0.99 113600.0 3850.0 0.36 0.9514 0.9051 3010288 CMLD2_000081 COc1cc(cc(OC)c1OC)[C@@H]2N[C@@H](Cc3c2[nH]c4ccccc34)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 D24 compound treatment 110000.0 -1250.0 -0.12 115600.0 5850.0 0.54 0.3019 0.5449 3131715 CMLD2_000082 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E01 mock treatment 110800.0 -451.0 -0.04 118000.0 8250.0 0.76 0.5113 0.6678 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E02 mock treatment 114000.0 2750.0 0.25 116400.0 6650.0 0.62 0.6145 0.9226 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E03 compound treatment 108000.0 -3250.0 -0.3 100800.0 -8950.0 -0.83 -0.7982 -0.905 3010304 CMLD2_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E04 compound treatment 116800.0 5550.0 0.51 109600.0 -152.0 -0.01 0.351 0.6873 3131716 CMLD2_000084 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E05 compound treatment 116000.0 4750.0 0.44 108800.0 -952.0 -0.09 0.2465 0.5531 3131717 CMLD2_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E06 compound treatment 98800.0 -12500.0 -1.15 102400.0 -7350.0 -0.68 -1.2917 -0.9692 3010306 CMLD2_000086 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E07 compound treatment 112400.0 1150.0 0.11 104000.0 -5750.0 -0.53 -0.3023 -0.5561 3131718 CMLD2_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E08 compound treatment 103600.0 -7650.0 -0.7 95600.0 -14200.0 -1.31 -1.4252 -0.9574 3131719 CMLD2_000088 Brc1ccc(cc1)c2ccc3N(CCCc3n2)C(=O)NCCCN4=CC=NC4c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E09 mock treatment 108800.0 -2450.0 -0.23 101600.0 -8150.0 -0.76 -0.6937 -0.8797 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E10 mock treatment 104400.0 -6850.0 -0.63 101200.0 -8550.0 -0.79 -1.0061 -0.9935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E11 compound treatment 96000.0 -15300.0 -1.4 86400.0 -23400.0 -2.16 -2.5225 -0.978 3010320 CMLD2_000089 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)NCc3cccc4ccccc34)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E12 compound treatment 108000.0 -3250.0 -0.3 100800.0 -8950.0 -0.83 -0.7982 -0.905 3131720 CMLD2_000090 CC(C)C(=O)N[C@H]1CCCN1C(=O)/C=C/c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E13 compound treatment 112400.0 1150.0 0.11 104000.0 -5750.0 -0.53 -0.3023 -0.5561 3010323 CMLD2_000091 OC(COCc1ccccc1)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E14 compound treatment 112000.0 749.0 0.07 91600.0 -18200.0 -1.68 -1.141 -0.6776 3131721 CMLD2_000092 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3ccccc3O[C@]2([C@@H]1c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E15 compound treatment 138400.0 27100.0 2.5 134000.0 24200.0 2.25 3.3551 0.9986 3010326 CMLD2_000093 COc1cc(O)c(C(=O)/C=C/c2ccc3OCOc3c2)c(OC)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E16 mock treatment 106000.0 -5250.0 -0.48 106000.0 -3750.0 -0.35 -0.5874 -0.987 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E17 mock treatment 107200.0 -4050.0 -0.37 102800.0 -6950.0 -0.64 -0.7191 -0.9661 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E18 mock treatment 113200.0 1950.0 0.18 107200.0 -2550.0 -0.24 -0.0405 -0.1364 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E19 compound treatment 99200.0 -12100.0 -1.11 96400.0 -13400.0 -1.24 -1.6589 -0.9985 3131722 CMLD2_000094 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E20 compound treatment 107200.0 -4050.0 -0.37 112400.0 2650.0 0.25 -0.0899 -0.2015 3131840 CMLD2_000095 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)C(F)(F)F)c2ccc(Br)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E21 compound treatment 110000.0 -1250.0 -0.12 104800.0 -4950.0 -0.46 -0.4059 -0.8578 3010332 CMLD2_000096 C1Cc2nc(c3ccccc3)c(cc2CN1)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E22 compound treatment 109600.0 -1650.0 -0.15 114800.0 5050.0 0.47 0.2235 0.4543 3131841 CMLD2_000097 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCOC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E23 compound treatment 121200.0 9950.0 0.92 114000.0 4250.0 0.39 0.9255 0.929 3010340 CMLD2_000098 C[C@H]1CC[C@H](N[C@@H]1c2cccc(CC=C)c2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 E24 compound treatment 125200.0 13900.0 1.28 116800.0 7050.0 0.65 1.3692 0.951 3131842 CMLD2_000099 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCCC4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F01 mock treatment 101200.0 -10100.0 -0.92 102800.0 -6950.0 -0.64 -1.1094 -0.9844 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F02 mock treatment 108000.0 -3250.0 -0.3 107200.0 -2550.0 -0.24 -0.3787 -0.9933 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F03 compound treatment 108000.0 -3250.0 -0.3 103200.0 -6550.0 -0.61 -0.6409 -0.9467 3131843 CMLD2_000100 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F04 compound treatment 99200.0 -12100.0 -1.11 100000.0 -9750.0 -0.9 -1.423 -0.9949 3010347 CMLD2_000101 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F05 compound treatment 103600.0 -7650.0 -0.7 103200.0 -6550.0 -0.61 -0.9271 -0.9973 3131844 CMLD2_000102 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F06 compound treatment 104000.0 -7250.0 -0.67 105200.0 -4550.0 -0.42 -0.77 -0.9756 3131845 CMLD2_000103 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F07 compound treatment 106000.0 -5250.0 -0.48 105200.0 -4550.0 -0.42 -0.6399 -0.9977 3011245 CMLD2_000104 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F08 compound treatment 107200.0 -4050.0 -0.37 99600.0 -10200.0 -0.94 -0.9289 -0.9178 3010203 CMLD2_000105 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F09 mock treatment 100000.0 -11300.0 -1.03 106400.0 -3350.0 -0.31 -0.9515 -0.8806 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F10 mock treatment 101600.0 -9650.0 -0.89 100000.0 -9750.0 -0.9 -1.2669 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F11 compound treatment 108800.0 -2450.0 -0.23 102800.0 -6950.0 -0.64 -0.6151 -0.9009 3011246 CMLD2_000106 C[C@@]12CCC3C(CCc4cc(OCC5CO5)ccc34)C2CC[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F12 compound treatment 92000.0 -19300.0 -1.77 88400.0 -21400.0 -1.98 -2.6516 -0.9985 3011247 CMLD2_000107 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F13 compound treatment 89200.0 -22100.0 -2.03 89600.0 -20200.0 -1.87 -2.755 -0.9992 3131846 CMLD2_000108 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F14 compound treatment 96800.0 -14500.0 -1.33 94000.0 -15800.0 -1.46 -1.9723 -0.9989 3011248 CMLD2_000109 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F15 compound treatment 113600.0 2350.0 0.22 107600.0 -2150.0 -0.2 0.0118 0.04 1946418 CMLD2_000110 Fc1ccc(cc1)C(=O)/C=C/c2ccc3OCOc3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F16 compound treatment 73600.0 -37700.0 -3.46 71200.0 -38600.0 -3.57 -4.9757 -0.9999 3011250 CMLD2_000111 OC(CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F17 mock treatment 110400.0 -851.0 -0.08 102000.0 -7750.0 -0.72 -0.5634 -0.7795 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F18 mock treatment 99200.0 -12100.0 -1.11 99200.0 -10600.0 -0.98 -1.4754 -0.9981 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F19 compound treatment 100400.0 -10900.0 -1.0 100400.0 -9350.0 -0.87 -1.3187 -0.9975 3131847 CMLD2_000112 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F20 compound treatment 102400.0 -8850.0 -0.81 101200.0 -8550.0 -0.79 -1.1362 -0.9999 3131848 CMLD2_000113 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1)c2ccc(Br)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F21 compound treatment 111600.0 349.0 0.03 104800.0 -4950.0 -0.46 -0.3019 -0.656 3011251 CMLD2_000114 CN1CCc2nc(CO)c(CO)cc2C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F22 compound treatment 109200.0 -2050.0 -0.19 109600.0 -152.0 -0.01 -0.1434 -0.7578 3131849 CMLD2_000115 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F23 compound treatment 108400.0 -2850.0 -0.26 110400.0 648.0 0.06 -0.143 -0.5314 3011252 CMLD2_000116 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(c3)N4CCOCC4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6cccc(c6)N7CCOCC7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 F24 compound treatment 112400.0 1150.0 0.11 110000.0 248.0 0.02 0.091 0.8412 3131850 CMLD2_000117 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C)C4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G01 compound treatment 110800.0 -451.0 -0.04 118800.0 9050.0 0.84 0.5637 0.6713 3131851 CMLD2_000118 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G02 compound treatment 110400.0 -851.0 -0.08 113600.0 3850.0 0.36 0.1969 0.5391 3131852 CMLD2_000119 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G03 mock treatment 105600.0 -5650.0 -0.52 115200.0 5450.0 0.5 -0.0105 -0.0144 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G04 mock treatment 104000.0 -7250.0 -0.67 106800.0 -2950.0 -0.27 -0.6651 -0.9226 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G05 compound treatment 110400.0 -851.0 -0.08 99600.0 -10200.0 -0.94 -0.7207 -0.7633 3011253 CMLD2_000120 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G06 compound treatment 109200.0 -2050.0 -0.19 102000.0 -7750.0 -0.72 -0.6415 -0.8635 3131853 CMLD2_000121 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G07 compound treatment 112400.0 1150.0 0.11 99200.0 -10600.0 -0.98 -0.6169 -0.627 3011254 CMLD2_000122 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)OC2CC(CCC3CC(=NO3)CC)OC4(CCCC(COC(=O)NCCC(C)C)O4)C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G08 compound treatment 99600.0 -11700.0 -1.07 94800.0 -15000.0 -1.39 -1.7378 -0.9919 3131854 CMLD2_000123 Cc1ccc(cc1)S(=O)(=O)NC(CCc2ccccc2)CC(=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G09 compound treatment 99600.0 -11700.0 -1.07 103600.0 -6150.0 -0.57 -1.161 -0.9564 3131855 CMLD2_000124 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)N3CCCCC3)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G10 compound treatment 107600.0 -3650.0 -0.34 105200.0 -4550.0 -0.42 -0.5358 -0.9936 3011255 CMLD2_000125 O[C@H]1C=C(C=C)C2(OCCCO2)[C@H]3O[C@H]31 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G11 compound treatment 97600.0 -13700.0 -1.26 100400.0 -9350.0 -0.87 -1.5008 -0.9836 3011256 CMLD2_000126 OC(CCc1ccccc1)C2=CCCOC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G12 compound treatment 113200.0 1950.0 0.18 130000.0 20200.0 1.88 1.4539 0.7712 3131856 CMLD2_000127 C[C@H]1OC=C2[C@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](OC(=O)C)[C@H]7O[C@H]7C6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G13 compound treatment 103600.0 -7650.0 -0.7 106000.0 -3750.0 -0.35 -0.7435 -0.9472 3011257 CMLD2_000128 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G14 compound treatment 114400.0 3150.0 0.29 111200.0 1450.0 0.13 0.2997 0.9388 3131857 CMLD2_000129 CC/C=C\CCC(OC(=O)c1ccc(Br)cc1)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G15 compound treatment 138000.0 26700.0 2.46 147600.0 37800.0 3.51 4.2205 0.9849 3011258 CMLD2_000130 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G16 mock treatment 118000.0 6750.0 0.62 115600.0 5850.0 0.54 0.8223 0.9977 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G17 compound treatment 104800.0 -6450.0 -0.59 103200.0 -6550.0 -0.61 -0.849 -0.9999 3131858 CMLD2_000131 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G18 compound treatment 111200.0 -50.7 0.0 100800.0 -8950.0 -0.83 -0.59 -0.7111 3131859 CMLD2_000132 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCCc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G19 mock treatment 110400.0 -851.0 -0.08 111600.0 1850.0 0.17 0.0658 0.3493 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G20 mock treatment 106000.0 -5250.0 -0.48 108400.0 -1350.0 -0.13 -0.4301 -0.862 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G21 compound treatment 116000.0 4750.0 0.44 108800.0 -952.0 -0.09 0.2465 0.5531 3011259 CMLD2_000133 CN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G22 compound treatment 113200.0 1950.0 0.18 108000.0 -1750.0 -0.16 0.012 0.0494 3131977 CMLD2_000134 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G23 compound treatment 82400.0 -28900.0 -2.65 56400.0 -53400.0 -4.95 -5.3733 -0.9574 3011260 CMLD2_000135 C[C@H]1CC[C@@H]2N([C@@H]1c3cccc(CC=C)c3)C(=O)[C@@H]4CC[C@H](C)[C@H](N4C2=O)c5cccc(CC=C)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 G24 compound treatment 121200.0 9950.0 0.92 119600.0 9850.0 0.91 1.2926 1.0 3131978 CMLD2_000136 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H01 compound treatment 114400.0 3150.0 0.29 109200.0 -552.0 -0.05 0.1687 0.5733 3131979 CMLD2_000137 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H02 compound treatment 110400.0 -851.0 -0.08 114800.0 5050.0 0.47 0.2755 0.5808 3131980 CMLD2_000138 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H03 mock treatment 117200.0 5950.0 0.55 118800.0 9050.0 0.84 0.98 0.9786 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H04 mock treatment 111600.0 349.0 0.03 110400.0 648.0 0.06 0.0652 0.9571 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H05 compound treatment 113600.0 2350.0 0.22 113200.0 3450.0 0.32 0.3788 0.9818 3011261 CMLD2_000139 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H06 compound treatment 103200.0 -8050.0 -0.74 106000.0 -3750.0 -0.35 -0.7696 -0.9406 3131981 CMLD2_000140 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H07 compound treatment 108800.0 -2450.0 -0.23 103200.0 -6550.0 -0.61 -0.5888 -0.909 3422360 CMLD2_000141 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H08 compound treatment 113600.0 2350.0 0.22 115200.0 5450.0 0.5 0.5099 0.9283 3010278 CMLD2_000142 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H09 compound treatment 116800.0 5550.0 0.51 126000.0 16200.0 1.51 1.4259 0.8967 3011262 CMLD2_000143 CON(C)C(=O)c1nnc2c3ccccc3[nH]c2n1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H10 compound treatment 113600.0 2350.0 0.22 112400.0 2650.0 0.25 0.3264 0.998 3011263 CMLD2_000144 C/C=C/C1=C(CO)C(=O)[C@@H]2O[C@@H]2C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H11 compound treatment 107600.0 -3650.0 -0.34 98000.0 -11800.0 -1.09 -1.0077 -0.884 3011264 CMLD2_000145 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H12 compound treatment 110800.0 -451.0 -0.04 110800.0 1050.0 0.1 0.0394 0.3728 3131982 CMLD2_000146 CCOC(=O)C1=NO[C@@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H13 compound treatment 104800.0 -6450.0 -0.59 101200.0 -8550.0 -0.79 -0.9801 -0.9898 3011265 CMLD2_000147 OC(C1CCCCC1)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H14 compound treatment 98000.0 -13300.0 -1.22 100800.0 -8950.0 -0.83 -1.4486 -0.9824 3011266 CMLD2_000148 OC(C1=CCCCC1=O)c2ccc(cc2)[N+](=O)[O-] 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H15 compound treatment 99200.0 -12100.0 -1.11 103600.0 -6150.0 -0.57 -1.187 -0.9523 3131983 CMLD2_000149 CC1(C)O[C@H]2OC([C@H](O)CON3C(=O)c4ccccc4C3=O)[C@H](O)[C@H]2O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H16 compound treatment 62000.0 -49300.0 -4.53 60400.0 -49400.0 -4.57 -6.438 -1.0 3011267 CMLD2_000150 COCOc1ccc(Br)cc1C(=O)[C@@H]2O[C@H]2c3cccc(OC)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H17 compound treatment 124000.0 12700.0 1.17 115600.0 5850.0 0.54 1.2125 0.9385 3131984 CMLD2_000151 C[C@@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@]42[C@H]5O[C@H](C)[C@@H]([C@@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H18 compound treatment 138000.0 26700.0 2.46 112800.0 3050.0 0.28 1.9396 0.7831 3011268 CMLD2_000152 COc1ccc(C#C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H19 mock treatment 110000.0 -1250.0 -0.12 105200.0 -4550.0 -0.42 -0.3797 -0.8682 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H20 mock treatment 116000.0 4750.0 0.44 104400.0 -5350.0 -0.5 -0.0419 -0.0634 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H21 compound treatment 113200.0 1950.0 0.18 105600.0 -4150.0 -0.38 -0.1454 -0.3423 3131985 CMLD2_000153 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H22 compound treatment 113200.0 1950.0 0.18 107200.0 -2550.0 -0.24 -0.0405 -0.1364 3131715 CMLD2_000154 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H23 compound treatment 111200.0 -50.7 0.0 109200.0 -552.0 -0.05 -0.0395 -0.7684 3011247 CMLD2_000155 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 H24 compound treatment 117600.0 6350.0 0.58 125200.0 15400.0 1.43 1.4255 0.9218 3131986 CMLD2_000156 COC(=O)C1=C(C)N(Cc2ccccc2)c3c(C(=O)OC)c(C(=O)OC)c(C(=O)OC)c(=O)n3[C@@H]1c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I01 compound treatment 117600.0 6350.0 0.58 118000.0 8250.0 0.76 0.9536 0.9912 3131987 CMLD2_000157 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I02 compound treatment 108000.0 -3250.0 -0.3 112800.0 3050.0 0.28 -0.0117 -0.0284 3011269 CMLD2_000158 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I03 compound treatment 119600.0 8350.0 0.77 122000.0 12200.0 1.14 1.3458 0.9819 3131988 CMLD2_000159 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I04 compound treatment 112800.0 1550.0 0.14 108400.0 -1350.0 -0.13 0.0121 0.064 3011270 CMLD2_000160 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I05 mock treatment 122000.0 10700.0 0.99 110800.0 1050.0 0.1 0.7678 0.7728 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I06 mock treatment 110000.0 -1250.0 -0.12 110800.0 1050.0 0.1 -0.0127 -0.0841 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I07 compound treatment 111200.0 -50.7 0.0 110800.0 1050.0 0.1 0.0654 0.6724 3422373 CMLD2_000161 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I08 compound treatment 107200.0 -4050.0 -0.37 113200.0 3450.0 0.32 -0.0375 -0.0764 3011271 CMLD2_000162 COC(=O)NC/C=C\c1nc(CCCO)co1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I09 compound treatment 102000.0 -9250.0 -0.85 95200.0 -14600.0 -1.35 -1.5555 -0.9753 3131989 CMLD2_000163 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I10 compound treatment 100400.0 -10900.0 -1.0 102000.0 -7750.0 -0.72 -1.2138 -0.987 3011272 CMLD2_000164 CO[C@@H]1[C@@H](C)/C(=C\CC(=O)OC)/c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I11 compound treatment 104000.0 -7250.0 -0.67 103200.0 -6550.0 -0.61 -0.901 -0.9989 3131990 CMLD2_000165 CC(=NOCc1ccc(cc1)c2cc(no2)c3ccccc3)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I12 compound treatment 107200.0 -4050.0 -0.37 100000.0 -9750.0 -0.9 -0.9026 -0.9232 3131991 CMLD2_000166 COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I13 compound treatment 108400.0 -2850.0 -0.26 102000.0 -7750.0 -0.72 -0.6935 -0.9067 3011273 CMLD2_000167 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I14 compound treatment 97600.0 -13700.0 -1.26 88400.0 -21400.0 -1.98 -2.2873 -0.9759 3131992 CMLD2_000168 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#Cc3ccccc3)cc2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I15 compound treatment 109200.0 -2050.0 -0.19 96800.0 -13000.0 -1.2 -0.9823 -0.8083 3011274 CMLD2_000169 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I16 mock treatment 108400.0 -2850.0 -0.26 102000.0 -7750.0 -0.72 -0.6935 -0.9067 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I17 compound treatment 119200.0 7950.0 0.73 83200.0 -26600.0 -2.46 -1.2232 -0.4764 3131993 CMLD2_000170 C[C@H]1OC=C2[C@H](O)C3O[C@@H]3/C(=N\OCc4ccccc4)/[C@@]52[C@H]6OC(C)[C@@H](C15)C7=C6[C@H](O)[C@H]8O[C@H]8C7=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I18 compound treatment 112800.0 1550.0 0.14 104400.0 -5350.0 -0.5 -0.25 -0.4844 3011312 CMLD2_000171 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I19 compound treatment 118000.0 6750.0 0.62 107200.0 -2550.0 -0.24 0.2717 0.409 3131989 CMLD2_000172 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I20 compound treatment 114800.0 3550.0 0.33 109600.0 -152.0 -0.01 0.2209 0.6759 3011257 CMLD2_000173 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I21 mock treatment 112400.0 1150.0 0.11 110000.0 248.0 0.02 0.091 0.8412 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I22 mock treatment 121600.0 10300.0 0.95 114000.0 4250.0 0.39 0.9516 0.9237 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I23 compound treatment 124800.0 13500.0 1.25 124800.0 15000.0 1.39 1.8675 0.9984 3132111 CMLD2_000174 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(NC(=O)C)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(NC(=O)C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 I24 compound treatment 118800.0 7550.0 0.69 125600.0 15800.0 1.47 1.5297 0.9415 3131703 CMLD2_000175 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J01 compound treatment 104800.0 -6450.0 -0.59 112400.0 2650.0 0.25 -0.246 -0.3831 3132112 CMLD2_000176 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J02 compound treatment 114000.0 2750.0 0.25 112800.0 3050.0 0.28 0.3786 0.9985 3011347 CMLD2_000177 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J03 compound treatment 122400.0 11100.0 1.03 112800.0 3050.0 0.28 0.9249 0.8695 3132113 CMLD2_000178 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J04 compound treatment 108800.0 -2450.0 -0.23 97600.0 -12200.0 -1.13 -0.9559 -0.8321 3132114 CMLD2_000179 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J05 mock treatment 111600.0 349.0 0.03 109600.0 -152.0 -0.01 0.0127 0.3634 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J06 mock treatment 110400.0 -851.0 -0.08 110400.0 648.0 0.06 -0.0129 -0.1305 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J07 compound treatment 107200.0 -4050.0 -0.37 106800.0 -2950.0 -0.27 -0.457 -0.9885 3011348 CMLD2_000180 CC(C)C[C@H](NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J08 compound treatment 67600.0 -43700.0 -4.02 67600.0 -42200.0 -3.91 -5.6019 -0.9999 3132115 CMLD2_000181 CO[C@H]1C[C@@H]2C[C@H](CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2)OC(=O)\C=C/CCc4coc(\C=C/CNC(=O)OC)n4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J09 compound treatment 104000.0 -7250.0 -0.67 98000.0 -11800.0 -1.09 -1.2419 -0.9723 3011349 CMLD2_000182 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J10 compound treatment 107600.0 -3650.0 -0.34 103200.0 -6550.0 -0.61 -0.6669 -0.961 3132116 CMLD2_000183 CO[C@@H](C(C)C)[C@@H](C)C1OC(=O)CC1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J11 compound treatment 92000.0 -19300.0 -1.77 81600.0 -28200.0 -2.61 -3.0973 -0.9822 3132117 CMLD2_000184 COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@](Oc3ccccc3C1=O)(C(=O)OC)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J12 compound treatment 106400.0 -4850.0 -0.45 104400.0 -5350.0 -0.5 -0.6663 -0.9986 3011350 CMLD2_000185 CC(=NOCc1cccc(c1)c2cc(no2)c3ccccc3)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J13 compound treatment 103600.0 -7650.0 -0.7 105200.0 -4550.0 -0.42 -0.796 -0.9701 3132118 CMLD2_000186 CC(C)C(=O)N[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J14 compound treatment 105200.0 -6050.0 -0.56 105600.0 -4150.0 -0.38 -0.6657 -0.9838 3011352 CMLD2_000187 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C=C)cc2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J15 compound treatment 109600.0 -1650.0 -0.15 109600.0 -152.0 -0.01 -0.1173 -0.7695 3132119 CMLD2_000188 CO[C@H](CO)COc1ccc(OC)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J16 compound treatment 108400.0 -2850.0 -0.26 98000.0 -11800.0 -1.09 -0.9557 -0.853 3011353 CMLD2_000189 Oc1ccccc1C(=O)/C=C/c2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J17 compound treatment 118800.0 7550.0 0.69 120400.0 10600.0 0.99 1.1889 0.9852 3132120 CMLD2_000190 CC(=NOCc1ccc(cc1)c2cn(nn2)[C@@H]3COC[C@H]3O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J18 compound treatment 119200.0 7950.0 0.73 118000.0 8250.0 0.76 1.0576 0.9998 3011354 CMLD2_000191 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J19 compound treatment 110000.0 -1250.0 -0.12 112800.0 3050.0 0.28 0.1184 0.3882 3132121 CMLD2_000192 C[C@@H]1CC[C@@H]2N(CC(COCC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J20 compound treatment 111200.0 -50.7 0.0 111600.0 1850.0 0.17 0.1178 0.6876 3011355 CMLD2_000193 CC(C)CCN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J21 mock treatment 114000.0 2750.0 0.25 112000.0 2250.0 0.21 0.3262 0.9954 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J22 mock treatment 118000.0 6750.0 0.62 115200.0 5450.0 0.5 0.7961 0.9947 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J23 compound treatment 120400.0 9150.0 0.84 118400.0 8650.0 0.8 1.1619 0.9997 3132122 CMLD2_000194 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(Br)c3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5cccc(c5)N6CCOCC6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 J24 compound treatment 115200.0 3950.0 0.36 115200.0 5450.0 0.5 0.6139 0.9869 3132123 CMLD2_000195 CCC(=O)[C@@]1(O[C@@]23[C@H]4[C@@H]1CCOC4=O)C(=O)N3[C@@H](C(=C(C)N2Cc5ccccc5)C(=O)OC)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K01 compound treatment 114400.0 3150.0 0.29 117600.0 7850.0 0.73 0.7192 0.9185 3132124 CMLD2_000196 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K02 compound treatment 113200.0 1950.0 0.18 111600.0 1850.0 0.17 0.2479 0.9997 3011357 CMLD2_000197 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K03 compound treatment 116800.0 5550.0 0.51 114000.0 4250.0 0.39 0.6394 0.9918 3132125 CMLD2_000198 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K04 compound treatment 112000.0 749.0 0.07 117600.0 7850.0 0.73 0.5631 0.7707 3132126 CMLD2_000199 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K05 compound treatment 118400.0 7150.0 0.66 108400.0 -1350.0 -0.13 0.3764 0.5622 3011359 CMLD2_000200 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K06 compound treatment 108800.0 -2450.0 -0.23 102400.0 -7350.0 -0.68 -0.6413 -0.8934 3132127 CMLD2_000201 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K07 mock treatment 111600.0 349.0 0.03 110400.0 648.0 0.06 0.0652 0.9571 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K08 mock treatment 106000.0 -5250.0 -0.48 104400.0 -5350.0 -0.5 -0.6923 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K09 compound treatment 110400.0 -851.0 -0.08 101600.0 -8150.0 -0.76 -0.5896 -0.7762 3011360 CMLD2_000202 COc1cccc(c1)[C@H](O)Cn2cc(nn2)c3ccc(CON=C(C)C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K10 compound treatment 96800.0 -14500.0 -1.33 93200.0 -16600.0 -1.53 -2.0248 -0.9974 3132128 CMLD2_000203 Cc1ccc2[nH]c3nc(CCCn4ccnc4c5ccccc5)nnc3c2c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K11 compound treatment 99200.0 -12100.0 -1.11 95600.0 -14200.0 -1.31 -1.7114 -0.9965 3011361 CMLD2_000204 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@H](O1)c2c(OC)c(OC)c(C)c(OC)c2OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K12 compound treatment 60400.0 -50900.0 -4.68 102800.0 -6950.0 -0.64 -3.7631 -0.797 3132129 CMLD2_000205 C[C@H]1OC=C2[C@H](OC(=O)C)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](O)[C@H]7O[C@H]7C6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K13 compound treatment 105200.0 -6050.0 -0.56 105600.0 -4150.0 -0.38 -0.6657 -0.9838 3011362 CMLD2_000206 CO[C@H]1C[C@@H]2C[C@H](O)CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K14 compound treatment 139600.0 28300.0 2.61 131600.0 21800.0 2.03 3.2759 0.9922 3011258 CMLD2_000207 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K15 mock treatment 107200.0 -4050.0 -0.37 102400.0 -7350.0 -0.68 -0.7453 -0.9596 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K16 mock treatment 106000.0 -5250.0 -0.48 105600.0 -4150.0 -0.38 -0.6137 -0.9937 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K17 compound treatment 6400.0 -105000.0 -9.64 14400.0 -95400.0 -8.84 -13.0693 -0.999 3132248 CMLD2_000208 CCN1C(=O)[C@H]2CC=C3[C@H]([C@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C53OCCCO5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K18 compound treatment 104000.0 -7250.0 -0.67 96000.0 -13800.0 -1.27 -1.3729 -0.9543 3011363 CMLD2_000209 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K19 compound treatment 110400.0 -851.0 -0.08 112800.0 3050.0 0.28 0.1444 0.4927 3132249 CMLD2_000210 C[C@@H]1CC[C@@H]2N(CC(COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K20 compound treatment 109600.0 -1650.0 -0.15 101200.0 -8550.0 -0.79 -0.6679 -0.8275 3011399 CMLD2_000211 CCCCc1nc2CCN(CCC(C)C)Cc2c3CO[C@@H](C)Cc13 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K21 compound treatment 115200.0 3950.0 0.36 107200.0 -2550.0 -0.24 0.0896 0.2067 3132250 CMLD2_000212 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K22 compound treatment 117600.0 6350.0 0.58 116400.0 6650.0 0.62 0.8487 0.9996 3011400 CMLD2_000213 C[C@@H]1CC[C@H](N[C@H]1c2ccc(cc2)c3ccco3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K23 mock treatment 119200.0 7950.0 0.73 123600.0 13800.0 1.28 1.4247 0.9644 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 K24 mock treatment 109200.0 -2050.0 -0.19 123600.0 13800.0 1.28 0.7742 0.5968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L01 compound treatment 113600.0 2350.0 0.22 111200.0 1450.0 0.13 0.2477 0.9737 3132251 CMLD2_000214 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L02 compound treatment 110000.0 -1250.0 -0.12 110400.0 648.0 0.06 -0.0389 -0.2996 3132252 CMLD2_000215 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L03 compound treatment 118400.0 7150.0 0.66 113200.0 3450.0 0.32 0.691 0.9451 3011402 CMLD2_000216 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L04 compound treatment 115200.0 3950.0 0.36 111600.0 1850.0 0.17 0.378 0.9411 3132253 CMLD2_000217 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L05 compound treatment 115600.0 4350.0 0.4 105600.0 -4150.0 -0.38 0.0108 0.0194 3132254 CMLD2_000218 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L06 compound treatment 107200.0 -4050.0 -0.37 108800.0 -952.0 -0.09 -0.3259 -0.851 3011403 CMLD2_000219 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L07 mock treatment 116000.0 4750.0 0.44 100800.0 -8950.0 -0.83 -0.2778 -0.2963 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L08 mock treatment 118800.0 7550.0 0.69 113600.0 3850.0 0.36 0.7432 0.9521 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L09 compound treatment 116000.0 4750.0 0.44 107200.0 -2550.0 -0.24 0.1416 0.2851 3132255 CMLD2_000220 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L10 compound treatment 119600.0 8350.0 0.77 108800.0 -952.0 -0.09 0.4807 0.6218 3132256 CMLD2_000221 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(C)c(C)cc45)CCCc3n2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L11 compound treatment 111200.0 -50.7 0.0 97600.0 -12200.0 -1.13 -0.7998 -0.71 3011404 CMLD2_000222 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L12 compound treatment 96800.0 -14500.0 -1.33 109200.0 -552.0 -0.05 -0.9761 -0.7338 3011405 CMLD2_000223 OC(CCc1ccccc1)C2=CCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L13 compound treatment 112800.0 1550.0 0.14 97600.0 -12200.0 -1.13 -0.6957 -0.6128 3132257 CMLD2_000224 OC(CCc1ccccc1)C23OC3CCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L14 compound treatment 110400.0 -851.0 -0.08 100400.0 -9350.0 -0.87 -0.6683 -0.7678 3132258 CMLD2_000225 CCCNC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L15 mock treatment 108400.0 -2850.0 -0.26 112400.0 2650.0 0.25 -0.0119 -0.033 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L16 mock treatment 108400.0 -2850.0 -0.26 109200.0 -552.0 -0.05 -0.2216 -0.8295 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L17 compound treatment 109200.0 -2050.0 -0.19 99600.0 -10200.0 -0.94 -0.7988 -0.8323 3011407 CMLD2_000226 C[C@H]1CC[C@@H]2N([C@@H]1c3ccccc3)C(=O)[C@@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L18 compound treatment 105600.0 -5650.0 -0.52 63600.0 -46200.0 -4.28 -3.3924 -0.7872 3132259 CMLD2_000227 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L19 compound treatment 110400.0 -851.0 -0.08 107200.0 -2550.0 -0.24 -0.2226 -0.8934 3132260 CMLD2_000228 C[C@@H]1CC[C@@H]2N(CC(CN3C(=O)c4ccccc4C3=O)OC2=O)[C@H]1c5ccc(Br)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L20 compound treatment 120000.0 8750.0 0.8 103200.0 -6550.0 -0.61 0.1396 0.1385 3011408 CMLD2_000229 CC(C)CCN1CCc2nc(COc3ccccc3)c4C[C@H](C)OCc4c2C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L21 compound treatment 118000.0 6750.0 0.62 117600.0 7850.0 0.73 0.9534 0.9969 3132261 CMLD2_000230 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L22 compound treatment 111600.0 349.0 0.03 111600.0 1850.0 0.17 0.1438 0.8254 3011409 CMLD2_000231 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#CCN(C)C)cc2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L23 mock treatment 120400.0 9150.0 0.84 122000.0 12200.0 1.14 1.3978 0.9891 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 L24 mock treatment 124000.0 12700.0 1.17 127600.0 17800.0 1.65 1.999 0.9858 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M01 compound treatment 122400.0 11100.0 1.03 116000.0 6250.0 0.58 1.1347 0.9634 3132262 CMLD2_000232 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M02 compound treatment 115600.0 4350.0 0.4 107200.0 -2550.0 -0.24 0.1156 0.2488 3132263 CMLD2_000233 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M03 compound treatment 118800.0 7550.0 0.69 115600.0 5850.0 0.54 0.8743 0.9925 3011410 CMLD2_000234 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M04 compound treatment 114400.0 3150.0 0.29 111200.0 1450.0 0.13 0.2997 0.9388 3132264 CMLD2_000235 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M05 compound treatment 106800.0 -4450.0 -0.41 105600.0 -4150.0 -0.38 -0.5616 -0.9995 3132265 CMLD2_000236 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M06 compound treatment 112400.0 1150.0 0.11 109200.0 -552.0 -0.05 0.0386 0.3284 3011411 CMLD2_000237 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M07 compound treatment 103600.0 -7650.0 -0.7 106800.0 -2950.0 -0.27 -0.6911 -0.9153 3132266 CMLD2_000238 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M08 compound treatment 110000.0 -1250.0 -0.12 102400.0 -7350.0 -0.68 -0.5632 -0.8149 3011412 CMLD2_000239 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M09 mock treatment 107600.0 -3650.0 -0.34 108000.0 -1750.0 -0.16 -0.3523 -0.9444 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M10 mock treatment 106400.0 -4850.0 -0.45 109600.0 -152.0 -0.01 -0.3255 -0.7291 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M11 compound treatment 102000.0 -9250.0 -0.85 98400.0 -11400.0 -1.05 -1.3457 -0.9945 3132389 CMLD2_000240 COC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M12 compound treatment 111200.0 -50.7 0.0 109200.0 -552.0 -0.05 -0.0395 -0.7684 3011413 CMLD2_000241 O=C1CCCC(C1)C2=CCCCC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M13 mock treatment 106000.0 -5250.0 -0.48 111200.0 1450.0 0.13 -0.2466 -0.492 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M14 mock treatment 117200.0 5950.0 0.55 100800.0 -8950.0 -0.83 -0.1998 -0.201 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M15 compound treatment 110800.0 -451.0 -0.04 105600.0 -4150.0 -0.38 -0.3015 -0.7788 3132390 CMLD2_000242 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCCc2nc1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M16 compound treatment 112000.0 749.0 0.07 113600.0 3850.0 0.36 0.3009 0.8284 3011415 CMLD2_000243 CCO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M17 mock treatment 107600.0 -3650.0 -0.34 110800.0 1050.0 0.1 -0.1688 -0.4828 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M18 compound treatment 91200.0 -20100.0 -1.84 86400.0 -23400.0 -2.16 -2.8347 -0.9968 3132391 CMLD2_000244 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCC2CCCCC2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M19 compound treatment 111600.0 349.0 0.03 100000.0 -9750.0 -0.9 -0.6165 -0.6815 3132392 CMLD2_000245 C[C@@H]1CC[C@@H]2N(CC(Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M20 compound treatment 118800.0 7550.0 0.69 113200.0 3450.0 0.32 0.717 0.938 3011466 CMLD2_000246 COc1ccc(cc1)c2nc3CCN(CCC(C)C)Cc3c4CO[C@@H](C)Cc24 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M21 compound treatment 119200.0 7950.0 0.73 108400.0 -1350.0 -0.13 0.4284 0.5775 3132393 CMLD2_000247 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCOC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M22 compound treatment 114400.0 3150.0 0.29 124000.0 14200.0 1.32 1.1387 0.8422 3011467 CMLD2_000248 C[C@H]1CC[C@H](N[C@@H]1c2cccc(c2)N3CCCC3=O)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M23 compound treatment 114400.0 3150.0 0.29 119200.0 9450.0 0.88 0.8241 0.8934 3132394 CMLD2_000249 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 M24 compound treatment 113600.0 2350.0 0.22 115600.0 5850.0 0.54 0.5361 0.9187 3132261 CMLD2_000250 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N01 compound treatment 124800.0 13500.0 1.25 124800.0 15000.0 1.39 1.8675 0.9984 3132395 CMLD2_000251 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N02 compound treatment 102800.0 -8450.0 -0.78 110000.0 248.0 0.02 -0.5334 -0.6859 3132396 CMLD2_000252 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N03 compound treatment 118800.0 7550.0 0.69 116800.0 7050.0 0.65 0.953 0.9995 3011471 CMLD2_000253 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N04 compound treatment 122800.0 11500.0 1.06 122800.0 13000.0 1.21 1.6064 0.9979 3132397 CMLD2_000254 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N05 compound treatment 118000.0 6750.0 0.62 111600.0 1850.0 0.17 0.5601 0.8697 3011472 CMLD2_000255 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N06 compound treatment 110000.0 -1250.0 -0.12 104800.0 -4950.0 -0.46 -0.4059 -0.8578 3132398 CMLD2_000256 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N07 compound treatment 112000.0 749.0 0.07 118800.0 9050.0 0.84 0.6418 0.7626 3132399 CMLD2_000257 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N08 compound treatment 148800.0 37500.0 3.45 139600.0 29800.0 2.77 4.3986 0.994 3011473 CMLD2_000258 Cc1ccc(cc1)S(=O)(=O)n2c3ccccc3c4nnc(nc24)C(=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N09 mock treatment 113600.0 2350.0 0.22 108800.0 -952.0 -0.09 0.0904 0.3873 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N10 mock treatment 112400.0 1150.0 0.11 112000.0 2250.0 0.21 0.2221 0.9505 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N11 compound treatment 110400.0 -851.0 -0.08 108400.0 -1350.0 -0.13 -0.144 -0.9743 3011475 CMLD2_000259 BrC1=CC(=C)[C@@H]2O[C@@H]2C31OCCCO3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N12 compound treatment 104800.0 -6450.0 -0.59 108000.0 -1750.0 -0.16 -0.5344 -0.8687 3132400 CMLD2_000260 CCCCOC(OCCCC)C(O)CSc1ccc2ccccc2c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N13 mock treatment 108000.0 -3250.0 -0.3 110400.0 648.0 0.06 -0.169 -0.554 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N14 mock treatment 112000.0 749.0 0.07 106000.0 -3750.0 -0.35 -0.1972 -0.5562 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N15 compound treatment 106400.0 -4850.0 -0.45 103600.0 -6150.0 -0.57 -0.7187 -0.9926 3011477 CMLD2_000261 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N16 compound treatment 113600.0 2350.0 0.22 110400.0 648.0 0.06 0.1953 0.8706 3132401 CMLD2_000262 CO[C@@H](C(C)C)[C@@H](C)C1OC1CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N17 compound treatment 37600.0 -73700.0 -6.77 35200.0 -74600.0 -6.91 -9.6767 -1.0 4845 CMLD2_000263 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c4ccccc4)c5ccc(OC)cc5)cc(OC)cc3OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N18 compound treatment 110400.0 -851.0 -0.08 107600.0 -2150.0 -0.2 -0.1964 -0.9165 3011479 CMLD2_000264 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2cc(OC)c(OC)c(OC)c2)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N19 compound treatment 104800.0 -6450.0 -0.59 108000.0 -1750.0 -0.16 -0.5344 -0.8687 3132403 CMLD2_000265 C[C@H]1CC[C@@H]2N(CC(COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N20 compound treatment 112800.0 1550.0 0.14 108400.0 -1350.0 -0.13 0.0121 0.064 3011480 CMLD2_000266 C[C@H]1Cc2c(nc3CCN(CCOc4ccccc4)Cc3c2CO1)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N21 compound treatment 82400.0 -28900.0 -2.65 86400.0 -23400.0 -2.16 -3.4071 -0.9949 3132404 CMLD2_000267 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N22 compound treatment 126000.0 14700.0 1.36 121200.0 11400.0 1.06 1.7096 0.9926 3011481 CMLD2_000268 C[C@@H]1CC[C@H](N[C@H]1c2ccc(NC(=O)C)cc2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N23 compound treatment 128800.0 17500.0 1.61 128400.0 18600.0 1.73 2.3637 0.9994 3132405 CMLD2_000269 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@H](C(C)C)N(C)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 N24 compound treatment 126000.0 14700.0 1.36 112000.0 2250.0 0.21 1.1067 0.8062 3131577 CMLD2_000270 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O01 compound treatment 124400.0 13100.0 1.21 117200.0 7450.0 0.69 1.3434 0.9646 3132406 CMLD2_000271 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O02 compound treatment 121600.0 10300.0 0.95 108800.0 -952.0 -0.09 0.6107 0.6388 3132407 CMLD2_000272 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6ccc7OCOc7c6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O03 compound treatment 122400.0 11100.0 1.03 108800.0 -952.0 -0.09 0.6628 0.6439 3011482 CMLD2_000273 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O04 compound treatment 125200.0 13900.0 1.28 117200.0 7450.0 0.69 1.3954 0.9577 3132527 CMLD2_000274 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O05 compound treatment 114000.0 2750.0 0.25 102800.0 -6950.0 -0.64 -0.2768 -0.3999 3011483 CMLD2_000275 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O06 compound treatment 122400.0 11100.0 1.03 115600.0 5850.0 0.54 1.1085 0.9556 3132528 CMLD2_000276 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O07 compound treatment 109600.0 -1650.0 -0.15 98400.0 -11400.0 -1.05 -0.8514 -0.8008 3011485 CMLD2_000277 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O08 compound treatment 112800.0 1550.0 0.14 105600.0 -4150.0 -0.38 -0.1714 -0.4176 3132529 CMLD2_000278 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O09 compound treatment 118800.0 7550.0 0.69 116400.0 6650.0 0.62 0.9267 0.9982 3011486 CMLD2_000279 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2c(OC)c(OC)c(C)c(OC)c2OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O10 compound treatment 4000.0 -107000.0 -9.87 5600.0 -104000.0 -9.65 -13.8022 -0.9999 3132530 CMLD2_000280 OC(CCCCBr)C1=CCCCC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O11 mock treatment 120000.0 8750.0 0.8 105600.0 -4150.0 -0.38 0.2969 0.3329 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O12 mock treatment 110000.0 -1250.0 -0.12 109600.0 -152.0 -0.01 -0.0913 -0.7879 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O13 compound treatment 110000.0 -1250.0 -0.12 111600.0 1850.0 0.17 0.0398 0.1927 3132531 CMLD2_000281 COC(=O)C/C=C/[C@H](C)[C@@H](OCc1ccccc1Br)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O14 compound treatment 4000.0 -107000.0 -9.87 4000.0 -106000.0 -9.8 -13.9071 -1.0 3011535 CMLD2_000282 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O15 compound treatment 109600.0 -1650.0 -0.15 109200.0 -552.0 -0.05 -0.1436 -0.8959 3132532 CMLD2_000283 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O16 compound treatment 111600.0 349.0 0.03 114400.0 4650.0 0.43 0.3274 0.7577 3131858 CMLD2_000284 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O17 mock treatment 112000.0 749.0 0.07 107200.0 -2550.0 -0.24 -0.1185 -0.4811 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O18 compound treatment 131200.0 19900.0 1.84 133600.0 23800.0 2.21 2.8606 0.9957 3011536 CMLD2_000285 OC[C@H]1O[C@@H](C=C[C@@H]1O)C#Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O19 compound treatment 116800.0 5550.0 0.51 101600.0 -8150.0 -0.76 -0.1734 -0.1901 3132533 CMLD2_000286 C[C@H]1CC[C@@H]2N(C[C@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O20 compound treatment 108800.0 -2450.0 -0.23 111600.0 1850.0 0.17 -0.0383 -0.1352 3011537 CMLD2_000287 C[C@H]1Cc2c(COc3ccccc3)nc4CCN(CCOc5ccccc5)Cc4c2CO1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O21 compound treatment 114400.0 3150.0 0.29 109600.0 -152.0 -0.01 0.1949 0.6719 3132534 CMLD2_000288 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O22 compound treatment 124400.0 13100.0 1.21 118400.0 8650.0 0.8 1.4221 0.98 3011538 CMLD2_000289 C[C@@H]1CC[C@H](N[C@H]1c2cccc(c2)N3CCOCC3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O23 compound treatment 99200.0 -12100.0 -1.11 103200.0 -6550.0 -0.61 -1.2132 -0.9599 3132535 CMLD2_000290 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)c3ccccc3)c4ccccc4)C(=O)OC)c5ccccc5)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 O24 compound treatment 119200.0 7950.0 0.73 111200.0 1450.0 0.13 0.6119 0.8231 3132250 CMLD2_000291 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P01 compound treatment 121200.0 9950.0 0.92 123200.0 13400.0 1.25 1.5285 0.9885 3132536 CMLD2_000292 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P02 compound treatment 114000.0 2750.0 0.25 122400.0 12600.0 1.17 1.0078 0.8403 3132537 CMLD2_000293 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P03 compound treatment 107600.0 -3650.0 -0.34 107600.0 -2150.0 -0.2 -0.3785 -0.9691 3011540 CMLD2_000294 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P04 compound treatment 115600.0 4350.0 0.4 114400.0 4650.0 0.43 0.5875 0.9993 3132538 CMLD2_000295 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P05 compound treatment 122000.0 10700.0 0.99 113200.0 3450.0 0.32 0.9251 0.8903 3011541 CMLD2_000296 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P06 compound treatment 109600.0 -1650.0 -0.15 110000.0 248.0 0.02 -0.0911 -0.5933 3132539 CMLD2_000297 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P07 compound treatment 114000.0 2750.0 0.25 109200.0 -552.0 -0.05 0.1426 0.5528 3011542 CMLD2_000298 CCN(CC)CC(O)CN1CCCCc2nc(C)c(C)cc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P08 compound treatment 114800.0 3550.0 0.33 114800.0 5050.0 0.47 0.5617 0.9845 3131847 CMLD2_000299 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P09 compound treatment 140800.0 29500.0 2.72 134800.0 25000.0 2.32 3.5637 0.9969 3132540 CMLD2_000300 C[C@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5O[C@H](C)[C@@H]([C@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P10 compound treatment 27200.0 -84100.0 -7.73 26400.0 -83400.0 -7.73 -10.9299 -1.0 3011543 CMLD2_000301 COCOc1ccc(Br)cc1C(=O)/C=C/c2ccc3OCOc3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P11 mock treatment 112800.0 1550.0 0.14 114400.0 4650.0 0.43 0.4054 0.8934 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P12 mock treatment 121600.0 10300.0 0.95 117600.0 7850.0 0.73 1.1875 0.9912 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P13 compound treatment 118000.0 6750.0 0.62 114000.0 4250.0 0.39 0.7174 0.9759 3132541 CMLD2_000302 COC(OC)[C@@H](C)[C@H](OC)[C@@H](C)[C@H](OC)c1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P14 compound treatment 118000.0 6750.0 0.62 106400.0 -3350.0 -0.31 0.2193 0.3159 3011544 CMLD2_000303 CC(C)c1ccc(C)n1C(=O)OC(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P15 compound treatment 113600.0 2350.0 0.22 107600.0 -2150.0 -0.2 0.0118 0.04 3011545 CMLD2_000304 Brc1ccc(cc1)[C@@H]2OC(=O)C[C@@H]2c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P16 compound treatment 111600.0 349.0 0.03 112400.0 2650.0 0.25 0.1963 0.7929 3132542 CMLD2_000305 COC(=O)[C@H]1[C@@H](C(=O)[C@]2(O)c3ccccc3O[C@@]12c4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P17 mock treatment 126400.0 15100.0 1.39 117200.0 7450.0 0.69 1.4735 0.9475 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P18 compound treatment 116400.0 5150.0 0.47 118400.0 8650.0 0.8 0.9017 0.9685 3132543 CMLD2_000306 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P19 compound treatment 102400.0 -8850.0 -0.81 104800.0 -4950.0 -0.46 -0.9002 -0.9632 3011546 CMLD2_000307 C[C@@H]1CCC2N(C[C@H](O)CN(Cc3ccccc3)C2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P20 compound treatment 124000.0 12700.0 1.17 111200.0 1450.0 0.13 0.9241 0.7829 3132544 CMLD2_000308 CCCCc1nc2CCN(CCOc3ccccc3)Cc2c4CO[C@@H](C)Cc14 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P21 compound treatment 123200.0 11900.0 1.1 122000.0 12200.0 1.14 1.58 0.9999 3131978 CMLD2_000309 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P22 compound treatment 121600.0 10300.0 0.95 118000.0 8250.0 0.76 1.2137 0.9941 3011547 CMLD2_000310 COCC#Cc1ccc(cc1)[C@@H]2N[C@@H](CC[C@H]2C)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P23 compound treatment 127200.0 15900.0 1.47 118000.0 8250.0 0.76 1.578 0.9538 3132545 CMLD2_000311 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@@H]4CC[C@H](C)[C@H](N4C3=O)c5cccc(OC)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2109 P24 compound treatment 108000.0 -3250.0 -0.3 113600.0 3850.0 0.36 0.0408 0.0876 3132534 CMLD2_000312 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A01 compound treatment 120400.0 4450.0 0.41 112800.0 -1620.0 -0.15 0.1835 0.4207 3132546 CMLD2_000313 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A02 compound treatment 123600.0 7650.0 0.7 116400.0 1980.0 0.18 0.6276 0.8627 3011548 CMLD2_000314 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A03 compound treatment 122000.0 6050.0 0.56 119200.0 4780.0 0.44 0.7071 0.9936 3130471 CMLD2_000315 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A04 compound treatment 106800.0 -9150.0 -0.84 108000.0 -6420.0 -0.59 -1.0156 -0.9856 3130472 CMLD2_000316 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A05 compound treatment 111200.0 -4750.0 -0.44 117600.0 3180.0 0.29 -0.1002 -0.1903 3011549 CMLD2_000317 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A06 compound treatment 118000.0 2050.0 0.19 115600.0 1180.0 0.11 0.211 0.9664 3011597 CMLD2_000318 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A07 compound treatment 117600.0 1650.0 0.15 112400.0 -2020.0 -0.19 -0.0248 -0.1028 3130473 CMLD2_000319 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A08 compound treatment 107600.0 -8350.0 -0.77 114000.0 -419.0 -0.04 -0.5704 -0.7419 3010878 CMLD2_000320 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A09 compound treatment 117600.0 1650.0 0.15 113600.0 -819.0 -0.08 0.0539 0.3168 3130474 CMLD2_000321 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A10 compound treatment 114400.0 -1550.0 -0.14 112400.0 -2020.0 -0.19 -0.2329 -0.9908 3010879 CMLD2_000322 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A11 compound treatment 121200.0 5250.0 0.48 111200.0 -3220.0 -0.3 0.1307 0.2302 3130475 CMLD2_000323 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A12 compound treatment 110000.0 -5950.0 -0.55 116400.0 1980.0 0.18 -0.257 -0.4453 3130476 CMLD2_000324 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A13 mock treatment 111600.0 -4350.0 -0.4 116400.0 1980.0 0.18 -0.1529 -0.3475 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A14 mock treatment 121600.0 5650.0 0.52 114800.0 381.0 0.04 0.3927 0.7534 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A15 compound treatment 110000.0 -5950.0 -0.55 109600.0 -4820.0 -0.45 -0.7026 -0.9949 3010880 CMLD2_000325 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A16 compound treatment 117600.0 1650.0 0.15 120000.0 5580.0 0.52 0.4733 0.8778 3130477 CMLD2_000326 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A17 compound treatment 3600.0 -112000.0 -10.33 4400.0 -110000.0 -10.2 -14.5182 -1.0 3010881 CMLD2_000327 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A18 compound treatment 125600.0 9650.0 0.89 116000.0 1580.0 0.15 0.7315 0.8128 3130478 CMLD2_000328 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A19 compound treatment 117200.0 1250.0 0.12 114800.0 381.0 0.04 0.1065 0.8832 3130479 CMLD2_000329 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A20 compound treatment 114400.0 -1550.0 -0.14 118800.0 4380.0 0.41 0.1865 0.4335 3010882 CMLD2_000330 C[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H](C)NC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A21 compound treatment 124400.0 8450.0 0.78 122400.0 7980.0 0.74 1.0729 0.9997 3130480 CMLD2_000331 C[C@H]/1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C\C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A22 compound treatment 118000.0 2050.0 0.19 112800.0 -1620.0 -0.15 0.0274 0.1137 3010883 CMLD2_000332 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc3ccccc3)\C=C\[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A23 compound treatment 116000.0 53.3 0.0 115600.0 1180.0 0.11 0.0809 0.7381 3130481 CMLD2_000333 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 A24 compound treatment 116400.0 453.0 0.04 115600.0 1180.0 0.11 0.1069 0.9125 3130482 CMLD2_000334 C[C@@H]1/C=C/CC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2O)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B01 compound treatment 119200.0 3250.0 0.3 119600.0 5180.0 0.48 0.5512 0.9741 3010884 CMLD2_000335 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B02 compound treatment 120400.0 4450.0 0.41 118800.0 4380.0 0.41 0.5768 1.0 3130483 CMLD2_000336 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B03 compound treatment 126800.0 10900.0 1.0 122800.0 8380.0 0.78 1.2552 0.9923 3130484 CMLD2_000337 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B04 compound treatment 123200.0 7250.0 0.67 119200.0 4780.0 0.44 0.7851 0.9802 3010885 CMLD2_000338 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B05 compound treatment 111200.0 -4750.0 -0.44 116800.0 2380.0 0.22 -0.1527 -0.3121 3130485 CMLD2_000339 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B06 compound treatment 123600.0 7650.0 0.7 133600.0 19200.0 1.78 1.755 0.9178 3010886 CMLD2_000340 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B07 compound treatment 130000.0 14100.0 1.29 122000.0 7580.0 0.7 1.4109 0.959 3130486 CMLD2_000341 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B08 compound treatment 119200.0 3250.0 0.3 121600.0 7180.0 0.67 0.6823 0.9349 3130487 CMLD2_000342 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B09 compound treatment 117600.0 1650.0 0.15 124400.0 9980.0 0.93 0.7617 0.8124 3010887 CMLD2_000343 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B10 compound treatment 119200.0 3250.0 0.3 107600.0 -6820.0 -0.63 -0.2353 -0.3365 3130488 CMLD2_000344 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B11 compound treatment 123600.0 7650.0 0.7 116400.0 1980.0 0.18 0.6276 0.8627 3010888 CMLD2_000345 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B12 compound treatment 123200.0 7250.0 0.67 114800.0 381.0 0.04 0.4967 0.7435 3130489 CMLD2_000346 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B13 mock treatment 123200.0 7250.0 0.67 122000.0 7580.0 0.7 0.9686 0.9997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B14 mock treatment 131200.0 15300.0 1.4 118000.0 3580.0 0.33 1.2268 0.8509 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B15 compound treatment 8400.0 -108000.0 -9.89 10000.0 -104000.0 -9.68 -13.8389 -0.9999 3130616 CMLD2_000347 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCc6ccccc6)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B16 compound treatment 114000.0 -1950.0 -0.18 120800.0 6380.0 0.59 0.2916 0.4719 3010889 CMLD2_000348 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B17 compound treatment 95200.0 -20700.0 -1.91 106000.0 -8420.0 -0.78 -1.9012 -0.9221 3130617 CMLD2_000349 CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B18 compound treatment 120000.0 4050.0 0.37 118800.0 4380.0 0.41 0.5508 0.9991 3010924 CMLD2_000350 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B19 compound treatment 124400.0 8450.0 0.78 118400.0 3980.0 0.37 0.8107 0.942 3130618 CMLD2_000351 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B20 compound treatment 132400.0 16500.0 1.51 123600.0 9180.0 0.85 1.6719 0.9629 3130619 CMLD2_000352 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B21 compound treatment 117600.0 1650.0 0.15 115200.0 781.0 0.07 0.1587 0.9424 3010926 CMLD2_000353 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B22 compound treatment 127600.0 11700.0 1.07 128000.0 13600.0 1.26 1.6481 0.9968 3130620 CMLD2_000354 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B23 compound treatment 124800.0 8850.0 0.81 134800.0 20400.0 1.89 1.9117 0.9293 3130621 CMLD2_000355 C[C@@H]/1COC(=O)N[C@@H](C)C(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 B24 compound treatment 125600.0 9650.0 0.89 120000.0 5580.0 0.52 0.9937 0.9669 3010928 CMLD2_000356 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]3O[C@H](COC1=O)[C@@H](O)C=C3)[C@@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C01 compound treatment 118000.0 2050.0 0.19 113600.0 -819.0 -0.08 0.0799 0.3924 3130622 CMLD2_000357 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C02 compound treatment 126000.0 10100.0 0.92 126000.0 11600.0 1.07 1.4129 0.9972 3130623 CMLD2_000358 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C03 compound treatment 124000.0 8050.0 0.74 118000.0 3580.0 0.33 0.7585 0.9344 3010930 CMLD2_000359 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C04 compound treatment 119200.0 3250.0 0.3 122000.0 7580.0 0.7 0.7085 0.9276 3130624 CMLD2_000360 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C05 compound treatment 116000.0 53.3 0.0 112000.0 -2420.0 -0.22 -0.1551 -0.6915 3010931 CMLD2_000361 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C06 compound treatment 114800.0 -1150.0 -0.11 116000.0 1580.0 0.15 0.029 0.1608 3130625 CMLD2_000362 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C07 compound treatment 110800.0 -5150.0 -0.47 112800.0 -1620.0 -0.15 -0.4409 -0.8877 3130626 CMLD2_000363 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C08 compound treatment 116800.0 853.0 0.08 119200.0 4780.0 0.44 0.3689 0.8196 3010932 CMLD2_000364 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C09 compound treatment 130000.0 14100.0 1.29 116000.0 1580.0 0.15 1.0177 0.7823 3130627 CMLD2_000365 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C10 compound treatment 108800.0 -7150.0 -0.66 109200.0 -5220.0 -0.48 -0.8069 -0.9886 3010933 CMLD2_000366 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C11 mock treatment 121200.0 5250.0 0.48 110800.0 -3620.0 -0.34 0.1045 0.1776 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C12 mock treatment 107600.0 -8350.0 -0.77 113600.0 -819.0 -0.08 -0.5966 -0.7733 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C13 compound treatment 113600.0 -2350.0 -0.22 108800.0 -5620.0 -0.52 -0.5209 -0.924 3130628 CMLD2_000367 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C14 compound treatment 113600.0 -2350.0 -0.22 121600.0 7180.0 0.67 0.318 0.4545 3010934 CMLD2_000368 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C15 mock treatment 116800.0 853.0 0.08 91600.0 -22800.0 -2.12 -1.4401 -0.6804 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C16 mock treatment 111600.0 -4350.0 -0.4 110800.0 -3620.0 -0.34 -0.5199 -0.9962 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C17 compound treatment 116800.0 853.0 0.08 110800.0 -3620.0 -0.34 -0.1817 -0.5274 3130629 CMLD2_000369 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C18 compound treatment 124800.0 8850.0 0.81 114400.0 -19.0 0.0 0.5746 0.7056 3130630 CMLD2_000370 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C19 compound treatment 119200.0 3250.0 0.3 118000.0 3580.0 0.33 0.4463 0.9987 3010935 CMLD2_000371 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C20 compound treatment 125200.0 9250.0 0.85 117600.0 3180.0 0.29 0.8103 0.8996 3130631 CMLD2_000372 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C21 compound treatment 126800.0 10900.0 1.0 114800.0 381.0 0.04 0.7309 0.7317 3010936 CMLD2_000373 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C22 compound treatment 116800.0 853.0 0.08 118000.0 3580.0 0.33 0.2902 0.8509 3130632 CMLD2_000374 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C23 compound treatment 124400.0 8450.0 0.78 125200.0 10800.0 1.0 1.2564 0.9923 3130633 CMLD2_000375 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 C24 compound treatment 117200.0 1250.0 0.12 120800.0 6380.0 0.59 0.4997 0.8293 3010937 CMLD2_000376 C[C@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D01 compound treatment 122400.0 6450.0 0.59 112400.0 -2020.0 -0.19 0.2874 0.4618 3130634 CMLD2_000377 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D02 compound treatment 128800.0 12900.0 1.18 130400.0 16000.0 1.48 1.8834 0.9938 3010938 CMLD2_000378 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D03 compound treatment 128000.0 12100.0 1.11 114000.0 -419.0 -0.04 0.7565 0.6819 3130635 CMLD2_000379 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D04 compound treatment 122000.0 6050.0 0.56 124400.0 9980.0 0.93 1.0479 0.9705 3130759 CMLD2_000380 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D05 compound treatment 115600.0 -347.0 -0.03 111600.0 -2820.0 -0.26 -0.2073 -0.7876 3010939 CMLD2_000381 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D06 compound treatment 118800.0 2850.0 0.26 112000.0 -2420.0 -0.22 0.027 0.0783 3130760 CMLD2_000382 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D07 compound treatment 116000.0 53.3 0.0 113600.0 -819.0 -0.08 -0.0502 -0.66 3130761 CMLD2_000383 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D08 compound treatment 123200.0 7250.0 0.67 111200.0 -3220.0 -0.3 0.2608 0.3568 3130762 CMLD2_000384 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D09 compound treatment 114000.0 -1950.0 -0.18 120400.0 5980.0 0.55 0.2654 0.4555 3010981 CMLD2_000385 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D10 compound treatment 116800.0 853.0 0.08 110800.0 -3620.0 -0.34 -0.1817 -0.5274 3130763 CMLD2_000386 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D11 mock treatment 114400.0 -1550.0 -0.14 119200.0 4780.0 0.44 0.2128 0.4571 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D12 mock treatment 118000.0 2050.0 0.19 113200.0 -1220.0 -0.11 0.0537 0.2438 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D13 compound treatment 118800.0 2850.0 0.26 108400.0 -6020.0 -0.56 -0.2089 -0.3388 3130764 CMLD2_000387 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D14 compound treatment 114400.0 -1550.0 -0.14 119600.0 5180.0 0.48 0.239 0.4771 3010983 CMLD2_000388 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D15 mock treatment 117600.0 1650.0 0.15 112800.0 -1620.0 -0.15 0.0014 0.0067 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D16 mock treatment 116800.0 853.0 0.08 114400.0 -19.0 0.0 0.0543 0.691 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D17 compound treatment 122400.0 6450.0 0.59 117200.0 2780.0 0.26 0.602 0.9302 3130765 CMLD2_000389 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D18 compound treatment 112800.0 -3150.0 -0.29 115200.0 781.0 0.07 -0.1535 -0.5144 3010984 CMLD2_000390 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D19 compound treatment 124400.0 8450.0 0.78 115600.0 1180.0 0.11 0.6272 0.7988 3130766 CMLD2_000391 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D20 compound treatment 116000.0 53.3 0.0 116400.0 1980.0 0.18 0.1333 0.7257 3010985 CMLD2_000392 CO[C@@H]1/C=C/CC(=O)N[C@@H](C)C(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D21 compound treatment 118400.0 2450.0 0.23 122000.0 7580.0 0.7 0.6564 0.8895 3130767 CMLD2_000393 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D22 compound treatment 122800.0 6850.0 0.63 127600.0 13200.0 1.22 1.3097 0.9526 3130768 CMLD2_000394 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D23 compound treatment 115200.0 -747.0 -0.07 123600.0 9180.0 0.85 0.5532 0.6479 3130619 CMLD2_000395 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 D24 compound treatment 120400.0 4450.0 0.41 126000.0 11600.0 1.07 1.0487 0.9127 3010986 CMLD2_000396 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E01 mock treatment 116400.0 453.0 0.04 119200.0 4780.0 0.44 0.3428 0.7702 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E02 mock treatment 112000.0 -3950.0 -0.36 119600.0 5180.0 0.48 0.0829 0.1377 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E03 compound treatment 124400.0 8450.0 0.78 122000.0 7580.0 0.7 1.0467 0.9987 3130769 CMLD2_000397 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E04 compound treatment 118800.0 2850.0 0.26 112000.0 -2420.0 -0.22 0.027 0.0783 3130770 CMLD2_000398 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E05 compound treatment 103200.0 -12700.0 -1.17 102800.0 -11600.0 -1.08 -1.5906 -0.9991 3010987 CMLD2_000399 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E06 compound treatment 121200.0 5250.0 0.48 113200.0 -1220.0 -0.11 0.2618 0.5275 3130771 CMLD2_000400 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E07 compound treatment 116800.0 853.0 0.08 110000.0 -4420.0 -0.41 -0.2341 -0.5614 3130772 CMLD2_000401 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E08 compound treatment 110000.0 -5950.0 -0.55 111200.0 -3220.0 -0.3 -0.5978 -0.9594 3010988 CMLD2_000402 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E09 mock treatment 115600.0 -347.0 -0.03 108000.0 -6420.0 -0.59 -0.4433 -0.7439 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E10 mock treatment 114800.0 -1150.0 -0.11 102800.0 -11600.0 -1.08 -0.8361 -0.7727 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E11 compound treatment 108800.0 -7150.0 -0.66 105200.0 -9220.0 -0.85 -1.0691 -0.9916 3130773 CMLD2_000403 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E12 compound treatment 110800.0 -5150.0 -0.47 95200.0 -19200.0 -1.78 -1.5944 -0.865 3010989 CMLD2_000404 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E13 compound treatment 109200.0 -6750.0 -0.62 109600.0 -4820.0 -0.45 -0.7547 -0.987 3130774 CMLD2_000405 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E14 compound treatment 120400.0 4450.0 0.41 117200.0 2780.0 0.26 0.4719 0.9751 3130775 CMLD2_000406 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E15 compound treatment 103600.0 -12300.0 -1.14 94000.0 -20400.0 -1.89 -2.1414 -0.9702 3010990 CMLD2_000407 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCC(C)C)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E16 compound treatment 116800.0 853.0 0.08 102000.0 -12400.0 -1.15 -0.7585 -0.6574 3130776 CMLD2_000408 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E17 mock treatment 111200.0 -4750.0 -0.44 113600.0 -819.0 -0.08 -0.3624 -0.8178 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E18 mock treatment 112400.0 -3550.0 -0.33 111200.0 -3220.0 -0.3 -0.4417 -0.999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E19 compound treatment 116000.0 53.3 0.0 114400.0 -19.0 0.0 0.0022 0.4259 3010991 CMLD2_000409 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E20 compound treatment 122000.0 6050.0 0.56 110800.0 -3620.0 -0.34 0.1565 0.2408 3130777 CMLD2_000410 C[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E21 compound treatment 120800.0 4850.0 0.45 110400.0 -4020.0 -0.37 0.0523 0.0899 3130778 CMLD2_000411 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E22 compound treatment 120800.0 4850.0 0.45 119200.0 4780.0 0.44 0.629 1.0 3010992 CMLD2_000412 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E23 compound treatment 122000.0 6050.0 0.56 118000.0 3580.0 0.33 0.6284 0.9694 3130904 CMLD2_000413 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C)NS(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 E24 compound treatment 115600.0 -347.0 -0.03 117600.0 3180.0 0.29 0.1859 0.627 3130905 CMLD2_000414 CO[C@@H]1COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F01 mock treatment 116000.0 53.3 0.0 115200.0 781.0 0.07 0.0547 0.7533 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F02 mock treatment 113200.0 -2750.0 -0.25 120400.0 5980.0 0.55 0.2134 0.3502 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F03 compound treatment 119200.0 3250.0 0.3 104400.0 -10000.0 -0.93 -0.4451 -0.4562 3010993 CMLD2_000415 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F04 compound treatment 104000.0 -11900.0 -1.1 106800.0 -7620.0 -0.71 -1.2764 -0.9771 3130906 CMLD2_000416 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F05 compound treatment 106000.0 -9950.0 -0.91 112800.0 -1620.0 -0.15 -0.7531 -0.8122 3130907 CMLD2_000417 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F06 compound treatment 119600.0 3650.0 0.34 116400.0 1980.0 0.18 0.3675 0.9596 3011036 CMLD2_000418 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F07 compound treatment 109600.0 -6350.0 -0.58 110000.0 -4420.0 -0.41 -0.7024 -0.985 3130908 CMLD2_000419 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F08 compound treatment 106000.0 -9950.0 -0.91 105200.0 -9220.0 -0.85 -1.2512 -0.9994 3130909 CMLD2_000420 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F09 mock treatment 108400.0 -7550.0 -0.69 105600.0 -8820.0 -0.82 -1.0689 -0.9967 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F10 mock treatment 110800.0 -5150.0 -0.47 114400.0 -19.0 0.0 -0.336 -0.7097 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F11 compound treatment 105200.0 -10700.0 -0.99 99600.0 -14800.0 -1.37 -1.6703 -0.987 3011038 CMLD2_000421 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F12 compound treatment 98400.0 -17500.0 -1.61 91200.0 -23200.0 -2.15 -2.6631 -0.9899 3130910 CMLD2_000422 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F13 compound treatment 101600.0 -14300.0 -1.32 93600.0 -20800.0 -1.93 -2.2977 -0.9828 3011039 CMLD2_000423 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F14 compound treatment 105200.0 -10700.0 -0.99 100000.0 -14400.0 -1.34 -1.644 -0.989 3130911 CMLD2_000424 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F15 compound treatment 89200.0 -26700.0 -2.46 80000.0 -34400.0 -3.19 -3.9956 -0.9918 3130912 CMLD2_000425 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC\C=C(/C)\CCC=C(C)C)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F16 compound treatment 103200.0 -12700.0 -1.17 107200.0 -7220.0 -0.67 -1.3022 -0.9646 3011040 CMLD2_000426 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F17 mock treatment 109200.0 -6750.0 -0.62 109200.0 -5220.0 -0.48 -0.7809 -0.9924 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F18 mock treatment 106400.0 -9550.0 -0.88 105200.0 -9220.0 -0.85 -1.2252 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F19 compound treatment 108400.0 -7550.0 -0.69 109200.0 -5220.0 -0.48 -0.8329 -0.9844 3011041 CMLD2_000427 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F20 compound treatment 113200.0 -2750.0 -0.25 111200.0 -3220.0 -0.3 -0.3896 -0.9966 3130913 CMLD2_000428 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F21 compound treatment 116400.0 453.0 0.04 110400.0 -4020.0 -0.37 -0.2339 -0.6241 3130914 CMLD2_000429 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F22 compound treatment 124800.0 8850.0 0.81 124400.0 9980.0 0.93 1.23 0.998 3011043 CMLD2_000430 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC1=O)[C@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F23 compound treatment 118400.0 2450.0 0.23 114400.0 -19.0 0.0 0.1583 0.7016 3130915 CMLD2_000431 CO[C@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 F24 compound treatment 112000.0 -3950.0 -0.36 114800.0 381.0 0.04 -0.2317 -0.6353 3011044 CMLD2_000432 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G01 compound treatment 116800.0 853.0 0.08 123200.0 8780.0 0.81 0.631 0.7717 3130916 CMLD2_000433 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G02 compound treatment 116000.0 53.3 0.0 117600.0 3180.0 0.29 0.212 0.7188 3130917 CMLD2_000434 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G03 mock treatment 115200.0 -747.0 -0.07 115600.0 1180.0 0.11 0.0288 0.2232 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G04 mock treatment 116000.0 53.3 0.0 117200.0 2780.0 0.26 0.1857 0.7204 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G05 compound treatment 117600.0 1650.0 0.15 119200.0 4780.0 0.44 0.4209 0.8983 3011046 CMLD2_000435 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G06 compound treatment 116000.0 53.3 0.0 111200.0 -3220.0 -0.3 -0.2075 -0.6954 3130918 CMLD2_000436 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G07 compound treatment 112800.0 -3150.0 -0.29 114400.0 -19.0 0.0 -0.2059 -0.7114 3130919 CMLD2_000437 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G08 compound treatment 113200.0 -2750.0 -0.25 106400.0 -8020.0 -0.74 -0.7042 -0.8971 3011047 CMLD2_000438 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G09 compound treatment 109600.0 -6350.0 -0.58 97600.0 -16800.0 -1.56 -1.5152 -0.9102 3130920 CMLD2_000439 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G10 compound treatment 108800.0 -7150.0 -0.66 101600.0 -12800.0 -1.19 -1.305 -0.961 3011048 CMLD2_000440 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G11 compound treatment 108000.0 -7950.0 -0.73 104000.0 -10400.0 -0.97 -1.1998 -0.9906 3130921 CMLD2_000441 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G12 compound treatment 108000.0 -7950.0 -0.73 98400.0 -16000.0 -1.48 -1.5668 -0.9467 3131048 CMLD2_000442 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G13 compound treatment 101200.0 -14700.0 -1.36 108400.0 -6020.0 -0.56 -1.3537 -0.9229 3011049 CMLD2_000443 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G14 compound treatment 109600.0 -6350.0 -0.58 102800.0 -11600.0 -1.08 -1.1743 -0.9586 3131049 CMLD2_000444 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(CC)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G15 compound treatment 55200.0 -60700.0 -5.59 40800.0 -73600.0 -6.82 -8.7763 -0.9951 3011050 CMLD2_000445 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCCCC#C)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G16 compound treatment 4800.0 -111000.0 -10.22 5200.0 -109000.0 -10.12 -14.3877 -1.0 3131050 CMLD2_000446 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G17 compound treatment 110800.0 -5150.0 -0.47 113200.0 -1220.0 -0.11 -0.4147 -0.8519 3131051 CMLD2_000447 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G18 compound treatment 108400.0 -7550.0 -0.69 112400.0 -2020.0 -0.19 -0.6232 -0.8668 3011052 CMLD2_000448 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G19 mock treatment 114000.0 -1950.0 -0.18 112000.0 -2420.0 -0.22 -0.2852 -0.9938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G20 mock treatment 119600.0 3650.0 0.34 113200.0 -1220.0 -0.11 0.1577 0.4449 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G21 compound treatment 112800.0 -3150.0 -0.29 112800.0 -1620.0 -0.15 -0.3108 -0.9532 3131052 CMLD2_000449 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C\C=C\[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G22 compound treatment 114800.0 -1150.0 -0.11 109200.0 -5220.0 -0.48 -0.4166 -0.8415 3011053 CMLD2_000450 C[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G23 compound treatment 126000.0 10100.0 0.92 120000.0 5580.0 0.52 1.0197 0.9623 3131053 CMLD2_000451 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@@H]3CCCN3C1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 G24 compound treatment 120400.0 4450.0 0.41 119600.0 5180.0 0.48 0.6292 0.9969 3131054 CMLD2_000452 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H01 compound treatment 121600.0 5650.0 0.52 115600.0 1180.0 0.11 0.4451 0.8376 3011098 CMLD2_000453 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H02 compound treatment 114800.0 -1150.0 -0.11 124400.0 9980.0 0.93 0.5796 0.6225 3131055 CMLD2_000454 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H03 mock treatment 116400.0 453.0 0.04 113600.0 -819.0 -0.08 -0.0242 -0.2793 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H04 mock treatment 116000.0 53.3 0.0 115600.0 1180.0 0.11 0.0809 0.7381 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H05 compound treatment 108800.0 -7150.0 -0.66 114400.0 -19.0 0.0 -0.4661 -0.709 3131056 CMLD2_000455 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H06 compound treatment 121600.0 5650.0 0.52 114000.0 -419.0 -0.04 0.3402 0.6525 3011099 CMLD2_000456 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H07 compound treatment 120400.0 4450.0 0.41 113200.0 -1220.0 -0.11 0.2098 0.4936 3131057 CMLD2_000457 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H08 compound treatment 110000.0 -5950.0 -0.55 110400.0 -4020.0 -0.37 -0.6502 -0.9825 3011100 CMLD2_000458 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H09 compound treatment 102800.0 -13100.0 -1.21 108400.0 -6020.0 -0.56 -1.2496 -0.9383 3131058 CMLD2_000459 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H10 compound treatment 104400.0 -11500.0 -1.06 102400.0 -12000.0 -1.11 -1.5388 -0.9997 3131059 CMLD2_000460 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H11 compound treatment 111200.0 -4750.0 -0.44 102000.0 -12400.0 -1.15 -1.1227 -0.9119 3011101 CMLD2_000461 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H12 compound treatment 107600.0 -8350.0 -0.77 112000.0 -2420.0 -0.22 -0.7014 -0.877 3131060 CMLD2_000462 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H13 compound treatment 108000.0 -7950.0 -0.73 94000.0 -20400.0 -1.89 -1.8552 -0.9144 3131061 CMLD2_000463 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H14 compound treatment 109600.0 -6350.0 -0.58 106400.0 -8020.0 -0.74 -0.9384 -0.9929 3011102 CMLD2_000464 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H15 compound treatment 85600.0 -30300.0 -2.79 90400.0 -24000.0 -2.23 -3.5481 -0.9937 3131062 CMLD2_000465 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC[C@@H](O)COCc6ccco6)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H16 compound treatment 108000.0 -7950.0 -0.73 99200.0 -15200.0 -1.41 -1.5144 -0.9531 3011103 CMLD2_000466 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H17 compound treatment 110000.0 -5950.0 -0.55 105600.0 -8820.0 -0.82 -0.9648 -0.9809 3131063 CMLD2_000467 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H18 compound treatment 122800.0 6850.0 0.63 112400.0 -2020.0 -0.19 0.3134 0.4766 3011104 CMLD2_000468 CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H19 mock treatment 116400.0 453.0 0.04 109200.0 -5220.0 -0.48 -0.3126 -0.6438 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H20 mock treatment 113600.0 -2350.0 -0.22 115200.0 781.0 0.07 -0.1014 -0.4456 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H21 compound treatment 120800.0 4850.0 0.45 112800.0 -1620.0 -0.15 0.2096 0.4449 3131064 CMLD2_000469 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H22 compound treatment 117200.0 1250.0 0.12 116800.0 2380.0 0.22 0.2376 0.9541 3011105 CMLD2_000470 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H23 compound treatment 123200.0 7250.0 0.67 122800.0 8380.0 0.78 1.0211 0.9971 3131065 CMLD2_000471 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 H24 compound treatment 123600.0 7650.0 0.7 131600.0 17200.0 1.59 1.6239 0.9326 3131066 CMLD2_000472 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I01 compound treatment 126000.0 10100.0 0.92 124000.0 9580.0 0.89 1.2818 0.9998 3011106 CMLD2_000473 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I02 compound treatment 127600.0 11700.0 1.07 118800.0 4380.0 0.41 1.0451 0.9117 3131067 CMLD2_000474 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I03 compound treatment 124400.0 8450.0 0.78 122400.0 7980.0 0.74 1.0729 0.9997 3131183 CMLD2_000475 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I04 compound treatment 118000.0 2050.0 0.19 112400.0 -2020.0 -0.19 0.0012 0.0046 3011108 CMLD2_000476 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I05 mock treatment 120000.0 4050.0 0.37 109600.0 -4820.0 -0.45 -0.0522 -0.0897 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I06 mock treatment 118800.0 2850.0 0.26 123200.0 8780.0 0.81 0.7611 0.89 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I07 compound treatment 118400.0 2450.0 0.23 112800.0 -1620.0 -0.15 0.0535 0.1972 3131184 CMLD2_000477 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I08 compound treatment 111600.0 -4350.0 -0.4 116000.0 1580.0 0.15 -0.1791 -0.4206 3011109 CMLD2_000478 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I09 compound treatment 114800.0 -1150.0 -0.11 114000.0 -419.0 -0.04 -0.102 -0.9079 3131185 CMLD2_000479 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I10 compound treatment 111200.0 -4750.0 -0.44 110800.0 -3620.0 -0.34 -0.5459 -0.9915 3131186 CMLD2_000480 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I11 compound treatment 114000.0 -1950.0 -0.18 104800.0 -9620.0 -0.89 -0.7571 -0.8325 3011110 CMLD2_000481 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I12 compound treatment 114800.0 -1150.0 -0.11 112800.0 -1620.0 -0.15 -0.1807 -0.9851 3131187 CMLD2_000482 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I13 compound treatment 96000.0 -19900.0 -1.83 93600.0 -20800.0 -1.93 -2.6619 -0.9997 3131188 CMLD2_000483 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I14 compound treatment 108400.0 -7550.0 -0.69 103600.0 -10800.0 -1.0 -1.2 -0.9839 3011112 CMLD2_000484 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I15 compound treatment 96800.0 -19100.0 -1.76 102000.0 -12400.0 -1.15 -2.0593 -0.9788 3131189 CMLD2_000485 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCc5ccccc5)n2c1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I16 compound treatment 48400.0 -67500.0 -6.21 34000.0 -80400.0 -7.45 -9.6642 -0.9959 3011154 CMLD2_000486 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I17 compound treatment 112400.0 -3550.0 -0.33 105200.0 -9220.0 -0.85 -0.8349 -0.9128 3131190 CMLD2_000487 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I18 compound treatment 116000.0 53.3 0.0 100000.0 -14400.0 -1.34 -0.9416 -0.7045 3010995 CMLD2_000488 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I19 compound treatment 108000.0 -7950.0 -0.73 108800.0 -5620.0 -0.52 -0.8852 -0.9862 3131191 CMLD2_000489 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I20 compound treatment 121200.0 5250.0 0.48 117600.0 3180.0 0.29 0.5502 0.9719 3131192 CMLD2_000490 C[C@H]/1COC(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I21 mock treatment 118800.0 2850.0 0.26 112800.0 -1620.0 -0.15 0.0795 0.2629 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I22 mock treatment 132000.0 16100.0 1.48 125200.0 10800.0 1.0 1.7508 0.9819 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I23 compound treatment 116800.0 853.0 0.08 119600.0 5180.0 0.48 0.3951 0.8119 3131193 CMLD2_000491 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 I24 compound treatment 123600.0 7650.0 0.7 124000.0 9580.0 0.89 1.1257 0.9934 3011157 CMLD2_000492 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J01 compound treatment 125600.0 9650.0 0.89 119600.0 5180.0 0.48 0.9674 0.9583 3131194 CMLD2_000493 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J02 compound treatment 126800.0 10900.0 1.0 120800.0 6380.0 0.59 1.1241 0.9688 3011158 CMLD2_000494 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J03 compound treatment 120800.0 4850.0 0.45 118400.0 3980.0 0.37 0.5766 0.9955 3131195 CMLD2_000495 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J04 compound treatment 122400.0 6450.0 0.59 120400.0 5980.0 0.55 0.8117 0.9994 3011159 CMLD2_000496 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J05 mock treatment 114000.0 -1950.0 -0.18 125200.0 10800.0 1.0 0.58 0.5713 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J06 mock treatment 114800.0 -1150.0 -0.11 119600.0 5180.0 0.48 0.265 0.539 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J07 compound treatment 112000.0 -3950.0 -0.36 104800.0 -9620.0 -0.89 -0.8872 -0.9216 3131196 CMLD2_000497 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J08 compound treatment 111600.0 -4350.0 -0.4 112000.0 -2420.0 -0.22 -0.4413 -0.9626 3131197 CMLD2_000498 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J09 compound treatment 117200.0 1250.0 0.12 108400.0 -6020.0 -0.56 -0.313 -0.5494 3011160 CMLD2_000499 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J10 compound treatment 118800.0 2850.0 0.26 108800.0 -5620.0 -0.52 -0.1827 -0.3133 3131198 CMLD2_000500 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J11 compound treatment 106000.0 -9950.0 -0.91 101600.0 -12800.0 -1.19 -1.4871 -0.9917 3011161 CMLD2_000501 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J12 compound treatment 108400.0 -7550.0 -0.69 114000.0 -419.0 -0.04 -0.5183 -0.7455 3131199 CMLD2_000502 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J13 compound treatment 115600.0 -347.0 -0.03 112400.0 -2020.0 -0.19 -0.1549 -0.8158 3131200 CMLD2_000503 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J14 compound treatment 100800.0 -15100.0 -1.39 94000.0 -20400.0 -1.89 -2.3235 -0.9886 3011162 CMLD2_000504 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J15 compound treatment 113200.0 -2750.0 -0.25 108800.0 -5620.0 -0.52 -0.5469 -0.9448 3131201 CMLD2_000505 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J16 compound treatment 110400.0 -5550.0 -0.51 115200.0 781.0 0.07 -0.3096 -0.6008 3011163 CMLD2_000506 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J17 compound treatment 112800.0 -3150.0 -0.29 107600.0 -6820.0 -0.63 -0.6516 -0.9373 3131202 CMLD2_000507 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J18 compound treatment 112800.0 -3150.0 -0.29 116000.0 1580.0 0.15 -0.101 -0.3115 3011164 CMLD2_000508 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J19 compound treatment 119600.0 3650.0 0.34 114000.0 -419.0 -0.04 0.2102 0.6212 3131320 CMLD2_000509 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J20 compound treatment 132800.0 16900.0 1.55 127600.0 13200.0 1.22 1.9601 0.9931 3131321 CMLD2_000510 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J21 mock treatment 113200.0 -2750.0 -0.25 115600.0 1180.0 0.11 -0.1012 -0.3677 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J22 mock treatment 119200.0 3250.0 0.3 109200.0 -5220.0 -0.48 -0.1305 -0.2293 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J23 compound treatment 128400.0 12500.0 1.15 119200.0 4780.0 0.44 1.1233 0.9146 1952481 CMLD2_000511 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 J24 compound treatment 123200.0 7250.0 0.67 118400.0 3980.0 0.37 0.7327 0.961 3131322 CMLD2_000512 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K01 compound treatment 116400.0 453.0 0.04 122000.0 7580.0 0.7 0.5264 0.7478 3131323 CMLD2_000513 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K02 compound treatment 119200.0 3250.0 0.3 112800.0 -1620.0 -0.15 0.1055 0.3151 3011055 CMLD2_000514 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K03 compound treatment 116000.0 53.3 0.0 108000.0 -6420.0 -0.59 -0.4172 -0.7013 3131324 CMLD2_000515 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K04 compound treatment 115600.0 -347.0 -0.03 120400.0 5980.0 0.55 0.3695 0.6653 3011057 CMLD2_000516 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K05 compound treatment 111600.0 -4350.0 -0.4 114800.0 381.0 0.04 -0.2577 -0.6422 3131325 CMLD2_000517 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K06 compound treatment 116000.0 53.3 0.0 106800.0 -7620.0 -0.71 -0.4959 -0.7022 3131326 CMLD2_000518 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K07 mock treatment 115200.0 -747.0 -0.07 105200.0 -9220.0 -0.85 -0.6528 -0.7615 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K08 mock treatment 114400.0 -1550.0 -0.14 117600.0 3180.0 0.29 0.1079 0.3296 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K09 compound treatment 107200.0 -8750.0 -0.8 108400.0 -6020.0 -0.56 -0.9634 -0.984 3011058 CMLD2_000519 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K10 compound treatment 113200.0 -2750.0 -0.25 105200.0 -9220.0 -0.85 -0.7829 -0.8786 3131327 CMLD2_000520 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K11 compound treatment 103200.0 -12700.0 -1.17 102800.0 -11600.0 -1.08 -1.5906 -0.9991 3011059 CMLD2_000521 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K12 compound treatment 124000.0 8050.0 0.74 107200.0 -7220.0 -0.67 0.0507 0.0507 3131328 CMLD2_000522 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K13 compound treatment 104000.0 -11900.0 -1.1 98000.0 -16400.0 -1.52 -1.8532 -0.9872 3131329 CMLD2_000523 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K14 compound treatment 92400.0 -23500.0 -2.17 83200.0 -31200.0 -2.89 -3.5777 -0.9898 3011060 CMLD2_000524 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(c6ccccc6)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K15 mock treatment 112800.0 -3150.0 -0.29 116800.0 2380.0 0.22 -0.0486 -0.1336 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K16 mock treatment 111200.0 -4750.0 -0.44 105200.0 -9220.0 -0.85 -0.913 -0.9514 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K17 compound treatment 102800.0 -13100.0 -1.21 105200.0 -9220.0 -0.85 -1.4593 -0.9855 3131330 CMLD2_000525 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K18 compound treatment 117600.0 1650.0 0.15 98000.0 -16400.0 -1.52 -0.9686 -0.6333 3011061 CMLD2_000526 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K19 compound treatment 115600.0 -347.0 -0.03 109200.0 -5220.0 -0.48 -0.3646 -0.7521 3131331 CMLD2_000527 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K20 compound treatment 121200.0 5250.0 0.48 120400.0 5980.0 0.55 0.7337 0.9977 3011062 CMLD2_000528 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K21 compound treatment 126800.0 10900.0 1.0 117600.0 3180.0 0.29 0.9144 0.8784 3011070 CMLD2_000529 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K22 compound treatment 125200.0 9250.0 0.85 119200.0 4780.0 0.44 0.9152 0.9537 3011072 CMLD2_000530 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)COC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K23 mock treatment 128400.0 12500.0 1.15 118800.0 4380.0 0.41 1.0971 0.9027 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 K24 mock treatment 121200.0 5250.0 0.48 123600.0 9180.0 0.85 0.9434 0.964 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L01 compound treatment 121600.0 5650.0 0.52 120000.0 5580.0 0.52 0.7335 1.0 3131332 CMLD2_000531 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L02 compound treatment 130800.0 14900.0 1.37 124800.0 10400.0 0.96 1.6465 0.9853 3131333 CMLD2_000532 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L03 compound treatment 120400.0 4450.0 0.41 120000.0 5580.0 0.52 0.6554 0.9933 3011074 CMLD2_000533 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L04 compound treatment 120400.0 4450.0 0.41 124400.0 9980.0 0.93 0.9438 0.9328 3131334 CMLD2_000534 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L05 compound treatment 124000.0 8050.0 0.74 117600.0 3180.0 0.29 0.7323 0.9185 3131335 CMLD2_000535 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L06 compound treatment 112000.0 -3950.0 -0.36 116000.0 1580.0 0.15 -0.1531 -0.391 3011078 CMLD2_000536 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L07 mock treatment 119200.0 3250.0 0.3 111600.0 -2820.0 -0.26 0.0268 0.0676 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L08 mock treatment 116000.0 53.3 0.0 114000.0 -419.0 -0.04 -0.024 -0.6129 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L09 compound treatment 122800.0 6850.0 0.63 120400.0 5980.0 0.55 0.8378 0.9979 3011128 CMLD2_000537 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L10 compound treatment 117200.0 1250.0 0.12 107600.0 -6820.0 -0.63 -0.3654 -0.5687 3131336 CMLD2_000538 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L11 compound treatment 113600.0 -2350.0 -0.22 103200.0 -11200.0 -1.04 -0.888 -0.8361 3011131 CMLD2_000539 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L12 compound treatment 112400.0 -3550.0 -0.33 106400.0 -8020.0 -0.74 -0.7563 -0.9317 3131337 CMLD2_000540 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L13 compound treatment 115600.0 -347.0 -0.03 105600.0 -8820.0 -0.82 -0.6006 -0.7341 3131338 CMLD2_000541 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L14 compound treatment 93600.0 -22300.0 -2.06 82000.0 -32400.0 -3.0 -3.5783 -0.9829 3011134 CMLD2_000542 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L15 mock treatment 118000.0 2050.0 0.19 107600.0 -6820.0 -0.63 -0.3134 -0.4751 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L16 mock treatment 114800.0 -1150.0 -0.11 108800.0 -5620.0 -0.52 -0.4429 -0.8334 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L17 compound treatment 114400.0 -1550.0 -0.14 114800.0 381.0 0.04 -0.0756 -0.516 3131454 CMLD2_000543 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L18 compound treatment 108800.0 -7150.0 -0.66 100400.0 -14000.0 -1.3 -1.3837 -0.9502 3011136 CMLD2_000544 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]4[C@H]([C@H](O)[C@@H]5O[C@@H]5C4=O)n3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L19 compound treatment 118800.0 2850.0 0.26 114400.0 -19.0 0.0 0.1843 0.7023 3131455 CMLD2_000545 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L20 compound treatment 110000.0 -5950.0 -0.55 118000.0 3580.0 0.33 -0.1521 -0.2377 3131456 CMLD2_000546 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2)NS(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L21 compound treatment 118800.0 2850.0 0.26 115600.0 1180.0 0.11 0.263 0.9248 3011138 CMLD2_000547 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L22 compound treatment 129600.0 13700.0 1.26 114000.0 -419.0 -0.04 0.8606 0.6849 3131457 CMLD2_000548 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L23 mock treatment 131200.0 15300.0 1.4 123200.0 8780.0 0.81 1.5676 0.9665 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 L24 mock treatment 122800.0 6850.0 0.63 125200.0 10800.0 1.0 1.1524 0.9753 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M01 compound treatment 124000.0 8050.0 0.74 117600.0 3180.0 0.29 0.7323 0.9185 3011140 CMLD2_000549 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M02 compound treatment 124400.0 8450.0 0.78 116400.0 1980.0 0.18 0.6797 0.8507 3131458 CMLD2_000550 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M03 compound treatment 114800.0 -1150.0 -0.11 116400.0 1980.0 0.18 0.0553 0.2609 3131459 CMLD2_000551 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M04 compound treatment 120400.0 4450.0 0.41 115200.0 781.0 0.07 0.3408 0.8194 3011143 CMLD2_000552 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M05 compound treatment 114400.0 -1550.0 -0.14 117600.0 3180.0 0.29 0.1079 0.3296 3011168 CMLD2_000553 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M06 compound treatment 110400.0 -5550.0 -0.51 120400.0 5980.0 0.55 0.0312 0.0415 3131460 CMLD2_000554 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M07 compound treatment 111600.0 -4350.0 -0.4 113200.0 -1220.0 -0.11 -0.3626 -0.8728 3011171 CMLD2_000555 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M08 compound treatment 122400.0 6450.0 0.59 109600.0 -4820.0 -0.45 0.1039 0.1398 3131461 CMLD2_000556 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M09 mock treatment 114400.0 -1550.0 -0.14 112000.0 -2420.0 -0.22 -0.2591 -0.9759 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M10 mock treatment 117200.0 1250.0 0.12 109600.0 -4820.0 -0.45 -0.2343 -0.508 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M11 compound treatment 98000.0 -17900.0 -1.65 90400.0 -24000.0 -2.23 -2.7416 -0.9892 3011173 CMLD2_000557 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M12 compound treatment 111200.0 -4750.0 -0.44 111600.0 -2820.0 -0.26 -0.4935 -0.9699 3131462 CMLD2_000558 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(CC)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M13 mock treatment 112800.0 -3150.0 -0.29 111200.0 -3220.0 -0.3 -0.4157 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M14 mock treatment 113600.0 -2350.0 -0.22 108000.0 -6420.0 -0.59 -0.5734 -0.9059 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M15 compound treatment 104800.0 -11100.0 -1.03 107600.0 -6820.0 -0.63 -1.1719 -0.973 3131463 CMLD2_000559 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M16 compound treatment 78000.0 -37900.0 -3.49 97600.0 -16800.0 -1.56 -3.5705 -0.934 3011176 CMLD2_000560 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M17 compound treatment 116000.0 53.3 0.0 117600.0 3180.0 0.29 0.212 0.7188 3131464 CMLD2_000561 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M18 compound treatment 114800.0 -1150.0 -0.11 105200.0 -9220.0 -0.85 -0.6788 -0.7884 3011178 CMLD2_000562 Cn1c(=O)n2CC[C@H]3[C@H]([C@H](O)[C@@H]4O[C@@H]4C3=O)n2c1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M19 compound treatment 118800.0 2850.0 0.26 114800.0 381.0 0.04 0.2106 0.7951 3131465 CMLD2_000563 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M20 compound treatment 119600.0 3650.0 0.34 112800.0 -1620.0 -0.15 0.1315 0.3573 3011181 CMLD2_000564 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M21 compound treatment 117600.0 1650.0 0.15 113200.0 -1220.0 -0.11 0.0276 0.1459 3131466 CMLD2_000565 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M22 compound treatment 122000.0 6050.0 0.56 122400.0 7980.0 0.74 0.9168 0.9902 3011183 CMLD2_000566 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M23 compound treatment 127200.0 11300.0 1.04 121600.0 7180.0 0.67 1.2026 0.9772 3131467 CMLD2_000567 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 M24 compound treatment 119600.0 3650.0 0.34 129200.0 14800.0 1.37 1.2064 0.8552 3131468 CMLD2_000568 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N01 compound treatment 112000.0 -3950.0 -0.36 114400.0 -19.0 0.0 -0.2579 -0.7105 3131469 CMLD2_000569 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N02 compound treatment 132800.0 16900.0 1.55 118800.0 4380.0 0.41 1.3833 0.8632 3011201 CMLD2_000570 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N03 compound treatment 126800.0 10900.0 1.0 116800.0 2380.0 0.22 0.862 0.8431 3131470 CMLD2_000571 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N04 compound treatment 116400.0 453.0 0.04 127600.0 13200.0 1.22 0.8934 0.7308 3131471 CMLD2_000572 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N05 compound treatment 128400.0 12500.0 1.15 113600.0 -819.0 -0.08 0.7563 0.6588 3011203 CMLD2_000573 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N06 compound treatment 124800.0 8850.0 0.81 112800.0 -1620.0 -0.15 0.4697 0.5673 3131472 CMLD2_000574 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N07 compound treatment 124800.0 8850.0 0.81 118000.0 3580.0 0.33 0.8105 0.9217 3011205 CMLD2_000575 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N08 compound treatment 122400.0 6450.0 0.59 118800.0 4380.0 0.41 0.7069 0.9829 3131588 CMLD2_000576 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N09 mock treatment 128000.0 12100.0 1.11 120800.0 6380.0 0.59 1.2022 0.9567 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N10 mock treatment 117600.0 1650.0 0.15 119600.0 5180.0 0.48 0.4471 0.8876 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N11 compound treatment 117600.0 1650.0 0.15 107200.0 -7220.0 -0.67 -0.3656 -0.5328 3011207 CMLD2_000577 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N12 compound treatment 109200.0 -6750.0 -0.62 109200.0 -5220.0 -0.48 -0.7809 -0.9924 3131589 CMLD2_000578 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N13 mock treatment 113600.0 -2350.0 -0.22 114000.0 -419.0 -0.04 -0.1801 -0.8212 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N14 mock treatment 116000.0 53.3 0.0 106800.0 -7620.0 -0.71 -0.4959 -0.7022 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N15 compound treatment 118000.0 2050.0 0.19 114800.0 381.0 0.04 0.1585 0.825 3131590 CMLD2_000579 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCCCC#C)n2c1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N16 compound treatment 4000.0 -112000.0 -10.3 3600.0 -111000.0 -10.27 -14.5446 -1.0 3011210 CMLD2_000580 C[C@@H](N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N17 compound treatment 112400.0 -3550.0 -0.33 115600.0 1180.0 0.11 -0.1533 -0.4454 3131591 CMLD2_000581 C[C@H](N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N18 compound treatment 122000.0 6050.0 0.56 112800.0 -1620.0 -0.15 0.2876 0.4987 3011211 CMLD2_000582 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N19 compound treatment 114400.0 -1550.0 -0.14 122400.0 7980.0 0.74 0.4225 0.5608 3131592 CMLD2_000583 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N20 compound treatment 115200.0 -747.0 -0.07 122800.0 8380.0 0.78 0.5007 0.6421 3131593 CMLD2_000584 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N21 compound treatment 120800.0 4850.0 0.45 119600.0 5180.0 0.48 0.6552 0.9993 3011214 CMLD2_000585 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@H](C)C(=O)OC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N22 compound treatment 119200.0 3250.0 0.3 123200.0 8780.0 0.81 0.7871 0.9077 3011226 CMLD2_000586 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N23 compound treatment 127600.0 11700.0 1.07 121600.0 7180.0 0.67 1.2286 0.9737 3131594 CMLD2_000587 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]3CCCN3C(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 N24 compound treatment 119200.0 3250.0 0.3 125200.0 10800.0 1.0 0.9182 0.8802 3131054 CMLD2_000588 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O01 compound treatment 124400.0 8450.0 0.78 128400.0 14000.0 1.3 1.4662 0.9701 3131595 CMLD2_000589 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O02 compound treatment 130400.0 14500.0 1.33 128800.0 14400.0 1.33 1.8826 1.0 3011229 CMLD2_000590 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O03 compound treatment 126400.0 10500.0 0.96 110800.0 -3620.0 -0.34 0.4427 0.4347 3131596 CMLD2_000591 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O04 compound treatment 119200.0 3250.0 0.3 126400.0 12000.0 1.11 0.9969 0.8667 3011196 CMLD2_000592 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O05 compound treatment 125600.0 9650.0 0.89 122400.0 7980.0 0.74 1.151 0.9959 3131597 CMLD2_000593 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O06 compound treatment 124000.0 8050.0 0.74 118400.0 3980.0 0.37 0.7847 0.9482 3131598 CMLD2_000594 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O07 compound treatment 124400.0 8450.0 0.78 128000.0 13600.0 1.26 1.4399 0.9732 3011231 CMLD2_000595 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O08 compound treatment 124000.0 8050.0 0.74 122800.0 8380.0 0.78 1.0731 0.9997 3131599 CMLD2_000596 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O09 compound treatment 115600.0 -347.0 -0.03 121200.0 6780.0 0.63 0.4219 0.6704 3011237 CMLD2_000597 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O10 compound treatment 116800.0 853.0 0.08 110400.0 -4020.0 -0.37 -0.2079 -0.5461 3131600 CMLD2_000598 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O11 mock treatment 118000.0 2050.0 0.19 116800.0 2380.0 0.22 0.2896 0.997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O12 mock treatment 136000.0 20100.0 1.84 115200.0 781.0 0.07 1.3555 0.7343 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O13 compound treatment 120000.0 4050.0 0.37 116000.0 1580.0 0.15 0.3673 0.9168 3011239 CMLD2_000599 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O14 compound treatment 87200.0 -28700.0 -2.64 76800.0 -37600.0 -3.49 -4.3354 -0.9907 3131601 CMLD2_000600 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)/C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O15 compound treatment 112800.0 -3150.0 -0.29 112000.0 -2420.0 -0.22 -0.3632 -0.992 3131602 CMLD2_000601 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OC[C@@H](O)COCc5ccco5)n2c1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O16 compound treatment 74000.0 -41900.0 -3.86 62800.0 -51600.0 -4.78 -6.1115 -0.9943 3012175 CMLD2_000602 CCOC(=O)CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O17 compound treatment 127600.0 11700.0 1.07 116800.0 2380.0 0.22 0.914 0.8352 3012176 CMLD2_000603 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O18 compound treatment 122000.0 6050.0 0.56 112400.0 -2020.0 -0.19 0.2614 0.445 3012177 CMLD2_000604 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccccc4)C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O19 compound treatment 122800.0 6850.0 0.63 116000.0 1580.0 0.15 0.5494 0.8488 3012178 CMLD2_000605 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O20 compound treatment 127200.0 11300.0 1.04 132400.0 18000.0 1.67 1.9105 0.9738 3012179 CMLD2_000606 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O21 compound treatment 134400.0 18500.0 1.7 120000.0 5580.0 0.52 1.566 0.8825 3131603 CMLD2_000607 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@@H](C)C(=O)OC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O22 compound treatment 133600.0 17700.0 1.62 126000.0 11600.0 1.07 1.9073 0.9798 3011105 CMLD2_000608 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O23 compound treatment 121600.0 5650.0 0.52 128400.0 14000.0 1.3 1.284 0.9196 3012180 CMLD2_000609 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 O24 compound treatment 125200.0 9250.0 0.85 124000.0 9580.0 0.89 1.2298 0.9998 3131604 CMLD2_000610 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P01 compound treatment 116400.0 453.0 0.04 117200.0 2780.0 0.26 0.2118 0.811 3131605 CMLD2_000611 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P02 compound treatment 132000.0 16100.0 1.48 124000.0 9580.0 0.89 1.6721 0.9704 3012181 CMLD2_000612 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P03 compound treatment 128400.0 12500.0 1.15 130800.0 16400.0 1.52 1.8836 0.9903 3131606 CMLD2_000613 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P04 compound treatment 130800.0 14900.0 1.37 115600.0 1180.0 0.11 1.0435 0.7613 3012182 CMLD2_000614 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P05 compound treatment 121600.0 5650.0 0.52 115600.0 1180.0 0.11 0.4451 0.8376 3131723 CMLD2_000615 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P06 compound treatment 126400.0 10500.0 0.96 122800.0 8380.0 0.78 1.2292 0.9944 3131724 CMLD2_000616 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P07 compound treatment 128800.0 12900.0 1.18 120400.0 5980.0 0.55 1.228 0.9404 3012183 CMLD2_000617 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P08 compound treatment 118400.0 2450.0 0.23 104000.0 -10400.0 -0.97 -0.5233 -0.5277 3131725 CMLD2_000618 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P09 compound treatment 122000.0 6050.0 0.56 122800.0 8380.0 0.78 0.943 0.9867 3012184 CMLD2_000619 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P10 compound treatment 125200.0 9250.0 0.85 119200.0 4780.0 0.44 0.9152 0.9537 3131726 CMLD2_000620 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P11 mock treatment 125200.0 9250.0 0.85 117200.0 2780.0 0.26 0.7841 0.8817 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P12 mock treatment 113600.0 -2350.0 -0.22 117200.0 2780.0 0.26 0.0296 0.0881 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P13 compound treatment 124000.0 8050.0 0.74 120800.0 6380.0 0.59 0.942 0.9938 3131727 CMLD2_000621 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P14 compound treatment 95200.0 -20700.0 -1.91 91600.0 -22800.0 -2.12 -2.845 -0.9987 3012185 CMLD2_000622 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P15 compound treatment 101600.0 -14300.0 -1.32 84400.0 -30000.0 -2.78 -2.9007 -0.9419 3131728 CMLD2_000623 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P16 compound treatment 3200.0 -113000.0 -10.37 1600.0 -113000.0 -10.46 -14.7277 -1.0 3012186 CMLD2_000624 CC(C)(C)N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P17 compound treatment 116000.0 53.3 0.0 115200.0 781.0 0.07 0.0547 0.7533 3131729 CMLD2_000625 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P18 compound treatment 125600.0 9650.0 0.89 128000.0 13600.0 1.26 1.518 0.9854 3012187 CMLD2_000626 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4ccc(F)cc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P19 compound treatment 125600.0 9650.0 0.89 130400.0 16000.0 1.48 1.6753 0.97 3131730 CMLD2_000627 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P20 compound treatment 130400.0 14500.0 1.33 122000.0 7580.0 0.7 1.437 0.9556 3012188 CMLD2_000628 C[C@H]/1COC(=O)C\C=C\[C@@H](C)[C@H]2O[C@H](COC(=O)C\C=C1)[C@@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P21 compound treatment 128800.0 12900.0 1.18 129600.0 15200.0 1.41 1.831 0.9963 3131731 CMLD2_000629 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P22 compound treatment 133200.0 17300.0 1.59 134400.0 20000.0 1.85 2.4318 0.997 3012189 CMLD2_000630 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)COC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P23 compound treatment 122400.0 6450.0 0.59 124400.0 9980.0 0.93 1.0739 0.977 3131732 CMLD2_000631 CO[C@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](OCc3ccccc3)/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2110 P24 compound treatment 116800.0 853.0 0.08 116800.0 2380.0 0.22 0.2116 0.9032 3131733 CMLD2_000632 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A01 compound treatment 114800.0 -6670.0 -0.61 118000.0 -6400.0 -0.59 -0.8535 -0.9999 3012190 CMLD2_000633 CO[C@@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A02 compound treatment 126400.0 4930.0 0.45 120400.0 -4000.0 -0.37 0.0583 0.0995 3131321 CMLD2_000634 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A03 compound treatment 110000.0 -11500.0 -1.06 120800.0 -3600.0 -0.33 -0.9822 -0.8874 3131734 CMLD2_000635 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A04 compound treatment 110800.0 -10700.0 -0.98 111200.0 -13200.0 -1.22 -1.5594 -0.994 3131735 CMLD2_000636 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A05 compound treatment 102400.0 -19100.0 -1.75 103600.0 -20800.0 -1.93 -2.6039 -0.9989 3012191 CMLD2_000637 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A06 compound treatment 115200.0 -6270.0 -0.58 118000.0 -6400.0 -0.59 -0.8275 -0.9999 3131736 CMLD2_000638 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A07 compound treatment 109600.0 -11900.0 -1.09 118400.0 -6000.0 -0.56 -1.1655 -0.951 3012192 CMLD2_000639 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A08 compound treatment 114400.0 -7070.0 -0.65 123600.0 -800.0 -0.07 -0.5125 -0.7826 3131737 CMLD2_000640 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A09 compound treatment 93200.0 -28300.0 -2.6 95600.0 -28800.0 -2.67 -3.7266 -0.9999 3131738 CMLD2_000641 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)cc2)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A10 compound treatment 117200.0 -4270.0 -0.39 127200.0 2800.0 0.26 -0.0944 -0.2005 3012193 CMLD2_000642 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A11 compound treatment 118000.0 -3470.0 -0.32 116000.0 -8400.0 -0.78 -0.7765 -0.9226 3131739 CMLD2_000643 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A12 compound treatment 116800.0 -4670.0 -0.43 114800.0 -9600.0 -0.89 -0.9332 -0.9443 3012194 CMLD2_000644 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A13 mock treatment 116800.0 -4670.0 -0.43 129200.0 4800.0 0.44 0.0106 0.0172 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A14 mock treatment 116000.0 -5470.0 -0.5 116800.0 -7600.0 -0.7 -0.8541 -0.9864 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A15 compound treatment 99600.0 -21900.0 -2.01 98800.0 -25600.0 -2.37 -3.1006 -0.9966 3131740 CMLD2_000645 CCc1cc2CN(CC/C(=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A16 compound treatment 114000.0 -7470.0 -0.69 108800.0 -15600.0 -1.45 -1.5085 -0.9422 3131741 CMLD2_000646 CCc1cc2CN(CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A17 compound treatment 100800.0 -20700.0 -1.9 114000.0 -10400.0 -0.96 -2.0263 -0.9504 3012195 CMLD2_000647 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cc(no5)c6c(C)cc(C)cc6C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A18 compound treatment 100400.0 -21100.0 -1.94 112000.0 -12400.0 -1.15 -2.1834 -0.9689 3131860 CMLD2_000648 CO[C@H](/C=N/O[C@@H](C)c1cc(no1)c2c(C)cc(C)cc2C)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A19 compound treatment 115200.0 -6270.0 -0.58 114400.0 -10000.0 -0.93 -1.0635 -0.974 3012196 CMLD2_000649 C[C@H](ON=C(C)C)c1cc(no1)c2c(C)cc(C)cc2C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A20 compound treatment 122400.0 927.0 0.09 117600.0 -6800.0 -0.63 -0.3854 -0.606 3131861 CMLD2_000650 CO/N=C/[C@@H](C)[C@H](OCc1ccccc1)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A21 compound treatment 112400.0 -9070.0 -0.83 117200.0 -7200.0 -0.67 -1.0621 -0.9939 3131714 CMLD2_000651 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A22 compound treatment 114800.0 -6670.0 -0.61 120800.0 -3600.0 -0.33 -0.67 -0.959 3012197 CMLD2_000652 C[C@@H]1CC[C@@H]2N(C[C@@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A23 mock treatment 125200.0 3730.0 0.34 121200.0 -3200.0 -0.3 0.0326 0.072 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 A24 mock treatment 114400.0 -7070.0 -0.65 118800.0 -5600.0 -0.52 -0.8271 -0.9937 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B01 compound treatment 128000.0 6530.0 0.6 118400.0 -6000.0 -0.56 0.0313 0.0382 3131862 CMLD2_000653 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B02 compound treatment 133200.0 11700.0 1.08 130400.0 6000.0 0.56 1.156 0.9525 3011062 CMLD2_000654 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B03 compound treatment 120000.0 -1470.0 -0.14 115600.0 -8800.0 -0.82 -0.6726 -0.8134 3131863 CMLD2_000655 CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B04 compound treatment 112400.0 -9070.0 -0.83 116400.0 -8000.0 -0.74 -1.1145 -0.9983 3012198 CMLD2_000656 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B05 compound treatment 115200.0 -6270.0 -0.58 121200.0 -3200.0 -0.3 -0.6178 -0.9521 3131864 CMLD2_000657 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cc(no4)c5c(C)cc(C)cc5C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B06 compound treatment 129200.0 7730.0 0.71 128800.0 4400.0 0.41 0.7909 0.9652 3131865 CMLD2_000658 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cc(no2)c3c(C)cc(C)cc3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B07 compound treatment 122400.0 927.0 0.09 126400.0 2000.0 0.19 0.1913 0.9378 3012199 CMLD2_000659 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B08 compound treatment 120400.0 -1070.0 -0.1 122000.0 -2400.0 -0.22 -0.2271 -0.9332 3131866 CMLD2_000660 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B09 compound treatment 114400.0 -7070.0 -0.65 118800.0 -5600.0 -0.52 -0.8271 -0.9937 3131867 CMLD2_000661 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B10 compound treatment 125600.0 4130.0 0.38 118800.0 -5600.0 -0.52 -0.0986 -0.1534 3012228 CMLD2_000662 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B11 compound treatment 122000.0 527.0 0.05 118800.0 -5600.0 -0.52 -0.3328 -0.6384 3131868 CMLD2_000663 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B12 compound treatment 128400.0 6930.0 0.64 133600.0 9200.0 0.85 1.0535 0.9897 3130911 CMLD2_000664 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B13 mock treatment 123600.0 2130.0 0.2 130800.0 6400.0 0.59 0.5578 0.893 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B14 mock treatment 129600.0 8130.0 0.75 126400.0 2000.0 0.19 0.6597 0.8565 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B15 compound treatment 94400.0 -27100.0 -2.49 94400.0 -30000.0 -2.78 -3.7272 -0.9985 3131869 CMLD2_000665 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(CC)c(CC)cc3C2)C=C[C@@H]1Oc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B16 compound treatment 111200.0 -10300.0 -0.94 114800.0 -9600.0 -0.89 -1.2974 -0.9995 3012230 CMLD2_000666 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B17 compound treatment 118800.0 -2670.0 -0.25 120800.0 -3600.0 -0.33 -0.4098 -0.9887 3131870 CMLD2_000667 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B18 compound treatment 119200.0 -2270.0 -0.21 128400.0 4000.0 0.37 0.1143 0.2685 3012231 CMLD2_000668 CO[C@H](/C=N/OC[C@@H](C)[C@H](OCc1ccccc1)C(C)C)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B19 compound treatment 124800.0 3330.0 0.31 128000.0 3600.0 0.33 0.4523 0.9991 3131871 CMLD2_000669 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CON=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B20 compound treatment 122400.0 927.0 0.09 130400.0 6000.0 0.56 0.4535 0.8061 3012232 CMLD2_000670 CCc1cc2CN(CC/C(=N/OC)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B21 compound treatment 87200.0 -34300.0 -3.15 98400.0 -26000.0 -2.41 -3.9333 -0.9912 3131872 CMLD2_000671 C[C@@H]1CC[C@@H]2N(C[C@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B22 compound treatment 128000.0 6530.0 0.6 126000.0 1600.0 0.15 0.5294 0.8561 3131873 CMLD2_000672 COc1ccc(OC[C@H]2CN3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B23 mock treatment 130800.0 9330.0 0.86 142400.0 18000.0 1.67 1.7864 0.9522 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 B24 mock treatment 123600.0 2130.0 0.2 123600.0 -800.0 -0.07 0.0859 0.4105 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C01 compound treatment 120400.0 -1070.0 -0.1 120400.0 -4000.0 -0.37 -0.332 -0.8653 3012233 CMLD2_000673 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C02 compound treatment 115600.0 -5870.0 -0.54 123200.0 -1200.0 -0.11 -0.4607 -0.8352 3011181 CMLD2_000674 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C03 compound treatment 122800.0 1330.0 0.12 130800.0 6400.0 0.59 0.5057 0.8351 3131874 CMLD2_000675 CO[C@@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C04 compound treatment 104000.0 -17500.0 -1.61 106400.0 -18000.0 -1.67 -2.3163 -0.9998 3131875 CMLD2_000676 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C05 compound treatment 116000.0 -5470.0 -0.5 114800.0 -9600.0 -0.89 -0.9852 -0.9636 3012234 CMLD2_000677 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C06 compound treatment 120000.0 -1470.0 -0.14 133200.0 8800.0 0.82 0.4809 0.5816 3131876 CMLD2_000678 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C07 compound treatment 113200.0 -8270.0 -0.76 109600.0 -14800.0 -1.37 -1.5081 -0.9614 3131877 CMLD2_000679 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C08 compound treatment 105600.0 -15900.0 -1.46 109200.0 -15200.0 -1.41 -2.0287 -0.9998 3012270 CMLD2_000680 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)cc2)c6ccc(C)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C09 compound treatment 116000.0 -5470.0 -0.5 116000.0 -8400.0 -0.78 -0.9066 -0.9777 3131878 CMLD2_000681 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C10 compound treatment 116000.0 -5470.0 -0.5 114000.0 -10400.0 -0.96 -1.0376 -0.9541 3131879 CMLD2_000682 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C11 mock treatment 117200.0 -4270.0 -0.39 118400.0 -6000.0 -0.56 -0.6712 -0.9856 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C12 mock treatment 121200.0 -273.0 -0.03 122800.0 -1600.0 -0.15 -0.1227 -0.8154 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C13 compound treatment 102800.0 -18700.0 -1.72 114400.0 -10000.0 -0.93 -1.87 -0.9581 3012273 CMLD2_000683 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C14 compound treatment 119600.0 -1870.0 -0.17 125600.0 1200.0 0.11 -0.0432 -0.2106 3131994 CMLD2_000684 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C15 mock treatment 116000.0 -5470.0 -0.5 126800.0 2400.0 0.22 -0.1987 -0.361 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C16 mock treatment 122000.0 527.0 0.05 124400.0 0.0 0.0 0.0342 0.7071 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C17 compound treatment 107600.0 -13900.0 -1.28 114800.0 -9600.0 -0.89 -1.5316 -0.9845 3131995 CMLD2_000685 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C18 compound treatment 121200.0 -273.0 -0.03 127600.0 3200.0 0.3 0.1919 0.6448 3012274 CMLD2_000686 CO[C@H](/C=N/O[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C19 compound treatment 124000.0 2530.0 0.23 124400.0 0.0 0.0 0.1643 0.7071 3012275 CMLD2_000687 CC(=NO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C20 compound treatment 86400.0 -35100.0 -3.23 89200.0 -35200.0 -3.26 -4.5883 -1.0 3131996 CMLD2_000688 CO/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C21 compound treatment 126800.0 5330.0 0.49 124800.0 400.0 0.04 0.3727 0.7584 3011349 CMLD2_000689 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C22 compound treatment 114400.0 -7070.0 -0.65 119200.0 -5200.0 -0.48 -0.8009 -0.9891 3131997 CMLD2_000690 COc1ccc(OC[C@@H]2CC3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C23 mock treatment 133200.0 11700.0 1.08 132400.0 8000.0 0.74 1.2871 0.9833 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 C24 mock treatment 122000.0 527.0 0.05 124400.0 0.0 0.0 0.0342 0.7071 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D01 compound treatment 125200.0 3730.0 0.34 116400.0 -8000.0 -0.74 -0.282 -0.3451 3012277 CMLD2_000691 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D02 compound treatment 135600.0 14100.0 1.3 130800.0 6400.0 0.59 1.3383 0.9369 3131998 CMLD2_000692 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](CCSC)NC(=O)C\C=C\[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D03 compound treatment 118800.0 -2670.0 -0.25 120400.0 -4000.0 -0.37 -0.4361 -0.9801 3012278 CMLD2_000693 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)CCC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D04 compound treatment 124800.0 3330.0 0.31 127200.0 2800.0 0.26 0.3999 0.9966 3131999 CMLD2_000694 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D05 compound treatment 112400.0 -9070.0 -0.83 110800.0 -13600.0 -1.26 -1.4815 -0.98 3132000 CMLD2_000695 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D06 compound treatment 125600.0 4130.0 0.38 128800.0 4400.0 0.41 0.5568 0.9994 3012279 CMLD2_000696 CC(=O)OC[C@H]1O[C@H](C/C=N/OC2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D07 compound treatment 109200.0 -12300.0 -1.13 107200.0 -17200.0 -1.59 -1.9256 -0.9857 3132001 CMLD2_000697 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1Oc4ccc(OC)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D08 compound treatment 105600.0 -15900.0 -1.46 110400.0 -14000.0 -1.3 -1.95 -0.9983 3132002 CMLD2_000698 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/c2ccc(cc2)C(=O)N3[C@@H](CC[C@H](C)[C@H]3c4ccc(C)cc4)C(=O)OC)C=C[C@@H]1Oc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D09 compound treatment 100800.0 -20700.0 -1.9 106400.0 -18000.0 -1.67 -2.5244 -0.9979 3012280 CMLD2_000699 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc3ccc(OC)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D10 compound treatment 109600.0 -11900.0 -1.09 114800.0 -9600.0 -0.89 -1.4015 -0.9948 3132003 CMLD2_000700 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D11 mock treatment 115600.0 -5870.0 -0.54 115200.0 -9200.0 -0.85 -0.985 -0.9758 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D12 mock treatment 115600.0 -5870.0 -0.54 130400.0 6000.0 0.56 0.0112 0.0145 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D13 compound treatment 115600.0 -5870.0 -0.54 114400.0 -10000.0 -0.93 -1.0374 -0.967 3012281 CMLD2_000701 CC1(C)O[C@H]2O[C@H]([C@H](O)CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)[C@H](O)[C@H]2O1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D14 compound treatment 103600.0 -17900.0 -1.64 106000.0 -18400.0 -1.71 -2.3685 -0.9998 3132004 CMLD2_000702 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D15 mock treatment 103200.0 -18300.0 -1.68 108800.0 -15600.0 -1.45 -2.211 -0.9972 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D16 mock treatment 112800.0 -8670.0 -0.8 117200.0 -7200.0 -0.67 -1.036 -0.9961 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D17 compound treatment 106000.0 -15500.0 -1.42 102800.0 -21600.0 -2.0 -2.4221 -0.986 3132005 CMLD2_000703 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D18 compound treatment 126400.0 4930.0 0.45 129200.0 4800.0 0.44 0.635 1.0 3012283 CMLD2_000704 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D19 compound treatment 126400.0 4930.0 0.45 132000.0 7600.0 0.7 0.8186 0.9772 3132006 CMLD2_000705 C[C@@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D20 compound treatment 111200.0 -10300.0 -0.94 129200.0 4800.0 0.44 -0.3536 -0.3385 3012284 CMLD2_000706 CO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D21 compound treatment 111200.0 -10300.0 -0.94 118800.0 -5600.0 -0.52 -1.0352 -0.9602 3132007 CMLD2_000707 CCCC[C@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D22 compound treatment 123200.0 1730.0 0.16 120000.0 -4400.0 -0.41 -0.1761 -0.4023 3132008 CMLD2_000708 C[C@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D23 mock treatment 143200.0 21700.0 2.0 136400.0 12000.0 1.11 2.1997 0.9617 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 D24 mock treatment 127600.0 6130.0 0.56 122400.0 -2000.0 -0.19 0.2674 0.4507 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E01 mock treatment 117600.0 -3870.0 -0.36 123600.0 -800.0 -0.07 -0.3044 -0.8363 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E02 mock treatment 123200.0 1730.0 0.16 129600.0 5200.0 0.48 0.4531 0.8929 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E03 compound treatment 118800.0 -2670.0 -0.25 121200.0 -3200.0 -0.3 -0.3836 -0.9957 3012286 CMLD2_000709 CO[C@@H]1COC(=O)CCC[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E04 compound treatment 116400.0 -5070.0 -0.47 117200.0 -7200.0 -0.67 -0.8019 -0.9847 3132009 CMLD2_000710 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E05 compound treatment 114400.0 -7070.0 -0.65 108400.0 -16000.0 -1.48 -1.5087 -0.9316 3012287 CMLD2_000711 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E06 compound treatment 114000.0 -7470.0 -0.69 124400.0 0.0 0.0 -0.4861 -0.7071 3132010 CMLD2_000712 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E07 compound treatment 124000.0 2530.0 0.23 125600.0 1200.0 0.11 0.243 0.9431 3012333 CMLD2_000713 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E08 compound treatment 118800.0 -2670.0 -0.25 121600.0 -2800.0 -0.26 -0.3574 -0.9996 3132011 CMLD2_000714 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)cc2)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E09 mock treatment 113200.0 -8270.0 -0.76 116800.0 -7600.0 -0.7 -1.0362 -0.9993 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E10 mock treatment 112000.0 -9470.0 -0.87 119600.0 -4800.0 -0.44 -0.9308 -0.9513 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E11 compound treatment 95600.0 -25900.0 -2.38 102800.0 -21600.0 -2.0 -3.0986 -0.9963 3012334 CMLD2_000715 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E12 compound treatment 109200.0 -12300.0 -1.13 118000.0 -6400.0 -0.59 -1.2178 -0.9549 3132012 CMLD2_000716 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E13 compound treatment 105200.0 -16300.0 -1.5 115600.0 -8800.0 -0.82 -1.6352 -0.9592 3012337 CMLD2_000717 OC[C@H]1O[C@H](CC=C)C=C[C@@H]1O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E14 compound treatment 118000.0 -3470.0 -0.32 112800.0 -11600.0 -1.08 -0.9862 -0.8792 3132130 CMLD2_000718 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E15 compound treatment 108400.0 -13100.0 -1.2 120000.0 -4400.0 -0.41 -1.1387 -0.8967 3132131 CMLD2_000719 CCc1cc2CN(CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E16 compound treatment 106800.0 -14700.0 -1.35 107600.0 -16800.0 -1.56 -2.0555 -0.9975 3132132 CMLD2_000720 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6)c7ccccc7)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E17 mock treatment 116800.0 -4670.0 -0.43 112400.0 -12000.0 -1.11 -1.0905 -0.9145 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E18 mock treatment 113200.0 -8270.0 -0.76 114400.0 -10000.0 -0.93 -1.1935 -0.9952 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E19 compound treatment 118800.0 -2670.0 -0.25 118000.0 -6400.0 -0.59 -0.5934 -0.924 3012338 CMLD2_000721 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E20 mock treatment 117600.0 -3870.0 -0.36 124800.0 400.0 0.04 -0.2257 -0.6301 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E21 compound treatment 107600.0 -13900.0 -1.28 116000.0 -8400.0 -0.78 -1.4529 -0.9719 3131584 CMLD2_000722 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E22 compound treatment 113200.0 -8270.0 -0.76 118400.0 -6000.0 -0.56 -0.9314 -0.9881 3012339 CMLD2_000723 COC(=O)C/C=C/[C@@H](C)[C@H](OCc1cccc(c1)c2ccccc2)C3CCCCC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E23 mock treatment 128000.0 6530.0 0.6 132800.0 8400.0 0.78 0.9751 0.9917 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 E24 mock treatment 126000.0 4530.0 0.42 126400.0 2000.0 0.19 0.4255 0.9336 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F01 mock treatment 114800.0 -6670.0 -0.61 117600.0 -6800.0 -0.63 -0.8797 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F02 mock treatment 120400.0 -1070.0 -0.1 118400.0 -6000.0 -0.56 -0.4631 -0.8198 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F03 compound treatment 120000.0 -1470.0 -0.14 122400.0 -2000.0 -0.19 -0.2269 -0.9882 3132133 CMLD2_000724 C[C@H]1/C=C/CC(=O)OC[C@H](NS(=O)(=O)c2ccc(C)cc2)[C@@H](C)/C=C/CC(=O)OC[C@@H]1NS(=O)(=O)c3ccc(C)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F04 compound treatment 102000.0 -19500.0 -1.79 87200.0 -37200.0 -3.45 -3.7048 -0.9535 3012198 CMLD2_000725 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F05 compound treatment 114000.0 -7470.0 -0.69 117600.0 -6800.0 -0.63 -0.9318 -0.9991 3132134 CMLD2_000726 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F06 compound treatment 94800.0 -26700.0 -2.45 106800.0 -17600.0 -1.63 -2.8884 -0.9803 3012341 CMLD2_000727 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F07 compound treatment 110400.0 -11100.0 -1.02 114000.0 -10400.0 -0.96 -1.4019 -0.9996 3132135 CMLD2_000728 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F08 compound treatment 93200.0 -28300.0 -2.6 89600.0 -34800.0 -3.23 -4.1198 -0.9943 3132136 CMLD2_000729 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F09 mock treatment 110400.0 -11100.0 -1.02 111600.0 -12800.0 -1.19 -1.5592 -0.9971 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F10 mock treatment 116000.0 -5470.0 -0.5 106000.0 -18400.0 -1.71 -1.562 -0.8784 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F11 compound treatment 128800.0 7330.0 0.67 136800.0 12400.0 1.15 1.2893 0.9676 3012342 CMLD2_000730 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F12 compound treatment 109600.0 -11900.0 -1.09 112400.0 -12000.0 -1.11 -1.5588 -1.0 3132137 CMLD2_000731 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F13 compound treatment 100800.0 -20700.0 -1.9 104000.0 -20400.0 -1.89 -2.6817 -1.0 3010880 CMLD2_000732 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F14 compound treatment 117600.0 -3870.0 -0.36 105200.0 -19200.0 -1.78 -1.5103 -0.8322 3012343 CMLD2_000733 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F15 compound treatment 91600.0 -29900.0 -2.75 96000.0 -28400.0 -2.63 -3.8044 -0.9998 3132138 CMLD2_000734 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F16 compound treatment 96000.0 -25500.0 -2.34 106000.0 -18400.0 -1.71 -2.8628 -0.9878 3132139 CMLD2_000735 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1Oc6ccc(OC)cc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F17 mock treatment 114400.0 -7070.0 -0.65 112400.0 -12000.0 -1.11 -1.2466 -0.9674 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F18 mock treatment 108400.0 -13100.0 -1.2 122000.0 -2400.0 -0.22 -1.0076 -0.8239 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F19 compound treatment 108000.0 -13500.0 -1.24 105600.0 -18800.0 -1.74 -2.1085 -0.9861 3012344 CMLD2_000736 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F20 mock treatment 110400.0 -11100.0 -1.02 115600.0 -8800.0 -0.82 -1.297 -0.9939 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F21 compound treatment 107200.0 -14300.0 -1.31 113200.0 -11200.0 -1.04 -1.6625 -0.9932 3012345 CMLD2_000737 C[C@@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F22 compound treatment 116800.0 -4670.0 -0.43 118800.0 -5600.0 -0.52 -0.671 -0.9956 3132140 CMLD2_000738 CO[C@@H]([C@H](C)/C=C/CC(=O)OCCCc1ccccc1)C2CCCCC2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F23 mock treatment 120400.0 -1070.0 -0.1 122400.0 -2000.0 -0.19 -0.2009 -0.9565 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 F24 mock treatment 122400.0 927.0 0.09 119600.0 -4800.0 -0.44 -0.2543 -0.5614 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G01 compound treatment 124800.0 3330.0 0.31 114800.0 -9600.0 -0.89 -0.4128 -0.4387 3132141 CMLD2_000739 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G02 compound treatment 122800.0 1330.0 0.12 120800.0 -3600.0 -0.33 -0.1497 -0.4213 3012346 CMLD2_000740 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G03 mock treatment 124400.0 2930.0 0.27 126000.0 1600.0 0.15 0.2952 0.9605 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G04 mock treatment 119200.0 -2270.0 -0.21 122400.0 -2000.0 -0.19 -0.279 -0.9982 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G05 compound treatment 102400.0 -19100.0 -1.75 111200.0 -13200.0 -1.22 -2.1057 -0.9845 3132142 CMLD2_000741 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1Oc3ccc(OC)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G06 compound treatment 114000.0 -7470.0 -0.69 127600.0 3200.0 0.3 -0.2764 -0.3691 3012347 CMLD2_000742 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G07 mock treatment 116000.0 -5470.0 -0.5 117200.0 -7200.0 -0.67 -0.8279 -0.9903 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G08 mock treatment 122400.0 927.0 0.09 125600.0 1200.0 0.11 0.1389 0.9914 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G09 compound treatment 108800.0 -12700.0 -1.17 110800.0 -13600.0 -1.26 -1.7157 -0.9992 3132143 CMLD2_000743 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G10 compound treatment 116000.0 -5470.0 -0.5 111600.0 -12800.0 -1.19 -1.1949 -0.9271 3132144 CMLD2_000744 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C\3/[C@H](O)[C@H](Oc4ccc(OC)cc34)c5cccc(OC)c5)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G11 compound treatment 118400.0 -3070.0 -0.28 122000.0 -2400.0 -0.22 -0.3572 -0.993 3132145 CMLD2_000745 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G12 compound treatment 103600.0 -17900.0 -1.64 105600.0 -18800.0 -1.74 -2.3947 -0.9996 3012401 CMLD2_000746 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G13 compound treatment 114400.0 -7070.0 -0.65 118400.0 -6000.0 -0.56 -0.8533 -0.9969 3132146 CMLD2_000747 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@@H]7COC[C@H]7O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G14 compound treatment 94400.0 -27100.0 -2.49 93600.0 -30800.0 -2.85 -3.7796 -0.9977 3012403 CMLD2_000748 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G15 compound treatment 109600.0 -11900.0 -1.09 106000.0 -18400.0 -1.71 -1.9783 -0.9768 3132147 CMLD2_000749 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G16 compound treatment 106000.0 -15500.0 -1.42 106400.0 -18000.0 -1.67 -2.1862 -0.9969 3012404 CMLD2_000750 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G17 compound treatment 90800.0 -30700.0 -2.82 97600.0 -26800.0 -2.48 -3.7516 -0.998 3132148 CMLD2_000751 CO[C@H](/C=N/OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G18 compound treatment 118800.0 -2670.0 -0.25 133200.0 8800.0 0.82 0.4029 0.4729 3132267 CMLD2_000752 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CON=C(C)C)c3ccccc3)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G19 mock treatment 119600.0 -1870.0 -0.17 118400.0 -6000.0 -0.56 -0.5151 -0.8847 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G20 mock treatment 126000.0 4530.0 0.42 126000.0 1600.0 0.15 0.3993 0.9034 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G21 compound treatment 123200.0 1730.0 0.16 131200.0 6800.0 0.63 0.558 0.8584 3012405 CMLD2_000753 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G22 compound treatment 104800.0 -16700.0 -1.53 109600.0 -14800.0 -1.37 -2.0545 -0.9985 3132268 CMLD2_000754 CO[C@H]([C@@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)CO)C2CCCCC2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G23 mock treatment 119600.0 -1870.0 -0.17 127200.0 2800.0 0.26 0.0617 0.1979 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 G24 mock treatment 124400.0 2930.0 0.27 130400.0 6000.0 0.56 0.5836 0.9445 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H01 compound treatment 118400.0 -3070.0 -0.28 121200.0 -3200.0 -0.3 -0.4096 -0.9997 3012408 CMLD2_000755 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H02 compound treatment 124800.0 3330.0 0.31 128400.0 4000.0 0.37 0.4785 0.9955 3132269 CMLD2_000756 C[C@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H03 mock treatment 125200.0 3730.0 0.34 129600.0 5200.0 0.48 0.5832 0.9861 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H04 mock treatment 123200.0 1730.0 0.16 121200.0 -3200.0 -0.3 -0.0974 -0.2896 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H05 compound treatment 117200.0 -4270.0 -0.39 129600.0 5200.0 0.48 0.0629 0.1011 3132270 CMLD2_000757 CC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H06 compound treatment 124400.0 2930.0 0.27 122000.0 -2400.0 -0.22 0.033 0.0946 3012411 CMLD2_000758 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCCCc4nc(C)c(C)cc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H07 mock treatment 118800.0 -2670.0 -0.25 118400.0 -6000.0 -0.56 -0.5671 -0.9327 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H08 compound treatment 114800.0 -6670.0 -0.61 122400.0 -2000.0 -0.19 -0.5651 -0.8813 3132271 CMLD2_000759 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H09 compound treatment 117200.0 -4270.0 -0.39 110000.0 -14400.0 -1.33 -1.2218 -0.8781 3132272 CMLD2_000760 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H10 compound treatment 110800.0 -10700.0 -0.98 116400.0 -8000.0 -0.74 -1.2186 -0.9904 3012412 CMLD2_000761 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C\2/[C@H](O)[C@H](Oc3ccc(OC)cc23)c4cccc(OC)c4)C=C[C@@H]1Oc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H11 compound treatment 117200.0 -4270.0 -0.39 115200.0 -9200.0 -0.85 -0.8809 -0.9382 3132273 CMLD2_000762 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H12 compound treatment 118000.0 -3470.0 -0.32 110400.0 -14000.0 -1.3 -1.1435 -0.8557 3132274 CMLD2_000763 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H13 compound treatment 106000.0 -15500.0 -1.42 112000.0 -12400.0 -1.15 -1.8192 -0.9944 3012414 CMLD2_000764 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H14 compound treatment 93200.0 -28300.0 -2.6 94400.0 -30000.0 -2.78 -3.8052 -0.9994 3132275 CMLD2_000765 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)COCc2ccco2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H15 compound treatment 108800.0 -12700.0 -1.17 108000.0 -16400.0 -1.52 -1.8992 -0.9914 3012415 CMLD2_000766 CCc1cc2CN(CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H16 compound treatment 112000.0 -9470.0 -0.87 118400.0 -6000.0 -0.56 -1.0094 -0.9765 3132276 CMLD2_000767 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H17 compound treatment 97600.0 -23900.0 -2.2 100000.0 -24400.0 -2.26 -3.152 -0.9999 3132277 CMLD2_000768 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc2ccc(OC)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H18 compound treatment 108000.0 -13500.0 -1.24 117200.0 -7200.0 -0.67 -1.3483 -0.9578 3012416 CMLD2_000769 CCCNC(=O)OC[C@H]1O[C@H](CCON=C(C)C)C=C[C@@H]1Oc2ccc(OC)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H19 mock treatment 123600.0 2130.0 0.2 123600.0 -800.0 -0.07 0.0859 0.4105 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H20 mock treatment 124800.0 3330.0 0.31 124000.0 -400.0 -0.04 0.1901 0.6169 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H21 compound treatment 114800.0 -6670.0 -0.61 122400.0 -2000.0 -0.19 -0.5651 -0.8813 3132278 CMLD2_000770 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H22 compound treatment 117600.0 -3870.0 -0.36 129200.0 4800.0 0.44 0.0627 0.1099 3012418 CMLD2_000771 CO[C@H]1[C@H](C)/C(=C\CCOCC#CC)/c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H23 mock treatment 132000.0 10500.0 0.97 133200.0 8800.0 0.82 1.2614 0.9964 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 H24 mock treatment 122800.0 1330.0 0.12 124400.0 0.0 0.0 0.0863 0.7071 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I01 compound treatment 124400.0 2930.0 0.27 123200.0 -1200.0 -0.11 0.1117 0.3835 3132279 CMLD2_000772 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I02 compound treatment 126800.0 5330.0 0.49 123600.0 -800.0 -0.07 0.294 0.5933 3012419 CMLD2_000773 C[C@@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I03 compound treatment 114800.0 -6670.0 -0.61 124400.0 0.0 0.0 -0.4341 -0.7071 3132280 CMLD2_000774 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)c6ccccc6)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I04 compound treatment 110000.0 -11500.0 -1.06 107200.0 -17200.0 -1.59 -1.8736 -0.9799 3132281 CMLD2_000775 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I05 mock treatment 113200.0 -8270.0 -0.76 128800.0 4400.0 0.41 -0.2497 -0.2892 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I06 mock treatment 122400.0 927.0 0.09 129200.0 4800.0 0.44 0.3749 0.8275 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I07 compound treatment 110800.0 -10700.0 -0.98 112800.0 -11600.0 -1.08 -1.4545 -0.999 3012420 CMLD2_000776 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I08 compound treatment 104800.0 -16700.0 -1.53 110800.0 -13600.0 -1.26 -1.9759 -0.9953 3132282 CMLD2_000777 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)cc2)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I09 compound treatment 110800.0 -10700.0 -0.98 109600.0 -14800.0 -1.37 -1.6643 -0.9865 3012421 CMLD2_000778 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I10 compound treatment 141600.0 20100.0 1.85 147200.0 22800.0 2.11 2.8034 0.9978 3132283 CMLD2_000779 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I11 compound treatment 109200.0 -12300.0 -1.13 110400.0 -14000.0 -1.3 -1.7159 -0.9976 3012422 CMLD2_000780 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@H]4O[C@@H](C=C[C@@H]4Oc5ccc(OC)cc5)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I12 compound treatment 113600.0 -7870.0 -0.72 116400.0 -8000.0 -0.74 -1.0364 -0.9999 3012473 CMLD2_000781 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I13 compound treatment 38000.0 -83500.0 -7.68 38400.0 -86000.0 -7.97 -11.0659 -0.9998 3132284 CMLD2_000782 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cc(no6)c7c(C)cc(C)cc7C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I14 compound treatment 113600.0 -7870.0 -0.72 108000.0 -16400.0 -1.52 -1.587 -0.9425 3012475 CMLD2_000783 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I15 compound treatment 105600.0 -15900.0 -1.46 105200.0 -19200.0 -1.78 -2.2909 -0.9952 3132285 CMLD2_000784 CCc1cc2CN(CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I16 compound treatment 114400.0 -7070.0 -0.65 112000.0 -12400.0 -1.15 -1.2728 -0.9637 3012476 CMLD2_000785 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I17 compound treatment 110800.0 -10700.0 -0.98 126000.0 1600.0 0.15 -0.5894 -0.5936 3132408 CMLD2_000786 CO[C@H](/C=N/OCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I18 compound treatment 117600.0 -3870.0 -0.36 125600.0 1200.0 0.11 -0.1733 -0.4643 3012477 CMLD2_000787 CC(=NOCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I19 compound treatment 117200.0 -4270.0 -0.39 122800.0 -1600.0 -0.15 -0.3828 -0.9112 3132409 CMLD2_000788 CO/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I20 mock treatment 123600.0 2130.0 0.2 124000.0 -400.0 -0.04 0.1121 0.5631 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I21 mock treatment 129600.0 8130.0 0.75 130800.0 6400.0 0.59 0.948 0.9934 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I22 mock treatment 131600.0 10100.0 0.93 140800.0 16400.0 1.52 1.7335 0.9724 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I23 mock treatment 130400.0 8930.0 0.82 134800.0 10400.0 0.96 1.2622 0.9968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 I24 mock treatment 130400.0 8930.0 0.82 125200.0 800.0 0.07 0.633 0.7678 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J01 compound treatment 124000.0 2530.0 0.23 122400.0 -2000.0 -0.19 0.0332 0.1118 3132410 CMLD2_000789 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)CCC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J02 compound treatment 122800.0 1330.0 0.12 129200.0 4800.0 0.44 0.4009 0.8689 3012478 CMLD2_000790 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J03 compound treatment 110000.0 -11500.0 -1.06 118800.0 -5600.0 -0.52 -1.1133 -0.9466 3132411 CMLD2_000791 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J04 compound treatment 116000.0 -5470.0 -0.5 124000.0 -400.0 -0.04 -0.3822 -0.7571 3132412 CMLD2_000792 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J05 mock treatment 114800.0 -6670.0 -0.61 122400.0 -2000.0 -0.19 -0.5651 -0.8813 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J06 mock treatment 121200.0 -273.0 -0.03 123200.0 -1200.0 -0.11 -0.0964 -0.8457 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J07 compound treatment 110400.0 -11100.0 -1.02 121200.0 -3200.0 -0.3 -0.93 -0.8766 3012479 CMLD2_000793 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J08 compound treatment 109200.0 -12300.0 -1.13 94800.0 -29600.0 -2.74 -2.7383 -0.923 3012480 CMLD2_000794 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)COCc3ccco3)cc2)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J09 compound treatment 114400.0 -7070.0 -0.65 113600.0 -10800.0 -1.0 -1.1679 -0.9782 3132413 CMLD2_000795 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J10 compound treatment 134800.0 13300.0 1.23 138000.0 13600.0 1.26 1.7582 0.9999 3132414 CMLD2_000796 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCCc5nc(C)c(C)cc45)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J11 compound treatment 103200.0 -18300.0 -1.68 101600.0 -22800.0 -2.11 -2.6829 -0.9936 3132415 CMLD2_000797 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(CC)C4=O)C=C[C@@H]1Oc5ccc(OC)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J12 compound treatment 110400.0 -11100.0 -1.02 118400.0 -6000.0 -0.56 -1.1135 -0.9595 3012481 CMLD2_000798 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J13 compound treatment 89600.0 -31900.0 -2.93 88000.0 -36400.0 -3.37 -4.4589 -0.9976 3132416 CMLD2_000799 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J14 compound treatment 100400.0 -21100.0 -1.94 105200.0 -19200.0 -1.78 -2.6291 -0.9991 3012482 CMLD2_000800 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J15 compound treatment 103600.0 -17900.0 -1.64 106000.0 -18400.0 -1.71 -2.3685 -0.9998 3132417 CMLD2_000801 CCc1cc2CN(CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J16 compound treatment 111200.0 -10300.0 -0.94 111200.0 -13200.0 -1.22 -1.5334 -0.9919 3012484 CMLD2_000802 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J17 compound treatment 106000.0 -15500.0 -1.42 114000.0 -10400.0 -0.96 -1.6881 -0.982 3132418 CMLD2_000803 CO[C@H](/C=N/OC(C)CN1CCCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J18 compound treatment 118400.0 -3070.0 -0.28 116400.0 -8000.0 -0.74 -0.7242 -0.9126 3012486 CMLD2_000804 CC(CN1CCCCc2nc(C)c(C)cc12)ON=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J19 compound treatment 110000.0 -11500.0 -1.06 126400.0 2000.0 0.19 -0.6152 -0.5741 3132419 CMLD2_000805 CO/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J20 mock treatment 121200.0 -273.0 -0.03 124000.0 -400.0 -0.04 -0.044 -0.9821 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J21 mock treatment 118000.0 -3470.0 -0.32 126800.0 2400.0 0.22 -0.0686 -0.1763 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J22 mock treatment 127600.0 6130.0 0.56 133600.0 9200.0 0.85 1.0015 0.9798 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J23 mock treatment 128400.0 6930.0 0.64 132000.0 7600.0 0.7 0.9486 0.9987 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 J24 mock treatment 131200.0 9730.0 0.89 121200.0 -3200.0 -0.3 0.4229 0.4487 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K01 compound treatment 122400.0 927.0 0.09 125600.0 1200.0 0.11 0.1389 0.9914 3132420 CMLD2_000806 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K02 compound treatment 131200.0 9730.0 0.89 127200.0 2800.0 0.26 0.8162 0.8761 3012487 CMLD2_000807 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K03 compound treatment 114400.0 -7070.0 -0.65 112000.0 -12400.0 -1.15 -1.2728 -0.9637 3132421 CMLD2_000808 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K04 compound treatment 112400.0 -9070.0 -0.83 116000.0 -8400.0 -0.78 -1.1407 -0.9994 3132422 CMLD2_000809 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K05 compound treatment 108000.0 -13500.0 -1.24 118800.0 -5600.0 -0.52 -1.2434 -0.9254 3012488 CMLD2_000810 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K06 compound treatment 114400.0 -7070.0 -0.65 117600.0 -6800.0 -0.63 -0.9058 -0.9999 3132423 CMLD2_000811 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K07 mock treatment 120800.0 -673.0 -0.06 118800.0 -5600.0 -0.52 -0.4108 -0.7859 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K08 mock treatment 110800.0 -10700.0 -0.98 115600.0 -8800.0 -0.82 -1.271 -0.9958 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K09 compound treatment 116800.0 -4670.0 -0.43 113600.0 -10800.0 -1.0 -1.0118 -0.9287 3132424 CMLD2_000812 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K10 compound treatment 131600.0 10100.0 0.93 127200.0 2800.0 0.26 0.8422 0.8709 3011824 CMLD2_000813 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCc5nc(C)c(C)cc45)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K11 compound treatment 107200.0 -14300.0 -1.31 111600.0 -12800.0 -1.19 -1.7673 -0.9987 3132425 CMLD2_000814 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K12 compound treatment 98000.0 -23500.0 -2.16 94000.0 -30400.0 -2.82 -3.5193 -0.9914 3132426 CMLD2_000815 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)c8ccccc8)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K13 compound treatment 111200.0 -10300.0 -0.94 114800.0 -9600.0 -0.89 -1.2974 -0.9995 3011825 CMLD2_000816 CC(=O)OC[C@H]1O[C@@H](O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K14 compound treatment 102400.0 -19100.0 -1.75 106000.0 -18400.0 -1.71 -2.4466 -0.9999 3132547 CMLD2_000817 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K15 mock treatment 118400.0 -3070.0 -0.28 122400.0 -2000.0 -0.19 -0.331 -0.9791 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K16 mock treatment 116800.0 -4670.0 -0.43 121600.0 -2800.0 -0.26 -0.4875 -0.9708 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K17 compound treatment 115600.0 -5870.0 -0.54 128400.0 4000.0 0.37 -0.1199 -0.1829 3011826 CMLD2_000818 CO[C@H](/C=N/OC(C)CN1CCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K18 compound treatment 117600.0 -3870.0 -0.36 122000.0 -2400.0 -0.22 -0.4092 -0.9743 3132548 CMLD2_000819 CC(CN1CCCc2nc(C)c(C)cc12)ON=C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K19 compound treatment 115200.0 -6270.0 -0.58 115600.0 -8800.0 -0.82 -0.9848 -0.9856 3011827 CMLD2_000820 CO/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K20 compound treatment 112000.0 -9470.0 -0.87 123200.0 -1200.0 -0.11 -0.6948 -0.7909 3131977 CMLD2_000821 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K21 compound treatment 108000.0 -13500.0 -1.24 115200.0 -9200.0 -0.85 -1.4793 -0.9834 3132549 CMLD2_000822 C[C@@H]1CC[C@@H]2N(C[C@H](Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K22 compound treatment 119200.0 -2270.0 -0.21 127600.0 3200.0 0.3 0.0619 0.1705 3132550 CMLD2_000823 CCO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K23 mock treatment 123600.0 2130.0 0.2 130800.0 6400.0 0.59 0.5578 0.893 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 K24 mock treatment 118800.0 -2670.0 -0.25 130000.0 5600.0 0.52 0.1931 0.3363 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L01 compound treatment 118000.0 -3470.0 -0.32 123600.0 -800.0 -0.07 -0.2784 -0.8487 3011828 CMLD2_000824 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L02 compound treatment 122800.0 1330.0 0.12 129200.0 4800.0 0.44 0.4009 0.8689 3132551 CMLD2_000825 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L03 compound treatment 118000.0 -3470.0 -0.32 122800.0 -1600.0 -0.15 -0.3308 -0.9391 3011829 CMLD2_000826 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L04 compound treatment 125600.0 4130.0 0.38 134400.0 10000.0 0.93 0.9238 0.9223 3132552 CMLD2_000827 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L05 compound treatment 117200.0 -4270.0 -0.39 116000.0 -8400.0 -0.78 -0.8285 -0.9499 3132553 CMLD2_000828 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L06 compound treatment 126400.0 4930.0 0.45 125200.0 800.0 0.07 0.3729 0.812 3011830 CMLD2_000829 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L07 mock treatment 120000.0 -1470.0 -0.14 124800.0 400.0 0.04 -0.0696 -0.4955 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L08 mock treatment 123600.0 2130.0 0.2 125600.0 1200.0 0.11 0.217 0.9642 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L09 compound treatment 111600.0 -9870.0 -0.91 120800.0 -3600.0 -0.33 -0.8781 -0.9076 3132554 CMLD2_000830 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)COCc2ccco2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L10 compound treatment 153200.0 31700.0 2.92 151600.0 27200.0 2.52 3.8463 0.9973 3011831 CMLD2_000831 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L11 compound treatment 117200.0 -4270.0 -0.39 111200.0 -13200.0 -1.22 -1.1431 -0.8895 3132555 CMLD2_000832 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCCc5nc(C)c(C)cc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L12 compound treatment 83200.0 -38300.0 -3.52 74800.0 -49600.0 -4.6 -5.7403 -0.9913 3132556 CMLD2_000833 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1Oc7ccc(OC)cc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L13 compound treatment 116800.0 -4670.0 -0.43 122400.0 -2000.0 -0.19 -0.4351 -0.9293 3011832 CMLD2_000834 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L14 compound treatment 120400.0 -1070.0 -0.1 117600.0 -6800.0 -0.63 -0.5155 -0.808 3132557 CMLD2_000835 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L15 mock treatment 111200.0 -10300.0 -0.94 116400.0 -8000.0 -0.74 -1.1925 -0.9928 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L16 mock treatment 121600.0 127.0 0.01 126000.0 1600.0 0.15 0.1131 0.7603 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L17 compound treatment 118000.0 -3470.0 -0.32 109600.0 -14800.0 -1.37 -1.1959 -0.8491 3132558 CMLD2_000836 CO[C@H](/C=N/OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L18 compound treatment 119600.0 -1870.0 -0.17 119200.0 -5200.0 -0.48 -0.4627 -0.9039 3011833 CMLD2_000837 CC(=NOC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L19 compound treatment 112000.0 -9470.0 -0.87 120000.0 -4400.0 -0.41 -0.9046 -0.9402 3011834 CMLD2_000838 CO/N=C/c1ccc(cc1)C(=O)N2[C@@H](CC[C@H](C)[C@H]2c3ccc(C)cc3)C(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L20 compound treatment 119600.0 -1870.0 -0.17 130800.0 6400.0 0.59 0.2976 0.4818 3132559 CMLD2_000839 CCC(=O)[C@]1(O)[C@H]2CCOC(=O)C2=C3N(Cc4ccccc4)C(=C([C@H](N3C1=O)c5ccccc5)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L21 compound treatment 119600.0 -1870.0 -0.17 123600.0 -800.0 -0.07 -0.1743 -0.929 3132529 CMLD2_000840 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L22 compound treatment 123200.0 1730.0 0.16 132400.0 8000.0 0.74 0.6366 0.8395 3011835 CMLD2_000841 CO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)C(=O)C)[C@@H](C)[C@H](OC)c1ccccc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L23 mock treatment 130800.0 9330.0 0.86 133200.0 8800.0 0.82 1.1834 0.9997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 L24 mock treatment 126400.0 4930.0 0.45 130400.0 6000.0 0.56 0.7137 0.9948 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M01 compound treatment 120000.0 -1470.0 -0.14 119600.0 -4800.0 -0.44 -0.4104 -0.8825 3132560 CMLD2_000842 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)CCC[C@H]1C)[C@@H](O)C=C2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M02 compound treatment 114800.0 -6670.0 -0.61 122000.0 -2400.0 -0.22 -0.5914 -0.9057 3011836 CMLD2_000843 C[C@H]/1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C\C=C1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M03 compound treatment 120400.0 -1070.0 -0.1 118400.0 -6000.0 -0.56 -0.4631 -0.8198 3132561 CMLD2_000844 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M04 compound treatment 114400.0 -7070.0 -0.65 116800.0 -7600.0 -0.7 -0.9582 -0.9992 3132562 CMLD2_000845 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M05 compound treatment 116400.0 -5070.0 -0.47 121200.0 -3200.0 -0.3 -0.5397 -0.9761 3011870 CMLD2_000846 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M06 compound treatment 119200.0 -2270.0 -0.21 123200.0 -1200.0 -0.11 -0.2265 -0.9563 3132563 CMLD2_000847 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M07 compound treatment 120400.0 -1070.0 -0.1 115600.0 -8800.0 -0.82 -0.6466 -0.787 3011871 CMLD2_000848 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M08 compound treatment 128400.0 6930.0 0.64 126800.0 2400.0 0.22 0.6078 0.9007 3132564 CMLD2_000849 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M09 mock treatment 111600.0 -9870.0 -0.91 114800.0 -9600.0 -0.89 -1.2714 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M10 mock treatment 114800.0 -6670.0 -0.61 114800.0 -9600.0 -0.89 -1.0633 -0.9836 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M11 compound treatment 116000.0 -5470.0 -0.5 108800.0 -15600.0 -1.45 -1.3785 -0.9003 3011872 CMLD2_000850 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCc5nc(C)c(C)cc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M12 compound treatment 111600.0 -9870.0 -0.91 109600.0 -14800.0 -1.37 -1.6122 -0.9799 3132565 CMLD2_000851 CC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M13 mock treatment 122400.0 927.0 0.09 120800.0 -3600.0 -0.33 -0.1757 -0.5101 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M14 mock treatment 119600.0 -1870.0 -0.17 124000.0 -400.0 -0.04 -0.1481 -0.84 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M15 compound treatment 112800.0 -8670.0 -0.8 118400.0 -6000.0 -0.56 -0.9574 -0.9844 3132566 CMLD2_000852 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M16 compound treatment 103600.0 -17900.0 -1.64 111200.0 -13200.0 -1.22 -2.0277 -0.9894 3011873 CMLD2_000853 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M17 compound treatment 116800.0 -4670.0 -0.43 126000.0 1600.0 0.15 -0.1991 -0.4378 3130490 CMLD2_000854 CO[C@H](/C=N/O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M18 compound treatment 122000.0 527.0 0.05 118800.0 -5600.0 -0.52 -0.3328 -0.6384 3011875 CMLD2_000855 CC(=NOC1C=C[C@@H](CC=C)O[C@@H]1CO)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M19 compound treatment 118400.0 -3070.0 -0.28 120400.0 -4000.0 -0.37 -0.4621 -0.991 3130491 CMLD2_000856 CO/N=C/[C@@H](NS(=O)(=O)c1ccc(C)cc1)[C@H](C)\C=C\CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M20 compound treatment 129200.0 7730.0 0.71 130000.0 5600.0 0.52 0.8696 0.9881 3132404 CMLD2_000857 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M21 compound treatment 111600.0 -9870.0 -0.91 115600.0 -8800.0 -0.82 -1.219 -0.9986 3011876 CMLD2_000858 C[C@H]1CC[C@@H]2N(C[C@@H](CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M22 compound treatment 120000.0 -1470.0 -0.14 126800.0 2400.0 0.22 0.0615 0.2359 3130492 CMLD2_000859 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1ccccc1Br 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M23 mock treatment 137200.0 15700.0 1.45 133200.0 8800.0 0.82 1.5997 0.9632 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 M24 mock treatment 118800.0 -2670.0 -0.25 130000.0 5600.0 0.52 0.1931 0.3363 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N01 compound treatment 118800.0 -2670.0 -0.25 130000.0 5600.0 0.52 0.1931 0.3363 3130493 CMLD2_000860 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)CCC[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N02 compound treatment 122400.0 927.0 0.09 130000.0 5600.0 0.52 0.4273 0.8123 3011877 CMLD2_000861 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N03 compound treatment 121600.0 127.0 0.01 115600.0 -8800.0 -0.82 -0.5685 -0.6969 3130494 CMLD2_000862 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)c5ccccc5)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N04 compound treatment 98800.0 -22700.0 -2.09 102800.0 -21600.0 -2.0 -2.8904 -0.9998 3130495 CMLD2_000863 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N05 compound treatment 126000.0 4530.0 0.42 126000.0 1600.0 0.15 0.3993 0.9034 3011878 CMLD2_000864 CC(=O)OC[C@H]1O[C@H](C/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N06 compound treatment 127600.0 6130.0 0.56 126800.0 2400.0 0.22 0.5558 0.9173 3130496 CMLD2_000865 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N07 compound treatment 124400.0 2930.0 0.27 132000.0 7600.0 0.7 0.6885 0.9129 3011879 CMLD2_000866 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N08 compound treatment 96400.0 -25100.0 -2.31 85600.0 -38800.0 -3.6 -4.1739 -0.9769 3130497 CMLD2_000867 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N09 mock treatment 115600.0 -5870.0 -0.54 126400.0 2000.0 0.19 -0.2509 -0.4393 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N10 mock treatment 130400.0 8930.0 0.82 124800.0 400.0 0.04 0.6068 0.7383 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N11 compound treatment 117600.0 -3870.0 -0.36 122400.0 -2000.0 -0.19 -0.383 -0.9537 3011881 CMLD2_000868 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N12 compound treatment 106800.0 -14700.0 -1.35 102000.0 -22400.0 -2.08 -2.4225 -0.9782 3130498 CMLD2_000869 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N13 mock treatment 116000.0 -5470.0 -0.5 116400.0 -8000.0 -0.74 -0.8803 -0.9822 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N14 mock treatment 124400.0 2930.0 0.27 124000.0 -400.0 -0.04 0.1641 0.604 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N15 compound treatment 118000.0 -3470.0 -0.32 104800.0 -19600.0 -1.82 -1.5105 -0.8189 3130499 CMLD2_000870 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N16 compound treatment 111600.0 -9870.0 -0.91 121200.0 -3200.0 -0.3 -0.8519 -0.8917 3011882 CMLD2_000871 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N17 compound treatment 116800.0 -4670.0 -0.43 112000.0 -12400.0 -1.15 -1.1167 -0.91 3130500 CMLD2_000872 CO[C@H](/C=N/OC[C@@H](O)COCc1ccco1)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N18 compound treatment 127200.0 5730.0 0.53 127600.0 3200.0 0.3 0.5822 0.9631 3011884 CMLD2_000873 CC(=NOC[C@@H](O)COCc1ccco1)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N19 compound treatment 160000.0 38500.0 3.54 160800.0 36400.0 3.37 4.8916 0.9997 3130501 CMLD2_000874 CO/N=C\1/[C@H](O)[C@H](Oc2ccc(OC)cc12)c3cccc(OC)c3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N20 compound treatment 121600.0 127.0 0.01 129600.0 5200.0 0.48 0.349 0.724 3131849 CMLD2_000875 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N21 compound treatment 120000.0 -1470.0 -0.14 117600.0 -6800.0 -0.63 -0.5415 -0.84 3011885 CMLD2_000876 C[C@@H]1CC[C@@H]2N(C[C@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N22 compound treatment 126800.0 5330.0 0.49 127600.0 3200.0 0.3 0.5562 0.9711 3130502 CMLD2_000877 CO[C@@H]([C@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)/C=C/CC(=O)OC)C2CCCCC2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N23 mock treatment 132400.0 10900.0 1.01 134000.0 9600.0 0.89 1.3399 0.9982 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 N24 mock treatment 118400.0 -3070.0 -0.28 125600.0 1200.0 0.11 -0.1213 -0.3991 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O01 compound treatment 124400.0 2930.0 0.27 126400.0 2000.0 0.19 0.3214 0.9834 3011886 CMLD2_000878 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O02 compound treatment 123600.0 2130.0 0.2 132400.0 8000.0 0.74 0.6627 0.8641 3130503 CMLD2_000879 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O03 compound treatment 112800.0 -8670.0 -0.8 119600.0 -4800.0 -0.44 -0.8787 -0.962 3130504 CMLD2_000880 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O04 compound treatment 108800.0 -12700.0 -1.17 110400.0 -14000.0 -1.3 -1.7419 -0.9986 3130505 CMLD2_000881 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O05 compound treatment 120400.0 -1070.0 -0.1 127600.0 3200.0 0.3 0.1399 0.4476 3130506 CMLD2_000882 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)COCc2ccco2)C=C[C@@H]1OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O06 compound treatment 98800.0 -22700.0 -2.09 111600.0 -12800.0 -1.19 -2.3137 -0.9643 3011921 CMLD2_000883 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O07 compound treatment 118000.0 -3470.0 -0.32 120800.0 -3600.0 -0.33 -0.4619 -0.9998 3130507 CMLD2_000884 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O08 compound treatment 104400.0 -17100.0 -1.57 107600.0 -16800.0 -1.56 -2.2116 -1.0 3130508 CMLD2_000885 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)cc2)c5ccc(C)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O09 compound treatment 121600.0 127.0 0.01 118400.0 -6000.0 -0.56 -0.385 -0.6922 3011922 CMLD2_000886 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O10 compound treatment 126400.0 4930.0 0.45 128000.0 3600.0 0.33 0.5564 0.9887 3130509 CMLD2_000887 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O11 mock treatment 124400.0 2930.0 0.27 127600.0 3200.0 0.3 0.4001 0.9988 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O12 mock treatment 123600.0 2130.0 0.2 124800.0 400.0 0.04 0.1645 0.8264 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O13 compound treatment 119600.0 -1870.0 -0.17 114400.0 -10000.0 -0.93 -0.7773 -0.8244 3011925 CMLD2_000888 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/[C@@H](C)[C@H](OCc3ccccc3)C(C)C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O14 compound treatment 121200.0 -273.0 -0.03 122400.0 -2000.0 -0.19 -0.1489 -0.7958 3130636 CMLD2_000889 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O15 compound treatment 97200.0 -24300.0 -2.23 102400.0 -22000.0 -2.04 -3.0207 -0.999 3011927 CMLD2_000890 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O16 compound treatment 118000.0 -3470.0 -0.32 117200.0 -7200.0 -0.67 -0.6978 -0.9431 3130637 CMLD2_000891 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@@H]6COC[C@H]6O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O17 compound treatment 126000.0 4530.0 0.42 134800.0 10400.0 0.96 0.9761 0.9295 3130638 CMLD2_000892 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@@H]2COC[C@H]2O)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O18 compound treatment 119200.0 -2270.0 -0.21 128800.0 4400.0 0.41 0.1405 0.3066 3011928 CMLD2_000893 C[C@@H](ON=C(C)C)c1cn(nn1)[C@@H]2COC[C@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O19 compound treatment 126800.0 5330.0 0.49 129200.0 4800.0 0.44 0.6611 0.9988 3130639 CMLD2_000894 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O20 compound treatment 127200.0 5730.0 0.53 130400.0 6000.0 0.56 0.7657 0.9996 3011929 CMLD2_000895 CCN1C(=C([C@H](N2C(=O)[C@@](O)(CC(=C12)C(=O)C)C(=O)OC)c3ccccc3)C(=O)OC)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O21 compound treatment 118800.0 -2670.0 -0.25 123200.0 -1200.0 -0.11 -0.2525 -0.9357 3130640 CMLD2_000896 C[C@@H]1CC[C@@H]2N(C[C@@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O22 mock treatment 128400.0 6930.0 0.64 146000.0 21600.0 2.0 1.8662 0.8882 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O23 mock treatment 135600.0 14100.0 1.3 144400.0 20000.0 1.85 2.2297 0.9849 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 O24 mock treatment 126800.0 5330.0 0.49 130400.0 6000.0 0.56 0.7397 0.998 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P01 compound treatment 118800.0 -2670.0 -0.25 122400.0 -2000.0 -0.19 -0.305 -0.9903 3011930 CMLD2_000897 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P02 compound treatment 128400.0 6930.0 0.64 134000.0 9600.0 0.89 1.0797 0.9866 3130641 CMLD2_000898 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P03 compound treatment 106000.0 -15500.0 -1.42 111600.0 -12800.0 -1.19 -1.8454 -0.9959 3130642 CMLD2_000899 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)c4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P04 compound treatment 117600.0 -3870.0 -0.36 112400.0 -12000.0 -1.11 -1.0384 -0.8891 3130643 CMLD2_000900 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@@H]5COC[C@H]5O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P05 compound treatment 124800.0 3330.0 0.31 124800.0 400.0 0.04 0.2426 0.787 3011932 CMLD2_000901 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@@H]3COC[C@H]3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P06 compound treatment 125200.0 3730.0 0.34 130000.0 5600.0 0.52 0.6094 0.9797 3130644 CMLD2_000902 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P07 compound treatment 126800.0 5330.0 0.49 130400.0 6000.0 0.56 0.7397 0.998 3011933 CMLD2_000903 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P08 compound treatment 127200.0 5730.0 0.53 128800.0 4400.0 0.41 0.6609 0.992 3130645 CMLD2_000904 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)cc2)c4ccc(C)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P09 compound treatment 124800.0 3330.0 0.31 120800.0 -3600.0 -0.33 -0.0196 -0.0433 3011935 CMLD2_000905 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P10 compound treatment 118800.0 -2670.0 -0.25 126000.0 1600.0 0.15 -0.069 -0.2403 3130646 CMLD2_000906 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)COCc4ccco4)/[C@@H]2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P11 mock treatment 129600.0 8130.0 0.75 133200.0 8800.0 0.82 1.1053 0.9991 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P12 mock treatment 126400.0 4930.0 0.45 131600.0 7200.0 0.67 0.7923 0.9822 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P13 compound treatment 101600.0 -19900.0 -1.83 99600.0 -24800.0 -2.3 -2.9181 -0.9936 3130647 CMLD2_000907 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C)C=C[C@@H]1Oc3ccc(OC)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P14 compound treatment 112400.0 -9070.0 -0.83 111200.0 -13200.0 -1.22 -1.4553 -0.9826 3011936 CMLD2_000908 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P15 compound treatment 110400.0 -11100.0 -1.02 115600.0 -8800.0 -0.82 -1.297 -0.9939 3130648 CMLD2_000909 CCc1cc2CN(CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)CCc2nc1CC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P16 compound treatment 104800.0 -16700.0 -1.53 106400.0 -18000.0 -1.67 -2.2642 -0.9991 3130649 CMLD2_000910 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P17 compound treatment 122400.0 927.0 0.09 123200.0 -1200.0 -0.11 -0.0184 -0.1312 3011937 CMLD2_000911 CO[C@H](/C=N/O[C@@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P18 compound treatment 126400.0 4930.0 0.45 132800.0 8400.0 0.78 0.871 0.9668 3130650 CMLD2_000912 C[C@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P19 compound treatment 125200.0 3730.0 0.34 116400.0 -8000.0 -0.74 -0.282 -0.3451 3011939 CMLD2_000913 CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P20 compound treatment 136000.0 14500.0 1.34 127200.0 2800.0 0.26 1.1284 0.829 3131985 CMLD2_000914 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P21 compound treatment 122000.0 527.0 0.05 120400.0 -4000.0 -0.37 -0.2279 -0.6096 3130651 CMLD2_000915 C[C@@H]1CC[C@@H]2N(C[C@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P22 mock treatment 123200.0 1730.0 0.16 129600.0 5200.0 0.48 0.4531 0.8929 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P23 mock treatment 128800.0 7330.0 0.67 136400.0 12000.0 1.11 1.263 0.9712 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2111 P24 mock treatment 116400.0 -5070.0 -0.47 118800.0 -5600.0 -0.52 -0.697 -0.9986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A01 compound treatment 105200.0 -22800.0 -2.1 110800.0 -12400.0 -1.15 -2.2969 -0.9604 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A02 compound treatment 128000.0 22.7 0.0 121200.0 -2040.0 -0.19 -0.1323 -0.6992 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A03 compound treatment 125600.0 -2380.0 -0.22 122800.0 -441.0 -0.04 -0.1835 -0.825 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A04 compound treatment 134000.0 6020.0 0.55 125600.0 2360.0 0.22 0.5464 0.9173 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A05 compound treatment 120400.0 -7580.0 -0.7 110000.0 -13200.0 -1.23 -1.3607 -0.9641 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A06 compound treatment 142800.0 14800.0 1.36 148400.0 25200.0 2.33 2.6131 0.9673 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A07 compound treatment 132400.0 4420.0 0.41 123200.0 -40.9 0.0 0.285 0.7005 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A08 compound treatment 154800.0 26800.0 2.47 142000.0 18800.0 1.74 2.9741 0.9853 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A09 compound treatment 129200.0 1220.0 0.11 121600.0 -1640.0 -0.15 -0.028 -0.1481 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A10 compound treatment 129600.0 1620.0 0.15 117600.0 -5640.0 -0.52 -0.2642 -0.4858 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A11 compound treatment 119200.0 -8780.0 -0.81 109200.0 -14000.0 -1.3 -1.4912 -0.9736 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A12 compound treatment 143200.0 15200.0 1.4 136000.0 12800.0 1.18 1.8264 0.9965 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A13 mock treatment 124400.0 -3580.0 -0.33 115600.0 -7640.0 -0.71 -0.7335 -0.9392 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A14 mock treatment 126800.0 -1180.0 -0.11 122400.0 -841.0 -0.08 -0.1317 -0.987 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A15 compound treatment 127200.0 -777.0 -0.07 130400.0 7160.0 0.66 0.4187 0.6273 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A16 compound treatment 120800.0 -7180.0 -0.66 128000.0 4760.0 0.44 -0.1549 -0.1951 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A17 compound treatment 124000.0 -3980.0 -0.37 122000.0 -1240.0 -0.12 -0.34 -0.8866 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A18 compound treatment 126400.0 -1580.0 -0.15 116000.0 -7240.0 -0.67 -0.5772 -0.8405 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A19 compound treatment 131200.0 3220.0 0.3 123200.0 -40.9 0.0 0.2069 0.698 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A20 compound treatment 111200.0 -16800.0 -1.54 112800.0 -10400.0 -0.97 -1.7756 -0.9747 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A21 compound treatment 127200.0 -777.0 -0.07 122800.0 -441.0 -0.04 -0.0795 -0.9648 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A22 compound treatment 129600.0 1620.0 0.15 115200.0 -8040.0 -0.75 -0.4215 -0.5545 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A23 compound treatment 111200.0 -16800.0 -1.54 115600.0 -7640.0 -0.71 -1.592 -0.9376 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 A24 compound treatment 124000.0 -3980.0 -0.37 113200.0 -10000.0 -0.93 -0.9168 -0.9168 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B01 compound treatment 126400.0 -1580.0 -0.15 134400.0 11200.0 1.03 0.6288 0.602 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B02 compound treatment 124800.0 -3180.0 -0.29 112000.0 -11200.0 -1.04 -0.9434 -0.8718 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B03 compound treatment 147200.0 19200.0 1.77 140800.0 17600.0 1.63 2.4012 0.9991 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B04 compound treatment 114800.0 -13200.0 -1.21 113200.0 -10000.0 -0.93 -1.5152 -0.9915 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B05 compound treatment 124400.0 -3580.0 -0.33 128400.0 5160.0 0.48 0.1055 0.1817 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B06 compound treatment 135200.0 7220.0 0.66 126000.0 2760.0 0.26 0.6506 0.9139 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B07 compound treatment 149200.0 21200.0 1.95 134000.0 10800.0 1.0 2.0856 0.9514 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B08 compound treatment 137200.0 9220.0 0.85 122400.0 -841.0 -0.08 0.5448 0.6394 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B09 compound treatment 184400.0 56400.0 5.19 172800.0 49600.0 4.59 6.9181 0.9981 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B10 compound treatment 120400.0 -7580.0 -0.7 102400.0 -20800.0 -1.93 -1.8588 -0.9051 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B11 compound treatment 174400.0 46400.0 4.27 176400.0 53200.0 4.93 6.5036 0.9975 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B12 compound treatment 111200.0 -16800.0 -1.54 110000.0 -13200.0 -1.23 -1.9591 -0.9936 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B13 mock treatment 133200.0 5220.0 0.48 126000.0 2760.0 0.26 0.5205 0.9564 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B14 mock treatment 125600.0 -2380.0 -0.22 127200.0 3960.0 0.37 0.1049 0.2455 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B15 compound treatment 132800.0 4820.0 0.44 123600.0 359.0 0.03 0.3372 0.758 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B16 compound treatment 131200.0 3220.0 0.3 121600.0 -1640.0 -0.15 0.1021 0.3063 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B17 compound treatment 136000.0 8020.0 0.74 132800.0 9560.0 0.89 1.1483 0.9959 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B18 compound treatment 129200.0 1220.0 0.11 116000.0 -7240.0 -0.67 -0.3951 -0.5805 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B19 compound treatment 144400.0 16400.0 1.51 146400.0 23200.0 2.15 2.5861 0.9852 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B20 compound treatment 137600.0 9620.0 0.89 122800.0 -441.0 -0.04 0.597 0.6737 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B21 compound treatment 128800.0 823.0 0.08 134400.0 11200.0 1.03 0.7849 0.7568 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B22 compound treatment 125200.0 -2780.0 -0.26 118800.0 -4440.0 -0.41 -0.4717 -0.9737 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B23 compound treatment 143600.0 15600.0 1.44 144000.0 20800.0 1.92 2.3767 0.9897 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 B24 compound treatment 132400.0 4420.0 0.41 114400.0 -8840.0 -0.82 -0.2918 -0.3189 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C01 compound treatment 96400.0 -31600.0 -2.9 85200.0 -38000.0 -3.53 -4.5471 -0.9954 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C02 compound treatment 137200.0 9220.0 0.85 125600.0 2360.0 0.22 0.7545 0.8612 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C03 compound treatment 126800.0 -1180.0 -0.11 118800.0 -4440.0 -0.41 -0.3676 -0.8637 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C04 compound treatment 154000.0 26000.0 2.39 150000.0 26800.0 2.48 3.4464 0.9998 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C05 compound treatment 133200.0 5220.0 0.48 126000.0 2760.0 0.26 0.5205 0.9564 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C06 compound treatment 156800.0 28800.0 2.65 151200.0 28000.0 2.59 3.7072 0.9999 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C07 compound treatment 132000.0 4020.0 0.37 118400.0 -4840.0 -0.45 -0.0556 -0.0957 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C08 compound treatment 156400.0 28400.0 2.61 148400.0 25200.0 2.33 3.4977 0.9984 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C09 compound treatment 125600.0 -2380.0 -0.22 126800.0 3560.0 0.33 0.0786 0.1987 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C10 compound treatment 137600.0 9620.0 0.89 132800.0 9560.0 0.89 1.2524 1.0 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C11 mock treatment 124400.0 -3580.0 -0.33 119600.0 -3640.0 -0.34 -0.4713 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C12 mock treatment 128000.0 22.7 0.0 118400.0 -4840.0 -0.45 -0.3158 -0.7038 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C13 compound treatment 123600.0 -4380.0 -0.4 111600.0 -11600.0 -1.08 -1.0477 -0.9097 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C14 compound treatment 113600.0 -14400.0 -1.32 110000.0 -13200.0 -1.23 -1.803 -0.9993 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C15 mock treatment 124400.0 -3580.0 -0.33 120400.0 -2840.0 -0.26 -0.4189 -0.9939 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C16 mock treatment 128400.0 423.0 0.04 122800.0 -441.0 -0.04 -0.0014 -0.0249 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C17 compound treatment 129200.0 1220.0 0.11 122800.0 -441.0 -0.04 0.0506 0.4231 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C18 compound treatment 116800.0 -11200.0 -1.03 103600.0 -19600.0 -1.82 -2.0143 -0.9634 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C19 compound treatment 137600.0 9620.0 0.89 133200.0 9960.0 0.92 1.2786 0.9998 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C20 compound treatment 128800.0 823.0 0.08 122000.0 -1240.0 -0.12 -0.0278 -0.2021 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C21 compound treatment 123600.0 -4380.0 -0.4 113600.0 -9640.0 -0.89 -0.9166 -0.9352 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C22 compound treatment 132800.0 4820.0 0.44 130000.0 6760.0 0.63 0.7567 0.9857 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C23 compound treatment 132000.0 4020.0 0.37 130800.0 7560.0 0.7 0.7571 0.9555 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 C24 compound treatment 140800.0 12800.0 1.18 142400.0 19200.0 1.78 2.0897 0.9802 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D01 compound treatment 139600.0 11600.0 1.07 123200.0 -40.9 0.0 0.7533 0.7046 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D02 compound treatment 110000.0 -18000.0 -1.65 95200.0 -28000.0 -2.6 -3.0071 -0.9762 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D03 compound treatment 167200.0 39200.0 3.61 159200.0 36000.0 3.33 4.908 0.9992 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D04 compound treatment 126000.0 -1980.0 -0.18 115600.0 -7640.0 -0.71 -0.6294 -0.8608 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D05 compound treatment 135600.0 7620.0 0.7 124400.0 1160.0 0.11 0.5718 0.806 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D06 compound treatment 86400.0 -41600.0 -3.82 86800.0 -36400.0 -3.38 -5.0927 -0.9981 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D07 compound treatment 132800.0 4820.0 0.44 131600.0 8360.0 0.77 0.8616 0.965 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D08 compound treatment 119600.0 -8380.0 -0.77 115600.0 -7640.0 -0.71 -1.0457 -0.9991 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D09 compound treatment 169200.0 41200.0 3.79 173200.0 50000.0 4.63 5.9556 0.9951 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D10 compound treatment 117600.0 -10400.0 -0.95 125600.0 2360.0 0.22 -0.5203 -0.5314 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D11 mock treatment 122400.0 -5580.0 -0.51 118000.0 -5240.0 -0.49 -0.7063 -0.9996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D12 mock treatment 130000.0 2020.0 0.19 122800.0 -441.0 -0.04 0.1027 0.5389 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D13 compound treatment 118400.0 -9580.0 -0.88 122000.0 -1240.0 -0.12 -0.7043 -0.7927 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D14 compound treatment 112800.0 -15200.0 -1.4 112800.0 -10400.0 -0.97 -1.6715 -0.984 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D15 mock treatment 123200.0 -4780.0 -0.44 125600.0 2360.0 0.22 -0.1561 -0.318 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D16 mock treatment 135600.0 7620.0 0.7 116000.0 -7240.0 -0.67 0.0212 0.0219 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D17 compound treatment 132800.0 4820.0 0.44 134400.0 11200.0 1.03 1.0451 0.9286 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D18 compound treatment 123600.0 -4380.0 -0.4 125200.0 1960.0 0.18 -0.1563 -0.3539 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D19 compound treatment 166000.0 38000.0 3.5 164000.0 40800.0 3.78 5.1445 0.9993 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D20 compound treatment 124800.0 -3180.0 -0.29 105600.0 -17600.0 -1.64 -1.3629 -0.8205 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D21 compound treatment 131200.0 3220.0 0.3 140400.0 17200.0 1.59 1.3343 0.8247 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D22 compound treatment 123600.0 -4380.0 -0.4 129200.0 5960.0 0.55 0.1059 0.1549 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D23 compound treatment 137200.0 9220.0 0.85 134400.0 11200.0 1.03 1.3313 0.9952 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 D24 compound treatment 124800.0 -3180.0 -0.29 123200.0 -40.9 0.0 -0.2093 -0.7162 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E01 mock treatment 126400.0 -1580.0 -0.15 122800.0 -441.0 -0.04 -0.1315 -0.8723 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E02 mock treatment 130400.0 2420.0 0.22 122400.0 -841.0 -0.08 0.1025 0.434 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E03 compound treatment 120000.0 -7980.0 -0.73 112800.0 -10400.0 -0.97 -1.2032 -0.9907 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E04 compound treatment 118800.0 -9180.0 -0.84 117200.0 -6040.0 -0.56 -0.9928 -0.9801 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E05 compound treatment 144800.0 16800.0 1.55 132800.0 9560.0 0.89 1.7207 0.965 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E06 compound treatment 142800.0 14800.0 1.36 126800.0 3560.0 0.33 1.1974 0.8536 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E07 compound treatment 126000.0 -1980.0 -0.18 118800.0 -4440.0 -0.41 -0.4197 -0.9326 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E08 compound treatment 136000.0 8020.0 0.74 134000.0 10800.0 1.0 1.227 0.989 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E09 mock treatment 120000.0 -7980.0 -0.73 120800.0 -2440.0 -0.23 -0.6788 -0.8841 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E10 mock treatment 121600.0 -6380.0 -0.59 118400.0 -4840.0 -0.45 -0.7321 -0.9912 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E11 compound treatment 126800.0 -1180.0 -0.11 116800.0 -6440.0 -0.6 -0.4987 -0.822 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E12 compound treatment 122800.0 -5180.0 -0.48 121600.0 -1640.0 -0.15 -0.4443 -0.8887 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E13 compound treatment 135600.0 7620.0 0.7 123200.0 -40.9 0.0 0.4931 0.7033 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E14 compound treatment 124400.0 -3580.0 -0.33 122400.0 -841.0 -0.08 -0.2878 -0.8511 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E15 compound treatment 125600.0 -2380.0 -0.22 114000.0 -9240.0 -0.86 -0.7603 -0.86 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E16 compound treatment 140400.0 12400.0 1.14 106800.0 -16400.0 -1.52 -0.2696 -0.1415 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E17 mock treatment 120800.0 -7180.0 -0.66 119600.0 -3640.0 -0.34 -0.7055 -0.9515 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E18 mock treatment 122400.0 -5580.0 -0.51 122800.0 -441.0 -0.04 -0.3917 -0.761 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E19 compound treatment 126400.0 -1580.0 -0.15 124400.0 1160.0 0.11 -0.0266 -0.1475 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E20 compound treatment 146000.0 18000.0 1.66 146000.0 22800.0 2.11 2.6639 0.9929 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E21 compound treatment 122400.0 -5580.0 -0.51 127600.0 4360.0 0.4 -0.0771 -0.118 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E22 compound treatment 133600.0 5620.0 0.52 123600.0 359.0 0.03 0.3893 0.7511 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E23 compound treatment 134000.0 6020.0 0.55 130000.0 6760.0 0.63 0.8347 0.9981 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 E24 compound treatment 130800.0 2820.0 0.26 127600.0 4360.0 0.4 0.4693 0.9771 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F01 mock treatment 119600.0 -8380.0 -0.77 121600.0 -1640.0 -0.15 -0.6524 -0.8306 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F02 mock treatment 124000.0 -3980.0 -0.37 111200.0 -12000.0 -1.12 -1.0479 -0.8922 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F03 compound treatment 132400.0 4420.0 0.41 123600.0 359.0 0.03 0.3112 0.7624 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F04 compound treatment 88000.0 -40000.0 -3.68 89200.0 -34000.0 -3.16 -4.8313 -0.9971 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F05 compound treatment 124800.0 -3180.0 -0.29 113200.0 -10000.0 -0.93 -0.8648 -0.8865 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F06 compound treatment 121200.0 -6780.0 -0.62 107200.0 -16000.0 -1.49 -1.4922 -0.9255 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F07 compound treatment 119200.0 -8780.0 -0.81 116400.0 -6840.0 -0.63 -1.0193 -0.9929 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F08 compound treatment 104000.0 -24000.0 -2.21 104400.0 -18800.0 -1.75 -2.7944 -0.9933 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F09 mock treatment 118800.0 -9180.0 -0.84 119600.0 -3640.0 -0.34 -0.8355 -0.9191 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F10 mock treatment 122800.0 -5180.0 -0.48 117200.0 -6040.0 -0.56 -0.7327 -0.9968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F11 compound treatment 170000.0 42000.0 3.87 181200.0 58000.0 5.37 6.532 0.987 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F12 compound treatment 115600.0 -12400.0 -1.14 112000.0 -11200.0 -1.04 -1.5418 -0.999 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F13 compound treatment 122800.0 -5180.0 -0.48 116400.0 -6840.0 -0.63 -0.7851 -0.99 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F14 compound treatment 106400.0 -21600.0 -1.98 86400.0 -36800.0 -3.41 -3.8181 -0.9667 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F15 compound treatment 123200.0 -4780.0 -0.44 110400.0 -12800.0 -1.19 -1.1523 -0.9082 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F16 compound treatment 72800.0 -55200.0 -5.08 70400.0 -52800.0 -4.9 -7.0522 -0.9998 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F17 mock treatment 124000.0 -3980.0 -0.37 117200.0 -6040.0 -0.56 -0.6546 -0.9787 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F18 mock treatment 116800.0 -11200.0 -1.03 114800.0 -8440.0 -0.78 -1.2802 -0.9909 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F19 compound treatment 144400.0 16400.0 1.51 144800.0 21600.0 2.0 2.4812 0.9905 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F20 compound treatment 112400.0 -15600.0 -1.43 110000.0 -13200.0 -1.23 -1.881 -0.997 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F21 compound treatment 127200.0 -777.0 -0.07 135200.0 12000.0 1.11 0.7333 0.6601 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F22 compound treatment 118400.0 -9580.0 -0.88 119600.0 -3640.0 -0.34 -0.8616 -0.9133 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F23 compound treatment 131200.0 3220.0 0.3 127200.0 3960.0 0.37 0.4691 0.9944 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 F24 compound treatment 117600.0 -10400.0 -0.95 115600.0 -7640.0 -0.71 -1.1758 -0.9892 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G01 compound treatment 135200.0 7220.0 0.66 134800.0 11600.0 1.07 1.2274 0.9736 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G02 compound treatment 94400.0 -33600.0 -3.09 88800.0 -34400.0 -3.19 -4.4413 -0.9999 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G03 mock treatment 124800.0 -3180.0 -0.29 114800.0 -8440.0 -0.78 -0.7599 -0.9098 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G04 mock treatment 120400.0 -7580.0 -0.7 123200.0 -40.9 0.0 -0.4955 -0.7109 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G05 compound treatment 121600.0 -6380.0 -0.59 124000.0 759.0 0.07 -0.365 -0.6179 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G06 compound treatment 128800.0 823.0 0.08 134800.0 11600.0 1.07 0.8111 0.7552 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G07 compound treatment 118400.0 -9580.0 -0.88 112800.0 -10400.0 -0.97 -1.3072 -0.9989 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G08 compound treatment 150400.0 22400.0 2.06 142000.0 18800.0 1.74 2.6879 0.9964 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G09 compound treatment 117600.0 -10400.0 -0.95 114000.0 -9240.0 -0.86 -1.2806 -0.9985 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G10 compound treatment 136000.0 8020.0 0.74 131600.0 8360.0 0.77 1.0697 0.9997 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G11 compound treatment 124000.0 -3980.0 -0.37 113600.0 -9640.0 -0.89 -0.8906 -0.9223 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G12 compound treatment 126400.0 -1580.0 -0.15 104000.0 -19200.0 -1.78 -1.3637 -0.7621 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G13 compound treatment 126400.0 -1580.0 -0.15 116400.0 -6840.0 -0.63 -0.551 -0.847 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G14 compound treatment 125200.0 -2780.0 -0.26 122000.0 -1240.0 -0.12 -0.262 -0.9351 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G15 compound treatment 130800.0 2820.0 0.26 122000.0 -1240.0 -0.12 0.1023 0.3601 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G16 compound treatment 143200.0 15200.0 1.4 134000.0 10800.0 1.0 1.6953 0.9862 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G17 compound treatment 138000.0 10000.0 0.92 129200.0 5960.0 0.55 1.0425 0.97 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G18 compound treatment 132400.0 4420.0 0.41 116800.0 -6440.0 -0.6 -0.1345 -0.1862 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G19 mock treatment 129600.0 1620.0 0.15 121200.0 -2040.0 -0.19 -0.0282 -0.1171 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G20 mock treatment 130000.0 2020.0 0.19 121200.0 -2040.0 -0.19 -0.0022 -0.0083 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G21 compound treatment 135200.0 7220.0 0.66 128800.0 5560.0 0.52 0.8341 0.9921 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G22 compound treatment 137200.0 9220.0 0.85 135600.0 12400.0 1.15 1.4099 0.9891 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G23 compound treatment 127600.0 -377.0 -0.03 131600.0 8360.0 0.77 0.5233 0.6748 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 G24 compound treatment 137600.0 9620.0 0.89 123200.0 -40.9 0.0 0.6232 0.7041 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H01 compound treatment 125600.0 -2380.0 -0.22 119600.0 -3640.0 -0.34 -0.3933 -0.9779 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H02 compound treatment 128800.0 823.0 0.08 125200.0 1960.0 0.18 0.1819 0.9247 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H03 mock treatment 127200.0 -777.0 -0.07 125600.0 2360.0 0.22 0.1041 0.4523 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H04 mock treatment 127600.0 -377.0 -0.03 124400.0 1160.0 0.11 0.0514 0.4555 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H05 compound treatment 136400.0 8420.0 0.77 126800.0 3560.0 0.33 0.7811 0.9276 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H06 compound treatment 102000.0 -26000.0 -2.39 96800.0 -26400.0 -2.45 -3.4226 -0.9999 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H07 compound treatment 120800.0 -7180.0 -0.66 114800.0 -8440.0 -0.78 -1.0201 -0.9964 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H08 compound treatment 128400.0 423.0 0.04 114800.0 -8440.0 -0.78 -0.5257 -0.6711 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H09 compound treatment 160400.0 32400.0 2.98 156000.0 32800.0 3.04 4.256 1.0 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H10 compound treatment 116400.0 -11600.0 -1.06 95600.0 -27600.0 -2.56 -2.5647 -0.9243 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H11 compound treatment 149600.0 21600.0 1.99 146800.0 23600.0 2.18 2.9505 0.9989 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H12 compound treatment 121600.0 -6380.0 -0.59 112000.0 -11200.0 -1.04 -1.1515 -0.9631 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H13 compound treatment 112400.0 -15600.0 -1.43 110400.0 -12800.0 -1.19 -1.8548 -0.9957 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H14 compound treatment 76400.0 -51600.0 -4.74 70000.0 -53200.0 -4.93 -6.8442 -0.9998 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H15 compound treatment 127600.0 -377.0 -0.03 114400.0 -8840.0 -0.82 -0.604 -0.7364 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H16 compound treatment 108400.0 -19600.0 -1.8 104400.0 -18800.0 -1.75 -2.5082 -0.9999 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H17 compound treatment 135600.0 7620.0 0.7 136400.0 13200.0 1.22 1.3583 0.9654 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H18 compound treatment 109600.0 -18400.0 -1.69 104800.0 -18400.0 -1.71 -2.404 -1.0 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H19 mock treatment 128000.0 22.7 0.0 122400.0 -841.0 -0.08 -0.0536 -0.6879 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H20 mock treatment 118800.0 -9180.0 -0.84 122800.0 -441.0 -0.04 -0.6258 -0.7405 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H21 compound treatment 162800.0 34800.0 3.2 155600.0 32400.0 3.0 4.3858 0.9995 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H22 compound treatment 75200.0 -52800.0 -4.85 81200.0 -42000.0 -3.9 -6.1882 -0.9941 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H23 compound treatment 142000.0 14000.0 1.29 127600.0 4360.0 0.4 1.1978 0.8861 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 H24 compound treatment 109200.0 -18800.0 -1.73 119200.0 -4040.0 -0.37 -1.4862 -0.8409 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I01 compound treatment 125600.0 -2380.0 -0.22 116000.0 -7240.0 -0.67 -0.6292 -0.8914 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I02 compound treatment 135200.0 7220.0 0.66 123200.0 -40.9 0.0 0.4671 0.7031 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I03 compound treatment 126000.0 -1980.0 -0.18 125200.0 1960.0 0.18 -2.0E-4 -8.0E-4 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I04 compound treatment 131200.0 3220.0 0.3 118400.0 -4840.0 -0.45 -0.1077 -0.2002 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I05 mock treatment 123600.0 -4380.0 -0.4 122800.0 -441.0 -0.04 -0.3136 -0.7749 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I06 mock treatment 128400.0 423.0 0.04 115200.0 -8040.0 -0.75 -0.4995 -0.6693 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I07 compound treatment 116000.0 -12000.0 -1.1 117200.0 -6040.0 -0.56 -1.175 -0.9507 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I08 compound treatment 122000.0 -5980.0 -0.55 108800.0 -14400.0 -1.34 -1.3353 -0.9227 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I09 compound treatment 124400.0 -3580.0 -0.33 118400.0 -4840.0 -0.45 -0.55 -0.9884 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I10 compound treatment 120800.0 -7180.0 -0.66 116400.0 -6840.0 -0.63 -0.9152 -0.9998 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I11 compound treatment 120800.0 -7180.0 -0.66 116000.0 -7240.0 -0.67 -0.9414 -1.0 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I12 compound treatment 124800.0 -3180.0 -0.29 114400.0 -8840.0 -0.82 -0.7861 -0.9035 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I13 compound treatment 121600.0 -6380.0 -0.59 116800.0 -6440.0 -0.6 -0.8369 -1.0 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I14 compound treatment 127600.0 -377.0 -0.03 116800.0 -6440.0 -0.6 -0.4467 -0.7469 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I15 compound treatment 131600.0 3620.0 0.33 126000.0 2760.0 0.26 0.4165 0.9915 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I16 compound treatment 128000.0 22.7 0.0 122000.0 -1240.0 -0.12 -0.0799 -0.6941 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I17 compound treatment 122000.0 -5980.0 -0.55 122400.0 -841.0 -0.08 -0.4439 -0.7994 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I18 compound treatment 121600.0 -6380.0 -0.59 109200.0 -14000.0 -1.3 -1.3351 -0.9352 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I19 compound treatment 122000.0 -5980.0 -0.55 114400.0 -8840.0 -0.82 -0.9682 -0.9812 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I20 compound treatment 167200.0 39200.0 3.61 170800.0 47600.0 4.41 5.6683 0.9951 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I21 mock treatment 125600.0 -2380.0 -0.22 132000.0 8760.0 0.81 0.4195 0.4989 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I22 mock treatment 132000.0 4020.0 0.37 129600.0 6360.0 0.59 0.6784 0.9748 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I23 compound treatment 130000.0 2020.0 0.19 125600.0 2360.0 0.22 0.2862 0.9968 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 I24 compound treatment 145200.0 17200.0 1.58 154400.0 31200.0 2.89 3.1624 0.96 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J01 compound treatment 121200.0 -6780.0 -0.62 124000.0 759.0 0.07 -0.3911 -0.6233 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J02 compound treatment 110000.0 -18000.0 -1.65 90800.0 -32400.0 -3.01 -3.2955 -0.9603 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J03 compound treatment 125200.0 -2780.0 -0.26 127200.0 3960.0 0.37 0.0788 0.1763 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J04 compound treatment 131600.0 3620.0 0.33 124800.0 1560.0 0.14 0.3378 0.9301 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J05 mock treatment 119600.0 -8380.0 -0.77 120400.0 -2840.0 -0.26 -0.7311 -0.8978 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J06 mock treatment 126400.0 -1580.0 -0.15 114000.0 -9240.0 -0.86 -0.7083 -0.8153 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J07 compound treatment 123600.0 -4380.0 -0.4 127200.0 3960.0 0.37 -0.0252 -0.0463 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J08 compound treatment 117600.0 -10400.0 -0.95 108000.0 -15200.0 -1.41 -1.6739 -0.9818 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J09 compound treatment 170400.0 42400.0 3.9 176800.0 53600.0 4.96 6.2697 0.9929 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J10 compound treatment 120000.0 -7980.0 -0.73 116000.0 -7240.0 -0.67 -0.9934 -0.999 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J11 compound treatment 182800.0 54800.0 5.04 172000.0 48800.0 4.52 6.7616 0.9985 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J12 compound treatment 132000.0 4020.0 0.37 124000.0 759.0 0.07 0.3114 0.8267 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J13 compound treatment 124800.0 -3180.0 -0.29 117200.0 -6040.0 -0.56 -0.6026 -0.954 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J14 compound treatment 96400.0 -31600.0 -2.9 91200.0 -32000.0 -2.97 -4.1539 -0.9999 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J15 compound treatment 121200.0 -6780.0 -0.62 129200.0 5960.0 0.55 -0.0502 -0.0603 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J16 compound treatment 78400.0 -49600.0 -4.56 66800.0 -56400.0 -5.23 -6.9239 -0.9977 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J17 compound treatment 166000.0 38000.0 3.5 181600.0 58400.0 5.41 6.2981 0.9777 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J18 compound treatment 94400.0 -33600.0 -3.09 89600.0 -33600.0 -3.12 -4.3888 -1.0 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J19 compound treatment 142400.0 14400.0 1.33 141200.0 18000.0 1.66 2.1152 0.9937 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J20 compound treatment 117200.0 -10800.0 -0.99 117600.0 -5640.0 -0.52 -1.0707 -0.9553 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J21 mock treatment 128000.0 22.7 0.0 128000.0 4760.0 0.44 0.3134 0.7104 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J22 mock treatment 134800.0 6820.0 0.63 136400.0 13200.0 1.22 1.3062 0.9523 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J23 compound treatment 138800.0 10800.0 1.0 127600.0 4360.0 0.4 0.9896 0.9211 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 J24 compound treatment 114800.0 -13200.0 -1.21 105200.0 -18000.0 -1.67 -2.0395 -0.9875 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K01 compound treatment 119200.0 -8780.0 -0.81 109600.0 -13600.0 -1.26 -1.4649 -0.9765 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K02 compound treatment 136000.0 8020.0 0.74 131600.0 8360.0 0.77 1.0697 0.9997 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K03 compound treatment 52400.0 -75600.0 -6.95 69200.0 -54000.0 -5.01 -8.4577 -0.9871 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K04 compound treatment 131200.0 3220.0 0.3 112400.0 -10800.0 -1.0 -0.5009 -0.4781 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K05 compound treatment 110400.0 -17600.0 -1.62 94000.0 -29200.0 -2.71 -3.0598 -0.9695 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K06 compound treatment 155200.0 27200.0 2.5 145200.0 22000.0 2.04 3.2099 0.9947 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K07 mock treatment 122000.0 -5980.0 -0.55 118000.0 -5240.0 -0.49 -0.7323 -0.9981 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K08 mock treatment 120000.0 -7980.0 -0.73 114000.0 -9240.0 -0.86 -1.1245 -0.997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K09 compound treatment 92000.0 -36000.0 -3.31 78800.0 -44400.0 -4.12 -5.2528 -0.9941 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K10 compound treatment 120800.0 -7180.0 -0.66 98800.0 -24400.0 -2.27 -2.0687 -0.8767 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K11 compound treatment 96000.0 -32000.0 -2.94 86800.0 -36400.0 -3.38 -4.4683 -0.9976 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K12 compound treatment 116000.0 -12000.0 -1.1 106400.0 -16800.0 -1.56 -1.8828 -0.9854 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K13 compound treatment 120400.0 -7580.0 -0.7 112000.0 -11200.0 -1.04 -1.2296 -0.9809 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K14 compound treatment 120800.0 -7180.0 -0.66 118400.0 -4840.0 -0.45 -0.7841 -0.9823 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K15 mock treatment 124400.0 -3580.0 -0.33 124400.0 1160.0 0.11 -0.1567 -0.4527 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K16 mock treatment 122800.0 -5180.0 -0.48 120800.0 -2440.0 -0.23 -0.4967 -0.9421 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K17 compound treatment 110400.0 -17600.0 -1.62 101600.0 -21600.0 -2.01 -2.5617 -0.9943 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K18 compound treatment 125600.0 -2380.0 -0.22 128000.0 4760.0 0.44 0.1573 0.3195 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K19 compound treatment 111200.0 -16800.0 -1.54 112400.0 -10800.0 -1.0 -1.8018 -0.9784 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K20 compound treatment 124000.0 -3980.0 -0.37 125200.0 1960.0 0.18 -0.1303 -0.319 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K21 compound treatment 113600.0 -14400.0 -1.32 118400.0 -4840.0 -0.45 -1.2524 -0.8968 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K22 compound treatment 144400.0 16400.0 1.51 152000.0 28800.0 2.67 2.9531 0.9638 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K23 mock treatment 137200.0 9220.0 0.85 134000.0 10800.0 1.0 1.305 0.9968 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 K24 mock treatment 134800.0 6820.0 0.63 124800.0 1560.0 0.14 0.546 0.8477 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L01 compound treatment 146000.0 18000.0 1.66 141200.0 18000.0 1.66 2.3493 1.0 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L02 compound treatment 143600.0 15600.0 1.44 132400.0 9160.0 0.85 1.6164 0.9685 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L03 compound treatment 145200.0 17200.0 1.58 142000.0 18800.0 1.74 2.3497 0.9989 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L04 compound treatment 132000.0 4020.0 0.37 124400.0 1160.0 0.11 0.3376 0.8762 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L05 compound treatment 138400.0 10400.0 0.96 124400.0 1160.0 0.11 0.7539 0.7815 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L06 compound treatment 100000.0 -28000.0 -2.57 86800.0 -36400.0 -3.38 -4.2081 -0.991 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L07 mock treatment 127200.0 -777.0 -0.07 133600.0 10400.0 0.96 0.6284 0.6526 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L08 mock treatment 124000.0 -3980.0 -0.37 119600.0 -3640.0 -0.34 -0.4973 -0.9992 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L09 compound treatment 179600.0 51600.0 4.75 171600.0 48400.0 4.48 6.5272 0.9996 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L10 compound treatment 98000.0 -30000.0 -2.76 98400.0 -24800.0 -2.3 -3.5779 -0.996 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L11 compound treatment 168000.0 40000.0 3.68 181200.0 58000.0 5.37 6.4019 0.983 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L12 compound treatment 124400.0 -3580.0 -0.33 113200.0 -10000.0 -0.93 -0.8908 -0.9024 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L13 compound treatment 153200.0 25200.0 2.32 156800.0 33600.0 3.11 3.8401 0.9896 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L14 compound treatment 90400.0 -37600.0 -3.46 88400.0 -34800.0 -3.23 -4.7277 -0.9994 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L15 mock treatment 126800.0 -1180.0 -0.11 121600.0 -1640.0 -0.15 -0.1841 -0.9861 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L16 mock treatment 128000.0 22.7 0.0 120400.0 -2840.0 -0.26 -0.1847 -0.7015 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L17 compound treatment 156800.0 28800.0 2.65 136800.0 13600.0 1.26 2.7634 0.9418 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L18 compound treatment 103200.0 -24800.0 -2.28 97600.0 -25600.0 -2.38 -3.2921 -0.9998 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L19 compound treatment 154000.0 26000.0 2.39 152800.0 29600.0 2.74 3.6299 0.9977 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L20 compound treatment 84000.0 -44000.0 -4.05 80800.0 -42400.0 -3.93 -5.6421 -0.9999 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L21 compound treatment 126000.0 -1980.0 -0.18 124000.0 759.0 0.07 -0.0789 -0.4044 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L22 compound treatment 74000.0 -54000.0 -4.97 76800.0 -46400.0 -4.3 -6.5546 -0.9975 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L23 mock treatment 134000.0 6020.0 0.55 130400.0 7160.0 0.66 0.861 0.996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 L24 mock treatment 132800.0 4820.0 0.44 129200.0 5960.0 0.55 0.7043 0.9941 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M01 compound treatment 122000.0 -5980.0 -0.55 112800.0 -10400.0 -0.97 -1.0731 -0.9641 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M02 compound treatment 144000.0 16000.0 1.47 139200.0 16000.0 1.48 2.0881 1.0 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M03 compound treatment 123600.0 -4380.0 -0.4 120000.0 -3240.0 -0.3 -0.4971 -0.9896 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M04 compound treatment 146000.0 18000.0 1.66 144400.0 21200.0 1.96 2.5591 0.9965 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M05 compound treatment 127200.0 -777.0 -0.07 123200.0 -40.9 0.0 -0.0532 -0.7436 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M06 compound treatment 133600.0 5620.0 0.52 122000.0 -1240.0 -0.12 0.2844 0.5367 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M07 compound treatment 125200.0 -2780.0 -0.26 114800.0 -8440.0 -0.78 -0.7339 -0.8917 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M08 compound treatment 127200.0 -777.0 -0.07 120800.0 -2440.0 -0.23 -0.2105 -0.8873 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M09 mock treatment 122000.0 -5980.0 -0.55 108800.0 -14400.0 -1.34 -1.3353 -0.9227 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M10 mock treatment 119200.0 -8780.0 -0.81 112400.0 -10800.0 -1.0 -1.2814 -0.9941 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M11 compound treatment 126000.0 -1980.0 -0.18 116000.0 -7240.0 -0.67 -0.6032 -0.8674 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M12 compound treatment 120800.0 -7180.0 -0.66 120000.0 -3240.0 -0.3 -0.6792 -0.9365 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M13 mock treatment 121200.0 -6780.0 -0.62 117600.0 -5640.0 -0.52 -0.8105 -0.9962 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M14 mock treatment 130000.0 2020.0 0.19 121600.0 -1640.0 -0.15 0.024 0.0999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M15 compound treatment 118400.0 -9580.0 -0.88 118000.0 -5240.0 -0.49 -0.9664 -0.9607 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M16 compound treatment 124800.0 -3180.0 -0.29 124800.0 1560.0 0.14 -0.1045 -0.3204 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M17 compound treatment 133600.0 5620.0 0.52 117200.0 -6040.0 -0.56 -0.0302 -0.0396 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M18 compound treatment 140800.0 12800.0 1.18 141600.0 18400.0 1.7 2.0373 0.984 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M19 mock treatment 135200.0 7220.0 0.66 130400.0 7160.0 0.66 0.939 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M20 compound treatment 126400.0 -1580.0 -0.15 128000.0 4760.0 0.44 0.2093 0.4508 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M21 mock treatment 125600.0 -2380.0 -0.22 125600.0 2360.0 0.22 0.0 0.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M22 compound treatment 126800.0 -1180.0 -0.11 126000.0 2760.0 0.26 0.1043 0.3754 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M23 mock treatment 132400.0 4420.0 0.41 128800.0 5560.0 0.52 0.652 0.9932 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 M24 compound treatment 123200.0 -4780.0 -0.44 139600.0 16400.0 1.52 0.7615 0.4823 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N01 compound treatment 134000.0 6020.0 0.55 137200.0 14000.0 1.29 1.3066 0.9283 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N02 compound treatment 94400.0 -33600.0 -3.09 68400.0 -54800.0 -5.08 -5.7783 -0.9715 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N03 compound treatment 137200.0 9220.0 0.85 132800.0 9560.0 0.89 1.2264 0.9998 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N04 compound treatment 130000.0 2020.0 0.19 120400.0 -2840.0 -0.26 -0.0546 -0.1695 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N05 compound treatment 136800.0 8820.0 0.81 130800.0 7560.0 0.7 1.0693 0.9973 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N06 compound treatment 117200.0 -10800.0 -0.99 103600.0 -19600.0 -1.82 -1.9883 -0.9592 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N07 compound treatment 181600.0 53600.0 4.93 177600.0 54400.0 5.04 7.0506 0.9999 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N08 compound treatment 106000.0 -22000.0 -2.02 99600.0 -23600.0 -2.19 -2.9789 -0.9992 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N09 mock treatment 132000.0 4020.0 0.37 127600.0 4360.0 0.4 0.5474 0.999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N10 mock treatment 126800.0 -1180.0 -0.11 123200.0 -40.9 0.0 -0.0793 -0.7314 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N11 compound treatment 179600.0 51600.0 4.75 192800.0 69600.0 6.45 7.9167 0.9887 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N12 compound treatment 86800.0 -41200.0 -3.79 75200.0 -48000.0 -4.45 -5.827 -0.9968 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N13 mock treatment 134400.0 6420.0 0.59 111600.0 -11600.0 -1.08 -0.3452 -0.2806 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N14 mock treatment 128400.0 423.0 0.04 111600.0 -11600.0 -1.08 -0.7355 -0.6812 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N15 compound treatment 136800.0 8820.0 0.81 135200.0 12000.0 1.11 1.3577 0.9883 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N16 compound treatment 127200.0 -777.0 -0.07 119200.0 -4040.0 -0.37 -0.3154 -0.8271 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N17 compound treatment 130400.0 2420.0 0.22 135600.0 12400.0 1.15 0.9676 0.8291 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N18 compound treatment 82000.0 -46000.0 -4.23 92400.0 -30800.0 -2.86 -5.0119 -0.9818 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N19 compound treatment 154800.0 26800.0 2.47 153200.0 30000.0 2.78 3.7082 0.9983 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N20 compound treatment 86400.0 -41600.0 -3.82 83200.0 -40000.0 -3.71 -5.3287 -0.9999 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N21 compound treatment 140800.0 12800.0 1.18 129200.0 5960.0 0.55 1.2246 0.9402 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N22 compound treatment 98800.0 -29200.0 -2.68 97200.0 -26000.0 -2.41 -3.6045 -0.9986 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N23 compound treatment 140800.0 12800.0 1.18 132800.0 9560.0 0.89 1.4605 0.9901 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 N24 compound treatment 92800.0 -35200.0 -3.24 85200.0 -38000.0 -3.53 -4.7813 -0.9991 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O01 mock treatment 121600.0 -6380.0 -0.59 118000.0 -5240.0 -0.49 -0.7583 -0.9956 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O02 compound treatment 139200.0 11200.0 1.03 138800.0 15600.0 1.44 1.7497 0.9866 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O03 mock treatment 137200.0 9220.0 0.85 127600.0 4360.0 0.4 0.8856 0.9425 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O04 mock treatment 122400.0 -5580.0 -0.51 126800.0 3560.0 0.33 -0.1295 -0.2123 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O05 mock treatment 130000.0 2020.0 0.19 127600.0 4360.0 0.4 0.4173 0.938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O06 mock treatment 132800.0 4820.0 0.44 129200.0 5960.0 0.55 0.7043 0.9941 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O07 mock treatment 136400.0 8420.0 0.77 128400.0 5160.0 0.48 0.886 0.9731 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O08 mock treatment 132400.0 4420.0 0.41 130400.0 7160.0 0.66 0.7569 0.9724 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O09 mock treatment 134400.0 6420.0 0.59 124000.0 759.0 0.07 0.4675 0.7858 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O10 mock treatment 123600.0 -4380.0 -0.4 126800.0 3560.0 0.33 -0.0514 -0.0988 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O11 mock treatment 136400.0 8420.0 0.77 132800.0 9560.0 0.89 1.1744 0.9978 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O12 mock treatment 126000.0 -1980.0 -0.18 124800.0 1560.0 0.14 -0.0264 -0.1137 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O13 mock treatment 136000.0 8020.0 0.74 119600.0 -3640.0 -0.34 0.2832 0.349 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O14 mock treatment 138800.0 10800.0 1.0 120400.0 -2840.0 -0.26 0.5177 0.5028 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O15 mock treatment 131200.0 3220.0 0.3 119200.0 -4040.0 -0.37 -0.0552 -0.1156 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O16 mock treatment 133600.0 5620.0 0.52 132000.0 8760.0 0.81 0.9398 0.9763 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O17 mock treatment 130400.0 2420.0 0.22 120000.0 -3240.0 -0.3 -0.0548 -0.1466 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O18 mock treatment 137600.0 9620.0 0.89 127600.0 4360.0 0.4 0.9116 0.9369 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O19 mock treatment 129600.0 1620.0 0.15 126400.0 3160.0 0.29 0.3126 0.9511 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O20 mock treatment 133600.0 5620.0 0.52 134800.0 11600.0 1.07 1.1233 0.9442 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O21 mock treatment 141600.0 13600.0 1.25 133600.0 10400.0 0.96 1.565 0.9914 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O22 mock treatment 130800.0 2820.0 0.26 131200.0 7960.0 0.74 0.7053 0.9018 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O23 mock treatment 142400.0 14400.0 1.33 129200.0 5960.0 0.55 1.3287 0.9246 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 O24 mock treatment 132800.0 4820.0 0.44 128000.0 4760.0 0.44 0.6256 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P01 compound treatment 118800.0 -9180.0 -0.84 115200.0 -8040.0 -0.75 -1.1239 -0.9981 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P02 compound treatment 149200.0 21200.0 1.95 151200.0 28000.0 2.59 3.2129 0.9902 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P03 compound treatment 153600.0 25600.0 2.36 158800.0 35600.0 3.3 3.9972 0.9865 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P04 compound treatment 94400.0 -33600.0 -3.09 85600.0 -37600.0 -3.49 -4.651 -0.9982 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P05 compound treatment 156400.0 28400.0 2.61 152800.0 29600.0 2.74 3.786 0.9997 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P06 compound treatment 128800.0 823.0 0.08 122000.0 -1240.0 -0.12 -0.0278 -0.2021 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P07 compound treatment 136000.0 8020.0 0.74 130800.0 7560.0 0.7 1.0173 0.9997 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P08 compound treatment 93200.0 -34800.0 -3.2 93200.0 -30000.0 -2.78 -4.2309 -0.9976 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P09 compound treatment 141200.0 13200.0 1.22 131200.0 7960.0 0.74 1.3817 0.9713 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P10 compound treatment 118800.0 -9180.0 -0.84 115200.0 -8040.0 -0.75 -1.1239 -0.9981 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P11 mock treatment 120800.0 -7180.0 -0.66 128800.0 5560.0 0.52 -0.1025 -0.1224 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P12 mock treatment 129600.0 1620.0 0.15 130800.0 7560.0 0.7 0.601 0.8389 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P13 compound treatment 138800.0 10800.0 1.0 133600.0 10400.0 0.96 1.3829 0.9998 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P14 compound treatment 69200.0 -58800.0 -5.41 74000.0 -49200.0 -4.56 -7.0504 -0.9964 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P15 compound treatment 130400.0 2420.0 0.22 131600.0 8360.0 0.77 0.7055 0.875 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P16 compound treatment 116400.0 -11600.0 -1.06 119600.0 -3640.0 -0.34 -0.9916 -0.8877 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P17 compound treatment 128400.0 423.0 0.04 127200.0 3960.0 0.37 0.287 0.7777 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P18 compound treatment 87200.0 -40800.0 -3.75 101600.0 -21600.0 -2.01 -4.0706 -0.957 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P19 compound treatment 134800.0 6820.0 0.63 136000.0 12800.0 1.18 1.28 0.9561 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P20 compound treatment 81200.0 -46800.0 -4.3 85600.0 -37600.0 -3.49 -5.5096 -0.9946 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P21 compound treatment 140400.0 12400.0 1.14 124400.0 1160.0 0.11 0.884 0.7702 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P22 compound treatment 137600.0 9620.0 0.89 129600.0 6360.0 0.59 1.0427 0.9805 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P23 compound treatment 136800.0 8820.0 0.81 140000.0 16800.0 1.55 1.6723 0.9542 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.2130 P24 compound treatment 108800.0 -19200.0 -1.76 110000.0 -13200.0 -1.23 -2.1152 -0.9843 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A01 mock treatment 84400.0 -1020.0 -0.09 84800.0 930.0 0.09 -0.0056 -0.0435 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A02 mock treatment 83600.0 -1820.0 -0.17 83600.0 -270.0 -0.03 -0.1362 -0.8039 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A03 mock treatment 88000.0 2580.0 0.24 82000.0 -1870.0 -0.17 0.0451 0.1535 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A04 mock treatment 81600.0 -3820.0 -0.35 84400.0 530.0 0.05 -0.2139 -0.6025 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A05 mock treatment 88000.0 2580.0 0.24 81600.0 -2270.0 -0.21 0.0189 0.0595 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A06 mock treatment 86000.0 578.0 0.05 82000.0 -1870.0 -0.17 -0.085 -0.4687 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A07 mock treatment 86000.0 578.0 0.05 77200.0 -6670.0 -0.62 -0.3996 -0.6439 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A08 mock treatment 85200.0 -222.0 -0.02 87600.0 3730.0 0.35 0.23 0.6642 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A09 mock treatment 88000.0 2580.0 0.24 81200.0 -2670.0 -0.25 -0.0073 -0.0214 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A10 mock treatment 88400.0 2980.0 0.27 83200.0 -670.0 -0.06 0.1498 0.5331 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A11 mock treatment 84400.0 -1020.0 -0.09 82000.0 -1870.0 -0.17 -0.1891 -0.9587 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A12 mock treatment 86000.0 578.0 0.05 85600.0 1730.0 0.16 0.151 0.8938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A13 mock treatment 79200.0 -6220.0 -0.57 86400.0 2530.0 0.23 -0.2389 -0.3863 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A14 mock treatment 88800.0 3380.0 0.31 84000.0 130.0 0.01 0.2282 0.7339 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A15 mock treatment 83600.0 -1820.0 -0.17 84400.0 530.0 0.05 -0.0838 -0.4799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A16 mock treatment 80400.0 -5020.0 -0.46 80800.0 -3070.0 -0.28 -0.5279 -0.9729 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A17 mock treatment 78400.0 -7020.0 -0.65 85200.0 1330.0 0.12 -0.3696 -0.5621 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A18 mock treatment 86800.0 1380.0 0.13 84400.0 530.0 0.05 0.1243 0.9147 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A19 mock treatment 76800.0 -8620.0 -0.79 88800.0 4930.0 0.46 -0.2377 -0.2597 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A20 mock treatment 84000.0 -1420.0 -0.13 85600.0 1730.0 0.16 0.0209 0.1008 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A21 mock treatment 91600.0 6180.0 0.57 84000.0 130.0 0.01 0.4103 0.7219 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A22 mock treatment 94000.0 8580.0 0.79 84000.0 130.0 0.01 0.5664 0.7178 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A23 mock treatment 87600.0 2180.0 0.2 90800.0 6930.0 0.64 0.5958 0.8856 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base A24 mock treatment 84000.0 -1420.0 -0.13 93600.0 9730.0 0.9 0.5452 0.5983 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B01 mock treatment 84000.0 -1420.0 -0.13 89600.0 5730.0 0.53 0.283 0.5175 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B02 mock treatment 89600.0 4180.0 0.38 92400.0 8530.0 0.79 0.8308 0.9451 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B03 mock treatment 87600.0 2180.0 0.2 88400.0 4530.0 0.42 0.4385 0.9427 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B04 mock treatment 91600.0 6180.0 0.57 90000.0 6130.0 0.57 0.8036 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B05 mock treatment 85200.0 -222.0 -0.02 86000.0 2130.0 0.2 0.1251 0.6306 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B06 mock treatment 95200.0 9780.0 0.9 82800.0 -1070.0 -0.1 0.5658 0.6253 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B07 mock treatment 94400.0 8980.0 0.83 84400.0 530.0 0.05 0.6187 0.7478 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B08 mock treatment 96400.0 11000.0 1.01 92000.0 8130.0 0.75 1.2469 0.9896 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B09 mock treatment 96400.0 11000.0 1.01 85200.0 1330.0 0.12 0.8012 0.7876 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B10 mock treatment 96000.0 10600.0 0.97 83200.0 -670.0 -0.06 0.6441 0.6606 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B11 mock treatment 83600.0 -1820.0 -0.17 82400.0 -1470.0 -0.14 -0.2149 -0.9947 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B12 mock treatment 94800.0 9380.0 0.86 86000.0 2130.0 0.2 0.7495 0.847 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B13 mock treatment 92000.0 6580.0 0.61 82800.0 -1070.0 -0.1 0.3577 0.5834 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B14 mock treatment 88400.0 2980.0 0.27 88000.0 4130.0 0.38 0.4644 0.9865 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B15 mock treatment 85200.0 -222.0 -0.02 88400.0 4530.0 0.42 0.2824 0.6719 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B16 mock treatment 90400.0 4980.0 0.46 88800.0 4930.0 0.46 0.6469 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B17 mock treatment 85200.0 -222.0 -0.02 88000.0 4130.0 0.38 0.2562 0.6684 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B18 mock treatment 87600.0 2180.0 0.2 95200.0 11300.0 1.05 0.8842 0.8271 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B19 mock treatment 91600.0 6180.0 0.57 84400.0 530.0 0.05 0.4365 0.7653 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B20 mock treatment 84000.0 -1420.0 -0.13 90400.0 6530.0 0.61 0.3355 0.5418 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B21 mock treatment 84800.0 -622.0 -0.06 91600.0 7730.0 0.72 0.4662 0.6486 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B22 mock treatment 88400.0 2980.0 0.27 86800.0 2930.0 0.27 0.3857 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B23 mock treatment 96400.0 11000.0 1.01 96000.0 12100.0 1.12 1.509 0.9986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base B24 mock treatment 92000.0 6580.0 0.61 92400.0 8530.0 0.79 0.9869 0.9913 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C01 mock treatment 84000.0 -1420.0 -0.13 88000.0 4130.0 0.38 0.1782 0.4405 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C02 mock treatment 81600.0 -3820.0 -0.35 87200.0 3330.0 0.31 -0.0304 -0.0649 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C03 mock treatment 95200.0 9780.0 0.9 80400.0 -3470.0 -0.32 0.4085 0.4277 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C04 mock treatment 88000.0 2580.0 0.24 86400.0 2530.0 0.23 0.3335 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C05 mock treatment 87200.0 1780.0 0.16 80400.0 -3470.0 -0.32 -0.1118 -0.3099 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C06 mock treatment 91200.0 5780.0 0.53 85600.0 1730.0 0.16 0.4892 0.8812 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C07 mock treatment 87200.0 1780.0 0.16 89200.0 5330.0 0.49 0.465 0.8935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C08 mock treatment 92000.0 6580.0 0.61 86000.0 2130.0 0.2 0.5674 0.8915 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C09 mock treatment 78000.0 -7420.0 -0.68 83200.0 -670.0 -0.06 -0.5267 -0.7683 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C10 mock treatment 86000.0 578.0 0.05 80800.0 -3070.0 -0.28 -0.1637 -0.5652 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C11 mock treatment 85600.0 178.0 0.02 78000.0 -5870.0 -0.54 -0.3732 -0.6855 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C12 mock treatment 81600.0 -3820.0 -0.35 81600.0 -2270.0 -0.21 -0.3974 -0.9699 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C13 mock treatment 85200.0 -222.0 -0.02 83200.0 -670.0 -0.06 -0.0584 -0.8925 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C14 mock treatment 82400.0 -3020.0 -0.28 78400.0 -5470.0 -0.51 -0.5551 -0.96 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C15 mock treatment 83600.0 -1820.0 -0.17 84400.0 530.0 0.05 -0.0838 -0.4799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C16 mock treatment 84400.0 -1020.0 -0.09 78000.0 -5870.0 -0.54 -0.4512 -0.8172 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C17 mock treatment 89200.0 3780.0 0.35 85600.0 1730.0 0.16 0.3591 0.9383 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C18 mock treatment 83600.0 -1820.0 -0.17 85200.0 1330.0 0.12 -0.0314 -0.1508 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C19 mock treatment 83600.0 -1820.0 -0.17 86800.0 2930.0 0.27 0.0735 0.2303 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C20 mock treatment 84400.0 -1020.0 -0.09 86000.0 2130.0 0.2 0.0731 0.3344 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C21 mock treatment 87200.0 1780.0 0.16 87600.0 3730.0 0.35 0.3601 0.9416 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C22 mock treatment 93600.0 8180.0 0.75 88800.0 4930.0 0.46 0.855 0.9714 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C23 mock treatment 90800.0 5380.0 0.49 92400.0 8530.0 0.79 0.9088 0.9745 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base C24 mock treatment 90000.0 4580.0 0.42 99600.0 15700.0 1.46 1.3287 0.8756 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D01 mock treatment 88000.0 2580.0 0.24 86800.0 2930.0 0.27 0.3597 0.9977 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D02 mock treatment 92800.0 7380.0 0.68 91600.0 7730.0 0.72 0.9865 0.9996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D03 mock treatment 92000.0 6580.0 0.61 83200.0 -670.0 -0.06 0.3839 0.6312 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D04 mock treatment 88800.0 3380.0 0.31 90800.0 6930.0 0.64 0.6739 0.9445 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D05 mock treatment 83200.0 -2220.0 -0.2 88400.0 4530.0 0.42 0.1523 0.3263 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D06 mock treatment 92400.0 6980.0 0.64 83200.0 -670.0 -0.06 0.4099 0.6357 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D07 mock treatment 90000.0 4580.0 0.42 86800.0 2930.0 0.27 0.4898 0.9775 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D08 mock treatment 86800.0 1380.0 0.13 84800.0 930.0 0.09 0.1506 0.9823 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D09 mock treatment 87600.0 2180.0 0.2 84800.0 930.0 0.09 0.2026 0.9289 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D10 mock treatment 82800.0 -2620.0 -0.24 79200.0 -4670.0 -0.43 -0.4767 -0.9619 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D11 mock treatment 86400.0 978.0 0.09 83200.0 -670.0 -0.06 0.0197 0.1799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D12 mock treatment 83200.0 -2220.0 -0.2 82800.0 -1070.0 -0.1 -0.2147 -0.9449 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D13 mock treatment 87600.0 2180.0 0.2 81600.0 -2270.0 -0.21 -0.0071 -0.0246 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D14 mock treatment 86000.0 578.0 0.05 85200.0 1330.0 0.12 0.1247 0.9294 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D15 mock treatment 78800.0 -6620.0 -0.61 85600.0 1730.0 0.16 -0.3174 -0.5039 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D16 mock treatment 83600.0 -1820.0 -0.17 86000.0 2130.0 0.2 0.0211 0.0814 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D17 mock treatment 81200.0 -4220.0 -0.39 82800.0 -1070.0 -0.1 -0.3448 -0.8601 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D18 mock treatment 80000.0 -5420.0 -0.5 82400.0 -1470.0 -0.14 -0.449 -0.8685 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D19 mock treatment 84800.0 -622.0 -0.06 94400.0 10500.0 0.98 0.6497 0.6645 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D20 mock treatment 82800.0 -2620.0 -0.24 86400.0 2530.0 0.23 -0.0048 -0.0141 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D21 mock treatment 85200.0 -222.0 -0.02 81600.0 -2270.0 -0.21 -0.1633 -0.7721 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D22 mock treatment 87200.0 1780.0 0.16 86800.0 2930.0 0.27 0.3077 0.9706 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D23 mock treatment 89200.0 3780.0 0.35 95200.0 11300.0 1.05 0.9883 0.8935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base D24 mock treatment 89600.0 4180.0 0.38 89600.0 5730.0 0.53 0.6473 0.9874 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E01 mock treatment 84400.0 -1020.0 -0.09 78800.0 -5070.0 -0.47 -0.3988 -0.8321 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E02 mock treatment 82800.0 -2620.0 -0.24 80400.0 -3470.0 -0.32 -0.398 -0.9899 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E03 mock treatment 80400.0 -5020.0 -0.46 80800.0 -3070.0 -0.28 -0.5279 -0.9729 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E04 mock treatment 81200.0 -4220.0 -0.39 78000.0 -5870.0 -0.54 -0.6594 -0.9863 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E05 mock treatment 85600.0 178.0 0.02 80000.0 -3870.0 -0.36 -0.2421 -0.6741 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E06 mock treatment 87600.0 2180.0 0.2 75200.0 -8670.0 -0.8 -0.4266 -0.5151 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E07 mock treatment 85600.0 178.0 0.02 79600.0 -4270.0 -0.4 -0.2683 -0.6773 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E08 mock treatment 87600.0 2180.0 0.2 84000.0 130.0 0.01 0.1502 0.7481 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E09 mock treatment 85200.0 -222.0 -0.02 77600.0 -6270.0 -0.58 -0.4254 -0.7315 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E10 mock treatment 86400.0 978.0 0.09 78400.0 -5470.0 -0.51 -0.2949 -0.5727 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E11 mock treatment 86400.0 978.0 0.09 81200.0 -2670.0 -0.25 -0.1114 -0.423 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E12 mock treatment 87200.0 1780.0 0.16 86000.0 2130.0 0.2 0.2552 0.9956 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E13 mock treatment 84000.0 -1420.0 -0.13 76000.0 -7870.0 -0.73 -0.6083 -0.8208 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E14 mock treatment 79200.0 -6220.0 -0.57 85200.0 1330.0 0.12 -0.3176 -0.5424 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E15 mock treatment 80400.0 -5020.0 -0.46 88000.0 4130.0 0.38 -0.056 -0.0933 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E16 mock treatment 77200.0 -8220.0 -0.76 82400.0 -1470.0 -0.14 -0.6312 -0.8213 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E17 mock treatment 81600.0 -3820.0 -0.35 81600.0 -2270.0 -0.21 -0.3974 -0.9699 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E18 mock treatment 76800.0 -8620.0 -0.79 87200.0 3330.0 0.31 -0.3426 -0.4025 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E19 mock treatment 82800.0 -2620.0 -0.24 78800.0 -5070.0 -0.47 -0.5029 -0.9519 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E20 mock treatment 86000.0 578.0 0.05 87600.0 3730.0 0.35 0.282 0.8064 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E21 mock treatment 82000.0 -3420.0 -0.31 88800.0 4930.0 0.46 0.1005 0.1812 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E22 mock treatment 88400.0 2980.0 0.27 86400.0 2530.0 0.23 0.3595 0.997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E23 mock treatment 92800.0 7380.0 0.68 90000.0 6130.0 0.57 0.8816 0.9961 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base E24 mock treatment 88400.0 2980.0 0.27 90800.0 6930.0 0.64 0.6479 0.9278 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F01 mock treatment 84400.0 -1020.0 -0.09 84400.0 530.0 0.05 -0.0318 -0.2996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F02 mock treatment 83200.0 -2220.0 -0.2 88400.0 4530.0 0.42 0.1523 0.3263 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F03 mock treatment 81200.0 -4220.0 -0.39 75200.0 -8670.0 -0.8 -0.8429 -0.9443 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F04 mock treatment 79200.0 -6220.0 -0.57 81200.0 -2670.0 -0.25 -0.5797 -0.9297 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F05 mock treatment 83600.0 -1820.0 -0.17 78000.0 -5870.0 -0.54 -0.5033 -0.8839 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F06 mock treatment 81600.0 -3820.0 -0.35 78800.0 -5070.0 -0.47 -0.5809 -0.9898 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F07 mock treatment 79600.0 -5820.0 -0.54 78800.0 -5070.0 -0.47 -0.711 -0.9979 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F08 mock treatment 81600.0 -3820.0 -0.35 74800.0 -9070.0 -0.84 -0.8431 -0.9252 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F09 mock treatment 74000.0 -11400.0 -1.05 73200.0 -10700.0 -0.99 -1.4423 -0.9995 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F10 mock treatment 73600.0 -11800.0 -1.09 85600.0 1730.0 0.16 -0.6556 -0.5964 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F11 mock treatment 75200.0 -10200.0 -0.94 73600.0 -10300.0 -0.95 -1.338 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F12 mock treatment 77600.0 -7820.0 -0.72 79200.0 -4670.0 -0.43 -0.8149 -0.9704 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F13 mock treatment 78400.0 -7020.0 -0.65 76800.0 -7070.0 -0.66 -0.9201 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F14 mock treatment 76000.0 -9420.0 -0.87 81600.0 -2270.0 -0.21 -0.7616 -0.854 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F15 mock treatment 73200.0 -12200.0 -1.12 78400.0 -5470.0 -0.51 -1.1535 -0.9353 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F16 mock treatment 70400.0 -15000.0 -1.38 82800.0 -1070.0 -0.1 -1.0472 -0.7559 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F17 mock treatment 72400.0 -13000.0 -1.2 71600.0 -12300.0 -1.14 -1.6512 -0.9997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F18 mock treatment 77200.0 -8220.0 -0.76 73600.0 -10300.0 -0.95 -1.2079 -0.9935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F19 mock treatment 80400.0 -5020.0 -0.46 80400.0 -3470.0 -0.32 -0.5541 -0.9844 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F20 mock treatment 78000.0 -7420.0 -0.68 75200.0 -8670.0 -0.8 -1.051 -0.9967 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F21 mock treatment 74400.0 -11000.0 -1.01 88800.0 4930.0 0.46 -0.3938 -0.3541 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F22 mock treatment 83600.0 -1820.0 -0.17 84400.0 530.0 0.05 -0.0838 -0.4799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F23 mock treatment 85600.0 178.0 0.02 84400.0 530.0 0.05 0.0463 0.8945 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base F24 mock treatment 86000.0 578.0 0.05 85600.0 1730.0 0.16 0.151 0.8938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G01 mock treatment 87200.0 1780.0 0.16 80000.0 -3870.0 -0.36 -0.138 -0.3501 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G02 mock treatment 82800.0 -2620.0 -0.24 80400.0 -3470.0 -0.32 -0.398 -0.9899 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G03 mock treatment 85200.0 -222.0 -0.02 82400.0 -1470.0 -0.14 -0.1108 -0.8041 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G04 mock treatment 86400.0 978.0 0.09 83600.0 -270.0 -0.03 0.0459 0.4913 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G05 mock treatment 84800.0 -622.0 -0.06 80800.0 -3070.0 -0.28 -0.2417 -0.8326 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G06 mock treatment 84000.0 -1420.0 -0.13 80400.0 -3470.0 -0.32 -0.32 -0.9214 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G07 mock treatment 83200.0 -2220.0 -0.2 79600.0 -4270.0 -0.4 -0.4244 -0.9527 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G08 mock treatment 85600.0 178.0 0.02 79200.0 -4670.0 -0.43 -0.2945 -0.6799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G09 mock treatment 78400.0 -7020.0 -0.65 79600.0 -4270.0 -0.4 -0.7366 -0.9724 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G10 mock treatment 81200.0 -4220.0 -0.39 79600.0 -4270.0 -0.4 -0.5545 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G11 mock treatment 82400.0 -3020.0 -0.28 79600.0 -4270.0 -0.4 -0.4765 -0.985 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G12 mock treatment 78400.0 -7020.0 -0.65 77600.0 -6270.0 -0.58 -0.8677 -0.9986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G13 mock treatment 78400.0 -7020.0 -0.65 79200.0 -4670.0 -0.43 -0.7628 -0.9811 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G14 mock treatment 77600.0 -7820.0 -0.72 76800.0 -7070.0 -0.66 -0.9722 -0.9989 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G15 mock treatment 78000.0 -7420.0 -0.68 79200.0 -4670.0 -0.43 -0.7889 -0.9758 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G16 mock treatment 82000.0 -3420.0 -0.31 78400.0 -5470.0 -0.51 -0.5811 -0.9737 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G17 mock treatment 81600.0 -3820.0 -0.35 80800.0 -3070.0 -0.28 -0.4498 -0.9945 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G18 mock treatment 78000.0 -7420.0 -0.68 82800.0 -1070.0 -0.1 -0.5529 -0.8015 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G19 mock treatment 86800.0 1380.0 0.13 84000.0 130.0 0.01 0.0981 0.7706 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G20 mock treatment 76400.0 -9020.0 -0.83 82400.0 -1470.0 -0.14 -0.6832 -0.8124 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G21 mock treatment 75600.0 -9820.0 -0.9 83200.0 -670.0 -0.06 -0.6828 -0.754 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G22 mock treatment 83200.0 -2220.0 -0.2 79200.0 -4670.0 -0.43 -0.4506 -0.9413 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G23 mock treatment 88400.0 2980.0 0.27 86400.0 2530.0 0.23 0.3595 0.997 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base G24 mock treatment 90400.0 4980.0 0.46 82400.0 -1470.0 -0.14 0.2274 0.476 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H01 mock treatment 87200.0 1780.0 0.16 85200.0 1330.0 0.12 0.2028 0.9903 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H02 mock treatment 85200.0 -222.0 -0.02 84800.0 930.0 0.09 0.0465 0.525 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H03 mock treatment 85200.0 -222.0 -0.02 89600.0 5730.0 0.53 0.3611 0.6794 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H04 mock treatment 82000.0 -3420.0 -0.31 83600.0 -270.0 -0.03 -0.2403 -0.761 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H05 mock treatment 83600.0 -1820.0 -0.17 82000.0 -1870.0 -0.17 -0.2411 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H06 mock treatment 81600.0 -3820.0 -0.35 83600.0 -270.0 -0.03 -0.2663 -0.7556 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H07 mock treatment 85600.0 178.0 0.02 81600.0 -2270.0 -0.21 -0.1372 -0.6501 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H08 mock treatment 78800.0 -6620.0 -0.61 79200.0 -4670.0 -0.43 -0.7368 -0.986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H09 mock treatment 80400.0 -5020.0 -0.46 73600.0 -10300.0 -0.95 -0.9998 -0.9449 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H10 mock treatment 80000.0 -5420.0 -0.5 78800.0 -5070.0 -0.47 -0.685 -0.9996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H11 mock treatment 84000.0 -1420.0 -0.13 82000.0 -1870.0 -0.17 -0.2151 -0.9903 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H12 mock treatment 87200.0 1780.0 0.16 84800.0 930.0 0.09 0.1766 0.9552 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H13 mock treatment 78800.0 -6620.0 -0.61 75600.0 -8270.0 -0.77 -0.9728 -0.9935 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H14 mock treatment 83600.0 -1820.0 -0.17 79200.0 -4670.0 -0.43 -0.4246 -0.9147 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H15 mock treatment 80000.0 -5420.0 -0.5 82000.0 -1870.0 -0.17 -0.4753 -0.9001 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H16 mock treatment 79200.0 -6220.0 -0.57 77200.0 -6670.0 -0.62 -0.8419 -0.9993 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H17 mock treatment 78000.0 -7420.0 -0.68 73200.0 -10700.0 -0.99 -1.1821 -0.9836 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H18 mock treatment 80800.0 -4620.0 -0.43 82800.0 -1070.0 -0.1 -0.3708 -0.8493 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H19 mock treatment 78400.0 -7020.0 -0.65 78000.0 -5870.0 -0.54 -0.8415 -0.9964 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H20 mock treatment 82400.0 -3020.0 -0.28 82000.0 -1870.0 -0.17 -0.3192 -0.9742 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H21 mock treatment 86800.0 1380.0 0.13 84400.0 530.0 0.05 0.1243 0.9147 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H22 mock treatment 83600.0 -1820.0 -0.17 88800.0 4930.0 0.46 0.2046 0.4204 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H23 mock treatment 88400.0 2980.0 0.27 90400.0 6530.0 0.61 0.6217 0.9358 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base H24 mock treatment 94000.0 8580.0 0.79 87600.0 3730.0 0.35 0.8024 0.9314 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I01 mock treatment 95600.0 10200.0 0.94 91200.0 7330.0 0.68 1.1424 0.9876 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I02 mock treatment 82400.0 -3020.0 -0.28 86000.0 2130.0 0.2 -0.057 -0.1672 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I03 mock treatment 86800.0 1380.0 0.13 86000.0 2130.0 0.2 0.2292 0.9771 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I04 mock treatment 88800.0 3380.0 0.31 90400.0 6530.0 0.61 0.6477 0.952 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I05 mock treatment 87600.0 2180.0 0.2 80000.0 -3870.0 -0.36 -0.112 -0.2726 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I06 mock treatment 86800.0 1380.0 0.13 78400.0 -5470.0 -0.51 -0.2689 -0.5145 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I07 mock treatment 88800.0 3380.0 0.31 81600.0 -2270.0 -0.21 0.0709 0.1889 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I08 mock treatment 80400.0 -5020.0 -0.46 76800.0 -7070.0 -0.66 -0.7901 -0.9853 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I09 mock treatment 81600.0 -3820.0 -0.35 78800.0 -5070.0 -0.47 -0.5809 -0.9898 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I10 mock treatment 81600.0 -3820.0 -0.35 79200.0 -4670.0 -0.43 -0.5547 -0.9947 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I11 mock treatment 76000.0 -9420.0 -0.87 80000.0 -3870.0 -0.36 -0.8665 -0.9238 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I12 mock treatment 76800.0 -8620.0 -0.79 81200.0 -2670.0 -0.25 -0.7358 -0.8857 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I13 mock treatment 80400.0 -5020.0 -0.46 78400.0 -5470.0 -0.51 -0.6852 -0.9989 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I14 mock treatment 84000.0 -1420.0 -0.13 80400.0 -3470.0 -0.32 -0.32 -0.9214 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I15 mock treatment 80000.0 -5420.0 -0.5 78400.0 -5470.0 -0.51 -0.7112 -1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I16 mock treatment 80000.0 -5420.0 -0.5 84400.0 530.0 0.05 -0.318 -0.6345 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I17 mock treatment 85600.0 178.0 0.02 77600.0 -6270.0 -0.58 -0.3994 -0.6869 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I18 mock treatment 86400.0 978.0 0.09 86800.0 2930.0 0.27 0.2556 0.8936 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I19 mock treatment 83200.0 -2220.0 -0.2 83600.0 -270.0 -0.03 -0.1623 -0.7879 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I20 mock treatment 83200.0 -2220.0 -0.2 81200.0 -2670.0 -0.25 -0.3196 -0.9955 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I21 mock treatment 85200.0 -222.0 -0.02 89600.0 5730.0 0.53 0.3611 0.6794 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I22 mock treatment 89600.0 4180.0 0.38 86400.0 2530.0 0.23 0.4375 0.9719 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I23 mock treatment 91600.0 6180.0 0.57 86400.0 2530.0 0.23 0.5676 0.9233 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base I24 mock treatment 94000.0 8580.0 0.79 91200.0 7330.0 0.68 1.0383 0.9972 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J01 mock treatment 93600.0 8180.0 0.75 84800.0 930.0 0.09 0.5928 0.783 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J02 mock treatment 89200.0 3780.0 0.35 91200.0 7330.0 0.68 0.7261 0.9515 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J03 mock treatment 99200.0 13800.0 1.27 77200.0 -6670.0 -0.62 0.459 0.3255 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J04 mock treatment 88800.0 3380.0 0.31 77200.0 -6670.0 -0.62 -0.2175 -0.3143 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J05 mock treatment 88400.0 2980.0 0.27 83200.0 -670.0 -0.06 0.1498 0.5331 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J06 mock treatment 83200.0 -2220.0 -0.2 85600.0 1730.0 0.16 -0.0312 -0.12 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J07 mock treatment 81600.0 -3820.0 -0.35 81200.0 -2670.0 -0.25 -0.4236 -0.9853 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J08 mock treatment 80400.0 -5020.0 -0.46 81200.0 -2670.0 -0.25 -0.5017 -0.9572 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J09 mock treatment 81200.0 -4220.0 -0.39 78000.0 -5870.0 -0.54 -0.6594 -0.9863 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J10 mock treatment 86800.0 1380.0 0.13 74800.0 -9070.0 -0.84 -0.5049 -0.5938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J11 mock treatment 84000.0 -1420.0 -0.13 72400.0 -11500.0 -1.06 -0.8443 -0.7882 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J12 mock treatment 86000.0 578.0 0.05 79600.0 -4270.0 -0.4 -0.2423 -0.6067 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J13 mock treatment 77200.0 -8220.0 -0.76 77200.0 -6670.0 -0.62 -0.972 -0.995 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J14 mock treatment 75600.0 -9820.0 -0.9 81200.0 -2670.0 -0.25 -0.8139 -0.8688 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J15 mock treatment 78800.0 -6620.0 -0.61 82400.0 -1470.0 -0.14 -0.5271 -0.8445 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J16 mock treatment 77600.0 -7820.0 -0.72 78400.0 -5470.0 -0.51 -0.8673 -0.9853 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J17 mock treatment 80000.0 -5420.0 -0.5 82800.0 -1070.0 -0.1 -0.4228 -0.8315 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J18 mock treatment 84000.0 -1420.0 -0.13 84000.0 130.0 0.01 -0.084 -0.6395 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J19 mock treatment 81600.0 -3820.0 -0.35 79600.0 -4270.0 -0.4 -0.5285 -0.9983 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J20 mock treatment 83200.0 -2220.0 -0.2 88400.0 4530.0 0.42 0.1523 0.3263 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J21 mock treatment 88400.0 2980.0 0.27 81600.0 -2270.0 -0.21 0.0449 0.1299 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J22 mock treatment 86800.0 1380.0 0.13 85200.0 1330.0 0.12 0.1768 0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J23 mock treatment 85600.0 178.0 0.02 90400.0 6530.0 0.61 0.4395 0.726 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base J24 mock treatment 92000.0 6580.0 0.61 88000.0 4130.0 0.38 0.6985 0.9756 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K01 mock treatment 90800.0 5380.0 0.49 81600.0 -2270.0 -0.21 0.201 0.3739 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K02 mock treatment 88400.0 2980.0 0.27 75200.0 -8670.0 -0.8 -0.3746 -0.4412 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K03 mock treatment 91200.0 5780.0 0.53 79200.0 -4670.0 -0.43 0.0697 0.1017 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K04 mock treatment 84000.0 -1420.0 -0.13 80400.0 -3470.0 -0.32 -0.32 -0.9214 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K05 mock treatment 81600.0 -3820.0 -0.35 77200.0 -6670.0 -0.62 -0.6858 -0.9642 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K06 mock treatment 86000.0 578.0 0.05 82400.0 -1470.0 -0.14 -0.0588 -0.4018 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K07 mock treatment 84000.0 -1420.0 -0.13 80400.0 -3470.0 -0.32 -0.32 -0.9214 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K08 mock treatment 84400.0 -1020.0 -0.09 84400.0 530.0 0.05 -0.0318 -0.2996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K09 mock treatment 77200.0 -8220.0 -0.76 78800.0 -5070.0 -0.47 -0.8671 -0.9738 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K10 mock treatment 78000.0 -7420.0 -0.68 80000.0 -3870.0 -0.36 -0.7364 -0.9549 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K11 mock treatment 79200.0 -6220.0 -0.57 83600.0 -270.0 -0.03 -0.4224 -0.7374 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K12 mock treatment 83200.0 -2220.0 -0.2 73200.0 -10700.0 -0.99 -0.8439 -0.8356 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K13 mock treatment 73600.0 -11800.0 -1.09 81600.0 -2270.0 -0.21 -0.9177 -0.8286 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K14 mock treatment 79600.0 -5820.0 -0.54 84400.0 530.0 0.05 -0.344 -0.6396 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K15 mock treatment 77200.0 -8220.0 -0.76 76000.0 -7870.0 -0.73 -1.0506 -0.9998 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K16 mock treatment 78800.0 -6620.0 -0.61 80000.0 -3870.0 -0.36 -0.6844 -0.9681 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K17 mock treatment 81600.0 -3820.0 -0.35 74800.0 -9070.0 -0.84 -0.8431 -0.9252 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K18 mock treatment 76800.0 -8620.0 -0.79 81200.0 -2670.0 -0.25 -0.7358 -0.8857 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K19 mock treatment 86400.0 978.0 0.09 91200.0 7330.0 0.68 0.544 0.7938 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K20 mock treatment 75200.0 -10200.0 -0.94 92000.0 8130.0 0.75 -0.132 -0.1096 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K21 mock treatment 91600.0 6180.0 0.57 86800.0 2930.0 0.27 0.5938 0.9429 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K22 mock treatment 86800.0 1380.0 0.13 90000.0 6130.0 0.57 0.4914 0.8441 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K23 mock treatment 88000.0 2580.0 0.24 88800.0 4930.0 0.46 0.4908 0.9533 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base K24 mock treatment 83600.0 -1820.0 -0.17 89200.0 5330.0 0.49 0.2308 0.4424 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L01 mock treatment 86400.0 978.0 0.09 79200.0 -4670.0 -0.43 -0.2425 -0.5484 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L02 mock treatment 93600.0 8180.0 0.75 85200.0 1330.0 0.12 0.6191 0.8121 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L03 mock treatment 95600.0 10200.0 0.94 91200.0 7330.0 0.68 1.1424 0.9876 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L04 mock treatment 94800.0 9380.0 0.86 84000.0 130.0 0.01 0.6185 0.7169 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L05 mock treatment 84800.0 -622.0 -0.06 78400.0 -5470.0 -0.51 -0.399 -0.7819 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L06 mock treatment 92800.0 7380.0 0.68 86000.0 2130.0 0.2 0.6195 0.8764 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L07 mock treatment 84000.0 -1420.0 -0.13 75200.0 -8670.0 -0.8 -0.6608 -0.8115 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L08 mock treatment 80800.0 -4620.0 -0.43 82400.0 -1470.0 -0.14 -0.397 -0.8892 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L09 mock treatment 78400.0 -7020.0 -0.65 82400.0 -1470.0 -0.14 -0.5531 -0.8379 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L10 mock treatment 87600.0 2180.0 0.2 84000.0 130.0 0.01 0.1502 0.7481 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L11 mock treatment 78400.0 -7020.0 -0.65 80400.0 -3470.0 -0.32 -0.6842 -0.9482 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L12 mock treatment 86400.0 978.0 0.09 80800.0 -3070.0 -0.28 -0.1376 -0.4611 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L13 mock treatment 78800.0 -6620.0 -0.61 90400.0 6530.0 0.61 -0.0028 -0.0032 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L14 mock treatment 87600.0 2180.0 0.2 84400.0 530.0 0.05 0.1764 0.855 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L15 mock treatment 84000.0 -1420.0 -0.13 76000.0 -7870.0 -0.73 -0.6083 -0.8208 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L16 mock treatment 77600.0 -7820.0 -0.72 82400.0 -1470.0 -0.14 -0.6051 -0.8264 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L17 mock treatment 77600.0 -7820.0 -0.72 76800.0 -7070.0 -0.66 -0.9722 -0.9989 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L18 mock treatment 78400.0 -7020.0 -0.65 80400.0 -3470.0 -0.32 -0.6842 -0.9482 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L19 mock treatment 79600.0 -5820.0 -0.54 92400.0 8530.0 0.79 0.1804 0.1889 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L20 mock treatment 87600.0 2180.0 0.2 85200.0 1330.0 0.12 0.2288 0.9728 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L21 mock treatment 79600.0 -5820.0 -0.54 87200.0 3330.0 0.31 -0.1605 -0.2596 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L22 mock treatment 95200.0 9780.0 0.9 86400.0 2530.0 0.23 0.8018 0.8626 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L23 mock treatment 95600.0 10200.0 0.94 88400.0 4530.0 0.42 0.9589 0.9345 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base L24 mock treatment 90400.0 4980.0 0.46 86800.0 2930.0 0.27 0.5158 0.9689 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M01 mock treatment 95200.0 9780.0 0.9 86000.0 2130.0 0.2 0.7756 0.8422 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M02 mock treatment 88400.0 2980.0 0.27 86800.0 2930.0 0.27 0.3857 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M03 mock treatment 89600.0 4180.0 0.38 83200.0 -670.0 -0.06 0.2278 0.5852 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M04 mock treatment 87200.0 1780.0 0.16 87200.0 3330.0 0.31 0.3339 0.9559 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M05 mock treatment 86400.0 978.0 0.09 79200.0 -4670.0 -0.43 -0.2425 -0.5484 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M06 mock treatment 88800.0 3380.0 0.31 84400.0 530.0 0.05 0.2544 0.8088 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M07 mock treatment 87200.0 1780.0 0.16 80800.0 -3070.0 -0.28 -0.0856 -0.2608 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M08 mock treatment 81600.0 -3820.0 -0.35 80000.0 -3870.0 -0.36 -0.5023 -0.9999 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M09 mock treatment 82800.0 -2620.0 -0.24 79600.0 -4270.0 -0.4 -0.4504 -0.9718 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M10 mock treatment 77200.0 -8220.0 -0.76 81600.0 -2270.0 -0.21 -0.6836 -0.8708 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M11 mock treatment 82000.0 -3420.0 -0.31 76400.0 -7470.0 -0.69 -0.7122 -0.9363 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M12 mock treatment 83600.0 -1820.0 -0.17 77200.0 -6670.0 -0.62 -0.5557 -0.8675 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M13 mock treatment 82800.0 -2620.0 -0.24 83200.0 -670.0 -0.06 -0.2145 -0.8612 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M14 mock treatment 78800.0 -6620.0 -0.61 80400.0 -3470.0 -0.32 -0.6582 -0.9555 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M15 mock treatment 78000.0 -7420.0 -0.68 87200.0 3330.0 0.31 -0.2645 -0.3531 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M16 mock treatment 80400.0 -5020.0 -0.46 88400.0 4530.0 0.42 -0.0298 -0.0477 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M17 mock treatment 78800.0 -6620.0 -0.61 82000.0 -1870.0 -0.17 -0.5533 -0.8737 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M18 mock treatment 72800.0 -12600.0 -1.16 82800.0 -1070.0 -0.1 -0.8911 -0.7648 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M19 mock treatment 84800.0 -622.0 -0.06 83200.0 -670.0 -0.06 -0.0844 -0.9991 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M20 mock treatment 85200.0 -222.0 -0.02 81200.0 -2670.0 -0.25 -0.1895 -0.7628 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M21 mock treatment 84800.0 -622.0 -0.06 83600.0 -270.0 -0.03 -0.0582 -0.9315 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M22 mock treatment 94400.0 8980.0 0.83 86800.0 2930.0 0.27 0.776 0.8926 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M23 mock treatment 85200.0 -222.0 -0.02 88800.0 4930.0 0.46 0.3087 0.6748 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base M24 mock treatment 87600.0 2180.0 0.2 88000.0 4130.0 0.38 0.4123 0.9544 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N01 mock treatment 98800.0 13400.0 1.23 87200.0 3330.0 0.31 1.0884 0.8579 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N02 mock treatment 98800.0 13400.0 1.23 85200.0 1330.0 0.12 0.9573 0.774 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N03 mock treatment 96000.0 10600.0 0.97 91600.0 7730.0 0.72 1.1946 0.9887 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N04 mock treatment 89200.0 3780.0 0.35 87200.0 3330.0 0.31 0.464 0.9982 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N05 mock treatment 84800.0 -622.0 -0.06 84400.0 530.0 0.05 -0.0058 -0.0763 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N06 mock treatment 86400.0 978.0 0.09 81200.0 -2670.0 -0.25 -0.1114 -0.423 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N07 mock treatment 90400.0 4980.0 0.46 90000.0 6130.0 0.57 0.7255 0.9943 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N08 mock treatment 85200.0 -222.0 -0.02 84400.0 530.0 0.05 0.0203 0.3812 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N09 mock treatment 80400.0 -5020.0 -0.46 75600.0 -8270.0 -0.77 -0.8687 -0.9706 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N10 mock treatment 89600.0 4180.0 0.38 89200.0 5330.0 0.49 0.6211 0.9923 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N11 mock treatment 84800.0 -622.0 -0.06 78400.0 -5470.0 -0.51 -0.399 -0.7819 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N12 mock treatment 82400.0 -3020.0 -0.28 82800.0 -1070.0 -0.1 -0.2667 -0.9037 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N13 mock treatment 85200.0 -222.0 -0.02 83600.0 -270.0 -0.03 -0.0322 -0.9948 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N14 mock treatment 84000.0 -1420.0 -0.13 81600.0 -2270.0 -0.21 -0.2413 -0.9738 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N15 mock treatment 84400.0 -1020.0 -0.09 79600.0 -4270.0 -0.4 -0.3464 -0.8514 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N16 mock treatment 83600.0 -1820.0 -0.17 82800.0 -1070.0 -0.1 -0.1887 -0.9687 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N17 mock treatment 84400.0 -1020.0 -0.09 83600.0 -270.0 -0.03 -0.0842 -0.8654 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N18 mock treatment 89200.0 3780.0 0.35 87200.0 3330.0 0.31 0.464 0.9982 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N19 mock treatment 88800.0 3380.0 0.31 83200.0 -670.0 -0.06 0.1758 0.5547 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N20 mock treatment 83600.0 -1820.0 -0.17 84800.0 930.0 0.09 -0.0576 -0.3056 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N21 mock treatment 87600.0 2180.0 0.2 84800.0 930.0 0.09 0.2026 0.9289 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N22 mock treatment 93200.0 7780.0 0.72 90800.0 6930.0 0.64 0.9601 0.9986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N23 mock treatment 92800.0 7380.0 0.68 91600.0 7730.0 0.72 0.9865 0.9996 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base N24 mock treatment 91200.0 5780.0 0.53 91200.0 7330.0 0.68 0.8562 0.9926 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O01 mock treatment 94400.0 8980.0 0.83 82400.0 -1470.0 -0.14 0.4876 0.5825 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O02 mock treatment 94400.0 8980.0 0.83 90000.0 6130.0 0.57 0.9857 0.9833 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O03 mock treatment 97200.0 11800.0 1.08 86000.0 2130.0 0.2 0.9056 0.8224 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O04 mock treatment 92800.0 7380.0 0.68 92000.0 8130.0 0.75 1.0127 0.9986 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O05 mock treatment 88400.0 2980.0 0.27 85600.0 1730.0 0.16 0.3071 0.9674 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O06 mock treatment 97600.0 12200.0 1.12 86800.0 2930.0 0.27 0.9841 0.8538 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O07 mock treatment 89600.0 4180.0 0.38 84400.0 530.0 0.05 0.3065 0.791 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O08 mock treatment 83600.0 -1820.0 -0.17 87600.0 3730.0 0.35 0.1259 0.3278 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O09 mock treatment 91600.0 6180.0 0.57 87200.0 3330.0 0.31 0.6201 0.9588 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O10 mock treatment 83200.0 -2220.0 -0.2 86400.0 2530.0 0.23 0.0213 0.0684 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O11 mock treatment 92800.0 7380.0 0.68 84800.0 930.0 0.09 0.5408 0.7905 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O12 mock treatment 83600.0 -1820.0 -0.17 84400.0 530.0 0.05 -0.0838 -0.4799 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O13 mock treatment 85600.0 178.0 0.02 83600.0 -270.0 -0.03 -0.0062 -0.2054 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O14 mock treatment 84400.0 -1020.0 -0.09 83600.0 -270.0 -0.03 -0.0842 -0.8654 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O15 mock treatment 82400.0 -3020.0 -0.28 86800.0 2930.0 0.27 -0.0046 -0.0117 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O16 mock treatment 90000.0 4580.0 0.42 87200.0 3330.0 0.31 0.516 0.9883 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O17 mock treatment 86400.0 978.0 0.09 84000.0 130.0 0.01 0.0721 0.7944 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O18 mock treatment 92800.0 7380.0 0.68 86800.0 2930.0 0.27 0.6719 0.9192 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O19 mock treatment 95600.0 10200.0 0.94 82800.0 -1070.0 -0.1 0.5918 0.6286 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O20 mock treatment 94400.0 8980.0 0.83 87600.0 3730.0 0.35 0.8284 0.9253 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O21 mock treatment 87200.0 1780.0 0.16 88000.0 4130.0 0.38 0.3863 0.9281 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O22 mock treatment 94800.0 9380.0 0.86 88000.0 4130.0 0.38 0.8806 0.9331 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O23 mock treatment 97600.0 12200.0 1.12 94800.0 10900.0 1.01 1.5084 0.9987 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base O24 mock treatment 93200.0 7780.0 0.72 91600.0 7730.0 0.72 1.0125 1.0 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P01 mock treatment 90800.0 5380.0 0.49 92800.0 8930.0 0.83 0.9351 0.9697 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P02 mock treatment 100800.0 15400.0 1.41 91600.0 7730.0 0.72 1.5068 0.9503 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P03 mock treatment 95200.0 9780.0 0.9 91600.0 7730.0 0.72 1.1426 0.9937 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P04 mock treatment 97200.0 11800.0 1.08 90000.0 6130.0 0.57 1.1678 0.9546 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P05 mock treatment 94400.0 8980.0 0.83 88400.0 4530.0 0.42 0.8808 0.9508 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P06 mock treatment 89600.0 4180.0 0.38 87200.0 3330.0 0.31 0.49 0.9941 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P07 mock treatment 84400.0 -1020.0 -0.09 76800.0 -7070.0 -0.66 -0.5299 -0.8003 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P08 mock treatment 86000.0 578.0 0.05 90800.0 6930.0 0.64 0.4918 0.763 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P09 mock treatment 82400.0 -3020.0 -0.28 90400.0 6530.0 0.61 0.2314 0.3474 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P10 mock treatment 86800.0 1380.0 0.13 89600.0 5730.0 0.53 0.4652 0.8519 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P11 mock treatment 81200.0 -4220.0 -0.39 84400.0 530.0 0.05 -0.2399 -0.6129 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P12 mock treatment 90800.0 5380.0 0.49 84000.0 130.0 0.01 0.3583 0.7241 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P13 mock treatment 87600.0 2180.0 0.2 92400.0 8530.0 0.79 0.7007 0.8591 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P14 mock treatment 84800.0 -622.0 -0.06 91200.0 7330.0 0.68 0.4399 0.6453 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P15 mock treatment 84800.0 -622.0 -0.06 84000.0 130.0 0.01 -0.032 -0.5468 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P16 mock treatment 93600.0 8180.0 0.75 84800.0 930.0 0.09 0.5928 0.783 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P17 mock treatment 83200.0 -2220.0 -0.2 78800.0 -5070.0 -0.47 -0.4769 -0.9304 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P18 mock treatment 93200.0 7780.0 0.72 85600.0 1730.0 0.16 0.6193 0.8446 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P19 mock treatment 92000.0 6580.0 0.61 91600.0 7730.0 0.72 0.9345 0.9965 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P20 mock treatment 84800.0 -622.0 -0.06 77600.0 -6270.0 -0.58 -0.4514 -0.773 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P21 mock treatment 91600.0 6180.0 0.57 91600.0 7730.0 0.72 0.9084 0.9934 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P22 mock treatment 94800.0 9380.0 0.86 92000.0 8130.0 0.75 1.1428 0.9977 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P23 mock treatment 87600.0 2180.0 0.2 91600.0 7730.0 0.72 0.6483 0.8714 1014.0013 LuxReporter(1014.0013) SplicosomeInhibition 1014.0013.Base P24 mock treatment 88000.0 2580.0 0.24 89200.0 5330.0 0.49 0.517 0.9435