ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A01 compound treatment 719200.0 301000.0 3.3 721200.0 303000.0 3.79 5.0136 0.9976 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A02 compound treatment 616400.0 199000.0 2.18 616000.0 198000.0 2.47 3.2874 0.9979 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A03 compound treatment 600400.0 183000.0 2.0 600400.0 182000.0 2.28 3.0255 0.9979 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A04 compound treatment 563600.0 146000.0 1.6 580000.0 162000.0 2.02 2.5602 0.9931 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A05 compound treatment 498800.0 81000.0 0.89 539600.0 121000.0 1.52 1.7012 0.9673 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A06 compound treatment 533600.0 116000.0 1.27 546400.0 128000.0 1.6 2.0308 0.9933 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A07 compound treatment 509200.0 91400.0 1.0 508000.0 89800.0 1.12 1.5023 0.9984 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A08 compound treatment 477200.0 59400.0 0.65 484000.0 65800.0 0.82 1.0423 0.9932 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A09 compound treatment 463600.0 45800.0 0.5 486800.0 68600.0 0.86 0.9618 0.9674 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A10 compound treatment 492000.0 74200.0 0.81 498000.0 79800.0 1.0 1.2807 0.9948 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A11 compound treatment 454000.0 36200.0 0.4 442000.0 23800.0 0.3 0.4913 0.99 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A12 compound treatment 510800.0 93000.0 1.02 479200.0 61000.0 0.76 1.26 0.9899 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A13 mock treatment 528400.0 111000.0 1.21 491200.0 73000.0 0.91 1.5024 0.9903 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A14 mock treatment 522800.0 105000.0 1.15 518800.0 101000.0 1.26 1.7031 0.999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A15 compound treatment 480800.0 63000.0 0.69 485200.0 67000.0 0.84 1.0808 0.9954 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A16 compound treatment 466800.0 49000.0 0.54 469600.0 51400.0 0.64 0.8344 0.996 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A17 compound treatment 478800.0 61000.0 0.67 511600.0 93400.0 1.17 1.2988 0.9649 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A18 compound treatment 521600.0 104000.0 1.14 532800.0 115000.0 1.43 1.8176 0.9934 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A19 compound treatment 544000.0 126000.0 1.38 513600.0 95400.0 1.19 1.8213 0.9973 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A20 compound treatment 495600.0 77800.0 0.85 494400.0 76200.0 0.95 1.2767 0.9984 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A21 compound treatment 599600.0 182000.0 1.99 647200.0 229000.0 2.86 3.4332 0.9842 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A22 compound treatment 537200.0 119000.0 1.31 506800.0 88600.0 1.11 1.7085 0.9966 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A23 compound treatment 560400.0 143000.0 1.56 608000.0 190000.0 2.37 2.783 0.9794 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 A24 compound treatment 667200.0 249000.0 2.73 612800.0 195000.0 2.43 3.6524 0.9983 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B01 compound treatment 556800.0 139000.0 1.52 535200.0 117000.0 1.46 2.1114 0.9998 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B02 compound treatment 483600.0 65800.0 0.72 402800.0 -15400.0 -0.19 0.3738 0.5009 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B03 compound treatment 478000.0 60200.0 0.66 448000.0 29800.0 0.37 0.7301 0.9635 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B04 compound treatment 493600.0 75800.0 0.83 447200.0 29000.0 0.36 0.8438 0.9311 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B05 compound treatment 460400.0 42600.0 0.47 448000.0 29800.0 0.37 0.5939 0.9938 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B06 compound treatment 444400.0 26600.0 0.29 451200.0 33000.0 0.41 0.4983 0.9855 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B07 compound treatment 474800.0 57000.0 0.62 449200.0 31000.0 0.39 0.716 0.9737 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B08 compound treatment 456400.0 38600.0 0.42 469200.0 51000.0 0.64 0.7504 0.9801 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B09 compound treatment 453600.0 35800.0 0.39 448000.0 29800.0 0.37 0.5412 0.9997 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B10 compound treatment 472400.0 54600.0 0.6 494000.0 75800.0 0.95 1.0936 0.9754 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B11 compound treatment 427600.0 9850.0 0.11 411600.0 -6580.0 -0.08 0.018 0.1328 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B12 compound treatment 497600.0 79800.0 0.87 517600.0 99400.0 1.24 1.4974 0.9852 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B13 mock treatment 474400.0 56600.0 0.62 425200.0 7020.0 0.09 0.5006 0.7992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B14 mock treatment 464400.0 46600.0 0.51 450000.0 31800.0 0.4 0.6425 0.9924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B15 compound treatment 436000.0 18200.0 0.2 448400.0 30200.0 0.38 0.4085 0.9556 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B16 compound treatment 419200.0 1450.0 0.02 412800.0 -5380.0 -0.07 -0.0364 -0.5263 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B17 compound treatment 439600.0 21800.0 0.24 434400.0 16200.0 0.2 0.3126 0.9966 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B18 compound treatment 425200.0 7450.0 0.08 432000.0 13800.0 0.17 0.1798 0.9413 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B19 compound treatment 431200.0 13400.0 0.15 439200.0 21000.0 0.26 0.29 0.9625 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B20 compound treatment 438800.0 21000.0 0.23 458800.0 40600.0 0.51 0.5221 0.9361 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B21 compound treatment 479600.0 61800.0 0.68 486000.0 67800.0 0.85 1.0786 0.9938 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B22 compound treatment 506000.0 88200.0 0.97 543200.0 125000.0 1.56 1.7888 0.9732 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B23 compound treatment 492800.0 75000.0 0.82 499600.0 81400.0 1.02 1.301 0.9943 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 B24 compound treatment 516000.0 98200.0 1.08 517600.0 99400.0 1.24 1.6398 0.9974 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C01 compound treatment 538800.0 121000.0 1.33 543200.0 125000.0 1.56 2.0428 0.9966 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C02 compound treatment 517200.0 99400.0 1.09 492800.0 74600.0 0.93 1.4298 0.997 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C03 compound treatment 508400.0 90600.0 0.99 504000.0 85800.0 1.07 1.4607 0.9992 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C04 compound treatment 468400.0 50600.0 0.55 462000.0 43800.0 0.55 0.7796 1.0 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C05 compound treatment 486800.0 69000.0 0.76 508800.0 90600.0 1.13 1.3359 0.9806 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C06 compound treatment 472000.0 54200.0 0.59 466400.0 48200.0 0.6 0.8464 1.0 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C07 compound treatment 475600.0 57800.0 0.63 485600.0 67400.0 0.84 1.0441 0.9901 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C08 compound treatment 460400.0 42600.0 0.47 446800.0 28600.0 0.36 0.5833 0.9914 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C09 compound treatment 394800.0 -23000.0 -0.25 389200.0 -29000.0 -0.36 -0.434 -0.984 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C10 compound treatment 411200.0 -6550.0 -0.07 420000.0 1820.0 0.02 -0.0347 -0.4607 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C11 mock treatment 418000.0 248.0 0.0 417200.0 -984.0 -0.01 -0.0068 -0.5384 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C12 mock treatment 385600.0 -32200.0 -0.35 426400.0 8220.0 0.1 -0.1763 -0.4807 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C13 compound treatment 402800.0 -15000.0 -0.16 405200.0 -13000.0 -0.16 -0.2306 -1.0 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C14 compound treatment 424800.0 7050.0 0.08 415600.0 -2580.0 -0.03 0.0317 0.3791 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C15 mock treatment 421200.0 3450.0 0.04 397600.0 -20600.0 -0.26 -0.1553 -0.597 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C16 mock treatment 418800.0 1050.0 0.01 409600.0 -8580.0 -0.11 -0.0678 -0.628 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C17 compound treatment 417200.0 -552.0 -0.01 409600.0 -8580.0 -0.11 -0.0802 -0.7458 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C18 compound treatment 403600.0 -14200.0 -0.15 407200.0 -11000.0 -0.14 -0.2067 -0.9982 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C19 compound treatment 456400.0 38600.0 0.42 433200.0 15000.0 0.19 0.432 0.9331 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C20 compound treatment 414000.0 -3750.0 -0.04 430800.0 12600.0 0.16 0.0825 0.5061 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C21 compound treatment 505600.0 87800.0 0.96 511600.0 93400.0 1.17 1.5063 0.9953 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C22 compound treatment 458800.0 41000.0 0.45 436400.0 18200.0 0.23 0.4789 0.9504 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C23 compound treatment 557600.0 140000.0 1.53 555200.0 137000.0 1.71 2.2944 0.9984 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 C24 compound treatment 491200.0 73400.0 0.8 518400.0 100000.0 1.25 1.4549 0.977 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D01 compound treatment 483600.0 65800.0 0.72 460000.0 41800.0 0.52 0.8796 0.9876 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D02 compound treatment 470800.0 53000.0 0.58 436000.0 17800.0 0.22 0.5683 0.9135 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D03 compound treatment 413600.0 -4150.0 -0.05 394000.0 -24200.0 -0.3 -0.246 -0.8044 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D04 compound treatment 486000.0 68200.0 0.75 458400.0 40200.0 0.5 0.884 0.9814 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D05 compound treatment 386400.0 -31400.0 -0.34 357600.0 -60600.0 -0.76 -0.7785 -0.9359 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D06 compound treatment 434400.0 16600.0 0.18 411200.0 -6980.0 -0.09 0.0671 0.3321 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D07 compound treatment 414400.0 -3350.0 -0.04 387600.0 -30600.0 -0.38 -0.2964 -0.7714 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D08 compound treatment 430800.0 13000.0 0.14 414800.0 -3380.0 -0.04 0.0711 0.4771 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D09 compound treatment 382800.0 -35000.0 -0.38 412000.0 -6180.0 -0.08 -0.3253 -0.8332 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D10 compound treatment 438800.0 21000.0 0.23 429200.0 11000.0 0.14 0.2604 0.9697 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D11 mock treatment 396400.0 -21400.0 -0.23 380800.0 -37400.0 -0.47 -0.4959 -0.9487 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D12 mock treatment 380400.0 -37400.0 -0.41 403600.0 -14600.0 -0.18 -0.4182 -0.9338 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D13 compound treatment 372800.0 -45000.0 -0.49 409200.0 -8980.0 -0.11 -0.4275 -0.8467 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D14 compound treatment 402800.0 -15000.0 -0.16 405200.0 -13000.0 -0.16 -0.2306 -1.0 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D15 mock treatment 390400.0 -27400.0 -0.3 396800.0 -21400.0 -0.27 -0.4009 -0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D16 mock treatment 407200.0 -10600.0 -0.12 416400.0 -1780.0 -0.02 -0.0975 -0.8284 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D17 compound treatment 377200.0 -40600.0 -0.44 387200.0 -31000.0 -0.39 -0.588 -0.9977 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D18 compound treatment 388800.0 -29000.0 -0.32 421600.0 3420.0 0.04 -0.194 -0.6063 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D19 compound treatment 445200.0 27400.0 0.3 438400.0 20200.0 0.25 0.3913 0.9963 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D20 compound treatment 410000.0 -7750.0 -0.08 381200.0 -37000.0 -0.46 -0.3871 -0.8231 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D21 compound treatment 412400.0 -5350.0 -0.06 384400.0 -33800.0 -0.42 -0.3402 -0.7976 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D22 compound treatment 431200.0 13400.0 0.15 416400.0 -1780.0 -0.02 0.0883 0.5932 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D23 compound treatment 414800.0 -2950.0 -0.03 434000.0 15800.0 0.2 0.117 0.5838 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 D24 compound treatment 476800.0 59000.0 0.65 428400.0 10200.0 0.13 0.5475 0.8308 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E01 mock treatment 532800.0 115000.0 1.26 536800.0 119000.0 1.48 1.9397 0.9967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E02 mock treatment 460000.0 42200.0 0.46 451200.0 33000.0 0.41 0.6191 0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E03 compound treatment 453200.0 35400.0 0.39 479600.0 61400.0 0.77 0.8176 0.95 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E04 compound treatment 447200.0 29400.0 0.32 444800.0 26600.0 0.33 0.4634 0.9999 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E05 compound treatment 441200.0 23400.0 0.26 460400.0 42200.0 0.53 0.5549 0.9451 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E06 compound treatment 408800.0 -8950.0 -0.1 452000.0 33800.0 0.42 0.2297 0.5292 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E07 compound treatment 447200.0 29400.0 0.32 477600.0 59400.0 0.74 0.7534 0.9301 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E08 compound treatment 462800.0 45000.0 0.49 436400.0 18200.0 0.23 0.5099 0.9384 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E09 mock treatment 391600.0 -26200.0 -0.29 416800.0 -1380.0 -0.02 -0.2147 -0.7485 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E10 mock treatment 414000.0 -3750.0 -0.04 380800.0 -37400.0 -0.47 -0.3597 -0.7663 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E11 compound treatment 382800.0 -35000.0 -0.38 374800.0 -43400.0 -0.54 -0.6543 -0.9854 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E12 compound treatment 413600.0 -4150.0 -0.05 393200.0 -25000.0 -0.31 -0.2531 -0.8016 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E13 compound treatment 365200.0 -52600.0 -0.58 377200.0 -41000.0 -0.51 -0.7693 -0.9983 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E14 compound treatment 392000.0 -25800.0 -0.28 388800.0 -29400.0 -0.37 -0.4592 -0.9914 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E15 compound treatment 370800.0 -47000.0 -0.51 355200.0 -63000.0 -0.79 -0.9205 -0.9786 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E16 compound treatment 394400.0 -23400.0 -0.26 387600.0 -30600.0 -0.38 -0.4513 -0.9808 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E17 mock treatment 385200.0 -32600.0 -0.36 388400.0 -29800.0 -0.37 -0.5154 -0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E18 mock treatment 380800.0 -37000.0 -0.4 390000.0 -28200.0 -0.35 -0.5353 -0.9976 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E19 compound treatment 406400.0 -11400.0 -0.12 396400.0 -21800.0 -0.27 -0.2805 -0.9368 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E20 compound treatment 400800.0 -17000.0 -0.19 394800.0 -23400.0 -0.29 -0.338 -0.9759 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E21 compound treatment 492800.0 75000.0 0.82 491600.0 73400.0 0.92 1.2303 0.9985 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E22 compound treatment 420800.0 3050.0 0.03 430800.0 12600.0 0.16 0.1352 0.8381 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E23 compound treatment 468800.0 51000.0 0.56 478800.0 60600.0 0.76 0.9313 0.9888 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 E24 compound treatment 459200.0 41400.0 0.45 507200.0 89000.0 1.11 1.1081 0.9217 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F01 mock treatment 502800.0 85000.0 0.93 484800.0 66600.0 0.83 1.2476 0.9985 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F02 mock treatment 426800.0 9050.0 0.1 443600.0 25400.0 0.32 0.2948 0.8855 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F03 compound treatment 421600.0 3850.0 0.04 383200.0 -35000.0 -0.44 -0.2796 -0.6361 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F04 compound treatment 408400.0 -9350.0 -0.1 426800.0 8620.0 0.11 0.0038 0.0255 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F05 compound treatment 451200.0 33400.0 0.37 434800.0 16600.0 0.21 0.4059 0.964 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F06 compound treatment 402800.0 -15000.0 -0.16 390400.0 -27800.0 -0.35 -0.3615 -0.941 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F07 compound treatment 422800.0 5050.0 0.06 455200.0 37000.0 0.46 0.3664 0.7859 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F08 compound treatment 453200.0 35400.0 0.39 407600.0 -10600.0 -0.13 0.1808 0.441 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F09 mock treatment 414400.0 -3350.0 -0.04 394000.0 -24200.0 -0.3 -0.2398 -0.7871 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F10 mock treatment 372800.0 -45000.0 -0.49 405600.0 -12600.0 -0.16 -0.4593 -0.8889 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F11 compound treatment 403200.0 -14600.0 -0.16 415600.0 -2580.0 -0.03 -0.1355 -0.8336 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F12 compound treatment 459200.0 41400.0 0.45 437600.0 19400.0 0.24 0.4926 0.9571 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F13 compound treatment 422000.0 4250.0 0.05 412000.0 -6180.0 -0.08 -0.0218 -0.2416 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F14 compound treatment 384000.0 -33800.0 -0.37 408800.0 -9380.0 -0.12 -0.3443 -0.888 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F15 compound treatment 417200.0 -552.0 -0.01 411600.0 -6580.0 -0.08 -0.0625 -0.757 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F16 compound treatment 399200.0 -18600.0 -0.2 386800.0 -31400.0 -0.39 -0.4212 -0.953 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F17 mock treatment 408800.0 -8950.0 -0.1 376000.0 -42200.0 -0.53 -0.4424 -0.8244 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F18 mock treatment 389200.0 -28600.0 -0.31 388000.0 -30200.0 -0.38 -0.488 -0.9956 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F19 compound treatment 422400.0 4650.0 0.05 405200.0 -13000.0 -0.16 -0.0788 -0.4633 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F20 compound treatment 402800.0 -15000.0 -0.16 412800.0 -5380.0 -0.07 -0.1634 -0.9229 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F21 compound treatment 386800.0 -31000.0 -0.34 452800.0 34600.0 0.43 0.0665 0.1209 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F22 compound treatment 441600.0 23800.0 0.26 419600.0 1420.0 0.02 0.1972 0.7533 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F23 compound treatment 438400.0 20600.0 0.23 438400.0 20200.0 0.25 0.3386 0.9984 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 F24 compound treatment 538000.0 120000.0 1.32 530400.0 112000.0 1.4 1.9234 0.9995 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G01 compound treatment 518800.0 101000.0 1.11 502800.0 84600.0 1.06 1.5306 0.9998 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G02 compound treatment 516800.0 99000.0 1.08 484400.0 66200.0 0.83 1.3524 0.9911 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G03 mock treatment 403200.0 -14600.0 -0.16 403200.0 -15000.0 -0.19 -0.2452 -0.9967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G04 mock treatment 385600.0 -32200.0 -0.35 394800.0 -23400.0 -0.29 -0.4557 -0.9958 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G05 compound treatment 423200.0 5450.0 0.06 434800.0 16600.0 0.21 0.1891 0.8748 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G06 compound treatment 431200.0 13400.0 0.15 442000.0 23800.0 0.3 0.3147 0.9472 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G07 compound treatment 370400.0 -47400.0 -0.52 374800.0 -43400.0 -0.54 -0.7503 -0.9997 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G08 compound treatment 414000.0 -3750.0 -0.04 419600.0 1420.0 0.02 -0.0165 -0.3695 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G09 compound treatment 339600.0 -78200.0 -0.86 361200.0 -57000.0 -0.71 -1.109 -0.9959 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G10 compound treatment 370000.0 -47800.0 -0.52 384000.0 -34200.0 -0.43 -0.672 -0.995 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G11 compound treatment 331200.0 -86600.0 -0.95 335200.0 -83000.0 -1.04 -1.404 -0.999 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G12 compound treatment 378000.0 -39800.0 -0.44 376000.0 -42200.0 -0.53 -0.6808 -0.9954 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G13 compound treatment 365600.0 -52200.0 -0.57 367600.0 -50600.0 -0.63 -0.8511 -0.9987 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G14 compound treatment 383200.0 -34600.0 -0.38 378400.0 -39800.0 -0.5 -0.6193 -0.9909 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G15 compound treatment 381200.0 -36600.0 -0.4 375200.0 -43000.0 -0.54 -0.6631 -0.9894 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G16 compound treatment 354800.0 -63000.0 -0.69 345200.0 -73000.0 -0.91 -1.1328 -0.9904 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G17 compound treatment 360400.0 -57400.0 -0.63 345200.0 -73000.0 -0.91 -1.0895 -0.9833 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G18 compound treatment 366800.0 -51000.0 -0.56 350000.0 -68200.0 -0.85 -0.9975 -0.9788 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G19 mock treatment 373600.0 -44200.0 -0.48 373200.0 -45000.0 -0.56 -0.7397 -0.9971 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G20 mock treatment 390800.0 -27000.0 -0.3 400000.0 -18200.0 -0.23 -0.3695 -0.9917 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G21 compound treatment 515600.0 97800.0 1.07 539600.0 121000.0 1.52 1.8313 0.9854 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G22 compound treatment 416400.0 -1350.0 -0.01 414800.0 -3380.0 -0.04 -0.0404 -0.901 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G23 compound treatment 410400.0 -7350.0 -0.08 426400.0 8220.0 0.1 0.0157 0.1205 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 G24 compound treatment 468400.0 50600.0 0.55 242000.0 -176000.0 -2.2 -1.1659 -0.5131 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H01 compound treatment 519600.0 102000.0 1.12 469600.0 51400.0 0.64 1.2432 0.9658 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H02 compound treatment 429600.0 11800.0 0.13 421600.0 3420.0 0.04 0.1219 0.8928 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H03 mock treatment 395200.0 -22600.0 -0.25 388400.0 -29800.0 -0.37 -0.438 -0.9801 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H04 mock treatment 404400.0 -13400.0 -0.15 408800.0 -9380.0 -0.12 -0.1864 -0.9941 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H05 compound treatment 385600.0 -32200.0 -0.35 397200.0 -21000.0 -0.26 -0.4345 -0.9895 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H06 compound treatment 413600.0 -4150.0 -0.05 388400.0 -29800.0 -0.37 -0.2955 -0.7876 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H07 compound treatment 383200.0 -34600.0 -0.38 376800.0 -41400.0 -0.52 -0.6335 -0.9881 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H08 compound treatment 386800.0 -31000.0 -0.34 415600.0 -2580.0 -0.03 -0.2625 -0.771 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H09 compound treatment 364400.0 -53400.0 -0.58 366000.0 -52200.0 -0.65 -0.8746 -0.9985 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H10 compound treatment 401200.0 -16600.0 -0.18 434400.0 16200.0 0.2 0.0152 0.0561 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H11 compound treatment 422800.0 5050.0 0.06 397200.0 -21000.0 -0.26 -0.1465 -0.5462 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H12 compound treatment 457200.0 39400.0 0.43 462400.0 44200.0 0.55 0.6964 0.9925 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H13 compound treatment 364400.0 -53400.0 -0.58 372400.0 -45800.0 -0.57 -0.818 -0.9999 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H14 compound treatment 343600.0 -74200.0 -0.81 380800.0 -37400.0 -0.47 -0.9047 -0.9656 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H15 compound treatment 384400.0 -33400.0 -0.37 378400.0 -39800.0 -0.5 -0.6101 -0.9884 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H16 compound treatment 366000.0 -51800.0 -0.57 404800.0 -13400.0 -0.17 -0.519 -0.8785 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H17 compound treatment 392800.0 -25000.0 -0.27 380800.0 -37400.0 -0.47 -0.5238 -0.9673 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H18 compound treatment 398800.0 -19000.0 -0.21 371200.0 -47000.0 -0.59 -0.5622 -0.9022 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H19 mock treatment 377600.0 -40200.0 -0.44 395200.0 -23000.0 -0.29 -0.5141 -0.9788 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H20 mock treatment 377200.0 -40600.0 -0.44 412800.0 -5380.0 -0.07 -0.3616 -0.8051 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H21 compound treatment 372400.0 -45400.0 -0.5 378800.0 -39400.0 -0.49 -0.6994 -1.0 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H22 compound treatment 430000.0 12200.0 0.13 433200.0 15000.0 0.19 0.2276 0.9864 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H23 compound treatment 467600.0 49800.0 0.55 420000.0 1820.0 0.02 0.402 0.7359 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 H24 compound treatment 484800.0 67000.0 0.73 462400.0 44200.0 0.55 0.9101 0.9902 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I01 compound treatment 553600.0 136000.0 1.49 526000.0 108000.0 1.35 2.0052 0.9988 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I02 compound treatment 461200.0 43400.0 0.48 466800.0 48600.0 0.61 0.7663 0.9926 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I03 compound treatment 413200.0 -4550.0 -0.05 400400.0 -17800.0 -0.22 -0.1925 -0.8446 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I04 compound treatment 422400.0 4650.0 0.05 432800.0 14600.0 0.18 0.1652 0.8708 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I05 mock treatment 392800.0 -25000.0 -0.27 404800.0 -13400.0 -0.17 -0.3116 -0.9723 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I06 mock treatment 408400.0 -9350.0 -0.1 370000.0 -48200.0 -0.6 -0.4985 -0.8156 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I07 compound treatment 364400.0 -53400.0 -0.58 369200.0 -49000.0 -0.61 -0.8463 -0.9997 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I08 compound treatment 400800.0 -17000.0 -0.19 408800.0 -9380.0 -0.12 -0.2142 -0.9756 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I09 compound treatment 384800.0 -33000.0 -0.36 364400.0 -53800.0 -0.67 -0.7308 -0.9574 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I10 compound treatment 376800.0 -41000.0 -0.45 382800.0 -35400.0 -0.44 -0.63 -1.0 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I11 compound treatment 340000.0 -77800.0 -0.85 374400.0 -43800.0 -0.55 -0.9892 -0.9772 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I12 compound treatment 368000.0 -49800.0 -0.54 379600.0 -38600.0 -0.48 -0.7264 -0.9982 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I13 compound treatment 336800.0 -81000.0 -0.89 357200.0 -61000.0 -0.76 -1.1661 -0.9972 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I14 compound treatment 356000.0 -61800.0 -0.68 367600.0 -50600.0 -0.63 -0.9254 -0.9994 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I15 compound treatment 335600.0 -82200.0 -0.9 358000.0 -60200.0 -0.75 -1.1683 -0.9961 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I16 compound treatment 370000.0 -47800.0 -0.52 370000.0 -48200.0 -0.6 -0.7958 -0.9975 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I17 compound treatment 400000.0 -17800.0 -0.19 388000.0 -30200.0 -0.38 -0.4044 -0.9524 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I18 compound treatment 400400.0 -17400.0 -0.19 361200.0 -57000.0 -0.71 -0.6383 -0.8654 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I19 compound treatment 481600.0 63800.0 0.7 444400.0 26200.0 0.33 0.7262 0.9404 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I20 compound treatment 399600.0 -18200.0 -0.2 402400.0 -15800.0 -0.2 -0.2801 -1.0 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I21 mock treatment 392000.0 -25800.0 -0.28 421200.0 3020.0 0.04 -0.1727 -0.6071 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I22 mock treatment 392800.0 -25000.0 -0.27 410000.0 -8180.0 -0.1 -0.2656 -0.9102 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I23 compound treatment 432400.0 14600.0 0.16 442000.0 23800.0 0.3 0.324 0.9578 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 I24 compound treatment 471600.0 53800.0 0.59 513200.0 95000.0 1.19 1.2572 0.9477 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J01 compound treatment 476800.0 59000.0 0.65 466000.0 47800.0 0.6 0.88 0.9992 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J02 compound treatment 428800.0 11000.0 0.12 435600.0 17400.0 0.22 0.2395 0.9615 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J03 compound treatment 417200.0 -552.0 -0.01 398800.0 -19400.0 -0.24 -0.1757 -0.7245 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J04 compound treatment 444000.0 26200.0 0.29 410800.0 -7380.0 -0.09 0.1379 0.4569 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J05 mock treatment 427600.0 9850.0 0.11 401600.0 -16600.0 -0.21 -0.0704 -0.3012 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J06 mock treatment 413200.0 -4550.0 -0.05 421600.0 3420.0 0.04 -0.005 -0.0768 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J07 compound treatment 381200.0 -36600.0 -0.4 375600.0 -42600.0 -0.53 -0.6596 -0.9901 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J08 compound treatment 368800.0 -49000.0 -0.54 413600.0 -4580.0 -0.06 -0.4195 -0.7783 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J09 compound treatment 380800.0 -37000.0 -0.4 366000.0 -52200.0 -0.65 -0.7476 -0.9736 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J10 compound treatment 408000.0 -9750.0 -0.11 417200.0 -984.0 -0.01 -0.0842 -0.7834 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J11 compound treatment 402400.0 -15400.0 -0.17 391200.0 -27000.0 -0.34 -0.3575 -0.9482 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J12 compound treatment 480000.0 62200.0 0.68 490400.0 72200.0 0.9 1.1206 0.9904 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J13 compound treatment 427200.0 9450.0 0.1 471200.0 53000.0 0.66 0.542 0.8077 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J14 compound treatment 386400.0 -31400.0 -0.34 390800.0 -27400.0 -0.34 -0.4849 -1.0 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J15 compound treatment 394000.0 -23800.0 -0.26 387600.0 -30600.0 -0.38 -0.4544 -0.9823 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J16 compound treatment 362000.0 -55800.0 -0.61 360800.0 -57400.0 -0.72 -0.9391 -0.9968 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J17 compound treatment 348800.0 -69000.0 -0.75 382000.0 -36200.0 -0.45 -0.8538 -0.97 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J18 compound treatment 381600.0 -36200.0 -0.4 399200.0 -19000.0 -0.24 -0.4478 -0.9701 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J19 compound treatment 368400.0 -49400.0 -0.54 371600.0 -46600.0 -0.58 -0.7941 -0.9993 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J20 compound treatment 410400.0 -7350.0 -0.08 411600.0 -6580.0 -0.08 -0.1152 -0.9999 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J21 mock treatment 401600.0 -16200.0 -0.18 407200.0 -11000.0 -0.14 -0.2222 -0.9922 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J22 mock treatment 390800.0 -27000.0 -0.3 408400.0 -9780.0 -0.12 -0.2952 -0.924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J23 compound treatment 469200.0 51400.0 0.56 409600.0 -8580.0 -0.11 0.3224 0.5622 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 J24 compound treatment 480800.0 63000.0 0.69 517600.0 99400.0 1.24 1.3673 0.9615 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K01 compound treatment 534000.0 116000.0 1.27 550000.0 132000.0 1.65 2.0657 0.9918 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K02 compound treatment 493600.0 75800.0 0.83 490000.0 71800.0 0.9 1.2223 0.9992 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K03 compound treatment 456800.0 39000.0 0.43 456400.0 38200.0 0.48 0.6403 0.9985 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K04 compound treatment 452000.0 34200.0 0.37 426000.0 7820.0 0.1 0.3343 0.8626 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K05 compound treatment 413600.0 -4150.0 -0.05 408800.0 -9380.0 -0.12 -0.1151 -0.9148 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K06 compound treatment 422000.0 4250.0 0.05 420800.0 2620.0 0.03 0.056 0.9852 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K07 mock treatment 375600.0 -42200.0 -0.46 371600.0 -46600.0 -0.58 -0.7383 -0.9933 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K08 mock treatment 382400.0 -35400.0 -0.39 379200.0 -39000.0 -0.49 -0.6185 -0.9935 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K09 compound treatment 348000.0 -69800.0 -0.76 350000.0 -68200.0 -0.85 -1.143 -0.9985 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K10 compound treatment 412800.0 -4950.0 -0.05 389600.0 -28600.0 -0.36 -0.2911 -0.8052 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K11 compound treatment 365600.0 -52200.0 -0.57 353200.0 -65000.0 -0.81 -0.9785 -0.9851 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K12 compound treatment 376800.0 -41000.0 -0.45 371200.0 -47000.0 -0.59 -0.7326 -0.9911 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K13 compound treatment 350000.0 -67800.0 -0.74 354000.0 -64200.0 -0.8 -1.0922 -0.9992 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K14 compound treatment 401600.0 -16200.0 -0.18 405200.0 -13000.0 -0.16 -0.2399 -0.9991 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K15 mock treatment 389600.0 -28200.0 -0.31 393200.0 -25000.0 -0.31 -0.4389 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K16 mock treatment 360400.0 -57400.0 -0.63 372000.0 -46200.0 -0.58 -0.8525 -0.9991 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K17 compound treatment 374400.0 -43400.0 -0.47 366000.0 -52200.0 -0.65 -0.7971 -0.9878 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K18 compound treatment 360800.0 -57000.0 -0.62 400400.0 -17800.0 -0.22 -0.5982 -0.9036 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K19 compound treatment 483200.0 65400.0 0.72 460400.0 42200.0 0.53 0.8801 0.9887 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K20 compound treatment 432800.0 15000.0 0.16 381600.0 -36600.0 -0.46 -0.207 -0.4257 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K21 compound treatment 502000.0 84200.0 0.92 478800.0 60600.0 0.76 1.1883 0.9953 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K22 compound treatment 428000.0 10200.0 0.11 398800.0 -19400.0 -0.24 -0.0921 -0.3447 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K23 mock treatment 456000.0 38200.0 0.42 446000.0 27800.0 0.35 0.5421 0.9957 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 K24 mock treatment 485600.0 67800.0 0.74 515200.0 97000.0 1.21 1.3832 0.9723 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L01 compound treatment 514800.0 97000.0 1.06 505200.0 87000.0 1.09 1.5209 0.9999 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L02 compound treatment 456800.0 39000.0 0.43 432800.0 14600.0 0.18 0.4316 0.9282 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L03 compound treatment 437200.0 19400.0 0.21 446400.0 28200.0 0.35 0.4001 0.9708 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L04 compound treatment 431200.0 13400.0 0.15 429600.0 11400.0 0.14 0.2051 0.9999 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L05 compound treatment 434400.0 16600.0 0.18 416800.0 -1380.0 -0.02 0.1167 0.6371 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L06 compound treatment 428400.0 10600.0 0.12 426400.0 8220.0 0.1 0.1551 0.998 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L07 mock treatment 392400.0 -25400.0 -0.28 440400.0 22200.0 0.28 2.0E-4 4.0E-4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L08 mock treatment 419600.0 1850.0 0.02 403600.0 -14600.0 -0.18 -0.1147 -0.6248 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L09 compound treatment 414400.0 -3350.0 -0.04 414400.0 -3780.0 -0.05 -0.0594 -0.9921 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L10 compound treatment 456400.0 38600.0 0.42 454800.0 36600.0 0.46 0.623 0.9992 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L11 compound treatment 408800.0 -8950.0 -0.1 402400.0 -15800.0 -0.2 -0.2089 -0.9478 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L12 compound treatment 399200.0 -18600.0 -0.2 388000.0 -30200.0 -0.38 -0.4106 -0.9578 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L13 compound treatment 432800.0 15000.0 0.16 416400.0 -1780.0 -0.02 0.1007 0.6058 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L14 compound treatment 416800.0 -952.0 -0.01 406000.0 -12200.0 -0.15 -0.1151 -0.7537 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L15 mock treatment 400000.0 -17800.0 -0.19 430800.0 12600.0 0.16 -0.0259 -0.1034 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L16 mock treatment 392800.0 -25000.0 -0.27 403600.0 -14600.0 -0.18 -0.3222 -0.9807 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L17 compound treatment 394000.0 -23800.0 -0.26 385600.0 -32600.0 -0.41 -0.4721 -0.9765 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L18 compound treatment 383600.0 -34200.0 -0.37 441200.0 23000.0 0.29 -0.0609 -0.129 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L19 compound treatment 392000.0 -25800.0 -0.28 399600.0 -18600.0 -0.23 -0.3637 -0.9954 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L20 compound treatment 394800.0 -23000.0 -0.25 383200.0 -35000.0 -0.44 -0.4871 -0.9654 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L21 compound treatment 455600.0 37800.0 0.41 425600.0 7420.0 0.09 0.3586 0.8445 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L22 compound treatment 426800.0 9050.0 0.1 429200.0 11000.0 0.14 0.1675 0.9869 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L23 mock treatment 402000.0 -15800.0 -0.17 447200.0 29000.0 0.36 0.1346 0.3351 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 L24 mock treatment 536000.0 118000.0 1.29 488800.0 70600.0 0.88 1.54 0.9826 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M01 compound treatment 626800.0 209000.0 2.29 596000.0 178000.0 2.22 3.191 0.9999 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M02 compound treatment 487200.0 69400.0 0.76 470000.0 51800.0 0.65 0.9959 0.9968 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M03 compound treatment 488800.0 71000.0 0.78 498800.0 80600.0 1.01 1.263 0.9918 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M04 compound treatment 443200.0 25400.0 0.28 424800.0 6620.0 0.08 0.2555 0.8791 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M05 compound treatment 456000.0 38200.0 0.42 448400.0 30200.0 0.38 0.5633 0.9987 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M06 compound treatment 430400.0 12600.0 0.14 428000.0 9820.0 0.12 0.1847 0.9982 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M07 compound treatment 388000.0 -29800.0 -0.33 372000.0 -46200.0 -0.58 -0.6388 -0.9633 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M08 compound treatment 420000.0 2250.0 0.02 388000.0 -30200.0 -0.38 -0.2495 -0.6596 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M09 mock treatment 405600.0 -12200.0 -0.13 395200.0 -23000.0 -0.29 -0.2973 -0.9387 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M10 mock treatment 383200.0 -34600.0 -0.38 400400.0 -17800.0 -0.22 -0.4248 -0.9679 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M11 compound treatment 441600.0 23800.0 0.26 466000.0 47800.0 0.6 0.6075 0.931 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M12 compound treatment 401600.0 -16200.0 -0.18 412800.0 -5380.0 -0.07 -0.1727 -0.9124 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M13 mock treatment 398800.0 -19000.0 -0.21 355200.0 -63000.0 -0.79 -0.7037 -0.8639 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M14 mock treatment 397600.0 -20200.0 -0.22 364000.0 -54200.0 -0.68 -0.6352 -0.8913 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M15 compound treatment 398000.0 -19800.0 -0.22 422000.0 3820.0 0.05 -0.1192 -0.5381 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M16 compound treatment 390400.0 -27400.0 -0.3 397600.0 -20600.0 -0.26 -0.3938 -0.9972 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M17 compound treatment 422800.0 5050.0 0.06 415600.0 -2580.0 -0.03 0.0162 0.2535 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M18 compound treatment 379200.0 -38600.0 -0.42 382000.0 -36200.0 -0.45 -0.6185 -0.9994 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M19 compound treatment 505200.0 87400.0 0.96 508800.0 90600.0 1.13 1.4784 0.9965 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M20 compound treatment 387600.0 -30200.0 -0.33 392400.0 -25800.0 -0.32 -0.4615 -0.9999 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M21 compound treatment 536000.0 118000.0 1.29 512400.0 94200.0 1.18 1.7487 0.9989 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M22 compound treatment 434800.0 17000.0 0.19 414800.0 -3380.0 -0.04 0.1021 0.5332 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M23 compound treatment 467600.0 49800.0 0.55 477200.0 59000.0 0.74 0.9078 0.989 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 M24 compound treatment 529200.0 111000.0 1.22 516800.0 98600.0 1.23 1.735 1.0 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N01 compound treatment 546000.0 128000.0 1.4 543600.0 125000.0 1.57 2.102 0.9985 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N02 compound treatment 440000.0 22200.0 0.24 430800.0 12600.0 0.16 0.2838 0.9779 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N03 compound treatment 482400.0 64600.0 0.71 468000.0 49800.0 0.62 0.9411 0.998 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N04 compound treatment 447600.0 29800.0 0.33 482000.0 63800.0 0.8 0.7954 0.9223 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N05 compound treatment 422000.0 4250.0 0.05 411200.0 -6980.0 -0.09 -0.0289 -0.2918 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N06 compound treatment 438400.0 20600.0 0.23 453600.0 35400.0 0.44 0.4731 0.9513 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N07 compound treatment 402000.0 -15800.0 -0.17 411200.0 -6980.0 -0.09 -0.1837 -0.9503 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N08 compound treatment 456000.0 38200.0 0.42 436000.0 17800.0 0.22 0.4537 0.9564 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N09 mock treatment 416800.0 -952.0 -0.01 395600.0 -22600.0 -0.28 -0.2071 -0.7327 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N10 mock treatment 408000.0 -9750.0 -0.11 425600.0 7420.0 0.09 -0.0099 -0.0702 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N11 compound treatment 437600.0 19800.0 0.22 437200.0 19000.0 0.24 0.3218 0.999 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N12 compound treatment 431600.0 13800.0 0.15 401200.0 -17000.0 -0.21 -0.043 -0.1647 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N13 mock treatment 435600.0 17800.0 0.2 442000.0 23800.0 0.3 0.3488 0.9791 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N14 mock treatment 430000.0 12200.0 0.13 450400.0 32200.0 0.4 0.3797 0.8942 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N15 compound treatment 444800.0 27000.0 0.3 458000.0 39800.0 0.5 0.5615 0.9692 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N16 compound treatment 412800.0 -4950.0 -0.05 406400.0 -11800.0 -0.15 -0.1426 -0.9078 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N17 compound treatment 426800.0 9050.0 0.1 422000.0 3820.0 0.05 0.1038 0.9439 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N18 compound treatment 422400.0 4650.0 0.05 451600.0 33400.0 0.42 0.3315 0.7874 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N19 compound treatment 466800.0 49000.0 0.54 427200.0 9020.0 0.11 0.4595 0.8373 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N20 compound treatment 415600.0 -2150.0 -0.02 428800.0 10600.0 0.13 0.0772 0.5726 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N21 compound treatment 383600.0 -34200.0 -0.37 414000.0 -4180.0 -0.05 -0.3014 -0.7983 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N22 compound treatment 465200.0 47400.0 0.52 478400.0 60200.0 0.75 0.8999 0.9836 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N23 compound treatment 481200.0 63400.0 0.69 484800.0 66600.0 0.83 1.0803 0.9959 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 N24 compound treatment 582000.0 164000.0 1.8 540000.0 122000.0 1.52 2.3489 0.9966 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O01 compound treatment 582800.0 165000.0 1.81 542400.0 124000.0 1.55 2.3763 0.9972 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O02 compound treatment 600800.0 183000.0 2.0 573200.0 155000.0 1.94 2.7881 0.9999 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O03 compound treatment 516400.0 98600.0 1.08 506000.0 87800.0 1.1 1.5404 1.0 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O04 compound treatment 496400.0 78600.0 0.86 514800.0 96600.0 1.21 1.4633 0.9862 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O05 compound treatment 432000.0 14200.0 0.16 443600.0 25400.0 0.32 0.3351 0.9463 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O06 compound treatment 521600.0 104000.0 1.14 516800.0 98600.0 1.23 1.6761 0.9992 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O07 compound treatment 444000.0 26200.0 0.29 420400.0 2220.0 0.03 0.2228 0.7717 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O08 compound treatment 478800.0 61000.0 0.67 464000.0 45800.0 0.57 0.8778 0.9971 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O09 compound treatment 414800.0 -2950.0 -0.03 411600.0 -6580.0 -0.08 -0.0811 -0.9166 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O10 compound treatment 464400.0 46600.0 0.51 477200.0 59000.0 0.74 0.8831 0.9838 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O11 mock treatment 455200.0 37400.0 0.41 481200.0 63000.0 0.79 0.8472 0.9536 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O12 mock treatment 463600.0 45800.0 0.5 440400.0 22200.0 0.28 0.5514 0.9611 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O13 compound treatment 426400.0 8650.0 0.09 453200.0 35000.0 0.44 0.3766 0.8406 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O14 compound treatment 448800.0 31000.0 0.34 434000.0 15800.0 0.2 0.3802 0.9668 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O15 compound treatment 422000.0 4250.0 0.05 413200.0 -4980.0 -0.06 -0.0112 -0.1439 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O16 compound treatment 438000.0 20200.0 0.22 459200.0 41000.0 0.51 0.5195 0.9296 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O17 compound treatment 442800.0 25000.0 0.27 444800.0 26600.0 0.33 0.4293 0.9954 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O18 compound treatment 504800.0 87000.0 0.95 462800.0 44600.0 0.56 1.0685 0.9675 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O19 compound treatment 525600.0 108000.0 1.18 550400.0 132000.0 1.65 2.0042 0.9864 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O20 compound treatment 455200.0 37400.0 0.41 446400.0 28200.0 0.35 0.5395 0.9972 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O21 compound treatment 632400.0 215000.0 2.35 561600.0 143000.0 1.79 2.9302 0.9911 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O22 compound treatment 475600.0 57800.0 0.63 463600.0 45400.0 0.57 0.8495 0.9985 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O23 compound treatment 496800.0 79000.0 0.87 499200.0 81000.0 1.01 1.3285 0.9969 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 O24 compound treatment 592000.0 174000.0 1.91 553600.0 135000.0 1.69 2.5466 0.9982 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P01 compound treatment 578400.0 161000.0 1.76 574400.0 156000.0 1.95 2.6253 0.9986 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P02 compound treatment 558400.0 141000.0 1.54 549200.0 131000.0 1.64 2.2476 0.9995 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P03 compound treatment 500400.0 82600.0 0.9 505200.0 87000.0 1.09 1.4094 0.9958 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P04 compound treatment 532400.0 115000.0 1.26 511200.0 93000.0 1.16 1.7102 0.9993 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P05 compound treatment 524400.0 107000.0 1.17 531200.0 113000.0 1.41 1.8251 0.9955 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P06 compound treatment 552000.0 134000.0 1.47 544800.0 127000.0 1.58 2.1591 0.9993 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P07 compound treatment 461600.0 43800.0 0.48 476400.0 58200.0 0.73 0.8543 0.9796 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P08 compound treatment 593200.0 175000.0 1.92 591200.0 173000.0 2.16 2.8884 0.9982 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P09 compound treatment 510800.0 93000.0 1.02 521200.0 103000.0 1.29 1.6314 0.9932 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P10 compound treatment 561600.0 144000.0 1.58 570800.0 153000.0 1.91 2.4634 0.9954 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P11 mock treatment 556400.0 139000.0 1.52 522800.0 105000.0 1.31 1.9986 0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P12 mock treatment 517600.0 99800.0 1.09 507200.0 89000.0 1.11 1.5603 1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P13 compound treatment 515600.0 97800.0 1.07 546400.0 128000.0 1.6 1.8914 0.9808 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P14 compound treatment 490000.0 72200.0 0.79 491200.0 73000.0 0.91 1.2051 0.9974 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P15 compound treatment 529200.0 111000.0 1.22 538800.0 121000.0 1.51 1.9295 0.9945 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P16 compound treatment 482000.0 64200.0 0.7 473600.0 55400.0 0.69 0.9875 1.0 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P17 compound treatment 479200.0 61400.0 0.67 484800.0 66600.0 0.83 1.0649 0.9944 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P18 compound treatment 488400.0 70600.0 0.77 486000.0 67800.0 0.85 1.1467 0.9989 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P19 compound treatment 484800.0 67000.0 0.73 470400.0 52200.0 0.65 0.9809 0.9983 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P20 compound treatment 546000.0 128000.0 1.4 495600.0 77400.0 0.97 1.6776 0.9835 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P21 compound treatment 546400.0 129000.0 1.41 524800.0 107000.0 1.33 1.9389 0.9996 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P22 compound treatment 708000.0 290000.0 3.18 684000.0 266000.0 3.32 4.5979 0.9997 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P23 compound treatment 523200.0 105000.0 1.15 566000.0 148000.0 1.85 2.1236 0.9743 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2100 P24 compound treatment 860800.0 443000.0 4.85 823200.0 405000.0 5.07 7.0119 0.9998 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A01 compound treatment 651200.0 240000.0 2.63 610400.0 183000.0 2.29 3.4764 0.9975 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A02 compound treatment 520400.0 110000.0 1.2 569200.0 142000.0 1.77 2.0994 0.982 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A03 compound treatment 514000.0 103000.0 1.13 542400.0 115000.0 1.43 1.8128 0.993 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A04 compound treatment 499600.0 88700.0 0.97 498800.0 71100.0 0.89 1.3157 0.999 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A05 compound treatment 472800.0 61900.0 0.68 443600.0 15900.0 0.2 0.6201 0.8777 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A06 compound treatment 487200.0 76300.0 0.84 458000.0 30300.0 0.38 0.8589 0.9361 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A07 compound treatment 463200.0 52300.0 0.57 491200.0 63500.0 0.79 0.9667 0.9871 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A08 compound treatment 489200.0 78300.0 0.86 453600.0 25900.0 0.32 0.8355 0.9114 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A09 compound treatment 486000.0 75100.0 0.82 486400.0 58700.0 0.73 1.1008 0.9984 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A10 compound treatment 485600.0 74700.0 0.82 476400.0 48700.0 0.61 1.0093 0.9895 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A11 compound treatment 474000.0 63100.0 0.69 475200.0 47500.0 0.59 0.9088 0.9972 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A12 compound treatment 489600.0 78700.0 0.86 481200.0 53500.0 0.67 1.0827 0.9922 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A13 mock treatment 477200.0 66300.0 0.73 478000.0 50300.0 0.63 0.9584 0.9975 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A14 mock treatment 472800.0 61900.0 0.68 514000.0 86300.0 1.08 1.2427 0.9749 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A15 compound treatment 464400.0 53500.0 0.59 493200.0 65500.0 0.82 0.9937 0.9865 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A16 compound treatment 466000.0 55100.0 0.6 492000.0 64300.0 0.8 0.9955 0.99 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A17 compound treatment 495600.0 84700.0 0.93 497600.0 69900.0 0.87 1.2742 0.9996 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A18 compound treatment 505600.0 94700.0 1.04 464800.0 37100.0 0.46 1.0615 0.9343 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A19 compound treatment 512000.0 101000.0 1.11 425600.0 -2080.0 -0.03 0.7644 0.6903 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A20 compound treatment 500800.0 89900.0 0.98 498400.0 70700.0 0.88 1.3215 0.9986 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A21 compound treatment 520400.0 110000.0 1.2 504000.0 76300.0 0.95 1.5228 0.9936 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A22 compound treatment 525200.0 114000.0 1.25 513200.0 85500.0 1.07 1.6413 0.9969 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A23 compound treatment 555200.0 144000.0 1.58 555600.0 128000.0 1.6 2.2485 1.0 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 A24 compound treatment 585600.0 175000.0 1.91 686400.0 259000.0 3.24 3.6406 0.9686 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B01 compound treatment 546800.0 136000.0 1.49 554000.0 126000.0 1.58 2.1693 0.9996 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B02 compound treatment 471200.0 60300.0 0.66 486800.0 59100.0 0.74 0.9897 0.9984 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B03 compound treatment 487200.0 76300.0 0.84 481200.0 53500.0 0.67 1.0641 0.994 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B04 compound treatment 496000.0 85100.0 0.93 480000.0 52300.0 0.65 1.1216 0.985 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B05 compound treatment 476400.0 65500.0 0.72 482800.0 55100.0 0.69 0.9946 0.9998 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B06 compound treatment 459600.0 48700.0 0.53 483200.0 55500.0 0.69 0.8681 0.9915 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B07 compound treatment 488000.0 77100.0 0.84 468800.0 41100.0 0.51 0.9606 0.9717 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B08 compound treatment 467600.0 56700.0 0.62 455200.0 27500.0 0.34 0.6824 0.9612 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B09 compound treatment 462400.0 51500.0 0.56 478800.0 51100.0 0.64 0.8509 0.998 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B10 compound treatment 464000.0 53100.0 0.58 467600.0 39900.0 0.5 0.7642 0.9971 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B11 compound treatment 490400.0 79500.0 0.87 462000.0 34300.0 0.43 0.9191 0.9469 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B12 compound treatment 453200.0 42300.0 0.46 455600.0 27900.0 0.35 0.5745 0.9903 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B13 mock treatment 433600.0 22700.0 0.25 476400.0 48700.0 0.61 0.6067 0.9219 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B14 mock treatment 458000.0 47100.0 0.52 462400.0 34700.0 0.43 0.6718 0.9963 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B15 compound treatment 460800.0 49900.0 0.55 478800.0 51100.0 0.64 0.8385 0.997 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B16 compound treatment 434000.0 23100.0 0.25 461200.0 33500.0 0.42 0.4753 0.9708 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B17 compound treatment 458400.0 47500.0 0.52 460400.0 32700.0 0.41 0.6572 0.9929 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B18 compound treatment 528800.0 118000.0 1.29 474000.0 46300.0 0.58 1.3225 0.9346 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B19 compound treatment 427200.0 16300.0 0.18 435200.0 7520.0 0.09 0.1928 0.9551 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B20 compound treatment 486400.0 75500.0 0.83 531200.0 104000.0 1.29 1.5001 0.9765 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B21 compound treatment 427600.0 16700.0 0.18 446800.0 19100.0 0.24 0.2984 0.9913 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B22 compound treatment 519600.0 109000.0 1.19 502800.0 75100.0 0.94 1.506 0.9931 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B23 compound treatment 471200.0 60300.0 0.66 448400.0 20700.0 0.26 0.6502 0.9165 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 B24 compound treatment 553200.0 142000.0 1.56 533600.0 106000.0 1.32 2.0385 0.9967 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C01 compound treatment 555200.0 144000.0 1.58 514400.0 86700.0 1.08 1.8842 0.9831 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C02 compound treatment 473200.0 62300.0 0.68 503200.0 75500.0 0.94 1.1503 0.9873 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C03 compound treatment 438800.0 27900.0 0.31 437200.0 9520.0 0.12 0.3003 0.9155 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C04 compound treatment 422400.0 11500.0 0.13 430400.0 2720.0 0.03 0.1131 0.8668 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C05 compound treatment 424000.0 13100.0 0.14 423600.0 -4080.0 -0.05 0.0654 0.4292 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C06 compound treatment 410400.0 -489.0 -0.01 403600.0 -24100.0 -0.3 -0.2168 -0.7196 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C07 compound treatment 409200.0 -1690.0 -0.02 413600.0 -14100.0 -0.18 -0.1376 -0.7771 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C08 compound treatment 403200.0 -7690.0 -0.08 407200.0 -20500.0 -0.26 -0.2407 -0.8925 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C09 compound treatment 396000.0 -14900.0 -0.16 420400.0 -7280.0 -0.09 -0.1797 -0.9622 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C10 compound treatment 438000.0 27100.0 0.3 440400.0 12700.0 0.16 0.3224 0.9572 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C11 mock treatment 398800.0 -12100.0 -0.13 441200.0 13500.0 0.17 0.0259 0.1208 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C12 mock treatment 388000.0 -22900.0 -0.25 428800.0 1120.0 0.01 -0.1673 -0.6667 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C13 compound treatment 370800.0 -40100.0 -0.44 410400.0 -17300.0 -0.22 -0.4632 -0.9467 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C14 compound treatment 426400.0 15500.0 0.17 414000.0 -13700.0 -0.17 -9.0E-4 -0.0038 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C15 mock treatment 452000.0 41100.0 0.45 412400.0 -15300.0 -0.19 0.1831 0.3745 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C16 mock treatment 417200.0 6310.0 0.07 411200.0 -16500.0 -0.21 -0.0969 -0.4457 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C17 compound treatment 401200.0 -9690.0 -0.11 433200.0 5520.0 0.07 -0.0262 -0.2073 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C18 compound treatment 426400.0 15500.0 0.17 410400.0 -17300.0 -0.22 -0.0328 -0.1192 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C19 compound treatment 420800.0 9910.0 0.11 413200.0 -14500.0 -0.18 -0.0514 -0.2432 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C20 compound treatment 455600.0 44700.0 0.49 432800.0 5120.0 0.06 0.3914 0.7928 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C21 compound treatment 429600.0 18700.0 0.2 390000.0 -37700.0 -0.47 -0.1884 -0.3666 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C22 compound treatment 424800.0 13900.0 0.15 458800.0 31100.0 0.39 0.3829 0.9162 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C23 compound treatment 474800.0 63900.0 0.7 480800.0 53100.0 0.66 0.9645 0.9997 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 C24 compound treatment 537200.0 126000.0 1.38 519200.0 91500.0 1.14 1.7873 0.9956 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D01 compound treatment 487600.0 76700.0 0.84 485600.0 57900.0 0.72 1.1061 0.9973 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D02 compound treatment 443600.0 32700.0 0.36 461600.0 33900.0 0.42 0.5532 0.9965 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D03 compound treatment 392400.0 -18500.0 -0.2 396000.0 -31700.0 -0.4 -0.4233 -0.9514 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D04 compound treatment 495600.0 84700.0 0.93 496400.0 68700.0 0.86 1.2635 0.9993 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D05 compound treatment 395600.0 -15300.0 -0.17 399600.0 -28100.0 -0.35 -0.3667 -0.9425 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D06 compound treatment 422400.0 11500.0 0.13 453200.0 25500.0 0.32 0.3148 0.9174 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D07 compound treatment 421600.0 10700.0 0.12 414800.0 -12900.0 -0.16 -0.031 -0.1556 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D08 compound treatment 488800.0 77900.0 0.85 448800.0 21100.0 0.26 0.79 0.8846 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D09 compound treatment 416000.0 5110.0 0.06 370000.0 -57700.0 -0.72 -0.4705 -0.6503 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D10 compound treatment 461600.0 50700.0 0.56 476800.0 49100.0 0.61 0.827 0.9987 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D11 mock treatment 368400.0 -42500.0 -0.47 404400.0 -23300.0 -0.29 -0.5349 -0.9745 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D12 mock treatment 413600.0 2710.0 0.03 399200.0 -28500.0 -0.36 -0.2309 -0.6459 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D13 compound treatment 389200.0 -21700.0 -0.24 400800.0 -26900.0 -0.34 -0.4057 -0.9855 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D14 compound treatment 414800.0 3910.0 0.04 424000.0 -3680.0 -0.05 -0.0023 -0.0365 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D15 mock treatment 387600.0 -23300.0 -0.25 400800.0 -26900.0 -0.34 -0.4181 -0.9907 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D16 mock treatment 380800.0 -30100.0 -0.33 430000.0 2320.0 0.03 -0.2125 -0.6425 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D17 compound treatment 375200.0 -35700.0 -0.39 359600.0 -68100.0 -0.85 -0.8784 -0.9376 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D18 compound treatment 418800.0 7910.0 0.09 456000.0 28300.0 0.35 0.3117 0.8549 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D19 compound treatment 395600.0 -15300.0 -0.17 400000.0 -27700.0 -0.35 -0.3632 -0.9444 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D20 compound treatment 399200.0 -11700.0 -0.13 394800.0 -32900.0 -0.41 -0.3813 -0.8853 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D21 compound treatment 418800.0 7910.0 0.09 412400.0 -15300.0 -0.19 -0.0739 -0.3522 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D22 compound treatment 424000.0 13100.0 0.14 428400.0 716.0 0.01 0.1078 0.7498 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D23 compound treatment 436400.0 25500.0 0.28 457600.0 29900.0 0.37 0.4621 0.9896 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 D24 compound treatment 495200.0 84300.0 0.92 510000.0 82300.0 1.03 1.3807 0.9985 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E01 mock treatment 514800.0 104000.0 1.14 506400.0 78700.0 0.98 1.5006 0.9974 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E02 mock treatment 451600.0 40700.0 0.45 466000.0 38300.0 0.48 0.654 0.9993 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E03 compound treatment 422000.0 11100.0 0.12 430800.0 3120.0 0.04 0.1136 0.8891 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E04 compound treatment 389200.0 -21700.0 -0.24 419200.0 -8480.0 -0.11 -0.2429 -0.934 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E05 compound treatment 387200.0 -23700.0 -0.26 387200.0 -40500.0 -0.51 -0.5414 -0.9517 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E06 compound treatment 390000.0 -20900.0 -0.23 408800.0 -18900.0 -0.24 -0.3287 -0.9999 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E07 compound treatment 394800.0 -16100.0 -0.18 386800.0 -40900.0 -0.51 -0.4861 -0.8989 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E08 compound treatment 360800.0 -50100.0 -0.55 402000.0 -25700.0 -0.32 -0.6149 -0.9675 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E09 mock treatment 374000.0 -36900.0 -0.4 404400.0 -23300.0 -0.29 -0.4915 -0.9871 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E10 mock treatment 370800.0 -40100.0 -0.44 378400.0 -49300.0 -0.62 -0.7462 -0.9862 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E11 compound treatment 363600.0 -47300.0 -0.52 367200.0 -60500.0 -0.76 -0.901 -0.9829 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E12 compound treatment 381600.0 -29300.0 -0.32 388400.0 -39300.0 -0.49 -0.5742 -0.9786 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E13 compound treatment 357600.0 -53300.0 -0.58 367200.0 -60500.0 -0.76 -0.9475 -0.9918 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E14 compound treatment 368000.0 -42900.0 -0.47 381600.0 -46100.0 -0.58 -0.7396 -0.9948 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E15 compound treatment 375200.0 -35700.0 -0.39 384000.0 -43700.0 -0.55 -0.6626 -0.9865 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E16 compound treatment 380000.0 -30900.0 -0.34 412000.0 -15700.0 -0.2 -0.3779 -0.9664 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E17 mock treatment 393600.0 -17300.0 -0.19 404800.0 -22900.0 -0.29 -0.3362 -0.9799 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E18 mock treatment 370400.0 -40500.0 -0.44 426400.0 -1280.0 -0.02 -0.3248 -0.7322 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E19 compound treatment 382400.0 -28500.0 -0.31 404800.0 -22900.0 -0.29 -0.4229 -0.9991 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E20 compound treatment 367600.0 -43300.0 -0.47 405600.0 -22100.0 -0.28 -0.5305 -0.967 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E21 compound treatment 388000.0 -22900.0 -0.25 412400.0 -15300.0 -0.19 -0.3124 -0.9911 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E22 compound treatment 420000.0 9110.0 0.1 410800.0 -16900.0 -0.21 -0.0788 -0.3373 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E23 compound treatment 433200.0 22300.0 0.24 445600.0 17900.0 0.22 0.3312 0.9991 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 E24 compound treatment 510400.0 99500.0 1.09 480000.0 52300.0 0.65 1.2331 0.9702 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F01 mock treatment 478000.0 67100.0 0.73 514800.0 87100.0 1.09 1.29 0.9816 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F02 mock treatment 409200.0 -1690.0 -0.02 446400.0 18700.0 0.23 0.1524 0.6492 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F03 compound treatment 403600.0 -7290.0 -0.08 399600.0 -28100.0 -0.35 -0.3048 -0.8462 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F04 compound treatment 426000.0 15100.0 0.17 414400.0 -13300.0 -0.17 -5.0E-4 -0.002 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F05 compound treatment 400800.0 -10100.0 -0.11 409600.0 -18100.0 -0.23 -0.238 -0.9457 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F06 compound treatment 401200.0 -9690.0 -0.11 422000.0 -5680.0 -0.07 -0.1253 -0.981 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F07 compound treatment 392800.0 -18100.0 -0.2 373200.0 -54500.0 -0.68 -0.6219 -0.8764 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F08 compound treatment 385600.0 -25300.0 -0.28 397200.0 -30500.0 -0.38 -0.4654 -0.9877 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F09 mock treatment 386000.0 -24900.0 -0.27 395200.0 -32500.0 -0.41 -0.48 -0.9811 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F10 mock treatment 382800.0 -28100.0 -0.31 406400.0 -21300.0 -0.27 -0.4057 -0.9974 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F11 compound treatment 356400.0 -54500.0 -0.6 357600.0 -70100.0 -0.88 -1.0416 -0.9824 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F12 compound treatment 374000.0 -36900.0 -0.4 398000.0 -29700.0 -0.37 -0.5481 -0.9991 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F13 compound treatment 384400.0 -26500.0 -0.29 428400.0 716.0 0.01 -0.1988 -0.6849 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F14 compound treatment 397200.0 -13700.0 -0.15 411200.0 -16500.0 -0.21 -0.2518 -0.9877 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F15 compound treatment 372400.0 -38500.0 -0.42 389600.0 -38100.0 -0.48 -0.6348 -0.9981 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F16 compound treatment 387200.0 -23700.0 -0.26 409600.0 -18100.0 -0.23 -0.3433 -0.9977 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F17 mock treatment 398800.0 -12100.0 -0.13 402000.0 -25700.0 -0.32 -0.3207 -0.9232 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F18 mock treatment 385200.0 -25700.0 -0.28 402800.0 -24900.0 -0.31 -0.4189 -0.9987 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F19 compound treatment 379200.0 -31700.0 -0.35 402800.0 -24900.0 -0.31 -0.4654 -0.9985 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F20 compound treatment 390000.0 -20900.0 -0.23 430400.0 2720.0 0.03 -0.1377 -0.5956 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F21 compound treatment 394400.0 -16500.0 -0.18 412800.0 -14900.0 -0.19 -0.2593 -0.9999 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F22 compound treatment 442400.0 31500.0 0.35 426400.0 -1280.0 -0.02 0.2326 0.6735 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F23 compound treatment 438400.0 27500.0 0.3 454000.0 26300.0 0.33 0.4457 0.999 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 F24 compound treatment 507600.0 96700.0 1.06 565200.0 138000.0 1.72 1.9649 0.9729 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G01 compound treatment 468800.0 57900.0 0.63 511200.0 83500.0 1.04 1.1869 0.9714 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G02 compound treatment 374400.0 -36500.0 -0.4 426000.0 -1680.0 -0.02 -0.2974 -0.7433 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G03 mock treatment 389200.0 -21700.0 -0.24 452400.0 24700.0 0.31 0.0506 0.1299 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G04 mock treatment 382000.0 -28900.0 -0.32 399600.0 -28100.0 -0.35 -0.472 -0.9986 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G05 compound treatment 380800.0 -30100.0 -0.33 394400.0 -33300.0 -0.42 -0.5273 -0.9933 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G06 compound treatment 343600.0 -67300.0 -0.74 378000.0 -49700.0 -0.62 -0.9603 -0.9964 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G07 compound treatment 333600.0 -77300.0 -0.85 353600.0 -74100.0 -0.93 -1.2535 -0.999 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G08 compound treatment 326800.0 -84100.0 -0.92 339200.0 -88500.0 -1.11 -1.4335 -0.9958 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G09 compound treatment 343600.0 -67300.0 -0.74 350400.0 -77300.0 -0.97 -1.2044 -0.991 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G10 compound treatment 344000.0 -66900.0 -0.73 390800.0 -36900.0 -0.46 -0.8441 -0.9752 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G11 compound treatment 335200.0 -75700.0 -0.83 376000.0 -51700.0 -0.65 -1.0431 -0.9924 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G12 compound treatment 359600.0 -51300.0 -0.56 348400.0 -79300.0 -0.99 -1.0982 -0.9638 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G13 compound treatment 356800.0 -54100.0 -0.59 372800.0 -54900.0 -0.69 -0.9041 -0.9973 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G14 compound treatment 341600.0 -69300.0 -0.76 355600.0 -72100.0 -0.9 -1.1739 -0.9963 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G15 compound treatment 368000.0 -42900.0 -0.47 364400.0 -63300.0 -0.79 -0.8917 -0.9689 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G16 compound treatment 336800.0 -74100.0 -0.81 349600.0 -78100.0 -0.98 -1.2641 -0.9958 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G17 compound treatment 348000.0 -62900.0 -0.69 383600.0 -44100.0 -0.55 -0.8768 -0.9939 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G18 compound treatment 327200.0 -83700.0 -0.92 357200.0 -70500.0 -0.88 -1.2713 -0.9998 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G19 mock treatment 374400.0 -36500.0 -0.4 382000.0 -45700.0 -0.57 -0.6865 -0.9847 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G20 mock treatment 371200.0 -39700.0 -0.43 388800.0 -38900.0 -0.49 -0.6512 -0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G21 compound treatment 391600.0 -19300.0 -0.21 398400.0 -29300.0 -0.37 -0.4083 -0.9658 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G22 compound treatment 396800.0 -14100.0 -0.15 404800.0 -22900.0 -0.29 -0.3115 -0.958 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G23 compound treatment 399600.0 -11300.0 -0.12 455200.0 27500.0 0.34 0.1559 0.4264 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 G24 compound treatment 488000.0 77100.0 0.84 512800.0 85100.0 1.06 1.3497 0.9934 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H01 compound treatment 433200.0 22300.0 0.24 446400.0 18700.0 0.23 0.3383 0.9998 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H02 compound treatment 413200.0 2310.0 0.03 400400.0 -27300.0 -0.34 -0.2234 -0.6529 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H03 mock treatment 425200.0 14300.0 0.16 422400.0 -5280.0 -0.07 0.0641 0.3768 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H04 mock treatment 418800.0 7910.0 0.09 374000.0 -53700.0 -0.67 -0.4135 -0.6108 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H05 compound treatment 398000.0 -12900.0 -0.14 415600.0 -12100.0 -0.15 -0.2067 -0.9994 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H06 compound treatment 398800.0 -12100.0 -0.13 416000.0 -11700.0 -0.15 -0.1969 -0.9988 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H07 compound treatment 374400.0 -36500.0 -0.4 417600.0 -10100.0 -0.13 -0.3717 -0.8872 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H08 compound treatment 343600.0 -67300.0 -0.74 391600.0 -36100.0 -0.45 -0.8401 -0.9723 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H09 compound treatment 338800.0 -72100.0 -0.79 381200.0 -46500.0 -0.58 -0.9692 -0.9887 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H10 compound treatment 352400.0 -58500.0 -0.64 402000.0 -25700.0 -0.32 -0.68 -0.9491 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H11 compound treatment 365600.0 -45300.0 -0.5 387200.0 -40500.0 -0.51 -0.7087 -0.9999 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H12 compound treatment 378800.0 -32100.0 -0.35 400400.0 -27300.0 -0.34 -0.4897 -0.9999 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H13 compound treatment 380800.0 -30100.0 -0.33 391600.0 -36100.0 -0.45 -0.5521 -0.988 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H14 compound treatment 360400.0 -50500.0 -0.55 408000.0 -19700.0 -0.25 -0.565 -0.9336 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H15 compound treatment 368400.0 -42500.0 -0.47 364400.0 -63300.0 -0.79 -0.8886 -0.9679 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H16 compound treatment 367200.0 -43700.0 -0.48 384800.0 -42900.0 -0.54 -0.7175 -0.9984 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H17 compound treatment 350800.0 -60100.0 -0.66 405200.0 -22500.0 -0.28 -0.6641 -0.9281 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H18 compound treatment 453200.0 42300.0 0.46 422400.0 -5280.0 -0.07 0.2809 0.6002 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H19 mock treatment 366800.0 -44100.0 -0.48 394400.0 -33300.0 -0.42 -0.6357 -0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H20 mock treatment 389600.0 -21300.0 -0.23 412400.0 -15300.0 -0.19 -0.3 -0.9951 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H21 compound treatment 389600.0 -21300.0 -0.23 392800.0 -34900.0 -0.44 -0.4733 -0.9569 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H22 compound treatment 407600.0 -3290.0 -0.04 436400.0 8720.0 0.11 0.0516 0.4496 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H23 compound treatment 439600.0 28700.0 0.31 439600.0 11900.0 0.15 0.3277 0.9418 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 H24 compound treatment 474000.0 63100.0 0.69 520400.0 92700.0 1.16 1.3086 0.9694 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I01 compound treatment 489600.0 78700.0 0.86 520000.0 92300.0 1.15 1.4258 0.9896 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I02 compound treatment 451200.0 40300.0 0.44 460400.0 32700.0 0.41 0.6014 0.9993 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I03 compound treatment 411200.0 311.0 0.0 447200.0 19500.0 0.24 0.175 0.7169 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I04 compound treatment 378800.0 -32100.0 -0.35 383200.0 -44500.0 -0.56 -0.6418 -0.9754 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I05 mock treatment 385200.0 -25700.0 -0.28 367600.0 -60100.0 -0.75 -0.7302 -0.9101 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I06 mock treatment 374000.0 -36900.0 -0.4 381600.0 -46100.0 -0.58 -0.6931 -0.9849 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I07 compound treatment 362400.0 -48500.0 -0.53 380400.0 -47300.0 -0.59 -0.7936 -0.9986 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I08 compound treatment 351600.0 -59300.0 -0.65 383200.0 -44500.0 -0.56 -0.8524 -0.997 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I09 compound treatment 326400.0 -84500.0 -0.93 358400.0 -69300.0 -0.87 -1.2668 -0.9995 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I10 compound treatment 340400.0 -70500.0 -0.77 374400.0 -53300.0 -0.67 -1.017 -0.9973 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I11 compound treatment 361200.0 -49700.0 -0.54 348000.0 -79700.0 -1.0 -1.0894 -0.9595 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I12 compound treatment 336000.0 -74900.0 -0.82 334000.0 -93700.0 -1.17 -1.4083 -0.9848 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I13 compound treatment 365600.0 -45300.0 -0.5 404400.0 -23300.0 -0.29 -0.5566 -0.9678 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I14 compound treatment 366000.0 -44900.0 -0.49 397200.0 -30500.0 -0.38 -0.6171 -0.9921 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I15 compound treatment 346400.0 -64500.0 -0.71 363600.0 -64100.0 -0.8 -1.066 -0.998 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I16 compound treatment 348400.0 -62500.0 -0.68 385600.0 -42100.0 -0.53 -0.856 -0.9916 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I17 compound treatment 366800.0 -44100.0 -0.48 400000.0 -27700.0 -0.35 -0.5862 -0.9867 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I18 compound treatment 370400.0 -40500.0 -0.44 357200.0 -70500.0 -0.88 -0.9368 -0.9494 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I19 compound treatment 380800.0 -30100.0 -0.33 378400.0 -49300.0 -0.62 -0.6688 -0.9569 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I20 compound treatment 384800.0 -26100.0 -0.29 401200.0 -26500.0 -0.33 -0.4362 -0.9973 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I21 mock treatment 377200.0 -33700.0 -0.37 418000.0 -9680.0 -0.12 -0.3465 -0.8924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I22 mock treatment 403600.0 -7290.0 -0.08 434800.0 7120.0 0.09 0.0065 0.0544 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I23 compound treatment 433200.0 22300.0 0.24 466000.0 38300.0 0.48 0.5116 0.9511 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 I24 compound treatment 459200.0 48300.0 0.53 479200.0 51500.0 0.64 0.8296 0.9952 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J01 compound treatment 451200.0 40300.0 0.44 526000.0 98300.0 1.23 1.1815 0.9044 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J02 compound treatment 453200.0 42300.0 0.46 472000.0 44300.0 0.55 0.7195 0.996 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J03 compound treatment 457200.0 46300.0 0.51 428800.0 1120.0 0.01 0.3684 0.7263 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J04 compound treatment 415200.0 4310.0 0.05 415200.0 -12500.0 -0.16 -0.077 -0.4722 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J05 mock treatment 384000.0 -26900.0 -0.29 408400.0 -19300.0 -0.24 -0.3787 -0.9951 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J06 mock treatment 426800.0 15900.0 0.17 410800.0 -16900.0 -0.21 -0.0261 -0.0954 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J07 compound treatment 390000.0 -20900.0 -0.23 367600.0 -60100.0 -0.75 -0.6931 -0.8824 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J08 compound treatment 398800.0 -12100.0 -0.13 382800.0 -44900.0 -0.56 -0.4905 -0.8505 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J09 compound treatment 398000.0 -12900.0 -0.14 366400.0 -61300.0 -0.77 -0.6417 -0.8235 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J10 compound treatment 383200.0 -27700.0 -0.3 350000.0 -77700.0 -0.97 -0.9014 -0.8856 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J11 compound treatment 385600.0 -25300.0 -0.28 383200.0 -44500.0 -0.56 -0.5892 -0.9481 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J12 compound treatment 384400.0 -26500.0 -0.29 400800.0 -26900.0 -0.34 -0.4428 -0.9973 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J13 compound treatment 393200.0 -17700.0 -0.19 412800.0 -14900.0 -0.19 -0.2686 -0.9998 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J14 compound treatment 397200.0 -13700.0 -0.15 404000.0 -23700.0 -0.3 -0.3154 -0.9502 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J15 compound treatment 389600.0 -21300.0 -0.23 410800.0 -16900.0 -0.21 -0.3141 -0.9988 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J16 compound treatment 398000.0 -12900.0 -0.14 419600.0 -8080.0 -0.1 -0.1713 -0.9866 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J17 compound treatment 386800.0 -24100.0 -0.26 402400.0 -25300.0 -0.32 -0.4101 -0.9959 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J18 compound treatment 411200.0 311.0 0.0 442800.0 15100.0 0.19 0.1361 0.7197 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J19 compound treatment 407600.0 -3290.0 -0.04 376400.0 -51300.0 -0.64 -0.479 -0.7456 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J20 compound treatment 382400.0 -28500.0 -0.31 431200.0 3520.0 0.04 -0.1895 -0.6015 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J21 mock treatment 408000.0 -2890.0 -0.03 424400.0 -3280.0 -0.04 -0.0514 -0.9917 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J22 mock treatment 428400.0 17500.0 0.19 456000.0 28300.0 0.35 0.386 0.9585 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J23 compound treatment 480000.0 69100.0 0.76 482000.0 54300.0 0.68 1.0154 0.9985 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 J24 compound treatment 520400.0 110000.0 1.2 564800.0 137000.0 1.71 2.0604 0.9847 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K01 compound treatment 476000.0 65100.0 0.71 476000.0 48300.0 0.6 0.9314 0.9966 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K02 compound treatment 415200.0 4310.0 0.05 446000.0 18300.0 0.23 0.1954 0.8353 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K03 compound treatment 433200.0 22300.0 0.24 450800.0 23100.0 0.29 0.3772 0.9965 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K04 compound treatment 364000.0 -46900.0 -0.51 395200.0 -32500.0 -0.41 -0.6503 -0.9933 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K05 compound treatment 365200.0 -45700.0 -0.5 380800.0 -46900.0 -0.59 -0.7684 -0.9969 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K06 compound treatment 378000.0 -32900.0 -0.36 387600.0 -40100.0 -0.5 -0.6091 -0.9868 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K07 mock treatment 364800.0 -46100.0 -0.5 400000.0 -27700.0 -0.35 -0.6017 -0.9831 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K08 mock treatment 367200.0 -43700.0 -0.48 384400.0 -43300.0 -0.54 -0.721 -0.9981 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K09 compound treatment 355600.0 -55300.0 -0.61 354000.0 -73700.0 -0.92 -1.0797 -0.9792 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K10 compound treatment 337600.0 -73300.0 -0.8 368000.0 -59700.0 -0.75 -1.0952 -0.9993 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K11 compound treatment 344400.0 -66500.0 -0.73 380000.0 -47700.0 -0.6 -0.9365 -0.9951 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K12 compound treatment 340400.0 -70500.0 -0.77 375200.0 -52500.0 -0.66 -1.0099 -0.9968 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K13 compound treatment 359600.0 -51300.0 -0.56 365600.0 -62100.0 -0.78 -0.9461 -0.9874 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K14 compound treatment 370000.0 -40900.0 -0.45 378000.0 -49700.0 -0.62 -0.7559 -0.9871 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K15 mock treatment 366800.0 -44100.0 -0.48 384800.0 -42900.0 -0.54 -0.7206 -0.9986 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K16 mock treatment 356400.0 -54500.0 -0.6 391600.0 -36100.0 -0.45 -0.741 -0.9905 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K17 compound treatment 318000.0 -92900.0 -1.02 389600.0 -38100.0 -0.48 -1.056 -0.9402 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K18 compound treatment 345600.0 -65300.0 -0.71 383200.0 -44500.0 -0.56 -0.8989 -0.9923 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K19 compound treatment 371600.0 -39300.0 -0.43 386400.0 -41300.0 -0.52 -0.6693 -0.9959 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K20 compound treatment 361200.0 -49700.0 -0.54 403600.0 -24100.0 -0.3 -0.5977 -0.9611 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K21 compound treatment 380000.0 -30900.0 -0.34 397600.0 -30100.0 -0.38 -0.5052 -0.9986 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K22 compound treatment 419200.0 8310.0 0.09 438000.0 10300.0 0.13 0.1556 0.9854 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K23 mock treatment 438000.0 27100.0 0.3 450400.0 22700.0 0.28 0.4108 0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 K24 mock treatment 490400.0 79500.0 0.87 509600.0 81900.0 1.02 1.34 0.9967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L01 compound treatment 453600.0 42700.0 0.47 472800.0 45100.0 0.56 0.7297 0.9956 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L02 compound treatment 433200.0 22300.0 0.24 408400.0 -19300.0 -0.24 0.0022 0.0064 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L03 compound treatment 408800.0 -2090.0 -0.02 431600.0 3920.0 0.05 0.0185 0.3415 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L04 compound treatment 407600.0 -3290.0 -0.04 412000.0 -15700.0 -0.2 -0.1642 -0.8232 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L05 compound treatment 445200.0 34300.0 0.38 438400.0 10700.0 0.13 0.3604 0.9036 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L06 compound treatment 423600.0 12700.0 0.14 398800.0 -28900.0 -0.36 -0.157 -0.4056 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L07 mock treatment 406800.0 -4090.0 -0.04 412400.0 -15300.0 -0.19 -0.1668 -0.8497 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L08 mock treatment 402400.0 -8490.0 -0.09 418000.0 -9680.0 -0.12 -0.1514 -0.9915 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L09 compound treatment 410800.0 -88.9 0.0 408000.0 -19700.0 -0.25 -0.1748 -0.7099 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L10 compound treatment 411600.0 711.0 0.01 391600.0 -36100.0 -0.45 -0.3136 -0.6948 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L11 compound treatment 401200.0 -9690.0 -0.11 457200.0 29500.0 0.37 0.186 0.4843 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L12 compound treatment 414400.0 3510.0 0.04 411600.0 -16100.0 -0.2 -0.1151 -0.5618 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L13 compound treatment 437200.0 26300.0 0.29 402800.0 -24900.0 -0.31 -0.0163 -0.0385 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L14 compound treatment 386800.0 -24100.0 -0.26 426400.0 -1280.0 -0.02 -0.1979 -0.7488 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L15 mock treatment 396800.0 -14100.0 -0.15 420000.0 -7680.0 -0.1 -0.177 -0.9741 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L16 mock treatment 401200.0 -9690.0 -0.11 416800.0 -10900.0 -0.14 -0.1713 -0.9924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L17 compound treatment 383200.0 -27700.0 -0.3 422000.0 -5680.0 -0.07 -0.2646 -0.8499 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L18 compound treatment 386000.0 -24900.0 -0.27 398000.0 -29700.0 -0.37 -0.4552 -0.9884 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L19 compound treatment 408000.0 -2890.0 -0.03 419600.0 -8080.0 -0.1 -0.0939 -0.886 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L20 compound treatment 423600.0 12700.0 0.14 432800.0 5120.0 0.06 0.1437 0.9378 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L21 compound treatment 392800.0 -18100.0 -0.2 442400.0 14700.0 0.18 -0.0099 -0.0367 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L22 compound treatment 422000.0 11100.0 0.12 429600.0 1920.0 0.02 0.103 0.8304 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L23 mock treatment 478400.0 67500.0 0.74 490400.0 62700.0 0.78 1.0773 0.9996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 L24 mock treatment 508400.0 97500.0 1.07 534000.0 106000.0 1.33 1.6952 0.9941 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M01 compound treatment 528000.0 117000.0 1.28 498400.0 70700.0 0.88 1.5321 0.9836 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M02 compound treatment 492400.0 81500.0 0.89 454800.0 27100.0 0.34 0.8709 0.9122 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M03 compound treatment 462000.0 51100.0 0.56 423600.0 -4080.0 -0.05 0.3596 0.6399 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M04 compound treatment 419600.0 8710.0 0.1 403600.0 -24100.0 -0.3 -0.1455 -0.4606 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M05 compound treatment 357200.0 -53700.0 -0.59 408000.0 -19700.0 -0.25 -0.5898 -0.9254 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M06 compound treatment 361600.0 -49300.0 -0.54 401200.0 -26500.0 -0.33 -0.6158 -0.9725 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M07 compound treatment 377600.0 -33300.0 -0.36 326800.0 -101000.0 -1.26 -1.1499 -0.8756 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M08 compound treatment 363600.0 -47300.0 -0.52 387200.0 -40500.0 -0.51 -0.7241 -0.9999 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M09 mock treatment 402400.0 -8490.0 -0.09 410400.0 -17300.0 -0.22 -0.2186 -0.9289 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M10 mock treatment 377600.0 -33300.0 -0.36 411200.0 -16500.0 -0.21 -0.4035 -0.9636 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M11 compound treatment 381200.0 -29700.0 -0.33 402800.0 -24900.0 -0.31 -0.4499 -0.9998 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M12 compound treatment 362800.0 -48100.0 -0.53 378400.0 -49300.0 -0.62 -0.8082 -0.9969 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M13 mock treatment 382800.0 -28100.0 -0.31 408400.0 -19300.0 -0.24 -0.388 -0.9928 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M14 mock treatment 394400.0 -16500.0 -0.18 432000.0 4320.0 0.05 -0.0895 -0.4749 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M15 compound treatment 370800.0 -40100.0 -0.44 358800.0 -68900.0 -0.86 -0.9195 -0.9511 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M16 compound treatment 366400.0 -44500.0 -0.49 400800.0 -26900.0 -0.34 -0.5822 -0.9836 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M17 compound treatment 394000.0 -16900.0 -0.18 404000.0 -23700.0 -0.3 -0.3402 -0.9743 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M18 compound treatment 392000.0 -18900.0 -0.21 396400.0 -31300.0 -0.39 -0.4229 -0.9556 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M19 compound treatment 392800.0 -18100.0 -0.2 388400.0 -39300.0 -0.49 -0.4875 -0.9202 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M20 compound treatment 401600.0 -9290.0 -0.1 403600.0 -24100.0 -0.3 -0.2849 -0.8962 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M21 compound treatment 420000.0 9110.0 0.1 438400.0 10700.0 0.13 0.1653 0.9894 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M22 compound treatment 444000.0 33100.0 0.36 450400.0 22700.0 0.28 0.4572 0.9927 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M23 compound treatment 458400.0 47500.0 0.52 444000.0 16300.0 0.2 0.5121 0.9165 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 M24 compound treatment 512800.0 102000.0 1.12 481200.0 53500.0 0.67 1.2623 0.9701 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N01 compound treatment 530400.0 120000.0 1.31 540800.0 113000.0 1.41 1.9256 0.9992 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N02 compound treatment 494000.0 83100.0 0.91 483200.0 55500.0 0.69 1.1344 0.9911 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N03 compound treatment 470400.0 59500.0 0.65 472400.0 44700.0 0.56 0.8562 0.9971 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N04 compound treatment 476000.0 65100.0 0.71 422000.0 -5680.0 -0.07 0.4539 0.6335 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N05 compound treatment 441600.0 30700.0 0.34 431600.0 3920.0 0.05 0.2724 0.8016 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N06 compound treatment 445600.0 34700.0 0.38 457600.0 29900.0 0.37 0.5333 1.0 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N07 compound treatment 432400.0 21500.0 0.24 431200.0 3520.0 0.04 0.1976 0.8249 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N08 compound treatment 443600.0 32700.0 0.36 459600.0 31900.0 0.4 0.5355 0.9985 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N09 mock treatment 407200.0 -3690.0 -0.04 412000.0 -15700.0 -0.2 -0.1673 -0.8352 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N10 mock treatment 443200.0 32300.0 0.35 439600.0 11900.0 0.15 0.3555 0.9262 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N11 compound treatment 432000.0 21100.0 0.23 436800.0 9120.0 0.11 0.2441 0.9469 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N12 compound treatment 538400.0 128000.0 1.4 527200.0 99500.0 1.24 1.8673 0.9984 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N13 mock treatment 435200.0 24300.0 0.27 459200.0 31500.0 0.39 0.4669 0.9817 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N14 mock treatment 453600.0 42700.0 0.47 463200.0 35500.0 0.44 0.6448 0.9997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N15 compound treatment 432400.0 21500.0 0.24 417600.0 -10100.0 -0.13 0.0774 0.2896 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N16 compound treatment 398400.0 -12500.0 -0.14 410400.0 -17300.0 -0.22 -0.2495 -0.9756 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N17 compound treatment 410800.0 -88.9 0.0 408400.0 -19300.0 -0.24 -0.1712 -0.71 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N18 compound treatment 409200.0 -1690.0 -0.02 402000.0 -25700.0 -0.32 -0.2402 -0.7466 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N19 compound treatment 409600.0 -1290.0 -0.01 422800.0 -4880.0 -0.06 -0.0532 -0.8481 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N20 compound treatment 429200.0 18300.0 0.2 452000.0 24300.0 0.3 0.3568 0.9796 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N21 compound treatment 464400.0 53500.0 0.59 437200.0 9520.0 0.12 0.4985 0.8337 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N22 compound treatment 450800.0 39900.0 0.44 460400.0 32700.0 0.41 0.5983 0.9995 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N23 compound treatment 463600.0 52700.0 0.58 431600.0 3920.0 0.05 0.4427 0.7644 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 N24 compound treatment 584400.0 174000.0 1.9 607600.0 180000.0 2.25 2.9345 0.9965 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O01 compound treatment 589600.0 179000.0 1.96 552800.0 125000.0 1.56 2.4901 0.9939 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O02 compound treatment 518800.0 108000.0 1.18 547600.0 120000.0 1.5 1.8959 0.993 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O03 compound treatment 466400.0 55500.0 0.61 477200.0 49500.0 0.62 0.8677 1.0 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O04 compound treatment 461600.0 50700.0 0.56 463200.0 35500.0 0.44 0.7067 0.9939 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O05 compound treatment 458400.0 47500.0 0.52 469200.0 41500.0 0.52 0.735 1.0 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O06 compound treatment 470000.0 59100.0 0.65 446400.0 18700.0 0.23 0.6232 0.9054 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O07 compound treatment 458000.0 47100.0 0.52 446400.0 18700.0 0.23 0.5303 0.9361 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O08 compound treatment 450800.0 39900.0 0.44 434800.0 7120.0 0.09 0.3719 0.834 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O09 compound treatment 435200.0 24300.0 0.27 421200.0 -6480.0 -0.08 0.1309 0.4704 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O10 compound treatment 434400.0 23500.0 0.26 442000.0 14300.0 0.18 0.3086 0.9843 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O11 mock treatment 422800.0 11900.0 0.13 480800.0 53100.0 0.66 0.5619 0.8301 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O12 mock treatment 427600.0 16700.0 0.18 446800.0 19100.0 0.24 0.2984 0.9913 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O13 compound treatment 430000.0 19100.0 0.21 430800.0 3120.0 0.04 0.1755 0.8246 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O14 compound treatment 433600.0 22700.0 0.25 496800.0 69100.0 0.86 0.7871 0.875 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O15 compound treatment 418800.0 7910.0 0.09 438800.0 11100.0 0.14 0.1596 0.9741 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O16 compound treatment 479200.0 68300.0 0.75 453600.0 25900.0 0.32 0.7581 0.93 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O17 compound treatment 474400.0 63500.0 0.7 451200.0 23500.0 0.29 0.6997 0.9267 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O18 compound treatment 443600.0 32700.0 0.36 464400.0 36700.0 0.46 0.578 0.9924 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O19 compound treatment 461600.0 50700.0 0.56 474000.0 46300.0 0.58 0.8022 0.9998 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O20 compound treatment 460400.0 49500.0 0.54 427200.0 -484.0 -0.01 0.3791 0.6992 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O21 compound treatment 462400.0 51500.0 0.56 478400.0 50700.0 0.63 0.8473 0.9983 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O22 compound treatment 480000.0 69100.0 0.76 517200.0 89500.0 1.12 1.3267 0.9818 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O23 compound treatment 534400.0 124000.0 1.35 489600.0 61900.0 0.77 1.5038 0.965 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 O24 compound treatment 588000.0 177000.0 1.94 592400.0 165000.0 2.06 2.8279 0.9995 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P01 compound treatment 642800.0 232000.0 2.54 600800.0 173000.0 2.17 3.3265 0.9969 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P02 compound treatment 566000.0 155000.0 1.7 614400.0 187000.0 2.34 2.8521 0.9878 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P03 compound treatment 510000.0 99100.0 1.09 523200.0 95500.0 1.19 1.612 0.9989 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P04 compound treatment 563600.0 153000.0 1.67 577600.0 150000.0 1.87 2.5081 0.9984 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P05 compound treatment 573200.0 162000.0 1.78 518400.0 90700.0 1.13 2.0589 0.9765 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P06 compound treatment 654800.0 244000.0 2.67 600800.0 173000.0 2.17 3.4194 0.9946 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P07 compound treatment 489200.0 78300.0 0.86 507600.0 79900.0 1.0 1.313 0.9971 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P08 compound treatment 507600.0 96700.0 1.06 506400.0 78700.0 0.98 1.4449 0.9993 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P09 compound treatment 490400.0 79500.0 0.87 482400.0 54700.0 0.68 1.0995 0.9929 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P10 compound treatment 522400.0 112000.0 1.22 546000.0 118000.0 1.48 1.9097 0.9954 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P11 mock treatment 563200.0 152000.0 1.67 538000.0 110000.0 1.38 2.1548 0.9956 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P12 mock treatment 494000.0 83100.0 0.91 558800.0 131000.0 1.64 1.803 0.9614 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P13 compound treatment 497200.0 86300.0 0.95 511200.0 83500.0 1.04 1.4068 0.9988 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P14 compound treatment 601600.0 191000.0 2.09 583600.0 156000.0 1.95 2.8554 0.9994 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P15 compound treatment 502000.0 91100.0 1.0 514000.0 86300.0 1.08 1.4687 0.9992 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P16 compound treatment 570000.0 159000.0 1.74 575600.0 148000.0 1.85 2.54 0.9996 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P17 compound treatment 488400.0 77500.0 0.85 515600.0 87900.0 1.1 1.3776 0.9918 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P18 compound treatment 522400.0 112000.0 1.22 503600.0 75900.0 0.95 1.5347 0.9923 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P19 compound treatment 549600.0 139000.0 1.52 554400.0 127000.0 1.58 2.1945 0.9998 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P20 compound treatment 550800.0 140000.0 1.53 547200.0 120000.0 1.49 2.1402 0.9999 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P21 compound treatment 533200.0 122000.0 1.34 552400.0 125000.0 1.56 2.0499 0.9971 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P22 compound treatment 618400.0 208000.0 2.27 671600.0 244000.0 3.05 3.7637 0.9895 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P23 compound treatment 601200.0 190000.0 2.08 650400.0 223000.0 2.79 3.443 0.9898 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2101 P24 compound treatment 764400.0 354000.0 3.87 763200.0 336000.0 4.2 5.7041 0.9992 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A01 compound treatment 444800.0 11500.0 0.13 502800.0 27600.0 0.35 0.3332 0.9063 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A02 compound treatment 307600.0 -126000.0 -1.38 348800.0 -126000.0 -1.58 -2.0909 -0.9976 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A03 compound treatment 300400.0 -133000.0 -1.46 292800.0 -182000.0 -2.28 -2.6419 -0.9764 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A04 compound treatment 363200.0 -70100.0 -0.77 337600.0 -138000.0 -1.72 -1.7595 -0.9339 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A05 compound treatment 325200.0 -108000.0 -1.18 366400.0 -109000.0 -1.36 -1.799 -0.9976 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A06 compound treatment 313600.0 -120000.0 -1.31 294000.0 -181000.0 -2.27 -2.5291 -0.9662 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A07 compound treatment 354800.0 -78500.0 -0.86 379200.0 -96000.0 -1.2 -1.4566 -0.9866 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A08 compound treatment 337600.0 -95700.0 -1.05 375600.0 -99600.0 -1.25 -1.6216 -0.9963 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A09 compound treatment 236000.0 -197000.0 -2.16 277600.0 -198000.0 -2.47 -3.2749 -0.9978 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A10 compound treatment 344400.0 -88900.0 -0.97 368000.0 -107000.0 -1.34 -1.6362 -0.9877 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A11 compound treatment 296000.0 -137000.0 -1.5 317200.0 -158000.0 -1.98 -2.4602 -0.9909 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A12 compound treatment 368400.0 -64900.0 -0.71 418400.0 -56800.0 -0.71 -1.0047 -1.0 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A13 mock treatment 528000.0 94700.0 1.04 564800.0 89600.0 1.12 1.5257 0.9992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A14 mock treatment 526800.0 93500.0 1.02 570800.0 95600.0 1.2 1.5695 0.997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A15 compound treatment 235600.0 -198000.0 -2.16 246400.0 -229000.0 -2.86 -3.5539 -0.9905 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A16 compound treatment 257600.0 -176000.0 -1.92 302000.0 -173000.0 -2.17 -2.8919 -0.9983 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A17 compound treatment 158800.0 -275000.0 -3.01 168400.0 -307000.0 -3.84 -4.8383 -0.9927 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A18 compound treatment 299200.0 -134000.0 -1.47 326000.0 -149000.0 -1.87 -2.3576 -0.993 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A19 compound treatment 564800.0 131000.0 1.44 617200.0 142000.0 1.78 2.274 0.9946 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A20 compound treatment 207600.0 -226000.0 -2.47 300800.0 -174000.0 -2.18 -3.2896 -0.9981 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A21 compound treatment 348000.0 -85300.0 -0.93 328000.0 -147000.0 -1.84 -1.962 -0.9506 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A22 compound treatment 311200.0 -122000.0 -1.34 314400.0 -161000.0 -2.01 -2.3672 -0.9804 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A23 compound treatment 404800.0 -28500.0 -0.31 384000.0 -91200.0 -1.14 -1.027 -0.8687 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 A24 compound treatment 525200.0 91900.0 1.01 485600.0 10400.0 0.13 0.8036 0.7921 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B01 compound treatment 512000.0 78700.0 0.86 552400.0 77200.0 0.97 1.2922 0.9984 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B02 compound treatment 355600.0 -77700.0 -0.85 381600.0 -93600.0 -1.17 -1.4292 -0.9877 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B03 compound treatment 295600.0 -138000.0 -1.51 308400.0 -167000.0 -2.09 -2.5411 -0.9873 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B04 compound treatment 300400.0 -133000.0 -1.46 378000.0 -97200.0 -1.22 -1.8884 -0.996 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B05 compound treatment 276000.0 -157000.0 -1.72 314000.0 -161000.0 -2.02 -2.6433 -0.9969 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B06 compound treatment 270800.0 -163000.0 -1.78 317200.0 -158000.0 -1.98 -2.6553 -0.9986 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B07 compound treatment 338000.0 -95300.0 -1.04 385200.0 -90000.0 -1.13 -1.5336 -0.9993 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B08 compound treatment 340000.0 -93300.0 -1.02 368400.0 -107000.0 -1.34 -1.6667 -0.9913 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B09 compound treatment 307600.0 -126000.0 -1.38 314400.0 -161000.0 -2.01 -2.3951 -0.9829 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B10 compound treatment 306000.0 -127000.0 -1.39 338800.0 -136000.0 -1.71 -2.1917 -0.995 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B11 compound treatment 268800.0 -165000.0 -1.8 290400.0 -185000.0 -2.31 -2.9077 -0.9924 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B12 compound treatment 320400.0 -113000.0 -1.24 366000.0 -109000.0 -1.37 -1.8397 -0.9988 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B13 mock treatment 472400.0 39100.0 0.43 523600.0 48400.0 0.61 0.7309 0.9855 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B14 mock treatment 466000.0 32700.0 0.36 560000.0 84800.0 1.06 1.0032 0.896 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B15 compound treatment 290800.0 -143000.0 -1.56 295600.0 -180000.0 -2.25 -2.6914 -0.9842 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B16 compound treatment 250000.0 -183000.0 -2.01 290800.0 -184000.0 -2.31 -3.0498 -0.9976 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B17 compound treatment 307600.0 -126000.0 -1.38 334000.0 -141000.0 -1.77 -2.2218 -0.9924 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B18 compound treatment 313200.0 -120000.0 -1.32 349200.0 -126000.0 -1.58 -2.044 -0.996 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B19 compound treatment 246400.0 -187000.0 -2.05 294400.0 -181000.0 -2.26 -3.0458 -0.9988 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B20 compound treatment 154000.0 -279000.0 -3.06 173600.0 -302000.0 -3.77 -4.8295 -0.9946 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B21 compound treatment 365200.0 -68100.0 -0.75 363600.0 -112000.0 -1.4 -1.514 -0.9569 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B22 compound treatment 266000.0 -167000.0 -1.83 277200.0 -198000.0 -2.48 -3.0462 -0.989 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B23 compound treatment 254800.0 -179000.0 -1.95 294000.0 -181000.0 -2.27 -2.9843 -0.9973 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 B24 compound treatment 305600.0 -128000.0 -1.4 321600.0 -154000.0 -1.92 -2.3469 -0.9878 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C01 compound treatment 528400.0 95100.0 1.04 538400.0 63200.0 0.79 1.2953 0.9908 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C02 compound treatment 275200.0 -158000.0 -1.73 297200.0 -178000.0 -2.23 -2.7981 -0.9923 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C03 compound treatment 222800.0 -211000.0 -2.31 227600.0 -248000.0 -3.1 -3.8193 -0.9894 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C04 compound treatment 394800.0 -38500.0 -0.42 411200.0 -64000.0 -0.8 -0.8639 -0.9552 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C05 compound treatment 332000.0 -101000.0 -1.11 354800.0 -120000.0 -1.51 -1.8489 -0.9887 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C06 compound treatment 20000.0 -413000.0 -4.53 19600.0 -456000.0 -5.7 -7.2288 -0.9935 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C07 compound treatment 296400.0 -137000.0 -1.5 307200.0 -168000.0 -2.1 -2.5455 -0.9863 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C08 compound treatment 241600.0 -192000.0 -2.1 254400.0 -221000.0 -2.76 -3.4367 -0.9909 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C09 compound treatment 12000.0 -421000.0 -4.61 11200.0 -464000.0 -5.8 -7.3651 -0.9935 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C10 compound treatment 330400.0 -103000.0 -1.13 351600.0 -124000.0 -1.55 -1.8896 -0.988 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C11 mock treatment 428800.0 -4510.0 -0.05 479600.0 4430.0 0.06 0.0042 0.0565 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C12 mock treatment 414400.0 -18900.0 -0.21 494800.0 19600.0 0.25 0.0271 0.0845 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C13 compound treatment 293600.0 -140000.0 -1.53 292000.0 -183000.0 -2.29 -2.7016 -0.9807 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C14 compound treatment 550800.0 117000.0 1.29 607200.0 132000.0 1.65 2.0772 0.9924 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C15 mock treatment 420800.0 -12500.0 -0.14 444400.0 -30800.0 -0.38 -0.369 -0.9033 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C16 mock treatment 434800.0 1490.0 0.02 466400.0 -8770.0 -0.11 -0.0661 -0.5958 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C17 compound treatment 231600.0 -202000.0 -2.21 262400.0 -213000.0 -2.66 -3.4434 -0.9957 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C18 compound treatment 242800.0 -191000.0 -2.09 262800.0 -212000.0 -2.66 -3.3531 -0.9929 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C19 compound treatment 304400.0 -129000.0 -1.41 345200.0 -130000.0 -1.63 -2.1475 -0.9975 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C20 compound treatment 270800.0 -163000.0 -1.78 289200.0 -186000.0 -2.33 -2.9029 -0.9913 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C21 compound treatment 305200.0 -128000.0 -1.4 341200.0 -134000.0 -1.68 -2.1767 -0.9961 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C22 compound treatment 256800.0 -177000.0 -1.93 261600.0 -214000.0 -2.67 -3.2553 -0.9874 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C23 compound treatment 258000.0 -175000.0 -1.92 266800.0 -208000.0 -2.61 -3.2001 -0.9887 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 C24 compound treatment 330000.0 -103000.0 -1.13 323600.0 -152000.0 -1.9 -2.1403 -0.9696 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D01 compound treatment 327200.0 -106000.0 -1.16 352400.0 -123000.0 -1.54 -1.9073 -0.9905 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D02 compound treatment 287200.0 -146000.0 -1.6 342400.0 -133000.0 -1.66 -2.3054 -0.9998 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D03 compound treatment 249200.0 -184000.0 -2.02 260800.0 -214000.0 -2.68 -3.3213 -0.9901 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D04 compound treatment 298000.0 -135000.0 -1.48 315200.0 -160000.0 -2.0 -2.4624 -0.9891 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D05 compound treatment 309600.0 -124000.0 -1.35 338800.0 -136000.0 -1.71 -2.1638 -0.9935 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D06 compound treatment 402400.0 -30900.0 -0.34 452000.0 -23200.0 -0.29 -0.4443 -0.997 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D07 compound treatment 333200.0 -100000.0 -1.1 380800.0 -94400.0 -1.18 -1.6097 -0.9993 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D08 compound treatment 451600.0 18300.0 0.2 481200.0 6030.0 0.08 0.1949 0.9109 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D09 compound treatment 333200.0 -100000.0 -1.1 340000.0 -135000.0 -1.69 -1.9705 -0.978 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D10 compound treatment 542800.0 109000.0 1.2 580400.0 105000.0 1.32 1.7782 0.9989 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D11 mock treatment 407200.0 -26100.0 -0.29 489200.0 14000.0 0.18 -0.0781 -0.2329 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D12 mock treatment 428400.0 -4910.0 -0.05 500800.0 25600.0 0.32 0.1886 0.5803 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D13 compound treatment 300800.0 -133000.0 -1.45 390800.0 -84400.0 -1.06 -1.7721 -0.9878 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D14 compound treatment 470000.0 36700.0 0.4 499600.0 24400.0 0.31 0.5 0.9909 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D15 mock treatment 400000.0 -33300.0 -0.36 480800.0 5630.0 0.07 -0.2082 -0.5604 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D16 mock treatment 424000.0 -9310.0 -0.1 476000.0 827.0 0.01 -0.0648 -0.6322 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D17 compound treatment 260800.0 -173000.0 -1.89 285600.0 -190000.0 -2.37 -3.0121 -0.9937 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D18 compound treatment 501600.0 68300.0 0.75 550000.0 74800.0 0.94 1.1904 0.9938 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D19 compound treatment 258000.0 -175000.0 -1.92 280000.0 -195000.0 -2.44 -3.0833 -0.9929 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D20 compound treatment 198800.0 -235000.0 -2.57 213200.0 -262000.0 -3.28 -4.1324 -0.9927 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D21 compound treatment 280800.0 -153000.0 -1.67 306000.0 -169000.0 -2.12 -2.6769 -0.9931 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D22 compound treatment 502400.0 69100.0 0.76 471200.0 -3970.0 -0.05 0.4998 0.6592 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D23 compound treatment 261600.0 -172000.0 -1.88 281200.0 -194000.0 -2.43 -3.0449 -0.9921 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 D24 compound treatment 492400.0 59100.0 0.65 558800.0 83600.0 1.05 1.197 0.9733 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E01 mock treatment 532800.0 99500.0 1.09 611200.0 136000.0 1.7 1.9732 0.9768 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E02 mock treatment 486400.0 53100.0 0.58 512400.0 37200.0 0.47 0.7402 0.9939 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E03 compound treatment 291600.0 -142000.0 -1.55 341600.0 -134000.0 -1.67 -2.2784 -0.9993 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E04 compound treatment 353200.0 -80100.0 -0.88 321200.0 -154000.0 -1.93 -1.9819 -0.9366 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E05 compound treatment 225600.0 -208000.0 -2.27 241600.0 -234000.0 -2.92 -3.6738 -0.9923 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E06 compound treatment 267600.0 -166000.0 -1.81 296000.0 -179000.0 -2.24 -2.8675 -0.9945 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E07 compound treatment 36400.0 -397000.0 -4.35 43600.0 -432000.0 -5.4 -6.8896 -0.9942 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E08 compound treatment 14000.0 -419000.0 -4.59 22400.0 -453000.0 -5.66 -7.2505 -0.9946 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E09 mock treatment 391600.0 -41700.0 -0.46 450000.0 -25200.0 -0.31 -0.5456 -0.9835 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E10 mock treatment 372000.0 -61300.0 -0.67 438400.0 -36800.0 -0.46 -0.7999 -0.983 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E11 compound treatment 215200.0 -218000.0 -2.39 260800.0 -214000.0 -2.68 -3.5845 -0.9983 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E12 compound treatment 329200.0 -104000.0 -1.14 353200.0 -122000.0 -1.53 -1.8847 -0.9897 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E13 compound treatment 206400.0 -227000.0 -2.48 193200.0 -282000.0 -3.53 -4.2504 -0.9853 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E14 compound treatment 198400.0 -235000.0 -2.57 236000.0 -239000.0 -2.99 -3.9339 -0.9972 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E15 compound treatment 244000.0 -189000.0 -2.07 342400.0 -133000.0 -1.66 -2.6399 -0.994 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E16 compound treatment 258800.0 -175000.0 -1.91 298800.0 -176000.0 -2.21 -2.9109 -0.9974 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E17 mock treatment 403200.0 -30100.0 -0.33 452800.0 -22400.0 -0.28 -0.431 -0.9967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E18 mock treatment 406800.0 -26500.0 -0.29 450000.0 -25200.0 -0.31 -0.4279 -0.9992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E19 compound treatment 211600.0 -222000.0 -2.43 285600.0 -190000.0 -2.37 -3.3931 -0.9999 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E20 compound treatment 352000.0 -81300.0 -0.89 394400.0 -80800.0 -1.01 -1.3439 -0.998 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E21 compound treatment 290400.0 -143000.0 -1.56 310400.0 -165000.0 -2.06 -2.5636 -0.9908 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E22 compound treatment 260000.0 -173000.0 -1.9 281600.0 -194000.0 -2.42 -3.0537 -0.9927 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E23 compound treatment 385600.0 -47700.0 -0.52 384800.0 -90400.0 -1.13 -1.1686 -0.9385 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 E24 compound treatment 144800.0 -289000.0 -3.16 208800.0 -266000.0 -3.33 -4.5894 -0.9996 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F01 mock treatment 457600.0 24300.0 0.27 606800.0 132000.0 1.65 1.352 0.8108 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F02 mock treatment 448400.0 15100.0 0.17 524800.0 49600.0 0.62 0.5557 0.8652 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F03 compound treatment 279600.0 -154000.0 -1.68 313600.0 -162000.0 -2.02 -2.619 -0.9959 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F04 compound treatment 451600.0 18300.0 0.2 451600.0 -23600.0 -0.29 -0.0669 -0.1877 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F05 compound treatment 306000.0 -127000.0 -1.39 280000.0 -195000.0 -2.44 -2.7117 -0.9647 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F06 compound treatment 408000.0 -25300.0 -0.28 407600.0 -67600.0 -0.85 -0.7936 -0.8923 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F07 compound treatment 354000.0 -79300.0 -0.87 362400.0 -113000.0 -1.41 -1.6114 -0.9729 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F08 compound treatment 410800.0 -22500.0 -0.25 499600.0 24400.0 0.31 0.0417 0.1062 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F09 mock treatment 399200.0 -34100.0 -0.37 440400.0 -34800.0 -0.43 -0.5716 -0.9971 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F10 mock treatment 395600.0 -37700.0 -0.41 460000.0 -15200.0 -0.19 -0.4262 -0.9378 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F11 compound treatment 286000.0 -147000.0 -1.61 345200.0 -130000.0 -1.63 -2.29 -1.0 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F12 compound treatment 400400.0 -32900.0 -0.36 532400.0 57200.0 0.72 0.2512 0.3135 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F13 compound treatment 11200.0 -422000.0 -4.62 16400.0 -459000.0 -5.74 -7.3253 -0.9943 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F14 compound treatment 395200.0 -38100.0 -0.42 441600.0 -33600.0 -0.42 -0.592 -1.0 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F15 compound treatment 223200.0 -210000.0 -2.3 286400.0 -189000.0 -2.36 -3.2962 -0.9999 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F16 compound treatment 517600.0 84300.0 0.92 568000.0 92800.0 1.16 1.4735 0.9935 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F17 mock treatment 419600.0 -13700.0 -0.15 459600.0 -15600.0 -0.19 -0.2439 -0.9917 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F18 mock treatment 403600.0 -29700.0 -0.33 465600.0 -9570.0 -0.12 -0.3147 -0.9078 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F19 compound treatment 243600.0 -190000.0 -2.08 269200.0 -206000.0 -2.58 -3.2903 -0.9943 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F20 compound treatment 413600.0 -19700.0 -0.22 475200.0 26.7 0.0 -0.1524 -0.706 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F21 compound treatment 359600.0 -73700.0 -0.81 379200.0 -96000.0 -1.2 -1.4194 -0.9814 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F22 compound treatment 391600.0 -41700.0 -0.46 432000.0 -43200.0 -0.54 -0.7048 -0.9965 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F23 compound treatment 268400.0 -165000.0 -1.81 292400.0 -183000.0 -2.29 -2.8932 -0.9932 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 F24 compound treatment 502800.0 69500.0 0.76 572000.0 96800.0 1.21 1.3943 0.9749 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G01 compound treatment 293200.0 -140000.0 -1.53 333600.0 -142000.0 -1.77 -2.3368 -0.9975 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G02 compound treatment 308000.0 -125000.0 -1.37 346000.0 -129000.0 -1.62 -2.1126 -0.9967 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G03 mock treatment 418800.0 -14500.0 -0.16 454000.0 -21200.0 -0.26 -0.2996 -0.9702 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G04 mock treatment 431200.0 -2110.0 -0.02 451600.0 -23600.0 -0.29 -0.2248 -0.7603 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G05 compound treatment 134800.0 -299000.0 -3.27 150400.0 -325000.0 -4.06 -5.1833 -0.9942 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G06 compound treatment 107600.0 -326000.0 -3.57 130000.0 -345000.0 -4.32 -5.5743 -0.9955 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G07 compound treatment 252400.0 -181000.0 -1.98 275600.0 -200000.0 -2.5 -3.1656 -0.9934 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G08 compound treatment 264000.0 -169000.0 -1.85 295600.0 -180000.0 -2.25 -2.8989 -0.9955 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G09 compound treatment 532800.0 99500.0 1.09 547600.0 72400.0 0.91 1.4108 0.9958 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G10 compound treatment 265200.0 -168000.0 -1.84 262400.0 -213000.0 -2.66 -3.1832 -0.9838 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G11 compound treatment 9200.0 -424000.0 -4.64 10400.0 -465000.0 -5.81 -7.3938 -0.9938 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G12 compound treatment 278000.0 -155000.0 -1.7 301200.0 -174000.0 -2.18 -2.741 -0.9926 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G13 compound treatment 190000.0 -243000.0 -2.66 234000.0 -241000.0 -3.02 -4.0166 -0.9981 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G14 compound treatment 255600.0 -178000.0 -1.95 280400.0 -195000.0 -2.44 -3.0984 -0.9938 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G15 compound treatment 6400.0 -427000.0 -4.67 10000.0 -465000.0 -5.82 -7.419 -0.9941 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G16 compound treatment 226400.0 -207000.0 -2.27 240000.0 -235000.0 -2.94 -3.6817 -0.9917 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G17 compound treatment 131200.0 -302000.0 -3.31 147200.0 -328000.0 -4.1 -5.2395 -0.9943 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G18 compound treatment 193600.0 -240000.0 -2.62 218000.0 -257000.0 -3.22 -4.1302 -0.9949 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G19 mock treatment 387600.0 -45700.0 -0.5 414400.0 -60800.0 -0.76 -0.8914 -0.9795 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G20 mock treatment 396400.0 -36900.0 -0.4 448000.0 -27200.0 -0.34 -0.5261 -0.9963 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G21 compound treatment 542800.0 109000.0 1.2 580000.0 105000.0 1.31 1.7747 0.999 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G22 compound treatment 275200.0 -158000.0 -1.73 288000.0 -187000.0 -2.34 -2.8794 -0.989 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G23 compound treatment 275600.0 -158000.0 -1.73 303600.0 -172000.0 -2.15 -2.7384 -0.9942 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 G24 compound treatment 150000.0 -283000.0 -3.1 166400.0 -309000.0 -3.86 -4.9241 -0.9941 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H01 compound treatment 293600.0 -140000.0 -1.53 306800.0 -168000.0 -2.11 -2.5707 -0.9877 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H02 compound treatment 493200.0 59900.0 0.66 509200.0 34000.0 0.43 0.7646 0.9781 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H03 mock treatment 449600.0 16300.0 0.18 438400.0 -36800.0 -0.46 -0.1991 -0.4037 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H04 mock treatment 426800.0 -6510.0 -0.07 466000.0 -9170.0 -0.11 -0.1316 -0.9739 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H05 compound treatment 238400.0 -195000.0 -2.13 272400.0 -203000.0 -2.54 -3.3023 -0.9963 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H06 compound treatment 400800.0 -32500.0 -0.36 448400.0 -26800.0 -0.33 -0.4885 -0.9995 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H07 compound treatment 246400.0 -187000.0 -2.05 284000.0 -191000.0 -2.39 -3.1378 -0.997 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H08 compound treatment 469200.0 35900.0 0.39 497600.0 22400.0 0.28 0.4762 0.9863 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H09 compound treatment 230800.0 -203000.0 -2.22 254000.0 -221000.0 -2.77 -3.5239 -0.994 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H10 compound treatment 318000.0 -115000.0 -1.26 311600.0 -164000.0 -2.05 -2.3393 -0.9731 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H11 compound treatment 256000.0 -177000.0 -1.94 314800.0 -160000.0 -2.01 -2.7911 -0.9999 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H12 compound treatment 406400.0 -26900.0 -0.29 440400.0 -34800.0 -0.43 -0.5159 -0.982 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H13 compound treatment 265200.0 -168000.0 -1.84 283600.0 -192000.0 -2.4 -2.9958 -0.9915 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H14 compound treatment 28000.0 -405000.0 -4.44 46400.0 -429000.0 -5.36 -6.9299 -0.9956 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H15 compound treatment 164400.0 -269000.0 -2.94 227600.0 -248000.0 -3.1 -4.2714 -0.9997 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H16 compound treatment 479600.0 46300.0 0.51 566800.0 91600.0 1.15 1.1686 0.9327 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H17 compound treatment 254000.0 -179000.0 -1.96 261600.0 -214000.0 -2.67 -3.277 -0.9885 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H18 compound treatment 47600.0 -386000.0 -4.22 59600.0 -416000.0 -5.2 -6.6614 -0.9947 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H19 mock treatment 424800.0 -8510.0 -0.09 456400.0 -18800.0 -0.23 -0.2319 -0.9181 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H20 mock treatment 422000.0 -11300.0 -0.12 440000.0 -35200.0 -0.44 -0.3986 -0.8723 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H21 compound treatment 256400.0 -177000.0 -1.94 302000.0 -173000.0 -2.17 -2.9012 -0.9985 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H22 compound treatment 358400.0 -74900.0 -0.82 392400.0 -82800.0 -1.04 -1.312 -0.9934 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H23 compound treatment 272800.0 -161000.0 -1.76 292000.0 -183000.0 -2.29 -2.8626 -0.9914 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 H24 compound treatment 515200.0 81900.0 0.9 572800.0 97600.0 1.22 1.4973 0.9885 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I01 compound treatment 337600.0 -95700.0 -1.05 378400.0 -96800.0 -1.21 -1.5969 -0.9974 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I02 compound treatment 255200.0 -178000.0 -1.95 302800.0 -172000.0 -2.16 -2.9034 -0.9987 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I03 compound treatment 267200.0 -166000.0 -1.82 301600.0 -174000.0 -2.17 -2.8211 -0.9961 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I04 compound treatment 310000.0 -123000.0 -1.35 326400.0 -149000.0 -1.86 -2.2704 -0.9876 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I05 mock treatment 411200.0 -22100.0 -0.24 433600.0 -41600.0 -0.52 -0.5389 -0.9395 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I06 mock treatment 401200.0 -32100.0 -0.35 427600.0 -47600.0 -0.59 -0.6693 -0.9685 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I07 compound treatment 333200.0 -100000.0 -1.1 367600.0 -108000.0 -1.35 -1.7264 -0.9948 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I08 compound treatment 293200.0 -140000.0 -1.53 320000.0 -155000.0 -1.94 -2.4571 -0.9932 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I09 compound treatment 378800.0 -54500.0 -0.6 435200.0 -40000.0 -0.5 -0.7756 -0.9961 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I10 compound treatment 136400.0 -297000.0 -3.25 123600.0 -352000.0 -4.4 -5.4079 -0.989 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I11 compound treatment 393600.0 -39700.0 -0.43 442400.0 -32800.0 -0.41 -0.5973 -0.9996 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I12 compound treatment 350400.0 -82900.0 -0.91 394000.0 -81200.0 -1.02 -1.3598 -0.9984 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I13 compound treatment 237200.0 -196000.0 -2.15 274000.0 -201000.0 -2.52 -3.2974 -0.9969 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I14 compound treatment 282800.0 -151000.0 -1.65 329600.0 -146000.0 -1.82 -2.4527 -0.9988 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I15 compound treatment 237200.0 -196000.0 -2.15 268400.0 -207000.0 -2.59 -3.347 -0.9957 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I16 compound treatment 159600.0 -274000.0 -3.0 163600.0 -312000.0 -3.9 -4.8746 -0.9916 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I17 compound treatment 161600.0 -272000.0 -2.98 218000.0 -257000.0 -3.22 -4.378 -0.9992 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I18 compound treatment 263600.0 -170000.0 -1.86 289200.0 -186000.0 -2.33 -2.9586 -0.9938 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I19 compound treatment 309200.0 -124000.0 -1.36 320800.0 -154000.0 -1.93 -2.3261 -0.9852 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I20 compound treatment 238000.0 -195000.0 -2.14 252400.0 -223000.0 -2.79 -3.4823 -0.9915 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I21 mock treatment 408000.0 -25300.0 -0.28 438800.0 -36400.0 -0.45 -0.5177 -0.9718 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I22 mock treatment 435600.0 2290.0 0.03 458000.0 -17200.0 -0.21 -0.1342 -0.6205 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I23 compound treatment 390400.0 -42900.0 -0.47 430000.0 -45200.0 -0.56 -0.7317 -0.9958 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 I24 compound treatment 426400.0 -6910.0 -0.08 456400.0 -18800.0 -0.23 -0.2196 -0.89 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J01 compound treatment 369600.0 -63700.0 -0.7 393200.0 -82000.0 -1.03 -1.2182 -0.9824 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J02 compound treatment 576400.0 143000.0 1.57 621600.0 146000.0 1.83 2.4027 0.997 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J03 compound treatment 314400.0 -119000.0 -1.3 351600.0 -124000.0 -1.55 -2.0135 -0.9964 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J04 compound treatment 506800.0 73500.0 0.8 507600.0 32400.0 0.41 0.8557 0.9497 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J05 mock treatment 433600.0 286.0 0.0 464400.0 -10800.0 -0.13 -0.0931 -0.6905 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J06 mock treatment 436800.0 3490.0 0.04 458400.0 -16800.0 -0.21 -0.1213 -0.5691 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J07 compound treatment 247200.0 -186000.0 -2.04 306400.0 -169000.0 -2.11 -2.9335 -0.9998 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J08 compound treatment 94000.0 -339000.0 -3.72 76800.0 -398000.0 -4.98 -6.1501 -0.9896 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J09 compound treatment 279200.0 -154000.0 -1.69 326800.0 -148000.0 -1.86 -2.5053 -0.9989 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J10 compound treatment 419200.0 -14100.0 -0.15 458800.0 -16400.0 -0.2 -0.2541 -0.9904 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J11 compound treatment 309600.0 -124000.0 -1.35 323600.0 -152000.0 -1.9 -2.2983 -0.9864 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J12 compound treatment 207600.0 -226000.0 -2.47 227600.0 -248000.0 -3.1 -3.9369 -0.9938 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J13 compound treatment 297600.0 -136000.0 -1.49 324800.0 -150000.0 -1.88 -2.3806 -0.9932 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J14 compound treatment 452400.0 19100.0 0.21 518800.0 43600.0 0.55 0.5336 0.9132 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J15 compound treatment 218800.0 -215000.0 -2.35 246800.0 -228000.0 -2.86 -3.6804 -0.9953 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J16 compound treatment 501200.0 67900.0 0.74 523200.0 48000.0 0.6 0.9503 0.9944 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J17 compound treatment 275600.0 -158000.0 -1.73 282400.0 -193000.0 -2.41 -2.9258 -0.9866 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J18 compound treatment 302400.0 -131000.0 -1.43 305200.0 -170000.0 -2.13 -2.5167 -0.9816 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J19 compound treatment 296000.0 -137000.0 -1.5 279200.0 -196000.0 -2.45 -2.7962 -0.9725 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J20 compound treatment 438400.0 5090.0 0.06 453200.0 -22000.0 -0.27 -0.1549 -0.5526 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J21 mock treatment 434000.0 686.0 0.01 490800.0 15600.0 0.2 0.1435 0.7337 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J22 mock treatment 424000.0 -9310.0 -0.1 490000.0 14800.0 0.19 0.059 0.2788 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J23 compound treatment 290800.0 -143000.0 -1.56 335200.0 -140000.0 -1.75 -2.3412 -0.9984 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 J24 compound treatment 599600.0 166000.0 1.82 660800.0 186000.0 2.32 2.929 0.9928 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K01 compound treatment 428800.0 -4510.0 -0.05 423200.0 -52000.0 -0.65 -0.4946 -0.7587 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K02 compound treatment 217600.0 -216000.0 -2.36 273600.0 -202000.0 -2.52 -3.4527 -0.9995 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K03 compound treatment 290800.0 -143000.0 -1.56 303600.0 -172000.0 -2.15 -2.6207 -0.9878 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K04 compound treatment 224800.0 -209000.0 -2.28 253200.0 -222000.0 -2.78 -3.5774 -0.9953 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K05 compound treatment 369600.0 -63700.0 -0.7 391600.0 -83600.0 -1.05 -1.2324 -0.9807 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K06 compound treatment 52400.0 -381000.0 -4.17 55600.0 -420000.0 -5.25 -6.6596 -0.9935 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K07 mock treatment 393200.0 -40100.0 -0.44 437600.0 -37600.0 -0.47 -0.6429 -0.9994 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K08 mock treatment 365600.0 -67700.0 -0.74 389200.0 -86000.0 -1.08 -1.2846 -0.9835 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K09 compound treatment 65200.0 -368000.0 -4.03 104800.0 -370000.0 -4.63 -6.1254 -0.9976 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K10 compound treatment 266800.0 -167000.0 -1.82 320800.0 -154000.0 -1.93 -2.6544 -0.9996 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K11 compound treatment 304800.0 -129000.0 -1.41 316400.0 -159000.0 -1.99 -2.3991 -0.9858 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K12 compound treatment 126000.0 -307000.0 -3.36 221200.0 -254000.0 -3.18 -4.6253 -0.9996 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K13 compound treatment 340800.0 -92500.0 -1.01 422800.0 -52400.0 -0.66 -1.1794 -0.9777 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K14 compound treatment 291600.0 -142000.0 -1.55 324000.0 -151000.0 -1.89 -2.4341 -0.9952 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K15 mock treatment 397600.0 -35700.0 -0.39 463200.0 -12000.0 -0.15 -0.3824 -0.9132 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K16 mock treatment 381200.0 -52100.0 -0.57 449600.0 -25600.0 -0.32 -0.6296 -0.9626 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K17 compound treatment 404000.0 -29300.0 -0.32 446000.0 -29200.0 -0.36 -0.485 -0.998 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K18 compound treatment 206400.0 -227000.0 -2.48 226400.0 -249000.0 -3.11 -3.9568 -0.9938 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K19 compound treatment 226800.0 -207000.0 -2.26 238400.0 -237000.0 -2.96 -3.6928 -0.9911 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K20 compound treatment 194800.0 -239000.0 -2.61 232400.0 -243000.0 -3.04 -3.9936 -0.9972 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K21 compound treatment 314400.0 -119000.0 -1.3 317600.0 -158000.0 -1.97 -2.3142 -0.9798 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K22 compound treatment 27600.0 -406000.0 -4.44 67200.0 -408000.0 -5.1 -6.749 -0.9976 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K23 mock treatment 499600.0 66300.0 0.73 537200.0 62000.0 0.78 1.0617 0.9994 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 K24 mock treatment 524000.0 90700.0 0.99 532800.0 57600.0 0.72 1.2117 0.9876 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L01 compound treatment 298800.0 -135000.0 -1.47 287200.0 -188000.0 -2.35 -2.7038 -0.9746 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L02 compound treatment 438000.0 4690.0 0.05 469200.0 -5970.0 -0.07 -0.0165 -0.1826 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L03 compound treatment 235600.0 -198000.0 -2.16 273600.0 -202000.0 -2.52 -3.3134 -0.9971 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L04 compound treatment 448000.0 14700.0 0.16 552400.0 77200.0 0.97 0.7966 0.8136 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L05 compound treatment 273600.0 -160000.0 -1.75 315600.0 -160000.0 -2.0 -2.6477 -0.9978 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L06 compound treatment 435600.0 2290.0 0.03 496800.0 21600.0 0.27 0.2089 0.7693 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L07 mock treatment 402800.0 -30500.0 -0.33 466400.0 -8770.0 -0.11 -0.3138 -0.8924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L08 mock treatment 414400.0 -18900.0 -0.21 487600.0 12400.0 0.16 -0.0365 -0.1412 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L09 compound treatment 354800.0 -78500.0 -0.86 388000.0 -87200.0 -1.09 -1.3788 -0.9931 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L10 compound treatment 408400.0 -24900.0 -0.27 474400.0 -773.0 -0.01 -0.1997 -0.7317 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L11 compound treatment 232400.0 -201000.0 -2.2 279200.0 -196000.0 -2.45 -3.2886 -0.9985 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L12 compound treatment 460000.0 26700.0 0.29 490400.0 15200.0 0.19 0.3413 0.9785 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L13 compound treatment 308400.0 -125000.0 -1.37 355200.0 -120000.0 -1.5 -2.0281 -0.9989 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L14 compound treatment 422000.0 -11300.0 -0.12 509600.0 34400.0 0.43 0.2168 0.484 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L15 mock treatment 438400.0 5090.0 0.06 502800.0 27600.0 0.35 0.2837 0.8106 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L16 mock treatment 425200.0 -8110.0 -0.09 477600.0 2430.0 0.03 -0.0414 -0.4406 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L17 compound treatment 271200.0 -162000.0 -1.78 316400.0 -159000.0 -1.99 -2.6592 -0.9984 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L18 compound treatment 479600.0 46300.0 0.51 527200.0 52000.0 0.65 0.8185 0.9924 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L19 compound treatment 278400.0 -155000.0 -1.7 301600.0 -174000.0 -2.17 -2.7344 -0.9926 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L20 compound treatment 423200.0 -10100.0 -0.11 441200.0 -34000.0 -0.42 -0.3787 -0.8626 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L21 compound treatment 263600.0 -170000.0 -1.86 275200.0 -200000.0 -2.5 -3.0824 -0.9893 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L22 compound treatment 546400.0 113000.0 1.24 631200.0 156000.0 1.95 2.2554 0.9759 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L23 mock treatment 503200.0 69900.0 0.77 514400.0 39200.0 0.49 0.888 0.9769 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 L24 mock treatment 533200.0 99900.0 1.09 582400.0 107000.0 1.34 1.7216 0.9949 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M01 compound treatment 200000.0 -233000.0 -2.55 210800.0 -264000.0 -3.31 -4.1444 -0.9919 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M02 compound treatment 160400.0 -273000.0 -2.99 257200.0 -218000.0 -2.73 -4.0406 -0.9989 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M03 compound treatment 228800.0 -205000.0 -2.24 253200.0 -222000.0 -2.78 -3.5464 -0.9943 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M04 compound treatment 248000.0 -185000.0 -2.03 282400.0 -193000.0 -2.41 -3.1395 -0.9963 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M05 compound treatment 203200.0 -230000.0 -2.52 211200.0 -264000.0 -3.3 -4.116 -0.9911 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M06 compound treatment 28800.0 -405000.0 -4.43 53200.0 -422000.0 -5.28 -6.8636 -0.9962 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M07 compound treatment 556000.0 123000.0 1.34 600800.0 126000.0 1.57 2.0608 0.997 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M08 compound treatment 208400.0 -225000.0 -2.46 216800.0 -258000.0 -3.23 -4.0263 -0.991 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M09 mock treatment 381200.0 -52100.0 -0.57 454000.0 -21200.0 -0.26 -0.5907 -0.9391 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M10 mock treatment 430800.0 -2510.0 -0.03 446800.0 -28400.0 -0.35 -0.2704 -0.7597 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M11 compound treatment 391200.0 -42100.0 -0.46 441600.0 -33600.0 -0.42 -0.623 -0.9989 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M12 compound treatment 285200.0 -148000.0 -1.62 331600.0 -144000.0 -1.8 -2.4164 -0.9987 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M13 mock treatment 356000.0 -77300.0 -0.85 467200.0 -7970.0 -0.1 -0.6691 -0.785 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M14 mock treatment 402000.0 -31300.0 -0.34 466800.0 -8370.0 -0.1 -0.3165 -0.8828 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M15 compound treatment 116800.0 -317000.0 -3.47 143600.0 -332000.0 -4.15 -5.3828 -0.996 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M16 compound treatment 287600.0 -146000.0 -1.6 310000.0 -165000.0 -2.07 -2.5889 -0.9919 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M17 compound treatment 247600.0 -186000.0 -2.03 258800.0 -216000.0 -2.71 -3.3513 -0.9901 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M18 compound treatment 340000.0 -93300.0 -1.02 359200.0 -116000.0 -1.45 -1.7481 -0.9853 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M19 compound treatment 273600.0 -160000.0 -1.75 311200.0 -164000.0 -2.05 -2.6866 -0.9969 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M20 compound treatment 119200.0 -314000.0 -3.44 172400.0 -303000.0 -3.79 -5.1095 -0.9988 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M21 compound treatment 332400.0 -101000.0 -1.1 336400.0 -139000.0 -1.74 -2.0085 -0.9762 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M22 compound treatment 305600.0 -128000.0 -1.4 347200.0 -128000.0 -1.6 -2.1205 -0.9977 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M23 compound treatment 258800.0 -175000.0 -1.91 252000.0 -223000.0 -2.79 -3.3248 -0.9829 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 M24 compound treatment 10400.0 -423000.0 -4.63 14400.0 -461000.0 -5.76 -7.3491 -0.9941 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N01 compound treatment 408000.0 -25300.0 -0.28 395200.0 -80000.0 -1.0 -0.9032 -0.8703 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N02 compound treatment 554000.0 121000.0 1.32 596000.0 121000.0 1.51 2.0029 0.9978 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N03 compound treatment 365200.0 -68100.0 -0.75 410400.0 -64800.0 -0.81 -1.1002 -0.9991 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N04 compound treatment 464000.0 30700.0 0.34 487200.0 12000.0 0.15 0.3439 0.9343 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N05 compound treatment 241200.0 -192000.0 -2.1 339600.0 -136000.0 -1.7 -2.6863 -0.9943 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N06 compound treatment 493200.0 59900.0 0.66 548400.0 73200.0 0.92 1.1112 0.9866 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N07 compound treatment 349200.0 -84100.0 -0.92 365600.0 -110000.0 -1.37 -1.6202 -0.9813 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N08 compound treatment 500400.0 67100.0 0.73 544400.0 69200.0 0.87 1.1316 0.9967 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N09 mock treatment 412800.0 -20500.0 -0.22 448000.0 -27200.0 -0.34 -0.3991 -0.9798 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N10 mock treatment 462000.0 28700.0 0.31 464800.0 -10400.0 -0.13 0.1304 0.3836 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N11 compound treatment 254400.0 -179000.0 -1.96 294000.0 -181000.0 -2.27 -2.9874 -0.9974 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N12 compound treatment 548000.0 115000.0 1.26 590000.0 115000.0 1.44 1.9034 0.9978 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N13 mock treatment 436800.0 3490.0 0.04 501200.0 26000.0 0.33 0.2572 0.7846 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N14 mock treatment 460000.0 26700.0 0.29 473600.0 -1570.0 -0.02 0.1927 0.658 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N15 compound treatment 269600.0 -164000.0 -1.79 262000.0 -213000.0 -2.67 -3.1527 -0.9813 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N16 compound treatment 548400.0 115000.0 1.26 569600.0 94400.0 1.18 1.7261 0.9995 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N17 compound treatment 277200.0 -156000.0 -1.71 293600.0 -182000.0 -2.27 -2.8144 -0.9902 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N18 compound treatment 476400.0 43100.0 0.47 528400.0 53200.0 0.67 0.8043 0.9858 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N19 compound treatment 263600.0 -170000.0 -1.86 282000.0 -193000.0 -2.42 -3.0223 -0.9916 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N20 compound treatment 474000.0 40700.0 0.45 524400.0 49200.0 0.62 0.7503 0.9874 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N21 compound treatment 306800.0 -127000.0 -1.39 310400.0 -165000.0 -2.06 -2.4367 -0.9813 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N22 compound treatment 467200.0 33900.0 0.37 475200.0 26.7 0.0 0.2626 0.7077 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N23 compound treatment 323600.0 -110000.0 -1.2 345600.0 -130000.0 -1.62 -1.9953 -0.9891 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 N24 compound treatment 581200.0 148000.0 1.62 691200.0 216000.0 2.7 3.0554 0.97 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O01 compound treatment 570000.0 137000.0 1.5 632400.0 157000.0 1.97 2.4487 0.9909 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O02 compound treatment 278800.0 -155000.0 -1.69 308400.0 -167000.0 -2.09 -2.6711 -0.9946 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O03 compound treatment 373600.0 -59700.0 -0.65 403200.0 -72000.0 -0.9 -1.0988 -0.9877 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O04 compound treatment 257600.0 -176000.0 -1.92 268400.0 -207000.0 -2.59 -3.189 -0.9894 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O05 compound treatment 174400.0 -259000.0 -2.83 188400.0 -287000.0 -3.59 -4.5406 -0.9932 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O06 compound treatment 616000.0 183000.0 2.0 594000.0 119000.0 1.49 2.4652 0.9893 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O07 compound treatment 332000.0 -101000.0 -1.11 334000.0 -141000.0 -1.77 -2.0329 -0.9749 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O08 compound treatment 290400.0 -143000.0 -1.56 282400.0 -193000.0 -2.41 -2.8113 -0.9781 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O09 compound treatment 203200.0 -230000.0 -2.52 243600.0 -232000.0 -2.9 -3.8295 -0.9976 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O10 compound treatment 313600.0 -120000.0 -1.31 351200.0 -124000.0 -1.55 -2.0232 -0.9965 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O11 mock treatment 473600.0 40300.0 0.44 520400.0 45200.0 0.57 0.7119 0.9924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O12 mock treatment 459600.0 26300.0 0.29 491200.0 16000.0 0.2 0.3452 0.9844 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O13 compound treatment 277200.0 -156000.0 -1.71 279600.0 -196000.0 -2.45 -2.9382 -0.9847 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O14 compound treatment 194800.0 -239000.0 -2.61 271200.0 -204000.0 -2.55 -3.6505 -0.9999 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O15 compound treatment 371600.0 -61700.0 -0.68 391600.0 -83600.0 -1.05 -1.2169 -0.9777 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O16 compound treatment 203200.0 -230000.0 -2.52 225600.0 -250000.0 -3.12 -3.9887 -0.9944 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O17 compound treatment 276800.0 -157000.0 -1.71 323600.0 -152000.0 -1.9 -2.5522 -0.9987 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O18 compound treatment 168800.0 -265000.0 -2.9 198800.0 -276000.0 -3.46 -4.492 -0.9961 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O19 compound treatment 276000.0 -157000.0 -1.72 301200.0 -174000.0 -2.18 -2.7565 -0.9933 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O20 compound treatment 297200.0 -136000.0 -1.49 315600.0 -160000.0 -2.0 -2.465 -0.9897 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O21 compound treatment 299200.0 -134000.0 -1.47 299600.0 -176000.0 -2.2 -2.591 -0.9809 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O22 compound treatment 370800.0 -62500.0 -0.68 434000.0 -41200.0 -0.51 -0.8481 -0.9902 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O23 compound treatment 248800.0 -185000.0 -2.02 358800.0 -116000.0 -1.46 -2.4577 -0.987 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 O24 compound treatment 361200.0 -72100.0 -0.79 403600.0 -71600.0 -0.9 -1.1913 -0.998 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P01 compound treatment 464400.0 31100.0 0.34 468800.0 -6370.0 -0.08 0.1843 0.5273 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P02 compound treatment 687200.0 254000.0 2.78 710000.0 235000.0 2.94 4.0423 0.9996 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P03 compound treatment 410000.0 -23300.0 -0.26 384000.0 -91200.0 -1.14 -0.9868 -0.8445 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P04 compound treatment 561600.0 128000.0 1.4 616400.0 141000.0 1.77 2.2422 0.9936 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P05 compound treatment 11600.0 -422000.0 -4.62 13200.0 -462000.0 -5.78 -7.3505 -0.9938 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P06 compound treatment 665200.0 232000.0 2.54 639600.0 164000.0 2.06 3.2494 0.9945 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P07 compound treatment 387600.0 -45700.0 -0.5 444400.0 -30800.0 -0.38 -0.6261 -0.9916 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P08 compound treatment 548800.0 115000.0 1.26 581200.0 106000.0 1.33 1.8318 0.9997 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P09 compound treatment 298400.0 -135000.0 -1.48 337600.0 -138000.0 -1.72 -2.2612 -0.9971 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P10 compound treatment 439600.0 6290.0 0.07 469600.0 -5570.0 -0.07 -6.0E-4 -0.0063 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P11 mock treatment 607200.0 174000.0 1.9 633600.0 158000.0 1.98 2.7473 0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P12 mock treatment 535600.0 102000.0 1.12 619600.0 144000.0 1.81 2.0692 0.9736 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P13 compound treatment 370800.0 -62500.0 -0.68 399600.0 -75600.0 -0.95 -1.1523 -0.9874 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P14 compound treatment 642800.0 209000.0 2.29 679200.0 204000.0 2.55 3.4262 0.9986 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P15 compound treatment 325200.0 -108000.0 -1.18 374800.0 -100000.0 -1.26 -1.7247 -0.9996 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P16 compound treatment 604400.0 171000.0 1.87 653600.0 178000.0 2.23 2.9025 0.9962 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P17 compound treatment 322400.0 -111000.0 -1.21 362800.0 -112000.0 -1.41 -1.8525 -0.9974 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P18 compound treatment 620800.0 187000.0 2.05 689600.0 214000.0 2.68 3.3478 0.9913 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P19 compound treatment 284800.0 -149000.0 -1.63 319200.0 -156000.0 -1.95 -2.5292 -0.9959 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P20 compound treatment 517600.0 84300.0 0.92 542000.0 66800.0 0.84 1.2435 0.9988 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P21 compound treatment 382400.0 -50900.0 -0.56 432000.0 -43200.0 -0.54 -0.776 -0.9999 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P22 compound treatment 633600.0 200000.0 2.19 712400.0 237000.0 2.97 3.6486 0.9889 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P23 compound treatment 370800.0 -62500.0 -0.68 396800.0 -78400.0 -0.98 -1.1771 -0.9846 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2102 P24 compound treatment 822000.0 389000.0 4.26 870000.0 395000.0 4.94 6.5009 0.9973 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A01 compound treatment 483600.0 -13200.0 -0.14 513200.0 -35900.0 -0.45 -0.4198 -0.8897 3070297 PK04_103001 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A02 compound treatment 485200.0 -11600.0 -0.13 482800.0 -66300.0 -0.83 -0.6763 -0.806 3189402 PK04_103002 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A03 compound treatment 282400.0 -214000.0 -2.35 283600.0 -266000.0 -3.32 -4.008 -0.9856 3070298 PK04_103003 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A04 compound treatment 657600.0 161000.0 1.76 629600.0 80500.0 1.01 1.9567 0.9648 3189403 PK04_103004 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A05 compound treatment 618800.0 122000.0 1.34 624800.0 75700.0 0.95 1.6139 0.9858 3070299 PK04_103005 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A06 compound treatment 533200.0 36400.0 0.4 556400.0 7280.0 0.09 0.3462 0.8469 3189404 PK04_103006 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A07 compound treatment 443200.0 -53600.0 -0.59 444000.0 -105000.0 -1.31 -1.3446 -0.9339 3070300 PK04_103007 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A08 compound treatment 506800.0 10000.0 0.11 514000.0 -35100.0 -0.44 -0.2331 -0.515 3189405 PK04_103008 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A09 compound treatment 457200.0 -39600.0 -0.43 465600.0 -83500.0 -1.04 -1.0452 -0.9242 3189406 PK04_103009 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A10 compound treatment 564800.0 68000.0 0.74 626800.0 77700.0 0.97 1.2135 0.9914 3070355 PK04_103010 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A11 compound treatment 563200.0 66400.0 0.73 605200.0 56100.0 0.7 1.0101 0.9998 3189407 PK04_103011 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A12 compound treatment 552000.0 55200.0 0.6 579600.0 30500.0 0.38 0.697 0.9753 3189408 PK04_103012 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A13 mock treatment 592000.0 95200.0 1.04 604800.0 55700.0 0.7 1.2295 0.9808 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A14 mock treatment 580400.0 83600.0 0.92 603200.0 54100.0 0.68 1.1255 0.9889 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A15 compound treatment 228000.0 -269000.0 -2.94 228800.0 -320000.0 -4.01 -4.9138 -0.9885 3070356 PK04_103013 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A16 compound treatment 563600.0 66800.0 0.73 593600.0 44500.0 0.56 0.9106 0.9909 3189409 PK04_103014 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A17 compound treatment 158800.0 -338000.0 -3.7 158400.0 -391000.0 -4.89 -6.0722 -0.9906 3070357 PK04_103015 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A18 compound treatment 561200.0 64400.0 0.71 560000.0 10900.0 0.14 0.5949 0.8283 3189410 PK04_103016 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A19 compound treatment 442000.0 -54800.0 -0.6 469200.0 -79900.0 -1.0 -1.131 -0.9702 3070358 PK04_103017 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A20 compound treatment 489200.0 -7600.0 -0.08 489600.0 -59500.0 -0.74 -0.5852 -0.7813 3189411 PK04_103018 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A21 compound treatment 603600.0 107000.0 1.17 661600.0 112000.0 1.41 1.8216 0.9958 3070359 PK04_103019 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A22 compound treatment 498000.0 1200.0 0.01 519200.0 -29900.0 -0.37 -0.2553 -0.6819 3189412 PK04_103020 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A23 compound treatment 674800.0 178000.0 1.95 688000.0 139000.0 1.74 2.6063 0.9983 3070360 PK04_103021 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 A24 compound treatment 486800.0 -10000.0 -0.11 520000.0 -29100.0 -0.36 -0.3349 -0.8808 3189413 PK04_103022 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B01 compound treatment 660400.0 164000.0 1.79 819200.0 270000.0 3.38 3.6551 0.956 3189525 PK04_103023 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B02 compound treatment 332400.0 -164000.0 -1.8 418400.0 -131000.0 -1.63 -2.4288 -0.9988 3070361 PK04_103024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B03 compound treatment 400400.0 -96400.0 -1.06 512000.0 -37100.0 -0.46 -1.0746 -0.9319 3189526 PK04_103025 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B04 compound treatment 480800.0 -16000.0 -0.18 582800.0 33700.0 0.42 0.174 0.3814 3189527 PK04_103026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B05 compound treatment 562400.0 65600.0 0.72 628400.0 79300.0 0.99 1.209 0.9875 3070362 PK04_103027 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B06 compound treatment 354000.0 -143000.0 -1.56 352400.0 -197000.0 -2.46 -2.8452 -0.9761 3189528 PK04_103028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B07 compound treatment 565600.0 68800.0 0.75 645600.0 96500.0 1.21 1.3859 0.9743 3070363 PK04_103029 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B08 compound treatment 516000.0 19200.0 0.21 584800.0 35700.0 0.45 0.4642 0.941 3189529 PK04_103030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B09 compound treatment 336400.0 -160000.0 -1.76 416800.0 -132000.0 -1.65 -2.412 -0.9996 3189530 PK04_103031 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B10 compound treatment 548400.0 51600.0 0.56 598800.0 49700.0 0.62 0.8389 0.9989 3070364 PK04_103032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B11 compound treatment 401200.0 -95600.0 -1.05 432800.0 -116000.0 -1.45 -1.7688 -0.987 3189531 PK04_103033 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B12 compound treatment 504000.0 7200.0 0.08 566000.0 16900.0 0.21 0.2051 0.9098 3189532 PK04_103034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B13 mock treatment 533600.0 36800.0 0.4 590000.0 40900.0 0.51 0.6465 0.993 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B14 mock treatment 569600.0 72800.0 0.8 571600.0 22500.0 0.28 0.7625 0.9021 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B15 compound treatment 397200.0 -99600.0 -1.09 476000.0 -73100.0 -0.91 -1.4177 -0.9962 3070365 PK04_103035 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B16 compound treatment 508800.0 12000.0 0.13 576400.0 27300.0 0.34 0.3342 0.914 3189533 PK04_103036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B17 compound treatment 539200.0 42400.0 0.46 600000.0 50900.0 0.64 0.7783 0.988 3070366 PK04_103037 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B18 compound treatment 489600.0 -7200.0 -0.08 584000.0 34900.0 0.44 0.2527 0.5701 3189534 PK04_103038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B19 compound treatment 570400.0 73600.0 0.81 587200.0 38100.0 0.48 0.9066 0.9685 3189535 PK04_103039 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B20 compound treatment 528800.0 32000.0 0.35 580400.0 31300.0 0.39 0.5244 0.9985 3070367 PK04_103040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B21 compound treatment 587600.0 90800.0 0.99 622000.0 72900.0 0.91 1.3475 0.9991 3189536 PK04_103041 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B22 compound treatment 563600.0 66800.0 0.73 622000.0 72900.0 0.91 1.1617 0.994 3189537 PK04_103042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B23 compound treatment 699600.0 203000.0 2.22 735200.0 186000.0 2.33 3.2158 0.9997 3070368 PK04_103043 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 B24 compound treatment 572400.0 75600.0 0.83 603200.0 54100.0 0.68 1.0636 0.995 3189538 PK04_103044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C01 compound treatment 636800.0 140000.0 1.53 674400.0 125000.0 1.57 2.1919 0.9999 3070369 PK04_103045 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C02 compound treatment 564800.0 68000.0 0.74 581600.0 32500.0 0.41 0.8137 0.9594 3189539 PK04_103046 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C03 compound treatment 402800.0 -94000.0 -1.03 374400.0 -175000.0 -2.19 -2.2729 -0.941 3189540 PK04_103047 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C04 compound treatment 436000.0 -60800.0 -0.67 455200.0 -93900.0 -1.17 -1.3013 -0.9638 3070370 PK04_103048 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C05 compound treatment 518000.0 21200.0 0.23 496400.0 -52700.0 -0.66 -0.302 -0.4321 3189541 PK04_103049 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C06 compound treatment 546400.0 49600.0 0.54 562800.0 13700.0 0.17 0.505 0.8869 3189542 PK04_103050 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C07 compound treatment 537600.0 40800.0 0.45 550000.0 884.0 0.01 0.3237 0.7244 3070371 PK04_103051 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C08 compound treatment 506400.0 9600.0 0.11 548000.0 -1120.0 -0.01 0.0645 0.6079 3189543 PK04_103052 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C09 compound treatment 310000.0 -187000.0 -2.05 320800.0 -228000.0 -2.86 -3.4654 -0.9866 3070372 PK04_103053 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C10 compound treatment 469600.0 -27200.0 -0.3 531600.0 -17500.0 -0.22 -0.3655 -0.9886 3189544 PK04_103054 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C11 mock treatment 501200.0 4400.0 0.05 546400.0 -2720.0 -0.03 0.01 0.1704 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C12 mock treatment 479600.0 -17200.0 -0.19 549200.0 83.9 0.0 -0.1324 -0.7032 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C13 compound treatment 398800.0 -98000.0 -1.07 457600.0 -91500.0 -1.14 -1.5681 -0.9995 3189545 PK04_103055 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C14 compound treatment 320400.0 -176000.0 -1.93 346800.0 -202000.0 -2.53 -3.1549 -0.9911 3189546 PK04_103056 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C15 mock treatment 468400.0 -28400.0 -0.31 523200.0 -25900.0 -0.32 -0.4491 -0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C16 mock treatment 499600.0 2800.0 0.03 538000.0 -11100.0 -0.14 -0.0766 -0.5382 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C17 compound treatment 255600.0 -241000.0 -2.64 270000.0 -279000.0 -3.49 -4.3358 -0.9905 3070427 PK04_103057 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C18 compound treatment 360000.0 -137000.0 -1.5 392000.0 -157000.0 -1.96 -2.4486 -0.991 3189660 PK04_103058 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C19 compound treatment 166400.0 -330000.0 -3.62 166400.0 -383000.0 -4.79 -5.9426 -0.9905 3070428 PK04_103059 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C20 compound treatment 350800.0 -146000.0 -1.6 374000.0 -175000.0 -2.19 -2.679 -0.988 3189661 PK04_103060 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C21 compound treatment 287200.0 -210000.0 -2.29 316800.0 -232000.0 -2.91 -3.6773 -0.9932 3189662 PK04_103061 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C22 compound treatment 509200.0 12400.0 0.14 560800.0 11700.0 0.15 0.1993 0.9993 3070429 PK04_103062 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C23 compound treatment 550400.0 53600.0 0.59 619200.0 70100.0 0.88 1.0348 0.981 3189663 PK04_103063 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 C24 compound treatment 574000.0 77200.0 0.85 604800.0 55700.0 0.7 1.0901 0.9954 3189664 PK04_103064 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D01 compound treatment 294400.0 -202000.0 -2.22 392000.0 -157000.0 -1.96 -2.9565 -0.9982 3070430 PK04_103065 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D02 compound treatment 379200.0 -118000.0 -1.29 610400.0 61300.0 0.77 -0.3685 -0.2459 3189665 PK04_103066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D03 compound treatment 537600.0 40800.0 0.45 655600.0 106000.0 1.33 1.2576 0.8953 3070431 PK04_103067 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D04 compound treatment 463200.0 -33600.0 -0.37 515200.0 -33900.0 -0.42 -0.5601 -0.9975 3189666 PK04_103068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D05 compound treatment 491200.0 -5600.0 -0.06 544800.0 -4320.0 -0.05 -0.0815 -0.998 3189667 PK04_103069 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D06 compound treatment 434800.0 -62000.0 -0.68 518800.0 -30300.0 -0.38 -0.7481 -0.9621 3189668 PK04_103070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D07 compound treatment 465600.0 -31200.0 -0.34 513200.0 -35900.0 -0.45 -0.5592 -0.9909 3070432 PK04_103071 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D08 compound treatment 472400.0 -24400.0 -0.27 516800.0 -32300.0 -0.4 -0.4747 -0.9798 3189669 PK04_103072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D09 compound treatment 292800.0 -204000.0 -2.23 350000.0 -199000.0 -2.49 -3.3403 -0.9985 3070433 PK04_103073 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D10 compound treatment 432800.0 -64000.0 -0.7 524000.0 -25100.0 -0.31 -0.7176 -0.9345 3189670 PK04_103074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D11 mock treatment 454400.0 -42400.0 -0.46 519200.0 -29900.0 -0.37 -0.5928 -0.9943 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D12 mock treatment 438800.0 -58000.0 -0.64 525200.0 -23900.0 -0.3 -0.6606 -0.941 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D13 compound treatment 299600.0 -197000.0 -2.16 335200.0 -214000.0 -2.68 -3.4185 -0.9944 3189671 PK04_103075 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D14 compound treatment 455600.0 -41200.0 -0.45 509600.0 -39500.0 -0.49 -0.6684 -0.999 3070434 PK04_103076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D15 mock treatment 481200.0 -15600.0 -0.17 532800.0 -16300.0 -0.2 -0.2651 -0.9961 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D16 mock treatment 481600.0 -15200.0 -0.17 549200.0 83.9 0.0 -0.1169 -0.7026 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D17 compound treatment 198000.0 -299000.0 -3.27 222800.0 -326000.0 -4.08 -5.1992 -0.994 3189672 PK04_103077 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D18 compound treatment 448400.0 -48400.0 -0.53 489200.0 -59900.0 -0.75 -0.9046 -0.9856 3189673 PK04_103078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D19 compound treatment 369200.0 -128000.0 -1.4 422400.0 -127000.0 -1.58 -2.1085 -0.998 3070435 PK04_103079 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D20 compound treatment 487200.0 -9600.0 -0.11 548400.0 -716.0 -0.01 -0.0807 -0.7646 3189674 PK04_103080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D21 compound treatment 488800.0 -8000.0 -0.09 535200.0 -13900.0 -0.17 -0.185 -0.9495 3189675 PK04_103081 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D22 compound treatment 424800.0 -72000.0 -0.79 482400.0 -66700.0 -0.83 -1.1474 -0.9996 3070436 PK04_103082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D23 compound treatment 575200.0 78400.0 0.86 596800.0 47700.0 0.6 1.0287 0.9842 3189676 PK04_103083 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 D24 compound treatment 578000.0 81200.0 0.89 622000.0 72900.0 0.91 1.2732 0.9999 3070437 PK04_103084 CN1CCC(=CC1C2CC2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E01 mock treatment 605600.0 109000.0 1.19 672400.0 123000.0 1.54 1.9326 0.9919 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E02 mock treatment 586800.0 90000.0 0.99 584000.0 34900.0 0.44 1.0053 0.9328 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E03 compound treatment 499600.0 2800.0 0.03 568000.0 18900.0 0.24 0.1887 0.7923 3189677 PK04_103085 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E04 compound treatment 517200.0 20400.0 0.22 551200.0 2080.0 0.03 0.1764 0.7843 3070438 PK04_103086 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E05 compound treatment 477600.0 -19200.0 -0.21 528400.0 -20700.0 -0.26 -0.3319 -0.9946 3189678 PK04_103087 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E06 compound treatment 514000.0 17200.0 0.19 562400.0 13300.0 0.17 0.2506 0.998 3189679 PK04_103088 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E07 compound treatment 484800.0 -12000.0 -0.13 500800.0 -48300.0 -0.6 -0.5202 -0.8412 3189680 PK04_103089 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E08 compound treatment 441600.0 -55200.0 -0.6 446800.0 -102000.0 -1.28 -1.3322 -0.9414 3070490 PK04_103090 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E09 mock treatment 470800.0 -26000.0 -0.28 498000.0 -51100.0 -0.64 -0.6533 -0.9336 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E10 mock treatment 471200.0 -25600.0 -0.28 512400.0 -36700.0 -0.46 -0.5229 -0.972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E11 compound treatment 103200.0 -394000.0 -4.31 86000.0 -463000.0 -5.79 -7.1429 -0.9894 3187704 PK04_103091 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E12 compound treatment 332800.0 -164000.0 -1.8 389200.0 -160000.0 -2.0 -2.6839 -0.9986 3070491 PK04_103092 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E13 compound treatment 220400.0 -276000.0 -3.03 222800.0 -326000.0 -4.08 -5.0257 -0.9892 3187705 PK04_103093 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E14 compound treatment 230000.0 -267000.0 -2.92 276800.0 -272000.0 -3.41 -4.4739 -0.9971 3187706 PK04_103094 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E15 compound treatment 534400.0 37600.0 0.41 550400.0 1280.0 0.02 0.3025 0.7341 3070492 PK04_103095 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E16 compound treatment 510000.0 13200.0 0.14 550400.0 1280.0 0.02 0.1136 0.7809 3187707 PK04_103096 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E17 mock treatment 471600.0 -25200.0 -0.28 495600.0 -53500.0 -0.67 -0.6684 -0.9232 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E18 mock treatment 470800.0 -26000.0 -0.28 518000.0 -31100.0 -0.39 -0.4765 -0.9882 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E19 compound treatment 134800.0 -362000.0 -3.96 138000.0 -411000.0 -5.14 -6.4384 -0.9917 3070493 PK04_103097 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E20 compound treatment 409200.0 -87600.0 -0.96 458000.0 -91100.0 -1.14 -1.484 -0.9963 3187708 PK04_103098 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E21 compound treatment 222000.0 -275000.0 -3.01 248400.0 -301000.0 -3.76 -4.7869 -0.9939 3187709 PK04_103099 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E22 compound treatment 414800.0 -82000.0 -0.9 432000.0 -117000.0 -1.46 -1.6706 -0.9724 3070494 PK04_103100 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E23 compound treatment 564000.0 67200.0 0.74 592800.0 43700.0 0.55 0.9066 0.9893 3187710 PK04_103101 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 E24 compound treatment 627600.0 131000.0 1.43 739600.0 190000.0 2.38 2.6972 0.9704 3187711 PK04_103102 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F01 mock treatment 463200.0 -33600.0 -0.37 624000.0 74900.0 0.94 0.4021 0.3996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F02 mock treatment 452400.0 -44400.0 -0.49 542000.0 -7120.0 -0.09 -0.4067 -0.8229 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F03 compound treatment 416400.0 -80400.0 -0.88 545600.0 -3520.0 -0.04 -0.6536 -0.7415 3070495 PK04_103103 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F04 compound treatment 383600.0 -113000.0 -1.24 504000.0 -45100.0 -0.56 -1.2754 -0.9365 3187712 PK04_103104 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F05 compound treatment 314000.0 -183000.0 -2.0 376800.0 -172000.0 -2.16 -2.9392 -0.9993 3070496 PK04_103105 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F06 compound treatment 478000.0 -18800.0 -0.21 571600.0 22500.0 0.28 0.0533 0.1529 3187713 PK04_103106 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F07 compound treatment 490000.0 -6800.0 -0.07 549200.0 83.9 0.0 -0.0519 -0.6971 3070497 PK04_103107 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F08 compound treatment 464400.0 -32400.0 -0.35 540000.0 -9120.0 -0.11 -0.3315 -0.8895 3187714 PK04_103108 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F09 mock treatment 422800.0 -74000.0 -0.81 535600.0 -13500.0 -0.17 -0.6925 -0.8366 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F10 mock treatment 434800.0 -62000.0 -0.68 525600.0 -23500.0 -0.29 -0.688 -0.9299 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F11 compound treatment 464800.0 -32000.0 -0.35 476000.0 -73100.0 -0.91 -0.8943 -0.9133 3187715 PK04_103109 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F12 compound treatment 446000.0 -50800.0 -0.56 474800.0 -74300.0 -0.93 -1.0505 -0.9699 3070498 PK04_103110 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F13 compound treatment 84400.0 -412000.0 -4.52 82800.0 -466000.0 -5.83 -7.3168 -0.992 3187716 PK04_103111 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F14 compound treatment 452000.0 -44800.0 -0.49 538000.0 -11100.0 -0.14 -0.4452 -0.8731 3070499 PK04_103112 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F15 compound treatment 302400.0 -194000.0 -2.13 342000.0 -207000.0 -2.59 -3.3367 -0.9952 3187717 PK04_103113 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F16 compound treatment 509600.0 12800.0 0.14 506400.0 -42700.0 -0.53 -0.2787 -0.5045 3187718 PK04_103114 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F17 mock treatment 497600.0 800.0 0.01 554400.0 5280.0 0.07 0.0529 0.7939 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F18 mock treatment 482800.0 -14000.0 -0.15 529600.0 -19500.0 -0.24 -0.281 -0.9749 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F19 compound treatment 419600.0 -77200.0 -0.85 499600.0 -49500.0 -0.62 -1.0356 -0.9883 3070500 PK04_103115 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F20 compound treatment 434800.0 -62000.0 -0.68 482800.0 -66300.0 -0.83 -1.0665 -0.9951 3187719 PK04_103116 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F21 compound treatment 240000.0 -257000.0 -2.81 254400.0 -295000.0 -3.69 -4.5945 -0.9911 3070501 PK04_103117 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F22 compound treatment 370000.0 -127000.0 -1.39 400400.0 -149000.0 -1.86 -2.2969 -0.9896 3187720 PK04_103118 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F23 compound treatment 250000.0 -247000.0 -2.7 257600.0 -292000.0 -3.65 -4.4888 -0.9891 3187721 PK04_103119 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 F24 compound treatment 632400.0 136000.0 1.48 620800.0 71700.0 0.9 1.6838 0.9708 3070502 PK04_103120 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G01 compound treatment 285600.0 -211000.0 -2.31 316800.0 -232000.0 -2.91 -3.6896 -0.9936 3187722 PK04_103121 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G02 compound treatment 473200.0 -23600.0 -0.26 493200.0 -55900.0 -0.7 -0.6772 -0.9084 3187723 PK04_103122 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G03 mock treatment 501200.0 4400.0 0.05 559200.0 10100.0 0.13 0.1232 0.9129 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G04 mock treatment 491600.0 -5200.0 -0.06 532400.0 -16700.0 -0.21 -0.1881 -0.8681 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G05 compound treatment 240800.0 -256000.0 -2.8 234400.0 -315000.0 -3.94 -4.7652 -0.9862 3070503 PK04_103123 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G06 compound treatment 338000.0 -159000.0 -1.74 369600.0 -180000.0 -2.25 -2.817 -0.992 3187724 PK04_103124 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G07 compound treatment 276400.0 -220000.0 -2.41 309600.0 -240000.0 -3.0 -3.8245 -0.9943 3070504 PK04_103125 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G08 compound treatment 306400.0 -190000.0 -2.08 317200.0 -232000.0 -2.9 -3.5251 -0.9869 3187725 PK04_103126 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G09 compound treatment 426800.0 -70000.0 -0.77 440400.0 -109000.0 -1.36 -1.5034 -0.9632 3187726 PK04_103127 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G10 compound treatment 451200.0 -45600.0 -0.5 498400.0 -50700.0 -0.63 -0.8016 -0.993 3070543 PK04_103128 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G11 compound treatment 431600.0 -65200.0 -0.71 477600.0 -71500.0 -0.89 -1.1372 -0.9938 3187727 PK04_103129 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G12 compound treatment 136800.0 -360000.0 -3.94 144000.0 -405000.0 -5.07 -6.3698 -0.9923 3187844 PK04_103130 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G13 compound treatment 421200.0 -75600.0 -0.83 483200.0 -65900.0 -0.82 -1.1682 -1.0 3070544 PK04_103131 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G14 compound treatment 294400.0 -202000.0 -2.22 306800.0 -242000.0 -3.03 -3.7099 -0.9882 3187845 PK04_103132 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G15 compound treatment 400000.0 -96800.0 -1.06 445200.0 -104000.0 -1.3 -1.6684 -0.9949 3070545 PK04_103133 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G16 compound treatment 579200.0 82400.0 0.9 635200.0 86100.0 1.08 1.3992 0.9961 3187846 PK04_103134 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G17 compound treatment 360000.0 -137000.0 -1.5 380800.0 -168000.0 -2.11 -2.5476 -0.9861 3070546 PK04_103135 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G18 compound treatment 432400.0 -64400.0 -0.71 448400.0 -101000.0 -1.26 -1.3893 -0.9624 3187847 PK04_103136 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G19 mock treatment 471200.0 -25600.0 -0.28 520800.0 -28300.0 -0.35 -0.4486 -0.9933 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G20 mock treatment 478800.0 -18000.0 -0.2 512000.0 -37100.0 -0.46 -0.4676 -0.9272 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G21 compound treatment 515200.0 18400.0 0.2 560800.0 11700.0 0.15 0.2458 0.9876 3070547 PK04_103137 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G22 compound treatment 521600.0 24800.0 0.27 561600.0 12500.0 0.16 0.3024 0.9655 3187848 PK04_103138 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G23 compound treatment 546000.0 49200.0 0.54 534000.0 -15100.0 -0.19 0.2472 0.4331 3070548 PK04_103139 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 G24 compound treatment 648800.0 152000.0 1.66 646800.0 97700.0 1.22 2.0407 0.9884 3187849 PK04_103140 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H01 compound treatment 355200.0 -142000.0 -1.55 501200.0 -47900.0 -0.6 -1.5201 -0.9145 3070549 PK04_103141 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H02 compound treatment 400800.0 -96000.0 -1.05 518000.0 -31100.0 -0.39 -1.0184 -0.9086 3187850 PK04_103142 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H03 mock treatment 456400.0 -40400.0 -0.44 521600.0 -27500.0 -0.34 -0.5561 -0.9923 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H04 mock treatment 456000.0 -40800.0 -0.45 547600.0 -1520.0 -0.02 -0.3293 -0.7365 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H05 compound treatment 384800.0 -112000.0 -1.23 480000.0 -69100.0 -0.86 -1.4784 -0.9853 3187851 PK04_103143 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H06 compound treatment 483600.0 -13200.0 -0.14 550000.0 884.0 0.01 -0.0944 -0.6511 3187852 PK04_103144 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H07 compound treatment 494400.0 -2400.0 -0.03 538400.0 -10700.0 -0.13 -0.1133 -0.83 3070550 PK04_103145 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H08 compound treatment 437200.0 -59600.0 -0.65 546400.0 -2720.0 -0.03 -0.4855 -0.7429 3187853 PK04_103146 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H09 compound treatment 437600.0 -59200.0 -0.65 507600.0 -41500.0 -0.52 -0.8255 -0.994 3070551 PK04_103147 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H10 compound treatment 384400.0 -112000.0 -1.23 438400.0 -111000.0 -1.38 -1.8493 -0.9983 3070552 PK04_103148 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H11 compound treatment 352800.0 -144000.0 -1.58 420000.0 -129000.0 -1.61 -2.2567 -0.9999 3187854 PK04_103149 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H12 compound treatment 427200.0 -69600.0 -0.76 497600.0 -51500.0 -0.64 -0.9944 -0.9965 3070553 PK04_103150 CN1CCC(=CC1c2cccs2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H13 compound treatment 445600.0 -51200.0 -0.56 474800.0 -74300.0 -0.93 -1.0536 -0.9707 3187855 PK04_103151 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H14 compound treatment 408400.0 -88400.0 -0.97 421600.0 -128000.0 -1.59 -1.8121 -0.9714 3187856 PK04_103152 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H15 compound treatment 488400.0 -8400.0 -0.09 571200.0 22100.0 0.28 0.1303 0.4475 3070554 PK04_103153 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H16 compound treatment 438800.0 -58000.0 -0.64 516400.0 -32700.0 -0.41 -0.7384 -0.9774 3187857 PK04_103154 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H17 compound treatment 114800.0 -382000.0 -4.18 140400.0 -409000.0 -5.11 -6.572 -0.995 3187858 PK04_103155 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H18 compound treatment 384800.0 -112000.0 -1.23 412400.0 -137000.0 -1.71 -2.0762 -0.9867 3070555 PK04_103156 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H19 mock treatment 474400.0 -22400.0 -0.25 524000.0 -25100.0 -0.31 -0.3955 -0.9925 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H20 mock treatment 466000.0 -30800.0 -0.34 541600.0 -7520.0 -0.09 -0.3049 -0.871 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H21 compound treatment 420400.0 -76400.0 -0.84 431200.0 -118000.0 -1.47 -1.6343 -0.9639 3187859 PK04_103157 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H22 compound treatment 477600.0 -19200.0 -0.21 498400.0 -50700.0 -0.63 -0.5972 -0.8937 3070556 PK04_103158 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H23 compound treatment 522000.0 25200.0 0.28 585200.0 36100.0 0.45 0.5142 0.9721 3187860 PK04_103159 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 H24 compound treatment 552400.0 55600.0 0.61 612000.0 62900.0 0.79 0.9866 0.992 3070597 PK04_103160 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I01 compound treatment 615200.0 118000.0 1.3 668000.0 119000.0 1.49 1.968 0.9977 3187861 PK04_103161 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I02 compound treatment 549600.0 52800.0 0.58 528800.0 -20300.0 -0.25 0.2291 0.3628 3187862 PK04_103162 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I03 compound treatment 508000.0 11200.0 0.12 549200.0 83.9 0.0 0.0875 0.7131 3070598 PK04_103163 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I04 compound treatment 464800.0 -32000.0 -0.35 489600.0 -59500.0 -0.74 -0.7741 -0.9409 3187863 PK04_103164 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I05 mock treatment 466400.0 -30400.0 -0.33 517200.0 -31900.0 -0.4 -0.5176 -0.9959 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I06 mock treatment 483200.0 -13600.0 -0.15 505600.0 -43500.0 -0.54 -0.4901 -0.8687 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I07 compound treatment 430800.0 -66000.0 -0.72 448000.0 -101000.0 -1.26 -1.4052 -0.9648 3070599 PK04_103165 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I08 compound treatment 474400.0 -22400.0 -0.25 501600.0 -47500.0 -0.59 -0.5936 -0.9234 3187864 PK04_103166 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I09 compound treatment 404800.0 -92000.0 -1.01 485200.0 -63900.0 -0.8 -1.2775 -0.9934 3187865 PK04_103167 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I10 compound treatment 410800.0 -86000.0 -0.94 494400.0 -54700.0 -0.68 -1.1497 -0.9877 3070600 PK04_103168 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I11 compound treatment 451600.0 -45200.0 -0.49 444400.0 -105000.0 -1.31 -1.276 -0.9114 3187866 PK04_103169 COCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I12 compound treatment 399200.0 -97600.0 -1.07 436400.0 -113000.0 -1.41 -1.7524 -0.9907 3187978 PK04_103170 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I13 compound treatment 430000.0 -66800.0 -0.73 514000.0 -35100.0 -0.44 -0.8277 -0.9702 3070601 PK04_103171 CCCCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I14 compound treatment 362400.0 -134000.0 -1.47 383600.0 -166000.0 -2.07 -2.5043 -0.986 3187979 PK04_103172 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I15 compound treatment 456000.0 -40800.0 -0.45 492000.0 -57100.0 -0.71 -0.821 -0.9745 3070602 PK04_103173 CC(C)C(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I16 compound treatment 299200.0 -198000.0 -2.16 330800.0 -218000.0 -2.73 -3.4605 -0.9934 3187980 PK04_103174 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I17 compound treatment 434800.0 -62000.0 -0.68 484000.0 -65100.0 -0.81 -1.0559 -0.9959 3070603 PK04_103175 COCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I18 compound treatment 472000.0 -24800.0 -0.27 521200.0 -27900.0 -0.35 -0.4389 -0.9923 3187981 PK04_103176 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I19 compound treatment 403600.0 -93200.0 -1.02 415600.0 -134000.0 -1.67 -1.9023 -0.9721 3070604 PK04_103177 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I20 compound treatment 478400.0 -18400.0 -0.2 492800.0 -56300.0 -0.7 -0.6405 -0.8743 3187982 PK04_103178 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I21 mock treatment 506000.0 9200.0 0.1 537600.0 -11500.0 -0.14 -0.0306 -0.1742 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I22 mock treatment 521600.0 24800.0 0.27 519600.0 -29500.0 -0.37 -0.069 -0.1506 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I23 compound treatment 319600.0 -177000.0 -1.94 327200.0 -222000.0 -2.78 -3.3344 -0.9847 3187983 PK04_103179 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 I24 compound treatment 588800.0 92000.0 1.01 629200.0 80100.0 1.0 1.4205 1.0 3070605 PK04_103180 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J01 compound treatment 179200.0 -318000.0 -3.48 264400.0 -285000.0 -3.56 -4.9768 -0.9999 3187984 PK04_103181 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J02 compound treatment 414000.0 -82800.0 -0.91 539600.0 -9520.0 -0.12 -0.7252 -0.7931 3187985 PK04_103182 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J03 compound treatment 212000.0 -285000.0 -3.12 301200.0 -248000.0 -3.1 -4.3974 -1.0 3070606 PK04_103183 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J04 compound treatment 434000.0 -62800.0 -0.69 530000.0 -19100.0 -0.24 -0.6553 -0.9001 3187986 PK04_103184 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J05 mock treatment 481600.0 -15200.0 -0.17 522400.0 -26700.0 -0.33 -0.3539 -0.9482 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J06 mock treatment 483200.0 -13600.0 -0.15 550400.0 1280.0 0.02 -0.0939 -0.6272 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J07 compound treatment 355200.0 -142000.0 -1.55 430000.0 -119000.0 -1.49 -2.1497 -0.9998 3187987 PK04_103185 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J08 compound treatment 438000.0 -58800.0 -0.64 496400.0 -52700.0 -0.66 -0.9214 -0.9999 3070607 PK04_103186 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J09 compound treatment 436800.0 -60000.0 -0.66 471600.0 -77500.0 -0.97 -1.15 -0.982 3187988 PK04_103187 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J10 compound treatment 425600.0 -71200.0 -0.78 441200.0 -108000.0 -1.35 -1.5056 -0.966 3070608 PK04_103188 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J11 compound treatment 435600.0 -61200.0 -0.67 484400.0 -64700.0 -0.81 -1.0461 -0.9956 3187989 PK04_103189 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J12 compound treatment 452800.0 -44000.0 -0.48 479600.0 -69500.0 -0.87 -0.9554 -0.9612 3070609 PK04_103190 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J13 compound treatment 203600.0 -293000.0 -3.21 217600.0 -332000.0 -4.15 -5.2018 -0.992 3187990 PK04_103191 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J14 compound treatment 430800.0 -66000.0 -0.72 510800.0 -38300.0 -0.48 -0.8498 -0.9801 3187991 PK04_103192 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J15 compound treatment 238800.0 -258000.0 -2.82 270800.0 -278000.0 -3.48 -4.4588 -0.9946 3070610 PK04_103193 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J16 compound treatment 430800.0 -66000.0 -0.72 507600.0 -41500.0 -0.52 -0.8781 -0.9868 3187992 PK04_103194 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J17 compound treatment 74800.0 -422000.0 -4.62 90400.0 -459000.0 -5.74 -7.3239 -0.9942 3070654 PK04_103195 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J18 compound treatment 497600.0 800.0 0.01 502000.0 -47100.0 -0.59 -0.4105 -0.6965 3187993 PK04_103196 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J19 compound treatment 274800.0 -222000.0 -2.43 334000.0 -215000.0 -2.69 -3.6212 -0.9987 3070655 PK04_103197 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J20 compound treatment 416800.0 -80000.0 -0.88 421600.0 -128000.0 -1.59 -1.7471 -0.9602 3187994 PK04_103198 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J21 mock treatment 511600.0 14800.0 0.16 558400.0 9280.0 0.12 0.1967 0.9866 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J22 mock treatment 528000.0 31200.0 0.34 559200.0 10100.0 0.13 0.3307 0.9082 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J23 compound treatment 76400.0 -420000.0 -4.6 88000.0 -461000.0 -5.77 -7.3327 -0.9938 3187995 PK04_103199 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 J24 compound treatment 542000.0 45200.0 0.49 604000.0 54900.0 0.69 0.8353 0.9871 3070656 PK04_103200 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K01 compound treatment 598400.0 102000.0 1.11 653600.0 104000.0 1.31 1.7106 0.9968 3187996 PK04_103201 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K02 compound treatment 405200.0 -91600.0 -1.0 424000.0 -125000.0 -1.56 -1.8156 -0.9769 3187997 PK04_103202 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K03 compound treatment 476000.0 -20800.0 -0.23 475600.0 -73500.0 -0.92 -0.8112 -0.8564 3070657 PK04_103203 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K04 compound treatment 365600.0 -131000.0 -1.44 383600.0 -166000.0 -2.07 -2.4795 -0.9841 3187998 PK04_103204 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K05 compound treatment 425200.0 -71600.0 -0.78 461600.0 -87500.0 -1.09 -1.3283 -0.9866 3070658 PK04_103205 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K06 compound treatment 493600.0 -3200.0 -0.04 528400.0 -20700.0 -0.26 -0.208 -0.7955 3187999 PK04_103206 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K07 mock treatment 440400.0 -56400.0 -0.62 494000.0 -55100.0 -0.69 -0.9241 -0.9985 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K08 mock treatment 468400.0 -28400.0 -0.31 496400.0 -52700.0 -0.66 -0.6861 -0.9412 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K09 compound treatment 469600.0 -27200.0 -0.3 474800.0 -74300.0 -0.93 -0.8678 -0.8892 3188000 PK04_103207 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K10 compound treatment 401200.0 -95600.0 -1.05 438800.0 -110000.0 -1.38 -1.7157 -0.9907 3070659 PK04_103208 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K11 compound treatment 348400.0 -148000.0 -1.62 378000.0 -171000.0 -2.14 -2.6622 -0.9908 3188108 PK04_103209 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K12 compound treatment 342000.0 -155000.0 -1.69 369600.0 -180000.0 -2.25 -2.786 -0.9904 3188109 PK04_103210 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K13 compound treatment 408000.0 -88800.0 -0.97 445600.0 -104000.0 -1.29 -1.603 -0.99 3070660 PK04_103211 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K14 compound treatment 448000.0 -48800.0 -0.53 479600.0 -69500.0 -0.87 -0.9926 -0.9727 3188110 PK04_103212 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K15 mock treatment 487600.0 -9200.0 -0.1 491600.0 -57500.0 -0.72 -0.5799 -0.7983 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K16 mock treatment 499600.0 2800.0 0.03 490800.0 -58300.0 -0.73 -0.494 -0.6768 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K17 compound treatment 415600.0 -81200.0 -0.89 456000.0 -93100.0 -1.16 -1.4521 -0.9911 3070661 PK04_103213 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K18 compound treatment 400800.0 -96000.0 -1.05 426000.0 -123000.0 -1.54 -1.832 -0.9827 3188111 PK04_103214 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K19 compound treatment 414000.0 -82800.0 -0.91 441600.0 -108000.0 -1.34 -1.5919 -0.9816 3188112 PK04_103215 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K20 compound treatment 424800.0 -72000.0 -0.79 458000.0 -91100.0 -1.14 -1.3632 -0.9838 3070662 PK04_103216 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K21 compound treatment 376800.0 -120000.0 -1.31 351600.0 -198000.0 -2.47 -2.6758 -0.9563 3188113 PK04_103217 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K22 compound treatment 541600.0 44800.0 0.49 528000.0 -21100.0 -0.26 0.1601 0.2874 3188114 PK04_103218 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K23 mock treatment 580000.0 83200.0 0.91 602400.0 53300.0 0.67 1.1154 0.9882 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 K24 mock treatment 643600.0 147000.0 1.61 653200.0 104000.0 1.3 2.057 0.9945 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L01 compound treatment 287200.0 -210000.0 -2.29 380400.0 -169000.0 -2.11 -3.1148 -0.9991 3070663 PK04_103219 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L02 compound treatment 395200.0 -102000.0 -1.11 515200.0 -33900.0 -0.42 -1.0866 -0.9126 3188115 PK04_103220 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L03 compound treatment 349200.0 -148000.0 -1.62 437600.0 -112000.0 -1.39 -2.129 -0.9973 3070664 PK04_103221 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L04 compound treatment 372800.0 -124000.0 -1.36 466000.0 -83100.0 -1.04 -1.6951 -0.9913 3188116 PK04_103222 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L05 compound treatment 124800.0 -372000.0 -4.07 199200.0 -350000.0 -4.38 -5.9746 -0.9994 3070665 PK04_103223 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L06 compound treatment 323200.0 -174000.0 -1.9 376400.0 -173000.0 -2.16 -2.8715 -0.998 3188117 PK04_103224 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L07 mock treatment 479200.0 -17600.0 -0.19 592000.0 42900.0 0.54 0.243 0.4263 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L08 mock treatment 480400.0 -16400.0 -0.18 545200.0 -3920.0 -0.05 -0.1616 -0.8683 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L09 compound treatment 306800.0 -190000.0 -2.08 339600.0 -210000.0 -2.62 -3.3239 -0.9935 3188118 PK04_103225 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L10 compound treatment 402800.0 -94000.0 -1.03 428800.0 -120000.0 -1.5 -1.7918 -0.9828 3188119 PK04_103226 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L11 compound treatment 216800.0 -280000.0 -3.07 196000.0 -353000.0 -4.42 -5.2906 -0.9841 3070666 PK04_103227 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L12 compound treatment 302800.0 -194000.0 -2.12 287600.0 -262000.0 -3.27 -3.8147 -0.9782 3188120 PK04_103228 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L13 compound treatment 539200.0 42400.0 0.46 550000.0 884.0 0.01 0.3361 0.7237 3188121 PK04_103229 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L14 compound treatment 398400.0 -98400.0 -1.08 424800.0 -124000.0 -1.55 -1.8612 -0.984 3188122 PK04_103230 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L15 mock treatment 472800.0 -24000.0 -0.26 597200.0 48100.0 0.6 0.2394 0.3648 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L16 mock treatment 495600.0 -1200.0 -0.01 553200.0 4080.0 0.05 0.0268 0.5086 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L17 compound treatment 428400.0 -68400.0 -0.75 519600.0 -29500.0 -0.37 -0.7906 -0.9469 3070709 PK04_103231 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L18 compound treatment 453200.0 -43600.0 -0.48 530800.0 -18300.0 -0.23 -0.4995 -0.9434 3188123 PK04_103232 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L19 compound treatment 411200.0 -85600.0 -0.94 556000.0 6880.0 0.09 -0.6019 -0.6395 3070710 PK04_103233 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L20 compound treatment 202800.0 -294000.0 -3.22 358400.0 -191000.0 -2.39 -3.9628 -0.9891 3188124 PK04_103234 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L21 compound treatment 625600.0 129000.0 1.41 566000.0 16900.0 0.21 1.1465 0.804 3070711 PK04_103235 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L22 compound treatment 627200.0 130000.0 1.43 536400.0 -12700.0 -0.16 0.8972 0.6245 3188125 PK04_103236 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L23 mock treatment 654800.0 158000.0 1.73 600000.0 50900.0 0.64 1.6733 0.9077 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 L24 mock treatment 681600.0 185000.0 2.02 669600.0 120000.0 1.51 2.4963 0.9895 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M01 compound treatment 309600.0 -187000.0 -2.05 323200.0 -226000.0 -2.83 -3.4472 -0.9876 3070712 PK04_103237 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M02 compound treatment 508800.0 12000.0 0.13 522800.0 -26300.0 -0.33 -0.1398 -0.3945 3188126 PK04_103238 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M03 compound treatment 484000.0 -12800.0 -0.14 498000.0 -51100.0 -0.64 -0.5511 -0.8421 3070713 PK04_103239 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M04 compound treatment 424400.0 -72400.0 -0.79 452800.0 -96300.0 -1.2 -1.4123 -0.9794 3188127 PK04_103240 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M05 compound treatment 501200.0 4400.0 0.05 505600.0 -43500.0 -0.54 -0.3508 -0.642 3188128 PK04_103241 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M06 compound treatment 565200.0 68400.0 0.75 572800.0 23700.0 0.3 0.739 0.9176 3070714 PK04_103242 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M07 compound treatment 480400.0 -16400.0 -0.18 501600.0 -47500.0 -0.59 -0.5472 -0.8814 3188237 PK04_103243 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M08 compound treatment 484000.0 -12800.0 -0.14 524800.0 -24300.0 -0.3 -0.3141 -0.9382 3070715 PK04_103244 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M09 mock treatment 491200.0 -5600.0 -0.06 526400.0 -22700.0 -0.28 -0.2442 -0.8404 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M10 mock treatment 474000.0 -22800.0 -0.25 495200.0 -53900.0 -0.67 -0.6533 -0.9086 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M11 compound treatment 446400.0 -50400.0 -0.55 461200.0 -87900.0 -1.1 -1.1677 -0.9492 3188238 PK04_103245 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M12 compound treatment 299200.0 -198000.0 -2.16 322400.0 -227000.0 -2.84 -3.5348 -0.9911 3188239 PK04_103246 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M13 mock treatment 490000.0 -6800.0 -0.07 512400.0 -36700.0 -0.46 -0.3773 -0.8112 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M14 mock treatment 506800.0 10000.0 0.11 511600.0 -37500.0 -0.47 -0.2543 -0.5279 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M15 compound treatment 413200.0 -83600.0 -0.92 426400.0 -123000.0 -1.53 -1.7325 -0.9695 3070716 PK04_103247 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M16 compound treatment 444800.0 -52000.0 -0.57 455200.0 -93900.0 -1.17 -1.2331 -0.9447 3188240 PK04_103248 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M17 compound treatment 119600.0 -377000.0 -4.13 140000.0 -409000.0 -5.12 -6.5384 -0.9944 3070717 PK04_103249 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M18 compound treatment 388000.0 -109000.0 -1.19 378400.0 -171000.0 -2.14 -2.3521 -0.962 3188241 PK04_103250 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M19 compound treatment 479600.0 -17200.0 -0.19 529600.0 -19500.0 -0.24 -0.3058 -0.9918 3188242 PK04_103251 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M20 compound treatment 332400.0 -164000.0 -1.8 344400.0 -205000.0 -2.56 -3.0832 -0.9851 3070718 PK04_103252 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M21 compound treatment 492800.0 -4000.0 -0.04 496400.0 -52700.0 -0.66 -0.4972 -0.7524 3188243 PK04_103253 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M22 compound treatment 372400.0 -124000.0 -1.36 383200.0 -166000.0 -2.08 -2.4304 -0.9792 3188244 PK04_103254 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M23 compound treatment 566400.0 69600.0 0.76 601600.0 52500.0 0.66 1.003 0.9972 3188245 PK04_103255 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 M24 compound treatment 646800.0 150000.0 1.64 622800.0 73700.0 0.92 1.813 0.9627 3070768 PK04_103256 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N01 compound treatment 498400.0 1600.0 0.02 695200.0 146000.0 1.83 1.3043 0.7139 3188246 PK04_103257 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N02 compound treatment 426000.0 -70800.0 -0.78 561600.0 12500.0 0.16 -0.4378 -0.5536 3188247 PK04_103258 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N03 compound treatment 478400.0 -18400.0 -0.2 555200.0 6080.0 0.08 -0.0887 -0.4117 3070772 PK04_103259 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N04 compound treatment 416800.0 -80000.0 -0.88 499600.0 -49500.0 -0.62 -1.0573 -0.9856 3188248 PK04_103260 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N05 compound treatment 500400.0 3600.0 0.04 560400.0 11300.0 0.14 0.1277 0.8713 3188249 PK04_103261 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N06 compound treatment 390800.0 -106000.0 -1.16 366800.0 -182000.0 -2.28 -2.433 -0.9509 3188250 PK04_103262 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N07 compound treatment 561200.0 64400.0 0.71 596400.0 47300.0 0.59 0.9168 0.9962 3070060 PK04_103263 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N08 compound treatment 427200.0 -69600.0 -0.76 484400.0 -64700.0 -0.81 -1.1112 -0.9995 3188251 PK04_103264 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N09 mock treatment 519200.0 22400.0 0.25 551600.0 2480.0 0.03 0.1954 0.7904 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N10 mock treatment 446800.0 -50000.0 -0.55 518400.0 -30700.0 -0.38 -0.6588 -0.985 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N11 compound treatment 474800.0 -22000.0 -0.24 578400.0 29300.0 0.37 0.0886 0.2022 3070061 PK04_103265 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N12 compound treatment 465200.0 -31600.0 -0.35 554000.0 4880.0 0.06 -0.2015 -0.5734 3188252 PK04_103266 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N13 mock treatment 517600.0 20800.0 0.23 587200.0 38100.0 0.48 0.4978 0.943 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N14 mock treatment 552800.0 56000.0 0.61 612000.0 62900.0 0.79 0.9897 0.9924 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N15 compound treatment 452000.0 -44800.0 -0.49 516800.0 -32300.0 -0.4 -0.6326 -0.9954 3070062 PK04_103267 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N16 compound treatment 549600.0 52800.0 0.58 654800.0 106000.0 1.32 1.3434 0.9312 3188253 PK04_103268 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N17 compound treatment 400400.0 -96400.0 -1.06 435600.0 -114000.0 -1.42 -1.7502 -0.9894 3070063 PK04_103269 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N18 compound treatment 518800.0 22000.0 0.24 537600.0 -11500.0 -0.14 0.0685 0.244 3188254 PK04_103270 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N19 compound treatment 536400.0 39600.0 0.43 575600.0 26500.0 0.33 0.5408 0.9912 3070064 PK04_103271 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N20 compound treatment 456400.0 -40400.0 -0.44 470000.0 -79100.0 -0.99 -1.0124 -0.9341 3188255 PK04_103272 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N21 compound treatment 542000.0 45200.0 0.49 590000.0 40900.0 0.51 0.7115 0.9999 3070065 PK04_103273 CCCCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N22 compound treatment 592000.0 95200.0 1.04 560000.0 10900.0 0.14 0.8333 0.7927 3188256 PK04_103274 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N23 compound treatment 620800.0 124000.0 1.36 646800.0 97700.0 1.22 1.8239 0.9986 3070066 PK04_103275 CC(C)C(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 N24 compound treatment 704000.0 207000.0 2.27 712800.0 164000.0 2.05 3.0517 0.9987 3188257 PK04_103276 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O01 compound treatment 721600.0 225000.0 2.46 768000.0 219000.0 2.74 3.6762 0.9986 3188258 PK04_103277 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O02 compound treatment 694400.0 198000.0 2.16 696800.0 148000.0 1.85 2.8359 0.9969 3070067 PK04_103278 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O03 compound treatment 597600.0 101000.0 1.1 622000.0 72900.0 0.91 1.425 0.9955 3188259 PK04_103279 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O04 compound treatment 642000.0 145000.0 1.59 657200.0 108000.0 1.35 2.08 0.9967 3188369 PK04_103280 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O05 compound treatment 584400.0 87600.0 0.96 613600.0 64500.0 0.81 1.2485 0.9963 3070068 PK04_103281 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O06 compound treatment 569200.0 72400.0 0.79 601600.0 52500.0 0.66 1.0247 0.9956 3188370 PK04_103282 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O07 compound treatment 528800.0 32000.0 0.35 515600.0 -33500.0 -0.42 -0.0486 -0.089 3070069 PK04_103283 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O08 compound treatment 414000.0 -82800.0 -0.91 445200.0 -104000.0 -1.3 -1.56 -0.9845 3188371 PK04_103284 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O09 compound treatment 504000.0 7200.0 0.08 543600.0 -5520.0 -0.07 0.007 0.0665 3188372 PK04_103285 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O10 compound treatment 442000.0 -54800.0 -0.6 500000.0 -49100.0 -0.61 -0.8586 -0.9999 3070070 PK04_103286 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O11 mock treatment 567600.0 70800.0 0.78 603200.0 54100.0 0.68 1.0264 0.9977 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O12 mock treatment 524000.0 27200.0 0.3 604800.0 55700.0 0.7 0.703 0.9282 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O13 compound treatment 504000.0 7200.0 0.08 590400.0 41300.0 0.52 0.4208 0.8057 3188373 PK04_103287 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O14 compound treatment 343600.0 -153000.0 -1.68 348000.0 -201000.0 -2.52 -2.9647 -0.9806 3188374 PK04_103288 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O15 compound treatment 381600.0 -115000.0 -1.26 444800.0 -104000.0 -1.3 -1.8144 -0.9999 3070071 PK04_103289 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O16 compound treatment 363600.0 -133000.0 -1.46 393200.0 -156000.0 -1.95 -2.4101 -0.9898 3188375 PK04_103290 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O17 compound treatment 402400.0 -94400.0 -1.03 430400.0 -119000.0 -1.48 -1.7807 -0.9843 3070072 PK04_103291 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O18 compound treatment 141200.0 -356000.0 -3.89 147200.0 -402000.0 -5.03 -6.3075 -0.992 3188376 PK04_103292 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O19 compound treatment 564800.0 68000.0 0.74 590400.0 41300.0 0.52 0.8916 0.984 3188377 PK04_103293 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O20 compound treatment 347600.0 -149000.0 -1.63 391200.0 -158000.0 -1.97 -2.5517 -0.9956 3070073 PK04_103294 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O21 compound treatment 486000.0 -10800.0 -0.12 498400.0 -50700.0 -0.63 -0.5321 -0.8247 3188378 PK04_103295 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O22 compound treatment 385600.0 -111000.0 -1.22 394400.0 -155000.0 -1.93 -2.2292 -0.9751 3188379 PK04_103296 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O23 compound treatment 658000.0 161000.0 1.77 656800.0 108000.0 1.35 2.2004 0.9911 3070074 PK04_103297 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 O24 compound treatment 734000.0 237000.0 2.6 782400.0 233000.0 2.92 3.8995 0.9983 3188380 PK04_103298 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P01 compound treatment 568400.0 71600.0 0.78 736400.0 187000.0 2.34 2.2106 0.895 3070075 PK04_103299 COCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P02 compound treatment 552800.0 56000.0 0.61 729600.0 180000.0 2.26 2.0297 0.8677 3188381 PK04_103300 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P03 compound treatment 467200.0 -29600.0 -0.32 554000.0 4880.0 0.06 -0.186 -0.5639 3188382 PK04_103301 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P04 compound treatment 530800.0 34000.0 0.37 576400.0 27300.0 0.34 0.5045 0.9991 3070118 PK04_103302 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P05 compound treatment 552000.0 55200.0 0.6 611600.0 62500.0 0.78 0.9799 0.9919 3188383 PK04_103303 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P06 compound treatment 664400.0 168000.0 1.84 660400.0 111000.0 1.39 2.2817 0.9907 3070119 PK04_103304 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P07 compound treatment 653200.0 156000.0 1.71 688800.0 140000.0 1.75 2.4462 1.0 3188384 PK04_103305 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P08 compound treatment 577600.0 80800.0 0.88 663200.0 114000.0 1.43 1.6345 0.9736 3188385 PK04_103306 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P09 compound treatment 436800.0 -60000.0 -0.66 514000.0 -35100.0 -0.44 -0.7751 -0.9808 3070120 PK04_103307 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P10 compound treatment 509200.0 12400.0 0.14 550000.0 884.0 0.01 0.1038 0.7622 3188386 PK04_103308 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P11 mock treatment 626000.0 129000.0 1.41 651600.0 102000.0 1.28 1.9066 0.9988 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P12 mock treatment 655200.0 158000.0 1.73 653200.0 104000.0 1.3 2.1468 0.99 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P13 compound treatment 519600.0 22800.0 0.25 630000.0 80900.0 1.01 0.8918 0.8559 3070121 PK04_103309 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P14 compound treatment 683600.0 187000.0 2.05 705200.0 156000.0 1.95 2.8266 0.9997 3188387 PK04_103310 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P15 compound treatment 613200.0 116000.0 1.27 684000.0 135000.0 1.69 2.094 0.9904 3188388 PK04_103311 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P16 compound treatment 625600.0 129000.0 1.41 693600.0 144000.0 1.81 2.2749 0.9925 3070122 PK04_103312 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P17 compound treatment 449200.0 -47600.0 -0.52 541600.0 -7520.0 -0.09 -0.435 -0.8214 3188389 PK04_103313 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P18 compound treatment 498800.0 2000.0 0.02 612400.0 63300.0 0.79 0.5751 0.7264 3188390 PK04_103314 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P19 compound treatment 314400.0 -182000.0 -2.0 313200.0 -236000.0 -2.95 -3.4985 -0.9819 3070123 PK04_103315 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P20 compound treatment 572800.0 76000.0 0.83 642400.0 93300.0 1.17 1.4134 0.9863 3188503 PK04_103316 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P21 compound treatment 588800.0 92000.0 1.01 669600.0 120000.0 1.51 1.7778 0.9808 3188504 PK04_103317 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P22 compound treatment 677200.0 180000.0 1.98 751200.0 202000.0 2.53 3.1838 0.9926 3070124 PK04_103318 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P23 compound treatment 651600.0 155000.0 1.69 643200.0 94100.0 1.18 2.0305 0.9841 3188505 PK04_103319 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.2103 P24 compound treatment 476000.0 -20800.0 -0.23 482800.0 -66300.0 -0.83 -0.7475 -0.8691 3188506 PK04_103320 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A01 mock treatment 593200.0 177000.0 1.94 536400.0 149000.0 1.87 2.6887 0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A02 mock treatment 505200.0 88800.0 0.97 504800.0 118000.0 1.47 1.7279 0.9797 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A03 mock treatment 502400.0 86000.0 0.94 455600.0 68500.0 0.86 1.2711 0.9989 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A04 mock treatment 473200.0 56800.0 0.62 429600.0 42500.0 0.53 0.8151 0.9969 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A05 mock treatment 474400.0 58000.0 0.63 420400.0 33300.0 0.42 0.7431 0.979 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A06 mock treatment 439600.0 23200.0 0.25 428400.0 41300.0 0.52 0.5444 0.9465 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A07 mock treatment 467600.0 51200.0 0.56 440800.0 53700.0 0.67 0.8708 0.996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A08 mock treatment 482400.0 66000.0 0.72 420800.0 33700.0 0.42 0.8085 0.967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A09 mock treatment 469600.0 53200.0 0.58 426400.0 39300.0 0.49 0.7589 0.9964 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A10 mock treatment 490800.0 74400.0 0.81 439600.0 52500.0 0.66 1.0398 0.9943 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A11 mock treatment 473200.0 56800.0 0.62 428400.0 41300.0 0.52 0.8045 0.9957 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A12 mock treatment 500000.0 83600.0 0.92 439600.0 52500.0 0.66 1.111 0.9867 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A13 mock treatment 477600.0 61200.0 0.67 428000.0 40900.0 0.51 0.835 0.9911 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A14 mock treatment 462000.0 45600.0 0.5 464400.0 77300.0 0.97 1.0362 0.9527 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A15 mock treatment 487200.0 70800.0 0.77 429200.0 42100.0 0.53 0.92 0.9822 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A16 mock treatment 482000.0 65600.0 0.72 471600.0 84500.0 1.06 1.2547 0.9823 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A17 mock treatment 509600.0 93200.0 1.02 446400.0 59300.0 0.74 1.2455 0.9877 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A18 mock treatment 521200.0 105000.0 1.15 451600.0 64500.0 0.81 1.3813 0.9851 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A19 mock treatment 419200.0 2770.0 0.03 426400.0 39300.0 0.49 0.3687 0.7493 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A20 mock treatment 456800.0 40400.0 0.44 445200.0 58100.0 0.73 0.8261 0.9716 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A21 mock treatment 486400.0 70000.0 0.77 452400.0 65300.0 0.82 1.1189 0.9995 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A22 mock treatment 492000.0 75600.0 0.83 475200.0 88100.0 1.1 1.3639 0.9901 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A23 mock treatment 574400.0 158000.0 1.73 510800.0 124000.0 1.55 2.3167 0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base A24 mock treatment 655200.0 239000.0 2.61 567200.0 180000.0 2.25 3.4411 0.9972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B01 mock treatment 708400.0 292000.0 3.2 473200.0 86100.0 1.08 3.0217 0.8958 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B02 mock treatment 522400.0 106000.0 1.16 424000.0 36900.0 0.46 1.1465 0.9183 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B03 mock treatment 524800.0 108000.0 1.19 409200.0 22100.0 0.28 1.0342 0.8489 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B04 mock treatment 475200.0 58800.0 0.64 396800.0 9670.0 0.12 0.5405 0.8256 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B05 mock treatment 417200.0 766.0 0.01 416800.0 29700.0 0.37 0.2684 0.7229 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B06 mock treatment 442400.0 26000.0 0.28 424000.0 36900.0 0.46 0.5271 0.973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B07 mock treatment 476000.0 59600.0 0.65 398400.0 11300.0 0.14 0.5609 0.8406 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B08 mock treatment 498400.0 82000.0 0.9 395200.0 8070.0 0.1 0.706 0.7817 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B09 mock treatment 467200.0 50800.0 0.56 419600.0 32500.0 0.41 0.6802 0.9881 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B10 mock treatment 490400.0 74000.0 0.81 410000.0 22900.0 0.29 0.775 0.9022 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B11 mock treatment 439600.0 23200.0 0.25 416400.0 29300.0 0.37 0.4382 0.9839 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B12 mock treatment 448800.0 32400.0 0.35 411600.0 24500.0 0.31 0.467 0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B13 mock treatment 430400.0 14000.0 0.15 410000.0 22900.0 0.29 0.3104 0.957 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B14 mock treatment 443200.0 26800.0 0.29 443200.0 56100.0 0.7 0.7031 0.9251 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B15 mock treatment 442400.0 26000.0 0.28 397200.0 10100.0 0.13 0.2901 0.933 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B16 mock treatment 419600.0 3170.0 0.03 419200.0 32100.0 0.4 0.3082 0.7654 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B17 mock treatment 442400.0 26000.0 0.28 419200.0 32100.0 0.4 0.4847 0.9858 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B18 mock treatment 437200.0 20800.0 0.23 392000.0 4870.0 0.06 0.2039 0.8661 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B19 mock treatment 427200.0 10800.0 0.12 409600.0 22500.0 0.28 0.2821 0.9256 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B20 mock treatment 439600.0 23200.0 0.25 440400.0 53300.0 0.67 0.6505 0.9124 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B21 mock treatment 428000.0 11600.0 0.13 396800.0 9670.0 0.12 0.1751 0.9997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B22 mock treatment 457600.0 41200.0 0.45 424800.0 37700.0 0.47 0.6519 0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B23 mock treatment 489600.0 73200.0 0.8 413600.0 26500.0 0.33 0.8006 0.9236 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base B24 mock treatment 512800.0 96400.0 1.06 495600.0 108000.0 1.36 1.7054 0.9923 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C01 mock treatment 496400.0 80000.0 0.88 477600.0 90500.0 1.13 1.4192 0.992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C02 mock treatment 449200.0 32800.0 0.36 406400.0 19300.0 0.24 0.4241 0.9813 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C03 mock treatment 411200.0 -5230.0 -0.06 405600.0 18500.0 0.23 0.1229 0.5161 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C04 mock treatment 427200.0 10800.0 0.12 353600.0 -33500.0 -0.42 -0.2131 -0.4893 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C05 mock treatment 404800.0 -11600.0 -0.13 378000.0 -9130.0 -0.11 -0.1708 -0.9985 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C06 mock treatment 404000.0 -12400.0 -0.14 346000.0 -41100.0 -0.51 -0.46 -0.8645 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C07 mock treatment 414000.0 -2430.0 -0.03 381600.0 -5530.0 -0.07 -0.0677 -0.9141 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C08 mock treatment 386000.0 -30400.0 -0.33 365600.0 -21500.0 -0.27 -0.426 -0.9944 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C09 mock treatment 412400.0 -4030.0 -0.04 376400.0 -10700.0 -0.13 -0.1261 -0.8928 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C10 mock treatment 392400.0 -24000.0 -0.26 376000.0 -11100.0 -0.14 -0.2845 -0.9556 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C11 mock treatment 364800.0 -51600.0 -0.57 366000.0 -21100.0 -0.26 -0.5866 -0.94 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C12 mock treatment 401200.0 -15200.0 -0.17 356400.0 -30700.0 -0.38 -0.3897 -0.9302 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C13 mock treatment 407200.0 -9230.0 -0.1 346400.0 -40700.0 -0.51 -0.4316 -0.8312 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C14 mock treatment 408000.0 -8430.0 -0.09 355200.0 -31900.0 -0.4 -0.3476 -0.8483 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C15 mock treatment 412000.0 -4430.0 -0.05 381600.0 -5530.0 -0.07 -0.0832 -0.9851 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C16 mock treatment 382800.0 -33600.0 -0.37 396400.0 9270.0 0.12 -0.1784 -0.462 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C17 mock treatment 398400.0 -18000.0 -0.2 361600.0 -25500.0 -0.32 -0.3654 -0.9733 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C18 mock treatment 436800.0 20400.0 0.22 380800.0 -6330.0 -0.08 0.1017 0.43 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C19 mock treatment 412000.0 -4430.0 -0.05 398400.0 11300.0 0.14 0.0654 0.4384 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C20 mock treatment 395200.0 -21200.0 -0.23 365600.0 -21500.0 -0.27 -0.3548 -0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C21 mock treatment 408400.0 -8030.0 -0.09 375600.0 -11500.0 -0.14 -0.1641 -0.9719 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C22 mock treatment 428800.0 12400.0 0.14 384400.0 -2730.0 -0.03 0.0716 0.5131 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C23 mock treatment 469600.0 53200.0 0.58 448000.0 60900.0 0.76 0.95 0.9912 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base C24 mock treatment 508400.0 92000.0 1.01 473600.0 86500.0 1.08 1.4768 0.9994 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D01 mock treatment 584800.0 168000.0 1.84 436400.0 49300.0 0.62 1.7393 0.8948 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D02 mock treatment 502400.0 86000.0 0.94 410000.0 22900.0 0.29 0.8679 0.8822 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D03 mock treatment 463200.0 46800.0 0.51 372400.0 -14700.0 -0.18 0.2319 0.4261 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D04 mock treatment 453600.0 37200.0 0.41 370400.0 -16700.0 -0.21 0.1398 0.3056 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D05 mock treatment 432800.0 16400.0 0.18 386800.0 -326.0 0.0 0.1238 0.6908 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D06 mock treatment 431200.0 14800.0 0.16 370400.0 -16700.0 -0.21 -0.0336 -0.127 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D07 mock treatment 452800.0 36400.0 0.4 371600.0 -15500.0 -0.19 0.1443 0.3256 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D08 mock treatment 418000.0 1570.0 0.02 382000.0 -5130.0 -0.06 -0.0332 -0.5003 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D09 mock treatment 395600.0 -20800.0 -0.23 381200.0 -5930.0 -0.07 -0.2137 -0.891 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D10 mock treatment 392400.0 -24000.0 -0.26 363600.0 -23500.0 -0.29 -0.3941 -0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D11 mock treatment 376000.0 -40400.0 -0.44 352000.0 -35100.0 -0.44 -0.6237 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D12 mock treatment 387600.0 -28800.0 -0.32 370400.0 -16700.0 -0.21 -0.3712 -0.98 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D13 mock treatment 396400.0 -20000.0 -0.22 389200.0 2070.0 0.03 -0.1368 -0.6192 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D14 mock treatment 397200.0 -19200.0 -0.21 391600.0 4470.0 0.06 -0.1093 -0.5018 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D15 mock treatment 380800.0 -35600.0 -0.39 373600.0 -13500.0 -0.17 -0.3955 -0.93 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D16 mock treatment 389600.0 -26800.0 -0.29 354800.0 -32300.0 -0.4 -0.4936 -0.9877 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D17 mock treatment 393200.0 -23200.0 -0.25 348400.0 -38700.0 -0.48 -0.5224 -0.9548 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D18 mock treatment 404000.0 -12400.0 -0.14 372400.0 -14700.0 -0.18 -0.2265 -0.9889 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D19 mock treatment 393200.0 -23200.0 -0.25 369600.0 -17500.0 -0.22 -0.3349 -0.9972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D20 mock treatment 404800.0 -11600.0 -0.13 358400.0 -28700.0 -0.36 -0.3441 -0.9028 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D21 mock treatment 377200.0 -39200.0 -0.43 383600.0 -3530.0 -0.04 -0.3349 -0.7756 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D22 mock treatment 398800.0 -17600.0 -0.19 408000.0 20900.0 0.26 0.0481 0.148 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D23 mock treatment 420000.0 3570.0 0.04 419200.0 32100.0 0.4 0.3113 0.7723 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base D24 mock treatment 467200.0 50800.0 0.56 454400.0 67300.0 0.84 0.988 0.9798 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E01 mock treatment 497600.0 81200.0 0.89 453200.0 66100.0 0.83 1.2127 0.9993 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E02 mock treatment 435600.0 19200.0 0.21 423200.0 36100.0 0.45 0.4674 0.9394 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E03 mock treatment 392000.0 -24400.0 -0.27 377200.0 -9930.0 -0.12 -0.277 -0.939 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E04 mock treatment 386800.0 -29600.0 -0.32 348800.0 -38300.0 -0.48 -0.5684 -0.9819 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E05 mock treatment 374800.0 -41600.0 -0.46 362400.0 -24700.0 -0.31 -0.541 -0.9821 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E06 mock treatment 372000.0 -44400.0 -0.49 357200.0 -29900.0 -0.37 -0.6087 -0.9916 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E07 mock treatment 369600.0 -46800.0 -0.51 374400.0 -12700.0 -0.16 -0.4751 -0.8849 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E08 mock treatment 374800.0 -41600.0 -0.46 340000.0 -47100.0 -0.59 -0.7391 -0.9919 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E09 mock treatment 377200.0 -39200.0 -0.43 358800.0 -28300.0 -0.35 -0.5543 -0.9954 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E10 mock treatment 372400.0 -44000.0 -0.48 344000.0 -43100.0 -0.54 -0.7223 -0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E11 mock treatment 371600.0 -44800.0 -0.49 370000.0 -17100.0 -0.21 -0.4986 -0.9309 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E12 mock treatment 365200.0 -51200.0 -0.56 333600.0 -53500.0 -0.67 -0.87 -0.9961 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E13 mock treatment 395600.0 -20800.0 -0.23 357600.0 -29500.0 -0.37 -0.4224 -0.9732 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E14 mock treatment 380800.0 -35600.0 -0.39 353200.0 -33900.0 -0.42 -0.5759 -0.9991 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E15 mock treatment 392400.0 -24000.0 -0.26 349200.0 -37900.0 -0.47 -0.5215 -0.9614 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E16 mock treatment 396000.0 -20400.0 -0.22 358400.0 -28700.0 -0.36 -0.4122 -0.974 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E17 mock treatment 357600.0 -58800.0 -0.64 352000.0 -35100.0 -0.44 -0.7661 -0.9826 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E18 mock treatment 390800.0 -25600.0 -0.28 353200.0 -33900.0 -0.42 -0.4985 -0.9799 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E19 mock treatment 387200.0 -29200.0 -0.32 340400.0 -46700.0 -0.58 -0.6396 -0.9599 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E20 mock treatment 368400.0 -48000.0 -0.53 364000.0 -23100.0 -0.29 -0.5764 -0.9603 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E21 mock treatment 380000.0 -36400.0 -0.4 390400.0 3270.0 0.04 -0.2531 -0.6312 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E22 mock treatment 412400.0 -4030.0 -0.04 357600.0 -29500.0 -0.37 -0.2923 -0.7861 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E23 mock treatment 454400.0 38000.0 0.42 408000.0 20900.0 0.26 0.4785 0.9749 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base E24 mock treatment 485200.0 68800.0 0.75 458800.0 71700.0 0.9 1.1663 0.9962 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F01 mock treatment 568000.0 152000.0 1.66 477200.0 90100.0 1.13 1.97 0.9822 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F02 mock treatment 495200.0 78800.0 0.86 378400.0 -8730.0 -0.11 0.5327 0.6127 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F03 mock treatment 437600.0 21200.0 0.23 362400.0 -24700.0 -0.31 -0.0548 -0.1418 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F04 mock treatment 430400.0 14000.0 0.15 374000.0 -13100.0 -0.16 -0.0079 -0.0354 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F05 mock treatment 414400.0 -2030.0 -0.02 386400.0 -726.0 -0.01 -0.0222 -0.9218 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F06 mock treatment 402000.0 -14400.0 -0.16 384000.0 -3130.0 -0.04 -0.1394 -0.8562 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F07 mock treatment 412800.0 -3630.0 -0.04 385200.0 -1930.0 -0.02 -0.0452 -0.9711 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F08 mock treatment 404000.0 -12400.0 -0.14 368800.0 -18300.0 -0.23 -0.2583 -0.9691 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F09 mock treatment 410800.0 -5630.0 -0.06 366000.0 -21100.0 -0.26 -0.2304 -0.8494 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F10 mock treatment 382400.0 -34000.0 -0.37 373200.0 -13900.0 -0.17 -0.3867 -0.94 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F11 mock treatment 385600.0 -30800.0 -0.34 365600.0 -21500.0 -0.27 -0.4291 -0.9937 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F12 mock treatment 384800.0 -31600.0 -0.35 363600.0 -23500.0 -0.29 -0.453 -0.9967 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F13 mock treatment 385600.0 -30800.0 -0.34 380800.0 -6330.0 -0.08 -0.2947 -0.8498 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F14 mock treatment 395200.0 -21200.0 -0.23 362800.0 -24300.0 -0.3 -0.3795 -0.9912 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F15 mock treatment 417200.0 766.0 0.01 358400.0 -28700.0 -0.36 -0.2481 -0.6904 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F16 mock treatment 400000.0 -16400.0 -0.18 369200.0 -17900.0 -0.22 -0.2858 -0.9941 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F17 mock treatment 391200.0 -25200.0 -0.28 375600.0 -11500.0 -0.14 -0.2973 -0.954 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F18 mock treatment 384800.0 -31600.0 -0.35 369600.0 -17500.0 -0.22 -0.3999 -0.9756 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F19 mock treatment 350400.0 -66000.0 -0.72 357200.0 -29900.0 -0.37 -0.7759 -0.953 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F20 mock treatment 410000.0 -6430.0 -0.07 364000.0 -23100.0 -0.29 -0.2543 -0.8544 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F21 mock treatment 414000.0 -2430.0 -0.03 377200.0 -9930.0 -0.12 -0.1066 -0.8398 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F22 mock treatment 418000.0 1570.0 0.02 370400.0 -16700.0 -0.21 -0.1358 -0.647 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F23 mock treatment 438400.0 22000.0 0.24 423600.0 36500.0 0.46 0.4926 0.9553 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base F24 mock treatment 434400.0 18000.0 0.2 432000.0 44900.0 0.56 0.5359 0.9012 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G01 mock treatment 480000.0 63600.0 0.7 448800.0 61700.0 0.77 1.0376 0.9987 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G02 mock treatment 390400.0 -26000.0 -0.29 419200.0 32100.0 0.4 0.0821 0.1668 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G03 mock treatment 382000.0 -34400.0 -0.38 372800.0 -14300.0 -0.18 -0.3933 -0.9422 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G04 mock treatment 358000.0 -58400.0 -0.64 348400.0 -38700.0 -0.48 -0.7949 -0.9906 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G05 mock treatment 364000.0 -52400.0 -0.57 370400.0 -16700.0 -0.21 -0.5539 -0.9065 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G06 mock treatment 347200.0 -69200.0 -0.76 342400.0 -44700.0 -0.56 -0.9316 -0.9888 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G07 mock treatment 372800.0 -43600.0 -0.48 335200.0 -51900.0 -0.65 -0.797 -0.9886 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G08 mock treatment 352400.0 -64000.0 -0.7 325600.0 -61500.0 -0.77 -1.0399 -0.9989 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G09 mock treatment 381600.0 -34800.0 -0.38 339600.0 -47500.0 -0.59 -0.69 -0.977 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G10 mock treatment 354400.0 -62000.0 -0.68 331600.0 -55500.0 -0.69 -0.9713 -0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G11 mock treatment 342800.0 -73600.0 -0.81 361600.0 -25500.0 -0.32 -0.7958 -0.9178 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G12 mock treatment 342000.0 -74400.0 -0.82 329200.0 -57900.0 -0.72 -1.0886 -0.9983 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G13 mock treatment 359600.0 -56800.0 -0.62 352800.0 -34300.0 -0.43 -0.7436 -0.9836 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G14 mock treatment 355200.0 -61200.0 -0.67 351200.0 -35900.0 -0.45 -0.7918 -0.981 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G15 mock treatment 355200.0 -61200.0 -0.67 333200.0 -53900.0 -0.67 -0.951 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G16 mock treatment 358800.0 -57600.0 -0.63 304800.0 -82300.0 -1.03 -1.1743 -0.9724 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G17 mock treatment 357200.0 -59200.0 -0.65 341600.0 -45500.0 -0.57 -0.8612 -0.9979 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G18 mock treatment 359200.0 -57200.0 -0.63 332800.0 -54300.0 -0.68 -0.9235 -0.9992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G19 mock treatment 382000.0 -34400.0 -0.38 362000.0 -25100.0 -0.31 -0.4888 -0.9959 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G20 mock treatment 383200.0 -33200.0 -0.36 340000.0 -47100.0 -0.59 -0.6741 -0.9731 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G21 mock treatment 385200.0 -31200.0 -0.34 357200.0 -29900.0 -0.37 -0.5065 -0.999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G22 mock treatment 399200.0 -17200.0 -0.19 369600.0 -17500.0 -0.22 -0.2884 -0.9972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G23 mock treatment 424000.0 7570.0 0.08 386000.0 -1130.0 -0.01 0.0486 0.5786 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base G24 mock treatment 498400.0 82000.0 0.9 448400.0 61300.0 0.77 1.1765 0.9969 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H01 mock treatment 590000.0 174000.0 1.9 443600.0 56500.0 0.71 1.8432 0.9091 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H02 mock treatment 467600.0 51200.0 0.56 390800.0 3670.0 0.05 0.4286 0.7625 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H03 mock treatment 416800.0 366.0 0.0 367200.0 -19900.0 -0.25 -0.1734 -0.6956 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H04 mock treatment 395600.0 -20800.0 -0.23 390000.0 2870.0 0.04 -0.1359 -0.5884 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H05 mock treatment 395200.0 -21200.0 -0.23 367600.0 -19500.0 -0.24 -0.3371 -0.9997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H06 mock treatment 374000.0 -42400.0 -0.46 384400.0 -2730.0 -0.03 -0.3526 -0.757 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H07 mock treatment 390800.0 -25600.0 -0.28 372400.0 -14700.0 -0.18 -0.3287 -0.9791 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H08 mock treatment 391200.0 -25200.0 -0.28 364000.0 -23100.0 -0.29 -0.3999 -0.9997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H09 mock treatment 356000.0 -60400.0 -0.66 350800.0 -36300.0 -0.45 -0.7891 -0.9832 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H10 mock treatment 367600.0 -48800.0 -0.53 357600.0 -29500.0 -0.37 -0.6392 -0.9837 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H11 mock treatment 367600.0 -48800.0 -0.53 376400.0 -10700.0 -0.13 -0.4729 -0.8579 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H12 mock treatment 387600.0 -28800.0 -0.32 374800.0 -12300.0 -0.15 -0.3322 -0.9457 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H13 mock treatment 375600.0 -40800.0 -0.45 385600.0 -1530.0 -0.02 -0.3296 -0.7366 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H14 mock treatment 363200.0 -53200.0 -0.58 379200.0 -7930.0 -0.1 -0.4822 -0.8156 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H15 mock treatment 406400.0 -10000.0 -0.11 337600.0 -49500.0 -0.62 -0.5157 -0.8197 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H16 mock treatment 356800.0 -59600.0 -0.65 350800.0 -36300.0 -0.45 -0.7829 -0.9843 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H17 mock treatment 372800.0 -43600.0 -0.48 349600.0 -37500.0 -0.47 -0.6697 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H18 mock treatment 377200.0 -39200.0 -0.43 324000.0 -63100.0 -0.79 -0.862 -0.9591 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H19 mock treatment 372400.0 -44000.0 -0.48 337200.0 -49900.0 -0.62 -0.7824 -0.9918 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H20 mock treatment 382400.0 -34000.0 -0.37 349600.0 -37500.0 -0.47 -0.5954 -0.9935 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H21 mock treatment 380000.0 -36400.0 -0.4 372400.0 -14700.0 -0.18 -0.4123 -0.9384 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H22 mock treatment 361600.0 -54800.0 -0.6 372800.0 -14300.0 -0.18 -0.5512 -0.8798 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H23 mock treatment 423600.0 7170.0 0.08 384800.0 -2330.0 -0.03 0.0349 0.4172 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base H24 mock treatment 484800.0 68400.0 0.75 446800.0 59700.0 0.75 1.057 1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I01 mock treatment 486400.0 70000.0 0.77 413200.0 26100.0 0.33 0.7723 0.9276 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I02 mock treatment 428800.0 12400.0 0.14 383200.0 -3930.0 -0.05 0.061 0.4237 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I03 mock treatment 427600.0 11200.0 0.12 368400.0 -18700.0 -0.23 -0.0791 -0.2996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I04 mock treatment 396400.0 -20000.0 -0.22 354400.0 -32700.0 -0.41 -0.4445 -0.9573 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I05 mock treatment 356800.0 -59600.0 -0.65 364800.0 -22300.0 -0.28 -0.6591 -0.9282 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I06 mock treatment 357600.0 -58800.0 -0.64 346800.0 -40300.0 -0.5 -0.8121 -0.9927 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I07 mock treatment 375600.0 -40800.0 -0.45 373200.0 -13900.0 -0.17 -0.4393 -0.9155 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I08 mock treatment 376800.0 -39600.0 -0.43 342800.0 -44300.0 -0.55 -0.6988 -0.9927 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I09 mock treatment 378000.0 -38400.0 -0.42 332800.0 -54300.0 -0.68 -0.778 -0.9735 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I10 mock treatment 338800.0 -77600.0 -0.85 357600.0 -29500.0 -0.37 -0.8622 -0.9303 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I11 mock treatment 349200.0 -67200.0 -0.74 336400.0 -50700.0 -0.63 -0.9691 -0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I12 mock treatment 363600.0 -52800.0 -0.58 339600.0 -47500.0 -0.59 -0.8293 -0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I13 mock treatment 347600.0 -68800.0 -0.75 342800.0 -44300.0 -0.55 -0.9249 -0.9886 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I14 mock treatment 350400.0 -66000.0 -0.72 344800.0 -42300.0 -0.53 -0.8856 -0.9883 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I15 mock treatment 351200.0 -65200.0 -0.71 322000.0 -65100.0 -0.81 -1.081 -0.9979 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I16 mock treatment 364800.0 -51600.0 -0.57 323600.0 -63500.0 -0.79 -0.9615 -0.9861 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I17 mock treatment 328800.0 -87600.0 -0.96 350800.0 -36300.0 -0.45 -0.9997 -0.9417 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I18 mock treatment 361200.0 -55200.0 -0.6 352400.0 -34700.0 -0.43 -0.7347 -0.9868 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I19 mock treatment 360000.0 -56400.0 -0.62 338800.0 -48300.0 -0.6 -0.8643 -0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I20 mock treatment 385600.0 -30800.0 -0.34 334800.0 -52300.0 -0.65 -0.7015 -0.9526 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I21 mock treatment 364400.0 -52000.0 -0.57 372400.0 -14700.0 -0.18 -0.5331 -0.8903 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I22 mock treatment 396800.0 -19600.0 -0.21 370400.0 -16700.0 -0.21 -0.2999 -0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I23 mock treatment 402800.0 -13600.0 -0.15 414000.0 26900.0 0.34 0.1321 0.3592 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base I24 mock treatment 488800.0 72400.0 0.79 416800.0 29700.0 0.37 0.8227 0.9403 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J01 mock treatment 506800.0 90400.0 0.99 452000.0 64900.0 0.81 1.2734 0.9951 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J02 mock treatment 442000.0 25600.0 0.28 359200.0 -27900.0 -0.35 -0.049 -0.1095 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J03 mock treatment 426000.0 9570.0 0.1 400400.0 13300.0 0.17 0.1915 0.9753 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J04 mock treatment 402400.0 -14000.0 -0.15 370400.0 -16700.0 -0.21 -0.2566 -0.9885 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J05 mock treatment 380800.0 -35600.0 -0.39 364000.0 -23100.0 -0.29 -0.4804 -0.9891 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J06 mock treatment 377600.0 -38800.0 -0.43 377200.0 -9930.0 -0.12 -0.3884 -0.8769 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J07 mock treatment 394000.0 -22400.0 -0.25 346400.0 -40700.0 -0.51 -0.5338 -0.9441 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J08 mock treatment 384000.0 -32400.0 -0.36 353200.0 -33900.0 -0.42 -0.5511 -0.9961 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J09 mock treatment 362800.0 -53600.0 -0.59 350400.0 -36700.0 -0.46 -0.74 -0.9926 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J10 mock treatment 360800.0 -55600.0 -0.61 366000.0 -21100.0 -0.26 -0.6176 -0.9301 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J11 mock treatment 374800.0 -41600.0 -0.46 376800.0 -10300.0 -0.13 -0.4137 -0.8731 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J12 mock treatment 390000.0 -26400.0 -0.29 355200.0 -31900.0 -0.4 -0.487 -0.9875 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J13 mock treatment 388800.0 -27600.0 -0.3 365600.0 -21500.0 -0.27 -0.4043 -0.9983 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J14 mock treatment 403200.0 -13200.0 -0.14 362000.0 -25100.0 -0.31 -0.3247 -0.9382 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J15 mock treatment 380800.0 -35600.0 -0.39 348000.0 -39100.0 -0.49 -0.6219 -0.9937 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J16 mock treatment 378000.0 -38400.0 -0.42 354000.0 -33100.0 -0.41 -0.5905 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J17 mock treatment 369600.0 -46800.0 -0.51 342400.0 -44700.0 -0.56 -0.7581 -0.9991 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J18 mock treatment 362400.0 -54000.0 -0.59 352400.0 -34700.0 -0.43 -0.7254 -0.9884 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J19 mock treatment 357600.0 -58800.0 -0.64 350800.0 -36300.0 -0.45 -0.7768 -0.9854 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J20 mock treatment 344800.0 -71600.0 -0.78 358400.0 -28700.0 -0.36 -0.8086 -0.9373 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J21 mock treatment 332800.0 -83600.0 -0.92 375200.0 -11900.0 -0.15 -0.753 -0.8116 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J22 mock treatment 394000.0 -22400.0 -0.25 364800.0 -22300.0 -0.28 -0.3711 -0.998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J23 mock treatment 457600.0 41200.0 0.45 406400.0 19300.0 0.24 0.4892 0.957 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base J24 mock treatment 529600.0 113000.0 1.24 436800.0 49700.0 0.62 1.3155 0.949 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K01 mock treatment 469200.0 52800.0 0.58 442400.0 55300.0 0.69 0.8973 0.996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K02 mock treatment 421200.0 4770.0 0.05 401200.0 14100.0 0.18 0.1614 0.8789 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K03 mock treatment 407200.0 -9230.0 -0.1 380000.0 -7130.0 -0.09 -0.1345 -0.998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K04 mock treatment 395200.0 -21200.0 -0.23 352000.0 -35100.0 -0.44 -0.475 -0.9557 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K05 mock treatment 364400.0 -52000.0 -0.57 348000.0 -39100.0 -0.49 -0.7489 -0.9971 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K06 mock treatment 376400.0 -40000.0 -0.44 346400.0 -40700.0 -0.51 -0.6701 -0.9972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K07 mock treatment 354000.0 -62400.0 -0.68 330000.0 -57100.0 -0.71 -0.9886 -0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K08 mock treatment 360000.0 -56400.0 -0.62 341600.0 -45500.0 -0.57 -0.8395 -0.9992 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K09 mock treatment 390400.0 -26000.0 -0.29 342000.0 -45100.0 -0.56 -0.6006 -0.95 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K10 mock treatment 379200.0 -37200.0 -0.41 322000.0 -65100.0 -0.81 -0.8642 -0.9488 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K11 mock treatment 383200.0 -33200.0 -0.36 364400.0 -22700.0 -0.28 -0.4583 -0.9925 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K12 mock treatment 374000.0 -42400.0 -0.46 346400.0 -40700.0 -0.51 -0.6887 -0.9989 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K13 mock treatment 349600.0 -66800.0 -0.73 355600.0 -31500.0 -0.39 -0.7962 -0.9579 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K14 mock treatment 368800.0 -47600.0 -0.52 346000.0 -41100.0 -0.51 -0.7325 -1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K15 mock treatment 372800.0 -43600.0 -0.48 333600.0 -53500.0 -0.67 -0.8112 -0.9863 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K16 mock treatment 368800.0 -47600.0 -0.52 337600.0 -49500.0 -0.62 -0.8068 -0.9963 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K17 mock treatment 376400.0 -40000.0 -0.44 340400.0 -46700.0 -0.58 -0.7232 -0.99 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K18 mock treatment 390400.0 -26000.0 -0.29 354000.0 -33100.0 -0.41 -0.4945 -0.9834 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K19 mock treatment 385600.0 -30800.0 -0.34 334000.0 -53100.0 -0.66 -0.7085 -0.9507 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K20 mock treatment 396800.0 -19600.0 -0.21 361600.0 -25500.0 -0.32 -0.3777 -0.9815 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K21 mock treatment 398400.0 -18000.0 -0.2 350000.0 -37100.0 -0.46 -0.4679 -0.9274 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K22 mock treatment 398000.0 -18400.0 -0.2 366000.0 -21100.0 -0.26 -0.3295 -0.9912 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K23 mock treatment 406800.0 -9630.0 -0.11 417200.0 30100.0 0.38 0.1914 0.4899 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base K24 mock treatment 506800.0 90400.0 0.99 416000.0 28900.0 0.36 0.955 0.9067 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L01 mock treatment 556000.0 140000.0 1.53 464400.0 77300.0 0.97 1.7639 0.9756 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L02 mock treatment 496800.0 80400.0 0.88 403200.0 16100.0 0.2 0.7644 0.8468 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L03 mock treatment 468400.0 52000.0 0.57 402000.0 14900.0 0.19 0.5339 0.8918 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L04 mock treatment 420800.0 4370.0 0.05 387600.0 474.0 0.01 0.038 0.7887 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L05 mock treatment 403600.0 -12800.0 -0.14 363200.0 -23900.0 -0.3 -0.3109 -0.9406 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L06 mock treatment 358400.0 -58000.0 -0.64 390400.0 3270.0 0.04 -0.4204 -0.6602 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L07 mock treatment 353600.0 -62800.0 -0.69 368000.0 -19100.0 -0.24 -0.6556 -0.9001 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L08 mock treatment 373200.0 -43200.0 -0.47 361600.0 -25500.0 -0.32 -0.5605 -0.9816 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L09 mock treatment 390800.0 -25600.0 -0.28 341200.0 -45900.0 -0.57 -0.6046 -0.9458 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L10 mock treatment 418400.0 1970.0 0.02 374000.0 -13100.0 -0.16 -0.1009 -0.6091 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L11 mock treatment 388800.0 -27600.0 -0.3 365200.0 -21900.0 -0.27 -0.4078 -0.9988 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L12 mock treatment 407200.0 -9230.0 -0.1 377200.0 -9930.0 -0.12 -0.1593 -0.9948 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L13 mock treatment 418800.0 2370.0 0.03 383200.0 -3930.0 -0.05 -0.0164 -0.2954 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L14 mock treatment 377200.0 -39200.0 -0.43 379600.0 -7530.0 -0.09 -0.3703 -0.8421 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L15 mock treatment 370400.0 -46000.0 -0.5 368400.0 -18700.0 -0.23 -0.522 -0.9392 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L16 mock treatment 408400.0 -8030.0 -0.09 377200.0 -9930.0 -0.12 -0.15 -0.9858 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L17 mock treatment 419200.0 2770.0 0.03 371200.0 -15900.0 -0.2 -0.1194 -0.5928 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L18 mock treatment 405200.0 -11200.0 -0.12 374000.0 -13100.0 -0.16 -0.2031 -0.9899 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L19 mock treatment 385200.0 -31200.0 -0.34 354000.0 -33100.0 -0.41 -0.5348 -0.9955 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L20 mock treatment 406800.0 -9630.0 -0.11 362800.0 -24300.0 -0.3 -0.2897 -0.8997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L21 mock treatment 425600.0 9170.0 0.1 365200.0 -21900.0 -0.27 -0.1229 -0.421 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L22 mock treatment 414800.0 -1630.0 -0.02 371600.0 -15500.0 -0.19 -0.1499 -0.769 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L23 mock treatment 435600.0 19200.0 0.21 380000.0 -7130.0 -0.09 0.0854 0.3745 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base L24 mock treatment 476800.0 60400.0 0.66 437200.0 50100.0 0.63 0.9102 0.9996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M01 mock treatment 472400.0 56000.0 0.61 460800.0 73700.0 0.92 1.0848 0.9804 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M02 mock treatment 458800.0 42400.0 0.46 390000.0 2870.0 0.04 0.3534 0.7596 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M03 mock treatment 410800.0 -5630.0 -0.06 391200.0 4070.0 0.05 -0.0076 -0.0949 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M04 mock treatment 410800.0 -5630.0 -0.06 360000.0 -27100.0 -0.34 -0.2835 -0.8222 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M05 mock treatment 394800.0 -21600.0 -0.24 337600.0 -49500.0 -0.62 -0.6055 -0.913 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M06 mock treatment 384000.0 -32400.0 -0.36 350400.0 -36700.0 -0.46 -0.5759 -0.9919 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M07 mock treatment 389200.0 -27200.0 -0.3 368000.0 -19100.0 -0.24 -0.38 -0.994 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M08 mock treatment 331200.0 -85200.0 -0.93 346000.0 -41100.0 -0.51 -1.0236 -0.9606 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M09 mock treatment 377200.0 -39200.0 -0.43 347200.0 -39900.0 -0.5 -0.6568 -0.9972 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M10 mock treatment 362800.0 -53600.0 -0.59 339200.0 -47900.0 -0.6 -0.8391 -0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M11 mock treatment 368000.0 -48400.0 -0.53 350800.0 -36300.0 -0.45 -0.6962 -0.997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M12 mock treatment 366800.0 -49600.0 -0.54 358400.0 -28700.0 -0.36 -0.6383 -0.9798 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M13 mock treatment 370800.0 -45600.0 -0.5 340800.0 -46300.0 -0.58 -0.763 -0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M14 mock treatment 365600.0 -50800.0 -0.56 356400.0 -30700.0 -0.38 -0.6653 -0.9836 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M15 mock treatment 368400.0 -48000.0 -0.53 361200.0 -25900.0 -0.32 -0.6012 -0.973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M16 mock treatment 401200.0 -15200.0 -0.17 357200.0 -29900.0 -0.37 -0.3826 -0.9337 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M17 mock treatment 404000.0 -12400.0 -0.14 362000.0 -25100.0 -0.31 -0.3185 -0.9299 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M18 mock treatment 363600.0 -52800.0 -0.58 351200.0 -35900.0 -0.45 -0.7268 -0.9922 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M19 mock treatment 371200.0 -45200.0 -0.5 362000.0 -25100.0 -0.31 -0.5724 -0.9759 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M20 mock treatment 403600.0 -12800.0 -0.14 367200.0 -19900.0 -0.25 -0.2756 -0.9632 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M21 mock treatment 392000.0 -24400.0 -0.27 370800.0 -16300.0 -0.2 -0.3336 -0.9911 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M22 mock treatment 404400.0 -12000.0 -0.13 408000.0 20900.0 0.26 0.0914 0.3127 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M23 mock treatment 449200.0 32800.0 0.36 416000.0 28900.0 0.36 0.509 1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base M24 mock treatment 524800.0 108000.0 1.19 473200.0 86100.0 1.08 1.6002 0.9988 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N01 mock treatment 575600.0 159000.0 1.74 474800.0 87700.0 1.1 2.0077 0.9751 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N02 mock treatment 524800.0 108000.0 1.19 406800.0 19700.0 0.25 1.013 0.836 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N03 mock treatment 474800.0 58400.0 0.64 396800.0 9670.0 0.12 0.5374 0.8263 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N04 mock treatment 430400.0 14000.0 0.15 394800.0 7670.0 0.1 0.176 0.9748 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N05 mock treatment 406800.0 -9630.0 -0.11 380800.0 -6330.0 -0.08 -0.1305 -0.99 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N06 mock treatment 440000.0 23600.0 0.26 384800.0 -2330.0 -0.03 0.1619 0.6234 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N07 mock treatment 390400.0 -26000.0 -0.29 375600.0 -11500.0 -0.14 -0.3035 -0.9501 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N08 mock treatment 392800.0 -23600.0 -0.26 342400.0 -44700.0 -0.56 -0.5785 -0.9387 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N09 mock treatment 408400.0 -8030.0 -0.09 352800.0 -34300.0 -0.43 -0.3658 -0.8347 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N10 mock treatment 400000.0 -16400.0 -0.18 366000.0 -21100.0 -0.26 -0.3141 -0.9825 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N11 mock treatment 399200.0 -17200.0 -0.19 406000.0 18900.0 0.24 0.0335 0.1108 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N12 mock treatment 408400.0 -8030.0 -0.09 398000.0 10900.0 0.14 0.034 0.2097 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N13 mock treatment 387200.0 -29200.0 -0.32 408400.0 21300.0 0.27 -0.0382 -0.0918 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N14 mock treatment 383600.0 -32800.0 -0.36 391600.0 4470.0 0.06 -0.2146 -0.59 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N15 mock treatment 414400.0 -2030.0 -0.02 379200.0 -7930.0 -0.1 -0.0858 -0.8449 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N16 mock treatment 444000.0 27600.0 0.3 360800.0 -26300.0 -0.33 -0.0194 -0.0434 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N17 mock treatment 438800.0 22400.0 0.24 375200.0 -11900.0 -0.15 0.0677 0.2361 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N18 mock treatment 414000.0 -2430.0 -0.03 393200.0 6070.0 0.08 0.0349 0.4332 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N19 mock treatment 411200.0 -5230.0 -0.06 375200.0 -11900.0 -0.15 -0.146 -0.9137 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N20 mock treatment 409200.0 -7230.0 -0.08 405200.0 18100.0 0.23 0.1038 0.4335 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N21 mock treatment 427200.0 10800.0 0.12 405200.0 18100.0 0.23 0.2432 0.9539 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N22 mock treatment 459600.0 43200.0 0.47 408400.0 21300.0 0.27 0.5223 0.963 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N23 mock treatment 471600.0 55200.0 0.6 452800.0 65700.0 0.82 1.0079 0.9886 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base N24 mock treatment 523600.0 107000.0 1.17 477200.0 90100.0 1.13 1.6263 0.9998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O01 mock treatment 541600.0 125000.0 1.37 527200.0 140000.0 1.75 2.2078 0.9926 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O02 mock treatment 490800.0 74400.0 0.81 455600.0 68500.0 0.86 1.1813 0.9997 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O03 mock treatment 420800.0 4370.0 0.05 415200.0 28100.0 0.35 0.2821 0.796 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O04 mock treatment 455600.0 39200.0 0.43 414000.0 26900.0 0.34 0.5409 0.9927 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O05 mock treatment 414400.0 -2030.0 -0.02 384400.0 -2730.0 -0.03 -0.0399 -0.9787 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O06 mock treatment 447600.0 31200.0 0.34 399600.0 12500.0 0.16 0.3516 0.9371 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O07 mock treatment 436000.0 19600.0 0.21 383200.0 -3930.0 -0.05 0.1168 0.5313 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O08 mock treatment 426800.0 10400.0 0.11 384800.0 -2330.0 -0.03 0.0597 0.5094 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O09 mock treatment 427600.0 11200.0 0.12 408800.0 21700.0 0.27 0.2781 0.9353 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O10 mock treatment 426400.0 9970.0 0.11 394800.0 7670.0 0.1 0.145 0.998 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O11 mock treatment 423200.0 6770.0 0.07 399600.0 12500.0 0.16 0.1627 0.9421 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O12 mock treatment 456400.0 40000.0 0.44 380000.0 -7130.0 -0.09 0.2464 0.5518 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O13 mock treatment 431200.0 14800.0 0.16 380400.0 -6730.0 -0.08 0.0548 0.3009 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O14 mock treatment 424000.0 7570.0 0.08 397200.0 10100.0 0.13 0.1477 0.9793 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O15 mock treatment 409600.0 -6830.0 -0.07 398800.0 11700.0 0.15 0.0503 0.3068 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O16 mock treatment 465200.0 48800.0 0.53 424000.0 36900.0 0.46 0.7037 0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O17 mock treatment 440800.0 24400.0 0.27 378400.0 -8730.0 -0.11 0.1115 0.3868 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O18 mock treatment 436000.0 19600.0 0.21 408400.0 21300.0 0.27 0.3396 0.9942 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O19 mock treatment 444400.0 28000.0 0.31 395600.0 8470.0 0.11 0.2915 0.8995 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O20 mock treatment 464000.0 47600.0 0.52 416800.0 29700.0 0.37 0.6307 0.9862 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O21 mock treatment 461600.0 45200.0 0.49 413600.0 26500.0 0.33 0.5838 0.981 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O22 mock treatment 473600.0 57200.0 0.63 428000.0 40900.0 0.51 0.8041 0.9949 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O23 mock treatment 478000.0 61600.0 0.67 512800.0 126000.0 1.57 1.588 0.9286 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base O24 mock treatment 564400.0 148000.0 1.62 529600.0 142000.0 1.78 2.4056 0.9989 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P01 mock treatment 731600.0 315000.0 3.45 587200.0 200000.0 2.5 4.2095 0.9875 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P02 mock treatment 583200.0 167000.0 1.83 486800.0 99700.0 1.25 2.1726 0.9827 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P03 mock treatment 545600.0 129000.0 1.41 468400.0 81300.0 1.02 1.7188 0.9869 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P04 mock treatment 502000.0 85600.0 0.94 455200.0 68100.0 0.85 1.2645 0.9989 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P05 mock treatment 529600.0 113000.0 1.24 476000.0 88900.0 1.11 1.6621 0.9985 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P06 mock treatment 517600.0 101000.0 1.11 496800.0 110000.0 1.37 1.7532 0.9944 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P07 mock treatment 460400.0 44000.0 0.48 454400.0 67300.0 0.84 0.9353 0.9649 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P08 mock treatment 496000.0 79600.0 0.87 418000.0 30900.0 0.39 0.8891 0.933 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P09 mock treatment 475200.0 58800.0 0.64 472000.0 84900.0 1.06 1.2056 0.9712 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P10 mock treatment 456800.0 40400.0 0.44 483600.0 96500.0 1.21 1.1657 0.9072 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P11 mock treatment 482800.0 66400.0 0.73 470400.0 83300.0 1.04 1.2503 0.9845 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P12 mock treatment 486800.0 70400.0 0.77 471600.0 84500.0 1.06 1.2918 0.988 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P13 mock treatment 519200.0 103000.0 1.13 470800.0 83700.0 1.05 1.5356 0.9993 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P14 mock treatment 484400.0 68000.0 0.74 458000.0 70900.0 0.89 1.153 0.9962 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P15 mock treatment 508000.0 91600.0 1.0 483200.0 96100.0 1.2 1.5586 0.996 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P16 mock treatment 480400.0 64000.0 0.7 444800.0 57700.0 0.72 1.0053 0.9999 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P17 mock treatment 487200.0 70800.0 0.77 480400.0 93300.0 1.17 1.3728 0.9802 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P18 mock treatment 513600.0 97200.0 1.06 485600.0 98500.0 1.23 1.6231 0.9973 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P19 mock treatment 481200.0 64800.0 0.71 454800.0 67700.0 0.85 1.0999 0.9961 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P20 mock treatment 410000.0 -6430.0 -0.07 492400.0 105000.0 1.32 0.8812 0.6683 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P21 mock treatment 523600.0 107000.0 1.17 470800.0 83700.0 1.05 1.5697 0.9984 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P22 mock treatment 569200.0 153000.0 1.67 507600.0 120000.0 1.51 2.2482 0.9986 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P23 mock treatment 621600.0 205000.0 2.25 570000.0 183000.0 2.29 3.2057 1.0 1014.0012 LuxReporter(1014.0012) SplicosomeInhibition 1014.0012.Base P24 mock treatment 695200.0 279000.0 3.05 578400.0 191000.0 2.39 3.8498 0.9927