ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A01 compound treatment 1946794.0 -1520000.0 -1.28 2726895.0 -651000.0 -0.52 -1.2734 -0.9208 3628332 CBKinase1_018161 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A02 compound treatment 2404036.0 -1060000.0 -0.9 3578962.0 201000.0 0.16 -0.5204 -0.5716 3628333 CBKinase1_018162 Cc1cc(Br)c(NC(=O)CSc2ncn(n2)c3ccccc3)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A03 compound treatment 1748350.0 -1720000.0 -1.45 2632318.0 -746000.0 -0.59 -1.445 -0.9225 3628334 CBKinase1_018163 Cn1c(NCCCO)nc2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A04 compound treatment 2278676.0 -1190000.0 -1.0 3554277.0 176000.0 0.14 -0.6091 -0.602 3628335 CBKinase1_018164 COc1cc2c(cc1NC(=O)CN(C)S(=O)(=O)c3ccc(C)cc3)oc4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A05 compound treatment 1952520.0 -1510000.0 -1.28 3604045.0 226000.0 0.18 -0.7756 -0.6014 3628336 CBKinase1_018165 COc1ccc(NC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A06 compound treatment 2375877.0 -1090000.0 -0.92 2507779.0 -870000.0 -0.69 -1.1409 -0.9903 3628337 CBKinase1_018166 CC(=O)c1cccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3c(C)cc(C)cc3C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A07 compound treatment 2125266.0 -1340000.0 -1.13 2412679.0 -965000.0 -0.77 -1.344 -0.9823 1986342 CBKinase1_018167 CN(C)S(=O)(=O)N(CC(=O)Nc1ccccc1F)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A08 compound treatment 2406048.0 -1060000.0 -0.89 2952179.0 -426000.0 -0.34 -0.8725 -0.9119 3628338 CBKinase1_018168 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)NC4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A09 compound treatment 2408239.0 -1060000.0 -0.89 3024687.0 -353000.0 -0.28 -0.8303 -0.8871 3628339 CBKinase1_018169 COc1cc(C)nc(NC(=O)COc2ccc(Cl)cc2C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A10 compound treatment 2304621.0 -1160000.0 -0.98 2953710.0 -424000.0 -0.34 -0.9321 -0.8991 3628340 CBKinase1_018170 CC(=O)c1cccc(NC(=O)CSc2nccc(C)n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A11 compound treatment 2692028.0 -774000.0 -0.65 2987620.0 -390000.0 -0.31 -0.6819 -0.9424 3628341 CBKinase1_018171 Cc1nn(c(OC(=O)CC2CCCCC2)c1S(=O)(=O)c3ccccc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A12 compound treatment 2578360.0 -888000.0 -0.75 3180850.0 -197000.0 -0.16 -0.6408 -0.8372 3628342 CBKinase1_018172 Cc1c(NC(=O)CSc2nnnn2c3cc(C)ccc3C)c(=O)n(c4ccccc4)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A13 mock treatment 2290244.0 -1180000.0 -0.99 3247651.0 -130000.0 -0.1 -0.775 -0.7769 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A14 mock treatment 2747879.0 -719000.0 -0.61 3186791.0 -191000.0 -0.15 -0.5364 -0.8581 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A15 compound treatment 2541455.0 -925000.0 -0.78 2928816.0 -449000.0 -0.36 -0.8049 -0.9376 3628343 CBKinase1_018173 COc1cccc(NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A16 compound treatment 2713016.0 -754000.0 -0.64 3266759.0 -111000.0 -0.09 -0.5121 -0.798 3628344 CBKinase1_018174 Cc1ccc(cc1Cl)c2nnc(SCC(=O)c3ccccc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A17 compound treatment 2807308.0 -659000.0 -0.56 3219682.0 -158000.0 -0.13 -0.4824 -0.846 3628345 CBKinase1_018175 COc1ccc(OC(C)c2nc(no2)c3cccnc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A18 compound treatment 2752071.0 -714000.0 -0.6 3233574.0 -144000.0 -0.12 -0.5075 -0.8272 3628346 CBKinase1_018176 COc1cc(NC(=O)CS(=O)(=O)Cc2ccccc2)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A19 compound treatment 2737745.0 -729000.0 -0.61 3395171.0 17200.0 0.01 -0.425 -0.6911 3628347 CBKinase1_018177 CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A20 compound treatment 2966306.0 -500000.0 -0.42 3328623.0 -49300.0 -0.04 -0.3261 -0.7697 3628348 CBKinase1_018178 COC(=O)c1cc(NC(=O)CSc2nnc(N)s2)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A21 compound treatment 3261727.0 -205000.0 -0.17 3444219.0 66300.0 0.05 -0.0848 -0.4694 3628349 CBKinase1_018179 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2c(C)cc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A22 compound treatment 3474249.0 7720.0 0.01 3642953.0 265000.0 0.21 0.154 0.7286 3628350 CBKinase1_018180 COc1ccccc1NC(=O)Cn2nc(c3cccc(c3)[N+](=O)[O-])c4ccccc4c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A23 compound treatment 2971863.0 -495000.0 -0.42 3001469.0 -376000.0 -0.3 -0.5072 -0.9869 3628351 CBKinase1_018181 COc1ccccc1NC(=O)C2=C(C)Nc3nnnn3C2c4ccccc4OCc5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 A24 compound treatment 2472629.0 -994000.0 -0.84 2824696.0 -553000.0 -0.44 -0.9046 -0.955 3628352 CBKinase1_018182 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B01 compound treatment 3298394.0 -168000.0 -0.14 3056330.0 -322000.0 -0.26 -0.2815 -0.961 3628353 CBKinase1_018183 Brc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c4ccccc24)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B02 compound treatment 3162322.0 -304000.0 -0.26 3065043.0 -313000.0 -0.25 -0.3578 -0.9999 3628354 CBKinase1_018184 OC(=O)c1cccc(c1)S(=O)(=O)NCC2CCCO2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B03 compound treatment 3435642.0 -30900.0 -0.03 3683522.0 306000.0 0.24 0.1538 0.6279 3628355 CBKinase1_018185 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(Cl)c1)C2CCCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B04 compound treatment 3115664.0 -351000.0 -0.3 3279452.0 -98500.0 -0.08 -0.2648 -0.8648 3628356 CBKinase1_018186 CCn1c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)nnc1c3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B05 compound treatment 3500537.0 34000.0 0.03 3478806.0 101000.0 0.08 0.0771 0.9036 3628357 CBKinase1_018187 Cc1ccc(CCC(=O)Nc2ccc(/C=C/c3ccccc3)cc2)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B06 compound treatment 3434879.0 -31600.0 -0.03 3487571.0 110000.0 0.09 0.0429 0.4697 3628359 CBKinase1_018188 O=C(CSc1nnc(c2cccs2)n1c3ccccc3)N4CCCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B07 compound treatment 3094634.0 -372000.0 -0.31 2814744.0 -563000.0 -0.45 -0.5392 -0.9846 1984364 CBKinase1_018189 Cc1ccc(Nc2nc(CSc3nnnn3c4ccccc4)cc(=O)[nH]2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B08 compound treatment 3452330.0 -14200.0 -0.01 3371300.0 -6640.0 -0.01 -0.0122 -0.9327 3628360 CBKinase1_018190 COc1cccc(OC)c1C(=O)NC(=S)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B09 compound treatment 3506459.0 39900.0 0.03 3063669.0 -314000.0 -0.25 -0.1533 -0.6066 3628361 CBKinase1_018191 CCn1c(SCC(=O)Nc2ccccc2N3CCOCC3)nnc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B10 compound treatment 3442737.0 -23800.0 -0.02 2983728.0 -394000.0 -0.31 -0.2364 -0.7507 3628362 CBKinase1_018192 COC(=O)c1c(NC(=O)COc2ccccc2C(C)C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B11 compound treatment 3738852.0 272000.0 0.23 3403697.0 25800.0 0.02 0.1769 0.7672 3628363 CBKinase1_018193 COc1cc(cc(Br)c1OCC(=O)O)c2nc3ccccc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B12 compound treatment 3642617.0 176000.0 0.15 3515693.0 138000.0 0.11 0.1827 0.9889 3628364 CBKinase1_018194 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2C)c3nn4c(C)nnc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B13 mock treatment 3516516.0 50000.0 0.04 3351965.0 -26000.0 -0.02 0.0152 0.323 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B14 mock treatment 3488880.0 22400.0 0.02 3640812.0 263000.0 0.21 0.1615 0.7676 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B15 compound treatment 3602103.0 136000.0 0.11 3568235.0 190000.0 0.15 0.1881 0.9903 3628365 CBKinase1_018195 Brc1ccc(NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B16 compound treatment 3325384.0 -141000.0 -0.12 3155849.0 -222000.0 -0.18 -0.2094 -0.9814 3628366 CBKinase1_018196 Cc1ccc(NC(=O)Cn2nc(c3cccc(c3)[N+](=O)[O-])c4ccccc4c2=O)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B17 compound treatment 3586274.0 120000.0 0.1 3271226.0 -107000.0 -0.09 0.0113 0.0854 3628367 CBKinase1_018197 O=C(Cn1cc(C(=O)c2cccs2)c3ccccc13)NCC4CCCO4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B18 compound treatment 3483730.0 17200.0 0.01 3283545.0 -94400.0 -0.08 -0.0429 -0.5604 3628368 CBKinase1_018198 CC(C)(C)c1ccc(OCC(=O)Nc2ccccc2C(=O)N)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B19 compound treatment 3762749.0 296000.0 0.25 3571665.0 194000.0 0.15 0.2859 0.9732 3628369 CBKinase1_018199 CCc1cc2c(NCC3CCCO3)ncnc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B20 compound treatment 3826368.0 360000.0 0.3 3758676.0 381000.0 0.3 0.4292 1.0 3628370 CBKinase1_018200 COc1ccccc1Nc2nc(N)nc(CN3CCC(Cc4ccccc4)CC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B21 compound treatment 4107424.0 641000.0 0.54 3756179.0 378000.0 0.3 0.5954 0.962 3628371 CBKinase1_018201 COC(=O)c1ccccc1NC(=O)COc2ccc(cc2Br)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B22 compound treatment 3576171.0 110000.0 0.09 3725258.0 347000.0 0.28 0.2611 0.8947 3628372 CBKinase1_018202 Cc1sc2ncnc(SCC(=O)Nc3ccccc3[N+](=O)[O-])c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B23 compound treatment 3475474.0 8950.0 0.01 3635822.0 258000.0 0.21 0.1507 0.7326 3628373 CBKinase1_018203 CCOC(=O)Cc1c(C)nc2c(c(C)nn2c1C)c3ccccc3OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 B24 compound treatment 2960507.0 -506000.0 -0.43 3264678.0 -113000.0 -0.09 -0.3656 -0.8381 3628374 CBKinase1_018204 Cc1cccc(NC(=O)CSc2nnc(c3cccs3)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C01 compound treatment 1943308.0 -1520000.0 -1.28 4520078.0 1140000.0 0.91 -0.2648 -0.1682 3628375 CBKinase1_018205 NC(=O)CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C02 compound treatment 1870199.0 -1600000.0 -1.35 3141203.0 -237000.0 -0.19 -1.0855 -0.7984 3628376 CBKinase1_018206 O=C(CSc1nc2ccccc2[nH]1)Nc3ccccc3N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C03 compound treatment 1918934.0 -1550000.0 -1.31 3088478.0 -289000.0 -0.23 -1.0862 -0.8194 3628377 CBKinase1_018207 COc1ccccc1CC(=O)Nc2ccc(cc2)c3noc(n3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C04 compound treatment 1941214.0 -1530000.0 -1.29 2656989.0 -721000.0 -0.57 -1.3161 -0.934 3628378 CBKinase1_018208 CC1=C(C(c2ccccc2OCc3ccccc3)n4ncnc4N1)C(=O)Nc5ccccc5C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C05 compound treatment 2043004.0 -1420000.0 -1.2 3244833.0 -133000.0 -0.11 -0.9241 -0.7666 1984399 CBKinase1_018209 CN(C)S(=O)(=O)n1nc(C)nc1c2ccccc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C06 compound treatment 1816629.0 -1650000.0 -1.39 3146467.0 -231000.0 -0.18 -1.1145 -0.7939 3628379 CBKinase1_018210 COc1ccc(cc1NC(=O)COc2ccc(cc2Br)C(C)(C)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C07 compound treatment 2439891.0 -1030000.0 -0.87 3395784.0 17800.0 0.01 -0.6023 -0.6954 2068992 CBKinase1_018211 CN(CCc1ccccn1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C08 compound treatment 2240770.0 -1230000.0 -1.03 3533426.0 155000.0 0.12 -0.6435 -0.6179 3628380 CBKinase1_018212 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)N4CCCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C09 compound treatment 2400000.0 -1070000.0 -0.9 3365121.0 -12800.0 -0.01 -0.6433 -0.7151 3628381 CBKinase1_018213 NC(=O)c1ccc(cc1)n2nnnc2SCC(=O)Nc3ccccc3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C10 compound treatment 2127117.0 -1340000.0 -1.13 3271768.0 -106000.0 -0.08 -0.8587 -0.7579 3628382 CBKinase1_018214 Brc1cccc(CNc2nc3ccccc3n2CCN4CCOCC4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C11 mock treatment 2403523.0 -1060000.0 -0.9 3659511.0 282000.0 0.22 -0.4753 -0.5143 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C12 mock treatment 2335660.0 -1130000.0 -0.95 3580689.0 203000.0 0.16 -0.5602 -0.5791 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C13 compound treatment 2762684.0 -704000.0 -0.59 3723664.0 346000.0 0.28 -0.225 -0.3437 3628383 CBKinase1_018215 Fc1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C14 compound treatment 3016170.0 -450000.0 -0.38 3686962.0 309000.0 0.25 -0.0945 -0.2086 3628384 CBKinase1_018216 Cc1nc(SCC(=O)N2CCc3ccccc23)c4c5CCCCc5sc4n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C15 mock treatment 3262625.0 -204000.0 -0.17 3612569.0 235000.0 0.19 0.0106 0.0418 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C16 mock treatment 3116127.0 -350000.0 -0.3 3754218.0 376000.0 0.3 0.0031 0.0073 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C17 compound treatment 3630105.0 164000.0 0.14 3739531.0 362000.0 0.29 0.3014 0.9431 3628385 CBKinase1_018217 CCn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C18 compound treatment 3373073.0 -93500.0 -0.08 3979348.0 601000.0 0.48 0.2832 0.583 3628386 CBKinase1_018218 Cc1cc(Br)c(NC(=O)CSc2nnc(N)s2)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C19 compound treatment 3670020.0 203000.0 0.17 4365671.0 988000.0 0.79 0.6781 0.8415 3628387 CBKinase1_018219 O=C(NCCN1CCOCC1)c2cccc(c2)S(=O)(=O)N3CCCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C20 compound treatment 3480430.0 13900.0 0.01 4585475.0 1210000.0 0.96 0.6889 0.7157 3628388 CBKinase1_018220 Cc1c(F)cccc1NC(=O)CCC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C21 compound treatment 3630672.0 164000.0 0.14 4400504.0 1020000.0 0.82 0.6742 0.8155 3628389 CBKinase1_018221 [O-][N+](=O)c1ccccc1NC(=O)CN2C(=O)CN(C2=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C22 compound treatment 3340272.0 -126000.0 -0.11 3866732.0 489000.0 0.39 0.2002 0.4956 1849854 CBKinase1_018222 Nc1nnc(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C23 compound treatment 3519819.0 53300.0 0.04 3797723.0 420000.0 0.33 0.2684 0.795 3628390 CBKinase1_018223 COc1ccc(OC)c(c1)S(=O)(=O)ON2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 C24 compound treatment 3054323.0 -412000.0 -0.35 3423415.0 45500.0 0.04 -0.2202 -0.63 3628391 CBKinase1_018224 Cc1cc2nn(nc2cc1NC(=O)COc3ccc(cc3)[N+](=O)[O-])c4cccc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D01 compound treatment 2823105.0 -643000.0 -0.54 2273068.0 -1100000.0 -0.88 -1.0065 -0.973 3628392 CBKinase1_018225 Cc1cccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c4ccccc24)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D02 compound treatment 3238833.0 -228000.0 -0.19 2695040.0 -683000.0 -0.54 -0.5207 -0.9021 3628393 CBKinase1_018226 C(Nc1ncnc2sc(cc12)c3ccccc3)C4CCCO4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D03 compound treatment 3432921.0 -33600.0 -0.03 3414612.0 36700.0 0.03 6.0E-4 0.0153 3628394 CBKinase1_018227 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)NCC4CCCO4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D04 compound treatment 3689241.0 223000.0 0.19 3683587.0 306000.0 0.24 0.3051 0.9918 3628395 CBKinase1_018228 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D05 compound treatment 3522008.0 55500.0 0.05 3124820.0 -253000.0 -0.2 -0.1096 -0.529 3628396 CBKinase1_018229 Fc1ccccc1n2c(CSc3nc4ccccc4c(=O)[nH]3)nc5c(Cl)cc(Cl)cc5c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D06 compound treatment 3558675.0 92100.0 0.08 3313409.0 -64500.0 -0.05 0.0186 0.1994 3117824 CBKinase1_018230 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CSc4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D07 compound treatment 3651247.0 185000.0 0.16 3318931.0 -59000.0 -0.05 0.0769 0.4726 3628397 CBKinase1_018231 COc1ccc(NC(=O)CSc2ncccn2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D08 compound treatment 3250842.0 -216000.0 -0.18 3175616.0 -202000.0 -0.16 -0.2427 -0.9982 1986345 CBKinase1_018232 Cc1nnc(SCc2cc(=O)[nH]c(Nc3nc(C)c4cc(C)ccc4n3)n2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D09 compound treatment 3922647.0 456000.0 0.38 3430720.0 52800.0 0.04 0.3018 0.7798 3628398 CBKinase1_018233 CCOc1ccc(NC(=O)Cn2cncc2c3ccc(cc3)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D10 compound treatment 4005651.0 539000.0 0.45 3888750.0 511000.0 0.41 0.6094 0.9985 3628399 CBKinase1_018234 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D11 mock treatment 3980124.0 514000.0 0.43 4141735.0 764000.0 0.61 0.7368 0.9861 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D12 mock treatment 4021136.0 555000.0 0.47 4337892.0 960000.0 0.77 0.8718 0.9721 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D13 compound treatment 3912347.0 446000.0 0.38 4059270.0 681000.0 0.54 0.6499 0.9839 3628400 CBKinase1_018235 Nc1cc(N)nc(SCC(=O)Nc2cccc(Cl)c2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D14 compound treatment 3881524.0 415000.0 0.35 3691352.0 313000.0 0.25 0.4242 0.9863 3628401 CBKinase1_018236 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C(C)Oc2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D15 mock treatment 3670756.0 204000.0 0.17 4294767.0 917000.0 0.73 0.6385 0.8505 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D16 mock treatment 4241630.0 775000.0 0.65 3678280.0 300000.0 0.24 0.6316 0.9071 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D17 compound treatment 4104070.0 638000.0 0.54 4285119.0 907000.0 0.72 0.8915 0.9894 3628402 CBKinase1_018237 COc1ccc(NC(=O)CS(=O)(=O)Cc2ccccc2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D18 compound treatment 3484200.0 17700.0 0.01 4148112.0 770000.0 0.61 0.4446 0.7241 3628403 CBKinase1_018238 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(CC(=O)Nc2ccccc2C(F)(F)F)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D19 compound treatment 3907338.0 441000.0 0.37 4775283.0 1400000.0 1.11 1.0505 0.8946 3628404 CBKinase1_018239 CN(CC(=O)Nc1c(C)cc(C)cc1C)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D20 compound treatment 3952295.0 486000.0 0.41 4408405.0 1030000.0 0.82 0.8705 0.9484 3628405 CBKinase1_018240 Fc1cccc(NC(=O)C(=O)NCCN2CCOCC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D21 compound treatment 4047949.0 581000.0 0.49 4489264.0 1110000.0 0.89 0.9731 0.9611 3628406 CBKinase1_018241 COc1nc(OCCNS(=O)(=O)c2ccc(C)cc2)nc(n1)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D22 compound treatment 4155517.0 689000.0 0.58 4576429.0 1200000.0 0.96 1.0864 0.9716 3118712 CBKinase1_018242 FC(F)(F)c1ccccc1NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D23 compound treatment 3633876.0 167000.0 0.14 3967635.0 590000.0 0.47 0.4322 0.8806 3628407 CBKinase1_018243 CSc1ccccc1NC(=O)CN(Cc2ccccc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 D24 compound treatment 3325660.0 -141000.0 -0.12 3681872.0 304000.0 0.24 0.0873 0.3235 3628408 CBKinase1_018244 COc1ccc(OC(C)c2nc(no2)c3ccc(OC)c(OC)c3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E01 mock treatment 1050042.0 -2420000.0 -2.04 1440244.0 -1940000.0 -1.54 -2.5334 -0.9906 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E02 mock treatment 1391832.0 -2070000.0 -1.75 2306442.0 -1070000.0 -0.85 -1.8413 -0.9456 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E03 compound treatment 1164373.0 -2300000.0 -1.94 1551813.0 -1830000.0 -1.46 -2.4023 -0.9899 3628409 CBKinase1_018245 COc1ccc(OC(C)C(=O)Nc2ccc(cc2)C(=O)N)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E04 compound treatment 1625958.0 -1840000.0 -1.55 2179773.0 -1200000.0 -0.95 -1.7731 -0.9728 3628410 CBKinase1_018246 Cc1sc2nc(C)nc(SCC(=O)NCc3ccccc3)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E05 compound treatment 1188680.0 -2280000.0 -1.92 2181612.0 -1200000.0 -0.95 -2.0329 -0.9477 3628411 CBKinase1_018247 CCn1c(SCC(=O)c2ccc(F)cc2)nnc1c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E06 compound treatment 1394824.0 -2070000.0 -1.75 2512022.0 -866000.0 -0.69 -1.7237 -0.9174 3628412 CBKinase1_018248 COc1ccc(OC(C)C(=O)Nc2cccnc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E07 compound treatment 1317893.0 -2150000.0 -1.81 2111417.0 -1270000.0 -1.01 -1.9953 -0.9618 3628413 CBKinase1_018249 O=C(CS(=O)(=O)Cc1ccccc1)Nc2ccccc2C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E08 compound treatment 1686984.0 -1780000.0 -1.5 2593389.0 -785000.0 -0.63 -1.5036 -0.9247 3628414 CBKinase1_018250 Cc1sc2nc(C)nc(SCC(=O)NCc3ccco3)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E09 mock treatment 1556994.0 -1910000.0 -1.61 2293228.0 -1080000.0 -0.86 -1.7503 -0.9574 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E10 mock treatment 1608391.0 -1860000.0 -1.57 2586816.0 -791000.0 -0.63 -1.5541 -0.9199 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E11 compound treatment 1699172.0 -1770000.0 -1.49 2288608.0 -1090000.0 -0.87 -1.6681 -0.9669 3628415 CBKinase1_018251 COC(=O)c1ccccc1NC(=O)Cn2c(=O)oc3ccc(Cl)cc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E12 compound treatment 1672837.0 -1790000.0 -1.51 2517410.0 -861000.0 -0.69 -1.5548 -0.936 3628416 CBKinase1_018252 CCN(CC)CCn1c2ccccc2c3nnc(S)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E13 compound treatment 2105228.0 -1360000.0 -1.15 2399390.0 -979000.0 -0.78 -1.3634 -0.9822 3118710 CBKinase1_018253 CCC1(C2c3cc(Br)ccc3OC(=O)C21C(=O)c4ccco4)C(=O)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E14 compound treatment 2813676.0 -653000.0 -0.55 2460178.0 -918000.0 -0.73 -0.9066 -0.9902 3628417 CBKinase1_018254 CN(CC(=O)Nc1ccccc1Cl)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E15 compound treatment 3008646.0 -458000.0 -0.39 2569033.0 -809000.0 -0.64 -0.729 -0.97 3628418 CBKinase1_018255 Cc1cccc(NC(=O)CCn2cnc3ccccc3c2=O)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E16 compound treatment 2935815.0 -531000.0 -0.45 2403264.0 -975000.0 -0.78 -0.8659 -0.9657 3628419 CBKinase1_018256 Cn1c(SCC(=O)NCCO)nc2ccccc2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E17 mock treatment 2730266.0 -736000.0 -0.62 2485773.0 -892000.0 -0.71 -0.942 -0.9977 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E18 mock treatment 2585663.0 -881000.0 -0.74 2353217.0 -1020000.0 -0.82 -1.1029 -0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E19 compound treatment 2719550.0 -747000.0 -0.63 2450900.0 -927000.0 -0.74 -0.968 -0.9969 3628420 CBKinase1_018257 COc1ccccc1c2nc(SCC(=O)N3CCOCC3)n[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E20 compound treatment 2733703.0 -733000.0 -0.62 2370174.0 -1010000.0 -0.8 -1.0051 -0.9916 3628421 CBKinase1_018258 O=C(CSc1nc(Nc2ccccc2)nc(Nc3ccccc3)n1)N4CCN(CC4)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E21 compound treatment 2857781.0 -609000.0 -0.51 2442215.0 -936000.0 -0.75 -0.8905 -0.9834 3628422 CBKinase1_018259 Fc1cccc(c1)N2C(=O)CC(SCCc3nc4ccccc4[nH]3)C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E22 compound treatment 2520579.0 -946000.0 -0.8 2624542.0 -753000.0 -0.6 -0.9888 -0.9902 3628423 CBKinase1_018260 Cc1cc(ccc1F)S(=O)(=O)NCC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E23 compound treatment 2750420.0 -716000.0 -0.6 3926369.0 548000.0 0.44 -0.118 -0.1583 3628424 CBKinase1_018261 COc1ccccc1OCCCn2cc(C(=O)c3ccccc3)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 E24 compound treatment 2232247.0 -1230000.0 -1.04 1887795.0 -1490000.0 -1.19 -1.576 -0.9978 3628425 CBKinase1_018262 COc1ccc(cc1OC)c2nnc(SCC(=O)O)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F01 mock treatment 1426312.0 -2040000.0 -1.72 1459053.0 -1920000.0 -1.53 -2.2983 -0.9983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F02 mock treatment 1648239.0 -1820000.0 -1.53 1971510.0 -1410000.0 -1.12 -1.8772 -0.9881 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F03 compound treatment 2103891.0 -1360000.0 -1.15 1830005.0 -1550000.0 -1.23 -1.6851 -0.9994 3628426 CBKinase1_018263 CC(C)(C)c1ccc(OCC(=O)NCc2cccnc2)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F04 compound treatment 2134708.0 -1330000.0 -1.12 2326271.0 -1050000.0 -0.84 -1.3871 -0.9896 3628427 CBKinase1_018264 CCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F05 compound treatment 2319229.0 -1150000.0 -0.97 2055288.0 -1320000.0 -1.05 -1.4297 -0.9991 3628428 CBKinase1_018265 COc1cccc(Nc2nc(cs2)C3(C)CC4(CC(C)OC4=O)C(=O)O3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F06 compound treatment 2476678.0 -990000.0 -0.83 2225415.0 -1150000.0 -0.92 -1.2399 -0.9989 3085378 CBKinase1_018266 CN(C)c1nc(N)nc(Cn2ccnc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F07 compound treatment 2201680.0 -1260000.0 -1.07 1987607.0 -1390000.0 -1.11 -1.538 -0.9998 3628429 CBKinase1_018267 COc1ccccc1NC(=O)CSc2nnc(c3ccccc3)n2c4cccc(C)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F08 compound treatment 2563736.0 -903000.0 -0.76 2160254.0 -1220000.0 -0.97 -1.2247 -0.9928 3628430 CBKinase1_018268 Cc1nnc(SCC(=O)N2CCc3ccccc23)n1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F09 mock treatment 3052182.0 -414000.0 -0.35 1988961.0 -1390000.0 -1.11 -1.03 -0.8872 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F10 mock treatment 2188482.0 -1280000.0 -1.08 2180370.0 -1200000.0 -0.95 -1.4372 -0.9982 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F11 compound treatment 2646975.0 -820000.0 -0.69 2507402.0 -871000.0 -0.69 -0.9794 -1.0 3628431 CBKinase1_018269 COc1ccc(cc1Br)C(=O)CSc2[nH]c(C)nc2[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F12 compound treatment 2385644.0 -1080000.0 -0.91 2210814.0 -1170000.0 -0.93 -1.3025 -0.9999 3628432 CBKinase1_018270 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F13 compound treatment 2468176.0 -998000.0 -0.84 2151917.0 -1230000.0 -0.98 -1.2864 -0.9973 3628433 CBKinase1_018271 COc1ccc(cc1S(=O)(=O)N)c2nnc3c4ccccc4c(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F14 compound treatment 2594764.0 -872000.0 -0.74 2110666.0 -1270000.0 -1.01 -1.2342 -0.9878 3628434 CBKinase1_018272 COC(=O)c1ccccc1NC(=O)CSc2nnnn2c3cccc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F15 compound treatment 2622450.0 -844000.0 -0.71 2153932.0 -1220000.0 -0.98 -1.1933 -0.988 3628435 CBKinase1_018273 Cc1ccc(CN(CC(=O)O)S(=O)(=O)c2c(C)cc(C)cc2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F16 compound treatment 2414357.0 -1050000.0 -0.89 1960523.0 -1420000.0 -1.13 -1.4264 -0.9929 2069016 CBKinase1_018274 Cc1sc2c(c1C)c(=O)nc3scc(CC(=O)NCCO)n32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F17 mock treatment 2591657.0 -875000.0 -0.74 2328746.0 -1050000.0 -0.84 -1.1131 -0.9981 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F18 mock treatment 2358562.0 -1110000.0 -0.93 2300975.0 -1080000.0 -0.86 -1.2678 -0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F19 compound treatment 2815839.0 -651000.0 -0.55 2408380.0 -970000.0 -0.77 -0.9345 -0.9859 3628436 CBKinase1_018275 O=C(CSc1nnc(c2cccs2)n1c3ccccc3)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F20 compound treatment 3173902.0 -293000.0 -0.25 1959174.0 -1420000.0 -1.13 -0.9741 -0.8416 3628437 CBKinase1_018276 CCn1c(SCC(=O)Nc2ccc(Br)cc2Cl)nnc1c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F21 compound treatment 2992159.0 -474000.0 -0.4 2062911.0 -1320000.0 -1.05 -1.0241 -0.9128 3628438 CBKinase1_018277 CN(CC(=O)Nc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F22 compound treatment 3139520.0 -327000.0 -0.28 2564193.0 -814000.0 -0.65 -0.6537 -0.9274 3628439 CBKinase1_018278 COc1ccc(Nc2nc(N)nc(CSc3nccn3C)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F23 compound treatment 2450767.0 -1020000.0 -0.86 2504475.0 -873000.0 -0.7 -1.0981 -0.9947 3628440 CBKinase1_018279 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C(C)Oc2ccc(OC)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 F24 compound treatment 2295362.0 -1170000.0 -0.99 2023259.0 -1350000.0 -1.08 -1.462 -0.999 3628441 CBKinase1_018280 CC(C)CC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)Nc3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G01 compound treatment 1431582.0 -2030000.0 -1.72 2732344.0 -646000.0 -0.51 -1.5776 -0.8804 3628442 CBKinase1_018281 CN(CC(=O)Nc1ccc(Nc2ccccc2)cc1)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G02 compound treatment 1396665.0 -2070000.0 -1.75 2783734.0 -594000.0 -0.47 -1.5694 -0.8676 3628443 CBKinase1_018282 OC(=O)CSc1nnc(c2ccncc2)n1c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G03 mock treatment 1701181.0 -1770000.0 -1.49 3084398.0 -294000.0 -0.23 -1.2184 -0.8083 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G04 mock treatment 1818718.0 -1650000.0 -1.39 2818091.0 -560000.0 -0.45 -1.2984 -0.8894 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G05 compound treatment 2008672.0 -1460000.0 -1.23 3062150.0 -316000.0 -0.25 -1.0475 -0.8345 3628444 CBKinase1_018283 Nc1cc(N)nc(SCC(=O)N2CCN(CC2)c3ccc(Cl)cc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G06 compound treatment 1847587.0 -1620000.0 -1.37 3989163.0 611000.0 0.49 -0.6211 -0.4284 3628445 CBKinase1_018284 OC(=O)CC(Cn1nnnc1S)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G07 compound treatment 1799195.0 -1670000.0 -1.41 3264672.0 -113000.0 -0.09 -1.0583 -0.751 3628446 CBKinase1_018285 CCn1c(NCCCO)nc2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G08 compound treatment 1987085.0 -1480000.0 -1.25 3092614.0 -285000.0 -0.23 -1.0432 -0.8224 3628447 CBKinase1_018286 CCOC(=O)c1c(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCCC3)sc4CCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G09 compound treatment 2071825.0 -1390000.0 -1.18 3196515.0 -181000.0 -0.14 -0.9341 -0.7881 3628448 CBKinase1_018287 Cc1cc(OCC(=O)Nc2cccnc2)ccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G10 compound treatment 1966401.0 -1500000.0 -1.27 3167149.0 -211000.0 -0.17 -1.0135 -0.794 3628449 CBKinase1_018288 COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G11 compound treatment 2055681.0 -1410000.0 -1.19 2983729.0 -394000.0 -0.31 -1.0637 -0.8642 3628450 CBKinase1_018289 Cc1sc2nc(C)nc(SCC(=O)Nc3ccccc3[N+](=O)[O-])c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G12 compound treatment 2192824.0 -1270000.0 -1.07 3324651.0 -53300.0 -0.04 -0.7897 -0.7345 3628451 CBKinase1_018290 COc1ccc(cc1NC(=O)CS(=O)(=O)Cc2ccccc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G13 compound treatment 2248142.0 -1220000.0 -1.03 3458106.0 80200.0 0.06 -0.6815 -0.6619 3628452 CBKinase1_018291 Cc1cc(Oc2ccccc2)nc(SCC(=O)N)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G14 compound treatment 2025271.0 -1440000.0 -1.22 3364528.0 -13400.0 -0.01 -0.8672 -0.7133 3628453 CBKinase1_018292 Cn1c(SCc2nc(no2)c3ccc(Cl)cc3)nnc1c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G15 compound treatment 2516183.0 -950000.0 -0.8 3603198.0 225000.0 0.18 -0.4399 -0.5355 3628454 CBKinase1_018293 Nc1cccc(c1)c2nnc(SCC(=O)c3ccc(F)cc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G16 compound treatment 2495254.0 -971000.0 -0.82 3489710.0 112000.0 0.09 -0.5163 -0.6265 3628455 CBKinase1_018294 Cc1ccc(CCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G17 compound treatment 2844662.0 -622000.0 -0.52 3359314.0 -18600.0 -0.01 -0.3814 -0.7268 3628456 CBKinase1_018295 CC(C)(C)c1ccc(OCC(=O)Nc2cccnc2)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G18 compound treatment 2847616.0 -619000.0 -0.52 3410440.0 32500.0 0.03 -0.3508 -0.6712 3628457 CBKinase1_018296 COc1ccccc1c2nc(SCc3ccc(cc3)C(=O)O)n[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G19 mock treatment 3286925.0 -180000.0 -0.15 3508147.0 130000.0 0.1 -0.0337 -0.1837 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G20 mock treatment 3230649.0 -236000.0 -0.2 3625602.0 248000.0 0.2 -0.0011 -0.004 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G21 compound treatment 3186867.0 -280000.0 -0.24 3616000.0 238000.0 0.19 -0.0326 -0.1078 3628458 CBKinase1_018297 COc1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1S(=O)(=O)N5CCCCCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G22 compound treatment 3334506.0 -132000.0 -0.11 3537728.0 160000.0 0.13 0.0113 0.0669 3628459 CBKinase1_018298 Cc1nc(SCC(=O)c2ccc(Cl)cc2)c3c4CCCCc4sc3n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G23 compound treatment 3215630.0 -251000.0 -0.21 3461519.0 83600.0 0.07 -0.1025 -0.4622 3628460 CBKinase1_018299 CN(CC(=O)Nc1ccc(Cl)c(Cl)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 G24 compound treatment 3050830.0 -416000.0 -0.35 3023555.0 -354000.0 -0.28 -0.4477 -0.9943 3628461 CBKinase1_018300 Cc1cc(C)c(OCC(=O)Nc2ccc3oc(nc3c2)c4cncc(Br)c4)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H01 compound treatment 2474271.0 -992000.0 -0.84 2408452.0 -969000.0 -0.77 -1.1382 -0.9992 3628462 CBKinase1_018301 COC(=O)c1c(NC(=O)C2CC(=O)NN2Cc3ccccc3)sc4CC(C)CCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H02 compound treatment 3396603.0 -69900.0 -0.06 2753703.0 -624000.0 -0.5 -0.3935 -0.7854 3628463 CBKinase1_018302 CC(C)c1ccccc1OCC(=O)Nc2sc(C)c(C)c2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H03 mock treatment 3669976.0 203000.0 0.17 3139775.0 -238000.0 -0.19 -0.0129 -0.0504 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H04 mock treatment 3839191.0 373000.0 0.31 3860468.0 483000.0 0.38 0.4942 0.995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H05 compound treatment 3625836.0 159000.0 0.13 2924547.0 -453000.0 -0.36 -0.1605 -0.4163 3628464 CBKinase1_018303 COC(=O)c1ccccc1NC(=O)CN(C2CCCCC2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H06 compound treatment 3880024.0 413000.0 0.35 3315125.0 -62800.0 -0.05 0.2112 0.5995 1671084 CBKinase1_018304 O=C(CSc1nnnn1c2ccccc2)Nc3ccc(Oc4ccccc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H07 compound treatment 3805307.0 339000.0 0.29 3087888.0 -290000.0 -0.23 0.0386 0.105 3628465 CBKinase1_018305 CC(C)c1ccccc1OCC(=O)Nc2ccccc2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H08 compound treatment 3686305.0 220000.0 0.19 3244195.0 -134000.0 -0.11 0.0557 0.2605 1351774 CBKinase1_018306 CCN1CCN(Cc2c(C)nc3ccc(cc3c2O)C(=O)OC)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H09 compound treatment 4162729.0 696000.0 0.59 2911090.0 -467000.0 -0.37 0.1521 0.2188 2068766 CBKinase1_018307 Cc1sc2nc(SCCC(=O)NC3CCCCC3)[nH]c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H10 compound treatment 4077220.0 611000.0 0.52 3445774.0 67800.0 0.05 0.4025 0.7771 2085433 CBKinase1_018308 CN(CC(=O)O)S(=O)(=O)c1ccc2ccccc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H11 compound treatment 3942992.0 476000.0 0.4 3573934.0 196000.0 0.16 0.3946 0.9152 3628466 CBKinase1_018309 COc1cccc(c1)C2=NN(C(C2)c3ccco3)C(=O)c4onc(c4C)c5ccccc5Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H12 compound treatment 4624916.0 1160000.0 0.98 3504252.0 126000.0 0.1 0.7621 0.7759 3628467 CBKinase1_018310 OC(=O)COc1ccc(NC(=O)c2ccccc2c3ccccc3C(=O)O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H13 compound treatment 4437967.0 971000.0 0.82 3194922.0 -183000.0 -0.15 0.4763 0.5722 3628468 CBKinase1_018311 [O-][N+](=O)c1cccc(c1)c2nn(CC(=O)Nc3cccc(Cl)c3)c(=O)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H14 compound treatment 4689011.0 1220000.0 1.03 3687902.0 310000.0 0.25 0.9038 0.8524 3628469 CBKinase1_018312 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)CS(=O)(=O)Cc4ccccc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H15 compound treatment 4318123.0 852000.0 0.72 3551813.0 174000.0 0.14 0.6059 0.8283 3628470 CBKinase1_018313 Cc1cc(=O)[nH]c(SCC(=O)Nc2cccc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H16 compound treatment 4182996.0 716000.0 0.6 3943490.0 566000.0 0.45 0.7461 0.9896 3628471 CBKinase1_018314 CC(C)(C)NC(=O)CN(c1ccc2CCc3cccc1c32)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H17 compound treatment 4565834.0 1100000.0 0.93 3553636.0 176000.0 0.14 0.7547 0.8048 3628472 CBKinase1_018315 Cc1nn(c(OC(=O)c2cccc(Br)c2)c1S(=O)(=O)c3ccccc3)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H18 compound treatment 4626552.0 1160000.0 0.98 3887054.0 509000.0 0.41 0.9788 0.924 3628473 CBKinase1_018316 Cc1c(Cl)cccc1NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H19 mock treatment 4196685.0 730000.0 0.62 3105555.0 -272000.0 -0.22 0.282 0.4318 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H20 mock treatment 5139031.0 1670000.0 1.41 4036149.0 658000.0 0.52 1.3685 0.9092 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H21 compound treatment 4757191.0 1290000.0 1.09 3981236.0 603000.0 0.48 1.1098 0.9325 3628474 CBKinase1_018317 Cc1ccc(NC(=O)CSc2nc(C)cc(n2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H22 compound treatment 4820979.0 1350000.0 1.14 4239105.0 861000.0 0.69 1.2932 0.9703 3628475 CBKinase1_018318 CCOc1ccc(NC(=O)CSc2nc(C)nc3sc4CCCCc4c23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H23 compound treatment 4277286.0 811000.0 0.68 3733270.0 355000.0 0.28 0.6838 0.9239 3628476 CBKinase1_018319 OC(=O)CSc1nnc(C2CC2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 H24 compound treatment 3572688.0 106000.0 0.09 2947890.0 -430000.0 -0.34 -0.1791 -0.5054 3628477 CBKinase1_018320 CC(C)(C)c1ccc(OCC(=O)NCc2ccccn2)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I01 compound treatment 1798622.0 -1670000.0 -1.41 2810178.0 -568000.0 -0.45 -1.3148 -0.8897 3628478 CBKinase1_018321 O=C(NCCN1CCNCC1)c2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I02 compound treatment 1791235.0 -1680000.0 -1.41 3685226.0 307000.0 0.24 -0.826 -0.576 3628479 CBKinase1_018322 Clc1c(sc2ccccc12)C(=O)Nc3nonc3NC(=O)c4sc5ccccc5c4Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I03 compound treatment 1907426.0 -1560000.0 -1.32 4088118.0 710000.0 0.57 -0.5297 -0.3699 3628480 CBKinase1_018323 COc1ccc(OC)c(NC(=O)CSc2nnc(c3ccc(C)c(Cl)c3)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I04 compound treatment 1918366.0 -1550000.0 -1.31 3493963.0 116000.0 0.09 -0.858 -0.6554 3628481 CBKinase1_018324 COc1ccc(OC(C)C(=O)Nc2ccc(OC)c(OC)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I05 mock treatment 1934757.0 -1530000.0 -1.29 3667156.0 289000.0 0.23 -0.7506 -0.5719 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I06 mock treatment 1952421.0 -1510000.0 -1.28 3902306.0 524000.0 0.42 -0.6075 -0.4521 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I07 compound treatment 2176402.0 -1290000.0 -1.09 3592526.0 215000.0 0.17 -0.6485 -0.5887 3628482 CBKinase1_018325 CN(CC(=O)Nc1ccccc1C(=O)N)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I08 compound treatment 2429627.0 -1040000.0 -0.87 3705241.0 327000.0 0.26 -0.434 -0.4755 3628483 CBKinase1_018326 COc1ccc(OC)c(NC(=O)c2ccc(CSc3nnnn3C)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I09 compound treatment 2581421.0 -885000.0 -0.75 3145564.0 -232000.0 -0.19 -0.6589 -0.8566 3628484 CBKinase1_018327 COc1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1S(=O)(=O)N5CCOCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I10 compound treatment 2550969.0 -916000.0 -0.77 3772068.0 394000.0 0.31 -0.324 -0.3886 3628485 CBKinase1_018328 Cn1c(CN2CCOCC2)nnc1SCC(=O)Nc3sc4CC(CCc4c3C#N)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I11 compound treatment 3117059.0 -349000.0 -0.29 3802954.0 425000.0 0.34 0.0311 0.0692 3124171 CBKinase1_018329 COC(=O)CC1=Nc2ccccc2NC(=O)C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I12 compound treatment 2993668.0 -473000.0 -0.4 4199798.0 822000.0 0.66 0.1812 0.2362 2068788 CBKinase1_018330 COC(=O)CSc1nnc(c2cccs2)n1c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I13 compound treatment 2974209.0 -492000.0 -0.42 3794563.0 417000.0 0.33 -0.0588 -0.1107 3628486 CBKinase1_018331 CN(Cc1nc(no1)c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I14 compound treatment 2866007.0 -601000.0 -0.51 3969999.0 592000.0 0.47 -0.0245 -0.0354 3628487 CBKinase1_018332 COc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I15 compound treatment 2889855.0 -577000.0 -0.49 4365548.0 988000.0 0.79 0.2127 0.2298 3628488 CBKinase1_018333 O=C(CS(=O)(=O)Cc1ccccc1)Nc2ncccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I16 compound treatment 2888712.0 -578000.0 -0.49 3716254.0 338000.0 0.27 -0.154 -0.2764 3628489 CBKinase1_018334 Cc1nnc(SCc2ccccc2C#N)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I17 compound treatment 2814586.0 -652000.0 -0.55 3920488.0 543000.0 0.43 -0.0831 -0.1187 3628490 CBKinase1_018335 Cc1cc(=O)[nH]c(SCc2cnc(C)nc2N)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I18 compound treatment 2606702.0 -860000.0 -0.73 3779004.0 401000.0 0.32 -0.2868 -0.3619 3628491 CBKinase1_018336 CS(=O)(=O)N(CC(=O)N1CCOCC1)c2ccc3CCc4cccc2c43 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I19 compound treatment 3281711.0 -185000.0 -0.16 3148134.0 -230000.0 -0.18 -0.2398 -0.9968 3628492 CBKinase1_018337 Cc1nc(C)c(s1)C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I20 compound treatment 3578204.0 112000.0 0.09 4070725.0 693000.0 0.55 0.4571 0.8159 1720868 CBKinase1_018338 COc1ccc(NC(=O)CSc2nnnn2C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I21 mock treatment 3366910.0 -99600.0 -0.08 4154138.0 776000.0 0.62 0.378 0.6055 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I22 mock treatment 4142861.0 676000.0 0.57 4156782.0 779000.0 0.62 0.8423 0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I23 compound treatment 4068772.0 602000.0 0.51 3985151.0 607000.0 0.48 0.7014 0.9997 3628493 CBKinase1_018339 CCn1c(SCC(=O)N2CCc3ccccc23)nnc1c4ccncc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 I24 compound treatment 3529538.0 63000.0 0.05 2819032.0 -559000.0 -0.45 -0.2774 -0.6184 3027236 CBKinase1_018340 COc1ccccc1Nc2nc(N)nc(CN3CCc4ccccc4C3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J01 compound treatment 3605905.0 139000.0 0.12 2993012.0 -385000.0 -0.31 -0.1338 -0.4073 3628494 CBKinase1_018341 COc1ccc(OC(C)c2nc(no2)c3ccccn3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J02 compound treatment 3967877.0 501000.0 0.42 3115599.0 -262000.0 -0.21 0.1512 0.3204 3628495 CBKinase1_018342 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc4c5ccccc5c(C)nn34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J03 compound treatment 3867960.0 401000.0 0.34 3463552.0 85600.0 0.07 0.2877 0.8329 3628496 CBKinase1_018343 CN(Cc1nc(no1)c2cccnc2)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J04 compound treatment 3765006.0 298000.0 0.25 3615416.0 237000.0 0.19 0.3119 0.9901 3628497 CBKinase1_018344 COc1ccc(cc1OC)c2nnc(SCC(=O)c3ccc(F)cc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J05 mock treatment 4416494.0 950000.0 0.8 3792524.0 415000.0 0.33 0.8003 0.9233 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J06 mock treatment 3795248.0 329000.0 0.28 3768803.0 391000.0 0.31 0.4163 0.9983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J07 compound treatment 4077504.0 611000.0 0.52 3726599.0 349000.0 0.28 0.5609 0.958 3628498 CBKinase1_018345 CCc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J08 compound treatment 3954046.0 488000.0 0.41 3508245.0 130000.0 0.1 0.3642 0.8587 3628499 CBKinase1_018346 COc1cc(NC(=O)COc2ccc(cc2Br)C(C)(C)C)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J09 compound treatment 4451329.0 985000.0 0.83 4373638.0 996000.0 0.79 1.1485 0.9997 3628500 CBKinase1_018347 Cc1c(NC(=O)CSc2nnnn2c3ccc(O)cc3)c(=O)n(c4ccccc4)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J10 compound treatment 3661165.0 195000.0 0.16 2865392.0 -513000.0 -0.41 -0.1728 -0.3924 3628501 CBKinase1_018348 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)C(C)Oc3ccc(Cl)cc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J11 compound treatment 4310684.0 844000.0 0.71 4044435.0 666000.0 0.53 0.8791 0.9896 3628502 CBKinase1_018349 Clc1cccc(c2ccc(o2)C(=O)NC(=S)NCc3cccnc3)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J12 compound treatment 4576169.0 1110000.0 0.94 3853067.0 475000.0 0.38 0.9296 0.9207 3628503 CBKinase1_018350 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J13 compound treatment 4524241.0 1060000.0 0.89 3881538.0 504000.0 0.4 0.9147 0.935 3628504 CBKinase1_018351 [O-][N+](=O)c1ccccc1NCCNS(=O)(=O)c2ccc(Cl)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J14 compound treatment 4824433.0 1360000.0 1.15 4009354.0 631000.0 0.5 1.1658 0.9318 1986310 CBKinase1_018352 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CSc4nnc(C)s4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J15 compound treatment 4072642.0 606000.0 0.51 4011070.0 633000.0 0.5 0.7183 1.0 3628505 CBKinase1_018353 Cc1cc(C)nc(SCC(=O)N2CCN(CC2)c3nnc(c4ccccc4)c5ccccc35)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J16 compound treatment 4343822.0 877000.0 0.74 4371714.0 994000.0 0.79 1.0833 0.9994 3628506 CBKinase1_018354 Cc1ccc(CCC(=O)Nc2cc(Cl)cc(Cl)c2)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J17 compound treatment 4253837.0 787000.0 0.66 4571797.0 1190000.0 0.95 1.1424 0.9845 3628507 CBKinase1_018355 Nc1cc(N)nc(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J18 compound treatment 4371632.0 905000.0 0.76 4187612.0 810000.0 0.65 0.9962 0.9965 3628508 CBKinase1_018356 COC(=O)c1ccccc1NC(=O)Cn2c(=O)n(C)c(=O)c3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J19 compound treatment 4692920.0 1230000.0 1.03 3679995.0 302000.0 0.24 0.9017 0.849 3628509 CBKinase1_018357 Clc1ccc(NC(=O)CS(=O)(=O)Cc2ccccc2)c(c1)C(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J20 compound treatment 5017771.0 1550000.0 1.31 4563021.0 1190000.0 0.94 1.5931 0.9872 3628510 CBKinase1_018358 CN(CC(=O)Nc1ncc(cc1Cl)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J21 mock treatment 4983658.0 1520000.0 1.28 4454630.0 1080000.0 0.86 1.5117 0.9811 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J22 mock treatment 4825481.0 1360000.0 1.15 4389302.0 1010000.0 0.81 1.3805 0.9852 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J23 compound treatment 4400595.0 934000.0 0.79 3727704.0 350000.0 0.28 0.7542 0.9025 3628511 CBKinase1_018359 COc1ccc(OC(C)c2nc(no2)c3ccncc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 J24 compound treatment 3657762.0 191000.0 0.16 2735050.0 -643000.0 -0.51 -0.2483 -0.4622 3628512 CBKinase1_018360 Cc1cccc(c1)c2nnc(SCC(=O)Nc3c(F)cc(F)cc3Br)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K01 compound treatment 1355301.0 -2110000.0 -1.78 1606230.0 -1770000.0 -1.41 -2.2578 -0.9934 3628513 CBKinase1_018361 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2cccc(Br)c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K02 compound treatment 1647887.0 -1820000.0 -1.53 2723738.0 -654000.0 -0.52 -1.4534 -0.8971 3628514 CBKinase1_018362 CCOc1ccccc1C(=O)Oc2c(c(C)nn2c3ccccc3)S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K03 compound treatment 1853318.0 -1610000.0 -1.36 3116743.0 -261000.0 -0.21 -1.1094 -0.8059 3628515 CBKinase1_018363 Cc1ccc(cc1)c2nnc(N3CCN(CC3)C(=O)CSc4nc5ccccc5o4)c6ccccc26 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K04 compound treatment 1930856.0 -1540000.0 -1.3 2763060.0 -615000.0 -0.49 -1.2625 -0.9116 3027611 CBKinase1_018364 COc1ccc(cc1S(=O)(=O)NC(C)(C)C)c2nnc3c4ccccc4c(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K05 compound treatment 1934033.0 -1530000.0 -1.29 3670184.0 292000.0 0.23 -0.7493 -0.5705 3628516 CBKinase1_018365 COc1ccc(NC(=O)CSc2ccccn2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K06 compound treatment 2185477.0 -1280000.0 -1.08 3182707.0 -195000.0 -0.16 -0.8741 -0.8007 3628517 CBKinase1_018366 COc1ccc(Nc2nc(N)nc(CSc3nc(C)cc(C)n3)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K07 mock treatment 3031167.0 -435000.0 -0.37 3296171.0 -81800.0 -0.07 -0.3058 -0.8198 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K08 mock treatment 3085046.0 -381000.0 -0.32 2982397.0 -396000.0 -0.32 -0.4505 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K09 compound treatment 3503550.0 37000.0 0.03 3338452.0 -39500.0 -0.03 -2.0E-4 -0.004 3628518 CBKinase1_018367 O=C(NCCN1CCOCC1)c2cc3ccccc3o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K10 compound treatment 3629000.0 162000.0 0.14 2835712.0 -542000.0 -0.43 -0.2087 -0.4603 3087382 CBKinase1_018368 OC(=O)C1C(C2CC1C=C2)C(=O)NCCc3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K11 compound treatment 4075559.0 609000.0 0.51 2840159.0 -538000.0 -0.43 0.0602 0.0899 3628519 CBKinase1_018369 Cc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCCN5CCOCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K12 compound treatment 3758184.0 292000.0 0.25 2750564.0 -627000.0 -0.5 -0.1796 -0.3223 3628520 CBKinase1_018370 COc1ccc(cc1OC)c2nnc(SCC(=O)N)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K13 compound treatment 4058775.0 592000.0 0.5 2840194.0 -538000.0 -0.43 0.0502 0.0762 3628521 CBKinase1_018371 O=C(Cn1c(=O)oc2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K14 compound treatment 3507712.0 41200.0 0.03 2768960.0 -609000.0 -0.49 -0.3187 -0.6548 3628522 CBKinase1_018372 CCn1c(SCC(=O)Nc2ccc(F)c(Cl)c2)nnc1c3ccc(Cl)cc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K15 mock treatment 3873804.0 407000.0 0.34 3154791.0 -223000.0 -0.18 0.1171 0.3028 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K16 mock treatment 3800156.0 334000.0 0.28 3205248.0 -173000.0 -0.14 0.1017 0.3245 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K17 compound treatment 4136512.0 670000.0 0.57 3466681.0 88700.0 0.07 0.4496 0.7894 3628523 CBKinase1_018373 CCc1cc2c(NC(Cc3c[nH]c4ccccc34)C(=O)O)nc(C)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K18 compound treatment 3955306.0 489000.0 0.41 3233713.0 -144000.0 -0.11 0.2102 0.4912 1702495 CBKinase1_018374 Nc1nnc(SCC(=O)Nc2ccccc2C(=O)c3ccccc3)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K19 compound treatment 4410477.0 944000.0 0.8 2824447.0 -553000.0 -0.44 0.2511 0.2758 3628524 CBKinase1_018375 COc1ccccc1CC(=O)Nc2ccc(cc2)c3noc(n3)c4cc(OC)c(OC)c(OC)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K20 compound treatment 5178928.0 1710000.0 1.44 3005789.0 -372000.0 -0.3 0.8116 0.5504 3628525 CBKinase1_018376 [O-][N+](=O)c1ccccc1S(=O)CC(=O)Oc2ccc(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K21 compound treatment 4770274.0 1300000.0 1.1 3843416.0 465000.0 0.37 1.0399 0.896 3628526 CBKinase1_018377 COc1cccc2c(C)nc(Nc3nc(CSc4nnc(C)s4)cc(=O)[nH]3)nc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K22 compound treatment 4359582.0 893000.0 0.75 4001761.0 624000.0 0.5 0.8842 0.9797 3628527 CBKinase1_018378 N#Cc1ccccc1CSc2nnc(Cc3cccc4ccccc34)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K23 mock treatment 4379533.0 913000.0 0.77 3829614.0 452000.0 0.36 0.7991 0.94 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 K24 mock treatment 3504484.0 38000.0 0.03 2892117.0 -486000.0 -0.39 -0.2512 -0.6464 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L01 compound treatment 2473964.0 -993000.0 -0.84 2042140.0 -1340000.0 -1.06 -1.3449 -0.9929 3628528 CBKinase1_018379 Cc1ccc(cc1S(=O)(=O)N)c2nnc3c4ccccc4c(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L02 compound treatment 3125706.0 -341000.0 -0.29 2801381.0 -577000.0 -0.46 -0.5282 -0.9745 3628529 CBKinase1_018380 CN(CC(=O)Nc1ccc(Cl)cc1C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L03 compound treatment 3292989.0 -174000.0 -0.15 2953457.0 -424000.0 -0.34 -0.3427 -0.9297 3628530 CBKinase1_018381 Cc1ccc(cc1S(=O)(=O)NC2CCCCC2)c3nnc4c5ccccc5c(C)nn34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L04 compound treatment 3759586.0 293000.0 0.25 3122592.0 -255000.0 -0.2 0.0309 0.0964 3628531 CBKinase1_018382 CCc1cc2c(SCC(=O)N)ncnc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L05 compound treatment 3569517.0 103000.0 0.09 3087430.0 -291000.0 -0.23 -0.1023 -0.4137 3212214 CBKinase1_018383 O=C(NCCCn1ccnc1)c2cc3ccccc3o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L06 compound treatment 3656428.0 190000.0 0.16 3169287.0 -209000.0 -0.17 -0.0043 -0.0188 1712984 CBKinase1_018384 Cc1nc(SC(C(=O)O)c2ccccc2)cc(n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L07 mock treatment 3773499.0 307000.0 0.26 3098254.0 -280000.0 -0.22 0.0255 0.0745 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L08 mock treatment 3341082.0 -125000.0 -0.11 3321588.0 -56400.0 -0.04 -0.1066 -0.9272 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L09 compound treatment 3580246.0 114000.0 0.1 3164802.0 -213000.0 -0.17 -0.0523 -0.2681 3628532 CBKinase1_018385 Cc1ccc(C)c(NC(=O)CSc2nnnn2c3ccc(cc3)C(=O)O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L10 compound treatment 3495298.0 28800.0 0.02 3028588.0 -349000.0 -0.28 -0.1797 -0.643 3628533 CBKinase1_018386 O=C1N(CCCc2nc(no2)c3ccccn3)C(=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L11 compound treatment 3875199.0 409000.0 0.34 3031519.0 -346000.0 -0.28 0.0485 0.1098 3628534 CBKinase1_018387 CSc1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L12 compound treatment 3866162.0 400000.0 0.34 3693898.0 316000.0 0.25 0.4164 0.9897 3628535 CBKinase1_018388 CS(=O)(=O)CCC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L13 compound treatment 3949422.0 483000.0 0.41 3625767.0 248000.0 0.2 0.4277 0.9448 3628536 CBKinase1_018389 Oc1ccc(cc1O)C(=O)CSc2nnnn2c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L14 compound treatment 3758634.0 292000.0 0.25 2420929.0 -957000.0 -0.76 -0.3651 -0.4555 3628537 CBKinase1_018390 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc2ccc(cc2)C3CCCCC3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L15 mock treatment 4423421.0 957000.0 0.81 3050510.0 -327000.0 -0.26 0.3862 0.4553 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L16 mock treatment 3837821.0 371000.0 0.31 3830742.0 453000.0 0.36 0.4767 0.9975 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L17 compound treatment 4252025.0 785000.0 0.66 3688561.0 311000.0 0.25 0.6436 0.9099 3628538 CBKinase1_018391 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L18 compound treatment 4499917.0 1030000.0 0.87 3410043.0 32100.0 0.03 0.6344 0.7275 3628539 CBKinase1_018392 Cc1c(O)nc(SC2CC(=O)N(C2=O)c3ccccc3)nc1O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L19 compound treatment 5046831.0 1580000.0 1.33 2996535.0 -381000.0 -0.3 0.7276 0.5322 3628540 CBKinase1_018393 COc1ccc(cc1)C(=O)Oc2c(c(C)nn2c3ccccc3)S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L20 compound treatment 4895733.0 1430000.0 1.21 3097388.0 -281000.0 -0.22 0.6943 0.5663 3628541 CBKinase1_018394 Cc1ccnc(SCC(=O)Nc2ccc(Cl)cc2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L21 compound treatment 3637563.0 171000.0 0.14 4228145.0 850000.0 0.68 0.5812 0.8388 3628542 CBKinase1_018395 COc1ccccc1CC(=O)Nc2ccc(cc2)c3noc(n3)c4ccc(OC)c(OC)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L22 compound treatment 4982483.0 1520000.0 1.28 4234103.0 856000.0 0.68 1.3867 0.9567 3628543 CBKinase1_018396 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L23 mock treatment 4975735.0 1510000.0 1.27 4333372.0 955000.0 0.76 1.4386 0.9698 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 L24 mock treatment 3741257.0 275000.0 0.23 2999936.0 -378000.0 -0.3 -0.0492 -0.1294 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M01 compound treatment 1607630.0 -1860000.0 -1.57 2681654.0 -696000.0 -0.55 -1.5012 -0.9025 3628544 CBKinase1_018397 Nc1nnc(SCc2ccccc2C#N)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M02 compound treatment 1822141.0 -1640000.0 -1.39 2955946.0 -422000.0 -0.34 -1.2186 -0.8538 3628545 CBKinase1_018398 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M03 compound treatment 1826499.0 -1640000.0 -1.38 3109687.0 -268000.0 -0.21 -1.1294 -0.8068 3628546 CBKinase1_018399 Cc1cccc(c1C)n2c(SCC(=O)N)nnc2c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M04 compound treatment 1796239.0 -1670000.0 -1.41 3317230.0 -60700.0 -0.05 -1.0304 -0.731 3628547 CBKinase1_018400 Cc1nnc(SCC(=O)NC2CCCCCC2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M05 compound treatment 2031093.0 -1440000.0 -1.21 3483659.0 106000.0 0.08 -0.7966 -0.6563 3628548 CBKinase1_018401 Cc1ccnc(SCC(=O)Nc2ccc(F)c(Cl)c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M06 compound treatment 2275753.0 -1190000.0 -1.0 3820457.0 443000.0 0.35 -0.4608 -0.4329 3628549 CBKinase1_018402 CC(=O)c1cccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M07 compound treatment 2636001.0 -831000.0 -0.7 3415146.0 37200.0 0.03 -0.4744 -0.6766 3628550 CBKinase1_018403 COc1ccccc1Nc2nc(N)nc(CSCCO)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M08 compound treatment 3036155.0 -430000.0 -0.36 3803676.0 426000.0 0.34 -0.0168 -0.0337 3628551 CBKinase1_018404 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M09 mock treatment 3149128.0 -317000.0 -0.27 3409064.0 31100.0 0.02 -0.1718 -0.6389 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M10 mock treatment 3371502.0 -95000.0 -0.08 3395017.0 17100.0 0.01 -0.0471 -0.5788 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M11 compound treatment 3670417.0 204000.0 0.17 3843029.0 465000.0 0.37 0.3837 0.939 3628552 CBKinase1_018405 COC(=O)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M12 compound treatment 3780613.0 314000.0 0.26 4035279.0 657000.0 0.52 0.5578 0.9501 3628553 CBKinase1_018406 [O-][N+](=O)c1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M13 mock treatment 3886266.0 420000.0 0.35 3998354.0 620000.0 0.49 0.6 0.9866 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M14 mock treatment 4198608.0 732000.0 0.62 3621036.0 243000.0 0.19 0.5736 0.8864 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M15 compound treatment 4026109.0 560000.0 0.47 3649830.0 272000.0 0.22 0.487 0.9376 3628554 CBKinase1_018407 COc1ccccc1Nc2nc(N)nc(CN3CCCCCC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M16 compound treatment 4537755.0 1070000.0 0.9 3794279.0 416000.0 0.33 0.8736 0.9075 3628555 CBKinase1_018408 Cn1c(SCc2ccccc2C#N)nnc1c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M17 compound treatment 4292725.0 826000.0 0.7 3654482.0 277000.0 0.22 0.6486 0.8874 3628556 CBKinase1_018409 CCOc1ccc(cc1)N2C(=O)CC(SCc3nc4ccccc4[nH]3)C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M18 compound treatment 4780023.0 1310000.0 1.11 3537597.0 160000.0 0.13 0.8734 0.7832 3628557 CBKinase1_018410 O=C(Nc1ccccc1)c2ccc(CSc3nnc(c4ccncc4)n3c5ccccc5)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M19 compound treatment 5486533.0 2020000.0 1.7 3121012.0 -257000.0 -0.2 1.06 0.6177 1677807 CBKinase1_018411 O=C(NCCN1CCOCC1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M20 compound treatment 4650594.0 1180000.0 1.0 4112946.0 735000.0 0.59 1.1205 0.9677 3628558 CBKinase1_018412 CS(=O)(=O)N(CC(=O)Nc1ccc2OCCOc2c1)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M21 compound treatment 4793732.0 1330000.0 1.12 4282993.0 905000.0 0.72 1.3017 0.9774 3628559 CBKinase1_018413 COCCNc1ncnc2c3ccccc3oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M22 compound treatment 4463159.0 997000.0 0.84 3592378.0 214000.0 0.17 0.7153 0.8338 3628560 CBKinase1_018414 COc1ccc(cc1)n2nnnc2SCC(=O)Nc3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M23 compound treatment 4557293.0 1090000.0 0.92 3011288.0 -367000.0 -0.29 0.4439 0.4599 3628561 CBKinase1_018415 [O-][N+](=O)c1ccc(NC(=O)CSc2ncn(n2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 M24 compound treatment 3854707.0 388000.0 0.33 2284690.0 -1090000.0 -0.87 -0.3846 -0.4132 3628562 CBKinase1_018416 OCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N01 compound treatment 2913066.0 -553000.0 -0.47 2562336.0 -816000.0 -0.65 -0.7898 -0.9868 3628563 CBKinase1_018417 Nc1nnc(SCC(=O)NC2CCCCC2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N02 compound treatment 3001910.0 -465000.0 -0.39 2457268.0 -921000.0 -0.73 -0.796 -0.9568 3628564 CBKinase1_018418 CC(=O)c1cccc(NC(=S)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N03 compound treatment 3277261.0 -189000.0 -0.16 2836567.0 -541000.0 -0.43 -0.418 -0.9085 3628565 CBKinase1_018419 CCn1c(SCC(=O)c2ccc(F)cc2)nnc1c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N04 compound treatment 3628535.0 162000.0 0.14 2868959.0 -509000.0 -0.41 -0.1902 -0.4444 3628566 CBKinase1_018420 CC1CC2(CC(C)(OC2=O)C(=O)CSc3nnc([nH]3)c4ccccc4Cl)C(=O)O1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N05 compound treatment 3560080.0 93600.0 0.08 2944868.0 -433000.0 -0.35 -0.1883 -0.5317 3628567 CBKinase1_018421 COc1ccc(OC(C)C(=O)Nc2cc(C)c(Cl)cc2OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N06 compound treatment 3620122.0 154000.0 0.13 3256582.0 -121000.0 -0.1 0.0232 0.1436 3628568 CBKinase1_018422 COC(=O)c1cn(C(=O)C(C)Oc2ccc(OC)cc2)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N07 compound treatment 3851797.0 385000.0 0.32 3191019.0 -187000.0 -0.15 0.1244 0.3481 3628569 CBKinase1_018423 CC(=C)Cn1c(SCc2nc3ccccc3[nH]2)nc4sc5CCCc5c4c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N08 compound treatment 3999463.0 533000.0 0.45 3526859.0 149000.0 0.12 0.4018 0.8642 3628570 CBKinase1_018424 CCOc1ccc(NC(=O)CSc2nnc(c3cccs3)n2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N09 mock treatment 3901388.0 435000.0 0.37 3494326.0 116000.0 0.09 0.325 0.8589 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N10 mock treatment 3493126.0 26600.0 0.02 3255830.0 -122000.0 -0.1 -0.053 -0.5302 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N11 compound treatment 3758279.0 292000.0 0.25 3416911.0 39000.0 0.03 0.196 0.7901 3628571 CBKinase1_018425 CC(C)c1ccc(NC(=O)CSc2nnnn2c3ccc(cc3)C(=O)N)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N12 compound treatment 3934207.0 468000.0 0.39 3418518.0 40600.0 0.03 0.3018 0.7625 3628572 CBKinase1_018426 COc1cc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)cc(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N13 mock treatment 4031385.0 565000.0 0.48 3477711.0 99800.0 0.08 0.3931 0.8139 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N14 mock treatment 4099803.0 633000.0 0.53 3547761.0 170000.0 0.14 0.4734 0.8591 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N15 compound treatment 4449253.0 983000.0 0.83 3849105.0 471000.0 0.38 0.8517 0.9359 3628573 CBKinase1_018427 COc1ccccc1Nc2nc(N)nc(CSc3nc4ccccc4s3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N16 compound treatment 4164177.0 698000.0 0.59 4005794.0 628000.0 0.5 0.77 0.9967 3628574 CBKinase1_018428 [O-][N+](=O)c1cccc(c1)c2nnc(SCC(=O)NC3CCCCC3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N17 compound treatment 3814424.0 348000.0 0.29 3756988.0 379000.0 0.3 0.4211 0.9999 1986171 CBKinase1_018429 CN(CCO)S(=O)(=O)c1cc(ccc1C)c2nnc3c4ccccc4c(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N18 compound treatment 4467787.0 1000000.0 0.84 3768332.0 390000.0 0.31 0.8172 0.908 3628575 CBKinase1_018430 OC(=O)CCNc1ncnc2c3ccccc3oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N19 compound treatment 3560327.0 93800.0 0.08 3073691.0 -304000.0 -0.24 -0.1155 -0.4529 1324023 CBKinase1_018431 Cn1nnnc1SCC(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N20 compound treatment 4751076.0 1280000.0 1.08 3969263.0 591000.0 0.47 1.0994 0.9305 3628576 CBKinase1_018432 COC(=O)C1=C(C)Nc2ncnn2C1c3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N21 compound treatment 4184713.0 718000.0 0.61 3945263.0 567000.0 0.45 0.7481 0.9896 3628577 CBKinase1_018433 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc2cccc3cccnc23)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N22 compound treatment 3768844.0 302000.0 0.26 4154652.0 777000.0 0.62 0.6181 0.9231 3628578 CBKinase1_018434 O=C(CSc1nnc(CN2CCOCC2)n1c3ccccc3)N4CCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N23 compound treatment 4295062.0 829000.0 0.7 3702649.0 325000.0 0.26 0.6772 0.9087 3628579 CBKinase1_018435 Cn1c(CN2CCOCC2)nnc1SCC(=O)N3CCc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 N24 compound treatment 3929164.0 463000.0 0.39 2559336.0 -819000.0 -0.65 -0.1854 -0.2439 3628580 CBKinase1_018436 COc1ccc(OC(C)C(=O)Nc2cc(OC)cc(OC)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O01 compound treatment 1978568.0 -1490000.0 -1.26 3036172.0 -342000.0 -0.27 -1.0801 -0.841 3628581 CBKinase1_018437 CCOc1ccc(NC(=O)Cn2c(nc3sc4CCCCc4c3c2=O)c5ccc(OC)cc5)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O02 compound treatment 2460594.0 -1010000.0 -0.85 3818370.0 440000.0 0.35 -0.3518 -0.3831 3628582 CBKinase1_018438 Cn1c(CN2CCOCC2)nnc1SCC(=O)Nc3cc(ccc3Cl)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O03 compound treatment 2100861.0 -1370000.0 -1.15 3521950.0 144000.0 0.11 -0.7334 -0.6335 3628583 CBKinase1_018439 [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O04 compound treatment 2172997.0 -1290000.0 -1.09 3446509.0 68600.0 0.05 -0.7329 -0.6708 3628584 CBKinase1_018440 Cc1c(F)cccc1NC(=O)C2CC=CCC2C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O05 compound treatment 2331641.0 -1130000.0 -0.96 3746000.0 368000.0 0.29 -0.4695 -0.4689 3628585 CBKinase1_018441 CC(=O)Nc1ccccc1NC(=O)COc2ccc(cc2Br)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O06 compound treatment 2482670.0 -984000.0 -0.83 3803781.0 426000.0 0.34 -0.3468 -0.3868 3628586 CBKinase1_018442 Cc1ccc(NC(=O)C(=O)NCCc2c[nH]c3ccccc23)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O07 compound treatment 3018244.0 -448000.0 -0.38 3795205.0 417000.0 0.33 -0.0322 -0.064 3628587 CBKinase1_018443 COc1ccc(cc1)C(=O)Nc2ccc(cc2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O08 compound treatment 2998086.0 -468000.0 -0.4 3950443.0 572000.0 0.46 0.0433 0.0717 3628588 CBKinase1_018444 Cn1nnnc1SCC(=O)Nc2cccc(Cl)c2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O09 compound treatment 3228216.0 -238000.0 -0.2 3066190.0 -312000.0 -0.25 -0.3178 -0.9945 3628589 CBKinase1_018445 COC(=O)c1ccc(OC(=O)CS(=O)c2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O10 compound treatment 3205904.0 -261000.0 -0.22 3586175.0 208000.0 0.17 -0.0381 -0.1383 3628590 CBKinase1_018446 COc1ccc(OC(C)C(=O)NCC2CCCO2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O11 mock treatment 3649150.0 183000.0 0.15 3580659.0 203000.0 0.16 0.2232 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O12 mock treatment 4086985.0 620000.0 0.52 4155965.0 778000.0 0.62 0.8086 0.9964 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O13 compound treatment 4172215.0 706000.0 0.6 4037667.0 660000.0 0.53 0.7927 0.9981 3628591 CBKinase1_018447 [O-][N+](=O)c1ccc(NCCNC(=O)c2ccco2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O14 compound treatment 4067949.0 601000.0 0.51 4238747.0 861000.0 0.69 0.8439 0.989 3628592 CBKinase1_018448 CCOc1ccc2nc(NS(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-])sc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O15 compound treatment 3719242.0 253000.0 0.21 3488862.0 111000.0 0.09 0.2132 0.924 3628593 CBKinase1_018449 CCc1cc2c(=O)n(c(SCC(=O)Nc3ccc(cc3)[N+](=O)[O-])nc2s1)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O16 compound treatment 4798073.0 1330000.0 1.12 4248515.0 871000.0 0.69 1.2848 0.9732 3628594 CBKinase1_018450 Fc1ccc(NC(=O)CSc2nc3ccccc3c(=O)[nH]2)c(F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O17 compound treatment 4189233.0 723000.0 0.61 3697582.0 320000.0 0.25 0.6112 0.9251 3628595 CBKinase1_018451 Cc1ccc(cc1)c2nnc(N3CCN(CC3)C(=O)CSc4nc(C)cc(C)n4)c5ccccc25 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O18 compound treatment 4832432.0 1370000.0 1.15 4504205.0 1130000.0 0.9 1.4494 0.9924 3628596 CBKinase1_018452 COc1ccc(OC(C)C(=O)Nc2ccncc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O19 compound treatment 5609246.0 2140000.0 1.81 4869161.0 1490000.0 1.19 2.1185 0.9793 3628597 CBKinase1_018453 Nc1ccc2nc(SCC(=O)Nc3ccc(Oc4ccccc4)cc3)sc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O20 compound treatment 5224356.0 1760000.0 1.48 4971047.0 1590000.0 1.27 1.9463 0.997 3628598 CBKinase1_018454 Clc1ccc(cc1)C(=O)CSc2nnc(c3cccs3)n2c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O21 compound treatment 6012173.0 2550000.0 2.15 5343236.0 1970000.0 1.57 2.626 0.988 3628599 CBKinase1_018455 COc1cc(cc(Br)c1OCC(=O)O)c2nc3sc4CCCCc4c3c(=O)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O22 compound treatment 5061741.0 1600000.0 1.35 4747772.0 1370000.0 1.09 1.7235 0.9946 3628600 CBKinase1_018456 Cc1cc(CN2CCN(CCC#N)CC2)c(O)c(c1)C3(C)CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O23 compound treatment 4794635.0 1330000.0 1.12 4321335.0 943000.0 0.75 1.3238 0.9812 3628601 CBKinase1_018457 CC(C)C(=O)Nc1ccc(cc1)C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 O24 compound treatment 3687818.0 221000.0 0.19 3611227.0 233000.0 0.19 0.2635 1.0 3628602 CBKinase1_018458 COc1ccc(NC(=O)CSc2nnc(N)n2c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P01 compound treatment 2737643.0 -729000.0 -0.61 2624386.0 -754000.0 -0.6 -0.8594 -0.9999 3628603 CBKinase1_018459 Brc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P02 compound treatment 2766828.0 -700000.0 -0.59 3088821.0 -289000.0 -0.23 -0.5803 -0.9159 3628604 CBKinase1_018460 COc1ccc(Cl)cc1NC(=O)CSc2nnnn2c3ccc(cc3)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P03 compound treatment 3002817.0 -464000.0 -0.39 3153853.0 -224000.0 -0.18 -0.4029 -0.9369 3628605 CBKinase1_018461 CN(Cc1nc(no1)c2ccncc2)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P04 compound treatment 3045987.0 -421000.0 -0.35 2737439.0 -641000.0 -0.51 -0.6118 -0.9842 3628606 CBKinase1_018462 Cc1ccnc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P05 compound treatment 3407658.0 -58900.0 -0.05 2953615.0 -424000.0 -0.34 -0.2743 -0.8023 3212453 CBKinase1_018463 O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc3ccccc3N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P06 compound treatment 3343627.0 -123000.0 -0.1 3034833.0 -343000.0 -0.27 -0.2667 -0.9118 3628607 CBKinase1_018464 Nc1nnc(SCC(=O)N2CCc3ccccc23)n1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P07 compound treatment 2921111.0 -545000.0 -0.46 3289204.0 -88700.0 -0.07 -0.3753 -0.8063 3628608 CBKinase1_018465 O=C(CSc1nnc(c2cccs2)n1c3ccccc3)N4CCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P08 compound treatment 3215407.0 -251000.0 -0.21 3347082.0 -30900.0 -0.02 -0.1672 -0.784 3628609 CBKinase1_018466 Cc1cccc(c1C)n2c(SCC(=O)c3ccccc3)nnc2c4ccncc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P09 compound treatment 3268125.0 -198000.0 -0.17 2826247.0 -552000.0 -0.44 -0.4293 -0.9124 3628610 CBKinase1_018467 Cc1sc2nc(C)nc(NCC3CCCO3)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P10 compound treatment 3322048.0 -144000.0 -0.12 2895827.0 -482000.0 -0.38 -0.3579 -0.8878 3628611 CBKinase1_018468 CCCn1nnc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P11 mock treatment 3241226.0 -225000.0 -0.19 3507753.0 130000.0 0.1 -0.0612 -0.2829 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P12 mock treatment 3300825.0 -166000.0 -0.14 3247623.0 -130000.0 -0.1 -0.1723 -0.9893 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P13 compound treatment 3615900.0 149000.0 0.13 2955222.0 -423000.0 -0.34 -0.1492 -0.4146 3628612 CBKinase1_018469 CS(=O)(=O)N(CC(=O)NC1CCCCC1)c2ccc3CCc4cccc2c43 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P14 compound treatment 3724728.0 258000.0 0.22 2962315.0 -416000.0 -0.33 -0.0802 -0.2024 3628613 CBKinase1_018470 Cn1c(Cc2cccs2)nnc1SCC(=O)N3CCCc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P15 compound treatment 3591511.0 125000.0 0.11 3761770.0 384000.0 0.31 0.2909 0.8989 3628614 CBKinase1_018471 CN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P16 compound treatment 3889316.0 423000.0 0.36 3877380.0 499000.0 0.4 0.5336 0.9985 3628615 CBKinase1_018472 COc1ccc(NC(=O)COc2ccc(cc2Br)C(C)(C)C)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P17 compound treatment 3327290.0 -139000.0 -0.12 3087452.0 -290000.0 -0.23 -0.2468 -0.9505 3628616 CBKinase1_018473 COc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3OC)nc4sc5CCCCc5c4c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P18 compound treatment 3775118.0 309000.0 0.26 3721325.0 343000.0 0.27 0.3776 0.9997 1418339 CBKinase1_018474 COc1ccc(OC)c(NS(=O)(=O)c2cccc3cccnc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P19 compound treatment 4388587.0 922000.0 0.78 4459933.0 1080000.0 0.86 1.1598 0.9987 3628617 CBKinase1_018475 COc1ccc(OC(C)C(=O)Nc2cc3oc4ccccc4c3cc2OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P20 compound treatment 3989416.0 523000.0 0.44 3818503.0 441000.0 0.35 0.5602 0.9936 3628618 CBKinase1_018476 COc1ccc(Cl)cc1NC(=O)CSc2nc3ccc(NC(=O)c4ccc(C)cc4)cc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P21 compound treatment 4259895.0 793000.0 0.67 3842295.0 464000.0 0.37 0.7349 0.961 3628619 CBKinase1_018477 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CCc2ccc(C)o2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P22 compound treatment 4254278.0 788000.0 0.66 3679241.0 301000.0 0.24 0.6397 0.9054 3628620 CBKinase1_018478 COc1ccccc1Nc2nc(N)nc(CSc3ncccn3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P23 compound treatment 4405773.0 939000.0 0.79 3922170.0 544000.0 0.43 0.8669 0.9598 3628621 CBKinase1_018479 CCC(Sc1ccccn1)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2381 P24 compound treatment 3517674.0 51100.0 0.04 3154703.0 -223000.0 -0.18 -0.0953 -0.5206 3628622 CBKinase1_018480 COc1cc(ccc1NC(=O)CS(=O)(=O)Cc2ccccc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A01 compound treatment 1508297.0 -1470000.0 -1.24 2441982.0 -558000.0 -0.44 -1.192 -0.9042 3027327 CBKinase1_018481 CN(C)c1nc(OCCNS(=O)(=O)c2ccc(C)cc2)nc(n1)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A02 compound treatment 2955841.0 -23600.0 -0.02 2761918.0 -238000.0 -0.19 -0.1483 -0.7771 3628623 CBKinase1_018482 CC(=O)Nc1ccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A03 compound treatment 2149231.0 -830000.0 -0.7 2671892.0 -328000.0 -0.26 -0.6801 -0.9098 3628624 CBKinase1_018483 COc1ccccc1Nc2nc(N)nc(CSc3nccn3C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A04 compound treatment 3814421.0 835000.0 0.7 3732048.0 732000.0 0.58 0.9106 0.9956 3628625 CBKinase1_018484 Brc1ccc(CNc2nc3ccccc3n2CCN4CCOCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A05 compound treatment 2946210.0 -33300.0 -0.03 2622908.0 -377000.0 -0.3 -0.2324 -0.7698 3628626 CBKinase1_018485 COc1ccc(OC(C)C(=O)Nc2cc(C)ccc2OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A06 compound treatment 2160314.0 -819000.0 -0.69 2252930.0 -747000.0 -0.6 -0.9096 -0.9973 3628627 CBKinase1_018486 CC(NS(=O)(=O)c1cc(ccc1C)c2nnc3c4ccccc4c(C)nn23)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A07 compound treatment 2288439.0 -691000.0 -0.58 2447655.0 -552000.0 -0.44 -0.7235 -0.9904 3628628 CBKinase1_018487 OC(=O)c1ccc(NC(=O)Cn2c(=O)oc3ccccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A08 compound treatment 2921694.0 -57800.0 -0.05 3027673.0 27700.0 0.02 -0.0189 -0.3528 3628629 CBKinase1_018488 Fc1cc(F)c(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A09 compound treatment 3046780.0 67300.0 0.06 2659355.0 -341000.0 -0.27 -0.1518 -0.5474 3628630 CBKinase1_018489 [O-][N+](=O)c1cccc(c1)c2nn(CC(=O)NCC3CCCO3)c(=O)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A10 compound treatment 2870426.0 -109000.0 -0.09 2663789.0 -336000.0 -0.27 -0.2545 -0.8984 3628631 CBKinase1_018490 CCOC(=O)c1c(NC(=S)Nc2nc(C)cc(C)n2)sc(C)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A11 compound treatment 2831094.0 -148000.0 -0.13 2435395.0 -565000.0 -0.45 -0.4067 -0.8707 3628632 CBKinase1_018491 OC(=O)c1c(NC(=O)Cn2c(=O)oc3ccccc23)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A12 compound treatment 2208767.0 -771000.0 -0.65 2007953.0 -992000.0 -0.79 -1.0188 -0.9953 3628633 CBKinase1_018492 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A13 mock treatment 2877916.0 -102000.0 -0.09 2758643.0 -241000.0 -0.19 -0.1966 -0.9336 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A14 mock treatment 2924840.0 -54600.0 -0.05 2618495.0 -382000.0 -0.3 -0.2476 -0.8051 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A15 compound treatment 3231275.0 252000.0 0.21 2619307.0 -381000.0 -0.3 -0.0644 -0.1738 3628634 CBKinase1_018493 Clc1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A16 compound treatment 3150546.0 171000.0 0.14 2928068.0 -72000.0 -0.06 0.0615 0.396 3628635 CBKinase1_018494 Cc1ccccc1N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A17 compound treatment 2870729.0 -109000.0 -0.09 2719612.0 -280000.0 -0.22 -0.2229 -0.9226 3628636 CBKinase1_018495 COc1ccc(Nc2nc(N)nc(COc3ccc(OC)cc3)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A18 compound treatment 2829696.0 -150000.0 -0.13 2590001.0 -410000.0 -0.33 -0.3204 -0.9145 3628637 CBKinase1_018496 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(C)s3)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A19 compound treatment 2059945.0 -920000.0 -0.78 2049649.0 -950000.0 -0.76 -1.0841 -0.9999 3628638 CBKinase1_018497 COc1ccc(OCC(=O)Nc2cccc(c2)c3nnc4c5ccccc5c(C)nn34)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A20 compound treatment 2865058.0 -114000.0 -0.1 3329783.0 330000.0 0.26 0.1176 0.4201 3628639 CBKinase1_018498 CSc1ccccc1NC(=O)CN(c2cc(Cl)ccc2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A21 compound treatment 3002186.0 22700.0 0.02 2988103.0 -11900.0 -0.01 0.0068 0.3196 3628640 CBKinase1_018499 OC(=O)c1cccc(c1)n2nnnc2SCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A22 compound treatment 3051824.0 72400.0 0.06 3241977.0 242000.0 0.19 0.1795 0.8875 3628641 CBKinase1_018500 CC(=O)c1cccc(NC(=O)Nc2nn(Cc3c(F)cccc3Cl)cc2Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A23 compound treatment 2806599.0 -173000.0 -0.15 2887160.0 -113000.0 -0.09 -0.1667 -0.9731 3628642 CBKinase1_018501 CN(CC(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 A24 compound treatment 2480221.0 -499000.0 -0.42 2854676.0 -145000.0 -0.12 -0.3797 -0.8693 3628643 CBKinase1_018502 COC(=O)c1cc(sc1NC(=S)Nc2cccc(NC(=O)C)c2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B01 compound treatment 2199179.0 -780000.0 -0.66 2966855.0 -33200.0 -0.03 -0.4841 -0.7349 3628644 CBKinase1_018503 COc1ccc(OC)c(NC(=O)Nc2cccc(Cn3cccn3)c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B02 compound treatment 2676513.0 -303000.0 -0.26 3579296.0 579000.0 0.46 0.1458 0.2763 3628645 CBKinase1_018504 O=C(CC1NCCNC1=O)Nc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B03 compound treatment 2951253.0 -28200.0 -0.02 3572658.0 573000.0 0.46 0.3059 0.6693 3628646 CBKinase1_018505 Fc1ccc(NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B04 compound treatment 3836924.0 857000.0 0.72 3000698.0 680.0 0.0 0.5118 0.7076 3628647 CBKinase1_018506 COc1ccc(OC)c(c1)N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B05 compound treatment 2652353.0 -327000.0 -0.28 2953995.0 -46000.0 -0.04 -0.221 -0.7941 3628648 CBKinase1_018507 COc1ccc(C)cc1NC(=O)c2ccccc2N(C)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B06 compound treatment 2905202.0 -74300.0 -0.06 4771015.0 1770000.0 1.41 0.9538 0.6751 3628649 CBKinase1_018508 CSc1ccccc1NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B07 compound treatment 2577818.0 -402000.0 -0.34 4056545.0 1060000.0 0.84 0.3559 0.3921 3628650 CBKinase1_018509 Cc1ccc(cc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Cl)cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B08 compound treatment 2887429.0 -92000.0 -0.08 3321039.0 321000.0 0.26 0.126 0.4713 3628651 CBKinase1_018510 CSc1ccccc1NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B09 compound treatment 2949477.0 -30000.0 -0.03 3037848.0 37800.0 0.03 0.0034 0.0873 3628652 CBKinase1_018511 CC(=O)c1ccc(NC(=O)CSc2nc(C)c(C)c(O)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B10 compound treatment 2873067.0 -106000.0 -0.09 3289695.0 290000.0 0.23 0.0998 0.4029 3628653 CBKinase1_018512 CC(C)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B11 compound treatment 3008692.0 29200.0 0.02 3354220.0 354000.0 0.28 0.2171 0.7659 3628654 CBKinase1_018513 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2ccc(I)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B12 compound treatment 3106644.0 127000.0 0.11 3879739.0 880000.0 0.7 0.5717 0.8059 3628655 CBKinase1_018514 Nc1nncn1C(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B13 mock treatment 3305934.0 326000.0 0.28 3602867.0 603000.0 0.48 0.5345 0.9651 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B14 mock treatment 3162130.0 183000.0 0.15 3767104.0 767000.0 0.61 0.5413 0.8585 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B15 compound treatment 3502473.0 523000.0 0.44 3589327.0 589000.0 0.47 0.6441 0.9995 3628656 CBKinase1_018515 O=C(CC1Sc2ncnn2C1=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B16 compound treatment 2834395.0 -145000.0 -0.12 3109935.0 110000.0 0.09 -0.0246 -0.1633 3628657 CBKinase1_018516 COc1ccccc1OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B17 compound treatment 2995738.0 16300.0 0.01 3501453.0 501000.0 0.4 0.2923 0.731 1259401 CBKinase1_018517 COc1ccc(C)cc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B18 compound treatment 3268315.0 289000.0 0.24 3716509.0 716000.0 0.57 0.5761 0.9279 3628658 CBKinase1_018518 CS(=O)(=O)CCC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)N3CCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B19 compound treatment 3246363.0 267000.0 0.23 3499035.0 499000.0 0.4 0.4404 0.9637 3628659 CBKinase1_018519 CCC(=O)Nc1nonc1c2nc3ccccc3n2Cc4cc(OC)ccc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B20 compound treatment 3358395.0 379000.0 0.32 3867828.0 868000.0 0.69 0.7151 0.9385 3628660 CBKinase1_018520 CCC(=O)Nc1ccccc1c2nnc(SCc3ccccc3)nc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B21 compound treatment 3337227.0 358000.0 0.3 3654568.0 655000.0 0.52 0.5823 0.9661 3628661 CBKinase1_018521 CN(CC(=O)Nc1ccccc1Sc2ccccc2)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B22 compound treatment 3425213.0 446000.0 0.38 3752232.0 752000.0 0.6 0.6898 0.9747 3628662 CBKinase1_018522 OC(=O)CCCC(=O)Nc1ccc(Br)cc1C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B23 compound treatment 3124578.0 145000.0 0.12 3368751.0 369000.0 0.29 0.2944 0.9246 3628663 CBKinase1_018523 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)c(Cl)c1)c2cc(Cl)ccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 B24 compound treatment 2774783.0 -205000.0 -0.17 3115298.0 115000.0 0.09 -0.0571 -0.292 3628664 CBKinase1_018524 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3cccc4CCCCc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C01 compound treatment 2581318.0 -398000.0 -0.34 1801749.0 -1200000.0 -0.96 -0.9128 -0.9016 3628665 CBKinase1_018525 CCc1ccc2n(CC(=O)OC)c3nc4ccccc4nc3c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C02 compound treatment 2430118.0 -549000.0 -0.46 2459242.0 -541000.0 -0.43 -0.6324 -0.9993 3628666 CBKinase1_018526 CN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(Cc3ccco3)C1=S 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C03 compound treatment 3392707.0 413000.0 0.35 3509376.0 509000.0 0.41 0.5335 0.9971 3628667 CBKinase1_018527 CC(=O)Nc1ccccc1c2nc3ccccc3nc2OCC(=O)c4ccc5ccccc5c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C04 compound treatment 2857796.0 -122000.0 -0.1 2578974.0 -421000.0 -0.34 -0.3099 -0.883 3628668 CBKinase1_018528 Clc1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C05 compound treatment 2747855.0 -232000.0 -0.2 2792443.0 -208000.0 -0.17 -0.2551 -0.9966 3628669 CBKinase1_018529 Cc1ccc(NC(=O)CSc2nnnn2c3cccc(c3)C(=O)O)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C06 compound treatment 2771829.0 -208000.0 -0.18 2229966.0 -770000.0 -0.61 -0.5578 -0.874 3628670 CBKinase1_018530 COc1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1S(=O)(=O)N5CCCCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C07 compound treatment 2509434.0 -470000.0 -0.4 2552346.0 -448000.0 -0.36 -0.5327 -0.9986 3628671 CBKinase1_018531 O=C(NCc1ccccc1)C2CC(=O)NC(=N2)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C08 compound treatment 2567458.0 -412000.0 -0.35 2699572.0 -300000.0 -0.24 -0.4151 -0.9835 3628672 CBKinase1_018532 COc1ccc(Cl)cc1NC(=S)NCc2cc(C)n(C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C09 compound treatment 2806993.0 -172000.0 -0.15 2855985.0 -144000.0 -0.11 -0.184 -0.9931 3628673 CBKinase1_018533 CC1(C)CC2(CC(C)(OC2=O)C(=O)CSc3nnc([nH]3)c4ccccc4Br)C(=O)O1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C10 compound treatment 2796798.0 -183000.0 -0.15 2792638.0 -207000.0 -0.17 -0.2258 -0.9994 1803924 CBKinase1_018534 CC(Sc1nc(C)cc(C)n1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C11 mock treatment 2782653.0 -197000.0 -0.17 3028578.0 28600.0 0.02 -0.1013 -0.6045 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C12 mock treatment 2837260.0 -142000.0 -0.12 2900088.0 -99900.0 -0.08 -0.1411 -0.9802 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C13 compound treatment 2764509.0 -215000.0 -0.18 2973807.0 -26200.0 -0.02 -0.143 -0.7834 3119010 CBKinase1_018535 COc1ccc(cc1)C(=O)Nc2nonc2NC(=O)c3ccc(OC)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C14 compound treatment 3021480.0 42000.0 0.04 2798851.0 -201000.0 -0.16 -0.0883 -0.5378 3628674 CBKinase1_018536 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4ccccc4Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C15 mock treatment 3101451.0 122000.0 0.1 2986566.0 -13500.0 -0.01 0.0652 0.63 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C16 mock treatment 2789474.0 -190000.0 -0.16 2826637.0 -173000.0 -0.14 -0.211 -0.9973 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C17 compound treatment 3210174.0 231000.0 0.19 2930105.0 -69900.0 -0.06 0.0982 0.4851 3628675 CBKinase1_018537 CCCn1c(NCCCO)nc2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C18 compound treatment 3071056.0 91600.0 0.08 2901678.0 -98300.0 -0.08 -8.0E-4 -0.0072 3628676 CBKinase1_018538 COc1ccc(CN2C(=O)C(O)(CC(=O)c3c(C)coc3C)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C19 compound treatment 3291029.0 312000.0 0.26 3139299.0 139000.0 0.11 0.2643 0.9265 3628677 CBKinase1_018539 CC(C)c1ccc(C)c(OCC(O)Cn2cnc3ccccc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C20 compound treatment 4229628.0 1250000.0 1.05 2912364.0 -87700.0 -0.07 0.6962 0.6588 3628678 CBKinase1_018540 Cc1c(NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C21 compound treatment 3114424.0 135000.0 0.11 2726082.0 -274000.0 -0.22 -0.0739 -0.3001 3628679 CBKinase1_018541 CSc1cccc(NC(=O)CSc2nnc(N)s2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C22 compound treatment 3132423.0 153000.0 0.13 2792804.0 -207000.0 -0.17 -0.0256 -0.1219 3628680 CBKinase1_018542 COc1ccc(cc1OC)c2cc(C(=O)N3CCCC3C(=O)O)c(C)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C23 compound treatment 2914669.0 -64800.0 -0.05 2596122.0 -404000.0 -0.32 -0.2663 -0.8155 3628681 CBKinase1_018543 Cc1ccc(cc1)c2noc(CSc3nnc(c4cccs4)n3C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 C24 compound treatment 2595539.0 -384000.0 -0.32 2537822.0 -462000.0 -0.37 -0.4895 -0.9979 3628682 CBKinase1_018544 COC(=O)c1cc(NC(=O)Cc2ccccc2[N+](=O)[O-])ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D01 compound treatment 2207011.0 -772000.0 -0.65 2297248.0 -703000.0 -0.56 -0.8568 -0.9972 3628683 CBKinase1_018545 Cc1ccccc1NC(=O)CC(N2CCOCC2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D02 compound treatment 2622022.0 -357000.0 -0.3 2578740.0 -421000.0 -0.34 -0.4506 -0.9986 3628684 CBKinase1_018546 CN(CC(=O)Nc1ccccc1F)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D03 compound treatment 2662018.0 -317000.0 -0.27 2702079.0 -298000.0 -0.24 -0.3573 -0.9982 3628685 CBKinase1_018547 CN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D04 compound treatment 2911468.0 -68000.0 -0.06 2922797.0 -77200.0 -0.06 -0.0841 -0.9994 3628686 CBKinase1_018548 COC(C(=O)Nc1ccccc1C(=O)N2CCOCC2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D05 compound treatment 3538073.0 559000.0 0.47 3349295.0 349000.0 0.28 0.53 0.9685 3628687 CBKinase1_018549 COc1ccc(OC)c(c1)N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D06 compound treatment 3026660.0 47200.0 0.04 3118498.0 118000.0 0.09 0.0949 0.9263 3628688 CBKinase1_018550 Fc1ccccc1NC(=O)CSc2nnc([nH]2)c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D07 compound treatment 2868024.0 -111000.0 -0.09 2887314.0 -113000.0 -0.09 -0.13 -0.9997 3628689 CBKinase1_018551 COc1ccc(NC(=S)N2CCN(Cc3c(C)nn(C)c3C)CC2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D08 compound treatment 3115537.0 136000.0 0.11 3155584.0 156000.0 0.12 0.1688 0.9993 3628690 CBKinase1_018552 Cc1ccc(cc1)n2c(N)cc(=O)nc2SCC(=O)Nc3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D09 compound treatment 2879536.0 -99900.0 -0.08 3239732.0 240000.0 0.19 0.0755 0.3615 3628691 CBKinase1_018553 Cc1ccc(cc1)S(=O)(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D10 compound treatment 3203322.0 224000.0 0.19 3386762.0 387000.0 0.31 0.3515 0.9723 3628692 CBKinase1_018554 CN(Cc1nc(no1)c2ccc(Br)cc2)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D11 mock treatment 3130733.0 151000.0 0.13 3502749.0 503000.0 0.4 0.3736 0.8883 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D12 mock treatment 3317289.0 338000.0 0.28 3568179.0 568000.0 0.45 0.5217 0.9751 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D13 compound treatment 3212498.0 233000.0 0.2 3573168.0 573000.0 0.46 0.462 0.929 3628693 CBKinase1_018555 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3ccc(Cl)c(Cl)c3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D14 compound treatment 3355060.0 376000.0 0.32 3111109.0 111000.0 0.09 0.2866 0.8713 3628694 CBKinase1_018556 Clc1cc(Cl)c(OCC(=O)NCc2ccco2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D15 mock treatment 3015824.0 36400.0 0.03 3254571.0 255000.0 0.2 0.1652 0.8049 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D16 mock treatment 3044824.0 65400.0 0.06 3340828.0 341000.0 0.27 0.2311 0.8336 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D17 compound treatment 3041431.0 62000.0 0.05 3489552.0 490000.0 0.39 0.3129 0.7947 3628695 CBKinase1_018557 COc1ccc(NC(=O)CC(N2CCOCC2)C(=O)O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D18 compound treatment 3398652.0 419000.0 0.35 3410240.0 410000.0 0.33 0.4812 0.9992 3628696 CBKinase1_018558 CCn1c2ccccc2c3cc(NC(=O)CCCN4C(=O)c5ccccc5C4=O)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D19 compound treatment 3761117.0 782000.0 0.66 3698457.0 698000.0 0.56 0.8598 0.9965 3628697 CBKinase1_018559 [O-][N+](=O)c1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D20 compound treatment 3868811.0 889000.0 0.75 3405050.0 405000.0 0.32 0.7587 0.929 3628698 CBKinase1_018560 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)C(=O)Nc3ccccc3C(=O)N4CCN(CC4)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D21 compound treatment 3100581.0 121000.0 0.1 3116292.0 116000.0 0.09 0.1378 0.9988 3628699 CBKinase1_018561 COc1c(C)cc(c(C)c1C)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D22 compound treatment 3024000.0 44500.0 0.04 3244525.0 245000.0 0.19 0.1644 0.8282 3628700 CBKinase1_018562 CC(=O)Nc1ccccc1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D23 compound treatment 3097667.0 118000.0 0.1 3119224.0 119000.0 0.1 0.1377 0.9997 3628701 CBKinase1_018563 Cc1nnc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 D24 compound treatment 2663274.0 -316000.0 -0.27 2730535.0 -269000.0 -0.21 -0.3405 -0.9942 3628702 CBKinase1_018564 Clc1cc(Cl)c(OCC(=O)NCCN2CCOCC2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E01 mock treatment 1096010.0 -1880000.0 -1.59 1148469.0 -1850000.0 -1.48 -2.1669 -0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E02 mock treatment 1321756.0 -1660000.0 -1.4 1019096.0 -1980000.0 -1.58 -2.1052 -0.9982 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E03 compound treatment 1522397.0 -1460000.0 -1.23 1069016.0 -1930000.0 -1.54 -1.9574 -0.9938 3628703 CBKinase1_018565 CCn1c(SCC(=O)Nc2ccc(C)cc2)nc3ccc(I)cc3c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E04 compound treatment 1705954.0 -1270000.0 -1.07 1421255.0 -1580000.0 -1.26 -1.6494 -0.9969 3628704 CBKinase1_018566 CN(CC(=O)Nc1ccccc1NC(=O)C)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E05 compound treatment 1778021.0 -1200000.0 -1.01 1384071.0 -1620000.0 -1.29 -1.6273 -0.993 3628705 CBKinase1_018567 CN(CC(=O)Nc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E06 compound treatment 3026482.0 47000.0 0.04 1687451.0 -1310000.0 -1.05 -0.7117 -0.6798 3628706 CBKinase1_018568 FC(F)(F)c1ccccc1NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E07 compound treatment 1825387.0 -1150000.0 -0.97 1363878.0 -1640000.0 -1.3 -1.6105 -0.9896 3628707 CBKinase1_018569 Cc1cc(nc(SCC(=O)Nc2ccccc2C#N)n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E08 compound treatment 1899895.0 -1080000.0 -0.91 1757487.0 -1240000.0 -0.99 -1.3442 -0.9991 3628708 CBKinase1_018570 Fc1ccccc1c2nnn(CC(=O)NCc3ccco3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E09 mock treatment 2168498.0 -811000.0 -0.68 2083499.0 -917000.0 -0.73 -1.0002 -0.9995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E10 mock treatment 2167270.0 -812000.0 -0.69 1857672.0 -1140000.0 -0.91 -1.1282 -0.9902 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E11 compound treatment 2319900.0 -660000.0 -0.56 2358435.0 -642000.0 -0.51 -0.755 -0.9991 3628709 CBKinase1_018571 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E12 compound treatment 2460895.0 -519000.0 -0.44 2189739.0 -810000.0 -0.65 -0.766 -0.982 3628710 CBKinase1_018572 CNc1nc(SC(C)C(=O)OC)nc(n1)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E13 compound treatment 2401986.0 -577000.0 -0.49 2195419.0 -805000.0 -0.64 -0.7979 -0.9908 3628711 CBKinase1_018573 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc2ccc(Cl)cc2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E14 compound treatment 2349244.0 -630000.0 -0.53 2376074.0 -624000.0 -0.5 -0.7275 -0.9994 3027249 CBKinase1_018574 O=C(CC1OCCN(Cc2ccccc2)C1=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E15 compound treatment 2406954.0 -573000.0 -0.48 2175562.0 -824000.0 -0.66 -0.8061 -0.9885 3628712 CBKinase1_018575 [O-][N+](=O)c1ccccc1S(=O)CC(=O)Oc2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E16 compound treatment 2438033.0 -541000.0 -0.46 2139052.0 -861000.0 -0.69 -0.8082 -0.9804 3628713 CBKinase1_018576 O=S(=O)(N1CCOCC1)c2cccc(NC(=S)NCc3ccco3)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E17 mock treatment 2480840.0 -499000.0 -0.42 2193974.0 -806000.0 -0.64 -0.7517 -0.9789 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E18 mock treatment 2584390.0 -395000.0 -0.33 2141323.0 -859000.0 -0.68 -0.7196 -0.9453 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E19 compound treatment 3240488.0 261000.0 0.22 2113498.0 -887000.0 -0.71 -0.344 -0.4647 3628714 CBKinase1_018577 O=C(CS(=O)(=O)Cc1ccccc1)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E20 compound treatment 2534980.0 -444000.0 -0.37 2278388.0 -722000.0 -0.58 -0.6718 -0.9785 3628715 CBKinase1_018578 O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc3ccccc3C(=O)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E21 compound treatment 2320032.0 -659000.0 -0.56 1939471.0 -1060000.0 -0.85 -0.991 -0.9794 3628716 CBKinase1_018579 CN(CC(=O)Nc1ccc(cc1)C(=O)C)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E22 compound treatment 2826606.0 -153000.0 -0.13 2339535.0 -660000.0 -0.53 -0.4634 -0.855 3628717 CBKinase1_018580 COc1cc(ccc1NC(=S)NCCn2cc(Br)cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E23 compound treatment 2695464.0 -284000.0 -0.24 2225110.0 -775000.0 -0.62 -0.6061 -0.915 3628718 CBKinase1_018581 O=C(CSc1nc2ccccc2s1)Nc3ccccc3N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 E24 compound treatment 2304438.0 -675000.0 -0.57 1905257.0 -1090000.0 -0.87 -1.0196 -0.9786 3628719 CBKinase1_018582 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(cc3)N4CCOCC4)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F01 mock treatment 1293336.0 -1690000.0 -1.42 818801.0 -2180000.0 -1.74 -2.235 -0.995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F02 mock treatment 2189483.0 -790000.0 -0.67 1432668.0 -1570000.0 -1.25 -1.3545 -0.9567 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F03 compound treatment 1398856.0 -1580000.0 -1.33 1316338.0 -1680000.0 -1.34 -1.8917 -1.0 3628720 CBKinase1_018583 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3ccccc3Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F04 compound treatment 1564362.0 -1420000.0 -1.19 1931949.0 -1070000.0 -0.85 -1.446 -0.9863 3628721 CBKinase1_018584 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2ccccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F05 compound treatment 1934393.0 -1050000.0 -0.88 1299820.0 -1700000.0 -1.36 -1.5815 -0.9783 3628722 CBKinase1_018585 Cc1sc(NC(=O)COc2ccc(cc2)c3ccccc3)c(C(=O)N)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F06 compound treatment 2643695.0 -336000.0 -0.28 2556674.0 -443000.0 -0.35 -0.4501 -0.994 1985047 CBKinase1_018586 COc1ccc(C(=O)CCC(=O)Nc2cccnc2)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F07 compound treatment 1799941.0 -1180000.0 -0.99 1425280.0 -1570000.0 -1.26 -1.591 -0.9934 3628723 CBKinase1_018587 CN1CCN(CC1)C(CC(=O)Nc2cccc(O)c2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F08 compound treatment 2008050.0 -971000.0 -0.82 1780054.0 -1220000.0 -0.97 -1.267 -0.9964 3628724 CBKinase1_018588 COc1ccc(Nc2nc(N)nc(CSc3nccc(C)n3)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F09 mock treatment 2111824.0 -868000.0 -0.73 1749778.0 -1250000.0 -1.0 -1.2221 -0.9885 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F10 mock treatment 2170190.0 -809000.0 -0.68 1880919.0 -1120000.0 -0.89 -1.1134 -0.9913 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F11 compound treatment 2268038.0 -711000.0 -0.6 2156293.0 -844000.0 -0.67 -0.8998 -0.9984 3628725 CBKinase1_018589 CN(C)C(CC(=O)Nc1cccc(Cl)c1Cl)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F12 compound treatment 2264047.0 -715000.0 -0.6 2197239.0 -803000.0 -0.64 -0.8791 -0.9996 3628726 CBKinase1_018590 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3ccccc3C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F13 compound treatment 2295503.0 -684000.0 -0.58 2068581.0 -931000.0 -0.74 -0.9329 -0.9922 3628727 CBKinase1_018591 COC(=O)c1ccccc1NC(=O)C2CCN(CC2)S(=O)(=O)c3cc(OC)ccc3OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F14 compound treatment 2303591.0 -676000.0 -0.57 1966500.0 -1030000.0 -0.82 -0.9856 -0.9838 3628728 CBKinase1_018592 [O-][N+](=O)c1cccc(c1)c2noc(CCCN3C(=O)c4ccccc4C3=O)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F15 compound treatment 2246243.0 -733000.0 -0.62 2027287.0 -973000.0 -0.78 -0.9856 -0.9937 3628729 CBKinase1_018593 CCc1cc(C(=O)OC)c(NC(=S)Nc2ccc(OC)cc2[N+](=O)[O-])s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F16 compound treatment 2093907.0 -886000.0 -0.75 1927615.0 -1070000.0 -0.85 -1.1326 -0.9977 3628730 CBKinase1_018594 COc1ccc(cc1S(=O)(=O)Nc2cccnc2)C(=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F17 mock treatment 2189594.0 -790000.0 -0.67 2126799.0 -873000.0 -0.7 -0.9633 -0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F18 mock treatment 2995631.0 16200.0 0.01 1987785.0 -1010000.0 -0.81 -0.5608 -0.6951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F19 compound treatment 2106900.0 -873000.0 -0.74 3008086.0 8070.0 0.01 -0.5159 -0.7009 3628731 CBKinase1_018595 COc1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Sc3nc[nH]n3)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F20 compound treatment 2411226.0 -568000.0 -0.48 2272205.0 -728000.0 -0.58 -0.7491 -0.9955 3628732 CBKinase1_018596 Oc1ccc(Cl)cc1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F21 compound treatment 2451553.0 -528000.0 -0.45 2229167.0 -771000.0 -0.61 -0.7493 -0.9875 3628733 CBKinase1_018597 COc1ccc(NC(=O)Nc2nn(Cc3ccc(Cl)cc3Cl)cc2Br)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F22 compound treatment 2099692.0 -880000.0 -0.74 2076009.0 -924000.0 -0.74 -1.0455 -1.0 3628734 CBKinase1_018598 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F23 compound treatment 2263998.0 -715000.0 -0.6 2340382.0 -660000.0 -0.53 -0.7985 -0.9976 3628735 CBKinase1_018599 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCCO 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 F24 compound treatment 2115658.0 -864000.0 -0.73 1845051.0 -1150000.0 -0.92 -1.1661 -0.9933 3628736 CBKinase1_018600 FC(F)(F)c1cc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G01 compound treatment 2526730.0 -453000.0 -0.38 2060773.0 -939000.0 -0.75 -0.7994 -0.9512 3118423 CBKinase1_018601 NCCn1c(N)c(C#N)c2nc3ccccc3nc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G02 compound treatment 2426148.0 -553000.0 -0.47 2712813.0 -287000.0 -0.23 -0.4919 -0.9462 1287876 CBKinase1_018602 Fc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G03 mock treatment 2609551.0 -370000.0 -0.31 2229126.0 -771000.0 -0.61 -0.6551 -0.9506 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G04 mock treatment 3313263.0 334000.0 0.28 2725217.0 -275000.0 -0.22 0.0442 0.1239 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G05 compound treatment 3014504.0 35000.0 0.03 2421444.0 -579000.0 -0.46 -0.3052 -0.6604 3628737 CBKinase1_018603 COc1cccc(CNc2nc3ccccc3n2C)c1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G06 compound treatment 2923942.0 -55500.0 -0.05 2727806.0 -272000.0 -0.22 -0.1865 -0.8404 3628738 CBKinase1_018604 COc1ccc(cc1)n2nnnc2SCC(=O)c3ccc(O)c(O)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G07 compound treatment 2940018.0 -39400.0 -0.03 2461800.0 -538000.0 -0.43 -0.3269 -0.7597 3628739 CBKinase1_018605 Cn1c(SCC(=O)Nc2sc3CCCCc3c2C#N)nnc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G08 compound treatment 2654569.0 -325000.0 -0.27 2603449.0 -397000.0 -0.32 -0.4173 -0.9975 3628740 CBKinase1_018606 CC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2cccc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G09 compound treatment 2674453.0 -305000.0 -0.26 2553403.0 -447000.0 -0.36 -0.4336 -0.9873 3628741 CBKinase1_018607 Cc1cc(Oc2ccccc2)nc(SCC(=O)Nc3ccccc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G10 compound treatment 2930484.0 -49000.0 -0.04 2711937.0 -288000.0 -0.23 -0.1916 -0.8212 3628742 CBKinase1_018608 Cc1c(NC(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G11 compound treatment 3081788.0 102000.0 0.09 2374714.0 -625000.0 -0.5 -0.2914 -0.5761 3628743 CBKinase1_018609 Brc1ccc2nc(NCc3ccccn3)nc(c4ccccc4)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G12 compound treatment 2643265.0 -336000.0 -0.28 2579521.0 -420000.0 -0.34 -0.4375 -0.9965 3628744 CBKinase1_018610 Cc1nc(SCC(=O)Nc2sc3CCCCc3c2C#N)nc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G13 compound treatment 2913486.0 -66000.0 -0.06 2590140.0 -410000.0 -0.33 -0.2704 -0.8158 3628745 CBKinase1_018611 Cc1nn(c(OC(=O)c2ccc(Cl)cc2)c1S(=O)(=O)c3ccccc3)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G14 compound treatment 2985358.0 5890.0 0.0 2569702.0 -430000.0 -0.34 -0.239 -0.6968 3628746 CBKinase1_018612 O=C(N(CCC#N)CCC#N)c1cc(nc2ccccc12)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G15 compound treatment 2947134.0 -32300.0 -0.03 2536587.0 -463000.0 -0.37 -0.2805 -0.7573 3628747 CBKinase1_018613 CN(CC(=O)Nc1cccc(I)c1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G16 compound treatment 2736605.0 -243000.0 -0.2 2682879.0 -317000.0 -0.25 -0.3236 -0.9946 3628748 CBKinase1_018614 COC(=O)c1c(C)c(sc1NC(=S)Nc2ccn(C)n2)C(=O)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G17 compound treatment 3024461.0 45000.0 0.04 2640636.0 -359000.0 -0.29 -0.1757 -0.6081 3628749 CBKinase1_018615 Cc1ccc(cc1)C(=O)CSc2nc(C)nc3sc4CCCCc4c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G18 compound treatment 2708443.0 -271000.0 -0.23 2843095.0 -157000.0 -0.13 -0.2501 -0.9597 3628750 CBKinase1_018616 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3cc4cc(Br)ccc4o3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G19 mock treatment 3277038.0 298000.0 0.25 3127978.0 128000.0 0.1 0.2496 0.9213 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G20 mock treatment 3256122.0 277000.0 0.23 3221846.0 222000.0 0.18 0.29 0.9906 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G21 compound treatment 3302904.0 323000.0 0.27 2197156.0 -803000.0 -0.64 -0.2596 -0.3731 1441858 CBKinase1_018617 Cc1sc2nc(SCc3nc4ccccc4[nH]3)n(c5ccccc5)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G22 compound treatment 2954773.0 -24700.0 -0.02 2799679.0 -200000.0 -0.16 -0.1276 -0.7926 3628751 CBKinase1_018618 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4cccc5cccnc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G23 compound treatment 2587408.0 -392000.0 -0.33 2698014.0 -302000.0 -0.24 -0.404 -0.9878 3628752 CBKinase1_018619 Cc1sc2nc(C)nc(SCC(=O)Nc3cc(C)ccc3C)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 G24 compound treatment 2270724.0 -709000.0 -0.6 1721387.0 -1280000.0 -1.02 -1.1434 -0.9677 3628753 CBKinase1_018620 [O-][N+](=O)c1cccc(NC(=S)NCc2cn(nc2c3ccccc3)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H01 compound treatment 2169640.0 -810000.0 -0.68 1994232.0 -1010000.0 -0.8 -1.0499 -0.9968 3628754 CBKinase1_018621 Cc1nnc(SCC(=O)Nc2ccnc3ccccc23)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H02 compound treatment 2780518.0 -199000.0 -0.17 2508067.0 -492000.0 -0.39 -0.3959 -0.9283 3628755 CBKinase1_018622 COc1cc(Cl)c(C)cc1NC(=O)C2CCC(=O)N2S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H03 mock treatment 2250807.0 -729000.0 -0.61 3298114.0 298000.0 0.24 -0.2666 -0.4046 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H04 mock treatment 3366353.0 387000.0 0.33 3249758.0 250000.0 0.2 0.3715 0.9719 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H05 compound treatment 2772632.0 -207000.0 -0.17 2902092.0 -97900.0 -0.08 -0.1786 -0.9342 3628756 CBKinase1_018623 Clc1ccccc1C(=O)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H06 compound treatment 2841610.0 -138000.0 -0.12 3167294.0 167000.0 0.13 0.0121 0.0681 3628757 CBKinase1_018624 CCOc1ccc(NC(=S)Nc2sc(C)c(CC)c2C(=O)OC)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H07 compound treatment 2936205.0 -43300.0 -0.04 3178723.0 179000.0 0.14 0.0749 0.5095 3628758 CBKinase1_018625 Cn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H08 compound treatment 2610059.0 -369000.0 -0.31 2982666.0 -17400.0 -0.01 -0.2301 -0.7378 3628759 CBKinase1_018626 NC(=O)CSc1nnnn1c2cccc(O)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H09 compound treatment 2765145.0 -214000.0 -0.18 2597576.0 -402000.0 -0.32 -0.3546 -0.9632 3628760 CBKinase1_018627 CCOC(=O)C1CCCN(C1)S(=O)(=O)c2ccc(Cl)c(Cl)c2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H10 compound treatment 2820676.0 -159000.0 -0.13 3095290.0 95300.0 0.08 -0.041 -0.2664 3628761 CBKinase1_018628 OC(=O)CCC(=O)Nc1cccc(c1)C(=O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H11 compound treatment 2622096.0 -357000.0 -0.3 3306329.0 306000.0 0.24 -0.0405 -0.1044 3628762 CBKinase1_018629 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)N2CCCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H12 compound treatment 2985446.0 5980.0 0.01 2660369.0 -340000.0 -0.27 -0.1879 -0.6938 3628763 CBKinase1_018630 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccncc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H13 compound treatment 2750828.0 -229000.0 -0.19 2885954.0 -114000.0 -0.09 -0.2007 -0.9411 3628764 CBKinase1_018631 Cc1ccc(NC(=O)CC2NCCNC2=O)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H14 compound treatment 2850233.0 -129000.0 -0.11 2942900.0 -57100.0 -0.05 -0.1093 -0.925 3628765 CBKinase1_018632 CS(=O)(=O)CCC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)Nc3cccc4ncccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H15 compound treatment 2757683.0 -222000.0 -0.19 2868874.0 -131000.0 -0.1 -0.2062 -0.9622 3628766 CBKinase1_018633 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(Cl)c3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H16 compound treatment 2827565.0 -152000.0 -0.13 3115044.0 115000.0 0.09 -0.0258 -0.1636 3628767 CBKinase1_018634 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc3oc(nc3c2)c4cccnc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H17 compound treatment 2917387.0 -62100.0 -0.05 3349982.0 350000.0 0.28 0.1602 0.5645 3628768 CBKinase1_018635 COc1ccc(cc1NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H18 compound treatment 2920917.0 -58500.0 -0.05 2922805.0 -77200.0 -0.06 -0.0784 -0.994 3628769 CBKinase1_018636 COc1cc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H19 mock treatment 2248523.0 -731000.0 -0.62 3528016.0 528000.0 0.42 -0.1384 -0.1854 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H20 mock treatment 2299324.0 -680000.0 -0.57 3604552.0 605000.0 0.48 -0.065 -0.0867 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H21 compound treatment 3568622.0 589000.0 0.5 3130559.0 131000.0 0.1 0.425 0.837 3628770 CBKinase1_018637 CCn1cc(CN(C)C(=S)Nc2ccc(OC)c(OC)c2)c(C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H22 compound treatment 3262191.0 283000.0 0.24 2843620.0 -156000.0 -0.12 0.0805 0.2991 3628771 CBKinase1_018638 Cc1c(NC(=O)COc2ccc(I)cc2)cccc1C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H23 compound treatment 3057673.0 78200.0 0.07 2311184.0 -689000.0 -0.55 -0.3416 -0.6177 3628772 CBKinase1_018639 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3OC(F)F)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 H24 compound treatment 2531221.0 -448000.0 -0.38 1947348.0 -1050000.0 -0.84 -0.8606 -0.9352 3628773 CBKinase1_018640 CC(Oc1ccccc1)C(=O)Nc2cc(ccc2O)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I01 compound treatment 2820284.0 -159000.0 -0.13 2370851.0 -629000.0 -0.5 -0.4495 -0.8659 3628774 CBKinase1_018641 [O-][N+](=O)c1cccc(c1)c2nn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I02 compound treatment 3160426.0 181000.0 0.15 3269983.0 270000.0 0.22 0.2601 0.9859 3628775 CBKinase1_018642 COc1ccccc1Nc2nc(N)nc(CSc3nnc(C)s3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I03 compound treatment 3332022.0 353000.0 0.3 3875356.0 875000.0 0.7 0.7036 0.9277 3628776 CBKinase1_018643 CC(C)CC(=O)Oc1c(c(C)nn1c2ccc(C)cc2C)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I04 compound treatment 3249156.0 270000.0 0.23 3956437.0 956000.0 0.76 0.6999 0.8798 3628777 CBKinase1_018644 CN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2c(C)cc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I05 mock treatment 3287203.0 308000.0 0.26 3872861.0 873000.0 0.7 0.6755 0.9097 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I06 mock treatment 3641694.0 662000.0 0.56 3979928.0 980000.0 0.78 0.9473 0.9865 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I07 compound treatment 3557483.0 578000.0 0.49 3936546.0 937000.0 0.75 0.8726 0.9787 3628778 CBKinase1_018645 NC(=O)CSc1nc2ccccc2n1Cc3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I08 compound treatment 3387933.0 408000.0 0.34 4099743.0 1100000.0 0.88 0.8634 0.9168 3628779 CBKinase1_018646 COc1ccc2c(C)c(CCC(=O)O)c(=O)oc2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I09 compound treatment 2921391.0 -58100.0 -0.05 4134534.0 1130000.0 0.9 0.6048 0.6678 3628780 CBKinase1_018647 [O-][N+](=O)c1cccc(c1)c2nn(CC(=O)Nc3ccc(F)cc3)c(=O)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I10 compound treatment 3286264.0 307000.0 0.26 4045677.0 1050000.0 0.83 0.7723 0.885 1314319 CBKinase1_018648 COC(=O)c1c(NC(=O)COc2c(C)cccc2C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I11 compound treatment 3428403.0 449000.0 0.38 3526879.0 527000.0 0.42 0.5647 0.9987 3628781 CBKinase1_018649 CC1(C2c3c(OC(=O)C21C(=O)c4ccco4)ccc5ccccc35)C(=O)c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I12 compound treatment 3541382.0 562000.0 0.47 4447178.0 1450000.0 1.15 1.1508 0.9228 3628782 CBKinase1_018650 COc1ccc(cc1OC)C(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I13 compound treatment 3433952.0 454000.0 0.38 3815295.0 815000.0 0.65 0.7306 0.9683 3628783 CBKinase1_018651 C(Oc1ccc(Oc2nc(nc(n2)N3CCOCC3)N4CCOCC4)nn1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I14 compound treatment 3594293.0 615000.0 0.52 3898096.0 898000.0 0.72 0.8729 0.9875 3628784 CBKinase1_018652 Cc1coc(C)c1C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I15 compound treatment 3332985.0 354000.0 0.3 4213454.0 1210000.0 0.97 0.8947 0.8841 3628785 CBKinase1_018653 Cc1nnc(SCc2cc(=O)[nH]c(Nc3nc(C)c4cccc(C)c4n3)n2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I16 compound treatment 3246559.0 267000.0 0.23 3952956.0 953000.0 0.76 0.6964 0.879 3628786 CBKinase1_018654 Cc1c(C)c(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)ccc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I17 compound treatment 3382022.0 403000.0 0.34 4171863.0 1170000.0 0.93 0.9005 0.9061 3628787 CBKinase1_018655 COC(=O)c1ccccc1NC(=O)Cn2cncc2c3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I18 compound treatment 3223348.0 244000.0 0.21 3631962.0 632000.0 0.5 0.5016 0.922 3628788 CBKinase1_018656 COC(=O)c1ccccc1NC(=O)NCc2ccc(cc2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I19 compound treatment 3526550.0 547000.0 0.46 3809473.0 809000.0 0.65 0.7825 0.9865 3628789 CBKinase1_018657 CN(CC(=O)Nc1c(C)cc(C)cc1C)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I20 compound treatment 3453375.0 474000.0 0.4 4300595.0 1300000.0 1.04 1.0157 0.9142 3628790 CBKinase1_018658 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(c3nc4ccccc4s3)c(Cl)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I21 mock treatment 3906282.0 927000.0 0.78 3280952.0 281000.0 0.22 0.7111 0.8745 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I22 mock treatment 3479864.0 500000.0 0.42 2904285.0 -95700.0 -0.08 0.2445 0.57 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I23 compound treatment 3331076.0 352000.0 0.3 2496116.0 -504000.0 -0.4 -0.0743 -0.1488 3628791 CBKinase1_018659 Fc1cccc(NC(=O)CSc2ncnc3sc4CCCCc4c23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 I24 compound treatment 2684063.0 -295000.0 -0.25 2087634.0 -912000.0 -0.73 -0.6904 -0.8981 3628792 CBKinase1_018660 Cc1ccccc1c2nnc(SCC(=O)Nc3cc(ccc3N4CCOCC4)C(F)(F)F)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J01 compound treatment 3366537.0 387000.0 0.33 2523592.0 -476000.0 -0.38 -0.0376 -0.0752 3628793 CBKinase1_018661 COCCCN1C(c2c(oc3ccc(Br)cc3c2=O)C1=O)c4cccc(c4)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J02 compound treatment 3859708.0 880000.0 0.74 3232074.0 232000.0 0.18 0.6558 0.8571 3628794 CBKinase1_018662 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc(Cl)c(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J03 compound treatment 3897226.0 918000.0 0.77 3580086.0 580000.0 0.46 0.8743 0.9696 3628795 CBKinase1_018663 COc1cccc(c1)n2nnnc2SCC(=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J04 compound treatment 3754278.0 775000.0 0.65 3266270.0 266000.0 0.21 0.6122 0.8909 3041126 CBKinase1_018664 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CN4CCN(CC4)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J05 mock treatment 4164501.0 1190000.0 1.0 3632509.0 632000.0 0.5 1.0633 0.9498 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J06 mock treatment 4001022.0 1020000.0 0.86 3814166.0 814000.0 0.65 1.0682 0.9902 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J07 compound treatment 3762603.0 783000.0 0.66 3643151.0 643000.0 0.51 0.8296 0.9921 3628796 CBKinase1_018665 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccccc2Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J08 compound treatment 3722164.0 743000.0 0.63 3698997.0 699000.0 0.56 0.8369 0.9983 1385100 CBKinase1_018666 COc1ccc(NC(=O)CSc2nnc(N)s2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J09 compound treatment 4420721.0 1440000.0 1.22 3630428.0 630000.0 0.5 1.2149 0.9236 3628797 CBKinase1_018667 Cc1c(CCC(=O)O)c(=O)oc2c(C)c(OCc3c(F)cccc3Cl)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J10 compound treatment 3701579.0 722000.0 0.61 3673774.0 674000.0 0.54 0.8104 0.998 3628798 CBKinase1_018668 COC(=O)c1cccc(COC(=O)c2ccccc2NC(=O)c3ccco3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J11 compound treatment 3862979.0 884000.0 0.75 3751206.0 751000.0 0.6 0.9503 0.9941 3628799 CBKinase1_018669 Clc1ccc(cc1)c2nnc(SCC(=O)c3ccc(Br)cc3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J12 compound treatment 4028776.0 1050000.0 0.89 3272877.0 273000.0 0.22 0.7796 0.8554 3628800 CBKinase1_018670 Cc1ccc(cc1)c2noc(CCCN3C(=O)c4ccccc4C3=O)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J13 compound treatment 4048316.0 1070000.0 0.9 3811201.0 811000.0 0.65 1.0947 0.9867 3628801 CBKinase1_018671 CC(=O)c1ccc(cc1)N2CCN(CC2)C(=S)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J14 compound treatment 3775802.0 796000.0 0.67 3685974.0 686000.0 0.55 0.8616 0.9948 3628802 CBKinase1_018672 CCn1c2ccccc2c3cc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J15 compound treatment 3801110.0 822000.0 0.69 4249483.0 1250000.0 1.0 1.1943 0.9843 3628803 CBKinase1_018673 Cc1cc(=O)oc2cc(NC(=S)NCc3ccccn3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J16 compound treatment 3767429.0 788000.0 0.66 3973570.0 974000.0 0.78 1.0187 0.997 3628804 CBKinase1_018674 COc1cc(OC)c(NC(=O)COc2ccc(cc2)[N+](=O)[O-])cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J17 compound treatment 3767266.0 788000.0 0.66 4544076.0 1540000.0 1.23 1.3401 0.9582 3628805 CBKinase1_018675 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2cccc(Br)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J18 compound treatment 3558190.0 579000.0 0.49 4388091.0 1390000.0 1.11 1.1275 0.9324 3628806 CBKinase1_018676 CC(Oc1ccc(Br)cc1)C(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J19 compound treatment 3603147.0 624000.0 0.53 4421637.0 1420000.0 1.13 1.1732 0.9391 3628807 CBKinase1_018677 COC(=O)c1cc(C)sc1NC(=S)Nc2ccn(Cc3ccc(Br)cc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J20 compound treatment 4095908.0 1120000.0 0.94 4196633.0 1200000.0 0.95 1.3403 1.0 3628808 CBKinase1_018678 Cc1cccc(C)c1OCC(=O)Nc2cccc(C(=O)O)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J21 mock treatment 3926235.0 947000.0 0.8 3922610.0 923000.0 0.74 1.0847 0.9992 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J22 mock treatment 3599269.0 620000.0 0.52 3973938.0 974000.0 0.78 0.9186 0.9815 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J23 compound treatment 3262762.0 283000.0 0.24 3676814.0 677000.0 0.54 0.5504 0.9329 3628809 CBKinase1_018679 COc1ccc2c(c1)c(=O)oc3cc(OCC(=O)Nc4cc(C)cc(C)c4)ccc32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 J24 compound treatment 2682367.0 -297000.0 -0.25 3259359.0 259000.0 0.21 -0.031 -0.0955 3628810 CBKinase1_018680 CC(Oc1ccc(Br)cc1)c2nc(no2)c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K01 compound treatment 1490388.0 -1490000.0 -1.26 1504921.0 -1500000.0 -1.19 -1.7308 -0.9997 3628811 CBKinase1_018681 CN(CC(=O)Nc1ccc(Br)cc1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K02 compound treatment 2561986.0 -417000.0 -0.35 2482271.0 -518000.0 -0.41 -0.5408 -0.9969 3628812 CBKinase1_018682 COc1cccc(OC)c1C(=O)NC(=S)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K03 compound treatment 1621559.0 -1360000.0 -1.15 1602743.0 -1400000.0 -1.11 -1.5974 -0.9999 3119466 CBKinase1_018683 Cc1ccc2n(CC(O)CNCc3ccccc3)c4CCCCc4c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K04 compound treatment 3079163.0 99700.0 0.08 3660704.0 661000.0 0.53 0.4318 0.8098 3628813 CBKinase1_018684 Cc1ccc(cc1NC(=O)CN(Cc2ccccc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K05 compound treatment 3601575.0 622000.0 0.52 2943909.0 -56100.0 -0.04 0.3394 0.6445 3628814 CBKinase1_018685 [O-][N+](=O)c1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K06 compound treatment 3035108.0 55600.0 0.05 3225982.0 226000.0 0.18 0.1605 0.8626 3628815 CBKinase1_018686 COc1ccc(OC(C)C(=O)Nc2ccccc2C#N)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K07 mock treatment 2967415.0 -12000.0 -0.01 3197086.0 197000.0 0.16 0.1039 0.66 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K08 mock treatment 2901882.0 -77600.0 -0.07 2904312.0 -95700.0 -0.08 -0.1002 -0.9971 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K09 compound treatment 2638314.0 -341000.0 -0.29 2842391.0 -158000.0 -0.13 -0.2923 -0.931 3628816 CBKinase1_018687 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)cc(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K10 compound treatment 2568270.0 -411000.0 -0.35 2920812.0 -79200.0 -0.06 -0.2899 -0.8223 3628817 CBKinase1_018688 Cc1nc(SCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)nc5CCCCc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K11 compound treatment 2456569.0 -523000.0 -0.44 2535603.0 -464000.0 -0.37 -0.5736 -0.9962 3628818 CBKinase1_018689 [O-][N+](=O)c1cccc(c1)c2nnc(SCC(=O)c3ccc(Br)cc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K12 compound treatment 2737432.0 -242000.0 -0.2 2859370.0 -141000.0 -0.11 -0.2236 -0.9602 3628819 CBKinase1_018690 COC(=O)c1ccc(NC(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K13 compound treatment 2650089.0 -329000.0 -0.28 2727334.0 -273000.0 -0.22 -0.3501 -0.9926 3628820 CBKinase1_018691 COc1ccc(cc1S(=O)(=O)NCc2ccccc2)c3nnc4c5ccccc5c(C)nn34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K14 compound treatment 2740677.0 -239000.0 -0.2 2411939.0 -588000.0 -0.47 -0.4739 -0.9288 3628821 CBKinase1_018692 CC(C)c1ccc(C)cc1OCCSc2nc3c(N)ncnc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K15 mock treatment 2820318.0 -159000.0 -0.13 2944287.0 -55700.0 -0.04 -0.1263 -0.8934 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K16 mock treatment 2837750.0 -142000.0 -0.12 2970527.0 -29500.0 -0.02 -0.1011 -0.8303 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K17 compound treatment 2339088.0 -640000.0 -0.54 2533261.0 -467000.0 -0.37 -0.645 -0.9834 3628822 CBKinase1_018693 Fc1ccccc1n2c(CSc3nnc4c5ccccc5nc(c6ccccc6)n34)nc7ccccc7c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K18 compound treatment 2871541.0 -108000.0 -0.09 2183741.0 -816000.0 -0.65 -0.5244 -0.7983 3628823 CBKinase1_018694 COc1ccc(NC(=O)NCCc2ccccc2OC)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K19 compound treatment 3172534.0 193000.0 0.16 2474185.0 -526000.0 -0.42 -0.1812 -0.403 3628824 CBKinase1_018695 Cn1nc(c2ccc(OCC(=O)Nc3cccnc3)cc2)c4ccccc4c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K20 compound treatment 2593714.0 -386000.0 -0.33 3820126.0 820000.0 0.65 0.2321 0.3179 3628825 CBKinase1_018696 COc1cc2c(cc1NC(=O)C3CCC(=O)N3S(=O)(=O)c4ccc(C)cc4)oc5ccccc52 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K21 compound treatment 3656357.0 677000.0 0.57 3168972.0 169000.0 0.13 0.4989 0.8505 3628826 CBKinase1_018697 CC1CCCCC1NC(=O)CSc2nnc(N)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K22 compound treatment 2371932.0 -608000.0 -0.51 3128522.0 129000.0 0.1 -0.2899 -0.5548 3628827 CBKinase1_018698 Clc1ccc(NS(=O)(=O)c2ccccc2)cc1CN3C(=O)c4ccccc4C3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K23 mock treatment 2988913.0 9450.0 0.01 2977654.0 -22400.0 -0.02 -0.007 -0.3569 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 K24 mock treatment 2090218.0 -889000.0 -0.75 2266930.0 -733000.0 -0.58 -0.9435 -0.9924 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L01 compound treatment 2610006.0 -369000.0 -0.31 2152679.0 -847000.0 -0.68 -0.6979 -0.9383 3628828 CBKinase1_018699 CCn1cc(NC(=S)Nc2cc(Cl)ccc2OC)c(n1)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L02 compound treatment 2843976.0 -135000.0 -0.11 3057558.0 57500.0 0.05 -0.0484 -0.3929 3628829 CBKinase1_018700 Cc1cccc(NC(=O)CC(N2CCOCC2)C(=O)O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L03 compound treatment 3203652.0 224000.0 0.19 3120748.0 121000.0 0.1 0.2018 0.9509 3628830 CBKinase1_018701 COC(=O)c1c(C)c(sc1NC(=S)Nc2cccc(NC(=O)C)c2)C(=O)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L04 compound treatment 3045994.0 66500.0 0.06 3101966.0 102000.0 0.08 0.0971 0.9837 3628831 CBKinase1_018702 COc1cc(C)c(Cl)cc1S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L05 compound treatment 3417200.0 438000.0 0.37 3213533.0 214000.0 0.17 0.3814 0.9382 1450306 CBKinase1_018703 O=S(=O)(Nc1ncccn1)c2ccc(NC(=S)Nc3ccc(Oc4ccccc4)cc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L06 compound treatment 2723269.0 -256000.0 -0.22 3409992.0 410000.0 0.33 0.0783 0.1997 3120026 CBKinase1_018704 CN(C)C(CC(=O)Nc1ccccc1C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L07 mock treatment 3375103.0 396000.0 0.33 2810199.0 -190000.0 -0.15 0.129 0.352 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L08 mock treatment 3164558.0 185000.0 0.16 3094090.0 94100.0 0.07 0.1634 0.9435 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L09 compound treatment 3157444.0 178000.0 0.15 2883528.0 -116000.0 -0.09 0.0405 0.2294 3628832 CBKinase1_018705 CCn1cc(C(C)NC(=S)Nc2ccc(OC)cc2OC)c(C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L10 compound treatment 3364969.0 386000.0 0.33 3151884.0 152000.0 0.12 0.3155 0.9094 3628833 CBKinase1_018706 O=C1N(CCCc2nc(no2)c3cccnc3)C(=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L11 compound treatment 3489331.0 510000.0 0.43 3664765.0 665000.0 0.53 0.6788 0.9946 3628834 CBKinase1_018707 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCc5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L12 compound treatment 3175766.0 196000.0 0.17 3104115.0 104000.0 0.08 0.1758 0.949 3628835 CBKinase1_018708 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3cccc(C#N)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L13 compound treatment 3250275.0 271000.0 0.23 2866454.0 -134000.0 -0.11 0.0862 0.3422 3628836 CBKinase1_018709 CC(=O)c1cccc(NC(=O)NCc2cc(C)n(C)n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L14 compound treatment 3178351.0 199000.0 0.17 3260950.0 261000.0 0.21 0.2657 0.9943 3628837 CBKinase1_018710 NC(=O)c1ccccc1NC(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L15 mock treatment 3313689.0 334000.0 0.28 3829153.0 829000.0 0.66 0.6666 0.9279 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L16 mock treatment 3522236.0 543000.0 0.46 3986817.0 987000.0 0.79 0.8799 0.9668 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L17 compound treatment 3367130.0 388000.0 0.33 3472113.0 472000.0 0.38 0.4973 0.9976 3628838 CBKinase1_018711 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L18 compound treatment 3460962.0 481000.0 0.41 3858717.0 859000.0 0.68 0.7711 0.969 3628839 CBKinase1_018712 Cc1ccc(OCC(=O)Nc2cccc3C(=O)NC(=O)c32)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L19 compound treatment 3766333.0 787000.0 0.66 2781207.0 -219000.0 -0.17 0.346 0.5042 3628840 CBKinase1_018713 COc1ccc(CCNC(=S)Nc2c(C)nn(C)c2C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L20 compound treatment 3513446.0 534000.0 0.45 2467726.0 -532000.0 -0.42 0.0185 0.0299 3628841 CBKinase1_018714 CC(Oc1ccc(Br)cc1)C(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L21 compound treatment 3667722.0 688000.0 0.58 3882706.0 883000.0 0.7 0.908 0.9954 3628842 CBKinase1_018715 COc1ccc(Cl)cc1NC(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L22 compound treatment 3342891.0 363000.0 0.31 4008836.0 1010000.0 0.8 0.7853 0.9126 3628843 CBKinase1_018716 Cc1cc(Cl)c(cc1OCC(=O)NC2CCCCC2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L23 mock treatment 3155864.0 176000.0 0.15 3537464.0 537000.0 0.43 0.4081 0.9 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 L24 mock treatment 2508012.0 -471000.0 -0.4 2643959.0 -356000.0 -0.28 -0.4819 -0.9863 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M01 compound treatment 2347457.0 -632000.0 -0.53 1970199.0 -1030000.0 -0.82 -0.9574 -0.9782 3628844 CBKinase1_018717 Cc1ccc(cc1C)C(=O)CCC(=O)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M02 compound treatment 2294734.0 -685000.0 -0.58 2369546.0 -630000.0 -0.5 -0.7637 -0.9976 3628845 CBKinase1_018718 COc1ccc(NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M03 compound treatment 2567143.0 -412000.0 -0.35 2648082.0 -352000.0 -0.28 -0.4443 -0.9943 1876362 CBKinase1_018719 CC(=O)Nc1ccc(OC(=O)CSc2nc3ccccc3s2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M04 compound treatment 2654867.0 -325000.0 -0.27 2634258.0 -366000.0 -0.29 -0.3997 -0.9995 3628846 CBKinase1_018720 Cc1ccc(C)c(c1)n2nnnc2SCC(=O)Nc3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M05 compound treatment 2728607.0 -251000.0 -0.21 2834592.0 -165000.0 -0.13 -0.2429 -0.9741 3628847 CBKinase1_018721 COC(=O)c1ccccc1NC(=O)CSc2nnnn2C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M06 compound treatment 2666481.0 -313000.0 -0.26 3159121.0 159000.0 0.13 -0.097 -0.3312 3628848 CBKinase1_018722 COc1ccc(cc1NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M07 compound treatment 2804498.0 -175000.0 -0.15 2946635.0 -53400.0 -0.04 -0.1344 -0.8753 3628849 CBKinase1_018723 COc1ccc(cc1O)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M08 compound treatment 2765806.0 -214000.0 -0.18 3016156.0 16100.0 0.01 -0.1183 -0.655 3628850 CBKinase1_018724 COc1cc(cc(OC)c1OC)C(=O)OCc2ccc(o2)c3cccc(Cl)c3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M09 mock treatment 2944663.0 -34800.0 -0.03 3173546.0 174000.0 0.14 0.077 0.5449 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M10 mock treatment 2932340.0 -47100.0 -0.04 3026267.0 26200.0 0.02 -0.0133 -0.2964 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M11 compound treatment 2809979.0 -169000.0 -0.14 2713211.0 -287000.0 -0.23 -0.2627 -0.9745 3628851 CBKinase1_018725 Ic1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M12 compound treatment 2968449.0 -11000.0 -0.01 2273011.0 -727000.0 -0.58 -0.4163 -0.7184 3628852 CBKinase1_018726 NS(=O)(=O)c1ccc(NC(=S)NCc2ccccn2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M13 mock treatment 3072483.0 93000.0 0.08 2273173.0 -727000.0 -0.58 -0.3542 -0.6058 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M14 mock treatment 3164650.0 185000.0 0.16 2925586.0 -74400.0 -0.06 0.0685 0.41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M15 compound treatment 2908232.0 -71200.0 -0.06 3403700.0 404000.0 0.32 0.185 0.5653 3628853 CBKinase1_018727 COc1ccc(Nc2nc(N)nc(CSc3nncn3C)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M16 compound treatment 3044849.0 65400.0 0.06 2655437.0 -345000.0 -0.27 -0.1552 -0.5541 3628854 CBKinase1_018728 CC(C)C(NC(=O)c1ccco1)C(=O)Nc2ccc(NC(=O)C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M17 compound treatment 3247111.0 268000.0 0.23 3160290.0 160000.0 0.13 0.25 0.9636 3628855 CBKinase1_018729 Cc1ccc(cc1Cl)c2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M18 compound treatment 3211746.0 232000.0 0.2 2920847.0 -79200.0 -0.06 0.0939 0.4563 3628856 CBKinase1_018730 Clc1ccc(cc1)c2nc(NCc3ccco3)n(n2)C(=O)c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M19 compound treatment 3024552.0 45100.0 0.04 2658248.0 -342000.0 -0.27 -0.1657 -0.6025 3628857 CBKinase1_018731 CN(CC(=O)Nc1ccc2ccccc2c1)S(=O)(=O)c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M20 compound treatment 2592064.0 -387000.0 -0.33 2409483.0 -591000.0 -0.47 -0.5639 -0.9841 3628858 CBKinase1_018732 CC(=O)c1cccc(NC(=S)NCc2cccnc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M21 compound treatment 3442533.0 463000.0 0.39 3234255.0 234000.0 0.19 0.4082 0.9429 3628859 CBKinase1_018733 CCCCN(C)S(=O)(=O)c1cc(ccc1OC)c2nnc3c4ccccc4c(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M22 compound treatment 2579469.0 -400000.0 -0.34 3261841.0 262000.0 0.21 -0.091 -0.2294 3628860 CBKinase1_018734 Cc1nn(Cc2cccc(Oc3ccccc3)c2)c(C)c1NC(=O)NC4(CC5CC6CC(C5)C4)C6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M23 compound treatment 2773532.0 -206000.0 -0.17 3043224.0 43200.0 0.03 -0.0985 -0.5561 3628861 CBKinase1_018735 Cc1nnc(SCc2nc(no2)c3ccc(Br)cc3)n1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 M24 compound treatment 2087009.0 -892000.0 -0.75 2229441.0 -771000.0 -0.61 -0.9666 -0.9949 3628862 CBKinase1_018736 CCOC(=O)c1cc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N01 compound treatment 2665228.0 -314000.0 -0.27 1874806.0 -1130000.0 -0.9 -0.8216 -0.8785 3628863 CBKinase1_018737 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N02 compound treatment 2636376.0 -343000.0 -0.29 3048324.0 48300.0 0.04 -0.1774 -0.6077 3628864 CBKinase1_018738 COC(=O)c1c(NC(=S)NCc2cc(C)n(C)n2)sc3CCCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N03 compound treatment 2828349.0 -151000.0 -0.13 2787978.0 -212000.0 -0.17 -0.2096 -0.9903 3628865 CBKinase1_018739 COc1ccc(C)cc1NC(=O)NCCc2ccc(OC)c(OC)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N04 compound treatment 3199074.0 220000.0 0.19 3239000.0 239000.0 0.19 0.2657 0.9999 3628866 CBKinase1_018740 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N05 compound treatment 3140451.0 161000.0 0.14 3286476.0 286000.0 0.23 0.2575 0.9692 3628867 CBKinase1_018741 COC(=O)c1cccc(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N06 compound treatment 3161293.0 182000.0 0.15 3254561.0 255000.0 0.2 0.2519 0.9905 3628868 CBKinase1_018742 Cc1cccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N07 compound treatment 3474441.0 495000.0 0.42 3328246.0 328000.0 0.26 0.4802 0.9746 3628869 CBKinase1_018743 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccc2Cl)n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N08 compound treatment 3572600.0 593000.0 0.5 3174369.0 174000.0 0.14 0.452 0.8706 3628870 CBKinase1_018744 COc1ccccc1Nc2nc(N)nc(CN(C)C3CCCCC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N09 mock treatment 3632226.0 653000.0 0.55 3524638.0 525000.0 0.42 0.685 0.9908 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N10 mock treatment 3416866.0 437000.0 0.37 3341980.0 342000.0 0.27 0.4536 0.9889 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N11 compound treatment 3241650.0 262000.0 0.22 3541004.0 541000.0 0.43 0.4613 0.9519 3628871 CBKinase1_018745 Cc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N12 compound treatment 3562742.0 583000.0 0.49 3622599.0 623000.0 0.5 0.6988 1.0 3628872 CBKinase1_018746 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc3oc(nc3c2)c4ccncc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N13 mock treatment 3233041.0 254000.0 0.21 3297022.0 297000.0 0.24 0.3186 0.9987 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N14 mock treatment 3454848.0 475000.0 0.4 3701747.0 702000.0 0.56 0.679 0.9867 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N15 compound treatment 3554925.0 575000.0 0.49 3475327.0 475000.0 0.38 0.6111 0.9925 3628873 CBKinase1_018747 COC(=O)c1c(NC(=S)Nc2nc(C)cc(C)n2)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N16 compound treatment 3495936.0 516000.0 0.44 3227539.0 228000.0 0.18 0.4363 0.9245 3628874 CBKinase1_018748 COC(=O)COc1cccc(NC(=O)c2ccc(cc2)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N17 compound treatment 3557544.0 578000.0 0.49 3888182.0 888000.0 0.71 0.8454 0.9834 3628875 CBKinase1_018749 COc1ccc(cc1S(=O)(=O)NCc2ccccn2)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N18 compound treatment 3423502.0 444000.0 0.37 3091551.0 91500.0 0.07 0.3164 0.8293 3628876 CBKinase1_018750 CC(Oc1ccc(Br)cc1)C(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N19 compound treatment 3734157.0 755000.0 0.64 3092274.0 92300.0 0.07 0.5021 0.7836 3628877 CBKinase1_018751 Cc1cc(C)cc(c1)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N20 compound treatment 3197827.0 218000.0 0.18 3946332.0 946000.0 0.75 0.6636 0.8547 3628878 CBKinase1_018752 [O-][N+](=O)c1ccc(OCc2nc(no2)c3ccccn3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N21 compound treatment 3288271.0 309000.0 0.26 2819668.0 -180000.0 -0.14 0.0825 0.2774 3628879 CBKinase1_018753 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc(Cl)c(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N22 compound treatment 3038585.0 59100.0 0.05 3137874.0 138000.0 0.11 0.113 0.9361 3628880 CBKinase1_018754 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2Cl)c3nc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N23 compound treatment 2867625.0 -112000.0 -0.09 3525972.0 526000.0 0.42 0.2297 0.5346 3628881 CBKinase1_018755 COC(=O)c1ccc(C(=O)OC)c(NC(=O)Nc2cc(OC)ccc2OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 N24 compound treatment 2677248.0 -302000.0 -0.25 2674154.0 -326000.0 -0.26 -0.3639 -1.0 3628882 CBKinase1_018756 Cc1ccc(C)c(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O01 compound treatment 2816467.0 -163000.0 -0.14 3021255.0 21200.0 0.02 -0.0852 -0.6154 3628883 CBKinase1_018757 CSc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O02 compound treatment 3322057.0 343000.0 0.29 3398287.0 398000.0 0.32 0.4288 0.9989 3628884 CBKinase1_018758 CN(CC(=O)Nc1ccccc1Br)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O03 compound treatment 3523251.0 544000.0 0.46 2992237.0 -7780.0 -0.01 0.32 0.6975 3628885 CBKinase1_018759 CC(C)(C)c1ccc(OCC(=O)NCc2ccco2)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O04 compound treatment 3317028.0 338000.0 0.28 3299755.0 300000.0 0.24 0.3703 0.9962 3628886 CBKinase1_018760 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc-4c(Cc5ccccc54)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O05 compound treatment 3457751.0 478000.0 0.4 2818224.0 -182000.0 -0.14 0.1828 0.4265 3628887 CBKinase1_018761 O=c1n(c(CSc2nc(nc3ccccc23)C4CC4)nc5ccccc15)c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O06 compound treatment 3389663.0 410000.0 0.35 3031179.0 31200.0 0.02 0.2622 0.7559 3628888 CBKinase1_018762 CC(=O)c1cccc(NC(=S)NCc2ccccn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O07 compound treatment 3739682.0 760000.0 0.64 3252687.0 253000.0 0.2 0.5958 0.8865 3628889 CBKinase1_018763 Clc1ccccc1NC(=O)CSc2nnc(c3cccs3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O08 compound treatment 3329131.0 350000.0 0.29 2956729.0 -43300.0 -0.03 0.1842 0.6202 3628890 CBKinase1_018764 Cc1ccc(Cl)cc1N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O09 compound treatment 3488117.0 509000.0 0.43 2594009.0 -406000.0 -0.32 0.0746 0.1387 3628891 CBKinase1_018765 COc1ccc(Nc2nc(N)nc(CSCCO)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O10 compound treatment 3252219.0 273000.0 0.23 2983083.0 -16900.0 -0.01 0.1531 0.6645 1610095 CBKinase1_018766 COc1ccc(CCNC(=S)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O11 mock treatment 3888546.0 909000.0 0.77 3066654.0 66600.0 0.05 0.5798 0.7543 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O12 mock treatment 4120594.0 1140000.0 0.96 3566830.0 567000.0 0.45 1.0001 0.9405 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O13 compound treatment 4256432.0 1280000.0 1.08 3451229.0 451000.0 0.36 1.0159 0.8946 3628892 CBKinase1_018767 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(CC#N)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O14 compound treatment 3565753.0 586000.0 0.49 2874235.0 -126000.0 -0.1 0.2788 0.5525 3628893 CBKinase1_018768 CCc1c(C)sc(NC(=S)Nc2nc(C)cc(C)n2)c1C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O15 compound treatment 4123738.0 1140000.0 0.97 3743533.0 744000.0 0.59 1.1015 0.9726 3628894 CBKinase1_018769 CC(C(=O)Nc1ccc(CC#N)cc1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O16 compound treatment 4200643.0 1220000.0 1.03 3763624.0 764000.0 0.61 1.1587 0.9685 3628895 CBKinase1_018770 COc1ccc(C)cc1NC(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O17 compound treatment 4546078.0 1570000.0 1.32 4024949.0 1020000.0 0.82 1.512 0.9733 3628896 CBKinase1_018771 CCC(Sc1nnnn1C)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O18 compound treatment 4306996.0 1330000.0 1.12 4015604.0 1020000.0 0.81 1.3642 0.9873 3628897 CBKinase1_018772 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccc(I)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O19 compound treatment 4972041.0 1990000.0 1.68 4491105.0 1490000.0 1.19 2.0288 0.9856 3628898 CBKinase1_018773 O=C(CSc1ncnc2sc3CCCCc3c12)N4CCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O20 compound treatment 4658337.0 1680000.0 1.42 4016536.0 1020000.0 0.81 1.5743 0.9649 3628899 CBKinase1_018774 COC(=O)c1ccccc1NC(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O21 compound treatment 4375376.0 1400000.0 1.18 3490333.0 490000.0 0.39 1.1089 0.8939 3628900 CBKinase1_018775 COC(=O)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O22 compound treatment 4095140.0 1120000.0 0.94 2955239.0 -44800.0 -0.04 0.6402 0.6798 3628901 CBKinase1_018776 OC(=O)c1ccc(CSc2nnc([nH]2)c3ccco3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O23 compound treatment 3126245.0 147000.0 0.12 3900268.0 900000.0 0.72 0.5949 0.817 3628902 CBKinase1_018777 Cc1sc2nc(SCC(=O)NCC3CCCO3)n(c4ccc(F)cc4)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 O24 compound treatment 3016595.0 37100.0 0.03 3658127.0 658000.0 0.52 0.3931 0.748 1984376 CBKinase1_018778 CC(C)CC(NC(=O)c1ccco1)C(=O)Nc2ccc3OCCOc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P01 compound treatment 2120095.0 -859000.0 -0.72 2527633.0 -472000.0 -0.38 -0.7788 -0.9534 3628903 CBKinase1_018779 [O-][N+](=O)c1cccc(NC(=O)Nc2nn(Cc3c(F)cccc3Cl)cc2Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P02 compound treatment 3395386.0 416000.0 0.35 2608126.0 -392000.0 -0.31 0.0272 0.0579 3628904 CBKinase1_018780 OCCNc1nc2ccccc2n1CCOc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P03 compound treatment 3374881.0 395000.0 0.33 3267621.0 268000.0 0.21 0.3867 0.9767 3628905 CBKinase1_018781 Cc1ccc(cc1F)C(=O)c2oc3ccccc3c2NC(=O)c4cc5ccccc5oc4=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P04 compound treatment 2429157.0 -550000.0 -0.46 2869175.0 -131000.0 -0.1 -0.402 -0.8449 3628906 CBKinase1_018782 Cc1ccc(cc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P05 compound treatment 2808971.0 -170000.0 -0.14 2360056.0 -640000.0 -0.51 -0.4624 -0.8725 3628907 CBKinase1_018783 COc1ccc(NC(=O)NCc2cccnc2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P06 compound treatment 2981752.0 2290.0 0.0 2940179.0 -59800.0 -0.05 -0.0324 -0.6779 3628908 CBKinase1_018784 NC(=O)CSc1ncn(n1)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P07 compound treatment 2809277.0 -170000.0 -0.14 2720228.0 -280000.0 -0.22 -0.2592 -0.9773 3628909 CBKinase1_018785 Cc1cccc(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P08 compound treatment 2945131.0 -34300.0 -0.03 2840661.0 -159000.0 -0.13 -0.1103 -0.8466 3628910 CBKinase1_018786 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P09 compound treatment 2774850.0 -205000.0 -0.17 2599095.0 -401000.0 -0.32 -0.348 -0.9582 3628911 CBKinase1_018787 CSc1ccccc1NC(=O)CSc2nnnn2c3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P10 compound treatment 2834462.0 -145000.0 -0.12 2376701.0 -623000.0 -0.5 -0.4378 -0.8556 3628912 CBKinase1_018788 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cccc(NC(=O)c3ccc(Cl)cc3Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P11 mock treatment 2865125.0 -114000.0 -0.1 2897850.0 -102000.0 -0.08 -0.1258 -0.9965 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P12 mock treatment 2744715.0 -235000.0 -0.2 2919326.0 -80700.0 -0.06 -0.1855 -0.891 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P13 compound treatment 3253581.0 274000.0 0.23 2860997.0 -139000.0 -0.11 0.0851 0.3321 3628913 CBKinase1_018789 CCOC(=O)c1c(NC(=S)NCc2ccccn2)sc3CCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P14 compound treatment 2908580.0 -70900.0 -0.06 2751961.0 -248000.0 -0.2 -0.1821 -0.8815 3628914 CBKinase1_018790 Cc1c(NC(=O)COc2ccc(cc2)C(C)(C)C)cccc1C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P15 compound treatment 3792372.0 813000.0 0.69 3453771.0 454000.0 0.36 0.7406 0.9553 3628915 CBKinase1_018791 COc1ccc(NC(=O)NCc2ccc(cc2)C(=O)O)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P16 compound treatment 3775973.0 797000.0 0.67 3411293.0 411000.0 0.33 0.7069 0.9456 3628916 CBKinase1_018792 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cccc(c3nc4ccccc4o3)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P17 compound treatment 3121095.0 142000.0 0.12 3007989.0 7970.0 0.01 0.089 0.7437 3628917 CBKinase1_018793 Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P18 compound treatment 3853820.0 874000.0 0.74 3684766.0 685000.0 0.55 0.9074 0.989 3628918 CBKinase1_018794 COc1ccc(c(c1)[N+](=O)[O-])S(=O)(=O)Nc2ccc(Br)c3cccnc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P19 compound treatment 4248873.0 1270000.0 1.07 3832662.0 833000.0 0.66 1.2264 0.9735 3628919 CBKinase1_018795 Cc1c(CCC(=O)O)c(=O)oc2c(C)c(OCc3cccc4ccccc34)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P20 compound treatment 4123918.0 1140000.0 0.97 3724713.0 725000.0 0.58 1.091 0.9698 3628920 CBKinase1_018796 COc1cc2c(cc1NC(=O)CCCN3C(=O)c4ccccc4C3=O)oc5ccccc52 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P21 compound treatment 4286888.0 1310000.0 1.1 3635920.0 636000.0 0.51 1.1382 0.9378 3628921 CBKinase1_018797 Fc1cccc(F)c1NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P22 compound treatment 3795947.0 816000.0 0.69 3291929.0 292000.0 0.23 0.6515 0.8962 3628922 CBKinase1_018798 CC(Oc1ccc(Br)cc1)C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P23 compound treatment 3692580.0 713000.0 0.6 3490061.0 490000.0 0.39 0.7015 0.9781 3628923 CBKinase1_018799 COc1ccc(cc1OC)N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2382 P24 compound treatment 3253074.0 274000.0 0.23 2884285.0 -116000.0 -0.09 0.098 0.3942 3628924 CBKinase1_018800 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccccc3C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A01 compound treatment 2306995.0 -664000.0 -0.56 1968392.0 -1000000.0 -0.8 -0.9618 -0.9849 3628925 CBKinase1_018801 CCc1cc(C(=O)OC)c(NC(=O)CC2NCCNC2=O)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A02 compound treatment 2833483.0 -138000.0 -0.12 3473180.0 501000.0 0.4 0.2003 0.4814 3628926 CBKinase1_018802 CCOC(=O)c1cc(sc1NC(=S)Nc2cnccn2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A03 compound treatment 3641980.0 671000.0 0.57 3183526.0 212000.0 0.17 0.5193 0.8797 3628927 CBKinase1_018803 CSc1ccccc1NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A04 compound treatment 2372557.0 -599000.0 -0.51 2038553.0 -933000.0 -0.74 -0.8831 -0.9822 3628928 CBKinase1_018804 Cc1ccc(cc1C)N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A05 compound treatment 2909178.0 -62200.0 -0.05 1907843.0 -1060000.0 -0.85 -0.6367 -0.7494 3628929 CBKinase1_018805 CCOC(=O)c1ccccc1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A06 compound treatment 3317795.0 346000.0 0.29 2990897.0 19000.0 0.02 0.2174 0.7428 3628930 CBKinase1_018806 COc1ccccc1N2CCN(CCNC(=O)Nc3cccc(C)c3C)CC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A07 compound treatment 2009681.0 -962000.0 -0.81 1995649.0 -976000.0 -0.78 -1.1238 -0.9998 3628931 CBKinase1_018807 COC(=O)c1ccccc1NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A08 compound treatment 2513384.0 -458000.0 -0.39 2347241.0 -625000.0 -0.5 -0.6252 -0.9921 3628932 CBKinase1_018808 CCn1cc(C(C)NC(=O)Nc2ccccc2C(=O)OC)c(C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A09 compound treatment 2568661.0 -403000.0 -0.34 2511180.0 -461000.0 -0.37 -0.4998 -0.9992 3628933 CBKinase1_018809 Cc1nnc(SCC(=O)Nc2ccc(C#N)cc2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A10 compound treatment 2417633.0 -554000.0 -0.47 2347484.0 -624000.0 -0.5 -0.6821 -0.9995 3628934 CBKinase1_018810 COc1ccc(NC(=O)Nc2nn(Cc3c(F)cccc3Cl)cc2Br)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A11 compound treatment 2776009.0 -195000.0 -0.16 2427020.0 -545000.0 -0.43 -0.4236 -0.912 2069034 CBKinase1_018811 OC(=O)CNS(=O)(=O)c1ccc(Cl)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A12 compound treatment 2625221.0 -346000.0 -0.29 2558213.0 -414000.0 -0.33 -0.4396 -0.9982 3628935 CBKinase1_018812 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cccc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A13 mock treatment 2926988.0 -44400.0 -0.04 2494932.0 -477000.0 -0.38 -0.2952 -0.773 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A14 mock treatment 2808712.0 -163000.0 -0.14 2701580.0 -270000.0 -0.22 -0.2493 -0.9763 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A15 compound treatment 2788439.0 -183000.0 -0.15 2619582.0 -352000.0 -0.28 -0.3076 -0.9602 3628936 CBKinase1_018813 COC(=O)c1cc(C)sc1NC(=S)Nc2cnn(C)c2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A16 compound treatment 2609449.0 -362000.0 -0.31 2767218.0 -205000.0 -0.16 -0.3312 -0.9569 3628937 CBKinase1_018814 Cc1cccc(OCC(O)CNC(C)(C)CO)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A17 compound treatment 3126665.0 155000.0 0.13 2751732.0 -220000.0 -0.18 -0.0314 -0.1435 3628938 CBKinase1_018815 COC(=O)c1ccc(NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A18 compound treatment 2870284.0 -101000.0 -0.09 2777688.0 -194000.0 -0.15 -0.1697 -0.9605 3628939 CBKinase1_018816 [O-][N+](=O)c1cccc(c1)C(=O)N(CCC#N)CCC#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A19 compound treatment 3076943.0 106000.0 0.09 2587563.0 -384000.0 -0.31 -0.1536 -0.4815 3628940 CBKinase1_018817 COCCNC(=O)c1ccccc1NC(=O)c2cccc([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A20 compound treatment 3067355.0 96000.0 0.08 3040802.0 69000.0 0.05 0.0961 0.9822 3628941 CBKinase1_018818 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2cccc(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A21 compound treatment 2848545.0 -123000.0 -0.1 3088923.0 117000.0 0.09 -0.0073 -0.0521 3628942 CBKinase1_018819 CCn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A22 compound treatment 2801041.0 -170000.0 -0.14 2757675.0 -214000.0 -0.17 -0.2223 -0.9963 3628943 CBKinase1_018820 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccccc2C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A23 compound treatment 2596895.0 -374000.0 -0.32 2936024.0 -35800.0 -0.03 -0.2435 -0.7679 3628944 CBKinase1_018821 Clc1ccc(cc1)c2nc(NCc3ccco3)n(n2)C(=O)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 A24 compound treatment 2466611.0 -505000.0 -0.43 2632834.0 -339000.0 -0.27 -0.4921 -0.9759 1277457 CBKinase1_018822 Cc1c(NC(=S)NCc2ccccn2)c(=O)n(c3ccccc3)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B01 compound treatment 2811288.0 -160000.0 -0.14 2538912.0 -433000.0 -0.35 -0.3395 -0.9161 1418355 CBKinase1_018823 COc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(C)cc3)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B02 compound treatment 2853933.0 -117000.0 -0.1 2765962.0 -206000.0 -0.16 -0.1861 -0.9708 1984291 CBKinase1_018824 Nc1ncn(Cc2ccccc2)c3nc(SCC(=O)O)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B03 compound treatment 2679500.0 -292000.0 -0.25 3306231.0 334000.0 0.27 0.0144 0.0397 3628945 CBKinase1_018825 Cc1ccc(N(CC(=O)Nc2ccccc2Sc3ccccc3)S(=O)(=O)C)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B04 compound treatment 3449192.0 478000.0 0.4 4071271.0 1100000.0 0.88 0.9046 0.9379 3628946 CBKinase1_018826 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(F)cc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B05 compound treatment 3450124.0 479000.0 0.4 3765753.0 794000.0 0.63 0.733 0.9765 3628947 CBKinase1_018827 COc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B06 compound treatment 4193589.0 1220000.0 1.03 3344829.0 373000.0 0.3 0.9392 0.8753 3628948 CBKinase1_018828 COc1ccc(NC(=S)NCCc2ccccc2OC)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B07 compound treatment 2370984.0 -600000.0 -0.51 2820729.0 -151000.0 -0.12 -0.4432 -0.8515 3628949 CBKinase1_018829 Fc1ccccc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B08 compound treatment 3342036.0 371000.0 0.31 3406054.0 434000.0 0.35 0.4658 0.9987 3628950 CBKinase1_018830 CSc1cccc(NC(=O)CSc2nnc(C)s2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B09 compound treatment 3454823.0 483000.0 0.41 3243768.0 272000.0 0.22 0.4416 0.9562 3628951 CBKinase1_018831 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2cccc(Cl)c2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B10 compound treatment 3210328.0 239000.0 0.2 3172373.0 201000.0 0.16 0.2556 0.9934 3628952 CBKinase1_018832 [O-][N+](=O)c1ncn(Cc2ccccn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B11 compound treatment 3026593.0 55300.0 0.05 3349507.0 378000.0 0.3 0.2458 0.807 3628953 CBKinase1_018833 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2cccc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B12 compound treatment 3748240.0 777000.0 0.66 4216955.0 1250000.0 0.99 1.1651 0.9797 3628954 CBKinase1_018834 Cc1nnc(s1)N2C(c3c(oc4ccc(Cl)cc4c3=O)C2=O)c5cccnc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B13 mock treatment 3291294.0 320000.0 0.27 3771467.0 800000.0 0.64 0.6415 0.9269 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B14 mock treatment 3539894.0 569000.0 0.48 4214435.0 1240000.0 0.99 1.0394 0.9446 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B15 compound treatment 3408723.0 437000.0 0.37 3942890.0 971000.0 0.77 0.8081 0.9426 3628955 CBKinase1_018835 COc1ccc(cc1[N+](=O)[O-])S(=O)(=O)N(C(=O)C)c2ccc3oc4CCC(C)Cc4c3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B16 compound treatment 3293794.0 322000.0 0.27 3783600.0 812000.0 0.65 0.6498 0.9259 3628956 CBKinase1_018836 COc1cc(c(OC)cc1Cl)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B17 compound treatment 3004712.0 33400.0 0.03 3460527.0 489000.0 0.39 0.2953 0.7562 3628957 CBKinase1_018837 CC(Sc1nc(=O)cc(N)n1c2ccccc2)C(=O)Nc3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B18 compound treatment 3344598.0 373000.0 0.31 3558169.0 586000.0 0.47 0.5531 0.9815 3628958 CBKinase1_018838 Cc1cccc(NC(=O)CSc2nnc(c3ccco3)n2C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B19 compound treatment 3627917.0 657000.0 0.55 3697980.0 726000.0 0.58 0.8009 0.9998 3628959 CBKinase1_018839 Cc1c(Cl)cccc1NC(=O)c2ccc(OCC(=O)Nc3ccc(F)cc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B20 compound treatment 3597112.0 626000.0 0.53 3164681.0 193000.0 0.15 0.4819 0.8766 3628960 CBKinase1_018840 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3ccco3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B21 compound treatment 3706774.0 735000.0 0.62 3750659.0 779000.0 0.62 0.8776 1.0 3628961 CBKinase1_018841 Clc1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B22 compound treatment 3627556.0 656000.0 0.55 3774161.0 802000.0 0.64 0.8436 0.9974 3628962 CBKinase1_018842 [O-][N+](=O)c1ccc(OCc2nc(no2)c3ccncc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B23 compound treatment 3228678.0 257000.0 0.22 3533125.0 561000.0 0.45 0.4698 0.9449 3628963 CBKinase1_018843 CCOC(=O)c1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 B24 compound treatment 2782647.0 -189000.0 -0.16 2834839.0 -137000.0 -0.11 -0.1898 -0.9831 3628964 CBKinase1_018844 [O-][N+](=O)c1ccc(OCc2nc(no2)c3cccnc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C01 compound treatment 2422025.0 -549000.0 -0.46 2737090.0 -235000.0 -0.19 -0.4599 -0.9204 3628965 CBKinase1_018845 FC(F)(F)c1cccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C02 compound treatment 2962784.0 -8560.0 -0.01 2326948.0 -645000.0 -0.51 -0.3686 -0.717 3628966 CBKinase1_018846 Cc1ccc2oc3C(=O)N(CCCN4CCOCC4)C(c3c(=O)c2c1)c5ccc(cc5)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C03 compound treatment 2489989.0 -481000.0 -0.41 2867527.0 -104000.0 -0.08 -0.3459 -0.8346 3628967 CBKinase1_018847 Clc1ccc(Oc2ccccc2)c(NC(=O)CN3C(=O)c4ccccc4S3(=O)=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C04 compound treatment 2853464.0 -118000.0 -0.1 2467586.0 -504000.0 -0.4 -0.3545 -0.8562 3628968 CBKinase1_018848 COC(=O)C1(CCCCC1)C(O)C(=O)c2ccc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C05 compound treatment 1995410.0 -976000.0 -0.82 1647909.0 -1320000.0 -1.06 -1.3283 -0.9925 3628969 CBKinase1_018849 COC(=O)c1ccc(NC(=O)CSc2nncc3ccccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C06 compound treatment 3162049.0 191000.0 0.16 2988755.0 16900.0 0.01 0.1233 0.7637 3628970 CBKinase1_018850 COC(=O)c1cc(sc1NC(=S)Nc2ccn(C)n2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C07 compound treatment 2442583.0 -529000.0 -0.45 2759633.0 -212000.0 -0.17 -0.435 -0.9119 3628971 CBKinase1_018851 Cc1nnc(SCC(=O)Nc2cc(Cl)ccc2Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C08 compound treatment 2665567.0 -306000.0 -0.26 2722719.0 -249000.0 -0.2 -0.3228 -0.9917 3628972 CBKinase1_018852 Cc1nc(sc1C)N2C(c3c(oc4ccc(C)cc4c3=O)C2=O)c5ccc(OCC(=O)N)cc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C09 compound treatment 2958664.0 -12700.0 -0.01 2803997.0 -168000.0 -0.13 -0.1022 -0.7612 3628973 CBKinase1_018853 COc1ccc(CN2C(=O)C(O)(CC(=O)c3c(C)n[nH]c3C)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C10 compound treatment 2685360.0 -286000.0 -0.24 2790139.0 -182000.0 -0.14 -0.273 -0.9702 3628974 CBKinase1_018854 CSc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C11 mock treatment 2920698.0 -50600.0 -0.04 3010446.0 38600.0 0.03 -0.0085 -0.1606 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C12 mock treatment 2763421.0 -208000.0 -0.18 3038801.0 67000.0 0.05 -0.0863 -0.4706 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C13 compound treatment 2747360.0 -224000.0 -0.19 3068694.0 96800.0 0.08 -0.079 -0.3871 3628975 CBKinase1_018855 CCSc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C14 compound treatment 2797462.0 -174000.0 -0.15 2882514.0 -89300.0 -0.07 -0.1541 -0.9449 3628976 CBKinase1_018856 COC(=O)c1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C15 mock treatment 1912311.0 -1060000.0 -0.89 3000707.0 28900.0 0.02 -0.6154 -0.6887 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C16 mock treatment 2866694.0 -105000.0 -0.09 2815394.0 -156000.0 -0.12 -0.1506 -0.9857 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C17 compound treatment 2727677.0 -244000.0 -0.21 2751113.0 -221000.0 -0.18 -0.2697 -0.997 3628977 CBKinase1_018857 Cc1cccc(NC(=O)CSc2nnc3c4ccccc4nc(c5ccccc5)n23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C18 compound treatment 2827949.0 -143000.0 -0.12 2757897.0 -214000.0 -0.17 -0.2061 -0.9858 3628978 CBKinase1_018858 COc1ccc(OC)c(NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C19 compound treatment 2966068.0 -5270.0 0.0 2899145.0 -72700.0 -0.06 -0.0441 -0.7591 1986236 CBKinase1_018859 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccc(cc4)S(=O)(=O)N5CCCCCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C20 compound treatment 2707832.0 -264000.0 -0.22 2800421.0 -171000.0 -0.14 -0.2538 -0.9727 3628979 CBKinase1_018860 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C21 compound treatment 2561966.0 -409000.0 -0.35 2737511.0 -234000.0 -0.19 -0.3762 -0.9584 3628980 CBKinase1_018861 CSc1ccccc1NC(=O)CN(c2ccccc2Br)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C22 compound treatment 2622025.0 -349000.0 -0.29 2838882.0 -133000.0 -0.11 -0.2833 -0.9047 3628981 CBKinase1_018862 Clc1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C23 compound treatment 2482031.0 -489000.0 -0.41 2516757.0 -455000.0 -0.36 -0.5483 -0.9979 3628982 CBKinase1_018863 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2nnc(c3cccnc3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 C24 compound treatment 2359300.0 -612000.0 -0.52 2324869.0 -647000.0 -0.52 -0.7297 -1.0 3628983 CBKinase1_018864 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3C)nnc2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D01 compound treatment 2229311.0 -742000.0 -0.63 2297813.0 -674000.0 -0.54 -0.8225 -0.9971 3628984 CBKinase1_018865 Cc1ccc(C)c(c1)N(CC(=O)Nc2cccc([N+](=O)[O-])c2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D02 compound treatment 2808239.0 -163000.0 -0.14 2612039.0 -360000.0 -0.29 -0.3001 -0.9434 3628985 CBKinase1_018866 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccccc3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D03 compound treatment 2826887.0 -144000.0 -0.12 2621558.0 -350000.0 -0.28 -0.2836 -0.9309 3628986 CBKinase1_018867 COc1ccc(CCNC(=O)Nc2ccc(cc2)C(=O)C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D04 compound treatment 2968115.0 -3230.0 0.0 3266980.0 295000.0 0.24 0.1644 0.6989 3628987 CBKinase1_018868 Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1Sc4nc5ccccc5s4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D05 compound treatment 3626798.0 655000.0 0.55 3649112.0 677000.0 0.54 0.7726 0.9999 3628988 CBKinase1_018869 Fc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D06 compound treatment 3066163.0 94800.0 0.08 3547004.0 575000.0 0.46 0.3807 0.8181 3628989 CBKinase1_018870 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)c(Cl)c1)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D07 compound treatment 2853272.0 -118000.0 -0.1 3302957.0 331000.0 0.26 0.1162 0.4119 3628990 CBKinase1_018871 [O-][N+](=O)c1ccccc1C(=O)NCCNC(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D08 compound treatment 2782086.0 -189000.0 -0.16 3360211.0 388000.0 0.31 0.106 0.3044 3628991 CBKinase1_018872 [O-][N+](=O)c1cccc(c1)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D09 compound treatment 3322332.0 351000.0 0.3 3572114.0 600000.0 0.48 0.5477 0.9734 3628992 CBKinase1_018873 COc1ccccc1C(=O)NCCNC(=O)c2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D10 compound treatment 3221327.0 250000.0 0.21 3480622.0 509000.0 0.41 0.4358 0.9536 3628993 CBKinase1_018874 CCn1c2ccccc2c3cc(NC(=O)C4CCC(=O)N4S(=O)(=O)c5ccc(C)cc5)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D11 mock treatment 3112114.0 141000.0 0.12 3646432.0 675000.0 0.54 0.4642 0.843 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D12 mock treatment 3203205.0 232000.0 0.2 3494059.0 522000.0 0.42 0.4326 0.9407 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D13 compound treatment 3154318.0 183000.0 0.15 3694682.0 723000.0 0.58 0.5165 0.866 3628994 CBKinase1_018875 COC(=O)c1ccc(Cl)c(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D14 compound treatment 2727080.0 -244000.0 -0.21 3611448.0 640000.0 0.51 0.2148 0.3906 3628995 CBKinase1_018876 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3Cl)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D15 mock treatment 3046320.0 75000.0 0.06 3520342.0 548000.0 0.44 0.3538 0.8011 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D16 mock treatment 3038188.0 66800.0 0.06 3399382.0 428000.0 0.34 0.2808 0.8131 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D17 compound treatment 3052127.0 80800.0 0.07 3433516.0 462000.0 0.37 0.3084 0.824 3628996 CBKinase1_018877 CC(Sc1nc(c(C#N)c(=O)[nH]1)c2ccccc2)C(=O)Nc3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D18 compound treatment 3072892.0 102000.0 0.09 3447923.0 476000.0 0.38 0.3289 0.8455 3628997 CBKinase1_018878 COc1ccc(cc1)n2c(SCC(=O)NC3CCCCC3)nnc2c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D19 compound treatment 3114609.0 143000.0 0.12 3430372.0 459000.0 0.37 0.3439 0.8933 3628998 CBKinase1_018879 COc1ccc(Cl)cc1NC(=S)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D20 compound treatment 3320645.0 349000.0 0.29 3831348.0 859000.0 0.69 0.6927 0.929 3628999 CBKinase1_018880 OC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D21 compound treatment 2812339.0 -159000.0 -0.13 2893126.0 -78700.0 -0.06 -0.1392 -0.9401 3629000 CBKinase1_018881 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCC5CCCO5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D22 compound treatment 2771988.0 -199000.0 -0.17 3061520.0 89700.0 0.07 -0.0684 -0.3742 3629001 CBKinase1_018882 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D23 compound treatment 2569353.0 -402000.0 -0.34 2808552.0 -163000.0 -0.13 -0.3318 -0.9135 3629002 CBKinase1_018883 Cc1nnc(SCC(=O)Nc2ccc(C)c(c2)[N+](=O)[O-])s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 D24 compound treatment 2493342.0 -478000.0 -0.4 2523087.0 -449000.0 -0.36 -0.538 -0.9982 3629003 CBKinase1_018884 COc1ccccc1CC(=O)Nc2ccc3C(=O)NC(=O)c3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E01 mock treatment 1887363.0 -1080000.0 -0.91 743341.0 -2230000.0 -1.78 -1.9025 -0.9523 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E02 mock treatment 1086441.0 -1880000.0 -1.59 1016571.0 -1960000.0 -1.56 -2.2262 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E03 compound treatment 1144800.0 -1830000.0 -1.54 1107063.0 -1860000.0 -1.49 -2.1404 -0.9998 3629004 CBKinase1_018885 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)N2CCNCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E04 compound treatment 1208117.0 -1760000.0 -1.49 1169508.0 -1800000.0 -1.44 -2.0675 -0.9998 3629005 CBKinase1_018886 CC(Sc1nc(C)cc(C)n1)C(=O)Nc2cccc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E05 compound treatment 1182766.0 -1790000.0 -1.51 1402789.0 -1570000.0 -1.25 -1.9511 -0.9957 3629006 CBKinase1_018887 Cc1coc(C)c1C(=O)CC2(O)C(=O)N(CCc3ccccc3)c4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E06 compound treatment 1655258.0 -1320000.0 -1.11 1794330.0 -1180000.0 -0.94 -1.4486 -0.9965 3629007 CBKinase1_018888 O=C(N1CCOCC1)c2ccccc2Oc3nnnn3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E07 compound treatment 1201236.0 -1770000.0 -1.49 1717546.0 -1250000.0 -1.0 -1.7627 -0.981 3629008 CBKinase1_018889 CC(Sc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N)C(=O)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E08 compound treatment 1644158.0 -1330000.0 -1.12 1781796.0 -1190000.0 -0.95 -1.4623 -0.9966 3629009 CBKinase1_018890 CCOc1ccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E09 mock treatment 1767870.0 -1200000.0 -1.02 2326114.0 -646000.0 -0.51 -1.0817 -0.9504 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E10 mock treatment 1930813.0 -1040000.0 -0.88 2314005.0 -658000.0 -0.52 -0.9914 -0.9697 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E11 compound treatment 2066936.0 -904000.0 -0.76 2435549.0 -536000.0 -0.43 -0.8417 -0.9625 3629010 CBKinase1_018891 COc1cc(ccc1NC(=S)NCc2cc(C)n(C)n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E12 compound treatment 2150336.0 -821000.0 -0.69 2406853.0 -565000.0 -0.45 -0.8081 -0.9783 3629011 CBKinase1_018892 Brc1ccccc1NC(=O)Cn2cnc3sc4CCCCc4c3c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E13 compound treatment 2116517.0 -855000.0 -0.72 2556596.0 -415000.0 -0.33 -0.7439 -0.9376 3629012 CBKinase1_018893 Cc1cc(C(=O)NCc2ccco2)c3cc(F)ccc3n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E14 compound treatment 2156951.0 -814000.0 -0.69 2631868.0 -340000.0 -0.27 -0.6773 -0.9173 3629013 CBKinase1_018894 CC(C)c1cc(I)ccc1NC(=O)CSc2nnc(C)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E15 compound treatment 2057701.0 -914000.0 -0.77 2578955.0 -393000.0 -0.31 -0.7664 -0.9213 3629014 CBKinase1_018895 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3cc(Cl)ccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E16 compound treatment 2400825.0 -571000.0 -0.48 2983770.0 11900.0 0.01 -0.3336 -0.693 3629015 CBKinase1_018896 Cc1cc(CNC(=O)NC2(CC3CC4CC(C3)C2)C4)nn1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E17 mock treatment 2362915.0 -608000.0 -0.51 2883942.0 -87900.0 -0.07 -0.4124 -0.7963 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E18 mock treatment 2395182.0 -576000.0 -0.49 2285088.0 -687000.0 -0.55 -0.7307 -0.9982 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E19 compound treatment 2578758.0 -393000.0 -0.33 2503014.0 -469000.0 -0.37 -0.4984 -0.9982 3629016 CBKinase1_018897 Fc1ccc(NC(=O)NCc2ccccn2)c(F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E20 compound treatment 2396691.0 -575000.0 -0.48 2720482.0 -251000.0 -0.2 -0.4844 -0.9236 3629017 CBKinase1_018898 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2ccc(Oc3ccccc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E21 compound treatment 2604585.0 -367000.0 -0.31 2590665.0 -381000.0 -0.3 -0.4336 -1.0 3629018 CBKinase1_018899 COc1ccc(OC)c(c1)C(C)NC(=O)Nc2ccc(cc2OC)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E22 compound treatment 2419544.0 -552000.0 -0.47 2796388.0 -175000.0 -0.14 -0.428 -0.8807 3629019 CBKinase1_018900 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3cccc4cccnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E23 compound treatment 2231175.0 -740000.0 -0.62 3136645.0 165000.0 0.13 -0.3486 -0.5464 3629020 CBKinase1_018901 CCOC(=O)c1sc(NC(=S)Nc2ccc3OCCOc3c2)c(C(=O)OCC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 E24 compound treatment 1774749.0 -1200000.0 -1.01 2215954.0 -756000.0 -0.6 -1.1397 -0.9696 3629021 CBKinase1_018902 Cc1c(NC(=O)CN(c2cccc(Br)c2)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F01 mock treatment 1805726.0 -1170000.0 -0.98 795444.0 -2180000.0 -1.73 -1.9218 -0.9638 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F02 mock treatment 1102363.0 -1870000.0 -1.58 965695.0 -2010000.0 -1.6 -2.2454 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F03 compound treatment 957373.0 -2010000.0 -1.7 2007921.0 -964000.0 -0.77 -1.7445 -0.9357 3629022 CBKinase1_018903 CSc1ccccc1n2nnnc2SCC(=O)Nc3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F04 compound treatment 3378307.0 407000.0 0.34 1119699.0 -1850000.0 -1.48 -0.8011 -0.5286 3629023 CBKinase1_018904 Cc1nnc(SCC(=O)Nc2ccc(cc2)N3CCOCC3)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F05 compound treatment 2524307.0 -447000.0 -0.38 1208322.0 -1760000.0 -1.41 -1.2605 -0.8662 3629024 CBKinase1_018905 Cc1ccc(cc1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F06 compound treatment 2777642.0 -194000.0 -0.16 1579980.0 -1390000.0 -1.11 -0.9 -0.8026 3629025 CBKinase1_018906 CCOC(=O)c1c(NC(=S)Nc2ccsc2C(=O)OC)sc(C)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F07 compound treatment 1398744.0 -1570000.0 -1.33 1554003.0 -1420000.0 -1.13 -1.7371 -0.9968 3629026 CBKinase1_018907 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F08 compound treatment 1835701.0 -1140000.0 -0.96 1975452.0 -996000.0 -0.79 -1.2389 -0.9957 2068080 CBKinase1_018908 CN(C)C(CC(=O)Nc1c(C)cccc1C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F09 mock treatment 2774301.0 -197000.0 -0.17 2184312.0 -788000.0 -0.63 -0.5614 -0.8645 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F10 mock treatment 2075431.0 -896000.0 -0.76 2144573.0 -827000.0 -0.66 -1.0006 -0.9977 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F11 compound treatment 2009488.0 -962000.0 -0.81 2146278.0 -826000.0 -0.66 -1.039 -0.9946 3629027 CBKinase1_018909 COc1cccc(NC(=O)COc2ccc(cc2OC)C(=S)N3CCN(C)CC3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F12 compound treatment 2146858.0 -824000.0 -0.7 2573398.0 -398000.0 -0.32 -0.7163 -0.9369 3629028 CBKinase1_018910 Cc1ccccc1n2nnnc2SCC(=O)Nc3cccc(Cl)c3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F13 compound treatment 1978539.0 -993000.0 -0.84 2035121.0 -937000.0 -0.75 -1.1201 -0.9984 3629029 CBKinase1_018911 CC(=O)Nc1cccc(NC(=S)NCc2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F14 compound treatment 2025875.0 -945000.0 -0.8 2240335.0 -732000.0 -0.58 -0.9762 -0.9881 3629030 CBKinase1_018912 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nccc(C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F15 compound treatment 1929699.0 -1040000.0 -0.88 2295268.0 -677000.0 -0.54 -1.0026 -0.9725 1984248 CBKinase1_018913 Clc1cccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F16 compound treatment 2155295.0 -816000.0 -0.69 2494050.0 -478000.0 -0.38 -0.756 -0.961 3629031 CBKinase1_018914 COC(=O)c1ccc(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F17 mock treatment 2165004.0 -806000.0 -0.68 2220779.0 -751000.0 -0.6 -0.9042 -0.998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F18 mock treatment 2415916.0 -555000.0 -0.47 2329493.0 -642000.0 -0.51 -0.6933 -0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F19 compound treatment 3144920.0 174000.0 0.15 2935625.0 -36200.0 -0.03 0.0831 0.5569 3629032 CBKinase1_018915 CSc1nnnn1c2ccccc2SCCSc3nnnn3c4ccccc4SC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F20 compound treatment 3155980.0 185000.0 0.16 2645184.0 -327000.0 -0.26 -0.074 -0.2438 3629033 CBKinase1_018916 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc(Cl)c(c2)c3nc4ncccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F21 compound treatment 2333911.0 -637000.0 -0.54 2411692.0 -560000.0 -0.45 -0.6959 -0.9957 3629034 CBKinase1_018917 COC(=O)c1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F22 compound treatment 2374473.0 -597000.0 -0.5 2335337.0 -637000.0 -0.51 -0.7147 -1.0 3629035 CBKinase1_018918 COc1ccc(cc1OC)c2noc(CCCN3C(=O)c4ccccc4C3=O)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F23 compound treatment 2124422.0 -847000.0 -0.71 2452039.0 -520000.0 -0.41 -0.7981 -0.9664 3629036 CBKinase1_018919 COc1ccc(C)cc1N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 F24 compound treatment 1659949.0 -1310000.0 -1.11 2139049.0 -833000.0 -0.66 -1.2515 -0.9702 3629037 CBKinase1_018920 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G01 compound treatment 2109842.0 -861000.0 -0.73 2340603.0 -631000.0 -0.5 -0.8696 -0.9839 3629038 CBKinase1_018921 COC(=O)c1ccccc1NC(=O)Nc2ncn(Cc3ccc(Cl)c(Cl)c3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G02 compound treatment 2514684.0 -457000.0 -0.39 2698796.0 -273000.0 -0.22 -0.4263 -0.9635 3629039 CBKinase1_018922 COC(=O)c1c(NC(=O)c2ccccc2N(C)S(=O)(=O)c3ccccc3)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G03 mock treatment 2270695.0 -701000.0 -0.59 2481693.0 -490000.0 -0.39 -0.6941 -0.9798 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G04 mock treatment 2635780.0 -336000.0 -0.28 2599405.0 -372000.0 -0.3 -0.4101 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G05 compound treatment 2310394.0 -661000.0 -0.56 3211486.0 240000.0 0.19 -0.2592 -0.4398 3629040 CBKinase1_018923 COc1ccc(CCNC(=S)Nc2ccncc2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G06 compound treatment 2637341.0 -334000.0 -0.28 2942690.0 -29200.0 -0.02 -0.2156 -0.7628 3629041 CBKinase1_018924 CN(c1ccccc1C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G07 compound treatment 2703940.0 -267000.0 -0.23 3293461.0 322000.0 0.26 0.0218 0.0638 3629042 CBKinase1_018925 COCCNC(=O)c1ccccc1NC(=O)c2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G08 compound treatment 2852944.0 -118000.0 -0.1 2755908.0 -216000.0 -0.17 -0.1923 -0.9665 3629043 CBKinase1_018926 COC(=O)c1c(NC(=S)NCc2ccco2)sc3CC(C)CCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G09 compound treatment 2387020.0 -584000.0 -0.49 2812503.0 -159000.0 -0.13 -0.4383 -0.8612 3629044 CBKinase1_018927 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccccc2Sc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G10 compound treatment 2620489.0 -351000.0 -0.3 2620961.0 -351000.0 -0.28 -0.407 -0.9996 3629045 CBKinase1_018928 CC(C)c1ccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G11 compound treatment 2806366.0 -165000.0 -0.14 2624031.0 -348000.0 -0.28 -0.2944 -0.9492 3629046 CBKinase1_018929 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2F)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G12 compound treatment 2642009.0 -329000.0 -0.28 2540103.0 -432000.0 -0.34 -0.4398 -0.9944 3629047 CBKinase1_018930 [O-][N+](=O)c1cccc(NC(=S)Nc2nn(Cc3ccc(Cl)cc3Cl)cc2Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G13 compound treatment 2537215.0 -434000.0 -0.37 2478048.0 -494000.0 -0.39 -0.5372 -0.9994 3629048 CBKinase1_018931 COc1c(Cl)cc(cc1Cl)C(=O)Nc2sc3CCCc3c2C(=O)NCc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G14 compound treatment 2462409.0 -509000.0 -0.43 2272571.0 -699000.0 -0.56 -0.6977 -0.9917 3629049 CBKinase1_018932 COc1ccc(NC(=S)N(C)Cc2c(C)nn(C)c2C)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G15 compound treatment 2642086.0 -329000.0 -0.28 2382315.0 -590000.0 -0.47 -0.5286 -0.9685 3629050 CBKinase1_018933 NC(=O)CSc1nnc(c2cc(Br)ccc2O)n1CC=C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G16 compound treatment 2588442.0 -383000.0 -0.32 2663163.0 -309000.0 -0.25 -0.4024 -0.991 3629051 CBKinase1_018934 COC(=O)c1ccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G17 compound treatment 2785577.0 -186000.0 -0.16 2345407.0 -626000.0 -0.5 -0.4639 -0.8864 3629052 CBKinase1_018935 Cc1sc2ncn(CC(=O)Nc3ccccc3C)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G18 compound treatment 2538630.0 -433000.0 -0.36 2149542.0 -822000.0 -0.66 -0.7215 -0.9618 3629053 CBKinase1_018936 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G19 mock treatment 3171199.0 200000.0 0.17 3564361.0 593000.0 0.47 0.4531 0.9037 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G20 mock treatment 2969594.0 -1750.0 0.0 2667466.0 -304000.0 -0.24 -0.1726 -0.7114 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G21 compound treatment 2953178.0 -18200.0 -0.02 2311931.0 -660000.0 -0.53 -0.3828 -0.7274 3629054 CBKinase1_018937 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc4CCCCc4c3)c5ccccc25)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G22 compound treatment 2145348.0 -826000.0 -0.7 2278057.0 -694000.0 -0.55 -0.8837 -0.9935 3629055 CBKinase1_018938 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G23 compound treatment 2278889.0 -692000.0 -0.58 2601566.0 -370000.0 -0.3 -0.6217 -0.95 3629056 CBKinase1_018939 Cc1nnc(SCC(=O)Nc2cccc(I)c2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 G24 compound treatment 1937423.0 -1030000.0 -0.87 1975074.0 -997000.0 -0.79 -1.1784 -0.9989 3629057 CBKinase1_018940 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2cc(Cl)cc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H01 compound treatment 2279355.0 -692000.0 -0.58 1939886.0 -1030000.0 -0.82 -0.9943 -0.9859 3629058 CBKinase1_018941 Cc1cccc(c1)C(=O)NCc2nnc(S)n2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H02 compound treatment 2662310.0 -309000.0 -0.26 2603127.0 -369000.0 -0.29 -0.3921 -0.9982 3629059 CBKinase1_018942 CCN1CCN(CC1)C(=O)c2ccccc2N(Cc3ccccc3)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H03 mock treatment 3175271.0 204000.0 0.17 3076113.0 104000.0 0.08 0.1804 0.9443 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H04 mock treatment 3134029.0 163000.0 0.14 3232299.0 260000.0 0.21 0.2438 0.9798 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H05 compound treatment 3231467.0 260000.0 0.22 3009261.0 37400.0 0.03 0.1762 0.7959 3629060 CBKinase1_018943 CCOc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4cc(OC)c(OC)c(OC)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H06 compound treatment 3267720.0 296000.0 0.25 3165630.0 194000.0 0.15 0.286 0.9732 3629061 CBKinase1_018944 NS(=O)(=O)c1ccc(NC(=S)Nc2nn(Cc3ccc(Cl)cc3Cl)cc2Cl)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H07 compound treatment 3279547.0 308000.0 0.26 3138725.0 167000.0 0.13 0.2779 0.9516 3629062 CBKinase1_018945 Clc1ccc(Cl)c(NC(=O)c2ccc(OCC(=O)Nc3cccc4ccccc34)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H08 compound treatment 3425858.0 455000.0 0.38 3190515.0 219000.0 0.17 0.3943 0.9363 3629063 CBKinase1_018946 COC(=O)c1ccc(Cl)c(NC(=O)Cc2ccccc2[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H09 compound treatment 3061534.0 90200.0 0.08 3224491.0 253000.0 0.2 0.1962 0.9114 3629064 CBKinase1_018947 CC(SC1=NC(=O)C(NC(=O)C)C(=O)N1)C(=O)Nc2cccc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H10 compound treatment 3395414.0 424000.0 0.36 2848100.0 -124000.0 -0.1 0.1832 0.4937 3629065 CBKinase1_018948 COC(=O)c1ccc(NC(=O)CN(c2ccccc2Br)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H11 compound treatment 3297366.0 326000.0 0.28 2824168.0 -148000.0 -0.12 0.1112 0.3718 3629066 CBKinase1_018949 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)Nc3ccccc3C(=O)NC4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H12 compound treatment 3300761.0 329000.0 0.28 3172381.0 201000.0 0.16 0.3095 0.9655 3629067 CBKinase1_018950 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H13 compound treatment 3146659.0 175000.0 0.15 2768280.0 -204000.0 -0.16 -0.0102 -0.0463 3629068 CBKinase1_018951 OC(=O)C(CC(=O)Nc1ccccc1)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H14 compound treatment 3341293.0 370000.0 0.31 3011900.0 40100.0 0.03 0.2432 0.7754 3629069 CBKinase1_018952 Cc1nnc(SCC(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H15 compound treatment 3181346.0 210000.0 0.18 2992122.0 20300.0 0.02 0.1367 0.7684 3629070 CBKinase1_018953 [O-][N+](=O)c1cccc(NC(=S)Nc2nn(Cc3ccc(Cl)c(Cl)c3)cc2Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H16 compound treatment 3305341.0 334000.0 0.28 2672904.0 -299000.0 -0.24 0.0307 0.0833 3629071 CBKinase1_018954 Cc1ccc(NS(=O)(=O)c2cccc(c2)C(=O)Nc3ccccc3C(=O)O)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H17 compound treatment 3366799.0 395000.0 0.33 2998542.0 26700.0 0.02 0.2509 0.7507 3629072 CBKinase1_018955 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3ccccc3F)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H18 compound treatment 3069461.0 98100.0 0.08 2801146.0 -171000.0 -0.14 -0.0377 -0.2366 3629073 CBKinase1_018956 CCN(CC)C(=O)c1sc(NC(=S)Nc2cnccn2)c(C(=O)OC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H19 mock treatment 3526808.0 555000.0 0.47 2994748.0 22900.0 0.02 0.3442 0.7341 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H20 mock treatment 3230855.0 260000.0 0.22 2798623.0 -173000.0 -0.14 0.0572 0.2208 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H21 compound treatment 3140680.0 169000.0 0.14 2845664.0 -126000.0 -0.1 0.0299 0.1711 3629074 CBKinase1_018957 CSc1cccc(NC(=O)CSc2nnc(c3ccco3)n2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H22 compound treatment 2838674.0 -133000.0 -0.11 2714785.0 -257000.0 -0.2 -0.224 -0.9595 3629075 CBKinase1_018958 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2nnn(C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H23 compound treatment 2619797.0 -352000.0 -0.3 2586944.0 -385000.0 -0.31 -0.4266 -0.9999 3629076 CBKinase1_018959 OC(COc1ccc2ccccc2c1)CN3CCN(CC3)S(=O)(=O)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 H24 compound treatment 2326662.0 -645000.0 -0.54 2234567.0 -737000.0 -0.59 -0.8 -0.9992 3629077 CBKinase1_018960 CN(CC(=O)Nc1cc(C)ccc1O)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I01 compound treatment 2293231.0 -678000.0 -0.57 2079686.0 -892000.0 -0.71 -0.9073 -0.9942 3629078 CBKinase1_018961 COc1cc(c(OC)cc1Cl)n2nnnc2SCC(=O)Nc3cccc(Cl)c3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I02 compound treatment 3360010.0 389000.0 0.33 3031336.0 59500.0 0.05 0.2653 0.801 3629079 CBKinase1_018962 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I03 compound treatment 2741651.0 -230000.0 -0.19 3827278.0 855000.0 0.68 0.3451 0.4869 3629080 CBKinase1_018963 CC(C)c1cc(Br)ccc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I04 compound treatment 2877189.0 -94200.0 -0.08 3087410.0 116000.0 0.09 0.009 0.0738 3629081 CBKinase1_018964 Cc1ccc(cc1C)N(CC(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I05 mock treatment 2851017.0 -120000.0 -0.1 2698092.0 -274000.0 -0.22 -0.2261 -0.9394 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I06 mock treatment 3352940.0 382000.0 0.32 3102642.0 131000.0 0.1 0.3013 0.8906 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I07 compound treatment 2990810.0 19500.0 0.02 3129189.0 157000.0 0.13 0.1003 0.7929 3629082 CBKinase1_018965 O=C(Nc1cccc2ccccc12)c3ccccc3NS(=O)(=O)c4cccc5cccnc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I08 compound treatment 2955751.0 -15600.0 -0.01 3058389.0 86500.0 0.07 0.0395 0.5622 3629083 CBKinase1_018966 CS(=O)(=O)N(CC(=O)Nc1ccccc1Sc2ccccc2)c3cccc(Br)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I09 compound treatment 3086192.0 115000.0 0.1 2984538.0 12700.0 0.01 0.0757 0.7767 3629084 CBKinase1_018967 COc1ccccc1OCCSc2nnc3[nH]c4ccccc4n23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I10 compound treatment 3003137.0 31800.0 0.03 3148485.0 177000.0 0.14 0.1185 0.8269 3629085 CBKinase1_018968 CS(=O)(=O)N(CC(=O)Nc1ccccc1Sc2ccccc2)c3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I11 compound treatment 2900235.0 -71100.0 -0.06 3097748.0 126000.0 0.1 0.0285 0.2442 3629086 CBKinase1_018969 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cc(F)ccc3C)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I12 compound treatment 2907226.0 -64100.0 -0.05 3046726.0 74900.0 0.06 0.004 0.0492 3629087 CBKinase1_018970 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I13 compound treatment 3117564.0 146000.0 0.12 2981716.0 9870.0 0.01 0.0928 0.7507 3629088 CBKinase1_018971 COc1ccccc1CCNC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I14 compound treatment 2959238.0 -12100.0 -0.01 2900322.0 -71500.0 -0.06 -0.0475 -0.8207 3629089 CBKinase1_018972 COc1ccccc1N(CC(=O)Nc2cccc([N+](=O)[O-])c2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I15 compound treatment 2928921.0 -42400.0 -0.04 3070663.0 98800.0 0.08 0.0304 0.3513 3629090 CBKinase1_018973 Cc1cccc(NC(=O)CC2NCCNC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I16 compound treatment 3041367.0 70000.0 0.06 2922413.0 -49400.0 -0.04 0.0139 0.1958 3629091 CBKinase1_018974 CCOC(=O)c1c(NC(=S)NCc2cc(C)n(C)n2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I17 compound treatment 3140010.0 169000.0 0.14 3056789.0 84900.0 0.07 0.1485 0.9423 3629092 CBKinase1_018975 CCc1c(C)sc(NC(=S)NCc2cc(C)n(C)n2)c1C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I18 compound treatment 3008750.0 37400.0 0.03 2630717.0 -341000.0 -0.27 -0.1699 -0.6209 3629093 CBKinase1_018976 COC(=O)c1ccc(Cl)c(NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I19 compound treatment 3320425.0 349000.0 0.29 3090930.0 119000.0 0.09 0.2753 0.8899 3629094 CBKinase1_018977 CC(=O)c1cccc(NC(=O)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I20 compound treatment 2962709.0 -8630.0 -0.01 2311441.0 -660000.0 -0.53 -0.3774 -0.7168 3629095 CBKinase1_018978 CS(=O)(=O)N(CC(=O)Nc1ccccc1Sc2ccccc2)c3ccc(Cl)c(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I21 mock treatment 2463654.0 -508000.0 -0.43 2057964.0 -914000.0 -0.73 -0.8179 -0.9679 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I22 mock treatment 3004160.0 32800.0 0.03 2423567.0 -548000.0 -0.44 -0.2894 -0.661 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I23 compound treatment 2671547.0 -300000.0 -0.25 2723333.0 -249000.0 -0.2 -0.3189 -0.9927 3629096 CBKinase1_018979 CCc1c(C)sc(NC(=S)Nc2ccsc2C(=O)OC)c1C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 I24 compound treatment 2485726.0 -486000.0 -0.41 2262550.0 -709000.0 -0.57 -0.6894 -0.9875 3629097 CBKinase1_018980 COC(=O)c1cc(Cc2ccccc2)sc1NC(=S)Nc3cccc(NC(=O)C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J01 compound treatment 2501459.0 -470000.0 -0.4 2723162.0 -249000.0 -0.2 -0.4204 -0.9487 3629098 CBKinase1_018981 CCn1c2nnc(SCC(=O)Nc3ccc(C)cc3)n2c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J02 compound treatment 2752845.0 -218000.0 -0.18 3153437.0 182000.0 0.14 -0.028 -0.1194 3629099 CBKinase1_018982 COC(=O)c1c(C)c(C)sc1NC(=S)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J03 compound treatment 3145501.0 174000.0 0.15 3173713.0 202000.0 0.16 0.2176 0.999 3629100 CBKinase1_018983 Cc1cc(C)cc(NC(=O)CC2NCCNC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J04 compound treatment 2969242.0 -2100.0 0.0 3275062.0 303000.0 0.24 0.1696 0.7019 3629101 CBKinase1_018984 COc1ccc(C)cc1NC(=S)NCc2cnn(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J05 mock treatment 3161258.0 190000.0 0.16 3193802.0 222000.0 0.18 0.2384 0.9988 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J06 mock treatment 3231378.0 260000.0 0.22 3333856.0 362000.0 0.29 0.3591 0.9908 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J07 compound treatment 3117472.0 146000.0 0.12 3201711.0 230000.0 0.18 0.2167 0.9814 3629102 CBKinase1_018985 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(Cl)cc3)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J08 compound treatment 3367857.0 397000.0 0.33 3092204.0 120000.0 0.1 0.3043 0.8747 3629103 CBKinase1_018986 COc1ccc(cc1NC(=O)c2ccccc2N(C)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J09 compound treatment 3073888.0 103000.0 0.09 3432158.0 460000.0 0.37 0.3206 0.8505 3629104 CBKinase1_018987 COc1ccc(cc1NC(=O)C(C)N2C(=O)C3CC=C(Cl)CC3C2=O)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J10 compound treatment 3079065.0 108000.0 0.09 2994578.0 22700.0 0.02 0.0771 0.8317 3629105 CBKinase1_018988 Clc1ccc(Cn2cc(NC(=S)NCC3CCCO3)cn2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J11 compound treatment 3158483.0 187000.0 0.16 3062371.0 90500.0 0.07 0.1626 0.9371 3629106 CBKinase1_018989 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J12 compound treatment 2923588.0 -47800.0 -0.04 2870060.0 -102000.0 -0.08 -0.0858 -0.9478 3629107 CBKinase1_018990 CN(C)c1nc(N)nc(CSc2nnnn2c3cccc4ccccc34)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J13 compound treatment 3126956.0 156000.0 0.13 3092802.0 121000.0 0.1 0.161 0.9885 3629108 CBKinase1_018991 COC(=O)c1c(NC(=S)NCc2ccco2)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J14 compound treatment 2974267.0 2930.0 0.0 3232816.0 261000.0 0.21 0.1488 0.7154 3629109 CBKinase1_018992 Cn1c(SCC(=O)Nc2ccc3ccccc3c2)nnc1c4cc5ccccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J15 compound treatment 3105728.0 134000.0 0.11 3453394.0 482000.0 0.38 0.3516 0.8784 3629110 CBKinase1_018993 COc1ccc(OC)c(c1)n2c(S)nnc2c3cc(n[nH]3)c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J16 compound treatment 3088153.0 117000.0 0.1 3249566.0 278000.0 0.22 0.2262 0.9336 3629111 CBKinase1_018994 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3cccs3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J17 compound treatment 3264877.0 294000.0 0.25 3125309.0 153000.0 0.12 0.2616 0.9472 3629112 CBKinase1_018995 COc1ccc(CNc2nc(nn2C(=O)c3ccco3)c4ccc(Cl)cc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J18 compound treatment 3247081.0 276000.0 0.23 3221095.0 249000.0 0.2 0.3049 0.9969 3629113 CBKinase1_018996 Cc1ccc(cc1)n2c(SCC(=O)Nc3sc4CCCCc4c3C#N)nnc2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J19 compound treatment 3361252.0 390000.0 0.33 3442528.0 471000.0 0.38 0.4978 0.9978 3629114 CBKinase1_018997 COC(=O)c1cc(C)sc1NC(=S)Nc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J20 compound treatment 2864178.0 -107000.0 -0.09 3181610.0 210000.0 0.17 0.0543 0.2857 3629115 CBKinase1_018998 COc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)ccc1NC(=O)c3cc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J21 mock treatment 2999445.0 28100.0 0.02 2768365.0 -203000.0 -0.16 -0.0979 -0.5974 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J22 mock treatment 2892452.0 -78900.0 -0.07 2854602.0 -117000.0 -0.09 -0.1131 -0.9862 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J23 compound treatment 2746783.0 -225000.0 -0.19 2634265.0 -338000.0 -0.27 -0.3242 -0.9852 3629116 CBKinase1_018999 COC(=O)c1ccc(C(=O)OC)c(NC(=O)Nc2cc(Cl)ccc2OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 J24 compound treatment 2526543.0 -445000.0 -0.38 2276459.0 -695000.0 -0.55 -0.6572 -0.9819 3629117 CBKinase1_019000 NC(=O)c1ccccc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K01 compound treatment 1439487.0 -1530000.0 -1.29 1876268.0 -1100000.0 -0.87 -1.5311 -0.9818 3629118 CBKinase1_019001 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3N4CCOCC4)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K02 compound treatment 2377799.0 -594000.0 -0.5 2582254.0 -390000.0 -0.31 -0.5736 -0.9736 3629119 CBKinase1_019002 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cccc4CCCCc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K03 compound treatment 3168883.0 198000.0 0.17 3134389.0 163000.0 0.13 0.2094 0.9923 1803432 CBKinase1_019003 CC(Sc1nnc(N)s1)C(=O)Nc2cccc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K04 compound treatment 3206580.0 235000.0 0.2 3239068.0 267000.0 0.21 0.2909 0.9994 3629120 CBKinase1_019004 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2ccc(I)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K05 compound treatment 3317603.0 346000.0 0.29 3007626.0 35800.0 0.03 0.2267 0.7725 3629121 CBKinase1_019005 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2ccc(Oc3ccccc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K06 compound treatment 3207307.0 236000.0 0.2 2593705.0 -378000.0 -0.3 -0.0724 -0.2004 3629122 CBKinase1_019006 Cc1ccc(C)c(c1)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K07 mock treatment 2976335.0 4990.0 0.0 3218287.0 246000.0 0.2 0.1419 0.7221 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K08 mock treatment 2981664.0 10300.0 0.01 3216359.0 245000.0 0.19 0.144 0.738 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K09 compound treatment 2777445.0 -194000.0 -0.16 3013172.0 41300.0 0.03 -0.0924 -0.5536 3629123 CBKinase1_019007 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2ccc(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K10 compound treatment 2794387.0 -177000.0 -0.15 2594404.0 -377000.0 -0.3 -0.3183 -0.9477 3629124 CBKinase1_019008 CC1(C)CC(=O)c2c(C1)oc3ccc(NS(=O)(=O)c4cccc5cccnc45)cc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K11 compound treatment 3031236.0 59900.0 0.05 3098851.0 127000.0 0.1 0.1073 0.9485 3629125 CBKinase1_019009 CCOC(=O)c1cc(sc1NC(=S)Nc2cnn(CC)c2C(=O)N)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K12 compound treatment 2630299.0 -341000.0 -0.29 2581489.0 -390000.0 -0.31 -0.4234 -0.9992 3629126 CBKinase1_019010 Cc1coc(C)c1C(=O)CC2(O)C(=O)N(Cc3ccccc3)c4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K13 compound treatment 2764122.0 -207000.0 -0.17 2720620.0 -251000.0 -0.2 -0.2652 -0.9977 3629127 CBKinase1_019011 Cc1cccc(C)c1NC(=O)COc2cc(O)c3c(=O)cc(oc3c2)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K14 compound treatment 2895028.0 -76300.0 -0.06 2522846.0 -449000.0 -0.36 -0.2986 -0.8211 3629128 CBKinase1_019012 COc1c(Cl)cc(cc1Cl)C(=O)Nc2sc3CC(C)CCc3c2C(=O)NC4CCS(=O)(=O)C4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K15 mock treatment 2799256.0 -172000.0 -0.15 2659810.0 -312000.0 -0.25 -0.2785 -0.9671 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K16 mock treatment 2886240.0 -85100.0 -0.07 2271076.0 -701000.0 -0.56 -0.4457 -0.7915 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K17 compound treatment 3144413.0 173000.0 0.15 2206231.0 -766000.0 -0.61 -0.3283 -0.5232 1562438 CBKinase1_019013 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccccc2OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K18 compound treatment 3016293.0 45000.0 0.04 2612404.0 -359000.0 -0.29 -0.1758 -0.6082 3629129 CBKinase1_019014 COc1ccc(cc1Cl)N(CC(=O)Nc2cccc([N+](=O)[O-])c2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K19 compound treatment 3440200.0 469000.0 0.4 2593706.0 -378000.0 -0.3 0.0665 0.1338 3629130 CBKinase1_019015 Cc1nn(CC(O)COc2ccc3cc(Br)ccc3c2)c(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K20 compound treatment 3195894.0 225000.0 0.19 2088818.0 -883000.0 -0.7 -0.3637 -0.4991 3629131 CBKinase1_019016 Cc1cccc(OCC(O)Cn2cnc3ccccc23)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K21 compound treatment 3209784.0 238000.0 0.2 2162872.0 -809000.0 -0.64 -0.3137 -0.4645 3629132 CBKinase1_019017 COc1cc(ccc1NC(=O)NCc2cccnc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K22 compound treatment 3082036.0 111000.0 0.09 2823408.0 -148000.0 -0.12 -0.0176 -0.117 3040107 CBKinase1_019018 CCN1CCOC(CC(=O)Nc2cccc(OC)c2)C1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K23 mock treatment 3034515.0 63200.0 0.05 2992764.0 20900.0 0.02 0.0495 0.886 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 K24 mock treatment 1947683.0 -1020000.0 -0.86 1986830.0 -985000.0 -0.79 -1.1657 -0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L01 compound treatment 2227835.0 -744000.0 -0.63 2171804.0 -800000.0 -0.64 -0.8944 -1.0 3629133 CBKinase1_019019 Cc1nnc(SCC(=O)Nc2ccc(Br)c(C)c2C)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L02 compound treatment 2744984.0 -226000.0 -0.19 2683566.0 -288000.0 -0.23 -0.2975 -0.9958 3629134 CBKinase1_019020 CCOC(=O)c1c(NC(=O)C2C3CC(C=C3)C2(C)C(=O)O)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L03 compound treatment 2974750.0 3410.0 0.0 2930625.0 -41200.0 -0.03 -0.0212 -0.6428 3629135 CBKinase1_019021 COC(=O)c1ccc(Cl)c(NC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L04 compound treatment 2866273.0 -105000.0 -0.09 2987677.0 15800.0 0.01 -0.0537 -0.6004 3629136 CBKinase1_019022 CCOC(=O)c1oc2c(C)c(O)ccc2c(=O)c1c3nncn3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L05 compound treatment 2921981.0 -49400.0 -0.04 2959789.0 -12100.0 -0.01 -0.0362 -0.848 3629137 CBKinase1_019023 CCOc1cc(ccc1Cl)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L06 compound treatment 2935296.0 -36000.0 -0.03 2818969.0 -153000.0 -0.12 -0.1077 -0.8573 3629138 CBKinase1_019024 [O-][N+](=O)c1cccc(NC(=O)CC2NCCNC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L07 mock treatment 3013713.0 42400.0 0.04 3209263.0 237000.0 0.19 0.1591 0.8261 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L08 mock treatment 3155872.0 185000.0 0.16 3103009.0 131000.0 0.1 0.184 0.9812 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L09 compound treatment 2819343.0 -152000.0 -0.13 3148127.0 176000.0 0.14 0.0087 0.0457 3629139 CBKinase1_019025 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2c(F)cccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L10 compound treatment 2946951.0 -24400.0 -0.02 3102221.0 130000.0 0.1 0.0589 0.5563 3629140 CBKinase1_019026 COc1ccc(NC(=O)Nc2nn(Cc3c(F)cccc3Cl)cc2Cl)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L11 compound treatment 2998048.0 26700.0 0.02 3267466.0 296000.0 0.24 0.1825 0.7712 3629141 CBKinase1_019027 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2cc(ccc2Cl)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L12 compound treatment 3154096.0 183000.0 0.15 2526963.0 -445000.0 -0.35 -0.1417 -0.3666 2068065 CBKinase1_019028 COc1ccccc1NC(=O)CC(N(C)C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L13 compound treatment 3018882.0 47500.0 0.04 3222511.0 251000.0 0.2 0.1696 0.8324 3629142 CBKinase1_019029 Clc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L14 compound treatment 3088868.0 118000.0 0.1 3015056.0 43200.0 0.03 0.0944 0.9 3629143 CBKinase1_019030 COc1ccc(C)cc1N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L15 mock treatment 3269275.0 298000.0 0.25 3300197.0 328000.0 0.26 0.3628 0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L16 mock treatment 3361359.0 390000.0 0.33 3249759.0 278000.0 0.22 0.3893 0.9815 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L17 compound treatment 3391500.0 420000.0 0.35 3086133.0 114000.0 0.09 0.315 0.8609 3629144 CBKinase1_019031 OC1(CC(=O)c2ccccc2[N+](=O)[O-])C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L18 compound treatment 3274603.0 303000.0 0.26 3058143.0 86300.0 0.07 0.2295 0.8665 3629145 CBKinase1_019032 COC(=O)c1cn(C(=O)C(C)Oc2ccc(Br)cc2)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L19 compound treatment 3655145.0 684000.0 0.58 2510756.0 -461000.0 -0.37 0.148 0.2164 3629146 CBKinase1_019033 COc1cc(ccc1NC(=S)NCc2ccco2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L20 compound treatment 3726605.0 755000.0 0.64 3390043.0 418000.0 0.33 0.6862 0.9543 3629147 CBKinase1_019034 Clc1cc(Cl)c(OCC(=O)Nc2nnc[nH]2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L21 compound treatment 3670812.0 699000.0 0.59 3267217.0 295000.0 0.24 0.5837 0.9188 3629148 CBKinase1_019035 CCOc1ccccc1NC(=O)CC2NCCNC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L22 compound treatment 3568426.0 597000.0 0.5 3124086.0 152000.0 0.12 0.4419 0.8531 3629149 CBKinase1_019036 CC(Oc1ccc(Br)cc1)C(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L23 mock treatment 3375410.0 404000.0 0.34 3055544.0 83700.0 0.07 0.2882 0.8298 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 L24 mock treatment 2791490.0 -180000.0 -0.15 2683066.0 -289000.0 -0.23 -0.27 -0.9795 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M01 compound treatment 2315397.0 -656000.0 -0.55 2025945.0 -946000.0 -0.75 -0.9243 -0.9884 1413832 CBKinase1_019037 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M02 compound treatment 2514199.0 -457000.0 -0.39 2409113.0 -563000.0 -0.45 -0.5898 -0.9972 3629150 CBKinase1_019038 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cccc(Br)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M03 compound treatment 2812382.0 -159000.0 -0.13 3229355.0 258000.0 0.21 0.0503 0.2053 3629151 CBKinase1_019039 COC(=O)c1ccc(Cl)c(NC(=O)CN(c2ccccc2Br)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M04 compound treatment 2834229.0 -137000.0 -0.12 3196692.0 225000.0 0.18 0.0449 0.2107 3629152 CBKinase1_019040 COc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M05 compound treatment 3420749.0 449000.0 0.38 3192715.0 221000.0 0.18 0.3925 0.9392 3629153 CBKinase1_019041 CSc1ccccc1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M06 compound treatment 3419863.0 449000.0 0.38 3522259.0 550000.0 0.44 0.5777 0.9973 3629154 CBKinase1_019042 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccc(Cl)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M07 compound treatment 3488087.0 517000.0 0.44 3105699.0 134000.0 0.11 0.3836 0.8549 3629155 CBKinase1_019043 O=c1[nH]c2ccc(cc2[nH]1)S(=O)(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M08 compound treatment 3483544.0 512000.0 0.43 3249001.0 277000.0 0.22 0.4617 0.9515 1153019 CBKinase1_019044 CCOC(=O)c1c(NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N3CCOCC3)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M09 mock treatment 3790109.0 819000.0 0.69 3751575.0 780000.0 0.62 0.9278 0.9986 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M10 mock treatment 4136909.0 1170000.0 0.98 3563365.0 592000.0 0.47 1.0286 0.9433 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M11 compound treatment 3773926.0 803000.0 0.68 3263387.0 292000.0 0.23 0.643 0.8984 3629156 CBKinase1_019045 COC(=O)c1cc(sc1NC(=S)Nc2cn(C)nc2C)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M12 compound treatment 3949068.0 978000.0 0.82 3687872.0 716000.0 0.57 0.9867 0.9838 2067981 CBKinase1_019046 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)NC2CCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M13 mock treatment 3584756.0 613000.0 0.52 3631329.0 659000.0 0.53 0.7375 1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M14 mock treatment 3935026.0 964000.0 0.81 3232049.0 260000.0 0.21 0.7214 0.86 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M15 compound treatment 3572062.0 601000.0 0.51 3624100.0 652000.0 0.52 0.7259 0.9999 3629157 CBKinase1_019047 Cc1ccc2nsnc2c1S(=O)(=O)N3CCN(CCc4ccccc4)CC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M16 compound treatment 4113577.0 1140000.0 0.96 3671568.0 700000.0 0.56 1.0756 0.9662 3629158 CBKinase1_019048 Fc1ccccc1NC(=O)CSc2nnc(o2)c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M17 compound treatment 4134384.0 1160000.0 0.98 3611050.0 639000.0 0.51 1.0539 0.9534 3629159 CBKinase1_019049 COc1ccc(NC(=O)CC(N(C)C)C(=O)O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M18 compound treatment 4462049.0 1490000.0 1.26 3576220.0 604000.0 0.48 1.2297 0.9133 3629160 CBKinase1_019050 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M19 compound treatment 3079683.0 108000.0 0.09 2887313.0 -84500.0 -0.07 0.017 0.1495 3629161 CBKinase1_019051 Cc1cc(O)nc(SCC(=O)Nc2ccnc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M20 compound treatment 4103161.0 1130000.0 0.95 2762404.0 -209000.0 -0.17 0.557 0.5747 3629162 CBKinase1_019052 Cc1ccc(Cl)cc1N(CC(=O)Nc2cccc([N+](=O)[O-])c2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M21 compound treatment 2384840.0 -587000.0 -0.49 3501234.0 529000.0 0.42 -0.0515 -0.0791 2068014 CBKinase1_019053 NC(CC(=O)Nc1ccc(Cl)cc1)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M22 compound treatment 4391960.0 1420000.0 1.2 3180973.0 209000.0 0.17 0.9652 0.7978 3629163 CBKinase1_019054 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nnc[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M23 compound treatment 3717835.0 746000.0 0.63 3205157.0 233000.0 0.19 0.5767 0.8784 3629164 CBKinase1_019055 COc1ccccc1CNC(=O)c2ccccc2N(C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 M24 compound treatment 2493720.0 -478000.0 -0.4 2466724.0 -505000.0 -0.4 -0.5696 -1.0 3629165 CBKinase1_019056 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2cc(Cl)ccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N01 compound treatment 2452102.0 -519000.0 -0.44 2982016.0 10200.0 0.01 -0.304 -0.6939 3629166 CBKinase1_019057 Cc1nc2ccc(F)cc2cc1C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N02 compound treatment 2675832.0 -296000.0 -0.25 2412083.0 -560000.0 -0.45 -0.4917 -0.9622 3629167 CBKinase1_019058 [O-][N+](=O)c1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N03 compound treatment 2787811.0 -184000.0 -0.15 2757962.0 -214000.0 -0.17 -0.23 -0.9988 3629168 CBKinase1_019059 COC(=O)c1ccccc1NC(=O)Nc2cnn(Cc3ccc(Cl)cc3Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N04 compound treatment 3065523.0 94200.0 0.08 2760355.0 -211000.0 -0.17 -0.063 -0.3382 3629169 CBKinase1_019060 Ic1ccc(NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N05 compound treatment 4317531.0 1350000.0 1.14 3213061.0 241000.0 0.19 0.9389 0.8152 3629170 CBKinase1_019061 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N06 compound treatment 3775615.0 804000.0 0.68 3448050.0 476000.0 0.38 0.7481 0.9623 3629171 CBKinase1_019062 COc1ccc(cc1OC)C(=O)CCC(=O)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N07 compound treatment 3461498.0 490000.0 0.41 3163616.0 192000.0 0.15 0.4004 0.9084 3629172 CBKinase1_019063 Cc1cc(C)cc(COc2ccc3c(C)c(CCC(=O)O)c(=O)oc3c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N08 compound treatment 3704592.0 733000.0 0.62 3293795.0 322000.0 0.26 0.6188 0.9241 3629173 CBKinase1_019064 CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2Br)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N09 mock treatment 4012332.0 1040000.0 0.88 3281478.0 310000.0 0.25 0.7954 0.8721 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N10 mock treatment 3975349.0 1000000.0 0.85 3329549.0 358000.0 0.29 0.8004 0.8958 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N11 compound treatment 3624793.0 653000.0 0.55 3543921.0 572000.0 0.46 0.7122 0.9956 3629174 CBKinase1_019065 COC(=O)c1cc(NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)C)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N12 compound treatment 3661745.0 690000.0 0.58 3430538.0 459000.0 0.37 0.6703 0.9748 3629175 CBKinase1_019066 Cc1cc(CNC(=S)Nc2cccc(c2)[N+](=O)[O-])nn1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N13 mock treatment 3833893.0 863000.0 0.73 3313422.0 342000.0 0.27 0.707 0.9101 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N14 mock treatment 3559591.0 588000.0 0.5 3497044.0 525000.0 0.42 0.6469 0.9964 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N15 compound treatment 3511896.0 541000.0 0.46 3651672.0 680000.0 0.54 0.7056 0.9963 3629176 CBKinase1_019067 CCOC(=O)c1c(NC(=S)N(C)Cc2c(C)nn(C)c2C)sc3CCCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N16 compound treatment 4056047.0 1080000.0 0.91 3611379.0 640000.0 0.51 1.0074 0.9619 3629177 CBKinase1_019068 COC(=O)c1c(NC(=S)Nc2cccc(Cn3cc(Cl)cn3)c2)sc4CCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N17 compound treatment 4274571.0 1300000.0 1.1 3497264.0 525000.0 0.42 1.0734 0.9125 3629178 CBKinase1_019069 Clc1ccc(Cl)c(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N18 compound treatment 3518974.0 548000.0 0.46 2890772.0 -81100.0 -0.06 0.2809 0.6023 3629179 CBKinase1_019070 OC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N19 compound treatment 2582449.0 -389000.0 -0.33 2663854.0 -308000.0 -0.25 -0.4055 -0.9898 3629180 CBKinase1_019071 O=S(=O)(Nc1ncccn1)c2ccc(NC(=S)Nc3ccc4CCCc4c3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N20 compound treatment 4150534.0 1180000.0 0.99 2830651.0 -141000.0 -0.11 0.6237 0.6231 3629181 CBKinase1_019072 OC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N21 compound treatment 2123273.0 -848000.0 -0.72 2900214.0 -71600.0 -0.06 -0.5462 -0.7611 3629182 CBKinase1_019073 CCOC(=O)c1cc(NC(=O)CSc2nnc(C)s2)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N22 compound treatment 3469100.0 498000.0 0.42 3225935.0 254000.0 0.2 0.4401 0.9441 3629183 CBKinase1_019074 CN(CC(=O)Nc1c(C)cc(C)cc1C)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N23 compound treatment 3581290.0 610000.0 0.51 3354721.0 383000.0 0.31 0.5796 0.9689 3629184 CBKinase1_019075 Clc1cnn(CCNC(=O)Nc2cccc(Cl)c2Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 N24 compound treatment 3162182.0 191000.0 0.16 2746872.0 -225000.0 -0.18 -0.013 -0.0538 3629185 CBKinase1_019076 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccc(Nc4ccccc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O01 compound treatment 2313073.0 -658000.0 -0.56 2053365.0 -918000.0 -0.73 -0.9103 -0.9907 3629186 CBKinase1_019077 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)CC(CN2CCOCC2)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O02 compound treatment 2438985.0 -532000.0 -0.45 3377972.0 406000.0 0.32 -0.0886 -0.1601 3629187 CBKinase1_019078 Cc1c(Cl)c(nn1CCCNC(=O)Nc2cccc(c2)[N+](=O)[O-])C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O03 compound treatment 2987042.0 15700.0 0.01 3796562.0 825000.0 0.66 0.4742 0.7212 3629188 CBKinase1_019079 CCS(=O)(=O)n1nc(nc1NCc2ccco2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O04 compound treatment 3347665.0 376000.0 0.32 3219139.0 247000.0 0.2 0.3638 0.9737 3629189 CBKinase1_019080 O=C(CC1NCCNC1=O)Nc2ccc3OCCOc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O05 compound treatment 3191177.0 220000.0 0.19 3290577.0 319000.0 0.25 0.3108 0.988 3629190 CBKinase1_019081 CCOC(=O)c1sc(NC(=S)Nc2cnccn2)c(C(=O)OCC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O06 compound treatment 3185571.0 214000.0 0.18 3062214.0 90400.0 0.07 0.1787 0.9187 3629191 CBKinase1_019082 COC(=O)c1cccc(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O07 compound treatment 3480880.0 510000.0 0.43 3148452.0 177000.0 0.14 0.4034 0.8921 1433247 CBKinase1_019083 COc1ccc(CCNC(=S)Nc2cc3oc4ccccc4c3cc2OC)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O08 compound treatment 3481451.0 510000.0 0.43 3099687.0 128000.0 0.1 0.3763 0.851 3629192 CBKinase1_019084 COC(=O)c1ccc(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O09 compound treatment 3524228.0 553000.0 0.47 3532600.0 561000.0 0.45 0.6458 0.9998 3629193 CBKinase1_019085 Cc1ccccc1NC(=O)CC2NCCNC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O10 compound treatment 3262710.0 291000.0 0.25 2950978.0 -20900.0 -0.02 0.162 0.6577 3629194 CBKinase1_019086 CC(Oc1ccc2c(C)c(CC(=O)O)c(=O)oc2c1C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O11 mock treatment 3675424.0 704000.0 0.59 3178232.0 206000.0 0.16 0.5363 0.8702 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O12 mock treatment 3621618.0 650000.0 0.55 3379721.0 408000.0 0.33 0.6177 0.9688 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O13 compound treatment 4001711.0 1030000.0 0.87 3506265.0 534000.0 0.43 0.9158 0.9461 3629195 CBKinase1_019087 Oc1ccccc1c2nnc(SCc3ccccc3C#N)n2CC=C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O14 compound treatment 4224574.0 1250000.0 1.06 3351432.0 380000.0 0.3 0.9614 0.8744 3629196 CBKinase1_019088 COC(=O)c1cc(sc1NC(=S)NCCn2cc(Br)cn2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O15 compound treatment 3910444.0 939000.0 0.79 3408743.0 437000.0 0.35 0.8064 0.9319 3629197 CBKinase1_019089 Cc1nc(SCc2cccc(c2)C(=O)O)nc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O16 compound treatment 4174902.0 1200000.0 1.02 3532687.0 561000.0 0.45 1.0339 0.9321 3629198 CBKinase1_019090 O=C(CSc1nnc([nH]1)c2ccco2)Nc3sc4CCCCc4c3C(=O)Nc5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O17 compound treatment 4420002.0 1450000.0 1.22 3833359.0 862000.0 0.69 1.3496 0.9628 3629199 CBKinase1_019091 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O18 compound treatment 4260075.0 1290000.0 1.09 3504477.0 533000.0 0.42 1.0688 0.9159 3629200 CBKinase1_019092 CC(C)(C)Nc1nc(SCC(=O)N)nc(n1)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O19 compound treatment 4691954.0 1720000.0 1.45 2500936.0 -471000.0 -0.38 0.7608 0.5075 3629201 CBKinase1_019093 COc1ccccc1n2nnnc2SCC(=O)Nc3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O20 compound treatment 4688392.0 1720000.0 1.45 3283187.0 311000.0 0.25 1.1996 0.8164 3629202 CBKinase1_019094 Cc1cc(ccc1NC(=O)CSc2nnc(c3cc4ccccc4o3)n2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O21 compound treatment 3316938.0 346000.0 0.29 2986246.0 14400.0 0.01 0.2142 0.7344 3629203 CBKinase1_019095 CC1CN(CC(C)O1)C(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O22 compound treatment 3343614.0 372000.0 0.31 3220497.0 249000.0 0.2 0.3622 0.9754 3629204 CBKinase1_019096 COc1ccc(cc1OC)N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O23 compound treatment 3271526.0 300000.0 0.25 3413135.0 441000.0 0.35 0.4278 0.987 3629205 CBKinase1_019097 COc1ccc(Cl)cc1N(CC(=O)Nc2ccccc2SC)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 O24 compound treatment 2676878.0 -294000.0 -0.25 2594372.0 -377000.0 -0.3 -0.3884 -0.9955 3629206 CBKinase1_019098 O=C(c1cccs1)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P01 compound treatment 2235118.0 -736000.0 -0.62 2947372.0 -24500.0 -0.02 -0.4529 -0.729 3629207 CBKinase1_019099 COC(=O)c1c(NC(=S)Nc2ccn(C)n2)sc(C)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P02 compound treatment 2265820.0 -706000.0 -0.6 3434828.0 463000.0 0.37 -0.1599 -0.2283 3629208 CBKinase1_019100 Oc1ccc(cc1)n2nnnc2SCC(=O)Nc3ccc(N4CCOCC4)c(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P03 compound treatment 1961152.0 -1010000.0 -0.85 3268807.0 297000.0 0.24 -0.4352 -0.4921 3629209 CBKinase1_019101 COc1ccc(NC(=S)Nc2cnn(C)c2C(=O)N)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P04 compound treatment 3457671.0 486000.0 0.41 1948470.0 -1020000.0 -0.82 -0.2867 -0.314 3629210 CBKinase1_019102 CCOc1ccccc1NC(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P05 compound treatment 3760902.0 790000.0 0.67 2508503.0 -463000.0 -0.37 0.2098 0.2755 1984402 CBKinase1_019103 CC(=O)n1nc(nc1NCc2ccco2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P06 compound treatment 2952421.0 -18900.0 -0.02 2275734.0 -696000.0 -0.55 -0.4036 -0.7271 3629211 CBKinase1_019104 COC(=O)c1cc(C)sc1NC(=S)NCCc2ccccc2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P07 compound treatment 2623670.0 -348000.0 -0.29 2295436.0 -676000.0 -0.54 -0.5886 -0.959 3629212 CBKinase1_019105 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3c(C)cc(C)cc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P08 compound treatment 2896147.0 -75200.0 -0.06 2423810.0 -548000.0 -0.44 -0.3537 -0.8014 3629213 CBKinase1_019106 Cc1nc(C)n(CC(O)COc2ccc3ccccc3c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P09 compound treatment 2525804.0 -446000.0 -0.38 2563566.0 -408000.0 -0.33 -0.4958 -0.9974 3629214 CBKinase1_019107 Cc1ccc(C)c(c1)S(=O)(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P10 compound treatment 2122350.0 -849000.0 -0.72 2988878.0 17000.0 0.01 -0.4968 -0.6936 3629215 CBKinase1_019108 Cc1c(CCC(=O)O)c(=O)oc2cc(O)c(Cl)cc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P11 mock treatment 2688864.0 -282000.0 -0.24 2904965.0 -66900.0 -0.05 -0.2062 -0.8444 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P12 mock treatment 2735570.0 -236000.0 -0.2 2658311.0 -314000.0 -0.25 -0.3173 -0.9936 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P13 compound treatment 3125521.0 154000.0 0.13 2751877.0 -220000.0 -0.18 -0.032 -0.1467 3629216 CBKinase1_019109 OC1(CC(=O)c2cccc(c2)n3cccc3)C(=O)Nc4ccccc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P14 compound treatment 2999572.0 28200.0 0.02 2958347.0 -13500.0 -0.01 0.0092 0.3532 3629217 CBKinase1_019110 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCN(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P15 compound treatment 3181820.0 210000.0 0.18 3034131.0 62300.0 0.05 0.1606 0.8714 3629218 CBKinase1_019111 CCn1cc(C(C)NC(=S)Nc2cccc(c2)[N+](=O)[O-])c(C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P16 compound treatment 3686705.0 715000.0 0.6 3373105.0 401000.0 0.32 0.6528 0.9559 3629219 CBKinase1_019112 Cc1ccc(NC(=O)Cc2nnc(S)n2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P17 compound treatment 3072721.0 101000.0 0.09 3026494.0 54600.0 0.04 0.0913 0.951 3629220 CBKinase1_019113 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P18 compound treatment 3285320.0 314000.0 0.26 2908719.0 -63100.0 -0.05 0.1517 0.5627 3629221 CBKinase1_019114 CN(CC(=O)Nc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P19 compound treatment 3583317.0 612000.0 0.52 3397565.0 426000.0 0.34 0.6049 0.9793 3629222 CBKinase1_019115 COc1ccc(CCNC(=S)n2cc(C)cn2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P20 compound treatment 3801570.0 830000.0 0.7 3482363.0 511000.0 0.41 0.7829 0.9666 3629223 CBKinase1_019116 COc1ccc(cc1S(=O)(=O)Nc2cc(C)on2)C(=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P21 compound treatment 4004135.0 1030000.0 0.87 3415311.0 443000.0 0.35 0.8659 0.9211 3629224 CBKinase1_019117 Clc1cc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)ccc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P22 compound treatment 2936088.0 -35300.0 -0.03 3339917.0 368000.0 0.29 0.1864 0.6322 3629225 CBKinase1_019118 OC(=O)c1ccccc1c2ccccc2C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P23 compound treatment 3252973.0 282000.0 0.24 3076126.0 104000.0 0.08 0.2267 0.901 3629226 CBKinase1_019119 CC(C)(C)Nc1nc(SCC(=O)Nc2ccccc2)nc(n1)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2383 P24 compound treatment 2841912.0 -129000.0 -0.11 2556726.0 -415000.0 -0.33 -0.3112 -0.8931 3629227 CBKinase1_019120 Cc1c(NC(=O)COc2ccc(Br)cc2)cccc1C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A01 compound treatment 2348167.0 -726000.0 -0.61 2678448.0 -497000.0 -0.4 -0.7136 -0.9778 3629228 CBKinase1_019121 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2ccccc2N(C)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A02 compound treatment 2550955.0 -524000.0 -0.44 3731753.0 556000.0 0.44 0.001 0.0016 3629229 CBKinase1_019122 Cc1c(NC(=O)CN(c2ccccc2F)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A03 compound treatment 3288679.0 214000.0 0.18 3113056.0 -62800.0 -0.05 0.0923 0.4925 3629230 CBKinase1_019123 COc1ccc(Cl)cc1NC(=O)CC(N2CCNCC2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A04 compound treatment 2652209.0 -422000.0 -0.36 3798334.0 622000.0 0.5 0.0989 0.162 3629231 CBKinase1_019124 O=C(CC1N(C2CCCCC2NC1=O)C(=O)Nc3ccccc3)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A05 compound treatment 3892678.0 818000.0 0.69 2880013.0 -296000.0 -0.24 0.3212 0.4405 3629232 CBKinase1_019125 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A06 compound treatment 3048019.0 -26500.0 -0.02 2749429.0 -426000.0 -0.34 -0.2561 -0.7519 3629233 CBKinase1_019126 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1F)c2ccc(Cl)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A07 compound treatment 2945769.0 -129000.0 -0.11 2705836.0 -470000.0 -0.37 -0.3417 -0.876 3629234 CBKinase1_019127 COc1ccc(Cn2c(nc3ccccc23)c4nonc4NC(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A08 compound treatment 2809358.0 -265000.0 -0.22 2918390.0 -258000.0 -0.21 -0.3033 -0.9991 3629235 CBKinase1_019128 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A09 compound treatment 3091427.0 17000.0 0.01 3337811.0 162000.0 0.13 0.1014 0.7807 3629236 CBKinase1_019129 CC(=O)c1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A10 compound treatment 3034239.0 -40200.0 -0.03 3013042.0 -163000.0 -0.13 -0.1158 -0.863 3629237 CBKinase1_019130 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cc(ccc3C)[N+](=O)[O-])n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A11 compound treatment 3371099.0 297000.0 0.25 3592805.0 417000.0 0.33 0.4119 0.9902 3629238 CBKinase1_019131 COc1ccc(cc1Cl)N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A12 compound treatment 3305278.0 231000.0 0.19 3523940.0 348000.0 0.28 0.3338 0.985 3629239 CBKinase1_019132 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3cccc(F)c3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A13 mock treatment 3270698.0 196000.0 0.17 3403337.0 227000.0 0.18 0.2452 0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A14 mock treatment 3110646.0 36200.0 0.03 3389528.0 214000.0 0.17 0.142 0.8207 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A15 compound treatment 3125884.0 51400.0 0.04 2978630.0 -197000.0 -0.16 -0.0805 -0.4937 3629240 CBKinase1_019133 COC(=O)c1cc(NC(=O)CSc2nnc(C)s2)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A16 compound treatment 3469127.0 395000.0 0.33 3554910.0 379000.0 0.3 0.449 0.9988 3629241 CBKinase1_019134 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Nc2c(C)cc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A17 compound treatment 2988003.0 -86500.0 -0.07 3611126.0 435000.0 0.35 0.1937 0.5465 3629242 CBKinase1_019135 CC(Sc1nc(O)c(c2ccccc2)c(=O)[nH]1)C(=O)Nc3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A18 compound treatment 3262655.0 188000.0 0.16 3596831.0 421000.0 0.34 0.3495 0.9416 3629243 CBKinase1_019136 COc1cccc(c1)N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A19 compound treatment 3569329.0 495000.0 0.42 2870474.0 -305000.0 -0.24 0.123 0.2546 3629244 CBKinase1_019137 CSc1ccccc1NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A20 compound treatment 3506367.0 432000.0 0.36 3747058.0 571000.0 0.46 0.5795 0.9939 3629245 CBKinase1_019138 COc1ccc(cc1OC)N(CC(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A21 compound treatment 3222902.0 148000.0 0.13 3548870.0 373000.0 0.3 0.2987 0.9261 3629246 CBKinase1_019139 Clc1cccc(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A22 compound treatment 3163826.0 89400.0 0.08 3137995.0 -37900.0 -0.03 0.0319 0.3932 3629247 CBKinase1_019140 CC(C)c1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A23 compound treatment 3304305.0 230000.0 0.19 3282363.0 106000.0 0.08 0.1971 0.9313 3629248 CBKinase1_019141 O=C(COc1ccc(cc1)c2ccc(C#N)cc2)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 A24 compound treatment 3058156.0 -16300.0 -0.01 2933833.0 -242000.0 -0.19 -0.1462 -0.7556 3629249 CBKinase1_019142 COc1cc(ccc1NC(=S)Nc2cccc(Cn3nc(C)c(Br)c3C)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B01 compound treatment 2921486.0 -153000.0 -0.13 2781275.0 -395000.0 -0.31 -0.3137 -0.9226 3629250 CBKinase1_019143 CC(Oc1ccc(Br)cc1)c2nc(no2)c3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B02 compound treatment 3933253.0 859000.0 0.72 3843549.0 668000.0 0.53 0.8885 0.9885 3629251 CBKinase1_019144 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B03 compound treatment 3571808.0 497000.0 0.42 3422773.0 247000.0 0.2 0.4358 0.9405 3629252 CBKinase1_019145 COc1cc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])cc(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B04 compound treatment 4977450.0 1900000.0 1.61 3542625.0 367000.0 0.29 1.3417 0.8223 3629253 CBKinase1_019146 COC(=O)c1cc(C)sc1NC(=S)Nc2ncn(Cc3ccc(F)cc3Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B05 compound treatment 5285122.0 2210000.0 1.86 4947138.0 1770000.0 1.41 2.3168 0.9906 3629254 CBKinase1_019147 COC(=O)c1cccc(COC(=O)c2ccc(NC(=O)c3ccccc3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B06 compound treatment 3563244.0 489000.0 0.41 4120194.0 944000.0 0.75 0.8237 0.9599 3629255 CBKinase1_019148 COC(=O)c1cccc(NC(=O)COc2ccc(OC)cc2)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B07 compound treatment 3326039.0 252000.0 0.21 3831067.0 655000.0 0.52 0.5193 0.9213 3629256 CBKinase1_019149 CC(C)c1ccccc1NC(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B08 compound treatment 4471787.0 1400000.0 1.18 4571995.0 1400000.0 1.11 1.6202 0.9996 3629257 CBKinase1_019150 [O-][N+](=O)c1cccc(NC(=O)Nc2nn(Cc3ccc(Cl)c(Cl)c3)cc2Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B09 compound treatment 3417091.0 343000.0 0.29 3909950.0 734000.0 0.59 0.6181 0.9471 3629258 CBKinase1_019151 Cc1c(NC(=O)COc2ccccc2Cl)cccc1C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B10 compound treatment 3669117.0 595000.0 0.5 3869493.0 694000.0 0.55 0.7456 0.9988 3629259 CBKinase1_019152 OC(=O)C(CC(=O)Nc1cccc(c1)[N+](=O)[O-])N2CCCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B11 compound treatment 4014288.0 940000.0 0.79 3814665.0 639000.0 0.51 0.9205 0.9771 3629260 CBKinase1_019153 O=C(NCc1ccco1)c2ccc3C(=O)N(Cc4cccnc4)C(=O)c3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B12 compound treatment 4364944.0 1290000.0 1.09 4355451.0 1180000.0 0.94 1.4345 0.9973 3629261 CBKinase1_019154 COc1ccc(CCNC(=O)C(=O)Nc2ccc(cc2)C(C)(C)C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B13 mock treatment 4309625.0 1240000.0 1.04 4417500.0 1240000.0 0.99 1.4365 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B14 mock treatment 4367665.0 1290000.0 1.09 4547870.0 1370000.0 1.09 1.5445 1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B15 compound treatment 4166195.0 1090000.0 0.92 4680076.0 1500000.0 1.2 1.4989 0.9915 3211646 CBKinase1_019155 CCOC(=O)COc1ccc(cc1)c2nnn[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B16 compound treatment 4136737.0 1060000.0 0.9 4460231.0 1280000.0 1.02 1.3574 0.9978 3629262 CBKinase1_019156 FC(F)(F)Oc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B17 compound treatment 3781096.0 707000.0 0.6 4045571.0 870000.0 0.69 0.9116 0.9972 3629263 CBKinase1_019157 COC(=O)c1c(NC(=S)Nc2ccn(C)n2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B18 compound treatment 4128034.0 1050000.0 0.89 4265926.0 1090000.0 0.87 1.2427 0.9999 3629264 CBKinase1_019158 CCOC(=O)c1c(NC(=S)Nc2nc(C)cc(C)n2)sc3CCCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B19 compound treatment 4283224.0 1210000.0 1.02 4179642.0 1000000.0 0.8 1.2867 0.9928 3629265 CBKinase1_019159 COC(=O)c1cc(sc1NC(=S)NC(C)c2cc(OC)ccc2OC)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B20 compound treatment 4194457.0 1120000.0 0.94 4389335.0 1210000.0 0.97 1.3519 0.9999 3629266 CBKinase1_019160 COC(=O)c1c(NC(=S)NCc2ccccn2)sc(C)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B21 compound treatment 4254406.0 1180000.0 1.0 4313699.0 1140000.0 0.91 1.345 0.9989 3629267 CBKinase1_019161 CCn1cc(CNC(=S)Nc2cc(OC)ccc2OC)cn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B22 compound treatment 4742839.0 1670000.0 1.41 4205590.0 1030000.0 0.82 1.5754 0.967 3629268 CBKinase1_019162 O=C(C1c2ccccc2Oc3ccccc13)N(CCC#N)CCC#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B23 compound treatment 3898103.0 824000.0 0.69 3628927.0 453000.0 0.36 0.7466 0.9535 3629269 CBKinase1_019163 CCOC(=O)c1c(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 B24 compound treatment 3314091.0 240000.0 0.2 3317844.0 142000.0 0.11 0.2229 0.9624 3629270 CBKinase1_019164 Cc1cc(ccc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C01 compound treatment 3076866.0 2390.0 0.0 2535638.0 -640000.0 -0.51 -0.3594 -0.7043 3629271 CBKinase1_019165 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C02 compound treatment 2652918.0 -422000.0 -0.36 3636255.0 460000.0 0.37 0.008 0.0157 3629272 CBKinase1_019166 Cc1ccc(cc1NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C03 compound treatment 2856129.0 -218000.0 -0.18 2980999.0 -195000.0 -0.16 -0.2401 -0.9964 3629273 CBKinase1_019167 COc1cccc(Cn2cc(NC(=O)Nc3ccc(F)cc3F)cn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C04 compound treatment 3218341.0 144000.0 0.12 3666461.0 491000.0 0.39 0.3623 0.8849 2068000 CBKinase1_019168 OC(=O)C(CC(=O)Nc1ccccc1)N2CCCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C05 compound treatment 3254388.0 180000.0 0.15 3460958.0 285000.0 0.23 0.268 0.9808 3629274 CBKinase1_019169 COc1cc(ccc1NC(=S)Nc2cccc(Cn3cc(Cl)cn3)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C06 compound treatment 2773500.0 -301000.0 -0.25 2855079.0 -321000.0 -0.26 -0.3603 -1.0 3629275 CBKinase1_019170 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C07 compound treatment 2653590.0 -421000.0 -0.36 3284023.0 108000.0 0.09 -0.1901 -0.5204 3629276 CBKinase1_019171 O=C(N(CCC#N)CCC#N)c1ccccc1Oc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C08 compound treatment 2970872.0 -104000.0 -0.09 3055130.0 -121000.0 -0.1 -0.1299 -0.9988 3629277 CBKinase1_019172 CC(C)Cc1nnc(SC(C)C(=O)Nc2cccc(Cl)c2)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C09 compound treatment 2951054.0 -123000.0 -0.1 3201586.0 25700.0 0.02 -0.0591 -0.5574 3629278 CBKinase1_019173 COC(=O)c1c(NC(=S)Nc2cn(C)nc2C(=O)N)sc3CCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C10 compound treatment 2821221.0 -253000.0 -0.21 3326056.0 150000.0 0.12 -0.0664 -0.2713 3629279 CBKinase1_019174 CCOC(=O)c1c(NC(=O)c2ccccc2N(C)S(=O)(=O)C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C11 mock treatment 2960573.0 -114000.0 -0.1 3086245.0 -89700.0 -0.07 -0.1185 -0.9894 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C12 mock treatment 3093218.0 18700.0 0.02 3360192.0 184000.0 0.15 0.115 0.7787 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C13 compound treatment 3175643.0 101000.0 0.09 3806796.0 631000.0 0.5 0.4159 0.8154 3629280 CBKinase1_019175 COC(=O)c1c(NC(=S)NCCn2cc(Br)cn2)sc3CC(C)CCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C14 compound treatment 2829610.0 -245000.0 -0.21 3152515.0 -23400.0 -0.02 -0.1592 -0.7678 3629281 CBKinase1_019176 COc1cc(C)c(cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C15 mock treatment 3074327.0 -147.0 0.0 3341502.0 166000.0 0.13 0.0932 0.7064 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C16 mock treatment 3045859.0 -28600.0 -0.02 3397002.0 221000.0 0.18 0.1075 0.6046 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C17 compound treatment 3081543.0 7070.0 0.01 3374166.0 198000.0 0.16 0.116 0.7333 3629282 CBKinase1_019177 Cc1cc(NC(=O)C(=O)NCCCn2ccnc2)ccc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C18 compound treatment 3055726.0 -18700.0 -0.02 3366370.0 190000.0 0.15 0.0962 0.63 3629283 CBKinase1_019178 CN(c1ccccc1C(=O)NCc2ccco2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C19 compound treatment 3269354.0 195000.0 0.16 3034231.0 -142000.0 -0.11 0.0364 0.1825 3629284 CBKinase1_019179 COc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C20 compound treatment 3334914.0 260000.0 0.22 3284277.0 108000.0 0.09 0.2164 0.9168 3629285 CBKinase1_019180 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C21 compound treatment 3351089.0 277000.0 0.23 3248096.0 72200.0 0.06 0.2057 0.8558 3629286 CBKinase1_019181 Cc1nn(C)c(C)c1NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C22 compound treatment 3106533.0 32100.0 0.03 2996800.0 -179000.0 -0.14 -0.0818 -0.5631 3629287 CBKinase1_019182 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2cccc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C23 compound treatment 3014925.0 -59500.0 -0.05 2560134.0 -616000.0 -0.49 -0.3826 -0.7754 3629288 CBKinase1_019183 CC(C)CNc1nc(Oc2ccc(O)nn2)nc(n1)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 C24 compound treatment 2606296.0 -468000.0 -0.39 2479992.0 -696000.0 -0.55 -0.6715 -0.9861 3629289 CBKinase1_019184 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Cn2nnc(n2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D01 compound treatment 2926496.0 -148000.0 -0.12 2422631.0 -753000.0 -0.6 -0.5128 -0.8362 3629290 CBKinase1_019185 CS(=O)(=O)CCC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D02 compound treatment 3329689.0 255000.0 0.22 2817078.0 -359000.0 -0.29 -0.05 -0.1397 3629291 CBKinase1_019186 COc1cc(cc(Br)c1O)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D03 compound treatment 3241178.0 167000.0 0.14 2748222.0 -428000.0 -0.34 -0.1416 -0.384 3629292 CBKinase1_019187 Oc1nc2ccccc2nc1CCC(=O)OCc3c(F)cccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D04 compound treatment 3517065.0 443000.0 0.37 2839780.0 -336000.0 -0.27 0.0745 0.1622 3629293 CBKinase1_019188 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2cccc(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D05 compound treatment 3574283.0 500000.0 0.42 3148649.0 -27300.0 -0.02 0.2827 0.6698 3629294 CBKinase1_019189 COc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)ccc1NC(=O)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D06 compound treatment 4000607.0 926000.0 0.78 3317881.0 142000.0 0.11 0.6324 0.8012 3629295 CBKinase1_019190 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Sc3nc[nH]n3)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D07 compound treatment 4078390.0 1000000.0 0.85 3644786.0 469000.0 0.37 0.863 0.9324 3629296 CBKinase1_019191 COc1cc2c(cc1NC(=O)C(C)Oc3ccc(Br)cc3)oc4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D08 compound treatment 4149150.0 1070000.0 0.91 4004158.0 828000.0 0.66 1.1078 0.9879 1641496 CBKinase1_019192 COc1ccc(CCNC(=S)N2CCN(CC2)c3ncccn3)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D09 compound treatment 4043295.0 969000.0 0.82 3854887.0 679000.0 0.54 0.9605 0.98 3629297 CBKinase1_019193 OC(=O)CCC(=O)Nc1ccc(NC(=O)c2cccs2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D10 compound treatment 4483124.0 1410000.0 1.19 3883317.0 707000.0 0.56 1.2389 0.942 3629298 CBKinase1_019194 Cn1nnnc1SCC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D11 mock treatment 4417985.0 1340000.0 1.13 4027232.0 851000.0 0.68 1.2811 0.9699 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D12 mock treatment 4449748.0 1380000.0 1.16 3444516.0 269000.0 0.21 0.9717 0.8237 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D13 compound treatment 4320397.0 1250000.0 1.05 3467889.0 292000.0 0.23 0.9077 0.8433 3629299 CBKinase1_019195 COc1ccc(CCNC(=O)c2cc3cc(F)ccc3nc2C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D14 compound treatment 4128349.0 1050000.0 0.89 3713553.0 538000.0 0.43 0.9316 0.944 3629300 CBKinase1_019196 CCCOc1ccc(Oc2nc(NC(C)(C)C)nc(n2)N3CCOCC3)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D15 mock treatment 4206351.0 1130000.0 0.95 3937673.0 762000.0 0.61 1.1044 0.9761 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D16 mock treatment 3990313.0 916000.0 0.77 3624307.0 448000.0 0.36 0.799 0.9387 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D17 compound treatment 3934268.0 860000.0 0.73 3903115.0 727000.0 0.58 0.9227 0.9938 1664661 CBKinase1_019197 O=C(CSc1ncn[nH]1)N(c2ccccc2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D18 compound treatment 4119219.0 1040000.0 0.88 3856831.0 681000.0 0.54 1.0069 0.9729 3629301 CBKinase1_019198 Cc1nnc(SCC(=O)Nc2ccc(F)c(F)c2F)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D19 compound treatment 3869377.0 795000.0 0.67 3536006.0 360000.0 0.29 0.6771 0.9283 3629302 CBKinase1_019199 COc1ccccc1NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccc(Cl)c(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D20 compound treatment 4103288.0 1030000.0 0.87 4074124.0 898000.0 0.72 1.1199 0.9954 3629303 CBKinase1_019200 COc1c(Cl)cc(cc1Cl)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D21 compound treatment 3686901.0 612000.0 0.52 3318008.0 142000.0 0.11 0.4454 0.8421 3629304 CBKinase1_019201 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D22 compound treatment 3642579.0 568000.0 0.48 3148445.0 -27500.0 -0.02 0.3234 0.6741 3629305 CBKinase1_019202 CCn1c2nnc(SCCOc3ccc(C)cc3)n2c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D23 compound treatment 3243113.0 169000.0 0.14 2958373.0 -218000.0 -0.17 -0.022 -0.0982 3629306 CBKinase1_019203 COc1cc(ccc1NC(=S)NCc2cccnc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 D24 compound treatment 2807720.0 -267000.0 -0.23 2568271.0 -608000.0 -0.48 -0.5016 -0.9392 3629307 CBKinase1_019204 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)c(Cl)c1)c2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E01 mock treatment 1270698.0 -1800000.0 -1.52 1070604.0 -2110000.0 -1.68 -2.2624 -0.9988 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E02 mock treatment 1381311.0 -1690000.0 -1.43 1396877.0 -1780000.0 -1.42 -2.0125 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E03 compound treatment 1233020.0 -1840000.0 -1.55 1452399.0 -1720000.0 -1.37 -2.0697 -0.9981 3629308 CBKinase1_019205 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2ccc(Oc3ccccc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E04 compound treatment 1603493.0 -1470000.0 -1.24 1629233.0 -1550000.0 -1.23 -1.7491 -1.0 3629309 CBKinase1_019206 COc1ccc(Cl)cc1NC(=S)NCCn2cc(Br)cn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E05 compound treatment 1474040.0 -1600000.0 -1.35 1564474.0 -1610000.0 -1.28 -1.8628 -0.9997 3629310 CBKinase1_019207 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E06 compound treatment 1804560.0 -1270000.0 -1.07 1988191.0 -1190000.0 -0.95 -1.4268 -0.9981 3629311 CBKinase1_019208 COC(=O)c1ccccc1NC(=O)CSc2nnc([nH]2)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E07 compound treatment 1603899.0 -1470000.0 -1.24 2524850.0 -651000.0 -0.52 -1.244 -0.9252 3629312 CBKinase1_019209 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E08 compound treatment 2244464.0 -830000.0 -0.7 2489266.0 -687000.0 -0.55 -0.882 -0.9926 3629313 CBKinase1_019210 Clc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccc3C(=O)NCc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E09 mock treatment 2405526.0 -669000.0 -0.56 2282482.0 -893000.0 -0.71 -0.9025 -0.9934 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E10 mock treatment 2132170.0 -942000.0 -0.79 2564283.0 -612000.0 -0.49 -0.9067 -0.9725 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E11 compound treatment 2359942.0 -715000.0 -0.6 2288809.0 -887000.0 -0.71 -0.9261 -0.9968 3629314 CBKinase1_019211 COc1ccc(c(C)c1C)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E12 compound treatment 2414368.0 -660000.0 -0.56 2636144.0 -540000.0 -0.43 -0.6979 -0.9919 3629315 CBKinase1_019212 Clc1cc(Cl)cc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E13 compound treatment 2546537.0 -528000.0 -0.45 2843832.0 -332000.0 -0.26 -0.502 -0.9691 3629316 CBKinase1_019213 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E14 compound treatment 2336162.0 -738000.0 -0.62 2282619.0 -893000.0 -0.71 -0.9438 -0.9978 3629317 CBKinase1_019214 COc1cccc(NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E15 compound treatment 2244297.0 -830000.0 -0.7 2465374.0 -711000.0 -0.57 -0.8956 -0.9945 3629318 CBKinase1_019215 COC(=O)c1c(NC(=S)Nc2ccn(C)n2)sc3CCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E16 compound treatment 1776100.0 -1300000.0 -1.1 1863266.0 -1310000.0 -1.05 -1.5142 -0.9997 3629319 CBKinase1_019216 CCOc1ccc2nc(Nc3nc(C)c(CCC(C)C)c(=O)[nH]3)nc(C)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E17 mock treatment 2434189.0 -640000.0 -0.54 2581800.0 -594000.0 -0.47 -0.7167 -0.9979 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E18 mock treatment 2566614.0 -508000.0 -0.43 2635134.0 -541000.0 -0.43 -0.6077 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E19 compound treatment 2629362.0 -445000.0 -0.38 2471667.0 -704000.0 -0.56 -0.6624 -0.9809 3629320 CBKinase1_019217 O=C(CCc1ccccc1)Nc2ccccc2C(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E20 compound treatment 2673419.0 -401000.0 -0.34 1986831.0 -1190000.0 -0.95 -0.9094 -0.9037 3629321 CBKinase1_019218 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(c3)C(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E21 compound treatment 2506533.0 -568000.0 -0.48 2184334.0 -992000.0 -0.79 -0.8976 -0.9712 3629322 CBKinase1_019219 CCc1c(O)nc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E22 compound treatment 2573144.0 -501000.0 -0.42 2363667.0 -812000.0 -0.65 -0.7568 -0.9787 3118574 CBKinase1_019220 Clc1cccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E23 compound treatment 2045985.0 -1030000.0 -0.87 2051730.0 -1120000.0 -0.9 -1.247 -0.9999 3629323 CBKinase1_019221 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3cccc(Cl)c3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 E24 compound treatment 2663721.0 -411000.0 -0.35 1758106.0 -1420000.0 -1.13 -1.0441 -0.8833 3629324 CBKinase1_019222 CCCCc1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F01 mock treatment 1356276.0 -1720000.0 -1.45 938179.0 -2240000.0 -1.78 -2.286 -0.9947 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F02 mock treatment 1798761.0 -1280000.0 -1.08 1530925.0 -1640000.0 -1.31 -1.688 -0.9952 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F03 compound treatment 1444015.0 -1630000.0 -1.38 2341059.0 -835000.0 -0.67 -1.443 -0.9445 3629325 CBKinase1_019223 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccc2c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F04 compound treatment 1569603.0 -1500000.0 -1.27 2431984.0 -744000.0 -0.59 -1.3168 -0.9399 3629326 CBKinase1_019224 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F05 compound treatment 793044.0 -2280000.0 -1.92 752475.0 -2420000.0 -1.93 -2.7266 -1.0 3629327 CBKinase1_019225 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F06 compound treatment 1873771.0 -1200000.0 -1.01 3327364.0 151000.0 0.12 -0.6308 -0.6184 3629328 CBKinase1_019226 COC(=O)c1ccc(C(=O)OC)c(NS(=O)(=O)c2ccc3OCCOc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F07 compound treatment 1735817.0 -1340000.0 -1.13 1825834.0 -1350000.0 -1.08 -1.5593 -0.9997 3629329 CBKinase1_019227 COc1cccc(OCC(=O)Nc2cccc(C(=O)O)c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F08 compound treatment 1937161.0 -1140000.0 -0.96 2122706.0 -1050000.0 -0.84 -1.2719 -0.9978 3629330 CBKinase1_019228 CC(C)(C)C1CCc2c(C#N)c(NC(=O)CSc3nnc([nH]3)c4ccco4)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F09 mock treatment 1852781.0 -1220000.0 -1.03 2505088.0 -671000.0 -0.53 -1.1067 -0.9533 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F10 mock treatment 1942590.0 -1130000.0 -0.95 2157442.0 -1020000.0 -0.81 -1.2491 -0.9967 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F11 compound treatment 2175736.0 -899000.0 -0.76 2319168.0 -857000.0 -0.68 -1.0189 -0.9986 3629331 CBKinase1_019229 O=C1N(CCCc2nc(no2)c3ccncc3)C(=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F12 compound treatment 2245139.0 -829000.0 -0.7 2608459.0 -567000.0 -0.45 -0.8145 -0.9777 3629332 CBKinase1_019230 CCn1ncc(NC(=S)NCc2ccco2)c1C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F13 compound treatment 2053559.0 -1020000.0 -0.86 2127144.0 -1050000.0 -0.84 -1.2 -0.9999 3629333 CBKinase1_019231 COc1cccc(NC(=O)CSc2nnc(c3cccc(C)c3)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F14 compound treatment 2106735.0 -968000.0 -0.82 2275336.0 -901000.0 -0.72 -1.0848 -0.9979 3629334 CBKinase1_019232 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCc5ccco5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F15 compound treatment 2296753.0 -778000.0 -0.66 2664461.0 -511000.0 -0.41 -0.7521 -0.9738 3629335 CBKinase1_019233 COC(=O)c1cc(C)sc1NC(=S)NC(C)c2cn(C)nc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F16 compound treatment 1811333.0 -1260000.0 -1.07 2054797.0 -1120000.0 -0.89 -1.3852 -0.9962 3629336 CBKinase1_019234 COc1ccc(OC)c(NC(=O)Cc2c(OC)ccc3cc(Br)ccc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F17 mock treatment 2121838.0 -953000.0 -0.8 2278359.0 -898000.0 -0.72 -1.074 -0.9983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F18 mock treatment 2345913.0 -729000.0 -0.61 2560051.0 -616000.0 -0.49 -0.7816 -0.9938 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F19 compound treatment 2144656.0 -930000.0 -0.78 1922469.0 -1250000.0 -1.0 -1.261 -0.9928 3629337 CBKinase1_019235 CN(c1ccccc1C(=O)NCC2CCCO2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F20 compound treatment 2108283.0 -966000.0 -0.81 2519127.0 -657000.0 -0.52 -0.9464 -0.9771 3629338 CBKinase1_019236 COC(=O)c1ccccc1NC(=O)Nc2ncn(Cc3cccc(c3)C(F)(F)F)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F21 compound treatment 2441021.0 -633000.0 -0.53 2130742.0 -1050000.0 -0.83 -0.9669 -0.977 3629339 CBKinase1_019237 COC(=O)c1c(NC(=S)NCCn2cc(Br)cn2)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F22 compound treatment 2358623.0 -716000.0 -0.6 2197379.0 -979000.0 -0.78 -0.9785 -0.992 3629340 CBKinase1_019238 CCCC(=O)n1nc(nc1NCc2ccco2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F23 compound treatment 2577452.0 -497000.0 -0.42 1859953.0 -1320000.0 -1.05 -1.0381 -0.919 3629341 CBKinase1_019239 COC(=O)c1c(NC(=S)Nc2cc(OC)c(Cl)cc2OC)sc3CCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 F24 compound treatment 1761010.0 -1310000.0 -1.11 1928560.0 -1250000.0 -0.99 -1.4864 -0.9985 3629342 CBKinase1_019240 CSc1ccccc1NC(=O)Cn2c(nc3ccccc23)c4cscn4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G01 compound treatment 2132469.0 -942000.0 -0.79 2007972.0 -1170000.0 -0.93 -1.2201 -0.9969 3629343 CBKinase1_019241 Cn1c2nnc(SCc3nc4ccc(cc4[nH]3)[N+](=O)[O-])n2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G02 compound treatment 1908962.0 -1170000.0 -0.98 2424481.0 -751000.0 -0.6 -1.1187 -0.9718 3629344 CBKinase1_019242 O=C(CCC(=O)c1ccc(Oc2ccccc2)cc1)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G03 mock treatment 2450948.0 -624000.0 -0.53 2352700.0 -823000.0 -0.66 -0.8359 -0.994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G04 mock treatment 2462267.0 -612000.0 -0.52 2528553.0 -647000.0 -0.52 -0.73 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G05 compound treatment 2745360.0 -329000.0 -0.28 2591047.0 -585000.0 -0.47 -0.5259 -0.9693 1503771 CBKinase1_019243 Fc1cccc(F)c1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G06 compound treatment 2682765.0 -392000.0 -0.33 2749295.0 -427000.0 -0.34 -0.4741 -0.9999 3629345 CBKinase1_019244 COc1c(Cl)cc(cc1Cl)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)nc(C)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G07 compound treatment 2888031.0 -186000.0 -0.16 2935221.0 -241000.0 -0.19 -0.2469 -0.9951 3629346 CBKinase1_019245 COC(=O)c1cccc(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G08 compound treatment 2537034.0 -537000.0 -0.45 2307732.0 -868000.0 -0.69 -0.8098 -0.979 3629347 CBKinase1_019246 CCOc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4ccccc4[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G09 compound treatment 2307954.0 -767000.0 -0.65 2575459.0 -600000.0 -0.48 -0.7956 -0.989 3629348 CBKinase1_019247 Cn1c2nnc(SCC(=O)N3CCN(CC3)c4ccccc4)n2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G10 compound treatment 2662161.0 -412000.0 -0.35 3070559.0 -105000.0 -0.08 -0.3053 -0.8533 3629349 CBKinase1_019248 Cc1nnc(SCC(=O)Nc2cc(C)ccc2F)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G11 compound treatment 2463815.0 -611000.0 -0.52 2604234.0 -572000.0 -0.46 -0.6864 -0.9981 3629350 CBKinase1_019249 Cc1ccccc1NC(=O)CSc2nc(C)c3CCCCc3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G12 compound treatment 2468202.0 -606000.0 -0.51 2856717.0 -319000.0 -0.25 -0.5415 -0.948 3629351 CBKinase1_019250 CN(c1cccc(NC(=O)c2ccccc2N(C)S(=O)(=O)C)c1)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G13 compound treatment 2551179.0 -523000.0 -0.44 2691418.0 -484000.0 -0.39 -0.5852 -0.9978 2068420 CBKinase1_019251 OC(=O)C(CC(=O)Nc1ccc(Cl)cc1Cl)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G14 compound treatment 2566924.0 -508000.0 -0.43 3078944.0 -97000.0 -0.08 -0.3574 -0.8215 3629352 CBKinase1_019252 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3ccc(I)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G15 compound treatment 2541383.0 -533000.0 -0.45 2946832.0 -229000.0 -0.18 -0.4471 -0.9212 3629353 CBKinase1_019253 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(C)o3)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G16 compound treatment 2594502.0 -480000.0 -0.4 2685459.0 -490000.0 -0.39 -0.5627 -0.9998 3629354 CBKinase1_019254 COc1ccc(C)cc1NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G17 compound treatment 2700516.0 -374000.0 -0.32 2910212.0 -266000.0 -0.21 -0.3728 -0.9812 3629355 CBKinase1_019255 Cc1nn(CCCNC(=S)Nc2cccc(c2)[N+](=O)[O-])c(C)c1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G18 compound treatment 2819256.0 -255000.0 -0.22 2923820.0 -252000.0 -0.2 -0.2943 -0.9994 3629356 CBKinase1_019256 Cc1cnn(CCCNC(=O)NC2(CC3CC4CC(C3)C2)C4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G19 mock treatment 3024291.0 -50200.0 -0.04 2790250.0 -386000.0 -0.31 -0.2473 -0.797 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G20 mock treatment 3253563.0 179000.0 0.15 2800157.0 -376000.0 -0.3 -0.105 -0.3129 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G21 compound treatment 3594484.0 520000.0 0.44 2652592.0 -523000.0 -0.42 0.0152 0.0251 3629357 CBKinase1_019257 COC(=O)c1ccc(NC(=O)CSc2nc(C)c(C)c(O)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G22 compound treatment 2617435.0 -457000.0 -0.39 2763519.0 -412000.0 -0.33 -0.505 -0.9969 3629358 CBKinase1_019258 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G23 compound treatment 2741241.0 -333000.0 -0.28 2495146.0 -681000.0 -0.54 -0.5824 -0.9531 3629359 CBKinase1_019259 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 G24 compound treatment 2225032.0 -849000.0 -0.72 2390509.0 -785000.0 -0.63 -0.9493 -0.9977 3629360 CBKinase1_019260 COc1ccc(NC(=S)NCc2cc(C)n(C)n2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H01 compound treatment 1842702.0 -1230000.0 -1.04 2126689.0 -1050000.0 -0.84 -1.326 -0.9942 3629361 CBKinase1_019261 COc1cc2c(cc1NC(=O)COc3ccc(cc3)[N+](=O)[O-])oc4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H02 compound treatment 2844405.0 -230000.0 -0.19 2665930.0 -510000.0 -0.41 -0.4246 -0.9428 1272003 CBKinase1_019262 Nc1cc(N)nc(SCC(=O)N(c2ccccc2)c3ccccc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H03 mock treatment 3200367.0 126000.0 0.11 3126538.0 -49400.0 -0.04 0.0473 0.4174 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H04 mock treatment 2881120.0 -193000.0 -0.16 3223383.0 47500.0 0.04 -0.0886 -0.529 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H05 compound treatment 3136676.0 62200.0 0.05 3021883.0 -154000.0 -0.12 -0.0497 -0.3723 3629362 CBKinase1_019263 OC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(Br)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H06 compound treatment 485465.0 -2590000.0 -2.18 516741.0 -2660000.0 -2.12 -3.0429 -0.9999 3629363 CBKinase1_019264 Clc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=S)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H07 compound treatment 2844314.0 -230000.0 -0.19 2976421.0 -199000.0 -0.16 -0.2497 -0.9951 3629364 CBKinase1_019265 COc1ccc(CC(=O)Nc2cc(C)ccc2O)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H08 compound treatment 3306361.0 232000.0 0.2 3347960.0 172000.0 0.14 0.2353 0.9849 3629365 CBKinase1_019266 CSc1ccccc1NC(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H09 compound treatment 3059102.0 -15400.0 -0.01 3224091.0 48200.0 0.04 0.018 0.4438 3629366 CBKinase1_019267 OC(=O)c1ccccc1NS(=O)(=O)c2cccc(c2)C(=O)N3CCCc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H10 compound treatment 3019054.0 -55400.0 -0.05 3424836.0 249000.0 0.2 0.1072 0.5261 3629367 CBKinase1_019268 COc1cc(ccc1NC(=O)NCc2ccco2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H11 compound treatment 3308955.0 234000.0 0.2 3271206.0 95300.0 0.08 0.1936 0.9136 3629368 CBKinase1_019269 CC(Oc1ccc(Br)cc1)C(=O)Nc2ccccc2[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H12 compound treatment 2953483.0 -121000.0 -0.1 3501659.0 326000.0 0.26 0.1114 0.3994 3629369 CBKinase1_019270 COc1ccc(NC(=S)NCc2cccnc2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H13 compound treatment 3036156.0 -38300.0 -0.03 3359655.0 184000.0 0.15 0.0807 0.5381 3629370 CBKinase1_019271 CCOC(=O)c1c(NC(=O)CC2NCCNC2=O)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H14 compound treatment 2940814.0 -134000.0 -0.11 3231786.0 55900.0 0.04 -0.0482 -0.3978 3629371 CBKinase1_019272 CCc1nnc(SCC(=O)Nc2ccc(cc2)C(=O)OC)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H15 compound treatment 3051303.0 -23200.0 -0.02 3302850.0 127000.0 0.1 0.0577 0.5602 3629372 CBKinase1_019273 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(Cl)s3)c4ccccc24)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H16 compound treatment 3243867.0 169000.0 0.14 3639005.0 463000.0 0.37 0.362 0.9147 3629373 CBKinase1_019274 O=C(CSc1nnc(o1)c2cccnc2)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H17 compound treatment 3242472.0 168000.0 0.14 3394641.0 219000.0 0.17 0.2235 0.9947 3629374 CBKinase1_019275 CN(C)c1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H18 compound treatment 3081780.0 7310.0 0.01 3556422.0 381000.0 0.3 0.2188 0.7213 3629375 CBKinase1_019276 COC(=O)c1cc(sc1NC(=S)NCc2ccccn2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H19 mock treatment 3331403.0 257000.0 0.22 3291382.0 115000.0 0.09 0.2183 0.9273 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H20 mock treatment 3530788.0 456000.0 0.38 3289674.0 114000.0 0.09 0.3363 0.8504 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H21 compound treatment 3138458.0 64000.0 0.05 3168241.0 -7660.0 -0.01 0.0338 0.6231 3629376 CBKinase1_019277 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H22 compound treatment 3118061.0 43600.0 0.04 3161071.0 -14800.0 -0.01 0.0176 0.4567 3629377 CBKinase1_019278 CCOC(=O)c1c(NC(=O)CSc2nc(C)c3CCCCc3n2)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H23 compound treatment 2612026.0 -462000.0 -0.39 2929575.0 -246000.0 -0.2 -0.4147 -0.9495 3629378 CBKinase1_019279 O=C(c1ccco1)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 H24 compound treatment 2500555.0 -574000.0 -0.48 2245577.0 -930000.0 -0.74 -0.8666 -0.9786 3629379 CBKinase1_019280 COC(=O)c1sccc1NC(=S)Nc2sc3CCCc3c2C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I01 compound treatment 2417724.0 -657000.0 -0.55 2571133.0 -605000.0 -0.48 -0.7326 -0.9976 3629380 CBKinase1_019281 Cc1ccc(NS(=O)(=O)c2ccccc2)cc1CN3C(=O)c4ccccc4C3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I02 compound treatment 2471633.0 -603000.0 -0.51 2476314.0 -700000.0 -0.56 -0.7538 -0.9989 3629381 CBKinase1_019282 CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I03 compound treatment 3036499.0 -38000.0 -0.03 3255356.0 79500.0 0.06 0.0221 0.3118 3629382 CBKinase1_019283 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cccc(Cl)c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I04 compound treatment 3066386.0 -8090.0 -0.01 3061091.0 -115000.0 -0.09 -0.0695 -0.7577 3629383 CBKinase1_019284 COc1ccc(OC)c(NC(=O)NCc2cnn(C)c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I05 mock treatment 3321983.0 248000.0 0.21 3370606.0 195000.0 0.16 0.2574 0.9893 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I06 mock treatment 3081954.0 7480.0 0.01 3506950.0 331000.0 0.26 0.191 0.7238 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I07 compound treatment 3250772.0 176000.0 0.15 3188394.0 12500.0 0.01 0.1122 0.7528 3629384 CBKinase1_019285 Cc1ccc(cc1)n2c(SCC(=O)NC3CCCCC3)nnc2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I08 compound treatment 3134909.0 60400.0 0.05 3953949.0 778000.0 0.62 0.4745 0.7627 1658096 CBKinase1_019286 Cc1cc(C)cc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)N)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I09 compound treatment 3109286.0 34800.0 0.03 3560494.0 385000.0 0.31 0.2375 0.7713 3629385 CBKinase1_019287 Cc1cccc(C)c1N(CC(=O)Nc2cc(Cl)ccc2Oc3ccccc3)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I10 compound treatment 3094605.0 20100.0 0.02 3604751.0 429000.0 0.34 0.2537 0.7413 3629386 CBKinase1_019288 COC(=O)c1c(NC(=S)Nc2cnccn2)sc3CC(C)CCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I11 compound treatment 2881010.0 -193000.0 -0.16 3569781.0 394000.0 0.31 0.1066 0.3013 3629387 CBKinase1_019289 COc1cccc(NC(=O)CC2NCCNC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I12 compound treatment 3434046.0 360000.0 0.3 3951704.0 776000.0 0.62 0.6517 0.9462 3629388 CBKinase1_019290 COc1ccc(C)cc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I13 compound treatment 3399173.0 325000.0 0.27 3722850.0 547000.0 0.44 0.5019 0.9749 3629389 CBKinase1_019291 Nc1cc(=O)nc(SCC(=O)N(c2ccccc2)c3ccccc3)n1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I14 compound treatment 3237535.0 163000.0 0.14 3831608.0 656000.0 0.52 0.4668 0.8638 3629390 CBKinase1_019292 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc(Nc4ccccc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I15 compound treatment 3459182.0 385000.0 0.32 3802114.0 626000.0 0.5 0.5824 0.9783 3629391 CBKinase1_019293 COc1ccc(OC)c(c1)C(C)NC(=O)Nc2cccc(c2)C(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I16 compound treatment 3393999.0 320000.0 0.27 3438941.0 263000.0 0.21 0.3388 0.9923 3629392 CBKinase1_019294 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I17 compound treatment 3404128.0 330000.0 0.28 3370462.0 195000.0 0.16 0.3063 0.962 3629393 CBKinase1_019295 COc1ccc(cc1Cl)N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I18 compound treatment 3159705.0 85200.0 0.07 3623834.0 448000.0 0.36 0.3033 0.8328 3629394 CBKinase1_019296 Clc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I19 compound treatment 3704151.0 630000.0 0.53 3298459.0 123000.0 0.1 0.4446 0.8233 3629395 CBKinase1_019297 COc1ccc(NC(=O)NCc2ccco2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I20 compound treatment 3522460.0 448000.0 0.38 3366546.0 191000.0 0.15 0.3746 0.9199 3629396 CBKinase1_019298 COc1ccc(cc1S(=O)(=O)Nc2cccc(c2)C(=O)O)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I21 mock treatment 2883097.0 -191000.0 -0.16 3587808.0 412000.0 0.33 0.118 0.3225 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I22 mock treatment 3457604.0 383000.0 0.32 3711282.0 535000.0 0.43 0.5303 0.9906 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I23 compound treatment 2778329.0 -296000.0 -0.25 3154596.0 -21300.0 -0.02 -0.1886 -0.7534 3629397 CBKinase1_019299 CCNS(=O)(=O)c1ccc(NC(=S)Nc2sc(C)c(C)c2C(=O)OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 I24 compound treatment 2564244.0 -510000.0 -0.43 2724534.0 -451000.0 -0.36 -0.5587 -0.996 3629398 CBKinase1_019300 FC(F)(F)c1cccc(NC(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J01 compound treatment 2988599.0 -85900.0 -0.07 2782703.0 -393000.0 -0.31 -0.2728 -0.8482 3629399 CBKinase1_019301 COC(=O)c1cccc(COC(=O)c2cc(O)nc3ccccc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J02 compound treatment 3184739.0 110000.0 0.09 3233899.0 58000.0 0.05 0.0985 0.9479 3629400 CBKinase1_019302 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J03 compound treatment 3620064.0 546000.0 0.46 3020137.0 -156000.0 -0.12 0.2376 0.4985 3629401 CBKinase1_019303 Cc1cccc(c1)C(=O)Nc2cc(C)ccc2NC(=O)COc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J04 compound treatment 3810485.0 736000.0 0.62 3178394.0 2490.0 0.0 0.4404 0.7094 3629402 CBKinase1_019304 Cc1sc2ncn(CC(=O)Nc3ccc(Cl)cc3C)c(=O)c2c1c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J05 mock treatment 3600240.0 526000.0 0.44 3620836.0 445000.0 0.35 0.5644 0.9939 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J06 mock treatment 3735352.0 661000.0 0.56 3193158.0 17300.0 0.01 0.4039 0.7243 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J07 compound treatment 3827012.0 753000.0 0.63 3999036.0 823000.0 0.66 0.9128 0.9999 3629403 CBKinase1_019305 CC1CCN(CC1)S(=O)(=O)c2cccc(c2)C(=O)NC(C)(C)CO 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J08 compound treatment 3781071.0 707000.0 0.6 3533280.0 357000.0 0.28 0.6229 0.9429 3629404 CBKinase1_019306 COC(=O)c1cc(NC(=O)CN(c2ccccc2F)S(=O)(=O)C)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J09 compound treatment 3476931.0 402000.0 0.34 3363770.0 188000.0 0.15 0.3459 0.9323 3629405 CBKinase1_019307 O=C(Nc1ccccc1)c2ccc(NCC3CCCO3)c(c2)S(=O)(=O)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J10 compound treatment 3314104.0 240000.0 0.2 3330065.0 154000.0 0.12 0.2298 0.9715 3629406 CBKinase1_019308 CSc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J11 compound treatment 3697925.0 623000.0 0.53 3879664.0 704000.0 0.56 0.7685 0.9995 3629407 CBKinase1_019309 CN(CC(=O)Nc1cc(Cl)ccc1O)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J12 compound treatment 3800381.0 726000.0 0.61 3890081.0 714000.0 0.57 0.8355 0.9993 3629408 CBKinase1_019310 [O-][N+](=O)c1cccc(c1)C2N(CCN3CCOCC3)C(=O)c4oc5ccccc5c(=O)c24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J13 compound treatment 3422469.0 348000.0 0.29 3554748.0 379000.0 0.3 0.4211 0.9999 3629409 CBKinase1_019311 Cc1ccc(NC(=O)CC(N)C(=O)O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J14 compound treatment 3730857.0 656000.0 0.55 3876717.0 701000.0 0.56 0.7865 1.0 3629410 CBKinase1_019312 COc1cccc(CN2CCN(CC2)C(=S)NCc3ccco3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J15 compound treatment 3922106.0 848000.0 0.71 4343980.0 1170000.0 0.93 1.1639 0.9915 3629411 CBKinase1_019313 CCOC(=O)c1c(NC(=S)Nc2cc(OC)c(Cl)cc2OC)sc(C)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J16 compound treatment 3819540.0 745000.0 0.63 3578089.0 402000.0 0.32 0.6711 0.9512 3629412 CBKinase1_019314 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(CC(O)COc3ccc4ccccc4c3)CC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J17 compound treatment 3749329.0 675000.0 0.57 4227506.0 1050000.0 0.84 0.9952 0.9822 3629413 CBKinase1_019315 COc1ccc2cc(Br)ccc2c1CC(=O)Nc3ccccc3OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J18 compound treatment 3991583.0 917000.0 0.77 4336631.0 1160000.0 0.93 1.2012 0.996 3629414 CBKinase1_019316 Cc1cccnc1NC(=S)Nc2ccc(cc2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J19 compound treatment 3835351.0 761000.0 0.64 3512368.0 336000.0 0.27 0.6434 0.9251 3629415 CBKinase1_019317 CCOC(=O)c1c(NC(=S)NC(C)C2CCCO2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J20 compound treatment 3919207.0 845000.0 0.71 3856741.0 681000.0 0.54 0.8876 0.991 3629416 CBKinase1_019318 COc1ccc(C)c(Cn2c(nc3ccccc23)c4nonc4N)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J21 mock treatment 4012501.0 938000.0 0.79 3811199.0 635000.0 0.51 0.9175 0.9767 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J22 mock treatment 3731132.0 657000.0 0.55 3813819.0 638000.0 0.51 0.7512 0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J23 compound treatment 3334483.0 260000.0 0.22 2894329.0 -282000.0 -0.22 -0.0036 -0.0115 1985090 CBKinase1_019319 Fc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 J24 compound treatment 3046707.0 -27800.0 -0.02 2741845.0 -434000.0 -0.35 -0.2612 -0.7533 3629417 CBKinase1_019320 O=C(CSc1nnc([nH]1)c2ccco2)N3c4ccccc4Sc5ccccc35 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K01 compound treatment 1658449.0 -1420000.0 -1.19 1570082.0 -1610000.0 -1.28 -1.7496 -0.9994 3629418 CBKinase1_019321 COC(=O)c1c(NC(=S)Nc2ccn(n2)C3(CC4CC5CC(C4)C3)C5)sc6CCCc16 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K02 compound treatment 2528504.0 -546000.0 -0.46 3288397.0 112000.0 0.09 -0.2622 -0.5589 1209698 CBKinase1_019322 CSc1ccccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K03 compound treatment 2765821.0 -309000.0 -0.26 2878691.0 -297000.0 -0.24 -0.3516 -0.9989 3629419 CBKinase1_019323 COC(=O)c1ccccc1NC(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K04 compound treatment 2863212.0 -211000.0 -0.18 3171864.0 -4040.0 0.0 -0.1283 -0.7198 3629420 CBKinase1_019324 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K05 compound treatment 2922133.0 -152000.0 -0.13 2916181.0 -260000.0 -0.21 -0.2372 -0.9737 3629421 CBKinase1_019325 CCN1CCN(CC1)C(=O)C(C)N(c2ccc(OC)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K06 compound treatment 3059517.0 -15000.0 -0.01 2922107.0 -254000.0 -0.2 -0.152 -0.7497 3629422 CBKinase1_019326 COc1ccc(OCC(=O)Nc2c(oc3ccccc23)C(=O)c4ccc(C)c(F)c4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K07 mock treatment 2858502.0 -216000.0 -0.18 2751551.0 -424000.0 -0.34 -0.368 -0.9579 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K08 mock treatment 2473690.0 -601000.0 -0.51 2668974.0 -507000.0 -0.4 -0.644 -0.9937 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K09 compound treatment 2376717.0 -698000.0 -0.59 2427794.0 -748000.0 -0.6 -0.8378 -1.0 3629423 CBKinase1_019327 COc1ccccc1N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K10 compound treatment 2478453.0 -596000.0 -0.5 2723540.0 -452000.0 -0.36 -0.6104 -0.9867 3629424 CBKinase1_019328 COc1ccccc1NC(=O)Cn2nnc(n2)c3cc(OC)c(OC)c(OC)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K11 compound treatment 2951396.0 -123000.0 -0.1 2671005.0 -505000.0 -0.4 -0.358 -0.8613 3629425 CBKinase1_019329 Cc1cc(C)cc(c1)N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K12 compound treatment 2552936.0 -522000.0 -0.44 2926678.0 -249000.0 -0.2 -0.4515 -0.9355 3629426 CBKinase1_019330 COc1ccc(cc1OC)C(=O)NC(CC(C)C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K13 compound treatment 2535967.0 -539000.0 -0.45 2994611.0 -181000.0 -0.14 -0.4234 -0.8882 3629427 CBKinase1_019331 COc1cc(ccc1NC(=O)Nc2ncccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K14 compound treatment 2539044.0 -535000.0 -0.45 2617067.0 -559000.0 -0.45 -0.6343 -1.0 3629428 CBKinase1_019332 COc1ccc(Cl)cc1NC(=S)Nc2cccc(c2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K15 mock treatment 2629182.0 -445000.0 -0.38 2858021.0 -318000.0 -0.25 -0.4447 -0.9816 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K16 mock treatment 2456770.0 -618000.0 -0.52 3048749.0 -127000.0 -0.1 -0.4401 -0.8291 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K17 compound treatment 3020651.0 -53800.0 -0.05 2965473.0 -210000.0 -0.17 -0.1507 -0.8673 2068184 CBKinase1_019333 Cc1ccc(C)c(NC(=O)CC(NC2CCCCC2)C(=O)O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K18 compound treatment 2931275.0 -143000.0 -0.12 2691276.0 -485000.0 -0.39 -0.3585 -0.8859 3629429 CBKinase1_019334 COc1ccc(CCNC(=O)c2ccnc(c2)C(C)(C)C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K19 compound treatment 2887100.0 -187000.0 -0.16 3180196.0 4290.0 0.0 -0.1093 -0.6916 3629430 CBKinase1_019335 COC(=O)c1cc(Cc2ccccc2)sc1NC(=S)Nc3ccn(C)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K20 compound treatment 3349070.0 275000.0 0.23 2444051.0 -732000.0 -0.58 -0.2487 -0.3962 3629431 CBKinase1_019336 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)N5CCN(CCO)CC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K21 compound treatment 3585269.0 511000.0 0.43 3363749.0 188000.0 0.15 0.4105 0.9 3629432 CBKinase1_019337 CCN1CCN(CC1)C(=O)CN(c2ccc(OC)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K22 compound treatment 2981024.0 -93400.0 -0.08 2481582.0 -694000.0 -0.55 -0.4471 -0.7998 3629433 CBKinase1_019338 COc1ccccc1N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K23 mock treatment 2688271.0 -386000.0 -0.33 2574246.0 -602000.0 -0.48 -0.5694 -0.9822 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 K24 mock treatment 2289561.0 -785000.0 -0.66 2606469.0 -569000.0 -0.45 -0.7891 -0.983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L01 compound treatment 2374673.0 -700000.0 -0.59 2591759.0 -584000.0 -0.47 -0.7466 -0.9931 3629434 CBKinase1_019339 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L02 compound treatment 3379755.0 305000.0 0.26 3192385.0 16500.0 0.01 0.1914 0.7422 3629435 CBKinase1_019340 COC(=O)c1ccc(Cl)c(NC(=O)COc2ccc(OC)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L03 compound treatment 2989460.0 -85000.0 -0.07 2931743.0 -244000.0 -0.19 -0.1883 -0.908 3629436 CBKinase1_019341 CC(Oc1ccc(Br)cc1)C(=O)Nc2nnc[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L04 compound treatment 3645598.0 571000.0 0.48 3070083.0 -106000.0 -0.08 0.281 0.5746 3629437 CBKinase1_019342 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccc(C)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L05 compound treatment 3428553.0 354000.0 0.3 2968158.0 -208000.0 -0.17 0.0941 0.2756 3629438 CBKinase1_019343 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3ccccc3I)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L06 compound treatment 3152522.0 78000.0 0.07 2778380.0 -398000.0 -0.32 -0.1775 -0.5485 3629439 CBKinase1_019344 COc1ccc(NC(=O)Cn2c(nc3sc4CCCCc4c3c2=O)c5ccccc5)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L07 mock treatment 3129935.0 55500.0 0.05 3526765.0 351000.0 0.28 0.2308 0.8141 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L08 mock treatment 3128944.0 54500.0 0.05 3520662.0 345000.0 0.27 0.2268 0.814 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L09 compound treatment 3089689.0 15200.0 0.01 3626265.0 450000.0 0.36 0.2629 0.7319 1365377 CBKinase1_019345 COC(=O)c1cccc(NC(=O)COc2cc(C)ccc2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L10 compound treatment 3181700.0 107000.0 0.09 3907058.0 731000.0 0.58 0.476 0.8072 3629440 CBKinase1_019346 CS(=O)(=O)N(CC(=O)Nc1ccccc1Sc2ccccc2)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L11 compound treatment 3247746.0 173000.0 0.15 3528843.0 353000.0 0.28 0.3023 0.9535 3629441 CBKinase1_019347 Cc1cccc(OCC(=O)Nc2cccc(C(=O)O)c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L12 compound treatment 3219713.0 145000.0 0.12 3796166.0 620000.0 0.49 0.4362 0.8564 3629442 CBKinase1_019348 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L13 compound treatment 2905863.0 -169000.0 -0.14 3668524.0 493000.0 0.39 0.1771 0.424 1986239 CBKinase1_019349 CCn1c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L14 compound treatment 3311298.0 237000.0 0.2 3928894.0 753000.0 0.6 0.5656 0.8942 3629443 CBKinase1_019350 CC(C)N(Cc1nc(no1)c2ccc(Cl)cc2)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L15 mock treatment 3543645.0 469000.0 0.4 3695646.0 520000.0 0.41 0.5728 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L16 mock treatment 3732279.0 658000.0 0.55 3115150.0 -60800.0 -0.05 0.3581 0.643 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L17 compound treatment 3663428.0 589000.0 0.5 3907419.0 732000.0 0.58 0.7636 0.9968 3629444 CBKinase1_019351 CC(=O)c1cccc(NC(=S)NCc2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L18 compound treatment 3845663.0 771000.0 0.65 3871005.0 695000.0 0.55 0.8517 0.9968 3629445 CBKinase1_019352 CCN1CCN(CC1)C(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L19 compound treatment 3697033.0 623000.0 0.53 3954860.0 779000.0 0.62 0.8103 0.9965 3629446 CBKinase1_019353 Cc1ccccc1c2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L20 compound treatment 2715820.0 -359000.0 -0.3 4079549.0 904000.0 0.72 0.2954 0.3781 3629447 CBKinase1_019354 COC(=O)c1sc(NC(=S)Nc2cc(OC)c(Cl)cc2OC)c(C(=O)OC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L21 compound treatment 3223773.0 149000.0 0.13 2826924.0 -349000.0 -0.28 -0.1076 -0.3525 3629448 CBKinase1_019355 Oc1c(Sc2nc[nH]n2)cc(NS(=O)(=O)c3cccs3)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L22 compound treatment 4161910.0 1090000.0 0.92 3626356.0 450000.0 0.36 0.9025 0.9162 3629449 CBKinase1_019356 FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L23 mock treatment 3781676.0 707000.0 0.6 3472710.0 297000.0 0.24 0.5891 0.918 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 L24 mock treatment 3014057.0 -60400.0 -0.05 3034805.0 -141000.0 -0.11 -0.1156 -0.9359 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M01 compound treatment 2251897.0 -823000.0 -0.69 1726829.0 -1450000.0 -1.15 -1.3073 -0.9703 3629450 CBKinase1_019357 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M02 compound treatment 2601911.0 -473000.0 -0.4 2427838.0 -748000.0 -0.6 -0.7035 -0.9808 3629451 CBKinase1_019358 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3cccc4cccnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M03 compound treatment 2735779.0 -339000.0 -0.29 2406343.0 -770000.0 -0.61 -0.6357 -0.9395 3629452 CBKinase1_019359 COc1ccc(cc1NC(=S)NCc2ccco2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M04 compound treatment 2579951.0 -495000.0 -0.42 2845131.0 -331000.0 -0.26 -0.4814 -0.9755 3629453 CBKinase1_019360 COc1ccc(Cl)cc1NC(=O)CC2N(CCNC2=O)C(=S)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M05 compound treatment 3223667.0 149000.0 0.13 2957353.0 -219000.0 -0.17 -0.0342 -0.1591 3629454 CBKinase1_019361 OC1(CC(=O)c2cccc(c2)n3cccc3)C(=O)Nc4ccc(Br)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M06 compound treatment 2403548.0 -671000.0 -0.57 1938350.0 -1240000.0 -0.99 -1.0976 -0.9652 3629455 CBKinase1_019362 CCOC(=O)c1c(NC(=S)NC(C)c2ccncc2)sc3CCCCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M07 compound treatment 3354218.0 280000.0 0.24 3454008.0 278000.0 0.22 0.3236 0.9995 3629456 CBKinase1_019363 Cc1ccccc1NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M08 compound treatment 3211987.0 138000.0 0.12 3285591.0 110000.0 0.09 0.1438 0.9903 3629457 CBKinase1_019364 Cc1cc(C)c(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Br)cc3)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M09 mock treatment 3363470.0 289000.0 0.24 3529533.0 354000.0 0.28 0.3717 0.9974 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M10 mock treatment 3260731.0 186000.0 0.16 3238316.0 62400.0 0.05 0.1463 0.8876 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M11 compound treatment 3449035.0 375000.0 0.32 3135489.0 -40400.0 -0.03 0.2006 0.6317 3629458 CBKinase1_019365 Cc1ccc(s1)C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M12 compound treatment 2996095.0 -78400.0 -0.07 2956278.0 -220000.0 -0.18 -0.1705 -0.9113 3629459 CBKinase1_019366 CCN1CCN(CC1)C(=O)C(C)N(c2ccccc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M13 mock treatment 3078570.0 4100.0 0.0 3415559.0 240000.0 0.19 0.1375 0.7198 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M14 mock treatment 3459687.0 385000.0 0.32 3200330.0 24400.0 0.02 0.2435 0.7481 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M15 compound treatment 3440778.0 366000.0 0.31 3319692.0 144000.0 0.11 0.2995 0.9089 3629460 CBKinase1_019367 COc1ccc(cc1Cl)C(=O)c2oc3ccccc3c2NC(=O)COc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M16 compound treatment 3522316.0 448000.0 0.38 3493387.0 317000.0 0.25 0.446 0.981 3629461 CBKinase1_019368 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M17 compound treatment 3293522.0 219000.0 0.18 3753643.0 578000.0 0.46 0.4563 0.9196 3629462 CBKinase1_019369 CCN1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M18 compound treatment 3211702.0 137000.0 0.12 3516144.0 340000.0 0.27 0.2736 0.9279 3629463 CBKinase1_019370 Cc1ccc(cc1NC(=O)CN2C(=O)c3cccc4cccc2c34)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M19 compound treatment 3638903.0 564000.0 0.48 3337460.0 162000.0 0.13 0.4277 0.8672 3629464 CBKinase1_019371 Cc1c(CCC(=O)O)c(=O)oc2c(C)c(OCc3ccc(Br)cc3F)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M20 compound treatment 3700752.0 626000.0 0.53 3347226.0 171000.0 0.14 0.4701 0.8616 3629465 CBKinase1_019372 COC(=O)c1c(NC(=S)N(C)Cc2c(C)nn(C)c2C)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M21 compound treatment 3982115.0 908000.0 0.77 3074219.0 -102000.0 -0.08 0.484 0.6287 3629466 CBKinase1_019373 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2cccc(Cl)c2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M22 compound treatment 3245101.0 171000.0 0.14 3107567.0 -68300.0 -0.05 0.0633 0.4111 3629467 CBKinase1_019374 COc1cc(C)c(Cl)cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M23 compound treatment 3852395.0 778000.0 0.66 3185525.0 9620.0 0.01 0.4694 0.7153 3629468 CBKinase1_019375 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 M24 compound treatment 2720504.0 -354000.0 -0.3 2574839.0 -601000.0 -0.48 -0.5499 -0.9741 3629469 CBKinase1_019376 CSc1ccccc1NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N01 compound treatment 3055093.0 -19400.0 -0.02 2321702.0 -854000.0 -0.68 -0.493 -0.7239 3629470 CBKinase1_019377 Cc1cccc(C)c1OCC(=O)Nc2cccc(c2)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N02 compound treatment 2675674.0 -399000.0 -0.34 2381796.0 -794000.0 -0.63 -0.6854 -0.9562 3629471 CBKinase1_019378 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccccc4C(=O)N5CCOCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N03 compound treatment 3081064.0 6590.0 0.01 3657084.0 481000.0 0.38 0.2751 0.7173 3629472 CBKinase1_019379 COC(=O)c1cn(C(=O)CCCN2C(=O)c3ccccc3C2=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N04 compound treatment 2893417.0 -181000.0 -0.15 2964510.0 -211000.0 -0.17 -0.2271 -0.9988 3629473 CBKinase1_019380 Fc1cc(F)c(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N05 compound treatment 3559298.0 485000.0 0.41 2514091.0 -662000.0 -0.53 -0.0838 -0.1256 3629474 CBKinase1_019381 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccc2N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N06 compound treatment 3540829.0 466000.0 0.39 3136169.0 -39700.0 -0.03 0.2558 0.6481 3629475 CBKinase1_019382 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N07 compound treatment 3299362.0 225000.0 0.19 3564168.0 388000.0 0.31 0.353 0.9724 3629476 CBKinase1_019383 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccccc3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N08 compound treatment 3608089.0 534000.0 0.45 3135986.0 -39900.0 -0.03 0.2958 0.6555 3629477 CBKinase1_019384 Fc1ccc(cc1)C(CCNC(=O)c2cccs2)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N09 mock treatment 3612985.0 539000.0 0.45 3561659.0 386000.0 0.31 0.5386 0.9819 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N10 mock treatment 3600135.0 526000.0 0.44 3924352.0 748000.0 0.6 0.7353 0.9893 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N11 compound treatment 3564293.0 490000.0 0.41 3498789.0 323000.0 0.26 0.4741 0.974 3629478 CBKinase1_019385 Fc1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c(F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N12 compound treatment 3781557.0 707000.0 0.6 3945678.0 770000.0 0.61 0.8556 0.9999 3629479 CBKinase1_019386 COC(=O)c1cc(NC(=O)CN2C(=O)c3cccc4cccc2c34)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N13 mock treatment 3483525.0 409000.0 0.35 3186657.0 10800.0 0.01 0.25 0.7244 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N14 mock treatment 3271251.0 197000.0 0.17 3463612.0 288000.0 0.23 0.2795 0.9874 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N15 compound treatment 3363712.0 289000.0 0.24 3766793.0 591000.0 0.47 0.5055 0.9531 3629480 CBKinase1_019387 Cc1cc(F)ccc1S(=O)(=O)N(C(=O)c2ccncc2)c3ccc(OC(=O)c4ccncc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N16 compound treatment 4051544.0 977000.0 0.82 3978607.0 803000.0 0.64 1.0352 0.9922 3629481 CBKinase1_019388 COc1cccc(c1)N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N17 compound treatment 3533342.0 459000.0 0.39 4132889.0 957000.0 0.76 0.813 0.9505 3629482 CBKinase1_019389 CCc1c(C)sc(NC(=S)NCc2ccco2)c1C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N18 compound treatment 3270051.0 196000.0 0.16 4129222.0 953000.0 0.76 0.6539 0.841 3629483 CBKinase1_019390 CCn1ccc(CNC(=O)Nc2ccc(Cl)cc2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N19 compound treatment 3068635.0 -5840.0 0.0 3782953.0 607000.0 0.48 0.3386 0.6999 3629484 CBKinase1_019391 Cc1ccc(C)c(c1)C(=O)CCC(=O)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N20 compound treatment 3357872.0 283000.0 0.24 4289895.0 1110000.0 0.89 0.7969 0.8666 3629485 CBKinase1_019392 CCn1cc(CN(C)C(=S)Nc2cccc(c2)C(=O)C)c(C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N21 compound treatment 3695508.0 621000.0 0.52 3682681.0 507000.0 0.4 0.656 0.9917 3629486 CBKinase1_019393 CCOC(=O)c1sc(NC(=S)N2CCN(CC2)c3ncccn3)c(C(=O)OCC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N22 compound treatment 3307910.0 233000.0 0.2 3326391.0 150000.0 0.12 0.224 0.9717 3629487 CBKinase1_019394 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N23 compound treatment 3300777.0 226000.0 0.19 3277740.0 102000.0 0.08 0.1924 0.9274 3629488 CBKinase1_019395 CCc1ccccc1NC(=O)CC2NCCNC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 N24 compound treatment 3036463.0 -38000.0 -0.03 3168986.0 -6920.0 -0.01 -0.0266 -0.8167 3629489 CBKinase1_019396 Cc1cc(=O)oc2cc(NC(=S)NCc3cccnc3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O01 compound treatment 2928456.0 -146000.0 -0.12 2175535.0 -1000000.0 -0.8 -0.6509 -0.8068 3629490 CBKinase1_019397 Cc1ccc(c(C)c1)S(=O)(=O)Nc2cc(Sc3nc[nH]n3)c(O)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O02 compound treatment 3382270.0 308000.0 0.26 3151598.0 -24300.0 -0.02 0.1699 0.6525 3629491 CBKinase1_019398 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O03 compound treatment 2641013.0 -433000.0 -0.37 3218926.0 43000.0 0.03 -0.2343 -0.638 3629492 CBKinase1_019399 CCOC(=O)c1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O04 compound treatment 2680590.0 -394000.0 -0.33 3588853.0 413000.0 0.33 -0.0022 -0.0047 3629493 CBKinase1_019400 Cc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O05 compound treatment 2701637.0 -373000.0 -0.31 4127691.0 952000.0 0.76 0.314 0.3824 3629494 CBKinase1_019401 COc1ccc(Cl)cc1NC(=O)CN2C(=O)COc3ccc(Cl)cc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O06 compound treatment 3403417.0 329000.0 0.28 3000073.0 -176000.0 -0.14 0.0971 0.3124 3629495 CBKinase1_019402 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O07 compound treatment 3108719.0 34200.0 0.03 3141221.0 -34700.0 -0.03 9.0E-4 0.022 3629496 CBKinase1_019403 CCCOc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O08 compound treatment 3028203.0 -46300.0 -0.04 3104220.0 -71700.0 -0.06 -0.068 -0.9827 3629497 CBKinase1_019404 Cc1c(Cl)cccc1NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O09 compound treatment 3433721.0 359000.0 0.3 3399247.0 223000.0 0.18 0.3401 0.9679 3629498 CBKinase1_019405 CC(Sc1nc(C)cc(C)n1)C(=O)Nc2cccc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O10 compound treatment 2712700.0 -362000.0 -0.31 2937058.0 -239000.0 -0.19 -0.3504 -0.9742 3629499 CBKinase1_019406 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O11 mock treatment 3171164.0 96700.0 0.08 3655260.0 479000.0 0.38 0.3278 0.8391 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O12 mock treatment 3427145.0 353000.0 0.3 4089341.0 913000.0 0.73 0.7252 0.922 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O13 compound treatment 3451158.0 377000.0 0.32 3989100.0 813000.0 0.65 0.683 0.9462 3629500 CBKinase1_019407 COc1ccccc1NC(=O)CSc2nnnn2c3c(C)cccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O14 compound treatment 3756830.0 682000.0 0.58 3750036.0 574000.0 0.46 0.7306 0.9935 3629501 CBKinase1_019408 Clc1ccc(NC(=O)CSc2nnc(o2)c3ccncc3)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O15 compound treatment 3898121.0 824000.0 0.69 4209191.0 1030000.0 0.82 1.0736 0.9964 3629502 CBKinase1_019409 CN(c1ccccc1C(=O)NCc2ccccn2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O16 compound treatment 3512908.0 438000.0 0.37 4025555.0 850000.0 0.68 0.7404 0.9595 3629503 CBKinase1_019410 Cc1c(NC(=O)CSc2nc(C)c(C)c(O)n2)c(=O)n(c3ccccc3)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O17 compound treatment 3948322.0 874000.0 0.74 4476621.0 1300000.0 1.04 1.2543 0.986 3629504 CBKinase1_019411 CC1CCCCC1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O18 compound treatment 3380365.0 306000.0 0.26 4109899.0 934000.0 0.74 0.7088 0.8997 3629505 CBKinase1_019412 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O19 compound treatment 4286685.0 1210000.0 1.02 4116852.0 941000.0 0.75 1.2533 0.9884 3629506 CBKinase1_019413 CC(NC(=S)NCc1ccco1)C2CCCO2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O20 compound treatment 4137377.0 1060000.0 0.9 4128643.0 953000.0 0.76 1.1709 0.9966 3629507 CBKinase1_019414 COC(=O)c1sc2cc(NC(=S)NCCn3cc(Br)cn3)ccc2c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O21 compound treatment 3915985.0 842000.0 0.71 4188096.0 1010000.0 0.81 1.0724 0.998 3629508 CBKinase1_019415 O=C(CCC(=O)c1ccc(cc1)c2ccccc2)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O22 compound treatment 3578424.0 504000.0 0.43 3602279.0 426000.0 0.34 0.5409 0.9938 3629509 CBKinase1_019416 CCc1nnc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O23 compound treatment 3373588.0 299000.0 0.25 3320115.0 144000.0 0.11 0.2597 0.9366 3629510 CBKinase1_019417 O=C(CN1C(=O)COc2ccccc12)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 O24 compound treatment 2098266.0 -976000.0 -0.82 2967405.0 -208000.0 -0.17 -0.6998 -0.833 3629511 CBKinase1_019418 [O-][N+](=O)c1ncn(CC(=O)Nc2ccc(Cl)cc2C(F)(F)F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P01 compound treatment 2075701.0 -999000.0 -0.84 2365433.0 -810000.0 -0.65 -1.0525 -0.9914 3629512 CBKinase1_019419 NC(=O)c1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P02 compound treatment 3480991.0 407000.0 0.34 2585776.0 -590000.0 -0.47 -0.0901 -0.1548 3629513 CBKinase1_019420 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cccc(Br)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P03 compound treatment 2868812.0 -206000.0 -0.17 3194196.0 18300.0 0.01 -0.1124 -0.6454 3629514 CBKinase1_019421 COC(=O)c1cccc(COC(=O)c2ccc(NC(=O)c3ccco3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P04 compound treatment 3058788.0 -15700.0 -0.01 2926603.0 -249000.0 -0.2 -0.1499 -0.7525 3629515 CBKinase1_019422 COc1ccc(CC(=O)NCc2nnc(S)n2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P05 compound treatment 2331748.0 -743000.0 -0.63 2505279.0 -671000.0 -0.53 -0.821 -0.9969 3629516 CBKinase1_019423 CC(=O)Nc1ccccc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P06 compound treatment 2767460.0 -307000.0 -0.26 3079589.0 -96300.0 -0.08 -0.2374 -0.8789 3629517 CBKinase1_019424 COc1ccc(Cl)cc1NC(=S)NCCCn2nc(C)c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P07 compound treatment 2739561.0 -335000.0 -0.28 3175701.0 -203.0 0.0 -0.1999 -0.7075 1565142 CBKinase1_019425 CN(C)S(=O)(=O)c1cc(C(=O)NCC2CCCO2)c(Cl)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P08 compound treatment 3135296.0 60800.0 0.05 3224369.0 48500.0 0.04 0.0636 0.9902 3629518 CBKinase1_019426 CN(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P09 compound treatment 2720235.0 -354000.0 -0.3 3023084.0 -153000.0 -0.12 -0.2974 -0.9217 3629519 CBKinase1_019427 COc1ccc(cc1NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c3nc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P10 compound treatment 2470934.0 -604000.0 -0.51 2985028.0 -191000.0 -0.15 -0.4676 -0.88 3629520 CBKinase1_019428 COC(=O)CCSc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P11 mock treatment 2837055.0 -237000.0 -0.2 3104145.0 -71800.0 -0.06 -0.182 -0.8741 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P12 mock treatment 2806022.0 -268000.0 -0.23 5217351.0 2040000.0 1.63 0.9904 0.6029 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P13 compound treatment 2852713.0 -222000.0 -0.19 2974935.0 -201000.0 -0.16 -0.2455 -0.997 3629521 CBKinase1_019429 COC(=O)c1c(NC(=S)Nc2cc(OC)c(OC)cc2C(=O)OC)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P14 compound treatment 3408326.0 334000.0 0.28 3623156.0 447000.0 0.36 0.4512 0.9932 3629522 CBKinase1_019430 COc1cc(cc(OC)c1OC)c2nnn(CC(=O)O)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P15 compound treatment 3355243.0 281000.0 0.24 3919690.0 744000.0 0.59 0.5867 0.919 3629523 CBKinase1_019431 Cn1c(=O)n(C)c2ncn(CC(=O)NCc3ccccc3Cl)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P16 compound treatment 3375078.0 301000.0 0.25 4066893.0 891000.0 0.71 0.6815 0.9037 1986351 CBKinase1_019432 Cc1ccc2nsnc2c1S(=O)(=O)N3CCN=C3Cc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P17 compound treatment 3194522.0 120000.0 0.1 3676211.0 500000.0 0.4 0.3536 0.8594 3629524 CBKinase1_019433 FC(F)(F)c1cccc(NC(=O)CC2NC3CCCCC3NC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P18 compound treatment 3110287.0 35800.0 0.03 3743442.0 568000.0 0.45 0.3412 0.7527 3629525 CBKinase1_019434 O=C(C1CCCO1)N2CCN(CC2)C(=S)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P19 compound treatment 3456777.0 382000.0 0.32 3452098.0 276000.0 0.22 0.3837 0.9827 3629526 CBKinase1_019435 CCOc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4cc5ccccc5oc4=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P20 compound treatment 3445122.0 371000.0 0.31 3596206.0 420000.0 0.33 0.458 0.9994 2068347 CBKinase1_019436 Cc1ccc(Cl)cc1NC(=O)CC(N2CCNCC2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P21 compound treatment 3546532.0 472000.0 0.4 3511956.0 336000.0 0.27 0.471 0.9814 3629527 CBKinase1_019437 Cc1ccc2oc(nc2c1)c3cc(NC(=O)c4nc[nH]n4)ccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P22 compound treatment 4079628.0 1010000.0 0.85 3358658.0 183000.0 0.15 0.7025 0.8166 1515306 CBKinase1_019438 COC(=O)c1ccccc1NC(=O)NCc2ccc(OC)c(OC)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P23 compound treatment 3204970.0 130000.0 0.11 3213622.0 37700.0 0.03 0.0991 0.8684 3629528 CBKinase1_019439 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2384 P24 compound treatment 2798523.0 -276000.0 -0.23 2738843.0 -437000.0 -0.35 -0.4109 -0.9808 3629529 CBKinase1_019440 O=C(Nc1ccccc1C(=O)N2CCOCC2)c3ccc(CN4CCOCC4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A01 compound treatment 2716133.0 -488000.0 -0.41 3012111.0 -117000.0 -0.09 -0.3575 -0.8461 3632544 CBKinase1_022641 CC(C)CNc1nc(SCC(=O)N)nc(n1)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A02 compound treatment 2873794.0 -331000.0 -0.28 2753781.0 -376000.0 -0.3 -0.409 -0.9994 3632545 CBKinase1_022642 Nc1nonc1C(=O)NCCNCc2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A03 compound treatment 4392943.0 1190000.0 1.0 3478591.0 349000.0 0.28 0.9056 0.8705 3632546 CBKinase1_022643 COC(=O)c1ccccc1NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A04 compound treatment 2770812.0 -434000.0 -0.37 3587135.0 458000.0 0.36 -8.0E-4 -0.0015 3632547 CBKinase1_022644 CN1CCN(CC1)c2ccccc2NC(=O)COc3cc(C)cc(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A05 compound treatment 2817732.0 -387000.0 -0.33 2699383.0 -430000.0 -0.34 -0.4731 -0.9997 3632548 CBKinase1_022645 C(Sc1nnc2n(Cc3ccccc3)c4ccccc4n12)c5nc6ccccc6[nH]5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A06 compound treatment 4282024.0 1080000.0 0.91 2416777.0 -713000.0 -0.57 0.241 0.2248 3632549 CBKinase1_022646 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3cc(ccc3C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A07 compound treatment 3417353.0 213000.0 0.18 3490469.0 361000.0 0.29 0.3304 0.9742 3632550 CBKinase1_022647 O=C(CSc1nc(nc(n1)N2CCCCC2)N3CCCCC3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A08 compound treatment 2270129.0 -934000.0 -0.79 2035306.0 -1090000.0 -0.87 -1.174 -0.9987 3632551 CBKinase1_022648 COc1ccc(NC(=O)C(C)Sc2nnc3c4COC(C)(C)Cc4nc(c5ccc(OC)cc5)n23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A09 compound treatment 3664378.0 460000.0 0.39 4243326.0 1110000.0 0.89 0.902 0.931 3632552 CBKinase1_022649 [O-][N+](=O)c1cccc(c1)c2ccc(o2)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A10 compound treatment 3670150.0 466000.0 0.39 3293320.0 164000.0 0.13 0.37 0.8941 3632553 CBKinase1_022650 Oc1cc(NC(=O)c2cc(ccc2Cl)n3cnnc3)ccc1c4nc5ccccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A11 compound treatment 3408165.0 204000.0 0.17 3099854.0 -29600.0 -0.02 0.1047 0.6043 3632554 CBKinase1_022651 O=C(OCc1cccc(c1)C(=O)c2ccccc2)c3ccc(cc3)c4nnc(o4)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A12 compound treatment 3627736.0 423000.0 0.36 3340281.0 211000.0 0.17 0.3712 0.9409 3632555 CBKinase1_022652 COc1ccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A13 mock treatment 3721481.0 517000.0 0.44 3509692.0 380000.0 0.3 0.5226 0.9842 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A14 mock treatment 3458977.0 254000.0 0.21 3209429.0 80000.0 0.06 0.1968 0.8792 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A15 compound treatment 3546253.0 342000.0 0.29 3640487.0 511000.0 0.41 0.4918 0.9856 3632556 CBKinase1_022653 COc1cc(CO)cc(Cl)c1OCC(=O)Nc2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A16 compound treatment 4003635.0 799000.0 0.67 3392895.0 263000.0 0.21 0.6251 0.8854 3632557 CBKinase1_022654 COc1ccc(cc1NC(=O)CCC2COc3ccccc3O2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A17 compound treatment 3935171.0 731000.0 0.62 3290531.0 161000.0 0.13 0.5265 0.8365 3632558 CBKinase1_022655 CCc1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A18 compound treatment 3856019.0 651000.0 0.55 3681392.0 552000.0 0.44 0.6996 0.9939 3632559 CBKinase1_022656 CCC1(C)Cc2ccccc2-c3[nH]c4nnc(SCC(=O)Nc5ccc(OC)c(Cl)c5)n4c(=O)c31 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A19 compound treatment 3879240.0 675000.0 0.57 3056357.0 -73100.0 -0.06 0.3612 0.6314 3632560 CBKinase1_022657 Oc1ccccc1c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A20 compound treatment 3639016.0 434000.0 0.37 3094885.0 -34600.0 -0.03 0.2396 0.6521 3632561 CBKinase1_022658 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)NCC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A21 compound treatment 3520666.0 316000.0 0.27 3237050.0 108000.0 0.09 0.2492 0.8897 3632562 CBKinase1_022659 COc1ccccc1NC(=O)c2ccc(CSc3nnnn3c4ccccc4)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A22 compound treatment 3307639.0 103000.0 0.09 2787743.0 -342000.0 -0.27 -0.1311 -0.4586 3632563 CBKinase1_022660 COc1ccccc1N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A23 compound treatment 3139214.0 -65400.0 -0.06 2846466.0 -283000.0 -0.23 -0.1985 -0.8548 1657240 CBKinase1_022661 CCOC(=O)c1c(C)c(C)sc1NC(=O)CN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 A24 compound treatment 2620182.0 -584000.0 -0.49 2526656.0 -603000.0 -0.48 -0.6883 -0.9999 3632564 CBKinase1_022662 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccncc3)n2C)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B01 compound treatment 3867516.0 663000.0 0.56 3034785.0 -94700.0 -0.08 0.342 0.6062 3632565 CBKinase1_022663 O=C(NCc1ccco1)C2OCCc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B02 compound treatment 3794310.0 590000.0 0.5 3342940.0 213000.0 0.17 0.4721 0.8979 3632566 CBKinase1_022664 CCOc1cc(C)c(cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B03 compound treatment 3747906.0 543000.0 0.46 3270722.0 141000.0 0.11 0.4037 0.8554 3632567 CBKinase1_022665 [O-][N+](=O)c1ccccc1NCCNS(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B04 compound treatment 3535356.0 331000.0 0.28 1174784.0 -1950000.0 -1.56 -0.9044 -0.5714 3632568 CBKinase1_022666 Fc1ccc(cc1)C2CC(Nc3nc(NC(=O)CN4C(=O)c5ccccc5C4=O)nn23)c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B05 compound treatment 3752288.0 548000.0 0.46 3990759.0 861000.0 0.69 0.8121 0.9814 3632569 CBKinase1_022667 CNC(=O)CN(c1cc(ccc1OC)[N+](=O)[O-])S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B06 compound treatment 4233982.0 1030000.0 0.87 3313151.0 184000.0 0.15 0.7175 0.8148 3632570 CBKinase1_022668 COc1ccc(CCNC(=O)C2OCCc3ccccc23)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B07 compound treatment 4071942.0 867000.0 0.73 3529773.0 400000.0 0.32 0.7429 0.9308 3632571 CBKinase1_022669 CCOc1ccccc1CNCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B08 compound treatment 4046237.0 842000.0 0.71 3450431.0 321000.0 0.26 0.6829 0.905 3041279 CBKinase1_022670 CCCCN(Cc1cc2cc(OC)ccc2nc1O)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B09 compound treatment 3879968.0 675000.0 0.57 3658212.0 529000.0 0.42 0.7008 0.989 3632572 CBKinase1_022671 CCc1ccc(NC(=O)CSc2ncnc3sc4CC(C)CCc4c23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B10 compound treatment 3625660.0 421000.0 0.36 3170130.0 40700.0 0.03 0.2741 0.7685 3632573 CBKinase1_022672 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccccc3)c4ccc(Br)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B11 compound treatment 3935591.0 731000.0 0.62 3425045.0 296000.0 0.24 0.6026 0.9129 3632574 CBKinase1_022673 Ic1ccccc1C(=O)Nc2ccccc2C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B12 compound treatment 4083669.0 879000.0 0.74 4308395.0 1180000.0 0.94 1.1888 0.9931 3632575 CBKinase1_022674 COc1ccc(cc1N(CC(=O)Nc2cccc(C)c2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B13 mock treatment 4201340.0 997000.0 0.84 4266096.0 1140000.0 0.91 1.2351 0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B14 mock treatment 4329623.0 1130000.0 0.95 4260978.0 1130000.0 0.9 1.3087 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B15 compound treatment 4619197.0 1410000.0 1.19 3933533.0 804000.0 0.64 1.2969 0.9575 3632576 CBKinase1_022675 COc1ccccc1NC(=O)CNC(=O)c2ccc(OC)c(OC)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B16 compound treatment 4412767.0 1210000.0 1.02 4069106.0 940000.0 0.75 1.2502 0.9885 3632577 CBKinase1_022676 CSc1cccc(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B17 compound treatment 3845393.0 641000.0 0.54 3947818.0 818000.0 0.65 0.8434 0.9956 3632578 CBKinase1_022677 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B18 compound treatment 4389453.0 1180000.0 1.0 4173177.0 1040000.0 0.83 1.2949 0.9958 3632579 CBKinase1_022678 Cc1nnc(SCC(=O)Nc2ccc(cc2O)[N+](=O)[O-])s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B19 compound treatment 3684612.0 480000.0 0.4 3682151.0 553000.0 0.44 0.5978 0.9991 3632580 CBKinase1_022679 Oc1ccccc1c2nnc(SCC(=O)N3CCN(CC3)c4ccccc4)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B20 compound treatment 4119655.0 915000.0 0.77 3228144.0 98700.0 0.08 0.6014 0.7752 3632581 CBKinase1_022680 COc1ccc(NC(=O)CCC2COc3ccccc3O2)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B21 compound treatment 3760685.0 556000.0 0.47 3756945.0 627000.0 0.5 0.6853 0.9995 3632582 CBKinase1_022681 CCOc1ccc(c(C)c1C)S(=O)(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B22 compound treatment 3950360.0 746000.0 0.63 3699379.0 570000.0 0.45 0.766 0.9872 3632583 CBKinase1_022682 OCc1nc2ccccc2n1CC(O)Cn3ccc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B23 compound treatment 3886889.0 682000.0 0.58 3483496.0 354000.0 0.28 0.6065 0.9462 3632584 CBKinase1_022683 CC(C)(C)C1CCc2c(C#N)c(NC(=O)CN3CCOCC3)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 B24 compound treatment 3357771.0 153000.0 0.13 3113270.0 -16200.0 -0.01 0.0822 0.6334 3632585 CBKinase1_022684 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C01 compound treatment 2689327.0 -515000.0 -0.43 3100427.0 -29000.0 -0.02 -0.3237 -0.7437 3632586 CBKinase1_022685 Cc1ccc(cc1NC(=O)CSc2nnc(c3ccncc3)n2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C02 compound treatment 3595536.0 391000.0 0.33 3706056.0 577000.0 0.46 0.5581 0.9867 3632587 CBKinase1_022686 Cc1cc(C)cc(NC(=O)COc2ccc3cc(c4ccccc4)c(=O)oc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C03 compound treatment 3446621.0 242000.0 0.2 3154763.0 25300.0 0.02 0.1586 0.7732 3632588 CBKinase1_022687 CCC(Sc1nc(N)n[nH]1)C(=O)Nc2ccc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C04 compound treatment 2617682.0 -587000.0 -0.5 2808301.0 -321000.0 -0.26 -0.5311 -0.9529 3632589 CBKinase1_022688 CC(N1CCn2c(C1)nc3cc(NC(=O)COc4ccccc4)ccc23)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C05 compound treatment 2916138.0 -288000.0 -0.24 2742810.0 -387000.0 -0.31 -0.39 -0.9932 3632590 CBKinase1_022689 COC(=O)C(CC(=O)c1ccc(Cl)cc1)c2cc(=O)oc3cc(OC)ccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C06 compound treatment 2633895.0 -571000.0 -0.48 2660519.0 -469000.0 -0.37 -0.6047 -0.9922 1654987 CBKinase1_022690 Cc1ccc(NC(=O)COc2ccc3c(=O)c(coc3c2)c4ccccc4Cl)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C07 compound treatment 2961996.0 -243000.0 -0.2 2809273.0 -320000.0 -0.26 -0.3251 -0.994 3632591 CBKinase1_022691 COc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C08 compound treatment 2809183.0 -395000.0 -0.33 2930914.0 -199000.0 -0.16 -0.3477 -0.942 3632592 CBKinase1_022692 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2cc(C)ccc2OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C09 compound treatment 3137450.0 -67100.0 -0.06 2945013.0 -184000.0 -0.15 -0.144 -0.914 3632593 CBKinase1_022693 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C10 compound treatment 2977572.0 -227000.0 -0.19 2782233.0 -347000.0 -0.28 -0.3311 -0.9838 3632594 CBKinase1_022694 CC1CCc2c(C1)sc3ncn(CC(=O)Nc4ccccc4C(F)(F)F)c(=O)c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C11 mock treatment 3197703.0 -6890.0 -0.01 2816807.0 -313000.0 -0.25 -0.1803 -0.7234 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C12 mock treatment 3216826.0 12200.0 0.01 2879384.0 -250000.0 -0.2 -0.1336 -0.6696 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C13 compound treatment 3263181.0 58600.0 0.05 3064894.0 -64600.0 -0.05 -0.0014 -0.0202 3632595 CBKinase1_022695 Cc1cc(C)nc(Nc2n[nH]c(CSc3nc4ccccc4s3)n2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C14 compound treatment 3174592.0 -30000.0 -0.03 3434156.0 305000.0 0.24 0.1538 0.63 3632596 CBKinase1_022696 Nc1n[nH]c(SCC(=O)Nc2ccc(Br)cc2F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C15 mock treatment 3216046.0 11500.0 0.01 2927138.0 -202000.0 -0.16 -0.1072 -0.6636 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C16 mock treatment 3122347.0 -82200.0 -0.07 3157467.0 28000.0 0.02 -0.0333 -0.4564 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C17 compound treatment 3073903.0 -131000.0 -0.11 3129032.0 -418.0 0.0 -0.0782 -0.7092 3632597 CBKinase1_022697 CCOc1ccc(Oc2nc(NCC(C)C)nc(n2)N(C)C)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C18 compound treatment 3097250.0 -107000.0 -0.09 3000390.0 -129000.0 -0.1 -0.1368 -0.998 3632598 CBKinase1_022698 COc1ccccc1Nc2nc(N)nc(n2)c3oc4ccccc4c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C19 compound treatment 2758586.0 -446000.0 -0.38 2632039.0 -497000.0 -0.4 -0.5464 -0.9997 3632599 CBKinase1_022699 CS(=O)(=O)N(CC(=O)O)c1ccc(F)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C20 compound treatment 2870083.0 -335000.0 -0.28 2569732.0 -560000.0 -0.45 -0.515 -0.9756 1182113 CBKinase1_022700 COc1cc(OC)cc(c1)c2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C21 compound treatment 2486565.0 -718000.0 -0.61 2216910.0 -913000.0 -0.73 -0.9426 -0.9959 1984464 CBKinase1_022701 CN(CCCc1nc2ccccc2[nH]1)S(=O)(=O)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C22 compound treatment 2624988.0 -580000.0 -0.49 2313459.0 -816000.0 -0.65 -0.8056 -0.9901 3632600 CBKinase1_022702 COC(=O)c1ccc(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C23 compound treatment 2354829.0 -850000.0 -0.72 2193914.0 -936000.0 -0.75 -1.0341 -0.9998 3632601 CBKinase1_022703 Clc1ccc(cc1)n2nnnc2SCC(=O)Nc3cccc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 C24 compound treatment 2186341.0 -1020000.0 -0.86 2080861.0 -1050000.0 -0.84 -1.1983 -0.9999 3632602 CBKinase1_022704 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nnc(C)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D01 compound treatment 2691039.0 -514000.0 -0.43 2478565.0 -651000.0 -0.52 -0.6731 -0.996 3632603 CBKinase1_022705 CCOC(=O)C(O)(CC(=O)c1ccccc1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D02 compound treatment 2765961.0 -439000.0 -0.37 2463879.0 -666000.0 -0.53 -0.6367 -0.9845 3632604 CBKinase1_022706 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nc3ccccc3o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D03 compound treatment 3008587.0 -196000.0 -0.17 2536080.0 -593000.0 -0.47 -0.4513 -0.9008 3632605 CBKinase1_022707 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D04 compound treatment 2956139.0 -248000.0 -0.21 3204385.0 74900.0 0.06 -0.106 -0.4862 3632606 CBKinase1_022708 OC(=O)COc1ccccc1c2nc(c([nH]2)c3ccccc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D05 compound treatment 3168462.0 -36100.0 -0.03 3047838.0 -81600.0 -0.07 -0.0675 -0.9403 1489114 CBKinase1_022709 Cc1cccc(NC(=O)COc2ccc3c(=O)c(coc3c2)c4ccccc4)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D06 compound treatment 3333212.0 129000.0 0.11 3163504.0 34100.0 0.03 0.0959 0.8576 3632607 CBKinase1_022710 CC(=O)c1cccc(NC(=O)CSc2nc(C)cc(O)n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D07 compound treatment 3590031.0 385000.0 0.33 2882435.0 -247000.0 -0.2 0.0907 0.2386 1345798 CBKinase1_022711 Fc1ccccc1NC(=O)Cn2c(nc3ccccc23)c4cscn4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D08 compound treatment 3130633.0 -74000.0 -0.06 3123321.0 -6130.0 0.0 -0.0476 -0.7602 3632608 CBKinase1_022712 CCn1c(SCC(=O)Nc2ccc(OC)c(Cl)c2)nnc1c3ccccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D09 compound treatment 3526649.0 322000.0 0.27 2856379.0 -273000.0 -0.22 0.0382 0.1097 3041510 CBKinase1_022713 Cc1cccc(OCC(=O)Nc2ccc3n4CCN(Cc4nc3c2)c5ccccc5)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D10 compound treatment 3731464.0 527000.0 0.44 3257995.0 129000.0 0.1 0.3867 0.8479 3632609 CBKinase1_022714 COc1cc(CO)ccc1OCC(=O)Nc2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D11 mock treatment 3760967.0 556000.0 0.47 3495062.0 366000.0 0.29 0.5379 0.9737 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D12 mock treatment 3590949.0 386000.0 0.33 3405509.0 276000.0 0.22 0.386 0.9817 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D13 compound treatment 3651498.0 447000.0 0.38 3281972.0 153000.0 0.12 0.3525 0.89 3632610 CBKinase1_022715 CC(C)(C)C1CCc2c(C1)sc3ncn(CC(=O)NCc4ccco4)c(=O)c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D14 compound treatment 3468028.0 263000.0 0.22 3101579.0 -27900.0 -0.02 0.1414 0.6333 3632611 CBKinase1_022716 COc1ccc2nc(O)c(CN(C)S(=O)(=O)C)cc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D15 mock treatment 3569539.0 365000.0 0.31 3301748.0 172000.0 0.14 0.3148 0.9338 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D16 mock treatment 3447042.0 242000.0 0.2 3531416.0 402000.0 0.32 0.3712 0.9765 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D17 compound treatment 3207779.0 3190.0 0.0 3407161.0 278000.0 0.22 0.1584 0.7156 3632612 CBKinase1_022717 Cc1sc2ncn(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c(=O)c2c1c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D18 compound treatment 3479504.0 275000.0 0.23 3198361.0 68900.0 0.05 0.2028 0.851 3632613 CBKinase1_022718 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2SC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D19 compound treatment 3060943.0 -144000.0 -0.12 2760385.0 -369000.0 -0.29 -0.2937 -0.9231 3632614 CBKinase1_022719 CCOc1ccc(cc1)c2cn(nc2N)S(=O)(=O)c3cccc4nsnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D20 compound treatment 3296596.0 92000.0 0.08 3413594.0 284000.0 0.23 0.215 0.8981 3632615 CBKinase1_022720 COc1ccc(NC(=O)COc2ccccc2CO)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D21 compound treatment 2771802.0 -433000.0 -0.37 2468395.0 -661000.0 -0.53 -0.6307 -0.9839 3632616 CBKinase1_022721 Cc1ccccc1c2nnc(SCC(=O)Nc3ccccc3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D22 compound treatment 2791512.0 -413000.0 -0.35 2581254.0 -548000.0 -0.44 -0.5553 -0.9937 1868346 CBKinase1_022722 Cc1ccc2c(CC(=O)NCc3ccco3)coc2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D23 compound treatment 2544171.0 -660000.0 -0.56 2235754.0 -894000.0 -0.71 -0.8976 -0.9926 3632617 CBKinase1_022723 Cc1ncc([N+](=O)[O-])n1Cc2nnc(S)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 D24 compound treatment 2210276.0 -994000.0 -0.84 2143592.0 -986000.0 -0.79 -1.1487 -0.9995 3632618 CBKinase1_022724 CC(Oc1ccc(cc1)c2ccccc2)C(=O)Nc3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E01 mock treatment 1223249.0 -1980000.0 -1.67 939793.0 -2190000.0 -1.75 -2.4158 -0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E02 mock treatment 1942773.0 -1260000.0 -1.06 1242060.0 -1890000.0 -1.5 -1.8163 -0.9856 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E03 compound treatment 1503998.0 -1700000.0 -1.43 1312352.0 -1820000.0 -1.45 -2.0384 -1.0 3632619 CBKinase1_022725 COc1ccc(OC)c(NC(=O)CNC(=O)c2ccccc2F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E04 compound treatment 1619814.0 -1580000.0 -1.34 1716251.0 -1410000.0 -1.13 -1.7417 -0.9964 3632620 CBKinase1_022726 COc1ccc(CCNc2nc(C)cc(C)n2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E05 compound treatment 1777745.0 -1430000.0 -1.2 1577022.0 -1550000.0 -1.24 -1.726 -0.9999 3632621 CBKinase1_022727 Cc1ccc(NC(=O)c2ccc(OCC(=O)Nc3ccc(Oc4ccccc4)cc3)cc2)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E06 compound treatment 2058883.0 -1150000.0 -0.97 1897279.0 -1230000.0 -0.98 -1.3778 -1.0 3632622 CBKinase1_022728 COc1ccc(Cl)cc1NC(=O)CSc2nnc([nH]2)c3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E07 compound treatment 2083918.0 -1120000.0 -0.95 2067191.0 -1060000.0 -0.85 -1.2671 -0.9985 3632623 CBKinase1_022729 CCN(CC(=O)Nc1cccc(OC)c1)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E08 compound treatment 2140996.0 -1060000.0 -0.9 2366353.0 -763000.0 -0.61 -1.0645 -0.9821 3632624 CBKinase1_022730 CCOc1ccccc1CNCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E09 mock treatment 2757041.0 -448000.0 -0.38 2488684.0 -641000.0 -0.51 -0.6281 -0.9889 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E10 mock treatment 2468063.0 -737000.0 -0.62 2546278.0 -583000.0 -0.46 -0.768 -0.9898 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E11 compound treatment 2237411.0 -967000.0 -0.82 2177977.0 -951000.0 -0.76 -1.1131 -0.9993 3632625 CBKinase1_022731 CCC(=O)N1CCN(CC1)c2ccc(Cl)cc2NC(=O)COc3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E12 compound treatment 2553128.0 -651000.0 -0.55 2482346.0 -647000.0 -0.52 -0.7533 -0.9995 3632626 CBKinase1_022732 Clc1ccccc1COC(=O)Cn2nnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E13 compound treatment 2491192.0 -713000.0 -0.6 2224798.0 -905000.0 -0.72 -0.9354 -0.996 3632627 CBKinase1_022733 NC(=O)CN(c1ccccc1)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E14 compound treatment 2534763.0 -670000.0 -0.56 2214482.0 -915000.0 -0.73 -0.9152 -0.992 3632628 CBKinase1_022734 COc1cc(ccc1Br)S(=O)(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E15 compound treatment 2575284.0 -629000.0 -0.53 2471096.0 -658000.0 -0.52 -0.7464 -1.0 3038415 CBKinase1_022735 Oc1nc2ccccc2cc1CN(C(=O)c3cccc(Cl)c3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E16 compound treatment 2493319.0 -711000.0 -0.6 2366219.0 -763000.0 -0.61 -0.8544 -1.0 3632629 CBKinase1_022736 COCc1cnc(Nc2nc3ccccc3o2)nc1C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E17 mock treatment 2579799.0 -625000.0 -0.53 2867815.0 -262000.0 -0.21 -0.5201 -0.9177 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E18 mock treatment 2541917.0 -663000.0 -0.56 2860245.0 -269000.0 -0.21 -0.547 -0.9135 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E19 compound treatment 2466021.0 -739000.0 -0.62 2327613.0 -802000.0 -0.64 -0.8924 -0.9999 3632630 CBKinase1_022737 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccc(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E20 compound treatment 2480638.0 -724000.0 -0.61 1945439.0 -1180000.0 -0.94 -1.0991 -0.9778 3632631 CBKinase1_022738 O=C(CSc1nc(nc(n1)N2CCCCC2)N3CCCCC3)NC4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E21 compound treatment 2227344.0 -977000.0 -0.82 1998287.0 -1130000.0 -0.9 -1.2204 -0.999 3632632 CBKinase1_022739 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E22 compound treatment 2205798.0 -999000.0 -0.84 2028432.0 -1100000.0 -0.88 -1.2163 -0.9998 3632633 CBKinase1_022740 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cccc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E23 compound treatment 2174673.0 -1030000.0 -0.87 2021399.0 -1110000.0 -0.88 -1.2388 -1.0 1868230 CBKinase1_022741 COc1ccc(NC(=O)Cc2coc3cc(C)cc(C)c23)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 E24 compound treatment 1901675.0 -1300000.0 -1.1 1986721.0 -1140000.0 -0.91 -1.4212 -0.9956 3632634 CBKinase1_022742 Cc1cccc(NS(=O)(=O)c2cc(ccc2Cl)C(=O)Nc3ccccc3C(=O)N4CCOCC4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F01 mock treatment 2017076.0 -1190000.0 -1.0 894272.0 -2240000.0 -1.78 -1.968 -0.9629 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F02 mock treatment 2395860.0 -809000.0 -0.68 1900305.0 -1230000.0 -0.98 -1.1751 -0.9843 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F03 compound treatment 1516626.0 -1690000.0 -1.42 1514736.0 -1610000.0 -1.29 -1.9168 -0.9987 3632635 CBKinase1_022743 Cn1nc(nc1Oc2ccccc2C(=O)N3CCOCC3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F04 compound treatment 1813455.0 -1390000.0 -1.17 1301415.0 -1830000.0 -1.46 -1.86 -0.9942 3632636 CBKinase1_022744 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cc(Cl)cc(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F05 compound treatment 1664588.0 -1540000.0 -1.3 1419605.0 -1710000.0 -1.36 -1.8822 -0.9997 3632637 CBKinase1_022745 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3cc(Cl)ccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F06 compound treatment 1976605.0 -1230000.0 -1.04 2686481.0 -443000.0 -0.35 -0.9821 -0.8974 3632638 CBKinase1_022746 Cc1ccc(NC(=O)C2CC(=O)n3ncnc3N2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F07 compound treatment 1775222.0 -1430000.0 -1.21 1843175.0 -1290000.0 -1.03 -1.5775 -0.9967 3632639 CBKinase1_022747 COC(=O)c1ccccc1NC(=O)C(C)NS(=O)(=O)c2cc(Cl)ccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F08 compound treatment 1993495.0 -1210000.0 -1.02 1957213.0 -1170000.0 -0.93 -1.383 -0.999 3632640 CBKinase1_022748 Fc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F09 mock treatment 1980259.0 -1220000.0 -1.03 2008512.0 -1120000.0 -0.89 -1.362 -0.9974 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F10 mock treatment 2272220.0 -932000.0 -0.79 2012442.0 -1120000.0 -0.89 -1.1856 -0.9981 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F11 compound treatment 2315740.0 -889000.0 -0.75 2141619.0 -988000.0 -0.79 -1.0869 -0.9997 3632641 CBKinase1_022749 COc1ccccc1NC(=O)COc2ccc(CO)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F12 compound treatment 2392176.0 -812000.0 -0.69 2276627.0 -853000.0 -0.68 -0.9652 -1.0 3632642 CBKinase1_022750 CCn1c(SCC(=O)Nc2ccc(F)cc2)nnc1c3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F13 compound treatment 2196732.0 -1010000.0 -0.85 1929477.0 -1200000.0 -0.96 -1.2774 -0.9983 3632643 CBKinase1_022751 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccccc2C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F14 compound treatment 2225335.0 -979000.0 -0.83 2254808.0 -875000.0 -0.7 -1.077 -0.9964 3632644 CBKinase1_022752 [O-][N+](=O)c1ccc(cc1)C(=O)OCc2nc3ccccc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F15 compound treatment 1916634.0 -1290000.0 -1.09 2125866.0 -1000000.0 -0.8 -1.3338 -0.9887 3632645 CBKinase1_022753 Brc1ccc(Oc2ccc(NC(=O)CN3C(=O)C4C(C5C=CC4C6CC65)C3=O)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F16 compound treatment 2023733.0 -1180000.0 -1.0 2166209.0 -963000.0 -0.77 -1.2472 -0.9917 1749577 CBKinase1_022754 COc1ccccc1NC(=O)Cn2nnc(n2)c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F17 mock treatment 2152866.0 -1050000.0 -0.89 2247062.0 -882000.0 -0.7 -1.1246 -0.9934 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F18 mock treatment 2053113.0 -1150000.0 -0.97 1935982.0 -1190000.0 -0.95 -1.3594 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F19 compound treatment 1877530.0 -1330000.0 -1.12 2624802.0 -505000.0 -0.4 -1.0759 -0.9046 3632646 CBKinase1_022755 Oc1ccccc1c2nnc(SCC(=O)Nc3ccc(cc3)N4CCOCC4)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F20 compound treatment 1672308.0 -1530000.0 -1.29 1946692.0 -1180000.0 -0.94 -1.5805 -0.988 3632647 CBKinase1_022756 NC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F21 compound treatment 1852202.0 -1350000.0 -1.14 2364007.0 -765000.0 -0.61 -1.238 -0.957 3632648 CBKinase1_022757 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F22 compound treatment 2355970.0 -849000.0 -0.72 2180589.0 -949000.0 -0.76 -1.0409 -0.9996 3632649 CBKinase1_022758 COc1ccccc1C(=O)N(Cc2nnc3c4ccccc4c(C)nn23)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F23 compound treatment 2222121.0 -982000.0 -0.83 2058017.0 -1070000.0 -0.85 -1.1898 -0.9999 3632650 CBKinase1_022759 COc1ccccc1NC(=O)CNC(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 F24 compound treatment 2171405.0 -1030000.0 -0.87 2178316.0 -951000.0 -0.76 -1.1523 -0.9976 3632651 CBKinase1_022760 COc1ccc(NC(=O)CS(=O)(=O)c2ccc3ccccc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G01 compound treatment 2548797.0 -656000.0 -0.55 1894418.0 -1240000.0 -0.98 -1.0872 -0.9628 3632652 CBKinase1_022761 CCC(=O)Nc1ccc(OCc2nc3ccccc3s2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G02 compound treatment 2732924.0 -472000.0 -0.4 2543488.0 -586000.0 -0.47 -0.6116 -0.9968 3632653 CBKinase1_022762 COc1ccc2[nH]c(SCC(=O)Nc3ccc(I)cc3)nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G03 mock treatment 2651256.0 -553000.0 -0.47 3072160.0 -57300.0 -0.05 -0.3623 -0.7726 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G04 mock treatment 2805353.0 -399000.0 -0.34 2429097.0 -700000.0 -0.56 -0.6328 -0.9707 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G05 compound treatment 2816540.0 -388000.0 -0.33 2966192.0 -163000.0 -0.13 -0.3235 -0.9183 3632654 CBKinase1_022763 Cc1csc(SCC(=O)Nc2ccc3OCCOc3c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G06 compound treatment 2701630.0 -503000.0 -0.42 2789534.0 -340000.0 -0.27 -0.4916 -0.9765 3632655 CBKinase1_022764 COC(=O)c1cccc(NC(=O)CSc2nc3ccccc3s2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G07 compound treatment 3031633.0 -173000.0 -0.15 2897311.0 -232000.0 -0.19 -0.234 -0.9931 3632656 CBKinase1_022765 COc1ccc(OC)c(NC(=O)COc2ccc3c(=O)c(c4ccc(OC)c(OC)c4)c(oc3c2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G08 compound treatment 3122935.0 -81700.0 -0.07 2890963.0 -238000.0 -0.19 -0.1831 -0.9057 3632657 CBKinase1_022766 CC(C)(CO)NCc1ccc(o1)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G09 compound treatment 3393755.0 189000.0 0.16 3025627.0 -104000.0 -0.08 0.0543 0.3022 3632658 CBKinase1_022767 COC(=O)c1ccc(NC(=O)CN2C(=O)C3C4CC(C(C4)C3C2=O)c5ccccc5)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G10 compound treatment 3167889.0 -36700.0 -0.03 2952391.0 -177000.0 -0.14 -0.1217 -0.8422 3632659 CBKinase1_022768 CCOc1cc(c(C)cc1C)S(=O)(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G11 compound treatment 3477092.0 273000.0 0.23 2976476.0 -153000.0 -0.12 0.0763 0.2933 3632660 CBKinase1_022769 Cc1c(NC(=O)CS(=O)(=O)c2ccccc2)c(=O)n(c3ccccc3)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G12 compound treatment 2929535.0 -275000.0 -0.23 2917486.0 -212000.0 -0.17 -0.2835 -0.9879 3632661 CBKinase1_022770 [O-][N+](=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G13 compound treatment 2969786.0 -235000.0 -0.2 2782162.0 -347000.0 -0.28 -0.3358 -0.9865 3632662 CBKinase1_022771 COc1ccccc1n2nnnc2SCC(=O)Nc3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G14 compound treatment 2896154.0 -308000.0 -0.26 2746397.0 -383000.0 -0.31 -0.3999 -0.9968 3632663 CBKinase1_022772 Cn1cccc1CNCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G15 compound treatment 3094682.0 -110000.0 -0.09 2781944.0 -348000.0 -0.28 -0.2614 -0.895 3632664 CBKinase1_022773 COc1ccc(NC(=O)C(=O)NCC(=O)Nc2ccc(C)c(Cl)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G16 compound treatment 3039618.0 -165000.0 -0.14 2780158.0 -349000.0 -0.28 -0.2953 -0.9486 3632665 CBKinase1_022774 Clc1ccc(cc1C(=O)Nc2ccc(cc2)C(=O)NCC3CCCO3)n4cnnc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G17 compound treatment 3211983.0 7390.0 0.01 3049639.0 -79800.0 -0.06 -0.0406 -0.6348 3632666 CBKinase1_022775 CCOc1ccc(C)cc1S(=O)(=O)n2nnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G18 compound treatment 2852567.0 -352000.0 -0.3 2964855.0 -165000.0 -0.13 -0.3027 -0.9326 3632667 CBKinase1_022776 COC(=O)c1ccc(Cl)c(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G19 mock treatment 2737069.0 -468000.0 -0.39 2741762.0 -388000.0 -0.31 -0.4973 -0.9927 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G20 mock treatment 2911472.0 -293000.0 -0.25 1896005.0 -1230000.0 -0.98 -0.87 -0.8582 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G21 compound treatment 2702258.0 -502000.0 -0.42 2245299.0 -884000.0 -0.7 -0.7979 -0.9704 3632668 CBKinase1_022777 COc1ccc(NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G22 compound treatment 2699826.0 -505000.0 -0.43 2082659.0 -1050000.0 -0.83 -0.891 -0.9512 3632669 CBKinase1_022778 CC(=O)c1ccc(NC(=O)CSc2nc(N)cc(O)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G23 compound treatment 2497626.0 -707000.0 -0.6 2080264.0 -1050000.0 -0.84 -1.013 -0.9863 3632670 CBKinase1_022779 CC(Oc1ccc(cc1)C(=O)Nc2cccc(C)c2C)C(=O)Nc3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 G24 compound treatment 2074510.0 -1130000.0 -0.95 2280538.0 -849000.0 -0.68 -1.1525 -0.9859 3632671 CBKinase1_022780 O=C(CCSc1nc(cs1)c2ccccc2)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H01 compound treatment 2261872.0 -943000.0 -0.8 2398069.0 -731000.0 -0.58 -0.9745 -0.9883 3632672 CBKinase1_022781 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(Cl)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H02 compound treatment 2917537.0 -287000.0 -0.24 2974147.0 -155000.0 -0.12 -0.2587 -0.9515 3632673 CBKinase1_022782 COc1ccc(NC(=O)C(=O)NCC(=O)Nc2cccc(c2)C(F)(F)F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H03 mock treatment 2945747.0 -259000.0 -0.22 2990115.0 -139000.0 -0.11 -0.2329 -0.9508 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H04 mock treatment 3384120.0 180000.0 0.15 3402114.0 273000.0 0.22 0.2608 0.9844 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H05 compound treatment 2983583.0 -221000.0 -0.19 3049899.0 -79600.0 -0.06 -0.1767 -0.8971 3632674 CBKinase1_022783 Cc1ccccc1NC(=O)CSc2ncnc3c2sc4nc(N5CCOCC5)c6CCCCc6c43 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H06 compound treatment 3177029.0 -27600.0 -0.02 2890528.0 -239000.0 -0.19 -0.1511 -0.7876 3632675 CBKinase1_022784 OC1(CC(=O)c2ccccc2[N+](=O)[O-])C(=O)N(Cc3ccccc3)c4ccc(Br)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H07 compound treatment 3358085.0 153000.0 0.13 3365012.0 236000.0 0.19 0.2243 0.9835 3632676 CBKinase1_022785 COc1ccc(OC)c(NC(=O)CSc2nnc([nH]2)c3ccncc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H08 compound treatment 3233695.0 29100.0 0.02 3128027.0 -1420.0 0.0 0.0166 0.6737 3632677 CBKinase1_022786 Cc1[nH]c2nc(NCc3cccc(c3)[N+](=O)[O-])nn2c(=O)c1Cc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H09 compound treatment 3290609.0 86000.0 0.07 2964358.0 -165000.0 -0.13 -0.0417 -0.2778 3632678 CBKinase1_022787 COc1ccc(Cl)cc1NC(=O)Cn2cnc3sc4CC(C)CCc4c3c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H10 compound treatment 3234517.0 29900.0 0.03 3001950.0 -128000.0 -0.1 -0.054 -0.5158 3632679 CBKinase1_022788 COc1ccc(OC)c(NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(C)c3C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H11 compound treatment 3370655.0 166000.0 0.14 3304998.0 176000.0 0.14 0.198 1.0 3632680 CBKinase1_022789 Nc1n[nH]c(SCC(=O)Nc2ccccc2C(F)(F)F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H12 compound treatment 3424128.0 220000.0 0.19 3323410.0 194000.0 0.15 0.2403 0.996 3632681 CBKinase1_022790 C(CSc1nnc2n(c3ccccc3)c4ccccc4n12)Oc5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H13 compound treatment 3444048.0 239000.0 0.2 3428359.0 299000.0 0.24 0.3113 0.9966 3632682 CBKinase1_022791 COc1ccccc1NC(=O)CNC(=O)c2ccc(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H14 compound treatment 3711828.0 507000.0 0.43 3207886.0 78400.0 0.06 0.3467 0.8019 3632683 CBKinase1_022792 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H15 compound treatment 3435464.0 231000.0 0.19 3119049.0 -10400.0 -0.01 0.1318 0.6764 3632684 CBKinase1_022793 CCOc1cc(ccc1Br)S(=O)(=O)n2nnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H16 compound treatment 3412366.0 208000.0 0.18 3351598.0 222000.0 0.18 0.2491 1.0 1757007 CBKinase1_022794 Cn1c(SCC(=O)N2c3ccccc3Sc4ccccc24)nnc1c5ccco5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H17 compound treatment 3429454.0 225000.0 0.19 3297897.0 168000.0 0.13 0.2291 0.9857 3632685 CBKinase1_022795 Cc1cc(C)nc(SCC(=O)Nc2ccnc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H18 compound treatment 3408193.0 204000.0 0.17 2258075.0 -871000.0 -0.69 -0.3697 -0.5167 1570419 CBKinase1_022796 Cc1ccc(NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(C)c3C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H19 mock treatment 3014363.0 -190000.0 -0.16 2907377.0 -222000.0 -0.18 -0.2386 -0.9988 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H20 mock treatment 3085593.0 -119000.0 -0.1 2901478.0 -228000.0 -0.18 -0.1995 -0.9609 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H21 compound treatment 3343169.0 139000.0 0.12 2396543.0 -733000.0 -0.58 -0.3304 -0.5546 3632686 CBKinase1_022797 Cc1cccc(C)c1NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H22 compound treatment 3476016.0 271000.0 0.23 2342500.0 -787000.0 -0.63 -0.2816 -0.4218 3632687 CBKinase1_022798 COC(=O)c1cc(NC(=O)CSc2nc(C)cc(C)n2)cc(c1)C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H23 compound treatment 2216740.0 -988000.0 -0.83 2452637.0 -677000.0 -0.54 -0.9706 -0.9779 3632688 CBKinase1_022799 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 H24 compound treatment 2572561.0 -632000.0 -0.53 1793267.0 -1340000.0 -1.06 -1.13 -0.9488 3632689 CBKinase1_022800 COc1ccc(cc1Cl)S(=O)(=O)N(CC(=O)O)C2CCCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I01 compound treatment 2563372.0 -641000.0 -0.54 2568173.0 -561000.0 -0.45 -0.6988 -0.9956 3632690 CBKinase1_022801 COc1ccc(OC)c(NC(=O)COc2ccc3c(=O)c(c4ccccc4OC)c(oc3c2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I02 compound treatment 2858739.0 -346000.0 -0.29 3149381.0 19900.0 0.02 -0.195 -0.6676 3632691 CBKinase1_022802 Clc1ccc2sc(SCC(=O)Nc3ccc(I)cc3)nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I03 compound treatment 3198211.0 -6380.0 -0.01 3069696.0 -59800.0 -0.05 -0.0375 -0.782 3632692 CBKinase1_022803 CNC(=O)CN(c1ccccc1C)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I04 compound treatment 3208258.0 3670.0 0.0 3030246.0 -99200.0 -0.08 -0.0537 -0.6789 3632693 CBKinase1_022804 CC1(C)CC2=C(C(=O)C1)C(NC(=O)C3CC3)(C(=O)N2Cc4cccnc4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I05 mock treatment 3475170.0 271000.0 0.23 3477830.0 348000.0 0.28 0.3577 0.9953 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I06 mock treatment 3124622.0 -80000.0 -0.07 3428021.0 299000.0 0.24 0.1206 0.4875 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I07 compound treatment 3162786.0 -41800.0 -0.04 3289753.0 160000.0 0.13 0.0654 0.4935 3632694 CBKinase1_022805 COc1ccc(NC(=O)CNC(=O)c2ccccc2F)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I08 compound treatment 3645785.0 441000.0 0.37 3218615.0 89200.0 0.07 0.3134 0.8272 3632695 CBKinase1_022806 CCCN(Cc1cc2cccc(C)c2nc1O)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I09 compound treatment 3594834.0 390000.0 0.33 3297886.0 168000.0 0.13 0.3277 0.9218 3632696 CBKinase1_022807 COCCCNC(=O)c1ccc(cc1)c2nc3ccccc3nc2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I10 compound treatment 3381548.0 177000.0 0.15 3312858.0 183000.0 0.15 0.2089 0.9999 3632697 CBKinase1_022808 CC(C)CNc1nc(Oc2ccc(O)nn2)nc(n1)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I11 compound treatment 3399524.0 195000.0 0.16 3246733.0 117000.0 0.09 0.1824 0.9642 3632698 CBKinase1_022809 OC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)Nc3ccc(Cl)c(Cl)c3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I12 compound treatment 3232820.0 28200.0 0.02 3265216.0 136000.0 0.11 0.0934 0.8425 1868190 CBKinase1_022810 Cc1cc(C)c2c(CC(=O)N(CC#N)CC#N)coc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I13 compound treatment 3420180.0 216000.0 0.18 3348816.0 219000.0 0.17 0.2522 0.9998 3632699 CBKinase1_022811 COc1cc(C)c(Cl)cc1S(=O)(=O)NCC2CCCO2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I14 compound treatment 3423761.0 219000.0 0.18 3296605.0 167000.0 0.13 0.2249 0.9871 3632700 CBKinase1_022812 OCc1cc(Br)ccc1OCC(=O)Nc2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I15 compound treatment 3656264.0 452000.0 0.38 3424998.0 296000.0 0.24 0.436 0.9733 3632701 CBKinase1_022813 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I16 compound treatment 3354327.0 150000.0 0.13 3339597.0 210000.0 0.17 0.2077 0.9903 3632702 CBKinase1_022814 CCN(CC(=O)Nc1cccc2ccccc12)S(=O)(=O)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I17 compound treatment 3453445.0 249000.0 0.21 3253684.0 124000.0 0.1 0.2184 0.9412 3632703 CBKinase1_022815 COc1ccc(OC)c(NC(=O)COc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I18 compound treatment 3526005.0 321000.0 0.27 3368101.0 239000.0 0.19 0.3262 0.985 3632704 CBKinase1_022816 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I19 compound treatment 3100591.0 -104000.0 -0.09 3186401.0 57000.0 0.05 -0.0299 -0.3031 3632705 CBKinase1_022817 CCCC(C)n1nc(O)c2C(SCC(=O)Nc21)c3cccc(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I20 compound treatment 3237139.0 32500.0 0.03 2787905.0 -342000.0 -0.27 -0.1731 -0.6326 3632706 CBKinase1_022818 OC(=O)c1cccc(CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I21 mock treatment 3533260.0 329000.0 0.28 2652214.0 -477000.0 -0.38 -0.0729 -0.155 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I22 mock treatment 2521382.0 -683000.0 -0.58 2483034.0 -646000.0 -0.52 -0.7718 -0.9984 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I23 compound treatment 2050621.0 -1150000.0 -0.97 2696414.0 -433000.0 -0.35 -0.9323 -0.9028 3632707 CBKinase1_022819 CC(=O)c1ccccc1OCC(O)CN2CCN(CC2)c3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 I24 compound treatment 2604792.0 -600000.0 -0.51 2359604.0 -770000.0 -0.61 -0.7916 -0.9954 3632708 CBKinase1_022820 CCOc1ccc(C)cc1S(=O)(=O)Nc2ccc(Cl)cn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J01 compound treatment 3004873.0 -200000.0 -0.17 2552600.0 -577000.0 -0.46 -0.4442 -0.9072 3632709 CBKinase1_022821 COc1ccc(OCC(=O)Nc2ccccc2OC(F)F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J02 compound treatment 3299158.0 94600.0 0.08 2710590.0 -419000.0 -0.33 -0.1797 -0.5234 3632710 CBKinase1_022822 COC(=O)Cc1c(C)[nH]c2nc(nn2c1=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J03 compound treatment 3519379.0 315000.0 0.27 3078314.0 -51100.0 -0.04 0.1589 0.5916 3632711 CBKinase1_022823 Cc1ccc2n(C)c3nc(SCCN4CCCCC4)nnc3c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J04 compound treatment 3398775.0 194000.0 0.16 2950061.0 -179000.0 -0.14 0.0147 0.0677 3632712 CBKinase1_022824 CCCN1C(=O)C(NS(=O)(=O)c2ccc(NC(=O)C)cc2)(C3=C1CC(C)(C)CC3=O)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J05 mock treatment 3877016.0 672000.0 0.57 3291542.0 162000.0 0.13 0.4924 0.8465 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J06 mock treatment 3314366.0 110000.0 0.09 3178919.0 49500.0 0.04 0.0934 0.9276 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J07 compound treatment 3643174.0 439000.0 0.37 3432691.0 303000.0 0.24 0.4325 0.9787 3632713 CBKinase1_022825 Cc1cccc(OCC(=O)Nc2ccccc2N3CCN(CC3)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J08 compound treatment 3653959.0 449000.0 0.38 3424768.0 295000.0 0.24 0.4345 0.9737 3632714 CBKinase1_022826 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)C(F)(F)F)c2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J09 compound treatment 3801656.0 597000.0 0.5 3211166.0 81700.0 0.07 0.4022 0.792 3632715 CBKinase1_022827 Fc1ccc(NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J10 compound treatment 3918562.0 714000.0 0.6 3256970.0 128000.0 0.1 0.4977 0.8149 3632716 CBKinase1_022828 COc1ccccc1NC(=O)Cn2nnc(n2)c3ccc(cc3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J11 compound treatment 3763753.0 559000.0 0.47 3284015.0 155000.0 0.12 0.4206 0.8629 3632717 CBKinase1_022829 Cc1ccc(C)c(NC(=O)c2ccc(OCC(=O)Nc3ccccc3C)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J12 compound treatment 3762603.0 558000.0 0.47 3583358.0 454000.0 0.36 0.5886 0.9916 3632718 CBKinase1_022830 CN(Cc1cc2ccccc2nc1O)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J13 compound treatment 3475468.0 271000.0 0.23 3436140.0 307000.0 0.24 0.3344 0.9994 3632719 CBKinase1_022831 CCN(CC(=O)Nc1cccc(OC)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J14 compound treatment 4023114.0 819000.0 0.69 3662162.0 533000.0 0.42 0.7884 0.9727 3632720 CBKinase1_022832 COc1cccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J15 compound treatment 4061782.0 857000.0 0.72 3480217.0 351000.0 0.28 0.709 0.9145 3632721 CBKinase1_022833 Fc1cccc(NC(=O)CSc2nccc(=O)[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J16 compound treatment 4025075.0 820000.0 0.69 3545963.0 417000.0 0.33 0.7241 0.9434 3632722 CBKinase1_022834 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(Br)cc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J17 compound treatment 4164504.0 960000.0 0.81 3647608.0 518000.0 0.41 0.8646 0.9512 3632723 CBKinase1_022835 COc1ccc(Cl)cc1NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J18 compound treatment 4264539.0 1060000.0 0.89 3715602.0 586000.0 0.47 0.9625 0.9542 3632724 CBKinase1_022836 O=C(CSc1nnnn1c2ccccc2)Nc3cccc4nsnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J19 compound treatment 3884645.0 680000.0 0.57 3269358.0 140000.0 0.11 0.4845 0.829 3632725 CBKinase1_022837 Nc1n[nH]c(SCC(=O)Nc2ccc(Br)cc2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J20 compound treatment 3814213.0 610000.0 0.51 2791679.0 -338000.0 -0.27 0.1732 0.2985 3632726 CBKinase1_022838 CC(=O)c1cccc(c1)N(CC(=O)O)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J21 mock treatment 3403979.0 199000.0 0.17 2575755.0 -554000.0 -0.44 -0.1931 -0.4089 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J22 mock treatment 3650154.0 446000.0 0.38 2839297.0 -290000.0 -0.23 0.1022 0.2316 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J23 compound treatment 2975811.0 -229000.0 -0.19 3206762.0 77300.0 0.06 -0.0929 -0.4585 3632727 CBKinase1_022839 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc3OCCOc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 J24 compound treatment 2189805.0 -1010000.0 -0.86 2384820.0 -745000.0 -0.59 -1.0249 -0.984 3632728 CBKinase1_022840 Cc1csc2nc(SCC(=O)Nc3ccc(C)c(Cl)c3)[nH]c(=O)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K01 compound treatment 1560389.0 -1640000.0 -1.39 1663417.0 -1470000.0 -1.17 -1.8069 -0.9964 3632729 CBKinase1_022841 COC(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3F)n2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K02 compound treatment 2418144.0 -786000.0 -0.66 3763658.0 634000.0 0.51 -0.1116 -0.1339 3632730 CBKinase1_022842 Cc1c(C)c(NC(=O)Cn2cnc3sc4CCCCc4c3c2=O)ccc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K03 compound treatment 3087725.0 -117000.0 -0.1 3581478.0 452000.0 0.36 0.1851 0.4954 1868231 CBKinase1_022843 COc1ccc(NC(=O)Cc2coc3c(C)c(C)ccc23)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K04 compound treatment 3707141.0 503000.0 0.42 4005659.0 876000.0 0.7 0.7936 0.9714 3124037 CBKinase1_022844 O=C(CC1Nc2cccc3cccc(NC1=O)c23)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K05 compound treatment 3209753.0 5160.0 0.0 3740623.0 611000.0 0.49 0.3475 0.7134 3632731 CBKinase1_022845 CSc1nc(SCC(=O)Nc2cccc(C)c2)c3c4CCCCc4sc3n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K06 compound treatment 3041130.0 -163000.0 -0.14 3283079.0 154000.0 0.12 -0.0109 -0.0592 3632732 CBKinase1_022846 COC(=O)c1cc(NC(=O)CSC2=NCCS2)cc(c1)C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K07 mock treatment 3134253.0 -70300.0 -0.06 3511856.0 382000.0 0.3 0.1736 0.559 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K08 mock treatment 2704641.0 -500000.0 -0.42 3404917.0 275000.0 0.22 -0.1429 -0.3006 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K09 compound treatment 3017764.0 -187000.0 -0.16 3263958.0 135000.0 0.11 -0.0356 -0.1869 3632733 CBKinase1_022847 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)C3CCCC3)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K10 compound treatment 2719021.0 -486000.0 -0.41 3364378.0 235000.0 0.19 -0.1572 -0.3491 3632734 CBKinase1_022848 Cc1ccc(NC(=O)COc2ccc3cc(c4ccc(F)cc4)c(=O)oc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K11 compound treatment 2956862.0 -248000.0 -0.21 3209795.0 80300.0 0.06 -0.1025 -0.4689 3632735 CBKinase1_022849 CCN(CC(=O)Nc1ccccc1OC)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K12 compound treatment 2832879.0 -372000.0 -0.31 3255385.0 126000.0 0.1 -0.1507 -0.4578 3632736 CBKinase1_022850 COC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)sc(C)c1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K13 compound treatment 3255789.0 51200.0 0.04 3261981.0 133000.0 0.11 0.1052 0.9221 3632737 CBKinase1_022851 Cc1ccc(cc1)S(=O)(=O)N(Cc2cc3cccc(C)c3nc2O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K14 compound treatment 3534864.0 330000.0 0.28 3496525.0 367000.0 0.29 0.4039 0.9997 3632738 CBKinase1_022852 Cc1cc(C)c(C)c(Oc2coc3cc(OCC(=O)Nc4ccccc4F)ccc3c2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K15 mock treatment 3690128.0 486000.0 0.41 3324875.0 195000.0 0.16 0.3997 0.9123 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K16 mock treatment 3324037.0 119000.0 0.1 2902262.0 -227000.0 -0.18 -0.0568 -0.2741 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K17 compound treatment 2948478.0 -256000.0 -0.22 3017952.0 -111000.0 -0.09 -0.2156 -0.9229 3632739 CBKinase1_022853 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K18 compound treatment 2702789.0 -502000.0 -0.42 2780881.0 -349000.0 -0.28 -0.4957 -0.9792 3632740 CBKinase1_022854 Brc1ccc(NC(=O)NCCCN2CCCC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K19 compound treatment 3657734.0 453000.0 0.38 2849825.0 -280000.0 -0.22 0.1127 0.2547 3632741 CBKinase1_022855 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K20 compound treatment 3240328.0 35700.0 0.03 2881009.0 -248000.0 -0.2 -0.1187 -0.5926 3632742 CBKinase1_022856 COc1ccccc1NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K21 compound treatment 2778665.0 -426000.0 -0.36 2697342.0 -432000.0 -0.34 -0.4976 -0.9998 3632743 CBKinase1_022857 Oc1ccccc1c2nnc(SCC(=O)NC3CCCCC3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K22 compound treatment 2603651.0 -601000.0 -0.51 2093651.0 -1040000.0 -0.83 -0.9422 -0.9726 1268263 CBKinase1_022858 Fc1ccc(cc1)C(=O)Oc2c(CN3CCOCC3)cc(Cl)c4cccnc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K23 mock treatment 2868988.0 -336000.0 -0.28 3399092.0 270000.0 0.21 -0.0482 -0.1356 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 K24 mock treatment 2258337.0 -946000.0 -0.8 2580919.0 -549000.0 -0.44 -0.8735 -0.9599 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L01 compound treatment 2672290.0 -532000.0 -0.45 2579871.0 -550000.0 -0.44 -0.6272 -0.9999 3632744 CBKinase1_022859 CSc1ccc(cc1)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L02 compound treatment 3091575.0 -113000.0 -0.1 2938348.0 -191000.0 -0.15 -0.1751 -0.9745 3632745 CBKinase1_022860 Cc1cc(C)c(NC(=O)CSc2nc(C)cc(O)n2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L03 compound treatment 3038006.0 -167000.0 -0.14 2970856.0 -159000.0 -0.13 -0.1887 -0.9986 3632746 CBKinase1_022861 CCCN1C(=O)C(O)(CC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])c3cc(Br)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L04 compound treatment 3344584.0 140000.0 0.12 2915336.0 -214000.0 -0.17 -0.0372 -0.1791 3632747 CBKinase1_022862 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccccc3F)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L05 compound treatment 3261347.0 56800.0 0.05 3547297.0 418000.0 0.33 0.2693 0.8005 3632748 CBKinase1_022863 OC(=O)C1CCCCC1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L06 compound treatment 3904918.0 700000.0 0.59 3189708.0 60300.0 0.05 0.4517 0.7621 3632749 CBKinase1_022864 NC(=O)COc1ccc(NC(=O)c2cc(ccc2Cl)n3cnnc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L07 mock treatment 3978195.0 774000.0 0.65 3632655.0 503000.0 0.4 0.745 0.9727 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L08 mock treatment 4042275.0 838000.0 0.71 3698141.0 569000.0 0.45 0.8201 0.977 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L09 compound treatment 3989907.0 785000.0 0.66 3750299.0 621000.0 0.49 0.8183 0.9897 3632750 CBKinase1_022865 CCOc1ccccc1NC(=O)CSc2nc(N)n[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L10 compound treatment 3844772.0 640000.0 0.54 3844848.0 715000.0 0.57 0.785 0.9996 1785222 CBKinase1_022866 Cc1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)[nH]2)cc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L11 compound treatment 3515300.0 311000.0 0.26 4074582.0 945000.0 0.75 0.718 0.9002 3632751 CBKinase1_022867 CCN(CC(=O)Nc1cccc(SC)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L12 compound treatment 4081130.0 877000.0 0.74 3666224.0 537000.0 0.43 0.8253 0.9662 3632752 CBKinase1_022868 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L13 compound treatment 4076523.0 872000.0 0.74 3567873.0 438000.0 0.35 0.7671 0.9421 1500682 CBKinase1_022869 Cc1sc2ncn(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L14 compound treatment 3804245.0 600000.0 0.51 4401966.0 1270000.0 1.01 1.0748 0.9484 3632753 CBKinase1_022870 Cc1ccc(NC(=O)COc2ccc3cc(c4ccc(Cl)cc4)c(=O)oc3c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L15 mock treatment 4134512.0 930000.0 0.78 4062965.0 934000.0 0.74 1.0808 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L16 mock treatment 4491623.0 1290000.0 1.09 4109848.0 980000.0 0.78 1.3202 0.987 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L17 compound treatment 4330054.0 1130000.0 0.95 3949283.0 820000.0 0.65 1.1333 0.9834 1968076 CBKinase1_022871 COc1ccc(C)cc1S(=O)(=O)NCCO 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L18 compound treatment 4280172.0 1080000.0 0.91 3009661.0 -120000.0 -0.1 0.574 0.6292 3632754 CBKinase1_022872 CC(=O)N1CCN(Cc2nc3cc(NC(=O)Cn4nc(C)c5ccccc5c4=O)ccc3n2C)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L19 compound treatment 4073396.0 869000.0 0.73 4031081.0 902000.0 0.72 1.0263 1.0 3632755 CBKinase1_022873 CC(=O)Nc1ccc(Br)cc1c2nc3ccccc3nc2OCc4cccc(Cl)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L20 compound treatment 4104012.0 899000.0 0.76 3786548.0 657000.0 0.52 0.9068 0.9836 3632756 CBKinase1_022874 Cc1ccc2n(C)c3nc(SCCN4CCOCC4)nnc3c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L21 compound treatment 3670593.0 466000.0 0.39 3242304.0 113000.0 0.09 0.3415 0.847 1706732 CBKinase1_022875 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2sc3CCCCc3c2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L22 compound treatment 3896934.0 692000.0 0.58 3786920.0 657000.0 0.52 0.7835 0.9985 3632757 CBKinase1_022876 CC(=O)c1ccccc1OCC(O)CNC2CCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L23 mock treatment 3635570.0 431000.0 0.36 3757074.0 628000.0 0.5 0.6108 0.9877 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 L24 mock treatment 3020789.0 -184000.0 -0.16 2951393.0 -178000.0 -0.14 -0.21 -0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M01 compound treatment 2095443.0 -1110000.0 -0.94 2456433.0 -673000.0 -0.54 -1.0409 -0.9651 3632758 CBKinase1_022877 COc1cccc2cc(oc12)c3nnc(SCC(=O)N4c5ccccc5Sc6ccccc46)n3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M02 compound treatment 2338794.0 -866000.0 -0.73 2432562.0 -697000.0 -0.56 -0.9092 -0.9909 3632759 CBKinase1_022878 Cc1ccc(C)c(NC(=O)c2ccc(OCC(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M03 compound treatment 2633662.0 -571000.0 -0.48 2694588.0 -435000.0 -0.35 -0.5856 -0.987 3632760 CBKinase1_022879 COc1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M04 compound treatment 3088267.0 -116000.0 -0.1 2904807.0 -225000.0 -0.18 -0.196 -0.9599 3632761 CBKinase1_022880 Ic1cccc(NC(=O)CSc2nccc(=O)[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M05 compound treatment 2968615.0 -236000.0 -0.2 3622444.0 493000.0 0.39 0.1371 0.3113 3632762 CBKinase1_022881 CN(C)c1nc(N)nc(CSc2nnnn2C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M06 compound treatment 2980824.0 -224000.0 -0.19 2718243.0 -411000.0 -0.33 -0.3652 -0.9656 3632763 CBKinase1_022882 COc1ccc(C)cc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M07 compound treatment 3221227.0 16600.0 0.01 3169258.0 39800.0 0.03 0.0324 0.9327 3632764 CBKinase1_022883 COc1ccc(NC(=O)CNC(=O)c2ccc(cc2)C(C)(C)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M08 compound treatment 3061150.0 -143000.0 -0.12 3660137.0 531000.0 0.42 0.2135 0.4854 1384250 CBKinase1_022884 COc1ccccc1CN2CC(CC2=O)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M09 mock treatment 3556938.0 352000.0 0.3 3113346.0 -16100.0 -0.01 0.2011 0.6759 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M10 mock treatment 3566159.0 362000.0 0.3 3061062.0 -68400.0 -0.05 0.1771 0.5717 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M11 compound treatment 3489545.0 285000.0 0.24 3582038.0 453000.0 0.36 0.425 0.9805 3632765 CBKinase1_022885 CCn1c(SCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)nnc1c3cc(Br)ccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M12 compound treatment 3716648.0 512000.0 0.43 3261698.0 132000.0 0.11 0.3799 0.8546 3632766 CBKinase1_022886 FC(F)(F)c1cccc(NC(=O)CSc2nc3cc4ccccc4cc3[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M13 mock treatment 2724810.0 -480000.0 -0.4 3560792.0 431000.0 0.34 -0.0431 -0.0811 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M14 mock treatment 3373021.0 168000.0 0.14 3581824.0 452000.0 0.36 0.3554 0.9171 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M15 compound treatment 3655300.0 451000.0 0.38 3404684.0 275000.0 0.22 0.4239 0.9659 3632767 CBKinase1_022887 COc1cc(NC(=O)CSc2nc(C)cc(C)n2)cc(OC)c1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M16 compound treatment 3565721.0 361000.0 0.3 3277849.0 148000.0 0.12 0.299 0.9151 3632768 CBKinase1_022888 COc1ccc(NC(=O)COc2ccc(CO)cc2OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M17 compound treatment 4533853.0 1330000.0 1.12 4079455.0 950000.0 0.76 1.3282 0.9817 3632769 CBKinase1_022889 CCOc1c(Cl)c(Cl)ccc1S(=O)(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M18 compound treatment 3758065.0 553000.0 0.47 3372617.0 243000.0 0.19 0.4672 0.9242 3632770 CBKinase1_022890 CC(NS(=O)(=O)c1cc(Cl)ccc1Cl)C(=O)Nc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M19 compound treatment 3302315.0 97700.0 0.08 3404566.0 275000.0 0.22 0.2133 0.9107 3632771 CBKinase1_022891 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccccc2Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M20 compound treatment 3359500.0 155000.0 0.13 3776499.0 647000.0 0.52 0.4571 0.8591 3632772 CBKinase1_022892 COc1ccc(OC)c(NC(=O)CNC(=O)c2ccc(cc2)C(C)(C)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M21 compound treatment 3349285.0 145000.0 0.12 2732252.0 -397000.0 -0.32 -0.1376 -0.4054 3632773 CBKinase1_022893 Cn1c(SCC(=O)Nc2ccnc3ccccc23)nnc1c4ccncc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M22 compound treatment 3161382.0 -43200.0 -0.04 2933289.0 -196000.0 -0.16 -0.1363 -0.8492 3632774 CBKinase1_022894 Cc1cc(Cn2ccc(n2)C(F)(F)F)c(C)c(c1)c3c(C#N)c(N)nc4CCCCc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M23 compound treatment 2769284.0 -435000.0 -0.37 2600060.0 -529000.0 -0.42 -0.558 -0.9976 1351131 CBKinase1_022895 CN(c1ccc(OCC(=O)O)cc1)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 M24 compound treatment 2376927.0 -828000.0 -0.7 2530789.0 -599000.0 -0.48 -0.8311 -0.9828 3632775 CBKinase1_022896 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccccc2SC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N01 compound treatment 2555119.0 -649000.0 -0.55 2829630.0 -300000.0 -0.24 -0.5564 -0.9308 3632776 CBKinase1_022897 CC1=CCC(C(C1)C(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N02 compound treatment 2590596.0 -614000.0 -0.52 2880613.0 -249000.0 -0.2 -0.5065 -0.9132 3632777 CBKinase1_022898 CCOc1ccc(C)cc1S(=O)(=O)n2cnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N03 compound treatment 2539967.0 -665000.0 -0.56 3043288.0 -86200.0 -0.07 -0.445 -0.7878 3632778 CBKinase1_022899 CCn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N04 compound treatment 3209865.0 5270.0 0.0 3761436.0 632000.0 0.5 0.3593 0.7133 3632779 CBKinase1_022900 CC(C)n1c(SCCC(=O)O)nc2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N05 compound treatment 3203542.0 -1050.0 0.0 3613409.0 484000.0 0.39 0.2721 0.7055 3632780 CBKinase1_022901 COC(=O)c1sccc1NC(=O)COc2cccc(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N06 compound treatment 2935113.0 -269000.0 -0.23 3487876.0 358000.0 0.29 0.0413 0.1131 3632781 CBKinase1_022902 COC(=O)Cc1c(C)[nH]c2nc(NCc3cccs3)nn2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N07 compound treatment 3316176.0 112000.0 0.09 3752295.0 623000.0 0.5 0.4176 0.8264 3632782 CBKinase1_022903 CCCN(Cc1cc2cccc(C)c2nc1O)C(=O)c3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N08 compound treatment 3741076.0 536000.0 0.45 3883739.0 754000.0 0.6 0.7451 0.9902 3632783 CBKinase1_022904 Cc1nn(CC(=O)Nc2ccc3n4CCN(Cc4nc3c2)C5CCCCC5)c(=O)c6ccccc16 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N09 mock treatment 3771643.0 567000.0 0.48 3881947.0 752000.0 0.6 0.7623 0.9937 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N10 mock treatment 3862764.0 658000.0 0.56 3700421.0 571000.0 0.46 0.7144 0.9951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N11 compound treatment 3683830.0 479000.0 0.4 4047929.0 918000.0 0.73 0.8035 0.9608 3632784 CBKinase1_022905 Cc1coc(C)c1C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N12 compound treatment 3795644.0 591000.0 0.5 3548552.0 419000.0 0.33 0.5887 0.981 3632785 CBKinase1_022906 CCC(=O)N1CCN(CC1)c2ccc(Cl)cc2NC(=O)COc3ccc(cc3)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N13 mock treatment 4028107.0 824000.0 0.69 3744051.0 615000.0 0.49 0.8376 0.9854 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N14 mock treatment 3705739.0 501000.0 0.42 3712230.0 583000.0 0.46 0.6274 0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N15 compound treatment 3816326.0 612000.0 0.52 3744404.0 615000.0 0.49 0.7114 0.9997 3632786 CBKinase1_022907 O=C(CC1N(CCNC1=O)C(=S)Nc2ccccc2)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N16 compound treatment 3994638.0 790000.0 0.67 2797910.0 -332000.0 -0.26 0.2844 0.3967 1306430 CBKinase1_022908 O=c1n(CCCn2ccnc2)c(=S)[nH]c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N17 compound treatment 3880298.0 676000.0 0.57 3331456.0 202000.0 0.16 0.5169 0.8727 3632787 CBKinase1_022909 COc1ccc(cc1)n2nnnc2SCC(=O)Nc3cc(C)c(Cl)cc3OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N18 compound treatment 3310900.0 106000.0 0.09 3991350.0 862000.0 0.69 0.5492 0.7927 3632788 CBKinase1_022910 CCOC(=O)c1ccc(NC(=O)CSc2nc3cc4ccccc4cc3[nH]2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N19 compound treatment 4071156.0 867000.0 0.73 4415287.0 1290000.0 1.02 1.2415 0.9863 3632789 CBKinase1_022911 CCn1c(SCC(=O)c2ccccc2)nnc1c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N20 compound treatment 4110716.0 906000.0 0.76 3468132.0 339000.0 0.27 0.7313 0.9022 3632790 CBKinase1_022912 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cc(C)ccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N21 compound treatment 3611912.0 407000.0 0.34 2916798.0 -213000.0 -0.17 0.1231 0.3213 3632791 CBKinase1_022913 Cc1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N22 compound treatment 2878473.0 -326000.0 -0.28 3085364.0 -44100.0 -0.04 -0.2194 -0.791 3632792 CBKinase1_022914 CSc1nc2sc3CCCc3c2c4nnc(SCC(=O)Nc5ccccc5)n14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N23 compound treatment 2521954.0 -683000.0 -0.58 3034731.0 -94700.0 -0.08 -0.4605 -0.793 3632793 CBKinase1_022915 COc1ccc(C)cc1S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 N24 compound treatment 2424313.0 -780000.0 -0.66 2407231.0 -722000.0 -0.58 -0.8724 -0.9978 3632794 CBKinase1_022916 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(C)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O01 compound treatment 3558946.0 354000.0 0.3 2550771.0 -579000.0 -0.46 -0.1148 -0.2089 3123517 CBKinase1_022917 CN(Cc1cc2cc(C)ccc2nc1O)C(=O)c3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O02 compound treatment 3567384.0 363000.0 0.31 3719957.0 591000.0 0.47 0.5492 0.9783 3632795 CBKinase1_022918 FC(F)(F)C1(N=C(Nc2c1c(=O)[nH]c(=O)n2Cc3ccco3)C4CCCCC4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O03 compound treatment 3289633.0 85000.0 0.07 2846745.0 -283000.0 -0.23 -0.1086 -0.4593 3632796 CBKinase1_022919 COC(=O)c1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c3cc(C)ccc3OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O04 compound treatment 3935689.0 731000.0 0.62 3378184.0 249000.0 0.2 0.5762 0.8896 3632797 CBKinase1_022920 CCN(CC(=O)Nc1cccc(c1)C(=O)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O05 compound treatment 2716517.0 -488000.0 -0.41 3282756.0 153000.0 0.12 -0.2047 -0.4767 3632798 CBKinase1_022921 NC(=O)c1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Br)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O06 compound treatment 4249940.0 1050000.0 0.88 3131458.0 2010.0 0.0 0.6246 0.7084 3632799 CBKinase1_022922 CCOC(=O)c1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O07 compound treatment 4361536.0 1160000.0 0.98 3366216.0 237000.0 0.19 0.8235 0.8285 3040369 CBKinase1_022923 CN(Cc1nc2ccccc2n1C)C(=O)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O08 compound treatment 3402003.0 197000.0 0.17 3649119.0 520000.0 0.41 0.4106 0.9198 3632800 CBKinase1_022924 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(I)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O09 compound treatment 3319998.0 115000.0 0.1 3399090.0 270000.0 0.21 0.2208 0.9359 3632801 CBKinase1_022925 COc1ccccc1CNS(=O)(=O)c2cc(C)ccc2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O10 compound treatment 3260820.0 56200.0 0.05 2956523.0 -173000.0 -0.14 -0.0639 -0.4386 3632802 CBKinase1_022926 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O11 mock treatment 3501921.0 297000.0 0.25 2765257.0 -364000.0 -0.29 -0.0279 -0.0728 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O12 mock treatment 3574605.0 370000.0 0.31 3918232.0 789000.0 0.63 0.6652 0.9478 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O13 compound treatment 4016068.0 811000.0 0.68 4007510.0 878000.0 0.7 0.9789 0.9999 3632803 CBKinase1_022927 CN(Cc1cc2cc(C)ccc2nc1O)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O14 compound treatment 4194128.0 990000.0 0.83 4255153.0 1130000.0 0.9 1.2246 0.9993 3632804 CBKinase1_022928 COc1ccccc1NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O15 compound treatment 4288202.0 1080000.0 0.91 4202278.0 1070000.0 0.86 1.251 0.9994 3632805 CBKinase1_022929 CC(=O)Nc1ccc(OCC(O)CNC2CCCC2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O16 compound treatment 4306129.0 1100000.0 0.93 4150119.0 1020000.0 0.81 1.2322 0.9978 3632806 CBKinase1_022930 COc1ccc(NC(=O)Cn2cnc3sc4CC(C)CCc4c3c2=O)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O17 compound treatment 4523620.0 1320000.0 1.11 4383831.0 1250000.0 1.0 1.4937 0.9986 3632807 CBKinase1_022931 Cc1cc(C)nc(Nc2n[nH]c(COc3cccc4cccnc34)n2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O18 compound treatment 4036207.0 832000.0 0.7 3992799.0 863000.0 0.69 0.9826 1.0 3632808 CBKinase1_022932 COc1cccc(c1)C(=O)OCc2nc3ccccc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O19 compound treatment 4083661.0 879000.0 0.74 3845183.0 716000.0 0.57 0.9277 0.9916 3632809 CBKinase1_022933 COc1ccc(cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O20 compound treatment 4066644.0 862000.0 0.73 3589685.0 460000.0 0.37 0.7736 0.9498 3632810 CBKinase1_022934 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3ccc(F)cc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O21 compound treatment 3655982.0 451000.0 0.38 3713698.0 584000.0 0.47 0.5985 0.995 3632811 CBKinase1_022935 COC(=O)c1ccccc1NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O22 compound treatment 3575281.0 371000.0 0.31 3287021.0 158000.0 0.13 0.3099 0.9197 3632812 CBKinase1_022936 COc1cccc(NC(=O)CC2N(C3CCCCC3NC2=O)C(=O)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O23 compound treatment 3229514.0 24900.0 0.02 3355401.0 226000.0 0.18 0.1422 0.7843 3632813 CBKinase1_022937 NC(=O)CN1C(=O)C(O)(CC(=O)c2cccnc2)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 O24 compound treatment 2685277.0 -519000.0 -0.44 2917589.0 -212000.0 -0.17 -0.4291 -0.9141 3632814 CBKinase1_022938 COc1ccc(cc1OC)c2c(oc3cc(OCC(=O)Nc4ccc(C)cc4)ccc3c2=O)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P01 compound treatment 2967332.0 -237000.0 -0.2 2184744.0 -945000.0 -0.75 -0.6739 -0.865 3632815 CBKinase1_022939 Cc1cc(nc(SCC(=O)c2cccc(c2)[N+](=O)[O-])n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P02 compound treatment 2121250.0 -1080000.0 -0.91 2482038.0 -647000.0 -0.52 -1.011 -0.9634 3632816 CBKinase1_022940 Cc1ccc(cc1)c2nc(SCC(=O)Nc3cccc(c3)C(F)(F)F)c4COC(C)(C)Cc4n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P03 compound treatment 3282094.0 77500.0 0.07 2904609.0 -225000.0 -0.18 -0.0805 -0.422 1342991 CBKinase1_022941 O=C(CSc1nnc(Cc2ccccc2)o1)N3c4ccccc4Sc5ccccc35 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P04 compound treatment 2989035.0 -216000.0 -0.18 2431120.0 -698000.0 -0.56 -0.5221 -0.8917 3632817 CBKinase1_022942 Clc1ccc(cc1C(=O)NCCN2CCOCC2)n3cnnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P05 compound treatment 2692596.0 -512000.0 -0.43 2824723.0 -305000.0 -0.24 -0.4771 -0.9629 3632818 CBKinase1_022943 Clc1ccc(NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P06 compound treatment 3236839.0 32200.0 0.03 2835233.0 -294000.0 -0.23 -0.1466 -0.6209 3632819 CBKinase1_022944 COc1cccc(CNc2nc3[nH]c(C)c(Cc4ccccc4)c(=O)n3n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P07 compound treatment 3166218.0 -38400.0 -0.03 3128824.0 -626.0 0.0 -0.0232 -0.7179 3632820 CBKinase1_022945 Clc1ccc(cc1)C(=O)Nc2ccc(OCc3nc4ccccc4s3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P08 compound treatment 3208200.0 3610.0 0.0 3270496.0 141000.0 0.11 0.0816 0.726 3632821 CBKinase1_022946 Clc1ccccc1NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P09 compound treatment 3267858.0 63300.0 0.05 3490835.0 361000.0 0.29 0.2414 0.8241 3632822 CBKinase1_022947 Clc1ccc(cc1C(=O)Nc2cccc(c2)S(=O)(=O)N3CCCC3)n4cnnc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P10 compound treatment 2659633.0 -545000.0 -0.46 2674751.0 -455000.0 -0.36 -0.5813 -0.9931 3632823 CBKinase1_022948 CCOc1ccc(Oc2nc(nc(n2)N3CCOCC3)N(CC)CC)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P11 mock treatment 3266487.0 61900.0 0.05 3342715.0 213000.0 0.17 0.1571 0.8836 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P12 mock treatment 3245003.0 40400.0 0.03 3283830.0 154000.0 0.12 0.1111 0.8702 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P13 compound treatment 3504996.0 300000.0 0.25 5866797.0 2740000.0 2.18 1.7219 0.784 3632824 CBKinase1_022949 CCOC(=O)c1ccc(NC(=O)CCC2COc3ccccc3O2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P14 compound treatment 3229524.0 24900.0 0.02 3499456.0 370000.0 0.29 0.2234 0.7556 1559071 CBKinase1_022950 Cc1cc(Cl)ccc1NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P15 compound treatment 3628422.0 424000.0 0.36 3673994.0 545000.0 0.43 0.5597 0.9954 3632825 CBKinase1_022951 COC(=O)C(CC(=O)Nc1cc(Cl)cc(Cl)c1)N2CCc3ccccc3C2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P16 compound treatment 3497236.0 293000.0 0.25 3942801.0 813000.0 0.65 0.6329 0.9124 3632826 CBKinase1_022952 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccc(Br)cc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P17 compound treatment 3357138.0 153000.0 0.13 3275760.0 146000.0 0.12 0.1734 0.9988 3632827 CBKinase1_022953 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(F)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P18 compound treatment 3582576.0 378000.0 0.32 3398033.0 269000.0 0.21 0.3768 0.9812 3632828 CBKinase1_022954 CCOC(=O)c1c[nH]c2nc(NCc3ccc(OC)c(OC)c3)nn2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P19 compound treatment 2932099.0 -272000.0 -0.23 3106970.0 -22500.0 -0.02 -0.1752 -0.7599 3632829 CBKinase1_022955 Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)c4cccc(F)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P20 compound treatment 3176111.0 -28500.0 -0.02 3218038.0 88600.0 0.07 0.0329 0.4417 3632830 CBKinase1_022956 CCc1ccc(o1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P21 compound treatment 3484028.0 279000.0 0.24 3772278.0 643000.0 0.51 0.529 0.9379 3632831 CBKinase1_022957 Cn1nnnc1SCC(=O)Nc2ccc(I)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P22 compound treatment 3629293.0 425000.0 0.36 3092983.0 -36500.0 -0.03 0.2328 0.6476 3632832 CBKinase1_022958 COC(=O)c1c(NC(=O)c2ccc(NS(=O)(=O)C)cc2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P23 compound treatment 3067100.0 -137000.0 -0.12 3057991.0 -71500.0 -0.06 -0.1223 -0.9464 3632833 CBKinase1_022959 COc1ccc(NC(=O)C(C)NS(=O)(=O)c2ccc(F)cc2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2395 P24 compound treatment 2788177.0 -416000.0 -0.35 2573622.0 -556000.0 -0.44 -0.5616 -0.9934 3632834 CBKinase1_022960 COc1ccc(cc1)C(=O)N2CCNC(=O)C2CC(=O)Nc3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A01 compound treatment 3321066.0 141000.0 0.12 2476163.0 -483000.0 -0.39 -0.1884 -0.4672 3632835 CBKinase1_022961 Cc1nn(c(CC(C)(C)C(=O)O)c1C(=O)O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A02 compound treatment 2469051.0 -711000.0 -0.6 2938938.0 -20700.0 -0.02 -0.4358 -0.7262 3632836 CBKinase1_022962 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3sc4CCCCc4c3C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A03 compound treatment 3082018.0 -98100.0 -0.08 3169389.0 210000.0 0.17 0.0597 0.3201 3632837 CBKinase1_022963 Cn1cccc1CNCCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A04 compound treatment 2587816.0 -592000.0 -0.5 2706129.0 -253000.0 -0.2 -0.4961 -0.9206 3632838 CBKinase1_022964 COC(=O)c1ccccc1NC(=O)Cn2c(SC)c(F)cnc2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A05 compound treatment 3085936.0 -94200.0 -0.08 3468213.0 509000.0 0.41 0.2305 0.5579 1417144 CBKinase1_022965 Cc1ccc(NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(F)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A06 compound treatment 3291303.0 111000.0 0.09 3344601.0 385000.0 0.31 0.2833 0.8829 3632839 CBKinase1_022966 OC(=O)c1cccc(NCc2cccnc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A07 compound treatment 3761605.0 581000.0 0.49 3071014.0 111000.0 0.09 0.4096 0.8218 3632840 CBKinase1_022967 Cc1nn2c(CN(c3ccccc3)S(=O)(=O)c4ccccc4)nnc2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A08 compound treatment 3833201.0 653000.0 0.55 3276356.0 317000.0 0.25 0.568 0.9374 3632841 CBKinase1_022968 FC(F)(F)c1cccc(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A09 compound treatment 3595697.0 416000.0 0.35 3368105.0 409000.0 0.33 0.4781 0.9993 3632842 CBKinase1_022969 Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc4cccc(Cl)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A10 compound treatment 3869750.0 690000.0 0.58 3385950.0 426000.0 0.34 0.6516 0.9672 3632843 CBKinase1_022970 Cc1ncc([N+](=O)[O-])n1CC(=O)Nc2ccc(I)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A11 compound treatment 4153163.0 973000.0 0.82 3445549.0 486000.0 0.39 0.8542 0.9413 3632844 CBKinase1_022971 COc1ccccc1NC(=O)C2CC(=O)n3c(N2)nc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A12 compound treatment 3841310.0 661000.0 0.56 3388936.0 429000.0 0.34 0.6363 0.9725 3632845 CBKinase1_022972 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(Br)c(Cl)c3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A13 mock treatment 4377667.0 1200000.0 1.01 3446403.0 487000.0 0.39 0.9886 0.9136 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A14 mock treatment 4134665.0 955000.0 0.81 3169621.0 210000.0 0.17 0.6877 0.8362 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A15 compound treatment 3917844.0 738000.0 0.62 3290549.0 331000.0 0.26 0.6265 0.927 3632846 CBKinase1_022973 OC(=O)c1cccc(CSc2nnc([nH]2)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A16 compound treatment 4286369.0 1110000.0 0.93 3369288.0 410000.0 0.33 0.8907 0.901 3632847 CBKinase1_022974 [O-][N+](=O)c1cccc(c1)c2ccc(o2)C(=O)NC(=S)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A17 compound treatment 3974506.0 794000.0 0.67 3464396.0 505000.0 0.4 0.7583 0.9702 3632848 CBKinase1_022975 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(F)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A18 compound treatment 4107273.0 927000.0 0.78 3623116.0 664000.0 0.53 0.9269 0.9819 3632849 CBKinase1_022976 Cc1c(sc2ncn(CC(=O)Nc3ccccc3C(F)(F)F)c(=O)c12)C(=O)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A19 compound treatment 3866241.0 686000.0 0.58 3238183.0 279000.0 0.22 0.5662 0.9135 3632850 CBKinase1_022977 CC(NS(=O)(=O)c1cc(Cl)ccc1Cl)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A20 compound treatment 3960234.0 780000.0 0.66 3387742.0 428000.0 0.34 0.7066 0.9533 3632851 CBKinase1_022978 OC(=O)c1cccc(CSc2nnc(Cc3ccccc3)o2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A21 compound treatment 3648211.0 468000.0 0.39 3303854.0 344000.0 0.27 0.4732 0.9842 3037865 CBKinase1_022979 CC(=O)N(Cc1nnc2c3ccccc3c(C)nn12)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A22 compound treatment 3306483.0 126000.0 0.11 2828869.0 -131000.0 -0.1 0.0017 0.0113 3632852 CBKinase1_022980 CCN(CC(=O)Nc1ccccc1C(F)(F)F)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A23 compound treatment 3321363.0 141000.0 0.12 2706396.0 -253000.0 -0.2 -0.0585 -0.2495 3632853 CBKinase1_022981 Cc1ccc(cc1)S(=O)(=O)NCCNc2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 A24 compound treatment 3025425.0 -155000.0 -0.13 2516379.0 -443000.0 -0.35 -0.3421 -0.9083 3632854 CBKinase1_022982 CN(C(=O)Cn1c(C)ncc1[N+](=O)[O-])c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B01 compound treatment 2984107.0 -196000.0 -0.17 2703988.0 -256000.0 -0.2 -0.261 -0.9946 3632855 CBKinase1_022983 Cc1scc(C(=O)Nc2cccc(Cn3cccn3)c2)c1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B02 compound treatment 1229213.0 -1950000.0 -1.65 1171840.0 -1790000.0 -1.42 -2.1712 -0.9974 3632856 CBKinase1_022984 Cc1cccc(OCC(=O)Nc2ccc3n4CCN(Cc4nc3c2)C5CCCCC5)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B03 compound treatment 3299183.0 119000.0 0.1 2966683.0 7090.0 0.01 0.075 0.7457 3632857 CBKinase1_022985 CCCCc1ccc(cc1)c2csc(NC(=O)c3ccccc3[N+](=O)[O-])c2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B04 compound treatment 3497848.0 318000.0 0.27 3595769.0 636000.0 0.51 0.548 0.9556 1868345 CBKinase1_022986 Cc1cc(C)c2c(CC(=O)NCc3ccco3)coc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B05 compound treatment 3531735.0 352000.0 0.3 3736223.0 777000.0 0.62 0.6474 0.9432 3632858 CBKinase1_022987 Cc1nn(CCCNC(=O)C2CCCO2)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B06 compound treatment 3809062.0 629000.0 0.53 3648793.0 689000.0 0.55 0.7636 0.9998 3040364 CBKinase1_022988 Cc1nn2c(CN(C(=O)c3ccccc3)c4ccccc4)nnc2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B07 compound treatment 3883983.0 704000.0 0.59 3803780.0 844000.0 0.67 0.8956 0.9981 3632859 CBKinase1_022989 Cc1noc(C)c1C(=O)NCCCN2CCCC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B08 compound treatment 3955788.0 776000.0 0.65 4012572.0 1050000.0 0.84 1.0561 0.9924 3632860 CBKinase1_022990 CCOc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B09 compound treatment 4244528.0 1060000.0 0.9 3796353.0 837000.0 0.67 1.1064 0.9893 3632861 CBKinase1_022991 COc1ccc(OC)c(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B10 compound treatment 4010093.0 830000.0 0.7 3870510.0 911000.0 0.73 1.0084 0.9998 3632862 CBKinase1_022992 COc1ccc(cc1)C(=O)Nc2cccc(c2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B11 compound treatment 4052446.0 872000.0 0.74 3889629.0 930000.0 0.74 1.0445 1.0 3632863 CBKinase1_022993 Cc1ccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B12 compound treatment 4173434.0 993000.0 0.84 3680359.0 721000.0 0.57 0.9987 0.9831 3632864 CBKinase1_022994 O=C(CCC1COc2ccccc2O1)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B13 mock treatment 4496183.0 1320000.0 1.11 3805678.0 846000.0 0.67 1.2618 0.9715 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B14 mock treatment 4311371.0 1130000.0 0.95 4113149.0 1150000.0 0.92 1.3249 0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B15 compound treatment 3955720.0 776000.0 0.65 3921912.0 962000.0 0.77 1.005 0.9969 3632865 CBKinase1_022995 CCc1c(O)nc(SCC(=O)Nc2ccc(cc2)C(=O)C)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B16 compound treatment 4413123.0 1230000.0 1.04 3995636.0 1040000.0 0.83 1.3193 0.9935 3632866 CBKinase1_022996 COc1ccc(NC(=O)CNC(=O)c2ccc(OC)c(OC)c2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B17 compound treatment 4103584.0 923000.0 0.78 3898389.0 939000.0 0.75 1.0799 0.9998 3632867 CBKinase1_022997 Cc1nnc(SCc2nc(no2)c3ccc(C)cc3)n1c4cccc(C)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B18 compound treatment 4739064.0 1560000.0 1.31 4194846.0 1240000.0 0.98 1.626 0.9898 3632868 CBKinase1_022998 CCOc1c(CNCc2ccccn2)cccc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B19 compound treatment 4066646.0 887000.0 0.75 3954671.0 995000.0 0.79 1.0896 0.9996 3632869 CBKinase1_022999 O=C(CSc1nnc(c2ccco2)n1c3ccccc3)c4ccc5OCCOc5c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B20 compound treatment 4054202.0 874000.0 0.74 3766209.0 807000.0 0.64 0.9759 0.9977 3632870 CBKinase1_023000 COC(=O)CNC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(C)c(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B21 compound treatment 4091075.0 911000.0 0.77 3872101.0 913000.0 0.73 1.0576 0.9996 3632871 CBKinase1_023001 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cccc(c2)C(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B22 compound treatment 4363868.0 1180000.0 1.0 3833534.0 874000.0 0.7 1.1986 0.9845 3632872 CBKinase1_023002 Brc1ccccc1OCC(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B23 compound treatment 3764060.0 584000.0 0.49 3332787.0 373000.0 0.3 0.5586 0.9708 3632873 CBKinase1_023003 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCCCn3ccnc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 B24 compound treatment 3405865.0 226000.0 0.19 3180455.0 221000.0 0.18 0.2591 0.9992 3632874 CBKinase1_023004 CCOC(=O)CNC(=O)c1cc(C)on1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C01 compound treatment 2447280.0 -733000.0 -0.62 2473105.0 -486000.0 -0.39 -0.7113 -0.9748 3632875 CBKinase1_023005 CCc1nc(CNC(=O)c2cc(OC)c(OC)c(OC)c2)no1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C02 compound treatment 2456901.0 -723000.0 -0.61 2494172.0 -465000.0 -0.37 -0.6937 -0.9716 3632876 CBKinase1_023006 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2cccc(F)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C03 compound treatment 3054892.0 -125000.0 -0.11 2371389.0 -588000.0 -0.47 -0.4062 -0.8452 3632877 CBKinase1_023007 CCOc1ccc(Cl)cc1CNCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C04 compound treatment 2597440.0 -583000.0 -0.49 2478397.0 -481000.0 -0.38 -0.6187 -0.9925 3632878 CBKinase1_023008 Cc1cc(nc(SCC(=O)Nc2ccccc2)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C05 compound treatment 2868420.0 -312000.0 -0.26 2916220.0 -43400.0 -0.03 -0.2104 -0.7933 3632879 CBKinase1_023009 COc1ccc(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C06 compound treatment 2385700.0 -794000.0 -0.67 2483168.0 -476000.0 -0.38 -0.7423 -0.9638 3632880 CBKinase1_023010 COc1ccccc1NC(=O)c2ccc(OC(C)C(=O)Nc3cc(Cl)ccc3C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C07 compound treatment 2585414.0 -595000.0 -0.5 2587285.0 -372000.0 -0.3 -0.5645 -0.9686 3632881 CBKinase1_023011 CC(Oc1ccc(cc1)C(=O)Nc2ccc(C)cc2)C(=O)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C08 compound treatment 2776024.0 -404000.0 -0.34 2539018.0 -421000.0 -0.34 -0.4781 -1.0 3632882 CBKinase1_023012 COc1ccc(NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C09 compound treatment 2730804.0 -449000.0 -0.38 2742428.0 -217000.0 -0.17 -0.3904 -0.937 3632883 CBKinase1_023013 FC(F)(F)c1ccccc1NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C10 compound treatment 2822035.0 -358000.0 -0.3 2702940.0 -257000.0 -0.2 -0.3582 -0.982 3632884 CBKinase1_023014 CC(Oc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2)C(=O)Nc3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C11 mock treatment 2873812.0 -306000.0 -0.26 2696893.0 -263000.0 -0.21 -0.3308 -0.9946 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C12 mock treatment 3237108.0 57000.0 0.05 2568628.0 -391000.0 -0.31 -0.1864 -0.591 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C13 compound treatment 3104088.0 -76000.0 -0.06 2711063.0 -249000.0 -0.2 -0.1854 -0.8905 3632885 CBKinase1_023015 CCN(CC(=O)Nc1ccc(Br)cc1F)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C14 compound treatment 2976296.0 -204000.0 -0.17 2931945.0 -27600.0 -0.02 -0.1372 -0.7913 3632886 CBKinase1_023016 COC(=O)c1ccccc1NC(=O)CNC(=O)c2cccs2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C15 mock treatment 3150885.0 -29200.0 -0.02 2853050.0 -107000.0 -0.08 -0.0775 -0.8763 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C16 mock treatment 3080575.0 -99500.0 -0.08 2745682.0 -214000.0 -0.17 -0.1799 -0.9468 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C17 compound treatment 3154106.0 -26000.0 -0.02 2885444.0 -74100.0 -0.06 -0.0573 -0.909 3632887 CBKinase1_023017 CCOc1ccc(cc1)N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C18 compound treatment 3132420.0 -47700.0 -0.04 2877307.0 -82300.0 -0.07 -0.0748 -0.9725 3632888 CBKinase1_023018 Cc1cc(O)nc(SCC(=O)Nc2ccc(I)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C19 compound treatment 2918290.0 -262000.0 -0.22 2752366.0 -207000.0 -0.17 -0.273 -0.9898 3632889 CBKinase1_023019 COC(=O)c1c(NC(=O)NS(=O)(=O)c2ccc(C)cc2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C20 compound treatment 3021198.0 -159000.0 -0.13 2511812.0 -448000.0 -0.36 -0.3472 -0.9106 3632890 CBKinase1_023020 O=C(Nc1ccc(Oc2ccccc2)cc1)C3CC(=O)n4ncnc4N3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C21 compound treatment 2638601.0 -542000.0 -0.46 2742700.0 -217000.0 -0.17 -0.4452 -0.9116 3632891 CBKinase1_023021 CN(c1cccc(NC(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)c1)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C22 compound treatment 2836397.0 -344000.0 -0.29 2746598.0 -213000.0 -0.17 -0.3251 -0.9675 3632892 CBKinase1_023022 Cc1cc(I)ccc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C23 compound treatment 3026040.0 -154000.0 -0.13 2434679.0 -525000.0 -0.42 -0.3877 -0.885 3632893 CBKinase1_023023 COc1ccc(OC)c(c1)C2N=C(Nc3nc4ccccc4s3)NC5=C2C(=O)CC(C)(C)C5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 C24 compound treatment 2559075.0 -621000.0 -0.52 2290885.0 -669000.0 -0.53 -0.7473 -1.0 3632894 CBKinase1_023024 [O-][N+](=O)c1cccc(NC(=O)CN2C(=O)C3CCC(CC3C2=O)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D01 compound treatment 2458295.0 -722000.0 -0.61 2736701.0 -223000.0 -0.18 -0.5562 -0.8769 3632895 CBKinase1_023025 COC(=O)c1cc(sc1NC(=O)c2cnccn2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D02 compound treatment 2450378.0 -730000.0 -0.62 2979126.0 19500.0 0.02 -0.4242 -0.689 3632896 CBKinase1_023026 CC(Oc1ccc(cc1)C(=O)Nc2cccc(C)c2C)C(=O)Nc3ccccc3C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D03 compound treatment 2499367.0 -681000.0 -0.57 3217416.0 258000.0 0.21 -0.2607 -0.4275 3632897 CBKinase1_023027 COc1ccccc1NC(=O)c2c(NC(=O)c3cccnc3)sc4CC(C)CCc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D04 compound treatment 2917582.0 -263000.0 -0.22 3097309.0 138000.0 0.11 -0.079 -0.3195 3632898 CBKinase1_023028 Cc1ccc(Oc2ccc(NC(=O)CN3C(=O)C4C(C5C=CC4C6CC65)C3=O)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D05 compound treatment 3356776.0 177000.0 0.15 3196654.0 237000.0 0.19 0.239 0.9931 3632899 CBKinase1_023029 Cc1scc(C(=O)NCCc2ccc(cc2)S(=O)(=O)N)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D06 compound treatment 2982705.0 -197000.0 -0.17 3155251.0 196000.0 0.16 -0.0075 -0.0328 3632900 CBKinase1_023030 Cc1nnc(SCc2ccc(CSc3nnc(C)c(=O)[nH]3)cc2)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D07 compound treatment 3501172.0 321000.0 0.27 3496459.0 537000.0 0.43 0.4941 0.9756 3632901 CBKinase1_023031 Clc1cc(Cl)cc(NC(=O)CC2Nc3ccccc3NC2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D08 compound treatment 3338508.0 158000.0 0.13 3231222.0 272000.0 0.22 0.2476 0.9731 3632902 CBKinase1_023032 Fc1ccccc1NC(=O)CSc2nc(=O)c3c4CCCCc4sc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D09 compound treatment 3386445.0 206000.0 0.17 3113933.0 154000.0 0.12 0.21 0.9856 3632903 CBKinase1_023033 COC(=O)c1cccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D10 compound treatment 3161967.0 -18200.0 -0.02 3006053.0 46500.0 0.04 0.0154 0.3832 3632904 CBKinase1_023034 COc1ccc(NC(=O)CSc2nc3scc(C)c3c(=O)[nH]2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D11 mock treatment 3286423.0 106000.0 0.09 3231164.0 272000.0 0.22 0.2165 0.9239 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D12 mock treatment 3289600.0 109000.0 0.09 3346472.0 387000.0 0.31 0.2833 0.8802 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D13 compound treatment 3599003.0 419000.0 0.35 3315936.0 356000.0 0.28 0.4507 0.9941 3632905 CBKinase1_023035 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1F)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D14 compound treatment 3268936.0 88800.0 0.07 3264631.0 305000.0 0.24 0.2249 0.884 3632906 CBKinase1_023036 COc1cccc(NC(=O)CNC(=O)c2ccc(cc2)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D15 mock treatment 3440860.0 261000.0 0.22 3442513.0 483000.0 0.38 0.4277 0.9648 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D16 mock treatment 3480903.0 301000.0 0.25 3173644.0 214000.0 0.17 0.3 0.9814 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D17 compound treatment 3533366.0 353000.0 0.3 3148920.0 189000.0 0.15 0.3174 0.9503 1984866 CBKinase1_023037 Cc1ncsc1CCSc2n[nH]c(=O)n2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D18 compound treatment 3223786.0 43700.0 0.04 3255705.0 296000.0 0.24 0.1929 0.8077 3632907 CBKinase1_023038 FC(F)(F)c1nc(SCC(=O)Nc2cccc(Cl)c2Cl)nc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D19 compound treatment 3242436.0 62300.0 0.05 3095216.0 136000.0 0.11 0.1136 0.9451 3632908 CBKinase1_023039 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D20 compound treatment 3432268.0 252000.0 0.21 3293037.0 333000.0 0.27 0.3383 0.9939 3632909 CBKinase1_023040 CCOC(=O)c1sc(NC(=O)c2cnccn2)c(C(=O)OC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D21 compound treatment 3023777.0 -156000.0 -0.13 2866088.0 -93500.0 -0.07 -0.146 -0.9635 3027815 CBKinase1_023041 CCCn1cnc2cc(NCc3ccccc3O)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D22 compound treatment 3215474.0 35300.0 0.03 2983227.0 23600.0 0.02 0.0344 0.9755 3632910 CBKinase1_023042 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2c(C)noc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D23 compound treatment 2814537.0 -366000.0 -0.31 2736347.0 -223000.0 -0.18 -0.3439 -0.9659 3632911 CBKinase1_023043 Cc1ccc(NS(=O)(=O)c2cc(ccc2Cl)C(=O)NCC3CCCO3)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 D24 compound treatment 2836406.0 -344000.0 -0.29 2173908.0 -786000.0 -0.63 -0.6478 -0.9388 3632912 CBKinase1_023044 Cc1sc(NC(=O)c2ccccc2)c(C(=O)NCc3cccnc3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E01 mock treatment 1307700.0 -1870000.0 -1.58 1181050.0 -1780000.0 -1.42 -2.1192 -0.9985 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E02 mock treatment 1557796.0 -1620000.0 -1.37 1617437.0 -1340000.0 -1.07 -1.7241 -0.9926 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E03 compound treatment 1598587.0 -1580000.0 -1.33 1579356.0 -1380000.0 -1.1 -1.7212 -0.9954 3632913 CBKinase1_023045 OC(CNC1CCCC1)COc2ccccc2[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E04 compound treatment 1642259.0 -1540000.0 -1.3 1717708.0 -1240000.0 -0.99 -1.6172 -0.9911 3038609 CBKinase1_023046 Oc1nc2ccccc2cc1CN(C3CCCCC3)C(=O)c4cccc(Cl)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E05 compound treatment 1760542.0 -1420000.0 -1.2 1708627.0 -1250000.0 -1.0 -1.5517 -0.9959 3632914 CBKinase1_023047 Cc1ccc(NC(=O)CNC(=O)c2ccc(cc2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E06 compound treatment 1733629.0 -1450000.0 -1.22 1738116.0 -1220000.0 -0.97 -1.5512 -0.9937 3632915 CBKinase1_023048 CC(=O)Nc1ccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E07 compound treatment 2525658.0 -654000.0 -0.55 1933183.0 -1030000.0 -0.82 -0.9688 -0.9817 3632916 CBKinase1_023049 COc1ccc(OC)c(NC(=O)C2CC(=O)n3ncnc3N2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E08 compound treatment 2161499.0 -1020000.0 -0.86 2148952.0 -811000.0 -0.65 -1.0644 -0.9901 3632917 CBKinase1_023050 CCOc1ccccc1NC(=O)CSc2nc(N)cc(O)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E09 mock treatment 2520670.0 -659000.0 -0.56 2252371.0 -707000.0 -0.56 -0.7919 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E10 mock treatment 2349176.0 -831000.0 -0.7 2327777.0 -632000.0 -0.5 -0.8517 -0.9868 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E11 compound treatment 2342103.0 -838000.0 -0.71 2266766.0 -693000.0 -0.55 -0.8903 -0.9925 3632918 CBKinase1_023051 Fc1ccc(NC(=O)CSc2nnc(o2)c3ccncc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E12 compound treatment 2501461.0 -679000.0 -0.57 2612633.0 -347000.0 -0.28 -0.6003 -0.9443 3632919 CBKinase1_023052 COc1ccc(OC)c(NC(=O)CNC(=O)c2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E13 compound treatment 2511546.0 -669000.0 -0.56 2302481.0 -657000.0 -0.52 -0.7691 -0.9993 3632920 CBKinase1_023053 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E14 compound treatment 2273933.0 -906000.0 -0.76 2496946.0 -463000.0 -0.37 -0.8012 -0.9441 3632921 CBKinase1_023054 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E15 compound treatment 2238091.0 -942000.0 -0.79 2484232.0 -475000.0 -0.38 -0.8298 -0.9426 3632922 CBKinase1_023055 Cc1cc(nc(SCc2cccc(c2)C(=O)O)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E16 compound treatment 2433450.0 -747000.0 -0.63 2351583.0 -608000.0 -0.48 -0.788 -0.9916 3632923 CBKinase1_023056 Cc1cccc(Oc2coc3cc(OCC(=O)Nc4ccccc4C(F)(F)F)ccc3c2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E17 mock treatment 2325071.0 -855000.0 -0.72 2576954.0 -383000.0 -0.3 -0.7256 -0.9267 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E18 mock treatment 2751591.0 -429000.0 -0.36 2632469.0 -327000.0 -0.26 -0.44 -0.9871 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E19 compound treatment 2368535.0 -812000.0 -0.68 2366624.0 -593000.0 -0.47 -0.8183 -0.9836 3632924 CBKinase1_023057 COc1ccc(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E20 compound treatment 2305717.0 -874000.0 -0.74 2212657.0 -747000.0 -0.6 -0.9425 -0.9944 3632925 CBKinase1_023058 Cc1ccc(NS(=O)(=O)c2cc(ccc2C)C(=O)Nc3ccccc3C(=O)N4CCCC4)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E21 compound treatment 2142876.0 -1040000.0 -0.87 2337186.0 -622000.0 -0.5 -0.9694 -0.9639 3632926 CBKinase1_023059 Cc1ccc(cc1)c2cc(C)nc(SCC(=O)Nc3ccc(C)c(C)c3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E22 compound treatment 2053147.0 -1130000.0 -0.95 1938559.0 -1020000.0 -0.81 -1.2476 -0.997 3632927 CBKinase1_023060 CCN(CC(=O)Nc1ccc(F)c(Cl)c1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E23 compound treatment 2210531.0 -970000.0 -0.82 2246284.0 -713000.0 -0.57 -0.9803 -0.9842 3632928 CBKinase1_023061 Cc1cc(NC(=O)C(=O)NCCCN2CCOCC2)ccc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 E24 compound treatment 2106499.0 -1070000.0 -0.91 1977570.0 -982000.0 -0.78 -1.1938 -0.9974 3632929 CBKinase1_023062 Cc1cc(O)nc(SCC(=O)Nc2ccc(Br)cc2F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F01 mock treatment 1186338.0 -1990000.0 -1.68 1101374.0 -1860000.0 -1.48 -2.2365 -0.998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F02 mock treatment 1647404.0 -1530000.0 -1.29 1642887.0 -1320000.0 -1.05 -1.6563 -0.9946 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F03 compound treatment 1618415.0 -1560000.0 -1.32 1604359.0 -1360000.0 -1.08 -1.6953 -0.9951 3632930 CBKinase1_023063 Cc1sc(NC(=O)c2cnccn2)c(C(=O)N)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F04 compound treatment 1780670.0 -1400000.0 -1.18 1902258.0 -1060000.0 -0.84 -1.4306 -0.9864 3632931 CBKinase1_023064 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cc(Cl)ccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F05 compound treatment 1759041.0 -1420000.0 -1.2 1903089.0 -1060000.0 -0.84 -1.443 -0.9851 3632932 CBKinase1_023065 OC(=O)C1CC=CCC1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F06 compound treatment 1957346.0 -1220000.0 -1.03 1912354.0 -1050000.0 -0.83 -1.3195 -0.9945 3632933 CBKinase1_023066 Cc1cc(Br)ccc1NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F07 compound treatment 1983666.0 -1200000.0 -1.01 1967726.0 -992000.0 -0.79 -1.2726 -0.9927 3632934 CBKinase1_023067 NC(=O)CSCC(=O)Nc1ccccc1F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F08 compound treatment 2053805.0 -1130000.0 -0.95 2089495.0 -870000.0 -0.69 -1.1622 -0.988 3632935 CBKinase1_023068 Fc1ccc(NC(=O)CSc2nc3cc4ccccc4cc3[nH]2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F09 mock treatment 2312417.0 -868000.0 -0.73 2604902.0 -355000.0 -0.28 -0.7174 -0.9144 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F10 mock treatment 2353658.0 -826000.0 -0.7 2263108.0 -696000.0 -0.56 -0.8855 -0.9936 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F11 compound treatment 2237600.0 -943000.0 -0.8 2408045.0 -552000.0 -0.44 -0.873 -0.961 3632936 CBKinase1_023069 Cc1ccc(cc1)c2noc(CSc3nnc(c4ccccc4)n3C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F12 compound treatment 2308289.0 -872000.0 -0.74 2399021.0 -561000.0 -0.45 -0.8359 -0.9715 3632937 CBKinase1_023070 COc1ccc(Br)cc1CNCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F13 compound treatment 2265990.0 -914000.0 -0.77 2428332.0 -531000.0 -0.42 -0.8446 -0.9602 3632938 CBKinase1_023071 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc(OC)c(C)c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F14 compound treatment 2349674.0 -830000.0 -0.7 2149247.0 -810000.0 -0.65 -0.952 -0.9992 3632939 CBKinase1_023072 O=C(NCc1ccco1)c2cccnc2c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F15 compound treatment 2283410.0 -897000.0 -0.76 2243962.0 -716000.0 -0.57 -0.9382 -0.9903 3632940 CBKinase1_023073 Clc1ccc2OCC(=O)N(CC(=O)Nc3ccc4OCCOc4c3)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F16 compound treatment 2498003.0 -682000.0 -0.58 2263690.0 -696000.0 -0.55 -0.7991 -0.9998 3632941 CBKinase1_023074 Clc1ccccc1NC(=O)C2CC(=O)n3ncnc3N2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F17 mock treatment 2256264.0 -924000.0 -0.78 2434573.0 -525000.0 -0.42 -0.8469 -0.9575 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F18 mock treatment 2504513.0 -676000.0 -0.57 2193328.0 -766000.0 -0.61 -0.8348 -0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F19 compound treatment 2082587.0 -1100000.0 -0.93 2093043.0 -867000.0 -0.69 -1.143 -0.9896 3632942 CBKinase1_023075 COC(=O)c1ccccc1NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F20 compound treatment 1805526.0 -1370000.0 -1.16 2000372.0 -959000.0 -0.76 -1.3605 -0.9796 3632943 CBKinase1_023076 Cc1c(oc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccc(C)n4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F21 compound treatment 2042813.0 -1140000.0 -0.96 1860992.0 -1100000.0 -0.88 -1.2975 -0.999 3632944 CBKinase1_023077 [O-][N+](=O)c1ccc(cc1NCc2ccccn2)N3CCN(CC3)C(=O)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F22 compound treatment 2174319.0 -1010000.0 -0.85 2219409.0 -740000.0 -0.59 -1.0171 -0.9842 3632945 CBKinase1_023078 Cc1ccc(o1)C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F23 compound treatment 2053879.0 -1130000.0 -0.95 1725901.0 -1230000.0 -0.98 -1.367 -0.9999 3632946 CBKinase1_023079 Cc1ccc(CCNc2c(nn(c3ccc4OCCOc4c3)[n+]2[O-])[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 F24 compound treatment 1968894.0 -1210000.0 -1.02 1897748.0 -1060000.0 -0.85 -1.3209 -0.9956 3632947 CBKinase1_023080 Brc1ccc2oc(=O)c(cc2c1)C(=O)NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G01 compound treatment 2581114.0 -599000.0 -0.51 2123549.0 -836000.0 -0.67 -0.8285 -0.9907 3632948 CBKinase1_023081 Cc1cc(C)nc(Nc2n[nH]c(COc3ccccc3)n2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G02 compound treatment 2537491.0 -643000.0 -0.54 2409264.0 -550000.0 -0.44 -0.6935 -0.9945 3632949 CBKinase1_023082 COc1ccc2nc(O)c(CN(C)C(=O)c3cccc(Cl)c3)cc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G03 mock treatment 2810535.0 -370000.0 -0.31 2399964.0 -560000.0 -0.45 -0.5358 -0.9847 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G04 mock treatment 2897033.0 -283000.0 -0.24 2297276.0 -662000.0 -0.53 -0.5421 -0.9357 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G05 compound treatment 2780960.0 -399000.0 -0.34 2654999.0 -305000.0 -0.24 -0.4097 -0.9871 3632950 CBKinase1_023083 FC(F)(F)c1cccc(NC(=O)c2ccc(OCC(=O)Nc3cccc(Cl)c3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G06 compound treatment 2741337.0 -439000.0 -0.37 2461298.0 -498000.0 -0.4 -0.5425 -0.9994 3632951 CBKinase1_023084 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G07 compound treatment 2934522.0 -246000.0 -0.21 2603444.0 -356000.0 -0.28 -0.3472 -0.988 3632952 CBKinase1_023085 CCOC(=O)c1ccccc1NC(=O)C(C)Oc2cc(C)c(Cl)c(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G08 compound treatment 3051607.0 -129000.0 -0.11 3077192.0 118000.0 0.09 -0.0104 -0.0724 3040165 CBKinase1_023086 Cc1cc(C)nc(NCCCN2CCOCC2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G09 compound treatment 3005018.0 -175000.0 -0.15 2932822.0 -26800.0 -0.02 -0.1195 -0.8009 3632953 CBKinase1_023087 Fc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G10 compound treatment 2989746.0 -190000.0 -0.16 3010452.0 50900.0 0.04 -0.0849 -0.5125 3632954 CBKinase1_023088 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G11 compound treatment 2960606.0 -220000.0 -0.19 2712627.0 -247000.0 -0.2 -0.2701 -0.9995 3632955 CBKinase1_023089 Cc1cc(ccc1NC(=O)CSc2nccc(=O)[nH]2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G12 compound treatment 3061330.0 -119000.0 -0.1 2699315.0 -260000.0 -0.21 -0.2175 -0.9443 3632956 CBKinase1_023090 FC(F)(F)C(NC(=O)NCCCn1ccnc1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G13 compound treatment 2656495.0 -524000.0 -0.44 2981615.0 22000.0 0.02 -0.2999 -0.6785 3632957 CBKinase1_023091 Nc1n[nH]c(SCC(=O)NC2CCCCC2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G14 compound treatment 2704428.0 -476000.0 -0.4 2711530.0 -248000.0 -0.2 -0.4235 -0.9468 3632958 CBKinase1_023092 Cc1[nH]c2ccccc2c1C(=O)CSc3nc4sc5CCCc5c4c(=O)n3c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G15 compound treatment 3038848.0 -141000.0 -0.12 2898169.0 -61400.0 -0.05 -0.1189 -0.9228 3632959 CBKinase1_023093 Cc1cccc(OCCCC(=O)Nc2ccccc2[N+](=O)[O-])c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G16 compound treatment 2884821.0 -295000.0 -0.25 2692297.0 -267000.0 -0.21 -0.3268 -0.997 3632960 CBKinase1_023094 CC1(C)CC2=C(C(=O)C1)C(NC(=O)C3CCCCC3)(C(=O)N2Cc4ccco4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G17 compound treatment 2971388.0 -209000.0 -0.18 3037198.0 77600.0 0.06 -0.0808 -0.4328 3632961 CBKinase1_023095 Cc1ccccc1NC(=O)CSc2nc3cc4ccccc4cc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G18 compound treatment 2872451.0 -308000.0 -0.26 2822559.0 -137000.0 -0.11 -0.2607 -0.926 3124987 CBKinase1_023096 CC(C)N(Cc1cc2ccc(C)cc2nc1O)C(=O)c3cccc(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G19 mock treatment 2698045.0 -482000.0 -0.41 2677620.0 -282000.0 -0.22 -0.4465 -0.9609 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G20 mock treatment 2603399.0 -577000.0 -0.49 2617909.0 -342000.0 -0.27 -0.5366 -0.9624 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G21 compound treatment 2947991.0 -232000.0 -0.2 2487654.0 -472000.0 -0.38 -0.4044 -0.9537 3632962 CBKinase1_023097 Cc1cccc(NC(=O)CSc2nnc3n(C)c4ccccc4n23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G22 compound treatment 2499871.0 -680000.0 -0.57 2481773.0 -478000.0 -0.38 -0.675 -0.9802 3632963 CBKinase1_023098 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3cccc(Cl)c3Cl)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G23 compound treatment 2486237.0 -694000.0 -0.59 2501551.0 -458000.0 -0.37 -0.672 -0.9742 3632964 CBKinase1_023099 CCOc1cc(C)c(Cl)cc1S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 G24 compound treatment 2344442.0 -836000.0 -0.7 2244872.0 -715000.0 -0.57 -0.9012 -0.9944 3632965 CBKinase1_023100 CCOC(=O)c1c(NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2)sc4CCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H01 compound treatment 2431333.0 -749000.0 -0.63 2249339.0 -710000.0 -0.57 -0.8469 -0.9985 3632966 CBKinase1_023101 Cc1cc(cs1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccc(C)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H02 compound treatment 2933175.0 -247000.0 -0.21 2975828.0 16200.0 0.01 -0.1381 -0.6619 3632967 CBKinase1_023102 COC(=O)c1ccccc1NC(=O)Cn2cnc3sc(C)c(C)c3c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H03 mock treatment 2961232.0 -219000.0 -0.18 2867252.0 -92300.0 -0.07 -0.1826 -0.9187 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H04 mock treatment 2872880.0 -307000.0 -0.26 3152916.0 193000.0 0.15 -0.0743 -0.2464 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H05 compound treatment 3067811.0 -112000.0 -0.09 3031872.0 72300.0 0.06 -0.0263 -0.2368 3632968 CBKinase1_023103 Cc1onc(c1C(=O)NCCCN2CCOCC2)c3c(F)cccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H06 compound treatment 2964866.0 -215000.0 -0.18 3068502.0 109000.0 0.09 -0.067 -0.333 3632969 CBKinase1_023104 CCOc1cc(C)c(Cl)cc1S(=O)(=O)n2nnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H07 compound treatment 3358932.0 179000.0 0.15 3263689.0 304000.0 0.24 0.278 0.9739 3632970 CBKinase1_023105 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H08 compound treatment 3124266.0 -55900.0 -0.05 2979598.0 20000.0 0.02 -0.022 -0.4431 3632971 CBKinase1_023106 Cc1cc(OCC(=O)Nc2cccc3ncccc23)cc(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H09 compound treatment 3013390.0 -167000.0 -0.14 3139728.0 180000.0 0.14 0.0021 0.0103 3632972 CBKinase1_023107 Oc1cc(CSCC(=O)Nc2ccc(F)cc2)n[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H10 compound treatment 3175795.0 -4330.0 0.0 3375755.0 416000.0 0.33 0.232 0.6993 3632973 CBKinase1_023108 COc1ccc(cc1Cl)S(=O)(=O)N(CC(=O)Nc2ccccc2)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H11 compound treatment 3380562.0 200000.0 0.17 3146381.0 187000.0 0.15 0.2248 0.998 3632974 CBKinase1_023109 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4cccnc4)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H12 compound treatment 3264194.0 84100.0 0.07 3243069.0 283000.0 0.23 0.2099 0.8864 3632975 CBKinase1_023110 Cc1ccccc1n2c(SCC(=O)N)nc3ccccc3c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H13 compound treatment 2986547.0 -194000.0 -0.16 3245408.0 286000.0 0.23 0.0456 0.1628 3632976 CBKinase1_023111 CCC(=O)N1CCN(CC1)c2ccc(Cl)cc2NC(=O)COc3cc(C)cc(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H14 compound treatment 3061015.0 -119000.0 -0.1 3425044.0 465000.0 0.37 0.1913 0.4977 3632977 CBKinase1_023112 COc1ccc(NCC(O)Cn2ccc3ccccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H15 compound treatment 3320157.0 140000.0 0.12 3027622.0 68000.0 0.05 0.1219 0.9376 3632978 CBKinase1_023113 CC(=O)NCCc1nc2cc(NC(=O)Nc3ccccc3)ccc2n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H16 compound treatment 3226389.0 46300.0 0.04 3216020.0 256000.0 0.2 0.1721 0.8272 3040112 CBKinase1_023114 Cc1cc(C)nc(Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H17 compound treatment 3364923.0 185000.0 0.16 3389546.0 430000.0 0.34 0.3525 0.9364 3632979 CBKinase1_023115 Cc1ccc(cc1)c2nnc(SCC(=O)c3cccc(c3)[N+](=O)[O-])n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H18 compound treatment 3346013.0 166000.0 0.14 3338634.0 379000.0 0.3 0.3126 0.9388 3632980 CBKinase1_023116 COc1ccc(NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H19 mock treatment 2887972.0 -292000.0 -0.25 3157119.0 198000.0 0.16 -0.0629 -0.2152 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H20 mock treatment 3483478.0 303000.0 0.26 2752874.0 -207000.0 -0.16 0.0644 0.2117 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H21 compound treatment 3105871.0 -74300.0 -0.06 2900403.0 -59200.0 -0.05 -0.0776 -0.9902 3632981 CBKinase1_023117 COc1cccc(c1)C(=O)N(Cc2nc(no2)c3ccc(C)cc3)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H22 compound treatment 3098643.0 -81500.0 -0.07 3232157.0 273000.0 0.22 0.105 0.4609 3632982 CBKinase1_023118 Cc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3onc(C)c3C)c(C)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H23 compound treatment 2999521.0 -181000.0 -0.15 2773730.0 -186000.0 -0.15 -0.2125 -0.9999 3632983 CBKinase1_023119 CC(=O)c1cccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 H24 compound treatment 2608668.0 -571000.0 -0.48 2704770.0 -255000.0 -0.2 -0.4845 -0.9262 3632984 CBKinase1_023120 CC1(CC1(Cl)Cl)C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I01 compound treatment 2250039.0 -930000.0 -0.78 1900798.0 -1060000.0 -0.84 -1.1515 -0.9993 3632985 CBKinase1_023121 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I02 compound treatment 2618015.0 -562000.0 -0.47 2588175.0 -371000.0 -0.3 -0.5446 -0.9743 3632986 CBKinase1_023122 Cc1ccc(NC(=O)CSc2nc(N)n[nH]2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I03 compound treatment 3023817.0 -156000.0 -0.13 2964167.0 4570.0 0.0 -0.0907 -0.6873 3632987 CBKinase1_023123 COc1cccc(OCc2nc(no2)c3ccc(OC)c(OC)c3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I04 compound treatment 2703925.0 -476000.0 -0.4 2972371.0 12800.0 0.01 -0.2768 -0.689 1428486 CBKinase1_023124 Cc1cc(Cl)ccc1NC(=O)COc2ccc(cc2)C(=O)Nc3cc(Cl)ccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I05 mock treatment 2804341.0 -376000.0 -0.32 2870734.0 -88900.0 -0.07 -0.2742 -0.8443 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I06 mock treatment 2895253.0 -285000.0 -0.24 2817771.0 -142000.0 -0.11 -0.2498 -0.9408 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I07 compound treatment 3371727.0 192000.0 0.16 3187969.0 228000.0 0.18 0.243 0.9982 3632988 CBKinase1_023125 Cc1[nH]c2ccccc2c1C(=O)CSc3nc(C)cc(C)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I08 compound treatment 3313051.0 133000.0 0.11 3117288.0 158000.0 0.13 0.1682 0.9984 3632989 CBKinase1_023126 Nc1cc(O)nc(SCC(=O)Nc2ccc(Br)cc2Cl)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I09 compound treatment 3175952.0 -4170.0 0.0 3217256.0 258000.0 0.21 0.1427 0.6949 3632990 CBKinase1_023127 CC(=O)Nc1ccc(cc1)C(=O)CSc2nc(cs2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I10 compound treatment 3164872.0 -15300.0 -0.01 3142492.0 183000.0 0.15 0.094 0.6422 3632991 CBKinase1_023128 [O-][N+](=O)c1ccc(NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I11 compound treatment 3262765.0 82600.0 0.07 3308771.0 349000.0 0.28 0.2461 0.8577 3632992 CBKinase1_023129 Cc1cc(nc(SCC(=O)Nc2sc3CCCCc3c2C#N)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I12 compound treatment 2859006.0 -321000.0 -0.27 3381216.0 422000.0 0.34 0.0461 0.1068 3632993 CBKinase1_023130 COc1ccc(cc1)c2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I13 compound treatment 3478696.0 299000.0 0.25 3344351.0 385000.0 0.31 0.3949 0.9952 3632994 CBKinase1_023131 CCN(CC(=O)Nc1cccc(SC)c1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I14 compound treatment 3234399.0 54300.0 0.05 3449614.0 490000.0 0.39 0.3085 0.7846 3632995 CBKinase1_023132 [O-][N+](=O)c1cccc(NC(=O)CN2C(=O)C3C4CC(C(C4)C3C2=O)c5ccccc5)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I15 compound treatment 3170330.0 -9790.0 -0.01 3470752.0 511000.0 0.41 0.2822 0.6926 3632996 CBKinase1_023133 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2(C(=O)N(C3CCCCC3)C(=C2C(=O)C)C)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I16 compound treatment 3352830.0 173000.0 0.15 3263943.0 304000.0 0.24 0.2745 0.9702 3632997 CBKinase1_023134 COc1ccc(cc1)c2cc(C)nc(SCC(=O)Nc3cccc(Cl)c3Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I17 compound treatment 2620201.0 -560000.0 -0.47 2481483.0 -478000.0 -0.38 -0.6034 -0.9943 3632998 CBKinase1_023135 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3ccc(cc3)c4nc5ccc(C)cc5s4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I18 compound treatment 3439879.0 260000.0 0.22 3256330.0 297000.0 0.24 0.3222 0.9993 3632999 CBKinase1_023136 Cc1cc(OCCCC(=O)Nc2sc3CCCCc3c2C#N)cc(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I19 compound treatment 3263242.0 83100.0 0.07 3156705.0 197000.0 0.16 0.1607 0.9339 3633000 CBKinase1_023137 COc1ccc(NC(=O)CSc2nc(cs2)C(C)(C)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I20 compound treatment 3200837.0 20700.0 0.02 3077768.0 118000.0 0.09 0.079 0.8242 3633001 CBKinase1_023138 Clc1ccc(cc1C(=O)NCc2ccccn2)n3cnnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I21 mock treatment 3005843.0 -174000.0 -0.15 2861631.0 -98000.0 -0.08 -0.1592 -0.9562 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I22 mock treatment 3142611.0 -37500.0 -0.03 3378095.0 419000.0 0.33 0.2135 0.6372 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I23 compound treatment 2929659.0 -250000.0 -0.21 2979743.0 20100.0 0.02 -0.138 -0.6515 3633002 CBKinase1_023139 CCc1ccccc1NC(=O)Cn2c(nc3ccccc23)c4nonc4N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 I24 compound treatment 2446043.0 -734000.0 -0.62 2348430.0 -611000.0 -0.49 -0.7823 -0.9929 3633003 CBKinase1_023140 Fc1ccccc1NC(=O)COc2ccc3c(=O)c(Oc4ccc(cc4)c5ccccc5)coc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J01 compound treatment 2950568.0 -230000.0 -0.19 2726052.0 -234000.0 -0.19 -0.2685 -0.9998 3633004 CBKinase1_023141 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J02 compound treatment 3033820.0 -146000.0 -0.12 2780397.0 -179000.0 -0.14 -0.1883 -0.9974 3633005 CBKinase1_023142 COc1ccc(OC)c(NC(=O)COc2ccc3c(cc(=O)oc3c2)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J03 compound treatment 3098869.0 -81300.0 -0.07 2968156.0 8560.0 0.01 -0.0436 -0.6336 3633006 CBKinase1_023143 O=C(Nc1sccc1C(=O)N2CCOCC2)c3cc4ccccc4oc3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J04 compound treatment 3175537.0 -4590.0 0.0 3005421.0 45800.0 0.04 0.0231 0.6287 3633007 CBKinase1_023144 Cc1ccc(NC(=O)CSc2nnc(c3ccccc3F)n2C)cc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J05 mock treatment 3185262.0 5140.0 0.0 3224707.0 265000.0 0.21 0.1525 0.7215 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J06 mock treatment 3079113.0 -101000.0 -0.09 2878360.0 -81200.0 -0.06 -0.106 -0.9908 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J07 compound treatment 3458897.0 279000.0 0.24 3459558.0 500000.0 0.4 0.448 0.9683 3633008 CBKinase1_023145 COc1cc(cc(Br)c1OCC(=O)N)c2nc3ccccc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J08 compound treatment 3617794.0 438000.0 0.37 3281060.0 321000.0 0.26 0.4422 0.9841 3633009 CBKinase1_023146 Cn1nnc(NC(=O)CSc2nnnn2c3ccc(F)cc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J09 compound treatment 2576573.0 -604000.0 -0.51 3450381.0 491000.0 0.39 -0.0834 -0.1299 3633010 CBKinase1_023147 Cn1nnnc1SCCNCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J10 compound treatment 3243349.0 63200.0 0.05 3309461.0 350000.0 0.28 0.2349 0.8273 3633011 CBKinase1_023148 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2c(C)cccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J11 compound treatment 3070043.0 -110000.0 -0.09 3431753.0 472000.0 0.38 0.2004 0.5171 3633012 CBKinase1_023149 COC(=O)c1cc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J12 compound treatment 3660181.0 480000.0 0.4 3552122.0 593000.0 0.47 0.6203 0.9971 3041321 CBKinase1_023150 COc1ccc2nc(O)c(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J13 compound treatment 3229350.0 49200.0 0.04 3341346.0 382000.0 0.3 0.2445 0.7962 3633013 CBKinase1_023151 CCOc1ccccc1NC(=O)Cc2coc3ccc(C)cc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J14 compound treatment 3807585.0 627000.0 0.53 3210017.0 250000.0 0.2 0.5154 0.9111 3633014 CBKinase1_023152 Oc1ccccc1c2nnc(SCC(=O)N3CCc4ccccc34)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J15 compound treatment 3742586.0 562000.0 0.47 3436648.0 477000.0 0.38 0.6043 0.994 3633015 CBKinase1_023153 CCCn1cnc2cc(NCc3ccccn3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J16 compound treatment 3276042.0 95900.0 0.08 3757288.0 798000.0 0.64 0.5068 0.7907 3633016 CBKinase1_023154 COc1ccc(cc1)C(=O)NCC(=O)Nc2cc(OC)ccc2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J17 compound treatment 3849311.0 669000.0 0.56 3579199.0 620000.0 0.49 0.7483 0.9978 3633017 CBKinase1_023155 COc1ccc(C)cc1S(=O)(=O)N2CCCC(C2)C(=O)Nc3cccc(SC)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J18 compound treatment 3480978.0 301000.0 0.25 3274148.0 315000.0 0.25 0.3567 1.0 3633018 CBKinase1_023156 Cc1ccc(cc1N(CC(=O)O)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J19 compound treatment 3561516.0 381000.0 0.32 3125571.0 166000.0 0.13 0.321 0.9229 3633019 CBKinase1_023157 O=C(NCCc1c[nH]c2ccccc12)NC3(CC4CC5CC(C4)C3)C5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J20 compound treatment 3317377.0 137000.0 0.12 3450895.0 491000.0 0.39 0.3588 0.8786 3633020 CBKinase1_023158 CC(=O)Nc1cccc(Cn2cccn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J21 mock treatment 3343551.0 163000.0 0.14 3427437.0 468000.0 0.37 0.3611 0.9084 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J22 mock treatment 3290851.0 111000.0 0.09 3465027.0 505000.0 0.4 0.3509 0.8485 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J23 compound treatment 3245847.0 65700.0 0.06 3139071.0 179000.0 0.14 0.1404 0.9148 3633021 CBKinase1_023159 COc1ccc(Cl)cc1NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 J24 compound treatment 2866720.0 -313000.0 -0.26 2790658.0 -169000.0 -0.13 -0.2821 -0.951 3633022 CBKinase1_023160 Clc1ccc2oc(=O)c(cc2c1)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K01 compound treatment 1561618.0 -1620000.0 -1.37 1448353.0 -1510000.0 -1.2 -1.8171 -0.9981 1459275 CBKinase1_023161 OC(=O)CN(c1ccc2OCCOc2c1)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K02 compound treatment 2902652.0 -277000.0 -0.23 2460955.0 -499000.0 -0.4 -0.4465 -0.9681 3633023 CBKinase1_023162 COCCNS(=O)(=O)c1ccc(F)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K03 compound treatment 3070047.0 -110000.0 -0.09 2670496.0 -289000.0 -0.23 -0.2286 -0.9201 1506532 CBKinase1_023163 O=C(CSc1nnc(c2ccccc2)n1c3ccccc3)N4c5ccccc5Sc6ccccc46 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K04 compound treatment 3451399.0 271000.0 0.23 2959236.0 -357.0 0.0 0.1616 0.7062 3633024 CBKinase1_023164 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K05 compound treatment 3122386.0 -57700.0 -0.05 2788472.0 -171000.0 -0.14 -0.1309 -0.9037 3633025 CBKinase1_023165 CCOc1cc(ccc1F)S(=O)(=O)n2nnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K06 compound treatment 3109846.0 -70300.0 -0.06 2671172.0 -288000.0 -0.23 -0.2045 -0.8613 3633026 CBKinase1_023166 Oc1cc(=O)nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K07 mock treatment 2934336.0 -246000.0 -0.21 3068041.0 108000.0 0.09 -0.0855 -0.3805 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K08 mock treatment 2997052.0 -183000.0 -0.15 2663579.0 -296000.0 -0.24 -0.276 -0.9789 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K09 compound treatment 3216324.0 36200.0 0.03 2703949.0 -256000.0 -0.2 -0.1225 -0.5945 1633061 CBKinase1_023167 CCOc1ccc(NC(=O)Cn2cnc3scc(c4ccc(C)cc4)c3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K10 compound treatment 3428694.0 249000.0 0.21 2692402.0 -267000.0 -0.21 -0.0023 -0.0078 1337149 CBKinase1_023168 COc1ccc(NC(=O)c2ccc(OCC(=O)Nc3cccc(C)c3C)cc2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K11 compound treatment 2800254.0 -380000.0 -0.32 3392794.0 433000.0 0.35 0.0176 0.0373 3633027 CBKinase1_023169 COc1cccc(CNc2nn[nH]n2)c1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K12 compound treatment 3083351.0 -96800.0 -0.08 2954229.0 -5360.0 0.0 -0.0607 -0.7431 3633028 CBKinase1_023170 COc1ccc(cc1NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K13 compound treatment 3168044.0 -12100.0 -0.01 2972377.0 12800.0 0.01 0.0 0.0 1532513 CBKinase1_023171 Cc1ccc(NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K14 compound treatment 3194018.0 13900.0 0.01 2837753.0 -122000.0 -0.1 -0.0604 -0.6173 3633029 CBKinase1_023172 O=C(Cn1cnc2sc(cc2c1=O)c3ccccc3)Nc4sc5CCCc5c4C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K15 mock treatment 3425701.0 246000.0 0.21 3359097.0 400000.0 0.32 0.3716 0.9783 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K16 mock treatment 3375569.0 195000.0 0.16 3340477.0 381000.0 0.3 0.3312 0.9588 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K17 compound treatment 3520070.0 340000.0 0.29 3330819.0 371000.0 0.3 0.412 0.9999 3633030 CBKinase1_023173 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccc(Cl)cc3Cl)(C(=O)N2Cc4ccco4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K18 compound treatment 1260782.0 -1920000.0 -1.62 1649500.0 -1310000.0 -1.04 -1.8831 -0.9775 1867202 CBKinase1_023174 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2c(CN3CCOCC3)cc(Cl)c4cccnc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K19 compound treatment 2994953.0 -185000.0 -0.16 3183404.0 224000.0 0.18 0.0157 0.0662 3633031 CBKinase1_023175 COc1ccc(CCNS(=O)(=O)c2cc(C)ccc2OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K20 compound treatment 3065225.0 -115000.0 -0.1 2944901.0 -14700.0 -0.01 -0.0768 -0.7868 3633032 CBKinase1_023176 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)NC(C)(C(F)(F)F)C(F)(F)F)cc2)no1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K21 compound treatment 3000735.0 -179000.0 -0.15 3197431.0 238000.0 0.19 0.027 0.1115 3633033 CBKinase1_023177 CN(C)c1nc(N)nc(CSc2nnc([nH]2)c3ccccc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K22 compound treatment 3241891.0 61800.0 0.05 3179742.0 220000.0 0.18 0.1609 0.8791 3633034 CBKinase1_023178 COc1ccc(cc1)c2cc(C)nc(SCC(=O)Nc3ccccc3F)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K23 mock treatment 2877792.0 -302000.0 -0.26 2804847.0 -155000.0 -0.12 -0.2675 -0.9444 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 K24 mock treatment 3187415.0 7290.0 0.01 2657397.0 -302000.0 -0.24 -0.166 -0.6888 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L01 compound treatment 3003697.0 -176000.0 -0.15 2656468.0 -303000.0 -0.24 -0.2761 -0.9729 3633035 CBKinase1_023179 CC(=O)Nc1sccc1C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L02 compound treatment 2739870.0 -440000.0 -0.37 3094127.0 135000.0 0.11 -0.1868 -0.4832 3633036 CBKinase1_023180 Clc1cc(ccc1OCC(=O)Nc2ccccc2)S(=O)(=O)N3CCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L03 compound treatment 2778521.0 -402000.0 -0.34 2851817.0 -108000.0 -0.09 -0.3003 -0.8592 3633037 CBKinase1_023181 CCOC(=O)CNC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(Cl)s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L04 compound treatment 3210110.0 30000.0 0.03 2951293.0 -8300.0 -0.01 0.0132 0.5052 3633038 CBKinase1_023182 Cc1ccccc1NS(=O)(=O)c2cc(ccc2C)C(=O)NCC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L05 compound treatment 3239657.0 59500.0 0.05 2852423.0 -107000.0 -0.09 -0.0249 -0.2512 3633039 CBKinase1_023183 Cc1c(oc2ccccc12)C(=O)Nc3cnccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L06 compound treatment 3109791.0 -70300.0 -0.06 2899428.0 -60200.0 -0.05 -0.0759 -0.9944 3633040 CBKinase1_023184 CCN(CC(=O)Nc1ccc(F)c(Cl)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L07 mock treatment 3873587.0 693000.0 0.58 3227438.0 268000.0 0.21 0.5646 0.9067 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L08 mock treatment 3643893.0 464000.0 0.39 3256714.0 297000.0 0.24 0.4441 0.9711 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L09 compound treatment 3479573.0 299000.0 0.25 3162472.0 203000.0 0.16 0.2929 0.9768 3633041 CBKinase1_023185 COc1ccccc1c2noc(CCC(=O)Nc3ccccc3C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L10 compound treatment 3758435.0 578000.0 0.49 3627716.0 668000.0 0.53 0.7215 0.999 3633042 CBKinase1_023186 Cc1nc(nc(SCC(=O)O)c1Cc2ccccc2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L11 compound treatment 3405862.0 226000.0 0.19 3202064.0 242000.0 0.19 0.2713 1.0 3633043 CBKinase1_023187 Cc1cc(ccc1NC(=O)CN2C(=O)COc3ccc(Cl)cc23)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L12 compound treatment 3752818.0 573000.0 0.48 3691470.0 732000.0 0.58 0.7541 0.9956 3633044 CBKinase1_023188 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L13 compound treatment 3887110.0 707000.0 0.6 3493336.0 534000.0 0.43 0.7225 0.9863 3633045 CBKinase1_023189 COC(=O)c1ccccc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L14 compound treatment 3841622.0 661000.0 0.56 3584515.0 625000.0 0.5 0.7467 0.9984 3633046 CBKinase1_023190 COC(=O)C(O)(c1ccc(NC(=S)NC(=O)c2ccc(Cl)cc2Cl)c(OC)c1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L15 mock treatment 3812093.0 632000.0 0.53 3454597.0 495000.0 0.39 0.6559 0.989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L16 mock treatment 4243134.0 1060000.0 0.9 3861899.0 902000.0 0.72 1.1426 0.994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L17 compound treatment 4324859.0 1140000.0 0.97 3776979.0 817000.0 0.65 1.1434 0.9817 3633047 CBKinase1_023191 Cc1cccc(NC(=O)CCc2nc(no2)c3ccc(Cl)cc3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L18 compound treatment 4292088.0 1110000.0 0.94 3774184.0 815000.0 0.65 1.1223 0.9839 3633048 CBKinase1_023192 COc1ccc(CNCCSc2nnnn2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L19 compound treatment 3996427.0 816000.0 0.69 3654989.0 695000.0 0.55 0.8788 0.9942 3633049 CBKinase1_023193 CCn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4ccccc4F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L20 compound treatment 3827051.0 647000.0 0.55 3731534.0 772000.0 0.62 0.8209 0.9982 3633050 CBKinase1_023194 O=C(NCCCN1CCCC1=O)c2cc3ccccc3oc2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L21 compound treatment 3601567.0 421000.0 0.36 3334146.0 375000.0 0.3 0.4625 0.9962 3633051 CBKinase1_023195 Cc1cc(=O)n2c3ccccc3n(CC(O)CNc4ccccc4)c2c1C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L22 compound treatment 4066656.0 887000.0 0.75 3571097.0 612000.0 0.49 0.8734 0.9785 3633052 CBKinase1_023196 COc1ccccc1CCNC(=O)c2c(C)onc2c3c(F)cccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L23 mock treatment 3653803.0 474000.0 0.4 3639929.0 680000.0 0.54 0.666 0.9887 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 L24 mock treatment 3631517.0 451000.0 0.38 2565088.0 -395000.0 -0.31 0.0469 0.095 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M01 compound treatment 2961976.0 -218000.0 -0.18 2458507.0 -501000.0 -0.4 -0.4125 -0.9381 3633053 CBKinase1_023197 COc1cc(ccc1Br)S(=O)(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M02 compound treatment 2706228.0 -474000.0 -0.4 2377336.0 -582000.0 -0.46 -0.6108 -0.9972 3633054 CBKinase1_023198 COc1ccc(C)cc1S(=O)(=O)N(CC(=O)N)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M03 compound treatment 2920056.0 -260000.0 -0.22 2461172.0 -498000.0 -0.4 -0.436 -0.9608 3633055 CBKinase1_023199 COc1ccc2nc(NCc3ccc(OC)c(OC)c3OC)sc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M04 compound treatment 2968454.0 -212000.0 -0.18 2609899.0 -350000.0 -0.28 -0.3233 -0.9768 3633056 CBKinase1_023200 COc1ccc(cc1I)S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M05 compound treatment 3171427.0 -8700.0 -0.01 2590076.0 -370000.0 -0.29 -0.2134 -0.7245 3633057 CBKinase1_023201 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M06 compound treatment 3050889.0 -129000.0 -0.11 2724435.0 -235000.0 -0.19 -0.2096 -0.9667 3633058 CBKinase1_023202 OC(=O)CCc1ccc(c2cccs2)n1CC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M07 compound treatment 3822295.0 642000.0 0.54 3149847.0 190000.0 0.15 0.4902 0.8716 3633059 CBKinase1_023203 Cc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(cc3)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M08 compound treatment 3630422.0 450000.0 0.38 2882457.0 -77100.0 -0.06 0.2251 0.585 3633060 CBKinase1_023204 COc1ccc(cc1OC)C(=O)NCC(=O)Nc2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M09 mock treatment 3517586.0 337000.0 0.28 3244154.0 285000.0 0.23 0.3617 0.9937 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M10 mock treatment 3870666.0 691000.0 0.58 3389418.0 430000.0 0.34 0.6541 0.968 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M11 compound treatment 3472941.0 293000.0 0.25 3160401.0 201000.0 0.16 0.2878 0.9779 3633061 CBKinase1_023205 Cc1c(oc2ccccc12)C(=O)Nc3nnc(SC/C=C/c4ccccc4)s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M12 compound treatment 3385702.0 206000.0 0.17 3209581.0 250000.0 0.2 0.2635 0.9976 3633063 CBKinase1_023206 OC(=O)c1cc(Nc2nc(nc(n2)N3CCOCC3)N4CCOCC4)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M13 mock treatment 3467695.0 288000.0 0.24 3107991.0 148000.0 0.12 0.2552 0.9455 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M14 mock treatment 3744725.0 565000.0 0.48 3382312.0 423000.0 0.34 0.575 0.9856 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M15 compound treatment 3007647.0 -172000.0 -0.15 2781086.0 -179000.0 -0.14 -0.2035 -0.9999 3633064 CBKinase1_023207 COC(=O)c1ccccc1NC(=O)Cn2c(C)ccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M16 compound treatment 3849166.0 669000.0 0.56 3445315.0 486000.0 0.39 0.6728 0.9831 3633065 CBKinase1_023208 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)cc1)c2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M17 compound treatment 3780587.0 600000.0 0.51 3710310.0 751000.0 0.6 0.7812 0.9966 3633066 CBKinase1_023209 COC(=O)c1ccc(NC(=O)CSc2nnnn2C3CC4CCC3C4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M18 compound treatment 4028861.0 849000.0 0.72 3220510.0 261000.0 0.21 0.6533 0.8763 1072357 CBKinase1_023210 [O-][N+](=O)c1ccccc1CC(=O)CC#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M19 compound treatment 3679220.0 499000.0 0.42 3207874.0 248000.0 0.2 0.4376 0.9407 3633067 CBKinase1_023211 Cc1c(oc2ccc(F)cc12)C(=O)Nc3nnc(SCc4cccc(C)c4)s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M20 compound treatment 3447255.0 267000.0 0.23 2926448.0 -33100.0 -0.03 0.1406 0.62 3633068 CBKinase1_023212 COc1ccc(C)cc1S(=O)(=O)N(CC(=O)O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M21 compound treatment 3435336.0 255000.0 0.22 2738303.0 -221000.0 -0.18 0.0275 0.0988 3633069 CBKinase1_023213 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(SC)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M22 compound treatment 3461375.0 281000.0 0.24 2824866.0 -135000.0 -0.11 0.0918 0.3526 3633070 CBKinase1_023214 COc1ccc(NC(=O)CSc2nc(N)n[nH]2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M23 compound treatment 3066492.0 -114000.0 -0.1 2538972.0 -421000.0 -0.34 -0.3048 -0.8742 3633071 CBKinase1_023215 CCOc1ccc(cc1S(=O)(=O)n2c(C)nc3ccccc23)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 M24 compound treatment 3082464.0 -97700.0 -0.08 2502572.0 -457000.0 -0.36 -0.3158 -0.8457 3633072 CBKinase1_023216 FC(F)(F)c1ccc(Cl)c(NC(=O)COc2ccc3c(cc(=O)oc3c2)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N01 compound treatment 2947952.0 -232000.0 -0.2 2221131.0 -738000.0 -0.59 -0.5547 -0.8942 3633073 CBKinase1_023217 Cc1noc(C)c1C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N02 compound treatment 2429267.0 -751000.0 -0.63 2453568.0 -506000.0 -0.4 -0.733 -0.9763 3633074 CBKinase1_023218 CC(Oc1cccc(Br)c1)C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N03 compound treatment 3213837.0 33700.0 0.03 2824693.0 -135000.0 -0.11 -0.0559 -0.5028 3633075 CBKinase1_023219 COc1ccccc1C(=O)NCCCn2cc(Br)c(C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N04 compound treatment 2900019.0 -280000.0 -0.24 2814543.0 -145000.0 -0.12 -0.2488 -0.9459 3633076 CBKinase1_023220 Oc1ccccc1c2nnc(SCC(=O)Nc3ccc4OCCOc4c3)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N05 compound treatment 3142911.0 -37200.0 -0.03 2871805.0 -87800.0 -0.07 -0.0717 -0.9346 2061459 CBKinase1_023221 O=C(NCCCn1ccnc1)c2cc3CCCCc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N06 compound treatment 2913023.0 -267000.0 -0.23 2755031.0 -205000.0 -0.16 -0.2746 -0.9874 3633077 CBKinase1_023222 CSc1cccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N07 compound treatment 3994891.0 815000.0 0.69 3090552.0 131000.0 0.1 0.5598 0.8053 3633078 CBKinase1_023223 COc1ccc(C)cc1S(=O)(=O)N(CC(=O)O)c2cc(C)cc(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N08 compound treatment 3622031.0 442000.0 0.37 2963689.0 4100.0 0.0 0.2659 0.7133 3633079 CBKinase1_023224 Cc1nn2c(CN(C(=O)CN3CCOCC3)c4ccccc4)nnc2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N09 mock treatment 3423010.0 243000.0 0.2 3051890.0 92300.0 0.07 0.1969 0.9045 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N10 mock treatment 3493740.0 314000.0 0.26 3321805.0 362000.0 0.29 0.3912 0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N11 compound treatment 3392035.0 212000.0 0.18 3088067.0 128000.0 0.1 0.1988 0.965 3633080 CBKinase1_023225 CC(C(=O)Nc1ccc(C)c(C)c1)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N12 compound treatment 3626036.0 446000.0 0.38 3317371.0 358000.0 0.29 0.4676 0.9907 3633081 CBKinase1_023226 OC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)Nc3cccc(c3)C(F)(F)F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N13 mock treatment 3127285.0 -52800.0 -0.04 3370209.0 411000.0 0.33 0.1999 0.6052 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N14 mock treatment 2899544.0 -281000.0 -0.24 3496484.0 537000.0 0.43 0.1352 0.2766 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N15 compound treatment 3798659.0 619000.0 0.52 3388552.0 429000.0 0.34 0.6107 0.979 1122747 CBKinase1_023227 C(Sc1nc(c[nH]1)c2ccccc2)c3nc4ccccc4[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N16 compound treatment 3574332.0 394000.0 0.33 3613427.0 654000.0 0.52 0.6036 0.9764 3633082 CBKinase1_023228 Fc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N17 compound treatment 3703462.0 523000.0 0.44 3368313.0 409000.0 0.33 0.5425 0.9888 3633083 CBKinase1_023229 COc1ccc2[nH]cc(CCNC(=O)Nc3ccc(Cl)c(Cl)c3)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N18 compound treatment 2538079.0 -642000.0 -0.54 3616629.0 657000.0 0.52 -0.0126 -0.0168 3633084 CBKinase1_023230 Cn1c(SCC(=O)Nc2ccc(cc2)C(=O)O)nnc1c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N19 compound treatment 3713799.0 534000.0 0.45 3111220.0 152000.0 0.12 0.4038 0.8663 3633085 CBKinase1_023231 CN(c1cccc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3ccc(C)cc3C)c1)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N20 compound treatment 3060911.0 -119000.0 -0.1 3235408.0 276000.0 0.22 0.0843 0.3489 3633086 CBKinase1_023232 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)C3CCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N21 compound treatment 3949902.0 770000.0 0.65 2991133.0 31500.0 0.03 0.4769 0.7339 3633087 CBKinase1_023233 [O-][N+](=O)c1cccc(NC(=O)CCc2nc(no2)c3ccccc3Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N22 compound treatment 3364295.0 184000.0 0.16 2712715.0 -247000.0 -0.2 -0.0293 -0.1168 3633088 CBKinase1_023234 Cc1occc1C(=O)Nc2cccc(Cn3cccn3)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N23 compound treatment 3352181.0 172000.0 0.15 3061967.0 102000.0 0.08 0.1603 0.9629 3633089 CBKinase1_023235 CCCn1c(SCc2nc(no2)c3cccs3)nnc1c4ccncc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 N24 compound treatment 3283554.0 103000.0 0.09 2277869.0 -682000.0 -0.54 -0.3225 -0.5861 3633090 CBKinase1_023236 CCOc1cccc2cc(C(=O)NCc3cccnc3)c(=O)oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O01 compound treatment 3315914.0 136000.0 0.11 2470959.0 -489000.0 -0.39 -0.1944 -0.4789 3633091 CBKinase1_023237 Cc1nn2c(CN(C(=O)c3cccs3)c4ccccc4)nnc2c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O02 compound treatment 3301785.0 122000.0 0.1 2607921.0 -352000.0 -0.28 -0.1256 -0.4209 3633092 CBKinase1_023238 COC(=O)c1ccccc1NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O03 compound treatment 3444826.0 265000.0 0.22 3210397.0 251000.0 0.2 0.2992 0.9985 3633093 CBKinase1_023239 CC(C)OC(=O)c1sc2ncn(CC(=O)Nc3ccccc3C(F)(F)F)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O04 compound treatment 3264635.0 84500.0 0.07 3284228.0 325000.0 0.26 0.2334 0.8695 3633094 CBKinase1_023240 CCOc1cc(ccc1O)C2N=C(Nc3nc4ccccc4o3)NC5=C2C(=O)CC(C)(C)C5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O05 compound treatment 3353867.0 174000.0 0.15 2441584.0 -518000.0 -0.41 -0.1883 -0.4298 3633095 CBKinase1_023241 FC(F)(F)C1(N=C(CCc2ccccc2)Nc3c1c(=O)[nH]c(=O)n3Cc4ccco4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O06 compound treatment 3271603.0 91500.0 0.08 2900955.0 -58600.0 -0.05 0.0215 0.2385 3633096 CBKinase1_023242 [O-][N+](=O)c1ccc(cc1NCc2ccccn2)N3CCNCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O07 compound treatment 3775445.0 595000.0 0.5 3350836.0 391000.0 0.31 0.5756 0.9737 3633097 CBKinase1_023243 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O08 compound treatment 3194943.0 14800.0 0.01 3043800.0 84200.0 0.07 0.0563 0.8246 1868461 CBKinase1_023244 Cc1ccc2c(CC(=O)Nc3cccc(c3)[N+](=O)[O-])coc2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O09 compound treatment 3180065.0 -59.2 0.0 3247165.0 288000.0 0.23 0.162 0.707 3633098 CBKinase1_023245 Cc1cc(O)nc(SCC(=O)Nc2c(C)cccc2C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O10 compound treatment 3640031.0 460000.0 0.39 3217578.0 258000.0 0.21 0.4197 0.9559 3633099 CBKinase1_023246 Cc1cc(nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O11 mock treatment 3692184.0 512000.0 0.43 3214273.0 255000.0 0.2 0.449 0.9407 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O12 mock treatment 3545819.0 366000.0 0.31 3783188.0 824000.0 0.66 0.6823 0.9407 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O13 compound treatment 3798895.0 619000.0 0.52 3299696.0 340000.0 0.27 0.5607 0.9534 3633100 CBKinase1_023247 OC1(CC(=O)c2cccnc2)C(=O)N(CCc3ccccc3)c4ccc(Br)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O14 compound treatment 4096055.0 916000.0 0.77 4075589.0 1120000.0 0.89 1.1753 0.9975 3633101 CBKinase1_023248 Cc1[nH]c2ccccc2c1C(=O)CSc3n[nH]c(N)n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O15 compound treatment 4235919.0 1060000.0 0.89 3837751.0 878000.0 0.7 1.1246 0.9929 3633102 CBKinase1_023249 COc1ccccc1C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccc(C)cc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O16 compound treatment 4308023.0 1130000.0 0.95 3924751.0 965000.0 0.77 1.2167 0.9944 3633103 CBKinase1_023250 CCOc1cc(ccc1F)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O17 compound treatment 4499751.0 1320000.0 1.11 4168260.0 1210000.0 0.96 1.4683 0.9974 3633104 CBKinase1_023251 COc1ccc(cc1)S(=O)(=O)N(C)c2ccc(cc2)C(=O)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O18 compound treatment 4401574.0 1220000.0 1.03 3985347.0 1030000.0 0.82 1.3066 0.9934 3633105 CBKinase1_023252 CCOC(=O)c1ccc(COC(=O)c2ccc3ccccc3c2O)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O19 compound treatment 4176005.0 996000.0 0.84 3682594.0 723000.0 0.58 1.0015 0.9831 3633106 CBKinase1_023253 FC(F)(F)c1cccc(NC(=O)CNC(=O)c2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O20 compound treatment 4195367.0 1020000.0 0.86 3272907.0 313000.0 0.25 0.7821 0.8768 3633107 CBKinase1_023254 COC(=O)c1ccccc1NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O21 compound treatment 3710068.0 530000.0 0.45 3547703.0 588000.0 0.47 0.6475 0.9997 3633108 CBKinase1_023255 CC(=O)C1=C(C)N(CC2CCCO2)C(=O)C1(NC(=O)c3ccc(cc3)C(C)(C)C)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O22 compound treatment 3389379.0 209000.0 0.18 3183763.0 224000.0 0.18 0.2511 1.0 3633109 CBKinase1_023256 COc1cccc(c1)C(=O)NC2(C(=O)N(CC3CCCO3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O23 compound treatment 3500517.0 320000.0 0.27 3154888.0 195000.0 0.16 0.3012 0.9657 3633110 CBKinase1_023257 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 O24 compound treatment 3250110.0 70000.0 0.06 2767880.0 -192000.0 -0.15 -0.0663 -0.4048 3633111 CBKinase1_023258 COC(=O)c1ccccc1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)Nc3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P01 compound treatment 2867574.0 -313000.0 -0.26 1901718.0 -1060000.0 -0.84 -0.7826 -0.8859 3633112 CBKinase1_023259 FC(F)(F)c1cccc(OCC(=O)NCc2cccnc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P02 compound treatment 2486263.0 -694000.0 -0.59 1691939.0 -1270000.0 -1.01 -1.1283 -0.9663 3633113 CBKinase1_023260 Cc1[nH]c2ccccc2c1C(=O)CSc3nc(cs3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P03 compound treatment 2479583.0 -701000.0 -0.59 2451189.0 -508000.0 -0.41 -0.7044 -0.9831 3633114 CBKinase1_023261 CCOc1ccc2ccccc2c1C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P04 compound treatment 2681981.0 -498000.0 -0.42 2603265.0 -356000.0 -0.28 -0.4979 -0.9818 3633115 CBKinase1_023262 C(Oc1ccc(cc1)c2nnn[nH]2)c3nnn[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P05 compound treatment 3369957.0 190000.0 0.16 2311977.0 -648000.0 -0.52 -0.2518 -0.4659 3633116 CBKinase1_023263 O=C(Nc1sccc1C(=O)N2CCOCC2)c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P06 compound treatment 2911705.0 -268000.0 -0.23 2503307.0 -456000.0 -0.36 -0.4173 -0.974 3633117 CBKinase1_023264 CCOc1cc(C)c(Cl)cc1S(=O)(=O)n2cnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P07 compound treatment 3175355.0 -4770.0 0.0 2333864.0 -626000.0 -0.5 -0.3555 -0.7128 3633118 CBKinase1_023265 Cc1nn(CC(=O)Nc2ccc(F)cc2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P08 compound treatment 3105586.0 -74500.0 -0.06 3073666.0 114000.0 0.09 0.0198 0.1794 3633119 CBKinase1_023266 CCn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P09 compound treatment 3466255.0 286000.0 0.24 2886242.0 -73400.0 -0.06 0.1293 0.5208 3633120 CBKinase1_023267 COc1ccccc1NC(=O)CN2C(=O)NC(C)(C)C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P10 compound treatment 3103647.0 -76500.0 -0.06 2879809.0 -79800.0 -0.06 -0.0906 -1.0 3633121 CBKinase1_023268 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc(Br)c(C)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P11 mock treatment 3639896.0 460000.0 0.39 3140266.0 181000.0 0.14 0.3761 0.909 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P12 mock treatment 3389649.0 210000.0 0.18 2886841.0 -72800.0 -0.06 0.084 0.4514 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P13 compound treatment 3682857.0 503000.0 0.42 2820357.0 -139000.0 -0.11 0.2214 0.505 3633122 CBKinase1_023269 COc1ccc(OC)c(NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(C)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P14 compound treatment 3669961.0 490000.0 0.41 3235765.0 276000.0 0.22 0.4478 0.9565 3633123 CBKinase1_023270 COc1cccc2cc(C(=O)CC3(O)C(=O)N(Cc4ccccc4)c5ccc(Br)cc53)c(=O)oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P15 compound treatment 3667709.0 488000.0 0.41 3575226.0 616000.0 0.49 0.6378 0.9961 3633124 CBKinase1_023271 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)Cc4coc5cc(C)cc(C)c45)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P16 compound treatment 3784982.0 605000.0 0.51 1988730.0 -971000.0 -0.77 -0.1864 -0.2011 3633125 CBKinase1_023272 CSc1nsc(SCC(=O)Nc2ccc(cc2)C(=O)C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P17 compound treatment 4349127.0 1170000.0 0.99 3542078.0 582000.0 0.46 1.0255 0.941 3633126 CBKinase1_023273 CSc1nc2ccc(cc2s1)S(=O)(=O)NCCOc3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P18 compound treatment 4341233.0 1160000.0 0.98 3930920.0 971000.0 0.77 1.24 0.9932 3633127 CBKinase1_023274 Cc1occc1C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P19 compound treatment 3693047.0 513000.0 0.43 3503433.0 544000.0 0.43 0.6124 1.0 3633128 CBKinase1_023275 Cc1ccc(o1)C(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P20 compound treatment 3817906.0 638000.0 0.54 3512391.0 553000.0 0.44 0.692 0.9951 3633129 CBKinase1_023276 Cc1sc(NC(=O)c2ccco2)c(C(=O)NCc3cccnc3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P21 compound treatment 3920844.0 741000.0 0.62 3396551.0 437000.0 0.35 0.6881 0.9619 3633130 CBKinase1_023277 C(c1nnc2sc(nn12)c3ccccc3)n4cnc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P22 compound treatment 3592017.0 412000.0 0.35 3168983.0 209000.0 0.17 0.3637 0.9436 3633131 CBKinase1_023278 Cc1sc(NC(=O)COc2cc(C)ccc2Cl)c(C(=O)N)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P23 compound treatment 3449116.0 269000.0 0.23 3066581.0 107000.0 0.09 0.2207 0.9107 3633132 CBKinase1_023279 OC(=O)c1cc(CC(=O)Nc2ccccc2)nc3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2396 P24 compound treatment 3061643.0 -118000.0 -0.1 4341820.0 1380000.0 1.1 0.7083 0.6403 3633133 CBKinase1_023280 COC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A01 compound treatment 2103280.0 -836000.0 -0.7 1651218.0 -1330000.0 -1.06 -1.2452 -0.9807 3633134 CBKinase1_023281 CNC(=O)CCc1nc(no1)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A02 compound treatment 2092482.0 -846000.0 -0.71 2674603.0 -302000.0 -0.24 -0.6749 -0.8958 1662124 CBKinase1_023282 Oc1ccccc1C(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A03 compound treatment 2103532.0 -835000.0 -0.7 1540551.0 -1440000.0 -1.14 -1.3074 -0.9729 3633135 CBKinase1_023283 CC(CCc1ccccc1)Nc2c(nn(c3ccccc3)[n+]2[O-])[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A04 compound treatment 2720417.0 -218000.0 -0.18 2763035.0 -213000.0 -0.17 -0.2505 -0.9992 3633136 CBKinase1_023284 CN(C)c1nc(N)nc(CSc2nc3cc(Cl)ccc3o2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A05 compound treatment 3600434.0 662000.0 0.56 3041140.0 64900.0 0.05 0.4311 0.7693 3633137 CBKinase1_023285 Cc1nc2ncnn2c(O)c1NS(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A06 compound treatment 2444949.0 -494000.0 -0.42 2624897.0 -351000.0 -0.28 -0.4927 -0.9813 3633138 CBKinase1_023286 Cc1ccc(c(c1)S(=O)(=O)N2CCOCC2)n3cnnn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A07 compound treatment 2330836.0 -608000.0 -0.51 2332784.0 -644000.0 -0.51 -0.7254 -1.0 3633139 CBKinase1_023287 CCOC(=O)COc1cccc(c1)c2nc3ccccc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A08 compound treatment 2532651.0 -406000.0 -0.34 2332697.0 -644000.0 -0.51 -0.605 -0.9808 3633140 CBKinase1_023288 COc1cccc(c1)C2CC(n3nc(cc3N2)C(=O)Nc4cc(C)nn4c5ccccc5)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A09 compound treatment 2706177.0 -233000.0 -0.2 2698929.0 -277000.0 -0.22 -0.2951 -0.9982 3633141 CBKinase1_023289 OC(=O)c1cc(NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A10 compound treatment 3014397.0 75500.0 0.06 2674741.0 -302000.0 -0.24 -0.1249 -0.5025 3633142 CBKinase1_023290 Cc1ccc(o1)C(=O)CCNc2ccc3c(c2)oc4ccccc43 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A11 compound treatment 2955620.0 16700.0 0.01 2792667.0 -184000.0 -0.15 -0.0935 -0.6361 3633143 CBKinase1_023291 COc1cccc(NC(=O)CCc2nc(no2)c3ccccc3Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A12 compound treatment 2983907.0 45000.0 0.04 2803082.0 -173000.0 -0.14 -0.0708 -0.4944 3633144 CBKinase1_023292 CN1CCN(CC1)C(=O)CCc2nc(no2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A13 mock treatment 2966613.0 27700.0 0.02 2790145.0 -186000.0 -0.15 -0.0884 -0.5885 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A14 mock treatment 3019541.0 80600.0 0.07 2837792.0 -138000.0 -0.11 -0.03 -0.2311 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A15 compound treatment 3213172.0 274000.0 0.23 2771679.0 -205000.0 -0.16 0.0483 0.1705 3633145 CBKinase1_023293 CCC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccccc3C(=O)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A16 compound treatment 3529804.0 591000.0 0.5 3001205.0 24900.0 0.02 0.3665 0.7347 3633146 CBKinase1_023294 COC(=O)c1cc(NC(=O)CSc2nc(Nc3ccccc3)nc(n2)N4CCOCC4)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A17 compound treatment 2926051.0 -12900.0 -0.01 2766530.0 -210000.0 -0.17 -0.1259 -0.7514 3633147 CBKinase1_023295 CCn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A18 compound treatment 3117973.0 179000.0 0.15 2930504.0 -45800.0 -0.04 0.081 0.5213 3633148 CBKinase1_023296 Cn1c(SCC(=O)c2cc3ccccc3o2)nnc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A19 compound treatment 3723664.0 785000.0 0.66 3403993.0 428000.0 0.34 0.7091 0.9524 3633149 CBKinase1_023297 O=C(COc1ccc(cc1)S(=O)(=O)N2CCCCC2)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A20 compound treatment 3411171.0 472000.0 0.4 3734789.0 759000.0 0.6 0.7092 0.9795 3633150 CBKinase1_023298 Cc1cc(C)n2nc(SCC(=O)Nc3cccc(c3)C(F)(F)F)nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A21 compound treatment 3449288.0 510000.0 0.43 3344426.0 368000.0 0.29 0.5119 0.9825 3633151 CBKinase1_023299 Oc1ccccc1c2nnc(SCC(=O)Nc3ccccc3C#N)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A22 compound treatment 3704292.0 765000.0 0.65 3475853.0 500000.0 0.4 0.7381 0.973 3633152 CBKinase1_023300 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)NCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A23 compound treatment 3168586.0 230000.0 0.19 2818781.0 -158000.0 -0.13 0.0482 0.2089 3633153 CBKinase1_023301 COc1ccc(OC)c(NC(=O)COc2ccc3c4CCCc4c(=O)oc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 A24 compound treatment 2522995.0 -416000.0 -0.35 2547679.0 -429000.0 -0.34 -0.4896 -0.9999 3633154 CBKinase1_023302 NC(=O)CSc1oc(nc1S(=O)(=O)c2ccc(Br)cc2)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B01 compound treatment 2824574.0 -114000.0 -0.1 3142686.0 166000.0 0.13 0.0256 0.156 3633155 CBKinase1_023303 CCN(CC(=O)Nc1cccc(F)c1)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B02 compound treatment 3108425.0 170000.0 0.14 2861373.0 -115000.0 -0.09 0.0363 0.214 3633156 CBKinase1_023304 CCOc1ccccc1NC(=O)c2ccsc2NC(=O)c3cc4ccccc4oc3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B03 compound treatment 3111241.0 172000.0 0.15 3234819.0 259000.0 0.21 0.2485 0.9854 3633157 CBKinase1_023305 Cc1ccccc1Cn2ccc(NC(=O)c3nn4C(CC(Nc4c3Cl)c5ccccc5)C(F)(F)F)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B04 compound treatment 3461514.0 523000.0 0.44 4160177.0 1180000.0 0.94 0.9789 0.9399 3633158 CBKinase1_023306 FC(F)(F)c1cccc(OCC(=O)Nc2cccnc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B05 compound treatment 3875943.0 937000.0 0.79 2972736.0 -3550.0 0.0 0.5569 0.7046 3633159 CBKinase1_023307 COc1ccc(cc1)c2cc(nc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B06 compound treatment 3756452.0 818000.0 0.69 4233676.0 1260000.0 1.0 1.1963 0.9834 3633160 CBKinase1_023308 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B07 compound treatment 3037677.0 98800.0 0.08 3623435.0 647000.0 0.52 0.4236 0.8108 3633161 CBKinase1_023309 C(c1nnc2sc(nn12)c3cccs3)n4cnc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B08 compound treatment 3453458.0 515000.0 0.43 3161360.0 185000.0 0.15 0.4112 0.897 3633162 CBKinase1_023310 COC(=O)c1c(NC(=O)c2ccccc2[N+](=O)[O-])scc1c3cccc(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B09 compound treatment 3314564.0 376000.0 0.32 3447858.0 472000.0 0.38 0.4898 0.9964 3633163 CBKinase1_023311 COc1ccc(cc1NC(=O)COc2ccc(Cl)cc2Cl)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B10 compound treatment 3364985.0 426000.0 0.36 3273740.0 297000.0 0.24 0.4218 0.9796 3633164 CBKinase1_023312 CCc1ccccc1NC(=O)C(C)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B11 compound treatment 3667537.0 729000.0 0.61 3532209.0 556000.0 0.44 0.7479 0.9871 1577636 CBKinase1_023313 COC(=O)c1ccc2c(=O)n(CCc3c[nH]cn3)c(=S)[nH]c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B12 compound treatment 4192102.0 1250000.0 1.06 3885625.0 909000.0 0.72 1.26 0.9831 3633165 CBKinase1_023314 Cc1ccc(c2nc3cc(NC(=O)COc4ccccc4Cl)ccc3o2)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B13 mock treatment 3713759.0 775000.0 0.65 3876992.0 901000.0 0.72 0.9698 0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B14 mock treatment 3817665.0 879000.0 0.74 3358996.0 383000.0 0.31 0.7398 0.923 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B15 compound treatment 3995113.0 1060000.0 0.89 3730120.0 754000.0 0.6 1.0548 0.9816 3633166 CBKinase1_023315 Cc1cc(no1)C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B16 compound treatment 4028869.0 1090000.0 0.92 3760351.0 784000.0 0.62 1.092 0.9823 3633167 CBKinase1_023316 CCN(CC(=O)Nc1cccc(Cl)c1C)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B17 compound treatment 3973237.0 1030000.0 0.87 3555448.0 579000.0 0.46 0.9433 0.9557 3633168 CBKinase1_023317 CC(=O)c1ccccc1NS(=O)(=O)c2c(C)nn(c2C)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B18 compound treatment 4007147.0 1070000.0 0.9 3890900.0 915000.0 0.73 1.1526 0.9945 3633169 CBKinase1_023318 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B19 compound treatment 4805012.0 1870000.0 1.57 4287253.0 1310000.0 1.04 1.8519 0.9802 3633170 CBKinase1_023319 COc1ccccc1CCNC(=O)c2ccoc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B20 compound treatment 4488320.0 1550000.0 1.31 4225198.0 1250000.0 1.0 1.628 0.991 3125409 CBKinase1_023320 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccccn5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B21 compound treatment 4590324.0 1650000.0 1.39 4097883.0 1120000.0 0.89 1.6171 0.977 3633171 CBKinase1_023321 Cc1cc(cs1)C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B22 compound treatment 4112203.0 1170000.0 0.99 3957346.0 981000.0 0.78 1.2527 0.9932 3633172 CBKinase1_023322 CCc1ccc(NC(=O)CC2Nc3cc(C)c(C)cc3NC2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B23 compound treatment 4187497.0 1250000.0 1.05 3837713.0 861000.0 0.69 1.2302 0.9785 3633173 CBKinase1_023323 COC(=O)c1ccsc1NC(=O)c2ccsc2NC(=O)c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 B24 compound treatment 3362341.0 423000.0 0.36 2739116.0 -237000.0 -0.19 0.1189 0.2942 3633174 CBKinase1_023324 CC(C)N(Cc1nc(no1)c2ccccc2Cl)C(=O)c3ccccc3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C01 compound treatment 2619041.0 -320000.0 -0.27 2171323.0 -805000.0 -0.64 -0.6445 -0.9259 3633175 CBKinase1_023325 COc1ccccc1C(=O)Nc2ccc3n(C)c(CCNC(=O)C)nc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C02 compound treatment 2610827.0 -328000.0 -0.28 2230129.0 -746000.0 -0.59 -0.6162 -0.9394 3633176 CBKinase1_023326 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C03 compound treatment 2708936.0 -230000.0 -0.19 2442410.0 -534000.0 -0.43 -0.4381 -0.9367 3633177 CBKinase1_023327 Oc1ccc(Oc2nc(nc(n2)N3CCOCC3)N4CCCCC4)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C04 compound treatment 2581661.0 -357000.0 -0.3 2485069.0 -491000.0 -0.39 -0.4899 -0.9916 3633178 CBKinase1_023328 CS(=O)(=O)N(CC(=O)NC1CCCCCC1)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C05 compound treatment 3104456.0 166000.0 0.14 2611684.0 -365000.0 -0.29 -0.1068 -0.3311 3633179 CBKinase1_023329 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nc3cc(Cl)ccc3o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C06 compound treatment 3185441.0 247000.0 0.21 2607837.0 -368000.0 -0.29 -0.0606 -0.1685 3633180 CBKinase1_023330 O=C(CSc1nnc(Nc2ccccc2)n1c3ccccc3)Nc4ccc5C(=O)OCc5c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C07 compound treatment 2862375.0 -76500.0 -0.06 2541649.0 -435000.0 -0.35 -0.2906 -0.8247 3633181 CBKinase1_023331 COC(=O)c1ccc(NC(=O)CN2C(=O)CN(C2=O)c3ccc(Br)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C08 compound treatment 2672117.0 -267000.0 -0.23 2887647.0 -88600.0 -0.07 -0.2091 -0.8864 3633182 CBKinase1_023332 COCCNC(=O)c1ccccc1c2nc(no2)c3ccc(OC)c(OC)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C09 compound treatment 3060162.0 121000.0 0.1 2868029.0 -108000.0 -0.09 0.0113 0.0845 1772764 CBKinase1_023333 O=C(NCc1ccco1)C2CCCN(C2)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C10 compound treatment 2962784.0 23900.0 0.02 3125024.0 149000.0 0.12 0.0981 0.8155 3633183 CBKinase1_023334 CC(Oc1ccc(Cl)cc1C)C(=O)Nc2cccc(c2)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C11 mock treatment 3110670.0 172000.0 0.14 2913194.0 -63100.0 -0.05 0.0669 0.4361 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C12 mock treatment 2909384.0 -29500.0 -0.02 3114343.0 138000.0 0.11 0.0602 0.5336 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C13 compound treatment 2996129.0 57200.0 0.05 3027847.0 51600.0 0.04 0.0632 0.9968 3633184 CBKinase1_023335 Cc1cc(ccc1[N+](=O)[O-])C(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C14 compound treatment 3239721.0 301000.0 0.25 2959417.0 -16900.0 -0.01 0.1699 0.6687 3633185 CBKinase1_023336 CCn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C15 mock treatment 3107286.0 168000.0 0.14 3083262.0 107000.0 0.09 0.1607 0.9702 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C16 mock treatment 2950280.0 11400.0 0.01 2980755.0 4470.0 0.0 0.0093 0.909 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C17 compound treatment 3104248.0 165000.0 0.14 2822606.0 -154000.0 -0.12 0.012 0.0646 3633186 CBKinase1_023337 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3cnn(c3)C4(CC5CC6CC(C5)C4)C6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C18 compound treatment 3200205.0 261000.0 0.22 3057266.0 81000.0 0.06 0.2015 0.8773 3633187 CBKinase1_023338 CCOc1ccc(NC(=O)CSc2nc3nc(C)cc(C)n3n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C19 compound treatment 3461384.0 522000.0 0.44 3274251.0 298000.0 0.24 0.4796 0.9579 3633188 CBKinase1_023339 CCCC(=O)Nc1ccc2C(=O)N(CCC(=O)O)C(=O)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C20 compound treatment 3300022.0 361000.0 0.3 3354611.0 378000.0 0.3 0.4286 1.0 3633189 CBKinase1_023340 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C21 compound treatment 3054410.0 115000.0 0.1 3361768.0 385000.0 0.31 0.2861 0.8878 3633190 CBKinase1_023341 Cc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccccc4)C(F)(F)F)nn1CC(=O)N5CCOCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C22 compound treatment 3079604.0 141000.0 0.12 3134320.0 158000.0 0.13 0.173 0.9996 3633191 CBKinase1_023342 CC(Oc1cccc(Cl)c1)C(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C23 compound treatment 2531651.0 -407000.0 -0.34 2478773.0 -498000.0 -0.4 -0.5233 -0.9974 3633192 CBKinase1_023343 Cc1cc2c(=O)n(Cc3ccco3)c(SCC(=O)c4ccc(Cl)s4)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 C24 compound treatment 2417859.0 -521000.0 -0.44 2401481.0 -575000.0 -0.46 -0.6347 -0.9998 3633193 CBKinase1_023344 Clc1ccccc1C2=NOC(C2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D01 compound treatment 2533565.0 -405000.0 -0.34 2466962.0 -509000.0 -0.41 -0.5288 -0.9964 3633194 CBKinase1_023345 Nc1cc(N)nc(SCc2n[nH]c(=S)n2c3ccccc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D02 compound treatment 2852527.0 -86400.0 -0.07 3460150.0 484000.0 0.39 0.2212 0.5635 3633195 CBKinase1_023346 COC(=O)Nc1sc2CCCCc2c1C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D03 compound treatment 3033915.0 95000.0 0.08 2845567.0 -131000.0 -0.1 -0.017 -0.1294 3633196 CBKinase1_023347 COc1ccccc1NC(=O)CCc2nc(no2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D04 compound treatment 3648460.0 710000.0 0.6 3215886.0 240000.0 0.19 0.5582 0.8886 3633197 CBKinase1_023348 O=C(NCCCN1CCCC1=O)c2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D05 compound treatment 2763020.0 -176000.0 -0.15 3557498.0 581000.0 0.46 0.2227 0.4577 3633198 CBKinase1_023349 Cc1nnc(SCc2ccc(o2)C(=O)c3ccc(Cl)cc3)n1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D06 compound treatment 3212236.0 273000.0 0.23 3417870.0 442000.0 0.35 0.4119 0.979 3633199 CBKinase1_023350 O=C(Nc1ccc(cc1)S(=O)(=O)NC(=O)c2ccccc2)C3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D07 compound treatment 1528405.0 -1410000.0 -1.19 1513185.0 -1460000.0 -1.17 -1.6659 -0.9999 3633200 CBKinase1_023351 COc1ccc(OC)c(CNc2c(nn(c3ccc(Cl)cc3)[n+]2[O-])[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D08 compound treatment 3356637.0 418000.0 0.35 3378499.0 402000.0 0.32 0.4758 0.9989 3633201 CBKinase1_023352 COc1ccc(cc1[N+](=O)[O-])C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D09 compound treatment 3281062.0 342000.0 0.29 3191218.0 215000.0 0.17 0.3252 0.969 3633202 CBKinase1_023353 Cc1nnc2c3ccccc3c(nn12)c4ccc(C)c(c4)S(=O)(=O)NCCN5CCOCC5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D10 compound treatment 2930362.0 -8550.0 -0.01 3006325.0 30000.0 0.02 0.0118 0.4731 3633203 CBKinase1_023354 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4ccco4)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D11 mock treatment 3372572.0 434000.0 0.37 3467858.0 492000.0 0.39 0.5357 0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D12 mock treatment 3540252.0 601000.0 0.51 3326179.0 350000.0 0.28 0.5559 0.9603 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D13 compound treatment 3322650.0 384000.0 0.32 3510107.0 534000.0 0.43 0.5297 0.9909 3633204 CBKinase1_023355 Cn1c(SCc2nc(no2)c3cccs3)nnc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D14 compound treatment 3510959.0 572000.0 0.48 3135995.0 160000.0 0.13 0.4312 0.8641 3633205 CBKinase1_023356 Cc1ccc(cc1)n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D15 mock treatment 3353490.0 415000.0 0.35 3347191.0 371000.0 0.3 0.4563 0.9965 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D16 mock treatment 3555674.0 617000.0 0.52 3384368.0 408000.0 0.33 0.5979 0.9744 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D17 compound treatment 3260076.0 321000.0 0.27 3646612.0 670000.0 0.53 0.5693 0.9504 3633206 CBKinase1_023357 CC(=O)c1ccccc1NC(=O)C2C(C3CCC2O3)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D18 compound treatment 3665268.0 726000.0 0.61 3344682.0 368000.0 0.29 0.6409 0.9433 3633207 CBKinase1_023358 CC1CCc2c(C1)sc3ncnc(NCCc4nc5ccccc5[nH]4)c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D19 compound treatment 3788173.0 849000.0 0.72 3628852.0 653000.0 0.52 0.8743 0.9876 3633208 CBKinase1_023359 Cc1ccc(cc1C)c2cc(n3nc(cc3n2)C(=O)NCCCn4ccnc4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D20 compound treatment 3414068.0 475000.0 0.4 3787022.0 811000.0 0.65 0.7403 0.9736 3633209 CBKinase1_023360 Cc1cc2c(=O)n(Cc3ccco3)c(SCC(=O)c4cc5ccccc5o4)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D21 compound treatment 3182557.0 244000.0 0.21 2956904.0 -19400.0 -0.02 0.1344 0.6521 3633210 CBKinase1_023361 Cc1sc(NC(=O)COc2ccccc2)c(C(=O)N)c1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D22 compound treatment 3182892.0 244000.0 0.21 3215363.0 239000.0 0.19 0.2803 0.9993 3633211 CBKinase1_023362 COc1ccc(c2ccccc12)S(=O)(=O)NCCc3c[nH]c4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D23 compound treatment 2943412.0 4500.0 0.0 3040292.0 64000.0 0.05 0.0388 0.7576 3633212 CBKinase1_023363 Cc1cc(nn1CCCNC(=O)c2cccs2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 D24 compound treatment 2592811.0 -346000.0 -0.29 2558431.0 -418000.0 -0.33 -0.4419 -0.9978 3633213 CBKinase1_023364 COC(=O)CN(c1cc(ccc1OC)[N+](=O)[O-])S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E01 mock treatment 803017.0 -2140000.0 -1.8 944742.0 -2030000.0 -1.62 -2.4189 -0.9986 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E02 mock treatment 1031212.0 -1910000.0 -1.61 1075587.0 -1900000.0 -1.51 -2.2091 -0.9995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E03 compound treatment 1072590.0 -1870000.0 -1.57 1411755.0 -1560000.0 -1.25 -1.9949 -0.9933 3633214 CBKinase1_023365 FC(F)(F)c1cccc(NC(=O)CSc2nc(c(C#N)c(=O)[nH]2)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E04 compound treatment 1434631.0 -1500000.0 -1.27 1367696.0 -1610000.0 -1.28 -1.8038 -1.0 1849833 CBKinase1_023366 OC(=O)c1cc(NC(=O)CSc2nnnn2c3ccccc3)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E05 compound treatment 1267461.0 -1670000.0 -1.41 1546458.0 -1430000.0 -1.14 -1.8028 -0.9944 3633215 CBKinase1_023367 Cc1ccc(cc1)c2noc(CCC(=O)NC(C)(C)C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E06 compound treatment 1540026.0 -1400000.0 -1.18 1912889.0 -1060000.0 -0.85 -1.4337 -0.9868 3633216 CBKinase1_023368 CSc1cccc(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E07 compound treatment 1395540.0 -1540000.0 -1.3 1487398.0 -1490000.0 -1.19 -1.7597 -0.9989 3633217 CBKinase1_023369 NC(=O)CSc1oc(nc1S(=O)(=O)c2ccc(Cl)cc2)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E08 compound treatment 1234167.0 -1700000.0 -1.44 2149207.0 -827000.0 -0.66 -1.4829 -0.9375 3633218 CBKinase1_023370 Cc1ccc(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E09 mock treatment 1902053.0 -1040000.0 -0.87 2154836.0 -821000.0 -0.65 -1.0814 -0.9898 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E10 mock treatment 1879390.0 -1060000.0 -0.89 1933616.0 -1040000.0 -0.83 -1.2196 -0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E11 compound treatment 1928663.0 -1010000.0 -0.85 2004767.0 -972000.0 -0.77 -1.1501 -0.9989 3633219 CBKinase1_023371 CCc1cc(c2n[nH]c(C(=O)O)c2c3nc(C)cs3)c(O)cc1O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E12 compound treatment 1962268.0 -977000.0 -0.82 2324948.0 -651000.0 -0.52 -0.9496 -0.9752 3633220 CBKinase1_023372 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E13 compound treatment 1881920.0 -1060000.0 -0.89 1969082.0 -1010000.0 -0.8 -1.1981 -0.9986 3633221 CBKinase1_023373 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E14 compound treatment 933621.0 -2010000.0 -1.69 821181.0 -2160000.0 -1.72 -2.4106 -1.0 3633222 CBKinase1_023374 [O-][N+](=O)c1nn(c2ccc(Cl)cc2)[n+]([O-])c1NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E15 compound treatment 2272449.0 -666000.0 -0.56 2369925.0 -606000.0 -0.48 -0.7392 -0.9972 3633223 CBKinase1_023375 CC(Sc1ncnc2sc3CCCCc3c12)C(=O)Nc4cc(ccc4Cl)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E16 compound treatment 2242473.0 -696000.0 -0.59 2438194.0 -538000.0 -0.43 -0.7187 -0.988 3633224 CBKinase1_023376 CCn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E17 mock treatment 2485522.0 -453000.0 -0.38 2302154.0 -674000.0 -0.54 -0.6504 -0.9861 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E18 mock treatment 2651971.0 -287000.0 -0.24 2521436.0 -455000.0 -0.36 -0.4275 -0.9807 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E19 compound treatment 2447478.0 -491000.0 -0.41 2777058.0 -199000.0 -0.16 -0.4054 -0.9133 3633225 CBKinase1_023377 CC(=O)NCCc1nc2cc(ccc2n1C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E20 compound treatment 2199254.0 -740000.0 -0.62 2163868.0 -812000.0 -0.65 -0.899 -0.9998 3633226 CBKinase1_023378 Cc1cc(ccc1Br)N(CC(=O)NC2CC3CCC2C3)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E21 compound treatment 2530684.0 -408000.0 -0.34 1913972.0 -1060000.0 -0.85 -0.8422 -0.9214 3633227 CBKinase1_023379 CC(C)N(Cc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E22 compound treatment 2036087.0 -903000.0 -0.76 2266254.0 -710000.0 -0.57 -0.9387 -0.9893 3633228 CBKinase1_023380 CC1(C)C2(C)CCC1(OC2=O)C(=O)NCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E23 compound treatment 2158316.0 -781000.0 -0.66 2365250.0 -611000.0 -0.49 -0.81 -0.989 3633229 CBKinase1_023381 Cc1ccc(cc1)c2noc(CCC(=O)Nc3ccccc3[N+](=O)[O-])n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 E24 compound treatment 2038667.0 -900000.0 -0.76 1886632.0 -1090000.0 -0.87 -1.1511 -0.9978 3633230 CBKinase1_023382 Cc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccccc4)C(F)(F)F)n(n1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F01 mock treatment 1023873.0 -1920000.0 -1.62 842886.0 -2130000.0 -1.7 -2.3446 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F02 mock treatment 1003151.0 -1940000.0 -1.63 1253515.0 -1720000.0 -1.37 -2.1255 -0.9963 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F03 compound treatment 1250690.0 -1690000.0 -1.42 1237416.0 -1740000.0 -1.39 -1.9869 -0.9999 3633231 CBKinase1_023383 COc1cc(ccc1NC(=O)c2ccccc2OCC(=O)NC(C)(C)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F04 compound treatment 1596997.0 -1340000.0 -1.13 1528052.0 -1450000.0 -1.15 -1.6166 -1.0 3633232 CBKinase1_023384 COc1ccccc1NC(=O)c2c(C)c(C)sc2NC(=O)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F05 compound treatment 1413479.0 -1530000.0 -1.29 1366648.0 -1610000.0 -1.28 -1.817 -1.0 3633233 CBKinase1_023385 Cc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2NCc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F06 compound treatment 2005673.0 -933000.0 -0.79 1535409.0 -1440000.0 -1.15 -1.3687 -0.983 3633234 CBKinase1_023386 CC(=O)Nc1sc(C)c(c1C(=O)NCc2cccnc2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F07 compound treatment 1743268.0 -1200000.0 -1.01 1455842.0 -1520000.0 -1.21 -1.57 -0.9958 3633235 CBKinase1_023387 Clc1cccc(NC(=O)Cn2cnc3scc(c4ccc5ccccc5c4)c3c2=O)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F08 compound treatment 2115476.0 -823000.0 -0.69 1850833.0 -1130000.0 -0.9 -1.1254 -0.992 3633236 CBKinase1_023388 Cc1noc(C)c1C(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F09 mock treatment 2093331.0 -846000.0 -0.71 1881564.0 -1090000.0 -0.87 -1.1213 -0.995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F10 mock treatment 2063714.0 -875000.0 -0.74 1751393.0 -1220000.0 -0.98 -1.2124 -0.9905 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F11 compound treatment 2015176.0 -924000.0 -0.78 1778369.0 -1200000.0 -0.95 -1.2261 -0.9949 3633237 CBKinase1_023389 COc1ccc(NC(=O)CSc2nnc(C)c(=O)[nH]2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F12 compound treatment 2206628.0 -732000.0 -0.62 2254962.0 -721000.0 -0.57 -0.8433 -0.9994 3633238 CBKinase1_023390 [O-][N+](=O)c1ccn(CC(=O)n2cccn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F13 compound treatment 2050487.0 -888000.0 -0.75 1819697.0 -1160000.0 -0.92 -1.1817 -0.9947 3633239 CBKinase1_023391 COc1cccc2cc(C(=O)Nc3sc4CCCCCc4c3C(=O)N)c(=O)oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F14 compound treatment 2242732.0 -696000.0 -0.59 2016627.0 -960000.0 -0.76 -0.9561 -0.9915 3633240 CBKinase1_023392 COc1ccc(cc1OC)c2nnc(SCCC(=O)O)n2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F15 compound treatment 2197016.0 -742000.0 -0.63 1855675.0 -1120000.0 -0.89 -1.0741 -0.9849 3633241 CBKinase1_023393 NC(=O)c1c(NC(=O)COc2cccc(c2)C(F)(F)F)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F16 compound treatment 2421870.0 -517000.0 -0.44 2158031.0 -818000.0 -0.65 -0.7696 -0.9809 3633242 CBKinase1_023394 CC(C(=O)N1CCCc2ccccc12)n3nc([N+](=O)[O-])c(Br)c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F17 mock treatment 2257007.0 -682000.0 -0.58 2235612.0 -741000.0 -0.59 -0.8242 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F18 mock treatment 2090303.0 -849000.0 -0.72 2268099.0 -708000.0 -0.56 -0.9053 -0.9931 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F19 compound treatment 2186733.0 -752000.0 -0.63 2683571.0 -293000.0 -0.23 -0.6136 -0.9077 3633243 CBKinase1_023395 COC(=O)c1c(NC(=O)c2cc3cccc(OC)c3oc2=O)scc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F20 compound treatment 2364567.0 -574000.0 -0.48 2257532.0 -719000.0 -0.57 -0.7477 -0.9965 3633244 CBKinase1_023396 CCOc1ccc(cc1S(=O)(=O)Nc2c(C)cccc2C)n3cnnn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F21 compound treatment 2651355.0 -288000.0 -0.24 1940909.0 -1040000.0 -0.83 -0.755 -0.8778 3633245 CBKinase1_023397 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3csc(C)c3)cc2)nc(OC)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F22 compound treatment 2632359.0 -307000.0 -0.26 2282709.0 -694000.0 -0.55 -0.5737 -0.9401 3633246 CBKinase1_023398 CS(=O)(=O)N(CC(=O)N1CCC(CC1)C(=O)N)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F23 compound treatment 2485598.0 -453000.0 -0.38 2366612.0 -610000.0 -0.49 -0.614 -0.993 3633247 CBKinase1_023399 CN1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)C3CC=CCC3C(=O)O)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 F24 compound treatment 2118814.0 -820000.0 -0.69 1916338.0 -1060000.0 -0.84 -1.0865 -0.9951 3633248 CBKinase1_023400 CC(C)N(Cc1nc(no1)c2ccc(Cl)cc2)S(=O)(=O)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G01 compound treatment 2218913.0 -720000.0 -0.61 2417236.0 -559000.0 -0.45 -0.7445 -0.9884 3633249 CBKinase1_023401 Cc1sc2nc(SCC(=O)c3cccs3)n(Cc4ccco4)c(=O)c2c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G02 compound treatment 3284169.0 345000.0 0.29 2607956.0 -368000.0 -0.29 -0.0017 -0.004 3633250 CBKinase1_023402 COc1ccccc1NC(=O)CSc2nc(C)cc(n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G03 mock treatment 2494139.0 -445000.0 -0.38 2462031.0 -514000.0 -0.41 -0.5551 -0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G04 mock treatment 2741657.0 -197000.0 -0.17 2865458.0 -111000.0 -0.09 -0.1801 -0.9561 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G05 compound treatment 2699346.0 -240000.0 -0.2 2699627.0 -277000.0 -0.22 -0.2988 -0.999 3633251 CBKinase1_023403 CC(=O)c1c(C)cc(C)c(CSc2nnc(o2)c3ccco3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G06 compound treatment 2998036.0 59100.0 0.05 2855950.0 -120000.0 -0.1 -0.0326 -0.3012 1412223 CBKinase1_023404 Cc1ccc(OCC(=O)Nc2ccc(Cl)cc2)c(c1)n3nc4ccccc4n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G07 compound treatment 2894282.0 -44600.0 -0.04 2975980.0 -308.0 0.0 -0.0268 -0.7117 3633252 CBKinase1_023405 Cc1c(NC(=O)CSc2nc3cc(ccc3s2)C(=O)N4CCCC4)c(=O)n(c5ccccc5)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G08 compound treatment 2875409.0 -63500.0 -0.05 2924770.0 -51500.0 -0.04 -0.0669 -0.9914 3633253 CBKinase1_023406 Cc1ccc(NS(=O)(=O)c2cc(ccc2Cl)C(=O)Nc3ccccc3C(=O)N4CCOCC4)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G09 compound treatment 3132565.0 194000.0 0.16 2748889.0 -227000.0 -0.18 -0.0127 -0.0519 3633254 CBKinase1_023407 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)COc3ccccc3C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G10 compound treatment 2775156.0 -164000.0 -0.14 2535294.0 -441000.0 -0.35 -0.3462 -0.9167 3633255 CBKinase1_023408 COc1cc(CO)ccc1Oc2nc(nn2Cc3ccccc3F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G11 compound treatment 2654378.0 -285000.0 -0.24 2678718.0 -298000.0 -0.24 -0.3374 -1.0 3633256 CBKinase1_023409 NC(=O)C1(CCN(CC(=O)Nc2cc(Cl)ccc2Cl)CC1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G12 compound treatment 2813751.0 -125000.0 -0.11 2758147.0 -218000.0 -0.17 -0.1976 -0.9714 3633257 CBKinase1_023410 COc1cccc(NC(=O)CCc2nc(no2)c3ccc(C)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G13 compound treatment 2934965.0 -3950.0 0.0 2693244.0 -283000.0 -0.23 -0.1619 -0.7175 3633258 CBKinase1_023411 CCNC(=O)CCc1nc(no1)c2ccc(OC)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G14 compound treatment 2770949.0 -168000.0 -0.14 2901962.0 -74300.0 -0.06 -0.1421 -0.9252 3633259 CBKinase1_023412 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G15 compound treatment 2889704.0 -49200.0 -0.04 2735712.0 -241000.0 -0.19 -0.1649 -0.8407 3633260 CBKinase1_023413 Cc1[nH]nc2OC(=C(C#N)C(c12)c3cc(CN4CCOCC4)c(C)cc3C)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G16 compound treatment 2795628.0 -143000.0 -0.12 2812529.0 -164000.0 -0.13 -0.1778 -0.9993 3118294 CBKinase1_023414 COc1ccc2[nH]c(SCc3cnc(C)nc3N)nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G17 compound treatment 3228291.0 289000.0 0.24 2842579.0 -134000.0 -0.11 0.0972 0.3651 3633261 CBKinase1_023415 Cc1ccc(cc1)c2cc(no2)C(=O)NCCCn3ccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G18 compound treatment 3157164.0 218000.0 0.18 2828741.0 -148000.0 -0.12 0.047 0.2152 3633262 CBKinase1_023416 Cc1ccc(cc1)c2cc(no2)C(=O)NCCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G19 mock treatment 3544691.0 606000.0 0.51 3064601.0 88300.0 0.07 0.4111 0.797 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G20 mock treatment 2466827.0 -472000.0 -0.4 2385091.0 -591000.0 -0.47 -0.6148 -0.9965 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G21 compound treatment 3301631.0 363000.0 0.31 2758842.0 -217000.0 -0.17 0.0938 0.2667 3633263 CBKinase1_023417 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3c(C)nn(Cc4ccc(F)cc4)c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G22 compound treatment 3026667.0 87800.0 0.07 3089139.0 113000.0 0.09 0.1159 0.9953 3633264 CBKinase1_023418 Cc1c(Cl)cccc1NC(=O)CSCC(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G23 compound treatment 2860988.0 -77900.0 -0.07 2798393.0 -178000.0 -0.14 -0.1467 -0.9389 1986395 CBKinase1_023419 O=C(NCc1ccco1)c2n[nH]c(=O)c3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 G24 compound treatment 2775669.0 -163000.0 -0.14 2488058.0 -488000.0 -0.39 -0.3725 -0.9025 3633265 CBKinase1_023420 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCc3cccnc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H01 compound treatment 2129770.0 -809000.0 -0.68 2193550.0 -783000.0 -0.62 -0.9238 -0.999 3633266 CBKinase1_023421 COc1ccc(C(=O)c2ccccc2)c(Oc3nc(nn3C)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H02 compound treatment 2742247.0 -197000.0 -0.17 3012913.0 36600.0 0.03 -0.0967 -0.5739 3633267 CBKinase1_023422 O=C(NCc1ccco1)c2ccsc2NC(=O)c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H03 mock treatment 2766938.0 -172000.0 -0.15 2874747.0 -102000.0 -0.08 -0.1598 -0.962 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H04 mock treatment 3110056.0 171000.0 0.14 3281787.0 305000.0 0.24 0.2743 0.9689 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H05 compound treatment 3263278.0 324000.0 0.27 2965581.0 -10700.0 -0.01 0.1874 0.6847 3633268 CBKinase1_023423 Cc1cc(C)c(C#N)c(NCCCN2CCOCC2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H06 compound treatment 3336229.0 397000.0 0.34 2993637.0 17300.0 0.01 0.2468 0.7357 3633269 CBKinase1_023424 Fc1cccc2sc(C(=O)NCCCn3ccnc3)c(Cl)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H07 compound treatment 3264690.0 326000.0 0.27 2813472.0 -163000.0 -0.13 0.1025 0.3374 3633270 CBKinase1_023425 COC(=O)c1cc(C)sc1NC(=O)CC2Nc3ccccc3NC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H08 compound treatment 2879910.0 -59000.0 -0.05 2917173.0 -59100.0 -0.05 -0.0685 -0.9996 3633271 CBKinase1_023426 Cc1onc(c1C(=O)NCCc2ccc(cc2)S(=O)(=O)N)c3c(F)cccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H09 compound treatment 3163769.0 225000.0 0.19 3148832.0 173000.0 0.14 0.2314 0.9875 1748461 CBKinase1_023427 CCOC(=O)c1cnc(SCC(=O)N2CCc3ccccc23)nc1N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H10 compound treatment 3266969.0 328000.0 0.28 3202978.0 227000.0 0.18 0.3234 0.9787 3633272 CBKinase1_023428 CCOc1ccc(NC(=O)Cn2cc(cn2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H11 compound treatment 3200926.0 262000.0 0.22 2987858.0 11600.0 0.01 0.1628 0.736 3633273 CBKinase1_023429 COc1cccc(NC(=O)Cn2cc(C(=O)C(C)(C)C)c3ccccc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H12 compound treatment 3086220.0 147000.0 0.12 3119249.0 143000.0 0.11 0.1684 0.9991 3633274 CBKinase1_023430 CCN(CC(=O)Nc1cccc(c1)C(=O)C)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H13 compound treatment 2986544.0 47600.0 0.04 2749679.0 -227000.0 -0.18 -0.0993 -0.5367 3633275 CBKinase1_023431 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3ccc(Oc4ccc(Cl)cc4)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H14 compound treatment 3040903.0 102000.0 0.09 2994405.0 18100.0 0.01 0.071 0.8144 3633276 CBKinase1_023432 COc1ccc(NC(=O)COc2c(Cl)c(C)c(Cl)c(C)c2Cl)cc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H15 compound treatment 3009663.0 70800.0 0.06 3026822.0 50500.0 0.04 0.0707 0.9817 3633277 CBKinase1_023433 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2c(C)onc2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H16 compound treatment 3084749.0 146000.0 0.12 3125706.0 149000.0 0.12 0.1712 0.9999 3633278 CBKinase1_023434 CC1(C)CC(=O)c2c(O)cc(OCC(=O)c3ccccc3)cc2O1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H17 compound treatment 3041338.0 102000.0 0.09 3397704.0 421000.0 0.34 0.2986 0.861 3633279 CBKinase1_023435 COc1ccccc1C(=O)NCCCN2CCCC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H18 compound treatment 2750791.0 -188000.0 -0.16 2869977.0 -106000.0 -0.08 -0.1721 -0.9568 3633280 CBKinase1_023436 COc1ccccc1C(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4cccnc4)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H19 mock treatment 3525152.0 586000.0 0.49 3460724.0 484000.0 0.39 0.6227 0.9925 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H20 mock treatment 2531841.0 -407000.0 -0.34 3526600.0 550000.0 0.44 0.0674 0.1209 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H21 compound treatment 3592640.0 654000.0 0.55 3547455.0 571000.0 0.46 0.7118 0.9955 3633281 CBKinase1_023437 Cc1ccc(Cl)c(OCC(=O)NCc2cccnc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H22 compound treatment 3508605.0 570000.0 0.48 3396360.0 420000.0 0.33 0.5765 0.9844 3633282 CBKinase1_023438 Brc1ccc(o1)C(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H23 compound treatment 2503582.0 -435000.0 -0.37 3148012.0 172000.0 0.14 -0.1629 -0.4156 3633283 CBKinase1_023439 COc1ccccc1NC(=O)c2c(C)c(C)sc2NC(=O)c3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 H24 compound treatment 2936594.0 -2320.0 0.0 2761836.0 -214000.0 -0.17 -0.1222 -0.7151 3633284 CBKinase1_023440 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I01 compound treatment 2385147.0 -554000.0 -0.47 2286175.0 -690000.0 -0.55 -0.7192 -0.9967 3633285 CBKinase1_023441 O=C(CSc1nnc(c2cccnc2)n1c3ccccc3)N4CCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I02 compound treatment 2638585.0 -300000.0 -0.25 2933344.0 -42900.0 -0.03 -0.2033 -0.7954 3633286 CBKinase1_023442 Cc1cc2c(=O)n(Cc3ccco3)c(SCc4cc(O)[nH]n4)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I03 compound treatment 3078758.0 140000.0 0.12 2789154.0 -187000.0 -0.15 -0.0221 -0.116 3633287 CBKinase1_023443 COc1ccccc1OCCCn2cc(C(=O)C(C)(C)C)c3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I04 compound treatment 2843971.0 -94900.0 -0.08 2737015.0 -239000.0 -0.19 -0.1915 -0.9257 3633288 CBKinase1_023444 CC(=O)c1cccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I05 mock treatment 3103905.0 165000.0 0.14 3002959.0 26700.0 0.02 0.1134 0.8058 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I06 mock treatment 3111772.0 173000.0 0.15 3037210.0 60900.0 0.05 0.1374 0.8943 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I07 compound treatment 3153050.0 214000.0 0.18 2783720.0 -193000.0 -0.15 0.0192 0.081 3633289 CBKinase1_023445 Cc1nnc(SCC(=O)Nc2ccccc2C#N)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I08 compound treatment 3133822.0 195000.0 0.16 3070970.0 94700.0 0.08 0.1696 0.9376 3633290 CBKinase1_023446 CCC(N1C(=O)c2ccccc2C1=O)c3nc4ccccc4c(=O)n3c5cccnc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I09 compound treatment 3092197.0 153000.0 0.13 2398124.0 -578000.0 -0.46 -0.2344 -0.4898 3633291 CBKinase1_023447 COC(=O)c1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4cc(OC)c(Cl)cc4OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I10 compound treatment 3132165.0 193000.0 0.16 2762582.0 -214000.0 -0.17 -0.0052 -0.022 3633292 CBKinase1_023448 COc1ccc(cc1)c2nc3ccccc3c(=O)n2CCCN4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I11 compound treatment 3018644.0 79700.0 0.07 2872172.0 -104000.0 -0.08 -0.0111 -0.1041 3633293 CBKinase1_023449 Cc1cc(C)cc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I12 compound treatment 2844715.0 -94200.0 -0.08 2766597.0 -210000.0 -0.17 -0.1744 -0.9422 3633294 CBKinase1_023450 CCOc1ccccc1NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I13 compound treatment 2877097.0 -61800.0 -0.05 3076678.0 100000.0 0.08 0.0197 0.2064 3633295 CBKinase1_023451 COc1ccc(cc1)C(=O)CSc2nnc(c3cc4ccccc4o3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I14 compound treatment 3154026.0 215000.0 0.18 2849709.0 -127000.0 -0.1 0.057 0.2744 3633296 CBKinase1_023452 COC(=O)c1ccc(NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I15 compound treatment 2942951.0 4040.0 0.0 2995204.0 18900.0 0.02 0.0131 0.8456 3633297 CBKinase1_023453 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCc3ccccn3)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I16 compound treatment 2949340.0 10400.0 0.01 3059874.0 83600.0 0.07 0.0533 0.7936 3633298 CBKinase1_023454 Cc1c(Cl)cccc1NC(=O)COc2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I17 compound treatment 3172686.0 234000.0 0.2 2963192.0 -13100.0 -0.01 0.1321 0.6687 3633299 CBKinase1_023455 Cn1c(SCC(=O)c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)nnc1c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I18 compound treatment 2987264.0 48400.0 0.04 2871790.0 -104000.0 -0.08 -0.0301 -0.3241 3633300 CBKinase1_023456 COc1ccc2[nH]c(SCC(=O)N3CCCc4ccccc34)nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I19 compound treatment 3610457.0 672000.0 0.57 3673078.0 697000.0 0.56 0.7932 1.0 3633301 CBKinase1_023457 Brc1ccc2oc(=O)c(cc2c1)C(=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I20 compound treatment 3235445.0 297000.0 0.25 3394902.0 419000.0 0.33 0.4128 0.9899 3633302 CBKinase1_023458 CCOC(=O)C1=C(Cn2ccc(n2)C(F)(F)F)NC(=O)NC1c3cc(C)ccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I21 mock treatment 3132517.0 194000.0 0.16 3236784.0 260000.0 0.21 0.2623 0.9929 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I22 mock treatment 3429280.0 490000.0 0.41 2988821.0 12500.0 0.01 0.2995 0.724 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I23 compound treatment 3283654.0 345000.0 0.29 2964569.0 -11700.0 -0.01 0.199 0.684 3633303 CBKinase1_023459 NC(=O)C1(CCN(CC(=O)Nc2ccc(F)c(Cl)c2)CC1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 I24 compound treatment 2973170.0 34300.0 0.03 2491028.0 -485000.0 -0.39 -0.2531 -0.6525 3085966 CBKinase1_023460 OCc1ccccc1NC(=S)Nc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J01 compound treatment 2316501.0 -622000.0 -0.53 2435536.0 -541000.0 -0.43 -0.676 -0.9952 3633304 CBKinase1_023461 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccc(cc2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J02 compound treatment 2591746.0 -347000.0 -0.29 2823582.0 -153000.0 -0.12 -0.2931 -0.9243 3633305 CBKinase1_023462 Fc1cccc(F)c1C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J03 compound treatment 2757084.0 -182000.0 -0.15 2872270.0 -104000.0 -0.08 -0.1671 -0.9583 3633306 CBKinase1_023463 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J04 compound treatment 2677486.0 -261000.0 -0.22 3386340.0 410000.0 0.33 0.0752 0.1907 3633307 CBKinase1_023464 COC(=O)Nc1sc(C)c(C)c1C(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J05 mock treatment 3067568.0 129000.0 0.11 3464497.0 488000.0 0.39 0.3519 0.8711 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J06 mock treatment 3235828.0 297000.0 0.25 3512657.0 536000.0 0.43 0.4794 0.9675 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J07 compound treatment 3076913.0 138000.0 0.12 3304342.0 328000.0 0.26 0.2672 0.9336 3633308 CBKinase1_023465 CN(c1cccc(NC(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)c1)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J08 compound treatment 2947846.0 8930.0 0.01 3205490.0 229000.0 0.18 0.1345 0.7357 3633309 CBKinase1_023466 Cc1cc(C)n(n1)c2nc3ccccc3nc2N4CCN(CC4)S(=O)(=O)c5ccc(C)cc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J09 compound treatment 2953244.0 14300.0 0.01 3481892.0 506000.0 0.4 0.2935 0.728 3633310 CBKinase1_023467 Cc1ccc(NC(=O)CSc2nc(C)cc(n2)c3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J10 compound treatment 3049229.0 110000.0 0.09 3329427.0 353000.0 0.28 0.2648 0.8933 3123074 CBKinase1_023468 Cc1nnc(SCCCC(=O)c2ccc(cc2)C(C)(C)C)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J11 compound treatment 2986029.0 47100.0 0.04 3399605.0 423000.0 0.34 0.2667 0.785 3633311 CBKinase1_023469 Cc1ccccc1Cn2cc(NC(=O)C3CC(=NO3)c4ccc(Cl)cc4)cn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J12 compound treatment 3025143.0 86200.0 0.07 3334911.0 359000.0 0.29 0.2536 0.8596 3633312 CBKinase1_023470 Nc1nc(SCC(=O)Nc2ccccc2F)ncc1C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J13 compound treatment 2808987.0 -130000.0 -0.11 3383416.0 407000.0 0.32 0.152 0.4437 3633313 CBKinase1_023471 Cc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c(C)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J14 compound treatment 3196532.0 258000.0 0.22 3058031.0 81700.0 0.07 0.1997 0.8804 3633314 CBKinase1_023472 Cc1nn(CC(=O)Nc2cccc(c2)C(F)(F)F)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J15 compound treatment 2931975.0 -6940.0 -0.01 3540918.0 565000.0 0.45 0.3141 0.6979 1878573 CBKinase1_023473 Cc1ccc(Cl)c(OCC(=O)NCc2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J16 compound treatment 3358472.0 420000.0 0.35 3284824.0 309000.0 0.25 0.4241 0.9842 3633315 CBKinase1_023474 CC1(C)CC(=O)c2c(O)cc(OCC(=O)c3ccc(Cl)c(Cl)c3)cc2O1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J17 compound treatment 3241442.0 303000.0 0.26 3143238.0 167000.0 0.13 0.2745 0.9539 3633316 CBKinase1_023475 Cc1occc1C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J18 compound treatment 3180197.0 241000.0 0.2 3351407.0 375000.0 0.3 0.3553 0.9824 3633317 CBKinase1_023476 Cn1c(SCC(=O)c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)nnc1c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J19 compound treatment 3684707.0 746000.0 0.63 3544863.0 569000.0 0.45 0.7653 0.987 3633318 CBKinase1_023477 FC(F)(F)c1cccc(OCC(=O)NCc2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J20 compound treatment 3653425.0 715000.0 0.6 3313340.0 337000.0 0.27 0.6161 0.9337 3633319 CBKinase1_023478 Cc1cnc(SCc2cnc(C)nc2N)nc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J21 mock treatment 3501852.0 563000.0 0.47 3200537.0 224000.0 0.18 0.4621 0.9109 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J22 mock treatment 3162145.0 223000.0 0.19 3417140.0 441000.0 0.35 0.3816 0.9572 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J23 compound treatment 3160588.0 222000.0 0.19 3048495.0 72200.0 0.06 0.1729 0.8838 3633320 CBKinase1_023479 CCOc1ccc2ccccc2c1C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 J24 compound treatment 2854730.0 -84200.0 -0.07 2698792.0 -277000.0 -0.22 -0.2066 -0.8894 3633321 CBKinase1_023480 CCOC(=O)c1cc(C)sc1NC(=O)CC2Sc3ccccc3NC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K01 compound treatment 1239761.0 -1700000.0 -1.43 1244540.0 -1730000.0 -1.38 -1.9895 -0.9998 3633322 CBKinase1_023481 Cc1c(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K02 compound treatment 2151399.0 -788000.0 -0.66 2620123.0 -356000.0 -0.28 -0.6704 -0.9281 3633323 CBKinase1_023482 Cc1nc(SCC(=O)c2ccccc2)c3sc4nc5CC(C)(C)OCc5cc4c3n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K03 compound treatment 2868490.0 -70400.0 -0.06 3179060.0 203000.0 0.16 0.0723 0.4198 3633324 CBKinase1_023483 FC(F)(Cl)c1cc(nc2cc(nn12)C(=O)NCc3cccnc3)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K04 compound treatment 2966288.0 27400.0 0.02 2932005.0 -44300.0 -0.04 -0.0086 -0.2046 3633325 CBKinase1_023484 Cc1ccc(NC(=O)Cn2ccc(n2)[N+](=O)[O-])cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K05 compound treatment 2599535.0 -339000.0 -0.29 2958897.0 -17400.0 -0.01 -0.2122 -0.7405 3633326 CBKinase1_023485 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K06 compound treatment 2889922.0 -49000.0 -0.04 2884303.0 -92000.0 -0.07 -0.0811 -0.9632 3633327 CBKinase1_023486 CSc1ccccc1C(=O)Nc2ccccc2C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K07 mock treatment 2717564.0 -221000.0 -0.19 2940337.0 -36000.0 -0.03 -0.1523 -0.8062 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K08 mock treatment 2708119.0 -231000.0 -0.19 2309390.0 -667000.0 -0.53 -0.5135 -0.9072 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K09 compound treatment 2644905.0 -294000.0 -0.25 2525504.0 -451000.0 -0.36 -0.4294 -0.9836 3633328 CBKinase1_023487 COc1ccc2n(C)c(C)c(/C=C/c3nc4ccc(I)cc4c(=O)n3CCCO)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K10 compound treatment 2747932.0 -191000.0 -0.16 2749715.0 -227000.0 -0.18 -0.2416 -0.9984 3633330 CBKinase1_023488 COc1ccc(NC(=O)CCc2nc(no2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K11 compound treatment 2816751.0 -122000.0 -0.1 2902577.0 -73700.0 -0.06 -0.1144 -0.9645 3633331 CBKinase1_023489 CN1CCN(CC1)c2ccccc2NC(=O)COc3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K12 compound treatment 2962132.0 23200.0 0.02 2762141.0 -214000.0 -0.17 -0.1068 -0.6219 3633332 CBKinase1_023490 COc1ccccc1NC(=O)CCc2nc(no2)c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K13 compound treatment 2588131.0 -351000.0 -0.3 2539170.0 -437000.0 -0.35 -0.4556 -0.9967 3633333 CBKinase1_023491 COc1cc(Br)c(cc1OC)S(=O)(=O)NCCOc2ccc(cc2)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K14 compound treatment 2656159.0 -283000.0 -0.24 2669723.0 -307000.0 -0.24 -0.3414 -0.9999 1987102 CBKinase1_023492 Fc1ccccc1c2noc(CCC(=O)NC3CCCCC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K15 mock treatment 2702980.0 -236000.0 -0.2 2826506.0 -150000.0 -0.12 -0.2251 -0.9701 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K16 mock treatment 2893199.0 -45700.0 -0.04 2958066.0 -18200.0 -0.01 -0.0375 -0.911 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K17 compound treatment 3376451.0 438000.0 0.37 2503622.0 -473000.0 -0.38 -0.0054 -0.0103 3633334 CBKinase1_023493 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)NCCO 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K18 compound treatment 3189818.0 251000.0 0.21 2574660.0 -402000.0 -0.32 -0.0767 -0.1999 3633335 CBKinase1_023494 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)[N+](=O)[O-])c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K19 compound treatment 1812327.0 -1130000.0 -0.95 2518426.0 -458000.0 -0.36 -0.93 -0.9136 3633336 CBKinase1_023495 COc1cc(NC(=O)Cc2cccc3ccccc23)c(cc1OC)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K20 compound treatment 2741188.0 -198000.0 -0.17 2527986.0 -448000.0 -0.36 -0.3706 -0.9398 1986408 CBKinase1_023496 Cc1ncsc1CCSc2nc3ccccc3c(=O)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K21 compound treatment 3649194.0 710000.0 0.6 1698682.0 -1280000.0 -1.02 -0.2964 -0.2509 3633337 CBKinase1_023497 CN(C)c1nc(N)nc(CSc2nnnn2c3ccccc3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K22 compound treatment 3144999.0 206000.0 0.17 2012408.0 -964000.0 -0.77 -0.4203 -0.5336 3633338 CBKinase1_023498 Cc1ncsc1CCSc2nc3ccccc3c(=O)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K23 mock treatment 3331713.0 393000.0 0.33 2123432.0 -853000.0 -0.68 -0.2464 -0.3258 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 K24 mock treatment 2870474.0 -68400.0 -0.06 2709842.0 -266000.0 -0.21 -0.191 -0.8678 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L01 compound treatment 2551125.0 -388000.0 -0.33 2874950.0 -101000.0 -0.08 -0.2884 -0.856 3633339 CBKinase1_023499 Cc1cccc(C)c1NC(=O)COc2ccc3cc(c4ccccc4)c(=O)oc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L02 compound treatment 2869248.0 -69700.0 -0.06 2963339.0 -12900.0 -0.01 -0.0488 -0.8188 3633340 CBKinase1_023500 COc1cccc(NC(=O)c2c(NC(=O)c3cccnc3)sc4CCCc24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L03 compound treatment 2700711.0 -238000.0 -0.2 2383985.0 -592000.0 -0.47 -0.4759 -0.9275 3633341 CBKinase1_023501 Cc1cc(ccc1Br)N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L04 compound treatment 2785049.0 -154000.0 -0.13 2798349.0 -178000.0 -0.14 -0.1921 -0.999 1172135 CBKinase1_023502 CCOc1cccc2cc(C(=O)NCc3ccco3)c(=O)oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L05 compound treatment 2773425.0 -165000.0 -0.14 3091551.0 115000.0 0.09 -0.0337 -0.2019 3633342 CBKinase1_023503 C(c1nnc2sc(nn12)c3cccnc3)n4cnc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L06 compound treatment 2920151.0 -18800.0 -0.02 3082014.0 106000.0 0.08 0.0484 0.5645 3633343 CBKinase1_023504 O=C(COc1ccccc1)Nc2scc3c2c(=O)oc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L07 mock treatment 3094266.0 155000.0 0.13 2846122.0 -130000.0 -0.1 0.0193 0.1155 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L08 mock treatment 3091311.0 152000.0 0.13 3096453.0 120000.0 0.1 0.1586 0.9895 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L09 compound treatment 3270222.0 331000.0 0.28 2984543.0 8250.0 0.01 0.2023 0.7236 3633344 CBKinase1_023505 CS(=O)CCC(NS(=O)(=O)c1ccccc1)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L10 compound treatment 2803204.0 -136000.0 -0.11 2862535.0 -114000.0 -0.09 -0.1451 -0.9933 3633345 CBKinase1_023506 COC(=O)CCC(=O)NC(=S)Nc1cc(Cl)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L11 compound treatment 3035956.0 97000.0 0.08 3011860.0 35600.0 0.03 0.0779 0.8996 3633346 CBKinase1_023507 CCOC(=O)c1cc(OC(=O)c2ccccc2[N+](=O)[O-])n(n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L12 compound treatment 3121750.0 183000.0 0.15 3008812.0 32500.0 0.03 0.1274 0.8145 3633347 CBKinase1_023508 COc1ccc2C(=CC(C)(C)N(C(=O)CSc3nnc(C)[nH]3)c2c1)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L13 compound treatment 3121871.0 183000.0 0.15 2982306.0 6020.0 0.0 0.1125 0.7287 3633348 CBKinase1_023509 O=C(NCc1ccco1)c2c(NC(=O)c3ccccc3)scc2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L14 compound treatment 3192138.0 253000.0 0.21 3131287.0 155000.0 0.12 0.2384 0.9661 3633349 CBKinase1_023510 Clc1ccc(c2nnc(SCC(=O)Nc3cccc(Cl)c3Cl)[nH]2)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L15 mock treatment 3090981.0 152000.0 0.13 2809661.0 -167000.0 -0.13 -0.0032 -0.0174 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L16 mock treatment 3557310.0 618000.0 0.52 3370188.0 394000.0 0.31 0.5908 0.9705 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L17 compound treatment 3164333.0 225000.0 0.19 3105818.0 130000.0 0.1 0.2075 0.9588 3633350 CBKinase1_023511 NS(=O)(=O)c1ccc(CCNC(=O)c2cccnc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L18 compound treatment 3706126.0 767000.0 0.65 3405286.0 429000.0 0.34 0.6994 0.9555 3633351 CBKinase1_023512 NC(=O)CS(=O)(=O)c1nc2ccccc2n1CC(=O)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L19 compound treatment 4092659.0 1150000.0 0.97 1811015.0 -1170000.0 -0.93 0.0314 0.0233 3633352 CBKinase1_023513 COc1ccccc1NC(=O)c2c(C)c(C)sc2NC(=O)Cc3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L20 compound treatment 4194082.0 1260000.0 1.06 3882335.0 906000.0 0.72 1.2593 0.9826 3633353 CBKinase1_023514 COc1ccc(cc1)c2cc(nc(SCC(=O)Nc3ccccc3C)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L21 compound treatment 4085956.0 1150000.0 0.97 2254757.0 -722000.0 -0.58 0.2775 0.2465 3633354 CBKinase1_023515 COc1ccc(OC)c(NC(=O)c2c(NC(=O)c3ccco3)sc4CCCc24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L22 compound treatment 3590922.0 652000.0 0.55 3090809.0 115000.0 0.09 0.4534 0.8133 3633355 CBKinase1_023516 COc1cc2[nH]c(=S)n(CCCN3CCOCC3)c(=O)c2cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L23 mock treatment 3379645.0 441000.0 0.37 3429229.0 453000.0 0.36 0.5181 0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 L24 mock treatment 2823228.0 -116000.0 -0.1 2931133.0 -45200.0 -0.04 -0.0944 -0.9081 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M01 compound treatment 1293077.0 -1650000.0 -1.39 2176249.0 -800000.0 -0.64 -1.4325 -0.9377 3633356 CBKinase1_023517 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M02 compound treatment 2273648.0 -665000.0 -0.56 2729537.0 -247000.0 -0.2 -0.5359 -0.9012 3633357 CBKinase1_023518 Cc1cc(C)n(n1)c2nc3ccc(cc3nc2n4nc(C)cc4C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M03 compound treatment 2809432.0 -129000.0 -0.11 2481100.0 -495000.0 -0.39 -0.3563 -0.8701 1192959 CBKinase1_023519 OCCCn1c(=O)[nH]c2ccccc2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M04 compound treatment 3114733.0 176000.0 0.15 3191953.0 216000.0 0.17 0.2264 0.9973 3633358 CBKinase1_023520 COC(=O)c1c(C)n(CCCOC(C)C)c2c1cc(O)c3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M05 compound treatment 2404939.0 -534000.0 -0.45 3406062.0 430000.0 0.34 -0.0763 -0.1348 3633359 CBKinase1_023521 Cc1ccc(cc1)c2cc(no2)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M06 compound treatment 2969491.0 30600.0 0.03 3307728.0 331000.0 0.26 0.205 0.7725 3633360 CBKinase1_023522 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nc(C)cc(n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M07 compound treatment 2650196.0 -289000.0 -0.24 3010415.0 34100.0 0.03 -0.153 -0.6242 3633361 CBKinase1_023523 Cc1cc(ccc1Br)N(CC(=O)Nc2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M08 compound treatment 2709446.0 -229000.0 -0.19 3433954.0 458000.0 0.36 0.1211 0.2932 3633362 CBKinase1_023524 Oc1cc(CSc2nc3sc4CCCc4c3c(=O)n2Cc5ccco5)n[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M09 mock treatment 2953627.0 14700.0 0.01 3455796.0 480000.0 0.38 0.279 0.7297 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M10 mock treatment 2727207.0 -212000.0 -0.18 3458943.0 483000.0 0.38 0.1458 0.3437 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M11 compound treatment 2820908.0 -118000.0 -0.1 3411281.0 435000.0 0.35 0.1748 0.4845 3633363 CBKinase1_023525 Oc1cc(OCC(=O)c2ccc(Br)cc2)cc3oc4ccccc4c(=O)c13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M12 compound treatment 2668929.0 -270000.0 -0.23 3565016.0 589000.0 0.47 0.1708 0.3274 3042714 CBKinase1_023526 C(c1nn2c(Cn3cnc4ccccc34)nnc2s1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M13 mock treatment 2630980.0 -308000.0 -0.26 3314255.0 338000.0 0.27 0.0068 0.0182 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M14 mock treatment 3102541.0 164000.0 0.14 3680674.0 704000.0 0.56 0.4946 0.8555 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M15 compound treatment 2758263.0 -181000.0 -0.15 3298401.0 322000.0 0.26 0.0738 0.2472 3633364 CBKinase1_023527 NC(=O)CSc1oc(nc1S(=O)(=O)c2ccccc2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M16 compound treatment 2895134.0 -43800.0 -0.04 3433604.0 457000.0 0.36 0.2316 0.6322 3633365 CBKinase1_023528 Ic1cccc(NC(=O)CSc2nnnn2c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M17 compound treatment 3301650.0 363000.0 0.31 3018715.0 42400.0 0.03 0.2403 0.7805 3633366 CBKinase1_023529 COc1ccc(cc1Cl)S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M18 compound treatment 3175632.0 237000.0 0.2 3473554.0 497000.0 0.4 0.4214 0.9496 3633367 CBKinase1_023530 Cc1cc(=O)n2c3ccccc3n(CC(O)Cn4ccnc4)c2c1C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M19 compound treatment 2817764.0 -121000.0 -0.1 3293297.0 317000.0 0.25 0.1064 0.3904 3633368 CBKinase1_023531 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3ccc(F)c(Cl)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M20 compound treatment 3768484.0 830000.0 0.7 2480796.0 -495000.0 -0.39 0.2155 0.2682 3633369 CBKinase1_023532 NC(=O)CSc1oc(nc1S(=O)(=O)c2ccccc2)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M21 compound treatment 965570.0 -1970000.0 -1.66 1348957.0 -1630000.0 -1.3 -2.0941 -0.9924 3633370 CBKinase1_023533 [O-][N+](=O)c1nn(c2ccccc2)[n+]([O-])c1NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M22 compound treatment 3271636.0 333000.0 0.28 2220234.0 -756000.0 -0.6 -0.2277 -0.3425 3633371 CBKinase1_023534 CCOC(=O)CNc1nc2ccccc2n3cnnc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M23 compound treatment 3163910.0 225000.0 0.19 3483447.0 507000.0 0.4 0.42 0.9406 3633372 CBKinase1_023535 COc1ccc(cc1OC)S(=O)(=O)NCCOc2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 M24 compound treatment 2834653.0 -104000.0 -0.09 3225899.0 250000.0 0.2 0.0785 0.3609 3088269 CBKinase1_023536 CC1CCc2c(C1)sc3nc(SCc4nc(no4)c5ccccc5)n(C)c(=O)c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N01 compound treatment 2569435.0 -369000.0 -0.31 2652539.0 -324000.0 -0.26 -0.4028 -0.9956 3633373 CBKinase1_023537 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)CSc3ccc(Cl)cc3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N02 compound treatment 2480702.0 -458000.0 -0.39 2874441.0 -102000.0 -0.08 -0.3307 -0.8374 3633374 CBKinase1_023538 OC(=O)C1CC=CCC1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N03 compound treatment 2453891.0 -485000.0 -0.41 3614352.0 638000.0 0.51 0.0703 0.1077 3633375 CBKinase1_023539 Clc1ccc(NC(=O)Nc2ccccc2C(=O)NCc3ccco3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N04 compound treatment 2825032.0 -114000.0 -0.1 3614661.0 638000.0 0.51 0.2919 0.5637 3633376 CBKinase1_023540 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4CCCCc4s3)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N05 compound treatment 2801207.0 -138000.0 -0.12 3283140.0 307000.0 0.24 0.0908 0.3354 3633377 CBKinase1_023541 Clc1ccc(cc1)c2noc(CCC(=O)Nc3cccnc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N06 compound treatment 3045194.0 106000.0 0.09 3691964.0 716000.0 0.57 0.4667 0.8083 3633378 CBKinase1_023542 COc1ccccc1NC(=O)c2c(C)c(C)sc2NC(=O)COc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N07 compound treatment 2914750.0 -24200.0 -0.02 3268723.0 292000.0 0.23 0.1504 0.6428 1221192 CBKinase1_023543 O=C(CSc1nc2ccccc2s1)c3cc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N08 compound treatment 3032482.0 93600.0 0.08 3831498.0 855000.0 0.68 0.5378 0.7837 3633379 CBKinase1_023544 CCOc1ccccc1c2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N09 mock treatment 2414242.0 -525000.0 -0.44 3413490.0 437000.0 0.35 -0.0665 -0.1181 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N10 mock treatment 2885181.0 -53700.0 -0.05 3316580.0 340000.0 0.27 0.1597 0.5809 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N11 compound treatment 2437000.0 -502000.0 -0.42 3333865.0 358000.0 0.29 -0.0978 -0.1917 3633380 CBKinase1_023545 Clc1ccc2nc(SCc3csc(Nc4ccccc4)n3)oc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N12 compound treatment 2745459.0 -193000.0 -0.16 3548432.0 572000.0 0.46 0.2071 0.4275 3633381 CBKinase1_023546 O=C(CN1CCCC1)Nc2sc3CCCCc3c2C(=O)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N13 mock treatment 2705025.0 -234000.0 -0.2 3454300.0 478000.0 0.38 0.1299 0.3028 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N14 mock treatment 2954983.0 16100.0 0.01 3345086.0 369000.0 0.29 0.2174 0.7389 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N15 compound treatment 3042373.0 103000.0 0.09 3164475.0 188000.0 0.15 0.1678 0.9668 3633382 CBKinase1_023547 CCOC(=O)c1sc(NC(=O)c2cc(C)on2)c(C(=O)OCC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N16 compound treatment 2862497.0 -76400.0 -0.06 3709048.0 733000.0 0.58 0.3674 0.6253 3633383 CBKinase1_023548 CC1(C)CC(=O)c2c(O)cc(OCC(=O)c3cccc(c3)[N+](=O)[O-])cc2O1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N17 compound treatment 3087351.0 148000.0 0.13 3529308.0 553000.0 0.44 0.4002 0.8734 3633384 CBKinase1_023549 COC(=O)c1sccc1NC(=O)COc2cc(C)ccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N18 compound treatment 2964979.0 26100.0 0.02 3595341.0 619000.0 0.49 0.3644 0.7379 3633385 CBKinase1_023550 COc1ccc(CCNC(=O)c2cc(on2)c3ccccc3)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N19 compound treatment 3880202.0 941000.0 0.79 2424088.0 -552000.0 -0.44 0.2502 0.2756 3633386 CBKinase1_023551 COC(=O)Nc1scc(c1C(=O)NCc2ccco2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N20 compound treatment 2610342.0 -329000.0 -0.28 2955224.0 -21100.0 -0.02 -0.2078 -0.7486 3633387 CBKinase1_023552 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)NCC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N21 compound treatment 3278563.0 340000.0 0.29 2995818.0 19500.0 0.02 0.2136 0.7444 3633388 CBKinase1_023553 Cc1cc(no1)C(=O)NCCCN2CCCC2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N22 compound treatment 3460061.0 521000.0 0.44 3584282.0 608000.0 0.48 0.6535 0.9988 3633389 CBKinase1_023554 NC(=O)COc1ccc(cc1)S(=O)(=O)N2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N23 compound treatment 3051619.0 113000.0 0.1 3418663.0 442000.0 0.35 0.3165 0.8668 1457693 CBKinase1_023555 Cc1noc(C)c1C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 N24 compound treatment 2788260.0 -151000.0 -0.13 2558058.0 -418000.0 -0.33 -0.3256 -0.9126 3633390 CBKinase1_023556 COC(=O)c1ccccc1NC(=O)C2CCCN(C2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O01 compound treatment 3160598.0 222000.0 0.19 2755505.0 -221000.0 -0.18 0.0078 0.0303 3633391 CBKinase1_023557 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O02 compound treatment 2424400.0 -515000.0 -0.43 3742655.0 766000.0 0.61 0.125 0.1669 3633392 CBKinase1_023558 Cn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4cc5ccccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O03 compound treatment 2283605.0 -655000.0 -0.55 2937103.0 -39200.0 -0.03 -0.4129 -0.7459 3633393 CBKinase1_023559 Clc1cc(Cl)c(OCC(=O)Nc2ccccc2C(=O)N3CCCCC3)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O04 compound treatment 3361882.0 423000.0 0.36 3549540.0 573000.0 0.46 0.5754 0.9925 3633394 CBKinase1_023560 CCOC(=O)c1cccc(NC(=O)COc2ccc(Br)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O05 compound treatment 3782333.0 843000.0 0.71 3856861.0 881000.0 0.7 0.9993 1.0 3633395 CBKinase1_023561 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5cnccn5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O06 compound treatment 3046452.0 108000.0 0.09 3588246.0 612000.0 0.49 0.409 0.8245 3633396 CBKinase1_023562 O=c1[nH]c(CSc2nnc(o2)c3ccccc3)nc4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O07 compound treatment 2849094.0 -89800.0 -0.08 3993070.0 1020000.0 0.81 0.5195 0.6382 3633397 CBKinase1_023563 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O08 compound treatment 3296818.0 358000.0 0.3 3734238.0 758000.0 0.6 0.6406 0.9486 3633398 CBKinase1_023564 Cc1ccc(o1)C(=O)CSc2nnc(o2)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O09 compound treatment 3321133.0 382000.0 0.32 3747908.0 772000.0 0.62 0.6629 0.9546 3633399 CBKinase1_023565 CCn1c(SCC(=O)Nc2ccccc2C)nnc1c3ccccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O10 compound treatment 3016223.0 77300.0 0.07 3689220.0 713000.0 0.57 0.4479 0.7831 3633400 CBKinase1_023566 CCN(CC(=O)Nc1ccc(OC)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O11 mock treatment 3288208.0 349000.0 0.29 3673903.0 698000.0 0.56 0.6015 0.9559 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O12 mock treatment 3251670.0 313000.0 0.26 3679763.0 703000.0 0.56 0.583 0.9409 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O13 compound treatment 3511747.0 573000.0 0.48 3854872.0 879000.0 0.7 0.8368 0.9836 3633401 CBKinase1_023567 CCC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccccc3C(=O)N4CCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O14 compound treatment 3252367.0 313000.0 0.26 4051424.0 1080000.0 0.86 0.7929 0.8842 3633402 CBKinase1_023568 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2ccc(cc2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O15 compound treatment 3606511.0 668000.0 0.56 3595822.0 620000.0 0.49 0.7474 0.9979 3633403 CBKinase1_023569 Fc1ccc(cc1)S(=O)(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O16 compound treatment 3492124.0 553000.0 0.47 4019319.0 1040000.0 0.83 0.9178 0.9627 3633404 CBKinase1_023570 COc1cccc(NC(=O)Cn2cnc3c4cc5COC(C)(C)Cc5nc4sc3c2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O17 compound treatment 3707449.0 769000.0 0.65 4345152.0 1370000.0 1.09 1.2299 0.9691 3633405 CBKinase1_023571 Clc1cc(Cl)c(NC(=O)CSc2nnnn2c3ccccc3)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O18 compound treatment 3543187.0 604000.0 0.51 3937335.0 961000.0 0.77 0.9021 0.9804 3633406 CBKinase1_023572 COc1ccc(cc1OC)C(=O)CSc2cc(C)nc3nc(C)nn23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O19 compound treatment 4368034.0 1430000.0 1.21 3192753.0 216000.0 0.17 0.9744 0.8002 3633407 CBKinase1_023573 Cc1cc2c(=O)n(Cc3ccco3)c(SCC(=O)N4CCc5ccccc45)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O20 compound treatment 2897808.0 -41100.0 -0.03 3165617.0 189000.0 0.15 0.0822 0.5308 3633408 CBKinase1_023574 Cc1cc(C)n(CC(O)Cn2ccc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O21 compound treatment 4071751.0 1130000.0 0.96 4505742.0 1530000.0 1.22 1.5377 0.9927 3633409 CBKinase1_023575 COc1ccc(cc1OC)c2nn3c(Cn4cnc5ccccc45)nnc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O22 compound treatment 3571672.0 633000.0 0.53 3870059.0 894000.0 0.71 0.8811 0.9899 3633410 CBKinase1_023576 ONC(=O)CSc1nc2ccccc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O23 compound treatment 3685687.0 747000.0 0.63 4161486.0 1190000.0 0.94 1.1134 0.9806 3633411 CBKinase1_023577 CC1(C(C2CC1C=C2)C(=O)NCc3ccccc3)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 O24 compound treatment 3298840.0 360000.0 0.3 3501484.0 525000.0 0.42 0.5107 0.9876 3633412 CBKinase1_023578 Nc1cc(N)nc(SCc2n[nH]c(=S)n2CC=C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P01 compound treatment 2752573.0 -186000.0 -0.16 2432924.0 -543000.0 -0.43 -0.4174 -0.9059 3633413 CBKinase1_023579 O=C(COc1ccc(cc1)S(=O)(=O)N2CCOCC2)Nc3ccc4OCCOc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P02 compound treatment 2184389.0 -755000.0 -0.64 3466066.0 490000.0 0.39 -0.174 -0.233 3633414 CBKinase1_023580 COC(=O)Nc1sc2CCCc2c1C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P03 compound treatment 3748931.0 810000.0 0.68 3633937.0 658000.0 0.52 0.8538 0.9914 3633415 CBKinase1_023581 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P04 compound treatment 2922546.0 -16400.0 -0.01 2795252.0 -181000.0 -0.14 -0.1118 -0.7712 3633416 CBKinase1_023582 Clc1ccc(s1)C(=O)NCCCn2ccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P05 compound treatment 2406097.0 -533000.0 -0.45 3454119.0 478000.0 0.38 -0.0485 -0.0823 3633417 CBKinase1_023583 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(I)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P06 compound treatment 2541610.0 -397000.0 -0.34 3539725.0 563000.0 0.45 0.0806 0.1438 3633418 CBKinase1_023584 COc1ccccc1CNC(=O)c2cc3ccccc3oc2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P07 compound treatment 2133832.0 -805000.0 -0.68 2472407.0 -504000.0 -0.4 -0.7642 -0.9686 3633419 CBKinase1_023585 Cc1ccc2nc([nH]c2c1)c3ccc(NC(=O)CCN4C(=O)c5ccccc5C4=O)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P08 compound treatment 2712714.0 -226000.0 -0.19 2954803.0 -21500.0 -0.02 -0.147 -0.7675 3633420 CBKinase1_023586 CN1CCN(CC1)S(=O)(=O)c2ccc(Sc3nc4ccccc4[nH]3)c5nsnc25 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P09 compound treatment 2570421.0 -368000.0 -0.31 2841617.0 -135000.0 -0.11 -0.2957 -0.8992 3633421 CBKinase1_023587 CS(=O)(=O)N(CC(=O)N)c1cc(Cl)c(Cl)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P10 compound treatment 1595746.0 -1340000.0 -1.13 2939435.0 -36900.0 -0.03 -0.8219 -0.7252 3633422 CBKinase1_023588 Clc1ccc(cc1)c2nnc(SCCCN3C(=O)c4cccc5cccc(C3=O)c45)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P11 mock treatment 2481570.0 -457000.0 -0.39 2954816.0 -21500.0 -0.02 -0.2849 -0.7378 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P12 mock treatment 2912028.0 -26900.0 -0.02 2890665.0 -85600.0 -0.07 -0.0643 -0.894 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P13 compound treatment 2895571.0 -43300.0 -0.04 3163537.0 187000.0 0.15 0.0797 0.5186 3633423 CBKinase1_023589 O=C(NCCCn1ccnc1)c2csc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P14 compound treatment 3071472.0 133000.0 0.11 3244098.0 268000.0 0.21 0.23 0.9545 1161510 CBKinase1_023590 Cn1c(NCc2ccco2)nc3n(C)c(=O)n(Cc4ccc(Cl)cc4)c(=O)c13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P15 compound treatment 3327458.0 389000.0 0.33 3473167.0 497000.0 0.4 0.5118 0.9956 3633424 CBKinase1_023591 CCc1c(C)sc(NC(=O)COc2ccccc2)c1C(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P16 compound treatment 2917291.0 -21600.0 -0.02 3623404.0 647000.0 0.52 0.3518 0.6817 3633425 CBKinase1_023592 CC(C)(C)c1ccc(cc1)C(=O)Nc2cccc(NC(=O)COc3ccccc3Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P17 compound treatment 2704198.0 -235000.0 -0.2 3088784.0 112000.0 0.09 -0.0766 -0.3524 3633426 CBKinase1_023593 CCOc1ccccc1NC(=O)c2ccsc2NC(=O)c3ccoc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P18 compound treatment 3187349.0 248000.0 0.21 3389411.0 413000.0 0.33 0.381 0.9762 3633427 CBKinase1_023594 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2O)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P19 compound treatment 3790737.0 852000.0 0.72 3983676.0 1010000.0 0.8 1.0758 0.9985 3633428 CBKinase1_023595 COc1cccc2cc(C(=O)Nc3cccc(Cn4cccn4)c3)c(=O)oc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P20 compound treatment 3966284.0 1030000.0 0.87 3919899.0 944000.0 0.75 1.1446 0.9975 3633429 CBKinase1_023596 CC(C)c1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P21 compound treatment 3614764.0 676000.0 0.57 3334268.0 358000.0 0.29 0.6049 0.9488 3633430 CBKinase1_023597 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3csc4ccccc34)cc2)no1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P22 compound treatment 3859500.0 921000.0 0.78 3951966.0 976000.0 0.78 1.099 1.0 3633431 CBKinase1_023598 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P23 compound treatment 3659489.0 721000.0 0.61 3774616.0 798000.0 0.64 0.8797 0.9997 3633432 CBKinase1_023599 O=C(NCc1cccnc1)c2c(NC(=O)c3ccccc3)sc4CCCCCc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2397 P24 compound treatment 2867395.0 -71500.0 -0.06 2946633.0 -29700.0 -0.02 -0.0594 -0.9163 3633433 CBKinase1_023600 Cc1cc2nc(SCC(=O)c3ccc(O)cc3)[nH]c2cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A01 compound treatment 2067214.0 -1860000.0 -1.57 2512734.0 -1270000.0 -1.01 -1.8234 -0.9774 3633434 CBKinase1_023601 Clc1ccccc1NC(=O)CSc2nc(Nc3ccccc3)nc(n2)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A02 compound treatment 1710161.0 -2220000.0 -1.87 1911603.0 -1870000.0 -1.49 -2.3751 -0.9937 3633435 CBKinase1_023602 COc1ccc(cc1NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A03 compound treatment 3829001.0 -97600.0 -0.08 2145851.0 -1630000.0 -1.3 -0.9794 -0.7503 3633436 CBKinase1_023603 Cc1cccc(c1)n2c3NC(=O)C(NC(=O)CN4CCCC4=O)(c3c(=O)[nH]c2=S)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A04 compound treatment 3869540.0 -57000.0 -0.05 2419319.0 -1360000.0 -1.08 -0.8011 -0.7377 3633437 CBKinase1_023604 CC(C)N(Cc1nc(no1)c2ccc(Cl)cc2)C(=O)c3ccc(C)c(c3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A05 compound treatment 2515132.0 -1410000.0 -1.19 3734642.0 -45600.0 -0.04 -0.8676 -0.7284 3633438 CBKinase1_023605 Cc1c(Cl)cccc1NC(=O)COc2cc(O)c3c(=O)cc(oc3c2)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A06 compound treatment 3153678.0 -773000.0 -0.65 3600026.0 -180000.0 -0.14 -0.5626 -0.8427 3633439 CBKinase1_023606 Cc1c(sc2ncn(CC(=O)Nc3cc(Cl)ccc3Cl)c(=O)c12)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A07 compound treatment 2461948.0 -1460000.0 -1.24 2881792.0 -898000.0 -0.72 -1.38 -0.9664 1986535 CBKinase1_023607 Cn1c(SCc2ccon2)nc3ccccc3c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A08 compound treatment 3120568.0 -806000.0 -0.68 3386508.0 -394000.0 -0.31 -0.7027 -0.9384 3633440 CBKinase1_023608 COc1ccccc1NC(=O)CCN2C(=O)C3C4CCC(C4)C3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A09 compound treatment 3235229.0 -691000.0 -0.58 3224156.0 -556000.0 -0.44 -0.7258 -0.9908 3633441 CBKinase1_023609 O=C(NCc1ccccn1)c2ccccc2C(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A10 compound treatment 3783351.0 -143000.0 -0.12 3111172.0 -669000.0 -0.53 -0.4625 -0.8459 3633442 CBKinase1_023610 CCc1cccc(C)c1NC(=O)CSc2nnc([nH]2)c3ccccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A11 compound treatment 3425138.0 -501000.0 -0.42 3324865.0 -455000.0 -0.36 -0.5558 -0.9971 3633443 CBKinase1_023611 CSc1ccccc1NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A12 compound treatment 3649374.0 -277000.0 -0.23 3307037.0 -473000.0 -0.38 -0.4321 -0.9736 3633444 CBKinase1_023612 COc1ccc(F)cc1S(=O)(=O)Nc2cccc(c2)S(=O)(=O)N3CC4(C)CC3CC(C)(C)C4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A13 mock treatment 3803632.0 -123000.0 -0.1 3185079.0 -595000.0 -0.47 -0.4088 -0.8418 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A14 mock treatment 3801409.0 -125000.0 -0.11 3451998.0 -328000.0 -0.26 -0.2597 -0.9203 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A15 compound treatment 3960253.0 33700.0 0.03 3667658.0 -113000.0 -0.09 -0.0434 -0.4609 3633445 CBKinase1_023613 CC(Oc1cccc(Cl)c1)C(=O)Nc2ccccc2C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A16 compound treatment 3840332.0 -86300.0 -0.07 4010792.0 231000.0 0.18 0.0785 0.3971 3633446 CBKinase1_023614 Cc1cc(NC(=O)c2cc(on2)c3ccc(C)cc3)n(n1)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A17 compound treatment 4274036.0 347000.0 0.29 3536637.0 -244000.0 -0.19 0.0699 0.1989 3633447 CBKinase1_023615 O=C(NCCOc1nc(nc(n1)N2CCOCC2)N3CCCCC3)Nc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A18 compound treatment 4338702.0 412000.0 0.35 3148740.0 -632000.0 -0.5 -0.1101 -0.18 3633448 CBKinase1_023616 Clc1cc(C(=O)CSc2nc3sc4CCCc4c3c(=O)n2Cc5ccco5)c(Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A19 compound treatment 4248524.0 322000.0 0.27 3656247.0 -124000.0 -0.1 0.1221 0.4226 3633449 CBKinase1_023617 Cc1nc(c2ccccc2O)n(CCN3CCOCC3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A20 compound treatment 3450581.0 -476000.0 -0.4 3413029.0 -367000.0 -0.29 -0.4909 -0.9879 3633450 CBKinase1_023618 COc1ccccc1NC(=O)CSCC#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A21 compound treatment 3681890.0 -245000.0 -0.21 3570597.0 -210000.0 -0.17 -0.2641 -0.9945 3633451 CBKinase1_023619 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A22 compound treatment 3811255.0 -115000.0 -0.1 3778418.0 -1860.0 0.0 -0.0698 -0.7178 3633452 CBKinase1_023620 NC(=O)COc1c(oc2ccccc2c1=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A23 compound treatment 3719058.0 -208000.0 -0.18 3603780.0 -176000.0 -0.14 -0.2233 -0.9941 3633453 CBKinase1_023621 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3sc4CCCCc4c3C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 A24 compound treatment 2919944.0 -1010000.0 -0.85 2964890.0 -815000.0 -0.65 -1.06 -0.9913 3633454 CBKinase1_023622 [O-][N+](=O)c1ncn(CC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B01 compound treatment 2757754.0 -1170000.0 -0.99 3332898.0 -447000.0 -0.36 -0.9493 -0.9054 3633455 CBKinase1_023623 CC(C)(C)c1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B02 compound treatment 3290688.0 -636000.0 -0.54 3263502.0 -517000.0 -0.41 -0.6705 -0.9915 3633456 CBKinase1_023624 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(Cc3ccc(C)cc3)c4ccc(Cl)cc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B03 compound treatment 4586584.0 660000.0 0.56 2617120.0 -1160000.0 -0.93 -0.2619 -0.2422 3633457 CBKinase1_023625 NC(=O)C1(CCN(CC(=O)Nc2ccc(F)cc2)CC1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B04 compound treatment 3909767.0 -16800.0 -0.01 3954199.0 174000.0 0.14 0.088 0.6314 3633458 CBKinase1_023626 COc1ccc(NC(=O)Cn2cnc3sc(C)c(C)c3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B05 compound treatment 3467824.0 -459000.0 -0.39 3594861.0 -185000.0 -0.15 -0.3781 -0.9128 3633459 CBKinase1_023627 COC(=O)COc1ccc(NC(=O)C2CCCO2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B06 compound treatment 3853703.0 -72900.0 -0.06 4064256.0 284000.0 0.23 0.1166 0.497 3633460 CBKinase1_023628 COC(=O)c1ccccc1NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B07 compound treatment 3191456.0 -735000.0 -0.62 3589938.0 -190000.0 -0.15 -0.5457 -0.8549 3633461 CBKinase1_023629 CC(=O)c1ccc(NC(=O)CSc2nc(=O)cc(N)n2c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B08 compound treatment 3493335.0 -433000.0 -0.37 3496339.0 -284000.0 -0.23 -0.4184 -0.9735 3633462 CBKinase1_023630 Cc1nn(Cc2ccc(Br)cc2)c(C)c1NC(=O)Cn3nc(c4CCCCCc43)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B09 compound treatment 4126653.0 200000.0 0.17 3314422.0 -466000.0 -0.37 -0.1432 -0.3512 3633463 CBKinase1_023631 COc1ccc(cc1)C(=O)CSc2nnc(c3cccc(C)c3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B10 compound treatment 3983137.0 56600.0 0.05 3292846.0 -487000.0 -0.39 -0.241 -0.6157 3633464 CBKinase1_023632 CCOC(=O)c1c(C)c(C)sc1NC(=O)Cn2ccc(n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B11 compound treatment 4093087.0 167000.0 0.14 3228501.0 -552000.0 -0.44 -0.2117 -0.4585 3633465 CBKinase1_023633 CCN(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B12 compound treatment 4098620.0 172000.0 0.15 4438686.0 658000.0 0.52 0.4737 0.87 3633466 CBKinase1_023634 CCOC(=O)CNC(=O)c1cnn2cccnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B13 mock treatment 4456838.0 530000.0 0.45 4301207.0 521000.0 0.42 0.6099 0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B14 mock treatment 4267410.0 341000.0 0.29 3995807.0 216000.0 0.17 0.3248 0.9697 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B15 compound treatment 4416176.0 490000.0 0.41 4127794.0 348000.0 0.28 0.4879 0.9811 3633467 CBKinase1_023635 Cc1nnc(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B16 compound treatment 4080320.0 154000.0 0.13 3854301.0 74000.0 0.06 0.1334 0.9365 3633468 CBKinase1_023636 CCN(CC(=O)Nc1cccc([N+](=O)[O-])c1C)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B17 compound treatment 4115995.0 189000.0 0.16 3935537.0 155000.0 0.12 0.2005 0.992 3633469 CBKinase1_023637 CC(Sc1ncnc2sc(cc12)c3ccccc3)C(=O)Nc4cc(Cl)ccc4Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B18 compound treatment 4447243.0 521000.0 0.44 3865950.0 85700.0 0.07 0.3588 0.8074 3633470 CBKinase1_023638 Cc1ccccc1c2noc(CCC(=O)Nc3ccc(Cl)cc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B19 compound treatment 4826741.0 900000.0 0.76 4413398.0 633000.0 0.5 0.8937 0.9803 3633471 CBKinase1_023639 CCOc1ccc(NC(=O)Cn2cnc3sc(C(=O)N)c(C)c3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B20 compound treatment 4313122.0 387000.0 0.33 4571113.0 791000.0 0.63 0.6763 0.9529 3633472 CBKinase1_023640 C(c1nn2c(nnc2s1)C3COc4ccccc4O3)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B21 compound treatment 4712079.0 785000.0 0.66 4560631.0 780000.0 0.62 0.9083 0.9995 3633473 CBKinase1_023641 Fc1ccc(NC(=O)CSc2nnc(c3ccccc3F)n2c4ccc(Cl)cc4)c(F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B22 compound treatment 5103590.0 1180000.0 0.99 4580670.0 800000.0 0.64 1.1531 0.9771 3633474 CBKinase1_023642 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(F)(F)F)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B23 compound treatment 4456788.0 530000.0 0.45 4274025.0 494000.0 0.39 0.5945 0.998 3633475 CBKinase1_023643 COC(=O)C1CCc2sc(NC(=O)Nc3ccc(Cl)c(Cl)c3)c(C(=O)OC)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 B24 compound treatment 3552237.0 -374000.0 -0.32 3508794.0 -271000.0 -0.22 -0.3763 -0.983 3633476 CBKinase1_023644 CCS(=O)(=O)c1nc2ccccc2n1CC(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C01 compound treatment 2675551.0 -1250000.0 -1.06 2491645.0 -1290000.0 -1.03 -1.4724 -0.9999 3633477 CBKinase1_023645 Cc1cc(ccc1Br)N(CC(=O)Nc2cccc(c2)[N+](=O)[O-])S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C02 compound treatment 2730690.0 -1200000.0 -1.01 3007799.0 -772000.0 -0.62 -1.1486 -0.972 3633478 CBKinase1_023646 COc1c(Cl)cc(Cl)cc1CNCCNCC(C)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C03 compound treatment 2981032.0 -946000.0 -0.8 3109791.0 -670000.0 -0.53 -0.9419 -0.981 3633479 CBKinase1_023647 COc1cc(OC)cc(c1)C(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C04 compound treatment 3366340.0 -560000.0 -0.47 3340509.0 -440000.0 -0.35 -0.582 -0.9892 3633480 CBKinase1_023648 Cc1cc(C)c(NC(=O)CSc2nc(=O)cc(O)[nH]2)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C05 compound treatment 3650279.0 -276000.0 -0.23 3120270.0 -660000.0 -0.53 -0.5368 -0.9329 3633481 CBKinase1_023649 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C06 compound treatment 2964562.0 -962000.0 -0.81 3259358.0 -521000.0 -0.42 -0.8674 -0.9516 3633482 CBKinase1_023650 COc1ccc(CCNC(=O)C(=O)c2c([nH]c3ccccc23)c4ccccc4)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C07 compound treatment 3754758.0 -172000.0 -0.14 3293184.0 -487000.0 -0.39 -0.377 -0.9098 3633483 CBKinase1_023651 Cc1ccc(cc1)c2noc(CCC(=O)Nc3cccc(c3)[N+](=O)[O-])n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C08 compound treatment 3615550.0 -311000.0 -0.26 3134514.0 -646000.0 -0.51 -0.5495 -0.9511 3633484 CBKinase1_023652 Cc1c(sc2ncn(CC(=O)Nc3sc4CCCc4c3C#N)c(=O)c12)C(=O)Nc5ccc(C)cc5C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C09 compound treatment 2986068.0 -941000.0 -0.79 3310382.0 -470000.0 -0.37 -0.8258 -0.9413 3633485 CBKinase1_023653 COc1ccccc1N2CCN(CC2)C(=O)CSc3nc4c(N)ncnc4[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C10 compound treatment 3586047.0 -341000.0 -0.29 3479368.0 -301000.0 -0.24 -0.3727 -0.996 3633486 CBKinase1_023654 CCSc1nc2ccccc2n1Cc3nc(N)nc(n3)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C11 mock treatment 4276256.0 350000.0 0.29 3328253.0 -452000.0 -0.36 -0.0462 -0.0992 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C12 mock treatment 3447630.0 -479000.0 -0.4 3601233.0 -179000.0 -0.14 -0.3866 -0.9022 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C13 compound treatment 3875420.0 -51200.0 -0.04 3440623.0 -340000.0 -0.27 -0.2219 -0.8096 3633487 CBKinase1_023655 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccc(Br)cc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C14 compound treatment 3723866.0 -203000.0 -0.17 3609311.0 -171000.0 -0.14 -0.2173 -0.9937 3633488 CBKinase1_023656 Brc1ccc(cc1)C(=O)CSc2nnc(c3cccs3)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C15 mock treatment 4024681.0 98100.0 0.08 3919291.0 139000.0 0.11 0.1369 0.9897 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C16 mock treatment 3559477.0 -367000.0 -0.31 3689979.0 -90300.0 -0.07 -0.2699 -0.8488 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C17 compound treatment 4034063.0 107000.0 0.09 3646245.0 -134000.0 -0.11 -0.0114 -0.0816 3633489 CBKinase1_023657 COC(=O)c1c(C)n(CCNc2ccc(cc2)[N+](=O)[O-])c3ccc(O)cc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C18 compound treatment 3987865.0 61300.0 0.05 3828922.0 48600.0 0.04 0.064 0.99 3633490 CBKinase1_023658 Cc1cc(nc(SCC(=O)Nc2sc3CCCCc3c2C#N)n1)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C19 compound treatment 4618536.0 692000.0 0.58 4354298.0 574000.0 0.46 0.7362 0.9927 3633491 CBKinase1_023659 C(Cn1c(NCc2ccccn2)nc3ccccc13)N4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C20 compound treatment 4207935.0 281000.0 0.24 4410631.0 630000.0 0.5 0.5231 0.9414 3633492 CBKinase1_023660 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3sc4CCCc4c3C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C21 compound treatment 4426164.0 500000.0 0.42 4364805.0 585000.0 0.47 0.6274 0.9987 3633493 CBKinase1_023661 OC(=O)C(Cc1ccccc1)NC(=O)Nc2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C22 compound treatment 4389602.0 463000.0 0.39 4307606.0 527000.0 0.42 0.5734 0.9993 3633494 CBKinase1_023662 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2c(C)cc(C)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C23 compound treatment 4181470.0 255000.0 0.21 3448500.0 -332000.0 -0.26 -0.035 -0.1026 3633495 CBKinase1_023663 CCn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3ccc(Cl)cc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 C24 compound treatment 3222608.0 -704000.0 -0.59 2917323.0 -863000.0 -0.69 -0.9062 -0.9973 3633496 CBKinase1_023664 O=C(Nc1cccc2ccccc12)C(Cc3ccccc3)N4C(=O)C5C6CCC(C6)C5C4=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D01 compound treatment 2618038.0 -1310000.0 -1.1 2998300.0 -782000.0 -0.62 -1.2212 -0.9634 3088160 CBKinase1_023665 COC(=O)C(NS(=O)(=O)c1ccc(cc1)N2CCCC2=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D02 compound treatment 3088072.0 -839000.0 -0.71 3133078.0 -647000.0 -0.52 -0.8649 -0.988 3633497 CBKinase1_023666 Cc1nn(CC(=O)Nc2ccc(I)cc2C)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D03 compound treatment 3436658.0 -490000.0 -0.41 4077927.0 298000.0 0.24 -0.1245 -0.2612 3633498 CBKinase1_023667 CN1CCN(CC1)c2ccccc2NC(=O)COc3cc(C)c(Cl)c(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D04 compound treatment 3364992.0 -562000.0 -0.47 3825414.0 45100.0 0.04 -0.3095 -0.6515 3121485 CBKinase1_023668 CSc1nsc(SCC(=O)N2CCCc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D05 compound treatment 3713662.0 -213000.0 -0.18 3775049.0 -5230.0 0.0 -0.1299 -0.7233 1310551 CBKinase1_023669 COc1cc2c(cc1NC(=O)COC(=O)C)oc3ccccc32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D06 compound treatment 3617855.0 -309000.0 -0.26 3827818.0 47500.0 0.04 -0.1573 -0.5979 3633499 CBKinase1_023670 CCc1ccccc1NC(=O)C(C)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D07 compound treatment 3516377.0 -410000.0 -0.35 3594431.0 -186000.0 -0.15 -0.3494 -0.9283 3633500 CBKinase1_023671 Cc1ccc(C)c(NC(=O)c2ccc(OCC(=O)Nc3cc(ccc3Cl)C(F)(F)F)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D08 compound treatment 3662921.0 -264000.0 -0.22 3703031.0 -77200.0 -0.06 -0.2008 -0.8701 3633501 CBKinase1_023672 Cn1c(NCCCN)nc2n(C)c(=O)n(Cc3ccccc3Cl)c(=O)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D09 compound treatment 3322488.0 -604000.0 -0.51 3613097.0 -167000.0 -0.13 -0.4545 -0.863 3633502 CBKinase1_023673 CSc1nsc(SCC(=O)Oc2ccc(NC(=O)C)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D10 compound treatment 3415092.0 -511000.0 -0.43 4025943.0 246000.0 0.2 -0.1666 -0.3517 3633503 CBKinase1_023674 COc1ccc(OC)c(NC(=O)CSc2nc(C)cc(C)n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D11 mock treatment 3462418.0 -464000.0 -0.39 3554912.0 -225000.0 -0.18 -0.4039 -0.9376 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D12 mock treatment 3722900.0 -204000.0 -0.17 3954556.0 174000.0 0.14 -0.0233 -0.1053 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D13 compound treatment 3643008.0 -284000.0 -0.24 4146279.0 366000.0 0.29 0.0371 0.0984 3633504 CBKinase1_023675 Fc1ccccc1c2noc(CCC(=O)Nc3ccccc3Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D14 compound treatment 3521092.0 -405000.0 -0.34 3749636.0 -30600.0 -0.02 -0.2591 -0.7557 3633505 CBKinase1_023676 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccco5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D15 mock treatment 3772486.0 -154000.0 -0.13 3918210.0 138000.0 0.11 -0.0142 -0.0833 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D16 mock treatment 3740550.0 -186000.0 -0.16 3959401.0 179000.0 0.14 -0.01 -0.0472 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D17 compound treatment 4175509.0 249000.0 0.21 4120701.0 340000.0 0.27 0.3403 0.992 3633506 CBKinase1_023677 Cn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D18 compound treatment 3744503.0 -182000.0 -0.15 3956939.0 177000.0 0.14 -0.009 -0.0434 3633507 CBKinase1_023678 Clc1ccc(c2nnc(SCc3ccon3)o2)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D19 compound treatment 4042760.0 116000.0 0.1 4089167.0 309000.0 0.25 0.2434 0.9185 3633508 CBKinase1_023679 Cc1c(Cl)cccc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D20 compound treatment 4246124.0 320000.0 0.27 4014652.0 234000.0 0.19 0.3227 0.984 3633509 CBKinase1_023680 CCOc1ccc(cc1)C(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D21 compound treatment 3896725.0 -29900.0 -0.03 4098488.0 318000.0 0.25 0.1615 0.6338 3633510 CBKinase1_023681 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3C)nnc2c4ccccc4F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D22 compound treatment 3948782.0 22200.0 0.02 4068636.0 288000.0 0.23 0.1758 0.7622 3633511 CBKinase1_023682 Clc1cccc2cccc(c12)S(=O)(=O)NCCOc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D23 compound treatment 4209693.0 283000.0 0.24 4035501.0 255000.0 0.2 0.3127 0.9968 3633512 CBKinase1_023683 Clc1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 D24 compound treatment 3776713.0 -150000.0 -0.13 3548769.0 -232000.0 -0.18 -0.2199 -0.983 3633513 CBKinase1_023684 CCOC(=O)C1=C(Cn2cnc3ccccc23)NC(=O)NC1c4cc(C)ccc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E01 mock treatment 1142874.0 -2780000.0 -2.35 1332270.0 -2450000.0 -1.95 -3.04 -0.9958 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E02 mock treatment 1476285.0 -2450000.0 -2.07 1756604.0 -2020000.0 -1.61 -2.602 -0.9925 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E03 compound treatment 1837169.0 -2090000.0 -1.76 1747056.0 -2030000.0 -1.62 -2.3921 -0.9991 3633514 CBKinase1_023685 COc1ccc(OC)c(NC(=O)Cc2coc3ccc(C)cc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E04 compound treatment 2041623.0 -1880000.0 -1.59 2276183.0 -1500000.0 -1.2 -1.972 -0.9903 3633515 CBKinase1_023686 Cn1c(Cc2ccc(Cl)cc2)nnc1SCc3nc4ccccc4c(=O)n3c5cccc(c5)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E05 compound treatment 2211180.0 -1720000.0 -1.45 2001285.0 -1780000.0 -1.42 -2.0258 -0.9999 3633516 CBKinase1_023687 FC(F)(F)c1cc(Cl)ccc1NC(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E06 compound treatment 3226332.0 -700000.0 -0.59 2205749.0 -1570000.0 -1.25 -1.3051 -0.9409 3633517 CBKinase1_023688 CCN(CC(=O)Nc1ccc(OC)cc1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E07 compound treatment 1595018.0 -2330000.0 -1.97 1557379.0 -2220000.0 -1.77 -2.6435 -0.9986 3633518 CBKinase1_023689 Cc1ccc(cc1)c2cc(no2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E08 compound treatment 2277798.0 -1650000.0 -1.39 2102904.0 -1680000.0 -1.34 -1.9288 -0.9998 3633519 CBKinase1_023690 Cc1cc(ccc1Br)N(CC(=O)Nc2ccccc2C(=O)N3CCCC3)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E09 mock treatment 2403869.0 -1520000.0 -1.28 2498134.0 -1280000.0 -1.02 -1.6308 -0.9936 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E10 mock treatment 2914768.0 -1010000.0 -0.85 2323106.0 -1460000.0 -1.16 -1.4247 -0.9885 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E11 compound treatment 2548476.0 -1380000.0 -1.16 2510921.0 -1270000.0 -1.01 -1.5374 -0.9976 3633520 CBKinase1_023691 Cn1c(CN2CCCC2)nc3cc(NC(=O)COc4ccc(Cl)cc4)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E12 compound treatment 2728356.0 -1200000.0 -1.01 2613030.0 -1170000.0 -0.93 -1.3725 -0.9991 3633521 CBKinase1_023692 O=C(NCc1cccnc1)C2CCCN(C2)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E13 compound treatment 2473033.0 -1450000.0 -1.23 2456694.0 -1320000.0 -1.05 -1.6129 -0.9972 3633522 CBKinase1_023693 Cc1cc(C)n2nc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E14 compound treatment 2597432.0 -1330000.0 -1.12 2285356.0 -1490000.0 -1.19 -1.6353 -0.9995 3633523 CBKinase1_023694 COC(=O)c1cccc(NC(=O)CSc2nc3cc4ccccc4cc3[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E15 compound treatment 2567828.0 -1360000.0 -1.15 2444581.0 -1340000.0 -1.06 -1.5632 -0.9993 3633524 CBKinase1_023695 CCN(CC(=O)Nc1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E16 compound treatment 2556828.0 -1370000.0 -1.16 2669810.0 -1110000.0 -0.89 -1.4428 -0.9913 3633525 CBKinase1_023696 Cc1nc2ccccc2nc1CSc3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E17 mock treatment 2742299.0 -1180000.0 -1.0 2737903.0 -1040000.0 -0.83 -1.2938 -0.9958 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E18 mock treatment 3050993.0 -876000.0 -0.74 2739473.0 -1040000.0 -0.83 -1.1088 -0.9983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E19 compound treatment 2922110.0 -1000000.0 -0.85 2870725.0 -910000.0 -0.72 -1.1117 -0.997 3633526 CBKinase1_023697 CCN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E20 compound treatment 2543525.0 -1380000.0 -1.17 2949068.0 -831000.0 -0.66 -1.2934 -0.9641 3633527 CBKinase1_023698 Cc1nnc2c3ccccc3c(nn12)c4ccc(C)c(c4)S(=O)(=O)NCc5ccco5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E21 compound treatment 2741631.0 -1180000.0 -1.0 3208719.0 -572000.0 -0.46 -1.0289 -0.9367 3633528 CBKinase1_023699 CCOc1ccc(NC(=O)C(C)O)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E22 compound treatment 3207177.0 -719000.0 -0.61 3001257.0 -779000.0 -0.62 -0.8681 -0.9999 3633529 CBKinase1_023700 CCc1cc(C)cc(OCCNC(=O)c2nc[nH]n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E23 compound treatment 3301062.0 -626000.0 -0.53 3606051.0 -174000.0 -0.14 -0.4713 -0.8638 3633530 CBKinase1_023701 Fc1c(F)c(F)c(C(=O)NCc2nc3ccccc3[nH]2)c(F)c1F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 E24 compound treatment 2724074.0 -1200000.0 -1.01 2878602.0 -902000.0 -0.72 -1.2254 -0.9858 3212338 CBKinase1_023702 Cc1nc2ccccc2nc1CSc3nnc(Cc4ccccc4)n3c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F01 mock treatment 2051463.0 -1880000.0 -1.58 1641819.0 -2140000.0 -1.7 -2.3236 -0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F02 mock treatment 2295674.0 -1630000.0 -1.38 1864924.0 -1920000.0 -1.53 -2.0522 -0.9987 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F03 compound treatment 2640213.0 -1290000.0 -1.09 2012664.0 -1770000.0 -1.41 -1.7635 -0.9917 3030004 CBKinase1_023703 CCOC(=O)CSc1nc2ccccc2n3cnnc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F04 compound treatment 2671531.0 -1260000.0 -1.06 2183173.0 -1600000.0 -1.27 -1.6487 -0.9958 3633531 CBKinase1_023704 COc1cc(NC(=O)COc2ccccc2[N+](=O)[O-])ccc1NC(=O)c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F05 compound treatment 3474943.0 -452000.0 -0.38 2281869.0 -1500000.0 -1.19 -1.1139 -0.8886 3633532 CBKinase1_023705 COc1cccc(OCC(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F06 compound treatment 2206587.0 -1720000.0 -1.45 2257793.0 -1520000.0 -1.21 -1.8839 -0.9961 3633533 CBKinase1_023706 Cc1nnc(SCc2cc(=O)[nH]c(n2)N3CCN(Cc4ccccc4)CC3)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F07 compound treatment 2094083.0 -1830000.0 -1.55 2606074.0 -1170000.0 -0.94 -1.7548 -0.9711 3633534 CBKinase1_023707 COc1ccc(CCNC(=O)C(=O)c2c(C)[nH]c3ccccc23)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F08 compound treatment 2739151.0 -1190000.0 -1.0 2590723.0 -1190000.0 -0.95 -1.3787 -0.9996 3633535 CBKinase1_023708 [O-][N+](=O)c1ccn(CC(=O)N2CCOCC2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F09 mock treatment 2367262.0 -1560000.0 -1.32 2578001.0 -1200000.0 -0.96 -1.6076 -0.9879 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F10 mock treatment 2495608.0 -1430000.0 -1.21 2451629.0 -1330000.0 -1.06 -1.6023 -0.9979 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F11 compound treatment 2576993.0 -1350000.0 -1.14 2430215.0 -1350000.0 -1.08 -1.5658 -0.9996 3633536 CBKinase1_023709 [O-][N+](=O)c1ccccc1NC(=O)CCc2nc(no2)c3ccccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F12 compound treatment 1137257.0 -2790000.0 -2.35 926055.0 -2850000.0 -2.27 -3.2723 -0.9999 3633537 CBKinase1_023710 NCCCN(Cc1ccco1)C2CCCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F13 compound treatment 2427277.0 -1500000.0 -1.26 2107688.0 -1670000.0 -1.33 -1.8369 -0.9997 3633538 CBKinase1_023711 CCOc1ccc(cc1)n2c(SCc3nc(no3)c4ccc(C)cc4)nnc2c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F14 compound treatment 2502402.0 -1420000.0 -1.2 2476260.0 -1300000.0 -1.04 -1.5844 -0.9974 3633539 CBKinase1_023712 CC(=O)NCCc1nc2cc(NC(=O)c3ccco3)ccc2n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F15 compound treatment 2172418.0 -1750000.0 -1.48 2155858.0 -1620000.0 -1.29 -1.9618 -0.9978 3633540 CBKinase1_023713 COc1ccc(NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F16 compound treatment 2657608.0 -1270000.0 -1.07 2454795.0 -1330000.0 -1.06 -1.5039 -1.0 3633541 CBKinase1_023714 COc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F17 mock treatment 2907129.0 -1020000.0 -0.86 2297998.0 -1480000.0 -1.18 -1.4435 -0.9878 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F18 mock treatment 2779796.0 -1150000.0 -0.97 2843615.0 -937000.0 -0.75 -1.2119 -0.9918 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F19 compound treatment 3133964.0 -793000.0 -0.67 3255526.0 -525000.0 -0.42 -0.7685 -0.9745 3088062 CBKinase1_023715 CC1CCc2c(C1)sc3nc(SCc4nc5ccccc5nc4C)n(C)c(=O)c23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F20 compound treatment 3499015.0 -428000.0 -0.36 3064297.0 -716000.0 -0.57 -0.6585 -0.9755 3633542 CBKinase1_023716 O=C1N(CCc2nc3c4c5CCCCCc5sc4ncn3n2)C(=O)c6ccccc16 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F21 compound treatment 3261413.0 -665000.0 -0.56 3222062.0 -558000.0 -0.44 -0.7113 -0.9934 3633543 CBKinase1_023717 Cn1c(SCC(=O)Nc2cccc3ccccc23)nnc1c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F22 compound treatment 2934333.0 -992000.0 -0.84 2974291.0 -806000.0 -0.64 -1.0461 -0.9915 3633544 CBKinase1_023718 COc1ccc(CC(=O)Nc2cccc(c2)c3nnc(o3)c4ccc(C)cc4)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F23 compound treatment 2718662.0 -1210000.0 -1.02 2995427.0 -785000.0 -0.63 -1.1628 -0.9726 3633545 CBKinase1_023719 Cc1cc(=O)oc2cc(OCC(=O)Nc3sc4CCCc4c3C#N)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 F24 compound treatment 2602503.0 -1320000.0 -1.12 2839763.0 -941000.0 -0.75 -1.3198 -0.9812 3633546 CBKinase1_023720 Fc1ccc(cc1)n2c(SCc3nc(no3)c4cccs4)nnc2c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G01 compound treatment 2543342.0 -1380000.0 -1.17 1914701.0 -1870000.0 -1.49 -1.8765 -0.9928 3633547 CBKinase1_023721 Cc1cc(Cl)ccc1NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G02 compound treatment 3253925.0 -673000.0 -0.57 2932001.0 -848000.0 -0.68 -0.8793 -0.9962 3041413 CBKinase1_023722 CC(=O)NCCc1nc2cc(NC(=O)C)ccc2n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G03 mock treatment 3155683.0 -771000.0 -0.65 3092475.0 -688000.0 -0.55 -0.8474 -0.9964 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G04 mock treatment 3488020.0 -439000.0 -0.37 4086830.0 307000.0 0.24 -0.0888 -0.2003 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G05 compound treatment 3714459.0 -212000.0 -0.18 3825436.0 45200.0 0.04 -0.1011 -0.5538 3633548 CBKinase1_023723 COc1ccc(cc1)c2nnc(SCc3nc4ccccc4c(=O)[nH]3)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G06 compound treatment 3753192.0 -173000.0 -0.15 4049953.0 270000.0 0.21 0.0486 0.1868 3633549 CBKinase1_023724 Cc1cc(ccc1NC(=O)CSc2nnnn2c3ccccc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G07 compound treatment 3246020.0 -681000.0 -0.57 3751371.0 -28900.0 -0.02 -0.4222 -0.7349 3633550 CBKinase1_023725 CN1CCN(CC(=O)Nc2sc3CCCCc3c2C(=O)Nc4ccccc4)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G08 compound treatment 3736933.0 -190000.0 -0.16 4092602.0 312000.0 0.25 0.0629 0.2126 3633551 CBKinase1_023726 Cc1ccccc1c2nnc(SCC(=O)c3cccc(c3)[N+](=O)[O-])[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G09 compound treatment 3297349.0 -629000.0 -0.53 3416384.0 -364000.0 -0.29 -0.5804 -0.9596 3633552 CBKinase1_023727 FC(F)(F)c1cc(NC(=O)COc2ccc(cc2)S(=O)(=O)N3CCOCC3)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G10 compound treatment 3588169.0 -338000.0 -0.29 3409507.0 -371000.0 -0.3 -0.4108 -0.9998 3633553 CBKinase1_023728 COc1cccc(c1)c2cc(n3nc(cc3n2)C(=O)NCc4ccccn4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G11 compound treatment 3782293.0 -144000.0 -0.12 3113529.0 -667000.0 -0.53 -0.4618 -0.8471 3633554 CBKinase1_023729 C(c1nnc2sc(nn12)C3COc4ccccc4O3)n5cnc6ccccc56 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G12 compound treatment 2518730.0 -1410000.0 -1.19 2560835.0 -1220000.0 -0.97 -1.527 -0.9951 3633555 CBKinase1_023730 Cc1nn2c(nnc2c3ccccc13)c4cccc(NC(=O)CN5CCOCC5)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G13 compound treatment 3390170.0 -536000.0 -0.45 3192773.0 -588000.0 -0.47 -0.6511 -0.9999 3633556 CBKinase1_023731 Cc1nnc2c3ccccc3c(nn12)c4ccc(C)c(c4)S(=O)(=O)NCC5CCCO5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G14 compound treatment 3801628.0 -125000.0 -0.11 3371898.0 -408000.0 -0.33 -0.3047 -0.8906 3633557 CBKinase1_023732 CC(C)N(Cc1nc(no1)c2ccccc2Cl)S(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G15 compound treatment 3936446.0 9860.0 0.01 3667604.0 -113000.0 -0.09 -0.0576 -0.6389 3633558 CBKinase1_023733 [O-][N+](=O)c1cnn(CCCC(=O)Nc2ccc(F)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G16 compound treatment 1691342.0 -2240000.0 -1.89 1815567.0 -1960000.0 -1.57 -2.4405 -0.9957 3633559 CBKinase1_023734 Cc1cc(nc(SCC(=O)Nc2ccc(Cl)cc2)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G17 compound treatment 4224260.0 298000.0 0.25 3545748.0 -235000.0 -0.19 0.0454 0.1449 3633560 CBKinase1_023735 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cccc(Cl)c2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G18 compound treatment 4101173.0 175000.0 0.15 3817912.0 37600.0 0.03 0.1253 0.834 3633561 CBKinase1_023736 Cc1cc(C)n2nc(SCC(=O)c3ccc4CCc5cccc3c54)nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G19 mock treatment 3699066.0 -228000.0 -0.19 3648097.0 -132000.0 -0.11 -0.2102 -0.9601 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G20 mock treatment 4133216.0 207000.0 0.17 4149410.0 369000.0 0.29 0.3313 0.9688 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G21 compound treatment 4573839.0 647000.0 0.55 4232680.0 452000.0 0.36 0.641 0.9797 3633562 CBKinase1_023737 CCc1c(C)sc(NC(=O)C2CC(=NO2)c3cc(Cl)c(OC)cc3OC)c1C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G22 compound treatment 3994605.0 68000.0 0.06 4317446.0 537000.0 0.43 0.3433 0.7948 3633563 CBKinase1_023738 OC(=O)COc1c(oc2ccccc2c1=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G23 compound treatment 3971941.0 45400.0 0.04 3578033.0 -202000.0 -0.16 -0.0869 -0.5247 3633564 CBKinase1_023739 CCN(CC(=O)Nc1cccc(F)c1)S(=O)(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 G24 compound treatment 3528754.0 -398000.0 -0.34 3367327.0 -413000.0 -0.33 -0.47 -1.0 3633565 CBKinase1_023740 Cc1cc(C)n2nc(SCC(=O)Nc3ccccc3[N+](=O)[O-])nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H01 compound treatment 2575899.0 -1350000.0 -1.14 2843698.0 -937000.0 -0.75 -1.3335 -0.979 3633566 CBKinase1_023741 COc1cccc(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H02 compound treatment 3256794.0 -670000.0 -0.56 3372842.0 -407000.0 -0.32 -0.6291 -0.9654 3035211 CBKinase1_023742 Cn1c2ccccc2c3nnc(SCCCC(=O)c4ccc(F)cc4)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H03 mock treatment 3787853.0 -139000.0 -0.12 3622380.0 -158000.0 -0.13 -0.1717 -0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H04 mock treatment 3768246.0 -158000.0 -0.13 3165283.0 -615000.0 -0.49 -0.441 -0.8681 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H05 compound treatment 3689078.0 -238000.0 -0.2 3749734.0 -30500.0 -0.02 -0.1589 -0.7872 3633567 CBKinase1_023743 COc1cccc(NC(=O)CCc2nc(no2)c3ccc(OC)c(OC)c3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H06 compound treatment 3395107.0 -531000.0 -0.45 3253910.0 -526000.0 -0.42 -0.6137 -0.9995 3633568 CBKinase1_023744 COc1ccc(cc1OC)c2cc(nc(SCC(=O)Nc3cc(F)ccc3C)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H07 compound treatment 3645264.0 -281000.0 -0.24 3098047.0 -682000.0 -0.54 -0.5523 -0.9309 3633569 CBKinase1_023745 Cc1ccc(c(C)c1)n2c(SCC(=O)Nc3ccc(C)c(Cl)c3)nnc2c4ccccc4O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H08 compound treatment 3966240.0 39700.0 0.03 3425948.0 -354000.0 -0.28 -0.176 -0.619 3633570 CBKinase1_023746 COc1ccc(Cl)cc1NC(=O)C(C)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H09 compound treatment 3456126.0 -470000.0 -0.4 3072889.0 -707000.0 -0.56 -0.6793 -0.9852 3633571 CBKinase1_023747 CCn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3cc(Br)ccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H10 compound treatment 4096195.0 170000.0 0.14 3236593.0 -544000.0 -0.43 -0.2053 -0.4498 3633572 CBKinase1_023748 CC(C)N(Cc1nc(no1)c2cccc(C)c2)C(=O)c3ccc(Br)o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H11 compound treatment 4375030.0 448000.0 0.38 3977041.0 197000.0 0.16 0.3784 0.924 3633573 CBKinase1_023749 Cc1ccc(NC(=O)CSCC(=O)N)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H12 compound treatment 3803408.0 -123000.0 -0.1 3600760.0 -180000.0 -0.14 -0.1746 -0.9876 3633574 CBKinase1_023750 OC1(CC(=O)c2ccc(NC(=O)C3CC3)cc2)C(=O)Nc4ccccc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H13 compound treatment 2431705.0 -1490000.0 -1.26 2319193.0 -1460000.0 -1.16 -1.7151 -0.9992 3633575 CBKinase1_023751 [O-][N+](=O)c1nn(c2ccc(Cl)cc2)[n+]([O-])c1NCC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H14 compound treatment 3957272.0 30700.0 0.03 3424717.0 -356000.0 -0.28 -0.1821 -0.6399 3633576 CBKinase1_023752 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccccc3Sc4ccccc4)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H15 compound treatment 3873716.0 -52900.0 -0.04 3572521.0 -208000.0 -0.17 -0.1486 -0.8667 1521891 CBKinase1_023753 O=c1n(c(SCc2nc3ccccc3[nH]2)nc4sc5CCCc5c14)c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H16 compound treatment 3892849.0 -33700.0 -0.03 3907286.0 127000.0 0.1 0.0515 0.4894 3633577 CBKinase1_023754 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H17 compound treatment 4541036.0 614000.0 0.52 4013864.0 234000.0 0.19 0.4981 0.9045 3633578 CBKinase1_023755 FC(F)(F)c1ccc2sc(SCCNC(=O)C3(CC4CC5CC(C4)C3)C5)nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H18 compound treatment 4111725.0 185000.0 0.16 4062314.0 282000.0 0.22 0.2694 0.9842 3633579 CBKinase1_023756 NC(=O)COc1ccc(NC(=O)c2cncc(Br)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H19 mock treatment 3557911.0 -369000.0 -0.31 3489058.0 -291000.0 -0.23 -0.384 -0.9896 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H20 mock treatment 4970533.0 1040000.0 0.88 4437069.0 657000.0 0.52 0.9928 0.9692 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H21 compound treatment 4707346.0 781000.0 0.66 4829050.0 1050000.0 0.84 1.0568 0.993 3633580 CBKinase1_023757 Cn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H22 compound treatment 4786332.0 860000.0 0.73 4830146.0 1050000.0 0.84 1.1045 0.9975 3633581 CBKinase1_023758 COc1ccc(cc1OC)C(=O)N(Cc2nc(no2)c3ccc(C)cc3)C4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H23 compound treatment 4337270.0 411000.0 0.35 4407361.0 627000.0 0.5 0.5984 0.984 3633582 CBKinase1_023759 COc1cc(ccc1NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 H24 compound treatment 3937200.0 10600.0 0.01 3454356.0 -326000.0 -0.26 -0.1774 -0.6823 3633583 CBKinase1_023760 COc1cc2[nH]c(=S)n(CCc3c[nH]cn3)c(=O)c2cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I01 compound treatment 2874743.0 -1050000.0 -0.89 2549347.0 -1230000.0 -0.98 -1.3211 -0.9987 3633584 CBKinase1_023761 [O-][N+](=O)c1ccn(CC(=O)Nc2ccc(F)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I02 compound treatment 3409807.0 -517000.0 -0.44 3226752.0 -554000.0 -0.44 -0.6202 -1.0 3633585 CBKinase1_023762 Cc1nn(CC(=O)Nc2ccc(C)c(C)c2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I03 compound treatment 3681997.0 -245000.0 -0.21 3699226.0 -81000.0 -0.06 -0.1916 -0.8861 3633586 CBKinase1_023763 C=CCn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I04 compound treatment 3302325.0 -624000.0 -0.53 3579610.0 -201000.0 -0.16 -0.4854 -0.8821 3633587 CBKinase1_023764 COc1ccc(cc1)c2cc(nc(SCc3cccc(c3)C(=O)O)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I05 mock treatment 3559399.0 -367000.0 -0.31 3747372.0 -32900.0 -0.03 -0.2376 -0.7642 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I06 mock treatment 3287138.0 -639000.0 -0.54 3823299.0 43000.0 0.03 -0.3571 -0.6608 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I07 compound treatment 3806275.0 -120000.0 -0.1 3157992.0 -622000.0 -0.5 -0.4225 -0.8345 3633588 CBKinase1_023765 Cn1c(=O)n(C)c2cc(CNCc3cccnc3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I08 compound treatment 3830124.0 -96500.0 -0.08 3443467.0 -337000.0 -0.27 -0.2474 -0.8818 3633589 CBKinase1_023766 Cn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3cc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I09 compound treatment 3435802.0 -491000.0 -0.41 3084462.0 -696000.0 -0.55 -0.6849 -0.9896 3633590 CBKinase1_023767 COc1ccccc1n2c(CSc3nc4cc(ccc4s3)C(=O)N5CCCC5)nc6ccccc6c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I10 compound treatment 3677090.0 -249000.0 -0.21 3116843.0 -663000.0 -0.53 -0.5227 -0.9185 3633591 CBKinase1_023768 C1Oc2ccccc2OC1c3nnc4sc(/C=C/c5ccccc5)nn34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I11 compound treatment 4050706.0 124000.0 0.1 3323807.0 -456000.0 -0.36 -0.1832 -0.484 3633593 CBKinase1_023769 CC(=O)c1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I12 compound treatment 4353664.0 427000.0 0.36 4198886.0 419000.0 0.33 0.4907 0.9993 3633594 CBKinase1_023770 COc1cc(OC)c(cc1Cl)C2=NOC(C2)C(=O)Nc3cc(C)nn3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I13 compound treatment 3715770.0 -211000.0 -0.18 3921398.0 141000.0 0.11 -0.0462 -0.2196 3633595 CBKinase1_023771 COCCNC(=O)CC1Sc2ccccc2NC1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I14 compound treatment 3644872.0 -282000.0 -0.24 3825253.0 45000.0 0.04 -0.1427 -0.5937 3633596 CBKinase1_023772 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5cccnc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I15 compound treatment 4355210.0 429000.0 0.36 3250631.0 -530000.0 -0.42 -0.0429 -0.0771 3633597 CBKinase1_023773 C(Oc1ccccc1)c2nn3c(Cn4cnc5ccccc45)nnc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I16 compound treatment 4214993.0 288000.0 0.24 3688476.0 -91800.0 -0.07 0.1203 0.4735 3633598 CBKinase1_023774 COC(=O)c1cccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I17 compound treatment 4358674.0 432000.0 0.36 3501038.0 -279000.0 -0.22 0.1003 0.235 3633599 CBKinase1_023775 CC(=O)NCCc1nc2cc(NC(=O)c3ccccc3)ccc2n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I18 compound treatment 4234645.0 308000.0 0.26 4497576.0 717000.0 0.57 0.588 0.9363 3633600 CBKinase1_023776 Cc1ccc(cc1)c2cc(C)nc(SCC(=O)Nc3ccc(F)cc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I19 compound treatment 5094512.0 1170000.0 0.99 4442813.0 663000.0 0.53 1.07 0.9573 3633601 CBKinase1_023777 COc1ccc(cc1Cl)S(=O)(=O)N(CC(=O)Nc2ccccc2F)C3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I20 compound treatment 4530814.0 604000.0 0.51 4554832.0 775000.0 0.62 0.7969 0.9955 3633602 CBKinase1_023778 COc1ccc(cc1OC)C(=O)CSc2nc3nc(C)cc(C)n3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I21 mock treatment 4719964.0 793000.0 0.67 5331868.0 1550000.0 1.24 1.3477 0.9584 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I22 mock treatment 4840897.0 914000.0 0.77 4261068.0 481000.0 0.38 0.8163 0.9479 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I23 compound treatment 4527488.0 601000.0 0.51 3971420.0 191000.0 0.15 0.4661 0.8807 3633603 CBKinase1_023779 CCc1cccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 I24 compound treatment 3621150.0 -305000.0 -0.26 3415947.0 -364000.0 -0.29 -0.3875 -0.9982 3633604 CBKinase1_023780 CC(=O)c1cn(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J01 compound treatment 3436283.0 -490000.0 -0.41 3159058.0 -621000.0 -0.5 -0.6426 -0.996 3633605 CBKinase1_023781 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cc(Cl)ccc2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J02 compound treatment 4014949.0 88400.0 0.07 3989714.0 209000.0 0.17 0.1707 0.934 3633606 CBKinase1_023782 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)c3ccc(C)c(c3)[N+](=O)[O-])n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J03 compound treatment 3887102.0 -39500.0 -0.03 3860032.0 79800.0 0.06 0.0214 0.2982 3633607 CBKinase1_023783 CC(=O)N1CCN(CC1)c2ccc([N+](=O)[O-])c(NCc3cccnc3)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J04 compound treatment 3881316.0 -45300.0 -0.04 3843819.0 63500.0 0.05 0.0088 0.1389 3633608 CBKinase1_023784 O=C(Nc1ccc2OCCOc2c1)C3CC(=O)Nc4ncnn34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J05 mock treatment 3755068.0 -172000.0 -0.14 3751577.0 -28700.0 -0.02 -0.1185 -0.8089 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J06 mock treatment 4116594.0 190000.0 0.16 3659815.0 -120000.0 -0.1 0.0454 0.2432 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J07 compound treatment 3921331.0 -5260.0 0.0 4126459.0 346000.0 0.28 0.192 0.6957 3633609 CBKinase1_023785 Cc1nnc(SCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J08 compound treatment 4125309.0 199000.0 0.17 4325494.0 545000.0 0.43 0.4258 0.9142 3633610 CBKinase1_023786 O=C(CSc1nc(c2ccccc2)c3CCCCCc3n1)N4N=CCC4c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J09 compound treatment 3769296.0 -157000.0 -0.13 3595742.0 -185000.0 -0.15 -0.1978 -0.9987 3633611 CBKinase1_023787 Cn1c(nc2ccccc12)S(=O)(=O)CC(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J10 compound treatment 4213861.0 287000.0 0.24 3849369.0 69100.0 0.06 0.2103 0.8462 3633612 CBKinase1_023788 CCOC(=O)CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J11 compound treatment 3968428.0 41800.0 0.04 4266908.0 487000.0 0.39 0.2992 0.7683 3633613 CBKinase1_023789 CC(=O)c1cccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J12 compound treatment 4298376.0 372000.0 0.31 3941111.0 161000.0 0.13 0.3124 0.9221 3633614 CBKinase1_023790 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)C(=O)NCC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J13 compound treatment 4328336.0 402000.0 0.34 4287031.0 507000.0 0.4 0.5252 0.9962 3633615 CBKinase1_023791 Cc1cc(ccc1Br)N(CC(=O)NC2CCCCCC2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J14 compound treatment 4425225.0 499000.0 0.42 4707202.0 927000.0 0.74 0.8198 0.9643 3633616 CBKinase1_023792 COc1ccc(cc1)c2noc(CCC(=O)Nc3ccc(C)c(C)c3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J15 compound treatment 4262208.0 336000.0 0.28 4554214.0 774000.0 0.62 0.6364 0.9376 3633617 CBKinase1_023793 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)NC4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J16 compound treatment 4273154.0 347000.0 0.29 4573018.0 793000.0 0.63 0.6535 0.9387 3633618 CBKinase1_023794 COc1ccc(OC)c(c1)C2Nc3nc4ccccc4n3C(=C2C(=O)Nc5ccc(C)cc5C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J17 compound treatment 3950303.0 23700.0 0.02 4881001.0 1100000.0 0.88 0.6345 0.723 3633619 CBKinase1_023795 COc1ccc(OC)c(NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3ccc(C)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J18 compound treatment 4816402.0 890000.0 0.75 4740348.0 960000.0 0.77 1.0718 1.0 3633620 CBKinase1_023796 Cc1ccc(cc1)c2cc(no2)C(=O)NCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J19 compound treatment 3610897.0 -316000.0 -0.27 3857647.0 77400.0 0.06 -0.1447 -0.5293 3633621 CBKinase1_023797 COc1ccc(CCNc2c(nn(c3ccccc3)[n+]2[O-])[N+](=O)[O-])cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J20 compound treatment 5217250.0 1290000.0 1.09 5487289.0 1710000.0 1.36 1.7319 0.9939 3633622 CBKinase1_023798 COc1ccc(NC(=O)C2CC(=NO2)c3ccccc3O)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J21 mock treatment 4539634.0 613000.0 0.52 5043603.0 1260000.0 1.01 1.0777 0.952 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J22 mock treatment 4383785.0 457000.0 0.39 4857790.0 1080000.0 0.86 0.88 0.9347 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J23 compound treatment 4099420.0 173000.0 0.15 4370490.0 590000.0 0.47 0.4357 0.8847 3633623 CBKinase1_023799 CCOc1ccc(NC(=O)Cn2ccc(n2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 J24 compound treatment 3964588.0 38000.0 0.03 4427209.0 647000.0 0.52 0.3873 0.7496 3633624 CBKinase1_023800 FC(F)(F)c1cccc(c1)n2c(CSc3ccccn3)nc4ccccc4c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K01 compound treatment 1413951.0 -2510000.0 -2.12 2107656.0 -1670000.0 -1.33 -2.4413 -0.975 3633625 CBKinase1_023801 COc1cccc(NC(=O)CSc2nc(N)c(c3ccccc3)c(=O)[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K02 compound treatment 3304223.0 -622000.0 -0.52 3564515.0 -216000.0 -0.17 -0.4928 -0.8921 3633626 CBKinase1_023802 [O-][N+](=O)c1ccc(NCCNS(=O)(=O)c2ccc(Br)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K03 compound treatment 3312682.0 -614000.0 -0.52 3316583.0 -464000.0 -0.37 -0.6275 -0.9863 3633627 CBKinase1_023803 Cc1cc2c(=O)n(Cc3ccco3)c(SCC(=O)N4CCCc5ccccc45)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K04 compound treatment 4082631.0 156000.0 0.13 4397963.0 618000.0 0.49 0.4412 0.8657 3633628 CBKinase1_023804 Cn1c(COc2ccccc2)nnc1SCc3nc4ccccc4c(=O)[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K05 compound treatment 4116128.0 190000.0 0.16 3777908.0 -2370.0 0.0 0.1117 0.6987 3633629 CBKinase1_023805 Oc1cc(Cl)ccc1NC(=O)CSc2nc3ccccc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K06 compound treatment 4330337.0 404000.0 0.34 3730924.0 -49400.0 -0.04 0.213 0.6213 3633630 CBKinase1_023806 CCN(CC(=O)Nc1ccc(F)cc1F)S(=O)(=O)c2ccc3ccccc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K07 mock treatment 4447277.0 521000.0 0.44 3874584.0 94300.0 0.08 0.3637 0.8163 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K08 mock treatment 3652345.0 -274000.0 -0.23 3774271.0 -6000.0 0.0 -0.167 -0.7216 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K09 compound treatment 3043640.0 -883000.0 -0.74 4011749.0 231000.0 0.18 -0.3962 -0.5163 3633631 CBKinase1_023807 Clc1ccc(cc1)C(=O)c2ccc(CSc3nnc(o3)c4ccccc4)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K10 compound treatment 3117900.0 -809000.0 -0.68 4096103.0 316000.0 0.25 -0.3043 -0.4186 3633632 CBKinase1_023808 CC(=O)c1ccc(NC(=O)CSc2nc(O)c(c3ccccc3)c(=O)[nH]2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K11 compound treatment 4307929.0 381000.0 0.32 4527377.0 747000.0 0.6 0.6485 0.9582 3633633 CBKinase1_023809 [O-][N+](=O)c1cnn(CC(=O)Nc2ccc(F)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K12 compound treatment 4621464.0 695000.0 0.59 3796533.0 16300.0 0.01 0.4236 0.7226 3633634 CBKinase1_023810 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K13 compound treatment 3936970.0 10400.0 0.01 4153487.0 373000.0 0.3 0.2165 0.7276 3633635 CBKinase1_023811 CCOC(=O)c1c(NC(=O)c2ccc(NS(=O)(=O)C)cc2)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K14 compound treatment 4154601.0 228000.0 0.19 3729741.0 -50500.0 -0.04 0.1075 0.5472 3633636 CBKinase1_023812 COc1ccc2[nH]cc(CCNC(=O)Nc3ccccc3)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K15 mock treatment 4343649.0 417000.0 0.35 3542941.0 -237000.0 -0.19 0.115 0.2879 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K16 mock treatment 4564979.0 638000.0 0.54 3981773.0 201000.0 0.16 0.4943 0.8797 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K17 compound treatment 3548061.0 -379000.0 -0.32 3444580.0 -336000.0 -0.27 -0.415 -0.9961 3633637 CBKinase1_023813 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K18 compound treatment 4705564.0 779000.0 0.66 3790982.0 10700.0 0.01 0.4706 0.7162 3040641 CBKinase1_023814 CCN(CC)CCn1nc(C)nc1c2ccccc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K19 compound treatment 5168649.0 1240000.0 1.05 5010664.0 1230000.0 0.98 1.4343 0.9995 3633638 CBKinase1_023815 COCCCNC(=O)C(=O)c1cn(C)c2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K20 compound treatment 4386955.0 460000.0 0.39 3463694.0 -317000.0 -0.25 0.0962 0.2076 3633639 CBKinase1_023816 Clc1ccccc1NC(=O)CCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K21 compound treatment 5054548.0 1130000.0 0.95 3168944.0 -611000.0 -0.49 0.3282 0.3071 3633640 CBKinase1_023817 COc1ccc(C)cc1S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K22 compound treatment 4878806.0 952000.0 0.8 3687204.0 -93100.0 -0.07 0.5155 0.6391 3633641 CBKinase1_023818 COc1ccc(cc1Cl)S(=O)(=O)N(CC(=O)Nc2ccc3OCCOc3c2)C4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K23 mock treatment 4815293.0 889000.0 0.75 3400516.0 -380000.0 -0.3 0.316 0.3909 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 K24 mock treatment 2958716.0 -968000.0 -0.82 3637539.0 -143000.0 -0.11 -0.6577 -0.7979 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L01 compound treatment 3150631.0 -776000.0 -0.65 2646815.0 -1130000.0 -0.9 -1.1016 -0.9875 3633642 CBKinase1_023819 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L02 compound treatment 3682198.0 -244000.0 -0.21 2874919.0 -905000.0 -0.72 -0.656 -0.8741 3633643 CBKinase1_023820 [O-][N+](=O)c1ccc(Sc2nc3ccccc3[nH]2)c(c1)C(=O)NCc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L03 compound treatment 3964176.0 37600.0 0.03 2902227.0 -878000.0 -0.7 -0.4724 -0.6744 3633644 CBKinase1_023821 CC(C)(C)NC(=O)CSc1nnc(c2ccccn2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L04 compound treatment 3909513.0 -17100.0 -0.01 3250785.0 -529000.0 -0.42 -0.3086 -0.7308 3633645 CBKinase1_023822 COc1cccc(c1)N2C(=O)C(CC(=O)Nc3ccc(F)cc3)N(C4CCCCC4)C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L05 compound treatment 4302886.0 376000.0 0.32 4213980.0 434000.0 0.35 0.4689 0.9991 3633646 CBKinase1_023823 C(Cn1c(NCc2ccco2)nc3ccccc13)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L06 compound treatment 4079927.0 153000.0 0.13 4062283.0 282000.0 0.22 0.2504 0.9656 3633647 CBKinase1_023824 CC(C)N(Cc1nc(no1)c2cccc(C)c2)C(=O)c3ccc([N+](=O)[O-])c(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L07 mock treatment 4086249.0 160000.0 0.13 4156291.0 376000.0 0.3 0.3072 0.9348 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L08 mock treatment 4455771.0 529000.0 0.45 4232370.0 452000.0 0.36 0.5704 0.9944 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L09 compound treatment 4403113.0 477000.0 0.4 4269709.0 489000.0 0.39 0.5601 0.9999 3633648 CBKinase1_023825 COc1ccc(C)cc1NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L10 compound treatment 3927969.0 1380.0 0.0 3537281.0 -243000.0 -0.19 -0.1361 -0.7028 3633649 CBKinase1_023826 CS(=O)(=O)N1CCN(CC1)c2ccccc2NC(=O)COc3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L11 compound treatment 4096850.0 170000.0 0.14 4343115.0 563000.0 0.45 0.4188 0.889 3633650 CBKinase1_023827 O=c1n(c(SCc2nc(no2)c3cccs3)nc4sc5CCCCc5c14)c6ccccc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L12 compound treatment 4600965.0 674000.0 0.57 4260791.0 481000.0 0.38 0.673 0.9815 3633651 CBKinase1_023828 Cc1ccc(NC(=O)Cn2cc(cn2)[N+](=O)[O-])cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L13 compound treatment 4453615.0 527000.0 0.44 3841951.0 61700.0 0.05 0.3491 0.7805 3633652 CBKinase1_023829 CC(=O)c1cccc(c1)N(CC(=O)Nc2cccnc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L14 compound treatment 4433818.0 507000.0 0.43 4343164.0 563000.0 0.45 0.6198 0.9997 3633653 CBKinase1_023830 O=C(CSc1nc2sc3CCCc3c2c(=O)n1Cc4ccco4)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L15 mock treatment 4214194.0 288000.0 0.24 3980625.0 200000.0 0.16 0.2845 0.9794 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L16 mock treatment 4287232.0 361000.0 0.3 3693937.0 -86300.0 -0.07 0.1664 0.5337 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L17 compound treatment 3778238.0 -148000.0 -0.13 3795172.0 14900.0 0.01 -0.0801 -0.6371 3633654 CBKinase1_023831 O=c1cc(CSc2nc3ccccc3[nH]2)c4ccccc4[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L18 compound treatment 4841079.0 914000.0 0.77 3295055.0 -485000.0 -0.39 0.272 0.3152 3633655 CBKinase1_023832 Cc1c(Br)c(nn1CC(=O)Nc2ccc(C)c(C)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L19 compound treatment 4841229.0 915000.0 0.77 3842025.0 61700.0 0.05 0.5803 0.7507 3633656 CBKinase1_023833 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3ccccc3F)n2c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L20 compound treatment 3820850.0 -106000.0 -0.09 3668235.0 -112000.0 -0.09 -0.1262 -1.0 3633657 CBKinase1_023834 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L21 compound treatment 5541526.0 1610000.0 1.36 3772648.0 -7630.0 -0.01 0.9589 0.7039 3633658 CBKinase1_023835 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)N)nnc1c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L22 compound treatment 4772113.0 846000.0 0.71 5018209.0 1240000.0 0.99 1.202 0.9873 3633659 CBKinase1_023836 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCc3ccccn3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L23 mock treatment 5013291.0 1090000.0 0.92 4426071.0 646000.0 0.51 1.0121 0.9628 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 L24 mock treatment 3883973.0 -42600.0 -0.04 3307119.0 -473000.0 -0.38 -0.2921 -0.771 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M01 compound treatment 3360258.0 -566000.0 -0.48 3231261.0 -549000.0 -0.44 -0.6472 -0.999 3633660 CBKinase1_023837 CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)CSc2nc3ccccc3s2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M02 compound treatment 3652326.0 -274000.0 -0.23 3584580.0 -196000.0 -0.16 -0.2739 -0.9816 1543133 CBKinase1_023838 O=C(NCc1ccco1)c2cnn3cccnc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M03 compound treatment 3676989.0 -250000.0 -0.21 3070219.0 -710000.0 -0.57 -0.5491 -0.9093 3633661 CBKinase1_023839 O=C(CSc1nc2sc3CCCc3c2c(=O)n1Cc4ccco4)N5CCc6ccccc56 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M04 compound treatment 3494415.0 -432000.0 -0.36 4556871.0 777000.0 0.62 0.1799 0.2505 3633662 CBKinase1_023840 CN(C(=O)C1CCCN1S(=O)(=O)c2ccccc2)c3c(C)n(C)n(c4ccccc4)c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M05 compound treatment 4666899.0 740000.0 0.62 3822400.0 42100.0 0.03 0.4653 0.7441 3633663 CBKinase1_023841 COc1cccc(c1)c2cc(n3nc(cc3n2)C(=O)Nc4c(C#N)cnn4C)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M06 compound treatment 5053117.0 1130000.0 0.95 4605645.0 825000.0 0.66 1.1371 0.9839 3633664 CBKinase1_023842 CC(CO)(CO)NC(=O)NC1CCCCC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M07 compound treatment 3879665.0 -46900.0 -0.04 4458879.0 679000.0 0.54 0.3545 0.6536 3633665 CBKinase1_023843 CCn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4ccccc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M08 compound treatment 4093304.0 167000.0 0.14 4390511.0 610000.0 0.49 0.4434 0.8757 3633666 CBKinase1_023844 Clc1ccccc1C2=NOC(C2)C(=O)NCCCn3ccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M09 mock treatment 4879315.0 953000.0 0.8 3991699.0 211000.0 0.17 0.6874 0.8372 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M10 mock treatment 5055791.0 1130000.0 0.95 4047431.0 267000.0 0.21 0.8241 0.8443 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M11 compound treatment 3809213.0 -117000.0 -0.1 4285421.0 505000.0 0.4 0.2147 0.5178 3633667 CBKinase1_023845 COc1cccc(OCC(=O)Nc2ccc(cc2)c3nc4ccccc4o3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M12 compound treatment 4792953.0 866000.0 0.73 3610694.0 -170000.0 -0.14 0.4212 0.5667 3633668 CBKinase1_023846 O=C(CSc1nc2sc3CCCc3c2c(=O)n1Cc4ccco4)N5CCCc6ccccc56 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M13 mock treatment 4342219.0 416000.0 0.35 4263831.0 484000.0 0.39 0.5204 0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M14 mock treatment 4817300.0 891000.0 0.75 4348425.0 568000.0 0.45 0.8515 0.9706 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M15 compound treatment 4444219.0 518000.0 0.44 4838186.0 1060000.0 0.84 0.905 0.9531 3633669 CBKinase1_023847 Clc1ccc(cc1)c2noc(CCC(=O)NCC3CCCO3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M16 compound treatment 4316362.0 390000.0 0.33 4107752.0 327000.0 0.26 0.417 0.9935 3633670 CBKinase1_023848 Cc1nc2ncnn2c(O)c1NS(=O)(=O)c3ccc4CCCCc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M17 compound treatment 4878790.0 952000.0 0.8 4580519.0 800000.0 0.64 1.0189 0.9935 3633671 CBKinase1_023849 COC(=O)C1=C(C)Nc2ncnn2C1c3ccc(OCC(=O)N4CCOCC4)c(OC)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M18 compound treatment 3681330.0 -245000.0 -0.21 3889153.0 109000.0 0.09 -0.0849 -0.3785 3633672 CBKinase1_023850 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3cc4cccc(OC)c4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M19 compound treatment 5494632.0 1570000.0 1.32 5071950.0 1290000.0 1.03 1.6632 0.9923 3633673 CBKinase1_023851 NC(=O)C(Cc1ccccc1)NS(=O)(=O)c2ccc3oc4ccccc4c3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M20 compound treatment 5336844.0 1410000.0 1.19 5054341.0 1270000.0 1.02 1.5592 0.9969 3633674 CBKinase1_023852 CC1(C)Cc2nc3sc4c(SCC(=O)Nc5ccc(Cl)cc5)ncnc4c3cc2CO1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M21 compound treatment 5306811.0 1380000.0 1.16 4672902.0 893000.0 0.71 1.3263 0.9721 3633675 CBKinase1_023853 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4ccccc4O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M22 compound treatment 5530734.0 1600000.0 1.35 5224240.0 1440000.0 1.15 1.7706 0.9968 3633676 CBKinase1_023854 COc1ccc(Cl)cc1NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M23 compound treatment 4741445.0 815000.0 0.69 4540533.0 760000.0 0.61 0.9145 0.998 3633677 CBKinase1_023855 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cc(ccc2Cl)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 M24 compound treatment 3585307.0 -341000.0 -0.29 3359627.0 -421000.0 -0.34 -0.4406 -0.9971 3633678 CBKinase1_023856 CCOc1ccc(Nc2nc(CSc3nc4ccccc4c(=O)n3c5ccccc5)cs2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N01 compound treatment 3438750.0 -488000.0 -0.41 4101164.0 321000.0 0.26 -0.1101 -0.2273 3633679 CBKinase1_023857 NC(=O)C1(CCN(CC(=O)Nc2ccc(Br)cc2)CC1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N02 compound treatment 3614624.0 -312000.0 -0.26 3634539.0 -146000.0 -0.12 -0.2682 -0.9324 3633680 CBKinase1_023858 OC(=O)CCS(=O)(=O)c1nc(cc(n1)C(F)(F)F)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N03 compound treatment 4071728.0 145000.0 0.12 4336925.0 557000.0 0.44 0.4003 0.8697 3633681 CBKinase1_023859 CCn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4cc5cccc(OC)c5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N04 compound treatment 4297907.0 371000.0 0.31 4651971.0 872000.0 0.69 0.7128 0.9352 3633682 CBKinase1_023860 Cc1cc(C)cc(NC(=O)C2CC(=O)n3ncnc3N2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N05 compound treatment 4323586.0 397000.0 0.33 4389415.0 609000.0 0.49 0.5801 0.9836 3633683 CBKinase1_023861 COC(=O)c1ccc2c(=O)n(CCCN3CCOCC3)c(=S)[nH]c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N06 compound treatment 3630899.0 -296000.0 -0.25 3333827.0 -446000.0 -0.36 -0.428 -0.9849 3633684 CBKinase1_023862 Cc1cc(NC(=O)NCCCN2CCN(CC2)C3CCCCC3)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N07 compound treatment 4650476.0 724000.0 0.61 4373049.0 593000.0 0.47 0.7658 0.992 3633685 CBKinase1_023863 CC1CCN(CC(=O)Nc2sc3CCCCc3c2C(=O)Nc4ccccc4)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N08 compound treatment 4877804.0 951000.0 0.8 4644568.0 864000.0 0.69 1.0545 0.9971 3633686 CBKinase1_023864 Cc1c(NC(=O)Cn2nc(c3CCCCc32)C(F)(F)F)c(=O)n(c4ccccc4)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N09 mock treatment 4583057.0 656000.0 0.55 4215570.0 435000.0 0.35 0.6369 0.9746 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N10 mock treatment 4579446.0 653000.0 0.55 4069424.0 289000.0 0.23 0.5524 0.9253 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N11 compound treatment 4530323.0 604000.0 0.51 4607725.0 827000.0 0.66 0.8264 0.9918 3633687 CBKinase1_023865 Fc1ccc(NC(=O)COc2ccc(cc2)S(=O)(=O)N3CCOCC3)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N12 compound treatment 4675165.0 749000.0 0.63 4239337.0 459000.0 0.37 0.7052 0.9663 3633688 CBKinase1_023866 Cc1c(NC(=O)CSc2nnnn2c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N13 mock treatment 4814029.0 887000.0 0.75 4432993.0 653000.0 0.52 0.8972 0.9842 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N14 mock treatment 5000693.0 1070000.0 0.91 4935292.0 1160000.0 0.92 1.2916 1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N15 compound treatment 4641521.0 715000.0 0.6 4831093.0 1050000.0 0.84 1.0187 0.987 3633689 CBKinase1_023867 CC(Sc1ncnc2sc(cc12)c3ccccc3)C(=O)Nc4ccccc4C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N16 compound treatment 4790141.0 864000.0 0.73 5087530.0 1310000.0 1.04 1.2518 0.9847 3633690 CBKinase1_023868 CC(Sc1ncnc2sc3CCCCc3c12)C(=O)Nc4ccc(Br)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N17 compound treatment 4619551.0 693000.0 0.58 4991530.0 1210000.0 0.97 1.096 0.9711 3633691 CBKinase1_023869 Cc1nnc(SCc2ccon2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N18 compound treatment 5028162.0 1100000.0 0.93 4907674.0 1130000.0 0.9 1.2924 0.9999 3633692 CBKinase1_023870 Nc1nnc(SCc2cccnc2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N19 compound treatment 5603171.0 1680000.0 1.41 5297529.0 1520000.0 1.21 1.8551 0.997 3633693 CBKinase1_023871 Fc1ccccc1c2nnc(SCC(=O)Nc3ccc4cn[nH]c4c3)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N20 compound treatment 3478378.0 -448000.0 -0.38 4972202.0 1190000.0 0.95 0.4044 0.3955 3633694 CBKinase1_023872 O=C(CCNc1ccc(Oc2ccccc2)cc1)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N21 compound treatment 4232792.0 306000.0 0.26 5345897.0 1570000.0 1.25 1.065 0.8357 3633695 CBKinase1_023873 CC(C)OC(=O)CSc1nnc(c2ccncc2)n1c3ccc(C)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N22 compound treatment 4675818.0 749000.0 0.63 4557676.0 777000.0 0.62 0.885 1.0 3633696 CBKinase1_023874 CCOc1ccc2nc(NCc3cc(OC)c(OC)cc3OC)sc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N23 compound treatment 4391159.0 465000.0 0.39 4452850.0 673000.0 0.54 0.6562 0.9881 3633697 CBKinase1_023875 COC(=O)c1cccc(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 N24 compound treatment 4690084.0 763000.0 0.64 4234936.0 455000.0 0.36 0.7116 0.963 3633698 CBKinase1_023876 COc1ccc(cc1)c2nnc(SCC(=O)c3ccc(C)o3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O01 compound treatment 3548658.0 -378000.0 -0.32 3389793.0 -390000.0 -0.31 -0.4455 -0.9999 3633699 CBKinase1_023877 COc1cc(Cc2nccc3cc(OC)c(OC)cc23)c(NC(=O)c4cc(F)c(F)cc4Cl)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O02 compound treatment 3414025.0 -513000.0 -0.43 5400930.0 1620000.0 1.29 0.6077 0.4461 3633700 CBKinase1_023878 COc1cc(NC(=O)COC(=O)C)cc(OC)c1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O03 compound treatment 4516897.0 590000.0 0.5 4281811.0 502000.0 0.4 0.6347 0.9941 1430592 CBKinase1_023879 COc1ccc(c2ccccc12)S(=O)(=O)N(C)CC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O04 compound treatment 4082614.0 156000.0 0.13 5262227.0 1480000.0 1.18 0.9283 0.7811 3633701 CBKinase1_023880 COc1ccc(cc1)c2noc(CSc3nnc(C)n3c4ccccc4)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O05 compound treatment 4479788.0 553000.0 0.47 4543855.0 764000.0 0.61 0.7603 0.9914 3633702 CBKinase1_023881 COc1ccc(OC)c(NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O06 compound treatment 4015382.0 88800.0 0.07 4951884.0 1170000.0 0.93 0.7133 0.7614 3633703 CBKinase1_023882 Cc1nc2ncnn2c(O)c1NS(=O)(=O)c3ccc(cc3)C4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O07 compound treatment 5002007.0 1080000.0 0.91 4693831.0 914000.0 0.73 1.1563 0.9941 3633704 CBKinase1_023883 CN(CC(=O)O)S(=O)(=O)c1cccc2cccc(Cl)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O08 compound treatment 4745715.0 819000.0 0.69 5023910.0 1240000.0 0.99 1.1895 0.9844 3633705 CBKinase1_023884 COc1ccc(cc1)S(=O)(=O)Nc2c(C)nc3ncnn3c2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O09 compound treatment 4963049.0 1040000.0 0.87 5041100.0 1260000.0 1.0 1.3288 0.9976 3633706 CBKinase1_023885 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)NCc3cccnc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O10 compound treatment 4426884.0 500000.0 0.42 4198315.0 418000.0 0.33 0.534 0.9932 3633707 CBKinase1_023886 COc1ccc(cc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O11 mock treatment 4793877.0 867000.0 0.73 4775801.0 996000.0 0.79 1.0784 0.9992 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O12 mock treatment 5631356.0 1700000.0 1.44 4953316.0 1170000.0 0.93 1.6779 0.9783 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O13 compound treatment 5265853.0 1340000.0 1.13 5178343.0 1400000.0 1.11 1.5867 1.0 3633708 CBKinase1_023887 COc1c(C)cccc1C(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4ccco4)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O14 compound treatment 5143680.0 1220000.0 1.03 5660912.0 1880000.0 1.5 1.7858 0.983 3633709 CBKinase1_023888 C(CN1CCOCC1)Nc2ncnc3oc(c(c4ccccc4)c23)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O15 compound treatment 5080797.0 1150000.0 0.97 5524095.0 1740000.0 1.39 1.6712 0.9848 3633710 CBKinase1_023889 CN(CC(=O)O)S(=O)(=O)c1ccc(F)c2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O16 compound treatment 5632155.0 1710000.0 1.44 5512363.0 1730000.0 1.38 1.9935 0.9998 3633711 CBKinase1_023890 CCOc1ccc(NC(=O)Cn2cnc3scc(c4ccc5ccccc5c4)c3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O17 compound treatment 5918245.0 1990000.0 1.68 5687547.0 1910000.0 1.52 2.2628 0.9988 3633712 CBKinase1_023891 Clc1ccc(NC(=O)CCc2nc(no2)c3ccccc3Cl)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O18 compound treatment 4954541.0 1030000.0 0.87 5502423.0 1720000.0 1.37 1.5837 0.9755 3633713 CBKinase1_023892 CC(C)(C)C1CCc2c(C#N)c(NC(=O)CSc3nnnn3c4ccccc4)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O19 compound treatment 6008508.0 2080000.0 1.76 6403082.0 2620000.0 2.09 2.7199 0.9962 3633714 CBKinase1_023893 Cc1ccc(cc1)c2nc(c(SCC(=O)N)o2)S(=O)(=O)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O20 compound treatment 6233580.0 2310000.0 1.95 5779772.0 2000000.0 1.59 2.5029 0.9951 1978488 CBKinase1_023894 Cc1nnc(SCC(=O)Nc2ccc(OC(F)(F)F)cc2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O21 compound treatment 4469671.0 543000.0 0.46 5892408.0 2110000.0 1.68 1.5143 0.868 3633715 CBKinase1_023895 Clc1ccccc1C2=NOC(C2)C(=O)NCc3cccnc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O22 compound treatment 4408714.0 482000.0 0.41 5246260.0 1470000.0 1.17 1.1138 0.9002 3633716 CBKinase1_023896 CCOC(=O)Nc1ccc(OCc2nnc3c4ccccc4c(C)nn23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O23 compound treatment 4594225.0 668000.0 0.56 4993289.0 1210000.0 0.97 1.0819 0.9669 3633717 CBKinase1_023897 CCOC(=O)c1c(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCOCC3)sc4CCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 O24 compound treatment 4009660.0 83100.0 0.07 3912204.0 132000.0 0.11 0.1239 0.9805 3633718 CBKinase1_023898 CCOC(=O)Nc1cccc(NC(=O)CC2c3ccccc3Oc4ccccc24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P01 compound treatment 2485446.0 -1440000.0 -1.22 2714963.0 -1070000.0 -0.85 -1.46 -0.9846 3633719 CBKinase1_023899 Oc1cc(OCC(=O)c2cccc(c2)[N+](=O)[O-])cc3oc4ccccc4c(=O)c13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P02 compound treatment 3420113.0 -506000.0 -0.43 3653181.0 -127000.0 -0.1 -0.3737 -0.8512 3633720 CBKinase1_023900 OC(=O)c1cccc(NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P03 compound treatment 4065556.0 139000.0 0.12 3016437.0 -764000.0 -0.61 -0.3476 -0.5607 3633721 CBKinase1_023901 COc1ccccc1C(=O)Nc2c(C)nc(O)nc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P04 compound treatment 3740492.0 -186000.0 -0.16 3778669.0 -1610.0 0.0 -0.1119 -0.7129 3633722 CBKinase1_023902 [O-][N+](=O)c1ccn(CC(=O)NCC2CCCO2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P05 compound treatment 4059248.0 133000.0 0.11 4302436.0 522000.0 0.42 0.3734 0.8665 1494644 CBKinase1_023903 COc1ccc(CCNc2ccncn2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P06 compound treatment 4061056.0 134000.0 0.11 3176743.0 -604000.0 -0.48 -0.2599 -0.526 3633723 CBKinase1_023904 CCN(CC(=O)Nc1ccc(cc1)C(=O)N)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P07 compound treatment 4130692.0 204000.0 0.17 3650996.0 -129000.0 -0.1 0.0489 0.2436 3633724 CBKinase1_023905 Cn1c(=O)n(C)c2nc(SCC(=O)NC(C)(C)C)n(Cc3ccccc3F)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P08 compound treatment 4111788.0 185000.0 0.16 3827028.0 46800.0 0.04 0.1368 0.8519 3633725 CBKinase1_023906 [O-][N+](=O)c1cnn(CC(=O)n2cccn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P09 compound treatment 3628369.0 -298000.0 -0.25 3288096.0 -492000.0 -0.39 -0.4553 -0.9769 3633726 CBKinase1_023907 NC(=O)C1(CCN(CC(=O)Nc2ccc(Cl)cc2)CC1)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P10 compound treatment 1974224.0 -1950000.0 -1.65 1865594.0 -1910000.0 -1.53 -2.2436 -0.9993 3633727 CBKinase1_023908 COc1ccc(C)cc1NC(=O)NCCCN2CCN(CC2)c3ccccc3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P11 mock treatment 3663935.0 -263000.0 -0.22 3493529.0 -287000.0 -0.23 -0.3183 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P12 mock treatment 4286480.0 360000.0 0.3 3784386.0 4110.0 0.0 0.217 0.7147 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P13 compound treatment 4439480.0 513000.0 0.43 4227359.0 447000.0 0.36 0.5579 0.9954 3633728 CBKinase1_023909 Cc1ccc(NC(=O)Cn2ccc(n2)[N+](=O)[O-])cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P14 compound treatment 4635239.0 709000.0 0.6 4115695.0 335000.0 0.27 0.6117 0.9342 3633729 CBKinase1_023910 CCc1cc(c2n[nH]c(C)c2c3nc(C)cs3)c(O)cc1OCc4ccc(cc4)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P15 compound treatment 4208746.0 282000.0 0.24 4463630.0 683000.0 0.54 0.5534 0.9311 3633730 CBKinase1_023911 [O-][N+](=O)c1ccc(cc1NCc2ccco2)N3CCN(CC3)S(=O)(=O)c4ccc(Cl)s4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P16 compound treatment 4467367.0 541000.0 0.46 4778623.0 998000.0 0.8 0.8852 0.9651 3633731 CBKinase1_023912 O=C(Nc1cccc2ccccc12)C3CCCN3S(=O)(=O)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P17 compound treatment 4576137.0 650000.0 0.55 4154522.0 374000.0 0.3 0.5983 0.9591 3633732 CBKinase1_023913 COc1cccc(OC)c1C(=O)Nc2ccc(Cl)c(c2)c3nc4ncccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P18 compound treatment 4797492.0 871000.0 0.73 4489139.0 709000.0 0.56 0.919 0.9916 3633733 CBKinase1_023914 COCCNC(=O)c1ccccc1c2nc(no2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P19 compound treatment 4933247.0 1010000.0 0.85 4871544.0 1090000.0 0.87 1.2154 0.9999 3633734 CBKinase1_023915 Fc1ccccc1c2nnc(SCc3ccc(Br)cc3)n2Cc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P20 compound treatment 4924078.0 997000.0 0.84 5174299.0 1390000.0 1.11 1.3806 0.9906 3633735 CBKinase1_023916 COc1ccccc1CC(=O)Nc2ccc(cc2)c3nnc(o3)c4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P21 compound treatment 4882776.0 956000.0 0.81 4744887.0 965000.0 0.77 1.114 0.9997 1744275 CBKinase1_023917 COc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3c4ccccc4)nnc2c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P22 compound treatment 4915625.0 989000.0 0.83 4820837.0 1040000.0 0.83 1.1764 1.0 3633736 CBKinase1_023918 C(Cc1ccccc1)c2nn3c(Cn4cnc5ccccc45)nnc3s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P23 compound treatment 4173964.0 247000.0 0.21 4654886.0 875000.0 0.7 0.6405 0.8802 3041049 CBKinase1_023919 C(Sc1nc2ccccc2[nH]1)c3cc(no3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2398 P24 compound treatment 3242475.0 -684000.0 -0.58 3532877.0 -247000.0 -0.2 -0.5475 -0.8978 3633737 CBKinase1_023920 Cc1nn(CC(=O)Nc2ccc(C)c(Cl)c2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A01 compound treatment 3449982.0 -292000.0 -0.25 2833282.0 -842000.0 -0.67 -0.6489 -0.9075 3633738 CBKinase1_023921 CSc1nsc(SCc2cnc(C)nc2N)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A02 compound treatment 3626337.0 -116000.0 -0.1 2462642.0 -1210000.0 -0.97 -0.7526 -0.7746 3633739 CBKinase1_023922 CCOC(=O)c1ccc(NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A03 compound treatment 3122381.0 -620000.0 -0.52 3146506.0 -529000.0 -0.42 -0.6677 -0.9943 3633740 CBKinase1_023923 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)c3ccccc3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A04 compound treatment 3409356.0 -333000.0 -0.28 3430057.0 -245000.0 -0.2 -0.3368 -0.9844 3633741 CBKinase1_023924 [O-][N+](=O)c1ccn(CC(=O)NCc2cccs2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A05 compound treatment 3689243.0 -52900.0 -0.04 3013516.0 -662000.0 -0.53 -0.4046 -0.7642 3633742 CBKinase1_023925 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)NCCCn3ccnc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A06 compound treatment 3416476.0 -326000.0 -0.27 4325806.0 650000.0 0.52 0.1723 0.2937 3633743 CBKinase1_023926 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cnn3cccnc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A07 compound treatment 3868923.0 127000.0 0.11 2751669.0 -924000.0 -0.74 -0.445 -0.5981 3633744 CBKinase1_023927 COc1cc(Cc2nccc3cc(OC)c(OC)cc23)c(NC(=O)c4cccs4)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A08 compound treatment 2727420.0 -1010000.0 -0.86 2692028.0 -983000.0 -0.78 -1.1594 -0.999 3633745 CBKinase1_023928 CC1(C)Cc2c(CO1)c(nc3sc4c(SCc5nc6ccccc6[nH]5)ncnc4c23)N7CCOCC7 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A09 compound treatment 3782957.0 40800.0 0.03 3697060.0 21700.0 0.02 0.0366 0.9493 3633746 CBKinase1_023929 COc1ccc(NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A10 compound treatment 3560781.0 -181000.0 -0.15 3716010.0 40600.0 0.03 -0.0853 -0.5453 3633747 CBKinase1_023930 Cc1cc(nn1CC(=O)Nc2ncccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A11 compound treatment 3444026.0 -298000.0 -0.25 3095861.0 -580000.0 -0.46 -0.5044 -0.9591 3633748 CBKinase1_023931 CS(=O)(=O)N(CC(=O)NC1CC2CCC1C2)c3cc(Cl)c(Cl)cc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A12 compound treatment 3843185.0 101000.0 0.09 3250821.0 -425000.0 -0.34 -0.179 -0.513 3633749 CBKinase1_023932 CCOc1cc(ccc1F)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A13 mock treatment 3553316.0 -189000.0 -0.16 3437659.0 -238000.0 -0.19 -0.2466 -0.9963 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A14 mock treatment 3677560.0 -64600.0 -0.05 3282436.0 -393000.0 -0.31 -0.26 -0.8179 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A15 compound treatment 3708868.0 -33300.0 -0.03 3562851.0 -113000.0 -0.09 -0.0833 -0.8861 3633750 CBKinase1_023933 CC(=O)Nc1ccc2n3CCN(Cc4ccco4)Cc3nc2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A16 compound treatment 3925124.0 183000.0 0.15 4013748.0 338000.0 0.27 0.2998 0.9649 3633751 CBKinase1_023934 COC(=O)c1cc(NC(=O)CC2SCCNC2=O)cc(c1)C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A17 compound treatment 3844006.0 102000.0 0.09 3221525.0 -454000.0 -0.36 -0.195 -0.5246 3633752 CBKinase1_023935 O=C(COc1ccccc1)Nc2ncc3C(=O)CCCc3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A18 compound treatment 3901065.0 159000.0 0.13 3367183.0 -308000.0 -0.25 -0.0789 -0.282 3633753 CBKinase1_023936 CCOC(=O)c1c(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A19 compound treatment 4147357.0 405000.0 0.34 3574306.0 -101000.0 -0.08 0.1847 0.526 3633754 CBKinase1_023937 [O-][N+](=O)c1ccn(CC(=O)Nc2ccc(C#N)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A20 compound treatment 4016278.0 274000.0 0.23 4047582.0 372000.0 0.3 0.3733 0.9924 3633755 CBKinase1_023938 Cc1nc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)nc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A21 compound treatment 4040455.0 298000.0 0.25 4079626.0 404000.0 0.32 0.4057 0.9925 3633756 CBKinase1_023939 C(Oc1ccc(Oc2nc(nc(n2)N3CCOCC3)N4CCCCC4)nn1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A22 compound treatment 4063388.0 321000.0 0.27 3808942.0 134000.0 0.11 0.2669 0.9167 3633757 CBKinase1_023940 CCOc1ccccc1NC(=O)C2CC(=O)n3ncnc3N2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A23 compound treatment 3648085.0 -94100.0 -0.08 3333954.0 -341000.0 -0.27 -0.2485 -0.8768 3633758 CBKinase1_023941 COc1ccc(cc1NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 A24 compound treatment 3202306.0 -540000.0 -0.46 3164806.0 -511000.0 -0.41 -0.6097 -0.9984 3633759 CBKinase1_023942 [O-][N+](=O)c1cnn(CCCC(=O)Nc2cc(F)ccc2F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B01 compound treatment 2606154.0 -1140000.0 -0.96 2789330.0 -886000.0 -0.71 -1.1769 -0.9887 3633760 CBKinase1_023943 COc1cc(ccc1NC(=O)CSc2nc(C)cc(n2)c3ccc(Cl)cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B02 compound treatment 3622581.0 -120000.0 -0.1 3241025.0 -434000.0 -0.35 -0.3161 -0.8767 3633761 CBKinase1_023944 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B03 compound treatment 3562336.0 -180000.0 -0.15 2889663.0 -786000.0 -0.63 -0.5501 -0.8537 3633762 CBKinase1_023945 Clc1ccc(c2nnc(SCC(=O)Nc3ccc(I)cc3)[nH]2)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B04 compound treatment 3499028.0 -243000.0 -0.21 3716558.0 41200.0 0.03 -0.1218 -0.5864 3633763 CBKinase1_023946 CC(=O)c1cccc(c1)N(CC(=O)N2CCN(CC2)c3ccccc3F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B05 compound treatment 4685157.0 943000.0 0.8 2874485.0 -801000.0 -0.64 0.1111 0.1089 3633764 CBKinase1_023947 COC(=O)c1ccc(Cl)c(NC(=O)CN2CCOCC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B06 compound treatment 4678071.0 936000.0 0.79 3617320.0 -58000.0 -0.05 0.5255 0.6645 3633765 CBKinase1_023948 Cc1ccc(C)c(NC(=O)c2ccc(OCC(=O)Nc3cccc(Cl)c3)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B07 compound treatment 3303411.0 -439000.0 -0.37 3148644.0 -527000.0 -0.42 -0.5586 -0.998 3633766 CBKinase1_023949 COc1ccc(cc1OC)C(=O)NCC(=O)Nc2ccc(C)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B08 compound treatment 3994729.0 253000.0 0.21 3743619.0 68300.0 0.05 0.1891 0.8601 3633767 CBKinase1_023950 O=C1COc2ccc(cc2N1)S(=O)(=O)NCCOc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B09 compound treatment 3784008.0 41800.0 0.04 3568484.0 -107000.0 -0.09 -0.0353 -0.3826 3633768 CBKinase1_023951 COc1ccc(NC(=O)CN2CCOCC2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B10 compound treatment 4132335.0 390000.0 0.33 3455291.0 -220000.0 -0.18 0.1087 0.2914 3633769 CBKinase1_023952 Cc1ccc(cc1)c2nnc(SC(CC(=O)O)c3ccccc3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B11 compound treatment 4162684.0 421000.0 0.35 3424545.0 -251000.0 -0.2 0.1095 0.2688 3633770 CBKinase1_023953 Cc1cc(OCC(=O)NCc2ccco2)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B12 compound treatment 4377001.0 635000.0 0.54 4092412.0 417000.0 0.33 0.6137 0.9737 3633771 CBKinase1_023954 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B13 mock treatment 4334123.0 592000.0 0.5 4045551.0 370000.0 0.3 0.5617 0.9685 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B14 mock treatment 4344353.0 602000.0 0.51 3927964.0 253000.0 0.2 0.5015 0.9179 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B15 compound treatment 4548561.0 806000.0 0.68 4053615.0 378000.0 0.3 0.6941 0.933 3633772 CBKinase1_023955 Cc1nnc(SCC(=O)Nc2ccc(Cl)c(C)c2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B16 compound treatment 4048677.0 307000.0 0.26 4079334.0 404000.0 0.32 0.4105 0.9941 3633773 CBKinase1_023956 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B17 compound treatment 4043829.0 302000.0 0.25 3460518.0 -215000.0 -0.17 0.0588 0.1918 3633774 CBKinase1_023957 Cn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B18 compound treatment 4482157.0 740000.0 0.62 3891720.0 216000.0 0.17 0.5633 0.8699 3633775 CBKinase1_023958 COc1cc(ccc1OCC(=O)N2CCOCC2)C3C4=C(CC(C)(C)CC4=O)Nc5ncnn35 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B19 compound treatment 4722175.0 980000.0 0.83 4070672.0 395000.0 0.32 0.8073 0.9126 3633776 CBKinase1_023959 CS(=O)(=O)N(CC(=O)Nc1cccc(Br)c1)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B20 compound treatment 4711868.0 970000.0 0.82 4219951.0 545000.0 0.43 0.8853 0.9561 3633777 CBKinase1_023960 O=C(NCc1ccccn1)C2CCCN(C2)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B21 compound treatment 4145242.0 403000.0 0.34 4362881.0 688000.0 0.55 0.6279 0.9736 3633778 CBKinase1_023961 Cc1cc(=O)n2c3ccccc3n(CC(O)CN4CCN(CCO)CC4)c2c1C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B22 compound treatment 4951539.0 1210000.0 1.02 4394749.0 719000.0 0.57 1.1268 0.9629 3633779 CBKinase1_023962 OC1(CC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)N(Cc3ccc(Cl)c(Cl)c3)c4ccccc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B23 compound treatment 4248844.0 507000.0 0.43 4264603.0 589000.0 0.47 0.6343 0.9989 3633780 CBKinase1_023963 COc1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 B24 compound treatment 3531142.0 -211000.0 -0.18 3382091.0 -293000.0 -0.23 -0.2912 -0.991 3633781 CBKinase1_023964 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C01 compound treatment 3026440.0 -716000.0 -0.6 2618461.0 -1060000.0 -0.84 -1.0226 -0.9867 3633782 CBKinase1_023965 COC(=O)COc1ccc(NC(=O)c2ccc([N+](=O)[O-])c(C)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C02 compound treatment 2952144.0 -790000.0 -0.67 2758144.0 -917000.0 -0.73 -0.9881 -0.9989 3633783 CBKinase1_023966 CCn1c(SCC(=O)Nc2cc(F)ccc2C)nnc1c3ccccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C03 compound treatment 3322144.0 -420000.0 -0.35 3361870.0 -313000.0 -0.25 -0.4272 -0.9854 3633784 CBKinase1_023967 Cc1nc(O)nc(O)c1NS(=O)(=O)c2ccc3CCCCc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C04 compound treatment 3438651.0 -304000.0 -0.26 3017963.0 -657000.0 -0.52 -0.5515 -0.9457 3633785 CBKinase1_023968 Cc1cccc(OCC(=O)Nc2ccc(Cl)c(c2)c3nc4ccc(C)cc4o3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C05 compound treatment 3841035.0 98900.0 0.08 3327990.0 -347000.0 -0.28 -0.1368 -0.4731 3633786 CBKinase1_023969 COc1ccc(NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C06 compound treatment 3923327.0 181000.0 0.15 3114424.0 -561000.0 -0.45 -0.2081 -0.4404 3633787 CBKinase1_023970 O=C1N(CCCSc2nnc[nH]2)C(=O)c3cccc4cccc1c34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C07 compound treatment 3799890.0 57700.0 0.05 3360704.0 -315000.0 -0.25 -0.1429 -0.5594 3633788 CBKinase1_023971 C(c1nnc2sc(nn12)c3ccccn3)n4cnc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C08 compound treatment 3714984.0 -27200.0 -0.02 3561739.0 -114000.0 -0.09 -0.0803 -0.859 3633789 CBKinase1_023972 COc1ccc(cc1OC)c2nnc(SCCC(=O)O)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C09 compound treatment 3678985.0 -63200.0 -0.05 3336135.0 -339000.0 -0.27 -0.2289 -0.8305 3633790 CBKinase1_023973 COc1ccc(C2NC(=S)NC(=C2C(=O)Nc3cc(OC)c(Cl)cc3OC)C)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C10 compound treatment 4136299.0 394000.0 0.33 3612456.0 -62900.0 -0.05 0.1996 0.5937 3633791 CBKinase1_023974 CCCCn1nnnc1NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C11 mock treatment 4389317.0 647000.0 0.55 3405073.0 -270000.0 -0.22 0.2337 0.3981 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C12 mock treatment 3993533.0 251000.0 0.21 3683730.0 8360.0 0.01 0.1546 0.729 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C13 compound treatment 4000716.0 259000.0 0.22 3737350.0 62000.0 0.05 0.1891 0.8459 3633792 CBKinase1_023975 Cc1cc(NC(=O)c2cnn3c(cc(nc23)c4cccs4)C(F)(F)F)n(n1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C14 compound treatment 4008462.0 266000.0 0.22 3836818.0 161000.0 0.13 0.2498 0.9651 3633793 CBKinase1_023976 COc1cc(OC)c(OC)cc1CNC(C)C(O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C15 mock treatment 3967221.0 225000.0 0.19 3573012.0 -102000.0 -0.08 0.0765 0.3705 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C16 mock treatment 3858630.0 116000.0 0.1 3605867.0 -69500.0 -0.06 0.0303 0.2686 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C17 compound treatment 4174605.0 432000.0 0.36 3704715.0 29300.0 0.02 0.2745 0.7509 3633794 CBKinase1_023977 CCN(CC(=O)Nc1cccc(Cl)c1C)S(=O)(=O)c2ccc(OC)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C18 compound treatment 4207651.0 465000.0 0.39 3421901.0 -253000.0 -0.2 0.1348 0.3052 3633795 CBKinase1_023978 CC(C(=O)Nc1ccc(NC(=O)C)cc1)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C19 compound treatment 4373385.0 631000.0 0.53 4089342.0 414000.0 0.33 0.6098 0.9735 3633796 CBKinase1_023979 Cc1ccc(cc1NC(=O)C(C)(C)Oc2ccc(Cl)cc2)c3nc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C20 compound treatment 3882090.0 140000.0 0.12 4018481.0 343000.0 0.27 0.2768 0.9294 3633797 CBKinase1_023980 OC1(CC(=O)c2ccncc2)C(=O)N(Cc3ccccc3Cl)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C21 compound treatment 4014377.0 272000.0 0.23 3558034.0 -117000.0 -0.09 0.0962 0.3881 3633798 CBKinase1_023981 O=C(CN1CCOCC1)Nc2ccc(cc2)S(=O)(=O)N3CCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C22 compound treatment 4021050.0 279000.0 0.24 3510835.0 -165000.0 -0.13 0.0736 0.2733 3633799 CBKinase1_023982 [O-][N+](=O)c1cnn(CC(=O)n2cc(Br)cn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C23 compound treatment 3845857.0 104000.0 0.09 3273364.0 -402000.0 -0.32 -0.1647 -0.496 3633800 CBKinase1_023983 COc1cc(NC(=O)C(C)Oc2cccc(Cl)c2)c(cc1OC)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 C24 compound treatment 2982882.0 -759000.0 -0.64 3087251.0 -588000.0 -0.47 -0.7843 -0.9882 3633801 CBKinase1_023984 CC(C)OC(=O)C1=C(C)Nc2ncnn2C1c3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D01 compound treatment 2931483.0 -811000.0 -0.68 2741351.0 -934000.0 -0.74 -1.0099 -0.9991 3633802 CBKinase1_023985 CSc1nnc(c(O)n1)c2ccccc2NC(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D02 compound treatment 2770520.0 -972000.0 -0.82 2679228.0 -996000.0 -0.79 -1.141 -0.9999 3633803 CBKinase1_023986 FC(F)(F)c1ccccc1NC(=O)COc2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D03 compound treatment 4060483.0 318000.0 0.27 3057822.0 -618000.0 -0.49 -0.1582 -0.2821 3633804 CBKinase1_023987 FC(F)(F)c1cc(nc(SCC(=O)c2ccc(Br)cc2)n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D04 compound treatment 4131482.0 389000.0 0.33 3590267.0 -85100.0 -0.07 0.1842 0.5495 3633805 CBKinase1_023988 Nc1nnc(SCC(=O)Nc2ccc(Cl)cc2O)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D05 compound treatment 3862455.0 120000.0 0.1 3862555.0 187000.0 0.15 0.1772 0.9823 3633806 CBKinase1_023989 COc1cccc(c1)C(=O)Nc2cccc(OCC(=O)O)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D06 compound treatment 3639586.0 -103000.0 -0.09 3854243.0 179000.0 0.14 0.0396 0.2376 3633807 CBKinase1_023990 Cc1nn(Cc2ccccc2C)c(C)c1NC(=O)C3CC(=NO3)c4cccc(Br)c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D07 compound treatment 4172072.0 430000.0 0.36 3502030.0 -173000.0 -0.14 0.1587 0.409 3633808 CBKinase1_023991 Cc1cc(nc(SCC(=O)Nc2ccccc2C(F)(F)F)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D08 compound treatment 3715429.0 -26700.0 -0.02 3699073.0 23700.0 0.02 -0.0026 -0.0879 3633809 CBKinase1_023992 Fc1ccccc1NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D09 compound treatment 3674885.0 -67300.0 -0.06 3928692.0 253000.0 0.2 0.1026 0.4894 3633810 CBKinase1_023993 Fc1ccccc1C(=O)c2cn(CC(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D10 compound treatment 3787250.0 45100.0 0.04 3931272.0 256000.0 0.2 0.1711 0.8247 3633811 CBKinase1_023994 COc1ccc(cc1OC)c2nnc(SCC(=O)N)n2c3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D11 mock treatment 4026220.0 284000.0 0.24 3982583.0 307000.0 0.24 0.3426 0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D12 mock treatment 4017588.0 275000.0 0.23 3805783.0 130000.0 0.1 0.2378 0.9342 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D13 compound treatment 3837503.0 95300.0 0.08 4112244.0 437000.0 0.35 0.3031 0.8481 3633812 CBKinase1_023995 CCN(CC(=O)O)S(=O)(=O)c1ccc(Br)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D14 compound treatment 3837037.0 94900.0 0.08 3798984.0 124000.0 0.1 0.1263 0.9947 3633813 CBKinase1_023996 COC(=O)c1ccccc1NC(=O)Cn2ccc(n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D15 mock treatment 4296437.0 554000.0 0.47 3978318.0 303000.0 0.24 0.5013 0.9527 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D16 mock treatment 4175985.0 434000.0 0.37 3837042.0 162000.0 0.13 0.3499 0.9018 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D17 compound treatment 3968067.0 226000.0 0.19 3892337.0 217000.0 0.17 0.257 0.9988 3633814 CBKinase1_023997 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D18 compound treatment 4354237.0 612000.0 0.52 4232647.0 557000.0 0.44 0.6791 0.9972 3633815 CBKinase1_023998 COC(=O)CC1(CC(=O)OC)C(=O)N(C)C(=O)N(C)C1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D19 compound treatment 4517200.0 775000.0 0.65 4013086.0 338000.0 0.27 0.6526 0.9231 3633816 CBKinase1_023999 Cc1cc(nc(SCC(=O)Nc2cccc(Cl)c2Cl)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D20 compound treatment 4723435.0 981000.0 0.83 4489064.0 814000.0 0.65 1.0439 0.9927 3633817 CBKinase1_024000 COc1cccc(c1)c2cc(n3nc(cc3n2)C(=O)Nc4cc(C)nn4c5ccccc5)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D21 compound treatment 4429065.0 687000.0 0.58 3992332.0 317000.0 0.25 0.5883 0.9308 3633818 CBKinase1_024001 CCn1c(SCC(=O)Nc2cc(C)ccc2OC)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D22 compound treatment 3985122.0 243000.0 0.2 4102815.0 427000.0 0.34 0.3858 0.9704 3633819 CBKinase1_024002 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3cc(ccc3Cl)C(F)(F)F)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D23 compound treatment 3867198.0 125000.0 0.11 3639979.0 -35400.0 -0.03 0.0546 0.5004 3633820 CBKinase1_024003 Cc1ccc(cc1)c2nc(c(SCC(=O)N)o2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 D24 compound treatment 3157249.0 -585000.0 -0.49 3074176.0 -601000.0 -0.48 -0.6877 -0.9999 3633821 CBKinase1_024004 CN(CC(=O)Nc1ccccc1C#N)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E01 mock treatment 1217484.0 -2520000.0 -2.13 1054664.0 -2620000.0 -2.09 -2.9828 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E02 mock treatment 1335904.0 -2410000.0 -2.03 1181225.0 -2490000.0 -1.99 -2.8409 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E03 compound treatment 1186549.0 -2560000.0 -2.16 1289018.0 -2390000.0 -1.9 -2.8692 -0.9981 3633822 CBKinase1_024005 [O-][N+](=O)c1ccccc1NC(=O)CCc2nc(no2)c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E04 compound treatment 1622128.0 -2120000.0 -1.79 1598439.0 -2080000.0 -1.66 -2.435 -0.9993 3633823 CBKinase1_024006 Cc1ccccc1OCC(=O)Nc2cc3nn(nc3cc2Cl)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E05 compound treatment 1865691.0 -1880000.0 -1.58 1640135.0 -2040000.0 -1.62 -2.2663 -0.9999 3633824 CBKinase1_024007 CC(=O)c1cccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E06 compound treatment 1957335.0 -1780000.0 -1.51 1790086.0 -1890000.0 -1.5 -2.1271 -1.0 3633825 CBKinase1_024008 COc1ccc(cc1)N2C(=O)CC(C2=O)n3c(CCCCO)nc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E07 compound treatment 1838677.0 -1900000.0 -1.61 1823960.0 -1850000.0 -1.48 -2.1788 -0.9991 3633826 CBKinase1_024009 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5cccs5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E08 compound treatment 2084978.0 -1660000.0 -1.4 2047674.0 -1630000.0 -1.3 -1.9058 -0.9993 3633827 CBKinase1_024010 FC(F)(F)c1cccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E09 mock treatment 2492458.0 -1250000.0 -1.05 2385191.0 -1290000.0 -1.03 -1.4725 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E10 mock treatment 2540330.0 -1200000.0 -1.01 2376990.0 -1300000.0 -1.03 -1.4486 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E11 compound treatment 2618408.0 -1120000.0 -0.95 2449796.0 -1230000.0 -0.98 -1.361 -0.9999 3633828 CBKinase1_024011 Cc1cc(OCC(=O)Nc2ccc(O)cc2C(=O)O)cc(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E12 compound treatment 2675430.0 -1070000.0 -0.9 2546842.0 -1130000.0 -0.9 -1.2723 -1.0 3633829 CBKinase1_024012 Cc1nn(C(=O)Cn2cc(cn2)[N+](=O)[O-])c(C)c1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E13 compound treatment 2705154.0 -1040000.0 -0.87 2441896.0 -1230000.0 -0.98 -1.3137 -0.9983 3633830 CBKinase1_024013 COc1ccccc1CNc2cc(ccc2C)c3nn4c(C)nnc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E14 compound treatment 2703056.0 -1040000.0 -0.88 2658537.0 -1020000.0 -0.81 -1.1929 -0.9992 3633831 CBKinase1_024014 CCN(CC(=O)Nc1ccccc1)S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E15 compound treatment 2605086.0 -1140000.0 -0.96 2853374.0 -822000.0 -0.66 -1.1415 -0.9827 3633832 CBKinase1_024015 CC1(C)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E16 compound treatment 2838898.0 -903000.0 -0.76 2887331.0 -788000.0 -0.63 -0.9829 -0.9954 3633833 CBKinase1_024016 Cn1c(NCc2ccco2)nc3n(C)c(=O)n(Cc4cccc(Br)c4)c(=O)c13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E17 mock treatment 3234748.0 -507000.0 -0.43 3007967.0 -667000.0 -0.53 -0.6788 -0.9942 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E18 mock treatment 3015135.0 -727000.0 -0.61 2865187.0 -810000.0 -0.65 -0.8902 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E19 compound treatment 3090108.0 -652000.0 -0.55 3556923.0 -118000.0 -0.09 -0.4557 -0.8165 3633834 CBKinase1_024017 CCC(N1C(=O)c2ccccc2C1=O)c3nc4ccccc4c(=O)n3c5ccccc5OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E20 compound treatment 2974157.0 -768000.0 -0.65 3287895.0 -387000.0 -0.31 -0.6765 -0.9426 3633835 CBKinase1_024018 Cc1coc(C)c1C(=O)CC2(O)C(=O)N(CCc3ccccc3)c4ccc(Cl)cc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E21 compound treatment 2789528.0 -953000.0 -0.8 2821756.0 -854000.0 -0.68 -1.0493 -0.9966 3633836 CBKinase1_024019 CCc1c(C)nc(SCC(=O)Nc2cccc(Br)c2)[nH]c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E22 compound treatment 3135700.0 -606000.0 -0.51 2762089.0 -913000.0 -0.73 -0.8764 -0.9851 3633837 CBKinase1_024020 Cc1ccc(c(Br)c1)n2c(S)nnc2Cn3c(nc4ccccc34)c5ccccn5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E23 compound treatment 3281671.0 -460000.0 -0.39 2803699.0 -872000.0 -0.69 -0.7659 -0.9623 3633838 CBKinase1_024021 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3cc(Cl)c(OC)cc3OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 E24 compound treatment 2141942.0 -1600000.0 -1.35 2285776.0 -1390000.0 -1.11 -1.7376 -0.9952 3633839 CBKinase1_024022 Cn1c(=O)n(C)c2ncn(Cc3cc(no3)c4ccccc4)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F01 mock treatment 1048344.0 -2690000.0 -2.27 970291.0 -2710000.0 -2.16 -3.1313 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F02 mock treatment 1330451.0 -2410000.0 -2.03 1295906.0 -2380000.0 -1.9 -2.7795 -0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F03 compound treatment 1403494.0 -2340000.0 -1.97 1324450.0 -2350000.0 -1.87 -2.7199 -0.9997 3633840 CBKinase1_024023 Cc1c(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F04 compound treatment 1638348.0 -2100000.0 -1.77 1530116.0 -2150000.0 -1.71 -2.4639 -0.9998 3633841 CBKinase1_024024 COC(=O)CN(c1cccc(c1)C(=O)C)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F05 compound treatment 2103017.0 -1640000.0 -1.38 1804875.0 -1870000.0 -1.49 -2.0319 -0.9993 3633842 CBKinase1_024025 COc1cc2c(cc1NC(=O)CN(C)S(=O)(=O)c3ccc(Br)cc3)oc4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F06 compound treatment 1834292.0 -1910000.0 -1.61 2184659.0 -1490000.0 -1.19 -1.9781 -0.9889 3633843 CBKinase1_024026 CCn1c(SCC(=O)Nc2sc3CCCCc3c2C#N)nnc1c4ccccc4O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F07 compound treatment 2019121.0 -1720000.0 -1.45 1780948.0 -1890000.0 -1.51 -2.0954 -0.9998 3633844 CBKinase1_024027 OC(=O)COc1ccc(NC(=O)c2cccc(I)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F08 compound treatment 2902760.0 -839000.0 -0.71 2449160.0 -1230000.0 -0.98 -1.1917 -0.9875 3633845 CBKinase1_024028 Cc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)Cc4coc5ccc(C)cc45)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F09 mock treatment 2039219.0 -1700000.0 -1.44 2572825.0 -1100000.0 -0.88 -1.6371 -0.9722 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F10 mock treatment 2363404.0 -1380000.0 -1.16 2410468.0 -1260000.0 -1.01 -1.5352 -0.9975 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F11 compound treatment 5130743.0 1390000.0 1.17 4932642.0 1260000.0 1.0 1.5368 0.997 3633846 CBKinase1_024029 COc1cc(NC(=O)COc2ccccc2Cl)ccc1NC(=O)c3cc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F12 compound treatment 2747688.0 -994000.0 -0.84 2172691.0 -1500000.0 -1.2 -1.4401 -0.9848 3633847 CBKinase1_024030 CCn1c(SCC(=O)N2CCN(CC2)c3ccccc3)nnc1c4ccccc4O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F13 compound treatment 2298834.0 -1440000.0 -1.22 2192456.0 -1480000.0 -1.18 -1.6966 -0.9999 3633848 CBKinase1_024031 COc1ccc(C2C(=C(C)Nc3ncnn23)C(=O)Nc4cc(OC)c(Cl)cc4OC)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F14 compound treatment 2510415.0 -1230000.0 -1.04 2302880.0 -1370000.0 -1.09 -1.5082 -0.9997 3633849 CBKinase1_024032 CC(C)NC(=O)Cn1nc(cc1C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F15 compound treatment 2779811.0 -962000.0 -0.81 2611637.0 -1060000.0 -0.85 -1.1735 -0.9998 3633850 CBKinase1_024033 COC(=O)c1cc(OC)c(OC)cc1NC(=S)N2CCC(CC2)(N3CCCCC3)C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F16 compound treatment 2645214.0 -1100000.0 -0.93 2714419.0 -961000.0 -0.77 -1.1959 -0.9956 3633851 CBKinase1_024034 COc1ccc(Cc2nnc(SCc3nc4ccccc4c(=O)[nH]3)o2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F17 mock treatment 2681483.0 -1060000.0 -0.89 2707117.0 -968000.0 -0.77 -1.1783 -0.9973 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F18 mock treatment 2624448.0 -1120000.0 -0.94 2798467.0 -877000.0 -0.7 -1.1609 -0.9891 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F19 compound treatment 2948791.0 -793000.0 -0.67 2750553.0 -925000.0 -0.74 -0.9944 -0.9988 3633852 CBKinase1_024035 CN(C)c1nc(N)nc(CSc2ccccn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F20 compound treatment 2653447.0 -1090000.0 -0.92 2608947.0 -1070000.0 -0.85 -1.2504 -0.9993 3633853 CBKinase1_024036 Cc1nc2ncnn2c(O)c1NS(=O)(=O)c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F21 compound treatment 2664593.0 -1080000.0 -0.91 2235677.0 -1440000.0 -1.15 -1.4541 -0.9933 3633854 CBKinase1_024037 [O-][N+](=O)c1nc(Oc2ccccc2C(=O)N3CCCC3)n(Cc4ccccc4F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F22 compound treatment 2971728.0 -770000.0 -0.65 2911911.0 -763000.0 -0.61 -0.8898 -0.9995 3633855 CBKinase1_024038 CN(Cc1nc(no1)c2cccnc2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F23 compound treatment 3112876.0 -629000.0 -0.53 2679746.0 -996000.0 -0.79 -0.9365 -0.9809 3633856 CBKinase1_024039 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)C)nnc1c3cc(Br)ccc3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 F24 compound treatment 2493787.0 -1250000.0 -1.05 2147125.0 -1530000.0 -1.22 -1.6059 -0.9974 3633857 CBKinase1_024040 COc1ccccc1NC(=O)Cn2cc(C(=O)C3CCCCC3)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G01 compound treatment 3224869.0 -517000.0 -0.44 2158964.0 -1520000.0 -1.21 -1.1632 -0.9052 3633858 CBKinase1_024041 Cc1cc(nn1CC(=O)Nc2ccc(F)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G02 compound treatment 3570696.0 -171000.0 -0.14 2848662.0 -827000.0 -0.66 -0.5682 -0.8423 3633859 CBKinase1_024042 Cc1cc(nn1CC(=O)n2nc(C)c(Cl)c2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G03 mock treatment 3055978.0 -686000.0 -0.58 3563130.0 -112000.0 -0.09 -0.4725 -0.8068 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G04 mock treatment 3282306.0 -460000.0 -0.39 3145024.0 -530000.0 -0.42 -0.5732 -0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G05 compound treatment 3517994.0 -224000.0 -0.19 3202657.0 -473000.0 -0.38 -0.4001 -0.9492 3633860 CBKinase1_024043 COc1ccc(cc1OC)c2nnc(SCC(=O)O)n2c3cccc(c3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G06 compound treatment 3401805.0 -340000.0 -0.29 3450030.0 -225000.0 -0.18 -0.33 -0.9745 3633861 CBKinase1_024044 CCOc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G07 compound treatment 3324033.0 -418000.0 -0.35 3609079.0 -66300.0 -0.05 -0.2868 -0.8041 3633862 CBKinase1_024045 COC(=O)c1ccccc1NC(=O)CSc2nc3cc4ccccc4cc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G08 compound treatment 3850321.0 108000.0 0.09 3478484.0 -197000.0 -0.16 -0.0465 -0.2559 3633863 CBKinase1_024046 CCCN1C(=C(C(=O)OC)C(NS(=O)(=O)c2ccc(N)cc2)(C1=O)C(F)(F)F)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G09 compound treatment 3449377.0 -293000.0 -0.25 3454381.0 -221000.0 -0.18 -0.2992 -0.9863 3633864 CBKinase1_024047 Cn1c(Cc2ccccc2)nnc1Sc3ccc(cc3C(=O)N4CCOCC4)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G10 compound treatment 3386880.0 -355000.0 -0.3 3717955.0 42600.0 0.03 -0.1879 -0.623 3633865 CBKinase1_024048 [O-][N+](=O)c1cnn(CCCC(=O)Nc2cccc(c2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G11 compound treatment 3456892.0 -285000.0 -0.24 3727319.0 52000.0 0.04 -0.1409 -0.5769 3633866 CBKinase1_024049 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(F)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G12 compound treatment 3619556.0 -123000.0 -0.1 3582525.0 -92800.0 -0.07 -0.1255 -0.9865 3633867 CBKinase1_024050 Cc1cc(C)c(NC(=O)CSc2nnc(s2)c3cccnc3)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G13 compound treatment 3333319.0 -409000.0 -0.34 3412929.0 -262000.0 -0.21 -0.3918 -0.9713 3633868 CBKinase1_024051 CC(C)N(Cc1nc(no1)c2ccccc2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G14 compound treatment 3620979.0 -121000.0 -0.1 3271557.0 -404000.0 -0.32 -0.2999 -0.888 3633869 CBKinase1_024052 CC(C(=O)N1CCOCC1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G15 compound treatment 3305733.0 -436000.0 -0.37 3767545.0 92200.0 0.07 -0.2084 -0.555 3633870 CBKinase1_024053 Cc1nn(CC(=O)NCc2ccccc2Cl)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G16 compound treatment 3513426.0 -229000.0 -0.19 3295833.0 -380000.0 -0.3 -0.3503 -0.9764 3633871 CBKinase1_024054 COC(=O)c1ccc(NC(=O)CSc2nc(O)cc(n2)c3cccs3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G17 compound treatment 3651597.0 -90600.0 -0.08 3559364.0 -116000.0 -0.09 -0.1194 -0.9955 3633872 CBKinase1_024055 Fc1cc(F)c(NC(=O)CSc2nc(c3CCc4ccccc4-c3n2)C(F)(F)F)c(Br)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G18 compound treatment 3853577.0 111000.0 0.09 3377541.0 -298000.0 -0.24 -0.1014 -0.3972 3633873 CBKinase1_024056 Cc1ccc(cc1)c2cn(nc2N)S(=O)(=O)c3cccc4nsnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G19 mock treatment 4336571.0 594000.0 0.5 3853286.0 178000.0 0.14 0.4548 0.8729 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G20 mock treatment 3967683.0 226000.0 0.19 4215912.0 541000.0 0.43 0.4392 0.9325 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G21 compound treatment 3592399.0 -150000.0 -0.13 4041685.0 366000.0 0.29 0.1171 0.3682 3633874 CBKinase1_024057 Fc1ccccc1NC(=O)COc2ccc(cc2Cl)S(=O)(=O)N3CCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G22 compound treatment 4047830.0 306000.0 0.26 4043120.0 368000.0 0.29 0.3896 0.998 3633875 CBKinase1_024058 CN(Cc1cn(C)nc1C)C(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G23 compound treatment 2926876.0 -815000.0 -0.69 3263891.0 -411000.0 -0.33 -0.7182 -0.9426 3633876 CBKinase1_024059 COc1ccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 G24 compound treatment 3114723.0 -627000.0 -0.53 2407769.0 -1270000.0 -1.01 -1.0886 -0.9545 3633877 CBKinase1_024060 [O-][N+](=O)c1cnn(CCCC(=O)Nc2ccc(C#N)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H01 compound treatment 2951141.0 -791000.0 -0.67 2587373.0 -1090000.0 -0.87 -1.085 -0.9916 3633878 CBKinase1_024061 Cc1cc(I)ccc1NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H02 compound treatment 3729736.0 -12400.0 -0.01 2911283.0 -764000.0 -0.61 -0.438 -0.7192 3633879 CBKinase1_024062 FC(F)(F)c1cccc(NC(=O)CSCc2nc3ccccc3[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H03 mock treatment 3316445.0 -426000.0 -0.36 3536166.0 -139000.0 -0.11 -0.3324 -0.8843 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H04 mock treatment 3648669.0 -93500.0 -0.08 3340256.0 -335000.0 -0.27 -0.2446 -0.8784 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H05 compound treatment 3381977.0 -360000.0 -0.3 3558194.0 -117000.0 -0.09 -0.2809 -0.8837 3633880 CBKinase1_024063 COc1ccccc1NC(=O)Cn2cc(C(=O)c3ccccc3F)c4ccccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H06 compound treatment 3203626.0 -539000.0 -0.45 3513268.0 -162000.0 -0.13 -0.4126 -0.8736 3633881 CBKinase1_024064 COc1ccccc1NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H07 compound treatment 3363401.0 -379000.0 -0.32 3563252.0 -112000.0 -0.09 -0.2891 -0.8714 3633882 CBKinase1_024065 COc1ccc(cc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H08 compound treatment 3971422.0 229000.0 0.19 3583625.0 -91700.0 -0.07 0.085 0.4113 3633883 CBKinase1_024066 COc1ccc(OC)c(c1)c2nc(C)sc2CC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H09 compound treatment 3759311.0 17100.0 0.01 3557880.0 -117000.0 -0.09 -0.056 -0.5909 3633884 CBKinase1_024067 COc1ccc(cc1OC)c2noc(CSc3nc(cc(=O)[nH]3)c4ccccc4)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H10 compound treatment 3564016.0 -178000.0 -0.15 3883672.0 208000.0 0.17 0.0111 0.0498 3633885 CBKinase1_024068 Cc1ccc(NC(=O)CCCn2cc(cn2)[N+](=O)[O-])cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H11 compound treatment 3664711.0 -77500.0 -0.07 4039361.0 364000.0 0.29 0.1589 0.5345 3633886 CBKinase1_024069 COc1cccc(NC(=O)CNC(=O)c2cccs2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H12 compound treatment 3327123.0 -415000.0 -0.35 3748679.0 73300.0 0.06 -0.2062 -0.581 3633887 CBKinase1_024070 CCc1ccccc1NC(=O)COc2cc(O)c3c(=O)cc(oc3c2)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H13 compound treatment 3348932.0 -393000.0 -0.33 3519597.0 -156000.0 -0.12 -0.3223 -0.9101 3633888 CBKinase1_024071 Cc1c(Br)c(nn1CC(=O)Nc2ccc(F)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H14 compound treatment 3833975.0 91800.0 0.08 3549518.0 -126000.0 -0.1 -0.0162 -0.1276 3633889 CBKinase1_024072 Clc1ccc(cc1)C(=O)CSc2nnc3c4ccccc4n(CC=C)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H15 compound treatment 3202563.0 -540000.0 -0.46 2961454.0 -714000.0 -0.57 -0.7242 -0.9939 3633890 CBKinase1_024073 COCCNc1c(nn(c2ccccc2)[n+]1[O-])[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H16 compound treatment 3965283.0 223000.0 0.19 3778460.0 103000.0 0.08 0.1912 0.931 3633891 CBKinase1_024074 Cc1ccc(cc1)c2cc(no2)C(=O)NCc3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H17 compound treatment 3954267.0 212000.0 0.18 3754045.0 78700.0 0.06 0.1708 0.9012 3633892 CBKinase1_024075 O=C(CSc1nc2ccccc2c(=O)n1Cc3ccccc3)c4cc5ccccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H18 compound treatment 3946138.0 204000.0 0.17 3726450.0 51100.0 0.04 0.1504 0.8509 3633893 CBKinase1_024076 NC(=O)CSc1nnc(Cc2ccccc2)n1c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H19 mock treatment 4266703.0 525000.0 0.44 4148646.0 473000.0 0.38 0.5796 0.9968 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H20 mock treatment 4558284.0 816000.0 0.69 4424099.0 749000.0 0.6 0.9087 0.9975 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H21 compound treatment 4312987.0 571000.0 0.48 3044024.0 -631000.0 -0.5 -0.0154 -0.0221 3028941 CBKinase1_024077 Cc1cc(C)n(n1)c2nc3ccccc3nc2N4CCN(CC4)S(=O)(=O)c5ccc(F)c(C)c5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H22 compound treatment 4360784.0 619000.0 0.52 4435227.0 760000.0 0.61 0.7972 0.9972 3633894 CBKinase1_024078 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H23 compound treatment 4204864.0 463000.0 0.39 4141462.0 466000.0 0.37 0.5387 0.9997 3633895 CBKinase1_024079 CN(Cc1nnc(S)n1C)S(=O)(=O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 H24 compound treatment 3135091.0 -607000.0 -0.51 3610210.0 -65200.0 -0.05 -0.3988 -0.7748 3633896 CBKinase1_024080 COc1ccc(OC)c(NC(=O)CNC(=O)c2ccc(Cl)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I01 compound treatment 3393157.0 -349000.0 -0.29 2626161.0 -1050000.0 -0.84 -0.7995 -0.9018 3633897 CBKinase1_024081 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)CN3CCOCC3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I02 compound treatment 3412772.0 -329000.0 -0.28 2878321.0 -797000.0 -0.64 -0.6457 -0.9312 3633898 CBKinase1_024082 COc1ccc(cc1OC)C(=O)CSc2nc(SC)ns2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I03 compound treatment 3591473.0 -151000.0 -0.13 2970957.0 -704000.0 -0.56 -0.4869 -0.8458 3633899 CBKinase1_024083 Cc1ccc(cc1NC(=O)CCN2C(=O)c3ccccc3C2=O)C(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I04 compound treatment 3799744.0 57600.0 0.05 2890476.0 -785000.0 -0.63 -0.408 -0.6503 3633900 CBKinase1_024084 Cc1nn(CC(=O)Nc2cccnc2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I05 mock treatment 3655336.0 -86800.0 -0.07 3647736.0 -27600.0 -0.02 -0.0674 -0.8808 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I06 mock treatment 3978408.0 236000.0 0.2 3807077.0 132000.0 0.1 0.2151 0.9552 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I07 compound treatment 3417788.0 -324000.0 -0.27 3284819.0 -391000.0 -0.31 -0.4136 -0.9979 3633901 CBKinase1_024085 CCOc1ccc(cc1)n2c(SCc3nc(no3)c4cccs4)nnc2c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I08 compound treatment 4058407.0 316000.0 0.27 3921261.0 246000.0 0.2 0.3272 0.9885 3633902 CBKinase1_024086 CC(=O)c1cccc(NC(=O)CCCn2cc(cn2)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I09 compound treatment 3484538.0 -258000.0 -0.22 3480441.0 -195000.0 -0.16 -0.2635 -0.9865 3633903 CBKinase1_024087 CCNS(=O)(=O)c1cc(C)ccc1n2cnnn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I10 compound treatment 3786838.0 44700.0 0.04 3861805.0 186000.0 0.15 0.1317 0.8592 3633904 CBKinase1_024088 COc1ccc(OC)c(NC(=O)Cn2nc(cc2C)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I11 compound treatment 3892998.0 151000.0 0.13 3991809.0 316000.0 0.25 0.2683 0.9498 3633905 CBKinase1_024089 Clc1ccc(CS(=O)(=O)NCc2ccccn2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I12 compound treatment 3939215.0 197000.0 0.17 3979779.0 304000.0 0.24 0.2891 0.983 3633906 CBKinase1_024090 Cc1c(Br)c(nn1CC(=O)NCc2ccccn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I13 compound treatment 4228256.0 486000.0 0.41 4232860.0 557000.0 0.44 0.6041 0.9992 3633907 CBKinase1_024091 CC(=O)NCCOc1nc(nc(n1)N2CCOCC2)N3CCCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I14 compound treatment 4132980.0 391000.0 0.33 4224059.0 549000.0 0.44 0.5423 0.9903 3633908 CBKinase1_024092 CC(C)N(Cc1nc(no1)c2ccccc2)S(=O)(=O)c3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I15 compound treatment 3492191.0 -250000.0 -0.21 4094897.0 420000.0 0.33 0.0873 0.221 3633909 CBKinase1_024093 Cc1nn(CC(=O)Nc2cc(F)ccc2F)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I16 compound treatment 4077188.0 335000.0 0.28 4490746.0 815000.0 0.65 0.6594 0.9304 3633910 CBKinase1_024094 CC1CCc2c(C#N)c(NC(=O)Cn3nc(c4CCCCCc43)C(F)(F)F)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I17 compound treatment 3560473.0 -182000.0 -0.15 4140278.0 465000.0 0.37 0.1537 0.3832 3633911 CBKinase1_024095 Cc1cc(ccc1NC(=O)COc2ccccc2[N+](=O)[O-])c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I18 compound treatment 4013904.0 272000.0 0.23 3658848.0 -16500.0 -0.01 0.1528 0.6654 3633912 CBKinase1_024096 COc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)N(C)Cc4cnn(C)c4C)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I19 compound treatment 4723025.0 981000.0 0.83 4739918.0 1060000.0 0.85 1.185 0.9999 1241281 CBKinase1_024097 COc1cc(NC(=O)c2cc3ccccc3cc2OCC(=O)NC(C)(C)C)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I20 compound treatment 4682875.0 941000.0 0.79 4074638.0 399000.0 0.32 0.7861 0.9195 3633913 CBKinase1_024098 CC(=O)Nc1ccc(NC(=O)Cn2ccc(n2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I21 mock treatment 4740266.0 998000.0 0.84 3630883.0 -44500.0 -0.04 0.5702 0.6767 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I22 mock treatment 4500889.0 759000.0 0.64 3245285.0 -430000.0 -0.34 0.2101 0.2895 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I23 compound treatment 4194766.0 453000.0 0.38 3922907.0 248000.0 0.2 0.4095 0.9528 3633914 CBKinase1_024099 COc1ccccc1CNC(=O)c2ccc(NS(=O)(=O)C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 I24 compound treatment 3529036.0 -213000.0 -0.18 3467745.0 -208000.0 -0.17 -0.2441 -0.9991 3633915 CBKinase1_024100 COc1ccc(cc1)N2C(CC(=O)Nc3ccc(F)cc3)C(=O)N(C2=O)c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J01 compound treatment 2999151.0 -743000.0 -0.63 2631000.0 -1040000.0 -0.83 -1.0318 -0.9902 3633916 CBKinase1_024101 CN(CC(=O)Nc1ccccc1c2ccccc2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J02 compound treatment 3616416.0 -126000.0 -0.11 3300920.0 -374000.0 -0.3 -0.286 -0.9031 3633917 CBKinase1_024102 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc3OCCOc3c2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J03 compound treatment 3264938.0 -477000.0 -0.4 3319415.0 -356000.0 -0.28 -0.4853 -0.9853 3633918 CBKinase1_024103 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J04 compound treatment 3288193.0 -454000.0 -0.38 3268508.0 -407000.0 -0.32 -0.5001 -0.9966 3633919 CBKinase1_024104 COc1cc(Cc2nccc3cc(OC)c(OC)cc23)c(NC(=O)c4cccc(Br)c4)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J05 mock treatment 3564088.0 -178000.0 -0.15 3464798.0 -211000.0 -0.17 -0.2249 -0.9985 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J06 mock treatment 3797236.0 55100.0 0.05 3950286.0 275000.0 0.22 0.1878 0.8384 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J07 compound treatment 3407519.0 -335000.0 -0.28 3717835.0 42500.0 0.03 -0.1757 -0.6179 3633920 CBKinase1_024105 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccc(Cl)c(Cl)c4)c5ccccc51 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J08 compound treatment 3603731.0 -138000.0 -0.12 3687619.0 12300.0 0.01 -0.0757 -0.6457 3633921 CBKinase1_024106 Cc1cc(C)c(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J09 compound treatment 4130456.0 388000.0 0.33 4202548.0 527000.0 0.42 0.5287 0.9924 3633922 CBKinase1_024107 CCn1c(SCC(=O)Nc2cc(C)c(C)cc2Br)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J10 compound treatment 3971310.0 229000.0 0.19 4082884.0 408000.0 0.32 0.3663 0.9693 3633923 CBKinase1_024108 NC(=O)C1(CCN(CC(=O)Nc2ccccc2Sc3ccccc3)CC1)N4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J11 compound treatment 4270508.0 528000.0 0.45 4406617.0 731000.0 0.58 0.7273 0.9912 3633924 CBKinase1_024109 CCn1c(SCC(=O)Nc2cccc(c2)C(F)(F)F)nnc1c3c[nH]c4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J12 compound treatment 4154630.0 412000.0 0.35 3898425.0 223000.0 0.18 0.3717 0.9514 3633925 CBKinase1_024110 COc1ccc(cc1)c2nnc(SCC(=O)c3cccc(c3)[N+](=O)[O-])n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J13 compound treatment 4610025.0 868000.0 0.73 4403012.0 728000.0 0.58 0.9277 0.9933 3633926 CBKinase1_024111 CCn1c(SCC(=O)Nc2ccc(Br)cc2C)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J14 compound treatment 4495298.0 753000.0 0.64 4292855.0 617000.0 0.49 0.7972 0.992 3633927 CBKinase1_024112 OC(=O)CCCNS(=O)(=O)c1ccc(Br)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J15 compound treatment 3680500.0 -61700.0 -0.05 4235195.0 560000.0 0.45 0.2787 0.6205 3633928 CBKinase1_024113 COC(=O)COc1ccc(NC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J16 compound treatment 4377356.0 635000.0 0.54 4223210.0 548000.0 0.44 0.6876 0.9948 3633929 CBKinase1_024114 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2c(C)nc(O)nc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J17 compound treatment 4606038.0 864000.0 0.73 4641508.0 966000.0 0.77 1.0598 0.9996 3633930 CBKinase1_024115 COc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c2cc(C)ccc2OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J18 compound treatment 4181815.0 440000.0 0.37 3974137.0 299000.0 0.24 0.4306 0.9771 3633931 CBKinase1_024116 C(Oc1cccc2cccnc12)c3nc4ccccc4[nH]3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J19 compound treatment 4550454.0 808000.0 0.68 4620710.0 945000.0 0.75 1.0149 0.9988 3633932 CBKinase1_024117 COc1ccc(OC)c(NC(=O)COc2ccc3c4CCCCc4c(=O)oc3c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J20 compound treatment 4678661.0 936000.0 0.79 4309702.0 634000.0 0.51 0.9161 0.9768 3633933 CBKinase1_024118 Clc1cc(ccc1OCC(=O)Nc2ccc3OCCOc3c2)S(=O)(=O)N4CCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J21 mock treatment 4482840.0 741000.0 0.62 4452126.0 777000.0 0.62 0.8795 1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J22 mock treatment 4479265.0 737000.0 0.62 4149997.0 475000.0 0.38 0.7071 0.9716 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J23 compound treatment 4101191.0 359000.0 0.3 4121167.0 446000.0 0.36 0.4654 0.9968 3633934 CBKinase1_024119 CC(=O)c1cccc(NC(=O)CCN2C(=O)C3C4CCC(C4)C3C2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 J24 compound treatment 3825950.0 83800.0 0.07 3648020.0 -27300.0 -0.02 0.0346 0.4673 3633935 CBKinase1_024120 Cc1ccc(NS(=O)(=O)c2cc(ccc2Cl)C(=O)Nc3ccccc3C(=O)N4CCCC4)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K01 compound treatment 1382212.0 -2360000.0 -1.99 1475010.0 -2200000.0 -1.75 -2.6477 -0.998 3633936 CBKinase1_024121 Clc1ccc(cc1)c2noc(CCC(=O)NC3CCCCC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K02 compound treatment 3116640.0 -626000.0 -0.53 1818706.0 -1860000.0 -1.48 -1.4195 -0.9035 3633937 CBKinase1_024122 Cc1nn(C(=O)Cn2ccc(n2)[N+](=O)[O-])c(C)c1I 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K03 compound treatment 3268242.0 -474000.0 -0.4 2416433.0 -1260000.0 -1.0 -0.9922 -0.9186 3633938 CBKinase1_024123 Cc1cccc(c1)c2nnc(SCc3nc4ccccc4c(=O)[nH]3)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K04 compound treatment 3766121.0 24000.0 0.02 3911932.0 237000.0 0.19 0.1476 0.7784 3633939 CBKinase1_024124 Cc1nn(CC(O)COc2ccc3CCCc3c2)c(C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K05 compound treatment 3611353.0 -131000.0 -0.11 3517213.0 -158000.0 -0.13 -0.1672 -0.9978 3633940 CBKinase1_024125 OC(=O)c1cc(O)ccc1NC(=O)Cc2cccc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K06 compound treatment 3386411.0 -356000.0 -0.3 3363285.0 -312000.0 -0.25 -0.3881 -0.9957 3633941 CBKinase1_024126 FC(F)c1cc(nc2c(cnn12)C(=O)NCCCN3CCOCC3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K07 mock treatment 3493101.0 -249000.0 -0.21 3201188.0 -474000.0 -0.38 -0.4158 -0.9616 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K08 mock treatment 3175687.0 -566000.0 -0.48 3531279.0 -144000.0 -0.11 -0.4191 -0.8528 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K09 compound treatment 3419951.0 -322000.0 -0.27 3534903.0 -140000.0 -0.11 -0.2713 -0.9231 3633942 CBKinase1_024127 CN(C)C(=O)CSc1nnc(c2cccnc2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K10 compound treatment 3297184.0 -445000.0 -0.38 3606590.0 -68800.0 -0.05 -0.3042 -0.8019 3633943 CBKinase1_024128 CCOc1cc(ccc1Cl)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K11 compound treatment 3392212.0 -350000.0 -0.3 3790440.0 115000.0 0.09 -0.1439 -0.4654 3633944 CBKinase1_024129 COc1ccccc1NC(=O)C2CCCN(C2)S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K12 compound treatment 3155842.0 -586000.0 -0.49 3242913.0 -432000.0 -0.34 -0.5934 -0.9844 3633945 CBKinase1_024130 COc1ccc(cc1)c2noc(CN(C(C)C)S(=O)(=O)c3ccccc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K13 compound treatment 3282670.0 -459000.0 -0.39 3257701.0 -418000.0 -0.33 -0.5095 -0.9971 3633946 CBKinase1_024131 Cc1nc(SCCC(=O)Nc2ccccc2C#N)nc3cc4CCCc4cc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K14 compound treatment 3285452.0 -457000.0 -0.39 3242912.0 -432000.0 -0.34 -0.5161 -0.9985 3633947 CBKinase1_024132 Cc1nn(CC(=O)Nc2ccc(Br)cc2C)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K15 mock treatment 3458251.0 -284000.0 -0.24 3186814.0 -489000.0 -0.39 -0.4447 -0.9727 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K16 mock treatment 3499384.0 -243000.0 -0.2 3827488.0 152000.0 0.12 -0.0591 -0.2482 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K17 compound treatment 3425047.0 -317000.0 -0.27 3638943.0 -36400.0 -0.03 -0.2097 -0.7793 3633948 CBKinase1_024133 COc1cc(C)c(Br)cc1S(=O)(=O)NCC2CCCO2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K18 compound treatment 3011197.0 -731000.0 -0.62 3246555.0 -429000.0 -0.34 -0.6777 -0.9613 3633949 CBKinase1_024134 CCOC(=O)c1c(NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K19 compound treatment 3336013.0 -406000.0 -0.34 4695876.0 1020000.0 0.81 0.3329 0.3772 3633950 CBKinase1_024135 Cc1nn(CC(=O)Nc2ccc3n(C)c(CN4CCCC4)nc3c2)c(=O)c5ccccc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K20 compound treatment 5119209.0 1380000.0 1.16 3179107.0 -496000.0 -0.4 0.5416 0.4414 3633951 CBKinase1_024136 Cc1ccc(cc1)c2noc(CSc3nnc(c4ccncc4)n3c5ccc(C)cc5)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K21 compound treatment 3759665.0 17500.0 0.01 3425275.0 -250000.0 -0.2 -0.1305 -0.653 3633952 CBKinase1_024137 Clc1ccc(cc1)c2noc(CCC(=O)N3CCOCC3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K22 compound treatment 3057624.0 -685000.0 -0.58 3122600.0 -553000.0 -0.44 -0.7198 -0.9911 3633953 CBKinase1_024138 CC(C(=O)Nc1cc(Cl)ccc1C)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K23 mock treatment 3087947.0 -654000.0 -0.55 3368356.0 -307000.0 -0.24 -0.5632 -0.933 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 K24 mock treatment 2911359.0 -831000.0 -0.7 2868201.0 -807000.0 -0.64 -0.9504 -0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L01 compound treatment 1880499.0 -1860000.0 -1.57 2370357.0 -1310000.0 -1.04 -1.8459 -0.98 3633954 CBKinase1_024139 Cc1cc(OCC(=O)NCc2ccccn2)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L02 compound treatment 2335763.0 -1410000.0 -1.19 2769557.0 -906000.0 -0.72 -1.3493 -0.9716 3633955 CBKinase1_024140 Cc1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L03 compound treatment 3463305.0 -279000.0 -0.24 3367750.0 -308000.0 -0.25 -0.3397 -0.9998 3633956 CBKinase1_024141 Cc1ccc(NS(=O)(=O)c2cc(ccc2Cl)C(=O)NCC3CCCO3)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L04 compound treatment 3923590.0 181000.0 0.15 3742845.0 67500.0 0.05 0.1462 0.9016 3633957 CBKinase1_024142 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)C3CCCCC3)c4ccccc24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L05 compound treatment 4136126.0 394000.0 0.33 3462234.0 -213000.0 -0.17 0.1149 0.3077 3633958 CBKinase1_024143 CCn1c(SCC(=O)N2CCc3ccccc23)nnc1c4c[nH]c5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L06 compound treatment 3726459.0 -15700.0 -0.01 3877848.0 202000.0 0.16 0.1047 0.6469 3633959 CBKinase1_024144 CS(=O)(=O)NC(C(=O)O)c1ccccc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L07 mock treatment 3881040.0 139000.0 0.12 3741049.0 65700.0 0.05 0.1198 0.9341 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L08 mock treatment 3820599.0 78400.0 0.07 4050905.0 376000.0 0.3 0.2584 0.843 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L09 compound treatment 3605982.0 -136000.0 -0.11 3445908.0 -229000.0 -0.18 -0.2105 -0.9749 3633960 CBKinase1_024145 Cn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4cc5cc(Br)ccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L10 compound treatment 3189677.0 -552000.0 -0.47 3637177.0 -38200.0 -0.03 -0.3511 -0.7517 3633961 CBKinase1_024146 [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCOc2cccc3cccnc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L11 compound treatment 3428604.0 -314000.0 -0.26 3382936.0 -292000.0 -0.23 -0.3518 -0.998 3633962 CBKinase1_024147 CCOc1ccccc1c2nnc(SCC(=O)Nc3ccc(I)cc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L12 compound treatment 3663854.0 -78300.0 -0.07 3394272.0 -281000.0 -0.22 -0.2051 -0.8782 3633963 CBKinase1_024148 CN1CCN(CC1)c2ccccc2NC(=O)COc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L13 compound treatment 3770838.0 28700.0 0.02 3444327.0 -231000.0 -0.18 -0.1131 -0.609 3633964 CBKinase1_024149 Fc1ccccc1c2noc(CCC(=O)Nc3cccnc3)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L14 compound treatment 3290407.0 -452000.0 -0.38 3379090.0 -296000.0 -0.24 -0.4364 -0.9735 3633965 CBKinase1_024150 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)NCc3ccccn3)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L15 mock treatment 3372055.0 -370000.0 -0.31 3499586.0 -176000.0 -0.14 -0.3198 -0.9346 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L16 mock treatment 3375864.0 -366000.0 -0.31 3549823.0 -126000.0 -0.1 -0.2892 -0.8906 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L17 compound treatment 3113390.0 -629000.0 -0.53 3402765.0 -273000.0 -0.22 -0.5287 -0.9224 3633966 CBKinase1_024151 O=C(CN1CCc2ccccc2C1)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L18 compound treatment 3199778.0 -542000.0 -0.46 3185739.0 -490000.0 -0.39 -0.5995 -0.9969 3633967 CBKinase1_024152 CCOc1ccc(NC(=O)C(C)Sc2ncnc3sc(cc23)c4ccccc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L19 compound treatment 3325590.0 -417000.0 -0.35 3562139.0 -113000.0 -0.09 -0.3123 -0.8608 3633968 CBKinase1_024153 FC(F)(Cl)c1cc(nc2cc(nn12)C(=O)NCc3ccco3)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L20 compound treatment 2964042.0 -778000.0 -0.66 3644004.0 -31400.0 -0.02 -0.4818 -0.7335 3633969 CBKinase1_024154 CN(CCCC(=O)O)c1nc(cs1)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L21 compound treatment 4867603.0 1130000.0 0.95 3131096.0 -544000.0 -0.43 0.3645 0.3492 1458541 CBKinase1_024155 O=C(COc1ccc(cc1)S(=O)(=O)N2CCOCC2)Nc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L22 compound treatment 3440040.0 -302000.0 -0.25 3451726.0 -224000.0 -0.18 -0.3062 -0.9847 3633970 CBKinase1_024156 Clc1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L23 mock treatment 3144769.0 -597000.0 -0.5 3706147.0 30800.0 0.02 -0.339 -0.6719 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 L24 mock treatment 2957680.0 -784000.0 -0.66 3015824.0 -660000.0 -0.53 -0.8396 -0.9935 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M01 compound treatment 2702972.0 -1040000.0 -0.88 2926161.0 -749000.0 -0.6 -1.0421 -0.9825 3633971 CBKinase1_024157 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)C(C)Oc3ccc(Cl)cc3C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M02 compound treatment 3421940.0 -320000.0 -0.27 3236100.0 -439000.0 -0.35 -0.4386 -0.9918 3633972 CBKinase1_024158 Clc1cc(Cl)cc(NC(=O)CSc2nnnn2c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M03 compound treatment 3248049.0 -494000.0 -0.42 3268346.0 -407000.0 -0.32 -0.5241 -0.9923 3633973 CBKinase1_024159 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCCCN3CCOCC3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M04 compound treatment 3834900.0 92700.0 0.08 4068624.0 393000.0 0.31 0.2769 0.8573 3633974 CBKinase1_024160 COc1ccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M05 compound treatment 4175350.0 433000.0 0.37 4310255.0 635000.0 0.51 0.6162 0.9872 3633975 CBKinase1_024161 CCn1c(SCC(=O)N2CCc3ccccc23)nnc1c4ccccc4O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M06 compound treatment 4452314.0 710000.0 0.6 4227360.0 552000.0 0.44 0.7347 0.9885 3633976 CBKinase1_024162 Cc1cc(C)n(n1)C(=O)Cn2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M07 compound treatment 3874728.0 133000.0 0.11 4037107.0 362000.0 0.29 0.2829 0.9149 3633977 CBKinase1_024163 Oc1ccccc1c2nnc(SCC(=O)Nc3ccc(Oc4ccccc4)cc3)n2c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M08 compound treatment 4050373.0 308000.0 0.26 4120188.0 445000.0 0.35 0.4345 0.9884 3633978 CBKinase1_024164 Cn1c(SCc2nc(no2)c3ccc(Cl)cc3)nnc1c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M09 mock treatment 4134816.0 393000.0 0.33 4639450.0 964000.0 0.77 0.7775 0.9292 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M10 mock treatment 4402133.0 660000.0 0.56 4405559.0 730000.0 0.58 0.8052 0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M11 compound treatment 4176429.0 434000.0 0.37 4371074.0 696000.0 0.55 0.6511 0.9797 3633979 CBKinase1_024165 C(Cn1c(NCc2ccco2)nc3ccccc13)N4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M12 compound treatment 4465438.0 723000.0 0.61 4215184.0 540000.0 0.43 0.7356 0.9854 3633980 CBKinase1_024166 CC(C(=O)Nc1sc2CCCCc2c1C#N)n3nc(C)c([N+](=O)[O-])c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M13 mock treatment 4407644.0 665000.0 0.56 4332093.0 657000.0 0.52 0.767 0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M14 mock treatment 5090369.0 1350000.0 1.14 5057290.0 1380000.0 1.1 1.583 0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M15 compound treatment 4268216.0 526000.0 0.44 4245099.0 570000.0 0.45 0.6349 0.9999 3633981 CBKinase1_024167 CCOC(=O)c1nnn(c1C)c2nonc2n3cccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M16 compound treatment 4517409.0 775000.0 0.65 4671099.0 996000.0 0.79 1.0236 0.9954 3633982 CBKinase1_024168 Oc1cc(nc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M17 compound treatment 3456629.0 -286000.0 -0.24 4760261.0 1080000.0 0.86 0.4411 0.4914 3633983 CBKinase1_024169 CCCCn1c2ccccc2c3nnc(SCC(=O)c4ccc(Cl)cc4)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M18 compound treatment 4710819.0 969000.0 0.82 4807082.0 1130000.0 0.9 1.2156 0.9988 3633984 CBKinase1_024170 [O-][N+](=O)c1ccc(OCC(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M19 compound treatment 3616208.0 -126000.0 -0.11 2024085.0 -1650000.0 -1.32 -1.0058 -0.7617 3633985 CBKinase1_024171 [O-][N+](=O)c1nn(c2ccccc2)[n+]([O-])c1NC3CCN(Cc4ccccc4)CC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M20 compound treatment 4994544.0 1250000.0 1.06 3594342.0 -81000.0 -0.06 0.7013 0.6626 3633986 CBKinase1_024172 Cc1ccc(cc1NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M21 compound treatment 4800360.0 1060000.0 0.89 5237948.0 1560000.0 1.25 1.5118 0.9867 3633987 CBKinase1_024173 COc1ccc(Cc2nnc(SCc3nc4ccccc4c(=O)[nH]3)n2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M22 compound treatment 4581781.0 840000.0 0.71 4954856.0 1280000.0 1.02 1.2219 0.9841 3633988 CBKinase1_024174 COc1ccc(cc1OC)c2cc(nc(SCC(=O)Nc3ccc4CCCc4c3)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M23 compound treatment 4238455.0 496000.0 0.42 4601184.0 926000.0 0.74 0.8178 0.9639 3633989 CBKinase1_024175 Cc1cc(C)n2nc(SCC(=O)c3cccs3)nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 M24 compound treatment 3580324.0 -162000.0 -0.14 4165500.0 490000.0 0.39 0.1797 0.4343 3633990 CBKinase1_024176 FC(F)c1cc(nc2c(cnn12)C(=O)NCc3ccco3)C4CC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N01 compound treatment 3575169.0 -167000.0 -0.14 3520320.0 -155000.0 -0.12 -0.187 -0.9979 3633991 CBKinase1_024177 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nnc(o2)c3cc(OC)cc(OC)c3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N02 compound treatment 3188461.0 -554000.0 -0.47 3183214.0 -492000.0 -0.39 -0.6076 -0.9962 3633992 CBKinase1_024178 CCn1cnc2cc(NCc3nc4ccccc4n3C)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N03 compound treatment 3852485.0 110000.0 0.09 4242757.0 567000.0 0.45 0.3856 0.8351 3633993 CBKinase1_024179 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N04 compound treatment 3960403.0 218000.0 0.18 4441994.0 767000.0 0.61 0.5622 0.881 3633994 CBKinase1_024180 Cc1cccc(NC(=O)CCc2nc(no2)c3ccccc3C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N05 compound treatment 4401074.0 659000.0 0.56 4015124.0 340000.0 0.27 0.5845 0.9454 3633995 CBKinase1_024181 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc(cc2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N06 compound treatment 4536666.0 794000.0 0.67 4649670.0 974000.0 0.78 1.023 0.9973 3633996 CBKinase1_024182 COc1ccc(CCNC(=O)c2nn3c(cc(nc3c2Cl)c4ccccc4)C(F)(F)F)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N07 compound treatment 4119572.0 377000.0 0.32 4368923.0 694000.0 0.55 0.616 0.9656 3633997 CBKinase1_024183 COc1cc(ccc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N08 compound treatment 3893366.0 151000.0 0.13 4066582.0 391000.0 0.31 0.3107 0.9222 3633998 CBKinase1_024184 O=C1N(CCSc2nc(c(C#N)c(=O)[nH]2)c3ccccc3)C(=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N09 mock treatment 4315299.0 573000.0 0.48 4575972.0 901000.0 0.72 0.8494 0.9815 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N10 mock treatment 4531573.0 789000.0 0.67 3921492.0 246000.0 0.2 0.6095 0.8781 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N11 compound treatment 3950837.0 209000.0 0.18 6169845.0 2490000.0 1.99 1.5303 0.7667 3633999 CBKinase1_024185 CCn1c(SCc2nc(no2)c3cccs3)nnc1c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N12 compound treatment 4172593.0 430000.0 0.36 4052228.0 377000.0 0.3 0.4691 0.9956 1346549 CBKinase1_024186 CC1=C(C(c2ccccc2OCc3ccccc3)n4nnnc4N1)C(=O)Nc5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N13 mock treatment 4141123.0 399000.0 0.34 4637111.0 962000.0 0.77 0.78 0.9317 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N14 mock treatment 4086049.0 344000.0 0.29 4666103.0 991000.0 0.79 0.7635 0.9076 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N15 compound treatment 4207882.0 466000.0 0.39 4491926.0 817000.0 0.65 0.738 0.9708 3634000 CBKinase1_024187 Oc1cc(Cl)ccc1NC(=O)CSc2nnnn2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N16 compound treatment 4263997.0 522000.0 0.44 4810176.0 1130000.0 0.9 0.9508 0.9452 3634001 CBKinase1_024188 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cncc(Br)c3)cc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N17 compound treatment 4424401.0 682000.0 0.58 5131982.0 1460000.0 1.16 1.2279 0.9476 3634002 CBKinase1_024189 C(c1nnc2sc(/C=C/c3ccccc3)nn12)n4cnc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N18 compound treatment 4353949.0 612000.0 0.52 4389039.0 714000.0 0.57 0.7671 0.9988 3634004 CBKinase1_024190 CN(C)S(=O)(=O)N(CC(=O)Nc1c(C)cc(C)cc1C)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N19 compound treatment 5092812.0 1350000.0 1.14 5024187.0 1350000.0 1.08 1.5658 0.9996 3634005 CBKinase1_024191 NC(=O)c1c(NC(=O)c2cnn3c(cc(nc23)c4cccs4)C(F)(F)F)sc5CCCCc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N20 compound treatment 3216152.0 -526000.0 -0.44 4375515.0 700000.0 0.56 0.0809 0.1134 3634006 CBKinase1_024192 COc1ccc(cc1)c2noc(CSc3nnc(c4ccccc4)n3C)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N21 compound treatment 5073142.0 1330000.0 1.12 5331748.0 1660000.0 1.32 1.7274 0.9967 3634007 CBKinase1_024193 Cc1ccc(NC(=O)CCCn2cc(cn2)[N+](=O)[O-])cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N22 compound treatment 4710137.0 968000.0 0.82 4952411.0 1280000.0 1.02 1.2971 0.994 3634008 CBKinase1_024194 CN(CC(=O)Nc1cccc2CCCCc12)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N23 compound treatment 4330681.0 589000.0 0.5 4272313.0 597000.0 0.48 0.6875 0.9998 3634009 CBKinase1_024195 Cc1cc(ccc1F)S(=O)(=O)Nc2c(C)nc3ncnn3c2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 N24 compound treatment 3872088.0 130000.0 0.11 4038723.0 363000.0 0.29 0.2823 0.9116 1911451 CBKinase1_024196 COc1ccccc1NC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O01 compound treatment 3164663.0 -578000.0 -0.49 3005934.0 -669000.0 -0.53 -0.7217 -0.999 3634010 CBKinase1_024197 COc1ccc(c2ccccc12)S(=O)(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O02 compound treatment 4600103.0 858000.0 0.72 4142250.0 467000.0 0.37 0.7748 0.9522 3634011 CBKinase1_024198 [O-][N+](=O)c1ccn(CC(=O)n2cc(Br)cn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O03 compound treatment 3475246.0 -267000.0 -0.23 4794903.0 1120000.0 0.89 0.4718 0.5126 3634012 CBKinase1_024199 COc1cccc(NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O04 compound treatment 4222896.0 481000.0 0.41 4383206.0 708000.0 0.56 0.6857 0.9869 3634013 CBKinase1_024200 CSc1ncc(Cl)c(n1)C(=O)Nc2nnc(SCc3ccccc3)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O05 compound treatment 4030883.0 289000.0 0.24 4706884.0 1030000.0 0.82 0.7536 0.8788 3634014 CBKinase1_024201 Cc1nnc(SCC(=O)n2c3CCCCc3c4ccccc24)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O06 compound treatment 3564028.0 -178000.0 -0.15 4081995.0 407000.0 0.32 0.1229 0.3441 3634015 CBKinase1_024202 Oc1ccccc1C(=O)CC2(O)C(=O)N(Cc3ccccc3Cl)c4ccc(Cl)cc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O07 compound treatment 2874490.0 -868000.0 -0.73 2921042.0 -754000.0 -0.6 -0.9427 -0.9952 3634016 CBKinase1_024203 Cn1c(SCC(=O)Nc2ccccc2C(=O)Nc3ccccc3)nc4ccccc4c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O08 compound treatment 4008463.0 266000.0 0.22 4125484.0 450000.0 0.36 0.4125 0.9746 1788890 CBKinase1_024204 Cc1nn(Cc2ccc(C)cc2)c(C)c1NC(=O)c3nc4ncccn4n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O09 compound treatment 3895650.0 153000.0 0.13 4186363.0 511000.0 0.41 0.3795 0.8881 3634017 CBKinase1_024205 COc1ccc(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O10 compound treatment 4388792.0 647000.0 0.55 3632285.0 -43100.0 -0.03 0.3614 0.6613 3634018 CBKinase1_024206 COc1ccccc1NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O11 mock treatment 4053087.0 311000.0 0.26 3865123.0 190000.0 0.15 0.2924 0.9658 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O12 mock treatment 4484338.0 742000.0 0.63 4853251.0 1180000.0 0.94 1.1065 0.9806 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O13 compound treatment 4346339.0 604000.0 0.51 5012194.0 1340000.0 1.07 1.1138 0.943 1984675 CBKinase1_024207 CCOc1ccc(cc1S(=O)(=O)NCc2ccccc2)n3cnnn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O14 compound treatment 4364689.0 623000.0 0.53 4636697.0 961000.0 0.77 0.9131 0.983 3634019 CBKinase1_024208 COc1ccc(C)cc1NC(=O)CSc2nc(C)cc(n2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O15 compound treatment 4188137.0 446000.0 0.38 4868418.0 1190000.0 0.95 0.9384 0.9176 3634020 CBKinase1_024209 COc1ccc(cc1NC(=O)COc2ccccc2[N+](=O)[O-])c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O16 compound treatment 4589003.0 847000.0 0.71 5073914.0 1400000.0 1.11 1.2933 0.9769 3634021 CBKinase1_024210 OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4Cl)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O17 compound treatment 5186037.0 1440000.0 1.22 5495400.0 1820000.0 1.45 1.8869 0.9962 3634022 CBKinase1_024211 CCc1c(C)nc(SCC(=O)Nc2ccc(OC)cc2)nc1O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O18 compound treatment 4610856.0 869000.0 0.73 4241541.0 566000.0 0.45 0.8372 0.9729 3634023 CBKinase1_024212 COc1ccc(C)cc1NC(=O)CN2C(=O)CN(C2=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O19 compound treatment 6050919.0 2310000.0 1.95 5724727.0 2050000.0 1.63 2.532 0.9962 3634024 CBKinase1_024213 O=c1[nH]c(SCc2n[nH]c(=S)n2c3ccccc3)nc4sc5CCCc5c14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O20 compound treatment 5425172.0 1680000.0 1.42 5706844.0 2030000.0 1.62 2.1487 0.9979 3634025 CBKinase1_024214 Fc1ccc(cc1)c2nnc(SCCCN3C(=O)c4cccc5cccc(C3=O)c45)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O21 compound treatment 5377038.0 1630000.0 1.38 5589780.0 1910000.0 1.53 2.0541 0.9987 3634026 CBKinase1_024215 CCN(CC(=O)Nc1ccccc1C)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O22 compound treatment 4989460.0 1250000.0 1.05 5114023.0 1440000.0 1.15 1.5548 0.9991 3634027 CBKinase1_024216 CC1CCc2c(C1)c3ccccc3n2C(=O)CSc4nccc(C)n4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O23 compound treatment 4755735.0 1010000.0 0.85 4781339.0 1110000.0 0.88 1.2279 0.9999 3634028 CBKinase1_024217 CCOC(=O)c1ccc(CNC(=O)c2n[nH]c(=O)c3ccccc23)o1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 O24 compound treatment 3674884.0 -67300.0 -0.06 3886914.0 212000.0 0.17 0.0791 0.4446 3634029 CBKinase1_024218 CN(C)c1nc(Nc2ccc(C)cc2)nc(Oc3ccc(OCc4ccccc4)nn3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P01 compound treatment 2037084.0 -1710000.0 -1.44 2822269.0 -853000.0 -0.68 -1.4978 -0.9415 3634030 CBKinase1_024219 COc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccccc3)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P02 compound treatment 3144745.0 -597000.0 -0.5 2929781.0 -746000.0 -0.59 -0.7765 -0.9966 3634031 CBKinase1_024220 CCC1(CC)C(=O)N=C(SCC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)N(C)C1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P03 compound treatment 2998365.0 -744000.0 -0.63 3479520.0 -196000.0 -0.16 -0.554 -0.8569 3634032 CBKinase1_024221 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1F)c2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P04 compound treatment 4053588.0 311000.0 0.26 4561614.0 886000.0 0.71 0.6852 0.9092 3634033 CBKinase1_024222 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2C(=O)N3CCCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P05 compound treatment 4270040.0 528000.0 0.45 3720423.0 45100.0 0.04 0.3402 0.7617 3634034 CBKinase1_024223 CN(Cc1nc(no1)c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P06 compound treatment 3245774.0 -496000.0 -0.42 4711178.0 1040000.0 0.83 0.2877 0.3108 3634035 CBKinase1_024224 CCC(N1C(=O)c2ccccc2C1=O)c3nc4ccccc4c(=O)n3c5ccccn5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P07 compound treatment 3051643.0 -691000.0 -0.58 3692883.0 17500.0 0.01 -0.402 -0.69 3634036 CBKinase1_024225 CCN(CC(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P08 compound treatment 3544320.0 -198000.0 -0.17 3642372.0 -33000.0 -0.03 -0.1366 -0.8086 3634037 CBKinase1_024226 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P09 compound treatment 999613.0 -2740000.0 -2.31 1171112.0 -2500000.0 -2.0 -3.0472 -0.9973 3634038 CBKinase1_024227 Oc1c(ccc2cccnc12)C(Nc3cccnc3)c4ccc(cc4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P10 compound treatment 2962130.0 -780000.0 -0.66 2796520.0 -879000.0 -0.7 -0.9606 -0.9995 3634039 CBKinase1_024228 Cc1ccccc1NC(=O)CCc2nc(no2)c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P11 mock treatment 3658575.0 -83600.0 -0.07 3418121.0 -257000.0 -0.21 -0.1948 -0.8986 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P12 mock treatment 3790956.0 48800.0 0.04 4339754.0 664000.0 0.53 0.4035 0.7598 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P13 compound treatment 3954293.0 212000.0 0.18 3704395.0 29000.0 0.02 0.1429 0.792 3634040 CBKinase1_024229 CCn1c(SCC(=O)Nc2ccccc2F)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P14 compound treatment 3926640.0 184000.0 0.16 4125704.0 450000.0 0.36 0.3638 0.93 3634041 CBKinase1_024230 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)c(Cl)c1)c2ccc(F)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P15 compound treatment 4010953.0 269000.0 0.23 4322238.0 647000.0 0.52 0.5249 0.9319 3634042 CBKinase1_024231 COc1ccc(CNCCSc2nnnn2C)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P16 compound treatment 4456617.0 714000.0 0.6 4269156.0 594000.0 0.47 0.7608 0.9928 3634043 CBKinase1_024232 COC(=O)c1cccc(NC(=O)COc2ccc(I)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P17 compound treatment 4183657.0 441000.0 0.37 4705420.0 1030000.0 0.82 0.8439 0.936 3634044 CBKinase1_024233 Cc1cc(C)cc(NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P18 compound treatment 4074468.0 332000.0 0.28 4402172.0 727000.0 0.58 0.6078 0.9445 3634045 CBKinase1_024234 NC(=O)CSc1oc(nc1S(=O)(=O)c2ccccc2)c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P19 compound treatment 2949402.0 -793000.0 -0.67 3245777.0 -430000.0 -0.34 -0.715 -0.9517 3634046 CBKinase1_024235 COc1ccccc1CNc2c(nn(c3ccccc3)[n+]2[O-])[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P20 compound treatment 4859037.0 1120000.0 0.94 4957700.0 1280000.0 1.02 1.3889 0.9992 3634047 CBKinase1_024236 OC(=O)Cc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P21 compound treatment 4937443.0 1200000.0 1.01 5973729.0 2300000.0 1.83 2.0083 0.9604 3634048 CBKinase1_024237 COc1ccc(NS(=O)(=O)c2ccc3oc4ccccc4c3c2)cn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P22 compound treatment 4384595.0 642000.0 0.54 4739118.0 1060000.0 0.85 0.9827 0.9766 3634049 CBKinase1_024238 CN(Cc1nc(no1)c2ccccn2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P23 compound treatment 4574552.0 832000.0 0.7 4816048.0 1140000.0 0.91 1.1394 0.9918 3123891 CBKinase1_024239 Cn1c(CN2CCOCC2)nc3cc(NS(=O)(=O)c4ccc(F)cc4)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2399 P24 compound treatment 3557598.0 -185000.0 -0.16 3724244.0 48900.0 0.04 -0.0825 -0.5143 3634050 CBKinase1_024240 COc1ccccc1CC(=O)Nc2cc(Cl)ccc2O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A01 compound treatment 1760924.0 -1780000.0 -1.5 1273063.0 -2120000.0 -1.69 -2.2555 -0.9981 3634051 CBKinase1_024241 Oc1c(ccc2cccnc12)C(Nc3cccnc3)c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A02 compound treatment 3898227.0 362000.0 0.31 1788482.0 -1610000.0 -1.28 -0.6903 -0.5239 3634052 CBKinase1_024242 Brc1cccc(NC(=O)CSc2nnnn2c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A03 compound treatment 2851259.0 -685000.0 -0.58 3128770.0 -268000.0 -0.21 -0.5593 -0.9083 3634053 CBKinase1_024243 Oc1c(ccc2cccnc12)C(Nc3cccnc3)c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A04 compound treatment 3270066.0 -266000.0 -0.22 2351340.0 -1050000.0 -0.83 -0.7477 -0.8667 3634054 CBKinase1_024244 Fc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A05 compound treatment 3467430.0 -68700.0 -0.06 3474973.0 78500.0 0.06 0.0033 0.0385 3634055 CBKinase1_024245 COC(=O)c1ccccc1NC(=O)c2cccc(NC(=O)COc3ccccc3)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A06 compound treatment 3575306.0 39200.0 0.03 2783206.0 -613000.0 -0.49 -0.3222 -0.6578 3634056 CBKinase1_024246 CCn1cnc2cc(NCc3cccc(OC)c3O)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A07 compound treatment 2977554.0 -559000.0 -0.47 2878222.0 -518000.0 -0.41 -0.6252 -0.9978 3634057 CBKinase1_024247 CCn1c(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A08 compound treatment 3446326.0 -89800.0 -0.08 2927262.0 -469000.0 -0.37 -0.318 -0.8334 3634058 CBKinase1_024248 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(NC(=O)COc3ccc(cc3)[N+](=O)[O-])cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A09 compound treatment 3193907.0 -342000.0 -0.29 3436061.0 39600.0 0.03 -0.1818 -0.626 3634059 CBKinase1_024249 COc1cccc(NC(=O)CNC(=O)c2ccco2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A10 compound treatment 3352844.0 -183000.0 -0.15 2902443.0 -494000.0 -0.39 -0.3877 -0.9166 1189748 CBKinase1_024250 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)c4nc5ccccc5o4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A11 compound treatment 3445477.0 -90600.0 -0.08 3330773.0 -65700.0 -0.05 -0.0911 -0.9829 3634060 CBKinase1_024251 COc1ccc(OC)c(NC(=O)CSc2nc(N)c(c3ccccc3)c(=O)[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A12 compound treatment 3447228.0 -88900.0 -0.07 3471376.0 74900.0 0.06 -0.0108 -0.1126 3634061 CBKinase1_024252 CCOC(=O)c1c(NC(=O)C(C)Oc2ccccc2C)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A13 mock treatment 3530238.0 -5890.0 0.0 3157594.0 -239000.0 -0.19 -0.1381 -0.7253 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A14 mock treatment 3411091.0 -125000.0 -0.11 3417962.0 21500.0 0.02 -0.0624 -0.5844 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A15 compound treatment 3151437.0 -385000.0 -0.32 3385951.0 -10500.0 -0.01 -0.2354 -0.7251 3634062 CBKinase1_024253 COc1ccc2NC(=O)C(O)(CC(=O)c3ccc4ccccc4c3)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A16 compound treatment 3410422.0 -126000.0 -0.11 3478338.0 81900.0 0.07 -0.0288 -0.2315 3634063 CBKinase1_024254 COc1cc(ccc1NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A17 compound treatment 3611636.0 75500.0 0.06 3329339.0 -67100.0 -0.05 0.0072 0.0868 3634064 CBKinase1_024255 Cc1cccc(c1)C(=O)Nc2cccc(OCC(=O)O)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A18 compound treatment 3310007.0 -226000.0 -0.19 3457784.0 61300.0 0.05 -0.1003 -0.5094 3634065 CBKinase1_024256 Cc1nnc2sc(nn12)c3ccccc3NC(=S)NC(=O)CC4(CC5CC6CC(C5)C4)C6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A19 compound treatment 3719930.0 184000.0 0.16 3488338.0 91900.0 0.07 0.1614 0.9414 3634066 CBKinase1_024257 COc1ccc(cc1OC)C(=O)CC2(O)C(=O)N(Cc3ccc(Cl)c(Cl)c3)c4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A20 compound treatment 3685531.0 149000.0 0.13 3676894.0 280000.0 0.22 0.2472 0.9632 3634067 CBKinase1_024258 COc1cc(OC)cc(c1)c2nnc(SCC(=O)NC3CC4CCC3C4)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A21 compound treatment 3151195.0 -385000.0 -0.32 3487157.0 90700.0 0.07 -0.1785 -0.5365 3634068 CBKinase1_024259 Cc1c(sc2ncn(CC(=O)Nc3cc(ccc3Cl)C(F)(F)F)c(=O)c12)C(=O)Nc4ccc(C)cc4C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A22 compound treatment 3479571.0 -56600.0 -0.05 3446756.0 50300.0 0.04 -0.0054 -0.0862 3634069 CBKinase1_024260 Cc1cc(OCC(=O)NCc2cccnc2)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A23 compound treatment 3138600.0 -398000.0 -0.34 3151411.0 -245000.0 -0.2 -0.3752 -0.9669 3634070 CBKinase1_024261 OC(=O)CC(C(=O)O)c1ccc(Cl)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 A24 compound treatment 2491879.0 -1040000.0 -0.88 2721951.0 -674000.0 -0.54 -1.003 -0.972 3634071 CBKinase1_024262 CCn1c(SCC(=O)c2c[nH]c3ccccc23)nnc1c4cccs4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B01 compound treatment 2528858.0 -1010000.0 -0.85 3008864.0 -388000.0 -0.31 -0.8192 -0.9062 3634072 CBKinase1_024263 O=C(CN1C(=O)C2C(C3C=CC2C4CC43)C1=O)Nc5ccc(Oc6ccccc6)cc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B02 compound treatment 3675615.0 139000.0 0.12 4066499.0 670000.0 0.53 0.4608 0.8427 3634073 CBKinase1_024264 Cc1ccc(C)c(NC(=O)Cn2cc(cn2)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B03 compound treatment 3652350.0 116000.0 0.1 3001616.0 -395000.0 -0.31 -0.1532 -0.4648 3634074 CBKinase1_024265 COC(=O)c1cccc(NC(=O)CSc2nc(C)c3CCCCc3n2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B04 compound treatment 4603220.0 1070000.0 0.9 3577357.0 181000.0 0.14 0.7384 0.8101 3634075 CBKinase1_024266 OC(=O)CCSc1nnc(c2ccncc2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B05 compound treatment 5223774.0 1690000.0 1.42 3350633.0 -45800.0 -0.04 0.9808 0.6887 3634076 CBKinase1_024267 CN(CC(=O)Nc1ccccc1C(=O)N2CCCC2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B06 compound treatment 3808497.0 272000.0 0.23 3660360.0 264000.0 0.21 0.3112 0.999 3634077 CBKinase1_024268 Cc1ccc(F)cc1NC(=O)CCCSc2nc(cc(n2)C(F)(F)F)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B07 compound treatment 3068247.0 -468000.0 -0.39 3034466.0 -362000.0 -0.29 -0.4831 -0.9881 3634078 CBKinase1_024269 COC(=O)c1cc(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B08 compound treatment 4034864.0 499000.0 0.42 3415518.0 19100.0 0.02 0.3082 0.7322 3634079 CBKinase1_024270 CCOC(=O)c1cnc(SCC(=O)Nc2ccccc2C)nc1N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B09 compound treatment 3836816.0 301000.0 0.25 3512964.0 117000.0 0.09 0.245 0.9071 3634080 CBKinase1_024271 CC(=O)Oc1ccc(cc1)C(=O)NCc2nc(no2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B10 compound treatment 4069370.0 533000.0 0.45 3955445.0 559000.0 0.45 0.6331 1.0 3634081 CBKinase1_024272 COc1ccc(NC(=O)Cn2cnc3sc4CC(C)CCc4c3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B11 compound treatment 3424721.0 -111000.0 -0.09 3425111.0 28700.0 0.02 -0.0503 -0.52 3634082 CBKinase1_024273 CCN(CC(=O)Nc1cccc(C)c1)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B12 compound treatment 4128640.0 593000.0 0.5 4015549.0 619000.0 0.49 0.7023 1.0 3634083 CBKinase1_024274 CC(CC(=O)O)n1nc(C)c(C(=O)C)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B13 mock treatment 4088131.0 552000.0 0.47 4070003.0 674000.0 0.54 0.7089 0.9975 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B14 mock treatment 3912045.0 376000.0 0.32 3827502.0 431000.0 0.34 0.4672 0.9992 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B15 compound treatment 4082708.0 547000.0 0.46 3808249.0 412000.0 0.33 0.5581 0.9861 3634084 CBKinase1_024275 CC(C)c1ccc(NC(=O)Cn2cc(cn2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B16 compound treatment 4075930.0 540000.0 0.46 3759984.0 364000.0 0.29 0.5269 0.9762 3634085 CBKinase1_024276 Sc1nnc(Cn2ncc3ccccc3c2=O)n1c4ccc5OCCOc5c4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B17 compound treatment 3931515.0 395000.0 0.33 3770662.0 374000.0 0.3 0.4467 0.9984 3634086 CBKinase1_024277 O=C(CSc1nc2ccccc2o1)N3N=CCC3c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B18 compound treatment 3897652.0 362000.0 0.3 3756374.0 360000.0 0.29 0.4185 0.9995 3634087 CBKinase1_024278 CSc1ncc(Cl)c(n1)C(=O)Nc2sc3CCCc3c2C(=O)NCc4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B19 compound treatment 4163123.0 627000.0 0.53 3073201.0 -323000.0 -0.26 0.1918 0.326 3634088 CBKinase1_024279 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B20 compound treatment 4139205.0 603000.0 0.51 4237207.0 841000.0 0.67 0.8336 0.9908 3634089 CBKinase1_024280 [O-][N+](=O)c1ccn(CC(=O)NCc2ccco2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B21 compound treatment 2427419.0 -1110000.0 -0.94 2722551.0 -674000.0 -0.54 -1.0411 -0.9653 3634090 CBKinase1_024281 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)C(C)(C)Oc3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B22 compound treatment 4431929.0 896000.0 0.76 4410585.0 1010000.0 0.81 1.1059 0.9994 3634091 CBKinase1_024282 OC(=O)c1cccc(NC(=O)CSc2nnc(c3cccs3)n2c4ccccc4Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B23 compound treatment 3649609.0 113000.0 0.1 3846520.0 450000.0 0.36 0.3213 0.8655 3634092 CBKinase1_024283 COc1cc(C)c(Cl)cc1S(=O)(=O)NCCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 B24 compound treatment 2506607.0 -1030000.0 -0.87 2794139.0 -602000.0 -0.48 -0.9535 -0.9609 3634093 CBKinase1_024284 Cn1c(SCCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1c5cccs5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C01 compound treatment 2664701.0 -871000.0 -0.74 2822658.0 -574000.0 -0.46 -0.8431 -0.9739 3634094 CBKinase1_024285 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=S)NC(=O)c3cc4ccccc4o3)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C02 compound treatment 2671528.0 -865000.0 -0.73 2792093.0 -604000.0 -0.48 -0.8563 -0.9797 3634095 CBKinase1_024286 [O-][N+](=O)c1ccc(NC(=O)CCc2nc(no2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C03 compound treatment 3192371.0 -344000.0 -0.29 3117536.0 -279000.0 -0.22 -0.3622 -0.9914 3634096 CBKinase1_024287 CCn1c(SCC(=O)O)nnc1c2c[nH]c3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C04 compound treatment 3261377.0 -275000.0 -0.23 3151589.0 -245000.0 -0.2 -0.3019 -0.9963 3634097 CBKinase1_024288 Oc1cc(=O)nc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C05 compound treatment 3469758.0 -66400.0 -0.06 3952072.0 556000.0 0.44 0.2736 0.6128 3634098 CBKinase1_024289 Clc1ccc2oc(cc2c1)c3nnc(SCc4nc5ccccc5c(=O)[nH]4)n3CC=C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C06 compound treatment 3244963.0 -291000.0 -0.25 3291315.0 -105000.0 -0.08 -0.2329 -0.8976 3634099 CBKinase1_024290 Cc1ccc(c(C)c1NS(=O)(=O)C)S(=O)(=O)Nc2ccc3OCCOc3c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C07 compound treatment 3195437.0 -341000.0 -0.29 3523954.0 128000.0 0.1 -0.1313 -0.4309 3634100 CBKinase1_024291 COc1ccc(C(=O)CC2(O)C(=O)N(CCCC#N)c3ccccc32)c(OC)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C08 compound treatment 3342770.0 -193000.0 -0.16 3548004.0 152000.0 0.12 -0.0299 -0.1473 3634101 CBKinase1_024292 COC(=O)c1ccccc1NC(=O)COc2cc(C)c(Br)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C09 compound treatment 3237172.0 -299000.0 -0.25 3491122.0 94700.0 0.08 -0.1249 -0.4747 3634102 CBKinase1_024293 COC(=O)c1ccc(Cl)c(NC(=O)CN2CCN(C)CC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C10 compound treatment 3442023.0 -94100.0 -0.08 3565648.0 169000.0 0.13 0.0392 0.2507 3634103 CBKinase1_024294 CN(CC(=O)Nc1ccc(cc1)C(=O)C)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C11 mock treatment 3548194.0 12100.0 0.01 3384325.0 -12100.0 -0.01 4.0E-4 0.0263 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C12 mock treatment 3570379.0 34300.0 0.03 3511547.0 115000.0 0.09 0.0853 0.8869 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C13 compound treatment 3267621.0 -269000.0 -0.23 3459744.0 63300.0 0.05 -0.1245 -0.5364 3634104 CBKinase1_024295 COc1ccc(Cl)cc1C(Nc2cccnc2)c3ccc4cccnc4c3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C14 compound treatment 3823892.0 288000.0 0.24 3507283.0 111000.0 0.09 0.2341 0.9063 3634105 CBKinase1_024296 COc1ccc(NC(=O)CNC(=O)c2ccccc2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C15 mock treatment 3903020.0 367000.0 0.31 3556994.0 161000.0 0.13 0.3093 0.9236 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C16 mock treatment 3772994.0 237000.0 0.2 3626300.0 230000.0 0.18 0.2708 0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C17 compound treatment 3340294.0 -196000.0 -0.17 3657674.0 261000.0 0.21 0.0304 0.1145 3634106 CBKinase1_024297 COc1ccc(OC)c(NC(=O)COc2cc(C)c(Br)cc2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C18 compound treatment 3503800.0 -32300.0 -0.03 3946438.0 550000.0 0.44 0.2907 0.6618 3634107 CBKinase1_024298 COC(=O)c1cccc(NC(=O)CSc2nc(C)cc(n2)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C19 compound treatment 3784138.0 248000.0 0.21 3852335.0 456000.0 0.36 0.4049 0.9656 3634108 CBKinase1_024299 Cc1cccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cncc(Br)c4)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C20 compound treatment 3679596.0 143000.0 0.12 3719502.0 323000.0 0.26 0.2676 0.9407 3634109 CBKinase1_024300 Cc1c(Cl)cccc1NC(=O)CNC(=O)c2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C21 compound treatment 3517264.0 -18900.0 -0.02 3727198.0 331000.0 0.26 0.1752 0.6632 3634110 CBKinase1_024301 Cc1ccc(cc1)S(=O)(=O)NCCSc2nc(c[nH]2)c3ccc(cc3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C22 compound treatment 3485651.0 -50500.0 -0.04 3700288.0 304000.0 0.24 0.1411 0.574 3634111 CBKinase1_024302 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(F)cc2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C23 compound treatment 2963502.0 -573000.0 -0.48 3292037.0 -104000.0 -0.08 -0.4004 -0.8169 3634112 CBKinase1_024303 O=c1n(CCN2CCOCC2)c(nc3ccccc13)c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 C24 compound treatment 2689493.0 -847000.0 -0.71 2921338.0 -475000.0 -0.38 -0.7727 -0.956 3634113 CBKinase1_024304 COc1ccc(OCC(=O)Nc2ccc(NC(=O)c3ccccc3Cl)c(OC)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D01 compound treatment 2670994.0 -865000.0 -0.73 2317149.0 -1080000.0 -0.86 -1.1243 -0.9966 3634114 CBKinase1_024305 CC(C(=O)Nc1ccc(C)c(Cl)c1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D02 compound treatment 2978313.0 -558000.0 -0.47 3260076.0 -136000.0 -0.11 -0.4096 -0.8481 3634115 CBKinase1_024306 CCCC1=C(C(c2cccnc2)n3nc(C)nc3N1)C(=O)OCC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D03 compound treatment 3397460.0 -139000.0 -0.12 3543309.0 147000.0 0.12 1.0E-4 4.0E-4 3634116 CBKinase1_024307 CCn1c(SCC(=O)Nc2ccccc2OC)nnc1c3c[nH]c4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D04 compound treatment 3262337.0 -274000.0 -0.23 3805841.0 409000.0 0.33 0.0674 0.1687 3634117 CBKinase1_024308 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D05 compound treatment 3721515.0 185000.0 0.16 3483465.0 87000.0 0.07 0.1596 0.9331 3634118 CBKinase1_024309 COc1ccc(NC(=O)CNC(=O)c2ccc(F)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D06 compound treatment 3186825.0 -349000.0 -0.29 3671327.0 275000.0 0.22 -0.0534 -0.1455 3634119 CBKinase1_024310 COc1ccc(Cl)cc1NC(=O)C(C)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D07 compound treatment 3220240.0 -316000.0 -0.27 3561914.0 165000.0 0.13 -0.0951 -0.32 3634120 CBKinase1_024311 COc1cc(ccc1NC(=O)CN2CCOCC2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D08 compound treatment 3719587.0 183000.0 0.15 3700696.0 304000.0 0.24 0.2809 0.9765 3634121 CBKinase1_024312 CSc1ccccc1NC(=O)Cn2ccc(n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D09 compound treatment 3822111.0 286000.0 0.24 3957388.0 561000.0 0.45 0.4867 0.9581 3634122 CBKinase1_024313 COc1cc(ccc1NC(=O)CSc2ncccn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D10 compound treatment 3856238.0 320000.0 0.27 4001975.0 606000.0 0.48 0.5322 0.9623 3634123 CBKinase1_024314 CC(C(=O)NCC1CCCO1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D11 mock treatment 3744785.0 209000.0 0.18 4050438.0 654000.0 0.52 0.493 0.8962 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D12 mock treatment 4008698.0 473000.0 0.4 3703933.0 307000.0 0.25 0.4552 0.9727 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D13 compound treatment 3667247.0 131000.0 0.11 3684647.0 288000.0 0.23 0.2406 0.9439 3634124 CBKinase1_024315 CC(C)c1ccc(C)cc1OCC(=O)Nc2cccc3ncccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D14 compound treatment 3695563.0 159000.0 0.13 3695520.0 299000.0 0.24 0.2637 0.9633 1954570 CBKinase1_024316 COc1ccc(cc1OC)C2CC(n3ncc(C(=O)Nc4sc5CC(C)CCc5c4C#N)c3N2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D15 mock treatment 3971657.0 436000.0 0.37 4048799.0 652000.0 0.52 0.6274 0.9855 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D16 mock treatment 4037393.0 501000.0 0.42 4101698.0 705000.0 0.56 0.6965 0.9901 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D17 compound treatment 3982523.0 446000.0 0.38 3905540.0 509000.0 0.41 0.5532 0.9993 3634125 CBKinase1_024317 Cc1ccc(Nc2nc(Oc3ccc(O)nn3)nc(n2)N4CCOCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D18 compound treatment 3789414.0 253000.0 0.21 3739001.0 343000.0 0.27 0.3441 0.9926 3634126 CBKinase1_024318 COc1ccc(CCNC(=O)c2cc3cc(Br)cc(OC)c3oc2=O)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D19 compound treatment 3724398.0 188000.0 0.16 4077075.0 681000.0 0.54 0.4959 0.8773 3634127 CBKinase1_024319 Cn1c2ccccc2c3nnc(Sc4ccc5nsnc5c4[N+](=O)[O-])nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D20 compound treatment 3762474.0 226000.0 0.19 4296427.0 900000.0 0.72 0.6422 0.8652 3634128 CBKinase1_024320 [O-][N+](=O)c1ccn(CC(=O)n2cc(I)cn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D21 compound treatment 3440091.0 -96000.0 -0.08 3141810.0 -255000.0 -0.2 -0.2008 -0.9189 3634129 CBKinase1_024321 COc1ccc(cc1)n2c(SCCCN3C(=O)c4cccc5cccc(C3=O)c45)nnc2c6cccnc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D22 compound treatment 3656156.0 120000.0 0.1 3851058.0 455000.0 0.36 0.3278 0.8713 3634130 CBKinase1_024322 Cc1ccc(c(Br)c1)n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D23 compound treatment 3605298.0 69200.0 0.06 3629899.0 233000.0 0.19 0.1728 0.8863 3634131 CBKinase1_024323 O=C(CSc1nc(Nc2ccccc2)nc(n1)N3CCOCC3)N4CCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 D24 compound treatment 2829951.0 -706000.0 -0.6 2990968.0 -405000.0 -0.32 -0.6497 -0.9587 3634132 CBKinase1_024324 Cc1ccc(C)c(NC(=O)CCCn2cc(cn2)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E01 mock treatment 1145163.0 -2390000.0 -2.02 1091268.0 -2310000.0 -1.84 -2.7253 -0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E02 mock treatment 1382421.0 -2150000.0 -1.82 1123398.0 -2270000.0 -1.81 -2.5656 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E03 compound treatment 1537006.0 -2000000.0 -1.69 1498430.0 -1900000.0 -1.51 -2.2621 -0.9985 3634133 CBKinase1_024325 COc1ccccc1NC(=O)CNC(=O)c2ccccc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E04 compound treatment 1551654.0 -1980000.0 -1.67 3334391.0 -62100.0 -0.05 -1.2186 -0.7277 3634134 CBKinase1_024326 Cc1cc(OCC(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O)cc(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E05 compound treatment 1619799.0 -1920000.0 -1.62 1593263.0 -1800000.0 -1.44 -2.1592 -0.9983 3634135 CBKinase1_024327 OC(=O)COc1cccc(NC(=O)C2CCCO2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E06 compound treatment 1872565.0 -1660000.0 -1.4 1765876.0 -1630000.0 -1.3 -1.9112 -0.9993 3634136 CBKinase1_024328 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3nc4ccccc4nc3n5nc(C)cc5C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E07 compound treatment 1657846.0 -1880000.0 -1.58 1465973.0 -1930000.0 -1.54 -2.2083 -0.9999 3634137 CBKinase1_024329 Oc1c(ccc2cccnc12)C(Nc3cccnc3)c4ccsc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E08 compound treatment 2504300.0 -1030000.0 -0.87 1818129.0 -1580000.0 -1.26 -1.505 -0.9838 3634138 CBKinase1_024330 Cc1ccc(NC(=O)c2ccco2)c(NC(=O)CN3C(=O)c4ccccc4C3=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E09 mock treatment 2335232.0 -1200000.0 -1.01 2329937.0 -1070000.0 -0.85 -1.3173 -0.9962 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E10 mock treatment 2388723.0 -1150000.0 -0.97 2121744.0 -1270000.0 -1.02 -1.4028 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E11 compound treatment 2393685.0 -1140000.0 -0.96 2303995.0 -1090000.0 -0.87 -1.2971 -0.9987 3634139 CBKinase1_024331 CCn1c(SCC(=O)N2CCOCC2)nnc1c3c[nH]c4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E12 compound treatment 2686274.0 -850000.0 -0.72 2631484.0 -765000.0 -0.61 -0.938 -0.9968 3634140 CBKinase1_024332 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cccc(F)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E13 compound treatment 2788906.0 -747000.0 -0.63 2650275.0 -746000.0 -0.59 -0.8662 -0.9996 3634141 CBKinase1_024333 Cn1c(SCc2nc(no2)c3cccs3)nnc1C4CCCCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E14 compound treatment 2565880.0 -970000.0 -0.82 2647387.0 -749000.0 -0.6 -1.0009 -0.988 3634142 CBKinase1_024334 COc1ccc(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E15 compound treatment 2910497.0 -626000.0 -0.53 2402793.0 -994000.0 -0.79 -0.9332 -0.9805 3634143 CBKinase1_024335 Cc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E16 compound treatment 2654112.0 -882000.0 -0.74 2484148.0 -912000.0 -0.73 -1.0402 -0.9999 3634144 CBKinase1_024336 Ic1ccc(NC(=O)CSc2ncccn2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E17 mock treatment 2952704.0 -583000.0 -0.49 2642282.0 -754000.0 -0.6 -0.773 -0.9951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E18 mock treatment 2774570.0 -762000.0 -0.64 2801118.0 -595000.0 -0.47 -0.7897 -0.9889 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E19 compound treatment 3098935.0 -437000.0 -0.37 2822013.0 -574000.0 -0.46 -0.5845 -0.9942 3634145 CBKinase1_024337 COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E20 compound treatment 3224952.0 -311000.0 -0.26 2427285.0 -969000.0 -0.77 -0.7318 -0.897 3634146 CBKinase1_024338 O=C(CSc1nnc[nH]1)NC2CC3CCC2C3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E21 compound treatment 3151995.0 -384000.0 -0.32 2595792.0 -801000.0 -0.64 -0.6804 -0.9506 3634147 CBKinase1_024339 Cc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)Cl)c4cccs4)n(n1)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E22 compound treatment 3057519.0 -479000.0 -0.4 3219343.0 -177000.0 -0.14 -0.3853 -0.9009 3634148 CBKinase1_024340 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3ccc(I)cc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E23 compound treatment 2779931.0 -756000.0 -0.64 2425465.0 -971000.0 -0.77 -0.9983 -0.9954 3634149 CBKinase1_024341 Cc1ccc(cc1)c2nc(c(SCC(=O)N)o2)S(=O)(=O)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 E24 compound treatment 2291040.0 -1250000.0 -1.05 2370844.0 -1030000.0 -0.82 -1.3206 -0.9923 3634150 CBKinase1_024342 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F01 mock treatment 1409249.0 -2130000.0 -1.79 1149777.0 -2250000.0 -1.79 -2.5348 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F02 mock treatment 1913426.0 -1620000.0 -1.37 2147500.0 -1250000.0 -1.0 -1.6717 -0.9878 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F03 compound treatment 1620314.0 -1920000.0 -1.62 3042792.0 -354000.0 -0.28 -1.342 -0.8181 3634151 CBKinase1_024343 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)C)c3ccccc23)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F04 compound treatment 2321264.0 -1210000.0 -1.02 1501537.0 -1890000.0 -1.51 -1.7926 -0.9821 3634152 CBKinase1_024344 O=S(=O)(N1CCOCC1)N2CCCN(CC2)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F05 compound treatment 1741115.0 -1800000.0 -1.51 4398885.0 1000000.0 0.8 -0.5056 -0.2954 3634153 CBKinase1_024345 COC(=O)c1ccccc1NC(=O)c2cccc(NC(=O)CSc3ccccc3)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F06 compound treatment 4432033.0 896000.0 0.76 2440934.0 -956000.0 -0.76 -0.0042 -0.0039 3634154 CBKinase1_024346 Cn1c(SCCC(=O)O)nnc1c2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F07 compound treatment 1921505.0 -1610000.0 -1.36 1650062.0 -1750000.0 -1.39 -1.9473 -0.9999 3634155 CBKinase1_024347 CCn1c(SCC(=O)Nc2ccc(I)cc2)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F08 compound treatment 2096644.0 -1440000.0 -1.21 1967065.0 -1430000.0 -1.14 -1.6642 -0.9995 3634156 CBKinase1_024348 CC(C)NC(=O)Cn1ccc(n1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F09 mock treatment 2404062.0 -1130000.0 -0.95 2112328.0 -1280000.0 -1.02 -1.3989 -0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F10 mock treatment 2724027.0 -812000.0 -0.69 2104189.0 -1290000.0 -1.03 -1.2127 -0.9804 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F11 compound treatment 2607136.0 -929000.0 -0.78 2093789.0 -1300000.0 -1.04 -1.2883 -0.9904 3634157 CBKinase1_024349 COc1ccc(cc1NC(=O)COc2cc(C)ccc2C(C)C)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F12 compound treatment 2645010.0 -891000.0 -0.75 2486532.0 -910000.0 -0.73 -1.0443 -0.9998 3634158 CBKinase1_024350 Cn1c(Cc2csc(N)n2)nnc1SC/C=C/c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F13 compound treatment 2512209.0 -1020000.0 -0.86 2325075.0 -1070000.0 -0.85 -1.2145 -1.0 3634160 CBKinase1_024351 CC(C(=O)Nc1sc2CCCc2c1C#N)n3cc(cn3)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F14 compound treatment 2436285.0 -1100000.0 -0.93 2464956.0 -931000.0 -0.74 -1.181 -0.9939 3634161 CBKinase1_024352 Fc1ccc(c2nc3cc(NC(=O)COc4ccccc4Cl)ccc3o2)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F15 compound treatment 3028775.0 -507000.0 -0.43 2653018.0 -743000.0 -0.59 -0.7216 -0.9872 3634162 CBKinase1_024353 COc1ccc(C)cc1Nc2nc(N)nc(n2)c3oc4ccccc4c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F16 compound treatment 2871263.0 -665000.0 -0.56 2590726.0 -806000.0 -0.64 -0.8506 -0.9977 3634163 CBKinase1_024354 Fc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F17 mock treatment 2702305.0 -834000.0 -0.7 2551377.0 -845000.0 -0.67 -0.9736 -0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F18 mock treatment 2735078.0 -801000.0 -0.68 2663754.0 -733000.0 -0.58 -0.8907 -0.9974 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F19 compound treatment 2388290.0 -1150000.0 -0.97 3365168.0 -31300.0 -0.02 -0.7022 -0.7251 3634164 CBKinase1_024355 OC1(CC(=O)c2ccccn2)C(=O)N(Cc3ccc(Cl)cc3)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F20 compound treatment 2554083.0 -982000.0 -0.83 2436285.0 -960000.0 -0.77 -1.1269 -0.9992 3634165 CBKinase1_024356 CC1(C)Cc2c(CS1)c(nc3sc4c(NCCN5CCOCC5)ncnc4c23)N6CCOCC6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F21 compound treatment 3644658.0 109000.0 0.09 2508664.0 -888000.0 -0.71 -0.4356 -0.6105 3634166 CBKinase1_024357 COc1cc(ccc1Br)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F22 compound treatment 2397112.0 -1140000.0 -0.96 2109561.0 -1290000.0 -1.03 -1.4046 -0.9995 3634167 CBKinase1_024358 CC(C(=O)Nc1cc(ccc1Cl)C(F)(F)F)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F23 compound treatment 2596778.0 -939000.0 -0.79 2853862.0 -543000.0 -0.43 -0.8661 -0.9594 3634168 CBKinase1_024359 CC(=O)c1ccc(NC(=O)CSc2nc(O)cc(n2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 F24 compound treatment 2063611.0 -1470000.0 -1.24 1792381.0 -1600000.0 -1.28 -1.7823 -0.9999 3634169 CBKinase1_024360 CC(=O)Nc1ccc(NC(=O)Cn2cc(cn2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G01 compound treatment 3063150.0 -473000.0 -0.4 3282058.0 -114000.0 -0.09 -0.3466 -0.8469 3634170 CBKinase1_024361 Cc1cc2nn(nc2cc1NC(=O)COc3ccc(Br)cc3)c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G02 compound treatment 3435988.0 -100000.0 -0.08 3052708.0 -344000.0 -0.27 -0.2535 -0.884 3634171 CBKinase1_024362 COC(=O)COc1ccc(NC(=O)c2ccc(NC(=O)C)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G03 mock treatment 3489384.0 -46700.0 -0.04 3382457.0 -14000.0 -0.01 -0.0358 -0.8728 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G04 mock treatment 4015881.0 480000.0 0.4 3612503.0 216000.0 0.17 0.4079 0.9275 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G05 compound treatment 3577897.0 41800.0 0.04 3240292.0 -156000.0 -0.12 -0.0631 -0.4878 3634172 CBKinase1_024363 CC(Oc1ccccc1C)C(=O)Nc2ccccc2C(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G06 compound treatment 3367957.0 -168000.0 -0.14 3138195.0 -258000.0 -0.21 -0.2458 -0.9835 3634173 CBKinase1_024364 Cc1cc(C)n2nc(SCC(=O)O)nc2n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G07 compound treatment 3166079.0 -370000.0 -0.31 3281721.0 -115000.0 -0.09 -0.2854 -0.8774 3634174 CBKinase1_024365 CN(CC(=O)Nc1nnc[nH]1)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G08 compound treatment 3188445.0 -348000.0 -0.29 3653803.0 257000.0 0.21 -0.0623 -0.1741 3634175 CBKinase1_024366 COc1ccc(NC(=O)COc2cc(C)c(Br)cc2C)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G09 compound treatment 3252086.0 -284000.0 -0.24 3150509.0 -246000.0 -0.2 -0.308 -0.995 3634176 CBKinase1_024367 NC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(Cl)cc2Cl)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G10 compound treatment 3458693.0 -77400.0 -0.07 3456959.0 60500.0 0.05 -0.0121 -0.1487 3634177 CBKinase1_024368 Cc1cc(nc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)n1)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G11 compound treatment 2719691.0 -816000.0 -0.69 2866297.0 -530000.0 -0.42 -0.7857 -0.9725 3634178 CBKinase1_024369 CCOc1ccc(cc1)C(Nc2cccnc2)c3cc(Cl)c4cccnc4c3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G12 compound treatment 3468908.0 -67200.0 -0.06 3052647.0 -344000.0 -0.27 -0.2339 -0.8357 3634179 CBKinase1_024370 Cc1ccc(O)c(NC(=O)CCN2C(=O)c3ccccc3C2=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G13 compound treatment 3340827.0 -195000.0 -0.16 3584968.0 189000.0 0.15 -0.0102 -0.0459 3634180 CBKinase1_024371 COc1ccc(cc1)C(=O)NCC(=O)Nc2cccc(c2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G14 compound treatment 3427656.0 -108000.0 -0.09 3516287.0 120000.0 0.1 0.0028 0.0215 3634181 CBKinase1_024372 OC(=O)COc1cccc(NC(=O)c2ccc(cc2)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G15 compound treatment 3227662.0 -308000.0 -0.26 3445947.0 49500.0 0.04 -0.1561 -0.5931 3634182 CBKinase1_024373 Cc1cc(OCC(=O)Nc2cccnc2)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G16 compound treatment 3620776.0 84700.0 0.07 3429046.0 32600.0 0.03 0.0689 0.9063 3634183 CBKinase1_024374 CCN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G17 compound treatment 3522892.0 -13200.0 -0.01 3343734.0 -52700.0 -0.04 -0.0376 -0.865 3634184 CBKinase1_024375 CN(Cc1nc(no1)c2ccccc2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G18 compound treatment 3321750.0 -214000.0 -0.18 3479432.0 83000.0 0.07 -0.0811 -0.4212 3634185 CBKinase1_024376 Cc1ccc(NC(=O)c2ccco2)c(NC(=O)CCN3C(=O)c4ccccc4C3=O)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G19 mock treatment 3796607.0 260000.0 0.22 3272642.0 -124000.0 -0.1 0.0856 0.3554 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G20 mock treatment 3773770.0 238000.0 0.2 2541280.0 -855000.0 -0.68 -0.3402 -0.4789 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G21 compound treatment 3792751.0 257000.0 0.22 3893431.0 497000.0 0.4 0.4332 0.9596 3634186 CBKinase1_024377 COc1ccc(NC(=O)c2ccccc2NC(=O)COc3ccc(Cl)cc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G22 compound treatment 3482699.0 -53400.0 -0.05 2742968.0 -653000.0 -0.52 -0.4002 -0.7654 3634187 CBKinase1_024378 CCn1c(SCc2nc(no2)c3cccs3)nnc1c4c[nH]c5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G23 compound treatment 2779726.0 -756000.0 -0.64 2579181.0 -817000.0 -0.65 -0.9118 -0.9999 3634188 CBKinase1_024379 Cc1ccc2nc(cc(C(=O)NCCCn3ccnc3)c2c1)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 G24 compound treatment 2928157.0 -608000.0 -0.51 3180537.0 -216000.0 -0.17 -0.4843 -0.8953 3634189 CBKinase1_024380 Cc1cc(OCC(=O)Nc2ccccc2C(=O)N)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H01 compound treatment 2676799.0 -859000.0 -0.72 2574595.0 -822000.0 -0.66 -0.9757 -0.9987 3634190 CBKinase1_024381 COc1ccccc1c2noc(CCC(=O)Nc3ccccc3Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H02 compound treatment 3210489.0 -326000.0 -0.27 2911354.0 -485000.0 -0.39 -0.4676 -0.986 3634191 CBKinase1_024382 Cc1ccc(Nc2nc(Oc3ccc(OCc4ccccc4)nn3)nc(n2)N5CCOCC5)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H03 mock treatment 3379947.0 -156000.0 -0.13 2843062.0 -553000.0 -0.44 -0.405 -0.8799 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H04 mock treatment 3458651.0 -77500.0 -0.07 4093677.0 697000.0 0.56 0.3467 0.6197 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H05 compound treatment 3159526.0 -377000.0 -0.32 3104460.0 -292000.0 -0.23 -0.3892 -0.9883 3634192 CBKinase1_024383 CCOc1ccccc1c2nnc(SCC(=O)Nc3ccc(I)cc3)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H06 compound treatment 3875580.0 339000.0 0.29 3366693.0 -29700.0 -0.02 0.1857 0.6463 3634193 CBKinase1_024384 Cc1ccc(NC(=O)CSc2nnc(s2)c3cccnc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H07 compound treatment 3619522.0 83400.0 0.07 3440753.0 44300.0 0.04 0.0747 0.9492 3634194 CBKinase1_024385 COc1ccc(NC(=O)CNC(=O)c2ccco2)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H08 compound treatment 3388788.0 -147000.0 -0.12 3561836.0 165000.0 0.13 0.0053 0.0295 3634195 CBKinase1_024386 Cc1nn(C)c(C)c1CNC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H09 compound treatment 3296498.0 -240000.0 -0.2 3788112.0 392000.0 0.31 0.0778 0.2092 3634196 CBKinase1_024387 OC(=O)COc1cccc(NC(=O)c2ccc(I)cc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H10 compound treatment 3715538.0 179000.0 0.15 3546597.0 150000.0 0.12 0.1916 0.9932 3634197 CBKinase1_024388 Cc1nnc(SCC(=O)Nc2ccc(cc2)C(=O)O)[nH]1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H11 compound treatment 3452518.0 -83600.0 -0.07 3375649.0 -20800.0 -0.02 -0.0616 -0.8501 3634198 CBKinase1_024389 COC(=O)C1=C(C)Nc2ncnn2C1c3cccc(OC)c3OCc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H12 compound treatment 3550964.0 14800.0 0.01 3707791.0 311000.0 0.25 0.1843 0.7418 3634199 CBKinase1_024390 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H13 compound treatment 3803129.0 267000.0 0.23 3984574.0 588000.0 0.47 0.4907 0.9436 3634200 CBKinase1_024391 CCN(CC(=O)O)S(=O)(=O)c1cc(Cl)ccc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H14 compound treatment 3429601.0 -107000.0 -0.09 3145462.0 -251000.0 -0.2 -0.205 -0.9348 3634201 CBKinase1_024392 COc1ccc(C)cc1NC(=O)CSc2nc(SC)ns2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H15 compound treatment 3261316.0 -275000.0 -0.23 3142229.0 -254000.0 -0.2 -0.3072 -0.9978 3634202 CBKinase1_024393 Cc1nnc(SCc2cc(=O)[nH]c(Nc3nc(C)c4ccc(C)cc4n3)n2)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H16 compound treatment 3883488.0 347000.0 0.29 3580237.0 184000.0 0.15 0.3108 0.9487 3634203 CBKinase1_024394 CCOc1ccc(Nc2ncnc3n(cnc23)c4ccc(OCC)cc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H17 compound treatment 3723574.0 187000.0 0.16 3807361.0 411000.0 0.33 0.3434 0.9442 3634204 CBKinase1_024395 CC(C(=O)Nc1ccc(Br)c(C)c1)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H18 compound treatment 3137702.0 -398000.0 -0.34 2871630.0 -525000.0 -0.42 -0.5334 -0.9941 3634205 CBKinase1_024396 Cc1c(Br)c(nn1CC(=O)Nc2cccnc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H19 mock treatment 3299805.0 -236000.0 -0.2 2181468.0 -1210000.0 -0.97 -0.8257 -0.8352 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H20 mock treatment 4335877.0 800000.0 0.67 4162125.0 766000.0 0.61 0.9085 0.9987 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H21 compound treatment 4356421.0 820000.0 0.69 3093282.0 -303000.0 -0.24 0.3184 0.4344 3634206 CBKinase1_024397 O=C1N(CCCSc2nnnn2c3ccccc3)C(=O)c4cccc5cccc1c45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H22 compound treatment 3852618.0 316000.0 0.27 3790993.0 395000.0 0.31 0.4111 0.9967 3634207 CBKinase1_024398 COC(=O)c1ccccc1NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H23 compound treatment 3534959.0 -1170.0 0.0 3216115.0 -180000.0 -0.14 -0.1023 -0.7119 3634208 CBKinase1_024399 Cc1cc(nn1CC(=O)Nc2ccc(C)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 H24 compound treatment 3437858.0 -98300.0 -0.08 3227470.0 -169000.0 -0.13 -0.1538 -0.9728 3634209 CBKinase1_024400 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)NCCN3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I01 compound treatment 2621371.0 -915000.0 -0.77 2706362.0 -690000.0 -0.55 -0.9345 -0.9862 3634210 CBKinase1_024401 COc1ccccc1NC(=O)CNC(=O)c2ccc(C)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I02 compound treatment 3163308.0 -373000.0 -0.31 3122461.0 -274000.0 -0.22 -0.3768 -0.9841 3634211 CBKinase1_024402 NC(=O)CSCC(=O)Nc1ccc(Br)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I03 compound treatment 3175874.0 -360000.0 -0.3 3131216.0 -265000.0 -0.21 -0.3643 -0.9843 3634212 CBKinase1_024403 COc1ccc(OC)c(NC(=O)CNC(=O)c2ccc(OC)c(OC)c2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I04 compound treatment 3459294.0 -76800.0 -0.06 3511151.0 115000.0 0.09 0.0188 0.168 3634213 CBKinase1_024404 CCOc1ccccc1OCc2nn3c(nnc3s2)c4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I05 mock treatment 3423583.0 -113000.0 -0.09 3553581.0 157000.0 0.13 0.0214 0.1364 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I06 mock treatment 3373672.0 -162000.0 -0.14 3701611.0 305000.0 0.24 0.0751 0.269 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I07 compound treatment 3536312.0 186.0 0.0 3576011.0 180000.0 0.14 0.1013 0.7079 3634214 CBKinase1_024405 COC(=O)c1ccccc1NC(=O)c2cccc(NC(=O)COc3cc(C)c(Cl)c(C)c3)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I08 compound treatment 3337146.0 -199000.0 -0.17 3560179.0 164000.0 0.13 -0.0264 -0.1242 3634215 CBKinase1_024406 OC1(CC(=O)c2ccncc2)C(=O)N(Cc3ccc(Cl)cc3)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I09 compound treatment 3345559.0 -191000.0 -0.16 3417033.0 20600.0 0.02 -0.1021 -0.6316 3634216 CBKinase1_024407 Cc1nc(SCC(=O)Nc2ccc(I)cc2)nc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I10 compound treatment 3427074.0 -109000.0 -0.09 3271595.0 -125000.0 -0.1 -0.1354 -0.9992 3634217 CBKinase1_024408 Clc1ccc(cc1)c2nnc(SCC(=O)NC3CC4CCC3C4)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I11 compound treatment 3284697.0 -251000.0 -0.21 3265832.0 -131000.0 -0.1 -0.2236 -0.9463 3634218 CBKinase1_024409 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C(C)Oc2ccccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I12 compound treatment 3545930.0 9800.0 0.01 3886278.0 490000.0 0.39 0.2819 0.7219 3634219 CBKinase1_024410 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2cc(C)c(Br)cc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I13 compound treatment 3577913.0 41800.0 0.04 3464387.0 67900.0 0.05 0.0632 0.9784 3634220 CBKinase1_024411 COc1ccc(cc1OC)c2noc(CSc3nnc(c4ccco4)n3c5ccccc5)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I14 compound treatment 3560708.0 24600.0 0.02 3893207.0 497000.0 0.4 0.2946 0.7431 3634221 CBKinase1_024412 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccccc4)c5ccc(Br)cc51 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I15 compound treatment 3602345.0 66200.0 0.06 4138423.0 742000.0 0.59 0.4577 0.7705 3634222 CBKinase1_024413 Cc1c(Cl)c(C)c(Cl)c(OCC(=O)Nc2ccccc2N3CCOCC3)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I16 compound treatment 4058967.0 523000.0 0.44 3672210.0 276000.0 0.22 0.4673 0.9483 3634223 CBKinase1_024414 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccccc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I17 compound treatment 3500413.0 -35700.0 -0.03 4053083.0 657000.0 0.52 0.3488 0.6653 3634224 CBKinase1_024415 CC(C)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I18 compound treatment 4063584.0 527000.0 0.44 4431604.0 1040000.0 0.83 0.898 0.958 3634225 CBKinase1_024416 COc1ccc(NC(=O)CNC(=O)c2ccccc2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I19 compound treatment 3821273.0 285000.0 0.24 3479155.0 82700.0 0.07 0.2167 0.8689 3634226 CBKinase1_024417 Oc1c(ccc2cccnc12)C(Nc3cccnc3)c4ccccc4F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I20 compound treatment 4321860.0 786000.0 0.66 3180821.0 -216000.0 -0.17 0.3471 0.507 3122816 CBKinase1_024418 CCn1c(SCC(=O)N2CCCc3ccccc23)nnc1c4c[nH]c5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I21 mock treatment 4152393.0 616000.0 0.52 3023550.0 -373000.0 -0.3 0.1574 0.2629 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I22 mock treatment 3978099.0 442000.0 0.37 3050603.0 -346000.0 -0.28 0.0687 0.1482 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I23 compound treatment 2693200.0 -843000.0 -0.71 2521801.0 -875000.0 -0.7 -0.9957 -1.0 3634227 CBKinase1_024419 CN1CCN(CC(=O)Nc2sc3CC(CCc3c2C#N)C(C)(C)C)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 I24 compound treatment 3349389.0 -187000.0 -0.16 3706740.0 310000.0 0.25 0.0635 0.2166 3634228 CBKinase1_024420 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J01 compound treatment 3096235.0 -440000.0 -0.37 2918580.0 -478000.0 -0.38 -0.5317 -0.9999 3634229 CBKinase1_024421 CCn1c(SCC(=O)Nc2c(F)cc(F)cc2Br)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J02 compound treatment 3415913.0 -120000.0 -0.1 3434511.0 38100.0 0.03 -0.0502 -0.4747 3634230 CBKinase1_024422 Cc1c(Br)c(nn1CC(=O)Nc2cccc(c2)C(F)(F)F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J03 compound treatment 3878007.0 342000.0 0.29 3218593.0 -178000.0 -0.14 0.1037 0.3226 3634231 CBKinase1_024423 COCCNC(=O)c1ccccc1NC(=O)Nc2ccc(Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J04 compound treatment 3463217.0 -72900.0 -0.06 3577471.0 181000.0 0.14 0.0585 0.3732 3634232 CBKinase1_024424 CCOC(=O)N1CCN(Cc2nc(N)nc(Nc3ccc(Oc4ccccc4)cc3)n2)CC1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J05 mock treatment 3573935.0 37800.0 0.03 3770596.0 374000.0 0.3 0.2334 0.7783 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J06 mock treatment 3629528.0 93400.0 0.08 3686667.0 290000.0 0.23 0.2193 0.8973 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J07 compound treatment 3726975.0 191000.0 0.16 3486709.0 90300.0 0.07 0.1647 0.9341 3634233 CBKinase1_024425 COc1cc2c(cc1NC(=O)C(C)Oc3ccccc3C)oc4ccccc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J08 compound treatment 3857143.0 321000.0 0.27 3799179.0 403000.0 0.32 0.4184 0.9964 3634234 CBKinase1_024426 COC(=O)CCC(=O)NC(=S)Nc1c(C)cccc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J09 compound treatment 4317927.0 782000.0 0.66 4011100.0 615000.0 0.49 0.8127 0.9893 3634235 CBKinase1_024427 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cccc(c2)c3nn4c(C)nnc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J10 compound treatment 3768324.0 232000.0 0.2 3974523.0 578000.0 0.46 0.4643 0.9274 3634236 CBKinase1_024428 CC(C)c1cccc(C)c1NC(=O)CN(C2CCCCC2)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J11 compound treatment 3864258.0 328000.0 0.28 4113690.0 717000.0 0.57 0.5999 0.9446 3634237 CBKinase1_024429 CCN(CC(=O)Nc1ccc(cc1)C(=O)N)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J12 compound treatment 4015079.0 479000.0 0.4 3719072.0 323000.0 0.26 0.4675 0.9762 3634238 CBKinase1_024430 Cc1ccccc1NS(=O)(=O)c2ccc(NC(=O)c3nc4ncccn4n3)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J13 compound treatment 3748748.0 213000.0 0.18 3934432.0 538000.0 0.43 0.43 0.9252 3634239 CBKinase1_024431 CCOc1c(Cl)cc(CNCc2ccccn2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J14 compound treatment 4188518.0 652000.0 0.55 4127961.0 732000.0 0.58 0.8014 0.9996 1500362 CBKinase1_024432 CN(C)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3c(F)cccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J15 compound treatment 2576994.0 -959000.0 -0.81 2695151.0 -701000.0 -0.56 -0.9673 -0.9837 3634240 CBKinase1_024433 Cc1ccccc1CN2C(=O)C(O)(CC(=O)c3cccc(c3)[N+](=O)[O-])c4cc(Cl)ccc24 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J16 compound treatment 4000646.0 465000.0 0.39 4367447.0 971000.0 0.77 0.8243 0.9503 3634241 CBKinase1_024434 Cc1nn(C(=O)Cn2cc(cn2)[N+](=O)[O-])c(C)c1I 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J17 compound treatment 4332129.0 796000.0 0.67 4518741.0 1120000.0 0.89 1.1073 0.99 3634242 CBKinase1_024435 CCOc1ccc(NC(=O)Cn2nc(cc2C)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J18 compound treatment 4003829.0 468000.0 0.39 4364603.0 968000.0 0.77 0.8246 0.9515 3634243 CBKinase1_024436 Cc1ccc(OCC(=O)Nc2cccc3ncccc23)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J19 compound treatment 4687960.0 1150000.0 0.97 4034400.0 638000.0 0.51 1.0466 0.9544 3634244 CBKinase1_024437 COc1ccccc1NC(=O)CSc2nc(C)cc(n2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J20 compound treatment 4256810.0 721000.0 0.61 4688409.0 1290000.0 1.03 1.158 0.9684 3634245 CBKinase1_024438 COc1ccc(cc1)n2c(SCCC(=O)O)nnc2c3ccncc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J21 mock treatment 4035092.0 499000.0 0.42 4917014.0 1520000.0 1.21 1.1546 0.8999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J22 mock treatment 4235051.0 699000.0 0.59 5265626.0 1870000.0 1.49 1.4703 0.9177 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J23 compound treatment 4065515.0 529000.0 0.45 4228317.0 832000.0 0.66 0.7846 0.9815 3634246 CBKinase1_024439 CC(C(=O)Nc1c(C)n(C)n(c2ccccc2)c1=O)n3nc([N+](=O)[O-])c(Br)c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 J24 compound treatment 3390266.0 -146000.0 -0.12 3614311.0 218000.0 0.17 0.0358 0.1682 3634247 CBKinase1_024440 CN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(Cl)ccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K01 compound treatment 1408302.0 -2130000.0 -1.79 1848699.0 -1550000.0 -1.23 -2.1414 -0.9833 1321493 CBKinase1_024441 O=C(CN1C(=O)c2ccccc2C1=O)Nc3cccc(c3)c4nc5ccccc5[nH]4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K02 compound treatment 2059708.0 -1480000.0 -1.25 2208035.0 -1190000.0 -0.95 -1.5504 -0.9909 3634248 CBKinase1_024442 CCn1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1c4ccc(Cl)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K03 compound treatment 2608082.0 -928000.0 -0.78 3911209.0 515000.0 0.41 -0.2634 -0.298 3634249 CBKinase1_024443 COc1ccc(NC(=O)C(=O)NCC(=O)Nc2ccc(OC)c(Cl)c2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K04 compound treatment 2212412.0 -1320000.0 -1.12 2237209.0 -1160000.0 -0.92 -1.4429 -0.9956 3634250 CBKinase1_024444 Cc1cccc(c1)n2nc([N+](=O)[O-])c(NCc3cccnc3)[n+]2[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K05 compound treatment 3247873.0 -288000.0 -0.24 2984782.0 -412000.0 -0.33 -0.4039 -0.9891 3634251 CBKinase1_024445 CSc1ccc(cc1)C(Nc2cccnc2)c3ccc4cccnc4c3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K06 compound treatment 3603729.0 67600.0 0.06 3376059.0 -20400.0 -0.02 0.0288 0.4863 3634252 CBKinase1_024446 Cc1cc2c(=O)n(C)c(SCC(=O)c3cc4ccccc4o3)nc2s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K07 mock treatment 3195354.0 -341000.0 -0.29 3396633.0 191.0 0.0 -0.2031 -0.7067 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K08 mock treatment 3661229.0 125000.0 0.11 3340567.0 -55900.0 -0.04 0.0431 0.3765 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K09 compound treatment 3188068.0 -348000.0 -0.29 3635923.0 239000.0 0.19 -0.0726 -0.2074 3634253 CBKinase1_024447 [O-][N+](=O)c1ccc(cc1)C(=O)NCC(=O)Nc2ccccc2C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K10 compound treatment 3215753.0 -320000.0 -0.27 3156748.0 -240000.0 -0.19 -0.3262 -0.9856 3634254 CBKinase1_024448 Cc1ccc(s1)C(=O)CC2(O)C(=O)N(CC(=O)N)c3ccccc32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K11 compound treatment 3417579.0 -119000.0 -0.1 3434838.0 38400.0 0.03 -0.0491 -0.4692 3634255 CBKinase1_024449 Cc1cc(OCC(=O)Nc2ccccc2C(=O)N3CCCCC3)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K12 compound treatment 3149380.0 -387000.0 -0.33 3088091.0 -308000.0 -0.25 -0.4045 -0.9903 3634256 CBKinase1_024450 Ic1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K13 compound treatment 2974013.0 -562000.0 -0.47 2586415.0 -810000.0 -0.65 -0.7918 -0.9885 3634257 CBKinase1_024451 Cc1ccc(C)c(c1)C(Nc2cccnc2)c3cc(Cl)c4cccnc4c3O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K14 compound treatment 3385261.0 -151000.0 -0.13 3086939.0 -310000.0 -0.25 -0.2644 -0.9526 3634258 CBKinase1_024452 CN(CC(=O)Nc1ccccc1C(=O)N)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K15 mock treatment 3944998.0 409000.0 0.34 3413962.0 17500.0 0.01 0.2537 0.7351 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K16 mock treatment 3459008.0 -77100.0 -0.07 3278345.0 -118000.0 -0.09 -0.1126 -0.9837 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K17 compound treatment 3058531.0 -478000.0 -0.4 3865007.0 469000.0 0.37 -0.0208 -0.0378 3634259 CBKinase1_024453 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K18 compound treatment 2903245.0 -633000.0 -0.53 2232328.0 -1160000.0 -0.93 -1.0336 -0.9655 3634260 CBKinase1_024454 CC(O)CNCCCOc1c(C)cc(Cl)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K19 compound treatment 2941360.0 -595000.0 -0.5 3477834.0 81400.0 0.06 -0.3089 -0.6106 3634261 CBKinase1_024455 COc1ccc(cc1OC)c2noc(CSc3nnc(c4cccs4)n3c5ccccc5)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K20 compound treatment 2930349.0 -606000.0 -0.51 3220269.0 -176000.0 -0.14 -0.4606 -0.8692 3634262 CBKinase1_024456 COc1cc(Cl)c(C)cc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K21 compound treatment 3628646.0 92500.0 0.08 3230796.0 -166000.0 -0.13 -0.0382 -0.2489 3634263 CBKinase1_024457 CC(=O)c1ccc(NC(=O)CSc2nc(c(C#N)c(=O)[nH]2)c3ccccc3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K22 compound treatment 2885107.0 -651000.0 -0.55 2820188.0 -576000.0 -0.46 -0.7131 -0.9961 3634264 CBKinase1_024458 CCn1c(SCC(=O)Nc2c(Cl)cc(Cl)cc2Cl)nnc1c3ccccc3F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K23 mock treatment 2661740.0 -874000.0 -0.74 2626833.0 -770000.0 -0.61 -0.9553 -0.9958 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 K24 mock treatment 2322884.0 -1210000.0 -1.02 2527920.0 -869000.0 -0.69 -1.2131 -0.9819 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L01 compound treatment 2413668.0 -1120000.0 -0.95 2123278.0 -1270000.0 -1.01 -1.387 -0.9994 3634265 CBKinase1_024459 COc1cc(NC(=O)COc2c(Cl)c(C)c(Cl)c(C)c2Cl)c(OC)cc1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L02 compound treatment 2698933.0 -837000.0 -0.71 2819654.0 -577000.0 -0.46 -0.8244 -0.9784 3634266 CBKinase1_024460 Fc1ccc(cc1)C(=O)N2CCNC(=O)C2CC(=O)OCc3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L03 compound treatment 2779534.0 -757000.0 -0.64 3683774.0 287000.0 0.23 -0.2893 -0.4267 3634267 CBKinase1_024461 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nnc[nH]2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L04 compound treatment 3928499.0 392000.0 0.33 3909659.0 513000.0 0.41 0.5233 0.9945 3634268 CBKinase1_024462 Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)n3c(S)nnc3c4ccc5ccccc5n4)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L05 compound treatment 3841226.0 305000.0 0.26 4110750.0 714000.0 0.57 0.5846 0.9356 3634269 CBKinase1_024463 CN(C)S(=O)(=O)N(CC(=O)Nc1ccccc1C(F)(F)F)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L06 compound treatment 4103291.0 567000.0 0.48 4408920.0 1010000.0 0.81 0.9089 0.9688 3634270 CBKinase1_024464 CCOC(=O)c1c(C)oc2ccc(cc12)S(=O)(=O)n3cc(c(N)n3)c4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L07 mock treatment 3837121.0 301000.0 0.25 3980578.0 584000.0 0.47 0.5087 0.9593 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L08 mock treatment 4031749.0 496000.0 0.42 3788009.0 392000.0 0.31 0.5163 0.9896 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L09 compound treatment 4523198.0 987000.0 0.83 3461298.0 64900.0 0.05 0.6253 0.7496 3634271 CBKinase1_024465 COC(=O)C1=C(C)Nc2nnnn2C1c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L10 compound treatment 3920704.0 385000.0 0.32 3857228.0 461000.0 0.37 0.4891 0.9981 3634272 CBKinase1_024466 COc1cc(C)c(Br)cc1S(=O)(=O)NCc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L11 compound treatment 3349635.0 -186000.0 -0.16 3640419.0 244000.0 0.19 0.0263 0.105 3634273 CBKinase1_024467 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(cc2)N3CCN(CC3)C(=O)c4ccco4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L12 compound treatment 3379202.0 -157000.0 -0.13 3550567.0 154000.0 0.12 -0.0067 -0.0373 3634274 CBKinase1_024468 Cc1onc(c1C(=O)NCc2nc(no2)c3ccccc3)c4ccccc4Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L13 compound treatment 3617285.0 81200.0 0.07 3633504.0 237000.0 0.19 0.182 0.9057 1984845 CBKinase1_024469 CCOC(=O)c1nnn(c1CN2CCOCC2)c3nonc3n4cccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L14 compound treatment 3791663.0 256000.0 0.22 3777116.0 381000.0 0.3 0.367 0.986 3634275 CBKinase1_024470 Cc1ccc(Nc2nc(N)nc(CN3CCN(CC3)C(c4ccccc4)c5ccccc5)n2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L15 mock treatment 3527292.0 -8830.0 -0.01 3358664.0 -37800.0 -0.03 -0.0266 -0.8563 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L16 mock treatment 3349311.0 -187000.0 -0.16 3007110.0 -389000.0 -0.31 -0.3308 -0.9506 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L17 compound treatment 3198776.0 -337000.0 -0.28 2969822.0 -427000.0 -0.34 -0.4417 -0.9961 3634276 CBKinase1_024471 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L18 compound treatment 3074210.0 -462000.0 -0.39 3050108.0 -346000.0 -0.28 -0.4707 -0.9858 3634277 CBKinase1_024472 Cc1nn(CC(=O)NCc2ccccn2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L19 compound treatment 3520077.0 -16000.0 -0.01 3891075.0 495000.0 0.39 0.2692 0.6824 3634278 CBKinase1_024473 CC(=O)c1cc(C)ccc1OC(=O)CCN2C(=O)c3ccccc3C2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L20 compound treatment 3012995.0 -523000.0 -0.44 3126377.0 -270000.0 -0.22 -0.4642 -0.9455 3634279 CBKinase1_024474 Cc1ccc(CN2C(=O)C(O)(CC(=O)c3cccc(N)c3)c4cc(Cl)ccc24)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L21 compound treatment 3366087.0 -170000.0 -0.14 2870172.0 -526000.0 -0.42 -0.398 -0.8979 3634280 CBKinase1_024475 CN(C)c1nc(OCCNC(=O)Nc2ccc(Cl)cc2)nc(n1)N(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L22 compound treatment 4414670.0 879000.0 0.74 3049923.0 -347000.0 -0.28 0.3287 0.4156 3634281 CBKinase1_024476 Cn1c(=O)n(C)c2nc(NCCN3CCOCC3)n(Cc4cccc(F)c4)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L23 mock treatment 2667631.0 -868000.0 -0.73 3082212.0 -314000.0 -0.25 -0.6951 -0.8978 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 L24 mock treatment 2661810.0 -874000.0 -0.74 2727767.0 -669000.0 -0.53 -0.8983 -0.9873 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M01 compound treatment 3281812.0 -254000.0 -0.21 2670369.0 -726000.0 -0.58 -0.5609 -0.9088 3634282 CBKinase1_024477 Cc1ccc(cc1)c2ccc(CCC(=O)O)n2CC3CCCO3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M02 compound treatment 2237584.0 -1300000.0 -1.1 2212283.0 -1180000.0 -0.94 -1.4419 -0.9973 3634283 CBKinase1_024478 COc1ccc(C)cc1S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccccc3C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M03 compound treatment 3310488.0 -226000.0 -0.19 3476671.0 80200.0 0.06 -0.0894 -0.4451 3634284 CBKinase1_024479 CC(Oc1ccccc1)C(=O)Nc2ncccc2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M04 compound treatment 4076916.0 541000.0 0.46 4145208.0 749000.0 0.6 0.7446 0.9912 3634285 CBKinase1_024480 Oc1cc(OCC(=O)c2ccc(Cl)cc2)cc3oc4ccccc4c(=O)c13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M05 compound treatment 3754205.0 218000.0 0.18 3675097.0 279000.0 0.22 0.2871 0.9956 3634286 CBKinase1_024481 Cc1cc(OCC(=O)Nc2nnc[nH]2)c(C)cc1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M06 compound treatment 4381789.0 846000.0 0.71 3365306.0 -31100.0 -0.02 0.4868 0.6821 1189235 CBKinase1_024482 NC(=O)CSc1nnc(Cc2ccccc2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M07 compound treatment 3702675.0 167000.0 0.14 3613294.0 217000.0 0.17 0.2216 0.9947 3634287 CBKinase1_024483 CCC(=O)c1cn(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M08 compound treatment 3917076.0 381000.0 0.32 3762419.0 366000.0 0.29 0.4335 0.9988 3634288 CBKinase1_024484 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2cc(Cl)c(Cl)cc2Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M09 mock treatment 4034232.0 498000.0 0.42 3554958.0 159000.0 0.13 0.3864 0.8808 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M10 mock treatment 4312798.0 777000.0 0.66 3738208.0 342000.0 0.27 0.6559 0.9244 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M11 compound treatment 4205382.0 669000.0 0.56 4093749.0 697000.0 0.56 0.7922 1.0 3634289 CBKinase1_024485 CN(CC(=O)Nc1ccc(Cl)cc1C(F)(F)F)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M12 compound treatment 3592470.0 56300.0 0.05 3489707.0 93300.0 0.07 0.0862 0.9766 3634290 CBKinase1_024486 COc1ccc(cc1NC(=O)C(C)Oc2ccccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M13 mock treatment 4344089.0 808000.0 0.68 3652255.0 256000.0 0.2 0.6261 0.8801 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M14 mock treatment 4395368.0 859000.0 0.72 4261350.0 865000.0 0.69 0.9999 0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M15 compound treatment 4128693.0 593000.0 0.5 3681370.0 285000.0 0.23 0.514 0.9363 3634291 CBKinase1_024487 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccc(F)cc2F)S(=O)(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M16 compound treatment 4042691.0 507000.0 0.43 4176635.0 780000.0 0.62 0.7419 0.9832 3634292 CBKinase1_024488 FC(F)(F)c1ccccc1NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M17 compound treatment 4060249.0 524000.0 0.44 4234387.0 838000.0 0.67 0.7849 0.9799 3634293 CBKinase1_024489 CN(CC(=O)Nc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M18 compound treatment 4499108.0 963000.0 0.81 4540641.0 1140000.0 0.91 1.2192 0.9983 3634294 CBKinase1_024490 Cn1c(SCc2nc(no2)c3cccs3)nnc1c4ccco4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M19 compound treatment 3608359.0 72200.0 0.06 3737704.0 341000.0 0.27 0.2354 0.8446 3634295 CBKinase1_024491 CC(=O)c1c(C)n(CC(=O)O)c2ccccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M20 compound treatment 3984225.0 448000.0 0.38 3285857.0 -111000.0 -0.09 0.2049 0.528 3634296 CBKinase1_024492 COc1cc(NC(=O)COc2ccc(cc2)C(C)C)ccc1c3cc4ccccc4oc3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M21 compound treatment 4213517.0 677000.0 0.57 3043732.0 -353000.0 -0.28 0.2052 0.3223 3634297 CBKinase1_024493 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccccc2SC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M22 compound treatment 4370008.0 834000.0 0.7 3578746.0 182000.0 0.15 0.6001 0.8355 3634298 CBKinase1_024494 COc1ccc(NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M23 compound treatment 3366493.0 -170000.0 -0.14 4084215.0 688000.0 0.55 0.2864 0.5056 3634299 CBKinase1_024495 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)NC2CC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 M24 compound treatment 2807502.0 -729000.0 -0.61 3692556.0 296000.0 0.24 -0.2677 -0.4066 3634300 CBKinase1_024496 O=C1N(CCCc2nc3c4c5CCCCCc5sc4ncn3n2)C(=O)c6ccccc16 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N01 compound treatment 2802560.0 -734000.0 -0.62 2784720.0 -612000.0 -0.49 -0.7823 -0.993 3634301 CBKinase1_024497 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N02 compound treatment 3496118.0 -40000.0 -0.03 2971214.0 -425000.0 -0.34 -0.2635 -0.7737 3634302 CBKinase1_024498 FC(F)(F)c1cnc(NC(=O)C2COc3ccccc3O2)c(Cl)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N03 compound treatment 3679704.0 144000.0 0.12 2963907.0 -433000.0 -0.34 -0.1581 -0.4328 3634303 CBKinase1_024499 COc1cccc(NC(=O)CNC(=O)c2ccccc2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N04 compound treatment 3730804.0 195000.0 0.16 3658340.0 262000.0 0.21 0.2637 0.9929 3634304 CBKinase1_024500 CCOC(=O)c1cnc(SCC(=O)Nc2ccc(F)c(F)c2F)nc1N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N05 compound treatment 3371949.0 -164000.0 -0.14 3503273.0 107000.0 0.09 -0.0377 -0.232 3634305 CBKinase1_024501 COc1ccc(cc1OC)c2noc(CSc3nc4ccccc4c(=O)n3c5ccccc5)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N06 compound treatment 3732322.0 196000.0 0.17 3218804.0 -178000.0 -0.14 0.0169 0.0776 3634306 CBKinase1_024502 Cc1ccc(OCC(=O)Nc2ccccc2c3nc4ccccc4s3)cc1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N07 compound treatment 3881585.0 345000.0 0.29 4112052.0 716000.0 0.57 0.6094 0.9514 3634307 CBKinase1_024503 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2cc(ccc2Cl)c3nc4ncccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N08 compound treatment 3721409.0 185000.0 0.16 4402156.0 1010000.0 0.8 0.6773 0.8294 3634308 CBKinase1_024504 Cc1cc(I)ccc1NC(=O)Cn2ccc(n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N09 mock treatment 3700072.0 164000.0 0.14 4009777.0 613000.0 0.49 0.4435 0.8729 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N10 mock treatment 4121540.0 585000.0 0.49 3775985.0 380000.0 0.3 0.5631 0.9723 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N11 compound treatment 3746629.0 211000.0 0.18 3691140.0 295000.0 0.23 0.2916 0.9905 3634309 CBKinase1_024505 CN(CC(=O)Nc1ccncc1)S(=O)(=O)c2ccc(Br)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N12 compound treatment 3787750.0 252000.0 0.21 3853181.0 457000.0 0.36 0.4075 0.967 3634310 CBKinase1_024506 Cc1c(Br)c(nn1CC(=O)Nc2sc3CCCCc3c2C#N)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N13 mock treatment 4068257.0 532000.0 0.45 3818279.0 422000.0 0.34 0.5551 0.9899 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N14 mock treatment 4478785.0 943000.0 0.8 4248380.0 852000.0 0.68 1.0424 0.9969 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N15 compound treatment 4110648.0 575000.0 0.48 3917291.0 521000.0 0.42 0.6362 0.997 3634311 CBKinase1_024507 COc1ccc(Cl)c(Cn2c(NC3CCCCC3)nc4n(C)c(=O)n(C)c(=O)c24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N16 compound treatment 4582780.0 1050000.0 0.88 3913846.0 517000.0 0.41 0.9159 0.9399 3634312 CBKinase1_024508 COc1ccc(NC(=O)NCCN2CCN(CC2)c3cc(OC)ccc3OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N17 compound treatment 4055499.0 519000.0 0.44 4235587.0 839000.0 0.67 0.7827 0.979 3634313 CBKinase1_024509 CC(C(=O)Nc1cc(Cl)ccc1C)n2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N18 compound treatment 4525384.0 989000.0 0.83 4595544.0 1200000.0 0.96 1.2658 0.9977 3634314 CBKinase1_024510 CC(C(=O)NCc1cccnc1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N19 compound treatment 4355321.0 819000.0 0.69 5148656.0 1750000.0 1.4 1.4761 0.9473 3634315 CBKinase1_024511 CC(=O)c1cccc(NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N20 compound treatment 3613254.0 77100.0 0.07 3842243.0 446000.0 0.36 0.2973 0.8229 3634316 CBKinase1_024512 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccc(Cl)cc4)c5ccc(Cl)cc51 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N21 compound treatment 4771443.0 1240000.0 1.04 3974223.0 578000.0 0.46 1.0624 0.9326 3634317 CBKinase1_024513 CCCC1=C(C(c2ccco2)n3ncnc3N1)C(=O)OCC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N22 compound treatment 4636881.0 1100000.0 0.93 4352275.0 956000.0 0.76 1.1952 0.9952 3634318 CBKinase1_024514 COc1ccc(OCC(=O)Nc2cccc(Cl)c2N3CCOCC3)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N23 compound treatment 3747036.0 211000.0 0.18 4403788.0 1010000.0 0.8 0.6935 0.8433 1386375 CBKinase1_024515 Nc1ncnc2n(CCN3CCOCC3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 N24 compound treatment 3610622.0 74500.0 0.06 3784740.0 388000.0 0.31 0.2633 0.8337 3634319 CBKinase1_024516 CCOc1c(Cl)c(Cl)ccc1S(=O)(=O)NCc2ccccn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O01 compound treatment 3289454.0 -247000.0 -0.21 2884936.0 -512000.0 -0.41 -0.4354 -0.9513 3634320 CBKinase1_024517 COc1ccccc1NC(=O)CNC(=O)c2ccccc2F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O02 compound treatment 3477827.0 -58300.0 -0.05 3237190.0 -159000.0 -0.13 -0.1245 -0.9148 3212425 CBKinase1_024518 OC(=O)CC(C(=O)O)c1ccc(F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O03 compound treatment 5060249.0 1520000.0 1.29 3826702.0 430000.0 0.34 1.1515 0.8655 3634321 CBKinase1_024519 COc1ccc(cc1OC)c2noc(CSc3nc4sc(C)c(C)c4c(=O)n3c5ccccc5)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O04 compound treatment 4774512.0 1240000.0 1.04 3417377.0 20900.0 0.02 0.7504 0.7183 3634322 CBKinase1_024520 CN(C)S(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O05 compound treatment 3945364.0 409000.0 0.35 3783116.0 387000.0 0.31 0.462 0.9984 3634323 CBKinase1_024521 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccccc2C(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O06 compound treatment 3151863.0 -384000.0 -0.32 4197169.0 801000.0 0.64 0.2221 0.3103 3634324 CBKinase1_024522 Cc1cccc(NC(=O)COc2ccc(cc2Cl)S(=O)(=O)N3CCCCC3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O07 compound treatment 3862175.0 326000.0 0.28 3805993.0 410000.0 0.33 0.4253 0.9964 3634325 CBKinase1_024523 COc1ccc(NC(=O)C(C)Oc2ccccc2C)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O08 compound treatment 4544224.0 1010000.0 0.85 4669598.0 1270000.0 1.01 1.3188 0.9961 3634326 CBKinase1_024524 COc1ccc(cc1NC(=O)COc2ccc(Br)cc2)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O09 compound treatment 4359943.0 824000.0 0.69 4132204.0 736000.0 0.59 0.906 0.9964 3634327 CBKinase1_024525 CN(C)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O10 compound treatment 3610149.0 74000.0 0.06 3190900.0 -206000.0 -0.16 -0.0717 -0.4089 3634328 CBKinase1_024526 Cc1cccc(C)c1OCC(=O)Nc2ccc(cc2O)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O11 mock treatment 4392145.0 856000.0 0.72 4337646.0 941000.0 0.75 1.041 0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O12 mock treatment 3412916.0 -123000.0 -0.1 3987105.0 591000.0 0.47 0.2594 0.5381 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O13 compound treatment 3869519.0 333000.0 0.28 4038213.0 642000.0 0.51 0.5605 0.9603 3634329 CBKinase1_024527 CCC(=O)N1CCN(CC1)c2ccc(Cl)cc2NC(=O)COc3cc(C)c(Cl)c(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O14 compound treatment 4356934.0 821000.0 0.69 4648320.0 1250000.0 1.0 1.1951 0.9841 3634330 CBKinase1_024528 Cc1cc(nc(SCC(=O)Nc2ccc(I)cc2)n1)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O15 compound treatment 4740887.0 1200000.0 1.02 3941478.0 545000.0 0.43 1.0258 0.9281 3634331 CBKinase1_024529 CN(Cc1nc(no1)c2ccncc2)S(=O)(=O)c3ccc(Br)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O16 compound treatment 4721841.0 1190000.0 1.0 4435802.0 1040000.0 0.83 1.293 0.9956 3634332 CBKinase1_024530 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(I)cc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O17 compound treatment 5131437.0 1600000.0 1.35 5012874.0 1620000.0 1.29 1.8625 0.9998 3634333 CBKinase1_024531 COc1ccc(NC(=O)C(=O)NCC(=O)Nc2ccc(C)cc2)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O18 compound treatment 4294270.0 758000.0 0.64 4859013.0 1460000.0 1.17 1.2765 0.96 3634334 CBKinase1_024532 COc1ccccc1NC(=O)CNC(=O)c2ccc(cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O19 compound treatment 5277093.0 1740000.0 1.47 4667071.0 1270000.0 1.01 1.7545 0.9835 3634335 CBKinase1_024533 CC(Oc1ccccc1C)c2nc(no2)c3ccccn3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O20 compound treatment 4763554.0 1230000.0 1.04 4000357.0 604000.0 0.48 1.0725 0.9393 3634336 CBKinase1_024534 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3cc4cc(Br)ccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O21 compound treatment 5208622.0 1670000.0 1.41 4876504.0 1480000.0 1.18 1.8317 0.996 3634337 CBKinase1_024535 CCOc1ccc(cc1)c2nnc(SCC(=O)c3ccccc3N)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O22 compound treatment 4376458.0 840000.0 0.71 5380211.0 1980000.0 1.58 1.6193 0.9345 3634338 CBKinase1_024536 CCOC(=O)c1c(C)c(sc1NC(=S)NC(=O)c2ccc3OCCOc3c2)C(=O)OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O23 compound treatment 678885.0 -2860000.0 -2.41 577996.0 -2820000.0 -2.25 -3.2926 -0.9994 3634339 CBKinase1_024537 Oc1ccc(CSc2nnc(c3ccc(Cl)cc3)n2c4ccccc4)c5cccnc15 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 O24 compound treatment 3391465.0 -145000.0 -0.12 3524897.0 128000.0 0.1 -0.0139 -0.0872 3041539 CBKinase1_024538 Cn1cnc2cc(NCc3ccccn3)ccc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P01 compound treatment 3220565.0 -316000.0 -0.27 3318005.0 -78400.0 -0.06 -0.2324 -0.8501 3634340 CBKinase1_024539 Clc1ccccc1CSCC(=O)Nc2c[nH]c(=O)[nH]c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P02 compound treatment 3230406.0 -306000.0 -0.26 2766975.0 -629000.0 -0.5 -0.5371 -0.9521 3634341 CBKinase1_024540 Nc1ncnc2n(CCNCCc3ccccc3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P03 compound treatment 2944435.0 -592000.0 -0.5 2290823.0 -1110000.0 -0.88 -0.976 -0.9637 3634342 CBKinase1_024541 COC(=O)C1=C(C)Nc2ncnn2C1c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P04 compound treatment 2882515.0 -654000.0 -0.55 2482044.0 -914000.0 -0.73 -0.9052 -0.9905 3634343 CBKinase1_024542 COC(=O)C1=NN(C2C1C(=O)N(C3CCCCC3)C2=O)C(C)(C)CC(=O)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P05 compound treatment 3172602.0 -364000.0 -0.31 3530759.0 134000.0 0.11 -0.1411 -0.4345 3634344 CBKinase1_024543 OC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P06 compound treatment 3396721.0 -139000.0 -0.12 3900006.0 504000.0 0.4 0.2007 0.4798 3634345 CBKinase1_024544 CC(C(=O)NCc1ccco1)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P07 compound treatment 3728405.0 192000.0 0.16 3190421.0 -206000.0 -0.16 -0.0014 -0.0062 3634346 CBKinase1_024545 CCn1c(SCc2nc(no2)c3ccc(Br)cc3)nnc1c4c[nH]c5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P08 compound treatment 3529541.0 -6580.0 -0.01 3505188.0 109000.0 0.09 0.0574 0.6604 3634347 CBKinase1_024546 FC(F)(F)c1nn(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3)c4CCCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P09 compound treatment 3298263.0 -238000.0 -0.2 3164035.0 -232000.0 -0.19 -0.2729 -0.9992 3634348 CBKinase1_024547 CC(C)c1ccc(cc1)n2nc3cc(C)c(NC(=O)COc4ccccc4[N+](=O)[O-])cc3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P10 compound treatment 2167080.0 -1370000.0 -1.15 2013653.0 -1380000.0 -1.1 -1.5959 -0.9997 3634349 CBKinase1_024548 COc1ccc(Cl)cc1CN2CCC(CNC(=O)Nc3cccc(Cl)c3)CC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P11 mock treatment 3330577.0 -206000.0 -0.17 3120833.0 -276000.0 -0.22 -0.2779 -0.9931 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P12 mock treatment 3412739.0 -123000.0 -0.1 3159788.0 -237000.0 -0.19 -0.207 -0.9607 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P13 compound treatment 3307018.0 -229000.0 -0.19 3308863.0 -87600.0 -0.07 -0.186 -0.9053 3634350 CBKinase1_024549 CCCc1nnc(NC(=O)c2nc(SC)ncc2Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P14 compound treatment 3646887.0 111000.0 0.09 3501104.0 105000.0 0.08 0.125 0.9984 3634351 CBKinase1_024550 Cc1c(Br)c(nn1CC(=O)n2cccn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P15 compound treatment 3510048.0 -26100.0 -0.02 3332984.0 -63500.0 -0.05 -0.0513 -0.9304 3634352 CBKinase1_024551 Cc1cc(C)c2oc(nc2c1)c3cccc(NC(=O)COc4ccccc4Cl)c3C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P16 compound treatment 3909385.0 373000.0 0.31 3782162.0 386000.0 0.31 0.44 0.9999 1722320 CBKinase1_024552 Cn1c(=O)n(C)c2nc(NCCN)n(Cc3ccc(Cl)cc3)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P17 compound treatment 4012261.0 476000.0 0.4 3408782.0 12300.0 0.01 0.2909 0.7242 3634353 CBKinase1_024553 Clc1ccc2OCC(=O)N(CC(=O)Nc3ccc(cc3)N4CCOCC4)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P18 compound treatment 4075231.0 539000.0 0.45 4029521.0 633000.0 0.5 0.6783 0.9987 3634354 CBKinase1_024554 [O-][N+](=O)c1ccn(CC(=O)NCc2cccnc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P19 compound treatment 4316940.0 781000.0 0.66 4738618.0 1340000.0 1.07 1.2222 0.9729 3634355 CBKinase1_024555 Clc1ccc(NC(=O)NCCOc2nc(nc(n2)N3CCOCC3)N4CCOCC4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P20 compound treatment 4587295.0 1050000.0 0.89 4785349.0 1390000.0 1.11 1.4097 0.9939 3634356 CBKinase1_024556 Cc1ccccc1NC(=O)CSc2nc(Nc3ccccc3)nc(n2)N4CCOCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P21 compound treatment 4487079.0 951000.0 0.8 4719832.0 1320000.0 1.05 1.313 0.9909 3634357 CBKinase1_024557 COc1ccc(OC)c(NC(=O)CSc2nnc(s2)c3cccnc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P22 compound treatment 4501260.0 965000.0 0.81 5016654.0 1620000.0 1.29 1.4888 0.9753 3634358 CBKinase1_024558 CCOc1ccc(cc1)n2nc3ccc(NC(=O)COc4ccccc4Cl)cc3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P23 compound treatment 3813010.0 277000.0 0.23 4492252.0 1100000.0 0.87 0.7827 0.8658 3634359 CBKinase1_024559 CC(=O)c1cccc(NC(=O)Cn2ccc(n2)[N+](=O)[O-])c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2400 P24 compound treatment 3443516.0 -92600.0 -0.08 3872841.0 476000.0 0.38 0.2133 0.5501 3634360 CBKinase1_024560 CCOC(=O)c1sc(NC(=O)C(C)(C)Oc2ccc(Cl)cc2)c(C#N)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A01 compound treatment 2944084.0 -570000.0 -0.48 1407114.0 -2120000.0 -1.69 -1.532 -0.8739 3634361 CBKinase1_024561 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccco5)ncnc4c3cc2CO1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A02 compound treatment 4036863.0 523000.0 0.44 3101241.0 -421000.0 -0.34 0.0746 0.1346 3634362 CBKinase1_024562 CSc1ccccc1NC(=O)C(C)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A03 compound treatment 3422348.0 -91600.0 -0.08 2957980.0 -564000.0 -0.45 -0.3727 -0.8166 3634363 CBKinase1_024563 Cc1nn(C(=O)Cn2ccc(n2)[N+](=O)[O-])c(C)c1Br 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A04 compound treatment 4226410.0 712000.0 0.6 2762837.0 -759000.0 -0.61 -0.0031 -0.0036 3634364 CBKinase1_024564 CC(C(=O)Nc1ccc(F)c(Cl)c1)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A05 compound treatment 3628122.0 114000.0 0.1 3811875.0 290000.0 0.23 0.2313 0.9248 1849999 CBKinase1_024565 Cn1c2ccccc2c3nnc(SCC(=O)c4ccc(Cl)cc4)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A06 compound treatment 2570739.0 -943000.0 -0.8 3323325.0 -199000.0 -0.16 -0.6747 -0.8317 3634365 CBKinase1_024566 COc1ccc(cc1)C(=O)NCCCSc2nc(cc(n2)C(F)(F)F)C(C)(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A07 compound treatment 3218412.0 -296000.0 -0.25 2551755.0 -970000.0 -0.77 -0.7232 -0.8899 3634366 CBKinase1_024567 CCOc1c(Cl)c(Cl)ccc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A08 compound treatment 4621874.0 1110000.0 0.93 3461670.0 -60600.0 -0.05 0.6267 0.6697 3634367 CBKinase1_024568 [O-][N+](=O)c1ccn(CC(=O)Nc2ccc(F)c(Cl)c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A09 compound treatment 3687941.0 174000.0 0.15 3869334.0 347000.0 0.28 0.2994 0.956 3634368 CBKinase1_024569 OC(=O)c1ccccc1SCC(=O)Nc2ccnc3ccccc23 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A10 compound treatment 3612564.0 98600.0 0.08 3351104.0 -171000.0 -0.14 -0.0376 -0.2356 3634369 CBKinase1_024570 CCOc1ccc(Oc2nc(Nc3ccc(C)cc3)nc(n2)N(C)C)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A11 compound treatment 3665956.0 152000.0 0.13 3319002.0 -203000.0 -0.16 -0.0239 -0.1156 3634370 CBKinase1_024571 Cc1cccc(c1C)n2c(SCCC(=O)O)nnc2c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A12 compound treatment 3375590.0 -138000.0 -0.12 3408706.0 -114000.0 -0.09 -0.1465 -0.9921 3634371 CBKinase1_024572 CCc1ccc(cc1)n2nc3cc(C)c(NC(=O)COc4ccccc4[N+](=O)[O-])cc3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A13 mock treatment 3805375.0 291000.0 0.25 3874736.0 352000.0 0.28 0.3725 0.9978 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A14 mock treatment 3462283.0 -51700.0 -0.04 3791631.0 269000.0 0.21 0.121 0.5523 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A15 compound treatment 3726282.0 212000.0 0.18 3531966.0 9720.0 0.01 0.1321 0.737 3634372 CBKinase1_024573 COc1cc(C)c(Br)cc1S(=O)(=O)NCCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A16 compound treatment 3919673.0 406000.0 0.34 4031355.0 509000.0 0.41 0.5289 0.9964 3634373 CBKinase1_024574 FC(F)(F)c1nc(SCC(=O)Nc2ccccc2)nc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A17 compound treatment 3998804.0 485000.0 0.41 3519608.0 -2640.0 0.0 0.2877 0.7035 3634374 CBKinase1_024575 Cc1cc(I)ccc1NC(=O)Cn2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A18 compound treatment 4299159.0 785000.0 0.66 4072988.0 551000.0 0.44 0.7787 0.98 3634375 CBKinase1_024576 Cc1cc(C)n(n1)c2nc3cc(C)ccc3nc2N4CCNCC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A19 compound treatment 3883112.0 369000.0 0.31 3013169.0 -509000.0 -0.41 -0.0667 -0.1305 3040067 CBKinase1_024577 CC1CC(=O)c2c(C)nc(NCc3ccco3)nc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A20 compound treatment 3805369.0 291000.0 0.25 2919198.0 -603000.0 -0.48 -0.1661 -0.3076 3634376 CBKinase1_024578 CCOC(=O)c1ccc(NC(=O)Cn2cc(cn2)[N+](=O)[O-])cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A21 compound treatment 3630961.0 117000.0 0.1 2920973.0 -601000.0 -0.48 -0.2691 -0.5499 3634377 CBKinase1_024579 Cc1c(Br)c(nn1CC(=O)Nc2sc3CCCc3c2C#N)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A22 compound treatment 3551458.0 37500.0 0.03 3487299.0 -34900.0 -0.03 0.0027 0.0635 3122860 CBKinase1_024580 Cn1c2ccccc2c3nnc(SCCCC(=O)c4ccc5OCCOc5c4)nc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A23 compound treatment 3163804.0 -350000.0 -0.3 2899992.0 -622000.0 -0.5 -0.5595 -0.9693 3634378 CBKinase1_024581 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2ccccc2c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 A24 compound treatment 2821393.0 -693000.0 -0.58 2621883.0 -900000.0 -0.72 -0.9205 -0.9948 3634379 CBKinase1_024582 Sc1nnc(Cn2c(nc3ccccc23)c4ccccn4)n1c5cc(Cl)cc(Cl)c5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B01 compound treatment 3366477.0 -147000.0 -0.12 2220399.0 -1300000.0 -1.04 -0.8217 -0.7862 3634380 CBKinase1_024583 Clc1ccc(NC(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B02 mock treatment 2735290.0 -779000.0 -0.66 3468512.0 -53700.0 -0.04 -0.4947 -0.7516 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B03 compound treatment 4512416.0 998000.0 0.84 3765254.0 243000.0 0.19 0.7325 0.8476 3634381 CBKinase1_024584 COc1ccc(cc1OC)c2cc(nc(SCC(=O)N)n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B04 mock treatment 3709189.0 195000.0 0.16 3814513.0 292000.0 0.23 0.2812 0.9856 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B05 compound treatment 3454782.0 -59200.0 -0.05 3943871.0 422000.0 0.34 0.2023 0.5956 3634382 CBKinase1_024585 CCc1nc(OCc2ccco2)c3sc4nc5CC(C)(C)OCc5cc4c3n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B06 mock treatment 3330699.0 -183000.0 -0.15 4798798.0 1280000.0 1.02 0.6102 0.5929 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B07 compound treatment 3374191.0 -140000.0 -0.12 4284214.0 762000.0 0.61 0.3461 0.5594 3634383 CBKinase1_024586 Cn1c(=O)n(C)c2nc(NCCN3CCOCC3)n(Cc4ccc(Cl)cc4Cl)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B08 mock treatment 3323473.0 -190000.0 -0.16 3681323.0 159000.0 0.13 -0.024 -0.117 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B09 compound treatment 3676161.0 162000.0 0.14 3780794.0 259000.0 0.21 0.2425 0.9802 3634384 CBKinase1_024587 CC(O)CNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3cccc(C)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B10 mock treatment 4209018.0 695000.0 0.59 3657531.0 135000.0 0.11 0.4908 0.8233 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B11 compound treatment 3490453.0 -23500.0 -0.02 3487749.0 -34500.0 -0.03 -0.0335 -0.9871 3634385 CBKinase1_024588 COc1ccc(cc1C(=O)Nc2ccc(cc2)S(=O)(=O)C(F)F)S(=O)(=O)N3CCOCC3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B12 mock treatment 3782337.0 268000.0 0.23 3887228.0 365000.0 0.29 0.3658 0.9923 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B13 mock treatment 4066513.0 553000.0 0.47 3910152.0 388000.0 0.31 0.5482 0.9801 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B14 mock treatment 3946674.0 433000.0 0.37 4542266.0 1020000.0 0.81 0.833 0.9347 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B15 compound treatment 3670859.0 157000.0 0.13 4179638.0 657000.0 0.52 0.4641 0.8588 3634386 CBKinase1_024589 COc1ccc(cc1)n2c(SCCCN3C(=O)c4cccc5cccc(C3=O)c45)nnc2c6ccncc6 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B16 mock treatment 3696308.0 182000.0 0.15 3738912.0 217000.0 0.17 0.2309 0.9983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B17 compound treatment 3899510.0 386000.0 0.33 3695735.0 173000.0 0.14 0.3277 0.9274 3634387 CBKinase1_024590 COc1ccc(cc1OC)C(=O)CC2(O)C(=O)N(Cc3ccccc3Cl)c4ccc(Cl)cc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B18 mock treatment 4371603.0 858000.0 0.72 4237683.0 715000.0 0.57 0.9148 0.9931 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B19 compound treatment 4042458.0 529000.0 0.45 2967096.0 -555000.0 -0.44 0.0023 0.0037 3634388 CBKinase1_024591 COc1cc2c(cc1NC(=O)c3nc4ncccn4n3)oc5ccccc52 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B20 mock treatment 3153131.0 -361000.0 -0.3 4011676.0 489000.0 0.39 0.0606 0.1225 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B21 compound treatment 4034527.0 521000.0 0.44 3933091.0 411000.0 0.33 0.542 0.9896 3634389 CBKinase1_024592 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)c3c(C)onc3c4ccccc4Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B22 mock treatment 4276680.0 763000.0 0.64 4032904.0 511000.0 0.41 0.7427 0.9756 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B23 compound treatment 3615095.0 101000.0 0.09 3401537.0 -121000.0 -0.1 -0.0077 -0.0599 3634390 CBKinase1_024593 Cc1cccc(NC(=O)c2ccccc2NC(=O)COc3cccc(c3)[N+](=O)[O-])c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 B24 mock treatment 3251056.0 -263000.0 -0.22 3279079.0 -243000.0 -0.19 -0.2938 -0.9977 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C01 compound treatment 2804697.0 -709000.0 -0.6 2557318.0 -965000.0 -0.77 -0.9669 -0.9923 3634391 CBKinase1_024594 CCOc1ccccc1c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C02 compound treatment 2790233.0 -724000.0 -0.61 2618945.0 -903000.0 -0.72 -0.9408 -0.9966 3041257 CBKinase1_024595 CSc1ncc(Cl)c(n1)C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C03 compound treatment 3302434.0 -212000.0 -0.18 2875430.0 -647000.0 -0.52 -0.4907 -0.8995 1864393 CBKinase1_024596 Cn1c(=O)[nH]c(=O)c2n(CC(=O)NCc3ccccc3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C04 compound treatment 2962868.0 -551000.0 -0.46 2598297.0 -924000.0 -0.74 -0.8494 -0.9754 3634392 CBKinase1_024597 CCOC(=O)c1c(C)c(C)sc1NC(=O)C(C)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C05 compound treatment 3185269.0 -329000.0 -0.28 3817154.0 295000.0 0.24 -0.0298 -0.0821 3634393 CBKinase1_024598 CCOC(=O)COc1ccc(cc1OC)c2nc3n(C)c(=O)n(C)c(=O)c3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C06 compound treatment 3585266.0 71300.0 0.06 3153243.0 -369000.0 -0.29 -0.1654 -0.5511 3634394 CBKinase1_024599 CSc1ncc(Cl)c(n1)C(=O)Nc2nnc(SC/C=C/c3ccccc3)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C07 compound treatment 3273042.0 -241000.0 -0.2 3281384.0 -241000.0 -0.19 -0.2794 -0.9996 3634396 CBKinase1_024600 CC(c1ccccc1)n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C08 compound treatment 3550113.0 36200.0 0.03 3382720.0 -140000.0 -0.11 -0.0571 -0.4949 3634397 CBKinase1_024601 CC(C(=O)Nc1ccccc1C(F)(F)F)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C09 compound treatment 3792993.0 279000.0 0.24 3507076.0 -15200.0 -0.01 0.1579 0.6699 3634398 CBKinase1_024602 Cc1cc(nn1CC(=O)N2CCOCC2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C10 compound treatment 3154682.0 -359000.0 -0.3 3379577.0 -143000.0 -0.11 -0.2947 -0.9105 3634399 CBKinase1_024603 COc1ccc(cc1)C2=NOC(C2)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C11 mock treatment 3680361.0 166000.0 0.14 3683337.0 161000.0 0.13 0.19 0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C12 mock treatment 3582368.0 68400.0 0.06 3325287.0 -197000.0 -0.16 -0.0702 -0.4197 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C13 compound treatment 3999848.0 486000.0 0.41 3854587.0 332000.0 0.26 0.4771 0.9777 1690774 CBKinase1_024604 CCCSc1nnc(NC(=O)c2nc(SC)ncc2Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C14 compound treatment 3170937.0 -343000.0 -0.29 3287157.0 -235000.0 -0.19 -0.3371 -0.9779 3634400 CBKinase1_024605 Cn1cnnc1SCCCN2C(=O)c3cccc4cccc(C2=O)c34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C15 mock treatment 3981828.0 468000.0 0.39 3902548.0 380000.0 0.3 0.4934 0.9915 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C16 mock treatment 3843945.0 330000.0 0.28 4054407.0 532000.0 0.42 0.4967 0.9791 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C17 compound treatment 4049305.0 535000.0 0.45 3837216.0 315000.0 0.25 0.4968 0.9616 1714226 CBKinase1_024606 CCOC(=O)c1ccc2nc(C)c(CN3CCN(C)CC3)c(O)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C18 compound treatment 4144672.0 631000.0 0.53 3342561.0 -180000.0 -0.14 0.2749 0.499 3634401 CBKinase1_024607 [O-][N+](=O)c1ccn(CC(=O)Nc2cc(Cl)cc(Cl)c2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C19 compound treatment 3602142.0 88200.0 0.07 3368874.0 -153000.0 -0.12 -0.0338 -0.2365 3634402 CBKinase1_024608 Cc1nn(CC(=O)Nc2ccc(C#N)cc2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C20 compound treatment 3600947.0 87000.0 0.07 3316597.0 -206000.0 -0.16 -0.064 -0.3564 3634403 CBKinase1_024609 Nc1nc(CN2CCN(CC2)C(=O)c3ccco3)nc(n1)N4CCCc5ccccc45 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C21 compound treatment 3443022.0 -70900.0 -0.06 3083401.0 -439000.0 -0.35 -0.2896 -0.8162 3034920 CBKinase1_024610 Cc1cc2nsnc2c(c1C)S(=O)(=O)N3CCN=C3Cc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C22 compound treatment 3493092.0 -20900.0 -0.02 3235512.0 -287000.0 -0.23 -0.174 -0.7593 3634404 CBKinase1_024611 CCOc1c(Cl)c(Cl)ccc1S(=O)(=O)NCc2cccnc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C23 compound treatment 2914079.0 -600000.0 -0.51 2826098.0 -696000.0 -0.55 -0.7501 -0.9989 3634405 CBKinase1_024612 CC(C)N(Cc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3ccc(F)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 C24 compound treatment 2644549.0 -869000.0 -0.73 2464397.0 -1060000.0 -0.84 -1.1147 -0.9976 3634406 CBKinase1_024613 Cc1ccc(cc1NC(=O)COc2ccccc2Cl)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D01 compound treatment 2655370.0 -859000.0 -0.72 2327249.0 -1190000.0 -0.95 -1.1856 -0.9909 3634407 CBKinase1_024614 CSc1nsc(SCCN2C(=O)c3ccccc3C2=O)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D02 mock treatment 2977958.0 -536000.0 -0.45 3035629.0 -487000.0 -0.39 -0.5939 -0.9971 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D03 compound treatment 3343884.0 -170000.0 -0.14 2657074.0 -865000.0 -0.69 -0.589 -0.8363 3040113 CBKinase1_024615 O=c1n([nH]c2[nH]c(CSc3nnnn3c4ccccc4)cc(=O)c12)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D04 mock treatment 3431182.0 -82800.0 -0.07 3203364.0 -319000.0 -0.25 -0.2291 -0.8691 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D05 compound treatment 3483309.0 -30600.0 -0.03 3164448.0 -358000.0 -0.29 -0.2199 -0.768 3634408 CBKinase1_024616 Cc1cc2nn(nc2cc1NC(=S)NC(=O)COc3ccccc3)c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D06 mock treatment 3701677.0 188000.0 0.16 3451492.0 -70800.0 -0.06 0.0721 0.4289 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D07 compound treatment 3675429.0 161000.0 0.14 4031147.0 509000.0 0.41 0.3831 0.8954 3634409 CBKinase1_024617 O=C(CSc1ccc2ccccc2n1)Nc3ccnc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D08 mock treatment 3874545.0 361000.0 0.3 3792362.0 270000.0 0.22 0.3673 0.9857 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D09 compound treatment 2504324.0 -1010000.0 -0.85 2491064.0 -1030000.0 -0.82 -1.1834 -0.9998 3634410 CBKinase1_024618 COc1ccc(C)cc1CN2CCC(CNC(=O)Nc3cc(Cl)ccc3C)CC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D10 mock treatment 3533856.0 19900.0 0.02 3617307.0 95100.0 0.08 0.0655 0.8434 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D11 mock treatment 3700121.0 186000.0 0.16 3996635.0 474000.0 0.38 0.3784 0.9242 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D12 mock treatment 3833765.0 320000.0 0.27 3758356.0 236000.0 0.19 0.3238 0.9845 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D13 compound treatment 4030908.0 517000.0 0.44 4213669.0 691000.0 0.55 0.698 0.9933 3634411 CBKinase1_024619 Cc1cc(C)c(NC(=O)C(CCS(=O)(=O)C)N2C(=O)c3ccc(Br)cc3C2=O)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D14 mock treatment 3985801.0 472000.0 0.4 3557331.0 35100.0 0.03 0.3012 0.7549 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D15 mock treatment 3902492.0 389000.0 0.33 4517618.0 995000.0 0.79 0.7927 0.9235 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D16 mock treatment 4230213.0 716000.0 0.6 3681627.0 159000.0 0.13 0.517 0.8375 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D17 compound treatment 4109010.0 595000.0 0.5 3976164.0 454000.0 0.36 0.6107 0.9871 3634412 CBKinase1_024620 COc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)Nc4cccc(NC(=O)C)c4)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D18 mock treatment 4026229.0 512000.0 0.43 4006575.0 484000.0 0.39 0.5785 0.9984 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D19 compound treatment 3715362.0 201000.0 0.17 3586746.0 64500.0 0.05 0.1565 0.8816 3634413 CBKinase1_024621 CCN(CC(=O)O)S(=O)(=O)c1ccc(F)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D20 mock treatment 3890150.0 376000.0 0.32 3722114.0 200000.0 0.16 0.337 0.9492 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D21 compound treatment 3458924.0 -55000.0 -0.05 3153282.0 -369000.0 -0.29 -0.2408 -0.8087 2899 CBKinase1_024622 COc1ccc(cc1)c2noc(CC(=O)O)c2c3ccc(OC)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D22 mock treatment 3431314.0 -82600.0 -0.07 3087546.0 -435000.0 -0.35 -0.2943 -0.8327 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D23 compound treatment 3417198.0 -96700.0 -0.08 2848794.0 -673000.0 -0.54 -0.4373 -0.8054 3634414 CBKinase1_024623 CCc1cccc(NC(=O)CSc2c(C)n[nH]c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 D24 mock treatment 2765062.0 -749000.0 -0.63 2625172.0 -897000.0 -0.72 -0.9523 -0.9981 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E01 mock treatment 933646.0 -2580000.0 -2.18 870314.0 -2650000.0 -2.11 -3.0336 -0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E02 mock treatment 1223746.0 -2290000.0 -1.93 1075862.0 -2450000.0 -1.95 -2.7447 -1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E03 compound treatment 1216727.0 -2300000.0 -1.94 1050262.0 -2470000.0 -1.97 -2.7634 -1.0 3634415 CBKinase1_024624 CCSc1ncc(Cl)c(n1)C(=O)Nc2nnc(SCc3ccccc3F)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E04 compound treatment 1478461.0 -2040000.0 -1.72 1223366.0 -2300000.0 -1.83 -2.5097 -0.9995 3634416 CBKinase1_024625 Cc1cc(nn1CC(=O)Nc2cc(Cl)cc(Cl)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E05 compound treatment 1626527.0 -1890000.0 -1.59 4309534.0 787000.0 0.63 -0.682 -0.3986 3634417 CBKinase1_024626 COc1ccc(cc1NC(=O)COc2ccc(cc2)C(C)C)c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E06 compound treatment 3849712.0 336000.0 0.28 1396236.0 -2130000.0 -1.69 -0.9979 -0.5809 3634418 CBKinase1_024627 [O-][N+](=O)c1ccn(CC(=O)N2CCCc3ccccc23)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E07 compound treatment 2517408.0 -997000.0 -0.84 2721843.0 -800000.0 -0.64 -1.0455 -0.9907 3634419 CBKinase1_024628 COc1ccc(NC(=O)CSc2nc(C)c3CCCCc3n2)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E08 compound treatment 2864688.0 -649000.0 -0.55 2378171.0 -1140000.0 -0.91 -1.032 -0.9702 3634420 CBKinase1_024629 COc1ccc(Cl)c(Cn2c(NCc3ccco3)nc4n(C)c(=O)n(C)c(=O)c24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E09 mock treatment 2306622.0 -1210000.0 -1.02 2190002.0 -1330000.0 -1.06 -1.4709 -0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E10 mock treatment 2422987.0 -1090000.0 -0.92 2854044.0 -668000.0 -0.53 -1.0273 -0.9662 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E11 compound treatment 2658319.0 -856000.0 -0.72 2494787.0 -1030000.0 -0.82 -1.0894 -0.998 3634421 CBKinase1_024630 Nc1nn(cc1c2ccc(Br)cc2)S(=O)(=O)c3cccc4nsnc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E12 compound treatment 2707480.0 -806000.0 -0.68 2803843.0 -718000.0 -0.57 -0.8859 -0.9963 3634422 CBKinase1_024631 Cn1nnnc1SCCNC/C=C/c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E13 compound treatment 2944801.0 -569000.0 -0.48 2605608.0 -917000.0 -0.73 -0.8561 -0.9793 3634424 CBKinase1_024632 COCCNC(=O)c1c(NC(=O)c2nc(SC)ncc2Cl)sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E14 compound treatment 2812797.0 -701000.0 -0.59 2663871.0 -858000.0 -0.68 -0.902 -0.9974 3634425 CBKinase1_024633 O=c1[nH]c(SCc2n[nH]c(=S)n2c3ccccc3)nc4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E15 compound treatment 2734536.0 -779000.0 -0.66 2816717.0 -706000.0 -0.56 -0.8625 -0.997 3634426 CBKinase1_024634 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2cccc(c2)c3nc4ncccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E16 compound treatment 3129081.0 -385000.0 -0.32 2804499.0 -718000.0 -0.57 -0.6341 -0.964 3634427 CBKinase1_024635 Cc1cc2nn(nc2cc1NC(=O)C(C)(C)Oc3ccc(Cl)cc3)c4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E17 mock treatment 3020214.0 -494000.0 -0.42 2882582.0 -640000.0 -0.51 -0.655 -0.995 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E18 mock treatment 3013928.0 -500000.0 -0.42 3346521.0 -176000.0 -0.14 -0.3973 -0.8939 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E19 compound treatment 2198798.0 -1320000.0 -1.11 2504523.0 -1020000.0 -0.81 -1.358 -0.9882 3634428 CBKinase1_024636 CCOC(=O)c1c(C)c(C)sc1NC(=O)C(C)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E20 compound treatment 2937212.0 -577000.0 -0.49 2591848.0 -930000.0 -0.74 -0.8684 -0.9791 3634429 CBKinase1_024637 CC(=O)c1ccc(NC(=O)Cn2cnc3c4cc5COC(C)(C)Cc5nc4sc3c2=O)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E21 compound treatment 2723768.0 -790000.0 -0.67 2813447.0 -709000.0 -0.56 -0.8708 -0.9966 3634430 CBKinase1_024638 Cc1onc(c1C(=O)N(Cc2nc(no2)c3ccccc3)C4CCCCC4)c5ccccc5Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E22 compound treatment 2707327.0 -807000.0 -0.68 2683134.0 -839000.0 -0.67 -0.954 -1.0 3634431 CBKinase1_024639 OC(CNC(=O)c1cccc(c1)S(=O)(=O)N2CCOCC2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E23 compound treatment 2026519.0 -1490000.0 -1.25 2359871.0 -1160000.0 -0.93 -1.5423 -0.9889 3634432 CBKinase1_024640 COc1ccccc1C(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4ccco4)c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 E24 compound treatment 2128982.0 -1380000.0 -1.17 2104770.0 -1420000.0 -1.13 -1.6249 -0.9999 3634433 CBKinase1_024641 CCCOc1ccc(Oc2nc(Nc3ccc(C)cc3)nc(n2)N4CCOCC4)nn1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F01 mock treatment 1230958.0 -2280000.0 -1.93 927423.0 -2590000.0 -2.07 -2.8241 -0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F02 mock treatment 1778200.0 -1740000.0 -1.46 1778538.0 -1740000.0 -1.39 -2.018 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F03 compound treatment 2431088.0 -1080000.0 -0.91 1666921.0 -1860000.0 -1.48 -1.6915 -0.9732 3634434 CBKinase1_024642 COc1ccccc1c2cc(C(F)F)n3ncc(C(=O)NCc4cccnc4)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F04 mock treatment 2873207.0 -641000.0 -0.54 1580929.0 -1940000.0 -1.55 -1.4763 -0.9007 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F05 compound treatment 2482205.0 -1030000.0 -0.87 1945948.0 -1580000.0 -1.26 -1.5038 -0.9839 3634435 CBKinase1_024643 Cc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)NCc4ccco4)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F06 mock treatment 3762156.0 248000.0 0.21 1515432.0 -2010000.0 -1.6 -0.983 -0.6094 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F07 compound treatment 2957964.0 -556000.0 -0.47 1746709.0 -1780000.0 -1.42 -1.3323 -0.8936 3634436 CBKinase1_024644 Cc1c(Br)c(nn1CC(=O)Nc2cc(C)ccc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F08 mock treatment 3470118.0 -43800.0 -0.04 1892694.0 -1630000.0 -1.3 -0.9445 -0.7269 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F09 mock treatment 2052125.0 -1460000.0 -1.23 1886884.0 -1640000.0 -1.3 -1.7936 -0.9996 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F10 mock treatment 2046253.0 -1470000.0 -1.24 2075564.0 -1450000.0 -1.15 -1.6907 -0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F11 compound treatment 2152036.0 -1360000.0 -1.15 2390051.0 -1130000.0 -0.9 -1.4504 -0.9929 3634437 CBKinase1_024645 CSc1ccccc1NC(=O)C(C)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F12 mock treatment 2486717.0 -1030000.0 -0.87 2648639.0 -874000.0 -0.7 -1.105 -0.9941 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F13 compound treatment 2433387.0 -1080000.0 -0.91 2191628.0 -1330000.0 -1.06 -1.3944 -0.9972 3634438 CBKinase1_024646 Cc1ccccc1Nc2nc(N)nc(CN3CCN(CC3)c4ccccn4)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F14 mock treatment 2617246.0 -897000.0 -0.76 2224779.0 -1300000.0 -1.03 -1.2661 -0.9882 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F15 compound treatment 2642293.0 -872000.0 -0.74 2313301.0 -1210000.0 -0.96 -1.2012 -0.9911 3634439 CBKinase1_024647 CCOC(=O)c1sc(NC(=O)c2nc(SC)ncc2Cl)c(C(=O)OCC)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F16 mock treatment 2686045.0 -828000.0 -0.7 2339419.0 -1180000.0 -0.94 -1.1604 -0.9891 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F17 mock treatment 2645239.0 -869000.0 -0.73 2552647.0 -970000.0 -0.77 -1.0646 -0.9996 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F18 mock treatment 2560434.0 -954000.0 -0.8 2454438.0 -1070000.0 -0.85 -1.1705 -0.9996 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F19 compound treatment 2338196.0 -1180000.0 -0.99 2277682.0 -1240000.0 -0.99 -1.4027 -1.0 3634440 CBKinase1_024648 COc1ccccc1c2cc(nc(n2)S(=O)(=O)CCCC(=O)N3CCOCC3)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F20 mock treatment 2508158.0 -1010000.0 -0.85 2289473.0 -1230000.0 -0.98 -1.2947 -0.9973 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F21 compound treatment 2190103.0 -1320000.0 -1.12 1628666.0 -1890000.0 -1.51 -1.8568 -0.989 1712282 CBKinase1_024649 Brc1ccc(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F22 mock treatment 2574615.0 -939000.0 -0.79 2433310.0 -1090000.0 -0.87 -1.174 -0.999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F23 compound treatment 2596703.0 -917000.0 -0.77 2177919.0 -1340000.0 -1.07 -1.3047 -0.9872 3634441 CBKinase1_024650 Cc1n[nH]c(C)c1SCC(=O)Nc2ccc(C)c(Cl)c2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 F24 mock treatment 2159570.0 -1350000.0 -1.14 2773683.0 -749000.0 -0.6 -1.2297 -0.9541 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G01 compound treatment 2292023.0 -1220000.0 -1.03 2043435.0 -1480000.0 -1.18 -1.5623 -0.9978 3634442 CBKinase1_024651 OC(CNC(=O)c1ccc(Cl)c(c1)S(=O)(=O)N2CCOCC2)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G02 compound treatment 2009507.0 -1500000.0 -1.27 2139221.0 -1380000.0 -1.1 -1.6768 -0.9975 3634443 CBKinase1_024652 Cc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)N4CCCCC4c5cccnc5)c3n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G03 mock treatment 4127096.0 613000.0 0.52 3033149.0 -489000.0 -0.39 0.0901 0.139 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G04 mock treatment 3365953.0 -148000.0 -0.12 2937576.0 -585000.0 -0.47 -0.4178 -0.866 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G05 compound treatment 3045480.0 -468000.0 -0.4 2926253.0 -596000.0 -0.48 -0.6153 -0.9958 3634444 CBKinase1_024653 Cn1c(SCCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1c5ccncc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G06 compound treatment 3224500.0 -289000.0 -0.24 2870589.0 -652000.0 -0.52 -0.5399 -0.9407 3634445 CBKinase1_024654 CC(C)OC(=O)C(C)Sc1ncnc2scc(c3ccc(Br)cc3)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G07 compound treatment 3821265.0 307000.0 0.26 3684068.0 162000.0 0.13 0.2745 0.9481 3634446 CBKinase1_024655 CSc1ncc(Cl)c(n1)C(=O)Nc2sc3CCCc3c2C(=O)NCC4CCCO4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G08 compound treatment 3366289.0 -148000.0 -0.12 3156721.0 -366000.0 -0.29 -0.2941 -0.9281 3634447 CBKinase1_024656 COc1ccccc1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G09 compound treatment 3170725.0 -343000.0 -0.29 2733292.0 -789000.0 -0.63 -0.6494 -0.938 3634448 CBKinase1_024657 CC(C(=O)Nc1ccc(NC(=O)C)cc1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G10 compound treatment 3304857.0 -209000.0 -0.18 3066655.0 -456000.0 -0.36 -0.3815 -0.945 3634449 CBKinase1_024658 CC(=O)C1=C(C)Nc2ncnn2C1c3ccccc3[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G11 compound treatment 3078701.0 -435000.0 -0.37 3484637.0 -37600.0 -0.03 -0.2808 -0.7623 3634450 CBKinase1_024659 O=C(NCc1nc(no1)c2ccccc2)c3ccc4ccccc4c3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G12 compound treatment 3314378.0 -200000.0 -0.17 3172619.0 -350000.0 -0.28 -0.3161 -0.9709 3634451 CBKinase1_024660 FC(F)(F)c1cc(nc(n1)S(=O)(=O)CCC(=O)Nc2ccc(Cl)cc2Cl)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G13 compound treatment 3338106.0 -176000.0 -0.15 3287362.0 -235000.0 -0.19 -0.2373 -0.9933 3634452 CBKinase1_024661 CCn1ncc(C2=NOC(C2)C(=O)Nc3ccc(Cl)c(Cl)c3)c1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G14 compound treatment 3325925.0 -188000.0 -0.16 2962242.0 -560000.0 -0.45 -0.4278 -0.903 3634453 CBKinase1_024662 Cc1ccc(OCC(=O)Nc2ccccc2N3CCN(CC3)S(=O)(=O)C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G15 compound treatment 3404600.0 -109000.0 -0.09 2702521.0 -820000.0 -0.65 -0.5272 -0.799 3634454 CBKinase1_024663 CC(C)c1ccc(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G16 compound treatment 3626592.0 113000.0 0.1 3547894.0 25600.0 0.02 0.0816 0.84 3634455 CBKinase1_024664 OC(=O)CCSc1nnc(c2cccnc2)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G17 compound treatment 3484898.0 -29000.0 -0.02 3845908.0 324000.0 0.26 0.1651 0.6371 3634456 CBKinase1_024665 Cc1cc(Br)ccc1NC(=O)Cn2cc(cn2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G18 compound treatment 3956032.0 442000.0 0.37 2458986.0 -1060000.0 -0.85 -0.3356 -0.3624 3634457 CBKinase1_024666 CCOC(=O)c1ccc(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G19 mock treatment 3782485.0 269000.0 0.23 2484524.0 -1040000.0 -0.83 -0.4247 -0.4952 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G20 mock treatment 3540887.0 26900.0 0.02 3999582.0 477000.0 0.38 0.2851 0.748 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G21 compound treatment 3483086.0 -30900.0 -0.03 2376535.0 -1150000.0 -0.91 -0.6641 -0.727 3634458 CBKinase1_024667 CCN(CC(=O)O)S(=O)(=O)c1ccc(OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G22 compound treatment 3369625.0 -144000.0 -0.12 2728406.0 -794000.0 -0.63 -0.5335 -0.828 3634459 CBKinase1_024668 COc1ccc(CCNC(=O)c2nc(SC)ncc2Cl)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G23 compound treatment 2968215.0 -546000.0 -0.46 2964741.0 -558000.0 -0.44 -0.6397 -0.9998 3634460 CBKinase1_024669 CSc1ncc(Cl)c(n1)C(=O)Nc2sc3CCCc3c2C(=O)NCCc4ccccc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 G24 compound treatment 2804744.0 -709000.0 -0.6 2958712.0 -564000.0 -0.45 -0.7406 -0.99 3634461 CBKinase1_024670 Cc1cc(nn1CC(=O)Nc2cccc(O)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H01 compound treatment 2796878.0 -717000.0 -0.6 2449180.0 -1070000.0 -0.86 -1.0325 -0.9856 3634462 CBKinase1_024671 FC(F)S(=O)(=O)c1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H02 mock treatment 3113555.0 -400000.0 -0.34 2902314.0 -620000.0 -0.49 -0.5882 -0.9828 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H03 mock treatment 2925487.0 -588000.0 -0.5 3316064.0 -206000.0 -0.16 -0.4672 -0.8935 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H04 mock treatment 3097753.0 -416000.0 -0.35 2723855.0 -798000.0 -0.64 -0.6982 -0.9607 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H05 compound treatment 3278808.0 -235000.0 -0.2 3355608.0 -167000.0 -0.13 -0.2342 -0.981 3634463 CBKinase1_024672 Cc1cc(c(C)cc1Cl)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H06 mock treatment 3349894.0 -164000.0 -0.14 3163510.0 -359000.0 -0.29 -0.3 -0.9445 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H07 compound treatment 3357219.0 -157000.0 -0.13 3377664.0 -145000.0 -0.12 -0.175 -0.9977 3634464 CBKinase1_024673 [O-][N+](=O)c1ccn(CC(=O)Nc2cc(F)ccc2F)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H08 mock treatment 3402752.0 -111000.0 -0.09 3053081.0 -469000.0 -0.37 -0.3307 -0.8579 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H09 compound treatment 3180934.0 -333000.0 -0.28 3689332.0 167000.0 0.13 -0.1045 -0.336 3634465 CBKinase1_024674 O=C(NCc1ccccn1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H10 mock treatment 3325021.0 -189000.0 -0.16 3500708.0 -21500.0 -0.02 -0.1248 -0.7788 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H11 compound treatment 3442367.0 -71600.0 -0.06 3572609.0 50400.0 0.04 -0.0143 -0.1974 3634466 CBKinase1_024675 Cc1ccccc1Cn2ccc(NC(=O)c3nn4cccnc4c3Cl)n2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H12 mock treatment 3267142.0 -247000.0 -0.21 2962305.0 -560000.0 -0.45 -0.4628 -0.9397 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H13 compound treatment 3299330.0 -215000.0 -0.18 3878266.0 356000.0 0.28 0.0726 0.2158 3634467 CBKinase1_024676 Cc1nn(CC(=O)NCc2cccnc2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H14 mock treatment 2967926.0 -546000.0 -0.46 3375832.0 -146000.0 -0.12 -0.4082 -0.8591 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H15 compound treatment 3272525.0 -241000.0 -0.2 3889437.0 367000.0 0.29 0.063 0.1766 3634468 CBKinase1_024677 Cc1cc(nn1CC(=O)Nc2ccc(Br)c(C)c2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H16 mock treatment 3744420.0 230000.0 0.19 3727900.0 206000.0 0.16 0.2534 0.9964 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H17 compound treatment 3900705.0 387000.0 0.33 2750778.0 -771000.0 -0.61 -0.2041 -0.2932 3634469 CBKinase1_024678 COc1ccc(CCNc2nc(C)nc3c4cc5COC(C)(C)Cc5nc4sc23)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H18 mock treatment 3972431.0 458000.0 0.39 2225765.0 -1300000.0 -1.03 -0.4572 -0.4144 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H19 mock treatment 3460535.0 -53400.0 -0.05 4067389.0 545000.0 0.43 0.2754 0.6304 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H20 mock treatment 3794235.0 280000.0 0.24 3110018.0 -412000.0 -0.33 -0.0652 -0.161 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H21 compound treatment 3457447.0 -56500.0 -0.05 3453436.0 -68800.0 -0.05 -0.0725 -0.9975 1274528 CBKinase1_024679 COc1ccc(Br)cc1S(=O)(=O)Nc2ccc(Cl)cn2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H22 mock treatment 3644012.0 130000.0 0.11 3285224.0 -237000.0 -0.19 -0.056 -0.2564 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H23 compound treatment 3225508.0 -288000.0 -0.24 3286541.0 -236000.0 -0.19 -0.3049 -0.9918 3634470 CBKinase1_024680 O=C(NCCCn1ccnc1)C2CCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 H24 mock treatment 2597570.0 -916000.0 -0.77 2741304.0 -781000.0 -0.62 -0.9867 -0.9942 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I01 compound treatment 3142512.0 -371000.0 -0.31 2594111.0 -928000.0 -0.74 -0.7446 -0.9269 3634471 CBKinase1_024681 Cn1c(=O)n(C)c2nc(NCCCO)n(C/C=C/c3ccccc3)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I02 compound treatment 2907549.0 -606000.0 -0.51 3503117.0 -19100.0 -0.02 -0.3725 -0.7279 3634473 CBKinase1_024682 Cn1c(NCCN)nc2n(C)c(=O)n(C)c(=O)c12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I03 compound treatment 3698829.0 185000.0 0.16 3470184.0 -52100.0 -0.04 0.0809 0.5015 3634474 CBKinase1_024683 CCSc1ncc(Cl)c(n1)C(=O)Nc2sc3CCCCc3c2C(=O)NCC4CCCO4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I04 compound treatment 3485334.0 -28600.0 -0.02 3848674.0 326000.0 0.26 0.1669 0.6388 3634475 CBKinase1_024684 Cn1nnnc1SCCNCc2ccncc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I05 mock treatment 4031251.0 517000.0 0.44 3315094.0 -207000.0 -0.17 0.1918 0.4111 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I06 mock treatment 3560073.0 46100.0 0.04 3802378.0 280000.0 0.22 0.1854 0.818 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I07 compound treatment 3712501.0 199000.0 0.17 3705905.0 184000.0 0.15 0.2219 0.9977 3634476 CBKinase1_024685 COC(=O)c1c(NC(=O)Cn2ccc(n2)[N+](=O)[O-])sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I08 compound treatment 3369734.0 -144000.0 -0.12 3649089.0 127000.0 0.1 -0.0145 -0.0918 3634477 CBKinase1_024686 COc1cc(C)c(Cl)cc1S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I09 compound treatment 3961852.0 448000.0 0.38 3515068.0 -7180.0 -0.01 0.2631 0.6963 3634478 CBKinase1_024687 CCOC(=O)c1cnc(SCC(=O)Nc2ccc(Cl)cc2Cl)nc1N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I10 compound treatment 3594994.0 81000.0 0.07 3794872.0 273000.0 0.22 0.202 0.8867 3634479 CBKinase1_024688 [O-][N+](=O)c1cnn(CC(=O)n2cc(I)cn2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I11 compound treatment 3780694.0 267000.0 0.23 3548319.0 26100.0 0.02 0.1738 0.7691 3634480 CBKinase1_024689 COc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3C)nc4ccccc4c2=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I12 compound treatment 3529647.0 15700.0 0.01 3971299.0 449000.0 0.36 0.2624 0.7328 3634481 CBKinase1_024690 CC(C(=O)Nc1cc(C)ccc1C)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I13 compound treatment 3903193.0 389000.0 0.33 3909886.0 388000.0 0.31 0.4506 0.9995 3634482 CBKinase1_024691 CCn1c(SCC(=O)Nc2ccccc2)nc3ccc(I)cc3c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I14 compound treatment 4183765.0 670000.0 0.56 3824849.0 303000.0 0.24 0.5701 0.9279 3634483 CBKinase1_024692 CSc1nnc(NC(=O)c2nc(SC)ncc2Cl)s1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I15 compound treatment 4068033.0 554000.0 0.47 4216047.0 694000.0 0.55 0.7215 0.9965 3634484 CBKinase1_024693 Cn1c(=O)[nH]c(=O)c2n(CC(=O)NCc3ccco3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I16 compound treatment 3609057.0 95100.0 0.08 3603278.0 81000.0 0.06 0.1024 0.9942 3634485 CBKinase1_024694 Cc1ccccc1OCC(=O)NC(=S)Nc2ccccc2c3nc4ccccc4s3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I17 compound treatment 4269087.0 755000.0 0.64 4042669.0 520000.0 0.41 0.7437 0.9784 3634486 CBKinase1_024695 COc1ccc(NC(=O)COc2c(Cl)c(C)c(Cl)c(C)c2Cl)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I18 compound treatment 4239926.0 726000.0 0.61 4195602.0 673000.0 0.54 0.8125 0.9978 3634487 CBKinase1_024696 CCOc1cc(c(C)cc1C)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I19 compound treatment 4165725.0 652000.0 0.55 3609207.0 87000.0 0.07 0.4378 0.79 3634488 CBKinase1_024697 CCN(CC(=O)N)S(=O)(=O)c1ccc(OC)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I20 compound treatment 4064378.0 550000.0 0.46 3841154.0 319000.0 0.25 0.508 0.9598 3038012 CBKinase1_024698 Nc1ncnc2n(CCN3CCCCC3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I21 mock treatment 3152745.0 -361000.0 -0.3 3597506.0 75300.0 0.06 -0.173 -0.5572 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I22 mock treatment 3160723.0 -353000.0 -0.3 4031911.0 510000.0 0.41 0.0766 0.152 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I23 compound treatment 2063286.0 -1450000.0 -1.22 3315391.0 -207000.0 -0.16 -0.9818 -0.7952 3634489 CBKinase1_024699 CCOc1ccc(NC(=O)C(C)n2nc([N+](=O)[O-])c(Br)c2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 I24 compound treatment 2955551.0 -558000.0 -0.47 2588224.0 -934000.0 -0.74 -0.8595 -0.9756 3634490 CBKinase1_024700 CCOc1ccc(cc1C)S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J01 compound treatment 2948189.0 -566000.0 -0.48 2726568.0 -796000.0 -0.63 -0.7859 -0.9902 3634491 CBKinase1_024701 CCOC(=O)c1cnc(Nc2nc3ccccc3s2)nc1CSc4nnc(C)s4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J02 mock treatment 3484220.0 -29700.0 -0.03 3270706.0 -252000.0 -0.2 -0.1595 -0.7894 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J03 compound treatment 3728431.0 214000.0 0.18 3527321.0 5070.0 0.0 0.1308 0.7227 3634492 CBKinase1_024702 [O-][N+](=O)c1ccc(N2CCOCC2)c(c1)C(=O)NCc3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J04 mock treatment 3296864.0 -217000.0 -0.18 3546805.0 24600.0 0.02 -0.1156 -0.6279 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J05 mock treatment 3732256.0 218000.0 0.18 3549719.0 27500.0 0.02 0.1457 0.7856 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J06 mock treatment 3499243.0 -14700.0 -0.01 3816349.0 294000.0 0.23 0.157 0.6688 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J07 compound treatment 3912897.0 399000.0 0.34 3481280.0 -41000.0 -0.03 0.2149 0.6355 3634493 CBKinase1_024703 COc1ccc2C(=CC(C)(C)N(C(=O)CSc3nnc(C)n3c4ccc(F)cc4)c2c1)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J08 mock treatment 3862270.0 348000.0 0.29 3803145.0 281000.0 0.22 0.3661 0.991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J09 compound treatment 3653848.0 140000.0 0.12 4374361.0 852000.0 0.68 0.5637 0.8177 3634494 CBKinase1_024704 Cc1cc(nn1CC(=O)NCc2ccccc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J10 mock treatment 3887180.0 373000.0 0.31 3911099.0 389000.0 0.31 0.4418 1.0 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J11 compound treatment 3585181.0 71200.0 0.06 3817108.0 295000.0 0.24 0.2087 0.8602 3634495 CBKinase1_024705 COC(=O)c1ccc(Cl)c(NC(=O)CN2CCN(Cc3ccccc3)CC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J12 mock treatment 3851271.0 337000.0 0.28 3814807.0 293000.0 0.23 0.3661 0.9951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J13 compound treatment 3839764.0 326000.0 0.27 4219794.0 698000.0 0.56 0.5875 0.9472 3634496 CBKinase1_024706 CN(C)c1nc(Nc2ccc(C)cc2)nc(Oc3ccc(O)nn3)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J14 mock treatment 4149108.0 635000.0 0.54 4111955.0 590000.0 0.47 0.7112 0.9979 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J15 compound treatment 3332480.0 -181000.0 -0.15 4209288.0 687000.0 0.55 0.279 0.4906 3634497 CBKinase1_024707 Cc1coc(C)c1C(=O)CC2(O)C(=O)N(Cc3ccc(C)cc3)c4ccc(Cl)cc42 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J16 mock treatment 4615183.0 1100000.0 0.93 4537827.0 1020000.0 0.81 1.2292 0.9976 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J17 compound treatment 4309013.0 795000.0 0.67 4696442.0 1170000.0 0.94 1.136 0.9866 3634498 CBKinase1_024708 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccc(Cl)cc3)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J18 mock treatment 4464541.0 951000.0 0.8 4172729.0 650000.0 0.52 0.9336 0.9777 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J19 compound treatment 4161128.0 647000.0 0.55 4208507.0 686000.0 0.55 0.7728 1.0 3634499 CBKinase1_024709 Cc1nn(CC(=O)Nc2cc(Cl)cc(Cl)c2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J20 mock treatment 4160505.0 647000.0 0.55 3860968.0 339000.0 0.27 0.5765 0.9474 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J21 mock treatment 4103305.0 589000.0 0.5 3734818.0 213000.0 0.17 0.4713 0.8974 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J22 mock treatment 4111304.0 597000.0 0.5 3636886.0 115000.0 0.09 0.4209 0.8219 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J23 compound treatment 3689939.0 176000.0 0.15 3587513.0 65300.0 0.05 0.1418 0.9012 3634500 CBKinase1_024710 OCCSc1nnc(c2ccccc2O)n1c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 J24 mock treatment 3380712.0 -133000.0 -0.11 3180266.0 -342000.0 -0.27 -0.2722 -0.9233 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K01 compound treatment 1581636.0 -1930000.0 -1.63 1504006.0 -2020000.0 -1.61 -2.29 -1.0 3634501 CBKinase1_024711 CSc1nsc(SCC(=O)OC2CC3CCC2(C)C3(C)C)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K02 compound treatment 1989390.0 -1520000.0 -1.29 2823944.0 -698000.0 -0.56 -1.3029 -0.9298 3634502 CBKinase1_024712 CC1(C)Cc2nc3sc4c(SCC(=O)N5CCOCC5)ncnc4c3cc2CO1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K03 compound treatment 2879742.0 -634000.0 -0.53 3594254.0 72000.0 0.06 -0.3377 -0.6276 3634503 CBKinase1_024713 COc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K04 compound treatment 2889299.0 -625000.0 -0.53 3333772.0 -188000.0 -0.15 -0.4788 -0.8739 3634504 CBKinase1_024714 [O-][N+](=O)c1ccn(CC(=O)NCc2ccccn2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K05 compound treatment 3816976.0 303000.0 0.26 3874534.0 352000.0 0.28 0.3793 0.9989 3634505 CBKinase1_024715 COc1cc(C)c(Br)cc1S(=O)(=O)NCCN2CCOCC2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K06 compound treatment 3223759.0 -290000.0 -0.24 3412608.0 -110000.0 -0.09 -0.2349 -0.9037 3634506 CBKinase1_024716 Cc1cc(C)c(NC(=O)CSc2nc(O)cc(n2)c3ccccc3)c(c1)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K07 mock treatment 3591573.0 77600.0 0.07 3610874.0 88600.0 0.07 0.0962 0.9993 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K08 mock treatment 3456696.0 -57200.0 -0.05 3276977.0 -245000.0 -0.2 -0.1724 -0.856 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K09 compound treatment 3495315.0 -18600.0 -0.02 3653671.0 131000.0 0.1 0.063 0.5944 3634507 CBKinase1_024717 COc1ccc(Cl)c(Cn2c(NCc3ccccn3)nc4n(C)c(=O)n(C)c(=O)c24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K10 compound treatment 3143421.0 -371000.0 -0.31 3071259.0 -451000.0 -0.36 -0.4752 -0.9976 3634508 CBKinase1_024718 OC1(CC(=O)c2cccnc2)C(=O)N(Cc3ccc(Cl)cc3)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K11 compound treatment 3056626.0 -457000.0 -0.39 3376194.0 -146000.0 -0.12 -0.3551 -0.8812 3634509 CBKinase1_024719 Fc1ccc(cc1Cl)n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K12 compound treatment 3175732.0 -338000.0 -0.29 3160203.0 -362000.0 -0.29 -0.4058 -1.0 3634510 CBKinase1_024720 CCOC(=O)c1c(NC(=O)C(C)n2nc([N+](=O)[O-])c(Br)c2C)sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K13 compound treatment 3383125.0 -131000.0 -0.11 3072299.0 -450000.0 -0.36 -0.3316 -0.8838 3634511 CBKinase1_024721 Cc1c(Br)c(nn1CC(=O)Nc2ccc(C#N)cc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K14 compound treatment 2706578.0 -807000.0 -0.68 3382283.0 -140000.0 -0.11 -0.5604 -0.8121 3634512 CBKinase1_024722 FC(F)(F)c1cc(nc(OCC(=O)Nc2ccc(Cl)cc2Cl)n1)c3cccs3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K15 mock treatment 3436515.0 -77400.0 -0.07 3486624.0 -35600.0 -0.03 -0.0663 -0.9304 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K16 mock treatment 4571108.0 1060000.0 0.89 4597720.0 1080000.0 0.86 1.2367 0.9998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K17 compound treatment 3767722.0 254000.0 0.21 3008202.0 -514000.0 -0.41 -0.1384 -0.2993 3634513 CBKinase1_024723 COCCCNCCn1cnc2c(N)ncnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K18 compound treatment 3077580.0 -436000.0 -0.37 3242159.0 -280000.0 -0.22 -0.4181 -0.9713 3634514 CBKinase1_024724 Cc1cc(Br)ccc1NC(=O)Cn2ccc(n2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K19 compound treatment 4056994.0 543000.0 0.46 3337407.0 -185000.0 -0.15 0.2197 0.4566 3634515 CBKinase1_024725 COc1ccc(CNc2nc(SC)n[nH]2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K20 compound treatment 3573675.0 59700.0 0.05 3342333.0 -180000.0 -0.14 -0.0658 -0.4327 3634516 CBKinase1_024726 CCN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccc(F)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K21 compound treatment 3551597.0 37700.0 0.03 3647077.0 125000.0 0.1 0.0928 0.8886 3634517 CBKinase1_024727 Clc1ccc2nc(SCCC(=O)Nc3ccccc3C#N)nc(c4ccccc4)c2c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K22 compound treatment 3138079.0 -376000.0 -0.32 3186471.0 -336000.0 -0.27 -0.4134 -0.9964 3634518 CBKinase1_024728 CS(=O)(=O)N1CCN(CC1)c2ccccc2NC(=O)c3ccco3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K23 mock treatment 3046451.0 -467000.0 -0.39 3526844.0 4600.0 0.0 -0.2762 -0.7005 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 K24 mock treatment 3083835.0 -430000.0 -0.36 3004853.0 -517000.0 -0.41 -0.5481 -0.998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L01 compound treatment 2872787.0 -641000.0 -0.54 2660832.0 -861000.0 -0.69 -0.8679 -0.993 3634519 CBKinase1_024729 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)S(=O)(=O)c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L02 mock treatment 2959246.0 -555000.0 -0.47 3234323.0 -288000.0 -0.23 -0.4931 -0.9462 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L03 compound treatment 3538926.0 25000.0 0.02 4270085.0 748000.0 0.6 0.4364 0.7316 3634520 CBKinase1_024730 FC(F)(F)c1cc(nc2cc(nn12)C(=O)Nc3sc4CCCc4c3C#N)c5ccco5 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L04 mock treatment 3448488.0 -65500.0 -0.06 3694265.0 172000.0 0.14 0.0579 0.3918 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L05 compound treatment 3757562.0 244000.0 0.21 3780983.0 259000.0 0.21 0.2911 1.0 3634521 CBKinase1_024731 CC(C(=O)NCC1CCCO1)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L06 mock treatment 3684401.0 170000.0 0.14 3842586.0 320000.0 0.26 0.2822 0.9631 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L07 mock treatment 3705764.0 192000.0 0.16 3874126.0 352000.0 0.28 0.3127 0.9658 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L08 mock treatment 3539120.0 25200.0 0.02 4181620.0 659000.0 0.53 0.3866 0.7351 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L09 compound treatment 3726402.0 212000.0 0.18 3242927.0 -279000.0 -0.22 -0.0307 -0.1074 3634522 CBKinase1_024732 CC(C(=O)NCc1ccco1)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L10 mock treatment 3056963.0 -457000.0 -0.39 3014544.0 -508000.0 -0.4 -0.5587 -0.9997 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L11 compound treatment 3228527.0 -285000.0 -0.24 3507664.0 -14600.0 -0.01 -0.1785 -0.7404 3634523 CBKinase1_024733 CCOC(=O)c1c(NC(=O)CSc2nnc(C)s2)sc3CN(C)CCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L12 mock treatment 3928800.0 415000.0 0.35 3485606.0 -36600.0 -0.03 0.2268 0.6458 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L13 compound treatment 3608914.0 95000.0 0.08 3299529.0 -223000.0 -0.18 -0.0689 -0.3537 3634524 CBKinase1_024734 CC(C(=O)n1nc(C)cc1C)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L14 mock treatment 3165148.0 -349000.0 -0.29 3486544.0 -35700.0 -0.03 -0.2282 -0.7719 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L15 mock treatment 3428925.0 -85000.0 -0.07 3486614.0 -35600.0 -0.03 -0.0708 -0.9178 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L16 mock treatment 4147724.0 634000.0 0.53 5165253.0 1640000.0 1.31 1.304 0.9219 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L17 compound treatment 2262832.0 -1250000.0 -1.06 2359531.0 -1160000.0 -0.93 -1.4015 -0.9979 3634525 CBKinase1_024735 COc1ccc(cc1OC)c2nnc(SCCCN3C(=O)c4cccc5cccc(C3=O)c45)n2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L18 mock treatment 3347137.0 -167000.0 -0.14 3732909.0 211000.0 0.17 0.0192 0.0878 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L19 compound treatment 3343814.0 -170000.0 -0.14 3526634.0 4390.0 0.0 -0.099 -0.6897 3634526 CBKinase1_024736 CCSc1ncc(Cl)c(n1)C(=O)Nc2nnc(SCC=C)s2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L20 mock treatment 3317643.0 -196000.0 -0.17 3178800.0 -343000.0 -0.27 -0.3106 -0.971 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L21 compound treatment 3072019.0 -442000.0 -0.37 3969377.0 447000.0 0.36 -0.0116 -0.0225 1272522 CBKinase1_024737 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4)c(C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L22 mock treatment 4192948.0 679000.0 0.57 4218575.0 696000.0 0.56 0.7974 0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L23 mock treatment 2940499.0 -573000.0 -0.48 4018036.0 496000.0 0.4 -0.0626 -0.1002 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 L24 mock treatment 2998221.0 -516000.0 -0.44 3483099.0 -39100.0 -0.03 -0.3297 -0.7559 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M01 compound treatment 2872587.0 -641000.0 -0.54 2396420.0 -1130000.0 -0.9 -1.017 -0.9707 3634527 CBKinase1_024738 OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccco3)n2c4cccc5ccccc45)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M02 compound treatment 2295200.0 -1220000.0 -1.03 2568907.0 -953000.0 -0.76 -1.2642 -0.9889 3634528 CBKinase1_024739 Cc1cc(C)cc(c1)c2nc3cc(NC(=O)COc4ccccc4[N+](=O)[O-])ccc3o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M03 compound treatment 2556813.0 -957000.0 -0.81 3201192.0 -321000.0 -0.26 -0.7518 -0.8877 3634529 CBKinase1_024740 OC1(CC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)N(CCc3ccccc3)c4ccc(Cl)cc41 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M04 compound treatment 3325366.0 -189000.0 -0.16 3437974.0 -84300.0 -0.07 -0.16 -0.9265 3634530 CBKinase1_024741 COc1ccc(Cl)c(Cn2c(NCC3CCCO3)nc4n(C)c(=O)n(C)c(=O)c24)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M05 compound treatment 4230736.0 717000.0 0.6 3605126.0 82900.0 0.07 0.4742 0.7797 3634531 CBKinase1_024742 FC(F)c1cc(nc2c(cnn12)C(=O)NCc3cccnc3)C4CC4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M06 compound treatment 2574661.0 -939000.0 -0.79 2299623.0 -1220000.0 -0.97 -1.2493 -0.9947 3634532 CBKinase1_024743 CC(C(=O)Nc1cc(ccc1Cl)C(F)(F)F)n2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M07 compound treatment 3615978.0 102000.0 0.09 3169210.0 -353000.0 -0.28 -0.1381 -0.4694 1975921 CBKinase1_024744 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)NCCCN4CCOCC4)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M08 compound treatment 3437338.0 -76600.0 -0.06 3827460.0 305000.0 0.24 0.1263 0.5019 3634533 CBKinase1_024745 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3nn(nc3c2)c4ccc(F)cc4 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M09 mock treatment 3762884.0 249000.0 0.21 3987137.0 465000.0 0.37 0.4105 0.9638 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M10 mock treatment 3465359.0 -48600.0 -0.04 4005836.0 484000.0 0.39 0.2436 0.6284 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M11 compound treatment 3956892.0 443000.0 0.37 3598733.0 76500.0 0.06 0.3073 0.8117 3634534 CBKinase1_024746 CC(C(=O)Nc1ccccc1C(F)(F)F)n2nc([N+](=O)[O-])c(Br)c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M12 compound treatment 3857954.0 344000.0 0.29 3192312.0 -330000.0 -0.26 0.0192 0.0491 3634535 CBKinase1_024747 CCN(CC(=O)Nc1ccccc1)S(=O)(=O)c2ccc(OC)cc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M13 mock treatment 3994118.0 480000.0 0.41 4263752.0 742000.0 0.59 0.7043 0.983 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M14 mock treatment 4127837.0 614000.0 0.52 4307747.0 785000.0 0.63 0.8089 0.9956 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M15 compound treatment 4131330.0 617000.0 0.52 2990333.0 -532000.0 -0.42 0.0684 0.1019 3634536 CBKinase1_024748 CCc1ccccc1NC(=O)Cn2nc(cc2C)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M16 compound treatment 4325641.0 812000.0 0.68 4667330.0 1150000.0 0.91 1.1295 0.99 3634537 CBKinase1_024749 Cc1nn(C)cc1CNC(=O)c2cnn3c(cc(nc23)C4CC4)C(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M17 compound treatment 3535721.0 21800.0 0.02 3548952.0 26700.0 0.02 0.028 0.9973 3634538 CBKinase1_024750 OC(COc1ccc2CCCc2c1)Cn3cnc4ccccc34 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M18 compound treatment 4415906.0 902000.0 0.76 5073856.0 1550000.0 1.24 1.4124 0.9728 3634539 CBKinase1_024751 COC(=O)CCC(=O)NC(=S)Nc1ccccc1F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M19 compound treatment 3913362.0 399000.0 0.34 4752667.0 1230000.0 0.98 0.9317 0.8985 3634540 CBKinase1_024752 COc1ccc(Cl)cc1n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M20 compound treatment 3300248.0 -214000.0 -0.18 4757543.0 1240000.0 0.98 0.5687 0.5682 3634541 CBKinase1_024753 COC(=O)c1ccccc1NC(=O)Cn2nc(c3CCCCCc32)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M21 compound treatment 3755714.0 242000.0 0.2 4372992.0 851000.0 0.68 0.6237 0.8808 3634542 CBKinase1_024754 COc1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M22 compound treatment 3586176.0 72200.0 0.06 3315840.0 -206000.0 -0.16 -0.0732 -0.4175 3634543 CBKinase1_024755 Cc1cc(NC(=O)c2nn3cccnc3c2Cl)no1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M23 compound treatment 3141384.0 -373000.0 -0.31 3930808.0 409000.0 0.33 0.0081 0.0178 3634544 CBKinase1_024756 Cc1c(NC(=O)Cn2ccc(n2)[N+](=O)[O-])c(=O)n(c3ccccc3)n1C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 M24 compound treatment 3334186.0 -180000.0 -0.15 3241316.0 -281000.0 -0.22 -0.2655 -0.982 3634545 CBKinase1_024757 Cn1c(=O)n(C)c2nc(NCc3cccnc3)n(Cc4cccc(c4)C(F)(F)F)c2c1=O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N01 compound treatment 3449949.0 -64000.0 -0.05 2361345.0 -1160000.0 -0.93 -0.6924 -0.7471 3634546 CBKinase1_024758 COC(=O)c1c(NC(=O)Cn2cc(cn2)[N+](=O)[O-])sc3CCCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N02 mock treatment 2742884.0 -771000.0 -0.65 3007708.0 -515000.0 -0.41 -0.7499 -0.9753 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N03 compound treatment 3334105.0 -180000.0 -0.15 3046892.0 -475000.0 -0.38 -0.3752 -0.9193 3634547 CBKinase1_024759 [O-][N+](=O)c1ccn(CC(=O)Nc2sc3CCCc3c2C#N)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N04 mock treatment 4318907.0 805000.0 0.68 3419770.0 -102000.0 -0.08 0.4224 0.6176 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N05 compound treatment 4603367.0 1090000.0 0.92 3329211.0 -193000.0 -0.15 0.541 0.5806 3634548 CBKinase1_024760 COc1ccccc1NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N06 mock treatment 3010193.0 -504000.0 -0.42 3708063.0 186000.0 0.15 -0.1957 -0.435 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N07 compound treatment 3596859.0 82900.0 0.07 4196039.0 674000.0 0.54 0.4292 0.7925 3634549 CBKinase1_024761 [O-][N+](=O)c1ccn(CC(=O)NCc2ccccc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N08 mock treatment 4121866.0 608000.0 0.51 4123892.0 602000.0 0.48 0.7017 0.9994 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N09 mock treatment 4005627.0 492000.0 0.41 4240835.0 719000.0 0.57 0.6983 0.9874 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N10 mock treatment 3964818.0 451000.0 0.38 4200745.0 678000.0 0.54 0.6513 0.9852 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N11 compound treatment 3691930.0 178000.0 0.15 3726824.0 205000.0 0.16 0.2215 0.9991 3634550 CBKinase1_024762 COc1ccc(cc1OC)c2cc(n3ncc(C(=O)NCc4nc5ccccc5[nH]4)c3n2)C(F)(F)F 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N12 mock treatment 4023760.0 510000.0 0.43 3746667.0 224000.0 0.18 0.4306 0.9244 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N13 mock treatment 4055064.0 541000.0 0.46 4270873.0 749000.0 0.6 0.7447 0.9912 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N14 mock treatment 4046218.0 532000.0 0.45 4209493.0 687000.0 0.55 0.7048 0.9951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N15 compound treatment 3773699.0 260000.0 0.22 4179914.0 658000.0 0.52 0.5256 0.9251 3634551 CBKinase1_024763 Cc1nn(CC(=O)Nc2ccc(O)cc2)c(C)c1[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N16 mock treatment 2804033.0 -710000.0 -0.6 3681381.0 159000.0 0.13 -0.3337 -0.5452 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N17 compound treatment 4024016.0 510000.0 0.43 3420690.0 -102000.0 -0.08 0.247 0.5642 3634552 CBKinase1_024764 Cc1nn(C(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)c(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N18 mock treatment 4378643.0 865000.0 0.73 4881593.0 1360000.0 1.08 1.2819 0.9815 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N19 compound treatment 3237706.0 -276000.0 -0.23 4426868.0 905000.0 0.72 0.3451 0.4554 3634553 CBKinase1_024765 COc1cccc(OC)c1C(=O)N(Cc2nc(no2)c3ccc(Cl)cc3)C(C)C 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N20 mock treatment 4083157.0 569000.0 0.48 3609085.0 86800.0 0.07 0.3884 0.8008 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N21 compound treatment 3589220.0 75300.0 0.06 4130158.0 608000.0 0.48 0.3875 0.793 3634554 CBKinase1_024766 COc1ccccc1NC(=O)CNS(=O)(=O)c2ccccc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N22 mock treatment 4196282.0 682000.0 0.58 3889890.0 368000.0 0.29 0.6142 0.951 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N23 compound treatment 3573276.0 59300.0 0.05 4110021.0 588000.0 0.47 0.3667 0.7782 3634555 CBKinase1_024767 NC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccccc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 N24 mock treatment 3421035.0 -92900.0 -0.08 3367703.0 -155000.0 -0.12 -0.1425 -0.9762 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O01 compound treatment 3611800.0 97900.0 0.08 3171158.0 -351000.0 -0.28 -0.1395 -0.4782 3634556 CBKinase1_024768 CC1CCC(CC1C)N(CCCN)Cc2ccco2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O02 compound treatment 2773951.0 -740000.0 -0.62 3546384.0 24100.0 0.02 -0.4278 -0.685 3634557 CBKinase1_024769 O=C1N(CCCSc2nnc(c3ccncc3)n2c4ccccc4)C(=O)c5cccc6cccc1c56 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O03 compound treatment 3636555.0 123000.0 0.1 3258148.0 -264000.0 -0.21 -0.0757 -0.3228 3634558 CBKinase1_024770 COc1ccc(CNc2cc(ccc2C)c3nn4c(C)nnc4s3)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O04 compound treatment 3135898.0 -378000.0 -0.32 2854904.0 -667000.0 -0.53 -0.6016 -0.9701 3634559 CBKinase1_024771 FC(F)S(=O)(=O)c1cccc(NC(=S)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O05 compound treatment 3044650.0 -469000.0 -0.4 2016286.0 -1510000.0 -1.2 -1.1287 -0.893 3634560 CBKinase1_024772 CN(C)CCCNc1ncnc2c1sc3nc(N4CCOCC4)c5CCCc5c32 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O06 compound treatment 4066382.0 552000.0 0.47 4188549.0 666000.0 0.53 0.705 0.9979 3634561 CBKinase1_024773 CCOC(=O)c1c(NC(=O)Cn2cc(cn2)[N+](=O)[O-])sc3CCCc13 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O07 compound treatment 4177379.0 663000.0 0.56 4936534.0 1410000.0 1.13 1.1928 0.9478 3634562 CBKinase1_024774 COc1cc(NC(=O)COc2cccc(C)c2C)ccc1NC(=O)c3ccccc3Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O08 compound treatment 3930623.0 417000.0 0.35 4194479.0 672000.0 0.54 0.6274 0.9791 3634563 CBKinase1_024775 Cc1c(Br)c(nn1CC(=O)NCc2ccccc2)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O09 compound treatment 4071317.0 557000.0 0.47 3977786.0 456000.0 0.36 0.5892 0.9918 3634564 CBKinase1_024776 Cc1nn(C(=O)Cn2cc(cn2)[N+](=O)[O-])c(C)c1Cl 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O10 compound treatment 3699071.0 185000.0 0.16 4030515.0 508000.0 0.41 0.3969 0.9141 3634565 CBKinase1_024777 CCc1c(C)nc(SCC(=O)Nc2ccc(Cl)cc2)nc1O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O11 mock treatment 4344822.0 831000.0 0.7 3872729.0 350000.0 0.28 0.6931 0.9187 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O12 mock treatment 4787193.0 1270000.0 1.07 4353663.0 831000.0 0.66 1.228 0.9731 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O13 compound treatment 3868435.0 354000.0 0.3 3934357.0 412000.0 0.33 0.4437 0.9989 3634566 CBKinase1_024778 Cc1c(Br)c(nn1CC(=O)Nc2cc(F)ccc2F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O14 compound treatment 4659084.0 1150000.0 0.97 4453557.0 931000.0 0.74 1.2079 0.9915 3634567 CBKinase1_024779 COC(=O)c1ccc(Cl)c(NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O15 compound treatment 4894193.0 1380000.0 1.16 4795710.0 1270000.0 1.02 1.541 0.9977 3634568 CBKinase1_024780 Cc1nn(C)c(c1Br)c2nnc(S)n2c3ccc(CC(=O)O)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O16 compound treatment 4992113.0 1480000.0 1.25 4836367.0 1310000.0 1.05 1.6223 0.9962 3634569 CBKinase1_024781 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)COc3ccccc3Cl)sc2C1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O17 compound treatment 5892209.0 2380000.0 2.01 4768256.0 1250000.0 0.99 2.1207 0.9474 3634570 CBKinase1_024782 COC(=O)c1cccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(C)cc3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O18 compound treatment 5408423.0 1890000.0 1.6 3551573.0 29300.0 0.02 1.1465 0.7174 3634571 CBKinase1_024783 COc1ccc(cc1NC(=O)COc2ccc(cc2)C(C)C)c3nc4ccccc4o3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O19 compound treatment 5645892.0 2130000.0 1.8 5492290.0 1970000.0 1.57 2.3819 0.9977 3634572 CBKinase1_024784 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3ccccc3)o2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O20 compound treatment 3584320.0 70400.0 0.06 4962812.0 1440000.0 1.15 0.8539 0.7427 1789193 CBKinase1_024785 CCC(Sc1nnc(N)s1)C(=O)Nc2sc3CCCCc3c2C#N 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O21 compound treatment 4798888.0 1280000.0 1.08 4377824.0 856000.0 0.68 1.2486 0.9751 3634573 CBKinase1_024786 C(CN1CCOCC1)Nc2nc3ccccc3[nH]2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O22 compound treatment 4570141.0 1060000.0 0.89 4456318.0 934000.0 0.74 1.1564 0.996 3634574 CBKinase1_024787 [O-][N+](=O)c1ccn(CC(=O)Nc2cccnc2)n1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O23 compound treatment 4345309.0 831000.0 0.7 4049848.0 528000.0 0.42 0.7932 0.9701 1788838 CBKinase1_024788 COc1ccc(CCNC(=O)c2nc3ncccn3n2)cc1OC 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 O24 compound treatment 3307817.0 -206000.0 -0.17 3219499.0 -303000.0 -0.24 -0.2936 -0.9871 3634575 CBKinase1_024789 CCN1CCN(CC1)c2c(Cl)cccc2NC(=O)COc3ccc(OC)cc3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P01 compound treatment 2654018.0 -860000.0 -0.73 2318258.0 -1200000.0 -0.96 -1.1915 -0.9905 3634576 CBKinase1_024790 CC(=O)c1cccc(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P02 mock treatment 3043384.0 -471000.0 -0.4 2700985.0 -821000.0 -0.65 -0.7435 -0.9713 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P03 compound treatment 3138720.0 -375000.0 -0.32 4118808.0 597000.0 0.48 0.1124 0.1968 3634577 CBKinase1_024791 COc1cccc(CNCCSc2nnnn2C)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P04 mock treatment 3009235.0 -505000.0 -0.43 2939737.0 -583000.0 -0.46 -0.6293 -0.9991 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P05 compound treatment 2428738.0 -1090000.0 -0.92 3241629.0 -281000.0 -0.22 -0.8054 -0.8547 3634578 CBKinase1_024792 CCOC(=O)c1c(NC(=O)c2nc3ncccn3n2)sc4CCCCc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P06 mock treatment 3518006.0 4060.0 0.0 3338896.0 -183000.0 -0.15 -0.1009 -0.6903 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P07 compound treatment 2809010.0 -705000.0 -0.59 3769954.0 248000.0 0.2 -0.2808 -0.4483 3634579 CBKinase1_024793 Cc1cc(nn1CC(=O)Nc2cc(F)ccc2F)[N+](=O)[O-] 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P08 mock treatment 3012247.0 -502000.0 -0.42 3745222.0 223000.0 0.18 -0.1736 -0.3782 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P09 compound treatment 3121148.0 -393000.0 -0.33 3202280.0 -320000.0 -0.26 -0.4146 -0.9916 3634580 CBKinase1_024794 COC(=O)c1cccc(NC(=O)CSc2nnc(o2)c3cc(OC)cc(OC)c3)c1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P10 mock treatment 2044709.0 -1470000.0 -1.24 2106342.0 -1420000.0 -1.13 -1.6743 -0.9989 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P11 mock treatment 3594161.0 80200.0 0.07 3190665.0 -332000.0 -0.26 -0.139 -0.5096 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P12 mock treatment 3711717.0 198000.0 0.17 3834359.0 312000.0 0.25 0.2939 0.9811 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P13 compound treatment 3746837.0 233000.0 0.2 3878042.0 356000.0 0.28 0.3394 0.9839 3634581 CBKinase1_024795 CCOc1ccc(NC(=O)C(C)n2nc(C)c([N+](=O)[O-])c2C)cc1 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P14 mock treatment 4113919.0 600000.0 0.51 3891140.0 369000.0 0.29 0.5658 0.9666 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P15 compound treatment 4120509.0 607000.0 0.51 4524888.0 1000000.0 0.8 0.9269 0.9768 3634582 CBKinase1_024796 OC(=O)Cc1ccc(cc1)n2c(S)nnc2c3ccc4ccccc4n3 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P16 mock treatment 4294691.0 781000.0 0.66 4249859.0 728000.0 0.58 0.8757 0.998 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P17 compound treatment 4161741.0 648000.0 0.55 4126428.0 604000.0 0.48 0.7269 0.998 3634583 CBKinase1_024797 Cn1c(SCCC(=O)O)nnc1c2ccncc2 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P18 mock treatment 4245216.0 731000.0 0.62 4715729.0 1190000.0 0.95 1.1088 0.978 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P19 compound treatment 4570705.0 1060000.0 0.89 4114831.0 593000.0 0.47 0.9643 0.9559 1787257 CBKinase1_024798 Cn1c(=O)[nH]c(=O)c2n(CCN3CCOCC3)cnc12 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P20 mock treatment 4311973.0 798000.0 0.67 4344010.0 822000.0 0.65 0.9391 0.9999 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P21 compound treatment 4585772.0 1070000.0 0.9 4495010.0 973000.0 0.78 1.1875 0.9971 3634584 CBKinase1_024799 OCc1cc(Cl)ccc1OCC(=O)O 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P22 mock treatment 4076040.0 562000.0 0.47 3901351.0 379000.0 0.3 0.5489 0.9763 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P23 compound treatment 3851866.0 338000.0 0.29 3750321.0 228000.0 0.18 0.3301 0.9764 3634585 CBKinase1_024800 NC(=O)CN1C(=O)C(O)(C2CCc3ccccc3C2=O)c4ccccc14 1010.0096 DAPIStaining(1010.0096) PlasmodiumViabilityAssay 1010.0096.2401 P24 mock treatment 3330863.0 -183000.0 -0.15 3210948.0 -311000.0 -0.25 -0.2846 -0.974