ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A01 compound treatment 2032380.0 -259000.0 -0.28 2308380.0 -186000.0 -0.17 1724640.0 -154406.39351852 -0.151278573751584 -0.3448 -0.9645 3178890 Maybridge4_004577 CC(C)(C)c1ccc(SC(=O)c2ccc(OCC(F)(F)F)nc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A02 compound treatment 2059636.0 -232000.0 -0.25 2165770.0 -329000.0 -0.3 1739988.0 -139058.39351852 -0.136241479127255 -0.3949 -0.9575 1333720 Maybridge4_004578 COc1ccc(OCc2ncc(s2)c3ccc4OCCCOc4c3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A03 compound treatment 2043747.0 -248000.0 -0.26 2121979.0 -373000.0 -0.34 1695204.0 -183842.39351852 -0.180118286897384 -0.4531 -0.9697 1593366 Maybridge4_004579 Cc1nn(c(N)c1c2nc(cs2)c3ccccc3)c4cc(Cl)ccc4Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A04 compound treatment 2340195.0 48700.0 0.05 2586468.0 91900.0 0.08 2063257.0 184210.60648148 0.18047904094781 0.1827 0.8878 3178891 Maybridge4_004580 Cc1ccc(cc1F)c2nc(cs2)c3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A05 compound treatment 2233329.0 -58200.0 -0.06 2581169.0 86600.0 0.08 2115616.0 236569.60648148 0.231777401479164 0.1439 0.5697 3065742 Maybridge4_004581 FC(F)(F)Oc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCC(CC3)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A06 compound treatment 2431873.0 140000.0 0.15 2696641.0 202000.0 0.19 1920531.0 41484.6064814799 0.0406442502681165 0.2165 0.8975 3178892 Maybridge4_004582 Cc1c(C#N)c(SCc2cccc(c2)C(F)(F)F)nc3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A07 compound treatment 2225521.0 -66000.0 -0.07 2426121.0 -68500.0 -0.06 1924426.0 45379.6064814799 0.0444603490146476 -0.051 -0.4905 3178893 Maybridge4_004583 CCOC(=O)c1cc(C#N)c(Sc2ccc(C)cc2)nc1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A08 compound treatment 2305098.0 13600.0 0.01 2431773.0 -62800.0 -0.06 1896220.0 17173.6064814799 0.0168257196835417 -0.0152 -0.246 3065743 Maybridge4_004584 Cn1nc(c2cccc(c2)C3OCCO3)c(=O)n(C)c1=S 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A09 compound treatment 2307890.0 16400.0 0.02 2730773.0 236000.0 0.22 2126710.0 247663.60648148 0.242646669641941 0.2751 0.8449 3178894 Maybridge4_004585 Cc1nc(cs1)C(=N)NC(=O)c2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A10 compound treatment 2687436.0 396000.0 0.42 2924011.0 429000.0 0.39 2279599.0 400552.60648148 0.392438587808411 0.6967 0.9995 3065744 Maybridge4_004586 CC1=N/C(=C\c2sccc2C)/C(=O)O1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A11 compound treatment 2571692.0 280000.0 0.3 2897082.0 402000.0 0.37 2050871.0 171824.60648148 0.168343944908134 0.4821 0.9583 1220314 Maybridge4_004587 Cc1cc(C)n(Cc2ccccc2)c(=O)c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A12 compound treatment 2419610.0 128000.0 0.14 2830807.0 336000.0 0.31 1920587.0 41540.6064814799 0.0406991158726879 0.28 0.8252 3178895 Maybridge4_004588 Cc1ccccc1c2nnc(o2)c3cc(nn3Cc4ccc(F)cc4)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A13 compound treatment 2474679.0 183000.0 0.19 2229178.0 -265000.0 -0.24 1969505.0 90458.6064814799 0.0886261809517151 0.0231 0.0714 3178896 Maybridge4_004589 FC(F)(F)COc1ccc(cn1)c2nnc(SCc3ccccc3C(F)(F)F)o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A14 compound treatment 2038195.0 -253000.0 -0.27 2453087.0 -41500.0 -0.04 1765001.0 -114045.39351852 -0.11173516899966 -0.2419 -0.823 3065746 Maybridge4_004590 CN(C)/C=C/C(=O)C1(CC2CC3CC(C2)C1)C3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A15 compound treatment 2154090.0 -137000.0 -0.15 2410624.0 -84000.0 -0.08 1651346.0 -227700.39351852 -0.223087852706206 -0.2575 -0.928 3178897 Maybridge4_004591 CCOC(=O)c1cc(C#N)c(nc1C(F)(F)F)N2CCN(CC2)C(=O)c3snnc3C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A16 compound treatment 2106211.0 -185000.0 -0.2 2567398.0 72800.0 0.07 1748201.0 -130845.39351852 -0.128194850371091 -0.1492 -0.6108 3065747 Maybridge4_004592 CC1CCCCN1C(=S)Nc2cccc(C)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A17 compound treatment 1988258.0 -303000.0 -0.32 2152997.0 -342000.0 -0.31 1647899.0 -231147.39351852 -0.226465026616166 -0.4975 -0.9889 3178898 Maybridge4_004593 FC(F)(F)c1ccc(nc1)c2nnc(c3ccccn3)c(n2)c4ccccn4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A18 compound treatment 1868853.0 -423000.0 -0.45 2134080.0 -361000.0 -0.33 1601997.0 -277049.39351852 -0.271437186991846 -0.6068 -0.9785 3065748 Maybridge4_004594 CC(C)n1c(=S)[nH]c2cc(ccc12)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A19 compound treatment 1946273.0 -345000.0 -0.37 1928460.0 -566000.0 -0.52 1455042.0 -424004.39351852 -0.415415310559621 -0.7512 -0.9895 3178899 Maybridge4_004595 COc1ccc(OCC(=N)NC(=S)Nc2ccc(Cl)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A20 compound treatment 1824228.0 -467000.0 -0.5 1688984.0 -806000.0 -0.74 1320312.0 -558734.39351852 -0.547416076700864 -1.029 -0.985 3065749 Maybridge4_004596 Clc1ccc(NC(=C(C#N)C#N)NC(=O)c2ccccc2Cl)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A21 compound treatment 1578416.0 -713000.0 -0.76 1783745.0 -711000.0 -0.65 1232646.0 -646400.39351852 -0.63330622117157 -1.1793 -0.9968 3178900 Maybridge4_004597 FC(F)(F)c1cc(nc(Sc2ccccc2NC(=O)c3cccs3)c1C#N)c4cccs4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A22 mock treatment 1242919.0 -1050000.0 -1.11 1642321.0 -852000.0 -0.78 1106947.0 -772099.39351852 -0.756458928832731 -1.531 -0.9834 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A23 mock treatment 1331310.0 -960000.0 -1.02 1386066.0 -1110000.0 -1.02 1318614.0 -560432.39351852 -0.549079680210905 -1.4926 -0.9686 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 A24 mock treatment 1149413.0 -1140000.0 -1.21 1349700.0 -1140000.0 -1.05 1182341.0 -696705.39351852 -0.682592189706679 -1.7006 -0.9754 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B01 mock treatment 2380724.0 89200.0 0.09 2505492.0 10900.0 0.01 1902785.0 23738.6064814799 0.0232577320766038 0.0739 0.7533 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B02 mock treatment 2470519.0 179000.0 0.19 2634371.0 140000.0 0.13 2123900.0 244853.60648148 0.239893591983981 0.3223 0.9711 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B03 mock treatment 2476558.0 185000.0 0.2 2932026.0 437000.0 0.4 2193515.0 314468.60648148 0.308098396666848 0.5229 0.9638 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B04 mock treatment 2625540.0 334000.0 0.35 2730377.0 236000.0 0.22 2147385.0 268338.60648148 0.262902854901127 0.4815 0.9791 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B05 mock treatment 2748735.0 457000.0 0.49 2799947.0 305000.0 0.28 2332941.0 453894.60648148 0.444700035648582 0.6988 0.9765 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B06 mock treatment 2768086.0 477000.0 0.51 2866703.0 372000.0 0.34 2413249.0 534202.60648148 0.523381231575776 0.7915 0.9842 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B07 mock treatment 2731144.0 440000.0 0.47 3198499.0 704000.0 0.65 2294210.0 415163.60648148 0.406753611886862 0.877 0.9806 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B08 mock treatment 2623512.0 332000.0 0.35 3147387.0 653000.0 0.6 2280804.0 401757.60648148 0.393619178049636 0.7763 0.9725 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B09 mock treatment 2580323.0 289000.0 0.31 2930620.0 436000.0 0.4 2326095.0 447048.60648148 0.437992715489724 0.6608 0.9898 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B10 mock treatment 2763018.0 472000.0 0.5 2945130.0 451000.0 0.41 2203453.0 324406.60648148 0.3178350819924 0.7112 0.9838 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B11 mock treatment 2763679.0 472000.0 0.5 3064176.0 570000.0 0.52 2115251.0 236204.60648148 0.231419795306511 0.7247 0.9534 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B12 mock treatment 2555058.0 264000.0 0.28 2920249.0 426000.0 0.39 2055999.0 176952.60648148 0.173368066698176 0.487 0.9539 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B13 mock treatment 2696574.0 405000.0 0.43 2818097.0 323000.0 0.3 2326410.0 447363.60648148 0.438301334515438 0.6727 0.9862 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B14 mock treatment 2436661.0 145000.0 0.15 2684967.0 190000.0 0.17 2038565.0 159518.60648148 0.156287228303561 0.28 0.9984 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B15 mock treatment 2495402.0 204000.0 0.22 3072383.0 578000.0 0.53 1930903.0 51856.6064814799 0.0508061440290975 0.4601 0.8011 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B16 mock treatment 2174065.0 -117000.0 -0.12 2641539.0 147000.0 0.13 2110922.0 231875.60648148 0.227178488124551 0.1369 0.4686 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B17 mock treatment 2178617.0 -113000.0 -0.12 2439918.0 -54700.0 -0.05 1947411.0 68364.6064814799 0.0669797404624059 -0.0595 -0.407 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B18 mock treatment 2377722.0 86200.0 0.09 2326519.0 -168000.0 -0.15 1763022.0 -116024.39351852 -0.113674080275497 -0.1017 -0.479 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B19 mock treatment 2109229.0 -182000.0 -0.19 2352666.0 -142000.0 -0.13 1786562.0 -92484.3935185201 -0.0906109314967184 -0.2392 -0.9559 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B20 mock treatment 2050828.0 -241000.0 -0.26 1731977.0 -763000.0 -0.7 1369301.0 -509745.39351852 -0.499419449873184 -0.8395 -0.9367 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B21 mock treatment 2256800.0 -34700.0 -0.04 1761634.0 -733000.0 -0.67 1457217.0 -421829.39351852 -0.413284369667784 -0.6477 -0.8204 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B22 mock treatment 1990857.0 -301000.0 -0.32 1486312.0 -1010000.0 -0.92 1146320.0 -732726.39351852 -0.717883510104317 -1.1324 -0.9336 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B23 mock treatment 1347927.0 -944000.0 -1.0 1345625.0 -1150000.0 -1.05 1042053.0 -836993.39351852 -0.820038367101638 -1.6603 -0.9946 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 B24 mock treatment 1144829.0 -1150000.0 -1.22 1313674.0 -1180000.0 -1.08 1092655.0 -786391.39351852 -0.770461414913712 -1.7732 -0.9836 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C01 compound treatment 2239665.0 -51800.0 -0.06 2407764.0 -86900.0 -0.08 1839672.0 -39374.3935185201 -0.0385767840183437 -0.1 -0.96 3065750 Maybridge4_004598 FC(F)(F)c1cccc(NC(=O)CCn2cccc(c2=O)C(F)(F)F)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C02 compound treatment 1696154.0 -595000.0 -0.63 1901202.0 -593000.0 -0.54 1383506.0 -495540.39351852 -0.485502201427876 -0.9595 -0.9941 3178901 Maybridge4_004599 Oc1ccc2c(CSc3ccc(Cl)cc3)cc(=O)oc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C03 compound treatment 2627439.0 336000.0 0.36 2712228.0 218000.0 0.2 2014099.0 135052.60648148 0.132316837563476 0.3977 0.9252 3178902 Maybridge4_004600 CN(CCOC(=O)c1snnc1C)c2ccc(C#N)cn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C04 compound treatment 2442315.0 151000.0 0.16 2734778.0 240000.0 0.22 1736313.0 -142733.39351852 -0.139842034427256 0.1389 0.4537 1339676 Maybridge4_004601 Cn1nc(cc1C(=O)Nc2cccnc2)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C05 compound treatment 2177672.0 -114000.0 -0.12 1953422.0 -541000.0 -0.5 1685494.0 -193552.39351852 -0.189631590832896 -0.4657 -0.8551 3065771 Maybridge4_004602 CCCNC(=O)Nc1ccc(nc1)N2CCC(CC2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C06 compound treatment 2389256.0 97800.0 0.1 2788139.0 294000.0 0.27 2176576.0 297529.60648148 0.291502531026927 0.3836 0.9355 1741890 Maybridge4_004603 Cc1cc(C(=O)Nc2ccc(C)cc2)n(Cc3ccc(C)cc3)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C07 compound treatment 2425811.0 134000.0 0.14 2652269.0 158000.0 0.14 2127587.0 248540.60648148 0.243505904199247 0.3064 0.9663 3065772 Maybridge4_004604 CCOC(=O)c1cc(C#N)c(Nc2ccccc2OC)nc1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C08 compound treatment 2288761.0 -2720.0 0.0 2509097.0 14500.0 0.01 1835766.0 -43280.3935185201 -0.0424036599372014 -0.0185 -0.4153 3065773 Maybridge4_004605 N#Cc1ccc(nc1)N2CCCNCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C09 compound treatment 2275899.0 -15600.0 -0.02 2620423.0 126000.0 0.12 1839031.0 -40015.3935185201 -0.0392047992420989 0.0344 0.2796 3065774 Maybridge4_004606 Cc1nc(cs1)C(=N)NC(=O)c2ccc(OC(F)(F)F)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C10 compound treatment 2389586.0 98100.0 0.1 2982231.0 488000.0 0.45 2021793.0 142746.60648148 0.139854979734416 0.3989 0.8316 3065775 Maybridge4_004607 N[C@@H](Cc1ccc(OC(F)(F)F)cc1)C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C11 compound treatment 2575737.0 284000.0 0.3 2953956.0 459000.0 0.42 2101025.0 221978.60648148 0.217481972259488 0.543 0.9663 3065776 Maybridge4_004608 Cn1c(SCC(=O)Nc2cccc(Cl)c2)nnc1c3ccc(OCC(F)(F)F)nc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C12 compound treatment 2193682.0 -97800.0 -0.1 2407041.0 -87600.0 -0.08 1813653.0 -65393.3935185201 -0.0640687155423473 -0.1433 -0.981 3065777 Maybridge4_004609 Cc1cc(nn1C(C)(C)C)C(=O)Nc2ccc(C)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C13 compound treatment 1845681.0 -446000.0 -0.47 1997843.0 -497000.0 -0.46 1427980.0 -451066.39351852 -0.441929113968768 -0.7915 -0.9996 3178903 Maybridge4_004610 CSc1nnc(c2cc(OCC(F)(F)F)nc(OCC(F)(F)F)c2)n1Cc3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C14 compound treatment 2346243.0 54800.0 0.06 2531107.0 36500.0 0.03 1972872.0 93825.6064814799 0.0919249754265727 0.106 0.9311 3065778 Maybridge4_004611 Fc1ccc(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c(Cl)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C15 compound treatment 2010881.0 -281000.0 -0.3 2326667.0 -168000.0 -0.15 1877309.0 -1737.39351852005 -0.0017021990316446 -0.262 -0.7808 3178904 Maybridge4_004612 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)Nc3cccc(Cl)c3)o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C16 compound treatment 2100856.0 -191000.0 -0.2 2119656.0 -375000.0 -0.34 1861432.0 -17614.3935185201 -0.0172575776705856 -0.3253 -0.8148 3065781 Maybridge4_004613 Cc1cccc(NC(=S)N2CCCCC2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C17 compound treatment 1900043.0 -391000.0 -0.42 2466735.0 -27900.0 -0.03 1510294.0 -368752.39351852 -0.361282553706389 -0.4635 -0.8404 3178905 Maybridge4_004614 Fc1cccc(c1)C(=O)CSC2=NNC(S2)c3ccccn3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C18 compound treatment 1703765.0 -588000.0 -0.62 2166896.0 -328000.0 -0.3 1402665.0 -476381.39351852 -0.466731306463873 -0.8035 -0.9616 3065782 Maybridge4_004615 Cn1c(SCC=C)ncc1c2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C19 compound treatment 1926213.0 -365000.0 -0.39 2000019.0 -495000.0 -0.45 1378330.0 -500716.39351852 -0.490573350878979 -0.769 -0.9955 3178906 Maybridge4_004616 Cc1ccc(NC(=S)NC(=N)COc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C20 compound treatment 1479194.0 -812000.0 -0.86 1851368.0 -643000.0 -0.59 1440472.0 -438574.39351852 -0.429690165177583 -1.0868 -0.9616 3065783 Maybridge4_004617 Sc1nnc(SCC2CC2)s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C21 compound treatment 1588835.0 -703000.0 -0.75 1436951.0 -1060000.0 -0.97 1310406.0 -568640.39351852 -0.557121410252376 -1.3124 -0.9762 1187470 Maybridge4_004618 NC(=S)c1ccc(nc1)n2cncn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C22 mock treatment 1467379.0 -824000.0 -0.88 1390267.0 -1100000.0 -1.01 1149283.0 -729763.39351852 -0.714980531776725 -1.5027 -0.9903 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C23 mock treatment 1345434.0 -946000.0 -1.01 1405093.0 -1090000.0 -1.0 1057922.0 -821124.39351852 -0.804490826406207 -1.6214 -0.9951 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 C24 mock treatment 1258594.0 -1030000.0 -1.1 1452394.0 -1040000.0 -0.96 1011561.0 -867485.39351852 -0.849912688790785 -1.6759 -0.9945 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D01 mock treatment 2149563.0 -142000.0 -0.15 2221198.0 -273000.0 -0.25 1713331.0 -165715.39351852 -0.162358486646198 -0.3255 -0.973 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D02 mock treatment 2245105.0 -46400.0 -0.05 2488447.0 -6170.0 -0.01 1816029.0 -63017.3935185201 -0.0617408463198163 -0.0674 -0.8506 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D03 mock treatment 2411430.0 120000.0 0.13 2548833.0 54200.0 0.05 1891389.0 12342.6064814799 0.0120925815463165 0.1093 0.7955 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D04 mock treatment 2428539.0 137000.0 0.15 2661449.0 167000.0 0.15 1950918.0 71871.6064814799 0.0704156989486921 0.213 0.957 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D05 mock treatment 2677390.0 386000.0 0.41 2557542.0 62900.0 0.06 2021412.0 142365.60648148 0.139481697674743 0.3506 0.8023 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D06 mock treatment 2853488.0 562000.0 0.6 2838905.0 344000.0 0.32 2172562.0 293515.60648148 0.287569842870682 0.693 0.944 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D07 mock treatment 2409985.0 119000.0 0.13 2892372.0 398000.0 0.36 2331309.0 452262.60648148 0.4431010951725 0.539 0.9175 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D08 mock treatment 2742912.0 451000.0 0.48 2963597.0 469000.0 0.43 2436459.0 557412.60648148 0.546121065184759 0.8404 0.9952 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D09 mock treatment 2683230.0 392000.0 0.42 2661978.0 167000.0 0.15 2249993.0 370946.60648148 0.363432318363019 0.5387 0.9394 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D10 mock treatment 2564987.0 274000.0 0.29 2945604.0 451000.0 0.41 2248052.0 369005.60648148 0.361530637318856 0.6152 0.9901 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D11 mock treatment 2610173.0 319000.0 0.34 2973537.0 479000.0 0.44 1948218.0 69171.6064814799 0.0677703930139979 0.4881 0.8739 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D12 mock treatment 2898859.0 607000.0 0.65 2690672.0 196000.0 0.18 2106236.0 227189.60648148 0.222587412713448 0.6049 0.8568 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D13 mock treatment 2743216.0 452000.0 0.48 2876147.0 382000.0 0.35 2294416.0 415369.60648148 0.40695543893225 0.714 0.9917 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D14 mock treatment 2530494.0 239000.0 0.25 2665251.0 171000.0 0.16 2042582.0 163535.60648148 0.160222855688623 0.3294 0.973 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D15 mock treatment 2467840.0 176000.0 0.19 2788587.0 294000.0 0.27 2070470.0 191423.60648148 0.187545926765198 0.372 0.9842 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D16 mock treatment 2277277.0 -14200.0 -0.02 2528957.0 34300.0 0.03 2009536.0 130489.60648148 0.127846270533843 0.0833 0.6283 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D17 mock treatment 2029711.0 -262000.0 -0.28 2175956.0 -319000.0 -0.29 1719853.0 -159193.39351852 -0.155968603199503 -0.4193 -0.9696 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D18 mock treatment 2097705.0 -194000.0 -0.21 2029268.0 -465000.0 -0.43 1790736.0 -88310.3935185201 -0.0865214844702688 -0.4151 -0.8622 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D19 mock treatment 1700779.0 -591000.0 -0.63 2054840.0 -440000.0 -0.4 1510141.0 -368905.39351852 -0.361432454376022 -0.8038 -0.9697 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D20 mock treatment 1473344.0 -818000.0 -0.87 1763234.0 -731000.0 -0.67 1220468.0 -658578.39351852 -0.64523753067998 -1.2615 -0.9906 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D21 mock treatment 1578984.0 -713000.0 -0.76 1525955.0 -969000.0 -0.89 1260928.0 -618118.39351852 -0.605597131377118 -1.2993 -0.9884 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D22 mock treatment 1418363.0 -873000.0 -0.93 1424716.0 -1070000.0 -0.98 1342080.0 -536966.39351852 -0.526089032409596 -1.4055 -0.9701 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D23 mock treatment 1479776.0 -812000.0 -0.86 1376414.0 -1120000.0 -1.02 1079282.0 -799764.39351852 -0.783563517233959 -1.542 -0.9937 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 D24 mock treatment 1212794.0 -1080000.0 -1.15 1277998.0 -1220000.0 -1.11 1068072.0 -810974.39351852 -0.794546435577634 -1.7643 -0.988 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E01 compound treatment 2475495.0 184000.0 0.2 2461220.0 -33400.0 -0.03 1798866.0 -80180.3935185201 -0.0785561743780228 0.0499 0.2342 3178907 Maybridge4_004619 FC(F)(F)c1cccn(CCC(=O)Sc2ccccc2)c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E02 compound treatment 2582186.0 291000.0 0.31 2761498.0 267000.0 0.24 2108609.0 229562.60648148 0.224912342707163 0.4494 0.9906 1539590 Maybridge4_004620 Oc1ccc2c(CSc3ccccn3)cc(=O)oc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E03 compound treatment 2551511.0 260000.0 0.28 2596858.0 102000.0 0.09 2075664.0 196617.60648148 0.192634711589199 0.3248 0.9291 3178908 Maybridge4_004621 NC(=S)c1ccc(nc1)N2CCC(CC2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E04 compound treatment 2198123.0 -93400.0 -0.1 2440546.0 -54100.0 -0.05 1835695.0 -43351.3935185201 -0.0424732216858544 -0.1104 -0.9297 3178909 Maybridge4_004622 Cc1cccc(Cl)c1OC(=O)c2cc(nn2C)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E05 compound treatment 2489632.0 198000.0 0.21 2861435.0 367000.0 0.34 2024118.0 145071.60648148 0.14213288206707 0.3977 0.9439 3065784 Maybridge4_004623 OC(=O)CCn1cc(ccc1=O)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E06 compound treatment 2292350.0 865.0 0.0 3073257.0 579000.0 0.53 2202878.0 323831.60648148 0.317271729802604 0.4899 0.7927 1605604 Maybridge4_004624 Cc1cc(C(=O)Sc2ccccc2)n(Cc3ccc(C)cc3)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E07 compound treatment 2445151.0 154000.0 0.16 2738892.0 244000.0 0.22 2347110.0 468063.60648148 0.458582013348094 0.4883 0.9113 3065785 Maybridge4_004625 FC(F)(F)c1cccn(Cc2ccccc2)c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E08 compound treatment 2450449.0 159000.0 0.17 2982933.0 488000.0 0.45 2326466.0 447419.60648148 0.438356200120009 0.609 0.9386 3178983 Maybridge4_004626 O=c1[nH]nc(SCc2ccccc2)n1c3ccc(OCc4ccccc4)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E09 compound treatment 2720770.0 429000.0 0.46 3117774.0 623000.0 0.57 2082474.0 203427.60648148 0.199306761002261 0.7082 0.9347 3065786 Maybridge4_004627 Cn1c(S)nnc1Cn2cc(ccc2=O)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E10 compound treatment 2527794.0 236000.0 0.25 2856823.0 362000.0 0.33 2087002.0 207955.60648148 0.203743037029037 0.4543 0.9802 3178984 Maybridge4_004628 CC(=O)N/C(=C/c1ccc(Cl)c(Cl)c1)/C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E11 compound treatment 2267369.0 -24100.0 -0.03 2564335.0 69700.0 0.06 2074896.0 195849.60648148 0.191882269012219 0.1329 0.6518 3065787 Maybridge4_004629 Cn1c(SCc2ccc(cc2)C(F)(F)F)nnc1c3ccc(OCC(F)(F)F)nc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E12 compound treatment 2394321.0 103000.0 0.11 2910637.0 416000.0 0.38 2170225.0 291178.60648148 0.285280183622763 0.4479 0.9168 3178985 Maybridge4_004630 Clc1ccc(cc1)c2nnc(SCC3CC3)o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E13 compound treatment 2585576.0 294000.0 0.31 2923621.0 429000.0 0.39 2337119.0 458072.60648148 0.448793401646786 0.6665 0.9896 3178986 Maybridge4_004631 Cc1ccccc1NC(=O)c2cccc(Cn3cc(ccc3=O)C(F)(F)F)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E14 compound treatment 2237033.0 -54500.0 -0.06 2746107.0 251000.0 0.23 2201890.0 322843.60648148 0.316303743779094 0.2823 0.7135 1516971 Maybridge4_004632 Cc1ccc(cc1)C(=O)CSc2nnc(o2)c3cc(nn3Cc4cccc(C)c4)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E15 compound treatment 2206544.0 -84900.0 -0.09 2543618.0 49000.0 0.04 2186664.0 307617.60648148 0.301386177793296 0.1478 0.4651 3178987 Maybridge4_004633 NNC(=N)c1ccc(cn1)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E16 compound treatment 2240804.0 -50700.0 -0.05 2484527.0 -10100.0 -0.01 1800765.0 -78281.3935185201 -0.0766956425372878 -0.0807 -0.8571 3065788 Maybridge4_004634 CC(C)N(CCC#N)CN1C(=O)c2ccccc2C1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E17 compound treatment 2509854.0 218000.0 0.23 2667167.0 173000.0 0.16 2183982.0 304935.60648148 0.2987585072315 0.3978 0.9701 3065812 Maybridge4_004635 CC(C)c1ccc(NC(=O)CSC2=NNC(S2)c3ccccn3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E18 compound treatment 1812948.0 -479000.0 -0.51 2110259.0 -384000.0 -0.35 1741844.0 -137202.39351852 -0.134423076232888 -0.5746 -0.9076 3065813 Maybridge4_004636 Clc1ccc(N/C(=N\C#N)/Oc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E19 compound treatment 1799504.0 -492000.0 -0.52 2227704.0 -267000.0 -0.24 1596327.0 -282719.39351852 -0.276992329454704 -0.603 -0.9418 1232015 Maybridge4_004637 Sc1nc2CCCCc2c(c3cccs3)c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E20 compound treatment 1717142.0 -574000.0 -0.61 1592845.0 -902000.0 -0.83 1303090.0 -575956.39351852 -0.564289209592459 -1.1553 -0.9856 3065814 Maybridge4_004638 CC(Sc1ccc(C)cc1)C(=O)c2ccc(C)c(Cl)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E21 compound treatment 1721880.0 -570000.0 -0.61 1519378.0 -975000.0 -0.89 1170408.0 -708638.39351852 -0.694283462195089 -1.2663 -0.9867 3065815 Maybridge4_004639 CCOC(=O)c1nc(C)nc(Sc2nnc([nH]2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E22 mock treatment 1670764.0 -621000.0 -0.66 1480248.0 -1010000.0 -0.93 1099763.0 -779283.39351852 -0.763497402104895 -1.3583 -0.9901 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E23 mock treatment 1453705.0 -838000.0 -0.89 1387632.0 -1110000.0 -1.01 1425052.0 -453994.39351852 -0.444797801293503 -1.3565 -0.9545 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 E24 mock treatment 1266697.0 -1020000.0 -1.09 1792430.0 -702000.0 -0.64 1062491.0 -816555.39351852 -0.800014380918941 -1.4622 -0.9769 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F01 mock treatment 2201490.0 -90000.0 -0.1 2418802.0 -75800.0 -0.07 1816884.0 -62162.3935185201 -0.0609031661071632 -0.1305 -0.9813 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F02 mock treatment 2598846.0 307000.0 0.33 2463082.0 -31500.0 -0.03 1956493.0 77446.6064814799 0.0758777658323663 0.2157 0.6409 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F03 mock treatment 2707705.0 416000.0 0.44 2798293.0 304000.0 0.28 2067716.0 188669.60648148 0.18484771471181 0.5228 0.9431 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F04 mock treatment 2697829.0 406000.0 0.43 2997418.0 503000.0 0.46 2269933.0 390886.60648148 0.382968392562206 0.7364 0.9972 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F05 mock treatment 2716359.0 425000.0 0.45 3026103.0 531000.0 0.49 2136767.0 257720.60648148 0.252499944377208 0.6877 0.9678 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F06 mock treatment 2898621.0 607000.0 0.65 2926173.0 432000.0 0.4 2234929.0 355882.60648148 0.348673470733303 0.8021 0.9627 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F07 mock treatment 2856330.0 565000.0 0.6 3171886.0 677000.0 0.62 2354524.0 475477.60648148 0.465845827496176 0.9739 0.9926 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F08 mock treatment 2637685.0 346000.0 0.37 3086565.0 592000.0 0.54 2467788.0 588741.60648148 0.576815431713661 0.8586 0.9834 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F09 mock treatment 2637363.0 346000.0 0.37 3083396.0 589000.0 0.54 2373461.0 494414.60648148 0.484399219527771 0.8034 0.9883 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F10 mock treatment 2853240.0 562000.0 0.6 3193580.0 699000.0 0.64 2358441.0 479394.60648148 0.469683480587361 0.9857 0.992 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F11 mock treatment 2729962.0 438000.0 0.47 3229326.0 735000.0 0.67 2385127.0 506080.60648148 0.495828900651528 0.944 0.9862 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F12 mock treatment 2880964.0 589000.0 0.63 2854882.0 360000.0 0.33 2375259.0 496212.60648148 0.48616079733169 0.833 0.9698 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F13 mock treatment 2592227.0 301000.0 0.32 2958458.0 464000.0 0.43 2389912.0 510865.60648148 0.500516970613569 0.7189 0.9844 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F14 mock treatment 2406390.0 115000.0 0.12 2922263.0 428000.0 0.39 2378572.0 499525.60648148 0.489406685687853 0.5793 0.9069 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F15 mock treatment 2684428.0 393000.0 0.42 3086940.0 592000.0 0.54 2297146.0 418099.60648148 0.409630137155107 0.791 0.9912 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F16 mock treatment 2724527.0 433000.0 0.46 2598303.0 104000.0 0.1 1906228.0 27181.6064814799 0.0266309870148084 0.3359 0.7138 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F17 mock treatment 2273332.0 -18200.0 -0.02 2401508.0 -93100.0 -0.09 2044845.0 165798.60648148 0.162440013959072 0.0334 0.1809 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F18 mock treatment 2239277.0 -52200.0 -0.06 2396389.0 -98200.0 -0.09 1724719.0 -154327.39351852 -0.151201174059421 -0.1713 -0.9284 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F19 mock treatment 2358259.0 66800.0 0.07 2152866.0 -342000.0 -0.31 1455020.0 -424026.39351852 -0.415436864904274 -0.3797 -0.7231 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F20 mock treatment 2314817.0 23300.0 0.02 1690198.0 -804000.0 -0.74 1390654.0 -488392.39351852 -0.478498998901508 -0.6876 -0.782 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F21 mock treatment 1974744.0 -317000.0 -0.34 1631030.0 -864000.0 -0.79 1178490.0 -700556.39351852 -0.686365179763904 -1.0475 -0.952 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F22 mock treatment 1722327.0 -569000.0 -0.6 1512906.0 -982000.0 -0.9 1421045.0 -458001.39351852 -0.448723631249177 -1.1277 -0.9611 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F23 mock treatment 1368326.0 -923000.0 -0.98 1378255.0 -1120000.0 -1.02 1069237.0 -809809.39351852 -0.79340503505396 -1.6151 -0.9943 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 F24 mock treatment 1411618.0 -880000.0 -0.94 1320850.0 -1170000.0 -1.08 1091330.0 -787716.39351852 -0.77175957430759 -1.6064 -0.9912 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G01 compound treatment 2255189.0 -36300.0 -0.04 2122489.0 -372000.0 -0.34 1674959.0 -204087.39351852 -0.199953182692897 -0.3346 -0.8424 3065816 Maybridge4_004640 Cc1nc(N)nc(CSc2ccccc2)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G02 compound treatment 2513421.0 222000.0 0.24 2601737.0 107000.0 0.1 1925479.0 46432.6064814799 0.0454920183291784 0.2191 0.8444 3065817 Maybridge4_004641 Oc1ccc2c(CSc3nnc([nH]3)c4cccs4)cc(=O)oc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G03 compound treatment 2427767.0 136000.0 0.14 2562483.0 67900.0 0.06 1882103.0 3056.60648147995 0.00299468861684586 0.1213 0.7692 1387671 Maybridge4_004642 CN(CCOC(=O)Nc1cccc(Cl)c1)c2ccc(C#N)cn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G04 compound treatment 2705770.0 414000.0 0.44 2974533.0 480000.0 0.44 2006137.0 127090.60648148 0.124516124284945 0.58 0.9139 1420583 Maybridge4_004643 Clc1ccc(CSc2n[nH]c(=O)n2C3CC4CC3C=C4)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G05 compound treatment 2896812.0 605000.0 0.64 3021607.0 527000.0 0.48 2352803.0 473756.60648148 0.464159689898544 0.9182 0.9887 3178988 Maybridge4_004644 COC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)C)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G06 compound treatment 2994462.0 703000.0 0.75 3675957.0 1180000.0 1.08 2725631.0 846584.60648148 0.829435290276391 1.5352 0.9873 3065818 Maybridge4_004645 Cc1cc(nn1Cc2ccc(C)cc2)C(=O)Sc3cccc(Cl)c3Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G07 compound treatment 2914176.0 623000.0 0.66 3435578.0 941000.0 0.86 2463868.0 584821.60648148 0.572974839393661 1.2107 0.9853 3178989 Maybridge4_004646 FC(F)(F)c1cccn(CC(=O)c2ccc(Cl)cc2)c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G08 compound treatment 3117108.0 826000.0 0.88 3552225.0 1060000.0 0.97 2549292.0 670245.60648148 0.656668400195632 1.4453 0.9879 1219573 Maybridge4_004647 CC(C)(C)c1cc(NC(=O)CSc2n[nH]c(=O)n2c3ccc4OCCOc4c3)cc(c1)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G09 compound treatment 3089278.0 798000.0 0.85 3288602.0 794000.0 0.73 2736293.0 857246.60648148 0.839881309489617 1.3945 0.9977 3065819 Maybridge4_004648 CCOC(=O)c1cnc(nc1Sc2nnc([nH]2)c3cccs3)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G10 compound treatment 2972550.0 681000.0 0.72 3526714.0 1030000.0 0.95 2630212.0 751165.60648148 0.735949198801357 1.3888 0.992 1396971 Maybridge4_004649 CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)c2nnc(S)o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G11 compound treatment 1275914.0 -1020000.0 -1.08 1389606.0 -1110000.0 -1.01 1343395.0 -535651.39351852 -0.524800670445106 -1.5107 -0.9621 3065820 Maybridge4_004650 CCOC(=O)c1cc(C#N)c(Sc2ccccc2NC(=O)c3ccccc3)nc1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G12 compound treatment 1527506.0 -764000.0 -0.81 1694257.0 -800000.0 -0.73 1288021.0 -591025.39351852 -0.579052955936869 -1.2265 -0.9908 1227698 Maybridge4_004651 Cc1cccc(Cn2nc(cc2C(=O)Nc3cccnc3)C(C)(C)C)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G13 compound treatment 3028366.0 737000.0 0.78 3741572.0 1250000.0 1.14 2791829.0 912782.60648148 0.894292313337461 1.6282 0.9874 3065822 Maybridge4_004652 FC(F)(F)c1ccc(=O)n(Cc2cccc(c2)C(=O)Sc3ccccc3)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G14 compound treatment 2779848.0 488000.0 0.52 3414404.0 920000.0 0.84 2550971.0 671924.60648148 0.658313388589836 1.1664 0.9811 3178991 Maybridge4_004653 CCOC(=O)C1CCN(CC1)c2nc(c(cc2C#N)C(=O)OCC)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G15 compound treatment 2585267.0 294000.0 0.31 3623850.0 1130000.0 1.03 2412484.0 533437.60648148 0.522631728227613 1.0795 0.8991 1653461 Maybridge4_004654 CC(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G16 compound treatment 2212369.0 -79100.0 -0.08 2419403.0 -75200.0 -0.07 1771013.0 -108033.39351852 -0.105844954451741 -0.1494 -0.9849 3178992 Maybridge4_004655 CC(C)N(CCC#N)C(=S)Nc1c(C)cccc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G17 compound treatment 2509524.0 218000.0 0.23 2829767.0 335000.0 0.31 2447531.0 568484.60648148 0.556968779002883 0.6327 0.9346 3065823 Maybridge4_004656 COC(=N)NC(=S)Nc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G18 compound treatment 2171486.0 -120000.0 -0.13 2498467.0 3850.0 0.0 1836333.0 -42713.3935185201 -0.0418481456909156 -0.0957 -0.7132 1122990 Maybridge4_004657 CC(C)NC(=O)Nc1nc(Nc2ccc(Cl)cc2)n[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G19 compound treatment 2225092.0 -66400.0 -0.07 2599763.0 105000.0 0.1 1566416.0 -312630.39351852 -0.306297420496422 -0.1619 -0.4926 3178993 Maybridge4_004658 N1N=C(NC1c2cccnc2)c3cnccn3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G20 compound treatment 2006136.0 -285000.0 -0.3 2336813.0 -158000.0 -0.14 1594242.0 -284804.39351852 -0.279035093482051 -0.4197 -0.961 1235857 Maybridge4_004659 Cc1c(C#N)c(=N)n(nc1C(=O)Nc2ccccc2)c3ccc(cc3)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G21 compound treatment 1798784.0 -493000.0 -0.52 2206949.0 -288000.0 -0.26 1670871.0 -208175.39351852 -0.203958371826612 -0.5722 -0.922 3178994 Maybridge4_004660 CCOC(=O)c1sc2nc(c(cc2c1NC(=O)C)C(=O)OCC)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G22 mock treatment 2382826.0 91300.0 0.1 1806151.0 -688000.0 -0.63 1556102.0 -322944.39351852 -0.316402489166954 -0.4909 -0.689 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G23 mock treatment 1683963.0 -608000.0 -0.65 2264380.0 -230000.0 -0.21 1678531.0 -200515.39351852 -0.19645354091559 -0.608 -0.8599 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 G24 mock treatment 1628358.0 -663000.0 -0.7 1767564.0 -727000.0 -0.67 1624376.0 -254670.39351852 -0.249511519764986 -0.9356 -0.9343 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H01 mock treatment 2206839.0 -84600.0 -0.09 2539036.0 44400.0 0.04 1891682.0 12635.6064814799 0.0123796462273778 -0.0213 -0.2139 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H02 mock treatment 2766551.0 475000.0 0.5 2908086.0 413000.0 0.38 2208288.0 329241.60648148 0.322572139101381 0.6965 0.9825 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H03 mock treatment 2866621.0 575000.0 0.61 3285194.0 791000.0 0.72 2334930.0 455883.60648148 0.446648744353806 1.029 0.9821 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H04 mock treatment 2851861.0 560000.0 0.6 3211761.0 717000.0 0.66 2498387.0 619340.60648148 0.606794585897258 1.0736 0.9991 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H05 mock treatment 2889755.0 598000.0 0.64 3237424.0 743000.0 0.68 2460674.0 581627.60648148 0.569845540447212 1.0891 0.9974 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H06 mock treatment 2892240.0 601000.0 0.64 3224398.0 730000.0 0.67 2411010.0 531963.60648148 0.521187587135858 1.0556 0.9946 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H07 mock treatment 3139782.0 848000.0 0.9 3524724.0 1030000.0 0.94 2602123.0 723076.60648148 0.708429199394088 1.4745 0.9928 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H08 mock treatment 3098177.0 807000.0 0.86 3376024.0 881000.0 0.81 2806657.0 927610.60648148 0.908819941633627 1.486 0.9988 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H09 mock treatment 3411174.0 1120000.0 1.19 3602860.0 1110000.0 1.02 2685764.0 806717.60648148 0.790375878536222 1.7297 0.9869 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H10 mock treatment 3226781.0 935000.0 0.99 3565339.0 1070000.0 0.98 2642871.0 763824.60648148 0.748351764663318 1.5724 0.9924 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H11 mock treatment 3174606.0 883000.0 0.94 3717929.0 1220000.0 1.12 2799224.0 920177.60648148 0.901537512369707 1.7096 0.9953 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H12 mock treatment 2892197.0 601000.0 0.64 3417216.0 923000.0 0.85 2822898.0 943851.60648148 0.924731946702282 1.3906 0.9889 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H13 mock treatment 3175923.0 884000.0 0.94 3668491.0 1170000.0 1.08 2879854.0 1000807.60648148 0.980534185523188 1.7298 0.9984 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H14 mock treatment 3006305.0 715000.0 0.76 3596457.0 1100000.0 1.01 2794530.0 915483.60648148 0.896938599015094 1.5394 0.9934 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H15 mock treatment 2977233.0 686000.0 0.73 3750322.0 1260000.0 1.15 2564764.0 685717.60648148 0.671826982944369 1.473 0.9699 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H16 mock treatment 2968079.0 677000.0 0.72 3578328.0 1080000.0 0.99 2690328.0 811281.60648148 0.794847425308794 1.4474 0.9906 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H17 mock treatment 2870742.0 579000.0 0.62 3332657.0 838000.0 0.77 2393781.0 514734.60648148 0.504307596043692 1.09 0.9856 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H18 mock treatment 3127903.0 836000.0 0.89 3450600.0 956000.0 0.88 2167563.0 288516.60648148 0.282672107919742 1.1822 0.9238 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H19 mock treatment 2840529.0 549000.0 0.58 2615132.0 121000.0 0.11 1939689.0 60642.6064814799 0.0594141654891803 0.4349 0.7288 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H20 mock treatment 2536638.0 245000.0 0.26 2215581.0 -279000.0 -0.26 1700659.0 -178387.39351852 -0.174773789166363 -0.0981 -0.2425 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H21 mock treatment 1990986.0 -300000.0 -0.32 1852587.0 -642000.0 -0.59 1820736.0 -58310.3935185201 -0.0571291963069994 -0.557 -0.8291 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H22 mock treatment 1686782.0 -605000.0 -0.64 2293033.0 -202000.0 -0.18 1640279.0 -238767.39351852 -0.233930667809637 -0.6127 -0.865 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H23 mock treatment 1655711.0 -636000.0 -0.68 2227601.0 -267000.0 -0.24 1772096.0 -106950.39351852 -0.104783892849047 -0.5918 -0.815 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 H24 mock treatment 1519499.0 -772000.0 -0.82 1514846.0 -980000.0 -0.9 1687538.0 -191508.39351852 -0.187628996266038 -1.1004 -0.8942 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I01 compound treatment 1865125.0 -426000.0 -0.45 2127547.0 -367000.0 -0.34 1819582.0 -59464.3935185201 -0.0582598196583465 -0.4894 -0.8627 3178995 Maybridge4_004661 FC(F)(F)COc1ccc(cn1)C(=O)NC(=O)NN2CCOCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I02 compound treatment 1871998.0 -419000.0 -0.45 2175105.0 -320000.0 -0.29 1675516.0 -203530.39351852 -0.199407465875999 -0.5416 -0.9511 3065824 Maybridge4_004662 Oc1nnc(SCc2cc(=O)oc3cc(O)ccc23)n1c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I03 compound treatment 2841096.0 550000.0 0.58 3154083.0 659000.0 0.6 2383664.0 504617.60648148 0.494395536732099 0.9716 0.9964 3178996 Maybridge4_004663 Cc1noc(COc2ccccc2)c1C(=O)Sc3ccc(C)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I04 compound treatment 2818142.0 527000.0 0.56 3027624.0 533000.0 0.49 2407610.0 528563.60648148 0.517856461144021 0.9041 0.9984 3065825 Maybridge4_004664 Cc1c(C#N)c(Sc2ccccc2Cl)nc3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I05 compound treatment 2494338.0 203000.0 0.22 3081076.0 586000.0 0.54 2158809.0 279762.60648148 0.2740954382337 0.593 0.9256 3178997 Maybridge4_004665 COC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)Nc3ccc(Cl)cc3)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I06 compound treatment 3056432.0 765000.0 0.81 3676234.0 1180000.0 1.08 2577467.0 698420.60648148 0.684272657495636 1.4896 0.9819 1622413 Maybridge4_004666 COc1ccc(SC(=O)c2cc(C)n(Cc3c(Cl)cccc3Cl)n2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I07 compound treatment 3153113.0 862000.0 0.92 3466133.0 972000.0 0.89 2732085.0 853038.60648148 0.835758551203249 1.5252 0.9993 3178998 Maybridge4_004667 FC(F)(F)c1ccc(=O)n(CC(=O)c2ccc(C#N)cc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I08 compound treatment 3023910.0 732000.0 0.78 3665906.0 1170000.0 1.07 2480089.0 601042.60648148 0.588867249603541 1.4091 0.9713 3065827 Maybridge4_004668 CSc1n[nH]c(=O)n1c2ccc3OCCOc3c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I09 compound treatment 2827941.0 536000.0 0.57 3078470.0 584000.0 0.54 2255983.0 376936.60648148 0.369300978566285 0.8513 0.9845 3065847 Maybridge4_004669 CCOC(=O)c1cc(C#N)c(Sc2n[nH]c(=O)n2Cc3ccc(cc3)C(F)(F)F)nc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I10 compound treatment 2881510.0 590000.0 0.63 3621105.0 1130000.0 1.03 2564920.0 685873.60648148 0.671979822842818 1.346 0.9738 3065848 Maybridge4_004670 CC(C)(C)NC(=O)[C@H]1C[C@H]2CCCC[C@H]2CN1C(=O)C3(CC4CC5CC(C4)C3)C5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I11 compound treatment 2897228.0 606000.0 0.64 3455386.0 961000.0 0.88 2635915.0 756868.60648148 0.741536672781195 1.3081 0.9918 3065849 Maybridge4_004671 FC(F)(F)c1ccc(nc1)C(=N)NC(=O)c2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I12 compound treatment 1982370.0 -309000.0 -0.33 2319177.0 -175000.0 -0.16 1885501.0 6454.60648147995 0.00632385512280551 -0.2788 -0.7623 1418931 Maybridge4_004672 Cc1cc(C)c(Cn2nc(cc2C(=O)NN3CCOCC3)C(C)(C)C)c(C)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I13 compound treatment 2733901.0 442000.0 0.47 3002743.0 508000.0 0.47 2324157.0 445110.60648148 0.436093973674376 0.7921 0.9995 3065850 Maybridge4_004673 FC(F)(F)c1ccc(=O)n(Cc2cccc(c2)C(=O)NC(=N)c3ccc(Cl)cc3)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I14 compound treatment 2891213.0 600000.0 0.64 3266417.0 772000.0 0.71 2242716.0 363669.60648148 0.356302728997549 0.982 0.966 1208016 Maybridge4_004674 COC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I15 compound treatment 2657812.0 366000.0 0.39 3236859.0 742000.0 0.68 2271302.0 392255.60648148 0.384309660645389 0.8394 0.9616 1224162 Maybridge4_004675 CC(C)(C)C(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I16 compound treatment 2702700.0 411000.0 0.44 3074023.0 579000.0 0.53 2265518.0 386471.60648148 0.378642827487511 0.7775 0.9904 3065852 Maybridge4_004676 CCN(C(=S)Nc1ccc(C)cc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I17 compound treatment 2729390.0 438000.0 0.47 3035838.0 541000.0 0.5 2509326.0 630279.60648148 0.617511993904524 0.9116 0.9923 3178999 Maybridge4_004677 Clc1ccc(cc1)c2nnc(Sc3nc(ns3)c4cccs4)[nH]2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I18 compound treatment 1651765.0 -640000.0 -0.68 2050175.0 -444000.0 -0.41 1425722.0 -453324.39351852 -0.444141373524523 -0.8841 -0.9732 3065853 Maybridge4_004678 CCCNC(=O)Nc1nc(Nc2ccc(Cl)cc2)n[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I19 compound treatment 2273228.0 -18300.0 -0.02 2034763.0 -460000.0 -0.42 1921620.0 42573.6064814799 0.0417111903284432 -0.2304 -0.5436 3179000 Maybridge4_004679 FC(F)(F)c1ccncc1C(=O)NC(=N)c2ccccn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I20 compound treatment 1792085.0 -499000.0 -0.53 1997784.0 -497000.0 -0.46 1939593.0 60546.6064814799 0.0593201101670579 -0.535 -0.7624 3179001 Maybridge4_004680 CC(Sc1ccc(C)cc1)C(=O)Nc2ccc(cc2)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I21 compound treatment 1554628.0 -737000.0 -0.78 1462648.0 -1030000.0 -0.95 1251927.0 -627119.39351852 -0.614415797569037 -1.3528 -0.9853 3065854 Maybridge4_004681 Sc1nnc(s1)c2cnccn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I22 mock treatment 2023006.0 -268000.0 -0.29 1755547.0 -739000.0 -0.68 1241666.0 -637380.39351852 -0.624468939863814 -0.9163 -0.9501 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I23 mock treatment 1540456.0 -751000.0 -0.8 1956609.0 -538000.0 -0.49 1483868.0 -395178.39351852 -0.387173240606475 -0.969 -0.9548 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 I24 mock treatment 1425311.0 -866000.0 -0.92 1667650.0 -827000.0 -0.76 1612491.0 -266555.39351852 -0.261155764592334 -1.1198 -0.9174 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J01 mock treatment 1880259.0 -411000.0 -0.44 2293749.0 -201000.0 -0.18 1731996.0 -147050.39351852 -0.14407158469395 -0.4418 -0.8914 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J02 mock treatment 2282987.0 -8500.0 -0.01 2307448.0 -187000.0 -0.17 1704831.0 -174215.39351852 -0.170686301625791 -0.2028 -0.8375 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J03 mock treatment 2305727.0 14200.0 0.02 2713737.0 219000.0 0.2 1874996.0 -4050.39351852005 -0.00396834444903268 0.1224 0.6076 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J04 mock treatment 2742333.0 451000.0 0.48 2990026.0 495000.0 0.45 1980637.0 101590.60648148 0.0995326793461656 0.5962 0.8932 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J05 mock treatment 2723562.0 432000.0 0.46 3079365.0 585000.0 0.54 2188567.0 309520.60648148 0.303250628605786 0.7496 0.9759 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J06 mock treatment 2773866.0 482000.0 0.51 3050532.0 556000.0 0.51 2170831.0 291784.60648148 0.285873907843661 0.7551 0.9716 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J07 mock treatment 2497311.0 206000.0 0.22 3459827.0 965000.0 0.88 2526585.0 647538.60648148 0.634421377284853 1.0033 0.9036 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J08 mock treatment 2994755.0 703000.0 0.75 3479232.0 985000.0 0.9 2422151.0 543104.60648148 0.532102903216757 1.2597 0.9789 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J09 mock treatment 2805522.0 514000.0 0.55 3192402.0 698000.0 0.64 2384291.0 505244.60648148 0.495009835554711 0.9704 0.9944 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J10 mock treatment 2845521.0 554000.0 0.59 3344299.0 850000.0 0.78 2321153.0 442106.60648148 0.433150825886294 1.0396 0.9734 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J11 mock treatment 2580771.0 289000.0 0.31 3365038.0 870000.0 0.8 2174790.0 295743.60648148 0.289752710138274 0.8053 0.8922 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J12 mock treatment 2508453.0 217000.0 0.23 3128868.0 634000.0 0.58 2425708.0 546661.60648148 0.535587848849982 0.7779 0.9449 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J13 mock treatment 2764590.0 473000.0 0.5 2977062.0 482000.0 0.44 2467057.0 588010.60648148 0.576099239625417 0.8781 0.9942 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J14 mock treatment 2757949.0 466000.0 0.5 2726716.0 232000.0 0.21 2142940.0 263893.60648148 0.25854789753827 0.5583 0.9333 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J15 mock treatment 2646731.0 355000.0 0.38 3252066.0 757000.0 0.69 2223374.0 344327.60648148 0.33735254107575 0.8135 0.9468 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J16 mock treatment 2862473.0 571000.0 0.61 3034497.0 540000.0 0.49 2210196.0 331149.60648148 0.324441488628565 0.8233 0.9715 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J17 mock treatment 2822736.0 531000.0 0.56 2850261.0 356000.0 0.33 2127677.0 248630.60648148 0.243594081063737 0.6548 0.9409 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J18 mock treatment 2579025.0 288000.0 0.31 2446219.0 -48400.0 -0.04 1890601.0 11554.6064814799 0.0113205441105613 0.1573 0.5093 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J19 mock treatment 2551439.0 260000.0 0.28 2375756.0 -119000.0 -0.11 1703586.0 -175460.39351852 -0.171906081584567 -0.0026 -0.0077 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J20 mock treatment 2196358.0 -95100.0 -0.1 1907462.0 -587000.0 -0.54 1804807.0 -74239.3935185201 -0.0727355215787567 -0.411 -0.7442 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J21 mock treatment 2050093.0 -241000.0 -0.26 1707820.0 -787000.0 -0.72 1518442.0 -360604.39351852 -0.353299608241245 -0.7684 -0.9116 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J22 mock treatment 1644449.0 -647000.0 -0.69 1849189.0 -645000.0 -0.59 1476537.0 -402509.39351852 -0.394355736090639 -0.9662 -0.9769 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J23 mock treatment 1303229.0 -988000.0 -1.05 1696404.0 -798000.0 -0.73 1203106.0 -675940.39351852 -0.662247827583003 -1.411 -0.9792 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 J24 mock treatment 1384988.0 -906000.0 -0.96 1786468.0 -708000.0 -0.65 1382633.0 -496413.39351852 -0.486357517013427 -1.2116 -0.9622 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K01 compound treatment 1735001.0 -556000.0 -0.59 2189176.0 -305000.0 -0.28 1483062.0 -395984.39351852 -0.387962913415128 -0.727 -0.9558 3065855 Maybridge4_004682 Oc1c/c(=N\c2ccc(Cl)cc2)/nc(COc3ccccc3)[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K02 compound treatment 2288188.0 -3300.0 0.0 2346583.0 -148000.0 -0.14 1629627.0 -249419.39351852 -0.244366889593475 -0.2214 -0.7922 3179002 Maybridge4_004683 Cc1cc(nn1C(C)(C)C)C(=O)Sc2cccc(c2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K03 compound treatment 2243262.0 -48200.0 -0.05 2451065.0 -43600.0 -0.04 1668496.0 -210550.39351852 -0.206285261306204 -0.1717 -0.794 3179003 Maybridge4_004684 Cc1noc(COc2ccccc2)c1C(=O)Sc3ccc(F)cc3F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K04 compound treatment 2123601.0 -168000.0 -0.18 2343173.0 -151000.0 -0.14 1816621.0 -62425.3935185201 -0.0611608385000612 -0.2184 -0.9329 3065857 Maybridge4_004685 Cc1c(C#N)c(Sc2cccc(c2)C(F)(F)F)nc3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K05 compound treatment 1910597.0 -381000.0 -0.4 2070909.0 -424000.0 -0.39 1564435.0 -314611.39351852 -0.308238291258137 -0.6358 -0.9935 3179004 Maybridge4_004686 CSc1nc(CSc2ccc(Cl)cc2)nc(C3CC3)c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K06 compound treatment 2741123.0 450000.0 0.48 2894283.0 400000.0 0.37 2240424.0 361377.60648148 0.354057158181875 0.6917 0.9904 3065858 Maybridge4_004687 Cc1cc(nn1Cc2c(Cl)cccc2Cl)C(=O)SCc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K07 compound treatment 2562419.0 271000.0 0.29 2808505.0 314000.0 0.29 1950580.0 71533.6064814799 0.0700845458353859 0.3728 0.9026 3179005 Maybridge4_004688 CCOC(=O)c1cc(C#N)c(Oc2ccc(C)cc2)nc1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K08 compound treatment 2511415.0 220000.0 0.23 2746108.0 251000.0 0.23 1825587.0 -53459.3935185201 -0.0523764633109987 0.2378 0.7153 3065859 Maybridge4_004689 CC(C)OC(=O)Nc1cc(Cl)cc(Cl)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K09 compound treatment 2570008.0 279000.0 0.3 2931671.0 437000.0 0.4 2142000.0 262953.60648148 0.257626939175821 0.5509 0.9824 3179006 Maybridge4_004690 FC(F)(F)C1CCN(CC1)c2ncccc2NC(=S)Nc3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K10 compound treatment 801487.0 -1490000.0 -1.58 859312.0 -1640000.0 -1.5 705436.0 -1173610.39351852 -1.14983649592348 -2.4433 -0.9913 1235731 Maybridge4_004691 S=C(NC1CCCC1)N2CCCN(CC2)c3ccc(C#N)cn3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K11 compound treatment 2824363.0 533000.0 0.57 3015483.0 521000.0 0.48 2407724.0 528677.60648148 0.517968151839041 0.9016 0.9976 3179007 Maybridge4_004692 FC(F)(F)c1ccc(nc1)C(=N)NC(=O)c2cccc(c2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K12 compound treatment 2437323.0 146000.0 0.15 2733656.0 239000.0 0.22 1994468.0 115421.60648148 0.113083503932372 0.2812 0.9658 1285775 Maybridge4_004693 Cc1onc(c1c2csc(CCn3c(=O)oc4ccccc34)n2)c5c(Cl)cccc5Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K13 compound treatment 2468343.0 177000.0 0.19 3268027.0 773000.0 0.71 2426476.0 547429.60648148 0.536340291426962 0.8274 0.9107 3065861 Maybridge4_004694 NNC(=O)c1cccc(n1)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K14 compound treatment 2843941.0 552000.0 0.59 3021666.0 527000.0 0.48 2322283.0 443236.60648148 0.434257935407111 0.8685 0.992 3179092 Maybridge4_004695 CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCN3CCOCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K15 compound treatment 2908367.0 617000.0 0.66 3171978.0 677000.0 0.62 2357942.0 478895.60648148 0.469194588860912 1.0078 0.9905 3065862 Maybridge4_004696 FC(F)(F)c1ccc(nc1)c2nnc(S)s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K16 compound treatment 2449228.0 158000.0 0.17 2919772.0 425000.0 0.39 2197083.0 318036.60648148 0.3115941194724 0.5016 0.9531 3065863 Maybridge4_004697 CC(C)N(CCC#N)C(=S)Nc1ccc(Cl)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K17 compound treatment 2631875.0 340000.0 0.36 2592182.0 97600.0 0.09 2325748.0 446701.60648148 0.437652744689968 0.5131 0.8928 3179093 Maybridge4_004698 CC(C)C(=N)NC(=S)Nc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K18 compound treatment 2367997.0 76500.0 0.08 2679874.0 185000.0 0.17 2089056.0 210009.60648148 0.205755429025283 0.2638 0.9458 1330597 Maybridge4_004699 CS(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K19 compound treatment 2106747.0 -185000.0 -0.2 2409472.0 -85100.0 -0.08 1814998.0 -64048.3935185201 -0.062750961289694 -0.1946 -0.8831 3179094 Maybridge4_004700 N=C(NC(=O)N1CCOCC1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K20 compound treatment 1962831.0 -329000.0 -0.35 2368636.0 -126000.0 -0.12 1621675.0 -257371.39351852 -0.252157805442619 -0.4139 -0.928 3065864 Maybridge4_004701 CN(C)/C=N/c1ncc(Br)cc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K21 compound treatment 1841255.0 -450000.0 -0.48 2496537.0 1920.0 0.0 1759699.0 -119347.39351852 -0.116929766061049 -0.3427 -0.6958 3179095 Maybridge4_004702 CC(C)(C)C(=O)CSc1nnc(s1)c2cnccn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K22 mock treatment 2150837.0 -141000.0 -0.15 2275374.0 -219000.0 -0.2 1801212.0 -77834.3935185201 -0.0762576974436551 -0.2463 -0.941 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K23 mock treatment 1614109.0 -677000.0 -0.72 2040979.0 -454000.0 -0.42 1661350.0 -217696.39351852 -0.213286504346695 -0.7788 -0.9074 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 K24 mock treatment 1665262.0 -626000.0 -0.67 2200186.0 -294000.0 -0.27 1607125.0 -271921.39351852 -0.266413065201804 -0.6938 -0.9058 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L01 mock treatment 1958086.0 -333000.0 -0.35 1995500.0 -499000.0 -0.46 1548591.0 -330455.39351852 -0.323761338380098 -0.6556 -0.9888 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L02 mock treatment 2114224.0 -177000.0 -0.19 2366917.0 -128000.0 -0.12 1449624.0 -429422.39351852 -0.420723557801908 -0.4192 -0.8815 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L03 mock treatment 2123920.0 -168000.0 -0.18 2379709.0 -115000.0 -0.11 1627838.0 -251208.39351852 -0.246119649710944 -0.3057 -0.9508 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L04 mock treatment 2228701.0 -62800.0 -0.07 2546351.0 51700.0 0.05 1796636.0 -82410.3935185201 -0.0807410011314925 -0.0578 -0.5024 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L05 mock treatment 2275546.0 -15900.0 -0.02 2455980.0 -38600.0 -0.04 1882071.0 3024.60648147995 0.00296333684280504 -0.0285 -0.7243 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L06 mock treatment 2433238.0 142000.0 0.15 2703293.0 209000.0 0.19 2087933.0 208886.60648148 0.204655177705038 0.3155 0.9921 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L07 mock treatment 2623893.0 332000.0 0.35 3085650.0 591000.0 0.54 2180058.0 301011.60648148 0.294913995939744 0.6869 0.9665 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L08 mock treatment 2769603.0 478000.0 0.51 2791079.0 296000.0 0.27 2325410.0 446363.60648148 0.437321591576662 0.7027 0.9715 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L09 mock treatment 2781761.0 490000.0 0.52 3034321.0 540000.0 0.49 2283075.0 404028.60648148 0.395844174263595 0.8149 0.9935 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L10 mock treatment 2682081.0 391000.0 0.42 2966505.0 472000.0 0.43 2281362.0 402315.60648148 0.394165874609472 0.7169 0.9993 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L11 mock treatment 2868660.0 577000.0 0.61 3371800.0 877000.0 0.8 2346057.0 467010.60648148 0.457550344033563 1.0824 0.9753 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L12 mock treatment 2828764.0 537000.0 0.57 3318539.0 824000.0 0.76 2325859.0 446812.60648148 0.437761496156172 1.0183 0.9764 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L13 mock treatment 2564226.0 273000.0 0.29 3366927.0 872000.0 0.8 2335375.0 456328.60648148 0.447084729961562 0.887 0.9233 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L14 mock treatment 2943458.0 652000.0 0.69 3044719.0 550000.0 0.5 2151159.0 272112.60648148 0.266600404752067 0.845 0.9416 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L15 mock treatment 2610022.0 319000.0 0.34 3046788.0 552000.0 0.51 2036946.0 157899.60648148 0.154701024485684 0.5769 0.9184 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L16 mock treatment 2607468.0 316000.0 0.34 2973335.0 479000.0 0.44 2231079.0 352032.60648148 0.344901460419017 0.6463 0.9923 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L17 mock treatment 2480149.0 189000.0 0.2 2803658.0 309000.0 0.28 2141642.0 262595.60648148 0.257276191203739 0.4278 0.9904 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L18 mock treatment 2536767.0 245000.0 0.26 2691340.0 197000.0 0.18 2215225.0 336178.60648148 0.329368615867667 0.4447 0.973 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L19 mock treatment 2083503.0 -208000.0 -0.22 2386793.0 -108000.0 -0.1 1736244.0 -142802.39351852 -0.139909636690031 -0.2654 -0.9493 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L20 mock treatment 2005017.0 -286000.0 -0.3 2270666.0 -224000.0 -0.21 2029876.0 150829.60648148 0.14777424190854 -0.2089 -0.5279 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L21 mock treatment 1685846.0 -606000.0 -0.64 2335228.0 -159000.0 -0.15 1742869.0 -136177.39351852 -0.133418839720643 -0.5329 -0.7915 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L22 mock treatment 1786634.0 -505000.0 -0.54 2336321.0 -158000.0 -0.15 1750975.0 -128071.39351852 -0.125477043458927 -0.4659 -0.8178 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L23 mock treatment 2113789.0 -178000.0 -0.19 1937660.0 -557000.0 -0.51 1692992.0 -186054.39351852 -0.182285478277956 -0.509 -0.8868 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 L24 mock treatment 1496006.0 -795000.0 -0.85 1715519.0 -779000.0 -0.71 1358254.0 -520792.39351852 -0.510242670117839 -1.1949 -0.9806 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M01 compound treatment 2082825.0 -209000.0 -0.22 2347598.0 -147000.0 -0.13 1700832.0 -178214.39351852 -0.174604293637955 -0.3066 -0.9804 3065865 Maybridge4_004703 FC(F)(F)c1cccn(CCc2nc(cs2)c3ccccc3)c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M02 compound treatment 2613228.0 322000.0 0.34 2727408.0 233000.0 0.21 2106962.0 227915.60648148 0.223298706086999 0.4495 0.9756 3179096 Maybridge4_004704 Cc1cc(nn1C(C)(C)C)C(=O)Sc2cccc(Br)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M03 compound treatment 2588099.0 297000.0 0.32 2843727.0 349000.0 0.32 2117286.0 238239.60648148 0.233413572186919 0.5015 0.9907 3179097 Maybridge4_004705 CN(CCOC(=O)c1ccc(Cl)cc1)c2ncc(cc2Cl)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M04 compound treatment 2447508.0 156000.0 0.17 2769349.0 275000.0 0.25 2149027.0 269980.60648148 0.264511592806597 0.3938 0.9819 3065866 Maybridge4_004706 Cc1c(C#N)c(Sc2n[nH]c(=O)n2C3CCCCC3)nc4ccccc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M05 compound treatment 2597380.0 306000.0 0.33 2710432.0 216000.0 0.2 2014374.0 135327.60648148 0.13258626687164 0.3784 0.9391 3065894 Maybridge4_004707 CCOC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)c3cccc(c3)C(F)(F)F)c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M06 compound treatment 2656023.0 365000.0 0.39 2964936.0 470000.0 0.43 2228055.0 349008.60648148 0.341938717772159 0.6699 0.9956 3065895 Maybridge4_004708 OC(C(O)c1nc2cc(C#N)ccc2[nH]1)c3nc4cc(C#N)ccc4[nH]3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M07 compound treatment 2156090.0 -135000.0 -0.14 2607135.0 113000.0 0.1 1793815.0 -85231.3935185201 -0.0835048559617786 -0.0717 -0.3666 3065896 Maybridge4_004709 CCOC(=O)c1cc(C#N)c(Sc2nnc([nH]2)C(C)(C)C)nc1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M08 compound treatment 2824368.0 533000.0 0.57 3240081.0 745000.0 0.68 2298450.0 419403.60648148 0.410907721947271 0.9586 0.9803 3065897 Maybridge4_004710 NC(=S)Cc1ccc(Cl)cc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M09 compound treatment 2222815.0 -68700.0 -0.07 2548478.0 53900.0 0.05 2096021.0 216974.60648148 0.212579338593855 0.1091 0.4741 3065898 Maybridge4_004711 FC(F)(F)C1CCN(CC1)c2ncccc2NC(=S)Nc3cccc(c3)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M10 compound treatment 819139.0 -1470000.0 -1.56 887801.0 -1610000.0 -1.47 716435.0 -1162611.39351852 -1.13906030333989 -2.4111 -0.9915 1643927 Maybridge4_004712 CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)c2nnc(S)n2CC3CCCO3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M11 compound treatment 2448524.0 157000.0 0.17 2867772.0 373000.0 0.34 1847935.0 -31111.3935185201 -0.0304811681152405 0.2762 0.7235 3065900 Maybridge4_004713 FC(F)(F)c1ccc(=O)n(Cc2cccc(C#N)c2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M12 compound treatment 2450263.0 159000.0 0.17 2800606.0 306000.0 0.28 1874820.0 -4226.39351852005 -0.00414077920625719 0.2569 0.785 1263587 Maybridge4_004714 COc1ccccc1OCc2nc(cs2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M13 compound treatment 2288210.0 -3270.0 0.0 2610442.0 116000.0 0.11 2024104.0 145057.60648148 0.142119165665927 0.1413 0.7966 3179098 Maybridge4_004715 FC(F)(F)c1ccc(cc1)C(=N)NC(=O)CCn2c(=O)oc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M14 compound treatment 2589810.0 298000.0 0.32 3062744.0 568000.0 0.52 1972540.0 93493.6064814799 0.0915997007708992 0.5365 0.8704 1136340 Maybridge4_004716 CCOc1cc(N2CCOCC2)c(OCC)cc1NS(=O)(=O)CC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M15 compound treatment 2615136.0 324000.0 0.34 2905359.0 411000.0 0.38 2172977.0 293930.60648148 0.287976436190274 0.5822 0.9941 3179099 Maybridge4_004717 FC(F)(F)c1ccc(nc1)c2nnc(SCC=C)s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M16 compound treatment 2392325.0 101000.0 0.11 2270331.0 -224000.0 -0.21 2049199.0 170152.60648148 0.166705814714502 0.0394 0.1382 1122167 Maybridge4_004718 O=C(N1CCN(CCOc2ccccc2)CC1)c3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M17 compound treatment 2157618.0 -134000.0 -0.14 2510505.0 15900.0 0.01 1725762.0 -153284.39351852 -0.150179302174278 -0.1604 -0.7736 3179100 Maybridge4_004719 FC(F)(F)COc1ccc(cn1)C(=O)NC(=N)c2ccc(cc2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M18 compound treatment 1733555.0 -558000.0 -0.59 2274825.0 -220000.0 -0.2 1353063.0 -525983.39351852 -0.515328515713023 -0.7561 -0.9324 3065901 Maybridge4_004720 CNC(=O)Nc1nc2cccnc2s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M19 compound treatment 2381903.0 90400.0 0.1 1993975.0 -501000.0 -0.46 1474037.0 -405009.39351852 -0.396805093437578 -0.4385 -0.714 1030287 Maybridge4_004721 CSc1nc(O)cc(O)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M20 compound treatment 1857443.0 -434000.0 -0.46 2326141.0 -168000.0 -0.15 1321392.0 -557654.39351852 -0.546357954326987 -0.6709 -0.9171 3179101 Maybridge4_004722 Cc1nc(N/C=N/O)c(Br)cc1Br 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M21 compound treatment 1502785.0 -789000.0 -0.84 1799258.0 -695000.0 -0.64 1247090.0 -631956.39351852 -0.619154814163895 -1.2093 -0.99 3179102 Maybridge4_004723 Cc1nc(c(s1)C(=O)Sc2ccc(C)cc2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M22 mock treatment 1970627.0 -321000.0 -0.34 1499290.0 -995000.0 -0.91 1120608.0 -758438.39351852 -0.743074660546116 -1.1525 -0.9409 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M23 mock treatment 1363269.0 -928000.0 -0.99 1433450.0 -1060000.0 -0.97 1075035.0 -804011.39351852 -0.787724485494939 -1.5857 -0.9951 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 M24 mock treatment 1267338.0 -1020000.0 -1.09 1295723.0 -1200000.0 -1.1 1018172.0 -860874.39351852 -0.843435608222539 -1.7496 -0.9933 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N01 mock treatment 2303075.0 11600.0 0.01 2422499.0 -72100.0 -0.07 1912388.0 33341.6064814799 0.0326662035176664 -0.0122 -0.163 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N02 mock treatment 2482042.0 191000.0 0.2 2709725.0 215000.0 0.2 1702523.0 -176523.39351852 -0.172947548328485 0.1309 0.395 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N03 mock treatment 2548044.0 257000.0 0.27 2734217.0 240000.0 0.22 1940277.0 61230.6064814799 0.0599902543371804 0.3188 0.8976 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N04 mock treatment 2569981.0 278000.0 0.3 2933200.0 439000.0 0.4 2011313.0 132266.60648148 0.129587273736047 0.4777 0.9264 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N05 mock treatment 2706904.0 415000.0 0.44 3068356.0 574000.0 0.53 2295978.0 416931.60648148 0.408485797402617 0.7943 0.9942 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N06 mock treatment 2456373.0 165000.0 0.18 3117155.0 623000.0 0.57 2245389.0 366342.60648148 0.358921581872896 0.6378 0.9158 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N07 mock treatment 2830054.0 539000.0 0.57 3226800.0 732000.0 0.67 2228734.0 349687.60648148 0.342603963227588 0.9156 0.9678 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N08 mock treatment 2706122.0 415000.0 0.44 3333953.0 839000.0 0.77 2245121.0 366074.60648148 0.358659010765304 0.9056 0.947 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N09 mock treatment 2670485.0 379000.0 0.4 3224977.0 730000.0 0.67 2366653.0 487606.60648148 0.477729129600586 0.8948 0.9772 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N10 mock treatment 2902371.0 611000.0 0.65 3400970.0 906000.0 0.83 2202788.0 323741.60648148 0.317183552938115 1.0375 0.9424 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N11 mock treatment 2602009.0 311000.0 0.33 2954396.0 460000.0 0.42 2216639.0 337592.60648148 0.330753972383096 0.6247 0.993 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N12 mock treatment 2680166.0 389000.0 0.41 3083484.0 589000.0 0.54 2076868.0 197821.60648148 0.193814322087485 0.6619 0.9367 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N13 mock treatment 2666236.0 375000.0 0.4 2978308.0 484000.0 0.44 2183003.0 303956.60648148 0.297799338894438 0.6578 0.9874 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N14 mock treatment 2661038.0 370000.0 0.39 2913517.0 419000.0 0.38 2006308.0 127261.60648148 0.124683660327475 0.5204 0.924 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N15 mock treatment 2747159.0 456000.0 0.48 3030581.0 536000.0 0.49 2158451.0 279404.60648148 0.273744690261619 0.7212 0.9719 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N16 mock treatment 2510155.0 219000.0 0.23 2553177.0 58600.0 0.05 2082389.0 203342.60648148 0.199223482852465 0.2802 0.9016 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N17 mock treatment 2383369.0 91900.0 0.1 2633309.0 139000.0 0.13 1721288.0 -157758.39351852 -0.15456267208236 0.0405 0.182 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N18 mock treatment 2179204.0 -112000.0 -0.12 2682366.0 188000.0 0.17 1607794.0 -271252.39351852 -0.265757617175763 -0.123 -0.3635 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N19 mock treatment 1707270.0 -584000.0 -0.62 2113165.0 -381000.0 -0.35 1416810.0 -462236.39351852 -0.452872842594892 -0.8217 -0.9733 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N20 mock treatment 2089970.0 -202000.0 -0.21 2057991.0 -437000.0 -0.4 1515208.0 -363838.39351852 -0.356468096905246 -0.5605 -0.9712 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N21 mock treatment 2095383.0 -196000.0 -0.21 1705176.0 -789000.0 -0.72 1322057.0 -556989.39351852 -0.545706425272701 -0.8531 -0.9174 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N22 mock treatment 1410707.0 -881000.0 -0.94 1681163.0 -813000.0 -0.75 1269518.0 -609528.39351852 -0.597181139533035 -1.3156 -0.9837 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N23 mock treatment 1645104.0 -646000.0 -0.69 1472707.0 -1020000.0 -0.94 973403.0 -905643.39351852 -0.887297719848586 -1.4496 -0.9918 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 N24 mock treatment 1561552.0 -730000.0 -0.78 1349992.0 -1140000.0 -1.05 1176108.0 -702938.39351852 -0.688698927444068 -1.4511 -0.9836 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O01 compound treatment 2399392.0 108000.0 0.11 2409690.0 -84900.0 -0.08 1746685.0 -132361.39351852 -0.129680140666275 -0.0536 -0.2824 3065902 Maybridge4_004724 Cc1nn(c(N)c1C(=S)N)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O02 compound treatment 2304150.0 12700.0 0.01 2579538.0 84900.0 0.08 1734326.0 -144720.39351852 -0.141788783646603 -0.0292 -0.1797 1470895 Maybridge4_004725 CCOC(=O)c1cc(Sc2ccccc2NC(=O)c3ccccc3)cc(n1)C(=O)OCC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O03 compound treatment 2345829.0 54300.0 0.06 2423038.0 -71600.0 -0.07 1675569.0 -203477.39351852 -0.199355539500244 -0.1196 -0.5496 3065903 Maybridge4_004726 Cc1cc(no1)c2nnc(SCC(=O)c3ccccc3Cl)n2C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O04 compound treatment 2022264.0 -269000.0 -0.29 2166997.0 -328000.0 -0.3 1519005.0 -360041.39351852 -0.352748012966715 -0.5422 -0.9958 1417512 Maybridge4_004727 Cc1c(C#N)c(Sc2ccccc2NC(=O)c3ccccc3)nc4ccccc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O05 compound treatment 2243286.0 -48200.0 -0.05 2617921.0 123000.0 0.11 1829303.0 -49743.3935185201 -0.0487357385505084 0.0075 0.0565 3065905 Maybridge4_004728 CC(C)(C)c1ccc(OCC(=N)NC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O06 compound treatment 2554135.0 263000.0 0.28 2894882.0 400000.0 0.37 2111722.0 232675.60648148 0.227962282475571 0.5045 0.9812 1176898 Maybridge4_004729 OC(C(O)c1nc2cc(Cl)ccc2[nH]1)c3nc4cc(Cl)ccc4[nH]3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O07 compound treatment 2660614.0 369000.0 0.39 2900354.0 406000.0 0.37 2078533.0 199486.60648148 0.195445594080546 0.554 0.9639 3065906 Maybridge4_004730 Cc1nc(nc(Sc2nnc([nH]2)c3cccs3)c1C)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O08 compound treatment 2551534.0 260000.0 0.28 2970830.0 476000.0 0.44 2190012.0 310965.60648148 0.304666357152317 0.5874 0.9795 3179103 Maybridge4_004731 CC(=O)N/C(=C\c1ccc2ccccc2c1)/C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O09 compound treatment 2667574.0 376000.0 0.4 2534775.0 40200.0 0.04 3138713.0 1259666.60648148 1.23414946291171 0.9645 0.7432 3179104 Maybridge4_004732 NC(=O)C1=CN(Cc2ccccc2)CCC1C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O10 compound treatment 2484633.0 193000.0 0.21 2593745.0 99100.0 0.09 1693266.0 -185780.39351852 -0.182017028712731 0.0659 0.2279 3065908 Maybridge4_004733 CC(C)(C)c1cc(c2nnc(o2)c3cccs3)n(Cc4ccc(F)cc4)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O11 compound treatment 2610913.0 319000.0 0.34 2821678.0 327000.0 0.3 2100666.0 221619.60648148 0.217130244544468 0.4944 0.9844 3179105 Maybridge4_004734 FC(F)(F)COc1cc(cc(OCC(F)(F)F)n1)c2nnc(S)n2Cc3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O12 compound treatment 2181109.0 -110000.0 -0.12 2695765.0 201000.0 0.18 1795060.0 -83986.3935185201 -0.0822850760030029 -0.0088 -0.0377 3065960 Maybridge4_004735 Clc1ccc(Sc2c[nH]nc2c3ccc4OCCOc4c3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O13 compound treatment 2274723.0 -16800.0 -0.02 2526597.0 32000.0 0.03 1698669.0 -180377.39351852 -0.176723477614526 -0.0954 -0.5299 1741446 Maybridge4_004736 CC(C)(C)NC(=O)N1CCN(CC1)c2ccc(C#N)cn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O14 compound treatment 2365818.0 74300.0 0.08 2453987.0 -40600.0 -0.04 1670567.0 -208479.39351852 -0.20425621368 -0.0938 -0.4223 1571449 Maybridge4_004737 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O15 compound treatment 2019997.0 -271000.0 -0.29 2392162.0 -102000.0 -0.09 1592462.0 -286584.39351852 -0.280779035913072 -0.3829 -0.9262 3065932 Maybridge4_004738 N/C(=N\O)/c1ccc(Cl)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O16 compound treatment 1578271.0 -713000.0 -0.76 1726426.0 -768000.0 -0.7 1412923.0 -466123.39351852 -0.456681103397913 -1.1077 -0.9796 1468379 Maybridge4_004739 CC(C)c1ccc(NC(=O)N2CCCN(CCOc3ccccc3)CC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O17 compound treatment 2060643.0 -231000.0 -0.25 2633517.0 139000.0 0.13 1825314.0 -53732.3935185201 -0.0526439331332844 -0.0985 -0.3502 3065933 Maybridge4_004740 COc1ccc(OCC(=N)NC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O18 compound treatment 2006896.0 -285000.0 -0.3 2099817.0 -395000.0 -0.36 1556743.0 -322303.39351852 -0.315774473943199 -0.5658 -0.997 3065934 Maybridge4_004741 NC(=C(C#N)C#N)Nc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O19 compound treatment 1642179.0 -649000.0 -0.69 1698234.0 -796000.0 -0.73 1564186.0 -314860.39351852 -0.308482247249892 -0.9978 -0.9497 3065935 Maybridge4_004742 Oc1nnc(SCC(=O)N2CCC(CC2)C(F)(F)F)n1c3cccc(c3)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O20 compound treatment 1812968.0 -479000.0 -0.51 1650797.0 -844000.0 -0.77 1300463.0 -578583.39351852 -0.566862994292622 -1.0673 -0.9834 3065936 Maybridge4_004743 Cc1cc(Br)cnc1N/C=N/O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O21 compound treatment 1467723.0 -824000.0 -0.88 1439592.0 -1060000.0 -0.97 1218978.0 -660068.39351852 -0.646697347658756 -1.437 -0.9871 3179106 Maybridge4_004744 Cc1nc(c(s1)C(=O)Sc2cccc(c2)C(F)(F)F)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O22 mock treatment 1479259.0 -812000.0 -0.86 1436679.0 -1060000.0 -0.97 1158336.0 -720710.39351852 -0.706110918951989 -1.4658 -0.9919 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O23 mock treatment 1402259.0 -889000.0 -0.94 1621338.0 -873000.0 -0.8 1100832.0 -778214.39351852 -0.762450056903344 -1.4478 -0.9956 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 O24 mock treatment 1186078.0 -1110000.0 -1.17 1329695.0 -1160000.0 -1.07 1025453.0 -853593.39351852 -0.836302099885313 -1.7774 -0.9907 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P01 mock treatment 1954559.0 -337000.0 -0.36 2037186.0 -457000.0 -0.42 1514417.0 -364629.39351852 -0.357243073569817 -0.655 -0.9971 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P02 mock treatment 2172812.0 -119000.0 -0.13 2360756.0 -134000.0 -0.12 1734544.0 -144502.39351852 -0.14157519968595 -0.2254 -0.998 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P03 mock treatment 2029519.0 -262000.0 -0.28 2436590.0 -58000.0 -0.05 1690815.0 -188231.39351852 -0.18441837865567 -0.2979 -0.881 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P04 mock treatment 2294806.0 3320.0 0.0 2609894.0 115000.0 0.11 1821605.0 -57441.3935185201 -0.0562777996932033 0.0305 0.255 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P05 mock treatment 2280911.0 -10600.0 -0.01 2385964.0 -109000.0 -0.1 1813923.0 -65123.3935185201 -0.0638041849488779 -0.1008 -0.8486 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P06 mock treatment 2282800.0 -8680.0 -0.01 2565646.0 71000.0 0.07 1953378.0 74331.6064814799 0.0728258665780802 0.0743 0.7573 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P07 mock treatment 2233214.0 -58300.0 -0.06 2801266.0 307000.0 0.28 1955733.0 76686.6064814799 0.0751331611988968 0.1699 0.5712 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P08 mock treatment 2325175.0 33700.0 0.04 2739032.0 244000.0 0.22 2465532.0 586485.60648148 0.574605131643784 0.4817 0.7798 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P09 mock treatment 2235075.0 -56400.0 -0.06 2846753.0 352000.0 0.32 2099244.0 220197.60648148 0.215737050085529 0.2763 0.7034 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P10 mock treatment 2203852.0 -87600.0 -0.09 2573184.0 78600.0 0.07 2068336.0 189289.60648148 0.185455155333851 0.0949 0.4319 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P11 mock treatment 2122161.0 -169000.0 -0.18 2491189.0 -3430.0 0.0 1921457.0 42410.6064814799 0.0415514922294227 -0.0817 -0.4424 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P12 mock treatment 2306642.0 15200.0 0.02 2500168.0 5550.0 0.01 1803017.0 -76029.3935185201 -0.0744892614391651 -0.0308 -0.4028 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P13 mock treatment 2364030.0 72500.0 0.08 2504477.0 9860.0 0.01 1789624.0 -89422.3935185201 -0.0876109586181873 -9.0E-4 -0.0073 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P14 mock treatment 2135480.0 -156000.0 -0.17 2587922.0 93300.0 0.09 1945809.0 66762.6064814799 0.0654101922744873 -0.0086 -0.0434 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P15 mock treatment 2119988.0 -171000.0 -0.18 2222978.0 -272000.0 -0.25 1705702.0 -173344.39351852 -0.169832945526117 -0.347 -0.9853 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P16 mock treatment 2164409.0 -127000.0 -0.14 2085608.0 -409000.0 -0.37 1613755.0 -265291.39351852 -0.259917369517722 -0.4444 -0.9343 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P17 mock treatment 2111776.0 -180000.0 -0.19 2220855.0 -274000.0 -0.25 1478815.0 -400231.39351852 -0.392123881676108 -0.4815 -0.9569 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P18 mock treatment 2050322.0 -241000.0 -0.26 2231445.0 -263000.0 -0.24 1409939.0 -469107.39351852 -0.459604656327219 -0.5526 -0.9546 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P19 mock treatment 1944871.0 -347000.0 -0.37 2367449.0 -127000.0 -0.12 1527377.0 -351669.39351852 -0.344545605083285 -0.4789 -0.9251 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P20 mock treatment 1734766.0 -557000.0 -0.59 1825082.0 -670000.0 -0.61 1166002.0 -713044.39351852 -0.698600209583335 -1.0992 -0.9974 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P21 mock treatment 1618867.0 -673000.0 -0.71 1748276.0 -746000.0 -0.68 1197738.0 -681308.39351852 -0.667507087678351 -1.1929 -0.9996 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P22 mock treatment 1627421.0 -664000.0 -0.71 1352283.0 -1140000.0 -1.05 1139855.0 -739191.39351852 -0.724217548203502 -1.43 -0.9825 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P23 mock treatment 1231310.0 -1060000.0 -1.13 1347047.0 -1150000.0 -1.05 1240728.0 -638318.39351852 -0.625387938740386 -1.6187 -0.9732 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2062 P24 mock treatment 1244842.0 -1050000.0 -1.11 1452231.0 -1040000.0 -0.96 1089650.0 -789396.39351852 -0.773405542444733 -1.6402 -0.9895 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A01 compound treatment 2570667.0 1010000.0 1.07 2422183.0 792000.0 0.73 2660483.0 1209836.96875 1.18532922720255 1.7226 0.9812 1360118 TimTec1_000001 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccncc4)C(=O)OC5CCCC5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A02 compound treatment 2320665.0 759000.0 0.81 2589893.0 960000.0 0.88 2434777.0 984130.96875 0.964195367463251 1.5303 0.9974 1352805 TimTec1_000002 CCOC(=O)c1cc2ccccc2oc1=N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A03 compound treatment 1259352.0 -302000.0 -0.32 1276059.0 -354000.0 -0.32 1224879.0 -225767.03125 -0.221193654675529 -0.5004 -0.9865 1269647 TimTec1_000003 CN1C2CCC1CC(C2)NC3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A04 compound treatment 2605003.0 1040000.0 1.11 2592810.0 962000.0 0.88 2811643.0 1360996.96875 1.33342716982787 1.9195 0.9865 1717432 TimTec1_000004 NC1=C(C#N)C2=C(CCCC2)C(c3ccccc3)C1(C#N)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A05 compound treatment 2440024.0 879000.0 0.93 2658805.0 1030000.0 0.94 2677946.0 1227299.96875 1.20243847814239 1.7776 0.9927 1640292 TimTec1_000005 CC1C2CC(C(C2=O)S(=O)(=O)N3CCOCC3)C1(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A06 compound treatment 1284528.0 -277000.0 -0.29 1263592.0 -367000.0 -0.34 1296610.0 -154036.03125 -0.150915713934213 -0.4509 -0.9566 1432692 TimTec1_000006 CC(=C)C[N+](C)(C)Cc1c(C)ccc2ccccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A07 compound treatment 2904165.0 1340000.0 1.43 3147308.0 1520000.0 1.39 2547057.0 1096410.96875 1.07420090462898 2.2468 0.9926 3209477 TimTec1_000007 O=C1N(CSc2nc3ccccc3s2)C(=O)c4ccccc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A08 compound treatment 2911160.0 1350000.0 1.43 3231513.0 1600000.0 1.47 3010875.0 1560228.96875 1.52862331500602 2.558 0.9997 1665724 TimTec1_000008 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccccc3)C(=O)C1)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A09 compound treatment 2272197.0 711000.0 0.76 2468836.0 838000.0 0.77 2309417.0 858770.96875 0.841374792658335 1.3656 0.9989 1568897 TimTec1_000009 CCOC(=O)c1ccc(NC(=O)NC2OC(CO)C(O)C(O)C2O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A10 compound treatment 2579088.0 1020000.0 1.08 2804246.0 1170000.0 1.08 2381795.0 931148.96875 0.912286627081039 1.7723 0.9971 3082080 TimTec1_000010 Cc1cc[n+](Cc2ccccn2)c(N)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A11 compound treatment 2412169.0 851000.0 0.9 2535730.0 905000.0 0.83 2299234.0 848587.96875 0.831398070312783 1.4811 0.9992 1782663 TimTec1_000011 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2/C=C/c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A12 compound treatment 2570739.0 1010000.0 1.07 2897851.0 1270000.0 1.16 2747874.0 1297227.96875 1.27094994236509 2.0238 0.9976 3082082 TimTec1_000012 CCCC1CCCCCC1NC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A13 compound treatment 2741222.0 1180000.0 1.25 2997187.0 1370000.0 1.25 2647503.0 1196856.96875 1.17261216385724 2.1242 0.9995 3508726 TimTec1_000013 CCC(=O)NC1CC(CC=C1C)C(C)(C)NC(=O)CC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A14 compound treatment 2484908.0 924000.0 0.98 2858792.0 1230000.0 1.13 2564522.0 1113875.96875 1.0913121150547 1.8467 0.9983 3209587 TimTec1_000014 OC(=O)CCC(=O)N=S(c1ccccc1)c2ccccc2.Oc1c(cc(cc1[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A15 compound treatment 2673019.0 1110000.0 1.18 3037046.0 1410000.0 1.29 2709414.0 1258767.96875 1.23326902893978 2.1384 0.9994 1459520 TimTec1_000015 COc1ccccc1c2nnc(N)[nH]2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A16 compound treatment 2350633.0 789000.0 0.84 2319402.0 689000.0 0.63 2505084.0 1054437.96875 1.03307815425975 1.4454 0.9812 3082084 TimTec1_000016 Cc1[nH]c2ccccc2c1Sc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A17 compound treatment 1875033.0 314000.0 0.33 1979730.0 349000.0 0.32 2008404.0 557757.96875 0.546459431428661 0.6929 0.968 1172294 TimTec1_000017 Cc1cc(C)c(NC(=O)CCNC2CCCCC2)c(C)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A18 compound treatment 1873702.0 312000.0 0.33 1755669.0 125000.0 0.11 1832401.0 381754.96875 0.374021734975331 0.474 0.9236 1183562 TimTec1_000018 CCOC(=O)c1c(CN2CCOCC2)n(c3ccccc3)c4ccc(O)cc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A19 compound treatment 1622104.0 60900.0 0.06 2067874.0 438000.0 0.4 1665454.0 214807.96875 0.210456590575553 0.3904 0.8533 1230606 TimTec1_000019 CCN1CCN(CC1)c2ccc(NC(=O)c3cccc(Br)c3)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A20 compound treatment 1580509.0 19300.0 0.02 1942978.0 313000.0 0.29 1557728.0 107081.96875 0.104912802753007 0.2378 0.7777 1045901 TimTec1_000020 COC(=O)c1cc2ccccc2[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A21 compound treatment 2021678.0 460000.0 0.49 1989970.0 360000.0 0.33 2090588.0 639941.96875 0.626978625108999 0.8348 0.9696 3209588 TimTec1_000021 CSc1ccc(/C=N/n2nnnc2Nc3ccccc3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A22 compound treatment 1802408.0 241000.0 0.26 1879189.0 249000.0 0.23 1737582.0 286935.96875 0.281123489263563 0.4419 0.9964 3082088 TimTec1_000022 OC(=O)CSc1c([nH]c2ccccc12)c3cccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A23 mock treatment 1354914.0 -206000.0 -0.22 1454978.0 -175000.0 -0.16 1368374.0 -82272.03125 -0.080605441675917 -0.2659 -0.9378 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 A24 mock treatment 1516170.0 -45100.0 -0.05 1431307.0 -199000.0 -0.18 1484835.0 34188.96875 0.0334964007168338 -0.1136 -0.5932 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B01 compound treatment 2208820.0 648000.0 0.69 2374574.0 744000.0 0.68 2230764.0 780117.96875 0.764315071294814 1.2324 0.9986 1462495 TimTec1_000023 CSc1c(CC(=O)Nc2ccccc2)n(C)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B02 compound treatment 2277077.0 716000.0 0.76 2789368.0 1160000.0 1.06 2383996.0 933349.96875 0.914443041289285 1.5804 0.991 3209589 TimTec1_000024 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B03 compound treatment 2726188.0 1160000.0 1.24 2847458.0 1220000.0 1.12 2620604.0 1169957.96875 1.14625805854711 2.0205 0.999 1291339 TimTec1_000025 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(O)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B04 compound treatment 2741393.0 1180000.0 1.25 2997322.0 1370000.0 1.25 2790814.0 1340167.96875 1.31302010415612 2.2054 0.9998 1292419 TimTec1_000026 O=C(Oc1ccc(OC(=O)c2ccco2)cc1)c3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B05 compound treatment 2855497.0 1290000.0 1.38 3043816.0 1410000.0 1.3 2968989.0 1518342.96875 1.48758580227247 2.4008 0.9984 1346277 TimTec1_000027 O=C(N1CCCCC1)c2ccc(cc2)C(=O)N3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B06 compound treatment 2794807.0 1230000.0 1.31 3166023.0 1540000.0 1.41 2951076.0 1500429.96875 1.47003566701018 2.4181 0.9989 1037513 TimTec1_000028 O=C1N(C(=O)c2ccccc12)c3nccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B07 compound treatment 2867748.0 1310000.0 1.39 2988956.0 1360000.0 1.25 2941713.0 1491066.96875 1.46086233387442 2.3639 0.9978 3209590 TimTec1_000029 Cc1ccc(s1)C(=O)c2cccs2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B08 compound treatment 2507290.0 946000.0 1.01 3024700.0 1390000.0 1.28 2787808.0 1337161.96875 1.31007499688216 2.0746 0.9936 1598558 TimTec1_000030 O=C(Nc1ccccc1)C(=S)Nc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B09 compound treatment 2829784.0 1270000.0 1.35 3159962.0 1530000.0 1.4 2932437.0 1481790.96875 1.45177423837434 2.4258 0.9995 1166367 TimTec1_000031 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4cc(Br)c(OC)cc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B10 compound treatment 2883262.0 1320000.0 1.4 3211705.0 1580000.0 1.45 3120157.0 1669510.96875 1.6356915828413 2.5922 0.9978 3081103 TimTec1_000032 C/C(=N\C1CC1)/c2c(C)[nH]n(c3nc4ccccc4s3)c2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B11 compound treatment 1901901.0 341000.0 0.36 2066025.0 436000.0 0.4 2087210.0 636563.96875 0.623669053461815 0.7996 0.9701 1692568 TimTec1_000033 Fc1ccc(cc1)C(=O)CCCN2CCNCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B12 compound treatment 2548778.0 988000.0 1.05 2659940.0 1030000.0 0.94 2728024.0 1277377.96875 1.25150204503039 1.8732 0.9931 3209591 TimTec1_000034 CCN1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/N(C)C1=S 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B13 compound treatment 2630514.0 1070000.0 1.14 2962754.0 1330000.0 1.22 2844809.0 1394162.96875 1.36592132413531 2.1496 0.9971 1611433 TimTec1_000035 CC(=O)Oc1ccc2occ(C(=O)c3ccc(Br)s3)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B14 compound treatment 1913626.0 352000.0 0.37 2029185.0 399000.0 0.37 1904721.0 454074.96875 0.444876744307586 0.6841 0.996 1351179 TimTec1_000036 O=C(c1nnn(c1Nc2ccccc2)c3ccccc3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B15 compound treatment 2587567.0 1030000.0 1.09 2943578.0 1310000.0 1.2 2901844.0 1451197.96875 1.42180096264838 2.1454 0.9939 1357665 TimTec1_000037 OC(=O)c1cccc(CN2CCN(CC2)c3ccccc3)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B16 compound treatment 2697235.0 1140000.0 1.21 2758470.0 1130000.0 1.03 2517825.0 1067178.96875 1.04556105904269 1.8975 0.9974 1209399 TimTec1_000038 O=C(NCCc1ccccc1)c2ccc(cc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B17 compound treatment 2418497.0 857000.0 0.91 2450080.0 820000.0 0.75 2378450.0 927803.96875 0.909009386950835 1.4845 0.9962 3209592 TimTec1_000039 CNC(=O)CSCc1ccc(Br)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B18 compound treatment 2254924.0 694000.0 0.74 2402477.0 772000.0 0.71 2626819.0 1176172.96875 1.1523471609116 1.4994 0.9736 3209593 TimTec1_000040 O=C(Oc1nc2ccccc2s1)/C=C/c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B19 compound treatment 2195417.0 634000.0 0.67 2341231.0 711000.0 0.65 1774549.0 323902.96875 0.317341646481282 0.9484 0.9584 1421610 TimTec1_000041 CN(C(=O)Oc1cccc(c1)C(=O)Nc2ccc(C)c(C)c2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B20 compound treatment 1679369.0 118000.0 0.13 1660403.0 30100.0 0.03 1461557.0 10910.96875 0.0106899445880143 0.0946 0.7332 3209594 TimTec1_000042 COC(=O)NC(Nc1cccc(c1)C(F)(F)F)C(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B21 compound treatment 1605417.0 44200.0 0.05 1688503.0 58200.0 0.05 1587949.0 137302.96875 0.134521614105746 0.1355 0.891 1920491 TimTec1_000043 COc1ccc2nc(NC(=N)N)nc(C)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B22 compound treatment 1522156.0 -39100.0 -0.04 1439091.0 -191000.0 -0.18 1543364.0 92717.96875 0.0908397751804337 -0.0727 -0.3605 1644751 TimTec1_000044 COc1ccc(cc1)C(=O)Oc2csc(=S)n2C(=O)c3ccc(OC)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B23 mock treatment 1421511.0 -140000.0 -0.15 1422834.0 -208000.0 -0.19 1691042.0 240395.96875 0.235526252892944 -0.0595 -0.1766 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 B24 mock treatment 1328941.0 -232000.0 -0.25 1358074.0 -272000.0 -0.25 1245318.0 -205328.03125 -0.201168688749893 -0.4027 -0.9955 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C01 compound treatment 1560628.0 -602.0 0.0 1547116.0 -83200.0 -0.08 1527774.0 77127.96875 0.0755655827649214 -8.0E-4 -0.0073 1157703 TimTec1_000045 COc1ccc2C3CC(=Nc4ccccc4N3C(=O)c2c1OC)c5ccc(Br)cc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C02 compound treatment 2702732.0 1140000.0 1.21 2665687.0 1040000.0 0.95 2578075.0 1127428.96875 1.10459057110392 1.8859 0.9951 3209595 TimTec1_000046 COC(=O)CC1=CC(C)(CC(=O)OC)C(C#N)(C#N)C(=C1C#N)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C03 compound treatment 1235002.0 -326000.0 -0.35 1257491.0 -373000.0 -0.34 1189249.0 -261397.03125 -0.256101895584105 -0.5453 -0.9914 1704164 TimTec1_000047 CCCCN(C1CC2CCC(C1)N2C)C(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C04 compound treatment 2616542.0 1060000.0 1.12 2273846.0 643000.0 0.59 2110125.0 659478.96875 0.646119862903859 1.361 0.9569 1258841 TimTec1_000048 O=C1C(=C2CCCCC2C(c3ccco3)C1(C#N)C#N)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C05 compound treatment 2913298.0 1350000.0 1.44 2728296.0 1100000.0 1.01 2679447.0 1228800.96875 1.20390907229349 2.1055 0.9897 1916777 TimTec1_000049 CC1C/2CC(C(\C2=N\O)S(=O)(=O)N3CCOCC3)C1(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C06 compound treatment 2695158.0 1130000.0 1.2 2612261.0 982000.0 0.9 2516325.0 1065678.96875 1.04409144463453 1.818 0.993 3209596 TimTec1_000050 COC1OC(COC(=O)C)C(OC(=O)C)C(C#N)(C#N)C1OC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C07 compound treatment 2688213.0 1130000.0 1.2 2821419.0 1190000.0 1.09 2437934.0 987287.96875 0.967288415920965 1.8801 0.9963 1250478 TimTec1_000051 OC(COc1ccc(Nc2ccccc2)cc1)COc3ccc(Nc4ccccc4)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C08 compound treatment 2924213.0 1360000.0 1.45 3049583.0 1420000.0 1.3 2673847.0 1223200.96875 1.19842251183635 2.2791 0.997 1606069 TimTec1_000052 CC(C)C(C1C(=O)CC(C)(C)CC1=O)C2=C(O)CC(C)(C)CC2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C09 compound treatment 2235826.0 675000.0 0.72 2873925.0 1240000.0 1.14 2337072.0 886425.96875 0.868469583630176 1.5733 0.982 3081440 TimTec1_000053 CCNC(=O)c1ccc(Cl)s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C10 compound treatment 1604190.0 43000.0 0.05 1792662.0 162000.0 0.15 1790395.0 339748.96875 0.332866653089121 0.3044 0.8285 3209597 TimTec1_000054 Cc1cc[n+](CCOc2ccc(N)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C11 compound treatment 2453458.0 892000.0 0.95 3049857.0 1420000.0 1.3 2566239.0 1115592.96875 1.09299433368058 1.9295 0.9917 1677737 TimTec1_000055 CCCCC(=O)N1C(C)CC(Nc2ccccc2)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C12 compound treatment 2633855.0 1070000.0 1.14 2808542.0 1180000.0 1.08 2505167.0 1054520.96875 1.03315947292367 1.878 0.9992 3081441 TimTec1_000056 CCOC(=O)CCCc1ccc(/C=C/C(=O)O)s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C13 compound treatment 2728741.0 1170000.0 1.24 2781700.0 1150000.0 1.06 2654288.0 1203641.96875 1.17925971969683 2.0063 0.9978 3081442 TimTec1_000057 COC(=O)c1nsc(Cl)c1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C14 compound treatment 2583448.0 1020000.0 1.09 2559113.0 929000.0 0.85 2522889.0 1072242.96875 1.05052247728465 1.7251 0.9946 1003566 TimTec1_000058 S=C(Nc1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C15 compound treatment 2333403.0 772000.0 0.82 2652815.0 1020000.0 0.94 2512812.0 1062165.96875 1.04064960769061 1.6156 0.9954 1060631 TimTec1_000059 COC(=O)C1=NNC(C1)(c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C16 compound treatment 2536586.0 975000.0 1.04 2598243.0 968000.0 0.89 2260363.0 809716.96875 0.793314482539635 1.5685 0.9939 3081443 TimTec1_000060 CN(C)/C=C(\C=[N+](C)C)/c1n[nH]cc1N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C17 compound treatment 2313943.0 753000.0 0.8 2295784.0 665000.0 0.61 2237989.0 787342.96875 0.771393714027468 1.2593 0.9934 1149044 TimTec1_000061 Cc1cc(Cl)c(C(=O)N)c(C)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C18 compound treatment 1155957.0 -405000.0 -0.43 1195366.0 -435000.0 -0.4 1210126.0 -240520.03125 -0.235647802251286 -0.6148 -0.9723 1602135 TimTec1_000062 CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccncc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C19 compound treatment 1842039.0 281000.0 0.3 1583854.0 -46500.0 -0.04 1612358.0 161711.96875 0.158436159498321 0.2392 0.7023 3081444 TimTec1_000063 CCN1CCN(CC1)c2ccc(NC(=O)/C=C/c3ccccc3)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C20 compound treatment 1579406.0 18200.0 0.02 2305805.0 675000.0 0.62 1729946.0 279299.96875 0.273642172183072 0.5265 0.7776 1241763 TimTec1_000064 Oc1ccc2occ(C(=O)c3cccs3)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C21 compound treatment 1927142.0 366000.0 0.39 1913894.0 284000.0 0.26 1350487.0 -100159.03125 -0.098130103621797 0.3179 0.6652 3081445 TimTec1_000065 Nc1nnnn1/N=C\2/C(=O)Nc3ccc(Br)cc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C22 compound treatment 1701324.0 140000.0 0.15 1855455.0 225000.0 0.21 1286159.0 -164487.03125 -0.161155007387357 0.112 0.372 1336111 TimTec1_000066 COC(=O)CCc1[nH]c2ccccc2c1Sc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C23 mock treatment 1572609.0 11400.0 0.01 1532488.0 -97900.0 -0.09 1260236.0 -190410.03125 -0.186552883589238 -0.1525 -0.7355 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 C24 mock treatment 1409210.0 -152000.0 -0.16 1385806.0 -245000.0 -0.22 1244298.0 -206348.03125 -0.202168026547444 -0.3394 -0.9914 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D01 compound treatment 2052398.0 491000.0 0.52 2185037.0 555000.0 0.51 2243080.0 792433.96875 0.776381585328775 1.0431 0.9797 1420975 TimTec1_000067 CSc1c(CC(=O)Nc2ccc(C)cc2)[nH]c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D02 compound treatment 2321497.0 760000.0 0.81 2425964.0 796000.0 0.73 2370356.0 919709.96875 0.901079347604385 1.4076 0.9963 3209598 TimTec1_000068 OC(=O)CCCC=C(c1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D03 compound treatment 2043463.0 482000.0 0.51 2237528.0 607000.0 0.56 2167388.0 716741.96875 0.702222882806969 1.0226 0.9907 3209599 TimTec1_000069 Cc1[nH]c2ccccc2c1/C=N/CCc3ccncc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D04 compound treatment 2382716.0 821000.0 0.87 2793016.0 1160000.0 1.07 2532287.0 1081640.96875 1.05973010142326 1.731 0.996 3081446 TimTec1_000070 Brc1ccc(OC(=O)c2ccco2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D05 compound treatment 2145636.0 584000.0 0.62 2440462.0 810000.0 0.74 2306754.0 856107.96875 0.838765737212376 1.2714 0.9927 3081447 TimTec1_000071 CCC(=O)n1c(SC)nc2ccccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D06 compound treatment 2541939.0 981000.0 1.04 2700236.0 1070000.0 0.98 2511158.0 1060511.96875 1.03902911286987 1.7677 0.9996 3209600 TimTec1_000072 Nc1nc(SCC(=O)NC2CCCCC2)c(C#N)cc1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D07 compound treatment 2737415.0 1180000.0 1.25 3045526.0 1420000.0 1.3 2976345.0 1525698.96875 1.4947927913301 2.3334 0.9969 3081448 TimTec1_000073 CCCc1ccc(s1)/C(=N/O)/C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D08 compound treatment 2354649.0 793000.0 0.84 2731492.0 1100000.0 1.01 2717882.0 1267235.96875 1.24156549214533 1.7862 0.9877 3209601 TimTec1_000074 CCOC(=O)CCSc1ccccn1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D09 compound treatment 2600681.0 1040000.0 1.1 3199087.0 1570000.0 1.44 2660720.0 1210073.96875 1.18556142627904 2.1522 0.9935 1380002 TimTec1_000075 CCOC(=O)c1c(CN(C)C)n(c2ccccc2)c3cc(Br)c(OC)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D10 compound treatment 2078752.0 518000.0 0.55 2478006.0 848000.0 0.78 2181689.0 731042.96875 0.7162341865744 1.1795 0.9902 3081452 TimTec1_000076 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(Cl)cc4Cl)C(=O)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D11 compound treatment 2574805.0 1010000.0 1.08 3075600.0 1450000.0 1.32 2447587.0 996940.96875 0.976745874508967 1.9505 0.9917 1674072 TimTec1_000077 Cn1c(CC(=O)O)c(c2ccccc12)S(=O)(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D12 compound treatment 2629778.0 1070000.0 1.14 2739319.0 1110000.0 1.02 2477022.0 1026375.96875 1.00558460791183 1.8229 0.9984 1452087 TimTec1_000078 CCSc1nnc-2c(OC(Nc3ccccc32)C(=O)c4ccccc4)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D13 compound treatment 2658586.0 1100000.0 1.17 2711639.0 1080000.0 0.99 2576373.0 1125726.96875 1.10292304862213 1.8822 0.9978 1648799 TimTec1_000079 C(CN1CCN(CCSc2ccccc2)CC1)Sc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D14 compound treatment 2531481.0 970000.0 1.03 2788302.0 1160000.0 1.06 2679729.0 1229082.96875 1.20418535980222 1.9032 0.9976 1276972 TimTec1_000080 Clc1ccccc1CN(Cc2cccnc2)C(=S)NC(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D15 compound treatment 2400883.0 840000.0 0.89 2507753.0 877000.0 0.8 2366208.0 915561.96875 0.897015373894343 1.4973 0.9988 1186617 TimTec1_000081 Cc1c([nH]c2ccc(OCc3ccccc3)cc12)C(=O)N4CCOCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D16 compound treatment 1853128.0 292000.0 0.31 1974836.0 344000.0 0.32 1961873.0 511226.96875 0.500871012744492 0.6505 0.9733 1357113 TimTec1_000082 CC1Oc2ccccc2OC1(O)c3ccc(Br)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D17 compound treatment 2512906.0 952000.0 1.01 2349606.0 719000.0 0.66 2256300.0 805653.96875 0.789333786979389 1.4202 0.9846 3081458 TimTec1_000083 Brc1ccccc1NCn2nc(oc2=S)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D18 compound treatment 2211980.0 651000.0 0.69 1868357.0 238000.0 0.22 1972324.0 521677.96875 0.511110306197636 0.8203 0.9246 3209728 TimTec1_000084 Fc1ccccc1OC(=O)N2c3ccccc3Sc4ccccc24 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D19 compound treatment 1388581.0 -173000.0 -0.18 1586181.0 -44200.0 -0.04 1261491.0 -189155.03125 -0.185323306201075 -0.2363 -0.8954 1270584 TimTec1_000085 Cc1ccc(cc1)S(=O)(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D20 compound treatment 1842335.0 281000.0 0.3 1720812.0 90500.0 0.08 1713179.0 262532.96875 0.25721482232862 0.3688 0.9156 3081461 TimTec1_000086 FC(F)(F)c1cccc(c1)c2ccc(/C=N\C3CCS(=O)(=O)C3)o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D21 compound treatment 1219210.0 -342000.0 -0.36 1370884.0 -259000.0 -0.24 1232332.0 -218314.03125 -0.213891630552834 -0.4706 -0.9721 1450123 TimTec1_000087 CCOC(=O)c1c(C)n(c2cccc(C)c2)c3ccc(O)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D22 compound treatment 806840.0 -754000.0 -0.8 841125.0 -789000.0 -0.72 807001.0 -643645.03125 -0.630606674445219 -1.2445 -0.9953 3209729 TimTec1_000088 Cc1cccc(c1)C2Sc3ccccc3N=C4C2C(=O)c5ccccc45 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D23 mock treatment 1843782.0 283000.0 0.3 1706065.0 75700.0 0.07 1219500.0 -231146.03125 -0.226463691943203 0.0827 0.2162 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 D24 mock treatment 1293490.0 -268000.0 -0.28 1387779.0 -243000.0 -0.22 1220928.0 -229718.03125 -0.225064619026631 -0.4226 -0.9932 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E01 compound treatment 2124009.0 563000.0 0.6 2408531.0 778000.0 0.71 2141691.0 691044.96875 0.677046428509251 1.1479 0.9974 3209730 TimTec1_000089 CSc1ccccc1NC(=O)c2cc3NC4C(CCc5ccccc45)C(n3n2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E02 compound treatment 2967146.0 1410000.0 1.49 3257602.0 1630000.0 1.49 3138074.0 1687427.96875 1.65324563707535 2.6781 0.9988 3081503 TimTec1_000090 Nc1c(C#N)c(cc(c1C#N)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E03 compound treatment 2584855.0 1020000.0 1.09 2675664.0 1050000.0 0.96 2445803.0 995156.96875 0.974998013106191 1.744 0.9984 3081507 TimTec1_000091 Cc1c(Br)c(nn1CC(=O)N2CCOCC2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E04 compound treatment 2283698.0 722000.0 0.77 2312192.0 682000.0 0.62 2084554.0 633907.96875 0.621066856216427 1.1626 0.9949 1912602 TimTec1_000092 Brc1cccc(c1)C2C3CCCCC3=C(C#N)C(=O)C2(C#N)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E05 compound treatment 2636470.0 1080000.0 1.14 2954954.0 1320000.0 1.21 2714496.0 1263849.96875 1.23824808255464 2.0754 0.9994 3209731 TimTec1_000093 C[N+](C)(C)CC1CCCC1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E06 compound treatment 2844090.0 1280000.0 1.36 2936861.0 1310000.0 1.2 2843375.0 1392728.96875 1.3645163727611 2.2662 0.9982 3081510 TimTec1_000094 [N-]=[N+]=NCc1noc(n1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E07 compound treatment 2609560.0 1050000.0 1.11 2899668.0 1270000.0 1.16 2799442.0 1348795.96875 1.32147332623187 2.0777 0.9973 1182023 TimTec1_000095 CCCN(C#N)c1nc(NC(C)C)nc(NC(C)C)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E08 compound treatment 1556930.0 -4300.0 0.0 1559387.0 -71000.0 -0.07 1545665.0 95018.96875 0.0930941636825565 0.0136 0.1194 3081512 TimTec1_000096 O=C(NCC[n+]1ccc2ccccc2c1)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E09 compound treatment 2994443.0 1430000.0 1.52 3142935.0 1510000.0 1.39 3107609.0 1656962.96875 1.62339776844555 2.6169 0.9979 1029436 TimTec1_000097 OC(=O)CCC(=O)Oc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E10 compound treatment 2512209.0 951000.0 1.01 2835866.0 1210000.0 1.1 2632035.0 1181388.96875 1.15745750008026 1.8896 0.9985 3209732 TimTec1_000098 Nc1ccc(OCC(O)C[n+]2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E11 compound treatment 2865070.0 1300000.0 1.39 3121179.0 1490000.0 1.37 2894758.0 1444111.96875 1.41485850418421 2.4056 0.9999 3081515 TimTec1_000099 O=C(Nc1cccc(NC(=O)/C=C/c2ccco2)n1)/C=C/c3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E12 compound treatment 2749385.0 1190000.0 1.26 2947123.0 1320000.0 1.21 2867782.0 1417135.96875 1.3884289586678 2.2273 0.9983 1009007 TimTec1_000100 CCCC(=O)NCc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E13 compound treatment 2696417.0 1140000.0 1.21 2870557.0 1240000.0 1.14 3010493.0 1559846.96875 1.52824905320341 2.235 0.9914 1705451 TimTec1_000101 CC1C2COCC2CC(C1O)N(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E14 compound treatment 2696828.0 1140000.0 1.21 2831394.0 1200000.0 1.1 3034243.0 1583596.96875 1.55151794799933 2.228 0.989 1074947 TimTec1_000102 Cc1ccc[n+](Cc2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E15 compound treatment 3307711.0 1750000.0 1.86 3716312.0 2090000.0 1.91 3100052.0 1649405.96875 1.61599385105722 3.1082 0.9975 1394494 TimTec1_000103 Nc1ccc(c2nc3cc(Cl)ccc3o2)c(O)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E16 compound treatment 2436287.0 875000.0 0.93 2427917.0 798000.0 0.73 2369791.0 919144.96875 0.900525792843976 1.4788 0.9948 3209733 TimTec1_000104 CN(C)/C=C(\C=[N+](C)C)/c1cc([nH]n1)\C(=C/N(C)C)\C=[N+](C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E17 compound treatment 1258110.0 -303000.0 -0.32 1253775.0 -377000.0 -0.35 1281429.0 -169217.03125 -0.165789191487766 -0.4809 -0.9612 3081522 TimTec1_000105 Oc1ccc(Cl)cc1/N=C/c2ccc(o2)c3ccc(Br)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E18 compound treatment 1841379.0 280000.0 0.3 1979152.0 349000.0 0.32 1986045.0 535398.96875 0.524553359060577 0.6593 0.9658 1633318 TimTec1_000106 Oc1ccc2occ(C(=O)c3ccc(Oc4ccccc4)cc3)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E19 compound treatment 1892280.0 331000.0 0.35 1687532.0 57200.0 0.05 1851643.0 400996.96875 0.392873948603252 0.4602 0.8684 1221609 TimTec1_000107 CCOC(=O)C1(COC(=O)C1)c2csc(N)n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E20 compound treatment 2003442.0 442000.0 0.47 2385478.0 755000.0 0.69 1855661.0 405014.96875 0.396810555731252 0.9 0.972 1365512 TimTec1_000108 CSc1c(CC(=O)NCCc2ccccc2)n(C)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E21 compound treatment 1675110.0 114000.0 0.12 1680172.0 49800.0 0.05 1634371.0 183724.96875 0.180003240809589 0.2002 0.903 3081562 TimTec1_000109 Cc1c(/C=N/c2cccc3nsnc23)c(O)n4c5ccccc5nc4c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E22 compound treatment 1756099.0 195000.0 0.21 1514208.0 -116000.0 -0.11 1480320.0 29673.96875 0.0290728613482618 0.0749 0.3192 1408177 TimTec1_000110 O=C(CCN1CCCCC1)c2cc3ccccc3o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E23 mock treatment 1608610.0 47400.0 0.05 1621112.0 -9230.0 -0.01 1318861.0 -131785.03125 -0.129115453803516 -0.0504 -0.3627 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 E24 mock treatment 1330684.0 -231000.0 -0.24 1356537.0 -274000.0 -0.25 1312987.0 -137659.03125 -0.134870463825884 -0.3642 -0.9693 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F01 compound treatment 1989545.0 428000.0 0.46 2385247.0 755000.0 0.69 2285328.0 834681.96875 0.817773765006169 1.1343 0.9747 1212077 TimTec1_000111 CCOC(=O)c1cc2ccccc2nc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F02 compound treatment 2395219.0 834000.0 0.89 2621041.0 991000.0 0.91 2341477.0 890830.96875 0.872785351275483 1.5398 0.9999 3209734 TimTec1_000112 C=CCNC(=O)CC1CCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F03 compound treatment 2839012.0 1280000.0 1.36 3236243.0 1610000.0 1.47 2854342.0 1403695.96875 1.37526121357066 2.4277 0.9994 3209735 TimTec1_000113 COc1ccc(O)c(c1)c2c[nH]c(=S)nc2c3cc(OC)ccc3OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F04 compound treatment 2727806.0 1170000.0 1.24 2897548.0 1270000.0 1.16 2654768.0 1204121.96875 1.17972999630744 2.0673 0.9996 1743325 TimTec1_000114 COc1ccc2nc3-c4cccc5cccc(-c3nc2c1)c45 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F05 compound treatment 2550431.0 989000.0 1.05 2835186.0 1200000.0 1.1 2742783.0 1292136.96875 1.26596207106378 1.9753 0.9968 2104259 TimTec1_000115 Brc1cccc(c1)c2n[nH]c(=O)[nH]2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F06 compound treatment 2602563.0 1040000.0 1.11 2750821.0 1120000.0 1.03 2699369.0 1248722.96875 1.22342751111978 1.9381 0.9974 1644388 TimTec1_000116 O=S(=O)(CCc1ccncc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F07 compound treatment 2588678.0 1030000.0 1.09 3061264.0 1430000.0 1.31 2736272.0 1285625.96875 1.25958296478942 2.1147 0.9971 1066566 TimTec1_000117 Cc1ccc(cc1)S(=O)(=O)N2CCC(=O)c3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F08 compound treatment 2906417.0 1350000.0 1.43 3278103.0 1650000.0 1.51 3039742.0 1589095.96875 1.55690555441966 2.596 0.9994 1595822 TimTec1_000118 Nc1ccc(cc1)C(=O)NCC2CCCN3CCCCC23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F09 compound treatment 2729084.0 1170000.0 1.24 3220185.0 1590000.0 1.46 2669068.0 1218421.96875 1.19374032033194 2.2469 0.9961 3209736 TimTec1_000119 CN(C)Cc1c(C#N)c2ccccc2n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F10 compound treatment 2832853.0 1270000.0 1.35 3132462.0 1500000.0 1.38 3179523.0 1728876.96875 1.69385500214466 2.5529 0.9945 3081571 TimTec1_000120 Cc1c(O)n(nc1/C=N/n2cnnc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F11 compound treatment 2507301.0 946000.0 1.01 2615395.0 985000.0 0.9 2533004.0 1082357.96875 1.06043257711037 1.7139 0.9978 3209737 TimTec1_000121 Oc1ccc(cc1)n2cccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F12 compound treatment 2890265.0 1330000.0 1.41 3337333.0 1710000.0 1.56 2791529.0 1340882.96875 1.31372062035734 2.4771 0.9974 1378112 TimTec1_000122 CC(C)(C)C(=O)c1sc2nc3CCCc3c(c4cccs4)c2c1N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F13 compound treatment 2536046.0 975000.0 1.04 2984987.0 1350000.0 1.24 2571783.0 1121136.96875 1.09842602853315 1.949 0.9971 1389415 TimTec1_000123 Clc1cccc(OCCN2CCOCC2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F14 compound treatment 2973362.0 1410000.0 1.5 2903240.0 1270000.0 1.17 2892405.0 1441758.96875 1.41255316904927 2.3554 0.9946 3209738 TimTec1_000124 COc1ccc(C/N=C/C2C(=O)N(N=C2C(F)(F)F)c3nc4ccccc4s3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F15 compound treatment 1913662.0 352000.0 0.37 2128483.0 498000.0 0.46 1821378.0 370731.96875 0.363222028561207 0.6895 0.9946 1562364 TimTec1_000125 CN1CCN(CCOc2ccccc2)CC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F16 compound treatment 1951101.0 390000.0 0.41 2479371.0 849000.0 0.78 2123935.0 673288.96875 0.659650112888351 1.0693 0.9712 1380422 TimTec1_000126 Brc1ccccc1OCc2nc3ccccc3[nH]2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F17 compound treatment 2135513.0 574000.0 0.61 2577778.0 947000.0 0.87 2370076.0 919429.96875 0.900805019581528 1.3737 0.9868 1337811 TimTec1_000127 COc1ccc(NC(=O)c2ccc3nc(C)c(C)nc3c2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F18 compound treatment 1999995.0 439000.0 0.47 2485911.0 856000.0 0.78 1768885.0 318238.96875 0.311792382476057 0.9019 0.9355 3209739 TimTec1_000128 O=C(/C=C/C(=O)c1ccccc1)N2c3ccccc3Sc4ccccc24 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F19 compound treatment 782741.0 -778000.0 -0.83 807402.0 -823000.0 -0.75 804920.0 -645726.03125 -0.632645519500811 -1.2783 -0.9941 1683844 TimTec1_000129 CC1(C)CC(C)(c2ccccc2)c3cc(SC#N)ccc3N1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F20 compound treatment 1303252.0 -258000.0 -0.27 1228354.0 -402000.0 -0.37 1083366.0 -367280.03125 -0.359840017170487 -0.5787 -0.992 1442200 TimTec1_000130 CC1CCN(CC(O)COc2c(F)cc(Br)cc2F)CC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F21 compound treatment 1664885.0 104000.0 0.11 2265355.0 635000.0 0.58 1613236.0 162589.96875 0.159296373798566 0.4915 0.8015 1404864 TimTec1_000131 OCCN(CCO)Cc1c(O)ccc2occ(C(=O)c3cccs3)c12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F22 compound treatment 1534483.0 -26700.0 -0.03 1509041.0 -121000.0 -0.11 1440726.0 -9920.03125 -0.00971908056962127 -0.0862 -0.7486 1413355 TimTec1_000132 CSC1=NC2(CCCCC2)NC3=C1CCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F23 mock treatment 1668337.0 107000.0 0.11 1680158.0 49800.0 0.05 1314649.0 -135997.03125 -0.133242131061639 0.0151 0.0836 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 F24 mock treatment 1370400.0 -191000.0 -0.2 1496629.0 -134000.0 -0.12 1282549.0 -168097.03125 -0.164691879396337 -0.2829 -0.9805 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G01 compound treatment 2069366.0 508000.0 0.54 2205303.0 575000.0 0.53 2050275.0 599628.96875 0.587482248018136 0.9552 0.9989 1746897 TimTec1_000133 CC1Cc2ccccc2N1C(=O)c3cccc(n3)C(=O)N4C(C)Cc5ccccc45 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G02 compound treatment 3291151.0 1730000.0 1.84 3422148.0 1790000.0 1.64 3321727.0 1871080.96875 1.83317836701031 3.0678 0.9987 1210571 TimTec1_000134 CCOC(=O)C1(C#N)C(C=C(C(=C1N)C#N)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G03 compound treatment 2260531.0 699000.0 0.74 2364672.0 734000.0 0.67 2259446.0 808799.96875 0.792416058264778 1.2751 0.9978 1738871 TimTec1_000135 O=C(C1CC1(c2ccccc2)c3ccccc3)N4CCCCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G04 compound treatment 2945651.0 1380000.0 1.47 3301308.0 1670000.0 1.53 2743773.0 1293126.96875 1.26693201657317 2.465 0.9969 1495985 TimTec1_000136 CC(C)Cc1cc(c(C#N)c(N)n1)c2cccc(Br)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G05 compound treatment 2174360.0 613000.0 0.65 2144947.0 515000.0 0.47 1874414.0 423767.96875 0.415183675062112 0.8882 0.9812 1728047 TimTec1_000137 CC(C)(C)c1cc(CCC(=O)NCCN)cc(c1O)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G06 compound treatment 3047060.0 1490000.0 1.58 3082106.0 1450000.0 1.33 2946217.0 1495570.96875 1.46527509607067 2.5257 0.9976 1006115 TimTec1_000138 CCN(CC)C1CCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G07 compound treatment 3277511.0 1720000.0 1.82 3365719.0 1740000.0 1.59 3180260.0 1729613.96875 1.69457707269054 2.9495 0.9984 1442213 TimTec1_000139 CN(C)c1nc(Cl)nc(n1)N(CN2C(=O)c3ccccc3C2=O)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G08 compound treatment 3069407.0 1510000.0 1.6 3234620.0 1600000.0 1.47 3197895.0 1747248.96875 1.71185483941585 2.7625 0.9981 1391498 TimTec1_000140 Cc1nc2n(C)c(=O)n(C)c(=O)c2cc1C(=O)NN 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G09 compound treatment 3207680.0 1650000.0 1.75 3471632.0 1840000.0 1.69 3237968.0 1787321.96875 1.7511160782014 2.9954 0.9999 1225682 TimTec1_000141 CC(C)Nc1nc(NC(C)C)nc(n1)N(C)C(=O)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G10 compound treatment 1703939.0 143000.0 0.15 1648347.0 18000.0 0.02 1713839.0 263192.96875 0.257861452668212 0.246 0.8209 1485808 TimTec1_000142 Cc1cccc(C[N+](C)(C)CCC(=O)c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G11 compound treatment 3265386.0 1700000.0 1.81 3742193.0 2110000.0 1.94 3425636.0 1974989.96875 1.93498247603555 3.2801 0.9995 1186157 TimTec1_000143 CC12CCCCC2=NC(N1O)c3ccccc3O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G12 compound treatment 3005348.0 1440000.0 1.53 3560238.0 1930000.0 1.77 3251181.0 1800534.96875 1.76406142165145 2.9256 0.9979 1025931 TimTec1_000144 Cc1ccc(cc1)S(=O)(=O)NCc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G13 compound treatment 3104669.0 1540000.0 1.64 3368917.0 1740000.0 1.59 3152653.0 1702006.96875 1.66752930937976 2.8296 0.9998 1323961 TimTec1_000145 S=C(CC(=S)N1CCOCC1)N2CCOCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G14 compound treatment 3174583.0 1610000.0 1.71 3477238.0 1850000.0 1.69 3231713.0 1781066.96875 1.74498778611936 2.9745 0.9999 3209861 TimTec1_000146 CC(=O)NC1CCCCc2sccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G15 compound treatment 1876973.0 316000.0 0.34 1867049.0 237000.0 0.22 1602679.0 152032.96875 0.148953227593911 0.405 0.9497 1288570 TimTec1_000147 CCCC(CCC)c1nc2ccncc2[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G16 compound treatment 2773240.0 1210000.0 1.29 3312948.0 1680000.0 1.54 3129315.0 1678668.96875 1.64466406867461 2.5834 0.995 3209862 TimTec1_000148 OC1=C(C2C3C(CCCC3=O)Oc4ccccc24)C(=O)CCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G17 compound treatment 2538457.0 977000.0 1.04 2398365.0 768000.0 0.7 2502490.0 1051843.96875 1.03053670107657 1.6009 0.9861 3081632 TimTec1_000149 OC(=O)CCC/N=C(\c1ccc(Cl)cc1)/c2cc(F)ccc2O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G18 compound treatment 2587313.0 1030000.0 1.09 2480522.0 850000.0 0.78 2684218.0 1233571.96875 1.20858342585439 1.7771 0.9848 1713094 TimTec1_000150 CN(C)Cc1c(O)ccc2occ(C(=O)c3cccc(Br)c3)c12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G19 compound treatment 2465888.0 905000.0 0.96 2241588.0 611000.0 0.56 2105110.0 654463.96875 0.641206452065899 1.2486 0.9723 3081667 TimTec1_000151 CCCC1CC(C)(OC1=O)C(=O)C[n+]2cccc(c2)C(=O)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G20 compound treatment 2198481.0 637000.0 0.68 2458076.0 828000.0 0.76 1832097.0 381450.96875 0.373723893121943 1.0447 0.9643 1405391 TimTec1_000152 COc1ccc(OC)c(c1)C(=O)c2coc3ccc(O)cc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G21 compound treatment 1809481.0 248000.0 0.26 2061124.0 431000.0 0.39 1532221.0 81574.96875 0.0799224996136567 0.4264 0.8855 3081670 TimTec1_000153 CC(C)C1(CN2CC/3CN(C1)CC2)\C3=N/N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G22 compound treatment 1597833.0 36600.0 0.04 1692980.0 62600.0 0.06 1520523.0 69876.96875 0.0684614667158591 0.0951 0.9762 1185154 TimTec1_000154 CCOC(=O)Cn1c(C)c(Sc2ccccc2)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G23 mock treatment 1870889.0 310000.0 0.33 2229329.0 599000.0 0.55 1919888.0 469241.96875 0.459736505459996 0.7723 0.9801 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 G24 mock treatment 1688660.0 127000.0 0.14 1813706.0 183000.0 0.17 1252306.0 -198340.03125 -0.194322245093729 0.063 0.217 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H01 compound treatment 1950945.0 390000.0 0.41 2316991.0 687000.0 0.63 2128096.0 677449.96875 0.663726823256596 0.9856 0.9817 1114526 TimTec1_000155 NC(=O)c1ccccc1C(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H02 compound treatment 2490829.0 930000.0 0.99 2817331.0 1190000.0 1.09 2418454.0 967807.96875 0.948203023473616 1.7458 0.9983 3209863 TimTec1_000156 CC(C)c1ccc(cc1)C(C)(C)CO 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H03 compound treatment 2441296.0 880000.0 0.94 2534595.0 904000.0 0.83 2437418.0 986771.96875 0.966782868564557 1.5766 0.9979 1440514 TimTec1_000157 COc1ccccc1OCCN2CCN(CC2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H04 compound treatment 2828733.0 1270000.0 1.35 3187806.0 1560000.0 1.43 2963426.0 1512779.96875 1.48213549230406 2.4574 0.9992 3081674 TimTec1_000158 Cc1c(/C=C/c2ccc(Cl)cc2Cl)c(=O)n(c3ccccc3)n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H05 compound treatment 2966842.0 1410000.0 1.49 3102966.0 1470000.0 1.35 2840707.0 1390060.96875 1.36190241860045 2.4278 0.9989 3209864 TimTec1_000159 COc1ccc(Br)c2OCCOc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H06 compound treatment 2824888.0 1260000.0 1.34 3047179.0 1420000.0 1.3 2685948.0 1235301.96875 1.21027838113847 2.2237 0.9991 3209865 TimTec1_000160 COc1ccc(NC(=O)CC(=O)CSc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H07 compound treatment 1009958.0 -551000.0 -0.59 1080428.0 -550000.0 -0.5 1032944.0 -417702.03125 -0.409240615629433 -0.8655 -0.9897 1282382 TimTec1_000161 CN1CCN(Cc2c(C#N)c3ccccc3n2C)CC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H08 compound treatment 2956343.0 1400000.0 1.48 3198665.0 1570000.0 1.44 3044784.0 1594137.96875 1.56184541831697 2.5875 0.9994 1156260 TimTec1_000162 O=C(CSc1nc2ccccc2o1)Nc3ccccn3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H09 compound treatment 3046488.0 1490000.0 1.58 3613300.0 1980000.0 1.82 3347360.0 1896713.96875 1.85829211775995 3.0333 0.9975 1296268 TimTec1_000163 Cn1c(CN2CCOCC2)c(C#N)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H10 compound treatment 3089308.0 1530000.0 1.62 3203921.0 1570000.0 1.44 3166704.0 1716057.96875 1.68129567741249 2.7408 0.9979 1566355 TimTec1_000164 C1CCC(CC1)Nc2c(nnn2C3CCCCC3)c4ccn[nH]4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H11 compound treatment 2924564.0 1360000.0 1.45 3275930.0 1650000.0 1.51 2998297.0 1547650.96875 1.5163001083221 2.5826 0.9998 3081679 TimTec1_000165 CNC(=O)CCc1cc2ccccc2[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H12 compound treatment 3161822.0 1600000.0 1.7 3586734.0 1960000.0 1.79 3195302.0 1744655.96875 1.7093143659756 3.004 0.9997 1429944 TimTec1_000166 NC(=S)c1cnc2ccccn2c1=N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H13 compound treatment 2397995.0 837000.0 0.89 2602582.0 972000.0 0.89 2394168.0 943521.96875 0.92440898646251 1.5615 0.9998 1210033 TimTec1_000167 O=C(CCN1CCN(CC1)c2ccccc2)Nc3nccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H14 compound treatment 3023444.0 1460000.0 1.55 3354084.0 1720000.0 1.58 2869292.0 1418645.96875 1.38990837050535 2.6116 0.9985 3209866 TimTec1_000168 FC(F)(F)c1[nH]n(c2nc3ccccc3s2)c(=O)c1/C=N/CCN4CCOCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H15 compound treatment 3143611.0 1580000.0 1.68 3224442.0 1590000.0 1.46 2853906.0 1403259.96875 1.37483404564935 2.608 0.9963 3081684 TimTec1_000169 COc1ccc(/C=N/c2oc(C)c(C)c2C#N)c(OC)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H16 compound treatment 2541304.0 980000.0 1.04 3056191.0 1430000.0 1.31 2756857.0 1306210.96875 1.27975097318411 2.0946 0.9952 3209867 TimTec1_000170 C[n+]1c(COc2ccccc2O)sc3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H17 compound treatment 1594900.0 33700.0 0.04 1613465.0 -16900.0 -0.02 1587432.0 136785.96875 0.134015087006399 0.0891 0.6384 1912978 TimTec1_000171 CC(=O)N1c2ccccc2C(C)(CC1(C)C)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H18 compound treatment 2649177.0 1090000.0 1.16 2987889.0 1360000.0 1.24 2225669.0 775022.96875 0.759323281021753 1.8242 0.9805 3081687 TimTec1_000172 Cn1ccnc1C(=O)Oc2ccccc2F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H19 compound treatment 2149885.0 589000.0 0.63 2002821.0 372000.0 0.34 1792262.0 341615.96875 0.334695833155815 0.7515 0.9545 1280653 TimTec1_000173 CC1=CC(C)(C)N(c2ccccc12)S(=O)(=O)c3ccc(C)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H20 compound treatment 1885599.0 324000.0 0.34 2100722.0 470000.0 0.43 2084413.0 633766.96875 0.62092871246206 0.8064 0.9706 3209868 TimTec1_000174 O=c1[nH]c2ccc(/N=C/c3ccc4OCOc4c3)cc2[nH]1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H21 compound treatment 1839700.0 278000.0 0.3 1973395.0 343000.0 0.31 1773829.0 323182.96875 0.316636231565364 0.5352 0.9995 3081729 TimTec1_000175 Nc1no[n+]([O-])c1c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H22 compound treatment 1619785.0 58600.0 0.06 1786988.0 157000.0 0.14 1602722.0 152075.96875 0.148995356540279 0.2048 0.948 3081731 TimTec1_000176 CCOc1ccc2S/C(=C/NC(C)CC)/C(=O)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H23 mock treatment 1801611.0 240000.0 0.26 1753754.0 123000.0 0.11 2058795.0 608148.96875 0.595829657856505 0.5568 0.8461 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 H24 mock treatment 1931404.0 370000.0 0.39 2044397.0 414000.0 0.38 1925309.0 474662.96875 0.465047691931099 0.7147 0.9959 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I01 compound treatment 2237894.0 677000.0 0.72 2428765.0 798000.0 0.73 2222412.0 771765.96875 0.75613225827016 1.2742 0.9998 1160113 TimTec1_000177 Cc1ccccc1OCC(=O)Nc2ccc3nn(nc3c2)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I02 compound treatment 5272089.0 3710000.0 3.94 5430544.0 3800000.0 3.48 5349161.0 3898514.96875 3.81954251234398 6.4926 0.9987 1912584 TimTec1_000178 Nc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I03 compound treatment 2653349.0 1090000.0 1.16 2699944.0 1070000.0 0.98 2656512.0 1205865.96875 1.18143866799267 1.9181 0.9967 3081734 TimTec1_000179 COC(=O)CCC(=O)Nc1nccs1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I04 compound treatment 3270028.0 1710000.0 1.82 3260841.0 1630000.0 1.49 3195167.0 1744520.96875 1.70918210067887 2.8979 0.9968 1175548 TimTec1_000180 CC(=O)Nc1nc(cc(c1C#N)c2ccccc2)C3CC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I05 compound treatment 2968353.0 1410000.0 1.5 2846872.0 1220000.0 1.11 2704207.0 1253560.96875 1.22816750745757 2.2161 0.9923 1060191 TimTec1_000181 S=C1N(CN2CCCCC2)CCN1CN3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I06 compound treatment 2982296.0 1420000.0 1.51 3092172.0 1460000.0 1.34 3032115.0 1581468.96875 1.54943305502562 2.5399 0.9981 3209869 TimTec1_000182 CC[N+](C)(CC)Cc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I07 compound treatment 3069259.0 1510000.0 1.6 3480211.0 1850000.0 1.7 3184963.0 1734316.96875 1.6991848037316 2.885 0.9996 3209870 TimTec1_000183 Cc1cc(NN)nc(SCC(=O)NN)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I08 compound treatment 3219438.0 1660000.0 1.76 3358951.0 1730000.0 1.58 3303405.0 1852758.96875 1.81522751688606 2.98 0.9984 1289525 TimTec1_000184 C[N+]1(CC(O)C[N+]2(C)CCCCC2)CCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I09 compound treatment 3157261.0 1600000.0 1.7 3320206.0 1690000.0 1.55 3171396.0 1720749.96875 1.68589263128123 2.8467 0.9992 1505713 TimTec1_000185 C1=C(N=C2C=Cc3nonc3C12)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I10 compound treatment 3251705.0 1690000.0 1.8 3447900.0 1820000.0 1.67 3325561.0 1874914.96875 1.83693470143758 3.0594 0.9991 1080215 TimTec1_000186 OP(=O)(Nc1ccccc1)Nc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I11 compound treatment 2918773.0 1360000.0 1.44 3293911.0 1660000.0 1.52 2966700.0 1516053.96875 1.48534317068561 2.5707 0.9997 3209871 TimTec1_000187 Cc1c(Br)c(nn1CC(=O)N)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I12 compound treatment 3200071.0 1640000.0 1.74 3305074.0 1670000.0 1.53 3008360.0 1557713.96875 1.526159261515 2.7727 0.9981 1668354 TimTec1_000188 O=C(N1CCCCC1)c2ccccc2C(=O)N3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I13 compound treatment 3272967.0 1710000.0 1.82 3030235.0 1400000.0 1.28 3109633.0 1658986.96875 1.62538076815363 2.7293 0.9903 1230919 TimTec1_000189 CN(C)CCNc1nc(no1)c2noc(NCCN(C)C)n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I14 compound treatment 2749797.0 1190000.0 1.26 3317330.0 1690000.0 1.55 2996927.0 1546280.96875 1.51495786049598 2.4965 0.9962 1641088 TimTec1_000190 C[N+]1(CC(O)CN2CCCC2=O)CCCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I15 compound treatment 1221232.0 -340000.0 -0.36 1236115.0 -394000.0 -0.36 1162559.0 -288087.03125 -0.282251234620027 -0.5801 -0.9939 1479834 TimTec1_000191 CC1(C)CC(CC(C)(C)N1)NC(=O)N2c3ccccc3CCc4ccccc24 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I16 compound treatment 2880597.0 1320000.0 1.4 2690099.0 1060000.0 0.97 2782903.0 1332256.96875 1.30526935776746 2.1238 0.9889 3209872 TimTec1_000192 CCOC(=O)C1(C#N)C(C#N)(C(=O)OCC)C1(C#N)C(=O)OCC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I17 compound treatment 2736942.0 1180000.0 1.25 2561361.0 931000.0 0.85 2746512.0 1295865.96875 1.26961553248248 1.947 0.9858 1350657 TimTec1_000193 COc1ccc2NC(C)(C)c3ssc(=S)c3-c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I18 compound treatment 2534338.0 973000.0 1.03 2454545.0 824000.0 0.76 2685319.0 1234672.96875 1.20966212282998 1.7315 0.9829 1439817 TimTec1_000194 CC(=O)Oc1ccc2occ(C(=O)c3cc4ccccc4o3)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I19 compound treatment 2258417.0 697000.0 0.74 2047247.0 417000.0 0.38 1974612.0 523965.96875 0.513351958041555 0.9447 0.965 1619809 TimTec1_000195 Nc1nc(cc(c1C#N)c2ccccc2Cl)C3CC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I20 compound treatment 1678534.0 117000.0 0.12 2087393.0 457000.0 0.42 1824763.0 374116.96875 0.366538458408962 0.5254 0.9212 1402303 TimTec1_000196 CN(C)CCC(=O)c1coc2ccc(OC(=O)C)cc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I21 compound treatment 1707027.0 146000.0 0.15 1759742.0 129000.0 0.12 1385034.0 -65612.03125 -0.0642829243159147 0.1208 0.5881 3209873 TimTec1_000197 C/C(=N\n1nnnc1Nc2ccccc2)/c3ccccc3Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I22 compound treatment 2323155.0 762000.0 0.81 1518706.0 -112000.0 -0.1 1915301.0 464654.96875 0.455242424599832 0.6712 0.7183 1447918 TimTec1_000198 COC(=O)CCC(=O)c1cc2cc(Br)ccc2o1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I23 mock treatment 2201489.0 640000.0 0.68 1565050.0 -65300.0 -0.06 1616996.0 166349.96875 0.162980207248362 0.4524 0.6442 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 I24 mock treatment 1706021.0 145000.0 0.15 1931119.0 301000.0 0.28 1651188.0 200541.96875 0.196479577810979 0.3614 0.972 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J01 compound treatment 1937817.0 377000.0 0.4 2175643.0 545000.0 0.5 1985080.0 534433.96875 0.523607907124658 0.8219 0.9937 1078582 TimTec1_000199 NC(=O)c1ccc2ccccc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J02 compound treatment 2094892.0 534000.0 0.57 2405362.0 775000.0 0.71 1943770.0 493123.96875 0.483134726323836 1.0164 0.9875 1032512 TimTec1_000200 O=C1N(CNc2ccccc2)C(=O)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J03 compound treatment 2389118.0 828000.0 0.88 2670310.0 1040000.0 0.95 2491648.0 1041001.96875 1.01991432813436 1.647 0.9982 1725358 TimTec1_000201 Cc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J04 compound treatment 2335202.0 774000.0 0.82 2723349.0 1090000.0 1.0 2406545.0 955898.96875 0.936535264815737 1.5939 0.9968 1122981 TimTec1_000202 O=C1NC(=O)c2cc(ccc12)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J05 compound treatment 2351538.0 790000.0 0.84 2938080.0 1310000.0 1.2 2545324.0 1094677.96875 1.07250301011608 1.796 0.9899 1020688 TimTec1_000203 Cc1ccc(NC(=O)CC(=O)Nc2ccc(C)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J06 compound treatment 2591001.0 1030000.0 1.09 2987437.0 1360000.0 1.24 2417316.0 966669.96875 0.947088076009289 1.8966 0.9939 1386865 TimTec1_000204 COC(=O)c1ccc(NC(=O)COc2cccc3ccccc23)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J07 compound treatment 2797771.0 1240000.0 1.31 2865398.0 1240000.0 1.13 2830324.0 1379677.96875 1.35172974766714 2.1925 0.9971 1498066 TimTec1_000205 CC(=O)Nc1c(oc2ccccc12)C(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J08 compound treatment 2475953.0 915000.0 0.97 2610762.0 980000.0 0.9 2537421.0 1086774.96875 1.06476010167094 1.6947 0.9976 1326858 TimTec1_000206 CN1CCc2c(C1)c(nc3[nH]nc(N)c23)N4CCCCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J09 compound treatment 2579722.0 1020000.0 1.08 2995483.0 1370000.0 1.25 2716047.0 1265400.96875 1.23976766385268 2.063 0.9979 1734489 TimTec1_000207 Cn1c(CSCc2ccccc2)c(C#N)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J10 compound treatment 2495274.0 934000.0 0.99 2671254.0 1040000.0 0.95 2608604.0 1157957.96875 1.13450114328181 1.7788 0.9972 3209874 TimTec1_000208 O/N=C\1/C2CN3CC1(Cc4ccccc4)CN(C2)CC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J11 compound treatment 2634372.0 1070000.0 1.14 2869460.0 1240000.0 1.14 2825456.0 1374809.96875 1.34696035904118 2.0917 0.9967 3081797 TimTec1_000209 S(c1ccccn1)c2ncnc3c4ccccc4oc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J12 compound treatment 2840459.0 1280000.0 1.36 3032170.0 1400000.0 1.28 2923485.0 1472838.96875 1.44300357958642 2.3597 0.9989 3209875 TimTec1_000210 CCOC(=O)[C@@]1(C#N)[C@H]([C@@H](N2C=C(C=C[C@H]21)C(=O)N)C(=O)N)c3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J13 compound treatment 2427265.0 866000.0 0.92 2906475.0 1280000.0 1.17 2919010.0 1468363.96875 1.4386192299354 2.0371 0.9842 3081799 TimTec1_000211 C(Sc1ncnc2c3ccccc3oc12)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J14 compound treatment 2585138.0 1020000.0 1.09 2728893.0 1100000.0 1.01 2641413.0 1190766.96875 1.1666455293601 1.883 0.9982 3081800 TimTec1_000212 FC(F)(F)c1[nH]n(c2nc3ccccc3s2)c(=O)c1/C=N/Cc4cccnc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J15 compound treatment 2595978.0 1030000.0 1.1 2656849.0 1030000.0 0.94 2478561.0 1027914.96875 1.0070924322946 1.7594 0.9979 1498770 TimTec1_000213 COc1cc(OC)cc(c1)C(=O)N2CCc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J16 compound treatment 2412286.0 851000.0 0.9 2760316.0 1130000.0 1.04 2467236.0 1016589.96875 0.99599684351297 1.6951 0.9984 1358111 TimTec1_000214 Oc1ccccc1OCC(=O)N2CCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J17 compound treatment 2019012.0 458000.0 0.49 2631401.0 1000000.0 0.92 2302387.0 851740.96875 0.834487199798743 1.2923 0.9701 1091978 TimTec1_000215 CCOC(=O)CN=C(c1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J18 compound treatment 1939825.0 379000.0 0.4 2051544.0 421000.0 0.39 1852321.0 401674.96875 0.393538214315742 0.6823 0.9999 1917358 TimTec1_000216 CN1CCN(CC(O)COCCC2(CC3CC4CC(C3)C2)C4)CC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J19 compound treatment 2325286.0 764000.0 0.81 2596028.0 966000.0 0.88 2334121.0 883474.96875 0.865578362217849 1.4795 0.9993 1066363 TimTec1_000217 COc1ccc2NC(C)(C)C=C(C)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J20 compound treatment 1751283.0 190000.0 0.2 1688252.0 57900.0 0.05 1725279.0 274632.96875 0.269069711887806 0.3026 0.8884 1921867 TimTec1_000218 On1c(nc-2c1CCc3c2no[n+]3[O-])c4ccco4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J21 compound treatment 1528082.0 -33100.0 -0.04 2108837.0 478000.0 0.44 1443508.0 -7138.03125 -0.00699343571394742 0.2288 0.52 3081805 TimTec1_000219 Nc1c(no[n+]1[O-])C(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J22 compound treatment 1611289.0 50100.0 0.05 1648499.0 18200.0 0.02 1347230.0 -103416.03125 -0.101321126373389 -0.0182 -0.1572 1879059 TimTec1_000220 CNC(=O)N(Cc1cccnc1)Cc2ccccc2Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J23 mock treatment 1886608.0 325000.0 0.35 1608934.0 -21400.0 -0.02 1936158.0 485511.96875 0.475676923073876 0.4629 0.7868 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 J24 mock treatment 1593815.0 32600.0 0.03 2096673.0 466000.0 0.43 1487075.0 36428.96875 0.0356910248996913 0.2873 0.6678 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K01 compound treatment 1896731.0 336000.0 0.36 1762934.0 133000.0 0.12 1838966.0 388319.96875 0.380453747368393 0.4956 0.9258 1259801 TimTec1_000221 CS(=O)(=O)c1ccc2nc(NC(=O)C3CCCO3)sc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K02 compound treatment 2538955.0 978000.0 1.04 3930200.0 2300000.0 2.11 2900185.0 1449538.96875 1.42017556911295 2.6367 0.9603 1151146 TimTec1_000222 Nc1c(C#N)c(c2ccccc2)c3CCCCc3c1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K03 compound treatment 1978472.0 417000.0 0.44 1933083.0 303000.0 0.28 1781999.0 331352.96875 0.324640731375161 0.6036 0.9805 1392387 TimTec1_000223 Brc1ccc(o1)C(=O)Nc2ccc3OCOc3c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K04 compound treatment 2320584.0 759000.0 0.81 2280047.0 650000.0 0.6 2384202.0 933555.96875 0.914644868334672 1.3377 0.9856 1275980 TimTec1_000224 Clc1ccc(OCC(=O)NCC=C)c(Cl)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K05 compound treatment 1177470.0 -384000.0 -0.41 1100229.0 -530000.0 -0.49 976639.0 -474007.03125 -0.464405041797196 -0.7841 -0.9974 1285366 TimTec1_000225 Cc1cccc(CN2CCN(Cc3cccc(C)c3O)CC2)c1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K06 compound treatment 2634541.0 1070000.0 1.14 2922436.0 1290000.0 1.18 2808082.0 1357435.96875 1.32993830522289 2.11 0.9978 3081809 TimTec1_000226 Cc1cc(C)nc(SCC(=O)NN)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K07 compound treatment 2680455.0 1120000.0 1.19 3090742.0 1460000.0 1.34 3163506.0 1712859.96875 1.67816245949429 2.4283 0.9895 1584109 TimTec1_000227 NNC(=O)C1CC2CC1CC2C(=O)NN 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K08 compound treatment 2713290.0 1150000.0 1.22 3156199.0 1530000.0 1.4 3300547.0 1849900.96875 1.81242741156704 2.5606 0.9864 1914424 TimTec1_000228 C(=N/C(\N=C\c1ccccc1)c2ccccc2)\c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K09 compound treatment 2862348.0 1300000.0 1.38 3134466.0 1500000.0 1.38 3084593.0 1633946.96875 1.60084800496669 2.5184 0.9975 3081861 TimTec1_000229 COC(=O)c1ccc(NC(=S)NC(=O)N2CCOCC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K10 compound treatment 2407270.0 846000.0 0.9 2888812.0 1260000.0 1.15 2546108.0 1095461.96875 1.07327112858008 1.8046 0.9949 3209999 TimTec1_000230 CC(=O)OC1COC(NC(=S)Oc2ccccc2)C(OC(=O)C)C1OC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K11 compound treatment 3006614.0 1450000.0 1.54 3223395.0 1590000.0 1.46 3321246.0 1870599.96875 1.83270711065676 2.7878 0.995 3081863 TimTec1_000231 CCOC(=O)Cn1nc(cc1C)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K12 compound treatment 2889077.0 1330000.0 1.41 3041394.0 1410000.0 1.29 3123860.0 1673213.96875 1.63931957094359 2.5077 0.9951 3210000 TimTec1_000232 COc1ccc(/C=C/C(=O)OC2CCCCC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K13 compound treatment 1252092.0 -309000.0 -0.33 1263535.0 -367000.0 -0.34 1272892.0 -177754.03125 -0.174153256956093 -0.4843 -0.9662 3081865 TimTec1_000233 c1ccc(cc1)c2cnc3nonc3n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K14 compound treatment 1843353.0 282000.0 0.3 1835512.0 205000.0 0.19 1812348.0 361701.96875 0.354374949824063 0.4862 0.9709 1474168 TimTec1_000234 COc1ccc(CCN(C)C(=S)NN)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K15 compound treatment 3021862.0 1460000.0 1.55 3527244.0 1900000.0 1.74 3305645.0 1854998.96875 1.81742214106892 2.9491 0.9979 1445690 TimTec1_000235 OC(=O)c1cc2cccc(c2cc1O)S(=O)(=O)N3CCCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K16 compound treatment 2402310.0 841000.0 0.89 2539733.0 909000.0 0.83 2478088.0 1027441.96875 1.00662901388456 1.5784 0.9969 1033126 TimTec1_000236 Cc1ccc(cc1)S(=O)(=O)Nc2cccc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K17 compound treatment 2299917.0 739000.0 0.78 2450397.0 820000.0 0.75 2134960.0 684313.96875 0.670451778788352 1.2742 0.9979 1183681 TimTec1_000237 COc1cc(NC(=O)Cc2ccc(F)cc2)cc(c1)S(=O)(=O)c3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K18 compound treatment 2486925.0 926000.0 0.98 2406853.0 777000.0 0.71 2183499.0 732852.96875 0.718007521293583 1.3933 0.9878 1604299 TimTec1_000238 COc1cc2c(NC(=O)C)c(CN(C)C)oc2c(Cl)c1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K19 compound treatment 2388192.0 827000.0 0.88 2272838.0 642000.0 0.59 1905038.0 454391.96875 0.445187322819178 1.1043 0.9622 3210001 TimTec1_000239 NS(=O)(=O)c1ccc(NC=C2C(=O)c3ccccc3C2=O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K20 compound treatment 1981333.0 420000.0 0.45 1859976.0 230000.0 0.21 1924878.0 474231.96875 0.464625422724486 0.6475 0.9552 3081870 TimTec1_000240 CCOC(=O)CSc1c([nH]c2ccccc12)c3cccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K21 compound treatment 1502642.0 -58600.0 -0.06 1511945.0 -118000.0 -0.11 1543556.0 92909.96875 0.0910278858246787 -0.046 -0.2976 3210002 TimTec1_000241 S=c1n(CN(Cc2ccccc2)Cc3ccccc3)nnn1c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K22 compound treatment 1554595.0 -6640.0 -0.01 1585740.0 -44600.0 -0.04 1429596.0 -21050.03125 -0.0206236194781942 -0.0396 -0.8544 1023688 TimTec1_000242 CN(C)CCC(=O)c1ccco1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K23 mock treatment 1886231.0 325000.0 0.35 2306213.0 676000.0 0.62 1716234.0 265587.96875 0.26020793700658 0.7072 0.9362 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 K24 mock treatment 1978028.0 417000.0 0.44 1878780.0 248000.0 0.23 1874450.0 423803.96875 0.415218945807908 0.6269 0.9668 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L01 compound treatment 1648605.0 87400.0 0.09 2152442.0 522000.0 0.48 1756085.0 305438.96875 0.299251672859728 0.5026 0.8788 1264988 TimTec1_000243 COc1cc(N)c(Cl)cc1C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L02 compound treatment 1715039.0 154000.0 0.16 2260025.0 630000.0 0.58 2139196.0 688549.96875 0.674601969877006 0.817 0.9051 1706058 TimTec1_000244 CC(=O)N(CN1C(=O)c2ccccc2C1=O)c3ccccc3C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L03 compound treatment 1784681.0 223000.0 0.24 2127173.0 497000.0 0.46 2020616.0 569969.96875 0.55842405219699 0.7224 0.9522 1357677 TimTec1_000245 CNC(=O)c1cnc2cc(Cl)ccc2c1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L04 compound treatment 2085326.0 524000.0 0.56 2574638.0 944000.0 0.87 2329905.0 879258.96875 0.861447765987971 1.3185 0.9825 1569209 TimTec1_000246 O=S(=O)(NC1c2ccccc2Oc3ccccc13)c4ccc5ccccc5c4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L05 compound treatment 2026190.0 465000.0 0.49 2551222.0 921000.0 0.84 2468950.0 1018303.96875 0.997676122910031 1.3485 0.9653 1015215 TimTec1_000247 COc1ccc(NC(=O)CC(=O)Nc2ccc(OC)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L06 compound treatment 2247393.0 686000.0 0.73 2424910.0 795000.0 0.73 2226927.0 776280.96875 0.760555797638732 1.2805 0.9998 1490465 TimTec1_000248 COc1ccc(SCC(=O)Nc2ccccn2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L07 compound treatment 2654854.0 1090000.0 1.16 2761144.0 1130000.0 1.04 2826893.0 1376246.96875 1.3483682496442 2.0478 0.9942 1204062 TimTec1_000249 CSc1c(CC(=O)NN)n(C)c2ccccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L08 compound treatment 2482330.0 921000.0 0.98 2775284.0 1140000.0 1.05 2624839.0 1174192.96875 1.15040726989283 1.8351 0.9978 1235682 TimTec1_000250 CCc1nc2[nH]nc(N)c2c3CC(C)(C)OCc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L09 compound treatment 2592807.0 1030000.0 1.1 2635026.0 1000000.0 0.92 2698109.0 1247462.96875 1.22219303501692 1.8701 0.9935 3081877 TimTec1_000251 O=C(/C=C/N1CCOCC1)c2cccs2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L10 compound treatment 1259760.0 -301000.0 -0.32 1333677.0 -297000.0 -0.27 1250995.0 -199651.03125 -0.195606688086464 -0.4549 -0.9814 3210003 TimTec1_000252 C[n+]1ccc(/C=C/c2cccs2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L11 compound treatment 1319305.0 -242000.0 -0.26 1539796.0 -90600.0 -0.08 1375621.0 -75025.03125 -0.0735052445986099 -0.2388 -0.8529 1338690 TimTec1_000253 CN(C)Cc1c(O)ccc2occ(C(=O)c3ccc(C)cc3)c12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L12 compound treatment 2898100.0 1340000.0 1.42 3382461.0 1750000.0 1.61 2794244.0 1343597.96875 1.31638062243612 2.5073 0.9966 1654307 TimTec1_000254 CC1(C)Cc2c(C#N)c3nc(cnn3c2CO1)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L13 compound treatment 2382740.0 822000.0 0.87 2887822.0 1260000.0 1.15 2721660.0 1271013.96875 1.24526696096803 1.8883 0.9896 1245793 TimTec1_000255 CCc1oc2ccccc2c1C(=O)c3ccc(OC(=O)C)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L14 compound treatment 2584126.0 1020000.0 1.09 3254733.0 1620000.0 1.49 2584411.0 1133764.96875 1.11079822236401 2.1284 0.989 3081942 TimTec1_000256 CN(C)S(=O)(=O)c1ccc(N/C=C\2/C(=C(C#N)C(=O)N(C)C2=O)C)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L15 compound treatment 1872183.0 311000.0 0.33 2041569.0 411000.0 0.38 1876497.0 425850.96875 0.417224479603582 0.6492 0.9956 1570064 TimTec1_000257 Cc1ccc2nc(Nc3ccccc3)cc(C)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L16 compound treatment 1234503.0 -327000.0 -0.35 1275306.0 -355000.0 -0.33 1222576.0 -228070.03125 -0.223450002663529 -0.5173 -0.9841 1509985 TimTec1_000258 C=CCC1CCCCC1NC2CCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L17 compound treatment 2182347.0 621000.0 0.66 2448148.0 818000.0 0.75 2109505.0 658858.96875 0.645512422281818 1.1865 0.9978 1455868 TimTec1_000259 COc1cccc(NC(=O)c2ccc(OC(=S)N3CCC(C)CC3)cc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L18 compound treatment 2524754.0 964000.0 1.02 2271197.0 641000.0 0.59 2429244.0 978597.96875 0.958774449783005 1.4838 0.9757 3210004 TimTec1_000260 Fc1ccc(/N=C/c2ccc(OC(=O)c3ccco3)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L19 compound treatment 1929684.0 368000.0 0.39 2127547.0 497000.0 0.46 2025593.0 574946.96875 0.563300232803276 0.8143 0.9888 1369950 TimTec1_000261 CCOc1ccc2N(C)C(C)(C)c3ssc(=S)c3-c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L20 compound treatment 1895739.0 335000.0 0.36 2394702.0 764000.0 0.7 1745992.0 295345.96875 0.289363127378666 0.7767 0.9279 3210005 TimTec1_000262 NC(=O)[C@H]1[C@H](c2ccc(F)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L21 compound treatment 1591250.0 30000.0 0.03 1879949.0 250000.0 0.23 1504103.0 53456.96875 0.052374087661163 0.1807 0.7631 1298997 TimTec1_000263 CCOC(=O)c1c(CNc2cccc(c2)C(=O)N)n(C)c3cc(Br)c(OC(=O)C)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L22 compound treatment 1990183.0 429000.0 0.46 1983745.0 353000.0 0.32 1365142.0 -85504.03125 -0.0837719708540399 0.4018 0.7106 1677367 TimTec1_000264 O=C(Nc1c(cnn1c2ccccc2)C(=O)N3CCCCC3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L23 mock treatment 1560252.0 -978.0 0.0 1978795.0 348000.0 0.32 1504624.0 53977.96875 0.0528845337322651 0.2143 0.6621 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 L24 mock treatment 1584178.0 22900.0 0.02 1702693.0 72300.0 0.07 1551256.0 100609.96875 0.0985719064532511 0.1093 0.901 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M01 compound treatment 2490789.0 930000.0 0.99 2568844.0 938000.0 0.86 2274489.0 823842.96875 0.80715433129278 1.5329 0.9963 1321921 TimTec1_000265 OC1(N(C(=O)Nc2ccccc21)c3ccccc3)C(=O)NCC=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M02 compound treatment 2230239.0 669000.0 0.71 2308914.0 679000.0 0.62 2310109.0 859462.96875 0.842052774771968 1.2556 0.9923 3081949 TimTec1_000266 CCC1(C)C/C(=C\C)/C(=C(N)C1(C#N)C#N)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M03 compound treatment 2388637.0 827000.0 0.88 2615278.0 985000.0 0.9 2502172.0 1051525.96875 1.03022514282204 1.6236 0.9975 1666559 TimTec1_000267 COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccco3)cc2)ncn1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M04 compound treatment 1912476.0 351000.0 0.37 1976895.0 347000.0 0.32 1948751.0 498104.96875 0.488014825901878 0.6806 0.9841 1006470 TimTec1_000268 C[N+](C)(Cc1ccccc1)Cc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M05 compound treatment 2682803.0 1120000.0 1.19 2743916.0 1110000.0 1.02 2832880.0 1382233.96875 1.35423397061865 2.0592 0.9935 3210006 TimTec1_000269 O=S(N1CCOCC1)c2nc3ccccc3s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M06 compound treatment 2850543.0 1290000.0 1.37 2915902.0 1290000.0 1.18 2975864.0 1525217.96875 1.49432153497655 2.334 0.9954 3081952 TimTec1_000270 S=C(Nc1ccccc1)N=S(c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M07 compound treatment 2901994.0 1340000.0 1.42 3204658.0 1570000.0 1.44 3128534.0 1677887.96875 1.64389888943943 2.6047 0.9978 1489996 TimTec1_000271 COC1OC2COC(OC2CC1O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M08 compound treatment 953673.0 -608000.0 -0.65 971431.0 -659000.0 -0.6 951470.0 -499176.03125 -0.48906419182324 -1.0038 -0.9935 3210007 TimTec1_000272 O=C(c1ccccc1)c2cc[n+](Cc3ccccn3)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M09 compound treatment 2807672.0 1250000.0 1.32 3063117.0 1430000.0 1.31 2930170.0 1479523.96875 1.44955316113214 2.3597 0.999 3210008 TimTec1_000273 Cc1ccc(/C=C/C(=O)NC(=S)N2CCN(CC2)c3ccc(F)cc3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M10 compound treatment 2827144.0 1270000.0 1.35 3131274.0 1500000.0 1.38 3087573.0 1636926.96875 1.60376763892424 2.4968 0.9968 1433383 TimTec1_000274 CCCOC(=S)NC1OCC(O)C(O)C1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M11 compound treatment 2478715.0 917000.0 0.97 2891953.0 1260000.0 1.16 2663396.0 1212749.96875 1.1881832183832 1.9164 0.9964 1720341 TimTec1_000275 O=C(Nc1ccc(cc1)c2ccccc2)C3CC3c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M12 compound treatment 2448813.0 888000.0 0.94 3044746.0 1410000.0 1.3 2674552.0 1223905.96875 1.19911323060818 1.9852 0.9917 3081955 TimTec1_000276 COc1ccc(/C=C/C(=O)NC(C)(C)C)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M13 compound treatment 2564797.0 1000000.0 1.07 2677426.0 1050000.0 0.96 2774979.0 1324332.96875 1.2975058747206 1.9188 0.992 1475730 TimTec1_000277 CCOC(=O)c1nonc1N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M14 compound treatment 1957604.0 396000.0 0.42 2152940.0 523000.0 0.48 2026500.0 575853.96875 0.564188859648745 0.8454 0.9928 3082017 TimTec1_000278 Clc1ccc(cc1)C2=NN=C(SC2)N3CCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M15 compound treatment 1449381.0 -112000.0 -0.12 1540077.0 -90300.0 -0.08 1425919.0 -24727.03125 -0.0242261342640723 -0.1304 -0.8879 1344248 TimTec1_000279 CCN(CC)CCC(O)(C1CCCCC1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M16 compound treatment 2131300.0 570000.0 0.61 2254732.0 624000.0 0.57 2130205.0 679558.96875 0.665793101114474 1.0645 0.998 1532600 TimTec1_000280 Cc1nc2ccccc2cc1C(=O)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M17 compound treatment 2301612.0 740000.0 0.79 2684546.0 1050000.0 0.97 2634840.0 1184193.96875 1.16020567902352 1.6819 0.9879 3210120 TimTec1_000281 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)NCCN4CCOCC4)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M18 compound treatment 1831536.0 270000.0 0.29 1796058.0 166000.0 0.15 1764049.0 313402.96875 0.307054345624138 0.4308 0.9636 1325986 TimTec1_000282 Cc1ccc(o1)C(=O)c2coc3ccc(O)cc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M19 compound treatment 2138068.0 577000.0 0.61 2261808.0 631000.0 0.58 1847225.0 396578.96875 0.388545444299741 0.9123 0.9829 3210121 TimTec1_000283 OCC(CO)(CO)NC=C1C(=O)c2ccccc2C1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M20 compound treatment 1724598.0 163000.0 0.17 1675070.0 44700.0 0.04 1652705.0 202058.96875 0.197965847849102 0.2382 0.8939 1295715 TimTec1_000284 OC(=O)CCCc1cc2cc(Br)ccc2o1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M21 compound treatment 1880909.0 320000.0 0.34 1806157.0 176000.0 0.16 1279846.0 -170800.03125 -0.167340124559848 0.1925 0.4679 3210122 TimTec1_000285 Brc1ccc(/N=C(\c2ccccc2)/c3ccncc3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M22 compound treatment 1209922.0 -351000.0 -0.37 1187903.0 -442000.0 -0.41 1077426.0 -373220.03125 -0.365659690226814 -0.6608 -0.999 1536799 TimTec1_000286 Clc1cccc(NC(=O)NCCN2CCCCC2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M23 mock treatment 1375286.0 -186000.0 -0.2 1396686.0 -234000.0 -0.21 1257719.0 -192927.03125 -0.189018896566136 -0.3468 -0.9986 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 M24 mock treatment 1257063.0 -304000.0 -0.32 1561247.0 -69100.0 -0.06 1185711.0 -264935.03125 -0.259568226101493 -0.373 -0.8895 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N01 compound treatment 1945243.0 384000.0 0.41 2158964.0 529000.0 0.48 1954829.0 504182.96875 0.493969703483756 0.8005 0.9966 1530149 TimTec1_000287 CCCCN1CCC(CC1)(Nc2ccccc2)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N02 compound treatment 2240050.0 679000.0 0.72 2548667.0 918000.0 0.84 2147233.0 696586.96875 0.682476163875946 1.2964 0.9959 1146434 TimTec1_000288 O=C(COC(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N03 compound treatment 2118354.0 557000.0 0.59 2422691.0 792000.0 0.73 2201776.0 751129.96875 0.735914282985586 1.1859 0.9954 1353615 TimTec1_000289 CCOC(=O)c1c(CN(CC)CC)oc2ccc(OC)cc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N04 compound treatment 2311497.0 750000.0 0.8 2419091.0 789000.0 0.72 2257527.0 806880.96875 0.790535931565267 1.3341 0.999 1022729 TimTec1_000290 O=C1N(C2c3ccccc3Oc4ccccc24)C(=O)c5ccccc15 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N05 compound treatment 2371037.0 810000.0 0.86 2568012.0 938000.0 0.86 2407990.0 957343.96875 0.937950993362268 1.5345 0.9991 3082023 TimTec1_000291 O=C1N(/N=C/c2ccccc2)C(=O)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N06 compound treatment 2070131.0 509000.0 0.54 2300763.0 670000.0 0.61 2147702.0 697055.96875 0.682935663314232 1.0612 0.9955 3210123 TimTec1_000292 O=C(CSc1ccccn1)Nc2ccccn2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N07 compound treatment 2600829.0 1040000.0 1.1 2634235.0 1000000.0 0.92 2572686.0 1122039.96875 1.09931073640686 1.8037 0.9966 3082025 TimTec1_000293 Cc1cc(n[nH]1)c2cc(C)[nH]n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N08 compound treatment 2621363.0 1060000.0 1.13 2642325.0 1010000.0 0.93 2823055.0 1372408.96875 1.34460799624518 1.9622 0.9889 1617345 TimTec1_000294 CN1CCc2c(C1)c(NCCO)nc3[nH]nc(N)c23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N09 compound treatment 2523096.0 962000.0 1.02 2512256.0 882000.0 0.81 2743674.0 1293027.96875 1.26683502202223 1.7882 0.9839 1226159 TimTec1_000295 C(Cc1ccncc1)Nc2ccc(OCc3ccccc3)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N10 compound treatment 2011592.0 450000.0 0.48 2085830.0 455000.0 0.42 2008284.0 557637.96875 0.546341862276008 0.8327 0.9941 3210124 TimTec1_000296 COc1ccc2c(C)nc(N/C(=N/C(=O)C)/N)nc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N11 compound treatment 2717956.0 1160000.0 1.23 2840824.0 1210000.0 1.11 2773707.0 1323060.96875 1.29625964170248 2.0986 0.998 1294429 TimTec1_000297 CC(=O)Nc1c(oc2ccc(Br)cc12)C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N12 compound treatment 2358725.0 797000.0 0.85 2652048.0 1020000.0 0.94 2930018.0 1479371.96875 1.44940424020544 1.8667 0.971 3210125 TimTec1_000298 CC1(C)Cc2c(C#N)c(=S)[nH]c(N3CCOCC3)c2CS1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N13 compound treatment 1942334.0 381000.0 0.4 2307441.0 677000.0 0.62 2147245.0 696598.96875 0.682487920791211 0.9861 0.9789 1155921 TimTec1_000299 N#CC(CCN1CCN(CC1)c2ccccc2)(c3ccccc3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N14 compound treatment 2084194.0 523000.0 0.56 2394346.0 764000.0 0.7 2193583.0 742936.96875 0.727887249088197 1.1453 0.9936 1441186 TimTec1_000300 C1CCC(CC1)c2nnc(o2)c3ccco3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N15 compound treatment 2149908.0 589000.0 0.63 2615260.0 985000.0 0.9 2676553.0 1225906.96875 1.20107369622867 1.5757 0.9682 3210126 TimTec1_000301 CCC(C)C1=NN(C(=O)c2ccccc2)C(O)(C1)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N16 compound treatment 2210780.0 650000.0 0.69 2408022.0 778000.0 0.71 2362176.0 911529.96875 0.8930650503652 1.3256 0.993 3082032 TimTec1_000302 Cc1ccc(cc1)c2ccc(OC(=O)c3ccccc3F)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N17 compound treatment 1734175.0 173000.0 0.18 2363195.0 733000.0 0.67 1927745.0 477098.96875 0.467434345729956 0.7637 0.9107 1424431 TimTec1_000303 CC1=CC(C)(C)N(Cc2ccccc2)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N18 compound treatment 1993735.0 433000.0 0.46 2034494.0 404000.0 0.37 1943081.0 492434.96875 0.48245968343902 0.7577 0.9939 3081117 TimTec1_000304 Fc1ccc(/N=C/c2ccc(OC(=O)c3cccs3)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N19 compound treatment 1826589.0 265000.0 0.28 2485218.0 855000.0 0.78 1574516.0 123869.96875 0.121360727209173 0.6852 0.8143 3210127 TimTec1_000305 CC(C)C(=O)N1c2ccc(C)cc2-c3c(ssc3=S)C1(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N20 compound treatment 1544313.0 -16900.0 -0.02 1632883.0 2540.0 0.0 1536392.0 85745.96875 0.0840090074112899 0.0395 0.4592 3081119 TimTec1_000306 CCOc1cc(/C=C/2\SCOC2=O)ccc1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N21 compound treatment 1703588.0 142000.0 0.15 1826343.0 196000.0 0.18 1492565.0 41918.96875 0.0410698136335696 0.2148 0.9008 1693566 TimTec1_000307 CCOC(=O)c1c(C)n(C)c2ccc(O)c(c12)S(=O)(=O)c3ccc(C)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N22 compound treatment 1775433.0 214000.0 0.23 1505853.0 -124000.0 -0.11 1274967.0 -175679.03125 -0.172120290358134 -0.0338 -0.1101 1465551 TimTec1_000308 Fc1ccc(CC(=O)NC2CCCCC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N23 mock treatment 1361546.0 -200000.0 -0.21 1464837.0 -166000.0 -0.15 1234226.0 -216420.03125 -0.212035997426793 -0.3325 -0.9892 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 N24 mock treatment 1223013.0 -338000.0 -0.36 1362499.0 -268000.0 -0.25 1217107.0 -233539.03125 -0.228808216795693 -0.4813 -0.9789 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O01 compound treatment 2239053.0 678000.0 0.72 2546320.0 916000.0 0.84 2226173.0 775526.96875 0.759817071462895 1.3392 0.998 1586093 TimTec1_000309 OC1(N(C(=O)Nc2ccccc21)c3ccccc3)C(=O)N4CCCCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O02 compound treatment 2700845.0 1140000.0 1.21 2812615.0 1180000.0 1.08 2721439.0 1270792.96875 1.24505043777856 2.0436 0.9983 1502323 TimTec1_000310 Nc1nc2CCCc2c(c1C#N)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O03 compound treatment 2577302.0 1020000.0 1.08 2766796.0 1140000.0 1.04 2456864.0 1006217.96875 0.985834949751989 1.7939 0.9993 3210128 TimTec1_000311 NC(=N)NS(=O)(=O)c1ccc(NC(=S)NC(=O)/C=C/c2ccc(F)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O04 compound treatment 1658374.0 97100.0 0.1 1690066.0 59700.0 0.05 1555456.0 104809.96875 0.102686826796109 0.1505 0.9674 1176923 TimTec1_000312 C[N+](C)(CCC#N)Cc1cccc2ccccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O05 compound treatment 1068592.0 -493000.0 -0.52 1065502.0 -565000.0 -0.52 1045602.0 -405044.03125 -0.396839029510411 -0.8302 -0.9927 3081123 TimTec1_000313 S=C(SN1CCOCC1)N2CCOCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O06 compound treatment 2803604.0 1240000.0 1.32 2907355.0 1280000.0 1.17 2923031.0 1472384.96875 1.44255877629222 2.2708 0.9964 1002693 TimTec1_000314 COC1OC2COC(OC2C(O)C1O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O07 compound treatment 2885926.0 1320000.0 1.41 2969365.0 1340000.0 1.23 2776194.0 1325547.96875 1.29869626239122 2.271 0.9984 1507393 TimTec1_000315 CCCOC(=S)NC1OCC(OC(=O)C)C(OC(=O)C)C1OC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O08 compound treatment 1331945.0 -229000.0 -0.24 1405414.0 -225000.0 -0.21 1361411.0 -89235.03125 -0.0874273917586118 -0.3102 -0.9373 3081125 TimTec1_000316 C(c1ccccc1)c2ccc[n+](Cc3ccccn3)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O09 compound treatment 2590216.0 1030000.0 1.09 2717176.0 1090000.0 1.0 2962193.0 1511546.96875 1.48092746926055 2.0614 0.9849 3210129 TimTec1_000317 Cc1cc(C)n(n1)C(=O)COc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O10 compound treatment 2996592.0 1440000.0 1.53 2906326.0 1280000.0 1.17 2588077.0 1137430.96875 1.11438995997756 2.1992 0.9899 1676440 TimTec1_000318 CC12CCC3C(CC=C4CC(CCC34C)OC5CCCCO5)C2CCC1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O11 compound treatment 2967011.0 1410000.0 1.49 2630873.0 1000000.0 0.92 2852459.0 1401812.96875 1.37341635761694 2.1848 0.9811 1921096 TimTec1_000319 O=C1NC(=O)C2(COC(OC2)c3ccccc3)S1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O12 compound treatment 1791777.0 231000.0 0.24 1912951.0 283000.0 0.26 1917472.0 466825.96875 0.457369446519914 0.555 0.9571 3081128 TimTec1_000320 COc1ccc(/C=C/C(=O)NCc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O13 compound treatment 2639592.0 1080000.0 1.15 2529725.0 899000.0 0.82 2801825.0 1351178.96875 1.32380805365498 1.9018 0.9827 3081129 TimTec1_000321 COc1nonc1NC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O14 compound treatment 1704382.0 143000.0 0.15 1785594.0 155000.0 0.14 1673453.0 222806.96875 0.218293554342819 0.296 0.981 1215803 TimTec1_000322 CN(C)CCSc1nc2ccccc2c(=O)n1c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O15 compound treatment 2393121.0 832000.0 0.88 2588567.0 958000.0 0.88 2555185.0 1104538.96875 1.08216425523535 1.6422 0.995 1134169 TimTec1_000323 COc1ccc(c2nc3nnc(C)n3[nH]2)c(OC)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O16 compound treatment 1182103.0 -379000.0 -0.4 1346314.0 -284000.0 -0.26 1150709.0 -299937.03125 -0.293861188444518 -0.5526 -0.9823 1165035 TimTec1_000324 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4ccc(OC(=O)C)cc14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O17 compound treatment 2159389.0 598000.0 0.64 2491577.0 861000.0 0.79 1971542.0 520895.96875 0.510344147219513 1.1173 0.9847 3210130 TimTec1_000325 CC(=O)Nc1ccc(/N=C/c2ccc(cc2)N3CCOCC3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O18 compound treatment 1965092.0 404000.0 0.43 2046582.0 416000.0 0.38 1929158.0 478511.96875 0.468818722502446 0.7387 0.9965 1656585 TimTec1_000326 OC(=O)C(Cc1ccsc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O19 compound treatment 1792817.0 232000.0 0.25 2074254.0 444000.0 0.41 1841785.0 391138.96875 0.383215642712802 0.5982 0.9796 3081133 TimTec1_000327 CC1(C)CC(=O)C(=CNC(CO)(CO)CO)C(=O)C1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O20 compound treatment 1553600.0 -7630.0 -0.01 1609892.0 -20500.0 -0.02 1373067.0 -77579.03125 -0.0760075080642429 -0.0594 -0.7546 3210131 TimTec1_000328 CCOC(=O)c1c(CNC(C)C)oc2ccc(OC)cc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O21 compound treatment 1379820.0 -181000.0 -0.19 1512049.0 -118000.0 -0.11 1312968.0 -137678.03125 -0.134889078941721 -0.2518 -0.9719 3210132 TimTec1_000329 Cc1ccc(C)c(c1)[C@H]2[C@@H](N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O22 compound treatment 1414669.0 -147000.0 -0.16 1400218.0 -230000.0 -0.21 1263624.0 -187022.03125 -0.183233514512666 -0.3175 -0.9925 1145302 TimTec1_000330 CCOC(=O)c1c(C)n(C2CCCCC2)c3ccc(O)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O23 mock treatment 1309987.0 -251000.0 -0.27 1396719.0 -234000.0 -0.21 1247164.0 -203482.03125 -0.199360083284913 -0.3929 -0.9919 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 O24 mock treatment 1299401.0 -262000.0 -0.28 1376852.0 -253000.0 -0.23 1216186.0 -234460.03125 -0.229710560042305 -0.4274 -0.9959 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P01 compound treatment 1832012.0 271000.0 0.29 2100235.0 470000.0 0.43 2047114.0 596467.96875 0.584385280588667 0.7521 0.9632 1004729 TimTec1_000331 COC(=O)c1ccccc1C(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P02 compound treatment 2146086.0 585000.0 0.62 2405023.0 775000.0 0.71 2024978.0 574331.96875 0.562697690895929 1.0936 0.9954 3210133 TimTec1_000332 O=C(Oc1cc(OC(=O)c2ccco2)cc(OC(=O)c3ccco3)c1)c4ccco4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P03 compound treatment 2005631.0 444000.0 0.47 2337582.0 707000.0 0.65 2323765.0 873118.96875 0.855432144343888 1.1407 0.9729 3081813 TimTec1_000333 CCOC(=O)Cc1c(SC)c2ccccc2n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P04 compound treatment 1776878.0 216000.0 0.23 1778724.0 148000.0 0.14 1650326.0 199679.96875 0.195635039397755 0.3238 0.9794 3081814 TimTec1_000334 CCN(CC)CCOc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P05 compound treatment 2010171.0 449000.0 0.48 2387715.0 757000.0 0.69 2302219.0 851572.96875 0.834322602985028 1.1579 0.9767 3210134 TimTec1_000335 O=C(Cc1ccccc1)c2cccs2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P06 compound treatment 2416847.0 856000.0 0.91 2364474.0 734000.0 0.67 2291646.0 840999.96875 0.823963780893353 1.3891 0.9926 1158366 TimTec1_000336 O=C(Nc1ccccc1)C(=S)N2CCOCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P07 compound treatment 2406304.0 845000.0 0.9 2166676.0 536000.0 0.49 2541308.0 1090661.96875 1.06856836247396 1.4192 0.959 1365315 TimTec1_000337 CCOC(=O)c1c(COC(=O)C)n(C)c2cc(Br)c(OC)cc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P08 compound treatment 2252778.0 692000.0 0.73 2725718.0 1100000.0 1.0 2381249.0 930602.96875 0.911751687436468 1.5303 0.9921 1268733 TimTec1_000338 Nc1c(N2CCN(CC2)c3ccccc3)c4ccccc4oc1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P09 compound treatment 1287926.0 -273000.0 -0.29 1288372.0 -342000.0 -0.31 1263606.0 -187040.03125 -0.183251149885564 -0.4544 -0.9774 1047274 TimTec1_000339 CC(=O)Nc1ccc(OCc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P10 compound treatment 2300486.0 739000.0 0.79 2331149.0 701000.0 0.64 2461104.0 1010457.96875 0.989989059812397 1.3959 0.9847 1459196 TimTec1_000340 CCSc1nnc-2c(OC3(Nc4ccccc42)C(=O)Nc5ccc(Br)cc53)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P11 compound treatment 2233732.0 673000.0 0.71 2135489.0 505000.0 0.46 2369531.0 918884.96875 0.900271059679895 1.1996 0.9681 1347458 TimTec1_000341 CCOC(=O)c1oc2ccccc2c1NC(=O)CCN3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P12 compound treatment 2458214.0 897000.0 0.95 2466736.0 836000.0 0.77 2538484.0 1087837.96875 1.06580156841486 1.6082 0.9913 1693186 TimTec1_000342 Cc1nn2c(=O)c3CCCc3[nH]c2c1c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P13 compound treatment 2121651.0 560000.0 0.6 2371021.0 741000.0 0.68 2443466.0 992819.96875 0.972708353858272 1.2973 0.9775 1228757 TimTec1_000343 CC1(C)CC(=O)c2c(c([nH]c2C1)c3ccccc3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P14 compound treatment 2226401.0 665000.0 0.71 2334561.0 704000.0 0.65 2341306.0 890659.96875 0.872617815232952 1.2845 0.9917 3081883 TimTec1_000344 NCCCc1nc2cc3sc(CCCN)nc3cc2s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P15 compound treatment 2064647.0 503000.0 0.53 2423898.0 794000.0 0.73 2430605.0 979958.96875 0.960107879922679 1.2831 0.9736 1650512 TimTec1_000345 CC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P16 compound treatment 2010317.0 449000.0 0.48 1983679.0 353000.0 0.32 2197066.0 746419.96875 0.731299693743953 0.8847 0.9499 3081885 TimTec1_000346 N#Cc1ccc(C#N)c(c1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P17 compound treatment 2045323.0 484000.0 0.51 2336168.0 706000.0 0.65 2169553.0 718906.96875 0.704344026269418 1.0771 0.9919 3081886 TimTec1_000347 Cc1ccc(cc1)C2=C/C(=C/3\OC(=O)c4ccccc34)/C(=O)O2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P18 compound treatment 1903046.0 342000.0 0.36 2006351.0 376000.0 0.34 1763978.0 313331.96875 0.306984783875485 0.5859 0.9976 3210253 TimTec1_000348 COC(=O)NC(Nc1ccccc1C(F)(F)F)C(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P19 compound treatment 1218159.0 -343000.0 -0.36 1311086.0 -319000.0 -0.29 1270494.0 -180152.03125 -0.176502680523277 -0.4813 -0.9633 1111738 TimTec1_000349 Cc1nc(NC(=N)N)nc2ccccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P20 compound treatment 1833479.0 272000.0 0.29 1593078.0 -37300.0 -0.03 1619397.0 168750.96875 0.165332570044363 0.2428 0.7248 1449841 TimTec1_000350 OC(=O)CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P21 compound treatment 1538511.0 -22700.0 -0.02 1575558.0 -54800.0 -0.05 1472920.0 22273.96875 0.021822763601322 -0.0303 -0.5069 1530469 TimTec1_000351 O=C(CSc1nc2ccccc2s1)NC3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P22 compound treatment 1363974.0 -197000.0 -0.21 1443360.0 -187000.0 -0.17 1278093.0 -172553.03125 -0.169057613931521 -0.3176 -0.9949 1494539 TimTec1_000352 CCCN(CCC)C(=O)c1cnn(c1NC(=O)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P23 mock treatment 1448417.0 -113000.0 -0.12 1467015.0 -163000.0 -0.15 1355522.0 -95124.03125 -0.0931970979250616 -0.2094 -0.9823 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2063 P24 mock treatment 1276811.0 -284000.0 -0.3 1402030.0 -228000.0 -0.21 1249182.0 -201464.03125 -0.197382962034464 -0.4093 -0.9809 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A01 compound treatment 2184447.0 612000.0 0.65 2334481.0 737000.0 0.68 1857652.0 491138.46875 0.481189446718897 1.0435 0.9899 3081276 TimTec1_000705 CN(C)C(=O)c1cc(Cl)ccc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A02 compound treatment 2428936.0 857000.0 0.91 2521189.0 924000.0 0.85 2072374.0 705860.46875 0.691561810018682 1.4137 0.9937 1727664 TimTec1_000706 Cc1cccc(NC(=O)c2cnn(c2NC(=O)c3ccco3)c4ccccc4)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A03 compound treatment 2456400.0 884000.0 0.94 2589419.0 992000.0 0.91 1720927.0 354413.46875 0.347234093414796 1.2679 0.9372 1225534 TimTec1_000707 O=C(CC(c1ccccc1)c2ccccc2)N3CCOCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A04 compound treatment 2124102.0 552000.0 0.59 5049300.0 3450000.0 3.16 1956091.0 589577.46875 0.577634361869033 2.4985 0.7643 3211034 TimTec1_000708 COC(=O)CSc1nc(ccc1C#N)c2cccs2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A05 compound treatment 2769520.0 1200000.0 1.27 2519107.0 922000.0 0.84 1981663.0 615149.46875 0.602688348299404 1.5703 0.9564 1669652 TimTec1_000709 O=C(CSc1nc2ccccc2o1)OCc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A06 compound treatment 3004724.0 1430000.0 1.52 2762810.0 1170000.0 1.07 2292850.0 926336.46875 0.907571614188182 2.0195 0.976 1013954 TimTec1_000710 COC(=O)c1cccc(c1)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A07 compound treatment 3002661.0 1430000.0 1.52 3009499.0 1410000.0 1.29 2207651.0 841137.46875 0.824098495547435 2.1006 0.9726 1089954 TimTec1_000711 OC(=O)c1ccc(Oc2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A08 compound treatment 2537993.0 966000.0 1.03 3045886.0 1450000.0 1.33 2209204.0 842690.46875 0.825620036331354 1.8356 0.9816 1005718 TimTec1_000712 OC(=O)CCC(=O)OCc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A09 compound treatment 2044210.0 472000.0 0.5 2196929.0 600000.0 0.55 1621313.0 254799.46875 0.249637980311599 0.751 0.9569 1474924 TimTec1_000713 CN(C)Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A10 compound treatment 2909596.0 1340000.0 1.42 2393679.0 796000.0 0.73 2266564.0 900050.46875 0.881818091299525 1.751 0.9596 3211035 TimTec1_000714 Oc1cccc(/N=C/c2cc(Br)ccc2O)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A11 compound treatment 2632877.0 1060000.0 1.13 2668882.0 1070000.0 0.98 2130852.0 764338.46875 0.748855217592404 1.6501 0.9869 3081282 TimTec1_000715 Cc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A12 compound treatment 1928576.0 356000.0 0.38 1831207.0 234000.0 0.21 1568025.0 201511.46875 0.197429438590122 0.4564 0.9552 1433969 TimTec1_000716 Cc1cccc(c1)C(=O)NN(c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A13 compound treatment 2993850.0 1420000.0 1.51 2951148.0 1350000.0 1.24 2270456.0 903942.46875 0.88563125081724 2.0998 0.9784 1483255 TimTec1_000717 CC(=O)Nc1cccc2ncccc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A14 compound treatment 2488704.0 916000.0 0.97 2431361.0 834000.0 0.76 1863248.0 496734.46875 0.486672088204285 1.2846 0.9657 1158197 TimTec1_000718 COc1ccc(cc1)C(=O)Nc2ccc(C)c(C)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A15 compound treatment 2879672.0 1310000.0 1.39 2748112.0 1150000.0 1.05 1895791.0 529277.46875 0.518555862660861 1.7104 0.9399 3211036 TimTec1_000719 C/C(=N\n1cnnc1)/CC(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A16 compound treatment 2582872.0 1010000.0 1.07 2560029.0 963000.0 0.88 1825163.0 458649.46875 0.449358578381015 1.3889 0.9508 1075886 TimTec1_000720 FC(F)(F)c1cccc(NS(=O)(=O)c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A17 compound treatment 2557019.0 985000.0 1.05 2622975.0 1030000.0 0.94 2150912.0 784398.46875 0.768508860944244 1.5906 0.9923 1922764 TimTec1_000721 OC(=O)c1cc(/N=C/c2ccccc2O)ccc1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A18 compound treatment 1812871.0 241000.0 0.26 2327513.0 730000.0 0.67 1654671.0 288157.46875 0.282320245263277 0.697 0.9051 1340286 TimTec1_000722 COc1ccc(cc1)S(=O)(=O)Nc2cc(C)cc(C)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A19 compound treatment 2171835.0 599000.0 0.64 2039591.0 442000.0 0.41 1861093.0 494579.46875 0.484560742171224 0.8816 0.9826 1715796 TimTec1_000723 CCOC(=O)c1c(CSc2nc(C)ccc2C#N)oc3ccc(OC(=O)C)cc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A20 compound treatment 2023690.0 451000.0 0.48 1781161.0 184000.0 0.17 1514762.0 148248.46875 0.145245390442115 0.4581 0.8664 3211037 TimTec1_000724 COC(=O)C1=C(N)C(=c2s/c(=C/c3ccccc3)/c(=O)n2C1c4ccccc4)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A21 compound treatment 1560419.0 -11900.0 -0.01 1556071.0 -41100.0 -0.04 1331197.0 -35316.53125 -0.034601122114237 -0.0491 -0.9307 3081301 TimTec1_000725 NC1=C(C#N)[C@@H]([C@H](S1)C(=O)c2ccccc2)c3ccc(Br)c(F)c3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A22 compound treatment 1525436.0 -46900.0 -0.05 1434623.0 -163000.0 -0.15 1591632.0 225118.46875 0.220558230145799 0.0125 0.0463 1561863 TimTec1_000726 O=C(Nc1nc(nc2CCCC(=O)c12)c3ccccc3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A23 mock treatment 1612702.0 40400.0 0.04 1418816.0 -178000.0 -0.16 1342083.0 -24430.53125 -0.0239356404827253 -0.0834 -0.4889 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 A24 mock treatment 1607719.0 35400.0 0.04 1328027.0 -269000.0 -0.25 1230838.0 -135675.53125 -0.132927143706822 -0.1975 -0.6984 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B01 compound treatment 2331783.0 759000.0 0.81 2264192.0 667000.0 0.61 2027039.0 660525.46875 0.647145163889288 1.1925 0.9924 3081303 TimTec1_000727 Cc1cccc[n+]1C2[C@H](C(=C(S)N[C@]2(C)O)C#N)c3cccnc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B02 compound treatment 2619418.0 1050000.0 1.11 2793200.0 1200000.0 1.1 2044072.0 677558.46875 0.663833125365453 1.6585 0.9773 3211038 TimTec1_000728 CC1C(CC(C(=O)O)C1(C)C)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B03 compound treatment 2605245.0 1030000.0 1.1 2842166.0 1240000.0 1.14 2279087.0 912573.46875 0.894087412121812 1.8086 0.9947 3211039 TimTec1_000729 CC1=COC=C(/C=N/Cc2ccccc2)N1c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B04 compound treatment 3554818.0 1980000.0 2.11 3621597.0 2020000.0 1.86 2809593.0 1443079.46875 1.41384691959993 3.1037 0.9875 3081306 TimTec1_000730 O=C(CSC#N)c1cccs1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B05 compound treatment 2592113.0 1020000.0 1.08 2846311.0 1250000.0 1.14 2216302.0 849788.46875 0.832574251710783 1.7673 0.9913 1225786 TimTec1_000731 COc1cccc2c1N(C3CC(C)CCC3C2(C)C)C(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B06 compound treatment 2679435.0 1110000.0 1.18 2624959.0 1030000.0 0.94 1358057.0 -8456.53125 -0.00828522677872311 1.2182 0.8083 1605606 TimTec1_000732 c1ccc(nc1)c2ccc3ccccc3n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B07 compound treatment 2994829.0 1420000.0 1.51 2973975.0 1380000.0 1.26 2448196.0 1081682.46875 1.05977076075522 2.2131 0.9897 1478193 TimTec1_000733 CCC(=O)Nc1ncc2C(=O)CC(C)(C)Cc2n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B08 compound treatment 3205038.0 1630000.0 1.74 3231375.0 1630000.0 1.5 2506275.0 1139761.46875 1.11667325089637 2.5111 0.9849 3081309 TimTec1_000734 COc1ccc(cc1)/C(=N/O)/C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B09 compound treatment 3168305.0 1600000.0 1.7 2778912.0 1180000.0 1.08 2124220.0 757706.46875 0.742357562422444 2.033 0.9479 3211040 TimTec1_000735 CCOC(=O)Cc1n[nH]c(CC(=O)OCC)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B10 compound treatment 7400422.0 5830000.0 6.19 7408453.0 5810000.0 5.33 7380377.0 6013863.46875 5.89204026826864 10.0522 0.9981 3081311 TimTec1_000736 Nc1ccc2nn(nc2c1)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B11 compound treatment 2766436.0 1190000.0 1.27 2854615.0 1260000.0 1.15 2233999.0 867485.46875 0.849912762498296 1.8886 0.9871 1090166 TimTec1_000737 CN(C)c1c(C)n(C)n(c2ccccc2)c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B12 compound treatment 3022500.0 1450000.0 1.54 2954392.0 1360000.0 1.24 2331251.0 964737.46875 0.945194722780105 2.1535 0.9814 3081313 TimTec1_000738 CCOc1ccc(cc1)C(=O)N2CCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B13 compound treatment 2686911.0 1110000.0 1.18 3367071.0 1770000.0 1.62 2236510.0 869996.46875 0.852372897017562 2.1124 0.9682 3211041 TimTec1_000739 COc1cccc(/C=N/n2cnnc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B14 compound treatment 2653365.0 1080000.0 1.15 2729043.0 1130000.0 1.04 2039585.0 673071.46875 0.659437018799167 1.6428 0.9765 3211042 TimTec1_000740 C[N+]1(C/C=C\2/COCO2)CCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B15 compound treatment 2513118.0 941000.0 1.0 3068502.0 1470000.0 1.35 2039985.0 673471.46875 0.659828915974677 1.7366 0.9629 1498488 TimTec1_000741 COc1ccc(CC(=O)NC2CCCCC2)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B16 compound treatment 2835621.0 1260000.0 1.34 2623956.0 1030000.0 0.94 2117569.0 751055.46875 0.735841292136647 1.7432 0.9701 3211043 TimTec1_000742 OC(=O)c1cc(/C=N/n2cnnc2)c3OCOCc3c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B17 compound treatment 2354017.0 782000.0 0.83 2551262.0 954000.0 0.87 1967933.0 601419.46875 0.589236477750014 1.3246 0.9868 3211044 TimTec1_000743 Cc1nc(cs1)C2C(Oc3c(O)c(O)ccc3C2=O)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B18 compound treatment 1371877.0 -200000.0 -0.21 1463972.0 -133000.0 -0.12 1152734.0 -213779.53125 -0.209448986196956 -0.3144 -0.9742 3081317 TimTec1_000744 OC(CN1CC2CC(C1)c3cccc(=O)n3C2)/C=N/n4cnnc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B19 compound treatment 1482274.0 -90100.0 -0.1 1566584.0 -30600.0 -0.03 1408928.0 42414.46875 0.0415552762597329 -0.0475 -0.4393 3081354 TimTec1_000745 C(/C=C\c1ccccc1)N2CCN(Cn3nnc4ccccc34)CC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B20 compound treatment 1805974.0 234000.0 0.25 1855276.0 258000.0 0.24 1993497.0 626983.46875 0.614282626236875 0.6345 0.902 3081321 TimTec1_000746 CC(CN1CC2CC(C1)c3cccc(=O)n3C2)SC(=N)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B21 compound treatment 1962875.0 391000.0 0.42 1914218.0 317000.0 0.29 1836448.0 469934.46875 0.460414977445098 0.6732 0.9834 1281576 TimTec1_000747 CN(C1CCCCC1)S(=O)(=O)c2ccc(NC(=O)C)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B22 compound treatment 2524792.0 952000.0 1.01 3034829.0 1440000.0 1.32 3034366.0 1667852.46875 1.63406667917735 2.2884 0.982 1293326 TimTec1_000748 CC1(C)CC(=O)C2=C(C1)Nc3ccc4ccccc4c3C2c5cccnc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B23 mock treatment 1713107.0 141000.0 0.15 1572520.0 -24700.0 -0.02 1561182.0 194668.46875 0.19072505766008 0.1834 0.7535 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 B24 mock treatment 1313369.0 -259000.0 -0.28 1312345.0 -285000.0 -0.26 1304237.0 -62276.53125 -0.0610149917436285 -0.3448 -0.8975 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C01 compound treatment 2282641.0 710000.0 0.75 2171590.0 574000.0 0.53 1922231.0 555717.46875 0.54446026596209 1.054 0.9858 3081323 TimTec1_000749 CC1CCN(CC1)C(=O)c2cc(Cl)ccc2Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C02 compound treatment 2433246.0 861000.0 0.91 2353424.0 756000.0 0.69 1925172.0 558658.46875 0.547341689945029 1.2443 0.9786 1165155 TimTec1_000750 CCN(CC)C(=O)c1cnn(c1NC(=O)c2ccco2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C03 compound treatment 2419673.0 847000.0 0.9 2536267.0 939000.0 0.86 1984301.0 617787.46875 0.605272910171894 1.3662 0.9865 3081325 TimTec1_000751 CCN(CC)c1ccc(/C=N/O)c(O)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C04 compound treatment 2502735.0 930000.0 0.99 2429734.0 833000.0 0.76 2049167.0 682653.46875 0.668824915638515 1.3975 0.9864 1058529 TimTec1_000752 OC(=O)c1ccccc1N2C(=O)c3ccccc3C2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C05 compound treatment 2471418.0 899000.0 0.96 2514027.0 917000.0 0.84 1942829.0 576315.46875 0.56464101101499 1.3627 0.979 1643767 TimTec1_000753 CSc1nc2ccccc2n1CC(=O)Nc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C06 compound treatment 2583786.0 1010000.0 1.07 2670169.0 1070000.0 0.98 1935026.0 568512.46875 0.556996076863724 1.5098 0.9681 1016928 TimTec1_000754 CC(C)CNC(=O)c1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C07 compound treatment 2452782.0 880000.0 0.94 2728454.0 1130000.0 1.04 1971324.0 604810.46875 0.592558786055402 1.4808 0.9762 3211045 TimTec1_000755 Cc1ccc(C)n1c2ccc(cc2)C(=O)OCC(=O)c3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C08 compound treatment 2561024.0 989000.0 1.05 2660905.0 1060000.0 0.97 2090294.0 723780.46875 0.709118803481541 1.5788 0.9873 1586419 TimTec1_000756 CC1CC2OC(C)(C)OC2C(OC(=O)c3ccccc3)O1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C09 compound treatment 2730986.0 1160000.0 1.23 2747825.0 1150000.0 1.05 2207665.0 841151.46875 0.824112211948578 1.7955 0.9873 1233022 TimTec1_000757 CC(C)CCOc1ccccc1C(=O)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C10 compound treatment 1074243.0 -498000.0 -0.53 1035159.0 -562000.0 -0.52 866490.0 -500023.53125 -0.489894523963852 -0.8858 -0.9995 3081330 TimTec1_000758 Cc1ccc(/N=C/c2cc3ccccc3nc2Cl)cc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C11 compound treatment 2743873.0 1170000.0 1.24 2515308.0 918000.0 0.84 2341678.0 975164.46875 0.955410502402719 1.7562 0.9863 3211046 TimTec1_000759 FC(F)(F)c1cc(no1)c2ccc3ccccc3c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C12 compound treatment 2425119.0 853000.0 0.91 2847738.0 1250000.0 1.15 1957291.0 590777.46875 0.578810053395564 1.519 0.9666 3081332 TimTec1_000760 Cc1cccc(c1)C(=O)N(CC#N)CC#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C13 compound treatment 2634675.0 1060000.0 1.13 2512950.0 916000.0 0.84 1957662.0 591148.46875 0.57917353802585 1.4707 0.9668 3211047 TimTec1_000761 O=C(NN1C(=O)c2ccccc2C1=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C14 compound treatment 2140455.0 568000.0 0.6 2407471.0 810000.0 0.74 1876619.0 510105.46875 0.499772231038655 1.0658 0.9872 1022870 TimTec1_000762 O=C(NCc1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C15 compound treatment 2301992.0 730000.0 0.78 2222410.0 625000.0 0.57 1910289.0 543775.46875 0.532760175787231 1.0861 0.986 3211048 TimTec1_000763 C(=N/c1cccnc1)\c2c[nH]c3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C16 compound treatment 2261929.0 690000.0 0.73 2390144.0 793000.0 0.73 1907694.0 541180.46875 0.530217742861108 1.1488 0.9901 1045873 TimTec1_000764 O=S(=O)(NCCc1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C17 compound treatment 2338446.0 766000.0 0.81 2483501.0 886000.0 0.81 2080269.0 713755.46875 0.699296880520315 1.3427 0.9976 3211049 TimTec1_000765 Cc1c(/N=C/c2cccc(C)c2)c(=O)n(c3ccccc3)n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C18 compound treatment 2180239.0 608000.0 0.65 2142454.0 545000.0 0.5 1616021.0 249507.46875 0.244453180679598 0.8026 0.9415 1634239 TimTec1_000766 O=C(CCCC(=O)Nc1cccc2ccccc12)Nc3cccc4ccccc34 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C19 compound treatment 1272031.0 -300000.0 -0.32 1204627.0 -393000.0 -0.36 990667.0 -375846.53125 -0.368232985055509 -0.6046 -0.9981 3081336 TimTec1_000767 O=C(CSc1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C20 compound treatment 1802712.0 230000.0 0.24 2096217.0 499000.0 0.46 1573482.0 206968.46875 0.202775895807021 0.5224 0.938 1173423 TimTec1_000768 CCOC(=O)C1=C(C(=O)c2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C21 compound treatment 1865639.0 293000.0 0.31 1556012.0 -41200.0 -0.04 1804267.0 437753.46875 0.428885869932359 0.4058 0.7634 1130405 TimTec1_000769 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32CCN(Cc4ccccc4)CC3)N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C22 compound treatment 1701604.0 129000.0 0.14 1543364.0 -53800.0 -0.05 1881935.0 515421.46875 0.504980544501186 0.3424 0.6513 3211050 TimTec1_000770 Cc1cc(c2c(n1)sc3c(=O)[nH]c(C)nc32)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C23 mock treatment 1407109.0 -165000.0 -0.18 1363782.0 -233000.0 -0.21 1388486.0 21972.46875 0.0215273711052811 -0.2124 -0.7654 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 C24 mock treatment 1279562.0 -293000.0 -0.31 1429265.0 -168000.0 -0.15 1307220.0 -59293.53125 -0.0580924185572607 -0.302 -0.8582 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D01 compound treatment 2082114.0 510000.0 0.54 2199587.0 602000.0 0.55 1627416.0 260902.46875 0.255617351466947 0.7791 0.9564 1332544 TimTec1_000771 CCCN1CCC2(CC1)C(C#N)C(=O)NC(=C2C#N)S 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D02 compound treatment 2046651.0 474000.0 0.5 2229351.0 632000.0 0.58 1849973.0 483459.46875 0.473666000692039 0.8989 0.9964 1267101 TimTec1_000772 CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN4CCOCC4)c2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D03 compound treatment 2490233.0 918000.0 0.98 2317796.0 721000.0 0.66 1973033.0 606519.46875 0.59423316673777 1.2875 0.9759 3211051 TimTec1_000773 C(/N=C/C1=CSC=CN1c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D04 compound treatment 2495111.0 923000.0 0.98 2573948.0 977000.0 0.9 1998076.0 631562.46875 0.618768869153529 1.4402 0.9832 1527522 TimTec1_000774 S=c1n(CN2CCCCC2)nc(c3ccccc3)n1c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D05 compound treatment 2463184.0 891000.0 0.95 2706342.0 1110000.0 1.02 1861994.0 495480.46875 0.485443490559061 1.4137 0.9608 1323715 TimTec1_000775 CC1C=C(C)C2C(C)C1COC2c3ccc(OC(=O)NC4CCCCC4)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D06 compound treatment 2347202.0 775000.0 0.82 2173833.0 577000.0 0.53 1763341.0 396827.46875 0.388788910420027 1.005 0.9545 1445377 TimTec1_000776 CC12CCC(C(=O)CO)C2(C)CCC3(C)C4(C)CCC(=O)C=C4CCC13C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D07 compound treatment 2957920.0 1390000.0 1.47 3348965.0 1750000.0 1.61 2664301.0 1297787.46875 1.27149810853933 2.5111 0.9955 3209076 TimTec1_000777 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N(Cc3ccccc3)Cc4ccccc4)c5ccco5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D08 compound treatment 3022715.0 1450000.0 1.54 2660347.0 1060000.0 0.97 2530496.0 1163982.46875 1.14040360461646 2.1108 0.9815 1519326 TimTec1_000778 CCOC(=O)C1=C(CC2=C1CCCC2)NC(=S)Nc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D09 compound treatment 2463464.0 891000.0 0.95 2407802.0 811000.0 0.74 1935115.0 568601.46875 0.557083273985275 1.2973 0.9781 1679838 TimTec1_000779 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D10 compound treatment 3010150.0 1440000.0 1.53 2946104.0 1350000.0 1.24 2051302.0 684788.46875 0.670916666812801 1.9832 0.955 1574797 TimTec1_000780 CCCC(=O)Nc1ccc(N)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D11 compound treatment 3059602.0 1490000.0 1.58 2522619.0 925000.0 0.85 2038892.0 672378.46875 0.658758056942595 1.7825 0.9328 3209077 TimTec1_000781 CCOC(=O)c1c(NC(=O)OC)sc2CCCCc12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D12 compound treatment 2275890.0 704000.0 0.75 2220298.0 623000.0 0.57 1732402.0 365888.46875 0.358476643637247 0.9683 0.9618 1560316 TimTec1_000782 CCOC(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D13 compound treatment 2203162.0 631000.0 0.67 2062072.0 465000.0 0.43 1674565.0 308051.46875 0.30181125128728 0.8072 0.9501 3081341 TimTec1_000783 Nc1nc(nc(n1)C(F)(F)F)N(Cc2ccccc2)Cc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D14 compound treatment 2663366.0 1090000.0 1.16 2471749.0 875000.0 0.8 2282907.0 916393.46875 0.897830030147935 1.6505 0.9876 3209078 TimTec1_000784 Cc1ccoc1CC[N+](C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D15 compound treatment 2183161.0 611000.0 0.65 2441796.0 845000.0 0.77 1781509.0 414995.46875 0.406588880131703 1.0564 0.9701 1672714 TimTec1_000785 COc1ccccc1CC(=O)N(CC=C)CC=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D16 compound treatment 2628423.0 1060000.0 1.12 2373503.0 776000.0 0.71 1740881.0 374367.46875 0.366783884015126 1.2704 0.9216 3209079 TimTec1_000786 C1COc2cccc(/C=N\n3cnnc3)c2OC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D17 compound treatment 2237739.0 665000.0 0.71 2376461.0 779000.0 0.71 1948362.0 581848.46875 0.570061928695236 1.1497 0.995 3209080 TimTec1_000787 CCC(O)c1ccc2c(=O)c(coc2c1)c3ccccc3F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D18 compound treatment 1390286.0 -182000.0 -0.19 1343983.0 -253000.0 -0.23 1135120.0 -231393.53125 -0.22670617832055 -0.3766 -0.9969 3209081 TimTec1_000788 Cc1c(/N=C/C(O)CN2CC3CC(C2)c4cccc(=O)n4C3)c(=O)n(c5ccccc5)n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D19 compound treatment 975689.0 -597000.0 -0.63 996623.0 -601000.0 -0.55 858679.0 -507834.53125 -0.497547296058629 -0.9711 -0.995 3081342 TimTec1_000789 CC(C)Cc1ccc(/C=C/C(=O)N2CCCC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D20 compound treatment 908748.0 -664000.0 -0.71 926656.0 -671000.0 -0.61 921096.0 -445417.53125 -0.436394681049069 -1.0139 -0.9823 3081343 TimTec1_000790 CC(=O)N1CCCCC1c2cccnc2.[O-][N+](=O)O[Ag] 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D21 compound treatment 1843483.0 271000.0 0.29 1991268.0 394000.0 0.36 1418502.0 51988.46875 0.050935335155571 0.4043 0.8698 1588159 TimTec1_000791 CS(=O)(=O)Nc1ccc2CCc3cccc1c32 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D22 compound treatment 2188365.0 616000.0 0.65 1436673.0 -161000.0 -0.15 1373449.0 6935.46875 0.00679497653491167 0.2969 0.4425 1287290 TimTec1_000792 COC(=O)c1c(C)nc(C)c2c(=O)oc3ccccc3c12 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D23 mock treatment 1727368.0 155000.0 0.16 1474629.0 -123000.0 -0.11 1357416.0 -9097.53125 -0.0089132420024783 0.0251 0.1258 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 D24 mock treatment 1388221.0 -184000.0 -0.2 1362251.0 -235000.0 -0.22 1156525.0 -209988.53125 -0.205734780716057 -0.3561 -0.9992 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E01 compound treatment 2051794.0 479000.0 0.51 2225182.0 628000.0 0.58 1726726.0 360212.46875 0.352915622716756 0.8302 0.9816 1535367 TimTec1_000793 CCC(C)c1ccc(NC(=O)c2ccc(cc2)N(CC)CC)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E02 compound treatment 2230914.0 659000.0 0.7 2281415.0 684000.0 0.63 1854345.0 487831.46875 0.477949436820366 1.042 0.9884 1215550 TimTec1_000794 CC(C)(C)C(=O)Nc1ccccc1C(=O)N2CCN(Cc3ccccc3)CC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E03 compound treatment 2432382.0 860000.0 0.91 2544809.0 948000.0 0.87 1991227.0 624713.46875 0.612058609765854 1.3824 0.9864 1689344 TimTec1_000795 Clc1ccc(cc1)C(=O)COC(=O)c2cccc(NC(=O)Cc3ccccc3)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E04 compound treatment 2603497.0 1030000.0 1.1 2794769.0 1200000.0 1.1 2126327.0 759813.46875 0.744421880794444 1.6961 0.9859 3209082 TimTec1_000796 O(c1ccccc1)c2ccc(/C=N/c3ccccc3)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E05 compound treatment 2865997.0 1290000.0 1.37 3021097.0 1420000.0 1.3 2339266.0 972752.46875 0.953047362434392 2.0973 0.9886 3081345 TimTec1_000797 NC(CSCc1oc(cc1C(=O)O)c2ccccc2)C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E06 compound treatment 1323280.0 -249000.0 -0.26 1310041.0 -287000.0 -0.26 1040947.0 -325566.53125 -0.318971510093869 -0.4889 -0.9958 1921518 TimTec1_000798 COc1ccc(NC(=O)/C=C/c2ccccc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E07 compound treatment 2985890.0 1410000.0 1.5 3150930.0 1550000.0 1.42 2328191.0 961677.46875 0.942196709387452 2.2333 0.9821 1601233 TimTec1_000799 OC(=O)C1C(C2CCC1C2)C(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E08 compound treatment 2650368.0 1080000.0 1.15 2700048.0 1100000.0 1.01 2170130.0 803616.46875 0.787337560741634 1.6995 0.9889 3081347 TimTec1_000800 CCOC1(C)OC2CCC(CC)OC2O1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E09 compound treatment 2516088.0 944000.0 1.0 2450731.0 854000.0 0.78 1959628.0 593114.46875 0.581099712643482 1.3661 0.977 3082473 TimTec1_000801 CCc1ccc(cc1)C(=O)CSc2nnc(c3cccc(OC)c3)n2CC=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E10 compound treatment 2831079.0 1260000.0 1.34 2521911.0 925000.0 0.85 2406607.0 1040093.46875 1.01902423167448 1.8499 0.9824 3082474 TimTec1_000802 COc1cc(/N=C/c2cc3cccc(C)c3nc2Cl)c(OC)cc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E11 compound treatment 1479318.0 -93000.0 -0.1 1504661.0 -92500.0 -0.08 1303972.0 -62541.53125 -0.0612746236224041 -0.1414 -0.9824 3209083 TimTec1_000803 CCCC[n+]1cc(nc(n1)N2CCCCC2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E12 compound treatment 2761837.0 1190000.0 1.26 2946585.0 1350000.0 1.24 2299111.0 932597.46875 0.913705784727856 1.9713 0.9904 3209084 TimTec1_000804 O=C(Cc1ccccc1)NC2CCCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E13 compound treatment 2814803.0 1240000.0 1.32 2597106.0 1000000.0 0.92 2109110.0 742596.46875 0.727553646617544 1.7114 0.9701 1914322 TimTec1_000805 Clc1ccc(/N=C/c2c[nH]c3ccccc23)cc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E14 compound treatment 2804275.0 1230000.0 1.31 2617844.0 1020000.0 0.94 2305932.0 939418.46875 0.920388611313245 1.8272 0.9858 1916639 TimTec1_000806 O=C(c1ccccc1)n2cnc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E15 compound treatment 1970644.0 398000.0 0.42 1962218.0 365000.0 0.33 1723286.0 356772.46875 0.349545307007368 0.6393 0.9945 1607222 TimTec1_000807 COc1ccc(cc1)C2(Cc3nc4ccccc4[nH]3)C(=O)c5ccccc5C2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E16 compound treatment 1627506.0 55200.0 0.06 1747448.0 150000.0 0.14 1520818.0 154304.46875 0.15117871367934 0.2006 0.9431 1418431 TimTec1_000808 O=S(=O)(NC(c1ccccc1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E17 compound treatment 2279686.0 707000.0 0.75 2526980.0 930000.0 0.85 1799777.0 433263.46875 0.424486824137256 1.171 0.9654 3082475 TimTec1_000809 Fc1ccc(/C=N/c2ccc(I)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E18 compound treatment 2155303.0 583000.0 0.62 2501283.0 904000.0 0.83 1669260.0 302746.46875 0.296613714997075 1.0073 0.9359 1450437 TimTec1_000810 COC(=O)c1cc(NS(=O)(=O)c2ccccc2)cc(c1)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E19 compound treatment 1658363.0 86000.0 0.09 1893763.0 297000.0 0.27 1735410.0 368896.46875 0.361423710397084 0.4184 0.9068 1573675 TimTec1_000811 O=C(C1c2ccccc2Oc3ccccc13)N4CCCc5ccccc45 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E20 compound treatment 1946668.0 374000.0 0.4 2498411.0 901000.0 0.83 1478421.0 111907.46875 0.109640552304069 0.7698 0.8338 1156098 TimTec1_000812 NC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccc(Br)cc43)C5=C(O1)C(=O)CCC5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E21 compound treatment 1470255.0 -102000.0 -0.11 1515488.0 -81700.0 -0.07 1273468.0 -93045.53125 -0.0911607022268164 -0.1585 -0.9889 1774639 TimTec1_000813 [O-][n+]1onc2c3cc([nH]c3ccc12)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E22 compound treatment 1406341.0 -166000.0 -0.18 1321730.0 -275000.0 -0.25 1137409.0 -229104.53125 -0.224463546733692 -0.3772 -0.9898 1601319 TimTec1_000814 CCOc1ccc(cc1)C2(C)CC(C)(C)Nc3ccccc32 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E23 mock treatment 1357129.0 -215000.0 -0.23 1679726.0 82500.0 0.08 1273304.0 -93209.53125 -0.0913213800687756 -0.1411 -0.5477 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 E24 mock treatment 1401394.0 -171000.0 -0.18 1640924.0 43700.0 0.04 1331993.0 -34520.53125 -0.0338212467349716 -0.1013 -0.5356 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F01 compound treatment 2152437.0 580000.0 0.62 2182387.0 585000.0 0.54 1710589.0 344075.46875 0.337105510913734 0.8602 0.9732 3209085 TimTec1_000815 Oc1n[nH]c(c1C(C(C#N)C#N)c2ccsc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F02 compound treatment 1370164.0 -202000.0 -0.21 1344124.0 -253000.0 -0.23 1113408.0 -253105.53125 -0.247978357007247 -0.4011 -0.9983 1492048 TimTec1_000816 C(C1NCC=N1)c2cccc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F03 compound treatment 1412245.0 -160000.0 -0.17 1460935.0 -136000.0 -0.12 1134108.0 -232405.53125 -0.227697678174591 -0.3018 -0.9721 3209086 TimTec1_000817 O=c/1[nH]c2ccccc2[nH]\c1=N/C(=S)Nc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F04 compound treatment 2677111.0 1100000.0 1.17 2625932.0 1030000.0 0.94 2072163.0 705649.46875 0.6913550842586 1.6213 0.9785 1173360 TimTec1_000818 COc1ccc(cc1OC)C(=O)NC(CO)(CO)CO 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F05 compound treatment 2678637.0 1110000.0 1.18 2585510.0 988000.0 0.91 2023140.0 656626.46875 0.643325146171001 1.5731 0.9725 1399424 TimTec1_000819 C1C2C(Oc3ccccc3C2Oc4ccccc14)c5ccccc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F06 compound treatment 2625639.0 1050000.0 1.12 2492788.0 896000.0 0.82 2018841.0 652327.46875 0.639113231277205 1.4891 0.9745 1110045 TimTec1_000820 CN(C1CCCCC1)S(=O)(=O)c2ccc(N)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F07 compound treatment 3070983.0 1500000.0 1.59 2730708.0 1130000.0 1.04 2560394.0 1193880.46875 1.16969595899997 2.1945 0.983 3209087 TimTec1_000821 CC(C)C1=C2CCCCC2NC(=O)N1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F08 compound treatment 2609127.0 1040000.0 1.1 2624020.0 1030000.0 0.94 1946755.0 580241.46875 0.568487481792624 1.5076 0.9686 1005088 TimTec1_000822 COC(=O)c1cc(C(=O)OC)c(cc1C(=O)OC)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F09 compound treatment 2889994.0 1320000.0 1.4 2581464.0 984000.0 0.9 2542875.0 1176361.46875 1.15253184245556 1.9946 0.9848 1428753 TimTec1_000823 CC(=O)Nc1ccc(cc1)S(=O)(=O)n2cnc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F10 compound treatment 2978797.0 1410000.0 1.49 2689505.0 1090000.0 1.0 2398951.0 1032437.46875 1.01152331973522 2.0249 0.9812 1121309 TimTec1_000824 CCCC(=O)Nc1cccc(N)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F11 compound treatment 1650724.0 78400.0 0.08 1714039.0 117000.0 0.11 1394381.0 27867.46875 0.0273029557293635 0.1257 0.9082 1703558 TimTec1_000825 NC1=C(C#N)C2=CCCCC2C3(C(=O)N(Cc4ccccc4)c5ccccc53)C1(C#N)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F12 compound treatment 2093896.0 522000.0 0.55 2008967.0 412000.0 0.38 1679717.0 313203.46875 0.306858886907852 0.715 0.9697 1304433 TimTec1_000826 CN(C)CC#CC1(O)CCCCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F13 compound treatment 2899288.0 1330000.0 1.41 3019010.0 1420000.0 1.3 2301138.0 934624.46875 0.915691723664754 2.0951 0.9849 3209088 TimTec1_000827 CN(C)c1ccc(/C=C/2\CSC(=S)NC2=O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F14 compound treatment 2520058.0 948000.0 1.01 2865026.0 1270000.0 1.16 2033246.0 666732.46875 0.653226428310268 1.6294 0.9753 3082476 TimTec1_000828 CC/1(OCO\C1=C/C[N+](C)(C)C)C=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F15 compound treatment 2798225.0 1230000.0 1.3 2880461.0 1280000.0 1.18 2140108.0 773594.46875 0.757923718233712 1.8687 0.9775 3209089 TimTec1_000829 COc1ccccc1CC(=O)N2CCCC(C)C2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F16 compound treatment 2694508.0 1120000.0 1.19 2534852.0 938000.0 0.86 2357650.0 991136.46875 0.971058956620844 1.7452 0.9907 3082477 TimTec1_000830 C(=N/n1cnnc1)\c2ccco2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F17 compound treatment 2021426.0 449000.0 0.48 2062915.0 466000.0 0.43 1750416.0 383902.46875 0.376125732936352 0.7391 0.9954 1177709 TimTec1_000831 CCc1cc(c2n[nH]cc2c3nc(C)cs3)c(O)cc1OC(C)C(=O)NN 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F18 compound treatment 1878470.0 306000.0 0.33 1919285.0 322000.0 0.3 1651903.0 285389.46875 0.279608316808746 0.5197 0.998 3082478 TimTec1_000832 Cc1c(/N=C\C2CCCN3CCCCC23)c(=O)n(c4ccccc4)n1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F19 compound treatment 2195881.0 624000.0 0.66 2146879.0 550000.0 0.5 1703071.0 336557.46875 0.329739803500018 0.8638 0.9648 3209090 TimTec1_000833 COc1cc(Br)cc(CNc2cc(C)on2)c1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F20 compound treatment 1546148.0 -26200.0 -0.03 1823022.0 226000.0 0.21 1202246.0 -164267.53125 -0.160939953812296 0.0105 0.0398 3209091 TimTec1_000834 O=C(/C=C/c1ccccc1)N2CCCCC2c3cccnc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F21 compound treatment 1570810.0 -1540.0 0.0 1451984.0 -145000.0 -0.13 1077454.0 -289059.53125 -0.283204034627986 -0.2413 -0.7711 3082479 TimTec1_000835 COc1ccc(NC(=S)SC)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F22 compound treatment 1685557.0 113000.0 0.12 1634659.0 37500.0 0.03 1189300.0 -177213.53125 -0.173623705897685 -0.011 -0.0512 1375719 TimTec1_000836 CCCC1=C(C(NC(=O)N1)c2cc(Br)c(O)c(OC)c2)C(=O)OCC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F23 mock treatment 1555850.0 -16500.0 -0.02 1446037.0 -151000.0 -0.14 1472890.0 106376.46875 0.104221594109701 -0.0299 -0.1718 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 F24 mock treatment 1508267.0 -64100.0 -0.07 1584560.0 -12600.0 -0.01 1105943.0 -260570.53125 -0.255292138045207 -0.1934 -0.7312 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G01 compound treatment 1555980.0 -16400.0 -0.02 1442859.0 -154000.0 -0.14 1275621.0 -90892.53125 -0.0890513156796325 -0.1431 -0.8517 1641121 TimTec1_000837 CCC(C)NC(=O)c1ccc(cc1)N(CC)CC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G02 compound treatment 2983928.0 1410000.0 1.5 2399103.0 802000.0 0.73 2019969.0 653455.46875 0.640218381312144 1.66 0.9279 1504788 TimTec1_000838 Clc1cccc(c1)c2nc3n(ncc3c(=O)o2)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G03 compound treatment 2829803.0 1260000.0 1.34 2799620.0 1200000.0 1.1 2042971.0 676457.46875 0.662754428389861 1.7903 0.9654 1392995 TimTec1_000839 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)NN 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G04 compound treatment 3816966.0 2240000.0 2.39 3835815.0 2240000.0 2.05 2967281.0 1600767.46875 1.56834062412958 3.4671 0.9863 1261047 TimTec1_000840 O=C1NC(C(N1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G05 compound treatment 2986582.0 1410000.0 1.5 3025767.0 1430000.0 1.31 2307296.0 940782.46875 0.921724980681735 2.1557 0.9817 3082481 TimTec1_000841 Sc1nccn1CCc2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G06 compound treatment 2415023.0 843000.0 0.9 2447143.0 850000.0 0.78 2021288.0 654774.46875 0.641510662248389 1.3371 0.9911 1044409 TimTec1_000842 O=C(Nc1ccccc1)C(c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G07 compound treatment 3326146.0 1750000.0 1.86 3252750.0 1660000.0 1.52 2647045.0 1280531.46875 1.25459166438782 2.6763 0.9872 1679314 TimTec1_000843 NC(=O)C1C(C2CCC1C2)C(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G08 compound treatment 3217353.0 1650000.0 1.75 3231884.0 1630000.0 1.5 2483311.0 1116797.46875 1.09417443405033 2.5059 0.9831 3082485 TimTec1_000844 Clc1ccc(/N=C/c2ccc(Br)o2)cc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G09 compound treatment 3107185.0 1530000.0 1.63 3145612.0 1550000.0 1.42 2628301.0 1261787.46875 1.23622736274341 2.4747 0.9937 1181154 TimTec1_000845 O=c1n(c(SCc2ccc3OCOc3c2)nc4ccccc14)c5ccccc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G10 compound treatment 3057861.0 1490000.0 1.58 3272220.0 1680000.0 1.54 2401594.0 1035080.46875 1.0141127803224 2.3832 0.9831 3082487 TimTec1_000846 Cc1ccc(/N=C/c2cc3ccccc3nc2Cl)c(C)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G11 compound treatment 3068910.0 1500000.0 1.59 3559854.0 1960000.0 1.8 2804713.0 1438199.46875 1.4090657740587 2.7702 0.9951 1384410 TimTec1_000847 CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(nc(nn12)N3CCOCC3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G12 compound treatment 3489170.0 1920000.0 2.04 3353110.0 1760000.0 1.61 2608340.0 1241826.46875 1.21667071394251 2.8075 0.9793 1271027 TimTec1_000848 COc1ccc(CC(=O)NCC(C)C)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G13 compound treatment 3149910.0 1580000.0 1.68 3118120.0 1520000.0 1.39 2479155.0 1112641.46875 1.09010262239678 2.402 0.9854 3209212 TimTec1_000849 Cc1ccc(/N=C/c2c[nH]c3ccccc23)nc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G14 compound treatment 3309158.0 1740000.0 1.85 3417764.0 1820000.0 1.67 2574330.0 1207816.46875 1.18334965659475 2.7121 0.9844 1290233 TimTec1_000850 Brc1ccc(cc1)S(=O)(=O)N2CCCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G15 compound treatment 2946250.0 1370000.0 1.46 2988799.0 1390000.0 1.28 2040413.0 673899.46875 0.660248245952473 1.9604 0.9573 3209213 TimTec1_000851 CCCNc1nc(Cl)nc(NCCC)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G16 compound treatment 2749913.0 1180000.0 1.25 2821422.0 1220000.0 1.12 2129903.0 763389.46875 0.747925441543506 1.802 0.9796 1275135 TimTec1_000852 O=S(=O)(N(c1ccccc1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G17 compound treatment 2952457.0 1380000.0 1.47 3006089.0 1410000.0 1.29 2160269.0 793755.46875 0.777676315622367 2.0412 0.9706 3209214 TimTec1_000853 NS(=O)(=O)c1ccc(/N=C/c2c(O)ccc3ccccc23)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G18 compound treatment 2596398.0 1020000.0 1.09 2647928.0 1050000.0 0.96 1921471.0 554957.46875 0.54371566132862 1.4982 0.9656 3082492 TimTec1_000854 COc1ccc(OC)c(NS(=O)(=O)c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G19 compound treatment 1509765.0 -62600.0 -0.07 1118833.0 -478000.0 -0.44 1272545.0 -93968.53125 -0.0920650049593063 -0.3447 -0.7611 3209215 TimTec1_000855 Cc1cc(nn1CC(=O)Nc2sc(C)c(C)c2C(=O)N)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G20 compound treatment 3071071.0 1500000.0 1.59 3000094.0 1400000.0 1.29 2250449.0 883935.46875 0.866029533841155 2.1618 0.9727 1545537 TimTec1_000856 Cc1cc(C)c2oc(nc2c1)c3ccc(NC(=O)COc4ccc(Br)cc4)cc3O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G21 compound treatment 1945698.0 373000.0 0.4 1700699.0 104000.0 0.09 1788435.0 421921.46875 0.413374579725663 0.5225 0.8997 1150900 TimTec1_000857 On1c(nc-2c1CCc3nonc32)c4ccccc4Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G22 compound treatment 2147534.0 575000.0 0.61 1923419.0 326000.0 0.3 1717339.0 350825.46875 0.343718775750469 0.7239 0.9497 3082530 TimTec1_000858 Cc1cc(C)c(C#N)c(SCc2cc(O)[nH]n2)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G23 mock treatment 1526413.0 -45900.0 -0.05 2009001.0 412000.0 0.38 1885618.0 519104.46875 0.508588937744697 0.4833 0.7609 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 G24 mock treatment 1799224.0 227000.0 0.24 1881765.0 285000.0 0.26 1639299.0 272785.46875 0.267259636808418 0.4441 0.9991 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H01 compound treatment 2502659.0 930000.0 0.99 2280502.0 683000.0 0.63 1818295.0 451781.46875 0.442629703877504 1.1879 0.9494 1198410 TimTec1_000859 Cc1[nH]nc(O)c1C2(C(C#N)C#N)C3CC4CC(C3)CC2C4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H02 compound treatment 2736543.0 1160000.0 1.24 2718428.0 1120000.0 1.03 2126057.0 759543.46875 0.744157350200975 1.7372 0.9803 3209216 TimTec1_000860 Cc1ccc(OCc2nnc(S)n2c3ccccc3)cc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H03 compound treatment 2745582.0 1170000.0 1.25 2710105.0 1110000.0 1.02 2048125.0 681611.46875 0.667804023496311 1.6942 0.9716 1739416 TimTec1_000861 CCN(CC)c1[nH]nnc1c2cccc(Cl)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H04 compound treatment 3075293.0 1500000.0 1.6 2998975.0 1400000.0 1.28 2434067.0 1067553.46875 1.04592797277326 2.2677 0.9855 3082533 TimTec1_000862 CCOC(=O)c1ccc(SC)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H05 compound treatment 3083110.0 1510000.0 1.61 3073754.0 1480000.0 1.35 2463708.0 1097194.46875 1.07496853322151 2.3288 0.9873 1302286 TimTec1_000863 O=C(C1CC2CCC1C2)N3CCN(CC3)c4ccc5OCOc5c4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H06 compound treatment 3279596.0 1710000.0 1.81 3485375.0 1890000.0 1.73 2527710.0 1161196.46875 1.13767404078903 2.7033 0.9819 1696584 TimTec1_000864 COc1ccc(cc1)C2OC(=O)c3ccccc3S2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H07 compound treatment 3225044.0 1650000.0 1.76 3150789.0 1550000.0 1.42 2386892.0 1020378.46875 0.999708599636521 2.4132 0.9762 1246999 TimTec1_000865 CC1C=C(C)C2C(C)C1(COC(=O)NC3CCCCC3)COC42CCCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H08 compound treatment 3327596.0 1760000.0 1.87 3533523.0 1940000.0 1.77 2568960.0 1202446.46875 1.17808843701353 2.7816 0.9825 3209217 TimTec1_000866 Sc1nnc(COc2ccccc2)n1CC=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H09 compound treatment 3295183.0 1720000.0 1.83 3599632.0 2000000.0 1.84 2616457.0 1249943.46875 1.22462328737655 2.8235 0.9849 1579810 TimTec1_000867 Clc1ccc(cc1)C(=O)N2CCCc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H10 compound treatment 3503160.0 1930000.0 2.05 3209734.0 1610000.0 1.48 2379105.0 1012591.46875 0.992079341372275 2.6106 0.9611 1114790 TimTec1_000868 Cc1ccc(OCC(=O)O)c(C)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H11 compound treatment 3420986.0 1850000.0 1.96 3150397.0 1550000.0 1.42 2417022.0 1050508.46875 1.02922825438183 2.5502 0.9677 1201078 TimTec1_000869 COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H12 compound treatment 2588007.0 1020000.0 1.08 2598042.0 1000000.0 0.92 2059902.0 693388.46875 0.679342456086272 1.5449 0.9835 1549339 TimTec1_000870 CC(O)(C#CCN1CCOCC1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H13 compound treatment 3552572.0 1980000.0 2.1 3525408.0 1930000.0 1.77 2518778.0 1152264.46875 1.12892297685989 2.8869 0.9718 3209218 TimTec1_000871 Clc1ccccc1/C=C/2\SC3NC(=NN3C2=O)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H14 compound treatment 3433430.0 1860000.0 1.98 3646599.0 2050000.0 1.88 2717274.0 1350760.46875 1.3233980312351 2.9902 0.9864 3082538 TimTec1_000872 CC/1(C)OC(=O)N(\C1=C/C[N+](C)(C)C)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H15 compound treatment 3206094.0 1630000.0 1.74 3129138.0 1530000.0 1.4 2389104.0 1022590.46875 1.00187579101709 2.3913 0.9772 1740713 TimTec1_000873 COc1ccccc1CC(=O)Nc2cccc(NC(=O)C)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H16 compound treatment 1863213.0 291000.0 0.31 1940619.0 343000.0 0.31 1528755.0 162241.46875 0.158954933384403 0.4519 0.9638 1298167 TimTec1_000874 CC(=C1C(=O)NC(=O)NC1=O)c2ccc(N)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H17 compound treatment 2723980.0 1150000.0 1.22 2536269.0 939000.0 0.86 2269963.0 903449.46875 0.885148237548423 1.7145 0.9863 3209219 TimTec1_000875 Fc1ccc(cc1)S(=O)(=O)N(C2CCS(=O)(=O)C2)S(=O)(=O)c3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H18 compound treatment 2963864.0 1390000.0 1.48 2544659.0 947000.0 0.87 2217934.0 851420.46875 0.834173192186865 1.8367 0.9631 1208196 TimTec1_000876 O=C(N1CC2CC(C1)c3cccc(=O)n3C2)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H19 compound treatment 2383628.0 811000.0 0.86 2358312.0 761000.0 0.7 1941371.0 574857.46875 0.563212545810255 1.2256 0.9854 3082542 TimTec1_000877 CC(=O)NCCOc1c(C)cccc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H20 compound treatment 2063690.0 491000.0 0.52 2136455.0 539000.0 0.49 1455940.0 89426.46875 0.0876149512974537 0.6374 0.88 3082544 TimTec1_000878 COc1ccc(OCCSc2nc3ccccc3n2C)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H21 compound treatment 2600441.0 1030000.0 1.09 2054786.0 458000.0 0.42 1288833.0 -77680.53125 -0.0761069519725286 0.8289 0.7069 1488809 TimTec1_000879 CC1CCCCN1S(=O)(=O)c2ccc(NC(=O)C)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H22 compound treatment 1895041.0 323000.0 0.34 2395738.0 799000.0 0.73 2401227.0 1034713.46875 1.01375321466387 1.2058 0.9301 1442845 TimTec1_000880 C(Sc1nc(c(o1)c2ccccc2)c3ccccc3)C4COc5ccccc5O4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H23 mock treatment 2015243.0 443000.0 0.47 2073457.0 476000.0 0.44 1722785.0 356271.46875 0.349054455795042 0.7253 0.9926 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 H24 mock treatment 1835108.0 263000.0 0.28 1647889.0 50700.0 0.05 1806026.0 439512.46875 0.430609237761665 0.4366 0.8473 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I01 compound treatment 1849090.0 277000.0 0.29 1651294.0 54100.0 0.05 1461072.0 94558.46875 0.0926429920592503 0.2519 0.8066 1191196 TimTec1_000881 Cc1ccc(NC(=O)CC(c2ccccc2)c3ccccc3)cc1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I02 compound treatment 2763092.0 1190000.0 1.27 2934978.0 1340000.0 1.23 1888299.0 521785.46875 0.511215628563554 1.7335 0.9449 3082580 TimTec1_000882 O=c1oc(nc2sc3CCCCCc3c12)c4cccnc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I03 compound treatment 3069398.0 1500000.0 1.59 2009169.0 412000.0 0.38 1866971.0 500457.46875 0.490319671165347 1.4196 0.8316 1319708 TimTec1_000883 Cc1cc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCOCC3)no1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I04 compound treatment 3045111.0 1470000.0 1.57 3079439.0 1480000.0 1.36 2326020.0 959506.46875 0.94006968746737 2.2306 0.9802 1427613 TimTec1_000884 Nc1ccc(cc1)C(C2NC(=O)c3ccccc23)c4ccc(N)cc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I05 compound treatment 2910180.0 1340000.0 1.42 2959363.0 1360000.0 1.25 2271506.0 904992.46875 0.886659980902954 2.0534 0.9828 1467312 TimTec1_000885 Cc1ccccc1NC(=O)CCC(=O)OC2CCC(CC2)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I06 compound treatment 2934982.0 1360000.0 1.45 3105710.0 1510000.0 1.38 2194118.0 827604.46875 0.810839634356984 2.1023 0.9733 1018245 TimTec1_000886 CCN(CC)C(=O)C(c1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I07 compound treatment 3307469.0 1740000.0 1.84 3235148.0 1640000.0 1.5 2496529.0 1130015.46875 1.10712467621507 2.5704 0.98 1540337 TimTec1_000887 O=C(C1C(C#N)C2CCC1C2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I08 compound treatment 3441612.0 1870000.0 1.99 3406438.0 1810000.0 1.66 2700225.0 1333711.46875 1.30669439387191 2.8586 0.9862 3082583 TimTec1_000888 OC(=O)c1ccccc1/N=C/c2ccco2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I09 compound treatment 2719825.0 1150000.0 1.22 2851923.0 1250000.0 1.15 2051467.0 684953.46875 0.671078324397699 1.7553 0.9723 3209220 TimTec1_000889 Cn1c(SCc2ccc3OCOc3c2)nnc1c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I10 compound treatment 3013905.0 1440000.0 1.53 3121122.0 1520000.0 1.4 2516218.0 1149704.46875 1.12641483493662 2.3411 0.9923 3082586 TimTec1_000890 COC(=O)Nc1ccc(/N=C/c2cccs2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I11 compound treatment 812492.0 -760000.0 -0.81 845929.0 -751000.0 -0.69 696227.0 -670286.53125 -0.65670849594861 -1.2428 -0.9959 3209221 TimTec1_000891 COc1nncc(n1)c2cnnc(SC)n2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I12 compound treatment 2949030.0 1380000.0 1.46 2773696.0 1180000.0 1.08 2330925.0 964411.46875 0.944875326582064 2.0127 0.9826 1639601 TimTec1_000892 COc1ccc(CC(=O)NN2CCN(CC2)c3ccccc3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I13 compound treatment 3162795.0 1590000.0 1.69 3255586.0 1660000.0 1.52 2371829.0 1005315.46875 0.984950731749744 2.4219 0.9777 3209222 TimTec1_000893 C1CCC(=Nn2cnnc2)CC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I14 compound treatment 2298056.0 726000.0 0.77 2304410.0 707000.0 0.65 1801842.0 435328.46875 0.426509993305828 1.0657 0.9742 1554764 TimTec1_000894 CN1CCN(CC1)S(=O)(=O)c2ccc(Br)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I15 compound treatment 2860331.0 1290000.0 1.37 2694723.0 1100000.0 1.01 2158160.0 791646.46875 0.77561003776449 1.8187 0.974 3209223 TimTec1_000895 CCOc1ccc2nc(/N=C/c3ccccc3O)sc2c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I16 compound treatment 3231732.0 1660000.0 1.76 2843028.0 1250000.0 1.14 2085606.0 719092.46875 0.704525768584561 2.084 0.9406 1340130 TimTec1_000896 CC(=O)Nc1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I17 compound treatment 2598364.0 1030000.0 1.09 2613883.0 1020000.0 0.93 2016741.0 650227.46875 0.637055771105776 1.5352 0.9783 1912630 TimTec1_000897 CCOC(=O)c1ccc(/N=C/c2ccccc2O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I18 compound treatment 2656839.0 1080000.0 1.15 2533132.0 936000.0 0.86 2130785.0 764271.46875 0.748789574815506 1.5929 0.9832 1423694 TimTec1_000898 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I19 compound treatment 2498311.0 926000.0 0.98 2154417.0 557000.0 0.51 1685452.0 318938.46875 0.31247771266173 1.0433 0.9058 3082591 TimTec1_000899 Nc1c(C#N)sc2nc(ccc12)c3ccncc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I20 compound treatment 2237837.0 665000.0 0.71 2244666.0 647000.0 0.59 1784802.0 418288.46875 0.409815173629091 0.9875 0.9777 3209224 TimTec1_000900 CSc1ccc(/N=C/N2C(=O)c3ccccc3C2=O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I21 compound treatment 1973283.0 401000.0 0.43 1952848.0 356000.0 0.33 1514711.0 148197.46875 0.145195423552237 0.518 0.9321 3082593 TimTec1_000901 Oc1[nH]c(=S)[nH]c(=O)c1CN2CCOCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I22 compound treatment 1242189.0 -330000.0 -0.35 1238470.0 -359000.0 -0.33 1164769.0 -201744.53125 -0.197657779928791 -0.5065 -0.9743 3209346 TimTec1_000902 O=C([C@H]1[C@H](c2cccs2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34)c5ccccc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I23 mock treatment 1637149.0 64800.0 0.07 1704759.0 108000.0 0.1 1488679.0 122165.46875 0.11969075537003 0.1658 0.9771 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 I24 mock treatment 1906418.0 334000.0 0.36 1642002.0 44800.0 0.04 1182866.0 -183647.53125 -0.179927371965768 0.1248 0.3119 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J01 compound treatment 2349145.0 777000.0 0.83 2394068.0 797000.0 0.73 2051707.0 685193.46875 0.671313462703005 1.2858 0.9964 1633418 TimTec1_000903 Oc1cc(O)c2sc3nc(ccc3c2n1)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J02 compound treatment 2426875.0 855000.0 0.91 2423158.0 826000.0 0.76 1754765.0 388251.46875 0.380386634977087 1.1809 0.9509 1297117 TimTec1_000904 Nc1ccc(cc1)c2cc3ccccc3o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J03 compound treatment 2747171.0 1170000.0 1.25 2323130.0 726000.0 0.67 2065744.0 699230.46875 0.685066114334599 1.5004 0.9546 3082596 TimTec1_000905 Sc1n[nH]nc1c2cccc(Cl)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J04 compound treatment 2706746.0 1130000.0 1.21 2611466.0 1010000.0 0.93 2146482.0 779968.46875 0.764168599725467 1.6738 0.9827 3209347 TimTec1_000906 CCOC(=O)c1ccc(cc1)S(=O)(=O)N(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J05 compound treatment 2948717.0 1380000.0 1.46 2496490.0 899000.0 0.82 1999830.0 633316.46875 0.620487338268141 1.6785 0.9378 1207815 TimTec1_000907 CC1C=C(C)C2C(C)C1COC2c3ccccc3OCc4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J06 compound treatment 2750872.0 1180000.0 1.25 3071365.0 1470000.0 1.35 2354303.0 987789.46875 0.967779757004761 2.0618 0.9908 1614670 TimTec1_000908 CC1CCCCN1S(=O)(=O)c2ccc(N)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J07 compound treatment 2526879.0 955000.0 1.01 2244865.0 648000.0 0.59 1895690.0 529176.46875 0.518456908624045 1.2277 0.9557 1620705 TimTec1_000909 CC1CC2=C(CC1(CO)CO)C(C)(C)CCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J08 compound treatment 3682304.0 2110000.0 2.24 3815065.0 2220000.0 2.03 2678621.0 1312107.46875 1.2855280274226 3.2102 0.9763 1432678 TimTec1_000910 Nc1cccc(c1)c2nc3ccccc3o2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J09 compound treatment 1744316.0 172000.0 0.18 1698653.0 101000.0 0.09 1253152.0 -113361.53125 -0.111065159770983 0.0951 0.4077 1679574 TimTec1_000911 Brc1ccc(cc1)C(=O)N2CCC(Cc3ccccc3)CC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J10 compound treatment 829371.0 -743000.0 -0.79 863475.0 -734000.0 -0.67 703091.0 -663422.53125 -0.649983540416854 -1.2193 -0.9962 1513995 TimTec1_000912 CCCc1ccc(O)c(N)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J11 compound treatment 3023348.0 1450000.0 1.54 3023563.0 1430000.0 1.31 2254391.0 887877.46875 0.869891680505809 2.1472 0.9757 1491173 TimTec1_000913 CC(=O)OC1CCC2(C)C3CCC4(C)C(CCC4=O)C3CC=C2C1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J12 compound treatment 1792432.0 220000.0 0.23 1792250.0 195000.0 0.18 1323792.0 -42721.53125 -0.0418561185758707 0.2141 0.72 3082639 TimTec1_000914 OC1(CCCCC1)/C=C/CN2CCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J13 compound treatment 2901730.0 1330000.0 1.41 2009960.0 413000.0 0.38 1319512.0 -47001.53125 -0.0460494183538305 1.0074 0.6885 3179906 TimTec1_000915 CC[C@]1(CCCN2CC[C@]3([C@H]4CC1)c5cccc(OC)c5N4C(=O)C)[C@@H]23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J14 compound treatment 2916020.0 1340000.0 1.43 2685169.0 1090000.0 1.0 1985137.0 618623.46875 0.606091975268711 1.75 0.949 3082641 TimTec1_000916 CC1=[N+](CCC#N)c2ccccc2C1(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J15 compound treatment 2884823.0 1310000.0 1.39 2783891.0 1190000.0 1.09 1987876.0 621362.46875 0.608775491178017 1.7846 0.9541 1205123 TimTec1_000917 Cc1cccc(SCC(=O)Nc2ccc3OCCOc3c2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J16 compound treatment 2825324.0 1250000.0 1.33 3063508.0 1470000.0 1.34 2180875.0 814361.46875 0.797864898618778 2.0052 0.9767 3082643 TimTec1_000918 SC(=S)N1CCCCC1c2cccnc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J17 compound treatment 2603501.0 1030000.0 1.1 2628582.0 1030000.0 0.95 2011538.0 645024.46875 0.631958168595326 1.5432 0.9773 3209348 TimTec1_000919 CCOc1ccc(cc1)C(=O)CC(N)C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J18 compound treatment 2493598.0 921000.0 0.98 2181969.0 585000.0 0.54 1990490.0 623976.46875 0.611336539219977 1.2276 0.9647 1146682 TimTec1_000920 O=C1N(CCN2CC3CC(C2)c4cccc(=O)n4C3)C(=O)c5ccccc15 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J19 compound treatment 2046986.0 475000.0 0.5 2149900.0 553000.0 0.51 1378599.0 12085.46875 0.0118406526696063 0.5905 0.8259 1708504 TimTec1_000921 NCCOc1ccc(Cl)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J20 compound treatment 2253607.0 681000.0 0.72 2222312.0 625000.0 0.57 1306357.0 -60156.53125 -0.0589379367134241 0.7147 0.7726 1179648 TimTec1_000922 CN(C)c1ccc(cc1)C2NC(=S)NC(=C2C(=O)OCCc3ccccc3)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J21 compound treatment 2025917.0 454000.0 0.48 1356653.0 -241000.0 -0.22 1414910.0 48396.46875 0.0474160985194888 0.1784 0.3352 3082646 TimTec1_000923 NC(=N)SCc1csc(N)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J22 compound treatment 1920161.0 348000.0 0.37 1581631.0 -15600.0 -0.01 1264058.0 -102455.53125 -0.100380083280695 0.1472 0.3841 3082648 TimTec1_000924 C(Sc1cccc2cccnc12)c3nnc(o3)c4cccs4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J23 mock treatment 1640949.0 68600.0 0.07 1875677.0 278000.0 0.26 1494406.0 127892.46875 0.125301743180398 0.2618 0.8919 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 J24 mock treatment 1437650.0 -135000.0 -0.14 1404993.0 -192000.0 -0.18 1430217.0 63703.46875 0.0624130236833277 -0.1483 -0.63 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K01 compound treatment 1886173.0 314000.0 0.33 1805730.0 209000.0 0.19 1452060.0 85546.46875 0.0838135486950042 0.3513 0.8929 1262368 TimTec1_000925 CC(C)(C)NC(=O)CC(c1ccccc1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K02 compound treatment 2087849.0 515000.0 0.55 2122655.0 525000.0 0.48 1595422.0 228908.46875 0.224271455883759 0.7238 0.9485 1207448 TimTec1_000926 CCc1nc2n(ncc2c(=O)n1CCc3ccccc3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K03 compound treatment 2143713.0 571000.0 0.61 2023920.0 427000.0 0.39 1877534.0 511020.46875 0.500668695827634 0.8654 0.9848 1458877 TimTec1_000927 COc1ccc(cc1S(=O)(=O)Nc2ccc(Cl)cc2)C(=O)Nc3ccc(Cl)cc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K04 compound treatment 2438864.0 867000.0 0.92 2397476.0 800000.0 0.73 1930803.0 564289.46875 0.552858622433274 1.2743 0.9798 3082651 TimTec1_000928 COc1ccc(cc1N)S(=O)(=O)C=C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K05 compound treatment 2307854.0 736000.0 0.78 2426727.0 830000.0 0.76 1702098.0 335584.46875 0.32878651362059 1.08 0.9483 3209349 TimTec1_000929 O=C1CCCC(Cn2cncn2)C1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K06 compound treatment 2451933.0 880000.0 0.93 2342745.0 746000.0 0.68 1807243.0 440729.46875 0.431801584918155 1.1834 0.9577 1111413 TimTec1_000930 O=C(N(c1ccccc1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K07 compound treatment 2948651.0 1380000.0 1.46 2737169.0 1140000.0 1.04 2222548.0 856034.46875 0.838693726106376 1.9318 0.974 3082653 TimTec1_000931 CCC1=CC(NC(=S)N1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K08 compound treatment 3306387.0 1730000.0 1.84 3109901.0 1510000.0 1.39 2191313.0 824799.46875 0.808091455413719 2.3308 0.9539 3209350 TimTec1_000932 Oc1ccccc1/C=N/c2cccc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K09 compound treatment 1200177.0 -372000.0 -0.4 1218655.0 -379000.0 -0.35 936932.0 -429581.53125 -0.420879471870618 -0.6716 -0.9969 3082655 TimTec1_000933 CCc1ccc(OCCNC(=O)c2ccco2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K10 compound treatment 2555947.0 984000.0 1.05 2585745.0 989000.0 0.91 1826500.0 459986.46875 0.450668494690158 1.3867 0.9532 1604140 TimTec1_000934 Clc1ccc(cc1)S(=O)(=O)N2CCc3ccccc23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K11 compound treatment 3146040.0 1570000.0 1.67 3192821.0 1600000.0 1.46 2472846.0 1106332.46875 1.08392142419604 2.4356 0.9853 1651876 TimTec1_000935 CNC(=O)CSc1c([nH]c2ccccc12)c3cccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K12 compound treatment 3089567.0 1520000.0 1.61 3079290.0 1480000.0 1.36 2212002.0 845488.46875 0.828361357074048 2.1933 0.9683 3082657 TimTec1_000936 Cc1onc(c1C(=O)NC2=NCCS2)c3ccccc3Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K13 compound treatment 2920465.0 1350000.0 1.43 3311845.0 1710000.0 1.57 2287925.0 921411.46875 0.902746380214712 2.2555 0.9764 3209351 TimTec1_000937 Clc1ccc(/C=N\n2cnnc2)c(Cl)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K14 compound treatment 2640762.0 1070000.0 1.14 3250272.0 1650000.0 1.51 2563756.0 1197242.46875 1.17298985476014 2.2074 0.9911 1479829 TimTec1_000938 Brc1ccc(cc1)S(=O)(=O)NCC2CCCO2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K15 compound treatment 2454479.0 882000.0 0.94 2847725.0 1250000.0 1.15 1944639.0 578125.46875 0.566414345734174 1.5299 0.9651 3209352 TimTec1_000939 COc1ccc(/C=N/c2ccc(Br)cc2)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K16 compound treatment 2595943.0 1020000.0 1.09 2636498.0 1040000.0 0.95 1825488.0 458974.46875 0.449676994836117 1.4375 0.9494 1308008 TimTec1_000940 CCN(c1ccccc1)S(=O)(=O)c2ccc(C)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K17 compound treatment 2738039.0 1170000.0 1.24 2967047.0 1370000.0 1.26 1948770.0 582256.46875 0.570461663814256 1.7693 0.9545 1918619 TimTec1_000941 CCOC(=O)c1ccc(/N=C/c2ccc(Cl)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K18 compound treatment 2813637.0 1240000.0 1.32 2211897.0 615000.0 0.56 1955265.0 588751.46875 0.576825094201604 1.4198 0.9184 1453153 TimTec1_000942 COC(=O)c1cc(NC(=O)c2ccco2)cc(c1)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K19 compound treatment 3223723.0 1650000.0 1.75 3415506.0 1820000.0 1.67 2452973.0 1086459.46875 1.06445099277375 2.5898 0.9796 3209353 TimTec1_000943 Nc1nc2c3cc4CCCc4nc3sc2c(c1C#N)c5ccc(Br)cc5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K20 compound treatment 1896314.0 324000.0 0.34 2051622.0 454000.0 0.42 1458587.0 92073.46875 0.0902083308563928 0.4913 0.8968 1246610 TimTec1_000944 Cc1cccc(N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4c[nH]c(=O)[nH]c4=O)c1C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K21 compound treatment 2262919.0 691000.0 0.73 1775504.0 178000.0 0.16 1496967.0 130453.46875 0.127810864846602 0.5918 0.7761 1512817 TimTec1_000945 Cc1ccc(cc1)n2c(C)nc3sc4CCCc4c3c2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K22 compound treatment 2477740.0 905000.0 0.96 1907973.0 311000.0 0.28 1826611.0 460097.46875 0.450777246156362 0.9802 0.8911 3209354 TimTec1_000946 NC(=O)C(C(C(C#N)C#N)c1ccccc1Cl)[n+]2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K23 mock treatment 1889670.0 317000.0 0.34 1864468.0 267000.0 0.24 1628475.0 261961.46875 0.25665489923911 0.4843 0.9894 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 K24 mock treatment 1812918.0 241000.0 0.26 1987897.0 391000.0 0.36 1635373.0 268859.46875 0.263413166030785 0.5064 0.9876 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L01 compound treatment 1478062.0 -94300.0 -0.1 1472356.0 -125000.0 -0.11 1156526.0 -209987.53125 -0.205733800973118 -0.2427 -0.9486 1381598 TimTec1_000947 NC(=O)c1c(c(C#N)c(N)[nH]c1=S)c2cccc(Br)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L02 compound treatment 2179683.0 607000.0 0.65 1826483.0 229000.0 0.21 1554035.0 187521.46875 0.183722834876651 0.6 0.8533 1609999 TimTec1_000948 COC(=O)C1CCCN1S(=O)(=O)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L03 compound treatment 2231144.0 659000.0 0.7 2266679.0 669000.0 0.61 1509112.0 142598.46875 0.139709842838032 0.8391 0.8914 1730347 TimTec1_000949 Cc1cccc(c1)C(=O)Nc2ccc3[nH]c(O)nc3c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L04 compound treatment 2327631.0 755000.0 0.8 2546156.0 949000.0 0.87 1760600.0 394086.46875 0.386103435024843 1.1884 0.9547 1111506 TimTec1_000950 OC(=O)CCc1ccc(F)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L05 compound treatment 2552969.0 981000.0 1.04 2580095.0 983000.0 0.9 1728706.0 362192.46875 0.354855513735532 1.3266 0.9326 3209355 TimTec1_000951 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCCc4ccccc34)c5cccs5 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L06 compound treatment 2665534.0 1090000.0 1.16 2717291.0 1120000.0 1.03 1787925.0 421411.46875 0.412874910826887 1.5017 0.9361 1321261 TimTec1_000952 CC(CO)(CO)NS(=O)(=O)c1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L07 compound treatment 2692084.0 1120000.0 1.19 2949768.0 1350000.0 1.24 2003945.0 637431.46875 0.624518980461203 1.7632 0.9644 3209356 TimTec1_000953 CCOC(=O)C1=C(N)n2c(=O)/c(=C\c3ccco3)/sc2=C(C1c4ccco4)C(=O)OCC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L08 compound treatment 7514006.0 5940000.0 6.31 7514069.0 5920000.0 5.42 7479604.0 6113090.46875 5.98925722085453 10.2339 0.9981 1024363 TimTec1_000954 Nc1ccc(cc1)c2nc3ccccc3s2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L09 compound treatment 2643941.0 1070000.0 1.14 2908466.0 1310000.0 1.2 2088341.0 721827.46875 0.707205365522113 1.7596 0.9774 1663099 TimTec1_000955 CCN(C(=O)c1cccc(c1)C(=O)N(CC)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L10 compound treatment 2822368.0 1250000.0 1.33 3054200.0 1460000.0 1.34 2190098.0 823584.46875 0.806901067743106 2.0037 0.9779 1061459 TimTec1_000956 CN(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L11 compound treatment 2940614.0 1370000.0 1.45 3025780.0 1430000.0 1.31 2163464.0 796950.46875 0.780806594311756 2.0461 0.9713 1730887 TimTec1_000957 CCOC(=O)c1csc(N)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L12 compound treatment 2440179.0 868000.0 0.92 2555822.0 959000.0 0.88 1808189.0 441675.46875 0.432728421738237 1.2895 0.9586 1709522 TimTec1_000958 O=C(OC1(CCCCC1)C#CCN2CCCCC2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L13 compound treatment 2019341.0 447000.0 0.48 1887416.0 290000.0 0.27 1623121.0 256607.46875 0.251409355544905 0.573 0.9555 1685514 TimTec1_000959 CCC1(CCCN2CCC3(C4CC1)c5ccc(OC)c(O)c5N4C(=O)C)C23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L14 compound treatment 2652703.0 1080000.0 1.15 2813477.0 1220000.0 1.11 2256663.0 890149.46875 0.872117656462707 1.8099 0.9931 1920479 TimTec1_000960 Oc1ccc(/C=N/c2nccs2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L15 compound treatment 2938457.0 1370000.0 1.45 3026439.0 1430000.0 1.31 2017147.0 650633.46875 0.637453546738919 1.9624 0.9542 3082723 TimTec1_000961 CC(C)Cn1c(SCC(=O)c2ccc(Cl)cc2)nc3ccccc3c1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L16 compound treatment 2763237.0 1190000.0 1.27 2537111.0 940000.0 0.86 1870919.0 504405.46875 0.494187696287633 1.5133 0.9407 3209357 TimTec1_000962 Oc1ccc(/C=N/CC2CCCN3CCCCC23)c(O)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L17 compound treatment 2898157.0 1330000.0 1.41 2569575.0 972000.0 0.89 2076821.0 710307.46875 0.695918726867417 1.7297 0.9575 3082725 TimTec1_000963 OC(=O)C(CC(=O)c1ccc(Cl)cc1)NC2CC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L18 compound treatment 2656440.0 1080000.0 1.15 2605013.0 1010000.0 0.92 1759253.0 392739.46875 0.384783721286312 1.4205 0.931 1466736 TimTec1_000964 O=C1N(CCN2CCCCC2)C(=O)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L19 compound treatment 2430638.0 858000.0 0.91 2193623.0 596000.0 0.55 1578628.0 212114.46875 0.20781765296996 0.9621 0.888 3082726 TimTec1_000965 CC(=O)NCCOc1ccccc1Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L20 compound treatment 2379644.0 807000.0 0.86 2119771.0 523000.0 0.48 1499320.0 132806.46875 0.130116199981541 0.8469 0.8545 3209478 TimTec1_000966 COC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(OC)c(Br)c2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L21 compound treatment 2163864.0 592000.0 0.63 1857335.0 260000.0 0.24 1345122.0 -21391.53125 -0.0209582016917861 0.4885 0.7262 3082728 TimTec1_000967 COc1cccc(c1)c2csc3[nH]cnc(=O)c23 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L22 compound treatment 1533866.0 -38500.0 -0.04 1519854.0 -77300.0 -0.07 1316011.0 -50502.53125 -0.049479498382484 -0.0931 -0.9736 1136019 TimTec1_000968 CN(C)c1ccc(cc1)C2NCC(CSc3nc4ccccc4s3)O2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L23 mock treatment 1816290.0 244000.0 0.26 1833580.0 236000.0 0.22 1471827.0 105313.46875 0.103180127365782 0.3343 0.9464 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 L24 mock treatment 1617875.0 45500.0 0.05 2022684.0 425000.0 0.39 1265824.0 -100689.53125 -0.0986498572508175 0.1961 0.4841 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M01 compound treatment 2053590.0 481000.0 0.51 2114339.0 517000.0 0.47 1541490.0 174976.46875 0.17143195970971 0.6679 0.9302 1453808 TimTec1_000969 O=C(CC(c1ccccc1)c2ccccc2)NC3CCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M02 compound treatment 4571217.0 3000000.0 3.19 4614213.0 3020000.0 2.76 3419386.0 2052872.46875 2.01128730546475 4.5974 0.9836 1706729 TimTec1_000970 Cc1csc(NC(=O)CSc2nc(ccc2C#N)C3(CC4CC5CC(C4)C3)C5)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M03 compound treatment 2630265.0 1060000.0 1.12 2720702.0 1120000.0 1.03 1945707.0 579193.46875 0.567460711192787 1.5711 0.9659 1282202 TimTec1_000971 CC1CN(CC(C)O1)S(=O)(=O)c2cccc(c2)C(=O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M04 compound treatment 2602278.0 1030000.0 1.09 2668484.0 1070000.0 0.98 2093491.0 726977.46875 0.712251041656807 1.6099 0.9854 3082794 TimTec1_000972 Nc1ccc(Cc2ccc(N)c(C#N)c2)cc1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M05 compound treatment 2766125.0 1190000.0 1.27 2774474.0 1180000.0 1.08 2108344.0 741830.46875 0.726803163526442 1.7749 0.9768 3209479 TimTec1_000973 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCC=C)c3cccs3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M06 compound treatment 2881471.0 1310000.0 1.39 2854883.0 1260000.0 1.15 2201675.0 835161.46875 0.818243551745312 1.9411 0.9787 1356106 TimTec1_000974 CN(C)c1cc(O)c(C(=S)Nc2ccccc2)c(c1)N(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M07 compound treatment 2867775.0 1300000.0 1.38 2920366.0 1320000.0 1.21 2325665.0 959151.46875 0.939721878724105 2.0374 0.9885 1632278 TimTec1_000975 CC(Sc1ncnc2[nH]cnc12)c3ccccc3Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M08 compound treatment 2729841.0 1160000.0 1.23 2885351.0 1290000.0 1.18 2504114.0 1137600.46875 1.11455602640568 2.0352 0.9992 3082797 TimTec1_000976 COc1ccc(/C=N/c2ccccc2C(=O)O)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M09 compound treatment 1797142.0 225000.0 0.24 1844707.0 248000.0 0.23 1502234.0 135720.46875 0.132971170905134 0.3457 0.973 3209480 TimTec1_000977 Cc1ccccc1OCCNC(=O)c2ccco2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M10 compound treatment 2953552.0 1380000.0 1.47 2927279.0 1330000.0 1.22 2144565.0 778051.46875 0.762290432511835 1.9913 0.9692 1332157 TimTec1_000978 COc1ccc(NC(=O)c2cccc(C)c2)c(OC)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M11 compound treatment 3026810.0 1450000.0 1.55 2941874.0 1340000.0 1.23 2203499.0 836985.46875 0.820030602865639 2.0773 0.9707 3209481 TimTec1_000979 NNC(=O)CCCSc1nc2ccccc2s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M12 compound treatment 2838690.0 1270000.0 1.35 2949020.0 1350000.0 1.24 2085168.0 718654.46875 0.704096641177377 1.8987 0.9687 3082799 TimTec1_000980 Cc1ccccc1C(=O)NC#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M13 compound treatment 2916059.0 1340000.0 1.43 2919130.0 1320000.0 1.21 1952209.0 585695.46875 0.573830999780706 1.8552 0.9472 1494508 TimTec1_000981 Cc1ccc(NC(=O)n2ccnc2)cc1NC(=O)n3ccnc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M14 compound treatment 2342933.0 771000.0 0.82 1895191.0 298000.0 0.27 1508989.0 142475.46875 0.139589334456563 0.711 0.8132 1306757 TimTec1_000982 CN(C1CCCCC1)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M15 compound treatment 2376859.0 805000.0 0.85 2275395.0 678000.0 0.62 1481396.0 114882.46875 0.112555287546927 0.9174 0.8631 3082802 TimTec1_000983 COc1ccc(/C=N/c2ccc(Br)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M16 compound treatment 2550379.0 978000.0 1.04 2359704.0 763000.0 0.7 1724757.0 358243.46875 0.350986508870307 1.2061 0.9273 1154044 TimTec1_000984 COc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M17 compound treatment 2591463.0 1020000.0 1.08 2267904.0 671000.0 0.61 1889151.0 522637.46875 0.512050369547391 1.2758 0.9475 3082804 TimTec1_000985 Fc1ccc(/C=N/c2ccc3ccccc3c2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M18 compound treatment 859782.0 -713000.0 -0.76 882219.0 -715000.0 -0.66 737896.0 -628617.53125 -0.615883587432768 -1.1711 -0.9961 1441763 TimTec1_000986 CCOC(=O)c1ccc(NC(=O)c2ccco2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M19 compound treatment 1710440.0 138000.0 0.15 1739513.0 142000.0 0.13 1507286.0 140772.46875 0.137920832231828 0.2397 0.9988 1358509 TimTec1_000987 CN1CCc2nc3sc(C(=O)C(C)(C)C)c(N)c3cc2C1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M20 compound treatment 1931858.0 360000.0 0.38 1811001.0 214000.0 0.2 1411262.0 44748.46875 0.0438419962788353 0.359 0.8318 1432076 TimTec1_000988 Clc1ccc(NC(=O)CCN2CCCCC2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M21 compound treatment 1899918.0 328000.0 0.35 1624784.0 27600.0 0.03 1147688.0 -218825.53125 -0.214392769066017 0.0918 0.2241 1556893 TimTec1_000989 CCOC(=O)c1cnn(c1NC(=O)C(C)(C)C)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M22 compound treatment 1874862.0 303000.0 0.32 1466561.0 -131000.0 -0.12 1178673.0 -187840.53125 -0.184035434108054 0.0102 0.0263 3209482 TimTec1_000990 C[C@]1(O)NC(=C(C#N)C(C1[n+]2ccccc2)c3ccc(Cl)cc3)S 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M23 mock treatment 1510446.0 -61900.0 -0.07 1412758.0 -184000.0 -0.17 1120136.0 -246377.53125 -0.241386646515164 -0.2749 -0.9106 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 M24 mock treatment 1375112.0 -197000.0 -0.21 1281052.0 -316000.0 -0.29 1099636.0 -266877.53125 -0.261471376760065 -0.4392 -0.9915 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N01 compound treatment 2218550.0 646000.0 0.69 2294277.0 697000.0 0.64 1727170.0 360656.46875 0.353350628581573 0.9693 0.9671 1633893 TimTec1_000991 Oc1cccc(c1)C2=NC(=O)c3ccccc3Nc4ccccc24 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N02 compound treatment 2393346.0 821000.0 0.87 2302245.0 705000.0 0.65 1856802.0 490288.46875 0.480356665220938 1.1541 0.9721 1083978 TimTec1_000992 CCOC(=O)Nc1ccc(Cl)c(Cl)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N03 compound treatment 1854960.0 283000.0 0.3 1907184.0 310000.0 0.28 1494494.0 127980.46875 0.12538796055901 0.4098 0.9486 1379055 TimTec1_000993 CC(=O)OC1C2CCC1C(CC2)N3CCCCC3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N04 compound treatment 2861748.0 1290000.0 1.37 2876522.0 1280000.0 1.17 2086754.0 720240.46875 0.705650513478276 1.8754 0.9685 1041245 TimTec1_000994 NNC(=O)CCc1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N05 compound treatment 1921341.0 349000.0 0.37 1863682.0 266000.0 0.24 1398226.0 31712.46875 0.0310700673289559 0.3731 0.8381 1709635 TimTec1_000995 O=C(Nc1ccccc1)OC2C3CCCC2C(CC3)N4CCCCC4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N06 compound treatment 2949884.0 1380000.0 1.46 3063762.0 1470000.0 1.34 2218946.0 852432.46875 0.835164692040906 2.1033 0.9757 1189065 TimTec1_000996 Cc1ccc(C)c(NS(=O)(=O)c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N07 compound treatment 2814266.0 1240000.0 1.32 2805376.0 1210000.0 1.11 2053956.0 687442.46875 0.673516904572312 1.7901 0.9678 1163480 TimTec1_000997 CC(=O)NC1C(=O)N(Cc2ccccc2)c3ccccc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N08 compound treatment 3311757.0 1740000.0 1.85 3398095.0 1800000.0 1.65 2488744.0 1122230.46875 1.0994973774367 2.6548 0.9793 1111758 TimTec1_000998 Nc1ccc(cc1)c2nc3ccccc3[nH]2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N09 compound treatment 3110062.0 1540000.0 1.63 3058596.0 1460000.0 1.34 2156533.0 790019.46875 0.774015996003102 2.1635 0.9615 1140426 TimTec1_000999 CN(Cc1ccccc1)C(=O)c2cccc(c2)C(=O)N(C)Cc3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N10 compound treatment 1734274.0 162000.0 0.17 1696832.0 99600.0 0.09 1276140.0 -90373.53125 -0.0885428290944079 0.1009 0.4718 1327404 TimTec1_001000 COc1ccc(cc1)C(=O)NC(c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N11 compound treatment 2665235.0 1090000.0 1.16 2713891.0 1120000.0 1.02 2044421.0 677907.46875 0.664175055651086 1.6448 0.9765 3209483 TimTec1_001001 COCC(=O)Nc1cc(Sc2ccccc2)ccc1N=C(NC(=O)C)NC(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N12 compound treatment 1574634.0 2280.0 0.0 1592048.0 -5140.0 0.0 1219614.0 -146899.53125 -0.14392377845164 -0.0844 -0.5861 1566798 TimTec1_001002 CCC(CC)(CN(C)C)OC(=O)c1ccccc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N13 compound treatment 2708653.0 1140000.0 1.21 2905663.0 1310000.0 1.2 1969964.0 603450.46875 0.591226335658668 1.7308 0.9607 3209484 TimTec1_001003 CCCN1CC2(COC)CC[C@H](OC)[C@]3(CC[C@H](COC)[C@@H](O)C[C@@](C)(O)C4(O)[C@@H](OC)[C@@H]32)[C@@H]14 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N14 compound treatment 2208468.0 636000.0 0.68 2259138.0 662000.0 0.61 1925317.0 558803.46875 0.547483752671151 1.0566 0.9963 3082877 TimTec1_001004 Clc1ccc(/C=N/c2ccccn2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N15 compound treatment 2219492.0 647000.0 0.69 2403999.0 807000.0 0.74 1889552.0 523038.46875 0.51244324646584 1.1198 0.9889 3082878 TimTec1_001005 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)N3CCN(CC3)c4cccc(Cl)c4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N16 compound treatment 2000579.0 428000.0 0.46 2181516.0 584000.0 0.54 1682370.0 315856.46875 0.309458144924424 0.7506 0.9775 1649522 TimTec1_001006 O=C1NC(=O)C(CC2CCCN3CCCCC23)C(=O)N1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N17 compound treatment 2336346.0 764000.0 0.81 2634143.0 1040000.0 0.95 1632328.0 265814.46875 0.260429848782213 1.1678 0.9146 3209485 TimTec1_001007 CN(C)/C=N/c1n[nH]c(Nc2ccc(C)c(C)c2)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N18 compound treatment 2379406.0 807000.0 0.86 2526101.0 929000.0 0.85 1685320.0 318806.46875 0.312348386593812 1.167 0.935 1153859 TimTec1_001008 C[N+]12CCCCC2C(CN3C(=O)c4ccccc4C3=O)CCC1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N19 compound treatment 1616694.0 44300.0 0.05 1406893.0 -190000.0 -0.17 1224041.0 -142472.53125 -0.13958645646168 -0.1541 -0.6749 3082882 TimTec1_001009 CC(=O)NCCOc1ccc(cc1)C2CCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N20 compound treatment 3736976.0 2160000.0 2.3 4005612.0 2410000.0 2.21 3072674.0 1706160.46875 1.67159867167596 3.5675 0.9911 1577050 TimTec1_001010 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N21 compound treatment 2187701.0 615000.0 0.65 1820232.0 223000.0 0.2 1283111.0 -83402.53125 -0.0817130410682028 0.4484 0.6498 3082884 TimTec1_001011 COC(=O)c1ccccc1N(C)S(=O)(=O)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N22 compound treatment 2090746.0 518000.0 0.55 2231437.0 634000.0 0.58 1770231.0 403717.46875 0.395539339268191 0.882 0.9875 3209486 TimTec1_001012 CN(C)c1ccc(cc1)C2NCC(CSc3nc(cc(c3C#N)C(F)(F)F)c4cccs4)O2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N23 mock treatment 1582985.0 10600.0 0.01 1766171.0 169000.0 0.15 1160826.0 -205687.53125 -0.201520906336383 -0.0204 -0.0802 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 N24 mock treatment 1363821.0 -209000.0 -0.22 1305976.0 -291000.0 -0.27 1091829.0 -274684.53125 -0.269120229883086 -0.4374 -0.9963 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O01 compound treatment 2036754.0 464000.0 0.49 2217180.0 620000.0 0.57 1595480.0 228966.46875 0.224328280974208 0.7425 0.9455 1716121 TimTec1_001013 Clc1ccc(NC(=O)CC(c2ccccc2)c3ccccc3)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O02 compound treatment 2583816.0 1010000.0 1.07 2671890.0 1070000.0 0.98 1899899.0 533385.46875 0.522580646653352 1.4909 0.9627 3209487 TimTec1_001014 CCOC(=O)C(C)Sc1nc(ccc1C#N)c2cccs2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O03 compound treatment 2668843.0 1100000.0 1.17 2548440.0 951000.0 0.87 1933258.0 566744.46875 0.555263891347969 1.4966 0.9609 1595818 TimTec1_001015 O=S(=O)(NC1CCCCC1)c2cccc(c2)c3nnc(o3)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O04 compound treatment 2640192.0 1070000.0 1.13 2797552.0 1200000.0 1.1 2028294.0 661780.46875 0.648374741277451 1.6646 0.9744 1004440 TimTec1_001016 COC(=O)c1ccc(cc1)C(=O)OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O05 compound treatment 2935463.0 1360000.0 1.45 2833019.0 1240000.0 1.13 2090243.0 723729.46875 0.709068836591664 1.8996 0.9639 1455776 TimTec1_001017 OC(=O)CCC(=O)Nc1ccc(Cc2ccncc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O06 compound treatment 2825752.0 1250000.0 1.33 2835473.0 1240000.0 1.13 2215566.0 849052.46875 0.831853160907844 1.9045 0.9829 3082886 TimTec1_001018 COC1OC(C)C(OCc2ccccc2)C(O)C1O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O07 compound treatment 2846552.0 1270000.0 1.35 3044765.0 1450000.0 1.33 2340346.0 973832.46875 0.95410548480827 2.0985 0.9889 1682147 TimTec1_001019 CN(C)C(=O)CSc1nnc(N)s1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O08 compound treatment 3146097.0 1570000.0 1.67 3284242.0 1690000.0 1.55 2321017.0 954503.46875 0.935168033544675 2.3981 0.974 3082888 TimTec1_001020 OC(=O)c1ccccc1/N=C/c2ccccc2Cl 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O09 compound treatment 2870331.0 1300000.0 1.38 2935412.0 1340000.0 1.23 2131803.0 765289.46875 0.74978695312718 1.9373 0.9725 1398146 TimTec1_001021 O=C(CC1c2ccccc2Oc3ccccc13)Nc4ccccn4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O10 compound treatment 2536134.0 964000.0 1.02 2727487.0 1130000.0 1.04 2042522.0 676008.46875 0.662314523810351 1.5717 0.9822 3082890 TimTec1_001022 CCN(c1cccc(C)c1)c2ccccc2C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O11 compound treatment 2679540.0 1110000.0 1.18 2796712.0 1200000.0 1.1 2166676.0 800162.46875 0.783953528631103 1.7666 0.9864 3209488 TimTec1_001023 NC1=NN(C(=O)C1)c2ccccc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O12 compound treatment 2584906.0 1010000.0 1.08 2682365.0 1090000.0 0.99 1967849.0 601335.46875 0.589154179343157 1.5356 0.9724 1608079 TimTec1_001024 COc1ccc(cc1)C(=O)N(CC#N)CC#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O13 compound treatment 2788482.0 1220000.0 1.29 2903350.0 1310000.0 1.2 1985494.0 618980.46875 0.606441743497853 1.7874 0.9594 1340354 TimTec1_001025 CC(=O)Nc1ccc(cc1)S(=O)(=O)CCO 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O14 compound treatment 1855549.0 283000.0 0.3 1952624.0 355000.0 0.33 1436217.0 69703.46875 0.0682914813159816 0.4012 0.8942 1049845 TimTec1_001026 O=S(=O)(N1CCN(CC1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O15 compound treatment 2408831.0 836000.0 0.89 2456755.0 860000.0 0.79 1815038.0 448524.46875 0.439438681125912 1.2217 0.9647 3209489 TimTec1_001027 CC(=O)Nc1ccc(/N=C/c2cccc3ccccc23)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O16 compound treatment 1681776.0 109000.0 0.12 1855609.0 258000.0 0.24 1324374.0 -42139.53125 -0.0412859081855033 0.18 0.6742 1685172 TimTec1_001028 CCc1ccc(NS(=O)(=O)c2ccc(OC)cc2)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O17 compound treatment 1800871.0 229000.0 0.24 1639529.0 42300.0 0.04 1253121.0 -113392.53125 -0.111095531802085 0.0985 0.3649 1709515 TimTec1_001029 CC(NC(=O)c1sc2nc(C)cc(C)c2c1N)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O18 compound treatment 1994967.0 423000.0 0.45 2360653.0 763000.0 0.7 1395825.0 29311.46875 0.0287177045329556 0.6798 0.8172 3209490 TimTec1_001030 NC1=C(C#N)C(c2cccc(F)c2)n3c(=O)/c(=C\c4cccc(F)c4)/sc3=C1C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O19 compound treatment 2036658.0 464000.0 0.49 1925848.0 329000.0 0.3 1470290.0 103776.46875 0.101674262468884 0.5175 0.8816 1220431 TimTec1_001031 Cc1ccc(o1)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O20 compound treatment 1194335.0 -378000.0 -0.4 1238133.0 -359000.0 -0.33 976940.0 -389573.53125 -0.381681916376082 -0.6423 -0.9966 3209602 TimTec1_001032 CC1(C)NCCC21C(=O)N(Cc3ccccc3)c4ccccc42 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O21 compound treatment 1678319.0 106000.0 0.11 1645155.0 48000.0 0.04 1321074.0 -45439.53125 -0.0445190598834629 0.0647 0.5022 1707435 TimTec1_001033 CCN(CC)C(=O)c1c(NC(=O)c2cccs2)sc3CCCCc13 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O22 compound treatment 1810123.0 238000.0 0.25 1450027.0 -147000.0 -0.13 1240116.0 -126397.53125 -0.123837088720862 -0.0035 -0.0111 1398816 TimTec1_001034 NC1=C(C#N)C(c2ccoc2)c3c([nH]nc3O1)c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O23 mock treatment 1425238.0 -147000.0 -0.16 1476320.0 -121000.0 -0.11 1084915.0 -281598.53125 -0.275894172561781 -0.3135 -0.9333 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 O24 mock treatment 1342038.0 -230000.0 -0.24 1328687.0 -269000.0 -0.25 1030464.0 -336049.53125 -0.329242155321054 -0.4735 -0.9897 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P01 compound treatment 1994071.0 422000.0 0.45 2098142.0 501000.0 0.46 1735605.0 369091.46875 0.361614760270145 0.7326 0.9947 1265807 TimTec1_001035 O=c1cc(c2ccccc2)n(cn1)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P02 compound treatment 2177153.0 605000.0 0.64 2237443.0 640000.0 0.59 1538768.0 172254.46875 0.168765099430363 0.8073 0.9106 3209603 TimTec1_001036 CN1C2C(N=C1OCC=C)N(C)C(=O)N(C)C2=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P03 compound treatment 2138411.0 566000.0 0.6 2231749.0 635000.0 0.58 1685705.0 319191.46875 0.312725587625241 0.8636 0.9668 1404718 TimTec1_001037 COc1cc(ccc1O)C2OCC3C(C)C=C(C)C2C3C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P04 compound treatment 2275707.0 703000.0 0.75 2379775.0 783000.0 0.72 1780020.0 413506.46875 0.405130042895866 1.0795 0.9705 3082971 TimTec1_001038 CN1CN(C(=C1)c2ccccc2)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P05 compound treatment 1943192.0 371000.0 0.39 1855004.0 258000.0 0.24 1366235.0 -278.53125 -2.72889025415855E-4 0.3638 0.7917 1591413 TimTec1_001039 CC1C=C(C)C2C(C)C1(COC(=O)Nc3ccccc3)COC2c4cccnc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P06 compound treatment 2517453.0 945000.0 1.0 2540323.0 943000.0 0.86 1925349.0 558835.46875 0.547515104445192 1.395 0.973 1353881 TimTec1_001040 C=CCC1(C2CCCC2)C(=O)NC(=O)NC1=O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P07 compound treatment 905394.0 -667000.0 -0.71 911629.0 -686000.0 -0.63 721782.0 -644731.53125 -0.631671165148199 -1.1366 -0.9984 3082974 TimTec1_001041 N(=c/1\[nH]n(c[n+]1c2ccccc2)c3ccccc3)\c4ccccc4 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P08 compound treatment 3480017.0 1910000.0 2.03 3652594.0 2060000.0 1.88 2714936.0 1348422.46875 1.32110739224424 3.0207 0.9851 1117800 TimTec1_001042 Nc1ccc2oc(nc2c1)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P09 compound treatment 1840566.0 268000.0 0.29 1837450.0 240000.0 0.22 1396033.0 29519.46875 0.0289214910642209 0.3084 0.8535 3209604 TimTec1_001043 CC1C2C(O)C3C(N(C)C)C(=C(C(=O)N)C(=O)C3(O)C(=C2Cc4c(O)cccc14)O)O 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P10 compound treatment 2486624.0 914000.0 0.97 2504165.0 907000.0 0.83 2022581.0 656067.46875 0.642777469868226 1.4119 0.9866 1446940 TimTec1_001044 CCOc1ccc(cc1)C(=O)NC2CCCCC2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P11 compound treatment 2455742.0 883000.0 0.94 2338448.0 741000.0 0.68 1775526.0 409012.46875 0.400727078129008 1.1656 0.9506 3082976 TimTec1_001045 FC(F)(F)c1cccc(/N=C/c2ccccc2)c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P12 compound treatment 2094587.0 522000.0 0.55 2230620.0 633000.0 0.58 1483642.0 117128.46875 0.114755790187417 0.7218 0.8898 3209605 TimTec1_001046 CC[N+](C)(CC)C/C=C\1/COCO1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P13 compound treatment 2424219.0 852000.0 0.91 2443788.0 847000.0 0.78 1841591.0 475077.46875 0.465453795379221 1.2393 0.9683 1357190 TimTec1_001047 COc1ccc(CC(=O)N(CC#N)CC#N)cc1OC 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P14 compound treatment 2209090.0 637000.0 0.68 1906000.0 309000.0 0.28 1516163.0 149649.46875 0.14661801029934 0.6387 0.8539 3082979 TimTec1_001048 C1OCc2cccc(/C=N/c3nccs3)c2O1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P15 compound treatment 2305217.0 733000.0 0.78 2050491.0 453000.0 0.42 1774940.0 408426.46875 0.400152948766886 0.9205 0.9498 3209606 TimTec1_001049 Cc1cc(C)nc(SCc2nc3ccccc3c(=O)n2c4ccc(cc4)C(F)(F)F)n1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P16 compound treatment 2349659.0 777000.0 0.83 2383529.0 786000.0 0.72 1985081.0 618567.46875 0.606037109664139 1.2429 0.9923 2110705 TimTec1_001050 CN(C)c1ccc(/C=N/CC2CCCN3CCCCC23)cc1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P17 compound treatment 2259211.0 687000.0 0.73 2322532.0 725000.0 0.66 1586738.0 220224.46875 0.215763368203431 0.9298 0.9201 3082982 TimTec1_001051 OC(=O)C(CC(=O)c1ccc(Br)cc1)NCCc2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P18 compound treatment 2157175.0 585000.0 0.62 1881293.0 284000.0 0.26 1809884.0 443370.46875 0.434389086019462 0.7599 0.9479 3209607 TimTec1_001052 OC(=O)c1cc(/C=N/c2ccc(cc2)S(=O)(=O)NC3NC=CS3)c4OCOCc4c1 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P19 compound treatment 1941998.0 370000.0 0.39 1900812.0 304000.0 0.28 1729981.0 363467.46875 0.356104685982471 0.593 0.9904 1482831 TimTec1_001053 CN(c1cccc2cccnc12)S(=O)(=O)c3ccccc3 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P20 compound treatment 1699305.0 127000.0 0.13 1730083.0 133000.0 0.12 1495274.0 128760.46875 0.126152160051255 0.221 0.9991 1207395 TimTec1_001054 CC(C)COC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(Cl)cc2 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P21 compound treatment 968019.0 -604000.0 -0.64 925174.0 -672000.0 -0.62 754885.0 -611628.53125 -0.599238734645908 -1.0723 -0.9996 3082984 TimTec1_001055 Cn1c(S)nc2sc3CC(CCc3c2c1=O)C(C)(C)C 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P22 compound treatment 1413550.0 -159000.0 -0.17 1403510.0 -194000.0 -0.18 1411012.0 44498.46875 0.0435970605441414 -0.1747 -0.7024 3209608 TimTec1_001056 CCN(CC)C(=S)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P23 mock treatment 1476656.0 -95700.0 -0.1 1552661.0 -44500.0 -0.04 1432104.0 65590.46875 0.0642617986087973 -0.0452 -0.3556 1010.0066 DAPIStaining(1010.0066) PlasmodiumViabilityAssay 1010.0066.2065 P24 mock treatment 1432183.0 -140000.0 -0.15 1425359.0 -172000.0 -0.16 1225011.0 -141502.53125 -0.138636105811068 -0.257 -0.9987